WorldWideScience

Sample records for tf im kernkraftwerk

  1. Replacement of the feedwater pipe system in reactor building outside containment at the nuclear power plant Philippsburg; Austausch der Speisewasserleitung im Reaktorgebaeude ausserhalb SHB im Kernkraftwerk Philippsburg I

    Energy Technology Data Exchange (ETDEWEB)

    Kessler, A. [Energie-Versorgung Schwaben AG, Stuttgart (Germany); Labes, M. [Siemens AG Unternehmensbereich KWU, Offenbach am Main (Germany); Schwenk, B. [Kernkraftwerk Philippsburg GmbH (Germany)

    1998-11-01

    After full replacement of the feedwater pipe system during the inspection period in 1997, combined with a modern materials, manufacturing and analysis concept, the entire pipe system of the water/steam cycle in the reactor building of KKP 1 now consists of high-toughness materials. The safety level of the entire plant has been increased by leaving aside postulation of F2 breaks in the reactor building and providing for protection against 0.1 leaks. Based on fluid-dynamic calculations for the cases of pump failure and pipe break, as well as pipe system calculations in 5 extensive calculation cycles, about 130 documents were filed for inspection and approval (excluding preliminary test documents on restraints). Points of main interest for safety analysis in this context were the optimised closing performance of the 3rd check valves and the integrity of the nozzle region at the RPV. (oirg./CB) [Deutsch] Durch den Restaustausch der Speisewasserleitungen in der Revision 1997, verbunden mit einem modernen Werkstoff-, Fertigungs- und Nachweiskonzept, sind im Reaktorgebaeude von KKP 1 in den Hauptleitungen des Wasser-Dampf-Kreislaufes nur noch hochzaehe Werkstoffe eingesetzt. Durch den Verzicht auf das Postulat von 2F-Bruechen im Reaktorgebaeude und durch die Auslegung gegen 0,1F-Lecks wird das Sicherheitsniveau der Anlage insgesamt gesteigert. Ausgehend von fluiddynamischen Berechnungen fuer Pumpenausfall und Rohrbruch sowie Rohrsystem-Berechnungen in 5 umfangreichen Berechnungskreisen wurden fuer die Genehmigung und Begutachtung ca. 130 Unterlagen (ohne Halterungs-Vorpruefunterlagen) eingereicht und vom Gutachter geprueft. Schwerpunkte der Nachweisfuehrung waren die Optimierung des Schliessverhaltens der 3. Rueckschlagarmaturen sowie der Integritaetsnachweis des RDB-Anschlusses. (orig./MM)

  2. Sports fishers against Kernkraftwerk Grohnde: No success

    Energy Technology Data Exchange (ETDEWEB)

    1980-09-01

    With its decision of 18 July 1980, the Lueneburg Higher Administrative Court has dismissed the action of ten sport fishers' clubs against the decision of the Hanover Administrative Court of 2 June 1977 which had refused their application to re-establish the suspensive power of their actions against the enforceable first part-construction permit for Kernkraftwerk Grohnde on the Weser River. The Lueneburg Higher Administrative Court confirms the legality of the decision for immediate enforcement of nuclear construction permits as far as there is no irreparable damage to the rights of those concerned. The binding force of the decision concerning the site in the first part-construction permit is mentioned.

  3. Kernkraftwerk Brunsbuettel (KKB). Annual report 2001

    International Nuclear Information System (INIS)

    2002-04-01

    In the business year from 1 January through to 31 December 2001, Kernkraftwerk Brunsbuettel GmbH achieved a gross electric output of 6,010 GWh. The total net output transmitted to the two partner utilities Hamburger Electricitaets-Werke AG (HEW) and E.ON Kernkraft GmbH (E.ON KK) amounted to 5,764 GWh. Although the availability time ratio was 94.1 % (94.4 % previous year), the capacity factor was only 85.3 % (85.6 % previous year). This was due to postponement of the refuelling operation, spent fuel transports away from the reactor being delayed as a consequence of the political situation. The resulting considerable period of stretch-out operation with declining power output reduced the net output to 498 GWh. Otherwise, the capacity factor could have been 92.7 %. The short shutdown period of 23 days for power plant inspection inclusive of refuelling operation (20 days previous year) has had a positive impact on the operating data of the year 2001. The aggregate total gross electric output generated by the power station since it is operated by Kernkraftwerk Brunsbuettel GmbH amounts to 98,032 GWh. (orig./CB) [de

  4. Sports fishers against Kernkraftwerk Grohnde: No success

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    With its decision of 18 July 1980, the Lueneburg Higher Administrative Court has dismissed the action of ten sport fishers' clubs against the decision of the Hanover Administrative Court of June 2 June 1977 which had refused their application to re-establish the suspensive power of their actions against the enforceable first part-construction permit for Kernkraftwerk Grohnde on the Weser River. The Lueneburg Higher Administrative Court confirms the legality of the decision for immediate enforcement of nuclear construction permits as far as there is no irreparable damage to the rights of those concerned. The binding force of the decision concerning the site in the first part-construction permit is mentioned. (HSCH) [de

  5. Action of the city of Schweinfurt against Kernkraftwerk Grafenrheinfeld recognized

    International Nuclear Information System (INIS)

    Anon.

    1979-01-01

    In the appeal proceedings, the Bavarian Administrative Court with its interim decision of April 9, 1979 - No. 167 VI 74 - has recognized the action of the city of Schweinfurt against the state of Bavaria to set aside the 1st part license for the construction of Kernkraftwerk Grafenrheinfeld, although the right for action was limited to the city's legal position concerning planning authority, drinking water supply, and a city-owned lake used for swimming. Appeal was allowed. The city has lodged an appeal. The decision of the Administrative Court of Wuerzburg of March 25, 1977, which was contested by the appeal, had also recognized the city's rights but dismissed the action as being unfounded. Guidelines and reasons for the decision of the Bavarian Administrative Court are given in full wording. (orig./HP) 891 HP/orig.- 892 HIS [de

  6. Kernkraftwerke Lippe-Ems (KLE). 1997 annual report

    International Nuclear Information System (INIS)

    1998-01-01

    The Kernkraftwerke Lippe-Ems GmbH (KLE) is the operator of the Emsland reactor station at Lingen (Ems), equipped with a 1300 MW PWR. The partners of KLE are VEW ENERGIE, PreussenElektra, and RWE Energie. The nuclear power station was used over the reporting period as a base-load power plant operating under full-load conditions. The total gross electricity output was 11235 million kWh, which is the highest annual total output ever since start-up. The net electricity generation over the reporting amounted to 10650 million kWh. The personnel employed with KLE at the end of the reporting year amounts to 287. The reduction of the nominal capital of the GmbH to 900 000 TDM, decided by the partners in 1996, became legally effective in April 1997. The dominant features of the structure of expenses of KLE are expenses for the fuel inventory and spent fuel management, for the legally required reserves for decommissioning, and writeoffs. The contractual electric power rates negotiated with the partners cover all load and capacity-dependent expenses; in addition, the partners receive their contractual shares of the profit resulting from interests paid on the nominal capital. (orig./CB) [de

  7. Safety culture in nuclear power plants. Proceedings; Sicherheitskultur im Kernkraftwerk. Seminarbericht

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-01

    As a consequence of the INSAG-4 report on `safety culture`, published by the IAEA in 1991, the Federal Commission for the Safety of Nuclear Power Plants (KSA) decided to hold a one-day seminar as a first step in this field. The KSA is an advisory body of the Federal Government and the Federal Department of Transport and Energy (EVED). It comments on applications for licenses, observes the operation of nuclear power plants, assists with the preparation of regulations, monitors the progress of research in the field of nuclear safety, and makes proposals for research tasks. The objective of this seminar was to familiarise the participants with the principles of `safety culture`, with the experiences made in Switzerland and abroad with existing concepts, as well as to eliminate existing prejudices. The main points dealt with at this seminar were: - safety culture from the point of view of operators, - safety culture from the point of view of the authorities, - safety culture: collaboration between power plants, the authorities and research organisations, - trends and developments in the field of safety culture. Invitations to attend this seminar were extended to the management boards of companies operating Swiss nuclear power plants, and to representatives of the Swiss authorities responsible for the safety of nuclear power plants. All these organisations were represented by a large number of executive and specialist staff. We would like to express our sincerest thanks to the Head of the Federal Department of Transport and Energy for his kind patronage of this seminar. (author) figs., tabs., refs.

  8. Kernkraftwerke Lippe-Ems (KLE). Report on the business year 1994

    International Nuclear Information System (INIS)

    1995-01-01

    In the business year under report, Kernkraftwerk Emsland generated base load power and ran to capacity. Gross power generation was again enhanced as compared to the year previously, attaining the so far highest annual value with 11106 million kWh. Net power generation stood at 10526 million kWh in 1994. The expense structure of KLE is essentially determined by expenditure for fuel and fuel disposal, power plant decommissioning, and capital service. There were 287 staff. The report contains financial data. (orig./HP) [de

  9. Influence on components of EU directives; Einfluss von EG-Richtlinien auf Komponenten. Einfluss der EG-Druckgeraeterichtlinie (97/23/EG) auf die Komponenten eines Kernkraftwerks vom Typ Konvoi

    Energy Technology Data Exchange (ETDEWEB)

    Kreckel, D. [Siemens AG, Bereich Energieerzeugung (KWU), Offenbach (Germany)

    1998-11-01

    auch die nationale gesetzliche Struktur beeinflusst. Dabei gibt es auch Veraenderungen fuer die Konvoi-Kernkraftwerke bei den zutreffenden Gesetzen und Richtlinien, wie Atomgesetz, Gewerbeordnung und neuen Geraetesicherheitsgesetz mit Verordnungen sowie den zugeordneten Regeln der Sicherheitstechnik, wie KTA, AD, VdTUeV, VDI. Des weiteren unterliegen die allgemein anerkannten Regeln der Technik, wie DIN, SEL, SEW, einer permanenten europaeischen Harmonisierung und damit einer umfassenden nationalen Reorganisation. Um in diesem Umfeld zu bestehen, sind diese Randbedingungen bei der Anpassung der in den Betriebsgenehmigungen festgelegten Spezifikationen zum fortschreitenden Stand der Technik sorgfaeltig umzusetzen. Das darin festgelegte Anforderungsprofil muss mit der Genehmigungsbehoerde und dem zugezogenen Sachverstaendigen im Rahmen des Aufsichtsverfahrens fuer den Betrieb nach AtG auf die neue Situation in Deutschland (dominiert von Europa) ausgerichtet werden. Die hier fuer die modernen Konvoi-Kernkraftwerke beschriebene Situation ist auch auf die aelteren Kernkraftwerke zu uebertragen, muss allerdings der jeweiligen Genehmigungssituation ergaenzend angepasst werden. (orig.)

  10. Kernkraftwerk Sued - the Wyhl decision of March 30, 1982/July 6, 1982

    International Nuclear Information System (INIS)

    1982-01-01

    This volume contains the complete Wyhl decision of the Higher Administrative Court of Baden-Wuerttemberg of March 30, 1982-X575/77, X578/77, X583/77 which cores 548 pages. According to the press release the complete decision has been delivered to the counsels of the parties to the lawsuit on July 7, 1983; on the appeal of the defendant Land and the attending Kernkraftwerk Sued GmbH the Higher Administrative Court has amended the decisions of the Administrative Court of Freiburg of March 14, 1977 and has rejected the actions of nine citizens against the first part construction permit. Moreover, the senate has sent to the parties to the lawsuit the decision of March 30, 1982, by which the value in dispute for these proceedings on appeal is fixed to DM 180,000. The time for the lodging of an appeal, which has been admitted by the senate in this process, begins with the delivery of the completely well-founded decision. Moreover, the volume contains a 10 pages summary of contents of the decision and a table of contents of the reasons for the decision. (orig./HSCH) [de

  11. Muriithi, IM

    African Journals Online (AJOL)

    Muriithi, IM. Vol 8, No 2 (2014) - Articles Correlation of magnetic resonance imaging findings with arthroscopy in the evaluation of rotator cuff pathology. Abstract PDF · Vol 8, No 2 (2014) - Articles Patterns of knee, hip and hand osteoarthritis in Kenyatta National Hospital Abstract PDF. ISSN: 1994-1072. AJOL African ...

  12. Quick scan IMS vendors

    NARCIS (Netherlands)

    Norp, A.H.J.; Pals, H.; Walraven, F.A.

    2007-01-01

    IMS is gaining momentum in the market. First operators are deploying IMS, while other operators are considering buying IMS. Operators have two approaches for introducing IMS and building an IMS eco-system: • Buying IMS from a large vendor or system integrator. Vendors like Alcatel-Lucent, Ericsson

  13. Two-finger (TF) SPUDT cells.

    Science.gov (United States)

    Martin, Guenter; Biryukov, Sergey V; Schmidt, Hagen; Steiner, Bernd; Wall, Bert

    2011-03-01

    SPUDT cells including two fingers are only known thus far for so-called NSPUDT directions. In that case, usual solid-finger cells are used. The purpose of the present paper is to find SPUDT cell types consisting of two fingers only for pure mode directions. Two-finger (TF) cells for pure mode directions on substrates like 128°YX LiNbO(3) and YZ LiNbO(3) were found by means of an optimization procedure. The forward direction of a TF-cell SPUDT on 128°YX LiNbO(3) was determined experimentally. The properties of the new cells are compared with those of conventional SPUDT cells. The reflectivity of TF cells on 128°YX LiNbO(3) turns out to be two to three times larger than that of distributed acoustic reflection transducer (DART) and Hanma-Hunsinger cells at the same metal layer thickness.

  14. TfR Binding Peptide Screened by Phage Display Technology ...

    African Journals Online (AJOL)

    Purpose: To screen an hTfR affinity peptide and investigate its activity in vitro. Methods: hTfR ... Keywords: Peptide, hTfR, Transferrin receptor, Phage display technology, Enhanced green ..... mediated uptake of peptides that bind the human.

  15. Poolside fuel assembly inspection campaigns performed at Kernkraftwerk Leibstadt during summer 1997

    International Nuclear Information System (INIS)

    Zwicky, H.U.; Wiktor, C.G.; Schrire, D.

    1998-01-01

    In order to minimise fuel cycle costs, fuel assembly discharge burnup and average U-235 enrichment were increasing over past years in the Kernkraftwerk Leibstadt (KKL) plant. In parallel, high burnup verification programs were defined in collaboration with fuel suppliers. The aim of these programs is to demonstrate safe and reliable fuel performance up to the designed burnup limit and to identify any problems in due time. This is not only achieved by detailed poolside inspections of lead test assemblies, but also by hot cell post-irradiation examination of selected rods. In the frame of a hot cell examination campaign, enhanced localised corrosion in the vicinity of spacers on SVEA-96 fuel rods was identified in May 1997 as a potential problem. The average rod burnup of the investigated rods was around 50 MWd/kgU after 5 one year cycles of operation. As fuel operation up to six cycles is foreseen in KKLs fuel management plants, the risk of fuel failures caused by enhanced localised corrosion could not be excluded. An action plan was therefore developed in order to identify the root cause. Part of the action plan were two poolside inspection campaigns: 1. Visual inspection of 38 assemblies unloaded during refuelling outage 1996 after 5 cycles in operation. This campaign was performed in June 1997. It gave a broader data base to develop a concept for fuel management for the upcoming refuelling outage scheduled in August 1997. 2. Visual inspection, oxide layer thickness measurements, crud sampling and rod diameter measurements on 29 assemblies with different operation histories. This campaign was performed during the outage. A large portion of the inspected bundles was re-inserted for continued operation. The collected data confirmed that assumptions made for reload licensing and safety analyses were conservative. The inspection campaigns performed at KKL during summer 1997 by ABB Atom demonstrated that it is possible to address unexpected problems in a short time

  16. Analysis of NSTX TF Joint Voltage Measurements

    International Nuclear Information System (INIS)

    Woolley R

    2005-01-01

    This report presents findings of analyses of recorded current and voltage data associated with 72 electrical joints operating at high current and high mechanical stress. The analysis goal was to characterize the mechanical behavior of each joint and thus evaluate its mechanical supports. The joints are part of the toroidal field (TF) magnet system of the National Spherical Torus Experiment (NSTX) pulsed plasma device operating at the Princeton Plasma Physics Laboratory (PPPL). Since there is not sufficient space near the joints for much traditional mechanical instrumentation, small voltage probes were installed on each joint and their voltage monitoring waveforms have been recorded on sampling digitizers during each NSTX ''shot''

  17. Extending TF1: Argument parsing, function composition, and vectorization

    CERN Document Server

    Tsang Mang Kin, Arthur Leonard

    2017-01-01

    In this project, we extend the functionality of the TF1 function class in root. We add argument parsing, making it possible to freely pass variables and parameters into pre-defined and user-defined functions. We also introduce a syntax to use certain compositions of functions, namely normalized sums and convolutions, directly in TF1. Finally, we introduce some simple vectorization functionality to TF1 and demonstrate the potential to speed up parallelizable computations.

  18. Test facility for PLT TF coils

    International Nuclear Information System (INIS)

    Hearney, J.; File, J.; Dreskin, S.

    1975-01-01

    Past experience with the model C stellerator and other toroidal field devices indicates that mechanical and electrical tests of a toroidal field coil prior to maximum field operation of the device is prudent and desirable. This paper describes a test program for the PLT-TF coils. The test stand consists of one test coil, two background coils and a steel supporting structure. The three coil configuration produces a 67.5 kG field at the inner conductor (38 kG at the bore center) and simulates a 1/R field distribution in the bore of the test coil. The resolution of the field force system and resultant stresses within the test structure are discussed. A test procedure is described which maximizes the information obtained from a 100,000 pulse program

  19. Inductive Monitoring System (IMS)

    Data.gov (United States)

    National Aeronautics and Space Administration — IMS: Inductive Monitoring System The Inductive Monitoring System (IMS) is a tool that uses a data mining technique called clustering to extract models of normal...

  20. A-10/TF34 Turbine Engine Monitoring System (TEMS)

    Science.gov (United States)

    Christopher, R. G.

    1981-01-01

    The hardware and software development of the A-10/TF34 turbine engine monitoring system (TEMS) is described. The operation and interfaces of the A-10/TF34 TEMS hardware are discussed with particular emphasis on function, capabilities, and limitations. The TEMS data types are defined and the various data acquisition modes are explained. Potential data products are also discussed.

  1. Nuclear power plants in Germany. Recent developments in off-site nuclear emergency preparedness and response; Kernkraftwerke in Deutschland. Neue Entwicklungen im anlagenexternen Notfallschutz

    Energy Technology Data Exchange (ETDEWEB)

    Gering, Florian [Bundesamt fuer Strahlenschutz, Oberschleissheim/Neuherberg (Germany). Abt. SW 2.2 Entscheidungshilfesysteme, Lageermittlung und Kommunikation

    2014-10-15

    The reactor accident in Fukushima, Japan, in 2011 triggered a thorough review of the off-site emergency preparedness and response for nuclear power plants in Germany. ''Off-site emergency preparedness and response'' includes all actions to protect the public outside the fence of a nuclear power plant. This review resulted in several changes in off-site emergency preparedness and response, which are briefly described in this article. Additionally, several recent activities are described which may influence emergency preparedness and response in the future.

  2. Aspects of reactor dismantling planning following the safe entombment in the NPP Lingen (KWL); Aspekte der Abbauplanung nach dem Sicheren Einschluss im Kernkraftwerk Lingen (KWL)

    Energy Technology Data Exchange (ETDEWEB)

    Priesmeyer, U.; Rojahn, T.; Fries, B. [Kernkraftwerk Lingen GmbH (Germany)

    2009-07-01

    The NPP Lingen (KWL) was shut-down in 1977. Due to the fact that no final repository was available the safe entombment for 25 years was chosen following the decommissioning. The conventional plant components were dismantled and removed from the plant site. The licensing procedure for reactor dismantling with final disposal in Schacht Konrad has been started. The beginning of dismantling operation is scheduled for 2013. The authors describe the preparatory work, the boundary conditions for the dismantling, radiation protection considerations with respect to manual demolition work after the rather long decay time.

  3. Replacement of the cooling tower packing at the Goesgen-Daeniken AG nuclear power plant; Ersatz der Kuehlturmeinbauten im Kernkraftwerk Goesgen-Daeniken

    Energy Technology Data Exchange (ETDEWEB)

    Rich, Hans Walter [Kernkraftwerk Goesgen-Daeniken AG, Daeniken (Switzerland)

    2012-07-01

    In 2005 the asbestos cement cooling tower packing was replaced by plastic material. Two years later, the packing showed strong deformations, deposits of solids and weight gain. At the end of 2007 parts of the packing collapsed into the cooling tower basin. Investigations were made, revealing that the thickness of the packing foil was too low and that packing geometry and biofilms on the surface of the packing favoured deposition of solids. Successful measures were taken to solve the problems. (orig.)

  4. Bremssysteme im Personenkraftwagen

    Science.gov (United States)

    Reif, Konrad

    Für die ersten drei Punkte ist die Betriebsbremsanlage ("Fußbremse“) zuständig. Der Fahrer aktiviert sie durch Betätigen des Bremspedals. Die Feststellbremsanlage ("Handbremse“) hält das Fahrzeug im Stillstand.

  5. Geschlechterstereotype im Einsatz

    Directory of Open Access Journals (Sweden)

    Erika Kegyes

    2007-11-01

    Full Text Available Die umfangreiche Monographie gehört zum Forschungsbereich der kritischen angewandten Linguistik (Critical Applied Linguistics und liegt sowohl theoretisch als auch praktisch im Schnittpunkt der gender- und werbesprachlichen Untersuchungen.

  6. Tight aspect ratio tokamak power reactor with superconducting TF coils

    International Nuclear Information System (INIS)

    Nishio, S.; Tobita, K.; Konishi, S.; Ando, T.; Hiroki, S.; Kuroda, T.; Yamauchi, M.; Azumi, M.; Nagata, M.

    2003-01-01

    Tight aspect ratio tokamak power reactor with super-conducting toroidal field (TF) coils has been proposed. A center solenoid coil system and an inboard blanket were discarded. The key point was how to find the engineering design solution of the TF coil system with the high field and high current density. The coil system with the center post radius of less than 1 m can generate the maximum field of ∼ 20 T. This coil system causes a compact reactor concept, where the plasma major and minor radii of 3.75 m and 1.9 m, respectively and the fusion power of 1.8 GW. (author)

  7. Expression of antigen tf and galectin-3 in fibroadenoma.

    Science.gov (United States)

    Gallegos, Itandehui Belem; Pérez-Campos, Eduardo; Martinez, Margarito; Mayoral, Miguel Ángel; Pérez, Laura; Aguilar, Sergio; Zenteno, Edgar; Pina, Maria del Socorro; Hernández, Pedro

    2012-12-24

    Fibroadenomas are benign human breast tumors, characterized by proliferation of epithelial and stromal components of the terminal ductal unit. They may grow, regress or remain unchanged, as the hormonal environment of the patient changes. Expression of antigen TF in mucin or mucin-type glycoproteins and of galectin-3 seems to contribute to proliferation and transformations events; their expression has been reported in ductal breast cancer and in aggressive tumors. Lectin histochemistry, immunohistochemistry, and immunofluorescence were used to examine the expression and distribution of antigen TF and galectin-3. We used lectins from Arachis hypogaea, Artocarpus integrifolia, and Amaranthus lecuocarpus to evaluate TF expression and a monoclonal antibody to evaluate galectin-3 expression. We used paraffin-embedded blocks from 10 breast tissues diagnosed with fibroadenoma and as control 10 healthy tissue samples. Histochemical and immunofluorescence analysis showed positive expression of galectin-3 in fibroadenoma tissue, mainly in stroma, weak interaction in ducts was observed; whereas, in healthy tissue samples the staining was also weak in ducts. Lectins from A. leucocarpus and A. integrifolia specificaly recognized ducts in healthy breast samples, whereas the lectin from A. hypogaea recognized ducts and stroma. In fibroadenoma tissue, the lectins from A. integrifolia, A. Hypogaea, and A. leucocarpus recognized mainly ducts. Our results suggest that expression of antigen TF and galectin-3 seems to participate in fibroadenoma development.

  8. Expression of antigen tf and galectin-3 in fibroadenoma

    Directory of Open Access Journals (Sweden)

    Gallegos Itandehui Belem

    2012-12-01

    Full Text Available Abstract Background Fibroadenomas are benign human breast tumors, characterized by proliferation of epithelial and stromal components of the terminal ductal unit. They may grow, regress or remain unchanged, as the hormonal environment of the patient changes. Expression of antigen TF in mucin or mucin-type glycoproteins and of galectin-3 seems to contribute to proliferation and transformations events; their expression has been reported in ductal breast cancer and in aggressive tumors. Findings Lectin histochemistry, immunohistochemistry, and immunofluorescence were used to examine the expression and distribution of antigen TF and galectin-3. We used lectins from Arachis hypogaea, Artocarpus integrifolia, and Amaranthus lecuocarpus to evaluate TF expression and a monoclonal antibody to evaluate galectin-3 expression. We used paraffin-embedded blocks from 10 breast tissues diagnosed with fibroadenoma and as control 10 healthy tissue samples. Histochemical and immunofluorescence analysis showed positive expression of galectin-3 in fibroadenoma tissue, mainly in stroma, weak interaction in ducts was observed; whereas, in healthy tissue samples the staining was also weak in ducts. Lectins from A. leucocarpus and A. integrifolia specificaly recognized ducts in healthy breast samples, whereas the lectin from A. hypogaea recognized ducts and stroma. In fibroadenoma tissue, the lectins from A. integrifolia, A. Hypogaea, and A. leucocarpus recognized mainly ducts. Conclusions Our results suggest that expression of antigen TF and galectin-3 seems to participate in fibroadenoma development.

  9. Resilience in IMS

    DEFF Research Database (Denmark)

    Kamyod, Chayapol; Nielsen, Rasmus Hjorth; Prasad, Neeli R.

    2012-01-01

    ) and supporting always on services. Therefore, not only Quality of Service (QoS) but also resilience is required. In this paper, we attempt to evaluate and analyze end-to-end reliability of the IMS system using a model proposed as a combination of Reliability Block Diagram (RBD) and Markov Reward Models (MRMs......Reliability evaluation of systems has been widely researched for improving system resilience especially in designing processes of a complex system. The convergence of different access networks is possible via IP Multimedia Subsystem (IMS) for development toward Next Generation Networks (NGNs......). The resilience of the IMS architecture is studied by applying 1:1 redundancy at different communication scenarios between end users within and across communication domains. The model analysis provides useful reliability characteristics of the system and can be further applied for system design processes....

  10. Delegation und Kooperation im Gesundheitswesen

    OpenAIRE

    Rosenau, Henning

    2010-01-01

    Delegation und Kooperation im Gesundheitswesen. - In: Tıpta işbirliği ve hukuksal sorunlar = Delegation und Kooperation im Gesundheitswesen / ed.: Hakan Hakeri ... - Samsun : Adalet, 2010. - S. 7-18

  11. Cobra-TF simulation of BWR bundle dry out experiments

    Energy Technology Data Exchange (ETDEWEB)

    Frepoli, C.; Ireland, A.; Hochreiter, L.; Ivanov, K. [Penn State Univ., Dept. of Mechanical and Nuclear Engineering, University Park, PA (United States); Velten, R. [Siemens Nuclear Power GmbH, Erlangen (Germany)

    2001-07-01

    The COBRA-TF computer code uses a two-fluid, three-field and three-dimensional formulation to model a two-phase flow field in a specific geometry. The liquid phase is divided in a continuous liquid field and a separate dispersed field, which is used to describe the entrained liquid drops. For each space dimension, the code solves three momentum equations, three mass conservation equations and two energy conservation equations. Entrainment and depositions models are implemented into the code to model the mass transfer between the two liquid fields. This study presents the results obtained with COBRA-TF for the simulation of the Siemens 9-9Q BWR Bundle Dryout experiments. The model includes 20 channels and 34 axial nodes in the heated section. The predicted critical power and dryout location is compared with the measured values. An assessment of the code entrainment and de-entrainment models is presented. (authors)

  12. GENIUS-TF: a test facility for the GENIUS project

    OpenAIRE

    Baudis, L.; Dietz, A.; Heusser, G.; Majorovits, B.; Strecker, H.; Klapdor--Kleingrothaus, H. V.

    2000-01-01

    GENIUS is a proposal for a large scale detector of rare events. As a first step of the experiment, a small test version, the GENIUS test facility, will be build up at the Laboratorio Nazionale del Gran Sasso (LNGS). With about 40 kg of natural Ge detectors operated in liquid nitrogen, GENIUS-TF could exclude (or directly confirm) the DAMA annual modulation signature within about two years of measurement.

  13. Organisationsprobleme im Ökomarketing

    OpenAIRE

    Dienel, Wolfram

    2000-01-01

    Organisationsprobleme im Ökomarketing - eine transaktionskostentheoretische Analyse im Absatzkanal konventioneller Lebensmittelhandel Die im Vergleich zum großen Nachfragepotential zögerliche Entwicklung des Ökomarkts in Deutschland ist auf Organisationsprobleme zurückzuführen. Die Organisationsprobleme behindern insbesondere die großskalige Ökomarkterschließung über die konventionellen Supermarktketten, erschweren aber auch die Effizienzsteigerung im kleiner strukturierten alternativen N...

  14. A restructuring of TF package for MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S. H.; Song, Y. M.; Kim, D. H.

    2002-01-01

    TF package which defines some interpolation and extrapolation condition through user defined table has been restructured in MIDAS computer code. To do this, data transferring methods of current MELCOR code are modified and adopted into TF package. The data structure of the current MELCOR code using FORTRAN77 causes a difficult grasping of the meaning of the variables as well as waste of memory. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type, which lead to an efficient memory treatment and an easy understanding of the code. Restructuring of TF package addressed in this paper does module development and subroutine modification, and treats MELGEN which is making restart file as well as MELCOR which is processing calculation. The validation has been done by comparing the results of the modified code with those from the existing code, and it is confirmed that the results are the same. It hints that the similar approach could be extended to the entire code package. It is expected that code restructuring will accelerate the code domestication thanks to direct understanding of each variable and easy implementation of modified or newly developed models

  15. IMS Application Developer's Handbook Creating and Deploying Innovative IMS Applications

    CERN Document Server

    Noldus, Rogier; Mulligan, Catherine; Fikouras, Ioannis; Ryde, Anders; Stille, Mats

    2011-01-01

    IMS Application Developer Handbook will give a hands-on view of exactly what needs to be done by IMS application developers to write an application and take it "live" on an operator's network. It will offer practical guidance on building innovative applications using the features and capabilities of the IMS network, show how the rapidly changing development environment is impacting on the business models employed in the industry and how existing network solutions can be moved towards IMS. The book will also elaborate on how IMS applies basic VoIP principles and techniques to realise a true mul

  16. Solvation of UCl{sub 6}{sup 2-} anionic complex by MeBu{sub 3}N{sup +}, BuMe{sub 2}Im{sup +} and BuMeIm{sup +} cations

    Energy Technology Data Exchange (ETDEWEB)

    Bosse, Emilie; Den Auwer, Christophe; Berthon, Claude; Guilbaud, Philippe; Moisy, Philippe [CEA Marcoule, DRCP/SCPS, BP 17171, 30207 Bagnols sur Ceze Cedex (France); Grigoriev, Mikhail S. [A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, RAS, Leninskii Prosp. 31, 119991 Moscow (Russian Federation); Nikitenko, Serguei [CNAB, UMR 5084, CNRS - Universite de Bordeaux 1, BP 120 Le Haut Vigneau, 33175 Gradignan Cedex (France); Le Naour, Claire; Cannes, Celine [IPN, UMR 8608, CNRS, Universite Paris-Sud, 91406 Orsay (France)

    2008-07-01

    The complexes [MeBu{sub 3}N]{sub 2}[UCl{sub 6}] and [BuMe{sub 2}Im]{sub 2}[UCl{sub 6}] were characterized in the solid state and in solution of [MeBu{sub 3}N][Tf{sub 2}N], [BuMe{sub 2}Im][Tf{sub 2}N] and [BuMeIm][Tf{sub 2}N] room temperature ionic liquids using single-crystal XRD, EXAFS, electrochemistry, UV-visible absorption spectroscopy and NMR. In the solid and in solution, the existence of hydrogen bonding between the anionic UCl{sub 6}{sup 2-} complex and the ionic liquid cations were revealed by these techniques. The MeBu{sub 3}N{sup +} cation interacts with UCl{sub 6}{sup 2-} via the protons on the alpha carbon atoms of nitrogen. The protons of the imidazolium ring account for the interaction between the BuMe{sub 2}Im+ cation and the UCl{sub 6}{sup 2-} anion. For the BuMeIm{sup +} cation the major interaction was confirmed between the most acidic proton on C(2) and UCl{sub 6}{sup 2-}. The experimental results also show that the intensity of the interaction between the UCl{sub 6}{sup 2-} anion and the cation varies with the ionic liquid cation in the following order: MeBu{sub 3}N{sup +} {approx} BuMe{sub 2}Im{sup +} << BuMeIm{sup +}. (authors)

  17. Sexting im Schulumfeld

    Directory of Open Access Journals (Sweden)

    Barbara Buchegger

    2015-03-01

    Full Text Available Wir wollten es einfach wissen. Wie steht es nun mit diesem "Sexting" – also der Übermittlung von Nacktaufnahmen, die Jugendliche untereinander teilen? Stimmt unser Eindruck aus den Workshops in Schulen, dass es bereits ein "übliches Verhalten" der Jugendlichen geworden ist? Saferinternet.at hat im November/Dezember 2014 eine Studie durch das Institut für Jugendkulturforschung rund um das Thema "Sexting" in Auftrag gegeben.

  18. Operation of SST-1 TF power supply during SST-1 campaigns

    International Nuclear Information System (INIS)

    Sharma, Dinesh Kumar; Vora, Murtuza M.; Ojha, Amit; Singh, Akhilesh Kumar; Bhavsar, Chirag

    2015-01-01

    Highlights: • SST-1 TF power supply is 12 pulse SCR converter circuit. • TF power supply protection, measurement and control scheme are explained. • Quench, emergency and normal shot process is explained and results of SST-1 campaigns are shown. • Dynamic control of TF current. • The paper shows the results of last ten SST-1 campaigns. - Abstract: SST-1 TF power supply provides the direct current for the required magnetic field of TF coil. TF power supply includes transformer, 12-pulse converter, bus bar, water-cooled cable, protection and measuring equipments, and isolator, VME DAC system and GUI software. TF power supply is operated through GUI software built in TCL/Tk. VME DAC system monitors the parameters, provides On/Off commands, voltage and current references and initiates predefined reference to emergency shutdown. The emergency shutdown is hardwired to TF power supply from central control. During quench power supply converter opens DCCB and dump resistor is connected in the circuit and VME DAC system acquires bus bar voltage, dump voltage and dump current. Operation of TF power supply also requires monitoring of SCR and transformer temperature and water flow rate of water-cooled cable during high current long pulse shot. Before start up of TF power supply a quench simulation is performed to check the readiness of protection. This paper describes pre startup operation, normal shot operation, emergency and quench process, dynamic control and complete shutdown operation of TF power supply.

  19. Operation of SST-1 TF power supply during SST-1 campaigns

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, Dinesh Kumar, E-mail: dinesh@ipr.res.in; Vora, Murtuza M.; Ojha, Amit; Singh, Akhilesh Kumar; Bhavsar, Chirag

    2015-10-15

    Highlights: • SST-1 TF power supply is 12 pulse SCR converter circuit. • TF power supply protection, measurement and control scheme are explained. • Quench, emergency and normal shot process is explained and results of SST-1 campaigns are shown. • Dynamic control of TF current. • The paper shows the results of last ten SST-1 campaigns. - Abstract: SST-1 TF power supply provides the direct current for the required magnetic field of TF coil. TF power supply includes transformer, 12-pulse converter, bus bar, water-cooled cable, protection and measuring equipments, and isolator, VME DAC system and GUI software. TF power supply is operated through GUI software built in TCL/Tk. VME DAC system monitors the parameters, provides On/Off commands, voltage and current references and initiates predefined reference to emergency shutdown. The emergency shutdown is hardwired to TF power supply from central control. During quench power supply converter opens DCCB and dump resistor is connected in the circuit and VME DAC system acquires bus bar voltage, dump voltage and dump current. Operation of TF power supply also requires monitoring of SCR and transformer temperature and water flow rate of water-cooled cable during high current long pulse shot. Before start up of TF power supply a quench simulation is performed to check the readiness of protection. This paper describes pre startup operation, normal shot operation, emergency and quench process, dynamic control and complete shutdown operation of TF power supply.

  20. Palmitoylation of Sindbis Virus TF Protein Regulates Its Plasma Membrane Localization and Subsequent Incorporation into Virions.

    Science.gov (United States)

    Ramsey, Jolene; Renzi, Emily C; Arnold, Randy J; Trinidad, Jonathan C; Mukhopadhyay, Suchetana

    2017-02-01

    Palmitoylation is a reversible, posttranslational modification that helps target proteins to cellular membranes. The alphavirus small membrane proteins 6K and TF have been reported to be palmitoylated and to positively regulate budding. 6K and TF are isoforms that are identical in their N termini but unique in their C termini due to a -1 ribosomal frameshift during translation. In this study, we used cysteine (Cys) mutants to test differential palmitoylation of the Sindbis virus 6K and TF proteins. We modularly mutated the five Cys residues in the identical N termini of 6K and TF, the four additional Cys residues in TF's unique C terminus, or all nine Cys residues in TF. Using these mutants, we determined that TF palmitoylation occurs primarily in the N terminus. In contrast, 6K is not palmitoylated, even on these shared residues. In the C-terminal Cys mutant, TF protein levels increase both in the cell and in the released virion compared to the wild type. In viruses with the N-terminal Cys residues mutated, TF is much less efficiently localized to the plasma membrane, and it is not incorporated into the virion. The three Cys mutants have minor defects in cell culture growth but a high incidence of abnormal particle morphologies compared to the wild-type virus as determined by transmission electron microscopy. We propose a model where the C terminus of TF modulates the palmitoylation of TF at the N terminus, and palmitoylated TF is preferentially trafficked to the plasma membrane for virus budding. Alphaviruses are a reemerging viral cause of arthritogenic disease. Recently, the small 6K and TF proteins of alphaviruses were shown to contribute to virulence in vivo Nevertheless, a clear understanding of the molecular mechanisms by which either protein acts to promote virus infection is missing. The TF protein is a component of budded virions, and optimal levels of TF correlate positively with wild-type-like particle morphology. In this study, we show that the

  1. GENIUS-TF: a test facility for the GENIUS project

    International Nuclear Information System (INIS)

    Klapdor-Kleingrothaus, H.V.; Baudis, L.; Dietz, A.; Heusser, G.; Krivosheina, I.; Majorovits, B.; Strecker, H.

    2002-01-01

    GENIUS is a proposal for a large scale detector of rare events. As a first step of the experiment, a small test version, the Genius Test-Facility will be built at the Laboratori Nazionali del Gran Sasso. With about 40 kg of natural Ge detectors operated in liquid nitrogen, GENIUS-TF could exclude (or directly confirm) the DAMA annual modulation seasonal modulation signature within about 2 yr of measurement using both, signal and signature of the claimed WIMP Dark Matter. The construction of the experiment has already been started, and four 2.5 kg germanium detectors with an extreme low threshold of 500 eV have been produced

  2. Clustering of malaria treatment failure (TF) in Daraweesh: hints for host genetic susceptibility to TF with emphasis on immune-modulating SNPs

    DEFF Research Database (Denmark)

    Giha, Hayder A; ElGhazali, Gehad; Nasr, Amre

    2010-01-01

    In malaria, drug resistance and treatment failure (TF) are not synonymous, although are escalating together. Over 9 years of surveillances for malaria morbidity and TF in Daraweesh village in eastern Sudan (1991-2004), 136 donors (15-78 years) from 43 households, treated for 278 malaria episodes ...

  3. Investigation of sensors and instrument components in boiling water reactors. Results from Oskarshamn 2, Barsebaeck 2 in Sweden and Kernkraftwerk Muehleberg in Switzerland

    International Nuclear Information System (INIS)

    Bergdahl, B.G.

    1998-05-01

    The reactor monitoring instruments are important for the operation and safety of the plants. Static properties of the instruments are controlled annually, but the dynamic properties are rarely, if ever, examined. This study is the result of a project initiated by the Swedish Nuclear Power Inspectorate. The examinations are based on signal analysis and simultaneous measurement of multiple signals. Results from Oskarshamn 2 (O2), Barsebaeck 2 (B2) and Kernkraftwerk Muehleberg (KKM) are discussed in this report. The presentation is focused on reactor pressure and reactor level signals. the analysis of O2 revealed that the dynamics for 3 out of 14 sensors was 'filtered', meaning that a rapid level displacement is registered with delay. Inspection showed that a 1 sec filter was installed instead of 1.2 sec. The study also showed that old pressure-sensors in use both at O2 and B2 could not cope with high frequencies, and that some level-sensors were disturbed by mechanical oscillations at Bw. At KKM, a 2 Hz resonance was observed with 12 pressure and level sensors. The oscillation was created by an old pressure sensor and influenced the other sensors through the common impulse network

  4. Short initial length quench on CICC of ITER TF coils

    International Nuclear Information System (INIS)

    Nicollet, S.; Ciazynski, D.; Duchateau, J.-L.; Lacroix, B.; Bessette, D.; Rodriguez-Mateos, F.; Coatanea-Gouachet, M.; Gauthier, F.

    2014-01-01

    Previous quench studies performed for the International Thermonuclear Experimental Reactor (ITER) Toroidal Field (TF) Coils have led to identify two extreme families of quench: first 'severe' quenches over long initial lengths in high magnetic field, and second smooth quenches over short initial lengths in low field region. Detailed analyses and results on smooth quench propagation and detectability on one TF Cable In Conduit Conductor (CICC) with a lower propagation velocity are presented here. The influence of the initial quench energy is shown and results of computations with either a Fast Discharge (FD) of the magnet or without (failure of the voltage quench detection system) are reported. The influence of the central spiral of the conductor on the propagation velocity is also detailed. In the cases of a regularly triggered FD, the hot spot temperature criterion of 150 K (with helium and jacket) is fulfilled for an initial quench length of 1 m, whereas this criterion is exceed (Tmax ≈ 200 K) for an extremely short length of 5 cm. These analyses were carried out using both the Supermagnet(trade mark, serif) and Venecia codes and the comparisons of the results are also discussed

  5. Identifying TF-MiRNA Regulatory Relationships Using Multiple Features.

    Directory of Open Access Journals (Sweden)

    Mingyu Shao

    Full Text Available MicroRNAs are known to play important roles in the transcriptional and post-transcriptional regulation of gene expression. While intensive research has been conducted to identify miRNAs and their target genes in various genomes, there is only limited knowledge about how microRNAs are regulated. In this study, we construct a pipeline that can infer the regulatory relationships between transcription factors and microRNAs from ChIP-Seq data with high confidence. In particular, after identifying candidate peaks from ChIP-Seq data, we formulate the inference as a PU learning (learning from only positive and unlabeled examples problem. Multiple features including the statistical significance of the peaks, the location of the peaks, the transcription factor binding site motifs, and the evolutionary conservation are derived from peaks for training and prediction. To further improve the accuracy of our inference, we also apply a mean reciprocal rank (MRR-based method to the candidate peaks. We apply our pipeline to infer TF-miRNA regulatory relationships in mouse embryonic stem cells. The experimental results show that our approach provides very specific findings of TF-miRNA regulatory relationships.

  6. Short initial length quench on CICC of ITER TF coils

    Energy Technology Data Exchange (ETDEWEB)

    Nicollet, S.; Ciazynski, D.; Duchateau, J.-L.; Lacroix, B. [CEA, IRFM, F-13108 Saint-Paul-lez-Durance (France); Bessette, D.; Rodriguez-Mateos, F. [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Coatanea-Gouachet, M. [ELC Engineering, 350 chemin du Verladet, F-13290 Les Milles (France); Gauthier, F. [Soditech Ingenierie, 4 bis allée des Gabians, ZI La Frayère, 06150 Cannes (France)

    2014-01-29

    Previous quench studies performed for the International Thermonuclear Experimental Reactor (ITER) Toroidal Field (TF) Coils have led to identify two extreme families of quench: first 'severe' quenches over long initial lengths in high magnetic field, and second smooth quenches over short initial lengths in low field region. Detailed analyses and results on smooth quench propagation and detectability on one TF Cable In Conduit Conductor (CICC) with a lower propagation velocity are presented here. The influence of the initial quench energy is shown and results of computations with either a Fast Discharge (FD) of the magnet or without (failure of the voltage quench detection system) are reported. The influence of the central spiral of the conductor on the propagation velocity is also detailed. In the cases of a regularly triggered FD, the hot spot temperature criterion of 150 K (with helium and jacket) is fulfilled for an initial quench length of 1 m, whereas this criterion is exceed (Tmax ≈ 200 K) for an extremely short length of 5 cm. These analyses were carried out using both the Supermagnet(trade mark, serif) and Venecia codes and the comparisons of the results are also discussed.

  7. Magnetic field shielding effect for CFETR TF coil-case

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Weiwei; Liu, Xufeng, E-mail: Lxf@ipp.ac.cn; Du, Shuangsong; Zheng, Jinxing

    2017-05-15

    Highlights: • The eddy current of CFETR vacuum vessel can be calculated by using a series of ideal current loops. • The shielding effect with different eddy current is studied by decomposing the exciting magnetic field as two orthogonal components. • The shielding effect can be determined from the rate of eddy current magnetic field to the external magnetic field. - Abstract: The operation of superconducting magnet for fusion device is under the complex magnetic field condition, which affect the stabilization of superconductor. The coil-case of TF coil can shield the magnetic field to some extent. The shielding effect is related to the eddy current of coil-case. The shielding effect with different eddy current is studied by decomposing the exciting magnetic field as two orthogonal components, respectively. The results indicate that the shielding effect of CFETR TF coil-case has obvious different with the different directional magnetic field, and it’s larger for tangential magnetic compared with that for normal field.

  8. Thermo hydraulic and quench propagation characteristics of SST-1 TF coil

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, A.N., E-mail: ansharma@ipr.res.in [Institute for Plasma Research, Gandhinagar (India); Pradhan, S. [Institute for Plasma Research, Gandhinagar (India); Duchateau, J.L. [CEA Cadarache, 13108 St Paul lez Durance Cedex (France); Khristi, Y.; Prasad, U.; Doshi, K.; Varmora, P.; Patel, D.; Tanna, V.L. [Institute for Plasma Research, Gandhinagar (India)

    2014-02-15

    Highlights: • Details of SST-1 TF coils, CICC. • Details of SST-1 TF coil cold test. • Quench analysis of TF magnet. • Flow changes following quench. • Predictive analysis of assembled magnet system. - Abstract: SST-1 toroidal field (TF) magnet system is comprising of sixteen superconducting modified ‘D’ shaped TF coils. During single coil test campaigns spanning from June 10, 2010 till January 24, 2011; the electromagnetic, thermal hydraulic and mechanical performances of each TF magnet have been qualified at its respective nominal operating current of 10,000 A in either two-phase or supercritical helium cooling conditions. During the current charging experiments, few quenches have initiated either as a consequence of irrecoverable normal zones or being induced in some of the TF magnets. Quench evolution in the TF coils have been analyzed in detail in order to understand the thermal hydraulic and quench propagation characteristics of the SST-1 TF magnets. The same were also simulated using 1D code Gandalf. This paper elaborates the details of the analyses and the quench simulation results. A predictive quench propagation analysis of 16 assembled TF magnets system has also been reported in this paper.

  9. IMS applications analysis

    Energy Technology Data Exchange (ETDEWEB)

    RODACY,PHILIP J.; REBER,STEPHEN D.; SIMONSON,ROBERT J.; HANCE,BRADLEY G.

    2000-03-01

    This report examines the market potential of a miniature, hand-held Ion Mobility Spectrometer. Military and civilian markets are discussed, as well as applications in a variety of diverse fields. The strengths and weaknesses of competing technologies are discussed. An extensive Ion Mobility Spectrometry (IMS) bibliography is included. The conclusions drawn from this study are: (1) There are a number of competing technologies that are capable of detecting explosives, drugs, biological, or chemical agents. The IMS system currently represents the best available compromise regarding sensitivity, specificity, and portability. (2) The military market is not as large as the commercial market, but the military services are more likely to invest R and D funds in the system. (3) Military applications should be addressed before commercial applications are addressed. (4) There is potentially a large commercial market for rugged, hand-held Ion Mobility Spectrometer systems. Commercial users typically do not invest R and D funds in this type of equipment rather, they wait for off-the-shelf availability.

  10. The emerging role of neutrophils in thrombosis – The journey of TF through NETs

    Directory of Open Access Journals (Sweden)

    Konstantinos eKambas

    2012-12-01

    Full Text Available The production of TF by neutrophils and their contribution in thrombosis was until recently a matter of scientific debate. Experimental data suggested the de novo TF production by neutrophils under inflammatory stimuli, while others proposed that these cells acquired microparticle-derived TF. Recent experimental evidence revealed the critical role of neutrophils in thrombotic events. Neutrophil derived TF has been implicated in this process in several human and animal models. Additionally, neutrophil extracellular trap (NET release has emerged as a major contributor in neutrophil-driven thrombogenicity in disease models including sepsis, deep venous thrombosis and malignancy. It is suggested that NETs provide the scaffold for fibrin deposition and platelet entrapment and subsequent activation. The recently reported autophagy-dependent extracellular delivery of TF in NETs further supports the involvement of neutrophils in thrombosis. Herein, we seek to review novel data regarding the role of neutrophils in thrombosis, emphasizing the implication of TF and NETs.

  11. TIBER-II TF [toroidal-field] winding pack design

    International Nuclear Information System (INIS)

    Kerns, J.A.; Miller, J.R.; Slack, D.S.; Summers, L.T.

    1987-01-01

    The superconducting, toroidal-field (TF) coils in the Tokamak Ignition/Burn Engineering Reactor (TIBER II) are designed with cable-in-conduit conductor (CICC) using Nb 3 Sn composite strands. To design the CICC winding pack, we used an optimization technique that maximizes the conductor stability without violating the constraints imposed by the structure, electrical insulation, quench protection, and fabrication technique. Detailed helium-properties codes calculate the heat removal along a flow path, and detailed field calculations determine the temperature, current, and stability margins. The conductor sheath is designed as distributed structure to partially support the combined in-plane and out-of-plane loads generated within the winding pack. Pancakes of the coil are wound, reacted, and insulated before being potted in the case. This design is aggressive but fully consistent with good engineering practice. 5 refs., 4 figs., 2 tabs

  12. Study for Manufacturing of ITER TF Coil Radial Plates

    International Nuclear Information System (INIS)

    Fietz, W.H.; Muetzel, W.

    2006-01-01

    During the previous design phase of ITER the ITER Toroidal Field Model Coil (TFMC) has been built to verify the TF coil concept of ITER and to proof the feasibility of an industrial fabrication of such a coil. In April 2004, Forschungszentrum and BNG, started a Manufacturing Study for the full scale Radial Plates (RP) of the TF Coils in the frame of an EFDA task. The main part of the Study was to develop feasible concepts of the technology for the manufacturing of the Full Scale Radial Plates starting with the raw material until final testing. The Feasibility Study has covered all manufacturing steps that are necessary for production of the RP. It has included as well a basic layout for the manufacturing process. During the work several proposals for the single manufacturing work steps have been developed. After that an evaluation of the found proposals has taken place. The most feasible proposals have been combined to manufacturing concepts. Finally two main Concepts were elaborated and evaluated: Concept 1 includes the premachining of segments with grooves, the welding of the segments and the final machining of the RP. Concept 2 includes the welding of not machined small segments to the D-shape of the RP and the following machining of the surface and grooves. Both Concepts will be described in detail with a comparison of tooling and manufacturing details, achievement of technological requirements as well as with the requirements coming from the overall time schedule. Based on the results of the assessment of the different concepts and manufacturing techniques Concept 1 shows some advantages compared to Concept 2. These will be described in the paper. In addition a proposal about additional R(and)D in front of the later manufacturing will be made. (author)

  13. Development of manufacturing technology for ITER TF Coil Structure

    Energy Technology Data Exchange (ETDEWEB)

    Sakurai, Takeru, E-mail: sakurai.takeru@jaea.go.jp; Iguchi, Masahide; Nakahira, Masataka; Inagaki, Takashi; Matsui, Kunihiro; Koizumi, Norikiyo

    2016-11-01

    Highlights: • Heavy thick welding (Max. 287 mm) was performed by balance welding. • Figured out Attachment welding deformation including heavy thick welding. • The deformation of Segments welding was suppressed to 1/3 of previous method. • Based on this study, JAEA started actual ITER TF coil structure manufacturing. - Abstract: Japan Atomic Energy Agency (JAEA) performed a trial of A1 Segment manufacturing of Toroidal Field (TF) coil structure, which is a piece with a radius of curvature 3 m with square channel for coil. Even though both-side welding (balance welding) was preferred to one-side welding considering the welding deformation, it could not be applied to the previous trial due to the difficulty of overhead or horizontal welding by machine. Hence, one-side welding with strong restriction jig was applied in the previous trials. In the latest trial, JAEA adopted a manual balance welding with a development of manufacturing technology. As the result of A1 Segment Mainbody welding trial, welding deformation of the Outer Plate and the Side Plate could have been controlled closer to the target value. JAEA also tried Attachments welding, in which Pre-Compression Flange (PCF) and Extension are welded to A1 Segment Mainbody, and a Segments welding trial, which is a weld between A1 Segment and a part of A2 Segment. A2 Segment is a 3 m straight part with square channel for coil. The inclination of A1 Segment and A2 Segment due to the welding was 2.7 mm. By applying balance welding, the deformation by Segments welding was suppressed to about 1/3 of the one-side welding. The views and opinions expressed herein do not necessarily reflect those of the ITER Organization.

  14. Structural analysis of TFTR TF coils and support structure for 6 Tesla operation

    International Nuclear Information System (INIS)

    Zatz, I.J.; Cargulia, G.; Lontai, L.

    1995-01-01

    The Tokamak Fusion Test Reactor (TFTR), which has been on line since December 1982, has successfully operated at its design Toroidal Field (TF) of 5.2 Tesla. Analysis of test data has indicated that the measured peak D-D neutron power in supershots may be scaled to the fourth power of TF field. Increasing the TF field to 6 Tesla provides the opportunity to explore the possibility of improving the D-T fusion yield, with the use of tritium. This increase in TF field from 5.2 to 6.0 Tesla increases the centering force by 33% and the out-of-plane force by 15% over previous peak operating levels. To examine the impact of the increase in loads on the TF coil, case and supporting structure, finite element analyses (FEA) were performed with and without the presence of loose bolts in the TF case. Note that the loose bolts comprise a fraction of the total number of bolts fastening the TF case sidewalls to the inner and outer rings of the case. Extensive analysis was performed using the FEA results in conjunction with supplementary calculations. Results are presented for the TF case, bolts, copper conductors, insulation, and supporting structure which indicate that the TF coils can successfully operate at 6 Tesla for a reasonable number of pulses

  15. Quench characterization and thermo hydraulic analysis of SST-1 TF magnet busbar

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, A.N., E-mail: ansharma@ipr.res.in [Institute for Plasma Research, Gandhinagar (India); Pradhan, S. [Institute for Plasma Research, Gandhinagar (India); Duchateau, J.L. [CEA Cadarache, 13108 St Paul lez Durance Cedex (France); Khristi, Y.; Prasad, U.; Doshi, K.; Varmora, P.; Tanna, V.L.; Patel, D.; Panchal, A. [Institute for Plasma Research, Gandhinagar (India)

    2015-01-15

    Highlights: • Details of SST-1 TF busbar quench detection. • Simulation of slow propagating normal zone. • Thermo hydraulic analyses of TF busbar in current feeder system. - Abstract: Toroidal field (TF) magnet system of steady-state superconducting tokamak-1 (SST-1) has 16 superconducting coils. TF coils are cooled with forced flow supercritical helium at 0.4 MPa, at 4.5 K and operate at nominal current of 10,000 A. Prior to TF magnet system assembly in SST-1 tokamak, each TF coil was tested individually in a test cryostat. During these tests, TF coil was connected to a pair of conventional helium vapor cooled current leads. The connecting busbar was made from the same base cable-in-conduit-conductor (CICC) of SST-1 superconducting magnet system. Quenches experimentally observed in the busbar sections of the single coil test setups have been analyzed in this paper. A steady state thermo hydraulic analysis of TF magnet busbar in actual SST-1 tokamak assembly has been done. The experimental observations of quench and results of relevant thermo hydraulic analyses have been used to predict the safe operation regime of TF magnet system busbar during actual SST-1 tokamak operational scenarios.

  16. A new sample treatment for asialo-Tf determination with capillary electrophoresis: an added value to the analysis of CDT.

    Science.gov (United States)

    Porpiglia, Nadia Maria; De Palo, Elio Franco; Savchuk, Sergey Alexandrovich; Appolonova, Svetlana Alexandrovna; Bortolotti, Federica; Tagliaro, Franco

    2018-05-10

    The non-glycosylated glycoform of transferrin (Tf), known as asialo-Tf, was not selected (in favor of disialo-Tf) as the measurand for the standardization of carbohydrate deficient transferrin (CDT) determination because of a lower diagnostic sensitivity provided with the currently available analytical procedures for sera. However, asialo-Tf could provide an additional value to disialo-Tf in the CDT analysis employed in forensic toxicology contexts. The present work aimed at developing an easy sample preparation based on PEG precipitation in order to improve the detectability of asialo-Tf in capillary electrophoresis (CE). Equal volumes (35 μL) of serum and of 30% PEG-8000 were mixed and briefly vortexed. After centrifugation, the supernatant was iron saturated with a ferric solution (1:1, v/v). The mixture was analyzed in CE for asialo-Tf and disialo-Tf determination. PEG-8000 precipitation allowed the improvement of the baseline in the electropherograms in terms of interferences reduction particularly in the asialo-Tf migration region. The detection of asialo-Tf was possible in 89% of samples with disialo-Tf above the cut-off limit, whereas only 16% of them showed asialo-Tf by employing the traditional sample preteatment. Asialo-Tf represents an additional value to disialo-Tf as a biomarker of alcohol abuse in forensic toxicology. Copyright © 2018. Published by Elsevier B.V.

  17. Special remote tooling developed and utilized to tighten TFTR TF coil casing bolts

    International Nuclear Information System (INIS)

    Burgess, T.W.; Walton, G.R.; Meighan, T.G.; Paul, B.L.

    1993-01-01

    Special tooling has been developed and used to tighten toroidal field (TF) coil casing bolts that have loosened from years of Tokamak Fusion Test Reactor (TFTR) operation. Due to their location, many of the TF casing bolts cannot be directly accessed or viewed; their condition was first discovered during unrelated inspections in 1988. Engineering solutions were, sought until 1992, when a remotely operated wrench concept was successfully demonstrated on a TF coil mockup. The concept was developed into several working tools that have successfully been applied to tighten several thousand TF casing bolts during recent scheduled outages. This effort has improved the integrity and reliability of the TF coil system in preparing for the final experimental phase of the TFTR. This paper discusses the design and application of this tooling

  18. JT-60SA TF magnet industrial manufacturing preparation and qualifications

    International Nuclear Information System (INIS)

    Decool, P.; Cloez, H.; Gros, G.; Marechal, J.L.; Torre, A.; Verger, J.M.; Nusbaum, M.; Billotte, G.; Crepel, B.; Bourquard, A.; Davis, S.; Phillips, G.

    2014-01-01

    The general design of the JT-60SA toroidal field system was defined in agreement with all the participants in the project (CEA, ENEA, F4E), the detailed design was issued by the Voluntary Contributors. For the French part including the procurement of 9 of the 18 TF winding packs and their integration in the casings, an industrial contract was signed mid-2011 with Alstom (France). After agreement on manufacturing drawings and QA documentation, the manufacturing process was defined giving the guidelines for the workshop organization and the definition of the required tooling. The critical manufacturing points were identified in the process and, regarding technical requirements, have led to the definition of a set of qualification mockups. They are related to helium inlets, conductor winding and insulation, local conductor bending, electrical joint and terminal areas for the winding pack (WP), as well as winding embedding, case welding, and impregnations for WP integration in the casing. The fabrication processes have been improved and shall be qualified thanks to the manufacture and testing of 12 corresponding mockups. The successful achievement of several key mock-ups gives confidence in the feasibility of the manufacture, and their completion will give the green light to the industrial coils manufacture. (authors)

  19. Qualification tests for ITER TF conductors in SULTAN

    International Nuclear Information System (INIS)

    Bruzzone, P.; Stepanov, B.; Wesche, R.

    2009-01-01

    From February 2007 to May 2008, 18 short length conductor sections have been tested in SULTAN for design verification and manufacturer qualification of the ITER Toroidal Field (TF) conductor. The test program is focussed on the current sharing temperature, T cs , at the nominal operating conditions, 68 kA current and 11.15 T effective field, which can be fully reproduced in the SULTAN test facility. A broad range of results was observed, with over 2 K difference among the T cs of the conductors. In average, the results are poorer compared to the potential performance estimated from the strand scaling law. The key parameters to mitigate the degradation are not yet clearly identified. The experimental challenges to test conductors with performance degradation are highlighted, including enhanced instrumentation sets, the application of gas flow calorimetry to sense the current sharing power and the post-processing of voltage data to cancel the transverse potential across the cable. The updated schedule of the tests in SULTAN is presented with the short-term action plan for conductor test.

  20. Proposals for cold testing of the ITER TF coils

    International Nuclear Information System (INIS)

    Libeyre, P.; Ciazynski, D.; Dolgetta, N.; Duchateau, J.L.; Lyraud, C.; Kircher, F.; Schild, T.; Fietz, W.H.; Zahn, G.

    2005-01-01

    The ITER Toroidal Field (TF) magnet system will be made of 18 coils using Nb 3 Sn as superconducting material. These coils will operate at a maximum field of 11.8 T for a nominal current of 68 kA carried by a dual channel cable-in-conduit conductor cooled by a forced flow of supercritical helium at 4.5 K. In each coil, seven 760 m conductor lengths wound in double pancakes will be connected to each other by low resistance joints. As a final step of the reception tests, it is proposed to perform cold tests of these coils at liquid helium temperature after completion of their manufacture. The testing shall include high voltage tests to check the quality of the insulation, leak tests and pressure drop measurements of the hydraulic circuits as well as measurement of the joint resistances. Testing the coils up to nominal current is a discussed option, addressing on one hand measurement of the electrical performances in self field and on the other hand the mechanical behaviour of the coils. To perform these tests, a dedicated test facility has to be built, allowing possible simultaneous testing of two coils, assembled together in a twin coil configuration, similarly to their assembly in the torus. (authors)

  1. Proposals for cold testing of the ITER TF coils

    Energy Technology Data Exchange (ETDEWEB)

    Libeyre, P.; Ciazynski, D.; Dolgetta, N.; Duchateau, J.L.; Lyraud, C. [Association Euratom/CEA Cadarache, Dept. de Recherches sur la Fusion Controlee (DRFC), 13 - Saint-Paul-lez-Durance (France); Kircher, F.; Schild, T. [CEA Saclay, Dept. d' Astrophysique, de Physique des Particules, de Physique Nucleaire et de l' Instrumentation Associee, 91- Gif sur Yvette (France); Fietz, W.H.; Zahn, G. [Association Euratom-Forschungszentrum Karlsruhe, Karlsruhe (Germany)

    2005-07-01

    The ITER Toroidal Field (TF) magnet system will be made of 18 coils using Nb{sub 3}Sn as superconducting material. These coils will operate at a maximum field of 11.8 T for a nominal current of 68 kA carried by a dual channel cable-in-conduit conductor cooled by a forced flow of supercritical helium at 4.5 K. In each coil, seven 760 m conductor lengths wound in double pancakes will be connected to each other by low resistance joints. As a final step of the reception tests, it is proposed to perform cold tests of these coils at liquid helium temperature after completion of their manufacture. The testing shall include high voltage tests to check the quality of the insulation, leak tests and pressure drop measurements of the hydraulic circuits as well as measurement of the joint resistances. Testing the coils up to nominal current is a discussed option, addressing on one hand measurement of the electrical performances in self field and on the other hand the mechanical behaviour of the coils. To perform these tests, a dedicated test facility has to be built, allowing possible simultaneous testing of two coils, assembled together in a twin coil configuration, similarly to their assembly in the torus. (authors)

  2. Jung und Alt im Dialog

    Directory of Open Access Journals (Sweden)

    Caroline Baetge

    2012-04-01

    Full Text Available Rezension zu: Kupser, Thomas, und Ida Pöttinger, Hrsg. 2011. Mediale Brücken: Generationen im Dialog durch aktive Medienarbeit. Gesellschaft - Altern - Medien 3. München: kopaed.

  3. Gesundheit und Pflege im Alter

    OpenAIRE

    Pfaff, Martin

    1989-01-01

    Gesundheit und Pflege im Alter : d. Gesundheitsreformgesetz (GRG) ; Möglichkeiten, Grenzen u. weitere Vorschläge / Martin Pfaff ; Klaus Deimer. - In: Expertengespräch "Pflege in der Familie". - Augsburg, 1989. - Getr. Zählung

  4. Resilience of the IMS system

    DEFF Research Database (Denmark)

    Kamyod, Chayapol; Nielsen, Rasmus Hjorth; Prasad, Neeli R.

    2014-01-01

    The paper focuses on end-to-end resilience analysis of the IMS based network through the principal resilience parameters by using OPNET. The resilience behaviours of communication across multiple IMS domains are investigated at different communication scenarios and compared with previous state......-of-the-art. Moreover, the resilience effects when adding a redundancy of the S-CSCF unit are examined. The results disclose interesting resilience behaviours for long distance communications....

  5. Philips Gemini TF64 PET/CT Acceptance Testing

    International Nuclear Information System (INIS)

    González Gonzalez, Joaquín J.; Calderón Marin, Carlos F.; Varela Corona, Consuelo; Machado Tejeda, Adalberto; González Correa, Héctor J.

