WorldWideScience

Sample records for terms topics covered

  1. Braids and coverings selected topics

    CERN Document Server

    Hansen, Vagn Lundsgaard

    1989-01-01

    This book is based on a graduate course taught by the author at the University of Maryland, USA. The lecture notes have been revised and augmented by examples. The work falls into two strands. The first two chapters develop the elementary theory of Artin Braid groups both geometrically and via homotopy theory, and discuss the link between knot theory and the combinatorics of braid groups through Markov's Theorem. The final two chapters give a detailed investigation of polynomial covering maps, which may be viewed as a homomorphism of the fundamental group of the base space into the Artin braid

  2. Design review report, 241-S-102 cover plate review; TOPICAL

    International Nuclear Information System (INIS)

    ADAMS, M.R.

    1998-01-01

    The design for the cover plate and lead plate for shielding on 241-S-102 was reviewed on 10/21/98. All Review Comment Record comments were resolved to the satisfaction of the reviewers. Additional comments were taken during the meeting and were also resolved. A design calculation for the Radiological Design Review Screening was presented as criteria for the use of 1 inch lead plate. The review concluded that the use of 2 inch steel plate and 1 inch lead plate provided the required safety function required by HNF-SD-WM-810-001, 5.3.2.20, Basis for Interim Operation. The design was approved with the incorporated comments as recorded on RCR's and meeting minutes

  3. Evaluation of the LMFBR cover gas source term and synthesis of the associated R and D

    International Nuclear Information System (INIS)

    Balard, F.; Carluec, B.

    1996-01-01

    At the end of the seventies and the beginning of the eighties, there appeared a pressing need of experimental results to assess the LMFBR's safety level. Because of the urgency, analytical studies were not systematically undertaken and maximum credible cover gas instantaneous source terms (radionuclides core release fraction) were got directly from crude out-of-pile experiment interpretations. Two types of studies and mock-ups were undertaken depending on the timescale of the phenomena: instantaneous source terms (corresponding to an unlikely energetic core disruptive accident CDA), and delayed ones (tens of minutes to some hours). The experiments performed in this frame are reviewed in this presentation: 1) instantaneous source term: - FAUST experiments: I, Cs, UO2 source terms (FzK, Germany), - FAST experiments : pool depth influence on non volatile source term (USA), - CARAVELLE experiments: nonvolatile source term in SPX1 geometry (CEA, France); 2) delayed source term: - NALA experiments: I, Cs, Sr, UO2 source term (FzK, Germany), - PAVE experiments: I source term (CEA, France), - NACOWA experiments: cover gas aerosols enrichment in I and Cs (FzK, Germany) - other French experiments in COPACABANA and GULLIVER facilities. The volatile fission products release is tightly bound to sodium evaporation and a large part of the fission products is dissolved in the liquid sodium aerosols present in the cover gas. Thus the knowledge of the amount of aerosol release to the cover gas is important for the evaluation of the source term. The maximum credible cover gas instantaneous source terms deduced from the experiments have led to conservative source terms to be taken into account in safety analysis. Nevertheless modelling attempts of the observed (in-pile or out-of-pile) physico-chemical phenomena have been undertaken for extrapolation to the reactor case. The main topics of this theoretical research are as follows: fission products evaporation in the cover gas (Fz

  4. Nitrate Leaching From Grain Maize After Different Tillage Methods and Long/Short Term Cover Cropping

    DEFF Research Database (Denmark)

    Hansen, Elly Møller

    trial initiated in 1968 on a coarse sandy soil. The previous trial included spring sown crops undersown (with or without) perennial ryegrass (Lolium perenne L.) as cover crop, two N-rates (90 and 120 kg N ha-1) and different tillage methods (shallow tillage and ploughing autumn or spring). With maize......) previous history of long-term cover cropping, ii) soil tillage methods, iii) N rates and iv) present short-term use of cover cropping in maize. Preliminary results from 2009 – 2011 suggest that leaching after a history of cover cropping tended to be higher than after no history of cover cropping......, but the effect was insignificant. The effect of tillage and previous N rates were also insignificant but the present use of cover crops had a small but significant decreasing effect on leaching compared to no cover cropping. The cover crop was well established in both years but grew less vigorously during autumn...

  5. Design surface covers: an approach to long-term waste site stabilization

    International Nuclear Information System (INIS)

    Beedlow, P.A.; Cadwell, L.L.; McShane, M.C.

    1983-02-01

    The wide range of existing environmental conditions, potential contaminants and available cover materials at waste disposal sites necessitates site-specific designing of surface covers for effective long-term erosion resistance. This paper presents a systematic approach to designing surface covers for hazardous waste repositories that can be tailored to conditions at any site. The approach consists of three phases: (1) an assessment, during which the degree of required surface protection (erosion potential) is determined; (2) a preliminary design that integrates surface cover design with the need to minimize transport of contaminants; and (3) a final design, where the cost and effectiveness of the surface cover are determined. 1 figure

  6. Topical nonsteroidal anti-inflammatory drugs for management of osteoarthritis in long-term care patients

    Directory of Open Access Journals (Sweden)

    Argoff CE

    2011-09-01

    Full Text Available Charles E Argoff1, F Michael Gloth2 1Albany Medical College and Comprehensive Pain Center, Albany Medical Center, Albany, NY, USA; 2Johns Hopkins University School of Medicine, Baltimore, MD, USA Abstract: Osteoarthritis is common in patients ≥65 years of age. Although nonsteroidal anti-inflammatory drugs (NSAIDs are often prescribed for osteoarthritis pain, they pose age-related cardiovascular, renal, and gastrointestinal risks. Two topical NSAIDs, diclofenac sodium 1% gel (DSG and diclofenac sodium 1.5% in 45.5% dimethylsulfoxide solution (D-DMSO, are approved in the US for the treatment of osteoarthritis pain. Topical NSAIDs have shown efficacy and safety in knee (DSG, D-DMSO and hand (DSG osteoarthritis. Analyses of data from randomized controlled trials of DSG in hand and knee osteoarthritis demonstrate significant improvement of pain and function in both younger patients (<65 years and older patients (≥65 years and suggest good safety and tolerability. However, long-term safety data in older patients are limited. Topical NSAIDs can ease medication administration and help address barriers to pain management in older patients, such as taking multiple medications and inability to swallow, and are a valuable option for long-term care providers. Keywords: nonsteroidal anti-inflammatory drugs, long-term care, nursing homes, chronic pain, topical analgesics

  7. Vegetation cover, tidal amplitude and land area predict short-term marsh vulnerability in Coastal Louisiana

    Science.gov (United States)

    Schoolmaster, Donald; Stagg, Camille L.; Sharp, Leigh Anne; McGinnis, Tommy S.; Wood, Bernard; Piazza, Sarai

