CERN celebrates André Martin’s 80th birthday

CERN Multimedia

2009-01-01

André Martin, pictured at the ceremony held in honour of his 80th birthday. On 27 August 2009 CERN’s Main Auditorium was the venue for a celebration in honour of André Martin’s 80th birthday. Regarded as one of the most important theoretical physicists of his generation, André Martin is one of CERN’s most distinguished figures. The celebration began with a conference, followed by a concert and a reception. After the conference, André Martin made an emotional speech looking back over his fifty-year career and paying tribute to all those who had made important contributions during his time at CERN. "I was extremely happy, and I am very touched by this marvellous celebration you have organised for me. It was a wonderful idea, and I very much enjoyed the concert of Blandine Eynaud and John Devore. My wife, Schu, and I love the music of Gabriel Fauré", he said at the end. André Martin j...

Hanging drop cultures of human testis and testis cancer samples

DEFF Research Database (Denmark)

Jørgensen, Anne; Young, J; Nielsen, J E

2014-01-01

cultured in 'hanging drops' and effects of activin A and follistatin treatment were investigated in seminoma cultures. RESULTS: Testis fragments with normal spermatogenesis or CIS cells were cultured for 14 days with sustained proliferation of germ cells and CIS cells and without increased apoptosis....... Seminoma cultures survived 7 days, with proliferating cells detectable during the first 5 days. Activin A treatment significantly reduced KIT transcript and protein levels in seminoma cultures, thereby demonstrating a specific treatment response. CONCLUSIONS: Hanging drop cultures of human testis...

Andres Ehin Jaapanist Iirini

Index Scriptorium Estoniae

2006-01-01

Andres Ehin valiti Ülemaailmse Haiku Assotsiatsiooni auliikmeks ja kirjaniku inglisekeelset luulekogu "Moose Beetle Swallow" esitleti 2005. aasta Euroopa kultuuripealinnas Corkis Iirimaal. Järgneb: Looming 2006, nr. 2, lk. 311

Lootsikulood... Soomaa...

Index Scriptorium Estoniae

2005-01-01

29. sept. esines Kärdla kultuurikeskuses ühendus Kummutikunst. Kata-Riina Luide esitas mononäidendi "Lootsikulood". Dekoratsiooniks oleva slaidiprogrammi autor on Tiit Leito. Lavastas Kata-Riina Luide. Autor ja puukujude valmistaja Andres Koidu. Kummutikunsti on asutanud Ugala teatri näitleja Kata-Riina Luide ja puukujur Andres Koidu

Oncogenic cancer/testis antigens

DEFF Research Database (Denmark)

Gjerstorff, Morten F; Andersen, Mads H; Ditzel, Henrik J

2015-01-01

Recent developments have set the stage for immunotherapy as a supplement to conventional cancer treatment. Consequently, a significant effort is required to further improve efficacy and specificity, particularly the identification of optimal therapeutic targets for clinical testing. Cancer....../testis antigens are immunogenic, highly cancer-specific, and frequently expressed in various types of cancer, which make them promising candidate targets for cancer immunotherapy, including cancer vaccination and adoptive T-cell transfer with chimeric T-cell receptors. Our current understanding of tumor...... immunology and immune escape suggests that targeting oncogenic antigens may be beneficial, meaning that identification of cancer/testis antigens with oncogenic properties is of high priority. Recent work from our lab and others provide evidence that many cancer/testis antigens, in fact, have oncogenic...

Effect of the anti-androgenic endocrine disruptor vinclozolin on embryonic testis cord formation and postnatal testis development and function.

Science.gov (United States)

Uzumcu, Mehmet; Suzuki, Hiroetsu; Skinner, Michael K

2004-01-01

Vinclozolin is a systemic dicarboximide fungicide that is used on fruits, vegetables, ornamental plants, and turf grass. Vinclozolin and its metabolites are known to be endocrine disruptors and act as androgen receptor antagonists. The hypothesis tested in the current study is that transient embryonic exposure to an anti-androgenic endocrine disruptor at the time of testis determination alters testis development and subsequently influences adult spermatogenic capacity and male reproduction. The effects of vinclozolin on embryonic testicular cord formation in vitro were examined, as well as the effects of transient in utero vinclozolin exposure on postnatal testis development and function. Embryonic day 13 (E13, sperm-positive vaginal smear day = E0) gonads were cultured in the absence or presence of vinclozolin (50-500microM). Vinclozolin treated gonads had significantly fewer cords (P vinclozolin (100 mg/kg/day) between embryonic days 8 and 14 (E8-E14) of development. Testis morphology and function were analyzed from postnatal day (P) 0, pubertal P20, and adult P60. No significant effect of vinclozolin on testis histology or germ cell viability was observed in P0 testis. The pubertal P20 testis from vinclozolin exposed animals had significantly higher numbers of apoptotic germ cells (P vinclozolin exposed males (P vinclozolin exposed animals was higher in adult P60 animals. Observations demonstrate that vinclozolin can effect embryonic testicular cord formation in vitro and that transient in utero exposure to vinclozolin increases apoptotic germ cell numbers in the testis of pubertal and adult animals. This correlated to reduced sperm motility in the adult. In conclusion, transient exposure to vinclozolin during the time of testis differentiation (i.e. cord formation) alters testis development and function. Observations indicate that transient exposure to an anti-androgenic endocrine disruptor during embryonic development causes delayed effects later in adult life

Andres Võsand: hakkan ilmselt elukutseliseks kunstnikuks / Andres Võsand ; intervjueerinud Veiko Visnapuu

Index Scriptorium Estoniae

Võsand, Andres, 1966-

2010-01-01

Intervjuu Saksaamaal elava tennisisti Andres Võsandiga, kelle maalinäitus "Värvireisid" on avatud Kadriorus Kastellaanimaja Galeriis 30.10-28.11.2010. Tegelemisest maalikunstiga, näitusest, reisidest inspireeritud loomingust, tööst tennisetreenerina, tennisekarjäärist. Andmeid A. Võsandi elukäigu kohta

Cystic dysplasia of the testis: a very rare paediatric tumor of the testis.

Science.gov (United States)

Eberli, Daniel; Gretener, Heini; Dommann-Scherrer, Corina; Pestalozzi, Dietegen; Fehr, Jean-Luc

2002-01-01

To describe a case of cystic dysplasia of the testis (CDT), an uncommon cause of scrotal swelling in the pediatric patient. Clinic, therapy, fertility, and radiographic and pathologic findings are discussed and the 30 previously reported cases are reviewed. A 9-year-old boy presented with asymptomatic scrotal swelling. A scrotal ultrasound showed a multicystic scrotal mass in the rete testis and an ipsilateral renal agenesis. The growth in size of the mass forced the authors to perform an operative exploration. Intraoperative findings included a multicystic mass in the rete testis of the right testicle. Testicle-sparing total removal of the multicystic mass was performed and the pathologic examination revealed a benign, multilobulated configuration of the cysts in the region of the rete testis. These findings were similar to those found in previously reported cases of CDT. Ipsilateral renal agenesis is the most common associated anomaly. As a pathogenetic factor, mal-junction of the Wolffian duct in the 5th week of gestation is most creditable. CDT is a rare cause of pediatric scrotal mass. When feasible, a testicle-sparing approach should be considered and all patients should undergo evaluation for associated urologic anomalies.

Les mots du jazz. Retour(s) sur Le Jazz, d'André Schaeffner et André Coeuroy

OpenAIRE

Roueff , Olivier

2001-01-01

International audience; Le Jazz by André Schaeffner and André Cœuroy (1926), the first learned analysis of jazz, signaled an important phase in the reinvention of this music in France, since, through the debates it sparked at the time, it helped change jazz’s identity from an « American » to a « Black American » music with African « roots ». Cœuroy and Schaeffner referred to sorts of music that jazz criticism would have throw out of its pantheon, but their analyses would form the major grids ...

Detection of quantitative trait loci causing abnormal spermatogenesis and reduced testis weight in the small testis (Smt) mutant mouse.

Science.gov (United States)

Bolor, Hasbaira; Wakasugi, Noboru; Zhao, Wei Dong; Ishikawa, Akira

2006-04-01

The small testis (Smt) mutant mouse is characterized by a small testis of one third to one half the size of a normal testis, and its spermatogenesis is mostly arrested at early stages of meiosis, although a small number of spermatocytes at the late prophase of meiosis and a few spermatids can sometimes be seen. We performed quantitative trait locus (QTL) analysis of these spermatogenic traits and testis weight using 221 F2 males obtained from a cross between Smt and MOM (Mus musculus molossinus) mice. At the genome-wide 5% level, we detected two QTLs affecting meiosis on chromosomes 4 and 13, and two QTLs for paired testis weight as a percentage of body weight on chromosomes 4 and X. In addition, we found several QTLs for degenerated germ cells and multinuclear giant cells on chromosomes 4, 7 and 13. Interestingly, for cell degeneration, the QTL on chromosome 13 interacted epistatically with the QTL on chromosome 4. These results reveal polygenic participation in the abnormal spermatogenesis and small testis size in the Smt mutant.

Utopías y nacionalismo cultural en América Latina. La interpretación de Andrés Sabella a la contribución de Mariátegui, Vallejo y Eguren Utopias and Cultural Nationalism in Latin America. Andres Sabella's Interpretation of Mariategui's, Vallejo's, and Eguren's Contributions

Directory of Open Access Journals (Sweden)

José Antonio González Pizarro

2012-06-01

Full Text Available Se hace una relectura de los autores peruanos José Carlos Mariátegui, César Vallejo y José María Eguren, desde la visión del poeta y ensayista chileno Andrés Sabella, poniendo el énfasis en la noción de utopía -como lo no lugar, lo imposible- no solamente en el ámbito político-económico sino desde la construcción de un ''mundo'' donde la imaginación, la ensoñación, pueda edificar en la niñez, una visión contra la fealdad, lo monocromático, estableciendo con fuertes imágenes líricas el ''mundo imposible'' de lo que se estimaba lo ''perdido'' en la infancia. La interpretación de Sabella -al igual que los textos de los autores peruanos- se sitúa en un contexto de la construcción de un nacionalismo cultural en el continente, como correlato de la búsqueda de una identidad latinoamericana expresiva de la diferencia con los Estados Unidos.A re-reading of Peruvian authors José Carlos Mariátegui, César Vallejo, and José María Eguren is made from the view of the Chilean poet and essay writer Andres Sabella, putting emphasis on the notion of utopia -as the non-place, the impossible- not only in the political and economical ambit, but from the construction of a ''world'' where imagination and dreaming may build, during childhood, a view against ugliness and monocromaticity, establishing the ''impossible world'' of what was estimated as ''lost'' during childhood with strong lyric images. Sabella's interpretation -like Peruvian author's texts- lies within the context of a cultural nationalism construction, as a correlation to the search of a Latin American identity expressing the differences with the USA.

Human testis-expressed sequence 101 is limitedly distributed in germinal epithelium of testis and disappears in seminoma

Directory of Open Access Journals (Sweden)

Cong-Cong Shen

2014-01-01

Full Text Available BACKGROUND: Testis-expressed sequence 101 (TEX101 was found to be highly expressed in testis and involved in acrosome reaction in previous studies. Recently, the metastasis suppressor function of TEX101 in cancer was disclosed, but the comprehensive investigation of its expression has rarely been reported. In this study, the expression features of TEX101 in normal human organs and seminoma were systematically analyzed. RESULTS: Immunohistochemistry demonstrated intense staining of TEX101 in human testis tissues; however, its expression in 27 other types of normal human organs, including the ovary, was negligible. Higher expression of TEX101 was observed in the spermatocytes and spermatids of the testis, but relatively lower staining was detected in spermatogonia. Western blotting showed a single TEX101 band of 38 kDa in human testis, but it did not correspond to the predicted molecular weight of its mature form at 21 KDa. Furthermore, we examined seminoma tissues by immunohistochemistry and found that none of the 36 samples expressed TEX101. CONCLUSIONS: Our data confirmed TEX101 to be a testis protein that could be related to the maturation process of male germ cells. The lack of TEX101 in seminoma indicated its potential role in tumor progression. This characteristic expression of TEX101 could provide a valuable reference for understanding its biological functions.

Los derechos de autor sobre obtenciones vegetales

Directory of Open Access Journals (Sweden)

Rosario Silva Gilli

2015-01-01

Full Text Available Contenido: Las creaciones en la agricultura. Los derechos de autor sobre obtenciones vegetales. El Convenio Internacional para la protección de las obtenciones vegetales (París 1961 y sus revisiones de Ginebra 1972, 1978,1991 Objeto de la protección legal. Condiciones del cultivar. Alcance de la protección. La protección de obtenciones vegetales en el Mercosur. Los Derechos de autor en el Mercosur. El Protocolo de Armonización de normas sobre Propiedad Intelectual en el Mercosur. El Acuerdo de Cooperación y facilitación sobre la protección de las obtenciones vegetales en los Estados Partes del Mercosur.  Alcance de la normativa Mercosur. Los Derechos sobre cultivares en Uruguay. Los Derechos de autor como derechos humanos. ¿Derechos de autor vs. derecho de propiedad intelectual? Reflexión final

Andres Tali sõnavõtt ettekannete päeval = Andres Tali's speech given on the lecture day / Andres Tali

Index Scriptorium Estoniae

Tali, Andres, 1956-

2006-01-01

Kaasaegse Kunsti Eesti Keskuse ettekannete päev "Kunstnike moraalsed valikud kultuurikonfliktides" 27.04.2006 Tallinna Kunstihoones. Oma installatsioonist "Pastoraalne pastishsh" ning videost "Vägivald ja propaganda - The Movie" samas 8.04.-28.05.2006 avatud Elin Kardi, Marko Mäetamme, Marco Laimre ja Andres Tali ühisnäitusel "Vägivald ja propaganda"

LITERATURA Y DERECHOS DE AUTOR EN EL CIBERESPACIO

Directory of Open Access Journals (Sweden)

Ana Carolina Sampaio Coelho

2010-01-01

Full Text Available Esta investigación examina la Internet como un medio de comunicación y distribución de la obra de nuevos autores literarios brasileños. Revisamos la historia de la construcción social del autor, desde la tradición oral hasta la contemporaneidad y la adaptación del mercado editorial a los cambios producidos por las nuevas tecnologías de la comunicación. Se establece una comparación entre la publicación que tiene el formato tradicional de papel y los medios digitales. Desde la Teoría de Usos y Gratificaciones, se investigó el sistema de distribución y recepción de estos autores: fue explorado el grado de satisfacción de las relaciones mantenidas con los potenciales lectores de Weblogs y observamos cómo estos autores perciben los derechos de autor en el ciberespacio.

Testis. Strategy for the management of seminoma testis

International Nuclear Information System (INIS)

Fetterly, J.C.M.

1984-01-01

Many years of experience demonstrate the marked radiocurability of seminoma testis with modest radiation dosage, and accordingly large volumes may be radiated without damage to surrounding normal structures. While several histological types of seminoma are described (classical, anaplastic, or spermatocytic) our treatment strategy is identical

Maailmaparandajad / Ole Ry, Susanne Andres

Index Scriptorium Estoniae

Ry, Ole

2012-01-01

Terapeudid Ole Ry ja Susanne Andres räägivad Dr David Berceli loodud TRE (Tension & Trauma Releasing Exercises) harjutuste kasutamise kogemusest erinevate psüühiliste traumade ja pingetega klientide tervise parandamisel

Undescended testis

DEFF Research Database (Denmark)

Hutson, John M.; Vikraman, Jaya; Li, Ruili

2017-01-01

controlled by androgens. The latter phase requires a complex process of migration from the inguinal abdominal wall to the scrotum and is commonly defective, leading to the high incidence (2–4%) of UDT at birth. The clinical examination of babies and infants aims to confirm the persistence of congenital UDT......Undescended testis (UDT) occurs when something goes wrong with testicular descent from high in the abdominal cavity to the scrotum. Normal descent occurs in two steps, with the transabdominal phase controlled by a new testicular hormone, insulin-like hormone 3, and the inguinoscrotal phase...... by 3–6 months, so surgery can be optimally timed at 6–12 months. For those boys who develop acquired UDT later in childhood, the ‘ascending’ testis often needs surgery between 5 years and 10 years, so all boys should be screened again for UDT at school entry....

Perfiles de autor en repositorios institucionales

Directory of Open Access Journals (Sweden)

Patricia Genovés

2017-10-01

Full Text Available Este trabajo describe las funciones y utilidades de la implementación de perfiles de autor en repositorios institucionales, como un servicio de valor agregado dirigido a acrecentar su uso entre los miembros de una institución y mejorar la visibilidad de la producción científica alojada en el repositorio. Incluye un relevamiento de servicios de perfiles de autor implementados en repositorios institucionales argentinos y extranjeros. Advierte que, ante el establecimiento de mandatos nacionales de depósito, la necesidad de contar con repositorios institucionales fuertes y sostenibles en el tiempo es aún mayor que antes. Integrar a los repositorios las funcionalidades de los sistemas curriculares y de gestión de información científica y tecnológica es un camino para lograr esa fortaleza, y los perfiles de autor son el resultado visible de dicha integración. Señala que el beneficio que representa para un autor contar con un perfil público en el repositorio de su institución es equivalente al beneficio que para una institución representa contar con un repositorio digital, en términos de ventaja competitiva, valor añadido, incremento de la visibilidad y facilidades de recuperación y acceso a la producción generada.

Possible Factors that Affect Testis Volume in Varicocele Patients

Directory of Open Access Journals (Sweden)

Ozay Demiray

2015-06-01

Conclusion: Left varicocele degree is associated with decrease in testis volume. There was no relationship between testis volume and body mass index or smoking habit. Early varicocele diagnosis is important to protect testis volume. [Cukurova Med J 2015; 40(2.000: 233-238

Vi har uddelegeret forbruget og nydelsen til Netflix og de andre teknologigiganter

DEFF Research Database (Denmark)

Bak Herrie, Maja

2018-01-01

https://www.information.dk/debat/2018/05/uddelegeret-forbruget-nydelsen-netflix-andre-teknologigiganter......https://www.information.dk/debat/2018/05/uddelegeret-forbruget-nydelsen-netflix-andre-teknologigiganter...

Cafe Lyon = Cafe Lyon / Andres Labi

Index Scriptorium Estoniae

Labi, Andres, 1977-

2013-01-01

Cafe Lyon (Meistri 22, Tallinn) sisekujundusest. Autorid: Janno Roos, Andres Labi, Kristel Jakobson (Ruumilabor). Prantsuse Lütseumi direktori Lauri Leesi arvamus. Disainibüroo Ruumilabor lühitutvustus

Detection in testis, epididymis and ovary

Indian Academy of Sciences (India)

For the first time, we demonstrate that beyond the oviduct,Ovgp1 mRNA is expressed in the testis, epididymis and ovary, but not in the uterus, cervix, vagina, breast, seminalvesicles and prostate gland. In the testis, Ovgp1 mRNA was localized in the cells at the base of seminiferous tubules(most likely, Sertoli cells), while the ...

Reisid rohelistes aedades / Ülle Grishakov

Index Scriptorium Estoniae

Grišakov, Ülle, 1953-

2000-01-01

Monet' aiast Givernys, La Villette, Andre Citroeni ja Bercy pargist Pariisis, kaktuseaedadest Lõuna-Prantsusmaal, Prantsuse Rivierast, Villandry renessansiaiast, Versailles' pargist (autor Andre le Notre), frantsiskaanlaste kloostri aiast Itaalias Toskaanas. 12 illustratsiooni

Andres Tolts 60 : omanäoliste vaikelude imeline maailm / Andres Tolts ; intervjueerinud Tiina Kolk ; kommenteerinud Jaan Elken

Index Scriptorium Estoniae

Tolts, Andres, 1949-2014

2009-01-01

Andres Toltsi näitused "Asjad" Hobusepea galeriis 12. oktoobrini, "Näitus" Tallinna Kunstihoones 25. oktoobrini, "Varane Tolts" Haus galeriis 13. novembrini. Pikemalt näitusest "Näitus", kuraator Harry Liivrand

Compedios: Sobre los Autores de los Archivos Científicos

Directory of Open Access Journals (Sweden)

Juan Mendoza Vega

1990-12-01

Full Text Available

Académico Juan Mendoza Vega. En el competitivo mundo moderno de la ciencia, la publicación de artículos científicos es actividad no sólo importante sino de las más estimadas; con ella se transmiten a la comunidad científica los resultados de las investigaciones, se dan a conocer las reflexiones, comentarios o desarrollos sobre esos temas y se presentan perspectivas para el futuro; pero también sirven los artículos científicos como renglones fundamentales en el currículo de los profesionales, que en esa forma pueden mostrar presuntamente su capacidad de trabajo, su creatividad y productividad original. El ser autor de artículos científicos se ha tornado logro importante, hasta el punto de que en ciertos ambientes se tiene como axioma la frase “Publicar o Morir”, por supuesto en el sentido académico.

Esta sitt1ación ha permitido el surgimiento de vicios que se empezaron a notar hace ya más de 10 años, pero cuya ocurrencia parece incrementar, si juzgamos por el número de publicaciones que analizan esos fenómenos en los años más recientes.

Especialmente importante resulta el artículo en que el doctor Gustavo A. Silva, funcionario de la Organización Panamericana de la Salud (OPS analiza los problemas de la “Autoría Múltiple” y la “Autoría Injustificada”, y que fue publicado en la edición de febrero de 1990 por el Boletín de la Oficina Sanitaria Panamericana. De acuerdo con el doctor Silva, la costumbre de publicar artículos con la firma de varios autores aumentó notoriamente en el decenio 1979-1988; en efecto, entre 1959 y 1968, el 62.77% de 795 artículos tenían un solo autor y el 6.7 más de cinco autores, pero la proporción cambió a 30.8 con un solo autor, 45.9 entre dos y cuatro autores y 23.2 con cinco autores o más, en el último decenio arriba aludido.

Por supuesto, en muchos casos se justifica la presencia de múltiples autores al frente de un trabajo especialmente complejo o

Development and descent of the testis in relation to cryptorchidism

DEFF Research Database (Denmark)

Virtanen, Helena E; Cortes, Dina; Rajpert-De Meyts, Ewa

2007-01-01

The testis descends in two phases. Animal studies suggest, that the transabdominal descent of the testis depends on the insulin-like hormone 3 (INSL3). Androgens are important in the inguinoscrotal testicular descent in animals and humans. In general, the cause of cryptorchidism is unknown...... and the aetiology is possibly multifactorial. Histological changes in cryptorchid testes demonstrate disturbed development. Conclusion: Since testicular descent is regulated by testis-derived hormones, cryptorchidism may reflect a functional defect of the testis....

Geim, Prof. Sir Andre Konstantin

Indian Academy of Sciences (India)

Fellow Profile. Elected: 2015 Honorary. Geim, Prof. Sir Andre Konstantin FRS. Date of birth: 21 October 1958. Address: Royal Society Research Professor, University of Manchester, Oxford Road, Manchester M13 9PL, UK Contact: Office: (+44-161) 275 4120. Email: geim@manchester.ac.uk. YouTube; Twitter; Facebook ...

El naturalista Alejando de Humboldt, Cavanilles y Juan Andrés

Directory of Open Access Journals (Sweden)

María-Rosario MARTÍ MARCO

2009-11-01

Full Text Available RESUMEN: Tras una breve introducción en la que se traza un paralelismo entre el erudito Juan Andrés y el naturalista Alejandro de Humboldt, se presenta una síntesis de la relevancia del viaje científico de Humboldt iniciado en España. Las referencias sobre la figura y trabajo de Humboldt y, en menor medida, sobre Cavanilles en la gran obra total de Andrés demuestran el vigor intelectual de éste, quien subraya muchos de los elementos fundamentales del legado humboldtiano.ABSTRACT: This paper begins with a brief introduction to the similarities between the scholar Juan Andrés and the naturalist Alexander von Humboldt and continues with a summary of the relevance of Humboldt’s scientific expedition which began in Spain. The references to Humboldt’s persona and endeavours, and to a lesser extent to Cavanilles, in all of Andrés’ great works demonstrate the intellectual ability of the author who pinpoints many of the fundamental aspects of Humboldt’s legacy.

Graafikatriennaali peapreemia Andres Talile

Index Scriptorium Estoniae

2001-01-01

Tallinna XII graafikatriennaali preemiad: grand prix - Andres Tali; 3 võrdset preemiat - Janne Laine, Leonards Laganovskis, Peeter Laurits; diplomid - Lynne Allen, Lucrecia Urbano, Vladimir Tshaika, Zora Stanè, Endi Poskovic, Päivikki Kallio; EKM preemia - Tif Bitmap; Tallinna linna preemia - Ülle Marks ja Jüri Kass; eripreemiad: - J. Laine (Eesti Pank), Vive Tolli (Paletti Eesti AS), Martins Ratniksh, Juris Boiko, T. Bitmap (Balteco AS). Žürii koosseis

File list: His.Adl.10.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: His.Adl.05.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: His.Adl.20.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: His.Adl.50.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: ALL.Adl.50.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Adl.50.AllAg.Testis dm3 All antigens Adult Testis SRX390502,SRX390501,SRX390503...,SRX017856,SRX017854 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.50.AllAg.Testis.bed ...

Effective Condition for Whole Testis Cryopreservation of Endangered Miho Spine Loach (Cobitis choii) Through the Optimization of Mud Loach (Misgurnus mizolepis) Whole Testis Cryopreservation Condition.

Science.gov (United States)

Kim, J J; Nam, Y K; Bang, I C; Gong, S P

　　BACKGROUND: Miho spine loach (Cobitis choii) is an endangered Korean endemic fish. Whole testis cryopreservation is a good way for species preservation, but needs to the sacrifice of a large number of fish to optimize the freezing condition. Considering this limitation, a surrogate fish species was used for the protocol development. This study was to establish the effective condition for Miho spine loach whole testis cryopreservation by optimizing the conditions for whole testis cryopreservation in an allied species, mud loach (Misgurnus mizolepis). The condition for whole testis cryopreservation was optimized in mud loach first, and then the optimal condition was applied to Miho spine loach testes. The optimal condition for mud loach testis cryopreservation consists of the freezing medium containing 1.3 M dimethyl sulfoxide, 6% fetal bovine serum and 0.3 M trehalose, -1 C/min cooling rate and 26 degree C thawing temperature, which also permits effective cryopreservation of Miho spine loach testes. An effective cryopreservation condition for whole testis of the endangered Miho spine loach has been established by using mud loach as a surrogate fish.

An oncological view on the blood-testis barrier

NARCIS (Netherlands)

Bart, J; Groen, HJM; van der Graaf, WTA; Hollema, H; Hendrikse, NH; Vaalburg, W; Sleijfer, DT; de Vries, EGE

The function of the blood-testis barrier is to protect germ cells from harmful influences; thus, it also impedes the delivery of chemotherapeutic drugs to the testis. The barrier has three components: first, a physicochemical barrier consisting of continuous capillaries, Sertoli cells in the tubular

Suicide in men with testis cancer.

Science.gov (United States)

Alanee, S; Russo, P

2012-11-01

Depression, anxiety and aggression are documented in testis cancer patients and can result in death from suicides; however, their risk of suicide is not defined. We report suicide rates among testis cancer patients in the USA and determine factors associated with higher rates. We used the Surveillance, Epidemiology, and End Results (SEER) database maintained by the National Cancer Institute to identify patients diagnosed with testis cancer between 1995 and 2008. Multivariate analysis was used to assess factors affecting suicide rate. Among 23,381 patients followed for 126,762 person-years, suicide rate was 26.0 per 100,000 person-years, with the average corresponding rate in the US population aged 25-44 years being 21.5 per 100,000 person-years; the calculated standardised mortality ratio for death by suicide was 1.2 [95% confidence interval (CI): 1.1-2.1]. The standardised mortality ratio for suicide was 1.5 (95% CI: 1.1-2.1) in ages less than 30 years, and 1.8 (95% CI: 1.3-2.4) in men of races other than White and Black. Other patient and disease characteristics were not predictive. In conclusion, patients with testis cancer have a 20% increase in the risk of suicide over that of the general population, and races other than White and Black and younger patients may commit suicide at higher rates. © 2012 Blackwell Publishing Ltd.

Igale inimesele oma inspektor? / Andre Nõmm

Index Scriptorium Estoniae

Nõmm, Andre

2007-01-01

Finantsinspektsiooni finantsjärelevalve divisjoni juhataja Andre Nõmm on seisukohal, et finantsinspektsiooni ülesanne ei ole valvata iga kodaniku finantsriski maandamist, vaid vastutust peab kandma iga inimene ise. Ometi on riigi eesmärk tõsta oma kodanike teadlikkust laenuturul valitsevatest ohtudest

André François Boshoff

African Journals Online (AJOL)

Campbell Murn

1945-2016) and pay tribute to him. An only child, André spent most of his childhood in very remote areas of southern Africa due to his magistrate father's various postings. Such locations, for example coastal. Transkei and the Caprivi Strip, instilled ...

File list: Oth.Gon.10.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: Oth.Gon.50.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: ALL.Adl.20.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Adl.20.AllAg.Testis dm3 All antigens Adult Testis SRX017857,SRX390502,SRX390501...,SRX017856,SRX390503,SRX017854 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.20.AllAg.Testis.bed ...

File list: ALL.Adl.10.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Adl.10.AllAg.Testis dm3 All antigens Adult Testis SRX017857,SRX017854,SRX017856...,SRX390502,SRX390501,SRX390503 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.10.AllAg.Testis.bed ...

File list: ALL.Adl.05.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Adl.05.AllAg.Testis dm3 All antigens Adult Testis SRX017854,SRX017856,SRX017857...,SRX390503,SRX390501,SRX390502 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.05.AllAg.Testis.bed ...

Thyroid Hormone Role and Economy in the Developing Testis.