    2016-01-01

    The Philips Gemini TF64 is the first PET/CT scanner installed in Cuba at the Institute of Oncology and Radiobiology in 2014. It is a third generation fully tridimensional whole body PET scanner with time-of-flight (TOF) technology combined with a 64-slice Brilliance CT scanner. The CT detector module contains 672x64 solid state detector, incorporating GOS scintillators, optical diodes and electronic signal channels arranged in 64 side by side arcs, with 672 detectors in each arc. There are sixteen 0.75 mm individual detector elements around the center and four 1.5 mm elements at each end, resulting in a 24 mm total detection length. The PET detector consists of 28 pixelar modules of a 23x44 array of 4x4x22 mm3 of LYSO crystals arranged in an Anger-logic detector design. The hardware coincidence-timing window for this scanner is set at 4 ns and delayed coincidence window technique is used to estimate the random coincidences in collected data. In this study the performance characteristics of PET/CT scanner were measured as part of the program tests of acceptance for clinical use.Methodology. The performance characteristics of CT scanner were evaluated by manufacturer protocol using Philips system performance phantom. Some additional geometrical tests were performed by the user. The intrinsic measurements of energy resolution as well as timing resolution, which define the TOF performance of PET scanner, were performed following the recommendations of manufacturer using 18 F. Spatial resolution, sensitivity, scatter fraction, counting rate performance, image quality and accuracy were measured according to the NEMA NU-2 2007 procedures. Additionally, to characterize the effect of TOF reconstruction on lesion contrast and noise, the standard NEMA torso phantom was reconstructed with and without TOF capability. The accuracy of PET/CT image registration was tested according to the manufacturer protocol using an image alignment calibration holder with 6 point sources of 22

  6. FVIIa-sTF and Thrombin Inhibitory Activities of Compounds Isolated from Microcystis aeruginosa K-139

    Directory of Open Access Journals (Sweden)

    Andrea Roxanne J. Anas

    2017-08-01

    Full Text Available The rise of bleeding and bleeding complications caused by oral anticoagulant use are serious problems nowadays. Strategies that block the initiation step in blood coagulation involving activated factor VII-tissue factor (fVIIa-TF have been considered. This study explores toxic Microcystis aeruginosa K-139, from Lake Kasumigaura, Ibaraki, Japan, as a promising cyanobacterium for isolation of fVIIa-sTF inhibitors. M. aeruginosa K-139 underwent reversed-phase solid-phase extraction (ODS-SPE from 20% MeOH to MeOH elution with 40%-MeOH increments, which afforded aeruginosin K-139 in the 60% MeOH fraction; micropeptin K-139 and microviridin B in the MeOH fraction. Aeruginosin K-139 displayed an fVIIa-sTF inhibitory activity of ~166 µM, within a 95% confidence interval. Micropeptin K-139 inhibited fVIIa-sTF with EC50 10.62 µM, which was more efficient than thrombin inhibition of EC50 26.94 µM. The thrombin/fVIIa-sTF ratio of 2.54 in micropeptin K-139 is higher than those in 4-amidinophenylmethane sulfonyl fluoride (APMSF and leupeptin, when used as positive controls. This study proves that M. aeruginosa K-139 is a new source of fVIIa-sTF inhibitors. It also opens a new avenue for micropeptin K-139 and related depsipeptides as fVIIa-sTF inhibitors.

  7. Tolerance Evaluation of Poloidal Shear Keys for ITER TF Coil

    International Nuclear Information System (INIS)

    Fu Youkun; Neil, M.; Cees Jong

    2006-01-01

    There are 18 ITER Toroidal Field (TF) Coils. Unlike the other ITER coils, these coils are structurally linked. These links consist of friction between the coil legs in the central vault formed by the inner straight legs of the coils, four outer inter-coil structures (OIS) and one inner inter-coil structure (IIS). The OIS consists essentially of bands around all 18 coils to provide shear support by forming shear panels with the coil case, and the IIS consists of poloidal circular keys placed directly between the coil cases. Global analysis of the 'perfect' coil shape has shown high stresses in the IIS, in the poloidal keyways. Optimization has successfully reduced these stresses to acceptable values as regards the expected fatigue resistance. However it is necessary to confirm that the stresses are still acceptable when realistic values of geometry variations are included (i.e. the effect of coil and case tolerances). Because of the extensive mechanical links between coils the poloidal key stresses can also be affected by tolerances elsewhere in the case. As the first step in assessment of the possible variations in stresses, a substructure technique is being used to develop a local model of the key region. The result of geometry variations between individual coils is a loss in the 18 fold symmetry used to simplify previous analyses. With the new and optimized model it should be possible to relax the 18-fold symmetry, but a full analysis of all 18 coils is still not possible. Systematic ways of representing the tolerance variation in the finite element model have been developed so that parametric studies can be undertaken without a full reconstruction of the model. (author)

  8. Improvements, enhancements, and optimizations of COBRA-TF

    International Nuclear Information System (INIS)

    Salko, R. K.; Avramova, M. N.; Hooper, R.; Palmtag, S.; Popov, E.; Turner, J.

    2013-01-01

    The Reactor Dynamics and Fuel Management Group (RDFMG) at The Pennsylvania State University (PSU) has become active in the Consortium for Advanced Simulation of Light Water Reactors (CASL) program by delivering, supporting, and further developing CTF, the PSU version of the Coolant Boiling in Rod Arrays - Two Fluids (COBRA-TF) Thermal/Hydraulic (T/H), sub-channel program. New development work on CTF was primarily geared towards decreasing the execution time of the code so that it may eventually be used for performing pin-by-pin, full-core simulations. Great gains have been made through targeting sections of source code for optimization. For example, wall clock time has been reduced for a one-assembly, three-dimensional model, containing ∼9,400 mesh cells, from 9.2 min to 1 min. A further improvement has been reduction in code memory usage, which was previously prohibitive for large models. In conjunction with the run time speedups, this has enabled the simulation of a refined quarter-core model (∼460,000 mesh cells), which saw a reduction in memory usage from over 130 GB to less than 3 GB. In addition to the optimization work, RDFMG has also created a preprocessor utility for the fast and less error-prone generation of CTF input decks. Furthermore, basic post-processing capabilities have been implemented by creating a CTF subroutine for producing Visualization Tool-Kit (VTK) files that output mesh data and associated simulation results. These VTK files can be opened with visualization software. (authors)

  9. TF insert experiment log book. 2nd Experiment of CS model coil

    International Nuclear Information System (INIS)

    Sugimoto, Makoto; Isono, Takaaki; Matsui, Kunihiro

    2001-12-01

    The cool down of CS model coil and TF insert was started on August 20, 2001. It took almost one month and immediately started coil charge since September 17, 2001. The charge test of TF insert and CS model coil was completed on October 19, 2001. In this campaign, total shot numbers were 88 and the size of the data file in the DAS (Data Acquisition System) was about 4 GB. This report is a database that consists of the log list and the log sheets of every shot. This is an experiment logbook for 2nd experiment of CS model coil and TF insert for charge test. (author)

  10. Inflammatory Macrophage Phenotype in BTBR T+tf/J Mice

    Directory of Open Access Journals (Sweden)

    Paul eAshwood

    2013-09-01

    Full Text Available Although autism is a behaviorally defined disorder, many studies report an association with increased pro-inflammatory cytokine production. Recent characterization of the BTBR T+tf/J (BTBR inbred mouse strain has revealed several behavioral characteristics including social deficits, repetitive behavior, and atypical vocalizations which may be relevant to autism. We therefore hypothesized that asocial BTBR mice, which exhibit autism-like behaviors, may have an inflammatory immune profile similar to that observed in children with autism. The objectives of this study were to characterize the myeloid immune profile of BTBR mice and to explore their associations with autism-relevant behaviors. C57BL/6J (C57 mice and BTBR mice were tested for social interest and repetitive self-grooming behavior. Cytokine production was measured in bone-marrow derived macrophages incubated for 24 hours in either growth media alone, LPS, IL-4/ LPS, or IFNγ/ LPS to ascertain any M1/M2 skewing. After LPS stimulation, BTBR macrophages produced higher levels of IL-6, MCP-1, and MIP-1α and lower IL-10 (p<0.01 that C57 mice, suggesting an exaggerated inflammatory profile. After exposure to IL-4/LPS BTBR macrophages produced less IL-10 than C57 macrophages and more IL-12p40 (p<0.01 suggesting poor M2 polarization. Levels of IL-12(p70 (p<0.05 were higher in BTBR macrophages after IFNγ/LPS stimulation, suggesting enhanced M1 polarization. We further observed a positive correlation between grooming frequency, and production of IL-12(p40, IL-12p70, IL-6, and TNFα (p<0.05 after treatment with IFNγ/LPS across both strains. Collectively, these data suggest that the asocial BTBR mouse strain exhibits a more inflammatory, or M1, macrophage profile in comparison to social C57 strain. We have further demonstrated a relationship between this relative increase in inflammation and repetitive grooming behavior, which may have relevance to repetitive and stereotyped behavior of autism.

  11. BOREAS TF-06 SSA-YA Surface Energy Flux and Meteorological Data

    Data.gov (United States)

    National Aeronautics and Space Administration — ABSTRACT: Contains meteorology data collected at the SSA-YA tower flux site by the TF6 group. These data were reported at 10 minute intervals. The flux and ancillary...

  12. BOREAS TF-02 SSA-OA Tethersonde Meteorological and Ozone Data

    Data.gov (United States)

    National Aeronautics and Space Administration — ABSTRACT: The BOREAS TF-02 team collected various trace gas and energy flux data along with meteorological parameters at the SSA-OA site. This data set contains...

  13. BOREAS TF-02 SSA-OA Tethersonde Meteorological and Ozone Data

    Data.gov (United States)

    National Aeronautics and Space Administration — The BOREAS TF-02 team collected various trace gas and energy flux data along with meteorological parameters at the SSA-OA site. This data set contains meteorological...

  14. Addressing safety liabilities of TfR bispecific antibodies that cross the blood-brain barrier.

    Science.gov (United States)

    Couch, Jessica A; Yu, Y Joy; Zhang, Yin; Tarrant, Jacqueline M; Fuji, Reina N; Meilandt, William J; Solanoy, Hilda; Tong, Raymond K; Hoyte, Kwame; Luk, Wilman; Lu, Yanmei; Gadkar, Kapil; Prabhu, Saileta; Ordonia, Benjamin A; Nguyen, Quyen; Lin, Yuwen; Lin, Zhonghua; Balazs, Mercedesz; Scearce-Levie, Kimberly; Ernst, James A; Dennis, Mark S; Watts, Ryan J

    2013-05-01

    Bispecific antibodies using the transferrin receptor (TfR) have shown promise for boosting antibody uptake in brain. Nevertheless, there are limited data on the therapeutic properties including safety liabilities that will enable successful development of TfR-based therapeutics. We evaluate TfR/BACE1 bispecific antibody variants in mouse and show that reducing TfR binding affinity improves not only brain uptake but also peripheral exposure and the safety profile of these antibodies. We identify and seek to address liabilities of targeting TfR with antibodies, namely, acute clinical signs and decreased circulating reticulocytes observed after dosing. By eliminating Fc effector function, we ameliorated the acute clinical signs and partially rescued a reduction in reticulocytes. Furthermore, we show that complement mediates a residual decrease in reticulocytes observed after Fc effector function is eliminated. These data raise important safety concerns and potential mitigation strategies for the development of TfR-based therapies that are designed to cross the blood-brain barrier.

  15. Individualisierte Produkte im Fokus der intergrierten Produktentwicklung

    OpenAIRE

    Baumberger, C.;Gahr, A.

    2017-01-01

    Individualisierte Produkte stellen neue Herausforderungen an die Produktentwicklung – vornehmlich im Bereich der Produktstrukturplanung, der kundenindividuellen Produktadaption und dem Zielkostenmanagement. Diese Themen werden am Lehrstuhl für Produktentwicklung im Rahmen des Sonderforschungsbereiches 582 behandelt.

  16. Application of Hadamard transform in IMS

    International Nuclear Information System (INIS)

    Sha Miaomiao; Liu Weihao; Chen Yong; Jiang Dazhen

    2008-01-01

    Hadamard transform can improve the SNR by increasing the ion duty cycle in IMS. In this paper, the ion spectral signals were processed by Hadamard transform based on the IMS detector hardware platform. The results showed that Hadamard transform can greatly improve the SNR of the IMS detector in contrast with traditional method. (authors)

  17. Advanced Interval Management (IM) Concepts of Operations

    Science.gov (United States)

    Barmore, Bryan E.; Ahmad, Nash'at N.; Underwood, Matthew C.

    2014-01-01

    This document provides a high-level description of several advanced IM operations that NASA is considering for future research and development. It covers two versions of IM-CSPO and IM with Wake Mitigation. These are preliminary descriptions to support an initial benefits analysis

  18. Argumentellipse in der "weichen" Nachricht im Deutschen und im Slowenischen

    Directory of Open Access Journals (Sweden)

    Uršula Krevs

    1998-12-01

    Full Text Available Argumentellipsen werden in der sprachlichen Kommunikation ohne weiteres akzeptiert, obwohl sie allenfalls in gewissem Sinne wegen ihrer Elliptizität abweichend wirken. Im folgenden interessiert uns, wie die Argumentellipse als syntaktische Entität in den Text eingebettet wird und welche Funktionen sie ausübt. Unsere Aufmerksamkeit gilt bier der Textsorte "weiche" Nachricht, die als Abweichung des Grundmusters gilt. Um im Sprachenpaar Deutsch-Slowenisch die in dieser Textsorte realisierten Argumentellipsen vergleichen zu können, wurde die Homogenität in der Thematik angestrebt und die Texte aus dem gleichen Kommunikationsbereich gewählt. So wurden die Korpora zwei Zeitschriften, die sich mit der gleichen Sportart beschäftigen, entnommen: der deutschen Zeitschrift "Rotpunkt" und der slowenischen Zeitschrift  "Grif '.

  19. The solar kettle-thermos flask (SK-TF) and solar vacuum tube oven

    Energy Technology Data Exchange (ETDEWEB)

    Yak, Alex Kee Koo [AkayConsult Enterprise, Johor Bahru (Malaysia)

    2008-07-01

    The Solar Kettle-Thermos Flask (SK-TF) and Solar Vacuum Tube Oven (SaVeTao): A Cost Effective, Sustainable and Renewable Water Pasteurization and Food Processing System For The Developing World. Based on the perfect solar thermal energy harvesting paradigm of maximum solar radiation absorption and minimum loss of stored converted solar thermal energy, Solar Vacuum Glass Tubes (SVGT) indefinitely delivers solar pasteurized safe drinking water, powered solely by free solar energy. The SVGT is the heart of the SK-TF. Being vacuum insulated, the SK-TF doubles up as a vacuum flask, delivering stored solar heated water in the morning before the Sun is up. With a high stagnation temperature of more than 200 C, the SK-TF can also be used for other heating purposes e.g. an oven or autoclave. Powered solely by free solar energy, the SK-TF and SaVeTaO could very well be the answer in providing safe solar pasteurized drinking water and cooking to the global poor and needy in a sustainable and renewable way. (orig.)

  20. Estimation of Theaflavins (TF) and Thearubigins (TR) Ratio in Black Tea Liquor Using Electronic Vision System

    Science.gov (United States)

    Akuli, Amitava; Pal, Abhra; Ghosh, Arunangshu; Bhattacharyya, Nabarun; Bandhopadhyya, Rajib; Tamuly, Pradip; Gogoi, Nagen

    2011-09-01

    Quality of black tea is generally assessed using organoleptic tests by professional tea tasters. They determine the quality of black tea based on its appearance (in dry condition and during liquor formation), aroma and taste. Variation in the above parameters is actually contributed by a number of chemical compounds like, Theaflavins (TF), Thearubigins (TR), Caffeine, Linalool, Geraniol etc. Among the above, TF and TR are the most important chemical compounds, which actually contribute to the formation of taste, colour and brightness in tea liquor. Estimation of TF and TR in black tea is generally done using a spectrophotometer instrument. But, the analysis technique undergoes a rigorous and time consuming effort for sample preparation; also the operation of costly spectrophotometer requires expert manpower. To overcome above problems an Electronic Vision System based on digital image processing technique has been developed. The system is faster, low cost, repeatable and can estimate the amount of TF and TR ratio for black tea liquor with accuracy. The data analysis is done using Principal Component Analysis (PCA), Multiple Linear Regression (MLR) and Multiple Discriminate Analysis (MDA). A correlation has been established between colour of tea liquor images and TF, TR ratio. This paper describes the newly developed E-Vision system, experimental methods, data analysis algorithms and finally, the performance of the E-Vision System as compared to the results of traditional spectrophotometer.

  1. Occupational safety in the nuclear power plant. The contribution of sociology to the development of a communication tool for the elimination of hazardous situations; Arbeitssicherheit im Kernkraftwerk. Der Beitrag der Sozialpsychologie zur Entwicklung eines Kommunikationsinstrumentes fuer die Behebung von Gefaehrdungssituationen

    Energy Technology Data Exchange (ETDEWEB)

    Zedler, Christien [IAOP - Institut fuer Arbeitspsychologie, Organisation und Prozessgestaltung, Berlin (Germany); Huber, Veit [E.ON Kernkraft GmbH (Germany)

    2012-11-01

    Nuclear power plant companies make efforts to enhance the operational safety in the plant. Despite a variety of measures the number of accidents at work is still too high, esp. for external personnel. Social psychological considerations were used to develop communication tools for the elimination of hazardous situations, for instance by safety dialogues between employees. The observation of hazardous situations should trigger communication and discussion on the risk of the specific situation. In the contribution practical experiences and recommendations for the realization of a safety dialogue culture in the NPP Grafenrheinfeld are summarized and illustrated by examples.

  2. Using IMS VDEX in Agrega

    Directory of Open Access Journals (Sweden)

    Jose Manuel Canabal

    2009-03-01

    Full Text Available An essential element in a learning object repository is the meta-information associated with the resources housed by the repository, as this is what enables the objects to be retrieved. In many cases, the meta-information which is described consists of the classification of a resource in relation to a taxonomy or thesaurus. Agrega is a network of learning object repositories in which an LOM profile, called LOM-ES, has been used to label the objects. Part of the meta-information described corresponds to the classification of the object with respect to a group of taxonomies and a thesaurus, which have had to be described using the ims vdex standard to enable them to be managed from the federation nodes. This article describes the way in which ims vdex has been used in order to create this description and how these metadata instances are managed.

  3. Professionalisierung und Doping im Sport

    OpenAIRE

    Wüterich, Christoph

    2004-01-01

    Der Beitrag untersucht Zusammenhänge zwischen der zunehmenden Professionalisierung des Sports und dem Anstieg von Dopingvergehen. Er zeigt, dass im historischen Vergleich beide Phänomene nicht neu sind, dass sich die Probleme aufgrund der steigenden Bedeutung des Leistungssports aber zugespitzt haben. Ausgehend von einer juristischen und sozioökonomischen Analyse der Anreize zu Doping werden Lösungsvorschläge entwickelt. The author analyzes the interdependencies between a growing commercia...

  4. The IMS Software Integration Platform

    Science.gov (United States)

    1993-04-12

    products to incorporate all data shared by the IMS applications. Some entities (time-series, images, a algorithm -specific parameters) must be managed...dbwhoanii, dbcancel Transaction Management: dbcommit, dbrollback Key Counter Assignment: dbgetcounter String Handling: cstr ~to~pad, pad-to- cstr Error...increment *value; String Maniputation: int cstr topad (array, string, arraylength) char *array, *string; int arrayjlength; int pad tocstr (string

  5. Parallelized preconditioned BiCGStab solution of sparse linear system equations in F-COBRA-TF

    International Nuclear Information System (INIS)

    Geemert, Rene van; Glück, Markus; Riedmann, Michael; Gabriel, Harry

    2011-01-01

    Recently, the in-house development of a preconditioned and parallelized BiCGStab solver has been pursued successfully in AREVA’s advanced sub-channel code F-COBRA-TF. This solver can be run either in a sequential computation mode on a single CPU, or in a parallel computation mode on multiple parallel CPUs. The developed procedure enables the computation of several thousands of successive sparse linear system solutions in F-COBRA-TF with acceptable wall clock run times. The current paper provides general information about F-COBRA-TF in terms of modeling capabilities and application areas, and points out where the relevance arises for the efficient iterative solution of sparse linear systems. Furthermore, the preconditioning and parallelization strategies in the developed BiCGStab iterative solution approach are discussed. The paper is concluded with a number of verification examples. (author)

  6. A Method to Predict Compressor Stall in the TF34-100 Turbofan Engine Utilizing Real-Time Performance Data

    Science.gov (United States)

    2015-06-01

    A METHOD TO PREDICT COMPRESSOR STALL IN THE TF34-100 TURBOFAN ENGINE UTILIZING REAL-TIME PERFORMANCE...THE TF34-100 TURBOFAN ENGINE UTILIZING REAL-TIME PERFORMANCE DATA THESIS Presented to the Faculty Department of Systems Engineering and...036 A METHOD TO PREDICT COMPRESSOR STALL IN THE TF34-100 TURBOFAN ENGINE UTILIZING REAL-TIME PERFORMANCE DATA Shuxiang ‘Albert’ Li, BS

  7. The Art and Skill of Delivering Culturally Responsive TF-CBT in Tanzania and Kenya

    Science.gov (United States)

    Kava, Christine M.; Akiba, Christopher F.; Lucid, Leah; Dorsey, Shannon

    2016-01-01

    Objective This study explored the facilitators, barriers, and strategies used to deliver a child mental health evidence-based treatment (EBT), trauma-focused cognitive behavioral therapy (TF-CBT), in a culturally responsive manner. In low- and middle-income countries most individuals with mental health problems do not receive treatment due to a shortage of mental health professionals. One approach to addressing this problem is task-sharing, in which lay counselors are trained to deliver mental health treatment. Combining this approach with a focus on EBT provides a strategy for bridging the mental health treatment gap. However, little is known how about western-developed EBTs are delivered in a culturally responsive manner. Method Semistructured qualitative interviews were conducted with 12 TF-CBT lay counselors involved in a large randomized controlled trial of TF-CBT in Kenya and Tanzania. An inductive approach was used to analyze the data. Results Lay counselors described the importance of being responsive to TF-CBT participants’ customs, beliefs, and socioeconomic conditions and highlighted the value of TF-CBT for their community. They also discussed the importance of partnering with other organizations to address unmet socioeconomic needs. Conclusion The findings from this study provide support for the acceptability and appropriateness of TF-CBT as a treatment approach for improving child mental health. Having a better understanding of the strategies used by lay counselors to ensure that treatment is relevant to the cultural and socioeconomic context of participants can help to inform the implementation of future EBTs. PMID:27414470

  8. Searching for the annual modulation of dark matter signal with the GENIUS-TF experiment

    International Nuclear Information System (INIS)

    Tomei, C.; Dietz, A.; Krivosheina, I.; Klapdor-Kleingrothaus, H.V.

    2003-01-01

    The annual modulation of the recoil spectrum observed in an underground detector is well known as the main signature of a possible WIMP signal. The GENIUS-TF experiment, under construction in the Gran Sasso National Laboratory, can search for the annual modulation of the Dark Matter signal using 40 kg of naked-Ge detectors in liquid nitrogen. Starting from a set of data simulated under the hypothesis of modulation and using different methods, we show the potential of GENIUS-TF for extracting the modulated signal and the expected WIMP mass and WIMP cross-section

  9. Impact of maximum TF magnetic field on performance and cost of an advanced physics tokamak

    International Nuclear Information System (INIS)

    Reid, R.L.

    1983-01-01

    Parametric studies were conducted using the Fusion Engineering Design Center (FEDC) Tokamak Systems Code to investigate the impact of variation in the maximum value of the field at the toroidal field (TF) coils on the performance and cost of a low q/sub psi/, quasi-steady-state tokamak. Marginal ignition, inductive current startup plus 100 s of inductive burn, and a constant value of epsilon (inverse aspect ratio) times beta poloidal were global conditions imposed on this study. A maximum TF field of approximately 10 T was found to be appropriate for this device

  10. TF.Learn: TensorFlow's High-level Module for Distributed Machine Learning

    OpenAIRE

    Tang, Yuan

    2016-01-01

    TF.Learn is a high-level Python module for distributed machine learning inside TensorFlow. It provides an easy-to-use Scikit-learn style interface to simplify the process of creating, configuring, training, evaluating, and experimenting a machine learning model. TF.Learn integrates a wide range of state-of-art machine learning algorithms built on top of TensorFlow's low level APIs for small to large-scale supervised and unsupervised problems. This module focuses on bringing machine learning t...

  11. Status of GENIUS-TF-II and TF-III-The long-term stability of naked detectors in liquid nitrogen

    Energy Technology Data Exchange (ETDEWEB)

    Klapdor-Kleingrothaus, H.V. [Max-Planck-Institut fuer Kernphysik, P.O. Box 10 39 80, D-69029 Heidelberg (Germany)]. E-mail: H.Klapdor@mpi-hd.mpg.de; Krivosheina, I.V. [Max-Planck-Institut fuer Kernphysik, P.O. Box 10 39 80, D-69029 Heidelberg (Germany)

    2006-10-15

    GENIUS-TF-II is a setup of six naked high purity Ge detectors (15kg) in liquid nitrogen in Gran Sasso. It has been installed in October, 2004-after the first four naked Ge detectors had been installed on May 5, 2003 (GENIUS-TF-I). The GENIUS-Test-Facility (GENIUS-TF) is the first and up to now only setup ever testing the novel technique aiming at extreme background reduction in search for rare decays in particular underground. The goal of GENIUS-TF was to test some key operational parameters of the full GENIUS project proposal in 1997 [H.V. Klapdor-Kleingrothaus, Int. J. Mod. Phys. A 13 (1998) 3953; H.V. Klapdor-Kleingrothaus, J. Hellmig, M. Hirsch, GENIUS-Proposal, 20 November 1997; J. Hellmig and H.V. Klapdor-Kleingrothaus, Z. Phys. A 359 ( 1997) 351 and nucl-ex/9801004; H.V. Klapdor-Kleingrothaus, M. Hirsch, Z. Phys. A 359 (1997) 361; H.V. Klapdor-Kleingrothaus, J. Hellmig, M. Hirsch, J. Phys. G 24 (1998) 483; H.V. Klapdor-Kleingrothaus, CERN Courier, November 1997, pp. 16-18]. Simultaneous physical goal is to search for the annual modulation of the Dark Matter signal [H.V. Klapdor-Kleingrothaus, et al., Nucl. Instr. and Meth. A 481 (2002) 149; C. Tomei, A. Dietz, I. Krivosheina, H.V. Klapdor-Kleingrothaus, Nucl. Instr. and Meth. 508 (2003) 343]. After operation of GENIUS-TF over three years with finally six naked Ge detectors (15kg) in liquid nitrogen in Gran Sasso we realize serious problems for realization of a full-size GENIUS-like experiment: (1) Background from Rn222 diffusing into the setup, on a level far beyond the expectation. (2) Limited long-term stability of naked detectors in liquid nitrogen as result of increasing leakage current. None of the six detectors is running after three years with the nominal leakage current. Three of the six detectors do not work any more at all. The results of our three years of investigation of the long-term stability may cast doubt on the possibility to perform full GENIUS-like projects.

  12. Status of GENIUS-TF-II and TF-III-The long-term stability of naked detectors in liquid nitrogen

    International Nuclear Information System (INIS)

    Klapdor-Kleingrothaus, H.V.; Krivosheina, I.V.

    2006-01-01

    GENIUS-TF-II is a setup of six naked high purity Ge detectors (15kg) in liquid nitrogen in Gran Sasso. It has been installed in October, 2004-after the first four naked Ge detectors had been installed on May 5, 2003 (GENIUS-TF-I). The GENIUS-Test-Facility (GENIUS-TF) is the first and up to now only setup ever testing the novel technique aiming at extreme background reduction in search for rare decays in particular underground. The goal of GENIUS-TF was to test some key operational parameters of the full GENIUS project proposal in 1997 [H.V. Klapdor-Kleingrothaus, Int. J. Mod. Phys. A 13 (1998) 3953; H.V. Klapdor-Kleingrothaus, J. Hellmig, M. Hirsch, GENIUS-Proposal, 20 November 1997; J. Hellmig and H.V. Klapdor-Kleingrothaus, Z. Phys. A 359 ( 1997) 351 and nucl-ex/9801004; H.V. Klapdor-Kleingrothaus, M. Hirsch, Z. Phys. A 359 (1997) 361; H.V. Klapdor-Kleingrothaus, J. Hellmig, M. Hirsch, J. Phys. G 24 (1998) 483; H.V. Klapdor-Kleingrothaus, CERN Courier, November 1997, pp. 16-18]. Simultaneous physical goal is to search for the annual modulation of the Dark Matter signal [H.V. Klapdor-Kleingrothaus, et al., Nucl. Instr. and Meth. A 481 (2002) 149; C. Tomei, A. Dietz, I. Krivosheina, H.V. Klapdor-Kleingrothaus, Nucl. Instr. and Meth. 508 (2003) 343]. After operation of GENIUS-TF over three years with finally six naked Ge detectors (15kg) in liquid nitrogen in Gran Sasso we realize serious problems for realization of a full-size GENIUS-like experiment: (1) Background from Rn222 diffusing into the setup, on a level far beyond the expectation. (2) Limited long-term stability of naked detectors in liquid nitrogen as result of increasing leakage current. None of the six detectors is running after three years with the nominal leakage current. Three of the six detectors do not work any more at all. The results of our three years of investigation of the long-term stability may cast doubt on the possibility to perform full GENIUS-like projects

  13. Improvements to the COBRA-TF (EPRI) computer code for steam generator analysis. Final report

    International Nuclear Information System (INIS)

    Stewart, C.W.; Barnhart, J.S.; Koontz, A.S.

    1980-09-01

    The COBRA-TF (EPRI) code has been improved and extended for pressurized water reactor steam generator analysis. New features and models have been added in the areas of subcooled boiling and heat transfer, turbulence, numerics, and global steam generator modeling. The code's new capabilities are qualified against selected experimental data and demonstrated for typical global and microscale steam generator analysis

  14. A Novel Demountable TF Joint Design for Low Aspect Ratio Spherical Torus Tokamaks

    International Nuclear Information System (INIS)

    Woolley, R.D.

    2009-01-01

    A novel shaped design for the radial conductors and demountable electrical joints connecting inner and outer legs of copper TF system conductors in low aspect ratio tokamaks is described and analysis results are presented. Specially shaped designs can optimize profiles of electrical current density, magnetic force, heating, and mechanical stress

  15. Design and implementation of quench detection instrumentation for TF magnet system of SST-1

    International Nuclear Information System (INIS)

    Khristi, Y.; Sharma, A.N.; Doshi, K.; Banaudha, M.; Prasad, U.; Varmora, P.; Patel, D.; Pradhan, S.

    2014-01-01

    Steady State Superconducting Tokamak-1 (SST-1) at Institute for Plasma Research (IPR), India is now in engineering validation phase. The assembled Toroidal Field (TF) magnet system of SST-1 will be operated at 10 kA of nominal current at helium cooled condition of 4.5 K. A reliable and fail proof quench detection (QD) system is essential for the safety and the investment protection requirements of the magnets. This QD system needs to continuously monitor all the superconducting coils, which include 16 TF magnets, return-loop, bus bars and current leads. In case of any event initiating the normal resistive zone and reaching thermal run-away, the QD system needs to trigger the magnet protection circuits. Precision instrumentation and control system with 204 signal channels had been developed for detection of quench anywhere in the entire TF magnet system. In the present configuration of quench detection scheme, the voltage drop across each double pancake (DP) of each TF coil are compared with its two adjacent DPs for the detection of normal zone and cancelation of inductive couples. Two identical redundant systems with one out of two configurations are successfully commissioned and tested at IPR. This paper describes the design and implementation of the QD system, Installation experience, validation test and initial results from the recent SST-1 magnet system charging

  16. Fabrication of new joints for SST-1 TF coil winding packs

    International Nuclear Information System (INIS)

    Prasad, Upendra; Sharma, A.N.; Patel, Dipak; Doshi, Kalpesh; Khristi, Yohan; Varmora, Pankaj; Chauhan, Pradeep; Jadeja, S.J.; Gupta, Pratibha; Pradhan, S.

    2013-01-01

    Highlights: • We have carried out work related with sub-nanoohm joints for superconducting Tokamak winding packs. • We have established fine tune QA/QC procedures for sub-nanoohm joints fabrication. • We have optimised welding parameters for cable in conduit conductors for fusion relevant magnets. • We have established precised measurement data acquisition system for low resistance measurements at cryogenic temperature. -- Abstract: The Toroidal Field (TF) magnet system of SST-1 has sixteen NbTi/Cu based coils with about one hundred Inter-Pancake (IP) and Inter-Coil (IC) joints. New box type helium leak tight, low DC resistance joints have been designed, fabricated and tested at 5 K temperature and 10 kA DC transport current. The prototype of this joint has been validated in laboratory as well as on spare TF coil winding pack. Moreover, the performance of these joints has been realised and validated on actual sixteen TF winding packs, the joint resistance of ∼0.5 nΩ repeatedly measured on hundreds of IP joints. The quality of terminations and joints was ensured at various stages of fabrication. The quality of joint box material was ensured by visual inspection, chemical analysis, radiography test, ultrasonic test, eddy current test, etc. This paper describes joint design drivers, joint design detail, prototype joint fabrication processes, quality assurance (QA)/quality control (QC) adopted during prototype and actual joint fabrication process, joint resistance measurement on actual TF coils and analysis of measured joint resistance in detail

  17. Peringkasan Sentimen Esktraktif di Twitter Menggunakan Hybrid TF-IDF dan Cosine Similarity

    Directory of Open Access Journals (Sweden)

    Devid Haryalesmana Wahid

    2016-07-01

    Full Text Available The using of Twitter by selebrities has become a new trend of impression management strategy. Mining public reaction in social media is a good strategy to obtain feedbacks, but extracting it are not trivial matter. Reads hundred of tweets while determine their sentiment polarity are time consuming. Extractive sentiment summarization machine are needed to address this issue. Previous research generally do not include sentiment information contained in a tweet as weight factor, as a results only general topics of discussion are extracted. This research aimed to do an extractive sentiment summarization on both positive and negative sentiment mentioning Indonesian selebrity, Agnes Monica, by combining SentiStrength, Hybrid TF-IDF, and Cosine Similarity. SentiStrength is used to obtain sentiment strength score and classify tweet as a positive, negative or neutral. The summarization of posisitve and negative sentiment can be done by rank tweets using Hybrid TF-IDF summarization and sentiment strength score as additional weight then removing similar tweet by using Cosine Similarity. The test results showed that the combination of SentiStrength, Hybrid TF-IDF, and Cosine Similarity perform better than using Hybrid TF-IDF only, given an average 60% accuracy and 62% f-measure. This is due to the addition of sentiment score as a weight factor in sentiment summ­ari­zation.

  18. A Novel Demountable TF Joint Design for Low Aspect Ratio Spherical Torus Tokamaks

    International Nuclear Information System (INIS)

    Woolley, Robert D.

    2009-01-01

    A novel shaped design for the radial conductors and demountable electrical joints connecting inner and outer legs of copper TF system conductors in low aspect ratio tokamaks is described and analysis results are presented. Specially shaped designs can optimize profiles of electrical current density, magnetic force, heating, and mechanical stress.

  19. BOREAS TF-8 NSA-OJP Tower Flux, Meteorological, and Soil Temperature Data

    Science.gov (United States)

    Hall, Forrest G. (Editor); Huemmrich, Karl (Editor); Moore, Kathleen E.; Fitzjarrald, David R.

    2000-01-01

    The BOREAS TF-8 team collected energy, CO2, and water vapor flux data at the BOREAS NSA-OJP site during the growing season of 1994 and most of the year for 1996. The data are available in tabular ASCII files.

  20. BOREAS TF-3 NSA-OBS Tower Flux, Meteorological, and Soil Temperature Data

    Science.gov (United States)

    Wofsy, Steven; Sutton, Doug; Goulden, Mike; Hall, Forrest G. (Editor); Huemmrich, Karl (Editor)

    2000-01-01

    The BOReal Ecosystem-Atmosphere Study Tower Flux (BOREAS TF-3) team collected tower flux, surface meteorological, and soil temperature data at the BOREAS Northern Study Area-Old Black Spruce (NSA-OBS) site continuously from the March 1994 through October 1996. The data are available in tabular ASCII files.

  1. Suchverhalten im Web: Empirische Ergebnisse

    OpenAIRE

    Schmidt-Mänz, Nadine

    2005-01-01

    Nadine Schmidt-Mänz vom Institut für Entscheidungstheorie u. Unternehmensforschung, Universität Karlsruhe, berichtete über „Suchverhalten im Web: Empirische Ergebnisse“. Rund 6000 Benutzer von Suchmaschinen füllten den von ihr hergestellten Online-Fragebogen aus. Einige ihrer Erkenntnisse: Als Suchmaschine wurde mit 91,3 % Google benutzt. Die Monopolstellung von Google war den Suchenden nicht bewußt. Einer der Schlüsse der Referentin: Es mangelt nicht an Suchmaschinen, sondern an der „Weitere...

  2. Comparative Evaluation of Tubex TF (Inhibition Magnetic Binding Immunoassay) for Typhoid Fever in Endemic Area.

    Science.gov (United States)

    Khanna, Ashish; Khanna, Menka; Gill, Karamjit Singh

    2015-11-01

    Typhoid fever remains a significant health problem in endemic countries like India. Various serological tests for the diagnosis of typhoid fever are available commercially. We assessed the usefulness of rapid test based on magnetic particle separation to detect Immunoglobulin against Salmonella typhi O9 lipopolysaccharide. Aim of this study was to compare the sensitivity and specificity of widal test, typhidot and tubex TF test for the diagnosis of typhoid fever in an endemic country like India. Serum samples collected from 50 patients of typhoid fever, 50 patients of non typhoid fever and 100 normal healthy individuals residing in Amritsar were subjected to widal test, typhidot test and tubex TF test as per manufacturer's instructions. Data collected was assessed to find sensitivity and specificity of these tests in an endemic area. Significant widal test results were found positive in 68% of patients of typhoid fever and only 4% of non typhoid fever patients. Typhidot (IgM or IgG) was positive in 72% of typhoid fever patients and 10% and 6% in non typhoid fever and normal healthy individuals respectively. Tubex TF showed higher sensitivity of 76% and specificity of 96-99% which was higher than typhidot and comparable to widal test. This was the first evaluation of rapid tubex TF test in northern India. In countries which can afford high cost of test, tubex TF should be recommended for the diagnosis in acute stage of the disease in clinical setting. However, there is urgent need for a highly specific and sensitive test for the diagnosis of typhoid fever in clinical settings in endemic areas.

  3. Digital Medien im Naturwissenschaftlichen Unterricht

    CERN Document Server

    Meßinger-Koppelt, Jenny

    2014-01-01

    „Morgens, 8 Uhr: Kurz vor der Schultür werden noch die neuesten Posts auf Facebook geliked, ein Selfie in die Whats-App-Gruppe hochgeladen oder auf YouTube noch ein #LOL-Video gestreamed. Dann klingelt es und die Digital Natives greifen wieder zu Stift, Papier und werden frontal mit Fakten gefüttert“ (A. Spang). Für Schüler sind Internet, Smartphone und Tablet-PC heute selbstverständlicher Teil ihrer Lernwelt. Und auch die Alltags- und Berufswelt ist ohne Informationstechnologien nicht mehr vorstellbar. Doch was bedeutet das für den Schulunterricht, insbesondere für die techniknahen Naturwissenschaften? Wie gelingt im Schulalltag die Balance zwischen Kreidezeit und interaktivem Whiteboard nach mittlerweile 30 Jahren Erfahrung mit Schulcomputern? Der vorliegende Sammelband präsentiert zahlreiche Praxisbeispiele aus dem Schulalltag zum sinnvollen Einsatz digitaler Medien im Biologie-, Chemie- und Physik-Unterricht sowie den aktuellen Stand der fachdidaktischen Forschung. Zu Wort kommen Hochschullehr...

  4. IMS Learning Design Frequently Asked Questions

    NARCIS (Netherlands)

    Tattersall, Colin; Manderveld, Jocelyn; Hummel, Hans; Sloep, Peter; Koper, Rob; De Vries, Fred

    2004-01-01

    This list of frequently asked questions was composed on the basis of questions asked of the Educational Technology Expertise Centrum. The questions addessed are: Where can I find the IMS Learning Design Specification? What is meant by the phrase “Learning Design”? What is the IMS LD Specification

  5. Mutation in Torenia fournieri Lind. UFO homolog confers loss of TfLFY interaction and results in a petal to sepal transformation.

    Science.gov (United States)

    Sasaki, Katsutomo; Yamaguchi, Hiroyasu; Aida, Ryutaro; Shikata, Masahito; Abe, Tomoko; Ohtsubo, Norihiro

    2012-09-01

    We identified a Torenia fournieri Lind. mutant (no. 252) that exhibited a sepaloid phenotype in which the second whorls were changed to sepal-like organs. This mutant had no stamens, and the floral organs consisted of sepals and carpels. Although the expression of a torenia class B MADS-box gene, GLOBOSA (TfGLO), was abolished in the 252 mutant, no mutation of TfGLO was found. Among torenia homologs such as APETALA1 (AP1), LEAFY (LFY), and UNUSUAL FLORAL ORGANS (UFO), which regulate expression of class B genes in Arabidopsis, only accumulation of the TfUFO transcript was diminished in the 252 mutant. Furthermore, a missense mutation was found in the coding region of the mutant TfUFO. Intact TfUFO complemented the mutant phenotype whereas mutated TfUFO did not; in addition, the transgenic phenotype of TfUFO-knockdown torenias coincided with the mutant phenotype. Yeast two-hybrid analysis revealed that the mutated TfUFO lost its ability to interact with TfLFY protein. In situ hybridization analysis indicated that the transcripts of TfUFO and TfLFY were partially accumulated in the same region. These results clearly demonstrate that the defect in TfUFO caused the sepaloid phenotype in the 252 mutant due to the loss of interaction with TfLFY. © 2012 The Authors. The Plant Journal © 2012 Blackwell Publishing Ltd.

  6. Parametric system studies of candidate TF coil system options for the Tokamak Fusion Core Experiment (TFCX)

    International Nuclear Information System (INIS)

    Reiersen, W.T.; Flanagan, C.A.; Miller, J.B.

    1983-01-01

    System studies were performed to determine the sensitivity of hybrid and superconducting toroidal field (TF) coil system options to maximum field at the TF coil and to field enhancement due to resistive insert coils. The studies were performed using Tokamak Fusion Core Experiment (TFCX) design assumptions, guidelines, and criteria and involved iterative execution of the Fusion Engineering Design Center (FEDC) systems code, magnetohydrodynamics (MHD) equilibrium code, and EFFI (a code to evaluate magnetic field strength). The results indicate that for TFCX with no minimum wall loading specified, a design point chosen solely on the basis of cost would likely be in the low-field region of design space where the cost advantage of hybrids is least apparent. However, as the desired neutron wall loading increases, the hybrid option suggests an increasing cost advantage over the all-superconducting option; this cost advantage is countered by increased complexity in design -- particularly in assembly and maintenance

  7. Shear strength of the ASDEX upgrade TF coil insulation: Rupture, fatigue and creep behaviour

    International Nuclear Information System (INIS)

    Streibl, B.; Maier, E.A.; Perchermeier, J.; Cimbrico, P.L.; Varni, G.; Pisani, D.; Deska, R.; Endreat, J.

    1987-03-01

    This report is concerned with the interlaminar shear strength of the insulation system for the 16 toroidal field (TF) coils of ASDEX upgrade. The interlaminar shear properties of the glass-epoxy insulation are primarily determined by the resin system (ARALDIT-F, HT 907, DZ 40) and its curing procedure. The pure resin was therefore tested first in tension. The results were taken into account for setting up the method of curing the TF coils. Shear tests of the complete glass-epopxy system were then conducted with tubular torque specimens providing a nearly homogeneous stress distribution. In particular, the influence of the amount of flexibilizer (5, 10, 15 parts of resin weight = PoW) on the rupture and fatigue strengths was assessed at a temperature T=60 C, as also was the temperature dependence of the creep rate (40 C, 60 C, 80 C). The results obtained are not based on safe statistics. Nevertheless, they show clear trends. (orig.)

  8. Cryogenic analysis of forced-cooled, superconducting TF magnets for compact tokamak reactors

    International Nuclear Information System (INIS)

    Kerns, J.A.; Slack, D.S.; Miller, J.R.

    1988-01-01

    Current designs for compact tokamak reactors require the toroidal- field (TF) superconducting magnets to produce fields from 10 to 15 T at the winding pack, using high-current densities to high nuclear heat loads (greater than 1 kW/coil in some instances), which are significantly greater than the conduction and radiation heat loads for which cryogenic systems are usually designed. A cryogenic system for the TF winding pack for two such tokamak designs has been verified by performing a detailed, steady-state heat-removal analysis. Helium properties along the forced-cooled conductor flow path for a range of nuclear heat loads have been calculated. The results and implications of this analysis are presented. 12 refs., 6 figs

  9. Parametric system studies of candidate TF coil system options for the Tokamak Fusion Core Experiment (TFCX)

    International Nuclear Information System (INIS)

    Reiersen, W.T.; Flanagan, C.A.; Miller, J.B.

    1983-01-01

    System studies were performed to determine the sensitivity of hybrid and superconducting toroidal field (TF) coil system options to maximum field at the TF coil and to field enhancement due to resistive insert coils. The studies were performed using Tokamak Fusion Core Experiment (TFCX) design assumptions, guidelines, and criteria and involved iterative execution of the Fusion Engineering Design Center (FEDC) systems code, magnetohydrodynamics (MHD) equilibrium code, and EFFI (a code to evaluate magnetic field strength). The results indicate that for TFCX with no minimum wall loading specified, a design point chosen solely on the basis of cost would likely be in the low-field region of design space where the cost advantage of hybrids is least apparent. However, as the desired neutron wall loading increases, the hybrid option suggests an increasing cost advantage over the all-superconducting option; this cost advantage is countered by increased complexity in design - particularly in assembly and maintenance

  10. Qualification of the US Made Conductors for ITER TF Magnet System

    International Nuclear Information System (INIS)

    Martovetsky, Nicolai N.; Hatfield, Daniel R.; Miller, John R.; Bruzzone, P.; Stepanov, B.; Seber, B.

    2010-01-01

    The US Domestic Agency (USDA) is one of the six suppliers of the Toroidal Field (TF) conductor for the International Thermonuclear Experimental Reactor (ITER). In order to qualify conductors according to ITER requirements we prepared several lengths of the CICC and short samples for testing in the SULTAN facility in CRPP, Switzerland. We also fully characterized the strands that were used in these SULTAN samples. Fabrication experience and test results are presented and discussed.

  11. Two-phase interfacial area and flow regime modeling in FLOWTRAN-TF code

    International Nuclear Information System (INIS)

    Smith, F.G. III; Lee, S.Y.; Flach, G.P.; Hamm, L.L.

    1992-01-01

    FLOWTRAN-TF is a new two-component, two-phase thermal-hydraulics code to capture the detailed assembly behavior associated with loss-of-coolant accident analyses in multichannel assemblies of the SRS reactors. The local interfacial area of the two-phase mixture is computed by summing the interfacial areas contributed by each of three flow regimes. For smooth flow regime transitions, the code uses an interpolation technique in terms of component void fraction for each basic flow regime

  12. A Follow-Up Study from a Multisite, Randomized Controlled Trial for Traumatized Children Receiving TF-CBT.

    Science.gov (United States)

    Jensen, Tine K; Holt, Tonje; Ormhaug, Silje M

    2017-11-01

    Trauma-focused cognitive behavioral therapy (TF-CBT) is the treatment of choice for traumatized youth, however, follow-up studies are scarce, and treatment effects for co-occurring depression show mixed findings. The aims of this study were to examine whether treatment effects of TF-CBT are maintained at 18 month follow-up and whether degree of co-occurring depression influences treatment effects. As rapid improvement in psychological functioning is warranted for youth, we also investigated whether the symptom trajectory was different for TF-CBT compared to therapy as usual (TAU). The sample consisted of 156 youth (M age = 15.05, 79.50% girls) randomly assigned to TF-CBT or TAU. The youth were assessed for posttraumatic stress symptoms (PTSS), depression, anxiety and general mental health symptoms. Mixed effects analyses followed the symptom courses over 5 time points. Youth receiving TF-CBT maintained their symptom improvement at 18 months follow-up with scores below clinical cut-of on all symptom measures. The most depressed youth had also a significant decline in symptoms that were maintained at follow-up. Symptom trajectories differed as the TF-CBT group reported a more rapid symptom reduction compared to the TAU condition. In the TAU condition, participants received 1.5 times the number of treatment sessions compared to the TF-CBT participants. After 18 months the groups were significantly different on general mental health symptoms only. In conclusion, youth receiving TF-CBT experienced more efficient improvement in trauma related symptoms than youth receiving TAU and these improvements were maintained after 18 months. Also youth experiencing serious co-occurring depression benefitted from TF-CBT.

  13. From data repositories to submission portals: rethinking the role of domain-specific databases in CollecTF.

    Science.gov (United States)

    Kılıç, Sefa; Sagitova, Dinara M; Wolfish, Shoshannah; Bely, Benoit; Courtot, Mélanie; Ciufo, Stacy; Tatusova, Tatiana; O'Donovan, Claire; Chibucos, Marcus C; Martin, Maria J; Erill, Ivan

    2016-01-01

    Domain-specific databases are essential resources for the biomedical community, leveraging expert knowledge to curate published literature and provide access to referenced data and knowledge. The limited scope of these databases, however, poses important challenges on their infrastructure, visibility, funding and usefulness to the broader scientific community. CollecTF is a community-oriented database documenting experimentally validated transcription factor (TF)-binding sites in the Bacteria domain. In its quest to become a community resource for the annotation of transcriptional regulatory elements in bacterial genomes, CollecTF aims to move away from the conventional data-repository paradigm of domain-specific databases. Through the adoption of well-established ontologies, identifiers and collaborations, CollecTF has progressively become also a portal for the annotation and submission of information on transcriptional regulatory elements to major biological sequence resources (RefSeq, UniProtKB and the Gene Ontology Consortium). This fundamental change in database conception capitalizes on the domain-specific knowledge of contributing communities to provide high-quality annotations, while leveraging the availability of stable information hubs to promote long-term access and provide high-visibility to the data. As a submission portal, CollecTF generates TF-binding site information through direct annotation of RefSeq genome records, definition of TF-based regulatory networks in UniProtKB entries and submission of functional annotations to the Gene Ontology. As a database, CollecTF provides enhanced search and browsing, targeted data exports, binding motif analysis tools and integration with motif discovery and search platforms. This innovative approach will allow CollecTF to focus its limited resources on the generation of high-quality information and the provision of specialized access to the data.Database URL: http://www.collectf.org/. © The Author(s) 2016

  14. Non Nuclear Testing of Reactor Systems In The Early Flight Fission Test Facilities (EFF-TF)

    International Nuclear Information System (INIS)

    Van Dyke, Melissa; Martin, James

    2004-01-01

    The Early Flight Fission-Test Facility (EFF-TF) can assist in the design and development of systems through highly effective non-nuclear testing of nuclear systems when technical issues associated with near-term space fission systems are 'non-nuclear' in nature (e.g. system's nuclear operations are understood). For many systems, thermal simulators can be used to closely mimic fission heat deposition. Axial power profile, radial power profile, and fuel pin thermal conductivity can be matched. In addition to component and subsystem testing, operational and lifetime issues associated with the steady state and transient performance of the integrated reactor module can be investigated. Instrumentation at the EFF-TF allows accurate measurement of temperature, pressure, strain, and bulk core deformation (useful for accurately simulating nuclear behavior). Ongoing research at the EFF-TF is geared towards facilitating research, development, system integration, and system utilization via cooperative efforts with DOE laboratories, industry, universities, and other Nasa centers. This paper describes the current efforts for the latter portion of 2003 and beginning of 2004. (authors)

  15. A new meshless approach to map electromagnetic loads for FEM analysis on DEMO TF coil system

    International Nuclear Information System (INIS)

    Biancolini, Marco Evangelos; Brutti, Carlo; Giorgetti, Francesco; Muzzi, Luigi; Turtù, Simonetta; Anemona, Alessandro

    2015-01-01

    Graphical abstract: - Highlights: • Generation and mapping of magnetic load on DEMO using radial basis function. • Good agreement between RBF interpolation and EM TOSCA computations. • Resultant forces are stable with respect to the target mesh used. • Stress results are robust and accurate even if a coarse cloud is used for RBF interpolation. - Abstract: Demonstration fusion reactors (DEMO) are being envisaged to be able to produce commercial electrical power. The design of the DEMO magnets and of the constituting conductors is a crucial issue in the overall engineering design of such a large fusion machine. In the frame of the EU roadmap of the so-called fast track approach, mechanical studies of preliminary DEMO toroidal field (TF) coil system conceptual designs are being enforced. The magnetic field load acting on the DEMO TF coil conductor has to be evaluated as input in the FEM model mesh, in order to evaluate the stresses on the mechanical structure. To gain flexibility, a novel approach based on the meshless method of radial basis functions (RBF) has been implemented. The present paper describes this original and flexible approach for the generation and mapping of magnetic load on DEMO TF coil system.

  16. Design considerations for the TF center conductor post for the Ignition Spherical Torus (IST)

    International Nuclear Information System (INIS)

    Dalton, G.R.; Haines, J.R.

    1986-01-01

    A trade-off study has been carried out to compare the differential costs of using high-strength alloy copper versus oxygen-free, high-conductivity (OFHC) copper for the center legs of the toroidal field (TF) coils of an Ignition Spherical Torus (IST). The electrical heating, temperatures, stresses, cooling requirements, material costs, pump costs, and power to drive the TF coils and pumps are all assessed for both materials for a range of compact tokamak reactors. The alloy copper material is found to result in a more compact reactor and to allow use of current densities of up to 170 MA/m 2 versus 40 MA/m 2 for the OFHC copper. The OFHC conductor system with high current density is $24 million less expensive than more conventional copper systems with 30 MA/m 2 . The alloy copper system costs $32 million less than conventional systems. Therefore, the alloy system offers a net savings of $8 million compared to the 50% cold-worked OFHC copper system. Although the savings are a significant fraction of the center conductor post cost, they are relatively insignificant in terms of the total device cost. It is concluded that the use of alloy copper contributes very little to the economic or technical viability of the compact IST. It is recommended that a similar systematic approach be applied to evaluating coil material and current density trade-offs for other compact copper-TF-coil tokamak designs. 9 refs., 13 figs., 13 tabs

  17. Fatigue assessment of the ITER TF coil case based on JJ1 fatigue tests

    International Nuclear Information System (INIS)

    Hamada, K.; Nakajima, H.; Takano, K.; Kudo, Y.; Tsutsumi, F.; Okuno, K.; Jong, C.

    2005-01-01

    The material of the TF coil case in the ITER requires to withstand cyclic electromagnetic forces applied up to 3 x 10 4 cycles at 4.2 K. A cryogenic stainless steel, JJ1, is used in high stress region of TF coil case. The fatigue characteristics (S-N curve) of JJ1 base metal and welded joint at 4.2 K has been measured. The fatigue strength of base metal and welded joint at 3 x 10 4 cycles are measured as 1032 and 848 MPa, respectively. The design S-N curve is derived from the measured data taking account of the safety factor of 20 for cycle-to-failure and 2 for fatigue strength, and it indicates that an equivalent alternating stress of the case should be kept less than 516 MPa for the base metal and 424 MPa for the welded joint at 3 x 10 4 cycles. It is demonstrated that the TF coil case has enough margins for the cyclic operation. It is also shown the welded joint should be located in low cyclic stress region because a residual stress affects the fatigue life

  18. Full scale trials for qualification of the manufacture of the ITER TF coils in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Matsui, Kunihiro, E-mail: matsui.kunihiro@jaea.go.jp; Hemmi, Tsutomu; Kajitani, Hideki; Yamane, Minoru; Mizutani, Takumi; Nakano, Toshihide; Takano, Katsutoshi; Ando, Shinji; Koizumi, Norikiyo

    2016-11-01

    Highlights: • High accuracy conductor winding of 0.1% was achieved in TF coil fabrication. • Conductor elongation due to heat treatment satisfied with the expected value of 0.06% ± 0.02%. • Commissioning of a transfer tooling without adding strain to conductor was completed. • Commissioning of a conductor insulation and CP welding was successfully completed. - Abstract: JAEA performed full-scale trials to qualify and optimize manufacturing procedure of TF coil fabrication prior to series production. In the full-scale trials, conductor winding, heat treatment, conductor transfer, conductor insulation and cover plate (CP) welding trials were performed to resolve some technical issues and to demonstrate the fabrication procedure. The followings are major achievement. (1) High accuracy conductor winding of 0.01%, (2) the evaluation of 0.06% conductor elongation due to heat treatment, (3) conductor transfer in a radial plate (RP) groove with addition strain under 0.1%, (4) conductor insulation without breakage of the insulation tape and (5) flatness of 2 mm of the double pancake (DP) by CP welding. Then JAEA started the 1st TF coil fabrication from March 2014, and has already completed ten conductor windings and heat treatment of nine windings.

  19. E2eUberIM

    DEFF Research Database (Denmark)

    Wac, Katarzyna; Cummings, Mark; Dey, Jayanta

    2016-01-01

    , high-quality services, we propose an innovative end-to-end service management framework called e2eUberIM. This framework contains a scalable, flexible, and volatile information model (UberIM) and a real-time, "organic" communication and storage process (e2eUber). It leverages the proprietary interfaces...... of different vendors, enabling the resulting enhanced operations system environment to automatically and in real-time optimize operational overhead while maximizing the user experience, and quickly field new innovative, composed "any-services" (XaaS). We document the e2eUberIM requirements and its design...

  20. Imágenes e identidades

    OpenAIRE

    Guerrini, Sebastión

    2013-01-01

    Las identidades se estructuran en un proceso de identificación continua con imágenes. Esto afecta no solo a las identidades de las personas, sino también a las de las instituciones, organizaciones y empresas. En este sentido, el rol de ser del Diseño en Comunicación Visual es intentar afectar a las identidades de los espectadores de sus imágenes. Por esta razón, primero es importante definir qué son las imágenes. Facultad de Bellas Artes

  1. I'm a Map, I'm a Green Tree

    Science.gov (United States)

    Anderson, Daniel

    2010-01-01

    I'm talking about the ways we represent ourselves and our world. I've put some thoughts on the topic together here--a gathering that enacts new media creating and takes up conceptual layers like metaphors, models, and composing. The primary sources are videos from the Get a Mac campaign, aka I'm a Mac; I'm a PC ads. Posthuman concepts blending…

  2. Innovationsmanagement im Marketing: Anleitung zur Innovations-Sensibilisierung und deren Umsetzung im Rahmen der Neuen Lernkultur

    OpenAIRE

    Mangisch, Christian; Blatter, Martin

    2009-01-01

    Der Kurs “Innovationsmanagement im Marketing“ vermittelt den Teilnehmenden Wissen zum Innovationsmanagement, zum innovativen Team und zu innovativen Marketing Trends. Diese Kurse sind online auf dem folgenden Link www.ritzycampus.ch zu finden. Die Teilnehmer müssen für den Online-Kurs keine speziellen Kenntnisse oder Voraussetzungen mitbringen. Diese Online-Kurse im Fach Marketing sind an ein breites Publikum gerichtet. Sie ermöglichen den Studierenden im Eigenstudium die Grundlagen der Theme...

  3. IMS Mitigation Target Areas - 2010 [ds673

    Data.gov (United States)

    California Natural Resource Agency — Mitigation Target Areas (MTA) were developed by the California Department of Fish and Game for the Interim Mitigation Strategy (IMS). The MTAs are an identification...

  4. [Variation im heutigen Deutsch...] / Laura Tidrike

    Index Scriptorium Estoniae

    Tidrike, Laura

    2008-01-01

    Arvustus: Variation im heutigen Deutsch : Perspektiven für den Sprachunterricht / hrsg. v. Eva Neuland. Frankfurt am Main : Lang, 2006. (Sprache - Kommunikation - Kultur. Soziolinguistische Beiträge ; Vol. 4)

  5. Literatur zu Gast im Globe

    CERN Multimedia

    2006-01-01

    Der deutsche Schriftsteller Thomas LEHR liest am 23. März 2006 aus seinem Roman '42', einem philosophischen Abenteuerroman über die Suche nach der Zeit, erzählt in einer funkelnden und souveränen Sprache. Eine Welt von vernichtender Schönheit und bizarren Schrecken wartet auf eine Besuchergruppe, die in der Nähe von Genf die unterirdischen Anlagen des Forschungszentrums für Teilchenphysik CERN besichtigt. Als sie um 12:47:42 wieder ans Tageslicht tritt, scheint ganz Europa in einen Dornröschenschlaf gefallen. Allein die 70 Besucher können sich noch bewegen. Monate und Jahre verharrt die Welt wie in einer riesigen dreidimensionalen Fotografie, bis ein wiederum schockierendes Ereignis die 'Chronifizierten' aus ihren physikalischen Spekulationen und seltsamen Lebensformen reisst. Zu dieser literarischen Veranstaltung im 'Globe of Science and Innovation' laden gemeinsam das Generalkonsulat der Bundesrepublik Deutschland in Genf und CERN ein. Vor Beginn der Lesung wird eine Führung in deutscher Sprac...

  6. Gruppenbezogene Menschenfeindlichkeit im Sport in Brandenburg

    OpenAIRE

    Delto, Hannes; Tzschoppe, Petra

    2016-01-01

    Mit der Querschnittsstudie "Wir und die Anderen – Gruppenbezogene Menschenfeindlichkeit im organisierten Sport in Brandenburg" wurde das Syndrom Gruppenbezogener Menschenfeindlichkeit im organisierten Sport untersucht. Das Konzept der Gruppenbezogenen Menschenfeindlichkeit – ausgehend von einer Ideologie der Ungleichwertigkeit – wurde von Prof. Wilhelm Heitmeyer (Universität Bielefeld) entwickelt. Die Ergebnisse ermöglichen explizite Aussagen über Ausmaß und Ursachen Gruppenbezogener Menschen...

  7. Gruppenbezogene Menschenfeindlichkeit im Sport in Sachsen

    OpenAIRE

    Delto, Hannes; Tzschoppe, Petra

    2015-01-01

    Mit der Querschnittsstudie „Wir und die Anderen – Gruppenbezogene Menschenfeindlichkeit im organisierten Sport in Sachsen“ wurde erstmals das Syndrom Gruppenbezogener Menschenfeindlichkeit im organisierten Sport untersucht. Das Konzept der Gruppenbezogenen Menschenfeindlichkeit – ausgehend von einer Ideologie der Ungleichwertigkeit – wurde von Prof. Wilhelm Heitmeyer (Universität Bielefeld) entwickelt. Die Ergebnisse ermöglichen explizite Aussagen über Ausmaß und Ursachen Gruppenbezogener Men...

  8. Verletzungen und Fehlbeanspruchungen im leistungsorientierten Rudersport

    OpenAIRE

    Bussian, Marc Robert

    2004-01-01

    Die Stellung der Breitensportart Rudern als gesundheitsfördernde Sportform ist in der Literatur gleichlautend positiv beschrieben. Im leistungsorientierten Rudersport müssen neben den Verletzungen und Fehlbeanspruchungen der eigentlichen Sportart die unabdingbaren Nebentrainingsformen berücksichtigt werden. In den neunziger Jahren vollzog sich ein trainingsmethodischer Wandel, die Einführung eines erschwinglichen Rudersimulators und eine technische Weiterentwicklung im Boots- und Ruderbau. Ei...

  9. GENIUS and the Genius TF: A New Observatory for WIMP Dark Matter and Neutrinoless Double Beta Decay

    OpenAIRE

    Klapdor-Kleingrothaus, H. V.; Majorovits, B.

    2001-01-01

    The GENIUS proposal is described and some of it's physics potential is outlined. Also in the light of the contradictive results from the DAMA and CDMS experiments the Genius TF, a new experimental setup is proposed. The Genius TF could probe the DAMA evidence region using the WIMP nucleus recoil signal and WIMP annual modulation signature simultaneously. Besides that it can prove the long term feasibility of the detector technique to be implemented into the GENIUS setup and will in this sense...

  10. Engineering, Manufacture and Preliminary Testing of the ITER Toroidal Field (TF) Magnet Helium Cold Circulator

    Science.gov (United States)

    Rista, P. E. C.; Shull, J.; Sargent, S.

    2015-12-01

    The ITER cryodistribution system provides the supercritical Helium (SHe) forced flow cooling to the magnet system using cold circulators. The cold circulators are located in each of five separate auxiliary cold boxes planned for use in the facility. Barber-Nichols Inc. has been awarded a contract from ITER-India for engineering, manufacture and testing of the Toroidal Field (TF) Magnet Helium Cold Circulator. The cold circulator will be extensively tested at Barber-Nichols’ facility prior to delivery for qualification testing at the Japan Atomic Energy Agency's (JAEA) test facility at Naka, Japan. The TF Cold Circulator integrates features and technical requirements which Barber-Nichols has utilized when supplying helium cold circulators worldwide over a period of 35 years. Features include a vacuum-jacketed hermetically sealed design with a very low helium leak rate, a heat shield for use with both nitrogen & helium cold sources, a broad operating range with a guaranteed isentropic efficiency over 70%, and impeller design features for high efficiency. The cold circulator will be designed to meet MTBM of 17,500 hours and MTBF of 36,000 hours. Vibration and speed monitoring are integrated into a compact package on the rotating assembly with operation and health monitoring in a multi-drop PROFIBUS communication environment using an electrical cabinet with critical features and full local and network PLC interface and control. For the testing in Japan and eventual installation in Europe, the cold circulator must be certified to the Japanese High Pressure Gas Safety Act (JHPGSA) and CE marked in compliance with the European Pressure Equipment Directive (PED) including Essential Safety Requirements (ESR). The test methodology utilized at Barber-Nichols’ facility and the resulting test data, validating the high efficiency of the TF Cold Circulator across a broad operating range, are important features of this paper.