    2018-01-01

    The loss of coastal marshes is a topic of great concern, because these habitats provide tangible ecosystem services and are at risk from sea-level rise and human activities. In recent years, significant effort has gone into understanding and modeling the relationships between the biological and physical factors that contribute to marsh stability. Simulation-based process models suggest that marsh stability is the product of a complex feedback between sediment supply, flooding regime and vegetation response, resulting in elevation gains sufficient to match the combination of relative sea-level rise and losses from erosion. However, there have been few direct, empirical tests of these models, because long-term datasets that have captured sufficient numbers of marsh loss events in the context of a rigorous monitoring program are rare. We use a multi-year data set collected by the Coastwide Reference Monitoring System (CRMS) that includes transitions of monitored vegetation plots to open water to build and test a predictive model of near-term marsh vulnerability. We found that despite the conclusions of previous process models, elevation change had no ability to predict the transition of vegetated marsh to open water. However, we found that the processes that drive elevation change were significant predictors of transitions. Specifically, vegetation cover in prior year, land area in the surrounding 1 km2 (an estimate of marsh fragmentation), and the interaction of tidal amplitude and position in tidal frame were all significant factors predicting marsh loss. This suggests that 1) elevation change is likely better a predictor of marsh loss at time scales longer than we consider in this study and 2) the significant predictive factors affect marsh vulnerability through pathways other than elevation change, such as resistance to erosion. In addition, we found that, while sensitivity of marsh vulnerability to the predictive factors varied spatially across coastal Louisiana

  8. Land use and cover change as an overarching topic in the Dutch National Research Programme on Global Air Pollution and Climate Change : issues for implementation

    NARCIS (Netherlands)

    Fresco, L.O.; Berg, van den M.M.; Zeijl-Rozema, van A.E.

    1996-01-01

    The integration study 'Land Use and Cover Change as an overarching topic in the Dutch National Research Programme on Global Air Pollution and Climate Change (NRP)' aims at identifying research fields in which the NRP can contribute most effectively to the international scientific

  9. Soil Water Improvements with the Long Term Use of a Winter Rye Cover Crop

    Science.gov (United States)

    Basche, A.; Kaspar, T.; Archontoulis, S.; Jaynes, D. B.; Sauer, T. J.; Parkin, T.; Miguez, F.

    2015-12-01

    The Midwestern United States, a region that produces one-third of maize and one-quarter of soybeans globally, is projected to experience increasing rainfall variability with future climate change. One approach to mitigate climate impacts is to utilize crop and soil management practices that enhance soil water storage, reducing the risks of flooding and runoff as well as drought-induced crop water stress. While some research indicates that a winter cover crop in a maize-soybean rotation increases soil water, producers continue to be concerned that water use by cover crops will reduce water for a following cash crop. We analyzed continuous in-field soil moisture measurements over from 2008-2014 at a Central Iowa research site that has included a winter rye cover crop in a maize-soybean rotation for thirteen years. This period of study included years in the top third of wettest years on record (2008, 2010, 2014) as well as years in the bottom third of driest years (2012, 2013). We found the cover crop treatment to have significantly higher soil water storage from 2012-2014 when compared to the no cover crop treatment and in most years greater soil water content later in the growing season when a cover crop was present. We further found that the winter rye cover crop significantly increased the field capacity water content and plant available water compared to the no cover crop treatment. Finally, in 2012 and 2013, we measured maize and soybean biomass every 2-3 weeks and did not see treatment differences in crop growth, leaf area or nitrogen uptake. Final crop yields were not statistically different between the cover and no cover crop treatment in any of the years of this analysis. This research indicates that the long-term use of a winter rye cover crop can improve soil water dynamics without sacrificing cash crop growth.

  10. Role of water balance in the long-term stability of hazardous waste site cover treatments

    International Nuclear Information System (INIS)

    Barnes, F.J.; Rodgers, J.C.; Trujillo, G.

    1986-01-01

    After the 30-year post-closure maintenance period at hazardous waste landfills, long-term stability must be assured without continued intervention. Understanding water balance in the established vegetative cover system is central to predicting such stability. A Los Alamos National Laboratory research project has established a series of experimental cover treatment plots on a closed waste disposal site which will permit the determination of the effects of such critical parameters as soil cover design, leaf area index, and rooting characteristics on water balance under varied conditions. Data from these experiments are being analyzed by water balance modeling and other means. The results show consistent differences in soil moisture storage between soil profiles and between vegetation cover treatments

  11. Low-level radioactive waste source term model development and testing: Topical report

    International Nuclear Information System (INIS)

    Sullivan, T.M.; Kempf, C.R.; Suen, C.J.; Mughabghab, S.M.

    1988-08-01

    The Low-Level Waste Source Term Evaluation Project has the objective to develop a system model capable of predicting radionuclide release rates from a shallow land burial facility. The previous topical report for this project discussed the framework and methodology for developing a system model and divided the problem into four compartments: water flow, container degradation, waste form leaching, and radionuclide transport. Each of these compartments is described by submodels which will be coupled into the system model. From February 1987 to March 1988, computer models have been selected to predict water flow (FEMWATER) and radionuclide transport (FEMWASTE) and separate models have been developed to predict pitting corrosion of steel containers and leaching from porous waste forms contained in corrodible containers. This report discusses each of the models in detail and presents results obtained from applying the models to shallow land burial trenches over a range of expected conditions. 68 refs., 34 figs., 14 tabs

  12. Topical Session on Liabilities identification and long-term management at national level - Topical Session held during the 36. Meeting of the RWMC

    International Nuclear Information System (INIS)

    2003-01-01

    These proceedings cover a topical session that was held at the March 2003 meeting of the Radioactive Waste Management Committee. The topical session focused on liability assessment and management for decommissioning of all types of nuclear installations, including decontamination of historic sites and waste management, as applicable. The presentations covered the current, national situations. The first oral presentation, from Switzerland, set the scene by providing a broad coverage of the relevant issues. The subsequent presentations - five from Member countries and one from the EC - described additional national positions and the evolving EC proposed directives. Each oral presentation was followed by a brief period of Q and As for clarification only. A plenary discussion took place on the ensemble of presentations and a Rapporteur provided a report on points made and lessons learnt. Additionally, written contributions were provided by RWMC delegates from several other countries. These are included in the proceedings as are the papers from the oral sessions, and the Rapporteur's report. These papers are not intended to be exhaustive, but to give an informed glimpse of NEA countries' approaches to liability identification and management in the context of nuclear facilities decommissioning and dismantling

  13. Guidance for disposal of uranium-mill tailings: long-term stabilization of earthen cover materials

    International Nuclear Information System (INIS)

    Voorhees, L.D.; Sale, M.J.; Webb, J.W.; Mulholland, P.J.

