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Sample records for the next step device

  1. An approach to next step device optimisation

    International Nuclear Information System (INIS)

    Salpietro, E.

    2000-01-01

    The requirements for ITER EDA were to achieve ignition with a good safety margin, and controlled long inductive burn. These requirements lead to a big device, which requested a too ambitious step to be undertaken by the world fusion community. More realistic objectives for a next step device shall be to demonstrate the net production of energy with a high energy gain factor (Q) and a high boot strap current fraction (>60%) which is required for a Fusion Power Plant (FPP). The Next Step Device (NSD) shall also allow operation flexibility in order to explore a large range of plasma parameters to find out the optimum concept for the fusion power plant prototype. These requirements could be too demanding for one single device and could probably be better explored in a strongly integrated world programme. The cost of one or more devices is the decisive factor for the choice of the fusion power development programme strategy. The plasma elongation and triangularity have a strong impact in the cost of the device and are limited by the plasma vertical position control issue. The distance between plasma separatrix and the toroidal field conductor does not vary a lot between devices. It is determined by the sum of the distance between first wall-plasma sepratrix and the thickness of the nuclear shield required to protect the toroidal field coil insultation. The thickness of the TF coil is determined by the allowable stresses and superconducting characteristics. The outer radius of the central solenoid is the result of an optimisation to provide the magnetic flux to inductively drive the plasma. Therefore, in order to achieve the objectives for Q and boot-strap current fractions at the minimum cost, the plasma aspect ratio and magnetic field value shall be determined. The paper will present the critical issues for the next device and will make considerations on the optimal way to proceed towards the realisation of the fusion power plant

  2. Tritium Issues in Next Step Devices

    Energy Technology Data Exchange (ETDEWEB)

    C.H. Skinner; G. Federici

    2001-09-05

    Tritium issues will play a central role in the performance and operation of next-step deuterium-tritium (DT) burning plasma tokamaks and the safety aspects associated with tritium will attract intense public scrutiny. The orders-of-magnitude increase in duty cycle and stored energy will be a much larger change than the increase in plasma performance necessary to achieve high fusion gain and ignition. Erosion of plasma-facing components will scale up with the pulse length from being barely measurable on existing machines to centimeter scale. Magnetic Fusion Energy (MFE) devices with carbon plasma-facing components will accumulate tritium by co-deposition with the eroded carbon and this will strongly constrain plasma operations. We report on a novel laser-based method to remove co-deposited tritium from carbon plasma-facing components in tokamaks. A major fraction of the tritium trapped in a co-deposited layer during the deuterium-tritium (DT) campaign on the Tokamak Fusion Test Reactor (TFTR) was released by heating with a scanning laser beam. This technique offers the potential for tritium removal in a next-step DT device without the use of oxidation and the associated deconditioning of the plasma-facing surfaces and expense of processing large quantities of tritium oxide. The operational lifetime of alternative materials such as tungsten has significant uncertainties due to melt layer loss during disruptions. Production of dust and flakes will need careful monitoring and minimization, and control and accountancy of the tritium inventory will be critical issues. Many of the tritium issues in Inertial Fusion Energy (IFE) are similar to MFE, but some, for example those associated with the target factory, are unique to IFE. The plasma-edge region in a tokamak has greater complexity than the core due to lack of poloidal symmetry and nonlinear feedback between the plasma and wall. Sparse diagnostic coverage and low dedicated experimental run time has hampered the

  3. Tritium Issues in Next Step Devices

    International Nuclear Information System (INIS)

    C.H. Skinner; G. Federici

    2001-01-01

    Tritium issues will play a central role in the performance and operation of next-step deuterium-tritium (DT) burning plasma tokamaks and the safety aspects associated with tritium will attract intense public scrutiny. The orders-of-magnitude increase in duty cycle and stored energy will be a much larger change than the increase in plasma performance necessary to achieve high fusion gain and ignition. Erosion of plasma-facing components will scale up with the pulse length from being barely measurable on existing machines to centimeter scale. Magnetic Fusion Energy (MFE) devices with carbon plasma-facing components will accumulate tritium by co-deposition with the eroded carbon and this will strongly constrain plasma operations. We report on a novel laser-based method to remove co-deposited tritium from carbon plasma-facing components in tokamaks. A major fraction of the tritium trapped in a co-deposited layer during the deuterium-tritium (DT) campaign on the Tokamak Fusion Test Reactor (TFTR) was released by heating with a scanning laser beam. This technique offers the potential for tritium removal in a next-step DT device without the use of oxidation and the associated deconditioning of the plasma-facing surfaces and expense of processing large quantities of tritium oxide. The operational lifetime of alternative materials such as tungsten has significant uncertainties due to melt layer loss during disruptions. Production of dust and flakes will need careful monitoring and minimization, and control and accountancy of the tritium inventory will be critical issues. Many of the tritium issues in Inertial Fusion Energy (IFE) are similar to MFE, but some, for example those associated with the target factory, are unique to IFE. The plasma-edge region in a tokamak has greater complexity than the core due to lack of poloidal symmetry and nonlinear feedback between the plasma and wall. Sparse diagnostic coverage and low dedicated experimental run time has hampered the

  4. Tritium inventory and recovery in next-step fusion devices

    International Nuclear Information System (INIS)

    Causey, R.A.; Brooks, J.N.; Federici, G.

    2002-01-01

    Future fusion devices will use tritium and deuterium fuel. Because tritium is both radioactive and expensive, it is absolutely necessary that there be an understanding of the tritium retention characteristics of the materials used in these devices as well as how to recover the tritium. There are three materials that are strong candidates for plasma-facing-material use in next-step fusion devices. These are beryllium, tungsten, and carbon. While beryllium has the disadvantage of high sputtering and low melting point (which limits its power handling capabilities in divertor areas), it has the advantages of being a low-Z material with a good thermal conductivity and the ability to get oxygen from the plasma. Due to beryllium's very low solubility for hydrogen, implantation of beryllium with deuterium and tritium results in a saturated layer in the very near-surface with limited inventory (J. Nucl. Mater. 273 (1999) 1). Unfortunately, there are nuclear reactions generated by neutrons that will breed tritium and helium in the material bulk (J. Nucl. Mater. 179 (1991) 329). This process will lead to a substantial tritium inventory in the bulk of the beryllium after long-term neutron exposure (i.e. well beyond the operation life time of a next-step reactor like ITER). Tungsten is a high-Z material that will be used in the divertor region of next-step devices (e.g. ITER) and possibly as a first wall material in later devices. The divertor is the preferred location for tungsten use because net erosion is very low there due to low sputtering and high redeposition. While experiments are still continuing on tritium retention in tungsten, present data suggest that relatively low tritium inventories will result with this material (J. Nucl. Mater. 290-293 (2001) 505). For tritium inventories, carbon is the problem material. Neutron damage to the graphite can result in substantial bulk tritium retention (J. Nucl. Mater. 191-194 (1992) 368), and codeposition of the sputtered carbon

  5. Developing Boundary/PMI Solutions for Next-Step Fusion Devices

    Science.gov (United States)

    Guo, H. Y.; Leonard, A. W.; Thomas, D. M.; Allen, S. L.; Hill, D. N.; Unterberg, Z.

    2014-10-01

    The path towards next-step fusion development requires increased emphasis on the boundary/plasma-material interface. The new DIII-D Boundary/Plasma-Material Interactions (PMI) Center has been established to address these critical issues on a timescale relevant to the design of FNSF, adopting the following transformational approaches: (1) Develop and test advanced divertor configurations on DIII-D compatible with core plasma high performance operational scenarios in FNSF; (2) Validate candidate reactor PFC materials at reactor-relevant temperatures in DIII-D high-performance plasmas, in collaboration with the broad material research/development community; (3) Integrate validated boundary-materials interface with high performance plasmas to provide viable boundary/PMI solutions for next-step fusion devices. This program leverages unique DIII-D capabilities, promotes synergistic programs within the broad PMI community, including linear material research facilities. It will also enable us to build a compelling bridge for the US research on long-pulse facilities. Work supported by the US DOE under DE-FC02-04ER54698 and DE-AC52-07NA27344, DE-AC05-00OR2725.

  6. Proceedings of the international workshop on engineering design of next step reversed field pinch devices

    International Nuclear Information System (INIS)

    Thomson, D.B.

    1987-11-01

    These Proceedings contain the formal contributed papers, the workshop papers and workshop summaries presented at the International Workshop on Engineering Design of Next Step RFP Devices held at Los Alamos, July 13-17, 1987. Contributed papers were presented at formal sessions on the topics: (1) physics overview (3 papers); (2) general overview (3 papers); (3) front-end (9 papers); (4) computer control and data acquisition (1 paper); (5) magnetics (5 papers); and (6) electrical design (9 papers). Informal topical workshop sessions were held on the topics: (1) RFP physics (9 papers); (2) front-end (7 papers); (3) magnetics (3 papers); and (4) electrical design (1 paper). This volume contains the summaries written by the Chairmen of each of the informal topical workshop sessions. The papers in these Proceedings represent a significant review of the status of the technical base for the engineering design of the next step RFP devices being developed in the US, Europe, and Japan, as of this date

  7. Proceedings of the international workshop on engineering design of next step reversed field pinch devices

    Energy Technology Data Exchange (ETDEWEB)

    Thomson, D.B. (comp.)

    1987-11-01

    These Proceedings contain the formal contributed papers, the workshop papers and workshop summaries presented at the International Workshop on Engineering Design of Next Step RFP Devices held at Los Alamos, July 13-17, 1987. Contributed papers were presented at formal sessions on the topics: (1) physics overview (3 papers); (2) general overview (3 papers); (3) front-end (9 papers); (4) computer control and data acquisition (1 paper); (5) magnetics (5 papers); and (6) electrical design (9 papers). Informal topical workshop sessions were held on the topics: (1) RFP physics (9 papers); (2) front-end (7 papers); (3) magnetics (3 papers); and (4) electrical design (1 paper). This volume contains the summaries written by the Chairmen of each of the informal topical workshop sessions. The papers in these Proceedings represent a significant review of the status of the technical base for the engineering design of the next step RFP devices being developed in the US, Europe, and Japan, as of this date.

  8. Deposition Diagnostics for Next-step Devices

    International Nuclear Information System (INIS)

    Skinner, C.H.; Roquemore, A.L.; Bader, A.; Wampler, W.R.

    2004-01-01

    The scale-up of deposition in next-step devices such as ITER will pose new diagnostic challenges. Codeposition of hydrogen with carbon needs to be characterized and understood in the initial hydrogen phase in order to mitigate tritium retention and qualify carbon plasma facing components for DT operations. Plasma facing diagnostic mirrors will experience deposition that is expected to rapidly degrade their reflectivity, posing a new challenge to diagnostic design. Some eroded particles will collect as dust on interior surfaces and the quantity of dust will be strictly regulated for safety reasons - however diagnostics of in-vessel dust are lacking. We report results from two diagnostics that relate to these issues. Measurements of deposition on NSTX with 4 Hz time resolution have been made using a quartz microbalance in a configuration that mimics that of a typical diagnostic mirror. Often deposition was observed immediately following the discharge suggesting that diagnostic shutters should be closed as soon as possible after the time period of interest. Material loss was observed following a few discharges. A novel diagnostic to detect surface particles on remote surfaces was commissioned on NSTX

  9. Neutral pumping rates for a next step tokamak ignition device

    International Nuclear Information System (INIS)

    Galambos, J.D.; Peng, Y.K.M.; Heifetz, D.

    1985-01-01

    Neutral pumping rates are calculated for pump-limiter and divertor options of a next step tokamak ignition device using a method that accounts for the coupled effects of neutral transport and plasma transport. For both pump limiters and divertors the plasma flow into the channel surrounding the neutralizer plate is greatly reduced by the neutral recycling. The fraction of this flow that is pumped can be large (>50%) but in general is dependent on the particular geometry and plasma conditions. It is estimated that pumping speeds greater than or approximately 10 5 L/s are adequate for the exhaust requirements in the pump-limiter and the divertor cases

  10. Alternative divertor target concepts for next step fusion devices

    Science.gov (United States)

    Mazul, I. V.

    2016-12-01

    The operational conditions of a divertor target in the next steps of fusion devices are more severe in comparison with ITER. The current divertor designs and technologies have a limited application concerning these conditions, and so new design concepts/technologies are required. The main reasons which practically prevent the use of the traditional motionless solid divertor target are analyzed. We describe several alternative divertor target concepts in this paper. The comparative analysis of these concepts (including the advantages and the drawbacks) is made and the prospects for their practical implementation are prioritized. The concept of the swept divertor target with a liquid metal interlayer between the moving armour and motionless heat-sink is presented in more detail. The critical issues of this design are listed and outlined, and the possible experiments are presented.

  11. Tandem mirror next step conceptual design

    International Nuclear Information System (INIS)

    Doggett, J.N.; Damm, C.C.; Bulmer, R.H.

    1980-01-01

    A study was made to define the features of the experimental mirror fusion device - The Tandem Mirror Next Step, or TMNS - that will bridge the gap between present mirror confinement experiments and a power-producing reactor. We outline the project goals, describe some initial device parameters, and relate the technological requirements to ongoing development programs

  12. Status of the mirror-next-step (MNS) study

    International Nuclear Information System (INIS)

    Damm, C.C.; Doggett, J.N.; Bulmer, R.H.

    1979-09-01

    A study was made to define the features of the experimental mirror fusion device - the Mirror Next Step, or MNS - that will bridge the gap between present mirror confinement experiments and a power-producing reactor. The project goals and organization of the study are outlined, some initial device parameters are described, and the technological requirements are related to ongoing development programs

  13. Tandem mirror next step: remote maintenance

    International Nuclear Information System (INIS)

    Doggett, J.N.; Damm, C.C.; Hanson, C.L.

    1980-01-01

    This study of the next proposed experiment in the Mirror Fusion Program, the Tandem Mirror Next Step (TMNS), has included serious consideration of the maintenance requirements of such a large source of high energy neutrons with its attendant throughput of tritium. Although maintenance will be costly in time and money, our conclusion is that with careful attention to a design for maintenance plan such a device can be reliably operated

  14. Next Step Spherical Torus Design Studies

    International Nuclear Information System (INIS)

    Neumeyer, C.; Heitzenroeder, P.; Kessel, C.; Ono, M.; Peng, M.; Schmidt, J.; Woolley, R.; Zatz, I.

    2002-01-01

    Studies are underway to identify and characterize a design point for a Next Step Spherical Torus (NSST) experiment. This would be a ''Proof of Performance'' device which would follow and build upon the successes of the National Spherical Torus Experiment (NSTX) a ''Proof of Principle'' device which has operated at PPPL since 1999. With the Decontamination and Decommissioning (DandD) of the Tokamak Fusion Test Reactor (TFTR) nearly completed, the TFTR test cell and facility will soon be available for a device such as NSST. By utilizing the TFTR test cell, NSST can be constructed for a relatively low cost on a short time scale. In addition, while furthering spherical torus (ST) research, this device could achieve modest fusion power gain for short-pulse lengths, a significant step toward future large burning plasma devices now under discussion in the fusion community. The selected design point is Q=2 at HH=1.4, P subscript ''fusion''=60 MW, 5 second pulse, with R subscript ''0''=1.5 m, A=1.6, I subscript ''p''=10vMA, B subscript ''t''=2.6 T, CS flux=16 weber. Most of the research would be conducted in D-D, with a limited D-T campaign during the last years of the program

  15. Challenges for Plasma Diagnostic in a Next Step Device (FIRE)

    International Nuclear Information System (INIS)

    Young, Kenneth M.

    2002-01-01

    The physics program of any next-step tokamak such as FIRE [Fusion Ignition Research Experiment] sets demands for plasma measurement which are at least as comprehensive as on present tokamaks, with the additional capabilities needed for control of the plasma and for understanding the effects of the alpha-particles. The diagnostic instrumentation must be able to provide the fine spatial and temporal resolution required for the advanced tokamak plasma scenarios. It must also be able to overcome the effects of neutron- and gamma-induced electrical noise in ceramic components or detectors, and fluorescence and absorption in optical components. There are practical engineering issues of minimizing radiation streaming while providing essential diagnostic access to the plasma. Many diagnostics will require components at or close to the first wall, e.g., ceramics and MI cable for magnetic diagnostics and mirrors for optical diagnostics; these components must be mounted to operate, and survive, i n fluxes which require special material selection. A better set of diagnostics of alpha-particles than that available for the TFTR [Tokamak Fusion Test Reactor] is essential; it must be qualified well before moving into D-T [deuterim-tritium] experiments. A start has been made to assessing the potential implementation of key diagnostics for the FIRE device. The present status is described

  16. Implications of fusion results for a reactor: a proposed next step device-JIT

    International Nuclear Information System (INIS)

    Rebut, P.H.

    1989-01-01

    Simulations with a critical-temperature model have been made of proposed future devices (NET, ITER, JIT, etc.). These show that only machines with a current capability of ∼ 30MA have a sufficient ignition domain to cope with more realistic operating conditions (i.e. taking into account sawteeth effects, impurity dilution and semi-continuous operation). The importance of dilution and Bremsstrahlung radiation are clearly demonstrated; a mean temperature > 7keV is required for ignition. This prevents higher field, lower current devices from reaching ignition. Transient operations with monster sawteeth or H-mode allow such devices (>30MA) to reach ignition at lower density without additional heating. To investigate the problems of a controlled burning plasma for days in semi-continuous operation, the plasma of the next-step tokamak should be similar in size and performance to an energy producing reactor. The scientific and technical aims of such a machine should be to study burning plasma, test wall technology, provide a test-bed for breeding blankets and most importantly to demonstrate the potential and viability of fusion as an energy source. The main design characteristics of a Thermonuclear Furnace-JIT-dedicated to these objectives are presented. Watercooled copper magnets are used to benefit from proven technology. A single-null divertor configuration ensures helium exhaust and possibly benefits from an H-mode to reach the ignition domain. The X-point position relative to the dump plates would be swept to limit wall loading

  17. A Microfluidic Device for Preparing Next Generation DNA Sequencing Libraries and for Automating Other Laboratory Protocols That Require One or More Column Chromatography Steps

    Science.gov (United States)

    Tan, Swee Jin; Phan, Huan; Gerry, Benjamin Michael; Kuhn, Alexandre; Hong, Lewis Zuocheng; Min Ong, Yao; Poon, Polly Suk Yean; Unger, Marc Alexander; Jones, Robert C.; Quake, Stephen R.; Burkholder, William F.

    2013-01-01

    Library preparation for next-generation DNA sequencing (NGS) remains a key bottleneck in the sequencing process which can be relieved through improved automation and miniaturization. We describe a microfluidic device for automating laboratory protocols that require one or more column chromatography steps and demonstrate its utility for preparing Next Generation sequencing libraries for the Illumina and Ion Torrent platforms. Sixteen different libraries can be generated simultaneously with significantly reduced reagent cost and hands-on time compared to manual library preparation. Using an appropriate column matrix and buffers, size selection can be performed on-chip following end-repair, dA tailing, and linker ligation, so that the libraries eluted from the chip are ready for sequencing. The core architecture of the device ensures uniform, reproducible column packing without user supervision and accommodates multiple routine protocol steps in any sequence, such as reagent mixing and incubation; column packing, loading, washing, elution, and regeneration; capture of eluted material for use as a substrate in a later step of the protocol; and removal of one column matrix so that two or more column matrices with different functional properties can be used in the same protocol. The microfluidic device is mounted on a plastic carrier so that reagents and products can be aliquoted and recovered using standard pipettors and liquid handling robots. The carrier-mounted device is operated using a benchtop controller that seals and operates the device with programmable temperature control, eliminating any requirement for the user to manually attach tubing or connectors. In addition to NGS library preparation, the device and controller are suitable for automating other time-consuming and error-prone laboratory protocols requiring column chromatography steps, such as chromatin immunoprecipitation. PMID:23894273

  18. A microfluidic device for preparing next generation DNA sequencing libraries and for automating other laboratory protocols that require one or more column chromatography steps.

    Directory of Open Access Journals (Sweden)

    Swee Jin Tan

    Full Text Available Library preparation for next-generation DNA sequencing (NGS remains a key bottleneck in the sequencing process which can be relieved through improved automation and miniaturization. We describe a microfluidic device for automating laboratory protocols that require one or more column chromatography steps and demonstrate its utility for preparing Next Generation sequencing libraries for the Illumina and Ion Torrent platforms. Sixteen different libraries can be generated simultaneously with significantly reduced reagent cost and hands-on time compared to manual library preparation. Using an appropriate column matrix and buffers, size selection can be performed on-chip following end-repair, dA tailing, and linker ligation, so that the libraries eluted from the chip are ready for sequencing. The core architecture of the device ensures uniform, reproducible column packing without user supervision and accommodates multiple routine protocol steps in any sequence, such as reagent mixing and incubation; column packing, loading, washing, elution, and regeneration; capture of eluted material for use as a substrate in a later step of the protocol; and removal of one column matrix so that two or more column matrices with different functional properties can be used in the same protocol. The microfluidic device is mounted on a plastic carrier so that reagents and products can be aliquoted and recovered using standard pipettors and liquid handling robots. The carrier-mounted device is operated using a benchtop controller that seals and operates the device with programmable temperature control, eliminating any requirement for the user to manually attach tubing or connectors. In addition to NGS library preparation, the device and controller are suitable for automating other time-consuming and error-prone laboratory protocols requiring column chromatography steps, such as chromatin immunoprecipitation.

  19. NextSTEP Hybrid Life Support

    Data.gov (United States)

    National Aeronautics and Space Administration — NextSTEP Phase I Hybrid Life Support Systems (HLSS) effort assessed options, performance, and reliability for various mission scenarios using contractor-developed...

  20. Advanced Electric Propulsion NextSTEP BAA Activity

    Data.gov (United States)

    National Aeronautics and Space Administration — The goal of the AES Advanced Electric Propulsion Next Space Technologies for Exploration Partnerships (NextSTEP) Broad Agency Announcement (BAA) activity is to...

  1. Integrated concept development of next-step helical-axis advanced stellarators

    Energy Technology Data Exchange (ETDEWEB)

    Warmer, Felix

    2016-04-13

    With the increasing energy demand of mankind and the transformation of our society towards sustainability, nuclear fusion by magnetic confinement is a promising option for the sustainable electricity supply in the future. In view of these prospects this thesis focuses on the concept development of next-step helical-axis advanced stellarator (HELIAS) burning-plasma devices. The HELIAS-line is the continued development of the prototype optimised stellarator Wendelstein 7-X which started operation in 2015. For the integrated concept development of such devices, the approach taken in this work encompasses detailed physics and engineering considerations while also including economic aspects. Starting with physics considerations, the properties of plasma transport and confinement of 3D stellarator configurations are discussed due to their critical importance for the device design. It becomes clear that current empirical confinement time scalings are not sufficient to predict the confinement in future stellarator devices. Therefore, detailed 1D transport simulations are carried out to reduce the uncertainties regarding confinement. Beyond the well-validated neoclassical approach, first attempts are made to include results from state-of-the-art turbulence simulations into the 1D transport simulations to further enhance the predictive capabilities. Next, for the systematic development of consistent design points, stellarator-specific models are developed and implemented in the well-established European systems code PROCESS. This allows a consistent description of an entire HELIAS fusion power plant including physics, engineering, and economic considerations. With the confidence obtained from a verification study, systems studies are for the first time applied for a HELIAS power-plant which shows that the available design window is constrained by the beta-limit. Furthermore, an economic comparison of an exemplary design point to an ''equivalent'' tokamak

  2. Next generation toroidal devices

    International Nuclear Information System (INIS)

    Yoshikawa, Shoichi

    1998-10-01

    A general survey of the possible approach for the next generation toroidal devices was made. Either surprisingly or obviously (depending on one's view), the technical constraints along with the scientific considerations lead to a fairly limited set of systems for the most favorable approach for the next generation devices. Specifically if the magnetic field strength of 5 T or above is to be created by superconducting coils, it imposes minimum in the aspect ratio for the tokamak which is slightly higher than contemplated now for ITER design. The similar technical constraints make the minimum linear size of a stellarator large. Scientifically, it is indicated that a tokamak of 1.5 times in the linear dimension should be able to produce economically, especially if a hybrid reactor is allowed. For the next stellarator, it is strongly suggested that some kind of helical axis is necessary both for the (almost) absolute confinement of high energy particles and high stability and equilibrium beta limits. The author still favors a heliac most. Although it may not have been clearly stated in the main text, the stability afforded by the shearless layer may be exploited fully in a stellarator. (author)

  3. Next generation toroidal devices

    Energy Technology Data Exchange (ETDEWEB)

    Yoshikawa, Shoichi [Princeton Plasma Physics Lab., Princeton Univ., NJ (United States)

    1998-10-01

    A general survey of the possible approach for the next generation toroidal devices was made. Either surprisingly or obviously (depending on one`s view), the technical constraints along with the scientific considerations lead to a fairly limited set of systems for the most favorable approach for the next generation devices. Specifically if the magnetic field strength of 5 T or above is to be created by superconducting coils, it imposes minimum in the aspect ratio for the tokamak which is slightly higher than contemplated now for ITER design. The similar technical constraints make the minimum linear size of a stellarator large. Scientifically, it is indicated that a tokamak of 1.5 times in the linear dimension should be able to produce economically, especially if a hybrid reactor is allowed. For the next stellarator, it is strongly suggested that some kind of helical axis is necessary both for the (almost) absolute confinement of high energy particles and high stability and equilibrium beta limits. The author still favors a heliac most. Although it may not have been clearly stated in the main text, the stability afforded by the shearless layer may be exploited fully in a stellarator. (author)

  4. The CTB Treaty and next steps towards nuclear disarmament

    International Nuclear Information System (INIS)

    Epstein, W.

    1998-01-01

    The achievement of a CTBT is of course the indispensable first step in any program of nuclear disarmament. It will not be easy for Conference on Disarmament to agree by consensus to establish the committee on nuclear disarmament and will be even more difficult for it to agree on its mandate or terms of reference. In the meantime the nuclear powers should seek to implement a number of steps towards nuclear disarmament which thy can argue and implement by their own accord. The next steps are described in this report

  5. Next Steps in Signaling (NSIS): Framework

    NARCIS (Netherlands)

    Hancock, R.; Loughney, J.; van den Bosch, S.; Hancock, R.; Karagiannis, Georgios; Loughney, J.; van den Bosch, S.

    The Next Steps in Signaling (NSIS) working group is considering protocols for signaling information about a data flow along its path in the network. The NSIS suite of protocols is envisioned to support various signaling applications that need to install and/or manipulate such state in the network.

  6. An Initial Evaluation of Tablet Devices & What Are the Next Steps?

    Science.gov (United States)

    McKillen, Tracey

    2016-01-01

    This paper describes an evaluation of tablet devices for a Graduate Entry Medical School (GEMS). The purpose of this evaluation is to assess what type of tablet device could meet the needs of a GEMS student. GEMS requirements for the evaluation include; using the tablet device to replace paper teaching resources in lectures and tutorials and…

  7. Multi-User Interactive TV: the Next Step in Personalization

    NARCIS (Netherlands)

    van Brandenburg, Ray; van Deventer, M. Oskar; Karagiannis, Georgios; Schenk, Mike

    2010-01-01

    In the past few years there has been an increasing trend towards personalization in the TV world. IMS-based IPTV is a good example of a highly personalized IPTV architecture, featuring an advanced identity management subsystem. This article studies a next step in the personalization of the

  8. Next-Step scientific objectives, targets, and parameters for reversed-field-pinch (RFP) magnetic fusion energy (MFE) systems: Preliminary thoughts

    International Nuclear Information System (INIS)

    Krakowski, R.A.; Bathke, C.G.; DiMarco, J.N.; Miller, R.L.; Werley, K.A.

    1993-01-01

    The purpose of this document is the quantitative definition of objectives, targets, and parameters of the Next-Step device to follow the present RFX experiment; this device is given the name RFXNS. Although developed over five years ago, much of the material distilled into the 1988 RFP tactical plan is useful in establishing the goals and parameters of RFXNS. This earlier plan established tentative parameters of an RFP next step based on: predictions of RFP ignition and commercial-reactor devices; and the assumed successful operation of highly complementary RFP experiments RFX and ZTH/CPRF. Programmatic changes and evolution that have occurred since 1988 strongly impact the role and characteristics of an RFXNS: the Los Alamos ZTH/CPRF project and fusion program was terminated in mid-construction for reasons of MFE cost savings and concept focusing; great progress has been made in launching ITER; and reactor projections for the tokamak have increased in detail and variety, but not in commercial promise and competitiveness. A brief status of and perspective from each of the above three points is necessary before the key issues and their implementation to form the basis of the RFXNS definition are given

  9. Working together in future: next steps

    International Nuclear Information System (INIS)

    Copeland, S.

    2001-01-01

    Some questions about public trust have to find answers: the language of safety, how much is enough, how much is too much for stake holder interaction, how do you deal with the issue of responding, i.e. demonstrating action on issues when the licensing decision is not what public groups want, how do you measure the success of consultations, what are the indicators for trust, benchmarking and measuring public perceptions, need for consistency of approach (can determine public confidence by differences between countries) are so many questions that could help for next steps. (N.C.)

  10. Mobile Device Accuracy for Step Counting Across Age Groups.

    Science.gov (United States)

    Modave, François; Guo, Yi; Bian, Jiang; Gurka, Matthew J; Parish, Alice; Smith, Megan D; Lee, Alexandra M; Buford, Thomas W

    2017-06-28

    Only one in five American meets the physical activity recommendations of the Department of Health and Human Services. The proliferation of wearable devices and smartphones for physical activity tracking has led to an increasing number of interventions designed to facilitate regular physical activity, in particular to address the obesity epidemic, but also for cardiovascular disease patients, cancer survivors, and older adults. However, the inconsistent findings pertaining to the accuracy of wearable devices for step counting needs to be addressed, as well as factors known to affect gait (and thus potentially impact accuracy) such as age, body mass index (BMI), or leading arm. We aim to assess the accuracy of recent mobile devices for counting steps, across three different age groups. We recruited 60 participants in three age groups: 18-39 years, 40-64 years, and 65-84 years, who completed two separate 1000 step walks on a treadmill at a self-selected speed between 2 and 3 miles per hour. We tested two smartphones attached on each side of the waist, and five wrist-based devices worn on both wrists (2 devices on one wrist and 3 devices on the other), as well as the Actigraph wGT3X-BT, and swapped sides between each walk. All devices were swapped dominant-to-nondominant side and vice-versa between the two 1000 step walks. The number of steps was recorded with a tally counter. Age, sex, height, weight, and dominant hand were self-reported by each participant. Among the 60 participants, 36 were female (60%) and 54 were right-handed (90%). Median age was 53 years (min=19, max=83), median BMI was 24.1 (min=18.4, max=39.6). There was no significant difference in left- and right-hand step counts by device. Our analyses show that the Fitbit Surge significantly undercounted steps across all age groups. Samsung Gear S2 significantly undercounted steps only for participants among the 40-64 year age group. Finally, the Nexus 6P significantly undercounted steps for the group

  11. Space Drive Physics: Introduction and Next Steps

    Science.gov (United States)

    Millis, M. G.

    Research toward the visionary goal of propellantless ``space drives'' is introduced, covering key physics issues and a listing of roughly 2-dozen approaches. The targeted advantage of a space drive is to circumvent the propellant constraints of rockets and the maneuvering limits of light sails by using the interactions between the spacecraft and its surrounding space for propulsion. At present, the scientific foundations from which to engineer a space drive have not been discovered and, objectively, might be impossible. Although no propulsion breakthroughs appear imminent, the subject has matured to where the relevant questions have been broached and are beginning to be answered. The critical make-break issues include; conservation of momentum, uncertain sources of reaction mass, and the net-external thrusting requirement. Note: space drives are not necessarily faster- than-light devices. Speed limits are a separate, unanswered issue. Relevant unsolved physics includes; the sources and mechanisms of inertial frames, coupling of gravitation and electromagnetism, and the nature of the quantum vacuum. The propulsion approaches span mostly stages 1 through 3 of the scientific method (defining the problem, collecting data, and articulating hypotheses), while some have matured to stage 4 (testing hypotheses). Nonviable approaches include `stiction drives,' `gyroscopic antigravity,' and `lifters.' No attempt is made to gauge the prospects of the remaining approaches. Instead, a list of next-step research questions is derived from the examination of these goals, unknowns, and concepts.

  12. The next step in biology: a periodic table?

    Science.gov (United States)

    Dhar, Pawan K

    2007-08-01

    Systems biology is an approach to explain the behaviour of a system in relation to its individual components. Synthetic biology uses key hierarchical and modular concepts of systems biology to engineer novel biological systems. In my opinion the next step in biology is to use molecule-to-phenotype data using these approaches and integrate them in the form a periodic table. A periodic table in biology would provide chassis to classify, systematize and compare diversity of component properties vis-a-vis system behaviour. Using periodic table it could be possible to compute higher- level interactions from component properties. This paper examines the concept of building a bio-periodic table using protein fold as the fundamental unit.

  13. Next-Step Spherical Torus Experiment and Spherical Torus Strategy in the Fusion Energy Development Path

    International Nuclear Information System (INIS)

    Ono, M.; Peng, M.; Kessel, C.; Neumeyer, C.; Schmidt, J.; Chrzanowski, J.; Darrow, D.; Grisham, L.; Heitzenroeder, P.; Jarboe, T.; Jun, C.; Kaye, S.; Menard, J.; Raman, R.; Stevenson, T.; Viola, M.; Wilson, J.; Woolley, R.; Zatz, I.

    2003-01-01

    A spherical torus (ST) fusion energy development path which is complementary to proposed tokamak burning plasma experiments such as ITER is described. The ST strategy focuses on a compact Component Test Facility (CTF) and higher performance advanced regimes leading to more attractive DEMO and Power Plant scale reactors. To provide the physics basis for the CTF an intermediate step needs to be taken which we refer to as the ''Next Step Spherical Torus'' (NSST) device and examine in some detail herein. NSST is a ''performance extension'' (PE) stage ST with the plasma current of 5-10 MA, R = 1.5 m, and Beta(sub)T less than or equal to 2.7 T with flexible physics capability. The mission of NSST is to: (1) provide a sufficient physics basis for the design of CTF, (2) explore advanced operating scenarios with high bootstrap current fraction/high performance regimes, which can then be utilized by CTF, DEMO, and Power Plants, and (3) contribute to the general plasma/fusion science of high beta toroidal plasmas. The NSST facility is designed to utilize the Tokamak Fusion Test Reactor (or similar) site to minimize the cost and time required for the design and construction

  14. Design innovations of the next-step spherical torus experiment and spherical torus development path

    International Nuclear Information System (INIS)

    Ono, M.; Kessel, C.; Peng, M.

    2003-01-01

    The spherical torus (ST) fusion energy development path is complementary to the tokamak burning plasma experiment such as ITER as it focuses toward the compact Component Test Facility (CTF) and higher toroidal beta regimes to improve the design of DEMO and a Power Plant. To support the ST development path, one option of a Next Step Spherical Torus (NSST) device is examined. NSST is a 'performance extension' (PE) stage ST with a plasma current of 5 - 10 MA, R = 1.5, B T ≤ 2.7 T with flexible physics capability to 1) Provide a sufficient physics basis for the design of the CTF, 2) Explore advanced operating scenarios with high bootstrap current fraction/high performance regimes, which can then be utilized by CTF, DEMO, and Power Plants, 3) Contribute to the general plasma/fusion science of high β toroidal plasmas. The NSST facility is designed to utilize the TFTR site to minimize the cost and time required for the construction. (author)

  15. Next steps in the Energy Frontier - Hadron colliders workshop at LPC@FNAL

    CERN Document Server

    2014-01-01

    With the observation of the Standard Model Higgs boson, the high energy physics community is investigating possible next steps for entering into a new era in particle physics. The aim of this workshop is to bring together physics, instrumentation/detector and accelerator experts to present, outline and discuss all aspects needed for the next steps in the energy frontier. The workshop will focus on the lessons learned with 7 and 8 TeV LHC, physics requirements and subsequent detector technologies for HL-LHC, as well as development needs for future 100 TeV proton collider. The goal is to identify synergies and common approaches where further collaboration between various initiatives could be fruitful. The discovery potential for a future 100 TeV proton collider will depend on the detector / instrumentation capabilities in order to explore the highest energy and phenomena. Many of these detection capabilities will need further studies such as muon detection at several 10s of TeV range, calorimeters capable of me...

  16. Neutronics activities for next generation devices

    International Nuclear Information System (INIS)

    Gohar, Y.

    1985-01-01

    Neutronic activities for the next generation devices are the subject of this paper. The main activities include TFCX and FPD blanket/shield studies, neutronic aspects of ETR/INTOR critical issues, and neutronics computational modules for the tokamak system code and tandem mirror reactor system code. Trade-off analyses, optimization studies, design problem investigations and computational models development for reactor parametric studies carried out for these activities are summarized

  17. General characteristics and assessment of the scientific/technical feasibility of the next major device in the tokamak fusion program. Summary of the US contributions to the INTOR workshop

    International Nuclear Information System (INIS)

    Stacey, W.M. Jr.; Gilleland, J.R.; Kulcinski, G.L.; Rutherford, P.H.

    1979-09-01

    A substantial physics and technology data base for INTOR exists today, and this data base will be expanded over the next few years by currently planned programs. However, certain crucial information will not be developed by currently planned programs. Much of this missing information could be developed on the INTOR time scale by the expansion and/or acceleration of existing R and D programs and by the establishment of new R and D programs. On this basis, it is concluded that it is scientifically and technologically feasible to undertake the construction of an INTOR-like device to operate in the early 1990s, provided that the supporting R and D effort is expanded immediately to provide an adequate data base within the next few years in a few critical areas. Furthermore, it is concluded that the construction of an INTOR-like device to operate in the early 1990s is the appropriate next major step in the development of fusion power

  18. Plasma-material interactions in current tokamaks and their implications for next step fusion reactors

    International Nuclear Information System (INIS)

    Federici, G.; Skinner, C.H.; Brooks, J.N.

    2001-01-01

    The major increase in discharge duration and plasma energy in a next step DT fusion reactor will give rise to important plasma-material effects that will critically in influence its operation, safety and performance. Erosion will increase to a scale of several centimetres from being barely measurable at a micron scale in today's tokamaks. Tritium co-deposited with carbon will strongly affect the operation of machines with carbon plasma facing components. Controlling plasma-wall interactions is critical to achieving high performance in present day tokamaks, and this is likely to continue to be the case in the approach to practical fusion reactors. Recognition of the important consequences of these phenomena stimulated an internationally co-ordinated effort in the part of plasma-surface interactions supporting the Engineering Design Activities of the International Thermonuclear Experimental Reactor project (ITER), and significant progress has been made in better understanding these issues. The paper reviews the underlying physical processes and the existing experimental database of plasma-material inter actions both in tokamaks and laboratory simulation facilities for conditions of direct relevance to next step fusion reactors. Two main topical groups of interaction are considered: (i) erosion/redeposition from plasma sputtering and disruptions, including dust and flake generation and (ii) tritium retention and removal. The use of modelling tools to interpret the experimental results and make projections for conditions expected in future devices is explained. Outstanding technical issues and specific recommendations on potential R and D avenues for their resolution are presented. (author)

  19. Plasma-material interactions in current tokamaks and their implications for next-step fusion reactors

    International Nuclear Information System (INIS)

    Federici, G.; Skinner, C.H.; Brooks, J.N.

    2001-01-01

    The major increase in discharge duration and plasma energy in a next-step DT fusion reactor will give rise to important plasma-material effects that will critically influence its operation, safety and performance. Erosion will increase to a scale of several cm from being barely measurable at a micron scale in today's tokamaks. Tritium co-deposited with carbon will strongly affect the operation of machines with carbon plasma-facing components. Controlling plasma wall interactions is critical to achieving high performance in present-day tokamaks and this is likely to continue to be the case in the approach to practical fusion reactors. Recognition of the important consequences of these phenomena has stimulated an internationally co-ordinated effort in the field of plasma-surface interactions supporting the engineering design activities of the international thermonuclear experimental reactor project (ITER) and significant progress has been made in better understanding these issues. This paper reviews the underlying physical processes and the existing experimental database of plasma-material interactions both in tokamaks and laboratory simulation facilities for conditions of direct relevance to next-step fusion reactors. Two main topical groups of interactions are considered: (i) erosion/re-deposition from plasma sputtering and disruptions, including dust and flake generation, (ii) tritium retention and removal. The use of modelling tools to interpret the experimental results and make projections for conditions expected in future devices is explained. Outstanding technical issues and specific recommendations on potential R and D avenues for their resolution are presented. (orig.)

  20. Preliminary design of a Tandem-Mirror-Next-Step facility

    International Nuclear Information System (INIS)

    Damm, C.C.; Doggett, J.N.; Bulmer, R.H.

    1980-01-01

    The Tandem-Mirror-Next-Step (TMNS) facility is designed to demonstrate the engineering feasibility of a tandem-mirror reactor. The facility is based on a deuterium-tritium (D-T) burning, tandem-mirror device with a fusion power output of 245 MW. The fusion power density in the central cell is 2.1 MW/m 3 , with a resultant neutron wall loading of 0.5 MW/m 2 . Overall machine length is 116 m, and the effective central-cell length is 50.9 m. The magnet system includes end cells with yin-yang magnets to provide magnetohydrodynamic (MHD) stability and thermal-barrier cells to help achieve a plasma Q of 4.7 (where Q = fusion power/injected power). Neutral beams at energies up to 200 keV are used for plasma heating, fueling, and barrier pumping. Electron cyclotron resonant heating at 50 and 100 GHz is used to control the electron temperature in the barriers. Based on the resulting engineering design, the overall cost of the facility is estimated to be just under $1 billion. Unresolved physics issues include central-cell β-limits against MHD ballooning modes (the assumed reference value of β exceeds the current theory-derived limit), and the removal of thermalized α-particles from the plasma

  1. HIGH PERFORMANCE ADVANCED TOKAMAK REGIMES FOR NEXT-STEP EXPERIMENTS

    International Nuclear Information System (INIS)

    GREENFIELD, C.M.; MURAKAMI, M.; FERRON, J.R.; WADE, M.R.; LUCE, T.C.; PETTY, C.C.; MENARD, J.E; PETRIE, T.W.; ALLEN, S.L.; BURRELL, K.H.; CASPER, T.A; DeBOO, J.C.; DOYLE, E.J.; GAROFALO, A.M; GORELOV, Y.A; GROEBNER, R.J.; HOBIRK, J.; HYATT, A.W; JAYAKUMAR, R.J; KESSEL, C.E; LA HAYE, R.J; JACKSON, G.L; LOHR, J.; MAKOWSKI, M.A.; PINSKER, R.I.; POLITZER, P.A.; PRATER, R.; STRAIT, E.J.; TAYLOR, T.S; WEST, W.P.

    2003-01-01

    OAK-B135 Advanced Tokamak (AT) research in DIII-D seeks to provide a scientific basis for steady-state high performance operation in future devices. These regimes require high toroidal beta to maximize fusion output and poloidal beta to maximize the self-driven bootstrap current. Achieving these conditions requires integrated, simultaneous control of the current and pressure profiles, and active magnetohydrodynamic (MHD) stability control. The building blocks for AT operation are in hand. Resistive wall mode stabilization via plasma rotation and active feedback with non-axisymmetric coils allows routine operation above the no-wall beta limit. Neoclassical tearing modes are stabilized by active feedback control of localized electron cyclotron current drive (ECCD). Plasma shaping and profile control provide further improvements. Under these conditions, bootstrap supplies most of the current. Steady-state operation requires replacing the remaining Ohmic current, mostly located near the half-radius, with noninductive external sources. In DIII-D this current is provided by ECCD, and nearly stationary AT discharges have been sustained with little remaining Ohmic current. Fast wave current drive is being developed to control the central magnetic shear. Density control, with divertor cryopumps, of AT discharges with edge localized moding (ELMing) H-mode edges facilitates high current drive efficiency at reactor relevant collisionalities. A sophisticated plasma control system allows integrated control of these elements. Close coupling between modeling and experiment is key to understanding the separate elements, their complex nonlinear interactions, and their integration into self-consistent high performance scenarios. Progress on this development, and its implications for next-step devices, will be illustrated by results of recent experiment and simulation efforts

  2. A Test Device Module of the Step Motor Driver for HANARO CAR Operation

    Energy Technology Data Exchange (ETDEWEB)

    Im, Yun-Taek; Doo, Seung-Gyu; Shin, Jin-Won; Kim, Ki-Hyun; Choi, Young-San; Lee, Jung-Hee; Kim, Hyung-Kyoo; Lee, Choong-Sung [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    The brand-new control system is reliable and has advantages compared with the old control system, and the installed system covers all functional operations of old system. Nevertheless, packaged RTP systems do not include a step motor or driver, and it is necessary to develop a proper test device to check the step motor and driver without using the RTP system. In particular, the operation of a CAR (Control Absorber Rod) requires many complicated procedures. Occasionally, it takes significant time to prepare for a field test. In this work, a test device module for a step motor diver is shown to emulate a HANARO CAR operation, and the test device system architecture, operational principle, and experiment results are presented. A commercial 8-bit μ-processor is applied to implement the device. A portable test device for HANARO CAR operation is presented. An 8-bit μ-controller is used to emulate a HANARO CAR operation. The digital interface, as well as the functional operation, of the test device module matches that of the currently used driver. This device can be used to check the functional validity of the step motor and driver.

  3. Recent progress in nanostructured next-generation field emission devices

    International Nuclear Information System (INIS)

    Mittal, Gaurav; Lahiri, Indranil

    2014-01-01

    Field emission has been known to mankind for more than a century, and extensive research in this field for the last 40–50 years has led to development of exciting applications such as electron sources, miniature x-ray devices, display materials, etc. In the last decade, large-area field emitters were projected as an important material to revolutionize healthcare and medical devices, and space research. With the advent of nanotechnology and advancements related to carbon nanotubes, field emitters are demonstrating highly enhanced performance and novel applications. Next-generation emitters need ultra-high emission current density, high brightness, excellent stability and reproducible performance. Novel design considerations and application of new materials can lead to achievement of these capabilities. This article presents an overview of recent developments in this field and their effects on improved performance of field emitters. These advancements are demonstrated to hold great potential for application in next-generation field emission devices. (topical review)

  4. Recent progress in nanostructured next-generation field emission devices

    Science.gov (United States)

    Mittal, Gaurav; Lahiri, Indranil

    2014-08-01

    Field emission has been known to mankind for more than a century, and extensive research in this field for the last 40-50 years has led to development of exciting applications such as electron sources, miniature x-ray devices, display materials, etc. In the last decade, large-area field emitters were projected as an important material to revolutionize healthcare and medical devices, and space research. With the advent of nanotechnology and advancements related to carbon nanotubes, field emitters are demonstrating highly enhanced performance and novel applications. Next-generation emitters need ultra-high emission current density, high brightness, excellent stability and reproducible performance. Novel design considerations and application of new materials can lead to achievement of these capabilities. This article presents an overview of recent developments in this field and their effects on improved performance of field emitters. These advancements are demonstrated to hold great potential for application in next-generation field emission devices.

  5. Next-Generation Multifunctional Electrochromic Devices.

    Science.gov (United States)

    Cai, Guofa; Wang, Jiangxin; Lee, Pooi See

    2016-08-16

    during the daytime. Energy can also be stored in the smart windows during the daytime simultaneously and be discharged for use in the evening. These results reveal that the electrochromic devices have potential applications in a wide range of areas. We hope that this Account will promote further efforts toward fundamental research on electrochromic materials and the development of new multifunctional electrochromic devices to meet the growing demands for next-generation electronic systems.

  6. Plasma-material Interactions in Current Tokamaks and their Implications for Next-step Fusion Reactors

    International Nuclear Information System (INIS)

    Federici, G.; Skinner, C.H.; Brooks, J.N.; Coad, J.P.; Grisolia, C.

    2001-01-01

    The major increase in discharge duration and plasma energy in a next-step DT (deuterium-tritium) fusion reactor will give rise to important plasma-material effects that will critically influence its operation, safety, and performance. Erosion will increase to a scale of several centimeters from being barely measurable at a micron scale in today's tokamaks. Tritium co-deposited with carbon will strongly affect the operation of machines with carbon plasma-facing components. Controlling plasma wall interactions is critical to achieving high performance in present-day tokamaks and this is likely to continue to be the case in the approach to practical fusion reactors. Recognition of the important consequences of these phenomena has stimulated an internationally coordinated effort in the field of plasma-surface interactions supporting the Engineering Design Activities of the International Thermonuclear Experimental Reactor (ITER) project and significant progress has been made in better under standing these issues. This paper reviews the underlying physical processes and the existing experimental database of plasma-material interactions both in tokamaks and laboratory simulation facilities for conditions of direct relevance to next-step fusion reactors. Two main topical groups of interactions are considered: (i) erosion/redeposition from plasma sputtering and disruptions, including dust and flake generation, (ii) tritium retention and removal. The use of modeling tools to interpret the experimental results and make projections for conditions expected in future devices is explained. Outstanding technical issues and specific recommendations on potential R and D (Research and Development) avenues for their resolution are presented

  7. Plasma-material Interactions in Current Tokamaks and their Implications for Next-step Fusion Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Federici, G.; Skinner, C.H.; Brooks, J.N.; Coad, J.P.; Grisolia, C. [and others

    2001-01-10

    The major increase in discharge duration and plasma energy in a next-step DT [deuterium-tritium] fusion reactor will give rise to important plasma-material effects that will critically influence its operation, safety, and performance. Erosion will increase to a scale of several centimeters from being barely measurable at a micron scale in today's tokamaks. Tritium co-deposited with carbon will strongly affect the operation of machines with carbon plasma-facing components. Controlling plasma wall interactions is critical to achieving high performance in present-day tokamaks and this is likely to continue to be the case in the approach to practical fusion reactors. Recognition of the important consequences of these phenomena has stimulated an internationally coordinated effort in the field of plasma-surface interactions supporting the Engineering Design Activities of the International Thermonuclear Experimental Reactor (ITER) project and significant progress has been made in better under standing these issues. This paper reviews the underlying physical processes and the existing experimental database of plasma-material interactions both in tokamaks and laboratory simulation facilities for conditions of direct relevance to next-step fusion reactors. Two main topical groups of interactions are considered: (i) erosion/redeposition from plasma sputtering and disruptions, including dust and flake generation, (ii) tritium retention and removal. The use of modeling tools to interpret the experimental results and make projections for conditions expected in future devices is explained. Outstanding technical issues and specific recommendations on potential R and D [Research and Development] avenues for their resolution are presented.

  8. Alternative Aviation Fuels: Overview of Challenges, Opportunities, and Next Steps

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2017-03-28

    The Alternative Aviation Fuels: Overview of Challenges, Opportunities, and Next Steps report, published by the U.S. Department of Energy’s Bioenergy Technologies Office (BETO) provides an overview of the current state of alternative aviation fuels, based upon findings from recent peer-reviewed studies, scientific working groups, and BETO stakeholder input provided during the Alternative Aviation Fuel Workshop.

  9. Next Generation, Si-Compatible Materials and Devices in the Si-Ge-Sn System

    Science.gov (United States)

    2015-10-09

    and conclusions The work initially focused on growth of next generation Ge1-ySny alloys on Ge buffered Si wafers via UHV CVD depositions of Ge3H8...Abstract The work initially focused on growth of next generation Ge1-ySny alloys on Ge buffered Si wafers via UHV CVD depositions of Ge3H8, SnD4. The...AFRL-AFOSR-VA-TR-2016-0044 Next generation, Si -compatible materials and devices in the Si - Ge -Sn system John Kouvetakis ARIZONA STATE UNIVERSITY Final

  10. The Scientific Prototype - a proposed next step for the American MFE effort

    Science.gov (United States)

    Manheimer, Wallace

    2013-10-01

    The Scientific prototype is the only logical next step for the American magnetic fusion effort. This poster is divided into two parts. The first is a description of the scientific prototype, a tokamak about the size of TFTR, JET and JT-60, but which runs steady state in DT and breeds its own tritium. The second is an examination of other proposed approaches for American MFE and why none constitute a viable alternative. W. Manheimer, J. Fusion Energy, 32, 419-421, 2013.

  11. Next Place Prediction Based on Spatiotemporal Pattern Mining of Mobile Device Logs.

    Science.gov (United States)

    Lee, Sungjun; Lim, Junseok; Park, Jonghun; Kim, Kwanho

    2016-01-23

    Due to the recent explosive growth of location-aware services based on mobile devices, predicting the next places of a user is of increasing importance to enable proactive information services. In this paper, we introduce a data-driven framework that aims to predict the user's next places using his/her past visiting patterns analyzed from mobile device logs. Specifically, the notion of the spatiotemporal-periodic (STP) pattern is proposed to capture the visits with spatiotemporal periodicity by focusing on a detail level of location for each individual. Subsequently, we present algorithms that extract the STP patterns from a user's past visiting behaviors and predict the next places based on the patterns. The experiment results obtained by using a real-world dataset show that the proposed methods are more effective in predicting the user's next places than the previous approaches considered in most cases.

  12. The six P’s of the next step in electronic patient records in the Netherlands

    NARCIS (Netherlands)

    Michel-Verkerke, Margreet B.; Stegwee, Robert A.; Spil, Antonius A.M.

    2015-01-01

    The objective of this study was to evaluate a decade of Electronic Patient Record development. During the study a second question was added: How to take the next step in the Netherlands? This paper describes the developments but the main results create a framework for the future situation. The USE

  13. Liquid as template for next generation micro devices

    International Nuclear Information System (INIS)

    Charmet, Jerome; Haquette, Henri; Laux, Edith; Keppner, Herbert; Gorodyska, Ganna; Textor, Marcus; Durante, Guido Spinola; Portuondo-Campa, Erwin; Knapp, Helmut; Bitterli, Roland; Noell, Wilfried

    2009-01-01

    Liquids have fascinated generations of scientists and engineers. Since ancient Greece, the perfect natural shape of liquids has been used to create optical systems. Nowadays, the natural shape of liquid is used in the fabrication of microlens arrays that rely on the melting of glass or photoresist to generate high quality lenses. However shrinkage normally associated to the liquid to solid phase transition will affect the initial shape and quality of the liquid structure. In this contribution, a novel fabrication technique that enables the encapsulation and replication of liquid templates without affecting their natural shape is presented. The SOLID (SOlid on LIquid Deposition) process allows for a transparent solid film to be deposited and grown onto a liquid template (droplet, film, line) in a way that the liquid shapes the overgrowing solid layer. The resulting configuration of the SOLID devices is chemically and mechanically stable and is the base of a huge variety of new micro-nano systems in the field of microfluidics, biomedical devices and micro-optics among others. The SOLID process enables in a one step process the encapsulation of liquid microlenses, fluidics channels, drug reservoir or any naturally driven liquid structure. The phenomenon and solid-liquid interface resulting from the SOLID process is new and still unexploited. The solid layer used for the SOLID process chosen in this paper is poly-para-xylylene called Parylene, a transparent biocompatible polymer with excellent mechanical and chemical properties. Moreover, as the solid layer is growing over a liquid template, atomically smooth surfaces channels can be obtained. The polymerization of Parylene does not exert stress and does not change the shape of the liquid; this latter aspect is particularly interesting for manufacturing naturally driven liquid structures. In this paper the authors explore the limits of this new method by testing different designs of SOLID encapsulated structures and

  14. Next Place Prediction Based on Spatiotemporal Pattern Mining of Mobile Device Logs

    Directory of Open Access Journals (Sweden)

    Sungjun Lee

    2016-01-01

    Full Text Available Due to the recent explosive growth of location-aware services based on mobile devices, predicting the next places of a user is of increasing importance to enable proactive information services. In this paper, we introduce a data-driven framework that aims to predict the user’s next places using his/her past visiting patterns analyzed from mobile device logs. Specifically, the notion of the spatiotemporal-periodic (STP pattern is proposed to capture the visits with spatiotemporal periodicity by focusing on a detail level of location for each individual. Subsequently, we present algorithms that extract the STP patterns from a user’s past visiting behaviors and predict the next places based on the patterns. The experiment results obtained by using a real-world dataset show that the proposed methods are more effective in predicting the user’s next places than the previous approaches considered in most cases.

  15. Segmenting the Net-Generation: Embracing the Next Level of Technology

    Science.gov (United States)

    Smith, Russell K.

    2014-01-01

    A segmentation study is used to partition college students into groups that are more or less likely to adopt tablet technology as a learning tool. Because the college population chosen for study presently relies upon laptop computers as their primary learning device, tablet technology represents a "next step" in technology. Student…

  16. Next Steps for "Big Data" in Education: Utilizing Data-Intensive Research

    Science.gov (United States)

    Dede, Chris

    2016-01-01

    Data-informed instructional methods offer tremendous promise for increasing the effectiveness of teaching, learning, and schooling. Yet-to-be-developed data science approaches have the potential to dramatically advance instruction for every student and to enhance learning for people of all ages. Next steps that emerged from a recent National…

  17. Systems Analysis of a Compact Next Step Burning Plasma Experiment

    International Nuclear Information System (INIS)

    Jardin, S.C.; Kessel, C.E.; Meade, D.; Neumeyer, C.

    2002-01-01

    A new burning plasma systems code (BPSC) has been developed for analysis of a next step compact burning plasma experiment with copper-alloy magnet technology. We consider two classes of configurations: Type A, with the toroidal field (TF) coils and ohmic heating (OH) coils unlinked, and Type B, with the TF and OH coils linked. We obtain curves of the minimizing major radius as a function of aspect ratio R(A) for each configuration type for typical parameters. These curves represent, to first order, cost minimizing curves, assuming that device cost is a function of major radius. The Type B curves always lie below the Type A curves for the same physics parameters, indicating that they lead to a more compact design. This follows from that fact that a high fraction of the inner region, r < R-a, contains electrical conductor material. However, the fact that the Type A OH and TF magnets are not linked presents fewer engineering challenges and should lead to a more reliable design. Both the Type A and Type B curves have a minimum in major radius R at a minimizing aspect ratio A typically above 2.8 and at high values of magnetic field B above 10 T. The minimizing A occurs at larger values for longer pulse and higher performance devices. The larger A and higher B design points also have the feature that the ratio of the discharge time to the current redistribution time is largest so that steady-state operation can be more realistically prototyped. A sensitivity study is presented for the baseline Type A configuration showing the dependence of the results on the parameters held fixed for the minimization study

  18. Precision Controlled Carbon Materials for Next-Generation Optoelectronic and Photonic Devices

    Science.gov (United States)

    2018-01-08

    engineer next-generation carbon-based optoelectronic and photonic devices with superior performance and capabilities. These devices include carbon...electronics; (4) nanostructured graphene plasmonics; and (5) polymer-nanotube conjugate chemistry . (1) Semiconducting carbon nanotube-based...applications (In Preparation, 2018). (5) Polymer-nanotube conjugate chemistry Conjugated polymers can be exploited as agents for selectively wrapping and

  19. Development of a Ground Test and Analysis Protocol to Support NASA's NextSTEP Phase 2 Habitation Concepts

    Science.gov (United States)

    Beaton, Kara H.; Chappell, Steven P.; Bekdash, Omar S.; Gernhardt, Michael L.

    2018-01-01

    The NASA Next Space Technologies for Exploration Partnerships (NextSTEP) program is a public-private partnership model that seeks commercial development of deep space exploration capabilities to support extensive human spaceflight missions around and beyond cislunar space. NASA first issued the Phase 1 NextSTEP Broad Agency Announcement to U.S. industries in 2014, which called for innovative cislunar habitation concepts that leveraged commercialization plans for low Earth orbit. These habitats will be part of the Deep Space Gateway (DSG), the cislunar space station planned by NASA for construction in the 2020s. In 2016, Phase 2 of the NextSTEP program selected five commercial partners to develop ground prototypes. A team of NASA research engineers and subject matter experts have been tasked with developing the ground test protocol that will serve as the primary means by which these Phase 2 prototype habitats will be evaluated. Since 2008, this core test team has successfully conducted multiple spaceflight analog mission evaluations utilizing a consistent set of operational products, tools, methods, and metrics to enable the iterative development, testing, analysis, and validation of evolving exploration architectures, operations concepts, and vehicle designs. The purpose of implementing a similar evaluation process for the NextSTEP Phase 2 Habitation Concepts is to consistently evaluate the different commercial partner ground prototypes to provide data-driven, actionable recommendations for Phase 3.

  20. EDITORIAL: Towards the next node in downsized devices Towards the next node in downsized devices

    Science.gov (United States)

    Demming, Anna

    2010-02-01

    Over the past 50 years, one notable trend in the progress of electronics technology has been the steady scaling down in physical size, widely known as Moore's Law. Over the next ten years the ability to continue miniaturizing devices within the existing technological framework faces some fundamental obstacles, and alternatives to traditional CMOS architectures are being investigated. Carbon nanotubes, the wonder material first discovered by Iijima in 1991 [1], have been proposed as a possible means of continuing the trend to down-size devices. This has initiated research into the thermal properties of carbon nanotubes that may affect device performance [2], as well as new synthesis techniques that allow control over the diameter and chirality [3], which are physical characteristics of carbon nanotubes that influence their electronic properties. Carbon nanotubes have been touted as a host of device challenges since their discovery, but an application with truly commercial benefits is yet to be devised. Although the vast potential in carbon nanotube applied research may not yet have tapped into the cashflow from mainstream commerce, the role they have played so far in advancing our understanding of the fundamental properties of systems at the nanoscale remains priceless. Germanium and silicon nanowires are also possible candidates to infiltrate electronic devices. Means of refining fabrication processes and enhancing transport properties in these materials [4, 5] is already a hot topic of research. Electron-beam-induced deposition is one approach that is now widely adopted for fabricating three-dimensional structures for nanoscale devices. However, despite the merits of convenience and versatility, the potential applications of electron-beam-induced deposition are still limited by the problem of impurities introduced by the process. The review published in Nanotechnology [6] at the end of last year presents a user-oriented overview of electron

  1. Global seismic inversion as the next standard step in the processing sequence

    Energy Technology Data Exchange (ETDEWEB)

    Maver, Kim G.; Hansen, Lars S.; Jepsen, Anne-Marie; Rasmussen, Klaus B.

    1998-12-31

    Seismic inversion of post stack seismic data has until recently been regarded as a reservoir oriented method since the standard inversion techniques rely on extensive well control and a detailed user derived input model. Most seismic inversion techniques further requires a stable wavelet. As a consequence seismic inversion is mainly utilised in mature areas focusing of specific zones only after the seismic data has been interpreted and is well understood. By using an advanced 3-D global technique, seismic inversion is presented as the next standard step in the processing sequence. The technique is robust towards noise within the seismic data, utilizes a time variant wavelet, and derives a low frequency model utilizing the stacking velocities and only limited well control. 4 figs.

  2. The FREYA project at VENUS-F - the next step towards MYRRHA

    Energy Technology Data Exchange (ETDEWEB)

    Krasa, A.; Baeten, P.; Kochetkov, A.; Uyttenhove, W.; Vittiglio, G.; Wagemans, J. [SCK.CEN, Boeretang 200, 2400 Mol (Belgium); Mercatali, L. [Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen (Germany); Bianchini, G.; Carta, M.; Fabrizio, V.; Peluso, V. [ENEA, C.R. Casaccia, via Anguillarese, 301-00060 S. Maria di Galeria (Italy)

    2015-07-01

    number of in-pile sections and heterogeneous elements inside and around the active zone, the next cores will be step by step modified by loading new materials and perturbations with the aim to assemble a MYRRHA mock-up. (authors)

  3. Time to pause before the next step

    International Nuclear Information System (INIS)

    Siemon, R.E.