  11. Engineering, Manufacture and Preliminary Testing of the ITER Toroidal Field (TF) Magnet Helium Cold Circulator

    International Nuclear Information System (INIS)

    C Rista, P E; Shull, J; Sargent, S

    2015-01-01

    The ITER cryodistribution system provides the supercritical Helium (SHe) forced flow cooling to the magnet system using cold circulators. The cold circulators are located in each of five separate auxiliary cold boxes planned for use in the facility. Barber-Nichols Inc. has been awarded a contract from ITER-India for engineering, manufacture and testing of the Toroidal Field (TF) Magnet Helium Cold Circulator. The cold circulator will be extensively tested at Barber-Nichols’ facility prior to delivery for qualification testing at the Japan Atomic Energy Agency's (JAEA) test facility at Naka, Japan. The TF Cold Circulator integrates features and technical requirements which Barber-Nichols has utilized when supplying helium cold circulators worldwide over a period of 35 years. Features include a vacuum-jacketed hermetically sealed design with a very low helium leak rate, a heat shield for use with both nitrogen and helium cold sources, a broad operating range with a guaranteed isentropic efficiency over 70%, and impeller design features for high efficiency. The cold circulator will be designed to meet MTBM of 17,500 hours and MTBF of 36,000 hours. Vibration and speed monitoring are integrated into a compact package on the rotating assembly with operation and health monitoring in a multi-drop PROFIBUS communication environment using an electrical cabinet with critical features and full local and network PLC interface and control. For the testing in Japan and eventual installation in Europe, the cold circulator must be certified to the Japanese High Pressure Gas Safety Act (JHPGSA) and CE marked in compliance with the European Pressure Equipment Directive (PED) including Essential Safety Requirements (ESR). The test methodology utilized at Barber-Nichols’ facility and the resulting test data, validating the high efficiency of the TF Cold Circulator across a broad operating range, are important features of this paper. (paper)

  12. CardioTF, a database of deconstructing transcriptional circuits in the heart system.

    Science.gov (United States)

    Zhen, Yisong

    2016-01-01

    Information on cardiovascular gene transcription is fragmented and far behind the present requirements of the systems biology field. To create a comprehensive source of data for cardiovascular gene regulation and to facilitate a deeper understanding of genomic data, the CardioTF database was constructed. The purpose of this database is to collate information on cardiovascular transcription factors (TFs), position weight matrices (PWMs), and enhancer sequences discovered using the ChIP-seq method. The Naïve-Bayes algorithm was used to classify literature and identify all PubMed abstracts on cardiovascular development. The natural language learning tool GNAT was then used to identify corresponding gene names embedded within these abstracts. Local Perl scripts were used to integrate and dump data from public databases into the MariaDB management system (MySQL). In-house R scripts were written to analyze and visualize the results. Known cardiovascular TFs from humans and human homologs from fly, Ciona, zebrafish, frog, chicken, and mouse were identified and deposited in the database. PWMs from Jaspar, hPDI, and UniPROBE databases were deposited in the database and can be retrieved using their corresponding TF names. Gene enhancer regions from various sources of ChIP-seq data were deposited into the database and were able to be visualized by graphical output. Besides biocuration, mouse homologs of the 81 core cardiac TFs were selected using a Naïve-Bayes approach and then by intersecting four independent data sources: RNA profiling, expert annotation, PubMed abstracts and phenotype. The CardioTF database can be used as a portal to construct transcriptional network of cardiac development. Database URL: http://www.cardiosignal.org/database/cardiotf.html.

  13. Conference on heat mass transfer and properties of liquid metals TF-2002

    International Nuclear Information System (INIS)

    Efanov, A.D.; Kozlov, F.A.

    2003-01-01

    Results of the conference TF-2002 devoted to the combined approach to problems of harnessing liquid metals as coolants for NPU are presented. The conference takes place in Obninsk, 29 - 31 October, 2002. Papers of the conference involve items on thermal hydraulics, mass transfer and safety of NPU with liquid metal coolants, structure, physical and chemical properties of liquid metal and liquid metal solutions, decommissioning of units and ecology, application of liquid metals divorced with NPU. Most of the papers of the conference are devoted to the investigation into lead and lead-bismuth coolants [ru

  14. Solvent extraction of Pu(IV) with TODGA in C6mimTf2N

    International Nuclear Information System (INIS)

    Xiaohong Huang; Qiuyue Zhang; Jinping Liu; Hui He; Wenbin Zhu; Xiaorong Wang

    2013-01-01

    Studies on the solvent extraction of Plutonium(Pu(IV)) from aqueous nitric acid by N,N,N'N'tetraoctyl-diglycolamide (TODGA) in 1-hexyl-3-methylimidazolium-bis(trifluoromethylsulfonyl) imide (C 6 mimTf 2 N) room temperature ionic liquid (RTIL) were carried out. It was found that Pu(IV) is extracted into RTIL phase as [Pu(NO 3 )(TODGA)] 3+ through cation exchange mechanism. Extraction reaction equation is obtained by the influence of acidity and extractant concentration, and the parameters of thermodynamic equilibrium constant was calculated. (author)

  15. tf_unet: Generic convolutional neural network U-Net implementation in Tensorflow

    Science.gov (United States)

    Akeret, Joel; Chang, Chihway; Lucchi, Aurelien; Refregier, Alexandre

    2016-11-01

    tf_unet mitigates radio frequency interference (RFI) signals in radio data using a special type of Convolutional Neural Network, the U-Net, that enables the classification of clean signal and RFI signatures in 2D time-ordered data acquired from a radio telescope. The code is not tied to a specific segmentation and can be used, for example, to detect radio frequency interference (RFI) in radio astronomy or galaxies and stars in widefield imaging data. This U-Net implementation can outperform classical RFI mitigation algorithms.

  16. BOREAS TF-8 NSA-OJP and SSA-OBS Ceilometer Data

    Science.gov (United States)

    Moore, Kathleen E.; Hall, Forrest G. (Editor); Huemmrich, Karl (Editor); Fitzjarrald, David R.

    2000-01-01

    The BOREAS TF-8 team used ceilometers to collect data on the fraction of the sky covered with clouds and the cloud height. Included with these data is the surface-based lifting condensation level, derived from temperature and humidity values acquired at the flux tower at the NSA-OJP site. Ceilo-meter data were collected at the NSA-OJP site in 1994 and at the NSA-OJP and SSA-OBS sites in 1996. The data are available in tabular ASCII files. The data files are available on a CD-ROM (see document number 20010000884).

  17. Integrating IMS LD and IMS QTIv2 using CopperCore Service Integration

    NARCIS (Netherlands)

    Vogten, Hubert

    2006-01-01

    Vogten, H. (2006). Integrating IMS LD and IMS QTIv2 using CopperCore Service Integration. Presentation at International Workshop in Learning Networks for Lifelong Competence Development. March, 30-31, 2006. Sofia, Bulgaria: TENCompetence Conference. Retrieved June 30th, 2006, from

  18. CopperCore Service Integration, Integrating IMS Learning Design and IMS Question and Test Interoperability

    NARCIS (Netherlands)

    Vogten, Hubert; Martens, Harrie; Nadolski, Rob; Tattersall, Colin; Van Rosmalen, Peter; Koper, Rob

    2006-01-01

    Vogten, H., Martens, H., Nadolski, R., Tattersall, C., Rosmalen, van, P., Koper, R., (2006). CopperCore Service Integration, Integrating IMS Learning Design and IMS Question and Test Interoperability. Proceedings of the 6th IEEE International Conference on Advanced Learning Technologies (pp.

  19. Integrating IMS Learning Design and IMS Question and Test Interoperability using CopperCore Service Integration

    NARCIS (Netherlands)

    Vogten, Hubert; Martens, Harrie; Nadolski, Rob; Tattersall, Colin; Van Rosmalen, Peter; Koper, Rob

    2006-01-01

    Please, cite this publication as: Vogten, H., Martens, H., Nadolski, R., Tattersall, C., van Rosmalen, P., & Koper, R. (2006). Integrating IMS Learning Design and IMS Question and Test Interoperability using CopperCore Service Integration. Proceedings of International Workshop in Learning Networks

  20. Cis-regulatory control of the nuclear receptor Coup-TF gene in the sea urchin Paracentrotus lividus embryo.

    Directory of Open Access Journals (Sweden)

    Lamprini G Kalampoki

    Full Text Available Coup-TF, an orphan member of the nuclear receptor super family, has a fundamental role in the development of metazoan embryos. The study of the gene's regulatory circuit in the sea urchin embryo will facilitate the placement of this transcription factor in the well-studied embryonic Gene Regulatory Network (GRN. The Paracentrotus lividus Coup-TF gene (PlCoup-TF is expressed throughout embryonic development preferentially in the oral ectoderm of the gastrula and the ciliary band of the pluteus stage. Two overlapping λ genomic clones, containing three exons and upstream sequences of PlCoup-TF, were isolated from a genomic library. The transcription initiation site was determined and 5' deletions and individual segments of a 1930 bp upstream region were placed ahead of a GFP reporter cassette and injected into fertilized P.lividus eggs. Module a (-532 to -232, was necessary and sufficient to confer ciliary band expression to the reporter. Comparison of P.lividus and Strongylocentrotus purpuratus upstream Coup-TF sequences, revealed considerable conservation, but none within module a. 5' and internal deletions into module a, defined a smaller region that confers ciliary band specific expression. Putative regulatory cis-acting elements (RE1, RE2 and RE3 within module a, were specifically bound by proteins in sea urchin embryonic nuclear extracts. Site-specific mutagenesis of these elements resulted in loss of reporter activity (RE1 or ectopic expression (RE2, RE3. It is proposed that sea urchin transcription factors, which bind these three regulatory sites, are necessary for spatial and quantitative regulation of the PlCoup-TF gene at pluteus stage sea urchin embryos. These findings lead to the future identification of these factors and to the hierarchical positioning of PlCoup-TF within the embryonic GRN.

  1. Preliminary power supply design for the TF coil system of CIT

    International Nuclear Information System (INIS)

    Neumeyer, C.; Bronner, G.; Huttar, D.

    1989-01-01

    Initial operation of the Compact Ignition Tokamak (CIT) is planned with a Toroidal Field (TF) of 8 Tesla and a flat top duration of 5 seconds. Ultimately, operation will be extended beyond 8 Tesla. The power supply to be used for the initial phase of operation has been modeled using the parameters of the thyristor rectifier power supplies which are now in service for the Tokamak Fusion Test Reactor (TFTR). A subset of these existing units, or perhaps new units with similar ratings, are envisioned to be connected to the existing 138kV transmission line serving PPPL so as to take advantage of this power source for CIT. For the extended operation phase the equipment used for the initial phase of TF operation will be augmented with new equipment to permit operation up to 11 Tesla. This paper describes the preliminary design for the 8 Tesla power supply and presents results from simulation studies. In addition, issues concerning transient behavior and fault modes are discussed. 4 refs., 12 figs

  2. Parametric thermo-hydraulic analysis of the TF system of JT-60SA during fast discharge

    International Nuclear Information System (INIS)

    Polli, Gian Mario; Lacroix, Benoit; Zani, Louis; Besi Vetrella, Ugo; Cucchiaro, Antonio

    2013-01-01

    Highlights: • We modeled the central clock-wise pancake of JT-60SA TF magnet at the EOB. • We simulated a quench followed by a fast discharge. • We evaluated the temperature and pressure rises in the nominal configuration. • We evaluated the effect of several parameter changes on the thermal-hydraulic response of the system. -- Abstract: The evolution of the conductor temperature and of the helium pressure of the central pancake of the TF superconducting magnet of the JT-60SA tokamak in a quench scenario are here discussed. The quench is triggered by a heat disturbance applied at the end of burning and followed by a fast safety discharge. A parametric study aimed at assessing the robustness of the calculation is also addressed with special regard to the voltage threshold, used to define the occurrence of the quench, and to the time delay, that cover all the possible delays in the fast discharge after quench detection. Finally, due to sensitivity analyses the influences of different parameters were assessed: the material properties of the strands (RRR, copper fraction), the magnitude and the spatial length of the triggering disturbance and the magnetic field distribution. The numerical evaluations were performed in the framework of the Broader Approach Agreement in collaboration with CEA, ENEA and the JT-60SA European Home Team using the 1D code Gandalf [1

  3. Stability of [MeBu3N][Tf2N] under gamma irradiation

    International Nuclear Information System (INIS)

    Bosse, Emilie; Berthon, Laurence; Zorz, Nicole; Monget, Julie; Berthon, Claude; Bisel, Isabelle; Legand, Solene; Moisy, Philippe

    2008-01-01

    The stability of the ionic liquid [MeBu 3 N][Tf 2 N], dry or after contact with water (where [MeBu 3 N] + is the methyl-tributyl-ammonium cation and [Tf 2 N] - is the bistriflimide anion), was studied under 137 Cs gamma irradiation in argon and in air. In a quantitative study with an absorbed dose of 2 MGy this ionic liquid was highly stable regardless of the radiolysis conditions. The radiolytic disappearance yields determined by ESI-MS were -0.38 and -0.25 μmol*J -1 for the cation and anion, respectively. ESI-MS, NMR, and liquid chromatography coupled with ESI-MS identified a large number of degradation products in very small quantities for the same dose. The cation radicals were formed by the loss of a Bu . group, the Me . group, or two H . atoms to form a double bond with the butyl chain. Radiolysis of the anion produced mainly F . and CF 3 . radicals. The anion radicals recombined with the cation to form a wide range of secondary degradation products regardless of the radiolysis conditions. (authors)

  4. Stability of [MeBu{sub 3}N][Tf{sub 2}N] under gamma irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Bosse, Emilie; Berthon, Laurence; Zorz, Nicole; Monget, Julie; Berthon, Claude; Bisel, Isabelle; Legand, Solene; Moisy, Philippe [CEA Marcoule, DCRP/SCPS, BP 17171, 30207 Bagnols sur Ceze Cedex (France)

    2008-07-01

    The stability of the ionic liquid [MeBu{sub 3}N][Tf{sub 2}N], dry or after contact with water (where [MeBu{sub 3}N]{sup +} is the methyl-tributyl-ammonium cation and [Tf{sub 2}N]{sup -} is the bistriflimide anion), was studied under {sup 137}Cs gamma irradiation in argon and in air. In a quantitative study with an absorbed dose of 2 MGy this ionic liquid was highly stable regardless of the radiolysis conditions. The radiolytic disappearance yields determined by ESI-MS were -0.38 and -0.25 {mu}mol*J{sup -1} for the cation and anion, respectively. ESI-MS, NMR, and liquid chromatography coupled with ESI-MS identified a large number of degradation products in very small quantities for the same dose. The cation radicals were formed by the loss of a Bu{sup .} group, the Me{sup .} group, or two H{sup .} atoms to form a double bond with the butyl chain. Radiolysis of the anion produced mainly F{sup .} and CF{sub 3}{sup .} radicals. The anion radicals recombined with the cation to form a wide range of secondary degradation products regardless of the radiolysis conditions. (authors)

  5. Stability of [MeBu3N][Tf2N] under gamma irradiation

    International Nuclear Information System (INIS)

    Bosse, E.; Berthon, L.; Zorz, N.; Monget, J.; Berthon, C.; Bisel, I.; Legand, S.; Moisy, P.

    2008-01-01

    The stability of the ionic liquid [MeBu 3 N][Tf 2 N], dry or after contact with water (where [MeBu 3 N] + is the methyl-tributyl-ammonium cation and [Tf 2 N] - is the bistriflimide anion), was studied under 137 Cs gamma irradiation in argon and in air. In a quantitative study with an absorbed dose of 2 MGy this ionic liquid was highly stable regardless of the radiolysis conditions. The radiolytic disappearance yields determined by ESI-MS were -0.38 and -0.25 μmolJ -1 for the cation and anion, respectively. ESI-MS, NMR, and liquid chromatography coupled with ESI-MS identified a large number of degradation products in very small quantities for the same dose. The cation radicals were formed by the loss of a Bu-radical group, the Me-radical group, or two H-radical atoms to form a double bond with the butyl chain. Radiolysis of the anion produced mainly F-radical and CF 3 -radicals. The anion radicals recombined with the cation to form a wide range of secondary degradation products regardless of the radiolysis conditions. (authors)

  6. Analysis and tests of TF magnet insulation samples for the JET upgrade to 4 tesla

    CERN Document Server

    Miele, P; Bettinali, L; Kaye, A; Last, J; Papastergiou, S; Riccardo, V; Visca, E

    2000-01-01

    The JET Toroidal Field (TF) coils were originally designed for operation at 3.4 tesla. In order to upgrade the field to 4 tesla and thus improve the performance of the JET machine, new mechanical tests and analysis were carried out on the insulation of TF coil samples. They are aimed at investigating the mechanical properties and the status of the insulation in order to set allowable stresses and force limits. In particular since the shear stress in the insulation is strongly affected by the shear modulus of elasticity G, it is important to measure this parameter. A method for the measurement of G in glass-resin fibres, the V-notched beam method (Iosipescu method) , was applied. The particular shape of the rectangular Iosipescu V- notched sample and the particular modality of force application produce pure shear stress for a reliable measurement of the G value and of the shear strength of the insulation. The effect of temperature on these mechanical properties was also investigated. Results show higher averag...

  7. Detailed design studies at CEA for JT-60SA TF coils

    International Nuclear Information System (INIS)

    Decool, P.; Marechal, J.L.; Portafaix, C.; Lacroix, B.; Gros, G.; Verger, J.M.

    2011-01-01

    Following a first conceptual design activity in which the general design of the JT-60SA TF system was defined and frozen in agreement with all the participants in the project (CEA, ENEA, F4E), a second phase had to be launched to deal with the detailed design. In this paper, we present the work performed at CEA on the TF coil design during this second phase. Part of this work, concerns the determination of conductor hydraulic performances during operation as well as in factory. The thermohydraulic of the conductor was also assessed to confirm the need of helium inlets and a specific design was developed and qualified to be compatible with the available hydraulic performance of the cryoplant. The mechanical behavior is still to be assessed and qualified. Last but not least, the inner electrical joints of the coil have been modified with respect to the original twin-box design developed by CEA for the ITER coils in order to simplify the fabrication process. A dedicated qualification program for their manufacture is ongoing.

  8. TFTR D and D Project: Final Examination and Testing of the TFTR TF-Coils

    International Nuclear Information System (INIS)

    Zatz, Irving J.

    2003-01-01

    In operation for nearly 15 years, TFTR (Tokamak Fusion Test Reactor) was not only a fusion science milestone, but a milestone of achievement in engineering as well. The TFTR DandD (Decommissioning and Decontamination) program provided a rare opportunity to examine machine components that had been exposed to a unique performance environment of greater than 100,000 mechanical and thermal load cycles. In particular, the possible examination of the TFTR toroidal-field (TF) coils, which met, then exceeded, the 5.2 Tesla magnetic field machine specification, could supply the answers to many questions that have been asked and debated since the coils were originally designed and built. A test program conducted in parallel with the DandD effort was the chance to look inside and examine, in detail, the TFTR TF coils for the first time since they were delivered encased to PPPL (Princeton Plasma Physics Laboratory). The results from such a program would provide data and insight that would not only be nefit PPPL and the fusion community, but the broader scientific community as well

  9. Δim-lacunary statistical convergence of order α

    Science.gov (United States)

    Altınok, Hıfsı; Et, Mikail; Işık, Mahmut

    2018-01-01

    The purpose of this work is to introduce the concepts of Δim-lacunary statistical convergence of order α and lacunary strongly (Δim,p )-convergence of order α. We establish some connections between lacunary strongly (Δim,p )-convergence of order α and Δim-lacunary statistical convergence of order α. It is shown that if a sequence is lacunary strongly (Δim,p )-summable of order α then it is Δim-lacunary statistically convergent of order α.

  10. Radiological information management system (RadIMS)

    International Nuclear Information System (INIS)

    Oesterling, R.G.; Marko, S.A.; Tschaeche, A.N.

    1991-01-01

    Westinghouse Idaho Nuclear Company, Inc. (WINCO) is developing and implementing an information management system, known as RadIMS, to track and record personnel exposure to ionizing radiation. RadIMS has been designed to fulfill all the requirements of US Department of Energy (USDOE) Order 5480.11, ''Radiation Protection for Occupational Workers.'' This Order requires the contractor to maintain detailed radiation exposure records on all individuals who work at the facility. These records must be retrievable for the entire working life of the individual and be available to other USDOE contractors on request. To meet these general needs, RadIMS provides for retrieval of detailed, comprehensive individual exposure histories as well as the usual online interactions to accomplish day-today radiation protection operations. These two extremes of functionality require different approaches in the WINCO computing environment. The exposure histories include database text, paper, microfilm, and electronic bitmaps

  11. Radiological information management system (RadIMS)

    Energy Technology Data Exchange (ETDEWEB)

    Oesterling, R.G.; Marko, S.A.; Tschaeche, A.N.

    1991-08-19

    Westinghouse Idaho Nuclear Company, Inc. (WINCO) is developing and implementing an information management system, known as RadIMS, to track and record personnel exposure to ionizing radiation. RadIMS has been designed to fulfill all the requirements of US Department of Energy (USDOE) Order 5480.11, Radiation Protection for Occupational Workers.'' This Order requires the contractor to maintain detailed radiation exposure records on all individuals who work at the facility. These records must be retrievable for the entire working life of the individual and be available to other USDOE contractors on request. To meet these general needs, RadIMS provides for retrieval of detailed, comprehensive individual exposure histories as well as the usual online interactions to accomplish day-today radiation protection operations. These two extremes of functionality require different approaches in the WINCO computing environment. The exposure histories include database text, paper, microfilm, and electronic bitmaps.

  12. Radiological information management system (RadIMS)

    Energy Technology Data Exchange (ETDEWEB)

    Oesterling, R.G.; Marko, S.A.; Tschaeche, A.N.

    1991-08-19

    Westinghouse Idaho Nuclear Company, Inc. (WINCO) is developing and implementing an information management system, known as RadIMS, to track and record personnel exposure to ionizing radiation. RadIMS has been designed to fulfill all the requirements of US Department of Energy (USDOE) Order 5480.11, ``Radiation Protection for Occupational Workers.`` This Order requires the contractor to maintain detailed radiation exposure records on all individuals who work at the facility. These records must be retrievable for the entire working life of the individual and be available to other USDOE contractors on request. To meet these general needs, RadIMS provides for retrieval of detailed, comprehensive individual exposure histories as well as the usual online interactions to accomplish day-today radiation protection operations. These two extremes of functionality require different approaches in the WINCO computing environment. The exposure histories include database text, paper, microfilm, and electronic bitmaps.

  13. Midlatitude magnetometer chains during the IMS

    International Nuclear Information System (INIS)

    Mcpherron, R.L.

    1982-01-01

    The International Magnetospheric Study (IMS) is an international program to study global problems of magnetospheric dynamics. A key element of the U.S. participation in this program was the establishment of a ground magnetometer network. This network included a number of arrays at high and low latitudes. This report describes three chains established at midlatitudes, including the IMS Midlatitude Chain, the AFGL Magnetometer Network, and the Bell Lab Conjugate Array. Descriptions of the type of equipment, station locations, types of data display, and availability of data for each chain are presented in this report. A major problem of the data analysis phase of the IMS will be reducing selected subsets of these data to a common format. Currently, there are no plans to do this in a systematic manner

  14. AC loss, interstrand resistance and mechanical properties of prototype EU DEMO TF conductors up to 30 000 load cycles

    Science.gov (United States)

    Yagotintsev, K.; Nijhuis, A.

    2018-07-01

    Two prototype Nb3Sn cable-in-conduit conductors conductors were designed and manufactured for the toroidal field (TF) magnet system of the envisaged European DEMO fusion reactor. The AC loss, contact resistance and mechanical properties of two sample conductors were tested in the Twente Cryogenic Cable Press under cyclic load up to 30 000 cycles. Though both conductors were designed to operate at 82 kA in a background magnetic field of 13.6 T, they reflect different approaches with respect to the magnet winding pack assembly. The first approach is based on react and wind technology while the second is the more common wind and react technology. Each conductor was tested first for AC loss in virgin condition without handling. The impact of Lorentz load during magnet operation was simulated using the cable press. In the press each conductor specimen was subjected to transverse cyclic load up to 30 000 cycles in liquid helium bath at 4.2 K. Here a summary of results for AC loss, contact resistance, conductor deformation, mechanical heat production and conductor stiffness evolution during cycling of the load is presented. Both conductors showed similar mechanical behaviour but quite different AC loss. In comparison with previously tested ITER TF conductors, both DEMO TF conductors possess very low contact resistance resulting in high coupling loss. At the same time, load cycling has limited impact on properties of DEMO TF conductors in comparison with ITER TF conductors.

  15. Developing an effective IM/IT strategy.

    Science.gov (United States)

    Kramer, Sarah; Walker, Joanne; Falk, Will

    2009-01-01

    Healthcare organizations and systems around the world lag far behind banking, manufacturing, travel and other industries in their use of information management/information technology (IM/IT) to deliver high-quality products and services. Across Canada, healthcare organizations, as well as governments, understand that information and information technology are needed to deliver quality care and to sustain our publicly funded health system. However, insufficient funding, few experienced resources, lack of strong leadership and absence of clear business/clinical rationale have restricted innovation and advancement in the use of IM/IT to improve healthcare delivery and patient outcomes.

  16. Application of [HMim][NTf2], [HMim][TfO] and [BMim][TfO] ionic liquids on the extraction of toluene from alkanes: Effect of the anion and the alkyl chain length of the cation on the LLE

    International Nuclear Information System (INIS)

    Corderí, Sandra; González, Emilio J.; Calvar, Noelia; Domínguez, Ángeles

    2012-01-01

    Highlights: ► Several ionic liquids were studied as solvent to extract toluene from heptane and cyclohexane. ► (Liquid + liquid) equilibrium data were measured at 298.15 K and atmospheric pressure. ► Selectivity and solute distribution ratio were calculated and compared with those found in literature for sulfolane. ► Experimental data were correlated using NRTL and UNIQUAC thermodynamic models. - Abstract: In this paper, the separation of toluene from the aliphatic hydrocarbons heptane and cyclohexane employing the ionic liquids 1-hexyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, [HMim][NTf 2 ], 1-hexyl-3-methylimidazolium trifluoromethanesulfonate, [HMim][TfO] and 1-butyl-3-methylimidazolium trifluoromethanesulfonate, [BMim][TfO], as solvents was studied and discussed. Liquid–liquid equilibrium data for the ternary systems {heptane, or cyclohexane + toluene + [HMim][NTf 2 ], or [HMim][TfO], or [BMim][TfO]} and {heptane + cyclohexane + [HMim][NTf 2 ], or [HMim][TfO], or [BMim][TfO]} were measured at T = 298.15 K and atmospheric pressure. The degree of consistency of the tie-lines was tested using the Othmer–Tobias equation. The solute distribution ratio and selectivity, derived from the experimental tie-lines, were used to determine if these ionic liquids can be used as potential solvents on the extraction of toluene from aliphatic hydrocarbons; a comparison with literature data where sulfolane is used as solvent was also included. Finally, the experimental data were correlated with the NRTL and UNIQUAC thermodynamic models.

  17. EU ITER TF coil: Dimensional metrology, a key player in the Double Pancake integration

    International Nuclear Information System (INIS)

    Poncet, L.; Bellesia, B.; Oliva, A. Bonito; Boter Rebollo, E.; Cornelis, M.; Cornella Medrano, J.; Harrison, R.; Bue, A. Lo; Moreno, A.; Foussat, A.; Felipe, A.; Echeandia, A.; Barutti, A.; Caserza, B.; Barbero, P.; Stenca, S.; Da Re, A.; Silva Ribeiro, J.; Brocot, C.; Benaoun, S.

    2015-01-01

    Highlights: • Development and qualification of a dimensional metrology procedure on wound superconductor trajectory based on Laser scanning system. • Dimensional control of the conductor centreline during winding, before and after heat treatment. • Radial Plate groove centreline length controlled using Laser Trackers. • Full scale wound Double Pancake prototype transferred inside Radial Plate prototype without any issues. - Abstract: The ITER Toroidal Field (TF) magnet system consists of 18 “D” shaped coils. Fusion for Energy (F4E), the European Domestic Agency for ITER, is responsible for the supply of 10 out the 19 TF coils (18 installed plus one spare coil). Each TF coil, about 300 t in weight, is made of a stainless steel case containing a Winding Pack (WP). The European manufacturing of the Radial Plates (RPs) and WPs has been awarded to two different industrial partners, whose activities are strongly linked with each other. In order to manufacture a Double Pancake (DP), first, the conductor has to be bent onto a D-shaped double spiral trajectory, then heat treated and inserted in the grooves of the RP. This represents the most challenging manufacturing step: in order to fit inside the groove, the double spiral trajectory of the conductor must match almost perfectly the trajectory of the groove, over a length above 700 m. In order to achieve this, the conductor trajectory length must be controlled with an accuracy of 1 mm over a length of 350 m while the radial plate groove has to be machined with tolerances of ±0.2 mm over dimensions of more than 10 m. In order to succeed, it has been essential to develop a metrology process capable to control with high accuracy both the DP conductor and the RP groove trajectories. This paper reports on the work carried out on the development and qualification of the dimensional metrology to monitor the manufacturing of the conductor. Reference is made to the final dimensional check of the RP focusing on the

  18. Electromagnetic and structural global model of the TF magnet system in ASDEX Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Zammuto, I., E-mail: irene.zammuto@ipp.mpg.de [Max-Planck-Institut für Plasmaphysik, EURATOM Association, D-85740 Garching (Germany); Streibl, B.; Giannone, L.; Herrmann, A.; Kallenbach, A.; Mertens, V. [Max-Planck-Institut für Plasmaphysik, EURATOM Association, D-85740 Garching (Germany)

    2013-10-15

    Highlights: ► An electromagnetic and structural FE 3D model is set up for ASDEX Upgrade. ► The model is benchmarked against the old design results, present displacement measurements. ► The benchmarked model is applied to the present plasma configurations, which have a different poloidal field distribution with respect to the design case. ► The different poloidal field influences the out-of-plane force distribution, thus requiring an update of the TF safety system. -- Abstract: The enhancements carried out in the tokamak ASDEX Upgrade (AUG) are oriented toward the preparation of the future physics-related activities of ITER and DEMO. To address the main ITER issues, plasma configurations with a wider operational limit (e.g. higher triangularity) are planned for the future experimental campaigns in AUG. To evaluate the mechanical impact on the toroidal field (TF) magnet system a combined electromagnetic and structural finite element model was set up. At first extensive benchmarks of the models are carried out against the AUG reference design configurations with respect to stress [1–3], lateral displacement measurements and poloidal flux pattern. The numerical model was then applied to a set of actual high triangularity (HT) configurations generated by a more favorable poloidal field (PF) current distribution made possible by an extension of the power supply system. The resulting change of the poloidal flux pattern and the lateral force distribution has consequences for the coil shear stress and vault stability. Both aspects are monitored by a safety system measuring the PF flux placed on top and bottom of the outer surface of two TF coils (TFCs) between vault and the TFC supporting structure, so called Turn Over Structure (TOS). The range of the new HT configurations has induced a modification of the flux pattern, so that an adaptation of safety system is required to protect the TFCs system. Following the same criteria of the old safety system [4,5], a new

  19. Identifying Cancer Subtypes from miRNA-TF-mRNA Regulatory Networks and Expression Data.

    Directory of Open Access Journals (Sweden)

    Taosheng Xu

    Full Text Available Identifying cancer subtypes is an important component of the personalised medicine framework. An increasing number of computational methods have been developed to identify cancer subtypes. However, existing methods rarely use information from gene regulatory networks to facilitate the subtype identification. It is widely accepted that gene regulatory networks play crucial roles in understanding the mechanisms of diseases. Different cancer subtypes are likely caused by different regulatory mechanisms. Therefore, there are great opportunities for developing methods that can utilise network information in identifying cancer subtypes.In this paper, we propose a method, weighted similarity network fusion (WSNF, to utilise the information in the complex miRNA-TF-mRNA regulatory network in identifying cancer subtypes. We firstly build the regulatory network where the nodes represent the features, i.e. the microRNAs (miRNAs, transcription factors (TFs and messenger RNAs (mRNAs and the edges indicate the interactions between the features. The interactions are retrieved from various interatomic databases. We then use the network information and the expression data of the miRNAs, TFs and mRNAs to calculate the weight of the features, representing the level of importance of the features. The feature weight is then integrated into a network fusion approach to cluster the samples (patients and thus to identify cancer subtypes. We applied our method to the TCGA breast invasive carcinoma (BRCA and glioblastoma multiforme (GBM datasets. The experimental results show that WSNF performs better than the other commonly used computational methods, and the information from miRNA-TF-mRNA regulatory network contributes to the performance improvement. The WSNF method successfully identified five breast cancer subtypes and three GBM subtypes which show significantly different survival patterns. We observed that the expression patterns of the features in some miRNA-TF

  20. Redesigning pH optimum of Geobacillus sp. TF16 endoxylanase through in silico designed DNA swapping strategy.

    Science.gov (United States)

    Uzuner, Ugur; Canakci, Sabriye; Bektas, Kadriye Inan; Sapmaz, Merve Tuncel; Belduz, Ali Osman

    2017-06-01

    Thermoalkaliphilic xylanases are highly desired and of great importance due to their vast potential in paper pulp and bleaching processes. Here, we report rapid, cost-effective, and result-oriented combinatorial potential of in silico DNA swapping strategy to engineer the pH optimum of industrially crucial enzymes, particularly engineering of Geobacillus sp. TF16 endoxylanase for alkaline environments. The 3D structures of Geobacillus sp. TF16 and donor Bacillus halodurans C-125 endoxylanases were firstly predicted, analyzed, and compared for their similarities before any in silico design of mutants. Reasonably, to improve its alkaline pH tolerance, the corresponding regions in Geobacillus sp.TF16 endoxylanase were further engineered by swapping with negatively-charged amino acid-rich regions from B. halodurans C-125 endoxylanase. Through only two of four in silico-designed mutants, the optimum pH of GeoTF16 endoxylanase was improved from 8.5 to 10.0. Moreover, as compared to GeoTF16 parental enzyme, both GeoInt3 and GeoInt4 mutants revealed (i) enhanced biobleaching performance, (ii) improved adaptability to alkaline conditions, and (iii) better activity for broader pH range. Unlike GeoTF16 losing activity at pH 11.0 completely, GeoInt4 retained 60% and 40% of its activity at pH 11.0 and 12.0, respectively. Thus, GeoInt4 stands out as a more competent biocatalyst that is suitable for alkaline environments of diverse industrial applications. The current study represents an efficient protein engineering strategy to adapt industrial catalysts to diverse processing conditions. Further comprehensive and fine-tuned research efforts may result in biotechnologically more promising outcomes. Copyright © 2017 Elsevier B.V. and Société Française de Biochimie et Biologie Moléculaire (SFBBM). All rights reserved.

  1. GENIUS-TF - a test facility for the GENIUS project. Proposal

    International Nuclear Information System (INIS)

    Klapdor-Kleingrothaus, H.V.; Dietz, A.; Heusser, G.

    2001-02-01

    GENIUS is a proposal for a large scale detector of rare events. As a first step of the experiment, a small test version, the Genius Test-Facility is proposed to be built up at the Laboratori Nazionali del Gran Sasso (LNGS). With about 40 kg of natural Ge detectors operated in liquid nitrogen, Genius-TF could exclude (or directly confirm) the DAMA annual modulation signature within about two years of measurement using both, signal and signature of the claimed WIMP Dark matter. The funding of the experiment has already been approved and four 2.5 kg germanium detectors with an extreme low treshold of 500 eV have been produced. The installation can be started immediately. No additional space in the Underground Laboratory is required. (orig.)

  2. Asymmetry of edge plasma turbulence in biasing experiments on tokamak TF-2

    International Nuclear Information System (INIS)

    Budaev, V.P.

    1994-01-01

    It was observed in tokamaks the suppression of edge turbulence causes by setting a radial electric field at the plasma edge. The poloidal plasma rotation governed by this electric field is likely to result in changes in edge convention and poloidal asymmetry, however there is no experimental evidence about that of the experimental database concerning the biasing and conditions of edge plasma electrostatic turbulence excitation is not still complete. Also a relation between macroscopic convection and small-scale electrostatic turbulence have not yet revealed both in biasing and non biasing plasmas. In this paper results from biasing experiments carried on on ohmically heated tokamak TF-2 are presented. Changes in both equilibrium and fluctuated edge plasma parameters also convection and turbulence driven particle flux were demonstrated in probe measurements with biasing of electrode immersed within Last Closed Flux Surface (LCFS). Poloidal edge plasma structure and charge in asymmetry have demonstrated in the biasing experiments. (author). 6 refs, 4 figs

  3. A coil test facility for the cryogenic tests of the JT-60SA TF coils

    International Nuclear Information System (INIS)

    Chantant, M.; Genini, L.; Bayetti, P.; Millet, F.; Wanner, M.; Massaut, V.; Corte, A. Della; Ardelier-Desage, F.; Catherine-Dumont, V.; Dael, A.; Decool, P.; Donati, A.; Duchateau, J.L.; Garibaldi, P.; Girard, S.; Hatchressian, J.C.; Fejoz, P.; Jamotton, P.; Jourdheuil, L.; Juster, F.P.

    2011-01-01

    In the framework of the Broader Approach Activities, the EU will deliver to Japan the 18 superconducting coils, which constitute the JT-60SA Toroidal field magnet. These 18 coils, manufactured by France and Italy, will be cold tested before shipping to Japan. For this purpose, the European Joint Undertaking for ITER, the Development of Fusion Energy ('Fusion for Energy', F4E) and the European Voluntary Contributors are collaborating to design and set-up a coil test facility (CTF) and to perform the acceptance test of the 18 JT-60SA Toroidal Field (TF) coils. The test facility is designed to test one coil at a time at nominal current and cryogenic temperature. The test of the first coil of each manufacturer includes a quench triggered by increasing the temperature. The project is presently in the detailed design phase.

  4. Improving the computation efficiency of COBRA-TF for LWR safety analysis of large problems

    International Nuclear Information System (INIS)

    Cuervo, D.; Avramova, M. N.; Ivanov, K. N.

    2004-01-01

    A matrix solver is implemented in COBRA-TF in order to improve the computation efficiency of both numerical solution methods existing in the code, the Gauss elimination and the Gauss-Seidel iterative technique. Both methods are used to solve the system of pressure linear equations and relay on the solution of large sparse matrices. The introduced solver accelerates the solution of these matrices in cases of large number of cells. The execution time is reduced in half as compared to the execution time without using matrix solver for the cases with large matrices. The achieved improvement and the planned future work in this direction are important for performing efficient LWR safety analyses of large problems. (authors)

  5. Thermal-hydraulic analysis of LTS cables for the DEMO TF coil using simplified models

    Directory of Open Access Journals (Sweden)

    Lewandowska Monika

    2017-03-01

    Full Text Available The conceptual design activities for the DEMOnstration reactor (DEMO – the prototype fusion power plant – are conducted in Europe by the EUROfusion Consortium. In 2015, three design concepts of the DEMO toroidal field (TF coil were proposed by Swiss Plasma Center (EPFL-SPC, PSI Villigen, Italian National Agency for New Technologies (ENEA Frascati, and Atomic Energy and Alternative Energies Commission (CEA Cadarache. The proposed conductor designs were subjected to complete mechanical, electromagnetic, and thermal-hydraulic analyses. The present study is focused on the thermal-hydraulic analysis of the candidate conductor designs using simplified models. It includes (a hydraulic analysis, (b heat removal analysis, and (c assessment of the maximum temperature and the maximum pressure in each conductor during quench. The performed analysis, aimed at verification whether the proposed design concepts fulfil the established acceptance criteria, provides the information for further improvements of the coil and conductors design.

  6. Quickly Planning TF/TA2 Trajectory by Artificial Immune Algorithm

    Directory of Open Access Journals (Sweden)

    LIU Lifeng

    2015-04-01

    Full Text Available Flight path planning by artificial immune algorithm approach met the requirements of aircraft's flyability and operation is proposed for the problem of single and double TF/TA2 flight path planning. Punishment function (affinity function with comprehensive 3D threat information is designed. A comprehensive threat model is formed including dynamic and static threats and no-fly-zone. Accordingly, single and dual flight paths are planned by AIA, which have been compared with the paths by GA. The results show that, GA's planned a quick and longer path compared under simple threat environment; in complex environments, GA has high failure rate (greater than 95% for single aircraft, but it is failed for double aircrafts. For the single and double aircrafts, AIA can provides one optimal and more candidate optimal flight paths.

  7. Room Temperature Magnetic Determination of the Current Center Line for the ITER TF Coils

    CERN Document Server

    Lerch, Philippe; Buzio, Marco; Negrazus, Marco; Baynham, Elwyn; Sanfilippo, Stephane; Foussat, Arnaud

    2014-01-01

    The ITER tokamak includes 18 superconducting D-shaped toroidal field (IT) coils. Unavoidable shape deformations as well as assembly errors will lead to field errors, which can be modeled with the knowledge of the current center line (CCL). Accurate survey during the entire manufacturing and assembly process, including transfer of survey points, is complex. In order to increase the level of confidence, a room temperature magnetic measurement of the CCL on assembled and closed winding packs is foreseen, prior to insertion into their cold case. In this contribution, we discuss the principle of the CCL determination and present a low frequency ac measurement system under development at PSI, within an ITER framework contract. The largest current allowed to flow in the TF coil at room temperature and the precision requirements for the determination of the CCL loci of the coil are hard boundaries. Eddy currents in the radial plates, the winding pack enclosures, and possibly from iron in the reinforced concrete floor...

  8. BOREAS TF-3 Automated Chamber CO2 Flux Data from the NSA-OBS

    Science.gov (United States)

    Goulden, Michael L.; Crill, Patrick M.; Hall, Forrest G. (Editor); Conrad, Sara (Editor)

    2000-01-01

    The BOReal Ecosystem Atmosphere Study Tower Flux (BOREAS TF-3) and Trace Gas Biogeochemistry (TGB-1) teams collected automated CO2 chamber flux data in their efforts to fully describe the CO2 flux at the Northern Study Area-Old Black Spruce (NSA-OBS) site. This data set contains fluxes of CO2 at the NSA-OBS site measured using automated chambers. In addition to reporting the CO2 flux, it reports chamber air temperature, moss temperature, and light levels during each measurement. The data set covers the period from 23-Sep-1995 through 26-Oct-1995 and from 28-May-1996 through 21-Oct-1996. The data are stored in tabular ASCII files.

  9. Systeme im Einsatz. Lernmanagement, Kompetenzmanagement und PLE

    NARCIS (Netherlands)

    Kalz, Marco; Schön, Sandra; Lindner, Martin; Roth, Detlev; Baumgartner, Peter

    2011-01-01

    Kalz, M., Schön, S., Lindner, M., Roth, D., & Baumgartner, P. (2011). Systeme im Einsatz. Lernmanagement, Kompetenzmanagement und PLE. In M. Ebner, & S. Schön (Eds.), L3T - Lerhbuch für Lernen und Lehren mit Technologie (pp. 111-118). Graz, Austria: Uni Graz. Available at

  10. IMS Learning Design: De stand van zaken

    NARCIS (Netherlands)

    Tattersall, Colin; Manderveld, Jocelyn

    2005-01-01

    Tattersall, C. & Manderveld, J. (2004) IMS Learning Design: De stand van zaken In: Gorissen, P., Manderveld, J., Benneker, F. & Cordewener, B. Leertechnologie in de Lage Landen (pp. 31-33). Utrecht, Stichting Surf. Ook beschikbaar in dspace: http://hdl.handle.net/1820/270

  11. An IMS testbed for SIP applications

    DEFF Research Database (Denmark)

    Caba, Cosmin Marius; Soler, José

    2013-01-01

    The paper presents the design and implementation of an emulation platform for the IP Multimedia Subsystem. The SIP Servlet API v1.1 has been used to implement the final system. The purpose of the emulation is to offer to IMS service developers an environment where they can integrate development...

  12. Quench propagation and quench detection in the TF system of JT-60SA

    International Nuclear Information System (INIS)

    Lacroix, Benoit; Duchateau, Jean-Luc; Meuris, Chantal; Ciazynski, Daniel; Nicollet, Sylvie; Zani, Louis; Polli, Gian-Mario

    2013-01-01

    Highlights: • The JT-60SA primary quench detection system will be based on voltage measurements. • The early quench propagation was studied in the JT-60SA TF conductor. • The impact of the conductor jacket on the hot spot criterion was quantified. • The detection parameters were investigated for different quench initiations. -- Abstract: In the framework of the JT-60SA project, France and Italy will provide to JAEA 18 Toroidal Field (TF) coils including NbTi cable-in-conduit conductors. During the tokamak operation, these coils could experience a quench, an incidental event corresponding to the irreversible transition from superconducting state to normal resistive state. Starting from a localized disturbance, the normal zone propagates along the conductor and dissipates a large energy due to Joule heating, which can cause irreversible damages. The detection has to be fast enough (a few seconds) to trigger the current discharge, so as to dump the stored magnetic energy into an external resistor. The JT-60SA primary quench detection system will be based on voltage measurements, which are the most rapid technology. The features of the detection system must be adjusted so as to detect the most probable quenches, while avoiding inopportune fast safety discharges. This requires a reliable simulation of the early quench propagation, performed in this study with the Gandalf code. The conductor temperature reached during the current discharge must be kept under a maximal value, according to the hot spot criterion. In the present study, a hot spot criterion temperature of 150 K was taken into account and the role of each conductor component (strands, helium and conduit) was analyzed. The detection parameters were then investigated for different hypotheses regarding the quench initiation

  13. Uji Unjuk Kerja Traktor Yanmar Tipe TF 85 pada Lahan Basah dan Lahan Kering di Desa Dolok Hataran, Kabupaten Simalungun

    OpenAIRE

    Tobing, Toman Harry Duga L.

    2010-01-01

    TOMAN H D L. TOBING: Performance of Yanmar TF 85 Tractor on Wet land and Dry land at Desa Dolok Hataran Kabupaten Simalungun. Under the supervision of TAUFIK RIZALDI and AINUN ROHANAH. The performance test of tractor is its ability to prepare land using implements to know the work capacity, efficiency, work velocity, and wheel skid. The objective of this research is to know the capacity of Yanmar TF 85 tractor on wet land and dry land at Desa Dolok Hataran Kabupaten Simalungun. This rese...

  14. Managing P2P services via the IMS

    NARCIS (Netherlands)

    Liotta, A.; Lin, L.

    2007-01-01

    The key aim of our work was to illustrate the benefits and means to deploy P2P services via the IMS. Having demonstrated the technical viability of P2P-IMS we have also found a way to add a new management dimension to existing P2P systems. P2P-IMS comes with a natural "data management" mechanism,

  15. [Kriegsland im Osten Eroberung, Kolonisierung und Militärherrschaft im Ersten Weltkrieg] / Markus Pöhlmann

    Index Scriptorium Estoniae

    Pöhlmann, Markus

    2003-01-01

    Rets.: Vejas Gabriel Liulevicius. Kriegsland im Osten Eroberung, Kolonisierung und Militärherrschaft im Ersten Weltkrieg. Aus dem Amerikanischen von Jürgen Bauer, Edith Nerke und Fee Engemann. Hamburg : 2002

  16. The Application of Internal Marketing (IM in a Service Organization

    Directory of Open Access Journals (Sweden)

    R. Sharma

    2013-07-01

    Findings and Strategic Implications. To complement earlier theoretical proposition on IM, the findings indicate that there are several empirical aspects such as “costs, people and concept” which hinder successful implementation of IM. This study proposes several strategic HR recommendations to reduce the “implementation gap” in IM such as to conduct continuous staff training on IM knowledge on regular time intervals, to reduce excessive work load and pressure and engaging staff members in continuous personal development sessions. In addition, the findings reveal that IM training should be given priority to solve “people-oriented” issues.

  17. Impact of sodium butyrate and mild hypothermia on metabolic and physiological behaviour of CHO TF 70R cells

    Directory of Open Access Journals (Sweden)

    Veronica Avello

    2017-05-01

    Conclusions: The combination of NaBu addition and mild hypothermic condition causes an impact on physiological and metabolic state of CHO TF 70R cells, decreasing cell growth rate and improving glucose consumption efficiency. These results therefore provide a promising strategy to increase specific productivity of rh-tPA.

  18. Urokinase-type plasminogen activator receptor (uPAR), tissue factor (TF) and epidermal growth factor receptor (EGFR)

    DEFF Research Database (Denmark)

    Christensen, Anders; Kiss, Katalin; Lelkaitis, Giedrius

    2017-01-01

    Background: Tumor-specific biomarkers are a prerequisite for the development of targeted imaging and therapy in oral squamous cell carcinoma (OSCC). urokinase-type Plasminogen Activator Receptor (uPAR), Tissue Factor (TF) and Epidermal Growth Factor Receptor (EGFR) are three biomarkers that exhib...... with a reduced survival. uPAR seems to be a prognostic biomarker in oral cancer....

  19. APT Blanket Detailed Bin Model Based on Initial Plate-Type Design -3D FLOWTRAN-TF Model

    International Nuclear Information System (INIS)

    Hamm, L.L.

    1998-01-01

    This report provides background information for a series of reports documenting accident scenario simulations for the Accelerator Production of Tritium (APT) blanket heat removal systems. The simulations were performed in support of the Preliminary Safety Analysis Report for the APT. This report gives a brief description of the FLOWTRAN-TF code which was used for detailed blanket bin modeling

  20. λ (Δim) -statistical convergence of order α

    Science.gov (United States)

    Colak, Rifat; Et, Mikail; Altin, Yavuz

    2017-09-01

    In this study, using the generalized difference operator Δim and a sequence λ = (λn) which is a non-decreasing sequence of positive numbers tending to ∞ such that λn+1 ≤ λn+1, λ1 = 1, we introduce the concepts of λ (Δim) -statistical convergence of order α (α ∈ (0, 1]) and strong λ (Δim) -Cesàro summablility of order α (α > 0). We establish some connections between λ (Δim) -statistical convergence of order α and strong λ (Δim) -Cesàro summablility of order α. It is shown that if a sequence is strongly λ (Δim) -Cesàro summable of order α, then it is λ (Δim) -statistically convergent of order β in case 0 < α ≤ β ≤ 1.

  1. Tea polyphenols EGCG and TF restrict tongue and liver carcinogenesis simultaneously induced by N-nitrosodiethylamine in mice

    Energy Technology Data Exchange (ETDEWEB)

    Sur, Subhayan, E-mail: subhayansur18@gmail.com [Dept. of Oncogene Regulation, Chittaranjan National Cancer Institute, 37, S.P. Mukherjee Road, Kolkata 700 026, West Bengal (India); Pal, Debolina; Roy, Rituparna; Barua, Atish [Dept. of Oncogene Regulation, Chittaranjan National Cancer Institute, 37, S.P. Mukherjee Road, Kolkata 700 026, West Bengal (India); Roy, Anup [North Bengal Medical College and Hospital, West Bengal (India); Saha, Prosenjit [Dept. of Oncogene Regulation, Chittaranjan National Cancer Institute, 37, S.P. Mukherjee Road, Kolkata 700 026, West Bengal (India); Panda, Chinmay Kumar, E-mail: ckpanda.cnci@gmail.com [Dept. of Oncogene Regulation, Chittaranjan National Cancer Institute, 37, S.P. Mukherjee Road, Kolkata 700 026, West Bengal (India)

    2016-06-01

    The aim of this study is to understand the molecular mechanisms of N-nitrosodiethylamine (NDEA) induced multi-organ carcinogenesis in tongue and liver of the same mouse and restriction of carcinogenesis by Epigallocatechin gallate (EGCG) and Theaflavin (TF), if any. For that purpose, cellular proliferation/apoptosis, prevalence of CD44 positive stem cell population and expressions of some key regulatory genes of self renewal Wnt and Hedgehog (Hh) pathways and some of their associated genes were analyzed in the NDEA induced tongue and liver lesions in absence or presence of EGCG/TF. Chronic NDEA exposure in oral cavity could decrease mice body weights and induce tongue and liver carcinogenesis with similar histological stages (severe dysplasia up to 30th weeks of NDEA administration). Increasing mice body weights were seen in continuous and post EGCG/TF treated groups. EGCG/TF treatment could restrict both the carcinogenesis at similar histological stages showing potential chemopreventive effect in continuous treated groups (mild dysplasia) followed by pre treatment (moderate dysplasia) and therapeutic efficacy in post treated groups (mild dysplasia) up to 30th week. The mechanism of carcinogenesis by NDEA and restriction by the EGCG/TF in both tongue and liver were similar and found to be associated with modulation in cellular proliferation/apoptosis and prevalence of CD44 positive population. The up-regulation of self renewal Wnt/β-catenin, Hh/Gli1 pathways and their associated genes Cyclin D1, cMyc and EGFR along with down regulation of E-cadherin seen during the carcinogenesis processes were found to be modulated during the restriction processes by EGCG/TF. - Highlights: • Simultaneous tongue and liver carcinogenesis in mice by oral NDEA administration • Restriction of both carcinogenesis by EGCG and TF at early pre-malignant stages • The mechanisms of carcinogenesis and restriction were similar in both the organs. • Changes in proliferation

  2. Tea polyphenols EGCG and TF restrict tongue and liver carcinogenesis simultaneously induced by N-nitrosodiethylamine in mice

    International Nuclear Information System (INIS)

    Sur, Subhayan; Pal, Debolina; Roy, Rituparna; Barua, Atish; Roy, Anup; Saha, Prosenjit; Panda, Chinmay Kumar

    2016-01-01

    The aim of this study is to understand the molecular mechanisms of N-nitrosodiethylamine (NDEA) induced multi-organ carcinogenesis in tongue and liver of the same mouse and restriction of carcinogenesis by Epigallocatechin gallate (EGCG) and Theaflavin (TF), if any. For that purpose, cellular proliferation/apoptosis, prevalence of CD44 positive stem cell population and expressions of some key regulatory genes of self renewal Wnt and Hedgehog (Hh) pathways and some of their associated genes were analyzed in the NDEA induced tongue and liver lesions in absence or presence of EGCG/TF. Chronic NDEA exposure in oral cavity could decrease mice body weights and induce tongue and liver carcinogenesis with similar histological stages (severe dysplasia up to 30th weeks of NDEA administration). Increasing mice body weights were seen in continuous and post EGCG/TF treated groups. EGCG/TF treatment could restrict both the carcinogenesis at similar histological stages showing potential chemopreventive effect in continuous treated groups (mild dysplasia) followed by pre treatment (moderate dysplasia) and therapeutic efficacy in post treated groups (mild dysplasia) up to 30th week. The mechanism of carcinogenesis by NDEA and restriction by the EGCG/TF in both tongue and liver were similar and found to be associated with modulation in cellular proliferation/apoptosis and prevalence of CD44 positive population. The up-regulation of self renewal Wnt/β-catenin, Hh/Gli1 pathways and their associated genes Cyclin D1, cMyc and EGFR along with down regulation of E-cadherin seen during the carcinogenesis processes were found to be modulated during the restriction processes by EGCG/TF. - Highlights: • Simultaneous tongue and liver carcinogenesis in mice by oral NDEA administration • Restriction of both carcinogenesis by EGCG and TF at early pre-malignant stages • The mechanisms of carcinogenesis and restriction were similar in both the organs. • Changes in proliferation

  3. Pig BMSCs Transfected with Human TFPI Combat Species Incompatibility and Regulate the Human TF Pathway in Vitro and in a Rodent Model

    Directory of Open Access Journals (Sweden)

    Hongchen Ji

    2015-05-01

    Full Text Available Background: The activation of tissue factor (TF is one of the major reasons for coagulation dysregulation after pig-to-primate xenotransplantation. Tissue factor pathway inhibitor (TFPI is the most important inhibitor of TF. Studies have demonstrated species incompatibility between pig TFPI and human TF. Methods: A pig-to-macaque heterotopic auxiliary liver transplantation model was established to determine the origin of activated TF. Chimeric proteins of human and pig TFPI were constructed to assess the role of Kunitz domains in species incompatibility. Immortalised pig bone marrow mesenchymal stem cells transfected with human TFPI were tested for their ability to inhibit clotting in vitro. Results: TF from recipient was activated early after liver xenotransplantation. Pig TFPI Kunitz domain 2 bound human FXa, but Kunitz domain 1 did not effectively inhibit human TF/FVIIa. Immortalised pig bone marrow mesenchymal cells (BMSCs transfected with human TFPI showed a prolonged recalcification time in vitro and in a rodent model. Conclusion: Recipient TF is relevant to dysregulated coagulation after xenotransplantation. Kunitz domain 1 plays the most important role in species incompatibility between pig TFPI and human TF, and clotting can be inhibited by human TFPI-transfected pig BMSCs. Our study shows a possible way to resolve the incompatibility of pig TFPI.

  4. The value of Ret-Hb and sTfR in the diagnosis of iron depletion in healthy, young children

    NARCIS (Netherlands)

    Uijterschout, L.; Domellöf, M.; Vloemans, J.; Vos, R.; Hudig, C.; Bubbers, S.; Verbruggen, S.; Veldhorst, M.; de Leeuw, T.; Teunisse, P. P.; van Goudoever, J. B.; Brus, F.

    2014-01-01

    Reticulocyte hemoglobin (Ret-Hb) content and soluble transferrin receptor (sTfR) are described as promising biomarkers in the analysis of iron status. However, the value of Ret-Hb and sTfR in the early detection of iron depletion, as frequently observed in children in high-income countries, is

  5. Improved differential diagnosis of anemia of chronic disease and iron deficiency anemia: a prospective multicenter evaluation of soluble transferrin receptor and the sTfR/log ferritin index.

    Science.gov (United States)

    Skikne, Barry S; Punnonen, Kari; Caldron, Paul H; Bennett, Michael T; Rehu, Mari; Gasior, Gail H; Chamberlin, Janna S; Sullivan, Linda A; Bray, Kurtis R; Southwick, Paula C

    2011-11-01

    Anemia of chronic disease (ACD) and iron deficiency anemia (IDA) are the most prevalent forms of anemia and often occur concurrently. Standard tests of iron status used in differential diagnosis are affected by inflammation, hindering clinical interpretation. In contrast, soluble transferrin receptor (sTfR) indicates iron deficiency and is unaffected by inflammation. Objectives of this prospective multicenter clinical trial were to evaluate and compare the diagnostic accuracy of sTfR and the sTfR/log ferritin index (sTfR Index) for differential diagnosis using the automated Access(®) sTfR assay (Beckman Coulter) and sTfR Index. We consecutively enrolled 145 anemic patients with common disorders associated with IDA and ACD. Subjects with IDA or ACD + IDA had significantly higher sTfR and sTfR Index values than subjects with ACD (P < 0.0001). ROC curves produced the following cutoffs for sTfR: 21 nmol/L (or 1.55 mg/L), and the sTfR Index: 14 (using nmol/L) (or 1.03 using mg/L). The sTfR Index was superior to sTfR (AUC 0.87 vs. 0.74, P < 0.0001). Use of all three parameters in combination more than doubled the detection of IDA, from 41% (ferritin alone) to 92% (ferritin, sTfR, sTfR Index). Use of sTfR and the sTfR Index improves detection of IDA, particularly in situations where routine markers provide equivocal results. Findings demonstrate a significant advantage in the simultaneous determination of ferritin, sTfR and sTfR Index. Obtaining a ferritin level alone may delay diagnosis of combined IDA and ACD. Copyright © 2011 Wiley-Liss, Inc.

  6. Emotionsregulationsstrategien und aggressives Verhalten im Kindergartenalter

    OpenAIRE

    Helmsen, Johanna; Petermann, Franz

    2010-01-01

    In der vorliegenden Studie (N = 193) wurde untersucht, ob sich körperlich und relational aggressive Kinder im Kindergartenalter (mittleres Alter: 55 Monate) in ihren Emotionsregulationsstrategien von ihren unauffälligen Altersgenossen unterscheiden. Zur Erhebung der Emotionsregulation wurde eine strukturierte, videografierte Verhaltensbeobachtung durchgeführt, in der gezielt Frustration ausgelöst wurde. Anschließend wurden Regulationsstrategien in sieben verschiedenen Kategorien ausgewertet. ...

  7. THOR Ion Mass Spectrometer instrument - IMS

    Science.gov (United States)

    Retinò, Alessandro; Kucharek, Harald; Saito, Yoshifumi; Fraenz, Markus; Verdeil, Christophe; Leblanc, Frederic; Techer, Jean-Denis; Jeandet, Alexis; Macri, John; Gaidos, John; Granoff, Mark; Yokota, Shoichiro; Fontaine, Dominique; Berthomier, Matthieu; Delcourt, Dominique; Kistler, Lynn; Galvin, Antoniette; Kasahara, Satoshi; Kronberg, Elena

    2016-04-01

    Turbulence Heating ObserveR (THOR) is the first mission ever flown in space dedicated to plasma turbulence. Specifically, THOR will study how turbulent fluctuations at kinetic scales heat and accelerate particles in different turbulent environments within the near-Earth space. To achieve this goal, THOR payload is being designed to measure electromagnetic fields and particle distribution functions with unprecedented resolution and accuracy. Here we present the Ion Mass Spectrometer (IMS) instrument that will measure the full three-dimensional distribution functions of near-Earth main ion species (H+, He+, He++ and O+) at high time resolution (~ 150 ms for H+ , ~ 300 ms for He++) with energy resolution down to ~ 10% in the range 10 eV/q to 30 keV/q and angular resolution ~ 10°. Such high time resolution is achieved by mounting multiple sensors around the spacecraft body, in similar fashion to the MMS/FPI instrument. Each sensor combines a top-hat electrostatic analyzer with deflectors at the entrance together with a time-of-flight section to perform mass selection. IMS electronics includes a fast sweeping high voltage board that is required to make measurements at high cadence. Ion detection includes Micro Channel Plates (MCP) combined with Application-Specific Integrated Circuits (ASICs) for charge amplification, discrimination and time-to-digital conversion (TDC). IMS is being designed to address many of THOR science requirements, in particular ion heating and acceleration by turbulent fluctuations in foreshock, shock and magnetosheath regions. The IMS instrument is being designed and will be built by an international consortium of scientific institutes with main hardware contributions from France, USA, Japan and Germany.

  8. Experimentelle Untersuchungen zur sonographischen Frakturdiagnostik im Kinderalter

    OpenAIRE

    Meuser, Stefan Heinrich Peter

    2010-01-01

    Falsch diagnostiziert und nicht korrekt therapiert können Frakturen im Kindesalter zu Wachstumsstörungen und damit verbundenen lebenslangen Problemen führen. Nach einem Trauma ist die klinische Untersuchung und Bestimmung des Schmerzmaximums gerade bei Kindern oft sehr schwierig. So müssen häufig mehrere Röntgenaufnahmen getätigt werden, ehe eine Fraktur sicher diagnostiziert oder ausgeschlossen werden kann. Die hierbei auftretende ionisierende Strahlung geht jedoch besonder...

  9. Professionelle Literaturrecherche und -verwaltung im Web [Praxisbericht

    OpenAIRE

    Schaffert, Sandra

    2007-01-01

    In diesem Beitrag werden Hinweise für eine professionelle Literaturrecherche und -verwaltung im World Wide Web gegeben. Dazu werden für die pädagogische Ausbildung und Forschung einschlägige Literaturdatenbanken genannt, insbesondere solche, die kostenlos zu nutzen sind. Außerdem werden Tipps für clevere Recherchen sowie eine kurze Übersicht über Web-Werkzeuge zur Verwaltung von bibliografischen Angaben gegeben. (DIPF/Orig.)

  10. Dynamik des Kaufverhaltens im Bio-Sortiment

    OpenAIRE

    Buder, Fabian; Hamm, Ulrich; Bickel, Malte; Bien, Barbara; Michels, Paul

    2010-01-01

    Das Gesamtziel des vorliegenden Forschungsprojekts war es, eine detaillierte Informationsgrundlage zum tatsächlichen Kaufverhalten von deutschen Haushalten bei ökologischen Lebensmitteln auf der Basis von Haushaltspaneldaten zu erstellen. Dazu sollten zum einen relevante Aspekte des Kaufverhaltens von Haushalten bei Öko-Lebensmitteln im Zeitverlauf von 2004 bis 2008 analysiert und zum anderen die Einflussfaktoren des Kaufverhaltens bei Öko-Lebensmitteln für das Jahr 2008 identifiziert werden....

  11. Gewerbsmässigkeit im schweizerischen Luftrecht

    OpenAIRE

    Müller, Roland

    2005-01-01

    Der Begriff der Gewerbsmässigkeit hat im schweizerischen Luftrecht eine grosse Bedeutung. Werden gewerbsmässige Flüge ohne die entsprechenden Bewilligungen und Voraussetzungen durchgeführt, so resultieren gravierende zivilrechtliche, strafrechtliche und administrative Konsequenzen. In den massgebenden internationalen Luftfahrtabkommen findet sich keine Definition der Gewerbsmässigkeit, dies wird den einzelnen Staaten überlassen. Nur in den Joint Aviation Requirements und in der EU-Zollver...

  12. Toward an Intelligent Ion Mobility Spectrometer (IMS)

    International Nuclear Information System (INIS)

    McJunkin, Timothy R.; Scott, Jill R.; Miller, Carla J.

    2003-01-01

    The ultimate goal is to design and build a very smart ion mobility spectrometer (IMS) that can operate autonomously. To accomplish this, software capable of interpreting spectra so that it can be used in control loops for data interpretation as well as adjusting instrument parameters is being developed. Fuzzy logic and fuzzy numbers are used in this IMS spectra classification scheme. Fuzzy logic provides a straight forward method for developing a classification/detection system, whenever rules for classifying the spectra can be described linguistically. Instead of using 'max' and 'min' values, the product of the truth values is used to determine class membership. Using the product allows rule-bases that utilize the AND function to allow each condition to discount truth value in determining membership, while rule-bases with an OR function are allowed to accumulate membership. Fuzzy numbers allow encapsulation of the uncertainties due to ion mobility peak widths as well as measured instrumental parameters, such as pressure and temperature. Associating a peak with a value of uncertainty, in addition to making adjustments to the mobility calculation based on variations in measured parameters, enables unexpected shifts to be more reliably detected and accounted for; thereby, reducing the opportunity for 'false negative' results. The measure of uncertainty is anticipated to serve the additional purpose of diagnosing the operational conditions of the IMS instrument.