    1983-06-01

    The primary hazard associated with uranium-mill tailings is exposure to a radioactive gas, 222 Rn, the concentration of which has been correlated with the occurrence of lung cancer. Previous studies on radon attenuation conclude that the placement of earthen cover materials over the tailings is the most effective technique for reducing radioactive emissions and dispersal of tailings. The success of such a plan, however, depends on long-term protection of these cover materials. 230 Th, which decays to 222 Rn, has a half-life of about 80,000 years. The three major options available for stabilization of uranium-mill tailings are (1) rock cover, (2) soil and revegetation, or (3) a combination of both on different portions of the tailings cover. The optimal choice among these alternatives depends on site-specific characteristics such as climate and local geomorphology and soils, and on design variables such as embankment heights and slopes, modification of upstream drainage, and revegetation practices. Generally, geomorphic evidence suggests that use of soil and vegetation alone will not be adequate to reduce erosion on slopes greater than about 5 0 . For these steeper slopes, riprap will be necessary to maximize the probability of long-term stability. The use of vegetation to control erosion on the flatter portions of the site may be practicable in regions with sufficient rainfall and suitable soil types, but revegetation practices must be carefully evaluated

  14. Natural analogs of the long-term performance of engineered covers

    International Nuclear Information System (INIS)

    Waugh, W.J.; Petersen, K.L.; Link, S.O.; Bjornstad, B.N.; Gee, G.W.

    1994-01-01

    The unprecedented legislative demand that in-situ waste-disposal facilities effectively persist indefinitely requires a performance assessment approach that exceeds standard engineering practices and incorporates possible long-term changes in site hydrology, geology, and ecology. Even in relatively arid regions, over time, buried waste will be vulnerable to transport via rainwater percolation, gas diffusion, erosion, and intrusion by plant roots, burrowing animals, and humans. Standard models and field tests of engineered covers designed to impede these pathways implicitly and erroneously assume that initial conditions of many key determinants will persist indefinitely. Evidence from natural, archaeological, and engineered analogs is needed (1) to identify and understand emergent system attributes that cannot be captured with computer models or short-term experiments, and (2) to develop modeling and field tests that reasonably bound possible future changes in waste-site environments. Analogs of local responses to future global climate change exist as proxy ecological and archaeological records of similar paleoclimates. Future pedogenic influences can be inferred form measurements of key soil properties in natural and archaeological soil profiles analogous to engineered covers. Many cover designs depend on water extraction by plants. Influences of vegetation change can be inferred by measuring water extraction parameters in plant communities representing successional chronosequences. Habitats similar to those created on waste sites provide evidence of the potential for biological intrusion. Recent and ancient man-made structures provide evidence of the future stability of waste-site covers and of features that may discourage human intrusion. 108 refs., 4 figs

  15. Topics to be covered in safety analysis reports for nuclear power plants with pressurized water reactors or boiling water reactors in the F.R.G

    International Nuclear Information System (INIS)

    Kohler, H.A.G.

    1977-01-01

    This manual aims at defining the standards to be used in Safety Analysis Reports for Nuclear Power Plants with Pressurized Water Reactors or Boiling Water Reactors in the Federal Republic of Germany. The topics to be covered are: Information about the site (geographic situation, settlement, industrial and military facilities, transport and communications, meteorological conditions, geological, hydrological and seismic conditions, radiological background), description of the power plant (building structures, safety vessel, reactor core, cooling system, ventilation systems, steam power plant, electrical facilities, systems for measurement and control), indication of operation (commissioning, operation, safety measures, radiation monitoring, organization), incident analysis (reactivity incidents, loss-of-coolant incidents, external impacts). (HP) [de

  16. Ocular surface evaluation in eyes with chronic glaucoma on long term topical antiglaucoma therapy

    Directory of Open Access Journals (Sweden)

    Manu Saini

    2017-06-01

    Full Text Available AIM: To evaluate ocular surface changes and its correlation with the central corneal subbasal nerve fibre layer in chronic glaucoma patients. METHODS: A prospective comparative study of ocular surface evaluation was performed in 50 eyes of 25 patients using two or more antiglaucoma medications for at least 6mo and 50 eyes of 25 normal subjects without any ocular problems as controls. The study parameters evaluated included visual acuity, intraocular pressure, ocular surface evaluation parameters [fluorescein break-up time (FTBUT, Schirmer’s I test, ocular surface staining scores and ocular surface disease index score (OSDI], central corneal sensation (Cochet Bonnett aesthesiometer, central subbasal nerve fiber layer density (SBNFLD by confocal microscopy. RESULTS: The mean values in the glaucoma cases and control groups respectively were as follows: OSDI score (35.89±16.07/6.02±3.84; P=0.001, Schirmer’s I test score (7.63±2.64 mm/12.86±1.93 mm; P=0.001, FTBUT (9.44±2.76s/11.8±1.88s; P=0.001, corneal (5.7±2.33/ 1.1±0.58; P=0.001 and conjunctival staining score (5.06±1.94/0.84±0.46; P=0.001, corneal sensitivity (4.68±0.44/5.07±0.37; P=0.076, mean subbasal nerve fiber number (3.58±0.99/5.40±1.70; P=0.001, SBNFL length (1101.44±287.56 μm/1963.70±562.56 μm; P=0.001 and density (6883.94±1798.03 μm/mm2/12 273.15±3516.04 μm/mm2; P=0.001. Dry eye severity of level 2 and 3 was seen in 66% of glaucoma group. Corneal (R²=0.86 and conjunctival staining (R²=0.71 and OSDI score (R²=0.67 showed statistically significant negative correlation with central corneal SBNFLD while FTBUT (R²=0.84, corneal sensitivity (R²=0.52 showed positive correlation to central corneal SBNFLD in the long term topical antiglaucoma medication group. CONCLUSION: Ocular surface changes and antiglaucoma therapy induced dry eye is found to be associated with decreased SBNFLD in eyes on long term topical antiglaucoma medications.

  17. Predicting long-term moisture contents of earthen covers at uranium mill tailings sites

    International Nuclear Information System (INIS)

    Gee, G.W.; Nielson, K.K.; Rogers, V.C.