    1998-01-01

    Many scientists, who have staunchly supported ITER for years, are coming to realize it is time to further rethink fusion energy's development strategy. Specifically, as was suggested by Grant Logan and Dale Meade, and in keeping with the restructuring of 1996, a theme of better, cheaper, faster fusion would serve the program more effectively than ''demonstrating controlled ignition...and integrated testing of the high-heat-flux and nuclear components required to utilize fusion energy...'' which are the important ingredients of ITER's objectives. The author has personally shifted his view for a mixture of technical and political reasons. On the technical side, he senses that through advanced tokamak research, spherical tokamak research, and advanced stellarator work, scientists are coming to a new understanding that might make a burning-plasma device significantly smaller and less expensive. Thus waiting for a few years, even ten years, seems prudent. Scientifically, there is fascinating physics to be learned through studies of burning plasma on a tokamak. And clearly if one wishes to study burning plasma physics in a sustained plasma, there is no other configuration with an adequate database on which to proceed. But what is the urgency of moving towards an ITER-like step focused on burning plasma? Some of the arguments put forward and the counter arguments are discussed here

  4. Potential Next Steps for the New Orleans City Council Energy Efficiency Resolution

    Energy Technology Data Exchange (ETDEWEB)

    Doris, E.

    2011-09-01

    This document is adapted from an actual February 2008 deliverable memo and report delivered by the National Renewable Energy Laboratory (NREL) to the City Council of New Orleans, the office of the Mayor of New Orleans, the Chairperson of the Citizen Stakeholders Group (New Orleans Energy Task Force) and the Department of Energy Project Officer in February of 2008. In January 2008, the New Orleans Utility Committee requested review, commentary, and suggestions for Utility Committee next steps related to the Energy Efficiency Resolution (the Resolution) passed by the City Council in December 2007. The suggestions are reprinted here as: (1) An illustration of opportunities for other local governments for the development and implementation of effective energy efficiency ordinances and resolutions; and (2) An example of the type of policy technical assistance that DOE/NREL provides to communities. For more information on the strategy for delivering assistance, please see: www.nrel.gov/docs/fy11osti/48689.pdf. Based on experience in other communities and energy efficiency policies and programs, NREL found the Resolution to be a solid framework for increasing the responsible use of energy efficiency and reaping the associated economic and environmental benefits in the city of New Orleans. The remainder of this document provides the requested suggestions for next steps in implementing the word and spirit of the resolution. These suggestions integrate the extensive work of other entities, including the New Orleans Mayor's office, the New Orleans Energy Advisory Committee, the Energy Efficiency Initiative, and the U.S. Environmental Protection Agency's National Action Plan for Energy Efficiency. In general, three actions were suggested for funding mechanisms, two for near-term successes, and two for longer-term success.

  5. Free Modal Algebras Revisited: The Step-by-Step Method

    NARCIS (Netherlands)

    Bezhanishvili, N.; Ghilardi, Silvio; Jibladze, Mamuka

    2012-01-01

    We review the step-by-step method of constructing finitely generated free modal algebras. First we discuss the global step-by-step method, which works well for rank one modal logics. Next we refine the global step-by-step method to obtain the local step-by-step method, which is applicable beyond

  6. Agroforestry—The Next Step in Sustainable and Resilient Agriculture

    Directory of Open Access Journals (Sweden)

    Matthew Heron Wilson

    2016-06-01

    Full Text Available Agriculture faces the unprecedented task of feeding a world population of 9 billion people by 2050 while simultaneously avoiding harmful environmental and social effects. One effort to meet this challenge has been organic farming, with outcomes that are generally positive. However, a number of challenges remain. Organic yields lag behind those in conventional agriculture, and greenhouse gas emissions and nutrient leaching remain somewhat problematic. In this paper, we examine current organic and conventional agriculture systems and suggest that agroforestry, which is the intentional combination of trees and shrubs with crops or livestock, could be the next step in sustainable agriculture. By implementing systems that mimic nature’s functions, agroforestry has the potential to remain productive while supporting a range of ecosystem services. In this paper, we outline the common practices and products of agroforestry as well as beneficial environmental and social effects. We address barriers to agroforestry and explore potential options to alter policies and increase adoption by farmers. We conclude that agroforestry is one of the best land use strategies to contribute to food security while simultaneously limiting environmental degradation.

  7. Energy market reform - lessons learned and next steps

    International Nuclear Information System (INIS)

    Doucet, G.

    2004-01-01

    This presentation will be based on the World Energy Council's recently published report, Energy Market Reform: Lessons Learned and Next Steps with Special Emphasis on the Energy Access Problems of Developing Countries. The report draws on practical lessons from past studies carried out by the World Energy Council and on current experiences on the desirable architecture of market reforms in electricity and natural gas. The approach of the study was not to further deepen the analysis or to provide technical recommendations but rather, to build a debate guided by the common thread of energy security and end-user e mpowerment , highlighting the possible areas of conflict of interest and the broad solutions that might be chosen depending on the local circumstances for different parts of the energy chains. The ambition was to identify key concerns and to initiate a debate on possible answers.(author)

  8. Serious Games for Health: Features, Challenges, Next Steps.

    Science.gov (United States)

    Blumberg, Moderators Fran C; Burke, Lauren C; Hodent, Participants Celia; Evans, Michael A; Lane, H Chad; Schell, Jesse

    2014-10-01

    As articles in this journal have demonstrated over the past 3 years, serious game development continues to flourish as a vehicle for formal and informal health education. How best to characterize a "serious" game remains somewhat elusive in the literature. Many researchers and practitioners view serious games as capitalizing on computer technology and state-of-the-art video graphics as an enjoyable means by which to provide and promote instruction and training, or to facilitate attitude change among its players. We invited four distinguished researchers and practitioners to further discuss with us how they view the characteristics of serious games for health, how those characteristics differ from those for academic purposes, the challenges posed for serious game development among players of different ages, and next steps for the development and empirical examination of the effectiveness of serious games for players' psychological and physical well-being.

  9. Emerging technologies to power next generation mobile electronic devices using solar energy

    Institute of Scientific and Technical Information of China (English)

    Dewei JIA; Yubo DUAN; Jing LIU

    2009-01-01

    Mobile electronic devices such as MP3, mobile phones, and wearable or implanted medical devices have already or will soon become a necessity in peoples' lives.However, the further development of these devices is restricted not only by the inconvenient charging process of the power module, but also by the soaring prices of fossil fuel and its downstream chain of electricity manipulation.In view of the huge amount of solar energy fueling the world biochemically and thermally, a carry-on electricity harvester embedded in portable devices is emerging as a most noteworthy research area and engineering practice for a cost efficient solution. Such a parasitic problem is intrinsic in the next generation portable devices. This paper is dedicated to presenting an overview of the photovoltaic strategy in the chain as a reference for researchers and practitioners committed to solving the problem.

  10. A two-step annealing process for enhancing the ferroelectric properties of poly(vinylidene fluoride) (PVDF) devices

    KAUST Repository

    Park, Jihoon; Kurra, Narendra; AlMadhoun, M. N.; Odeh, Ihab N.; Alshareef, Husam N.

    2015-01-01

    We report a simple two-step annealing scheme for the fabrication of stable non-volatile memory devices employing poly(vinylidene fluoride) (PVDF) polymer thin-films. The proposed two-step annealing scheme comprises the crystallization

  11. Comparison between a pumped-limiter and a divertor for the next step machines

    International Nuclear Information System (INIS)

    Harrison, F.F.A.

    1985-01-01

    The paper presents a simple description of the physics issues which influence the conceptual design of a pumped-limiter and single-null poloidal divertor in a next step, long burn tokamak of NET/INTOR scale. Predicted performance of the limiter and divertor are compared in regard to localised recycling, sputtering of the plasma collection surfaces, penetration of sputtered impurities into the fusion plasma, surface power loading and exhaust of helium ash. It is concluded that the performance of the divertor is superior and that it can be predicted with a reasonable degree of confidence. The viability of the limiter remains in doubt but the concept cannot be rejected at the present time

  12. Implications of rf current drive theory for next step steady-state tokamak design

    International Nuclear Information System (INIS)

    Schultz, J.H.

    1985-06-01

    Two missions have been identified for a next-step tokamak experiment in the United States. The more ambitious Mission II device would be a superconducting tokamak, capable of doing long-pulse ignition demonstrations, and hopefully capable of also being able to achieve steady-state burn. A few interesting lines of approach have been identified, using a combination of logical design criteria and parametric system scans [SC85]. These include: (1) TIBER: A point-design suggested by Lawrence Livermore, that proposes a machine with the capability of demonstrating ignition, high beta (10%) and high Q (=10), using high frequency, fast-wave current drive. The TIBER topology uses moderate aspect ratio and high triangularity to achieve high beta. (2) JET Scale-up. (3) Magic5: It is argued here that an aspect ratio of 5 is a magic number for a good steady-state current drive experiment. A moderately-sized machine that achieves ignition and is capable of high Q, using either fast wave or slow wave current drive is described. (4) ET-II: The concept of a highly elongated tokamak (ET) was first proposed as a low-cost approach to Mission I, because of the possibility of achieving ohmic ignition with low-stress copper magnets. We propose that its best application is really for commercial tokamaks, using fast-wave current drive, and suggest a Mission II experiment that would be prototypical of such a reactor

  13. Group Health Coaching: Strengths, Challenges, and Next Steps

    Science.gov (United States)

    Wolever, Ruth Q.; Manning, Linda; Elam, Roy; Moore, Margaret; Frates, Elizabeth Pegg; Duskey, Heidi; Anderson, Chelsea; Curtis, Rebecca L.; Masemer, Susan; Lawson, Karen

    2013-01-01

    There is great need for cost effective approaches to increase patient engagement and improve health and well-being. Health and wellness coaching has recently demonstrated great promise, but the majority of studies to date have focused on individual coaching (ie, one coach with one client). Newer initiatives are bringing a group coaching model from corporate leadership development and educational settings into the healthcare arena. A group approach potentially increases cost-effective access to a larger number of clients and brings the possible additional benefit of group support. This article highlights some of the group coaching approaches currently being conducted across the United States. The group coaching interventions included in this overview are offered by a variety of academic and private sector institutions, use both telephonic and in-person coaching, and are facilitated by professionally trained health and wellness coaches as well as trained peer coaches. Strengths and challenges experienced in these efforts are summarized, as are recommendations to address those challenges. A working definition of “Group Health and Wellness Coaching” is proposed, and important next steps for research and for the training of group coaches are presented. PMID:24416678

  14. Group health coaching: strengths, challenges, and next steps.

    Science.gov (United States)

    Armstrong, Colin; Wolever, Ruth Q; Manning, Linda; Elam, Roy; Moore, Margaret; Frates, Elizabeth Pegg; Duskey, Heidi; Anderson, Chelsea; Curtis, Rebecca L; Masemer, Susan; Lawson, Karen

    2013-05-01

    There is great need for cost effective approaches to increase patient engagement and improve health and well-being. Health and wellness coaching has recently demonstrated great promise, but the majority of studies to date have focused on individual coaching (ie, one coach with one client). Newer initiatives are bringing a group coaching model from corporate leadership development and educational settings into the healthcare arena. A group approach potentially increases cost-effective access to a larger number of clients and brings the possible additional benefit of group support. This article highlights some of the group coaching approaches currently being conducted across the United States. The group coaching interventions included in this overview are offered by a variety of academic and private sector institutions, use both telephonic and in-person coaching, and are facilitated by professionally trained health and wellness coaches as well as trained peer coaches. Strengths and challenges experienced in these efforts are summarized, as are recommendations to address those challenges. A working definition of "Group Health and Wellness Coaching" is proposed, and important next steps for research and for the training of group coaches are presented.

  15. Evening electronic device use: The effects on alertness, sleep and next-day physical performance in athletes.

    Science.gov (United States)

    Jones, Maddison J; Peeling, Peter; Dawson, Brian; Halson, Shona; Miller, Joanna; Dunican, Ian; Clarke, Michael; Goodman, Carmel; Eastwood, Peter

    2018-01-01

    The aim of the present study was to investigate the influence of different types of tasks performed with or without an electronic device (tablet) on pre-sleep alertness, subsequent sleep quality and next-day athletic performance. Eight highly trained netball players attended a sleep laboratory for pre-sleep testing, polysomnographic sleep monitoring and next-day physical performance testing on 5 separate occasions (1 familiarisation and 4 experimental sessions). For 2 h prior to bedtime, athletes completed cognitively stimulating tasks (puzzles) or passive tasks (reading) with or without a tablet. Sleepiness tended to be greater after reading compared to completing puzzles without a tablet (d = 0.80), but not with a tablet. Melatonin concentration increased more so after reading compared to completing puzzles on a tablet (P = 0.02). There were no significant differences in sleep quality or quantity or next-day athletic performance between any of the conditions. These data suggest that using a tablet for 2 h prior to sleep does not negatively affect subsequent sleep or next-day performance in athletes.

  16. Spin-charge-family theory is offering next step in understanding elementary particles and fields and correspondingly universe

    International Nuclear Information System (INIS)

    Mankoč Borštnik, Norma Susana

    2017-01-01

    More than 40 years ago the standard model made a successful new step in understanding properties of fermion and boson fields. Now the next step is needed, which would explain what the standard model and the cosmological models just assume: a. The origin of quantum numbers of massless one family members. b. The origin of families. c. The origin of the vector gauge fields. d. The origin of the Higgses and Yukawa couplings. e. The origin of the dark matter. f. The origin of the matter-antimatter asymmetry. g. The origin of the dark energy. h. And several other open problems. The spin-charge-family theory, a kind of the Kaluza-Klein theories in ( d = (2 n − 1) + 1)-space-time, with d = (13 + 1) and the two kinds of the spin connection fields, which are the gauge fields of the two kinds of the Clifford algebra objects anti-commuting with one another, may provide this much needed next step. The talk presents: i. A short presentation of this theory. ii. The review over the achievements of this theory so far, with some not published yet achievements included. iii. Predictions for future experiments. (paper)

  17. Spin-charge-family theory is offering next step in understanding elementary particles and fields and correspondingly universe

    Science.gov (United States)

    Mankoč Borštnik, Norma Susana

    2017-05-01

    More than 40 years ago the standard model made a successful new step in understanding properties of fermion and boson fields. Now the next step is needed, which would explain what the standard model and the cosmological models just assume: a. The origin of quantum numbers of massless one family members. b. The origin of families. c. The origin of the vector gauge fields. d. The origin of the Higgses and Yukawa couplings. e. The origin of the dark matter. f. The origin of the matter-antimatter asymmetry. g. The origin of the dark energy. h. And several other open problems. The spin-charge-family theory, a kind of the Kaluza-Klein theories in (d = (2n - 1) + 1)-space-time, with d = (13 + 1) and the two kinds of the spin connection fields, which are the gauge fields of the two kinds of the Clifford algebra objects anti-commuting with one another, may provide this much needed next step. The talk presents: i. A short presentation of this theory. ii. The review over the achievements of this theory so far, with some not published yet achievements included. iii. Predictions for future experiments.

  18. Usability of an internet-based platform (Next.Step for adolescent weight management

    Directory of Open Access Journals (Sweden)

    Pedro Sousa

    2015-02-01

    Full Text Available OBJECTIVE: The current study evaluates the usability perception of an e-therapeutic platform (supported by electronic processes and communication, aiming to promote the behavior change and to improve the adolescent health status through increased and interactive contact between the adolescent and the clinical staff. METHODS: This was a correlational study with a sample of 48 adolescents (12-18 years who attended a Pediatric Obesity Clinic between January and August of 2012. Participants were invited to access, during 24 weeks, the e-therapeutic multidisciplinary platform (Next.Step in addition to the standard treatment program. A usability questionnaire was administered and the platform performance and utilization indicators were analyzed. RESULTS: The users' perception of satisfaction, efficiency, and effectiveness regarding the Next.Step platform was clearly positive. However, only 54.17% of the enrolled adolescents accessed the platform, with a mean task-completion rate of 14.55% (SD = 18.853. The higher the number of the platform consulted resources, the greater the tendency to enjoy the platform, to consider it exciting and quick, to consider that the time spent in it was useful, to consider the access to information easy, and to login easier. Post-intervention assessment revealed a significant reduction in anthropometric and behavioral variables, including body mass index z-score, waist circumference percentile, hip circumference, and weekly screen time. CONCLUSION: These results highlight the importance of information and communication technologies in the health information access and the healthcare provision. Despite the limited adherence rate, platform users expressed a positive overall perception of its usability and presented a positive anthropometric and behavioral progress.

  19. Final repository searching in Germany - what are the next steps?; Endlagerstandortsuche in Deutschland. Wie geht's weiter?

    Energy Technology Data Exchange (ETDEWEB)

    Neles, Julia Mareike [Oeko-Institut e.V., Darmstadt (Germany). Bereich Nukleartechnik und Anlagensicherheit

    2016-07-01

    Up to now (2016) the question of final disposal of high-level radioactive wastes is still open in Germany. The Commission of radioactive waste disposal has finalized its report including recommendations for the further process. The next step will be the site selection procedure based on a ''white map''. The protest of several Federal states and communities against repository sites in their region is already developing.

  20. A two-step annealing process for enhancing the ferroelectric properties of poly(vinylidene fluoride) (PVDF) devices

    KAUST Repository

    Park, Jihoon

    2015-01-01

    We report a simple two-step annealing scheme for the fabrication of stable non-volatile memory devices employing poly(vinylidene fluoride) (PVDF) polymer thin-films. The proposed two-step annealing scheme comprises the crystallization of the ferroelectric gamma-phase during the first step and enhancement of the PVDF film dense morphology during the second step. Moreover, when we extended the processing time of the second step, we obtained good hysteresis curves down to 1 Hz, the first such report for ferroelectric PVDF films. The PVDF films also exhibit a coercive field of 113 MV m-1 and a ferroelectric polarization of 5.4 μC cm-2. © The Royal Society of Chemistry 2015.

  1. Next Steps: Water Technology Advances (Research)

    Science.gov (United States)

    This project will focus on contaminants and their impact on health, adequate removal of contaminants from various water systems, and water and resource recovery within treatment systems. It will develop the next generation of technological advances to provide guidance in support ...

  2. Elise - the next step in development of induction heavy ion drivers for inertial fusion energy

    International Nuclear Information System (INIS)

    Lee, E.; Bangerter, R.O.; Celata, C.; Faltens, A.; Fessenden, T.; Peters, C.; Pickrell, J.; Reginato, L.; Seidl, P.; Yu, S.

    1994-11-01

    LBL, with the participation of LLNL and industry, proposes to build Elise, an electric-focused accelerator as the next logical step towards the eventual goal of a heavy-ion induction linac powerful enough to implode or open-quotes driveclose quotes inertial-confinement fusion targets. Elise will be at full driver scale in several important parameters-most notably line charge density (a function of beam size), which was not explored in earlier experiments. Elise will be capable of accelerating and electrostatically focusing four parallel, full-scale ion beams and will be designed to be extendible, by successive future construction projects, to meet the goal of the USA DOE Inertial Fusion Energy program (IFE). This goal is to address all remaining issues in heavy-ion IFE except target physics, which is currently the responsibility of DOE Defense Programs, and the target chamber. Thus Elise is the first step of a program that will provide a solid foundation of data for further progress toward a driver, as called for in the National Energy Strategy and National Energy Policy Act

  3. Novel cancer immunotherapy agents with survival benefit: recent successes and next steps

    Science.gov (United States)

    Sharma, Padmanee; Wagner, Klaus; Wolchok, Jedd D.; Allison, James P.

    2012-01-01

    The US Food and Drug Administration (FDA) recently approved two novel immunotherapy agents, sipuleucel-T and ipilimumab, which showed a survival benefit for patients with metastatic prostate cancer and melanoma, respectively. The mechanisms by which these agents provide clinical benefit are not completely understood. However, knowledge of these mechanisms will be crucial for probing human immune responses and tumour biology in order to understand what distinguishes responders from non-responders. The following next steps are necessary: first, the development of immune-monitoring strategies for the identification of relevant biomarkers; second, the establishment of guidelines for the assessment of clinical end points; and third, the evaluation of combination therapy strategies to improve clinical benefit. PMID:22020206

  4. Institutionalizing policy-level health impact assessment in Europe: is coupling health impact assessment with strategic environmental assessment the next step forward?

    Science.gov (United States)

    Wright, John; Parry, Jayne; Scully, Edward

    2005-06-01

    European Union (EU) Member States are interested in using health impact assessment (HIA) as a means of safeguarding their obligations to protect human health under the 1997 Treaty of Amsterdam. However, several have encountered difficulties institutionalizing HIA with the policy-making process. As a consequence, the World Health Organization (WHO) Regional Office for Europe has suggested coupling HIA with strategic environmental assessment (SEA). Traditionally, the incorporation of HIA into other forms of impact assessment has been resisted, for fear of losing its focus on health issues to environmental concerns, and compromising its social model of health with the introduction of biophysical indicators. But can these fears be substantiated? In this paper, we investigate the grounds for such concerns by reviewing the relevant policy documents and departmental guidelines of four non-European countries that have considered the use of integrated assessment. We found that the case for associating HIA with SEA in Europe is strong, and offers potential solutions to problems of screening, theoretical framework, causal pathways and ready entry to the policy process. Coupling HIA with SEA may thus be the next step forward in a longer journey towards institutionalizing HIA as an independent policy-linked device.

  5. Proceedings of 1999 U.S./Japan Workshop (99FT-05) On High Heat Flux Components and Plasma Surface Interactions for Next Fusion Devices

    International Nuclear Information System (INIS)

    NYGREN, RICHARD E.; STAVROS, DIANA T.

    2000-01-01

    The 1999 US-Japan Workshop on High Heat Flux Components and Plasma Surface Interactions in Next Step Fusion Devices was held at the St. Francis Hotel in Santa Fe, New Mexico, on November 1-4, 1999. There were 42 presentations as well as discussion on technical issues and planning for future collaborations. The participants included 22 researchers from Japan and the United States as well as seven researchers from Europe and Russia. There have been important changes in the programs in both the US and Japan in the areas of plasma surface interactions and plasma facing components. The US has moved away from a strong focus on the ITER Project and has introduced new programs on use of liquid surfaces for plasma facing components, and operation of NSTX has begun. In Japan, the Large Helical Device began operation. This is the first large world-class confinement device operating in a magnetic configuration different than a tokamak. In selecting the presentations for this workshop, the organizers sought a balance between research in laboratory facilities or confinement devices related to plasma surface interactions and experimental research in the development of plasma facing components. In discussions about the workshop itself, the participants affirmed their preference for a setting where ''work-in-progress'' could be informally presented and discussed

  6. Development of a Ground Test and Analysis Protocol for NASA's NextSTEP Phase 2 Habitation Concepts

    Science.gov (United States)

    Gernhardt, Michael L.; Beaton, Kara H.; Chappell, Steven P.; Bekdash, Omar S.; Abercromby, Andrew F. J.

    2018-01-01

    The NASA Next Space Technologies for Exploration Partnerships (NextSTEP) program is a public-private partnership model that seeks commercial development of deep space exploration capabilities to support human spaceflight missions around and beyond cislunar space. NASA first issued the Phase 1 NextSTEP Broad Agency Announcement to U.S. industries in 2014, which called for innovative cislunar habitation concepts that leveraged commercialization plans for low-Earth orbit. These habitats will be part of the Deep Space Gateway (DSG), the cislunar space station planned by NASA for construction in the 2020s. In 2016, Phase 2 of the NextSTEP program selected five commercial partners to develop ground prototypes. A team of NASA research engineers and subject matter experts (SMEs) have been tasked with developing the ground-test protocol that will serve as the primary means by which these Phase 2 prototypes will be evaluated. Since 2008, this core test team has successfully conducted multiple spaceflight analog mission evaluations utilizing a consistent set of operational tools, methods, and metrics to enable the iterative development, testing, analysis, and validation of evolving exploration architectures, operations concepts, and vehicle designs. The purpose of implementing a similar evaluation process for the Phase 2 Habitation Concepts is to consistently evaluate different commercial partner ground prototypes to provide data-driven, actionable recommendations for Phase 3. This paper describes the process by which the ground test protocol was developed and the objectives, methods, and metrics by which the NextSTEP Phase 2 Habitation Concepts will be rigorously and systematically evaluated. The protocol has been developed using both a top-down and bottom-up approach. Top-down development began with the Human Exploration and Operations Mission Directorate (HEOMD) exploration objectives and ISS Exploration Capability Study Team (IECST) candidate flight objectives. Strategic

  7. The next generation mass storage devices - Physical principles and current status

    Science.gov (United States)

    Wang, L.; Gai, S.

    2014-04-01

    The amount of digital data today has been increasing at a phenomenal rate due to the widespread digitalisation service in almost every industry. The need to store such ever-increasing data aggressively triggers the requirement to augment the storage capacity of the conventional storage technologies. Unfortunately, the physical limitations that conventional forms face have severely handicapped their potential to meet the storage need from both consumer and industry point of view. The focus has therefore been switched into the development of the innovative data storage technologies such as scanning probe memory, nanocrystal memory, carbon nanotube memory, DNA memory, and organic memory. In this paper, we review the physical principles of these emerging storage technologies and their superiorities as the next generation data storage device, as well as their respective technical challenges on further enhancing the storage capacity. We also compare these novel technologies with the mainstream data storage means according to the technology roadmap on areal density.

  8. Epilepsy Forewarning Using A Hand-Held Device

    Energy Technology Data Exchange (ETDEWEB)

    Hively, LM

    2005-02-21

    Over the last decade, ORNL has developed and patented a novel approach for forewarning of a large variety of machine and biomedical events. The present implementation uses desktop computers to analyze archival data. This report describes the next logical step in this effort, namely use of a hand-held device for the analysis.

  9. Reaching the Next Generation of College Students via Their Digital Devices.

    Science.gov (United States)

    Whitmeyer, S. J.; De Paor, D. G.; Bentley, C.

    2015-12-01

    Current college students attended school during a decade in which many school districts banned cellphones from the classroom or even from school grounds. These students are used to being told to put away their mobile devices and concentrate on traditional classroom activities such as watching PowerPoint presentations or calculating with pencil and paper. However, due to a combination of parental security concerns and recent education research, schools are rapidly changing policy and embracing mobile devices for ubiquitous learning opportunities inside and outside of the classroom. Consequently, many of the next generation of college students will have expectations of learning via mobile technology. We have developed a range of digital geology resources to aid mobile-based geoscience education at college level, including mapping on iPads and other tablets, "crowd-sourced" field projects, augmented reality-supported asynchronous field classes, 3D and 4D split-screen virtual reality tours, macroscopic and microscopic gigapixel imagery, 360° panoramas, assistive devices for inclusive field education, and game-style educational challenges. Class testing of virtual planetary tours shows modest short-term learning gains, but more work is needed to ensure long-term retention. Many of our resources rely on the Google Earth browser plug-in and application program interface (API). Because of security concerns, browser plug-ins in general are being phased out and the Google Earth API will not be supported in future browsers. However, a new plug-in-free API is promised by Google and an alternative open-source virtual globe called Cesium is undergoing rapid development. It already supports the main aspects of Keyhole Markup Language and has features of significant benefit to geoscience, including full support on mobile devices and sub-surface viewing and touring. The research team includes: Heather Almquist, Stephen Burgin, Cinzia Cervato, Filis Coba, Chloe Constants, Gene

  10. Estimating heterotrophic respiration at large scales: Challenges, approaches, and next steps

    Science.gov (United States)

    Bond-Lamberty, Ben; Epron, Daniel; Harden, Jennifer W.; Harmon, Mark E.; Hoffman, Forrest; Kumar, Jitendra; McGuire, Anthony David; Vargas, Rodrigo

    2016-01-01

    Heterotrophic respiration (HR), the aerobic and anaerobic processes mineralizing organic matter, is a key carbon flux but one impossible to measure at scales significantly larger than small experimental plots. This impedes our ability to understand carbon and nutrient cycles, benchmark models, or reliably upscale point measurements. Given that a new generation of highly mechanistic, genomic-specific global models is not imminent, we suggest that a useful step to improve this situation would be the development of “Decomposition Functional Types” (DFTs). Analogous to plant functional types (PFTs), DFTs would abstract and capture important differences in HR metabolism and flux dynamics, allowing modelers and experimentalists to efficiently group and vary these characteristics across space and time. We argue that DFTs should be initially informed by top-down expert opinion, but ultimately developed using bottom-up, data-driven analyses, and provide specific examples of potential dependent and independent variables that could be used. We present an example clustering analysis to show how annual HR can be broken into distinct groups associated with global variability in biotic and abiotic factors, and demonstrate that these groups are distinct from (but complementary to) already-existing PFTs. A similar analysis incorporating observational data could form the basis for future DFTs. Finally, we suggest next steps and critical priorities: collection and synthesis of existing data; more in-depth analyses combining open data with rigorous testing of analytical results; using point measurements and realistic forcing variables to constrain process-based models; and planning by the global modeling community for decoupling decomposition from fixed site data. These are all critical steps to build a foundation for DFTs in global models, thus providing the ecological and climate change communities with robust, scalable estimates of HR.

  11. Step edge Josephson junctions and high temperature superconducting quantum interference device (SQUID) gradiometers

    International Nuclear Information System (INIS)

    Millar, Alasdair J.

    2002-01-01

    This thesis is concerned with the development of Superconducting Quantum Interference Device (SQUID) gradiometers based on the high temperature superconductor YBa 2 Cu 3 O 7-δ (YBCO). A step-edge Josephson junction fabrication process was developed to produce sufficiently steep (>60 deg) step-edges such that junctions exhibited RSJ-like current-voltage characteristics. The mean I C R N product of a sample of twenty step-edge junctions was 130μV. Step-edge dc SQUIDs with inductances between 67pH and 114pH were fabricated. Generally the SQUIDs had an intrinsic white flux noise in the 10-30μΦ 0 /√Hz range, with the best device, a 70pH SQUID, exhibiting a white flux noise of 5μΦ 0 /√Hz. Different first-order SQUID gradiometer designs were fabricated from single layers of YBCO. Two single-layer gradiometer (SLG) designs were fabricated on 10x10mm 2 substrates. The best balance and lowest gradient sensitivity measured for these devices were 1/300 and 308fT/cm√Hz (at 1 kHz) respectively. The larger baseline and larger flux capture area of the pick-up loops in a large area SLG design, fabricated on 30x10mm 2 substrates, resulted in significant improvements in the balance and gradient field sensitivity with 1/1000 and 50fT/cm√Hz (at 1kHz) measured respectively. To reduce the uniform field effective area of SLOs and therefore reduce the direct pick-up of environmental field noise when operated unshielded, a novel gradiometric SQUID (G-SQUID) device was developed. Fabricated from a single layer of YBCO, the G-SQUIDs with inductances of 67pH, had small uniform field effective areas of approximately 2μm 2 - more than two orders of magnitude smaller than the uniform field effective areas of conventional narrow linewidth SQUIDs of similar inductance. Two designs of G-SQUID were fabricated on 10x10mm 2 substrates. Due to their small effective areas, when cooled unshielded these devices showed no increase in their white flux noise. The best balance achieved for a G

  12. Optoelectronic devices, low temperature preparation methods, and improved electron transport layers

    KAUST Repository

    Eita, Mohamed S.

    2016-08-04

    An optoelectronic device such as a photovoltaic device which has at least one layer, such as an electron transport layer, which comprises a plurality of alternating, oppositely charged layers including metal oxide layers. The metal oxide can be zinc oxide. The plurality of layers can be prepared by layer-by-layer processing in which alternating layers are built up step-by-step due to electrostatic attraction. The efficiency of the device can be increased by this processing method compared to a comparable method like sputtering. The number of layers can be controlled to improve device efficiency. Aqueous solutions can be used which is environmentally friendly. Annealing can be avoided. A quantum dot layer can be used next to the metal oxide layer to form a quantum dot heterojunction solar device.

  13. Multi-step resistive switching behavior of Li-doped ZnO resistance random access memory device controlled by compliance current

    International Nuclear Information System (INIS)

    Lin, Chun-Cheng; Tang, Jian-Fu; Su, Hsiu-Hsien; Hong, Cheng-Shong; Huang, Chih-Yu; Chu, Sheng-Yuan

    2016-01-01

    The multi-step resistive switching (RS) behavior of a unipolar Pt/Li 0.06 Zn 0.94 O/Pt resistive random access memory (RRAM) device is investigated. It is found that the RRAM device exhibits normal, 2-, 3-, and 4-step RESET behaviors under different compliance currents. The transport mechanism within the device is investigated by means of current-voltage curves, in-situ transmission electron microscopy, and electrochemical impedance spectroscopy. It is shown that the ion transport mechanism is dominated by Ohmic behavior under low electric fields and the Poole-Frenkel emission effect (normal RS behavior) or Li + ion diffusion (2-, 3-, and 4-step RESET behaviors) under high electric fields.

  14. Proceedings of 1999 U.S./Japan Workshop (99FT-05) On High Heat Flux Components and Plasma Surface Interactions for Next Fusion Devices

    Energy Technology Data Exchange (ETDEWEB)

    NYGREN,RICHARD E.; STAVROS,DIANA T.

    2000-06-01

    The 1999 US-Japan Workshop on High Heat Flux Components and Plasma Surface Interactions in Next Step Fusion Devices was held at the St. Francis Hotel in Santa Fe, New Mexico, on November 1-4, 1999. There were 42 presentations as well as discussion on technical issues and planning for future collaborations. The participants included 22 researchers from Japan and the United States as well as seven researchers from Europe and Russia. There have been important changes in the programs in both the US and Japan in the areas of plasma surface interactions and plasma facing components. The US has moved away from a strong focus on the ITER Project and has introduced new programs on use of liquid surfaces for plasma facing components, and operation of NSTX has begun. In Japan, the Large Helical Device began operation. This is the first large world-class confinement device operating in a magnetic configuration different than a tokamak. In selecting the presentations for this workshop, the organizers sought a balance between research in laboratory facilities or confinement devices related to plasma surface interactions and experimental research in the development of plasma facing components. In discussions about the workshop itself, the participants affirmed their preference for a setting where ''work-in-progress'' could be informally presented and discussed.

  15. Comparison and evaluation between 3D-bolus and step-bolus, the assistive radiotherapy devices for the patients who had undergone modified radical mastectomy surgery

    Energy Technology Data Exchange (ETDEWEB)

    Jang, Won Seok; Park, Kwang Woo; Shin, Dong Bong; Kim, Jong Dae; Kim, Sei Joon; Ha, Jin Sook; Jeon, Mi Jin; Cho, Yoojin; Jung, Inho [Dept. of Radiation Oncology, Gangnam Severance Hospital, Seoul, (Korea, Republic of)

    2016-06-15

    This study aimed to compare and evaluate between the efficiency of two respective devices, 3D-bolus and step-bolus when the devices were used for the treatment of patients whose chest walls were required to undergo the electron beam therapy after the surgical procedure of modified radical mastectomy, MRM. The treatment plan of reverse hockey stick method, using the photon beam and electron beam, had been set for six breast cancer patients and these 6 breast cancer patients were selected to be the subjects for this study. The prescribed dose of electron beam for anterior chest wall was set to be 180 cGy per treatment and both the 3D-bolus, produced using 3D printer(CubeX, 3D systems, USA) and the self-made conventional step-bolus were used respectively. The surface dose under 3D-bolus and step-bolus was measured at 5 measurement spots of iso-center, lateral, medial, superior and inferior point, using GAFCHROMIC EBT3 film (International specialty products, USA) and the measured value of dose at 5 spots was compared and analyzed. Also the respective treatment plan was devised, considering the adoption of 3D-bolus and stepbolus and the separate treatment results were compared to each other. The average surface dose was 179.17 cGy when the device of 3D-bolus was adopted and 172.02 cGy when step-bolus was adopted. The average error rate against the prescribed dose of 180 cGy was -(minus) 0.47% when the device of 3D-bolus was adopted and it was -(minus) 4.43% when step-bolus was adopted. It was turned out that the maximum error rate at the point of iso-center was 2.69%, in case of 3D-bolus adoption and it was 5,54% in case of step-bolus adoption. The maximum discrepancy in terms of treatment accuracy was revealed to be about 6% when step-bolus was adopted and to be about 3% when 3D-bolus was adopted. The difference in average target dose on chest wall between 3D-bolus treatment plan and step-bolus treatment plan was shown to be insignificant as the difference was only 0

  16. Comparison and evaluation between 3D-bolus and step-bolus, the assistive radiotherapy devices for the patients who had undergone modified radical mastectomy surgery

    International Nuclear Information System (INIS)

    Jang, Won Seok; Park, Kwang Woo; Shin, Dong Bong; Kim, Jong Dae; Kim, Sei Joon; Ha, Jin Sook; Jeon, Mi Jin; Cho, Yoojin; Jung, Inho

    2016-01-01

    This study aimed to compare and evaluate between the efficiency of two respective devices, 3D-bolus and step-bolus when the devices were used for the treatment of patients whose chest walls were required to undergo the electron beam therapy after the surgical procedure of modified radical mastectomy, MRM. The treatment plan of reverse hockey stick method, using the photon beam and electron beam, had been set for six breast cancer patients and these 6 breast cancer patients were selected to be the subjects for this study. The prescribed dose of electron beam for anterior chest wall was set to be 180 cGy per treatment and both the 3D-bolus, produced using 3D printer(CubeX, 3D systems, USA) and the self-made conventional step-bolus were used respectively. The surface dose under 3D-bolus and step-bolus was measured at 5 measurement spots of iso-center, lateral, medial, superior and inferior point, using GAFCHROMIC EBT3 film (International specialty products, USA) and the measured value of dose at 5 spots was compared and analyzed. Also the respective treatment plan was devised, considering the adoption of 3D-bolus and stepbolus and the separate treatment results were compared to each other. The average surface dose was 179.17 cGy when the device of 3D-bolus was adopted and 172.02 cGy when step-bolus was adopted. The average error rate against the prescribed dose of 180 cGy was -(minus) 0.47% when the device of 3D-bolus was adopted and it was -(minus) 4.43% when step-bolus was adopted. It was turned out that the maximum error rate at the point of iso-center was 2.69%, in case of 3D-bolus adoption and it was 5,54% in case of step-bolus adoption. The maximum discrepancy in terms of treatment accuracy was revealed to be about 6% when step-bolus was adopted and to be about 3% when 3D-bolus was adopted. The difference in average target dose on chest wall between 3D-bolus treatment plan and step-bolus treatment plan was shown to be insignificant as the difference was only 0

  17. Multi-step resistive switching behavior of Li-doped ZnO resistance random access memory device controlled by compliance current

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Chun-Cheng [Department of Electrical Engineering, National Cheng Kung University, Tainan 701, Taiwan (China); Department of Mathematic and Physical Sciences, R.O.C. Air Force Academy, Kaohsiung 820, Taiwan (China); Tang, Jian-Fu; Su, Hsiu-Hsien [Department of Electrical Engineering, National Cheng Kung University, Tainan 701, Taiwan (China); Hong, Cheng-Shong; Huang, Chih-Yu [Department of Electronic Engineering, National Kaohsiung Normal University, Kaohsiung 802, Taiwan (China); Chu, Sheng-Yuan, E-mail: chusy@mail.ncku.edu.tw [Department of Electrical Engineering, National Cheng Kung University, Tainan 701, Taiwan (China); Center for Micro/Nano Science and Technology, National Cheng Kung University, Tainan 701, Taiwan (China)

    2016-06-28

    The multi-step resistive switching (RS) behavior of a unipolar Pt/Li{sub 0.06}Zn{sub 0.94}O/Pt resistive random access memory (RRAM) device is investigated. It is found that the RRAM device exhibits normal, 2-, 3-, and 4-step RESET behaviors under different compliance currents. The transport mechanism within the device is investigated by means of current-voltage curves, in-situ transmission electron microscopy, and electrochemical impedance spectroscopy. It is shown that the ion transport mechanism is dominated by Ohmic behavior under low electric fields and the Poole-Frenkel emission effect (normal RS behavior) or Li{sup +} ion diffusion (2-, 3-, and 4-step RESET behaviors) under high electric fields.

  18. HIA, the next step: Defining models and roles

    International Nuclear Information System (INIS)

    Putters, Kim

    2005-01-01

    If HIA is to be an effective instrument for optimising health interests in the policy making process it has to recognise the different contests in which policy is made and the relevance of both technical rationality and political rationality. Policy making may adopt a rational perspective in which there is a systematic and orderly progression from problem formulation to solution or a network perspective in which there are multiple interdependencies, extensive negotiation and compromise, and the steps from problem to formulation are not followed sequentially or in any particular order. Policy problems may be simple with clear causal pathways and responsibilities or complex with unclear causal pathways and disputed responsibilities. Network analysis is required to show which stakeholders are involved, their support for health issues and the degree of consensus. From this analysis three models of HIA emerge. The first is the phases model which is fitted to simple problems and a rational perspective of policymaking. This model involves following structured steps. The second model is the rounds (Echternach) model that is fitted to complex problems and a network perspective of policymaking. This model is dynamic and concentrates on network solutions taking these steps in no particular order. The final model is the 'garbage can' model fitted to contexts which combine simple and complex problems. In this model HIA functions as a problem solver and signpost keeping all possible solutions and stakeholders in play and allowing solutions to emerge over time. HIA models should be the beginning rather than the conclusion of discussion the worlds of HIA and policymaking

  19. Proceedings of US/Japan workshop, Q219 on high heat flux components and plasma surface interactions for next fusion devices

    Energy Technology Data Exchange (ETDEWEB)

    Ulrickson, M.A.; Stevens, P.L.; Hino, T.; Hirohata, Y. [eds.

    1996-12-01

    This report contains the viewgraphs from the proceedings of US/Japan Workshop on High Heat Flux Components and Plasma Surface Interactions for Next Fusion Devices. Some of the general topics covered by this report are: PFC/PSI in tokamak and helical devices; development of high heat flux components; PSIS and plasma facing materials;tritium; and material damage.

  20. Proceedings of US/Japan workshop, Q219 on high heat flux components and plasma surface interactions for next fusion devices

    International Nuclear Information System (INIS)

    Ulrickson, M.A.; Stevens, P.L.; Hino, T.; Hirohata, Y.

    1996-12-01

    This report contains the viewgraphs from the proceedings of US/Japan Workshop on High Heat Flux Components and Plasma Surface Interactions for Next Fusion Devices. Some of the general topics covered by this report are: PFC/PSI in tokamak and helical devices; development of high heat flux components; PSIS and plasma facing materials;tritium; and material damage

  1. Taking the Plunge: Next Steps in Engaged Learning: Project Kaleidoscope-Connecticut Conference of Independent Colleges Conference for Science Educators.

    Science.gov (United States)

    Frederick, Jennifer

    2010-09-01

    College and university science educators from across Connecticut gathered at Yale's West Campus in April 2010 for a Project Kaleidoscope (PKAL) program entitled "Taking the Plunge: Next Steps in Engaged Learning." Funded by the National Science Foundation (NSF) and co-sponsored by the Connecticut Conference of Independent Colleges (CCIC) and Yale's McDougal Graduate Teaching Center, the event was the latest in a PKAL series of one-day conferences aimed at equipping science, technology, engineering, and math (STEM) instructors with effective approaches to engaging students and training future scientists.

  2. Single cells as experimentation units in lab-on-a-chip devices

    NARCIS (Netherlands)

    le Gac, Severine; van den Berg, Albert

    'Lab-on-a-chip' technology (LOC) has now reached a mature state and is employed commonly in research in the life sciences. LOC devices make novel experimentation possible while providing a sophisticated environment for cellular investigation. As a next step, we introduce here the concept of a

  3. First steps towards the realization of a double layer perceptron based on organic memristive devices

    Science.gov (United States)

    Emelyanov, A. V.; Lapkin, D. A.; Demin, V. A.; Erokhin, V. V.; Battistoni, S.; Baldi, G.; Dimonte, A.; Korovin, A. N.; Iannotta, S.; Kashkarov, P. K.; Kovalchuk, M. V.

    2016-11-01

    Memristors are widely considered as promising elements for the efficient implementation of synaptic weights in artificial neural networks (ANNs) since they are resistors that keep memory of their previous conductive state. Whereas demonstrations of simple neural networks (e.g., a single-layer perceptron) based on memristors already exist, the implementation of more complicated networks is more challenging and has yet to be reported. In this study, we demonstrate linearly nonseparable combinational logic classification (XOR logic task) using a network implemented with CMOS-based neurons and organic memrisitive devices that constitutes the first step toward the realization of a double layer perceptron. We also show numerically the ability of such network to solve a principally analogue task which cannot be realized by digital devices. The obtained results prove the possibility to create a multilayer ANN based on memristive devices that paves the way for designing a more complex network such as the double layer perceptron.

  4. First steps towards the realization of a double layer perceptron based on organic memristive devices

    Directory of Open Access Journals (Sweden)

    A. V. Emelyanov

    2016-11-01

    Full Text Available Memristors are widely considered as promising elements for the efficient implementation of synaptic weights in artificial neural networks (ANNs since they are resistors that keep memory of their previous conductive state. Whereas demonstrations of simple neural networks (e.g., a single-layer perceptron based on memristors already exist, the implementation of more complicated networks is more challenging and has yet to be reported. In this study, we demonstrate linearly nonseparable combinational logic classification (XOR logic task using a network implemented with CMOS-based neurons and organic memrisitive devices that constitutes the first step toward the realization of a double layer perceptron. We also show numerically the ability of such network to solve a principally analogue task which cannot be realized by digital devices. The obtained results prove the possibility to create a multilayer ANN based on memristive devices that paves the way for designing a more complex network such as the double layer perceptron.

  5. Change in energy market in order to make the next cultural step; Umbruch im Energiemarkt als das Erklimmen einer neuen Kulturstufe

    Energy Technology Data Exchange (ETDEWEB)

    Hein, Franz [mpc management project coaching, Esslingen (Germany)

    2011-07-01

    The upcoming radical change in energy market will be more than complete shift to renewables. It will change the usage of energy. Up to now we lived in an ''energy paradise''. Without a thought about the needs of the next generations we reduced the storages of fossil fuels. In the future we will use only energy offered by the sun - directly or indirectly (e.g. wind energy) - or energy we stored before. We will have to make the next cultural step. We have to cope the extremely volatility of energy production. It is similar to the times, when we made the change from hunters and gatherers to tillers and stockbreeders: They had to learn how to manage the volatile offering of water and to store harvest. (orig.)

  6. Sealed Orifice Laparoscopic or Endoscopic (SOLE) Surgery: technology and technique convergence for next-step colorectal surgery.

    LENUS (Irish Health Repository)

    Cahill, R A

    2012-02-01

    The new avenue of minimally invasive surgery, referred to as single-incision\\/access laparoscopy, is often presented as an alternative to standard multiport approaches, whereas in fact it is more usefully perceived as a complementary modality. The emergence of the technique can be of greater use both to patients and to the colorectal specialty if its principles can be merged into next-stage evolution by synergy with more conventional practice. In particular, rather than device specificity, what is needed is convergence of capability that can be applied by the same surgeon in differing scenarios depending on the individualized patient and disease characteristics. We detail here the global applicability of a simple access device construct that allows the provision of simple and complex single-port laparoscopy as well as contributing to multiport laparoscopic and transanal resections in a manner that is reliable, reproducible, ergonomical and economical.

  7. Modified precision lingual bonding technique: A step-wise approach with torque angulation device-bracket positioning device

    Directory of Open Access Journals (Sweden)

    Rosaline Tina Paul

    2017-01-01

    Full Text Available Objectives: Contemporary preadjusted edgewise appliance is all about the precision in bracket design, prescription and positioning in addition to the orthodontist's skill and training. However, achieving it is a bigger challenge as the anatomy of the lingual surface of a tooth is uneven, dissimilar, and moreover the tooth alignment on the lingual surface is variant. Thus, the need for an accurate method of bracket positioning with predetermined torque and angulation incorporated in the brackets according to the patients' need is of key importance. Materials and Methods: A TAD-BPD machine used to enhance the accuracy of bracket positioning and bioplast accurate tray transfer technique was used. Results: A step-wise procedures in bracket positioning and fabricating an indirect bonding tray for lingual orthodontics using the torque angulation device-bracket positioning device. Conclusions: This technique facilitated unhindered bonding even in severely crowded cases and easy rebonding during mid-treatment stages.

  8. Safety analysis and evaluation of the next fusion device

    International Nuclear Information System (INIS)

    Kobayashi, Shigetada; Honda, Tsutomu; Ohmura, Hiroshi; Kawai, Masayoshi; Shimizu, Takeshi; Yamaoka, Mitsuaki; Nakahara, Katsuhiko; Seki, Yasushi.

    1988-12-01

    As a part of safety evaluation, a probabilistic risk assessment (PRA) has been attempted for the Next Fusion Device system. Among the various events related to safety, a number of representative events have been selected for assessment, from the events in normal operation state, repair and maintenance state and accidental state. In the first chapter, in order to conduct the probabilistic risk assessment of the whole Fusion Experimental Reactor (FER), the data base required for the analysis was investigated in 1.1, the results on the failure mode and effects analysis (FMEA), accident sequence, radioactive inventory leakage flow path, event tree analysis (ETA) and fault tree analysis (FTA) were summarized in 1.2 to 1.5, respectively. Based on these results, accident initiating events were evaluated in 1.6, and overall risk was assessed in 1.7 and the tasks for the future were summarized in 1.8. It is important to analyze and evaluate various events during normal operations, repair and maintenance and accidents. However, due to the large uncertainties in the modeling of phenomena or the data base, there are many events for which realistic analyses are difficult. Three such events were selected and studied in chapter two. In 2.1, the temperature rise in the reactor structure after the Loss-of-Coolant-Accident caused by the decay heat under various heat removal conditions were investigated. In 2.2, the radiation dose of personnel during repair and maintenance period caused by the release of activated dust were estimated. Lastly, in 2.3 tritium behavior in the stainless steel first wall and graphite armour were studied. (author)

  9. Humanitarian Use Device and Humanitarian Device Exemption regulatory programs: pros and cons.

    Science.gov (United States)

    Bernad, Daniel Maxwell

    2009-03-01

    The US FDA established the Humanitarian Use Device (HUD) and Humanitarian Device Exemption (HDE) program to encourage medical device firms to address rare diseases. Despite being in existence for over a decade, there has only been one peer-reviewed publication examining this field. The objective of this report is to investigate how the HUD/HDE program differs from the standard regulatory system, discuss its potential advantages and disadvantages, and to speculate which humanitarian devices will be brought to market within the next 5 years. A total of 40 semistructured interviews with stakeholders, representing approximately half (n = 20, 49%) of the firms that have successfully obtained HDE-approved products, were performed in order to acquire the primary data for this paper. There appear to be short-term gains and long-term drains associated with launching humanitarian devices to market. This report aims to provide sponsors with information that may allow them to make better decisions during their product development of humanitarian devices and may, hopefully, also play a role in encouraging other sponsors to take the necessary steps forward in helping to find treatments for patients with rare diseases.

  10. Latest developments in image processing for the next generation of devices with a view on DEMO

    International Nuclear Information System (INIS)

    Murari, A.; Vega, J.; Mazon, D.; Arena, P.; Craciunescu, T.; Gabellieri, L.; Gelfusa, M.; Pacella, D.; Palazzo, S.; Romano, A.

    2012-01-01

    Highlights: ► Pattern recognition methods have been successfully applied to retrieve frames in massime databases. ► The technology of Cellular Nonlinear Networks (CNNs) has been upgraded to solve space variant problem. ► The CNNs have then been successfully applied to various tasks, from the real time hot spot detection to the automatic identification of instabilities. ► The method of the optical flow permits to derive information about the speed of the objects moving in the frames of a single camera. ► Since the next generation of devices will emit a lot of SXR radiation, also from the edge, new technologies (Gas Electron Multiplier detectors and policapillary lenses) are being developed to perform imaging over this region of the spectrum for a global view of the entire plasma column. - Abstract: In magnetic confinement fusion devices the use of cameras, both visible and infrared, has increased very significantly in the last years. The large amount of data (in the range of tens of Gbytes per shot) and the difficulty of the analysis tasks (ambiguity, ill posed problems, etc.), require new solutions. The technology of Cellular Nonlinear Networks (CNNs) has been successfully applied to various tasks, from the real time hot spot detection to the automatic identification of instabilities. The accuracy obtained is comparable to the one of more traditional serial algorithms but the CCNs guarantee deterministic computational times independently from the image contents. Moreover the latest developments have allowed obtaining these results also in the case of space variant image analysis, without compromising the computational speed (of the order of ten thousand frames per second). The method of the optical flow permits to derive information about the speed of the objects moving in the frames of a single camera. The results of previous applications have been so successful that the approach has been extended to videos in compressed format (MPEG) to reduce the

  11. Step Detection Robust against the Dynamics of Smartphones

    Science.gov (United States)

    Lee, Hwan-hee; Choi, Suji; Lee, Myeong-jin

    2015-01-01

    A novel algorithm is proposed for robust step detection irrespective of step mode and device pose in smartphone usage environments. The dynamics of smartphones are decoupled into a peak-valley relationship with adaptive magnitude and temporal thresholds. For extracted peaks and valleys in the magnitude of acceleration, a step is defined as consisting of a peak and its adjacent valley. Adaptive magnitude thresholds consisting of step average and step deviation are applied to suppress pseudo peaks or valleys that mostly occur during the transition among step modes or device poses. Adaptive temporal thresholds are applied to time intervals between peaks or valleys to consider the time-varying pace of human walking or running for the correct selection of peaks or valleys. From the experimental results, it can be seen that the proposed step detection algorithm shows more than 98.6% average accuracy for any combination of step mode and device pose and outperforms state-of-the-art algorithms. PMID:26516857

  12. Next-generation phylogenomics

    Directory of Open Access Journals (Sweden)

    Chan Cheong Xin

    2013-01-01

    Full Text Available Abstract Thanks to advances in next-generation technologies, genome sequences are now being generated at breadth (e.g. across environments and depth (thousands of closely related strains, individuals or samples unimaginable only a few years ago. Phylogenomics – the study of evolutionary relationships based on comparative analysis of genome-scale data – has so far been developed as industrial-scale molecular phylogenetics, proceeding in the two classical steps: multiple alignment of homologous sequences, followed by inference of a tree (or multiple trees. However, the algorithms typically employed for these steps scale poorly with number of sequences, such that for an increasing number of problems, high-quality phylogenomic analysis is (or soon will be computationally infeasible. Moreover, next-generation data are often incomplete and error-prone, and analysis may be further complicated by genome rearrangement, gene fusion and deletion, lateral genetic transfer, and transcript variation. Here we argue that next-generation data require next-generation phylogenomics, including so-called alignment-free approaches. Reviewers Reviewed by Mr Alexander Panchin (nominated by Dr Mikhail Gelfand, Dr Eugene Koonin and Prof Peter Gogarten. For the full reviews, please go to the Reviewers’ comments section.

  13. Trainer variability during step training after spinal cord injury: Implications for robotic gait-training device design

    OpenAIRE

    Jose A. Galvez, PhD; Amy Budovitch, PT; Susan J. Harkema, PhD; David J. Reinkensmeyer, PhD

    2011-01-01

    Robotic devices are being developed to automate repetitive aspects of walking retraining after neurological injuries, in part because they might improve the consistency and quality of training. However, it is unclear how inconsistent manual training actually is or whether stepping quality depends strongly on the trainers' manual skill. The objective of this study was to quantify trainer variability of manual skill during step training using body-weight support on a treadmill and assess factor...

  14. Next steps towards a Climate Innovation Centre in Ghana. Discussion Paper

    International Nuclear Information System (INIS)

    De Coninck, H.C.; Wuertenberger, L.; Akon-Yamga, G.

    2011-03-01

    A climate innovation centre is an institution aimed at enabling development through catalysing climate technology research, development, market creation and policy. This discussion paper discusses the possibilities, considerations and next steps for a Climate Innovation Centre (CIC) in Ghana based on new insights within the government of Ghana, a mapping of climate innovation in Ghana, new developments in the international climate negotiations and other multilateral processes, and analysis conducted by ECN. The conclusion is that a Climate Innovation Centre can fill significant gaps in climate resilient development in Ghana. It seems important that a Ghana CIC does not become yet another institution that focuses on basic research in the area of climate change. Rather, it should connect the dots of the Ghanaian climate innovation system and act as a knowledge facilitator, also for the private sector. Various models of climate innovation centres exist. Before choices are made for a model or a combination of models for Ghana, it is recommended to allow for a broad stakeholder process. The World Bank's infoDev programme could be a model for such a process. Such stakeholder engagement should be aligned with other policymaking processes on adaptation and low-carbon development, as well as related policy arenas, such as agriculture, transport, waste and energy.

  15. Next steps towards a Climate Innovation Centre in Ghana. Discussion Paper

    Energy Technology Data Exchange (ETDEWEB)

    De Coninck, H.C.; Wuertenberger, L. [ECN Policy Studies, Petten (Netherlands); Akon-Yamga, G. [Science and Technology Policy Research Institute STEPRI, Accra (Guinea)

    2011-03-15

    A climate innovation centre is an institution aimed at enabling development through catalysing climate technology research, development, market creation and policy. This discussion paper discusses the possibilities, considerations and next steps for a Climate Innovation Centre (CIC) in Ghana based on new insights within the government of Ghana, a mapping of climate innovation in Ghana, new developments in the international climate negotiations and other multilateral processes, and analysis conducted by ECN. The conclusion is that a Climate Innovation Centre can fill significant gaps in climate resilient development in Ghana. It seems important that a Ghana CIC does not become yet another institution that focuses on basic research in the area of climate change. Rather, it should connect the dots of the Ghanaian climate innovation system and act as a knowledge facilitator, also for the private sector. Various models of climate innovation centres exist. Before choices are made for a model or a combination of models for Ghana, it is recommended to allow for a broad stakeholder process. The World Bank's infoDev programme could be a model for such a process. Such stakeholder engagement should be aligned with other policymaking processes on adaptation and low-carbon development, as well as related policy arenas, such as agriculture, transport, waste and energy.

  16. Security in the Cache and Forward Architecture for the Next Generation Internet

    Science.gov (United States)

    Hadjichristofi, G. C.; Hadjicostis, C. N.; Raychaudhuri, D.

    The future Internet architecture will be comprised predominately of wireless devices. It is evident at this stage that the TCP/IP protocol that was developed decades ago will not properly support the required network functionalities since contemporary communication profiles tend to be data-driven rather than host-based. To address this paradigm shift in data propagation, a next generation architecture has been proposed, the Cache and Forward (CNF) architecture. This research investigates security aspects of this new Internet architecture. More specifically, we discuss content privacy, secure routing, key management and trust management. We identify security weaknesses of this architecture that need to be addressed and we derive security requirements that should guide future research directions. Aspects of the research can be adopted as a step-stone as we build the future Internet.

  17. Self-shielding characteristics of aqueous self-cooled blankets for next generation fusion devices

    International Nuclear Information System (INIS)

    Pelloni, S.; Cheng, E.T.; Embrechts, M.J.

    1987-11-01

    The present study examines self-shielding characteristics for two aqueous self-cooled tritium producing driver blankets for next generation fusion devices. The aqueous Self-Cooled Blanket concept (ASCB) is a very simple blanket concept that relies on just structural material and coolant. Lithium compounds are dissolved in water to provide for tritium production. An ASCB driver blanket would provide a low technology and low temperature environment for blanket test modules in a next generation fusion reactor. The primary functions of such a blanket would be shielding, energy removal and tritium production. One driver blanket considered in this study concept relates to the one proposed for the Next European Torus (NET), while the second concept is indicative for the inboard shield design for the Engineering Test Reactor proposed by the USA (TIBER II/ETR). The driver blanket for NET is based on stainless steel for the structural material and aqueous solution, while the inboard shielding blanket for TIBER II/ETR is based on a tungsten/aqueous solution combination. The purpose of this study is to investigate self-shielding and heterogeneity effects in aqueous self-cooled blankets. It is found that no significant gains in tritium breeding can be achieved in the stainless steel blanket if spatial and energy self-shielding effects are considered, and the heterogeneity effects are also insignificant. The tungsten blanket shows a 5 percent increase in tritium production in the shielding blanket when energy and spatial self-shielding effects are accounted for. However, the tungsten blanket shows a drastic increase in the tritium breeding ratio due to heterogeneity effects. (author) 17 refs., 9 figs., 9 tabs

  18. Development of real time diagnostics and feedback algorithms for JET in view of the next step

    Energy Technology Data Exchange (ETDEWEB)

    Murari, A.; Barana, O. [Consorzio RFX Associazione EURATOM ENEA per la Fusione, Corso Stati Uniti 4, Padua (Italy); Felton, R.; Zabeo, L.; Piccolo, F.; Sartori, F. [Euratom/UKAEA Fusion Assoc., Culham Science Centre, Abingdon, Oxon (United Kingdom); Joffrin, E.; Mazon, D.; Laborde, L.; Moreau, D. [Association EURATOM-CEA, CEA Cadarache, 13 - Saint-Paul-lez-Durance (France); Albanese, R. [Assoc. Euratom-ENEA-CREATE, Univ. Mediterranea RC (Italy); Arena, P.; Bruno, M. [Assoc. Euratom-ENEA-CREATE, Univ.di Catania (Italy); Ambrosino, G.; Ariola, M. [Assoc. Euratom-ENEA-CREATE, Univ. Napoli Federico Napoli (Italy); Crisanti, F. [Associazone EURATOM ENEA sulla Fusione, C.R. Frascati (Italy); Luna, E. de la; Sanchez, J. [Associacion EURATOM CIEMAT para Fusion, Madrid (Spain)

    2004-07-01

    Real time control of many plasma parameters will be an essential aspect in the development of reliable high performance operation of Next Step Tokamaks. The main prerequisites for any feedback scheme are the precise real-time determination of the quantities to be controlled, requiring top quality and highly reliable diagnostics, and the availability of robust control algorithms. A new set of real time diagnostics was recently implemented on JET to prove the feasibility of determining, with high accuracy and time resolution, the most important plasma quantities. With regard to feedback algorithms, new model-based controllers were developed to allow a more robust control of several plasma parameters. Both diagnostics and algorithms were successfully used in several experiments, ranging from H-mode plasmas to configuration with ITBs (internal thermal barriers). Since elaboration of computationally heavy measurements is often required, significant attention was devoted to non-algorithmic methods like Digital or Cellular Neural/Nonlinear Networks. The real time hardware and software adopted architectures are also described with particular attention to their relevance to ITER. (authors)

  19. Development of real time diagnostics and feedback algorithms for JET in view of the next step

    International Nuclear Information System (INIS)

    Murari, A.; Felton, R.; Zabeo, L.; Piccolo, F.; Sartori, F.; Murari, A.; Barana, O.; Albanese, R.; Joffrin, E.; Mazon, D.; Laborde, L.; Moreau, D.; Arena, P.; Bruno, M.; Ambrosino, G.; Ariola, M.; Crisanti, F.; Luna, E. de la; Sanchez, J.

    2004-01-01

    Real time control of many plasma parameters will be an essential aspect in the development of reliable high performance operation of Next Step Tokamaks. The main prerequisites for any feedback scheme are the precise real-time determination of the quantities to be controlled, requiring top quality and highly reliable diagnostics, and the availability of robust control algorithms. A new set of real time diagnostics was recently implemented on JET to prove the feasibility of determining, with high accuracy and time resolution, the most important plasma quantities. With regard to feedback algorithms, new model-based controllers were developed to allow a more robust control of several plasma parameters. Both diagnostics and algorithms were successfully used in several experiments, ranging from H-mode plasmas to configuration with internal transport barriers. Since elaboration of computationally heavy measurements is often required, significant attention was devoted to non-algorithmic methods like Digital or Cellular Neural/Nonlinear Networks. The real time hardware and software adopted architectures are also described with particular attention to their relevance to ITER. (authors)

  20. Development of real time diagnostics and feedback algorithms for JET in view of the next step

    International Nuclear Information System (INIS)

    Murari, A.; Barana, O.; Murari, A.; Felton, R.; Zabeo, L.; Piccolo, F.; Sartori, F.; Joffrin, E.; Mazon, D.; Laborde, L.; Moreau, D.; Albanese, R.; Arena, P.; Bruno, M.; Ambrosino, G.; Ariola, M.; Crisanti, F.; Luna, E. de la; Sanchez, J.