Science.gov (United States)

Hernandez, Arturo

2018-01-01

Thyroid hormones (TH) exhibit pleiotropic regulatory effects on growth, development, and metabolism, and it is becoming increasingly apparent that the developing testis is an important target for them. Testicular development is highly dependent on TH status. Both hypo- and hyperthyroidism affect testis size and the proliferation and differentiation of Sertoli, Leydig, and germ cells, with consequences for steroidogenesis, spermatogenesis, and male fertility. These observations suggest that an appropriate content of TH and by implication TH action in the testis, whether the result of systemic hormonal levels or regulatory mechanisms at the local level, is critical for normal testicular and reproductive function. The available evidence indicates the presence in the developing testis of a number of transporters, deiodinases and receptors that could play a role in the timely delivery of TH action on testicular cells. These include the thyroid hormone receptor alpha (THRA), the MCT8 transporter, the TH-activating deiodinase DIO2, and the TH-inactivating deiodinase DIO3, all of which appear to modulate testicular TH economy and testis outcomes. © 2018 Elsevier Inc. All rights reserved.

File list: His.Gon.10.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: His.Gon.50.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available His.Gon.50.AllAg.Testis mm9 Histone Gonad Testis SRX803711,SRX118394,SRX803710,SRX8...SRX671900,SRX671899,SRX185788 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/His.Gon.50.AllAg.Testis.bed ...

File list: Pol.Gon.10.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: Pol.Gon.05.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: Pol.Gon.20.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: His.Gon.20.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available His.Gon.20.AllAg.Testis mm9 Histone Gonad Testis SRX118394,SRX803711,SRX803710,SRX3...SRX112973,SRX185799,SRX185788 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/His.Gon.20.AllAg.Testis.bed ...

Hanging drop cultures of human testis and testis cancer samples: a model used to investigate activin treatment effects in a preserved niche.

Science.gov (United States)

Jørgensen, A; Young, J; Nielsen, J E; Joensen, U N; Toft, B G; Rajpert-De Meyts, E; Loveland, K L

2014-05-13

Testicular germ cell tumours of young adults, seminoma or non-seminomas, are preceded by a pre-invasive precursor, carcinoma in situ (CIS), understood to arise through differentiation arrest of embryonic germ cells. Knowledge about the malignant transformation of germ cells is currently limited by the lack of experimental models. The aim of this study was to establish an experimental tissue culture model to maintain normal and malignant germ cells within their niche and allow investigation of treatment effects. Human testis and testis cancer specimens from orchidectomies were cultured in 'hanging drops' and effects of activin A and follistatin treatment were investigated in seminoma cultures. Testis fragments with normal spermatogenesis or CIS cells were cultured for 14 days with sustained proliferation of germ cells and CIS cells and without increased apoptosis. Seminoma cultures survived 7 days, with proliferating cells detectable during the first 5 days. Activin A treatment significantly reduced KIT transcript and protein levels in seminoma cultures, thereby demonstrating a specific treatment response. Hanging drop cultures of human testis and testis cancer samples can be employed to delineate mechanisms governing growth of normal, CIS and tumorigenic germ cells retained within their niche.

Prevalence of Undescended Testis and its Associated Factors ...

African Journals Online (AJOL)

Prevalence of Undescended Testis and its Associated Factors among under-fives seen at Reproductive and Child Health Clinic in Ifakara, Tanzania. ... The male sexual differentiation and development is important for the normal reproductive life span. Similarly, risk of carcinoma of testis will be prevented, if early diagnosis of ...

File list: ALL.Gon.20.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: ALL.Gon.05.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: ALL.Gon.10.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: ALL.Gon.50.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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Screening for Y microdeletions in men with testicular cancer and undescended testis

DEFF Research Database (Denmark)

Bor, Pinar; Hindkjaer, Johnny; Kølvraa, Steen

2006-01-01

PURPOSE: To investigate a possible association between testicular cancer or undescended testis and Y microdeletions. METHODS: It was designed as a retrospective clinical study. A total of 225 men with testicular cancer or undescended testis were included to study. Fertile men (n = 200) were...... cases showed a single STS missing of marker sY153 and sY139 in testicular cancer (6/185) and undescended testis (1/40) patients, respectively. CONCLUSIONS: Since no contiguous, real Y microdeletions were found in the study population, it seems that Y microdeletions are not a likely common etiological...... cause of poor spermatogenesis in testicular cancer and undescended testis. However, it remains to be determined whether men having a single STS missing have a risk of developing testis cancer or having undescended testis....

File list: ALL.Gon.10.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Gon.10.AllAg.Testis mm9 All antigens Gonad Testis SRX118383,SRX112538,SRX118394...ERX144545,ERX144553,SRX118378,SRX118389,SRX112536,ERX144532,SRX112537 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Gon.10.AllAg.Testis.bed ...

File list: ALL.Gon.20.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Gon.20.AllAg.Testis mm9 All antigens Gonad Testis SRX118394,SRX349391,SRX803711...SRX112541,SRX118388,SRX118389,ERX144545,ERX144532,SRX112536,SRX112537 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Gon.20.AllAg.Testis.bed ...

File list: ALL.Gon.05.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Gon.05.AllAg.Testis mm9 All antigens Gonad Testis SRX803711,SRX118383,SRX118371...ERX144553,SRX803713,SRX838550,ERX144545,ERX144532,SRX112536,SRX112537 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Gon.05.AllAg.Testis.bed ...

Correlation of the size of undescended testis with its location in various age groups

Energy Technology Data Exchange (ETDEWEB)

Taqvi, S R.H.; Akhtar, J; Batool, T; Farhat, M [National Inst. of child Health, Karachi (Pakistan). Dept. of Peadiatrics; Tabassum, R [National Inst. of Child Health, Karachi (Pakistan). Dept. of Radiology

2006-09-15

To assess the correlation of the size of undescended testis with its location in children of various age groups, per- operatively. Children presenting with undescended testis at surgical outpatient were recruited. Physical examination and relevant investigations (haemoglobin, ultrasound for location and size of testes) were performed. Patients were divided randomly into three age groups, group I (8 months - 2.5 years), group II (2.6 - 8 years), group III (8.1-13 years). At orchiopexy location and size of undescended testis were noted. Patients were further sub-divided into groups according to peroperative location of undescended testis, group A (intra-abdominal), group B (intra-canalicular), group C (distal to superficial inguinal ring - pubic). Where no testis was found, a separate group D was assigned. The size of undescended testis at different locations in various age groups was compared with reference to normal descended testicular size in the respective age group, for statistical significance. ANOVA test was used for intergroup comparison for the size of undescended testis and Student t- test was applied for comparison with reference to normal values of the size of testis. A total of 102 patients with undescended testis were included in the study. The total number of 107 testicular units were assessed. Group I had 28, group II, 41 and group III, 38 testes. There were 24 intra-abdominal, 68 intra-canalicular and 12 pubic in location. In 3 cases, no testis was found at exploration. We found no statistically significant difference amongst groups (p-value=0.090) between the size of the undescended testis at different peroperative locations. The size of undescended testis grew with the age as undescended testis of larger size were found in older age group as compared to younger age group. By applying Student t-test, we did not find statistically significant difference in relation to the size of undescended testis in various age groups in comparison to the

Correlation of the size of undescended testis with its location in various age groups

International Nuclear Information System (INIS)

Taqvi, S.R.H.; Akhtar, J.; Batool, T.; Farhat, M.; Tabassum, R.

2006-01-01

To assess the correlation of the size of undescended testis with its location in children of various age groups, per- operatively. Children presenting with undescended testis at surgical outpatient were recruited. Physical examination and relevant investigations (haemoglobin, ultrasound for location and size of testes) were performed. Patients were divided randomly into three age groups, group I (8 months - 2.5 years), group II (2.6 - 8 years), group III (8.1-13 years). At orchiopexy location and size of undescended testis were noted. Patients were further sub-divided into groups according to peroperative location of undescended testis, group A (intra-abdominal), group B (intra-canalicular), group C (distal to superficial inguinal ring - pubic). Where no testis was found, a separate group D was assigned. The size of undescended testis at different locations in various age groups was compared with reference to normal descended testicular size in the respective age group, for statistical significance. ANOVA test was used for intergroup comparison for the size of undescended testis and Student t- test was applied for comparison with reference to normal values of the size of testis. A total of 102 patients with undescended testis were included in the study. The total number of 107 testicular units were assessed. Group I had 28, group II, 41 and group III, 38 testes. There were 24 intra-abdominal, 68 intra-canalicular and 12 pubic in location. In 3 cases, no testis was found at exploration. We found no statistically significant difference amongst groups (p-value=0.090) between the size of the undescended testis at different peroperative locations. The size of undescended testis grew with the age as undescended testis of larger size were found in older age group as compared to younger age group. By applying Student t-test, we did not find statistically significant difference in relation to the size of undescended testis in various age groups in comparison to the

Undesended testis: How extensive should the work up be?

Directory of Open Access Journals (Sweden)

Shera Altaf

2010-01-01

Full Text Available Aim: The aim of this study was to highlight various anomalies associated with undescended testis and to determine how much work up is necessary for this condition. Material and Methods: The study was conducted in the department of Pediatric Surgery SKIMS Srinagar, Kashmir. All patients between 0-14 years of age who attended out patient department (OPD from January 2002 to December 2003 with maldescent of testes were included in the study. Detailed relevant history and physical examination findings were recorded in all the cases. Baseline investigations were performed along with ultrasonography of the abdomen. In relevant cases other investigations like intravenous urography, micturating cystourethrography, CT scan and laparoscopy were performed as and when indicated. Results: A total of 250 cases of undescended testis were registered during this period. Maximum number of cases were in the age group of 5-10 years. In 130 (52% cases the right testis was undescended while 75 (30% had left sided undescended testis and 45 (18% had bilateral undescended testis. Maldescended testis comprised 11% of the admissions. The majority of cases were having gestational age of 37 weeks or more. The associated anomalies picked up on investigations included duplication of upper urinary tract (3.2%, hydronephrosis and polycystic kidney (0.8% each, horseshoe kidney, ectopic kidney, crossed renal ectopia (0.4% each Posterior urethral valves, Prune belly syndrome (0.4% and spina bifida (0.4%. On detailed clinical examination of genitalia several abnormalities were picked which included hydrocele, hypospadias, hernia, chordee, micropenis and ambiguous genitalia. Conclusion: We recommend ultrasonography to be done in all cases of undescended testis in addition to a thorough history and physical examination. Intravenous pyelography, micturating cystourethrogram, CT scan and other investigations should be performed selectively based on history, physical examination or

File list: DNS.Emb.20.AllAg.Embryonic_testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available DNS.Emb.20.AllAg.Embryonic_testis mm9 DNase-seq Embryo Embryonic testis SRX1156635 ...http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/DNS.Emb.20.AllAg.Embryonic_testis.bed ...

Molecular cloning and characterization of a novel human testis ...

Indian Academy of Sciences (India)

Molecular cloning and characterization of a novel human testis-specific gene by use of ... pared against 70 other libraries, and the hits showing >10- fold differences .... proteins or testis-development-related proteins such as TSP-. NY, TPX1 ...

Tehnikahuviline juht ootab töötajalt ausust / Andres Haamer ; interv. Urve Vilk

Index Scriptorium Estoniae

Haamer, Andres, 1942-

2008-01-01

Overall Eesti nõukogu esimees Andres Haamer vastab oma lapsepõlve, haridusteed, karjääri, AS-i Overalli asutamist, oma tööülesandeid ning ühiskondlikus elus osalemist puudutavatele küsimustele. Kommenteerib Valdo Kalm. Lisa: Andres Haamer; Edu võtmed

La Sociedad de Autores Españoles (1899-1932

Directory of Open Access Journals (Sweden)

Raquel Sánchez García

2002-01-01

Full Text Available Durante ia úitima parte dei sigio xix ios autores españoies iniciaron un movimiento asociativo en defensa de sus derechos como profesionales. El proceso culminó en la fundación de la Sociedad de Autores Españoles (precedente de la actual Sociedad General de Autores Españoles. El objetivo principal de la SAE fue conseguir para los autores la administración y gestión de los derectios derivados de sus composiciones musicales y teatrales, lo que tuvo una gran importancia en un momento en que se estaban transformando las formas de ocio en nuestro país. Estas páginas pretenden llevar a cabo un repaso de su organización, sus logros y su evolución desde 1899 hasta 1932.During the last part of xix century, Spanish authors started a movement looking after their rights as professionals in pursuit of assoclations to defend them. The process finished in the foundation of the Sociedad de Autores Españoles (precedent of the SGAE. The principal objective of the SAE was to obtain the right to manage and to negotiate their own works and compositions. This was a very important sucess because of the change of leisure in Spain. In these pages, I will try to study the organization, the achievements and the evolution of the SAE from 1899 to 1932.

Initial Development of an Electronic Testis Rigidity Tester

Directory of Open Access Journals (Sweden)

Petros Mirilas

2011-01-01

Full Text Available We aimed to develop our previously presented mechanical device, the Testis Rigidity Tester (TRT, into an electronic system (Electronic Testis Rigidity Tester, ETRT by applying tactile imaging, which has been used successfully with other solid organs. A measuring device, located at the front end of the ETRT incorporates a tactile sensor comprising an array of microsensors. By application of a predetermined deformation of 2 mm, increased pressure alters linearly the resistance of each microsensor, producing changes of voltage. These signals were amplified, filtered, and digitized, and then processed by an electronic collector system, which presented them as a color-filled contour plot of the area of the testis coming into contact with the sensor. Testis models of different rigidity served for initial evaluation of ETRT; their evacuated central spaces contained different, increasing glue masses. An independent method of rigidity measurement, using an electric weight scale and a micrometer, showed that the more the glue injected, the greater the force needed for a 2-mm deformation. In a preliminary test, a single sensor connected to a multimeter showed similar force measurement for the same deformation in these phantoms. For each of the testis models compressed in the same manner, the ETRT system offered a map of pressures, represented by a color scale within the contour plot of the contact area with the sensor. ETRT found certain differences in rigidity between models that had escaped detection by a blind observer. ETRT is easy to use and provides a color-coded “insight“ of the testis internal structure. After experimental testing, it could be valuable in intraoperative evaluation of testes, so that the surgeon can decide about orchectomy or orcheopexy.

El derecho del autor asalariado en Argentina

Directory of Open Access Journals (Sweden)

Augusto H. L. Arduino

2013-11-01

Full Text Available El autor contratado bajo relación de dependencia laboral en la Argentina no se encuentra regulado en la legislación sobre derecho de autor. La ley número 11723 no contempla la figura, y la reforma de la ley número 25.036 en su art. 2 solo hace referencia a los programas de computación realizados en virtud de un contrato laboral. No obstante, la ley de patentes número 24481 modificada por ley número 24572, ha regulado la cuestión de los derechos de explotación de patentes de invención, mediando relación contractual. Asimismo se ha regulado en ley número 20.744 lo relativo a las invenciones del trabajador. En la ley de patentes de invención se regula la situación del inventor contratado o asalariado. El derecho laboral y la propiedad intelectual en general, y en particular el derecho de autor son de naturaleza diversa y tienen regulaciones específicas con principios jurídicos propios. Por ello, se abordará cada temática desde su generalidad a fin de arribar al tratamiento del problema planteado.

André B. Muller (25.9.1918-1.4.2006)

Science.gov (United States)

West, R. M.

2006-06-01

With great sadness, we have learned about the death of André Muller on 1 April, at the age of 87. Living in retirement in his native Holland since 1983, he was one of ESOs true pioneers, an outstanding representative of the select group of European astronomers who succeeded in steering ESO through the difficult initial phases. André was close-ly associated with the entire process, from the first site monitoring programmes in South Africa to the subsequent search in Chile, the decision in favour of the La Silla site, as well as the management of ESOs early activities in Chile, includ-ing the construction of the headquarters and observatory and the installation of the first generation of ESO telescopes. Few persons, if any, have been so inti-mately connected to the setting-up of ESOs facilities and it would be impossible to list in detail all of the services André performed for the organisation with such great expertise and zeal during his long career.

Efek ekstrak testis terhadap jumlah implantasi dan jumlah anak pada mencit (Mus musculus

Directory of Open Access Journals (Sweden)

Sri Puji Astuti Wahyuningsih

2012-02-01

Full Text Available Extract of testis contains the testis specific proteins. The testis proteins may raise immune responses. The immune responses arethe antibodies against testis specific anti-protein. The reaction between the antibodies and the sperms can inhibit fertilization. Thisprocess has contraception effects. This research used 24 female and 20 male mice strain Balb/c. The experiment used the completerandom design with 4 concentration treatments (0, 500, 1000, and 2000 μg extracts of testis and 3 replications. Mice were injected 3times with time interval 21 days. After 15 days from the rising of vaginal plug, 3 mice were dissected and counted the implantation. Theothers mice were waited until delivered of the children. The datas were analyzed by ANOVA and LSD (α = 5%. The results showed thatextract of testis did not influence the amount of implantation at the uterus endometrial, but it decreased the amount of children. Theeffective concentration of extract testis is 2000 μg. So, this study showed that the intraperitoneum injection of the extract of testis hadcontraception effects.

utilization of crude testis extract to enhance broiler production

African Journals Online (AJOL)

EKWUEME

0.05) while profit per bird and profit over cost of ... effects of different levels of testis extracts in drinking water on ... water. Treatment A served as the control with no testis extract ..... organized by B. B. Vet. Medical ... Maximizing yield. Poultry Sci.

File list: NoD.Gon.50.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: InP.Gon.10.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: NoD.Gon.05.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: InP.Gon.10.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: InP.Gon.20.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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Lifescience Database Archive (English)

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File list: NoD.Gon.10.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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Lifescience Database Archive (English)

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Lifescience Database Archive (English)

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File list: InP.Gon.50.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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Lifescience Database Archive (English)

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GUÍAS PARA LOS AUTORES

Directory of Open Access Journals (Sweden)

INGRID TORRES

2012-12-01

Full Text Available Los autores que deseen enviar sus publicaciones a la revista Lámpsakos deberán ceñirse a las instrucciones mínimas de formato del manuscrito, y concordar con las condiciones éticas requeridas en las publicaciones. Se proporciona información en los idiomas español e inglés

As marcas de (intersubjetividade nas tiras de André Dahmer: uma análise enunciativa

Directory of Open Access Journals (Sweden)

Lucy Peres Farias

2017-07-01

Full Text Available Dos estudos postulados por Benveniste (1956 compreendemos que desde que nos declaramos locutores, nos apropriando da língua para enunciar, automaticamente implantamos o outro diante de nós, em maior ou menor grau de presença. Este artigo objetiva analisar tirinhas do autor André Dahmer na perspectiva do sujeito e intersubjetividade estudada por Benveniste (1956, explicando de que maneira se dá essa intersubjetividade, explicando os efeitos de sentido que são construídos a partir de marcas de sujeito encontradas. Para tanto, as categorias utilizadas serão, principalmente, as noções de pessoa e não pessoa, de Benveniste (1956, operações de localização, de Culioli (1982, apud CAMPOS, 1994, 1997 e modalidades, segundo Neves (2012. Os resultados obtidos a partir da análise mostraram a ocorrência de algumas marcas mais frequentes que outras, e pudemos perceber que a construção de sentidos de humor e crítica está imbricada às escolhas dessas categorias e marcas nos enunciados, marcas essas importantes para a relação de (intersubjetividade na perspectiva Culioliana.

The effect of microgravity on tissue structure and function of rat testis

Directory of Open Access Journals (Sweden)

Ye Ding

2011-12-01

Full Text Available To explore whether an environment of weightlessness will cause damage to the reproductive system of animals, we used the tail-suspension model to simulate microgravity, and investigated the effect of microgravity on the tissue structure and function of the testis in sexually mature male rats. Forty-eight male Wistar rats weighing 200-250 g were randomly assigned to three groups (N = 16 each: control, tail traction, and tail suspension. After the rats were suspended for 7 or 14 days, morphological changes of testis were evaluated by histological and electron microscopic methods. The expression of HSP70, bax/bcl-2 and AR (androgen receptor in testis was measured by immunohistochemistry. Obvious pathological lesions were present in the testis after the rats were suspended for 7 or 14 days. We detected overexpression of HSP70 and an increase of apoptotic cells, which may have contributed to the injury to the testis. The expression of AR, as an effector molecule in the testis, was significantly decreased in the suspended groups compared to control (P < 0.01. We also observed that, with a longer time of suspension, the aforementioned pathological damage became more serious and some pathological injury to the testis was irreversible. The results demonstrated that a short- or medium-term microgravity environment could lead to severe irreversible damage to the structure of rat testis.

Andres Sütevaka näitus Stockholmis

Index Scriptorium Estoniae

2000-01-01

Sütevaka Andrese abstraktsete maalide näitus Stockholmi Eesti Majas. Sütevaka Andres ja näituse avamisele sõitnud tema loomingu kollektsionäär Matti Milius kohtusid Moderna Museeti direktori David Elliotiga teadvustamaks Tartu ja Pärnu kunstielu.

"Vettpidavad allikad" = "Watertight sources" / Janno Roos, Andres Labi

Index Scriptorium Estoniae

Roos, Janno, 1976-

2013-01-01

Eesti Ajaloomuuseumis avatud näituse kujundasid Janno Roos ja Andres Labi (Ruumilabor). Kuraator Krista Sarv. Graafiline disain: Identity. Eksponeeritud allveeuuringute käigus leitu. Arhitektuuriajaloolase Leele Välja arvamus

Radiation effects of electromagnetic pulses on mouse blood-testis barrier

International Nuclear Information System (INIS)

Hou Wugang; Zhao Jie; Zhang Yuanqiang

2005-01-01

Radiation effects caused by 100 kV/m and 400 kV/m electromagnetic pulse (EMP) irradiations on mouse blood-testis barrier were studied by means of routine HE staining, Lanthanum traced electron microscope and injection of caudal vein with Evans Blue. The EMP irradiation of different dose rates damaged Sertoli's cell and blood-testis barrier of mouse testis in different levels. Severe injuries were observed with the 400 kV/m irradiation group, with apoptosis and necrosis in a large quantity of the spermatogenic cells, shape and structural changes of the Sertoli's cells, and serious injuries to the blood-testis barrier, one day after the irradiation. The basal compartment separated from the adluminal compartment in most of the VIII stage seminiferous epithelium, and a great number of apoptosis and necrosis spermatogenic cells were released into the cavities. Injuries of blood-testis barrier could be observed 21 days after the 400 kV/m irradiation. The injuries of 100 kV/m irradiation groups were less severe than the 400 kV/m groups, in which the damages to the Sertoli's cells, the seminiferous epithelium and blood-testis barrier recovered to some extent 14 days after the irradiation. The authors conclude that EMP irradiation can damage mouse blood-tests barrier. The injuries, and the time for recovery, are related to EMP power intensity. (authors)

Absent testis: does it exist in 46,XY males?

African Journals Online (AJOL)

laparoscopy, the vas and testicular vessels are traced as ... Methods Both Mullerian inhibitory factor and testosterone act locally as ... Surg 9:79–80 c 2013 Annals of Pediatric Surgery. ... Unilateral absent testis should be associated ... Absent testis during groin exploration ... visualized at laparoscopic or open exploration.

Building the mammalian testis

DEFF Research Database (Denmark)

Svingen, Terje; Koopman, Peter

2013-01-01

Development of testes in the mammalian embryo requires the formation and assembly of several cell types that allow these organs to achieve their roles in male reproduction and endocrine regulation. Testis development is unusual in that several cell types such as Sertoli, Leydig, and spermatogonial...

File list: NoD.Gon.50.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: NoD.Gon.20.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available NoD.Gon.20.AllAg.Testis hg19 No description Gonad Testis ERX096851,ERX161924,ERX096...849,ERX096874,ERX096842,ERX096870,ERX096875 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/NoD.Gon.20.AllAg.Testis.bed ...

File list: NoD.Gon.10.AllAg.Testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available NoD.Gon.10.AllAg.Testis hg19 No description Gonad Testis ERX096851,ERX096870,ERX161...924,ERX096849,ERX096875,ERX096874,ERX096842 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/NoD.Gon.10.AllAg.Testis.bed ...

Radiation dose and biological effects to mouse testis from sodium 32P-phosphate

International Nuclear Information System (INIS)

Mian, T.A.; Glenn, H.J.; Haynie, T.P.; Meistrich, M.L.

1982-01-01

Radiation dose to mouse testis was estimated to be about 1.65 rad per μCi of intravenously injected 32 P. This high dose to the organ was due to the incorporation of this isotope into the macromolecules of the testis. Up to 30% of the total testis activity was in DNA molecules. Biologic effects on mouse testis from 32 P were determined by testis weight loss and the decrease in the number of sperm heads in the testis. Number of sperm heads reached a minimum of 1.3% of control 36 days after injection of 3.5 μCi/g body weight of 32 P. Significant decreases in sperm head counts were observed after as little as 0.2 μCi/g body weight of 32 P. (author)

Andre on alati tantsida tahtnud / Anu Mõttus

Index Scriptorium Estoniae

Mõttus, Anu

2009-01-01

Koolitantsu maakonnavoorud on peetud. Igast maakonnast pääsevad piirkonnavooru kuni pooled tantsud. Umbes sama edasipääsuprotsent on ka Andre Laine tantsudel, kelle koolitantsu vaimustus algas Kanepi Gümnaasiumi õpilasena ja kes praeguseks on selle gümnaasiumi tantsupedagoog

File list: ALL.Emb.20.AllAg.Embryonic_testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Emb.20.AllAg.Embryonic_testis mm9 All antigens Embryo Embryonic testis SRX14917...57137,SRX1156635,SRX149168,SRX149172,SRX1175150,SRX149166,SRX149170,SRX1175149 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Emb.20.AllAg.Embryonic_testis.bed ...

File list: ALL.Emb.10.AllAg.Embryonic_testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ALL.Emb.10.AllAg.Embryonic_testis mm9 All antigens Embryo Embryonic testis SRX14917...9169,SRX149166,SRX1175147,SRX957137,SRX1175148,SRX149170,SRX1175150,SRX1175149 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Emb.10.AllAg.Embryonic_testis.bed ...

Rare presentation of a testicular angiofibroma treated with testis sparing surgery.

Science.gov (United States)

Leone, Luca; Fulvi, Paola; Sbrollini, Giulia; Filosa, Alessandra; Caraceni, Enrico; Marronaro, Angelo; Galosi, Andrea B

2016-12-30

Testicular benign tumors are very rare (< 5%). Testicular Angiofibroma (AF) is one of those, however the gold standard of treatment and follow-up is still unclear. A 47 years-old man with only one functioning testis was referred to our clinic for a palpable right testicular mass and atrophic contralateral testis. Patient underwent testis-sparing surgery with inguinal approach and intraoperative frozen sections examination with diagnosis of AF. Final histology confirmed AF. Post-operative follow-up was uneventful. Clinical and ultrasonographic follow-up was negative after 8 months. We report a conservative surgery in a patient with AF of the solitary testis. AF is a benign para-testicular fibrous neoplasm that could be misinterpreted as malignant tumor and treated with orchiectomy. Testis-sparing surgery is recommended in this case with intraoperative pathological examination. The excision of the mass is enough but in front of a possible recurrence a long follow-up is advisable.

Rare presentation of a testicular angiofibroma treated with testis sparing surgery

Directory of Open Access Journals (Sweden)

Luca Leone

2016-12-01

Full Text Available Introduction: Testicular benign tumors are very rare (< 5%. Testicular Angiofibroma (AF is one of those, however the gold standard of treatment and follow-up is still unclear. Case report: A 47 years-old man with only one functioning testis was referred to our clinic for a palpable right testicular mass and atrophic contralateral testis. Patient underwent testis-sparing surgery with inguinal approach and intraoperative frozen sections examination with diagnosis of AF. Final histology confirmed AF. Post-operative follow-up was uneventful. Clinical and ultrasonographic follow-up was negative after 8 months. Conclusion: We report a conservative surgery in a patient with AF of the solitary testis. AF is a benign para-testicular fibrous neoplasm that could be misinterpreted as malignant tumor and treated with orchiectomy. Testis-sparing surgery is recommended in this case with intraoperative pathological examination. The excision of the mass is enough but in front of a possible recurrence a long follow-up is advisable.

Activin receptor subunits in normal and dysfunctional adult human testis

DEFF Research Database (Denmark)

Dias, V; Meachem, S; Rajpert-De Meyts, E

2008-01-01

The cellular sites of activin action and its regulation in the normal and dysfunctional adult human testis are unknown.......The cellular sites of activin action and its regulation in the normal and dysfunctional adult human testis are unknown....

Ectopic Splenic Tissue in the Testis: A Case Report

African Journals Online (AJOL)

Ectopic SplENic tiSSUE iN thE tEStiS associated with bilateral cryptorchidism and hypospadias4. Brasch et al. reported a case involving the right testis5. Ultrasonography, scintigraphy (with technetium-99m) and single positron emission computerized tomography are considered the best diagnostic tools for this condition2,3.