  13. Grand Prix Eurovision: Eine Fankultur im Medienzeitalter

    Directory of Open Access Journals (Sweden)

    Heinz Moser

    2017-06-01

    Full Text Available Der Grand Prix Eurovision ist seit Jahrzehnten eine der bekanntesten Unterhaltungssendungen im europäischen Raum. Dennoch erregte es Verwunderung, wenn der Schreibende Bekannten darüber berichtete, daß dies ein Forschungsgegenstand sei. Wurde von Interviews mit Grand Prix-Fans erzählt, so fielen schnell Aussagen wie: „Wie kann man sich nur für so etwas Abseitiges und Triviales wie den Grand Prix interessieren“. Dennoch bin ich der Meinung, daß Fankulturen für die entstehende Mediengesellschaft ein nicht unwichtiges Forschungsthema darstellen. Zwar geht es nicht um eine medienpädagogische Fragestellung im engeren Sinne; die Fans des Grand Prix Eurovision sind dem Jugendalter längst entwachsen. Dennoch handelt es sich bei Fangemeinschaften um Phänomene, die im Rahmen von Jugend- und Kinderkulturen von besonderer Relevanz sind. So meint Winter (1997, daß jugendliche Fanwelten eine bedeutende Rolle als Kristallisationspunkte kultureller Differenzierung spielen: ,Die Zugehörigkeit zu einer Fan weit ist Teil der jugendlichen Lebensbewältigung in der Postmoderne, denn in der Gemeinschaft der Fans können Jugendliche emotionale Allianzen eingehen, außeralltäglichen Beschäftigungen nachgehen, expressive Identitätsmuster gemeinschaftlich realisieren und sich mit ihrer Lebenssituation als Heranwachsende auseinandersetzen“ (Winter 1997, S. 51f..

  14. FANCD2 functions as a critical factor downstream of MiTF to maintain the proliferation and survival of melanoma cells.

    Science.gov (United States)

    Bourseguin, Julie; Bonet, Caroline; Renaud, Emilie; Pandiani, Charlotte; Boncompagni, Marina; Giuliano, Sandy; Pawlikowska, Patrycja; Karmous-Benailly, Houda; Ballotti, Robert; Rosselli, Filippo; Bertolotto, Corine

    2016-11-09

    Proteins involved in genetic stability maintenance and safeguarding DNA replication act not only against cancer initiation but could also play a major role in sustaining cancer progression. Here, we report that the FANC pathway is highly expressed in metastatic melanoma harboring the oncogenic microphthalmia-associated transcription factor (MiTF). We show that MiTF downregulation in melanoma cells lowers the expression of several FANC genes and proteins. Moreover, we observe that, similarly to the consequence of MiTF downregulation, FANC pathway silencing alters proliferation, migration and senescence of human melanoma cells. We demonstrate that the FANC pathway acts downstream MiTF and establish the existence of an epistatic relationship between MiTF and the FANC pathway. Our findings point to a central role of the FANC pathway in cellular and chromosomal resistance to both DNA damage and targeted therapies in melanoma cells. Thus, the FANC pathway is a promising new therapeutic target in melanoma treatment.

  15. Lessons after 3 years of running GENIUS-TF in Gran Sasso

    Energy Technology Data Exchange (ETDEWEB)

    Krivosheina, I V; Klapdor-Kleingrothaus, H V [Max-Planck-Institut fuer Kernphysik, PO 10 39 80, D-69029 Heidelberg (Germany)

    2006-10-01

    After operation of GENIUS-TF over 3 years with finally six naked Ge detectors (15 kg) in liquid nitrogen in Gran Sasso, we realize serious problems for realization of a full-size GENIUS-like experiment: (i) background from {sup 222}Rn diffusing into the setup, on a level far beyond the expectation. (ii) Limited long-term stability of naked detectors in liquid nitrogen. None of the six detectors is running after 3 years with the nominal high voltage. Three of the six detectors do not work at all any more. The HDMS (Heidelberg Dark Matter Search) setup at LNGS, operates the first enriched {sup 73}Ge detector worldwide, and looks for spin-dependent WIMP-nucleon coupling at the Gran Sasso Underground Laboratory. The results (85.48 kg d) improve the best present existing limits on the WIMP-neutron spin-dependent cross-section (obtained from {sup 129}Xe) for low WIMP masses (Klapdor-Kleingrothaus et al 2005 Phys. Lett. B 609 226-31)

  16. High fidelity analysis of BWR fuel assembly with COBRA-TF/PARCS and trace codes

    International Nuclear Information System (INIS)

    Abarca, A.; Miro, R.; Barrachina, T.; Verdu, G.; Soler, A.

    2013-01-01

    The growing importance of detailed reactor core and fuel assembly description for light water reactors (LWRs) as well as the sub-channel safety analysis requires high fidelity models and coupled neutronic/thermalhydraulic codes. Hand in hand with advances in the computer technology, the nuclear safety analysis is beginning to use a more detailed thermal hydraulics and neutronics. Previously, a PWR core and a 16 by 16 fuel assembly models were developed to test and validate our COBRA-TF/PARCS v2.7 (CTF/PARCS) coupled code. In this work, a comparison of the modeling and simulation advantages and disadvantages of modern 10 by 10 BWR fuel assembly with CTF/PARCS and TRACE codes has been done. The objective of the comparison is making known the main advantages of using the sub-channel codes to perform high resolution nuclear safety analysis. The sub-channel codes, like CTF, permits obtain accurate predictions, in two flow regime, of the thermalhydraulic parameters important to safety with high local resolution. The modeled BWR fuel assembly has 91 fuel rods (81 full length and 10 partial length fuel rods) and a big square central water rod. This assembly has been modeled with high level of detail with CTF code and using the BWR modeling parameters provided by TRACE. The same neutronic PARCS's model has been used for the simulation with both codes. To compare the codes a coupled steady state has be performed. (author)

  17. Thermal-hydraulic behaviour of the ITER TF system during a quench development

    International Nuclear Information System (INIS)

    Nicollet, S.; Lacroix, B.; Bessette, D.; Copetti, R.; Duchateau, J.L.; Coatanea-Gouachet, M.; Rodriguez-Mateos, F.

    2011-01-01

    In order to ensure the safety of the ITER TF magnets, a primary quench detection system has been foreseen, based on voltage detection. In addition, a secondary quench detection could rely on signals of thermo-hydraulic nature. As a matter of fact, the development of a quench in a CICC leads to significant variations of pressure and mass flow at the quenched pancake extremities. Analyses of the quench development have thus been performed using the coupled GANDALF and FLOWER codes. This tool allows to simulate the thermo-hydraulic behaviour of one CICC with a model of the external cryogenic circuit. The study has focused on the first seconds of the quench development, supposing that the quench has not been detected earlier by the primary detector. It is shown that signals regarding pressure, mass flow and temperature reach significant high values especially in the connecting feeder associated with the helium inlet. More detailed studies will be needed to select a secondary detector in this region.

  18. Evaluation and enhancement of COBRA-TF efficiency for LWR calculations

    International Nuclear Information System (INIS)

    Cuervo, Diana; Avramova, Maria; Ivanov, Kostadin; Miro, Rafael

    2006-01-01

    Detailed representations of the reactor core generate computational meshes with a high number of cells where the fluid dynamics equations must be solved. An exhaustive analysis of the CPU times needed by the thermal-hydraulic subchannel code COBRA-TF for different stages in the solution process has revealed that the solution of the linear system of pressure equations is the most time consuming process. To improve code efficiency two optimized matrix solvers, Super LU library and Krylov non-stationary iterative methods have been implemented in the code and their performance has been tested using a suite of five test cases. The results of performed comparative analyses have demonstrated that for large cases, the implementation of the Bi-Conjugate Gradient Stabilized (Bi-CGSTAB) Krylov method combined with the incomplete LU factorization with dual truncation strategy (ILUT) pre-conditioner reduced the time used by the code for the solution of the pressure matrix by a factor of 20. Both new solvers converge smoothly regardless of the nature of simulated cases and the mesh structures and improve the stability and accuracy of results compared to the classic Gauss-Seidel iterative method. The obtained results indicate that the direct inversion method is the best option for small cases

  19. BOREAS TF-10 NSA-YJP Tower Flux, Meteorological, and Porometry Data

    Science.gov (United States)

    McCaughey, J. Harry; Liblik, Laura; Hall, Forrest G. (Editor); Huemmrich, K. (Editor)

    2000-01-01

    The BOREAS TF-10 team collected tower flux and meteorological data at two sites, a fen and a young jack pine forest, near Thompson, Manitoba, Canada, as part of BOREAS. A preliminary data set was assembled in August 1993 while field testing the instrument packages, and at both sites data were collected from 15-Aug to 31-Aug. The main experimental period was in 1994, when continuous data were collected from the young jack pine site from 23-May to 20-Sep. Upon examination of the 1994 data set, it became clear that the behavior of the heat, water, and carbon dioxide fluxes throughout the whole growing season was an important scientific question, and that the 1994 data record was not sufficiently long to capture the character of the seasonal behavior of the fluxes. Thus, the young jack pine site was operated from 08-May to 07-Nov in 1996 in order to collect data from spring melt to autumn freeze-up. All variables are presented as 30-minute averages. Supporting data were also collected to describe the surface#s state and to provide the information, in association with the flux data, to build SVAT models. For the young jack pine site, these supporting data included stomatal conductance measurements. The data are stored in tabular ASCII files.

  20. BOREAS TF-10 NSA-Fen Tower Flux and Meteorological Data

    Science.gov (United States)

    McCaughey, J. Harry; Hall, Forrest G. (Editor); Huemmrich, Karl (Editor); Jelinski, Dennis E.

    2000-01-01

    The BOREAS TF-10 team collected tower flux and meteorological data at two sites, a fen and a young jack pine forest, near Thompson, Manitoba, Canada, as part of BOREAS. A preliminary data set was assembled in August 1993 while field testing the instrument packages, and at both sites data were collected from 15-Aug to 31-Aug. The main experimental period was in 1994, when continuous data were collected from 08-Apr to 23-Sep at the fen site. A very limited experiment was run in the spring/ summer of 1995, when the fen site tower was operated from 08-Apr to 14-Jun in support of a hydrology experiment in an adjoining feeder basin. Upon examination of the 1994 data set, it became clear that the behavior of the heat, water, and carbon dioxide fluxes throughout the whole growing season was an important scientific question, and that the 1994 data record was not sufficiently long to capture the character of the seasonal behavior of the fluxes. Thus, the fen site was operated in 1996 in order to collect data from spring melt to autumn freeze-up. Data were collected from 29-Apr to 05-Nov at the fen site. All variables are presented as 30-minute averages. The data are stored in tabular ASCII files.

  1. Cyberbullying und Empathie : affektive, kognitive und medienbasierte Empathie im Kontext von Cyberbullying im Kindes- und Jugendalter

    OpenAIRE

    Pfetsch, Jan; Müller, Christin R.; Ittel, Angela

    2014-01-01

    "Bei medial vermittelter Kommunikation sinkt sowohl die Hemmschwelle für aggressive Verhaltensweisen wie Cyberbullying als auch die Wahrscheinlichkeit empathischer Reaktionen. Im Fokus der vorliegenden Studie mit 979 Schülerinnen und Schülern der 4.-8. Klassen (M=12.01, SD=1.68 Jahre, 55% weiblich) stand die Frage, ob Cyberbullies geringere Ausprägungen für affektive, kognitive und medienbasierte Empathie aufweisen als Unbeteiligte. Empathie wurde im Selbst- und Peerbericht erhoben. Hypothese...

  2. Evaluation of in vivo quantification accuracy of the Ingenuity-TF PET/MR.

    Science.gov (United States)

    Maus, Jens; Schramm, Georg; Hofheinz, Frank; Oehme, Liane; Lougovski, Alexandr; Petr, Jan; Platzek, Ivan; Beuthien-Baumann, Bettina; Steinbach, Jörg; Kotzerke, Jörg; van den Hoff, Jörg

    2015-10-01

    The quantitative accuracy of standardized uptake values (SUVs) and tracer kinetic uptake parameters in patient investigations strongly depends on accurate determination of regional activity concentrations in positron emission tomography (PET) data. This determination rests on the assumption that the given scanner calibration is valid in vivo. In a previous study, we introduced a method to test this assumption. This method allows to identify discrepancies in quantitative accuracy in vivo by comparison of activity concentrations of urine samples measured in a well-counter with activity concentrations extracted from PET images of the bladder. In the present study, we have applied this method to the Philips Ingenuity-TF PET/MR since at the present stage, absolute quantitative accuracy of combined PET/MR systems is still under investigation. Twenty one clinical whole-body F18-FDG scans were included in this study. The bladder region was imaged as the last bed position and urine samples were collected afterward. PET images were reconstructed including MR-based attenuation correction with and without truncation compensation and 3D regions-of-interest (ROIs) of the bladder were delineated by three observers. To exclude partial volume effects, ROIs were concentrically shrunk by 8-10 mm. Then, activity concentrations were determined in the PET images for the bladder and for the urine by measuring the samples in a calibrated well-counter. In addition, linearity measurements of SUV vs singles rate and measurements of the stability of the coincidence rate of "true" events of the PET/MR system were performed over a period of 4 months. The measured in vivo activity concentrations were significantly lower in PET/MR than in the well-counter with a ratio of the former to the latter of 0.756 ± 0.060 (mean ± std. dev.), a range of 0.604-0.858, and a P value of 3.9 ⋅ 10(-14). While the stability measurements of the coincidence rate of "true" events showed no relevant deviation over

  3. Evaluation of in vivo quantification accuracy of the Ingenuity-TF PET/MR

    Energy Technology Data Exchange (ETDEWEB)

    Maus, Jens, E-mail: j.maus@hzdr.de; Schramm, Georg; Hofheinz, Frank; Lougovski, Alexandr; Petr, Jan; Steinbach, Jörg [PET Center, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, P.O. Box 510119, 01314 Dresden (Germany); Oehme, Liane; Beuthien-Baumann, Bettina; Kotzerke, Jörg [Department of Nuclear Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden (Germany); Platzek, Ivan [Department of Radiology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden (Germany); Hoff, Jörg van den [PET Center, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, P.O. Box 510119, 01314 Dresden, Germany and Department of Nuclear Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden (Germany)

    2015-10-15

    Purpose: The quantitative accuracy of standardized uptake values (SUVs) and tracer kinetic uptake parameters in patient investigations strongly depends on accurate determination of regional activity concentrations in positron emission tomography (PET) data. This determination rests on the assumption that the given scanner calibration is valid in vivo. In a previous study, we introduced a method to test this assumption. This method allows to identify discrepancies in quantitative accuracy in vivo by comparison of activity concentrations of urine samples measured in a well-counter with activity concentrations extracted from PET images of the bladder. In the present study, we have applied this method to the Philips Ingenuity-TF PET/MR since at the present stage, absolute quantitative accuracy of combined PET/MR systems is still under investigation. Methods: Twenty one clinical whole-body F18-FDG scans were included in this study. The bladder region was imaged as the last bed position and urine samples were collected afterward. PET images were reconstructed including MR-based attenuation correction with and without truncation compensation and 3D regions-of-interest (ROIs) of the bladder were delineated by three observers. To exclude partial volume effects, ROIs were concentrically shrunk by 8–10 mm. Then, activity concentrations were determined in the PET images for the bladder and for the urine by measuring the samples in a calibrated well-counter. In addition, linearity measurements of SUV vs singles rate and measurements of the stability of the coincidence rate of “true” events of the PET/MR system were performed over a period of 4 months. Results: The measured in vivo activity concentrations were significantly lower in PET/MR than in the well-counter with a ratio of the former to the latter of 0.756 ± 0.060 (mean ± std. dev.), a range of 0.604–0.858, and a P value of 3.9 ⋅ 10{sup −14}. While the stability measurements of the coincidence rate of

  4. Application of calorimetry to the assessment of the performance of ITER Nb3Sn TF conductor samples in SULTAN tests

    International Nuclear Information System (INIS)

    Richard, L Savoldi; Zanino, R

    2008-01-01

    In the frame of the International Thermonuclear Experimental Reactor (ITER), several short full-size Nb 3 Sn samples of candidate toroidal field (TF) conductors were tested in 2007 at the SULTAN facility, PSI Villigen, Switzerland, in conditions relevant to the ITER TF (background magnetic field of 10.78 T and transport current of 68 kA). The performance of a SULTAN sample is determined by the current sharing temperature T CS . This can be obtained in principle from voltage measurements along the conductor sample, but the procedure is not free of issues and ambiguities. Here a complementary approach, based on the calorimetric assessment of the Joule heating due to current sharing, is critically discussed. Suitable algorithms are defined and the respective error bars are estimated, also based on numerical thermal-hydraulic modeling. The calorimetric approach is then applied to assess the performance of the samples tested in 2007 and compared with the results of the standard (electrical) approach

  5. Fusion of Potentiometric & Voltammetric Electronic Tongue for Classification of Black Tea Taste based on Theaflavins (TF) Content

    Science.gov (United States)

    Bhattacharyya, Nabarun; Legin, Andrey; Papieva, Irina; Sarkar, Subrata; Kirsanov, Dmitry; Kartsova, Anna; Ghosh, Arunangshu; Bandyopadhyay, Rajib

    2011-09-01

    Black tea is an extensively consumed beverage worldwide with an expanding market. The final quality of black tea depends upon number of chemical compounds present in the tea. Out of these compounds, theaflavins (TF), which is responsible for astringency in black tea, plays an important role in determining the final taste of the finished black tea. The present paper reports our effort to correlate the theaflavins contents with the voltammetric and potentiometric electronic tongue (e-tongue) data. Noble metal-based electrode array has been used for collecting data though voltammetric electronic tongue where as liquid filled membrane based electrodes have been used for potentiometric electronic tongue. Black tea samples with tea taster score and biochemical results have been collected from Tea Research Association, Tocklai, India for the analysis purpose. In this paper, voltammetric and potentiometric e-tongue responses are combined to demonstrate improvement of cluster formation among tea samples with different ranges of TF values.

  6. Association study between four polymorphisms in the HFE, TF and TFR genes and Parkinson's disease in southern Italy.

    Science.gov (United States)

    Greco, Valentina; De Marco, Elvira Valeria; Rocca, Francesca Emanuela; Annesi, Ferdinanda; Civitelli, Donatella; Provenzano, Giovanni; Tarantino, Patrizia; Scornaienchi, Vittorio; Pucci, Franco; Salsone, Maria; Novellino, Fabiana; Morelli, Maurizio; Paglionico, Sandra; Gambardella, Antonio; Quattrone, Aldo; Annesi, Grazia

    2011-06-01

    Iron overload may lead to neurodegenerative disorders such as Parkinson's disease (PD) and alterations of iron-related genes might be involved in the pathogenesis of this disease. The gene of haemochromatosis (HFE) encodes the HFE protein which interacts with the transferrin receptor (TFR), lowering its affinity for iron-bound transferrin (TF). We examined four known polymorphisms, C282Y and H63D in the HFE gene, G258S in the TF gene and S82G in the TFR gene, in 181 sporadic PD patients and 180 controls from Southern Italy to investigate their possible role in susceptibility to PD. No significant differences were found in genotype and allele frequencies between PD and controls for all the polymorphisms studied, suggesting that these variants do not contribute significantly to the risk of PD.

  7. Implementation of non-condensable gases condensation suppression model into the WCOBRA/TRAC-TF2 LOCA safety evaluation code

    Energy Technology Data Exchange (ETDEWEB)

    Liao, J.; Cao, L.; Ohkawa, K.; Frepoli, C. [LOCA Integrated Services I, Westinghouse Electric Company, 1000 Westinghouse Drive, Cranberry Township, PA 16066 (United States)

    2012-07-01

    The non-condensable gases condensation suppression model is important for a realistic LOCA safety analysis code. A condensation suppression model for direct contact condensation was previously developed by Westinghouse using first principles. The model is believed to be an accurate description of the direct contact condensation process in the presence of non-condensable gases. The Westinghouse condensation suppression model is further revised by applying a more physical model. The revised condensation suppression model is thus implemented into the WCOBRA/TRAC-TF2 LOCA safety evaluation code for both 3-D module (COBRA-TF) and 1-D module (TRAC-PF1). Parametric study using the revised Westinghouse condensation suppression model is conducted. Additionally, the performance of non-condensable gases condensation suppression model is examined in the ACHILLES (ISP-25) separate effects test and LOFT L2-5 (ISP-13) integral effects test. (authors)

  8. Security in the internet; Sicherheitsaspekte im Internet

    Energy Technology Data Exchange (ETDEWEB)

    Seibel, R.M.M.; Kocher, K.; Landsberg, P. [Witten-Herdecke Univ., Witten (Germany). Inst. fuer Diagnostische und Interventionelle Radiologie

    2000-04-01

    Aim of the study: Is it possible to use the Internet as a secure media for transport of telemedicine? Which risks exist for routine use? In this article state of the art methods of security were analysed. Telemedicine in the Internet has severe risks, because patient data and hospital data of a secure Intranet can be manipulated by connecting it to the Web. Conclusions: Establishing of a firewall and the introduction of HPC (Health Professional Card) are minimizing the risk of un-authorized access to the hospital server. HPC allows good safety with digital signature and authentication of host and client of medical data. For secure e-mail PGP (Pretty Good Privacy) is easy to use as a standard protocol. Planning all activities exactly as well as following legal regulations are important requisites for reduction of safety risks in Internet. (orig.) [German] Ziele der Studie und Analyse: Es sollten die Fragen beantwortet werden, ob es moeglich ist, das Internet als sicheres Uebermittlungsmedium fuer Telemedizin zu nutzen und welche Sicherheitsrisiken bestehen. Dazu wurden die gaengigen Sicherheitsmethoden analysiert. Telemedizin im Internet ist mit Sicherheitsrisiken behaftet, die durch die Oeffnung eines Intranets mit der Moeglichkeit zur unberechtigten Manipulation von aussen bedingt sind. Schlussfolgerung: Diese Sicherheitsrisiken koennen durch eine Firewall weitgehend unterbunden werden. Chipkarten wie die Health professional card ermoeglichen eine hohe Sicherheit bei digitaler Signatur und sicherer Authentifikation der Sender und Empfaenger von Daten im Internet. Auch Standards wie Pretty good privacy sind inzwischen fuer sichere e-mails einfach einzusetzen. Wichtige Voraussetzung fuer die Reduktion von Sicherheitsrisiken ist unter Beruecksichtigung der gesetzlichen Vorgaben die exakte Planung aller Aktivitaeten im Internet, bei denen medizinische Patientendaten versandt werden sollen, in einem Team aus Aerzten und Informatikern. (orig.)

  9. Oxotremorine treatment reduces repetitive behaviors in BTBR T+ tf/J mice

    Directory of Open Access Journals (Sweden)

    Dionisio A. Amodeo

    2014-08-01

    Full Text Available Repetitive behaviors with restricted interests is one of the core criteria for the diagnosis of autism spectrum disorder (ASD. Current pharmacotherapies that target the dopaminergic or serotonergic systems have limited effectiveness in treating repetitive behaviors. Previous research has demonstrated that administration of muscarinic cholinergic receptor (mAChR antagonists can exacerbate motor stereotypies while mAChR agonists reduce stereotypies. The present study determined whether the mAChR agonist, oxotremorine affected repetitive behaviors in the BTBR T+ tf/J (BTBR mouse model of autism. To test the effects of oxotremorine on repetitive behaviors, marble burying and grooming behavior were measured in BTBR mice and compared to that in C57BL/6J (B6 mice. The effects of oxotremorine on locomotor activity was also measured. Thirty minutes before each test, mice received an intraperitoneal injection of saline, 0.001 mg or 0.01 mg of oxotremorine methiodide. Saline- treated BTBR mice exhibited increased marble burying and self-grooming behavior compared to that of saline-treated B6 mice. Oxotremorine significantly reduced marble burying and self-grooming behavior in BTBR mice, but had no significant effect in B6 mice. In addition, oxotremorine did not affect locomotor activity in BTBR mice, but significantly reduced locomotor activity in B6 mice at the 0.01 mg dose. These findings demonstrate that activation of mAChRs reduces repetitive behavior in the BTBR mouse and suggest that treatment with a mAChR agonist may be effective in reducing repetitive behaviors in ASD.

  10. Ion Mobility Spectrometer / Mass Spectrometer (IMS-MS)

    Energy Technology Data Exchange (ETDEWEB)

    Hunka, Deborah E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Austin, Daniel [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2005-10-01

    The use of Ion Mobility Spectrometry (IMS)in the Detection of Contraband Sandia researchers use ion mobility spectrometers for trace chemical detection and analysis in a variety of projects and applications. Products developed in recent years based on IMS-technology include explosives detection personnel portals, the Material Area Access (MAA) checkpoint of the future, an explosives detection vehicle portal, hand-held detection systems such as the Hound and Hound II (all 6400), micro-IMS sensors (1700), ordnance detection (2500), and Fourier Transform IMS technology (8700). The emphasis to date has been on explosives detection, but the detection of chemical agents has also been pursued (8100 and 6400).

  11. [Bernt Ahrenholz : Verweise mit Demonstrativa im Gesprochenen Deutsch...] / Klaus Geyer

    Index Scriptorium Estoniae

    Geyer, Klaus

    2008-01-01

    Arvustus: Ahrenholz, Bernt. Verweise mit Demonstrativa im gesprochenen Deutsch : Grammatik, Zweitspracherwerb und Deutsch als Fremdsprache. Berlin ; New York : de Gruyter, 2007. (Linguistik - Impulse & Tendenzen ; 17)

  12. Kriminologie und Kriminalistik im Zugriff der Geschichtswissenschaft

    Directory of Open Access Journals (Sweden)

    Peter-Alexis Albrecht

    2007-01-01

    Full Text Available Rezensierte Werke:Silviana Galassi, Kriminologie im Deutschen Kaiserreich. Geschichte einer gebrochenen Verwissen­schaftlichung, Stuttgart: Franz Steiner Verlag 2004, 452 S., ISBN 3-515-08352-9; Peter Becker, Dem Täter auf der Spur. Eine Geschichte der Kriminalistik, Darmstadt: Primus Verlag 2005, 287 S., ISBN 3-89678-275-4; Peter Becker, Richard F. Wetzell (Hg., Criminals and their Scientists. The History of Criminology in International Perspective, Cambridge: Cambridge University Press 2006, 492 S., ISBN 0-521-81012-4

  13. Im Bild sprechen: Cixous Visual Instruction: Cixous

    OpenAIRE

    Jens E. Sennewald

    2006-01-01

    Gemeinsam von Künstlern und Wissenschaftlern/Philosophen erstellte Bücher sind selten und nicht immer erfolgreich. Eines der Fährnisse ist das Verhältnis zwischen bildlichen und schriftlichen Anteilen: Nicht selten wird der künstlerische Anteil zur Illustration der dominierenden Schrift. Eine Neupositionierung des Bildes im Buch ist nun der amerikanischen Künstlerin Roni Horn gelungen. Mehr als „sujet“ ihres Buches, ist die französische Philosophin Hélène Cixous gleichsam instruierende „Stimm...

  14. Corporate Venture Capital im Bankensektor: Eine Fallstudie

    OpenAIRE

    Maxin, Hannes

    2015-01-01

    Die Digitalisierung der Gesellschaft beeinflusst zunehmend das klassische Bankgeschäft, was durch die Erfolge vieler junger FinTech-Unternehmen verdeutlicht wird. Der damit verbundene Innovationsdruck führte dazu, dass die Commerzbank AG im Oktober 2013 die Main Incubator GmbH gründete. Mithilfe dieser Corporate Venture Capital-Gesellschaft (CVC-Gesellschaft) versucht die Frankfurter Großbank, eine Kooperation mit den neuen Wettbewerbern einzugehen, um mögliche Synergiepotenziale für das eige...

  15. In-Session Caregiver Behavior Predicts Symptom Change in Youth Receiving Trauma-Focused Cognitive Behavioral Therapy (TF-CBT)

    Science.gov (United States)

    Yasinski, Carly; Hayes, Adele; Ready, C. Beth; Cummings, Jorden A.; Berman, Ilana S.; McCauley, Thomas; Webb, Charles; Deblinger, Esther

    2016-01-01

    Objective Involving caregivers in trauma-focused treatments for youth has been shown to result in better outcomes, but it is not clear which in-session caregiver behaviors enhance or inhibit this effect. The current study examined the associations between caregiver behaviors during Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) and youth cognitive processes and symptoms. Method Participants were a racially diverse sample of Medicaid-eligible youth (ages 7–17) and their non-offending caregivers (N= 71 pairs) who received TF-CBT through an effectiveness study in a community setting. Caregiver and youth processes were coded from audio-recorded sessions, and outcomes were measured using the Child Behavior Checklist (CBCL) and UCLA PTSD Reaction Index for DSM-IV (UPID) at 3, 6, 9, and 12 months post-intake. Results Piecewise linear growth curve modeling revealed that during the trauma narrative phase of TF-CBT, caregivers’ cognitive-emotional processing of their own and their child's trauma-related reactions predicted decreases in youth internalizing and externalizing symptoms over treatment. Caregiver support predicted lower internalizing symptoms over follow-up. In contrast, caregiver avoidance and blame of the child predicted worsening of youth internalizing and externalizing symptoms over follow-up. Caregiver avoidance early in treatment also predicted worsening of externalizing symptoms over follow-up. During the narrative phase, caregiver blame and avoidance were correlated with more child overgeneralization of trauma beliefs, and blame was also associated with less child accommodation of balanced beliefs. Conclusions The association between in-session caregiver behaviors and youth symptomatology during and after TF-CBT highlights the importance of assessing and targeting these behaviors to improve clinical outcomes. PMID:27618641

  16. In-session caregiver behavior predicts symptom change in youth receiving trauma-focused cognitive behavioral therapy (TF-CBT).

    Science.gov (United States)

    Yasinski, Carly; Hayes, Adele M; Ready, C Beth; Cummings, Jorden A; Berman, Ilana S; McCauley, Thomas; Webb, Charles; Deblinger, Esther

    2016-12-01

    Involving caregivers in trauma-focused treatments for youth has been shown to result in better outcomes, but it is not clear which in-session caregiver behaviors enhance or inhibit this effect. The current study examined the associations between caregiver behaviors during Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) and youth cognitive processes and symptoms. Participants were a racially diverse sample of Medicaid-eligible youth (ages 7-17) and their nonoffending caregivers (N = 71 pairs) who received TF-CBT through an effectiveness study in a community setting. Caregiver and youth processes were coded from audio-recorded sessions, and outcomes were measured using the Child Behavior Checklist (CBCL) and UCLA PTSD Reaction Index for Diagnostic and Statistical Manual for Mental Disorders-Fourth Edition (DSM-IV; UPID) at 3, 6, 9, and 12 months postintake. Piecewise linear growth curve modeling revealed that during the trauma narrative phase of TF-CBT, caregivers' cognitive-emotional processing of their own and their child's trauma-related reactions predicted decreases in youth internalizing and externalizing symptoms over treatment. Caregiver support predicted lower internalizing symptoms over follow-up. In contrast, caregiver avoidance and blame of the child predicted worsening of youth internalizing and externalizing symptoms over follow-up. Caregiver avoidance early in treatment also predicted worsening of externalizing symptoms over follow-up. During the narrative phase, caregiver blame and avoidance were correlated with more child overgeneralization of trauma beliefs, and blame was also associated with less child accommodation of balanced beliefs. The association between in-session caregiver behaviors and youth symptomatology during and after TF-CBT highlights the importance of assessing and targeting these behaviors to improve clinical outcomes. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  17. Preliminary LOCA analysis of the westinghouse small modular reactor using the WCOBRA/TRAC-TF2 thermal-hydraulics code

    Energy Technology Data Exchange (ETDEWEB)

    Liao, J.; Kucukboyaci, V. N.; Nguyen, L.; Frepoli, C. [Westinghouse Electric Company, 1000 Westinghouse Drive, Cranberry Township, PA 16066 (United States)

    2012-07-01

    The Westinghouse Small Modular Reactor (SMR) is an 800 MWt (> 225 MWe) integral pressurized water reactor (iPWR) with all primary components, including the steam generator and the pressurizer located inside the reactor vessel. The reactor core is based on a partial-height 17x17 fuel assembly design used in the AP1000{sup R} reactor core. The Westinghouse SMR utilizes passive safety systems and proven components from the AP1000 plant design with a compact containment that houses the integral reactor vessel and the passive safety systems. A preliminary loss of coolant accident (LOCA) analysis of the Westinghouse SMR has been performed using the WCOBRA/TRAC-TF2 code, simulating a transient caused by a double ended guillotine (DEG) break in the direct vessel injection (DVI) line. WCOBRA/TRAC-TF2 is a new generation Westinghouse LOCA thermal-hydraulics code evolving from the US NRC licensed WCOBRA/TRAC code. It is designed to simulate PWR LOCA events from the smallest break size to the largest break size (DEG cold leg). A significant number of fluid dynamics models and heat transfer models were developed or improved in WCOBRA/TRAC-TF2. A large number of separate effects and integral effects tests were performed for a rigorous code assessment and validation. WCOBRA/TRAC-TF2 was introduced into the Westinghouse SMR design phase to assist a quick and robust passive cooling system design and to identify thermal-hydraulic phenomena for the development of the SMR Phenomena Identification Ranking Table (PIRT). The LOCA analysis of the Westinghouse SMR demonstrates that the DEG DVI break LOCA is mitigated by the injection and venting from the Westinghouse SMR passive safety systems without core heat up, achieving long term core cooling. (authors)

  18. Politische Inhalte im Internet: Angebot und Nachfrage politischer Inhalte im World Wide Web am Beispiel von Volksabstimmungen in der Schweiz

    OpenAIRE

    Rademacher, Patrick Horst Josef

    2010-01-01

    Welche Bedeutung kommt dem Internet in der Politikvermittlung zu? Dieser Frage geht Patrick Rademacher nach, indem er untersucht, welche Anbieter politische Inhalte im Internet zur Verfügung stellen, wie sie dabei vorgehen und wie die Struktur der Inhalte beschaffen ist. Darüber hinaus analysiert er, inwiefern die online angebotenen Inhalte auf eine Nachfrage durch die Bürger treffen. Im Untersuchungskontext von Volksabstimmungen in der Schweiz hat der Autor hierfür im Jahr 2008 umfangreiche ...

  19. bildbild – visuelle Kompetenz im Unterricht

    Directory of Open Access Journals (Sweden)

    Norbert Grube

    2013-05-01

    Full Text Available Der vorliegende Artikel stellt das Webseiten-Projekt bildbild vor. Der Webseite liegt die Motivation zugrunde, Schülerinnen und Schüler für ein Nachdenken über globale Themen zu sensibilisieren. Ein solches Nachdenken ist immer auch eines über bildlich vermittelte Wirklichkeit. Es ist mit bildbild ein Anliegen, angesichts einer allseits konstatierten «Bilderflut» ein didaktisches Medium zu entwickeln, das einen Fundus an historischen und aktuellen Fotografien zur Verfügung stellt und diese so aufbereitet, dass sie gerade nicht hinter ihrer illustrativen Funktion verschwinden. Dadurch sollen die Bilder für ein selbständiges Lernen auf dem Weg hin zu einer visuellen Kompetenz einsetzbar gemacht werden. Der Beitrag beleuchtet die Entwicklung der Webseite vor dem Hintergrund kulturkritischer Haltungen zum Bild seit der Moderne sowie im Rahmen dessen, was seit den 1970er Jahren im pädagogischen Kontext als Visual Literacy diskutiert und gefördert wird. Dabei wird auch auf die medialen Potenziale einer Webseite für die Bildlesekompetenz von Jugendlichen eingegangen.

  20. Thermal Degradation Study of IM7/DMBZ-15 High Temperature Composite by TGA/FTIR

    National Research Council Canada - National Science Library

    Nadler, Melvin

    2003-01-01

    (U) High temperature graphite composites such as IM7/8552 epoxy, IM7/5250 BMI, and IM7/DMBZ-15 polyimide show blistering and/or "catastrophic" delamination when rapidly heated to temperatures above...

  1. The future of the IMS Learning Design specification: a critical look

    NARCIS (Netherlands)

    Sloep, Peter

    2009-01-01

    P. B. Sloep (2009). The future of the IMS Learning Design specification: a critical look. Presentation at the IMS Learning Design seminar 'The future of IMS Learning Design'. December, 10, 2009, Wollongong, Australia: University of Wollongong.

  2. Digitalisierung im Verteilnetz: Evolution oder Revolution anhand konkreter Beispiele

    Science.gov (United States)

    Krone, Oliver; Bachmann, Maurus

    Durch die Integration der neuen erneuerbaren Energien steht das Stromnetz vor großen Herausforderungen. Das Energiesystem als Gesamtes und die Verteilnetze im Speziellen werden smart. Anhand konkreter Beispiele wird aufgezeigt, wie die Digitalisierung im Elektrizitätsnetz voranschreitet. Diese Entwicklung ist eine Evolution, nicht aber eine Revolution.

  3. [Einheit und Vielfalt in der Rechtsgeschichte im Ostseeraum] / Marelle Leppik

    Index Scriptorium Estoniae

    Leppik, Marelle

    2013-01-01

    Arvustus: Einheit und Vielfalt in der Rechtsgeschichte im Ostseeraum. Unity and plurality in the legal history of the Baltic Sea area Sechster Rechtshistorikertag im Ostseeraum, 3.-5. Juni 2010 Tartu (Estland) / Riga (Lettland9. Hrsg. von Marju Luts-Sootak, Sanita Osipova und Frank L. Schäfer. (Rechtshistorische Reihe, Bd. 428.) Land. Frankfurt am Main u. a. 2012

  4. Information Management System (Ims) For Gender Mainstreaming In ...

    African Journals Online (AJOL)

    Information Management System (IMS) is an essential tool in supporting the provision of information needed for planning and decision making in any organization. Proper IMS facilitates the smooth flow of information both vertical and horizontal. This paper presents the findings of a survey on information needs of the Gender ...

  5. WISE TF: A MID-INFRARED, 3.4 μm EXTENSION OF THE TULLY-FISHER RELATION USING WISE PHOTOMETRY

    International Nuclear Information System (INIS)

    Lagattuta, David J.; Mould, Jeremy R.; Staveley-Smith, Lister; Hong Tao; Springob, Christopher M.; Masters, Karen L.; Koribalski, Bärbel S.; Jones, D. Heath

    2013-01-01

    We present a mid-infrared Tully-Fisher (TF) relation using photometry from the 3.4 μm W1 band of the Wide-field Infrared Survey Explorer (WISE) satellite. The WISE TF relation is formed from 568 galaxies taken from the all-sky 2MASS Tully-Fisher (2MTF) galaxy catalog, spanning a range of environments including field, group, and cluster galaxies. This constitutes the largest mid-infrared TF relation constructed to date. After applying a number of corrections to galaxy magnitudes and line widths, we measure a master TF relation given by M corr = –22.24 – 10.05[log (W corr ) – 2.5], with an average dispersion of σ WISE = 0.686 mag. There is some tension between WISE TF and a preliminary 3.6 μm relation, which has a shallower slope and almost no intrinsic dispersion. However, our results agree well with a more recent relation constructed from a large sample of cluster galaxies. We additionally compare WISE TF to the near-infrared 2MTF template relations, finding a good agreement between the TF parameters and total dispersions of WISE TF and the 2MTF K-band template. This fact, coupled with typical galaxy colors of (K – W1) ∼ 0, suggests that these two bands are tracing similar stellar populations, including the older, centrally-located stars in the galactic bulge which can (for galaxies with a prominent bulge) dominate the light profile.

  6. FANCD2 functions as a critical factor downstream of MiTF to maintain the proliferation and survival of melanoma cells

    OpenAIRE

    Julie Bourseguin; Caroline Bonet; Emilie Renaud; Charlotte Pandiani; Marina Boncompagni; Sandy Giuliano; Patrycja Pawlikowska; Houda Karmous-Benailly; Robert Ballotti; Filippo Rosselli; Corine Bertolotto

    2016-01-01

    Proteins involved in genetic stability maintenance and safeguarding DNA replication act not only against cancer initiation but could also play a major role in sustaining cancer progression. Here, we report that the FANC pathway is highly expressed in metastatic melanoma harboring the oncogenic microphthalmia-associated transcription factor (MiTF). We show that MiTF downregulation in melanoma cells lowers the expression of several FANC genes and proteins. Moreover, we observe that, similarly t...

  7. WISE TF: A MID-INFRARED, 3.4 {mu}m EXTENSION OF THE TULLY-FISHER RELATION USING WISE PHOTOMETRY

    Energy Technology Data Exchange (ETDEWEB)

    Lagattuta, David J.; Mould, Jeremy R. [Centre for Astrophysics and Supercomputing, Swinburne University of Technology, P.O. Box 218, Hawthorn, VIC 3122 (Australia); Staveley-Smith, Lister; Hong Tao; Springob, Christopher M. [ARC Centre of Excellence for All-sky Astrophysics (CAASTRO), Redfern, NSW (Australia); Masters, Karen L. [Institute for Cosmology and Gravitation, University of Portsmouth, Dennis Sciama Building, Burnaby Road, Portsmouth, PO1 3FX (United Kingdom); Koribalski, Baerbel S. [CSIRO Astronomy and Space Science, Australia Telescope National Facility (ATNF) P.O. Box 76, Epping, NSW 1710 (Australia); Jones, D. Heath, E-mail: dlagattu@astro.swin.edu.au [School of Physics, Monash University, Clayton, VIC 3800 (Australia)

    2013-07-10

    We present a mid-infrared Tully-Fisher (TF) relation using photometry from the 3.4 {mu}m W1 band of the Wide-field Infrared Survey Explorer (WISE) satellite. The WISE TF relation is formed from 568 galaxies taken from the all-sky 2MASS Tully-Fisher (2MTF) galaxy catalog, spanning a range of environments including field, group, and cluster galaxies. This constitutes the largest mid-infrared TF relation constructed to date. After applying a number of corrections to galaxy magnitudes and line widths, we measure a master TF relation given by M{sub corr} = -22.24 - 10.05[log (W{sub corr}) - 2.5], with an average dispersion of {sigma}{sub WISE} = 0.686 mag. There is some tension between WISE TF and a preliminary 3.6 {mu}m relation, which has a shallower slope and almost no intrinsic dispersion. However, our results agree well with a more recent relation constructed from a large sample of cluster galaxies. We additionally compare WISE TF to the near-infrared 2MTF template relations, finding a good agreement between the TF parameters and total dispersions of WISE TF and the 2MTF K-band template. This fact, coupled with typical galaxy colors of (K - W1) {approx} 0, suggests that these two bands are tracing similar stellar populations, including the older, centrally-located stars in the galactic bulge which can (for galaxies with a prominent bulge) dominate the light profile.

  8. Recurrent safety inspection of German nuclear power plant - performance, schedule and goals. As of 11 August 1995; Periodische Sicherheitsueberpruefung (PSUe) fuer deutsche Kernkraftwerke - Durchfuehrung der PSUe. Vom 11. August 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-23

    The recurrent safety inspection is intended as an inspection supplementing the continuous operation monitoring activities within the framework given by the supervisory activities of the supervisory authority. The first recurrent safety inspection is scheduled to be performed about ten years after start-up of the plant, with subsequent inspection intervals to cover ten-year periods, and recorded operating and monitoring results to be taken into account at each recurrent inspection. The purpose of the recurrent safety inspections is to ascertain that post-inspection operation of the plant meets the then required safety standards. Significant testing results of the latest inspection are to be analysed and compared with regard to the current state of the art and operating results accumulated since the previous inspection, for subsequent definition of enhancements if required. (orig./HP) [Deutsch] Die PSUesoll eine Ergaenzung der staendigen Ueberpruefung im Rahmen der atomrechtlichen Aufsicht ueber den Betrieb sein. Eine erstmalige PSUesoll etwa zehn Jahre nach Inbetriebnahme erfolgen. Die weiteren Ueberpruefungen sollen danach jeweils im Abstand von etwa zehn Jahren stattfinden. Die zwischenzeitlichen Erfahrungen aus Betrieb und Aufsicht sind einzubeziehen. Ziel der PSUemuss sein, festzustellen, ob die Anlage auch im Hinblick auf den kuenftigen Betrieb ein ausreichendes Sicherheitsniveau besitzt. Zu diesem Zweck muessen repraesentative Ereignisse dann detailliert untersucht werden, wenn neue Erkenntnisse aus Forschung und Entwicklung sowie aus der Betriebserfahrung seit der letzten Periodischen Sicherheitsueberpruefung dies erfordern. (orig./HP)

  9. Support interoperability and reusability of emerging forms of assessment: Some issues on integrating IMS LD with IMS QTI

    NARCIS (Netherlands)

    Miao, Yongwu; Boon, Jo; Van der Klink, Marcel; Sloep, Peter; Koper, Rob

    2009-01-01

    Miao, Y., Boon, J., Van der Klink, M., Sloep, P. B., & Koper, R. (2011). Support interoperability and reusability of emerging forms of assessment: Some issues on integrating IMS LD with IMS QTI. In F. Lazarinis, S. Green, & E. Pearson (Eds.), E-Learning Standards and Interoperability: Frameworks

  10. Die Rule of Law im Völker- und im Europarecht – aktuelle Probleme

    Directory of Open Access Journals (Sweden)

    Helmut Tichy

    2015-04-01

    Full Text Available Diese am 5. März 2015 in Graz gehaltene Antrittsvorlesung eines Praxisprofessors, der im Hauptberuf Leiter des Völkerrechtsbüros im österreichischen Außenministerium ist, beschäftigt sich mit dem Begriff der Herrschaft des Rechts in den internationalen Beziehungen (Rule of Law und mit den Möglichkeiten Österreichs, zur Stärkung der Rule of Law und zur Lösung aktueller Probleme beizutragen. Dabei werden insbesondere die Mitwirkung an Kodifikationsbemühungen und an der Verbesserung der Einhaltung des humanitären Völkerrechts, die Umsetzung der Menschenrechte (auch in Österreich und Fragen der internationalen Gerichtsbarkeit angesprochen.

  11. Antarctic observations available for IMS correlative analyses

    International Nuclear Information System (INIS)

    Rycroft, M.J.

    1982-01-01

    A review is provided of the wide-ranging observational programs of 25 stations operating on and around the continent of Antarctica during the International Magnetospheric Study (IMS). Attention is given to observations of geomagnetism, short period fluctuations of the earth's electromagnetic field, observations of the ionosphere and of whistler mode signals, observational programs in ionospheric and magnetospheric physics, upper atmosphere physics observations, details of magnetospheric programs conducted at Kerguelen, H-component magnetograms, magnetic field line oscillations, dynamic spectra of whistlers, and the variation of plasmapause position derived from recorded whistlers. The considered studies suggest that, in principle, if the level of magnetic activity is known, predictions can be made concerning the time at which the trough occurs, and the shape and the movement of the main trough

  12. FUNKTIONSLOGIK TERRORISTISCHER PROPAGANDA IM BEWEGTEN BILD

    Directory of Open Access Journals (Sweden)

    Stefan Christoph

    2015-09-01

    Full Text Available Die Medienfront ist heute ein wichtiger Kriegsschauplatz, den viele neben Land, Wasser und Luft für gleich wichtig halten. Terroristen fühlen sich in sozialen Medien wohler als man denken könnte. Im Netz können sie die asymmetrische Kräfteverteilung überwinden, die sie in der offenen Feldschlacht unterlegen sein ließe. Terroristen machen sich das Bild zur Waffe und produzieren erst durch die Positionierung an der Medienfront Sinn in ihren Taten. Ohne ein Bekennerschreiben, ein Abschiedsvideo des Attentäters oder ein letztes Posting im sozialen Netzwerk wäre ein Bombenanschlag nichts als ein Kapitalverbrechen. Durch die terroristische Kommunikationsstrategie wird das Verbrechen erst zum terroristischen Akt. Das ist die theoretische Grundannahme dieses Aufsatzes. Ohne Medienberichterstattung könnten terroristische Organisationen nicht existieren. Durch die Entwicklung des Web 2.0 und insbesondere sozialer Medien kommen terroristische Organisationen heutzutage aber ganz ohne das Verschicken von Videotapes an Fernsehsender aus. Durch YouTube und andere Kanäle, können sie die Adressaten ihrer Botschaften direkt und ohne zwischengeschaltete Journalistinnen und Journalisten erreichen. So ist es nicht erstaunlich, dass terroristische Organisationen sich eine gewisse Expertise im Umgang mit sozialen Medien zugelegt haben. Al-Qaida hat seine eigene Medienabteilung, auch die kolumbianischen FARC arbeiten sehr professionell und welchen Einfluss der Islamische Staat im Internet ausübt ist inzwischen bereits Gegenstand einiger Reportagen und Untersuchungen geworden. Die diesem Aufsatz zugrundeliegende Arbeit hat sich mit neun verschiedenen Videos aus dem Umfeld von al-Qaida, der IRA und der FARC beschäftigt und versucht, aus dem analytischen Vergleich dieser Videos Rückschlüsse über terroristische Medienmacher und die terroristischen Organisationen selbst zu ziehen. Wie schnell und suggestiv die Videos arbeiten, ist etwa davon abh

  13. Temporary provision against Kernkraftwerk Biblis dismissed

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    With its decision of November 19, 1979 - VIII IG 13/79 -, the Administrative Court of Hesse has refused the complaint of a Darmstadt resident whose application for a temporary provision interdicting further operation of the power plant units Biblis A and B had been refused by the Darmstadt Administrative Court. The costs of the procedure, including the extra-judicial costs of the witnesses heard, are to be paid by the plaintiff. The value in litigation was raised to DM 10 000,-. (orig./HP) 891 HP/orig.- 892 CKA [de

  14. Expert report of ENSI on the request of KKN AG for a general license - Project 'New nuclear power plant Niederamt'; Gutachten des ENSI zum Rahmenbewilligungsgesuch der KKN AG. Neubauprojekt Kernkraftwerk Niederamt

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-09-15

    The 'Kernkraftwerk Niederamt AG' (KKN) Company submitted to the Swiss Federal Inspectorate of Nuclear Safety (ENSI) a request for a general license for a new power plant to be built near to the Goesgen power plant. According to the law, all damage risks with a probability higher than 10{sup -4}/a must be taken into account through protection measures. The considered risks concern the power plant itself as well as the population in the neighbourhood and the environment. The purpose of the general license is to demonstrate that the site chosen for the foreseen power plant is acceptable and that the risks can be counteracted through adequate measures. The buildings of the power plant and their partition over the two banks of the Aare River are briefly described. The reactor is a Light Water Reactor of third generation with a maximum thermal power of 5.8 GW{sub th}. The main cooling is provided by a hybrid system of water evaporation and air heating, what reduces the plume at the exit of the cooling tower. First, it is demonstrated that, in the case of a very unlikely severe accident in the power plant, the people in the neighbourhood can be evacuated quickly. Then, numerous types of possible accidents in the neighbourhood of the power plant are analyzed in order to settle their possible negative influence on the operation of the power plant: bursting of gas containers on the neighbouring roads and railways, fires of all types of hydrocarbons, air pollution through chloride gas, etc. The check by ENSI of the KKN studies on the potential danger for the power plant through neighbouring industrial plants, roads or railways demonstrated that none of the considered accidents presents an unacceptable risk for the power plant: on the one hand, these plants are located too far from the power plant, so that a sensible injury to the power plant safety can be excluded; on the other, the protection of the power plant can be guaranteed through appropriate technical

  15. Die Pluralbildung im Deutschen - ein Versuch im Rahmen der Optimalitätstheorie

    Directory of Open Access Journals (Sweden)

    Wegener, Heide

    1999-01-01

    Full Text Available Die Pluralbildung im Deutschen ist nicht chaotisch, aber komplex. Unabhängig davon, ob man für die Pluralbildung Regeln, Schemata oder die Wortstruktur als Erklärungsmodell benutzt, bleibt die Tatsache einer beachtlichen Zahl miteinander konkurrierender Formen zu erklären. Dies gilt schon deshalb, weil die Variation unter den Pluralformen wohl mit dazu beiträgt, dass trotz der Arbeiten von Mugdan 1977 und Köpcke 1987, 1993, der klaren Darstellung des Pluralsystems in vielen Grammatiken, z.B. Eisenberg 1986, 1989, 1998 noch immer bisweilen die Meinung besteht, die Pluralbildung im Deutschen sei arbiträr.Es soll gezeigt werden, dass das Pluralsystem des Deutschen nach Beschränkungen aufgebaut ist, die morphologischer und silbenphonologischer Natur sind und sich im Rahmen der Optimalitätstheorie (OT beschreiben lassen. Die OT nimmt an, dass Wortformen universalen Beschränkungen (Constraints unterliegen, und dass diese prinzipiell verletzbar sind. Ich werde zunächst die für die Pluralbildung relevanten Beschränkungen definieren, dann an heimischen Pluralformen und -varianten ihr Zusammenwirken zeigen und schließlich den Assimilationsprozess von Fremdwörtern mit Hilfe dieser Beschränkungen und der Beschränkungshierarchien zu erklären versuchen. Daran werden schließlich Überlegungen zu Verarbeitung und Lernbarkeit der Pluralformen geknüpft.

  16. Implantate im Mittelohrbereich - Teil 2 (Ergänzungen 2007)

    Science.gov (United States)

    Stieve, M.; Lenarz, Thomas

    In Deutschland leben ca. 12 Millionen Menschen, die an einer ein- oder beidseitigen Schwerhörigkeit leiden. Diese kann angeboren oder im Laufe des Lebens erworben sein. Klinisch und therapeutisch wichtig ist die Unterscheidung hinsichtlich des Schädigungsortes im Bereich des Mittelohres, d. h. eine Schalleitungsschwerhörigkeit, oder im Bereich des Innenohres, d. h. eine Schallempfindungsschwerhörigkeit, wobei hier der Schädigungsort auch am Hörnerven oder in den zentralen Hörabschnitten liegen kann. Therapeutisch lassen sich sowohl Schwerhörigkeiten im Bereich des Mittelohres als auch im Innenohr und sogar im Hirnstammbereich (Hirnstammimplantat) behandeln. 1,9 Millionen Schwerhörige haben eine Erkrankung im Mittelohrbereich, d. h. der Schall kann nur ungenügend auf das Innenohr übertragen werden. Die Ursache besteht meist in einer chronischen Mittelohrentzündung, die zu einer Zerstörung des Trommelfells und der Gehörknöchelchenkette geführt haben. Therapeutisch und damit als Prinzip der operativen Hörverbesserung steht primär der Verschluß des Trommelfells oder eine Rekonstruktion der Gehörknöchelchen. Mittelohroperationen werden mikrochirurgisch unter dem Operationsmikroskop durchgeführt, wobei zunächst durch eine sanierende Operation der Entzündungsprozeß entfernt wird und nach einer Ausheilungszeit die Gehörknöchelchenkette durch künstliche Prothesen rekonstruiert werden kann.

  17. The twenty-four/four hour ratio (T/F ratio) of Tc-99m MDP uptake in patients with bone metastases and degenerative changes

    International Nuclear Information System (INIS)

    Israel, O.; Kleinhaus, U.; Keren, R.; Frankel, A.; Front, D.

    1984-01-01

    Normal and metastatic bone differ in their histological structure. Normal bone is mainly lamellar while metastatic bone formation is made in a large part out of new woven bone. The woven bone has a much larger surface area than the more stable lamellar bone and it is lined with metabolically active osteoblasts. The crystalline structures in the woven bone are smaller and have a larger surface area available for absorption. Uptake of bone seeking radiopharmaceuticals continues in new woven bone longer than in the lamellar bone. Bone scintigraphy was performed in 89 patients at four hours and 24 hours using a digital camera. The lesion to non lesion (L/N) ratio was determined using the camera computer. The T/F ratio was calculated: T/F=((L/N)-24)/((L/N)-4). Three groups were investigated. In 15 patients with metastatic bone carcinoma, T/F ratio was 1.46 +- 0.4. In 47 patients with degenerative joint disease the T/F ratio was 1.05 +- 0.06. In 27 patients with treated metastatic bone carcinoma the T/F ratio was 1.12 +- 0.13. The T/F ratio is significantly (p<0.001) different in patients with metastases compared to patients with benign degenerative disease. Chemotherapeutic and hormonal treatment cause significant (p<0.001) reduction in the T/F ratio. The T/F ratio may have a potential in differentiating degenerative from neoplastic diseases and in the evaluation of patients with bone metastases undergoing treatment

  18. Inhibition of SARS-CoV 3C-like Protease Activity by Theaflavin-3,3'-digallate (TF3

    Directory of Open Access Journals (Sweden)

    Chia-Nan Chen

    2005-01-01

    Full Text Available SARS-CoV is the causative agent of severe acute respiratory syndrome (SARS. The virally encoded 3C-like protease (3CLPro has been presumed critical for the viral replication of SARS-CoV in infected host cells. In this study, we screened a natural product library consisting of 720 compounds for inhibitory activity against 3CLPro. Two compounds in the library were found to be inhibitive: tannic acid (IC50 = 3 µM and 3-isotheaflavin-3-gallate (TF2B (IC50 = 7 µM. These two compounds belong to a group of natural polyphenols found in tea. We further investigated the 3CLPro-inhibitory activity of extracts from several different types of teas, including green tea, oolong tea, Puer tea and black tea. Our results indicated that extracts from Puer and black tea were more potent than that from green or oolong teas in their inhibitory activities against 3CLPro. Several other known compositions in teas were also evaluated for their activities in inhibiting 3CLPro. We found that caffeine, (—-epigallocatechin gallte (EGCg, epicatechin (EC, theophylline (TP, catechin (C, epicatechin gallate (ECg and epigallocatechin (EGC did not inhibit 3CLPro activity. Only theaflavin-3,3′-digallate (TF3 was found to be a 3CLPro inhibitor. This study has resulted in the identification of new compounds that are effective 3CLPro inhibitors.

  19. Medienerziehung im Vorschulbereich - Zum Projekt Mediengarten der Wiener Medienpädagogik

    Directory of Open Access Journals (Sweden)

    Gudrun Kern

    2010-09-01

    Full Text Available Im Zuge des Projekts Mediengarten der Wiener Medienpädagogik wurde in Kooperation mit angehenden KindergartenpädagogInnen eine Medienerziehung im Sinne einer Auseinandersetzung über Medien im Vorschulbereich anhand konkreter Angebote in Kindergärten konzipiert. Im folgenden Artikel werden die Schwerpunktsetzungen dieses Konzepts vorgestellt und durch praktische Beispiele verdeutlicht.

  20. A Management Tool for Improvement (Improving) IMS Stations Performance

    International Nuclear Information System (INIS)

    Mohammad, D.; Pantin, A.; Quintana, E.

    2011-01-01

    IMS-Maintenance is a software under development by the personnel of ARN-CTBT office, intended for the technical management of IMS stations under ARN's responsibility. This software integrates the whole control of the equipment in an IMS station, including the management of consumables used in daily or periodic operation. It permits an easy retrieval (access) of the technical features, suppliers, etc. of each item of the equipment, as well as its maintenance history and scheduled task. Although this project is still in a starting phase, a preliminary version of this software is being used in radionuclide station RN01 (Buenos Aires), having already demonstrated its usefulness and potential for the improvement of IMS station management. (authors)

  1. Implementing Adaptive Educational Methods with IMS Learning Design

    NARCIS (Netherlands)

    Specht, Marcus; Burgos, Daniel

    2006-01-01

    Please, cite this publication as: Specht, M. & Burgos, D. (2006). Implementing Adaptive Educational Methods with IMS Learning Design. Proceedings of Adaptive Hypermedia. June, Dublin, Ireland. Retrieved June 30th, 2006, from http://dspace.learningnetworks.org

  2. CopperCore, an Open Source IMS Learning Design Engine

    NARCIS (Netherlands)

    Vogten, Hubert

    2004-01-01

    The presentation gives an overview of the approach of the development programme of the OTEC department towards the development of Open Source. The CopperCore IMS Learning Design engine is described as an example of this approach.

  3. [Preussen und Livland im Zeichen der Reformation] / Anti Selart

    Index Scriptorium Estoniae

    Selart, Anti, 1973-

    2015-01-01

    Arvustus: Preussen und Livland im Zeichen der Reformation. Hrsg. von Arno Mentzel-Reuters und Klaus Neitmann. (Tagungsberichte der Historischen Kommission für ost- und westpreussische Landesforschung, 28). Fibre Verlag. Osnabrück 2014

  4. Quantensprung Digitalisierung - Energiewirtschaft im 21. Jahrhundert

    Science.gov (United States)

    Thyen, Elmar

    Die Energiewende wird ohne eine umfassende Digitalisierung der Energiewirtschaft Stückwerk bleiben. Die historisch gewachsene, aus hunderten fossilen Großkraftwerken getriebene Energieversorgung hat sich durch den Zubau von mehr als einer Millionen dezentraler Erzeugungseinheiten innerhalb der vergangenen 15 Jahren radikal verändert. Zum Ausgleich von Last und Erzeugung, aber auch zum Aufbau neuer Geschäftsfelder ist die digitale Technik unverzichtbar. Ihre Möglichkeiten scheinen nahezu unbegrenzt, ihre Rolle wird in einer zukünftig nahezu vollständig elektrifizierten Gesellschaft zunehmend wichtiger werden. Neue Anbieter drängen auf den Markt und setzen die traditionelle Energiewirtschaft unter Druck. Energieversorger, die sich dem Wandel nicht stellen, drohen den Anschluss zu verpassen. Noch werden Verbundunternehmen und Stadtwerke von weitreichenden regulatorischen Vorgaben geschützt. Beispiele aus anderen Branchen zeigen aber, dass die Digitalisierung im Stande ist, regulatorische Mechanismen außer Kraft zu setzen. Zugleich verhindert die enge Regulierung und ein falsch verstandener Datenschutzbegriff in Deutschland die Entwicklung neuer Geschäftsmodelle, die energie- und volkswirtschaftlich sinnvoll wären.

  5. Travestie im alten Ägypten

    Directory of Open Access Journals (Sweden)

    prof.Magda Abdalla

    2011-01-01

    Full Text Available Der Artikel möchte versuchen zu beweisen, dass den alten Ägyptern Travestie bekannt war. In verschiedenen Texten wie Märchen, Fabeln und Liebesgedichten auf Papyri und Ostraka, finden sich Belege von Travestie. Zuerst muss jedoch betont werden, dass es einen Unterschied zwischen dem Begriff der Travestie, mit anderen Worten der Verkleidung,[1] und dem der Metamorphose, dem Verwandeln der Gestalt,[2] gibt. [1] Tra.ve´stie: f. satirisch, Verspottung eines Literaturwerkes, bei der (im Unterschied zur Parodie der Inhalt beibehalten und die Form verändert wird (frz. travestie „Verkleidung“; zu lat. trans „hinüber“+vestire, „kleiden“. G. Wahrig,. Deutsches Wörterbuch, mit einem „Lexikon der deutschen Sprachlehre“( München, 1987, 1292. Es gibt auch eine moderne Definition des Begriffes Travestie aus dem 17. Jahrhundert. Hier beinhaltet diese ein Verfahren oder eine kritische Zielsetzung.w.Karrer.,Parodie Travestie, Pastiche (München, 1977, 19, 46. [2] Me.ta.mor´pho.se Umwandlung eines Gesteins in ein anderes; Wandlung des jungen Tieres durch verschiedene äußere Stadien; Verwandlung von Menschen in Tiere, Pflanzen, Quellen usw. (Deutsches Wörterbuch, 883. الإحصائيات

  6. Das Problem der Ethnogenese im antiken Griechenland

    Directory of Open Access Journals (Sweden)

    Welwei Karl-Wilhelm

    2011-01-01

    Full Text Available Sprachwissenschaftliche Untersuchungen lassen darauf schließen, dass die historischen Dialekte der alten Hellenen erst auf griechischem Boden um und nach 1000 v. Chr. entstanden sind. Bei den frühen Zuwanderern kann es sich nur um kleinere Verbände gehandelt haben, so daß zweifelllos keine großen „Stämme“ nach Griechenland vorgedrungen sind, wie man in der älteren Forschung angenommen hat. In Griechenland haben die Zuwanderer die Suffixe -ss und -nth oder -nd nicht erst kennengelernt, sondern zumindest zum Teil schon mitgebracht und vermutlich im 3. Jahrtausend v. Chr. die allmähliche Entwicklung des späteren Griechischen eingeleitet. Impulse für die Entwicklung der materiellen Kultur gingen um 1700 v. Chr. von Kreta aus und beeinflussten in starkem Maße die mykenische Zeit mit ihren Palastsystemen, deren Zusammenbruch um 1200 v. Chr. aber nicht schon zum Ende der mykenischen Kultur führte, wenn auch die Linear B-Schrift nicht mehr benutzt wurde und die Infrastrukturen der Machtzentren zusammenbrachen. Dies war zugleich die Voraussetzung für die Bildung kleinerer Siedlungen mit neuen Führungssystemen und Sozialstrukturen sowie mit einem jeweils eigenen Identitätsbewußtsein.

  7. CORPORATIVE MOTIVES ON IMPLEMENTATION OF INTEGRATED MANAGEMENT SYSTEM (IMS

    Directory of Open Access Journals (Sweden)

    Dragan Rajkovic

    2009-09-01

    Full Text Available Integration of management systems for quality, environment, health and risk management as well as corporative social responsibilities is workable corporative approach to reduce costs, effective use of resources, higher motivation of employees and better fulfillment of requirements of social engagements and stakeholders. This paper presents contents of literature and review of a company motives on integrated management system (IMS implementation, namely factors affecting the IMS implementation.

  8. Gruppenbezogene Menschenfeindlichkeit im Sport in Sachsen-Anhalt

    OpenAIRE

    Delto, Hannes; Tzschoppe, Petra

    2016-01-01

    Mit der Querschnittsstudie „Wir und die Anderen – Gruppenbezogene Menschenfeindlichkeit im organisierten Sport in Sachsen-Anhalt“ wurde das Syndrom Gruppenbezogener Menschenfeindlichkeit im organisierten Sport untersucht. Das Konzept der Gruppenbezogenen Menschenfeindlichkeit – ausgehend von einer Ideologie der Ungleichwertigkeit – wurde von Prof. Wilhelm Heitmeyer (Universität Bielefeld) entwickelt. Die Ergebnisse ermöglichen explizite Aussagen über Ausmaß und Ursachen Gruppenbezogener Mensc...

  9. Ein Ausblick auf Supply-Chain-Management im Jahr 2016

    DEFF Research Database (Denmark)

    Wieland, Andreas

    2016-01-01

    Wie sieht Supply-Chain-Management im Jahr 2016 aus? Was erwartet uns? Vieles deutet darauf hin, dass SCM in Zukunft sogar noch mehr auf den Kunden gerichtet sein könnte als bisher.......Wie sieht Supply-Chain-Management im Jahr 2016 aus? Was erwartet uns? Vieles deutet darauf hin, dass SCM in Zukunft sogar noch mehr auf den Kunden gerichtet sein könnte als bisher....