    2004-01-01

    Real time control of many plasma parameters will be an essential aspect in the development of reliable high performance operation of Next Step Tokamaks. The main prerequisites for any feedback scheme are the precise real-time determination of the quantities to be controlled, requiring top quality and highly reliable diagnostics, and the availability of robust control algorithms. A new set of real time diagnostics was recently implemented on JET to prove the feasibility of determining, with high accuracy and time resolution, the most important plasma quantities. With regard to feedback algorithms, new model-based controllers were developed to allow a more robust control of several plasma parameters. Both diagnostics and algorithms were successfully used in several experiments, ranging from H-mode plasmas to configuration with ITBs (internal thermal barriers). Since elaboration of computationally heavy measurements is often required, significant attention was devoted to non-algorithmic methods like Digital or Cellular Neural/Nonlinear Networks. The real time hardware and software adopted architectures are also described with particular attention to their relevance to ITER. (authors)

  1. Advanced, High Power, Next Scale, Wave Energy Conversion Device

    Energy Technology Data Exchange (ETDEWEB)

    Mekhiche, Mike [Principal Investigator; Dufera, Hiz [Project Manager; Montagna, Deb [Business Point of Contact

    2012-10-29

    The project conducted under DOE contract DE‐EE0002649 is defined as the Advanced, High Power, Next Scale, Wave Energy Converter. The overall project is split into a seven‐stage, gated development program. The work conducted under the DOE contract is OPT Stage Gate III work and a portion of Stage Gate IV work of the seven stage product development process. The project effort includes Full Concept Design & Prototype Assembly Testing building on our existing PowerBuoy technology to deliver a device with much increased power delivery. Scaling‐up from 150kW to 500kW power generating capacity required changes in the PowerBuoy design that addressed cost reduction and mass manufacturing by implementing a Design for Manufacturing (DFM) approach. The design changes also focused on reducing PowerBuoy Installation, Operation and Maintenance (IO&M) costs which are essential to reducing the overall cost of energy. In this design, changes to the core PowerBuoy technology were implemented to increase capability and reduce both CAPEX and OPEX costs. OPT conceptually envisaged moving from a floating structure to a seabed structure. The design change from a floating structure to seabed structure would provide the implementation of stroke‐ unlimited Power Take‐Off (PTO) which has a potential to provide significant power delivery improvement and transform the wave energy industry if proven feasible.

  2. The scientific prototype, the only reasonable next step for the American MFE program; or why FESAC will never solicit my advice again

    Science.gov (United States)

    Manheimer, Wallace

    2014-10-01

    The scientific prototype is a tokamak which builds on what has been accomplished in TFTR, JET and JT-60. Instead of attempting to advance the plasma parameters, or investigate a new confinement configuration, it takes the tokamak plasma parameters already achieved (or actually nearly already achieved), Q about 1 and run it at steady state or high duty cycle in a DT plasma. It is very much a nuclear device requiring all of the safeguards of any nuclear device. It is an important step forward for either pure fusion or fusion breeding, and it is difficult to see how fusion can advance very far with out the knowledge the scientific prototype would provide. The poster will be divided into two parts. The first part examines options other than the scientific prototype and shows why they should be rejected. The second part explains the scientific prototype in somewhat more detail.

  3. What's happening in 'renewable energy developed country: Germany'. Next step our country should learn

    International Nuclear Information System (INIS)

    Kitamura, Kazuya

    2012-01-01

    What's the next step our country should take? Japan could learn a lot of things such as success or failure examples from renewable energy developed country: Germany. This article reviewed present state of Feed-In Tariffs and renewable energy power in Germany. Share of renewable energy power amounted to 20% including 7.6% of wind power and 6.1% of biomass in 2011. Such trend caused increase of power cost, restructure of power system such as new installation of power transmission against north coast offshore wind power plant, and development of power storage system such as hydrogen production or pumped storage power plant. Efficient introduction of renewable energy should be planned in Japan based on appropriate share target of renewable energy share. As for nuclear power phaseout, Japan should learn German's experiences on decommissioning and decontamination of nuclear power plants, and policies of intermediate storage and final disposal of high-level radioactive wastes, which needed a long time and a great cost. (T. Tanaka)

  4. Major achievements of the European shield blanket R and D during the ITER EDA, and their relevance for future next step machines

    Energy Technology Data Exchange (ETDEWEB)

    Daenner, W. E-mail: daenner@ipp.mpg.de; Cardella, A.; Jones, L.; Lorenzetto, P.; Maisonnier, D.; Malavasi, G.; Peacock, A.; Rodgers, E.; Tavassoli, F

    2000-11-01

    In the frame of the international thermonuclear experimental reactors (ITER) collaboration, the European home team (EU HT) has committed significant efforts on the R and D for the Shield Blanket. This paper summarises the main achievements of this programme, which have been obtained over the last 7 years. The depth of R and D extends from generic activities up to the manufacture of prototypes, but has, in accordance with the design progress, reached different stages of maturity for the various components. New ITER options being considered since early 1998 have not made these activities irrelevant. With few exceptions, the results are still applicable for less ambitious next step machines, or transferable to components with similar functions or requirements.

  5. Next steps in the development of ecological soil clean-up values for metals.

    Science.gov (United States)

    Wentsel, Randall; Fairbrother, Anne

    2014-07-01

    This special series in Integrated Environmental Assessment Management presents the results from 6 workgroups that were formed at the workshop on Ecological Soil Levels-Next Steps in the Development of Metal Clean-Up Values (17-21 September 2012, Sundance, Utah). This introductory article presents an overview of the issues assessors face when conducting risk assessments for metals in soils, key US Environmental Protection Agency (USEPA) documents on metals risk assessment, and discusses the importance of leveraging from recent major terrestrial research projects, primarily to address Registration, Evaluation, Authorization and Restriction of Chemical Substances (REACH) requirements in Europe, that have significantly advanced our understanding of the behavior and toxicity of metals in soils. These projects developed large data sets that are useful for the risk assessment of metals in soil environments. The workshop attendees met to work toward developing a process for establishing ecological soil clean-up values (Eco-SCVs). The goal of the workshop was to progress from ecological soil screening values (Eco-SSLs) to final clean-up values by providing regulators with the methods and processes to incorporate bioavailability, normalize toxicity thresholds, address food-web issues, and incorporate background concentrations. The REACH data sets were used by workshop participants as case studies in the development of the ecological standards for soils. The workshop attendees discussed scientific advancements in bioavailability, soil biota and wildlife case studies, soil processes, and food-chain modeling. In addition, one of the workgroups discussed the processes needed to frame the topics to gain regulatory acceptance as a directive or guidance by Canada, the USEPA, or the United States. © 2013 SETAC.

  6. Design of next step tokamak: Consistent analysis of plasma performance flux composition and poloidal field system

    International Nuclear Information System (INIS)

    Ane, J.M.; Grandgirard, V.; Albajar, F.; Johner, J.

    2001-01-01

    A consistent and simple approach to derive plasma scenarios for next step tokamak design is presented. It is based on successive plasma equilibria snapshots from plasma breakdown to end of ramp-down. Temperature and density profiles for each equilibrium are derived from a 2D plasma model. The time interval between two successive equilibria is then computed from the toroidal field magnetic energy balance, the resistive term of which depends on n, T profiles. This approach provides a consistent analysis of plasma performance, flux consumption and PF system, including average voltages waveforms across the PF coils. The plasma model and the Poynting theorem for the toroidal magnetic energy are presented. Application to ITER-FEAT and to M2, a Q=5 machine designed at CEA, are shown. (author)

  7. Optical and electrical characterizations of a single step ion beam milling mesa devices of chloride passivated PbS colloidal quantum dots based film

    International Nuclear Information System (INIS)

    Hechster, Elad; Sarusi, Gabby; Shapiro, Arthur; Lifshitz, Efrat

    2016-01-01

    Colloidal Quantum Dots (CQDs) are of increasing interest, thanks to their quantum size effect that gives rise to their usage in various applications, such as biological tagging, solar cells and as the sensitizing layer of night vision devices. Here, we analyze the optical absorbance of chloride passivated PbS CQDs as well as revealing a correlation between their photoluminescence and sizes distribution, using theoretical models and experimental results from the literature. Next, we calculate the CQDs resistivity as a film. Although resistivity can be calculated from sheet resistance measurement using four point probes, such measurement is usually carried-out on the layer’s surface that in most cases has dangling bonds and surface states, which might affect the charges flow and modify the resistivity. Therefore; our approach, which was applied in this work, is to extract the actual resistivity from measurements that are performed along the film’s thickness (z-direction). For this intent, we fabricated gold capped PbS mesas devices using a single step Ion Beam Milling (IBM) process where we milled the gold and the PbS film continually, and then measured the vertical resistance. Knowing the mesas’ dimensions, we calculate the resistivity. To the best of our knowledge, no previous work has extracted, vertically, the resistivity of chloride passivated PbS CQDs using the above method.

  8. Optical and electrical characterizations of a single step ion beam milling mesa devices of chloride passivated PbS colloidal quantum dots based film

    Energy Technology Data Exchange (ETDEWEB)

    Hechster, Elad, E-mail: elad.hechster@gmail.com; Sarusi, Gabby [Electro-Optics Engineering Unit and Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, Beer-Sheva, 84100 Israel (Israel); Shapiro, Arthur; Lifshitz, Efrat [Schulich Faculty of Chemistry, Solid State Institute, Russel Berrie Nanotechnology Institute, Technion – Israel Institute of technology, 32000 Haifa (Israel)

    2016-07-15

    Colloidal Quantum Dots (CQDs) are of increasing interest, thanks to their quantum size effect that gives rise to their usage in various applications, such as biological tagging, solar cells and as the sensitizing layer of night vision devices. Here, we analyze the optical absorbance of chloride passivated PbS CQDs as well as revealing a correlation between their photoluminescence and sizes distribution, using theoretical models and experimental results from the literature. Next, we calculate the CQDs resistivity as a film. Although resistivity can be calculated from sheet resistance measurement using four point probes, such measurement is usually carried-out on the layer’s surface that in most cases has dangling bonds and surface states, which might affect the charges flow and modify the resistivity. Therefore; our approach, which was applied in this work, is to extract the actual resistivity from measurements that are performed along the film’s thickness (z-direction). For this intent, we fabricated gold capped PbS mesas devices using a single step Ion Beam Milling (IBM) process where we milled the gold and the PbS film continually, and then measured the vertical resistance. Knowing the mesas’ dimensions, we calculate the resistivity. To the best of our knowledge, no previous work has extracted, vertically, the resistivity of chloride passivated PbS CQDs using the above method.

  9. The next step: intelligent digital assistance for clinical operating rooms

    Directory of Open Access Journals (Sweden)

    Miehle Juliana

    2017-08-01

    Full Text Available With the emergence of new technologies, the surgical working environment becomes increasingly complex and comprises many medical devices that have to be taken cared of. However, the goal is to reduce the workload of the surgical team to allow them to fully focus on the actual surgical procedure. Therefore, new strategies are needed to keep the working environment manageable. Existing research projects in the field of intelligent medical environments mostly concentrate on workflow modeling or single smart features rather than building up a complete intelligent environment. In this article, we present the concept of intelligent digital assistance for clinical operating rooms (IDACO, providing the surgeon assistance in many different situations before and during an ongoing procedure using natural spoken language. The speech interface enables the surgeon to concentrate on the surgery and control the technical environment at the same time, without taking care of how to interact with the system. Furthermore, the system observes the context of the surgery and controls several devices autonomously at the appropriate time during the procedure.

  10. Creating the next steps to care: Maternal heath, improvisation, and Fulani women in Niamey, Niger.

    Science.gov (United States)

    Burgess, Sarah

    2016-12-01

    On paper, Niger's maternal healthcare system is extensively outlined by policies which assure access to certain services and create hierarchical referral chains. In practice it remains intensely improvisational: actors in the system must frequently make up the next steps to giving and receiving care, often outside the existing policies and procedures. Although population health in Niger has improved since the recently enacted gratuité des soins policy (which guarantees free access to certain material and child health services), care on the ground is still dictated by difficult circumstances and scarce resources. Health workers often lack the required medications and supplies; nevertheless, they must find ways to deliver services. Patients seeking maternal health services are frequently dissatisfied with the care they receive and so move forward of their own volition, by negotiating with health workers or by looking for services elsewhere. This research builds on recent scholarly work on improvisation, and asks us to further look at the ways that improvisation can be informed by the identity of the actors. Examining case studies of women from the Fulani ethnic group illustrates how particular cultural differences can inform improvisation. Analysing improvisation can also have policy implications; identifying typical points of departure from the official maternal health care system can reveal points where Niger can bolster its commitment to a universally high quality of care.

  11. A truly international lunar base as the next logical step for human spaceflight

    Science.gov (United States)

    Bonneville, R.

    2018-06-01

    A human mission to Mars has been highlighted as the long term goal for space exploration, with intermediate stages such as missions to the Moon and/or to asteroids, but a human mission to Mars will not be feasible before several decades. For the time being the major ambitious accomplishment in the field of human spaceflight is the International Space Station but a human spaceflight programme which would be restricted to Low Earth orbit (LEO) has indeed little interest. Thus the next step in the field of human exploration should be the definition of a new exploration programme beyond LEO, built within a long term perspective. We must acknowledge that science is not the main driver of human space exploration and that the main success of the ISS is to have allowed its partners to work together. The main goal of a new human exploration programme will be to promote international cooperation between the major space-faring countries. The only sensible and feasible objective of a near/mid-term human spaceflight programme should be the edification of a lunar base, under the condition that this base is built as a truly international venture. The ISS in the 1990s had illustrated a calmed relation between the USA, together with Europe, Canada and Japan, and Russia; a lunar base would be the symbol of a similar calmed relation between the same partners and China, and possibly others such as India. For the benefit of all humankind this extra continent, the Moon, should be used only for peaceful purposes like Antarctica today, and should not become the theatre or the stake of conflicts. Such a programme is technically feasible and financially affordable in a rather short term. So let us go to the Moon, but let us get there together.

  12. Description of the effort sharing approaches as presented in the Ecofys' policy brief The next step in Europe's climate action. Setting targets for 2030

    Energy Technology Data Exchange (ETDEWEB)

    Hoehne, N.; Hagemann, M.; Fekete, H. [Ecofys, Utrecht (Netherlands)

    2013-06-15

    The paper 'The next step in Europe's climate action. Setting targets for 2030' explains how setting 2030 targets will reinvigorate the ETS and will put EU emissions on track to limit global temperature increase below two degrees Celsius (2C). The paper describes four key findings for EU policymakers engaged in preparing EU energy and climate measures for 2030 and for the longer term. This document aims to provide background information on the effort sharing approaches, as presented in fore-mentioned paper.

  13. Next Gen One Portal Usability Evaluation

    Science.gov (United States)

    Cross, E. V., III; Perera, J. S.; Hanson, A. M.; English, K.; Vu, L.; Amonette, W.

    2018-01-01

    Each exercise device on the International Space Station (ISS) has a unique, customized software system interface with unique layouts / hierarchy, and operational principles that require significant crew training. Furthermore, the software programs are not adaptable and provide no real-time feedback or motivation to enhance the exercise experience and/or prevent injuries. Additionally, the graphical user interfaces (GUI) of these systems present information through multiple layers resulting in difficulty navigating to the desired screens and functions. These limitations of current exercise device GUI's lead to increased crew time spent on initiating, loading, performing exercises, logging data and exiting the system. To address these limitations a Next Generation One Portal (NextGen One Portal) Crew Countermeasure System (CMS) was developed, which utilizes the latest industry guidelines in GUI designs to provide an intuitive ease of use approach (i.e., 80% of the functionality gained within 5-10 minutes of initial use without/limited formal training required). This is accomplished by providing a consistent interface using common software to reduce crew training, increase efficiency & user satisfaction while also reducing development & maintenance costs. Results from the usability evaluations showed the NextGen One Portal UI having greater efficiency, learnability, memorability, usability and overall user experience than the current Advanced Resistive Exercise Device (ARED) UI used by astronauts on ISS. Specifically, the design of the One-Portal UI as an app interface similar to those found on the Apple and Google's App Store, assisted many of the participants in grasping the concepts of the interface with minimum training. Although the NextGen One-Portal UI was shown to be an overall better interface, observations by the test facilitators noted specific exercise tasks appeared to have a significant impact on the NextGen One-Portal UI efficiency. Future updates to

  14. Neutronic calculation of the next fuel elements for the Argonaut reactor

    International Nuclear Information System (INIS)

    Oliveira, C.R.E.; Brito Aghina, L.O. de

    1981-01-01

    The best parameters of the next fuel elements of the Argonaut reactor, at IEN (Instituto de Engenharia Nuclear - Brazil), were determined. The next fuel elements will be rods of an uranium mixture (19.98% enriched), graphite and bakelite. The parameters to be determined are: mixture density, percentage of uranium in the mixture, pellet radius, rod material and elements arrangement (step). The calculations routines consisted in the analysis of several steps, using the LEOPARD computer code for cell calculations and RMAT1D for one dimensional spatial calculations (criticality) with four energy groups. Finally a neutronic study of the Argounat reactors present configuration was done, using the HAMMER computer code (cell), the EXTERMINATOR computer code (two-dimensional calculations) and RAMAT1D. (Author) [pt

  15. Digital project management the complete step-by-step guide to a successful launch

    CERN Document Server

    Olson, Taylor

    2016-01-01

    The digital world is growing and changing at a rate that can seem overwhelming to those project managers who have to keep up with it to build customer-facing solutions and applications. It's rare for project managers working in this field to be provided with much direction or a process by which to carry out a project, and there has been next to nothing available specific to these types of projects in the literary marketplace. Digital Project Management: The Complete Step-by-Step Guide to a Successful Launch was developed to fill this gap by providing the knowledge, best practices and proven steps to consistently managing these types of project successfully from end-to-end now, and in the future with just minor adjustments to adapt to changes in technology.

  16. Left atrial appendage occlusion with the AMPLATZER Amulet device

    DEFF Research Database (Denmark)

    Tzikas, Apostolos; Gafoor, Sameer; Meerkin, David

    2016-01-01

    is proposed. Device preparation and de-airing is briefly described, followed by sheath exchange, device deployment steps, evaluation of device stability and decision for final release. The way to recapture and change a device is then shown, together with some additional tips on how to deal with challenging...... and had personal clinical experience with the AMPLATZER Amulet device were asked to contribute in the preparation of this consensus document. Twenty-seven physicians (20 interventional cardiologists and 7 electrophysiologists) from 14 different countries reviewed the manuscript. A step-by-step approach...

  17. Step-Up DC-DC converters

    DEFF Research Database (Denmark)

    Forouzesh, Mojtaba; Siwakoti, Yam P.; Gorji, Saman A.

    2017-01-01

    on the general law and framework of the development of next-generation step-up dc-dc converters, this paper aims to comprehensively review and classify various step-up dc-dc converters based on their characteristics and voltage-boosting techniques. In addition, the advantages and disadvantages of these voltage...

  18. Physical Configuration of the Next Generation Home Network

    Science.gov (United States)

    Terada, Shohei; Kakishima, Yu; Hanawa, Dai; Oguchi, Kimio

    The number of broadband users is rapidly increasing worldwide. Japan already has over 10 million FTTH users. Another trend is the rapid digitalization of home electrical equipment e. g. digital cameras and hard disc recorders. These trends will encourage the emergence of the next generation home network. In this paper, we introduce the next generation home network image and describe the five domains into which home devices can be classified. We then clarify the optimum medium with which to configure the network given the requirements imposed by the home environment. Wiring cable lengths for three network topologies are calculated. The results gained from the next generation home network implemented on the first phase testbed are shown. Finally, our conclusions are given.

  19. Next step in the ongoing arms race between myxoma virus and wild rabbits in Australia is a novel disease phenotype

    Science.gov (United States)

    Kerr, Peter J.; Cattadori, Isabella M.; Liu, June; Sim, Derek G.; Dodds, Jeff W.; Brooks, Jason W.; Kennett, Mary J.; Holmes, Edward C.

    2017-01-01

    In host–pathogen arms races, increases in host resistance prompt counteradaptation by pathogens, but the nature of that counteradaptation is seldom directly observed outside of laboratory models. The best-documented field example is the coevolution of myxoma virus (MYXV) in European rabbits. To understand how MYXV in Australia has continued to evolve in wild rabbits under intense selection for genetic resistance to myxomatosis, we compared the phenotypes of the progenitor MYXV and viral isolates from the 1950s and the 1990s in laboratory rabbits with no resistance. Strikingly, and unlike their 1950s counterparts, most virus isolates from the 1990s induced a highly lethal immune collapse syndrome similar to septic shock. Thus, the next step in this canonical case of coevolution after a species jump has been further escalation by the virus in the face of widespread host resistance. PMID:28808019

  20. A new SOI high-voltage device with a step-thickness drift region and its analytical model for the electric field and breakdown voltage

    International Nuclear Information System (INIS)

    Luo Xiaorong; Zhang Wei; Zhang Bo; Li Zhaoji; Yang Shouguo; Zhan Zhan; Fu Daping

    2008-01-01

    A new SOI high-voltage device with a step-thickness drift region (ST SOI) and its analytical model for the two-dimension electric field distribution and the breakdown voltage are proposed. The electric field in the drift region is modulated and that of the buried layer is enhanced by the variable thickness SOI layer, thereby resulting in the enhancement of the breakdown voltage. Based on the Poisson equation, the expression for the two-dimension electric field distribution is presented taking the modulation effect into account, from which the RESURF (REduced SURface Field) condition and the approximate but explicit expression for the maximal breakdown voltage are derived. The analytical model can explain the effects of the device parameters, such as the step height and the step length of the SOI layer, the doping concentration and the buried oxide thickness, on the electric field distribution and the breakdown voltage. The validity of this model is demonstrated by a comparison with numerical simulations. Improvement on both the breakdown voltage and the on-resistance (R on ) for the ST SOI is obtained due to the variable thickness SOI layer

  1. Thin film complementary metal oxide semiconductor (CMOS) device using a single-step deposition of the channel layer

    KAUST Repository

    Nayak, Pradipta K.

    2014-04-14

    We report, for the first time, the use of a single step deposition of semiconductor channel layer to simultaneously achieve both n-and p-type transport in transparent oxide thin film transistors (TFTs). This effect is achieved by controlling the concentration of hydroxyl groups (OH-groups) in the underlying gate dielectrics. The semiconducting tin oxide layer was deposited at room temperature, and the maximum device fabrication temperature was 350C. Both n and p-type TFTs showed fairly comparable performance. A functional CMOS inverter was fabricated using this novel scheme, indicating the potential use of our approach for various practical applications.

  2. Plasma Vertical Control with Internal and External Coils in Nest Step Tokamaks

    Energy Technology Data Exchange (ETDEWEB)

    C.E. Kessel; P. Heitzenroeder; C. Jun

    2000-11-03

    Vertical stability and control are examined for a tokamak configuration intended to be a generic representation of next step devices. Vertical stability calculations show that a critical resistive wall location can be determined for realistic structures, and that the introduction of small amounts of low resistivity material to an all steel structure can significantly reduce the vertical instability growth rate. Vertical control simulations show that internal control coils require significantly less feedback power than external coils, and that low resistivity materials can allow very low feedback powers or coils to be located externally with reasonable feedback powers.

  3. Trends in Mobile Computing: State-of-the-Art and Next Steps

    CERN Document Server

    CERN. Geneva

    2006-01-01

    Computing is moving to the edge of the network. It is becoming increasingly personal and allowing people to enjoy and express themselves in unprecedented ways. The same development allows professionals and enterprises to increase quality and productivity through improved mobility. The seminar discusses the underlying technical and societal trends and the state-of-the-art of mobile computing. Examples of current developments include the transformation of mobile devices into servers, augmented reality in mobile devices and the opportunities offered by wireless sensor networks. The fusion of the physical and digital worlds enabled by mobile computing is driving industry and society to adopt new uses of digital technologies and causing the focus of development to shift from hardware products to new services. Bio:Since 2004 Prof. Jan Bosch is working as Vice President and Head of the Software and Application Technology Laboratory of Nokia Research Centre in Helsinki, Finland. The Software & Application Tec...

  4. CAWSES (Climate and Weather of the Sun-Earth System) Science: Progress thus far and the next steps

    Science.gov (United States)

    Pallamraju, D.; Kozyra, J.; Basu, S.

    Climate and Weather of the Sun Earth System CAWSES is the current program of Scientific Committee for Solar Terrestrial Physics SCOSTEP for 2004 - 2008 The main aim of CAWSES is to bring together scientists from various nations to address the coupled and global nature of the Sun-Earth System phenomena Towards that end CAWSES provides a platform for international cooperation in observations data analysis theory and modeling There has been active international participation thus far with endorsement of the national CAWSES programs in some countries and many scientists around the globe actively volunteering their time in this effort The CAWSES Science Steering Group has organized the CAWSES program into five Themes for better execution of its science Solar Influence on Climate Space Weather Science and Applications Atmospheric Coupling Processes Space Climatology and Capacity Building and Education CAWSES will cooperate with International programs that focus on the Sun-Earth system science and at the same time compliment the work of programs whose scope is beyond the realm of CAWSES This talk will briefly review the science goals of CAWSES provide salient results from different Themes with emphasis on those from the Space Weather Theme This talk will also indicate the next steps that are being planned in this program and solicit inputs from the community for the science efforts to be carried out in the future

  5. Development of an efficient DC-DC SEPIC converter using wide bandgap power devices for high step-up applications

    Science.gov (United States)

    Al-bayati, Ali M. S.; Alharbi, Salah S.; Alharbi, Saleh S.; Matin, Mohammad

    2017-08-01

    A highly efficient high step-up dc-dc converter is the major requirement in the integration of low voltage renewable energy sources, such as photovoltaic panel module and fuel cell stacks, with a load or utility. This paper presents the development of an efficient dc-dc single-ended primary-inductor converter (SEPIC) for high step-up applications. Three SEPIC converters are designed and studied using different combinations of power devices: a combination based on all Si power devices using a Si-MOSFET and a Si-diode and termed as Si/Si, a combination based on a hybrid of Si and SiC power devices using the Si-MOSFET and a SiC-Schottky diode and termed as Si/SiC, and a combination based on all SiC power devices using a SiC-MOSFET and the SiC-Schottky diode and termed as SiC/SiC. The switching behavior of the Si-MOSFET and SiC-MOSFET is characterized and analyzed within the different combinations at the converter level. The effect of the diode type on the converter's overall performance is also discussed. The switching energy losses, total power losses, and the overall performance effciency of the converters are measured and reported under different switching frequencies. Furthermore, the potential of the designed converters to operate efficiently at a wide range of input voltages and output powers is studied. The analysis and results show an outstanding performance efficiency of the designed SiC/SiC based converter under a wide range of operating conditions.

  6. An improved protocol and a new grinding device for extraction of genomic DNA from microorganisms by a two-step extraction procedure.

    Science.gov (United States)

    Zhang, S S; Chen, D; Lu, Q

    2012-05-21

    Current protocols to extract genomic DNA from microorganisms are still laborious, tedious and costly, especially for the species with thick cell walls. In order to improve the effectiveness of extracting DNA from microbial samples, a novel protocol, defined as two-step extraction method, along with an improved tissue-grinding device, was developed. The protocol included two steps, disruption of microbial cells or spores by grinding the sample together with silica sand in a new device and extraction of DNA with an effective buffer containing cell lysis chemicals. The device was prepared by using a commercial electric mini-grinder, adapted with a grinding stone, and a sample cup processed by lathing from a polytetrafluoroethylene rod. We tested the method with vegetative cells of four microbial species and two microbial spores that have thick cell walls and are therefore hard to process; these included Escherichia coli JM109, Bacillus subtilis WB600, Sacchromyces cerevisiae INVSc1, Trichoderma viride AS3.3711, and the spores of S. cerevisiae and T. viride, respectively, representing Gram-positive bacteria, Gram-negative bacteria, yeast, filamentous fungi. We found that this new method and device extracted usable quantities of genomic DNA from the samples. The DNA fragments that were extracted exceeded 23 kb. The target sequences up to about 5 kb were successfully and exclusively amplified by PCR using extracted DNA as the template. In addition, the DNA extraction was finalized within 1.5 h. Thus, we conclude that this two-step extraction method is an effective and improved protocol for extraction of genomic DNA from microbial samples.

  7. What's Next After You Say Hello: First Steps in Mentoring

    Science.gov (United States)

    Hogue, William F.; Pringle, Ernest M.

    2005-01-01

    In most cultures wisdom, knowledge, and experience are prized assets. Those who possess them are held in high regard and are expected to share them with the next generation. So it is in the world of information technology (IT). Veteran IT professionals are often charged with identifying and developing future IT leaders, while future leaders often…

  8. Taking the Next Step: Confronting the Legacies of Slavery at Historic Sites

    Science.gov (United States)

    Grim, Linnea; Wickens, K. Allison; Jecha, Jackie; Powell, Linda; Hawkins, Callie; Flanagan, Candra

    2017-01-01

    "Slavery is the ground zero of race relations," declared James and Lois Horton in their groundbreaking book, "Slavery and Public History." Engaging the history and legacy of slavery is a crucial step in understanding current U.S. society especially race relations. Historic sites that have connections to slavery have begun to…

  9. The Next Generation Science Standards: The Features and Challenges

    Science.gov (United States)

    Pruitt, Stephen L.

    2014-01-01

    Beginning in January of 2010, the Carnegie Corporation of New York funded a two-step process to develop a new set of state developed science standards intended to prepare students for college and career readiness in science. These new internationally benchmarked science standards, the Next Generation Science Standards (NGSS) were completed in…

  10. Standardization and quality management in next-generation sequencing.

    Science.gov (United States)

    Endrullat, Christoph; Glökler, Jörn; Franke, Philipp; Frohme, Marcus

    2016-09-01

    DNA sequencing continues to evolve quickly even after > 30 years. Many new platforms suddenly appeared and former established systems have vanished in almost the same manner. Since establishment of next-generation sequencing devices, this progress gains momentum due to the continually growing demand for higher throughput, lower costs and better quality of data. In consequence of this rapid development, standardized procedures and data formats as well as comprehensive quality management considerations are still scarce. Here, we listed and summarized current standardization efforts and quality management initiatives from companies, organizations and societies in form of published studies and ongoing projects. These comprise on the one hand quality documentation issues like technical notes, accreditation checklists and guidelines for validation of sequencing workflows. On the other hand, general standard proposals and quality metrics are developed and applied to the sequencing workflow steps with the main focus on upstream processes. Finally, certain standard developments for downstream pipeline data handling, processing and storage are discussed in brief. These standardization approaches represent a first basis for continuing work in order to prospectively implement next-generation sequencing in important areas such as clinical diagnostics, where reliable results and fast processing is crucial. Additionally, these efforts will exert a decisive influence on traceability and reproducibility of sequence data.

  11. Tritium retention in candidate next-step protection materials: engineering key issues and research requirements

    International Nuclear Information System (INIS)

    Federici, G.; Andrew, P.L.; Wu, C.H.

    1995-01-01

    Although a considerable volume of valuable data on the behaviour of tritium in beryllium and carbon-based armours exposed to hydrogenic fusion plasmas has been compiled over the past years both from operation of present-day tokamaks and from laboratory simulations, knowledge is far from complete and tritium inventory predictions for these materials remain highly uncertain. In this paper we elucidate the main mechanisms responsible for tritium trapping and release in next-step D-T tokamaks, as well as the applicability of some of the presently known data bases for design purposes. Owing to their strong anticipated implications on tritium uptake and release, attention is focused mainly on the interaction of tritium with neutron damage induced defects, on tritium codeposition with eroded carbon and on the effects of oxide and surface contaminants. Some preliminary quantitative estimates are presented based on most recent experimental findings and latest modelling developments as well. The influence of important working conditions such as target temperature, loading particle fluxes, erosion and redeposition rates, as well as material characteristics such as the type of morphology of the protection material (i.e. amorphous plasma-sprayed beryllium vs. solid forms), and design dependent parameters are discussed in this paper. Remaining issues which require additional effort are identified. (orig.)

  12. The State of the Art. Bridge Protective Systems and Devices.

    Science.gov (United States)

    1978-10-01

    FOR 19=1 TO L4 STEP 1 1255 LET J=(I-1)*14+1 1268 LET LS=J+13 1265 LET L5=INT( L53 1278 FOR J9=J TO L5 STEP 1 1275 READ :1,"(J9) 1277 NEXT J9 1288 NEXT...T=R 2960 MAT R=T*B 2976 MAT T=R 2986 MAT R= TD 2996 "AT T=R 308 MAT R=T*E 3010 RE

  13. Getting Ahead Three Steps to Take Your Career to the Next Level

    CERN Document Server

    Garfinkle, Joel A

    2011-01-01

    A leading executive coach pinpoints three vital traits necessary to advance your career In Getting Ahead, one of the top 50 executive coaches in the United States, Joel Garfinkle reveals his signature model for mastering three skills to take your career to the next level: Perception, Visibility, and Influence. The PVI-model of professional advancement will teach you to: (1) Actively promote yourself as an asset and valuable person inside the organization, (2) Increase your visibility to gain others' recognition and appreciation for your efforts and (3) Become a person of influence who makes ke

  14. The quest for the next information processing technology

    Science.gov (United States)

    Welser, Jeffrey J.; Bourianoff, George I.; Zhirnov, Victor V.; Cavin, Ralph Keary

    2008-01-01

    Fundamental physical considerations indicate that the scaling of devices that use electron charge as the information carrier will limit within the next one to two decades. The Nanoelectronics Research Initiative (NRI), a joint industry-government program, has been developed to fund university research seeking devices that utilize alternative physical information carriers or non-equilibrium switching mechanisms to continue the historical cost and performance trends of information technology. Three research centers have been established to pursue five research vectors that have been identified as critical to the effort to replace the electronic switch. A brief history and rationale for NRI is given and the projects currently underway are described in the context of the five research vectors.

  15. Trapping of antiprotons -- a first step on the way to antihydrogen

    International Nuclear Information System (INIS)

    Holzscheiter, M.H.

    1993-01-01

    A first step towards producing and effectively utilizing antihydrogen atoms consists of trapping antiprotons. The immediate next step must then be to control, i.e. trap the produced antihydrogen. The current state of the art in trapping antiprotons and positrons is reviewed, and the challenges in trapping the resulting neutral particles are discussed

  16. Silicon on ferroelectic insulator field effect transistor (SOF-FET) a new device for the next generation ultra low power circuits

    Science.gov (United States)

    Es-Sakhi, Azzedin D.

    Field effect transistors (FETs) are the foundation for all electronic circuits and processors. These devices have progressed massively to touch its final steps in sub-nanometer level. Left and right proposals are coming to rescue this progress. Emerging nano-electronic devices (resonant tunneling devices, single-atom transistors, spin devices, Heterojunction Transistors rapid flux quantum devices, carbon nanotubes, and nanowire devices) took a vast share of current scientific research. Non-Si electronic materials like III-V heterostructure, ferroelectric, carbon nanotubes (CNTs), and other nanowire based designs are in developing stage to become the core technology of non-classical CMOS structures. FinFET present the current feasible commercial nanotechnology. The scalability and low power dissipation of this device allowed for an extension of silicon based devices. High short channel effect (SCE) immunity presents its major advantage. Multi-gate structure comes to light to improve the gate electrostatic over the channel. The new structure shows a higher performance that made it the first candidate to substitute the conventional MOSFET. The device also shows a future scalability to continue Moor's Law. Furthermore, the device is compatible with silicon fabrication process. Moreover, the ultra-low-power (ULP) design required a subthreshold slope lower than the thermionic-emission limit of 60mV/ decade (KT/q). This value was unbreakable by the new structure (SOI-FinFET). On the other hand most of the previews proposals show the ability to go beyond this limit. However, those pre-mentioned schemes have publicized a very complicated physics, design difficulties, and process non-compatibility. The objective of this research is to discuss various emerging nano-devices proposed for ultra-low-power designs and their possibilities to replace the silicon devices as the core technology in the future integrated circuit. This thesis proposes a novel design that exploits the

  17. Improving a 1 meter telescope in order to follow giant planets in a pro-am collaboration. Next step : an affordable adaptive optic system.=

    Science.gov (United States)

    Dauvergne, J.-L.; Colas, F.; Delcroix, M.; Lecacheux, J.

    2017-09-01

    We already have very good result with the 1 meter telescope of Pic du Midi. Our goal is to have more and more people in the team in order to make a survey has long as possible of Jupiter, Uranus and Neptune. The next step is an OA system, we want to make it work on the 1 meter telescope and also make it available on the market to help other observatories to produce high resolution images of the solar system with middle size telescopes.

  18. Configurable multi-step linear feedback shift register

    NARCIS (Netherlands)

    2010-01-01

    The state transition of a linear feedback shift register (LFSR) controlled by a clock (310) with length N and step size W, W being at least two, is accomplished via a next-state function (320). The next-state function deploys a state transition matrix (350). The state vector (330), which represents

  19. The "Next Generation Science Standards" and the Earth and Space Sciences

    Science.gov (United States)

    Wysession, Michael E.

    2013-01-01

    The "Next Generation Science Standards" ("NGSS"), due to be released this spring, represents a revolutionary step toward establishing modern, national K-12 science education standards. Based on the recommendations of the National Research Council's "A Framework for K-12 Science Education: Practices, Crosscutting…

  20. Engaging Students: The Next Level of Working on the Work

    Science.gov (United States)

    Schlechty, Phillip C.

    2011-01-01

    In Phillip Schlechty's best-selling book "Working on the Work", he outlined a motivational framework for improving student performance by improving the quality of schools designed for students. "Engaging Students" offers a next-step resource in which Schlechty incorporates what he's learned from the field and from the hundreds of workshops he and…

  1. The "Next Generation Science Standards" and the Earth and Space Sciences

    Science.gov (United States)

    Wysession, Michael E.

    2013-01-01

    In this article, Michael E. Wysession comments on the "Next Generation Science Standards" (NGSS), which are based on the recommendations of the National Research Council and represent a revolutionary step toward establishing modern, national K-12 science education standards. The NGSS involves significant changes from traditional…

  2. Control system devices : architectures and supply channels overview.

    Energy Technology Data Exchange (ETDEWEB)

    Trent, Jason; Atkins, William Dee; Schwartz, Moses Daniel; Mulder, John C.

    2010-08-01

    This report describes a research project to examine the hardware used in automated control systems like those that control the electric grid. This report provides an overview of the vendors, architectures, and supply channels for a number of control system devices. The research itself represents an attempt to probe more deeply into the area of programmable logic controllers (PLCs) - the specialized digital computers that control individual processes within supervisory control and data acquisition (SCADA) systems. The report (1) provides an overview of control system networks and PLC architecture, (2) furnishes profiles for the top eight vendors in the PLC industry, (3) discusses the communications protocols used in different industries, and (4) analyzes the hardware used in several PLC devices. As part of the project, several PLCs were disassembled to identify constituent components. That information will direct the next step of the research, which will greatly increase our understanding of PLC security in both the hardware and software areas. Such an understanding is vital for discerning the potential national security impact of security flaws in these devices, as well as for developing proactive countermeasures.

  3. Embedded Volttron specification - benchmarking small footprint compute device for Volttron

    Energy Technology Data Exchange (ETDEWEB)

    Sanyal, Jibonananda [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Fugate, David L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Woodworth, Ken [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Nutaro, James J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Kuruganti, Teja [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-08-17

    An embedded system is a small footprint computing unit that typically serves a specific purpose closely associated with measurements and control of hardware devices. These units are designed for reasonable durability and operations in a wide range of operating conditions. Some embedded systems support real-time operations and can demonstrate high levels of reliability. Many have failsafe mechanisms built to handle graceful shutdown of the device in exception conditions. The available memory, processing power, and network connectivity of these devices are limited due to the nature of their specific-purpose design and intended application. Industry practice is to carefully design the software for the available hardware capability to suit desired deployment needs. Volttron is an open source agent development and deployment platform designed to enable researchers to interact with devices and appliances without having to write drivers themselves. Hosting Volttron on small footprint embeddable devices enables its demonstration for embedded use. This report details the steps required and the experience in setting up and running Volttron applications on three small footprint devices: the Intel Next Unit of Computing (NUC), the Raspberry Pi 2, and the BeagleBone Black. In addition, the report also details preliminary investigation of the execution performance of Volttron on these devices.

  4. Methane emissions from the global oil and gas supply chain: recent advances and next steps

    Science.gov (United States)

    Zavala Araiza, D.; Herndon, S. C.; Roscioli, J. R.; Yacovitch, T. I.; Knighton, W. B.; Johnson, M.; Tyner, D. R.; Hamburg, S.

    2017-12-01

    A wide body of research has characterized methane emissions from the oil and gas system in the US. In contrast, empirical data is limited for other significant oil and gas producing regions across the world. As a consequence, measuring and characterizing methane emissions across global oil and gas operations will be crucial to the design of effective mitigation strategies. Several countries have announced pledges to reduce methane emissions from this system (e.g., North America, Climate and Clean Air Coalition [CCAC] ministers). In the case of Canada, the federal government recently announced regulations supporting a 40-45% reduction of methane emissions from the oil and gas production systems. For these regulations to be effective, it is critical to understand the current methane emission patterns. We present results from a coordinated multiscale (i.e., airborne-based, ground-based) measurement campaign in Alberta, Canada. We use empirically derived emission estimates to characterize site-level emissions and derive an emissions distribution. Our work shows that many major sources of emissions are unmeasured or underreported. Consistent with previous studies in the US, a small fraction of sites disproportionately account for the majority of emissions: roughly 20% of sites accounted for 75% of emissions. An independent airborne-based regional estimate was 40% lower than the ground-based regional estimate, but not statistically different. Finally, we summarize next steps as part of the CCAC Oil and Gas Methane Study: ongoing work that is targeting oil and gas sectors/production regions with limited empirical data on methane emissions. This work builds on the approach deployed in quantifying methane emissions from the oil and gas supply chain in the US, underscoring the commitment to transparency of the collected data, external review, deployment of multiple methodologies, and publication of results in peer-reviewed journals.

  5. Fabrication of micro- and nanometre-scale polymer structures in liquid crystal devices for next generation photonics applications

    Science.gov (United States)

    Tartan, Chloe C.; Salter, Patrick S.; Booth, Martin J.; Morris, Stephen M.; Elston, Steve J.

    2016-09-01

    Direct Laser Writing (DLW) by two-photon photopolymerization (TPP) enables the fabrication of micron-scale polymeric structures in soft matter systems. The technique has implications in a broad range of optics and photonics; in particular fast-switching liquid crystal (LC) modes for the development of next generation display technologies. In this paper, we report two different methodologies using our TPP-based fabrication technique. Two explicit examples are provided of voltage-dependent LC director profiles that are inherently unstable, but which appear to be promising candidates for fast-switching photonics applications. In the first instance, 1 μm-thick periodic walls of polymer network are written into a planar aligned (parallel rubbed) nematic pi-cell device containing a nematic LC-monomer mixture. The structures are fabricated when the device is electrically driven into a fast-switching nematic LC state and aberrations induced by the device substrates are corrected for by virtue of the adaptive optics elements included within the DLW setup. Optical polarizing microscopy images taken post-fabrication reveal that polymer walls oriented perpendicular to the rubbing direction promote the stability of the so-called optically compensated bend mode upon removal of the externally applied field. In the second case, polymer walls are written in a nematic LC-optically adhesive glue mixture. A polymer- LCs-polymer-slices or `POLICRYPS' template is formed by immersing the device in acetone post-fabrication to remove any remaining non-crosslinked material. Injecting the resultant series of polymer microchannels ( 1 μm-thick) with a short-pitch, chiral nematic LC mixture leads to the spontaneous alignment of a fast-switching chiral nematic mode, where the helical axis lies parallel to the glass substrates. Optimal contrast between the bright and dark states of the uniform lying helix alignment is achieved when the structures are spaced at the order of the device thickness

  6. Correction to “Advancing the Conversation: Next Steps for Lesbian, Gay, Bisexual, Trans, and Queer (LGBTQ Health Sciences Librarianship” on 105(4 October, page 325. DOI: http://dx.doi.org/10.5195/jmla.2017.206

    Directory of Open Access Journals (Sweden)

    Katherine G. Akers

    2018-01-01

    Full Text Available Corrects author name in reference #11 of “Advancing the Conversation: Next Steps For Lesbian, Gay, Bisexual, Trans, and Queer (LGBTQ Health Sciences Librarianship” on 105(4 October, page 325. DOI: http://dx.doi.org/10.5195/jmla.2017.206.

  7. Next steps

    Energy Technology Data Exchange (ETDEWEB)

    1980-01-01

    On the 60th anniversary of the founding of the Chartered Institute of Transport, its past, its current aims and structure, and the role which the Institute should adopt to the year 2000 are discussed. Technological and social change, bureaucracy, industrial relations, worker participation, government and transport, national role, and financial policy, are some of the subjects covered. In discussing the energy crisis, the objectives of the European Communities for 1985 and 1990 dealing with energy and energy conservatin are noted. Absent was the mention of the role that transport could play in the more efficient and effective utilization of energy. The Institute of Transport has the opportunity to demonstrate leadership and initiative in cooperating with governments in the area of energy use and energy conservation.

  8. Three-Dimensional Printing Based Hybrid Manufacturing of Microfluidic Devices.

    Science.gov (United States)

    Alapan, Yunus; Hasan, Muhammad Noman; Shen, Richang; Gurkan, Umut A

    2015-05-01

    Microfluidic platforms offer revolutionary and practical solutions to challenging problems in biology and medicine. Even though traditional micro/nanofabrication technologies expedited the emergence of the microfluidics field, recent advances in advanced additive manufacturing hold significant potential for single-step, stand-alone microfluidic device fabrication. One such technology, which holds a significant promise for next generation microsystem fabrication is three-dimensional (3D) printing. Presently, building 3D printed stand-alone microfluidic devices with fully embedded microchannels for applications in biology and medicine has the following challenges: (i) limitations in achievable design complexity, (ii) need for a wider variety of transparent materials, (iii) limited z-resolution, (iv) absence of extremely smooth surface finish, and (v) limitations in precision fabrication of hollow and void sections with extremely high surface area to volume ratio. We developed a new way to fabricate stand-alone microfluidic devices with integrated manifolds and embedded microchannels by utilizing a 3D printing and laser micromachined lamination based hybrid manufacturing approach. In this new fabrication method, we exploit the minimized fabrication steps enabled by 3D printing, and reduced assembly complexities facilitated by laser micromachined lamination method. The new hybrid fabrication method enables key features for advanced microfluidic system architecture: (i) increased design complexity in 3D, (ii) improved control over microflow behavior in all three directions and in multiple layers, (iii) transverse multilayer flow and precisely integrated flow distribution, and (iv) enhanced transparency for high resolution imaging and analysis. Hybrid manufacturing approaches hold great potential in advancing microfluidic device fabrication in terms of standardization, fast production, and user-independent manufacturing.

  9. Robotics: The next step?

    Science.gov (United States)

    Broeders, Ivo A M J

    2014-02-01

    Robotic systems were introduced 15 years ago to support complex endoscopic procedures. The technology is increasingly used in gastro-intestinal surgery. In this article, literature on experimental- and clinical research is reviewed and ergonomic issues are discussed. literature review was based on Medline search using a large variety of search terms, including e.g. robot(ic), randomized, rectal, oesophageal, ergonomics. Review articles on relevant topics are discussed with preference. There is abundant evidence of supremacy in performing complex endoscopic surgery tasks when using the robot in an experimental setting. There is little high-level evidence so far on translation of these merits to clinical practice. Robotic systems may appear helpful in complex gastro-intestinal surgery. Moreover, dedicated computer based technology integrated in telepresence systems opens the way to integration of planning, diagnostics and therapy. The first high tech add-ons such as near infrared technology are under clinical evaluation. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. Robotics: the next step?

    NARCIS (Netherlands)

    Broeders, Ivo Adriaan Maria Johannes; Kuipers, E.J.

    2014-01-01

    Abstract: Robotic systems were introduced 15 years ago to support complex endoscopic procedures. The technology is increasingly used in gastro-intestinal surgery. In this article, literature on experimental- and clinical research is reviewed and ergonomic issues are discussed. Methods: literature

  11. Alignment of Short Reads: A Crucial Step for Application of Next-Generation Sequencing Data in Precision Medicine

    Directory of Open Access Journals (Sweden)

    Hao Ye

    2015-11-01

    Full Text Available Precision medicine or personalized medicine has been proposed as a modernized and promising medical strategy. Genetic variants of patients are the key information for implementation of precision medicine. Next-generation sequencing (NGS is an emerging technology for deciphering genetic variants. Alignment of raw reads to a reference genome is one of the key steps in NGS data analysis. Many algorithms have been developed for alignment of short read sequences since 2008. Users have to make a decision on which alignment algorithm to use in their studies. Selection of the right alignment algorithm determines not only the alignment algorithm but also the set of suitable parameters to be used by the algorithm. Understanding these algorithms helps in selecting the appropriate alignment algorithm for different applications in precision medicine. Here, we review current available algorithms and their major strategies such as seed-and-extend and q-gram filter. We also discuss the challenges in current alignment algorithms, including alignment in multiple repeated regions, long reads alignment and alignment facilitated with known genetic variants.

  12. Design scoping study of the 12T Yin-Yang magnet system for the Tandem Mirror Next Step (TMNS). Final report

    International Nuclear Information System (INIS)

    1981-09-01

    The overall objective of this engineering study was to determine the feasibility of designing a Yin-Yang magnet capable of producing a peak field in the windings of 12T for the Tandem Mirror Next Step (TMNS) program. As part of this technical study, a rough order of magnitude (ROM) cost estimate of the winding for this magnet was undertaken. The preferred approach to the winding design of the TMNS plug coil utilizes innovative design concepts to meet the structural, electrical and thermodynamic requirements of the magnet system. Structurally, the coil is radially partitioned into four sections, preventing the accumulation of the radial loads and reacting them into the structural case. To safely dissipate the 13.34 GJ of energy stored in each Yin-Yang magnet, the winding has been electrically subdivided into parallel or nested coils, each having its own power supply and protection circuitry. This arrangement effectively divides the total stored energy of the coils into manageable subsystems. The windings are cooled with superfluid helium II, operated at 1.8K and 1.2 atmospheres. The superior cooling capabilities of helium II have enabled the overall winding envelope to be minimized, providing a current density of 2367 A/CM 2 , excluding substructure

  13. The next step for stress research in primates: To identify relationships between glucocorticoid secretion and fitness.

    Science.gov (United States)

    Beehner, Jacinta C; Bergman, Thore J

    2017-05-01

    Glucocorticoids are hormones that mediate the energetic demands that accompany environmental challenges. It is therefore not surprising that these metabolic hormones have come to dominate endocrine research on the health and fitness of wild populations. Yet, several problems have been identified in the vertebrate research that also apply to the non-human primate research. First, glucocorticoids should not be used as a proxy for fitness (unless a link has previously been established between glucocorticoids and fitness for a particular population). Second, stress research in behavioral ecology has been overly focused on "chronic stress" despite little evidence that chronic stress hampers fitness in wild animals. Third, research effort has been disproportionately focused on the causes of glucocorticoid variation rather than the fitness consequences. With these problems in mind, we have three objectives for this review. We describe the conceptual framework behind the "stress concept", emphasizing that high glucocorticoids do not necessarily indicate a stress response, and that a stress response does not necessarily indicate an animal is in poor health. Then, we conduct a comprehensive review of all studies on "stress" in wild primates, including any study that examined environmental factors, the stress response, and/or fitness (or proxies for fitness). Remarkably, not a single primate study establishes a connection between all three. Finally, we provide several recommendations for future research in the field of primate behavioral endocrinology, primarily the need to move beyond identifying the factors that cause glucocorticoid secretion to additionally focus on the relationship between glucocorticoids and fitness. We believe that this is an important next step for research on stress physiology in primates. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Video-Recorded Validation of Wearable Step Counters under Free-living Conditions.

    Science.gov (United States)

    Toth, Lindsay P; Park, Susan; Springer, Cary M; Feyerabend, McKenzie D; Steeves, Jeremy A; Bassett, David R

    2018-06-01

    The purpose of this study was to determine the accuracy of 14-step counting methods under free-living conditions. Twelve adults (mean ± SD age, 35 ± 13 yr) wore a chest harness that held a GoPro camera pointed down at the feet during all waking hours for 1 d. The GoPro continuously recorded video of all steps taken throughout the day. Simultaneously, participants wore two StepWatch (SW) devices on each ankle (all programmed with different settings), one activPAL on each thigh, four devices at the waist (Fitbit Zip, Yamax Digi-Walker SW-200, New Lifestyles NL-2000, and ActiGraph GT9X (AG)), and two devices on the dominant and nondominant wrists (Fitbit Charge and AG). The GoPro videos were downloaded to a computer and researchers counted steps using a hand tally device, which served as the criterion method. The SW devices recorded between 95.3% and 102.8% of actual steps taken throughout the day (P > 0.05). Eleven step counting methods estimated less than 100% of actual steps; Fitbit Zip, Yamax Digi-Walker SW-200, and AG with the moving average vector magnitude algorithm on both wrists recorded 71% to 91% of steps (P > 0.05), whereas the activPAL, New Lifestyles NL-2000, and AG (without low-frequency extension (no-LFE), moving average vector magnitude) worn on the hip, and Fitbit Charge recorded 69% to 84% of steps (P 0.05), whereas the AG (LFE) on both wrists and the hip recorded 128% to 220% of steps (P < 0.05). Across all waking hours of 1 d, step counts differ between devices. The SW, regardless of settings, was the most accurate method of counting steps.

  15. An evaluation of prefilled insulin pens: a focus on the Next Generation FlexPen®

    Directory of Open Access Journals (Sweden)

    Estella M Davis

    2010-08-01

    Full Text Available Estella M Davis, Emily L Sexson, Mikayla L Spangler, Pamela A ForalDepartment of Pharmacy Practice, Creighton University School of Pharmacy and Health Professions, Omaha, Nebraska, USAAbstract: Insulin pen delivery systems are preferred by patients over the traditional vial and syringe method for insulin delivery because they are simple and easy to use, improve confidence in dosing insulin, and have less interference with activities and improved discretion with use. Insulin manufacturers have made numerous improvements to their first marketed pen devices and are now introducing their next generation of devices. Design modifications to the newest generation of prefilled insulin pen devices are intended to improve the ease of use and safety and continue to positively impact adherence to insulin. This review focuses on the Next Generation FlexPen® with regard to design considerations to reduce injection force, improve accuracy and ease of use, and evaluate the preference of patient and health-care provider compared with other disposable, prefilled insulin pen devices.Keywords: diabetes, dose accuracy, injection force, patient preference, insulin pen device

  16. Thermonuclear ignition in the next generation tokamaks

    International Nuclear Information System (INIS)

    Johner, J.

    1989-04-01

    The extrapolation of experimental rules describing energy confinement and magnetohydrodynamic - stability limits, in known tokamaks, allow to show that stable thermonuclear ignition equilibria should exist in this configuration, if the product aB t x of the dimensions by a magnetic-field power is large enough. Quantitative application of this result to several next-generation tokamak projects show that those kinds of equilibria could exist in such devices, which would also have enough additional heating power to promote an effective accessible ignition

  17. Microfluidic step-emulsification in axisymmetric geometry.

    Science.gov (United States)

    Chakraborty, I; Ricouvier, J; Yazhgur, P; Tabeling, P; Leshansky, A M

    2017-10-25

    Biphasic step-emulsification (Z. Li et al., Lab Chip, 2015, 15, 1023) is a promising microfluidic technique for high-throughput production of μm and sub-μm highly monodisperse droplets. The step-emulsifier consists of a shallow (Hele-Shaw) microchannel operating with two co-flowing immiscible liquids and an abrupt expansion (i.e., step) to a deep and wide reservoir. Under certain conditions the confined stream of the disperse phase, engulfed by the co-flowing continuous phase, breaks into small highly monodisperse droplets at the step. Theoretical investigation of the corresponding hydrodynamics is complicated due to the complex geometry of the planar device, calling for numerical approaches. However, direct numerical simulations of the three dimensional surface-tension-dominated biphasic flows in confined geometries are computationally expensive. In the present paper we study a model problem of axisymmetric step-emulsification. This setup consists of a stable core-annular biphasic flow in a cylindrical capillary tube connected co-axially to a reservoir tube of a larger diameter through a sudden expansion mimicking the edge of the planar step-emulsifier. We demonstrate that the axisymmetric setup exhibits similar regimes of droplet generation to the planar device. A detailed parametric study of the underlying hydrodynamics is feasible via inexpensive (two dimensional) simulations owing to the axial symmetry. The phase diagram quantifying the different regimes of droplet generation in terms of governing dimensionless parameters is presented. We show that in qualitative agreement with experiments in planar devices, the size of the droplets generated in the step-emulsification regime is independent of the capillary number and almost insensitive to the viscosity ratio. These findings confirm that the step-emulsification regime is solely controlled by surface tension. The numerical predictions are in excellent agreement with in-house experiments with the axisymmetric

  18. Lunar Station: The Next Logical Step in Space Development

    Science.gov (United States)

    Pittman, Robert Bruce; Harper, Lynn; Newfield, Mark; Rasky, Daniel J.

    2014-01-01

    The International Space Station (ISS) is the product of the efforts of sixteen nations over the course of several decades. It is now complete, operational, and has been continuously occupied since November of 20001. Since then the ISS has been carrying out a wide variety of research and technology development experiments, and starting to produce some pleasantly startling results. The ISS has a mass of 420 metric tons, supports a crew of six with a yearly resupply requirement of around 30 metric tons, within a pressurized volume of 916 cubic meters, and a habitable volume of 388 cubic meters. Its solar arrays produce up to 84 kilowatts of power. In the course of developing the ISS, many lessons were learned and much valuable expertise was gained. Where do we go from here? The ISS offers an existence proof of the feasibility of sustained human occupation and operations in space over decades. It also demonstrates the ability of many countries to work collaboratively on a very complex and expensive project in space over an extended period of time to achieve a common goal. By harvesting best practices and lessons learned, the ISS can also serve as a useful model for exploring architectures for beyond low-­- earth-­-orbit (LEO) space development. This paper will explore the concept and feasibility for a Lunar Station. The Station concept can be implemented by either putting the equivalent capability of the ISS down on the surface of the Moon, or by developing the required capabilities through a combination of delivered materials and equipment and in situ resource utilization (ISRU). Scenarios that leverage existing technologies and capabilities as well as capabilities that are under development and are expected to be available within the next 3-­5 years, will be examined. This paper will explore how best practices and expertise gained from developing and operating the ISS and other relevant programs can be applied to effectively developing Lunar Station.

  19. Emerging Trends in Phosphorene Fabrication towards Next Generation Devices.

    Science.gov (United States)

    Dhanabalan, Sathish Chander; Ponraj, Joice Sophia; Guo, Zhinan; Li, Shaojuan; Bao, Qiaoliang; Zhang, Han

    2017-06-01

    The challenge of science and technology is to design and make materials that will dominate the future of our society. In this context, black phosphorus has emerged as a new, intriguing two-dimensional (2D) material, together with its monolayer, which is referred to as phosphorene. The exploration of this new 2D material demands various fabrication methods to achieve potential applications- this demand motivated this review. This article is aimed at supplementing the concrete understanding of existing phosphorene fabrication techniques, which forms the foundation for a variety of applications. Here, the major issue of the degradation encountered in realizing devices based on few-layered black phosphorus and phosphorene is reviewed. The prospects of phosphorene in future research are also described by discussing its significance and explaining ways to advance state-of-art of phosphorene-based devices. In addition, a detailed presentation on the demand for future studies to promote well-systemized fabrication methods towards large-area, high-yield and perfectly protected phosphorene for the development of reliable devices in optoelectronic applications and other areas is offered.

  20. Positioning Space Solar Power (SSP) as the Next Logical Step after the International Space Station (ISS)

    Science.gov (United States)

    Charania, A.

    2002-01-01

    At the end of the first decade of the 21st century, the International Space Station (ISS) will stand as a testament of the engineering capabilities of the international community. The choices for the next logical step for this community remain vast and conflicting: a Mars mission, moon colonization, Space Solar Power (SSP), etc. This examination focuses on positioning SSP as one such candidate for consideration. A marketing roadmap is presented that reveals the potential benefits of SSP to both the space community and the global populace at large. Recognizing that scientific efficiency itself has no constituency large enough to persuade entities to outlay funds for such projects, a holistic approach is taken to positioning SSP. This includes the scientific, engineering, exploratory, economic, political, and development capabilities of the system. SSP can be seen as both space exploration related and a resource project for undeveloped nations. Coupling these two non-traditional areas yields a broader constituency for the project that each one alone could generate. Space exploration is many times seen as irrelevant to the condition of the populace of the planet from which the money comes for such projects. When in this new century, billions of people on the planet still have never made a phone call or even have access to clean water, the origins of this skepticism can be understandable. An area of concern is the problem of not living up to the claims of overeager program marketers. Just as the ISS may never live up to the claims of its advocates in terms of space research, any SSP program must be careful in not promising utopian global solutions to any future energy starved world. Technically, SSP is a very difficult problem, even harder than creating the ISS, yet the promise it can hold for both space exploration and Earth development can lead to a renaissance of the relevance of space to the lives of the citizens of the world.

  1. FIRE, A Next Step Option for Magnetic Fusion

    International Nuclear Information System (INIS)

    Meade, D.M.

    2002-01-01

    The next major frontier in magnetic fusion physics is to explore and understand the strong nonlinear coupling among confinement, MHD stability, self-heating, edge physics, and wave-particle interactions that is fundamental to fusion plasma behavior. The Fusion Ignition Research Experiment (FIRE) Design Study has been undertaken to define the lowest cost facility to attain, explore, understand, and optimize magnetically confined fusion-dominated plasmas. The FIRE is envisioned as an extension of the existing Advanced Tokamak Program that could lead to an attractive magnetic fusion reactor. The FIRE activities have focused on the physics and engineering assessment of a compact, high-field tokamak with the capability of achieving Q approximately equal to 10 in the ELMy H-mode for a duration of about 1.5 plasma current redistribution times (skin times) during an initial burning-plasma science phase, and the flexibility to add Advanced Tokamak hardware (e.g., lower-hybrid current drive) later. The configuration chosen for FIRE is similar to that of ARIES-RS, the U.S. Fusion Power Plant study utilizing an Advanced Tokamak reactor. The key ''Advanced Tokamak'' features are: strong plasma shaping, double-null pumping divertors, low toroidal field ripple ( 5) for a duration of 1 to 3 current redistribution times

  2. Cell motility regulation on a stepped micro pillar array device (SMPAD) with a discrete stiffness gradient.

    Science.gov (United States)

    Lee, Sujin; Hong, Juhee; Lee, Junghoon

    2016-02-28

    Our tissues consist of individual cells that respond to the elasticity of their environment, which varies between and within tissues. To better understand mechanically driven cell migration, it is necessary to manipulate the stiffness gradient across a substrate. Here, we have demonstrated a new variant of the microfabricated polymeric pillar array platform that can decouple the stiffness gradient from the ECM protein area. This goal is achieved via a "stepped" micro pillar array device (SMPAD) in which the contact area with the cell was kept constant while the diameter of the pillar bodies was altered to attain the proper mechanical stiffness. Using double-step SU-8 mold fabrication, the diameter of the top of every pillar was kept uniform, whereas that of the bottom was changed, to achieve the desired substrate rigidity. Fibronectin was immobilized on the pillar tops, providing a focal adhesion site for cells. C2C12, HeLa and NIH3T3 cells were cultured on the SMPAD, and the motion of the cells was observed by time-lapse microscopy. Using this simple platform, which produces a purely physical stimulus, we observed that various types of cell behavior are affected by the mechanical stimulus of the environment. We also demonstrated directed cell migration guided by a discrete rigidity gradient by varying stiffness. Interestingly, cell velocity was highest at the highest stiffness. Our approach enables the regulation of the mechanical properties of the polymeric pillar array device and eliminates the effects of the size of the contact area. This technique is a unique tool for studying cellular motion and behavior relative to various stiffness gradients in the environment.