    1984-09-01

    The three methods for long-term moisture prediction covered in this report are: estimates from water retention (permanent wilting point) data, correlation with climate and soil type, and detailed model simulation. The test results have shown: soils vary greatly in residual moisture. Expected long-term moisture saturation ratios (based on generalized soil characteristics) range from 0.2 to 0.8 for soils ranging in texture from sand to clay, respectively. These values hold for noncompacted field soils. Measured radon diffusion coefficients for soils at 15-bar water contents ranged from 5.0E-2 cm 2 /s to 5.0E-3 cm 2 /s for sands and clays, respectively, at typical field densities. In contrast, fine-textured pit-run earthen materials, subjected to optimum compaction (>85% Proctor density) and dried to the 15-bar water content, ranged from 0.7 to 0.9 moisture saturation. Compacted pit-run soils at these moisture contents exhibited radon diffusion coefficients as low as 3.0E-4 cm 2 /s. The residual moisture saturation for cover soils is not known since no engineered barrier has been in place for more than a few years. A comparison of methods for predicting moisture saturation indicates that model simulations are useful for predicting effects of climatic changes on residual soil moisture, but that long-term moisture also can be predicted with some degree of confidence using generalized soil properties or empirical correlations based both on soils and climatic information. The optimal soil cover design will likely include more than one layer of soil. A two-layer system using a thick (1-m minimum) plant root zone of uncompacted soil placed over a moistened, tightly compacted fine-textured soil is recommended. This design concept has been tested successfully at the Grand Junction, Colorado, tailings piles

  18. Meshable: searching PubMed abstracts by utilizing MeSH and MeSH-derived topical terms.

    Science.gov (United States)

    Kim, Sun; Yeganova, Lana; Wilbur, W John

    2016-10-01

    Medical Subject Headings (MeSH(®)) is a controlled vocabulary for indexing and searching biomedical literature. MeSH terms and subheadings are organized in a hierarchical structure and are used to indicate the topics of an article. Biologists can use either MeSH terms as queries or the MeSH interface provided in PubMed(®) for searching PubMed abstracts. However, these are rarely used, and there is no convenient way to link standardized MeSH terms to user queries. Here, we introduce a web interface which allows users to enter queries to find MeSH terms closely related to the queries. Our method relies on co-occurrence of text words and MeSH terms to find keywords that are related to each MeSH term. A query is then matched with the keywords for MeSH terms, and candidate MeSH terms are ranked based on their relatedness to the query. The experimental results show that our method achieves the best performance among several term extraction approaches in terms of topic coherence. Moreover, the interface can be effectively used to find full names of abbreviations and to disambiguate user queries. https://www.ncbi.nlm.nih.gov/IRET/MESHABLE/ CONTACT: sun.kim@nih.gov Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.

  19. Multi-Temporal Land Cover Classification with Long Short-Term Memory Neural Networks

    Science.gov (United States)

    Rußwurm, M.; Körner, M.

    2017-05-01

    Land cover classification (LCC) is a central and wide field of research in earth observation and has already put forth a variety of classification techniques. Many approaches are based on classification techniques considering observation at certain points in time. However, some land cover classes, such as crops, change their spectral characteristics due to environmental influences and can thus not be monitored effectively with classical mono-temporal approaches. Nevertheless, these temporal observations should be utilized to benefit the classification process. After extensive research has been conducted on modeling temporal dynamics by spectro-temporal profiles using vegetation indices, we propose a deep learning approach to utilize these temporal characteristics for classification tasks. In this work, we show how long short-term memory (LSTM) neural networks can be employed for crop identification purposes with SENTINEL 2A observations from large study areas and label information provided by local authorities. We compare these temporal neural network models, i.e., LSTM and recurrent neural network (RNN), with a classical non-temporal convolutional neural network (CNN) model and an additional support vector machine (SVM) baseline. With our rather straightforward LSTM variant, we exceeded state-of-the-art classification performance, thus opening promising potential for further research.

  20. MULTI-TEMPORAL LAND COVER CLASSIFICATION WITH LONG SHORT-TERM MEMORY NEURAL NETWORKS

    Directory of Open Access Journals (Sweden)

    M. Rußwurm

    2017-05-01

    Full Text Available Land cover classification (LCC is a central and wide field of research in earth observation and has already put forth a variety of classification techniques. Many approaches are based on classification techniques considering observation at certain points in time. However, some land cover classes, such as crops, change their spectral characteristics due to environmental influences and can thus not be monitored effectively with classical mono-temporal approaches. Nevertheless, these temporal observations should be utilized to benefit the classification process. After extensive research has been conducted on modeling temporal dynamics by spectro-temporal profiles using vegetation indices, we propose a deep learning approach to utilize these temporal characteristics for classification tasks. In this work, we show how long short-term memory (LSTM neural networks can be employed for crop identification purposes with SENTINEL 2A observations from large study areas and label information provided by local authorities. We compare these temporal neural network models, i.e., LSTM and recurrent neural network (RNN, with a classical non-temporal convolutional neural network (CNN model and an additional support vector machine (SVM baseline. With our rather straightforward LSTM variant, we exceeded state-of-the-art classification performance, thus opening promising potential for further research.

  1. Prediction of long-term erosion from landfill covers in the southwest

    International Nuclear Information System (INIS)

    Anderson, C.E.; Stormont, J.C.

    1997-01-01

    Erosion is a primary stressor of landfill covers, especially for climates with high intensity storms and low native plant density. Rills and gullies formed by discrete events can damage barrier layers and induce failure. Geomorphologic, empirical and physical modeling procedures are available to provide estimates of surface erosion, but numerical modeling requires accurate representation of the severe rainfall events that generate erosion. The National Weather Service precipitation frequency data and estimates of 5, 10, 15, 30 and 60-minute intensity can be statistically combined in a numerical model to obtain long-term erosion estimates. Physically based numerical models using the KINEROS and AHYMO programs have been utilized to predict the erosion from a southwestern landfill or waste containment site with 0.03, 0.05 and 0.08 meter per meter surface slopes. Results of AHYMO modeling were within 15 percent of average annual values computed with the empirical Universal Soil Loss Equation. However, the estimation of rill and gully formation that primarily degrades cover systems requires quantifying single events. For Southwestern conditions, a single 10-year storm can produce erosion quantifies equal to three times the average annual erosion and a 100-year storm can produce five times the average annual erosion

  2. Long-term patency of experimental magnetic compression gastroenteric anastomoses achieved with covered stents.

    Science.gov (United States)

    Cope, C; Ginsberg, G G

    2001-06-01

    Our aim was to evaluate the efficacy of a prototype "YO-YO"-shaped covered stent for keeping experimental magnetic compression gastroenteric fistulas patent for 6 months. Magnets were introduced perorally with endoscopic and fluoroscopic guidance and were mated across the gastric and jejunal walls of 5 dogs. After a mean of 5.5 days a 12-mm diameter YO-YO stent was placed perorally in the resulting fistula. The gastroenteric anastomosis (GEA) with stent was observed endoscopically and gastrographically at 1- to 2-month intervals. There was no morbidity and there were no significant weight changes. The GEA was widely patent at necropsy at 6 months (n = 4); partial membrane separation occurred at 5 months in the fifth dog. There was minor breakage of the stent prongs in 2 animals. Peroral creation of a stented magnetic compression GEA is safe and provides long-term patency. This technique may be potentially useful for managing gastric outlet obstruction caused by malignancy.

  3. 2 CFR 176.160 - Award term-Required Use of American Iron, Steel, and Manufactured Goods (covered under...

    Science.gov (United States)

    2010-01-01

    ... award term and condition— Designated country—(1) A World Trade Organization Government Procurement..., Steel, and Manufactured Goods (covered under International Agreements)-Section 1605 of the American... Award term—Required Use of American Iron, Steel, and Manufactured Goods (covered under International...