Effect of laminaria japonica polysaccharides (LJP) on radiation damage of testis tissue in male rats

International Nuclear Information System (INIS)

Ren Shicheng; Luo Qiong; Yang Mingliang; Yang Jiajuan; Yan Jun; Li Zhuoneng; Wang Lihong; Cui Xiaoyan

2007-01-01

Objective: To observe the effect of laminaria japonica polysaccharides (LJP) on local radiation damage of testis tissue in male rats. Methods: The Wistar rats were randomly divided into 4 groups: the normal group, the model group, positive control group and LJP treatment group (50 mg·kg -1 ·d -1 ). LJP was applied to the treatment group for 10 d before local irradiation with γ-ray (6.0 Gy). The morphological change of the testis, organ index of testis and epididymides, sperm count, motility rate, superoxide dismutase (SOD) activity and malonic aldehyde (MDA) contents were measured. Results: LJP could make the damaged testis recover to near normal, elevate the organ index of testis and epididymides, promote the sperm count and motility rate, increase the activity of SOD and decrease the contents of MDA in testis tissue. Conclusions: LJP could inhibit testis tissue damage induced by local radiation, hence enhance the significant radioprotective effect to testis tissue. LJP has the conspicuous protective effect on radiation damage of testis tissue. (authors)

2623-IJBCS-Article-Gadji Alahou André

African Journals Online (AJOL)

hp

1. Alahou André Gabazé GADJI1,2*, Ossey Bernard YAPO1, Kouabenan ABO2,. Ladji MEITE1, Agnès Eude Yves GNAGNE1, Satinder Kaur BRAR 3 et. Rajeshwar Dayal TYAGI4. 1Laboratoire des Sciences de l'Environnement (LSE), Unité de ...

Pomeranchuk Prize awarded to André Martin

CERN Multimedia

Jordan Juras

2010-01-01

Professor André Martin has been awarded the I.Ya.Pomeranchuk Prize 2010, alongside Professor Valentine Zakharov.   André Martin, CERN theorist, pictured at the ceremony held in honour of his 80th birthday (August 2009). Established by the Institute of Theoretical and Experimental Physics (ITEP) in memory of an outstanding scientist Isaak Yakovlevich Pomeranchuk, the prize is awarded for the study of analytic properties of the scattering amplitude; which lead to the Froissart—Martin bound on the cross section growth with energy. The prize comes as a great honor for Martin, who was in fact a good friend of Mr. Pomeranchuk, "I am surprised and delighted to learn that I will be receiving the 2010 Pomeranchuk Prize. I was an admirer of Pomeranchuk and we shared a great friendship. I met with him for the last time in Erevan (Armenia) in 1965. As a good-bye, he told me, 'Analyticity exists'. This is precisely what I proved to earn the prize"....

El yo-autor-escritor contemporáneo

Directory of Open Access Journals (Sweden)

Everton Vinicius de Santa

2017-01-01

Full Text Available Esta reflexión se refiere a la figura del autor una vez que esta figura se traslada al medio digital, esto es, a un espacio donde se puede mirárselo de forma permanente. Ese traslado impone algunos cambios en la elaboración de una entidad autorial por parte del escritor, o sea, la persona física, el individuo que escribe, “l’écrivant”, según Roland Barthes. Este paso al medio digital está deslegitimando la figura del autor de nuestros días y, por ende, cambiando el role del escritor contemporáneo. Así, la reacción por parte del escritor está siendo su espectacularización. Discuto este tema desde el concepto de ego-historias, experiencias personales en el texto en primera persona, por medio de algunas características presentes en dos narrativas: O espírito da prosa (2012, de Cristovão Tezza, y La parte inventada (2014, de Rodrigo Frésan. Busco evidenciar cómo los medios digitales, la cultura digital y mediática en general favorecen una reflexión metaliteraria sobre la invención de un “yo-autor-escritor” que satisface la necesidad del exhibicionismo que los medios digitales proporcionan en la construcción de su imagen.

Jumalaema kiriku kellamees tuli Tartu Toome varemetesse / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2007-01-01

13. juulil esietendus Emajõe Suveteatris "Jumalaema kiriku kellamees". Victor Hugo romaani järgi tegi instseneeringu Urmas Lennuk, lavastaja Andres Dvinjaninov. Mängitakse Tartu Toomkiriku varemetes

Kohtumine Oslos / Andres Herkel

Index Scriptorium Estoniae

Herkel, Andres, 1962-

2009-01-01

Autor kommenteerib Oslos toimunud Tšetšeenia eksiilvalitsuse juhi Ahmed Zakajevi ning praeguse Tšetšeenia valitseja Ramzan Kadõrovi esindaja ja parlamendijuhi Duhhvahha Abdurahmanovi kohtumist. Versioonid tulevikuks

Mis on looming.org? : elektrooniline heli / Andres Lõo

Index Scriptorium Estoniae

Lõo, Andres

2004-01-01

Võrguajakirjast www.looming.org, kuhu kogutakse infot põhiliselt kahe jaotuse põhjal: muusika ja helieksperimentalism ning kaasaegne kunst, kunsti ja meediaga seonduv. Idee autorid: Hanno Soans ja Andres Lõo. Ilmunud on looming.orgi esimene muusikakogumik "Lilled algebrale"

Santo André: Integración de Programas para Promover la Inclusión Social

OpenAIRE

Rosana Denaldi

2003-01-01

En este trabajo trataremos del programa "Santo André Más Igual", desarrollado desde 1998 en la ciudad de Santo André ubicada en la Región del Gran ABC, en la Región Metropolitana de San Pablo (RMSP) Brasil.

El patrimonio identitario de la comunidad de San Andrés

Directory of Open Access Journals (Sweden)

Carlos Córdova Martínez

2006-01-01

Full Text Available La identidad y el patrimonio son elementos recurrentes si se quiere defender la cultura frente a un mundo globalizado. Dicha labor debe realizarse de lo local a lo nacional y viceversa. El trabajo aborda el patrimonio de una pequeña comunidad holguinera, el Consejo Popular de San Andrés, cuyo centro es el poblado homónimo. Con un largo devenir histórico, que se remonta a fines del siglo XVI. San Andrés atesora un rico patrimonio, que puede incluirse fundamentalmente dentro de la cultura campesina.

File list: InP.Emb.10.AllAg.Embryonic_testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available InP.Emb.10.AllAg.Embryonic_testis mm9 Input control Embryo Embryonic testis SRX1491...74,SRX149168,SRX957136,SRX149172,SRX149166,SRX1175150,SRX1175149 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.Emb.10.AllAg.Embryonic_testis.bed ...

File list: InP.Emb.50.AllAg.Embryonic_testis [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available InP.Emb.50.AllAg.Embryonic_testis mm9 Input control Embryo Embryonic testis SRX1491...74,SRX149168,SRX149172,SRX1175150,SRX149166,SRX957136,SRX1175149 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.Emb.50.AllAg.Embryonic_testis.bed ...

Tzfp represses the androgen receptor in mouse testis.

Science.gov (United States)

Furu, Kari; Klungland, Arne

2013-01-01

The testis zinc finger protein (Tzfp), also known as Repressor of GATA, belongs to the BTB/POZ zinc finger family of transcription factors and is thought to play a role in spermatogenesis due to its remarkably high expression in testis. Despite many attempts to find the in vivo role of the protein, the molecular function is still largely unknown. Here, we address this issue using a novel mouse model with a disrupted Tzfp gene. Homozygous Tzfp null mice are born at reduced frequency but appear viable and fertile. Sertoli cells in testes lacking Tzfp display an increase in Androgen Receptor (AR) signaling, and several genes in the testis, including Gata1, Aie1 and Fanc, show increased expression. Our results indicate that Tzfp function as a transcriptional regulator and that loss of the protein leads to alterations in AR signaling and reduced number of apoptotic cells in the testicular tubules.

Peaosa nii teatrilaval kui ka kinolinal / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2010-01-01

Natalja Murina-Puustusmaast, kes mängib peaosa Vene Teatri uuslavastuses "Besame mucho", mille Afolf Käis on lavastanud Eduardo de Filippo näidendi "Silinder" järgi, ja Andres Puustusmaa filmis "Rotilõks", mille võtted algavad peagi

Tiskre-Hansu korterelamud / Maarja Kask, Tiit Sild, Kalle Rannula...[jt.

Index Scriptorium Estoniae

2005-01-01

I, II ja III korruse plaan, 4 värv. välisvaadet; projekteerija: KPME Engineering & Design, planeeringu eskiisi autorid Maarja Kask, Tiit Sild, kaasa töötas Kalle Rannula, detailplaneering: Andres Volens, Kalle Rannula, I etapi kortermajade autor Tiit Sild, kaasa töötasid Maret Volens, Andres Volens, Kristo Tihvand

Retrofuturistlik tulevik / Andres Lõo

Index Scriptorium Estoniae

Lõo, Andres, 1978-

2012-01-01

17. septembril NO99 teatris esietendunud kolme teatri - NO99, Münchner Kammerspiele, Lyric Hammersmith Theatre - koostöös valminud lavastusest "Three Kingdoms" ("Kolm kuningriiki"), teksti autor Simon Stephens, lavastaja Sebastian Nübling

Kino, Theater, Fernsehen : André Bazins Publikumstheorie

NARCIS (Netherlands)

Hanich, Julian; Mundhenke, Florian; Weber, Thomas

2017-01-01

What did the great French film theorist André Bazin think of the collective experience in the cinema? What did he write about the influence co-viewers can have on the emotional engagement, the evaluation and the interpretation of a film? In short: What was his audience theory? To be sure, Bazin is

Eesti fond rahastab Vene infotehnoloogiat / Andres Reimer

Index Scriptorium Estoniae

Reimer, Andres

2006-01-01

Martinson Trigon Venture Partners (MTVP) loob uue tarkvarainvesteeringute fondi, mis viib endise NSVL-i alale kuni 780 miljonit krooni, fond võtab sihiks kümmekond uut ettevõtet. MTVP esimese fondi investeeringutest. Fondide juhi Andres Susi selgitusi. Lisa: Martinson Trigon Venture Partners osalusega firmad; Vt. samas: Moskvas pole raha ja geeniused kohtunud

Koolid saavad tagasi algusaegade väärikuse / Mari Rebane

Index Scriptorium Estoniae

Rebane, Mari

2003-01-01

Artur Perna projekteeritud Tallinna 21. keskkooli hoone renoveerimisprojekti autor on Raul Järg, sisekujundaja Toomas Korb, lühtrite disainer Tõnis Vellama. Edgar Johan Kuusiku projekteeritud Lenderi tütarlastegümnaasiumi (Tallinna kesklinna vene gümnaasium) renoveerimisprojekti autor on Andres Põime, sisekujundaja Tiiu Truus

Ärimehed tõid kuu ja päikese Narva-Jõesuusse

Index Scriptorium Estoniae

2009-01-01

2008. a. avatud Meresuu spaa-hotellist, mis ehitati nõukogudeaegse lõpetamata rajatise peale. Arhitektuurse lahenduse autor Andres Põime ja sisekujunduse autor Reet Põime arhitektuuribüroost Studio 3. Wellness-korruse sisekujundaja Liisi Murula. Purskkaevud-lillepeenrad kavandas Kersti Lootus. Omanikud: Aare Kööp, Rene Kuulmann

Concentration of radiolabeled cholesterol in a feminizing adenoma of the testis

International Nuclear Information System (INIS)

Leonard, J.M.; Rudd, T.G.; Gurgess, E.C.; Monda, G.A.

1979-01-01

Quantitative tissue studies demonstrated increased 19-[ 131 I]-iodocholesterol concentration in a feminizing adenoma of the testis. The potential application of iodocholesterol and its isomers in the detection of steroid-secreting neoplasms of the testis and ovary is suggested

Tzfp represses the androgen receptor in mouse testis.

Directory of Open Access Journals (Sweden)

Kari Furu

Full Text Available The testis zinc finger protein (Tzfp, also known as Repressor of GATA, belongs to the BTB/POZ zinc finger family of transcription factors and is thought to play a role in spermatogenesis due to its remarkably high expression in testis. Despite many attempts to find the in vivo role of the protein, the molecular function is still largely unknown. Here, we address this issue using a novel mouse model with a disrupted Tzfp gene. Homozygous Tzfp null mice are born at reduced frequency but appear viable and fertile. Sertoli cells in testes lacking Tzfp display an increase in Androgen Receptor (AR signaling, and several genes in the testis, including Gata1, Aie1 and Fanc, show increased expression. Our results indicate that Tzfp function as a transcriptional regulator and that loss of the protein leads to alterations in AR signaling and reduced number of apoptotic cells in the testicular tubules.

Direito autoral e o livro eletrônico

Directory of Open Access Journals (Sweden)

Helen Beatriz Frota Rozados

2014-06-01

Full Text Available Este artigo discorre sobre os novos desafios decorrentes do livro eletrônico no que tange ao direito autoral. Para tanto, utiliza-se de pesquisa bibliográfica para levantar e analisar as características do direito autoral e as propostas de mudanças na legislação brasileira,e descreve as novas formas de proteção desenvolvidas a fim de disponibilizar as obras ao público bem como proteger os direitos autorais. São abordados o Copyleft, Digital Right Management (DRM e o Creative Commons dentre as novas formas de proteção. Conclui-se que o livro eletrônico tem propiciado uma gama de novas discussões no âmbito do mercado editorial e pelos legisladores, levando a uma necessária reflexão, mais intensa, que possa propiciar efetivas mudanças na legislação sobre direito autoral, mudanças estas que englobem um melhor controle do processo de acesso, uso e divulgação, seja para impedir ações ilegais, uso da informação sem a devida creditação, plágio e ou a proliferação de cópias não permitidas.

Mis siis juhtus Andres Lapeteusega? / Õie Orav

Index Scriptorium Estoniae

Orav, Õie

2011-01-01

Režissöör Grigori Kromanovi filmist "Mis juhtus Andres Lapeteusega?" (Tallinnfilm, 1965). Osades: Einari Koppel, Ita Ever, Heino Mandri, Kaljo Kiisk, Uno Loit, Ada Lundver jt. Lühidalt filmi kohta ilmunud arvustustest. Filmi näeb ETV2-s sarjas "Unustatud filmid"

El concepto de autor en la obra de Gérard Genette

OpenAIRE

Roger, Julien

2009-01-01

El objeto de esta ponencia es, mediante un examen de las ocurrencias del término autor bajo la pluma de Genette, esencialmente en Figures III y Palimpsestes, intentar demostrar que el concepto de autor, lejos de ser deleznable, como para buena parte de la Nouvelle Critique, constituye una llave hermenéutica para entender su obra.

TGF-β superfamily signaling in testis formation and early male germline development.

Science.gov (United States)

Young, Julia C; Wakitani, Shoichi; Loveland, Kate L

2015-09-01

The TGF-β ligand superfamily contains at least 40 members, many of which are produced and act within the mammalian testis to facilitate formation of sperm. Their progressive expression at key stages and in specific cell types determines the fertility of adult males, influencing testis development and controlling germline differentiation. BMPs are essential for the interactive instructions between multiple cell types in the early embryo that drive initial specification of gamete precursors. In the nascent foetal testis, several ligands including Nodal, TGF-βs, Activins and BMPs, serve as key masculinizing switches by regulating male germline pluripotency, somatic and germline proliferation, and testicular vascularization and architecture. In postnatal life, local production of these factors determine adult testis size by regulating Sertoli cell multiplication and differentiation, in addition to specifying germline differentiation and multiplication. Because TGF-β superfamily signaling is integral to testis formation, it affects processes that underlie testicular pathologies, including testicular cancer, and its potential to contribute to subfertility is beginning to be understood. Copyright © 2015 Elsevier Ltd. All rights reserved.

Risk factors for undescended testis.

NARCIS (Netherlands)

Brouwers, M.M.; Bruijne, L.M. de; Gier, R.P.E. de; Zielhuis, G.A.; Feitz, W.F.J.; Roeleveld, N.

2012-01-01

OBJECTIVE: To contribute to the understanding of the etiology of undescended testis (UDT), by exploring a wide range of potential risk factors in a case-referent study. PATIENTS AND METHODS: Cases and referents were recruited at five hospitals and included 200 boys with surgically corrected UDT and

Leiomyoma of Testis –Rare Benign Mimicker of Testicular Malignancy

Directory of Open Access Journals (Sweden)

Asif Baliyan

2017-10-01

Full Text Available Leiomyomas are benign tumours that originate from any organ containing smooth muscles. The testis is an extremely rare site. We report a case of testicular leiomyoma in a 50-year-old. Testis-associated leiomyomas are a benign and rare disease presenting as a painless, slowly-growing mass. Only histological examination with immunohistochemistry can validate the diagnosis.

Effectiveness of testis cancer screening

International Nuclear Information System (INIS)

Feucht, H.

1983-04-01

In the Federal Republic of Germany there are about thousand to two-thousand incidences of testis cancer yearly. The screening (and examination) program currently used for the early detection of cancer includes the screening of malignant tumours of the testis. Since only males 45 years and older are invited to make use of the preventive measures, the most seriously affected age-group between twenty and forty is hereby not considered. The objective of this study is to find out which of the generally conceivable preventive measures could lead to an improvement of the present situation. The analysis shows that, for a diagnostic accuracy of 1 and a participation of 100%, the quantifyable cost of a yearly performed special screening is higher than the quantifyable cost savings achieved. A final judgement of other ways of execution is only possible when the diagnostic accuracy of suitable screening methods and the percentage of the participants of the groups of people concerned are known. (orig.)

La red de co-autores en la Bibliometría mexicana

Directory of Open Access Journals (Sweden)

Cristina Restrepo-Arango

2018-01-01

Full Text Available Se analiza la red de coautorías existentes en las publicaciones sobre las metrías (bibliometría, informetría, cienciometría, patentometría, etc. en México, desde la década de los 70s hasta diciembre de 2012. Se utilizó el análisis de redes sociales a través del software Ucinet 6.0 y Netdraw. Los análisis muestran una red altamente centralizada. La densidad global de la red indica una red de baja densidad comunicacional que hace una utilización efectiva de una quinta parte de los vínculos reales sobre el total de vínculos posibles entre todos los autores de la red. El grado de centralidad identifica once autores como los componentes estructurales de la red de bibliometría mexicana. Los coeficientes del grado de cercanía indican que tanto la lejanía como la cercanía son homogéneas. En relación con el grado de intermediación se encontró que no existe una red ampliamente extendida sino la dominancia de un pequeño grupo de tres autores. La distancia geodésica identificó un único autor bien conectado a otros autores también muy bien posicionados en la red. No se identificaron cliques ni n-cliques en la red de coautoría de la bibliometría mexicana.

Tiskre-Hansu elamud = Tiskre-Hansu Homes / Tiit Sild

Index Scriptorium Estoniae

Sild, Tiit, 1977-

2005-01-01

Projekteerija: KPME Engineering & Design. Planeeringu eskiisi autorid Maarja Kask, Tiit Sild, kaasa töötas Kalle Rannula. Detailplaneering: Andres Volens, Kalle Rannula. I etapi kortermajade autor Tiit Sild, kaasa töötasid Maret Volens, Andres Volens, Kristo Tihvand. Valmis 2004-2005. Ill.: I, II ja III korruse plaan, 4 värv. välisvaadet

Gene expression during testis development in Duroc boars

DEFF Research Database (Denmark)

Lervik, Siri; Kristoffersen, Anja Bråthen; Conley, Lene

2015-01-01

. Nine clusters of genes with significant differential expression over time and 49 functional charts were found in the analysed testis samples. Prominent pathways in the prepubertal testis were associated with tissue renewal, cell respiration and increased endocytocis. E-cadherines may be associated...... with the onset of pubertal development. With elevated steroidogenesis (weeks 16 to 27), there was an increase in the expression of genes in the MAPK pathway, STAR and its analogue STARD6. A pubertal shift in genes coding for cellular cholesterol transport was observed. Increased expression of meiotic pathways...

Surgical treatment and follow up on undescended testis

DEFF Research Database (Denmark)

Thorup, Jørgen Mogens; Cortes, D.

2009-01-01

With skill and ability to control a variety of operative techniques, undescended testes can be placed in the scrotum with 90% success rate in palpable testes and 85% in abdominal testes. Long term results are related also to the variability of the disease. A hypothesis that in cryptorchid testes...... number at birth in some cryptorchid testes and Intratubular Germ Cell Neoplasia seen in early childhood. The hypothesis that the abnormal location of the testis exposes the testis to infertility and malignant transformation is supported by the findings of early treatment lowering the risk of both...

Shielding for Scattered Radiation to the Testis During Pelvic Radiotherapy: Is it worth?

International Nuclear Information System (INIS)

NAZMY, M.S.; El-Taher, M.M.; Attalla, E.M.; El-Hosiny, H.A.; Lotayef, M.M.

2007-01-01

To assess the value of external shielding of the testis during pelvic radiotherapy. Material and Methods: Nineteen patients, receiving radiotherapy to the pelvis with the lower border of the field at the obturator foramen, were randomly selected. A 5 half value layer cerro bent shield was positioned at the inferior border of the field. The dose to the testis was measured with and without the shield. Observations were made regarding the reflex cre master contraction and phantom measurements were done at different distances from the perineum. Results: The mean radiation dose to the testis for patients receiving treatment with no shield was 7.4 cGy (±) and it was 5.7c Gy (±) for patients with external shield, this difference was statistically significant by the paired t test p<0.0001. This accounted for a 22% decrease in the dose received by the testis. The position of the testis with the contraction of the cre master muscle and the dartos fascia after manipulation of the testis during diodes placement changed up to 3.5 cm (mean 1.5). Phantom measurements showed 37% increase in the dose with 2 cm change in the position of the testis to the pelvic direction. Conclusion: External shield at the inferior border of the pelvic field is a simple, easy reproducible, convenient shielding method. Clam-shell scrotal shield is not free of drawbacks, but still its benefits overweigh its harms and should be used with caution

Findings concerning testis, vas deference, and epididymis in adult cases with nonpalpable testes

Directory of Open Access Journals (Sweden)

Coskun Sahin

2011-12-01

Full Text Available In this study, we aimed to state the relationship between testis, epididymis and vas deference, in adult cases with nonpalpable testis. Between January 1996 and December 2009, we evaluated 154 adult cases with nonpalpable testes. Mean age was 23 years (20-27 years. Explorations were performed by open inguinal incision, laparoscopy, and by inguinal incision and laparoscopy together on 22, 131 and 1 patient, respectively. Of all the unilateral cases, 32 were accepted as vanishing testis. In five of these cases, vas deference was ending inside the abdomen, and in the others, it was ending inside the scrotum. In the remaining 99 unilateral and 22 bilateral cases, 143 testes were found in total. Testes were found in the inguinal canal as atrophic in one case, at the right renal pedicle level with dysmorphic testis in one case, and anterior to the internal ring between the bladder and the common iliac vessels at a smaller than normal size in 119 cases. One (0.69% case did not have epididymis. While epididymis was attached to the testis only at the head and tail locations in 88 (61.53% cases, it was totally attached to the testis in 54 (37.76% cases. There is an obviously high incidence rate of testis and vas deference anomalies, where epididymis is the most frequent one. In cases with abdominal testes, this rate is highest for high localised abdominal testes.

TORSION TESTIS : ROLE OF COLOR DOPPLER : A STUDY OF 50 CASES

Directory of Open Access Journals (Sweden)

Anand

2015-09-01

Full Text Available BACKGROUND: T orsion testis is one of the catast r ophic conditions in children and young a d u lts. Traditionally the diagnosis was made clinical presentation and suspicion. Critical decision making is essential to save the testis . OBJECTIVE: To study the usefu lness and efficacy of Doppler ultrasound in correctly diagnosing acute scrotal conditions in children and young adults to save the testis and to avoid negative explorations. METHODS: Over a period of two years 50 patients with acute scrotum were admitted i n general surgery department who underwent Doppler ultrasound scrotum and its efficacy in correctly diagnosing the pathology was analysed. RESULTS: 50 patients with age group <25 years were included in study. Scrotal pain was the most frequent presenting s ymptom of acute scrotum (98% followed by Swelling of the hemiscrolum on the involved side present in 86% of the patients. Doppler ultrasound showed torsion of testis in 18 patients. On Scrotal exploration, torsion of spermatic cord was confirmed in 16 pat ients, one patient had torsion of appendix of testis and the other had Epididymo - orchitis. Thus the sensitivity and specificity of Doppler ultrasonography for testicular torsion was 86.9% and 92.6% respectively. 2 patients with equivocal Doppler findings, but strong clinical suspicion of testicular torsion were explored, and testis was found to be torsed in both two patients. Doppler ultrasonography showed Epididymo - orchitis in 22 patients, torsion of testicular appendage in 2 patients, Idiopathic scrotal edema in one, and in 5 pts no significant pathology found. All twenty patients of epididymo - orchitis, two patients of torsion of testicular appendage, and one patient of idiopathic scrotal edema were managed conservatively. At three weeks follow up, all th e patients were free of symptoms. The sensitivity and specificity of Doppler ultrasonography for epididymo - orchitis was 95% and 100% respectively. CONCLUSIONS: color

Definir al autor. Desde la propiedad intelectual hasta el movimiento derecho y literatura

Directory of Open Access Journals (Sweden)

Julio César Padilla Herrera

2013-12-01

Full Text Available Comúnmente, analizar la definición de autor es una tarea que en investigación jurídica seaborda desde la propiedad intelectual. En aquella, el autor se asemeja a un propietario dederechos exclusivos y excluyentes, con lo cual se fundamenta una noción cerrada. Pero otraforma –quizás más propicia– de análisis se encuentra en la crítica literaria, situada aquí enla disyunción derecho-literatura. Desde esta última se pretenden hacer evidentes algunoselementos interpretativos que den apertura a la noción unívoca que se halla en la propiedadintelectual. Por lo anterior el presente texto analizará la noción de autor que existe en el derechode autor y en un sector de la crítica literaria con dos propósitos fundaméntales: primerocuestionar el paradigma de autonomía del individuo creador/propietario, y, segundo, aportarcriterios adicionales que permitan superar el significado unívoco de la definición de autor.

Pedagogic Juan Andrés Cué Bada's work (1935-1979

Directory of Open Access Journals (Sweden)

Janet Reinaldo-Delgado

2017-06-01

Full Text Available Juan Andrés Cué Bada was born on November 30, 1908 in the province of Las Tunas. He had an active political participation against Machado and Batista, while he dedicated himself to private education. After the triumph of the Cuban Revolution in 1959 he moved to Santiago de Cuba and in 1962 began his professorial course at the Universidad de Oriente until he died in 1979. Because of the lack of knowledge about his figure and his work as a teacher, this article Intends to explain the pedagogical work of Juan Andrés Cué Bada between the years 1935 and 1979.

Gonadotropin Regulation of Retinoic Acid Activity in the Testis

Directory of Open Access Journals (Sweden)

Seyedmehdi Nourashrafeddin

2018-02-01

Full Text Available Initiation of spermatogenesis in primates is triggered at puberty by an increase in gonadotropins; i.e., follicle-stimulating hormone (FSH and luteinizing hormone (LH. Prior to puberty, testis of the monkey contains only undifferentiated germ cells. However, sermatogonial differentiation and spermatogenesis may be initiated prior to puberty after stimulation with exogenous LH and FSH. Retinoic acid (RA signaling is considered to be a major component that drives spermatogonial differentiation. We were interested in evaluating the relative role of LH and FSH, either alone or in combination, in regulating the retinoic acid signaling in monkey testis. Sixteen juvenile male rhesus monkeys (Macaca mulatta were infused with intermittent recombinant single chain human LH (schLH or recombinant human FSH (rhFSH or a combination of both for 11 days. We then analyzed the expression of the several putative RA signaling pathway related genes; i.e. RDH10, RDH11, ALDH1A1, ALDH1A2, CYP26B1, CRABP1, CRABP2, STRA6, STRA8 in the testis after 11 days of stimulation with vehicle, LH, FSH and combination LH/FSH using quantitative real-time PCR (qPCR. The qPCR results analysis showed that administration of gonadotropins affected a significant change in expression of some RA signaling related genes in the monkey testis. The gonadotropins, either alone or in combination dramatically increased expression of CRABP2 (p≤0.001, whereas there was a decrease in ALDH1A2 expression (p≤0.001. Moreover, combined gonadotropin treatment led to the significant decrease in CRABP1 expression (p≤0.05. These findings are the first evidence that the activity of retinoic acid signaling in the monkey testis is regulated through gonadotropins (LH/FSH levels.

Kutseharidust hakkab muutma uus paradigma / André Huigens ; intervjueerinud Veiko Belials

Index Scriptorium Estoniae

Huigens, André

2011-01-01

Intervjuu Luual toimunud rahvusvahelise kutsehariduse alase seminari peaesineja, André Huigensiga, kes on Euroopa kutseõppe arenduskeskuse Cedefop kvalifikatsiooniraamistiku ekspert Hollandi Wellantcollege’ist

MASSIVE QUANTITIES OF PELAGIC Sargassum ON THE SHORES OF SAN ANDRES ISLAND, SOUTHWESTERN CARIBBEAN

Directory of Open Access Journals (Sweden)

Brigitte GAVIO

2015-01-01

Cantidades masivas de Sargassum pelágicos en las costas de San Andrés Isla, Caribe suroccidental Se reporta la llegada de una biomasa inusual de Sargassum flotante, compuesta por las especies S. fluitans y S. natans, a la costa nororiental de la isla de San Andrés. La época y el tamaño del evento nunca habían sido reportados anteriormente para la isla.

Radiation damage to mouse testis cells from [/sup 99m/Tc] pertechnetate

International Nuclear Information System (INIS)

Mian, T.A.; Suzuki, N.; Glenn, H.J.; Haynie, T.P.; Meistrich, M.L.

