Status of APE projects

CERN Document Server

Alfieri, R; Onofri, E; Bartoloni, A; Battista, C; Cabibbo, Nicola; Cosimi, M; Lonardo, A; Michelotti, A; Proietti, B; Rapuano, F; Rossetti, D; Sacco, G; Tassa, S; Torelli, M; Vicini, P; Pène, O; Errico, W; Magazzù, G; Sartori, L; Schiiano, F; Tripiccione, R; De Riso, P; Petronzio, Roberto; Destri, C; Frezzotti, R; Marchesini, G; Gensch, Ulrich; Jansen, K; Kretzschmann, A; Leich, H; Paschedag, N; Pleiter, D; Schwendicke, U; Simma, H; Sommer, Rainer; Sulanke, K; Wegner, P; Fucci, A; Martin, B; Pech, J; Panizzi, E; Petricola, A

2001-01-01

This talk is divided in two parts. In the first part, we will summarize the status of the APEmille project that will be completed by the end of the year. We will then devote the rest of the talk to the description of a new project for a multi-TeraFlop machine, ape NEXT. The interested reader will find a much more detailed discussion of all the items touched upon here in the full proposal of the project that will shortly appear on hep-lat. (9 refs).

Status of the apeNEXT project

CERN Document Server

Ammendola, R.; Boucaud, Philippe; Cabibbo, N.; Di Carlo, F.; De Pietri, R.; Di Renzo, F.; Errico, W.; Fucci, A.; Guagnelli, M.; Kaldass, H.; Lonardo, A.; de Luca, S.; Micheli, J.; Morenas, V.; Pene, O.; Petronzio, R.; Palombi, F.; Pleiter, D.; Paschedag, N.; Rapuano, F.; De Riso, P.; Rossetti, D.; Salamon, A.; Salina, G.; Sartori, L.; Schifano, F.; Simma, H.; Tripiccione, R.; Vicini, P.; Boucaud, Ph.; 10.1016/S0920-5632(03)01755-9

2003-01-01

We present the current status of the apeNEXT project. Aim of this project is the development of the next generation of APE machines which will provide multi-teraflop computing power. Like previous machines, apeNEXT is based on a custom designed processor, which is specifically optimized for simulating QCD. We discuss the machine design, report on benchmarks, and give an overview on the status of the software development.

EBT-P project status report

International Nuclear Information System (INIS)

1983-11-01

This Elmo Bumpy Torus Report describes the status of the EBT-P Project in September 1983 after phasedown of the Title II design effort. The report is intended to be a principle source of guidance in the event of a decision to resume work on the project

Transformation of carbon tetrachloride in an anaerobic packed-bed reactor without addition of another electron donor

NARCIS (Netherlands)

de Best, JH; Hunneman, P; Doddema, HJ; Janssen, DB; Harder, W; Doddema, Hans J.

1999-01-01

Carbon tetrachloride (52 mu M) was biodegraded for more than 72% in an anaerobic packed-bed reactor without addition of an external electron donor. The chloride mass balance demonstrated that all carbon tetrachloride transformed was completely dechlorinated. Chloroform and dichloromethane were

Transformation of carbon tetrachloride in an anaerobic packed-bed reactor without addition of another electron donor

NARCIS (Netherlands)

Best, J.H. de; Hunneman, P.; Doddema, H.J.; Janssen, D.B.; Harder, W.

1999-01-01

Carbon tetrachloride (52 μM) was biodegraded for more than 72% in an anaerobic packed-bed reactor without addition of an external electron donor. The chloride mass balance demonstrated that all carbon tetrachloride transformed was completely dechlorinated. Chloroform and dichloromethane were

Effects of ethanol and carbon tetrachloride upon vitamin A status of rats

International Nuclear Information System (INIS)

McCauley, K.; Prabhudesai, M.; Erdman, J.W. Jr.

1986-01-01

The effects of ethanol (ET) and carbon tetrachloride (CCL 4 ) upon tissue vitamin A, liver lipids, liver cytochrome P 450 and hepatic morphology were investigated. After a two week feeding period, young male rats were divided into four groups. For 5 weeks one group of rats (n=18) received ET in liquid diets (30% of calories) while another (n=8) was exposed to CCL 4 inhalation twice a week along with phenobarbitol in the diet. All groups received the NRC recommended level for vitamin A. Comparison of ET and its pair-fed control group revealed; decreased hepatic vitamin A, no change in serum vitamin A, increased % liver lipid and cytochrome P 450 with minimal fat accumulation in hepatocytes. Comparison of CCL 4 group with pair-fed controls showed; increased serum vitamin A, decreased hepatic vitamin A, increased cytochrome P 450 , marked hepatic fat accumulation, hepatic cell necrosis and early cirrhosis. Thus, CCL 4 , which is a more potent hepatotoxin as evidenced by a more elevated cytochrome P 450 and distorted liver morphology, not only reduced liver vitamin A, but also increased serum vitamin A. The hepatic response to CCL 4 may mimic a more cirrhotic condition such as that resulting from longer-termed ET intake

The Effects of Silymarin on Oxidative Status and Bone Characteristics in Japanese Quail Subjected to Oxidative Stress Induced by Carbon Tetrachloride

Directory of Open Access Journals (Sweden)

Moradi F

2017-10-01

Full Text Available This experiment was conducted to assess the effects of Silymarin on oxidative status, bone characteristics, and some blood parameters in Japanese quail subjected to oxidative stress induced by carbon tetrachloride (CCl4. The experiment was performed as a completely randomized design with four replicates, each with 30 birds, using a 2 × 2 factorial arrangement with two doses of Silymarin (0 and 1 mL/kg BW and CCl4 (0 and 1 mL/kg BW. Results revealed that the interaction between Silymarin and CCl4on concentrations of total cholesterol, triglycerides, glucose, albumin, calcium, and alkaline phosphatase were significant (P < 0.05. In contrast, concentrations of phosphorus, total protein, and high density lipoprotein-cholesterol in blood serum did not differ between experimental treatments. Experimental treatments had a significant effect on superoxide dismutase activity in blood serum (P < 0.05, but not on glutathione peroxide activity and malondialdehyde concentration. Experimental treatments significantly affected the weight, thickness, and external and internal diameters of tibia bone (P < 0.05, but not its length, ash, volume, and density. This study shows that Silymarin has potential to attenuate adverse effects of oxidative stress induced by CCl4 in Japanese quail.

Liquid structure of vanadium tetrachloride from neutron diffraction study

International Nuclear Information System (INIS)

Gopala Rao, R.V.; Satpathy, B.M.

1982-01-01

Assuming the separation of the intermolecular scattering function into the radial and angular parts and using Egelstaff et al's orientational model for tetrachlorides, the structure of liquid vanadium tetrachloride has been studied. It has been observed that such a separation is approximate for this liquid and the introduction of a third correction term is required to account for the molecular structure function. The chlorine-chlorine partial structure and effective angle-averaged intermolecular chlorine-chlorine potential in the liquid has been evaluated. Without taking the third correction term, introduced to generate theoretically the molecular structure function, the centre structure function has been obtained in an approximate way from the experimentally observed molecular structure function and from it the centre radial distribution function, centre direct correlation function and the angle-averaged vanadium-vanadium effective potential has been evaluated. (author)

In situ bioremediation for the Hanford carbon tetrachloride plume. Innovative technology summary report

International Nuclear Information System (INIS)

1999-04-01

The 200 Area at Hanford (also called the Central Plateau) contains approximately 817 waste sites, 44 facilities to be demolished, and billions of gallons of contaminated groundwater resulting from chemical processing plants and associated waste facilities (e.g., waste tanks). From 1955 to 1973, carbon tetrachloride, nitrate, and other materials were discharged to subsurface liquid waste disposal facilities in the 200 Area. As much as 600,000 kilograms of carbon tetrachloride may have entered the soil column and a portion of this has contaminated the underlying aquifer. In Situ Bioremediation for the Hanford Carbon Tetrachloride Plume (ISB), which is the term used in this report for an in situ treatment process using indigenous micro-organisms with a computer based Accelerated Bioremediation Design Tool (ABDT), remediates groundwater contaminated with volatile organic compounds (VOCs) and nitrates under anaerobic conditions. ISB involves the injection of nutrients into the groundwater and subsequent extraction and re-injection of the groundwater to provide nutrient distribution in the aquifer

Status of CSNS project

International Nuclear Information System (INIS)

Zhang, J.; Fu, S.N.; Chen, H.S.

2015-01-01

The China Spallation Neutron Source (CSNS) accelerator is designed to accelerate proton beam pulses to 1.6 GeV at 25 Hz repetition rate, striking a solid metal target to produce spallation neutrons. The accelerator provides a beam power of 100 kW on the target in the first phase and then 500 kW in the second phase by increasing the average beam intensity 5 times while raising the linac output energy. The project construction has been formally launched in 2011 and it is planned to complete the project in March 2018. It is one of the high intensity proton accelerator projects in the world and it imposes a great challenge to Chinese accelerator community. This presentation will cover the status and challenges of the CSNS project. (author)

Resonance Raman spectroscopy of volatile organics -- Carbon tetrachloride

International Nuclear Information System (INIS)

Barletta, R.E.; Veligdan, J.T.

1994-09-01

Volatile organic chemicals are a class of pollutants which are regulated at very low levels by the EPA. Consequently a need exists as a part of site remediation efforts within DOE to develop technologies which will allow for the in situ monitoring of these chemicals. Resonance Raman spectroscopy is a potential technique to accomplish this if the resonance enhancement is sufficiently high. Carbon tetrachloride was selected as a test case. Measurements under resonance conditions at 248 nm showed an enhancement factor of 2 x 10 4 . Using this value an estimate of the sensitivity for both in situ and remote monitoring of CCl 4 was made. It was concluded that resonance Raman could be used to detect these chemicals at levels of regulatory interest. Future effort directed towards the development of a suitable probe as well as a field-portable system would be desirable. Such effort could be directed towards the solution of a particular monitoring problem within a DOE waste remediation project. Once developed, however, it should be easily generalized to the analysis of other VOC's in other environments

The status of US Teraflops-scale projects

International Nuclear Information System (INIS)

Mawhinney, R.D.

1995-01-01

The current status of United States projects pursuing Teraflops-scale computing resources for lattice field theory is discussed. Two projects are in existence at this time: the Multidisciplinary Teraflops Project, incorporating the physicists of the QCD Teraflops Collaboration, and a smaller project, centered at Columbia, involving the design and construction of a 0.8Teraflops computer primarily for QCD. ((orig.))

Quarterly status of Department of Energy projects

International Nuclear Information System (INIS)

1982-01-01

This Quarterly Status of Department of Energy Projects is prepared by the Office of project and Facilities Management, MA-30. The report is designed to provide Department of Energy (DOE) management officials with a summary of the important baseline data that exists in the DOE project data base. This data base is maintained chiefly from periodic field management reports required by DOE Order 5700.4. Since most of the current estimates in this report are from field project managers, they do not necessarily have full Headquarters approval. The current budget data sheet estimates that appear in the report are considered appropriate for reporting external to the Department and reflect the President's FY 1983 Budget to Congress. Moneys allocated and estimated costs, and the construction status are tabulated for projects under the subject categories of: conservation and renewable energy; defense programs; environmental protection, safety and emergency preparedness; energy research; defense programs; nuclear energy; and management and administration

Hepatoprotective activity of Eugenia jambolana Lam. in carbon tetrachloride treated rats

Science.gov (United States)

Sisodia, S.S.; Bhatnagar, M.

2009-01-01

Objective: To estimate the hepatoprotective effects of the methanolic seed extract of Eugenia jambolana Lam. (Myrtaceae), in Wistar albino rats treated with carbon tetrachloride (CCl4). Materials and Methods: Liver damage in rats treated with CCl4 (1ml/kg/Bw, administered subcutaneously, on alternate days for one week) was studied by assessing parameters such as serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatase (ALP), acid phosphatase (ACP) and bilirubin (total and direct). The effect of co-administration of Eugenia jambolana Lam. (doses 100, 200 and 400 mg/kg p. o.) on the above parameters was investigated. These biochemical observations were supplemented by weight and histological examination of liver sections. Liv.52® was used as positive control. Data were analyzed by one way ANOVA, followed by Scheff's/Dunnett's test. Results: Administration of Eugenia jambolana Lam. (doses 100, 200 and 400 mg/kg p. o.) significantly prevented carbon tetrachloride induced elevation of serum SGOT, SGPT, ALP, ACP and bilirubin (total and direct) level. Histological examination of the liver section revealed hepatic regeneration, after administration of various doses of Eugenia jambolana Lam. The results were comparable to that of Liv.52®. Conclusion: The study suggests preventive action of Eugenia jambolana Lam. in carbon tetrachloride induced liver toxicity. Hepatic cell regeneration process was dose dependent. PMID:20177577

Dietary Antioxidants Effectiveness on Carbon Tetrachloride-Induced Hepatotoxicity in Adult Female Albino Rats

International Nuclear Information System (INIS)

EI-Sherbiny, E.M.; EI-Mahdy, A.A.

2008-01-01

Hepatic toxicity through carbon tetrachloride (CCI 4 ) induced lipid peroxidation was extensively used in experimental models to understand the cellular mechanisms behind oxidative damage and to evaluate the therapeutic potential of drugs and dietary antioxidants. The ameliorative effect of Aloe vera juice and carrot supplementation on hepato carcinogenesis induced by carbon tetrachloride in adult female albino rats was investigated. The carcinogenic process was determined by measuring gamma-glutamyl transpeptidase (GGT), ornithine carbamyl transferase (OCT), thiobarbituric acid reactive substances (TBARs), representing levels of lipid peroxides, and carcinoembryonic antigen (CEA) in the sera of female albino rats. Carbon tetrachloride significantly elevated the serum GGT, OCT activities and the level of TBARs. Administration of Aloe vera leaf juice filtrate after CCl 4 treatment resulted in a non-significant modification in GGT, OCT activities and significantly improved the level of TBARs in comparison with control. Supplementation of carrot to CCI 4 treated animals led to a great amelioration in OCT activity and TBARs level, whereas GGT activity was ameliorated but statistically changed compared to control. There was a non-significant alteration in the level of CEA in all treated groups compared to normal control one

Summary of canister overheating incident at the Carbon Tetrachloride Expedited Response Action site

Energy Technology Data Exchange (ETDEWEB)

Driggers, S.A.

1994-03-10

The granular activated carbon (GAC)-filled canister that overheated was being used to adsorb carbon tetrachloride vapors drawn from a well near the 216-Z-9 Trench, a subsurface disposal site in the 200 West Area of the Hanford Site. The overheating incident resulted in a band of discolored paint on the exterior surface of the canister. Although there was no other known damage to equipment, no injuries to operating personnel, and no releases of hazardous materials, the incident is of concern because it was not anticipated. It also poses the possibility of release of carbon tetrachloride and other hazardous vapors if the incident were to recur. All soil vapor extraction system (VES) operations were halted until a better understanding of the cause of the incident could be determined and controls implemented to reduce the possibility of a recurrence. The focus of this report and the intent of all the activities associated with understanding the overheating incident has been to provide information that will allow safe restart of the VES operations, develop operational limits and controls to prevent recurrence of an overheating incident, and safely optimize recovery of carbon tetrachloride from the ground.

Preliminary evaluation of soil-heating technologies for the 200-ZP-2 carbon tetrachloride expedited response action

International Nuclear Information System (INIS)

Jackson, G.J.; Todd, M.E.; Tranbarger, R.K.

1996-09-01

The 200-ZP-2 Operable Unit is located in the 200 West Area of the Hanford Site. The US Department of Energy has been conducting an expedited response action to treat carbon tetrachloride contamination since 1992 at the operable unit at the direction of the US Environmental Protection Agency and the Washington State Department of Ecology. This document provides an analyses of the soil vapor extraction method used to extract carbon tetrachloride from the soil

The EEE Project status and perspectives

CERN Document Server

Antolini, R; Baldini Ferroli, R; Bencivenni, G; Blanco, F; Bressan, E; Chiavassa, A; Cifarelli, L; Cindolo, F; Coccia, E; De Pasquale, S; Di Giovanni, A; D'Incecco, M; Fabbri, F L; Garbini, M; Gustavino, C; Hatzifotiadou, D; Imponente, G; La Rocca, P; Librizzi, F; Menghetti, H; Miozzi, S; Pappalardo,G S; Piragino, G; Riggi, F; Sartorelli, G; Sbarra, C; Selvi, M; Williams, C; Zichichi, A

2007-01-01

The Extreme Energy Events (EEE) project plans to build and use an array of cosmic ray telescopes for muon detection, distributed over the italian territory. The use of such telescopes, based on Multigap Resistive Plate Chambers (MRPC) will allow the study of cosmic ray showers and the correlation between multiple primaries producing distant showers. The project is also intended to involve high school teams in an advanced research work. The physics items which can be addressed by such array, and the present status and perspectives of the project are here discussed.

A carbon tetrachloride-free synthesis of N-phenyltrifluoroacetimidoyl chloride.

Science.gov (United States)

Smith, Dylan G M; Williams, Spencer J

2017-10-10

N-Phenyltrifluoroacetimidoyl chloride (PTFAI-Cl) is a reagent widely used for the preparation of glycosyl N-phenyltrifluoroacetimidates. However, the most commonly applied method requires carbon tetrachloride, a hepatotoxic reagent that has been phased out under the Montreal Protocol. We report a new synthesis of N-phenyltrifluoroacetimidoyl chloride (PTFAI-Cl) using dichlorotriphenylphosphane and triethylamine. Copyright © 2017. Published by Elsevier Ltd.

Project Radiation protection East. Status Report, July 1997

Energy Technology Data Exchange (ETDEWEB)

Snihs, J.O.; Sundewall, H.; Grapengiesser, S. [STEGRA Consultants (Sweden); Bennerstedt, T. [TeknoTelje (Sweden)

1997-12-01

Project Radiation Protection East is a Swedish program for radiation protection work in Central and Eastern Europe. The projects are assessed, planned and performed in close cooperation with partner organizations in the East. Since 1994 radiation protection cooperation concerning the former Soviet Navy training reactors in Paldiski, Estonia, is included in the project. This report presents a summary over some 140 projects, their status, allocated funds and their distribution over countries and project areas. 12 tabs.

Pinon Pine IGCC project status

International Nuclear Information System (INIS)

Higginbotham, E.B.; Lamarre, L.J.; Glazer, M.

1993-01-01

Sierra Pacific Power Company (SPPCo) intends to build the Pinon Pine Power Project, an integrated coal gasification combined cycle (IGCC) plant at its Tracy Power Station near Reno, Nevada. The plant will burn approximately 800 tons of coal per day to generate electricity in a base load application. The Pinon Project was selected by the U.S. Department of Energy (DOE) for funding under Round IV of the Clean Coal Technology Program. The project will demonstrate the use of the KRW agglomerating fluidized bed gasifer operating in the air blown mode. Hot gas cleanup consisting of particulate and sulfur removal will also be demonstrated. The Cooperative Agreement between SPPCo and the DOE was executed in August 1992. Foster Wheeler USA Corporation (FWUSA) will provide engineering and construction management services. The M.W. Kellogg Company (MWK) will provide engineering of the gasifer and hot gas cleanup systems. A discussion of project progress since the 1992 Clean Coal Technology Conference, design and economic considerations, and current project status is presented

Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats.

Science.gov (United States)

Junnila, M; Barak, A J; Beckenhauer, H C; Rahko, T

1998-10-01

Carbon tetrachloride-injected rats were given liquid diets with and without betaine for 7 d. Hepatic lipidosis was induced by 4 daily injections of carbon tetrachloride (CCl4). Animals were killed and their livers and blood taken for analysis of betaine, S-adenosylmethionine (SAM), betaine homocysteine methyltransferase (BHMT), triglyceride, alanine aminotransferase and aspartate aminotransferase. Liver samples were also processed and stained for histological examination. Supplemental betaine reduced triglyceride in the liver and centrilobular hepatic lipidosis induced by the CCl4 injections. In both the control and experimental groups receiving betaine, liver betaine, BHMT and SAM were significantly higher than in their respective groups not receiving betaine. This study provides evidence that betaine protects the liver against CCl4-induced lipidosis and may be a useful therapeutic and prophylactic agent in ameliorating the harmful effects of CCl4.

Status of LMFBR development project in Japan

International Nuclear Information System (INIS)

Nagane, G.; Akebi, M.; Matsuno, Y.

1987-01-01

Initiation of the LMFBR development project in Japan was decided by the Atomic Energy Commission of Japan in 1966. In 1967, the Power Reactor and Nuclear Fuel Development Corporation (PNC) was established to realize the project as a part of its tasks of a wide scope covering all the reseatch and development activities concerning fuel cycle. In the present paper the status of experimental fast reactor (Joyo), which is the first milestone of the LMFBR project, prototype fast reactor (Monju) and R and D activities supporting the project including that for larger LMFBRs in the future is described. (author)

Belene Nuclear Power Plant project status

International Nuclear Information System (INIS)

Nikolov

2008-01-01

The status of the Belene project with the following main features is described: Reactor type - PWR, Russian Design Plant supplier - ASE, AREVA NP/Siemens Reactor thermal power - 2 x 3012 MW Electric output -2 x 1060 MW Net efficiency - 35 % Capacity factor - 90 % Design Life Time - 60 years

Status of the DIRAC Project

International Nuclear Information System (INIS)

Casajus, A; Ciba, K; Fernandez, V; Graciani, R; Hamar, V; Mendez, V; Poss, S; Sapunov, M; Stagni, F; Tsaregorodtsev, A; Ubeda, M

2012-01-01

The DIRAC Project was initiated to provide a data processing system for the LHCb Experiment at CERN. It provides all the necessary functionality and performance to satisfy the current and projected future requirements of the LHCb Computing Model. A considerable restructuring of the DIRAC software was undertaken in order to turn it into a general purpose framework for building distributed computing systems that can be used by various user communities in High Energy Physics and other scientific application domains. The CLIC and ILC-SID detector projects started to use DIRAC for their data production system. The Belle Collaboration at KEK, Japan, has adopted the Computing Model based on the DIRAC system for its second phase starting in 2015. The CTA Collaboration uses DIRAC for the data analysis tasks. A large number of other experiments are starting to use DIRAC or are evaluating this solution for their data processing tasks. DIRAC services are included as part of the production infrastructure of the GISELA Latin America grid. Similar services are provided for the users of the France-Grilles and IBERGrid National Grid Initiatives in France and Spain respectively. The new communities using DIRAC started to provide important contributions to its functionality. Among recent additions can be mentioned the support of the Amazon EC2 computing resources as well as other Cloud management systems; a versatile File Replica Catalog with File Metadata capabilities; support for running MPI jobs in the pilot based Workload Management System. Integration with existing application Web Portals, like WS-PGRADE, is demonstrated. In this paper we will describe the current status of the DIRAC Project, recent developments of its framework and functionality as well as the status of the rapidly evolving community of the DIRAC users.

Status Report of Projects Activities at CERN

CERN Document Server

Missiaen, Dominique; Dobers, Tobias; Fuchs, Jean-Frederic; Gayde, Jean-Christophe; Jones, Mark; Mainaud Durand, Helene

2014-01-01

Besides the Long Shut-Down 1 (LS1), some projects are still progressing at CERN. Among them, it has to be mentioned LINAC4, a future essential part of the LHC injector chain, AWAKE, a project to verify the approach of using protons to drive a strong wakefield in a plasma, ELENA, a small compact ring for cooling and decelerating antiproton and HIE-Isolde, not to forget the long term studies for CLIC and FCC. This paper describes the status of these projects from the survey and alignment point of view.

Studying preventive effects of Berberisintegerrimaon root on carbon tetrachloride induced hepatotoxicity in broilers

Directory of Open Access Journals (Sweden)

mohammadreza mohammadimalayeri

2013-11-01

Full Text Available Liver diseases and their economic losses have gained more importancealongside the development of integrated poultry industry. Studies have proved hepatotoxicity induced by carbon tetrachloride as one of the best experimental models of hepatotocicity. Barberries have been used widely in traditional medicine.The purpose of the present study was to evaluaterthe preventive effects of Berberisintegerrima root on carbon tetrachloride induced liver lesions in broilers.For this purpose, 80 day old Ross strain broilers were divided randomly to 8 study groupsconsisting of negative control, positive control which received IP 4ml/kg b.w. carbon tetrachloride twice in 25th and 28thdays , treatment controls consisting of 10,20 and 30 grams of  Berberisintegerrima root per kilogram of diet and treatment groups consisting of 10,20 and 30 gr. Of Berberis root / Kg diet + IPcarbontetrachloride 4ml/Kg b.w. twice in 25th and 28th days.At 29th day, blood samples were collected from animals, then they were sacrificed and their liver samples were fixed in 10% formalin solution. The blood samples were sent to laboratory to measure ALT,AST and ALP activities.Biochemical results didn't show any significant changes of ALT,AST and ALP activities between all study groups (P>0.05. Microscopic results showed significant decrease in pathologic lesions of 20 gr Berberis root /Kg diet treatment group in comparison with the positive control group(P

Fast Breeder Project status report, 1974

International Nuclear Information System (INIS)

Hueper, R.

A compilation of the papers read at the Status Report of the Fast Breeder Project at the Karlsruhe Nuclear Research Center on March 26, 1974 is presented. The first papers present a general survey of the present state of research and development work performed by the German, Belgian, and Netherlands research centers on the SNR 300 Prototype Fast Breeder Reactor (Kalkar Nuclear Power Station), on the SNR follow-on program, alternative fuels and coolants and basic problems, on work performed by industry with respect to the licensing procedure and construction of the SNR 300, and on commissioning and the planned conversion of KNK, the Compact Sodium Cooled Nuclear Reactor. The detailed papers deal with results elaborated at the institutes of GfK Karlsruhe, SCK/CEN Mol, RCN Petten, and TNO Apeldoorn. Most of these efforts have been concentrated upon fuel pin and materials development and on the physics and safety of fast reactors. The status report concludes with a reference to the future program under the Project. (U.S.)

Maresin 1, a Proresolving Lipid Mediator, Mitigates Carbon Tetrachloride-Induced Liver Injury in Mice

Directory of Open Access Journals (Sweden)

Ruidong Li

2016-01-01

Full Text Available Maresin 1 (MaR 1 was recently reported to have protective properties in several different animal models of acute inflammation by inhibiting inflammatory response. However, its function in acute liver injury is still unknown. To address this question, we induced liver injury in BALB/c mice with intraperitoneal injection of carbon tetrachloride with or without treatment of MaR 1. Our data showed that MaR 1 attenuated hepatic injury, oxidative stress, and lipid peroxidation induced by carbon tetrachloride, as evidenced by increased thiobarbituric acid reactive substances and reactive oxygen species levels were inhibited by treatment of MaR 1. Furthermore, MaR 1 increased activities of antioxidative mediators in carbon tetrachloride-treated mice liver. MaR 1 decreased indices of inflammatory mediators such as tumor necrosis factor-α, interleukin-6, interleukin-1β, monocyte chemotactic protein 1, myeloperoxidase, cyclooxygenase-2, and inducible nitric oxide synthase. Administration of MaR 1 inhibited activation of nuclear factor kappa B (NF-κb and mitogen-activated protein kinases (MAPKs in the liver of CCl4 treated mice. In conclusion, these results suggested the antioxidative, anti-inflammatory properties of MaR 1 in CCl4 induced liver injury. The possible mechanism is partly implicated in its abilities to inhibit ROS generation and activation of NF-κb and MAPK pathway.

The vibrational spectra of some tetrachlorides in rare gas matrices with particular reference to the molecular shapes of ThCl4 and UCl4

International Nuclear Information System (INIS)

Arthers, S.A.; Beattie, I.R.

1984-01-01

Infrared spectra of tin, lead, hafnium, thorium, and uranium tetrachlorides isolated in inert gas matrices are reported. The results obtained for the tin, lead, and hafnium compounds follow the expected isotope patterns for a tetrahedral molecule except for the observation of additional weak features to high frequency of the all- 35 Cl isotopomers. By contrast for thorium tetrachloride the observed spectrum is not characteristic of a Tsub(d) molecule but can be fitted to a species with Csub(2v) symmetry. Similar results (although less detailed) were obtained for uranium tetrachloride. (author)

Current status of the AUSTRON project

International Nuclear Information System (INIS)

Rauch, H.; Regler, M.; Lechner, R.E.; Weber, H.

2001-01-01

The current status of the AUSTRON spallation source project is described with reference to the need for neutrons in Europe and - due to a certain West-East imbalance of large research facilities - especially in Central Europe. A short overview about technical aspects of proton accelerator, rapid cycling synchrotron, storage ring, target and instrumentation is presented. (author)

Removal of Technetium, Carbon Tetrachloride, and Metals from DOE Properties - Final Report

International Nuclear Information System (INIS)

Mallouk, Thomas E.; Ponder, S.M.

2000-01-01

This research is a three year project involving close collaboration between chemists at Pennsylvania State University and materials scientists at Pacific Northwest National Laboratory (PNNL). The goal of the project is the development and characterization of supported reducing agents, and solid waste forms derived from them, which will be effective in remediation of aqueous wastes. The work follows the recent discovery that zero-valent metals, such as iron, are effective decontaminants for waste streams containing chlorinated hydrocarbons. Preliminary data, obtained at Penn State and elsewhere, have shown that the same strategy will be effective in reducing soluble compounds containing toxic metals (technetium, lead, mercury, and chromium) to insoluble forms. The Penn State group has prepared a new class of powerful reducing agents, called Ferragels, which consist of finely divided zero-valent metals on high surface area supports. Because the rate of the surface oxidation-reduction reaction depends on available surface area, Ferragels are more effective in every case tested to date than unsupported metals. The project will further develop and investigate the application of these composite materials to problems relevant to the DOE-EM mission, namely the detoxification of waste streams containing technetium, carbon tetrachloride, and toxic metal ions. The Penn State group will work closely with the PNNL group to prepare materials that are compatible with the highly corrosive liquid fraction of Hanford site tank waste, to conduct tests with waste simulants containing technetium, and to formulate and characterize vitrified waste forms derived from these materials

USE OF NARROW-DIAMETER DIRECT-PUSH WELLS TO CHARACTERIZE AND REMEDIATE CARBON TETRACHLORIDE IN THE 200 WEST AREA HANFORD SITE, WASHINGTON

International Nuclear Information System (INIS)

Rohay, V.J.

2009-01-01

This single page graphic shows several figures. The Hydraulic Hammer Rig (HHR) direct-push technology has been successfully used to characterize carbon tetrachloride in the vadose zone. Based on their favorable performance and radius of influence, HHR SVE wells have potential for future use in both monitoring and targeted SVE to achieve VOC cleanup goals at the carbon tetrachloride waste sites

Croatian repository construction project - present status and main obstacles

International Nuclear Information System (INIS)

Kucar Dragicevic, S.; Subasic, D.; Schaller, A.; Lokner, V.; Cerskov Klika, M.

1999-01-01

Croatia has been preparing backgrounds for the construction of the repository for low and intermediate radioactive waste on its territory, almost for a decade, now. In the name of Hrvtaska elektroprivreda, the co-owner of the NE Krsko, APO has been co-ordinating and organising numerous activities and projects during that time period. Siting process, safety assessment, disposal technology and repository design and public acceptance issues are the main fields of activities. The overall status of the project at the moment, including the overview of the present status of the main four aspects of activities, will be presented. Relatively, big and important progress made on the project work out during the last two years, as well as the main obstacles we were faced with during that time period, will be discussed.(author)

Reaction of carbon tetrachloride with methane in a non-equilibrium plasma at atmospheric pressure, and characterisation of the polymer thus formed

Energy Technology Data Exchange (ETDEWEB)

Gaikwad, Vaibhav [Process Safety and Environment Protection Research Group, School of Engineering, The University of Newcastle, Callaghan, NSW 2308 (Australia); Kennedy, Eric, E-mail: Eric.Kennedy@newcastle.edu.au [Process Safety and Environment Protection Research Group, School of Engineering, The University of Newcastle, Callaghan, NSW 2308 (Australia); Mackie, John [Process Safety and Environment Protection Research Group, School of Engineering, The University of Newcastle, Callaghan, NSW 2308 (Australia); Holdsworth, Clovia [Centre for Organic Electronics, Chemistry Building, School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW 2308 (Australia); Molloy, Scott; Kundu, Sazal; Stockenhuber, Michael [Process Safety and Environment Protection Research Group, School of Engineering, The University of Newcastle, Callaghan, NSW 2308 (Australia); Dlugogorski, Bogdan [School of Engineering and Information Technology, Murdoch University, Murdoch, WA 6150 (Australia)

2014-09-15

Highlights: • CCl{sub 4} remediation using non-equilibrium plasma and non-oxidative conditions is proposed. • The reaction mechanism relies on experimental data and quantum chemical analysis. • Comprehensive mass balance for the reaction is provided. • CCl{sub 4} is converted to an environmentally benign and potentially useful polymer. • Characterisation of the polymer structure based on NMR and FTIR analyses is presented. - Abstract: In this paper we focus on the development of a methodology for treatment of carbon tetrachloride utilising a non-equilibrium plasma operating at atmospheric pressure, which is not singularly aimed at destroying carbon tetrachloride but rather at converting it to a non-hazardous, potentially valuable commodity. This method encompasses the reaction of carbon tetrachloride and methane, with argon as a carrier gas, in a quartz dielectric barrier discharge reactor. The reaction is performed under non-oxidative conditions. Possible pathways for formation of major products based on experimental results and supported by quantum chemical calculations are outlined in the paper. We elucidate important parameters such as carbon tetrachloride conversion, product distribution, mass balance and characterise the chlorinated polymer formed in the process.

Correlation of NMR and refractometry to evaluate the stability constant on carbon tetrachloride

International Nuclear Information System (INIS)

Modarress, H.; Pouryazadanpanah, N.

2004-01-01

An equation has been suggested which correlate the NMR and refractometry results to evaluate the stability constant of electron donor complexes. Using this equation the stability constant of complexation between carbon tetrachloride and toluene in cyclohexane has been studied by refractometry and NMR spectroscopy

Status of LLNL granite projects

International Nuclear Information System (INIS)

Ramspott, L.D.

1980-01-01

The status of LLNL Projects dealing with nuclear waste disposal in granitic rocks is reviewed. This review covers work done subsequent to the June 1979 Workshop on Thermomechanical Modeling for a Hardrock Waste Repository and is prepared for the July 1980 Workshop on Thermomechanical-Hydrochemical Modeling for a Hardrock Waste Repository. Topics reviewed include laboratory determination of thermal, mechanical, and transport properties of rocks at conditions simulating a deep geologic repository, and field testing at the Climax granitic stock at the USDOE Nevada Test Site

Inhibitory effects of prior low-dose X-ray irradiation on carbon tetrachloride-induced hepatopathy in acatalasemic mice

International Nuclear Information System (INIS)

Yamaoka, Kiyonori; Kataoka, Takahiro; Taguchi, Takehito; Wang, Da-Hong; Mori, Shuji; Hanamoto, Katsumi; Kira, Shohei; Nomura, Takaharu

2004-01-01

The catalase activities in blood and organs of the acatalasemic (C3H/AnLCs b Cs b ) mouse of C3H strain are lower than those of the normal (C3H/AnLCs a Cs a ) mouse. We examined the effects of prior low-dose (0.5 Gy) X-ray irradiation, which reduced the oxidative damage under carbon tetrachloride-induced hepatopathy in the acatalasemic or normal mice. The acatalasemic mice showed a significantly lower catalase activity and a significantly higher glutathione peroxidase activity compared with those in the normal mice. Moreover, low-dose irradiation increased the catalase activity in the acatalasemic mouse liver to a level similar to that of the normal mouse liver. Pathological examinations and analyses of blood glutamic oxaloacetic and glutamic pyruvic transaminase activity and lipid peroxide levels showed that carbon tetrachloride induced hepatopathy was inhibited by low-dose irradiation. These findings may indicate that the free radical reaction induced by the lack of catalase and the administration of carbon tetrachloride is more properly neutralized by high glutathione peroxidase activity and low-dose irradiation in the acatalasemic mouse liver. (author)

Aviation Safety Program: Weather Accident Prevention (WxAP) Project Overview and Status

Science.gov (United States)

Nadell, Shari-Beth

2003-01-01

This paper presents a project overview and status for the Weather Accident Prevention (WxAP) aviation safety program. The topics include: 1) Weather Accident Prevention Project Background/History; 2) Project Modifications; 3) Project Accomplishments; and 4) Project's Next Steps.

European DataGrid project Status and plans

CERN Document Server

Kunszt, Peter Z

2003-01-01

The European DataGrid (EDG) project has reached, after 1.5 years, the middle of its lifetime. In this article we give an overview of the status, components, procedures and plans of the EDG project as of June 2002. The objective of the EDG project is to assist the next generation of scientific exploration, computation and analysis of large-scale data sets - from hundreds of terabytes to petabytes, across widely distributed scientific communities. The primary goal of the first phase of the EDG project was to assemble a distributed testbed to demonstrate that the EDG middleware components could be integrated into a production-quality computational Grid, as well as to gain experience with such a system. The very first version of the EDG testbed was deployed toward the end of 2001. At the first official European Union review of the project on March 1, 2002, it has been found that the project is on the right track to achieve its goals. Since then the EDG middleware, testbed components and procedures have been conti...

Status of the AFP Project in ATLAS

CERN Document Server

AUTHOR|(INSPIRE)INSPIRE-00224260; The ATLAS collaboration

2017-01-01

Status of the AFP project in the ATLAS experiment is given. In 2016 one arm of the AFP detector was installed and first data have been taken. In parallel with integration of the AFP subdetector into the ATLAS TDAQ nad DCS, beam tests and preparations for the installation of the 2nd arm are performed.

Protective Effect of the Persian Gulf brittle star Ophiocoma Erinaceus extract on carbon tetrachloride (CCl4 induced liver damage in adult male Wistar rats

Directory of Open Access Journals (Sweden)

Aida Soheili

2015-12-01

Full Text Available Background and Aim:  Brittle star possess  bioactive compounds which confer the wound healing capacity and regenerative potency of damaged  arms and organisms to this creature. The aim of the current study was to assess the   protective  effect  of  the  star extract on liver damages induced by carbon tetrachloride in adult male Wistar rats. Materials and Methods: In this experimental study, 32 adult male rats were randomly divided into 4 equal groups: control, Sham exposed, experimental 1 (treated with %25 extract and experimental 2 (treated with %50 extract of star Ophiocoma Erinaceus. The control group received no treatment. The sham exposed groups received carbon tetrachloride .(50% in olive oil .0.5 ml/kg for 7 days. The experimental groups firstly received carbon tetrachloride, then received %25, %50 brittle star extract as intragastric for 7 days. Finally, the animals were sacrificed, and their bodies and livers were weighed. Then, the livers sections were prepared and were examined by means of light microscope. Finally, the obtained  quantitative data was analyzed using SPSS (V; 20, Mini Tab software, ANOVA, and Tukey. at the significant level of P<0.001. Results: Carbon tetrachloride significantly decreased the rats’ body weight, but it increased their livers weight (P<0.001. Histopathological evaluations showed .extensive liver damage. On the other hand, treatment with brittle star extract .ncreased liver weight, reduced. body weight and significantly altered other induced changes by carbon tetrachloride on liver structure such as hepatocytes number, Kupffer cells, and arteritis, which indicated  the improvement of damaged liver tissue (P<0.001. Conclusion: It was found that brittle star extract can exert protective effects on  liver damages induced by carbon tetrachloride on male Wistar rat.

Evaluation of Hepatoprotective Effects of Hydroalcoholic Extract of Green Pepper and Parsley on the Toxicity Induced by Carbon Tetrachloride in Rats

Directory of Open Access Journals (Sweden)

E Adibfard

2014-02-01

Background & aim: Green pepper and parsley have high antioxidant properties due to flavonoids and polyphenolic compounds. The aim of this study was to investigate the hepatoprotective effects of hydroalcoholic extract of green pepper and parsley on the toxicity induced by carbon tetrachloride in rats. Methods: In the present experimental study, 48 male Wistar rats were divided into six groups of eight. The first group (negative control received olive oil, the second group receiving tetrachloride carbon and olive oil in equal proportions. The third and fourth groups (treatment groups were treated with the tetrachloride carbon and olive oil equally and then exposed to extract of parsley and green pepper to the amount of 200 mg/kg separately. The fifth and six groups were treated with tetrachloride carbon and olive oil equally, and then separately exposed to 400 mg/kg of parsley and green pepper extract. The amount of total phenol and flavonoid samples and antioxidant activities were assessed by different methods. The collected data were analyzed by One-way ANOVA tests followed by Tukey test. Results: Intraperitoneal injection of 202, 191 and 183 In.U/L of carbon tetrachloride to positive control increased the activity of alkaline phosphatase, aspartate aminotransferase and alanine aminotransferase, respectively. The injection of carbon tetrachloride increased total bilirubin at the rate of4.8 mg/dl and also decreased protein and albumin at rate of 5.1 and 2.6 g/dl.Mqdartvtal respectively 1/5 and 6/2 g, was dL ( p <0.001. In the groups treated with the extract the activity of alkaline phosphatase, aspartate aminotransferase and alanine aminotransferase in the third to sixth groups were 121, 115 and 109, 130, 121 and 121, 112 109 and 98, 118, 114, and 119 respectively. The values of bilirubin, total protein and albumin, in the III group were: 3/8, 5/5 and 2/8, Group IV: 3/9, 5/3and 2/7, the V: 3/6, 5/8 and 3/1, the VI: 3/8, 5/6 and 3, respectively. Finaly, the amount

Status Report Kuwait Nuclear Data Project

Energy Technology Data Exchange (ETDEWEB)

Farhan, A. [Kuwait Nuclear Data Center, Kuwait University, Kuwait (Kuwait)

2013-08-15

This report covers the Kuwaiti group's activities for the period April 2011 - January 2013. The Kuwait Group will continue its collaboration in order to fulfill its commitments. The Kuwait Nuclear Data Project has permanent responsibility for evaluating and updating ENSDF for A = 74 -80. The status of the mass chains is: - A = 74 (2006), - A = 75 (1999) {radical}, - A = 76 (1995) {radical}, - A = 77 (2012), - A = 78 (2009), - A = 79 (2002), - A = 80 (2005)

The LHC Project Status and Prospects

CERN Document Server

Faugeras, Paul E

2001-01-01

The Large Hadron Collider (LHC), CERN's future major facility for high-energy physics, has entered into the construction and preparation for installation phases. After recalling briefly the main machine design choices and challenges, one will review the progress of civil works for the machine and experimental areas and the status of the main LHC components, which are presently series-built and for some of them procured in kind through world-wide collaborations. Report will also be given on the full-scale prototype of an elementary LHC lattice cell, called String 2, which is being commissioned and used for optimising the installation and testing procedures of the LHC. The size and duration of the LHC Project, its intrinsic complexity and the large number of world-wide collaborations involved require rather elaborate project management tools, which will be shortly described. Finally, following the extended running of the LEP and the delay for emptying of the machine tunnel, a new planning for project completion...

Present status of the SRRC Project

International Nuclear Information System (INIS)

Chang, C.; Cheng, K.C.; Liu, Y.C.; Tseng, P.K.

1985-01-01

Upon the recommendation of the overseas Chinese scholars and the feasibility study group organized by the National Science Council, the government approved the establishment of the Synchrotron Radiation Research Center (SRRC) on July 9, 1983. The main goal of the SRRC project is to construct and operate an up-to-date 1 GeV synchrotron radiation source, with three beam lines for general experiments, in five to six years; to provide local scientists and returned scientists from abroad a facility to carry out frontier researches in both basic and applied science; and to elevate the technological capabilities of the related industries, universities, and research institutes through the construction of the machine. The background and present status of the project are discussed

Instantaneous Project Controls: Current Status, State of the Art, Benefits, and Strategies

Science.gov (United States)

Abbaszadegan, Amin

2016-01-01

Despite advancements in construction and construction-related technology, capital project performance deviations, typically overruns, remain endemic within the capital projects industry. Currently, management is generally unaware of the current status of their projects, and thus monitoring and control of projects are not achieved effectively. In…

FY-1981 project status for the Transuranic Waste Treatment Facility

International Nuclear Information System (INIS)

Benedetti, R.L.; Tait, T.D.

1981-11-01

The primary objective of the Transuranic Waste Treatment Facility (TWTF) Project is to provide a facility to process low-level transuranic waste stored at the Idaho National Engineering Laboratory (INEL) into a form acceptable for disposal at the Waste Isolation Pilot Plant. This report provides brief summary descriptions of the project objectives and background, project status through FY-1981, planned activities for FY-1982, and the EG and G TWTF Project office position on processing INEL transuranic waste

Bioavailability of andrographolide and protection against carbon tetrachloride-induced oxidative damage in rats

Energy Technology Data Exchange (ETDEWEB)

Chen, Haw-Wen [Department of Nutrition, China Medical University, Taichung, Taiwan (China); Huang, Chin-Shiu [Department of Health and Nutrition Biotechnology, Asia University, Taichung, Taiwan (China); Li, Chien-Chun [School of Nutrition, Chung Shan Medical University, Taichung, Taiwan (China); Department of Nutrition, Chung Shan Medical University Hospital, Taichung, Taiwan (China); Lin, Ai-Hsuan; Huang, Yu-Ju [Department of Nutrition, China Medical University, Taichung, Taiwan (China); Wang, Tsu-Shing [Department of Biomedical Science, Chung Shan Medical University, Taichung, Taiwan (China); Yao, Hsien-Tsung [Department of Nutrition, China Medical University, Taichung, Taiwan (China); Lii, Chong-Kuei [Department of Nutrition, China Medical University, Taichung, Taiwan (China); Department of Health and Nutrition Biotechnology, Asia University, Taichung, Taiwan (China)

2014-10-01

Andrographolide, a bioactive diterpenoid, is identified in Andrographis paniculata. In this study, we investigated the pharmacokinetics and bioavailability of andrographolide in rats and studied whether andrographolide enhances antioxidant defense in a variety of tissues and protects against carbon tetrachloride-induced oxidative damage. After a single 50-mg/kg administration, the maximum plasma concentration of andrographolide was 1 μM which peaked at 30 min. The bioavailability of andrographolide was 1.19%. In a hepatoprotection study, rats were intragastrically dosed with 30 or 50 mg/kg andrographolide for 5 consecutive days. The results showed that andrographolide up-regulated glutamate cysteine ligase (GCL) catalytic and modifier subunits, superoxide dismutase (SOD)-1, heme oxygenase (HO)-1, and glutathione (GSH) S-transferase (GST) Ya/Yb protein and mRNA expression in the liver, heart, and kidneys. The activity of SOD, GST, and GSH reductase was also increased in rats dosed with andrographolide (p < 0.05). Immunoblot analysis and EMSA revealed that andrographolide increased nuclear Nrf2 contents and Nrf2 binding to DNA, respectively. After the 5-day andrographolide treatment, one group of animals was intraperitoneally injected with carbon tetrachloride (CCl{sub 4}) at day 6. Andrographolide pretreatment suppressed CCl{sub 4}-induced plasma aminotransferase activity and hepatic lipid peroxidation (p < 0.05). These results suggest that andrographolide is quickly absorbed in the intestinal tract in rats with a bioavailability of 1.19%. Andrographolide protects against chemical-induced oxidative damage by up-regulating the gene transcription and activity of antioxidant enzymes in various tissues. - Highlights: • The bioavailability of andrographolide is 1.19% in rats. • Plasma concentration reaches 1 μM after giving 50 mg/kg andrographolide. • Andrographolide up-regulates Nrf2-dependent antioxidant genes. • Andrographolide increases antioxidant defense

Bioavailability of andrographolide and protection against carbon tetrachloride-induced oxidative damage in rats

International Nuclear Information System (INIS)

Chen, Haw-Wen; Huang, Chin-Shiu; Li, Chien-Chun; Lin, Ai-Hsuan; Huang, Yu-Ju; Wang, Tsu-Shing; Yao, Hsien-Tsung; Lii, Chong-Kuei

2014-01-01

Andrographolide, a bioactive diterpenoid, is identified in Andrographis paniculata. In this study, we investigated the pharmacokinetics and bioavailability of andrographolide in rats and studied whether andrographolide enhances antioxidant defense in a variety of tissues and protects against carbon tetrachloride-induced oxidative damage. After a single 50-mg/kg administration, the maximum plasma concentration of andrographolide was 1 μM which peaked at 30 min. The bioavailability of andrographolide was 1.19%. In a hepatoprotection study, rats were intragastrically dosed with 30 or 50 mg/kg andrographolide for 5 consecutive days. The results showed that andrographolide up-regulated glutamate cysteine ligase (GCL) catalytic and modifier subunits, superoxide dismutase (SOD)-1, heme oxygenase (HO)-1, and glutathione (GSH) S-transferase (GST) Ya/Yb protein and mRNA expression in the liver, heart, and kidneys. The activity of SOD, GST, and GSH reductase was also increased in rats dosed with andrographolide (p < 0.05). Immunoblot analysis and EMSA revealed that andrographolide increased nuclear Nrf2 contents and Nrf2 binding to DNA, respectively. After the 5-day andrographolide treatment, one group of animals was intraperitoneally injected with carbon tetrachloride (CCl 4 ) at day 6. Andrographolide pretreatment suppressed CCl 4 -induced plasma aminotransferase activity and hepatic lipid peroxidation (p < 0.05). These results suggest that andrographolide is quickly absorbed in the intestinal tract in rats with a bioavailability of 1.19%. Andrographolide protects against chemical-induced oxidative damage by up-regulating the gene transcription and activity of antioxidant enzymes in various tissues. - Highlights: • The bioavailability of andrographolide is 1.19% in rats. • Plasma concentration reaches 1 μM after giving 50 mg/kg andrographolide. • Andrographolide up-regulates Nrf2-dependent antioxidant genes. • Andrographolide increases antioxidant defense in

Graphene oxide-mediated rapid dechlorination of carbon tetrachloride by green rust

DEFF Research Database (Denmark)

Huang, Li-Zhi; Hansen, Hans Christian B.; Daasbjerg, Kim

2017-01-01

Graphene-based nanomaterials can mediate environmentally relevant abiotic redox reactions of chlorinated aliphatic hydrocarbons. In this study as low amounts as ∼0.007 % of graphene oxide (GO) was found to catalyze the reduction of carbon tetrachloride by layered Fe(II)-Fe(III) hydroxide (Green R....... This study indicates that traces of graphene oxide can affect reaction pathways as well as kinetics for dechlorination processes in anoxic sediments by facilitating a partial dechlorination....

Carbon Tetrachloride Flow Behavior in Unsaturated Hanford Caliche Material: An Investigation of Residual Nonaqueous Phase Liquids

International Nuclear Information System (INIS)

Oostrom, Mart; Lenhard, Robert J.

2003-01-01

To obtain data that can be used to study the development of a residual NAPL saturation and to test corresponding models, a detailed transient experiment was conducted in a 170-cm long by 90-cm high by 5.5-cm wide flow cell. Fluid saturation measurements were obtained with a dual-energy gamma radiation system. The experimental conditions reflected those at the Hanford Site in Washington State, where an estimated 363-580 m3 of carbon tetrachloride was disposed to the subsurface. A key subsurface feature at the Hanford Site is a sloped Plio-Pleistocene caliche layer, which was reproduced in the experiment as a sloped lens in a medium-grained, uniform, sand matrix. The caliche contains considerable amounts of calcium carbonate and may have fluid wettability properties other than strongly water wet. A total of 800 ml of carbon tetrachloride was injected in the experimental domain at a rate of 0.5 ml min-1 from a small source area located at the surface. After apparent steady-state conditions were obtained with respect to carbon tetrachloride redistribution (i.e., the formation of residual DNAPL), saturation measurements indicate that all of the DNAPL that initially moved into the caliche, remained in this layer. This experimental result could not be reproduced with numerical multifluid flow simulations based on conventional constitutive relations between relative permeability, saturation, and fluid pressures. Water was subsequently applied to the surface at a constant rate over the full length of the caliche layer to study carbon tetrachloride displacement as a result of changing water saturations. Results show that as a result of this action, 29% of the DNAPL was removed from the caliche. However, the majority of the fluid remained in the caliche entrapped by water. Simulations with the multifluid flow simulator show that the current constitutive theory for relative permeability, saturation and capillary pressure does not describe displacement physics properly

European DataGrid project: status and plans

International Nuclear Information System (INIS)

Kunszt, P.

2003-01-01

The European DataGrid (EDG) project has reached, after 1.5 years, the middle of its lifetime. In this article we give an overview of the status, components, procedures and plans of the EDG project as of June 2002. The objective of the EDG project is to assist the next generation of scientific exploration, computation and analysis of large-scale data sets--from hundreds of terabytes to petabytes, across widely distributed scientific communities. The primary goal of the first phase of the EDG project was to assemble a distributed testbed to demonstrate that the EDG middleware components could be integrated into a production-quality computational Grid, as well as to gain experience with such a system. The very first version of the EDG testbed was deployed toward the end of 2001. At the first official European Union review of the project on March 1, 2002, it has been found that the project is on the right track to achieve its goals. Since then the EDG middleware, testbed components and procedures have been continuously refined according to the requirements of our user communities and our experience

Carbon tetrachloride desorption from activated carbon

International Nuclear Information System (INIS)

Jonas, L.A.; Sansone, E.B.

1981-01-01

Carbon tetrachloride was desorbed from a granular activated carbon subsequent to its adsorption under various vapor exposure periods. The varied conditions of exposure resulted in a range of partially saturated carbon beds which, when followed by a constant flow rate for desorption, generated different forms of the desorbing concentration versus time curve. A method of analyzing the desorption curves is presented which permits extraction of the various desorbing rates from the different desorption and to relate this to the time required for such regeneration. The Wheeler desorption kinetic equation was used to calculate the pseudo first order desorption rate constant for the carbon. The desorption rate constant was found to increase monotonically with increasing saturation of the bed, permitting the calculation of the maximum desorption rate constant for the carbon at 100% saturation. The Retentivity Index of the carbon, defined as the dimensionless ratio of the adsorption to the desorption rate constant, was found to be 681

Status of the FRM-II project

International Nuclear Information System (INIS)

Boening, K.

1994-01-01

The new research reactor FRM-II at Garching near Munich is planned to become a high performance source of slow neutrons in Germany. Its design concept provides for a very compact reactor core cooled by light water and placed within a heavy water moderator tank, where a high thermal neutron flux will be obtained at only 20 MW power. - This paper begins with an overview over some of the essential design features and some more recent design modifications. It then reports on the status of the project, the most important event being a positive decision which the Bavarian State Government has made in January 1993 and which represented a green light for the project to enter the next project phase. Consequently, two official requests have been made by the Technical University of Munich, one for the nuclear licensing of the facility and the other for the so called 'Raumordnungsverfahren'. In this context the final version of the FRM-II safety report has been submitted to the nuclear licensing authority. (author)

Current status of the IREN project

International Nuclear Information System (INIS)

Furman, W.I.

1997-01-01

A current status and a corrected time-schedule of the project of the new Intense Resonance Neutron pulsed source (IREN) realized in JINR (Dubna) for experiments dealing with fundamental and applied nuclear physics studies are discussed. This source is the upgraded variant of the existing IBR-30 pulsed booster. It consists of the 200 MeV electron linac and supplying by an electron beam the photo-neutron converter placed in the center of the very fast multiplying subcritical core. The existing buildings and beam infrastructure are planned to adopt for the new IREN source. The aim of the project is to improve essentially an energy resolution of the time-of-flight spectrometer and to increase twice (up to 10 15 n/sec) an integral neutron yield. An implementation of the IREN project has started in June 1994 with the planned end in December 1997. But due to mainly insufficient financing the approved time-schedule is shifted. Now most optimistic time of start-up of the neutron source is the end of 1999

Status of the National Synchrotron Light Source project

International Nuclear Information System (INIS)

Heese, R.N.

1981-01-01

The National Synchrotron Light Source is in its final stages of construction, and as the turn-on time for the 700 MeV vuv storage ring draws near, an overview of the project is presented. Emphasis is placed on the linac and booster synchrotron performance and the status of major subsystems

Yucca Mountain Project technical status report (TSR), October 1989--March 1990

International Nuclear Information System (INIS)

1990-01-01

This Yucca Mountain Project Technical Status Report (TSR) on site characterization is the second in a series of reports that will be issued at approximately six-month intervals during site characterization. In addition, progress made toward the initiation and conduct of new site characterization activities is included. For this report, information on the technical progress made by Yucca Mountain Project participating organizations has been compiled covering the period from October 1989, through March 31, 1990. The status report consists of three sections: an introductory section; a section on the status of site characterization, which includes preparatory activities, sites programs, repository design, seals system design, waste package design, and performance assessment; and a reference section, which provides a complete listing of all published documents cited in the text. 59 refs

REDUCTIVE DEHALOGENATION OF HEXACHLOROETHANE, CARBON TETRACHLORIDE, AND BROMOFORM BY ANTHRAHYDROQUINONE DISULFONATE AND HUMIC ACID

Science.gov (United States)

The reductive dehalogenation of hexachloroethane (CzCLj), carbon tetrachloride (CC14), and bromoform (CHBr3) was examined at 50 “C in aqueous solutions containing ei- ther (1) 500 pM of 2,6-anthrahydroquinone disulfonate (AHQDS), (2) 250 pM Fe2+, or (3) 250 pM HS-. The pH ranged ...

WFIRST: Project Overview and Status

Science.gov (United States)

Kruk, Jeffrey; WFIRST Formulation Science Working Group, WFIRST Project Team

2018-01-01

The Wide-Field InfraRed Survey Telescope (WFIRST) will be the next Astrophysics flagship mission to follow JWST. The observatory payload consists of a Hubble-size telescope aperture with a wide-field NIR instrument and a coronagraph operating at visible wavelengths and employing state-of-the-art wavefront sensing and control. The Wide-field instrument is optimized for large area NIR imaging and spectroscopic surveys, with performance requirements driven by programs to study cosmology and exoplanet detection via gravitational microlensing. All data will be public immediately, and a substantial guest observer program will be supported.The WFIRST Project is presently in Phase A, with a transition to Phase B expected in early to mid 2018. Candidate observing programs are under detailed study in order to inform the mission design, but the actual science investigations will not be selected until much closer to launch. We will present an overview of the present mission design and expected performance, a summary of Project status, and plans for selecting the observing programs.

Status report : Terra Nova project environmental assessment panel : recommendations

International Nuclear Information System (INIS)

2002-01-01

An application to the Canada-Newfoundland Offshore Petroleum Board (CNOPB) was submitted by Petro-Canada on August 5, 1996, notifying of its intent to develop the petroleum resources located at the Terra Nova field. The provincial and federal governments jointly appointed the Terra Nova Project Environmental Panel, and the board of the CNOPB referred to it the application documents for review. The environmental effects, considerations of human safety incorporated into the design and operation of the Project, the general approach to the development and exploitation of the petroleum resources, and the employment and industrial benefits expected to be derived from the Project were the issues under review by the Panel. On April 22, 1997, public hearings into the review began, and the final report was submitted to governments and the Board in August 1997. The report included 75 recommendations. The Project was approved in Decision 97.02 in December 1997, and the Board dealt with each of the recommendations. The respective positions of the Governments of Canada and Newfoundland and Labrador with regard to the recommendations that fell outside the jurisdiction of the Board were made public. A status report on every one of the 75 recommendations is provided in the present report. The recommendation is repeated, the verbatim response taken from Decision 97.02 included, followed by the status of the response. The production operations phase of the Project accounts for approximately 65 per cent of the recommendations. January 20, 2002 was the date the Project was begun

Nuclear magnetic relaxation in picolines solutions in carbon tetrachloride

International Nuclear Information System (INIS)

Jurga, J.; Pajak, Z.; Jurga, K.; Jurga, S.

1973-01-01

Spin-lattice relaxation times of the ring and CH 3 group have been measured in order to establish the temperature dependence of the longitudinal relaxation times for picolins in carbon tetrachloride solutions. The information concerning the intramolecular contribution to the relaxation times have been obtained. The high resolution NPR spectrometer operating at 25 MHz has been used. The measurements have been performed in the temperature range from -60degC to 80degC. The experimental results are compared to the predictions given by the Nora Hill and Debye models and it has been found that the Nora Hill model fits the experimental data better than the Debye model. (S.B.)

Comprehensive assessment of the status scientific and technical projects using Technology Project Readiness Level

Directory of Open Access Journals (Sweden)

A. N. Petrov

2016-01-01

Full Text Available The balanced methodology for assessing the Technology Project Readiness Level for commercialization (TPRL is proposed. TPRL allows to determine the dynamics and balance of development projects that use the standardized approaches used in assessing the readiness of the technology. Validation of the methodology undertaken for the projects of Federal target programs “Research and development on priority directions of development of scientific-technological complex of Russia for 2007–2013” and “Research and development on priority directions of development of scientific-technological complex of Russia for 2014–2020”. The obtained results showed the possibility of application of the methodology for the evaluation of projects, improving efficiency of expert activity in the evaluation of projects, monitoring the status of individual project and group of projects (portfolio. The application of the methodology allowed us to improve the management of individual project and portfolio of projects.Methodology TPRL will allow the implementers, industry partners, investors, and innovative industrial companies to improve the efficiency of its activities.

Coagulation performance and floc characteristics of polytitanium tetrachloride (PTC) compared with titanium tetrachloride (TiCl4) and ferric chloride (FeCl3) in algal turbid water

KAUST Repository

Chekli, L.; Eripret, C.; Park, S.H.; Tabatabai, S. Assiyeh Alizadeh; Vronska, O.; Tamburic, B.; Kim, J.H.; Shon, H.K.

2016-01-01

Seasonal green algae blooms in freshwaters have raised attention on the need to develop novel effective treatment processes for the removal of algae in water. In the present study, the performance of newly developed polytitanium tetrachloride (PTC) coagulant for the removal of freshwater microalga Chlorella vulgaris has been investigated and compared with titanium tetrachloride (TiCl4) coagulant and the conventional ferric chloride (FeCl3) coagulant. The main benefit of using titanium-based coagulants is that the sludge produced after flocculation may be recycled into a valuable product: titanium dioxide photocatalyst. Both titanium-based coagulants achieved good flocculation over a broader pH range and coagulant dose compared to conventional FeCl3 coagulant. All three coagulants achieved comparable performance in terms of turbidity removal (i.e. turbidity removal efficiency >97%); although TiCl4 performed slightly better at the lower tested dose (i.e. <9 mg/L). Zeta potential measurements indicated that charge neutralisation may not be the sole mechanism involved in the coagulation of algae for all three coagulants. Analysis of the dynamic floc size variation during floc breakage showed no regrowth after floc breakage for the three coagulants. The flocs formed by both Ti-based coagulants were larger than those formed by FeCl3 and also grew at a faster rate. This study indicates that Ti-based coagulants are effective and promising coagulants for algae removal in water.

Coagulation performance and floc characteristics of polytitanium tetrachloride (PTC) compared with titanium tetrachloride (TiCl4) and ferric chloride (FeCl3) in algal turbid water

KAUST Repository

Chekli, L.

2016-11-11

Seasonal green algae blooms in freshwaters have raised attention on the need to develop novel effective treatment processes for the removal of algae in water. In the present study, the performance of newly developed polytitanium tetrachloride (PTC) coagulant for the removal of freshwater microalga Chlorella vulgaris has been investigated and compared with titanium tetrachloride (TiCl4) coagulant and the conventional ferric chloride (FeCl3) coagulant. The main benefit of using titanium-based coagulants is that the sludge produced after flocculation may be recycled into a valuable product: titanium dioxide photocatalyst. Both titanium-based coagulants achieved good flocculation over a broader pH range and coagulant dose compared to conventional FeCl3 coagulant. All three coagulants achieved comparable performance in terms of turbidity removal (i.e. turbidity removal efficiency >97%); although TiCl4 performed slightly better at the lower tested dose (i.e. <9 mg/L). Zeta potential measurements indicated that charge neutralisation may not be the sole mechanism involved in the coagulation of algae for all three coagulants. Analysis of the dynamic floc size variation during floc breakage showed no regrowth after floc breakage for the three coagulants. The flocs formed by both Ti-based coagulants were larger than those formed by FeCl3 and also grew at a faster rate. This study indicates that Ti-based coagulants are effective and promising coagulants for algae removal in water.