  10. Wir und die Anderen: Gruppenbezogene Menschenfeindlichkeit im Sport in Sachsen

    OpenAIRE

    Delto, Hannes; Tzschoppe, Petra

    2015-01-01

    Mit der Querschnittsstudie "Wir und die Anderen – Gruppenbezogene Menschenfeindlichkeit im organisierten Sport in Sachsen" wurde erstmals das Syndrom Gruppenbezogener Menschenfeindlichkeit im organisierten Sport untersucht. Das Konzept der Gruppenbezogenen Menschenfeindlichkeit – ausgehend von einer Ideologie der Ungleichwertigkeit – wurde von Prof. Wilhelm Heitmeyer (Universität Bielefeld) entwickelt. Die Ergebnisse ermöglichen explizite Aussagen über Ausmaß und Ursachen Gruppenbezogener Men...

  11. Eisengehalt von Fleisch - Ermittlung des Eisengehalts im Fleisch verschiedener Tierarten

    OpenAIRE

    Westphal, Karsten; Klose, Ralf; Golze, Manfred

    2009-01-01

    Der Bericht beinhaltet Ergebnisse von Fleischuntersuchungen auf den Eisengehalt. Untersucht wurden 308 Schweinefleischproben und etwa 300 Fleischproben der Tierarten Rind, Bison, Auerochse, Büffel, Schaf, Ziege, Kaninchen, Wildschwein, Rehwild, Rotwild und Fasan. Die sächsischen Ergebnisse bestätigen Untersuchungen anderer Bundesländer und belegen den starken Rückgang des Eisengehaltes im Schweinefleisch. Er lag im Mittel bei 4,1 mg/kg Frischmasse (FM). Vor 30 Jahren lag der Eisengehalt...

  12. Die Raumdarstellung im erzählenden Werk um 1900

    OpenAIRE

    Lu, Xiaoli

    2011-01-01

    In der Literatur existiert eine eigene Welt, die mit Raum und Zeit verbunden ist. Im 19. Jahrhundert gewinnen beide, Raum und Zeit, an Bedeutung als bewusst eingesetzte Gestaltungselemente. Es bilden sich zwei Grundrichtungen heraus, eine mit dem Erzählgeschehen verknüpfte Semantisierung in der Klassik und in der Romantik und eine betonte Fixierung des Geschehens in der realen Welt durch genaue Zeit- und Ortsangaben im Realismus. Die Semantisierung von Raum und Zeit führt zu einer Bedeutungss...

  13. ifo Konjunkturprognose 2015/2016: Deutsche Wirtschaft im Aufschwung

    OpenAIRE

    Wollmershäuser, Timo; Nierhaus, Wolfgang; Berg, Tim Oliver; Breuer, Christian; Garnitz, Johanna; Grimme, Christian; Henzel, Steffen; Hristov, Atanas; Hristov, Nikolay; Meister, Wolfgang; Schröter, Felix; Steiner, Andreas; Wieland, Elisabeth; Wohlrabe, Klaus; Wolf, Anna

    2015-01-01

    Die deutsche Wirtschaft befindet sich derzeit in einem kräftigen Aufschwung. Das reale Bruttoinlandsprodukt wird in diesem Jahr voraussichtlich um 1,9% expandieren und im kommenden Jahr um 1,8%. Der private Konsum bleibt die Stütze des Aufschwungs, da die Einkommensperspektiven der privaten Haushalte aufgrund der sich weiter verbessernden Arbeitsmarktlage gut sind. Allerdings entfallen allmählich die Kaufkraftgewinne durch den Ölpreisrückgang, so dass sich die Konsumdynamik im Prognosezeitrau...

  14. Targeted delivery of siRNA to activated T cells via transferrin-polyethylenimine (Tf-PEI) as a potential therapy of asthma.

    Science.gov (United States)

    Xie, Yuran; Kim, Na Hyung; Nadithe, Venkatareddy; Schalk, Dana; Thakur, Archana; Kılıç, Ayşe; Lum, Lawrence G; Bassett, David J P; Merkel, Olivia M

    2016-05-10

    Asthma is a worldwide health problem. Activated T cells (ATCs) in the lung, particularly T helper 2 cells (Th2), are strongly associated with inducing airway inflammatory responses and chemoattraction of inflammatory cells in asthma. Small interfering RNA (siRNA) as a promising anti-sense molecule can specifically silence inflammation related genes in ATCs, however, lack of safe and efficient siRNA delivery systems limits the application of siRNA as a therapeutic molecule in asthma. Here, we designed a novel pulmonary delivery system of siRNA, transferrin-polyethylenimine (Tf-PEI), to selectively deliver siRNA to ATCs in the lung. Tf-PEI polyplexes demonstrated optimal physicochemical properties such as size, distribution, zeta-potential, and siRNA condensation efficiency. Moreover, in vitro studies showed significantly enhanced cellular uptake and gene knockdown mediated by Tf-PEI polyplexes in human primary ATCs. Biodistribution of polyplexes in a murine asthmatic model confirmed that Tf-PEI polyplexes can efficiently and selectively deliver siRNA to ATCs. In conclusion, the present work proves the feasibility to target ATCs in asthma via Tf receptor. This strategy could potentially be used to design an efficient siRNA delivery system for asthma therapy. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Quantitative comparison of MiTF, Melan-A, HMB-45 and Mel-5 in solar lentigines and melanoma in situ.

    Science.gov (United States)

    Kim, Jinah; Taube, Janis M; McCalmont, Timothy H; Glusac, Earl J

    2011-10-01

    It is often challenging to reliably assess the number of lesional melanocytes in intraepidermal melanocytic proliferations involving sun-damaged skin. Therefore, dermatopathologists routinely use immunostains to help differentiate melanocytes from surrounding keratinocytes. Forty-three cases of solar lentigo or melanoma in situ (of the lentigo maligna type) were retrospectively chosen (20 melanomas in situ and 23 solar lentigo). Microphthalmia transcription factor (MiTF), HMB-45, Melan-A and Mel-5 immunostains were performed with an Azure blue counterstain, and the mean melanocyte counts were calculated within a 1-mm segment of epidermis. In solar lentigines, the mean melanocyte counts were 27 (MiTF), 23 (HMB-45 and Mel-5) and 41 (Melan-A), as compared to hematoxylin and eosin (H&E) (25). In melanoma in situ, the mean melanocyte counts were 112 (MiTF), 149 (Melan-A), 111 (HMB-45) and 80 (Mel-5), as compared to H&E (109). These results show that Melan-A significantly overestimates the density of melanocytes within dermatoheliotic skin. Compared to other tested stains, nuclear staining MiTF allowed greater distinction of melanocytes from keratinocytes with melanized cytoplasm. These findings indicate that MiTF is a superior marker for quantification of melanocytes in the evaluation of subtle intraepidermal melanocytic proliferations and in the differential diagnosis of solar lentigo. Copyright © 2011 John Wiley & Sons A/S.

  16. Coherent ambient infrasound recorded by the global IMS network

    Science.gov (United States)

    Matoza, R. S.; Landes, M.; Le Pichon, A.; Ceranna, L.; Brown, D.

    2011-12-01

    The International Monitoring System (IMS) includes a global network of infrasound arrays, which is designed to detect atmospheric nuclear explosions anywhere on the planet. The infrasound network also has potential application in detection of natural hazards such as large volcanic explosions and severe weather. Ambient noise recorded by the network includes incoherent wind noise and coherent infrasound. We present a statistical analysis of coherent infrasound recorded by the IMS network. We have applied broadband (0.01 to 5 Hz) array processing systematically to the multi-year IMS historical dataset (2005-present) using an implementation of the Progressive Multi-Channel Correlation (PMCC) algorithm in log-frequency space. We show that IMS arrays consistently record coherent ambient infrasound across the broad frequency range from 0.01 to 5 Hz when wind-noise levels permit. Multi-year averaging of PMCC detection bulletins emphasizes continuous signals such as oceanic microbaroms, as well as persistent transient signals such as repetitive volcanic, surf, or anthropogenic activity (e.g., mining or industrial activity). While many of these continuous or repetitive signals are of interest in their own right, they may dominate IMS array detection bulletins and obscure or complicate detection of specific signals of interest. The new PMCC detection bulletins have numerous further applications, including in volcano and microbarom studies, and in IMS data quality assessment.

  17. Grundlegende Steuerungsverfahren im heterogenen Logistiknetz mit Kanban

    Science.gov (United States)

    Dickmann, Eva; Dickmann, Philipp; Lödding, Hermann; Möller, Niklas; Rücker, Thomas; Schneider, Herfried M.; Zäh, Michael F.

    In vielen Unternehmen werden heterogene (verschiedene) Steuerungen in einem abgestimmten Konzept kombiniert. Je nach Anwendungsfall und Rahmenbedingungen werden Kombinationen allgemein bekannter Steuerungen oder Steuerungsvarianten gemischt eingesetzt, um eine optimale Steuerung für unterschiedliche Fälle zu erreichen. Hierbei stehen neben den bekannten und weit verbreiteten Methoden, wie Material Requirements Planning (MRP) oder Kanban, auch weniger bekannte oder neue Methoden zur Auswahl, wie die Produktionssteuerung mit dezentraler, bestandsorientierter Fertigungsregelung (DBF). Kanban ist ein simples und effizientes Steuerungskonzept, das in der klassischen Form für spezifische einfache Anwendungsfälle umsetzbar ist. Hochentwickelte Steuerungsalgorithmen können helfen, komplexe Abläufe optimal abzubilden. Mit einer grundlegenden Vereinfachung der Abläufe kann allerdings in vielen Fällen ein wesentlich stärkerer und umfassender Verbesserungseffekt erzielt werden. Die wesentliche Fragestellung sollte folglich lauten: Warum ist der Ablauf nicht mit einer einfachen Steuerung wie Kanban abzubilden? Um die Vorteile des Konzepts auch in untypischen Bereichen anwenden zu können, sind jedoch verschiedene Varianten oder Kanban-ähnliche Steuerungsmethoden entstanden. Darüber hinaus sind in der Praxis hybride Steuerungen im Einsatz, welche so kombiniert werden, dass die Zusammensetzung anspruchsvolle Eigenschaftsbilder noch exakt abbildet. In der Praxis basieren die Steuerungsentscheidungen nur zu einem kleinen Teil auf den eigentlichen Steuerungsalgorithmen, wie sie uns das MRP-System zur Verfügung stellt. Moderne Steuerungswelten" schließen alle relevanten Informationsquellen in eine heterogene Entscheidungsmatrix mit ein. Letztlich zählt nicht, ob die Entscheidung auf den Informationen aus dem MRP-System oder auf Softfacts basierend getroffen wurde, sondern nur, ob die Entscheidung erfolgreich war.

  18. Structural modelling and molecular dynamics of a multi-stress responsive WRKY TF-DNA complex towards elucidating its role in stress signalling mechanisms in chickpea.

    Science.gov (United States)

    Konda, Aravind Kumar; Farmer, Rohit; Soren, Khela Ram; P S, Shanmugavadivel; Setti, Aravind

    2017-07-28

    Chickpea is a premier food legume crop with high nutritional quality and attains prime importance in the current era of 795 million people being undernourished worldwide. Chickpea production encounters setbacks due to various stresses and understanding the role of key transcription factors (TFs) involved in multiple stresses becomes inevitable. We have recently identified a multi-stress responsive WRKY TF in chickpea. The present study was conducted to predict the structure of WRKY TF to identify the DNA-interacting residues and decipher DNA-protein interactions. Comparative modelling approach produced 3D model of the WRKY TF with good stereochemistry, local/global quality and further revealed W19, R20, K21, and Y22 motifs within a vicinity of 5 Å to the DNA amongst R18, G23, Q24, K25, Y36, Y37, R38 and K47 and these positions were equivalent to the 2LEX WRKY domain of Arabidopsis. Molecular simulations analysis of reference protein -PDB ID 2LEX, along with Car-WRKY TF modelled structure with the DNA coordinates derived from PDB ID 2LEX and docked using HADDOCK were executed. Root Mean Square (RMS) Deviation and RMS Fluctuation values yielded consistently stable trajectories over 50 ns simulation. Strengthening the obtained results, neither radius of gyration, distance and total energy showed any signs of DNA-WRKY complex falling apart nor any significant dissociation event over 50 ns run. Therefore, the study provides first insights into the structural properties of multi-stress responsive WRKY TF-DNA complex in chickpea, enabling genome wide identification of TF binding sites and thereby deciphers their gene regulatory networks.

  19. Turbulent transport and shear at the E x B velocity in wall plasma of the TF-2 tokamak

    International Nuclear Information System (INIS)

    Budaev, V.P.

    1999-01-01

    Turbulence of near-the-wall plasma and potentialities of affecting the turbulence and periphery transport of the TF-2 tokamak by inducing radial electric fields and ergodization of periphery magnetic structure have been investigated, the results are presented. Essential role of the E x B velocity shear in suppression of the turbulence and turbulent transport in periphery has been pointed out. Decrease in transport losses stemming from effect of radial electric fields is brought about suppression of turbulence amplitude, decrease in correlations and decrease in the width of the wave numbers spectrum. Profiles of plasma density, electron temperature, turbulence level, electric fields over entire periphery of discharge change as a result. Ergodization of magnetic structure also results in the change of properties of periphery turbulence and turbulent transport [ru

  20. Qualification and preparatory activities for the manufacturing of 9 TF coils of the JT-60SA magnet

    International Nuclear Information System (INIS)

    Cucchiaro, Antonio; Polli, Gian Mario; Cocilovo, Valter; Drago, Giovanni; Cuneo, Stefano; Terzi, Franco; Peyrot, Marc; Phillips, Guy; Tomarchio, Valerio

    2013-01-01

    In the framework of the Broader Approach Agreement for the construction of the JT-60SA tokamak, ENEA is in charge to provide 9 of the 18 Toroidal Field (TF) coils. The 9 coils are being manufactured by ASG superconductors in Genoa under the supervision of ENEA in collaboration with the JT-60SA European home team. Prior the manufacturing, a preparatory activity has been carried out aimed at designing, constructing and setting-up the relevant components to be realized. In order to get confidence of some special manufacturing process, several qualification activities have been performed. In this paper an overview of the principal milestones reached during the preparatory phase and a description of the qualification activities with relevant test results are presented

  1. Integration of Genome-Wide TF Binding and Gene Expression Data to Characterize Gene Regulatory Networks in Plant Development.

    Science.gov (United States)

    Chen, Dijun; Kaufmann, Kerstin

    2017-01-01

    Key transcription factors (TFs) controlling the morphogenesis of flowers and leaves have been identified in the model plant Arabidopsis thaliana. Recent genome-wide approaches based on chromatin immunoprecipitation (ChIP) followed by high-throughput DNA sequencing (ChIP-seq) enable systematic identification of genome-wide TF binding sites (TFBSs) of these regulators. Here, we describe a computational pipeline for analyzing ChIP-seq data to identify TFBSs and to characterize gene regulatory networks (GRNs) with applications to the regulatory studies of flower development. In particular, we provide step-by-step instructions on how to download, analyze, visualize, and integrate genome-wide data in order to construct GRNs for beginners of bioinformatics. The practical guide presented here is ready to apply to other similar ChIP-seq datasets to characterize GRNs of interest.

  2. The development of engineered safeguards for nuclear power plants in the political and technical environment in the Federal Republic of Germany since 1955; Die Entwicklung der Sicherheitstechnik fuer Kernkraftwerke im politischen und technischen Umfeld der Bundesrepublik Deutschland seit dem Jahr 1955

    Energy Technology Data Exchange (ETDEWEB)

    Laufs, P. [Stuttgart Univ. (Germany). Philosophische-Historische Fakultaet

    2007-01-15

    The safety of nuclear power plants is determined largely by the integrity of the internally pressurized coolant containment system. The highly radioactive materials (fission products) generated within this pressurized containment (primary system) in the reactor core during nuclear power plant operation constitute an extremely great potential hazard. Catastrophic failure of the primary system, and the release into the environment of the radioactive inventory, must be avoided at all costs. Because of the high coolant pressure and the high power density, pressurized water reactors (PWR) impose particularly strict requirements with respect to reactor safety. German nuclear power plants equipped with light water reactors enjoy the reputation of being among the safest plants in the world. This frequent statement is justified in the light of the research and development work performed jointly by industry, government agencies, science, and expert bodies between the 1960s and the 1990s. The research projects, which implied considerable financial expenditures, their internationally acknowledged results, and the resultant additional backfitting measures conducted in German nuclear power plants at many billions of expenditures, were hardly noticed by the German body politic. (orig.)

  3. Genome-wide association study identifies TF as a significant modifier gene of iron metabolism in HFE hemochromatosis.

    Science.gov (United States)

    de Tayrac, Marie; Roth, Marie-Paule; Jouanolle, Anne-Marie; Coppin, Hélène; le Gac, Gérald; Piperno, Alberto; Férec, Claude; Pelucchi, Sara; Scotet, Virginie; Bardou-Jacquet, Edouard; Ropert, Martine; Bouvet, Régis; Génin, Emmanuelle; Mosser, Jean; Deugnier, Yves

    2015-03-01

    Hereditary hemochromatosis (HH) is the most common form of genetic iron loading disease. It is mainly related to the homozygous C282Y/C282Y mutation in the HFE gene that is, however, a necessary but not a sufficient condition to develop clinical and even biochemical HH. This suggests that modifier genes are likely involved in the expressivity of the disease. Our aim was to identify such modifier genes. We performed a genome-wide association study (GWAS) using DNA collected from 474 unrelated C282Y homozygotes. Associations were examined for both quantitative iron burden indices and clinical outcomes with 534,213 single nucleotide polymorphisms (SNP) genotypes, with replication analyses in an independent sample of 748 C282Y homozygotes from four different European centres. One SNP met genome-wide statistical significance for association with transferrin concentration (rs3811647, GWAS p value of 7×10(-9) and replication p value of 5×10(-13)). This SNP, located within intron 11 of the TF gene, had a pleiotropic effect on serum iron (GWAS p value of 4.9×10(-6) and replication p value of 3.2×10(-6)). Both serum transferrin and iron levels were associated with serum ferritin levels, amount of iron removed and global clinical stage (pHFE-associated HH (HFE-HH) patients, identified the rs3811647 polymorphism in the TF gene as the only SNP significantly associated with iron metabolism through serum transferrin and iron levels. Because these two outcomes were clearly associated with the biochemical and clinical expression of the disease, an indirect link between the rs3811647 polymorphism and the phenotypic presentation of HFE-HH is likely. Copyright © 2014 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

  4. High-Pressure Phase Equilibria in Systems Containing CO2 and Ionic Liquid of the [Cnmim][Tf2N] Type

    OpenAIRE

    Sedláková, Z. (Zuzana); Wagner, Z. (Zdeněk)

    2012-01-01

    In this review, we present a comparison of the high-pressure phase behaviour of binary systems constituted of CO2 and ionic liquids of the [Cn(m)mim][Tf2N] type. The comparative study shows that the solubility of CO2 in ionic liquids of the [Cnmim][Tf2N] type generally increases with increasing pressure and decreasing temperature, but some peculiarities have been observed. The solubility of CO2 in ionic liquid solvents was correlated using the Soave–Redlich–Kwong equation of state. The result...

  5. A New IMS Based Inter-working Solution

    Science.gov (United States)

    Zhu, Zhongwen; Brunner, Richard

    With the evolution of third generation network, more and more multimedia services are developed and deployed. Any new service to be deployed in IMS network is required to inter-work with existing Internet communities or legacy terminal users in order to appreciate the end users, who are the main drivers for the service to succeed. The challenge for Inter-working between IMS (IP Multimedia Subsystem) and non-IMS network is “how to handle recipient’s address”. This is because each network has its own routable address schema. For instance, the address for Google Talk user is xmpp:xyz@google.com, which is un-routable in IMS network. Hereafter a new Inter-working (IW) solution between IMS and non-IMS network is proposed for multimedia services that include Instant Messaging, Chat, and File transfer, etc. It is an end-to-end solution built on IMS infrastructure. The Public Service Identity (PSI) defined in 3GPP standard (3rd Generation Partnership Project) is used to allow terminal clients to allocate this IW service. When sending the SIP (Session Initial Protocol) request out for multimedia services, the terminal includes the recipient’s address in the payload instead of the “Request-URI” header. In the network, the proposed solution provides the mapping rules between different networks in MM-IW (Multimedia IW). The detailed technical description and the corresponding use cases are present. The comparison with other alternatives is made. The benefits of the proposed solution are highlighted.

  6. Ion mobility spectrometer / mass spectrometer (IMS-MS).

    Energy Technology Data Exchange (ETDEWEB)

    Hunka Deborah Elaine; Austin, Daniel E.

    2005-07-01

    The use of Ion Mobility Spectrometry (IMS) in the Detection of Contraband Sandia researchers use ion mobility spectrometers for trace chemical detection and analysis in a variety of projects and applications. Products developed in recent years based on IMS-technology include explosives detection personnel portals, the Material Area Access (MAA) checkpoint of the future, an explosives detection vehicle portal, hand-held detection systems such as the Hound and Hound II (all 6400), micro-IMS sensors (1700), ordnance detection (2500), and Fourier Transform IMS technology (8700). The emphasis to date has been on explosives detection, but the detection of chemical agents has also been pursued (8100 and 6400). Combining Ion Mobility Spectrometry (IMS) with Mass Spectrometry (MS) is described. The IMS-MS combination overcomes several limitations present in simple IMS systems. Ion mobility alone is insufficient to identify an unknown chemical agent. Collision cross section, upon which mobility is based, is not sufficiently unique or predictable a priori to be able to make a confident peak assignment unless the compounds present are already identified. Molecular mass, on the other hand, is much more readily interpreted and related to compounds. For a given compound, the molecular mass can be determined using a pocket calculator (or in one's head) while a reasonable value of the cross-section might require hours of computation time. Thus a mass spectrum provides chemical specificity and identity not accessible in the mobility spectrum alone. In addition, several advanced mass spectrometric methods, such as tandem MS, have been extensively developed for the purpose of molecular identification. With an appropriate mass spectrometer connected to an ion mobility spectrometer, these advanced identification methods become available, providing greater characterization capability.

  7. Instrumentale Spielformeln und Vokale Verzierungen im 16.Jahrhundert

    Directory of Open Access Journals (Sweden)

    Göllner, Theodor

    2001-12-01

    Full Text Available In the music of the 16th century, stereotype four-note formulas are found in the instrumental as well as in the vocal idiom. Although frequently identical in appearance, their functions are very different. While indispensable in the instrumental idiom, particularly in keyboard music, where they represent the very essence of instruction in 15th-century organ treatises and fundamenta, they appear in vocal music only as additions to finished compositions or existing practices. What amounts to an absolute necessity in one case is merely an ornamental supplement in the other. In vocal music it is treated as a matter of performance carried out by a qualified soloist and limited to the musical centers of Italy. The present article raises the question as to how the genuinely instrumental and widely spread keyboard practice made its impact on the vocal ornaments of the singer, whose primary concern is the musical communication of language.

    [de] Die in der Musik des 16. Jahrhunderts im Instrumentalen wie im Vokalen vorkommenden, meist viertönigen, stereotypen Formeln sind zwar in beiden Bereichen weitgehend identisch, doch von höchst unterschiedlicher Funktion. Während sie im Instrumentalen, besonders in der Tastenmusik, unverzichtbar sind und schon im 15. Jahrhundert den Kern der Orgeltraktate und Fundamenta bilden, treten sie im Vokalen zu einer fertigen Komposition oder bestehenden Praxis hinzu. Was im einen Fall eine unbedingte Notwendigkeit ist, wird im anderen zu einem nachträglichen Ornament, das sich oft erst bei der Aufftührung einstellt, den qualifizierten Solosänger voraussetzt und auf die musikalischen Zentren Italiens konzentriert war. Der Artikel versucht zu klären, wie sich das genuin instrumentale, allgemein verbreitete Tastenspiel auf die spezielle Verzierungskunst des Sängers auswirkt, dessen primäre Aufgabe es ist, Sprache musikalisch zu vermitteln.

  8. Handover Based IMS Registration Scheme for Next Generation Mobile Networks

    Directory of Open Access Journals (Sweden)

    Shireen Tahira

    2017-01-01

    Full Text Available Next generation mobile networks aim to provide faster speed and more capacity along with energy efficiency to support video streaming and massive data sharing in social and communication networks. In these networks, user equipment has to register with IP Multimedia Subsystem (IMS which promises quality of service to the mobile users that frequently move across different access networks. After each handover caused due to mobility, IMS provides IPSec Security Association establishment and authentication phases. The main issue is that unnecessary reregistration after every handover results in latency and communication overhead. To tackle these issues, this paper presents a lightweight Fast IMS Mobility (FIM registration scheme that avoids unnecessary conventional registration phases such as security associations, authentication, and authorization. FIM maintains a flag to avoid deregistration and sends a subsequent message to provide necessary parameters to IMS servers after mobility. It also handles the change of IP address for user equipment and transferring the security associations from old to new servers. We have validated the performance of FIM by developing a testbed consisting of IMS servers and user equipment. The experimental results demonstrate the performance supremacy of FIM. It reduces media disruption time, number of messages, and packet loss up to 67%, 100%, and 61%, respectively, as compared to preliminaries.

  9. A SURVEY ON INDIAN EXPERIENCE ON INTEGRATED MANAGEMENT STANDARDS (IMS

    Directory of Open Access Journals (Sweden)

    H. Khanna

    2009-09-01

    Full Text Available Adoption of management systems standards is a key issue in manufacturing industry in India. Following the global trend quality and environmental issues are gaining importance. However the number of ISO 14001 certified companies are much less in India as compared to ISO 9001. The integration of ISO 14001 with ISO 9001 may help companies to sustain competitive advantage and overcome disappointments with quality standards and in turn encourage companies to adopt good environmental practices. The aim of this research is to study the implementation of integrated management standards (IMS by the manufacturing organizations in India. The different aspects of integration and benefits of IMS implementation are analyzed. This r esearch is based on empirical study carried out in Indian manufacturing firms, involving the application of a questionnaire. This questionnaire was tested on 50 manufacturing companies in India. The study reveals that focus on stakeholders; top management commitment and training are critical success factors for implementation of IMS. The main benefits of integration are discussed. The small sample size is one of the major limitations of this study. The paper informs the managers in manufacturing organizations and practitioners of management system standards especially in developing countries about IMS and will enable them to adopt IMS in future so that those organizations may not implement multiple and overlapping MSS(Management System Standards.

  10. Transplantate und Implantate im Mittelohrbereich - Teil 1 (Stand 2002)

    Science.gov (United States)

    Kempf, Hans-Georg; Lenarz, Thomas; Eckert, Karl-Ludwig

    In Deutschland leben ungefähr 12 Millionen Menschen, die an einer ein- oder beidseitigen Schwerhörigkeit leiden. Diese kann angeboren oder im Laufe des Lebens erworben sein. Klinisch und therapeutisch wichtig ist die Unterscheidung, ob die Ursache der Schwerhörigkeit im Bereich des Mittelohres, d. h. der Schallübertragung, oder im Bereich des Innenohres, der Hörnerven und der zentralen Hörbahnabschnitte, d. h. der Schallempfindung, liegt. 2,5 Millionen Schwerhörige haben dabei das Problem der Schallübertragung, d.h. die Störung liegt im Mittelohrbereich, und hier kann man in der Regel mit operativen, mikrochirurgisch durchgeführten Massnahmen helfen [1, 2]. Im Vordergrund steht als Ursache hier die chronische Mittelohrentzündung, die sich als Perforation des Trommelfells, als Defekt oder Unterbrechung der Gehörknöchelchen oder auch als Cholesteatom, einer sogenannte Knocheneiterung äussern kann [3]. Therapeutisch und damit als Prinzip der operativen Hörverbesserung steht primär der Verschluss des Trommelfells oder eine Rekonstruktion der Gehörknöchelchen an.

  11. Aggregation und Management von Metadaten im Kontext von Europeana

    Directory of Open Access Journals (Sweden)

    Gerda Koch

    2017-09-01

    Full Text Available Mit dem In-Beziehung-Setzen und Verlinken von Daten im Internet wird der Weg zur Umsetzung des semantischen Webs geebnet. Erst die semantische Verbindung von heterogenen Datenbeständen ermöglicht übergreifende Suchvorgänge und späteres „Machine Learning“. Im Artikel werden die Aktivitäten der Europäischen Digitalen Bibliothek im Bereich des Metadatenmanagements und der semantischen Verlinkung von Daten skizziert. Dabei wird einerseits ein kurzer Überblick zu aktuellen Forschungsschwerpunkten und Umsetzungsstrategien gegeben, und darüber hinaus werden einzelne Projekte und maßgeschneiderte Serviceangebote für naturhistorische Daten, regionale Kultureinrichtungen und Audiosammlungen beschrieben.

  12. Information management system study results. Volume 1: IMS study results

    Science.gov (United States)

    1971-01-01

    The information management system (IMS) special emphasis task was performed as an adjunct to the modular space station study, with the objective of providing extended depth of analysis and design in selected key areas of the information management system. Specific objectives included: (1) in-depth studies of IMS requirements and design approaches; (2) design and fabricate breadboard hardware for demonstration and verification of design concepts; (3) provide a technological base to identify potential design problems and influence long range planning (4) develop hardware and techniques to permit long duration, low cost, manned space operations; (5) support SR&T areas where techniques or equipment are considered inadequate; and (6) permit an overall understanding of the IMS as an integrated component of the space station.

  13. Environmental trace analysis by means of supersensitive GC-IMS

    International Nuclear Information System (INIS)

    Leonhardt, J.W.

    1997-01-01

    The effective control of pollutants in ambient air requires their fast in situ identification and concentration determination of chemical compounds in the range of micrograms per m 3 . There are attempts to use conventional analytical techniques as portable GC and GC-MS. These systems are relatively expensive. A new supersensitive ion Mobility Sensor (IMS) was developed and checked by IUT Ltd, which meets the new demands. The use of tritium sources is an advantage in comparison with other IMS being equipped by nickel-63, the application of which is rather critical in respect of the radiation protection. On the other hand an integrated separation column allows to reduce interferences by matrix effects. The technical parameters of the IUT GC- IMS and some of its most important applications are briefly presented

  14. Wozu und wie kooperative Arbeitsformen im studienbegleitenden Deutschunterricht?

    Directory of Open Access Journals (Sweden)

    Karmelka Barić

    2016-04-01

    Full Text Available Ausgehend von einer Reflexion über die im Beruf und im Leben notwendigen Kompetenzen in der Kommunikation sowie von der Überzeugung, dass es notwendig ist, diese Kompetenzen schon im Studium durch geeignete Arbeitsverfahren und Themen zu entwickeln, werden Kooperation und Autonomie fördernde Arbeitsformen für den studienbegleitenden Deutsch- und Fremdsprachenunterricht (SDU/SFU vorgestellt. Diese Arbeitsformen sind auf andere Sprachen übertragbar und aus dem Lehrwerk Mit Deutsch studieren arbeiten leben A2/B1 (Lévy-Hillerich, Serena, Barić & Cickovska 2010 und der dazu gehörenden Lernplattform entnommen. Das Lehrwerk selbst ist eine Umsetzung der SDU-Rahmencurricula, die im Laufe von über zwanzig Jahren in zehn Ländern im Rahmen eines 1994 am Goethe-Institut Warschau begonnenen Hochschulprojekts und der daraus entstandenen Forschungstätigkeit entstanden sind. Grundlage des Projekts ist ein ganzheitlicher soziopädagogischer Ansatz, der LernerInnen als Menschen betrachtet, die im Präsenz- oder im virtuellen Unterricht in der Sprache und durch die Sprache fach- und sprachübergreifende Kooperationsfähigkeiten entwickeln, die sich später im Leben in der Gesellschaft auswirken. Nach der Vorstellung des Projekts und seiner wissenschaftlichen Hintergründe im ersten Teil des Beitrags werden im zweiten Teil die sich aus dem Ansatz ergebenden Arbeitsformen untersucht: Dabei werden die sich dazu eignenden Themen, die Lernhilfen für StudentInnen, die den LehrerInnen zufallenden Rollen sowie die Ansprüche an Lehrbücher/Unterrichtsmaterialien und Online-/Blended-Learning-Lernszenarien besprochen. Der abschließende Überblick im dritten Teil über die Schwierigkeiten, die beim kooperativen Lernen im SDU/SFU auftreten können, ist gleichzeitig eine offenbleibende Frage danach, wie LehrerInnen aus- und fortgebildet werden sollten, um sich den Anforderungen einer sich dauernd verändernden Lernlandschaft stellen zu können.   The paper

  15. Environmental trace analysis by means of supersensitive GC-IMS

    Energy Technology Data Exchange (ETDEWEB)

    Leonhardt, J.W. [IUTLimited, Berlin, (Germany)

    1997-10-01

    The effective control of pollutants in ambient air requires their fast in situ identification and concentration determination of chemical compounds in the range of micrograms per m{sup 3}. There are attempts to use conventional analytical techniques as portable GC and GC-MS. These systems are relatively expensive. A new supersensitive ion Mobility Sensor (IMS) was developed and checked by IUT Ltd, which meets the new demands. The use of tritium sources is an advantage in comparison with other IMS being equipped by nickel-63, the application of which is rather critical in respect of the radiation protection. On the other hand an integrated separation column allows to reduce interferences by matrix effects. The technical parameters of the IUT GC- IMS and some of its most important applications are briefly presented 6 refs., 1 tab., 5 figs.

  16. Minería de imágenes

    OpenAIRE

    Fernández, Jacqueline; Miranda, Natalia Carolina; Guerrero, Roberto A.; Piccoli, María Fabiana

    2006-01-01

    Durante los últimos años, la proliferación de los medios digitales ha creado la necesidad del desarrollo de herramientas para la eficiente representación, acceso y recuperación de información visual. La minería de imágenes se ha convertido en una importante rama de investigación a causa del potencial que posee en descubrir patrones característicos a partir de un importante conjunto de imágenes. No obstante, la minería de imágenes es más que una simple extensión de la minería de datos al domin...

  17. Treatment processes and demographic variables as predictors of dropout from trauma-focused cognitive behavioral therapy (TF-CBT) for youth.

    Science.gov (United States)

    Yasinski, Carly; Hayes, Adele M; Alpert, Elizabeth; McCauley, Thomas; Ready, C Beth; Webb, Charles; Deblinger, Esther

    2018-05-22

    Premature dropout is a significant concern in trauma-focused psychotherapy for youth. Previous studies have primarily examined pre-treatment demographic and symptom-related predictors of dropout, but few consistent findings have been reported. The current study examined demographic, symptom, and in-session process variables as predictors of dropout from Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) for youth. Participants were a diverse sample of Medicaid-eligible youth (ages 7-17; n = 108) and their nonoffending caregivers (n = 86), who received TF-CBT through an effectiveness study in a community setting. In-session process variables were coded from audio-recorded sessions, and these and pre-treatment demographic variables and symptom levels were examined as predictors of dropout prior to receiving an adequate dose of TF-CBT (parents or relatives. No other demographic or symptom-related factors predicted dropout. These findings highlight the importance of addressing avoidance and therapeutic relationship difficulties in early sessions of TF-CBT to help reduce dropout, and they have implications for improving efforts to disseminate evidence-based trauma-focused treatments. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. TF-finder: A software package for identifying transcription factors involved in biological processes using microarray data and existing knowledge base

    Directory of Open Access Journals (Sweden)

    Cui Xiaoqi

    2010-08-01

    Full Text Available Abstract Background Identification of transcription factors (TFs involved in a biological process is the first step towards a better understanding of the underlying regulatory mechanisms. However, due to the involvement of a large number of genes and complicated interactions in a gene regulatory network (GRN, identification of the TFs involved in a biology process remains to be very challenging. In reality, the recognition of TFs for a given a biological process can be further complicated by the fact that most eukaryotic genomes encode thousands of TFs, which are organized in gene families of various sizes and in many cases with poor sequence conservation except for small conserved domains. This poses a significant challenge for identification of the exact TFs involved or ranking the importance of a set of TFs to a process of interest. Therefore, new methods for recognizing novel TFs are desperately needed. Although a plethora of methods have been developed to infer regulatory genes using microarray data, it is still rare to find the methods that use existing knowledge base in particular the validated genes known to be involved in a process to bait/guide discovery of novel TFs. Such methods can replace the sometimes-arbitrary process of selection of candidate genes for experimental validation and significantly advance our knowledge and understanding of the regulation of a process. Results We developed an automated software package called TF-finder for recognizing TFs involved in a biological process using microarray data and existing knowledge base. TF-finder contains two components, adaptive sparse canonical correlation analysis (ASCCA and enrichment test, for TF recognition. ASCCA uses positive target genes to bait TFS from gene expression data while enrichment test examines the presence of positive TFs in the outcomes from ASCCA. Using microarray data from salt and water stress experiments, we showed TF-finder is very efficient in recognizing

  19. Facebook Ethnography: The Poststructural Ontology of Transnational (Im Migration Research

    Directory of Open Access Journals (Sweden)

    David Joseph Piacenti PhD

    2014-02-01

    Full Text Available This theoretical article discusses the creative utility of Facebook as a new ethnographic tool in which to study transnational (im migration. Facebook ethnography allows the (im migration researcher to transcend the four structural dualities that constrain transnational ethnographic research: (a geographic constraints, (b travel funding constraints, (c travel time constraints, and (d the logistical constraints of entrée into new ethnographic contexts. Facebook ethnography also allows the qualitative researcher to temporarily transcend the ontological structuralist dualities of traditional research methods, producing a new poststructural epistemological and ontological methodology.

  20. IMS IN SMES - REASONS, ADVANTAGES AND BARRIERS ON IMPLEMENTATION

    Directory of Open Access Journals (Sweden)

    Dragan Rajković

    2008-09-01

    Full Text Available Appearance of a number of management systems with various and sometimes divergent demands, demands for revise of optimal strategy on implementation of these standards in small and medium-sized enterprises (SMEs and the attempt on their integration into integrated management system are suggested even more. Firstly question on choice and reasons for implementation of standards is raised. Management and employees expect benefits on the implementation and they pass and minimize the implementation barriers. Basic concept on integrated management system (IMS into SMEs and analyse on reasons, advantages and barriers at IMS implementation are presented in this paper.

  1. Reconocimiento de imágenes utilizando redes neuronales artificiales

    OpenAIRE

    García García, Pedro Pablo

    2013-01-01

    Este trabajo describe el proceso de extracción de patrones característicos de imágenes,mediante la ayuda de Redes Neuronales Artificiales. La información de la Red Neuronal junto con datos adicionales de las imágenes, serán almacenados en una base de datos y consumidos por un servicio web. Un teléfono móvil con sistema operativo Android consumirá la información almacenada en el servicio web. Posteriormente al realizar una captura de imagen con la cámara del teléfono, este procesará la imag...

  2. Frauen im Netz weltweit – ausgegrenzt und mittendrin

    Directory of Open Access Journals (Sweden)

    Sigrid Peuker

    2003-03-01

    Full Text Available Mit dem Global Center for Women’s Studies and Politics (GLOW ist das Feministische Institut der Heinrich-Böll-Stiftung 1998 online gegangen. Mit diesem Schritt wurden Fragen nach den Möglichkeiten und Grenzen sowie nach den Gestaltungsräumen virtueller Kommunikation für Frauen zentral. Mit feminist_spaces. Frauen im Netz. Diskurse – Communities – Visionen, legt die Heinrich-Böll-Stiftung zusammen mit dem Feministischen Institut Antworten aus internationaler Perspektive vor. Das Buch geht auf die gleichnamige zweitätige Konferenz in Berlin im November 2001 zurück.

  3. Hinderniserkennung und -verfolgung mit einer PMD-kamera im automobil

    Science.gov (United States)

    Schamm, Thomas; Vacek, Stefan; Natroshvilli, Koba; Marius Zöllner, J.; Dillmann, Rüdiger

    Die Detektion von Hindernissen vor dem Automobil ist eine Hauptanforderung an moderne Fahrerassistenzsysteme (FAS). In dieser Arbeit wird ein System vorgestellt, das mit Hilfe einer PMDKamera (Photomischdetektor) Hindernisse auf der Fahrspur erkennt und deren relevante Parameter bestimmt. Durch die PMD-Kamera werden zunächst 3D-Tiefenbilder der Fahrzeugumwelt generiert. Nach einem initialen Filterprozess werden im Tiefenbild mit Hilfe eines Bereichswachstumsverfahrens Hindernisse gesucht. Zur Stabilisierung des Verfahrens und zur Parameterberechnung wird ein Kaiman Filter eingesetzt. Das Ergebnis ist eine Liste aller Hindernisse im Fahrbereich des Automobils.

  4. Avaliação do kit "TF-Test" para o diagnóstico das infecções por parasitas gastrintestinais em ovinos

    Directory of Open Access Journals (Sweden)

    Giuliano Lumina

    2006-08-01

    Full Text Available Este estudo teve como objetivos padronizar o kit TF-Test para a quantificação de ovos de parasitas gastrintestinais de ovinos e compará-lo ao método de Gordon & Whitlock modificado (G&W. Vinte quatro cordeiros confinados foram infectados artificialmente com Haemonchus contortus, durante 12 semanas, até o abate, quando foram colhidas amostras fecais e realizada a identificação e contagem dos parasitas abomasais. Nestes animais, ovos de H. contortus foram detectados em 95,8% das amostras fecais por ambos os testes (P>;0,05. Os coeficientes de correlação (r entre a carga parasitária (CP e os valores de OPG obtidos pelos métodos de G&W e TF-Test foram, respectivamente, de r=0,52 e r=0,51 (dados não transformados e r=0,85 e r=0,87 (dados transformados em log. Outras 100 amostras fecais foram colhidas de ovinos naturalmente infectados. Nas amostras destes animais, os testes G&W e TF-Test propiciaram o diagnóstico de ovos de estrongilídeos em 85% e 86% das amostras, respectivamente (P>;0,05. Pelo TF-Test e pelo G&W, oocistos de Eimeria foram detectados em 33% e em 12% das amostras (P<0,001 e ovos de Strongyloides spp. em 15% e 5% das amostras, respectivamente (P<0,05. Ambos os testes foram precisos para o diagnóstico de estrongilídeos gastrintestinais, porém, o TF-Test foi superior para o diagnóstico de oocistos de Eimeria spp. e de ovos de Strongyloides spp., mas, por outro lado, subestimou o número de ovos de estrongilídeos presente nas amostras.

  5. Electroreduction Property and MD Simulation of Nitrobenzene in Ionic Liquid [BMim][Tf2N]/[BMim][BF4

    International Nuclear Information System (INIS)

    Zeng, Jianping; Zhang, Yinxu; Sun, Ruyao; Chen, Song

    2014-01-01

    Highlights: • The two different common accessible ionic liquids are mixed in a simple and economic way. • In some compound ratios, the dynamic performance of nitrobenzene is superior to either of ionic liquids. • Modification and functionalization of ionic liquids in electrochemical field is feasible. • The mass transfer of diffusion of nitrobenzene in ionic liquids can be simulated with molecular dynamics. • Molecular dynamics explains the improvement of nitrobenzene in composite ionic liquids. - Abstract: The two different common accessible ionic liquids [BMim][BF 4 ] and [BMim][Tf 2 N] were mixed each other in a simple and economic way. In some compound ratios, the dynamic performance of nitrobenzene in electric reduction was superior to that of any single kind of ionic liquid has been appeared. The interaction and mass transfer of diffusion of nitrobenzene in composite ionic liquids with different volume ratios were studied with molecular dynamics (MD) simulation. The improvement of the electroreduction performance of nitrobenzene in composite ionic liquids was verified and was tried to explain. This provides a new idea for the modification and functionalization of ionic liquids in electrochemical field. The experimental results showed that kinematic viscosity and electroconductibility of different ionic liquid systems display a regular change. And the change law has been basically unchanged after adding water. The two different functional ionic liquids were complemented each other in a simple and economic way, which has compensated for the disadvantage of mono-component ionic liquids. At 25 °C, electroreduction property of V [BMim][BF4] :V [BMim][Tf2N] = 1:1 is the best in cyclic voltammetry experiments of nitrobenzene in different composite ionic liquids. Its electrochemical behavior is significantly affected by scan rate, temperature, concentration of nitrobenzene and concentration of water. The MD simulation results showed most of interaction

  6. Im Wind / Mari Vallisoo ; tõlk. Gisbert Jänicke

    Index Scriptorium Estoniae

    Vallisoo, Mari, 1950-2013

    2003-01-01

    Sisu: Im Wind = Tuulega ; Zwei Frauen = Kaks naist ; In Gedanken an Aleksander Levin = aleksander Levinile mõteldes ; Jetzt im Dunkel = Nüüd pimedas ; Fragen = Küsimused ; Der Zwillingsbruder = Kaksikvend

  7. Regelungen im Verkehr mit Lebensmitteln und Bedarfsgegenständen in Deutschland

    Science.gov (United States)

    Thomas, Gundula; Freund, Astrid; Gründig, Friedrich

    Im Zuge der Globalisierung von Produktion und Handel ändert sich auch der Charakter der Vorschriften im Lebensmittelrecht. Zunehmend treten internationale Rechtsbestimmungen, Abkommen, Standards und andere Normen an die Stelle nationaler Regelungen.

  8. International Monitoring system (IMS) build-up in Africa: Current status and the way forward

    International Nuclear Information System (INIS)

    Basham, P.

    2002-01-01

    The complete IMS verification system for primary and auxiliary seismic together with that of radionuclide, hydroacoustic and infrasound is plotted on a global map and Africa in particular showing its status. IMS situation in East and Southern Africa is included

  9. Volatility study of [C1C1im][NTf2] and [C2C3im][NTf2] ionic liquids

    International Nuclear Information System (INIS)

    Rocha, Marisa A.A.; Ribeiro, Filipe M.S.; Schröder, Bernd; Coutinho, João A.P.; Santos, Luís M.N.B.F.

    2014-01-01

    Highlights: • Vapor pressures of [C 1 C 1 im][NTf 2 ] and [C 2 C 3 im][NTf 2 ] ionic liquids are reported. • [C 1 C 1 im][NTf 2 ] presents higher enthalpy and entropy of vaporization than expected. • The high volatility of [C 2 C 3 im][NTf 2 ] is a result from its asymmetric character. -- Abstract: Vapor pressures of 1,3-dimethylimidazolium bis(trifluoromethylsulfonyl)imide, ([C 1 C 1 im][NTf 2 ]) and 1-ethyl-3-propylimidazolium bis(trifluoromethylsulfonyl)imide, ([C 2 C 3 im][NTf 2 ]) ionic liquids were measured as a function of temperature using a Knudsen effusion apparatus combined with a quartz crystal microbalance. Enthalpies and entropies of vaporization were derived from the fitting of vapor pressure and temperature results to the Clarke and Glew equation. [C 1 C 1 im][NTf 2 ] presents a higher enthalpy and entropy of vaporization than the neighboring members of the series. The enthalpy of vaporization of [C 2 C 3 im][NTf 2 ] lies in between the asymmetric and symmetric ionic liquid series, reflecting a decrease in the electrostatic interactions due to a decrease of the charge accessibility between the ionic pairs when the methyl group is replaced by an ethyl group. The obtained higher volatility of [C 2 C 3 im][NTf 2 ] arises from its asymmetric character, leading to an higher entropic contribution that compensates the enthalpic penalty. The border conditions ([C 1 C 1 im][NTf 2 ], [C 2 C 1 im][NTf 2 ] and [C 2 C 2 im][NTf 2 ]), topology ([C 2 C 3 im][NTf 2 ]) and symmetry/asymmetry of the ILs effect were evaluated and rationalized based on a comparative analysis of the thermodynamic properties, enthalpies and entropies of vaporization

  10. A two-dimensional, finite-element methods for calculating TF coil response to out-of-plane Lorentz forces

    International Nuclear Information System (INIS)

    Witt, R.J.

    1989-01-01

    Toroidal field (TF) coils in fusion systems are routinely operated at very high magnetic fields. While obtaining the response of the coil to in-plane loads is relatively straightforward, the same is not true for the out-of-plane loads. Previous treatments of the out-of-plane problem have involved large, three-dimensional finite element idealizations. A new treatment of the out-of-plane problem is presented here; the model is two-dimensional in nature, and consumes far less CPU-time than three-dimensional methods. The approach assumes there exists a region of torsional deformation in the inboard leg and a bending region in the outboard leg. It also assumes the outboard part of the coil is attached to a torque frame/cylinder, which experiences primarily torsional deformation. Three-dimensional transition regions exist between the inboard and outboard legs and between the outboard leg and the torque frame. By considering several idealized problems of cylindrical shells subjected to moment distributions, it is shown that the size of these three-dimensional regions is quite small, and that the interaction between the torsional and bending regions can be treated in an equivalent two-dimensional fashion. Equivalent stiffnesses are derived to model penetration into and twist along the cylinders. These stiffnesses are then used in a special substructuring analysis to couple the three regions together. Results from the new method are compared to results from a 3D continuum model. (orig.)

  11. Horizontal stratified flow model for the 1-D module of WCOBRA/TRAC-TF2: modeling and validation

    Energy Technology Data Exchange (ETDEWEB)

    Liao, J.; Frepoli, C.; Ohkawa, K., E-mail: liaoj@westinghouse.com [Westinghouse Electric Company LLC, LOCA Integrated Services I, Cranberry Twp, Pennsylvania (United States)

    2011-07-01

    For a two-phase flow in a horizontal pipe, the individual phases may separate by gravity. This horizontal stratification significantly impacts the interfacial drag, interfacial heat transfer and wall drag of the two phase flow. For a PWR small break LOCA, the horizontal stratification in cold legs is a highly important phenomenon during loop seal clearance, boiloff and recovery periods. The low interfacial drag in the stratified flow directly controls the time period for the loop clearance and the level of residual water in the loop seal. Horizontal stratification in hot legs also impacts the natural circulation stage of a small break LOCA. In addition, the offtake phenomenon and cold leg condensation phenomenon are also affected by the occurrence of horizontal stratification in the cold legs. In the 1-D module of the WCOBRA/TRAC-TF2 computer code, a horizontal stratification criterion was developed by combining the Taitel-Dukler model and the Wallis-Dobson model, which approximates the viscous Kelvin-Helmholtz neutral stability boundary. The objective of this paper is to present the horizontal stratification model implemented in the code and its assessment against relevant data. The adequacy of the horizontal stratification transition criterion is confirmed by examining the code-predicted flow regime in a horizontal pipe with the measured data in the flow regime map. The void fractions (or liquid level) for the horizontal stratified flow in cold leg or hot leg are predicted with a reasonable accuracy. (author)

  12. A study on IP2C actuators using ethylene glycol or EmI-Tf as solvent

    International Nuclear Information System (INIS)

    Di Pasquale, Giovanna; Pollicino, Antonino; Fortuna, Luigi; Graziani, Salvatore; Umana, Elena; La Rosa, Manuela

    2011-01-01

    Ionic polymer–polymer composites (IP 2 Cs) are a novel class of all-organic electroactive polymers that can operate both as electromechanical actuators and as sensors. They are an evolution of ionic polymer–metal composites (IPMCs), since the metallic layers, used to realize the electrodes, are substituted by using organic conductors based on PEDOT:PSS. For the IPMC based actuators it is generally reported that solvents different from water can be used to avoid the dehydration phenomenon. Here the possibility to use ethylene glycol and an ionic liquid, 1-ethyl-3-methylimidazolium trifluoromethanesulfonate, as diluents for the IP 2 C is investigated. Moreover, different materials have been used for the manufacture of the device electrodes and the performances of different organic transducers have been observed and compared. Reported results show that the use of both ethylene glycol and EmI-Tf as the solvent can have beneficial effects both on the working time duration of IP 2 C and on the corresponding transduction behaviors

  13. Analysis of quench-vent pressures for present design of ITER [International Thermonuclear Experimental Reactor] TF [toroidal field] coils

    International Nuclear Information System (INIS)

    Slack, D.S.

    1989-01-01

    The International Thermonuclear Experimental Reactor (ITER) is a new tokamak design project with joint participation from Japan, the European Community, the Union of the Soviet Union, and the United States. This paper examines the effects of a quench within the toroidal field (TF) coils based on current ITER design. It is a preliminary, rough analysis. Its intent is to assist ITER designers while more accurate computer codes are being developed and to provide a check against these more rigorous solutions. Rigorous solutions to the quench problem are very complex involving three-dimensional heat transfer, extreme changes in heat capacities and copper resistivity, and varying flow dynamics within the conductors. This analysis addresses all these factors in an approximate way. The result is much less accurate than a rigorous analysis. Results here could be in error as much as 30 to 40 percent. However, it is believed that this paper can still be very useful to the coil designer. Coil pressures and temperatures vs time into a quench are presented. Rate of helium vent, energy deposition in the coil, and depletion of magnetic stored energy are also presented. Peak pressures are high (about 43 MPa). This is due to the very long vent path length (446 m), small hydraulic diameters, and high current densities associated with ITER's cable-in-conduit design. The effects of these pressures as well as the ability of the coil to be self protecting during a quench are discussed. 3 refs., 3 figs., 1 tab

  14. Peringkasan Tweet Berdasarkan Trending Topic Twitter Dengan Pembobotan TF-IDF dan Single Linkage AngglomerativeHierarchical Clustering

    Directory of Open Access Journals (Sweden)

    Annisa Annisa

    2016-10-01

    Full Text Available Trending topic is a feature provided by twitter that informs something widely discussed by users in a particular time. The form of a trending topic is a hashtag and can be selected by clicking. However, the number of tweets for each trending topics can be very large, so it will be difficult if we want to know all the contents. So, in order to make easy when reading the topic, a small number of tweets can be selected as the main idea of the topic. In this study, we applied the Agglomerative Single Linkage Hierarchical Clustering by calculating the TF-IDF value for each word in advance. We used 100 trending topics, where each topic consists of 50 tweets in Indonesian. For testing, we provided 30 trending topics which consist of 2 until 9 sub-topics. The result is that each trending topics can be summarized into shorter text contains 2 until 9 tweets. We were able to summarize 1 trending topics exactly same as the topic summarized by human expert. However, the rest of topics corresponded partially with human expert.

  15. Validation of special processes for the integration activities of the JT-60SA TF coils manufactured in Italy

    Energy Technology Data Exchange (ETDEWEB)

    Polli, Gian Mario, E-mail: gianmario.polli@enea.it [ENEA, UT-FUS, Via E. Fermi 45, Frascati (Italy); Cucchiaro, Antonio; Cocilovo, Valter [ENEA, UT-FUS, Via E. Fermi 45, Frascati (Italy); Drago, Giovanni; Pesenti, Paolo; Cuneo, Stefano; Terzi, Franco [ASG Superconductors, Corso Perrone 73 r, Genova (Italy); Phillips, Guy; Tomarchio, Valerio [JT-60SA European Home Team, 85748 Garching bei Munchen (Germany)

    2015-10-15

    Highlights: • Insertion. • Casing welding. • Casing embedding. - Abstract: In the framework of the Broader Approach Agreement for the construction of the JT-60SA tokamak, ENEA provides 9 of the 18 toroidal field (TF) coils of the JT-60SA magnet system. The 9 coils are being manufactured by ASG superconductors in Genoa under the supervision of ENEA in collaboration with the JT-60SA European home team. The manufacturing is composed of two main steps: one concerning winding pack assembly and impregnation, and the other devoted to the integration into the casing structure and associated final coil preparation. This paper describes the results of the validation activities set-up for the integration phase. Specifically, welding of casing components has been retained particularly critical for at least three reasons: (i) during welding the WP may be damaged by the intense heating; (ii) distortion caused by heating may determine incorrect coil geometry and then field errors; and (iii) flaws may reduce structural strength and then the overall lifetime of the machine. Similarly, final embedding has been demonstrated on a 1 m long mock-up of the coil. Main results and lessons learned are here described.

  16. Mapping of the Pim-1 oncogene in mouse t-haplotypes and its use to define the relative map positions of the tcl loci t0(t6) and tw12 and the marker tf (tufted).

    Science.gov (United States)

    Ark, B; Gummere, G; Bennett, D; Artzt, K

    1991-06-01

    Pim-1 is an oncogene activated in mouse T-cell lymphomas induced by Moloney and AKR mink cell focus (MCF) viruses. Pim-1 was previously mapped to chromosome 17 by somatic cell hybrids, and subsequently to the region between the hemoglobin alpha-chain pseudogene 4 (Hba-4ps) and the alpha-crystalline gene (Crya-1) by Southern blot analysis of DNA obtained from panels of recombinant inbred strains. We have now mapped Pim-1 more accurately in t-haplotypes by analysis of recombinant t-chromosomes. The recombinants were derived from Tts6tf/t12 parents backcrossed to + tf/ + tf, and scored for recombination between the loci of T and tf. For simplicity all t-complex lethal genes properly named tcl-tx are shortened to tx. The Pim-1 gene was localized 0.6 cM proximal to the tw12 lethal gene, thus placing the Pim-1 gene 5.2 cM distal to the H-2 region in t-haplotypes. Once mapped, the Pim-1 gene was used as a marker for further genetic analysis of t-haplotypes. tw12 is so close to tf that even with a large number of recombinants it was not possible to determine whether it is proximal or distal to tf. Southern blot analysis of DNA from T-tf recombinants with a separation of tw12 and tf indicated that tw12 is proximal to tf. The mapping of two allelic t-lethals, t0 and t6 with respect to tw12 and tf has also been a problem.(ABSTRACT TRUNCATED AT 250 WORDS)

  17. Mapping IMS Learning Design and Moodle. A first understanding

    NARCIS (Netherlands)

    Burgos, Daniel; Tattersall, Colin; Dougiamas, Martin; Vogten, Hubert; Koper, Rob

    2006-01-01

    Please, cite this publication as follows: Burgos, D., Tattersall, C., Dougiamas, M., Vogten, H., & Koper, E. J. R. (2006). Mapping IMS Learning Design and Moodle. A first understanding. Proceedings of Simposo Internacional de Informática Educativa (SIIE06), León, Spain: IEEE Technical Committee on

  18. Collaborative Research: Calibration for IMS Stations in Eastern Asia

    Science.gov (United States)

    2007-07-01

    Atomnaya Energia , Vol.87, Issue 3, 1989 (in Russian). 142 BondAr, I. Combining 1-D models for regional calibration, in Proceedings of a Workshop on IMS...Zelentsov and V.N. Mikhailov, Characteristics of 96 underground nuclear explosions at the Semipalatinsk Test Site, Atomaya Energia , (in Russian), Vol. 67

  19. EFEKTIVITAS MEDIA PEMBELAJARAN IM3 DITINJAU DARI MOTIVASI BELAJAR

    Directory of Open Access Journals (Sweden)

    J. Handhika

    2012-10-01

    Full Text Available Penelitian ini bertujuan untuk mengetahui perbedaan penggunaan media pembelajaran IM3 berbasis flash dan media MS. Power Point terhadap prestasi belajar IPA-Fisika. Hasil penelitian  menunjukkan bahwa siswa yang diajar menggunakan media IM3 berbasis flash memberikan rata-rata prestasi lebih baik dibandingkan dengan siswa yang diajar menggunakan power point. Siswa dengan motivasi belajar tinggi menghasilkan rata-rata prestasi lebih baik daripada siswa dengan motivasi belajar rendah, serta terdapat interaksi motivasi belajar dengan media pembelajaran terhadap prestasi belajar IPA-Fisika.   This study aims to determine differences in the use of flash-based IM3 learning media and MS media. Power Point to IPA-Physics learning achievement. Results showed that students who were taught using flash-based media IM3 gives an average performance better than students who were taught using the power point. Students with high motivation to learn the average yield better performance than students with low learning motivation, and there is interaction with the medium of learning motivation toward science learning achievement-Physics.

  20. Address Translation Problems in IMS Based Next Generation Networks

    Directory of Open Access Journals (Sweden)

    Balazs Godor

    2006-01-01

    Full Text Available The development of packed based multimedia networks reached a turning point when the ITU-T and the ETSIhave incorporated the IMS to the NGN. With the fast development of mobile communication more and more services andcontent are available. In contrast with fix network telephony both the services and the devices are personalized in the “mobileworld”. Services, known from the Internet - like e-mail, chat, browsing, presence, etc. – are already available via mobiledevices as well. The IMS originally wanted to exploit both the benefits of mobile networks and the fancy services of theInternet. But today it is already more than that. IMS is the core of the next generation telecommunication networks and abasis for fix-mobile convergent services. The fact however that IMS was originally a “mobile” standard, where IPv6 was notoddity generated some problems for the fix networks, where IPv4 is used. In this article I give an overview of these problemsand mention some solutions as well.

  1. I'm Positive: Growing Up with Self-Esteem.

    Science.gov (United States)

    Kansas State Univ., Manhattan. Cooperative Extension Service.

    This document presents "I'm Positive: Growing Up With Self-Esteem," an informal, personal study course designed to strengthen the reader's ability to nurture self-esteem in children from birth through adolescence. Special emphasis is given to four parenting skills: acceptance, encouragement, empowerment, and love. Weekly activities are provided…

  2. Sixteenth Meeting of the IMS Study Group "Cantus Planus"

    Czech Academy of Sciences Publication Activity Database

    Vozková, Jana

    2011-01-01

    Roč. 48, 2-3 (2011), s. 310-311 ISSN 0018-7003. [Sixteenth Meeting of the IMS Study Group “Cantus Planus”. Vídeň, 21.08.2011–27.08.2011] Institutional research plan: CEZ:AV0Z90580513 Keywords : plainchant * annual conference * International Musicological Society Subject RIV: AL - Art, Architecture, Cultural Heritage

  3. Ausländische Direktinvestitionen und Technologietransfer im angolanischen Energiesektor

    Directory of Open Access Journals (Sweden)

    2016-04-01

    Full Text Available Dem Zusammenhang von ausländischen Direktinvestionen (Foreign Direct Investment, FDI und Technologietransfer wird sowohl in der Forschung als auch in der politischen Analyse große Bedeutung zugeschrieben. Zahlreiche Veröffentlichungen belegen, dass FDI den Transfer von und/oder den Zugang zu Technologien erleichtert. Allerdings gibt es zu wenige empirische Studien, die diesen Zusammenhang in Bezug auf die Wirtschaft afrikanischer Staaten untersuchen. Der Autor will diese Lücke zu einem kleinen Teil schließen, indem er die Bedeutung des Technologietransfers durch den Zufluss von FDI im Energiesektor Angolas ermittelt. Seine Analyse basiert auf qualitativer Forschung in Angola im Jahr 2014. Er zeigt auf, dass sich die Erzeugung von Energie(trägern und die Verteilungsinfrastruktur - maschinelle Ausrüstung und Qualifizierung - durch den Zufluss von FDI erheblich entwickeln konnte. Allerdings gebe es keinen Beleg dafür, dass dieser Zufluss die endogenen wissenschaftlichen und technologischen Forschungspotenziale im angolanischen Energiesektor gefördert hat. Der Autor empfiehlt politische Maßnahmen zur Förderung dieser Fähigkeiten, insbesondere im Bereich der Produktion.

  4. First inter metatarsal (IM) angles in Nigerians and their relationship ...

    African Journals Online (AJOL)

    Background: No age is immune to the deformity known as Hallux valgus as it has been proven that 50% of adults developed it during adolescence, while 40% of juveniles developed it before the age of 10.5 years. Aim: To determine from radiographs the normal value of the first inter metatarsal (IM) angle and to establish if ...

  5. Using IMS Learning Design to model collaborative learning activities

    NARCIS (Netherlands)

    Tattersall, Colin

    2006-01-01

    IMS Learning Design provides a counter to the trend towards designing for lone-learners reading from screens. It guides staff and educational developers to start not with content, but with learning activities and the achievement of learning objectives. It recognises that learning can happen without

  6. MATTHEW'S SITZ IM LEBEN AND THE EMPHASIS ON THE TORAH

    African Journals Online (AJOL)

    Acta Theologica ... such as would be expected from letters (Bauckham 1998:48). Yet the ... it in other words; the Sitz im Leben der alten Kirche can indirectly be .... 4 Along with most scholars I assume that Matthew was written some time after.

  7. Distance tracking scheme for seamless handover in IMS-based ...

    African Journals Online (AJOL)

    This paper proposes a fast and seamless handover scheme for systems based on IP Multimedia Subsystem (IMS) architectural framework with Universal Mobile Telecommunications System (UMTS) access network. In the scheme the location, direction and movement pattern of a Mobile Node (MN) in a network cell are ...

  8. Choosing the Right Free IM Providers and Clients for Your Library

    Science.gov (United States)

    Izenstark, Amanda K.

    2009-01-01

    With virtual library services increasing, public services librarians may find themselves with questions such as: What instant messaging services (IM) are available? Which IM service would best suit my patrons' needs? Which IM service best suits my library's technology profile? This column describes the features and functionality of major instant…

  9. Pengaruh Intensitas Mengakses Twitter Duta Im3 terhadap Kepuasan Pengalaman Adopsi dan Kepuasan Pengalaman Adopsi terhadap Keputusan Penggunaan Program Im3

    OpenAIRE

    Ayu Kinasih, Diyan Hafdinovianti; Pradekso, Tandiyo; Setiabudi, Djoko

    2014-01-01

    Nama : Diyan H Ayu KinasihNIM : D2C009029Judul : Pengaruh Intensitas Mengakses Twitter Duta IM3 terhadapKepuasan Pengalaman Adopsi dan Kepuasan PengalamanAdopsi terhadap Keputusan Penggunaan Program IM3ABSTRAKTwitter sebagai salah satu promotion tools yang digunakan oleh PTIndosat Tbk, diharapkan dapat memperkenalkan program-program serta eventyang dilakukan oleh Indosat. Melalui duta IM3 sebagai brand ambassador, Indosatmencoba meraih pasar anak muda dengan melakukan kegiatan promosi.Tipe pe...

  10. Usability test of the ImPRO, computer-based procedure system

    International Nuclear Information System (INIS)

    Jung, Y.; Lee, J.