  4. Effects of long-term repeated topical fluoride applications and adhesion promoter on shear bond strengths of orthodontic brackets

    Science.gov (United States)

    Endo, Toshiya; Ishida, Rieko; Komatsuzaki, Akira; Sanpei, Shinya; Tanaka, Satoshi; Sekimoto, Tsuneo

    2014-01-01

    Objective: The purpose of this study was to assess the effects of long-term repeated topical application of fluoride before bonding and an adhesion promoter on the bond strength of orthodontic brackets. Materials and Methods: A total of 76 bovine incisors were collected and divided equally into four groups. In group 1, the brackets were bonded without topical fluoride application or adhesion promoter. In group 2, before bonding, the adhesion promoter was applied to nonfluoridated enamel. In group 3, the brackets were bonded without the application of the adhesion promoter to enamel, which had undergone long-term repeated topical fluoride treatments. Teeth in group 4 received the long-term repeated topical applications of fluoride, and the brackets were bonded using the adhesion promoter. All the brackets were bonded using BeautyOrtho Bond self-etching adhesive. The shear bond strength was measured and the bond failure modes were evaluated with the use of the adhesive remnant index (ARI) after debonding. Results: The mean shear bond strength was significantly lower in group 3 than in groups 1, 2, and 4, and there were no significant differences between the groups except for group 3. There were significant differences in the distribution of ARI scores between groups 2 and 3, and between groups 3 and 4. Conclusions: The adhesion promoter can recover the bond strength reduced by the long-term repeated topical applications of fluoride to the prefluoridation level and had a significantly great amount of adhesives left on either fluoridated or nonfluoridated enamel. PMID:25512720

  5. Long Term Follow-up of a Transjugular Intrahepatic Portosystemic Shunt: A Comparison of Covered and Uncovered Stents

    Energy Technology Data Exchange (ETDEWEB)

    Joo, Seung Moon; Park, Jae Hyung; Kim, Hyo Cheol; Jae, Hwan Jun; Chung, Jin Wook [Seoul National University Hospital, Seoul (Korea, Republic of)

    2009-01-15

    To evaluate the long term patency of transjugular intrahepatic portosystemic shunts (TIPS) and to compare the patency rate of covered and uncovered stents in TIPS. The study population included 78 patients with portal hypertension that underwent TIPS between January 1999 and July 2007 at our institution using uncovered stents in 53 patients and covered stents in 25 patients. The primary and secondary patency rates of TIPS were estimated to compare the uncovered and covered stent groups. The primary and secondary patency rates of the TIPS patients were found to be 83.9% and 93.9% at the 6 month follow-up and 73.5% and 88.5% at the12 month follow-up for uncovered and covered stents, respectively. A breakdown patency rates for the 12 month follow-up revealed that the primary patency rates were 76.6% and 66.3% for uncovered and covered stents, respectively; whereas, the secondary patency rates were 94.3% and 73.8% for the uncovered and covered stents, respectively. A comparative analysis did not provide evidence to suggest that a difference exists between the patency rates of the uncovered and covered stent groups (p>0.05). No significant difference was found between the patency rates of the uncovered and covered stent groups. A follow-up to this study would be a more thorough randomized evaluation of the different types of covered stents to compare long-term patency rates.

  6. Long-term monitoring of stream bank stability under different vegetation cover

    Science.gov (United States)

    Krzeminska, Dominika; Skaalsveen, Kamilla; Kerkhof, Tjibbe

    2017-04-01

    Vegetated buffer zones are common environmental measures in many countries, including Norway. The presence of riparian vegetation on stream banks not only provides ecological benefits but also influence bank slope stability, through several complex interactions between riparian vegetation and hydro - mechanical processes. The hydrological processes associated with slope stability are complex and yet difficult to quantify, especially because their transient effects (e.g. changes throughout the vegetation life cycle). Additionally, there is very limited amount of field scale research focusing on investigation of coupled hydrological and mechanical influence of vegetation on stream bank behavior, accounting for both seasonal time scale and different vegetation type, and none dedicated to marine clay soils (typically soil for Norway). In order to fill this gap we established continues, long term hydrogeological monitoring o selected cross - section within stream bank, covered with different types of vegetation, typical for Norwegian agriculture areas (grass, shrubs, and trees). The monitoring involves methods such as spatial and temporal monitoring of soil moisture conditions, ground water level and fluctuation of water level in the stream. Herein we will present first 10 months of monitoring data: observed hydrological trends and differences between three cross - sections. Moreover, we will present first modelling exercises that aims to estimate stream banks stability with accounting on presence of different vegetation types using BSTEM and HYDRUS models. With this presentation, we would like to stimulate the discussion and get feedback that could help us to improve both, our experimental set up and analysis approach.

  7. Effects of long-term elevated temperature on covering, sheltering and righting behaviors of the sea urchin Strongylocentrotus intermedius

    Science.gov (United States)

    Zhang, Lisheng; Zhang, Lingling; Shi, Dongtao; Wei, Jing; Chang, Yaqing

    2017-01-01

    Increases in ocean temperature due to climate change are predicted to change the behaviors of marine invertebrates. Altered behaviors of keystone ecosystem engineers such as echinoderms will have consequences for the fitness of individuals, which are expected to flow on to the local ecosystem. Relatively few studies have investigated the behavioral responses of echinoderms to long-term elevated temperature. We investigated the effects of exposure to long-term (∼31 weeks) elevated temperature (∼3 °C above the ambient water temperature) on covering, sheltering and righting behaviors of the sea urchin Strongylocentrotus intermedius. Long-term elevated temperature showed different effects on the three behaviors. It significantly decreased covering behavior, including both covering behavior reaction (time to first covering) and ability (number of covered sea urchins and number of shells used for covering). Conversely, exposure to long-term elevated temperature significantly increased sheltering behavior. Righting response in S. intermedius was not significantly different between temperature treatments. The results provide new information into behavioral responses of echinoderms to ocean warming. PMID:28348933

  8. Evaluation of retinal nerve fiber layer thickness in vernal keratoconjunctivitis patients under long-term topical corticosteroid therapy.