Synthesis of zirconium by zirconium tetrachloride reduction by magnesio-thermia. Experimental study and modelling; Elaboration de zirconium par reduction de tetrachlorure de zirconium par magnesothermie. Etude experimentale et modelisation

Energy Technology Data Exchange (ETDEWEB)

Basin, N

2001-01-01

This work deals with the synthesis of zirconium. The ore is carbo-chlorinated to obtain the tetrachloride which is then purified by selective condensation and extractive distillation. Zirconium tetrachloride is then reduced by magnesium and the pseudo-alloy is obtained according to the global following reaction (Kroll process): ZrCl{sub 4} + 2 Mg = 2 MgCl{sub 2}. By thermodynamics, it has been shown that the volatilization of magnesium chloride and the formation of zirconium sub-chlorides are minimized when the combined effects of temperature and of dilution with argon are limited. With these conditions, the products, essentially zirconium and magnesium chloride, are obtained in equivalence ratio in the magnesio-thermia reaction. The global kinetics of the reduction process has been studied by a thermal gravimetric method. A thermo-balance device has been developed specially for this kinetics study. It runs under a controlled atmosphere and is coupled to a vapor tetrachloride feed unit. The transformation is modelled supposing that the zirconium and magnesium chloride formation result: 1)of the evaporation of magnesium from its liquid phase 2)of the transfer of magnesium and zirconium tetrachloride vapors towards the front of the reaction located in the gaseous phase 3)of the chemical reaction. In the studied conditions, the diffusion is supposed to be the limiting process. The influence of the following parameters: geometry of the reactive zone, temperature, scanning rate of the argon-zirconium tetrachloride mixture, composition of the argon-zirconium tetrachloride mixture has been experimentally studied and confronted with success to the model. (O.M.)

The Super-B project accelerator status

CERN Document Server

Biagini, M.E.; Boni, R; Boscolo, M; Demma, T; Drago, A; Esposito, M; Guiducci, S; Marcellini, F; Mazzitelli, G; Preger, M; Raimondi, P; Sanelli, C; Serio, M; Stecchi, A; Stella, A; Tomassini, S; Zobov, M; Bertsche, K; Brachmann, A; Cai, Y; Chao, A; DeLira, A; Donald, M; Fisher, A; Kharakh, D; Krasnykh, A; Li, N; MacFarlane, D; Nosochkov, Y; Novokhatski, A; Pivi, M.; Seeman, J; Sullivan, M; Wienands, U; Weisend, J; Wittmer, W; Koop, I; Levichev, E; Nikitin, S; Piminov, P; Sinyatkin, S; Shatilov, D; Bolzon, B; Brunetti, L; Jeremie, A; Baylac, M; DeConto, J M; Gomez, Y; Meot, F; Monseu, N; Tourres, D; Bonis, J.; Chehab, R; Le Meur, G; Mercier, B; Poirier, F; Prevost, C; Rimbault, C; Touze, F; Variola, A; Chance, A; Napoly, O; Bosi, F; Liuzzo, S; Paoloni, E; Bettoni, S

2010-01-01

The SuperB project is an international effort aiming at building in Italy a very high luminosity e+e- (1036 cm-2 sec-1) asymmetric collider at the Y(4S) energy in the cm. The accelerator design has been extensively studied and changed during the past year. The present design, based on the new collision scheme, with large Piwinski angle and the use of “crab waist” sextupoles already successfully tested at the DANE -Factory at LNF Frascati, provides larger flexibility, better dynamic aperture and spin manipulation sections in the Low Energy Ring (LER) for longitudinal polarization of the electron beam at the Interaction Point (IP). The Interaction Region (IR) has been further optimized in terms of apertures and reduced backgrounds in the detector. The injector complex design has been also updated. A summary of the project status will be presented in this paper

Status of ITER Cryodistribution and Cryoline project

Science.gov (United States)

Sarkar, B.; Vaghela, H.; Shah, N.; Bhattacharya, R.; Choukekar, K.; Patel, P.; Kapoor, H.; Srinivasa, M.; Chang, H. S.; Badgujar, S.; Monneret, E.

2017-02-01

The system of ITER Cryodistribution (CD) and Cryolines (CLs) is an integral interface between the Cryoplant systems and the superconducting (SC) magnets as well as Cryopumps (CPs). The project has progressed from the conceptual stage to the industrial stage. The subsystems are at various stages of design as defined by the project, namely, preliminary design, final design and formal reviews. Significant progresses have been made in the prototypes studies and design validations, such as the CL and cold circulators. While one of the prototype CL is already tested, the other one is in manufacturing phase. Performance test of two cold circulators have been completed. Design requirements are unique due the complexity arising from load specifications, layout constraints, regulatory compliance, operating conditions as well as several hundred interfaces. The present status of the project in terms of technical achievements, implications of the changes and the technical management as well as the risk assessment and its mitigation including path forward towards realization is described.

Next Generation Life Support Project Status

Science.gov (United States)

Barta, Daniel J.; Chullen, Cinda; Pickering, Karen D.; Cox, Marlon; Towsend, Neil; Campbell, Colin; Flynn, Michael; Wheeler, Raymond

2012-01-01

Next Generation Life Support (NGLS) is one of several technology development projects sponsored by NASA s Game Changing Development Program. The NGLS Project is developing life support technologies (including water recovery and space suit life support technologies) needed for humans to live and work productively in space. NGLS has three project tasks: Variable Oxygen Regulator (VOR), Rapid Cycle Amine (RCA) swing bed, and Alternative Water Processor (AWP). The RCA swing bed and VOR tasks are directed at key technology needs for the Portable Life Support System (PLSS) for an Advanced Extravehicular Mobility Unit, with focus on test article development and integrated testing in an Advanced PLSS in cooperation with the Advanced Extra Vehicular Activity (EVA) Project. An RCA swing-bed provides integrated carbon dioxide removal and humidity control that can be regenerated in real time during an EVA. The VOR technology will significantly increase the number of pressure settings available to the space suit. Current space suit pressure regulators are limited to only two settings whereas the adjustability of the advanced regulator will be nearly continuous. The AWP effort, based on natural biological processes and membrane-based secondary treatment, will result in the development of a system capable of recycling wastewater from sources expected in future exploration missions, including hygiene and laundry water. This paper will provide a status of technology development activities and future plans.

Solvent--solvent extraction of rhodium-103m from ruthenium-103 employing a sulfate-carbon tetrachloride medium

International Nuclear Information System (INIS)

Epperson, C.E.; Landolt, R.R.; Kessler, W.V.

1976-01-01

/sup 103m/Rh in equilibrium with parent 103 Ru was separated in yields of 94 percent of those theoretically possible. 103 Ru chloride was first converted to the tetroxide which was then extracted from an aqueous solution of the equilibrium mixture with carbon tetrachloride

Vanadium purification by transformation to the tetrachloride and reduction by hydrogen. Study of the reduction mechanism

International Nuclear Information System (INIS)

Val, Christian

1968-01-01

The problem studied here is the production of very high purity metallic vanadium. By analogy with the method used for silicon or germanium production in electronics, the one employed here involves preparing the tetrachloride from the impure metal, purifying it by distillation, an easy process, and finally reducing this tetrachloride with hydrogen to obtain the pure metal. By this technique it has been possible to reduce the impurity content from about 5000 ppm to under 500 ppm and, in particular, to eliminate almost completely the nitrogen which is not removed by the normal purification methods. The author has studied the changes in the morphology of the deposit obtained as a function of the operational conditions. He has determined in particular the conditions leading to the formation of a compact deposit. He has shown that the deposition kinetics are very probably governed by an adsorbed phase reaction at the metal surface, (author) [fr

Status of the RA research reactor decommissioning project

International Nuclear Information System (INIS)

Ljubenov, V.; Nikolic, D.; Pesic, M.; Milosevic, M.; Kostic, Lj.; Steljic, M.; Sotic, O.; Antic, D. . E-mail address of corresponding author: vladan@vin.bg.ac.yu; Ljubenov, V.)

2005-01-01

The 6.5 MW heavy water RA research reactor at the VINCA Institute of Nuclear Sciences operated from 1959 to 1984. After 18 years of extended shutdown in 2002 it was decided that the reactor shutdown should be final. Preliminary decommissioning activities have been initiated by the end of 2002 under the Technical Co-operation Programme of the International Atomic Energy Agency. The objective of the project is to implement safe, timely and cost-effective decommissioning of the RA reactor up to unrestricted use of the site. Decommissioning project is closely related to two other projects: Safe Removal of the RA Reactor Spent Nuclear Fuel and Radioactive Waste Management in VINCA Institute. The main phases of the project include preparation of the detailed decommissioning plan, radiological characterization of the reactor site, dismantling and removal of the reactor components and structures, decontamination, final radiological site survey and the documentation of all the activities in order to obtain the approval for unrestricted use of the facility site. In this paper a review of the activities related to the preparation and realization of the RA reactor decommissioning project is given. Status of the project's organizational and technical aspects as for July 2004 are presented and plans for the forthcoming phases of the project realization are outlined. (author)

Current status of RCA projects and strategies for future implementation

International Nuclear Information System (INIS)

Kim, Kyoung Pyo; Lee, Jeong Kong

1998-12-01

This report is intended to provide basic overall information about ways to promote technical cooperation within the framework of RCA to accelerate and coordinate cooperative activities in nuclear science and technology in Asia and the Pacific region through a thorough review on the current status and through suggesting future implementation strategies. The contents of this report include an overall introduction of RCA, guidelines and operating rules for RCA programmes, current status and future plans for RCA projects as well as the RCA vision for the next 25 years. By reviewing the current status and future implementation strategies for RCA projects, it will help to set up a national nuclear policy aimed at seeking maximum benefits from participation in RCA projects and to implement programmes for nuclear cooperation with Asian-Pacific countries. It is expected that as a lead country for the energy sector, which is one of five thematic areas for the year 1999 - 2000 cycle programmes, Korea will continue to make significant contributions towards the implementation of RCA programmes in the future. With this report, we plan to keep up with future developments as well as implement an effective cooperation with the countries in the region so that the opinion of Korea, one of the nuclear advanced countries in the region, can be fully reflected in the establishment of future plans for RCA programmes. (author). 3 refs., 5 tabs., 1 fig

Status of the KM3NeT project

International Nuclear Information System (INIS)

Katz, U.F.

2009-01-01

KM3NeT is a future research infrastructure in the Mediterranean Sea, hosting a cubic-kilometre scale neutrino telescope and nodes for associated sciences such as marine biology, oceanology and geophysics. The status of the KM3NeT project and the progress made in the EU-funded Design Study is reviewed. Some physics studies indicating the sensitivity of the KM3NeT neutrino telescope are highlighted and selected major technical design options to be further pursued are described. Finally, the remaining steps towards construction of KM3NeT will be discussed. This document reflects the status of the KM3NeT Conceptual Design Report (CDR), which has been presented to the public for the first time at the VLVnT08 Workshop.

Status of the JET project and its supporting technological programme

International Nuclear Information System (INIS)

Bertolini, E.

1976-01-01

A brief review of the overall design of the JET facility is given. Particular JET components described include the vacuum system, toroidal field coils, poloidal system, power supplies, control and data acquisition, and status of the project towards the construction phase

Degradation Kinetics of Carbon Tetrachloride by Sulfate Green Rust as Influenced by pH and Copper Ions

Science.gov (United States)

Chlorinated solvents such as trichloroethene (TCE, C2HCl3) and carbon tetrachloride (CT, CCl4) are priority groundwater contaminants at many EPA field sites. Green rust (GR) minerals are important corrosion products of zerovalent iron (Fe0) that has been used in permeable reactiv...

Liver fibrosis in mice induced by carbon tetrachloride and its reversion by luteolin

International Nuclear Information System (INIS)

Domitrovic, Robert; Jakovac, Hrvoje; Tomac, Jelena; Sain, Ivana

2009-01-01

Hepatic fibrosis is effusive wound healing process in which excessive connective tissue builds up in the liver. Because specific treatments to stop progressive fibrosis of the liver are not available, we have investigated the effects of luteolin on carbon tetrachloride (CCl 4 )-induced hepatic fibrosis. Male Balb/C mice were treated with CCl 4 (0.4 ml/kg) intraperitoneally (i.p.), twice a week for 6 weeks. Luteolin was administered i.p. once daily for next 2 weeks, in doses of 10, 25, and 50 mg/kg of body weight. The CCl 4 control group has been observed for spontaneous reversion of fibrosis. CCl 4 -intoxication increased serum aminotransferase and alkaline phosphatase levels and disturbed hepatic antioxidative status. Most of these parameters were spontaneously normalized in the CCl 4 control group, although the progression of liver fibrosis was observed histologically. Luteolin treatment has increased hepatic matrix metalloproteinase-9 levels and metallothionein (MT) I/II expression, eliminated fibrinous deposits and restored architecture of the liver in a dose-dependent manner. Concomitantly, the expression of glial fibrillary acidic protein and α-smooth muscle actin indicated deactivation of hepatic stellate cells. Our results suggest the therapeutic effects of luteolin on CCl 4 -induced liver fibrosis by promoting extracellular matrix degradation in the fibrotic liver tissue and the strong enhancement of hepatic regenerative capability, with MTs as a critical mediator of liver regeneration.

National synchrotron light source basic design and project status

International Nuclear Information System (INIS)

van Steenbergen, A.

1981-01-01

A summary description and the basic design parameters of the National Synchrotron Light Source, a facility for the generation of intense synchrotron radiation in the vuv and x-ray range is presented, the parameters of the sources are given, the presently planned facility beam lines are tabulated and the status of the project is indicated

Next Generation Life Support Project Status

Science.gov (United States)

Barta, Daniel J.; Chullen, Cinda; Vega, Leticia; Cox, Marlon R.; Aitchison, Lindsay T.; Lange, Kevin E.; Pensinger, Stuart J.; Meyer, Caitlin E.; Flynn, Michael; Jackson, W. Andrew;

Los Alamos National Laboratory Yucca Mountain Site Characterization Project 1994 quality program status report

International Nuclear Information System (INIS)

Bolivar, S.L.

1996-03-01

This status report is for calendar year 1994. It summarizes the annual activities and accomplishments of the Los Alamos National Laboratory Yucca Mountain Site Characterization Project (YMP or Project) quality assurance program. By identifying the accomplishments of the quality program, a baseline is established that will assist in decision making, improve administrative controls and predictability, and allow us to annually identify adverse trends and to evaluate improvements. This is the fourth annual status report

Los Alamos National Laboratory Yucca Mountain Site Characterization Project 1994 quality program status report

Energy Technology Data Exchange (ETDEWEB)

Bolivar, S.L.

1996-03-01

This status report is for calendar year 1994. It summarizes the annual activities and accomplishments of the Los Alamos National Laboratory Yucca Mountain Site Characterization Project (YMP or Project) quality assurance program. By identifying the accomplishments of the quality program, a baseline is established that will assist in decision making, improve administrative controls and predictability, and allow us to annually identify adverse trends and to evaluate improvements. This is the fourth annual status report.

Study of protective effect of Avicennia marina hydroethanolic leaf extract on testes tissue and spermatogenesis in male rat induced with carbon tetrachloride

Directory of Open Access Journals (Sweden)

Z soleimani

2015-11-01

Full Text Available Aim: The toxic chemical compounds are widelyused in the world. Carbon tetrachloride which is used in hygiene industries caused tissue disorders. Medicinal plants have protective effects in body tissues. In this study the protective effect of Avicennia marina leaf extract (MLE on spermatogenesis in male rat were induced with ccl4 investigating. Method and materials: The 42 male rats with 220-250 gr body weight were divided randomly in 6 groups(n=7: control (taking normal saline,0.5ml/day, i,p , sham(taking olive oil, 0.5ml/day, i,p single dose,group induced by ccl4(carbon tetrachloride 1:1 with olive oil,0.5ml single dose, i,p, treated groups: (1,2 and3 by carbon tetrachloride 1:1 with olive oil,0.5ml single dose and 200mg/Kg, 400mg/Kg and 800mg/kg MLE /day for 96 hrs, i,p. After the examination the blood samples were collected from heart directly and testosterone , FSH, LH , sperm count, sperm motility and GSI were analyzed and the microscopic studies of testes tissue were done. All data were expressed as mean±SEM. and statistical significance differences were accepted at P<0.05. Results: Our results showed that the carbon tetrachloride has necrotic effect in testes. The number of sperm and motility were increased and microscopic study of testes tissue showed the necrosis and inflammation with decrease in spermatogonia and spermatocytes comparedwith ccl4 induced only group significantly (P<0.001 and treated groups were no changed. Conclusion: the Avicennia marina hydroethanolic extract has antioxidant and flavonoids compounds which can protect the testes tissues from toxic chemical agents.

The extraction of vanadium pentoxide from waste of titanium tetrachloride by various methods

Directory of Open Access Journals (Sweden)

Инна Михайловна Гунько

2015-04-01

Full Text Available In article the recovery possibility of vanadium pentoxide from wastes, formed as a result of purification from impurities of technical titanium tetrachloride is researched. The purification from impurities is realized by different methods – pulp of lower titanium chlorides, hydrocarbonic reducer and cascade-rectifying purification. Usage of these purification methods leads to formation of anthropogenic wastes. The researches is shown that processing of these wastes is reasonable for the purpose of vanadium pentoxide extraction

Weight Care Project: Health professionals' attitudes and ability to assess body weight status - Study protocol

LENUS (Irish Health Repository)

Moorhead, Anne

2011-03-31

Abstract Background Health professionals working in primary care and public health have opportunities to address body weight status issues with their patients through face-to-face contact. The objectives of this all-Ireland project are: 1. to assess the attitudes, current practices\\/behaviours and knowledge of key health professional groups on body weight status; 2. to assess the health professional groups\\' ability to identify body weight status in both adults and children. The health professional groups are: (a) community related public health nurses; (b) school public health nurses; (c) GPs and practice nurses (primary care); and (d) occupational health nurses (workplace) from both Northern Ireland and the Republic of Ireland. Methods\\/Design This all-Ireland multi-disciplinary project follows a mixed methods approach using both quantitative and qualitative methodologies, and consists of four components: 1. Literature review - to explore the role of health professionals in managing obesity through spontaneous intervention in a variety of health promotion settings. 2. Telephone interviews and focus groups - to gain an in-depth insight into the views of health professionals in assessing body weight status. 3. Survey (primarily online but also paper-based) - to determine the attitudes, current practices\\/behaviours and knowledge of health professionals in assessing body weight status. 4. Online evaluation study - an online interactive programme will be developed to assess health professionals\\' ability to identify the body weight status of adults and children. Discussion This project will assess and report the attitudes, current practices\\/behaviours and knowledge of key health professional groups within Northern Ireland and the Republic of Ireland on body weight status, and their ability to identify body weight status in both adults and children. The results of this project will generate recommendations for clinical practice in managing obesity, which may

Weight Care Project: Health professionals' attitudes and ability to assess body weight status - Study protocol

Directory of Open Access Journals (Sweden)

Murphy Kathy

2011-03-01

Full Text Available Abstract Background Health professionals working in primary care and public health have opportunities to address body weight status issues with their patients through face-to-face contact. The objectives of this all-Ireland project are: 1. to assess the attitudes, current practices/behaviours and knowledge of key health professional groups on body weight status; 2. to assess the health professional groups' ability to identify body weight status in both adults and children. The health professional groups are: (a community related public health nurses; (b school public health nurses; (c GPs and practice nurses (primary care; and (d occupational health nurses (workplace from both Northern Ireland and the Republic of Ireland. Methods/Design This all-Ireland multi-disciplinary project follows a mixed methods approach using both quantitative and qualitative methodologies, and consists of four components: 1. Literature review - to explore the role of health professionals in managing obesity through spontaneous intervention in a variety of health promotion settings. 2. Telephone interviews and focus groups - to gain an in-depth insight into the views of health professionals in assessing body weight status. 3. Survey (primarily online but also paper-based - to determine the attitudes, current practices/behaviours and knowledge of health professionals in assessing body weight status. 4. Online evaluation study - an online interactive programme will be developed to assess health professionals' ability to identify the body weight status of adults and children. Discussion This project will assess and report the attitudes, current practices/behaviours and knowledge of key health professional groups within Northern Ireland and the Republic of Ireland on body weight status, and their ability to identify body weight status in both adults and children. The results of this project will generate recommendations for clinical practice in managing obesity, which may

94-1 Research and development project lead laboratory support. Status report, January 1--March 31, 1997

Energy Technology Data Exchange (ETDEWEB)

Rink, N.A. [comp.

1997-08-01

This status report is published for Los Alamos National Laboratory 94-1 Research and Development Project Support. The Department of Energy Office of Environmental Management funds these projects in order to support the storage or disposal of legacy plutonium and plutonium-bearing materials that resulted from weapons production throughout the DOE complex. This report summarizes status and technical progress for Los Alamos 94-1 projects during the second quarter of fiscal year 1997.

94-1 Research and development project lead laboratory support. Status report, January 1--March 31, 1997

International Nuclear Information System (INIS)

Rink, N.A.

1997-08-01

This status report is published for Los Alamos National Laboratory 94-1 Research and Development Project Support. The Department of Energy Office of Environmental Management funds these projects in order to support the storage or disposal of legacy plutonium and plutonium-bearing materials that resulted from weapons production throughout the DOE complex. This report summarizes status and technical progress for Los Alamos 94-1 projects during the second quarter of fiscal year 1997

The CAREM project: Present status and development activities

International Nuclear Information System (INIS)

Boado Magan, H.J.; Ordonez, J.P.; Hey, A.

1997-01-01

The CAREM Project is a low power NPP of 25 Mwe, with an integrated self pressurized primary system. The cooling of the primary system is of the natural circulation type and several passive safety systems are included. The owner of the Project is Argentina's CNEA (Comision Nacional de Energia Atomica) and its associated company, INVAP, is the main contractor. The present status of the CAREM Project is presented. The possible evolution of the CAREM project is mentioned in relation with a new containment design. A short description of the Experimental Facilities, listed below, already in operation and under construction are also included: CAPCN High Pressure Loop. Natural convection loop to verify dynamic response and critical heat flux; RA-8. Critical Facility, designed and constructed for the CAREM Project (that may be used as a general uses facility); RPV lnternals. The whole assembly of absorbent rods, connecting rods and the rode guides are being constructed in a 1:1 scale. The aims of this experimental facility are vibration analysis and manufacturing parameters definitions. Control Drive Mechanisms. A series of verification and tests are being carried out on these within RPV Hydraulically driven mechanisms. Other development activities are mentioned in relation with the thermalhydraulics, Steam Generators and Control. (author)

Status of high temperature superconductor cable and fault current limiter projects at American Superconductor

International Nuclear Information System (INIS)

Maguire, J.F.; Yuan, J.

2009-01-01

This paper will describe the status of three key programs currently underway at American Superconductor Corp. The first program is the LIPA project which is a transmission voltage high temperature superconducting cable program, with funding support from the US Department of Energy. The 600 m cable, capable of carrying 574 MVA, was successfully installed and commissioned in LIPA grid on April 22, 2008. An overview of the project, system level design details and operational data will be provided. In addition, the status of the newly awarded LIPA II project will be described. The second program is Project Hydra, with funding support from the US Department of Homeland Security, to design, develop and demonstrate an HTS cable with fault current limiting functionality. The cable is 300 m long and is being designed to carry 96 MVA at a distribution level voltage of 13.8 kV. The cable will be permanently installed and energized in Manhattan, New York in 2010. The initial status of Project Hydra will be presented. The final program to be discussed is a transmission voltage, high temperature superconducting fault current limiter funded by the US DOE. The project encompasses the design, construction and test of a 115 kV FCL for power transmission within a time frame of 4-5 years. Installation and testing are planned for a Southern California Edison substation. A project overview and progress under the first phase will be reported.

Status of high temperature superconductor cable and fault current limiter projects at American Superconductor

Energy Technology Data Exchange (ETDEWEB)

Maguire, J.F., E-mail: jmaguire@amsc.co [American Superconductor Co., 64 Jackson Road, Devens, MA 01434 (United States); Yuan, J. [American Superconductor Co., 64 Jackson Road, Devens, MA 01434 (United States)

2009-10-15

This paper will describe the status of three key programs currently underway at American Superconductor Corp. The first program is the LIPA project which is a transmission voltage high temperature superconducting cable program, with funding support from the US Department of Energy. The 600 m cable, capable of carrying 574 MVA, was successfully installed and commissioned in LIPA grid on April 22, 2008. An overview of the project, system level design details and operational data will be provided. In addition, the status of the newly awarded LIPA II project will be described. The second program is Project Hydra, with funding support from the US Department of Homeland Security, to design, develop and demonstrate an HTS cable with fault current limiting functionality. The cable is 300 m long and is being designed to carry 96 MVA at a distribution level voltage of 13.8 kV. The cable will be permanently installed and energized in Manhattan, New York in 2010. The initial status of Project Hydra will be presented. The final program to be discussed is a transmission voltage, high temperature superconducting fault current limiter funded by the US DOE. The project encompasses the design, construction and test of a 115 kV FCL for power transmission within a time frame of 4-5 years. Installation and testing are planned for a Southern California Edison substation. A project overview and progress under the first phase will be reported.

Status of high temperature superconductor cable and fault current limiter projects at American Superconductor

Science.gov (United States)

Maguire, J. F.; Yuan, J.

2009-10-01

This paper will describe the status of three key programs currently underway at American Superconductor Corp. The first program is the LIPA project which is a transmission voltage high temperature superconducting cable program, with funding support from the US Department of Energy. The 600 m cable, capable of carrying 574 MVA, was successfully installed and commissioned in LIPA grid on April 22, 2008. An overview of the project, system level design details and operational data will be provided. In addition, the status of the newly awarded LIPA II project will be described. The second program is Project Hydra, with funding support from the US Department of Homeland Security, to design, develop and demonstrate an HTS cable with fault current limiting functionality. The cable is 300 m long and is being designed to carry 96 MVA at a distribution level voltage of 13.8 kV. The cable will be permanently installed and energized in Manhattan, New York in 2010. The initial status of Project Hydra will be presented. The final program to be discussed is a transmission voltage, high temperature superconducting fault current limiter funded by the US DOE. The project encompasses the design, construction and test of a 115 kV FCL for power transmission within a time frame of 4-5 years. Installation and testing are planned for a Southern California Edison substation. A project overview and progress under the first phase will be reported.

Halogeno Aldol Reaction of Ethyl Vinyl Ketone and Aldehydes Mediated by Titanium Tetrachloride

Directory of Open Access Journals (Sweden)

Guigen Li

2000-12-01

Full Text Available A three-component halogeno aldol reaction has been developed by using titanium tetrachloride as the halogen source as well as the Lewis acid mediator. The dehydration and elimination of hydrogen chloride were inhibited by conducting the reaction at 0 °C in dichloromethane or at room temperature with a shortened reaction time. Seven examples were examined, giving good to high yields (61 - 92% and modest stereoselectivity (syn/anti: 2.2/1.0 - 8.4/1.0.

Degradation Kinetics of Carbon Tetrachloride by Sulfate Green Rust as Influenced by pH and Copper Ions (Stillwater)

Science.gov (United States)

Chlorinated solvents such as trichloroethene (TCE, C2HCl3) and carbon tetrachloride (CT, CCl4) are priority groundwater contaminants at many EPA field sites. Green rust (GR) minerals are important corrosion products of zerovalent iron (Fe0) that has been used in permeable react...

Status of the McClean project, Saskatchewan, Canada

International Nuclear Information System (INIS)

Giroux, M.

1997-01-01

The paper describes the status of development of the McClean Lake uranium production project. The project includes development of a new mine/mill complex located 10 kilometres west of the Rabbit Lake mine site, in the Athabaska region of northern Saskatchewan, Canada. This first Canadian uranium project since Key Lake was developed in the late 1970s, is planned to help provide the increasing need for uranium production during the rest of the 1990s and beyond. The report describes the geological model for the 6 unconformity-type uranium orebodies named: JEB; Sue A, B and C; and McClean Lake A and B. These deposits will be extracted using both open pit and underground mines. The report describes the history of exploration and development, as well as the progression of the environmental clearance process under the joint review panel of the Canadian and Saskatchewan governments. The Canadian $250 million project, operated by Cogema Resources, is jointly owned by Denison Mines Limited, Minatco Limited and OURD (Canada) Company Limited. It is scheduled to start producing uranium concentrate in 1997. (author). 1 ref., 10 figs

The INCA project: present status and outlook

International Nuclear Information System (INIS)

Aleksandrov, K.V.; Ammosov, V.V.; Chechin, V.A.; Chubenko, A.P.; Erlykin, A.D.; Ladygin, E.A.; Merzon, G.I.; Mukhamedshin, R.A.; Murashov, V.N.; Pavlyuchenko, V.P.; Ryabov, V.A.; Ryazhskaya, O.G.; Saito, T.; Sobolevskii, N.M.; Shchepetov, A.L.; Starkov, N.I.; Trostin, I.S.; Tsarev, V.A.; Wolfendale, A.; Zatsepin, G.T.; Zhdanov, G.B.; Zhukov, A.P.

2002-01-01

Scientific objectives, foundations, status, and outlook of the INCA Project are presented. Fundamentally new technique based on the ionization-neutron calorimeter (INCA) and designed to study local nearby sources of high-energy cosmic rays by direct measuring the spectrum and composition of the nuclear component in the 'knee' region and the spectrum of primary electrons in the energy range 0.1-10 TeV with the proton-background suppression factor up to 10 7 is discussed. Experimental data on exposition of the INCA prototypes to electron, pion, and proton beams at various energies and corresponding simulation results are presented. Prospects are considered

Pulse radiolysis of porphyrin and ferriporphyrin solutions in 2-propanol-carbon tetrachloride systems. Protonation and ligand exchange kinetics

International Nuclear Information System (INIS)

Brault, D.; Neta, P.

1983-01-01

Pulse radiolysis of aqueous and nonaqueous 2-propanol-acetone-carbon tetrachloride mixtures has been investigated by means of conductivity measurements and spectrophotometry. In these solvent mixtures, a pulse of hydrochloric acid originating from either primary events of solvent radiolysis or from further reactions of carbon tetrachloride with radicals derived from 2-propanol and acetone, is produced within ca 100 nanoseconds. Further production of hydrochloric acid occurs as a result of chain reactions involving hydrogen abstraction by CCl 3 or CCl 3 O 2 radicals. These latter radicals appear to be much more reactive and are likely to be involved in the reaction unless the solutions have been thoroughly deoxygenated. Protonation Reactions of porphyrins and ferriporphyrins, which do not react rapidly with the above radicals, were followed by means of spectrophotometric measurements. In turn, these reactions may be used to monitor hydrochloric acid formation. Spectrophotometric measurements on porphyrins corroborate conductivity results, although a quantitative comparison is not feasible because of differences in solvent properties. 6 figures

The Beneficial Effect of Cape Gooseberry Juice on Carbon Tetrachloride- Induced Neuronal Damage.

Science.gov (United States)

Al-Olayan, Ebtesam M; El-Khadragy, Manal F; Omer, Sawsan A; Shata, Mohamed T M; Kassab, Rami B; Abdel Moneim, Ahmed E

2016-01-01

Cape gooseberry (Physalis peruviana L.) belongs to the Solanaceae family. Physalis has many medicinal properties however, the beneficial effect of physalis in protecting against neurotoxins has not yet been evaluated. This experimental study investigated the protective effect of physalis juice against the oxidative damage induced by carbon tetrachloride (CCl4) in the rat brain. The degrees of protection by physalis in brain tissues were evaluated by determining the brain levels of lipid peroxidation, nitric oxide, glutathione content and antioxidant enzyme activities (superoxide dismutase, catalase, glutathione-S-transferase, glutathione peroxidase and glutathione reductase), after CCl4) induction in the presence or absence of physalis. Adult male albino Wistar rats were divided into 4 groups, Group I served as the control group, Group II was intraperitoneally treated with 2 ml CCl4)/kg bwt for 12 weeks, Group III was supplemented with physalis juice via the drinking water for 12 weeks, Group IV was supplemented with physalis juice and was intraperitoneally injected weekly with CCl4). Treatment with CCl4) was significantly associated with a disturbance in the oxidative status in the brain tissues; this was marked by a significant (pphysalis along with CCl4) juice significantly (pphysalis juice supplemention inhibited apoptosis, as indicated by the increase of Bcl-2 immunoreactivity in brain tissue. Our results suggest that physalis juice could be effective in preventing neurotoxicity and the neuroprotective effect of physalis might be mediated via antioxidant and anti-apoptosis activities.

Status of the HIE-ISOLDE Project at CERN

CERN Document Server

Kadi, Y; Blumenfeld, Y; Bravin, E; Calatroni, S; Catherall, R; Fraser, M A; Goddard, B; Parchet, D; Siesling, E; Vandoni, G; Venturini Delsolaro, W; Voulot, D; Williams, L R

2012-01-01

The HIE-ISOLDE project represents a major upgrade of the ISOLDE facility with a mandate to significantly improve the quality and increase the intensity and energy of radioactive nuclear beams produced at CERN. The project will expand the experimental nuclear physics programme at ISOLDE by focusing on an upgrade of the existing REX linac with a 40 MV superconducting linac comprising thirty-two niobium-on-copper sputter-coated quarter-wave resonators housed in six cryomodules. The new linac will raise the energy of post-accelerated beams from 3 MeV/u to over 10 MeV/u. The upgrade will be staged to first deliver beam energies of 5.5 MeV/u using two high-β cryomodules placed downstream of REX, before the energy variable section of the existing linac is replaced with two low-β cryomodules and two additional high-β cryomodules are installed to attain over 10 MeV/u with full energy variability from as low as 0.45 MeV/u. An overview of the project including a status summary of the different R&D activities and ...

Transformation of carbon tetrachloride by Pseudomonas sp. strain KC under denitrification conditions

International Nuclear Information System (INIS)

Criddle, C.S.; DeWitt, J.T.; Grbic-Galic, D.; McCarty, P.L.

1990-01-01

A denitrifying Pseudomonas sp. (strain KC) capable of transforming carbon tetrachloride (CT) was isolated from groundwater aquifer solids. Major products of the transformation of 14 C-labeled CT by Pseudomonas strain KC under denitrification conditions were 14 CO 2 and an unidentified water-soluble fraction. Little or no chloroform was produced. Addition of dissolved trace metals, notably, ferrous iron and cobalt, to the growth medium appeared to enhance growth of Pseudomonas strain KC while inhibiting transformation of CT. It is hypothesized that transformation of CT by this organism is associated with the mechanism of trace-metal scavenging

Bioavailability of andrographolide and protection against carbon tetrachloride-induced oxidative damage in rats.

Science.gov (United States)

Chen, Haw-Wen; Huang, Chin-Shiu; Li, Chien-Chun; Lin, Ai-Hsuan; Huang, Yu-Ju; Wang, Tsu-Shing; Yao, Hsien-Tsung; Lii, Chong-Kuei

2014-10-01

Andrographolide, a bioactive diterpenoid, is identified in Andrographis paniculata. In this study, we investigated the pharmacokinetics and bioavailability of andrographolide in rats and studied whether andrographolide enhances antioxidant defense in a variety of tissues and protects against carbon tetrachloride-induced oxidative damage. After a single 50-mg/kg administration, the maximum plasma concentration of andrographolide was 1μM which peaked at 30min. The bioavailability of andrographolide was 1.19%. In a hepatoprotection study, rats were intragastrically dosed with 30 or 50mg/kg andrographolide for 5 consecutive days. The results showed that andrographolide up-regulated glutamate cysteine ligase (GCL) catalytic and modifier subunits, superoxide dismutase (SOD)-1, heme oxygenase (HO)-1, and glutathione (GSH) S-transferase (GST) Ya/Yb protein and mRNA expression in the liver, heart, and kidneys. The activity of SOD, GST, and GSH reductase was also increased in rats dosed with andrographolide (pandrographolide increased nuclear Nrf2 contents and Nrf2 binding to DNA, respectively. After the 5-day andrographolide treatment, one group of animals was intraperitoneally injected with carbon tetrachloride (CCl4) at day 6. Andrographolide pretreatment suppressed CCl4-induced plasma aminotransferase activity and hepatic lipid peroxidation (pandrographolide is quickly absorbed in the intestinal tract in rats with a bioavailability of 1.19%. Andrographolide protects against chemical-induced oxidative damage by up-regulating the gene transcription and activity of antioxidant enzymes in various tissues. Copyright © 2014 Elsevier Inc. All rights reserved.

Status Review of Wildlife Mitigation, Columbia Basin Hydroelectric Projects, Washington Facilities (Intrastate) Final Report.

Energy Technology Data Exchange (ETDEWEB)

Howerton, Jack

1984-11-01

This report was prepared for BPA in fulfillment of section 1004 (b)(1) of the Pacific Northwest Electric Power Planning and Conservation Act of 1980, to review the status of past, present, and proposed future wildlife planning and mitigation program at existing hydroelectric projects in the Columbia River Basin. The project evaluations will form the basis for determining any needed remedial measures or additional project analysis. Projects addressed are: Merwin Dam; Swift Project; Yale Project; Cowlitz River; Boundary Dam; Box Canyon Dam; Lake Chelan; Condit Project; Enloe Project; Spokane River; Tumwater and Dryden Dam; Yakima; and Naches Project.

Literature information applicable to the reaction of uranium oxides with chlorine to prepare uranium tetrachloride

International Nuclear Information System (INIS)

Haas, P.A.

1992-02-01

The reaction of uranium oxides and chlorine to prepare anhydrous uranium tetrachloride (UCl 4 ) are important to more economical preparation of uranium metal. The most practical reactions require carbon or carbon monoxide (CO) to give CO or carbon dioxide (CO 2 ) as waste gases. The chemistry of U-O-Cl compounds is very complex with valances of 3, 4, 5, and 6 and with stable oxychlorides. Literature was reviewed to collect thermochemical data, phase equilibrium information, and results of experimental studies. Calculations using thermodynamic data can identify the probable reactions, but the results are uncertain. All the U-O-Cl compounds have large free energies of formation and the calculations give uncertain small differences of large numbers. The phase diagram for UCl 4 -UO 2 shows a reaction to form uranium oxychloride (UOCl 2 ) that has a good solubility in molten UCl 4 . This appears more favorable to good rates of reaction than reaction of solids and gases. There is limited information on U-O-Cl salt properties. Information on the preparation of titanium, zirconium, silicon, and thorium tetrachlorides (TiCl 4 , ZrCl 4 , SiCl 4 , ThCl 4 ) by reaction of oxides with chlorine (Cl 2 ) and carbon has application to the preparation of UCl 4

Los Alamos National Laboratory Yucca Mountain Site Characterization Project 1995 quality program status report

Energy Technology Data Exchange (ETDEWEB)

Bolivar, S.L.

1996-07-01

This status report summarizes the activities and accomplishments of the Los Alamos National Laboratory Yucca Mountain Site Characterization Project`s (YMP`s) quality assurance program for January 1 to September 30, 1995. The report includes major sections on program activities and trend analysis.

Salt repository project closeout status report

International Nuclear Information System (INIS)

1988-06-01

This report provides an overview of the scope and status of the US Department of Energy (DOE's) Salt Repository Project (SRP) at the time when the project was terminated by the Nuclear Waste Policy Amendments Act of 1987. The report reviews the 10-year program of siting a geologic repository for high-level nuclear waste in rock salt formations. Its purpose is to aid persons interested in the information developed during the course of this effort. Each area is briefly described and the major items of information are noted. This report, the three salt Environmental Assessments, and the Site Characterization Plan are the suggested starting points for any search of the literature and information developed by the program participants. Prior to termination, DOE was preparing to characterize three candidate sites for the first mined geologic repository for the permanent disposal of high-level nuclear waste. The sites were in Nevada, a site in volcanic tuff; Texas, a site in bedded salt (halite); and Washington, a site in basalt. These sites, identified by the screening process described in Chapter 3, were selected from the nine potentially acceptable sites shown on Figure I-1. These sites were identified in accordance with provisions of the Nuclear Waste Policy Act of 1982. 196 refs., 21 figs., 11 tabs

An alternate metabolic hypothesis for a binary mixture of trichloroethylene and carbon tetrachloride: application of physiologically based pharmacokinetic (PBPK) modeling in rats.

Science.gov (United States)

Carbon tetrachloride (CC4) and trichloroethylene (TCE) are hepatotoxic volatile organic compounds (VOCs) and environmental contaminants. Previous physiologically based pharmacokinetic (PBPK) models describe the kinetics ofindividual chemical disposition and metabolic clearance fo...

94-1 Research and development project lead laboratory support. Status report, July 1, 1996--September 30, 1996

Energy Technology Data Exchange (ETDEWEB)

Rink, N. [comp.

1997-03-01

This document reports status and technical progress for Los Alamos 94-1 Research and Development projects. Updated schedule charts are shown in the appendix. This is the fourth status report published for Los Alamos National Laboratory 94-1 Research and Development Project Support. The Department of Energy Office of Environmental Management (DOE/EM) funds these projects in order to support the storage or disposal of legacy plutonium and plutonium-bearing materials resulting from weapons production throughout the DOE complex. This document also serves as an end-for-year review of projects and positions the program for FY97.

The technical status of the supersara project at its termination

International Nuclear Information System (INIS)

Markovina, A.; Randles, J.

1987-01-01

On March 10th 1983 the Council of Ministers of the European Community adopted the decision to abandon the SuperSARA project. In the frame of this decision, the Management of the SuperSARA project formulated the guidelines to close the project, which included the preparation of the present final report. This report presents the final status of the project, which means that it reflects the situation in March 1983, with a few updates introduced shortly afterwards in conformity with the safety requirements which were being revised at that time. The aim of this report is to give a general description of activities which were carried on to implement the experimental programme and to illustrate some important achievements reached in specific areas. In addition, it is also intended to provide the access key to the documentation which was produced in the past years, so as to make the most significant technical material easily available for any possible future use

Status of parasitism in donkeys of project and control areas in ...

African Journals Online (AJOL)

The study was undertaken with the aim of comparing the status of parasitism in donkeys in the Donkey Health and welfare Project intervention (Bereh, Ada and Boset) and Control (Yekaduda, Gerado and Meki) areas of, Central Ethiopia, in 2005. Parasites are prime problem of donkeys among other problems including ...

94-1 Research and development project lead laboratory support. Status report, January 1--March 31, 1996

International Nuclear Information System (INIS)

Dinehart, M.

1996-09-01

This document reports status and technical progress for Los Alamos National Laboratories 94-1 Research and Development projects. An introduction to the project structure and an executive summary are included. Projects described include Electrolytic Decontamination, Combustibles, Detox, Sand, Slag, and Crucible, Surveillance, and Core Technology

Los Alamos National Laboratory Yucca Mountain Site Characterization Project 1993 Quality Program status report

International Nuclear Information System (INIS)

Boliver, S.L.

1995-05-01

This status report is for calendar year 1993. It summarizes the annual activities and accomplishments of the Los Alamos National Laboratory (Los Alamos) Yucca Mountain Site Characterization Project (YMP or Project) quality assurance program. By identifying the accomplishments of the quality program, we establish a baseline that will assist in decision making, improve administrative controls and predictability, and allow us to annually identify long term trends and to evaluate improvements. This is the third annual status report (Bolivar, 1992; Bolivar, 1994). This report is divided into two primary sections: Program Activities and Trend Analysis. Under Program Activities, programmatic issues occurring in 1993 are discussed. The goals for 1993 are also listed, followed by a discussion of their status. Lastly, goals for 1994 are identified. The Trend Analysis section is a summary of 1993 quarterly trend reports and provides a good overview of the quality assurance issues of the Los Alamos YMP

Los Alamos National Laboratory Yucca Mountain Site Characterization Project 1993 Quality Program status report

Energy Technology Data Exchange (ETDEWEB)

Bolivar, S.L.

1995-05-01

This status report is for calendar year 1993. It summarizes the annual activities and accomplishments of the Los Alamos National Laboratory (Los Alamos) Yucca Mountain Site Characterization Project (YMP or Project) quality assurance program. By identifying the accomplishments of the quality program, we establish a baseline that will assist in decision making, improve administrative controls and predictability, and allow us to annually identify long term trends and to evaluate improvements. This is the third annual status report (Bolivar, 1992; Bolivar, 1994). This report is divided into two primary sections: Program Activities and Trend Analysis. Under Program Activities, programmatic issues occurring in 1993 are discussed. The goals for 1993 are also listed, followed by a discussion of their status. Lastly, goals for 1994 are identified. The Trend Analysis section is a summary of 1993 quarterly trend reports and provides a good overview of the quality assurance issues of the Los Alamos YMP.

Short status report on EFF and EAF projects

International Nuclear Information System (INIS)

Gruppelaar, H.

1991-10-01

A short status report is given on the European Fusion File (EFF) and European Activation File (EAF) projects. The EFF-2 data file is nearly finished and processing and benchmarking is underway. There is also a second version (EAF-2) of the activation file which is a very extensive and complete data base. Recently follow-up programmes have been defined for the introduction of EFF-2 to the user community after benchmarking and for further improvement of the quality of the two data files. There is extensive international cooperation, which is becoming increasingly important to solve remaining difficult problems. (author). 17 refs

Literature information applicable to the reaction of uranium oxides with chlorine to prepare uranium tetrachloride

Energy Technology Data Exchange (ETDEWEB)

Haas, P.A.

1992-02-01

The reaction of uranium oxides and chlorine to prepare anhydrous uranium tetrachloride (UCl{sub 4}) are important to more economical preparation of uranium metal. The most practical reactions require carbon or carbon monoxide (CO) to give CO or carbon dioxide (CO{sub 2}) as waste gases. The chemistry of U-O-Cl compounds is very complex with valances of 3, 4, 5, and 6 and with stable oxychlorides. Literature was reviewed to collect thermochemical data, phase equilibrium information, and results of experimental studies. Calculations using thermodynamic data can identify the probable reactions, but the results are uncertain. All the U-O-Cl compounds have large free energies of formation and the calculations give uncertain small differences of large numbers. The phase diagram for UCl{sub 4}-UO{sub 2} shows a reaction to form uranium oxychloride (UOCl{sub 2}) that has a good solubility in molten UCl{sub 4}. This appears more favorable to good rates of reaction than reaction of solids and gases. There is limited information on U-O-Cl salt properties. Information on the preparation of titanium, zirconium, silicon, and thorium tetrachlorides (TiCl{sub 4}, ZrCl{sub 4}, SiCl{sub 4}, ThCl{sub 4}) by reaction of oxides with chlorine (Cl{sub 2}) and carbon has application to the preparation of UCl{sub 4}.

Efficient dechlorination of carbon tetrachloride by hydrophobic green rust intercalated with dodecanoate anions

DEFF Research Database (Denmark)

Ayala Luis, Karina Barbara; Ginette Anneliese Cooper, Nicola; Bender Koch, Christian

2012-01-01

similar to those found in heavily contaminated groundwater close to polluted industrial sites (14 988 mu M) was reduced mainly to the fully dechlorinated products carbon monoxide (CO, yields >54 and formic acid (HCOOH, yields >6. Minor formation of chloroform (CF), the only chlorinated degradation product......The reductive dechlorination of carbon tetrachloride (CT) by Fe-II-Fe-III hydroxide (green rust) intercalated with dodecanoate, (Fe4Fe2III)-Fe-II (OH)(12)(C12H23O2)(2)center dot gamma H2O (designated GR(C12)), at pH similar to 8 and at room temperature was investigated. CT at concentration levels...

Outbreak of carbon tetrachloride poisoning in a color printing factory related to the use of isopropyl alcohol and an air conditioning system in Taiwan.

Science.gov (United States)

Deng, J F; Wang, J D; Shih, T S; Lan, F L

1987-01-01

Three workers from a color printing factory were admitted to community hospitals in 1985 with manifestations of acute hepatitis. One of the three had superimposed acute renal failure and pulmonary edema. An investigation was subsequently conducted at the plant to determine the etiology of the outbreak and the prevalence of liver disease among the remaining workers. Comprehensive medical evaluations were conducted, which included physical examinations, liver function tests, and serological screening for hepatitis. Seventeen of 25 workers from the plant had abnormal liver function tests 10 days after the outbreak, and a significant association was found between the presence of abnormal liver function tests and a history of recently having worked inside any of three rooms in which an interconnecting air conditioning system had been installed to cool the printing machines. After further investigation, it was determined that the incident occurred following inadvertent use of carbon tetrachloride to clean a pump in the printing machine. A simulation of the pump cleaning operation revealed ambient air levels of carbon tetrachloride of 300-500 ppm. Ultimately, it was concluded that the outbreak was in all likelihood due to the combined use of carbon tetrachloride and isopropyl alcohol in the cleaning operation. This outbreak underscores the importance of adopting appropriate industrial hygiene measures in a rapidly industrializing nation such as Taiwan.

Amino acid assisted dehalogenation of carbon tetrachloride by green rust

DEFF Research Database (Denmark)

Yin, Weizhao; Strobel, Bjarne W.; Hansen, Hans Chr. Bruun

2017-01-01

that reduce the formation of toxic by-products such as chloroform (CF). In this study, carbon tetrachloride (CT) dehalogenation by the chloride form of GR (GRCl) was tested in presence of glycine (GLY) and other selected amino acids. GLY, alanine (ALA) or serine (SER) all resulted in remarkable suppression...... of CF formation with only ~ 10% of CF recovery while sarcosine (SAR) showed insignificant effects. For two non-amino acid buffers, TRIS had little effect while HEPES resulted in a 40 times lower rate constant compared to experiments where no buffer was added. The FeII complexing properties of the amino...... acids and buffers caused variable extents of GRCl dissolution which was linearly correlated with CF suppression and dehalogenation rate. We hypothesize that the CF suppression seen for amino acids is caused by stabilization of carbene intermediates via the carbonyl group. Different effects on CF...

Effect of Apitherapy Formulations against Carbon Tetrachloride-Induced Toxicity in Wistar Rats after Three Weeks of Treatment

Directory of Open Access Journals (Sweden)

Calin Vasile Andritoiu

2014-08-01

Full Text Available The human body is exposed nowadays to increasing attacks by toxic compounds in polluted air, industrially processed foods, alcohol and drug consumption that increase liver toxicity, leading to more and more severe cases of hepatic disorders. The present paper aims to evaluate the influence of the apitherapy diet in Wistar rats with carbon tetrachloride-induced hepatotoxicity, by analyzing the biochemical determinations (enzymatic, lipid and protein profiles, coagulation parameters, minerals, blood count parameters, bilirubin levels and histopathological changes at the level of liver, spleen and pancreas. The experiment was carried out on six groups of male Wistar rats. Hepatic lesions were induced by intraperitoneal injection of carbon tetrachloride (dissolved in paraffin oil, 10% solution. Two mL per 100 g were administered, every 2 days, for 2 weeks. Hepatoprotection was achieved with two apitherapy diet formulations containing honey, pollen, propolis, Apilarnil, with/without royal jelly. Biochemical results reveal that the two apitherapy diet formulations have a positive effect on improving the enzymatic, lipid, and protein profiles, coagulation, mineral and blood count parameters and bilirubin levels. The histopathological results demonstrate the benefits of the two apitherapy diet formulations on reducing toxicity at the level of liver, spleen and pancreas in laboratory animals.

Status Review of Wildlife Mitigation, Columbia Basin Hydroelectric Projects, Columbia River Mainstem Facilities, 1984 Final Report.

Energy Technology Data Exchange (ETDEWEB)

Howerton, Jack; Hwang, Diana

1984-11-01

This report reviews the status of past, present, and proposed future wildlife planning and mitigation programs at existing hydroelectric projects in the Columbia River Basin. The project evaluations will form the basis for determining any needed remedial measures or additional project analysis. Each hydropower facility report is abstracted separately for inclusion in the Energy Data Base.

[Study on of the current status of volatile organic compounds pollution in typical rural drinking water and the relationship between its concentration and health of the population, in Huai'an, Jiangsu].

Science.gov (United States)

Pan, Enchun; Zhang, Qin; Yang, Fangying; Hu, Wei; Xu, Qiujin; Liang, Cunzhen; He, Yuan; Wang, Chuang

2014-10-01

This study was to understand the status of pollution on drinking water, by volatile organic compounds (VOCs), among rural residents living in the basin of Huaihe River. Relationship between the morbidity, morbidity of cancers and VOCs were also explored. 28 villages were chosen from Xuyi,Jinhu, Chuzhou along the Huaihe River, with water samples collected from ditch pond water, shallow wells, deep wells in November-December 2010. VOCs indicators were evaluated according to the Standard Quality GB 5749-2006 for Drinking Water. Methylene chloride, chloroform, benzene and carbon tetrachloride were all detected in 76 water samples. The rates of chloroform, benzene, carbon tetrachloride which exceeding the quality standards were 3.95% , 21.05% and 22.37% , but no significant differences were found among these three water resources in chloroform, benzene or carbon tetrachloride. Results from the correlation analysis showed that benzene had positive correlation with tumor deaths (r = 0.24, P water resources (P > 0.05). Drinking waters for rural residents along the Huaihe River were polluted while VOCs might have related to tumor incidence with potential impact and risk to the health of local residents.

Actual status of project Mochovce NPP units 3 and 4 completion

International Nuclear Information System (INIS)

Niznan, S.

2005-01-01

In this presentation author deals with actual status of project Mochovce NPP units 3 and 4 completion. Present state of Mochovce NPP, Units 3 and 4 enables real assumption to completion. It is expected that such supplier companies can be used which are experienced in field of nuclear projects. Based on budget of 2002, it seems that completion costs of 45 billions SKK are real. These figures were confirmed by study performed by TRACTEBEL in 2004. Based on experience from Bohunice NPP completion as well as from Mochovce NPP, Units 1 and 2 completion and if decision milestone and project start up deadlines will be observed according to modified preliminary schedule of Mochovce NPP Units 3 and 4 completion, it seems as real that Unit 3 will be completed till 06/2011 and Unit 4 - till 12/2011.

Biological effects of pesticides on rats treated with carbon tetrachloride

International Nuclear Information System (INIS)

Abdel Kader, S.M.

1990-01-01

The present study investigates the effect of repeated oral doses of the organophosphorus pesticide, cytrolane on normal and pretreated rate with different oral doses of carbon tetrachloride. For that purpose the effect of cytrolane, CCl 4 and their potential interaction had been studied on brain and erythrocyte acetylcholinesterase (Ache), plasma cholinesterase (Ch E), liver succinic dehydrogenase (SDH), serum alkaline phosphatase (SAP), liver succinic dehydrogenas (SDH), serum alkaline phosphatase (SAP), glutamic oxaloacetic (GOT) and glutamic pyruvic (GPT) transaminases. It also investigates the effect of an acute oral dose of cytrolane at short time intervals (1/2-24 hours) on brain and blood ache of normal and pretreated rate with a single oral dose of CCl 4 . The distribution and excretion of 1 4cc1 4 at different time intervals (2,6 and 24 hours) in normal rats and in rats pretreated with o.89 mg cytrolane/kg/day for a week had been determined in different organs, expired air, urine and faeces

Current sources of carbon tetrachloride (CCl4) in our atmosphere

Science.gov (United States)

Sherry, David; McCulloch, Archie; Liang, Qing; Reimann, Stefan; Newman, Paul A.

2018-02-01

Carbon tetrachloride (CCl4 or CTC) is an ozone-depleting substance whose emissive uses are controlled and practically banned by the Montreal Protocol (MP). Nevertheless, previous work estimated ongoing emissions of 35 Gg year-1 of CCl4 into the atmosphere from observation-based methods, in stark contrast to emissions estimates of 3 (0-8) Gg year-1 from reported numbers to UNEP under the MP. Here we combine information on sources from industrial production processes and legacy emissions from contaminated sites to provide an updated bottom-up estimate on current CTC global emissions of 15-25 Gg year-1. We now propose 13 Gg year-1 of global emissions from unreported non-feedstock emissions from chloromethane and perchloroethylene plants as the most significant CCl4 source. Additionally, 2 Gg year-1 are estimated as fugitive emissions from the usage of CTC as feedstock and possibly up to 10 Gg year-1 from legacy emissions and chlor-alkali plants.

The PEP-II Project: Low-Energy Ring Design and Project Status

International Nuclear Information System (INIS)

Zisman, Michael S.

2006-01-01

We describe the present status of the PEP-II project. The project comprises four major systems: Injector, High-Energy Ring (HER), Low-Energy Ring (LER), and Interaction Region (IR). We focus in detail on the design of the LER, as its parameters and requirements are most closely related to those required for the Beijing Tau-Charm Factory rings. The PEP-II LER is a high-current, 3.1-GeV positron ring mounted above the 9-GeV HER. The LER uses a wiggler located in one of its six straight sections to provide emittance control and additional damping. We describe the rather complicated IR, which must transport the LER beam into the plane of the HER, focus it to a common beam size, and separate the beams after the head-on collisions. Both permanent magnet and conventional electromagnets are used in this area. The LER lattice has now adopted a simplified non-interleaved sextupole correction scheme that has reduced the required number of sextupoles substantially. We describe the LER vacuum system, one of the most challenging subsystems in PEP-II. It employs several technologies. In the arcs, aluminum extrusions and titanium sublimation pumps are employed; the straight sections use stainless steel chambers with lumped ion pumps. In the wiggler area, an extended copper photon dump with nonevaporable getter (NEG) pumps is employed to handle the very large synchrotron radiation power. The design of the room-temperature RF system, the bunch-by-bunch longitudinal and transverse feedback systems, and some of the special diagnostics will be described briefly. The PEP-II project remains on schedule to begin commissioning of the HER in April 1997, followed by the LER a year later

Status of SPIRAL. The radioactive beam project at GANIL

International Nuclear Information System (INIS)

Lieuvin, M.

1995-01-01

SPIRAL, a radioactive ion beam facility (RIB) is under construction at GANIL (Caen, France). The heavy ion beams of GANIL will be used to produce radioactive atoms by the ISOL method. After ionisation by an ECR ion source (ECRIS), the low energy radioactive beam is axially injected on the first orbit of a k=265 compact cyclotron. The final energy will range between 1.7 and 25 MeV/u (harmonics 5 to 2) and the accelerated ions will be sent to the existing GANIL experimental areas. The present status of the project is described. (author)

CURRENT STATUS OF RESEARCH PROJECT ACTIVITIES IN MEDICAL UNIVERSITIES IN BULGARIA.

Directory of Open Access Journals (Sweden)

Svetoslav Garov

2013-07-01

Full Text Available Introduction: In Bulgaria there are five medical universities: in the cities of Sofia, Plovdiv, Varna, Pleven and Stara Zagora. Their main mission is training specialists in the fields of medicine and health care, increasing their qualification by means of postgraduate education and performing research activities. One of medical universities’ top priorities is encouraging research activities mainly aimed at preparation and implementation of research projects. Aim: The purpose of our study is to examine the current status of research project activities in Bulgarian medical universities.Material and methods: In order to define the science competitions related to Bulgarian medical universities we have applied a documentary and sociological approach. Results: Research projects that Bulgarian medical universities can apply for are divided into two groups – national and international. The most significant international projects are European ones since Bulgaria is an EU member state and this allows us to participate in such projects. Conclusion: Universities should strive for establishing even better conditions for encouraging application for research projects aimed at developing competent and experienced staff, even though the majority of them may not obtain approval for financing.The changes in the situation regarding Bulgarian science require the implementation and development of more research staff motivated to improve their knowledge and skills in the relevant dynamically changing competition and project field.

2. status colloquium of the project 'Applied ecology' (PAOe). Proceedings

International Nuclear Information System (INIS)

Breitenstein, A.; Scholz, W.; Waitzmann, M.; Zelesny, H.

1994-01-01

The 'Applied ecology' programme sponsors research on major subjects concerning application-oriented bases of nature conservation and environmental protection in the following sectors: 1. nature and landscape (succession research, scientific accompanying of measures restoring the natural condition of a landscape, nature conservation concepts and development of ecological paradigms); 2. ecotoxicology (further development and standardization of biological indication methods within the framework of the ecotoxicological register of effects of Baden-Wuertemberg, design of exposure models for forcasting long-term changes in Baden-Wuertemberg); 3. risk assessments and risk evaluations in environmental protection (selected ecological balances and development of ecological evaluation criteria).- On March 22nd and 23rd, 1994, the second status colloquium of the project ''Applied Ecology (PAOe)'' was held at Ettlingen. During this annual event, the results of 39 research projects in the above-mentioned major subject areas were presented and debated by 600 experts from science, administration and economy. This volume sums up the results of the research and demonstrates, at the same time, the range of the research projects sponsored under this scheme. (orig./VHE) [de

New capacity and the status of major projects

International Nuclear Information System (INIS)

Osborne, R.; Eastman, P.; Bajc, F.; Hawthorne, D.

2003-01-01

This session included highlights from from four guest speakers who were asked to comment on new electricity capacity in Ontario and the status of major projects. The summer of 2002 was one of the hottest on record in Ontario and presented a challenge for suppliers of electricity to meet demand. Some of the extra demand was met by interties. Imports provided 5 per cent of consumption in July and 8 per cent in August. TransAlta and ATCO are currently involved in 2 major projects to add generation capacity. In addition, Ontario Power Generation is getting more production from its existing nuclear plants and has made significant investment to get greater efficiency and increase safety margins at the plants. One panelist suggested that nuclear power is a key part of meeting Canada's Kyoto greenhouse reduction obligations. It was emphasized that market participants should allow time to let the market work and let a free market respond to price signals. It was argued that consumers expect and rely too much on low-cost electricity and are therefore not encouraged to conserve energy or look into new generation requirements. figs

The workings of a molecular thermometer: the vibrational excitation of carbon tetrachloride by a solvent.

Science.gov (United States)

Graham, Polly B; Matus, Kira J M; Stratt, Richard M

2004-09-15

An intriguing energy-transfer experiment was recently carried out in methanol/carbon tetrachloride solutions. It turned out to be possible to watch vibrational energy accumulating in three of carbon tetrachloride's modes following initial excitation of O-H and C-H stretches in methanol, in effect making those CCl(4) modes "molecular thermometers" reporting on methanol's relaxation. In this paper, we use the example of a CCl(4) molecule dissolved in liquid argon to examine, on a microscopic level, just how this kind of thermal activation occurs in liquid solutions. The fact that even the lowest CCl(4) mode has a relatively high frequency compared to the intermolecular vibrational band of the solvent means that the only solute-solvent dynamics relevant to the vibrational energy transfer will be extraordinarily local, so much so that it is only the force between the instantaneously most prominent Cl and solvent atoms that will significantly contribute to the vibrational friction. We use this observation, within the context of a classical instantaneous-pair Landau-Teller calculation, to show that energy flows into CCl(4) primarily via one component of the nominally degenerate, lowest frequency, E mode and does so fast enough to make CCl(4) an excellent choice for monitoring methanol relaxation. Remarkably, within this theory, the different symmetries and appearances of the different CCl(4) modes have little bearing on how well they take up energy from their surroundings--it is only how high their vibrational frequencies are relative to the solvent intermolecular vibrational band edge that substantially favors one mode over another.

Assessment of the Mutagenic Potential of Carbon Disulfide, Carbon Tetrachloride, Dichloromethane, Ethylene Dichloride, and Methyl Bromide: A Comparative Analysis in Relation to Ethylene Dibromide

Science.gov (United States)

The document provides an evaluation of the mutagenic potential of five alternative fumigants to ethylene dibromide(EDB). These include carbon disulfide(CS2), carbon tetrachloride(CCl4), dichloromethane(DCM), ethylene dichloride(EDC), and methyl bromide (MB). Of the five proposed ...

Hepatoprotective effects of setarud against carbon tetrachloride-induced liver injury in rats.