    2006-01-01

    ImPRO is a computer based procedure in both flowchart and success logic tree. It is evaluated on the basis of computer based procedure guidelines. It satisfies most requirements such as presentations and functionalities. Besides, SGTR has been performed with ImPRO to evaluate reading comprehension and situation awareness. ImPRO is a software engine which can interpret procedure script language, so that ImPRO is reliable by nature and verified with formal method. One bug, however, had hidden one year after release, but it was fixed. Finally backup paper procedures can be prepared on the same format as VDU in case of ImPRO failure. (authors)

  11. Trauma-Focused Early Intensive Cognitive Behavioral Intervention (TF-EICBI) in children and adolescent survivors of suicide bombing attacks (SBAs). A preliminary study.

    Science.gov (United States)

    Leor, Agnes; Dolberg, Orna T; Eshel, Shira Pagorek; Yagil, Yaron; Schreiber, Shaul

    2013-01-01

    To describe and evaluate the impact of an early intervention (Trauma-Focused Early Intensive Cognitive Behavioral Intervention, TF-EICBI) in children and adolescents who were victims of suicide bombing attacks (SBAs) in Israel. Description of an intervention and preliminary experience in its use. An acute trauma center of a Child and Adolescent Psychiatric Unit in a Department of Psychiatry of a university-affiliated medical center. Ten children and adolescents who were victims of SBAs and underwent early interventions (EIG) were compared to 11 adolescent victims who received no intervention (NEIG). The EIG included all the children and adolescent survivors of various SBAs that had occurred during 1 year who presented to our hospital after the TF-EICBI was implemented (June 2001). The NEIG comprised all adolescents girls children and adolescents after SBAs.

  12. Identification of novel mutations in HFE, HFE2, TfR2, and SLC40A1 genes in Chinese patients affected by hereditary hemochromatosis.

    Science.gov (United States)

    Wang, Yongwei; Du, Yali; Liu, Gang; Guo, Shanshan; Hou, Bo; Jiang, Xianyong; Han, Bing; Chang, Yanzhong; Nie, Guangjun

    2017-04-01

    Hereditary hemochromatosis (HH) is a group of inherited iron-overload disorders associated with pathogenic defects in the genes encoding hemochromatosis (HFE), hemojuvelin (HJV/HFE2), hepcidin (HAMP), transferrin receptor 2 (TfR2), and ferroportin (FPN1/SLC40A1) proteins, and the clinical features are well described. However, there have been only a few detailed reports of HH in Chinese populations. Thus, there is insufficient patient information for population-based analyses in Chinese populations or comparative studies among different ethical groups. In the current work, we describe eight Chinese cases of hereditary hemochromatosis. Gene sequencing results revealed eight mutations (five novel mutations) in HFE, HFE2, TfR2, and SLC40A1 genes in these Chinese HH patients. In addition, we used Polymorphism Phenotyping v2 (Polyphen), Sorting Intolerant From Tolerant (SIFT), and a sequence alignment program to predict the molecular consequences of missense mutations.

  13. A digital multi-channel spectroscopy system with 100 MHz flash ADC module for the GENIUS-TF and GENIUS projects

    OpenAIRE

    Kihm, T.; Bobrakov, V. F.; Klapdor-Kleingrothaus, H. V.

    2003-01-01

    In this paper we will present the first results of applying a digital processing technology in low-level gamma spectroscopy with HPGE detectors. An experimental gamma spectrometer using Flash ADC module is built and tested. The test system is now under development and shows major advantages over the traditional analog technologies. It will be installed for the GENIUS-TF and GENIUS projects in Gran-Sasso in early 2003.

  14. Small-angle neutron scattering from the reconstituted TF sub 1 of H sup + -ATPase from thermophilic bacterium PS3 with deuterated subunits

    Energy Technology Data Exchange (ETDEWEB)

    Ito, Yuji [Univ. of Tokyo (Japan) Brookhaven National Lab., Upton, NY (United States); Harada, Mitsuo [Univ. of Tokyo (Japan); Ohta, Shigeo; Kagawa, Yasuo; Aono, Osamu [Jichi Medical School, Tochigi (Japan); Schefer, J; Schoenborn, B P [Brookhaven National Lab., Upton (United States)

    1990-01-01

    Subunits {alpha}, {beta} and {gamma} of adenosine triphosphatase (H{sup +}-ATPase) from the thermophilic bacterium PS3 (TF{sub 1}) have been over-expressed in Escherichia coli. {alpha} and {beta} subunits deuterated to the level of 90% were obtained by culturing E. coli in {sup 2}H{sub 2}O medium. Both the subunits and the reconstituted {alpha}{beta}{gamma} complex, TF{sub 1}, which contain the deuterated components in various combinations, were studied in solution by small-angle neutron scattering. The individual shapes of the subunits and their organization in the {alpha}{beta}{gamma}-TF{sub 1} complex were examined using the techniques of selective deuteration and contrast variation. The {alpha} and {beta} subunits are well approximated as ellipsoids of revolution having minor semi-axes of 20{center dot}4({plus minus}0{center dot}4) and 20{center dot}0({plus minus}0{center dot}2) {angstrom}, and major semi-axes of 53{center dot}0({plus minus}1{center dot}4) and 55{center dot}8({plus minus}0{center dot}9) {angstrom}, respectively. In the TF{sub 1} complex, three {beta} subunits are aligned to form an equilateral triangle, with their major axes tilted by 35{degree} with respect to the 3-fold axis of the complex. The {beta}-{beta} distance is about 53 {angstrom}. Three {alpha} subunits are similarly arranged, positioned between the {beta} subunits, and with their direction of tilt opposite to that of the {beta} subunits. The centers of the {alpha} and {beta} subunits lie in the same plane, forming a hexagon. Adjacent subunits overlap in this model, suggesting that they are not simple ellipsoids of revolution.

  15. A digital multi-channel spectroscopy system with 100 MHz flash ADC module for the GENIUS-TF and GENIUS projects

    International Nuclear Information System (INIS)

    Kihm, T.; Bobrakov, V.F.; Klapdor-Kleingrothaus, H.V.

    2003-01-01

    In this paper we present the first results of applying a digital processing technology in low-level gamma spectroscopy with HPGE detectors. An experimental gamma spectrometer using Flash ADC module is built and tested. The test system is now under development and shows major advantages over the traditional analog technologies. It will be installed for the GENIUS-TF and GENIUS projects in Gran-Sasso in early 2003

  16. Estudios por imágenes en reumatismo

    Directory of Open Access Journals (Sweden)

    Muñoz Ch. Sara, Dra.

    2012-07-01

    Los grandes avances tecnológicos de la última década han mejorado la calidad y cantidad de información que las distintas técnicas aportan, especialmente la RM; esto hace vislumbrar un cambio significativo en el diagnóstico por imágenes, ya que en el futuro no solo estará basado en los cambios morfológicos en órganos y tejidos; las imágenes obtenidas aportarán información bioquímica, molecular y fisiológica de los procesos patológicos facilitando su diagnóstico aun más precoz.

  17. Geschichtsbezogene und rechtspolitische Polonica im Bücherbestand Gottfried Lengnichs

    Directory of Open Access Journals (Sweden)

    Iwona Imańska

    2017-11-01

    Full Text Available Gottfried Lengnich, der Historiker und Syndikus der Stadt Danzig aus dem 18. Jahrhundert, hinterließ eine Büchersammlung mit über viertausend Büchern, die nach seinem Tode in zwei Auktionen im Juli und November 1774 versteigert werden sollten. Die Auktionskataloge befinden sich in der Staatsbibliothek zu Berlin – Stiftung Preußischer Kulturbesitz und sind auch online zugänglich. Wegen wissenschaftlicher Interessen Lengnichs befanden sich in seiner Bibliothek ca. 600 Polonica-Drucke, die meisten davon waren Abhandlungen im Themenfeld Geschichte, Recht und Politik. Die Analyse dieses Fragments des Bücherbestands Lengnichs bewies, dass der Syndikus eine perfekte Arbeitswerkstatt für sich schuf, indem er die Werke der meisten wichtigsten polnischen und fremden Autoren, die über die Geschichte und die Gesetzgebung Polens und Preußens schrieben, sammelte.

  18. Synthesis of Cyclic Py-Im Polyamide Libraries

    OpenAIRE

    Li, Benjamin C.; Montgomery, David C.; Puckett, James W.; Dervan, Peter B.

    2013-01-01

    Cyclic Py-Im polyamides containing two GABA turn units exhibit enhanced DNA binding affinity, but extensive studies of their biological properties have been hindered due to synthetic inaccessibility. A facile modular approach toward cyclic polyamides has been developed via microwave-assisted solid-phase synthesis of hairpin amino acid oligomer intermediates followed by macrocyclization. A focused library of cyclic polyamides 1–7 targeted to the androgen response element (ARE) and the estrogen...

  19. Agrupador de imágenes multimodal no supervisado

    OpenAIRE

    Pérez Hernando, Jesús

    2013-01-01

    Trabajo Fin de Máster donde se implementa un método multimodal para la clasificación de imágenes sin etiquetar y sin intervención humana. Treball Fi de Màster on s'implementa un mètode multimodal per a la classificació d'imatges sense etiquetar i sense intervenció humana. Master thesis for the Computer Science Engineering program.

  20. Topologieoptimierung im Creo-Umfeld mit ProTopCI

    OpenAIRE

    Simmler, Urs

    2016-01-01

    Wikipedia umschreibt die Topologieoptimierung als ein computerbasiertes Berechnungsverfahren, durch welches eine günstige Grundgestalt (Topologie) für Bauteile unter mechanischer Belastung ermittelt werden kann. Durch die Verwendung von 3D-Druck-Verfahren wird die Gestaltung der Komponenten revolutioniert, weil diese nicht mehr abhängig vom Fertigungsverfahren sind. Dabei werden auch optimale Gitterstrukturen innerhalb der Komponenten immer wichtiger. Diese neuen Herausforderungen können im C...

  1. Simulation von Heißrubbeln im Gesamtbremssystem

    OpenAIRE

    Könning, Maximilian

    2017-01-01

    Bremsenrubbeln ist eine fremderregte Schwingung des Bremssystems, die es in der Ent-wicklung zu vermeiden gilt. Eine Wirkungskette des Heißrubbelns wurde in einem Vorgängerprojekt erarbeitet und bildet die Grundlage für diese Arbeit. Die Entstehung des Heißrubbelns besteht aus verschiedenen Phasen und beginnt mit einer initialen Verwellung. Daraus resultieren im Bremssystem Bremsmomentschwankungen und die schwankende Reibleistung führt wiederum zu einem Wachstum der Bremsscheibenverformung. ...

  2. Frauen mit Eßstörungen im Ausdauersport

    OpenAIRE

    Bös, Annette

    2003-01-01

    Die vorliegende Arbeit untersucht das Phänomen Eßstörungen bei Ausdauersportlerinnen. Auf dem Hintergrund des identitätstheoretischen Ansatzes von Stahr et al. (1995) geht es um die Frage nach den Hauptverursachungsmomenten der Eßstörungen von sieben jungen Sportlerinnen. Im Rahmen einer qualitativen Sozialforschungsarbeit wurden sieben Athletinnen in einem problemzentrierten Interview zur Phase ihrer Eßstörungserkrankung befragt. Die Arbeit setzt sich zum Ziel, einen Beitrag zur systematisch...

  3. Aufgabenbezogene Differenzierung und Entwicklung des verbalen Selbstkonzepts im Anfangsunterricht

    OpenAIRE

    Lipowsky, Frank; Kastens, Claudia; Lotz, Miriam; Faust, Gabriele

    2011-01-01

    Die vorliegende Studie untersucht, wie sich aufgabenbezogene Differenzierung im Deutschunterricht auf die Entwicklung des verbalen Selbstkonzepts von Erst- und Zweitklässlern (Lesen und Schreiben) auswirkt. Die untersuchte Stichprobe setzt sich aus 735 Schülern des ersten Schuljahres zusammen, die 38 Klassen an staatlichen und privaten Grundschulen besuchen und die bis zum Ende des zweiten Schuljahres in ihrer Entwicklung untersucht wurden. Die Ergebnisse zeigen sowohl einen indirekten als au...

  4. Mediengestaltung im interkulturellen Vergleich. Eine Studie zu Mikroaspekten der Globalisierung

    OpenAIRE

    Vera-Stahl, Gilda

    2017-01-01

    Die vorliegende Arbeit befasst sich mit dem interkulturellen Vergleich von lokalen Werbespots aus Deutschland und Ecuador. Im Zentrum des Interesses steht die implizite Dimension der technisch gebundenen audiovisuellen Kommunikation, d.h. die Art und Weise, wie die Kommunikationsmedien – das Bild, die Sprache und die Musik – bei der Gestaltung der Spots verwendet werden. Ausgangspunkt der Untersuchung bildet der Ansatz von Nothnagel/Vera (2004, 2005), dass Habitusformen der Face-to-Face-...

  5. Collecting Virtual Reference Statistics with an IM Chat-Bot

    Directory of Open Access Journals (Sweden)

    Mason R.K. Hall

    2008-06-01

    Full Text Available A perennial problem in libraries is capturing accurate statistics. This article addresses this problem with the creative use of Web 2.0 tools: Meebo and AOL Instant Messenger. It describes the development and implementation of an instant messaging "stat-bot" that prompts staff to record virtual reference statistics via IM. Step-by-step guidelines and the perl script are provided.

  6. Business-Intelligence-Systeme im Spannungsfeld zwischen Usability und Sicherheit

    OpenAIRE

    Hinck, Thorsten

    2010-01-01

    Business-Intelligence-Systeme stehen im Spannungsfeld zwischen Usability und Sicherheit. Die Gefahren und Sicherheitsmaßnahmen für Informationssysteme werden ermittelt und ökonomisch in Bezug zur Gebrauchstauglichkeit gesetzt. Es entsteht ein Sicherheitsprofil für Business-Intelligence-Systeme. Business-Intelligence-Systems are in tension between Usability and IT-Security. Risks and safety measures of informationsystems are defined and set in (economic) regard to Usability. A security prof...

  7. QUARTERLY TECHNICAL REPORT FOR IN-MINE (IM) SYSTEM

    International Nuclear Information System (INIS)

    Zvi H. Meiksin

    2001-01-01

    A circuit that had been earlier lab-tested to eliminate multi-antenna interference in the In-mine (IM) system was fabricated, implemented and tested successfully in a system setting. An adaptive, tracking comb-filter for the through-the-earth (TTE) communications system was designed and implemented. This resulted in noticeable noise reduction. Studies for multi-channel transmission have begun

  8. ImSET: Impact of Sector Energy Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Roop, Joseph M.; Scott, Michael J.; Schultz, Robert W.

    2005-07-19

    This version of the Impact of Sector Energy Technologies (ImSET) model represents the ''next generation'' of the previously developed Visual Basic model (ImBUILD 2.0) that was developed in 2003 to estimate the macroeconomic impacts of energy-efficient technology in buildings. More specifically, a special-purpose version of the 1997 benchmark national Input-Output (I-O) model was designed specifically to estimate the national employment and income effects of the deployment of Office of Energy Efficiency and Renewable Energy (EERE) -developed energy-saving technologies. In comparison with the previous versions of the model, this version allows for more complete and automated analysis of the essential features of energy efficiency investments in buildings, industry, transportation, and the electric power sectors. This version also incorporates improvements in the treatment of operations and maintenance costs, and improves the treatment of financing of investment options. ImSET is also easier to use than extant macroeconomic simulation models and incorporates information developed by each of the EERE offices as part of the requirements of the Government Performance and Results Act.

  9. Zur mediopassiven 2. Und 3. Person dualis im indogermanischen

    Directory of Open Access Journals (Sweden)

    Bojan Čop

    1972-12-01

    Full Text Available Bekanntlich gibt es in einigen seltenen idg. Sprachen (im Arischen, Griechischen, Tocharischen auch Personal - suffixe für die 2. u n d 3. P. Du. des Mediopassivs. Von diesen sind die griechischen Ausgänge – 2. und 3. Du primär, 2. Du. sekundär, Du. sekundär sicher junge Neubildungen, s. z. B. Brugmann, Grdr.2 II 3 II, 657, § 602; Schwyzer, Gr. Gr. I 670, 672. Ein voll ausgebildetes System solcher Endungen besitzt das Arische; im Tocharischen kommt nur eine einzige Form mit solcher Endung vor, die die 2. P. Du. Med. lmperativi darstellt. Unter solchen Umständen scheint es schwierig, aus diesem Material wahrscheinliche Schlüsse für da_s Urindogermanische zu machen. Und doch ist gerade die tocharische Form, die uns eine ausserordentlich grosse Hilfe leistet, wenn man sie richtig zu beurteilen vermag. Die tocharische Endung, verbunden mit den arischen, wird unter Einschluss der allgemeinen Tendenzen und Regelungen im System der indogermanischen Personalsuffixe ohne Schwierigkeit die urindogermanische Urform erscheinen lassen.

  10. Report on converging insert moulding with µ-IM

    DEFF Research Database (Denmark)

    Islam, Aminul

    moulding with µ-IM  Task 5.2.1 and COTECH demonstrator: guide line for 5PRC production based on the concept of Task 5.2.1 Information and results provided by this deliverable will be directly used for one of the COTECH demonstrators production which will call for convergent insert moulding with µ......Task 5.2.1 deals with the technical feasibility of converging the state-of-the-art µ IM process with insert moulding to offer a wide range of multi-material µ components. The main objective of this deliverable is to summarize state-of-the-art information and to make the guideline needed...... for the convergence. In particular the following aspects are summed up in the deliverable:  Need for converging insert moulding with µ-IM  Objectives and expected outcome from task 5.2.1  State-of-the-art micro insert moulding and different scenario of micro insert moulding  Challenges ahead of converging insert...

  11. [Das Bild und die Wahrnehmung der Stadt und der städtischen Gesellschaft im Hanseraum im Mittelalter und in der frühen Neuzeit] / Juhan Kreem

    Index Scriptorium Estoniae

    Kreem, Juhan

    2009-01-01

    Arvustus: Das Bild und die Wahrnehmung der Stadt und der städtischen Gesellschaft im Hanseraum im Mittelalter und in der frühen Neuzeit. hrsg. v. Roman Czaja. Torun, 2004. Torunis 2002. aastal toimunud konverentsi materjalid. Projekti "Pilt ja linn" raames ilmunud publikatsioonide loendit saab näha aadressil http://www.historiaurbium.org/english/attivita_images_en.html.

  12. A study on nuclear heat load tolerable for NET/TF coils cooled by internal flow of helium II

    International Nuclear Information System (INIS)

    Hofmann, A.

    1988-02-01

    NbTi cables cooled by internal flow of superfluid helium are considered an option for the design of NET/TF coils with about 11 T peak fields. Starting from an available winding cross section of 0.61x0.61 m 2 for a 8 MA turns coil made of a 16 kA conductor it is shown that sufficient hydraulic cross section can be provided within such cables to remove the expected thermal load resulting from nuclear heating with exponential decay from inboard to outboard side of the winding. The concept is a pancake type coil with 1.8 K helium fed-in the high field region of each pancake. The temperature distribution within such coils is calculated, and the local safety margin is determined from temperature and field. The calculation takes account of nuclear and a.c. heating, and of thermal conductance between the individual layers and the coil casing. It is shown that operation with 1.8 K inlet and about 3 K outlet temperature is possible. The electrical insulation with about 0.5 mm thickness proves to provide sufficient thermal insulation. No additional thermal shield is required between the coil casing and the winding package. Two different types of conductors are being considered: a) POLO type cable with quadratic cross section and a central circular coolant duct, and b) an LCT type cable with two conductors wound in hand. Both concepts with about 500 m length of the cooland channels are shown to meet the requirements resulting from a peak nuclear heat load of 0.3 mW/cm 3 in the inboard turns. The hydraulic diameters are sufficient to operate each coils with self-sustained fountain effect pumps. Even appreciably higher heat loads with up to 3 mW/cm 3 of nuclear heating can be tolerated for the POLO type cable when the hydraulic diameter is enlarged to its maximum of 17 mm. (orig.) [de

  13. Medienpädagogische Aufgabenfelder hinsichtlich der Visualität im digitalen Zeitalter. Desiderate im Umgang mit visuellen Medienkulturen

    Directory of Open Access Journals (Sweden)

    Petra Missomelius

    2017-04-01

    Full Text Available Die bildungskulturell leitende Funktion des Buches diffundiert im digitalen Zeitalter mobiler und transversaler Systeme von Netzwerkmedien. Zudem sind soziokulturelle Lebenswelten wie Bildungsinstitutionen, Familie und Peers durch Heterogenität gekennzeichnet. Indem auch diese Teil des Geflechts medienkultureller Architekturen werden, geraten ehemals gültige Unterscheidungsparameter wie explizites und implizites, formelles und informelles Wissen ins Wanken. Grenzziehungen und konkurrierende Auffassungen gegenüber diesen, vormals als der Bildung entgegengesetzt wahrgenommenen, Bereichen erweisen sich nunmehr als problematisch. So spielt Visualität im Kontext multimodal zusammengesetzter Bildungsmaterialien eine zunehmende Rolle und wird als Möglichkeit des Umgangs mit Komplexität eingesetzt. Wenngleich somit die Zurückhaltung gegenüber (Bewegt-Bildmedien in der pädagogischen Praxis schwindet, so haben sich mit der Digitalisierung medienkulturell bedeutsame Felder eröffnet, welche erziehungswissenschaftlicher Beachtung bedürfen. Eine sich der Komplexität digitaler Medienkulturen stellende Medienpädagogik bringt mit sich, dass auch Funktion und Gebrauch visueller Medien im Kontext von Bildungsprozessen reflektiert stattfinden. Medienpädagogisch informiertes Agieren in visuellen Medienkulturen ist darüber hinaus heute gerade deshalb essentiell, da es sich bei digital generierter Visualität um eine neue Qualität im Unterschied zu traditionellen Bildmedien handelt, welche der Logik der Repräsentation entsprachen. Der Beitrag thematisiert Desiderate, die sich hinsichtlich des Visuellen datenbasierter Medien für die Medienpädagogik ergeben, und geht dabei auf kommunikative Bildlichkeit, auf paradigmatische mediale Formen und auf datengestützte Wissensgenerierung ein.

  14. Finanzmärkte – Unternehmungen – Informationen: Ergebnisse des Projektes im Wintersemester 2016/2017

    OpenAIRE

    Geyer, Helmut; Grau, Svenja; Giersch, Peter; Eckardt, Maximilian; Eder, Josephin; Catholy, Victoria; Pisak, Anastasia; Löser, Matthias; Jehring, Maximilian; Zhang, Haoyang; Grabengießer, Anja; Gruschwitz, Karoline; Heinrich, Katharina; Patzer, Vivien; Päsler, Florian

    2018-01-01

    Der vorliegende Beitrag der Wirtschaftswissenschaftlichen Schriften ist ein Sammelband, der die Beiträge der Studierenden des 2. Fachsemesters im Masterstudiengang General Management aus dem Wintersemester 2016/2017 umfasst. Die Einzelbeiträge wurden in einer zwei Monate dauernden Projektarbeit im Herbst 2016 erarbeitet und im Januar 2017 präsentiert. Der Themenschwerpunkt für dieses Jahr lag auf dem Bereich "Immobilien/Wohnungspolitik". Innerhalb dieser Vorgabe wurde ein breites Spektrum bea...

  15. [Photoionization ion mobility spectrometry (UV-IMS) for the isomeric volatile organic compounds].

    Science.gov (United States)

    Li, Hu; Niu, Wen-qi; Wang, Hong-mei; Huang, Chao-qun; Jiang, Hai-he; Chu, Yan-nan

    2012-01-01

    The construction and performance study is reported for a newly developed ultraviolet photoionization ion mobility spectrometry (UV-IMS). In the present paper, an UV-IMS technique was firstly developed to detect eleven isomeric volatile organic compounds including the differences in the structure of carbon chain, the style of function group and the position of function group. Their reduced mobility values were determined and increased in this order: linears alcohols homemade UV-IMS was around ppb-ppm.

  16. Demonstration of thin film pair distribution function analysis (tfPDF for the study of local structure in amorphous and crystalline thin films

    Directory of Open Access Journals (Sweden)

    Kirsten M. Ø. Jensen

    2015-09-01

    Full Text Available By means of normal-incidence, high-flux and high-energy X-rays, total scattering data for pair distribution function (PDF analysis have been obtained from thin films (tf, suitable for local structure analysis. By using amorphous substrates as support for the films, the standard Rapid Acquisition PDF setup can be applied and the scattering signal from the film can be isolated from the total scattering data through subtraction of an independently measured background signal. No angular corrections to the data are needed, as would be the case for grazing incidence measurements. The `tfPDF' method is illustrated through studies of as-deposited (i.e. amorphous and crystalline FeSb3 films, where the local structure analysis gives insight into the stabilization of the metastable skutterudite FeSb3 phase. The films were prepared by depositing ultra-thin alternating layers of Fe and Sb, which interdiffuse and after annealing crystallize to form the FeSb3 structure. The tfPDF data show that the amorphous precursor phase consists of corner-sharing FeSb6 octahedra with motifs highly resembling the local structure in crystalline FeSb3. Analysis of the amorphous structure allows the prediction of whether the final crystalline product will form the FeSb3 phase with or without excess Sb present. The study thus illustrates how analysis of the local structure in amorphous precursor films can help to understand crystallization processes of metastable phases and opens for a range of new local structure studies of thin films.

  17. Incidental findings in chest X-rays; Zufallsbefunde im Roentgenthorax

    Energy Technology Data Exchange (ETDEWEB)

    Wielpuetz, M.O.; Kauczor, H.U. [Universitaetsklinikum Heidelberg, Klinik fuer Diagnostische und Interventionelle Radiologie, Heidelberg (Germany); Universitaet Heidelberg, Translational Lung Research Center (TLRC), Deutsches Zentrum fuer Lungenforschung (DZL), Heidelberg (Germany); Universitaetsklinikum Heidelberg, Klinik fuer Diagnostische und Interventionelle Radiologie mit Nuklearmedizin, Thoraxklinik, Heidelberg (Germany); Weckbach, S. [Universitaetsklinikum Heidelberg, Klinik fuer Diagnostische und Interventionelle Radiologie, Heidelberg (Germany); Universitaet Heidelberg, Translational Lung Research Center (TLRC), Deutsches Zentrum fuer Lungenforschung (DZL), Heidelberg (Germany)

    2017-04-15

    Conventional projection radiography (chest x-ray) is one of the most frequently requested procedures in radiology. Even though chest x-ray imaging is frequently performed in asymptomatic patients for preoperative assessment, clinically relevant incidental findings are relatively scarce. This is due to the relatively low sensitivity of chest x-rays where few clinically relevant incidental findings are to be expected, as any detectable pathologies will as a rule already be clinically symptomatic. Recommendations from relevant societies for the management of incidental findings, apart from the clarification of incidental nodules, do not exist. This review article therefore describes the most frequent and typical incidental findings of lung parenchyma (apart from pulmonary nodules), mediastinal structures including the hilum of the lungs, pleura, chest wall and major vessels. Also described are those findings which can be diagnosed with sufficient certainty from chest x-rays so that further clarification is not necessary and those which must be further clarified by multislice imaging procedures or other techniques. (orig.) [German] Eine der haeufigsten Untersuchungen in der Radiologie ist die konventionelle Projektionsradiographie des Thorax (Roentgenthorax). Auch wenn projektionsradiographische Aufnahmen im Rahmen einer praeoperativen Abklaerung haeufig als orientierende Untersuchung angefertigt werden, sind - bedingt durch die relativ geringe Sensitivitaet des Roentgenthorax - wenig klinisch relevante Zufallsbefunde zu erwarten, da nachweisbare Pathologien in der Regel bereits auch klinisch apparent sind. Empfehlungen entsprechender Fachgesellschaften zu Zufallsbefunden im Roentgenthorax jenseits der Abklaerung von Rundherden liegen nicht vor. Die vorliegende Arbeit beleuchtet daher haeufige und typische Zufallsbefunde des Lungenparenchyms (ausser den Lungenrundherden), der mediastinalen Strukturen einschliesslich der Hili, der Pleura, der Thoraxwand sowie der

  18. Die Freunde im und die Freude am Fernsehen

    Directory of Open Access Journals (Sweden)

    Amina Ovcina Cajacob

    2012-09-01

    Full Text Available Das Ziel der vorliegenden Arbeit besteht darin, die Wirkungen von Popstars und Popbands auf Jugendliche (13- bis 17-Jährige zu erforschen. Im Mittelpunkt der Interessen steht die Frage, welche Wirkungen aus der Rezeption von Musiksendungen (bzw. Videoclips von Musiksendern entstehen und welche Charakteristika innerhalb der aufgebauten Beziehungen zu den Stars bemerkbar sind. Andererseits wurden die Unterschiede und Parallelen zwischen parasozialen Beziehungen zu den Stars und orthosozialen Beziehungen aufgezeigt. Im Zusammenhang mit der empirischen Untersuchung bezieht sich die Autorin auf den Uses-and-Gratifications-Approach, wobei die bedürfnissbefriedigenden Wirkungen von Musikkanälen und den dazu gehörigen Popstars im Mittelpunkt stehen. Mit Hilfe des Uses-and-Gratifications-Approach wird angenommen, dass das Konsumieren der Musiksendungen und der Musikstars von den Jugendlichen gezielt zur Befriedigung bestimmter Bedürfnisse eingesetzt wird.The objective of this study is to explore the effects of pop stars on adolescents (aged between 13 and 17. The focus of interest is the question what effect music channels (i.e. video clips from music channels produce and what characteristics are noticeable from the formed relationship between adolescents and pop stars. On the other side, parallels and differences have been drawn between the para-social relationships to pop stars and ortho-social relationships. In connection with empirical study, the author also refers to Uses-and Gratification-Approach where the need satisfying effects of music channels and pop stars are in focus. With the help of Uses-and Gratification-Approach it will be assumed, that aim of watching music channels and therefore pop stars will be pointed toward the gratification of specific needs.

  19. ImBuild: Impact of building energy efficiency programs

    Energy Technology Data Exchange (ETDEWEB)

    Scott, M.J.; Hostick, D.J.; Belzer, D.B.

    1998-04-01

    As part of measuring the impact of government programs on improving the energy efficiency of the Nation`s building stock, the Department of Energy Office of Building Technology, State and Community Programs (BTS) is interested in assessing the economic impacts of its portfolio of programs, specifically the potential impact on national employment and income. The special-purpose version of the IMPLAN model used in this study is called ImBuild. In comparison with simple economic multiplier approaches, such as Department of Commerce RIMS 2 system, ImBuild allows for more complete and automated analysis of the economic impacts of energy efficiency investments in buildings. ImBuild is also easier to use than existing macroeconomic simulation models. The authors conducted an analysis of three sample BTS energy programs: the residential generator-absorber heat exchange gas heat pump (GAX heat pump), the low power sulfur lamp (LPSL) in residential and commercial applications, and the Building America program. The GAX heat pump would address the market for the high-efficiency residential combined heating and cooling systems. The LPSL would replace some highly efficient fluorescent commercial lighting. Building America seeks to improve the energy efficiency of new factory-built, modular, manufactured, and small-volume, site-built homes through use of systems engineering concepts and early incorporation of new products and processes, and by increasing the demand for more energy-efficient homes. The authors analyze a scenario for market penetration of each of these technologies devised for BTS programs reported in the BTS GPRA Metrics Estimates, FY99 Budget Request, December 19, 1997. 46 figs., 4 tabs.

  20. Thermische Verletzungen im Kindesalter: Eine retrospektive Kohortenstudie von 212 Fällen

    OpenAIRE

    Sperling, Patrik Leonhart

    2012-01-01

    Anhand einer retrospektiven Datenanalyse sollen Verteilungsmuster von Verbrennungen und Verbrühungen bezogen auf Alter und Geschlecht untersucht werden. Erfasst wurden 212 Patienten im Alter von 0 bis 16 Jahren betrachtet, die im Zeitraum vom 01.01.2004 bis zum 31.12.2009 auf Grund einer thermischen Verletzung stationär im Universitätsklinikum Würzburg der Julius-Maximilians-Universität Würzburg behandelt wurden. Den größten Anteil thermischer Verletzungen im Kindesalter stellen Verbrühungen ...

  1. A two-stage extraction procedure for insensitive munition (IM) explosive compounds in soils.

    Science.gov (United States)

    Felt, Deborah; Gurtowski, Luke; Nestler, Catherine C; Johnson, Jared; Larson, Steven

    2016-12-01

    The Department of Defense (DoD) is developing a new category of insensitive munitions (IMs) that are more resistant to detonation or promulgation from external stimuli than traditional munition formulations. The new explosive constituent compounds are 2,4-dinitroanisole (DNAN), nitroguanidine (NQ), and nitrotriazolone (NTO). The production and use of IM formulations may result in interaction of IM component compounds with soil. The chemical properties of these IM compounds present unique challenges for extraction from environmental matrices such as soil. A two-stage extraction procedure was developed and tested using several soil types amended with known concentrations of IM compounds. This procedure incorporates both an acidified phase and an organic phase to account for the chemical properties of the IM compounds. The method detection limits (MDLs) for all IM compounds in all soil types were regulatory risk-based Regional Screening Level (RSL) criteria for soil proposed by the U.S. Army Public Health Center. At defined environmentally relevant concentrations, the average recovery of each IM compound in each soil type was consistent and greater than 85%. The two-stage extraction method decreased the influence of soil composition on IM compound recovery. UV analysis of NTO established an isosbestic point based on varied pH at a detection wavelength of 341 nm. The two-stage soil extraction method is equally effective for traditional munition compounds, a potentially important point when examining soils exposed to both traditional and insensitive munitions. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Einsatz von Skype im Unternehmen: Chancen und Risiken

    OpenAIRE

    Messerer, Thomas

    2016-01-01

    Gegenstand dieser Studie ist der Internet-Telefoniedienst Skype, der sich grundsätzlich an Endanwender richtet. Im Mittelpunkt steht dabei die Frage, ob und unter welchen Umständen sich dieses Skype-Angebot auch für den Einsatz in Unternehmen eignet. Microsoft bietet darüber hinaus eine Skype-Lösung (ehemals Lync) an, die sich ausdrücklich an Unternehmen wendet. Deren Markenname ist „Skype for Business“. Dieser Dienst wird in der vorliegenden Studie nicht untersucht; dazu hat das Autorenteam ...

  3. ODE/IM correspondence and modified affine Toda field equations

    Energy Technology Data Exchange (ETDEWEB)

    Ito, Katsushi; Locke, Christopher

    2014-08-15

    We study the two-dimensional affine Toda field equations for affine Lie algebra g{sup ^} modified by a conformal transformation and the associated linear equations. In the conformal limit, the associated linear problem reduces to a (pseudo-)differential equation. For classical affine Lie algebra g{sup ^}, we obtain a (pseudo-)differential equation corresponding to the Bethe equations for the Langlands dual of the Lie algebra g, which were found by Dorey et al. in study of the ODE/IM correspondence.

  4. Using scenarios for dissemination - Experiences from the IMS GLOBEMEN project

    DEFF Research Database (Denmark)

    Ollus, Martin; Hartel, Ingo; Tølle, Martin

    2002-01-01

    due to the complexities of the interdisciplinary field addressed. As an instrument for communication to the non-specialist public the IMS GLOBEMEN project produces a web-based scenario as part of its dissemination activities. It is aimed at giving a practical overview of specific challenges...... in the field and contributions from the project. Based upon a generic Virtual Enterprise Reference Architecture (called VERA) the partners in the project have developed a set of protypes to be implemeted in their own business processes. The results will be illutrated in one integrated scenario....

  5. Morphological and physiological investigations on mutants of Fusarium monoliforme IM

    International Nuclear Information System (INIS)

    Gancheva, V.

    1996-01-01

    High-producing mutants of Fusarium moniliforme IM are obtained as a result of gamma irradiation. The cultural characteristics of mutant strains 3284, 3211 and 76 following incubation of the producers for 14 days on potato-glucose agar are described. The colour of the aerial and substrate mycelium and the ability of the mutant strains to form conidiae and pigments are discussed in detail. The differences in the ability of mutants to assimilate different carbon and nitrogen sources are of specific importance for modelling nutrient media for submerged cultivation of F. moniliforme. 2 tabs., 2 figs. 7 refs

  6. [Leben im Eismeer - Tauchuntersuchungen zur Biologie arktischer Meerespflanzen und Meerestiere

    Science.gov (United States)

    Lippert; Karsten; Wiencke

    2000-01-01

    Die Maske wird nochmals auf Dichtigkeit überprüft, der Knoten der Sicherungsleine mit zwei halben Schlägen fixiert, dann rutscht die Taucherin von der Eiskante in das kalte Wasser. Eine halbe Stunde vergeht, bevor ihr Kopf wieder aus dem Eisloch auftaucht und sie ein großes Sammelnetz nach oben reicht, gefüllt mit verschiedenen Arten von Makroalgen. Obwohl noch große Flächen des Kongsfjordes im arktischen Spitzbergen zugefroren sind und das Festland von einer dicken Schneedecke bedeckt ist, hat unter Wasser in den Algenwäldern bereits der Sommer und damit die Saison der Meeresbiologen begonnen.

  7. Die filmstilistische Darstellung von Klaras Gehbehinderung im Kinderfilm "Heidi"

    Directory of Open Access Journals (Sweden)

    Maria Ohrfandl

    2016-09-01

    Full Text Available Dieser Beitrag soll die Forschungslücke zur Darstellung von Behinderungen speziell im Kinderfilm im deutschsprachigen Raum füllen. Auf Basis einer neoformalistisch orientierten Filmanalyse nach Bordwell und Thompson (2008, wird anhand von drei Filmsequenzen eine mögliche Lesart des Kinderfilms "Heidi" (Marcus 2005 entwickelt, um die filmstilistische Darstellung der Gehbehinderung des Mädchens Klara zu untersuchen. Die Ergebnisse werden mit theoretischen Überlegungen zur Problematik der Begriffsbestimmung von Körperbehinderung sowie zur Mobilität und Selbstbestimmung von Menschen mit Körperbehinderungen in Bezug gesetzt. Dabei zeigt sich im Wesentlichen, dass im Kinderfilm "Heidi" (Marcus 2005 Klaras Gehbehinderung als 'heilbare Krankheit' und der Rollstuhl als Einschränkung von Mobilität begriffen wird. Außerdem unterliegt Klara aufgrund ihrer Körperbehinderung überwiegend der Fremdbestimmung von Erwachsenen. Zur Klärung wahrscheinlicher filmischer Bildungspotenziale werden die Ergebnisse schließlich anhand der von Jörissen und Marotzki (2009 entwickelten Orientierungsdimensionen "Wissens-, Handlungs-, Grenz- und Biographiebezug" diskutiert. This article aims to bridge a knowledge gap by showing ways of representing disabilities in the German children film genre. Using Bordwell and Thomson's (2008 neoformalistically orientated film analysis approach, the movie "Heidi" (Marcus 2005 is analysed. Bordwell and Thompson's (2008 method is applied to three sequences of "Heidi" in order to present an interpretation and to discuss the representation of Clara's walking impediment. The results are then associated with theoretical considerations regarding the mobility and self-determination of people with disabilities and problematic definitions of the term 'physical disability'. It is shown that characters in the children's film "Heidi" (Marcus 2005 regard Clara's walking impediment as a 'curable disease' and the wheelchair as a limitation

  8. Multimediale Kommunikationsarchitekturen: Herausforderungen und Weiterentwicklungen der Forschungen im Kulturraum Internet

    Directory of Open Access Journals (Sweden)

    Winfried Marotzki

    2008-04-01

    Full Text Available Im Folgenden setze ich mich mit der Frage auseinander, wie der sich rasch verändernde kulturelle Raum Internet forschungsmässig zu erschliessen ist. Dabei möchte ich weniger den aktuellen Stand der Internet Forschung bilanzieren, das ist durch verschiedene einschlägige Publikationen bereits geschehen. Vielmehr werde ich mich darauf konzentrieren, die Hauptveränderungen des Internet in den letzten Jahren zu skizzieren, um daran anknüpfend einige ausgewählte methodische Probleme, die damit verbunden sind, zu bearbeiten.

  9. "ARZT IM GANZEN SPEKTRUM" ["PHYSICIAN IN THE FULL SPEKTRUM"

    Directory of Open Access Journals (Sweden)

    Mitzkat, Anika

    2006-11-01

    Full Text Available [english] For more than 20 years teaching in the medical program at Witten/Herdecke Private University has followed the goal of introducing students to the reality of patient care by a practical approach. The “adaptive physician personality” describes the educational objective of a physician who is able to orient towards “the full spectrum” of his professional core competencies. In regard to the “adaptive physician personality” four Integrated Curricula (Communication, Science, Ethics, and Health Economy had been developed along with the introduction of a model medical program in 2000. Witten/Herdecke University thereby today addresses the requirements defined by the New Medical Licensure Act of 27.06.2002 and brings forward at the same time a program which prepares the medical student for the multi-dimensional responsibilities in the reality of modern health care. This article describes the Integrated Curricula exemplified by the Communication curriculum. This relatively young area of medical teaching in Germany is still extensively unexplored concerning evidence-based research about its effectiveness and efficiency of teaching. [german] Die Lehre im Studiengang Humanmedizin an der Privaten Universität Witten/Herdecke (UWH verfolgt seit mehr als 20 Jahren das Ziel, Studierende praxisnah an die Realität der Patientenversorgung heranzuführen. Das Ausbildungsziel des Medizinstudiums ist dabei die ”lernfähige Arztpersönlichkeit”, die sich möglichst „im ganzen Spektrum” ärztlicher Kernkompetenzen zu orientieren vermag. Im Hinblick auf das Ziel der „lernfähigen Arztpersönlichkeit“ wurden mit der Einführung des Modellstudiengangs Medizin im Jahr 2000 vier Integrierte Curricula (Kommunikation, Wissenschaft, Ethik und Gesundheitsökonomie aufgebaut. Die Lehre an der Universität Witten/Herdecke geht damit einerseits auf die Anforderungen, die mit Einführung der neuen Approbationsordnung für Ärzte vom 27.06.2002 an

  10. Primary fibrosarcoma im small intestine of dog - Case report

    OpenAIRE

    Geórgia Modé Magalhães; Juliana Santilli; Sabryna Gouveia Calazans; Lilian Toshiko Nishimura; Sofia de Amorim Cerejo; Fernanda Gosuen Gonçalves Dias

    2015-01-01

    ABSTRACT. Magalhães G.M., Santilli J., Calazans S.G., Nishimura L.T., Cerejo S.A. & Dias F.G.G. [Primary fibrosarcoma im small intestine of dog - Case report.] Fibrossarcoma primário em intestino delgado de cão - Relato de caso. Revista Brasileira de Medicina Veterinária, 37(2):145-148, 2015. Programa de Pós-Graduação em Medicina Veterinária de Pequenos Animais, Universidade de Franca, Av. Dr. Armando Salles Oliveira, 201, Cx postal 82, Parque Universitá- rio, Franca, SP 14404-600, Brasil. E-...

  11. Sexualität im Werk Arno Schmidts

    OpenAIRE

    Reischert, Jessica

    2006-01-01

    Die Sexualität im Frühwerk Arno Schmidts stellt ein umfangreiches und komplexes Thema dar, das dennoch auf gewisse Grundmuster und –vorgänge reduziert werden kann. So haben sich bei der Begegnung von Menschen untereinander klare Linien ergeben, anhand derer viele Gespräche eingeordnet und analysiert werden können. Unterschieden werden können mehrere Gesprächstypen, in denen sich bestimmte Verhaltensweisen der Schmidtschen Protagonisten zeigen: In den geschlechtlich gemischten Gesprächsrunden ...

  12. Economic management system at the im. Abakumova mine

    Energy Technology Data Exchange (ETDEWEB)

    Martynenko, V.F. (Shakhta im. Abakumova (Ukraine))

    1992-08-01

    Decribes new methods of settling accounts between mine departments, and methods of paying wages introduced in the im. Abakumova mine. Internal banknotes were introduced in 1991. Ways of clearing the cost of materials, depreciation and repair work are explained. Claims of mine departments are settled by arbitration committees. It was found that the new system of financial self-dependence of mine departments prevented downtime from occurring. Losses of coal reserves were reduced in 1991 by 28% compared to 1990. In the first quarter of 1992, labor efficiency increased by 6% compared to the first quarter in 1991.

  13. Psychiatrie im Nationalsozialismus. Zwangssterilisation und Euthanasie am Beispiel des Saarlandes

    Directory of Open Access Journals (Sweden)

    Torsten Mergen

    2006-03-01

    Full Text Available In seiner ausführlichen und anhand zahlreicher Patientenakten erarbeiteten Dissertationsschrift untersucht Christoph Braß die Folgen des rassenhygienischen Denkens am Beispiel des Saarlandes von 1935 bis 1945. Dabei analysiert er einerseits systematisch die Vorgänge im Rahmen der Zwangssterilisation von psychisch Kranken und Behinderten, andererseits zeigt er exemplarisch Vorgeschichte, Verlauf und Ergebnisse der Euthanasie an saarländischen Patienten. Es entsteht eine eindrucksvolle und durch die dichte Darstellung Betroffenheit auslösende Studie, die eine wichtige Lücke der NS-Forschung schließt.

  14. Der antiskeptische Boden unter dem Gehirn im Tank

    OpenAIRE

    Müller, Olaf L.

    2001-01-01

    Crispin Wright hat die bislang beste Rekonstruktion von Putnams Beweis gegen die skeptische Hypothese vom Gehirn im Tank vorgelegt. Aber selbst in Wrights Fassung hat der Beweis einen Mangel: Er wird mithilfe eines Prädikates wie z.B. "Tiger" geführt und funktioniert nur, wenn man sich darauf verlassen kann, dass es Tiger wirklich gibt. Aber die Skeptikerin bestreitet, über die Existenz von Tigern bescheid zu wissen. Das Problem lässt sich dadurch beheben, dass man den Beweis – statt mit dem ...

  15. Attempt to promote hospital management by IM Public Platform

    Directory of Open Access Journals (Sweden)

    Hui CHEN

    2014-06-01

    Full Text Available Thisarticle has analyzed the contribution of modern IT to hospital management: using public platform of IM (instant message/communication will make it more convenient and efficient to conduct communication with (prior to the treatment, conduct treatment, and provide post-treatment service for patients and their family; withthe set-up of a smooth and efficient information channel set up, the relationship between patients and doctors will be greatly improved ,thus reputation and credibility of the hospital and its doctors will be promoted; when the public has better received the hospital and its doctors, social harmony will be achieved. 

  16. Verminderung der Prüfungsangst durch Modellernen im Klassenzimmer

    OpenAIRE

    Ellgring, Johann Heinrich; Elbing, Eberhard

    2010-01-01

    Die Wirksamkeit des Modellernens im Klassenzimmer zur Veränderung der Prüfungsangst wurde bei 152 Knaben und 164 Mädchen der Klassen 5-8 einer Hauptschule untersucht. Den Schülern wurden die Angst-Skalen (TASe und GASC) von Sarason vorgelegt. Anhand der Fragebogenergebnisse wurden die Kinder den Kategorien "hochängstlich" (HA), "mittelängstlich" (MA) und "niedrigängstlich" (NA) zugeordnet. Für 3,5 Monate wurden die folgenden Paarbildungen (Banknachbarn) beibehalten: HA neben HA, MA und NA, NA...

  17. Der Wortschatz als "Wahrheitsvermittler" im außenpolitischen Pressekommentar

    Directory of Open Access Journals (Sweden)

    Vida Jesenšek

    1998-12-01

    Full Text Available Bekannterweise weist die ausgewählte journalistische Textsorte eine spezifische textuelle Struktur auf; ihre inhaltliche (evaluative und intentionale Komponente sind zunächst in Kürze zu erläutern. Es zeigt sich, daß die Bewertung als obligatorisches Element eines Kommentartextes textstrukturell und stilistisch-pragmatisch bedingt ist und daß sie im Prinzip mittels Lexik realisiert wird. Das Funktionieren der Lexik als Bewertungsträger wird anschließend aufgrund einer exemplarischen Fallanalyse dargestellt, wobei hauptsächlich Zusammenhänge zwischen textstrukturellen Besonderheiten der Kommentartexte und stilistisch-pragmatischen Eigenschaften der Lexik interessieren.

  18. Entwicklung der Reglementierung von 10 MEM-Berufen im Kontext von Bildungsreformen und dem Wandel in der Arbeitswelt: Eine Kurzstudie im Auftrag von LIBS: Eine Kurzstudie im Auftrag von LIBS Industrielle Berufslehren Schweiz, Baden

    OpenAIRE

    Egg, Maria Esther; Renold, Ursula

    2015-01-01

    Im Auftrag der LIBS Industrielle Berufslehren Schweiz, hat die KOF die Entwicklung von 10 MEM1-Berufsbildern seit dem ersten Berufsbildungsgesetz dargestellt und diese eingebettet in eine kurze Zusammenfassung der wichtigsten Etappenschritte des Schweizer Berufsbildungssystems.

  19. Synthesis and DNA binding properties of 1-(3-aminopropyl)-imidazole-containing triamide f-Im*PyIm: a novel diamino polyamide designed to target 5'-ACGCGT-3'.

    Science.gov (United States)

    Satam, Vijay; Babu, Balaji; Porte, Alexander; Savagian, Mia; Lee, Megan; Smeltzer, Thomas; Liu, Yang; Ramos, Joseph; Wilson, W David; Lin, Shicai; Kiakos, Kostantinos; Hartley, John A; Lee, Moses

    2012-09-15

    A novel diamino/dicationic polyamide f-Im(*)PyIm (5) that contains an orthogonally positioned aminopropyl chain on an imidazole (Im(*)) moiety was designed to target 5'-ACGCGT-3'. The DNA binding properties of the diamino polyamide 5, determined by CD, ΔT(M), DNase I footprinting, SPR, and ITC studies, were compared with those of its monoamino/monocationic counterpart f-ImPyIm (1) and its diamino/dicationic isomer f-ImPy(*)Im (2), which has the aminopropyl group attached to the central pyrrole unit (Py(*)). The results gave evidence for the minor groove binding and selectivity of polyamide 5 for the cognate sequence 5'-ACGCGT-3', and with strong affinity (K(eq)=2.3×10(7) M(-1)). However, the binding affinities varied according to the order: f-ImPy(*)Im (2)>f-ImPyIm (1)≥f-Im(*)PyIm (5) confirming that the second amino group can improve affinity, but its position within the polyamide can affect affinity. Copyright © 2012 Elsevier Ltd. All rights reserved.

  20. Aktuelle Tendenzen im computerunterstützten (Fach- Fremdsprachenunterricht

    Directory of Open Access Journals (Sweden)

    Pawel Szerszeń

    2015-03-01

    Full Text Available Die heutigen Entwicklungen im Bereich der Kommunikations-und Informationstechnologien tragen u.a. dazu bei,dass wir immer wieder mit neuen E-Learning-Angeboten im (Fach-Fremdsprachenunterricht konfrontiert werden. Diese Tatsa-che stellt u.a. die FremdsprachendidaktikerInnen vor neue Herausforderungen, für die eine kritische Reflexion über die didakti-sche Effizienz von E-Learning-Produkten Vorrang hat. Für eine solche didaktische Reflexion muss jedoch zunächst geklärt wer-den, welche Haupttypen von E-Learning-Produkten bestehen. Das Hauptziel des vorliegenden Beitrags ist somit der Versuch, diezurzeit bestehenden Haupttypen zu erfassen, zu kategorisieren sowie mit einigen Beispielen zu veranschaulichen wie auch aufinteressante Features ausgewählter Lernplattformen/Lernprogramme und auf einige neue E-Learning-Tendenzen hinzuweisen.Dieser Überblick stellt eine nötige und geeignete Grundlage für eine zukünftig mögliche Effizienzreflexion und-diskussion vordem Hintergrund möglicher Produktvergleiche dar

  1. Medienkompetenz multiplizieren? Entwicklung eines Multiplikator/-innenkonzepts im Lehramtsstudium

    Directory of Open Access Journals (Sweden)

    Antje Müller

    2017-02-01

    Full Text Available Zur Förderung von Medienkompetenz und medienpädagogischer Kompetenz in der universitären Lehramtsausbildung wurde an der Justus-Liebig-Universität Gießen ein Lehrprojekt initiiert, das an der aktuellen technologischen Ausstattung von deutschen Schulen ansetzt. Als Zugang wurde die Technologie der interaktiven Whitebords gewählt, um gegenwärtige Entwicklungen der Digitalisierung von Unterrichtsräumen zu thematisieren und dabei ausgewählte Aspekte von Medienkompetenz zu fördern. In dem Projekt haben verschiedene Einrichtungen der Universität und der Lehrerbildung kooperiert, um eine Multiplikator/-innenschulung für Studierende zu erarbeiten und zu etablieren. Es wurde eine 28-stündige Qualifizierungsreihe entwickelt, die sich aus modularisierten Workshops zur medientechnischen und -didaktischen Auseinandersetzung mit interaktiven Whiteboards, Elementen der Tutor/-innenausbildung sowie der Erarbeitung eines eigenen Unterrichtsentwurfes zusammensetzt. In dem Artikel werden die entwickelten Module vorgestellt und bewertet, inwieweit sie den von Herzig, Aßmann und Klar (2014 formulierten Zielvorstellungen zur Medienkompetenzförderung für das Lehramtsstudium entsprechen. Im Abgleich mit diesen Zielvorstellungen werden Entwicklungspotentiale des Konzepts identifiziert. Darüber hinaus fliessen Ergebnisse der praktischen Durchführung in Optimierungsvorschläge zur Steigerung der Nachhaltigkeit und Qualität der didaktischen Kompetenzen zum Einsatz von interaktiven Whiteboards in der Lehramtsausbildung – und darüber vermittelt im Schulunterricht – ein.

  2. Integrated municipal wind power concepts; Windenergienutzung im staedtischen Verbund

    Energy Technology Data Exchange (ETDEWEB)

    Kolbert, D.; Richert, F. [Ventis Energietechnik GmbH, Braunschweig (Germany)

    1998-06-01

    The role of wind power in the industrial sector currently depends very much on its technical and economic integrability in existing conventional supply structures. The most important questions in this context relate to capacity effects, adapted operating methods of conventional power suppliers, and, most important of all, operational energy production costs. In some regions alternative energy supply concepts are not yet or not sufficiently available. However, these will nevertheless offer ways of installing energy systems with a large renewable segment. The chances of bringing such projects to fruition depend for one thing on the climate, which may either stimulate or deter from development work on renewables (wind power, solar energy), and for another, often in apparent opposition to the former, on the oftentimes poorly developed infrastructure and economic strength of the region in question. [Deutsch] Die Bedeutung der Windenergienutzung im industrialisierten Bereich ist derzeit verknuepft mit deren technischen und oekonomischen Integrationsfaehigkeit in bestehende, konventionelle Versorgungsstrukturen. Im Vordergrund steht hierbei die Klaerung der Fragestellungen nach Kapazitaetseffekten, angepassten Betriebsweisen konventioneller Stromerzeuger und, in erster Linie, betriebswirtschaftlichen Energieerzeugungskosten. Derzeit bieten die Regionen, in denen eine anderweitige Versorgung noch nicht oder in nicht ausreichendem Masse existieren Moeglichkeiten zur Installation von Energiesystemen mit hoher regenerativer Durchdringung. Fuer die Realisation solcher Projekte stehen sich haeufig die klimatischen Bedingungen, die einerseits z.T. die Ursache fuer den geringen Entwicklungsstand sind, andererseits aber auch guenstige Voraussetzungen fuer die Nutzung regenerativer Energien (Wind, Sonne) bieten, der meist schlechten Infrastruktur und der geringen Wirtschaftskraft gegenueber. (orig./MSK)

  3. Anmerkungen zur Aufrichtigkeit im russischen Autorenkino der 2010er

    Directory of Open Access Journals (Sweden)

    Irina Souch

    2017-06-01

    Full Text Available Obwohl der Begriff der Aufrichtigkeit seit längerer Zeit in der westlichen Filmtheorie mit Bezug auf einen bestimmten Regiestil verwendet worden ist, manifestiert sich dieser Trend in Russland erst seit Kurzem. Der Essay beginnt mit einer Betrachtung der diskursiven Anwendungen des Konzepts von Aufrichtigkeit zu, um sich anschließend den Filmen dreier junger russischer Regisseurinnen anzunähern: Oksana Byčkovas Eshche odin god / Another Year (2014, Nigina Sajfullaevas Kak menja zovut/ Sag mir, wer ich bin (2014, sowie Natalija Meščaninovas Kombinat „Nadežda“ / Fabrik der Hoffnung (2014. Obwohl sie der sogenannten neuen Welle des Autorenkinos („novaja režisserskaja volna“ zugeordnet werden, fechten die Positionen, die diese Regisseurinnen gegenüber ihren Vorgängern, aber auch ihren Zeitgenossen einnehmen, sowohl in Russland als auch dem Westen eine einfache Zuordnung an. Die Filme bieten einen Einblick in das Anliegen der Regisseurinnen, die gesellschaftlichen und emotionalen Sorgen ihrer Generation auf eine ehrliche und realistische Art und Weise auszudrücken. Eine sorgfältige Untersuchung unterstreicht die unterschiedlich verwendeten, aber dennoch gemeinsamen stilistischen, narrativen und thematischen Elemente, die sie im Film einsetzen. Im Laufe der Untersuchungen begegnet die Aufrichtigkeit nicht nur als diskursives Phänomen, sondern auch als eine vielseitige kulturelle Praxis. Die Mittel, mit denen die einzelnen Filme versuchen bei den Zuschauern eine emotionale Reaktion hervorzurufen, berechtigen die Einordnung einer solchen ästhetischen Taktik als aufrichtig und ehrlich.

  4. Utility of the ImPACT test with deaf adolescents.

    Science.gov (United States)

    Reesman, Jennifer; Pineda, Jill; Carver, Jenny; Brice, Patrick J; Zabel, T Andrew; Schatz, Philip

    2016-02-01

    The goals of the study included empirical examination of the utility of the Immediate and Post-Concussion Assessment and Cognitive Testing (ImPACT) test with adolescents who are deaf or hard-of-hearing and to investigate patterns of performance at baseline that may arise in the assessment of this population. Baseline assessment of student-athletes has been conducted on a widespread scale with focus on performance of typically developing student-athletes and some clinical groups, though to date no studies have examined adolescents who are deaf or hard-of-hearing. Retrospective and de-identified ImPACT baseline test used with deaf and hard-of-hearing high-school student-athletes (N = 143; 66% male, mean age = 16.11) was examined. Review indicated significant differences in some composite scores between the deaf and hard-of-hearing group and hearing normative comparisons. A possible marker of task misunderstanding was identified to occur more frequently within the deaf and hard-of-hearing sample (13% in deaf sample vs. .31% in hearing sample). Results may provide support for the consideration and use of additional measures to ensure comprehension of task demands when considering this tool for use with deaf and hard-of-hearing adolescents.

  5. International Conference on Informatics and Management Science (IMS)

    CERN Document Server

    Informatics and Management Science III

    2013-01-01

    The International Conference on Informatics and Management Science (IMS) 2012 will be held on November 16-19, 2012, in Chongqing, China, which is organized by Chongqing Normal University, Chongqing University, Shanghai Jiao Tong University, Nanyang Technological University, University of Michigan, Chongqing University of Arts and Sciences, and sponsored by National Natural Science Foundation of China (NSFC). The objective of IMS 2012 is to facilitate an exchange of information on best practices for the latest research advances in a range of areas. Informatics and Management Science contains over 600 contributions to suggest and inspire solutions and methods drawing from multiple disciplines including: ·         Computer Science ·         Communications and Electrical Engineering ·         Management Science ·         Service Science ·         Business Intelligence

  6. International Conference on Informatics and Management Science (IMS) 2012

    CERN Document Server

    Informatics and Management Science VI

    2013-01-01

    The International Conference on Informatics and Management Science (IMS) 2012 will be held on November 16-19, 2012, in Chongqing, China, which is organized by Chongqing Normal University, Chongqing University, Shanghai Jiao Tong University, Nanyang Technological University, University of Michigan, Chongqing University of Arts and Sciences, and sponsored by National Natural Science Foundation of China (NSFC). The objective of IMS 2012 is to facilitate an exchange of information on best practices for the latest research advances in a range of areas. Informatics and Management Science contains over 600 contributions to suggest and inspire solutions and methods drawing from multiple disciplines including: ·         Computer Science ·         Communications and Electrical Engineering ·         Management Science ·         Service Science ·         Business Intelligence

  7. Successful performances of the EU-AltTF sample, a large size Nb{sub 3}Sn cable-in-conduit conductor with rectangular geometry

    Energy Technology Data Exchange (ETDEWEB)

    Della Corte, A; Corato, V; Di Zenobio, A; Fiamozzi Zignani, C; Muzzi, L; Polli, G M; Reccia, L; Turtu, S [Associazione EURATOM-ENEA sulla Fusione, Via E Fermi 45, 00044 Frascati, Rome (Italy); Bruzzone, P [EPFL-CRPP, Fusion Technology, 5232 Villigen PSI (Switzerland); Salpietro, E [European Fusion Development Agreement, Close Support Unit, Boltzmannstrasse 2, 85748 Garching (Germany); Vostner, A, E-mail: antonio.dellacorte@enea.i [Fusion for Energy, c/ Josep Pla 2, Edificio B3, 08019 Barcelona (Spain)

    2010-04-15

    One of the design features which yet offers interesting margins for performance optimization of cable-in-conduit conductors (CICCs), is their geometry. For relatively small size Nb{sub 3}Sn CICCs, operating at high electromagnetic pressure, such as those for the EDIPO project, it has been experimentally shown that a design based on a rectangular layout with higher aspect ratio leads to the best performance, especially in terms of degradation with electromagnetic loads. To extend this analysis to larger size Nb{sub 3}Sn CICCs, we manufactured and tested, in the SULTAN facility, an ITER toroidal field (TF) cable, inserted into a thick stainless steel tube and then compacted to a high aspect ratio rectangular shape. Besides establishing a new record in Nb{sub 3}Sn CICC performances for ITER TF type cables, the very good test results confirmed that the conductor properties improve not only by lowering the void fraction and raising the cable twist pitch, as already shown during the ITER TFPRO and the EDIPO test campaigns, but also by the proper optimization of the conductor shape with respect to the electromagnetic force distribution. The sample manufacturing steps, along with the main test results, are presented here.

  8. [Christian Westerhoff. Zwangsarbeit im Ersten Weltkrieg. Deutsche Arbeitskräftepolitik im besetzten Polen und Litauen 1914-1918, Tilman Plath.Zwischen Schonung und Menschenjagden. Die Arbeitseinsatzpolitik in den baltischen Generalbezirken des Reich

    Index Scriptorium Estoniae

    Hiio, Toomas, 1965-

    2014-01-01

    Arvustus: Westerhoff, Christian. Zwangsarbeit im Ersten Weltkrieg. Deutsche Arbeitskräftepolitik im besetzten Polen und Litauen 1914-1918 (Studien zur historischen Migrationsforschung, 25). Verlag Ferdinand Schöningh. Padeborn 2011

  9. World-wide developments in motor vehicle inspection/maintenance (I/M) programs

    Energy Technology Data Exchange (ETDEWEB)

    Klausmeier, R. [Consulting Inc., Austin, TX (United States); Kishan, S. [Radian Corporation, Austin, TX (United States)

    1995-12-31

    Motor vehicles contribute much to urban air pollution. As a result, most governments have enacted emission standards that significantly lower pollutant emission levels from new motor vehicles. For example, vehicles built in the United States emit 95 % fewer pollutants than uncontrolled vehicles when they are new. However, studies indicate that proper maintenance is needed to obtain the full benefit of vehicle emission controls. Furthermore, there is evidence that a significant percentage of the vehicle fleet is not properly maintained. This has led to the creation of motor vehicle Inspection/Maintenance (I/M) Programs. I/M programs inspect vehicles for indications that they are emitting excessive quantities of pollutants. Vehicles that fail the inspection must be repaired in order to comply with program requirements. The first I/M programs were implemented in the United States in the early 1970s. With substantial urging from the federal government, most of the U.S. states with severe air pollution problems have implemented I/M programs. Recently, with the passage of the U.S. Clean Air Act Amendments of 1990, many states have been required to significantly upgrade the performance and coverage of their I/M programs. I/M programs also have been implemented in Europe and recently in Asia. This presentation reviews developments in I/M programs for light-duty gasoline powered vehicles. Developments in I/M programs for diesel powered vehicles are briefly described. (author)

  10. A flicker noise/IM3 cancellation technique for active mixer using negative impedance

    NARCIS (Netherlands)

    Cheng, W.; Annema, Anne J.; Wienk, Gerhardus J.M.; Nauta, Bram

    2013-01-01

    Abstract—This paper presents an approach to simultaneously cancel flicker noise and IM3 in Gilbert-type mixers, utilizing negative impedances. For proof of concept, two prototype double-balanced mixers in 0.16- m CMOS are fabricated. The first demonstration mixer chip was optimized for full IM3

  11. Real-time resource availability signalling in IMS-based networks

    NARCIS (Netherlands)

    Ozcelebi, T.; Radovanovic, I.; Lukkien, J.J.

    2007-01-01

    The emerging converged IP multimedia subsystem (IMS) allows the use of unlicensed, nondedicated and nondeterministic computer access networks for delivering IP multimedia services. To provide end-to-end quality-of-service (QoS) over such networks combined with the IMS core network, for resource

  12. IMS Intra- and Inter Domain End-to-End Resilience Analysis

    DEFF Research Database (Denmark)

    Kamyod, Chayapol; Nielsen, Rasmus Hjorth; Prasad, Neeli R.

    2013-01-01

    This paper evaluated resilience of the reference IMS based network topology in operation through the keys reliability parameters via OPNET. The reliability behaviors of communication within similar and across registered home IMS domains were simulated and compared. Besides, the reliability effects...

  13. Strukturwandel, Verbandsabstinenz, Tarifflucht : zur Lage der Unternehmen und Arbeitgeberverbände im ostdeutschen verarbeitenden Gewerbe

    OpenAIRE

    Ettl, Wilfried; Heikenroth, André

    1996-01-01

    "Im Kontext der am Start der ostdeutschen Transformation vorgenommenen wirtschaftspolitischen Richtungsentscheidungen erwies sich die flächentarifvertragliche Normierung von Arbeits- und Entlohnungsbedingungen für die Arbeitgeberverbände als organisationspolitisch dysfunktional, weil sie der Differenzierung betriebswirtschaftlicher Kostenbedingungen und Interessenlagen im rasanten Strukturwandel nicht gerecht werden konnte. Anhand der Ergebnisse einer Befragung ostdeutscher ...