  3. Electronic module for control of sample feeding device of spectrometers of X-ray fluorescent analysis of CRV type

    International Nuclear Information System (INIS)

    Petrov, V.A.; Fursov, A.V.

    2002-01-01

    The scheme of electronic module for sample feeding device control for the CRV type X-ray fluorescence analysis spectrometers is considered. This module provides realization of next functions: sample change operations and installation in starting position; signaling and defense at emergency cases; indication of any sample amount in the spectrometer chamber; testing function at tuning and testing of modules. All these principal functions are entrusted with microcontroller. Programming of the microcontroller is putting into effect by algorithm of the whole sample feeding device. In the capacity of microcontroller the single crystalline processor PICI16C54 and stepping motor of NV-306-V2202 model have been used

  4. Computational Abstraction Steps

    DEFF Research Database (Denmark)

    Thomsen, Lone Leth; Thomsen, Bent; Nørmark, Kurt

    2010-01-01

    and class instantiations. Our teaching experience shows that many novice programmers find it difficult to write programs with abstractions that materialise to concrete objects later in the development process. The contribution of this paper is the idea of initiating a programming process by creating...... or capturing concrete values, objects, or actions. As the next step, some of these are lifted to a higher level by computational means. In the object-oriented paradigm the target of such steps is classes. We hypothesise that the proposed approach primarily will be beneficial to novice programmers or during...... the exploratory phase of a program development process. In some specific niches it is also expected that our approach will benefit professional programmers....

  5. Virtual MIMO Beamforming and Device Pairing Enabled by Device-to-Device Communications for Multidevice Networks

    Directory of Open Access Journals (Sweden)

    Yeonjin Jeong

    2017-01-01

    Full Text Available We consider a multidevice network with asymmetric antenna configurations which supports not only communications between an access point and devices but also device-to-device (D2D communications for the Internet of things. For the network, we propose the transmit and receive beamforming with the channel state information (CSI for virtual multiple-input multiple-output (MIMO enabled by D2D receive cooperation. We analyze the sum rate achieved by a device pair in the proposed method and identify the strategies to improve the sum rate of the device pair. We next present a distributed algorithm and its equivalent algorithm for device pairing to maximize the throughput of the multidevice network. Simulation results confirm the advantages of the transmit CSI and D2D cooperation as well as the validity of the distributive algorithm.

  6. Reconciling proteomics with next generation sequencing

    NARCIS (Netherlands)

    Low, Teck Yew; Heck, Albert Jr

    2015-01-01

    Both genomics and proteomics technologies have matured in the last decade to a level where they are able to deliver system-wide data on the qualitative and quantitative abundance of their respective molecular entities, that is DNA/RNA and proteins. A next logical step is the collective use of these

  7. Heterostructures and quantum devices

    CERN Document Server

    Einspruch, Norman G

    1994-01-01

    Heterostructure and quantum-mechanical devices promise significant improvement in the performance of electronic and optoelectronic integrated circuits (ICs). Though these devices are the subject of a vigorous research effort, the current literature is often either highly technical or narrowly focused. This book presents heterostructure and quantum devices to the nonspecialist, especially electrical engineers working with high-performance semiconductor devices. It focuses on a broad base of technical applications using semiconductor physics theory to develop the next generation of electrical en

  8. Material and Phonon Engineering for Next Generation Acoustic Devices

    Science.gov (United States)

    Kuo, Nai-Kuei

    This thesis presents the theoretical and experimental work related to micromachining of low intrinsic loss sapphire and phononic crystals for engineering new classes of electroacoustic devices for frequency control applications. For the first time, a low loss sapphire suspended membrane was fabricated and utilized to form the main body of a piezoelectric lateral overtone bulk acoustic resonator (LOBAR). Since the metalized piezoelectric transducer area in a LOBAR is only a small fraction of the overall resonant cavity (made out of sapphire), high quality factor (Q) overtones are attained. The experiment confirms the low intrinsic mechanical loss of the transferred sapphire thin film, and the resonators exhibit the highest Q of 5,440 at 2.8 GHz ( f·Q of 1.53.1013 Hz). This is also the highest f·Q demonstrated for aluminum-nitride-(AIN)-based Lamb wave devices to date. Beyond demonstrating a low loss device, this experimental work has laid the foundation for the future development of new micromechanical devices based on a high Q, high hardness and chemically resilient material. The search for alternative ways to more efficiently perform frequency control functionalities lead to the exploration of Phononic Crystal (PnC) structures in AIN thin films. Four unit cell designs were theoretically and experimentally investigated to explore the behavior of phononic bandgaps (PBGs) in the ultra high frequency (UHF) range: (i) the conventional square lattice with circular air scatterer, (ii) the inverse acoustic bandgap (IABG) structure, (iii) the fractal PnC, and (iv) the X-shaped PnC. Each unit cell has its unique frequency characteristic that was exploited to synthesize either cavity resonators or improve the performance of acoustic delay lines. The PBGs operate in the range of 770 MHz to 1 GHz and exhibit a maximum acoustic rejection of 40 dB. AIN Lamb wave transducers (LWTs) were employed for the experimental demonstration of the PBGs and cavity resonances. Ultra

  9. NASA's Commercial Crew Program, The Next Step in U.S. Space Transportation

    Science.gov (United States)

    Mango, Edward J.; Thomas, Rayelle E.

    2013-01-01

    The Commercial Crew Program (CCP) is leading NASA's efforts to develop the next U.S. capability for crew transportation and rescue services to and from the International Space Station (ISS) by the mid-decade timeframe. The outcome of this capability is expected to stimulate and expand the U.S. space transportation industry. NASA is relying on its decades of human space flight experience to certify U.S. crewed vehicles to the ISS and is doing so in a two phase certification approach. NASA Certification will cover all aspects of a crew transportation system, including development, test, evaluation, and verification; program management and control; flight readiness certification; launch, landing, recovery, and mission operations; sustaining engineering and maintenance/upgrades. To ensure NASA crew safety, NASA Certification will validate technical and performance requirements, verify compliance with NASA requirements, validate the crew transportation system operates in appropriate environments, and quantify residual risks.

  10. Tritium retention in next step devices and the requirements for mitigation and removal techniques

    International Nuclear Information System (INIS)

    Counsell, G; Coad, P; Grisola, C; Hopf, C

    2006-01-01

    Mechanisms underlying the retention of fuel species in tokamaks with carbon plasma-facing components are presented, together with estimates for the corresponding retention of tritium in ITER. The consequential requirement for new and improved schemes to reduce the tritium inventory is highlighted and the results of ongoing studies into a range of techniques are presented, together with estimates of the tritium removal rate in ITER in each case. Finally, an approach involving the integration of many tritium removal techniques into the ITER operational schedule is proposed as a means to extend the period of operations before major intervention is required

  11. The Satellite Test of the Equivalence Principle (STEP)

    Science.gov (United States)

    2004-01-01

    STEP will carry concentric test masses to Earth orbit to test a fundamental assumption underlying Einstein's theory of general relativity: that gravitational mass is equivalent to inertial mass. STEP is a 21st-century version of the test that Galileo is said to have performed by dropping a carnon ball and a musket ball simultaneously from the top of the Leaning Tower of Pisa to compare their accelerations. During the STEP experiment, four pairs of test masses will be falling around the Earth, and their accelerations will be measured by superconducting quantum interference devices (SQUIDS). The extended time sensitivity of the instruments will allow the measurements to be a million times more accurate than those made in modern ground-based tests.

  12. Next-to-next-to-eikonal corrections in the CGC

    Energy Technology Data Exchange (ETDEWEB)

    Altinoluk, Tolga; Armesto, Néstor [Departamento de Física de Partículas and IGFAE,Universidade de Santiago de Compostela,E-15706 Santiago de Compostela, Galicia (Spain); Beuf, Guillaume [Department of Physics, Ben-Gurion University of the Negev,Beer Sheva 84105 (Israel); Moscoso, Alexis [Departamento de Física de Partículas and IGFAE,Universidade de Santiago de Compostela,E-15706 Santiago de Compostela, Galicia (Spain)

    2016-01-19

    We extend the study of corrections to the eikonal approximation that was initiated in ref. http://dx.doi.org/10.1007/JHEP07(2014)068 to higher orders. These corrections associated with the finite width of the target are investigated and the gluon propagator in background field is calculated at next-to-next-to-eikonal accuracy. The result is then applied to the single inclusive gluon production cross section at central rapidities and the single transverse spin asymmetry with a transversely polarized target, in pA collisions, in order to analyze these observables beyond the eikonal limit. The next-to-next-to-eikonal corrections to the unpolarized cross section are non-zero and provide the first corrections to the usual k{sub ⊥}-factorized expression. In contrast, the eikonal and next-to-next-to-eikonal contributions to the single transverse spin asymmetry vanish, while the next-to-eikonal ones are non-zero.

  13. Secure-Network-Coding-Based File Sharing via Device-to-Device Communication

    OpenAIRE

    Wang, Lei; Wang, Qing

    2017-01-01

    In order to increase the efficiency and security of file sharing in the next-generation networks, this paper proposes a large scale file sharing scheme based on secure network coding via device-to-device (D2D) communication. In our scheme, when a user needs to share data with others in the same area, the source node and all the intermediate nodes need to perform secure network coding operation before forwarding the received data. This process continues until all the mobile devices in the netw...

  14. Designs and Architectures for the Next Generation of Organic Solar Cells

    Directory of Open Access Journals (Sweden)

    Kang-Shyang Liao

    2010-06-01

    Full Text Available Organic solar cells show great promise as an economically and environmentally friendly technology to utilize solar energy because of their simple fabrication processes and minimal material usage. However, new innovations and breakthroughs are needed for organic solar cell technology to become competitive in the future. This article reviews research efforts and accomplishments focusing on three issues: power conversion efficiency, device stability and processability for mass production, followed by an outlook for optimizing OSC performance through device engineering and new architecture designs to realize next generation organic solar cells.

  15. Helical-type device and laser fusion. Rivals for tokamak-type device at n-fusion development in Japan

    International Nuclear Information System (INIS)

    Anon.

    1994-01-01

    Under the current policy on the research and development of nuclear fusion in Japan, as enunciated by the Atomic Energy Commission of Japan, the type of a prototype fusion reactor will be chosen after 2020 from tokamak, helical or some other type including the inertial confinement fusion using lasers. A prototype fusion reactor is the next step following the tokamak type International Thermonuclear Experimental Reactor (ITER). With the prototype reactor, the feasibility as a power plant will be examined. At present the main research and development of nuclear fusion in Japan are on tokamak type, which have been promoted by Japan Atomic Energy Research Institute (JAERI). As for the other types of nuclear fusion, researches have been carried out on the helical type in Kyoto University and National Institute for Fusion Science (NIFS), the mirror type in Tsukuba University, the tokamak type using superconductive coils in Kyushu University, and the laser fusion in Osaka University. The features and the present state of research and development of the Large Helical Device and the laser fusion which is one step away from the break-even condition are reported. (K.I.)

  16. High aspect-ratio MEMS devices for the next generation of THz/MHz passive components

    NARCIS (Netherlands)

    Fiorentino, G.

    2015-01-01

    The realization of efficient passive devices directly on chip represents one of the most intriguing challenges in IC fabrication processes. The performance of such devices are intrinsically determined by physical parameters that cannot be easily scaled, making the on-chip integration of such

  17. Domestic and foreign trends in the prevalence of heart failure and the necessity of next-generation artificial hearts: a survey by the Working Group on Establishment of Assessment Guidelines for Next-Generation Artificial Heart Systems.

    Science.gov (United States)

    Tatsumi, Eisuke; Nakatani, Takeshi; Imachi, Kou; Umezu, Mitsuo; Kyo, Shun-Ei; Sase, Kazuhiro; Takatani, Setsuo; Matsuda, Hikaru

    2007-01-01

    A series of guidelines for development and assessment of next-generation medical devices has been drafted under an interagency collaborative project by the Ministry of Health, Labor and Welfare and the Ministry of Economy, Trade and Industry. The working group for assessment guidelines of next-generation artificial hearts reviewed the trend in the prevalence of heart failure and examined the potential usefulness of such devices in Japan and in other countries as a fundamental part of the process of establishing appropriate guidelines. At present, more than 23 million people suffer from heart failure in developed countries, including Japan. Although Japan currently has the lowest mortality from heart failure among those countries, the number of patients is gradually increasing as our lifestyle becomes more Westernized; the associated medical expenses are rapidly growing. The number of heart transplantations, however, is limited due to the overwhelming shortage of donor hearts, not only in Japan but worldwide. Meanwhile, clinical studies and surveys have revealed that the major causes of death in patients undergoing long-term use of ventricular assist devices (VADs) were infection, thrombosis, and mechanical failure, all of which are typical of VADs. It is therefore of urgent and universal necessity to develop next-generation artificial hearts that have excellent durability to provide at least 2 years of event-free operation with a superior quality of life and that can be used for destination therapy to save patients with irreversible heart failure. It is also very important to ensure that an environment that facilitates the development, testing, and approval evaluation processes of next-generation artificial hearts be established as soon as possible.

  18. Trainer variability during step training after spinal cord injury: Implications for robotic gait-training device design.

    Science.gov (United States)

    Galvez, Jose A; Budovitch, Amy; Harkema, Susan J; Reinkensmeyer, David J

    2011-01-01

    Robotic devices are being developed to automate repetitive aspects of walking retraining after neurological injuries, in part because they might improve the consistency and quality of training. However, it is unclear how inconsistent manual training actually is or whether stepping quality depends strongly on the trainers' manual skill. The objective of this study was to quantify trainer variability of manual skill during step training using body-weight support on a treadmill and assess factors of trainer skill. We attached a sensorized orthosis to one leg of each patient with spinal cord injury and measured the shank kinematics and forces exerted by different trainers during six training sessions. An expert trainer rated the trainers' skill level based on videotape recordings. Between-trainer force variability was substantial, about two times greater than within-trainer variability. Trainer skill rating correlated strongly with two gait features: better knee extension during stance and fewer episodes of toe dragging. Better knee extension correlated directly with larger knee horizontal assistance force, but better toe clearance did not correlate with larger ankle push-up force; rather, it correlated with better knee and hip extension. These results are useful to inform robotic gait-training design.

  19. Sound pressure levels generated at risk volume steps of portable listening devices: types of smartphone and genres of music.

    Science.gov (United States)

    Kim, Gibbeum; Han, Woojae

    2018-05-01

    The present study estimated the sound pressure levels of various music genres at the volume steps that contemporary smartphones deliver, because these levels put the listener at potential risk for hearing loss. Using six different smartphones (Galaxy S6, Galaxy Note 3, iPhone 5S, iPhone 6, LG G2, and LG G3), the sound pressure levels for three genres of K-pop music (dance-pop, hip-hop, and pop-ballad) and a Billboard pop chart of assorted genres were measured through an earbud for the first risk volume that was at the risk sign proposed by the smartphones, as well as consecutive higher volumes using a sound level meter and artificial mastoid. The first risk volume step of the Galaxy S6 and the LG G2, among the six smartphones, had the significantly lowest (84.1 dBA) and highest output levels (92.4 dBA), respectively. As the volume step increased, so did the sound pressure levels. The iPhone 6 was loudest (113.1 dBA) at the maximum volume step. Of the music genres, dance-pop showed the highest output level (91.1 dBA) for all smartphones. Within the frequency range of 20~ 20,000 Hz, the sound pressure level peaked at 2000 Hz for all the smartphones. The results showed that the sound pressure levels of either the first volume step or the maximum volume step were not the same for the different smartphone models and genres of music, which means that the risk volume sign and its output levels should be unified across the devices for their users. In addition, the risk volume steps proposed by the latest smartphone models are high enough to cause noise-induced hearing loss if their users habitually listen to music at those levels.

  20. Carrier ethernet network control plane based on the Next Generation Network

    DEFF Research Database (Denmark)

    Fu, Rong; Wang, Yanmeng; Berger, Michael Stubert

    2008-01-01

    This paper contributes on presenting a step towards the realization of Carrier Ethernet control plane based on the next generation network (NGN). Specifically, transport MPLS (T-MPLS) is taken as the transport technology in Carrier Ethernet. It begins with providing an overview of the evolving...... architecture of the next generation network (NGN). As an essential candidate among the NGN transport technologies, the definition of Carrier Ethernet (CE) is also introduced here. The second part of this paper depicts the contribution on the T-MPLS based Carrier Ethernet network with control plane based on NGN...... at illustrating the improvement of the Carrier Ethernet network with the NGN control plane....

  1. Development of fluidic device in SIT for Korean Next Generation Reactor I

    International Nuclear Information System (INIS)

    Cho, Bong Hyun; Lee, Joon; Bae, Yoon Young; Park, Jong Kyun

    1999-07-01

    The KNGR is to install a Fluidic Device at the bottom of the inner space of the SIT (Safety Injection Tank) to control the flow rate of safety injection coolant from SIT during LBLOCA. During the past two years, a scale model test to obtain the required flow characteristics of the device under the KNGR specific conditions has been performed using the experience and existing facility of AEA Technology (UK) with appropriate modifications. The performance verification test is to be performed this year to obtain optimum characteristics and design data of full size fluidic device. The purpose of the model test was to check the feasibility of developing the device and to produce a generic flow characteristic data. The test was performed in approximately 1/7 scale in terms of flow rate with full height and pressure. This report presents the details of system performance requirements for the device, design procedure for the fluidic device to be used, test facility and test method. The time dependent flow, pressure and Euler number are presented as characteristics curves and the most stable and the most effective flow control characteristic parameters were recommended through the evaluation. A method to predict the size of the fluidic device is presented. And a sizing algorithm, which can be used to conveniently determine the major geometric data of the device for various operating conditions, and a FORTRAN program to produce the prediction of performance curves have been developed. (author). 32 refs., 15 tabs., 47 figs

  2. Strong Stability Preserving Explicit Linear Multistep Methods with Variable Step Size

    KAUST Repository

    Hadjimichael, Yiannis; Ketcheson, David I.; Loczi, Lajos; Né meth, Adriá n

    2016-01-01

    Strong stability preserving (SSP) methods are designed primarily for time integration of nonlinear hyperbolic PDEs, for which the permissible SSP step size varies from one step to the next. We develop the first SSP linear multistep methods (of order

  3. Pressure redistribution devices: what works, at what cost and what's next?

    Science.gov (United States)

    Clancy, Michael J

    2013-08-01

    This article discusses the development and usage of pressure redistribution devices (PRDs) and their impact on the prevention and treatment of pressure ulcers within the NHS. The article outlines the history of the development of these devices and discusses the reasons for a lack of substantial evidence in support of the use of these devices, their impact on the NHS on cost and perceived outcome. The article describes the typical usage profile in a 500 bed NHS hospital and concludes with a view as to how that may change in the future. Copyright © 2013 Tissue Viability Society. Published by Elsevier Ltd. All rights reserved.

  4. Resource management for device-to-device underlay communication

    CERN Document Server

    Song, Lingyang; Xu, Chen

    2013-01-01

    Device-to-Device (D2D) communication will become a key feature supported by next generation cellular networks, a topic of enormous importance to modern communication. Currently, D2D serves as an underlay to the cellular network as a means to increase spectral efficiency. Although D2D communication brings large benefits in terms of system capacity, it also causes interference as well as increased computation complexity to cellular networks as a result of spectrum sharing. Thus, efficient resource management must be performed to guarantee a target performance level of cellular communication.This

  5. Emerging technologies to measure neighborhood conditions in public health: implications for interventions and next steps.

    Science.gov (United States)

    Schootman, M; Nelson, E J; Werner, K; Shacham, E; Elliott, M; Ratnapradipa, K; Lian, M; McVay, A

    2016-06-23

    Adverse neighborhood conditions play an important role beyond individual characteristics. There is increasing interest in identifying specific characteristics of the social and built environments adversely affecting health outcomes. Most research has assessed aspects of such exposures via self-reported instruments or census data. Potential threats in the local environment may be subject to short-term changes that can only be measured with more nimble technology. The advent of new technologies may offer new opportunities to obtain geospatial data about neighborhoods that may circumvent the limitations of traditional data sources. This overview describes the utility, validity and reliability of selected emerging technologies to measure neighborhood conditions for public health applications. It also describes next steps for future research and opportunities for interventions. The paper presents an overview of the literature on measurement of the built and social environment in public health (Google Street View, webcams, crowdsourcing, remote sensing, social media, unmanned aerial vehicles, and lifespace) and location-based interventions. Emerging technologies such as Google Street View, social media, drones, webcams, and crowdsourcing may serve as effective and inexpensive tools to measure the ever-changing environment. Georeferenced social media responses may help identify where to target intervention activities, but also to passively evaluate their effectiveness. Future studies should measure exposure across key time points during the life-course as part of the exposome paradigm and integrate various types of data sources to measure environmental contexts. By harnessing these technologies, public health research can not only monitor populations and the environment, but intervene using novel strategies to improve the public health.

  6. Evidence-based practice, step by step: critical appraisal of the evidence: part II: digging deeper--examining the "keeper" studies.

    Science.gov (United States)

    Fineout-Overholt, Ellen; Melnyk, Bernadette Mazurek; Stillwell, Susan B; Williamson, Kathleen M

    2010-09-01

    This is the sixth article in a series from the Arizona State University College of Nursing and Health Innovation's Center for the Advancement of Evidence-Based Practice. Evidence-based practice (EBP) is a problem-solving approach to the delivery of health care that integrates the best evidence from studies and patient care data with clinician expertise and patient preferences and values. When delivered in a context of caring and in a supportive organizational culture, the highest quality of care and best patient outcomes can be achieved. The purpose of this series is to give nurses the knowledge and skills they need to implement EBP consistently, one step at a time. Articles will appear every two months to allow you time to incorporate information as you work toward implementing EBP at your institution. Also, we've scheduled "Chat with the Authors" calls every few months to provide a direct line to the experts to help you resolve questions. Details about how to participate in the next call will be published with November's Evidence-Based Practice, Step by Step.

  7. Global Monitoring Of Uranium Hexifloride Cylinders Next Steps In Development Of An Action Plan

    International Nuclear Information System (INIS)

    Hanks, D.

    2010-01-01

    Over 40 industrial facilities world-wide use standardized uranium hexafluoride (UF 6 ) cylinders for transport, storage and in-process receiving in support of uranium conversion, enrichment and fuel fabrication processes. UF 6 is processed and stored in the cylinders, with over 50,000 tU of UF 6 transported each year in these International Organization for Standardization (ISO) qualified containers. Although each cylinder is manufactured to an ISO standard that calls for a nameplate with the manufacturer's identification number (ID) and the owner's serial number engraved on it, these can be quite small and difficult to read. Recognizing that each facility seems to use a different ID, a cylinder can have several different numbers recorded on it by means of metal plates, sticky labels, paint or even marker pen as it travels among facilities around the world. The idea of monitoring movements of UF 6 cylinders throughout the global uranium fuel cycle has become a significant issue among industrial and safeguarding stakeholders. Global monitoring would provide the locations, movements, and uses of cylinders in commercial nuclear transport around the world, improving the efficiency of industrial operations while increasing the assurance that growing nuclear commerce does not result in the loss or misuse of cylinders. It should be noted that a unique ID (UID) attached to a cylinder in a verifiable manner is necessary for safeguarding needs and ensuring positive ID, but not sufficient for an effective global monitoring system. Modern technologies for tracking and inventory control can pair the UID with sensors and secure data storage for content information and complete continuity of knowledge over the cylinder. This paper will describe how the next steps in development of an action plan for employing a global UF 6 cylinder monitoring network could be cultivated using four primary UID functions - identification, tracking, controlling, and accounting.

  8. Creating a Content Strategy for Mobile Devices in the Classroom

    Science.gov (United States)

    Mahon, Karen

    2014-01-01

    Students' access to smartphones continues to grow. Use of tablets and e-readers continues to grow in the classroom. Whenever a large purchase of mobile devices is made for education, the very next question asked is, "Now what?" It is the planning for and using of the devices as part of an overall approach to the curriculum, locally, that…

  9. Mobile: Letting Go of the Device and Building for Innovation

    Science.gov (United States)

    Davis, Jim; Rocchio, Rosemary A.

    2011-01-01

    Mobile use of the Internet is on target to surpass fixed use by 2014. Three-fourths of all college/university students have purchased or intend to purchase an Internet-enabled handheld device within the next year. The smartphone market is changing almost monthly. Attempting to manage even just one or a few "devices" is becoming a lost…

  10. From supervision to resolution: next steps on the road to European banking union

    OpenAIRE

    Nicolas Véron; Guntram B. Wolff

    2013-01-01

    Listen to the press conference call. The European Council has outlined the creation of a Single Resolution Mechanism (SRM), complementing the Single Supervisory Mechanism. The thinking on the SRM’s legal basis, design and mission is still preliminary and depends on other major initiatives, including the European Stability Mechanism’s involvement in bank recapitalisations and the Bank Recovery and Resolution (BRR) Directive. The SRM should also not be seen as the final step creating Europe’s f...

  11. High-energy green supercapacitor driven by ionic liquid electrolytes as an ultra-high stable next-generation energy storage device

    Science.gov (United States)

    Thangavel, Ranjith; Kannan, Aravindaraj G.; Ponraj, Rubha; Thangavel, Vigneysh; Kim, Dong-Won; Lee, Yun-Sung

    2018-04-01

    Development of supercapacitors with high energy density and long cycle life using sustainable materials for next-generation applications is of paramount importance. The ongoing challenge is to elevate the energy density of supercapacitors on par with batteries, while upholding the power and cyclability. In addition, attaining such superior performance with green and sustainable bio-mass derived compounds is very crucial to address the rising environmental concerns. Herein, we demonstrate the use of watermelon rind, a bio-waste from watermelons, towards high energy, and ultra-stable high temperature green supercapacitors with a high-voltage ionic liquid electrolyte. Supercapacitors assembled with ultra-high surface area, hierarchically porous carbon exhibits a remarkable performance both at room temperature and at high temperature (60 °C) with maximum energy densities of ∼174 Wh kg-1 (25 °C), and 177 Wh kg-1 (60 °C) - based on active mass of both electrodes. Furthermore, an ultra-high specific power of ∼20 kW kg-1 along with an ultra-stable cycling performance with 90% retention over 150,000 cycles has been achieved even at 60 °C, outperforming supercapacitors assembled with other carbon based materials. These results demonstrate the potential to develop high-performing, green energy storage devices using eco-friendly materials for next generation electric vehicles and other advanced energy storage systems.

  12. Methods for growth of relatively large step-free SiC crystal surfaces

    Science.gov (United States)

    Neudeck, Philip G. (Inventor); Powell, J. Anthony (Inventor)

    2002-01-01

    A method for growing arrays of large-area device-size films of step-free (i.e., atomically flat) SiC surfaces for semiconductor electronic device applications is disclosed. This method utilizes a lateral growth process that better overcomes the effect of extended defects in the seed crystal substrate that limited the obtainable step-free area achievable by prior art processes. The step-free SiC surface is particularly suited for the heteroepitaxial growth of 3C (cubic) SiC, AlN, and GaN films used for the fabrication of both surface-sensitive devices (i.e., surface channel field effect transistors such as HEMT's and MOSFET's) as well as high-electric field devices (pn diodes and other solid-state power switching devices) that are sensitive to extended crystal defects.

  13. Trade studies of plasma elongation for next-step tokamaks

    International Nuclear Information System (INIS)

    Galambos, J.D.; Strickler, D.J.; Peng, Y.K.M.; Reid, R.L.

    1988-09-01

    The effect of elongation on minimum-cost devices is investigated for elongations ranging from 2 to 3. The analysis, carried out with the TETRA tokamak systems code, includes the effects of elongation on both physics (plasma beta limit) and engineering (poloidal field coil currents) issues. When ignition is required, the minimum cost occurs for elongations from 2.3 to 2.9, depending on the plasma energy confinement scaling used. Scalings that include favorable plasma current dependence and/or degradation with fusion power tend to have minimum cost at higher elongation (2.5-2.9); scalings that depend primarily on size result in lower elongation (/approximately/2.3) for minimum cost. For design concepts that include steady-state current-driven operation, minimum cost occurs at an elongation of 2.3. 12 refs., 13 figs

  14. ICRP 60 - the next step

    International Nuclear Information System (INIS)

    Harding, L.K.; Thomson, W.H.

    1993-01-01

    Following the publication in 1990 of the recommendations proposed by the International Commission on Radiological protection (ICRP 60), this editorial briefly highlights the advice given by the NRPB to UK government departments on how to implement those recommendations regarding occupational, medical and public exposure. (UK)

  15. A neuronal device for the control of multi-step computations

    OpenAIRE

    Zylberberg, Ariel D; Paz, Luciano; Roelfsema, Pieter R; Dehaene, Stanislas; Sigman, Mariano

    2013-01-01

    We describe the operation of a neuronal device which embodies the computational principles of the `paper-and-pencil' machine envisioned by Alan Turing. The network is based on principles of cortical organization. We develop a plausible solution to implement pointers and investigate how neuronal circuits may instantiate the basic operations involved in assigning a value to a variable (i.e., x=5), in determining whether two variables have the same value and in retrieving the value of a given va...

  16. Interactive Video, The Next Step

    Science.gov (United States)

    Strong, L. R.; Wold-Brennon, R.; Cooper, S. K.; Brinkhuis, D.

    2012-12-01

    Video has the ingredients to reach us emotionally - with amazing images, enthusiastic interviews, music, and video game-like animations-- and it's emotion that motivates us to learn more about our new interest. However, watching video is usually passive. New web-based technology is expanding and enhancing the video experience, creating opportunities to use video with more direct interaction. This talk will look at an Educaton and Outreach team's experience producing video-centric curriculum using innovative interactive media tools from TED-Ed and FlixMaster. The Consortium for Ocean Leadership's Deep Earth Academy has partnered with the Center for Dark Energy Biosphere Investigations (C-DEBI) to send educators and a video producer aboard three deep sea research expeditions to the Juan de Fuca plate to install and service sub-seafloor observatories. This collaboration between teachers, students, scientists and media producers has proved a productive confluence, providing new ways of understanding both ground-breaking science and the process of science itself - by experimenting with new ways to use multimedia during ocean-going expeditions and developing curriculum and other projects post-cruise.

  17. Present and next steps of the JAERI superconducting rf linac based FEL program

    International Nuclear Information System (INIS)

    Minehara, E.J.; Yamauchi, T.; Sugimoto, M.

    2000-01-01

    The JAERI superconducting rf linac based FEL has successfully been lased to produce a 0.3 kW FEL light and 100 kW or larger electron beam output in quasi continuous wave operation in 1999. The 1 kW class output as our present program goal will be achieved to improve the optical out coupling method in the FEL optical resonator, the electron gun, and the electron beam optics in the JAERI FEL driver. As our next 5 year program goal is the 100 kW class FEL light and a few tens MW class electron beam output in average, quasi continuous wave operation of the light and electron beam will be planned in the JAERI superconducting rf linac based FEL facility. Conceptual design options needed for such a very high power operation and shorter wavelength light sources will be discussed to improve and to upgrade the exciting facility. (author)

  18. REACH: next step to a sound chemicals management.

    Science.gov (United States)

    Van der Wielen, Arnold

    2007-12-01

    REACH is the new European Regulation for Registration, Evaluation, Authorisation and Restriction of Chemicals. It entered into force on 1st June 2007 to streamline and improve the former legislative framework on new and on existing chemical substances of the European Union. Companies which manufacture or import more than 1 tonne of a substance per year will be required to register the substance at the new EU Chemicals Agency located in Helsinki. REACH places greater responsibility on industry to manage the risks that chemicals may pose to the health and the environment and to provide safety information that will be passed down the supply chain. In principle, REACH applies to all chemicals as such, as components in preparations and as used in articles. REACH is a radical step forward in the EU chemicals management. The onus will move from the authorities to industry. In addition, REACH will allow the further evaluation of substances where there are grounds for concern, foresees an authorisation system for the use of substances of very high concern and a system of restrictions, where applicable, for substances of concern. The Authorisation system will require companies to switch progressively to safer alternatives where a suitable alternative exists. Current use restrictions will remain under REACH system.

  19. ADDING A NEW STEP WITH SPATIAL AUTOCORRELATION TO IMPROVE THE FOUR-STEP TRAVEL DEMAND MODEL WITH FEEDBACK FOR A DEVELOPING CITY

    Directory of Open Access Journals (Sweden)

    Xuesong FENG, Ph.D Candidate

    2009-01-01

    Full Text Available It is expected that improvement of transport networks could give rise to the change of spatial distributions of population-related factors and car ownership, which are expected to further influence travel demand. To properly reflect such an interdependence mechanism, an aggregate multinomial logit (A-MNL model was firstly applied to represent the spatial distributions of these exogenous variables of the travel demand model by reflecting the influence of transport networks. Next, the spatial autocorrelation analysis is introduced into the log-transformed A-MNL model (called SPA-MNL model. Thereafter, the SPA-MNL model is integrated into the four-step travel demand model with feedback (called 4-STEP model. As a result, an integrated travel demand model is newly developed and named as the SPA-STEP model. Using person trip data collected in Beijing, the performance of the SPA-STEP model is empirically compared with the 4-STEP model. It was proven that the SPA-STEP model is superior to the 4-STEP model in accuracy; most of the estimated parameters showed statistical differences in values. Moreover, though the results of the simulations to the same set of assumed scenarios by the 4-STEP model and the SPA-STEP model consistently suggested the same sustainable path for the future development of Beijing, it was found that the environmental sustainability and the traffic congestion for these scenarios were generally overestimated by the 4-STEP model compared with the corresponding analyses by the SPA-STEP model. Such differences were clearly generated by the introduction of the new modeling step with spatial autocorrelation.

  20. U.S. energy policy and next regulatory steps

    International Nuclear Information System (INIS)

    Pearce, D.

    2006-01-01

    This presentation examined energy policies taken in the past to develop to oil and gas activities in Alaska and examined regulatory steps that may be taken in the future. North Slope Alaska gas resources were also reviewed. The Alaska Natural Gas Transportation Act was passed in 1976, but the pipeline was not developed due to its high cost. The Alaska Natural Gas Pipeline Act was signed into law in 2004 along with a loan guarantee program and an alternate construction study. Tax bill provisions included accelerated depreciation for the pipeline as well as an enhanced oil recovery tax credit for a gas processing plant. A federal coordinator was selected to expedite reviews and actions, as well as to monitor responsibility in areas where the pipeline crosses Federal or private lands. Details of federal permitting agencies were also included. A summary of federal agency permits and approvals was provided along with details of a federal interdepartmental memorandum of understanding (MOU) and the responsibilities of the United States Department of Energy. The presentation also included outlines of technical risk management programs, support infrastructure needs, and an infrastructure upgrade study. Highway route options were discussed, as well as sites for facilities. tabs., figs

  1. Implementation of a variable-step integration technique for nonlinear structural dynamic analysis

    International Nuclear Information System (INIS)

    Underwood, P.; Park, K.C.

    1977-01-01

    The paper presents the implementation of a recently developed unconditionally stable implicit time integration method into a production computer code for the transient response analysis of nonlinear structural dynamic systems. The time integrator is packaged with two significant features; a variable step size that is automatically determined and this is accomplished without additional matrix refactorizations. The equations of motion solved by the time integrator must be cast in the pseudo-force form, and this provides the mechanism for controlling the step size. Step size control is accomplished by extrapolating the pseudo-force to the next time (the predicted pseudo-force), then performing the integration step and then recomputing the pseudo-force based on the current solution (the correct pseudo-force); from this data an error norm is constructed, the value of which determines the step size for the next step. To avoid refactoring the required matrix with each step size change a matrix scaling technique is employed, which allows step sizes to change by a factor of 100 without refactoring. If during a computer run the integrator determines it can run with a step size larger than 100 times the original minimum step size, the matrix is refactored to take advantage of the larger step size. The strategy for effecting these features are discussed in detail. (Auth.)

  2. Next-generation DNA sequencing of HEXA: a step in the right direction for carrier screening

    OpenAIRE

    Hoffman, Jodi D; Greger, Valerie; Strovel, Erin T; Blitzer, Miriam G; Umbarger, Mark A; Kennedy, Caleb; Bishop, Brian; Saunders, Patrick; Porreca, Gregory J; Schienda, Jaclyn; Davie, Jocelyn; Hallam, Stephanie; Towne, Charles

    2013-01-01

    Tay-Sachs disease (TSD) is the prototype for ethnic-based carrier screening, with a carrier rate of ∼1/27 in Ashkenazi Jews and French Canadians. HexA enzyme analysis is the current gold standard for TSD carrier screening (detection rate ∼98%), but has technical limitations. We compared DNA analysis by next-generation DNA sequencing (NGS) plus an assay for the 7.6 kb deletion to enzyme analysis for TSD carrier screening using 74 samples collected from participants at a TSD family conference. ...

  3. Rapid Stencil Mask Fabrication Enabled One-Step Polymer-Free Graphene Patterning and Direct Transfer for Flexible Graphene Devices.

    Science.gov (United States)

    Yong, Keong; Ashraf, Ali; Kang, Pilgyu; Nam, SungWoo

    2016-04-27

    We report a one-step polymer-free approach to patterning graphene using a stencil mask and oxygen plasma reactive-ion etching, with a subsequent polymer-free direct transfer for flexible graphene devices. Our stencil mask is fabricated via a subtractive, laser cutting manufacturing technique, followed by lamination of stencil mask onto graphene grown on Cu foil for patterning. Subsequently, micro-sized graphene features of various shapes are patterned via reactive-ion etching. The integrity of our graphene after patterning is confirmed by Raman spectroscopy. We further demonstrate the rapid prototyping capability of a stretchable, crumpled graphene strain sensor and patterned graphene condensation channels for potential applications in sensing and heat transfer, respectively. We further demonstrate that the polymer-free approach for both patterning and transfer to flexible substrates allows the realization of cleaner graphene features as confirmed by water contact angle measurements. We believe that our new method promotes rapid, facile fabrication of cleaner graphene devices, and can be extended to other two dimensional materials in the future.

  4. EDITORIAL: The next photonic revolution The next photonic revolution

    Science.gov (United States)

    Zheludev, Nikolay I.

    2009-11-01

    This special section on Nanophotonics and Metamaterials is a follow-up to the second European Topical Meeting of the NANOMETA series of meetings (see www.nanometa.org) which took place on 5-8 January 2009, in Seefeld, Austria. The main idea of the first NANOMETA meeting held in 2007 was to bring together the mature community of microwave electrical engineers with the emerging community of photonics researchers interested in the physics of light coupled to nanostructures. In recent years the research landscape has shifted dramatically. A wider proliferation of nanofabrication techniques such as electron beam lithography, nanoimprint and focused ion beam milling, diagnostics techniques such as near-field scanning imaging, cathodoluminescence with nanoscale resolution and micro-spectrometry, and the availability of affordable broadband and ultrafast optical sources, have moved the research focus of the NANOMETA community to the optical domain. Quite naturally the ideas of the nonlinearity of materials and the coherency of light in the nanoscale realm have been widely discussed. Driven by the dream of untapped device and material functionality, nonlinear and switchable nanophotonic devices and photonic metamaterials, along with the concept of tailoring the electromagnetic space with metamaterials, appear to be the main avenues along which the subject will develop in the coming years. Indeed, in the last 20 years photonics has played a key role in creating the world as we know it, with enormous beneficial social impact worldwide. It is impossible to imagine modern society without the globe-spanning broadband internet and mobile telephony made possible by the implementation of optical fibre core networks, optical disc data storage (underpinned by the development of compact semiconductor lasers), modern image display technologies and laser-assisted manufacturing. We now anticipate that the next photonic revolution will continue to grow, explosively fuelled by a new

  5. WE-E-18A-08: Towards a Next-Generation Electronic Portal Device for Simultaneous Imaging and Dose Verification in Radiotherapy

    International Nuclear Information System (INIS)

    Blake, S; Vial, P; Holloway, L; Kuncic, Z

    2014-01-01

    Purpose: This work forms part of an ongoing study to develop a next-generation electronic portal imaging device (EPID) for simultaneous imaging and dose verification in radiotherapy. Monte Carlo (MC) simulations were used to characterize the imaging performance of a novel EPID that has previously been demonstrated to exhibit a water-equivalent response. The EPID ' s response was quantified in several configurations and model parameters were empirically validated against experimental measurements. Methods: A MC model of a novel a-Si EPID incorporating an array of plastic scintillating fibers was developed. Square BCF-99-06A scintillator fibers with PMMA cladding (Saint-Gobain Crystals) were modelled in a matrix with total area measuring 150×150 mm 2 . The standard electromagnetic and optical physics Geant4 classes were used to simulate radiation transport from an angled slit source (6 MV energy spectrum) through the EPID and optical photons reaching the photodiodes were scored. The prototype's modulation transfer function (MTF) was simulated and validated against experimental measurements. Several optical transport parameters, fiber lengths and thicknesses of an air gap between the scintillator and photodiodes were investigated to quantify their effects on the prototype's detection efficiency, sensitivity and MTF. Results: Simulated EPID response was more sensitive to variations in geometry than in the optical parameters studied. The MTF was particularly sensitive to the introduction of a 0.5–1.0 mm air gap between the scintillator and photodiodes, which lowered the MTF relative to that simulated without the gap. As expected, increasing the fiber length increased the detector efficiency and sensitivity while decreasing the MTF. Conclusion: A model of a novel water-equivalent EPID has been developed and benchmarked against measurements using a physical prototype. We have demonstrated the feasibility of this new device and are continuing to optimize

  6. Next to leading order three jet production at hadron colliders

    International Nuclear Information System (INIS)

    Kilgore, W.

    1997-01-01

    Results from a next-to-leading order event generator of purely gluonic jet production are presented. This calculation is the first step in the construction of a full next-to-leading order calculation of three jet production at hadron colliders. Several jet algorithms commonly used in experiments are implemented and their numerical stability is investigated. A numerical instability is found in the iterative cone algorithm which makes it inappropriate for use in fixed order calculations beyond leading order. (author)

  7. Reactor power control device in BWR power plant

    International Nuclear Information System (INIS)

    Kurosawa, Tsuneo.

    1997-01-01

    The present invention provides a device for controlling reactor power based on a start-up/shut down program in a BWR type reactor, as well as for detecting deviation, if occurs, of the power from the start-up/shut down program, to control a recycling flow rate control system or control rod drive mechanisms. Namely, a power instruction section successively executes the start-up/shut down program and controls the coolant recycling system and the control rod driving mechanisms to control the power. A current state monitoring and calculation section receives a process amount, calculates parameters showing the plant state, compares/monitors them with predetermined values, detecting the deviation, if occurs, of the plant state from the start-up/shut down program, and prevents output of a power increase control signal which leads to power increase. A forecasting and monitoring/calculation section forecasts and calculates the plant state when not yet executed steps of the start-up/shut down program are performed, stops the execution of the start-up/shut down program in the next step in a case of forecasting that the results of the calculation will deviate from the start-up/shut down program. (I.S.)

  8. Corporate restructuring of the global energy industry, the next steps: the case of gas in Europe

    International Nuclear Information System (INIS)

    Roland, K.; Soerensen, E.S.

    2000-01-01

    The European energy sector will undergo a wave of restructuring and reorganization in the next 12 to 36 months. Deregulation at both the EU and national levels provides a catalyst, creating a range of new commercial forces that will require actors fundamentally to reappraise their business strategies. Companies will look for efficiency gains, economies of scale and scope, new approaches to risk management and a strategic positioning in the pan-European market. This will result in far-reaching structural changes in the industry, leading to a small number of large, vertically integrated energy companies with a wide spread of geographical interests. In this paper, we analyse these trends with reference to the European gas industry. (orig.)

  9. Critical flux determination by flux-stepping

    DEFF Research Database (Denmark)

    Beier, Søren; Jonsson, Gunnar Eigil

    2010-01-01

    In membrane filtration related scientific literature, often step-by-step determined critical fluxes are reported. Using a dynamic microfiltration device, it is shown that critical fluxes determined from two different flux-stepping methods are dependent upon operational parameters such as step...... length, step height, and.flux start level. Filtrating 8 kg/m(3) yeast cell suspensions by a vibrating 0.45 x 10(-6) m pore size microfiltration hollow fiber module, critical fluxes from 5.6 x 10(-6) to 1.2 x 10(-5) m/s have been measured using various step lengths from 300 to 1200 seconds. Thus......, such values are more or less useless in itself as critical flux predictors, and constant flux verification experiments have to be conducted to check if the determined critical fluxes call predict sustainable flux regimes. However, it is shown that using the step-by-step predicted critical fluxes as start...

  10. Can use of walkers or canes impede lateral compensatory stepping movements?

    Science.gov (United States)

    Bateni, Hamid; Heung, Evelyn; Zettel, John; McLlroy, William E; Maki, Brian E

    2004-08-01

    Although assistive devices, such as walkers and canes are often prescribed to aid in balance control, recent studies have suggested that such devices may actually increase risk of falling. In this study, we investigated one possible mechanism: the potential for walkers or canes to interfere with, or constrain, lateral movement of the feet and thereby impede execution of compensatory stepping reactions during lateral loss of balance. Lateral stepping reactions were evoked, in 10 healthy young adults (ages 22-27 years), by means of sudden unpredictable medio-lateral support surface translation. Subjects were tested while holding and loading a standard pickup walker or single-tip cane or while using no assistive device (hands free or holding an object). Results supported the hypothesis that using a walker or cane can interfere with compensatory stepping. Collisions between the swing-foot and mobility aid were remarkably frequent when using the walker (60% of stepping reactions) and also occurred in cane trials (11% of stepping reactions). Furthermore, such collisions were associated with a significant reduction (26-37%) in lateral step length. It appeared that subjects were sometimes able to avoid collision by increasing the forward or backward displacement of the swing-foot or by moving the cane; however, attempts to lift the walker out of the way occurred rarely and were usually impeded due to collision between the contralateral walker post and stance foot. The fact that compensatory stepping behavior was altered significantly in such a healthy cohort clearly demonstrates some of the safety limitations inherent to these assistive devices, as currently designed. Copyright 2003 Elsevier B.V.

  11. Quantum dot optoelectronic devices: lasers, photodetectors and solar cells

    International Nuclear Information System (INIS)

    Wu, Jiang; Chen, Siming; Seeds, Alwyn; Liu, Huiyun

    2015-01-01

    Nanometre-scale semiconductor devices have been envisioned as next-generation technologies with high integration and functionality. Quantum dots, or the so-called ‘artificial atoms’, exhibit unique properties due to their quantum confinement in all 3D. These unique properties have brought to light the great potential of quantum dots in optoelectronic applications. Numerous efforts worldwide have been devoted to these promising nanomaterials for next-generation optoelectronic devices, such as lasers, photodetectors, amplifiers, and solar cells, with the emphasis on improving performance and functionality. Through the development in optoelectronic devices based on quantum dots over the last two decades, quantum dot devices with exceptional performance surpassing previous devices are evidenced. This review describes recent developments in quantum dot optoelectronic devices over the last few years. The paper will highlight the major progress made in 1.3 μm quantum dot lasers, quantum dot infrared photodetectors, and quantum dot solar cells. (topical review)

  12. Tracking Steps on Apple Watch at Different Walking Speeds.

    Science.gov (United States)

    Veerabhadrappa, Praveen; Moran, Matthew Duffy; Renninger, Mitchell D; Rhudy, Matthew B; Dreisbach, Scott B; Gift, Kristin M

    2018-04-09

    QUESTION: How accurate are the step counts obtained from Apple Watch? In this validation study, video steps vs. Apple Watch steps (mean ± SD) were 2965 ± 144 vs. 2964 ± 145 steps; P Apple Watch steps when compared with the manual counts obtained from video recordings. Our study is one of the initial studies to objectively validate the accuracy of the step counts obtained from Apple watch at different walking speeds. Apple Watch tested to be an extremely accurate device for measuring daily step counts for adults.

  13. Direct Taxation in the Eu: The Common Corporate Tax Base as the Next Sub-Step towards Harmonization

    Directory of Open Access Journals (Sweden)

    Norbert Herzig

    2011-12-01

    Full Text Available This paper analyzes the Common Corporate Tax Base (CCTB as an interim alternative to the proposal of a Council directive on a Common Consolidated Corporate Tax Base (CCCTB. The CCCTB concept does not only include common rules for determining the tax base like the CCTB but also the steps of consolidation and subsequent formula apportionment. Therefore, the paper starts by showing that particularly these second and third steps of the CCCTB project meet fierce political opposition from several Member States and do leave leeway for tax planning. Afterwards, the CCCTB proposal's approach to common rules for determining the tax base is evaluated, i.e. tested for its suitability as a point of departure for drafting a CCTB. Finally, various other aspects of the proposal are examined in light of a CCTB without consolidation.

  14. GLOBAL MONITORING OF URANIUM HEXIFLORIDE CYLINDERS NEXT STEPS IN DEVELOPMENT OF AN ACTION PLAN

    Energy Technology Data Exchange (ETDEWEB)

    Hanks, D.

    2010-06-09

    Over 40 industrial facilities world-wide use standardized uranium hexafluoride (UF{sub 6}) cylinders for transport, storage and in-process receiving in support of uranium conversion, enrichment and fuel fabrication processes. UF{sub 6} is processed and stored in the cylinders, with over 50,000 tU of UF{sub 6} transported each year in these International Organization for Standardization (ISO) qualified containers. Although each cylinder is manufactured to an ISO standard that calls for a nameplate with the manufacturer's identification number (ID) and the owner's serial number engraved on it, these can be quite small and difficult to read. Recognizing that each facility seems to use a different ID, a cylinder can have several different numbers recorded on it by means of metal plates, sticky labels, paint or even marker pen as it travels among facilities around the world. The idea of monitoring movements of UF{sub 6} cylinders throughout the global uranium fuel cycle has become a significant issue among industrial and safeguarding stakeholders. Global monitoring would provide the locations, movements, and uses of cylinders in commercial nuclear transport around the world, improving the efficiency of industrial operations while increasing the assurance that growing nuclear commerce does not result in the loss or misuse of cylinders. It should be noted that a unique ID (UID) attached to a cylinder in a verifiable manner is necessary for safeguarding needs and ensuring positive ID, but not sufficient for an effective global monitoring system. Modern technologies for tracking and inventory control can pair the UID with sensors and secure data storage for content information and complete continuity of knowledge over the cylinder. This paper will describe how the next steps in development of an action plan for employing a global UF{sub 6} cylinder monitoring network could be cultivated using four primary UID functions - identification, tracking, controlling, and

  15. Colloidal Quantum Dot Inks for Single-Step-Fabricated Field-Effect Transistors: The Importance of Postdeposition Ligand Removal.

    Science.gov (United States)

    Balazs, Daniel M; Rizkia, Nisrina; Fang, Hong-Hua; Dirin, Dmitry N; Momand, Jamo; Kooi, Bart J; Kovalenko, Maksym V; Loi, Maria Antonietta

    2018-02-14

    Colloidal quantum dots are a class of solution-processed semiconductors with good prospects for photovoltaic and optoelectronic applications. Removal of the surfactant, so-called ligand exchange, is a crucial step in making the solid films conductive, but performing it in solid state introduces surface defects and cracks in the films. Hence, the formation of thick, device-grade films have only been possible through layer-by-layer processing, limiting the technological interest for quantum dot solids. Solution-phase ligand exchange before the deposition allows for the direct deposition of thick, homogeneous films suitable for device applications. In this work, fabrication of field-effect transistors in a single step is reported using blade-coating, an upscalable, industrially relevant technique. Most importantly, a postdeposition washing step results in device properties comparable to the best layer-by-layer processed devices, opening the way for large-scale fabrication and further interest from the research community.

  16. The future of the pharmaceutical, biological and medical device industry

    Directory of Open Access Journals (Sweden)

    Burgess LJ

    2011-09-01

    Full Text Available Lesley J Burgess, Marli TerblancheTREAD Research/Cardiology Unit, Department of Internal Medicine, Tygerberg Hospital and University of Stellenbosch, Parow, South AfricaAbstract: Numerous factors contribute to the declining pharmaceutical industry on the one hand and the rapidly growing generic industry together with the growing importance of medical devices and biologicals on the other. It is clear that the pharmaceutical industry is going to undergo a change in the next decade in order to meet the current challenges facing it and ultimately sustain its profitability and growth. This paper aims to identify a number of fairly obvious trends that are likely to have a significant impact on the product development pipeline in the next decade. It is more than clear that the current production pipeline for pharmaceutical, biotechnology and medical device industries is no longer sustainable and that urgent interventions are required in order to maintain its current level of profitability.Keywords: pharmaceutical industry, personalized medicine, trends, generics, biotechnology

  17. Technology for the Next-Generation-Mobile User Experience

    Science.gov (United States)

    Delagi, Greg

    The current mobile-handset market is a vital and growing one, being driven by technology advances, including increased bandwidth and processing performance, as well as reduced power consumption and improved screen technologies. The 3G/4G handsets of today are multimedia internet devices with increased screen size, HD video and gaming, interactive touch screens, HD camera and camcorders, as well as incredible social, entertainment, and productivity applications. While mobile-technology advancements to date have made us more social in many ways, new advancements over the next decade will bring us to the next level, allowing mobile users to experience new types of "virtual" social interactions with all the senses. The mobile handsets of the future will be smart autonomous-lifestyle devices with a multitude of incorporated sensors, applications and display options, all designed to make your life easier and more productive! With future display media, including 3D imaging, virtual interaction and conferencing will be possible, making every call feel like you are in the same room, providing an experience far beyond today's video conferencing technology. 3D touch-screen with integrated image-projection technologies will work in conjunction with gesturing to bring a new era of intuitive mobile device applications, interaction, and information sharing. Looking to the future, there are many challenges to be faced in delivering a smart mobile companion device that will meet the user demands. One demand will be for the availability of new and compelling services, and features on the "mobile companion". These mobile companions will be more than just Internet devices, and will function as on-the-go workstations, allowing users to function as if they were sitting in front of their computer in the office or at home. The massive amounts of data that will be transmitted through, to and from these mobile companions will require immense improvements in system performance, including

  18. Technology 2.0: A Commentary on Progress, Challenges, and Next Steps.

    Science.gov (United States)

    Jones, Deborah J

    2017-11-01

    This commentary highlights the importance and promise of the innovative strategies described in the Child Maltreatment special issue on "Technology 2.0: A Focus on the Newest Technological Advances in Child Maltreatment Research." The commentary first highlights the collective advancements reflected in the articles in the special issue, with a primary focus on how the authors' work addresses a general challenge in services research that is perhaps nowhere more problematic than in the field of maltreatment. Next, the commentary extends the discussion of these articles to raise remaining gaps in our knowledge, theory, and methodology, which must be the focus of ongoing research if the true potential of technology as a service delivery vehicle is to be realized. Finally, the commentary concludes with a call for subsequent research which will be inspired by the articles in this special issue.

  19. Rooting an Android Device

    Science.gov (United States)

    2015-09-01

    1. Overview The purpose of this document is to demonstrate how to gain administrative privileges on an Android device. The term “rooting” is...is applicable for the Samsung Galaxy S3 as well as many other Android devices, but there are several steps involved in rooting an Android device (as...root access has been granted. 4. Conclusion This document serves as a tutorial on how to grant user administrative privilege to an Android device by

  20. The Next Step in Understanding Impaired Reactive Balance Control in People With Stroke: The Role of Defective Early Automatic Postural Responses.

    Science.gov (United States)

    de Kam, Digna; Roelofs, Jolanda M B; Bruijnes, Amber K B D; Geurts, Alexander C H; Weerdesteyn, Vivian

    2017-08-01

    Postural muscle responses are often impaired after stroke. We aimed to identify the contribution of deficits in very early postural responses to poorer reactive balance capacity, with a particular focus on reactive stepping as a key strategy for avoiding falls. A total of 34 chronic stroke survivors and 17 controls were subjected to translational balance perturbations in 4 directions. We identified the highest perturbation intensity that could be recovered without stepping (single stepping threshold [SST]) and with maximally 1 step (multiple stepping threshold [MST]). We determined onset latencies and response amplitudes of 7 leg muscles bilaterally and identified associations with balance capacity. People with stroke had a lower MST than controls in all directions. Side steps resulted in a higher lateral MST than crossover steps but were less common toward the paretic side. Postural responses were delayed and smaller in amplitude on the paretic side only. We observed the strongest associations between gluteus medius (GLUT) onset and amplitude and MST toward the paretic side ( R 2 = 0.33). Electromyographic variables were rather weakly associated with forward and backward MSTs ( R 2 = 0.10-0.22) and with SSTs ( R 2 = 0.08-0.15). Delayed and reduced paretic postural responses are associated with impaired reactive stepping after stroke. Particularly, fast and vigorous activity of the GLUT is imperative for overcoming large sideways perturbations, presumably because it facilitates the effective use of side steps. Because people with stroke often fall toward the paretic side, this finding indicates an important target for training.

  1. [Design of SCM inoculation device].

    Science.gov (United States)

    Qian, Mingli; Xie, Haiyuan

    2014-01-01

    The first step of bacilli culture is inoculation bacteria on culture medium. Designing a device to increase efficiency of inoculation is significative. The new device is controlled by SCM. The stepper motor can drive the culture medium rotating, accelerating, decelerating, overturn and suspending. The device is high practicability and efficient, let inoculation easy for operator.

  2. Fibre Optic Communication Key Devices

    CERN Document Server

    Grote, Norbert

    2012-01-01

    The book gives an in-depth description of the key devices of current and next generation fibre optic communication networks. In particular, the book covers devices such as semiconductor lasers, optical amplifiers, modulators, wavelength filters, and detectors but the relevant properties of optical fibres as well. The presentations include the physical principles underlying the various devices, the technologies used for the realization of the different devices, typical performance characteristics and limitations, and development trends towards more advanced components are also illustrated. Thus the scope of the book spans relevant principles, state-of-the-art implementations, the status of current research and expected future components.

  3. Estabilishing requirements for the next generation of pressurized water reactors--reducing the uncertainty

    International Nuclear Information System (INIS)

    Chernock, W.P.; Corcoran, W.R.; Rasin, W.H.; Stahlkopf, K.E.

    1987-01-01

    The Electric Power Research Institute is managing a major effort to establish requirements for the next generation of U.S. light water reactors. This effort is the vital first step in preserving the viability of the nuclear option to contribute to meet U.S. national electric power capacity needs in the next century. Combustion Engineering, Inc. and Duke Power Company formed a team to participate in the EPRI program which is guided by a Utility Steering committee consisting of experienced utility technical executives. A major thrust of the program is to reduce the uncertainties which would be faced by the utility executives in choosing the nuclear option. The uncertainties to be reduced include those related to safety, economic, operational, and regulatory aspects of advanced light water reactors. This paper overviews the Requirements Document program as it relates to the U.S. Advanced Light Water Reactor (ALWR) effort in reducing these uncertainties and reports the status of efforts to establish requirements for the next generation of pressurized water reactors. It concentrates on progress made in reducing the uncertainties which would deter selection of the nuclear option for contributing to U.S. national electric power capacity needs in the next century and updates previous reports in the same area. (author)

  4. Design evolution enhances patient compliance for low-intensity pulsed ultrasound device usage

    Directory of Open Access Journals (Sweden)

    Pounder NM

    2016-11-01

    Full Text Available Neill M Pounder, John T Jones, Kevin J Tanis Bioventus LLC, Durham, NC, USA Abstract: Poor patient compliance or nonadherence with prescribed treatments can have a significant unfavorable impact on medical costs and clinical outcomes. In the current study, voice-of-the-customer research was conducted to aid in the development of a next-generation low-intensity pulsed ultrasound (LIPUS bone healing product. An opportunity to improve patient compliance reporting was identified, resulting in the incorporation into the next-generation device of a visual calendar that provides direct feedback to the patient, indicating days for which they successfully completed treatment. Further ­investigation was done on whether inclusion of the visual calendar improved patient adherence to the prescribed therapy (20 minutes of daily treatment over a 6-month period. Thus, 12,984 data files were analyzed from patients prescribed either the earlier- or the next-generation LIPUS device. Over the 6-month period, overall patient compliance was 83.8% with the next-generation LIPUS device, compared with 74.2% for the previous version (p<0.0001. Incorporation of the calendar feature resulted in compliance never decreasing below 76% over the analysis period, whereas compliance with the earlier-generation product fell to 51%. A literature review on the LIPUS device shows a correlation between clinical effectiveness and compliance rates more than 70%. Incorporation of stakeholder feedback throughout the design and innovation process of a next-generation LIPUS device resulted in a measurable improvement in patient adherence, which may help to optimize clinical outcomes. Keywords: LIPUS, ultrasound, compliance, patient adherence, medical device design

  5. Device for controlling gas recovery

    International Nuclear Information System (INIS)

    Ichioka, Atsushi.

    1976-01-01

    Purpose: To provide a controlling device for UF 6 gas recovery device, which can increase working efficiency and to discriminate normality and abnormality of the recovery device. Constitution: The gas recovery device comprises a plurality of traps, which are connected in series. The UF 6 gas is introduced into the first trap where adsorbing work is taken place to accumulate UF 6 gases, and the UF 6 gases partly flow into the succeeding trap. Even in this trap, when the adsorbing work begins, the succeeding trap is operated in series fashion. In this manner, two traps are continuously operated to recover the gases while performing the steps of adsorbing, waiting and regenerating in that order. The switching operation of the aforesaid steps is accomplished on the basis of concentration of the UF 6 detected between two traps, which are continuously driven. (Kamimura, M.)

  6. A Survey on 5G: The Next Generation of Mobile Communication

    OpenAIRE

    Panwar, Nisha; Sharma, Shantanu; Singh, Awadhesh Kumar

    2015-01-01

    The rapidly increasing number of mobile devices, voluminous data, and higher data rate are pushing to rethink the current generation of the cellular mobile communication. The next or fifth generation (5G) cellular networks are expected to meet high-end requirements. The 5G networks are broadly characterized by three unique features: ubiquitous connectivity, extremely low latency, and very high-speed data transfer. The 5G networks would provide novel architectures and technologies beyond state...

  7. Medical device registration, agreements on mutual recognition - a step forward to global harmonization?

    International Nuclear Information System (INIS)

    Eidenberger, R.Reiner

    2000-01-01

    The purpose of this article is to give a short overview of some different regulations in Europe and the United States with regard to the clearance of medical devices and to give an outlook of what the Agreements on Mutual Recognition will bring in terms of Global Harmonization. Recent European legislation, the Council Directive 93/42/EEC of 14 June 1993 concerning medical devices (Medical Device Directive, MDD), requires that all medical devices placed on the European market bear the CE marking. From 14 June 1998, medical devices fall under the scope of this European Medical Device Directive and there is a harmonization within the European market. Similar to this, but for another market, are the USA FDA requirements, Premarket Approval (PMA) and Premarket notification (510(k)). The same medical device, the same goal - a safe product - but different legislation and thus duplication of registration procedures. The European Commission is presently discussing a series of agreements with third countries, Australia, New Zealand, USA, Canada, Japan and Eastern European countries wishing to join the EU, concerning the mutual acceptance of inspection bodies and, ultimately, proof of conformity (for example reports on examination, certificates, licenses and marks of conformity) in connection with medical devices. Meanwhile agreements with Australia, New Zealand, USA and Canada came into force. (author)

  8. Next Generation of Photovoltaics New Concepts

    CERN Document Server

    Vega, Antonio; López, Antonio

    2012-01-01

    This book presents new concepts for a next generation of PV. Among these concepts are: Multijunction solar cells, multiple excitation solar cells (or how to take benefit of high energy photons for the creation of more than one electron hole-pair), intermediate band solar cells (or how to take advantage of below band-gap energy photons) and related technologies (for quantum dots, nitrides, thin films), advanced light management approaches (plasmonics). Written by world-class experts in next generation photovoltaics this book is an essential reference guide accessible to both beginners and experts working with solar cell technology. The book deeply analyzes the current state-of-the-art of the new photovoltaic approaches and outlines the implementation paths of these advanced devices. Topics addressed range from the fundamentals to the description of state-of-the-art of the new types of solar cells.