Science.gov (United States)

Khorshid, Hamid Reza Khorram; Azonov, Jahan A; Novitsky, Yury A; Farzamfar, Bardia; Shahhosseiny, Mohammad Hassan

2008-01-01

To assess the hepatoprotective activity of a new herbal drug "setarud" in experimental liver fibrosis, 48 male Wistar rats were divided into four groups: controls, carbon tetrachloride (CCl4) group, and two treatment groups that received CCl4 and setarud at doses of 0.02 or 0.04 g/Kg/day for 30 days. Body weight gain, biochemical liver tests, bile flow rate and composition, and changes in liver morphology in the four groups were studied. CCl4 administration led to morphological and biochemical evidence of liver injury as compared to untreated controls. Setarud administration led to significant protection against CCl4-induced changes in body weight gain, liver morphology, bile flow and concentration. It was also associated with significantly lower serum liver enzyme levels (pliver disease are warranted.

Western Gas Sands Project. Status report, 1 June--30 June 1979

Energy Technology Data Exchange (ETDEWEB)

1979-01-01

This edition of the WGSP status report summarizes June 1979 progress of government-sponsored projects directed toward increasing gas production from the low-permeability gas sands of the western United States. Background information is provided in the September 1977, status report, NVO/0655-100. Work by the USGS toward resource assessment in the four primary study areas continued. CK GeoEnergy started a core hole in Grand County, Utah. During June, projects of the National Laboratories and Energy Technology Centers continued. Bartlesville Energy Technology Center continued work on fracture conductivity, rock-fluid interaction, and log evaluation and interpretation techniques. Experimental and theoretical work on hydraulic fracturing mechanics and analysis of well test data continued at Lawrence Livermore Laboratory. The CER Corporation RB-MHF 3 final report has been distributed. Cyclic gas injection began again on CIG's Sprague No. 1 well. The DOE well test facility was transported to Vernal, Utah for minor repairs and storage. The GPE wells, Natural Buttes Units 9, 14 and 18 flowed to sales. The Mitchell Energy Muse-Duke No. 1 well flowed 3,000 MCFD in June. Attempts to kill the Mobil PCU F31-13G well failed. Exploratory coring of the Sandia Hole No. 6 Formation Interface Fracture Experiment resumed in June.

Orientation correlation and intermolecular structure of GeCl4, VCl4 and other tetrachloride liquids

International Nuclear Information System (INIS)

Nath, P.P.; Sarkar, S.; Joarder, R.N.

2007-01-01

The intermolecular structure and correlation of GeCl 4 , VCl 4 and other tetrachloride liquids can be well described by Misawa's orientation correlation model originally applied to liquid CCl 4 . The model supports on average a specific 'corner' to 'face' correlation, but evidently very different from 'Apollo' type model. The Misawa model appears to work, in some respect, even better than reference interaction site model (RISM) used for long to describe intermolecular structure of such molecular systems. The test and comparison are made through the calculation of small asymmetric part of the intermolecular structure and evaluation of partial atom-atom distribution functions

Tampa Electric Company Polk Power Station IGCC project: Project status

Energy Technology Data Exchange (ETDEWEB)

McDaniel, J.E.; Carlson, M.R.; Hurd, R.; Pless, D.E.; Grant, M.D. [Tampa Electric Co., FL (United States)

1997-12-31

The Tampa Electric Company Polk Power Station is a nominal 250 MW (net) Integrated Gasification Combined Cycle (IGCC) power plant located to the southeast of Tampa, Florida in Polk County, Florida. This project is being partially funded under the Department of Energy`s Clean Coal Technology Program pursuant to a Round II award. The Polk Power Station uses oxygen-blown, entrained-flow IGCC technology licensed from Texaco Development Corporation to demonstrate significant reductions of SO{sub 2} and NO{sub x} emissions when compared to existing and future conventional coal-fired power plants. In addition, this project demonstrates the technical feasibility of commercial scale IGCC and Hot Gas Clean Up (HGCU) technology. The Polk Power Station achieved ``first fire`` of the gasification system on schedule in mid-July, 1996. Since that time, significant advances have occurred in the operation of the entire IGCC train. This paper addresses the operating experiences which occurred in the start-up and shakedown phase of the plant. Also, with the plant being declared in commercial operation as of September 30, 1996, the paper discusses the challenges encountered in the early phases of commercial operation. Finally, the future plans for improving the reliability and efficiency of the Unit in the first quarter of 1997 and beyond, as well as plans for future alternate fuel test burns, are detailed. The presentation features an up-to-the-minute update on actual performance parameters achieved by the Polk Power Station. These parameters include overall Unit capacity, heat rate, and availability. In addition, the current status of the start-up activities for the HGCU portion of the plant is discussed.

Los Alamos National Laboratory Yucca Mountain Site Characterization Project 1995 quality program status report

International Nuclear Information System (INIS)

Bolivar, S.L.

1996-07-01

This status report summarizes the activities and accomplishments of the Los Alamos National Laboratory Yucca Mountain Site Characterization Project's (YMP's) quality assurance program for January 1 to September 30, 1995. The report includes major sections on program activities and trend analysis

Process and operating device for an apparatus using a running liquid film and application to separation of Zr and Hf tetrachlorides

International Nuclear Information System (INIS)

Brun, R.

1989-01-01

A process is claimed allowing to maintain a thin film in a running film exchanger, by increasing the flow rate for a short time to establish a film all over the surface. Application is made to continuous condensation of zirconium and hafnium tetrachlorides, from the separation column, by absorption in a liquid solvent made of potassium chloroaluminate [fr

Implementation status of the extreme light infrastructure - nuclear physics (ELI-NP) project

Energy Technology Data Exchange (ETDEWEB)

Gales, S., E-mail: sydney.gales@eli-np.ro; Zamfir, N. V., E-mail: sydney.gales@eli-np.ro [ELI-NP, Horia Hulubei National Institute for Physics and Nuclear Engineering, 30 Reactorului Street, RO-077125 Bucharest-Magurele (Romania)

2015-02-24

The Project Extreme Light Infrastructure (ELI) is part of the European Strategic Forum for Research Infrastructures (ESFRI) Roadmap. ELI will be built as a network of three complementary pillars at the frontier of laser technologies. The ELI-NP pillar (NP for Nuclear Physics) is under construction near Bucharest (Romania) and will develop a scientific program using two 10 PW lasers and a Compton back-scattering high-brilliance and intense gamma beam, a marriage of laser and accelerator technology at the frontier of knowledge. In the present paper, the technical description of the facility, the present status of the project as well as the science, applications and future perspectives will be discussed.

Los Alamos National Laboratory Yucca Mountain Site Characterization Project: 1991 quality program status report

International Nuclear Information System (INIS)

1992-07-01

This status report summarizes the activities and accomplishments of the Los Alamos National Laboratory (Los Alamos) Yucca Mountain Site Characterization Project's (YMP) quality assurance program for calendar year 1991. The report is divided into three Sections: Program Activities, Verification Activities, and Trend Analysis

Hepatoprotective Effect of Trigona spp. Bee Propolis against Carbon Tetrachloride-Induced Liver Injury in Rat

Directory of Open Access Journals (Sweden)

Rachel Amelia

2016-06-01

Full Text Available Background: Oxidative stress reaction can cause liver injury. This process can be prevented by antioxidant activities which can break the destructive chain caused by free radical substances in the liver. Propolis produced by Trigona spp. bee is known to have a high level of antioxidant. The aim of this study was to examine the effect of Trigona spp. bee propolis on liver histological toxicity caused by carbon tetrachloride-induced oxidative stress. Methods:This experimental study was conducted in September 2013 at the Animal Laboratory of Departement of Pharmacology and Therapy, Faculty of Medicine Universitas Padjadjaran. Twenty-four healthy male Wistar rats as objects were adapted for one week and randomly divided into 3 groups. Group I was the control negative, group II was given carbon tetrachloride on day 14, group III was given Trigona spp. bee propolis on day 1-14. On day 14, group III was injected CCl4 intraperitoneally. The quantitative data were statistically analyzed using the one way ANOVA and Tukey test with p value < 0.05. Results: Group I showed the liver contained normal cells, without significant injury of the membrane, round and complete nucleus. The average number of liver cell was 464 ± 9.59281 cells/field; group II underwent necrosis and the average of the cells was 146 ± 7.56885 cells/field; group III showed some normal liver cells, and some necrotic area with the normal liver cells average was 263 ± 14.10860 cells/field. The p-value=0.00. Conclusions: Trigona spp. bee propolis has a hepatoprotective effect against CCl4-induced liver injury histologically.

FAIR - Facility, Research Program and Status of the Project

International Nuclear Information System (INIS)

Majka, Z.

2011-01-01

The international Facility for Antiproton and Ion Research (FAIR) in Europe will provide a worldwide science community with a unique and technically innovative accelerator system to perform forefront research in the sciences concerned with the basic structure of matter, and in intersections with other fields. The facility will deliver an extensive range of primary and secondary particle beams from protons and their antimatter partners, antiprotons, to ion beams of all chemical elements up to the heaviest, uranium, with in many respects unique properties and intensities. The paper will include overview of the new facility design and research programs to be carried out there. The current status of the FAIR project will be also presented. (author)

Simultaneous biodegradation of carbon tetrachloride and trichloroethylene in a coupled anaerobic/aerobic biobarrier

Energy Technology Data Exchange (ETDEWEB)

Kwon, Kiwook [Department of Civil and Environmental Engineering, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan, Gyeonggi-do 15588 (Korea, Republic of); Shim, Hojae [Department of Civil and Environmental Engineering, Faculty of Science and Technology, University of Macau, Macau SAR, 999078 (China); Bae, Wookeun, E-mail: wkbae@hanyang.ac.kr [Department of Civil and Environmental Engineering, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan, Gyeonggi-do 15588 (Korea, Republic of); Oh, Juhyun; Bae, Jisu [Department of Civil and Environmental Engineering, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan, Gyeonggi-do 15588 (Korea, Republic of)

2016-08-05

Highlights: • Coupled biodegradation of carbon tetrachloride (CT) and trichloroethylene (TCE) in biobarrier with polyethylene glycol carriers. • TCE aerobically cometabolized and CT anaerobically dechlorinated. • Removal efficiencies of over 98%, leaving residuals below or near the regulatory standards. • Coupled aerobic/anaerobic environments established by H{sub 2}O{sub 2} injected at 50% of electron donor. • Longer retention time (from 3.6 to 7.2 days) achieved satisfactory removal at lower temperature (18 °C). - Abstract: Simultaneous biodegradation of carbon tetrachloride (CT) and trichloroethylene (TCE) in a biobarrier with polyethylene glycol (PEG) carriers was studied. Toluene/methanol and hydrogen peroxide (H{sub 2}O{sub 2}) were used as electron donors and an electron acceptor source, respectively, in order to develop a biologically active zone. The average removal efficiencies for TCE and toluene were over 99.3%, leaving the respective residual concentrations of ∼12 and ∼57 μg/L, which are below or close to the groundwater quality standards. The removal efficiency for CT was ∼98.1%, with its residual concentration (65.8 μg/L) slightly over the standards. TCE was aerobically cometabolized with toluene as substrate while CT was anaerobically dechlorinated in the presence of electron donors, with the respective stoichiometric amount of chloride released. The oxygen supply at equivalent to 50% chemical oxygen demand of the injected electron donors supported successful toluene oxidation and also allowed local anaerobic environments for CT reduction. The originally augmented (immobilized in PEG carriers) aerobic microbes were gradually outcompeted in obtaining substrate and oxygen. Instead, newly developed biofilms originated from indigenous microbes in soil adapted to the coupled anaerobic/aerobic environment in the carrier for the simultaneous and almost complete removal of CT, TCE, and toluene. The declined removal rates when temperature

Status of spallation neutron source program in High Intensity Proton Accelerator Project

International Nuclear Information System (INIS)

Oyama, Yukio

2001-01-01

Japan Atomic Energy Research Institute and High Energy Accelerator Organization are jointly designing a 1 MW spallation neutron source as one of the research facilities planned in the High Intensity Proton Accelerator Project. The spallation neutron source is driven by 3 GeV proton beam with a mercury target and liquid hydrogen moderators. The present status of design for these spallation source and relevant facility is overviewed. (author)

Present status of spallation target development. JAERI/KEK Joint Project

International Nuclear Information System (INIS)

Hino, R.; Kaminaga, M.; Haga, K.

2001-01-01

The Japan Atomic Energy Research Institute (JAERI) and the High Energy Accelerator Research Organization (KEK) are promoting a plan to construct a neutron scattering facility under the JAERI/KEK Joint Project. Design and R and D works are being carried out vigorously for realizing the mercury target system consisting of the mercury target, moderators and reflectors working as a spallation neutron source, as well as a remote handling system for exchanging such components which will be highly irradiated. This report introduces an outline of the present status of design and development activities on the spallation target system. (author)

National Status and Trends, Benthic Surveillance Project Sites, 1984-1992, National Centers for Coastal Ocean Science

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set reports information regarding the nominal sampling locations for the National Status and Trends Benthic Surveillance Project sites. One record is...

Comparison of imatinib, nilotinib and silymarin in the treatment of carbon tetrachloride-induced hepatic oxidative stress, injury and fibrosis

OpenAIRE

Shaker, Mohamed E.; Zalata, Khaled R.; Mehal, Wajahat Z.; Shiha, Gamal E.; Ibrahim, Tarek M.

2011-01-01

Effective and well-tolerated anti-fibrotic drugs are currently lacking. Therefore, this study was carried out to investigate the potential anti-fibrotic effects of imatinib, nilotinib and silymarin on established hepatic fibrosis in the carbon tetrachloride (CCl4) rat model. Male Wistar rats received intraperitoneal injections of CCl4 twice weekly for 8 weeks, as well as daily intraperitoneal treatments of imatinib (10 and 20 mg/kg), nilotinib (10 and 20 mg/kg) and silymarin (100 mg/kg) durin...

Status of Radon Related Activities in Member States Participating in Technical Cooperation Projects in Europe

International Nuclear Information System (INIS)

2017-03-01

This publication summarizes the status of radon programmes at the start of 2014 in the Member States in Europe participating in the IAEA technical cooperation project on establishing enhanced approaches to the control of public exposure to radon. The current status was determined from responses to a questionnaire covering the following elements of a national radon action plan: policies and strategies; radon measurement surveys; establishment of reference levels; managing radon in existing buildings and in future buildings; education and training of professionals; and public awareness initiatives.

Supplementation of Citrus maxima Peel Powder Prevented Oxidative Stress, Fibrosis, and Hepatic Damage in Carbon Tetrachloride (CCl4) Treated Rats.

Science.gov (United States)

Chowdhury, Mohammed Riaz Hasan; Sagor, Md Abu Taher; Tabassum, Nabila; Potol, Md Abdullah; Hossain, Hemayet; Alam, Md Ashraful

2015-01-01

Citrus maxima peel is rich in natural phenolic compounds and has a long use in the traditional medicine. HPLC-DAD analysis on Citrus maxima peel powder exhibited the presence of various phenolic compounds such as caffeic acid and (-)-epicatechin. To determine the plausible hepatoprotective activity of Citrus maxima peel powder, we used carbon tetrachloride (CCl4) treated rat model. Liver damage in rats was confirmed by measuring the AST, ALT, and ALP enzyme activities. In addition, lipid peroxidation products (MDA), nitric oxide, advanced protein oxidation products level (APOP), and catalase activities were also analyzed along with the histological profiling for the inflammatory cell infiltration, collagen, and iron deposition in liver. Dietary supplementation of Citrus maxima peel powder exhibited significant reduction of serum AST, ALT, and ALP activities in carbon tetrachloride treated rats. Moreover, Citrus maxima peel powder also showed a significant reduction of the oxidative stress markers (MDA, NO, and APOP level) and restored the catalase activity in CCl4 treated rats. Histological examination of the liver section revealed reduced inflammatory cells infiltration, collagen, and iron deposition in CCl4 treated rats. The results from this study demonstrated that Citrus maxima peel powder produced significant hepatoprotective action in CCl4 administered rats.

Supplementation of Citrus maxima Peel Powder Prevented Oxidative Stress, Fibrosis, and Hepatic Damage in Carbon Tetrachloride (CCl4 Treated Rats

Directory of Open Access Journals (Sweden)

Mohammed Riaz Hasan Chowdhury

2015-01-01

Full Text Available Citrus maxima peel is rich in natural phenolic compounds and has a long use in the traditional medicine. HPLC-DAD analysis on Citrus maxima peel powder exhibited the presence of various phenolic compounds such as caffeic acid and (−-epicatechin. To determine the plausible hepatoprotective activity of Citrus maxima peel powder, we used carbon tetrachloride (CCl4 treated rat model. Liver damage in rats was confirmed by measuring the AST, ALT, and ALP enzyme activities. In addition, lipid peroxidation products (MDA, nitric oxide, advanced protein oxidation products level (APOP, and catalase activities were also analyzed along with the histological profiling for the inflammatory cell infiltration, collagen, and iron deposition in liver. Dietary supplementation of Citrus maxima peel powder exhibited significant reduction of serum AST, ALT, and ALP activities in carbon tetrachloride treated rats. Moreover, Citrus maxima peel powder also showed a significant reduction of the oxidative stress markers (MDA, NO, and APOP level and restored the catalase activity in CCl4 treated rats. Histological examination of the liver section revealed reduced inflammatory cells infiltration, collagen, and iron deposition in CCl4 treated rats. The results from this study demonstrated that Citrus maxima peel powder produced significant hepatoprotective action in CCl4 administered rats.

Implementing and operating the Hanford Environmental Information System and applying it to the carbon tetrachloride expedited response action

International Nuclear Information System (INIS)

Cowley, P.J.; Last, G.V.; Schwab, M.R.; Rohay, V.J.

1993-02-01

To manage waste and perform environmental monitoring and restoration at the 1450-square kilometer (560-square mile) Hanford Site in southeastern Washington State, vast amounts of scientific and technical data are being generated from sampling. This paper provides an overview of the Hanford Environmental Information System (HEIS), a computerized system designed and implemented to manage the Site's environmental sampling data, lessons learned from putting HEIS into operation, and how HEIS is being applied to the carbon tetrachloride expedited response action being performed at the Site

Protective effects of pomegranate (Punica granatum) juice on testes against carbon tetrachloride intoxication in rats

Science.gov (United States)

2014-01-01

Background Pomegranate fruit has been extensively used as a natural medicine in many cultures. The present study was aimed at evaluating the protective effects of pomegranate (Punica granatum) juice against carbon tetrachloride (CCl4)-induced oxidative stress and testes injury in adult Wistar rats. Methods Twenty eight Wistar albino male rats were divided equally into 4 groups for the assessment of protective potential of pomegranate juice. Rats of group I (control) received only vehicles and had free access to food and water. Rats of groups II and IV were treated with CCl4 (2 ml/kg bwt) via the intraperitoneal route once a week for ten weeks. The pomegranate juice was supplemented via drinking water 2 weeks before and concurrent with CCl4 treatment to group IV. Group III was supplemented with pomegranate juice for twelve weeks. The protective effects of pomegranate on serum sex hormones, oxidative markers, activities of antioxidant enzymes and histopathology of testes were determined in CCl4-induced reproductive toxicity in rats. Results Pomegranate juice showed significant elevation in testosterone, luteinizing hormone (LH) and follicle stimulating hormone (FSH) those depleted by the injection of CCl4. Activity levels of endogenous testesticular antioxidant enzymes; superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione-S-transferase (GST) and glutathione reductase (GR) and glutathione (GSH) contents were increased while lipid peroxidation (LPO) and nitric oxide (NO) were decreased with pomegranate juice. Moreover, degeneration of germ and Leydig cells along with deformities in spermatogenesis induced after CCl4 injections were restored with the treatment of pomegranate juice. Conclusion The results clearly demonstrated that pomegranate juice augments the antioxidant defense mechanism against carbon tetrachloride-induced reproductive toxicity and provides evidence that it may have a therapeutic role in free radical mediated

Protective effects of pomegranate (Punica granatum) juice on testes against carbon tetrachloride intoxication in rats.

Science.gov (United States)

Al-Olayan, Ebtesam M; El-Khadragy, Manal F; Metwally, Dina M; Abdel Moneim, Ahmed E

2014-05-22

Pomegranate fruit has been extensively used as a natural medicine in many cultures. The present study was aimed at evaluating the protective effects of pomegranate (Punica granatum) juice against carbon tetrachloride (CCl4)-induced oxidative stress and testes injury in adult Wistar rats. Twenty eight Wistar albino male rats were divided equally into 4 groups for the assessment of protective potential of pomegranate juice. Rats of group I (control) received only vehicles and had free access to food and water. Rats of groups II and IV were treated with CCl4 (2 ml/kg bwt) via the intraperitoneal route once a week for ten weeks. The pomegranate juice was supplemented via drinking water 2 weeks before and concurrent with CCl4 treatment to group IV. Group III was supplemented with pomegranate juice for twelve weeks. The protective effects of pomegranate on serum sex hormones, oxidative markers, activities of antioxidant enzymes and histopathology of testes were determined in CCl4-induced reproductive toxicity in rats. Pomegranate juice showed significant elevation in testosterone, luteinizing hormone (LH) and follicle stimulating hormone (FSH) those depleted by the injection of CCl4. Activity levels of endogenous testesticular antioxidant enzymes; superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione-S-transferase (GST) and glutathione reductase (GR) and glutathione (GSH) contents were increased while lipid peroxidation (LPO) and nitric oxide (NO) were decreased with pomegranate juice. Moreover, degeneration of germ and Leydig cells along with deformities in spermatogenesis induced after CCl4 injections were restored with the treatment of pomegranate juice. The results clearly demonstrated that pomegranate juice augments the antioxidant defense mechanism against carbon tetrachloride-induced reproductive toxicity and provides evidence that it may have a therapeutic role in free radical mediated diseases.

Tri-State Synfuels Project Review: Volume 12. Fluor project status. [Proposed Henderson, Kentucky coal to gasoline plant; engineering

Energy Technology Data Exchange (ETDEWEB)

1982-06-01

The purpose of this report is to document and summarize activities associated with Fluor's efforts on the Tri-State Synfuels Project. The proposed facility was to be coal-to-transport fuels facility located in Henderson, Kentucky. Tri-State Synfuels Company was participating in the project as a partner of the US Department of Energy per terms of a Cooperative Agreement resulting from DOE's synfuel's program solicitation. Fluor's initial work plan called for preliminary engineering and procurement services to the point of commitment for construction for a Sasol Fischer-Tropsch plant. Work proceeded as planned until October 1981 when results of alternative coal-to-methanol studies revealed the economic disadvantage of the Synthol design for US markets. A number of alternative process studies followed to determine the best process configuration. In January 1982 Tri-State officially announced a change from Synthol to a Methanol to Gasoline (MTG) design basis. Further evaluation and cost estimates for the MTG facility eventually led to the conclusion that, given the depressed economic outlook for alternative fuels development, the project should be terminated. Official announcement of cancellation was made on April 13, 1982. At the time of project cancellation, Fluor had completed significant portions of the preliminary engineering effort. Included in this report are descriptions and summaries of Fluor's work during this project. In addition location of key project data and materials is identified and status reports for each operation are presented.

SiC/SiC fuel cladding R and D Project 'SCARLET': Status and future plan

International Nuclear Information System (INIS)

Kishimoto, Hirotatsu; Kohyama, Akira

2015-01-01

This paper provides the recent progress in SiC/SiC development towards early utilisation for LWRs based on NITE method. After the March 11 Disaster in East-Japan, ensuring safe technology for LWR became a top priority R and D in nuclear energy policy of Japan. Along this line, replacement of Zircaloy claddings with SiC/SiC based fuel cladding is becoming one of the most attractive options and a MEXT fund based project, SCARLET, and a METI fund based project have been launched as 5-year termed projects at Muroran Institute of Technology. These projects care for NITE process for making long SiC/SiC fuel pins and connecting technology integration. The SCARLET project also includes coolant compatibility and irradiation effect evaluations as LWR and LMFBR materials. The outline and the present status of the SCARLET project will be briefly introduced in the present paper. (authors)

Status of the Fermilab Energy Doubler/Saver project

Energy Technology Data Exchange (ETDEWEB)

1977-01-01

The possibility of building a ring of superconducting magnets was considered very early in the design of the Fermilab main accelerator. It was concluded that the technology of superconducting magnets was not at that time, sufficiently advanced. Therefore, the main ring was designed and built with conventional magnets. However, space was left in the main-ring tunnel for a future ring of superconducting magnets. The Energy Doubler/Saver (ED/S) was initiated in 1972 as a project to build a ring of superconducting magnets with the objective of dramatically increasing the research potential of the Fermilab accelerators. This was to be accomplished at a moderate cost and in such a manner as to make possible a significant saving of electrical energy. A description is given of the evolution of this program as well as give a status report of the Ed/S research and development program.

Status of the Fermilab Energy Doubler/Saver project

International Nuclear Information System (INIS)

1977-01-01

The possibility of building a ring of superconducting magnets was considered very early in the design of the Fermilab main accelerator. It was concluded that the technology of superconducting magnets was not at that time, sufficiently advanced. Therefore, the main ring was designed and built with conventional magnets. However, space was left in the main-ring tunnel for a future ring of superconducting magnets. The Energy Doubler/Saver (ED/S) was initiated in 1972 as a project to build a ring of superconducting magnets with the objective of dramatically increasing the research potential of the Fermilab accelerators. This was to be accomplished at a moderate cost and in such a manner as to make possible a significant saving of electrical energy. A description is given of the evolution of this program as well as give a status report of the Ed/S research and development program

Socioeconomic Status As a Risk Factor for Unintended Pregnancy in the Contraceptive CHOICE Project.

Science.gov (United States)

Iseyemi, Abigail; Zhao, Qiuhong; McNicholas, Colleen; Peipert, Jeffrey F

2017-09-01

To evaluate the association of low socioeconomic status as an independent risk factor for unintended pregnancy. We performed a secondary analysis of data from the Contraceptive CHOICE project. Between 2007 and 2011, 9,256 participants were recruited and followed for up to 3 years. The primary outcome of interest was unintended pregnancy; the primary exposure variable was low socioeconomic status, defined as self-report of either receiving public assistance or having difficulty paying for basic necessities. Four contraceptive groups were evaluated: 1) long-acting reversible contraceptive method (hormonal or copper intrauterine device or subdermal implant); 2) depot medroxyprogesterone acetate injection; 3) oral contraceptive pills, a transdermal patch, or a vaginal ring; or 4) other or no method. Confounders were adjusted for in the multivariable Cox proportional hazard model to estimate the effect of socioeconomic status on risk of unintended pregnancy. Participants with low socioeconomic status experienced 515 unintended pregnancies during 14,001 women-years of follow-up (3.68/100 women-years; 95% CI 3.37-4.01) compared with 200 unintended pregnancies during 10,296 women-years (1.94/100 women-years; 95% CI 1.68-2.23) among participants without low socioeconomic status. Women with low socioeconomic status were more likely to have an unintended pregnancy (unadjusted hazard ratio [HR] 1.8, 95% CI 1.5-2.2). After adjusting for age, education level, insurance status, and history of unintended pregnancy, low socioeconomic status was associated with an increased risk of unintended pregnancy (adjusted HR 1.4, 95% CI 1.1-1.7). Despite the removal of cost barriers, low socioeconomic status is associated with a higher incidence of unintended pregnancy.

ISTIMES project: status and outcomes

Science.gov (United States)

Cuomo, V.; Proto, M.; Soldovieri, F.

2012-04-01

ISTIMES is a project approved in the Seventh Framework Programme of the European Union under the Joint Call FP7-ICT-SEC-2007-1. It has a three years duration and will be completed within June 2012. According to the aims of the proposal, ISTIMES project has designed, assessed and developed a prototypical modular and scalable ICT-based system, exploiting distributed and local sensors, for non-destructive electromagnetic monitoring; the specific application field was the reliability and safety of critical transport infrastructures, even if the modularity of the ISTIMES approach has permitted to extend it successfully to other critical infrastructures as dams. The continuous and fruitful involvement of end users (as Italian Civil Protection) allowed to develop applications focused on users needs. ISTIMES couples current monitoring of infrastructures with a high situational awareness during crises management, providing updated and detailed real and near real time information about the infrastructure status to improve decision support for emergency and disasters stakeholders. The system exploits an open network architecture that can accommodate a wide range of heterogeneous sensors, static and mobile, and can be easily scaled up to allow the integration of additional sensors and interfaces with other networks. It relies on state-of-the-art electromagnetic sensors, enabling a networking of terrestrial sensors, supported by specific satellite and airborne measurements. The integration of electromagnetic technologies with new ICT information and telecommunications systems enables remotely controlled monitoring and surveillance at different temporal and spatial scales, providing indexes and images of the critical transport infrastructures. The project has exploited, assessed and improved many different non-invasive technologies based on electromagnetic sensing as: Optic Fiber Sensors, Synthetic Aperture; Radar (SAR) satellite platform; Hyperspectral Spectroscopy; Infrared

Status Review of Wildlife Mitigation at 14 of 27 Major Hydroelectric Projects in Idaho, 1983-1984 Final Report.

Energy Technology Data Exchange (ETDEWEB)

Martin, Robert C.; Mehrhoff, L.A.

1985-01-01

The Pacific Northwest Electric Power Planning and Conservation Act and wildlife and their habitats in the Columbia River Basin and to compliance with the Program, the wildlife mitigation status reports coordination with resource agencies and Indian Tribes. developed the Columbia River Basin Fish and Wildlife Program development, operation, and maintenance of hydroelectric projects on existing agreements; and past, current, and proposed wildlife factual review and documentation of existing information on wildlife meet the requirements of Measure 1004(b)(l) of the Program. The mitigation, enhancement, and protection activities were considered. In mitigate for the losses to those resources resulting from the purpose of these wildlife mitigation status reports is to provide a resources at some of the Columbia River Basin hydroelectric projects the river and its tributaries. To accomplish this goal, the Council were written with the cooperation of project operators, and in within Idaho.

Current Status of the LOFAR EoR Key Science Project

Science.gov (United States)

Koopmans, L. V. E.; LOFAR EoR KSP Team

2018-05-01

A short status update on the LOFAR Epoch of Reionization (EoR) Key Science Project (KSP) is given, regarding data acquisition, data processing and analysis, and current power-spectrum limits on the redshifted 21-cm signal of neutral hydrogen at redshifts z = 8 - 10. With caution, we present a preliminary astrophysical analysis of ~60 hr of processed LOFAR data and their resulting power spectrum, showing that potentially already interesting limits on X-ray heating during the Cosmic Dawn can already be gained. This is by no means the final analysis of this sub-set of data, but illustrates the future potential when all nearly 3000 hr of data in hand on two EoR windows will have been processed.

94-1 Research and Development Project Lead Laboratory Support. Status report, April 1, 1996--June 30, 1996

Energy Technology Data Exchange (ETDEWEB)

Dinehart, M. [comp.

1996-10-01

This document reports status and technical progress for Los Alamos 94-1 Research and Development projects concerned with the management of plutonium and plutonium contaminated materials during the third quarter of FY96.

National Status and Trends, Benthic Surveillance Project Chemistry Data, 1984-1992, National Centers for Coastal Ocean Science

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The National Status and Trends (NS&T) Benthic Surveillance Project Chemistry data file reports the trace concentrations of a suite of chemical contaminants in...

National Status and Trends, Benthic Surveillance Project Chemistry Data, 1984-1992, National Centers for Coastal Ocean Science

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The National Status and Trends (NSandT) Benthic Surveillance Project Chemistry data file reports the trace concentrations of a suite of chemical contaminants in...

Compliance status summaries for federal and state statutory directives that apply to the Salt Repository Project at the Deaf Smith County Site, Texas

International Nuclear Information System (INIS)

1986-07-01

This document contains statutory summaries, checklists of compliance requirements, status summaries, and lists of information needs for the environmental and health and safety statutory directives at Federal and State levels that apply to the Salt Repository Project at the Deaf Smith County Site, Texas. Statutes that apply in general to any repository project but not specifically to the Deaf Smith are not included. The information herein supplements the Salt Repository Project Statutory Compliance Plan and the Salt Repository Project Permitting Management Plan by providing lengthy details on statutory directives, compliance requirements, information needs, and the overall status of the environmental and health and safety compliance program for the Salt Repository Project at the Deaf Smith County Site, Texas

Antihepatotoxic effect of golden berry (Physalis peruviana Linn.) in carbon tetrachloride (CCl4) intoxicated rats.

Science.gov (United States)

Taj, Darakhshan; Khan, Hira; Sultana, Viqar; Ara, Jehan; Ehteshamul-Haque, Syed

2014-05-01

Liver is the main site in the body for intense metabolism and excretion. A number of chemicals and drugs which are used routinely cause liver damage. The present study investigates the antihepatotoxic effect of Physalis peruviana whole ripe fruit, water and ethanol extracts of fruit in normal as well as in carbon tetrachloride (CCl(4)) intoxicated rats. The CCl(4) treated rats showed marked elevation in liver enzymes: alanine transaminse, aspratate transaminase, alkaline phosphatase, lactate dehydrogenase and other biochemical parameters: bilirubin, creatinine and urea, thus indicating liver injury. Whereas animal treated/fed with various preparations of Physalis peruviana showed significant lowering effect (pPhysalis peruviana showed highest activity in both rat models while ripe fruit and ethanol extract showed moderate activity compared to standard drug.

The SuperB Project: Status and the Physics Reach

International Nuclear Information System (INIS)

Neri, Nicola

2012-01-01

The SuperB experiment is a next generation Super Flavour Factory expected to accumulate 75 ab −1 of data at the Υ(4S) in five years of nominal running, and will be built at the recently established Cabibbo Laboratory on the outskirts of Rome. In addition to running data at the Υ(4S), SuperB will be able to accumulate data from the ψ(3770) up to the Υ(6S). A polarized electron beam enables unique physics opportunities at SuperB. The large samples of B, D and τ decays that will be recorded at SuperB can be used to provide both stringent constraints on new physics scenarios, and over-constraints on the Standard Model. We present the status of the project as well as the physics potential of SuperB.

Status of the R+D programme in the field of the heat carrying and heat transfer components of the PNP project

International Nuclear Information System (INIS)

Mausbeck, H.; Jansing, W.

1984-01-01

The PNP Project (Project Nuclear Process Heat) is described. It covers the status of research and development in the field of heat exchange and heat exchanger components; concept of plant for coal gasification; description of large scale test facilities and its components; and the time schedule for the project development

Development of a Process for a High Capacity Arc Heater Production of Silicon for Solar Arrays

Science.gov (United States)

Reed, W. H.

1979-01-01

A program was established to develop a high temperature silicon production process using existing electric arc heater technology. Silicon tetrachloride and a reductant (sodium) are injected into an arc heated mixture of hydrogen and argon. Under these high temperature conditions, a very rapid reaction is expected to occur and proceed essentially to completion, yielding silicon and gaseous sodium chloride. Techniques for high temperature separation and collection were developed. Included in this report are: test system preparation; testing; injection techniques; kinetics; reaction demonstration; conclusions; and the project status.

Proceedings of the symposium on the joint research project between JAERI and Universities. Status and perspective of the advanced radiation technology project

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-06-01

This report describes the Proceedings of the Symposium on the Joint Research Project between JAERI and Universities -Status and Perspective of the Advanced Radiation Technology Project-, held at Tokyo on January 27, 1999. After a series of conferences which had been held at the second or third year to present the main activities of this unique collaborative project system, the symposium was particularly focused on critical reviewing of the project and on its future. The scientific papers presented were the recent achievements in the themes: 1) nuclear spectroscopy and nuclear materials science with an isotope separator on-line; 2) radiation shielding and nuclear data for use of accelerators; 3) materials analysis methods using ion beams; 4) microstructure in polymer materials irradiated with ions; 5) effects of transmutation products in fusion-reactor materials; 6) physiological study of plants using positron-emitting isotopes. The new theme titled 'Development and application of micro PIXE analysis in the atmospheric pressure' was proposed. Eight panelists discussed the future of the project. The 17 papers are indexed individually. (J.P.N.)

76 FR 76153 - Notice of Effectiveness of Exempt Wholesale Generator Status; Caney River Wind Project, LLC...

Science.gov (United States)

2011-12-06

...] Notice of Effectiveness of Exempt Wholesale Generator Status; Caney River Wind Project, LLC, Mesquite Solar 1, LLC, Copper Crossing Solar LLC, Copper Mountain Solar 1, LLC, Pinnacle Wind, LLC, Bellevue... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket Nos. EG11-115-000, EG11-116-000...

Structure and energetics of clusters relevant to thorium tetrachloride melts

International Nuclear Information System (INIS)

Akdeniz, Z.; Tosi, M.P.

2000-08-01

We study within an ionic model the structure and the energetics of neutral and charged clusters which may exist as structural units in molten ThCl 4 and in its liquid mixtures with alkali chlorides, with reference to Raman scattering experiments by Photiadis and Papatheodorou. As stressed by these authors, the most striking facts for ThCl 4 in comparison with other tetrachlorides (and in particular with ZrCl 4 ) are the appreciable ionic conductivity of the pure melt and the continuous structural changes which occur in the melt mixtures with varying composition. After adjusting our model to data on the isolated ThCl 4 tetrahedral molecule, we evaluate (i) the Th 2 Cl 8 dimer and the singly charged species obtained by chlorine-ion transfer between two such neutral dimers; (ii) the ThCl 6 and ThCl 7 clusters both as charged anions and as alkali -compensated species; and (iii) various oligomers carrying positive or negative double charges. Our study shows that the characteristic structural properties of the ThCl 4 compound and of the alkali-Th chloride systems are the consequence of the relatively high ionic character of the binding, which is already evident in the isolated ThCl 4 molecular monomer. (author)

Design of an Extractive Distillation Column for the Environmentally Benign Separation of Zirconium and Hafnium Tetrachloride for Nuclear Power Reactor Applications

Directory of Open Access Journals (Sweden)

Le Quang Minh

2015-09-01

Full Text Available Nuclear power with strengthened safety regulations continues to be used as an important resource in the world for managing atmospheric greenhouse gases and associated climate change. This study examined the environmentally benign separation of zirconium tetrachloride (ZrCl4 and hafnium tetrachloride (HfCl4 for nuclear power reactor applications through extractive distillation using a NaCl-KCl molten salt mixture. The vapor–liquid equilibrium behavior of ZrCl4 and HfCl4 over the molten salt system was correlated with Raoult’s law. The molten salt-based extractive distillation column was designed optimally using a rigorous commercial simulator for the feasible separation of ZrCl4 and HfCl4. The molten salt-based extractive distillation approach has many potential advantages for the commercial separation of ZrCl4 and HfCl4 compared to the conventional distillation because of its milder temperatures and pressure conditions, smaller number of required separation trays in the column, and lower energy requirement for separation, while still taking the advantage of environmentally benign feature by distillation. A heat-pump-assisted configuration was also explored to improve the energy efficiency of the extractive distillation process. The proposed enhanced configuration reduced the energy requirement drastically. Extractive distillation can be a promising option competing with the existing extraction-based separation process for zirconium purification for nuclear power reactor applications.

Fasting ameliorates metabolism, immunity, and oxidative stress in carbon tetrachloride-intoxicated rats.

Science.gov (United States)

Sadek, Km; Saleh, Ea

2014-12-01

Fasting has been recently discovered to improve overall health, but its beneficial effects in the presence of hepatic insufficiency have not been proven. The influence of fasting on the metabolism, immunological aspects, and oxidative stress of 40 male carbon tetrachloride (CCl4)-intoxicated Wistar rats was investigated in the present study. The rats were divided into four groups, including a placebo group, CCl4-intoxicated rats, which were injected subcutaneously with 1.0 ml/kg of CCl4 solution, a fasting group, which was fasted 12 h/day for 30 days, and a fourth group, which was injected with CCl4 and fasted. The metabolism, immunity, and oxidative stress improved in CCl4-intoxicated rats fasted for 12 h/day for 30 days, as evidenced in significant increase (p fasting improved metabolism, immunity, and oxidative stress in CCl4-intoxicated rats. Thus, fasting during Ramadan is safe for patients with hepatic disorders, as the prophet Mohammed (S) said "Keep the fast, keep your health". © The Author(s) 2014.

Present status and future directions of the Mayo/IBM PACS project

Science.gov (United States)

Morin, Richard L.; Forbes, Glenn S.; Gehring, Dale G.; Salutz, James R.; Pavlicek, William

1991-07-01

This joint project began in 1988 and was motivated by the need to develop an alternative to the archival process in place at that time (magnetic tape) for magnetic resonance imaging and neurological computed tomography. In addition, this project was felt to be an important step in gaining the necessary clinical experience for the future implementation of various aspects of electronic imaging. The initial phase of the project was conceived and developed to prove the concept, test the fundamental components, and produce performance measurements for future work. The key functions of this phase centered on attachment of imaging equipment (GE Signa) and archival processes using a non-dedicated (institutionally supplied) local area network (LAN). Attachment of imaging equipment to the LAN was performed using commercially available devices (Ethernet, PS/2, Token Ring). Image data were converted to ACR/NEMA format with retention of the vendor specific header information. Performance measurements were encouraging and led to the design of following projects. The second phase has recently been concluded. The major features of this phase have been to greatly expand the network, put the network into clinical use, establish an efficient and useful viewing station, include diagnostic reports in the archive data, provide wide area network (WAN) capability via ISDN, and establish two-way real-time video between remote sites. This phase has heightened both departmental and institutional thought regarding various issues raised by electronic imaging. Much discussion regarding both present as well as future archival processes has occurred. The use of institutional LAN resources has proven to be adequate for the archival function examined thus far. Experiments to date have shown that use of dedicated resources will be necessary for retrieval activities at even a basic level. This report presents an overview of the background present status and future directions of the project.

Final Status Survey for the Largest Decommissioning Project on Earth

International Nuclear Information System (INIS)

Dubiel, R.W.; Miller, J.; Quayle, D.

2006-01-01

To assist the United States Department of Energy's (US DOE's) re-industrialization efforts at its gaseous diffusion site in Oak Ridge, Tennessee, known as the East Tennessee Technology Park (ETTP), the US DOE awarded a 6-year Decontamination and Decommissioning (D and D) contract to BNG America (formerly BNFL Inc.) in 1997. The ETTP 3-Building D and D Project included the removal and disposition of the materials and equipment from the K-33, K-31, and K-29 Gaseous Diffusion Plant buildings. The three buildings comprise more than 4.8 million square feet (446,000 square meters) of floor surface area and more than 350 million pounds (148 million kilograms) of hazardous and radioactively contaminated material, making it the largest nuclear D and D project in progress anywhere in the world. The logistical hurdles involved in a project of this scope and magnitude required an extensive amount of Engineering and Health Physics professionals. In order to accomplish the Final Status Survey (FSS) for a project of this scope, the speed and efficiency of automated survey equipment was essential. Surveys of floors, structural steel and ceilings up to 60 feet (18 meters) were required. The FSS had to be expanded to include additional remediation and surveys due to characterization surveys and assumptions regarding the nature and extent of contamination provided by the US DOE. Survey design and technical bases had to consider highly variable constituents; including uranium from depleted to low enrichment, variable levels of Technetium-99 and transuranic nuclides, which were introduced into the cascade during the 1960's when recycled uranium (RU) from Savannah River was re-enriched at the facility. The RU was transported to unexpected locations from leaks in the cascade by complex building ventilation patterns. The primary survey tool used for the post remediation and FSS was the Surface Contamination Monitor (SCM) and the associated Survey Information Management System (SIMS

Current status and perspective of advanced loop type fast reactor in fast reactor cycle technology development project

International Nuclear Information System (INIS)

Niwa, Hajime; Aoto, Kazumi; Morishita, Masaki

2007-01-01

After selecting the combination of the sodium-cooled fast reactor (SFR) with oxide fuel, the advanced aqueous reprocessing and the simplified pelletizing fuel fabrication as the most promising concept of FR cycle system, 'Feasibility Study on Commercialized Fast Reactor Cycle Systems' was finalized in 2006. Instead, a new project, Fast Reactor Cycle Technology Development Project (FaCT Project) was launched in Japan focusing on development of the selected concepts. This paper describes the current status and perspective of the advanced loop type SFR system in the FaCT Project, especially on the design requirements, current design as well as the related innovative technologies together with the development road-map. Some considerations on advantages of the advanced loop type design are also described. (authors)

Status of groundwater quality in the Coastal Los Angeles Basin, 2006-California GAMA Priority Basin Project

Science.gov (United States)

Goldrath, Dara; Fram, Miranda S.; Land, Michael; Belitz, Kenneth

2012-01-01

Groundwater quality in the approximately 860-square-mile (2,227-square-kilometer) Coastal Los Angeles Basin study unit (CLAB) was investigated as part of the Priority Basin Project of the Groundwater Ambient Monitoring and Assessment (GAMA) Program. The study area is located in southern California in Los Angeles and Orange Counties. The GAMA Priority Basin Project is being conducted by the California State Water Resources Control Board in collaboration with the U.S. Geological Survey (USGS) and the Lawrence Livermore National Laboratory. The GAMA CLAB study was designed to provide a spatially unbiased assessment of the quality of untreated (raw) groundwater in the primary aquifer system. The assessment is based on water-quality and ancillary data collected in 2006 by the USGS from 69 wells and on water-quality data from the California Department of Public Health (CDPH) database. The primary aquifer system was defined by the depth interval of the wells listed in the CDPH database for the CLAB study unit. The quality of groundwater in the primary aquifer system may be different from that in the shallower or deeper water-bearing zones; shallow groundwater may be more vulnerable to surficial contamination. This study assesses the status of the current quality of the groundwater resource by using data from samples analyzed for volatile organic compounds (VOCs), pesticides, and naturally occurring inorganic constituents, such as major ions and trace elements. This status assessment is intended to characterize the quality of groundwater resources in the primary aquifer system of the CLAB study unit, not the treated drinking water delivered to consumers by water purveyors. Relative-concentrations (sample concentration divided by the health- or aesthetic-based benchmark concentration) were used for evaluating groundwater quality for those constituents that have Federal and (or) California regulatory or non-regulatory benchmarks for drinking-water quality. A relative

Status of initial phase of site-specific seismic monitoring: Basalt Waste Isolation Project

International Nuclear Information System (INIS)

Rohay, A.C.

1981-01-01

This report presents the status of the initial phase of site-specific seismic monitoring work conducted under the Basalt Waste Isolation Project. This work is currently organized under two main elements: (1) a portable array; and (2) a baseline data collection array. Progress toward the development of each array is discussed along with an interpretation of preliminary data obtained from the test of a borehole seismometer at potential repository depths. The text is supplemented by nine figures and one table. 9 figs., 1 tab

Hanford soil partitioning and vapor extraction study

International Nuclear Information System (INIS)

Yonge, D.; Hossain, A.; Cameron, R.; Ford, H.; Storey, C.

1996-07-01

This report describes the testing and results of laboratory experiments conducted to assist the carbon tetrachloride soil vapor extraction project operating in the 200 West Area of the Hanford Site in Richland, Washington. Vapor-phase adsorption and desorption testing was performed using carbon tetrachloride and Hanford Site soils to estimate vapor-soil partitioning and reasonably achievable carbon tetrachloride soil concentrations during active vapor extractions efforts at the 200 West Area. (CCl 4 is used in Pu recovery from aqueous streams.)

Data management for the Clinch River Breeder Reactor Plant Project by use of document status and hold systems

International Nuclear Information System (INIS)

Hunt, C.S.; Beck, A.E.; Akhtar, M.S.

1982-01-01

This paper describes the development, framework, and scope of the Document Status System and the Document Hold System for the Clinch River Breeder Reactor Plant Project. It shows how data are generated at five locations and transmitted to a central computer for processing and storage. The resulting computerized data bank provides reports needed to perform day-to-day management and engineering planning. Those reports also partially satisfy the requirements of the Project's Quality Assurance Program

Hazardous materials in aquatic environments of the Mississippi River Basin. Quarterly project status report, October 1, 1993--December 31, 1993

Energy Technology Data Exchange (ETDEWEB)

1993-12-31

This quarterly project status report discusses research projects being conducted on hazardous materials in aquatic environments of the Mississippi River basin. We continued to seek improvement in our methods of communication and interactions to support the inter-disciplinary, inter-university collaborators within this program. In addition to the defined collaborative research teams, there is increasing interaction among investigators across projects. Planning for the second year of the project has included the development of our internal request for proposals, and refining the review process for selection of proposals for funding.

Technology status in support of refined technical baseline for the Spent Nuclear Fuel project. Revision 1

Energy Technology Data Exchange (ETDEWEB)

Puigh, R.J.; Toffer, H.; Heard, F.J.; Irvin, J.J.; Cooper, T.D.

1995-10-20

The Spent Nuclear Fuel Project (SNFP) has undertaken technology acquisition activities focused on supporting the technical basis for the removal of the N Reactor fuel from the K Basins to an interim storage facility. The purpose of these technology acquisition activities has been to identify technology issues impacting design or safety approval, to establish the strategy for obtaining the necessary information through either existing project activities, or the assignment of new work. A set of specific path options has been identified for each major action proposed for placing the N Reactor fuel into a ``stabilized`` form for interim storage as part of this refined technical basis. This report summarizes the status of technology information acquisition as it relates to key decisions impacting the selection of specific path options. The following specific categories were chosen to characterize and partition the technology information status: hydride issues and ignition, corrosion, hydrogen generation, drying and conditioning, thermal performance, criticality and materials accountability, canister/fuel particulate behavior, and MCO integrity. This report represents a preliminary assessment of the technology information supporting the SNFP. As our understanding of the N Reactor fuel performance develops the technology information supporting the SNFP will be updated and documented in later revisions to this report. Revision 1 represents the incorporation of peer review comments into the original document. The substantive evolution in our understanding of the technical status for the SNFP (except section 3) since July 1995 have not been incorporated into this revision.

Technology status in support of refined technical baseline for the Spent Nuclear Fuel project. Revision 1

International Nuclear Information System (INIS)

Puigh, R.J.; Toffer, H.; Heard, F.J.; Irvin, J.J.; Cooper, T.D.

1995-01-01

The Spent Nuclear Fuel Project (SNFP) has undertaken technology acquisition activities focused on supporting the technical basis for the removal of the N Reactor fuel from the K Basins to an interim storage facility. The purpose of these technology acquisition activities has been to identify technology issues impacting design or safety approval, to establish the strategy for obtaining the necessary information through either existing project activities, or the assignment of new work. A set of specific path options has been identified for each major action proposed for placing the N Reactor fuel into a ''stabilized'' form for interim storage as part of this refined technical basis. This report summarizes the status of technology information acquisition as it relates to key decisions impacting the selection of specific path options. The following specific categories were chosen to characterize and partition the technology information status: hydride issues and ignition, corrosion, hydrogen generation, drying and conditioning, thermal performance, criticality and materials accountability, canister/fuel particulate behavior, and MCO integrity. This report represents a preliminary assessment of the technology information supporting the SNFP. As our understanding of the N Reactor fuel performance develops the technology information supporting the SNFP will be updated and documented in later revisions to this report. Revision 1 represents the incorporation of peer review comments into the original document. The substantive evolution in our understanding of the technical status for the SNFP (except section 3) since July 1995 have not been incorporated into this revision

Esculetin Ameliorates Carbon Tetrachloride-Mediated Hepatic Apoptosis in Rats

Directory of Open Access Journals (Sweden)

Chuan-Sung Chiu

2011-06-01

Full Text Available Esculetin (ESC is a coumarin that is present in several plants such as Fraxinus rhynchophylla and Artemisia capillaris. Our previous study found that FR ethanol extract (FREtOH significantly ameliorated rats’ liver function. This study was intended to investigate the protective mechanism of ESC in hepatic apoptosis in rats induced by carbon tetrachloride. Rat hepatic apoptosis was induced by oral administration of CCl4. All rats were administered orally with CCl4 (20%, 0.5 mL/rat twice a week for 8 weeks. Rats in the ESC groups were treated daily with ESC, and silymarin group were treated daily with silymarin. Serum alanine aminotransferase (ALT, aspartate aminotransferase (AST as well as the activities of the anti-oxidative enzymes glutathione peroxidase (GPx, superoxide dismutase (SOD, and catalase in the liver were measured. In addition, expression of liver apoptosis proteins and anti-apoptotic proteins were detected. ESC (100, 500 mg/kg significantly reduced the elevated activities of serum ALT and AST caused by CCl4 and significantly increased the activities of catalase, GPx and SOD. Furthermore, ESC (100, 500 mg/kg significantly decreased the levels of the proapoptotic proteins (t-Bid, Bak and Bad and significantly increased the levels of the anti-apoptotic proteins (Bcl-2 and Bcl-xL. ESC inhibited the release of cytochrome c from mitochondria. In addition, the levels of activated caspase-9 and activated caspase-3 were significantly decreased in rats treated with ESC than those in rats treated with CCl4 alone. ESC significantly reduced CCl4-induced hepatic apoptosis in rats.

Status of the tandem FEL project development in Israel

International Nuclear Information System (INIS)

Benzvi, I.; Sokolowski, J.; Jerby, E.; Chomski, D.; Ruschin, S.

1989-01-01

The authors report the status of a collaborative research project development aimed toward construction of an IR FEL based on the EN tandem electrostatic accelerator of the Weizmann Institute of Science. A preliminary feasibility demonstration project yielded encouraging progress in three aspects: (1) Electron gun and accelerator conversion: A 50-kV 1-A electron gun injector was designed, built, tested, and assembled on the 6-MeV tandem accelerator which was previously converted and conditioned to operate as an electron accelerator in a positively charged HV terminal configuration. Contrary to the configuration of the only electrostatic accelerator FEL demonstrated so far, the electron gun and multistage depressed collector are connected to the ground, and the wiggler is placed in the HV terminal of the straight geometry tandem accelerator. This configuration promises to provide a high current high quality e-beam. (2) Electron-beam transport: The first installation of the electron optical beam recovery system yielded transport efficiency of 80%. Substantial improvement is expected with planned electron optics modifications. An effect, highly significant for realizing long pulse (quasi-cw) FEL operation, was observed experimentally. Due to the damping effect of the accelerator column capacitance network, the voltage terminal stayed constant for milliseconds even with poor beam transport efficiency. This points to the possibility of developing a long pulse FEL which may operate at a single longitudinal mode. (3) Wiggler development: A conventional 4.4-cm period SmCo planar wiggler was acquired and evaluated using a recently constructed floating wire magnetic field measurement setup

Effect of carbon tetrachloride and Liv-52 on the clearance rate of 131I-Rose bengal in rat liver

International Nuclear Information System (INIS)

Dhawan, D.; Goel, A.; Karkara, K.

1991-01-01

131 I-Rose bengal clearance test has been immensely used for the clinical assessment of functional hepatic abnormalities. It has been observed that external collimated scintillation probe employing 131 I-Rose bengal is a rapid and less erroneous way of assessing polygonal cell function in liver. The present study demonstrates the protection of liver by Liv-52 from the deleterious effects of carbon tetrachloride (CCl 4 ) by determining the biological half-life of 131 I-Rose bengal in male albino rats. An increase in the biological half-life of the radio-iodinated dye was observed following CCl 4 intoxication which was reversed by Liv-52 treatment. (author). 15 refs., 2 tabs

Mechanisms of circadian rhythmicity of carbon tetrachloride hepatotoxicity.

Science.gov (United States)

Bruckner, James V; Ramanathan, Raghupathy; Lee, K Monica; Muralidhara, Srinivasa

2002-01-01

The toxicity of carbon tetrachloride (CCl(4)) and certain other chemicals varies over a 24-h period. Because the metabolism of some drugs follows a diurnal rhythm, it was decided to investigate whether the hepatic metabolic activation of CCl(4) was rhythmic and coincided in time with maximum susceptibility to CCl(4) hepatotoxicity. A related objective was to test the hypothesis that abstinence from food during the sleep cycle results in lipolysis and formation of acetone, which participates in induction of liver microsomal cytochrome P450IIE1 (CYP2E1), resulting in a diurnal increase in CCl(4) metabolic activation and acute liver injury. Groups of fed and fasted male Sprague-Dawley rats were given a single oral dose of 800 mg of CCl(4)/kg at 2- to 4-h intervals over a 24-h period. Serum enzyme activities, measured 24 h post dosing as indices of acute liver injury, exhibited distinct maxima in both fed and fasted animals dosed with CCl(4) near the beginning of their dark/active cycle. Blood acetone, hepatic CYP2E1 activity, and covalent binding of (14)CCl(4)/metabolites to hepatic microsomal proteins in untreated rats fed ad libitum followed circadian rhythms similar to that of susceptibility to CCl(4). Parallel fluctuations of greater amplitude were seen in rats fasted for 24 h. Hepatic glutathione levels were lowest at the time of greatest susceptibility to CCl(4). Acetone dose-response experiments showed high correlations between blood acetone levels, CYP2E1 induction, and CCl(4)-induced liver injury. Pretreatment with diallyl sulfide suppressed CYP2E1 and abolished the circadian rhythmicity of susceptibility to CCl(4). These findings provide additional support for acetone's physiological role in CYP2E1 induction and for CYP2E1's role in modulating CCl(4) chronotoxicity in rats.

Capital Improvement Program (CIP) Project Status

Data.gov (United States)

Montgomery County of Maryland — This dataset includes pertinent information relating to a capital project’s status administered by the Department of Transportation and the Department of General...

Decontamination and decommissioning project status of the TRIGA mark-2±3 research reactors

International Nuclear Information System (INIS)

Jung, K. J.; Baek, S. T.; Jung, W. S.; Park, S. K.; Jung, K. H.

1999-01-01

TRIGA Mark-II, the first research reactor in Korea, has operated since 1962, and the second one, TRIGA Mark-III since 1972. Both of them had their operation phased out in 1995 due to their lives and operation of the new research reactor, HANARO at the Korea Atomic Energy Research Institute (KAERI) in Taejeon. Decontamination and decommissioning (D and D) project of the TRIGA Mark-II and Mark-III was started in January 1997 and will be completed in December 2002. In the first year of the project, work was performed in preparation of the decommissioning plan, start of the environmental impact assessment and setup licensing procedure and documentation for the project with cooperation of Korea Institute of Nuclear Safety (KINS). In 1998, Hyundai Engineering Company (HEC) is the main contractor to do design and licensing documentation for the D and D of both reactors. British Nuclear Fuels plc (BNFL) is technical assisting partner of HEC. The decommissioning plan document was submitted to the Ministry of Science and Technology (MOST) for the decommissioning license in December 1998, and it expecting to be issued a license at the end of September 1999. The goal of this project is to release the reactor site and buildings as an unrestricted area. This paper summarizes current status and future plan for the D and D project

Decontamination and decommissioning project status of the TRIGA Mark II and III in Korea

International Nuclear Information System (INIS)

Paik, S.T.; Park, S.K.; Chung, K.W.; Chung, U.S.; Jung, K.J.

1999-01-01

TRIGA Mark-II, the first research reactor in Korea, has operated since 1962, and the second one, TRIGA Mark-III since 1972. Both of them had their operation phased out in 1995 due to their lives and operation of the new research reactor, HANARO (High-flux Advanced Neutron Application Reactor) at the Korea Atomic Energy Institute (KAERI) in Taejon. Decontamination and decommissioning (D and D) project of TRIGA Mark-II and Mark-III was started in January 1997 and will be completed in December 2002. The first year of the project, work was performed in preparation of the decommissioning plan, start of the environmental impact assessment and setup licensing procedure and documentation for the project with cooperation of Korea Institute of Nuclear Safety (KINS). Hyundai Engineering Company (HEC) is the main contractor to do design and licensing documentation for the D and D of both reactors. British Nuclear Fuels plc (BNFL) is the technical assisting partner of HEC. The decommissioning plan document was submitted to the Ministry of Since and Technology (MOST) for the decommissioning license in December 1998, and it expecting to be issued a license in mid 1999. The goal of this project is to release the reactor site and buildings as an unrestricted area. This paper summarizes current status and future plan for the D and D project. (author)

Advanced Monitoring Systems Initiative Project Achievements for Environmental Restoration and Waste Management

International Nuclear Information System (INIS)

Hohman, E.H.; Lohrstorfer, C.L.; Venedam, R.J.; Weeks, S.J.; Fannin, C.R.

2006-01-01

The Advanced Monitoring Systems Initiative (AMSI) project has been in existence since 2002. In this short time period, AMSI has successfully developed, tested and/or demonstrated over 30 advanced sensors and monitoring systems for applications in environmental restoration, waste management and other areas of national interest. This presentation summarizes the AMSI project, and gives examples of recent successes. The purpose of the presentation is to make Symposium attendees aware of AMSI's capabilities and experience, for possible use in the future. Example successes include the following: - Automated hexavalent chromium (Cr(VI)) monitoring in wells alongside the Columbia River; - Atmospheric chemical sensor array for remote, real-time plume tracking; - Wireless sensor platform for long-term monitoring of subsurface moisture; - Embedded piezo-resistive micro-cantilever (EPM) units for carbon tetrachloride (CCl 4 ) and hydrogen cyanide (HCN) detection; - 'iHistorian' for efficient, real-time data management of chemical releases. (authors)

Project studies

DEFF Research Database (Denmark)

Geraldi, Joana; Söderlund, Jonas

2018-01-01

Project organising is a growing field of scholarly inquiry and management practice. In recent years, two important developments have influenced this field: (1) the study and practice of projects have extended their level of analysis from mainly focussing on individual projects to focussing on micro......, and of the explanations of project practices they could offer. To discuss avenues for future research on projects and project practice, this paper suggests the notion of project studies to better grasp the status of our field. We combine these two sets of ideas to analyse the status and future options for advancing...... project research: (1) levels of analysis; and (2) type of research. Analysing recent developments within project studies, we observe the emergence of what we refer to as type 3 research, which reconciles the need for theoretical development and engagement with practice. Type 3 research suggests pragmatic...

Constraining the carbon tetrachloride (CCl4) budget using its global trend and inter-hemispheric gradient

Science.gov (United States)

Liang, Qing; Newman, Paul A.; Daniel, John S.; Reimann, Stefan; Hall, Bradley D.; Dutton, Geoff; Kuijpers, Lambert J. M.

2014-07-01

Carbon tetrachloride (CCl4) is a major anthropogenic ozone-depleting substance and greenhouse gas and has been regulated under the Montreal Protocol. However, the near-zero 2007-2012 emissions estimate based on the UNEP reported production and feedstock usage cannot be reconciled with the observed slow decline of atmospheric concentrations and the inter-hemispheric gradient (IHG) for CCl4. Our 3-D model simulations suggest that the observed IHG (1.5 ± 0.2 ppt for 2000-2012) is primarily caused by ongoing current emissions, while ocean and soil losses and stratosphere-troposphere exchange together contribute a small negative gradient (~0 - -0.3 ppt). Using the observed CCl4 global trend and IHG, we deduce that the mean global emissions for the 2000-2012 period are 393445 Gg/yr (~30% of the peak 1980s emissions) and a corresponding total lifetime of 353732 years.

The Ongkharak Nuclear Research Center (ONRC) research reactor project: a status review

International Nuclear Information System (INIS)

Rusch, R.; Jacobi, A. Jr.; Yamkate, P.

2001-01-01

The new Ongkharak Nuclear Research Center in the vicinity of Bangkok, Thailand is planned to replace the more than 30 years old facilities located in the Chatuchak district, Bangkok. An international team led by general atomics (GA) is designing and constructing the new research complex. It comprises a 10 MW TRIGA type reactor, an isotope production and a centralized waste processing and storage facility. Electrowatt-Ekono Ltd. was hired by the Thai Government Agency, the Office of Atomic Energy for Peace (OAEP), as a consultant to the project. As the project is now approaching the end of its 4 th year, it now stands at a decisive turning point. Basic design is nearly completed and detailed design is well advanced. The turnkey part of the contract including the reactor island, the isotope and waste facilities are still awaiting the issuance of the Construction Permit. Significant progress has been made on the other part of the project, which includes all the supporting infrastructure facilities. The Preliminary Safety Analysis Report (PSAR), prepared by GA, has been reviewed by various parties, including by nuclear safety experts from the IAEA, which has provided continuous support to the OAEP. Experts from the Argonne National Laboratory have been involved in the reviews as well. The PSAR is now under consideration at the Nuclear Facility Safety Sub-Committee (NFSS) of the Thai Atomic Energy for Peace Commission for issuing the Construction Permit of the ONRC Research Reactor. The following paper gives an overview of the project and its present status, outlining the features of the planned facilities and the issues the project is presently struggling with. Major lessons of the past 4 years are highlighted and an outlook into the future is attempted. (orig.)