  14. NDIA 2018 IM and EM Technology Symposium: Innovative Insensitive Munition Solutions for Enhanced Warfighter Effectiveness

    Science.gov (United States)

    2018-04-26

    2018 IM & EM TECHNOLOGY SYMPOSIUM INNOVATIVE INSENSITIVE MUNITION SOLUTIONS FOR ENHANCED WARFIGHTER EFFECTIVENESS April 23 – 26, 2018 Doubletree by...IM & EM TECHNOLOGY SYMPOSIUM On behalf of the Insensitive Munitions and Energetic Materials Committee and our MSIAC partner, I would like to...welcome you to the 2018 Insensitive Munitions and Energetic Materials Technology Symposium. This international gathering of the top chemists, system

  15. World-wide developments in motor vehicle inspection/maintenance (I/M) programs

    Energy Technology Data Exchange (ETDEWEB)

    Klausmeier, R [Consulting Inc., Austin, TX (United States); Kishan, S [Radian Corporation, Austin, TX (United States)

    1996-12-31

    Motor vehicles contribute much to urban air pollution. As a result, most governments have enacted emission standards that significantly lower pollutant emission levels from new motor vehicles. For example, vehicles built in the United States emit 95 % fewer pollutants than uncontrolled vehicles when they are new. However, studies indicate that proper maintenance is needed to obtain the full benefit of vehicle emission controls. Furthermore, there is evidence that a significant percentage of the vehicle fleet is not properly maintained. This has led to the creation of motor vehicle Inspection/Maintenance (I/M) Programs. I/M programs inspect vehicles for indications that they are emitting excessive quantities of pollutants. Vehicles that fail the inspection must be repaired in order to comply with program requirements. The first I/M programs were implemented in the United States in the early 1970s. With substantial urging from the federal government, most of the U.S. states with severe air pollution problems have implemented I/M programs. Recently, with the passage of the U.S. Clean Air Act Amendments of 1990, many states have been required to significantly upgrade the performance and coverage of their I/M programs. I/M programs also have been implemented in Europe and recently in Asia. This presentation reviews developments in I/M programs for light-duty gasoline powered vehicles. Developments in I/M programs for diesel powered vehicles are briefly described. (author)

  16. Calibración de imágenes de radares meteorológicos

    Directory of Open Access Journals (Sweden)

    Virgilio Santander Socorras Quintero

    2014-04-01

    Full Text Available En este documento se ilustran las técnicas de fusión de imágenes para complementar y calibrar la información meteorológica presente en imágenes de radares terrestres con el uso de imágenes satelitales meteorológicas. Para realizar la calibración de las imágenes de radares terrestres se implementó un método de fusión de imágenes basado en la herramienta matemática transformada wavelet discreta. Ya que existe una familia de wavelets, es necesario determinar cuál wavelet ofrece el mejor resultado; para esto se determina la correlación existente entre los resultados de fusión de diferentes wavelets y las imágenes uti-lizadas en cada fusión. Se define una metodología para selección de umbral global de segmentación y una metodología para realizar la calibración de las imágenes de radares terrestres. Siguiendo la metodología de calibración de imágenes, se generan algunos resultados y se muestran sus ventajas.

  17. Computer-Aided Teaching Using MATLAB/Simulink for Enhancing an IM Course With Laboratory Tests

    Science.gov (United States)

    Bentounsi, A.; Djeghloud, H.; Benalla, H.; Birem, T.; Amiar, H.

    2011-01-01

    This paper describes an automatic procedure using MATLAB software to plot the circle diagram for two induction motors (IMs), with wound and squirrel-cage rotors, from no-load and blocked-rotor tests. The advantage of this approach is that it avoids the need for a direct load test in predetermining the IM characteristics under reduced power.…

  18. A Unidimensional Instrument for Measuring Internal Marketing Concept in the Higher Education Sector: IM-11 Scale

    Science.gov (United States)

    Yildiz, Suleyman Murat; Kara, Ali

    2017-01-01

    Purpose: Although the existing internal marketing (IM) scales include various scale items to measure employee motivation, they fall short of incorporating the needs and expectations of service sector employees. Hence, the purpose of this study is to present a practical instrument designed to measure the IM construct in the higher education sector.…

  19. Long-term liablities of coal mining; Ewigkeitslasten im Kohlenbergbau

    Energy Technology Data Exchange (ETDEWEB)

    Frenz, Walter (ed.) [GDMB Gesellschaft der Metallurgen und Bergleute e.V., Clausthal-Zellerfeld (Germany)

    2016-07-01

    The closer the end of coal mining in 2018, the more the issue of groundwater re-emergence in the Ruhr area is also being considered. This is especially the case because currently the subject of restitution and liability issues in the area of contaminated sites of the peaceful use of nuclear energy is discussed. In addition, the companies concerned lost considerable value on the stock market. For this reason, the question of whether the financial provisions in the created foundation are sufficient to shoulder the expected responsibilities and measures also arises with regard to coal mining. The question is which measures are to be taken and where damages can occur. Additional impulses are given by the Meggen judgment of the BVerwG of 18.12.2014, which interpreted the responsibility of the mining companies very widely. In the Rhineland, an earthquake hit 2.4 on 22.12.2015 - probably due to a rise in groundwater around the closed opencast mine Bergheim. All these questions are included in the colloquium on economics and environmental law on 26 January 2016. This also includes experiences and problems from other federal states such as Brandenburg and Saxony. [German] Je naeher das Ende des Steinkohlenbergbaus 2018 rueckt, desto eher geraet auch die Frage des Grundwasserwiederanstiegs im Ruhrgebiet ins Blickfeld. Das gilt zumal deshalb, weil aktuell ueber Rueckstellung und Haftungsfragen im Bereich der Altlasten der friedlichen Nutzung der Kernenergie diskutiert wird. Zudem verloren die betroffenen Gesellschaften an der Boerse erheblich an Wert. Daher stellt sich auch in Bezug auf den Steinkohlenbergbau die Frage, ob die finanziellen Rueckstellungen in der geschaffenen Stiftung ausreichen, um die zu erwartenden Verantwortlichkeiten und Massnahmen schultern zu koennen. Vorgelagert ist die Frage, welche Massnahmen zu ergreifen sind und wo Schaeden auftreten koennen. Zusaetzliche Impulse bekommt diese Frage durch das Meggen-Urteil des BVerwG vom 18.12.2014, welches die

  20. Biomechanisch-kinemetrische Bewegungsanalyse und Ansätze zur Bewegungssteuerung für ein Training im Wellenreiten

    OpenAIRE

    Matschkur, Tina

    2008-01-01

    Neben der biomechanisch-kinemetrischen Bewegungsanalyse einzelner ausgewählter Techniken im Wellenreiten beschäftigt sich diese Dissertation auch ansatzweise im Rahmen einer elektromyographischen Fallstudie mit der muskulären Koordination bei der Bewegungsausführung im Surfen, um daraus Schlussfolgerungen für das Training im Wellenreiten treffen zu können. Ein geschichtlicher und wissenschaftlicher Überblick über das Wellenreiten leitet das Thema ein und macht somit auf die besondere Ausgangs...

  1. ODE/IM correspondence and the Argyres-Douglas theory

    Science.gov (United States)

    Ito, Katsushi; Shu, Hongfei

    2017-08-01

    We study the quantum spectral curve of the Argyres-Douglas theories in the Nekrasov-Sahashvili limit of the Omega-background. Using the ODE/IM correspondence we investigate the quantum integrable model corresponding to the quantum spectral curve. We show that the models for the A 2 N -type theories are non-unitary coset models ( A 1)1 × ( A 1) L /( A 1) L+1 at the fractional level L=2/2N+1-2 , which appear in the study of the 4d/2d correspondence of N = 2 superconformal field theories. Based on the WKB analysis, we clarify the relation between the Y-functions and the quantum periods and study the exact Bohr-Sommerfeld quantization condition for the quantum periods. We also discuss the quantum spectral curves for the D and E type theories.

  2. Think tank in the desert sand; Ideenschmiede im Wuestensand

    Energy Technology Data Exchange (ETDEWEB)

    Ullrich, Sven

    2013-11-01

    The international architectural competition shows imaginative concepts for living in energy self-sufficient houses. A total of 109 student teams had applied. Only 19 were allowed to build their solar house in Irvine, California. In addition to architectural elements and an attractive design, the jury members also evaluate the technical concepts of the buildings. The winners came from Austria with their building ''Lisi''. [German] Der internationale Architekturwettbewerb zeigt ideenreiche Konzepte zum Wohnen in energieautarken Haeusern. Insgesamt 109 Studenten-Teams hatten sich beworben. Nur 19 durften ihr Solarhaus im kalifornischen Irvine aufbauen. Neben architektonischen Elementen und einem attraktiven Design bewerten die Jurymitglieder auch die Technikkonzepte der Gebaeude. Die Gewinner kamen aus Oesterreich mit ihrem Gebaeude ''Lisi''.

  3. Berechnung verkehrlicher Substitutionseffekte im Personenverkehr bei Online-Shopping

    Science.gov (United States)

    Nerlich, Mark R.; Schiffner, Felix; Vogt, Walter; Rauh, Jürgen; Breidenbach, Petra

    Für Güter des täglichen, mittelfristigen und langfristigen Bedarfs sowie für das Beispiel Baumarktartikel wird das Potenzial für Personenverkehrsaufwand von Einkaufsaktivtäten quantitativ abgeschätzt. Die entwickelten Algorithmen behandeln die einkaufsvorbereitende Information und den eigentlichen Einkauf, d.h. den Erwerb eines Gutes, separat. Informationsaktivitäten haben insbesondere bei höherwertigen Gütern einen hohen Stellenwert und damit auch verkehrliche Relevanz. Wie Berechnungen zeigen, spart Online-Shopping Informations- und Einkaufsverkehrsaufwand im Pkw-Verkehr ein. Die notwendigen Eingangsdaten wie differenzierte Informations- und Einkaufshäufigkeiten sowie verkehrliche Parameter zu Verkehrsmittelwahl, Entfernungen und Wegekopplungen wurden aus eigenen Erhebungen gewonnen.

  4. Disturbance observer based current controller for vector controlled IM drives

    DEFF Research Database (Denmark)

    Teodorescu, Remus; Dal, Mehmet

    2008-01-01

    induction motor (IM) drives. The control design, based on synchronously rotating d-q frame model of the machine, has a simple structure that combines the proportional portion of a conventional PI control and output of the observer. The observer is predicted to estimate the disturbances caused by parameters...... coupling effects and increase robustness against parameters change without requiring any other compensation strategies. The experimental implementation results are provided to demonstrate validity and performance of the proposed control scheme.......In order to increase the accuracy of the current control loop, usually, well known parameter compensation and/or cross decoupling techniques are employed for advanced ac drives. In this paper, instead of using these techniques an observer-based current controller is proposed for vector controlled...

  5. Single-molecule studies of the Im7 folding landscape.

    Science.gov (United States)

    Pugh, Sara D; Gell, Christopher; Smith, D Alastair; Radford, Sheena E; Brockwell, David J

    2010-04-23

    Under appropriate conditions, the four-helical Im7 (immunity protein 7) folds from an ensemble of unfolded conformers to a highly compact native state via an on-pathway intermediate. Here, we investigate the unfolded, intermediate, and native states populated during folding using diffusion single-pair fluorescence resonance energy transfer by measuring the efficiency of energy transfer (or proximity or P ratio) between pairs of fluorophores introduced into the side chains of cysteine residues placed in the center of helices 1 and 4, 1 and 3, or 2 and 4. We show that while the native states of each variant give rise to a single narrow distribution with high P values, the distributions of the intermediates trapped at equilibrium (denoted I(eqm)) are fitted by two Gaussian distributions. Modulation of the folding conditions from those that stabilize the intermediate to those that destabilize the intermediate enabled the distribution of lower P value to be assigned to the population of the unfolded ensemble in equilibrium with the intermediate state. The reduced stability of the I(eqm) variants allowed analysis of the effect of denaturant concentration on the compaction and breadth of the unfolded state ensemble to be quantified from 0 to 6 M urea. Significant compaction is observed as the concentration of urea is decreased in both the presence and absence of sodium sulfate, as previously reported for a variety of proteins. In the presence of Na(2)SO(4) in 0 M urea, the P value of the unfolded state ensemble approaches that of the native state. Concurrent with compaction, the ensemble displays increased peak width of P values, possibly reflecting a reduction in the rate of conformational exchange among iso-energetic unfolded, but compact conformations. The results provide new insights into the initial stages of folding of Im7 and suggest that the unfolded state is highly conformationally constrained at the outset of folding. (c) 2010 Elsevier Ltd. All rights reserved.

  6. Zur Palökologie der Euproopiden im Nordwestdeutschen Oberkarbon

    Directory of Open Access Journals (Sweden)

    S. Schultka

    2000-01-01

    Full Text Available Tierische Fossilien aus dem Westfal D des Piesbergs bei Osnabrück sind seit 1860 vereinzelt immer wieder beschrieben worden. Doch erst durch die Funde der letzten 30 Jahre zählt der Piesberg zu den bedeutendsten Fundorten terrestrischer Fauna im Karbon. Erstmals werden 45 stratifiziert aufgesammelte Individuen von Euproops untersucht. Einige Details der Morphologie sowie eine dichte Behaarung werden beschrieben. Auf der Basis dieser Merkmale sowie der Verteilung juveniler und adulter Individuen im geologischen Profil wird eine Deutung des Lebensraumes der Euproopiden versucht. Danach hielten sich die juvenilen Individuen dieser Tiergruppe als Laubstreubewohner in feuchten Spülsäumen flacher ruhiger Gewässer und Laubstreuhorizonten auf. Die adulten Formen lebten vornehmlich benthisch in ufernahen Gewässern und verließen wohl nur noch gelegentlich das Wasser. Since 1860 articulated fossils of terrestrial taxa have been described from lower Westfalian D sediments of the Piesberg section near Osnabrück (northwestern Germany. In this paper 45 individuals of the genus Euproops, sampled from particular levels in the profile, are reported on for the first time. Analysis of the fossil material reveals new morphological details – especially setae densely covering the ventral side – that, combined with the geological setting of the profile, gives novel insights into the palaeoenvironment and to the hypothesis of subaerial activity. Young individuals of Euproops may have been "litter dwellers" inhabiting forest-litter and partly decayed plant material that had washed ashore. By contrast, adults formed a principal component of the nearshore benthic fauna. They were able to leave the water, but only for short periods. This is proved by the occurence of adults and juveniles in different lithologies. doi:10.1002/mmng.20000030105

  7. 78 FR 79498 - Notice Pursuant to The National Cooperative Research and Production Act of 1993-IMS Global...

    Science.gov (United States)

    2013-12-30

    ... Production Act of 1993--IMS Global Learning Consortium, Inc. Notice is hereby given that, on November 22....C. Sec. 4301 et seq. (``the Act''), IMS Global Learning Consortium, Inc. (``IMS Global'') has filed..., Carson-Dellosa Publishing, Greensboro, NC; Data Recognition Group, Maple Grove, MN; Nelson Education Ltd...

  8. 78 FR 7456 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-IMS Global...

    Science.gov (United States)

    2013-02-01

    ... District, Selbyville, DE; learning.com , Portland, OR; State of Michigan Dept. of Education, Bureau of... Production Act of 1993--IMS Global Learning Consortium, Inc. Notice is hereby given that, on December 28....C. 4301 et seq. (``the Act''), IMS Global Learning Consortium, Inc. (``IMS Global'') has filed...

  9. [Glanz und Elend - Mythos und Wirklichkeit der Herrenhäuser im Baltikum] / Karsten Brüggemann

    Index Scriptorium Estoniae

    Brüggemann, Karsten, 1965-

    2014-01-01

    Arvustus: Glanz und Elend - Mythos und Wirklichkeit der Herrenhäuser im Baltikum. Hrsg. von Ilse von zur Mühlen im Auftrag der Carl-Schirren-Gesellschaft e.V. und des Ostpreußischen Landesmuseums Lüneburg. Kunstverlag Josef Fink. Lindenberg im Allgäu 2012

  10. IMS Learning Design desde dentro. Una especificación para crear escenarios de aprendizaje online (parte I)

    NARCIS (Netherlands)

    Burgos, Daniel; Berbegal, Nidia; Griffiths, David; Tattersall, Colin; Koper, Rob

    2005-01-01

    IMS Learning Design, IMS LD de ahora en adelante (IMS, 2003), es una especificación centrada en formación online o e-learning y que permite modelar programaciones curriculares o lecciones presenciales de forma que puedan ser seguidas online, construyendo lo que se denomina Unidades de Aprendizaje

  11. Discussion of the concept of safety indicators from the point of view of TfUX2 accident sequence for Forsmark 3

    International Nuclear Information System (INIS)

    Bujor, A.

    1991-01-01

    This paper contains general considerations on the safety indicators, with details at the system level and for the operator actions. For the system analysis, a modular analysis at a low detailed level is proposed (Module System Approach) in order to emphasize the safety related aspects at the subsystem (module) level. The operator actions are divided in ''active actions'' (actions in the control room during incident/accident situations) and ''passive actions'' (actions during tests, maintenance, repairs, etc.) and are analysed separately. In the second part, a discussion of a possible way to apply some SI to the TfUX2 accident sequence for FORSMARK-3, is done. For the analysis of the Auxiliary Feedwater Systems (AFWS) an equation is proposed to derive target values for the failure probability on demand at the train level, given the target value at the system level, including the common cause failures between the redundant trains. (author) 6 tabs., 18 refs

  12. Loss of Function of the Nuclear Receptor NR2F2, Encoding COUP-TF2, Causes Testis Development and Cardiac Defects in 46,XX Children

    DEFF Research Database (Denmark)

    Bashamboo, Anu; Eozenou, Caroline; Jorgensen, Anne

    2018-01-01

    Emerging evidence from murine studies suggests that mammalian sex determination is the outcome of an imbalance between mutually antagonistic male and female regulatory networks that canalize development down one pathway while actively repressing the other. However, in contrast to testis formation......, the gene regulatory pathways governing mammalian ovary development have remained elusive. We performed exome or Sanger sequencing on 79 46,XX SRY-negative individuals with either unexplained virilization or with testicular/ovotesticular disorders/differences of sex development (TDSD/OTDSD). We identified...... tissue. We demonstrate a highly significant association between the NR2F2 loss-of-function mutations and this syndromic form of DSD (p = 2.44 × 10-8). We show that COUP-TF2 is highly abundant in a FOXL2-negative stromal cell population of the fetal human ovary. In contrast to the mouse, these data...

  13. Transverse heat transfer coefficient in the dual channel ITER TF CICCs Part II. Analysis of transient temperature responses observed during a heat slug propagation experiment

    Science.gov (United States)

    Lewandowska, Monika; Herzog, Robert; Malinowski, Leszek

    2015-01-01

    A heat slug propagation experiment in the final design dual channel ITER TF CICC was performed in the SULTAN test facility at EPFL-CRPP in Villigen PSI. We analyzed the data resulting from this experiment to determine the equivalent transverse heat transfer coefficient hBC between the bundle and the central channel of this cable. In the data analysis we used methods based on the analytical solutions of a problem of transient heat transfer in a dual-channel cable, similar to Renard et al. (2006) and Bottura et al. (2006). The observed experimental and other limits related to these methods are identified and possible modifications proposed. One result from our analysis is that the hBC values obtained with different methods differ by up to a factor of 2. We have also observed that the uncertainties of hBC in both methods considered are much larger than those reported earlier.

  14. Doing religion im Phowa-Kurs: Praxeologische und reflexionslogische Studien zum "bewussten Sterben" im Diamantweg-Buddhismus

    Directory of Open Access Journals (Sweden)

    Werner Vogd

    2015-07-01

    Full Text Available Im Sinne einer pragmatistischen Perspektive, wie sie zuerst John DEWEY (1987 [1934] in Anschluss an William JAMES formulierte, ist das Religiöse weniger als eine spezifische Art von experience zu verstehen, denn als ein adjustment hin zu einer epistemischen Perspektive, die alle Erfahrungen in einem veränderten Licht erscheinen lässt. Religiosität zielt damit auf ein besonderes Selbst- und Weltverhältnis, in dem die Beziehung zwischen Selbst und Welt aus einer ganzheitlichen Perspektive betrachtet wird. Wie aber können fremde, auf den ersten Blick in ihrer Genese unwahrscheinliche und unter modernen Verhältnissen zudem anzweifelbare religiöse Haltungen und Sinnsysteme etabliert werden? Am Beispiel der im tibetischen Buddhismus verbreiteten Phowa-Meditation des "bewussten Sterbens" wird untersucht, wie für westliche Adept/innen auf den ersten Blick befremdlich und esoterisch anmutende spirituelle Lehren mit zunehmender Praxis an Evidenz und Sinnhaftigkeit gewinnen können, indem sich Gruppenprozesse, Visualisierungen, körperorientierte Übungen und psychisches Erleben zu einem übergreifenden Arrangement verschränken. Die empirische Datengrundlage für die Untersuchung liefern narrative Interviews mit westlich sozialisierten Schüler/innen und Lehrer/innen des Diamantweg-Buddhismus, der derzeit größten buddhistischen Gemeinschaft des tibetischen Buddhismus in Deutschland. Die Auswertung der Interviews erfolgte angelehnt an die dokumentarische Methode, erweitert durch eine Kontexturanalyse, um den Reflexionsverhältnissen gerecht zu werden, die den religiösen Selbst- und Weltbezug aufspannen. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1503179

  15. Comparison of different tube-of-response (TOR) models for resolution recovery in PET image reconstruction for the Philips Ingenuity TF PET/MR

    Energy Technology Data Exchange (ETDEWEB)

    Lougovski, Alexandr; Hofheinz, Frank; Van Den Hoff, Jorg [Helmholtz-Center Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, PET Center, Dresden (Germany)

    2015-05-18

    Recently, we have proposed a method for on-the-fly system matrix computation where the tube-of-response (TOR) is approximated as a cylinder with constant density (TORCD) and the cubic voxels are replaced by spheres. We could show that with this model the PET image quality can be notably improved compared to the vendor provided image reconstruction of our Philips Ingenuity-TF PET/MR. In this work we address the question whether image quality can be further improved by using a variable density TOR (TOR-VD). The radial variability of TOR-VD was modelled by a Kaiser-Bessel function. Free parameters of this density model were used to optimize image properties regarding resolution, noise, and Gibbs artifacts. Additional, a TOR-VD model accounting for position dependent effects along the TOR caused by the finite solid angles of the detectors is under investigation. Phantom measurement were performed with a Philips Ingenuity-TF PET/MR scanner. Listmode data were reconstructed using TOR-CD and TORVD, respectively on two different grids with cubic voxel size of 2 mm and 4 mm. Image quality was assessed with resolution-noise curves and investigation of the radial position dependence of the spatial resolution. For 2 mm voxels, TOR-VD consistently yields a slight improvement of the investigated image quality measures compared to TOR-CD. For 4 mm voxels both models lead essentially to the same results. These findings can be understood as a consequence of the relative size of voxel and TOR. For typical whole body studies (4 mm voxel size) a variable TOR does not improve image quality beyond what is achievable with a constant density TOR. For smaller voxel size the image quality can indeed be somewhat improved with a variable TOR but at the expense of drastically increased computation time.

  16. High-pressure solubility of carbon dioxide in pyrrolidinium-based ionic liquids: [bmpyr][dca] and [bmpyr][Tf{sub 2}N

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byung-Chul; Nam, Sang Gyu [Hannam University, Daejeon (Korea, Republic of)

    2015-03-15

    Solubility data of carbon dioxide (CO{sub 2}) in two pyrrolidinium-based ionic liquids: 1-butyl-1-methylpyrrolidinium dicyanamide ([bmpyr][dca]) and 1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide ([bmpyr] [Tf{sub 2}N]) are presented at pressures up to about 30MPa and temperatures from 303..2 K to 343.2 K. The solubility was determined by measuring bubble or cloud point pressures of mixtures of CO{sub 2} and ionic liquid using a high-pressure equilibrium apparatus equipped with a variable-volume view cell. The CO{sub 2} solubility in the ionic liquid in terms of the mole fraction or the molality increased with the increase of the equilibrium pressure at a given temperature, but decreased with the increase of temperature at a given pressure. At a given temperature, the mole fraction of CO{sub 2} dissolved in the ionic liquid increased rapidly as pressure increased. CO{sub 2} solubility in the mole fraction almost reached saturation around 0.65 for [bmpyr][dca] and around 0..8 for [bmpyr][Tf{sub 2}N], respectively. The experimental data for the CO{sub 2}+ionic liquid systems were correlated using the Peng-Robinson equation of state (PR-EoS). The mixing rules of the Wong-Sandler type rather than the classical mixing rules of the van der Waals type were coupled with the PR-EoS. The resulting modeling approach proved to be able to correlate the CO{sub 2} solubilities in aforementioned ionic liquids over the aforementioned range of temperature and pressure within 5% average deviations.

  17. Comparison of different tube-of-response (TOR) models for resolution recovery in PET image reconstruction for the Philips Ingenuity TF PET/MR

    International Nuclear Information System (INIS)

    Lougovski, Alexandr; Hofheinz, Frank; Van Den Hoff, Jorg

    2015-01-01

    Recently, we have proposed a method for on-the-fly system matrix computation where the tube-of-response (TOR) is approximated as a cylinder with constant density (TORCD) and the cubic voxels are replaced by spheres. We could show that with this model the PET image quality can be notably improved compared to the vendor provided image reconstruction of our Philips Ingenuity-TF PET/MR. In this work we address the question whether image quality can be further improved by using a variable density TOR (TOR-VD). The radial variability of TOR-VD was modelled by a Kaiser-Bessel function. Free parameters of this density model were used to optimize image properties regarding resolution, noise, and Gibbs artifacts. Additional, a TOR-VD model accounting for position dependent effects along the TOR caused by the finite solid angles of the detectors is under investigation. Phantom measurement were performed with a Philips Ingenuity-TF PET/MR scanner. Listmode data were reconstructed using TOR-CD and TORVD, respectively on two different grids with cubic voxel size of 2 mm and 4 mm. Image quality was assessed with resolution-noise curves and investigation of the radial position dependence of the spatial resolution. For 2 mm voxels, TOR-VD consistently yields a slight improvement of the investigated image quality measures compared to TOR-CD. For 4 mm voxels both models lead essentially to the same results. These findings can be understood as a consequence of the relative size of voxel and TOR. For typical whole body studies (4 mm voxel size) a variable TOR does not improve image quality beyond what is achievable with a constant density TOR. For smaller voxel size the image quality can indeed be somewhat improved with a variable TOR but at the expense of drastically increased computation time.

  18. Cerebellar oxidative DNA damage and altered DNA methylation in the BTBR T+tf/J mouse model of autism and similarities with human post mortem cerebellum.

    Directory of Open Access Journals (Sweden)

    Svitlana Shpyleva

    Full Text Available The molecular pathogenesis of autism is complex and involves numerous genomic, epigenomic, proteomic, metabolic, and physiological alterations. Elucidating and understanding the molecular processes underlying the pathogenesis of autism is critical for effective clinical management and prevention of this disorder. The goal of this study is to investigate key molecular alterations postulated to play a role in autism and their role in the pathophysiology of autism. In this study we demonstrate that DNA isolated from the cerebellum of BTBR T+tf/J mice, a relevant mouse model of autism, and from human post-mortem cerebellum of individuals with autism, are both characterized by an increased levels of 8-oxo-7-hydrodeoxyguanosine (8-oxodG, 5-methylcytosine (5mC, and 5-hydroxymethylcytosine (5hmC. The increase in 8-oxodG and 5mC content was associated with a markedly reduced expression of the 8-oxoguanine DNA-glycosylase 1 (Ogg1 and increased expression of de novo DNA methyltransferases 3a and 3b (Dnmt3a and Dnmt3b. Interestingly, a rise in the level of 5hmC occurred without changes in the expression of ten-eleven translocation expression 1 (Tet1 and Tet2 genes, but significantly correlated with the presence of 8-oxodG in DNA. This finding and similar elevation in 8-oxodG in cerebellum of individuals with autism and in the BTBR T+tf/J mouse model warrant future large-scale studies to specifically address the role of OGG1 alterations in pathogenesis of autism.

  19. Nachlassverzeichnisse im Netz – Ein Projekt der Bayerischen Staatsbibliothek

    Directory of Open Access Journals (Sweden)

    Maximilian Schreiber

    2015-12-01

    Full Text Available Nachlässe rücken in der wissenschaftlichen Forschung immer mehr in den Fokus, wie etwa die stark gestiegenen Nutzerzahlen der Bayerischen Staatsbibliothek (BSB über die letzten Jahre hinweg deutlich zeigen. Umso wichtiger ist insbesondere für Bibliotheken mit umfangreichen und fachlich breit gestreuten Nachlassbeständen eine möglichst genaue Erschließung im Internet, um der wissenschaftlichen Forschung einen schnellen Zugriff auf diese unikalen Materialien zu ermöglichen. Bei der digitalen Bereitstellung und vernetzten Erschließung verfolgt die BSB mit ihren rund 1.100 Nachlässen eine doppelte Strategie. Einerseits wird versucht, ausgewählte Nachlässe im Verbundsystem Kalliope zu katalogisieren. Andererseits werden die Erschließungsdaten zu den bereits erschlossenen und den erst grob geordneten Nachlässen, die in Form von hand- oder maschinenschriftlichen Listen sowie als Wordlisten vorliegen, digitalisiert und über den Bibliothekskatalog online zur Verfügung gestellt, um den Nutzern die Möglichkeit zu geben, sich so über die vorhandenen Bestände zu informieren. Wie dieses Projekt genau durchgeführt wurde, ist Gegenstand des Artikels. Special collections and personal papers are becoming more and more important for academic research, as is shown clearly by the increasing usage numbers at the Bavarian State Library (BSB over the last couple of years. Especially for libraries with extensive and manifold collections of estates, it is important to present these unique materials in a well-indexed manner on the internet, in order to give the scientific community easy access. The Bavarian State Library, which keeps more than 1.100 estates of personal papers, pursues a double strategy: On the one hand, selected estates are fully cataloged in the database “Kalliope”. As this procedure is likely to take a long time, the library on the other hand has been digitizing older hand- or typewritten lists with information

  20. Workflows des Projektes Mengenentsäuerung im Deutschen Literaturarchiv

    Directory of Open Access Journals (Sweden)

    Melanie Kubitza

    2018-03-01

    Full Text Available Das Deutsche Literaturarchiv Marbach (DLA begann 1998 mit der Evaluation geeigneter Entsäuerungsverfahren für seine unikalen Archiv- und Bibliotheksbestände. Seit 2013 erfolgt eine kontinuierliche Entsäuerungsbehandlung der Buchbestände mit dem Papersave-Verfahren der Nitrochemie AG, mit einer jährlichen Entsäuerungsleistung von insgesamt rund 4,0 t in acht Chargen. Neben den Magazinbeständen mit Erstausgaben bis hin zur Sekundärliteratur zu den einzelnen Autoren, wurden nun auch erstmals erfolgreich Bände aus den Spezialsammlungen des DLA entsäuert, zu denen auch Autorenbibliotheken gehören. Der Beitrag erläutert neben der Zusammenarbeit des Referats Bestandserhaltung mit den Abteilungen Bibliothek und Archiv auch Teilaspekte der Workflows aus restauratorischer Sicht. Dabei steht die intern entwickelte Barcode-unterstützte Dokumentation der Maßnahme auf Exemplarsebene im Bestandskatalog Kallías im Fokus. Sie enthält neben den verfahrensrelevanten Daten u. a. Informationen zu den Ausschlusskriterien oder alternativen und ergänzenden Maßnahmen der Verpackung, Restaurierung oder Digitalisierung. Das Marbacher Mengenentsäuerungsprojekt führt an den Originalen eine Qualitätskontrolle bezüglich aufgetretener Nebenwirkungen am Bibliotheksgut durch und kontrolliert die Langzeitwirkung der Entsäuerung an originalähnlichen Referenzbänden mit nicht zerstörungsfreien Messungen. In 1998 the German Literature Archive (DLA began to evaluate appropriate deacidification processes for its unique archive and library stock. Since 2013, Nitrochemie’s papersave procedure has been used for an ongoing deacidification treatment of the bookstock with an annual output of about 4,0 t in eight batches. The deacidification process has been successfully used for primary and secondary literature as well as - for the first time - for volumes of the rare materials collection of the DLA, including authors‘ libraries. The article describes the

  1. Hochtemperatur-Kernkraftwerk GmbH (HKG). Annual report 1985

    International Nuclear Information System (INIS)

    1986-01-01

    The annual report presents the agenda of the general meeting of members, held on July 3, 1986 at Hamm-Uentrop, the report of the managing board, and the annual financial statement as of December 31, 1985, including the profit and loss account of the period January 1 to December 31, 1985. The object of the HKG GmbH is the planning, financing, installation, and operation of the Hamm-Uentrop nuclear power station equipped with a high-temperature reactor, as a joint enterprise of the European partners. (UA) [de

  2. Publication concerning licensing notices for the Kernkraftwerk Kruemmel

    International Nuclear Information System (INIS)

    1977-01-01

    The 3rd supplement to the 2nd partial licence sector concerns the change of concept regarding the scram system by going over from the scram collecting tank system to the individual tank system. The 7th partial licence notice refers to the construction of 1) the control rod drive and the scram system including the related operational controls; 2) the emergency power diesel aggregates; 3) the condensation pipe transverse system (transverse system in the condensation chamber). (orig./HP) [de

  3. Kernkraftwerk Obrigheim (KWO) GmbH. Annual report 1991

    International Nuclear Information System (INIS)

    Koerner, C.

    1992-01-01

    The Obrigheim nuclear power station was operated at full load from August 21 through Dec. 31, 1991, generating 1.108 GWh of electrical energy in 3.186 operating hours. The Obrigheim nuclear power station thus achieved during this period of 133 days in 1991 an operating availability of 100%. Since its commissioning in October 1968, the Obrigheim reactor station has been operating for 161.527 hours, generating 54.409 GWh (gross), and from test operation started in March 1969 up to the end of 1991, all in all 54.284 GWh have been generated in 160.747 operating hours, which means an availability time ratio of 78.2%, and a capacity factor of 80.4%. The plant was shut down in 1991 for the 21st refuelling operation including inspection and repair work, for a fictitious period of 1783 hours. In addition, power operation was stopped by an order of the supervisory authority for another 3.791 hours, so that the plant remained disconnected from the grid between Januar 1 and August 8, 1991. In the last part of the year 1991, until May 26, the plant had an excellent availability time ratio and thus contributed about 2.5% of the safe, economic and environmentally sound electricity supplies in Baden-Wuerttemberg. (orig.) [de

  4. Kernkraftwerk Obrigheim GmbH. Annual report 1989

    International Nuclear Information System (INIS)

    Koerner, C.

    1990-01-01

    The Obrigheim nuclear power station was operated at full load during the year 1989: 7.756 operating hours produced electrical energy of 2.689 GWh. This is the fifth best annual result during Obrigheim's operating period. Since commissioning in October 1968, 154.866 hours of operation have generated 52.125 GWh (gross) and from test operation in March 1969 until the end of 1989, 154.086 hours of operation have generated 52.013 GWh. This is an availability of power of 82.1% in this period and a time availability of 84.4%. In 1988, the plant was shut down for 927 hours for the 20th refueling including testing, inspection and repair work. Apart from refueling, the plant had a good time availability and therefore contributed 5% to the safe, economical and environmentally acceptable electricity supply of the Land Baden-Wuerttemberg. The power station is of great significance to the region, both in terms of power supply and the economy. (orig.) [de

  5. Annual report 1988 of the Kernkraftwerk Obrigheim GmbH

    International Nuclear Information System (INIS)

    Koerner, C.

    1989-01-01

    The Obrigheim nuclear power station was operated at full load during the year 1988; 7.800 operating hours produced electrical energy of 2.755 GWh. This is the second best annual result during Obrigheim's operating period. Since commissioning in October 1968, 147.110 hours of operation have generated 49.436 GWh (gross) and from test operation in March 1969 until the end of 1988, 146.330 hours of operation have generated 49.324 GWh. This is an availability of power of 81.9% in this period and a time availability of 84.1%. In 1988, the plant was shut down for 927 hours for the 18th refueling including testing, inspection and repair work. Apart from refueling, the plant had a good time availability and therefore contributed 5% to the safe, economical and environmentally acceptable electricity supply of the Land Baden-Wuerttemberg. The power station is of great significance to the region, both in terms of power supply and the economy. (orig./HP) [de

  6. Kernkraftwerk Obrigheim GmbH. Annual report 1990

    International Nuclear Information System (INIS)

    Koerner, C.

    1991-01-01

    The Obrigheim nuclear power station was operated at full load from January 1 through May 25, 1990, generating 1.236 GWh of electrical energy in 3.475 operating hours. The Obrigheim nuclear power station thus achieved during this period of 145 days in 1990 an operating availability of 100%. Since its commissioning in October 1968, the Obrigheim reactor station has been operating for 158.341 hours, generating 53.361 GWh (gross), and from test operation started in March 1969 up to the end of 1990, all in all 53.249 GWh have been generated in 157.561 operating hours, which means an availability time ratio of 82.3 %, and a capacity factor of 80.1%. The plant was shut down in 1990 for the 21st refuelling operation including inspection and repair work, for a fictitious period of 942 hours. In addition, power operation was stopped by an order of the supervisory authority for another 4.343 hours, so that the plant remained disconnected from the grid between May 26 and December 31, 1990. In the first part of the year 1990, until May 26, the plant had an excellent availability time ratio and thus contributed about 2.5% of the safe, economic and environmentally sound electricity supplies in Baden-Wuerttemberg. (orig./HP) [de

  7. Detection of microbial volatile organic compounds (MVOC) by means of ion mobility spectroscopy (IMS); Detektion leicht fluechtiger organischer Verbindungen mikrobiellen Ursprungs (MVOC) mittels Ionenmobilitaetsspektrometrie (IMS)

    Energy Technology Data Exchange (ETDEWEB)

    Tiebe, Carlo

    2010-07-01

    Traces of microbial volatile organic compounds (MVOCs) can indicate the growth of moulds in the indoor air. The application of ion mobility spectrometry (IMS) is a very promising method for the detection of these MVOCs due to its high sensitivity. A mobile IMS device was tested to use this analytical-chemical method for in situ indoor air diagnostics. The first part of this work describes the test gas generation of 14 MVOCs in the laboratory. The test gases were produced by preparation of permeation procedures. Due to the MVOCs test gases IMS parameters like reduced mobility (K{sub 0}), relative drift time (t{sub rd}), the concentration dependency of MVOCs signals were determined and the limit of detection (LOD) was calculated. The LODs are in the range of 2 to 192 {mu}g m{sup -3} (1 to 51 ppb{sub V}). In the second part of this manuscript seven different mould species were cultivated on nutrient media and their MVOCs emissions were explored. It was found out, that the MVOCs emissions of moulds have a dependency of species and of their cultivation time. These results are confirmed by principal component analysis (PCA). The identification of these MVOCs was performed by test-related GC-MS analysis and approved these results. The MVOCs emissions were explored in the cultivation of mould mixtures on three different building materials. The IMS-results were interpreted chemo metrically by PCA. It was possible to find different emission patterns of cultivated moulds on building materials without an identification of the MVOCs inside the emission chamber. In 27 field trials of different indoor environments (rooms) the IMS was tested to detect MVOCs. In 59 % of the cases a positive correlation is determined between visible mould-infested rooms and the detected MVOCs by IMS. (orig.)

  8. Enhancing end-to-end QoS for multimedia streaming in IMS-based networks

    NARCIS (Netherlands)

    Ozcelebi, T.; Radovanovic, I.; Chaudron, M.R.V.

    2007-01-01

    Convergence of the emerging IP Multimedia Subsystem(IMS) includes unlicensed, nondedicated and nondeterministic hence uncontrollable. computer access, networks for IP multimedia services. It enables provision of resource demanding real-time services and multimedia communication raising new

  9. [Stefan Hartmann. Revaler Handwerker im Spiegel fer Ratsprotokolle von 1722 bis 1755] / Paul Kaegbein

    Index Scriptorium Estoniae

    Kaegbein, Paul

    2007-01-01

    Arvustus: Stefan Hartmann. Revaler Handwerker im Spiegel fer Ratsprotokolle von 1722 bis 1755. In : Ostseeprovinzen, baltische Staaten und das Nationale. Münster : LIT, 2005. lk. 89-112. Kanuti gildi koondunud ametite organisatsioonist ja struktuurist

  10. [Perceptions of Loss, Decline and Doom in the Baltic Sea - Untergangsvorstellungen im Ostseeraum] / David Feest

    Index Scriptorium Estoniae

    Feest, David, 1969-

    2011-01-01

    Arvustus : Perceptions of Loss, Decline and Doom in the Baltic Sea - Untergangsvorstellungen im Ostseeraum. Berlin : Berliner Wissenschafts-Verlag, 2004. (Die Ostseeregione: Nördliche Dimensionen - Europäische Perspektiven. 1)

  11. Federal Workforce: Attrition Rates at Ex-Im Bank and Similar Agencies

    National Research Council Canada - National Science Library

    Hess, James

    1997-01-01

    .... Financing and protection provided by Ex-Im Bank includes (1) loans to foreign buyers of U.S. exports, (2) loan guarantees to commercial lenders providing repayment protection for loans to foreign buyers...

  12. [Umgesiedelt - Vertrieben. Deutschbalten und Polen 1939-1945 im Warthegau] / Karsten Brüggemann

    Index Scriptorium Estoniae

    Brüggemann, Karsten, 1965-

    2012-01-01

    Arvustus: Umgesiedelt - Vertrieben. Deutschbalten und Polen 1939-1945 im Warthegau / hrsg. von Eckhart Neander und Andrzej Sakson. Marburg : Verlag Herder-Institut 2010. (Tagungen zur Ostmitteleuropa-Forschung, 29)

  13. Global R&D through the Intelligent Manufacturing Systems (IMS) program

    Science.gov (United States)

    Huray, Paul G.

    1997-01-01

    The industry-led, international intelligent manufacturing systems (IMS) program provides a special vehicle for joint research and development between government, industry and academia in the United States, Canada, Japan, Australia, and Europe. Since its beginning in 1989, the IMS program has progressed through a feasibility phase which demonstrated that international legal barriers, trade issues, and intellectual property problems could be overcome. The program is constructed to provide higher quality design, customized products, shorter delivery cycles and lower costs. Interactions between partner companies have led to new business opportunities for mutual profit and some claim to have learned strategic information about their international competitors. The IMS program is growing through the participation of hundreds of corporate and university partners who share responsibilities in specific projects and jointly reap benefits for their manufacturing products and processes. The logic for choosing or not choosing the IMS mechanisms will be discussed and R and D projects will be identified.

  14. MALDI (matrix assisted laser desorption ionization) Imaging Mass Spectrometry (IMS) of skin: Aspects of sample preparation.

    Science.gov (United States)

    de Macedo, Cristiana Santos; Anderson, David M; Schey, Kevin L

    2017-11-01

    MALDI (matrix assisted laser desorption ionization) Imaging Mass Spectrometry (IMS) allows molecular analysis of biological materials making possible the identification and localization of molecules in tissues, and has been applied to address many questions on skin pathophysiology, as well as on studies about drug absorption and metabolism. Sample preparation for MALDI IMS is the most important part of the workflow, comprising specimen collection and preservation, tissue embedding, cryosectioning, washing, and matrix application. These steps must be carefully optimized for specific analytes of interest (lipids, proteins, drugs, etc.), representing a challenge for skin analysis. In this review, critical parameters for MALDI IMS sample preparation of skin samples will be described. In addition, specific applications of MALDI IMS of skin samples will be presented including wound healing, neoplasia, and infection. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Seismic Calibration of Group 1 IMS Stations in Eastern Asia for Improved IDC Event Location

    National Research Council Canada - National Science Library

    Murphy, J. R; Rodi, W. L; Johnson, M; Sultanov, J. D; Bennett, T. J; Toksoz, M. N; Ovtchinnikov, V; Barker, B. W; Rosca, A. M; Shchukin, Y

    2006-01-01

    .... In order to establish a robust nuclear test monitoring capability, it is necessary to calibrate the IMS seismic stations used in monitoring, to account for systematic deviations from the nominal travel time curves...

  16. Detection of Atmospheric Explosions at IMS Monitoring Stations using Infrasound Techniques

    National Research Council Canada - National Science Library

    Christie, Douglas R; Kennett, Brian L; Tarlowski, Chris

    2006-01-01

    Work is continuing on the development of infrasound techniques that can be used to improve detection, location and discrimination capability for atmospheric nuclear explosions at International Monitoring System (IMS...

  17. [David Feest. Zwangskollektivierung im Baltikum : die Sowjetisierung des estnischen Dorfes 1944-1953] / Anu Mai Kõll

    Index Scriptorium Estoniae

    Kõll, Anu Mai, 1946-

    2008-01-01

    Arvustus: Feest, David. Zwangskollektivierung im Baltikum : die Sowjetisierung des estnischen Dorfes 1944-1953. Köln [etc.] : Böhlau, 2007. Esimesest rahvusvaheliselt kättesaadavast laiahaardelisest Eesti kollektiviseerimist käsitlevast teosest

  18. Der Einsatz von Online-Datenbanken für Objektinnovationen im Systemgeschäft

    OpenAIRE

    Noch, Rainer

    1990-01-01

    Der Einsatz von Online-Datenbanken für Objektinnovationen im Systemgeschäft. - Augsburg : FGM-Verl., 1990. - 62, LVII S. - Zugl.: Augsburg, Univ., Diplomarb. - (Arbeitspapiere zur Schriftenreihe Schwerpunkt Marketing ; 31)

  19. Physik im 21. Jahrhundert Essays zum Stand der Physik

    CERN Document Server

    Röss, Dieter

    2011-01-01

    Physik ist eine höchst lebendige Wissenschaft! Einmal gewonnene Grundlagen-Erkenntnisse lassen sich auf unübersehbar viele Anwendungsbereiche anwenden. Experimentell gesichertes Detailwissen wächst heute in wenigen Dekaden lawinenartig in eine Größenordnung, die selbst für den Fachmann im Ganzen nicht mehr überschaubar ist. Dieses Werk wählt einen neuen Zugang: Beschränkung auf wenige, exemplarische Teilgebiete der modernen Physik bei Darstellung ihrer Zusammenhänge in aller Tiefe. Verfasser der Beiträge sind herausragende Wissenschaftler mit großer Lebenserfahrung, die dem Leser in ihrem Fachgebiet Zusammenhänge erschließen und Ausblicke in zukünftige Möglichkeiten eröffnen. Mit ihrer in langjähriger Lehrtätigkeit gesammelten Erfahrung formulieren sie das in einem reichen Forscherleben gesammeltes Wissen ohne Abstriche an den Erkenntniswert so, dass es von einer elementaren Basis aus zugänglich ist.

  20. Performance analysis of IMS based LTE and WIMAX integration architectures

    Directory of Open Access Journals (Sweden)

    A. Bagubali

    2016-12-01

    Full Text Available In the current networking field many research works are going on regarding the integration of different wireless technologies, with the aim of providing uninterrupted connectivity to the user anywhere, with high data rates due to increased demand. However, the number of objects like smart devices, industrial machines, smart homes, connected by wireless interface is dramatically increasing due to the evolution of cloud computing and internet of things technology. This Paper begins with the challenges involved in such integrations and then explains the role of different couplings and different architectures. This paper also gives further improvement in the LTE and Wimax integration architectures to provide seamless vertical handover and flexible quality of service for supporting voice, video, multimedia services over IP network and mobility management with the help of IMS networks. Evaluation of various parameters like handover delay, cost of signalling, packet loss,, is done and the performance of the interworking architecture is analysed from the simulation results. Finally, it concludes that the cross layer scenario is better than the non cross layer scenario.

  1. Politische Bildung im Kontext von Regierung, Unterricht und Zucht

    Directory of Open Access Journals (Sweden)

    Thomas Rucker

    2014-02-01

    Full Text Available Johann Friedrich Herbart (1776-1841 gilt als der Begründer der wissenschaftlichen Pädagogik. In diesem Beitrag wird zu zeigen versucht, dass Herbart die Unterstützung politischer Bildung als eine Aufgabe von Regierung, Unterricht und Zucht bestimmt und in seinem Werk wichtige „Bausteine“ für eine Theorie der politischen Bildung unter den Bedingungen von Erziehung vorlegt hat. Nach Herbart ist das politische Selbst- und Weltverhältnis auf Sachverhalte bezogen, die nicht nur die Lebensführung einzelner Menschen, sondern die Lebensführung einer Mehrzahl von Menschen betreffen. Nicht das Zusammenleben von Menschen generell ist jedoch Orientierungsgesichtspunkt des politischen Selbst- und Weltverhältnisses, sondern nur das problematisch gewordene Zusammenleben. Politik ergibt sich nach Herbart aus einem Konflikt hinsichtlich der Frage, wie das Zusammenleben von Menschen geregelt sein sollte. Während die Regierung lediglich mittelbar einen Beitrag zur politischen Bildung leistet, indem sie die Voraussetzungen für Unterricht und Zucht bereitstellt, fungieren die beiden zuletzt genannten Formen von Erziehung als die eigentlichen Medien, in denen die politische Bildung im Sinne Herbarts ihren Ort hat.

  2. Primary fibrosarcoma im small intestine of dog - Case report

    Directory of Open Access Journals (Sweden)

    Geórgia Modé Magalhães

    2015-06-01

    Full Text Available ABSTRACT. Magalhães G.M., Santilli J., Calazans S.G., Nishimura L.T., Cerejo S.A. & Dias F.G.G. [Primary fibrosarcoma im small intestine of dog - Case report.] Fibrossarcoma primário em intestino delgado de cão - Relato de caso. Revista Brasileira de Medicina Veterinária, 37(2:145-148, 2015. Programa de Pós-Graduação em Medicina Veterinária de Pequenos Animais, Universidade de Franca, Av. Dr. Armando Salles Oliveira, 201, Cx postal 82, Parque Universitá- rio, Franca, SP 14404-600, Brasil. E-mail: georgiamode@hotmail.com Intestinal neoplasms are uncommon in dogs, and among the most frequently diagnosed are smooth muscle, lymphomas and carcinomas. The fibrosarcoma is extremely rare in the intestine of animals of this species therefore, little is known about the macroscopic and behavior of this tumor. Given this unusual intestinal disease in dogs, the present study aimed to report a case of intestinal fibrosarcoma in a poodle breed dog, 15 years old, with no apparent clinical signs. The mass was pedunculated, whitish and firm consistency. The diagnosis was made by histopathology. After four months of surgical excision, there was no recurrence and metastasis. We conclude that the intestinal fibrosarcoma has low aggressiveness, are rare and can present macroscopic pediculated.

  3. Cyber-Mobbing als verletzender Sprechakt im Sinne Judith Butlers

    Directory of Open Access Journals (Sweden)

    Katharina Luckner

    2012-12-01

    Full Text Available Dieser Beitrag widmet sich der Frage, inwiefern Cyber-Mobbing unter Bezugnahme auf Judith Butlers sprach- bzw. diskurstheoretisches Konzept als verletzender Sprechakt verstanden werden kann. Zu diesem Zweck werden in einem ersten Schritt die Besonderheiten von Cyber-Mobbing aufgezeigt und im Anschluss daran ein für diesen Text geeigneter Cyber-Mobbing-Begriff formuliert. Daraufhin erfolgt eine interpretative Auseinandersetzung mit der Butlerschen Konzeption verletzender Sprechakte, bevor anschließend anhand wesentlicher Schnittstellen herausgearbeitet wird, inwiefern Cyber-Mobbing als ein solcher verletzender sprachlicher Akt begriffen werden kann. Resümierend werden die zentralen Ergebnisse der Ausarbeitung zusammengefasst und es wird danach gefragt, welche Konsequenzen bzw. Folgen sich hieraus für ein mögliches verändertes Verständnis von Cyber-Mobbing ergeben.This Paper argues whether cyber bullying can be understood as violating speach act with reference to Judith Butler by starting with a definition of cyber bullying (respectively the term cyber 'mobbing' which is used synonymously in German speaking countries and an outline of Butler's theory. After that, the question of a new or different understanding of cyber bullying and its consequences is discussed.

  4. Habitusformen von Eltern im Kontext der Computerspielnutzung ihrer Kinder

    Directory of Open Access Journals (Sweden)

    Henrike Friedrichs

    2014-09-01

    Full Text Available Dieser Artikel stellt die Sichtweisen von Eltern auf das Computerspielverhalten ihrer Kinder und ihr erzieherisches Handeln bezüglich des Computerspielens vor. Die Ergebnisse stammen aus einem Forschungsprojekt der Fakultät für Erziehungswissenschaft der Universität Bielefeld mit dem Titel "Computerspielnutzung aus Elternsicht". Die empirische Studie aus dem Jahr 2014 umfasst 28 leitfadengestützte Interviews mit Elternpaaren. Die Ergebnisse zeigen u. a., dass der mediale Habitus (Kommer/Biermann 2012 die Ausgestaltung des medienerzieherischen Habitus (Friedrichs 2013 beeinflusst; d. h. bspw., dass computerspielerfahrene Eltern ein differenzierteres Medienerziehungsverhalten im Hinblick auf Computerspiele zeigen, als Eltern, die keine eigenen Computerspielerfahrungen gemacht haben. This article shows parental points of view on computer game habits of children and the educational acting of parents concerning computer games. The results are product of the research project "Parental views on children and adolescents playing computer games" of the Faculty of Educational Science of Bielefeld University. The empirical study from 2014 includes 28 qualitative interviews with both parents. The results show among other things that the media-related habitus of parents influences their media-educational habitus. This means e. g. that parents experienced on video games show a more differentiated educational behaviour concerning video games than parents without such kind of experience.

  5. Separation of toluene from n-heptane by liquid–liquid extraction using binary mixtures of [bpy][BF4] and [4bmpy][Tf2N] ionic liquids as solvent

    International Nuclear Information System (INIS)

    García, Silvia; Larriba, Marcos; García, Julián; Torrecilla, José S.; Rodríguez, Francisco

    2012-01-01

    Highlights: ► Binary mixtures of ionic liquids as extraction solvents of aromatics. ► [4bmpy][Tf 2 N] shows higher capacity but lower selectivity than sulfolane. ► [bpy][BF 4 ] shows lower capacity but higher selectivity than sulfolane. ► Mixed {[4bmpy][Tf 2 N] + [bpy][BF 4 ]} improves both extractive properties. - Abstract: The use of binary mixture of ionic liquids N-butylpyridinium tetrafluoroborate ([bpy][BF 4 ]), and 1-butyl-4-methylpyridinium bis(trifluoromethylsulfonyl)imide ([4bmpy][Tf 2 N]) in the liquid–liquid extraction of toluene from n-heptane has been investigated at 313.2 K and atmospheric pressure. The experimental capacity of extraction and selectivity for this binary mixture has proved to be intermediate to those corresponding to the pure ionic liquids, and they can be predicted using a logarithmic–linear model of solubility. Furthermore, the results showed that the use of binary mixture of {[bpy][BF 4 ] + [4bmpy][Tf 2 N]} at a mole solvent composition around 0.7 for [bpy][BF 4 ] improves both the capacity of extraction of toluene and the selectivity with respect to those of sulfolane, the organic solvent taken as a benchmark. Thus, this mixed ionic liquid could be likely to be used in the extraction of aromatic from aliphatic in replacement to sulfolane.

  6. Messung der Konzentration von D-Dimeren zur Ermittlung physiologischer Referenzbereiche im Verlauf der Schwangerschaft

    OpenAIRE

    Pingel, Nadine

    2011-01-01

    Einleitung: D-Dimere (DDIM) sind Fibrinspaltprodukte. Erhöhte Konzentrationen im Blutplasma sind Ausdruck einer verstärkten Aktivierung des Gerinnungs- und Fibrinolysesystems wie bei venösen Thromboembolien. Ebenfalls einen Zustand erhöhter Hyperkoagulabilität stellt die Schwangerschaft dar. Im Rahmen physiologischer Veränderungen steigen die DDIM in dieser Zeit kontinuierlich an. Referenzbereiche hinsichtlich der DDIM-Konzentration beruhen weitestgehend auf Messungen bei nicht-schwangere...

  7. "In allen guten Buchhandlungen ist zu haben". Buchwerbung in Deutschland im 17. und 18. Jahrhundert

    OpenAIRE

    Hauke, Marie-Kristin

    2005-01-01

    Der Buchhandel entwickelte im Laufe des 17. und 18. Jahrhunderts zahlreiche Hilfsmittel zur Absatzförderung, auf die er als Produzent des „Massenartikels“ Buch angewiesen war und die ihn zum Vorreiter der modernen Wirtschaftswerbung machten. Ausgangsbasis dafür waren die im 16. Jahrhundert entstandenen Werbemittel Buchtitel, Titelblatt und Katalog, die durch die Buchanzeigen in verschiedenen Werbeträgern (Zeitung, Zeitschrift, Intelligenzblatt, Buch) sowie einige kleinere Formen (Handzettel, ...

  8. Innovative Techniken und Algorithmen im Bereich Computational-Finance und Risikomanagement

    OpenAIRE

    Liang, Qian

    2012-01-01

    Diese Dissertation besteht aus zwei aktuellen Themen im Bereich Finanzmathematik, die voneinander unabhängig sind. Beim ersten Thema, "Flexible Algorithmen zur Bewertung komplexer Optionen mit mehreren Eigenschaften mittels der funktionalen Programmiersprache Haskell", handelt es sich um ein interdisziplinäres Projekt, in dem eine wissenschaftliche Brücke zwischen der Optionsbewertung und der funktionalen Programmierung geschlagen wurde. Im diesem Projekt wurde eine funktionale Biblio...

  9. Light-weight internet protocol multimedia subsystem (IMS) client: development for smart mobile devices

    CSIR Research Space (South Africa)

    Masonta, M

    2010-11-01

    Full Text Available : IP multimedia Services Identity Module J2ME: Java 2 Micro-Edition JCP: Java Community Process JSR: Java Specification Request MAGNET: My personal Adaptive Global Network MGCF: Media Gateway Control Function MIDP: Mobile Information Device...) .................................................................. 30 Figure 2.15: IMS-Communicator Screenshot (PT Inova??o, 2007) .......................................... 31 Figure 2.16: UCT IMS Client Screenshot (Waiting & Good, 2007) ......................................... 32 Figure 3.1: Sun Java WTK 2...

  10. Multimedia als Entwicklungsfaktor im ländlichen Raum? : Fallbeispiel Wirtschaftsregion Friedrichshafen/Bodensee

    OpenAIRE

    Haupenthal, Edmund; Leuninger, Stefan; Beermann, Petra; Kutter, Martina

    1998-01-01

    Im Rahmen der vorliegenden empirischen Studie in der Wirtschaftsregion Friedrichshafen wurden die Wechselwirkungen zwischen regionalen Strukturfaktoren und „Multimedia-Entwicklungen“ im ländlichen Raum untersucht. Die positive Multimedia-Entwicklung geht auf folgende regionale Erfolgsfaktoren zurück: die politische Akzeptanz der neuen Technologie, die Vorhaltung der Multimedia-Akademie, die regionale Nachfrage, die Verfügbarkeit ausreichenden Know-hows und Humankapitals sowie das Vorhandensei...

  11. Antisemitismus, Shoah und deutsche Verantwortung:(Nach)Wirkungen des Nationalsozialismus im medialen Nahostdiskurs

    OpenAIRE

    Ullrich, Peter

    2010-01-01

    Wahrscheinlich wird kein anderer internationaler Konflikt derart kontrovers und emotional in der bundesrepublikanischen Öffentlichkeit sowie auch und gerade in der politischen Linken diskutiert wie der israelisch-palästinensische oder weiter gefasst, der Nahost-Konflikt. Aus diesem Grund nimmt dieses Thema einen besonderen Platz in der Bildungsarbeit der Rosa-Luxemburg- Stiftung im Inland wie im Ausland ein. Wenngleich dabei auch in der Stiftung und ihrem Umfeld die Meinungen auseinandergehen...

  12. Produkteinführung im Umfeld des Niedergangs: Die Blu-ray Disk

    OpenAIRE

    Oestreicher, Klaus; Walton, Nigel; Newnham, M.

    2014-01-01

    Dieses Kapitel diskutiert die Problematik existenzieller Bedrohung durch radikale Innovationen. Virtuelle Marktangebote verändern Märkte im Home Entertainment und das Konsumverhalten grund¬legend. Zunehmend gefährden dematerialisierte Produkte, welche zu Services werden und Folge der Information Communication Tech¬nologies (ICT) sind, die Lebensfähigkeit physischer Produkte. Deren Märkte sind im Niedergang und das bedroht nicht nur die Hersteller optischer Disks (CD und DVD), sondern beeinflu...

  13. Original models of NGN/IMS-networks surrounded by circuit-switched systems

    OpenAIRE

    Kulikov, Nikolay

    2014-01-01

    On obtaining of the Alexander Graham Bell a patent for invention of the telephone in 1987, the communication system consistently has gone through several evolutionary stages: from analog lines and manual switches to video telephony and IMS architecture. Each of the stages can be described by specific switching systems, data transmission systems and types of transmitted information. After implementation of such solution, it is possible to create a number of access nodes in the Operators IMS-ne...

  14. Method for Estimating Evaporative Potential (IM/CLO) from ASTM Standard Single Wind Velocity Measures

    Science.gov (United States)

    2016-08-10

    IM/CLO) FROM ASTM STANDARD SINGLE WIND VELOCITY MEASURES DISCLAIMER The opinions or assertions contained herein are the private views of the...USARIEM TECHNICAL REPORT T16-14 METHOD FOR ESTIMATING EVAPORATIVE POTENTIAL (IM/CLO) FROM ASTM STANDARD SINGLE WIND VELOCITY... ASTM STANDARD SINGLE WIND VELOCITY MEASURES Adam W. Potter Biophysics and Biomedical Modeling Division U.S. Army Research Institute of Environmental

  15. Pragmatic awareness of Suggestions: From (Im)Polite Mannerism to Attitudinal Appropriateness

    OpenAIRE

    Hamid Allami; Nasim Boustani

    2017-01-01

    The present research seeks to determine: (a) Iranian EFL learners’ application of suggestion semantic formulae ;(b) their attitude of appropriateness in terms of confidence in the employment of appropriate supportive moves; (c), their (im)polite mannerism with respect to the selected strategies; and (d) the relationship between attitude of appropriateness and mannerism of (im)politeness. An Oxford Quick placement Test (OQPT) was administered among 60 Iranian EFL learners to check their langua...

  16. Die nonverbale Kommunikation im Bundestagswahlkampf 2002:Gerhard Schröder versus Edmund Stoiber

    OpenAIRE

    Dieball, W. (Werner)

    2004-01-01

    Diese interdisziplinäre Dissertation aus dem Fachbereich Politikwissenschaften verfolgt vordergründig das Ziel, die Wirkungsweise der nonverbalen Kommunikation im Bundestagswahlkampf 2002 zu analysieren. Im Zentrum der empirisch-analytischen Untersuchung stehen Gerhard Schröder und Edmund Stoiber, die nach den nonverbalen Merkmalen: äußeres Erscheinungsbild, Mimik, Stimmklang, Gestik und Motorik untersucht werden. Das leitende Forschungsinteresse der Arbeit besteht darin, zu eruieren, inwiewe...

  17. Datengeleitetes Lernen im studienbegleitenden Deutschunterricht am Beispiel des KoGloss-Ansatzes

    OpenAIRE

    Dubova, Agnese; Proveja, Egita

    2016-01-01

    Der vorliegende Aufsatz stellt den sprachdidaktischen Ansatz KoGloss vor und beschreibt die Möglichkeiten seines Einsatzes im studienbegleitenden Deutschunterricht. Als eine der Formen des datengeleiteten Lernens ermöglicht der KoGloss-Ansatz eine forschungsorientierte und lernerzentrierte Herangehensweise, die insbesondere im akademischen Sprachunterricht gefragt ist. Eine korpusbasierte Erschließung von (Fach-)Wörtern und komplexen sprachlichen Mustern, das learning by doing, die Kooperatio...

  18. Robust stator resistance identification of an IM drive using model reference adaptive system

    International Nuclear Information System (INIS)

    Madadi Kojabadi, Hossein; Abarzadeh, Mostafa; Aghaei Farouji, Said

    2013-01-01

    Highlights: ► We estimate the stator resistance and rotor speed of the IM. ► We proposed a new quantity to estimate the speed and stator resistance of IM. ► The proposed algorithm is robust to rotor resistance variations. ► We estimate the IM speed and stator resistance simultaneously to avoid speed error. - Abstract: Model reference adaptive system (MRAS) based robust stator resistance estimator for sensorless induction motor (IM) drive is proposed. The MRAS is formed with a semi-active power quantity. The proposed identification method can be achieved with on-line tuning of the stator resistance with robustness against rotor resistance variations. Stable and efficient estimation of IM speed at low region will be guaranteed by simultaneous identification of IM speed and stator resistance. The stability of proposed stator resistance estimator is checked through Popov’s hyperstability theorem. Simulation and experimental results are given to highlight the feasibility, the simplicity, and the robustness of the proposed method.

  19. Respuestas faciales ante imágenes de advertencia de tabaco

    Directory of Open Access Journals (Sweden)

    M. A. Muñoz

    Full Text Available Resumen En 2003, la Comisión Europea propuso una serie de advertencias visuales para ser incluidas en los embalajes de tabaco, con el objetivo de motivar a los fumadores a dejar de fumar y promover actitudes negativas hacia el tabaco. El objetivo de este estudio fue evaluar el impacto de las advertencias sanitarias mediante autoinformes y medidas psicofisiológicas. Cincuenta sujetos sanos (19-23 años visionaron un conjunto de treinta y seis imágenes de diferente contenido emocional y veinticuatro del banco de imágenes preventivas propuestas por la Comisión Europea. Se registró la actividad eléctrica de los músculos cigomático mayor y corrugador mientras los sujetos visionaban estas imágenes. A continuación, los participantes evaluaban las imágenes en las dimensiones de agradabilidad y activación. Los resultados muestran una mayor actividad eléctrica del musculo corrugador ante la presentación de imágenes desagradables comparadas con advertencias desagradables incluidas en los paquetes de tabaco. Estos resultados sugieren que la campaña preventiva podría beneficiarse de imágenes preventivas más impactantes, promoviendo así la activación del sistema motivacional evitativo/defensivo.