1977-01-01

The radiation dose and the biologic damage to mouse testis from intravenously administered [/sup 99m/Tc] pertechnetate were studied. The dose was measured for penetrating radiations from /sup 99m/Tc, using calibrated thermoluminescent dosimeters and calculations from the uptake of the nuclide in the testis, and was found to be 4.9 rads per mCi of 99 Tc. The biologic damage was measured by the decrease in the number of sperm heads in the testis, counted both by hemacytometer and by Coulter counter. In preliminary experiments using external gamma radiation from 137 Cs, the number of sperm heads reached a minimum 29 days after irradiation. Twenty-nine days after injection of 5.8 mCi of /sup 99m/Tc, which gives 28 rads to the testis, the number of sperm heads decreased to 70% of control. The biologic effect corresponds to that seen after 40 rads of gamma radiation from 137 Cs. The damage to mouse testis cells from internally administered /sup 99m/Tc as measured in an in vivo system appears to be at least as significant as that from external gamma irradiation, if not more so

Expression and Location of Glucose-regulated Protein 78 in Testis and Epididymis

Directory of Open Access Journals (Sweden)

W Wang

2014-04-01

Full Text Available Objective: To know the role of glucose-regulated protein 78 (GRP78/BiP/HSPA5 in spermatogenesis and its expression and location in the testis and epididymis. Methods: Immunohistochemistry and Western blot were used to detect GRP78 location and expression in the testis and epididymis. Results: Glucose-regulated protein 78 was observed in spermatocytes, round spermatids and interstitial cells of the testis and in principal cells of the epididymis. Glucose-regulated protein 78 was first detected in the rat testis at postnatal day 14. Thereafter, the protein level increased gradually with age and was maintained at a high and stable state after postnatal day 28. In the rat, GRP78 was expressed in the principal cells but not in clear cells of the epididymis. Conclusion: Glucose-regulated protein 78 participates in the process of spermatogenesis.

André-Philip Lemke näitus Tallinnas / Mari Laaniste

Index Scriptorium Estoniae

Laaniste, Mari, 1977-

1998-01-01

Saksa kunstniku André-Philip Lemke (1970) näitus "Üks-üks armsa Jumala kasuks" 17. augustist Saksa Kultuuriinstituudis. Tööd on valgele paberile tavalise sinise pastapliiatsiga kirjutatud-joonistatud

Prügitelevisioonist / Andres Maimik

Index Scriptorium Estoniae

Maimik, Andres, 1970-

2004-01-01

Kodumaiste kommertstelekanalite saated nagu "Vein ja seltskond", "Kaunis kaunimaks", "Nurgakivi", millele autor vastandab "arrogantse rämpsu" Esto TV saadete näol, kus "trash õilistub kõrgema aate kandjaks"

Papillary mesothelioma of the albuginea testis

NARCIS (Netherlands)

Tjandra, B. S.; Daemen, M. J.; Weil, E. H.

1994-01-01

An eleven-year-old boy is presented with symptom of a torsion of the testis. Scrotal exploration revealed a papillary mesothelioma of the tunica albuginea which is extremely rare in childhood. We report 1 case and review the literature

André François Boshoff (1945-2016)

African Journals Online (AJOL)

Campbell Murn

National Herbarium in Pretoria and at Stellenbosch. In 1974 André was awarded a. BSc (honours) postgraduate degree in Wildlife Management at the. University of Pretoria (Eugène. Marais. Chair of. Wildlife. Management). It was during this period that he developed a greater interest in birds, especially in their conservation ...

Haapsalu Gümnaasiumi võimla = Haapsalu Gymnasium Gym / Andres Alver

Index Scriptorium Estoniae

Alver, Andres, 1953-

2001-01-01

Projekteerija: Alver Trummal Arhitektid OÜ. Arhitektid Andres Alver, Sven Koppel, Tarmo Laht, Ulla Mets. Projekt 1998-1999, hoone valmis 2001. 11 ill.: asendi- ja korruse plaan, pikilõige, välis- ja sisevaated

Kommest Auto ostmisest huvitub ka Hillar Teder / Andres Eilart

Index Scriptorium Estoniae

Eilart, Andres

2008-01-01

Kommest Auto ostmise vastu tunnevad huvi suurärimees Andres Sarri, Rootsis Peugeot' sõidukeid müüv Taani päritolu K. W. Bruun Import ja multimiljonär Hillar Teder, kellele kuulub Audisid müüv Reval Auto

ALTERATIONS IN THE DEVELOPING TESTIS TRANSCRIPTOME FOLLOWING EMBRYONIC VINCLOZOLIN EXPOSURE

OpenAIRE

Clement, Tracy M.; Savenkova, Marina I.; Settles, Matthew; Anway, Matthew D.; Skinner, Michael K.

2010-01-01

The current study investigates the direct effects of in utero vinclozolin exposure on the developing F1 generation rat testis transcriptome. Previous studies have demonstrated that exposure to vinclozolin during embryonic gonadal sex determination induces epigenetic modifications of the germ line and transgenerational adult onset disease states. Microarray analyses were performed to compare control and vinclozolin treated testis transcriptomes at embryonic day 13, 14 and 16. A total of 576 di...

Andres Puustusmaa - mees nagu jalgratas ehk Seitseteist kevadist hetke enne Moskva rongi väljumist / Andres Puustusmaa ; interv. Margus Mikomägi

Index Scriptorium Estoniae

Puustusmaa, Andres

2008-01-01

Venemaal tegutseva Eestist pärit režissööri Andres Puustusmaa mängufilm "18-14" esilinastub 10. jaanuaril Eestis. Lisaks tõlge filmi tutvustavast tekstist (www.1814.ru) : "Tsarskoje Selo Kõrilõikaja ja lütseumi kasvandikud". Artikkel rubriigis "Teatriküljed 1/25"

Impact of electronic-cigarette refill liquid on rat testis.

Science.gov (United States)

El Golli, N; Rahali, D; Jrad-Lamine, A; Dallagi, Y; Jallouli, M; Bdiri, Y; Ba, N; Lebret, M; Rosa, J P; El May, M; El Fazaa, S

2016-07-01

Electronic cigarettes (e-cigarettes) are becoming the fashionable alternative to decrease tobacco smoking, although their impact on health has not been fully assessed yet. The present study was designed to compare the impact of e-cigarette refill liquid (e-liquid) without nicotine to e-liquid with nicotine on rat testis. For this purpose, e-liquid with nicotine and e-liquid without nicotine (0.5 mg/kg of body weight) were administered to adult male Wistar rats via the intraperitoneally route during four weeks. Results showed that e-liquid with or without nicotine leads to diminished sperm density and viability, such as a decrease in testicular lactate dehydrogenase activity and testosterone level. Furthermore, quantitative real-time polymerase chain reaction (qRT-PCR) analysis identified a reduction in cytochrome P450 side-chain cleavage (P450 scc) and 17 beta-hydroxysteroid dehydrogenase (17βHSD) mRNA level, two key enzymes of steroidogenesis. Following e-liquid exposure, histopathological examination showed alterations in testis tissue marked by germ cells desquamation, disorganization of the tubular contents of testis and cell deposits in seminiferous tubules. Finally, analysis of oxidative stress status pointed an outbreak of antioxidant enzyme activities such as superoxide dismutase, catalase and gluthatione-S-transferase, as well as an important increase in sulfhydril group content. Taken together, these results indicate that e-liquid per se induces toxicity in Wistar rat testis, similar to e-liquid with nicotine, by disrupting oxidative balance and steroidogenesis.

Sex-biased miRNAs in gonad and their potential roles for testis development in yellow catfish.

Science.gov (United States)

Jing, Jing; Wu, Junjie; Liu, Wei; Xiong, Shuting; Ma, Wenge; Zhang, Jin; Wang, Weimin; Gui, Jian-Fang; Mei, Jie

2014-01-01

Recently, YY super-male yellow catfish had been created by hormonal-induced sex reversal and sex-linked markers, which provides a promising research model for fish sex differentiation and gonad development, especially for testis development. MicroRNAs (miRNAs) have been revealed to play crucial roles in the gene regulation and gonad development in vertebrates. In this study, three small RNA libraries constructed from gonad tissues of XX female, XY male and YY super-male yellow catfish were sequenced. The sequencing data generated a total of 384 conserved miRNAs and 113 potential novel miRNAs, among which 23, 30 and 14 miRNAs were specifically detected in XX ovary, XY testis, and YY testis, respectively. We observed relative lower expression of several miR-200 family members, including miR-141 and miR-429 in YY testis compared with XY testis. Histological analysis indicated a higher degree of testis maturity in YY super-males compared with XY males, as shown by larger spermatogenic cyst, more spermatids and fewer spermatocytes in the spermatogenic cyst. Moreover, five miR-200 family members were significantly up-regulated in testis when treated by 17α-ethinylestradiol (EE2), high dose of which will impair testis development and cell proliferation. The down-regulation of miR-141 and 429 coincides with the progression of testis development in both yellow catfish and human. At last, the expression pattern of nine arbitrarily selected miRNAs detected by quantitative RT-PCR was consistent with the Solexa sequencing results. Our study provides a comprehensive miRNA transcriptome analysis for gonad of yellow catfish with different sex genotypes, and identifies a number of sex-biased miRNAs, some of that are potentially involved in testis development and spermatogenesis.

GPR56 is essential for testis development and male fertility in mice.

Science.gov (United States)

Chen, Guangchun; Yang, Liquan; Begum, Shahinoor; Xu, Lei

2010-12-01

Testis development is critical for male fertility and continuation of the mammalian species. Essential structural components of testes are seminiferous tubules, which are lined by Sertoli cells and provide nutrients and physical protection for the maturation of sperm. Seminiferous tubule formation is initiated in embryos as testis cords and relies on their remodeling for maturation during development. Recently, three-dimensional image analyses showed that testis cords in different parts of embryonic gonads undergo distinct remodeling processes. How this asymmetric remodeling is regulated has not been investigated. We report here that the absence of an adhesion G protein-coupled receptor, GPR56, leads to partial disruption of seminiferous tubules and reduced fertility in male mice. The defects appear to originate asymmetrically in embryonic gonads, but subsequent to the initial establishment of testis cords, suggesting that GPR56 might act to establish a spatial and/or temporal cue for asymmetric cord remodeling during male gonad development. © 2010 Wiley-Liss, Inc.

André Lefevere and his Manipulation School

OpenAIRE

Šmrha, Jan

2015-01-01

This theoretical and historiographical thesis examines the theoretical work of the Translation Studies scholar André Lefevere. It focuses primarily on the analysis of Lefevere's work in the context of the development of Translation Studies (particularly in connection with the development of Descriptive Translation Studies, the formation of the "Manipulation School" and the cultural and sociological turns in Translation Studies). The thesis covers Lefevere's theoretical underpinnings, the grad...

A testis-specific and testis developmentally regulated tumor protein D52 (TPD52)-like protein TPD52L3/hD55 interacts with TPD52 family proteins

International Nuclear Information System (INIS)

Cao Qinhong; Chen Jie; Zhu Li; Liu Yun; Zhou Zuomin; Sha Jiahao; Wang Shui; Li Jianmin

2006-01-01

Tumor protein D52-like proteins (TPD52) are small coiled-coil motif bearing proteins that were first identified in breast cancer. TPD52 and related proteins have been implicated in cell proliferation, apoptosis, and vesicle trafficking. To date, three human TPD52 members had been identified, named hD52 (TPD52), hD53 (TPD52L1), and hD54 (TPD52L2). The most important characteristic of the protein family is a highly conserved coiled-coil motif that is required for homo- and heteromeric interaction with other TPD52-like proteins. Herein, we identified a novel TPD52-like sequence (TPD52L3, or hD55) in human testis using cDNA microarray. Sequence analysis of the deduced protein suggests that hD55 contains a coiled-coil motif and is highly conserved compared with other TPD52-like sequences. Yeast two-hybrid and GST pull-down assays revealed that hD55 interacts with hD52, hD53, hD54, and itself. cDNA microarray detection found that hD55 was expressed at 5.6-fold higher levels in adult testis than in fetal testis. Additionally, the expression profile shows that hD55 is testis-specific, indicating a potential role for hD55 in testis development and spermatogenesis

Eesti Energia esindused = Eesti Energia branches / Andres Labi, Janno Roos

Index Scriptorium Estoniae

Labi, Andres, 1977-

2013-01-01

Eesti Energia klienditeeninduse kontorite sisekujundusest. Autorid: Janno Roos, Andres Labi ja Liisa Põime (Ruumilabor). Visuaalne identiteet: Tank.Teenuste disain: Urmas Pastarus. ESLi aastapreemiate žürii esimehe Kaido Kivi ning žürii liikme Raivo Puusepa arvamused

Finalmente, um novo texto de autores brasileiros sobre teorias de marketing

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José Rafael Motta Neto

2007-12-01

Full Text Available  Até recentemente, o ensino de marketing nas universidades e faculdades brasileiras tinha o suporte bibliográfico de autores clássicos da literatura da área. Pontificavam nomes como Philip Kotler, o mais tradicional dos autores de marketing, com suas obras em português nos servindo desde os anos 60, até obras mais recentes como a de Gilbert A. Churchill Jr e J. Paul Peter, passando por consagrados autores nacionais como Marcos Cobra e Alexandre Las Casas. Obviamente estamos falando de obras que fazem referência à teoria do marketing, abordando integralmente o conteúdo que permite ao leitor entender todos os conceitos desta área, numa seqüência didaticamente adequada, além de facilitar, para o professor, a transmissão da matéria, como na disciplina de Administração Mercadológica.

Los derechos de autor en internet

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Marcelo Bauzá

2014-10-01

Full Text Available Contenido: Un punto de partida: prudencia e interrogantes. La propiedad intelectual y su constante readaptación. El derecho autoral en breves trazos. La conmoción de internet. Tipología de obras autorales en el nuevo contexto. Problemas autorales relacionados con internet. Las protecciones técnicas. Propiedad intelectual y comercio electrónico. Regulaciones jurídicas incipientes. Las disidencias o alternativas a la P.I. en internet. Reflexiones finales

The oligosaccharidic content of the glycoconjugates of the prepubertal descended and undescended testis: lectin histochemical study.

Science.gov (United States)

Gheri, Gherardo; Sgambati, Eleonora; Thyrion, Giorgia D Zappoli; Vichi, Debora; Orlandini, Giovanni E

2004-01-01

The saccharidic content of the glycoconjugates has been studied in the descended the undescended testes of a 8 years old boy. For this purpose, a battery of seven HRP-conjugated lectins (SBA, DBA,PNA,WGA,UEAI, LTA and ConA) was used. D-galactose-N-acetyl-D-galactosamine and alpha-L-fucose sugar residues, which were present in the cytoplasm of the Sertoli cells of the normally positioned prepubertal testis, were not detected in the same cells of the undescended testis. The Leydig's cells of the descended testis appeared characterized by N-acetyl-D-glucosamine which was absent in the rare and atrophic Leydig's cells of the cryptorchid testis. Differences in sugar residues distribution between the descended and the undescended testis were also detected in the lamina propria of the seminiferous tubules. Peritubular myoid cells in the undescended testis only reacted with PNA, after neuraminidase digestion, thus revealing the presence of D-galactose (beta1-->3)-N-acetyl-D-galactosamine and sialic acid. In this study a complete distributional map of the sugar residues of the glycoconjugates in the descended and undescended prepubertal testis is reported.

DE LA MUERTE DEL AUTOR A LA MUERTE DEL ARTISTA: REFLEXIÓN CRÍTICA PARA UN DEBATE EN TORNO A LA FIGURA DEL AUTOR

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Ricardo Arcos-Palma

2011-04-01

Full Text Available La "muerte del autor" se ha convertido en el paradima de la postmodernidad. El siguiente ensayo realiza un análisis crítico de tal expresión y las consecuencias de su aplicación en el mundo del arte contemporáneo. La tesis planteada es la siguiente: la muerte del autor trae consigo la muerte del artista y del crítico, figuras representativas de la autoridad. Tales muertes generan el nacimiento de una nueva figura de poder que es el curador. Con este texto se pretende aportar elementos de reflexion para un debate, que apenas comienza, en torno a la figura del curador.

Shedding Light on the Sea: André Morel's Legacy to Optical Oceanography

Science.gov (United States)

Antoine, David; Babin, Marcel; Berthon, Jean-François; Bricaud, Annick; Gentili, Bernard; Loisel, Hubert; Maritorena, Stéphane; Stramski, Dariusz

2014-01-01

André Morel (1933-2012) was a prominent pioneer of modern optical oceanography, enabling significant advances in this field. Through his forward thinking and research over more than 40 years, he made key contributions that this field needed to grow and to reach its current status. This article first summarizes his career and then successively covers different aspects of optical oceanography where he made significant contributions, from fundamental work on optical properties of water and particles to global oceanographic applications using satellite ocean color observations. At the end, we share our views on André's legacy to our research field and scientific community.

Perekonnad hoiavad kontrolli tuntud suurfirmade tegevuse üle / Andres Reimer

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Reimer, Andres

2005-01-01

Andres Haamer räägib oma perefirma Overall Eesti loomisest. Uniprindi-Unipressi omanikud Sirje ja Andrus Reinsoo hindavad koos oma äri peatrumpideks täielikku usaldust ja teineteisemõistmist. Lisad: Maailma legend: Rockefellerid; Eesti legend: Puhkid

L'autografia d'autore Cambiamenti nella realizzazione e nella concezione del libro dal XII secolo all'invenzione della stampa

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Micol Long

2012-06-01

Full Text Available Si ritiene a volte che l'invenzione della stampa abbia innescato il cambiamento nel modo di concepire l'oggetto libro, segnando il passaggio dall'idea medievale a quella moderna. Occorre però tenere presente che esiste un'importante evoluzione interna al medioevo e che l'invenzione della stampa, per quanto fondamentale, è da inserire all'interno di questo processo più ampio, che a partire dal XII secolo circa trasforma l'uso e la funzione stessa della scrittura, rivoluziona il modo di leggere e di conseguenza il libro stesso, sia concettualmente sia come oggetto fisico. L'approccio scelto per questo studio mira a risalire alle radici culturali dei cambiamenti nelle pratiche del lavoro intellettuale e, viceversa, a indagare se e come tali cambiamenti abbiano potuto influenzare, attraverso le opere stesse, la cultura dell'epoca. Il fenomeno oggetto specifico dell'indagine è l'autografia letteraria d'autore che, eccezionale nell'alto medioevo, è testimoniata da una nuova e ininterrotta serie di casi a partire dall'XI-XII secolo, per poi diffondersi nei secoli successivi. Il panorama culturale della fine del medioevo appare dunque caratterizzato dalla tensione tra una ricorrente aspirazione all'individualizzazione del rapporto tra l'autore e il suo testo, che si realizzava in un modello di produzione libraria basato su uno stretto controllo dell'autore sul prodotto finale, dal punto di vista sia filologico-testuale sia grafico e materiale, e l'opposta tendenza all'allentamento del controllo dell'autore sulla propria opera, come naturale conseguenza di una sempre più vasta circolazione dei testi ma anche di una diversa concezione del ruolo autoriale. It is generally believed that the invention of printing triggered a cultural change, marking the passage between the medieval idea of the book and the modern one. It should be noted, though, that there was an important evolution through the Late Middle Ages, and that the printing revolution

Arhitektuuriteos võimendatud representatsiooni ajastul = Work of Architecture in the Age of Amplified Representation / Epp Lankots

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Lankots, Epp, 1976-

2005-01-01

Meedia ja arhitektuuri suhetest, meediarepresentatsioonide mõjuvõimust. Autor analüüsib arhitektuuri propageerimise ja edendamise eesmärgil valminud filme: "Maja 2002", "Maja 2003", "Maja 2004" (režissöör Peeter Brambat), "Surm Veneetsias" (autorid Marianne Kõrver, Andres Maimik, Rain Tolk, 2004), "OP! 43 maja" (autor Märten Vaher). Bibliograafia lk. 18

Protective effect of Zingiber officinale extract on rat testis after cyclophosphamide treatment.

Science.gov (United States)

Mohammadi, F; Nikzad, H; Taghizadeh, M; Taherian, A; Azami-Tameh, A; Hosseini, S M; Moravveji, A

2014-08-01

Decreasing the side effects of chemotherapy in testis has been the subjects of many studies. In this study, the protective effects of Zingiber officinale extract on rat testis were investigated after chemotherapy with cyclophosphamide. Histological and biochemical parameters were compared in cyclophosphamide-treated rats with or without ginger extract intake. Wistar male rats were randomly divided into four groups each 10. The control group received a single injection of 1 ml isotonic saline intraperitoneally. The Cyclophosphamide (CP) group received a single dose of cyclophosphamide (100 mg kg(-1) BW) intraperitoneally. CP + 300 and CP + 600 groups received orally 300 or 600 mg of ginger extract, respectively, for a period of 6 weeks after cyclophosphamide injection. The morphologic and histological structure of the testis was compared in different groups of the rats. Also, factors like malondialdehyde, reactive oxygen species, total antioxidant capacity and testosterone level were assessed in blood serum as well. Our results showed that although ginger extract could not change testis weight, malondialdehyde (MDA) and ROS, but antioxidant and testosterone levels in serum were increased significantly. Also, an obvious improved histological change was seen in CP + 300 and CP + 600 groups in comparison with CP group. These protective effects of ginger on rat testis after cyclophosphamide treatment could be attributed to the higher serum level of antioxidants. © 2013 Blackwell Verlag GmbH.

Vabadus teeb rikkaks / Andres Arrak

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Arrak, Andres, 1958-2017

2005-01-01

Autor analüüsib Eesti majandusvabadust kahe edetabelipõhjal: ühte koostab alates 1996. aastast Kanadas asuv Frazeri Instituut, teist USA-s asuv Heritage Foundation ja majandusajakiri The Wall Street Journal. Diagramm: Majandusvabaduse indeksi muutus mullu Euroopa Liidus

'Sidun' e 'Creuza de mâ' di Fabrizio De André (1940–1999. La svolta etnica del cantautore genovese attraverso l’analisi di due canzoni esemplari

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Vanna Lovato

2014-01-01

Full Text Available L’album Creuza de mâ (1984 di Fabrizio De André, composto e registrato grazie alla fondamentale collaborazione del musicista Mauro Pagani, rappresenta un unicum nella storia della canzone italiana, ed è più in generale un buon esempio di canzone d’autore moderna rielaborata secondo parametri musicali e linguistici diversi dagli standard della canzone di consumo tipici dell’epoca in cui l’album venne pubblicato, anticipando di quasi un decennio in Italia la moda della cosiddetta world music. Pur confermandosi ad oggi uno dei migliori esempi di ‘contaminazione’ tra canzone popolare –– rappresentata qui dall’uso del dialetto genovese –– e tradizione musicale mediterranea , nel 1984 il disco fu accolto in modo tiepido dal pubblico , ma ottenne  subito il plauso della critica e di molti colleghi ed estimatori, italiani e non; ricordiamo, tra gli altri, gli apprezzamenti fatti nel corso degli anni dal musicista inglese David Byrne.

Energy Transition Initiative: Island Energy Snapshot - San Andres and Providencia (Fact Sheet); NREL(National Renewable Energy Laboratory)

Energy Technology Data Exchange (ETDEWEB)

None

2015-03-01

This profile provides a snapshot of the energy landscape of the Archipelago of San Andres, Providencia, and Santa Catalina (unpopulated), also known as San Andres and Providencia, which is equidistant between Costa Rica and Jamaica and 775 kilometers northwest of Colombia. The archipelago is part of Colombia, though Nicaragua has also laid claim to it.

Long non-coding RNA expression profiling of mouse testis during postnatal development.

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Jin Sun

Full Text Available Mammalian testis development and spermatogenesis play critical roles in male fertility and continuation of a species. Previous research into the molecular mechanisms of testis development and spermatogenesis has largely focused on the role of protein-coding genes and small non-coding RNAs, such as microRNAs and piRNAs. Recently, it has become apparent that large numbers of long (>200 nt non-coding RNAs (lncRNAs are transcribed from mammalian genomes and that lncRNAs perform important regulatory functions in various developmental processes. However, the expression of lncRNAs and their biological functions in post-natal testis development remain unknown. In this study, we employed microarray technology to examine lncRNA expression profiles of neonatal (6-day-old and adult (8-week-old mouse testes. We found that 8,265 lncRNAs were expressed above background levels during post-natal testis development, of which 3,025 were differentially expressed. Candidate lncRNAs were identified for further characterization by an integrated examination of genomic context, gene ontology (GO enrichment of their associated protein-coding genes, promoter analysis for epigenetic modification, and evolutionary conservation of elements. Many lncRNAs overlapped or were adjacent to key transcription factors and other genes involved in spermatogenesis, such as Ovol1, Ovol2, Lhx1, Sox3, Sox9, Plzf, c-Kit, Wt1, Sycp2, Prm1 and Prm2. Most differentially expressed lncRNAs exhibited epigenetic modification marks similar to protein-coding genes and tend to be expressed in a tissue-specific manner. In addition, the majority of differentially expressed lncRNAs harbored evolutionary conserved elements. Taken together, our findings represent the first systematic investigation of lncRNA expression in the mammalian testis and provide a solid foundation for further research into the molecular mechanisms of lncRNAs function in mammalian testis development and spermatogenesis.

Raio Piiroja : mängijatest ei suudetud maksimumi pigistada / Andres Kalvik

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Kalvik, Andres, 1982-

2007-01-01

Vt. ka Postimees : na russkom jazõke 19. nov., lk. 13. Eesti koondis võlgneb EM-valikturniiri viimase kohtumise 2:0 Andorra üle suuresti Andres Operile. Kommenteerib Andorra koondise peatreener David Rodrigo

Miocene and Pleistocene mollusks from San Andres Island (Caribbean Sea, Colombia) and Paleogeographic considerations

International Nuclear Information System (INIS)

Diaz M, Juan Manuel; Garcia Llano, Cesar Fernando

2010-01-01

San Andres Island is the largest emerged portion of the oceanic archipelago of San Andres and Providencia, southwestern Caribbean Sea; it originated as a coralline atoll during Miocene times. The central and highest part of the island consists of a calcareous crest, the San Andres Formation, formed by Neogene lagoonal and reefal deposits. This crest is surrounded by a calcareous platform of Pleistocene age (San Luis Formation) which emerges only along the island coast, whereas its most part is submerged and covered by a Recent reef complex. Fossil material of molluscs from these two formations was collected in various sites throughout the island and taxonomically identified. In the four sites sampled in the San Andres Formation, material belonging to 19 gastropod and 37 bivalve species was obtained, most of them relatively well represented in other geologic formations of the Caribbean region that are stratigraphically situated between the upper Miocene and the middle Pliocene. Some elements occurring in this formation, such as Ostrea haitiensis, Meretrix dariena and Siphocypraea henekeni, were widely distributed in the Caribbean Miocene Province. In the San Luis Formation, material belonging to 18 gastropod and 11 bivalve species was obtained, most of them also represented in the Recent molluscan fauna of the region. The estimated age of this formation is Sangamonian, hence corresponding to similar formations occurring in Grand Cayman, Jamaica, Hispaniola, the Netherlands Antilles and other Caribbean islands, with which it also shows a great similarity in the composition of the molluscan fauna.

Macrophages Contribute to the Spermatogonial Niche in the Adult Testis

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Tony DeFalco

2015-08-01

Full Text Available The testis produces sperm throughout the male reproductive lifespan by balancing self-renewal and differentiation of spermatogonial stem cells (SSCs. Part of the SSC niche is thought to lie outside the seminiferous tubules of the testis; however, specific interstitial components of the niche that regulate spermatogonial divisions and differentiation remain undefined. We identified distinct populations of testicular macrophages, one of which lies on the surface of seminiferous tubules, in close apposition to areas of tubules enriched for undifferentiated spermatogonia. These macrophages express spermatogonial proliferation- and differentiation-inducing factors, such as colony-stimulating factor 1 (CSF1 and enzymes involved in retinoic acid (RA biosynthesis. We show that transient depletion of macrophages leads to a disruption in spermatogonial differentiation. These findings reveal an unexpected role for macrophages in the spermatogonial niche in the testis and raise the possibility that macrophages play previously unappreciated roles in stem/progenitor cell regulation in other tissues.

Gaza võitmatu armaada / Andres Laasik

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Laasik, Andres, 1960-2016

2010-01-01

Katsest viia laevadega humanitaarabi Gaza sektorisse. Autor on arvamusel, et kui Vabaduse laevastik ongi saavutanud soovitu ja murdnud blokaadi, siis uus tasakaal pole julgeoleku mõttes sugugi kindlam

[Rets. rmt. : Glucksmann, Andre. Ouest contre Ouest. Pariis, 2003] / Malle Talvet

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Talvet, Malle

2004-01-01

Prantsuse filosoofi Andre Glucksmanni raamat "Ouest contre Ouest" ehk "Lääs Lääne vastu" käsitleb rahvusvahelisi sündmusi 2002/2003, eelkõige Iraaki, terrorismi, Ameerika Ühendriike ja Prantsusmaad

Kliimamuutuste mõju laboratoorium / Andres Tarand

Index Scriptorium Estoniae

Tarand, Andres, 1940-

2001-01-01

Segadused Ida-Aafrika riikides, nende põhjused. Tabel: Ida-Aafrika riikide mõned arengunäitajad: Etioopia, Sudaan, Somaali, Burundi, Rwanda, Uganda, Tanzania, Keenia. Autor: Rahvaerakond Mõõdukad. Parlamendisaadik

Sobre "La tortuga" de Andrés Holguin

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José Puben

1961-04-01

Full Text Available Andrés Holguín no es el primero y, ciertamente, no será el último escritor contemporáneo que, interesado por el problema de los animales que han logrado dimensión fantástica, se proponga, con interés intelectual, analizar e investigar la dimensión e importancia de un animal en la historia de la cultura.