Subchronic inhalation of carbon tetrachloride alters the tissue retention of acutely inhaled plutonium-239 nitrate in F344 rats and syrian golden hamsters

International Nuclear Information System (INIS)

Benson, J.M.; Barr, E.B.; Lundgren, D.L.

1995-01-01

Carbon tetrachloride (CCl 4 ) has been used extensively in the nuclear weapons industry, so it is likely that nuclear plant workers have been exposed to both CCl 4 and plutonium compounds. Future exposures may occur during open-quotes cleanupclose quotes operations at weapons productions sites such as the Hanford, Washington, and Rocky Flats, Colorado, facilities. Inhalation of 20 and 100 ppm CCl 4 by hamsters reduces uptake of 239 Pu solubilized from lung, shunting the 239 Pu to the skeleton

Soil-plant water status and wine quality: the case study of Aglianico wine (the ZOViSA project)

Science.gov (United States)

Bonfante, Antonello; Manna, Piero; Albrizio, Rossella; Basile, Angelo; Agrillo, Antonietta; De Mascellis, Roberto; Caputo, Pellegrina; Delle Cave, Aniello; Gambuti, Angelita; Giorio, Pasquale; Guida, Gianpiero; Minieri, Luciana; Moio, Luigi; Orefice, Nadia; Terribile, Fabio

2014-05-01

The terroir analysis, aiming to achieve a better use of environmental features with respect to plant requirement and wine production, needs to be strongly rooted on hydropedology. In fact, the relations between wine quality and soil moisture regime during the cropping season is well established. The ZOViSA Project (Viticultural zoning at farm scale) tests a new physically oriented approach to terroir analysis based on the relations between the soil-plant water status and wine quality. The project is conducted in southern Italy in the farm Quintodecimo of Mirabella Eclano (AV) located in the Campania region, devoted to quality Aglianico red wine production (DOC). The soil spatial distribution of study area (about 3 ha) was recognized by classical soil survey and geophysics scan by EM38DD; then the soil-plant water status was monitored for three years in two experimental plots from two different soils (Cambisol and Calcisol). Daily climate variables (temperature, solar radiation, rainfall, wind), daily soil water variables (through TDR probes and tensiometers), crop development (biometric and physiological parameters), and grape must and wine quality were monitored. The agro-hydrological model SWAP was calibrated and applied in the two experimental plots to estimate soil-plant water status in different crop phenological stages. The effects of crop water status on crop response and wine quality was evaluated in two different pedo-systems, comparing the crop water stress index with both: crop physiological measurements (leaf gas exchange, leaf water potential, chlorophyll content, LAI measurement), grape bunches measurements (berry weight, sugar content, titratable acidity, etc.) and wine quality (aromatic response). Finally a "spatial application" of the model was carried out and different terroirs defined.

The Columbia River Protection Supplemental Technologies Quality Assurance Project Plan

International Nuclear Information System (INIS)

Fix, Anne

2007-01-01

The U.S. Department of Energy (DOE) has conducted interim groundwater remedial activities on the Hanford Site since the mid-1990s for several groundwater contamination plumes. DOE established the Columbia River Protection Supplemental Technologies Project (Technologies Project) in 2006 to evaluate alternative treatment technologies. The objectives for the technology project are as follows: develop a 300 Area polyphosphate treatability test to immobilize uranium, design and test infiltration of a phosphate/apatite technology for Sr-90 at 100-N, perform carbon tetrachloride and chloroform attenuation parameter studies, perform vadose zone chromium characterization and geochemistry studies, perform in situ biostimulation of chromium studies for a reducing barrier at 100-D, and perform a treatability test for phytoremediation for Sr-90 at 100-N. This document provides the quality assurance guidelines that will be followed by the Technologies Project. This Quality Assurance Project Plan is based on the quality assurance requirements of DOE Order 414.1C, Quality Assurance, and 10 CFR 830, Subpart A--Quality Assurance Requirements as delineated in Pacific Northwest National Laboratory?s Standards-Based Management System. In addition, the technology project is subject to the Environmental Protection Agency (EPA) Requirements for Quality Assurance Project Plans (EPA/240/B-01/003, QA/R-5). The Hanford Analytical Services Quality Assurance Requirements Documents (HASQARD, DOE/RL-96-68) apply to portions of this project and to the subcontractors. HASQARD requirements are discussed within applicable sections of this plan.

Project Radiation Protection East. Swedish cooperation program for radiation protection in Eastern and Central Europe. Status Report, March 1996

International Nuclear Information System (INIS)

Snihs, J.O.; Johansson, Mai; Grapengiesser, S.; Bennerstedt, T.

1996-04-01

Until now the Swedish program for radiation protection work in central and Eastern europe has been granted 55 MSEK by the Swedish government. The projects are assessed, planned and performed in close cooperation with partner organizations in the East. Since 1994, radiation protection cooperation concerning the former Soviet Navy training reactors in Paldiski, Estonia, is included in Radiation Protection East. The government has granted 8 MSEK for this purpose. This report presents a summary over some 150 projects, their status, allocated funds and their distribution over countries and project areas. The presentation is updated up to March 1996. 7 figs

Emissions estimates of carbon tetrachloride for 1992-2014 in China.

Science.gov (United States)

Bie, Pengju; Fang, Xuekun; Li, Zhifang; Wang, Ziyuan; Hu, Jianxin

2017-05-01

Discrepancies in emission estimates of carbon tetrachloride (CCl 4 , CTC), between bottom-up and top-down methods, have been shown since the 1990s at both the global and regional scale. This study estimates the emissions of China from 1992 to 2014 based on emission functions and aggregated activity information given reasonable uncertainties. The results show that emissions increase from 7.3 Gg/yr (5.6-9.1 Gg/yr at 95% confidential interval) to 14.0 (9.1-19.5) Gg/yr with a growth rate of 6.7 (1.9-11.4) %/yr during 1992-2002 and then decrease to a minimum of 4.3 (1.9-8.0) Gg/yr in 2011. More than 54% of the emissions during 1992-2009 are from the process agents sector. The estimates are comparable with those of other studies and those in this study based on observations during 2011-2014 using the interspecies correlation method. China's contribution to global emissions increases from 7.5% to 19.5% during 1992-2009, but the contribution is reduced to 9.9% and 8.0% in 2010 and 2011, respectively, indicating the effectiveness of compliance with the Montreal Protocol and its subsequent Amendments and Adjustments, whereby CTC emissions are phased-out. The results of this study are beneficial for narrowing the gap between bottom-up estimates and top-down emission calculations of CTC in China. Copyright © 2017 Elsevier Ltd. All rights reserved.

Current status of JMTR refurbishment project

International Nuclear Information System (INIS)

Kaminaga, Masanori; Niimi, Motoji; Hori, Naohiko; Takahashi, Kunihiro; Kanno, Masaru; Nakagawa, Tetsuya; Nagao, Yoshiharu; Ishihara, Masahiro; Kawamura, Hiroshi

2010-02-01

The JMTR is a light water moderated and cooled, beryllium reflected tank- type reactor using LUE silicide plate-type fuels. Its thermal power is 50 MW, maximum thermal and fast neutron flux is 4x10 18 m -2 s -1 . First criticality was achieved in March 1968, and its operation was stopped from August, 2006 for the refurbishment. The refurbishment is scheduled from the beginning of FY2007 to the end of FY2010. The renewed and upgraded JMTR will be re-started from FY2011. An investigation on aged components (aged-investigation) was carried out for concrete structures of the JMTR reactor building, exhaust stack, etc., and for tanks in the primary cooling system, heat exchangers, pipes in the secondary cooling system, cooling tower, emergency generators and so on, in order to identify their integrity. The aged-investigation was carried out at the beginning of FY2007. As a result, some components were decided to replace from viewpoints of future maintenance and improvement of reliability, and some components or structures were decided to repair. A visual inspection of inner side of the pressure vessel was carried out using an underwater camera in FY2008, and no serious damage was observed. Up to now, refurbishment works are in progress according to the planned schedule. In FY2009, motors of primary cooling pumps, secondary cooling pumps, motors of drain pumps, pump in the primary water transfer line to the water purification system, beryllium reflector frame, low-voltage motor control centers are to be replaced. A nuclear instrumentation system, process control system, safety protection system and so on are to be replaced in FY2010. In this paper, current status of JMTR refurbishment project is presented. (author)

Current status of decommissioning projects and their strategies in advanced countries

Energy Technology Data Exchange (ETDEWEB)

Chung, U. S.; Lee, K. W.; Hwang, D. S.; Park, S. K.; Hwang, S. T.; Paik, S. T.; Park, J. H.; Choi, Y. D.; Chung, K. H.; Lee, K. I.; Hong, S. B

2007-06-15

At the Korea Atomic Energy Research Institute(KAERI), two projects for decommissioning of the research reactors and uranium conversion plant are carried out. The number of nuclear facilities to be dismantled will be much increased in future and the decommissioning industries will be enlarged. Keeping pace with this increasing tendency, each country formulated their own strategies and regulation systems, and applied their own technologies. The international organizations such as the IAEA and the OECD/NEA also prepared standards in technologies and regulation upon decommissioning and recommended to adopt them to the decommissioning projects. These strategies and technologies are very different country by country due to the different site dependent conditions and it will not be reasonable to evaluate their merits and weakness. The world wide status of the decommissioning, highlighted on that of 5 countries of USA, UK, France, Germany and Japan because they are advanced counties in nuclear industries, are summarized and their site specific conditions are evaluated. The scopes of the evaluation are decommissioning strategies, licensing procedures and requirements focused on decommissioning plan, waste management, technology development and so on. The detailed decommissioning progresses of several typical example sites were introduced. The activities on decommissioning field of the international organization, increased according to the enlarged decommissioning industries, are also summarized.

Current status of decommissioning projects and their strategies in advanced countries

International Nuclear Information System (INIS)

Chung, U. S.; Lee, K. W.; Hwang, D. S.; Park, S. K.; Hwang, S. T.; Paik, S. T.; Park, J. H.; Choi, Y. D.; Chung, K. H.; Lee, K. I.; Hong, S. B.

2007-06-01

At the Korea Atomic Energy Research Institute(KAERI), two projects for decommissioning of the research reactors and uranium conversion plant are carried out. The number of nuclear facilities to be dismantled will be much increased in future and the decommissioning industries will be enlarged. Keeping pace with this increasing tendency, each country formulated their own strategies and regulation systems, and applied their own technologies. The international organizations such as the IAEA and the OECD/NEA also prepared standards in technologies and regulation upon decommissioning and recommended to adopt them to the decommissioning projects. These strategies and technologies are very different country by country due to the different site dependent conditions and it will not be reasonable to evaluate their merits and weakness. The world wide status of the decommissioning, highlighted on that of 5 countries of USA, UK, France, Germany and Japan because they are advanced counties in nuclear industries, are summarized and their site specific conditions are evaluated. The scopes of the evaluation are decommissioning strategies, licensing procedures and requirements focused on decommissioning plan, waste management, technology development and so on. The detailed decommissioning progresses of several typical example sites were introduced. The activities on decommissioning field of the international organization, increased according to the enlarged decommissioning industries, are also summarized

The status report on the nuclear data project in Korea

Energy Technology Data Exchange (ETDEWEB)

Kim, G.N.; Baek, W.Y.; Kang, H.S.; Choi, J.Y.; Cho, M.H.; Ko, I.S.; Namkung, W. [Pohang Accelerator Laboratory, POSTECH, Pohang (Korea, Republic of); Chang, J.H.

1999-03-01

The nuclear data project as one of the nation-wide nuclear R and D programs was launched by the Korea Atomic Energy Research Institute (KAERI) in 1996. Its main goals are to establish a nuclear data system, to construct the infrastructure for the nuclear data productions and evaluations, and to develop a highly reliable nuclear data system. In order to build the infrastructure for the nuclear data production, KAERI wants to build an intense pulsed neutron source by utilizing accelerator facilities, technologies, and manpower at the Pohang Accelerator Laboratory (PAL). The PAL proposed the Pohang Neutron Facility (PNF), which consists of a 100-MeV electron linac, a water-cooled Ta target, and at least three different time-of-flight (TOF) paths. The 100-MeV electron linac was designed and constructed based on experiences obtained from construction and operation of the 2-GeV linac at PAL. We report a status report on the nuclear data production and evaluation in Korea. (author)

Groundwater impact assessment report for the 216-Z-20 Crib, 200 West Area

International Nuclear Information System (INIS)

Johnson, V.G.

1993-10-01

As required by the Hanford Federal Facility Agreement and Consent Order ([Tri-Party Agreement] Milestone M-17-00A), this report assesses the impact of wastewater discharges to the 216-Z-20 Crib on groundwater quality. The assessment reported herein extends the initial analysis conducted from 1989 through 1990 for the Liquid Effluent Study Final Project Report. Three primary issues are addressed in response to regulator concerns with the initial analysis: The magnitude and status of the soil column transuranic inventory. Potential interactions of wastewater with carbon tetrachloride from adjacent facilities. Preferential pathways created by unsealed monitoring wells

Groundwater impact assessment report for the 216-Z-20 Crib, 200 West Area

Energy Technology Data Exchange (ETDEWEB)

Johnson, V.G.

1993-10-01

As required by the Hanford Federal Facility Agreement and Consent Order ([Tri-Party Agreement] Milestone M-17-00A), this report assesses the impact of wastewater discharges to the 216-Z-20 Crib on groundwater quality. The assessment reported herein extends the initial analysis conducted from 1989 through 1990 for the Liquid Effluent Study Final Project Report. Three primary issues are addressed in response to regulator concerns with the initial analysis: The magnitude and status of the soil column transuranic inventory. Potential interactions of wastewater with carbon tetrachloride from adjacent facilities. Preferential pathways created by unsealed monitoring wells.

Status report EFF and EAF projects

International Nuclear Information System (INIS)

Gruppelaar, H.; Kopecky, J.

1990-08-01

The European Fusion File (EFF) project and the associated European Activation File Project (EAF) are sponsored by the European Community's Fusion Technology Programme. The 1st programme is directed to the short-term needs of the NET team, which designs the Next European Torus, while the 2nd program is directed to long-term needs in the development of a Fusion Demonstration Reactor, in particular in connection with the study of low-activation materials. Various European laboratories participate in this project. The programme of the EFF-project is in its 2nd phase, after the successful completion of the EFF-1 data file. The emphasis on the 1st phase was on the improvement of the tritium breeding and neutron multiplication cross sections, while the 2nd phase emphasizes the improvement of a shielding data base. The progress of this 2nd phase is described. (author). 1 tab

Subchronic inhalation of carbon tetrachloride alters the tissue retention of acutely inhaled plutonium-239 nitrate in F344 rats and syrian golden hamsters

Energy Technology Data Exchange (ETDEWEB)

Benson, J.M.; Barr, E.B.; Lundgren, D.L. [and others

1995-12-01

Carbon tetrachloride (CCl{sub 4}) has been used extensively in the nuclear weapons industry, so it is likely that nuclear plant workers have been exposed to both CCl{sub 4} and plutonium compounds. Future exposures may occur during {open_quotes}cleanup{close_quotes} operations at weapons productions sites such as the Hanford, Washington, and Rocky Flats, Colorado, facilities. Inhalation of 20 and 100 ppm CCl{sub 4} by hamsters reduces uptake of {sup 239}Pu solubilized from lung, shunting the {sup 239}Pu to the skeleton.

Status Report: Mathematics Curriculum-Development Projects Today

Science.gov (United States)

Arithmetic Teacher, 1972

1972-01-01

Brief reports on the Cambridge Conference on School Mathematics, Comprehensive School Mathematics Program, Computer-Assisted Instruction Projects at Stanford, Individually Prescribed Instruction Project, The Madison Project, Mathematics/Science Learning System, MINNEMAST, and School Mathematics Study Group. (MM)

Chemical Composition, Antimicrobial Activity of Propolis Ethanolic Extract and Its Improving Role of Biochemical Changes Induced by Carbon tetrachloride in Male Albino Rats

International Nuclear Information System (INIS)

Gabr, S.A.; Abbas, M.M.; Ouda, S.M.; Abdeldaiem, M.H.

2009-01-01

Propolis (bee glue) is a sticky substance that is collected from plants by honeybees. Due to biological and pharmacological activities, it has been extensively used in folk medicine. The purpose of this study was to investigate the chemical composition, the antimicrobial activity and possible protective effects of ethanolic extract of propolis on carbon tetrachloride (CCl 4 )-induced biological damages in rats. The studied rats were allotted to four equal groups (6 rats each) : Group 1 served as control and was given the vehicle (Tween 80 dissolved in distilled water, 1:100 ) orally for 21 consecutive days after which they were sacrificed , group 2 treated orally with ethanolic extract of popolis (100μg/rat) for 21 successive days, group 3 ( CCl 4 - treated group) administered orally with a single dose (0.5 ml/kg body weight) of carbon tetrachloride (mixed with an equal volume of olive oil) and group 4 (protected group) was treated with propolis extract (100μg/rat) for 21 successive days, after one hour of the last dose of the treatment, a single dose of CCl 4 (0.5 ml/kg body weight) was given. Then all animals were sacrificed, 24 hr post experimental design period for each group. Our results revealed that, fourteen compounds were identified by chromatography-mass spectrometry analysis (GC- MS analysis). Propolis ethanolic extract inhibited the growth of six from the tested microorganisms including bacteria and fungi at 5 mg/ml against E. coli and B. subtilis and 20 mg/ml against S. aureus, P. aeruginosa, Penicillium italicum and Candida albicans, while it has no effect on A. fumigatus and Syncephalstrum racemasum. In experimental animals, Leucocytic counts and platelets, in addition, AST, ALT, CK and LDH were significantly increased, meanwhile, triiodothyronine (T3) and thyroxine (T4) level was decreased in CCl 4 treated rats (group 3) compared to the control (group 1). Protection with ethanolic extract of propolis to rats received CCl 4 (group 4) ameliorated

Current status of food irradiation in overseas (2013). From the meeting report of RCA food irradiation project

International Nuclear Information System (INIS)

Todoriki, Setsuko

2013-01-01

The report introduces the activity of RCA (Regional Cooperative Agreement for Research Development and Training Related to Nuclear Science and Technology for Asia and Pacific) food irradiation project (RAS/5/057) and information obtained at the two workshops on current status of Asia and Pacific areas together with EU, USA and Japan. Also current trends of RAS/5/057 Implementing Best Practices for food irradiation for plant sanitary and phytosanitary purposes are described. Amount of food irradiation products of RCA member countries, minimum adopted doses for quarantine harmful insects (70 to 232 Gy) and import amount of fruits of USA (79 to 5500 tons) are tabulated. Finally current status of Japan is explained. (S. Ohno)

Status of Standardization Projects

Science.gov (United States)

1991-06-30

MCA GL G4 913 914 914 A GL SA 50 SS N D 8915 TOTAL- 6. DELINQUENT- 0. STATUS CODES: A- 5, G- 1. Y- 0, Z- 0 8920 0539 MIL R 35084A RICE INSTANT ENRICHED...44171GL CARROTS GLA POW GL H5 904 914 914 A N D 8940 A693 MIL N 44178GL NOODLES PARMESAN AND ROMA GL H5 904 914 914 A N D 8940 A694 MIL P 44181GL PIE...20184 COFFEE INSTANT GL B4 A 893 903 913 A GL SA 50 SS U B 8955 0062 MIL T 3527D I NOT 1 TEA INSTANT GL H5 912 921 921 A GL SA 50 SS N 8955 TOTAL- 2

Hepatoprotective effects of Arctium lappa on carbon tetrachloride- and acetaminophen-induced liver damage.

Science.gov (United States)

Lin, S C; Chung, T C; Lin, C C; Ueng, T H; Lin, Y H; Lin, S Y; Wang, L Y

2000-01-01

The root of Arctium lappa Linne (A. lappa) (Compositae), a perennial herb, has been cultivated for a long time as a popular vegetable. In order to investigate the hepatoprotective effects of A. lappa, male ICR mice were injected with carbon tetrachloride (CCl4, 32 microl/kg, i.p.) or acetaminophen (600 mg/kg, i.p.). A. lappa suppressed the SGOT and SGPT elevations induced by CCl4 or acetaminophen in a dose-dependent manner and alleviated the severity of liver damage based on histopathological observations. In an attempt to elucidate the possible mechanism(s) of this hepatoprotective effect, glutathione (GSH), cytochrome P-450 (P-450) and malondialdehyde (MDA) contents were studied. A. lappa reversed the decrease in GSH and P-450 induced by CCl4 and acetaminophen. It was also found that A. lappa decreased the malondialdehyde (MDA) content in CCl4 or acetaminophen-intoxicated mice. From these results, it was suggested that A. lappa could protect the liver cells from CCl4 or acetaminophen-induced liver damages, perhaps by its antioxidative effect on hepatocytes, hence eliminating the deleterious effects of toxic metabolites from CCl4 or acetaminophen.

Status and Mission Applicability of NASA's In-Space Propulsion Technology Project

Science.gov (United States)

Anderson, David J.; Munk, Michelle M.; Dankanich, John; Pencil, Eric; Liou, Larry

2009-01-01

The In-Space Propulsion Technology (ISPT) project develops propulsion technologies that will enable or enhance NASA robotic science missions. Since 2001, the ISPT project developed and delivered products to assist technology infusion and quantify mission applicability and benefits through mission analysis and tools. These in-space propulsion technologies are applicable, and potentially enabling for flagship destinations currently under evaluation, as well as having broad applicability to future Discovery and New Frontiers mission solicitations. This paper provides status of the technology development, near-term mission benefits, applicability, and availability of in-space propulsion technologies in the areas of advanced chemical thrusters, electric propulsion, aerocapture, and systems analysis tools. The current chemical propulsion investment is on the high-temperature Advanced Material Bipropellant Rocket (AMBR) engine providing higher performance for lower cost. Investments in electric propulsion technologies focused on completing NASA's Evolutionary Xenon Thruster (NEXT) ion propulsion system, a 0.6-7 kW throttle-able gridded ion system, and the High Voltage Hall Accelerator (HiVHAC) thruster, which is a mid-term product specifically designed for a low-cost electric propulsion option. Aerocapture investments developed a family of thermal protections system materials and structures; guidance, navigation, and control models of blunt-body rigid aeroshells; atmospheric models for Earth, Titan, Mars and Venus; and models for aerothermal effects. In 2009 ISPT started the development of propulsion technologies that would enable future sample return missions. The paper describes the ISPT project's future focus on propulsion for sample return missions. The future technology development areas for ISPT is: Planetary Ascent Vehicles (PAV), with a Mars Ascent Vehicle (MAV) being the initial development focus; multi-mission technologies for Earth Entry Vehicles (MMEEV) needed

Structure of methylene chloride addition product to zirconium tetrachloride complex with 1-tert.-butyl-2,4,4-trimethyl-2-thio-trimethylsilyl-1,3,2,4-diazaphosphasilatedine

International Nuclear Information System (INIS)

Brusilovets, A.I.; Rusanov, Eh.B.; Chernega, A.N.

1995-01-01

Complex of zirconium tetrachloride with 1-tert.-butyl-2,4,4-trimethyl--2-thio-3-trimethyl-silyl-1,3,2,4-diazaphosphasilatedine interacts with methylene chloride with formation of bis[3-tert.-butyl-2,4,4-trimethyl-1--trimethylsilyl-2-chloremethylthio-1,3,2,4-diazaphosphasilatedinium] decachlorodizirconate. Specific features of crystal and molecular structure of the compound prepared have been studied by X-ray diffraction method. 21 refs.; 2 figs.; 2 tabs

Medical Data Architecture Project Status

Science.gov (United States)

Krihak, M.; Middour, C.; Lindsey, A.; Marker, N.; Wolfe, S.; Winther, S.; Ronzano, K.; Bolles, D.; Toscano, W.; Shaw, T.

2017-01-01

The Medical Data Architecture (MDA) project supports the Exploration Medical Capability (ExMC) risk to minimize or reduce the risk of adverse health outcomes and decrements in performance due to in-flight medical capabilities on human exploration missions. To mitigate this risk, the ExMC MDA project addresses the technical limitations identified in ExMC Gap Med 07: We do not have the capability to comprehensively process medically-relevant information to support medical operations during exploration missions. This gap identifies that the current International Space Station (ISS) medical data management includes a combination of data collection and distribution methods that are minimally integrated with on-board medical devices and systems. Furthermore, there are variety of data sources and methods of data collection. For an exploration mission, the seamless management of such data will enable an increasingly autonomous crew than the current ISS paradigm. The MDA will develop capabilities that support automated data collection, and the necessary functionality and challenges in executing a self-contained medical system that approaches crew health care delivery without assistance from ground support. To attain this goal, the first year of the MDA project focused on reducing technical risk, developing documentation and instituting iterative development processes that established the basis for the first version of MDA software (or Test Bed 1). Test Bed 1 is based on a nominal operations scenario authored by the ExMC Element Scientist. This narrative was decomposed into a Concept of Operations that formed the basis for Test Bed 1 requirements. These requirements were successfully vetted through the MDA Test Bed 1 System Requirements Review, which permitted the MDA project to begin software code development and component integration. This paper highlights the MDA objectives, development processes, and accomplishments, and identifies the fiscal year 2017 milestones and

Baltic NPP Project specifics and current status

International Nuclear Information System (INIS)

2011-01-01

Project overview: 2 x 1194 MW Units (AES-2006 series); Location in Kaliningrad region of the; Russian Federation; Operation dates: Unit 1 – Oct 2016; Unit 2 – Apr 2018; Site preparatory works ongoing. This is first NPP project in the Russian Federation providing opportunity for participation of foreign investors. Foreign investors may acquire up to 49% share. Cross-border transmission lines developed under separate project with participation of foreign investors. Conclusion: At the selected set of assumptions, the project is financially feasible in all scenarios

Photovoltaic concentrator technology development project. Sixth project integration meeting

Energy Technology Data Exchange (ETDEWEB)

None

1980-10-01

Thirty-three abstracts and short papers are presented which describe the current status of research, development, and demonstration of concentrator solar cell technology. Solar concentrators discussed include the parabolic trough, linear focus Fresnel lens, point focus Fresnel lens, and the parabolic dish. Solar cells studied include silicon, GaAs, and AlGaAs. Research on multiple junction cells, combined photovoltaic/thermal collectors, back contact solar cells, and beam splitter modules is described. Concentrator solar cell demonstration programs are reported. Contractor status summaries are given for 33 US DOE concentrator solar cell contracts; a description of the project, project status, and key results to date is included. (WHK)

Synergistic Extraction of Copper from Nitrate Solutions Using β-Hydroxy-Naphthaldoxime and Organophosphorus Compounds into Carbon-Tetrachloride

Science.gov (United States)

Dey, Pulak; Basu, Sukalyan

2011-12-01

The extraction behavior of Cu(II) from an aqueous nitrate medium employing β-hydroxy-naphthaldoxime in carbon tetrachloride has been investigated in the presence of several organophosphorus donors like tri-octyl phosphine oxide, tri-butyl phosphine oxide, and tri-butyl phosphate at pH 1.5. The concentration of the metal was measured by atomic absorption spectrophotometry. Synergism was observed when neutral donor was added because of the formation of the adduct [Cu(L)2.(S)] in CCl4 (S denotes neutral donor). The equilibrium constants of the binary system using β-hydroxy-naphthaldoxime and the ternary system involving another addition of an organophosphorus compound were calculated from the extraction date obtained. Furthermore, the temperature dependence of the equilibrium constants was also investigated to evaluate standard enthalpy (Δ H°), entropy (Δ S°), and free energy (Δ G°) of the reactions proposed.

Social status of rural women in the focus of a developmental project

Directory of Open Access Journals (Sweden)

Stjepanović-Zaharijevski Dragana

2006-01-01

Full Text Available One of the goals of the project called "The milky river", which deals with the integral development of the dairy production, is to initiate the development of the sustainable and profitable production of milk and dairy products through grouping producers and supporting their position in the society they live in. Women are more than men engaged in the dairy production chain and they have a direct view of the whole dairy production process. So it was necessary to adapt the grouping to their needs, as well as to make some practical mechanisms of their involvement in the project activities. In this way, the strategy of the project helped with offering equal chances to women and men, and by reducing the gender inequality, it also helped with making a chance for a new life perspective for women. Through interviews and by focus-grouping the data were collected which represented the first picture of the dairy production in the region of Niš, including its gender characteristics, among other things. Two years later, the qualitative analysis of the indicators of the rural women’s social status in this region in the context of the realization of the project activities, has shown that there has been an important movement forward towards the gender equality which can be attributed to the successful project implementation. Women, as an important factor in the dairy production chain, seem to be joined and encouraged. They seem to be empowered at the level of their knowledge decision making and autonomous activity taking through various forms of education, joint farmer group work, as well as through various forms of cooperation with supporting institutions and other partners within the project activity framework. The overwhelming impression seems to be that joint work and cooperation are necessary conditions for the development of any individual farmers’ production, as well as for the referent rural development which requires the support of all the

Defense Standardization Program Status of Standardization Projects

Science.gov (United States)

1993-09-30

11352 AT Fl 902 903 903 A AT N C 25GP TOTAL - I , DELINQUENT - 1 , STATUS CODES: A - 1 , G - 0 , Y - 0 , Z - 0 2610 F158 TRA-YB TIRE & RIM ASSOCIATION...MECHANICAL SH H5 923 924 924 A SH N C3950 N047 MIL-L-29250B LOADING JACK SYSTEM ISO CON YDV 02 932 943 943 A N 3950 TOTAL - 9 ,DELINQUENT - 5 ,STATUS CODES...SECURITY LABEL DC B4 BP 931 951 951 A SC OM 90 NS N DCPS 0012 INCORPORATE SONS PROTOCOLS INTO OSI ol B4 BP 932 954 954 A SC OM 90 NS N DCPS 0012 02 ISO

Shark Cartilage Attenuates Oxidative Stress in the liver of Guinea Pigs Exposed to Carbon Tetrachloride and/or Gamma Irradiation

International Nuclear Information System (INIS)

Ibrahim, N.K.; Abd El Aziz, N.

2009-01-01

There is overwhelming evidence to indicate that oxidative stress is involved in the pathogenesis of several diseases. Carbon tetrachloride (CCl 4 ) and ionizing radiations are environmental pollutants well known to induce free radicals formation and oxidative stress. The objective of this work was to evaluate the effect of shark cartilage administration on CCl 4 and/or gamma radiation-induced oxidative damage in the liver. CCl 4 (1 ml/kg body wt) was subcutaneously administered to guinea pigs twice a week for four weeks. Gamma irradiation (RAD) was applied by whole body exposure of guinea pigs to 1.0 Gy/week up to a total dose of 4.0 Gy. Shark cartilage (ShC) was given to animals at a concentration of 1.0 g/kg body wt daily, one week before exposure to CCl 4 and/or gamma irradiation and during the experimental period. Animals sacrificed at the end of the experimental period showed that administration of shark cartilage has significantly attenuated the increase in liver malonaldehyde (MDA) observed in CCl 4 and/or irradiated guinea pigs. Furthermore, shark cartilage treatment has significantly increased the activity of antioxidant enzymes: superoxide dismutase (SOD) and catalase (CAT) and the content of reduced glutathione (GSH). The amelioration of oxidative stress induced in liver tissues of CCL 4 and/or irradiated guinea pigs treated with shark cartilage was associated with significant improvement in the activity of serum alanine amino transferase (ALT), aspartate amino transferase (AST), alkaline phosphatase (ALP), as well as, bilirubin, albumin, and iron contents. It could be concluded that shark cartilage might protect liver tissues from oxidative injury induced by environmental pro-oxidants pollutants via modulating the antioxidant status and decreasing the process of lipid peroxidation

Evaluation of conducting a screening assessment of nutritional status of hospitalized patients. Presentation of main goals and objectives of the global health project "NutritionDay".

Science.gov (United States)

Jeznach-Steinhagen, Anna; Ostrowska, Joanna; Czerwonogrodzka-Senczyna, Aneta

2016-01-01

European Society for Clinical Nutrition and Metabolism (ESPEN) commenced in 2004 a global health project named "NutritionDay" aiming to promote awareness of proper nutritional status of hospitalized patients and to draw attention to the need for early detection of malnutrition among patients. Under the Polish law--pursunat to the regulation of the Minister of Health dated September 15, 2011 (amendment as of 27.12.2013)--a nutritional status of each patient should be assessed at the time of a hospital admission. of this study was to analyze the fulfilment of the mandatory questionnaire assessment of nutritional status at selected wards of one of Warsaw's clinical hospitals. The study included an analysis of medical records of patients hospitalized within 6 months (n = 26375). The correct fulfilment of screening questionnaire assessing nutritional status (NRS 2002 survey) and the information about patients' body weight as well as the results assessment of nutritional status were subject to the analysis. NRS 2002 questionnaire was present in only 67,14% medical records of patients, however 49.24% of them were unfilled. The obtained results confirming low degree of NRS 2002 questionnaires' fulfilment in one of the Warsaw clinical hospitals draws attention to the need for education of hospital personnel in the field of significance of screening of nutritional assessment and its regulations. The "NutritionDay" project is an interesting form to attract attention of the aforementioned problem and its global extent additionally encourage medical units to participate in the project.

Licensing Status of New and Expanding In-Situ Recovery Uranium Projects in the United States

Energy Technology Data Exchange (ETDEWEB)

Catchpole, G.; Thomas, M., E-mail: gccatchpole@uranerz.com [Uranerz Energy Corporation (URZ), Casper, WY (United States)

2014-05-15

The authors investigated the licensing status of new in-situ recovery (“ISR”) uranium projects, as well as the expansion of existing projects, within the United States (“US”). Specific emphasis and analysis is placed on those projects within the states of Texas and Wyoming. Of note, information used to prepare this paper was obtained from public sources that included company web sites, the US Securities and Exchange Commission, the US Nuclear Regulatory Commission (“NRC”), the US Energy Information Agency (“EIA”), and the relevant state regulatory agencies. The renewed interest in the production of natural uranium has been motivated, in part, by the increased sale price of yellowcake beginning around 2003 resulting in numerous new and existing natural resources companies acquiring mineral rights in the United States. Because of the economic favorability in terms of both operating and capital costs of ISR mines versus conventional mines in the US (with its relatively low grade of uranium ore), the model for most companies was to acquire mineral properties that had the potential for being mined using the ISR method. There were, however, exceptions to this model. The Uravan mineral district in southwest Colorado and southeast Utah, where relatively high-grade, shallow uranium deposits have the potential to be mined using underground methods, is one such exception. However, the focus of this paper will be on ISR projects. In Wyoming, which has been the top producer of natural uranium among the 50 states for the past seven years, there is one producing ISR mine (Bill Smith — Highland), one ISR mine on standby (Christensen Ranch), and two ISR uranium projects licensed but not yet built (Gas Hills and North Butte). Cameco Resources is planning to develop two ISR projects in Wyoming that have been licensed but not yet constructed. Additionally, three new uranium companies (Ur-Energy, Uranerz and Uranium One) have filed applications with the federal and

Competency model for the project managers of technical projects

Science.gov (United States)

Duncan, William R.

1992-05-01

Traditional job description techniques were developed to support compensation decisions for hourly wage earners in a manufacturing environment. Their resultant focus on activities performed on the job works well in this environment where the ability to perform the activity adequately is objectively verifiable by testing and observation. Although many organizations have adapted these techniques for salaried employees and service environments, the focus on activities performed has never been satisfactory. For example, stating that a project manager `prepares regular project status reports' tells us little about what to look for in a potential project manager or how to determine if a practicing project manager is ready for additional responsibilities. The concept of a `competency model' has been developed within the last decade to address this shortcoming. Competency models focus on what skills are needed to perform the tasks defined by the job description. For example, a project manager must be able to communicate well both orally and in writing in order to `prepare regular project status reports.'

Final status of the salt repository project waste package program experimental database

International Nuclear Information System (INIS)

Thornton, B.M.; Reimus, P.W.

1988-03-01

This report describes the final status of the Salt Repository Project Waste Package Program Experimental Database. The data base serves as a clearinghouse for all data collected within the Waste Package Program (WPP) and its predecessor programs at Pacific Northwest Laboratory (PNL). The database was maintained using RS/1 database management software. Documented assurance that the entries in the database were consistent with experimental records was provided by having each experimentalist inspect the entries and signify that they were in agreement with the records. The inspection and signoff were done per PNL technical procedures. Data for which it was impossible to obtain the experimentalist's inspection and signature were segregated from the rest of the database, although they could still be accessed by WPP staff. The WPPED contains two groups of subdirectories. One group contains data taken prior to the installation of quality assurance procedures at PNL. The other group of subdirectories contains data taken under the NQA-1 procedures since their installation in April 1985. As part of closeout activities in the Salt Repository Project, the WPP database has been archived onto magnetic media. The data in the database are available by request on magnetic media or in hardcopy form. 2 refs

Coordinators' experience-self evaluation of project development status

International Nuclear Information System (INIS)

Sijali, I.V

2009-01-01

Outlines the progress of the project as follows, design cleared ny NLO, PMO and team refined the submitted project design to improve it's quality. Comments and any questions invited deadline 23 may 2008, endorsement of the project by Tuesday 24 June 2008 and project completed

Developing European conservation and mitigation tools for pollination services: approaches of the STEP (Status and Trends of European Pollinators) project

NARCIS (Netherlands)

Potts, S.G.; Biesmeijer, J.C.; Bommarco, R.; Felicioli, A.; Fischer, M.; Jokinen, P.; Kleijn, D.; Klein, A.M.; Kunin, W.E.; Neumann, P.; Penev, L.D.; Petanidou, T.; Rasmont, P.; Roberts, S.P.M.; Smith, H.G.; Sorensen, P.B.; Steffan-Dewenter, I.; Vaissiere, B.E.; Vila, M.; Vujic, A.; Woyciechowski, M.; Zobel, M.; Settele, J.; Schweiger, O.

2011-01-01

Pollinating insects form a key component of European biodiversity, and provide a vital ecosystem service to crops and wild plants. There is growing evidence of declines in both wild and domesticated pollinators, and parallel declines in plants relying upon them. The STEP project (Status and Trends

Ion projection lithography: November 2000 status and sub-70-nm prospects

Science.gov (United States)

Kaesmaier, Rainer; Wolter, Andreas; Loeschner, Hans; Schunck, Stefan

2000-10-01

Among all next generation lithography (NGL) options Ion Projection Lithography (IPL) offers the smallest (particle) wavelength of 5x10- 5nm (l00keV Helium ions). Thus, 4x reduction ion-optics has diffraction limits IOS) has been realized and assembled. In parallel to the PDT-IOS effort, at Leica Jena a test bench for a vertical vacuum 300mm-wafer stage has been realized. Operation of magnetic bearing supported stage movement has already been demonstrated. As ASML vacuum compatible optical wafer alignment system, with 3nm(3(sigma) ) precision demonstrated in air, has been integrated to this wafer test bench system recently. Parallel to the IPL tool development, Infineon Technologies Mask House and the Institute for Microelectronics Stuttgart are intensively working on the development of IPL stencil masks with success in producing 150mm and 200mm stencil masks as reported elsewhere. This paper is focused on information about the status of the PDT-IOS tool.

Fermented Citrus Lemon Reduces Liver Injury Induced by Carbon Tetrachloride in Rats

Directory of Open Access Journals (Sweden)

Yi Jinn Lillian Chen

2018-01-01

Full Text Available Fermented lemon juice displays a variety of important biological activities, including anti-inflammatory and antioxidant capabilities. The aim of the present study is to investigate hepatic-protective effects of no-sugar-added fermented lemon juice (FLJ for liver inflammation caused by carbon tetrachloride (CCl4 in rats. Rats are divided into six groups: H2O, CCl4 + H2O, CCl4 + silymarin, and CCl4 plus three different FLJ doses by oral administration, respectively. The results show that the contents of plasma ALT and AST, hepatic lipid peroxidation, splenomegaly, and liver water are reduced significantly in rats under FLJ treatment, and pathological examination of liver fibrosis is improved. The reduced hepatic injury by increasing liver soluble protein and glutathione and albumin is observed in FLJ treated groups, and FLJ has comparable efficacies to medicine silymarin in liver therapies. The no-sugar-added FLJ differs from traditional fermentation by adding lots of sugar and prevents any hidden sugar intake while taking it as a complimentary treatment for liver inflammation. The green color and the taste of sourness are both associated with treating and healing the liver based on the five-element theory in traditional Chinese medicine, and the green and sour FLJ may be applied to the ancient theory in preventing hepatic injury accordingly.

Further details concerning the radiolysis of a carbon tetrachloride-benzene mixture (1961); Complements a l'etude de la radiolyse du melange tetrachlorure de carbone-benzene (1961)

Energy Technology Data Exchange (ETDEWEB)

May, S [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires; Gislon-Leray, N [Faculte des Sciences de Paris, 75 (France)

1961-07-01

The neutron-activation estimation of the chlorine fixed on DPPH during radiolysis of the mixture C{sub 6}H{sub 6}-CCl{sub 4} makes it possible to evaluate the contribution of the carbon tetrachloride to the overall phenomenon. (authors) [French] Le dosage par activation neutronique du chlore fixe sur le DPPH lors de la radiolyse du melange C{sub 6}H{sub 6}-CCl{sub 4} permet d'evaluer la contribution du tetrachlorure de carbone au phenomene global. (auteurs)

Current status on advanced aqueous reprocessing process (next) in FaCT project

International Nuclear Information System (INIS)

Washiya, Tadahiro; Myochin, Munetaka; Koyama, Tomozo

2009-01-01

Japan Atomic Energy Agency (JAEA) launched the Fast Reactor Cycle Technology Development (FaCT) project in cooperation with the Japanese electric utilities in 2006. An integration of the advanced aqueous reprocessing concept and the simplified pelletizing fuel fabrication was selected as the most promising fuel cycle system. In order to accomplish the integration, R and D tasks were launched as FaCT Project in 2006 by Japanese joint team. The New Extraction System for TRU Recovery (NEXT) system is an advanced aqueous reprocessing concept which was based on the well established aqueous reprocessing for LWR spent fuel and newly applied processes such as uranium crystallization and extraction chromatography for MAs recovery. Main task of the NEXT process is to develop the TRU recovery process and equipments with high reliability, criticality safety, high durability and remote maintainability. In the FaCT project, all innovative technologies are planned to be developed within the next decade focusing on the future commercialization of FBR cycle systems. The judgment of the adoption of each innovative technology will be made by 2010 based on the results of R and Ds. The development of each technology is to be completed by around 2015. By the same time, it is scheduled to present the conceptual design of commercial and demonstrative fast reactor cycle facilities. The six items (Disassembling and shearing, Fuel dissolution, Uranium Crystallization, Single cycle co-extraction of U, Pu and Np, MA recovery by extraction chromatography and Waste treatment) have been identified as the issues to be developed corresponding to each process step. Current R and D status and prospects of this system until around 2015 is reported. (author)

Status of the mechanical design of the 650 MHz cavities for Project X

Energy Technology Data Exchange (ETDEWEB)

Barbanotti, S.; Grimm, C.; Champion, M.; Foley, M.; Ginsburg, C.M.; Gonin, I.; Peterson, T.; Ristori, L.; Yakovlev, V.; /Fermilab

2011-03-01

In the high-energy section of the Project X Linac, acceleration of H{sup -} ions takes place in superconducting cavities operating at 650 MHz. Two families of five-cell elliptical cavities are planned: beta = 0.61 and beta = 0.9. A specific feature of the Project X Linac is low beam loading, and thus, low bandwidth and higher sensitivity to microphonics. Efforts to optimize the mechanical design of the cavities to improve their mechanical stability in response to the helium bath pressure fluctuations will be presented. These efforts take into account constraints such as cost and ease of fabrication. Also discussed will be the overall design status of the cavities and their helium jackets. The proposed design of the 3 GeV Project X superconducting (SC) Linac employs 650 MHz five-cell elliptical cavities to accelerate 1.0 mA of average H-beam current in the 160-3000 MeV energy range. The 650 MHz region of the Linac is divided into two sections with two different geometric phase velocity factors: beta = 0.61 to cover the 160-520 MeV range and beta = 0.9 to cover the 520-3000 MeV range. Approximately 40 beta = 0.61 and 150 beta = 0.9 cavities are currently planned for the project. An R&D program is in progress at FNAL, in collaboration with TJNAF and India, to develop the 650 MHz cavities for the proposed Linac design. This R&D program includes the design and fabrication of several beta = 0.61 and beta = 0.9 single-cell prototypes for evaluation prior to production of the five-cell cavities. FNAL has contracted AES to fabricate the beta = 0.9 prototypes, while TJNAF is building beta = 0.61 prototypes of their own design. In the remainder of this paper we will restrict our discussion to the five-cell beta = 0.9 cavities.

Status of Project Management Education in Pakistan

Science.gov (United States)

Arain, Faisal Manzoor; Tipu, Syed Awais Ahmad

2009-01-01

Emerging contractual delivery systems, collaborative partnerships, new management initiatives, and global product markets require professionals and students to have a broader awareness of construction methods and project management issues. This paper presents the state of the project management education in Pakistan. The analysis is based on…

Evaluation of nuclear facility decommissioning projects. Status report. Humboldt Bay Power Plant Unit 3, SAFSTOR decommissioning

International Nuclear Information System (INIS)

Baumann, B.L.; Haffner, D.R.; Miller, R.L.; Scotti, K.S.

1986-06-01

This document explains the purpose of the US Nuclear Regulatory Commission's (NRC) Evaluation of Nuclear Facility Decommissioning Projects (ENFDP) program and summarizes information concerning the decommissioning of the Humboldt Bay Power Plant (HBPP) Unit 3 facility. Preparations to put this facility into a custodial safe storage (SAFSTOR) mode are currently scheduled for completion by June 30, 1986. This report gives the status of activities as of June 1985. A final summary report will be issued after completion of this SAFSTOR decommissioning activity. Information included in this status report has been collected from the facility decommissioning plan, environmental report, and other sources made available by the licensee. This data has been placed in a computerized data base system which permits data manipulation and summarization. A description of the computer reports that can be generated by the decommissioning data system (DDS) for Humboldt Bay and samples of those reports are included in this document

WBP/SIGAME the Brazilian BIG-GT demonstration project actual status and perspectives

International Nuclear Information System (INIS)

Carpentier, E.; Silva, A.

1998-01-01

Located in the tropics, with the sun shining all year round, and with its vast territory, Brazil may be regarded as having all the basic conditions to develop a modern Biomass for Electricity industry. Those characteristics together with: (a) the necessity of developing new energy resources for electricity production, in the northeast of the country; (b) the results of studies made by various entities, including CHESF; (c) the progress achieved by the BIG-GT technology; (d) the organisation of the Global Environment Facility (GEF); (e) and the support of the Brazilian government, through the Ministry of Science and Technology (MCT), provided the unique opportunity for the implementation of a commercial demonstration of that technology in Brazil. This paper describes the idea, scope, challenges, lessons, and actual status of development of the WBP/SIGAME project. It also highlights some institutional issues, budget figures, and energy prices. (author)

Synthesis of Novel E-2-Chlorovinyltellurium Compounds Based on the Stereospecific Anti-addition of Tellurium Tetrachloride to Acetylene

Directory of Open Access Journals (Sweden)

Svetlana V. Amosova

2012-05-01

Full Text Available The reaction of tellurium tetrachloride with acetylene proceeds in a stereospecific anti-addition manner to afford the novel products E-2-chlorovinyltellurium trichloride and E,E-bis(2-chlorovinyltellurium dichloride. Reaction conditions for the selective preparation of each of these products were found. The latter was obtained in 90% yield in CHCl₃ under a pressure of acetylene of 10–15 atm, whereas the former product was formed in up to 72% yield in CCl₄ under a pressure of acetylene of 1–3 atm. Synthesis of the previously unknown E,E-bis(2-chlorovinyl telluride, E,E-bis(2-chlorovinyl ditelluride, E-2-chlorovinyl 1,2,2-trichloroethyl telluride and E,E-bis(2-chlorovinyl-tellurium dibromide is described.

Project management. A discipline which contributes to project success

International Nuclear Information System (INIS)

Hoch, G.

2008-01-01

The presentation covers the following topics: description of the Project - a contract was signed between KNPP and European Consortium Kozloduy (ECK) consisting of Framatome ANP GmbH as Leader (63%), Framatome ANP S.A.S. (17%), Atomenergoexport (20%) ; Project management in the modernization of NPP Kozloduy units 5 and 6; Project management process within AREVA NP GmbH; current status

Metabolic activation of carbon tetrachloride by the cervico-vaginal epithelium in rodents

International Nuclear Information System (INIS)

Brittebo, E.B.; Brandt, I.

1989-01-01

The metabolism and binding of 14 C-labelled carbon tetrachloride (CCl 4 ) in the genital tract of female adult or juvenile NMRI-mice and Sprague-Dawly rats (mainly in the pro-oestrous/oestrous stage) and an adult New Zealand rabbit were studied. A marked irreversible binding of radioactivity in the squamous cervico-vaginal epithelium of mice given intravenous injections of 14 C-CCl 4 was revealed by autoradiography of solvent-extracted tissue. The localization of binding in the mouse genital tract incubated with 14 C-CCl 4 under air was similar to that observed in vivo. Bound radioactivity was also present in the cylindrical epithelium of the rabbit vagina incubated with 14 C-CCl 4 in vitro. For a comparison, no preferential binding of radiolabelled diethylstilbestrol or ethinylestradiol was observed in the mouse cervico-vaginal epithelium. The level of irreversible binding to PMSG-primed (pregnant mare's serum gonadotrophin) vaginal epithelial 100 x g supernatants of mice and rats incubated with 14 C-CCl 4 under air was low. Addition of the reducing agent dithionite to the incubations increased the binding in the vaginal epithelium 20-fold. In juvenile mice and rats injected with 14 C-CCl 4 , the levels of metabolites in the epithelium were low, whereas PMSG-primed juvenile rats contained a higher level of metabolites. The results show that the cervico-vaginal epithelium can metabolically activate CCl 4 to reactive metabolites and suggest that the metabolism is under endocrine control. (author)

Overview of ITER project. Objective, history, status of development, structure and its future

International Nuclear Information System (INIS)

Matsuda, S.

2003-01-01

The objective of ITER Project is to demonstrate the scientific and technological feasibility of fusion energy for peaceful use. To achieve this goal, the Conceptual Design Activities (CDA 1988-1990) and the Engineering Design Activities (EDA 1992-2001) were conducted by the joint effort of EU, Japan, RF and US under the auspices of IAEA. Engineering design has been developed consistently with plasma physics databases obtained by the world-wide magnetic fusion devices up to and during the EDA. Technology R and D including development, manufacturing and testing of scalable models of major components have been also conducted and ensured manufacturing and technical feasibility of ITER. Such technical readiness to start ITER construction urged formal government negotiation initially by Canada, EU, Japan and RF, and intense meetings have been held since November 2001. The US and China have joined since Feb. 2003. Four candidate sites have been proposed by Canada, EU and Japan for construction and have been evaluated. Once the agreement will be made, the construction takes about 10 years to complete, followed by the operation and exploitation phase lasting about 20 years. This paper gives an overview of ITER Project including its role in the long range fusion program, history, status of development, collaboration structure and its future program. (author)

TA 55 Reinvestment Project II Phase C Update Project Status May 23, 2017

Energy Technology Data Exchange (ETDEWEB)

Giordano, Anthony P. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2017-05-25

The TA-55 Reinvestment Project (TRP) II Phase C is a critical infrastructure project focused on improving safety and reliability of the Los Alamos National Laboratory (LANL) TA-55 Complex. The Project recapitalizes and revitalizes aging and obsolete facility and safety systems providing a sustainable nuclear facility for National Security Missions.

Design, operations, and maintenance of the soil vapor extraction systems for the 200 West Area Carbon Tetrachloride Expedited Response Action

International Nuclear Information System (INIS)

Tranbarger, R.K.

1996-05-01

This report provides the design, operating, and maintenance guidelines for the soil vapor extraction (SVE) systems implemented as part of the 200 West Area Carbon Tetrachloride ERA. Additionally, this document provides general information regarding the ERA, the SVE system design, and the general approach towards soil vapor extraction. The remaining content of this document includes the following: regulatory compliance; summary of vadose zone physical and containment characteristics; past and present SVE system designs and potential design upgrades; general design and monitoring considerations for the SVE systems; descriptions of the SVE system components and their respective functions; safety requirements; operation of the SVE systems including startup, surveillances, shutdown, GAC canister changeouts, and wellfield characterization; monitoring requirements; SVE optimization; and instrument calibrations, preventive maintenance, and spare parts and site inventory requirements

Status of Standardization Projects

Science.gov (United States)

1993-12-31

A5 B 942 943 943 ASM SA 69 D, 8115 056; ASTM D 5118 FABRICATION OF FIBERBOARD SM AS B 941 943 943 A SM SA 69 Di- N 8115 0562 ASTM D 5168 FAB AND...DR&E(AR)759 STANDARDIZATION PROJECTS REPORT - 1ST QTR FY 1994 PREPARING ACTIVITY LISTING PA AAPAA p BPP .A- G/ASA NC AC 21 RC G CSOL- Qý yqFyýFT7RL AL...941 943 943 A SM SA 69 DH N 8115 0562 ASTM D 5168 FAB AND CLOSURE TRIPLE WALL SM AS B 941 943 943 A SM SA 69 DH N 8125 0379 V’L-B-61000 BOTTLES

Status of the CLIO project

International Nuclear Information System (INIS)

Miyoki, S; Uchiyama, T; Yamamoto, K

2004-01-01

The CLIO project involves the Cryogenic Laser Interferometer Observatory (CLIO) detector complex for gravitational wave detection and the Kamioka Laser Interferometric Strainmeter for the acquisition of geophysical data. CLIO has been constructed to demonstrate the feasibility of a future project, the Large-scale Cryogenic Gravitational wave Telescope (LCGT). It will utilize the low seismic and stable environment of the Kamioka mine as well as sapphire mirrors and suspension fibres at low temperature to reduce thermal noise. We designed CLIO to have a noise level limited by the thermal noise of sapphire mirrors and sapphire suspension fibres, which vary from 3 x 10 -19 m Hz -1/2 at 300 K to 2 x 10 -20 m Hz -1/2 at 20 K around 100 Hz. The strainmeter has already succeeded in monitoring the Earth's tidal motion with a strain sensitivity of 2 x 10 -12 . The seismic noise veto between these same-scale interferometers is expected to provide an effective means of data selection for the gravitational wave signal analysis, and the ground motion data obtained by the strainmeter will help to maintain the stable operation of CLIO

Network, system, and status software enhancements for the autonomously managed electrical power system breadboard. Volume 1: Project summary

Science.gov (United States)

Mckee, James W.

1990-01-01

This volume (1 of 4) gives a summary of the original AMPS software system configuration, points out some of the problem areas in the original software design that this project is to address, and in the appendix collects all the bimonthly status reports. The purpose of AMPS is to provide a self reliant system to control the generation and distribution of power in the space station. The software in the AMPS breadboard can be divided into three levels: the operating environment software, the protocol software, and the station specific software. This project deals only with the operating environment software and the protocol software. The present station specific software will not change except as necessary to conform to new data formats.

The MEarth Project: Status Update and the Commissioning of a Brand New Telescope Array in the Southern Hemisphere

Science.gov (United States)

Berta-Thompson, Zachory K.; Irwin, Jonathan; Charbonneau, David; Newton, Elisabeth R.; Dittmann, Jason

2014-06-01

The MEarth Project is an ongoing all-sky survey for Earth-like planets transiting the closest, smallest M dwarfs. MEarth aims to find good targets for atmospheric characterization with JWST and the next generation of enormous ground-based telescopes. MEarth's yearly data releases, containing precise light curves of nearby mid-to-late M dwarfs, provide a unique window into the photometric variability of the stars that will forever be among the most interesting targets in the search for potentially habitable exoplanets. We present a status update on the MEarth Project, including a detailed map of the progress we’ve made so far with 8 telescopes in the Northern hemisphere and promising early results from our new installation of 8 more telescopes in the Southern hemisphere.

Cost/benefit analysis comparing ex situ treatment technologies for removing carbon tetrachloride from Hanford groundwater

International Nuclear Information System (INIS)

Truex, M.J.; Brown, D.R.; Elliott, D.B.

1993-05-01

Pacific Northwest Laboratory conducted a cost/benefit and performance analysis to compare ex situ technologies that can be used to destroy the carbon tetrachloride (CCl 4 ) in the ground water of Hanford's 200 West Area. The objective of this work was to provide a direct quantitative and qualitative comparison of competing technologies. The technologies examined included a biological system, the Thermochemical Environmental Energy System II (TEES II), and a UV/oxidation system. The factors examined included key system operation parameters, impact on inorganic contaminants in the ground water, and secondary waste production. The cost effectiveness of these destruction technologies was also compared to the cost for an air stripping/granular activated carbon (AS/GAC) system. While the AS/GAC system appeared to be more cost effective at many levels than the CCl 4 destruction technologies, the secondary waste produced by this system may lead to significant cost and/or regulatory problems. The factors with the greatest influence on cost for each destruction technology are as follows: nutrient requirements for both of the biological systems, electricity requirements and the type of unit operations for the TEES II process, and electricity requirements for UV/oxidation

Protection effect of piper betel leaf extract against carbon tetrachloride-induced liver fibrosis in rats.

Science.gov (United States)

Young, Shun-Chieh; Wang, Chau-Jong; Lin, Jing-Jing; Peng, Pei-Ling; Hsu, Jui-Ling; Chou, Fen-Pi

2007-01-01

Piper betel leaves (PBL) are used in Chinese folk medicine for the treatment of various disorders. PBL has the biological capabilities of detoxication, antioxidation, and antimutation. In this study, we evaluated the antihepatotoxic effect of PBL extract on the carbon tetrachloride (CCl(4))-induced liver injury in a rat model. Fibrosis and hepatic damage, as reveled by histology and the activities of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were induced in rats by an administration of CCl(4) (8%, 1 ml/kg body weight) thrice a week for 4 weeks. PBL extract significantly inhibited the elevated AST and ALT activities caused by CCl(4) intoxication. It also attenuated total glutathione S-transferase (GST) activity and GST alpha isoform activity, and on the other hand, enhanced superoxide dismutase (SOD) and catalase (CAT) activities. The histological examination showed the PBL extract protected liver from the damage induced by CCl(4) by decreasing alpha-smooth muscle actin (alpha-sma) expression, inducing active matrix metalloproteinase-2 (MMP2) expression though Ras/Erk pathway, and inhibiting TIMP2 level that consequently attenuated the fibrosis of liver. The data of this study support a chemopreventive potential of PBL against liver fibrosis.

Total Flavonoids from Mimosa Pudica Protects Carbon Tetrachloride -Induced Acute Liver Injury in Mice

Directory of Open Access Journals (Sweden)

Zhen-qin QIU

2015-03-01

Full Text Available Objective: To observe the protective effect of total flavonoids from Mimosa pudica on carbon tetrachloride (CCl4-induced acute liver injury in mice. Methods: CCl4-induced acute liver injury model in mice was established. The activity of ALT and AST, the content of serum albumin (Alb and total antioxidant capacity (T-AOC were determined. The content of malondiadehyde (MDA was measured and the activity of superoxide dismutase (SOD was determined. The histopathological changes of liver were observed.Results: Compared with CCl4 modle group, each dose group of total flavonouida from Mimosa pudica couldreduced the activity of ALT and AST in mice obviously (P＜0.01, indicating they had remarkably protective effect on CCl4-induced acute liver injury in mice. high and middle dose groups of total flavonouida from Mimosa pudica couldincrease the content of Alb in mice (P＜0.01. Each dose group of total flavonouida from Mimosa pudica could enhance the level of T-AOC (P＜0.01. each dose group of total flavonouida from Mimosa pudica could lower the content of liver homogenate MDA but enhance the activity of SOD in a dose-depended manner (P＜0.01. Conclusion: Total flavones from Mimosa Pudica have obvious protective effect on CCl4-induced acute liver injury in mice.

Hanford Site Groundwater Monitoring for Fiscal Year 2005

Energy Technology Data Exchange (ETDEWEB)

Hartman, Mary J.; Morasch, Launa F.; Webber, William D.

2006-02-28

This report is one of the major products and deliverables of the Groundwater Remediation and Closure Assessment Projects detailed work plan for FY 2006, and reflects the requirements of The Groundwater Performance Assessment Project Quality Assurance Plan (PNNL-15014). This report presents the results of groundwater and vadose zone monitoring and remediation for fiscal year 2005 on the U.S. Department of Energy's Hanford Site, Washington. The most extensive contaminant plumes in groundwater are tritium, iodine-129, and nitrate, which all had multiple sources and are very mobile in groundwater. The largest portions of these plumes are migrating from the central Hanford Site to the southeast, toward the Columbia River. Carbon tetrachloride and associated organic constituents form a relatively large plume beneath the west-central part of the Hanford Site. Hexavalent chromium is present in plumes beneath the reactor areas along the river and beneath the central part of the site. Strontium-90 exceeds standards beneath all but one of the reactor areas. Technetium-99 and uranium plumes exceeding standards are present in the 200 Areas. A uranium plume underlies the 300 Area. Minor contaminant plumes with concentrations greater than standards include carbon-14, cesium-137, cis-1,2-dichloroethene, cyanide, fluoride, plutonium, and trichloroethene. Monitoring for the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 is conducted in 11 groundwater operable units. The purpose of this monitoring is to define and track plumes and to monitor the effectiveness of interim remedial actions. Interim groundwater remediation in the 100 Areas continued with the goal of reducing the amount of chromium (100-K, 100-D, and 100-H) and strontium-90 (100-N) reaching the Columbia River. The objective of two interim remediation systems in the 200 West Area is to prevent the spread of carbon tetrachloride and technetium-99/uranium plumes. Resource Conservation and

General concept and present status of the AMS - project

International Nuclear Information System (INIS)

Stan-Sion, C.; Plostinaru, D.; Catana, L.; Radulescu, M.; Marinescu, L.; Dima, R.

1998-01-01

The Institute of Nuclear Physics and Engineering, IFIN-HH, Bucharest started in 1996 the Construction Project for an AMS facility in Bucharest. The Project is supported by the German-Romanian scientific cooperation project RUM-013-97. In the frame of this project, scientific research, construction activities of electronic and mechanical devices and activities for calibration and optimization were performed. The activities in this year are concentrated on experimental tests and optimization of the AMS analysis procedure and on improving the tandem acceleration and transmission capability. These are as follows: - construction and tests of a high current sputter source, with spherical ionizer and automatic many-sample changer. Experimental tests and measurements of emittance and beam profile; - construction of the Injector Platform; - construction and tests of a Bragg - charged particle detector; - calibration and optimization experiments of the AMS ensemble. The AMS facility is based on the 8 MV - FN tandem accelerator and has the following main components: the AMS ion injector, a Wien - velocity filter, a 60 angle bending magnet and the particle detection system. For heavy particle detection we constructed a Bragg ionization chamber. This should be used for standard AMS measurements. A specific part of the AMS facility represents the AMS injector deck. The main components are: the high current sputter source, the analyzing double focusing magnet, two optical systems, a four-slit beam defining system in front of the analyzing magnet and a four-slit aperture with remote controlled Faraday cup (for beam current integration of stable isotopes) after the magnet. Finally, the pre-acceleration tube (40 kV) connects the ensemble to the ground potential of the accelerator beam line. For AMS measurements, the sputter ion source is able to provide both high beam current and small beam emittance. These characteristics are necessary in order to achieve high analyzing

Motivation, description, and summary status of geomechanical and geochemical modeling studies in Task D of the International DECOVALEX-THMC Project

International Nuclear Information System (INIS)

Birkholzer, J.T.; Barr, D.; Rutqvist, J.; Sonnenthal, E.