  20. A critical analysis of Sorrell v. IMS Health, Inc.: Pandora's box at best.

    Science.gov (United States)

    Bibet-Kalinyak, Isabelle

    2012-01-01

    Sorrell v. IMS Health, Inc. ("IMS Health"), a remarkable health care case with resounding First Amendment and economic repercussions, features the clashing interests of the State of Vermont and aggressive free market players from the pharmaceutical and data mining industries in a constitutional battle over Free Speech. In 2007, Vermont enacted Act 80, The Confidentiality of Prescription Information Act, prohibiting the sale, disclosure, and use of pharmacy records. Together with two other data miners and PhRMA, an association of brand-name drug manufacturers, IMS Health successfully challenged the constitutionality of Act 80 on First Amendment grounds. This article examines the legal arguments of IMS Health and Act 80 and analyzes why IMS Health stands out for potentially challenging the traditional doctrine of commercial speech and the resulting legal implications. After reviewing the Supreme Court's reasoning, the article concludes that, although the Supreme Court reached the appropriate outcome, it did so by unjustifiably departing from the established legal doctrine of commercial speech and the American tradition of consumer protection. At best, IMS Health's reasoning opens a legal Pandora's Box potentially leading to an onset of new commercial speech challenges; at worst, it manufactured a Trojan Horse aimed at eroding the traditional regulatory safeguards that maintain a balance between the needs of consumers and corporations alike.

  1. Spontane Mobilisierung und der Wandel kollektiver Formationen im Internet. Eine Fallstudie zur PEGIDA-Bewegung

    Directory of Open Access Journals (Sweden)

    Sang-hui Nam

    2016-11-01

    Full Text Available Der vorliegende Beitrag beschäftigt sich mit der Frage, wie sich eine aus spontaner Mobilisierung entstandene soziale Bewegung als kollektive Formation im Internet entwickelt. Da spontane Bewegungen in aller Regel nur über eine schwache kollektive Identität verfügen, werden sie bislang überwiegend als Übergangsphänomen betrachtet. Viele Studien beschäftigten sich eher mit den Folgen spontaner Mobilisierung, insbesondere der Frage, wie daraus eine nachhaltige Bewegung entstehen kann. Die kollektive Formation selbst ist bis dato weitgehend eine Blackbox geblieben. In der vorliegenden Studie widme ich mich folgenden zentralen Forschungsfragen: 1. Wie werden kollektive Formationen aus spontanen ProtestteilnehmerInnen dargestellt und generiert? 2. Wie ändern sich diese im Verlauf der Mobilisierung? Im Mittelpunkt der empirischen Analyse stehen Online-Kommentare, die eine zunehmend wichtige Rolle für soziale Bewegungen und spontane Mobilisierungsprozesse spielen. Am Beispiel von PEGIDA wird die Konstruktion einer kollektiven Formation über Live-Kommentare zu Live-Übertragungen von PEGIDA-Demonstrationen sowie deren Wandel in drei Phasen untersucht. Im ersten Schritt werden die soziotechnischen Grundlagen kollektiven Handelns im Internet erläutert. Der zweite Schritt befasst sich mit der methodischen Vorgehensweise. Im dritten Schritt werden ausgewählte Textpassagen von Online-Kommentaren analysiert. Anschließend wird der Wandel kollektiver Formationen nachgezeichnet. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs170138

  2. Medida Interpessoal de Psicopatia (IM-P: estudo preliminar no contexto brasileiro Interpersonal Measure of Psychopathy (IM-P: preliminary study in the Brazilian context

    Directory of Open Access Journals (Sweden)

    Tárcia Rita Davoglio

    2011-01-01

    Full Text Available INTRODUÇÃO: A observação direta do comportamento interpessoal é um recurso importante na descrição e diagnóstico da personalidade psicopática. A Medida Interpessoal de Psicopatia (Interpersonal Measure of Psychopathy, IM-P é um instrumento psicométrico composto por 21 itens, desenvolvido para ser utilizado em associação com outras escalas de avaliação da psicopatia. Foca-se, especificamente, nos comportamentos interpessoais e aspectos não verbais evidentes na interação do entrevistador com indivíduos que apresentam características psicopáticas. OBJETIVO: Descrever resultados preliminares sobre a investigação de aspectos interpessoais da psicopatia mediante a utilização da IM-P, incluindo as etapas de tradução/adaptação e avaliação de confiabilidade interavaliadores da IM-P, em uma amostra de adolescentes brasileiros. MÉTODO: Trata-se de estudo transversal, descritivo e correlacional realizado com 20 adolescentes masculinos cumprindo medida socioeducativa com privação de liberdade na Região Metropolitana de Porto Alegre (RS. Após os procedimentos de tradução da escala, treinamento dos pesquisadores e teste piloto por meio de uma entrevista semiestruturada, a IM-P foi pontuada por três juízes independentes. RESULTADOS: Os resultados estatísticos, obtidos através do coeficiente de concordância de Kendall, revelaram grau de concordância interavaliadores elevado e satisfatório para os escores totais da IM-P (W = 0,84; p INTRODUCTION: The direct observation of interpersonal behaviors is an important resource in the description and diagnosis of the psychopathic personality. The Interpersonal Measure of Psychopathy (IM-P is a psychometric instrument comprised of 21 items, designed to be applied in association with other instruments that also evaluate psychopaths. It focuses specifically on interpersonal and non-verbal behaviors that become evident during the interaction between the interviewer and individuals

  3. Results from an Interval Management (IM) Flight Test and Its Potential Benefit to Air Traffic Management Operations

    Science.gov (United States)

    Baxley, Brian; Swieringa, Kurt; Berckefeldt, Rick; Boyle, Dan

    2017-01-01

    NASA's first Air Traffic Management Technology Demonstration (ATD-1) subproject successfully completed a 19-day flight test of an Interval Management (IM) avionics prototype. The prototype was built based on IM standards, integrated into two test aircraft, and then flown in real-world conditions to determine if the goals of improving aircraft efficiency and airport throughput during high-density arrival operations could be met. The ATD-1 concept of operation integrates advanced arrival scheduling, controller decision support tools, and the IM avionics to enable multiple time-based arrival streams into a high-density terminal airspace. IM contributes by calculating airspeeds that enable an aircraft to achieve a spacing interval behind the preceding aircraft. The IM avionics uses its data (route of flight, position, etc.) and Automatic Dependent Surveillance-Broadcast (ADS-B) state data from the Target aircraft to calculate this airspeed. The flight test demonstrated that the IM avionics prototype met the spacing accuracy design goal for three of the four IM operation types tested. The primary issue requiring attention for future IM work is the high rate of IM speed commands and speed reversals. In total, during this flight test, the IM avionics prototype showed significant promise in contributing to the goals of improving aircraft efficiency and airport throughput.

  4. Freie Lerninhalte im Internet mit Studierenden recherchieren, kommentieren und kompilieren. Zur Gestaltung der online-Selbstlernangebote im hr-Funkkolleg Philosophie

    Directory of Open Access Journals (Sweden)

    Jakob Krebs

    2017-03-01

    Full Text Available Wie lassen sich online frei verfügbare Bildungsinhalte mit Studierenden so zusammenstellen, dass sie als thematisch sortierte Selbstlernmaterialien unkompliziert gefunden werden können – sei es von anderen Studierenden, interessierten Laien oder auch von Lehrkräften in Bildungsinstitutionen? Der vorliegende Werkstattbericht rekonstruiert ein Lernszenario, in dem Studierende vorhandene Materialien im Internet recherchierten, kommentierten und kompilierten, um ein Online-Zusatzangebot zu den Radiosendungen im hr-Funkkolleg Philosophie 2014/15 zu erstellen. Die Rahmenbedingungen dieser ungewöhnlichen universitären Kooperation mit dem Rundfunk werden im ersten Abschnitt vorgestellt. Der zweite Abschnitt skizziert das didaktische Design zusammen mit dem Projektstrukturplan eines produktorientierten kollaborativen Lernsettings mit Wiki-Einsatz. Im dritten Abschnitt werden der Lernerfolg bei den Studierenden sowie einige Herausforderungen benannt, die u. a. in der Abschlussevaluierung zur Sprache kamen. Der vierte Abschnitt macht die Projekterfahrungen für reguläre Lehr- und Lern-Szenarien fruchtbar, in denen nicht nur Studierende mit didaktischen Interessen durch die gemeinsame Gestaltung von Internetangeboten fachlich und methodisch profitieren können. Mit dem Bericht wird somit u. a. veranschaulicht, wie sich Ansätze von Blended, Peer-Assisted und Service Learning produktiv kombinieren lassen.

  5. Was bedeutet Trägheit? Begriff und Wirkung der Trägheit im Rahmen des Wechselverhaltens von Konsumenten im Strommarkt

    NARCIS (Netherlands)

    Henseler, Jörg

    2006-01-01

    In Wissenschaft und Praxis wird die Trägheit der Konsumenten als Ursache der geringen Wechselrate im deutschen Strommarkt für Haushaltskunden diskutiert. Der vorliegende Beitrag arbeitet heraus, dass es sich bei dieser Argumentation entweder um eine Tautologie oder ein Synomym für den Verbleib in

  6. CASL VMA FY16 Milestone Report (L3:VMA.VUQ.P13.07) Westinghouse Mixing with COBRA-TF

    Energy Technology Data Exchange (ETDEWEB)

    Gordon, Natalie [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-09-30

    COBRA-TF (CTF) is a low-resolution code currently maintained as CASL's subchannel analysis tool. CTF operates as a two-phase, compressible code over a mesh comprised of subchannels and axial discretized nodes. In part because CTF is a low-resolution code, simulation run time is not computationally expensive, only on the order of minutes. Hi-resolution codes such as STAR-CCM+ can be used to train lower-fidelity codes such as CTF. Unlike STAR-CCM+, CTF has no turbulence model, only a two-phase turbulent mixing coefficient, β. β can be set to a constant value or calculated in terms of Reynolds number using an empirical correlation. Results from STAR-CCM+ can be used to inform the appropriate value of β. Once β is calibrated, CTF runs can be an inexpensive alternative to costly STAR-CCM+ runs for scoping analyses. Based on the results of CTF runs, STAR-CCM+ can be run for specific parameters of interest. CASL areas of application are CIPS for single phase analysis and DNB-CTF for two-phase analysis.

  7. Induced apoptosis by mild hyperthermia occurs via telomerase inhibition on the three human myeloid leukemia cell lines: TF-1, K562, and HL-60.

    Science.gov (United States)

    Deezagi, Abdolkhaleg; Manteghi, Sanaz; Khosravani, Pardis; Vaseli-Hagh, Neda; Soheili, Zahra-Soheila

    2009-09-01

    The purpose of this research was to understand the effect of hyperthermia on the telomerase activity in human leukemic cell lines (HL-60, K562, and TF-1). The cells were treated by hyperthermia at the range of 41-44 degrees C for 120 min and incubated for 96 h. Then telomerase activity, cell proliferation, and apoptosis were assessed. The results indicated that hyperthermia significantly induced apoptosis on the cells. The cells exhibited pre-apoptotic pattern at 41 and 42 degrees C at 60-120 min and apoptotic pattern at 43 and 44 degrees C over 30 min after hyperthermia. Telomerase activity (that was assayed immediately after hyperthermia) was stable at 41-42 degrees C for 60 min but decreased to 35-40% at 120 min. However, at severe hyperthermia (43-44 degrees C) telomerase activity was decreased in a time- and dose-dependent manner. Following hyperthermia (41-44 degrees C up to 120 min), the cells were incubated for 96 h. In these conditions, the telomerase activity was decreased by about 60-80% in comparison with that untreated control cells.

  8. Effect of Twist Pitch in the Strands on the Saturation and Losses in the Nb3Sn Strands for the ITER TF CICC

    International Nuclear Information System (INIS)

    Martovetsky, N.N.

    2007-01-01

    ITER TF coils will see a significant longitudinal magnetic field in the event of the plasma disruption. This abrupt change of magnetic fields results in the appearance of an additional electrical field in the strands. The mechanism of this electrical field is the induced currents that expel the flux from the strands. This effect was known since the late 1970's [1-3] and most of the details necessary for the analyses given in this report are presented in [4]. Let's assume for simplicity a zero transport current in the strand. When a longitudinal pulsed field is applied, the outer filaments will carry an induced current repelling the change of flux. The current density of this current is 'critical' in the simplification of Bean's critical state model, where superconducting transition is represented as j=j c at any non-zero electrical field and zero where the electrical field has not penetrated. In reality, since the current density is roughly logarithmic with the electrical field, E=E c *exp[(j-j c )/jo], Bean's model is just a simplification, and current density is slightly nonuniform in the outer filament and more so for the interior strands. The inner portion of the filaments will carry a current of the opposite sign. Even in the Bean's model it is not uniform, but the assumption that it is uniform and less than critical simplifies mathematics significantly and does not deviate far from the real current density distribution. In certain circumstances, the average electrical field in the strands will be high enough to exceed the take-off electrical field averaged across the cross section. In this case, the multifilamentary strand will become unstable and will experience transition to the normal state. With zero transport current, it will eventually recover, of course. This phenomenon is analogous to the flux jump. If the strand carries a transport current, the situation becomes more complicated. If it goes unstable and the transport current is higher than the

  9. Der Tatort im studienbegleitenden Deutschunterricht ab B2. Potenziale für heterogene Studierendengruppen im nichtdeutschsprachigen Raum

    Directory of Open Access Journals (Sweden)

    Michael Seyfarth

    2016-04-01

    Full Text Available Aktuelle Diskussionen zum studienbegleitenden Deutschunterricht verdeutlichen die Notwendigkeit danach, sich bei curricularen Überlegungen sowohl an institutionellen Rahmenbedingungen als auch an spezifischen Bedürfnissen der Studierenden zu orientieren. Da Lehrwerke den damit einhergehenden Anforderungen nach Offenheit und Adaptierbarkeit nicht gerecht werden können, sind mittelfristig alternative Konzepte gefragt, die es ermöglichen, im Zuge curricularer Überlegungen die notwendige Kohärenz zwischen einzelnen Unterrichtseinheiten herzustellen und dennoch eine flexible Anpassung an konkrete Lernkontexte zu erlauben. Der vorliegende Beitrag stellt ein solches Konzept vor. Ausgehend von der Arbeit am Tatort werden drei Lernbereiche vorgestellt, die neben der Arbeit am Film auch die Arbeit an angrenzenden Themen und Texten sowie darauf aufbauend die Entwicklung studienbegleitender kommunikativer Handlungskompetenz vorsehen.  Current discussions on teaching German alongside the core subjects at university show the necessity to consider both institutional requirements and the students' individual goals when establishing teaching objectives. Existing text books, however, suffer from an overly tight structure that doesn’t allow the instructor to use additional material in order to focus on the specific needs of the students in a suitable way. Flexible concepts are needed which serve as a framework and which can be realized with texts and tasks focusing on what is required by a specific learning context. This paper presents such an approach, using the German feature film Tatort. Besides ideas for working with the audiovisual material we will present opportunities that come along with the various texts and discussions in media and social networks arising around the film as well as ways for combining these aspects with developing language skills for the academic context.

  10. CD31-Expression am Primärtumor und Nachweis hämatogen disseminierter Tumorzellen im Knochenmark von Brustkrebspatientinnen

    OpenAIRE

    Eisenmann, Petra

    2005-01-01

    Der Nachweis von disseminierten Tumorzellen im Knochenmark von Patientinnen mit primärem Mammakarzinom ist ein wichtiger prognostischer Parameter. In der vorliegenden Arbeit wurde der Nachweis von CD31 am Primärtumor Mammakarzinom mit dem Auftreten von Mikrometastasen im Knochenmark korreliert. Ferner wurde die prognostische Bedeutung von disseminierten Tumorzellen im Knochenmark und die prognostische Bedeutung von CD31 evaluiert. Bei 50 Patientinnen des Gesamtkollektivs von 195 (25,6%) wu...

  11. Associations between United States Medical Licensing Examination (USMLE) and Internal Medicine In-Training Examination (IM-ITE) scores.

    Science.gov (United States)

    McDonald, Furman S; Zeger, Scott L; Kolars, Joseph C

    2008-07-01

    Little is known about the associations of previous standardized examination scores with scores on subsequent standardized examinations used to assess medical knowledge in internal medicine residencies. To examine associations of previous standardized test scores on subsequent standardized test scores. Retrospective cohort study. One hundred ninety-five internal medicine residents. Bivariate associations of United States Medical Licensing Examination (USMLE) Steps and Internal Medicine In-Training Examination (IM-ITE) scores were determined. Random effects analysis adjusting for repeated administrations of the IM-ITE and other variables known or hypothesized to affect IM-ITE score allowed for discrimination of associations of individual USMLE Step scores on IM-ITE scores. In bivariate associations, USMLE scores explained 17% to 27% of the variance in IME-ITE scores, and previous IM-ITE scores explained 66% of the variance in subsequent IM-ITE scores. Regression coefficients (95% CI) for adjusted associations of each USMLE Step with IM-ITE scores were USMLE-1 0.19 (0.12, 0.27), USMLE-2 0.23 (0.17, 0.30), and USMLE-3 0.19 (0.09, 0.29). No single USMLE Step is more strongly associated with IM-ITE scores than the others. Because previous IM-ITE scores are strongly associated with subsequent IM-ITE scores, appropriate modeling, such as random effects methods, should be used to account for previous IM-ITE administrations in studies for which IM-ITE score is an outcome.

  12. Spannungsaktivierte Natriumkanäle im Corpus luteum des Primaten und ihre Rolle bei der Regulation von Steroidproduktion und Luteolyse

    OpenAIRE

    Bulling, Andreas

    2008-01-01

    Im Ovar des Menschen und im Corpus Luteum des Rhesusaffen konnte die mRNA für einen bislang nur im peripheren Nervensystem und in neuroendokrinen Zellen gefundenen spannungsaktivierten Natriumkanal (eNaK, SCN9A) nachgewiesen werden. In kultivierten humanen Granulosaluteinzellen wurden sowohl die Transkriptmenge, als auch die durch depolarisierende Spannungspulse ausgelösten, TTX-sensitiven transienten Ströme durch hCG negativ reguliert. Trotz des gleichzeitigen Vorkommens spannungsaktivierter...

  13. INSTANT MESSENGER (IM) APPLICATION USAGE AT WORKPLACE AND WORKING CULTURE OF A PUBLIC UNIVERSITY SUPPORTING STAFF IN KOTA KINABALU SABAH.

    OpenAIRE

    Nading, Dorina; Morshidi, Azizan

    2016-01-01

    Instant Messenger (IM) has becoming a new form of social relations tool in which people interact, dialogue, collaborate and exchange information. Many organizations and companies have adapted their management strategies with the utilization of IM applications, both internally or externally. The popularity of IM in local organizational management in such a way that government agencies, companies, universities, colleges and schools. The use of applications such as wechat, whatsApp messenger...

  14. Improved detection of Mycobacterium bovis infection in bovine lymph node tissue using immunomagnetic separation (IMS-based methods.

    Directory of Open Access Journals (Sweden)

    Linda D Stewart

    Full Text Available Immunomagnetic separation (IMS can selectively isolate and concentrate Mycobacterium bovis cells from lymph node tissue to facilitate subsequent detection by PCR (IMS-PCR or culture (IMS-MGIT. This study describes application of these novel IMS-based methods to test for M. bovis in a survey of 280 bovine lymph nodes (206 visibly lesioned (VL, 74 non-visibly lesioned (NVL collected at slaughter as part of the Northern Ireland bovine TB eradication programme. Their performance was evaluated relative to culture. Overall, 174 (62.1% lymph node samples tested positive by culture, 162 (57.8% by IMS-PCR (targeting IS6110, and 191 (68.2% by IMS-MGIT culture. Twelve (6.9% of the 174 culture positive lymph node samples were not detected by either of the IMS-based methods. However, an additional 79 M. bovis positive lymph node samples (27 (13.1% VL and 52 (70.3% NVL were detected by the IMS-based methods and not by culture. When low numbers of viable M. bovis are present in lymph nodes (e.g. in NVLs of skin test reactor cattle decontamination prior to culture may adversely affect viability, leading to false negative culture results. In contrast, IMS specifically captures whole M. bovis cells (live, dead or potentially dormant which are not subject to any deleterious treatment before detection by PCR or MGIT culture. During this study only 2.7% of NVL lymph nodes tested culture positive, whereas 70.3% of the same samples tested M. bovis positive by the IMS-based tests. Results clearly demonstrate that not only are the IMS-based methods more rapid but they have greater detection sensitivity than the culture approach currently used for the detection of M. bovis infection in cattle. Adoption of the IMS-based methods for lymph node testing would have the potential to improve M. bovis detection in clinical samples.

  15. Sequence-specific DNA alkylation by tandem Py-Im polyamide conjugates.

    Science.gov (United States)

    Taylor, Rhys Dylan; Kawamoto, Yusuke; Hashiya, Kaori; Bando, Toshikazu; Sugiyama, Hiroshi

    2014-09-01

    Tandem N-methylpyrrole-N-methylimidazole (Py-Im) polyamides with good sequence-specific DNA-alkylating activities have been designed and synthesized. Three alkylating tandem Py-Im polyamides with different linkers, which each contained the same moiety for the recognition of a 10 bp DNA sequence, were evaluated for their reactivity and selectivity by DNA alkylation, using high-resolution denaturing gel electrophoresis. All three conjugates displayed high reactivities for the target sequence. In particular, polyamide 1, which contained a β-alanine linker, displayed the most-selective sequence-specific alkylation towards the target 10 bp DNA sequence. The tandem Py-Im polyamide conjugates displayed greater sequence-specific DNA alkylation than conventional hairpin Py-Im polyamide conjugates (4 and 5). For further research, the design of tandem Py-Im polyamide conjugates could play an important role in targeting specific gene sequences. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. SISTEMAS MULTIMEDIA BASADOS EN PROTOCOLO IP IMS APLICADOS A SERVICIOS LTE DE 4G

    Directory of Open Access Journals (Sweden)

    Edgar Alfonso Cipagauta Pedraza

    2013-01-01

    Full Text Available Este artículo presenta de una manera sencilla, el sistema creado para soportar los servicios de multimedia dentro de red de nueva generación (NGN llamada IP Multimedia Subsystem (IMS a la vez que se explica su relación con la tecnología Long Term Evolution (LTE definida por el 3GPP en su release 8. IMS se trata de una arquitectura integrada en el núcleo de red para ofrecer servicios multimediales de audio y video sobre una infraestructura. Entonces ahora, los servicios prestados pasarán a ser ofrecidos a través de IP IMS y será la piedra angular en donde estos servicios se generarán y se ofrecerán. LTE es sin duda un impulsor de IMS, pero hay otros factores que empiezan a favorecer y a plantear un modelo de negocio favorable para la arquitectura multimedia. IMS está orientado a habilitar la convergencia de servicios, combinando el crecimiento de la Internet con el de las comunicaciones móviles, desde cualquier ubicación y método de forma continua y permanente.

  17. Influence of the ionic liquid [C4mpy][Tf2N] on the structure of the miniprotein Trp-cage.

    Science.gov (United States)

    Baker, Joseph L; Furbish, Jeffrey; Lindberg, Gerrick E

    2015-11-01

    We examine the effect of the ionic liquid [C4mpy][Tf2N] on the structure of the miniprotein Trp-cage and contrast these results with the behavior of Trp-cage in water. We find the ionic liquid has a dramatic effect on Trp-cage, though many similarities with aqueous Trp-cage are observed. We assess Trp-cage folding by monitoring root mean square deviation from the crystallographic structure, radius of gyration, proline cis/trans isomerization state, protein secondary structure, amino acid contact formation and distance, and native and non-native contact formation. Starting from an unfolded configuration, Trp-cage folds in water at 298 K in less than 500 ns of simulation, but has very little mobility in the ionic liquid at the same temperature, which can be ascribed to the higher ionic liquid viscosity. At 365 K, the mobility of the ionic liquid is increased and initial stages of Trp-cage folding are observed, however Trp-cage does not reach the native folded state in 2 μs of simulation in the ionic liquid. Therefore, in addition to conventional molecular dynamics, we also employ scaled molecular dynamics to expedite sampling, and we demonstrate that Trp-cage in the ionic liquid does closely approach the aqueous folded state. Interestingly, while the reduced mobility of the ionic liquid is found to restrict Trp-cage motion, the ionic liquid does facilitate proline cis/trans isomerization events that are not seen in our aqueous simulations. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Multi-dimensional boron transport modeling in subchannel approach: Part I. Model selection, implementation and verification of COBRA-TF boron tracking model

    Energy Technology Data Exchange (ETDEWEB)

    Ozdemir, Ozkan Emre, E-mail: ozdemir@psu.edu [Department of Mechanical and Nuclear Engineering, The Pennsylvania State University, University Park, PA 16802 (United States); Avramova, Maria N., E-mail: mna109@psu.edu [Department of Mechanical and Nuclear Engineering, The Pennsylvania State University, University Park, PA 16802 (United States); Sato, Kenya, E-mail: kenya_sato@mhi.co.jp [Mitsubishi Heavy Industries (MHI), Kobe (Japan)

    2014-10-15

    Highlights: ► Implementation of multidimensional boron transport model in a subchannel approach. ► Studies on cross flow mechanism, heat transfer and lateral pressure drop effects. ► Verification of the implemented model via code-to-code comparison with CFD code. - Abstract: The risk of reflux condensation especially during a Small Break Loss Of Coolant Accident (SB-LOCA) and the complications of tracking the boron concentration experimentally inside the primary coolant system have stimulated and subsequently have been a focus of many computational studies on boron tracking simulations in nuclear reactors. This paper presents the development and implementation of a multidimensional boron transport model with Modified Godunov Scheme within a thermal-hydraulic code based on a subchannel approach. The cross flow mechanism in multiple-subchannel rod bundle geometry as well as the heat transfer and lateral pressure drop effects are considered in the performed studies on simulations of deboration and boration cases. The Pennsylvania State University (PSU) version of the COBRA-TF (CTF) code was chosen for the implementation of three different boron tracking models: First Order Accurate Upwind Difference Scheme, Second Order Accurate Godunov Scheme, and Modified Godunov Scheme. Based on the performed nodalization sensitivity studies, the Modified Godunov Scheme approach with a physical diffusion term was determined to provide the best solution in terms of precision and accuracy. As a part of the verification and validation activities, a code-to-code comparison was carried out with the STAR-CD computational fluid dynamics (CFD) code and presented here. The objective of this study was two-fold: (1) to verify the accuracy of the newly developed CTF boron tracking model against CFD calculations; and (2) to investigate its numerical advantages as compared to other thermal-hydraulics codes.

  19. Effect of social odor context on the emission of isolation-induced ultrasonic vocalizations in the BTBR T+tf/J mouse model for autism

    Science.gov (United States)

    Wöhr, Markus

    2015-01-01

    An important diagnostic criterion for social communication deficits in autism spectrum disorders (ASD) are difficulties in adjusting behavior to suit different social contexts. While the BTBR T+tf/J (BTBR) inbred strain of mice is one of the most commonly used mouse models for ASD, little is known about whether BTBR mice display deficits in detecting changes in social context and their ability to adjust to them. Here, it was tested therefore whether the emission of isolation-induced ultrasonic vocalizations (USV) in BTBR mouse pups is affected by the social odor context, in comparison to the standard control strain with high sociability, C57BL/6J (B6). It is known that the presence of odors from mothers and littermates leads to a calming of the isolated mouse pup, and hence to a reduction in isolation-induced USV emission. In accordance with their behavioral phenotypes with relevance to all diagnostic core symptoms of ASD, it was predicted that BTBR mouse pups would not display a calming response when tested under soiled bedding conditions with home cage bedding material containing maternal odors, and that similar isolation-induced USV emission rates would be seen in BTBR mice tested under clean and soiled bedding conditions. Unexpectedly, however, the present findings show that BTBR mouse pups display such a calming response and emit fewer isolation-induced USV when tested under soiled as compared to clean bedding conditions, similar to B6 mouse pups. Yet, in contrast to B6 mouse pups, which emitted isolation-induced USV with shorter call durations and lower levels of frequency modulation under soiled bedding conditions, social odor context had no effect on acoustic call features in BTBR mouse pups. This indicates that the BTBR mouse model for ASD does not display deficits in detecting changes in social context, but has a limited ability and/or reduced motivation to adjust to them. PMID:25852455

  20. An IMS Station life cycle from a sustainment point of view

    Science.gov (United States)

    Brely, Natalie; Gautier, Jean-Pierre; Foster, Daniel

    2014-05-01

    The International Monitoring System (IMS) is to consist of 321 monitoring facilities, composed of four different technologies with a variety of designs and equipment types, deployed in a range of environments around the globe. The International Monitoring System is conceived to operate in perpetuity through maintenance, replacement and recapitalization of IMS facilities' infrastructure and equipment when the end of service life is reached [CTBT/PTS/INF.1163]. Life Cycle techniques and modellization are being used by the PTS to plan and forecast life cycle sustainment requirements of IMS facilities. Through historical data analysis, Engineering inputs and Feedback from experienced Station Operators, the PTS currently works towards increasing the level of confidence on these forecasts and sustainment requirements planning. Continued validation, feedback and improvement of source data from scientific community and experienced users is sought and essential in order to ensure limited effect on data availability and optimal costs (human and financial).

  1. Gas hydrates and permafrost in continental northern West Siberia; Gashydrate und Permafrost im kontinentalen noerdlichen Westsibirien

    Energy Technology Data Exchange (ETDEWEB)

    Cramer, B. [Bundesanstalt fuer Geowissenschaften und Rohstoffe, Hannover (Germany); Braun, A.; Poelchau, H.S. [Forschungszentrum Juelich (Germany). Inst. fuer Erdoel und Organische Geochemie; Littke, R. [RWTH Aachen (Germany). Lehrstuhl fuer Geologie, Geochemie und Lagerstaetten des Erdoels und der Kohle

    1997-12-31

    The largest natural gas pool in the world is located in northern part of the West Siberian Basin. During the Quaternary this reservoir became overlaid with several hundreds of metres of permafrost. The pressure and temperature conditions prevailing under this permafrost zone have led to the development of gas hydrates. As far as is known today there is no genetic relationship between the formation of the gas pool and the development of gas hydrates. The present contribution deals with these questions in detail. (MSK) [Deutsch] Im Nordteil des westsibirischen Beckens liegt die groesste Erdgaslagerstaette der Erde. Darueber hat sich im Quartaer ein mehrere hundert Meter maechtiger Permafrost gebildet. Die unter der Premafrostzone herrschenden Druck-und Temperaturbedingungen ermoeglichten die Bildung von Gashydraten. Nach heutigen Erkenntnisse besteht kein genetischer Zusammenhang zwischen Lagerstaettenbildung und Gashydraten. Im Folgenden werden Einzelheiten geschildert.

  2. Down-conversion IM-DD RF photonic link utilizing MQW MZ modulator.

    Science.gov (United States)

    Xu, Longtao; Jin, Shilei; Li, Yifei

    2016-04-18

    We present the first down-conversion intensity modulated-direct detection (IM-DD) RF photonic link that achieves frequency down-conversion using the nonlinear optical phase modulation inside a Mach-Zehnder (MZ) modulator. The nonlinear phase modulation is very sensitive and it can enable high RF-to-IF conversion efficiency. Furthermore, the link linearity is enhanced by canceling the nonlinear distortions from the nonlinear phase modulation and the MZ interferometer. Proof-of-concept measurement was performed. The down-conversion IM-DD link demonstrated 28dB improvement in distortion levels over that of a conventional IM-DD link using a LiNbO3 MZ modulator.

  3. The expression of Hedgehog genes (Ihh, Dhh) and Hedgehog target genes (Ptc1, Gli1, Coup-TfII) is affected by estrogenic stimuli in the uterus of immature female rats.

    Science.gov (United States)

    Katayama, Seiichi; Ashizawa, Koji; Gohma, Hiroshi; Fukuhara, Tadahiro; Narumi, Kazunori; Tsuzuki, Yasuhiro; Tatemoto, Hideki; Nakada, Tadashi; Nagai, Kenji

    2006-12-15

    The objective of this study was to investigate the effects of estrogen receptor (ER) agonists and an ER antagonist on the expression of Hedgehog genes (Indian hedgehog: Ihh; Desert hedgehog: Dhh) and Hedgehog target genes (Patched 1: Ptc1; glioma-associated oncogene homolog 1: Gli1; chicken ovalbumin upstream promoter transcription factor II: Coup-TfII) in the rat uterus. Immature female rats were administered once with 17alpha-ethynyl estradiol (EE, an ER agonist), propyl pyrazole triole (PPT, an ERalpha-selective agonist), diarylpropionitrile (DPN, an ERbeta-selective agonist), or ICI 182,780 (an ER antagonist). Expression of mRNA for Ihh, Dhh, and Ptc1 was dose-dependently downregulated by EE in the uterus of immature rats, mediated by ER as confirmed by coadministration of ICI 182,780. The mRNA expression levels of Ptc1, Gli1, and Coup-TfII were simultaneously downregulated during the period in which the mRNA expression levels of Ihh and Dhh were downregulated in the uterus after administration of EE. PPT downregulated the transcription of Ihh, Dhh, Ptc1, Gli1, and Coup-TfII, indicating that expression of these genes was regulated by the ERalpha-dependent pathway. DPN also downregulated the transcription of Ihh and Dhh, although the effect was weaker than that of PPT, indicating that the regulation of uterine Ihh and Dhh transcription was also affected by the ERbeta-dependent pathway. These results suggest that the expression of Hedgehog genes (Ihh, Dhh) and Hedgehog target genes (Ptc1, Gli1, Coup-TfII) is affected by estrogenic stimuli in the uterus of immature female rats.

  4. The expression of Hedgehog genes (Ihh, Dhh) and Hedgehog target genes (Ptc1, Gli1, Coup-TfII) is affected by estrogenic stimuli in the uterus of immature female rats

    International Nuclear Information System (INIS)

    Katayama, Seiichi; Ashizawa, Koji; Gohma, Hiroshi; Fukuhara, Tadahiro; Narumi, Kazunori; Tsuzuki, Yasuhiro; Tatemoto, Hideki; Nakada, Tadashi; Nagai, Kenji

    2006-01-01

    The objective of this study was to investigate the effects of estrogen receptor (ER) agonists and an ER antagonist on the expression of Hedgehog genes (Indian hedgehog: Ihh; Desert hedgehog: Dhh) and Hedgehog target genes (Patched 1: Ptc1; glioma-associated oncogene homolog 1: Gli1; chicken ovalbumin upstream promoter transcription factor II: Coup-TfII) in the rat uterus. Immature female rats were administered once with 17α-ethynyl estradiol (EE, an ER agonist), propyl pyrazole triole (PPT, an ERα-selective agonist), diarylpropionitrile (DPN, an ERβ-selective agonist), or ICI 182,780 (an ER antagonist). Expression of mRNA for Ihh, Dhh, and Ptc1 was dose-dependently downregulated by EE in the uterus of immature rats, mediated by ER as confirmed by coadministration of ICI 182,780. The mRNA expression levels of Ptc1, Gli1, and Coup-TfII were simultaneously downregulated during the period in which the mRNA expression levels of Ihh and Dhh were downregulated in the uterus after administration of EE. PPT downregulated the transcription of Ihh, Dhh, Ptc1, Gli1, and Coup-TfII, indicating that expression of these genes was regulated by the ERα-dependent pathway. DPN also downregulated the transcription of Ihh and Dhh, although the effect was weaker than that of PPT, indicating that the regulation of uterine Ihh and Dhh transcription was also affected by the ERβ-dependent pathway. These results suggest that the expression of Hedgehog genes (Ihh, Dhh) and Hedgehog target genes (Ptc1, Gli1, Coup-TfII) is affected by estrogenic stimuli in the uterus of immature female rats

  5. Measuring cognitive change with ImPACT: the aggregate baseline approach.

    Science.gov (United States)

    Bruce, Jared M; Echemendia, Ruben J; Meeuwisse, Willem; Hutchison, Michael G; Aubry, Mark; Comper, Paul

    2017-11-01

    The Immediate Post-Concussion Assessment and Cognitive Test (ImPACT) is commonly used to assess baseline and post-injury cognition among athletes in North America. Despite this, several studies have questioned the reliability of ImPACT when given at intervals employed in clinical practice. Poor test-retest reliability reduces test sensitivity to cognitive decline, increasing the likelihood that concussed athletes will be returned to play prematurely. We recently showed that the reliability of ImPACT can be increased when using a new composite structure and the aggregate of two baselines to predict subsequent performance. The purpose of the present study was to confirm our previous findings and determine whether the addition of a third baseline would further increase the test-retest reliability of ImPACT. Data from 97 English speaking professional hockey players who had received at least 4 ImPACT baseline evaluations were extracted from a National Hockey League Concussion Program database. Linear regression was used to determine whether each of the first three testing sessions accounted for unique variance in the fourth testing session. Results confirmed that the aggregate baseline approach improves the psychometric properties of ImPACT, with most indices demonstrating adequate or better test-retest reliability for clinical use. The aggregate baseline approach provides a modest clinical benefit when recent baselines are available - and a more substantial benefit when compared to approaches that obtain baseline measures only once during the course of a multi-year playing career. Pending confirmation in diverse samples, neuropsychologists are encouraged to use the aggregate baseline approach to best quantify cognitive change following sports concussion.

  6. Miniature GC-Minicell Ion Mobility Spectrometer (IMS) for In Situ Measurements in Astrobiology Planetary Missions

    Science.gov (United States)

    Kojiro, Daniel R.; Stimac, Robert M.; Kaye, William J.; Holland, Paul M.; Takeuchi, Norishige

    2006-01-01

    Astrobiology flight experiments require highly sensitive instrumentation for in situ analysis of volatile chemical species and minerals present in the atmospheres and surfaces of planets, moons, and asteroids. The complex mixtures encountered place a heavy burden on the analytical instrumentation to detect and identify all species present. The use of land rovers and balloon aero-rovers place additional emphasis on miniaturization of the analytical instrumentation. In addition, smaller instruments, using tiny amounts of consumables, allow the use of more instrumentation and/or ionger mission life for stationary landers/laboratories. The miniCometary Ice and Dust Experiment (miniCIDEX), which combined Gas Chromatography (GC) with helium Ion Mobility Spectrometry (IMS), was capable of providing the wide range of analytical information required for Astrobiology missions. The IMS used here was based on the PCP model 111 IMS. A similar system, the Titan Ice and Dust Experiment (TIDE), was proposed as part of the Titan Orbiter Aerorover Mission (TOAM). Newer GC systems employing Micro Electro- Mechanical System (MEMS) based technology have greatly reduced both the size and resource requirements for space GCs. These smaller GCs, as well as the continuing miniaturization of Astrobiology analytical instruments in general, has highlighted the need for smaller, dry helium IMS systems. We describe here the development of a miniature, MEMS GC-IMS system (MEMS GC developed by Thorleaf Research Inc.), employing the MiniCell Ion Mobility Spectrometer (IMS), from Ion Applications Inc., developed through NASA's Astrobiology Science and Technology Instrument Development (ASTID) Program and NASA s Small Business Innovative Research (SBIR) Program.

  7. [Christofer Herrmann. Kloster und Burg - die architektur des Deutschens Ordens im Pressen und Livland. In : Glaube, Macht und Pracht. GeistlicheGemeinschaften des Ostseeraums im Zeitalter der Backsteingotik] / Dennis Hortmuth

    Index Scriptorium Estoniae

    Hortmuth, Dennis

    2011-01-01

    Arvustus: Christofer Herrmann. Kloster und Burg - die Architektur des Deutschen Ordens in Preussen und Livland. In : Glaube, Macht und Pracht. GeistlicheGemeinschaften des Ostseeraums im Zeitalter der Backsteingotik (=Archäologie und Geschichte im Ostseeraum; Archaeology and History of the Baltic 6) Rahden : Verlag Marie Leidorf, 2009. S. 209-219. Saksa Ordu arhitektuurist Preisi- ja Liivimaal

  8. Veterinary applications of ionising radiation HERCA Task Force on Veterinary Applications. Main results of the Questionnaire 'National regulatory requirements with regard to veterinary medical applications of ionising radiation' and conclusions of the TF

    International Nuclear Information System (INIS)

    Van Bladel, Lodewijk; Berlamont, Jolien; Michalczak, Herbert; Balogh, Lajos; Peremans, Kathelijne

    2013-11-01

    In the fall of 2012, the subject of radiation protection in veterinary medicine was raised during the meeting of the HERCA Board. Issues with regard to this subject had been brought to the attention of HERCA by the European College of Veterinary Diagnostic Imaging (ECVDI). In October 2012, the Board decided to charge a small Task Force (TF) to further explore the issues in this field. This TF drew up a questionnaire which looked at the general radiation protection regulatory requirements in veterinary medicine applications of ionizing radiation. The results of this study showed large differences in the requirements applicable in the HERCA member countries. The TF also noticed the increasing use of more complex imaging procedures and of different radio-therapeutic modalities, which may imply greater risks of exposure of humans to ionising radiation. These results were presented during the HERCA Board meeting in Berlin, Germany and on which the Board decided to establish a Working Group on veterinary applications of ionising radiations (WG Vet). The main results of the Questionnaire 'National regulatory requirements with regard to veterinary medicine applications of ionising radiation' is attached in Appendix

  9. Datamart use for complex data retrieval in an ArcIMS application

    Energy Technology Data Exchange (ETDEWEB)

    Scherma, S. (Steven); Bolivar, Stephen L.

    2004-01-01

    This paper describes the use of datamarts and data warehousing concepts to expedite retrieval and display of complex attribute data from multi-million record databases. Los Alamos National Laboratory has developed an Internet application (SMART) using ArcIMS that relies on datamarts to quickly retrieve attribute data, associated with, but not contained within GIS layers. The volume of data and the complex relationships within the transactional database made data display within ArcIMS impractical without the use of datamarts. The technical issues and solutions involved in the development are discussed.

  10. Application of Ion Mobility Spectrometry (IMS) in forensic chemistry and toxicology with focus on biological matrices

    Science.gov (United States)

    Bernhard, Werner; Keller, Thomas; Regenscheit, Priska

    1995-01-01

    The IMS (Ion Mobility Spectroscopy) instrument 'Ionscan' takes advantage of the fact that trace quantities of illicit drugs are adsorbed on dust particles on clothes, in cars and on other items of evidence. The dust particles are collected on a membrane filter by a special attachment on a vacuum cleaner. The sample is then directly inserted into the spectrometer and can be analyzed immediately. We show casework applications of a forensic chemistry and toxicology laboratory. One new application of IMS in forensic chemistry is the detection of psilocybin in dried mushrooms without any further sample preparation.

  11. Female teams im eSport: Re-Konstruktion der Kategorie Geschlecht

    OpenAIRE

    Streubel, Anett

    2010-01-01

    "Das Ziel dieses Papers ist es, die Herausbildung von "female Teams" im eSport zu untersuchen. Das Hauptaugenmerk liegt hierbei auf Rekonstruktionsmechanismen der Kategorie Geschlecht, welche durch Sprache und Diskurse gebildet, erlernt und fortgeführt werden. Der Anteil der Spielerinnen, die das Computerspielen als Sport betreiben, wächst stetig an - deshalb soll in dieser Studie der Profibereich des eSport näher betrachtet werden. In einem Tätigkeitsfeld, in dem nicht der Körper im Mittelpu...

  12. Die biene und ihre produkte in der kunst und im alltagsleben (Fruhchristliche und byzantinische Zeit

    Directory of Open Access Journals (Sweden)

    Liveri Angeliki

    2010-01-01

    Full Text Available Die vorliegende Arbeit ist in zwei Teile geteilt: den kunst- und kulturhistorischen Teil. Im ersten Teil werden Darstellungen uber Bienen Bienenzucht, Honig und Wachs seit der fruhchristlichen bis zur spatbyzantinischen Zeit vorgefuhrt. Daher ist es als Beitrag in der "Ikonographie" der Biene wahrend dieser Zeit zu verstehen. Im kulturhistorischen Teil werden Informationen uber die Bienenzucht, den Handel mit Honig und Wachs sowie ihre vielfaltige Anwendung von der byzantinischen Gesellschaft an Hand der primaren Quellen, des Standes der Forschung und der archaologischen Funden erwahnt. Damit ist erwunscht ein moglichst gutes Bild der byzantinischen Bienenzucht wieder zu geben und die Nutzung der Bienenprodukte in Byzanz anschaulich zu machen.

  13. Quad-Polarization Transmission for High-Capacity IM/DD Links

    DEFF Research Database (Denmark)

    Estaran Tolosa, Jose Manuel; Castaneda, Mario A. Usuga; Porto da Silva, Edson

    2014-01-01

    We report the first experimental demonstration of IM/DD links usi ng four states of polarization. Fiber - Induced polarization rotation is compensated with a simple tracking algorithm operating on the Stokes space. The principle is prove n at 128 Gb/s over 2 - km SSMF......We report the first experimental demonstration of IM/DD links usi ng four states of polarization. Fiber - Induced polarization rotation is compensated with a simple tracking algorithm operating on the Stokes space. The principle is prove n at 128 Gb/s over 2 - km SSMF...

  14. Power-efficient method for IM-DD optical transmission of multiple OFDM signals.

    Science.gov (United States)

    Effenberger, Frank; Liu, Xiang

    2015-05-18

    We propose a power-efficient method for transmitting multiple frequency-division multiplexed (FDM) orthogonal frequency-division multiplexing (OFDM) signals in intensity-modulation direct-detection (IM-DD) optical systems. This method is based on quadratic soft clipping in combination with odd-only channel mapping. We show, both analytically and experimentally, that the proposed approach is capable of improving the power efficiency by about 3 dB as compared to conventional FDM OFDM signals under practical bias conditions, making it a viable solution in applications such as optical fiber-wireless integrated systems where both IM-DD optical transmission and OFDM signaling are important.

  15. Reconstrucción Tridimensional de Imágenes Ecocardiográficas

    Directory of Open Access Journals (Sweden)

    Jan Ramírez

    2001-04-01

    Full Text Available

    Las imágenes ecocardiográficas convencionales permiten la evaluación
    anatómica y funcional del corazón; por ser bidimensionales son difíciles de interpretar sin un entrenamiento adecuado; los últimos desarrollos han estado orientados a la reconstrucción del corazón en 3 y 4 dimensiones directamente en el equipo de ultrasonido o usando programas especializados. El objetivo es un software en MATLAB™ para la reconstrucción 3D y 4D de imágenes ecocardiográficas.

     

     

  16. Design of data transportation based on dual-port RAM in IMS system

    International Nuclear Information System (INIS)

    Zhang Guohui; Li Yongping

    2010-01-01

    Ion mobility spectroscopy (IMS) is a rugged, portable, sensitive, low cost, field instrumental technique capable of trace organic detection and monitoring for environmental pollutants, pesticides, explosives, narcotics, and other analytes, hence it is of great significance to social security and stability. High rate data transmission mechanism between DSP processor and ARM core is required in the electronic system of IMS. After careful comparison of UART and dual port RAM, a new design based on dual port RAM that can be applied to other similar systems. (authors)

  17. Modelled and Observed Diurnal SST Signals: "SSTDV:R.EX.-IM.A.M." Project Preliminary Results

    DEFF Research Database (Denmark)

    Karagali, Ioanna; Høyer, Jacob; LeBorgne, Pierre

    2013-01-01

    This study presents some of the preliminary results from the ESA Support To Science Element (STSE) funded project on the Diurnal Variability of the Sea Surface Temperature, regarding its Regional Extend and Implications in Atmospheric Modelling (SSTDV:R.EX.–IM.A.M.). During this phase of the proj......This study presents some of the preliminary results from the ESA Support To Science Element (STSE) funded project on the Diurnal Variability of the Sea Surface Temperature, regarding its Regional Extend and Implications in Atmospheric Modelling (SSTDV:R.EX.–IM.A.M.). During this phase...

  18. Diagnostic evaluatuin of gastrointestinal tumors; Diagnostik bei Tumoren im Gastrointestinaltrakt

    Energy Technology Data Exchange (ETDEWEB)

    Linke, R.; Tatsch, K. [Ludwig-Maximilians-Univ. Muenchen (Germany). Klinik und Poliklinik fuer Nuklearmedizin

    1998-07-01

    neuere radiologische Verfahren auch den Nachweis von Laesionen <1 cm erlaubt. Die PET weist hier ebenfalls eine hohe Sensitivitaet auf, da sich bei einem gesteigerten Glukosemetabolismus auch sehr kleine Herde darstellen lassen. Das sensitivste Verfahren zum Nachweis von Pankreastumoren ist die Endosonographie. Die Frage der Dignitaet kann meist mit der ERCP geklaert werden, aber auch die PET hat hier ihren Stellenwert, insbesondere bei der schwierigen Differentialdiagnose zwischen chronischer Pankreatitis und dem Pankreaskarzinom. Zur OP-Planung ist die konventionelle radiologische Bildgebung unerlaesslich. Bei der Beurteilung der Resektabilitaet kommt es mit der CT oder MRT jedoch in bis zu 40% der Faelle zu Fehleinschaetzungen. Die PET hat auch hier eine wesentlich hoehere Sensitivitaet im Metastasennachweis. (orig.)

  19. Multiprofessionelle Ausbildung im Medizinstudium [Multiprofessional training in medical education

    Directory of Open Access Journals (Sweden)

    Stößel, Ulrich

    2006-05-01

    Full Text Available [english] The MESOP-project - Intredisciplinary cooperation in the health care system (Medicne, Social work, Nursery, which was funded by the ministery for science, research and arts of the Land Baden-Wuerttemberg for the years 1997-2000 aimed amongst others at the development and proving of new teaching and learning modules for health care and social professions. Based on an analysis of comparable former teaching efforts and giving some disambiguation for the terms interdisciplinarity and multiproessionality, this article describes a teaching project which was designed across the borders of the participating universities. Together students from medical faculty of the university of Freiburg (n=59 and students from the university of applied sciences for social work of Esslingen (n=61 took part in several weekend seminaries, which focussed the topic of interdisciplinary cooperation in the health care and social welfare system. The contribution describes the development of this teaching concept during several years of proving and the design of the evaluation process and instruments, which mainly was based on standardised questionnaires and an additional open discussion. The detailed report about the results of the evaluation and their interpretation do not allow to jump to conclusions concerning the transfer into regular teaching practice. But it gets obvious that students from both faculty claim for the integration of this topic into their education. Therefore it seems to be necessary to strengthen the knowledge about other health professionals and to give the possibility of practical exercises for cooperation [german] Das Projekt MESOP - Interdisziplinäre Kooperation im Gesundheitswesen (Medizin, Soziale Arbeit, Pflege, das vom Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg von 1997-2000 gefördert wurde, diente u.a. der Entwicklung und Erprobung neuer Lehr- und Lernformen für Gesundheits- und Sozialberufe. Anknüpfend an

  20. Sinnvolle Lebensführung im Spannungsfeld von Risiko und Sicherheit Die Ethik der Risikominimierung im Lichte von Kierkegaards und Nietzsches Kritik der Moderne

    Directory of Open Access Journals (Sweden)

    Hüsch Sebastian

    2016-07-01

    Full Text Available Der Beitrag betrachtet die für die Gegenwartsgesellschaft charakteristische Orientierung an Sicherheit und Risikovermeidung vor dem Hintergrund der Reflexionen Søren Kierkegaards und Friedrich Nietzsches bezüglich der Abgründigkeit der menschlichen Existenz. Die Untersuchung wirft die Frage auf, ob die Suche nach einem im alltäglichen Sinne verstandenen „guten Leben“ letzten Endes zu Lasten der Möglichkeiten einer als sinnhaft erlebten Existenz geht.

  1. 76 FR 79217 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-IMS Global...

    Science.gov (United States)

    2011-12-21

    ... Production Act of 1993--IMS Global Learning Consortium, Inc. Notice is hereby given that, on November 28....C. 4301 et seq. (``the Act''), IMS Global Learning Consortium, Inc. has filed written notifications..., have been added as parties to this venture. Also, Inclusive Design Research Center, Toronto, Ontario...

  2. 77 FR 54611 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-IMS Global...

    Science.gov (United States)

    2012-09-05

    ... Production Act of 1993--IMS Global Learning Consortium, Inc. Notice is hereby given that, on July 16, 2012... seq. (``the Act''), IMS Global Learning Consortium, Inc. has filed written notifications...; and Lightbox Education, Cheadle, UNITED KINGDOM, have withdrawn as parties to this venture. No other...

  3. 76 FR 34252 - Notice Pursuant to the National Cooperative Research and Production Act of 1993; IMS Global...

    Science.gov (United States)

    2011-06-13

    ... Production Act of 1993; IMS Global Learning Consortium, Inc. Notice is hereby given that, on May 9, 2011... seq. (``the Act''), IMS Global Learning Consortium, Inc. has filed written notifications... Education, Hamar, Norway, have been added as parties to this venture. Also, CTUnion, Seoul, Republic of...

  4. 75 FR 64694 - Approval for Expanded Manufacturing Authority; Foreign-Trade Subzone 33E; DNP IMS America...

    Science.gov (United States)

    2010-10-20

    ... Manufacturing Authority; Foreign-Trade Subzone 33E; DNP IMS America Corporation (Thermal Transfer Ribbon Printer..., grantee of FTZ 33, has requested an expansion of the scope of manufacturing authority on behalf of DNP IMS...-6636, 2/10/2010) and the application has been processed pursuant to the FTZ Act and the Board's...

  5. Season of infectious mononucleosis and risk of multiple sclerosis at different latitudes; the EnvIMS Study.

    Science.gov (United States)

    Lossius, Andreas; Riise, Trond; Pugliatti, Maura; Bjørnevik, Kjetil; Casetta, Ilaria; Drulovic, Jelena; Granieri, Enrico; Kampman, Margitta T; Landtblom, Anne-Marie; Lauer, Klaus; Magalhaes, Sandra; Myhr, Kjell-Morten; Pekmezovic, Tatjana; Wesnes, Kristin; Wolfson, Christina; Holmøy, Trygve

    2014-05-01

    Seasonal fluctuations in solar radiation and vitamin D levels could modulate the immune response against Epstein-Barr virus (EBV) infection and influence the subsequent risk of multiple sclerosis (MS). Altogether 1660 MS patients and 3050 controls from Norway and Italy participating in the multinational case-control study of Environmental Factors In Multiple Sclerosis (EnvIMS) reported season of past infectious mononucleosis (IM). IM was generally reported more frequently in Norway (p=0.002), but was associated with MS to a similar degree in Norway (odds ratio (OR) 2.12, 95% confidence interval (CI) 1.64-2.73) and Italy (OR 1.72, 95% CI 1.17-2.52). For all participants, there was a higher reported frequency of IM during spring compared to fall (p<0.0005). Stratified by season of IM, the ORs for MS were 1.58 in spring (95% CI 1.08-2.31), 2.26 in summer (95% CI 1.46-3.51), 2.86 in fall (95% CI 1.69-4.85) and 2.30 in winter (95% CI 1.45-3.66). IM is associated with MS independently of season, and the association is not stronger for IM during spring, when vitamin D levels reach nadir. The distribution of IM may point towards a correlation with solar radiation or other factors with a similar latitudinal and seasonal variation.

  6. 76 FR 18797 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-IMS Global...

    Science.gov (United States)

    2011-04-05

    ... Production Act of 1993--IMS Global Learning Consortium, Inc. Notice is hereby given that, on March 3, 2011... seq. (``the Act''), IMS Global Learning Consortium, Inc. has filed written notifications... Centre for ICT in Education, Hamar, NORWAY, has been added as a party to this venture. Also, Horizon...

  7. 77 FR 34069 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-IMS Global...

    Science.gov (United States)

    2012-06-08

    ... Production Act of 1993--IMS Global Learning Consortium, Inc. Notice is hereby given that, on May 2, 2012... seq. (``the Act''), IMS Global Learning Consortium, Inc. has filed written notifications... Education has changed its name to Ellucian, Malvern, PA. No other changes have been made in either the...

  8. 77 FR 12881 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-IMS Global...

    Science.gov (United States)

    2012-03-02

    ... Production Act of 1993--IMS Global Learning Consortium, Inc. Notice is hereby given that, on February 6, 2012... seq. (``the Act''), IMS Global Learning Consortium, Inc. has filed written notifications..., Plano, TX; Keller ISD, Keller, TX; Maryland State Department of Education, Baltimore, MD; Measured...

  9. 75 FR 51114 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-IMS Global...

    Science.gov (United States)

    2010-08-18

    ... Production Act of 1993--IMS Global Learning Consortium, Inc. Notice is hereby given that, on July 13, 2010... seq. (``the Act''), IMS Global Learning Consortium, Inc. has filed written notifications...; New York City Department of Education, New York, NY; and Ucompass.com , Inc., Tallahassee, FL, have...

  10. MIP-based enhanced mid-session macro-mobility for IMS-controlled state-full applications

    DEFF Research Database (Denmark)

    Renier, Thibault Julien; Fathi, Hanane; Schwefel, Hans-Peter

    2007-01-01

    , e.g., block unauthorized visiting users. The 3GPP IP Multimedia Subsystem (IMS) is a platform standardized towards network-independent access and session control. The current IMS specifications do not allow for any change of the user's current IP address during an ongoing session, which prevents...

  11. Development of a plug-type IMS-MS instrument and its applications in resolving problems existing in in-situ detection of illicit drugs and explosives by IMS.

    Science.gov (United States)

    Du, Zhenxia; Sun, Tangqiang; Zhao, Jianan; Wang, Di; Zhang, Zhongxia; Yu, Wenlian

    2018-07-01

    Ion mobility spectrometry (IMS) which acts as a rapid analysis technique is widely used in the field detection of illicit drugs and explosives. Due to limited separation abilities of the pint-sized IMS challenges and problems still exist regarding high false positive and false negative responses due to the interference of the matrix. In addition, the gas-phase ion chemistry and special phenomena in the IMS spectra, such one substance showing two peaks, were not identified unambiguously. In order to explain or resolve these questions, in this paper, an ion mobility spectrometry was coupled to a mass spectrometry (IMS-MS). A commercial IMS is embedded in a custom-built ion chamber shell was attached to the mass spectrometer. The faraday plate of IMS was fabricated with a hole for the ions to passing through to the mass spectrometer. The ion transmission efficiency of IMS-MS was optimized by optimizing the various parameters, especially the distance between the faraday plate and the cone of mass spectrum. This design keeps the integrity of the two original instruments and the mass spectrometry still works with multimode ionization source (i.e., IMS-MS, ESI-MS, APCI-MS modes). The illicit drugs and explosive samples were analyzed by the IMS-MS with 63 Ni source. The results showed that the IMS-MS is of high sensitivity. The ionization mechanism of the illicit drug and explosive samples with 63 Ni source were systematically studied. In addition, the interferent which interfered the detection of cocaine was identified as dibutyl phthalate (DBP) by this platform. The reason why the acetone solution of amphetamine showed two peaks was explained. Copyright © 2018 Elsevier B.V. All rights reserved.

  12. Distribución volumétrica, simetría del chorro y diámetro de gotas de las boquillas TF-VS2 Spraying distribution, symmetry of fan and droplet size to spray nozzles TF-VS2

    Directory of Open Access Journals (Sweden)

    R.A.A Román

    2010-12-01

    Full Text Available El conocimiento de las características de las diferentes boquillas de pulverización tiene una importancia imprescindible para la adecuada y correcta recomendación de su uso. El objetivo de este trabajo fue determinar el espaciamiento máximo en la barra horizontal de pulverización, la simetría del chorro y el diámetro de gotas en boquillas de pulverización TF-VS2. El trabajo fue realizado en mesa de deposición, en donde fueron utilizadas las presiones de 100, 200 y 300 kPa en las alturas de trabajo de 40 y 50 cm. La simetría del chorro fue determinada en función de dos metodologías (empírica y trigonométrica. También se determinó el tamaño de las gotas, utilizando el método de difracción de rayos laser, en función de dos caldos de pulverización constituidos por agua y por agua con adyuvante en las tres presiones de trabajo ya descritas. Los espaciamientos máximos entre las boquillas en la barra de pulverización no pueden rebasar los 70 y 82 cm, admitiéndose el CV de un 10% para las alturas de 40 y de 50 cm respectivamente. La mayor presión proporcionó el menor diámetro mediano volumétrico (DMV y la peor uniformidad de gotas, además del mayor porcentaje de gotas susceptibles a deriva, así como también aumentó la simetría entre los chorros.The knowledge of spray distribution pattern and analysis of droplets size of spray hydraulic nozzles turbo Floodjet TF-VS2 to adapt the spacing on spray boom are very important for a proper and correct use and recommendations. The aim of this study was to determine the maximum spacing on the horizontal spraying boom held on a patternator to the tips TF-VS2, under pressures of 100, 200 and 300 kPa in heights of work of 40 and 50 cm. Symmetry of spraying fan was determined due empirical and trigonometric methodology. It was also determined the droplets size by means of laser diffraction, with two spray liquids consisting of water and water plus adjuvant under three work pressures

  13. Images and society (or Images, Society and its Decoding Las imágenes y la sociedad (o las imágenes, la sociedad y su desciframiento

    Directory of Open Access Journals (Sweden)

    Juan Soto Ramírez

    2012-11-01

    Full Text Available

    Common sense, the thinking of the people par excellence, asserts that: a picture is worth a thousand words. This is a big mistake. The images are not carriers of meanings. The images always go through three basic processes are: production, circulation and reception. These processes are always determined in the time and social space. They are always the result of multiple relationships (social, ideological, political, moral, religious, etc., established with them. Always there are so many elements beyond the image, which determines its meaning. The meaning of an image always depends on the relationships established with it in a historical time and space, socially and culturally determined. The images are never alone. To decrypt their meanings, you must first know the symbolic life of the societies in which they appear. Images do not have a single meaning because it depends on the historical and cultural geography which presents. The images always have a close relationship with the society they were born. The Muhammad cartoons not offend everyone equally.


    El sentido común, que es el pensamiento de las colectividades por excelencia, afirma que: una imagen dice más que mil palabras. Lo cual es un grave error. Las imágenes no son portadoras de significados. Las imágenes siempre atraviesan por tres procesos básicos que son: su producción, su circulación y su recepción. Estos procesos siempre están determinados en el tiempo y en el espacio sociales. Su significado siempre es el resultado de múltiples relaciones (sociales, ideológicas, políticas, morales, religiosas, etc., que se establecen con las mismas. Es decir, siempre existen elementos que están más allá de la imagen, que determinan su significado. La manera en cómo se significa una imagen, siempre depende de las relaciones que se establecen con ella en un tiempo histórico y en un espacio, social y culturalmente determinado. Las imágenes nunca están solas. Para

  14. The Aries Program with emphasis on the International Magnetospherics Studies /IMS/-Porcupine Project

    Science.gov (United States)

    Honecker, H. J.

    1976-01-01

    This paper will discuss the present state of the development of the Aries Sounding Rocket System with particular emphasis on the configuration and subsystems required to support the IMS Program. A brief history of the development program will be presented. The results of the first five flights, three successes and two failures, will be presented and the observed performance compared to theoretical performance.

  15. Strukturelle Methoden zur durchgängigen Diagnose digitaler Automobil-Elektronik im Feld

    OpenAIRE

    Cook, Alejandro

    2014-01-01

    Die Fahrzeugtechnik nutzt die aktuellen Entwicklungen der Halbleiterindustrie, um Kunden eine enorme Anzahl ansprechender, komplexer Produkteigenschaften zu bieten. Da traditionelle, funktionale Testverfahren nicht mehr ausreichen, um den diagnostischen Anforderungen im Automobilbereich gerecht zu werden, wird die Analyse von Halbleiterdefekten zu einem wichtigen Aspekt der Qualitätssicherung. Strukturelle Testverfahren stellen bereits eine Schlüsseltechnologie für die erfolgreiche Herstel...

  16. Report of the Results of an IMS LEarning Design Expert Workshop

    NARCIS (Netherlands)

    Neumann, Susanne; Klebl, Michael; Griffiths, David; Hernández-Leo, Davinia; De la Fuente-Valentin, Luis; Hummel, Hans; Brouns, Francis; Derntl, Michael; Oberhuemer, Petra

    2009-01-01

    Neumann, S., Klebl, M., Griffiths, D., Hernández-Leo, D., de la Fuente Valentín, L., Hummel, H., Brouns, F., Derntl, M., & Oberhuemer, P. (2010). Report of the Results of an IMS Learning Design Expert Workshop. International Journal Of Emerging Technologies In Learning (IJET), 5(1), pp.

  17. Low-SNR Capacity of Parallel IM-DD Optical Wireless Channels

    KAUST Repository

    Chaaban, Anas; Rezki, Zouheir; Alouini, Mohamed-Slim

    2016-01-01

    The capacity of parallel intensity-modulation and direct-detection (IM-DD) optical wireless channels with total average intensity and per-channel peak intensity constraints is studied. The optimal intensity allocation at low signal-to-noise ratio

  18. A Chinese translation of IMS Learning Design Best Practice and Implementation Guide (draft)

    NARCIS (Netherlands)

    Gong, Yufeng

    2006-01-01

    Many Chinese researchers, system developers and e-learning practitioners have difficulties to understand IMS LD correctly because of language barriers. The main aim of this translation is to help chinese people to overcome the difficulties. It is also expected that this translation can launch into a

  19. Die Alpen als "Berg von Leichen und Schmerz" - Erinnerung und Dialog im literarischen Raum Elfriede Jelineks

    DEFF Research Database (Denmark)

    Ortner, Jessica

    2014-01-01

    “ Räumlichkeit im Sinne Gérard Genettes, die „bedeutete“ Landschaft der Alpen zu einer Gedächtnisarchitektur umbildet. In ihren Texten stellt Jelinek zwei grundsätzlich verschiedene Semantisierungen der Alpen in ein dialogisches Verhältnis (Bachtin): Die Semantisierung der Alpen als Touristenparadies und...

  20. imDEV: a graphical user interface to R multivariate analysis tools in Microsoft Excel

    Science.gov (United States)

    Interactive modules for data exploration and visualization (imDEV) is a Microsoft Excel spreadsheet embedded application providing an integrated environment for the analysis of omics data sets with a user-friendly interface. Individual modules were designed to provide toolsets to enable interactive ...