Eestlane juhib Ukrainas EBRD investeeringuid / Andre Küüsvek ; interv. Henrik Ilves

Index Scriptorium Estoniae

Küüsvek, Andre

2008-01-01

Seni Euroopa Rekonstruktsiooni- ja Arengupanga (EBRD) Kasahstani osakonda juhtinud Andre Küüsvek valiti juhtima EBRD investeeringuid Ukrainas. Tänavu on plaanis investeerida Ukrainas 1,5 mld. dollarit

A Natureza e a gênese das Minas do Sul nos livros de André João Antonil e Sebastião da Rocha Pita

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Francisco Eduardo de Andrade

2006-06-01

Full Text Available Este artigo trata do sentido cosmológico da Natureza, em voga na época das representações do barroco (séculos XVII e XVIII, quando aplicado ao contexto novo da América portuguesa com o descobrimento das Minas de ouro. Dois autores da Bahia foram significativos das primeiras visões de Natureza e da sociedade das Minas do ouro: André João Antonil e Sebastião da Rocha Pita. Ambos produziram obras sobre a gênese do espaço minerador, buscando, de algum modo, integrá-lo a uma história providencial da colonização portuguesa. Para isso, investiram em temas e imagens que, além de condicionados por evidentes interesses políticos e econômicos dos plantadores do litoral, refletem os vínculos discursivos dos coloniais eruditos.This work deals with the cosmological sense of the Nature, which has been intensively studied at the time of baroc representations (17th and 18th centuries, applied to the Portuguese America new context of gold mines discoveries. Two authors from Bahia were very important to the early views on the Nature and on the society in gold mines: André João Antonil and Sebastião da Rocha Pita. Both have made studies about the genesis of the mining space in such a way to integrate it in an opportune history of the Portuguese colonization. To do this, they dealed mainly with subjects and images which reveal discourse links of colonial wise persons, and also which were influenced by political and economical interests of the coastal farmers.

Exclusive nuclear location of estrogen receptors in Squalus testis.

Science.gov (United States)

Callard, G V; Mak, P

1985-01-01

An estrogen (E)-binding molecule having both occupied and unoccupied sites is restricted to nuclear subfractions in the testis of the spiny dogfish (Squalus acanthias). We investigated the hypothesis that a species characterized by high body-fluid osmolarity (1010 mosM) has an estrogen receptor (ER) that binds to chromatin with high affinity and consequently resists redistribution during tissue processing. Although the steroid binding and sedimentation properties of the Squalus nuclear ER conformed to those of classical ER, its elution maximum from DNA-cellulose was unusually high (0.55 M NaCl). A tendency to adhere tightly to cell nuclei was reflected in the high salt concentration (0.43 M KCl) required to extract 50% of the receptors from the nuclear compartment during homogenization and in the stability of the nuclear ER population in the presence of high concentrations of a nonionic solute (urea) or increased buffer volume. Mixing and redistribution experiments showed that nuclear ER could be quantitatively and qualitatively measured in cytosolic extracts, ruling out the possibility that soluble receptors were being masked. Although Squalus oviduct ER was similar to that of testis, ER in the testis and liver of a related elasmobranch (Potamotrygon) that maintains osmotic equilibrium at 300 mosM more closely resembled mammalian ER in its elution maximum from DNA-cellulose (0.22 M NaCl) and cytosolic/nuclear ratios in low-salt buffers. We conclude that Squalus testis has a single ER pool located exclusively in the nuclear compartment. These observations support a revised concept of steroid action and further indicate that the chromatin affinity of the hormone-ER complex is an important factor in determining subfractional distribution during tissue processing. PMID:3856265

Trace elemental analysis in cancer-afflicted tissues of penis and testis by PIXE technique

Energy Technology Data Exchange (ETDEWEB)

Naga Raju, G.J. [Swami Jnanananda Laboratories for Nuclear Research, Andhra University, Visakhapatnam 530 003 (India); John Charles, M. [Swami Jnanananda Laboratories for Nuclear Research, Andhra University, Visakhapatnam 530 003 (India); Bhuloka Reddy, S. [Swami Jnanananda Laboratories for Nuclear Research, Andhra University, Visakhapatnam 530 003 (India)]. E-mail: sbr_r@yahoo.com; Sarita, P. [Swami Jnanananda Laboratories for Nuclear Research, Andhra University, Visakhapatnam 530 003 (India); Seetharami Reddy, B. [Swami Jnanananda Laboratories for Nuclear Research, Andhra University, Visakhapatnam 530 003 (India); Rama Lakshmi, P.V.B. [Pathology Department, Andhra Medical College, Visakhapatnam 530 002 (India); Vijayan, V. [Institute of Physics, Sachivalaya Marg, Bhubaneswar 751 001 (India)

2005-04-01

PIXE technique was employed to estimate the trace elemental concentrations in the biological samples of cancerous penis and testis. A 3 MeV proton beam was employed to excite the samples. From the present results it can be seen that the concentrations of Cl, Fe and Co are lower in the cancerous tissue of the penis when compared with those in normal tissue while the concentrations of Cu, Zn and As are relatively higher. The concentrations of K, Ca, Ti, Cr, Mn, Br, Sr and Pb are in agreement within standard deviations in both cancerous and normal tissues. In the cancerous tissue of testis, the concentrations of K, Cr and Cu are higher while the concentrations of Fe, Co and Zn are lower when compared to those in normal tissue of testis. The concentrations of Cl, Ca, Ti and Mn are in agreement in both cancerous and normal tissues of testis. The higher levels of Cu lead to the development of tumor. Our results also support the underlying hypothesis of an anticopper, antiangiogenic approach to cancer therapy. The Cu/Zn ratios of both penis and testis were higher in cancer tissues compared to that of normal.

Origins of the Salado, Seven Rivers, and San Andres salt margins in Texas and New Mexico: Revision 1: Topical report

International Nuclear Information System (INIS)

Boyd, S.D.; Murphy, P.J.

1987-02-01

The present boundaries of the San Andres, Seven Rivers, and Salado salts generally lie along the periphery of the Palo Duro and Tucumcari Basins. Various geologic mechanisms occurring singularly or in combination determined the positions of the salt margins. These mechanisms include nondeposition of salt and syndepositional and postdepositional dissolution. In New Mexico, San Andres units pinch out against the Pedernal and Sierra Grande Uplifts, indicating that nondeposition established the original salt margins there. Syndepositional dissolution of exposed Upper San Andres salts occurred in response to Guadalupian upwarp of the basin margins. Triassic erosion differentially removed Permian salt-bearing formations along the uplifts. Late Tertiary dissolution is indicated by fill of north-south trending collapse valleys. In Texas, Guadalupian upwarp along the Amarillo Uplift caused pinchout of Units 2 and 3 in the Lower San Andres and influenced the deposition of subsequent salt-bearing strata. The discontinuity of Upper San Andres evaporites across the Amarillo Uplift suggests syndepositional dissolution. Along the eastern and northeastern basin margin, dissolution may have accompanied Triassic erosion of locally uplifted Upper Permian strata. Tertiary dissolution is recognized beneath anomalously thick Ogallala Formation sections that overlie collasped Permian strata. 49 refs., 31 figs., 2 tabs

Follitropin receptors in rat testis. Characterization with enzymatically 125I-labeled human follitropin.

Science.gov (United States)

Ketelslegers, J M; Catt, K J

1978-07-03

The interaction between enzymatically radioiodinated human follitropin and the follitropin receptors in testis homogenate was investigated in immature and adult rats. The 125I-labeled human follitropin exhibited high binding activity with specific binding of up to 17% in the presence of an excess of testis homogenate. Approx. 50% of the bound hormone could be eluted at pH 5, and the receptor purified tracer exhibited a 3.6-fold increase in binding activity when compared with the original tracer preparation. Quantitative analysis of equilibrium binding data was performed with corrections for the measured specific activity and maximum binding activity of the tracer hormone. The equilibrium association constants (Ka) determined 24 degrees C were not significantly different in immature and adult rat testis, and the mean value for Ka was 3.9 . 10(9) M-1. At 37 degrees C, the Ka value obtained using immature rat testis was 1.3 . 10(10) M-1. The association of 125I-labeled human follitropin with immature rat testis homogenate was time and temperature dependent. In the presence of an excess of unlabeled hormone, 30--60% of the preformed hormone . receptor complex was dissociated after 24 h incubation. A specific and sensitive radioligand-receptor assay for follitropin was developed using immature rat testis homogenate. The minimum detectable dose of purified human follitropin was 0.6 ng, and human urinary and pituitary follitropin, ovine follitropin and pregnant mare serum gonadotropin reacted in the assay with equivalent slopes. The potencies of highly purified pregnent mare serum gonadotropin and highly purified human follitropin were similar in the radioligand-receptor assay, consistent with the follitropin bioactivity of the equine gonadotropin.

Giving Voice: Narrating silence, history and memory in André Brink ...

African Journals Online (AJOL)

Giving Voice: Narrating silence, history and memory in André Brink\\'s The Other Side of Silence and Before I Forget. ... Both narrators, though, draw attention to the problems associated with this reconstructive and potentially ... Article Metrics.

Sex Cord-Gonadal Stromal Tumor of the Rete Testis

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Kamran P. Sajadi

2009-01-01

Full Text Available A 34-year-old tetraplegic patient with suppurative epididymitis was found on follow-up examination and ultrasonography to have a testicular mass. The radical orchiectomy specimen contained an undifferentiated spindled sex cord-stromal tumor arising in the rete testis. Testicular sex cord-stromal tumors are far less common than germ cell neoplasms and are usually benign. The close relationship between sex cords and ductules of the rete testis during development provides the opportunity for these uncommon tumors to arise anatomically within the rete tesis. This undifferentiated sex cord-stromal tumor, occurring in a previously unreported location, is an example of an unusual lesion mimicking an intratesticular malignant neoplasm.

Sex cord-gonadal stromal tumor of the rete testis.

Science.gov (United States)

Sajadi, Kamran P; Dalton, Rory R; Brown, James A

2009-01-01

A 34-year-old tetraplegic patient with suppurative epididymitis was found on follow-up examination and ultrasonography to have a testicular mass. The radical orchiectomy specimen contained an undifferentiated spindled sex cord-stromal tumor arising in the rete testis. Testicular sex cord-stromal tumors are far less common than germ cell neoplasms and are usually benign. The close relationship between sex cords and ductules of the rete testis during development provides the opportunity for these uncommon tumors to arise anatomically within the rete tesis. This undifferentiated sex cord-stromal tumor, occurring in a previously unreported location, is an example of an unusual lesion mimicking an intratesticular malignant neoplasm.

Effect of vitamin E supplement in diet on antioxidant ability of testis in Boer goat.

Science.gov (United States)

Hong, Zhu; Hailing, Luo; Hui, Meng; Guijie, Zhang; Leyan, Yan; Dubing, Yue

2010-01-01

The aim of this study was to evaluate the supplementation of Vitamin E in diet on the antioxidant capacity of testis in Boer goat. Twenty-four healthy, Boer male kids of similar body weight (BW) were selected at 3 months of age from the kid flock. Kids were born from does treated with simultaneous flushing and artificial insemination technology. The Boer kids were divided into four groups randomly, supplemented with 0, 80, 320 and 880 IU kid(-1)d(-1) Vitamin E, which were labeled as Groups 1, 2, 3 and 4, respectively, for 150 days (5 months). Blood samples were collected at the 15th-, 30th-, 60th-, 90th-, 120th-, and 150th-day during the experimental period, and the serums were used to determine Vitamin E content. Three Boer goats in each group were slaughtered at the age of eight months at the end of the experiment. Liver and testis were collected to test the Vitamin E content and the antioxidant capacity of testis. Results showed that the content of Vitamin E in serum, liver and testis increased with the increasing addition of Vitamin E. However, the content of Vitamin E in the serum, liver and testis, in the control, was significantly lower than in Groups 2 and 3, respectively, but there was no significant difference between the control Group and Group 4. When high levels of Vitamin E (880 IU kid(-1)d(-1)) were added, contents of Vitamin E in serum, liver and testis were decreased and compared with the controls. Adding a low level (80 IU kid(-1)d(-1)) of Vitamin E can increase activity of total anti-oxidation competence (T-AOC) and superoxide dismutase (SOD), and decrease content of nitric oxide (NO) in testis. MDA (malondialdehyde) content was decreased significantly in Group 3 (P<0.05). Supplementing a low level (80 IU kid(-1)d(-1)) and middle level (320 IU kid(-1)d(-1)) of Vitamin E decreased activity of nitric oxide syntha (NOS) in testis (P<0.05). Vitamin E can increase activity of GSH-PX (glutathione peroxidase). These results indicate that supplementing

Parts harvendas ootamatult Eesti Energia nõukogu / Andres Eilart

Index Scriptorium Estoniae

Eilart, Andres

2011-01-01

Majandus- ja kommunikatsiooniminister Juhan Parts otsustas 1. juulil päevapealt Eesti Energia nõukogu liikme kohalt tagasi kutsuda Aivar Reiviku ning Rein Kuusmiku, kes olid vastu Eesti Energia üle viie miljoni euro suurusele investeeringule Weroli rapsiõlitehase juurde rajatavasse elektri- ja küttejaama. Uuteks nõukogu liikmeteks said Andres Saame ja Toomas Tauts

Sertoli cell tumor arising in a cryptorchid testis presenting as a content of inguinal hernial sac

Directory of Open Access Journals (Sweden)

Kusuma Venkatesh

2016-01-01

Full Text Available Sertoli cell tumors (SCTs are rare tumors accounting for <1% of all testicular tumors. Here, we report a rare case of SCT in a 60-year-old man presenting as a painless swelling in the right groin since childhood. Clinically, he presented with right-sided inguinal hernia with absence of the right testis. He had normal left testis and had no gynecomastia or infertility. The specimen of hernial sac showed testis with a 1.6 cm × 1.5 cm nodular mass having gray tan-cut surface. Histopathologically, the testis showed atrophy and the nodular portion showed tumor cells arranged in tubular and microcystic pattern, with no solid pattern or necrosis. The diagnosis of SCT was confirmed with immunohistochemical staining for inhibin which showed fine granular cytoplasmic positivity. Cryptorchid testis having SCT and presenting as a content of inguinal hernia is a rare occurrence.

Eesti dokfilm sai Euroopast toetust

Index Scriptorium Estoniae

2005-01-01

Euroopa Liidu MEDIA Plus programm toetab kaht Eesti dokumentaalfilmi projekti : "Maria teatri fantoomid" (Baltic Film Production ; autor Marianna Kaat) ja "Müümise kunst" (Kuukulgur Film ; autorid Andres Maimik, Jaak Kilmi)

Biometric and Ultrasonographic Evaluation of the Testis of One-humped Camel (Camelus dromedarius

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Riaz Hussain Pasha, Anas Sarwar Qureshi*, Laeeq Akbar Lodhi1 and Huma Jamil1

2011-04-01

Full Text Available Twenty four adult clinically healthy one-humped male camels (Camelus dromedarius were examined three times (beginning, mid and end in each season (winter, spring, summer and autumn for establishing the normal ultrasonic appearance and seasonal changes in the testicular parenchyma in the natural ecology of Punjab, Pakistan. The testes of each camel were scanned by using a B-mode real time ultrasound scanner fitted with a 7.5-MHz linear-array transducer. Scrotal biometry was done with the measuring tape during all the seasons of year. The tunics of the testes appeared as hyperechoic lines surrounding the homogenous, moderately echogenic parenchyma of the testis. The mediastinum testis was visualized as hyperechoic central line and a spot, in longitudinal and transverse sections, respectively. During winter season, the parenchyma was hyperechoic and mediastinum testis was seen as thin hyperechoic line. In spring, the echogenicity of parenchyma was moderate and mediastinum appeared relatively thick central hyperechoic line. In summer and autumn, less echoic parenchyma and thick band of mediastinum was recorded. Biometric studies showed significantly (P<0.01 higher scrotal length and width of the testis during winter and spring season as compared to summer and autumn. Present study revealed that the ultrasonic structure of camel testis resembles other mammals and season has an apparent effect on the testicular size and echogenicity of the testicular parenchyma in the one-humped camel.

Väitlus tumma tekstiga : Hans Anton Schults ja Andres Saal / Katre Kikas

Index Scriptorium Estoniae

Kikas, Katre

2006-01-01

Artiklis käsitletakse H. A. Schults'i (1866-1905) 1903. a. Jakob Hurdale saadetud kirjutisi, kus ta polemiseerib oma kaasaegse Andres Saaliga arutledes "vanade eestlaste" moraali, rahvuse ja religiooni teemal

Anatomy and histology of the scrotal ligament in adults: inconsistency and variability of the gubernaculum testis.

Science.gov (United States)

Cavalie, G; Bellier, Alexandre; Marnas, G; Boisson, B; Robert, Y; Rabattu, P Y; Chaffanjon, P

2018-04-01

The anatomy of gubernaculum testis (GT) is often discussed; however, the postnatal anatomy of the GT or scrotal ligament (SL) is rarely described. Hence, we performed an anatomical and histological study to analyze histologically the structures between testis and scrotum. We performed anatomical dissections on 25 human fresh cadavers' testes. Each testis was removed with its envelopes and macroscopically analyzed. Then samples were included for histological study. Finally, they were analyzed under microscope, looking for attachments between testis, epididymis and scrotal envelopes. The absence of proximal and distal attachment was found in 56.0% of cases. Looking at the proximal attachment of the SL, the main one found is the epididymal attachment (28.0%), whereas no cases of testis attachment was found. Distally, there are more variations with scrotal attachment (12%) and cremaster attachment (12.0%). We found a significant prevalence of multiple adherences in 16.0% of cases too. Finally, in 15 cases (57.7%) an attachment is present between testis and epididymis, as it is commonly described. In the majority of cases there is no attachment of the lower pole of the testis and epididymis and these structures remain free. So it seems that the SL disappears with aging. Moreover, there is not only one kind of ligamentous attachment, but a high variability of attachments at the lower pole of the testiculo-epididymal structure. When it exists, this structure is never a real ligament and it seems more appropriate to use the term "attachments".

Laparoscopic classification of the impalpable testis: an update

African Journals Online (AJOL)

intra-abdominal testis should be treated by standard open ... laparoscopy at two tertiary centers of Pediatric surgery in Egypt ... patients, 25 (21%) had bilateral NPT, whereas the rest .... inguinal approach with transperitoneal extension should.

André Leroi-Gourhan (25 août 1911–19 février 1986)

OpenAIRE

Soulier, Philippe

2007-01-01

André Leroi-Gourhan (25th August 1911 – 19th February 1986) A short biography of André Leroi-Gourhan is here presented, beginning in 1927, at the moment of his student years, until his retirement in 1982. It rests on a systematic analysis of his publications and on his personal and professional archives, collected and studied for the first time in 2001 when the author was temporally engaged by the CNRS. Going beyond the pure biography of events, such as those already presented in numerous po...

Postsotsialismist vaatemängulinna = From Post-Socialism to the City of the Spectacle / Andres Kurg

Index Scriptorium Estoniae

Kurg, Andres, 1975-

2007-01-01

Büroo Alver Trummal Arhitektid töödest, Andres Alverist ja Tiit Trummalist. Ärihoonest Tallinnas Rävala pst. 4. Autorid: Andres Alver, Tiit Trummal, Tarmo Laht, Indrek Rünkla, Ulla Mets, Sven Koppel. Konstruktor Eido Uustalu (Eesti Projekt). Projekt 2001, valmis 2006. City Plazast Tallinnas Tartu mnt. 2. Autorid: A. Alver, T. Trummal, T. Laht, I. Rünkla, Martin Melioranski, U. Mets. Konstruktor: Tiit Masso, Pike Projekt. Sisekujundus (fuajeed, restoran): Pille Lausmäe. Projekt 2001, valmis 2004. Lõige, põhiplaan, 3 värv. välis- ja 5 sisevaadet

Testicular development and relationship between body weight, testis ...

African Journals Online (AJOL)

STORAGESEVER

2009-03-20

Mar 20, 2009 ... INTRODUCTION. A major determinant of the reproductive performance of ... testis weight as one of the indices in selecting high quality breeding ... equipment (AV and collection bottles) as described by Swierstra and Rahnfeld ...

Purification of beta-acetylglucosaminase and beta-galactosidase from ram testis.

Science.gov (United States)

Caygill, J C; Roston, C P; Jevons, F R

1966-02-01

1. The presence of beta-galactosidase (EC 3.2.1.23) in an acetic acid extract of ram testis is reported. Some properties of the crude enzyme preparation were studied. 2. The purification of beta-acetylglucosaminase (EC 3.2.1.30) and of beta-galactosidase from the ram-testis extract by ammonium sulphate precipitation and chromatography on a CM-cellulose column is described. 3. The final purifications of the separated enzymes achieved were for the beta-acetylglucosaminase 35 times and for the beta-galactosidase 99 times. 4. The possibility of using DEAE-cellulose and Sephadex G-200 to purify the enzymes was investigated.

Genome-scale analysis of positional clustering of mouse testis-specific genes

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Lee Bernett TK

2005-01-01

Full Text Available Abstract Background Genes are not randomly distributed on a chromosome as they were thought even after removal of tandem repeats. The positional clustering of co-expressed genes is known in prokaryotes and recently reported in several eukaryotic organisms such as Caenorhabditis elegans, Drosophila melanogaster, and Homo sapiens. In order to further investigate the mode of tissue-specific gene clustering in higher eukaryotes, we have performed a genome-scale analysis of positional clustering of the mouse testis-specific genes. Results Our computational analysis shows that a large proportion of testis-specific genes are clustered in groups of 2 to 5 genes in the mouse genome. The number of clusters is much higher than expected by chance even after removal of tandem repeats. Conclusion Our result suggests that testis-specific genes tend to cluster on the mouse chromosomes. This provides another piece of evidence for the hypothesis that clusters of tissue-specific genes do exist.

Vulkaner andre steder i Solsystemet

DEFF Research Database (Denmark)

Haack, Henning

2007-01-01

Jupiters måne, Io, og man regner man med at Venus og formentlig også Mars stadig er vulkansk aktive. Ved at rette blikket ud i solsystemet har vi  mulighed for at studere vulkansk aktivitet under helt anderledes betingelser end her på Jorden. Hvad sker der f.eks., hvis tyngdekraften er svagere, eller...... planetens overflade måske er gloende varm? Vulkanerne andre steder i Solsystemet overgår på mange måder dem på Jorden. Venus er den planet i solsystemet, der har flest vulkaner, Mars har de største og højeste vulkaner, asteroiden Vesta har de ældste, og Jupiters måne Io har de mest aktive vulkaner i...

Origen de la surgencia del Balneario de San Andrés (Provincia de Jaén)

OpenAIRE

Hidalgo Estévez, Mari Carmen; Rey Arrans, Javier; Redondo, L.

1997-01-01

The hydrogeological context of the San Andrés spa (province of Jaén) is analysed in this work. Piezometric data, hydrochemical analysis and groundwater quality trends are discussed for groundwater samples obtained from the main aquifer units in the region (jurassic carbonatic aquifer and miocene detrital aquifer) in order to stablish the origin of the San Andrés spring. Considering altitude, discharge rate, temperature and hydrochemical features of the spring, it seems to be related to the mi...

Un recorrido sobre el autor: su problematización en Gadamer, Jauss y Eco

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Mariana Patricia Busso

2012-06-01

Full Text Available En el presente artículo intentaremos rastrear el concepto de autor en el trabajo de Hans-Georg Gadamer, Hans Robert Jauss y Umberto Eco, pensadores clave que desde la hermenéutica y el estructuralismo han abordado la problemática tríada autor – obra – lector en la segunda mitad del siglo XX. La importancia de la puesta en diálogo de estos enfoques está dada por la vigencia de la problemática de la autoría –o de la desaparición de la misma- en un contexto donde en el pensamiento social cobra vital importancia el lugar del lenguaje como capaz de crear tanto al sujeto como a la realidad por él interpretada. Los pensadores que hemos seleccionado, en este sentido, no presentan miradas homogéneas sobre la cuestión dada sus procedencias epistemológicas diversas, aunque se encuentran en un cierto modo mancomunados por el intento de otorgar un nuevo status al autor, lector y texto en relación al funcionamiento del lenguaje.

Proceedings of the 3. Summer School Jorge Andre Swieca in Nuclear Physics

International Nuclear Information System (INIS)

Lima, C.L.; Nemes, M.C.; Wolynec, E.

1987-01-01

This book contents the lectures and seminars presented during the Jorge Andre Swieca III Summer School-Nuclear Physics 1987 which happened in February 1987 in Itaipava - Rio de Janeiro - Brazil. (A.C.A.S.) [pt

Screening for carcinoma in situ of the contralateral testis in patients with germinal testicular cancer

DEFF Research Database (Denmark)

Berthelsen, J G; Skakkebaek, N E; von der Maase, H

1982-01-01

Two hundred and fifty biopsy specimens from the contralateral testis in patients with unilateral germinal testicular cancer were analysed by light microscopy for carcinoma-in-situ changes. Changes were found in 13 (5.2%) patients. One-third of patients with an atrophic contralateral testis (volume...... of cryptorchidism or both had been screened. Since the natural course of carcinoma in situ in the contralateral testis of patients with germinal testicular cancer has not been established, the patients are being re-evaluated frequently. To date two patients with carcinoma in situ have developed a second cancer....

Ristikultuuri äratajad / Heinz Valk, Eerik Kõuts, Sirje Endre

Index Scriptorium Estoniae

Valk, Heinz, 1936-

1998-01-01

Intervjuu raamatu "Rist ja raud" autorite Heinz Valgu ja Eerik Kõutsiga meie kalmistukultuurist ja vanadest sepistest ning raamatu väljaandja Sirje Endrega; raamatu fotode autor on Tiit Veermäe, kujundaja Andres Tali

Andrés Rivera, Escritor social

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Marta Waldegaray

2006-07-01

Full Text Available La narrativa de Andrés Rivera hace de la historia el material de origen de la escritura y de su convicción política de izquierda el molde en el cual desde hace ya más de cuatro décadas su escritura adquiere forma.Acontecimiento histórico, circunstancia política, poseen en sus primeras novelas el valor de verdad política, de testimonio social. La convicción ideológica que sus libros exhiben se acompaña de una trayectoria literaria que, en su práctica inicial, fue confiada a la representación r...

Effects of a simulated microgravity model on cell structure and function in rat testis and epididymis

Science.gov (United States)

Hadley, Jill A.; Hall, Joseph C.; O'Brien, Ami; Ball, Richard

1992-01-01

The effect of simulated microgravity on the structure and function of the testis and epididymis cells was investigated in rats subjected to 7 days of tail suspension. Results of a histological examination revealed presence of disorganized seminiferous tubules and accumulation of large multinucleated cells and spermatids in the lumen of the epididymis. In addition, decreases in the content of testis protein and in testosterone levels in the testis, the interstitial fluid, and the epididymis were observed.

Os antropólogos e a religião - Resenha

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Tatiane Aparecida de Almeida

2016-12-01

Full Text Available LivroMARY, André. Os antropólogos e a religião. Trad. Lúcia Mathilde Endlich Orth. São Paulo: Ideias e Letras, 2014. ISBN 978-85-6589-369-5                       Este livro é de autoria do antropólogo francês André Mary que é também professor da EHESS, diretor de pesquisa no CNRS na França, redator-chefe  da revista Archives des Sciences Sociales des Religions desde o ano de 2005 e é autor de outros livros, por exemplo, Le Bricolage Africain des Héros Chrétiens (2000, no qual o autor demonstra seus conhecimentos acadêmicos em relação à religiosidade africana. 

“O Negro André”: a questão racial na vida e no pensamento do abolicionista André Rebouças

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Anita Maria Pequeno Soares

2017-08-01

Full Text Available The main objective of this work was to analyze how the context of racial relations influenced the construction of the self and the intellectual production of black intellectual and abolitionist André Rebouças. Through primary sources, it was possible to recreate the process of “self construction” lived by André Rebouças as a black man who had African ancestry. It was possible to notice that some characteristics of his social thought became radical at the same time the self-recognition of his racial condition became deeper, during the period in which he was self-exiled from Brazil, immediately after the proclamation of the republic in 1889. During his life in Africa, he broke his silence about his racial reality. In this period, the construction of his self goes through a transformation, as he begins to see himself and to reaffirm himself as a black and African man. This awaken to “racial consciousness” was interpreted, like Mattos suggested (2010, inspired by the concept of “double consciousness”, elaborated by Du Bois and further developed by Paul Gilroy in “The Black Atlantic” (2012.

Transcriptome profiling of testis during sexual maturation stages in Eriocheir sinensis using Illumina sequencing.

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Lin He

Full Text Available The testis is a highly specialized tissue that plays dual roles in ensuring fertility by producing spermatozoa and hormones. Spermatogenesis is a complex process, resulting in the production of mature sperm from primordial germ cells. Significant structural and biochemical changes take place in the seminiferous epithelium of the adult testis during spermatogenesis. The gene expression pattern of testis in Chinese mitten crab (Eriocheir sinensis has not been extensively studied, and limited genetic research has been performed on this species. The advent of high-throughput sequencing technologies enables the generation of genomic resources within a short period of time and at minimal cost. In the present study, we performed de novo transcriptome sequencing to produce a comprehensive transcript dataset for testis of E. sinensis. In two runs, we produced 25,698,778 sequencing reads corresponding with 2.31 Gb total nucleotides. These reads were assembled into 342,753 contigs or 141,861 scaffold sequences, which identified 96,311 unigenes. Based on similarity searches with known proteins, 39,995 unigenes were annotated based on having a Blast hit in the non-redundant database or ESTscan results with a cut-off E-value above 10(-5. This is the first report of a mitten crab transcriptome using high-throughput sequencing technology, and all these testes transcripts can help us understand the molecular mechanisms involved in spermatogenesis and testis maturation.

[Epidermoid cyst of the testis difficult to make a preoperative diagnosis on the echoic examination: a case report].