2005-01-01

The DECOVALEX project is an international cooperative project initiated by SKI, the Swedish Nuclear Power Inspectorate, with participation of about 10 international organizations. The general goal of this project is to encourage multidisciplinary interactive and cooperative research on modeling coupled thermo-hydro-mechanical-chemical (THMC) processes in geologic formations in support of the performance assessment for underground storage of radioactive waste. One of the research tasks, initiated in 2004 by the U.S. Department of Energy (DOE), addresses the long-term impact of geomechanical and geochemical processes on the flow conditions near waste emplacement tunnels. Within this task, four international research teams conduct predictive analysis of the coupled processes in two generic repositories, using multiple approaches and different computer codes. Below, we give an overview of the research task and report its current status

IRIS project update: status of the design and licensing activities

International Nuclear Information System (INIS)

Petrovic, B.; Carelli, M.

2004-01-01

This paper presents an overview of the current status of the IRIS (International Reactor Innovative and Secure) project, focusing on the design and licensing activities. An update relative to the previous presentation at the 4th HND Conference is provided, highlighting some of the main accomplishments over the past two years. After successfully completing the conceptual design phase, IRIS is now finalizing the preliminary design as well. The pre-application licensing review with the U.S. NRC has been initiated in October of 2002. The safety-by-design approach and PRA-guided design open the possibility to aim for licensing not requiring off-site emergency response planning. Multiple single-unit and twin-unit site layouts have been developed within the ESP (Early Site Permit) program currently pursued by three U.S. power utilities. Desalination and district heating options have recently been added to the base design. Staggered construction schedules of multiple units may be applied to optimize cash-flow and minimize the required investment, making IRIS a financially attractive option, even for economies with limited investment capabilities. Because of its modularity, compatibility with smaller/medium grids, and enabling gradual build of new generating capacity matching the needs, IRIS has a large potential in the worldwide market.(author)

Amelioration of carbon tetrachloride-induced hepatic injury by emulsified Antrodia extract

Directory of Open Access Journals (Sweden)

Wei-Chih Chang

2018-03-01

Full Text Available Objective(s: Antrodia cinnamomea (AC is found with anti-inflammatory and immunomodulatory biological activities. In this study, we investigated the anti-hepatitis effect of the emulsified AC extract from RO water or supercritical fluid CO2 with ethanol co-solvent extract methods of AC preparations. Materials and Methods: Five groups of eight to ten weeks male rats with a count of ten for each group were studied to evaluate the protection of two kinds of AC extract from hepatic injury. Acute liver injury of rats was induced by injecting 40% carbon tetrachloride (CCl4 1 mg/kg intraperitoneally. Positive and negative control groups rats were perfused with CCl4 or isotonic saline, respectively. Experimental groups received oral administration once/day of AC preparations before CCl4 treatment: water AC extract (WAE group, or emulsified AC extract from supercritical fluid extraction (EAE group for 5 days, and sacrificed on the 6th day and the blood and liver samples were collected under chloral hydrate anesthesia. The anti-inflammatory, antioxidant markers, and relevant signaling pathways were measured (AST, ALT, ROS, IL-1, IL-6, NO, and COX-2, MAPKs, and caspase-3. Results: EAE at 50 mg/kg significantly decreased the serum AST, ALT, IL-1, IL-6, NO, and ROS levels. Both extracts reduced the activation of p-ERK in the liver samples, but EAE inhibited COX-2 and caspase-3 protein expression better than WAE. The EAE ameliorated CCl4-induced hepatic injury significantly; as compared with WAE and the positive control. Conclusion: The hepatoprotection of EAE could be attributed to the antioxidant and anti-inflammatory effects of Antrodia.

Present Status of the JENDL Project (May, 2013). WPEC Meeting, Paris, France, 23-24 May, 2013

International Nuclear Information System (INIS)

Fukahori, Tokio; Iwamoto, Osamu; Ishikawa, Makoto

2013-01-01

This paper briefly presents the present status of the Japanese JENDL Project: organization of Japanese Nuclear Data Committee (JNDC), a research committee for JAEA research activities; Nuclear Data Evaluation (JENDL-4.0 Updated Files and JENDL-4.0 Plus, benchmarking for fission reactor applications (criticality for thermal systems, adjusted library for fast systems), new evaluations, covariances, evaluation tools, fission products decay data file); other activities such as the 2012 Symposium on Nuclear Data at Kyoto University Research Reactor Institute, the initiation of conversation on Covariance Data with users, the celebration of the Golden Jubilee (since 1963) of JNDC

[Evaluation of the socioeconomic status in epidemiological surveys: hypotheses of research in the Brianza area MONICA project].

Science.gov (United States)

Cesana, G C; Ferrario, M; De Vito, G; Sega, R; Grieco, A

1995-01-01

Socio-economic status (SES) has been reported as a causative factor of increasing health inequalities in industrialized countries. The phenomenon has been particularly investigated for job related diseases, including cardiovascular disease and risk. The group of occupational medicine specialists in the world wide MONItoring program of CARdiovascular disease (WHO-MONICA Project) is now producing a number of hypotheses about the application of internationally defined criteria and tools for SES evaluation in the Italian area of the Project, Area Brianza. After a short review of some main conceptual and methodological problems, a proposal is presented of an SES index, derived from the pooled data of two population surveys carried out in this area. From a randomized sample of 3200 residents, 25-64 years old, stratified by sex and age decade, 1731 subjects, 594 females and 1137 males, employed at the time of the screening were extracted. Four variables were considered: age, education, occupational level and job-strain (according to the Karasek-Theorell model) by which each subject was classified in three levels--high, medium, low--of education and occupation, whose combination was used to obtain as many levels of socio-economic status. This a method of building an SES index is based on a sequence of approximations following two essential criteria: limitation of the variables to be surveyed, through standardized procedures; ability to identify the "low" SES category, presumably more at risk for disease.

Is Socio-Economic Status a Determinant of HIV-Related Stigma Attitudes in Zimbabwe? Findings from Project Accept.

Science.gov (United States)

Mateveke, Kudzanai; Singh, Basant; Chingono, Alfred; Sibanda, E; Machingura, Ian

2016-08-17

HIV related stigma and discrimination is a known barrier for HIV prevention and care. We aimed to assess the relationship between socio-economic status (SES) and HIV related stigma in Zimbabwe. This paper uses data from Project Accept , which examined the impact of community-based voluntary counseling and testing intervention on HIV incidence and stigma. Total of 2522 eligible participants responded to a psychometric assessment tool, which assessed HIV related stigma and discrimination attitudes on 4 point Likert scale. The tool measured three components of HIV-related stigma: shame, blame and social isolation, perceived discrimination, and equity. Participants' ownership of basic assets was used to assess the socio-economic status. Shame, blame and social isolation component of HIV related stigma was found to be significantly associated with medium [odds ratio (OR)=1.73, Pstigma and discrimination programs to be effective, they should take into account the socio-economic context of target population.

Full molecular dynamics simulations of liquid water and carbon tetrachloride for two-dimensional Raman spectroscopy in the frequency domain

Energy Technology Data Exchange (ETDEWEB)

Jo, Ju-Yeon, E-mail: ju8879@kuchem.kyoto-u.ac.jp; Ito, Hironobu, E-mail: h.ito@kuchem.kyoto-u.ac.jp; Tanimura, Yoshitaka, E-mail: tanimura@kuchem.kyoto-u.ac.jp

2016-12-20

Frequency-domain two-dimensional (2D) Raman signals, which are equivalent to coherent two-dimensional Raman scattering (COTRAS) signals, for liquid water and carbon tetrachloride were calculated using an equilibrium–nonequilibrium hybrid molecular dynamics (MD) simulation algorithm. An appropriate representation of the 2D Raman spectrum obtained from MD simulations provides an easy-to-understand depiction of structural and dynamical properties. We elucidate mechanisms governing the 2D signal profiles involving anharmonic mode–mode coupling and the nonlinearities of the polarizability for the intermolecular and intramolecular vibrational modes. The predicted signal profiles and intensities can be utilized to analyze recently developed single-beam 2D spectra, whose signals are generated from a coherently controlled pulse, allowing the single-beam measurement to be carried out more efficiently. Moreover, the MD simulation results allow us to visualize the molecular structure and dynamics by comparing the accurately calculated spectrum with experimental result.

Pulmonary retention and tissue distribution of 239Pu nitrate in F344 rats and syrian hamsters inhaling carbon tetrachloride

International Nuclear Information System (INIS)

Benson, J.M.; Barr, E.B.; Lundgren, D.L.; Nikula, K.J.

1994-01-01

Carbon tetrachloride (CCl 4 ) has been used extensively in the nuclear weapons industry, so it is possible that nuclear plant workers have been exposed to CCl 4 and plutonium compounds. Potential for future exposure exists during open-quotes cleanupclose quotes operations at weapon production sites such as the Hanford, Washington, and Rocky Flats, Colorado, facilities. The current Threshold Limit Value for CCl 4 is 5 ppm; however, concentrations of CCl 4 occurring in the nuclear weapons facilities over the past 40-50 y are unknown and may have exceeded this value. The pilot study described in this report is designed to determine whether subchronic inhalation of CCl 4 by CDF register (F-344)/CrlBR rats and Syrian golden hamsters, at concentrations expected to produce some histologic changes in liver, alters the hepatic retention and toxic effects of inhaled 239 Pu nitrate 239 Pu(NO 3 ) 4

We are (all) the champions: The effect of status in the implementation of innovations

NARCIS (Netherlands)

B. Szatmari (Balazs)

2016-01-01

markdownabstractThis thesis explores the effects of status in the implementation of innovations in three empirical papers which investigate both the positive and negative impact of status –status of either the project leader, the project group, or the organization. We argue that every project member

Dietary honey and ginseng protect against carbon tetrachloride-induced hepatonephrotoxicity in rats.

Science.gov (United States)

El Denshary, Ezzeldeen S; Al-Gahazali, Mohammad A; Mannaa, Fathia A; Salem, Hesham A; Hassan, Nabila S; Abdel-Wahhab, Mosaad A

2012-11-01

Liver diseases are amongst the most serious health problems in the world today and hepatocellular carcinoma is one of the world's deadliest cancers. The aim of the current study was to evaluate the protective effect of sider honey and/or Korean ginseng extract (KGE) against carbon tetrachloride (CCl(4))-induced hepato-nephrotoxicity in rat. Eighty male Sprague-Dawley (SD) rats were allocated into different groups and over a 4-week period, they orally received honey and/or KGE or were treated either with CCl(4) alone (100 mg/kg b.w) or with CCl(4) after a pretreatment period with honey, KGE or a combination of both. Clinical, clinico-pathological and histopathological evaluations were done and CCl(4)-treated groups were compared with rats receiving no treatment and with rats given honey, KGE or a combination of these substances. The results indicated that oral administration of CCl(4) induced severe hepatic and kidney injury associated with oxidative stress. The combined treatment with CCl(4) plus honey and/or KGE resulted in a significant improvement in all evaluated parameters. This improvement was prominent in the group receiving CCl(4) after combined pretreatment with honey and KGE. Animals receiving honey and/or KGE (without CCl(4)-treatment) were comparable to the control untreated group. It could be concluded that honey and KGE protect SD rats against the severe CCl(4)-induced hepatic and renal toxic effects. Our results suggest that the protective activity of honey and KGE may have been related to their antioxidant properties. Copyright © 2011 Elsevier GmbH. All rights reserved.

Status of the MCNPtrademark/LCStrademark merger project

International Nuclear Information System (INIS)

Hughes, H.G.; Adams, K.J.; Chadwick, M.B.; Comly, J.C.; Frankle, S.C.; Hendricks, J.S.; Little, R.C.; Prael, R.E.; Waters, L.S.; Young, P.G.

1998-01-01

The MCNPX code is now in limited release in a beta-test version. We provide a brief status report on the physics modules now in the code and of the enhanced capabilities to use new evaluated neutron data. We also present new benchmark calculations in which LAHET and MCNPX are compared with experimental results from the Japan Atomic Energy Research Institute

U1/U2 crib groundwater biological treatment demonstration project

International Nuclear Information System (INIS)

Koegler, S.S.; Brouns, T.M.; Heath, W.O.

1989-11-01

The primary objective of the biological treatment project is to develop and demonstrate a process for Hanford groundwater remediation. Biodenitrification using facultative anaerobic microorganisms is a promising technology for the simultaneous removal of nitrates and organics from contaminated aqueous streams. During FY 1988, a consortium of Hanford groundwater microorganisms was shown to degrade both nitrates and carbon tetrachloride (CC1 4 ). A pilot-scale treatment system was designed and constructed based on the results of laboratory-and-bench-scale testing. This report summarizes the results of biological groundwater treatment studies performed during FY 1989 at the pilot-scale. These tests were conducted using a simulated Hanford groundwater with a continuous stirred-tank bioreactor, and a fluidized-bed bioreactor that was added to the pilot-scale treatment system in FY 1989. The pilot-scale system demonstrated continuous degradation of nitrates and CC1 4 in a simulated groundwater. 4 refs., 7 figs., 1 tab

Development of organic sector. Status quo report Finland CoreOrganic Project HealthyGrowth: From niche to volume with integrity and trust. WP 2

OpenAIRE

Risku-Norja, Helmi

2013-01-01

Abstract. The present review on the development of the organic sector and on the status of the organic research in Finland has been compiled within the frame of the HealthyGrowth project. The numeric data are based on official statistics. The role of the government and the national goals and strategies were captured by analyzing about 20 relevant national policy documents. Regarding research, the focus was on the completed and on-going projects that deal with either policy, markets and consu...

Theoretical predictions of properties and volatility of chlorides and oxychlorides of group-4 elements. II. Adsorption of tetrachlorides and oxydichlorides of Zr, Hf, and Rf on neutral and modified surfaces

Science.gov (United States)

Pershina, V.; Borschevsky, A.; Iliaš, M.; Türler, A.

2014-08-01

With the aim to interpret results of gas-phase chromatography experiments on volatility of group-4 tetrachlorides and oxychlorides including those of Rf, adsorption enthalpies of these species on neutral, and modified quartz surfaces were estimated on the basis of relativistic, two-component Density Functional Theory calculations of MCl4, MOCl2, MCl6-, and MOCl42 with the use of adsorption models. Several mechanisms of adsorption were considered. In the case of physisorption of MCl4, the trend in the adsorption energy in the group should be Zr > Hf > Rf, so that the volatility should change in the opposite direction. The latter trend complies with the one in the sublimation enthalpies, ΔHsub, of the Zr and Hf tetrachlorides, i.e., Zr Hf > Rf, as defined by the complex formation energies. In the case of adsorption of MCl4 on a chlorinated quartz surface, formation of the MCl62- surface complexes can occur, so that the trend in the adsorption strength should be Zr ≤ Hf < Rf. All the predicted sequences, showing a smooth change of the adsorption energy in the group, are in disagreement with the reversed trend Zr ≈ Rf < Hf, observed in the "one-atom-at-a-time" gas-phase chromatography experiments. Thus, currently no theoretical explanation can be found for the experimental observations.

Evaluation of the health status of six volunteers from the Mars 500 project using pulse analysis.

Science.gov (United States)

Shi, Hong-Zhi; Fan, Quan-Chun; Gao, Jian-Yi; Liu, Jun-Lian; Bai, Gui-E; Mi, Tao; Zhao, Shuang; Liu, Yu; Xu, Dong; Guo, Zhi-Feng; Li, Yong-Zhi

2017-08-01

To comprehensively evaluate the health status of 6 volunteers from the Mars 500 Project through analyzing their pulse graphs and determining the changes in cardiovascular function, degree of fatigue and autonomic nervous function. Six volunteers were recruited; all were male aged 26-38 years (average 31.83±4.96 years). Characteristic parameters reflflecting the status of cardiovascular functions were extracted, which included left ventricular contraction, vascular elasticity and peripheral resistance. The degree of fatigue was determined depending on the difference between the calendar age and biological age, which was calculated through the analysis of blood pressure value and characteristic parameters. Based on the values of pulse height variation and pulse time variation on a 30-s pulse graph, autonomic nervous function was evaluated. All parameters examined were marked on an equilateral polygon to form an irregular polygon of the actual fifigure, then health status was evaluated based on the coverage area of the actual fifigure. The results demonstrated: (1) volunteers developed weakened pulse power, increased vascular tension and peripheral resistance, and slight decreased ventricular systolic function; (2) the degree of fatigue was basically mild or moderate; and (3) autonomic nervous function was excited but generally balanced. These volunteers were in the state of sub-health. According to Chinese medicine theories, such symptoms are mainly caused by the weakening of healthy qi, Gan (Liver) failing in free coursing, and disharmony between Gan and Wei (Stomach), which manifests as a weak and string-like pulse.

Integrated Data Base: Status and waste projections

International Nuclear Information System (INIS)

Klein, J.A.

1990-01-01

The Integrated Data Base (IDB) is the official US Department of Energy (DOE) data base for spent fuel and radioactive waste inventories and projections. DOE low-level waste (LLW) is just one of the many waste types that are documented with the IDB. Summary-level tables and figures are presented illustrating historical and projected volume changes of DOE LLW. This information is readily available through the annual IDB publication. Other presentation formats are also available to the DOE community through a request to the IDB Program. 4 refs., 6 figs., 5 tabs

Andrographis paniculata ameliorates carbon tetrachloride (CCl(4))-dependent hepatic damage and toxicity: diminution of oxidative stress.

Science.gov (United States)

Koh, Pei Hoon; Mokhtar, Ruzaidi Azli Mohd; Iqbal, Mohammad

2011-01-01

Andrographis paniculata (hempedu bumi) is a plant that possesses many medicinal values in treating several diseases and for health care maintenance. However, its hepatoprotective activity and mechanism of action have not been fully investigated. Therefore, this study aimed to evaluate the hepatoprotective effects of A. paniculata and its mechanism of action in rats. Carbon tetrachloride (CCl(4)) challenge of rats at a dose of 1.2 ml/kg body weight-induced oxidative stress in the liver. This was evidenced by augmentation in lipid peroxidation, which was accompanied by a decrease in the activities of antioxidant enzymes and depletion in the level of reduced glutathione (P paniculata (P paniculata to scavenge the 2,2-Diphenyl-2-picrylhydrazyl radical was determined through its EC(50) value. The EC(50) value of A. paniculata was 583.60 ± 4.25 µg/ml. In addition, A. paniculata was found to contain 65.37 ± 1.20 mg/g total phenolics expressed as gallic acid equivalent. From these studies, it is concluded that A. paniculata could be used as a hepatoprotective agent and possesses the potential to treat or prevent degenerative diseases where oxidative stress is implicated.

Protection of the Extracts of Lentinus edodes Mycelia against Carbon-Tetrachloride-Induced Hepatic Injury in Rats

Directory of Open Access Journals (Sweden)

Mei-Fen Chen

2012-01-01

Full Text Available Lentinus edodes is the medicinal macrofungus showing potential for therapeutic applications in infectious disorders including hepatitis. In an attempt to develop the agent for handling hepatic injury, we used the extracts of Lentinus edodes mycelia (LEM to screen the effect on hepatic injury in rats induced by carbon tetrachloride (CCl4. Intraperitoneal administration of CCl4 not only increased plasma glutamic oxaloacetic transaminase (GOT and glutamic pyruvic transaminase (GPT but also decreased hepatic superoxide dismutase (SOD and glutathione peroxidase (GPx levels in rats. Similar to the positive control silymarin, oral administration (three times daily of this product (LEM for 8 weeks significantly reduced plasma GOT and GPT. Also, the activities of antioxidant enzymes of SOD and GPx were elevated by LEM. in liver from CCl4-treated rats, indicating that mycelium can increase antioxidant-like activity. Moreover, the hepatic mRNA and protein levels of SOD and GPx were both markedly raised by LEM. The obtained results suggest that oral administration of the extracts of Lentinus edodes mycelia (LEM has the protective effect against CCl4-induced hepatic injury in rats, mainly due to an increase in antioxidant-like action.

Reductive Dechlorination of Carbon Tetrachloride by Soil With Ferrous and Bisulfide

Science.gov (United States)

Choi, K.; Lee, W.

2008-12-01

Batch and column experiments were conducted to investigate the effect of concentration of reductants, contact time to activate reductive capacity, and pH on reductive dechlorination by soil with Fe(II) and HS- in this study. Carbon tetrachloride (CT) was used as a representative target organic compound. Sorption kinetic and isotherm tests were performed to investigate the influence of adsorption on the soil surface. Target compound in the soil suspension reached sorption equilibrium in 4 hours and the type of isotherm was well fitted by a linear type isotherm. In batch experiment, kinetic rate constants for the reductive dechlorination of CT increased with increasing the concentration of the reductants (Fe(II) and HS-). However, Fe(II) was a much more effective reductant, producing higher k values than those of HS-. The contact time of one day for the soil with HS- and that of four hours with Fe(II) showed the highest reaction rates. Additionally, the rate constants increased with the increase of pH in soil suspension with Fe(II) (5.2~8) and HS- (8.3~10.3), respectively. In column experiment, the soil column with Fe(II) showed larger bed volumes (13.76) to reach a column breakthrough than that with HS- indicating the treatment of Fe(II) is more effective for the reductive dechlorination of CT. To enhance reductive capacity of soil column under an acidic condition, CaO addition to the column treated with Fe(II) showed better results for the reductive dechlorination of CT than that of HS-. Fe(II) showed better CT dechlorination than HS- in batch and column reactors therefore, it can be used as an effective reducing agent for the treatment of soil contaminated with chlorinated organic compounds.

Hepatoprotective role of Nicotiana plumbaginifolia Linn. against carbon tetrachloride-induced injuries.

Science.gov (United States)

Shah, Abdus Saboor; Khan, Rahmat Ali; Ahmed, Mushtaq; Muhammad, Nawshad

2016-02-01

Nicotiana plumbignifolia (Linn) is used as folk medicine in the treatment of liver dysfunction in Pakistan. The present study was designed to investigate the hepatoprotective role of N. plumbignifolia methanolice extract (NPME) against carbon tetrachloride (CCl4)-induced oxidative damage in liver of chicks. Methanolic extract of N. plumbignifolia was obtained and was further evaluated as a hepatoprotective agent against CCl4-induced oxidative damage in liver of chicks. For this study, 60-day-old 50 male chicks were divided into five groups. Chicks of group 1 (control) had free access to food and water. Group II received 1 mL/kg of CCl4 (30% in olive oil v/v) via the intraperitoneal route thrice a week for 4 weeks. Group III received 100 mg/kg body weight (b.w.) of silymarin via gavage after 48 h of CCl4 treatment, whereas group IV were given 200 mg/kg b.w. NPME after 48 h of CCl4 treatment. Hepatoprotective activity was assessed by measuring the activities of the antioxidant enzymes: catalase, peroxidase, superoxide dismutase, glutathione peroxidase, glutathione reductase, and lipid peroxidation (thiobarbituric acid reactive substances (TBARS)). Serum was analyzed for various biochemical parameters. The results revealed that CCl4 induced oxidative stress as evidenced by the significant decrease in the activity levels of antioxidant enzymes, while an increase in the levels of TBARS in liver samples is compared with the control group. Serum levels lactate dehydrogenase, triglycerides, total cholesterol, and low-density lipoprotein was elevated while reducing high-density lipoprotein compared to controls. Cotreatment of NPME treatment reversed these alterations, which seems likely that NPME can protect the liver tissues against CCl4-mediated oxidative damage. © The Author(s) 2013.

NGNP Project 2011 Status and Path Forward

Energy Technology Data Exchange (ETDEWEB)

L.E. Demick

2011-12-01

High Temperature Gas Reactor (HTGR) technology can play an important role in the United States’ energy future by extending the use of nuclear energy for non-electricity energy production missions as well as continuing to provide a considerable base load electric power generation capability. Extending nuclear energy into the industrial and transportation sectors through the co-production of process heat and electricity provides safe and reliable energy for these sectors in an environmentally responsible manner. The safety case for the modular HTGR provides a substantial improvement in nuclear plant safety for the protection of the public and the environment, and supports collocation of the HTGR with major industrial facilities. The NGNP Project at the Idaho National Laboratory has been working toward an objective of commercializing the HTGR technology under DOE direction since 2006. The Project is undergoing a quantum shift in direction and scope as a result of recent DOE decisions. This paper summarizes where the Project has been, where it is at the time of this writing and what is needed in future activities to commercialize HTGR technology.

Status and prospects of the FaCT project

International Nuclear Information System (INIS)

Nagaoki, Yoshihiro; Kikuchi, Shin; Ichimiya, Masakazu

2008-01-01

'Fast Reactor Cycle Technology Development (FaCT)' project has been conducted since 2006. In this project, design study and research and development (R and D) on innovative technologies for fast reactor (FR) cycle system are implemented in order to present the conceptual designs of commercial and demonstration facilities by 2015 and start operating demonstration fast reactor in 2025. The R and Ds has been stepped forward into the development stage to establish the realization of innovative technologies which bring excellent performance to fast reactor cycle system. The purpose of R and D by 2010 is to decide whether innovative technologies shall be adopted. So promoting R and D of FR, the project governance was organized. Furthermore, several possible R and D have been effectively carried out within the frameworks of international cooperation, such as Global Nuclear Energy Partnership (GNEP), Generation IV International Forum (GIF), and International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO). (author)

Long-term archives of land surface albedo products through the EUMETSAT/LSA-SAF and ECMWF/C3S projects: status and project development plan

Science.gov (United States)

Carrer, D.; Pinault, F.; Ceamanos, X.; Meurey, C.; Moparthy, S.; Swinnen, E.; Trigo, I.

2017-12-01

The two space programs of EUMETSAT (project CDOP3, LSA-SAF) and ECMWF (the Copernicus Climate Change Service; C3S_312a Lot9) provide (or will provide) added-value satellite products for the meteorological and environmental science communities, especially in the fields of climate modeling, environmental management, natural hazards management, and climate change detection. The EUMETSAT/LSA-SAF project started in 1999 with research and development activities. The Third Continuous Development and Operations Phase (CDOP-3) starts in March 2017 and will end in 2022. This project uses instruments on board European satellites that were, or will be, launched between 2004 and 2022. Unlike the LSA-SAF, the COPERNICUS/C3S_312a project has no NRT constraint. Its first phase started in november 2016. One of the major objective of the COPERNICUS/C3S_312a project is to harmonize datasets from various sensors in order to provide consistent and continuous ECV products from the 80's until now.Presently, the delivered operational products comprise several surface albedo products using data from various space missions (METEOSAT, NOAA, METOP, …). We present here the portfolio of the surface albedo products that are disseminated with an operational status. Their characteristics and accuracy are detailed here after. Also we will present the development plan to produce long-term re-analysis and to prepare the arrival of the next generation of satellite (MTG, EPS-SG, ...). This work will lead in 2018 to 40 years of products characterizing the albedo properties of the surface. These programs provide a great opportunity to monitor and identify human-induced climate change since consistent production of data sets is guaranteed until at least 2022.

Shippingport Station Decommissioning Project (SSDP): configuration control system and project activity controls

International Nuclear Information System (INIS)

Mullee, G.R.

1986-01-01

The SSDP has been using a Configuration Control system as a significant element in the management plan for the safe and effective performance of the project. The objective of the Configuration Control system is to control the physical plant configuration, system status, work schedules, status tracking, and day-to-day problem resolution. Prior to the Decommissioning Operations Contractor (DOC) assuming operational responsibility for the Shippingport Plant, an assessment was made of the status of the configuration of the systems and related documentation. Action was taken as required to match the operating procedures and system documentation with the actual physical condition of the plant. During the first stage of the project, planning was put in place for subsequent decommissioning activities. This planning included defining organizational responsibilities, completing the necessary project instructions and procedures, and doing the planning and scheduling for the subsequent decommissioning phase activities. Detailed instructions for the performance of the various decommissioning tasks were prepared. Prior to the start of any work on a given Activity Package, a Work Authorization is required. The Work Authorization form provides a complete checklist to ensure that all necessary prerequisites are completed. A computerized Communications Configuration Control Information system monitors status including information on system status, tag-outs, radiological work permits, etc. An ongoing effort is being directed toward maintaining operating instructions and system schematics, etc. current as the Plant configuration changes. The experience with the Configuration Control System to date has been favorable

Lisosan G, a powder of grain, does not interfere with the drug metabolizing enzymes and has a protective role on carbon tetrachloride-induced hepatotoxicity.

Science.gov (United States)

Longo, Vincenzo; Chirulli, Vera; Gervasi, Pier Giovanni; Nencioni, Simona; Pellegrini, Michela

2007-08-01

Lisosan G is a powder of grain registered as an alimentary integrator. The treatment of rats for 4 days with 0.5 g Lisosan G/kg had no effect on various drug metabolizing enzymes. Experiments in vitro showed that Lisosan G had radical scavenger activity. A confirmation of the antioxidative property of Lisosan G was also confirmed when it was administered in vivo to carbon tetrachloride (CCl(4))-intoxicated rats. The toxicity caused by CCl(4)-treatment of rats was restored to the control levels when the rats were given Lisosan G for 4 days before CCl(4). Lisosan G thus does not interfere with drug metabolizing system but has antioxidant properties and protects against CCl(4)-induced hepatotoxicity.

Dielectric properties of liquid systems: study of interactions in the systems carbon tetrachloride with benzene, toluene, and p-xylene

Directory of Open Access Journals (Sweden)

Adrián H. Buep

2014-12-01

Full Text Available Intermolecular associations in liquid systems of non-polar and slightly polar compounds were studied through excess molar volumes (VEM and excess dielectric properties (εE and n2ED for mixtures of carbon tetrachloride (CCl4 with benzene (C6H6, toluene (C6H5CH3, and p-xylene (p-(CH32C6H4. These excess properties were calculated from measurements of density (ρ, static permittivity (ε, and refractive index (nD over the whole range of concentrations at 298.15 K. The values of the excess dielectric properties for these mixtures were fitted in two different ways, one through least squares using the Redlich–Kister equation and the other using a model developed to explain deviations from ideality. The first fit was found to be descriptive while the second gave the equilibrium constant values for the interaction products actually formed in the mixtures and the respective electronic polarizabilities and dipole moments, indicating the existence of interaction products.

Medical Data Architecture Project Status

Science.gov (United States)

Krihak, M.; Middour, C.; Gurram, M.; Wolfe, S.; Marker, N.; Winther, S.; Ronzano, K.; Bolles, D.; Toscano, W.; Shaw, T.

2018-01-01

The Medical Data Architecture (MDA) project supports the Exploration Medical Capability (ExMC) risk to minimize or reduce the risk of adverse health outcomes and decrements in performance due to in-flight medical capabilities on human exploration missions. To mitigate this risk, the ExMC MDA project addresses the technical limitations identified in ExMC Gap Med 07: We do not have the capability to comprehensively process medically-relevant information to support medical operations during exploration missions. This gap identifies that the current in-flight medical data management includes a combination of data collection and distribution methods that are minimally integrated with on-board medical devices and systems. Furthermore, there are a variety of data sources and methods of data collection. For an exploration mission, the seamless management of such data will enable a more medically autonomous crew than the current paradigm. The medical system requirements are being developed in parallel with the exploration mission architecture and vehicle design. ExMC has recognized that in order to make informed decisions about a medical data architecture framework, current methods for medical data management must not only be understood, but an architecture must also be identified that provides the crew with actionable insight to medical conditions. This medical data architecture will provide the necessary functionality to address the challenges of executing a self-contained medical system that approaches crew health care delivery without assistance from ground support. Hence, the products supported by current prototype development will directly inform exploration medical system requirements.

The ANGSTREM project: present status and development activities

International Nuclear Information System (INIS)

Stepanov, V.S.; Legyuenko, S.K.; Grigoriev, O.G.; Gromov, B.F.; Dedul, A.V.; Leonchyk, M.P.; Pashkin, Yu.G.; Pankratov, D.V.; Chekunov, V.V.; Skorikov, D.E.

1998-01-01

The project ANGSTREM of a modular-transportable nuclear power-and-heating station with assured safety for remote areas is described. The station is based on fast nuclear reactor cooling by a lead-bismuth eutectic. The possible evolution of the project is mentioned in relation to possible new application - sea water desalination or refrigeration plants. (author)

The status of the LANSCE refurbishment project (LANSCE-R)

International Nuclear Information System (INIS)

Erickson, John Leonard; Jones, Kevin; Streve, Michael

2008-01-01

The Los Alamos Neutron Science Center (LANSCE) accelerator is an 800-MeV proton linac that drives user facilities for isotope production, proton radiography, ultra-cold neutrons, weapons neutron research and various sciences using neutron scattering. The LANSCE Refurbishment Project (LANSCE-R) is an ambitious project to refurbish key elements of the LANSCE accelerator that are becoming obsolete or nearing end-of-life. The conceptual design phase for the project is funded and underway. The 5 year, $170M (US) project will enable future decades of reliable, high-performance operation. It will replace a substantial fraction of the radio-frequency power systems (gridded tubes and klystrons) with modern systems, completely refurbish the original accelerator control and timing systems, replace obsolete diagnostic devices, and modernize other ancillary systems. An overview of the LANSCE-R project will be presented. The functional and operating requirements will be discussed, the proposed technical solutions presented, and the plan for successful project execution while meeting annual customer expectations for beam delivery will be reviewed.

Sustainable Energy (SUSEN) project

International Nuclear Information System (INIS)

Richter, Jiri

2012-01-01

Research Centre Rez and University of West Bohemia started preparatory work on the 'Sustainable Energy' project, financed from EU structural funds. The goals and expected results of the project, its organization, estimated costs, time schedule and current status are described. (orig.)

Web-based Project Reporting System

Data.gov (United States)

US Agency for International Development — Web-PRS is a web-based system that captures financial information and project status information that is sortable by geographical location, pillar, project type and...

Western Gas Sands Project status report

Energy Technology Data Exchange (ETDEWEB)

Atkinson, C.H.

1978-11-30

Progress of government-sponsored projects directed toward increasing gas production from the low-permeability gas sands of the western United States is summarized. A Technology Implementation Plan (TIP) meeting was held at the CER office in Las Vegas, Nevada, October 16--19 to initiate the implementation phase of the Enhanced Gas Recovery (EGR) working group activities. A WGSP Logging Program meeting was conducted on October 24, 1978, at CER offices to define the problems associated with logs in tight gas sands. CER personnel and the project manager attended a two-day course on the fundamentals of core and reservoir analysis in Denver, Colorado, and met with USGS personnel to discuss USGS work on the WGSP. A meeting was held to discuss a contract for coring a Twin Arrow well on the Douglas Creek Arch, Colorado. CER Corporation personnel attended the Geological Society of America Annual Meeting held in Toronto, Canada, October 23--27 and a Gas Stimulation Workshop at Sandia Laboratories in Albuquerque, New Mexico, October 11 and 12 to discuss recent mineback experiments conducted at the Nevada Test Site. Fiscal year 1979 projects initiated by USGS and the Energy Technology Centers and National Laboratories are progressing as scheduled. Mobil Research and Development Corporation fractured zone 8 of the F-31-13G well in Rio Blanco County, Colorado. Colorado Interstate Gas Company poured the concrete pad for the compresser expected to be delivered in December and were laying pipeline between the wells at month end. The Mitchell Energy well, Muse Duke No. 1 was flowing on test at a rate of 2,100 Mcfd and preparations proceeded to fracture the well on November 15 with approximately 1,000,000 gal of fluid and 3,000,000 lb of sand. Terra Tek completed laboratory analyses of cores taken from the Mitchell Energy well.

Status of PACMAN Project at CERN

CERN Document Server

Catalan-Lasheras, Nuria; Modena , Michele

2015-01-01

Though the Large Hadron Collider (LHC) at CERN is just at the start of a program expected to run for 20 additional years, CERN is studying the next generation of colliders, like the Compact Linear Collider (CLIC). This project proposes an electron-positron collider with a length close to 50 km and with a centre of mass energy of 3 TeV at the collision point. One of the main challenges is the sub-micrometric size of the beams, down to a few nanometres at the interaction point. As a consequence, the accelerator will require unprecedented nanometric tolerances of beam alignment. A series of several thousands components will have to be assembled, aligned at the micrometre level and most critically, stabilized actively at the nanometre level. PACMAN, a study on Particle Accelerator Components Metrology and Alignment to the Nanometre scale, is a Marie Curie Program supported by the European Commission (FP7 Program), creating a network of 16 Academic and Industrial Partners. The project is hosted at CERN and it offe...

The ANTARES project

International Nuclear Information System (INIS)

Amram, Ph.; Anvar, S.; Aslanides, E.; Aubert, J.J.; Azoulay, R.; Basa, S.; Benhammou, Y.; Bernard, F.; Berthier, R.; Bertin, V.; Billault, M.; Biller, S.; Blanc, F.; Blanc, P.E.; Bland, R.W.; Blondeau, F.; Botton, N. de; Bottu, N.; Boulesteix, J.; Brooks, B.; Brunner, J.; Calzas, A.; Carloganu, C.; Carr, J.; Carton, P.H.; Cartwright, S.; Cases, R.; Cassol, F.; Charles, F.; Charles, J.; Desages, F.; Destelle, J.J.; Dispau, G.; Duval, P.Y.; Engelen, J.; Feinstein, F.; Flores, E.C.; Fopma, J.; Fuda, J.L.; Goret, P.; Gosset, L.; Gournay, J.F.; Hernandez, J.J.; Hubaut, F.; Hubbard, R.; Huss, D.; Jaquet, M.; Jelley, N.; Kajfasz, E.; Kouchner, A.; Kudryavtsev, V.; Lachartre, D.; Lafoux, H.; Lamare, P.; Languillat, J.C.; Laugier, J.P.; Le Provost, H.; Loiseau, D.; Loucatos, S.; Magnier, P.; Marc, K.; Marcelin, M.; Martin, L.; Mazeau, B.; Mazure, A.; McMillan, J.; Meessen, C.; Millot, C.; Mols, P.; Montanet, F.; Moorhead, M.; Moscoso, L.; Navas, S.; Nooren, Van; Olivetto, C.; Palanque-Delabrouille, N.; Pallares, A.; Payre, P.; Perrin, P.; Poinsignon, J.; Potheau, R.; Qian, Z.; Raymond, M.; Roberts, J.; Sacquin, Y.; Schuller, J.P; Schuster, W.; Spooner, N.; Stolarczyk, T.; Tabary, A.; Talby, M; Tao, C.; Thompson, L.; Triay, R.; Valdy, M.; Velasco, J.; Vigeolas, E.; Vignaud, D.; Vilanova, D.; Wark, D.; Zuniga, J.

1999-01-01

The ANTARES project is an international collaboration with the aim of building a deep-sea large area neutrino telescope within the next decade. The achievements and status of the project as at the time of the conference are briefly discussed, and short term steps as well as longer term plans are described

A cientificidade das técnicas projetivas em debate The scientific status of projective techniques in discussion

Directory of Open Access Journals (Sweden)

Anna Elisa de Villemor-Amaral

2006-12-01

Full Text Available O objetivo deste trabalho é rever uma série especial de artigos antagônicos sobre a validade e o status científico dos métodos projetivos, uma vez que o foco dos debates atuais recai novamente sobre o mérito das técnicas projetivas em contraposição às objetivas, principalmente no que diz respeito ao pouco rigor metodológico nos estudos de validação e ausência de validade incremental, o que, conseqüentemente, repercute na credibilidade dos profissionais e pesquisadores que as utilizam. Neste artigo, dá-se destaque ao que há de procedente em tais discussões, bem como nas distorções ou falácias geradas nesta última década sobre os três procedimentos mais utilizados para avaliação da personalidade, no Brasil e exterior: o Método de Rorschach no Sistema Compreensivo, RCS; o Teste de Apercepção Temática, TAT e o Desenho da Figura Humana, DFH. Os referenciais apresentados sobre a utilidade clínica e diagnóstica desses instrumentos mostram-se igualmente úteis na ponderação de estudos e na discussão de questões relativas às técnicas projetivas de modo geral.The aim of this paper is to review and discuss a special series of antagonistic articles about the scientific status of the projective methods for personality assessment since the focus of the current debates has fallen again into the merit of the projectives in contraposition to the objective techniques. The critics are mainly in respect to the little methodologic procedures in the validation studies as well the absence of incremental validity for the projective methods, what consequently reverberates in the credibility of the professionals and researchers who use them. In this circumstances, this work emphasizes the positive aspects on the controversial as well the distortions or fallacies generated in this last decade about the three used procedures for personality assessment, in Brazil and exterior: the Method of Rorschach in the Comprehensive System, RCS

Study of lifetimes of fluorescence levels of tetravalent uranium in the incommensurate phase of thorium tetrabromide and tetrachloride

International Nuclear Information System (INIS)

Milicic, A.

1989-01-01

The lifetimes of radiative levels of tetravalent uranium in the incommensurate phase of thorium tetrahalides have been measured as a function of different parameters: site symmetry, temperature and concentration. The incommensurate phase of thorium tetrabromide and tetrachloride is characterized by a continuous distribution of site symmetries induced by a continuous and weak displacement of the halides around the thorium (uranium) ions. At low temperature, 4.2 K, the lifetime variation as a function of excited classes of symmetry is governed by the radiative process probability as well as the energy transfer between uranium ions in different sites. At higher temperature, a model based on a Boltzmann equilibrium between closed energy levels is able to reproduce the experimental lifetime variation as a function of the temperature, for a given class of symmetry. For the variation of lifetime as a function of uranium ion concentrations, at high dilution and in the case of U 4+ : ThBr 4 , there is a competition between the energy transfer and thermal population of excited states [fr

Hazardous materials in aquatic environments of the Mississippi River basin. Quarterly project status report, April 1, 1993--June 30, 1993

Energy Technology Data Exchange (ETDEWEB)

1993-08-01

During this quarter, the Review Panel made its final recommendations regarding which of the proposals should be funded. Included in this report is a brief status report of each of the research and education projects that are currently funded in this project. The Coordinated Instrumentation Facility (CIF) sponsored 3 seminars on Environmental Sample Preparation Techniques. These seminars were designed to educate the investigators on the use of microwave digestion systems for sample preparation and the use of Inductively Coupled Plasma and Atomic Absorption Specrtroscopy for analyses. During this period, Tulane and Xavier Universities have worked closely with Oak Ridge National Laboratories (ORNL) to develop a long term relationship that will encourage interaction and collaborations among the investigators at all of the institutions.

Status and understanding of groundwater quality in the Santa Clara River Valley, 2007-California GAMA Priority Basin Project

Science.gov (United States)

Burton, Carmen A.; Montrella, Joseph; Landon, Matthew K.; Belitz, Kenneth

2011-01-01

Groundwater quality in the approximately 460-square-mile Santa Clara River Valley study unit was investigated from April through June 2007 as part of the Priority Basin Project of the Groundwater Ambient Monitoring and Assessment (GAMA) Program. The GAMA Priority Basin Project is conducted by the U.S. Geological Survey (USGS) in collaboration with the California State Water Resources Control Board and the Lawrence Livermore National Laboratory. The Santa Clara River Valley study unit contains eight groundwater basins located in Ventura and Los Angeles Counties and is within the Transverse and Selected Peninsular Ranges hydrogeologic province. The Santa Clara River Valley study unit was designed to provide a spatially unbiased assessment of the quality of untreated (raw) groundwater in the primary aquifer system. The assessment is based on water-quality and ancillary data collected in 2007 by the USGS from 42 wells on a spatially distributed grid, and on water-quality data from the California Department of Public Health (CDPH) database. The primary aquifer system was defined as that part of the aquifer system corresponding to the perforation intervals of wells listed in the CDPH database for the Santa Clara River Valley study unit. The quality of groundwater in the primary aquifer system may differ from that in shallow or deep water-bearing zones; for example, shallow groundwater may be more vulnerable to surficial contamination. Eleven additional wells were sampled by the USGS to improve understanding of factors affecting water quality.The status assessment of the quality of the groundwater used data from samples analyzed for anthropogenic constituents, such as volatile organic compounds (VOCs) and pesticides, as well as naturally occurring inorganic constituents, such as major ions and trace elements. The status assessment is intended to characterize the quality of untreated groundwater resources in the primary aquifers of the Santa Clara River Valley study unit

The Imo State (Nigeria) Drinking Water Supply and Sanitation Project, 2. Impact on dracunculiasis, diarrhoea and nutritional status.

Science.gov (United States)

Huttly, S R; Blum, D; Kirkwood, B R; Emeh, R N; Okeke, N; Ajala, M; Smith, G S; Carson, D C; Dosunmu-Ogunbi, O; Feachem, R G

1990-01-01

Morbidity due to dracunculiasis (guinea worm disease) and diarrhoea in persons of all ages, and nutritional status of young children, were used as health impact indicators in the evaluation of the Imo State Drinking Water Supply and Sanitation Project in south-eastern Nigeria. Data were collected using repeated cross-sectional surveys and longitudinal follow-up. The study area was found to have a low level of endemicity of dracunculiasis. While no impact could be demonstrated on overall period or point prevalence rates in the cross-sectional surveys, a prospective longitudinal survey showed a significant reduction in the percentage of person-fortnights positive for dracunculiasis in areas served by the project, while the control areas showed no such change. In the cross-sectional surveys it was found that, in the project villages, those persons drinking only borehole water had significantly lower period prevalence rates one year later than others. Moreover, those living further from the nearest borehole had higher rates of dracunculiasis. An impact of the project on diarrhoea morbidity was found only in limited sub-groups of the population. A greater association with water availability rather than quality was suggested for rates in young children. The prevalence of wasting (less than 80% weight-for-height) among children aged less than 3 years decreased significantly over time in all 3 intervention villages; there was no such decline in the control villages.

Impact of low mini-mental status on health outcome up to 5 years after stroke: the Erlangen Stroke Project.

Science.gov (United States)

Liman, T G; Heuschmann, P U; Endres, M; Flöel, A; Schwab, S; Kolominsky-Rabas, P L

2012-06-01

Cognitive deficits are frequent stroke sequelae. Data from population-based stroke cohorts on the impact of cognitive deficits on long-term outcome are scarce. The purpose of this study was to investigate the impact of low mini-mental status on health outcome up to 5 years after first-ever stroke. Data were collected from the Erlangen Stroke Project, a population-based stroke registry covering a source population of 103,000 inhabitants. The Mini-Mental State Examination (MMSE) was used to assess global cognitive function. Health outcome included limitations in instrumental activities of daily living (IADL, Frenchay Activities Index), low independence in activities of daily living (ADL, Barthel Index), depressive symptoms (Zung Self Rating Depression Scale), and institutionalization. Using multivariate logistic regression analysis, association of an education-adjusted MMSE score ≤ 24 with these health outcomes was investigated within distinct models at 12, 36, and 60 months after stroke as well as predictors at 3 months for low IADL. A total of 705 patients with first-ever stroke were included. Institutionalization, low levels of ADL and IADL (p mini-mental status up to 3 years after stroke (OR 2.69, 95% CI 1.2-5.8) as well as older age (p mini-mental status has an independent impact on long-term health outcome after stroke. Our results emphasize the importance of cognitive status screening to identify stroke survivors at risk and manage and treat these patients more efficiently.

Status of readout integrated circuits for radiation detector

International Nuclear Information System (INIS)

Moon, B. S.; Hong, S. B.; Cheng, J. E. and others

2001-09-01

In this report, we describe the current status of readout integrated circuits developed for radiation detectors, along with new technologies being applied to this field. The current status of ASCIC chip development related to the readout electronics is also included in this report. Major sources of this report are from product catalogs and web sites of the related industries. In the field of semiconductor process technology in Korea, the current status of the multi-project wafer(MPW) of IDEC, the multi-project chip(MPC) of ISRC and other domestic semiconductor process industries is described. In the case of other countries, the status of the MPW of MOSIS in USA and the MPW of EUROPRACTICE in Europe is studied. This report also describes the technologies and products of readout integrated circuits of industries worldwide

Nigella sativa improves the carbon tetrachloride-induced lung damage in rats through repression of erk/akt pathway

Directory of Open Access Journals (Sweden)

Abdullah Aslan

2015-08-01

Full Text Available The objective of this study was to examine whether Nigella sativa plays a protective role against the damage in the lung by administering carbon tetra-chloride (CCl4 to rats. Male Wistar albino (n=28, 8 weeks old rats were divided into 4 groups: a negative control: Normal water consuming group to which no CCl4 and N. sativa was administered; b Positive control: Normal water consuming group to which no CCl4 was administered but N. sativa was administered; c CCl4 Group: Normal water consuming and group to which CCl4 was administered (1.5 mL/kg, ip; d N. sativa plus CCl4 group: CCl4 and N. sativa administered group (1.5 mL/kg, ip. Caspase-3, caspase -9, erk, akt protein syntheses were examined via Western blotting. Malondialdehyde determination in lung tissue was made using spectrophotometer. As a results, malondialdehyde amount was decreased in the CCl4 plus N. sativa group in comparison to CCl4 group whereas caspase-3, caspase-9 was increased and erk, akt had decreased. These results show that N. sativa protects the lung against oxidative damage.

Los Alamos National Laboratory Yucca Mountain Site Characterization Project 1992 quality program status report

International Nuclear Information System (INIS)

Bolivar, S.L.; Burningham, A.; Chavez, P.

1994-03-01

This status report summarizes the activities and accomplishments of the Los Alamos Yucca Mountain Site Characterization Project's quality assurance program for calendar year 1992. The report includes major sections on Program Activities and Trend Analysis. Program Activities are discussed periodically at quality meetings. The most significant issue addressed in 1992 has been the timely revision of quality administrative procedures. The procedure revision process was streamlined from 55 steps to 7. The number of forms in procedures was reduced by 38%, and the text reduced by 29%. This allowed revision in 1992 of almost half of all implementing procedures. The time necessary to complete the revision process (for a procedure) was reduced from 11 months to 3 months. Other accomplishments include the relaxation of unnecessarily strict training requirements, requiring quality assurance reviews only from affected organizations, and in general simplifying work processes. All members of the YMP received training to the new Orientation class Eleven other training classed were held. Investigators submitted 971 records to the Project and only 37 were rejected. The software program has 115 programs approved for quality-affecting work. The Project Office conducted 3 audits and 1 survey of Los Alamos activities. We conducted 14 audits and 4 surveys. Eight corrective action reports were closed, leaving only one open. Internally, 22 deficiencies were recognized. This is a decrease from 65 in 1991. Since each deficiency requires about 2 man weeks to resolve, the savings are significant. Problems with writing acceptable deficiency reports have essentially disappeared. Trend reports for 1992 were examined and are summarized herein. Three adverse trends have been closed; one remaining adverse trend will be closed when the affected procedures are revised. The number of deficiencies issued to Los Alamos compared to other participants is minimal

Reconnaissance survey for lightweight and carbon tetrachloride extractable hydrocarbons in the central and eastern basins of Lake Erie: September 1978

Energy Technology Data Exchange (ETDEWEB)

Zapotosky, J.E.; White, W.S.

1980-10-01

A reconnaissance survey of the central and eastern basins of Lake Erie (22,240 km/sup 2/) was conducted from September 17 to 27, 1978. The survey provided baseline information on natural gas and oil losses from geologic formations, prior to any potential development of natural gas resources beneath the United States portion of the Lake. Lightweight hydrocarbons indicative of natural gas (methane, ethane, propane, isobutane, and n-butane) are introduced into the waters of Lake Erie by escape from geologic formations and by biological/photochemical processes. The geochemical exploration technique of hydrocarbon sniffing provided enough data to reveal significant distribution patterns, approximate concentrations, and potential sources. Twelve sites with elevated lightweight hydrocarbon concentrations had a composition similar to natural gas. In one area of natural gas input, data analysis suggested a potential negative effect of natural gas on phytoplanktonic metabolism (i.e., ethylene concentration). Samples taken for liquid hydrocarbon analysis (carbon tetrachloride extractable hydrocarbons) correlated best with biologically derived lightweight hydrocarbons.

Richland Environmental Restoration Project management action process document

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-04-01

This document is the prescribed means for providing direct input to the US Department of Energy Headquarters regarding the status, accomplishments, strategy, and issues of the Richland Environmental Restoration Project. The project mission, organizational interfaces, and operational history of the Hanford Site are provided. Remediation strategies are analyzed in detail. The document includes a status of Richland Environmental Restoration project activities and accomplishments, and it presents current cost summaries, schedules, and technical baselines.

Richland Environmental Restoration Project management action process document

International Nuclear Information System (INIS)

1996-04-01

This document is the prescribed means for providing direct input to the US Department of Energy Headquarters regarding the status, accomplishments, strategy, and issues of the Richland Environmental Restoration Project. The project mission, organizational interfaces, and operational history of the Hanford Site are provided. Remediation strategies are analyzed in detail. The document includes a status of Richland Environmental Restoration project activities and accomplishments, and it presents current cost summaries, schedules, and technical baselines

The protective role of pomegranate juice against carbon tetrachloride-induced oxidative stress in rats.

Science.gov (United States)

Pirinççioğlu, Mihdiye; Kızıl, Göksel; Kızıl, Murat; Kanay, Zeki; Ketani, Aydın

2014-11-01

Most pomegranate (Punica granatum Linn., Punicaceae) fruit parts are known to possess enormous antioxidant activity. The present study was carried out to determine the phenolic and flavonoid contents of Derik pomegranate juice and determine its effect against carbon tetrachloride (CCl4)-induced toxicity in rats. Animals were divided into four groups (n = 6): group I: control, group II: CCl4 (1 ml/kg), group III: CCl4 + pomegranate juice and group IV: CCl4 + ursodeoxycholic acid (UDCA). Treatment duration was 4 weeks, and the dose of CCl4 was administered once a week to groups II, III and IV during the experimental period. CCl4-treated rats caused a significant increase in serum enzyme levels, such as aspartate aminotransferase, alanine aminotransferase and total bilirubin, and decrease in albumin, when compared with control. Administration of CCl4 along with pomegranate juice or UDCA significantly reduces these changes. Analysis of lipid peroxide (LPO) levels by thiobarbutiric acid reaction showed a significant increase in liver, kidney and brain tissues of CCl4-treated rats. However, both pomegranate juice and UDCA prevented the increase in LPO level. Histopathological reports also revealed that there is a regenerative activity in the liver and kidney cells. Derik pomegranate juice showed to be hepatoprotective against CCl4-induced hepatic injury. In conclusion, present study reveals a biological evidence that supports the use of pomegranate juice in the treatment of chemical-induced hepatotoxicity. © The Author(s) 2012.

Hepatocurative potential of sesquiterpene lactones of Taraxacum officinale on carbon tetrachloride induced liver toxicity in mice.

Science.gov (United States)

Mahesh, A; Jeyachandran, R; Cindrella, L; Thangadurai, D; Veerapur, V P; Muralidhara Rao, D

2010-06-01

The hepatocurative potential of ethanolic extract (ETO) and sesquiterpene lactones enriched fraction (SL) of Taraxacum officinale roots was evaluated against carbon tetrachloride (CCl 4 ) induced hepatotoxicity in mice. The diagnostic markers such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and total bilirubin contents were significantly elevated, whereas significant reduction in the level of reduced glutathione (GSH) and enhanced hepatic lipid peroxidation, liver weight and liver protein were observed in CCl 4 induced hepatotoxicity in mice. Post-treatment with ETO and SL significantly protected the hepatotoxicity as evident from the lower levels of hepatic enzyme markers, such as serum transaminase (ALT, AST), ALP and total bilirubin. Further, significant reduction in the liver weight and liver protein in drug-treated hepatotoxic mice and also reduced oxidative stress by increasing reduced glutathione content and decreasing lipid peroxidation level has been noticed. The histopathological evaluation of the liver also revealed that ETO and SL reduced the incidence of liver lesions induced by CCl 4 . The results indicate that sesquiterpene lactones have a protective effect against acute hepatotoxicity induced by the administration of CCl 4 in mice. Furthermore, observed activity of SL may be due to the synergistic action of two sesquiterpene lactones identified from enriched ethyl acetate fraction by HPLC method.

Hepatoprotective activity of Chhit-Chan-Than extract powder against carbon tetrachloride-induced liver injury in rats

Directory of Open Access Journals (Sweden)

Yi-Chun Lin

2014-06-01

Full Text Available The capability of Chhit-Chan-Than extract powder (CCTEP, 10% aqueous Ocimum gratissimum L. extract to protect against carbon tetrachloride (CCl4-induced oxidative stress and hepatotoxicity in vivo was investigated. Wistar rats were divided into five groups. Group A was a normal control group given only vehicle; Group B, the hepatotoxic group, was injected intraperitoneally twice a week with repeated 8% CCl4/olive oil (0.1 mL/100 g of body weight; Groups C–E, extract-treated groups received CCl4 and different doses of CCTEP (100 mg/kg and 200 mg/kg or silymarin (200 mg/kg of body weight daily by gavage for 8 weeks, respectively. The results showed that the CCl4-induced histopathogical changes may be prevented by CCTEP through reducing the intercellular collogen stack, dropping blood serum alanine aminotransferase and aspartate aminotransferase levels, and restoring the catalase activity and glutathione content. The hepatoprotective properties were further confirmed by the marked improvement in histopathological examination and by quantitative steatosis-fibrosis scoring. The above results suggest that CCTEP is able to prevent the liver inflammation and fibrosis induced by repeated CCl4 administration, and the hepatoprotective effects might be correlated partly with its antioxidant and free radical scavenging effects.

Possible Protective Effect of Kombucha Tea Ferment on Carbon Tetrachloride Induced Liver Damage in Irradiated Rats

International Nuclear Information System (INIS)

Gharib, O.A.; Fahim, Th.M.

2008-01-01

This study has shown that administration of kombucha ferment tea (KT) to rats improved the damage caused in livers of animals treated with toxic chemicals such as carbon tetrachloride (CCL 4 ) and/ or exposed to y-irradiation. This work was undertaken to evaluate the possible protective effects of treatment with KT ferment in rat liver after a long-term treatment with CCL 4 alone and with subsequent y-irradiation. Hepatic pathological changes observed in the CCL 4 -treated rats included increased serum alanine transaminase (ALT) , aspartate transaminase (AST), alkaline phosphatase (ALP) and gamma glutamyl transferase (GGT) activities as well as concentration of bilirubin in addition to a decrease in the concentration of serum albumin and total antioxidant capacity (TAC). Consistent with these changes, the increase in oxidative stress markers expressed as malondialdehyde (MDA) concentration and depletion in glutathione (GSH) contents in liver was observed. 24 h after the last dose of KT administration in a group of animals treated with CCL 4 and/ or radiation exposure cessation, the pathological changes were recovered. These results demonstrate that most of the pathological alterations in the liver in response to CCL 4 and/ or radiation exposure intoxication are recoverable upon treatment with KT ferments

Mutual diffusion of binary liquid mixtures containing methanol, ethanol, acetone, benzene, cyclohexane, toluene, and carbon tetrachloride

Energy Technology Data Exchange (ETDEWEB)

Guevara-Carrion, Gabriela; Janzen, Tatjana; Muñoz-Muñoz, Y. Mauricio; Vrabec, Jadran, E-mail: jadran.vrabec@uni-paderborn.de [Thermodynamics and Energy Technology, University of Paderborn, 33098 Paderborn (Germany)

2016-03-28

Mutual diffusion coefficients of all 20 binary liquid mixtures that can be formed out of methanol, ethanol, acetone, benzene, cyclohexane, toluene, and carbon tetrachloride without a miscibility gap are studied at ambient conditions of temperature and pressure in the entire composition range. The considered mixtures show a varying mixing behavior from almost ideal to strongly non-ideal. Predictive molecular dynamics simulations employing the Green-Kubo formalism are carried out. Radial distribution functions are analyzed to gain an understanding of the liquid structure influencing the diffusion processes. It is shown that cluster formation in mixtures containing one alcoholic component has a significant impact on the diffusion process. The estimation of the thermodynamic factor from experimental vapor-liquid equilibrium data is investigated, considering three excess Gibbs energy models, i.e., Wilson, NRTL, and UNIQUAC. It is found that the Wilson model yields the thermodynamic factor that best suits the simulation results for the prediction of the Fick diffusion coefficient. Four semi-empirical methods for the prediction of the self-diffusion coefficients and nine predictive equations for the Fick diffusion coefficient are assessed and it is found that methods based on local composition models are more reliable. Finally, the shear viscosity and thermal conductivity are predicted and in most cases favorably compared with experimental literature values.

Hepatoprotective potential of three sargassum species from Karachi coast against carbon tetrachloride and acetaminophen intoxication

Directory of Open Access Journals (Sweden)

Khan Hira

2016-01-01

Full Text Available Objective: To assess the hepatoprotective effect of ethanol extracts of Sargassum variegatum (S. variegatum, Sargassum tenerrimum (S. tenerrimum and Sargassum binderi occurring at Karachi coast against carbon tetrachloride (CCl4 and acetaminophen intoxication in rats. Methods: Sargassum species were collected at low tide from Buleji beach at Karachi coast. Effect of ethanol extracts of Sargassum spp., on lipid parameter, serum glucose and kidney function was examined. Liver damage in rats was induced by CCl4 or acetaminophen. Rats were administered with ethanol extracts of S. tenerrimum, S. variegatum and Sargassum binderi at 200 mg/kg body weight daily for 14 days separately. Hepatotoxicity was determined in terms of cardiac and liver enzymes and other biochemical parameters. Results: S. variegatum showed highest activity by reducing the elevated level of hepatic enzymes, bilirubin, serum glucose, triglyceride with restoration of cholesterol. Urea and creatinine concentrations were also significantly (P < 0.05 reduced as compared to acetaminophen intoxicated rats. S. tenerrimum and S. variegatum showed moderate activity against CCl4 hepatic toxicity. Conclusions: The protective role of S. variegatum against acetaminophen liver damage and its positive impact on disturbed lipid, glucose metabolism, kidney dysfunction and S. tenerrimum against CCl4 liver toxicity suggest that Sargassum species offer a non-chemical means for the treatment of toxicity mediated liver damage.

Environment and safety research status report: 1993

International Nuclear Information System (INIS)

1993-03-01

The 1993 status report discusses ongoing and planned research activities in the GRI Environment and Safety Program. The objectives and goals, accomplishments, and strategy along with the basis for each project area are presented for the supply, end use, and gas operations subprograms. Within the context of these subprograms, contract status summaries under their conceptual titles are given for the following project areas: Gas Supply Environmental and Safety Research, Air Quality Research, End Use Equipment Safety Research, Gas Operations Safety Research, Liquefied Natural Gas, Safety Research, and Gas Operations Environmental Research

Annual report for RCRA groundwater monitoring projects at Hanford Site facilities for 1995

International Nuclear Information System (INIS)

Hartman, M.J.

1996-02-01

This report presents the annual hydrogeologic evaluation of 19 Resource Conservation and Recovery Act of 1976 facilities and 1 nonhazardous waste facility at the US Department of Energy's Hanford Site. Although most of the facilities no longer receive dangerous waste, a few facilities continue to receive dangerous waste constituents for treatment, storage, or disposal. The 19 Resource Conservation and Recovery Act facilities comprise 29 waste management units. Nine of the units are monitored under groundwater quality assessment status because of elevated levels of contamination indicator parameters. The impact of those units on groundwater quality, if any, is being investigated. If dangerous waste or waste constituents have entered groundwater, their concentration profiles, rate, and extent of migration are evaluated. Groundwater is monitored at the other 20 units to detect leakage, should it occur. This report provides an interpretation of groundwater data collected at the waste management units between October 1994 and September 1995. Groundwater quality is described for the entire Hanford Site. Widespread contaminants include nitrate, chromium, carbon tetrachloride, tritium, and other radionuclides

Annual report for RCRA groundwater monitoring projects at Hanford site facilities for 1994

International Nuclear Information System (INIS)

1995-02-01

This report presents the annual hydrogeologic evaluation of 19 Resource Conservation and Recovery Act of 1976 facilities and 1 nonhazardous waste facility at the U.S. Department of Energy's Hanford Site. Although most of the facilities no longer receive dangerous waste, a few facilities continue to receive dangerous waste constituents for treatment, storage, or disposal. The 19 Resource Conservation and Recovery Act facilities comprise 29 waste management units. Nine of the units are monitored under groundwater quality assessment status because of elevated levels of contamination indicator parameters. The impact of those units on groundwater quality, if any, is being investigated. If dangerous waste or waste constituents have entered groundwater, their concentration profiles, rate, and extent of migration are evaluated. Groundwater is monitored at the other 20 units to detect leakage, should it occur. This report provides an interpretation of groundwater data collected at the waste management units between October 1993 and September 1994. Groundwater quality is described for the entire Hanford Site. Widespread contaminants include nitrate, chromium, carbon tetrachloride, tritium, and other radionuclides

Status of the CP-PACS Project

International Nuclear Information System (INIS)

Ukawa, A.