  9. Next generation of photovoltaics. New concepts

    Energy Technology Data Exchange (ETDEWEB)

    Cristobal Lopez, Ana Belen; Marti Vega, Antonio; Luque Lopez, Antonio (eds.) [Univ. Politecnica de Madrid (Spain). Inst. de Energia Solar E.T.S.I. Telecomunicacion

    2012-07-01

    This book presents new concepts for a next generation of PV. Among these concepts are: Multijunction solar cells, multiple excitation solar cells (or how to take benefit of high energy photons for the creation of more than one electron hole-pair), intermediate band solar cells (or how to take advantage of below band-gap energy photons) and related technologies (for quantum dots, nitrides, thin films), advanced light management approaches (plasmonics). Written by world-class experts in next generation photovoltaics this book is an essential reference guide accessible to both beginners and experts working with solar cell technology. The book deeply analyzes the current state-of-the-art of the new photovoltaic approaches and outlines the implementation paths of these advanced devices. Topics addressed range from the fundamentals to the description of state-of-the-art of the new types of solar cells. (orig.)

  10. Next generation sensors and systems

    CERN Document Server

    2016-01-01

    Written by experts in their area of research, this book has outlined the current status of the fundamentals and analytical concepts, modelling and design issues, technical details and practical applications of different types of sensors and discussed about the trends of next generation of sensors and systems happening in the area of Sensing technology. This book will be useful as a reference book for engineers and scientist especially the post-graduate students find will this book as reference book for their research on wearable sensors, devices and technologies.  .

  11. Assistive devices alter gait patterns in Parkinson disease: advantages of the four-wheeled walker.

    Science.gov (United States)

    Kegelmeyer, Deb A; Parthasarathy, Sowmya; Kostyk, Sandra K; White, Susan E; Kloos, Anne D

    2013-05-01

    Gait abnormalities are a hallmark of Parkinson's disease (PD) and contribute to fall risk. Therapy and exercise are often encouraged to increase mobility and decrease falls. As disease symptoms progress, assistive devices are often prescribed. There are no guidelines for choosing appropriate ambulatory devices. This unique study systematically examined the impact of a broad range of assistive devices on gait measures during walking in both a straight path and around obstacles in individuals with PD. Quantitative gait measures, including velocity, stride length, percent swing and double support time, and coefficients of variation were assessed in 27 individuals with PD with or without one of six different devices including canes, standard and wheeled walkers (two, four or U-Step). Data were collected using the GAITRite and on a figure-of-eight course. All devices, with the exception of four-wheeled and U-Step walkers significantly decreased gait velocity. The four-wheeled walker resulted in less variability in gait measures and had less impact on spontaneous unassisted gait patterns. The U-Step walker exhibited the highest variability across all parameters followed by the two-wheeled and standard walkers. Higher variability has been correlated with increased falls. Though subjects performed better on a figure-of-eight course using either the four-wheeled or the U-Step walker, the four-wheeled walker resulted in the most consistent improvement in overall gait variables. Laser light use on a U-Step walker did not improve gait measures or safety in figure-of-eight compared to other devices. Of the devices tested, the four-wheeled-walker offered the most consistent advantages for improving mobility and safety. Copyright © 2012 Elsevier B.V. All rights reserved.

  12. Two-Dimensional Metal Oxide Nanomaterials for Next-Generation Rechargeable Batteries.

    Science.gov (United States)

    Mei, Jun; Liao, Ting; Kou, Liangzhi; Sun, Ziqi

    2017-12-01

    The exponential increase in research focused on two-dimensional (2D) metal oxides has offered an unprecedented opportunity for their use in energy conversion and storage devices, especially for promising next-generation rechargeable batteries, such as lithium-ion batteries (LIBs) and sodium-ion batteries (NIBs), as well as some post-lithium batteries, including lithium-sulfur batteries, lithium-air batteries, etc. The introduction of well-designed 2D metal oxide nanomaterials into next-generation rechargeable batteries has significantly enhanced the performance of these energy-storage devices by providing higher chemically active interfaces, shortened ion-diffusion lengths, and improved in-plane carrier-/charge-transport kinetics, which have greatly promoted the development of nanotechnology and the practical application of rechargeable batteries. Here, the recent progress in the application of 2D metal oxide nanomaterials in a series of rechargeable LIBs, NIBs, and other post lithium-ion batteries is reviewed relatively comprehensively. Current opportunities and future challenges for the application of 2D nanomaterials in energy-storage devices to achieve high energy density, high power density, stable cyclability, etc. are summarized and outlined. It is believed that the integration of 2D metal oxide nanomaterials in these clean energy devices offers great opportunities to address challenges driven by increasing global energy demands. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Step-Up DC-DC converters

    DEFF Research Database (Denmark)

    Forouzesh, Mojtaba; Siwakoti, Yam P.; Gorji, Saman A.

    2017-01-01

    on the general law and framework of the development of next-generation step-up dc-dc converters, this paper aims to comprehensively review and classify various step-up dc-dc converters based on their characteristics and voltage-boosting techniques. In addition, the advantages and disadvantages of these voltage......DC-DC converters with voltage boost capability are widely used in a large number of power conversion applications, from fraction-of-volt to tens of thousands of volts at power levels from milliwatts to megawatts. The literature has reported on various voltage-boosting techniques, in which......-boosting techniques and associated converters are discussed in detail. Finally, broad applications of dc-dc converters are presented and summarized with comparative study of different voltage-boosting techniques....

  14. The Role of a Mental Model in Learning to Operate a Device.

    Science.gov (United States)

    Kieras, David E.; Bovair, Susan

    1984-01-01

    Describes three studies concerned with learning to operate a control panel device and how this learning is affected by understanding a device model that describes its internal mechanism. Results indicate benefits of a device model depend on whether it supports direct inference of exact steps required to operate the device. (Author/MBR)

  15. Improved Full-Newton Step O(nL) Infeasible Interior-Point Method for Linear Optimization

    OpenAIRE

    Gu, G.; Mansouri, H.; Zangiabadi, M.; Bai, Y.Q.; Roos, C.

    2009-01-01

    We present several improvements of the full-Newton step infeasible interior-point method for linear optimization introduced by Roos (SIAM J. Optim. 16(4):1110–1136, 2006). Each main step of the method consists of a feasibility step and several centering steps. We use a more natural feasibility step, which targets the ?+-center of the next pair of perturbed problems. As for the centering steps, we apply a sharper quadratic convergence result, which leads to a slightly wider neighborhood for th...

  16. International Conference on NextGen Electronic Technologies

    CERN Document Server

    Thalmann, Nadia; Bhaaskaran, V

    2017-01-01

    This book is a collection of keynote lectures from international experts presented at International Conference on NextGen Electronic Technologies (ICNETS2-2016). ICNETS2 encompasses six symposia covering all aspects of electronics and communications domains, including relevant nano/micro materials and devices . This volume comprises of recent research in areas like computational signal processing analysis, intelligent embedded systems, nanoelectronic materials and devices, optical and microwave technologies, VLSI design: circuits systems and application, and wireless communication networks, and the internet of things. The contents of this book will be useful to researchers, professionals, and students working in the core areas of electronics and their applications, especially to signal processing, embedded systems, and networking.

  17. Performance enhancement of a heterojunction bipolar transistor (HBT) by two-step passivation

    International Nuclear Information System (INIS)

    Fu, S.-I.; Lai, P.-H.; Tsai, Y.-Y.; Hung, C.-W.; Yen, C.-H.; Cheng, S.-Y.; Liu, W.-C.

    2006-01-01

    An interesting two-step passivation (with ledge structure and sulphide based chemical treatment) on base surface, for the first time, is demonstrated to study the temperature-dependent DC characteristics and noise performance of an InGaP/GaAs heterojunction bipolar transistor (HBT). Improved transistor behaviors on maximum current gain β max , offset voltage ΔV CE , and emitter size effect are obtained by using the two-step passivation. Moreover, the device with the two-step passivation exhibits relatively temperature-independent and improved thermal stable performances as the temperature is increased. Therefore, the two-step passivationed device can be used for high-temperature and low-power electronics applications

  18. Mobile location services over the next generation IP core network

    DEFF Research Database (Denmark)

    Thongthammachart, Saowanee; Olesen, Henning

    2003-01-01

    network is changing from circuit-switched to packet-switched technology and evolving to an IP core network based on IPv6. The IP core network will allow all IP devices to be connected seamlessly. Due to the movement detection mechanism of Mobile IPv6, mobile terminals will periodically update....... The concept of mobile location services over the next generation IP networks is described. We also discuss the effectiveness of the short-range wireless network regarding a mobile user's position inside buildings and hotspot areas....

  19. SYSTEMATIZATION OF THE BASIC STEPS OF THE STEP-AEROBICS

    Directory of Open Access Journals (Sweden)

    Darinka Korovljev

    2011-03-01

    Full Text Available Following the development of the powerful sport industry, in front of us appeared a lot of new opportunities for creating of the new programmes of exercising with certain requisites. One of such programmes is certainly step-aerobics. Step-aerobics can be defined as a type of aerobics consisting of the basic aerobic steps (basic steps applied in exercising on stepper (step bench, with a possibility to regulate its height. Step-aerobics itself can be divided into several groups, depending on the following: type of music, working methods and adopted knowledge of the attendants. In this work, the systematization of the basic steps in step-aerobics was made on the basis of the following criteria: steps origin, number of leg motions in stepping and relating the body support at the end of the step. Systematization of the basic steps of the step-aerobics is quite significant for making a concrete review of the existing basic steps, thus making creation of the step-aerobics lesson easier

  20. Anti-malware software and medical devices.

    Science.gov (United States)

    2010-10-01

    Just as much as healthcare information systems, medical devices need protection against cybersecurity threats. Anti-malware software can help safeguard the devices in your facility-but it has limitations and even risks. Find out what steps you can take to manage anti-malware applications in your devices.

  1. Secure-Network-Coding-Based File Sharing via Device-to-Device Communication

    Directory of Open Access Journals (Sweden)

    Lei Wang

    2017-01-01

    Full Text Available In order to increase the efficiency and security of file sharing in the next-generation networks, this paper proposes a large scale file sharing scheme based on secure network coding via device-to-device (D2D communication. In our scheme, when a user needs to share data with others in the same area, the source node and all the intermediate nodes need to perform secure network coding operation before forwarding the received data. This process continues until all the mobile devices in the networks successfully recover the original file. The experimental results show that secure network coding is very feasible and suitable for such file sharing. Moreover, the sharing efficiency and security outperform traditional replication-based sharing scheme.

  2. Proceedings of the Japan-U.S. workshop P-118 on vacuum technologies for fusion devices

    International Nuclear Information System (INIS)

    Miyahara, A.

    1989-01-01

    Fusion community does not appreciate vacuum technologies to the same extent as accelerator community does. This is because, in the case of accelerators, in particular storage ring systems, the requirement of attaining ultrahigh vacuum in order to avoid collisional loss is well defined, on the other hand, it is not possible to define the requirement so precisely in the case of fusion devices. One of the reasons is that core plasma interacts with vessel wall so strongly and unpredictably that it becomes difficult to identify the role played by individual components. However, in the next step and the next generation machines like CIT, LHS, ITER, FER and NET, vacuum technologies would play more significant roles, because the CIT will introduce tritium in a vacuum vessel, and the aim of the ITER project is to demonstrate particle balance, namely, to achieve steady state operation with D-T fuel. The Japan-U.S. workshop P-118 was held at the Institute of Plasma Physics, Nagoya University, from August 1 to 5, 1988. 33 participants including 4 from the U.S. took part in the workshop. In the plenary session, 12 lectures were given, and also the topics-oriented session on pumping, gauging, remote maintenance, first wall, pump limiter, divertor and others was held. (K.I.)

  3. Efficiency enhancement of the MAPbI3-xClx-based perovskite solar cell by a two-step annealing procedure

    Science.gov (United States)

    Huang, Jin; Wang, Minqiang; Ding, Lei; Deng, Jianping; Yao, Xi

    2016-02-01

    The development of a novel two-step annealing method has contributed to the significantly improved performance of the MAPbI3-xClx based perovskite solar cell (PSC). By utilizing a two-step annealing method, we obtained a high power conversion efficiency (PCE) of 12.72% with a current density (J sc) of 18.35 mA cm-2, an open circuit voltage (V oc) of 0.90 V and a fill factor (FF) of 0.71. Noticeably, the two-step annealed device shows no hysteresis and exhibits a PCE which is approximately 1.2 times greater than that of the one-step annealed device. The improvement in device efficiency is ascribed to the reduced series resistance, increased parallel resistance, better surface coverage, lower leakage current and stronger crystallization of the MAPbI3-xClx perovskite layer.

  4. Strong Stability Preserving Explicit Linear Multistep Methods with Variable Step Size

    KAUST Repository

    Hadjimichael, Yiannis

    2016-09-08

    Strong stability preserving (SSP) methods are designed primarily for time integration of nonlinear hyperbolic PDEs, for which the permissible SSP step size varies from one step to the next. We develop the first SSP linear multistep methods (of order two and three) with variable step size, and prove their optimality, stability, and convergence. The choice of step size for multistep SSP methods is an interesting problem because the allowable step size depends on the SSP coefficient, which in turn depends on the chosen step sizes. The description of the methods includes an optimal step-size strategy. We prove sharp upper bounds on the allowable step size for explicit SSP linear multistep methods and show the existence of methods with arbitrarily high order of accuracy. The effectiveness of the methods is demonstrated through numerical examples.

  5. Automated touch screen device for recording complex rodent behaviors

    Science.gov (United States)

    Mabrouk, O.S.; Dripps, I.J.; Ramani, S.; Chang, C.; Han, J.L.; Rice, KC; Jutkiewicz, E.M.

    2016-01-01

    Background Monitoring mouse behavior is a critical step in the development of modern pharmacotherapies. New Method Here we describe the application of a novel method that utilizes a touch display computer (tablet) and software to detect, record, and report fine motor behaviors. A consumer-grade tablet device is placed in the bottom of a specially made acrylic cage allowing the animal to walk on the device (MouseTrapp). We describe its application in open field (for general locomotor studies) which measures step lengths and velocity. The device can perform light-dark (anxiety) tests by illuminating half of the screen and keeping the other half darkened. A divider is built into the lid of the device allowing the animal free access to either side. Results Treating mice with amphetamine and the delta opioid peptide receptor agonist SNC80 stimulated locomotor activity on the device. Amphetamine increased step velocity but not step length during its peak effect (40–70 min after treatment), thus indicating detection of subtle amphetamine-induced effects. Animals showed a preference (74% of time spent) for the darkened half compared to the illuminated side. Comparison with Existing Method Animals were videotaped within the chamber to compare quadrant crosses to detected motion on the device. The slope, duration and magnitude of quadrant crosses tightly correlated with overall locomotor activity as detected by Mousetrapp. Conclusions We suggest that modern touch display devices such as MouseTrapp will be an important step toward automation of behavioral analyses for characterizing phenotypes and drug effects. PMID:24952323

  6. Interacting steps with finite-range interactions: Analytical approximation and numerical results

    Science.gov (United States)

    Jaramillo, Diego Felipe; Téllez, Gabriel; González, Diego Luis; Einstein, T. L.

    2013-05-01

    We calculate an analytical expression for the terrace-width distribution P(s) for an interacting step system with nearest- and next-nearest-neighbor interactions. Our model is derived by mapping the step system onto a statistically equivalent one-dimensional system of classical particles. The validity of the model is tested with several numerical simulations and experimental results. We explore the effect of the range of interactions q on the functional form of the terrace-width distribution and pair correlation functions. For physically plausible interactions, we find modest changes when next-nearest neighbor interactions are included and generally negligible changes when more distant interactions are allowed. We discuss methods for extracting from simulated experimental data the characteristic scale-setting terms in assumed potential forms.

  7. Radon and material radiopurity assessment for the NEXT double beta decay experiment

    Energy Technology Data Exchange (ETDEWEB)

    Cebrián, S.; Dafni, T.; González-Díaz, D.; Herrera, D. C.; Irastorza, I. G.; Luzón, G.; Ortiz de Solórzano, A.; Villar, J. A. [Laboratorio de Física Nuclear y Astropartículas, Universidad de Zaragoza, C/ Pedro Cerbuna 12, 50009 Zaragoza (Spain); Laboratorio Subterráneo de Canfranc, Paseo de los Ayerbe s/n, 22880 Canfranc Estación, Huesca (Spain); Pérez, J. [Instituto de Física Teórica, UAM/CSIC, Campus de Cantoblanco, 28049 Madrid (Spain); Bandac, I. [Laboratorio Subterráneo de Canfranc, Paseo de los Ayerbe s/n, 22880 Canfranc Estación, Huesca (Spain); Labarga, L. [Dpto. de Física Teórica, Universidad Autónoma de Madrid, Campus de Cantoblanco, 28049 Madrid (Spain); Álvarez, V.; Cárcel, S.; Cervera, A.; Díaz, J.; Ferrario, P.; Gómez-Cadenas, J. J.; Laing, A.; Liubarsky, I.; López-March, N. [Instituto de Física Corpuscular, CSIC & Universitat de València, C/ Catedrático José Beltrán, 2, 46980 Paterna, Valencia (Spain); and others

    2015-08-17

    The ”Neutrino Experiment with a Xenon TPC” (NEXT), intended to investigate the neutrinoless double beta decay using a high-pressure xenon gas TPC filled with Xe enriched in {sup 136}Xe at the Canfranc Underground Laboratory in Spain, requires ultra-low background conditions demanding an exhaustive control of material radiopurity and environmental radon levels. An extensive material screening process is underway for several years based mainly on gamma-ray spectroscopy using ultra-low background germanium detectors in Canfranc but also on mass spectrometry techniques like GDMS and ICPMS. Components from shielding, pressure vessel, electroluminescence and high voltage elements and energy and tracking readout planes have been analyzed, helping in the final design of the experiment and in the construction of the background model. The latest measurements carried out will be presented and the implication on NEXT of their results will be discussed. The commissioning of the NEW detector, as a first step towards NEXT, has started in Canfranc; in-situ measurements of airborne radon levels were taken there to optimize the system for radon mitigation and will be shown too.

  8. NextGEOSS: The Next Generation Data Hub For Earth Observations

    Science.gov (United States)

    Lilja Bye, Bente; De Lathouwer, Bart; Catarino, Nuno; Concalves, Pedro; Trijssenaar, Nicky; Grosso, Nuno; Meyer-Arnek, Julian; Goor, Erwin

    2017-04-01

    The Group on Earth observation embarked on the next 10 year phase with an ambition to streamline and further develop its achievements in building the Global Earth Observing System of Systems (GEOSS). The NextGEOSS project evolves the European vision of GEOSS data exploitation for innovation and business, relying on the three main pillars of engaging communities, delivering technological developments and advocating the use of GEOSS, in order to support the creation and deployment of Earth observation based innovative research activities and commercial services. In this presentation we will present the NextGEOSS concept, a concept that revolves around providing the data and resources to the users communities, together with Cloud resources, seamlessly connected to provide an integrated ecosystem for supporting applications. A central component of NextGEOSS is the strong emphasis put on engaging the communities of providers and users, and bridging the space in between.

  9. Performance analysis in stepped solar still for effluent desalination

    Energy Technology Data Exchange (ETDEWEB)

    Velmurugan, V. [Department of Mechanical Engineering, Infant Jesus College of Engineering, Thoothukudi, Tamil Nadu 628 851 (India); Naveen Kumar, K.J.; Noorul Haq, T.; Srithar, K. [Department of Mechanical Engineering, Thiagarajar College of Engineering, Madurai, Tamil Nadu 625 015 (India)

    2009-09-15

    In this work, a stepped solar still and an effluent settling tank are fabricated and tested for desalinating the textile effluent. The effluent is purified in an effluent settling tank. In this tank, large and fine solid particles are settled and clarified. The settled effluents are used as raw water in the stepped solar still. For better performance, the stepped solar still consists of 50 trays with two different depths. First 25 trays with 10 mm height and the next 25 trays with 5 mm height are used. Fin, sponge, pebble and combination of the above are used for enhancing the productivity of the stepped solar still. A maximum increase in productivity of 98% occurs in stepped solar still when fin, sponge and pebbles are used in this basin. Theoretical analysis agrees well with experimental results. (author)

  10. Nuclear fusion: power for the next century

    International Nuclear Information System (INIS)

    1980-05-01

    The basis of fusion reactions is outlined, with special reference to deuterium and tritium (from lithium, by neutron reaction) as reactants, and the state of research worldwide is indicated. The problems inherent in fusion reactions are discussed, plasma is defined, and the steps to be taken to generate electricity from controlled nuclear fusion are stated. Methods of plasma heating and plasma confinement are considered, leading to a description of the tokamak plasma confinement system. Devices under construction include the JET (Joint European Torus) Undertaking in the UK. Plans and possibilities for fusion reactors are discussed. (U.K.)

  11. Effects of radiation on MOS structures and silicon devices

    International Nuclear Information System (INIS)

    Braeunig, D.; Fahrner, W.

    1983-02-01

    A comprehensive view of radiation effects on MOS structures and silicon devices is given. In the introduction, the interaction of radiation with semiconductor material is presented. In the next section, the electrical degradation of semiconductor devices due to this interaction is discussed. The commonly used hardening techniques are shown. The last section deals with testing of radiation hardness of devices. (orig.) [de

  12. Operation control device under radiation exposure

    International Nuclear Information System (INIS)

    Kimura, Kiichi; Murakami, Toichi.

    1994-01-01

    The device of the present invention performs smooth progress of operation by remote control for a plurality of operations in periodical inspections in controlled areas of a nuclear power plant, thereby reducing the operator's exposure dose. Namely, the device monitors the progressing state of the operation by displaying the progress of operation on a CRT of a centralized control device present in a low dose area remote from an operation field through an ITV camera disposed in the vicinity of the operation field. Further, operation sequence and operation instruction procedures previously inputted in the device are indicated to the operation field through an operation instruction outputting device (field CRT) in accordance with the progress of the operation steps. On the other hand, the operation progress can be aided by inputting information from the operation field such as start or completion of the operation steps. Further, the device of the present invention can monitor the change of operation circumstances and exposure dose of operators based on the information from a radiation dose measuring device disposed in the operation circumstance and to individual operators. (I.S.)

  13. Study of the effect of heavy ion energy on the sensitivity of electronic devices

    International Nuclear Information System (INIS)

    Raine, M.

    2011-01-01

    This thesis studies the sensitivity of advanced electronic devices in radiative environments. The work deals with the detailed modeling of the deposited energy induced by heavy-ion in matter, and the influence of taking it into account in the tools simulating the response of irradiated devices. To do so, a simulation chain was developed, combining different calculation codes at various scales. In a first step, the particle-matter interaction code Geant4 is used to model the heavy ion track. These tracks are then implemented in a TCAD simulator, in order to study the response of elementary transistors to these detailed energy deposits. This step is completed with experimental measurements. Finally, the study is extended to the circuit level, by interfacing the heavy ion tracks with a SEE prediction tool. These different steps evidence the need for taking into account the radial extension of the ion track to all simulation levels, to adequately model the response of advanced devices under heavy ion irradiations. (author) [fr

  14. Next generation PWR

    International Nuclear Information System (INIS)

    Tanaka, Toshihiko; Fukuda, Toshihiko; Usui, Shuji

    2001-01-01

    Development of LWR for power generation in Japan has been intended to upgrade its reliability, safety, operability, maintenance and economy as well as to increase its capacity in order, since nuclear power generation for commercial use was begun on 1970, to steadily increase its generation power. And, in Japan, ABWR (advanced BWR) of the most promising LWR in the world, was already used actually and APWR (advanced PWR) with the largest output in the world is also at a step of its actual use. And, development of the APWR in Japan was begun on 1980s, and is at a step of plan on construction of its first machine at early of this century. However, by large change of social affairs, economy of nuclear power generation is extremely required, to be positioned at an APWR improved development reactor promoted by collaboration of five PWR generation companies and the Mitsubishi Electric Co., Ltd. Therefore, on its development, investigation on effect of change in social affairs on nuclear power stations was at first carried out, to establish a design requirement for the next generation PWR. Here were described on outline, reactor core design, safety concept, and safety evaluation of APWR+ and development of an innovative PWR. (G.K.)

  15. Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila

    Directory of Open Access Journals (Sweden)

    Patrice D. Cani

    2017-09-01

    Full Text Available Metabolic disorders associated with obesity and cardiometabolic disorders are worldwide epidemic. Among the different environmental factors, the gut microbiota is now considered as a key player interfering with energy metabolism and host susceptibility to several non-communicable diseases. Among the next-generation beneficial microbes that have been identified, Akkermansia muciniphila is a promising candidate. Indeed, A. muciniphila is inversely associated with obesity, diabetes, cardiometabolic diseases and low-grade inflammation. Besides the numerous correlations observed, a large body of evidence has demonstrated the causal beneficial impact of this bacterium in a variety of preclinical models. Translating these exciting observations to human would be the next logic step and it now appears that several obstacles that would prevent the use of A. muciniphila administration in humans have been overcome. Moreover, several lines of evidence indicate that pasteurization of A. muciniphila not only increases its stability but more importantly increases its efficacy. This strongly positions A. muciniphila in the forefront of next-generation candidates for developing novel food or pharma supplements with beneficial effects. Finally, a specific protein present on the outer membrane of A. muciniphila, termed Amuc_1100, could be strong candidate for future drug development. In conclusion, as plants and its related knowledge, known as pharmacognosy, have been the source for designing drugs over the last century, we propose that microbes and microbiomegnosy, or knowledge of our gut microbiome, can become a novel source of future therapies.

  16. Graphene resistive random memory — the promising memory device in next generation

    International Nuclear Information System (INIS)

    Wang Xue-Feng; Zhao Hai-Ming; Yang Yi; Ren Tian-Ling

    2017-01-01

    Graphene-based resistive random access memory (GRRAM) has grasped researchers’ attention due to its merits compared with ordinary RRAM. In this paper, we briefly review different types of GRRAMs. These GRRAMs can be divided into two categories: graphene RRAM and graphene oxide (GO)/reduced graphene oxide (rGO) RRAM. Using graphene as the electrode, GRRAM can own many good characteristics, such as low power consumption, higher density, transparency, SET voltage modulation, high uniformity, and so on. Graphene flakes sandwiched between two dielectric layers can lower the SET voltage and achieve multilevel switching. Moreover, the GRRAM with rGO and GO as the dielectric or electrode can be simply fabricated. Flexible and high performance RRAM and GO film can be modified by adding other materials layer or making a composite with polymer, nanoparticle, and 2D materials to further improve the performance. Above all, GRRAM shows huge potential to become the next generation memory. (topical reviews)

  17. Semiconductor device models for circuit simulation power electronics; Modeles de composants semiconducteurs pour la simulation des circuits en electronique de puissance

    Energy Technology Data Exchange (ETDEWEB)

    Berraies, M.O.

    1998-09-10

    In this thesis, an alternative strategy based on a regional approach to modeling and a new partition of the model library in the simulation is proposed. The main objective is to substitute for the usual concept of `one device, on model` that of an adaptable assembly of a limited number of submodels associated with well-identified regions of semiconductor structures. In other words, the library will only contain the primitive building-blocks of the power device models. This strategy guarantees the compatibility of the various semiconductor models in terms of physical concepts, validity domain, accuracy, homogeneity of parameter identification procedures, similarly of implementation in the simulator. This approach has been applied to PIN diodes and IGBTs for experimental validation. The next step consisted on the simulation of circuit involving several interacting devices. A simple IGBT/PIN diode chopper cell has been chosen. The results obtained compare well with experiment. This demonstrates the consistency of the proposed approach. (author) 43 refs.

  18. Microfluidic devices and methods for integrated flow cytometry

    Science.gov (United States)

    Srivastava, Nimisha [Goleta, CA; Singh, Anup K [Danville, CA

    2011-08-16

    Microfluidic devices and methods for flow cytometry are described. In described examples, various sample handling and preparation steps may be carried out within a same microfluidic device as flow cytometry steps. A combination of imaging and flow cytometry is described. In some examples, spiral microchannels serve as incubation chambers. Examples of automated sample handling and flow cytometry are described.

  19. Mechanistic evaluation of the pros and cons of digital RT-LAMP for HIV-1 viral load quantification on a microfluidic device and improved efficiency via a two-step digital protocol.

    Science.gov (United States)

    Sun, Bing; Shen, Feng; McCalla, Stephanie E; Kreutz, Jason E; Karymov, Mikhail A; Ismagilov, Rustem F

    2013-02-05

    Here we used a SlipChip microfluidic device to evaluate the performance of digital reverse transcription-loop-mediated isothermal amplification (dRT-LAMP) for quantification of HIV viral RNA. Tests are needed for monitoring HIV viral load to control the emergence of drug resistance and to diagnose acute HIV infections. In resource-limited settings, in vitro measurement of HIV viral load in a simple format is especially needed, and single-molecule counting using a digital format could provide a potential solution. We showed here that when one-step dRT-LAMP is used for quantification of HIV RNA, the digital count is lower than expected and is limited by the yield of desired cDNA. We were able to overcome the limitations by developing a microfluidic protocol to manipulate many single molecules in parallel through a two-step digital process. In the first step we compartmentalize the individual RNA molecules (based on Poisson statistics) and perform reverse transcription on each RNA molecule independently to produce DNA. In the second step, we perform the LAMP amplification on all individual DNA molecules in parallel. Using this new protocol, we increased the absolute efficiency (the ratio between the concentration calculated from the actual count and the expected concentration) of dRT-LAMP 10-fold, from ∼2% to ∼23%, by (i) using a more efficient reverse transcriptase, (ii) introducing RNase H to break up the DNA:RNA hybrid, and (iii) adding only the BIP primer during the RT step. We also used this two-step method to quantify HIV RNA purified from four patient samples and found that in some cases, the quantification results were highly sensitive to the sequence of the patient's HIV RNA. We learned the following three lessons from this work: (i) digital amplification technologies, including dLAMP and dPCR, may give adequate dilution curves and yet have low efficiency, thereby providing quantification values that underestimate the true concentration. Careful

  20. Thermonuclear device

    International Nuclear Information System (INIS)

    Tezuka, Masaru.

    1993-01-01

    Protrusions and recesses are formed to a vacuum vessel and toroidal magnetic coils, and they are engaged. Since the vacuum vessel is generally supported firmly by a rack or the like by support legs, the toroidal magnetic field coils can be certainly supported against tumbling force. Then, there can be attained strong supports for the toroidal magnetic field coils, in addition to support by wedges on the side of inboard and support by share panels on the side of outboard, capable of withstanding great electromagnetic forces which may occur in large-scaled next-generation devices. That is, toroidal magnetic field coils excellent from a view point of deformation and stress can be obtained, to provide a thermonuclear device of higher reliability. (N.H.)

  1. Organic optoelectronics:materials,devices and applications

    Institute of Scientific and Technical Information of China (English)

    LIU Yi; CUI Tian-hong

    2005-01-01

    The interest in organic materials for optoelectronic devices has been growing rapidly in the last two decades. This growth has been propelled by the exciting advances in organic thin films for displays, low-cost electronic circuits, etc. An increasing number of products employing organic electronic devices have become commercialized, which has stimulated the age of organic optoelectronics. This paper reviews the recent progress in organic optoelectronic technology. First, organic light emitting electroluminescent materials are introduced. Next, the three kinds of most important organic optoelectronic devices are summarized, including light emitting diode, organic photovoltaic cell, and photodetectors. The various applications of these devices are also reviewed and discussed in detail. Finally, the market and future development of optoelectronic devices are also demonstrated.

  2. Tritium Removal from Carbon Plasma Facing Components

    International Nuclear Information System (INIS)

    Skinner, C.H.; Coad, J.P.; Federici, G.

    2003-01-01

    Tritium removal is a major unsolved development task for next-step devices with carbon plasma-facing components. The 2-3 order of magnitude increase in duty cycle and associated tritium accumulation rate in a next-step tokamak will place unprecedented demands on tritium removal technology. The associated technical risk can be mitigated only if suitable removal techniques are demonstrated on tokamaks before the construction of a next-step device. This article reviews the history of codeposition, the tritium experience of TFTR (Tokamak Fusion Test Reactor) and JET (Joint European Torus) and the tritium removal rate required to support ITER's planned operational schedule. The merits and shortcomings of various tritium removal techniques are discussed with particular emphasis on oxidation and laser surface heating

  3. The apeNEXT project

    International Nuclear Information System (INIS)

    Belletti, F.; Bodin, F.; Boucaud, Ph.; Cabibbo, N.; Lonardo, A.; De Luca, S.; Lukyanov, M.; Micheli, J.; Morin, L.; Pene, O.; Pleiter, D.; Rapuano, F.; Rossetti, D.; Schifano, S.F.; Simma, H.; Tripiccione, R.; Vicini, P.

    2006-01-01

    Numerical simulations in theoretical high-energy physics (Lattice QCD) require huge computing resources. Several generations of massively parallel computers optimised for these applications have been developed within the APE (array processor experiment) project. Large prototype systems of the latest generation, apeNEXT, are currently being assembled and tested. This contribution explains how the apeNEXT architecture is optimised for Lattice QCD, provides an overview of the hardware and software of apeNEXT, and describes its new features, like the SPMD programming model and the C compiler

  4. Comparison of step-by-step kinematics in repeated 30m sprints in female soccer players.

    Science.gov (United States)

    van den Tillaar, Roland

    2018-01-04

    The aim of this study was to compare kinematics in repeated 30m sprints in female soccer players. Seventeen subjects performed seven 30m sprints every 30s in one session. Kinematics were measured with an infrared contact mat and laser gun, and running times with an electronic timing device. The main findings were that sprint times increased in the repeated sprint ability test. The main changes in kinematics during the repeated sprint ability test were increased contact time and decreased step frequency, while no change in step length was observed. The step velocity increased in almost each step until the 14, which occurred around 22m. After this, the velocity was stable until the last step, when it decreased. This increase in step velocity was mainly caused by the increased step length and decreased contact times. It was concluded that the fatigue induced in repeated 30m sprints in female soccer players resulted in decreased step frequency and increased contact time. Employing this approach in combination with a laser gun and infrared mat for 30m makes it very easy to analyse running kinematics in repeated sprints in training. This extra information gives the athlete, coach and sports scientist the opportunity to give more detailed feedback and help to target these changes in kinematics better to enhance repeated sprint performance.

  5. Next step, the Tour de France?

    CERN Multimedia

    Anaïs Schaeffer

    2013-01-01

    The penultimate stage of the 2013 Tour de France, the Annecy-Semnoz time-trial, has already been won – by a CERN staff member!     In keeping with tradition, the organisers of the Tour de France organise another race, the Étape du Tour, which is open to the general public and follows the actual route of an official stage of the Tour proper. This year, the chosen venue was Annecy and its neighbouring mountain, Le Semnoz, which played host to 11,000 cycling enthusiasts from all parts. This penultimate stage of the 2013 Tour will be raced by the professionals on 20 July. The public race was won by Nicolas Roux, an experienced cyclist and member of CERN’s GS-IS Group, who devoured the 128-km course in just 4 hours and 15 minutes, nine seconds ahead of cycling champion Julien Absalon. “I just managed to overhaul Julien Absalon 500 m before the finishing line,” Nicolas recounts. “It was a fantastic race!” Come rain o...

  6. The international thermonuclear reactor project

    International Nuclear Information System (INIS)

    James, T.R.

    1993-01-01

    The International Thermonuclear Experimental Reactor Project is a 6-year collaborative effort involving the U.S., Europe, Japan, and the Russian Federation to produce a detailed engineering design for the next-step fusion device

  7. Integrated Modelling - the next steps (Invited)

    Science.gov (United States)

    Moore, R. V.

    2010-12-01

    Integrated modelling (IM) has made considerable advances over the past decade but it has not yet been taken up as an operational tool in the way that its proponents had hoped. The reasons why will be discussed in Session U17. This talk will propose topics for a research and development programme and suggest an institutional structure which, together, could overcome the present obstacles. Their combined aim would be first to make IM into an operational tool useable by competent public authorities and commercial companies and, in time, to see it evolve into the modelling equivalent of Google Maps, something accessible and useable by anyone with a PC or an iphone and an internet connection. In a recent study, a number of government agencies, water authorities and utilities applied integrated modelling to operational problems. While the project demonstrated that IM could be used in an operational setting and had benefit, it also highlighted the advances that would be required for its widespread uptake. These were: greatly improving the ease with which models could be a) made linkable, b) linked and c) run; developing a methodology for applying integrated modelling; developing practical options for calibrating and validating linked models; addressing the science issues that arise when models are linked; extending the range of modelling concepts that can be linked; enabling interface standards to pass uncertainty information; making the interface standards platform independent; extending the range of platforms to include those for high performance computing; developing the concept of modelling components as web services; separating simulation code from the model’s GUI, so that all the results from the linked models can be viewed through a single GUI; developing scenario management systems so that that there is an audit trail of the version of each model and dataset used in each linked model run. In addition to the above, there is a need to build a set of integrated

  8. Particle accelerators: the next big step

    International Nuclear Information System (INIS)

    Lawson, J.

    1982-01-01

    Ideas which are currently under discussion for increasing the present energy range of particle accelerators but which are also economical in resources and do not demand elaborate techniques, are examined. Among the possible methods reviewed are the use of laser beams, the electron ring concept, and the use of wake fields left by electrons in storage rings. (U.K.)

  9. Embodied cognition: Taking the next step

    Directory of Open Access Journals (Sweden)

    Roel M Willems

    2012-12-01

    Full Text Available Recent years have seen a large amount of empirical studies related to ‘embodied cognition’. While interesting and valuable, there is something dissatisfying with the current state of affairs in this research domain. Hypotheses tend to be underspecified, testing in general terms for embodied versus disembodied processing. The lack of specificity of current hypotheses can easily lead to an erosion of the embodiment concept, and result in a situation in which essentially any effect is taken as positive evidence. Such erosion is not helpful to the field and does not do justice to the importance of embodiment. Here we want to take stock, and formulate directions for how it can be studied in a more fruitful fashion. As an example we will describe few example studies that have investigated the role of sensori-motor systems in the coding of meaning (‘embodied semantics’. Instead of focusing on the dichotomy between embodied and disembodied theories, we suggest that the field move forward and ask how and when sensori-motor systems and behavior are involved in cognition.

  10. Ignition in the next step tokamak

    International Nuclear Information System (INIS)

    Johner, J.

    1990-07-01

    A 1/2-D model for thermal equilibrium of a thermonuclear plasma with transport described by an empirical global energy confinement time is described. Ignition in NET and ITER is studied for a number of energy confinement time scaling expressions. Ignited operation of these machines at the design value of the neutron wall load is shown to satisfy both beta and density constraints. The value of the confinement time enhancement factor required for such operation is found to be lower for the more recently proposed scaling expressions than it is for the oldest ones. With such new scalings, ignition could be obtained in H-mode in NET and ITER even with relatively flat density profiles

  11. FOOTPRINTS FOR SUSTAINABILITY: THE NEXT STEPS

    Science.gov (United States)

    This paper discusses the strengths and weaknesses of the ecological footprint as an ecological accounting method, points out research needs for improvement of the analysis, and suggests potential new applications.

  12. Combined SRCT & FXCT - The next steps

    Science.gov (United States)

    Hall, C.; Acres, R. G.; Winnett, A.; Wang, F.

    2016-03-01

    One of the goals in developing synchrotron radiation x-ray computed tomography (SRCT) for biomedical specimens, is allowing particular tissues and cell types to be marked in the images. This is equivalent to the staining in histology, which enables researchers to visualise and measure tissue structure and biochemical processes within the specimen. Some progress in this direction for SRCT is being made, using a variety of contrast agents that alter the natural x-ray attenuation of the marked tissue [1]. However there are limits to the usefulness of these attenuation altering techniques. Often high concentrations of potentially disruptive chemicals are required with reduced compatibility for in-vivo studies. Another image highlighting technique which might prove more sensitive is x-ray fluorescence imaging. In this case usually endogenous elemental markers are visualised. We would like to develop a lower resolution, but wider field of view means of three-dimensional (3-D) fluorescence imaging compatible with SRCT. We have previously proposed a technique in which x-ray fluorescence CT (FXCT) and SRCT data can be collected simultaneously [2]. This work resulted in proof of concept modelling, and a simple experiment test system. We show data here which demonstrate a two-dimensional (2-D) reconstruction of an iodine fluorescence map from a phantom. Measurements were performed with a fixed beam modulating mask using the Imaging and Medical beam line (IMBL) at the Australian Synchrotron. Fluorescence data was obtained during a CT scan using a single point detector, while transmission data was simultaneously collected using an area detector. A maximum likelihood expectation maximisation (MLEM) iterative algorithm was used to reconstruct the fluorescence map. We report on technique development and now believe compressive sensing (CS) imaging techniques suit SRCT and may overcome the issues encountered so far in combining SRCT and FXCT.

  13. Bio-Inspired Photon Absorption and Energy Transfer for Next Generation Photovoltaic Devices

    Science.gov (United States)

    Magsi, Komal

    Nature's solar energy harvesting system, photosynthesis, serves as a model for photon absorption, spectra broadening, and energy transfer. Photosynthesis harvests light far differently than photovoltaic cells. These differences offer both engineering opportunity and scientific challenges since not all of the natural photon absorption mechanisms have been understood. In return, solar cells can be a very sensitive probe for the absorption characteristics of molecules capable of transferring charge to a conductive interface. The objective of this scientific work is the advancement of next generation photovoltaics through the development and application of natural photo-energy transfer processes. Two scientific methods were used in the development and application of enhancing photon absorption and transfer. First, a detailed analysis of photovoltaic front surface fluorescent spectral modification and light scattering by hetero-structure was conducted. Phosphor based spectral down-conversion is a well-known laser technology. The theoretical calculations presented here indicate that parasitic losses and light scattering within the spectral range are large enough to offset any expected gains. The second approach for enhancing photon absorption is based on bio-inspired mechanisms. Key to the utilization of these natural processes is the development of a detailed scientific understanding and the application of these processes to cost effective systems and devices. In this work both aspects are investigated. Dye type solar cells were prepared and tested as a function of Chlorophyll (or Sodium-Copper Chlorophyllin) and accessory dyes. Forster has shown that the fluorescence ratio of Chlorophyll is modified and broadened by separate photon absorption (sensitized absorption) through interaction with nearby accessory pigments. This work used the dye type solar cell as a diagnostic tool by which to investigate photon absorption and photon energy transfer. These experiments shed

  14. Aerospace Concurrent Engineering Design Teams: Current State, Next Steps and a Vision for the Future

    Science.gov (United States)

    Hihn, Jairus; Chattopadhyay, Debarati; Karpati, Gabriel; McGuire, Melissa; Borden, Chester; Panek, John; Warfield, Keith

    2011-01-01

    Over the past sixteen years, government aerospace agencies and aerospace industry have developed and evolved operational concurrent design teams to create novel spaceflight mission concepts and designs. These capabilities and teams, however, have evolved largely independently. In today's environment of increasingly complex missions with limited budgets it is becoming readily apparent that both implementing organizations and today's concurrent engineering teams will need to interact more often than they have in the past. This will require significant changes in the current state of practice. This paper documents the findings from a concurrent engineering workshop held in August 2010 to identify the key near term improvement areas for concurrent engineering capabilities and challenges to the long-term advancement of concurrent engineering practice. The paper concludes with a discussion of a proposed vision for the evolution of these teams over the next decade.

  15. Validation of the ADAMO Care Watch for step counting in older adults.

    Science.gov (United States)

    Magistro, Daniele; Brustio, Paolo Riccardo; Ivaldi, Marco; Esliger, Dale Winfield; Zecca, Massimiliano; Rainoldi, Alberto; Boccia, Gennaro

    2018-01-01

    Accurate measurement devices are required to objectively quantify physical activity. Wearable activity monitors, such as pedometers, may serve as affordable and feasible instruments for measuring physical activity levels in older adults during their normal activities of daily living. Currently few available accelerometer-based steps counting devices have been shown to be accurate at slow walking speeds, therefore there is still lacking appropriate devices tailored for slow speed ambulation, typical of older adults. This study aimed to assess the validity of step counting using the pedometer function of the ADAMO Care Watch, containing an embedded algorithm for measuring physical activity in older adults. Twenty older adults aged ≥ 65 years (mean ± SD, 75±7 years; range, 68-91) and 20 young adults (25±5 years, range 20-40), wore a care watch on each wrist and performed a number of randomly ordered tasks: walking at slow, normal and fast self-paced speeds; a Timed Up and Go test (TUG); a step test and ascending/descending stairs. The criterion measure was the actual number of steps observed, counted with a manual tally counter. Absolute percentage error scores, Intraclass Correlation Coefficients (ICC), and Bland-Altman plots were used to assess validity. ADAMO Care Watch demonstrated high validity during slow and normal speeds (range 0.5-1.5 m/s) showing an absolute error from 1.3% to 1.9% in the older adult group and from 0.7% to 2.7% in the young adult group. The percentage error for the 30-metre walking tasks increased with faster pace in both young adult (17%) and older adult groups (6%). In the TUG test, there was less error in the steps recorded for older adults (1.3% to 2.2%) than the young adults (6.6% to 7.2%). For the total sample, the ICCs for the ADAMO Care Watch for the 30-metre walking tasks at each speed and for the TUG test were ranged between 0.931 to 0.985. These findings provide evidence that the ADAMO Care Watch demonstrated highly accurate

  16. Security Frameworks for Machine-to-Machine Devices and Networks

    Science.gov (United States)

    Demblewski, Michael

    Attacks against mobile systems have escalated over the past decade. There have been increases of fraud, platform attacks, and malware. The Internet of Things (IoT) offers a new attack vector for Cybercriminals. M2M contributes to the growing number of devices that use wireless systems for Internet connection. As new applications and platforms are created, old vulnerabilities are transferred to next-generation systems. There is a research gap that exists between the current approaches for security framework development and the understanding of how these new technologies are different and how they are similar. This gap exists because system designers, security architects, and users are not fully aware of security risks and how next-generation devices can jeopardize safety and personal privacy. Current techniques, for developing security requirements, do not adequately consider the use of new technologies, and this weakens countermeasure implementations. These techniques rely on security frameworks for requirements development. These frameworks lack a method for identifying next generation security concerns and processes for comparing, contrasting and evaluating non-human device security protections. This research presents a solution for this problem by offering a novel security framework that is focused on the study of the "functions and capabilities" of M2M devices and improves the systems development life cycle for the overall IoT ecosystem.

  17. Improvements on non-equilibrium and transport Green function techniques: The next-generation TRANSIESTA

    OpenAIRE

    Papior, Nick Rübner; Lorente, Nicolás; Frederiksen, Thomas; García, Alberto; Brandbyge, Mads

    2017-01-01

    We present novel methods implemented within the non-equilibrium Green function code (NEGF) TRANSIESTA based on density functional theory (DFT). Our flexible, next-generation DFT–NEGF code handles devices with one or multiple electrodes (Ne≥1) with individual chemical potentials and electronic temperatures. We describe its novel methods for electrostatic gating, contour optimizations, and assertion of charge conservation, as well as the newly implemented algorithms for optimized and scalable m...

  18. Assessing software quality at each step of its life-cycle to enhance reliability of control systems

    International Nuclear Information System (INIS)

    Hardion, V.; Buteau, A.; Leclercq, N.; Abeille, G.; Pierre-Joseph, Z.; Le, S.

    2012-01-01

    A distributed software control system aims to enhance the upgrade ability and reliability by sharing responsibility between several components. The disadvantage is that it makes it harder to detect problems on a significant number of modules. With Kaizen in mind we have chosen to continuously invest in automation to obtain a complete overview of software quality despite the growth of legacy code. The development process has already been mastered by staging each life-cycle step thanks to a continuous integration server based on JENKINS and MAVEN. We enhanced this process, focusing on 3 objectives: Automatic Test, Static Code Analysis and Post-Mortem Supervision. Now, the build process automatically includes a test section to detect regressions, incorrect behaviour and integration incompatibility. The in-house TANGOUNIT project satisfies the difficulties of testing distributed components such as Tango Devices. In the next step, the programming code has to pass a complete code quality check-up. The SONAR quality server has been integrated in the process, to collect each static code analysis and display the hot topics on summary web pages. Finally, the integration of Google BREAKPAD in every TANGO Devices gives us essential statistics from crash reports and enables us to replay the crash scenarios at any time. We have already gained greater visibility on current developments. Some concrete results will be presented including reliability enhancement, better management of subcontracted software development, quicker adoption of coding standards by new developers and understanding of impacts when moving to a new technology. (authors)

  19. Step-height standards based on the rapid formation of monolayer steps on the surface of layered crystals

    Energy Technology Data Exchange (ETDEWEB)

    Komonov, A.I. [Rzhanov Institute of Semiconductor Physics, Siberian Branch of the Russian Academy of Sciences (ISP SBRAS), pr. Lavrentieva 13, Novosibirsk 630090 (Russian Federation); Prinz, V.Ya., E-mail: prinz@isp.nsc.ru [Rzhanov Institute of Semiconductor Physics, Siberian Branch of the Russian Academy of Sciences (ISP SBRAS), pr. Lavrentieva 13, Novosibirsk 630090 (Russian Federation); Seleznev, V.A. [Rzhanov Institute of Semiconductor Physics, Siberian Branch of the Russian Academy of Sciences (ISP SBRAS), pr. Lavrentieva 13, Novosibirsk 630090 (Russian Federation); Kokh, K.A. [Sobolev Institute of Geology and Mineralogy, Siberian Branch of the Russian Academy of Sciences (IGM SB RAS), pr. Koptyuga 3, Novosibirsk 630090 (Russian Federation); Shlegel, V.N. [Nikolaev Institute of Inorganic Chemistry, Siberian Branch of the Russian Academy of Sciences (NIIC SB RAS), pr. Lavrentieva 3, Novosibirsk 630090 (Russian Federation)

    2017-07-15

    Highlights: • Easily reproducible step-height standard for SPM calibrations was proposed. • Step-height standard is monolayer steps on the surface of layered single crystal. • Long-term change in surface morphology of Bi{sub 2}Se{sub 3} and ZnWO{sub 4} was investigated. • Conducting surface of Bi{sub 2}Se{sub 3} crystals appropriate for calibrating STM. • Ability of robust SPM calibrations under ambient conditions were demonstrated. - Abstract: Metrology is essential for nanotechnology, especially for structures and devices with feature sizes going down to nm. Scanning probe microscopes (SPMs) permits measurement of nanometer- and subnanometer-scale objects. Accuracy of size measurements performed using SPMs is largely defined by the accuracy of used calibration measures. In the present publication, we demonstrate that height standards of monolayer step (∼1 and ∼0.6 nm) can be easily prepared by cleaving Bi{sub 2}Se{sub 3} and ZnWO{sub 4} layered single crystals. It was shown that the conducting surface of Bi{sub 2}Se{sub 3} crystals offers height standard appropriate for calibrating STMs and for testing conductive SPM probes. Our AFM study of the morphology of freshly cleaved (0001) Bi{sub 2}Se{sub 3} surfaces proved that such surfaces remained atomically smooth during a period of at least half a year. The (010) surfaces of ZnWO{sub 4} crystals remained atomically smooth during one day, but already two days later an additional nanorelief of amplitude ∼0.3 nm appeared on those surfaces. This relief, however, did not further grow in height, and it did not hamper the calibration. Simplicity and the possibility of rapid fabrication of the step-height standards, as well as their high stability, make these standards available for a great, permanently growing number of users involved in 3D printing activities.

  20. Transport Imaging for the Study of Quantum Scattering Phenomena in Next Generation Semiconductor Devices

    National Research Council Canada - National Science Library

    Bradley, Frank M

    2005-01-01

    ...) and highly efficient solar cells. A novel technique has been developed utilizing direct imaging of electron/hole recombination via an optical microscope and a high sensitivity charge coupled device coupled to a scanning electron...

  1. Performance of back supportless CCDs for the NeXT mission

    International Nuclear Information System (INIS)

    Takagi, Shin-ichiro; Go Tsuru, Takeshi; Matsumoto, Hironori; Koyama, Katsuji; Tsunemi, Hiroshi; Miyata, Emi; Miyazaki, Satoshi; Kamata, Yukiko; Muramatsu, Masaharu; Suzuki, Hisanori; Miyaguchi, Kazuhisa

    2005-01-01

    New X-ray Telescope (NeXT) will be the next Japanese X-ray astronomical satellite, which will be launched around 2010. A multilayer super mirror will give NeXT a large effective area across the 0.1-80keV band. This wide bandpass requires a focal plane detector that is also sensitive along the entire energy band. As the focal plane detector for NeXT, we have been developing a Wideband hybrid X-ray Imager (WXI) consisting of X-ray CCDs and pixelized CdTe detector. The X-ray CCD of the WXI is required to maintain high quantum efficiency up to the high-energy band while allowing hard X-rays to pass undetected through the depletion (sensitive) layer. In order to meet these requirements, we have been developing a back supportless CCD (BS-CCD) which has a thick depletion layer, a thinned Si wafer and a back supportless structure. As the first step, we manufactured a test model of BS-CCD in order to (1) learn the handling and thinning process and (2) confirm that there is no change of the performance. For the mechanical strength and the safe handling of the wafer, we decided to thin the wafer to ∼200μm. We verified the thickness of the depletion layer and wafer of the BS-CCD to be about 70 and 190μm, respectively. The energy resolution at 5.9keV of 144eV and the read-out noise of 7 electrons (rms) are equal to those of an un-thinned CCD, hence, we confirmed that our thinning process has no effect on the performance

  2. Mobile device security for dummies

    CERN Document Server

    Campagna, Rich; Krishnan, Ashwin

    2011-01-01

    The information you need to avoid security threats on corporate mobile devices Mobile devices have essentially replaced computers for corporate users who are on the go and there are millions of networks that have little to no security. This essential guide walks you through the steps for securing a network and building a bulletproof framework that will protect and support mobile devices in the enterprise. Featuring real-world case scenarios, this straightforward guide shares invaluable advice for protecting mobile devices from the loss of sensitive and confidential corporate informati

  3. Enhanced piezoelectric effect at the edges of stepped molybdenum disulfide nanosheets.

    Science.gov (United States)

    Song, Xiaoxue; Hui, Fei; Gilmore, Keith; Wang, Bingru; Jing, Guangyin; Fan, Zhongchao; Grustan-Gutierrez, Enric; Shi, Yuanyuan; Lombardi, Lucia; Hodge, Stephen A; Ferrari, Andrea C; Lanza, Mario

    2017-05-18

    The development of piezoelectric layered materials may be one of the key elements enabling expansion of nanotechnology, as they offer a solution for the construction of efficient transducers for a wide range of applications, including self-powered devices. Here, we investigate the piezoelectric effect in multilayer (ML) stepped MoS 2 flakes obtained by liquid-phase exfoliation, which is especially interesting because it may allow the scalable fabrication of electronic devices using large area deposition techniques (e.g. solution casting, spray coating, inkjet printing). By using a conductive atomic force microscope we map the piezoelectricity of the MoS 2 flakes at the nanoscale. Our experiments demonstrate the presence of electrical current densities above 100 A cm -2 when the flakes are strained in the absence of bias, and the current increases proportional to the bias. Simultaneously collected topographic and current maps demonstrate that the edges of stepped ML MoS 2 flakes promote the piezoelectric effect, where the largest currents are observed. Density functional theory calculations are consistent with the ring-like piezoelectric potential generated when the flakes are strained, as well as the enhanced piezoelectric effect at edges. Our results pave the way to the design of piezoelectric devices using layered materials.

  4. Challenges for single molecule electronic devices with nanographene and organic molecules. Do single molecules offer potential as elements of electronic devices in the next generation?

    Science.gov (United States)

    Enoki, Toshiaki; Kiguchi, Manabu

    2018-03-01

    Interest in utilizing organic molecules to fabricate electronic materials has existed ever since organic (molecular) semiconductors were first discovered in the 1950s. Since then, scientists have devoted serious effort to the creation of various molecule-based electronic systems, such as molecular metals and molecular superconductors. Single-molecule electronics and the associated basic science have emerged over the past two decades and provided hope for the development of highly integrated molecule-based electronic devices in the future (after the Si-based technology era has ended). Here, nanographenes (nano-sized graphene) with atomically precise structures are among the most promising molecules that can be utilized for electronic/spintronic devices. To manipulate single small molecules for an electronic device, a single molecular junction has been developed. It is a powerful tool that allows even small molecules to be utilized. External electric, magnetic, chemical, and mechanical perturbations can change the physical and chemical properties of molecules in a way that is different from bulk materials. Therefore, the various functionalities of molecules, along with changes induced by external perturbations, allows us to create electronic devices that we cannot create using current top-down Si-based technology. Future challenges that involve the incorporation of condensed matter physics, quantum chemistry calculations, organic synthetic chemistry, and electronic device engineering are expected to open a new era in single-molecule device electronic technology.

  5. Metal-Organic Frameworks as Active Materials in Electronic Sensor Devices.

    Science.gov (United States)

    Campbell, Michael G; Dincă, Mircea

    2017-05-12

    In the past decade, advances in electrically conductive metal-organic frameworks (MOFs) and MOF-based electronic devices have created new opportunities for the development of next-generation sensors. Here we review this rapidly-growing field, with a focus on the different types of device configurations that have allowed for the use of MOFs as active components of electronic sensor devices.

  6. Improved perovskite phototransistor prepared using multi-step annealing method

    Science.gov (United States)

    Cao, Mingxuan; Zhang, Yating; Yu, Yu; Yao, Jianquan

    2018-02-01

    Organic-inorganic hybrid perovskites with good intrinsic physical properties have received substantial interest for solar cell and optoelectronic applications. However, perovskite film always suffers from a low carrier mobility due to its structural imperfection including sharp grain boundaries and pinholes, restricting their device performance and application potential. Here we demonstrate a straightforward strategy based on multi-step annealing process to improve the performance of perovskite photodetector. Annealing temperature and duration greatly affects the surface morphology and optoelectrical properties of perovskites which determines the device property of phototransistor. The perovskite films treated with multi-step annealing method tend to form highly uniform, well-crystallized and high surface coverage perovskite film, which exhibit stronger ultraviolet-visible absorption and photoluminescence spectrum compare to the perovskites prepared by conventional one-step annealing process. The field-effect mobilities of perovskite photodetector treated by one-step direct annealing method shows mobility as 0.121 (0.062) cm2V-1s-1 for holes (electrons), which increases to 1.01 (0.54) cm2V-1s-1 for that treated with muti-step slow annealing method. Moreover, the perovskite phototransistors exhibit a fast photoresponse speed of 78 μs. In general, this work focuses on the influence of annealing methods on perovskite phototransistor, instead of obtains best parameters of it. These findings prove that Multi-step annealing methods is feasible to prepared high performance based photodetector.

  7. NUMERICAL METHOD OF MIXED FINITE VOLUME-MODIFIED UPWIND FRACTIONAL STEP DIFFERENCE FOR THREE-DIMENSIONAL SEMICONDUCTOR DEVICE TRANSIENT BEHAVIOR PROBLEMS

    Institute of Scientific and Technical Information of China (English)

    Yirang YUAN; Qing YANG; Changfeng LI; Tongjun SUN

    2017-01-01

    Transient behavior of three-dimensional semiconductor device with heat conduction is described by a coupled mathematical system of four quasi-linear partial differential equations with initial-boundary value conditions.The electric potential is defined by an elliptic equation and it appears in the following three equations via the electric field intensity.The electron concentration and the hole concentration are determined by convection-dominated diffusion equations and the temperature is interpreted by a heat conduction equation.A mixed finite volume element approximation,keeping physical conservation law,is used to get numerical values of the electric potential and the accuracy is improved one order.Two concentrations and the heat conduction are computed by a fractional step method combined with second-order upwind differences.This method can overcome numerical oscillation,dispersion and decreases computational complexity.Then a three-dimensional problem is solved by computing three successive one-dimensional problems where the method of speedup is used and the computational work is greatly shortened.An optimal second-order error estimate in L2 norm is derived by using prior estimate theory and other special techniques of partial differential equations.This type of mass-conservative parallel method is important and is most valuable in numerical analysis and application of semiconductor device.

  8. Cardiovascular risk in rheumatoid arthritis: assessment, management and next steps

    Science.gov (United States)

    Zegkos, Thomas; Kitas, George; Dimitroulas, Theodoros

    2016-01-01

    Rheumatoid arthritis (RA) is associated with increased cardiovascular (CV) morbidity and mortality which cannot be fully explained by traditional CV risk factors; cumulative inflammatory burden and antirheumatic medication-related cardiotoxicity seem to be important contributors. Despite the acknowledgment and appreciation of CV disease burden in RA, optimal management of individuals with RA represents a challenging task which remains suboptimal. To address this need, the European League Against Rheumatism (EULAR) published recommendations suggesting the adaptation of traditional risk scores by using a multiplication factor of 1.5 if two of three specific criteria are fulfilled. Such guidance requires proper coordination of several medical specialties, including general practitioners, rheumatologists, cardiologists, exercise physiologists and psychologists to achieve a desirable result. Tight control of disease activity, management of traditional risk factors and lifestyle modification represent, amongst others, the most important steps in improving CV disease outcomes in RA patients. Rather than enumerating studies and guidelines, this review attempts to critically appraise current literature, highlighting future perspectives of CV risk management in RA. PMID:27247635

  9. Distributed Prognostics System Implementation on Wireless Embedded Devices

    Data.gov (United States)

    National Aeronautics and Space Administration — Distributed prognostics is the next step in the evolution of prognostic methodologies. It is an important enabling technology for the emerging Condition Based...

  10. When a Step Is Not a Step! Specificity Analysis of Five Physical Activity Monitors.

    Science.gov (United States)

    O'Connell, Sandra; ÓLaighin, Gearóid; Quinlan, Leo R

    2017-01-01

    Physical activity is an essential aspect of a healthy lifestyle for both physical and mental health states. As step count is one of the most utilized measures for quantifying physical activity it is important that activity-monitoring devices be both sensitive and specific in recording actual steps taken and disregard non-stepping body movements. The objective of this study was to assess the specificity of five activity monitors during a variety of prescribed non-stepping activities. Participants wore five activity monitors simultaneously for a variety of prescribed activities including deskwork, taking an elevator, taking a bus journey, automobile driving, washing and drying dishes; functional reaching task; indoor cycling; outdoor cycling; and indoor rowing. Each task was carried out for either a specific duration of time or over a specific distance. Activity monitors tested were the ActivPAL micro™, NL-2000™ pedometer, Withings Smart Activity Monitor Tracker (Pulse O2)™, Fitbit One™ and Jawbone UP™. Participants were video-recorded while carrying out the prescribed activities and the false positive step count registered on each activity monitor was obtained and compared to the video. All activity monitors registered a significant number of false positive steps per minute during one or more of the prescribed activities. The Withings™ activity performed best, registering a significant number of false positive steps per minute during the outdoor cycling activity only (P = 0.025). The Jawbone™ registered a significant number of false positive steps during the functional reaching task and while washing and drying dishes, which involved arm and hand movement (P positive steps during the cycling exercises (P positive steps were registered on the activity monitors during the non-stepping activities, the authors conclude that non-stepping physical activities can result in the false detection of steps. This can negatively affect the quantification of physical

  11. Improvement Performance of the Filling Step in Injection Mold through Vibration

    Directory of Open Access Journals (Sweden)

    Trejo-Hernández M.