Science.gov (United States)

Yamamoto, Keisuke; Takada, Tsuyoshi; Momohara, Chikahiro; Komori, Kazuhiko; Honda, Masahito; Fujioka, Hideki

2003-04-01

A case of epidermoid cyst of the testis is presented. The patient was a 64-year-old man who complained of a painless mass in the left scrotum. Physical examination revealed a hen-egg sized enlargement of the left scrotal contents. The ultrasonographic appearance did not show a hyperechoic partition, which is called echogenic rim, a characteristic of this tumor on the echoic examination, and was homogeneous, almost similar to that of a normal testis. Because malignant testicular tumors could not be excluded preoperatively, excisional biopsy of the left testis was performed first. Histological diagnosis was an epidermoid cyst of the testis. As the left testis was almost completely occupied by the tumor and no normal testicular tissue was recognized, we performed orchiectomy additionally. Epidermoid cyst of the testis is a rare benign tumor that accounts for about 1 percent of all testicular tumors. It clinically resembles malignant testicular tumors, and orchiectomy is often performed for treatment. About 154 cases of testicular epidermoid cyst have been reported in the Japanese literature and are reviewed briefly here.

Globaliseerumine : oht või võimalus? / Andres Arrak

Index Scriptorium Estoniae

Arrak, Andres, 1958-2017

2007-01-01

Globaliseerumise ja võrgustumise muutumine võimaluseks või ohuks sõltub konkreetse riigi majanduse ja tööturu kohanemisvõimest. Globaalsete finantsvoogude kirjeldus, kapitali ja Eestisse tulevate rahavoogude analüüs ning hinnang Eesti tööturu paindlikkusele ja ettevõtjate innovatiivsusele. Graafikud: Otse- ja portfelliinvesteeringute ning laenude sissevool Eestisse 1992-2006; Diagramm: Eesti tööjõuturg sammub Ameerika jälgedes. Vt. samas: Andres Saarniit. Raha ei ole kuhugi kadunud

Eramu Viimsis = Private residence in Viimsi

Index Scriptorium Estoniae

2011-01-01

Arhitektide Toomas Tammise ja Kaiko Kivi (Arhitektuuriagentuur) poolt kunstikollektsionäärile projekteeritud eramu sisekujundusest. Sisearhitektid Andres Labi ja Janno Roos (Ruumilabor OÜ). Peegliraamide autor Anne Daniela Rodgers. Loetletud sisearhitektide koos tehtud töid

Study on the abnormalities in sperm and gene mutation induced by retention of 147Pm in testis

International Nuclear Information System (INIS)

Zhu Shoupeng; Lun Mingyue; Yang Shuqin

1990-05-01

The purpose of the present study is to ascertain 147 Pm retention in testis and its radiogenotoxicological effects of gene mutation through varying radioactivities of internal exposure. Especially the accumulation of 147 Pm in testis induces the dominant lethal, dominant skeletal mutation and abnormalities in sperm. Studies indicated that the cumulative absorption dose in testis increases as the internal exposure of 147 Pm increases. The internal exposure of 147 Pm can destroy the genetic materials and raise the rates of dominant lethal and dominant mutation of skeletal abnormalities in the offspring. The relationship between the rate of dominant skeletal mutation (B) and accumulated radioactivities of 147 Pm (D) in testis can be described by a linear equation that is B 20.68 + 35.48 D. The relationship between abnormalities of the sperm and the cumulative dose from 147 Pm in testis can be expressed by the following equation: S = 10.8705 D 0.5224 + 3.1768

Purification of β-acetylglucosaminase and β-galactosidase from ram testis

Science.gov (United States)

Caygill, J. C.; Roston, Christine P. J.; Jevons, F. R.

1966-01-01

1. The presence of β-galactosidase (EC 3.2.1.23) in an acetic acid extract of ram testis is reported. Some properties of the crude enzyme preparation were studied. 2. The purification of β-acetylglucosaminase (EC 3.2.1.30) and of β-galactosidase from the ram-testis extract by ammonium sulphate precipitation and chromatography on a CM-cellulose column is described. 3. The final purifications of the separated enzymes achieved were for the β-acetylglucosaminase 35 times and for the β-galactosidase 99 times. 4. The possibility of using DEAE-cellulose and Sephadex G-200 to purify the enzymes was investigated. PMID:5949569

Transcriptome analysis of spermatogenically regressed, recrudescent and active phase testis of seasonally breeding wall lizards Hemidactylus flaviviridis.

Directory of Open Access Journals (Sweden)

Mukesh Gautam

Full Text Available Reptiles are phylogenically important group of organisms as mammals have evolved from them. Wall lizard testis exhibits clearly distinct morphology during various phases of a reproductive cycle making them an interesting model to study regulation of spermatogenesis. Studies on reptile spermatogenesis are negligible hence this study will prove to be an important resource.Histological analyses show complete regression of seminiferous tubules during regressed phase with retracted Sertoli cells and spermatognia. In the recrudescent phase, regressed testis regain cellular activity showing presence of normal Sertoli cells and developing germ cells. In the active phase, testis reaches up to its maximum size with enlarged seminiferous tubules and presence of sperm in seminiferous lumen. Total RNA extracted from whole testis of regressed, recrudescent and active phase of wall lizard was hybridized on Mouse Whole Genome 8×60 K format gene chip. Microarray data from regressed phase was deemed as control group. Microarray data were validated by assessing the expression of some selected genes using Quantitative Real-Time PCR. The genes prominently expressed in recrudescent and active phase testis are cytoskeleton organization GO 0005856, cell growth GO 0045927, GTpase regulator activity GO: 0030695, transcription GO: 0006352, apoptosis GO: 0006915 and many other biological processes. The genes showing higher expression in regressed phase belonged to functional categories such as negative regulation of macromolecule metabolic process GO: 0010605, negative regulation of gene expression GO: 0010629 and maintenance of stem cell niche GO: 0045165.This is the first exploratory study profiling transcriptome of three drastically different conditions of any reptilian testis. The genes expressed in the testis during regressed, recrudescent and active phase of reproductive cycle are in concordance with the testis morphology during these phases. This study will pave

The genusGuenthera Andr. in Bess. (Brassicaceae, Brassiceae

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Gómez-Campo, César

2003-12-01

Full Text Available A group of nine species -now included in Brassica— differ from all the other species in several characters, mainly in the stylar portion of their pistils always without seed primordia. Also in their branched subterranean stem (caudex with several leaf rosettes, their leaves entire to deeply pinnatifid but never pinnatisect, their shallowly notched cotyledons and their flattened, elliptic or ovoid seed contour. It is suggested to include these species under the generic denomination Guenthera Andr, in Bess. New ñames for the species and subspecies are provided, as well as a determination key for the species.Un grupo de nueve especies actualmente incluidas en Brassica difiere de todas las demás por varios caracteres, sobre todo por la porción estilar de sus pistilos, que siempre carece de primordios seminales. Además, por su tallo subterráneo ramificado, que forma un cáudex con varias rosetas; sus hojas de enteras hasta profundamente pinnatífidas, pero nunca pinnatisectas; sus cotiledones solo muy ligeramente escotados, y sus semillas, que tienden a ser elipsoidales o aplanadas. Se propone agruparlas todas bajo la denominación genérica Guenthera Andr, in Bess. Se detallan los nuevos nombres para las especies y Subespecies y se añade una clave para diferenciar las especies.

Estudio de la frecuencia de hemoglobinopatías en las islas de San Andrés y Providencia, Colombia

Directory of Open Access Journals (Sweden)

María del Pilar Bernal

1995-03-01

Full Text Available Se realizó un estudio destinado a determinar la frecuencia de hemoglobinopatías en las islas caribeñas de San Andrés y Providencia, en 544 individos individuos: 443 de San Andrés y 101 de Providencia. La frecuencia en San Andrés fue del 12,8% y en Providencia 20,8%; las hemoglobinopatías más frecuentes fueron: el rasgo falciforme, la hemoglobina C y la beta-talasemia. Los datos indican, que las hemoglobinopatías en esta región del país como problema de salud pública, tienen importancia y nos dan información sobre el origen geográfico de la población.

Comparative morphophysiological evaluation of the testis of adult ...

African Journals Online (AJOL)

olayemitoyin

Wistar rats fed low protein-energy diet and dosed with aqueous extracts ... extracts of C. australis seed and stem, 300mg/kg body weight/day for seven days, on the testis of the adult Wistar rat ..... Modern Study of Traditional Chinese Medicine,.

Book Review: America’s Blind Spot: Chávez, Oil and US Security by Andrés Cala and Michael Economides

DEFF Research Database (Denmark)

Boscan, Luis

2014-01-01

Review of: America’s Blind Spot: Chávez, Oil and US Security. Andrés Cala and Michael Economides. Continuum Books. 2012.......Review of: America’s Blind Spot: Chávez, Oil and US Security. Andrés Cala and Michael Economides. Continuum Books. 2012....

Sisearhitektuuri uudised / Aino Ingrid Sepp, Aale Kask

Index Scriptorium Estoniae

Sepp, Aino Ingrid

2007-01-01

Tallinnas lillesalongi Masha sisekujunduse autorid on Ahti Lyra ja Kristiine Lõuk. Pärnu ööklubi Str sisekujunduse autor on Hannes Praks. Tallinna Viru keskuse avatud baari sisekujunduse autorid on Kärt Villmann ja Andres Rohtla

La piratería de derechos de autor y el desarrollo: evidencia de los Estados Unidos en el siglo XIX

Directory of Open Access Journals (Sweden)

Zorina Khan

2008-06-01

Full Text Available ¿La falta de derechos internacionales de autor beneficia o perjudica a los países en desarrollo? Este artículo examina los efectos de la piratería de derechos de autor en Estados Unidos durante un período cuando era un país en desarrollo. Las leyes estadounidenses protegían los derechos de autor de sus ciudadanos desde 1790, pero hasta 1891 consideraron que las obras de los ciudadanos extranjeros eran de dominio público. En 1891 se modificaron para que los extranjeros obtuvieran protección de derechos de autor si satisfacían ciertas condiciones. Este episodio de la historia estadounidense es útil para investigar las consecuencias de la piratería de derechos internacionales de autor. El análisis usa registros de derechos de autor, información de los autores, títulos y precios de los libros, datos financieros de los balances de una compañía editorial muy importante y demandas judiciales sobre cuestiones de derechos de autor para investigar los efectos de bienestar de la violación de las obras extranjeras sobre los editores, los autores y el público estadounidense. Los resultados indican que Estados Unidos se benefició con la piratería y que la elección del régimen de derechos de autor fue endógena al nivel de desarrollo económico.

Teresa Andrés y la organización Cultura Popular: una propuesta de coordinación bibliotecaria (1936-1938

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Seguí i Francés, Romà

2011-12-01

Full Text Available Teresa Andrés Zamora es conocida por su actividad al frente de la Sección de Bibliotecas de Cultura Popular. Este trabajo describe las relaciones que se establecieron entre Teresa Andrés y Cultura Popular, tras hacerse cargo de las responsabilidades del Ministerio de Instrucción Pública.

Revolver, kala ja harmoonia / Andres Tolts ; intervjueerinud Kadri Karro

Index Scriptorium Estoniae

Tolts, Andres, 1949-2014

2009-01-01

Andres Toltsi juubelinäitused Tallinnas: "Näitus" Tallinna Kunstihoones 25.9-25.10, "Asjad" Hobusepea galeriis 30.9-12.10, "Juubelinäitus" Haus galeriis 8.10-13.11. Kunstnik räägib oma loomingust, revolvri ja kala motiivist oma töödes, mõttekaaslusest, eestiaegsest maailmavaatest, harmooniast ja isikupärast kunstis ning elus, ilust ja inetusest, kaasaja kunstnike vajadusest oma loomingut sõnade abil seletada

O DESAPARECIMENTO DO AUTOR NAS TRAMAS DA LITERATURA DIGITAL: UMA REFLEXÃO FOUCAULTIANA

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Edgar Roberto Kirchof

2009-08-01

Full Text Available O presente artigo aborda a questão da autoria na literatura digital sob a perspectiva do filósofo francês Michel Foucault. Inicialmente, apresenta-se o estado recente da discussão a partir de duas posições antagônicas: o desaparecimento do autor na estrutura hipertextual, de um lado, e o fortalecimento de sua soberania, de outro lado. Após uma breve sistematização do que tem sido considerado literatura digital pela crítica contemporânea, apresenta-se uma síntese da noção foucaultiana sobre o problema da autoria, a partir da qual passa-se à argumentação, inspirada no pensamento de Foucault, segundo a qual o autor do hipertexto não desaparece enquanto indivíduo responsável por um novo tipo de escrita, mas sua identidade passa por alguns deslocamentos discursivos significativos enquanto função-autor.

Läänemere strateegia arvestab kodanike ettepanekutega / Jose Palma Andres ; interv. Erkki Bahovski

Index Scriptorium Estoniae

Palma Andres, Jose

2008-01-01

Euroopa Komisjoni regionaalpoliitika peadirektoraadi direktor Jose Palma Andres vastab küsimustele, mis puudutavad avalikku debatti Läänemere strateegia üle ning Venemaa partnerlust Läänemere strateegias. Lisa: [Läänemere strateegia

Viimsi keskuse muutumised ajas = Alterations of the Viimsi Centre in Time / Triin Ojari

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Ojari, Triin, 1974-

2002-01-01

Viimsi keskusesse on hooneid projekteerinud arhitektid Rein Veber, Ado Eigi, Rein Hansberg, Andres Alver, planeeringu autor on Rein Veber. 2002. a. valmis soomlase Matti Anttila büroo Architecture Workshop 2 koostatud üldplaneeringu ideeprojekt. 1 ill

Vigencia de la filosofía de Kant en dos expresiones actuales de la inteligencia filosófica en América Latina: Arturo Andrés Roig y Franz J. Hinkelammert The Force of Kant's Philosophy in Two Present Expressions of the Philosophical Intelligence in Latin America: Arturo Andrés Roig y Franz J. Hinkelammert

Directory of Open Access Journals (Sweden)

Yamandú Acosta

2006-12-01

Full Text Available Al cumplirse doscientos años de la muerte de Immanuel Kant 2004, considerar la vigencia de su pensamiento filosófico, se constituyó en un imperativo categórico, para quienes nos inscribimos en la tradición de la filosofía occidental. En cumplimiento del mismo, el texto que se presenta se ocupa de la vigencia de la filosofía del filósofo de Königsberg a través de la consideración de dos expresiones de la inteligencia filosófica en América Latina: Arturo Andrés Roig (Mendoza, Argentina, 1922 y Franz J. Hinkelammert (Emsdetten, Alemania,1931. Los programas de investigación en curso de los dos autores elegidos, en el abordaje y desarrollo de distintos tópicos, proceden argumentativamente desde, contra y más allá de Kant, exhibiendo una singular vigencia de su filosofía al interior de los mismos. En el pensamiento de Arturo Andrés Roig, los tópicos de referencia que se consideran son: la normatividad del pensamiento filosófico, la filosofía de la historia, la fundamentación de una moral emergente y la fundamentación de una estética motivacional. De la producción teórica de Franz J. Hinkelammert, se presentan: la crítica a la razón utópica y el realismo político, la crítica trascendental de los marcos categoriales de los pensamientos sociales, la trascendentalidad del sujeto y el problema del universalismo ético en la tensión entre la ética de la responsabilidad y la ética de principios. Surge de la consideración de los asuntos enumerados, que en relación al universalismo abstracto de Kant, estos dos exponentes de la inteligencia filosófica en América Latina, convergen en la fundamentación de un universalismo concreto.Currency of Kant's philosophy in two recent expressions of the philosophical intelligence in Latin America: Arturo Andrés Roig and Franz J. Hinkelammert. When it is twohundred years of Immanuel Kant´s death (2004, to consider the currency of his philosophical thought means a categorial must

Gene expression profiles in testis of pigs with extreme high and low levels of androstenone

DEFF Research Database (Denmark)

Moe, Maren; Meuwissen, Theo; Lien, Sigbjørn

2007-01-01

Boar taint is a major obstacle when using uncastrated male pigs for swine production. One of the main compounds causing this taint is androstenone, a pheromone produced in porcine testis. Here we use microarrays to study the expression of thousands of genes simultaneously in testis of high and low...

"Riigikogu hoone 90" = "Estonian parliament building 90" / Janno Roos, Andres Labi

Index Scriptorium Estoniae

Roos, Janno, 1976-

2013-01-01

Eesti Sisearhitektide Liidu 2012. aasta näituse kujunduse preemia pälvinud näitusest (Lossiplats 1A). Kujunduse autorid Janno Roos ja Andres Labi (Ruumilabor). Kuraator Mait Väljas. Graafiline disain: Identity. Sisearhitekti ja ESLi aastapreemiate žürii liikme Mari Kurismaa ning arhitektuuriajaloolase Leele Välja arvamused

SUTD-i koorik = SUTD Gridshell / Andres Sevtšuk, Raul Kalvo

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Sevtšuk, Andres, 1981-

2013-01-01

Singapuri Tehnoloogia ja Disaini Ülikooli (SUTD) raamatukogu paviljon. Eskiis valmis esimese aasta üliõpilastele korraldatud töötoas. Algse ideega töötas edasi City Form Lab (arhitektid Andres Sevtšuk, Raul Kalvo). Paviljon pandi kokku ligi saja üliõpilase osalusel. Valmis: mai 2013

Baltoscandal on lõppenud, uued mõtted on saadud / Andres Keil

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Keil, Andres, 1974-

2006-01-01

Eesti teater oli Baltoscandalil koondatud olematu teatri mõiste alla. Andres Noormetsa "Reunioon", Mart Kangro ja Ansambel U "Mäng", Marco Laimre "Vangistus", Asko Künnapi "Säälpool jõge", Anders Härmi "Cooking and Shitting", Sven Kuntu "Miks Eesti mehed ei tantsi?", Linnar Priimäe "Inimese lõhn"

Identification of Hedgehog signaling outcomes in mouse testis development using a hanging drop-culture system.

Science.gov (United States)

Szczepny, Anette; Hogarth, Cathryn A; Young, Julia; Loveland, Kate L

2009-02-01

The Hedgehog (Hh) signaling pathway affects fetal testis growth. Recently, we described the dynamic cellular production of Hh signaling pathway components in juvenile and adult rodent testes. The Hh signaling is understood to regulate cord formation in the fetal testis, but minimal knowledge exists regarding how Hh signaling impacts the postnatal testis. To investigate this, we employed hanging drop cultures, which are used routinely in embryoid body formation. This approach has the advantage of using small media volume, and we examined its suitability for short-term culture of both murine embryonic gonads and adult testis tubules. The effects of cyclopamine, a specific Hh signaling inhibitor, were examined following culture of Embryonic Day 11.5 urogenital ridges (as control) and adult seminiferous tubule fragments for 24-48 h using histological, cell proliferation, and gene expression analyses. Cultured embryonic testes displayed generally normal cord structure, anti-Müllerian hormone (Amh) expression, and cell proliferation; known Hh target gene expression (Gli1, osteopontin, official symbol Spp1, and Amh) was altered in response to cyclopamine. Cultured adult tubules exhibited some loss of seminiferous epithelium organization over 48 h. Spermatogonia continued to proliferate, however, and no significant loss of viability was noted overall. Addition of cyclopamine significantly affected levels of Gli1, Igfbp6, Ccnd2 (cyclin D2), Ccnb1 (cyclin B1), Spp1, Kit, and Amh mRNAs; these genes have been shown previously to be expressed in Sertoli and germ cells. These novel results identify Hh target genes in the testis and demonstrate this signaling pathway likely affects cell survival and differentiation in the context of normal adult testis.

Jacobsens ukendte samling af stensager fra den græske oldtid. Obsidian, økser, matricer, ansigtssten og andre sjældne oldsager

DEFF Research Database (Denmark)

Sørensen, Lasse

2012-01-01

Jacobsens ukendte samling af stensager fra den græske oldtid. Obsidian, økser, matricer, ansigtssten og andre sjældne oldsager......Jacobsens ukendte samling af stensager fra den græske oldtid. Obsidian, økser, matricer, ansigtssten og andre sjældne oldsager...

Aspectos Contábeis dos Créditos de Carbono: Estudo com Autores Nacionais

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Vanderlei dos Santos

2013-12-01

Full Text Available O estudo objetiva verificar o entendimento de autores nacionais no que concerne à classificação, forma de reconhecimento e mensuração das operações com créditos de carbono. O estudo de natureza descritiva foi realizado em 2011, por meio de pesquisa de levantamento ou survey, com abordagem quantitativa. Utilizou-se o questionário como instrumento de coleta de dados, que foi enviado a 23 pesquisadores nacionais que possuem publicação de artigos relacionados à contabilização dos créditos de carbono em periódicos nacionais. Obtiveram-se nove respostas, que constituíram numa amostra por acessibilidade. Para a análise dos dados obtidos optou-se pelo uso da técnica da entropia informacional. Os resultados do estudo mostraram que, quanto à classificação dos créditos de carbono, há um entendimento maior entre os autores de que se trata de ativos especiais e que não podem ser considerados como commodity. Observou-se que não há consenso entre os autores em classificar os créditos de carbono como ativo intangível ou estoque. Deste modo, concluiu-se que ainda existem divergências no entendimento dos autores analisados no que concerne aos aspectos contábeis das operações com créditos de carbono. O artigo contribui principalmente na medida em que busca consolidar diferentes opiniões de autores, que pesquisam sobre a temática, demonstrando aspectos convergentes e divergentes, além de enfatizar lacunas para desenvolver pesquisas futuras.

Study on the abnormalities in sperm and gene mutation induced by retention of {sup 147}Pm in testis

Energy Technology Data Exchange (ETDEWEB)

Shoupeng, Zhu; Mingyue, Lun; Shuqin, Yang [Suzhou Medical Coll., JS (China)

1990-05-01

The purpose of the present study is to ascertain {sup 147}Pm retention in testis and its radiogenotoxicological effects of gene mutation through varying radioactivities of internal exposure. Especially the accumulation of {sup 147}Pm in testis induces the dominant lethal, dominant skeletal mutation and abnormalities in sperm. Studies indicated that the cumulative absorption dose in testis increases as the internal exposure of {sup 147}Pm increases. The internal exposure of {sup 147}Pm can destroy the genetic materials and raise the rates of dominant lethal and dominant mutation of skeletal abnormalities in the offspring. The relationship between the rate of dominant skeletal mutation (B) and accumulated radioactivities of {sup 147}Pm (D) in testis can be described by a linear equation that is B 20.68 + 35.48 D. The relationship between abnormalities of the sperm and the cumulative dose from {sup 147}Pm in testis can be expressed by the following equation: S = 10.8705 D{sup 0.5224} + 3.1768.

San Andrés: Cotidianidad turística vs. idealismo desarrollista

Directory of Open Access Journals (Sweden)

José Ernesto Ramírez

1988-01-01

Full Text Available Pragmatic adaptation and idealistic intervention: An analytical description of development agencies within a context of political clientelism in San Andrés Island Colombia. (Tesis de doctorado en desarrollo. University Madison Wisconsin, 1980 Michael Jack Rosherg. University Microfilm Intemational. Ann Arbor, 1982, 301 págs. 6 ils. 40 cuadros.

Ajaloo ja kaasaja süntees Rebala muinasmaastikul / Ell-Maaja Randküla

Index Scriptorium Estoniae

Randküla, Ell-Maaja, 1939-2016

2006-01-01

Arhitekt Andres Siimu projekteeritud Estonian Golf Countri Club'i Jägala golfiklubi (Mannila küla, Jõelähtme) sisekujundus. Sisearhitekt Juta Lember, kes projekteeris ka tammepuust mööbli. Ehitus: AS Restor. Nõupidamisruumi toolide ja nagide autor on Toivo Raidmets, metallvalgustite autor Tarmo Luisk. A. Siimu ja J. Lemberi tööd on hinnatud Eesti Kultuurkapitali aastapreemiaga. Ill.: 3 korruste plaani, värv. välisvaade, 22 sisevaadet

Noblessneri Loomemaja = Noblessner Creative house / Rasmus Tamme, Jaanus Saarepera, Eero Jürgenson, Andres Jomp

Index Scriptorium Estoniae

2015-01-01

Noblessneri Loomemaja Tallinnas Tööstuse 48/Peetri 11, valminud 2014. Arhitektid Rasmus Tamme, Jaanus Saarepera (ARS Projekt), sisearhitektid Eero Jürgenson, Andres Jomp (ARS Projekt). 2014. aasta Kultuurkapitali Arhitektuuripreemia kandidaat

EL DERECHO DE AUTOR EN COLOMBIA DESDE UNA PERSPECTIVA HUMANISTA

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Ramiro Rodríguez López

2012-01-01

Full Text Available Se considera que el Pacto Internacional de Derechos Económicos, Sociales y Culturales, promulgado por las Naciones Unidas en 1966, determinó la necesidad de garantizar a las personas el derecho a beneficiarse tanto de los intereses morales como de los materiales sobre las creaciones del intelecto, denominadas propiedad intelectual. Al respecto, se considera posible plantear su estudio desde una perspectiva humanista, iniciando el análisis desde la precisión de derechos de autor. Para ello, se estudia su consagración normativa en las constituciones políticas de 1886 y 1991; la importancia de los instrumentos internacionales a los cuales ha adherido el Estado colombiano y su desarrollo en la jurisprudencia nacional, donde se ha hecho una clara referencia del derecho de autor como un derecho contenido en el artículo 27 de la Declaración Universal de los Derechos Humanos de 1948.

Abjeção em textos de André Sant’Anna

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Leandro Salgueirinho

2009-07-01

Full Text Available Trata-se de uma leitura de textos do escritor André Sant’Anna a partir da problematização que, em The Return of the Real (1986, o crítico de arte norte-americano Hal Foster faz da noção de abjeto e da dita abject art.

Andres Ehin tähistas sünnipäeva raamatuesitlusega / Maire Kõrver

Index Scriptorium Estoniae

Kõrver, Maire, 1961-

2006-01-01

Andres Ehin esitles oma luulekogu "Põdrapõrnikapääsukene" ja selle ingliskeelset tõlget "Moose Beetle Swallow" oma sünnipäeval Iiri suursaadiku residentsis, kus oli kohal ka luulekogu tõlkija, Iiri luuletaja Patrick Cotter

Study on changes of sperm count and testis tissue in black mouse after neutron irradiation

Energy Technology Data Exchange (ETDEWEB)

Chun, Ki Jung; Seo, Won Sook [KAERI, Daejeon (Korea, Republic of); Son, Hwa Young [Chungnam National Univ., Daejeon (Korea, Republic of)

2006-03-15

For the purpose of the biological effect in black mouse by neutron irradiation, mice were irradiated with 16 or 32 Gy neutron (flux: 1.036739E+09) by lying flat pose at BNCT facility on HANARO Reactors. And 90 days later of irradiation, physical changes of testis and testis tissue were examined. There were no weight changes but a little bit volume changes and sperm counts in the tests. Atrophy of seminiferous tubules irradiated with 32 Gy neutron is increased in number and severity and those in stage VI showed depletion of spermatogonia and pachytene spermatocytes compared to the non-irradiated control group. Testis damage of black mouse was not recovered after long time by 32 Gy neutron irradiation.

Study on changes of sperm count and testis tissue in black mouse after neutron irradiation

International Nuclear Information System (INIS)

Chun, Ki Jung; Seo, Won Sook; Son, Hwa Young

2006-01-01

For the purpose of the biological effect in black mouse by neutron irradiation, mice were irradiated with 16 or 32 Gy neutron (flux: 1.036739E+09) by lying flat pose at BNCT facility on HANARO Reactors. And 90 days later of irradiation, physical changes of testis and testis tissue were examined. There were no weight changes but a little bit volume changes and sperm counts in the tests. Atrophy of seminiferous tubules irradiated with 32 Gy neutron is increased in number and severity and those in stage VI showed depletion of spermatogonia and pachytene spermatocytes compared to the non-irradiated control group. Testis damage of black mouse was not recovered after long time by 32 Gy neutron irradiation

Molecular cloning of a novel nuclear factor, TDRP1, in spermatogenic cells of testis and its relationship with spermatogenesis

Energy Technology Data Exchange (ETDEWEB)

Wang, Xuanchun [Department of Endocrinology, Huashan Hospital, Institute of Endocrinology and Diabetology at Fudan University, Shanghai Medical College, Fudan University, Shanghai 200040 (China); Jiang, Haowen [Department of Urology, Huashan Hospital, Institute of Urology at Fudan University, Shanghai Medical College, Fudan University, Shanghai 200040 (China); Zhou, Wenbai; Zhang, Zhaoyun; Yang, Zhihong [Department of Endocrinology, Huashan Hospital, Institute of Endocrinology and Diabetology at Fudan University, Shanghai Medical College, Fudan University, Shanghai 200040 (China); Lu, Yong [Department of Urology, Huashan Hospital, Institute of Urology at Fudan University, Shanghai Medical College, Fudan University, Shanghai 200040 (China); Lu, Bin [Department of Endocrinology, Huashan Hospital, Institute of Endocrinology and Diabetology at Fudan University, Shanghai Medical College, Fudan University, Shanghai 200040 (China); Wang, Xiang [Department of Urology, Huashan Hospital, Institute of Urology at Fudan University, Shanghai Medical College, Fudan University, Shanghai 200040 (China); Ding, Qiang, E-mail: dingqiangd@hotmail.com [Department of Urology, Huashan Hospital, Institute of Urology at Fudan University, Shanghai Medical College, Fudan University, Shanghai 200040 (China); Hu, Renming, E-mail: renminghu@fudan.edu.cn [Department of Endocrinology, Huashan Hospital, Institute of Endocrinology and Diabetology at Fudan University, Shanghai Medical College, Fudan University, Shanghai 200040 (China)

2010-03-26

We reported the identification of a novel gene termed TDRP (encoding testis development-related protein) that might be involved in spermatogenesis. The human TDRP gene had two distinct transcripts, TDRP1 and TDRP2, which encoded proteins of 183 aa and 198 aa respectively. Tdrp mRNA was predominantly expressed in testis tissue. We generated rabbit polyclonal antibodies specific against human TDRP1. Immunohistochemistry analysis showed TDRP1 was expressed in spermatogenic cells, especially with high expression in spermatocytes. We provided evidence that TDRP1 distributed in both cytoplasm and nuclei of spermatogenic cells. Expression patterns of Tdrp1 mRNA and its protein were investigated in the rat testis tissues of different developmental stages. Both Tdrp1 mRNA and its protein were barely detected in the testis of neonatal rats, increased remarkably at 3 weeks postpartum, and peaked at 2 months postpartum. We also investigated TDRP1 expressions in testis tissues of azoospermic men with defective spermatogenesis. Western blot analysis showed that TDRP1 expressions were significantly lower in the testis tissues of azoospermic men compared with normal controls. These current data demonstrated that as a nuclear factor, TDRP1 might play an important role in spermatogenesis.