1995-01-01

The CP-PACS Project, which started in April 1992, is a five-year plan to develop a massively parallel computer for carrying out research in computational physics with primary emphasis on lattice QCD. This article describes the architectural design of the CP-PACS computer, the entire computing system including the front end and mass storage, and results of benchmarks for the expected performance for lattice QCD applications. ((orig.))

The CHEMVAL 2 project - status report

International Nuclear Information System (INIS)

Read, D.

1993-01-01

This paper summarizes the progress made during the first year of CHEMVAL 2, a coordinated four year research programme for evaluating and enhancing chemical models used in radiological risk assessment. Eighteen organisations from nine countries are currently participating, several of whom are also undertaking related experimental studies within the Commission of European Communities (CEC) MIRAGE Project (Migration of Radionuclides in the geosphere) - Third Phase. 16 refs., 3 figs

Tuberculosis Relief Belt Supporting Project (Tuberculosis Patient Management Project for Poverty Group).

Science.gov (United States)

Kim, Jae Kyoung; Jeong, Ina; Lee, Ji Yeon; Kim, Jung Hyun; Han, Ah Yeon; Kim, So Yeon; Joh, Joon Sung

2018-03-07

The "Tuberculosis Relief Belt Supporting Project (Tuberculosis Patient Management Project for Poverty Groups)" is a national program for socioeconomically vulnerable tuberculosis (TB) patients. We sought to evaluate the clinical and socioeconomic characteristics of poverty-stricken TB patients, and determined the need for relief. We examined in-patients with TB, who were supported by this project at the National Medical Center from 2014 to 2015. We retrospectively investigated the patients' socioeconomic status, clinical characteristics, and project expenditures. Fifty-eight patients were enrolled. Among 55 patients with known income status, 24 (43.6%) had no income. Most patients (80%) lived alone. A total of 48 patients (82.8%) had more than one underlying disease. More than half of the enrolled patients (30 patients, 51.7%) had smear-positive TB. Cavitary disease was found in 38 patients (65.5%). Among the 38 patients with known resistance status, 19 (50%) had drug-resistant TB. In terms of disease severity, 96.6% of the cases had moderate-to-severe disease. A total of 14 patients (26.4%) died during treatment. Nursing expenses were supported for 12 patients (20.7%), with patient transportation costs reimbursed for 35 patients (60%). In terms of treatment expenses for 31 people (53.4%), 93.5% of them were supported by uninsured benefits. Underlying disease, infectivity, drug resistance, severity, and death occurred frequently in socioeconomically vulnerable patients with TB. Many uninsured treatment costs were not supported by the current government TB programs, and the "Tuberculosis Relief Belt Supporting Project" compensated for these limitations. Copyright©2018. The Korean Academy of Tuberculosis and Respiratory Diseases.

Obeticholic acid protects against carbon tetrachloride-induced acute liver injury and inflammation

International Nuclear Information System (INIS)

Zhang, Da-Gang; Zhang, Cheng; Wang, Jun-Xian; Wang, Bi-Wei; Wang, Hua; Zhang, Zhi-Hui; Chen, Yuan-Hua; Lu, Yan; Tao, Li; Wang, Jian-Qing; Chen, Xi; Xu, De-Xiang

2017-01-01

The farnesoid X receptor (FXR) is a ligand-activated transcription factor that plays important roles in regulating bile acid homeostasis. The aim of the present study was to investigate the effects of obeticholic acid (OCA), a novel synthetic FXR agonist, carbon tetrachloride (CCl 4 )-induced acute liver injury. Mice were intraperitoneally injected with CCl 4 (0.15 ml/kg). In CCl 4 + OCA group, mice were orally with OCA (5 mg/kg) 48, 24 and 1 h before CCl 4 . As expected, hepatic FXR was activated by OCA. Interestingly, OCA pretreatment alleviated CCl 4 -induced elevation of serum ALT and hepatic necrosis. Moreover, OCA pretreatment inhibited CCl 4 -induced hepatocyte apoptosis. Additional experiment showed that OCA inhibits CCl 4 -induced hepatic chemokine gene Mcp-1, Mip-2 and Kc. Moreover, OCA inhibits CCl 4 -induced hepatic pro-inflammatory gene Tnf-α and Il-1β. By contrast, OCA pretreatment elevated hepatic anti-inflammatory gene Il-4. Further analysis showed that OCA pretreatment inhibited hepatic IκB phosphorylation and blocked nuclear translocation of NF-κB p65 and p50 subunits during CCl 4 -induced acute liver injury. In addition, OCA pretreatment inhibited hepatic Akt, ERK and p38 phosphorylation in CCl 4 -induced acute liver injury. These results suggest that OCA protects against CCl 4 -induced acute liver injury and inflammation. Synthetic FXR agonists may be effective antidotes for hepatic inflammation during acute liver injury. - Highlights: • OCA pretreatment activates hepatic FXR. • FXR activation protects against CCl 4 -induced acute liver injury. • FXR activation inhibits hepatocyte apoptosis during CCl 4 -induced liver injury. • FXR activation differentially regulates hepatic inflammatory genes. • Synthetic FXR agonists are effective antidotes for acute liver injury.

Obeticholic acid protects against carbon tetrachloride-induced acute liver injury and inflammation

Energy Technology Data Exchange (ETDEWEB)

Zhang, Da-Gang [First Affiliated Hospital, Anhui Medical University, Hefei 230022 (China); Zhang, Cheng [Department of Toxicology, Anhui Medical University, Hefei 230032 (China); Wang, Jun-Xian [First Affiliated Hospital, Anhui Medical University, Hefei 230022 (China); Wang, Bi-Wei; Wang, Hua; Zhang, Zhi-Hui; Chen, Yuan-Hua [Department of Toxicology, Anhui Medical University, Hefei 230032 (China); Lu, Yan; Tao, Li; Wang, Jian-Qing [Second Affiliated Hospital, Anhui Medical University, Hefei 230601 (China); Chen, Xi [First Affiliated Hospital, Anhui Medical University, Hefei 230022 (China); Xu, De-Xiang, E-mail: xudex@126.com [Department of Toxicology, Anhui Medical University, Hefei 230032 (China)

2017-01-01

The farnesoid X receptor (FXR) is a ligand-activated transcription factor that plays important roles in regulating bile acid homeostasis. The aim of the present study was to investigate the effects of obeticholic acid (OCA), a novel synthetic FXR agonist, carbon tetrachloride (CCl{sub 4})-induced acute liver injury. Mice were intraperitoneally injected with CCl{sub 4} (0.15 ml/kg). In CCl{sub 4} + OCA group, mice were orally with OCA (5 mg/kg) 48, 24 and 1 h before CCl{sub 4}. As expected, hepatic FXR was activated by OCA. Interestingly, OCA pretreatment alleviated CCl{sub 4}-induced elevation of serum ALT and hepatic necrosis. Moreover, OCA pretreatment inhibited CCl{sub 4}-induced hepatocyte apoptosis. Additional experiment showed that OCA inhibits CCl{sub 4}-induced hepatic chemokine gene Mcp-1, Mip-2 and Kc. Moreover, OCA inhibits CCl{sub 4}-induced hepatic pro-inflammatory gene Tnf-α and Il-1β. By contrast, OCA pretreatment elevated hepatic anti-inflammatory gene Il-4. Further analysis showed that OCA pretreatment inhibited hepatic IκB phosphorylation and blocked nuclear translocation of NF-κB p65 and p50 subunits during CCl{sub 4}-induced acute liver injury. In addition, OCA pretreatment inhibited hepatic Akt, ERK and p38 phosphorylation in CCl{sub 4}-induced acute liver injury. These results suggest that OCA protects against CCl{sub 4}-induced acute liver injury and inflammation. Synthetic FXR agonists may be effective antidotes for hepatic inflammation during acute liver injury. - Highlights: • OCA pretreatment activates hepatic FXR. • FXR activation protects against CCl{sub 4}-induced acute liver injury. • FXR activation inhibits hepatocyte apoptosis during CCl{sub 4}-induced liver injury. • FXR activation differentially regulates hepatic inflammatory genes. • Synthetic FXR agonists are effective antidotes for acute liver injury.

Is socio-economic status a determinant of HIV-related stigma attitudes in Zimbabwe? Findings from Project Accept

Directory of Open Access Journals (Sweden)

Kudzanai Mateveke

2016-08-01

Full Text Available HIV related stigma and discrimination is a known barrier for HIV prevention and care. We aimed to assess the relationship between socio-economic status (SES and HIV related stigma in Zimbabwe. This paper uses data from Project Accept, which examined the impact of community-based voluntary counseling and testing intervention on HIV incidence and stigma. Total of 2522 eligible participants responded to a psychometric assessment tool, which assessed HIV related stigma and discrimination attitudes on 4 point Likert scale. The tool measured three components of HIVrelated stigma: shame, blame and social isolation, perceived discrimination, and equity. Participants’ ownership of basic assets was used to assess the socio-economic status. Shame, blame and social isolation component of HIV related stigma was found to be significantly associated with medium [odds ratio (OR=1.73, P<0.01] and low SES (OR=1.97, P<0.01, indicating more stigmatizing attitudes by participants belonging to medium and low SES in comparison to high SES. For HIV related stigma and discrimination programs to be effective, they should take into account the socio-economic context of target population.

Projected entangled pair states: status and prospects

Energy Technology Data Exchange (ETDEWEB)

Verstraete, Frank [Universitaet Wien (Austria)

2008-07-01

We report on the progress made to extend the density matrix renormalization group to higher dimensions, discuss the underlying theory of projected entangled pair states (PEPS) and illustrate its potential on the hand of a few examples.

Taipower - latest projects to boost coal import levels

Energy Technology Data Exchange (ETDEWEB)

Hargreaves, D

1985-05-01

The activities are reviewd for Taipower, the state enterprise electrical power utility for Taiwan RC: its generating facilities and comparability; the status of major projects, especially the Taichung thermal project; the status of coal; coal burn performance; air pollution controls; coal ash performance; coal imports; transport logistics; including terminal facilities at the Taichung thermal power plant.

Solving the carbon tetrachloride (CCl4) budget mystery using surface observations

Science.gov (United States)

Liang, Q.; Newman, P. A.; Daniel, J. S.; Reimann, S.; Hall, B. D.; Dutton, G. S.; Kuijpers, L. J. M.

2014-12-01

Carbon tetrachloride (CCl4) is a major anthropogenic ozone-depleting substance, with an ozone depletion potential (with respect to CFC-11) of 0.82. CCl4 is also a greenhouse gas and the 100-yr global warming potential is 1,400. In 1987, the Montreal Protocol (MP) included CCl4, and production and consumption were phased out for developed countries in 1996. Developing countries were allowed a delayed reduction, but CCl4 was fully phased out from emissive uses in 2010. However, the near-zero 2007-2012 emissions estimate based on the UNEP reported production and feedstock usage cannot be reconciled with the observed slow decline of atmospheric concentrations, year-to-year variability, and the inter-hemispheric gradient (IHG). We use available source and sink data in the NASA 3-Dimensional (3-D) Chemistry Climate Model, GEOSCCM, to test existing emissions and lifetime estimates against CCl4 mixing ratio observations. Our model results show that the IHG and global trend provide useful information for quantitatively constraining CCl4 emissions and lifetime estimates. The observed IHG (1.5±0.2 ppt for 2000-2012) is primarily caused by ongoing current emissions, while ocean and soil losses and stratosphere-troposphere exchange together contribute a small negative gradient (~0 - -0.3 ppt). Using the observed CCl4 global trend and IHG from the National Oceanic and Atmospheric Administration - Global Monitoring Division (NOAA-GMD) and Advanced Global Atmospheric Gases Experiment (AGAGE) networks, we deduce the mean global emissions for the 2000-2012 period are 39 (34-45, lower-upper limit emission estimates) Gg/yr (~ 30% of the peak 1980s emissions) and a corresponding total lifetime of 35 (37-32, upper-lower limit lifetime estimates) years. These results point to the need for a more accurate bottom-up estimate of CCl4 emissions as well as re-evaluation of the CCl4 best estimate lifetime (currently 25 years).

Stevia Prevents Acute and Chronic Liver Injury Induced by Carbon Tetrachloride by Blocking Oxidative Stress through Nrf2 Upregulation

Science.gov (United States)

Ramos-Tovar, Erika; Hernández-Aquino, Erika; Casas-Grajales, Sael; Buendia-Montaño, Laura D.; Tsutsumi, Víctor

2018-01-01

The effect of stevia on liver cirrhosis has not been previously investigated. In the present study, the antioxidant and anti-inflammatory properties of stevia leaves were studied in male Wistar rats with carbon tetrachloride- (CCl4-) induced acute and chronic liver damage. Acute and chronic liver damage induced oxidative stress, necrosis, and cholestasis, which were significantly ameliorated by stevia. Chronic CCl4 treatment resulted in liver cirrhosis, as evidenced by nodules of hepatocytes surrounded by thick bands of collagen and distortion of the hepatic architecture, and stevia significantly prevented these alterations. Subsequently, the underlying mechanism of action of the plant was analyzed. Our study for the first time shows that stevia upregulated Nrf2, thereby counteracting oxidative stress, and prevented necrosis and cholestasis through modulation of the main proinflammatory cytokines via NF-κB inhibition. These multitarget mechanisms led to the prevention of experimental cirrhosis. Given the reasonable safety profile of stevia, our results indicated that it may be useful for the clinical treatment of acute and chronic liver diseases. PMID:29849889

Analysis of the Status and Impacts of NCTR Projects

Science.gov (United States)

2012-08-01

The National Center for Transit Research (NCTR) at the University of South Florida (USF) assessed the implementation status and identified the outcomes and impacts of the results of 30 Florida Department of Transportation -sponsored NCTR research pro...

Status of voluntary restraint

Energy Technology Data Exchange (ETDEWEB)

Aarts, W. [SWOKA Institute for Strategic Consumer Behaviour, Leiden (Netherlands)

2000-05-01

Do people enjoying a higher status, especially those with a higher education, constrain their consumption more than others? In general, higher status and high levels of consumption go hand in hand. But the greater availability of luxury goods has led to a decline in their exclusivity. Since environmental awareness has increased, a countercurrent may be possible. It is possible that certain high status groups, the environmentally aware trendsetters, can now be distinguished by their voluntary restraint rather than by their conspicuous consumption. This hypothesis formed the basis for a sociological doctoral project at the University of Amsterdam. The research was conducted under the umbrella of the National Research Programme on Global Air Pollution and Climate Change.

Topical report review status

International Nuclear Information System (INIS)

1982-08-01

A Topical Report Review Status is scheduled to be published semi-annually. The primary purpose of this document is to provide periodic progress reports of on-going topical report reviews, to identify those topical reports for which the Nuclear Regulatory Commission (NRC) staff review has been completed and, to the extent practicable, to provide NRC management with sufficient information regarding the conduct of the topical report program to permit taking whatever actions deemed necessary or appropriate. This document is also intended to be a source of information to NRC Licensing Project Managers and other NRC personnel regarding the status of topical reports which may be referenced in applications for which they have responsibility. This status report is published primarily for internal NRC use in managing the topical report program, but is also used by NRC to advise the industry of report review status

Topical report review status

International Nuclear Information System (INIS)

1983-01-01

A Topical Report Review Status is scheduled to be published semi-annually. The primary purpose of this document is to provide periodic progress reports of on-going topical report reviews, to identify those topical reports for which the Nuclear Regulatory Commission (NRC) staff review has been completed and, to the extent practicable, to provide NRC management with sufficient information regarding the conduct of the topical report program to permit taking whatever actions deemed necessary or appropriate. This document is also intended to be a source of information to NRC Licensing Project Managers and other NRC personnel regarding the status of topical reports which may be referenced in applications for which they have responsibility. This status report is published primarily for internal NRC use in managing the topical report program, but is also used by NRC to advise the industry of report review status

Fermilab ACP multi-microprocessor project

International Nuclear Information System (INIS)

Gaines, I.; Areti, H.; Biel, J.; Bracker, S.; Case, G.; Fischler, M.; Husby, D.; Nash, T.

1984-08-01

We report on the status of the Fermilab Advanced Computer Program's project to provide more cost-effective computing engines for the high energy physics community. The project will exploit the cheap, but powerful, commercial microprocessors now available by constructing modular multi-microprocessor systems. A working test bed system as well as plans for the next stages of the project are described

Hepatoprotective Potential of Propolis toward Hepar Injury Rats (Rattus norvegicus Induced by Carbon Tetrachloride

Directory of Open Access Journals (Sweden)

Diah Krisnansari

2016-09-01

Full Text Available Introduction: The prevalence of chronic liver disease continues to increase. One potentially hepatotoxic substances that cause chronic liver disease is carbon tetrachloride. The process of liver damage can be prevented by the antioxidant role of propolis. The aims of this research was to study the hepatoprotective potential of propolis toward hepar injury rats induced by carbon tetrachlorida. Method: This was an experimental study with pre-post test. Twenty five male Wistar rats aged 12–16 week old, weighing 125–200 gr were allocated into 5 groups. Group I: standard meal + aquadest-gavage; group II: standard meal + CCl4 1% 1 mL + aquadest-gavage, group III: standard meal + CCl4 1% 1 mL + 0,054 gr propolis-gavage, group IV: standard meal + CCl4 1% 1 mL + 0,108 gr propolis-gavage and group V: standard meal + CCl4 1% 1 mL + sylimarin 50 mg/kg-gavage. IL-6, SOD, NAS score+fibrotic were measured after treatment. Analysed of IL-6 and NAS score+fibrotic with Kruskal Wallis to Mann Whitney and analysed of SOD with One-Way ANOVA to LSD. Results: The study showed that there were significant differences in IL-6, SOD and NAS score + fibrotic between groups. Discussion: Provision of 0,054 gr and 0,108 gr have hepatoprotective potential toward hepar injury rats induced by carbon tetrachlorida. Further research need to identify antioxidants and hepatoprotective potential of propolis on human with liver disease. Keywords: IL-6, SOD, fibrotic, propolis

MIPAS IMK/IAA carbon tetrachloride (CCl4) retrieval and first comparison with other instruments

Science.gov (United States)

Eckert, Ellen; von Clarmann, Thomas; Laeng, Alexandra; Stiller, Gabriele P.; Funke, Bernd; Glatthor, Norbert; Grabowski, Udo; Kellmann, Sylvia; Kiefer, Michael; Linden, Andrea; Babenhauserheide, Arne; Wetzel, Gerald; Boone, Christopher; Engel, Andreas; Harrison, Jeremy J.; Sheese, Patrick E.; Walker, Kaley A.; Bernath, Peter F.

2017-07-01

MIPAS thermal limb emission measurements were used to derive vertically resolved profiles of carbon tetrachloride (CCl4). Level-1b data versions MIPAS/5.02 to MIPAS/5.06 were converted into volume mixing ratio profiles using the level-2 processor developed at Karlsruhe Institute of Technology (KIT) Institute of Meteorology and Climate Research (IMK) and Consejo Superior de Investigaciones Científicas (CSIC), Instituto de Astrofísica de Andalucía (IAA). Consideration of peroxyacetyl nitrate (PAN) as an interfering species, which is jointly retrieved, and CO2 line mixing is crucial for reliable retrievals. Parts of the CO2 Q-branch region that overlap with the CCl4 signature were omitted, since large residuals were still found even though line mixing was considered in the forward model. However, the omitted spectral region could be narrowed noticeably when line mixing was accounted for. A new CCl4 spectroscopic data set leads to slightly smaller CCl4 volume mixing ratios. In general, latitude-altitude cross sections show the expected CCl4 features with highest values of around 90 pptv at altitudes at and below the tropical tropopause and values decreasing with altitude and latitude due to stratospheric decomposition. Other patterns, such as subsidence in the polar vortex during winter and early spring, are also visible in the distributions. The decline in CCl4 abundance during the MIPAS Envisat measurement period (July 2002 to April 2012) is clearly reflected in the altitude-latitude cross section of trends estimated from the entire retrieved data set.

MIPAS IMK/IAA carbon tetrachloride (CCl4 retrieval and first comparison with other instruments

Directory of Open Access Journals (Sweden)

E. Eckert

2017-07-01

Full Text Available MIPAS thermal limb emission measurements were used to derive vertically resolved profiles of carbon tetrachloride (CCl4. Level-1b data versions MIPAS/5.02 to MIPAS/5.06 were converted into volume mixing ratio profiles using the level-2 processor developed at Karlsruhe Institute of Technology (KIT Institute of Meteorology and Climate Research (IMK and Consejo Superior de Investigaciones Científicas (CSIC, Instituto de Astrofísica de Andalucía (IAA. Consideration of peroxyacetyl nitrate (PAN as an interfering species, which is jointly retrieved, and CO2 line mixing is crucial for reliable retrievals. Parts of the CO2 Q-branch region that overlap with the CCl4 signature were omitted, since large residuals were still found even though line mixing was considered in the forward model. However, the omitted spectral region could be narrowed noticeably when line mixing was accounted for. A new CCl4 spectroscopic data set leads to slightly smaller CCl4 volume mixing ratios. In general, latitude–altitude cross sections show the expected CCl4 features with highest values of around 90 pptv at altitudes at and below the tropical tropopause and values decreasing with altitude and latitude due to stratospheric decomposition. Other patterns, such as subsidence in the polar vortex during winter and early spring, are also visible in the distributions. The decline in CCl4 abundance during the MIPAS Envisat measurement period (July 2002 to April 2012 is clearly reflected in the altitude–latitude cross section of trends estimated from the entire retrieved data set.

Hepatoprotective Effect of Cuscuta campestris Yunck. Whole Plant on Carbon Tetrachloride Induced Chronic Liver Injury in Mice.

Science.gov (United States)

Peng, Wen-Huang; Chen, Yi-Wen; Lee, Meng-Shiou; Chang, Wen-Te; Tsai, Jen-Chieh; Lin, Ying-Chih; Lin, Ming-Kuem

2016-12-07

Cuscuta seeds and whole plant have been used to nourish the liver and kidney. This study was aimed to investigate the hepatoprotective activity of the ethanol extract of Cuscuta campestris Yunck. whole plant (CC EtOH ). The hepatoprotective effect of CC EtOH (20, 100 and 500 mg/kg) was evaluated on carbon tetrachloride (CCl₄)-induced chronic liver injury. Serum alanine aminotransferase, aspartate aminotransferase, triglyceride and cholesterol were measured and the fibrosis was histologically examined. CC EtOH exhibited a significant inhibition of the increase of serum alanine aminotransferase, aspartate aminotransferase, triglyceride and cholesterol. Histological analyses showed that fibrosis of liver induced by CCl₄ were significantly reduced by CC EtOH . In addition, 20, 100 and 500 mg/kg of the extract decreased the level of malondialdehyde (MDA) and enhanced the activities of anti-oxidative enzymes including superoxide dismutase (SOD), glutathione peroxidase (GPx) and glutathione reductase (GRd) in the liver. We demonstrate that the hepatoprotective mechanisms of CC EtOH were likely to be associated to the decrease in MDA level by increasing the activities of antioxidant enzymes such as SOD, GPx and GRd. In addition, our findings provide evidence that C. campestris Yunck. whole plant possesses a hepatoprotective activity to ameliorate chronic liver injury.

Hepatoprotective Effect of Cuscuta campestris Yunck. Whole Plant on Carbon Tetrachloride Induced Chronic Liver Injury in Mice

Directory of Open Access Journals (Sweden)

Wen-Huang Peng

2016-12-01

Full Text Available Cuscuta seeds and whole plant have been used to nourish the liver and kidney. This study was aimed to investigate the hepatoprotective activity of the ethanol extract of Cuscuta campestris Yunck. whole plant (CCEtOH. The hepatoprotective effect of CCEtOH (20, 100 and 500 mg/kg was evaluated on carbon tetrachloride (CCl4-induced chronic liver injury. Serum alanine aminotransferase, aspartate aminotransferase, triglyceride and cholesterol were measured and the fibrosis was histologically examined. CCEtOH exhibited a significant inhibition of the increase of serum alanine aminotransferase, aspartate aminotransferase, triglyceride and cholesterol. Histological analyses showed that fibrosis of liver induced by CCl4 were significantly reduced by CCEtOH. In addition, 20, 100 and 500 mg/kg of the extract decreased the level of malondialdehyde (MDA and enhanced the activities of anti-oxidative enzymes including superoxide dismutase (SOD, glutathione peroxidase (GPx and glutathione reductase (GRd in the liver. We demonstrate that the hepatoprotective mechanisms of CCEtOH were likely to be associated to the decrease in MDA level by increasing the activities of antioxidant enzymes such as SOD, GPx and GRd. In addition, our findings provide evidence that C. campestris Yunck. whole plant possesses a hepatoprotective activity to ameliorate chronic liver injury.

Project Rio Blanco: site restoration. Final report

International Nuclear Information System (INIS)

1978-01-01

Project Rio Blanco was a joint Government-industry experiment using nuclear explosives to stimulate the flow of natural gas from low permeability formations which could not be economically produced through conventional methods. The project consisted of the simultaneous detonation of three nuclear explosives on May 17, 1973, in a 7,000 foot well in northwestern Colorado. Gas production testing and project evaluation continued through June 1976. The site cleanup and restoration planning phase began in December 1975 and was concluded with the issuance of an operational plan, Project Rio Blanco Site Cleanup and Restoration Plan, NVO-173, in May 1976. Actual site restoration activities were conducted during the period from July to November 1976. The activities throughout the restoration period are summarized and the final site status, including the disposition of all project facilities and the status of all project related wells after plug and abandonment and recompletion work are described

The low energy booster project status

International Nuclear Information System (INIS)

Tuttle, G.W.

1993-05-01

In order to achieve the required injection momentum, the Superconducting Super Collider (SSC) has an accelerator chain comprised of a Linear Accelerator and three synchrotrons. The Low Energy Booster (LEB) is the first synchrotron in this chain. The LEB project has made significant progress in the development of major subsystems and conventional construction. This paper briefly reviews the performance requirements of the LEB and describes significant achievements in each of the major subsystem areas. Highlighted among these achievements are the LEB foreign collaborations with the Budker Institute of Nuclear Physics (BINP) located in Novosibirsk, Russia

Progress, status, and plans for the HRIBF project

International Nuclear Information System (INIS)

Auble, R.L.; Alton, G.D.; Bailey, J.D.

1995-01-01

Over the last three years, the Holifield accelerator system has been reconfigured into a first-generation radioactive ion beam facility, the HRIBF, a national user facility for RIB research. The construction and reconfiguration have been completed and the equipment commissioning and beam development phases have started. The progress to date, the present status, and future plans will be given. The special problems connected with the production and acceleration of RIBs will be discussed

Status of the Forward Physics Projects in ATLAS

OpenAIRE

Ask, Stefan

2007-01-01

The ATLAS experiment at the LHC is building several detector systems for forward physics studies and to determine the luminosity. The main forward systems consist of a Cerenkov detector called LUCID, a Zero Degree Calorimeter (ZDC) and Roman Pots which will house a scintillating fiber tracker system called ALFA. Here we report some of the forward physics activities that are foreseen in ATLAS together with the status of the related detector systems.

Comparative study on the inhibitory effects of antioxidant vitamins and radon on carbon tetrachloride-induced hepatopathy

International Nuclear Information System (INIS)

Kataoka, Takahiro; Nishiyama, Yuichi; Yamato, Keiko; Teraoka, Junichi; Morii, Yuji; Taguchi, Takehito; Yamaoka, Kiyonori; Sakoda, Akihiro; Ishimori, Yuu

2012-01-01

We have previously reported that radon inhalation activates anti-oxidative functions and inhibits carbon tetrachloride (CCl 4 )-induced hepatopathy. It has also been reported that antioxidant vitamins can inhibit CCl 4 -induced hepatopathy. In the current study, we examined the comparative efficacy of treatment with radon, ascorbic acid and α-tocopherol on CCl 4 -induced hepatopathy. Mice were subjected to intraperitoneal injection of CCl 4 after inhaling approximately 1000 or 2000 Bq/m 3 radon for 24 h, or immediately after intraperitoneal injection of ascorbic acid (100, 300, or 500 mg/kg bodyweight) or α-tocopherol (100, 300, or 500 mg/kg bodyweight). We estimated the inhibitory effects on CCl 4 -induced hepatopathy based on hepatic function-associated parameters, oxidative damage-associated parameters and histological changes. The results revealed that the therapeutic effects of radon inhalation were almost equivalent to treatment with ascorbic acid at a dose of 500 mg/kg or α-tocopherol at a dose of 300 mg/kg. The activities of superoxide dismutase, catalase, and glutathione peroxidase in the liver were significantly higher in mice exposed to radon than in mice treated with CCl 4 alone. These findings suggest that radon inhalation has an anti-oxidative effect against CCl 4 -induced hepatopathy similar to the anti-oxidative effects of ascorbic acid or α-tocopherol due to the induction of anti-oxidative functions. (author)

Western Gas Sands Project. Status report, 1 August-31 August, 1979

Energy Technology Data Exchange (ETDEWEB)

None

1979-01-01

This status report summarizes progress of government-sponsored projects directed toward increasing gas production from the low-permeability gas sands of the western United States. Work on fracture conductivity, rock-fluid interaction, and log evaluation and interpretation techniques continued at Bartlesville. Work commenced on completing, testing and possible hydraulic fracturing of the Rio Blanco Natural Gas Company well No. 397-19-1 and on the evaluation of seismic data for stratigraphic studies of lenticular sands. LLL continued experimental and theoretical work on hydraulic fracturing mechanics and analysis of well test data. LASL worked on developing NMR methods to define fluid saturation, porosity, and permeability of western gas sands at in situ conditions. M.D. Wood, Inc. was involved in design and site preparation for two hydraulic fracture mapping jobs in the Cotton Valley Trend in Texas. Testing and analyses of the borehole seismic system and borehole hydrophone system continued at Sandia. Field tests and related activities for the WGSP progressed as scheduled in August. Cyclic injection of dehydrated natural gas and production in Colorado Interstate Gas Company's Miller No. 1 and Sprague No. 1 wells continued. The Gas Producing Enterprises, Inc. wells, Natural Buttes Units 9, 14, 18 and 20 flowed to sales. The Mitchell Energy Corporation Muse-Duke No. 1 was shut-in for a 15-day pressure buildup test. Hydraulic fracture containment experiments and activities in the multi-frac test series continued at the Nevada Test Site for Sandia Laboratories' mineback program.

Status of the project of Novosibirsk high power FEL

Energy Technology Data Exchange (ETDEWEB)

Pinayev, I.V.; Erg, G.I.; Gavrilov, N.G. [Budker Institute of Nuclear Physics, Novosibirsk (Russian Federation)] [and others

1995-12-31

The project of IR FEL for the Siberian Center of photochemical researches is described. The distinguished features of this project are the use of the race-track microtron-recuperator and the {open_quotes}electron output of radiation{close_quotes}. The building for the machine is under reconstruction now. About half of hardware has been manufactured. The assembly of installation began.

The EFF Project Status and the NEA Nuclear Data Services

International Nuclear Information System (INIS)

Henriksson, H.; Kodeli, I.; Nordborg, C.; Forrest, R.; Batistoni, P.; Fischer, U.

2006-01-01

The OECD Nuclear Energy Agency (NEA) Data Bank is part of an international network of data centres in charge of the compilation and dissemination of basic nuclear data. Through its activities in the reaction data field, the NEA participates in the production of data and their distribution to its users. The NEA Data Bank administrates the collection and validation as well as the distribution of the Joint Evaluated Fusion and Fission (JEFF) library. The JEFF project has evolved from two separate projects, namely the European Fusion File (EFF) and the Joint Evaluated File (JEF), to JEFF with the latest release of the library, JEFF-3.1, in May 2005. The EFF Project is a collaborative project with work funded by the European Fusion Development Agreement (EFDA). The tasks within the project comprise new data evaluation and verification of activation and transport data, calculation methods and validation via integral experiments. The EFF project brings together all available expertise in Europe, relating to the nuclear data requirements of existing and future fusion devices. EFF contributed greatly to the successful release of the internationally recognised nuclear data library JEFF-3.1. The NEA Working Party on International Nuclear Data Evaluation Co-operation (WPEC) is established to promote the exchange of information on nuclear data evaluations, measurements, nuclear model calculations and validation. WPEC provides a framework for co-operative activities between the participating projects, such as the high priority request list that is a collection of experimental data requests of special interest in a certain project, such as JEFF or ITER. The NEA provides also computer program services for nuclear energy and radiation physics applications. Of special interest for fusion applications are the integral experiments, such as SINBAD, with radiation shielding and dosimetry experiments including many fusion neutronics shielding experiments. (author)

Solvent extraction of europium(III) with benzoylacetone and benzoyltrifluoroacetone into carbon tetrachloride in the absence and presence of tetrabutylammonium ions

International Nuclear Information System (INIS)

Noro, Junji; Sekine, Tatsuya.

1992-01-01

The solvent extraction of europium (III) in 0.1 mol dm -3 sodium nitrate solutions with benzoylacetone (Hbza) or benzoyltrifluoroacetone (Hbfa) in carbon tetrachloride was measured in the absence and presence or tetrabutylammonium ions (tba + ). Although extraction with Hbfa occurred at lower pH than with Hbza, the extraction measured as a function of the β-diketonate ion concentration in the aqueous phase was rather similar. It was also found that extraction with Hbfa was greatly enhanced by the addition of tba + , the effect, however, was negligible with Hbza. The data were analyzed from the stand point that the neutral metal chelate, Eu(bfa) 3 , was extracted into the organic phase and associated with ion-pairs of the reagents, bfa - tba + , in this phase. It was also found that though extraction of ion-pairs of bfa - tba + occurred, that of bza - tba + was negligible. Thus, the reason for the negligible extraction of the ternary complex, Eu (bza) 4 - tba + , was explained in terms of the negligible extraction of the bza - tba + , which might associate with Eu(bza) 3 in the organic phase. (author)

J-PARC project

International Nuclear Information System (INIS)

Nagamiya, Shoji

2004-01-01

From Japanese fiscal year JFY01, which started on April 1, 2001, a new accelerator project to provide high-intensity proton beams proceeded into its construction phase. This project, which is now called the Japan Proton Accelerator Research Complex (J-PARC) project, is conducted under a cooperation of two institutions, KEK and Japan Atomic Energy Research Institution. We set a goal to achieve 1 MW proton beams at 3 GeV and 0.75 MW beams at 50 GeV. The project will be completed within six years, with the anticipated first beams in the spring of 2007. In this article I will describe (a) the project itself, (b) sciences to be pursued at this new accelerator complex and (c) the present status and future plans of the project

Medical Data Architecture (MDA) Project Status

Science.gov (United States)

Krihak, M.; Middour, C.; Gurram, M.; Wolfe, S.; Marker, N.; Winther, S.; Ronzano, K.; Bolles, D.; Toscano, W.; Shaw, T.

2018-01-01

The Medical Data Architecture (MDA) project supports the Exploration Medical Capability (ExMC) risk to minimize or reduce the risk of adverse health outcomes and decrements in performance due to in-flight medical capabilities on human exploration missions. To mitigate this risk, the ExMC MDA project addresses the technical limitations identified in ExMC Gap Med 07: We do not have the capability to comprehensively process medically-relevant information to support medical operations during exploration missions. This gap identifies that the current in-flight medical data management includes a combination of data collection and distribution methods that are minimally integrated with on-board medical devices and systems. Furthermore, there are a variety of data sources and methods of data collection. For an exploration mission, the seamless management of such data will enable a more medically autonomous crew than the current paradigm. The medical system requirements are being developed in parallel with the exploration mission architecture and vehicle design. ExMC has recognized that in order to make informed decisions about a medical data architecture framework, current methods for medical data management must not only be understood, but an architecture must also be identified that provides the crew with actionable insight to medical conditions. This medical data architecture will provide the necessary functionality to address the challenges of executing a self-contained medical system that approaches crew health care delivery without assistance from ground support. Hence, the products supported by current prototype development will directly inform exploration medical system requirements.

Krsko 2 Project Preparation and Status

International Nuclear Information System (INIS)

Novsak, M.; Spiler, J.; Bergant, R.; Zagar, T.

2008-01-01

The Government of the Republic of Slovenia has adopted a document 'Resolution on National Development Projects for the period 2007 - 2023' in October 2006. Among several projects which all support sustainable development of Slovenia, an option of a new nuclear power plant was proposed. Thus, the Slovenian Government showed obvious intention and direction of Slovenian future energetic situation. The supply of electricity has been sharpening in Slovenia in the last few years. Growing of gross domestic product (GDP) and approaching to the life standard of developed EU countries has caused increased consumption of electricity. Since domestic electricity production does not follow the increased consumption, Slovenia already imports nearly a quarter of its needed electricity. Slovenia would need 400 MW of installed electrical power now for covering of its base load needs only. Based on recent electricity consumption forecasts, Slovenia will need 800 MW of new electricity generation capacities by 2015 and 1500 MW by 2025 respectively. Besides high annual growth rate and high dependence on electricity import, a problem of relatively old power generation objects and realization of new energy and climate package for Europe exists. All together dictates our options for expansion of capacity production of the proposed Nuclear power plant Krsko 2. Experience and knowledge of light water pressurized reactor can be effectively used at NPP Krsko 2. Planned NPP Krsko 2 would have between 1100 and 1600 MW of installed electrical power. If the decision is taken in 2009, construction could start in 2013 and finish in 2017. (author)

The SMILING project

DEFF Research Database (Denmark)

Berger, Jacques; Blanchard, Gentiane; Ponce, Maiza Campos

2013-01-01

The "Sustainable Micronutrient Interventions to Control Deficiencies and Improve Nutritional Status and General Health in Asia" project (SMILING), funded by the European Commission, is a transnational collaboration of research institutions and implementation agencies in five Southeast Asian count...

Business Intelligence Support For Project Management

OpenAIRE

Muntean, Mihaela; Cabau, Liviu Gabiel

2013-01-01

With respect to the project management framework, a project live cycle consists of phases like: initiation, planning, execution, monitoring & control and closing. Monitoring implies measuring the progress and performance of the project during its execution and communicating the status. Actual performance is compared with the planned one. Therefore, a minimal set of key performance indicators will be proposed. Monitoring the schedule progress, the project budget and the scope will be possible....

Model sensitivity studies of the decrease in atmospheric carbon tetrachloride

Directory of Open Access Journals (Sweden)

M. P. Chipperfield

2016-12-01

Full Text Available Carbon tetrachloride (CCl4 is an ozone-depleting substance, which is controlled by the Montreal Protocol and for which the atmospheric abundance is decreasing. However, the current observed rate of this decrease is known to be slower than expected based on reported CCl4 emissions and its estimated overall atmospheric lifetime. Here we use a three-dimensional (3-D chemical transport model to investigate the impact on its predicted decay of uncertainties in the rates at which CCl4 is removed from the atmosphere by photolysis, by ocean uptake and by degradation in soils. The largest sink is atmospheric photolysis (74 % of total, but a reported 10 % uncertainty in its combined photolysis cross section and quantum yield has only a modest impact on the modelled rate of CCl4 decay. This is partly due to the limiting effect of the rate of transport of CCl4 from the main tropospheric reservoir to the stratosphere, where photolytic loss occurs. The model suggests large interannual variability in the magnitude of this stratospheric photolysis sink caused by variations in transport. The impact of uncertainty in the minor soil sink (9 % of total is also relatively small. In contrast, the model shows that uncertainty in ocean loss (17 % of total has the largest impact on modelled CCl4 decay due to its sizeable contribution to CCl4 loss and large lifetime uncertainty range (147 to 241 years. With an assumed CCl4 emission rate of 39 Gg year−1, the reference simulation with the best estimate of loss processes still underestimates the observed CCl4 (overestimates the decay over the past 2 decades but to a smaller extent than previous studies. Changes to the rate of CCl4 loss processes, in line with known uncertainties, could bring the model into agreement with in situ surface and remote-sensing measurements, as could an increase in emissions to around 47 Gg year−1. Further progress in constraining the CCl4 budget is partly limited by

Status seminar `98: Solar-supported district heating with seasonal heat storage. Status report `98; Status-Seminar `98: Solarunterstuetzte Nahwaermeversorgung - Saisonale Waermespeicherung. Statusbericht `98

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-12-31

This status report refers to the BMBF (Federal Ministry for Education, Science, Research and Technology) status seminar: Solar-assisted district heat supply - seasonal heat storage that took place in Neckarsulm on 19th and 20th May. 1998. The report contains the reference papers and the status reports of all projects supported under the Ministry`s SOLARTHERMIE programme that have already been finished or are still running. (orig.) [Deutsch] Der vorliegende Statusbericht wird anlaesslich des BMBF-Statusseminars: Solarunterstuetzte Nahwaermeversorgung - Saisonale Waermespeicherung am 19. und 20. Mai 1998 in Neckarsulm herausgegeben. Der Bericht enthaelt neben den Tagungsbeitraegen auch die Sachstandsberichte aller Projekte, die zu diesem Thema in den letzten Jahren von BMBF in dem Programm SOLARTHERMIE-2000 bereits abgeschlossen wurden oder z.Zt. gefoerdert werden. (orig.)

Status of the ATLAS Positive-Ion Injector Project

International Nuclear Information System (INIS)

Pardo, R.C.; Benaroya, R.; Billquist, P.J.

1987-01-01

The goal of the Argonne Positive Ion Injector project is to replace the ATLAS tandem injector with a facility which will increase the beam currents presently available by a factor of 100 and to make available at ATLAS essentially all beams including uranium. The beam quality expected from the facility will be at least as good as that of the tandem based ATLAS. The project combines two relatively new technologies - the electron cyclotron resonance ion source, which provides high charge state ions at microampere currents, and RF superconductivity which has been shown to be capable of generating accelerating fields as high as 10 MV/m, resulting in an essentially new method of acceleration for low-energy heavy ions. 5 refs., 7 figs., 1 tabs

FRIB Cryogenic Plant Status

Energy Technology Data Exchange (ETDEWEB)

Dixon, Kelly D. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Ganni, Venkatarao [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Knudsen, Peter N. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Casagranda, Fabio [Michigan State Univ., East Lansing, MI (United States)

2015-12-01

After practical changes were approved to the initial conceptual design of the cryogenic system for MSU FRIB and an agreement was made with JLab in 2012 to lead the design effort of the cryogenic plant, many activities are in place leading toward a cool-down of the linacs prior to 2018. This is mostly due to using similar equipment used at CHLII for the 12 GeV upgrade at JLab and an aggressive schedule maintained by the MSU Conventional Facilities department. Reported here is an updated status of the cryogenic plant, including the equipment procurement status, plant layout, facility equipment and project schedule.

The MAJORANA Project: a status report

Energy Technology Data Exchange (ETDEWEB)

Elliott, Steven Ray [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2015-06-09

This series of slides presents the topic under the following aspects: ββ sensitivity, underground laboratory, shield, monoliths, strings, detectors, electroformed small parts, and background. Assembly and construction are proceeding at Sanford Davis Campus laboratory. Based on assays, material backgrounds are projected to meet cleanliness goals. Module 1 is complete. Electroformed copper has just been completed at SURF and PNNL. The shield is nearly complete. Successful reduction and refinement of ^enrGe has taken place with 98% yield. AMTEK (ORTEC) has produced 27 kg within 32 detectors from the reduced/refined ^enrGe; 30 of these are underground at SURF being assembled into strings.

Status of the NICA project at JINR

Directory of Open Access Journals (Sweden)

Kekelidze Vladimir

2017-01-01

Full Text Available The NICA (Nuclotron-based Ion Collider fAcility project is now under active realization at the Joint Institute for Nuclear Research (JINR, Dubna. The main goal of the project is a study of hot and dense strongly interacting matter in heavy-ion (up to Au collisions at the center-of-mass energies up to 11 GeV per nucleon. Two modes of operation are foreseen, collider mode and extracted beams, with two detectors: MPD and BM@N. The both experiments are in preparation stage. An average luminosity in the collider mode is expected to be 1027 cm−2 s−1 for Au (79+. Extracted beams of various nuclei with maximum momenta of 13 GeV/c (for protons will be available. A study of spin physics with extracted and colliding beams of polarized deuterons and protons at energies up to 27 GeV (for protons is foreseen with the NICA facility. The proposed program allows one to search for possible signs of phase transitions and critical phenomena as well as to shed light on the problem of the nucleon spin structure.

Salt Repository Project: FY 85 technical project plan

International Nuclear Information System (INIS)

1985-07-01

The FY 85 technical plan for the Salt Repository Project is briefly presented. The objectives of the project in relation to the Civilian Radioactive Waste Management Program are discussed, and the technical activities directed toward accomplishing these objectives are detailed. A budget is presented for each of the Level 2 work breakdown structure tasks (Systems, Waste Package, Site, Repository, Regulatory and Institutional, Exploratory Shaft, Test Facilities, Land Acquisition, and Project Management) in the various sections. An overall description, current status, and planned activities are presented for each of the subtasks which make up the above-mentioned Level 2 tasks. A strategy diagram and a master schedule are included and each of the milestones is also listed chronologically in the sections

Effect of WeiJia on carbon tetrachloride induced chronic liver injury

Science.gov (United States)

Cheung, Pik-Yuen; Zhang, Qi; Zhang, Ya-Ou; Bai, Gan-Rong; Lin, Marie Chia-Mi; Chan, Bernard; Fong, Chi-Chun; Shi, Lin; Shi, Yue-Feng; Chun, Jay; Kung, Hsiang-Fu; Yang, Mengsu

2006-01-01

AIM: To study the effect of WeiJia on chronic liver injury using carbon tetrachloride (CCl4) induced liver injury animal model. METHODS: Wistar rats weighing 180-220g were randomly divided into three groups: normal control group (Group A), CCl4 induced liver injury control group (Group B) and CCl4 induction with WeiJia treatment group (Group C). Each group consisted of 14 rats. Liver damage and fibrosis was induced by subcutaneous injection with 40% CCl4 in olive oil at 3 mL/kg body weight twice a week for eight weeks for Groups B and C rats whereas olive oil was used for Group A rats. Starting from the third week, Group C rats also received daily intraperitoneal injection of WeiJia at a dose of 1.25 μg/kg body weight. Animals were sacrificed at the fifth week (4 male, 3 female), and eighth week (4 male, 3 female) respectively. Degree of fibrosis were measured and serological markers for liver fibrosis and function including hyaluronic acid (HA), type IV collagen (CIV), γ-glutamyl transferase (γ-GT), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were determined. Alpha smooth muscle actin (α-SMA) and proliferating cell nuclear antigen (PCNA) immunohistochemistry were also performed. RESULTS: CCl4 induction led to the damage of liver and development of fibrosis in Group B and Group C rats when compared to Group A rats. The treatment of WeiJia in Group C rats could reduce the fibrosis condition significantly compared to Group B rats. The effect could be observed after three weeks of treatment and was more obvious after eight weeks of treatment. Serum HA, CIV, ALT, AST and γ-GT levels after eight weeks of treatment for Group C rats were 58±22 µg/L (P0.05) respectively, similar to normal control group (Group A), but significantly different from CCl4 induced liver injury control group (Group B). An increase in PCNA and decrease in α-SMA expression level was also observed. CONCLUSION: WeiJia could improve liver function and reduce liver

Phenylbutyric acid protects against carbon tetrachloride-induced hepatic fibrogenesis in mice

Energy Technology Data Exchange (ETDEWEB)

Wang, Jian-Qing [School of Pharmacy, Anhui Medical University, Hefei, 230032 (China); Second Affiliated Hospital, Anhui Medical University, Hefei 230601 (China); Chen, Xi [First Affiliated Hospital, Anhui Medical University, Hefei 230022 (China); Zhang, Cheng [Department of Toxicology, Anhui Medical University, Hefei, 230032 (China); Tao, Li [First Affiliated Hospital, Anhui Medical University, Hefei 230022 (China); Zhang, Zhi-Hui; Liu, Xiao-Qian [Department of Toxicology, Anhui Medical University, Hefei, 230032 (China); Xu, Yuan-Bao [Department of Toxicology, Anhui Medical University, Hefei, 230032 (China); First Affiliated Hospital, Anhui Medical University, Hefei 230022 (China); Wang, Hua [Department of Toxicology, Anhui Medical University, Hefei, 230032 (China); Li, Jun, E-mail: lijun@ahmu.edu.cn [School of Pharmacy, Anhui Medical University, Hefei, 230032 (China); Xu, De-Xiang, E-mail: xudex@126.com [Department of Toxicology, Anhui Medical University, Hefei, 230032 (China)

2013-01-15

A recent report showed that the unfolded protein response (UPR) signaling was activated in the pathogenesis of carbon tetrachloride (CCl{sub 4})-induced hepatic fibrosis. Phenylbutyric acid (PBA) is a well-known chemical chaperone that inhibits endoplasmic reticulum (ER) stress and unfolded protein response (UPR) signaling. In the present study, we investigated the effects of PBA on CCl{sub 4}-induced hepatic fibrosis in mice. All mice were intraperitoneally (i.p.) injected with CCl{sub 4} (0.15 ml/kg BW, twice per week) for 8 weeks. In CCl{sub 4} + PBA group, mice were i.p. injected with PBA (150 mg/kg, twice per day) from the beginning of CCl{sub 4} injection to the end. As expected, PBA significantly attenuated CCl{sub 4}-induced hepatic ER stress and UPR activation. Although PBA alleviated, only to a less extent, hepatic necrosis, it obviously inhibited CCl{sub 4}-induced tumor necrosis factor alpha (TNF-α) and transforming growth factor beta (TGF-β). Moreover, PBA inhibited CCl{sub 4}-induced hepatic nuclear factor kappa B (NF-κB) p65 translocation and extracellular signal-regulated kinase (ERK) and c-Jun N-terminal Kinase (JNK) phosphorylation. Interestingly, CCl{sub 4}-induced α-smooth muscle actin (α-SMA), a marker for the initiation phase of HSC activation, was significantly attenuated in mice pretreated with PBA. Correspondingly, CCl{sub 4}-induced hepatic collagen (Col)1α1 and Col1α2, markers for the perpetuation phase of HSC activation, were inhibited in PBA-treated mice. Importantly, CCl{sub 4}-induced hepatic fibrosis, as determined using Sirius red staining, was obviously attenuated by PBA. In conclusion, PBA prevents CCl{sub 4}-induced hepatic fibrosis through inhibiting hepatic inflammatory response and HSC activation. Highlights: ► CCl{sub 4} induces hepatic ER stress, inflammation, HSC activation and hepatic fibrosis. ► PBA alleviates CCl{sub 4}-induced hepatic ER stress and UPR signaling activation. ► PBA inhibits CCl{sub 4}-induced

Hepatoprotective effect of Scoparia dulcis on carbon tetrachloride induced acute liver injury in mice.

Science.gov (United States)

Tsai, Jen-Chieh; Peng, Wen-Huang; Chiu, Tai-Hui; Huang, Shun-Chieh; Huang, Tai-Hung; Lai, Shang-Chih; Lai, Zhen-Rung; Lee, Chao-Ying

2010-01-01

This study aims to investigate the hepatoprotective activity and active constituents of the ethanol extract of Scoparia dulcis (SDE). The hepatoprotective effect of SDE (0.1, 0.5 and 1 g/kg) was evaluated on the carbon tetrachloride (CCl(4))-induced acute liver injury. The active constituents were detected by high performance liquid chromatography (HPLC). Mice pretreated orally with SDE (0.5 and 1.0 g/kg) and silymarin (200 mg/kg) for five consecutive days before the administering of a single dose of 0.2% CCl(4) (10 ml/kg of bw, ip) showed a significant inhibition of the increase of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Histological analyses also showed that SDE (0.5 and 1.0 g/kg) and silymarin reduced the extent of liver lesions induced by CCl(4), including vacuole formation, neutrophil infiltration and necrosis. Moreover, SDE decreased the malondialdehyde (MDA) level and elevated the content of reduced glutathione (GSH) in the liver as compared to those in the CCl(4) group. Furthermore, SDE (0.5 and 1.0 g/kg) enhanced the activities of anti-oxidative enzymes including superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione reductase (GRd) and glutathione-S-transferase (GST). The quantities of active constituents in SDE were about 3.1 mg luteolin/g extract and 1.1 mg apigenin/g extract. The hepatoprotective mechanisms of SDE were likely associated to the decrease in MDA level and increase in GSH level by increasing the activities of antioxidant enzymes such as SOD, GPx, GRd and GST. These results demonstrated that SDE could alleviate CCl(4)-induced acute liver injury in mice.

The Carolina Bay Restoration Project - Status Report II 2000-2004.

Energy Technology Data Exchange (ETDEWEB)

Barton, Christopher

2006-07-13

A Wetlands Mitigation Bank was established at SRS in 1997 as a compensatory alternative for unavoidable wetland losses. Prior to restoration activities, 16 sites included in the project were surveyed for the SRS Site Use system to serve as a protective covenant. Pre-restoration monitoring ended in Fall 2000, and post restoration monitoring began in the Winter/Spring of 2001. The total interior harvest in the 16 bays after harvesting the trees was 19.6 ha. The margins in the opencanopy, pine savanna margin treatments were thinned. Margins containing areas with immature forested stands (bay 5184 and portions of bay 5011) were thinned using a mechanical shredder in November 2001. Over 126 hectares were included in the study areas (interior + margin). Planting of two tree species and the transplanting of wetland grass species was successful. From field surveys, it was estimated that approximately 2700 Nyssa sylvatica and 1900 Taxodium distichum seedlings were planted in the eight forested bays resulting in an average planting density of ≈ 490 stems ha-1. One hundred seedlings of each species per bay (where available) were marked to evaluate survivability and growth. Wetland grass species were transplanted from donor sites on SRS to plots that ranged in size from 100 – 300 m2, depending on wetland size. On 0.75 and 0.6 meter centers, respectively, 2198 plugs of Panicum hemitomon and 3021 plugs Leersia hexandra were transplanted. New shoots originating from the stumps were treated with a foliar herbicide (Garlon® 4) during the summer of 2001 using backpack sprayers. Preliminary information from 2000-2004 regarding the hydrologic, vegetation and faunal response to restoration is presented in this status report. Post restoration monitoring will continue through 2005. A final report to the Mitigation Bank Review Team will be submitted in mid-2006.

Update on the status of the West Valley demonstration project

International Nuclear Information System (INIS)

Greeves, J.T.; Camper, L.W.; Orlando, D.A.; Glenn, C.J.; Buckley, J.T.; Giardina, P.A.

2002-01-01

From 1966 to 1972, under an Atomic Energy Commission (AEC) license, Nuclear Fuel Services (NFS) reprocessed 640 metric tons of spent fuel at its West Valley, New York, facility-, the only commercial spent fuel reprocessing plant in the U.S. The facility shut down in 1972, for modifications to increase its seismic stability and to expand its capacity. In 1976, without restarting the operation, NFS withdrew from the reprocessing business and returned control of the facilities to the site owner, the New York State Energy Research and Development Authority (NYSERDA). The reprocessing activities resulted in about 2.3 million liters (600,000 gallons) of liquid high-level waste (HLW) stored below ground in tanks, other radioactive wastes, and residual radioactive contamination. The West Valley site was licensed by AEC, and then the U.S. Nuclear Regulatory Commission (NRC), until 1981, when the license was suspended to execute the 1980 West Valley Demonstration Project (WVDP) Act. The WVDP Act outlines the responsibilities of the U.S. Department of Energy (DOE), NRC, and NYSERDA at the site, including the NRC's responsibility to develop decommissioning criteria for the site. The Commission published the final policy statement on decommissioning criteria for the WVDP at the West Valley site after considering comments from interested stakeholders. In that regard, the Commission prescribed the License Termination Rule (LTR) criteria for the WVDP at the West Valley site, reflecting the fact that the applicable decommissioning goal for the entire NRC-licensed site is compliance with the requirements of the LTR. This paper will describe the history of the site, provide an update of the status of the decommissioning of the site and an overview of the technical and policy issues facing Federal and State regulators and other stakeholders as they strive to complete the remediation of the site. (author)

Vitamin D Pooling Project

Science.gov (United States)

The Vitamin D Pooling Project of Rarer Cancers brought together investigators from 10 cohorts to conduct a large prospective epidemiologic study of the association between vitamin D status and seven rarer cancers.

Application of MARSSIM for Final Status Survey of the Decommissioning Project

International Nuclear Information System (INIS)

Hong, Sang Bum; Lee, Ki Won; Park, Jin Ho; Chung, Un Soo

2011-01-01

The release of a site and building from regulatory control is the final stage of the decommissioning process. The MARSSIM (Multi-Agency Radiation Survey and Site Investigation Manual) provides overall framework for conducting data collection for a final status survey to demonstrate compliance with site closure requirements. The KAERI carried out establishing a final status survey by using the guidance provided in the MARSSIM for of a site and building of the Korea Research Reactor. The release criteria for a site and building were set up based on these results of the site specific release levels which were calculated by using RESRAD and RESRAD-Build codes. The survey design for a site and building was classified by using the survey dataset and potential contamination. The number of samples in each survey unit was calculated by through a statistical test using the collected data from a scoping and characterization survey. The results of the final status survey were satisfied the release criteria based on an evaluation of the measured data.

Status of the SPARC Project

CERN Document Server

Serafini, Luca; Alessandria, Franco; Bacci, Alberto; Bellaveglia, Marco; Bertolucci, Sergio; Biagini, Maria; Boni, Roberto; Boscolo, Ilario; Boscolo, Manuela; Broggi, Francesco; Castellano, Michele; Catani, Luciano; Chiadroni, Enrica; Cialdi, Simone; Cianchi, Alessandro; Ciocci, Franco; Clozza, Alberto; Dattoli, Giuseppe; De Martinis, Carlo; Di Pirro, Giampiero; Dipace, Antonio; Doria, Andrea; Dowell, David; Drago, Alessandro; Emma, Paul; Esposito, Adolfo; Ferrario, Massimo; Ficcadenti, L; Filippetto, Daniele; Flora, F; Fusco, Valeria; Gabrielli, E; Gallerano, Gian P; Gallo, Alessandro; Gatti, Giancarlo; Ghigo, Andrea; Giannessi, Luca; Giove, Dario; Giovenale, Emilio; Guiducci, Susanna; Incurvati, Maurizio; Levi, Decio; Ligi, Carlo; Limborg-Deprey, Cecile; Marcellini, Fabio; Maroli, Cesare; Mattioli, Mario; Mauri, Marco; Medici, G; Messina, Giovanni; Migliorati, Mauro; Mostacci, Andrea; Musumeci, Pietro; Nisoli, Mauro; Ottaviani, P L; Pagnutti, Simonetta; Palumbo, Luigi; Parisi, Giovanni; Pellegrino, Luigi; Pelliccia, Daniele; Petrarca, Massimo; Petrillo, Vittoria; Picardi, Luigi; Preger, Miro; Quattromini, Marcello; Renieri, Alberto; Ricci, Ruggero; Rome, Massimiliano; Ronci, G; Ronsivalle, Concetta; Rosenzweig, James E; Rosetti, Maurizio; Sabia, Elio; Sanelli, Claudio; Sassi, Mauro; Serio, Mario; Sgamma, Francesco; Spataro, Bruno; Stagira, Salvatore; Stecchi, Alessandro; Stella, Angelo; Tazzari, Sergio; Tazzioli, Franco; Thomas Palmer, Dennis; Torre, A; Vaccarezza, Cristina; Vescovi, Mario; Vicario, Carlo; Zucchini, Alberto; de Silvestri, Sandro

2005-01-01

The SPARC project has entered its installation phase at INFN-LNF: its main goal is the promotion of an R&D activity oriented to the development of a high brightness photoinjector to drive SASE-FEL experiments. The design of the 150 MeV photoinjector has been completed and the construction of its main components is in progress, as well as the design of the 12 m undulator. In this paper we will report on the installation and test of some major components, like the Ti:Sa laser system to drive the photo-cathode, the RF gun, the RF power system, as well as some test results on the RF deflector and 4th harmonic X-band cavity prototypes. Advancements in the control and beam diagnostics systems will also be reported, in particular on the emittance-meter device for beam emittance measurements in the drift space downstream the RF gun. Recent results on laser pulse shaping, obtained with two alternative techniques (DAZZLER and Liquid Crystal Mask), show the feasibility of producing 10 ps flat-top laser pulses in the...

Prevention of carbon tetrachloride (CCl4)-induced toxicity in testes of rats treated with Physalis peruviana L. fruit.

Science.gov (United States)

Abdel Moneim, Ahmed E

2016-06-01

Treatment of rats with carbon tetrachloride (CCl4; 2 ml/kg body weight) once a week for 12 weeks caused a significant decrease in serum levels of testosterone, luteinizing hormone, and follicle-stimulating hormone. These decreases in sex hormones were reduced with Physalis peruviana L. (Cape gooseberry) juice supplementation. In addition, testicular activity of antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, and glutathione-S-transferase suppressed with CCl4 were elevated after P. peruviana juice supplements. P. peruviana juice supplementation significantly increased the testicular glutathione and significantly decreased the level of lipid peroxidation and the nitric oxide production compared with the CCl4 group. In addition, the decline in the activity of antioxidant enzymes after CCl4 was ameliorated by P. peruviana Moreover, degeneration of germ and Leydig cells along with deformities in spermatogenesis induced after CCl4 injections were prevented with the supplementation of P. peruviana juice. Furthermore, P. peruviana juice attenuated CCl4-induced apoptosis in testes tissue by inhibition of caspase-3 activity. The results clearly demonstrate that P. peruviana juice augments the antioxidants defense mechanism against CCl4-induced reproductive toxicity and provides evidence that the juice may have a therapeutic role in free radical-mediated diseases and infertility. © The Author(s) 2014.

Scheduling for decommissioning projects

International Nuclear Information System (INIS)

Podmajersky, O.E.

1987-01-01

This paper describes the Project Scheduling system being employed by the Decommissioning Operations Contractor at the Shippingport Station Decommissioning Project (SSDP). Results from the planning system show that the project continues to achieve its cost and schedule goals. An integrated cost and schedule control system (C/SCS) which uses the concept of earned value for measurement of performance was instituted in accordance with DOE orders. The schedule and cost variances generated by the C/SCS system are used to confirm management's assessment of project status. This paper describes the types of schedules and tools used on the SSDP project to plan and monitor the work, and identifies factors that are unique to a decommissioning project that make scheduling critical to the achievement of the project's goals. 1 fig

49 CFR 268.17 - Project selection criteria.

Science.gov (United States)

2010-10-01

... criteria will govern FRA's selection of projects to receive funding under the Maglev Deployment Program. (a... are to be expected in the United States. (4) The degree to which the project will augment a Maglev... development status of the Maglev technology selected by the applicant for the project. (c) Benefits for the...

How Is the Practice of Yoga Related to Weight Status? Population-Based Findings From Project EAT-IV.