    2012-10-01

    Full Text Available This paper shows the flow improvement in the filling step of the polymer injection process due to the polymer excitation though vibration. This process can be split up into three main steps: filling, pocking and cooling. Several mechanical and aesthetic properties of the finished product can be changed in the filling step. The objective of this investigation is to demonstrate the improvement in the filling mold under vibration without adding chemical products. To reach this result, an experimental mold was designed and manufactured in which a vibration device was coupled; it was possible to demonstrate the vibration advantage through this process. Moreover, a heuristic methodology was proposed for the experiment which shows an improvement in the filling process with frequencies close to 3 Hz.

  12. Patient preference and ease of use for different coagulation factor VIII reconstitution device scenarios: a cross-sectional survey in five European countries

    Directory of Open Access Journals (Sweden)

    Cimino E

    2014-12-01

    Full Text Available Ernesto Cimino,1 Silvia Linari,2 Mara Malerba,3 Susan Halimeh,4 Francesca Biondo,5 Martina Westfeld5 1Dipartimento Medicina Clinica e Sperimentale, Universita’ degli Studi di Napoli Federico II, Naples, Italy; 2Agenzia per l’ Emofilia, AOU Careggi di Firenze, Florence, Italy; 3Fondazione Cà Granda Ospedale Maggiore Policlinico, Centro Emofilia e Trombosi “A Bianchi Bonomi”, Milan, Italy; 4CRC Coagulation Research Centre GmbH, Duisburg, Germany; 5Pfizer Italia, Rome, Italy Introduction: Hemophilia A treatment involves replacing the deficient coagulation factor VIII. This process may involve multiple steps that might create a barrier to adherence. A new dual-chamber syringe (DCS; FuseNGo® was recently introduced with the aim of simplifying reconstitution. Aim: This study aimed to identify factors associated with adult patients’ preferences for different coagulation factor VIII reconstitution systems and to test ease of use and patient preference for the DCS. Methods: A cross-sectional survey of adults with hemophilia A in five European countries was conducted; a subset of subjects also participated in a practical testing session of the DCS. Results: Among the 299 survey participants, the device scenario requiring the least equipment and reconstitution steps (the DCS received a median preference rating of 71 out of 100 (0 being “the least desirable” and 100 “the most desirable” rating. This was significantly higher than the other scenarios (the next highest achieved a median of 50 points; P<0.001. Participants would be more likely to use this device prophylactically (P<0.001. Among the 98 participants who tested the DCS, 57% preferred this device over their current device, 26% preferred their current device, and 17% had no preference. The DCS was rated as easier to use than current treatment devices (median score 9/10 versus 7/10 for current treatment, P=0.001. Conclusion: The survey indicates that the prefilled DCS, Fuse

  13. The transient response of a quantum wave to an instantaneous potential step switching

    Energy Technology Data Exchange (ETDEWEB)

    Delgado, F [Departamento de Quimica-Fisica, Universidad del Pais Vasco, Apdo 644, 48080 Bilbao (Spain); Cruz, H [Departamento de Fisica Basica, Universidad de La Laguna (Spain); Muga, J G [Departamento de Quimica-Fisica, Universidad del Pais Vasco, Apdo 644, 48080 Bilbao (Spain)

    2002-12-06

    The transient response of a stationary state of a quantum particle in a step potential to an instantaneous change in the step height (a simplified model for a sudden bias switch in an electronic semiconductor device) is solved exactly by means of a semianalytical expression. The characteristic times for the transient process up to the new stationary state are identified. A comparison is made between the exact results and an approximate method.

  14. Medical Device Regulation: A Comparison of the United States and the European Union.

    Science.gov (United States)

    Maak, Travis G; Wylie, James D

    2016-08-01

    Medical device regulation is a controversial topic in both the United States and the European Union. Many physicians and innovators in the United States cite a restrictive US FDA regulatory process as the reason for earlier and more rapid clinical advances in Europe. The FDA approval process mandates that a device be proved efficacious compared with a control or be substantially equivalent to a predicate device, whereas the European Union approval process mandates that the device perform its intended function. Stringent, peer-reviewed safety data have not been reported. However, after recent high-profile device failures, political pressure in both the United States and the European Union has favored more restrictive approval processes. Substantial reforms of the European Union process within the next 5 to 10 years will result in a more stringent approach to device regulation, similar to that of the FDA. Changes in the FDA regulatory process have been suggested but are not imminent.

  15. One-step implementation of the Toffoli gate via quantum Zeno dynamics

    International Nuclear Information System (INIS)

    Shao Xiaoqiang; Wang Hongfu; Chen Li; Zhang Shou; Yeon, Kyu-Hwang

    2009-01-01

    Based on the quantum Zeno dynamics, we present a scheme for one-step implementation of a Toffoli gate via manipulating three rf superconducting quantum interference device (SQUID) qubits to resonantly interact with a superconducting cavity. The effects of decoherence such as spontaneous emission and the loss of cavity are also considered.

  16. Next generation solar energy. From fundamentals to applications

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    Within the International Conference between 12th and 14th December, 2011 in Erlangen (Federal Republic of Germany) the following lectures were presented: (1) The opto-electronic physics required to approach the Shockley-Queisser efficiency limit (E. Yablonovitch); (2) The Shockley-Queisser-limit and beyond (G.H. Bauer); (3) Designing composite nanomaterials for photovoltaic devices (B. Rech); (4) Light-Material interactions in energy conversion (H. Atwater); (5) Functional imaging of hybrid nanostructures - Visualizing mechanisms of solar energy utilization (L. Lauhon); (6) Are photosynthetic proteins suitable for PV applications (Y. Rosenwaks); (7) Detailed balance limit in photovoltaic systems (U. Rau); (8) Plasmonics and nanophotonics for next generation photovoltaics (E. Garnett); (9) Dispersion, wave propagation and efficiency analysis of nanowire solar cells (B. Witzigmann); (10) Application of nanostructures to next generation photovoltaics - Opportunities and challenges from an industrial research perspective (L. Tsakalakos); (11) Triplet states in organic and organometallic photovoltaic cells (K.S. Schanze); (12) New photoelectrode architectures (J.T. Hupp); (13) Dendrimers for optoelectronic and photovoltaic applications (P. Ceroni); (14) Photon management with luminescent materials (J. Goldschmidt); (15) Economical aspects of next generation solar cell technologies (W. Hoffmann); (16) Scalability in solar energy conversion - First-row transition metal-based chromophores for dye-sensitized solar cells (J. McCusker); (17) Designing organic materials for photovoltaic devices (A. Harriman); (18) Molecular photovoltaics - What can we learn from model studies (B. Albinsson); (19) Porphyrin-sensitised titanium dioxide solar cells (D. Officer); (20) Light-harvesting: Charge separation, and charge-transportation properties of novel materials for organic photovoltaics (H. Imahori); (21) Phthalocyanines for molecular photovoltaics (T. Torres); (22) Photophysics of

  17. Supporting study product use and accuracy in self-report in the iPrEx study: next step counseling and neutral assessment.

    Science.gov (United States)

    R Amico, K; McMahan, Vanessa; Goicochea, Pedro; Vargas, Lorena; Marcus, Julia L; Grant, Robert M; Liu, Albert

    2012-07-01

    The recent successes of biomedical HIV prevention approaches have sparked considerable debate over the scalability, feasibility, and acceptability of pre-exposure prophylaxis (PrEP) as a widespread prevention strategy for men who have sex with men and trans-gender. Anticipated difficulties with PrEP adherence and concerns about resources required to best support it have tempered enthusiasm of PrEP demonstration projects and roll-out. While no evidence-based approach for supporting PrEP use is presently available, a number of approaches have been developed in the context of double-blind, randomized, placebo-controlled trials of PrEP that can provide guidance in moving forward with real world support of open label PrEP use. We present the development, implementation and evaluation of feasibility and acceptability of next-step counseling (NSC) and neutral assessment (NA), the adherence support and promotion of accurate reporting approaches used in the late phases of the iPrEx study. Evaluation of the approach from the perspective of implementers of over 15,000 NSC sessions in seven different countries with almost 2,000 iPrEx participants provided support for NSC, its brevity (averaging ~14 min per follow-up session) and overall acceptability and feasibility. NA also was generally well supported, with a majority of study staff believing this approach was feasible and acceptable; however, lower acceptability for certain aspects of NA was noted amongst staff reporting NA was different from their previous interview approach. Quantitative and qualitative data gathered from implementers were used to make modifications for supporting PrEP use in the open-label extension of iPrEx.

  18. Effects of walking speed on the step-by-step control of step width.

    Science.gov (United States)

    Stimpson, Katy H; Heitkamp, Lauren N; Horne, Joscelyn S; Dean, Jesse C

    2018-02-08

    Young, healthy adults walking at typical preferred speeds use step-by-step adjustments of step width to appropriately redirect their center of mass motion and ensure mediolateral stability. However, it is presently unclear whether this control strategy is retained when walking at the slower speeds preferred by many clinical populations. We investigated whether the typical stabilization strategy is influenced by walking speed. Twelve young, neurologically intact participants walked on a treadmill at a range of prescribed speeds (0.2-1.2 m/s). The mediolateral stabilization strategy was quantified as the proportion of step width variance predicted by the mechanical state of the pelvis throughout a step (calculated as R 2 magnitude from a multiple linear regression). Our ability to accurately predict the upcoming step width increased over the course of a step. The strength of the relationship between step width and pelvis mechanics at the start of a step was reduced at slower speeds. However, these speed-dependent differences largely disappeared by the end of a step, other than at the slowest walking speed (0.2 m/s). These results suggest that mechanics-dependent adjustments in step width are a consistent component of healthy gait across speeds and contexts. However, slower walking speeds may ease this control by allowing mediolateral repositioning of the swing leg to occur later in a step, thus encouraging slower walking among clinical populations with limited sensorimotor control. Published by Elsevier Ltd.

  19. Control Software for Piezo Stepping Actuators

    Science.gov (United States)

    Shields, Joel F.

    2013-01-01

    A control system has been developed for the Space Interferometer Mission (SIM) piezo stepping actuator. Piezo stepping actuators are novel because they offer extreme dynamic range (centimeter stroke with nanometer resolution) with power, thermal, mass, and volume advantages over existing motorized actuation technology. These advantages come with the added benefit of greatly reduced complexity in the support electronics. The piezo stepping actuator consists of three fully redundant sets of piezoelectric transducers (PZTs), two sets of brake PZTs, and one set of extension PZTs. These PZTs are used to grasp and move a runner attached to the optic to be moved. By proper cycling of the two brake and extension PZTs, both forward and backward moves of the runner can be achieved. Each brake can be configured for either a power-on or power-off state. For SIM, the brakes and gate of the mechanism are configured in such a manner that, at the end of the step, the actuator is in a parked or power-off state. The control software uses asynchronous sampling of an optical encoder to monitor the position of the runner. These samples are timed to coincide with the end of the previous move, which may consist of a variable number of steps. This sampling technique linearizes the device by avoiding input saturation of the actuator and makes latencies of the plant vanish. The software also estimates, in real time, the scale factor of the device and a disturbance caused by cycling of the brakes. These estimates are used to actively cancel the brake disturbance. The control system also includes feedback and feedforward elements that regulate the position of the runner to a given reference position. Convergence time for smalland medium-sized reference positions (less than 200 microns) to within 10 nanometers can be achieved in under 10 seconds. Convergence times for large moves (greater than 1 millimeter) are limited by the step rate.

  20. Wearable Fall Detector using Integrated Sensors and Energy Devices

    OpenAIRE

    Sungmook Jung; Seungki Hong; Jaemin Kim; Sangkyu Lee; Taeghwan Hyeon; Minbaek Lee; Dae-Hyeong Kim

    2015-01-01

    Wearable devices have attracted great attentions as next-generation electronic devices. For the comfortable, portable, and easy-to-use system platform in wearable electronics, a key requirement is to replace conventional bulky and rigid energy devices into thin and deformable ones accompanying the capability of long-term energy supply. Here, we demonstrate a wearable fall detection system composed of a wristband-type deformable triboelectric generator and lithium ion battery in conjunction wi...

  1. Biofabrication to build the biology-device interface

    International Nuclear Information System (INIS)

    Liu Yi; Kim, Eunkyoung; Culver, James N; Bentley, William E; Payne, Gregory F; Ghodssi, Reza; Rubloff, Gary W

    2010-01-01

    The last century witnessed spectacular advances in both microelectronics and biotechnology yet there was little synergy between the two. A challenge to their integration is that biological and electronic systems are constructed using divergent fabrication paradigms. Biology fabricates bottom-up with labile components, while microelectronic devices are fabricated top-down using methods that are 'bio-incompatible'. Biofabrication-the use of biological materials and mechanisms for construction-offers the opportunity to span these fabrication paradigms by providing convergent approaches for building the bio-device interface. Integral to biofabrication are stimuli-responsive materials (e.g. film-forming polysaccharides) that allow directed assembly under near physiological conditions in response to device-imposed signals. Biomolecular engineering, through recombinant technology, allows biological components to be endowed with information for assembly (e.g. encoded in a protein's amino acid sequence). Finally, self-assembly and enzymatic assembly provide the mechanisms for construction over a hierarchy of length scales. Here, we review recent advances in the use of biofabrication to build the bio-device interface. We anticipate that the biofabrication toolbox will expand over the next decade as more researchers enlist the unique construction capabilities of biology. Further, we look forward to observing the application of this toolbox to create devices that can better diagnose disease, detect pathogens and discover drugs. Finally, we expect that biofabrication will enable the effective interfacing of biology with electronics to create implantable devices for personalized and regenerative medicine. (topical review)

  2. Mobile Genome Express (MGE: A comprehensive automatic genetic analyses pipeline with a mobile device.

    Directory of Open Access Journals (Sweden)

    Jun-Hee Yoon

    Full Text Available The development of next-generation sequencing (NGS technology allows to sequence whole exomes or genome. However, data analysis is still the biggest bottleneck for its wide implementation. Most laboratories still depend on manual procedures for data handling and analyses, which translates into a delay and decreased efficiency in the delivery of NGS results to doctors and patients. Thus, there is high demand for developing an automatic and an easy-to-use NGS data analyses system. We developed comprehensive, automatic genetic analyses controller named Mobile Genome Express (MGE that works in smartphones or other mobile devices. MGE can handle all the steps for genetic analyses, such as: sample information submission, sequencing run quality check from the sequencer, secured data transfer and results review. We sequenced an Actrometrix control DNA containing multiple proven human mutations using a targeted sequencing panel, and the whole analysis was managed by MGE, and its data reviewing program called ELECTRO. All steps were processed automatically except for the final sequencing review procedure with ELECTRO to confirm mutations. The data analysis process was completed within several hours. We confirmed the mutations that we have identified were consistent with our previous results obtained by using multi-step, manual pipelines.

  3. Mobile Genome Express (MGE): A comprehensive automatic genetic analyses pipeline with a mobile device.

    Science.gov (United States)

    Yoon, Jun-Hee; Kim, Thomas W; Mendez, Pedro; Jablons, David M; Kim, Il-Jin

    2017-01-01

    The development of next-generation sequencing (NGS) technology allows to sequence whole exomes or genome. However, data analysis is still the biggest bottleneck for its wide implementation. Most laboratories still depend on manual procedures for data handling and analyses, which translates into a delay and decreased efficiency in the delivery of NGS results to doctors and patients. Thus, there is high demand for developing an automatic and an easy-to-use NGS data analyses system. We developed comprehensive, automatic genetic analyses controller named Mobile Genome Express (MGE) that works in smartphones or other mobile devices. MGE can handle all the steps for genetic analyses, such as: sample information submission, sequencing run quality check from the sequencer, secured data transfer and results review. We sequenced an Actrometrix control DNA containing multiple proven human mutations using a targeted sequencing panel, and the whole analysis was managed by MGE, and its data reviewing program called ELECTRO. All steps were processed automatically except for the final sequencing review procedure with ELECTRO to confirm mutations. The data analysis process was completed within several hours. We confirmed the mutations that we have identified were consistent with our previous results obtained by using multi-step, manual pipelines.

  4. Progress in ICRH and lower hybrid launcher development

    International Nuclear Information System (INIS)

    Kaye, A.S.

    1993-01-01

    Radio frequency methods of heating and non-inductive current drive have become well established and are likely to be part of any next-step Tokamak programme. The present state of development of antennae for ion cyclotron heating and recent developments to enhance the effectiveness of fast wave current drive systems are reviewed. The performance achieved by present systems enables the provision of an ICRH system for next step devices within the existing technology limits. The main Lower Hybrid current drive systems are also reviewed. Present operating limits suggest that the design power density at the grill in large multijunction launchers must be somewhat reduced due to peaking of the electric field. The resulting launcher for a next step machine based on present technology is a large and highly complex device. Development of recent proposals such as the rod array or the hyperguide, in parallel with necessary improvements in the current drive efficiency, would make Lower Hybrid a more attractive method of non-inductive current drive for next step machines. (Author)

  5. Topological interface states and effects for next generation of innovative devices

    International Nuclear Information System (INIS)

    Kantser, Valeriu; Carlig, Sergiu

    2013-01-01

    Topological insulators (TI) have opened a gateway to search new quantum electronic phase of the condensed matter as well as to pave new platform of modern technology. This stems mainly on their unique surface states that are protected by time-reversal symmetry, show the Dirac cones connecting the inverted conduction and valence bands and exhibit unique spin-momentum locking property. Increasing the surface state contribution in proportion to the bulk of material is critical to investigate the surface states and for future innovative device applications. The way to achieve this is to configure topological insulators into nanostructures, which at the same time in combination with others materials significantly enlarge the variety of new states and phenomena. This article reviews the recent progress made in topological insulator nano heterostructures electronic states investigation. The state of art of different new scenario of engineering topologically interface states in the TI heterostructures are revealed, in particular by using polarization fields and antiferromagnetic ordering. Some of new proposals for innovative electronic devices are discussed. (authors)

  6. Evaluating the Consistency of Current Mainstream Wearable Devices in Health Monitoring: A Comparison Under Free-Living Conditions.

    Science.gov (United States)

    Wen, Dong; Zhang, Xingting; Liu, Xingyu; Lei, Jianbo

    2017-03-07

    Wearable devices are gaining increasing market attention; however, the monitoring accuracy and consistency of the devices remains unknown. The purpose of this study was to assess the consistency of the monitoring measurements of the latest wearable devices in the state of normal activities to provide advice to the industry and support to consumers in making purchasing choices. Ten pieces of representative wearable devices (2 smart watches, 4 smart bracelets of Chinese brands or foreign brands, and 4 mobile phone apps) were selected, and 5 subjects were employed to simultaneously use all the devices and the apps. From these devices, intact health monitoring data were acquired for 5 consecutive days and analyzed on the degree of differences and the relationships of the monitoring measurements ​​by the different devices. The daily measurements by the different devices fluctuated greatly, and the coefficient of variation (CV) fluctuated in the range of 2-38% for the number of steps, 5-30% for distance, 19-112% for activity duration, .1-17% for total energy expenditure (EE), 22-100% for activity EE, 2-44% for sleep duration, and 35-117% for deep sleep duration. After integrating the measurement data of 25 days among the devices, the measurements of the number of steps (intraclass correlation coefficient, ICC=.89) and distance (ICC=.84) displayed excellent consistencies, followed by those of activity duration (ICC=.59) and the total EE (ICC=.59) and activity EE (ICC=.57). However, the measurements for sleep duration (ICC=.30) and deep sleep duration (ICC=.27) were poor. For most devices, there was a strong correlation between the number of steps and distance measurements (R 2 >.95), and for some devices, there was a strong correlation between activity duration measurements and EE measurements (R 2 >.7). A strong correlation was observed in the measurements of steps, distance and EE from smart watches and mobile phones of the same brand, Apple or Samsung (r>.88

  7. Three-dimensional electrokinetic tweezing: device design, modeling, and control algorithms

    International Nuclear Information System (INIS)

    Probst, Roland; Shapiro, Benjamin

    2011-01-01

    We show how to extend electrokinetic tweezing (which can manipulate any visible particles and has more favorable force scaling than optical actuation enabling manipulation of nanoscale objects to nanoscopic precision) from two-dimensional control to the third dimension (3D). A novel and practical multi-layer device is presented that can create both planar and vertical flow and electric field modes. Feedback control algorithms are developed and demonstrated in realistic simulations to show 3D manipulation of one and two particles independently. The design and control results presented here are the essential next step to go from current 2D manipulation capabilities to an experimental demonstration of nano-precise 3D electrokinetic tweezing in a microfluidic system. Doing so requires integration with vision-based nano-precise 3D particle imaging, a capability that has been shown in the literature and which we are now combining with the 3D actuation and control methods demonstrated here. (technical note)

  8. Characteristics of the Current-Controlled Phase Transition of VO2 Microwires for Hybrid Optoelectronic Devices

    Directory of Open Access Journals (Sweden)

    Arash Joushaghani

    2015-08-01

    Full Text Available The optical and electrical characteristics of the insulator-metal phase transition of vanadium dioxide (VO2 enable the realization of power-efficient, miniaturized hybrid optoelectronic devices. This work studies the current-controlled, two-step insulator-metal phase transition of VO2 in varying microwire geometries. Geometry-dependent scaling trends extracted from current-voltage measurements show that the first step induced by carrier injection is delocalized over the microwire, while the second, thermally-induced step is localized to a filament about 1 to 2 μm wide for 100 nm-thick sputtered VO2 films on SiO2. These effects are confirmed by direct infrared imaging, which also measures the change in optical absorption in the two steps. The difference between the threshold currents of the two steps increases as the microwires are narrowed. Micron- and sub-micron-wide VO2 structures can be used to separate the two phase transition steps in photonic and electronic devices.

  9. Final report for project "Next-Generation Semiconductors for Solar Photoelectrolysis"

    Energy Technology Data Exchange (ETDEWEB)

    Khalifah, Peter [Stony Brook Univ., NY (United States)

    2016-09-15

    In this paper, effective methods have been developed for preparing high-quality LaTiO2N films on conductive La5Ti5O17 substrates that can serve as photoanodes for photoelectrochemical water oxidation. One paper has been written by the post-doc who completed this comprehensive, interdisciplinary study, and it is presently being finalized for submission. Our approach to this system integrates expertise that we have developed in single crystal growth, thin film growth, and thin film post-processing. Through this work, LTON films have been fully optimized for light harvesting, as their band gap is optimally matched with the incident solar spectrum and the film thicknesses have been optimized based on the absolute absorption coefficients that we have measured for this system. The next step is to optimize the co-catalyst functionalization and the solution conditions to maximize the catalytic activity for water oxidation. Since the preliminary tests described here were done without a water oxidation co-catalyst, and since good water oxidation catalysts have previously been identified based on studies of powder samples, this next step is highly likely to be successful.

  10. Disease-responsive drug delivery: the next generation of smart delivery devices.

    Science.gov (United States)

    Wanakule, Prinda; Roy, Krishnendu

    2012-01-01

    With the advent of highly potent and cytotoxic drugs, it is increasingly critical that they be targeted and released only in cells of diseased tissues, while sparing physiologically normal neighbors. Simple ligand-based targeting of drug carriers, although promising, cannot always provide the required specificity to achieve this since often normal cells also express significant levels of the targeted receptors. Therefore, stimuli-responsive delivery systems are being explored to allow drug release from nano- and microcarriers and implantable devices, primarily in the presence of physiological or disease-specific pathophysiological signals. Designing smart biomaterials that respond to temperature or pH changes, protein and ligand binding, disease-specific degradation, e.g. enzymatic cleavage, has become an integral part of this approach. These strategies are used in combination with nano- and microparticle systems to improve delivery efficiency through several routes of administration, and with injectable or implantable systems for long term controlled release. This review focuses on recent developments in stimuli-responsive systems, their physicochemical properties, release profiles, efficacy, safety and biocompatibility, as well as future perspectives.

  11. When a Step Is Not a Step! Specificity Analysis of Five Physical Activity Monitors.

    Directory of Open Access Journals (Sweden)

    Sandra O'Connell

    Full Text Available Physical activity is an essential aspect of a healthy lifestyle for both physical and mental health states. As step count is one of the most utilized measures for quantifying physical activity it is important that activity-monitoring devices be both sensitive and specific in recording actual steps taken and disregard non-stepping body movements. The objective of this study was to assess the specificity of five activity monitors during a variety of prescribed non-stepping activities.Participants wore five activity monitors simultaneously for a variety of prescribed activities including deskwork, taking an elevator, taking a bus journey, automobile driving, washing and drying dishes; functional reaching task; indoor cycling; outdoor cycling; and indoor rowing. Each task was carried out for either a specific duration of time or over a specific distance. Activity monitors tested were the ActivPAL micro™, NL-2000™ pedometer, Withings Smart Activity Monitor Tracker (Pulse O2™, Fitbit One™ and Jawbone UP™. Participants were video-recorded while carrying out the prescribed activities and the false positive step count registered on each activity monitor was obtained and compared to the video.All activity monitors registered a significant number of false positive steps per minute during one or more of the prescribed activities. The Withings™ activity performed best, registering a significant number of false positive steps per minute during the outdoor cycling activity only (P = 0.025. The Jawbone™ registered a significant number of false positive steps during the functional reaching task and while washing and drying dishes, which involved arm and hand movement (P < 0.01 for both. The ActivPAL™ registered a significant number of false positive steps during the cycling exercises (P < 0.001 for both.As a number of false positive steps were registered on the activity monitors during the non-stepping activities, the authors conclude that non-stepping

  12. Challenges and opportunities for the next generation of photon regeneration experiments

    International Nuclear Information System (INIS)

    Ringwald, Andreas

    2010-03-01

    Photon regeneration experiments searching for signatures of oscillations of photons into hypothetical very weakly interacting ultra-light particles, such as axions, axion-like and hiddensector particles, have improved their sensitivity considerably in recent years. Important progress in laser and detector technology as well as recycling of available magnets from accelerators may allow a big further step in sensitivity such that, for the first time, laser light shining through a wall experiments will explore territory in parameter space that has not been excluded yet by astrophysics and cosmology.We review these challenges and opportunities for the next generation experiments. (orig.)

  13. Medical device software: defining key terms.

    Science.gov (United States)

    Pashkov, Vitalii; Gutorova, Nataliya; Harkusha, Andrii

    one of the areas of significant growth in medical devices has been the role of software - as an integral component of a medical device, as a standalone device and more recently as applications on mobile devices. The risk related to a malfunction of the standalone software used within healthcare is in itself not a criterion for its qualification or not as a medical device. It is therefore, necessary to clarify some criteria for the qualification of stand-alone software as medical devices Materials and methods: Ukrainian, European Union, United States of America legislation, Guidelines developed by European Commission and Food and Drug Administration's, recommendations represented by international voluntary group and scientific works. This article is based on dialectical, comparative, analytic, synthetic and comprehensive research methods. the legal regulation of software which is used for medical purpose in Ukraine limited to one definition. In European Union and United States of America were developed and applying special guidelines that help developers, manufactures and end users to difference software on types standing on medical purpose criteria. Software becomes more and more incorporated into medical devices. Developers and manufacturers may not have initially appreciated potential risks to patients and users such situation could have dangerous results for patients or users. It is necessary to develop and adopt the legislation that will intend to define the criteria for the qualification of medical device software and the application of the classification criteria to such software, provide some illustrative examples and step by step recommendations to qualify software as medical device.

  14. AgMIP: Next Generation Models and Assessments

    Science.gov (United States)

    Rosenzweig, C.

    2014-12-01

    Next steps in developing next-generation crop models fall into several categories: significant improvements in simulation of important crop processes and responses to stress; extension from simplified crop models to complex cropping systems models; and scaling up from site-based models to landscape, national, continental, and global scales. Crop processes that require major leaps in understanding and simulation in order to narrow uncertainties around how crops will respond to changing atmospheric conditions include genetics; carbon, temperature, water, and nitrogen; ozone; and nutrition. The field of crop modeling has been built on a single crop-by-crop approach. It is now time to create a new paradigm, moving from 'crop' to 'cropping system.' A first step is to set up the simulation technology so that modelers can rapidly incorporate multiple crops within fields, and multiple crops over time. Then the response of these more complex cropping systems can be tested under different sustainable intensification management strategies utilizing the updated simulation environments. Model improvements for diseases, pests, and weeds include developing process-based models for important diseases, frameworks for coupling air-borne diseases to crop models, gathering significantly more data on crop impacts, and enabling the evaluation of pest management strategies. Most smallholder farming in the world involves integrated crop-livestock systems that cannot be represented by crop modeling alone. Thus, next-generation cropping system models need to include key linkages to livestock. Livestock linkages to be incorporated include growth and productivity models for grasslands and rangelands as well as the usual annual crops. There are several approaches for scaling up, including use of gridded models and development of simpler quasi-empirical models for landscape-scale analysis. On the assessment side, AgMIP is leading a community process for coordinated contributions to IPCC AR6

  15. Particle and impurity control in toroidal fusion devices

    International Nuclear Information System (INIS)

    Wootton, A.J.

    1986-01-01

    A review of working particle and impurity control techniques used in and proposed for magnetic fusion devices is presented. The requirements of both present-day machines and envisaged fusion reactors are considered. The various techniques which have been proposed are characterized by whether they affect sources, sinks, or fluxes; in many cases a particular method or device can appear in more than one category. Examples are drawn from published results. The solutions proposed for the large devices which will be operating during the next 5 years are discussed

  16. Next steps for a Green Economy Working Group in Kazakhstan. Notes from the Astana Green Economy Dialogue, 24-26 November 2011

    Energy Technology Data Exchange (ETDEWEB)

    Ospanova, Saule; Wilson, Emma; Bass, Steve

    2013-01-15

    In the Republic of Kazakhstan, national concerns over today’s economic, social and environmental challenges have translated into sustainable development policy and initiatives such as the Astana Green Bridge Initiative. The Government of Kazakhstan has developed the Green Bridge Partnership Programme (GBPP), with the support of international organizations, for possible adoption at the Rio+20 World Sustainable Development Conference in June 2012. This programme offers opportunities for 'greening' the economy, with a focus on aspirations for regional and international technology cooperation and finance. it also offers potential for enhancing public participation in decision-making, and harmonising policies and practices across European, Asian and Pacific regions. A range of other initiatives are also ongoing within Kazakhstan, and it is important for those promoting these initiatives to join forces and engage in dialogue. The Astana Green Economy Dialogue, held from 24th to 26th November 2011, organised by IIED and the Kazakhstan Ministry for the Environment and supported by the UK Foreign and Commonwealth Office (FCO) and the Organisation for Security and Co-operation in Europe (OSCE), brought together a range of stakeholders from government, civil society and industry to discuss the notion of the green economy and how it can be applied and developed in Kazakhstan. The dialogue had a particular focus on the energy sector given its relevance. Oil-producing states face a global challenge to play their part in establishing economic systems that reduce climate change and other environmental burdens, and to produce higher societal value from limited natural resources. This short report summarises the key observations and ideas discussed at the workshop, with recommendations for next steps and follow up. It is meant to provide a record of the discussions that took place at this dialogue and provides a foundation for further work.

  17. Nanophotonic Devices for Optical Interconnect

    DEFF Research Database (Denmark)

    Van Thourhout, D.; Spuesens, T.; Selvaraja, S.K.

    2010-01-01

    We review recent progress in nanophotonic devices for compact optical interconnect networks. We focus on microdisk-laser-based transmitters and discuss improved design and advanced functionality including all-optical wavelength conversion and flip-flops. Next we discuss the fabrication uniformity...... of the passive routing circuits and their thermal tuning. Finally, we discuss the performance of a wavelength selective detector....

  18. Step-by-step guide to building an inexpensive 3D printed motorized positioning stage for automated high-content screening microscopy.

    Science.gov (United States)

    Schneidereit, Dominik; Kraus, Larissa; Meier, Jochen C; Friedrich, Oliver; Gilbert, Daniel F

    2017-06-15

    High-content screening microscopy relies on automation infrastructure that is typically proprietary, non-customizable, costly and requires a high level of skill to use and maintain. The increasing availability of rapid prototyping technology makes it possible to quickly engineer alternatives to conventional automation infrastructure that are low-cost and user-friendly. Here, we describe a 3D printed inexpensive open source and scalable motorized positioning stage for automated high-content screening microscopy and provide detailed step-by-step instructions to re-building the device, including a comprehensive parts list, 3D design files in STEP (Standard for the Exchange of Product model data) and STL (Standard Tessellation Language) format, electronic circuits and wiring diagrams as well as software code. System assembly including 3D printing requires approx. 30h. The fully assembled device is light-weight (1.1kg), small (33×20×8cm) and extremely low-cost (approx. EUR 250). We describe positioning characteristics of the stage, including spatial resolution, accuracy and repeatability, compare imaging data generated with our device to data obtained using a commercially available microplate reader, demonstrate its suitability to high-content microscopy in 96-well high-throughput screening format and validate its applicability to automated functional Cl - - and Ca 2+ -imaging with recombinant HEK293 cells as a model system. A time-lapse video of the stage during operation and as part of a custom assembled screening robot can be found at https://vimeo.com/158813199. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  19. Proceedings of US/Japan Workshop (97FT5-06) on High Heat Flux Components and Plasma Surface Interactions for Next Fusion Devices

    International Nuclear Information System (INIS)

    Nygren, Richard; Kureczko, Diana

    1998-10-01

    The 1997 US-Japan Workshop on High Heat Flux Components and Plasma Surface Interactions for Next Fusion Devices was held at the Warwick Regis Hotel in San Francisco, California, on December 8-11, 1997. There were 53 presentations as well as discussions on technical issues and on planning for future collaborations, and 35 researchers from japan and the US participated in the workshop. Over the last few years, with the strong emphasis in the US on technology for ITER, there has been less work done in the US fusion program on basic plasma materials interaction and this change in emphasis workshops. The program this year emphasized activities that were not carried out under the ITER program and a new element this year in the US program was planning and some analysis on liquid surface concepts for advanced plasma facing components. The program included a ceremony to honor Professor Yamashina, who was retiring this year and a special presentation on his career

  20. Environmental Information for the U.S. Next Generation Air Transportation System (NextGen)

    Science.gov (United States)

    Murray, J.; Miner, C.; Pace, D.; Minnis, P.; Mecikalski, J.; Feltz, W.; Johnson, D.; Iskendarian, H.; Haynes, J.

    2009-09-01

    It is estimated that weather is responsible for approximately 70% of all air traffic delays and cancellations in the United States. Annually, this produces an overall economic loss of nearly 40B. The FAA and NASA have determined that weather impacts and other environmental constraints on the U.S. National Airspace System (NAS) will increase to the point of system unsustainability unless the NAS is radically transformed. A Next Generation Air Transportation System (NextGen) is planned to accommodate the anticipated demand for increased system capacity and the super-density operations that this transformation will entail. The heart of the environmental information component that is being developed for NextGen will be a 4-dimensional data cube which will include a single authoritative source comprising probabilistic weather information for NextGen Air Traffic Management (ATM) systems. Aviation weather constraints and safety hazards typically comprise meso-scale, storm-scale and microscale observables that can significantly impact both terminal and enroute aviation operations. With these operational impacts in mind, functional and performance requirements for the NextGen weather system were established which require significant improvements in observation and forecasting capabilities. This will include satellite observations from geostationary and/or polar-orbiting hyperspectral sounders, multi-spectral imagers, lightning mappers, space weather monitors and other environmental observing systems. It will also require improved in situ and remotely sensed observations from ground-based and airborne systems. These observations will be used to better understand and to develop forecasting applications for convective weather, in-flight icing, turbulence, ceilings and visibility, volcanic ash, space weather and the environmental impacts of aviation. Cutting-edge collaborative research efforts and results from NASA, NOAA and the FAA which address these phenomena are summarized

  1. Concept for trusted personal devices in a mobile and networked environment

    NARCIS (Netherlands)

    Bormann, Frank C.; Manteau, Laurent; Linke, Andreas; Pailles, Jean C.; van Dijk, Johannes A.G.M.

    2006-01-01

    In this article we present a concept for Trusted Personal Devices, which are intended to be the common platform for the next generation of Smart Cards and other secure devices in mobile and networked environments. The concept is based on a classification of technical profiles for different potential

  2. Reconstruction of networks from one-step data by matching positions

    Science.gov (United States)

    Wu, Jianshe; Dang, Ni; Jiao, Yang

    2018-05-01

    It is a challenge in estimating the topology of a network from short time series data. In this paper, matching positions is developed to reconstruct the topology of a network from only one-step data. We consider a general network model of coupled agents, in which the phase transformation of each node is determined by its neighbors. From the phase transformation information from one step to the next, the connections of the tail vertices are reconstructed firstly by the matching positions. Removing the already reconstructed vertices, and repeatedly reconstructing the connections of tail vertices, the topology of the entire network is reconstructed. For sparse scale-free networks with more than ten thousands nodes, we almost obtain the actual topology using only the one-step data in simulations.

  3. Heat and mass transfer during the cryopreservation of a bioartificial liver device: a computational model.

    Science.gov (United States)

    Balasubramanian, Saravana K; Coger, Robin N

    2005-01-01

    Bioartificial liver devices (BALs) have proven to be an effective bridge to transplantation for cases of acute liver failure. Enabling the long-term storage of these devices using a method such as cryopreservation will ensure their easy off the shelf availability. To date, cryopreservation of liver cells has been attempted for both single cells and sandwich cultures. This study presents the potential of using computational modeling to help develop a cryopreservation protocol for storing the three dimensional BAL: Hepatassist. The focus is upon determining the thermal and concentration profiles as the BAL is cooled from 37 degrees C-100 degrees C, and is completed in two steps: a cryoprotectant loading step and a phase change step. The results indicate that, for the loading step, mass transfer controls the duration of the protocol, whereas for the phase change step, when mass transfer is assumed negligible, the latent heat released during freezing is the control factor. The cryoprotocol that is ultimately proposed considers time, cooling rate, and the temperature gradients that the cellular space is exposed to during cooling. To our knowledge, this study is the first reported effort toward designing an effective protocol for the cryopreservation of a three-dimensional BAL device.

  4. Coordination of push-off and collision determine the mechanical work of step-to-step transitions when isolated from human walking.

    Science.gov (United States)

    Soo, Caroline H; Donelan, J Maxwell

    2012-02-01

    In human walking, each transition to a new stance limb requires redirection of the center of mass (COM) velocity from one inverted pendulum arc to the next. While this can be accomplished with either negative collision work by the leading limb, positive push-off work by the trailing limb, or some combination of the two, physics-based models of step-to-step transitions predict that total positive work is minimized when the push-off and collision work are equal in magnitude. Here, we tested the importance of the coordination of push-off and collision work in determining transition work using ankle and knee joint braces to limit the ability of a leg to perform positive work on the body. To isolate transitions from other contributors to walking mechanics, participants were instructed to rock back and forth from one leg to the other, restricting motion to the sagittal plane and eliminating the need to swing the legs. We found that reduced push-off work increased the collision work required to complete the redirection of the COM velocity during each transition. A greater amount of total mechanical work was required when rocking departed from the predicted optimal coordination of step-to-step transitions, in which push-off and collision work are equal in magnitude. Our finding that transition work increases if one or both legs do not push-off with the optimal coordination may help explain the elevated metabolic cost of pathological gait irrespective of etiology. Copyright © 2011 Elsevier B.V. All rights reserved.

  5. Analysis and optimization of the TWINKLE factoring device

    NARCIS (Netherlands)

    Lenstra, A.K.; Shamir, A.; Preneel, B.

    2000-01-01

    We describe an enhanced version of the TWINKLE factoring device and analyse to what extent it can be expected to speed up the sieving step of the Quadratic Sieve and Number Field Sieve factoring al- gorithms. The bottom line of our analysis is that the TWINKLE-assisted factorization of 768-bit

  6. Wind energy in the next millennium and the next year

    International Nuclear Information System (INIS)

    Chabot, B.

    1999-01-01

    The rapid development of wind energy was once again confirmed in 1998 and everything points to the fact that this road will in the next century rapidly become the third channel of primary electricity production in the world, both in terms of annual sales and contribution of energy. In particular, a scenario for the development, of wind energy in the coming century is proposed, taking as model and minimum objective the historical development of success of wind energy should prove perfectly feasible, it is difficult to foresee in the short term the actual impact of the liberalization of electricity markets on existing inducements in favour of wind energy and even more difficult to estimate the effectiveness of new inducements more in line with this liberalization process. These difficulties may be overcome by selecting - for the long term scenario - a starting point within the next decade which is in line with the best market studies currently available and by constructing the model for variations in operational stock world-wide on the basis of a Rayleigh distribution, adjusted for the market conditions defined in the short term, in order that the future contributions defined in the short term, in order that the future contribution of wind energy might come to equal that of hydro-electricity before the end of the next century. (author)

  7. A novel device for studying weight supported, quadrupedal overground locomotion in spinal cord injured rats.

    Science.gov (United States)

    Hamlin, Marvin; Traughber, Terence; Reinkensmeyer, David J; de Leon, Ray D

    2015-05-15

    Providing weight support facilitates locomotion in spinal cord injured animals. To control weight support, robotic systems have been developed for treadmill stepping and more recently for overground walking. We developed a novel device, the body weight supported ambulatory rodent trainer (i.e. BART). It has a small pneumatic cylinder that moves along a linear track above the rat. When air is supplied to the cylinder, the rats are lifted as they perform overground walking. We tested the BART device in rats that received a moderate spinal cord contusion injury and in normal rats. Locomotor training with the BART device was not performed. All of the rats learned to walk in the BART device. In the contused rats, significantly greater paw dragging and dorsal stepping occurred in the hindlimbs compared to normal. Providing weight support significantly raised hip position and significantly reduced locomotor deficits. Hindlimb stepping was tightly coupled to forelimb stepping but only when the contused rats stepped without weight support. Three weeks after the contused rats received a complete spinal cord transection, significantly fewer hindlimb steps were performed. Relative to rodent robotic systems, the BART device is a simpler system for studying overground locomotion. The BART device lacks sophisticated control and sensing capability, but it can be assembled relatively easily and cheaply. These findings suggest that the BART device is a useful tool for assessing quadrupedal, overground locomotion which is a more natural form of locomotion relative to treadmill locomotion. Published by Elsevier B.V.

  8. Medical device market in China.

    Science.gov (United States)

    Boyer, Philip; Morshed, Bashir I; Mussivand, Tofy

    2015-06-01

    With China's growing old-age population and economic presence on the international stage, it has become important to evaluate its domestic and foreign market contribution to medical devices. Medical devices are instruments or apparatuses used in the prevention, rehabilitation, treatment, or knowledge generation with respect to disease or other abnormal conditions. This article provides information drawn from recent publications to describe the current state of the Chinese domestic market for medical devices and to define opportunities for foreign investment potential therein. Recent healthcare reforms implemented to meet rising demand due to an aging and migrating population are having a positive effect on market growth-a global market with a projected growth of 15% per year over the next decade. Copyright © 2015 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

  9. Towards self-assembled devices, a carbon nanotube approach

    OpenAIRE

    Del Rio Castillo, Antonio Esau

    2012-01-01

    2010/2011 In the last decade the nanostructured carbon materials, especially single walled carbon nanotubes (SWNTs), had emerged as probable substitutes for Silicon in the next generation of electronic devices. This is due to their unique physic and chemical properties. Likewise, scientists all around the world have made a huge effort to introduce carbon materials into the market. Despite this effort, commercial application for carbon nanotubes in electronic devices has not yet been achiev...

  10. Technical challenges in the construction of the steady-state stellarator Wendelstein 7-X

    NARCIS (Netherlands)

    Bosch, H. S.; R C Wolf,; Andreeva, T.; Baldzuhn, J.; Birus, D.; Bluhm, T.; Brauer, T.; Braune, H.; Bykov, V.; Cardella, A.; Durodie, F.; Endler, M.; Erckmann, V.; Gantenbein, G.; Hartmann, D.; Hathiramani, D.; Heimann, P.; Heinemann, B.; Hennig, C.; Hirsch, M.; Holtum, D.; Jagielski, J.; Jelonnek, J.; Kasparek, W.; Klinger, T.; Konig, R.; Kornejew, P.; Kroiss, H.; Krom, J. G.; Kuhner, G.; Laqua, H.; Laqua, H. P.; Lechte, C.; Lewerentz, M.; Maier, J.; McNeely, P.; Messiaen, A.; Michel, G.; Ongena, J.; Peacock, A.; Pedersen, T. S.; Riedl, R.; Riemann, H.; Rong, P.; Rust, N.; Schacht, J.; Schauer, F.; Schroeder, R.; Schweer, B.; Spring, A.; Stabler, A.; Thumm, M.; Turkin, Y.; Wegener, L.; Werner, A.; Zhang, D.; Zilker, M.; Akijama, T.; Alzbutas, R.; Ascasibar, E.; Balden, M.; Banduch, M.; Baylard, C.; Behr, W.; Beidler, C.; Benndorf, A.; Bergmann, T.; Biedermann, C.; Bieg, B.; Biel, W.; Borchardt, M.; Borowitz, G.; Borsuk, V.; Bozhenkov, S.; Brakel, R.; Brand, H.; Brown, T.; Brucker, B.; Burhenn, R.; Buscher, K. P.; Caldwell-Nichols, C.; Cappa, A.; Cardella, A.; Carls, A.; Carvalho, P.; Ciupinski, L.; Cole, M.; Collienne, J.; Czarnecka, A.; Czymek, G.; Dammertz, G.; Dhard, C. P.; Davydenko, V. I.; Dinklage, A.; Drevlak, M.; Drotziger, S.; Dudek, A.; Dumortier, P.; Dundulis, G.; von Eeten, P.; Egorov, K.; Estrada, T.; Faugel, H.; Fellinger, J.; Feng, Y.; Fernandes, H.; Fietz, W. H.; Figacz, W.; Fischer, F.; Fontdecaba, J.; Freund, A.; Funaba, T.; Funfgelder, H.; Galkowski, A.; Gates, D.; Giannone, L.; Regana, J. M. G.; Geiger, J.; Geissler, S.; Greuner, H.; Grahl, M.; Gross, S.; Grosman, A.; Grote, H.; Grulke, O.; R. Jaspers,; Szabo, V.

    2013-01-01

    The next step in the Wendelstein stellarator line is the large superconducting device Wendelstein 7-X, currently under construction in Greifswald, Germany. Steady-state operation is an intrinsic feature of stellarators, and one key element of the Wendelstein 7-X mission is to demonstrate

  11. TumorNext-Lynch-MMR: a comprehensive next generation sequencing assay for the detection of germline and somatic mutations in genes associated with mismatch repair deficiency and Lynch syndrome.

    Science.gov (United States)

    Gray, Phillip N; Tsai, Pei; Chen, Daniel; Wu, Sitao; Hoo, Jayne; Mu, Wenbo; Li, Bing; Vuong, Huy; Lu, Hsiao-Mei; Batth, Navanjot; Willett, Sara; Uyeda, Lisa; Shah, Swati; Gau, Chia-Ling; Umali, Monalyn; Espenschied, Carin; Janicek, Mike; Brown, Sandra; Margileth, David; Dobrea, Lavinia; Wagman, Lawrence; Rana, Huma; Hall, Michael J; Ross, Theodora; Terdiman, Jonathan; Cullinane, Carey; Ries, Savita; Totten, Ellen; Elliott, Aaron M

    2018-04-17

    The current algorithm for Lynch syndrome diagnosis is highly complex with multiple steps which can result in an extended time to diagnosis while depleting precious tumor specimens. Here we describe the analytical validation of a custom probe-based NGS tumor panel, TumorNext-Lynch-MMR, which generates a comprehensive genetic profile of both germline and somatic mutations that can accelerate and streamline the time to diagnosis and preserve specimen. TumorNext-Lynch-MMR can detect single nucleotide variants, small insertions and deletions in 39 genes that are frequently mutated in Lynch syndrome and colorectal cancer. Moreover, the panel provides microsatellite instability status and detects loss of heterozygosity in the five Lynch genes; MSH2 , MSH6 , MLH1 , PMS2 and EPCAM . Clinical cases are described that highlight the assays ability to differentiate between somatic and germline mutations, precisely classify variants and resolve discordant cases.

  12. Fiscal 2000 survey report on the survey of trends of quantum beam process technologies for development of high-speed large-capacity digital electronic information devices; 2000 nendo kosoku daiyoryo digital denshi joho device kaihatsu no tame no ryoshi beam process technology no doko chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    The effort clarifies the tasks and problems of the next-generation WDM (wavelength division multiplexing) device, the tasks and problems of domestic information digital devices, and the characteristics, and matters wanting further development, of quantum beam technologies that are to contribute to the development of the said devices. In concrete terms, quantum process technologies involving the ultralow energy ion beam, gas cluster ion beam, electron beam, laser beam, radiation, and the like, are to be studied and developed as device processes, and the product of the effort will be utilized for accelerating the currently difficult development of the semiconductor laser diode, high-speed photoelectric conversion diode, optical circuit device, and the next-generation plastic liquid crystal display device. That is to say, process technologies for a high-speed undamaged compound semiconductor device, high-precision optical circuit device, and a totally plastic liquid crystal display device will be established, and verified as valid. Furthermore, novel digital devices will be developed. In this research and development work, manufacturing process technologies will also be established, which as practical technologies will clear the rigorous goals that the industry demand for process stability, process yield, process amount, and the like. (NEDO)

  13. Low-temperature process steps for realization of non-volatile memory devices

    NARCIS (Netherlands)

    Brunets, I.; Boogaard, A.; Aarnink, Antonius A.I.; Kovalgin, Alexeij Y.; Wolters, Robertus A.M.; Holleman, J.; Schmitz, Jurriaan

    2007-01-01

    In this work, the low-temperature process steps required for the realization of nano-crystal non-volatile memory cells are discussed. An amorphous silicon film, crystallized using a diode pumped solid state green laser irradiating at 532 nm, is proposed as an active layer. The deposition of the

  14. Reliability and availability assessments for the next European Torus

    International Nuclear Information System (INIS)

    Bunde, R.

    1988-01-01

    To achieve its targets in reasonable time, the Next European Torus (NET) must be operated with considerable reliability and availability (R and A). Therefore, failure modes, effects, and criticality analysis (FMECA) of the overall plant and of its major components is already being performed as the design evolves. The present status of the R and A work is described in four steps: First, the R and A targets envisaged for the NET operation are discussed. Then an FMECA covering the overall plant is described, and a more detailed FMECA of major components is presented concerning the toroidal field coil systeml plasma heating systems; protection, instrumentation, and control systems; first wall and blanket, as well as the cooling system. Finally, the R and A results are compared with the targets, and measures for improvements are given

  15. Soft robotic devices for hand rehabilitation and assistance: a narrative review.

    Science.gov (United States)

    Chu, Chia-Ye; Patterson, Rita M

    2018-02-17

    The debilitating effects on hand function from a number of a neurologic disorders has given rise to the development of rehabilitative robotic devices aimed at restoring hand function in these patients. To combat the shortcomings of previous traditional robotics, soft robotics are rapidly emerging as an alternative due to their inherent safety, less complex designs, and increased potential for portability and efficacy. While several groups have begun designing devices, there are few devices that have progressed enough to provide clinical evidence of their design's therapeutic abilities. Therefore, a global review of devices that have been previously attempted could facilitate the development of new and improved devices in the next step towards obtaining clinical proof of the rehabilitative effects of soft robotics in hand dysfunction. A literature search was performed in SportDiscus, Pubmed, Scopus, and Web of Science for articles related to the design of soft robotic devices for hand rehabilitation. A framework of the key design elements of the devices was developed to ease the comparison of the various approaches to building them. This framework includes an analysis of the trends in portability, safety features, user intent detection methods, actuation systems, total DOF, number of independent actuators, device weight, evaluation metrics, and modes of rehabilitation. In this study, a total of 62 articles representing 44 unique devices were identified and summarized according to the framework we developed to compare different design aspects. By far, the most common type of device was that which used a pneumatic actuator to guide finger flexion/extension. However, the remainder of our framework elements yielded more heterogeneous results. Consequently, those results are summarized and the advantages and disadvantages of many design choices as well as their rationales were highlighted. The past 3 years has seen a rapid increase in the development of soft robotic

  16. PhysioDroid: combining wearable health sensors and mobile devices for a ubiquitous, continuous, and personal monitoring.

    Science.gov (United States)

    Banos, Oresti; Villalonga, Claudia; Damas, Miguel; Gloesekoetter, Peter; Pomares, Hector; Rojas, Ignacio

    2014-01-01

    Technological advances on the development of mobile devices, medical sensors, and wireless communication systems support a new generation of unobtrusive, portable, and ubiquitous health monitoring systems for continuous patient assessment and more personalized health care. There exist a growing number of mobile apps in the health domain; however, little contribution has been specifically provided, so far, to operate this kind of apps with wearable physiological sensors. The PhysioDroid, presented in this paper, provides a personalized means to remotely monitor and evaluate users' conditions. The PhysioDroid system provides ubiquitous and continuous vital signs analysis, such as electrocardiogram, heart rate, respiration rate, skin temperature, and body motion, intended to help empower patients and improve clinical understanding. The PhysioDroid is composed of a wearable monitoring device and an Android app providing gathering, storage, and processing features for the physiological sensor data. The versatility of the developed app allows its use for both average users and specialists, and the reduced cost of the PhysioDroid puts it at the reach of most people. Two exemplary use cases for health assessment and sports training are presented to illustrate the capabilities of the PhysioDroid. Next technical steps include generalization to other mobile platforms and health monitoring devices.

  17. Precision medicine for cancer with next-generation functional diagnostics.

    Science.gov (United States)

    Friedman, Adam A; Letai, Anthony; Fisher, David E; Flaherty, Keith T

    2015-12-01

    Precision medicine is about matching the right drugs to the right patients. Although this approach is technology agnostic, in cancer there is a tendency to make precision medicine synonymous with genomics. However, genome-based cancer therapeutic matching is limited by incomplete biological understanding of the relationship between phenotype and cancer genotype. This limitation can be addressed by functional testing of live patient tumour cells exposed to potential therapies. Recently, several 'next-generation' functional diagnostic technologies have been reported, including novel methods for tumour manipulation, molecularly precise assays of tumour responses and device-based in situ approaches; these address the limitations of the older generation of chemosensitivity tests. The promise of these new technologies suggests a future diagnostic strategy that integrates functional testing with next-generation sequencing and immunoprofiling to precisely match combination therapies to individual cancer patients.

  18. Evaluation of an Electrostatic Dust Removal System with Potential Application in Next-Step Fusion Devices

    International Nuclear Information System (INIS)

    Friesen, F.Q.L.; John, B.; Skinner, C.H.; Roquemore, A.L.; Calle, C.I.

    2011-01-01

    The ability to manage inventories of carbon, tritium, and high-Z elements in fusion plasmas depends on means for effective dust removal. A dust conveyor, based on a moving electrostatic potential well, was tested with particles of tungsten, carbon, glass and sand. A digital microscope imaged a representative portion of the conveyor, and dust particle size and volume distributions were derived before and after operation. About 10 mm3 volume of carbon and tungsten particles were moved in under 5 seconds. The highest driving amplitude tested of 3 kV was the most effective. The optimal driving frequency was 210 Hz (maximum tested) for tungsten particles, decreasing to below 60 Hz for the larger sand particles. Measurements of particle size and volume distributions after 10 and 100 cycles show the breaking apart of agglomerated carbon, and the change in particle distribution over short timescales (<1 s).

  19. Different Device Architectures for Bulk-Heterojunction Solar Cells

    Directory of Open Access Journals (Sweden)

    Getachew Adam

    2016-08-01

    Full Text Available We report different solar cell designs which allow a simple electrical connection of subsequent devices deposited on the same substrate. By arranging so-called standard and inverted solar-cell architectures next to each other, a serial connection of the two devices can easily be realized by a single compound electrode. In this work, we tested different interfacial layer materials like polyethylenimine (PEI and PEDOT:PSS, and silver as a non-transparent electrode material. We also built organic light emitting diodes applying the same device designs demonstrating the versatility of applied layer stacks. The proposed design should allow the preparation of organic bulk-heterojunction modules with minimized photovoltaically inactive regions at the interconnection of individual devices.

  20. MOBILE DEVICES AND EFFECTIVE INFORMATION SECURITY

    Directory of Open Access Journals (Sweden)

    Igor Bernik

    2013-05-01

    Full Text Available Rapidly increasing numbers of sophisticated mobile devices (smart phones, tab computers, etc. all over the world mean that ensuring information security will only become a more pronounced problem for individuals and organizations. It’s important to effectively protect data stored on or accessed by mobile devices, and also during transmission of data between devices and between device and information system. Technological and other trends show, that the cyber threats are also rapidly developing and spreading. It's crucial to educate users about safe usage and to increase their awareness of security issues. Ideally, users should keep-up with technological trends and be well equipped with knowledge otherwise mobile technology will significantly increase security risks. Most important is that we start educating youth so that our next generations of employees will be part of a culture of data and information security awareness.

  1. Railgun-type two step accelerator

    International Nuclear Information System (INIS)

    Kasai, Satoshi; Maeda, Hikosuke; Onozuka, Masanori; Oda, Yasutsugu; Azuma, Kingo.

    1995-01-01

    In the two step-type railgun accelerator used in an experimental nuclear fusion device of the present invention, energy of laser beams to be irradiated in an acceleration gas behind a flying object can be reduced, and the voltage applied between the rails can be lowered. Charged particles are generated and supplied to the acceleration gas behind the flying object by a charged particle generating and supplying device so as to promote generation of plasmas caused by irradiation of laser beams. As a result, dielectric break down is caused between the rails by a Paschen's law by application of voltage lower than dielectric breakdown voltage, thereby enabling to generate plasmas easily. Accordingly, the energy of laser beams can be suppressed and the voltage applied between the rails can be lowered. (I.S.)

  2. Railgun-type two step accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Kasai, Satoshi; Maeda, Hikosuke [Japan Atomic Energy Research Inst., Tokyo (Japan); Onozuka, Masanori; Oda, Yasutsugu; Azuma, Kingo

    1995-10-13

    In the two step-type railgun accelerator used in an experimental nuclear fusion device of the present invention, energy of laser beams to be irradiated in an acceleration gas behind a flying object can be reduced, and the voltage applied between the rails can be lowered. Charged particles are generated and supplied to the acceleration gas behind the flying object by a charged particle generating and supplying device so as to promote generation of plasmas caused by irradiation of laser beams. As a result, dielectric break down is caused between the rails by a Paschen`s law by application of voltage lower than dielectric breakdown voltage, thereby enabling to generate plasmas easily. Accordingly, the energy of laser beams can be suppressed and the voltage applied between the rails can be lowered. (I.S.).

  3. Crystal step edges can trap electrons on the surfaces of n-type organic semiconductors.

    Science.gov (United States)

    He, Tao; Wu, Yanfei; D'Avino, Gabriele; Schmidt, Elliot; Stolte, Matthias; Cornil, Jérôme; Beljonne, David; Ruden, P Paul; Würthner, Frank; Frisbie, C Daniel

    2018-05-30

    Understanding relationships between microstructure and electrical transport is an important goal for the materials science of organic semiconductors. Combining high-resolution surface potential mapping by scanning Kelvin probe microscopy (SKPM) with systematic field effect transport measurements, we show that step edges can trap electrons on the surfaces of single crystal organic semiconductors. n-type organic semiconductor crystals exhibiting positive step edge surface potentials display threshold voltages that increase and carrier mobilities that decrease with increasing step density, characteristic of trapping, whereas crystals that do not have positive step edge surface potentials do not have strongly step density dependent transport. A device model and microelectrostatics calculations suggest that trapping can be intrinsic to step edges for crystals of molecules with polar substituents. The results provide a unique example of a specific microstructure-charge trapping relationship and highlight the utility of surface potential imaging in combination with transport measurements as a productive strategy for uncovering microscopic structure-property relationships in organic semiconductors.

  4. Photochemical separation and extraction device

    International Nuclear Information System (INIS)

    Wada, Yukio; Morimoto, Kyoichi.

    1998-01-01

    The present invention concerns a device for separating neptunium and plutonium from highly radioactive liquid wastes, in which valance control by irradiation of UV rays and extraction operation by using an organic solvent can be conducted simultaneously in the same reaction vessel. Namely, a step of irradiating UV rays to the liquid in the reaction vessel to control the valence of predetermined materials and a step of separating the materials by conducting solvent-extraction while stirring with a solvent are conducted simultaneously or successively. Then, facilities for the separation method can be reduced and the operation steps can be simplified. (N.H.)

  5. Effects of sterilization on the mechanical properties of poly(methyl methacrylate) based personalized medical devices.

    Science.gov (United States)

    Münker, T J A G; van de Vijfeijken, S E C M; Mulder, C S; Vespasiano, V; Becking, A G; Kleverlaan, C J; Becking, A G; Dubois, L; Karssemakers, L H E; Milstein, D M J; van de Vijfeijken, S E C M; Depauw, P R A M; Hoefnagels, F W A; Vandertop, W P; Kleverlaan, C J; Münker, T J A G; Maal, T J J; Nout, E; Riool, M; Zaat, S A J

    2018-05-01

    Nowadays, personalized medical devices are frequently used for patients. Due to the manufacturing procedure sterilization is required. How different sterilization methods affect the mechanical behavior of these devices is largely unknown. Three poly(methyl methacrylate) (PMMA) based materials (Vertex Self-Curing, Palacos R+G, and NextDent C&B MFH) were sterilized with different sterilization methods: ethylene oxide, hydrogen peroxide gas plasma, autoclavation, and γ-irradiation. Mechanical properties were determined by testing the flexural strength, flexural modulus, fracture toughness, and impact strength. The flexural strength of all materials was significantly higher after γ-irradiation compared to the control and other sterilization methods, as tested in a wet environment. NextDent C&B MFH showed the highest flexural and impact strength, Palacos R+G showed the highest maximum stress intensity factor and total fracture work. Autoclave sterilization is not suitable for the sterilization of PMMA-based materials. Ethylene oxide, hydrogen peroxide gas plasma, and γ-irradiation appear to be suitable techniques to sterilize PMMA-based personalized medical devices. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

  6. Step-Climbing Power Wheelchairs: A Literature Review

    Science.gov (United States)

    Sundaram, S. Andrea; Wang, Hongwu; Ding, Dan

    2017-01-01

    Background: Power wheelchairs capable of overcoming environmental barriers, such as uneven terrain, curbs, or stairs, have been under development for more than a decade. Method: We conducted a systematic review of the scientific and engineering literature to identify these devices, and we provide brief descriptions of the mechanism and method of operation for each. We also present data comparing their capabilities in terms of step climbing and standard wheelchair functions. Results: We found that all the devices presented allow for traversal of obstacles that cannot be accomplished with traditional power wheelchairs, but the slow speeds and small wheel diameters of some designs make them only moderately effective in the basic area of efficient transport over level ground and the size and configuration of some others limit maneuverability in tight spaces. Conclusion: We propose that safety and performance test methods more comprehensive than the International Organization for Standards (ISO) testing protocols be developed for measuring the capabilities of advanced wheelchairs with step-climbing and other environment-negotiating features to allow comparison of their clinical effectiveness. PMID:29339886

  7. Extraction of Human Stepping Pattern Using Acceleration Sensors

    Directory of Open Access Journals (Sweden)

    Toyohira Takayuki

    2017-01-01

    Full Text Available Gait analysis plays an important role in characterizing individuals and each condition and gait analysis systems have been developed using various devices or instruments. However, most systems do not catch synchronous stepping actions between right foot and left foot. For obtaining a precise gait pattern, a synchronous walking sensing system is developed, in which a pair of acceleration and angular velocity sensors are attached to left and right shoes of a walking person and their data are transmitted to a PC through a wireless channel. Walking data from 19 persons of the age of 14 to 20 are acquired for walking analysis. Stepping time diagrams are extracted from the acquired data of right and left foot actions of stepping-off and-on the ground, and the time diagrams distinguish between an ordinary person and a person injured on left leg, and a stepping recovery process of the injured person is shown. Synchronous sensing of stepping action between right foot and left foot contributes to obtain precise stepping patterns.