    Science.gov (United States)

    Cingu, Abdullah Kursat; Cinar, Yasin; Turkcu, Fatih Mehmet; Sahinoglu-Keskek, Nedime; Sahin, Alparslan; Sahin, Muhammed; Yuksel, Harun; Caca, Ihsan

    2014-09-01

    The aim of this study was to evaluate the retinal nerve fiber layer (RNFL) thickness in vernal keratoconjunctivitis (VKC) patients who were under long-term topical corticosteroid therapy. Thirty-six eyes of 36 VKC patients with clear cornea and normal videokeratography and 40 eyes of 40 age- and gender-matched normal children were included in the study. Clinical and demographic characteristics of the patients were noted and detailed ophthalmological examination was performed. Visual acuity (VA), spherical equivalent (SE), axial length (AL) and RNFL thickness measurements were compared between the groups. To correct ocular magnification effect on RNFL, we used Littmann's formula. All VKC patients had history of topical corticosteroid use and the mean duration of the topical corticosteroid use was 23.8 ± 9.09 months. There was no significant difference between the groups in terms of intraocular pressure (IOP). VKC group had significantly worse VA, greater SE and AL and thinner mean global, superior and inferior RNFL thickness. There were significant negative correlations between the duration of topical corticosteroid use and the mean global, superior and temporal RNFL thickness in VKC group. After correction of magnification effect, VKC group still had thinner mean global, superior and inferior RNFL thickness, and significant difference between the groups in inferior RNFL thickness did not disappear. Significant RNFL thickness difference between the groups suggests a possible effect of long-term corticosteroid use in VKC patients. Because visual field (VF) analysis in pediatric patients is difficult to perform and IOP may be illusive, RNFL thickness measurements in addition to routine examinations in VKC patients may help clinicians in their practice.

  9. Selected source term topics. Report to CSNI by an OECD/NEA Group of experts

    International Nuclear Information System (INIS)

    1987-04-01

    CSNI Report 136 summarizes the results of the work performed by the Group of Experts on the Source Term and Environmental Consequences (PWG4) during the period extending from 1983 and 1986. This report is complementary to Part 1, 'Technical Status of the Source Term' of CSNI Report 135, 'Report to CSNI on Source Term Assessment, Containment atmosphere control systems, and accident consequences'; it considers in detail a number of very specific issues thought to be important in the source term area. It consists of: an executive summary (prepared by the Chairman of the Group), a section on conclusions and recommendations, and five technical chapters (fission product chemistry in the primary circuit of a LWR during severe accidents; resuspension/re-entrainment of aerosols in LWRs following a meltdown accident; iodine chemistry under severe accident conditions; effects of combustion, steam explosions and pressurized melt ejection on fission product behaviour; radionuclide removal by pool scrubbing), a technical annex and two appendices

  10. Google Trends terms reporting rhinitis and related topics differ in European countries.

    Science.gov (United States)

    Bousquet, J; Agache, I; Anto, J M; Bergmann, K C; Bachert, C; Annesi-Maesano, I; Bousquet, P J; D'Amato, G; Demoly, P; De Vries, G; Eller, E; Fokkens, W J; Fonseca, J; Haahtela, T; Hellings, P W; Just, J; Keil, T; Klimek, L; Kuna, P; Lodrup Carlsen, K C; Mösges, R; Murray, R; Nekam, K; Onorato, G; Papadopoulos, N G; Samolinski, B; Schmid-Grendelmeier, P; Thibaudon, M; Tomazic, P; Triggiani, M; Valiulis, A; Valovirta, E; Van Eerd, M; Wickman, M; Zuberbier, T; Sheikh, A

    2017-08-01

    Google Trends (GT) searches trends of specific queries in Google and reflects the real-life epidemiology of allergic rhinitis. We compared Google Trends terms related to allergy and rhinitis in all European Union countries, Norway and Switzerland from 1 January 2011 to 20 December 2016. The aim was to assess whether the same terms could be used to report the seasonal variations of allergic diseases. Using the Google Trend 5-year graph, an annual and clear seasonality of queries was found in all countries apart from Cyprus, Estonia, Latvia, Lithuania and Malta. Different terms were found to demonstrate seasonality depending on the country - namely 'hay fever', 'allergy' and 'pollen' - showing cultural differences. A single set of terms cannot be used across all European countries, but allergy seasonality can be compared across Europe providing the above three terms are used. Using longitudinal data in different countries and multiple terms, we identified an awareness-related spike of searches (December 2016). © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  11. Use of Long-Term Lysimeter Data in Support of Shallow Land Waste Disposal Cover Design

    International Nuclear Information System (INIS)

    Desotell, L.T.; Hudson, D.B.; Yucel, V.; Carilli, J.T.

    2006-01-01

    Water balance studies using two precision weighing lysimeters have been conducted at the Nevada Test Site in support of low-level radioactive waste disposal since 1994. The lysimeters are located in northern Frenchman Flat approximately 400 meters (m) from the southwest corner of the Area 5 Radioactive Waste Management Site. Frenchman Flat is in the northern Mojave Desert and has an average annual precipitation of 125 millimeters (mm). Each lysimeter consists of a 2 m by 4 m by 2 m deep steel tank filled with native alluvium, supported on a sensitive scale. The scale is instrumented with an electronic load-cell and data-logger for continuous measurement of total soil water storage with a precision of approximately ±800 grams or ±0.1 mm of soil water storage. Data-loggers are linked to cell phone modems for remote data acquisition. One lysimeter is vegetated with native creosote bush, four wing salt bush, and annual grass at the approximate density of the surrounding landscape while the other is maintained as bare soil. Since no drainage has been observed from the bottom of the lysimeters and run-on/run-off is precluded, the change in soil-water storage is equal to precipitation minus evaporation/evapotranspiration. After equilibration, the bare lysimeter contains approximately 20.2 centimeters (cm) of water (10.1 % volumetric water content) and the vegetated lysimeter contains approximately 11.6 cm of water (5.8 % volumetric water content). The finite difference code UNSAT-H was used to simulate the continuous water balance of the lysimeters. Calibrated one-dimensional model simulations were generally in agreement with field data. 30-year model simulations were conducted to evaluate long-term potential transport of radionuclides via the soil water migration pathway. A 30-year climate record was generated by repeating the existing data record. Simulations indicate a 2 m thick closure cover, in conjunction with native vegetation, will essentially eliminate drainage

  12. No antiinflammatory effect of short-term topical and subcutaneous administration of local anesthetics on postburn inflammation

    DEFF Research Database (Denmark)

    Møiniche, S; Dahl, J B; Brennum, J

    1993-01-01

    , development of blister and ulcerations, or the intensity of inflammation after burn injury between the control legs and EMLA- or bupivacaine-treated legs, respectively. CONCLUSION. No antiinflammatory effect of short-term preinjury and postinjury topical 5% EMLA or subcutaneous 0.5% bupivacaine could...... and left calves with a 15 x 25 mm rectangular thermode. Eight subjects had topical 5% EMLA applied before and after burn injury, and another eight subjects were administered subcutaneous 0.5% bupivacaine infiltration before burn injury on the right or left leg. No treatment was applied to the contralateral...... leg in either group because this served as the control. The dermal response after burn injury in test areas with EMLA or bupivacaine and without treatment was compared 24 hours, 72 hours, 168 hours, and 14 days after burn injury. RESULTS. No significant difference was found in the area of flare...