Science.gov (United States)

Neumark-Sztainer, Dianne; MacLehose, Richard F; Watts, Allison W; Eisenberg, Marla E; Laska, Melissa N; Larson, Nicole

2017-12-01

Yoga may provide a strategy for healthy weight management in young adults. This study examined prevalence and characteristics of young adults' yoga practice and associations with changes in body mass index. Surveys were completed by 1830 young adults (31.1 ± 1.6 y) participating in Project EAT-IV. Cross-sectional and 5-year longitudinal analyses were conducted stratified by initial weight status. Two-thirds (66.5%) of nonoverweight women and 48.9% of overweight women reported ever doing yoga, while 27.2% of nonoverweight women and 16.4% of overweight women practiced regularly (≥30 min/wk). Fewer men practiced yoga. Among young adults practicing regularly (n = 294), differences were identified in intensity, type, and location of yoga practice across weight status. Young adults who were overweight and practiced yoga regularly showed a nonsignificant 5-year decrease in their body mass index (-0.60 kg/m 2 ; P = .49), whereas those not practicing regularly had significant increases in their body mass index (+1.37 kg/m 2 ; P yoga was inversely associated with weight gain among both overweight and nonoverweight young adults practicing yoga regularly. Young adults of different body sizes practice yoga. Yoga was associated with less weight gain over time, particularly in overweight young adults. Practicing yoga on a regular basis may help with weight gain prevention.

Design concepts and status of the Korean next generation reactor (KNGR)

International Nuclear Information System (INIS)

Cho, Sung Jae; Kim, Han Gon

1999-01-01

The national project to develop KNGR, a 4000 MWth evolutionary advanced light water reactor (ALWR), has been organized in three phases according to the development status in 1992. During the first phase, the top-tier design requirements and the design concepts to meet the requirements had been established. The project is currently in the second phase of which the major objective is to complete the basic design sufficient to confirm the plant safety. This paper describes the overall design concepts and status of the KNGR briefly which developed and/or being developed through the project. (author)

Improving the Status of Human and Material Resources in Public ...

African Journals Online (AJOL)

Improving the Status of Human and Material Resources in Public Primary School in Oyo States ... the Millennium Development Goals project in the State. ... libraries, well-equipped first aid centres, adequate electronically projected instructional ...

Application of microwave air plasma in the destruction of trichloroethylene and carbon tetrachloride at atmospheric pressure

Energy Technology Data Exchange (ETDEWEB)

Rubio, S.J., E-mail: f62rugas@uco.es [Departamento de Fisica, Campus de Rabanales, Edificio Einstein, Planta Baja, Universidad de Cordoba (Spain); Quintero, M.C.; Rodero, A. [Departamento de Fisica, Campus de Rabanales, Edificio Einstein, Planta Baja, Universidad de Cordoba (Spain)

2011-02-15

In this study, the destruction rate of a volatile waste destruction system based on a microwave plasma torch operating at atmospheric pressure was investigated. Atmospheric air was used to maintain the plasma and was introduced by a compressor, which resulted in lower operating costs compared to other gases such as argon and helium. To isolate the output gases and control the plasma discharge atmosphere, the plasma was coupled to a reactor. The effect of the gas flow rate, microwave power and initial concentration of compound on the destruction efficiency of the system was evaluated. In this study, trichloroethylene and carbon tetrachloride were used as representative volatile organic compounds to determine the destruction rate of the system. Based on the experimental results, at an applied microwave power less than 1000 W, the proposed system can reduce input concentrations in the ppmv range to output concentrations at the ppbv level. High air flow rates and initial concentrations produced energy efficiency values greater than 1000 g/kW h. The output gases and species present in the plasma were analysed by gas chromatography and optical emission spectroscopy, respectively, and negligible amounts of halogenated compounds resulting from the cleavage of C{sub 2}HCl{sub 3} and CCl{sub 4} were observed. The gaseous byproducts of decomposition consisted mainly of CO{sub 2}, NO and N{sub 2}O, as well as trace amounts of Cl{sub 2} and solid CuCl.

Application of microwave air plasma in the destruction of trichloroethylene and carbon tetrachloride at atmospheric pressure.

Science.gov (United States)

Rubio, S J; Quintero, M C; Rodero, A

2011-02-15

In this study, the destruction rate of a volatile waste destruction system based on a microwave plasma torch operating at atmospheric pressure was investigated. Atmospheric air was used to maintain the plasma and was introduced by a compressor, which resulted in lower operating costs compared to other gases such as argon and helium. To isolate the output gases and control the plasma discharge atmosphere, the plasma was coupled to a reactor. The effect of the gas flow rate, microwave power and initial concentration of compound on the destruction efficiency of the system was evaluated. In this study, trichloroethylene and carbon tetrachloride were used as representative volatile organic compounds to determine the destruction rate of the system. Based on the experimental results, at an applied microwave power less than 1000 W, the proposed system can reduce input concentrations in the ppmv range to output concentrations at the ppbv level. High air flow rates and initial concentrations produced energy efficiency values greater than 1000 g/kW h. The output gases and species present in the plasma were analysed by gas chromatography and optical emission spectroscopy, respectively, and negligible amounts of halogenated compounds resulting from the cleavage of C(2)HCl(3) and CCl(4) were observed. The gaseous byproducts of decomposition consisted mainly of CO(2), NO and N(2)O, as well as trace amounts of Cl(2) and solid CuCl. Copyright © 2010 Elsevier B.V. All rights reserved.

Folic acid and melatonin ameliorate carbon tetrachloride-induced hepatic injury, oxidative stress and inflammation in rats

Directory of Open Access Journals (Sweden)

Ebaid Hossam

2013-02-01

Full Text Available Abstract This study investigated the protective effects of melatonin and folic acid against carbon tetrachloride (CCl4-induced hepatic injury in rats. Oxidative stress, liver function, liver histopathology and serum lipid levels were evaluated. The levels of protein kinase B (Akt1, interferon gamma (IFN-γ, programmed cell death-receptor (Fas and Tumor necrosis factor-alpha (TNF-α mRNA expression were analyzed. CCl4 significantly elevated the levels of lipid peroxidation (MDA, cholesterol, LDL, triglycerides, bilirubin and urea. In addition, CCl4 was found to significantly suppress the activity of both catalase and glutathione (GSH and decrease the levels of serum total protein and HDL-cholesterol. All of these parameters were restored to their normal levels by treatment with melatonin, folic acid or their combination. An improvement of the general hepatic architecture was observed in rats that were treated with the combination of melatonin and folic acid along with CCl4. Furthermore, the CCl4-induced upregulation of TNF-α and Fas mRNA expression was significantly restored by the three treatments. Melatonin, folic acid or their combination also restored the baseline levels of IFN-γ and Akt1 mRNA expression. The combination of melatonin and folic acid exhibited ability to reduce the markers of liver injury induced by CCl4 and restore the oxidative stability, the level of inflammatory cytokines, the lipid profile and the cell survival Akt1 signals.

14 CFR 152.325 - Financial status report: Airport planning.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Financial status report: Airport planning... agency conducting a project for airport system planning shall submit a financial status report on a form... TRANSPORTATION (CONTINUED) AIRPORTS AIRPORT AID PROGRAM Accounting and Reporting Requirements § 152.325 Financial...

Military Family Coping Project - Phase II

Science.gov (United States)

2015-05-01

Anxiety, Life Satisfaction , Addiction, Trauma 4 The Military Family Coping Project reflects two phases. The first consisted of a series of focus...need for and guided the work of the Military Family Coping Project Phase II funded by TATRC. The Military Family Coping Project Phase II was...solidarity. For the purposes of family functioning analyses, married and unmarried soldiers were analyzed separately because marital status affects

Present status of research within the International Project

International Nuclear Information System (INIS)

Anon.

1975-01-01

The short report enumerates the studies which are now completed by the International Project in the Field of Food Irradiation and the studies to be continued. New feeding studies with irradiated fish, rice, spices and mangoes are performed. (MG) [de

Design status of the Delfi-Next nanosatellite project

NARCIS (Netherlands)

Bouwmeester, J.; Brouwer, G.F.; Gill, E.K.A.; Monna, G.L.E.; Rotteveel, J.

2010-01-01

Delfi-Next is the second project within the Delfi nanosatellite development program of Delft University of Technology. It will provide students hands-on experience, facilitate technology demonstration for innovative miniaturized space technology from the Dutch space sector and allow advancements in

Fossil energy waste management. Technology status report

Energy Technology Data Exchange (ETDEWEB)

Bossart, S.J.; Newman, D.A.

1995-02-01

This report describes the current status and recent accomplishments of the Fossil Energy Waste Management (FE WM) projects sponsored by the Morgantown Energy Technology Center (METC) of the US Department of Energy (DOE). The primary goal of the Waste Management Program is to identify and develop optimal strategies to manage solid by-products from advanced coal technologies for the purpose of ensuring the competitiveness of advanced coal technologies as a future energy source. The projects in the Fossil Energy Waste Management Program are divided into three types of activities: Waste Characterization, Disposal Technologies, and Utilization Technologies. This technology status report includes a discussion on barriers to increased use of coal by-products. Also, the major technical and nontechnical challenges currently being addressed by the FE WM program are discussed. A bibliography of 96 citations and a list of project contacts is included if the reader is interested in obtaining additional information about the FE WM program.

Controlled Ecological Life Support System Breadboard Project - 1988

Science.gov (United States)

Knott, W. M.

1989-01-01

The Controlled Ecological Life Support System (CELSS) Breadboard Project, NASA's effort to develop the technology required to produce a functioning bioregenerative system, is discussed. The different phases of the project and its current status are described. The relationship between the project components are shown, and major project activities for fiscal years 1989-1993 are listed. The biomass production chamber to be used by the project is described.

Buff book 1: status summary report, water reactor safety research

International Nuclear Information System (INIS)

1980-01-01

This Management Report, to provide information for monitoring and controlling the progress of LWR Safety Research Projects Associated with the Office of Nuclear Regulatory Research and other agencies and organizations engaged in nuclear safety research. It utilizes data pertaining to project schedules, cost, and status which have been integrated into a network-based management information system, The purpose of this publication is to provide a vehicle for review of the current status and overall progress of the safety Research Program from a managerial point of view

About Nano-JASMINE Satellite System and Project Status

Science.gov (United States)

Sako, Nobutada

Intelligent Space Systems Laboratory, The University of Tokyo (ISSL) and National Astronomical Observatory of Japan (NAO) have been developing a small infrared astrometry satellite named “Nano-JASMINE”. The satellite size is about 50cm cubic and 20kg, which plays a pre-cursor role of JASMINE Project which is programmed by NAO and JAXA. In addition, since there has been only one astrometry satellite HIPPARCOS by ESA in the past, Nano-JASMINE is also expected to achieve certain scientific results in the field of astrometry. In this project, ISSL aims to develop new advanced small satellite bus system whose performance is comparable to that of 100-500kg sized satellites, including attitude stability of 1 arc-second and thermal stability of the mission subsystem of 1 mK. This paper overviews the Nano-JASMINE bus system with emphasis on attitude and thermal control systems.

IGCC demonstration project status combustion engineering IGCC repowering project

International Nuclear Information System (INIS)

Glamuzina, R.W.; Allen, R.J.; Peletz, L.J.

1993-01-01

This demonstration project was originally conceived as the repowering of an existing plant facility, the Lakeside Station in Springfield, Illinois. The Owner, City Water, Light and Power (CWL ampersand P), has removed five of the original boilers and three of the original turbines. The buildings have had asbestos insulation removed and the interiors have been prepared for the construction of a single Integrated Gasification Combined Cycle (IGCC) process train that will generate a net output of 60 megawatts. The plant consists of a combined cycle (gas turbine, heat recovery steam generator, steam turbine) power train located in the existing buildings and a coal gasification system in a new building. The gasification system contains ABB CE's air-blown, entrained flow, two stage gasifier, an advanced hot gas desulfurization system by General Electric Environmental Services, Inc. and the necessary auxiliary systems. The plant is designed to produce a nominal 60 MW net output with an ambient air temperature of 95 degrees F and a cooling water temperature of 89 degrees F on either Natural Gas or Illinois No. 5 coal

Catalog of Investment Projects in Bulgaria

Energy Technology Data Exchange (ETDEWEB)

NONE

2011-10-15

This catalog includes information about 129 potential investment projects in Bulgaria and was developed by a team of experts from InvestBulgaria Agency in cooperation with municipalities and private companies. The document presents in brief general facts about the regions in Bulgaria. Projects are divided into the following categories: Tourism, Manufacturing, Urban Planning, Real Estate, Environment and renewable energy sources, Commerce, and Innovative and creative projects. The catalog provides detailed information about each project such as: status of the project, location, ownership, infrastructure, estimated value, contact information, etc.

Addressing the technical capacity constraints on community-based labour intensive road projects - a case study of the Amadiba road project

CSIR Research Space (South Africa)

Lachman, A

2006-09-01

Full Text Available effect. 3. AIMS AND OBJECTIVE OF THE PAPER The main aim of this paper is to discuss the technical capacity constraints experienced on the Amadiba Road Project and to outline the measures taken to address them. Some of the objectives of this paper... are to: � Highlight the socioeconomic status of the community � Highlight the capacity needed on the project � Discuss some of the capacity building issues � Highlight the current state of the community 4. SOCIOECONOMIC STATUS OF THE AMADIBA...

Integrated process status overview

International Nuclear Information System (INIS)

Gertman, D.I.; Gaudio, P. Jr.

1986-01-01

This report summarizes findings to date with the IPSO, a large plant status overview currently under development at the OECD Halden Reactor Project. As part of a joint Halden and Combustion Engineering project, the overview is being tested in part to determine whether the large screen overview concept being entertained for use in the nuclear power plant (NPP) industry will facilitate operator performance. To this end an interactive simulation technique was used to establish a proof-of-principle test for the IPSO. Process control, operations, and human factors experts at Halden participated in the test and evaluation

Status of the IEEE P896 Future Backplane Bus

International Nuclear Information System (INIS)

Gustavson, D.B.

1983-10-01

The IEEE P896 Future Backplane Bus project has been influenced by and has influenced FASTBUS and several other contemporary bus designs. This paper summarizes the current status of that project, which is directed toward the needs of modern 32-bit microprocessor systems with multiple processors. Some of the technology developed for P896 will be important for future non-ECL implementations of FASTBUS and other buses. In particular, new bus drivers and receivers should greatly improve the performance and reliability of backplane buses and cable buses. The current status of the P896 serial bus is also summarized

HESYRL control system status

International Nuclear Information System (INIS)

Yao Chihyuan

1992-01-01

HESYRL synchrotron radiation storage ring was completed in 1989 and has been in commissioning since then. Now it has met its design specification and is ready for synchrotron light experiments. Control system of the project was completed in 1989 and some modifications were made during commissioning. This paper describes its present configuration, status and upgrading plan. (author)

Effectiveness of enterosgel usage in the conditions of simultaneous destruction of rats by karbofos and carbon tetrachloride

Directory of Open Access Journals (Sweden)

L. А. Boyko

2014-10-01

Full Text Available The aim of our study was to examine the effectiveness of the enterosgel sorbent in the terms of simultaneous destruction of rats by karbofos and carbon tetrachloride. Experiments were carried out on white rats weighing 175–200 g, which were kept on a standard diet. Karbofos was administered intragastrically on daily basis in the aqueous solution at the rate of 20 mg/kg of the body weight, which is 1/10 of the LD50. Carbon tetrachloride was administered intraperitoneally, twice a day in the form of a 50% oil solution at a dose of 1.0 ml/kg of animal. Animals received enterosgel daily by intragastric way at the rate of 120 mg/kg of body weight. The activity of free radical processes in rats was assessed by thiobarbituric acid content – active products (TBA-AP in serum, liver and heart homogenates. Level of endogenous intoxication was determined by the content of average weight molecules (AWM in serum and liver homogenate. The degree of cytolysis of hepatocytes was assessed by the activity of alanine and aspartate aminotransferase (AlAT, AsAT, alkaline phosphatase (ALP in serum, liver and heart homogenates. The degree of damage of the nervous system was studied by the activity of acetylcholinesterase (AChE in serum and liver homogenate. Content of TBA-AP in serum, liver and myocardium increased throughout the period of study. Reduction of TBA-AP was observed in studied tissues after applying of enterosgel sorbent in the affected body. After the defeat by toxicants we showed significant increase of fraction of AM1 (chain aminoacids dominate and AM2 (aromatic aminoacids dominate in serum and liver of experimental rats throughout the experiment. Enterosgel showed a positive effect on this index, reducing the content of MSM molecules. Due to toxic effects of endogenous and exogenous toxins in cells degradation and changing the permeability of plasma membranes of hepatocytes was observed as evidenced by the increased activity of both AlAT and As

The VIRGO project

International Nuclear Information System (INIS)

Mours, B.

1993-11-01

The VIRGO detector is a 3 km length interferometer antenna with a design sensitivity aiming at the direct observation of gravitational waves. The expected gravitational wave sources are discussed, then the French-Italian experiment and the status of the project are described. (author) 4 refs., 4 figs

Darmstadt Linear Accelerator (DALINAC) Research Laboratory. Status report - July 1988

International Nuclear Information System (INIS)

Anon.

1988-07-01

The status of the DALINAC project is reviewed. The accelerator and the experimental facilities are described, and a free-electron laser project is considered. Furthermore, experiments on inelastic electron scattering on nuclei and atomic systems are listed. (HSI)

ATLAS construction status

International Nuclear Information System (INIS)

Jenni, P.

2006-01-01

The ATLAS detector is being constructed at the LHC, in view of a data-taking startup in 2007. This report concentrates on the progress and the technical challenges of the detector construction, and summarizes the status of the work as of August 2004. The project is on track to allow the highly motivated ATLAS Collaboration to enter into a new exploratory domain of high-energy physics in 2007. (author)

FASTBUS software status

International Nuclear Information System (INIS)

Gustavson, D.B.

1980-10-01

Computer software will be needed in addition to the mechanical, electrical, protocol and timing specifications of the FASTBUS, in order to facilitate the use of this flexible new multiprocessor and multisegment data acquisition and processing system. Software considerations have been important in the FASTBUS design, but standard subroutines and recommended algorithms will be needed as the FASTBUS comes into use. This paper summarizes current FASTBUS software projects, goals and status

Transformation of carbon tetrachloride and chloroform by trichloroethene respiring anaerobic mixed cultures and supernatant.

Science.gov (United States)

Vickstrom, Kyle E; Azizian, Mohammad F; Semprini, Lewis

2017-09-01

Carbon tetrachloride (CT) and chloroform (CF) were transformed in batch reactor experiments conducted with anaerobic dechlorinating cultures and supernatant (ADC + S) harvested from continuous flow reactors. The Evanite (EV) and Victoria/Stanford (VS) cultures, capable of respiring trichloroethene (TCE), 1,2-cis-dichloroethene (cDCE), and vinyl chloride (VC) to ethene (ETH), were grown in continuous flow reactors receiving an influent feed of saturated TCE (10 mM; 60 mEq) and formate (45 mM; 90 mEq) but no CT or CF. Cells and supernatant were harvested from the chemostats and inoculated into batch reactors at the onset of each experiment. CT transformation was complete following first order kinetics with CF, DCM and CS 2 as the measurable transformation products, representing 20-40% of the original mass of CT, with CO 2 likely the unknown transformation product. CF was transformed to DCM and likely CO 2 at an order of magnitude rate lower than CT, while DCM was not further transformed. An analytical first order model including multiple key reactions effectively simulated CT transformation, product formation and transformation, and provided reasonable estimates of transformation rate coefficients. Biotic and abiotic treatments indicated that CT was mainly transformed via abiotic processes. However, the presence of live cells was associated with the transformation of CF to DCM. In biotic tests both TCE and CT were simultaneously transformed, with TCE transformed to ETH and approximately 15-53% less CF formed via CT transformation. A 14-day exposure to CF (CF max  = 1.4 μM) reduced all rates of chlorinated ethene respiration by a factor of 10 or greater. Copyright © 2017 Elsevier Ltd. All rights reserved.

Present status of the KISS project

Science.gov (United States)

Miyatake, H.; Wada, M.; Watanabe, X. Y.; Hirayama, Y.; Schury, P.; Ahmed, M.; Ishiyama, H.; Jeong, S. C.; Kakiguchi, Y.; Kimura, S.; Moon, J. Y.; Mukai, M.; Oyaizu, M.; Park, J. H.

2018-04-01

KISS project aims at finding an astrophysical condition for synthesizing r-process heavy element isotopes, which are characterized as the third peak in the solar abundance pattern. This is an experimental challenge in nuclear physics to measure ground and isomeric state properties of unknown nuclei around the region of N=126 isotones. So far we have constructed and developed new type of mass separation system, KISS (KEK Isotope Separation System) and performed measurements of lifetimes and hyperfine structures of some platinum and iridium neutron-rich radioactive isotopes by applying multi-nucleon transfer reactions and in-gas laser ionization and spectroscopy (IGLIS) methods. In this report, recent physics results, updated KISS performance, and future's research plan including a challenge of a systematic mass measurement with MRTOF (Multi-Reflection Time-Of-Flight mass spectrograph) are presented.

Present status and physics prospects of SSC

International Nuclear Information System (INIS)

Sugimoto, Shojiro

1990-01-01

Physics prospects of Superconducting Super Collider (SSC) are discussed, referring to other coming colliders. In addition, the present status of the SSC project and detector proposals for the experiments are described. (author)

Federated product data management in multi company projects

NARCIS (Netherlands)

Pels, H.J.; Elmaraghy, H.A.; Elmaraghy, W.H.

2005-01-01

An approach for enabling concurrent engineering between companies by providing a proper collaboration platform, as developed in the VIDOP project is proposed. Apart from security, information status is an important element of trust. However, status-coding schemes differ much between companies and

Synthesis, growth, and structural, optical, mechanical, electrical properties of a new inorganic nonlinear optical crystal: Sodium manganese tetrachloride (SMTC

Directory of Open Access Journals (Sweden)

M. Packiya raj

2017-01-01

Full Text Available A new inorganic nonlinear optical single crystal of sodium manganese tetrachloride (SMTC has been successfully grown from aqueous solution using the slow evaporation technique at room temperature. The crystals obtained using the aforementioned method were characterized using different techniques. The crystalline nature of the as-grown crystal of SMTC was analyzed using powder X-ray diffraction. Single-crystal X-ray diffraction revealed that the crystal belongs to an orthorhombic system with non-centrosymmetric space group Pbam. The optical transmission study of the SMTC crystal revealed high transmittance in the entire UV–vis region, and the lower cut-off wavelength was determined to be 240 nm. The mechanical strength of the as-grown crystal was estimated using the Vickers microhardness test. The second harmonic generation (SHG efficiency of the crystal was measured using Kurtz's powder technique, which indicated that the crystal has a nonlinear optical (NLO efficiency that is 1.32 times greater than that of KDP. The dielectric constant and dielectric loss of the compound were measured at different temperatures with varying frequencies. The photoconductivity study confirmed that the title compound possesses a negative photoconducting nature. The growth mechanism and surface features of the as-grown crystals were investigated using chemical etching analysis.

Concentrating Solar Power Projects - Khi Solar One | Concentrating Solar

Science.gov (United States)

Power | NREL Khi Solar One This page provides information on Khi Solar One, a concentrating solar power (CSP) project, with data organized by background, parcipants and power plant configuration . Status Date: February 8, 2016 Project Overview Project Name: Khi Solar One Country: South Africa Location

Oral administration of Saccharomyces boulardii ameliorates carbon tetrachloride-induced liver fibrosis in rats via reducing intestinal permeability and modulating gut microbial composition.

Science.gov (United States)

Li, Ming; Zhu, Lin; Xie, Ao; Yuan, Jieli

2015-02-01

To investigate the effects of orally administrated Saccharomyces boulardii (S. boulardii) on the progress of carbon tetrachloride (CCl4)-induced liver fibrosis, 34 male Wistar rats were randomly divided into four experimental groups including the control group (n = 8), the cirrhotic group (n = 10), the preventive group (n = 8), and the treatment group (n = 8). Results showed that the liver expression levels of collagen, type I, alpha 1 (Col1A1), alpha smooth muscle actin (αSMA), transforming growth factor beta (TGF-β) and the serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and malondialdehyde (MDA) increased significantly in cirrhotic rats compared with control and decreased by S. boulardii administration. Treatment of S. boulardii also attenuated the increased endotoxin levels and pro-inflammatory cytokines in CCl4-treated rats. And, these were associated with the changes of intestinal permeability and fecal microbial composition. Our study suggested that oral administration of S. boulardii can promote the liver function of CCl4-treated rats, and the preventive treatment of this probiotic yeast may decelerate the progress of liver fibrosis.

Hepatoprotective activity of the neem-based constituent azadirachtin-A in carbon tetrachloride intoxicated Wistar rats.

Science.gov (United States)

Baligar, N S; Aladakatti, R H; Ahmed, Mukhtar; Hiremath, M B

2014-04-01

The aim of this study was to investigate the hepatoprotective role of azadirachtin-A in carbon tetrachloride (CCl4) induced hepatotoxicity in rats. The group allotment for the animals used in the hepatoprotective study included a vehicle treatment group, CCl4 (1 mL · (kg body mass)(-1)) treatment group, silymarin (100 μg · (kg body mass)(-1) · day(-1)) + CCl4 treatment group, and groups treated with different doses of azadirachtin-A (100 or 200 μg · (kg body mass)(-1) · day(-1)) + CCl4. On the 9th day, blood was obtained for measuring the biochemical parameters, and liver tissue was obtained for pathological examination. The acute toxicity test with azadirachtin-A (500, 1000, or 2000 μg · (kg body mass)(-1)) indicated no mortality after 14 days of treatment; further, there was no change in behavior, food consumption, or organ mass. However with the higher dose, some hematological parameters showed changes. Hepatoprotective studies revealed that the CCl4 treatment group exhibited a decrease in total protein and albumin levels, whereas a significant increase in BUN, AST, ALT, and ALP levels were noticed compared with the vehicle-treated control, indicating that there was liver damage caused by CCl4. Histology and ultrastructure study confirmed that pretreatment with azadirachtin-A dose-dependently reduced hepatocellular necrosis and, therefore, protected the liver against toxicity caused by CCl4. The results from this study indicate that pretreatment with azadirachtin-A at the higher dose levels, moderately restores the rat liver to normal. This study confirms that azadirachtin-A possesses greater hepatoprotective action; however, the effective concentration needs to be determined.

Final ITER CTA project board meeting

International Nuclear Information System (INIS)

Vlasenkov, V.

2003-01-01

The final ITER CTA Project Board Meeting (PB) took place in Barcelona, Spain on 8 December 2002. The PB took notes of the comments concerning the status of the International Team and the Participants Teams, including Dr. Aymar's report 'From ITER to a FUSION Power Reactor' and the assessment of the ITER project cost estimate

Commercial Supersonics Technology Project - Status of Airport Noise

Science.gov (United States)

Bridges, James

2016-01-01

The Commercial Supersonic Technology Project has been developing databases, computational tools, and system models to prepare for a level 1 milestone, the Low Noise Propulsion Tech Challenge, to be delivered Sept 2016. Steps taken to prepare for the final validation test are given, including system analysis, code validation, and risk reduction testing.

Human endometrial regenerative cells alleviate carbon tetrachloride-induced acute liver injury in mice

Directory of Open Access Journals (Sweden)

Shanzheng Lu

2016-10-01

Full Text Available Abstract Background The endometrial regenerative cell (ERC is a novel type of adult mesenchymal stem cell isolated from menstrual blood. Previous studies demonstrated that ERCs possess unique immunoregulatory properties in vitro and in vivo, as well as the ability to differentiate into functional hepatocyte-like cells. For these reasons, the present study was undertaken to explore the effects of ERCs on carbon tetrachloride (CCl4–induced acute liver injury (ALI. Methods An ALI model in C57BL/6 mice was induced by administration of intraperitoneal injection of CCl4. Transplanted ERCs were intravenously injected (1 million/mouse into mice 30 min after ALI induction. Liver function, pathological and immunohistological changes, cell tracking, immune cell populations and cytokine profiles were assessed 24 h after the CCl4 induction. Results ERC treatment effectively decreased the CCl4-induced elevation of serum alanine aminotransferase (ALT and aspartate aminotransferase (AST activities and improved hepatic histopathological abnormalities compared to the untreated ALI group. Immunohistochemical staining showed that over-expression of lymphocyte antigen 6 complex, locus G (Ly6G was markedly inhibited, whereas expression of proliferating cell nuclear antigen (PCNA was increased after ERC treatment. Furthermore, the frequency of CD4+ and CD8+ T cell populations in the spleen was significantly down-regulated, while the percentage of splenic CD4+CD25+FOXP3+ regulatory T cells (Tregs was obviously up-regulated after ERC treatment. Moreover, splenic dendritic cells in ERC-treated mice exhibited dramatically decreased MHC-II expression. Cell tracking studies showed that transplanted PKH26-labeled ERCs engrafted to lung, spleen and injured liver. Compared to untreated controls, mice treated with ERCs had lower levels of IL-1β, IL-6, and TNF-α but higher level of IL-10 in both serum and liver. Conclusions Human ERCs protect the liver from acute injury

MIPAS ESA v7 carbon tetrachloride data: distribution, trend and atmospheric lifetime estimation

Science.gov (United States)

Valeri, M.; Barbara, F.; Boone, C. D.; Ceccherini, S.; Gai, M.; Maucher, G.; Raspollini, P.; Ridolfi, M.; Sgheri, L.; Wetzel, G.; Zoppetti, N.

2017-12-01

Carbon tetrachloride (CCl4) is a strong ozone-depleting atmospheric gas regulated by the Montreal protocol. Recently it received increasing interest due to the so called "mystery of CCl4": it was found that its atmospheric concentration at the surface declines with a rate significantly smaller than its lifetime-limited rate. Indeed there is a discrepancy between atmospheric observations and the estimated distribution based on the reported production and consumption. Michelson Interferometer for Passive Atmospheric Sounding (MIPAS) measurements are used to estimate CCl4 distributions, its trend, and atmospheric lifetime in the upper troposphere / lower stratosphere (UTLS) region. In particular, here we use MIPAS product generated with Version 7 of the Level 2 algorithm operated by the European Space Agency. The CCl4 distribution shows features typical of long-lived species of anthropogenic origin: higher concentrations in the troposphere, decreasing with altitude due to the photolysis. We compare MIPAS CCl4 data with independent observations from Atmospheric Chemistry Experiment - Fourier Transform Spectrometer (ACE - FTS) and stratospheric balloon version of MIPAS (MIPAS-B). The comparison shows a general good agreement between the different datasets. CCl4 trends are evaluated as a function of both latitude and altitude: negative trends (-10/ -15 pptv/decade, -10/ -30 %/decade) are found at all latitudes in the UTLS, apart from a region in the Southern mid-latitudes between 50 and 10 hPa where the trend is slightly positive (5/10 pptv/decade, 15/20 %/decade). At the lowest altitudes sounded by the MIPAS scan we find trend values consistent with those determined on the basis of the Advanced Global Atmospheric Gases Experiment (AGAGE) and the National Oceanic and Atmospheric Administration / Earth System Research Laboratory / Halocarbons and other Atmospheric Trace Species (NOAA / ESRL / HATS) networks. CCl4 global average lifetime of 47(39 - 61) years has been

Steam generator replacement project in 2000

International Nuclear Information System (INIS)

Cerjak, J.; Holz, R.; Haus, J.; Gloaguen, C.

1999-01-01

NE Krsko has awarded the contract for the Steam Generator Replacement Project, which is one of the modernization projects in Krsko, to the Consortium of Siemens / Framatome in February 1998. This paper deals with the various aspects of the project: scope planning, engineering, preparation of modification packages for licensing, management, major techniques used, etc., showing also the status of the activities for the project which are scheduled to be performed in April through June 2000. The project is being performed on a turnkey basis, that means the Consortium is performing all engineering, preparation of the modification packages and site activities; NE Krsko is dealing with the licensing of the project.(author)

Exploring the joint effect of atmospheric pollution and socioeconomic status on selected health outcomes: an overview of the PAISARC project

International Nuclear Information System (INIS)

Bard, D; Laurent, O; Filleul, L; Havard, S; Deguen, S; Segala, C; Pedrono, G; Riviere, E; Schillinger, C; Rouil, L; Arveiler, D; Eilstein, D

2007-01-01

Health socioeconomic gradients are well documented in developed countries, but incompletely explained. A portion of these health inequalities may be explained by environmental exposures. The objective of PAISARC is to explore the relations between socioeconomic status, air pollution exposure and two selected health outcomes-asthma exacerbations and myocardial infarction-at the level of a small area. The study design is ecological, using data available from the national census, with the residential block (French IRIS, 2000 people on average, National Institute of Statistics-INSEE) as the statistical unit. The setting is the Greater Strasbourg metropolitan area (450 000 inhabitants) in eastern France. We first constructed a socioeconomic status index, using 1999 national census data and principal component analysis at the resolution of these census blocks. Air pollution data were then modeled at the same resolution on an hourly basis for the entire study period (2000-2005). Health data were obtained from various sources (local emergency networks, the local population-based coronary heart disease registry, health insurance funds) according to the health outcome. We present here the initial results and discuss the methodological approaches best suited for the forthcoming steps of our project

Biofuels: Project summaries

Energy Technology Data Exchange (ETDEWEB)

1994-07-01

The US DOE, through the Biofuels Systems Division (BSD) is addressing the issues surrounding US vulnerability to petroleum supply. The BSD goal is to develop technologies that are competitive with fossil fuels, in both cost and environmental performance, by the end of the decade. This document contains summaries of ongoing research sponsored by the DOE BSD. A summary sheet is presented for each project funded or in existence during FY 1993. Each summary sheet contains and account of project funding, objectives, accomplishments and current status, and significant publications.

Multi-scale model of the ionosphere from the combination of modern space-geodetic satellite techniques - project status and first results

Science.gov (United States)

Schmidt, M.; Hugentobler, U.; Jakowski, N.; Dettmering, D.; Liang, W.; Limberger, M.; Wilken, V.; Gerzen, T.; Hoque, M.; Berdermann, J.

2012-04-01

Near real-time high resolution and high precision ionosphere models are needed for a large number of applications, e.g. in navigation, positioning, telecommunications or astronautics. Today these ionosphere models are mostly empirical, i.e., based purely on mathematical approaches. In the DFG project 'Multi-scale model of the ionosphere from the combination of modern space-geodetic satellite techniques (MuSIK)' the complex phenomena within the ionosphere are described vertically by combining the Chapman electron density profile with a plasmasphere layer. In order to consider the horizontal and temporal behaviour the fundamental target parameters of this physics-motivated approach are modelled by series expansions in terms of tensor products of localizing B-spline functions depending on longitude, latitude and time. For testing the procedure the model will be applied to an appropriate region in South America, which covers relevant ionospheric processes and phenomena such as the Equatorial Anomaly. The project connects the expertise of the three project partners, namely Deutsches Geodätisches Forschungsinstitut (DGFI) Munich, the Institute of Astronomical and Physical Geodesy (IAPG) of the Technical University Munich (TUM) and the German Aerospace Center (DLR), Neustrelitz. In this presentation we focus on the current status of the project. In the first year of the project we studied the behaviour of the ionosphere in the test region, we setup appropriate test periods covering high and low solar activity as well as winter and summer and started the data collection, analysis, pre-processing and archiving. We developed partly the mathematical-physical modelling approach and performed first computations based on simulated input data. Here we present information on the data coverage for the area and the time periods of our investigations and we outline challenges of the multi-dimensional mathematical-physical modelling approach. We show first results, discuss problems

Protective effect of ethyl acetate fraction of Rhododendron arboreum flowers against carbon tetrachloride-induced hepatotoxicity in experimental models.

Science.gov (United States)

Verma, Neeraj; Singh, Anil P; Amresh, G; Sahu, P K; Rao, Ch V

2011-05-01

To evaluate the hepatoprotective potential of ethyl acetate fraction of Rhododendron arboreum (Family: Ericaceae) in Wistar rats against carbon tetrachloride (CCl(4))-induced liver damage in preventive and curative models. Fraction at a dose of 100, 200, and 400 mg/kg was administered orally once daily for 14 days in CCl(4)-treated groups (II, III, IV, V and VI). The serum levels of glutamic oxaloacetic transaminase (SGOT), glutamate pyruvate transaminase (SGPT), alkaline phosphatase (SALP), γ-glutamyltransferase (γ -GT), and bilirubin were estimated along with activities of glutathione S-transferase (GST), glutathione reductase, hepatic malondialdehyde formation, and glutathione content. The substantially elevated serum enzymatic activities of SGOT, SGPT, SALP, γ-GT, and bilirubin due to CCl(4) treatment were restored toward normal in a dose-dependent manner. Meanwhile, the decreased activities of GST and glutathione reductase were also restored toward normal. In addition, ethyl acetate fraction also significantly prevented the elevation of hepatic malondialdehyde formation and depletion of reduced glutathione content in the liver of CCl(4)-intoxicated rats in a dose-dependent manner. Silymarin used as standard reference also exhibited significant hepatoprotective activity on post-treatment against CCl(4)-induced hepatotoxicity in rats. The biochemical observations were supplemented with histopathological examination of rat liver sections. The results of this study strongly indicate that ethyl acetate fraction has a potent hepatoprotective action against CCl(4)-induced hepatic damage in rats.

Pengaruh taburia terhadap status anemia dan status gizi balita gizi kurang

Directory of Open Access Journals (Sweden)

Wahyuni Kunayarti

2014-07-01

Full Text Available Background: Micronutrient deficiency seriously contributes to child morbidity and mortality. The need for micronutrient can be fulfilled from food, fortified food, and direct supplementation. Taburia is multivitamin multimineral that is aimed to meet the need for micronutrient of undernourished under-fives and to prevent the increased prevalence of undernourishment. It is necessary efficacy and effectiveness study of Taburia to anemia and nutritional status of undernourished under fives of 24-55 months. Objective: To identify the effect of Taburia supplementation to anemia and nutrition status of under fives at District of Lombok Timur. Method: The study was experimental with prospective cohort study design carried out at District of Lombok Timur, Province of Nusa Tenggara Barat. The subject of the study was undernourished under fives at the area of Nutrition Improvement Community through Empowerment (NICE project. The independent variables were Taburia and biscuits; the dependent variables were anemia and nutrition status; and the external variables were the intake of energy, protein, vitamin A, vitamin C, Fe, and zinc. Data analysis used ANOVA and paired t-test. Results: There was a significant difference in the average level of hemoglobin of the subject after the intervention, either in taburia group, biscuit group, or taburia+biscuit group (p<0.05. There was the difference in average weight after intervention in the three groups (p<0.05. There was no significant difference in the average level of hemoglobin and the average level of weight between biscuit group and Taburia+biscuit group. There was a change in anemia status from anemia to nonanemia; the highest was in Taburia group, i.e. 96%; and better nutrition status at the end of the experiment occurred at Taburia+biscuit group from emaciated to normal (100%. Conclusion: Taburia supplementation could increase anemia status. Micronutrient supplementation was needed to increase nutrition

Protective effect of a coffee preparation (Nescafe pure) against carbon tetrachloride-induced liver fibrosis in rats.

Science.gov (United States)

Shi, Hongyang; Dong, Lei; Zhang, Yong; Bai, Yanhua; Zhao, Juhui; Zhang, Li

2010-06-01

We examined the effects of a coffee preparation on liver fibrosis induced by carbon tetrachloride (CCl(4)) and explored the possible mechanisms. Rats were divided randomly into four groups: control, CCl(4), and two coffee preparation groups. Except for the control group, liver fibrosis was induced in male Sprague-Dawley (SD) rats by subcutaneous injection with 40% CCl(4) twice a week for 8 weeks. At the same time, a coffee preparation (300 mg/kg and 150 mg/kg) was administered to the two coffee preparation groups intragastrically once daily. Upon pathological examination, a coffee preparation treatment significantly reduced liver damage and symptoms of liver fibrosis. The mRNA expression of collagen I, collagen III, bcl-2, vascular endothelial growth factor (VEGF) and transforming growth factor-beta1 (TGF-beta1) were markedly increased by CCl(4) treatment but suppressed by a coffee preparation treatment. Whereas compared with the CCl(4) group, the mRNA expression of Bax was increased in the coffee preparation group. The protein expression of Bax and bcl-2 were confirmed by western blot. Intragastric administration of a coffee preparation reduced the protein expression of alpha-smooth muscle actin (alpha-SMA) and the glucose-regulated proteins (GRP) 78 and 94 in rats increased by CCl(4). Our data indicate that a coffee preparation can efficiently inhibit CCl(4)-induced liver fibrosis in rats. The coffee preparation may therefore be a potential functional food for preventing liver fibrosis. Copyright 2009 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

A nuclear power plant status monitor

International Nuclear Information System (INIS)

Chu, B.B.; Conradi, L.L.; Weinzimmer, F.

1986-01-01

Power plant operation requires decisions that can affect both the availability of the plant and its compliance with operating guidelines. Taking equipment out of service may affect the ability of the plant to produce power at a certain power level and may also affect the status of the plant with regard to technical specifications. Keeping the plant at a high as possible production level and remaining in compliance with the limiting conditions for operation (LCOs) can dictate a variety of plant operation and maintenance actions and responses. Required actions and responses depend on the actual operational status of a nuclear plant and its attendant systems, trains, and components which is a dynamic situation. This paper discusses an Electric Power Research Institute (EPRI) Research Project, RP 2508, the objective of which is to combine the key features of plant information management systems with systems reliability analysis techniques in order to assist nuclear power plant personnel to perform their functions more efficiently and effectively. An overview of the EPRI Research Project is provided along with a detailed discussion of the design and operation of the PSM portion of the project

DELSY project: status and development Dubna Electron Synchrotron

CERN Document Server

Balalykin, N; Bykovsky, V

2003-01-01

The DELSY (Dubna Electron Synchrotron) project is under development at the Joint Institute for Nuclear Research. It is based on an acceleration facility donated to the Joint Institute for Nuclear Research by the Institute for Nuclear and High Energy Physics (NIKHEF, Amsterdam). The NIKHEF accelerator facility consists of the linear electron accelerator MEA, which has an electron energy of 700 MeV, and the electron storage ring AmPS, with a maximum energy of 900 MeV and a beam current of 200 mA. There are three phases to the construction of the DELSY facility. Phase I will be accomplished with the construction of a complex of free-electron lasers covering continuously the spectrum from the far infrared down to the ultraviolet (approx 150 nm). Phase II will be accomplished with the commissioning of the storage ring DELSY. Complete commissioning of the DELSY project will take place after finishing Phase III, the construction of an X-ray free-electron laser. This phase is considered as the ultimate goal of the pr...

Environmental Assessment for Slope Stabilization Projects at Fort MacArthur, San Pedro, California

Science.gov (United States)

2012-01-01

effective in stabilizing slopes. The USAF and its consultants identified the most effective remedial measures that can be economically constructed within...consultants identified the most effective remedial measures that can be economically constructed with the physical and property boundary constraints...carbon tetrachloride, ammonia, hydrogen sulfide, hydrogen cyanide , and methane. The SCAB is not classified under CAAQS for any TACs (CARB 2011). EA

Eleusine indica L. possesses antioxidant activity and precludes carbon tetrachloride (CCl₄)-mediated oxidative hepatic damage in rats.

Science.gov (United States)

Iqbal, Mohammad; Gnanaraj, Charles

2012-07-01

The purpose of this study was to evaluate the ability of aqueous extract of Eleusine indica to protect against carbon tetrachloride (CCl₄)-induced hepatic injury in rats. The antioxidant activity of E. indica was evaluated using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay. The total phenolic content of E. indica was also determined. Biochemical parameters [e.g. alanine aminotransferase (ALT), aspartate aminotransferase (AST), malondialdehyde (MDA), glutathione (GSH), catalase, glutathione peroxidase, glutathione reductase, glutathione S-transferase and quinone reductase] were used to evaluate hepatic damage in animals pretreated with E. indica and intoxicated with CCl₄. CCl₄-mediated hepatic damage was also evaluated by histopathologically. E. indica extract was able to reduce the stable DPPH level in a dose-dependent manner. The half maximal inhibitory concentration (IC₅₀) value was 2350 μg/ml. Total phenolic content was found to be 14.9 ± 0.002 mg/g total phenolic expressed as gallic acid equivalent per gram of extract. Groups pretreated with E. indica showed significantly increased activity of antioxidant enzymes compared to the CCl₄-intoxicated group (p indica pretreatment (p indica-pretreated groups as compared to the CCl₄-intoxicated group. The protective effect of E. indica was further evident through decreased histopathological alterations in the liver. The results of our study indicate that the hepatoprotective effects of E. indica might be ascribable to its antioxidant and free radical scavenging property.

Status of the Munich compact core reactor project

International Nuclear Information System (INIS)

Boening, K.; Glaeser, W.; Meier, J.; Rau, G.; Roehrmoser, A.; Steichele, E.

1991-01-01

A new national, high performance research reactor is being planned in Munich which shall provide an unperturbed thermal neutron flux of about 8.10 14 cm -2 s -1 at only 20 MW power. This object can be achieved with the concept of a small, light water cooled 'compact core' situated in the center of a large heavy water moderator tank. In the first part of this paper an overview is given on the status of the necessary fuel enrichment is discussed. In becomes clear that the potential of the compact core concept can only be developed without compromises when using highly enriched uranium in combination with the new high density fuel. (orig.)

The EFF project status and the NEA nuclear data services

Energy Technology Data Exchange (ETDEWEB)

Henriksson, H. [OECD Nuclear Energy Agency, 12 Blvd des Iles, 92130 Issy-les-Moulineaux (France)], E-mail: henriksson@nea.fr; Batistoni, P. [Associazione Euratom-ENEA sulla Fusione, Via E. Fermi 45, 00044 Frascati (Italy); Fischer, U. [Association FZK-Euratom, Postfach 3640, 76021 Karlsruhe (Germany); Forrest, R. [Euratom/UKAEA Fusion Association, Culham Science Centre, Oxfordshire OX14 3DB (United Kingdom); Kodeli, I.; Nordborg, C. [OECD Nuclear Energy Agency, 12 Blvd des Iles, 92130 Issy-les-Moulineaux (France)

2007-10-15

The OECD Nuclear Energy Agency (NEA) Data Bank participates in the production of data and their distribution to users including the collection and validation as well as the distribution of the Joint Evaluated Fission and Fusion (JEFF) library. The JEFF project has evolved from two separate projects, namely the European Fusion File (EFF) and the Joint Evaluated File (JEF), with the release of JEFF-3.1, in May 2005. The NEA also provides tools for the EFF project, such as computer codes for nuclear energy and radiation physics applications. Of special interest for fusion applications are the integral experiments collected in the SINBAD database, with radiation shielding and dosimetry experiments including many fusion neutronics shielding experiments. In this paper an overview will be given of the NEA, and some examples of nuclear data services offered, such as the SINBAD database. JANIS, a display program evaluated and experimental data developed at the NEA will be mentioned briefly. The main emphasis will be given to the EFF project including the contents of the new JEFF-3.1 library, released in May 2005. Examples of recent work are given as well as a discussion on the forth-coming evaluation efforts among the EFF collaborators.

The EFF project status and the NEA nuclear data services

International Nuclear Information System (INIS)

Henriksson, H.; Batistoni, P.; Fischer, U.; Forrest, R.; Kodeli, I.; Nordborg, C.

2007-01-01

The OECD Nuclear Energy Agency (NEA) Data Bank participates in the production of data and their distribution to users including the collection and validation as well as the distribution of the Joint Evaluated Fission and Fusion (JEFF) library. The JEFF project has evolved from two separate projects, namely the European Fusion File (EFF) and the Joint Evaluated File (JEF), with the release of JEFF-3.1, in May 2005. The NEA also provides tools for the EFF project, such as computer codes for nuclear energy and radiation physics applications. Of special interest for fusion applications are the integral experiments collected in the SINBAD database, with radiation shielding and dosimetry experiments including many fusion neutronics shielding experiments. In this paper an overview will be given of the NEA, and some examples of nuclear data services offered, such as the SINBAD database. JANIS, a display program evaluated and experimental data developed at the NEA will be mentioned briefly. The main emphasis will be given to the EFF project including the contents of the new JEFF-3.1 library, released in May 2005. Examples of recent work are given as well as a discussion on the forth-coming evaluation efforts among the EFF collaborators

Status report for the Neutrino Platform NP05 (Baby MIND) experiment

CERN Document Server

Noah, E

2016-01-01

Report outlining progress by the Baby MIND collaboration since the October 2015 SPSC committee meeting. The Baby-MIND proposal was approved as NP05 with a clear recommendation to focus the project on the timely delivery of the magnetized downstream muon spectrometer for the Wagasci project. The measures taken to fullfill these recommendations are summarized. The status of the magnet design and procurement; of the detector modules, procurement of scintillator and module mechanics design; the status of the electronics and DAQ; and finally simulations and analysis are desctribed. The project schedule and milestones, the plans for test beam and the request for the use of the T9 test area are presented.

The Eurodif program. Present status of the project

International Nuclear Information System (INIS)

Besse, G.

1975-01-01

The reasons which led Eurodif to decide for the gaseous diffusion process and the benefits which such process offers for the present time are presented. The realization of the Eurodif project (description of the plant, time schedule of the realization, electric power supply, production time-schedule) is discussed. The Eurodif marketing policy, present and future, is reported [fr

Status of volcanism studies for the Yucca Mountain Site Characterization Project

Energy Technology Data Exchange (ETDEWEB)

Crowe, B.; Perry, F.; Murrell, M.; Poths, J.; Valentine, G.A. [Los Alamos National Lab., NM (United States); Wells, S. [Univ. of California, Riverside, CA (United States); Bowker, L.; Finnegan, K. [Univ. of Nevada, Las Vegas, NV (United States); Geissman, J.; McFadden, L.

1995-02-01

Chapter 1 introduces the volcanism issue for the Yucca Mountain site and provides the reader with an overview of the organization, content, and significant conclusions of this report. The risk of future basaltic volcanism is the primary topic of concern including both events that intersect a potential repository and events that occur near or within the waste isolation system of a repository. Chapter 2 describes the volcanic history of the Yucca Mountain region (YMR) and emphasizes the Pliocene and Quaternary volcanic record, the interval of primary concern for volcanic risk assessment. The Lathrop Wells volcanic center is described in detail because it is the youngest basalt center in the YMR. Chapter 3 describes the tectonic setting of the YMR and presents and assesses the significance of multiple alternative tectonic models. Geophysical data are described for the YMR and are used as an aid to understand the distribution of basaltic volcanic centers. Chapter 4 discusses the petrologic and geochemical features of basaltic volcanism in the YMR, the southern Great Basin and the Basin and Range province. The long time of activity and characteristic small volume of the Postcaldera basalt of the YMR result in one of the lowest eruptive rates in a volcanic field in the southwest United States. Chapter 5 summarizes current concepts of the segregation, ascent, and eruption of basalt magma. Chapter 6 summarizes the history of volcanism studies (1979 through early 1994), including work for the Yucca Mountain Site Characterization Project and overview studies by the state of Nevada and the Nuclear Regulatory Commission. Chapter 7 summarizes probabilistic volcanic hazard assessment using a three-part conditional probability model. Chapter 8 describes remaining volcanism work judged to be needed to complete characterization studies for the YMR. Chapter 9 summarizes the conclusions of this volcanism status report.

Status of volcanism studies for the Yucca Mountain Site Characterization Project

International Nuclear Information System (INIS)

Crowe, B.; Perry, F.; Murrell, M.; Poths, J.; Valentine, G.A.; Wells, S.; Bowker, L.; Finnegan, K.; Geissman, J.; McFadden, L.

1995-02-01

Chapter 1 introduces the volcanism issue for the Yucca Mountain site and provides the reader with an overview of the organization, content, and significant conclusions of this report. The risk of future basaltic volcanism is the primary topic of concern including both events that intersect a potential repository and events that occur near or within the waste isolation system of a repository. Chapter 2 describes the volcanic history of the Yucca Mountain region (YMR) and emphasizes the Pliocene and Quaternary volcanic record, the interval of primary concern for volcanic risk assessment. The Lathrop Wells volcanic center is described in detail because it is the youngest basalt center in the YMR. Chapter 3 describes the tectonic setting of the YMR and presents and assesses the significance of multiple alternative tectonic models. Geophysical data are described for the YMR and are used as an aid to understand the distribution of basaltic volcanic centers. Chapter 4 discusses the petrologic and geochemical features of basaltic volcanism in the YMR, the southern Great Basin and the Basin and Range province. The long time of activity and characteristic small volume of the Postcaldera basalt of the YMR result in one of the lowest eruptive rates in a volcanic field in the southwest United States. Chapter 5 summarizes current concepts of the segregation, ascent, and eruption of basalt magma. Chapter 6 summarizes the history of volcanism studies (1979 through early 1994), including work for the Yucca Mountain Site Characterization Project and overview studies by the state of Nevada and the Nuclear Regulatory Commission. Chapter 7 summarizes probabilistic volcanic hazard assessment using a three-part conditional probability model. Chapter 8 describes remaining volcanism work judged to be needed to complete characterization studies for the YMR. Chapter 9 summarizes the conclusions of this volcanism status report

Present status of the Zavratec remediation project

International Nuclear Information System (INIS)

Zeleznik, N.; Stepisnik, M.; Mele, I.

1997-01-01

In 1992 the responsibility for the remediation of the temporary storage of radioactive waste near Zavratec was assigned to the Agency for Radwaste Management. The project was divided into two phases. First, in a study, different options for remediation were considered. In the second phase, performed in 1996, the measurements, inventorying and repacking of radioactive waste were carried out. Simultaneously with these activities a programme for covering public relations was prepared. One of the results of the public relation campaign is also a 15-minute video film, which was prepared from documentary material recorded during remedial activities, and will be presented here. (author)

Antioxidant Activity of Grapevine Leaf Extracts against Oxidative Stress Induced by Carbon Tetrachloride in Cerebral Cortex, Hippocampus and Cerebellum of Rats

Directory of Open Access Journals (Sweden)

Mariane Wohlenberg

2014-04-01

Full Text Available In recent years, it has become increasingly important to study the beneficial properties of derivatives of grapes and grapevine. The objective of this study was to determine the antioxidant activity of Vitis labrusca leaf extracts, comparing conventional and organic grapevines, in different brain areas of rats. We used male Wistar rats treated with grapevine leaf extracts for a period of 14 days, and on the 15th day, we administered in half of the rats, mineral oil and the other half, carbon tetrachloride (CCl4. The animals were euthanized by decapitation and the cerebral cortex, hippocampus and cerebellum were removed to assess oxidative stress parameters and the activity of antioxidant enzymes. Lipid peroxidation levels (TBARS were unchanged. However, CCl4 induced oxidative damage to proteins in all tissues studied, and this injury was prevented by both extracts. Superoxide dismutase (SOD activity was increased by CCl4 in the cerebral cortex and decreased in other tissues. However, CCl4 increased catalase (CAT activity in the cerebellum and decreased it in the cerebral cortex. The SOD/CAT ratio was restored in the cerebellum by both extracts and only in the cerebral cortex by the organic extract.

Protective action of the immunomodulator ginsan against carbon tetrachloride-induced liver injury via control of oxidative stress and the inflammatory response

International Nuclear Information System (INIS)

Shim, Ji-Young; Kim, Mi-Hyoung; Kim, Hyung-Doo; Ahn, Ji-Yeon; Yun, Yeon-Sook; Song, Jie-Young

2010-01-01

The aim of the present study was to evaluate immunomodulator ginsan, a polysaccharide extracted from Panax ginseng, on carbon tetrachloride (CCl 4 )-induced liver injury. BALB/c mice were injected i.p. with ginsan 24 h prior to CCl 4 administration. Serum liver enzyme levels, histology, expression of antioxidant enzymes, and several cytokines/chemokines were subsequently evaluated. Ginsan treatment markedly suppressed the serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels, and hepatic histological necrosis increased by CCl 4 treatment. Ginsan inhibited CCl 4 induced lipid peroxidation through the cytochrome P450 2E1 (CYP2E1) downregulation. The hepatoprotective effect of ginsan was attributed to induction of anti-oxidant protein contents, such as superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPX) as well as restoration of the hepatic glutathione (GSH) concentration. The marked increase of proinflammatory cytokines (IL-1β, IFN-γ) and chemokines (MCP-1, MIP-2β, KC) in CCl 4 treated mice was additionally attenuated by ginsan, thereby preventing leukocyte infiltration and local inflammation. Our results suggest that ginsan effectively prevent liver injury, mainly through downregulation of oxidative stress and inflammatory response.

The Status of Topographic Mapping in the World a Unggim-Isprs Project 2012-2015

Science.gov (United States)

Konecny, G.; Breitkopf, U.; Radtke, A.

2016-06-01

In December 2011, UNGGIM initiated a cooperative project with ISPRS to resume the former UN Secretariat studies on the status of topographic mapping in the world, conducted between 1968 and 1986. After the design of a questionnaire with 27 questions, the UNGGIM Secretariat sent the questionnaires to the UN member states. 115 replies were received from the 193 member states and regions thereof. Regarding the global data coverage and age, the UN questionnaire survey was supplemented by data from the Eastview database. For each of the 27 questions, an interactive viewer was programmed permitting the analysis of the results. The authoritative data coverage at the various scale ranges has greatly increased between 1986 and 2012. Now, a 30 % 1 : 25 000 map data coverage and a 75 % 1 : 50 000 map data coverage has been completed. Nevertheless, there is still an updating problem, as data for some countries is 10 to 30 years old. Private Industry, with Google, Microsoft and Navigation system providers, have undertaken huge efforts to supplement authoritative mapping. For critical areas on the globe, MGCP committed to military mapping at 1 : 50 000. ISPRS has decided to make such surveys a sustainable issue by establishing a working group.

The Cost of Collaborating with Climbers of Status Hierarchies

DEFF Research Database (Denmark)

Andersen, Kristina Vaarst; Mors, Marie Louise; Jeppesen, Jacob

Status provides preferential access to resources, as well as favorable judgment, which in turn may lead to increases in performance. Prior work has established that such benefits even spill over between collaboration partners, thus allowing collaboration partners of high status individuals to bask...... individual performance. We argue that collaboration partners’ increased status may divert their allocation of effort and focus to other projects. This in turn may lead to a negative spillover effect for individual performance. These arguments are tested using unique data on scientists collaborating on papers...... in their reflected glory and enjoy status related benefits. Yet, we still know relatively little about the underlying mechanisms that affect how individual performance is affected by changes in the status of collaboration partners. In this paper, we analyze how collaboration partners’ status increase affects...

Reduction of carbon tetrachloride-induced rat liver injury by IRFI 042, a novel dual vitamin E-like antioxidant.

Science.gov (United States)

Campo, G M; Squadrito, F; Ceccarelli, S; Calò, M; Avenoso, A; Campo, S; Squadrito, G; Altavilla, D

2001-04-01

Carbon tetrachloride (CCl4 )-induced hepatotoxicity is likely the result of a CCl4 -induced free radical production which causes membrane lipid peroxidation and activation of transcription factors regulating both the TNF-alpha gene and the early-immediate genes involved in tissue regeneration. IRFI 042 is a novel vitamin E-like compound having a masked sulphydryl group in the aliphatic side chain. We studied the effect of IRFI 042 on CCl4 -induced liver injury. Liver damage was induced in male rats by an intraperitoneal injection of CCl4 (1 ml/kg in vegetal oil). Serum alanine aminotransferase (ALT) activity, liver malondialdehyde (MAL), hydroxyl radical formation (OH*), calculated indirectly by a trapping agent, hepatic reduced glutathione (GSH) concentration, plasma TNF-alpha, liver histology and hepatic mRNA levels for TNF-alpha were evaluated 48 h after CCl4 administration. Hepatic vitamin E (VE) levels were evaluated, in a separate group of animals, 2 h after CCl4 injection. A control group with vitamin E (100 mg/kg) was also treated in order to evaluate the differences versus the analogue treated groups. Intraperitoneal injection of carbon tetrachloride produced a marked increase in serum ALT activity (CCl4 = 404.61 +/- 10.33 U/L; Controls= 28.54 +/- 4.25 U/L), liver MAL (CCl4 = 0.67 +/- 0.16 nmol/mg protein; Controls= 0.13 +/- 0.06 nmol/mg protein), OH(7) levels assayed as 2,3-DHBA (CCl4 = 8.73 +/- 1.46 microM; Controls= 0.45 +/- 0.15 microM) and 2,5-DHBA (CCl4 = 24.61 +/- 3.32 microM; Controls= 2.75 +/- 0.93 microM), induced a severe depletion of GSH (CCl4 = 3.26 +/- 1.85 micromol/g protein; Controls= 17.82 +/- 3.13 micromol/g protein) and a marked decrease in VE levels (CCl4 = 5.67 +/- 1.22 nmol/g tissue; Controls= 13.47 +/- 3.21 nmol/g tissue), caused liver necrosis, increased plasma TNF-alpha levels (CCl4 = 57.36 +/- 13.24 IU/ml; Controls= 7.26 +/- 2.31 IU/ml) and enhanced hepatic mRNA for TNF-alpha (CCl4 = 19.22 +/- 4.38 a.u.; Controls= 0.76 +/- 0.36 a

Status and outlook of the CRYRING@ESR project

Energy Technology Data Exchange (ETDEWEB)

Geithner, W., E-mail: w.geithner@gsi.de; Andelkovic, Z.; Beck, D.; Bräuning, H.; Bräuning-Demian, A. [GSI Helmholtzzentrum für Schwerionenforschung (Germany); Danared, H. [European Spallation Source ESS (Sweden); Dimopoulou, C. [GSI Helmholtzzentrum für Schwerionenforschung (Germany); Engström, M. [Fysikum, Stockholm University (Sweden); Fedotova, S.; Gorda, O.; Herfurth, F.; Hess, R. [GSI Helmholtzzentrum für Schwerionenforschung (Germany); Källberg, A. [Fysikum, Stockholm University (Sweden); Kleffner, C.; Kotovskiy, N.; Kraus, I.; Lestinsky, M.; Litvinov, S.; Nolden, F.; Reiter, A. [GSI Helmholtzzentrum für Schwerionenforschung (Germany); and others

2017-11-15

Once operational, CRYRING@ESR will store and decelerate ions delivered by the experimental storage ring ESR at energies well below those of ESR. In addition to that, CRYRING@ESR has an electron cooler operating with an ultracold electron beam, allowing to provide cooled ion beams for precision experiments. These ions will be delivered to a broad range of experiments presently in preparation; either in-ring or extracted to a dedicated beamline for experiments. An overview and status report of the installation and commissioning of the CRYRING-@ESR storage ring for highly charged ions at the GSI Helmholtzzentrum für Schwerionenforschung is presented. The installation of this storage ring started in 2014 and was completing end of 2016, when this publication was written.

SSI's International Development Cooperation (SIUS). Status report, October 1998

International Nuclear Information System (INIS)

Szendroe, G.; Grapengiesser, S.; Johansson, Gunnar

1998-12-01

Until now the Swedish program for radiation protection work in Central and Eastern Europe, has since its start in 1992 been granted SEK 109.1 million by the Swedish government. The projects are assessed, planned and performed in close co-operation with partner organisations in Eastern Europe. This report presents a summary of the projects, their status, allocated funds and distribution over the countries and project areas. The presentation is updated as for October 1998

Waste Tank Vapor Characterization Project: Annual status report for FY 1995

International Nuclear Information System (INIS)

Ligotke, M.W.; Fruchter, J.S.; Huckaby, J.L.; Birn, M.B.; McVeety, B.D.; Evans, J.C. Jr.; Pool, K.H.; Silvers, K.L.; Goheen, S.C.

1995-11-01

This report compiles information collected during the Fiscal Year 1995 pertaining to the waste tank vapor characterization project. Information covers the following topics: project management; organic sampling and analysis; inorganic sampling and analysis; waste tank vapor data reports; and the waste tanks vapor database

Project control of WENDELSTEIN 7-X

International Nuclear Information System (INIS)

Buende, R.; Gottschewsky, M.; Heinrich, S.