Molecular cloning of a novel nuclear factor, TDRP1, in spermatogenic cells of testis and its relationship with spermatogenesis

International Nuclear Information System (INIS)

Wang, Xuanchun; Jiang, Haowen; Zhou, Wenbai; Zhang, Zhaoyun; Yang, Zhihong; Lu, Yong; Lu, Bin; Wang, Xiang; Ding, Qiang; Hu, Renming

2010-01-01

We reported the identification of a novel gene termed TDRP (encoding testis development-related protein) that might be involved in spermatogenesis. The human TDRP gene had two distinct transcripts, TDRP1 and TDRP2, which encoded proteins of 183 aa and 198 aa respectively. Tdrp mRNA was predominantly expressed in testis tissue. We generated rabbit polyclonal antibodies specific against human TDRP1. Immunohistochemistry analysis showed TDRP1 was expressed in spermatogenic cells, especially with high expression in spermatocytes. We provided evidence that TDRP1 distributed in both cytoplasm and nuclei of spermatogenic cells. Expression patterns of Tdrp1 mRNA and its protein were investigated in the rat testis tissues of different developmental stages. Both Tdrp1 mRNA and its protein were barely detected in the testis of neonatal rats, increased remarkably at 3 weeks postpartum, and peaked at 2 months postpartum. We also investigated TDRP1 expressions in testis tissues of azoospermic men with defective spermatogenesis. Western blot analysis showed that TDRP1 expressions were significantly lower in the testis tissues of azoospermic men compared with normal controls. These current data demonstrated that as a nuclear factor, TDRP1 might play an important role in spermatogenesis.

Dibujos que hablan : El ilustrador como autor

OpenAIRE

Isol

2011-01-01

El dibujante en el libro ilustrado tiene el mismo poder que el director en el teatro. Elige el escenario, los personajes, la mirada que va a tener sobre ese "cuento” que se cuenta. Por eso el ilustrador es también un autor, y sus elecciones crean sentido narrativo. Esto que es tan usual en teatro y cine, todavía es difícil de asumir para algunos ilustradores y editores: el valor de la imagen en los libros, y su poder narrativo. De hecho, hace diez años en Argentina, el ilustrador no cobraba d...

Tallinna idee / Andres Alver, Ott Alver, Marten Kaevats ; intervjueerinud Margit Mutso ; kommenteerinud Douglas Gordon

Index Scriptorium Estoniae

Alver, Andres, 1953-

2011-01-01

17. veebruaril esitleti raamatut "Tallinna idee", mis on koostatud Eesti Kunstiakadeemia 4. kursuse arhitektuuritudengite kursuseprojektide põhjal. Tallinna teemal vestlevad tudengid Ott Alver ja Marten Kaevats ning nende juhendaja professor Andres Alver

Imaging of mesothelioma of tunica vaginalis testis

Energy Technology Data Exchange (ETDEWEB)

Bertolotto, M. [University of Trieste, Department of Radiology, Trieste (Italy); Boulay-Coletta, I. [Fondation Hopital Saint Joseph, Service d' Imagerie Medical, Paris (France); Butini, R. [Ospedale S. Giacomo, Department of Radiology, Castelfranco Veneto, TV (Italy); Dudea, S.M. [Univ. Med. Pharm. ' ' Iuliu Hatieganu' ' , Department of Radiology, Cluj-Napoca (Romania); Grenier, N. [Pellegrin Hospital, Department of Radiology, Bordeaux (France); Oltmanns, G. [University Hospital of North Norway, Department of Radiology, Tromsoe (Norway); Ramchandani, P. [University of Pennsylvania, Department of Radiology, Perelman School of Medicine, Philadelphia, PA (United States); Stein, M.W. [Montefiore Medical Center, Department of Radiology, Albert Einstein College of Medicine, Bronx, NY (United States); Valentino, M. [Sant' Antonio Hospital, Department of Radiology, Tolmezzo, UD (Italy); Derchi, Lorenzo E. [University of Genoa, Department of Health Sciences, Genova (Italy); IRCCS Azienda Ospedaliera Universitaria San Martino IST, Radiologia d' Urgenza, Genova (Italy)

2016-03-15

To describe the imaging findings in a series of patients with mesothelioma of the tunica vaginalis testis. We reviewed clinical data, imaging findings and follow-up information in a series of 10 pathology-proven cases of mesothelioma (all had US; 2 had MR) of the tunica vaginalis. A variety of patterns could be observed, the most common (5/10) being a hydrocele with parietal, solid and hypervascular vegetations; one patient had a septated hydrocele with hypervascular walls; one had multiple, solid nodules surrounded by a small, physiological quantity of fluid; one a cystic lesion with thick walls and vegetations compressing the testis; two had a solid paratesticular mass. MR showed multiple small nodules on the surface of the tunica vaginalis in one case and diffuse thickening and vegetations in the other one; lesions had low signal intensity on T2-w images and were hypervascular after contrast injection. A preoperative diagnosis of mesotheliomas presenting as solid paratesticular masses seems very difficult with imaging. On the contrary, the diagnosis must be considered in patients in whom a hydrocele with parietal vegetations is detected, especially if these show high vascularity. (orig.)

Maksude langus on trend / Andres Lipstok

Index Scriptorium Estoniae

Lipstok, Andres, 1957-

2004-01-01

Ilmunud ka: Delovõje Vedomosti 14. apr. lk. 10; Paremad Uudised apr. nr. 4 lk. 7. Autor analüüsib Eesti maksupoliitikat ning leiab, et nii ettevõtluse maksustamise vähendamine kui üksikisiku tulumaksu alandamine on hädavajalik riigi majanduse elavdamiseks ning Eesti majandusliku arengu viimiseks EL-i liikmesriikide tasemele

Teresa Andrés Zamora (1907-1946: el compromiso social y político como arma de cultura

Directory of Open Access Journals (Sweden)

Seguí i Francés, Romà

2010-12-01

Full Text Available La biografía de Teresa Andrés Zamora (Villalba de los Alcores, 1907- París, 1946 es un claro ejemplo de cómo el compromiso de una mujer republicana a través de la cultura se transformó en beligerancia política. Este artículo quiere mostrar una imagen de Teresa Andrés más profunda que la de una bibliotecaria que militó en el PCE, pretendiendo reconstruir su recorrido vital tanto en la faceta académica como profesional y política, con el objetivo de presentar una evolución que va desde su paso por la Residencia de Señoritas hasta su prematura muerte en París. Teresa Andrés Zamora representa una generación de mujeres republicanas que fue leal a la II República, trabajando incansablemente durante la Guerra Civil, y que padeció el exilio en una Francia ocupada.

Giving Voice: Narrating silence, history and memory in André Brink ...

African Journals Online (AJOL)

This essay examines André Brink's two most recent novels, The Other Side of Silence (2002) and Before I Forget (2004), in terms of their voicing of silence and the rewriting of history and memory. Each has a theme familiar to Brink's readers – an historical story of colonial violence and violation avenged; and the recounting ...

Identification of Hedgehog Signaling Outcomes in Mouse Testis Development Using a Hanging Drop-Culture System1

Science.gov (United States)

Szczepny, Anette; Hogarth, Cathryn A.; Young, Julia; Loveland, Kate L.

2008-01-01

The Hedgehog (Hh) signaling pathway affects fetal testis growth. Recently, we described the dynamic cellular production of Hh signaling pathway components in juvenile and adult rodent testes. The Hh signaling is understood to regulate cord formation in the fetal testis, but minimal knowledge exists regarding how Hh signaling impacts the postnatal testis. To investigate this, we employed hanging drop cultures, which are used routinely in embryoid body formation. This approach has the advantage of using small media volume, and we examined its suitability for short-term culture of both murine embryonic gonads and adult testis tubules. The effects of cyclopamine, a specific Hh signaling inhibitor, were examined following culture of Embryonic Day 11.5 urogenital ridges (as control) and adult seminiferous tubule fragments for 24–48 h using histological, cell proliferation, and gene expression analyses. Cultured embryonic testes displayed generally normal cord structure, anti-Müllerian hormone (Amh) expression, and cell proliferation; known Hh target gene expression (Gli1, osteopontin, official symbol Spp1, and Amh) was altered in response to cyclopamine. Cultured adult tubules exhibited some loss of seminiferous epithelium organization over 48 h. Spermatogonia continued to proliferate, however, and no significant loss of viability was noted overall. Addition of cyclopamine significantly affected levels of Gli1, Igfbp6, Ccnd2 (cyclin D2), Ccnb1 (cyclin B1), Spp1, Kit, and Amh mRNAs; these genes have been shown previously to be expressed in Sertoli and germ cells. These novel results identify Hh target genes in the testis and demonstrate this signaling pathway likely affects cell survival and differentiation in the context of normal adult testis. PMID:18843087

Formalidades del derecho de autor en la era de internet: filtros de protección o facilitadores de licenciamiento

NARCIS (Netherlands)

van Gompel, S.

2016-01-01

El autor se refiere a los objetivos que inspirarían la reinstauración de formalidades de derechos de autor, señalando dos objetivos específicos, el de facilitar la adquisición de derechos de autor y el de mejorar el flujo de información al aumentar el dominio público. Ambos ayudarían a alcanzar el

Influence of Aluminium Chloride on Antioxidant System in the Testis and Epididymis of Rats

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Arumugam Kalaiselvi

2014-03-01

Full Text Available Background: In recent years, the use of chemicals in agriculture, industry, and public health has become so common that the environment is continuously contaminated by the toxic substance-like metals. Aluminum released due to anthropogenic activities such as mining and industrial uses. Aluminium has several industrial uses. The present study was designed to investigate the effect of aluminium chloride (AlCl3 on enzymatic and non-enzymatic antioxidants in the testis and epididymis of rats. Methods: Adult male rats were administered with aluminium chloride at two different doses, 50 mg and 100 mg/kg body weight, orally, daily for 45 days. At the end of the experimental period, the animals were sacrificed and their testis and the epididymis were removed. Antioxidant enzymes like catalase (CAT, superoxide dismutase (SOD, glutathione peroxidase (GPx, glutathione reductase (GR, and glutathione-s-transferase (GST were assayed. Lipid peroxidation (LPO, vitamin C, and vitamin E levels were also determined. Results: Aluminium chloride administration had no effect on the bodyweight of the animals but the weight of the testis and epididymis was decreased. Almost all the antioxidant enzymes studied markedly diminished in the testis and epididymis of aluminium chloride treated animals. The non-enzymatic antioxidants, vitamin C and vitamin E, also declined. Lipid peroxidation, on the other hand, significantly increased. The influence was found to be more in 100 mg treated rats when compared to 50 mg treated rats. Conclusions: The present study suggests the reproductive toxicity of aluminium by inducing the oxidative stress in the testis and epididymis and possible interference in sperm production and further maturational processes.

Localization of S-100 proteins in the testis and epididymis of poultry and rabbits

Science.gov (United States)

Abd-Elmaksoud, Ahmed; Marei, Hany E. S.

2014-01-01

The present investigation was conducted to demonstrate S-100 protein in the testis and epididymis of adult chickens, Sudani ducks, pigeons, and rabbits. This study may represent the first indication for the presence of S-100 in the male reproductive organs of these species and might therefore serve as a milestone for further reports. In the testis of chickens, pigeons and rabbits, intense S-100 was seen in Sertoli cells. S-100 was also seen in the endothelial lining of blood vessels in rabbit testis. On the contrary, no S-100 reaction was detected in the Sertoli cells of Sudani ducks. In epididymis, the localization of S-100 had varied according to species studied; it was seen in the basal cells (BC) of epididymal duct in duck, non-ciliated cells of the distal efferent ductules in pigeons and ciliated cells of the efferent ductules and BC of rabbit epididymis. Conversely, S-100 specific staining was not detected in the epithelial lining of the rooster and pigeon epididymal duct as well as the principal cells of the rabbit epididymis. In conclusion, the distribution of the S-100 proteins in the testis and epididymis might point out to its roles in the male reproduction. PMID:25276477

Dividend sõi kasumi ära / Andres Root

Index Scriptorium Estoniae

Root, Andres, 1956-

2004-01-01

Autor selgitab, miks kajastatakse välja makstud dividende kasumiaruandes ja näitab, kuidas see mõjutab ettevõtte finantstulemust. Tabelid: Kasumi kujunemine ja tulu maksustamine; Ettevõtte omakapital

Stage IE nonHodgkin's lymphoma of the testis: a need for a brief aggressive chemotherapy

International Nuclear Information System (INIS)

Roche, H.; Suc, E.; Pons, A.; Woodman, F.; Huguet-Rigal, F.; Caveriviere, P.; Carton, M.

1989-01-01

Primary nonHodgkin's lymphoma of the testis is a localized disease in 50 per cent of the cases. Clinical records and pathological material from 9 stage IE cancer patients treated at our institutions were reviewed. All but 1 patient had B cell type lymphomas of intermediate (6) or high (3) grade according to the Working Formulation. Mean survival was 49 months and actuarial survival was 74 per cent at 5 years. Chemotherapy differed with time and frequently was associated with subdiaphragmatic involved field and prophylactic contralateral testis radiotherapy. In view of the good prognosis of patients receiving doxorubicin-based chemotherapy and recent reports on low stage nonHodgkin's lymphoma we recommend an aggressive brief therapy for stage IE lymphoma of the testis after orchiectomy

Korterelamu Tallinnas Weizenbergi 29 = Apartment Building in Tallinn, at 29 Weizenbergi Street / Andres Alver

Index Scriptorium Estoniae

Alver, Andres, 1953-

2001-01-01

Puitvoodriga betoonist kastjas hoone. Projekteerija Alver Trummal Arhitektid. Arhitektid Andres Alver ja Tarmo Laht. Eriosad: Eesti Projekt. Projekt 1998, valmis 2000. 3 ill.: põhiplaan, välisvaade, Pille Lausmäe kujundatud korteri vaade

A Transnational World Fractured but Not Forgotten: British West Indian Migration to the Colombian Islands of San Andrés and Providence

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Sharika Crawford

2011-06-01

Full Text Available This article examines British West Indian migration to the Colombian archipelago of San Andrés and Providence in the late nineteenth to early twentieth century. While the United Fruit plantations, Panama Canal, oil fields in Venezuela, and railroad projects in Central America generated a strong demand for a large West Indian workforce, no such development took place on San Andrés and Providence. As a result, the profile of West Indian migration looks different than to the Spanish-speaking circum-Caribbean, with more professionals and merchants and fewer unskilled laborers. In the absence of mass migration, there was less hostility toward West Indian newcomers to San Andrés and Providence islands.

Kas Euroopas olid CIA salavanglad? / Andres Herkel

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Herkel, Andres, 1962-

2006-01-01

Dick Marty raportist USA Luure Keskagentuuri (CIA) oletatavatest salavanglatest Euroopas. Autor on seisukohal, et Euroopal tuleb igal juhul välja selgitada tõde CIA salavanglate olemasolu kohta, sest vastasel korral saab Venemaa argumendi inimõigustevastase tegevuse kaitseks. Vt. samas: CIA salavanglad ja -lennud Euroopas

Film, ruum ja narratiiv : "Mis juhtus Andres Lapeteusega?" ning "Viini postmark" / Eva Näripea

Index Scriptorium Estoniae

Näripea, Eva, 1980-

2011-01-01

Analüüsitakse narratiivi aegruumi loomise viise juhtumi analüüsi vormis, vaadeldes kaht eesti mängufilmi : G. Kromanovi "Mis juhtus Andres Lapeteusega?" (Tallinnfilm, 1966) ja Veljo Käsperi "Viini postmark" (Tallinnfilm, 1967)

Film, ruum ja narratiiv : "Mis juhtus Andres Lapeteusega?" ning "Viini postmark" / Eva Näripea

Index Scriptorium Estoniae

Näripea, Eva

2006-01-01

Analüüsitakse narratiivi aegruumi loomise viise juhtumi analüüsi vormis, vaadeldes kaht eesti mängufilmi : G. Kromanovi "Mis juhtus Andres Lapeteusega?" (Tallinnfilm, 1966) ja Veljo Käsperi "Viini postmark" (Tallinnfilm, 1967)

The epidemiology and transmissibility of Zika virus in Girardot and San Andres island, Colombia, September 2015 to January 2016

Science.gov (United States)

Rojas, DP; Dean, NE; Yang, Y; Kenah, E; Quintero, J; Tomasi, S; Ramirez, EL; Kelly, Y; Castro, C; Carrasquilla, G; Halloran, ME; Longini, IM

2016-01-01

Transmission of Zika virus (ZIKV) was first detected in Colombia in September 2015. As of April 2016, Colombia had reported over 65,000 cases of Zika virus disease (ZVD). We analysed daily surveillance data of ZVD cases reported to the health authorities of San Andres and Girardot, Colombia, between September 2015 and January 2016. ZVD was laboratory-confirmed by reverse transcription-polymerase chain reaction (RT-PCR) in the serum of acute cases within five days of symptom onset. We use daily incidence data to estimate the basic reproductive number (R0) in each population. We identified 928 and 1,936 reported ZVD cases from San Andres and Girardot, respectively. The overall attack rate for reported ZVD was 12.13 cases per 1,000 residents of San Andres and 18.43 cases per 1,000 residents of Girardot. Attack rates were significantly higher in females in both municipalities (p < 0.001). Cases occurred in all age groups with highest rates in 20 to 49 year-olds. The estimated R0 for the Zika outbreak was 1.41 (95% confidence interval (CI): 1.15–1.74) in San Andres and 4.61 (95% CI: 4.11–5.16) in Girardot. Transmission of ZIKV is ongoing in the Americas. The estimated R0 from Colombia supports the observed rapid spread. PMID:27452806

Autoralli MM-sarja ootab ees vaheaasta / Ivo Dobkevitš ; fotod Karli Saul

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Dobkevitsch, Ivo, 1973-

2009-01-01

Tehasetiimide majandusraskustest ja vähesest huvist autoralli MM-sarja vastu 2009. aastal ning FIA poolt kehtestatavatest tehnilistest muudatustest 2010. aastal. Samas: Urmo Aava hooaega vahele jätta ei kavatse

Testicular development and relationship between body weight, testis ...

African Journals Online (AJOL)

STORAGESEVER

2009-03-20

Mar 20, 2009 ... reports seem to indicate that boars with higher body and testis weight may ... in terms of loss of animals of good genetic standing may be of no practical ... weekly intervals until they reached 36 weeks of age. The ... Training of boars and semen collection. All in situ ..... on semen composition in the boar. Can.

Exploration, Invention and Imagination: The Myth of Icarus in André Bazin

NARCIS (Netherlands)

Joret, B.; Viegas, S.; Teixeira, M.T.

2015-01-01

In this essay, I intend to elucidate the ontological implications of André Bazin’s integral realism: "a recreation of the world in its own image." The connection that he draws between the world and the image is in harmony with his mythical project for cinema, which argues that an imaginative myth

Instrucciones a los Autores

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revistaiid@ uptc.edu.co

2006-12-01

Full Text Available Ingeniería,  Investigación y Desarrollo publica  trabajos inéditos sobre geología, minería, electrónica, industrial y ciencias afines, en español. Podrán publicarse artículos originales, de investigación y/o innovación tecnológica, de revisión o réplicas de publicaciones de la propia revista. Además, se podrán incluir  resúmenes de  tesis,  reseñas de  libros y comunicaciones de  interés a estas profesiones.Para  la presentación de  los artículos  se debe  tener en cuenta que: Los artículos serán evaluados por   el comité Editorial y un árbitro, el que se reserva el derecho de decidir sobre su publicación. Los  trabajos enviados a  Ingeniería,  Investigación y Desarrollo, no podrán ser sometidos simultáneamente a evaluación por otro medio de publicación. El contenido de los trabajos   es responsabilidad exclusiva de sus autores. No se devolverán los originales de los trabajos

Vene faktor ehk poloonium 210 / Andres Herkel

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Herkel, Andres, 1962-

2007-01-01

Autor mõtestab lahti nn pärsitud kriitika sündroomi, mille järgi Mihhail Gorbatshovist alates on Vene võimu saatnud üks kustumatu müüt: Vene võimuga peab leppima, sest olukord on plahvatusohtlik ja uus, mis tuleb, on kindlasti hullem

Effect of sildenafil citrate (Viagra) and ethanol on the Albino rat testis: a scanning electron microscopic approach.

Science.gov (United States)

Sivasankaran, T G; Udayakumar, R; Elanchezhiyan, C; Sabhanayakam, Selvi

2008-02-01

The effects of sildenafil citrate with ethanol on the rat testis was studied using scanning electron microscopy. Male Albino rats were divided into 8 groups, each being treated for a maximum of 45 days as follows. In the 4 short-term treatment groups, control rats were administered normal saline orally, whereas experimental animals were fed sildenafil citrate (Viagra) 1 microg/g with 18% ethanol (5 g/kg body weight), which was given orally as a single dose. After 1, 2.5, 4 and 24h the rats were killed. In the 4 long-term treatment groups, daily continuous doses of drug and ethanol with a single dosage were given for 15, 30 and 45 days and the animals killed 4h after the last dosage. Changes in the testis were compared with the normal healthy rat testis. The use of a scanning electron microscope for evaluation of the changes in the testis is more suitable for observation of the surface and morphological shapes of the tissue structures.

The structural and functional state of hemomicrocirculatory bed and parenchyma of the testis in varicocele

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O. E. Khallo

2015-08-01

Full Text Available Varicose veins of the spermatic cord and testis membranes play a key role in the development of male infertility. Aim. To study the structural features of the bloodstream and testicular parenchyma in terms of varicose veins of the spermatic cord and testis membranes. Meyhods and results. In 23 testicular preparations taken from men of mature age convoluted seminiferous tubules diameter, number of cells of spermatogenic epithelium and interstitial endocrinocytes nuclei volume were studied using macro- and microscopic morphometric methods. It was established that in varicocele testis volume, diameter of convoluted seminiferous tubules and interstitial endocrinocytes nuclei volume significantly reduced. Conclusion. This indicates the presence of circulatory hypoxia of testicles, which leads to a decrease in the volume of interstitial endocrinocytes nuclei by 31%, thereby reducing their functional properties.

CRISPR/Cas9 Promotes Functional Study of Testis Specific X-Linked Gene In Vivo.

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Minyan Li

Full Text Available Mammalian spermatogenesis is a highly regulated multistage process of sperm generation. It is hard to uncover the real function of a testis specific gene in vitro since the in vitro model is not yet mature. With the development of the CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated 9 system, we can now rapidly generate knockout mouse models of testis specific genes to study the process of spermatogenesis in vivo. SYCP3-like X-linked 2 (SLX2 is a germ cell specific component, which contains a Cor1 domain and belongs to the XLR (X-linked, lymphocyte regulated family. Previous studies suggested that SLX2 might play an important role in mouse spermatogenesis based on its subcellular localization and interacting proteins. However, the function of SLX2 in vivo is still elusive. Here, to investigate the functions of SLX2 in spermatogenesis, we disrupted the Slx2 gene by using the CRISPR/Cas9 system. Since Slx2 is a testis specific X-linked gene, we obtained knockout male mice in the first generation and accelerated the study process. Compared with wild-type mice, Slx2 knockout mice have normal testis and epididymis. Histological observation of testes sections showed that Slx2 knockout affected none of the three main stages of spermatogenesis: mitosis, meiosis and spermiogenesis. In addition, we further confirmed that disruption of Slx2 did not affect the number of spermatogonial stem cells, meiosis progression or XY body formation by immunofluorescence analysis. As spermatogenesis was normal in Slx2 knockout mice, these mice were fertile. Taken together, we showed that Slx2 itself is not an essential gene for mouse spermatogenesis and CRISPR/Cas9 technique could speed up the functional study of testis specific X-linked gene in vivo.

Effect of varicocelectomy on testis volume and semen parameters in adolescents: a meta-analysis

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Tie Zhou

2015-01-01

Full Text Available Varicocele repair in adolescent remains controversial. Our aim is to identify and combine clinical trials results published thus far to ascertain the efficacy of varicocelectomy in improving testis volume and semen parameters compared with nontreatment control. A literature search was performed using Medline, Embase and Web of Science, which included results obtained from meta-analysis, randomized and nonrandomized controlled studies. The study population was adolescents with clinically palpable varicocele with or without the testicular asymmetry or abnormal semen parameters. Cases were allocated to treatment and observation groups, and testis volume or semen parameters were adopted as outcome measures. As a result, seven randomized controlled trials (RCTs and nonrandomized controlled trials studying bilateral testis volume or semen parameters in both treatment and observation groups were identified. Using a random effect model, mean difference of testis volume between the treatment group and the observation group was 2.9 ml (95% confidence interval [CI]: 0.6, 5.2; P< 0.05 for the varicocele side and 1.5 ml (95% CI: 0.3, 2.7; P< 0.05 for the healthy side. The random effect model analysis demonstrated that the mean difference of semen concentration, total semen motility, and normal morphology between the two groups was 13.7 × 10 6 ml−1 (95% CI: −1.4, 28.8; P = 0.075, 2.5% (95% CI: −3.6, 8.6; P= 0.424, and 2.9% (95% CI: −3.0, 8.7; P= 0.336 respectively. In conclusion, although varicocelectomy significantly improved bilateral testis volume in adolescents with varicocele compared with observation cases, semen parameters did not have any statistically significant difference between two groups. Well-planned, properly conducted RCTs are needed in order to confirm the above-mentioned conclusion further and to explore whether varicocele repair in adolescents could improve subsequently spontaneous pregnancy rates.

Tallinna Lennujaama kauba- ja tolliterminaal. Lennujaama 2, Tallinn / Andres Põime

Index Scriptorium Estoniae

Põime, Andres

1998-01-01

Kaubateeninduskeskuse puhul on tegemist suure, plaanimõõtudes 36x102 meetrise metallkonstruktsioonis, sandwich tüüpi paneelidega kaetud laohoonega, kus ühelt poolt tuuakse tollitav kaup lennukitelt sisse ja teiselt poolt viiakse tollitud kaup välja. Peatöövõtja : Normanni Linnagrupi AS. Ehitaja : Merko. Peaprojekteerija : K-Projekt. Arhitektuurne lahendus : Stuudio 3. Arhitekt Andres Põime ; töögrupp Vivian Oruvee, Tiiu Raudsepp, Reet Põime. Projekt 1997-98, valmis 1998.

Mida teeks tulevane kultuuriminister 500 miljoni krooniga? / interv. Andres Keil

Index Scriptorium Estoniae

2007-01-01

Suuremate erakondade kultuurispetsialistid (kultuuriministrikandidaadid) Urmas Paet, Andres Herkel, Peeter Jalakas, Indrek Saar, Jaak Allik, samuti kultuuriminister Raivo Palmaru vastavad küsimustele, mis on suurimad ohud eesti keele ja rahvuskultuuri säilimisele, milline on kultuuriministeeriumi ja -ministri portfelli staatus praeguses valitsuses, kas kultuuri rahastamine riigieelarvest on piisav, mille poolest erineb nende erakonna nägemus kultuuripoliitikast teiste erakondade omast, kuhu nad suunaksid 50, 500 miljonit, kui see oleks nende käsutuses

Indices de Munibe (Antropologia-Arkeologia. Autores y Materias (Años 1949-1999

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Koro Mariezkurrena

1999-01-01

Full Text Available En 1973, al cumplir la revista Munibe 25 años, J. ELOSEGUI IRAZUSTA publicó los índices de todos los trabajos publicados en la misma hasta la fecha. Posteriormente hemos continuado esta labor publicando cada cinco años índices de ese período. Los dos primeros quiquenios recogen los índices de todos los temas que publicaba la revista, a saber, Geología, Botánica, Zoología, Antropología y Arqueología. Al dividirse en 1985 la revista en dos, Ciencias naturales por un lado y Antropologia-Arqueología por otro, a partir de los índices del quinquenio 1983-1988, venimos recogiendo solamente los artículos referentes a estos últimos temas. En los presentes índices recogemos todos los artículos, notas y recensiones referentes a Antropología y Arqueología publicados en los 50 años de vida de la revista, entresacando los que aparecieron cuando la revista era única y recogiendo todos los aparecidos después de la división. Estos índices los presentamos en tres apartados : Indice alfabético de autores, ordenados dentro de cada autor por años Indice por años de revista, ordenados los autores alfabéticamente Indice por temas.

Aspiration and tetracycline sclerotherapy of primary vaginal hydrocoele of testis in adults.