  13. Google Trends terms reporting rhinitis and related topics differ in European countries

    DEFF Research Database (Denmark)

    Bousquet, J.; Agache, I; Anto, J M

    2017-01-01

    Google Trends (GT) searches trends of specific queries in Google and reflects the real-life epidemiology of allergic rhinitis. We compared Google Trends terms related to allergy and rhinitis in all European Union countries, Norway and Switzerland from 1 January 2011 to 20 December 2016. The aim w...

  14. Topical Modulation of the Burn Wound Inflammatory Response to Improve Short and Long Term Outcomes

    Science.gov (United States)

    2017-10-01

    paradigm shift in the clinical treatment of challenging dermal injuries. 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT...significant morbidity, disabling loss of function, extended difficult recovery times, dramatically affecting the patient’s quality of life physically

  15. Coupled Environmental Processes and Long-term Performance of Landfill Covers in the northern Mojave Desert

    Energy Technology Data Exchange (ETDEWEB)

    David Shafer; Michael Young; Stephen Zitzer; Eric McDonald; Todd Caldwell

    2004-05-12

    Evapotransiration (ET) covers have gained widespread acceptance as a closure feature for waste disposal sites, particularly in the arid and semi-arid regions of the southwestern U.S. But as landforms, ET covers are subject to change over time because of processes such as pedogenesis, hydrologic processes, vegetation establishment and change, and biological processes. To better understand the effects of coupled process changes to ET covers, a series of four primary analog sites in Yucca Flat on the Nevada Test Site, along with measurements and observations from other locations in the Mojave Desert, were selected to evaluate changes in ET covers over time. The analog sites, of varying ages, were selected to address changes in the early post-institutional control period, the 1,000-year compliance period for disposal of low-level and mixed low-level waste, and the 10,000-year compliance period for transuranic waste sites.

  16. Coupled Environmental Processes and Long-term Performance of Landfill Covers in the northern Mojave Desert

    International Nuclear Information System (INIS)

    David Shafer; Michael Young; Stephen Zitzer; Eric McDonald; Todd Caldwell

    2004-01-01

    Evapotransiration (ET) covers have gained widespread acceptance as a closure feature for waste disposal sites, particularly in the arid and semi-arid regions of the southwestern U.S. But as landforms, ET covers are subject to change over time because of processes such as pedogenesis, hydrologic processes, vegetation establishment and change, and biological processes. To better understand the effects of coupled process changes to ET covers, a series of four primary analog sites in Yucca Flat on the Nevada Test Site, along with measurements and observations from other locations in the Mojave Desert, were selected to evaluate changes in ET covers over time. The analog sites, of varying ages, were selected to address changes in the early post-institutional control period, the 1,000-year compliance period for disposal of low-level and mixed low-level waste, and the 10,000-year compliance period for transuranic waste sites

  17. Human-competitive automatic topic indexing

    CERN Document Server

    Medelyan, Olena

    2009-01-01

    Topic indexing is the task of identifying the main topics covered by a document. These are useful for many purposes: as subject headings in libraries, as keywords in academic publications and as tags on the web. Knowing a document’s topics helps people judge its relevance quickly. However, assigning topics manually is labor intensive. This thesis shows how to generate them automatically in a way that competes with human performance. Three kinds of indexing are investigated: term assignment, a task commonly performed by librarians, who select topics from a controlled vocabulary; tagging, a popular activity of web users, who choose topics freely; and a new method of keyphrase extraction, where topics are equated to Wikipedia article names. A general two-stage algorithm is introduced that first selects candidate topics and then ranks them by significance based on their properties. These properties draw on statistical, semantic, domain-specific and encyclopedic knowledge. They are combined using a machine learn...

  18. Earth observation data for assessment of nationwide land cover and long-term deforestation in Afghanistan

    Science.gov (United States)

    Sudhakar Reddy, C.; Saranya, K. R. L.

    2017-08-01

    This study has generated a national level spatial database of land cover and changes in forest cover of Afghanistan for the 1975-1990, 1990-2005 and 2005-2014 periods. Using these results we have analysed the annual deforestation rates, spatial changes in forests, forest types and fragmentation classes over a period of 1975 to 2014 in Afghanistan. The land cover map of 2014 provides distribution of forest (dry evergreen, moist temperate, dry temperate, pine, sub alpine) and non-forest (grassland, scrub, agriculture, wetlands, barren land, snow and settlements) in Afghanistan. The largest land cover, barren land, contributes to 56% of geographical area of country. Forest is distributed mostly in eastern Afghanistan and constitutes an area of 1.02% of geographical area in 2014. The annual deforestation rate in Afghanistan's forests for the period from 1975 to 1990 estimated as 0.06% which was declined significantly from 2005 to 2014. The predominant forest type in Afghanistan is moist temperate which shows loss of 80 km2 of area during the last four decades of the study period. At national level, the percentage of large core forest area was calculated as 52.20% in 2014.

  19. Long term changes in forest cover and land use of Similipal ...

    Indian Academy of Sciences (India)

    K R L Saranya and C Sudhakar Reddy. ∗. Forestry & Ecology Group, National Remote Sensing Centre, ISRO, Balanagar, Hyderabad 500 037, India. ∗. Corresponding author. e-mail: drsudhakarreddy@gmail.com. The spatial changes in forest cover of Similipal biosphere reserve, Odisha, India over eight decades (1930–.

  20. JST Thesaurus Headwords and Synonyms: 辞書(as Topic) [MeCab user dictionary for science technology term[Archive

    Lifescience Database Archive (English)

    Full Text Available MeCab user dictionary for science technology term 辞書(as Topic) 名詞 一般 * * * * 辞書 ジショ ジショ Thesaurus2015 200906028477984205 C BA01 UNKNOWN_2 辞書 ( a s Topic )

  1. Short-term contributions of cover crop surface residue return to soil carbon and nitrogen contents in temperate Australia.

    Science.gov (United States)

    Zhou, Xiaoqi; Wu, Hanwen; Li, Guangdi; Chen, Chengrong

    2016-11-01

    Cover crop species are usually grown to control weeds. After cover crop harvest, crop residue is applied on the ground to improve soil fertility and crop productivity. Little information is available about quantifying the contributions of cover crop application to soil total carbon (C) and nitrogen (N) contents in temperate Australia. Here, we selected eight cover crop treatments, including two legume crops (vetch and field pea), four non-legume crops (rye, wheat, Saia oat, and Indian mustard), a mixture of rye and vetch, and a nil-crop control in temperate Australia to calculate the contributions of cover crops (crop growth + residue decomposition) to soil C and N contents. Cover crops were sown in May 2009 (autumn). After harvest, the crop residue was placed on the soil surface in October 2009. Soil and crop samples were collected in October 2009 after harvest and in May 2010 after 8 months of residue decomposition. We examined cover crop residue biomass, soil and crop total C and N contents, and soil microbial biomass C and N contents. The results showed that cover crop application increased the mean soil total C by 187-253 kg ha -1 and the mean soil total N by 16.3-19.1 kg ha -1 relative to the nil-crop treatment, except for the mixture treatment, which had similar total C and N contents to the nil-crop control. Cover crop application increased the mean soil microbial biomass C by 15.5-20.9 kg ha -1 and the mean soil microbial biomass N by 4.5-10.2 kg ha -1 . We calculated the apparent percentage of soil total C derived from cover crop residue C losses and found that legume crops accounted for 10.6-13.9 %, whereas non-legume crops accounted for 16.4-18.4 % except for the mixture treatment (0.2 %). Overall, short-term cover crop application increased soil total C and N contents and microbial biomass C and N contents, which might help reduce N fertilizer use and improve sustainable agricultural development.