  8. Gate Engineering in SOI LDMOS for Device Reliability

    Directory of Open Access Journals (Sweden)

    Aanand

    2016-01-01

    Full Text Available A linearly graded doping drift region with step gate structure, used for improvement of reduced surface field (RESURF SOI LDMOS transistor performance has been simulated with 0.35µm technology in this paper. The proposed device has one poly gate and double metal gate arranged in a stepped manner, from channel to drift region. The first gate uses n+ poly (near source where as other two gates of aluminium. The first gate with thin gate oxide has good control over the channel charge. The third gate with thick gate oxide at drift region reduce gate to drain capacitance. The arrangement of second and third gates in a stepped manner in drift region spreads the electric field uniformly. Using two dimensional device simulations, the proposed SOI LDMOS is compared with conventional structure and the extended metal structure. We demonstrate that the proposed device exhibits significant enhancement in linearity, breakdown voltage, on-resistance and HCI. Double metal gate reduces the impact ionization area which helps to improve the Hot Carrier Injection effect..

  9. Subtitle Synchronization across Multiple Screens and Devices

    Directory of Open Access Journals (Sweden)

    Aitor Rodriguez-Alsina

    2012-06-01

    Full Text Available Ambient Intelligence is a new paradigm in which environments are sensitive and responsive to the presence of people. This is having an increasing importance in multimedia applications, which frequently rely on sensors to provide useful information to the user. In this context, multimedia applications must adapt and personalize both content and interfaces in order to reach acceptable levels of context-specific quality of service for the user, and enable the content to be available anywhere and at any time. The next step is to make content available to everybody in order to overcome the existing access barriers to content for users with specific needs, or else to adapt to different platforms, hence making content fully usable and accessible. Appropriate access to video content, for instance, is not always possible due to the technical limitations of traditional video packaging, transmission and presentation. This restricts the flexibility of subtitles and audio-descriptions to be adapted to different devices, contexts and users. New Web standards built around HTML5 enable more featured applications with better adaptation and personalization facilities, and thus would seem more suitable for accessible AmI environments. This work presents a video subtitling system that enables the customization, adaptation and synchronization of subtitles across different devices and multiple screens. The benefits of HTML5 applications for building the solution are analyzed along with their current platform support. Moreover, examples of the use of the application in three different cases are presented. Finally, the user experience of the solution is evaluated.

  10. Energetics and Dynamics of Cu(001)-c(2x2)Cl steps

    NARCIS (Netherlands)

    van Dijk, F.R.; Zandvliet, Henricus J.W.; Poelsema, Bene

    2006-01-01

    The energetics of the step faceting transition of Cu(001) [copper (001) surface] upon Cl (chloride) adsorption in contact with HCl (hydrogen chloride) solution is modeled in terms of a solid-on-solid model that incorporates both nearest-neighbor and next-nearest-neighbor interactions. It is shown

  11. Intelligent hearing aids: the next revolution.

    Science.gov (United States)

    Tao Zhang; Mustiere, Fred; Micheyl, Christophe

    2016-08-01

    The first revolution in hearing aids came from nonlinear amplification, which allows better compensation for both soft and loud sounds. The second revolution stemmed from the introduction of digital signal processing, which allows better programmability and more sophisticated algorithms. The third revolution in hearing aids is wireless, which allows seamless connectivity between a pair of hearing aids and with more and more external devices. Each revolution has fundamentally transformed hearing aids and pushed the entire industry forward significantly. Machine learning has received significant attention in recent years and has been applied in many other industries, e.g., robotics, speech recognition, genetics, and crowdsourcing. We argue that the next revolution in hearing aids is machine intelligence. In fact, this revolution is already quietly happening. We will review the development in at least three major areas: applications of machine learning in speech enhancement; applications of machine learning in individualization and customization of signal processing algorithms; applications of machine learning in improving the efficiency and effectiveness of clinical tests. With the advent of the internet of things, the above developments will accelerate. This revolution will bring patient satisfactions to a new level that has never been seen before.

  12. Improvement of a device for region radiation survey

    International Nuclear Information System (INIS)

    Poltinnikov, S.A.

    1978-01-01

    The electromechnanical device based on coding the turning angle of an automobile wheel by the number of electric pulses controlling the step motor of a film gate of gamma radiometer is proposed. The device is intended for automatizing recordings of gamma-radiation levels depending on a certain distance in a given terrain. The device has been tested at car speeds from 10 to 80 km/hr

  13. Feasibility and application on steam injector for next-generation reactor

    International Nuclear Information System (INIS)

    Narabayashi, Tadashi; Ishiyama, Takenori; Miyano, Hiroshi; Nei, Hiromichi; Shioiri, Akio

    1991-01-01

    A feasibility study has been conducted on steam injector for a next generation reactor. The steam injector is a simple, compact passive device for water injection, such as Passive Core Injection System (PCIS) of Passive Containment Cooling System (PCCS), because of easy start-up without an AC power. An analysis model for a steam injector characteristics has been developed, and investigated with a visualized fundamental test for a two-stage Steam Injector System (SIS) for PCIS and a one-stage low pressure SIS for PCCS. The test results showed good agreement with the analysis results. The analysis and the test results showed the SIS could work over a very wide range of the steam pressure, and is applicable for PCIS or PCCS in the next generation reactors. (author)

  14. Mars via the Moon the next giant leap

    CERN Document Server

    Seedhouse, Erik

    2016-01-01

    MOMENTUM IS BUILDING for a return to the Moon. NASA’s international partners on the International Space Station are in favor of returning to the lunar surface, as are India and China. The horizon goal may be Mars, but the political, funding and the technological and medical infeasibility of such an objective means the next logical step is a return to the Moon. While much has been learned about the Moon over the years, we don’t understand its resource wealth potential and the technologies to exploit those resources have yet to be developed, but there are a number of companies that are developing these capabilities. And, with the discovery of water in the lunar polar regions, plans are in the works to exploit these resources for fuel for transportation operations in cis-lunar space and in low Earth orbit (LEO). The time has come for commercial enterprise to lead the way back to the lunar surface. Embarking on such a venture requires little in the way of new technologies. We don’t need to develop super-fas...

  15. Fibre optic communication key devices

    CERN Document Server

    Grote, Norbert

    2017-01-01

    The book gives an in-depth description of key devices of current and next generation fibre optic communication networks. Devices treated include semiconductor lasers, optical amplifiers, modulators, wavelength filters and other passives, detectors, all-optical switches, but relevant properties of optical fibres and network aspects are included as well. The presentations include the physical principles underlying the various devices, technologies used for their realization, typical performance characteristics and limitations, but development trends towards more advanced components are also illustrated. This new edition of a successful book was expanded and updated extensively. The new edition covers among others lasers for optical communication, optical switches, hybrid integration, monolithic integration and silicon photonics. The main focus is on Indium phosphide-based structures but silicon photonics is included as well. The book covers relevant principles, state-of-the-art implementations, status of curren...

  16. 3G, 4G and beyond bringing networks, devices and the web together

    CERN Document Server

    Sauter, Martin

    2012-01-01

    Extensively updated evaluation of current and future network technologies, applications and devices  This book follows on from its successful predecessor with an introduction to next generation network technologies, mobile devices, voice and multimedia services and the mobile web 2.0.  Giving a sound technical introduction to 3GPP wireless systems, this book explains the decisions taken during standardization of the most popular wireless network standards today, LTE, LTE-Advanced and HSPA+.  It discusses how these elements strongly influence each other and how network ca

  17. MoonNEXT: A European Mission to the Moon

    Science.gov (United States)

    Carpenter, J. D.; Koschny, D.; Crawford, I.; Falcke, H.; Kempf, S.; Lognonne, P.; Ricci, C.; Houdou, B.; Pradier, A.

    2008-09-01

    rover, if shown to be feasible, would provide mobility for geochemical measurements, which is essential if geological units are to be examined in context. In the region around the South pole of the Moon investigations into excavated material related to the Aitken basin will require mobility to access the blocky ejecta fields associated with ~100m diameter craters. Mobility could also provide a means for the deployment of a network of short period seismometers for studies of regolith properties and the meteorite flux. The separation of the rover from the lander would provide a baseline for radio interferometry, which could provide the first ever image of the sky at wavelengths inaccessible from the Earth. MoonNEXT and the International Lunar Network In early 2008 NASA presented the concept of the International Lunar Network (ILN) this would comprise a network of several landers, provided by various countries and international agencies, which would be distributed at various locations across the surface of the Moon. Each of these landers would include a package for making geophysical measurements and their combined data set would provide detail on the internal structure and history of the Moon which is only possible through a globally distributed network. The proposed landing site, scientific instrument package and mission timescale for MoonNEXT mean that it is well suited as a European node to the ILN. Summary and Conclusions MoonNEXT is an ESA mission to the Lunar South Pole. MoonNEXT prepares the way for future exploration activities through technology demonstratin and characterisation of the landing site and its environment. In addition MoonNEXT addresses fundamental science questions relating to geophysics, geochemistry and the lunar environment. As a stand alone mission MoonNEXT provides a valuable step in the exploration and understanding of the Moon. This mission is also potentially an important European contribution to the International Lunar Network.

  18. Transfection in perfused microfluidic cell culture devices: A case study.

    Science.gov (United States)

    Raimes, William; Rubi, Mathieu; Super, Alexandre; Marques, Marco P C; Veraitch, Farlan; Szita, Nicolas

    2017-08-01

    Automated microfluidic devices are a promising route towards a point-of-care autologous cell therapy. The initial steps of induced pluripotent stem cell (iPSC) derivation involve transfection and long term cell culture. Integration of these steps would help reduce the cost and footprint of micro-scale devices with applications in cell reprogramming or gene correction. Current examples of transfection integration focus on maximising efficiency rather than viable long-term culture. Here we look for whole process compatibility by integrating automated transfection with a perfused microfluidic device designed for homogeneous culture conditions. The injection process was characterised using fluorescein to establish a LabVIEW-based routine for user-defined automation. Proof-of-concept is demonstrated by chemically transfecting a GFP plasmid into mouse embryonic stem cells (mESCs). Cells transfected in the device showed an improvement in efficiency (34%, n = 3) compared with standard protocols (17.2%, n = 3). This represents a first step towards microfluidic processing systems for cell reprogramming or gene therapy.

  19. A MODFLOW Infiltration Device Package for Simulating Storm Water Infiltration.

    Science.gov (United States)

    Jeppesen, Jan; Christensen, Steen

    2015-01-01

    This article describes a MODFLOW Infiltration Device (INFD) Package that can simulate infiltration devices and their two-way interaction with groundwater. The INFD Package relies on a water balance including inflow of storm water, leakage-like seepage through the device faces, overflow, and change in storage. The water balance for the device can be simulated in multiple INFD time steps within a single MODFLOW time step, and infiltration from the device can be routed through the unsaturated zone to the groundwater table. A benchmark test shows that the INFD Package's analytical solution for stage computes exact results for transient behavior. To achieve similar accuracy by the numerical solution of the MODFLOW Surface-Water Routing (SWR1) Process requires many small time steps. Furthermore, the INFD Package includes an improved representation of flow through the INFD sides that results in lower infiltration rates than simulated by SWR1. The INFD Package is also demonstrated in a transient simulation of a hypothetical catchment where two devices interact differently with groundwater. This simulation demonstrates that device and groundwater interaction depends on the thickness of the unsaturated zone because a shallow groundwater table (a likely result from storm water infiltration itself) may occupy retention volume, whereas a thick unsaturated zone may cause a phase shift and a change of amplitude in groundwater table response to a change of infiltration. We thus find that the INFD Package accommodates the simulation of infiltration devices and groundwater in an integrated manner on small as well as large spatial and temporal scales. © 2014, National Ground Water Association.

  20. Firewood preparation devices in 1994

    International Nuclear Information System (INIS)

    Mutikainen, A.

    1994-01-01

    A review of the market situation regarding firewood preparation devices is presented. The information was collected from the answers to a mail questionnaire. The review is assumed to include all the leading manufacturers and importers. Firewood production devices were available from 26 manufacturers. The range of models amounted to over 70. These may be divided into three categories: 1. cutting devices: the most common solution being a cross-cutting circular saw. There were only a few of these on sale as it is quite easy to include a splitting device on the same frame. 2. Splitting devices: e.g. screw splitter and hydraulically powered splitter. About 20 models are available on the markets. Cross cutting and splitting devices: these are the most popular devices. A cross-cutting circular saw with screw or hydraulic splitter is the most common type. There are about 50 models available on the markets. Cross-cutting and splitting devices are often equipped with conveyor for transferring the split wood e.g. into a trailer. Chopping devices are delivered as tractor powered devices, as electric motor powered devices or as combustion engine powered devices. Some of them are equipped with a time saving feeding device enabling the next stem to be lifted into position while the previous one is being chopped. The Finnish Work Efficiency Institute's studies show that when cross-cutting and splitting of stems into pieces of 35-50 cm in length, productivity for one operator varies in between 0.8 - 3.2 m 3 /h, depending on the device and work method used. (6 refs., 1 fig., 2 tabs.)

  1. Extended device profiles and testing procedures for the approval process of integrated medical devices using the IEEE 11073 communication standard.

    Science.gov (United States)

    Janß, Armin; Thorn, Johannes; Schmitz, Malte; Mildner, Alexander; Dell'Anna-Pudlik, Jasmin; Leucker, Martin; Radermacher, Klaus

    2018-02-23

    Nowadays, only closed and proprietary integrated operating room systems (IORS) from big manufacturers are available on the market. Hence, the interconnection of components from third-party vendors is only possible with increased time and costs. In the context of the German Federal Ministry of Education and Research (BMBF)-funded project OR.NET (2012-2016), the open integration of medical devices from different manufacturers was addressed. An integrated operating theater based on the open communication standard IEEE 11073 shall give clinical operators the opportunity to choose medical devices independently of the manufacturer. This approach would be advantageous especially for hospital operators and small- and medium-sized enterprises (SME) of medical devices. Actual standards and concepts regarding technical feasibility and the approval process do not cope with the requirements for a modular integration of medical devices in the operating room (OR), based on an open communication standard. Therefore, innovative approval strategies and corresponding certification and test procedures, which cover actual legal and normative standards, have to be developed in order to support the future risk management and the usability engineering process of open integrated medical devices in the OR. The use of standardized device and service profiles and a three-step testing procedure, including conformity, interoperability and integration tests are described in this paper and shall support the manufacturers to integrate their medical devices without disclosing the medical devices' risk analysis and related confidential expertise or proprietary information.

  2. Rhamnolipids--next generation surfactants?

    Science.gov (United States)

    Müller, Markus Michael; Kügler, Johannes H; Henkel, Marius; Gerlitzki, Melanie; Hörmann, Barbara; Pöhnlein, Martin; Syldatk, Christoph; Hausmann, Rudolf

    2012-12-31

    combine a holistic X-omics strategy with metabolic engineering to achieve the next step in rhamnolipid production based on non-food renewable resources. This review discusses different approaches towards optimization of rhamnolipid production and enhancement of product spectra. The optimization of rhamnolipid production with P. aeruginosa strains, screening methods for new non-pathogenic natural rhamnolipid producers and recombinant rhamnolipid production are examined. Finally, biocatalysis with rhamnolipids for the synthesis of l-rhamnose, β-hydroxyfatty acids, and tailor-made surfactants is discussed. Biosurfactants are still in the phase of initial commercialization. However, for next generation development of rhamnolipid production processes and next generation biosurfactants there are still considerable obstacles to be surmounted, which are discussed here. Copyright © 2012 Elsevier B.V. All rights reserved.

  3. WEARABLE ELECTRONICS IN THE NEXT YEARS

    Directory of Open Access Journals (Sweden)

    PRINIOTAKIS George

    2015-05-01

    Full Text Available The term ‘Wearable Technologies’, ‘Wearable Electronics’, or ‘Smart Garments’, is associated to those clothing and soft or hard accessories which integrate electronic components, or which are made of smart textiles. Smart textiles research represents a new model for generating creative and novel solutions for integrating electronics into unusual environments and will result in new discoveries that push the boundaries of science forward. Last few years there are several hundreds or maybe thousands of research teams that works and develop such materials and products. But the key driver of the success of the wearable electronics is the acceptance from the end user. It is estimates that only for the next three years the sales in the wearable will be almost multiply by ten times. The flexible wearable computer industry's patent applications arrived at 429 in the second quarter of 2014, up 27.7% year on year, and witnessed a record high in the report's tracking period starting from the first quarter of 2012. The market has already in the shelf commercial products as wristbands (Fitness/well-being/sports devices, smart jewels, smart watches, mobile health devices, tech clothing, and augmented reality glasses. The recently developed enabling technologies eliminates the barriers and help the scientists and developers to launch new types of "wearable". The life style of a large share of population, the low cost of 3D printing for rapid prototyping locally, the large available platforms, the lower cost of sensors and components give a an impetus for large scale of products. In the same time the direct ordering channels to manufacturers of components facilitates the small producers and the scientists for prototype development. In this article we identify key challenges for the success of the wearable and we provide an outlook over the field and a prediction for the near future.

  4. Validation of DRAGON side-step method for Bruce-A restart Phase-B physics tests

    International Nuclear Information System (INIS)

    Shen, W.; Ngo-Trong, C.; Davis, R.S.

    2004-01-01

    The DRAGON side-step method, developed at AECL, has a number of advantages over the all-DRAGON method that was used before. It is now the qualified method for reactivity-device calculations. Although the side-step-method-generated incremental cross sections have been validated against those previously calculated with the all-DRAGON method, it is highly desirable to validate the side-step method against device-worth measurements in power reactors directly. In this paper, the DRAGON side-step method was validated by comparison with the device-calibration measurements made in Bruce-A NGS Unit 4 restart Phase-B commissioning in 2003. The validation exercise showed excellent results, with the DRAGON code overestimating the measured ZCR worth by ∼5%. A sensitivity study was also performed in this paper to assess the effect of various DRAGON modelling techniques on the incremental cross sections. The assessment shows that the refinement of meshes in 3-D and the use of the side-step method are two major reasons contributing to the improved agreement between the calculated ZCR worths and the measurements. Use of different DRAGON versions, DRAGON libraries, local-parameter core conditions, and weighting techniques for the homogenization of tube clusters inside the ZCR have a very small effect on the ZCR incremental thermal absorption cross section and ZCR reactivity worth. (author)

  5. Status of the apeNEXT project

    CERN Document Server

    Ammendola, R.; Boucaud, Philippe; Cabibbo, N.; Di Carlo, F.; De Pietri, R.; Di Renzo, F.; Errico, W.; Fucci, A.; Guagnelli, M.; Kaldass, H.; Lonardo, A.; de Luca, S.; Micheli, J.; Morenas, V.; Pene, O.; Petronzio, R.; Palombi, F.; Pleiter, D.; Paschedag, N.; Rapuano, F.; De Riso, P.; Rossetti, D.; Salamon, A.; Salina, G.; Sartori, L.; Schifano, F.; Simma, H.; Tripiccione, R.; Vicini, P.; Boucaud, Ph.; 10.1016/S0920-5632(03)01755-9

    2003-01-01

    We present the current status of the apeNEXT project. Aim of this project is the development of the next generation of APE machines which will provide multi-teraflop computing power. Like previous machines, apeNEXT is based on a custom designed processor, which is specifically optimized for simulating QCD. We discuss the machine design, report on benchmarks, and give an overview on the status of the software development.

  6. Medical device development.

    Science.gov (United States)

    Panescu, Dorin

    2009-01-01

    The development of a successful medical product requires not only engineering design efforts, but also clinical, regulatory, marketing and business expertise. This paper reviews items related to the process of designing medical devices. It discusses the steps required to take a medical product idea from concept, through development, verification and validation, regulatory approvals and market release.

  7. Multidimensional materials and device architectures for future hybrid energy storage

    Science.gov (United States)

    Lukatskaya, Maria R.; Dunn, Bruce; Gogotsi, Yury

    2016-09-01

    Electrical energy storage plays a vital role in daily life due to our dependence on numerous portable electronic devices. Moreover, with the continued miniaturization of electronics, integration of wireless devices into our homes and clothes and the widely anticipated `Internet of Things', there are intensive efforts to develop miniature yet powerful electrical energy storage devices. This review addresses the cutting edge of electrical energy storage technology, outlining approaches to overcome current limitations and providing future research directions towards the next generation of electrical energy storage devices whose characteristics represent a true hybridization of batteries and electrochemical capacitors.

  8. Next step in change: The ''learning organization''

    International Nuclear Information System (INIS)

    Ross, C.E.H.

    1996-01-01

    Although the cost reductions over the past 15 years were painful, they forced the petroleum industry to put resources to work more efficiently, and now they're doing many of the right things in the right ways. Foremost, they've been finding and developing new oil resources from a wide variety of sources at low costs, even while in many areas the quality of the resource base has continued to deteriorate. They've also made great progress in stripping costs out of the entire supply chain, remediating environmental problems, reformulating fuels, and managing risk. In a low price environment, performance improvement is the name of the game, and over time a number of tools have been created to help meet this challenge. Because these tools have been developed successively, each building upon the accomplishments of its predecessors, the author sees them as the ''building blocks'' of organizational transformation. The latest building block -- and one that a lot of thought is being put into at Arthur D. Little -- is the ''learning organization.'' This and the other building blocks are discussed (decentralization, total quality management, business process redesign, high performance business, and virtualization)

  9. Multidisciplinary Teams: The Next Step in Science.

    Directory of Open Access Journals (Sweden)

    Aldo Leal-Egaña.

    2006-07-01

    Full Text Available One of the current characteristics in science, is the high complexity and technical character that becomes over the last years. This has induced the development of a specific type of professionals, highly specialized in the disciplines that they are involved in, which has produced a communicational breach between the scientists involved on different branches of the science. One of the strategies intended to cross this breach, is the generation of multidisciplinary research strategies, in which professionals of every field of the science can take part, being a kind of scientific and human bridge between the different research teams where they are involved in. This new style to do investigation has made possible the generation of new branches in science, such as for example Biotechnology. In this field -Tissue Engineering- becomes to be a very interesting example of the potential to work in multidisciplinary teams. The reason for this is mainly to avoid technical mistakes, which could cause the death of some patients and which can only be solved by developing research under a multidisciplinary strategy. Nevertheless, and in spite of the success working with multidisciplinary teams, this kind of strategy is rarely used in Latin-American, where the reasons seems to be centered in some aspects personal and cultural. This work shows an example of the new style to develop complex research, which could suggest a new way of working in Latin-American, granted that there is the will to enhance current scientific level.

  10. Student Use of Mobile Devices in Course Evaluation: A Longitudinal Study

    Science.gov (United States)

    Champagne, Matthew V.

    2013-01-01

    A 2012 survey of higher education found that 27% of colleges and universities were "mobile ready", that is, allowing students to complete course evaluations via mobile devices, and 26% of schools planned to allow the use of mobile devices for course evaluations within the next year. The purpose of this study was to prepare for this…

  11. Virtualization, The next step for online services

    Directory of Open Access Journals (Sweden)

    Haller Piroska

    2013-06-01

    Full Text Available Virtualization allows sharing and allocating the hardware resources to more virtual machines thus increasing their usage rate. There are multiple solutions available today such as VMware vSphere, Microsoft Hyper-V, Xen Server and Red Hat KVM each with its own advantages and disadvantages. Choosing the right virtualization solution largely depends on the used applications and their resources requirements. The comparative analysis of the available virtualization solutions shows that it is essential to establish performance criteria’s and minimum and maximum resources usage thresholds over a given period of time. The coexistence of different services in different virtual machines that use different amount of resources allows a more efficient use of the available hardware resources.

  12. Enhancing regional collaboration -- taking the next step

    OpenAIRE

    Temple, Jennie M.

    2007-01-01

    CHDS State/Local Enhancing regional collaboration has been identified as one of the eight National Priorities for Homeland Security by the president of the United States. While South Carolina has made significant efforts in expanding regional collaboration, such as the creation of regional Counter Terrorism Coordinating Councils (CTCCs), there is still much work to be done. There are several teams and capabilities in place throughout the state, but they are uncoordinated, lack structure,...

  13. Shield design for next-generation, low-neutron-fluence, superconducting tokamaks

    International Nuclear Information System (INIS)

    Lee, V.D.; Gohar, Y.

    1985-01-01

    A shield design using stainless steel (SST), water, boron carbide, lead, and concrete materials was developed for the next-generation tokamak device with superconducting toroidal field (TF) coils and low neutron fluence. A device such as the Tokamak Fusion Core Experiment (TFCX) is representative of the tokamak design which could use this shield design. The unique feature of this reference design is that a majority of the bulk steel in the shield is in the form of spherical balls with two small, flat spots. The balls are purchased from ball-bearing manufacturers and are added as bulk shielding to the void areas of builtup, structural steel shells which form the torus cavity of the plasma chamber. This paper describes the design configuration of the shielding components

  14. Shield design for next-generation, low-neutron-fluence, superconducting tokamaks

    International Nuclear Information System (INIS)

    Lee, V.D.; Gohar, Y.

    1985-01-01

    A shield design using stainless steel (SST), water, boron carbide, lead, and concrete materials was developed for the next-generation tokamak device with superconducting toroidal field (TF) coils and low neutron fluence. A device such as the Tokamak Fusion Core Experiment (TFCX) is representative of the tokamak design which could use this shield design. The unique feature of this reference design is that a majority of the bulk steel in the shield is in the form of spherical balls with two small, flat spots. The balls are purchased from ball-bearing manufacturers and are added as bulk shielding to the void areas of built-up, structural steel shells which form the torus cavity of the plasma chamber. This paper describes the design configuration of the shielding components

  15. Direct printed metal devices - The next level of computer-aided design and computer-aided manufacturing applications in the orthodontic care

    Directory of Open Access Journals (Sweden)

    Simon Graf

    2017-01-01

    Full Text Available As the whole world gets more digital, so do we. This article provides a basic know-how for the CAD/CAM-workflow for metallic orthodontic appliances. Demonstrating step-by-step how to design the appliance on a digital cast and laser-melting (3D metal printing it, till the final result, without any physical models.

  16. Electric deregulation in Texas : the next steps

    International Nuclear Information System (INIS)

    Giuliani, R.

    2004-01-01

    This presentation provided a look at the deregulated market in Texas and provided some statistics and facts about the Electric Reliability Council of Texas (ERCOT) which monitors the reliability of 37,000 miles of power transmission lines and 77,000 MW of generation. The governance adopted by ERCOT was described along with market design and wholesale operation in terms of open access to transmission and distribution systems, reliability, timely conveyance of information needed to support customer choice, and accurate accountability for electricity production and delivery. Transmission has been one the greatest challenges facing ERCOT, but retail operations are progressing well despite initial start-up problems. tabs., figs

  17. Synchronization of Harb-Zohdy Chaotic System via Back-Stepping Design

    Directory of Open Access Journals (Sweden)

    M. R. Shamsyeh Zahedi∗

    2015-12-01

    Full Text Available This paper is concerned with the problem of synchronization of the Harb-Zohdy chaotic system using the back-stepping. Based on the stability theory, the control for the synchronization of chaotic systems Harb-Zohdy is considered without unknown parameters. Next, an adaptive back-stepping control law is derived to generate an error signal between the drive and response systems Harb-Zohdy with an uncertain parameter asymptotically synchronized. Finally, this method is extended to synchronize the system with two unknown parameters. Note that the method presented here needs only one controller to realize the synchronization. Numerical simulations indicate the effectiveness of the proposed chaos synchronization scheme

  18. Robotic retroperitoneal partial nephrectomy: a step-by-step guide.

    Science.gov (United States)

    Ghani, Khurshid R; Porter, James; Menon, Mani; Rogers, Craig

    2014-08-01

    To describe a step-by-step guide for successful implementation of the retroperitoneal approach to robotic partial nephrectomy (RPN) PATIENTS AND METHODS: The patient is placed in the flank position and the table fully flexed to increase the space between the 12th rib and iliac crest. Access to the retroperitoneal space is obtained using a balloon-dilating device. Ports include a 12-mm camera port, two 8-mm robotic ports and a 12-mm assistant port placed in the anterior axillary line cephalad to the anterior superior iliac spine, and 7-8 cm caudal to the ipsilateral robotic port. Positioning and port placement strategies for successful technique include: (i) Docking robot directly over the patient's head parallel to the spine; (ii) incision for camera port ≈1.9 cm (1 fingerbreadth) above the iliac crest, lateral to the triangle of Petit; (iii) Seldinger technique insertion of kidney-shaped balloon dilator into retroperitoneal space; (iv) Maximising distance between all ports; (v) Ensuring camera arm is placed in the outer part of the 'sweet spot'. The retroperitoneal approach to RPN permits direct access to the renal hilum, no need for bowel mobilisation and excellent visualisation of posteriorly located tumours. © 2014 The Authors. BJU International © 2014 BJU International.

  19. Doctor of Professional Counseling: The Next Step

    Science.gov (United States)

    Southern, Stephen; Cade, Rochelle; Locke, Don W.

    2012-01-01

    Professional doctorates have been established in the allied health professions by clinicians seeking the highest levels of independent practice. Allied health professional doctorates include nursing practice (DNP), occupational therapy (OTD), psychology (PsyD), social work (DSW), and marriage and family therapy (DMFT). Lessons learned from the…

  20. Asking how as a next step in avoiding dualistic perspectives on occupation

    DEFF Research Database (Denmark)

    Madsen, Jacob Østergaard; Josephsson, Staffan

    2017-01-01

    In their article “Filling in the gaps: A case for enhancing Madsen and Josephsson’s assertions about occupation, situation, and inquiry”, Aldrich and Cutchin (2017) responded to our article “Engagement in occupation as an inquiring process: Exploring the situatedness of occupation” with the ambit......In their article “Filling in the gaps: A case for enhancing Madsen and Josephsson’s assertions about occupation, situation, and inquiry”, Aldrich and Cutchin (2017) responded to our article “Engagement in occupation as an inquiring process: Exploring the situatedness of occupation......” with the ambition to enhance our assertions on occupation. In this reply, we argue that their text does not address the main arguments of our article. We further argue that their response confirms that further steps in exploring the situatedness of occupation by asking how situation and occupation are related...

  1. Multi-microelectrode devices for intrafascicular use in peripheral nerve

    NARCIS (Netherlands)

    Rutten, Wim

    1996-01-01

    This minisymposium paper gives an overview of experimental, modeling, design and microfabrication steps which lead towards the University of Twente three-dimensional 128-fold silicon microelectrode device. The device is meant for implantation in peripheral nerve for neuromuscular control purposes

  2. StarTrax --- The Next Generation User Interface

    Science.gov (United States)

    Richmond, Alan; White, Nick

    StarTrax is a software package to be distributed to end users for installation on their local computing infrastructure. It will provide access to many services of the HEASARC, i.e. bulletins, catalogs, proposal and analysis tools, initially for the ROSAT MIPS (Mission Information and Planning System), later for the Next Generation Browse. A user activating the GUI will reach all HEASARC capabilities through a uniform view of the system, independent of the local computing environment and of the networking method of accessing StarTrax. Use it if you prefer the point-and-click metaphor of modern GUI technology, to the classical command-line interfaces (CLI). Notable strengths include: easy to use; excellent portability; very robust server support; feedback button on every dialog; painstakingly crafted User Guide. It is designed to support a large number of input devices including terminals, workstations and personal computers. XVT's Portability Toolkit is used to build the GUI in C/C++ to run on: OSF/Motif (UNIX or VMS), OPEN LOOK (UNIX), or Macintosh, or MS-Windows (DOS), or character systems.

  3. The Next White (NEW) Detector

    Energy Technology Data Exchange (ETDEWEB)

    Monrabal, F.; et al.

    2018-04-06

    Conceived to host 5 kg of xenon at a pressure of 15 bar in the fiducial volume, the NEXT- White (NEW) apparatus is currently the largest high pressure xenon gas TPC using electroluminescent amplification in the world. It is also a 1:2 scale model of the NEXT-100 detector scheduled to start searching for $\\beta\\beta 0\

  4. 77 FR 69927 - Safety Advisory Notice: Safety Advisory for Shippers and Carriers of Air Bags

    Science.gov (United States)

    2012-11-21

    ... to devices containing unapproved explosives; and (4) provide the next steps that PHMSA will take to... parts. Some of these devices look nearly identical to legitimate products, including the branding of... pyrotechnic device, known as an initiator or electric match, consisting of an electrical conductor cocooned in...

  5. On the Properties and Design of Organic Light-Emitting Devices

    Science.gov (United States)

    Erickson, Nicholas C.

    Organic light-emitting devices (OLEDs) are attractive for use in next-generation display and lighting technologies. In display applications, OLEDs offer a wide emission color gamut, compatibility with flexible substrates, and high power efficiencies. In lighting applications, OLEDs offer attractive features such as broadband emission, high-performance, and potential compatibility with low-cost manufacturing methods. Despite recent demonstrations of near unity internal quantum efficiencies (photons out per electron in), OLED adoption lags conventional technologies, particularly in large-area displays and general lighting applications. This thesis seeks to understand the optical and electronic properties of OLED materials and device architectures which lead to not only high peak efficiency, but also reduced device complexity, high efficiency under high excitation, and optimal white-light emission. This is accomplished through the careful manipulation of organic thin film compositions fabricated via vacuum thermal evaporation, and the introduction of a novel device architecture, the graded-emissive layer (G-EML). This device architecture offers a unique platform to study the electronic properties of varying compositions of organic semiconductors and the resulting device performance. This thesis also introduces an experimental technique to measure the spatial overlap of electrons and holes within an OLED's emissive layer. This overlap is an important parameter which is affected by the choice of materials and device design, and greatly impacts the operation of the OLED at high excitation densities. Using the G-EML device architecture, OLEDs with improved efficiency characteristics are demonstrated, achieving simultaneously high brightness and high efficiency.

  6. The next step in a development of negative ion beam plasma neutraliser for ITER NBI

    International Nuclear Information System (INIS)

    Kulygin, V.M.; Dlougach, E.D.; Gorbunov, E.P.

    2001-01-01

    Injectors of deuterium atom beams developing for ITER plasma heating and current drive are based on the negative ion acceleration and further neutralization with a gas target. The maximal efficiency of a gas stripping process is 60%. The replacement of the gas neutralizer by plasma one must increase the neutral yield to 80%. The experimental study overview of the microwave discharge in a multi-cusp magnetic system chosen as a base device for Plasma Neutralizer realization and the design development for ITER Neutral Beam Injectors are presented. The experimental results achieved at a plasma neutralizer model PNX-U is discussed. Plasma confinement, gas flows, ionization degree were investigated. The plasma in the volume 0.5m 3 with density n e ∼ 10 18 m -3 has been achieved at power density 80kW/m 3 in operation with Argon. (author)

  7. On the development of automatic sample preparation devices

    International Nuclear Information System (INIS)

    Oesselmann, J.

    1987-01-01

    Modern mass spectrometers for stable isotope analysis offer accurate isotope ratio results from gaseous samples (CO 2 , N 2 , H 2 , SO 2 ) in a completely automated fashion. However, most samples of interest either are associated with contaminant gases or the gas has to be liberated by a chemical procedure prior to measurement. In most laboratories this sample preparation step is performed manually. As a consequence, sample throughput is rather low and - despite skilful operation - the preparation procedure varies slightly from one sample to the next affecting mainly the reproducibility of the data. (author)

  8. A novel thermal acoustic device based on porous graphene

    Science.gov (United States)

    Tao, Lu-Qi; Liu, Ying; Tian, He; Ju, Zhen-Yi; Xie, Qian-Yi; Yang, Yi; Ren, Tian-Ling

    2016-01-01

    A thermal acoustic (TA) device was fabricated by laser scribing technology. Polyimide (PI) can be converted into patterned porous graphene (PG) by laser's irradiation in one step. The sound pressure level (SPL) of such TA device is related to laser power. The theoretical model of TA effect was established to analyze the relationship between the SPL and laser power. The theoretical results are in good agreement with experiment results. It was found that PG has a flat frequency response in the range of 5-20 kHz. This novel TA device has the advantages of one-step procedure, high flexibility, no mechanical vibration, low cost and so on. It can open wide applications in speakers, multimedia, medical, earphones, consumer electronics and many other aspects.

  9. A novel thermal acoustic device based on porous graphene

    International Nuclear Information System (INIS)

    Tao, Lu-Qi; Liu, Ying; Ju, Zhen-Yi; Xie, Qian-Yi; Yang, Yi; Ren, Tian-Ling; Tian, He

    2016-01-01

    A thermal acoustic (TA) device was fabricated by laser scribing technology. Polyimide (PI) can be converted into patterned porous graphene (PG) by laser’s irradiation in one step. The sound pressure level (SPL) of such TA device is related to laser power. The theoretical model of TA effect was established to analyze the relationship between the SPL and laser power. The theoretical results are in good agreement with experiment results. It was found that PG has a flat frequency response in the range of 5-20 kHz. This novel TA device has the advantages of one-step procedure, high flexibility, no mechanical vibration, low cost and so on. It can open wide applications in speakers, multimedia, medical, earphones, consumer electronics and many other aspects

  10. A novel thermal acoustic device based on porous graphene

    Energy Technology Data Exchange (ETDEWEB)

    Tao, Lu-Qi; Liu, Ying; Ju, Zhen-Yi; Xie, Qian-Yi; Yang, Yi; Ren, Tian-Ling, E-mail: RenTL@tsinghua.edu.cn [Institute of Microelectronics, Tsinghua University, Beijing 10084 (China); Tsinghua National Laboratory for Information Science and Technology (TNList), Tsinghua University, Beijing 100084 (China); Tian, He [Ming Hsieh Department of Electrical Engineering, University of Southern California, Los Angeles, CA 90089 (United States)

    2016-01-15

    A thermal acoustic (TA) device was fabricated by laser scribing technology. Polyimide (PI) can be converted into patterned porous graphene (PG) by laser’s irradiation in one step. The sound pressure level (SPL) of such TA device is related to laser power. The theoretical model of TA effect was established to analyze the relationship between the SPL and laser power. The theoretical results are in good agreement with experiment results. It was found that PG has a flat frequency response in the range of 5-20 kHz. This novel TA device has the advantages of one-step procedure, high flexibility, no mechanical vibration, low cost and so on. It can open wide applications in speakers, multimedia, medical, earphones, consumer electronics and many other aspects.

  11. A step towards controlled fusion reactors: Tore Supra tokamak with superconducting magnets

    International Nuclear Information System (INIS)

    Turck, B.

    1988-01-01

    Tore Supra technology has to solve all the problems related to the development and the installaion of superconducting coils and associated cryogenic devices. Tore Supra will allow to get a significative experience to prepare next machines. Specifications and needs of tokamaks concerning the superconducting coils of future machines are recalled [fr

  12. Elucidating the diet of the island flying fox (Pteropus hypomelanus) in Peninsular Malaysia through Illumina Next-Generation Sequencing

    OpenAIRE

    Aziz, Sheema Abdul; Clements, Gopalasamy Reuben; Peng, Lee Yin; Campos-Arceiz, Ahimsa; McConkey, Kim R.; Forget, Pierre-Michel; Gan, Han Ming

    2017-01-01

    There is an urgent need to identify and understand the ecosystem services of pollination and seed dispersal provided by threatened mammals such as flying foxes. The first step towards this is to obtain comprehensive data on their diet. However, the volant and nocturnal nature of bats presents a particularly challenging situation, and conventional microhistological approaches to studying their diet can be laborious and time-consuming, and provide incomplete information. We used Illumina Next-G...

  13. Outlook: The Next Twenty Years

    Energy Technology Data Exchange (ETDEWEB)

    Murayama, Hitoshi

    2003-12-07

    I present an outlook for the next twenty years in particle physics. I start with the big questions in our field, broken down into four categories: horizontal, vertical, heaven, and hell. Then I discuss how we attack the bigquestions in each category during the next twenty years. I argue for a synergy between many different approaches taken in our field.

  14. Planning Instruction to Meet the Intent of the Next Generation Science Standards

    Science.gov (United States)

    Krajcik, Joseph; Codere, Susan; Dahsah, Chanyah; Bayer, Renee; Mun, Kongju

    2014-03-01

    The National Research Council's Framework for K- 12 Science Education and the Next Generation Science Standards (NGSS Lead States in Next Generation Science Standards: For states, by states. The National Academies Press, Washington, 2013) move teaching away from covering many isolated facts to a focus on a smaller number of disciplinary core ideas (DCIs) and crosscutting concepts that can be used to explain phenomena and solve problems by engaging in science and engineering practices. The NGSS present standards as knowledge-in-use by expressing them as performance expectations (PEs) that integrate all three dimensions from the Framework for K- 12 Science Education. This integration of core ideas, practices, and crosscutting concepts is referred to as three-dimensional learning (NRC in Division of Behavioral and Social Sciences and Education. The National Academies Press, Washington, 2014). PEs state what students can be assessed on at the end of grade level for K-5 and at the end of grade band for 6-8 and 9-12. PEs do not specify how instruction should be developed nor do they serve as objectives for individual lessons. To support students in developing proficiency in the PEs, the elements of the DCIs will need to be blended with various practices and crosscutting concepts. In this paper, we examine how to design instruction to support students in meeting a cluster or "bundle" of PEs and how to blend the three dimensions to develop lesson level PEs that can be used for guiding instruction. We provide a ten-step process and an example of that process that teachers and curriculum designers can use to design lessons that meet the intent of the Next Generation of Science Standards.

  15. Nuclear Knowledge to the Next Generation

    International Nuclear Information System (INIS)

    Mazour, Thomas; Kossilov, Andrei

    2004-01-01

    The safe, reliable, and cost-effective operation of Nuclear Power Plants (NPPs) requires that personnel possess and maintain the requisite knowledge, skills, and attitudes to do their jobs properly. Such knowledge includes not only the technical competencies required by the nature of the technology and particular engineering designs, but also the softer competencies associated with effective management, communication and teamwork. Recent studies have shown that there has been a loss of corporate knowledge and memory. Both explicit knowledge and tacit knowledge must be passed on to the next generation of workers in the industry to ensure a quality workforce. New and different techniques may be required to ensure timely and effective knowledge retention and transfer. The IAEA prepared a report on this subject. The main conclusions from the report regarding strategies for managing the aging workforce are included. Also included are main conclusions from the report regarding the capture an d preservation of mission critical knowledge, and the effective transfer of this knowledge to the next generation of NPP personnel. The nuclear industry due to its need for well-documented procedures, specifications, design basis, safety analyses, etc., has a greater fraction of its mission critical knowledge as explicit knowledge than do many other industries. This facilitates the task of knowledge transfer. For older plants in particular, there may be a need for additional efforts to transfer tacit knowledge to explicit knowledge to support major strategic initiatives such as plant license extensions/renewals, periodic safety reviews, major plant upgrades, and plant specific control room simulator development. The challenge in disseminating explicit knowledge is to make employees aware that it is available and provide easy access in formats and forms that are usable. Tacit knowledge is more difficult to identify and disseminate. The challenge is to identify what can be converted to

  16. Microfabricated Devices for Sample Extraction, Concentrations, and Related Sample Processing Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Gang; Lin, Yuehe

    2006-12-01

    This is an invited book chapter. As with other analytical techniques, sample pretreatments, sample extraction, sample introduction, and related techniques are of extreme importance for micro-electro-mechanical systems (MEMS). Bio-MEMS devices and systems start with a sampling step. The biological sample then usually undergoes some kinds of sample preparation steps before the actual analysis. These steps may involve extracting the target sample from its matrix, removing interferences from the sample, derivatizing the sample to detectable species, or performing a sample preconcentration step. The integration of the components for sample pretreatment into microfluidic devices represents one of the remaining the bottle-neck towards achieving true miniaturized total analysis systems (?TAS). This chapter provides a thorough state-of-art of the developments in this field to date.

  17. A SOM clustering pattern sequence-based next symbol prediction method for day-ahead direct electricity load and price forecasting

    International Nuclear Information System (INIS)

    Jin, Cheng Hao; Pok, Gouchol; Lee, Yongmi; Park, Hyun-Woo; Kim, Kwang Deuk; Yun, Unil; Ryu, Keun Ho

    2015-01-01

    Highlights: • A novel pattern sequence-based direct time series forecasting method was proposed. • Due to the use of SOM’s topology preserving property, only SOM can be applied. • SCPSNSP only deals with the cluster patterns not each specific time series value. • SCPSNSP performs better than recently developed forecasting algorithms. - Abstract: In this paper, we propose a new day-ahead direct time series forecasting method for competitive electricity markets based on clustering and next symbol prediction. In the clustering step, pattern sequence and their topology relations are obtained from self organizing map time series clustering. In the next symbol prediction step, with each cluster label in the pattern sequence represented as a pair of its topologically identical coordinates, artificial neural network is used to predict the topological coordinates of next day by training the relationship between previous daily pattern sequence and its next day pattern. According to the obtained topology relations, the nearest nonzero hits pattern is assigned to next day so that the whole time series values can be directly forecasted from the assigned cluster pattern. The proposed method was evaluated on Spanish, Australian and New York electricity markets and compared with PSF and some of the most recently published forecasting methods. Experimental results show that the proposed method outperforms the best forecasting methods at least 3.64%

  18. ICRF heating on helical devices

    International Nuclear Information System (INIS)

    Rasmussen, D.A.; Lyon, J.F.; Hoffman, D.J.; Murakami, M.; England, A.C.; Wilgen, J.B.; Jaeger, E.F.; Wang, C.; Batchelor, D.B.

    1995-01-01

    Ion cyclotron range of frequency (ICRF) heating is currently in use on CHS and W7-AS and is a major element of the heating planned for steady state helical devices. In helical devices, the lack of a toroidal current eliminates both disruptions and the need for ICRF current drive, simplifying the design of antenna structures as compared to tokamak applications. However the survivability of plasma facing components and steady state cooling issues are directly applicable to tokamak devices. Results from LHD steady state experiments should be available on a time scale to strongly influence the next generation of steady state tokamak experiments. The helical plasma geometry provides challenges not faced with tokamak ICRF heating, including the potential for enhanced fast ion losses, impurity accumulation, limited access for antenna structures, and open magnetic field lines in the plasma edge. The present results and near term plans provide the basis for steady state ICRF heating of larger helical devices. An approach which includes direct electron, mode conversion, ion minority and ion Bernstein wave heating addresses these issues

  19. ICRF heating on helical devices

    International Nuclear Information System (INIS)

    Rasmussen, D.A.; Lyon, J.F.; Hoffman, D.J.

    1995-01-01

    Ion cyclotron range of frequency (ICRF) heating is currently in use on CHS and W7AS and is a major element of the heating planned for steady state helical devices. In helical devices, the lack of a toroidal current eliminates both disruptions and the need for ICRF current drive, simplifying the design of antenna structures as compared to tokamak applications. However the survivability of plasma facing components and steady state cooling issues are directly applicable to tokamak devices. Results from LHD steady state experiments should be available on a time scale to strongly influence the next generation of steady state tokamak experiments. The helical plasma geometry provides challenges not faced with tokamak ICRF heating, including the potential for enhanced fast ion losses, impurity accumulation, limited access for antenna structures, and open magnetic field lines in the plasma edge. The present results and near term plans provide the basis for steady state ICRF heating of larger helical devices. An approach which includes direct electron, mode conversion, ion minority and ion Bernstein wave heating addresses these issues

  20. One-step sol-gel imprint lithography for guided-mode resonance structures.

    Science.gov (United States)

    Huang, Yin; Liu, Longju; Johnson, Michael; C Hillier, Andrew; Lu, Meng

    2016-03-04

    Guided-mode resonance (GMR) structures consisting of sub-wavelength periodic gratings are capable of producing narrow-linewidth optical resonances. This paper describes a sol-gel-based imprint lithography method for the fabrication of submicron 1D and 2D GMR structures. This method utilizes a patterned polydimethylsiloxane (PDMS) mold to fabricate the grating coupler and waveguide for a GMR device using a sol-gel thin film in a single step. An organic-inorganic hybrid sol-gel film was selected as the imprint material because of its relatively high refractive index. The optical responses of several sol-gel GMR devices were characterized, and the experimental results were in good agreement with the results of electromagnetic simulations. The influence of processing parameters was investigated in order to determine how finely the spectral response and resonant wavelength of the GMR devices could be tuned. As an example potential application, refractometric sensing experiments were performed using a 1D sol-gel device. The results demonstrated a refractive index sensitivity of 50 nm/refractive index unit. This one-step fabrication process offers a simple, rapid, and low-cost means of fabricating GMR structures. We anticipate that this method can be valuable in the development of various GMR-based devices as it can readily enable the fabrication of complex shapes and allow the doping of optically active materials into sol-gel thin film.

  1. One-step sol–gel imprint lithography for guided-mode resonance structures

    International Nuclear Information System (INIS)

    Huang, Yin; Liu, Longju; Lu, Meng; Johnson, Michael; C Hillier, Andrew

    2016-01-01

    Guided-mode resonance (GMR) structures consisting of sub-wavelength periodic gratings are capable of producing narrow-linewidth optical resonances. This paper describes a sol–gel-based imprint lithography method for the fabrication of submicron 1D and 2D GMR structures. This method utilizes a patterned polydimethylsiloxane (PDMS) mold to fabricate the grating coupler and waveguide for a GMR device using a sol–gel thin film in a single step. An organic–inorganic hybrid sol–gel film was selected as the imprint material because of its relatively high refractive index. The optical responses of several sol–gel GMR devices were characterized, and the experimental results were in good agreement with the results of electromagnetic simulations. The influence of processing parameters was investigated in order to determine how finely the spectral response and resonant wavelength of the GMR devices could be tuned. As an example potential application, refractometric sensing experiments were performed using a 1D sol–gel device. The results demonstrated a refractive index sensitivity of 50 nm/refractive index unit. This one-step fabrication process offers a simple, rapid, and low-cost means of fabricating GMR structures. We anticipate that this method can be valuable in the development of various GMR-based devices as it can readily enable the fabrication of complex shapes and allow the doping of optically active materials into sol–gel thin film. (paper)

  2. Initial results of NEXT-DEMO, a large-scale prototype of the NEXT-100 experiment

    International Nuclear Information System (INIS)

    Álvarez, V; Cárcel, S; Cervera, A; Díaz, J; Ferrario, P; Gil, A; Borges, F I G; Conde, C A N; Dias, T H V T; Fernandes, L M P; Freitas, E D C; Castel, J; Cebrián, S; Dafni, T; Egorov, M; Gehman, V M; Goldschmidt, A; Esteve, R; Evtoukhovitch, P; Ferreira, A L

    2013-01-01

    NEXT-DEMO is a large-scale prototype of the NEXT-100 detector, an electroluminescent time projection chamber that will search for the neutrinoless double beta decay of XE using 100–150 kg of enriched xenon gas. NEXT-DEMO was built to prove the expected performance of NEXT-100, namely, energy resolution better than 1% FWHM at 2.5 MeV and event topological reconstruction. In this paper we describe the prototype and its initial results. A resolution of 1.75% FWHM at 511 keV (which extrapolates to 0.8% FWHM at 2.5 MeV) was obtained at 10 bar pressure using a gamma-ray calibration source. Also, a basic study of the event topology along the longitudinal coordinate is presented, proving that it is possible to identify the distinct dE/dx of electron tracks in high-pressure xenon using an electroluminescence TPC.

  3. The way to collisions, step by step

    CERN Multimedia

    2009-01-01

    While the LHC sectors cool down and reach the cryogenic operating temperature, spirits are warming up as we all eagerly await the first collisions. No reason to hurry, though. Making particles collide involves the complex manoeuvring of thousands of delicate components. The experts will make it happen using a step-by-step approach.

  4. Limited Awareness of the Essences of Certification or Compliance Markings on Medical Devices.

    Science.gov (United States)

    Foo, Jong Yong Abdiel; Tan, Xin Ji Alan

    2017-06-01

    Medical devices have been long used for odiagnostic, therapeutic or rehabilitation purposes. Currently, they can range from a low-cost portable device that is often used for personal health monitoring to high-end sophisticated equipment that can only be operated by trained professionals. Depending on the functional purposes, there are different certification or compliance markings on the device when it is sold. One common certification marking is the Conformité Européenne affixation but this has a range of certification mark numbering for a variety of functional purposes. While the regulators and medical device manufacturers understand the associated significance and clinical implications, these may not be apparent to the professionals (using or maintaining the device) and the general public. With portable healthcare devices and mobile applications gaining popularity, better awareness of certification marking will be needed. Particularly, there are differences in the allowed functional purposes and the associated cost derivations of devices with a seemingly similar nature. A preferred approach such as an easy-to-understand notation next to any certification marking on a device can aid in differentiation without the need to digest mountainous regulatory details.

  5. Bioinformatics for Next Generation Sequencing Data

    Directory of Open Access Journals (Sweden)

    Alberto Magi

    2010-09-01

    Full Text Available The emergence of next-generation sequencing (NGS platforms imposes increasing demands on statistical methods and bioinformatic tools for the analysis and the management of the huge amounts of data generated by these technologies. Even at the early stages of their commercial availability, a large number of softwares already exist for analyzing NGS data. These tools can be fit into many general categories including alignment of sequence reads to a reference, base-calling and/or polymorphism detection, de novo assembly from paired or unpaired reads, structural variant detection and genome browsing. This manuscript aims to guide readers in the choice of the available computational tools that can be used to face the several steps of the data analysis workflow.

  6. Next-generation DNA sequencing of HEXA: a step in the right direction for carrier screening

    Science.gov (United States)

    Hoffman, Jodi D; Greger, Valerie; Strovel, Erin T; Blitzer, Miriam G; Umbarger, Mark A; Kennedy, Caleb; Bishop, Brian; Saunders, Patrick; Porreca, Gregory J; Schienda, Jaclyn; Davie, Jocelyn; Hallam, Stephanie; Towne, Charles

    2013-01-01

    Tay-Sachs disease (TSD) is the prototype for ethnic-based carrier screening, with a carrier rate of ∼1/27 in Ashkenazi Jews and French Canadians. HexA enzyme analysis is the current gold standard for TSD carrier screening (detection rate ∼98%), but has technical limitations. We compared DNA analysis by next-generation DNA sequencing (NGS) plus an assay for the 7.6 kb deletion to enzyme analysis for TSD carrier screening using 74 samples collected from participants at a TSD family conference. Fifty-one of 74 participants had positive enzyme results (46 carriers, five late-onset Tay-Sachs [LOTS]), 16 had negative, and seven had inconclusive results. NGS + 7.6 kb del screening of HEXA found a pathogenic mutation, pseudoallele, or variant of unknown significance (VUS) in 100% of the enzyme-positive or obligate carrier/enzyme-inconclusive samples. NGS detected the B1 allele in two enzyme-negative obligate carriers. Our data indicate that NGS can be used as a TSD clinical carrier screening tool. We demonstrate that NGS can be superior in detecting TSD carriers compared to traditional enzyme and genotyping methodologies, which are limited by false-positive and false-negative results and ethnically focused, limited mutation panels, respectively, but is not ready for sole use due to lack of information regarding some VUS. PMID:24498621

  7. Next Steps in Attachment Theory.

    Science.gov (United States)

    Bell, David C

    2012-12-01

    Thanks to the phenomenal success of attachment theory, great progress has been made in understanding child and adult relationships. The success of attachment theory opens the way to new research directions that can extend its successes even further. In particular, more work on the fundamental nature of attachment that respects recent biological research is important, as is concentrated effort on the related caregiving system.

  8. Next Steps in Attachment Theory

    OpenAIRE

    Bell, David C.

    2012-01-01

    Thanks to the phenomenal success of attachment theory, great progress has been made in understanding child and adult relationships. The success of attachment theory opens the way to new research directions that can extend its successes even further. In particular, more work on the fundamental nature of attachment that respects recent biological research is important, as is concentrated effort on the related caregiving system.

  9. Project control - the next generation

    International Nuclear Information System (INIS)

    Iorii, V.F.; McKinnon, B.L.

    1993-01-01

    The Yucca Mountain Site Characterization Project (YMP) is the U.S. Department of Energy's (DOE) second largest Major System Acquisition Project. We have developed an integrated planning and control system (called PACS) that we believe represents the 'Next Generation' in project control. PACS integrates technical scope, cost, and schedule information for over 50 participating organizations and produces performances measurement reports for science and engineering managers at all levels. Our 'Next Generation' project control too, PACS, has been found to be in compliance with the new DOE Project Control System Guidelines. Additionally, the nuclear utility oversight group of the Edison Electric Institute has suggested PACS be used as a model for other civilian radioactive waste management projects. A 'Next Generation' project control tool will be necessary to do science in the 21st century

  10. To Classify Spontaneous Motion Intention of Step Size by Using Cerebral Hemoglobin Information

    Directory of Open Access Journals (Sweden)

    Zhu Kai

    2017-01-01

    Full Text Available To improve the effect of walking-assistive devices, there is a need for it to develop devices controlled by spontaneous intention of patients. In recent study, we identified spontaneous motion intention of walking step based on cerebral hemoglobin information. Twenty healthy subjects performed walking tasks in three levels of step size (small, normal and large. According to distribution features of signals’ power spectral-density, six frequency bands (0-0.18Hz with an interval of 0.03Hz for each band width divided by applying wavelet packets decomposition were mainly analyzed. Feature vectors were extracted from the difference between oxygenated hemoglobin (oxyHb and deoxygenated hemoglobin (dexoyHb in different measuring channels in the six frequency bands. Support vector machine (SVM method was utilized to classify the three levels of step sizes. Mean recognition accuracy achieved up to 83.3%. The result indicated that it is possible to identify spontaneous walking by using cerebral hemoglobin information. This is helpful for enhancing the intelligence of walking-assistive devices and motivating the active control of patients, which further is profitable for enhancing self-confidence of patients.

  11. Thermonuclear device

    International Nuclear Information System (INIS)

    Yagi, Yasuomi; Takahashi, Ken; Hashimoto, Hiroshi.

    1984-01-01

    Purpose: To improve the plasma confining performances by bringing the irregular magnetic fields nearly to zero and decreasing the absolute value of the irregular magnetic fields at every positions. Constitution: The winding direction of a plurality of coil elements, for instance, double pan cake coils of toroidal coils in a torus type or mirror type thermonuclear device are reversed to each other in their laminating direction, whereby the irregular magnetic fields due to the coil-stepped portions in each toroidal coils are brought nearly to zero. This enables to bring the average irregular magnetic fields as a whole in the thermonuclear device nearly to zero, as well as, decrease the absolute value of the irregular magnetic fields in each positions. Thus, the plasma confining performances can be improved. (Moriyama, K.)

  12. Army Business Transformation - Next Steps

    National Research Council Canada - National Science Library

    2006-01-01

    As a follow-on to the Army Science Board 2005 Summer Study on Best Practices, the Army Science Board was tasked to identify areas where alternative approaches and application of transforming practices...

  13. ELGA and TOR installations control device to carry out experiments on-line with a mass-separator by the ASNAPP-2 code

    International Nuclear Information System (INIS)

    Arvai, Z.; Guyash, Ya.; Kuznetsov, V.V.; Fominykh, V.I.

    1984-01-01

    The control device of the tor beta-spectrometer with toroidal magnetic field and the ELGA spectrometer with semiconductor detectors for investigation of conversion electrons, positrons, γ- and α-radiations and lifetime of excited states and periods of isotopes half-decay are described. The block-diagram of the measurement processes, algorithm of the ELGA devce operation, control device circuit, and circuit for connection of analog-to-digital converter with the CAMAC dataway, block-diagram of step motor control, and step motor feeding scheme as well as mechanical and electrical characteristics of the step motor are given. The device is used for spectroscopic investigations of short-lived isotopes on the accelerator proton beam with mass separator

  14. Focused particle beam nano-machining: the next evolution step towards simulation aided process prediction

    International Nuclear Information System (INIS)

    Plank, Harald

    2015-01-01

    During the last decade, focused ion beam processing has been developed from traditionally used Ga + liquid ion sources towards higher resolution gas field ion sources (He + and Ne + ). Process simulations not only improve the fundamental understanding of the relevant ion–matter interactions, but also enable a certain predictive power to accelerate advances. The historic ‘gold’ standard in ion–solid simulations is the SRIM/TRIM Monte Carlo package released by Ziegler, Ziegler and Biersack 2010 Nucl. Instrum. Methods B 268 1818–23. While SRIM/TRIM is very useful for a myriad of applications, it is not applicable for the understanding of the nanoscale evolution associated with ion beam nano-machining as the substrate does not evolve with the sputtering process. As a solution for this problem, a new, adapted simulation code is briefly overviewed and finally addresses these contributions. By that, experimentally observed Ne + beam sputter profiles can be explained from a fundamental point of view. Due to their very good agreement, these simulations contain the potential for computer aided optimization towards predictable sputter processes for different nanotechnology applications. With these benefits in mind, the discussed simulation approach represents an enormous step towards a computer based master tool for adaptable ion beam applications in the context of industrial applications. (viewpoint)

  15. Integration in design and manufacturing of polymer smart devices

    NARCIS (Netherlands)

    Bolt, P.J.; Zwart, R.M. de; Tacken, R.A.; Rendering, H.

    2009-01-01

    Integration of functions in single components is pursued in order to manufacture smaller and smarter polymer micro devices at less cost, through e.g. less assembly steps. It requires integration on both product and production side. This paper addresses the use of molded interconnect device (MID)

  16. A splitting scheme based on the space-time CE/SE method for solving multi-dimensional hydrodynamical models of semiconductor devices

    Science.gov (United States)

    Nisar, Ubaid Ahmed; Ashraf, Waqas; Qamar, Shamsul

    2016-08-01

    Numerical solutions of the hydrodynamical model of semiconductor devices are presented in one and two-space dimension. The model describes the charge transport in semiconductor devices. Mathematically, the models can be written as a convection-diffusion type system with a right hand side describing the relaxation effects and interaction with a self consistent electric field. The proposed numerical scheme is a splitting scheme based on the conservation element and solution element (CE/SE) method for hyperbolic step, and a semi-implicit scheme for the relaxation step. The numerical results of the suggested scheme are compared with the splitting scheme based on Nessyahu-Tadmor (NT) central scheme for convection step and the same semi-implicit scheme for the relaxation step. The effects of various parameters such as low field mobility, device length, lattice temperature and voltages for one-space dimensional hydrodynamic model are explored to further validate the generic applicability of the CE/SE method for the current model equations. A two dimensional simulation is also performed by CE/SE method for a MESFET device, producing results in good agreement with those obtained by NT-central scheme.

  17. Insertion devices and beamlines for the proposed Australian synchrotron light source

    International Nuclear Information System (INIS)

    Garrett, R.F.; Boldeman, J.W.

    1999-01-01

    Full text: The proposed Australian synchrotron light source, Boomerang, is a third generation 3 GeV storage ring which is designed to provide for the great majority of Australian requirements for synchrotron radiation well into the next century. The storage ring could accommodate up to 60 experimental stations, including beamlines from 9 insertion devices, which far exceeds the projected Australian requirements over the life of the facility. Undulator radiation will be available up to 20 keV. The first phase construction of Boomerang includes funding for 9 beamlines, comprising 5 bending magnet and 4 insertion device beamlines. The beamline complement has been chosen to cater for approximately 95% of the current and projected Australian demand for synchrotron radiation over the first 5 years operation of the facility. Details will be shown of the performance of the proposed insertion devices, and the initial beamline complement will be presented

  18. Neutron matter at next-to-next-to-next-to-leading order in chiral effective field theory.

    Science.gov (United States)

    Tews, I; Krüger, T; Hebeler, K; Schwenk, A

    2013-01-18

    Neutron matter presents a unique system for chiral effective field theory because all many-body forces among neutrons are predicted to next-to-next-to-next-to-leading order (N(3)LO). We present the first complete N(3)LO calculation of the neutron matter energy. This includes the subleading three-nucleon forces for the first time and all leading four-nucleon forces. We find relatively large contributions from N(3)LO three-nucleon forces. Our results provide constraints for neutron-rich matter in astrophysics with controlled theoretical uncertainties.