Science.gov (United States)

Ali, Johar; Anwar, Waqas; Akbar, Mohammad; Akbar, Syed Ali; Zafar, Arshad

2008-01-01

Primary Vaginal Hydrocoele of Testis is a common condition which is primarily treated surgically. Many patients with Hydrocoele of testis are either not willing or are unfit for surgery. This study was done to know the safety, efficacy and out come of tetracycline induced sclerotherapy of Primary Vaginal Hydrocoele of Testis in adults. This quasi experimental study was done in Shahina Jamil Hospital, attached with Frontier Medical College and Ayub Teaching Hospital, Abbottabad from March 2006 to April, 2007. Thirty-seven patients with primary vaginal hydrocoele were included in the study. Aspiration and instillation of Tetracycline was done after spermatic cord block with 2% lignocaine. Procedure time, Peri and Post-procedure complications, number of injections for cure and patients' satisfaction with the procedure were recorded. Patients were discharged home 3 to 4 hours after the procedure and followed up after one week, one month, three months and six months. Direct admission and re-admissions were recorded. The mean age of patients was 47 years. Mean procedure time was 45 minutes. All patients were cured. Mild postoprocedure pain occurred in 12 (40%), moderate pain in 14 (46%) patients and severe pain in 4 (13.3%) patients. No patient developed haematoma or local infection. One patient (3.3%) had micturition problem. Two (6.6%) patients had minimal recurrence. One injection was sufficient for cure in all patients. 28 (93%) patients were satisfied while 2 (6.6%) patients were not satisfied with this procedure. No patient was admitted in the hospital after the procedure. Aspiration and injection of tetracycline in Primary vaginal Hydrocoele of Testis in adults is safe, effective and very economical procedure.

Aspiration and tetracycline sclerotherapy of primary vaginal hydrocoele of testis in adults

International Nuclear Information System (INIS)

Ali, J.; Anwar, W.

2008-01-01

Primary Vaginal Hydrocoele of Testis is a common condition which is primarily treated surgically. Many patients with Hydrocoele of testis are either not willing or are unfit for surgery. This study was done to know the safety, efficacy and out come of tetracycline induced sclerotherapy of Primary Vaginal Hydrocoele of Testis in adults. This quasi experimental study was done in Shahina Jamil Hospital, attached with Frontier Medical College and Ayub Teaching Hospital, Abbottabad from March 2006 to April, 2007. Thirty-seven patients with primary vaginal hydrocoele were included in the study. Aspiration and instillation of Tetracycline was done after spermatic cord block with 2% lignocaine. Procedure time, Peri and Post-procedure complications, number of injections for cure and patients satisfaction with the procedure were recorded. Patients were discharged home 3 to 4 hours after the procedure and followed up after one week, one month, three months and six months. Direct admission and re-admissions were recorded. The mean age of patients was 47 years. Mean procedure time was 45 minutes. All patients were cured. Mild postoprocedure pain occurred in 12 (40%), moderate pain in 14 (46%) patients and severe pain in 4 (13.3%) patients. No patient developed haematoma or local infection. One patient (3.3%) had micturition problem. Two (6.6%) patients had minimal recurrence. One injection was sufficient for cure in all patients, 28 (93%) patients were satisfied while 2 (6.6%) patients were not satisfied with this procedure. No patient was admitted in the hospital after the procedure. Aspiration and injection of tetracycline in Primary vaginal Hydrocoele of Testis in adults is safe, effective and very economical procedure. (author)

La astronomía de un humanista, Juan Andrés

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José Antonio SANDUVETE CHAVES

2009-11-01

Full Text Available RESUMEN: La páginas que siguen pretenden ofrecer una visión de conjunto del análisis que de la historia de la Astronomía realiza Juan Andrés, desde los orígenes de la humanidad hasta el siglo XVIII. Este análisis, incluido en su monumental obra Origen, progresos y estado actual de toda la literatura, destaca por su modernidad y precisión, constituyendo, por tanto, una interesante base de comparación entre la visión de la ciencia astronómica del humanismo ilustrado y la que pervive en la actualidad.ABSTRACT: The following pages attempt to offer a full view of the research into the history of astronomy made by Juan Andrés, from the beginning of human culture until the 18th century. This analysis, included in a broader work called Origen, progresos y estado de toda la literatura, stands out on account of its modern and precise ideas, thus representing an interesting knowledge base for comparing the view of astronomy during the Enlightenment with that of the present.

Medidas cautelares innominadas en la protección de los derechos de autor y conexos en Colombia

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Nixon Jefrey Gil Aguirre

2016-12-01

Full Text Available Actualmente, el ejercicio de funciones jurisdiccionales atribuidas a las autoridades administrativas ha generado interpretaciones judiciales confusas, en la aplicación de medidas cautelares innominadas para la protección de derechos de autor y conexos en Colombia; así lo evidencia el análisis realizado a las medidas cautelares descritas en la Ley 1493 del año 2011, que otorgó competencias de inspección, vigilancia y control sobre las sociedades de gestión colectiva de derechos de autor y conexos; en este sentido se requiere describir las funciones jurisdiccionales de la Dirección Nacional de Derecho de Autor respecto a las medidas cautelares y su importancia en la protección de los derechos de autor y conexos, al igual que analizar las medidas cautelares innominadas desde su origen, las características y lo propuesto por la Corte Constitucional en materia de funciones jurisdiccionales de la Dirección Nacional de Derecho de Autor y respecto de la procedencia de las medidas cautelares innominadas como competencia de esta entidad. Se concluye que las medidas cautelares nominadas no son suficientes, y que se hace necesario acudir a las medidas cautelares innominadas, como herramienta jurídica del funcionario administrativo, sin que ello implique arbitrariedad y prejuzgamiento en el proceso.

Eesti Metodisti Kirik : Balti Misjoni Keskus, Narva mnt. 51, Tallinn = Estonian Methodist Church / Vilen Künnapu

Index Scriptorium Estoniae

Künnapu, Vilen, 1948-

2000-01-01

Projekteerija Arhitektuuribüroo Künnapu & Padrik. Arhitektid Vilen Künnapu, Ain Padrik. Konstruktsioonide autor Andres Laur. Sisekujundajad Argo ja Katrin Vaikla. Projekt 1994, valmis 2000. Kirik on klaasja pikliku koolitiivaga (teoloogiline seminar). 7 ill.: I korruse plaan, lõige, välis- ja sisevaated

Andres Herkel : Venemaa esindaja ENPA presidendiks ei sobi / Haldi Ellam, Ravil Khair Al-Din

Index Scriptorium Estoniae

Ellam, Haldi

2007-01-01

Vene ajalehe Kommersant väitel on Eesti parlamendi süüdistused ENPA presidendi Rene van der Lindeni vastu seotud Mihhail Margelovi võimaliku valimisega uueks presidendiks. Kristiina Ojuland ja Andres Herkel lükkavad väite tagasi

Congenital juvenile granulosa cell tumor of the testis: Case report and literature review

Directory of Open Access Journals (Sweden)

Carolina Talini

2016-07-01

Full Text Available Juvenile granulosa cell tumor (JGCT is a very rarely diagnosed benign tumor, accounting for 1.2% of all prepubertal testicular tumors. A full-term healthy neonate was diagnosed with a painless left scrotal mass. During evaluation it was identified to have about two times the volume of the contralateral testis, presenting a firm consistency, not as hard as the consistency of a prenatal testicular torsion. Doppler ultrasound detected a multicystic left testicular mass, with normal blood flow, but failed in detecting normal-appearing testis. Human chorionic gonadotropin (β-HCG and serum alpha-fetoprotein (AFP were normal. Inguinal approach was performed, section of the lesion was sent to frozen biopsy and excluded yolk sac tumor, and however the impossibility of detecting normal testis tissue indicated orchiectomy with high ligation of the spermatic cord. Histological evaluation demonstrated gray testicular parenchyma with multicystic aspect fulfilled with yellow fluid. The usual clinical presentation of JGCT is a painless scrotal mass, radiological imaging demonstrates a multicystic tumor. Tumoral markers levels are normal and the standard treatment is the inguinal orchiectomy.

AND/R: Advanced neutron diffractometer/reflectometer for investigation of thin films and multilayers for the life sciences

International Nuclear Information System (INIS)

Dura, Joseph A.; Pierce, Donald J.; Majkrzak, Charles F.; Maliszewskyj, Nicholas C.; McGillivray, Duncan J.; Loesche, Mathias; O'Donovan, Kevin V.; Mihailescu, Mihaela; Perez-Salas, Ursula; Worcester, David L.; White, Stephen H.

2006-01-01

An elastic neutron scattering instrument, the advanced neutron diffractometer/reflectometer (AND/R), has recently been commissioned at the National Institute of Standards and Technology Center for Neutron Research. The AND/R is the centerpiece of the Cold Neutrons for Biology and Technology partnership, which is dedicated to the structural characterization of thin films and multilayers of biological interest. The instrument is capable of measuring both specular and nonspecular reflectivity, as well as crystalline or semicrystalline diffraction at wave-vector transfers up to approximately 2.20 A -1 . A detailed description of this flexible instrument and its performance characteristics in various operating modes are given

Lack of ADAM2, CALR3 and SAGE1 Cancer/Testis Antigen Expression in Lung and Breast Cancer

DEFF Research Database (Denmark)

Maheswaran, Emeaga; Pedersen, Christina B; Ditzel, Henrik J

2015-01-01

and antigenic properties, but the expression patterns of most of the more than 200 identified cancer/testis antigens in various cancers remain largely uncharacterized. In this study, we investigated the expression of the cancer/testis antigens ADAM2, CALR3 and SAGE1 in lung and breast cancer, the two most...... frequent human cancers, with the purpose of providing novel therapeutic targets for these diseases. We used a set of previously uncharacterized antibodies against the cancer/testis antigens ADAM2, CALR3 and SAGE1 to investigate their expression in a large panel of normal tissues as well as breast and lung...... cancers. Staining for the well-characterized MAGE-A proteins was included for comparison. Immunohistochemical staining confirmed previous mRNA analysis demonstrating that ADAM2, CALR3 and SAGE1 proteins are confined to testis in normal individuals. Negative tissues included plancenta, which express many...

Male-biased genes in catfish as revealed by RNA-Seq analysis of the testis transcriptome.

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Fanyue Sun

Full Text Available BACKGROUND: Catfish has a male-heterogametic (XY sex determination system, but genes involved in gonadogenesis, spermatogenesis, testicular determination, and sex determination are poorly understood. As a first step of understanding the transcriptome of the testis, here, we conducted RNA-Seq analysis using high throughput Illumina sequencing. METHODOLOGY/PRINCIPAL FINDINGS: A total of 269.6 million high quality reads were assembled into 193,462 contigs with a N50 length of 806 bp. Of these contigs, 67,923 contigs had hits to a set of 25,307 unigenes, including 167 unique genes that had not been previously identified in catfish. A meta-analysis of expressed genes in the testis and in the gynogen (double haploid female allowed the identification of 5,450 genes that are preferentially expressed in the testis, providing a pool of putative male-biased genes. Gene ontology and annotation analysis suggested that many of these male-biased genes were involved in gonadogenesis, spermatogenesis, testicular determination, gametogenesis, gonad differentiation, and possibly sex determination. CONCLUSION/SIGNIFICANCE: We provide the first transcriptome-level analysis of the catfish testis. Our analysis would lay the basis for sequential follow-up studies of genes involved in sex determination and differentiation in catfish.

Cell-selective determination of trace elements in testis by SR-XRF analysis with nanoprobe

International Nuclear Information System (INIS)

Homma-Takeda, Shino; Nishimura, Yoshikazu; Watanabe, Yoshito; Yukawa, Masae; Ueno, Shunji; Terada, Yasuko

2005-01-01

Organotin compounds are widely used in industry and its environmental contamination by these compounds has recently become a concern. It is known that they act as endocrine disruptors but details of the dynamics of Sn in reproductive organs are still unknown. In the present study, we attempted to determine Sn in the testis of rats exposed to tributyltin chloride (TBTC) cell-selectively by synchrotron radiation X-ray florescence analysis with nanoprobe. TBTC was orally administered to rats at a dose of 45 μmol/kg per day for 3 days. One day later, Sn was detected in spermatozoa at the stage VIII seminiferous tubule, which are the final step of spermatogenesis in the testis. Sn levels in the microdissectioned seminiferous tubules determined by inductively coupled argon plasma-mass spectrometry were approximately equivalent to that in the testis. These data indicate that Sn accumulates in germ cells as well as in spermatozoa in a short period of TBTC exposure. (author)

The roles of TAM receptor tyrosine kinases in the mammalian testis and immunoprivileged sites.

Science.gov (United States)

Deng, Tingting; Chen, Qiaoyuan; Han, Daishu

2016-01-01

Three members of a receptor tyrosine kinase family, including Tyro3, Axl, and Mer, are collectively called as TAM receptors. TAM receptors have two common ligands, namely, growth arrest specific gene 6 (Gas6) and protein S (ProS). The TAM-Gas6/ProS system is essential for phagocytic removal of apoptotic cells, and plays critical roles in regulating immune response. Genetic studies have shown that TAM receptors are essential regulators of the tissue homeostasis in immunoprivileged sites, including the testis, retina and brain. The mechanisms by which the TAM-Gas6/ProS system regulates the tissue homeostasis in immunoprivileged sites are emerging. The roles of the TAM-Gas6/ProS system in regulating the immune privilege were intensively investigated in the mouse testis, and several studies were performed in the eye and brain. This review summarizes our current understanding of TAM signaling in the testis and other immunoprivileged tissues, as well as highlights topics that are worthy of further investigation.

Sox9 induces testis development in XX transgenic mice

NARCIS (Netherlands)

Vidal, V. P.; Chaboissier, M. C.; de rooij, D. G.; Schedl, A.

2001-01-01

Mutations in SOX9 are associated with male-to-female sex reversal in humans. To analyze Sox9 function during sex determination, we ectopically expressed this gene in XX gonads. Here, we show that Sox9 is sufficient to induce testis formation in mice, indicating that it can substitute for the

Roles of piRNAs in microcystin-leucine-arginine (MC-LR) induced reproductive toxicity in testis on male offspring.

Science.gov (United States)

Zhang, Ling; Zhang, Hui; Zhang, Huan; Benson, Mikael; Han, Xiaodong; Li, Dongmei

2017-07-01

In the present study, we evaluated the toxic effects on the testis of the male offspring of MC-LR exposure during fetal and lactational periods. Pregnant females were distributed into two experimental groups: control group and MC-LR group which were exposed to 0 and 10 μg/L of MC-LR, respectively, through drinking water separately during fetal and lactational periods. At the age of 30 days after birth, the male offspring were euthanized. The body weight, testis index, and histomorphology change were observed and the global changes of piwi-interacting RNA (piRNA) expression were evaluated. The results revealed that MC-LR was found in the testis of male offspring, body weight and testis index decreased significantly, and testicular tissue structure was damaged in the MC-LR group. In addition, the exposure to MC-LR resulted in an altered piRNA expression profile and an increase of the cell apoptosis and a decrease of the cell proliferation in the testis of the male offspring. It was reasonable to speculate that the toxic effects on reproductive system of the male offspring in MC-LR group might be mediated by piRNAs through the regulation of the target genes. As far as we are aware, this is the first report showing that MC-LR could play a role in disorder of proliferative and cell apoptosis in the testis of the male offspring by the maternal transmission effect of toxicity. Copyright © 2017 Elsevier Ltd. All rights reserved.

De niet-scrotale testis: huidige standpunten van de Werkgroep Kinderurologie van de Nederlandse Vereniging voor Urologie [Undescended testis: Current views and advice for treatment

NARCIS (Netherlands)

Hack, W.W.M.; Sijstermans, K.; Voort-Doedens, L.M. van der; Meijer, R.W.; Heij, H.A.; Delemarre-van de Waal, H.A.; Pierik, F.H.

2008-01-01

Eerder dit jaar verschenen in dit tijdschrift drie artikelen gewijd aan de niet-scrotale testis (NST).1-3 Ze hebben tot veel discussie geleid binnen de Werkgroep Kinderurologie (WGKU) van de Nederlandse Vereniging voor Urologie (NVU), hetgeen resulteerde in dit commentaar. Vooral de artikelen van

Recent adverse trends in semen quality and testis cancer incidence among Finnish men

DEFF Research Database (Denmark)

Jorgensen, N.; Vierula, M.; Jacobsen, R.

2011-01-01

Impaired semen quality and testicular cancer may be linked through a testicular dysgenesis syndrome of foetal origin. The incidence of testis cancer has been shown to increase among Finnish men, whereas there is no recent publication describing temporal trends in semen quality. Therefore, we...... carried out a prospective semen quality study and a registry study of testis cancer incidence among Finnish men to explore recent trends. A total of 858 men were investigated in the semen quality study during 1998-2006. Median sperm concentrations were 67 (95% CI 57-80) million/mL, 60 (51-71) and 48 (39...

Testicular sparing surgery in small testis masses: A multinstitutional experience

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Andrea B. Galosi

2016-12-01

Full Text Available Introduction: The incidence of benign testicular tumors is increasing in particular in small lesion incidentally found at scrotal ultrasonography. Primary aim of this study was to perform radical surgery in malignant tumor. Secondary aim was to verify the efficacy of the diagnostic-therapeutic pathway recently adopted in management of small masses with testis sparing surgery in benign lesions. Materials and methods: In this multicenter study, we reviewed all patients with single testis lesion less than 15 mm at ultrasound as main diameter. We applied the diagnostic-therapeutic pathway described by Sbrollini et al. (Arch Ital Urol Androl 2014; 86:397 which comprises: 1 testicular tumor markers, 2 repeated scrotal ultrasound at the tertiary center, 3 surgical exploration with inguinal approach, intraoperative ultrasound, and intraoperative pathological examination. Definitive histology was reviewed by a dedicated uro-pathologist. Results: Twenty-eight patients completed this clinical flowchart. The mean lesion size was 9.3 mm (range 2.5-15. Testicular tumor markers were normal except in a case. Intraoperative ultrasound was necessary in 8/28 cases. We treated 11/28 (39.3% with immediate radical orchiectomy and 17/28 (60.7% with testis-sparing surgery. Definitive pathological results were: malignant tumor in 6 cases (seminoma, benign tumor in 10 cases (5 Leydig tumors, 2 Sertoli tumors, 1 epidermoid cyst, 1 adenomatoid tumor, 1 angiofibroma, benign disease in 11 (8 inflammation with haemorragic infiltration, 2 tubular atrophy, 1 fibrosis, and normal parenchyma in 1 case. We observed a good concordance between frozen section examination and definitive histology. Any malignant tumor was treated conservatively. Any delayed orchiectomy was necessary based on definitive histology. Conclusions: The incidence of benign lesions in 60% of small testis lesions with normal tumor markers makes orchiectomy an overtreatment. Testicular sparing surgery of single

Ecrire à la suite de : Andrée Lacelle, Andrée Christensen et Jacques Flamand, Paul Savoie et Dyane Léger

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Catherine Parayre

2012-05-01

Full Text Available « Ecrire à la suite de » est un procédé d’écriture courant dans la littérature, qu’il s’agisse de mettre en relief l’intertextualité de l’œuvre (par exemple, en incluant des citations, de s’adonner à un travail basé sur l’intermédialité (par exemple, dans un texte rédigé à partir de photographies ou encore d’écrire à quatre mains, lorsqu’un des deux auteurs ajoute son texte à celui du partenaire d’écriture. Ne faisant pas exception, les littératures francophones du Canada pratiquent tout aussi fréquemment cette écriture de l’après. Le présent article en examinera quelques exemples dans des œuvres de nature introspective : La lumière et l’heure : poèmes et carnets (2004 d’Andrée Lacelle, avec des tableaux de Réjine Halimi ; Lithochronos ou le premier vol de la pierre (1999 d’Andrée Christensen et Jacques Flamand, avec des photographies de Christensen ; et L’incendiaire (2008 de Paul Savoie et Dyane Léger. L’analyse montrera que l’écriture « à la suite de », aussi variées qu’en soient les manifestations, non seulement met en évidence la présence de l’auteur dans ces textes, mais a aussi pour résultat, dans ces œuvres méditatives, de dédramatiser et d’amenuiser l’intensité de la réflexion existentielle.

André Gide, Gide & Amrouche. Correspondance (1928-1950)

OpenAIRE

Amadessi, Veronica

2016-01-01

En 1928, le jeune Jean el-Mouhoub Amrouche captive l’attention d’André Gide dans une lettre qu’il lui adresse personnellement. À cette époque, la réputation de l’auteur de L’Immoraliste ne cesse de grandir, alors que l’expéditeur n’est qu’un «brillant» normalien inconnu au grand public. Il s’agit toutefois d’un jeune kabyle aux idées bien précises, qui exprime, dans cette première missive, sa volonté de se faire le porte-parole de l’identité kabyle tout en préservant son amour pour la France....

Sofi Oksase luule muutus Vanemuises teatrireaalsuseks / Andres Laasik

Index Scriptorium Estoniae

Laasik, Andres, 1960-2016

2010-01-01

18. septembril Vanemuise teatri väikeses majas esietendunud lavastusest "Puhastus", autor Sofi Oksanen, lavastaja Liisa Smith. Vaatluse all on sündmused Eesti lähiminevikust (1936-1992). "Puhastust" mängitakse Helsingis Kansallisteatteri laval kaks korda jaanuaris 2011

Estonian Golf & Country Club / Liina Jänes

Index Scriptorium Estoniae

Jänes, Liina, 1977-

2005-01-01

Estonian Golf & Country Club'i etnomodernistlik golfikeskus ja klubihoone Jõelähtmel. Projekteerija: Arhitektuuristuudio Siim & Kreis. Autor Andres Siim. Konstruktor: Resand. Sisekujundaja Juta Lember (SAB Lember & Padar). Projekt 2004, valmis 2005. Ill.: I ja II korruse plaan, 3 värv. välis ja 3 sisevaadet

Trisomía 21: autoría reivindicada

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Horacio Rivera

2016-01-01

Full Text Available Esta reseña recapitula diversas circunstancias relativas al descubrimiento en 1958-1959 de la trisomía 21 propia del síndrome de Down y a la participación de los tres autores protagonistas. En particular, se subraya que fue Marthe Gautier quien en realidad hizo los cultivos celulares, analizó las metafases y se percató que los pacientes con síndrome de Down tenían 47 cromosomas. En consecuencia, es claro que su crucial contribución no había recibido, hasta la actualidad, el crédito apropiado.

Effects of estradiol and FSH on maturation of the testis in the hypogonadal (hpg mouse

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Mayhew Terry M

2008-01-01

Full Text Available Abstract Background The hypogonadal (hpg mouse is widely used as an animal model with which to investigate the endocrine regulation of spermatogenesis. Chronic treatment of these GnRH-deficient mice with estradiol is known to induce testicular maturation and restore qualitatively normal spermatogenesis. The aim of the current studies was to investigate whether these effects of estradiol are direct effects in the testis, or indirect actions via paradoxical stimulation of FSH secretion from the pituitary gland. Methods Initially, Western blot and immunohistochemistry were used to analyse tissues from hpg mice to identify potential sites of action of estradiol. In the main study, hpg mice were treated for 50 days with either an estradiol implant or daily injections of recombinant human FSH, or a combination of both, to determine whether estradiol would have an additive or synergistic effect with FSH on testis development, as assessed by histological analysis and stereological quantification of Leydig, Sertoli and germ cell proliferation. Results Western blot analysis revealed ERα immunoreactive bands of appropriate molecular weight in extracts of testis and pituitary glands from hpg mice, and immunohistochemical studies confirmed ERα in nuclei of anterior pituitary cells and Leydig and peritubular cells in hpg mice. Histological and morphometric analyses revealed that estradiol treatment alone was as effective as FSH in promoting Sertoli cell production and proliferation of the seminiferous epithelium, resulting in the production of elongating spermatids. Combined estradiol and FSH treatment did not produce a greater effect than either treatment alone, though an increased dose of FSH significantly increased seminiferous tubule volume and testis weight and increase Sertoli cell numbers further within the same time frame. In contrast, estradiol caused substantial increases in the wet weight of the seminal vesicles, whereas FSH was without effect on

Tõnu Anton kahtlustab linnaisasid omakasu jahtimises / Tõnu Anton, Andres Kõiv, Ando Hagel ; interv. Ulis Guth

Index Scriptorium Estoniae

Anton, Tõnu, 1942-

2004-01-01

Võru linnavolikogu opositsiooni kuuluv keskerakondlane Tõnu Anton kritiseerib sotsiaalabitalituse ruumide remondirahade kasutamist ja kahtlustab linnavalitsust riigihangete käigus raha kõrvaldamises. Linnapea Ando Hagel ja abilinnapea Andres Kõiv lükkavad süüdistused tagasi

Acetylation-Dependent Chromatin Reorganization by BRDT, a Testis-Specific Bromodomain-Containing Protein

Science.gov (United States)

Pivot-Pajot, Christophe; Caron, Cécile; Govin, Jérôme; Vion, Alexandre; Rousseaux, Sophie; Khochbin, Saadi

2003-01-01

The association between histone acetylation and replacement observed during spermatogenesis prompted us to consider the testis as a source for potential factors capable of remodelling acetylated chromatin. A systematic search of data banks for open reading frames encoding testis-specific bromodomain-containing proteins focused our attention on BRDT, a testis-specific protein of unknown function containing two bromodomains. BRDT specifically binds hyperacetylated histone H4 tail depending on the integrity of both bromodomains. Moreover, in somatic cells, the ectopic expression of BRDT triggered a dramatic reorganization of the chromatin only after induction of histone hyperacetylation by trichostatin A (TSA). We then defined critical domains of BRDT involved in its activity. Both bromodomains of BRDT, as well as flanking regions, were found indispensable for its histone acetylation-dependent remodelling activity. Interestingly, we also observed that recombinant BRDT was capable of inducing reorganization of the chromatin of isolated nuclei in vitro only when the nuclei were from TSA-treated cells. This assay also allowed us to show that the action of BRDT was ATP independent, suggesting a structural role for the protein in the remodelling of acetylated chromatin. This is the first demonstration of a large-scale reorganization of acetylated chromatin induced by a specific factor. PMID:12861021

Miranda: cultura griega, estudios clásicos, relación con Andrés Bello

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Miguel Castillo Didier

2005-12-01

Full Text Available Francisco de Miranda (1750-1816, precursor, herói e mártir da Independência da América Hispânica, estudou a língua grega e reuniu uma vasta biblioteca, com mais de 170 autores gregos. A idéia de liberdade para a américa espanhola surgiu nele em 1781, ligada a sua profunda admiração pela Grécia, na qual nasceu a liberdade. Aí está porque em sua longa viagem através da Europa, em 1786, apesar das ameaças e dos perigos, ele viajou para a Grécia, que gemia sob a dominação otomana. Ele desejava conhecer os lugares onde haviam nascido as idéias de liberdade e democracia, onde um pequeno povo havia vencido um gigantesco império absolutista. Miranda visitou o Pireu, Atenas, Corinto, Salamina, Maratona e depois Esmirna e Constantinopla. Escreveu um jornal muito interessante de sua viagem à Grécia. Em 1792, Miranda serviu na França, quando a Revolução Francesa ainda não tinha abandonado os ideais libertários. Lá, Miranda defendeu os princípios republicanos e a divisão dos poderes, invocando não Montesquieu, mas o exemplo da Grécia antiga. Pedro Grase iniciou com Miranda seu estudo da tradição humanista na América Latina e prossegue com Andrés Bello (1781-1816, o grande sábio que estudou a língua grega na biblioteca de Miranda, em Londres, e que se tornou latinista e helenista. Bello compartilha de sua convicção de que o estudo do latim e do grego e da cultura clássica está na base de toda a cultura sólida.

The natural population of bees of the earth (Melipona beecheii) and their flora in the valley San Andrés

OpenAIRE

Katiuska Ravelo Pimentel; Fernando Ramón Hernández Martínez; Iván Paneque Torres; Luisa Elena Toledo Peña; Hilda Gutiérrez Hernández

2014-01-01

The relationship of the natural population of bees of the earth is evaluated (Melipona beecheii) and its flora in the valley San Andrés, to inclination observations and samplings carried out in the formations studied vegetable. The melliferous plants and their use like tree of the nest of Melipona beecheii were studied for each one of the vegetable formations of the valley San Andrés, the indexes of diversity and their relationship were also analyzed with the values of density of colonies. It...

Distribution of the DAZ gene transcripts in human testis.

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J B Warchoł

2004-07-01

Full Text Available Involvement of variety of genes, especially located on Y chromosome, is critical for the regulation of spermatogenesis. In particular, fertility candidate genes such as deleted in azoospermia (DAZ are believed to have important function in sperm production, since DAZ is frequently deleted in azoospermic and severy oligozoospermic men. The role of the DAZ gene is supported by its exclusive expression in the testis and by its deletion in about 10% of azoospermic and severely oligozoospermic patients. The distribution of DAZ transcripts in seminiferous epithelium of human testis is reported in the present study. The use of Adobe Photoshop and Scion Image softwares allowed for semi-quantitative analysis of in situ RT-PCR (ISRT-PCR results. The intensity of ISRT-PCR product's fluorescence was different within individual seminiferous tubules. It was clearly shown by using the pseudocolour scale and transforming the intensity of the fluorescence into levels of greyscale images. The more intense fluorescence characterised single spermatogonia and those organized in small groups inside separate tubules. The most intense accumulation of DAZ mRNA was observed in spermatogonia.

A Literatura e a Diluição do Autor

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Daniel Marcolino Claudino Sousa

2010-04-01

Full Text Available

Com Dom Quixote, segundo Adorno, tem-se a inauguração do Romance moderno e, por conseqüência, a constituição do autor moderno, um autor não absoluto, desinformado do destino de seus personagens, uma vez que agora o relato romanesco ‘precisa’ de recursos (por vezes, metalingüísticos que passem a evidenciar aspectos de verossimilhança (realismo para se fazer crível ao leitor. E ele o faz, gerando a idéia de níveis de realidade. Procedendo assim, Miguel de Cervantes gera um autor desprovido da autoridade (divina, que era própria dos tempos dos Rapsodos gregos. Busca-se nesse trabalho visualizar, pois a região em que se dá a morte ou a diluição do autor na literatura, este não propriamente gerado pela Metafísica, mas certamente, alimentado por ela, e que é tema de Derrida a Borges. Quando em A escrita de Deus Borges lança mão da idéia de uma alucinada linguagem em que a