2001-01-01

WENDELSTEIN 7-X (W7-X) is an experimental stellarator presently under construction at the new branch of IPP Garching at Greifswald. Since its beginning in 1996, the project W7-X Construction has been incorporating a comprehensive project control activity to assure the plant is constructed according to schedule and budget. The working fields of the project control--organization, planning and controlling--are described together with the relevant boundary conditions of the project. The activities in these fields are highlighted and an overview of the status of the project is given with emphasis on the components on the time-critical path. As conclusions some important issues for the future of the project are specified

Cassandra - D7.3.4 - M24 status report dissemination results

NARCIS (Netherlands)

Klievink, A.J.

2013-01-01

This deliverable is a status report on the dissemination activities and results in the CASSANDRA project. These status reports are made regularly, with two more to come. Together, these make up deliverable D7.3 – Dissemination results. In this fifth report, the results of the dissemination

Dietary intake and nutritional status of children and adolescents in Europe

NARCIS (Netherlands)

Lambert, J.; Agostoni, C.; Elmadfa, I.; Hulshof, K.; Krause, E.; Livingstone, B.; Socha, P.; Pannemans, D.; Samartín, S.

2004-01-01

The objective of this project was to collect and evaluate data on nutrient intake and status across Europe and to ascertain whether any trends could be identified. Surveys of dietary intake and status were collected from across Europe by literature search and personal contact with country experts.

Status of the Next European Dipole (NED) Activity of the Collaborated Accelerator Research in Europe (CARE) Project

CERN Document Server

Devred, Arnaud; Baynham, D Elwyn; Boutboul, T; Canfer, S; Chorowski, M; den Ouden, A; Fabbricatore, P; Farinon, S; Fessia, P; Fydrych, J; Félice, H; Greco, Michela; Greenhalgh, J; Leroy, D; Loveridge, P W; Michel, F; Oberli, L R; Pedrini, D; Polinski, J; Previtali, V; Quettier, L; Rifflet, J M; Rochford, J; Rondeaux, F; Sanz, S; Sgobba, Stefano; Sorbi, M; Toral-Fernandez, F; Van Weelderen, R; Vincent-Viry, O; Volpini, G; Védrine, P

2005-01-01

Plans for LHC upgrade and for the final focalization of linear colliders call for large aperture and/or high-performance dipole and quadrupole magnets that may be beyond the reach of conventional NbTi magnet technology. The Next European Dipole (NED) activity was launched on January 1st, 2004 to promote the development of high-performance, Nb$_{3}$Sn wires in collaboration with European industry (aiming at a non-copper critical current density of 1500 A/mm2 at 4.2 K and 15 T) and to assess the suitability of Nb$_{3}$Sn technology to the next generation of accelerator magnets (aiming at an aperture of 88 mm and a conductor peak field of 15 T). It is integrated within the Collaborated Accelerator Research in Europe (CARE) project, involves seven collaborators, and is partly funded by the European Union. We present here an overview of the NED activity and we report on the status of the various work packages it encompasses.

Status report on the NESC1 project

Energy Technology Data Exchange (ETDEWEB)

Hurst, R C; McGarry, D [European Commission Joint Research Centre Petten (Netherlands); Wintle, J [AEA Technology, Risley (United Kingdom); Hemsworth, B [HSE Nuclear Installations Inspectorate Bootle, Merseyside (United Kingdom)

1997-09-01

The Spinning Cylinder Project is the first joint international collaboration of the Network for Evaluating Steel Components (NESC) and is based around a large scale spinning cylinder test. This paper summarizes how the test conditions were defined and analysed, and how a method for detecting the moment of crack growth was developed. Now that the test has been successfully completed, the complex evaluation procedures can be commenced. The results of the test will constitute an important international benchmark for the understanding and validation of fracture methodologies used by the nuclear industry to assess reactor pressure vessels against pressurized thermal shock. (author). 13 refs, 3 figs.

Status of the Multipurpose Canister (MPC) Project

International Nuclear Information System (INIS)

Hopper, J.P.

1996-01-01

The multipurpose canister (MPC) project represents a cornerstone of the current U.S. Department of Energy's Office of Civilian Radioactive Waste Management (OCRWM) program for handling spent nuclear fuel. The MPC and associated support equipment is being designed to accommodate the requirements for not only storage and transport but also for the specified disposal requirements of the mined geologic repository system. The phase 1 design effort for the MPC system, being performed by the Westinghouse team on behalf of TRW Environmental Safety Systems (TESS), the OCRWM management ampersand operating (M ampersand O) contractor, is on schedule for delivery of completed safety analysis reports (SARs) in April 1996

Current status and future direction of INPRO (International Project on Innovative Nuclear Reactors and Fuel Cycles)

International Nuclear Information System (INIS)

Omoto, Akira; Moriwaki, Masanao; Sugimoto, Jun; Nakai, Ryodai

2007-01-01

INPRO is an international forum to consider jointly the international and national actions required to achieve desired innovations in nuclear reactors and fuel cycles so as to ensure that nuclear energy is available to contribute to a sustainable development of the human, and IAEA becomes the secretariat for INPRO. The number of the members counts 28 by recent participation of Japan and U.S.A. now, and it is a unique forum to bring together both technology users and technology holders, that includes 5 countries which do not still have nuclear power generation. Until now it was phase I, and focused its activities to make clear the desired characteristics of nuclear energy system toward the future, and to develop methodology to evaluate various nuclear energy systems, but it shifted to phase II from July, 2006, and it planned three areas of activities such as improvement of evaluation methodology, institutional/infrastructure oriented activities and a collaborative project of technology development. Current status and future direction of INPRO was presented to encourage Japan in significant contributions of these three areas. (T. Tanaka)

Controlled ecological life support system breadboard project, 1988

Science.gov (United States)

Knott, W. M.

1990-01-01

The Closed Ecological Life Support System (CELSS) Breadboard Project, NASA's effort to develop the technology required to produce a functioning bioregenerative system, is discussed. The different phases of the project and its current status are described. The relationship between the project components are shown, and major project activities for fiscal years 1989 to 1993 are listed. The Biomass Production Chamber (BPC) became operational and tests of wheat as a single crop are nearing completion.

Status of spallation neutron source

Energy Technology Data Exchange (ETDEWEB)

Oyama, Yukio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

1997-03-01

Existing and planned facilities using proton accelerator driven spallation neutron source are reviewed. These include new project of neutron science proposed from Japan Atomic Energy Research Institute. The present status of facility requirement and accelerator technology leads us to new era of neutron science such as neutron scattering research and nuclear transmutation study using very intense neutron source. (author)

Current status and future prospects of Japanese national project on coated conductor development and its applications

Science.gov (United States)

Shiohara, Y.; Yoshizumi, M.; Izumi, T.; Yamada, Y.

2008-09-01

Four years of the current five-year national project since 2003 for development of coated conductors using Y-system superconductors have passed and lots of remarkable results have been achieved. In this paper, the current status and the future prospect of this project are reviewed. The current national project comprises several groups of national laboratories, universities and private companies. The group of high performance tape development, consisting of Fujikura and SRL-NCCC, has worked on the tape by PLD-REBCO superconducting tapes on the PLD-CeO 2/IBAD-GZO buffered substrates. The high product of Ic and L equal to 112,166 A m was achieved in the 368 m-304.8 A GdBCO tape whose Ic value is mostly above 350 A/cm-w. The performance under the magnetic fields was also improved up to 42 A at 3 T in a GdBCO short film with doping of ZrO 2. About 61 m long GdBCO tape with ZrO 2 doping showed a high Ic value of 220 A at self field and 30 A at 3 T. On the other hand, the other group focusing on the low production cost has worked on processes of TFA-MOD and MOCVD, etc. The extremely high Ic value of 735 A/cm-w was attained in the TFA-MOD films on PLD-CeO 2/IBAD-GZO/Hastelloy C276 substrate by means of using the effect of Ba-poor nominal composition. In the efforts for long tape production, 200 m long tapes with high Ic values of 200 A/cm-w and 205 A/cm-w were obtained by MOD-YBCO/PLD-CeO 2/IBAD-GZO/Hastelloy C276 and PLD-HoBCO on buffered NiW substrate, respectively. The Ic × L value of the MOD-derived tape was 40,000 A m, which is the highest value in the world by the MOD process. Based on the above achievements on the coated conductor process development, two new additional goals were set in the project. One is the development for the extremely low cost tape and another is the development of the basic technologies for making the electric power devices including cables, transformers, motors, current-limiters and cryocoolers. Some of the new themes already revealed the

Current status and future prospects of Japanese national project on coated conductor development and its applications

International Nuclear Information System (INIS)

Shiohara, Y.; Yoshizumi, M.; Izumi, T.; Yamada, Y.

2008-01-01

Four years of the current five-year national project since 2003 for development of coated conductors using Y-system superconductors have passed and lots of remarkable results have been achieved. In this paper, the current status and the future prospect of this project are reviewed. The current national project comprises several groups of national laboratories, universities and private companies. The group of high performance tape development, consisting of Fujikura and SRL-NCCC, has worked on the tape by PLD-REBCO superconducting tapes on the PLD-CeO 2 /IBAD-GZO buffered substrates. The high product of I c and L equal to 112,166 A m was achieved in the 368 m-304.8 A GdBCO tape whose I c value is mostly above 350 A/cm-w. The performance under the magnetic fields was also improved up to 42 A at 3 T in a GdBCO short film with doping of ZrO 2 . About 61 m long GdBCO tape with ZrO 2 doping showed a high I c value of 220 A at self field and 30 A at 3 T. On the other hand, the other group focusing on the low production cost has worked on processes of TFA-MOD and MOCVD, etc. The extremely high I c value of 735 A/cm-w was attained in the TFA-MOD films on PLD-CeO 2 /IBAD-GZO/Hastelloy C276 substrate by means of using the effect of Ba-poor nominal composition. In the efforts for long tape production, 200 m long tapes with high I c values of 200 A/cm-w and 205 A/cm-w were obtained by MOD-YBCO/PLD-CeO 2 /IBAD-GZO/Hastelloy C276 and PLD-HoBCO on buffered NiW substrate, respectively. The I c x L value of the MOD-derived tape was 40,000 A m, which is the highest value in the world by the MOD process. Based on the above achievements on the coated conductor process development, two new additional goals were set in the project. One is the development for the extremely low cost tape and another is the development of the basic technologies for making the electric power devices including cables, transformers, motors, current-limiters and cryocoolers. Some of the new themes already

A proteomic method for analysis of CYP450s protein expression changes in carbon tetrachloride induced male rat liver microsomes

International Nuclear Information System (INIS)

Jia Nuan; Liu Xin; Wen Jun; Qian Linyi; Qian Xiaohong; Wu Yutian; Fan Guorong

2007-01-01

Carbon tetrachloride (CCl 4 ) is a well-known model compound for producing chemical hepatic injury. Cytochrome P450 is an important monooxygenase in biology. We investigated the CYP450 protein expression in the in vivo hepatotoxicity of rats induced by CCl 4 . In this experiment, CCl 4 were administered to male rats, and their livers at 24 h post-dosing were applied to the proteomic analysis. Blood biochemistry and histopathology were examined to identify specific changes. At the same time, a novel acetylation stable isotopic labeling method coupled with LTQ-FTICR mass spectrometry was applied to disclose the changes of cytochrome P450 expression amounts. The quantitative proteomics method demonstrated its correlation coefficient was 0.9998 in a 100-fold dynamic range and the average ratio of the labeled peptides was 1.04, which was very close to the theoretical ratio of 1.00 and the standard deviation (S.D.) of 0.21. With this approach, 17 cytochrome P450 proteins were identified and quantified with high confidence. Among them, the expression amount of 2C11, 3A2, and 2 E1 were down-regulated, while that of 2C6, 2B2, and 2B1 were up-regulated

Status and further plans for the Halden project MMS activities

International Nuclear Information System (INIS)

Oewre, Fridtjov

2004-01-01

The Halden Reactor Project is a joint undertaking of nuclear organizations in 19 countries sponsoring a jointly financed research programme under the auspices of the OECD NEA. The programme is renewed every third year. The three main research areas at the Halden Project are: Fuels-, Materials- and Man-Machine Systems (MMS) research. The MMS research addresses issues related to human-machine interaction in computerized control rooms as well as the development and test of new technology related to safe and reliable operation of nuclear power plants. The MMS research at the Halden Project is closely tied with experimental work in two laboratories constituting what is now called the MTO-labs (MTO=Man-Technology-Organization). The new MTO-lab building was opened in the spring 2004. One of the laboratories is the nuclear simulator-based Halden Man-Machine Laboratory (HAMMLAB). The other laboratory is called the Halden Virtual Reality Centre (HVRC). The paper first introduces the new MTO-lab and outlines Halden's capabilities of perform MMS research. Furthermore the paper discusses three selected topics addressed within the current Halden MMS programme focusing on our approach to obtain data for human reliability assessment, the work on design and evaluation of innovative human system interfaces and our work on integrated wearable computing technologies for field operators. A short overview of our plans for future research as part of the international Halden Reactor Project concludes the paper. (author)

Hepatoprotective effect of Forsythiae Fructus water extract against carbon tetrachloride-induced liver fibrosis in mice.

Science.gov (United States)

Zhang, Yi; Miao, Hui; Yan, Hongyu; Sheng, Yuchen; Ji, Lili

2018-05-23

The fruit of Forsythia suspensa (Thunb.) Vahl, named Forsythiae Fructus (Lian-Qiao), is a well-known traditional Chinese medicine (TCM) used for clearing away heat and toxic material, eliminating the mass and relieving swelling. This study aims to observe the attenuation of the water extract of Forsythiae Fructus (FSE) on carbon tetrachloride (CCl 4 )-induced hepatic fibrosis in male C57BL/6 mice. Hepatic fibrosis was induced in male C57BL/6 mice by intraperitoneal injection with 2 ml/kg CCl 4 (mixed 1: 3 in olive oil) twice a week for 4 weeks. At the same time, the mice were orally given with FSE (1, 2 g/kg) every day for 4 weeks. Serum biochemical parameters, gene and protein expression related to liver fibrosis were analyzed. The contents of forsythiaside A and forsythin in FSE were measured by high-performance liquid chromatography (HPLC). Results of serum alanine/aspartate aminotransferase (ALT/AST) activity and liver histological evaluation both showed the protection of FSE against CCl 4 -induced liver injury. Further, the anti-fibrotic effects of FSE was evidenced by the results of Masson's trichrome and Sirius red staining, liver hydroxyproline content, and serum amounts of hyaluronic acid, laminin, collagen Ⅳ and type III procollagen (PCIII). FSE also reduced the expression of α-smooth muscle actin (α-SMA) in livers from CCl 4 -injured mice. Additionally, FSE decreased the increased hepatic expression of fibroblast-specific protein 1 (FSP1) and vimentin induced by CCl 4 in mice. FSE attenuates CCl 4 -induced liver fibrosis in mice by inhibiting hepatic stellate cells (HSCs) activation, reducing hepatic extracellular matrix (ECM) disposition and reversing epithelial-mesenchymal transition (EMT). Copyright © 2018 Elsevier B.V. All rights reserved.

Solanum muricatum Aiton Juice as A Hepatoprotective Agent in Wistar Rats Induced With Carbon Tetrachloride

Directory of Open Access Journals (Sweden)

Justine Sim Wei Yang

2015-12-01

Full Text Available Background: Liver participates in various metabolic processes in human body. Exposures to toxins such as carbon tetrachloride (CCl4 results in hepatocyte destruction and release the cell contents. Enzymes such as serum glutamic pyruvic transaminase (SGPT were used as a parameter to diagnose liver damage. Pepino (Solanum muricatum Aiton contains antioxidants that protect liver from hepatoxicity. The aim of this experiment is to determine the effect of pepino in protecting the hepatocyte from hepatotoxic effect of CCl4. Methods: A total of 16 Wistar rats used as the subject were divided into Control and Therapeutic Group. The Control group was induced with CCl4 but was not given pepino juice. Meanwhile, the Therapeutic Group was given pepino juice for 10 days. For induction of hepatotoxicity, CCl4 10% was given at a dosage of 2.0 ml/kg intra-peritoneal. Each Wistar rat in Therapeutic Group was given 1.0 ml of 300 g/ml pepino juice via oral feeding. Spectrophotometer with adjusted wavelength of 340 nm was used to measure SGPT level of the Wistar rats and statistical T-test was used to analyze the data. Results: Wistar rats in Therapeutic group showed a larger decrease (6898.9 IU/L–79.1 IU/L in SGPT level compared to the Control group (6469.8 IU/L–418.5 IU/L. The SGPT level of the Wistar rat in Therapeutic group reached normal baseline (50 IU/L–150 IU/L. The significance of the experiment was supported by the T-test, P-value <0.05 Discussion: Pepino juice had antioxidants that protect the hepatocyte of Wistar rats from free radicals. The synergistic action of antioxidants and hepatocyte regeneration of Wistar rats in Therapeutic group caused a decrease in SGPT level. Therefore, the experiment concluded that pepino juice at the dosage of 300 g/ml has hepatoprotective effect.

Status of Pantex Plant Waste Management Project/program control system

International Nuclear Information System (INIS)

Price, Wesley J.; Matthews, William L.

1992-01-01

During a December 1990 Waste Management Program Review held in Albuquerque, New Mexico, the Waste Management and Operational Surety Division (WMOSD) introduced the project control system to be used for the Waste Management (WM) Operations Program. The system was entitled 'TRAC-WM' (Tracking and Control for Waste Management). The stated objective for this system was to establish a frame work for planning, managing, and controlling work within the WM program. As a result Mason and Hanger (the operating contractor at the Pantex Plant) initiated the development of a computerized waste management project tracking system. (author)

Total and Spectral Solar Irradiance Sensor (TSIS) Project Status

Science.gov (United States)

Carlisle, Candace

2018-01-01

TSIS-1 studies the Sun's energy input to Earth and how solar variability affects climate. TSIS-1 will measure both the total amount of light that falls on Earth, known as the total solar irradiance (TSI), and how that light is distributed among ultraviolet, visible and infrared wavelengths, called solar spectral irradiance (SSI). TSIS-1 will provide the most accurate measurements of sunlight and continue the long-term climate data record. TSIS-1 includes two instruments: the Total Irradiance Monitor (TIM) and the Spectral Irradiance Monitor (SIM), integrated into a single payload on the International Space Station (ISS). The TSIS-1 TIM and SIM instruments are upgraded versions of the two instruments that are flying on the Solar Radiation and Climate Experiment (SORCE) mission launched in January 2003. NASA Goddard's TSIS project responsibilities include project management, system engineering, safety and mission assurance, and engineering oversight for TSIS-1. TSIS-1 was installed on the International Space Station in December 2017. At the end of the 90-day commissioning phase, responsibility for TSIS-1 operations transitions to the Earth Science Mission Operations (ESMO) project at Goddard for its 5-year operations. NASA contracts with the University of Colorado Laboratory for Atmospheric and Space Physics (LASP) for the design, development and testing of TSIS-1, support for ISS integration, science operations of the TSIS-1 instrument, data processing, data evaluation, calibration and delivery to the Goddard Earth Science Data and Information Services Center (GES DISC).

Next Generation Nuclear Plant Project 2009 Status Report

Energy Technology Data Exchange (ETDEWEB)

Larry Demick; Jim Kinsey; Keith Perry; Dave Petti

2010-05-01

The mission of the NGNP Project is to broaden the environmental and economic benefits of nuclear energy technology to the United States and other economies by demonstrating its applicability to market sectors not served by light water reactors (LWRs). Those markets typically use fossil fuels to fulfill their energy needs, and high temperature gas-cooled reactors (HTGRs) like the NGNP can reduce this dependence and the resulting carbon footprint.

Pilot project of atomic energy technology record

International Nuclear Information System (INIS)

Song, K. C.; Kim, Y. I.; Kim, Y. G.

2011-12-01

Project of the Atomic Energy Technology Record is the project that summarizes and records in each category as a whole summary from the background to the performance at all fields of nuclear science technology which researched and developed at KAERI. This project includes Data and Document Management System(DDMS) that will be the system to collect, organize and preserve various records occurred in each research and development process. To achieve these goals, many problems should be solved to establish technology records process, such as issues about investigation status of technology records in KAERI, understanding and collection records, set-up project system and selection target field, definition standards and range of target records. This is a research report on the arrangement of research contents and results about pilot project which records whole nuclear technology researched and developed at KAERI in each category. Section 2 summarizes the overview of this pilot project and the current status of technology records in domestic and overseas, and from Section 3 to Section 6 summarize contents and results which performed in this project. Section 3 summarizes making TOC(Table of Content) and technology records, Section 4 summarizes sectoral templates, Section 5 summarizes writing detailed plan of technology records, and Section 6 summarizes Standard Document Numbering System(SDNS). Conclusions of this report are described in Section 7

The White Rabbit project

CERN Document Server

Serrano, J; Gousiou, E; van der Bij, E; Wlostowski, T; Daniluk, G; Lipinski, M

2013-01-01

White Rabbit (WR) is a multi-laboratory, multi- company collaboration for the development of a new Ethernet-based technology which ensures sub-nanosecond synchronisation and deterministic data transfer. The project uses an open source paradigm for the development of its hardware, gateware and software components. This article provides an introduction to the technical choices and an explanation of the basic principles underlying WR. It then describes some possible applications and the current status of the project. Finally, it provides insight on current developments and future plans.

Greenhouse Gas CCI Project (GHG-CCI): Overview and current status

Science.gov (United States)

Buchwitz, M.; Burrows, J. P.; Reuter, M.; Schneising, O.; Noel, S.; Bovensmann, H.; Notholt, J.; Boesch, H.; Parker, R.; Hasekamp, O. P.; Guerlet, S.; Aben, I.; Lichtenberg, G.; Crevoisier, C. D.; Chedin, A.; Stiller, G. P.; Laeng, A.; Butz, A.; Blumenstock, T.; Orphal, J.; Sussmann, R.; De Maziere, M. M.; Dils, B.; Brunner, D.; Popp, C. T.; Buchmann, B.; Chevallier, F.; Bergamaschi, P. M.; Frankenberg, C.; Zehner, C.

2011-12-01

The GHG-CCI project is one of several projects of ESA's Climate Change Initiative (CCI), which will deliver various Essential Climate Variables (ECVs). The goal of GHG-CCI is to deliver global satellite-derived data sets of the two most important anthropogenic greenhouse gases (GHGs) carbon dioxide (CO2) and methane (CH4) suitable to obtain information on regional CO2 and CH4 surface sources and sinks as needed for better climate prediction. The GHG-CCI core ECV data products are column-averaged mole fractions of CO2 and CH4, i.e., XCO2 and XCH4, retrieved from SCIAMACHY on ENVISAT and TANSO on GOSAT. Other satellite instruments will be used to provide constraints in upper layers such as IASI, MIPAS, and ACE-FTS. Which of the advanced algorithms, which are under development, will be the best for a given data product still needs to be determined. For each of the 4 GHG-CCI core data products - XCO2 and XCH4 from SCIAMACHY and GOSAT - several algorithms will be further developed and the corresponding data products will be inter-compared to identify which data product is the most appropriate. This includes comparisons with corresponding data products generated elsewhere, most notably with the operational data products of GOSAT generated at NIES and the NASA/ACOS GOSAT XCO2 product. This activity, the so-called "Round Robin exercise", will be performed in the first two years of this project. At the end of the 2 year Round Robin phase a decision will be made which of the algorithms performs best. The selected algorithms will be used to generate the first version of the ECV GHG. In the last six months of this 3 year project the resulting data products will be validated and made available to all interested users. In the presentation and overview about this project will be given. Focus will be on a discussion and intercomparison of the various data products focusing on CO2.

Reactors Project Delivery: The Value of Experiance

International Nuclear Information System (INIS)

Stosic, V. Zoran

2014-01-01

State of Affairs: Energy Potential and Density versus Environmental Load of different Energy Sources, Development of Fuel into Energy/Electricity Generation, Production Costs of Electricity, Contributions of Nuclear Energy to Security of Energy Supply, Recent Nuclear Development, Public Support growing again. Projects Status: Reactors under Construction, Different Projects Industrial Schemes, Projects Overview. The Value of Experience: Licensing, Standardization on Early Engineering Activities, Supply Chain and Manufacturing of Heavy Components, Installation, Procurement. (author)

Salt Repository Project. FY-84 technical project plan

International Nuclear Information System (INIS)

1984-08-01

The FY 84 technical plans for the Salt Repository Project (SRP) are briefly presented. The objectives of the project in relation to the Civilian Radioactive Waste Management (CRWM) program are discused and the technical activities directed toward accomplishing these objectives are detailed. A budget is presented for each of the Level 2 Work Breakdown Structure Tasks (Systems, Waste Package, Site, Repository, Regulatory and Institutional, Test Facilities, Exploratory Shaft, Land Acquisition, and Program Management) in an appendix. An overall description, current status, and planned activities are presented for each of the subtasks which make up the above-mentioned Level 2 tasks. Milestones and their definitions for the plan year, as well as milestones for the outyears are also presented at this same subtask level for each subtask

Nursing Manpower Licensed in Kentucky, 1979-1981. Kentucky Nursing Education Project.

Science.gov (United States)

Kentucky State Council on Higher Education, Frankfort.

Data on nurses licensed in Kentucky for 1979-1981 are presented, as part of the Kentucky Nursing Education Project. Information is provided on: licensure status, home state/district/county, employment status, employment state/district/county, field of employment in nursing, position, highest educational level attained, age, sex, marital status,…

Status of the object-oriented EGS interface project

International Nuclear Information System (INIS)

Yacout, A.M.; Dunn, W.L.; Nelson, W.R.; Lui, P.; Bielajew, A.F.; Hirayama, H.; Namito, Y.

2000-01-01

The object-oriented EGS interface project seeks to simplify - using modern object-oriented and visual user interface techniques - the geometry and scoring aspects of the process of running the EGS code. The project will create an extremely user-friendly EGS package that retains and exploits the well documented physics advantages of EGS but removes the requirement that the user write HOWFAR and AUSGAB subroutines to define the geometry and scoring aspects of each new problem. In addition, several physics enhancements will be incorporated in EGS5. Although EGS5 will be able to be used in the traditional way - in a stand-alone fashion with users writing their own geometry and scoring subroutines - it is designed to be used in a completely new way - linked to a user interface through which users can manage all aspects of problem specification and code operation. This paper concentrates on the object-oriented user interface, which will dramatically simplify defining problem-specific detail for EGS. The 'EGS5 + VUI1' package will allow users to solve independent problems by run-time linking of the EGS5 code with class libraries that encapsulate the geometry and scoring aspects of each problem. Some simple example problems are considered in order to illustrate features of the EGS5 + VUI1 package. (author)

Status of Kijang Resarch Reactor Project

Energy Technology Data Exchange (ETDEWEB)

Kim, Jee. Y; Kwon, T. H.; Kim, Jun. Y.; Oh, G. B. [KAERI, Daejeon (Korea, Republic of)

2016-05-15

The High-flux Advanced Neutron Application Reactor (HANARO) is a multi-purpose reactor in Korea Atomic Energy Research Institute (KAERI) and is being utilized for neutron scattering experiments, material and fuel tests for nuclear power plants, radio-isotope (RI) productions, silicon doping, neutron activation analysis, and neutron radiography. In medical applications, the majority of RIs produced using HANARO are I-131 and Ir-192. Other RIs such as Mo-99 are coming from imports. The self-sufficiency of RI demand becomes an important issue for the public health service in Korea. In this regard the Kijang Research Reactor (KJRR) project was officially launched on the first of April 2012 in need to provide the self-sufficiency of RI demand including Mo-99, increase the neutron transportation doping (NTD) capacity and develop technologies related to the research reactor. When CP is granted, the first excavation is planned to start at the end of this year. In next year, pouring the first concrete and energizing 154kV will follow. In 2018, it is planned to complete utility building construction and reactor building construction.

Cassandra - D7.3.5 - M30 status : Report dissemination results

NARCIS (Netherlands)

Klievink, A.J.

2014-01-01

This deliverable is a status report on the dissemination activities and results in the CASSANDRA project. These status reports are made regularly, with one more to come at the project’s finish. Together, these make up deliverable D7.3 – Dissemination results. In this report, the results of the

The OPTHER Project: Progress toward the THz Amplifier

DEFF Research Database (Denmark)

Paoloni, C; Brunetti, F; Di Carlo, A

2011-01-01

This paper describes the status of the OPTHER (OPtically driven TeraHertz AmplifiERs) project and progress toward the THz amplifier realization. This project represents a considerable advancement in the field of high frequency amplification. The design and realization of a THz amplifier within...... this project is a consolidation of efforts at the international level from the leading scientific and industrial European organizations working with vacuum electronics....

Concentrating Solar Power Projects - KaXu Solar One | Concentrating Solar

Science.gov (United States)

Power | NREL KaXu Solar One This page provides information on KaXu Solar One, a concentrating solar power (CSP) project, with data organized by background, parcipants and power plant configuration . Status Date: April 14, 2015 Project Overview Project Name: KaXu Solar One Country: South Africa Location

Recovery of metal chlorides from their complexes by molten salt displacement

International Nuclear Information System (INIS)

McLaughlin, D.F.; Stoltz, R.A.

1989-01-01

This patent describes a process for recovering zirconium or hafnium chloride from a complex of zirconium or hafnium tetrachloride and phosphorus oxychloride. The process comprising: introducing liquid complex of zirconium or hafnium tetrachloride and phosphorus oxychloride into an upper portion of a feed column containing zirconium or hafnium tetrachloride vapor and phosphorus oxychloride vapor. The liquid complex absorbing zirconium or hafnium tetrachloride vapor and producing a bottoms liquid and also producing a phosphorus oxychloride vapor stripped of zirconium or hafnium tetrachloride; introducing the bottoms liquid into a molten salt containing displacement reactor, the reactor containing molten salt comprising at least 30 mole percent lithium chloride and at least 30 mole percent of at least one other alkali metal chloride, the reactor being heated to 30-450 0 C to displace phosphorus oxychloride from the complex and product zirconium or hafnium tetrachloride vapor and phosphorus oxychloride vapor and zirconium or hafnium tetrachloride-containing molten salt; introducing the zirconium or hafnium tetrachloride vapor and the phosphorus oxychloride vapor into the feed column below the point of introduction of the liquid stream; introducing the zirconium or hafnium tetrachloride containing-molten salt into a recovery vessel where zirconium or hafnium tetrachloride is removed from the molten salt to produce zirconium or hafnium tetrachloride product and zirconium or hafnium chloride-depleted molten salt; and recycling the zirconium or hafnium tetachloride-depleted molten salt to the displacement reactor

Current status of the KNPP units 1 to 4 decommissioning projects

International Nuclear Information System (INIS)

Benbow, R.

2010-01-01

The PMU has been established in support of the KNPP Decommissioning Division. All of the Infrastructure Projects associated with Decommissioning have been identified. All the major projects are either in Contract or have the Tender Packages prepared and are being managed/implemented through the EBRD Procurement Process. KNPP Decommissioning is being supported with the necessary documentation, tools and equipment

Continued emissions of carbon tetrachloride from the United States nearly two decades after its phaseout for dispersive uses

Science.gov (United States)

Hu, Lei; Montzka, Stephen A.; Miller, Ben R.; Andrews, Arlyn E.; Miller, John B.; Lehman, Scott J.; Sweeney, Colm; Miller, Scot M.; Thoning, Kirk; Siso, Carolina; Atlas, Elliot L.; Blake, Donald R.; de Gouw, Joost; Gilman, Jessica B.; Dutton, Geoff; Elkins, James W.; Hall, Bradley; Chen, Huilin; Fischer, Marc L.; Mountain, Marikate E.; Nehrkorn, Thomas; Biraud, Sebastien C.; Moore, Fred L.; Tans, Pieter

2016-03-01

National-scale emissions of carbon tetrachloride (CCl4) are derived based on inverse modeling of atmospheric observations at multiple sites across the United States from the National Oceanic and Atmospheric Administration's flask air sampling network. We estimate an annual average US emission of 4.0 (2.0-6.5) Gg CCl4 y-1 during 2008-2012, which is almost two orders of magnitude larger than reported to the US Environmental Protection Agency (EPA) Toxics Release Inventory (TRI) (mean of 0.06 Gg y-1) but only 8% (3-22%) of global CCl4 emissions during these years. Emissive regions identified by the observations and consistently shown in all inversion results include the Gulf Coast states, the San Francisco Bay Area in California, and the Denver area in Colorado. Both the observation-derived emissions and the US EPA TRI identified Texas and Louisiana as the largest contributors, accounting for one- to two-thirds of the US national total CCl4 emission during 2008-2012. These results are qualitatively consistent with multiple aircraft and ship surveys conducted in earlier years, which suggested significant enhancements in atmospheric mole fractions measured near Houston and surrounding areas. Furthermore, the emission distribution derived for CCl4 throughout the United States is more consistent with the distribution of industrial activities included in the TRI than with the distribution of other potential CCl4 sources such as uncapped landfills or activities related to population density (e.g., use of chlorine-containing bleach).

Rat liver mitochondrial damage under acute or chronic carbon tetrachloride-induced intoxication: Protection by melatonin and cranberry flavonoids

International Nuclear Information System (INIS)

Cheshchevik, V.T.; Lapshina, E.A.; Dremza, I.K.; Zabrodskaya, S.V.; Reiter, R.J.; Prokopchik, N.I.; Zavodnik, I.B.

2012-01-01

In current societies, the risk of toxic liver damage has markedly increased. The aim of the present work was to carry out further research into the mechanism(s) of liver mitochondrial damage induced by acute (0.8 g/kg body weight, single injection) or chronic (1.6 g/ kg body weight, 30 days, biweekly injections) carbon tetrachloride – induced intoxication and to evaluate the hepatoprotective potential of the antioxidant, melatonin, as well as succinate and cranberry flavonoids in rats. Acute intoxication resulted in considerable impairment of mitochondrial respiratory parameters in the liver. The activity of mitochondrial succinate dehydrogenase (complex II) decreased (by 25%, p 4 displayed obvious irreversible impairments. Long-term melatonin administration (10 mg/kg, 30 days, daily) to chronically intoxicated rats diminished the toxic effects of CCl 4 , reducing elevated plasma activities of alanine aminotransferase and aspartate aminotransferase and bilirubin concentration, prevented accumulation of membrane lipid peroxidation products in rat liver and resulted in apparent preservation of the mitochondrial ultrastructure. The treatment of the animals by the complex of melatonin (10 mg/kg) plus succinate (50 mg/kg) plus cranberry flavonoids (7 mg/kg) was even more effective in prevention of toxic liver injury and liver mitochondria damage. Highlights: ► After 30-day chronic CCl 4 intoxication mitochondria displayed considerable changes. ► The functional parameters of mitochondria were similar to the control values. ► Melatonin + succinate + flavonoids prevented mitochondrial ultrastructure damage. ► The above complex enhanced regenerative processes in the liver.

Carbon tetrachloride contamination, 200 West Area, Hanford Site: Arid Site Integrated Demonstration for remediation of volatile organic compounds

International Nuclear Information System (INIS)

Last, G.V.; Rohay, V.J.

1991-01-01

The Arid State Integrated Demonstration is a US Department of Energy (DOE) program targeted at the acquisition, development, demonstration, and deployment of technologies for evaluation and cleanup of volatile organic and associated contaminants in soils and ground waters. Several DOE laboratories, universities, and industry will participate in the program. Candidate technologies will be demonstrated in the areas of site characterization; performance prediction, monitoring, and evaluations; contaminant extraction and ex situ treatment; in situ remediations; and site closure and monitoring. The performance of these demonstrated technologies will be compared to baseline technologies and documented to promote the transfer of new technologies to industry for use at DOE facilities. The initial host site is the Hanford Site's 200 West Area. The location of the demonstration contains primarily carbon tetrachloride (CCl 4 ), chloroform, and a variety of associated mixed waste contaminants. Chemical processes used to recover and purify plutonium at Hanford's plutonium finishing plant (Z Plant) resulted in the production of actinide-bearing waste liquid. Both aqueous and organic liquid wastes were generated, and were routinely discharged to subsurface disposal facilities. The primary radionuclide in the waste streams was plutonium, and the primary organic was CCl 4 . This paper contains brief descriptions of the principal CCl 4 waste disposal facilities in Hanford's 200 West Area, associated hydrogeology, existing information on the extent of soil and ground-water contamination, and a conceptual outline of suspected subsurface CCl 4 distributions

The HGF strategy project

International Nuclear Information System (INIS)

Knebel, J.U.; Fellmoser, F.; Lefhalm, C.; Mack, K.; Pettan, C.; Piecha, H.; Konys, J.; Adelhelm, C.; Glasbrenner, H.; Muscher, H.; Novotny, J.; Voss, Z.; Wedemeyer, O.; Mueller, G.; Heinzel, A.; Schumacher, G.; Huber, R.; Zimmermann, F.; Groetzbach, G.; Dorr, B.; Carteciano, L.N.

2000-01-01

Within the Hermann von Helmholtz-Gemeinschaft Deutscher Forschungszentren (HGF) an HGF-Strategy Fund Project entitled 'Innovative Technologies to Reduce Radiotoxicity' is funded since October 1999. The objectives of this HGF-Strategy Fund Project is the development of new methods and technologies to design and manufacture thin-walled and highly thermally-loaded surfaces which are cooled by a corrosive heavy liquid metal (lead-bismuth eutectic). The result of this project will be the basic scientific-technical tool which allows the conception and the design of a European Demonstrator of an ADS system (cf. 32.23.05). The work performed at Forschungszentrum Karlsruhe is embedded in a broad European research and development programme on ADS systems. The project is divided in three sub-projects: Sub-Project 1: Thermalhydraulic Investigations, Sub-Project 2: Material Specific Investigations, Sub-Project 3: Oxygen Control System. This progress report gives a general description of the project and its envisaged objectives. As a selection of the results achieved, first, FLUTAN calculations for the COULI beam window design and, second, the oxygen control system for the KArlsruhe Lead LAboratory KALLA are described in detail. Finally, the design and status of KALLA is given. (orig.)

2016 Bioenergy Industry Status Report

Energy Technology Data Exchange (ETDEWEB)

Moriarty, Kristen L. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Milbrandt, Anelia R. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Warner, Ethan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Lewis, John E. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Schwab, Amy A. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

2018-03-03

This report provides a snapshot of the bioenergy industry status at the end of 2016. The report compliments other annual market reports from the U.S. Department of Energy’s (DOE’s) Office of Energy Efficiency and Renewable Energy offices and is supported by DOE’s Bioenergy Technologies Office (BETO). The 2016 Bioenergy Industry Status Report focuses on past year data covering multiple dimensions of the bioenergy industry and does not attempt to make future market projections. The report provides a balanced and unbiased assessment of the industry and associated markets. It is openly available to the public and is intended to compliment International Energy Agency and industry reports with a focus on DOE stakeholder needs.

Theoretical predictions of properties and volatility of chlorides and oxychlorides of group-4 elements. II. Adsorption of tetrachlorides and oxydichlorides of Zr, Hf, and Rf on neutral and modified surfaces

International Nuclear Information System (INIS)

Pershina, V.; Borschevsky, A.; Iliaš, M.; Türler, A.

2014-01-01

With the aim to interpret results of gas-phase chromatography experiments on volatility of group-4 tetrachlorides and oxychlorides including those of Rf, adsorption enthalpies of these species on neutral, and modified quartz surfaces were estimated on the basis of relativistic, two-component Density Functional Theory calculations of MCl 4 , MOCl 2 , MCl 6 − , and MOCl 4 2 with the use of adsorption models. Several mechanisms of adsorption were considered. In the case of physisorption of MCl 4 , the trend in the adsorption energy in the group should be Zr > Hf > Rf, so that the volatility should change in the opposite direction. The latter trend complies with the one in the sublimation enthalpies, ΔH sub , of the Zr and Hf tetrachlorides, i.e., Zr < Hf. On the basis of a correlation between these quantities, ΔH sub (RfCl 4 ) was predicted as 104.2 kJ/mol. The energy of physisorption of MOCl 2 on quartz should increase in the group, Zr < Hf < Rf, as defined by increasing dipole moments of these molecules along the series. In the case of adsorption of MCl 4 on quartz by chemical forces, formation of the MOCl 2 or MOCl 4 2− complexes on the surface can take place, so that the sequence in the adsorption energy should be Zr > Hf > Rf, as defined by the complex formation energies. In the case of adsorption of MCl 4 on a chlorinated quartz surface, formation of the MCl 6 2− surface complexes can occur, so that the trend in the adsorption strength should be Zr ≤ Hf < Rf. All the predicted sequences, showing a smooth change of the adsorption energy in the group, are in disagreement with the reversed trend Zr ≈ Rf < Hf, observed in the “one-atom-at-a-time” gas-phase chromatography experiments. Thus, currently no theoretical explanation can be found for the experimental observations

Theoretical predictions of properties and volatility of chlorides and oxychlorides of group-4 elements. II. Adsorption of tetrachlorides and oxydichlorides of Zr, Hf, and Rf on neutral and modified surfaces

Energy Technology Data Exchange (ETDEWEB)

Pershina, V., E-mail: V.Pershina@gsi.de [GSI Helmholtzzentrum für Schwerionenforschung, Planckstr. 1, Darmstadt D-64291 (Germany); Borschevsky, A. [Helmholtz Institute Mainz, Mainz D-55128, Germany and Centre for Theoretical Chemistry and Physics, New Zealand Institute for Advanced Study, Massey University, Private Bag 102904, 0745 North Shore MSC, Auckland (New Zealand); Iliaš, M. [Department of Chemistry, Faculty of Natural Sciences, Matej Bel University, Tajovského 40, SK-974 00 Banská Bystrica (Slovakia); Türler, A. [Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland and Laboratory for Radiochemistry and Environmental Chemistry, Paul Scherrer Institute, CH-5232 Villigen PSI (Switzerland)

2014-08-14

With the aim to interpret results of gas-phase chromatography experiments on volatility of group-4 tetrachlorides and oxychlorides including those of Rf, adsorption enthalpies of these species on neutral, and modified quartz surfaces were estimated on the basis of relativistic, two-component Density Functional Theory calculations of MCl{sub 4}, MOCl{sub 2}, MCl{sub 6}{sup −}, and MOCl{sub 4}{sup 2} with the use of adsorption models. Several mechanisms of adsorption were considered. In the case of physisorption of MCl{sub 4}, the trend in the adsorption energy in the group should be Zr > Hf > Rf, so that the volatility should change in the opposite direction. The latter trend complies with the one in the sublimation enthalpies, ΔH{sub sub}, of the Zr and Hf tetrachlorides, i.e., Zr < Hf. On the basis of a correlation between these quantities, ΔH{sub sub}(RfCl{sub 4}) was predicted as 104.2 kJ/mol. The energy of physisorption of MOCl{sub 2} on quartz should increase in the group, Zr < Hf < Rf, as defined by increasing dipole moments of these molecules along the series. In the case of adsorption of MCl{sub 4} on quartz by chemical forces, formation of the MOCl{sub 2} or MOCl{sub 4}{sup 2−} complexes on the surface can take place, so that the sequence in the adsorption energy should be Zr > Hf > Rf, as defined by the complex formation energies. In the case of adsorption of MCl{sub 4} on a chlorinated quartz surface, formation of the MCl{sub 6}{sup 2−} surface complexes can occur, so that the trend in the adsorption strength should be Zr ≤ Hf < Rf. All the predicted sequences, showing a smooth change of the adsorption energy in the group, are in disagreement with the reversed trend Zr ≈ Rf < Hf, observed in the “one-atom-at-a-time” gas-phase chromatography experiments. Thus, currently no theoretical explanation can be found for the experimental observations.

Reactivation of nuclear power plant construction projects. Plant status, policy issues and regulatory options

International Nuclear Information System (INIS)

Spangler, M.B.

1986-07-01

Prior to the TMI-2 accident on March 28, 1979, four nuclear power plant units that had previously been issued a construction permit were cancelled, principally because of reduced projections of regional power demand. Since that time, an additional 31 units with CPs have been cancelled and eight units deferred. On December 23, 1985 one of the deferred units (Limerick-2) was reactivated and construction resumed. The primary objective of this policy study is to identify the principal issues requiring office-level consideration in the event of reactivation of the construction of one or more of the nuclear power plants falling into two categories: (1) LWR units issued a construction permit whose construction has been cancelled, and (2) LWR units whose construction has been deferred. The study scope is limited to identifying regulatory issues or questions deserving analysis rather than providing, at this time, answers or recommended actions. Five tasks are addressed: a tabulation and discussion of the status of all cancelled and deferred LWR units; and identification of potential safety and environmental issues; an identification of regulatory or policy issues and needed information to determine the desirability of revising certain rules and policies; and identification of regulatory options and decision criteria; and an identification of decision considerations in determining staff requirements and organizational coordination of LWR reactivation policy and implementation efforts. 41 refs

Status of the ATLAS hadronic tile calorimeter

International Nuclear Information System (INIS)

Leitner, R.

2005-01-01

Short status of the Tile Calorimeter project is given. Major achievements in the mechanical construction of the detector modules, their instrumentation, cylinders assembly, as well as the principles of the detector front-end electronics, are described. The ideas of Tile Calorimeter module calibration are presented

Status of the NICA project at JINR

Directory of Open Access Journals (Sweden)

Kekelidze V.

2016-01-01

Full Text Available The project NICA (Nuclotron-based Ion Collider fAcility is aimed to study hot and dense baryonic matter in heavy ion collisions in the energy range up to √sNN = 11 GeV, and to study nucleon spin structure in polarized proton and deuteron collisions in the energy range up to √s = 27 GeV. The heavy ion program will be performed at the Nuclotron extracted beams with the BM@N (Baryonic Matter at Nuclotron set-up and with the MPD (MultiPurpose Detector at the NICA collider with the average luminosity of L = 1027 cm−2s−1 (for 197Au79+. The spin physics will be studied with the SPD (Spin Physics Detector at the NICA collider.

Status report on the HFR conversion and re-licensing project

International Nuclear Information System (INIS)

Wijtsma, F.G.

2003-01-01

In 1999 the HFR license holder (JRC, Petten, the Netherlands) initiated a project to study the conversion of the HFR from HEU to LEU. The first phase of this project consisted of a parametric study to determine the optimum fuel element and control rod design within given boundary conditions such as geometry, density, performance and cycle length. Results of this study are a 22 plates fuel element (550 g 235 U) at a density of 4.8 g.cm -3 and a 17 plates control rod (440 g 235 U). The second phase contains all aspects related to the conversion including a full-scale test irradiation of a prototype LEU element. The actual conversion of the HFR requires a new license. For this reason the re-licensing project has started in 2001. In this context many studies have been performed e.g. Risk Scoping Study, Safety Analyses, TOPA (Technical, Operational, Personnel and Administrative) evaluation. The license application will be based on a new Safety Report and an Environmental Impact Statement and will be submitted to the competent Authorities at the end of October 2003. (author)

The SIMPSONS project: An integrated Mars transportation system

Science.gov (United States)

Kaplan, Matthew; Carlson, Eric; Bradfute, Sherie; Allen, Kent; Duvergne, Francois; Hernandez, Bert; Le, David; Nguyen, Quan; Thornhill, Brett

In response to the Request for Proposal (RFP) for an integrated transportation system network for an advanced Martian base, Frontier Transportation Systems (FTS) presents the results of the SIMPSONS project (Systems Integration for Mars Planetary Surface Operations Networks). The following topics are included: the project background, vehicle design, future work, conclusions, management status, and cost breakdown. The project focuses solely on the surface-to-surface transportation at an advanced Martian base.

Amelioration of carbon tetrachloride-induced cirrhosis and portal hypertension in rat using adenoviral gene transfer of Akt.

Science.gov (United States)

Deng, Gang; Huang, Xiang-Jun; Luo, Hong-Wu; Huang, Fei-Zhou; Liu, Xun-Yang; Wang, Yong-Heng

2013-01-01

To investigate whether a virus constitutively expressing active Akt is useful to prevent cirrhosis induced by carbon tetrachloride (CCl4). Using cre-loxp technique, we created an Ad-myr-HA-Akt virus, in which Akt is labeled by a HA tag and its expression is driven by myr promoter. Further, through measuring enzyme levels and histological structure, we determined the efficacy of this Ad-myr-HA-Akt virus in inhibiting the development of cirrhosis induced by CCl4 in rats. Lastly, using western blotting, we examined the expression levels and/or phosphorylation status of Akt, apoptotic mediators, endothelial nitric oxide synthase (eNOS), and markers for hepatic stellate cells activation to understand the underlying mechanisms of protective role of this virus. The Ad-myr-HA-Akt virus was confirmed using polymerase chain reaction amplification of inserted Akt gene and sequencing for full length of inserted fragment, which was consistent with the sequence reported in the GenBank. The concentrations of Ad-myr-HA-Akt and adenoviral enhanced green fluorescent protein (Ad-EGFP) virus used in the current study were 5.5 × 10(11) vp/mL. The portal vein diameter, peak velocity of blood flow, portal blood flow and congestion index were significantly increased in untreated, saline and Ad-EGFP cirrhosis groups when compared to normal control after the virus was introduced to animal through tail veil injection. In contrast, these parameters in the Akt cirrhosis group were comparable to normal control group. Compared to the normal control, the liver function (Alanine aminotransferase, Aspartate aminotransferase and Albumin) was significantly impaired in the untreated, saline and Ad-EGFP cirrhosis groups. The Akt cirrhosis group showed significant improvement of liver function when compared to the untreated, saline and Ad-EGFP cirrhosis groups. The Hyp level and portal vein pressure in Akt cirrhosis groups were also significantly lower than other cirrhosis groups. The results of HE and

Reference Design Project Book: NUSEL-Homestake

OpenAIRE

Haxton, W. C.

2003-01-01

This submission includes the overview, science timeline, reference design, WBS, and mine status sections of the Homestake collaboration's Reference Design Project Book. The Project Book describes the specific plan for converting the Homestake Gold Mine into a facility for physics, earth science, and engineering. The proposed developments on the 7400- and 4850-ft levels are presented, along with the plans for adapting Homestake's existing infrastructure for science. The plan differs substantia...

Introduction to Psychology Students' Parental Status Predicts Learning Preferences and Life Meaning

Science.gov (United States)

Lovell, Elyse D'nn; Munn, Nathan

2017-01-01

This study explores Introduction to Psychology students' learning preferences and their personal search for meaning while considering their parental status. The findings suggest that parents show preferences for project-based learning and have lower levels of searching for meaning than non-parents. When parental status, age, and finances were…

National Status and Trends: Guanica, Puerto Rico Contaminants Data

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This project assesses chemical contaminant status in sediment and coral tissues (Porites astroides) collected in and around Guanica Bay, Puerto Rico in 2009....

THE STATUS OF TOPOGRAPHIC MAPPING IN THE WORLD A UNGGIM–ISPRS PROJECT 2012–2015

Directory of Open Access Journals (Sweden)

G. Konecny

2016-06-01

Full Text Available In December 2011, UNGGIM initiated a cooperative project with ISPRS to resume the former UN Secretariat studies on the status of topographic mapping in the world, conducted between 1968 and 1986. After the design of a questionnaire with 27 questions, the UNGGIM Secretariat sent the questionnaires to the UN member states. 115 replies were received from the 193 member states and regions thereof. Regarding the global data coverage and age, the UN questionnaire survey was supplemented by data from the Eastview database. For each of the 27 questions, an interactive viewer was programmed permitting the analysis of the results. The authoritative data coverage at the various scale ranges has greatly increased between 1986 and 2012. Now, a 30 % 1 : 25 000 map data coverage and a 75 % 1 : 50 000 map data coverage has been completed. Nevertheless, there is still an updating problem, as data for some countries is 10 to 30 years old. Private Industry, with Google, Microsoft and Navigation system providers, have undertaken huge efforts to supplement authoritative mapping. For critical areas on the globe, MGCP committed to military mapping at 1 : 50 000. ISPRS has decided to make such surveys a sustainable issue by establishing a working group.

Status Report on the Development of Micro-Scheduling Software for the Advanced Outage Control Center Project

Energy Technology Data Exchange (ETDEWEB)

Germain, Shawn St. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Thomas, Kenneth [Idaho National Lab. (INL), Idaho Falls, ID (United States); Farris, Ronald [Idaho National Lab. (INL), Idaho Falls, ID (United States); Joe, Jeffrey [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2014-09-01

The long-term viability of existing nuclear power plants (NPPs) in the United States (U.S.) is dependent upon a number of factors, including maintaining high capacity factors, maintaining nuclear safety, and reducing operating costs, particularly those associated with refueling outages. Refueling outages typically take 20-30 days, and for existing light water NPPs in the U.S., the reactor cannot be in operation during the outage. Furthermore, given that many NPPs generate between $1-1.5 million/day in revenue when in operation, there is considerable interest in shortening the length of refueling outages. Yet, refueling outages are highly complex operations, involving multiple concurrent and dependent activities that are difficult to coordinate. Finding ways to improve refueling outage performance while maintaining nuclear safety has proven to be difficult. The Advanced Outage Control Center project is a research and development (R&D) demonstration activity under the Light Water Reactor Sustainability (LWRS) Program. LWRS is a R&D program which works with industry R&D programs to establish technical foundations for the licensing and managing of long-term, safe, and economical operation of current NPPs. The Advanced Outage Control Center project has the goal of improving the management of commercial NPP refueling outages. To accomplish this goal, this INL R&D project is developing an advanced outage control center (OCC) that is specifically designed to maximize the usefulness of communication and collaboration technologies for outage coordination and problem resolution activities. This report describes specific recent efforts to develop a capability called outage Micro-Scheduling. Micro-Scheduling is the ability to allocate and schedule outage support task resources on a sub-hour basis. Micro-Scheduling is the real-time fine-tuning of the outage schedule to react to the actual progress of the primary outage activities to ensure that support task resources are

New York State Energy Research and Development Authority. Research projects` update project status as of March 31, 1997

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-07-01

This report provides an update of the New York State Energy Research and Development Authority (NYSERDA) program. The NYSERDA research and development program has five major areas: industry, buildings, energy resources, transportation, and environment. NYSERDA organizes projects within these five major areas based on energy use and supply, and end-use sectors. Therefore, issues such as waste management, energy products and renewable energy technologies are addressed in several areas of the program. The project descriptions presented are organized within the five program areas. Descriptions of projects completed between the period April 1, 1996, and March 31, 1997, including technology-transfer activities, are at the end of each subprogram section.

Project planning and management techniques of the fast-paced TMX-Upgrade construction

International Nuclear Information System (INIS)

Seberger, C.D.; Chargin, A.K.

1981-01-01

The Tandem Mirror Experiment-Upgrade (TMX-Upgrade) construction will be completed in 18 months at a total cost of $14.5 million. This paper describes the project planning and the management techniques used to complete the TMX-Upgrade within its allocated cost and schedule. In the planning stages of a project, before approval of the proposal, we define major project objectives, create a work breakdown structure (WBS), detail a technical description for each level of the WBS, and provide detailed bottoms-up cost estimates and summary schedules. In the operating phase, which continues throughout the project, we establish budget and schedule baselines. The reporting phase includes The Department of Energy (DOE) reviews of project status at monthly, quarterly, and semiannual intervals. These reports include cost, schedule, manpower, major procurement, and technical status information

NICA project at JINR: status and prospects

International Nuclear Information System (INIS)

Kekelidze, V.D.

2017-01-01

The project NICA (Nuclotron-based Ion Collider fAcility) is aimed to study hot and dense baryonic matter in heavy-ion collisions in the energy range up to 11.0 AGeV . The plan of NICA accelerator block development includes an upgrade of the existing superconducting (SC) synchrotron Nuclotron and construction of the new injection complex, SC Booster, and SC Collider with two interaction points (IP). The heavy-ion collision program will be performed with the fixed target experiment Baryonic Matter at Nuclotron (BM@N) at the beam extracted from the Nuclotron, and with Multi-Purpose Detector (MPD) at the first IP of NICA Collider. Investigation of nucleon spin structure and polarization phenomena is foreseen with the Spin Physics Detector (SPC) at the second IP of the Collider.

Monitored Retrievable Storage (MRS) facility project status

International Nuclear Information System (INIS)

Milner, R.A.; Trebules, V.W.; Blandford, J.B.

1994-01-01

1993 has been yet another year of major change in the Monitored Retrievable Storage (MRS) project. The change in administration has brought a new Secretary of Energy to the Department. Secretary O'Leary has brought a strong leadership background and fresh ideas to address the Department's many complex challenges, including the Civilian Radioactive Waste Management System (CRWMS). Dr. Daniel Dreyfus was named Director of the Office of Civilian Radioactive Waste Management. Mr. Richard Stallings has been named, as the new, Nuclear Waste Negotiator under the Nuclear Waste Policy Act, Amendments of 1987. The overall mission of the Office of Civilian Radioactive Waste Management (OCRWM) has not changed. OCRWM is tasked with finding technically sound, environmentally responsible and economically viable solutions to spent nuclear fuel and high-level radioactive waste storage and disposal

R&D status of linear collider technology at KEK

Science.gov (United States)

Urakawa, Junji

1992-02-01

This paper gives an outline of the Japan Linear Collider (JLC) project, especially JLC-I. The status of the various R&D works is particularly presented for the following topics: (1) electron and positron sources, (2) S-band injector linacs, (3) damping rings, (4) high power klystrons and accelerating structures, (5) the final focus system. Finally, the status of the construction and design studies for the Accelerator Test Facility (ATF) is summarized.

Current status and future prospects of Japanese national project on coated conductor development and its applications

Energy Technology Data Exchange (ETDEWEB)

Shiohara, Y. [Superconductivity Research Laboratory, ISTEC, Shinonome 1-10-13, Koto-ku, Tokyo 135-0062 (Japan)], E-mail: shiohara@istec.or.jp; Yoshizumi, M.; Izumi, T. [Superconductivity Research Laboratory, ISTEC, Shinonome 1-10-13, Koto-ku, Tokyo 135-0062 (Japan); Yamada, Y. [Superconductivity Research Laboratory, ISTEC, Nagoya Coated Conductor Center, 2-4-1, Mutsuno, Atsuta-ku, Nagoya 456-8587 (Japan)

2008-09-15

Four years of the current five-year national project since 2003 for development of coated conductors using Y-system superconductors have passed and lots of remarkable results have been achieved. In this paper, the current status and the future prospect of this project are reviewed. The current national project comprises several groups of national laboratories, universities and private companies. The group of high performance tape development, consisting of Fujikura and SRL-NCCC, has worked on the tape by PLD-REBCO superconducting tapes on the PLD-CeO{sub 2}/IBAD-GZO buffered substrates. The high product of I{sub c} and L equal to 112,166 A m was achieved in the 368 m-304.8 A GdBCO tape whose I{sub c} value is mostly above 350 A/cm-w. The performance under the magnetic fields was also improved up to 42 A at 3 T in a GdBCO short film with doping of ZrO{sub 2}. About 61 m long GdBCO tape with ZrO{sub 2} doping showed a high I{sub c} value of 220 A at self field and 30 A at 3 T. On the other hand, the other group focusing on the low production cost has worked on processes of TFA-MOD and MOCVD, etc. The extremely high I{sub c} value of 735 A/cm-w was attained in the TFA-MOD films on PLD-CeO{sub 2}/IBAD-GZO/Hastelloy C276 substrate by means of using the effect of Ba-poor nominal composition. In the efforts for long tape production, 200 m long tapes with high I{sub c} values of 200 A/cm-w and 205 A/cm-w were obtained by MOD-YBCO/PLD-CeO{sub 2}/IBAD-GZO/Hastelloy C276 and PLD-HoBCO on buffered NiW substrate, respectively. The I{sub c} x L value of the MOD-derived tape was 40,000 A m, which is the highest value in the world by the MOD process. Based on the above achievements on the coated conductor process development, two new additional goals were set in the project. One is the development for the extremely low cost tape and another is the development of the basic technologies for making the electric power devices including cables, transformers, motors, current

All projects related to | Page 430 | IDRC - International Development ...

International Development Research Centre (IDRC) Digital Library (Canada)

2008-11-03

In 2006, the Institute for Security Studies (ISS) undertook a project entitled Regulation of the Private Security Sector in Africa that was supported by IDRC under project 103396. Start Date: November 3, 2008. End Date: June 25, 2012. Topic: ARMED FORCES, MILITARY PERSONNEL, LEGAL STATUS, REGULATIONS, ...

The PALLAS research and isotope reactor project status

International Nuclear Information System (INIS)

Van Der Schaaf, B.; De Jong, P.

2010-01-01

In the European Union the first generation research reactors is nearing their end of life condition. Several committees recommend a comprehensive set of reactors in the EU, amongst them the replacement for the HFR research and isotope reactor in Petten: PALLAS. The business case for PALLAS supports a future for a research and isotope reactor in Petten as a perfect fit for the future EU set of test reactors. The tender for PALLAS started in 2007, following the EU rules for tendering complex objects with the competitive dialogue. This procedure involved an extensive consultation phase between individual tendering companies and NRG, resulting in definitive specifications in summer 2008. The evaluation of offers, including conceptual designs, took place in summer 2009. At present NRG is still active in the acquisition of the funding for the project. The licensing path has been started in autumn 2009 with a initiation note on the environmental impact assessment, EIA. The public hearings held in the lead to the advice from the national EIA committee for the approach of the assessment. The PALLAS project team in Petten will guide the design and build processes. It is also responsible for the licensing of the building and operation of PALLAS. The team also manages the design and construction for the infrastructure, such as cooling devices, including remnant heat utilization, and utility provisions. A particular responsibility for the team is the design and construction of experimental and isotope capsules, based on launch customer requirements. (author)

The LISS project

International Nuclear Information System (INIS)

Vigdor, S.E.

1996-01-01

A storage ring with internal targets offers a novel, cost-effective and very well-suited environment for pursuing experiments with multi-GeV polarized light-ion beams. The Indiana University Cyclotron Facility is in the late stages of preparing a funding proposal for such a synchrotron/storage ring, called LISS. I review the status, the extensive technical advantages, and the projected physics program of LISS. (orig.)

Positron--Electron Project (PEP)

International Nuclear Information System (INIS)

Rees, J.R.

1977-01-01

PEP, an 18-GeV electron-positron colliding-beam storage ring facility at SLAC, is being built by a team from LBL and SLAC. Construction is under way and completion is scheduled for Fall of 1979. A summary is given of the design of the facility, and the status of the project is reported

Effect of participation in the Fadama–II project on Participants' socio ...

African Journals Online (AJOL)

For most respondents, the socioeconomic status changed positively following participation in the project. Majority of the respondents in the study area participated actively in fadama meetings and other activities involved in project. Benefits derived from taking part in the project were generally high for most respondents (95.5 ...

Wu-Chia-Pi Solution Attenuates Carbon Tetrachloride-Induced Hepatic Injury through the Antioxidative Abilities of Its Components Acteoside and Quercetin

Directory of Open Access Journals (Sweden)

Ching-Chiung Wang

2012-12-01

Full Text Available Wu-Chia-Pi medicated wine, composed nine Chinese medicines soaked in 35% alcohol, is widely used in Asia for its health-promoting functions. However, long-term consumption of alcohol could result in liver dysfunction. In this study, Wu-Chia-Pi solution (WCPS and extract (WCPE were prepared by modification of the principals given by the Committee on Chinese Medicine and Pharmacy in Taiwan. The aim of this study was to explore the protective effect of WCPS against carbon tetrachloride (CCl4-induced liver injury and to clarify its active component(s. Antioxidative effects of the test samples were evaluated via MDA inhibition, catalase activity and DPPH-scavenging assays. HPLC was used to analysis the active components. Results showed that WCPS (1 and 5 mL/kg significantly prevented CCl4-induced liver injury without chronic liver toxicity. Referring to the antioxidative activities, WCPE displayed significant MDA inhibitory and DPPH-scavenging activities with IC50 values of 0.91 ± 0.03 and 0.60 ± 0.04 mg/mL, respectively. Catalase activity was also enhanced by treatment of WCPE, acteoside and quercetin. Therefore, we suggest that acteoside and quercetin are the major contributors to the antioxidative and hepatoprotective activities of WCPS, and a possible mechanism could be mediated through reduction of oxidative stress.