  19. Software test attacks to break mobile and embedded devices

    CERN Document Server

    Hagar, Jon Duncan

    2013-01-01

    Address Errors before Users Find Them Using a mix-and-match approach, Software Test Attacks to Break Mobile and Embedded Devices presents an attack basis for testing mobile and embedded systems. Designed for testers working in the ever-expanding world of ""smart"" devices driven by software, the book focuses on attack-based testing that can be used by individuals and teams. The numerous test attacks show you when a software product does not work (i.e., has bugs) and provide you with information about the software product under test. The book guides you step by step starting with the basics. It

  20. Understanding Collateral Evolution in Linux Device Drivers

    DEFF Research Database (Denmark)

    Padioleau, Yoann; Lawall, Julia Laetitia; Muller, Gilles

    2006-01-01

    no tools to help in this process, collateral evolution is thus time consuming and error prone.In this paper, we present a qualitative and quantitative assessment of collateral evolution in Linux device driver code. We provide a taxonomy of evolutions and collateral evolutions, and use an automated patch......-analysis tool that we have developed to measure the number of evolutions and collateral evolutions that affect device drivers between Linux versions 2.2 and 2.6. In particular, we find that from one version of Linux to the next, collateral evolutions can account for up to 35% of the lines modified in such code....

  1. Step dynamics and terrace-width distribution on flame-annealed gold films: The effect of step-step interaction

    International Nuclear Information System (INIS)

    Shimoni, Nira; Ayal, Shai; Millo, Oded

    2000-01-01

    Dynamics of atomic steps and the terrace-width distribution within step bunches on flame-annealed gold films are studied using scanning tunneling microscopy. The distribution is narrower than commonly observed for vicinal planes and has a Gaussian shape, indicating a short-range repulsive interaction between the steps, with an apparently large interaction constant. The dynamics of the atomic steps, on the other hand, appear to be influenced, in addition to these short-range interactions, also by a longer-range attraction of steps towards step bunches. Both types of interactions promote self-ordering of terrace structures on the surface. When current is driven through the films a step-fingering instability sets in, reminiscent of the Bales-Zangwill instability

  2. The environmental interactions of tidal and wave energy generation devices

    OpenAIRE

    Frid, C.; Andonegi, E.; Depestele, J.; Judd, A.; Rihan, D.; Rogers, S.I.; Kenchington, E.

    2012-01-01

    Global energy demand continues to grow and tidal and wave energy generation devices can provide a significant source of renewable energy. Technological developments in offshore engineering and the rising cost of traditional energy means that offshore energy resources will be economic in the next few years. While there is now a growing body of data on the ecological impacts of offshore wind farms, the scientific basis on which to make informed decisions about the environmental effects of other...

  3. A bibliometric analysis of the development of next generation active nanotechnologies

    International Nuclear Information System (INIS)

    Suominen, Arho; Li, Yin; Youtie, Jan; Shapira, Philip

    2016-01-01

    Delineating the emergence of nanotechnologies that offer new functionalities is an important element in an anticipatory approach to the governance of nanotechnology and its potential impacts. This paper examines the transition to next generation active nanotechnologies which incorporate functions that respond to the environment or systems concepts that combine devices and structures that are dynamic and which may change their states in use. We develop an approach to identifying these active nanotechnologies and then use bibliometric analysis to examine the extent of research papers and patents involving these concepts. We also examine references to environmental, health, and safety concepts in these papers, given that these next generation nanotechnologies are likely to have risk profiles that are different from those of first-generation passive nanomaterials. Our results show a steady growth overall in focus on active nanotechnologies in the research literature and in patents over the study period of 1990–2010. We also find an increase in consideration given to environmental, health, and safety topics. While gaps are highlighted in our understanding of research and innovation in active nanotechnologies, the results suggest that there is beginning to be a shift to active nanotechnologies, with the implication that governance processes need to be conscious of this shift and to prepare for it.

  4. A bibliometric analysis of the development of next generation active nanotechnologies

    Energy Technology Data Exchange (ETDEWEB)

    Suominen, Arho [VTT Technical Research Centre of Finland (Finland); Li, Yin; Youtie, Jan, E-mail: jan.youtie@innovate.gatech.edu; Shapira, Philip [Georgia Institute of Technology (United States)

    2016-09-15

    Delineating the emergence of nanotechnologies that offer new functionalities is an important element in an anticipatory approach to the governance of nanotechnology and its potential impacts. This paper examines the transition to next generation active nanotechnologies which incorporate functions that respond to the environment or systems concepts that combine devices and structures that are dynamic and which may change their states in use. We develop an approach to identifying these active nanotechnologies and then use bibliometric analysis to examine the extent of research papers and patents involving these concepts. We also examine references to environmental, health, and safety concepts in these papers, given that these next generation nanotechnologies are likely to have risk profiles that are different from those of first-generation passive nanomaterials. Our results show a steady growth overall in focus on active nanotechnologies in the research literature and in patents over the study period of 1990–2010. We also find an increase in consideration given to environmental, health, and safety topics. While gaps are highlighted in our understanding of research and innovation in active nanotechnologies, the results suggest that there is beginning to be a shift to active nanotechnologies, with the implication that governance processes need to be conscious of this shift and to prepare for it.

  5. 1st International Conference on Intelligent Computing, Communication and Devices

    CERN Document Server

    Patnaik, Srikanta; Ichalkaranje, Nikhil

    2015-01-01

    In the history of mankind, three revolutions which impact the human life are the tool-making revolution, agricultural revolution and industrial revolution. They have transformed not only the economy and civilization but the overall development of the society. Probably, intelligence revolution is the next revolution, which the society will perceive in the next 10 years. ICCD-2014 covers all dimensions of intelligent sciences, i.e. Intelligent Computing, Intelligent Communication and Intelligent Devices. This volume covers contributions from Intelligent Communication which are from the areas such as Communications and Wireless Ad Hoc & Sensor Networks, Speech & Natural Language Processing, including Signal, Image and Video Processing and Mobile broadband and Optical networks, which are the key to the ground-breaking inventions to intelligent communication technologies. Secondly, Intelligent Device is any type of equipment, instrument, or machine that has its own computing capability. Contributions from ...

  6. Shortening User Interface Design Iterations through Realtime Visualisation of Design Actions on the Target Device

    OpenAIRE

    MESKENS, Jan; LUYTEN, Kris; CONINX, Karin

    2009-01-01

    In current mobile user interface design tools, it is time consuming to export a design to the target device. This makes it hard for designers to iterate over the user interfaces they are creating. We propose Gummy-live, a GUI builder for mobile devices allowing designers to test and observe immediately on the target device each step they take in the GUI builder. This way, designers are stimulated to iteratively test and refine user interface prototypes in order to take the target device charac...

  7. Single-fabrication-step Ge nanosphere/SiO2/SiGe heterostructures: a key enabler for realizing Ge MOS devices

    Science.gov (United States)

    Liao, P. H.; Peng, K. P.; Lin, H. C.; George, T.; Li, P. W.

    2018-05-01

    We report channel and strain engineering of self-organized, gate-stacking heterostructures comprising Ge-nanosphere gate/SiO2/SiGe-channels. An exquisitely-controlled dynamic balance between the concentrations of oxygen, Si, and Ge interstitials was effectively exploited to simultaneously create these heterostructures in a single oxidation step. Process-controlled tunability of the channel length (5–95 nm diameters for the Ge-nanospheres), gate oxide thickness (2.5–4.8 nm), as well as crystal orientation, chemical composition and strain engineering of the SiGe-channel was achieved. Single-crystalline (100) Si1‑x Ge x shells with Ge content as high as x = 0.85 and with a compressive strain of 3%, as well as (110) Si1‑x Ge x shells with Ge content of x = 0.35 and corresponding compressive strain of 1.5% were achieved. For each crystal orientation, our high Ge-content, highly-stressed SiGe shells feature a high degree of crystallinity and thus, provide a core ‘building block’ required for the fabrication of Ge-based MOS devices.

  8. Next-to-next-to-leading logarithms in four-fermion electroweak processes at high energy

    International Nuclear Information System (INIS)

    Kuehn, J.H.; Moch, S.; Penin, A.A.; Smirnov, V.A.

    2001-01-01

    We sum up the next-to-next-to-leading logarithmic virtual electroweak corrections to the high energy asymptotics of the neutral current four-fermion processes for light fermions to all orders in the coupling constants using the evolution equation approach. From this all order result we derive finite order expressions through next-to-next-to leading order for the total cross section and various asymmetries. We observe an amazing cancellation between the sizable leading, next-to-leading and next-to-next-to-leading logarithmic contributions at TeV energies

  9. Use of Diels-Alder Chemistry for Thermoreversible Cross-Linking of Rubbers : The Next Step toward Recycling of Rubber Products?

    NARCIS (Netherlands)

    Polgar, L. M.; van Duin, M.; Broekhuis, A. A.; Picchioni, F.

    2015-01-01

    A proof of principle for the use of Diels-Alder chemistry as a thermoreversible cross-linking tool for rubber products is demonstrated. A commercial ethylene-propylene rubber grafted with maleic anhydride has been thermoreversibly cross-linked in two steps. The pending anhydride rings were first

  10. The NIST Step Class Library (Step Into the Future)

    Science.gov (United States)

    1990-09-01

    Figure 6. Excerpt from a STEP exclange file based on the Geometry model 1be NIST STEP Class Libary Page 13 An issue of concern in this...Scheifler, R., Gettys, J., and Newman, P., X Window System: C Library and Protocol Reference. Digital Press, Bedford, Mass, 1988. [Schenck90] Schenck, D

  11. Numerical characterisation of one-step and three-step solar air heating collectors used for cocoa bean solar drying.

    Science.gov (United States)

    Orbegoso, Elder Mendoza; Saavedra, Rafael; Marcelo, Daniel; La Madrid, Raúl

    2017-12-01

    In the northern coastal and jungle areas of Peru, cocoa beans are dried using artisan methods, such as direct exposure to sunlight. This traditional process is time intensive, leading to a reduction in productivity and, therefore, delays in delivery times. The present study was intended to numerically characterise the thermal behaviour of three configurations of solar air heating collectors in order to determine which demonstrated the best thermal performance under several controlled operating conditions. For this purpose, a computational fluid dynamics model was developed to describe the simultaneous convective and radiative heat transfer phenomena under several operation conditions. The constructed computational fluid dynamics model was firstly validated through comparison with the data measurements of a one-step solar air heating collector. We then simulated two further three-step solar air heating collectors in order to identify which demonstrated the best thermal performance in terms of outlet air temperature and thermal efficiency. The numerical results show that under the same solar irradiation area of exposition and operating conditions, the three-step solar air heating collector with the collector plate mounted between the second and third channels was 67% more thermally efficient compared to the one-step solar air heating collector. This is because the air exposition with the surface of the collector plate for the three-step solar air heating collector former device was twice than the one-step solar air heating collector. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Pressure-driven one-step solid phase-based on-chip sample preparation on a microfabricated plastic device and integration with flow-through polymerase chain reaction (PCR).

    Science.gov (United States)

    Tran, Hong Hanh; Trinh, Kieu The Loan; Lee, Nae Yoon

    2013-10-01

    In this study, we fabricate a monolithic poly(methylmethacrylate) (PMMA) microdevice on which solid phase-based DNA preparation and flow-through polymerase chain reaction (PCR) units were functionally integrated for one-step sample preparation and amplification operated by pressure. Chelex resin, which is used as a solid support for DNA preparation, can capture denatured proteins but releases DNA, and the purified DNA can then be used as a template in a subsequent amplification process. Using the PMMA microdevices, DNA was successfully purified from both Escherichia coli and human hair sample, and the plasmid vector inserted in E. coli and the D1S80 locus in human genomic DNA were successfully amplified from on-chip purified E. coli and human hair samples. Furthermore, the integration potential of the proposed sample preparation and flow-through PCR units was successfully demonstrate on a monolithic PMMA microdevice with a seamless flow, which could pave the way for a pressure-driven, simple one-step sample preparation and amplification with greatly decreased manufacture cost and enhanced device disposability. Copyright © 2013 Elsevier B.V. All rights reserved.

  13. The effect of step height on the performance of three-dimensional ac electro-osmotic microfluidic pumps.

    Science.gov (United States)

    Urbanski, John Paul; Levitan, Jeremy A; Burch, Damian N; Thorsen, Todd; Bazant, Martin Z

    2007-05-15

    Recent numerical and experimental studies have investigated the increase in efficiency of microfluidic ac electro-osmotic pumps by introducing nonplanar geometries with raised steps on the electrodes. In this study, we analyze the effect of the step height on ac electro-osmotic pump performance. AC electro-osmotic pumps with three-dimensional electroplated steps are fabricated on glass substrates and pumping velocities of low ionic strength electrolyte solutions are measured systematically using a custom microfluidic device. Numerical simulations predict an improvement in pump performance with increasing step height, at a given frequency and voltage, up to an optimal step height, which qualitatively matches the trend observed in experiment. For a broad range of step heights near the optimum, the observed flow is much faster than with existing planar pumps (at the same voltage and minimum feature size) and in the theoretically predicted direction of the "fluid conveyor belt" mechanism. For small step heights, the experiments also exhibit significant flow reversal at the optimal frequency, which cannot be explained by the theory, although the simulations predict weak flow reversal at higher frequencies due to incomplete charging. These results provide insight to an important parameter for the design of nonplanar electro-osmotic pumps and clues to improve the fundamental theory of ACEO.

  14. SPAR-H Step-by-Step Guidance

    Energy Technology Data Exchange (ETDEWEB)

    W. J. Galyean; A. M. Whaley; D. L. Kelly; R. L. Boring

    2011-05-01

    This guide provides step-by-step guidance on the use of the SPAR-H method for quantifying Human Failure Events (HFEs). This guide is intended to be used with the worksheets provided in: 'The SPAR-H Human Reliability Analysis Method,' NUREG/CR-6883, dated August 2005. Each step in the process of producing a Human Error Probability (HEP) is discussed. These steps are: Step-1, Categorizing the HFE as Diagnosis and/or Action; Step-2, Rate the Performance Shaping Factors; Step-3, Calculate PSF-Modified HEP; Step-4, Accounting for Dependence, and; Step-5, Minimum Value Cutoff. The discussions on dependence are extensive and include an appendix that describes insights obtained from the psychology literature.

  15. SPAR-H Step-by-Step Guidance

    International Nuclear Information System (INIS)

    Galyean, W.J.; Whaley, A.M.; Kelly, D.L.; Boring, R.L.

    2011-01-01

    This guide provides step-by-step guidance on the use of the SPAR-H method for quantifying Human Failure Events (HFEs). This guide is intended to be used with the worksheets provided in: 'The SPAR-H Human Reliability Analysis Method,' NUREG/CR-6883, dated August 2005. Each step in the process of producing a Human Error Probability (HEP) is discussed. These steps are: Step-1, Categorizing the HFE as Diagnosis and/or Action; Step-2, Rate the Performance Shaping Factors; Step-3, Calculate PSF-Modified HEP; Step-4, Accounting for Dependence, and; Step-5, Minimum Value Cutoff. The discussions on dependence are extensive and include an appendix that describes insights obtained from the psychology literature.

  16. SPAR-H Step-by-Step Guidance

    Energy Technology Data Exchange (ETDEWEB)

    April M. Whaley; Dana L. Kelly; Ronald L. Boring; William J. Galyean

    2012-06-01

    Step-by-step guidance was developed recently at Idaho National Laboratory for the US Nuclear Regulatory Commission on the use of the Standardized Plant Analysis Risk-Human Reliability Analysis (SPAR-H) method for quantifying Human Failure Events (HFEs). This work was done to address SPAR-H user needs, specifically requests for additional guidance on the proper application of various aspects of the methodology. This paper overviews the steps of the SPAR-H analysis process and highlights some of the most important insights gained during the development of the step-by-step directions. This supplemental guidance for analysts is applicable when plant-specific information is available, and goes beyond the general guidance provided in existing SPAR-H documentation. The steps highlighted in this paper are: Step-1, Categorizing the HFE as Diagnosis and/or Action; Step-2, Rate the Performance Shaping Factors; Step-3, Calculate PSF-Modified HEP; Step-4, Accounting for Dependence, and; Step-5, Minimum Value Cutoff.

  17. Study of an automatized experimental device for the irradiation of a radioactive target

    International Nuclear Information System (INIS)

    Claverie, G.

    1996-01-01

    In order to solve the enigma of solar neutrinos, a team of physicians of the nuclear research center of Bordeaux-Gradignan and of the center of nuclear spectroscopy and mass spectroscopy of Orsay (France) decided to measure again the cross section of the beryllium-proton nuclear reaction at the lowest possible energies. This measurement requires the design of an automatized experimental device to irradiate in a specific way a beryllium target with an accelerated proton beam. The aim of this work is the study of such a device for an energy range of 800 to 300 KeV. This device comprises a particle multi-detector and a shutter for the irradiation of the target and the counting of the reaction products according to a programmable time sequence. The advantage of this setup is to allow an important bombardment of the target and to ensure its cooling. This device is automatically controlled thanks to a micro-controller, actuators (step motors and electrostatic deflector). It includes some beam diagnosis elements controlled by step motors and a target temperature monitoring system controlling a safety valve. The management of the experiment cell vacuum has led to the design of a vacuum monitor allowing the precise follow up of the vacuum and the control of the safety valves of the device. The nuclear instrumentation necessary to be implemented for this measurement is also presented. (J.S.)

  18. Influence of coating steps of perovskite on low-temperature amorphous compact TiO x upon the morphology, crystallinity, and photovoltaic property correlation in planar perovskite solar cells

    Science.gov (United States)

    Shahiduzzaman, Md.; Furumoto, Yoshikazu; Yamamoto, Kohei; Yonezawa, Kyosuke; Azuma, Yosuke; Kitamura, Michinori; Matsuzaki, Hiroyuki; Karakawa, Makoto; Kuwabara, Takayuki; Takahashi, Kohshin; Taima, Tetsuya

    2018-03-01

    The fabrication of high-efficiency solution-processable perovskite solar cells has been achieved using mesostructured films and compact titanium dioxide (TiO2) layers in a process that involves high temperatures and cost. Here, we present an efficient approach for fabricating chemical-bath-deposited, low-temperature, and low-cost amorphous compact TiO x -based planar heterojunction perovskite solar cells by one-step and two-step coatings of the perovskite layer. We also investigate the effect of the number of perovskite coating steps on the compact TiO x layer. The grazing incidence wide-angle X-ray scattering technique is used to clarify the relationship between morphology, crystallinity, and photovoltaic properties of the resulting devices. Analysis of the films revealed that one-step spin-coating of perovskite exhibited an enhancement of film quality and crystallization that correlates to photovoltaic performance 1.5 times higher than that of a two-step-coated device. Our findings show that the resulting morphology, crystallinity, and device performances are strongly dependent on the number of coating steps of the perovskite thin layer on the compact TiO x layer. This result is useful knowledge for the low-cost production of planar perovskite solar cells.

  19. Cost and schedule reduction for next-generation Candu

    International Nuclear Information System (INIS)

    Hopwood, J.M.; Yu, S.; Pakan, M.; Soulard, M.

    2002-01-01

    AECL has developed a suite of technologies for Candu R reactors that enable the next step in the evolution of the Candu family of heavy-water-moderated fuel-channel reactors. These technologies have been combined in the design for the Advanced Candu Reactor TM1 (ACRTM), AECL's next generation Candu power plant. The ACR design builds extensively on the existing Candu experience base, but includes innovations, in design and in delivery technology, that provide very substantial reductions in capital cost and in project schedules. In this paper, main features of next generation design and delivery are summarized, to provide the background basis for the cost and schedule reductions that have been achieved. In particular the paper outlines the impact of the innovative design steps for ACR: - Selection of slightly enriched fuel bundle design; - Use of light water coolant in place of traditional Candu heavy water coolant; - Compact core design with unique reactor physics benefits; - Optimized coolant and turbine system conditions. In addition to the direct cost benefits arising from efficiency improvement, and from the reduction in heavy water, the next generation Candu configuration results in numerous additional indirect cost benefits, including: - Reduction in number and complexity of reactivity mechanisms; - Reduction in number of heavy water auxiliary systems; - Simplification in heat transport and its support systems; - Simplified human-machine interface. The paper also describes the ACR approach to design for constructability. The application of module assembly and open-top construction techniques, based on Candu and other worldwide experience, has been proven to generate savings in both schedule durations and overall project cost, by reducing premium on-site activities, and by improving efficiency of system and subsystem assembly. AECL's up-to-date experience in the use of 3-D CADDS and related engineering tools has also been proven to reduce both engineering and

  20. Social-Aware Relay Selection for Cooperative Multicast Device-to-Device Communications

    Directory of Open Access Journals (Sweden)

    Francesco Chiti

    2017-12-01

    Full Text Available The increasing use of social networks such as Facebook, Twitter, and Instagram to share photos, video streaming, and music among friends has generated a huge increase in the amount of data traffic over wireless networks. This social behavior has triggered new communication paradigms such as device-to-device (D2D and relaying communication schemes, which are both considered as strong drivers for the next fifth-generation (5G cellular systems. Recently, the social-aware layer and its relationship to and influence on the physical communications layer have gained great attention as emerging focus points. We focus here on the case of relaying communications to pursue the multicast data dissemination to a group of users forming a social community through a relay node, according to the extension of the D2D mode to the case of device-to-many devices. Moreover, in our case, the source selects the device to act as the relay among different users of the multicast group by taking into account both the propagation link conditions and the relay social-trust level with the constraint of minimizing the end-to-end content delivery delay. An optimization procedure is also proposed in order to achieve the best performance. Finally, numerical results are provided to highlight the advantages of considering the impact of social level on the end-to-end delivery delay in the integrated social–physical network in comparison with the classical relay-assisted multicast communications for which the relay social-trust level is not considered.

  1. Ian Ingram: Next Animals

    DEFF Research Database (Denmark)

    2015-01-01

    Ian Ingram: Next Animals is an exhibition catalogue presenting research on the work by Ian Ingram in relation to his exhibition Next Animals at Nikolaj Kunsthal in 2015.......Ian Ingram: Next Animals is an exhibition catalogue presenting research on the work by Ian Ingram in relation to his exhibition Next Animals at Nikolaj Kunsthal in 2015....

  2. QuickRNASeq lifts large-scale RNA-seq data analyses to the next level of automation and interactive visualization.

    Science.gov (United States)

    Zhao, Shanrong; Xi, Li; Quan, Jie; Xi, Hualin; Zhang, Ying; von Schack, David; Vincent, Michael; Zhang, Baohong

    2016-01-08

    RNA sequencing (RNA-seq), a next-generation sequencing technique for transcriptome profiling, is being increasingly used, in part driven by the decreasing cost of sequencing. Nevertheless, the analysis of the massive amounts of data generated by large-scale RNA-seq remains a challenge. Multiple algorithms pertinent to basic analyses have been developed, and there is an increasing need to automate the use of these tools so as to obtain results in an efficient and user friendly manner. Increased automation and improved visualization of the results will help make the results and findings of the analyses readily available to experimental scientists. By combing the best open source tools developed for RNA-seq data analyses and the most advanced web 2.0 technologies, we have implemented QuickRNASeq, a pipeline for large-scale RNA-seq data analyses and visualization. The QuickRNASeq workflow consists of three main steps. In Step #1, each individual sample is processed, including mapping RNA-seq reads to a reference genome, counting the numbers of mapped reads, quality control of the aligned reads, and SNP (single nucleotide polymorphism) calling. Step #1 is computationally intensive, and can be processed in parallel. In Step #2, the results from individual samples are merged, and an integrated and interactive project report is generated. All analyses results in the report are accessible via a single HTML entry webpage. Step #3 is the data interpretation and presentation step. The rich visualization features implemented here allow end users to interactively explore the results of RNA-seq data analyses, and to gain more insights into RNA-seq datasets. In addition, we used a real world dataset to demonstrate the simplicity and efficiency of QuickRNASeq in RNA-seq data analyses and interactive visualizations. The seamless integration of automated capabilites with interactive visualizations in QuickRNASeq is not available in other published RNA-seq pipelines. The high degree

  3. Higgs production at next-to-next-to-leading order

    Indian Academy of Sciences (India)

    Instituut-Lorentz, University of Leiden, Leiden, The Netherlands. Abstract. We describe the calculation of inclusive Higgs boson production at hadronic colliders at next-to-next-to-leading order (NNLO) in perturbative quantum chromody- namics. We have used the technique developed in ref. [4]. Our results agree with those.

  4. WIMS-IST/DRAGON-IST side-step calculation of reactivity device and structural material incremental cross sections for Wolsong NPP Unit 1

    International Nuclear Information System (INIS)

    Dahmani, M.; McArthur, R.; Kim, B.G.; Kim, S.M.; Seo, H.-B.

    2008-01-01

    This paper describes the calculation of two-group incremental cross sections for all of the reactivity devices and incore structural materials for an RFSP-IST full-core model of Wolsong NPP Unit 1, in support of the conversion of the reference plant model to two energy groups. This is of particular interest since the calculation used the new standard 'side-step' approach, which is a three-dimensional supercell method that employs the Industry Standard Toolset (IST) codes DRAGON-IST and WIMS-IST with the ENDF/B-VI nuclear data library. In this technique, the macroscopic cross sections for the fuel regions and the device material specifications are first generated using the lattice code WIMS-IST with 89 energy groups. DRAGON-IST then uses this data with a standard supercell modelling approach for the three-dimensional calculations. Incremental cross sections are calculated for the stainless-steel adjuster rods (SS-ADJ), the liquid zone control units (LZCU), the shutoff rods (SOR), the mechanical control absorbers (MCA) and various structural materials, such as guide tubes, springs, locators, brackets, adjuster cables and support bars and the moderator inlet nozzle deflectors. Isotopic compositions of the Zircaloy-2, stainless steel and Inconel X-750 alloys in these items are derived from Wolsong NPP Unit 1 history dockets. Their geometrical layouts are based on applicable design drawings. Mid-burnup fuel with no moderator poison was assumed. The incremental cross sections and key aspects of the modelling are summarized in this paper. (author)

  5. The longitudinal offset technique for apodization of coupled resonator optical waveguide devices: concept and fabrication tolerance analysis.

    Science.gov (United States)

    Doménech, José David; Muñoz, Pascual; Capmany, José

    2009-11-09

    In this paper, a novel technique to set the coupling constant between cells of a coupled resonator optical waveguide (CROW) device, in order to tailor the filter response, is presented. The technique is demonstrated by simulation assuming a racetrack ring resonator geometry. It consists on changing the effective length of the coupling section by applying a longitudinal offset between the resonators. On the contrary, the conventional techniques are based in the transversal change of the distance between the ring resonators, in steps that are commonly below the current fabrication resolution step (nm scale), leading to strong restrictions in the designs. The proposed longitudinal offset technique allows a more precise control of the coupling and presents an increased robustness against the fabrication limitations, since the needed resolution step is two orders of magnitude higher. Both techniques are compared in terms of the transmission esponse of CROW devices, under finite fabrication resolution steps.

  6. High-Luminosity LHC moves to the next phase

    CERN Multimedia

    2015-01-01

    This week saw several meetings vital for the medium-term future of CERN.    From Monday to Wednesday, the Resource Review Board, RRB, that oversees resource allocation in the LHC experiments, had a series of meetings. Thursday then saw the close-out meeting for the Hi-Lumi LHC design study, which was partially funded by the European Commission. These meetings focused on the High Luminosity upgrade for the LHC, which responds to the top priority of the European Strategy for Particle Physics adopted by the CERN Council in 2013. This upgrade will transform the LHC into a facility for precision studies, the logical next step for the high-energy frontier of particle physics. It is a challenging upgrade, both for the LHC and the detectors. The LHC is already the highest luminosity hadron collider ever constructed, generating up to a billion collisions per second at the heart of the detectors. The High Luminosity upgrade will see that number rise by a factor of five from 2025. For the detectors...

  7. Future prospect 2012-2025 - How will our business change for the next 10 years -

    Science.gov (United States)

    Tanaka, Sakae

    2013-04-01

    The purpose of this lecture is to discuss about the "Future". How our business will change in the next 10 years? I believe the key is 3 mega-trends "Sustainability", "Cloud Computing" and "Life Innovation". With the development of social environment, the required business will change, too. The future would be invisible if you shut yourself up in your single industry. It is important to see various business fields horizontally, and recognize various key changes stereoscopically such as demographics, economy, technology, sense of value and lifestyle, when you develop mid-and-long term strategy. "Cloud" is silent, but the revolution of personal computing. It will bring the drastic changes in every industry. It will make "voice" and "moving image" possible to use as the interface to access your computer. Cloud computing will also make the client device more diversified and spread the application range widely. 15 years ago, the term "IT" was equivalent to "personal computer". Recently, it rather means to use smartphone and tablet device. In the next several years, TV and car-navigation system will be connected to broadband and it will become a part of personal computing. The meaning of personal computing is changing essentially year by year. In near future, the universe of computing will expand to the energy, medical and health-care, and agriculture etc. It passed only 20 years since we use "Computer" in a full scale operation. Recently, computer has start understanding our few words and talking in babble like a baby. The history of computing has just started.

  8. Top-quark decay at next-to-next-to-leading order in QCD.

    Science.gov (United States)

    Gao, Jun; Li, Chong Sheng; Zhu, Hua Xing

    2013-01-25

    We present the complete calculation of the top-quark decay width at next-to-next-to-leading order in QCD, including next-to-leading electroweak corrections as well as finite bottom quark mass and W boson width effects. In particular, we also show the first results of the fully differential decay rates for the top-quark semileptonic decay t → W(+)(l(+)ν)b at next-to-next-to-leading order in QCD. Our method is based on the understanding of the invariant mass distribution of the final-state jet in the singular limit from effective field theory. Our result can be used to study arbitrary infrared-safe observables of top-quark decay with the highest perturbative accuracy.

  9. Symplectic models for general insertion devices

    International Nuclear Information System (INIS)

    Wu, Y.; Forest, E.; Robin, D. S.; Nishimura, H.; Wolski, A.; Litvinenko, V. N.

    2001-01-01

    A variety of insertion devices (IDs), wigglers and undulators, linearly or elliptically polarized,are widely used as high brightness radiation sources at the modern light source rings. Long and high-field wigglers have also been proposed as the main source of radiation damping at next generation damping rings. As a result, it becomes increasingly important to understand the impact of IDs on the charged particle dynamics in the storage ring. In this paper, we report our recent development of a general explicit symplectic model for IDs with the paraxial ray approximation. High-order explicit symplectic integrators are developed to study real-world insertion devices with a number of wiggler harmonics and arbitrary polarizations

  10. Nuclear reactor technology: the next 50 years

    International Nuclear Information System (INIS)

    Sollychin, R.; Subki, H.; Adelfang, P.; Koshy, T.

    2013-01-01

    hybrid energy systems therefore have the potential to be a key solution to meet the energy needs of the emerging economies in the next few decades. In order to be operated as part of distributed hybrid energy systems, SMRs should be available in various power rating and be able to be engineered for multiple-applications. They should also be user-friendly, and able to be integrated easily with renewable energy systems as well as, if necessary, with adjacent energy application/storage systems. With these considerations, a number of special design requirements for SMR have been identified. The multiple-applications of the SMR may include provision of neutron utilization for industrial applications and research in the future, depending upon the needs in the region where they are built. The difference between a research reactor and such SMR may therefore become indistinct. In any case, operating and utilizing research reactor and small and/or prototype SMR can be taken as a first step in the preparation for a larger nuclear power program, as both the small nuclear systems and the large nuclear power systems require personnel with similar skills sets and the support of the same/similar infrastructure including regulatory body. A strive-for-excellence culture normally required for the operation of a large nuclear system should therefore be cultivated starting with the deployment of the small nuclear systems including the research reactors. Organization well-embedded with such culture put a strong emphasis on safety, health and environmental protection. They are disciplined and well-motivated to perform work systematically, according to plans and established procedures. They communicate effectively within the organization and with stakeholders, and have a continuous drive to improve quality. These considerations should be included in the design of SMRs and research reactors to be deployed in the next 50 years. (author)

  11. An electron cooling device in the one MeV energy region

    International Nuclear Information System (INIS)

    Busso, L.; Tecchio, L.; Tosello, F.

    1987-01-01

    The project of an electron cooling device at 700 KeV electron energy is reported. The single parts of the device is described in detail. Electron beam diagnostics and technical problems is discussed. The electron gun, the accelerating/decelerating column and the collector have been studied by menas of the Herrmannsfeldt's program and at present are under construction. The high voltage system and the electron cooling magnet are also under construction. Vacuum tests with both hot and cold cathodes have demonstrated that the vacuum requirements can be attained by the use of non-evaporable getter (NEG) pumps between gun, collector and the cooling region. Both kinds of diagnostic for longitudinal and transversal electron temperature measurements are in progress. A first prototype of the synchronous picj-up was successfully tested at CERN SPS. At present the diagnostic with laser beam is in preparation. During the next year the device will be assembled and the laboratory test will be started

  12. Rucio, the next-generation Data Management system in ATLAS

    Science.gov (United States)

    Serfon, C.; Barisits, M.; Beermann, T.; Garonne, V.; Goossens, L.; Lassnig, M.; Nairz, A.; Vigne, R.; ATLAS Collaboration

    2016-04-01

    Rucio is the next-generation of Distributed Data Management (DDM) system benefiting from recent advances in cloud and ;Big Data; computing to address HEP experiments scaling requirements. Rucio is an evolution of the ATLAS DDM system Don Quixote 2 (DQ2), which has demonstrated very large scale data management capabilities with more than 160 petabytes spread worldwide across 130 sites, and accesses from 1,000 active users. However, DQ2 is reaching its limits in terms of scalability, requiring a large number of support staff to operate and being hard to extend with new technologies. Rucio addresses these issues by relying on new technologies to ensure system scalability, cover new user requirements and employ new automation framework to reduce operational overheads. This paper shows the key concepts of Rucio, details the Rucio design, and the technology it employs, the tests that were conducted to validate it and finally describes the migration steps that were conducted to move from DQ2 to Rucio.

  13. Rucio, the next-generation Data Management system in ATLAS

    CERN Document Server

    Serfon, C; Beermann, T; Garonne, V; Goossens, L; Lassnig, M; Nairz, A; Vigne, R

    2016-01-01

    Rucio is the next-generation of Distributed Data Management (DDM) system benefiting from recent advances in cloud and "Big Data" computing to address HEP experiments scaling requirements. Rucio is an evolution of the ATLAS DDM system Don Quijote 2 (DQ2), which has demonstrated very large scale data management capabilities with more than 160 petabytes spread worldwide across 130 sites, and accesses from 1,000 active users. However, DQ2 is reaching its limits in terms of scalability, requiring a large number of support staff to operate and being hard to extend with new technologies. Rucio addresses these issues by relying on new technologies to ensure system scalability, cover new user requirements and employ new automation framework to reduce operational overheads. This paper shows the key concepts of Rucio, details the Rucio design, and the technology it employs, the tests that were conducted to validate it and finally describes the migration steps that were conducted to move from DQ2 to Rucio.

  14. What Is Web 2.0: Design Patterns and Business Models for the Next Generation of Software

    OpenAIRE

    O'Reilly, Tim

    2007-01-01

    This paper was the first initiative to try to define Web2.0 and understand its implications for the next generation of software, looking at both design patterns and business modes. Web 2.0 is the network as platform, spanning all connected devices; Web 2.0 applications are those that make the most of the intrinsic advantages of that platform: delivering software as a continually-updated service that gets better the more people use it, consuming and remixing data from multiple sources, includi...

  15. Cognitive processing for step precision increases beta and gamma band modulation during overground walking

    DEFF Research Database (Denmark)

    Oliveira, Anderson Souza; Arguissain, Federico Gabriel; Andersen, Ole Kæseler

    2018-01-01

    The aim of this study was to investigate whether cognitive processing for defining step precision during walking could induce changes in electrocortical activity. Ten healthy adults (21-36 years) were asked to walk overground in three different conditions: (1) normal walking in a straight path (N...... activity in cognitive, motor and sensorimotor areas may be relevant to produce patterned and safe locomotion through challenging paths.......The aim of this study was to investigate whether cognitive processing for defining step precision during walking could induce changes in electrocortical activity. Ten healthy adults (21-36 years) were asked to walk overground in three different conditions: (1) normal walking in a straight path (NW....../sensorimotor regions, a phase in the gait cycle in which participants define the correct foot placement for the next step. These results suggest that greater cognitive demands during precision stepping influences electrocortical dynamics especially towards step transitions. Therefore, increased electrocortical...

  16. A factorization approach to next-to-leading-power threshold logarithms

    Energy Technology Data Exchange (ETDEWEB)

    Bonocore, D. [Nikhef,Science Park 105, NL-1098 XG Amsterdam (Netherlands); Laenen, E. [Nikhef,Science Park 105, NL-1098 XG Amsterdam (Netherlands); ITFA, University of Amsterdam,Science Park 904, Amsterdam (Netherlands); ITF, Utrecht University,Leuvenlaan 4, Utrecht (Netherlands); Magnea, L. [Dipartimento di Fisica, Università di Torino and INFN, Sezione di Torino,Via P. Giuria 1, I-10125, Torino (Italy); Melville, S. [School of Physics and Astronomy, University of Glasgow,Glasgow, G12 8QQ (United Kingdom); Vernazza, L. [Higgs Centre for Theoretical Physics, School of Physics and Astronomy, University of Edinburgh,Edinburgh, EH9 3JZ, Scotland (United Kingdom); White, C.D. [School of Physics and Astronomy, University of Glasgow,Glasgow, G12 8QQ (United Kingdom)

    2015-06-03

    Threshold logarithms become dominant in partonic cross sections when the selected final state forces gluon radiation to be soft or collinear. Such radiation factorizes at the level of scattering amplitudes, and this leads to the resummation of threshold logarithms which appear at leading power in the threshold variable. In this paper, we consider the extension of this factorization to include effects suppressed by a single power of the threshold variable. Building upon the Low-Burnett-Kroll-Del Duca (LBKD) theorem, we propose a decomposition of radiative amplitudes into universal building blocks, which contain all effects ultimately responsible for next-to-leading-power (NLP) threshold logarithms in hadronic cross sections for electroweak annihilation processes. In particular, we provide a NLO evaluation of the radiative jet function, responsible for the interference of next-to-soft and collinear effects in these cross sections. As a test, using our expression for the amplitude, we reproduce all abelian-like NLP threshold logarithms in the NNLO Drell-Yan cross section, including the interplay of real and virtual emissions. Our results are a significant step towards developing a generally applicable resummation formalism for NLP threshold effects, and illustrate the breakdown of next-to-soft theorems for gauge theory amplitudes at loop level.

  17. Rapid, low cost prototyping of transdermal devices for personal healthcare monitoring

    Directory of Open Access Journals (Sweden)

    Sanjiv Sharma

    2017-04-01

    Full Text Available The next generation of devices for personal healthcare monitoring will comprise molecular sensors to monitor analytes of interest in the skin compartment. Transdermal devices based on microneedles offer an excellent opportunity to explore the dynamics of molecular markers in the interstitial fluid, however good acceptability of these next generation devices will require several technical problems associated with current commercially available wearable sensors to be overcome. These particularly include reliability, comfort and cost. An essential pre-requisite for transdermal molecular sensing devices is that they can be fabricated using scalable technologies which are cost effective.We present here a minimally invasive microneedle array as a continuous monitoring platform technology. Method for scalable fabrication of these structures is presented. The microneedle arrays were characterised mechanically and were shown to penetrate human skin under moderate thumb pressure. They were then functionalised and evaluated as glucose, lactate and theophylline biosensors. The results suggest that this technology can be employed in the measurement of metabolites, therapeutic drugs and biomarkers and could have an important role to play in the management of chronic diseases. Keywords: Microneedles, Minimally invasive sensors, Continuous glucose monitoring (CGM, Continuous lactate monitoring (CLM, Interstitial therapeutic drug monitoring (iTDM

  18. Temperature-modulated annealing of c-plane sapphire for long-range-ordered atomic steps

    International Nuclear Information System (INIS)

    Yatsui, Takashi; Kuribara, Kazunori; Sekitani, Tsuyoshi; Someya, Takao; Yoshimoto, Mamoru

    2016-01-01

    High-quality single-crystalline sapphire is used to prepare various semiconductors because of its thermal stability. Here, we applied the tempering technique, which is well known in the production of chocolate, to prepare a sapphire substrate. Surprisingly, we successfully realised millimetre-range ordering of the atomic step of the sapphire substrate. We also obtained a sapphire atomic step with nanometre-scale uniformity in the terrace width and atomic-step height. Such sapphire substrates will find applications in the preparation of various semiconductors and devices. (paper)

  19. Smallest Nanoelectronic with Atomic Devices with Precise Structures

    Science.gov (United States)

    Yamada, Toshishige

    2000-01-01

    Since its invention in 1948, the transistor has revolutionized our everyday life - transistor radios and TV's appeared in the early 1960s, personal computers came into widespread use in the mid-1980s, and cellular phones, laptops, and palm-sized organizers dominated the 1990s. The electronics revolution is based upon transistor miniaturization; smaller transistors are faster, and denser circuitry has more functionality. Transistors in current generation chips are 0.25 micron or 250 nanometers in size, and the electronics industry has completed development of 0.18 micron transistors which will enter production within the next few years. Industry researchers are now working to reduce transistor size down to 0.13 micron - a thousandth of the width of a human hair. However, studies indicate that the miniaturization of silicon transistors will soon reach its limit. For further progress in microelectronics, scientists have turned to nanotechnology to advance the science. Rather than continuing to miniaturize transistors to a point where they become unreliable, nanotechnology offers the new approach of building devices on the atomic scale [see sidebar]. One vision for the next generation of miniature electronics is atomic chain electronics, where devices are composed of atoms aligned on top of a substrate surface in a regular pattern. The Atomic Chain Electronics Project (ACEP) - part of the Semiconductor Device Modeling and Nanotechnology group, Integrated Product Team at the NAS Facility has been developing the theory of understanding atomic chain devices, and the author's patent for atomic chain electronics is now pending.

  20. Quantifying Reliability - The Next Step for a Rapidly Maturing PV Industry and China's Role

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, Sarah

    2015-10-14

    PV customers wish to know how long their PV modules will last, but quantitatively predicting service life is difficult because of the large number of ways that a module can fail, the variability of the use environment, the cost of the testing, and the short product development time, especially when compared with the long desired lifetime. China should play a key role in developing international standards because China manufactures most of the world's PV modules. The presentation will describe the steps that need to be taken to create a service life prediction within the context of a defined bill of materials, process window and use environment. Worldwide standards for cost-effective approaches to service-life predictions will be beneficial to both PV customers and manufacturers since the consequences of premature module failure can be disastrous for both.

  1. Mobile and Wearable Device Features that Matter in Promoting Physical Activity.

    Science.gov (United States)

    Wang, Julie B; Cataldo, Janine K; Ayala, Guadalupe X; Natarajan, Loki; Cadmus-Bertram, Lisa A; White, Martha M; Madanat, Hala; Nichols, Jeanne F; Pierce, John P

    2016-07-01

    As wearable sensors/devices become increasingly popular to promote physical activity (PA), research is needed to examine how and which components of these devices people use to increase their PA levels. (1) To assess usability and level of engagement with the Fitbit One and daily SMS-based prompts in a 6-week PA intervention, and (2) to examine whether use/ level of engagement with specific intervention components were associated with PA change. Data were analyzed from a randomized controlled trial that compared (1) a wearable sensor/ device (Fitbit One) plus SMS-based PA prompts, and (2) Fitbit One only, among overweight/ obese adults (N = 67). We calculated average scores from Likert-type response items that assessed usability and level of engagement with device features (e.g., tracker, website, mobile app, and SMS-based prompts), and assessed whether such factors were associated with change in steps/day (using Actigraph GT3X+). Participants reported the Fitbit One was easy to use and the tracker helped to be more active. Those who used the Fitbit mobile app (36%) vs. those who did not (64%) had an increase in steps at 6-week follow-up, even after adjusting for previous web/app use: +545 steps/ day ( SE = 265) vs. -28 steps/ day ( SE = 242) ( p = .04). Level of engagement with the Fitbit One, particularly the mobile app, was associated with increased steps. Mobile apps can instantly display summaries of PA performance and could optimize self-regulation to activate change. More research is needed to determine whether such modalities might be cost-effective in future intervention research and practice.

  2. Fiscal 1999 research report. Development of ultralow- loss power device technology (Survey on next-generation practical power semiconductor devices); 1999 nendo choteisonshitsu denryoku soshi gijutsu kaihatsu seika hokokusho. Jisedai power handotai device jitsuyoka chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This research proposes the clear developmental policy and target for 'Development project of ultralow-loss power device technology' through the research on power electronics or advanced power semiconductor devices as key technology of conversion loss reduction for various power applications and power supply systems. Main research issues are as follows. A bidirectional current switch using P-MOS FETs is promising as an ace of power system interconnection control equipment. IEGT as MOS gate high-power device will be substituted for GTO gradually. SiC devices will play the leading part of low- loss power devices for inverters of power converters, power systems of electric vehicles, Shinkansen and maglev railways, power systems of information and communication systems, and DC power systems. Size and cost reduction of low-noise soft switching as application technology of power devices are possible by using active circuits. Development of high- efficiency low-noise compact inexpensive inverters is an important issue. Countermeasures against various losses of inverters are also described. (NEDO)

  3. Energy sources for the next 35-50 years

    International Nuclear Information System (INIS)

    Tollefson, E.

    1999-01-01

    The next 35-50 years will be a period of great change around the world with respect to energy resources. Problems such as global warming, the loss of forests, the growth of the population and the availability of energy in various forms will become more urgent and will have to be faced. There is a vocal group which raises doubts regarding the overall effects of adding carbon dioxide to the atmosphere in large quantities in terms of global warming and are therefore not taking seriously the commitments made at the 1992 Rio Summit on the Environment and Development. These attitudes need to be challenged. Forests continue to be destroyed in certain areas to provide farmland and fuel for 1.25 billion people. The need for a strong reforestation programme is evident. The world population now at 5.3 billion, continues to grow and is predicted to reach 8.3 billion by 2030. Where will the additional 3 billion people find living space, fuelwood and food? There is also the need for much more energy, but the emphasis needs to be on sources which are renewable so that global warming is not enhanced. There is steady progress being made in the development of photovoltaic sources, their costs closely approaching traditional generating methods. A rapid acceleration in the application of these devices in the next decade is to be expected. Wind power is playing a larger role and hydropower continues to provide a significant portion of society's needs for energy along with nuclear power. The relative amounts of the total energy 'pie' which will be required will depend on the availability of power from each of these sources and the political pressures brought to bear as a result of environmental, sociological and resource availability factors

  4. Thessaloniki's City Guide: a Tourist Site for Handheld Devices

    Science.gov (United States)

    Theodorou, Niki

    Mobile browsing is expected to become very popular during the next decade. Users will connect to the Internet and use a mobile browser as an every day tool, usually as a part of their mobile telephone. Many services that would be relevant for mobile use are location or time dependent such as: tourist information; maps; and train timetables. This paper describes step by step the production of the mobile tourist site of the city of Thessaloniki Greece. In the paper both the marketing strategies and the mobile site development techniques are included.

  5. Identification and Characterization of Key Human Performance Issues and Research in the Next Generation Air Transportation System (NextGen)

    Science.gov (United States)

    Lee, Paul U.; Sheridan, Tom; Poage, james L.; Martin, Lynne Hazel; Jobe, Kimberly K.

    2010-01-01

    This report identifies key human-performance-related issues associated with Next Generation Air Transportation System (NextGen) research in the NASA NextGen-Airspace Project. Four Research Focus Areas (RFAs) in the NextGen-Airspace Project - namely Separation Assurance (SA), Airspace Super Density Operations (ASDO), Traffic Flow Management (TFM), and Dynamic Airspace Configuration (DAC) - were examined closely. In the course of the research, it was determined that the identified human performance issues needed to be analyzed in the context of NextGen operations rather than through basic human factors research. The main gaps in human factors research in NextGen were found in the need for accurate identification of key human-systems related issues within the context of specific NextGen concepts and better design of the operational requirements for those concepts. By focusing on human-system related issues for individual concepts, key human performance issues for the four RFAs were identified and described in this report. In addition, mixed equipage airspace with components of two RFAs were characterized to illustrate potential human performance issues that arise from the integration of multiple concepts.

  6. Novel patternable and conducting metal-polymer nanocomposites: a step towards advanced mutlifunctional materials

    Science.gov (United States)

    Rodríguez-Cantó, Pedro J.; Martínez-Marco, Mariluz; Abargues, Rafael; Latorre-Garrido, Victor; Martínez-Pastor, Juan P.

    2013-03-01

    In this work, we present a novel patternable conducting nanocomposite containing gold nanoparticles. Here, the in-situ polymerization of 3T is carried out using HAuCl4 as oxidizing agent inside PMMA as host matrix. During the bake step, the gold salt is also reduced from Au(III) to Au(0) generating Au nanoparticles in the interpenetrating polymer network (IPN) system. We found that this novel multifunctional resist shows electrical conductivity and plasmonic properties as well as potential patterning capability provided by the host matrix. The resulting nanocomposite has been investigated by TEM and UV-Vis spectroscopy. Electrical characterization was also conducted for different concentration of 3T and Au(III) following a characteristic percolation behaviour. Conductivities values from 10-5 to 10 S/cm were successfully obtained depending on the IPN formulation. Moreover, The Au nanoparticles generated exhibited a localized surface plasmon resonance at around 520 nm. This synthetic approach is of potential application to modify the conductivity of numerous insulating polymers and synthesize Au nanoparticles preserving to some extent their physical and chemical properties. In addition, combination of optical properties (Plasmonics), electrical, and lithographic capability in the same material allows for the design of materials with novel functionalities and provides the basis for next generation devices.

  7. Methods of making microfluidic devices

    KAUST Repository

    Buttner, Ulrich

    2017-06-01

    Microfluidics has advanced in terms of designs and structures, however, fabrication methods are either time consuming or expensive to produce, in terms of the facilities and equipment needed. A fast and economically viable method is provided to allow, for example, research groups to have access to microfluidic fabrication. Unlike most fabrication methods, a method is provided to fabricate a microfluidic device in one step. In an embodiment, a resolution of 50 micrometers was achieved by using maskless high-resolution digital light projection (MDLP). Bonding and channel fabrication of complex or simple structures can be rapidly incorporated to fabricate the microfluidic devices.

  8. What Comes Next After a Successful Synthesis of a RP entity? USA Prospective

    International Nuclear Information System (INIS)

    Dence, Carmen S.

    2016-01-01

    The successful synthesis of a new RP is the first step - although a critical one- to what comes next: to make it available to a patient. This presentation will present an overview of the regulatory process in USA and how to blend the preclinical to translational research. The latter, then may become amenable to the much discussed 'personalized medicine', one of the goals for patient treatment. (author)

  9. Introduction of assistive devices: home nurses' practices and beliefs.

    Science.gov (United States)

    Roelands, Marc; Van Oost, Paulette; Depoorter, Anne Marie; Buysse, Ann; Stevens, Veerle

    2006-04-01

    This paper reports a study describing home nurses' intention and current practices regarding introducing assistive devices, and investigating whether their practice is related to social cognitive factors (attitudes, subjective norms and self-efficacy). Home nurses not only care for patients in particular medical domains, but also educate and guide them towards more independence. Patients with age-related disabilities in mobility and self-care might benefit from the use of assistive devices. A home nurse might be the first and only person to discuss the disability and use of an assistive device. Therefore, home nurses' beliefs about the introduction of assistive devices could affect their daily practices. A cross-sectional study was conducted with a convenience sample of 64 home nurses chosen from a random sample of home nursing departments. The home nurses completed a self-administered questionnaire. The Theory of Planned Behaviour framework was used to develop the social cognitive measures regarding each of the six steps distinguished in the introduction of assistive devices. Home nurses had positive attitudes and high levels of intention, subjective norm and self-efficacy towards most steps of the decision process to introduce assistive devices. In a multiple linear regression analysis, attitude and self-efficacy predicted intention to introduce assistive devices to older clients with disabilities. Intention was correlated to home nurses' current practices. The findings suggest that conditions are present to involve home nurses more explicitly in the introduction of assistive devices to their patients. Social cognitive factors should be taken into account when developing interventions that aim to support home nurses to do this.

  10. Reduced Order Models for Dynamic Behavior of Elastomer Damping Devices

    Science.gov (United States)

    Morin, B.; Legay, A.; Deü, J.-F.

    2016-09-01

    In the context of passive damping, various mechanical systems from the space industry use elastomer components (shock absorbers, silent blocks, flexible joints...). The material of these devices has frequency, temperature and amplitude dependent characteristics. The associated numerical models, using viscoelastic and hyperelastic constitutive behaviour, may become computationally too expensive during a design process. The aim of this work is to propose efficient reduced viscoelastic models of rubber devices. The first step is to choose an accurate material model that represent the viscoelasticity. The second step is to reduce the rubber device finite element model to a super-element that keeps the frequency dependence. This reduced model is first built by taking into account the fact that the device's interfaces are much more rigid than the rubber core. To make use of this difference, kinematical constraints enforce the rigid body motion of these interfaces reducing the rubber device model to twelve dofs only on the interfaces (three rotations and three translations per face). Then, the superelement is built by using a component mode synthesis method. As an application, the dynamic behavior of a structure supported by four hourglass shaped rubber devices under harmonic loads is analysed to show the efficiency of the proposed approach.

  11. Nuclear fusion power supply device

    International Nuclear Information System (INIS)

    Nakagawa, Satoshi.

    1975-01-01

    Object: To use a hybrid power supply device, which comprises a thyristor power supply and a diode power supply, to decrease cost of a nuclear fusion power supply device. Structure: The device comprises a thyristor power supply connected through a closing unit and a diode power supply connected in parallel through a breaker, input of each power supply being applied with an output voltage of a flywheel AC generator. When a current transformer is excited, a disconnecting switch is turned on to close the diode power supply and a current of the current transformer is increased by an automatic voltage regulator to a set value within a predetermined period of time. Next, the current is cut off by a breaker, and when the breaker is in on position, the disconnecting switch is opened to turn on the closing unit. Thus, when a plasma electric current reaches a predetermined value, the breaker is turned on, and the current of the current transformer is controlled by the thyristor power supply. (Kamimura, M.)

  12. The Value of Step-by-Step Risk Assessment for Unmanned Aircraft

    DEFF Research Database (Denmark)

    La Cour-Harbo, Anders

    2018-01-01

    The new European legislation expected in 2018 or 2019 will introduce a step-by-step process for conducting risk assessments for unmanned aircraft flight operations. This is a relatively simple approach to a very complex challenge. This work compares this step-by-step process to high fidelity risk...... modeling, and shows that at least for a series of example flight missions there is reasonable agreement between the two very different methods....

  13. Si-semiconductor device failure mechanisms

    International Nuclear Information System (INIS)

    Clauss, H.

    1976-12-01

    This report presents investigations on failure mechanisms that may cause defects during production and operation of silicon semiconductor devices. The failure analysis of aluminium metallization defects covers topics such as step coverage, dissolution pits and electromigration. Furthermore, the generation of process induced lattice defects was investigated. Improved processes avoiding those defects were developed. (orig.) [de

  14. Progress and Prospects in Stretchable Electroluminescent Devices

    Directory of Open Access Journals (Sweden)

    Wang Jiangxin

    2017-03-01

    Full Text Available Stretchable electroluminescent (EL devices are a new form of mechanically deformable electronics that are gaining increasing interests and believed to be one of the essential technologies for next generation lighting and display applications. Apart from the simple bending capability in flexible EL devices, the stretchable EL devices are required to withstand larger mechanical deformations and accommodate stretching strain beyond 10%. The excellent mechanical conformability in these devices enables their applications in rigorous mechanical conditions such as flexing, twisting, stretching, and folding.The stretchable EL devices can be conformably wrapped onto arbitrary curvilinear surface and respond seamlessly to the external or internal forces, leading to unprecedented applications that cannot be addressed with conventional technologies. For example, they are in demand for wide applications in biomedical-related devices or sensors and soft interactive display systems, including activating devices for photosensitive drug, imaging apparatus for internal tissues, electronic skins, interactive input and output devices, robotics, and volumetric displays. With increasingly stringent demand on the mechanical requirements, the fabrication of stretchable EL device is encountering many challenges that are difficult to resolve. In this review, recent progresses in the stretchable EL devices are covered with a focus on the approaches that are adopted to tackle materials and process challenges in stretchable EL devices and delineate the strategies in stretchable electronics. We first introduce the emission mechanisms that have been successfully demonstrated on stretchable EL devices. Limitations and advantages of the different mechanisms for stretchable EL devices are also discussed. Representative reports are reviewed based on different structural and material strategies. Unprecedented applications that have been enabled by the stretchable EL devices are

  15. Next-to-next-to-leading order QCD analysis of the revised CCFR data for xF3 structure function

    International Nuclear Information System (INIS)

    Kataev, A.L.; Kotikov, A.V.; Parente, G.; Sidorov, A.V.

    1997-01-01

    The results of the next-to-next-to-leading order QCD analysis of the recently revised experimental data of the CCFR collaboration for the xF 3 structure function using the Jacobi polynomial expansion method are presented. The effects of the higher twist contributions are included into the fits following the infrared renormalon motivated model. It is stressed that at the next-to-next-to-leading order the results for the parameter Λ M -bar S -bar (4) turn out to be almost nonsensitive to the predictions of the infrared renormalon model. The outcomes of our analysis are compared to the ones obtained by the CCFR collaboration itself at the next-to-leading order. (author)

  16. Comparison of real-time classification systems for arrhythmia detection on Android-based mobile devices.

    Science.gov (United States)

    Leutheuser, Heike; Gradl, Stefan; Kugler, Patrick; Anneken, Lars; Arnold, Martin; Achenbach, Stephan; Eskofier, Bjoern M

    2014-01-01

    The electrocardiogram (ECG) is a key diagnostic tool in heart disease and may serve to detect ischemia, arrhythmias, and other conditions. Automatic, low cost monitoring of the ECG signal could be used to provide instantaneous analysis in case of symptoms and may trigger the presentation to the emergency department. Currently, since mobile devices (smartphones, tablets) are an integral part of daily life, they could form an ideal basis for automatic and low cost monitoring solution of the ECG signal. In this work, we aim for a realtime classification system for arrhythmia detection that is able to run on Android-based mobile devices. Our analysis is based on 70% of the MIT-BIH Arrhythmia and on 70% of the MIT-BIH Supraventricular Arrhythmia databases. The remaining 30% are reserved for the final evaluation. We detected the R-peaks with a QRS detection algorithm and based on the detected R-peaks, we calculated 16 features (statistical, heartbeat, and template-based). With these features and four different feature subsets we trained 8 classifiers using the Embedded Classification Software Toolbox (ECST) and compared the computational costs for each classification decision and the memory demand for each classifier. We conclude that the C4.5 classifier is best for our two-class classification problem (distinction of normal and abnormal heartbeats) with an accuracy of 91.6%. This classifier still needs a detailed feature selection evaluation. Our next steps are implementing the C4.5 classifier for Android-based mobile devices and evaluating the final system using the remaining 30% of the two used databases.

  17. AugerNext: innovative research studies for the next generation ground-based ultra-high energy cosmic ray experiment

    Directory of Open Access Journals (Sweden)

    Haungs Andreas

    2013-06-01

    Full Text Available The findings so far of the Pierre Auger Observatory and also of the Telescope Array define the requirements for a possible next generation experiment: it needs to be considerably increased in size, it needs a better sensitivity to composition, and it should cover the full sky. AugerNext aims to perform innovative research studies in order to prepare a proposal fulfilling these demands. Such R&D studies are primarily focused in the following areas iconsolidation of the detection of cosmic rays using MHz radio antennas; iiproof-of-principle of cosmic-ray microwave detection; iiitest of the large-scale application of a new generation photo-sensors; ivgeneralization of data communication techniques; vdevelopment of new ways of muon detection with surface arrays. These AugerNext studies on new innovative detection methods for a next generation cosmic-ray experiment are performed at the Pierre Auger Observatory. The AugerNext consortium consists presently of fourteen partner institutions from nine European countries supported by a network of European funding agencies and it is a principal element of the ASPERA/ApPEC strategic roadmaps.

  18. A step-by-step translation of evidence into a psychosocial intervention for everyday activities in dementia: a focus group study.

    Science.gov (United States)

    Giebel, Clarissa M; Challis, David; Hooper, Nigel M; Ferris, Sally

    2018-03-01

    In order to increase the efficacy of psychosocial interventions in dementia, a step-by-step process translating evidence and public engagement should be adhered to. This paper describes such a process by involving a two-stage focus group with people with dementia (PwD), informal carers, and staff. Based on previous evidence, general aspects of effective interventions were drawn out. These were tested in the first stage of focus groups, one with informal carers and PwD and one with staff. Findings from this stage helped shape the intervention further specifying its content. In the second stage, participants were consulted about the detailed components. The extant evidence base and focus groups helped to identify six practical and situation-specific elements worthy of consideration in planning such an intervention, including underlying theory and personal motivations for participation. Carers, PwD, and staff highlighted the importance of rapport between practitioners and PwD prior to commencing the intervention. It was also considered important that the intervention would be personalised to each individual. This paper shows how valuable public involvement can be to intervention development, and outlines a process of public involvement for future intervention development. The next step would be to formally test the intervention.

  19. Quantum theory of novel parametric devices

    International Nuclear Information System (INIS)

    Drummond, P.D.; Reid, M.D.; Dechoum, K.; Chaturvedi, S.; Olsen, M.; Kheruntsyan, K.; Bradley, A.

    2005-01-01

    While the parametric amplifier is a widely used and important source of entangled and squeezed photons, there are many possible ways to investigate the physics of intracavity parametric devices. Novel quantum theory of parametric devices in this talk will cover several new types of unconventional devices, including the following topics:- Critical intracavity paramp - We calculate intrinsic limits to entanglement of a quantum paramp, caused by nonlinear effects originating in phase noise of the pump. - Degenerate planar paramp - We obtain universal quantum critical fluctuations in a planar paramp device by mapping to the equations of magnetic Lifshitz points Nondegenerate planar paramp - The Mermin-Wagner theorem is used to demonstrate that there is no phase transition in the case of a nondegenerate planar device - Coupled channel paramp - A robust and novel integrated entanglement source can be generated using type I waveguides coupled inside a cavity to generate spatial entanglement - Cascade paramps - This possible 'GHZ-type' source is obtained by cascading successive down conversion crystals inside the same cavity, giving two thresholds Parallel paramps - Tripartite entanglement can be generated if three intracavity paramp crystals are operated in parallel, each idler mode acting as a signal for the next. Finally, we briefly treat the relevant experimental developments. (author)

  20. Enhanced planar perovskite solar cell efficiency and stability using a perovskite/PCBM heterojunction formed in one step.

    Science.gov (United States)

    Zhou, Long; Chang, Jingjing; Liu, Ziye; Sun, Xu; Lin, Zhenhua; Chen, Dazheng; Zhang, Chunfu; Zhang, Jincheng; Hao, Yue

    2018-02-08

    Perovskite/PCBM heterojunctions are efficient for fabricating perovskite solar cells with high performance and long-term stability. In this study, an efficient perovskite/PCBM heterojunction was formed via conventional sequential deposition and one-step formation processes. Compared with conventional deposition, the one-step process was more facile, and produced a perovskite thin film of substantially improved quality due to fullerene passivation. Moreover, the resulting perovskite/PCBM heterojunction exhibited more efficient carrier transfer and extraction, and reduced carrier recombination. The perovskite solar cell device based on one-step perovskite/PCBM heterojunction formation exhibited a higher maximum PCE of 17.8% compared with that from the conventional method (13.7%). The device also showed exceptional stability, retaining 83% of initial PCE after 60 days of storage under ambient conditions.