  2. Improving long term resistance of uranium mill tailings covers to hydrologic stress using RIPRAP: a preliminary assessment

    International Nuclear Information System (INIS)

    Walters, W.H.; Skaggs, R.L.

    1980-01-01

    The long term effectiveness of riprap to protect uranium mill tailings repositories against erosion by flowing water is currently being evaluated by Pacific Northwest Laboratory for the US Nuclear Regulatory Commission. The investigation is part of a comprehensive study to determine technically justified and cost effective alternatives for armoring of radon suppression covers. As a protective cover, riprap appears to be one of the most reliable methods because of its proven durability to resist channel bed scour around bridge piers and erosion of river banks. Damage to radon suppression covers by water could occur under similar circumstances where the erosion would be due to overland flow or a large flood event. The principal mechanisms of soil erosion by water are discussed with respect to earth surfaces of mounted or flat geometries. Since long time periods on the order of one thousand years may be involved, any riprap design procedure should consider allowances for partial failures of the cover. Design procedures are summarized and both advantages and disadvantages are discussed. Problems that may occur over long term storage of mill tailings are evaluated in order to put the use of riprap in proper perspective

  3. Land-use poverty traps identified in shifting cultivation systems shape long-term tropical forest cover

    Science.gov (United States)

    Coomes, Oliver T.; Takasaki, Yoshito; Rhemtulla, Jeanine M.

    2011-01-01

    In this article we illustrate how fine-grained longitudinal analyses of land holding and land use among forest peasant households in an Amazonian village can enrich our understanding of the poverty/land cover nexus. We examine the dynamic links in shifting cultivation systems among asset poverty, land use, and land cover in a community where poverty is persistent and primary forests have been replaced over time—with community enclosure—by secondary forests (i.e., fallows), orchards, and crop land. Land cover change is assessed using aerial photographs/satellite imagery from 1965 to 2007. Household and plot level data are used to track land holding, portfolios, and use as well as land cover over the past 30 y, with particular attention to forest status (type and age). Our analyses find evidence for two important types of “land-use” poverty traps—a “subsistence crop” trap and a “short fallow” trap—and indicate that the initial conditions of land holding by forest peasants have long-term effects on future forest cover and household welfare. These findings suggest a new mechanism driving poverty traps: insufficient initial land holdings induce land use patterns that trap households in low agricultural productivity. Path dependency in the evolution of household land portfolios and land use strategies strongly influences not only the wellbeing of forest people but also the dynamics of tropical deforestation and secondary forest regrowth. PMID:21873179

  4. Development of a Risk-Based Probabilistic Performance-Assessment Method for Long-Term Cover Systems - 2nd Edition

    International Nuclear Information System (INIS)

    HO, CLIFFORD K.; ARNOLD, BILL W.; COCHRAN, JOHN R.; TAIRA, RANDAL Y.

    2002-01-01

    A probabilistic, risk-based performance-assessment methodology has been developed to assist designers, regulators, and stakeholders in the selection, design, and monitoring of long-term covers for contaminated subsurface sites. This report describes the method, the software tools that were developed, and an example that illustrates the probabilistic performance-assessment method using a repository site in Monticello, Utah. At the Monticello site, a long-term cover system is being used to isolate long-lived uranium mill tailings from the biosphere. Computer models were developed to simulate relevant features, events, and processes that include water flux through the cover, source-term release, vadose-zone transport, saturated-zone transport, gas transport, and exposure pathways. The component models were then integrated into a total-system performance-assessment model, and uncertainty distributions of important input parameters were constructed and sampled in a stochastic Monte Carlo analysis. Multiple realizations were simulated using the integrated model to produce cumulative distribution functions of the performance metrics, which were used to assess cover performance for both present- and long-term future conditions. Performance metrics for this study included the water percolation reaching the uranium mill tailings, radon gas flux at the surface, groundwater concentrations, and dose. Results from uncertainty analyses, sensitivity analyses, and alternative design comparisons are presented for each of the performance metrics. The benefits from this methodology include a quantification of uncertainty, the identification of parameters most important to performance (to prioritize site characterization and monitoring activities), and the ability to compare alternative designs using probabilistic evaluations of performance (for cost savings)

  5. Modeling the Long-Term Evolution of Supraglacial Ice Cliffs on Himalayan Debris-Covered Glaciers

    Science.gov (United States)

    Buri, P.; Miles, E. S.; Steiner, J. F.; Ragettli, S.; Pellicciotti, F.

    2016-12-01

    Supraglacial ice cliffs are present on debris-covered glaciers worldwide and provide the only direct atmosphere-ice interface over the lower sections of these glaciers. Low albedo and high longwave emissions from surrounding debris cause very high melt rates, accounting for a significant portion of total glacier mass loss. As a result, ice cliffs affect glacier downwasting and mass balance. Additionally, and in contrast to the debris-covered ice, high melt at cliffs turns them into dynamic features, directly affecting glacier surface evolution. While conceptual ideas about the formation, evolution and collapse of ice cliffs exist, their life cycles have never been thoroughly documented. Based on observations obtained from high-resolution aerial and terrestrial images analyzed with Structure-from-Motion and with data from automatic weather stations on two glaciers in the Nepalese Himalaya, we simulate the evolution of selected ice cliffs over several seasons using a new physically-based model of cliff backwasting. The 3D model calculates the energy-balance at the cliff scale and includes the cliff interaction with supraglacial ponds and reburial by debris. We consider cliffs of different shape, orientation and slope, and we show that backwasting leads to a variety of evolution typologies, with cliffs that maintain a constant, self-similar geometry, cliffs that grow laterally and cliffs that disappear through slope shallowing and debris melt-out. Most cliffs persist over several seasons. The presence of a pond appears to be the key control for cliffs to survive, while east and west facing cliffs grow because of higher radiation receipts. We use the model to test the hypothesis that south-facing cliffs do not survive. We show that most south-facing cliffs demise after one melt season on both glaciers, because of high input of solar radiation exceeding the longwave radiation receipt. For north facing features, the longwave radiation receipts at lower cliff sections

  6. Environmental factors affecting long-term stabilization of radon suppression covers for uranium mill tailings

    International Nuclear Information System (INIS)

    Young, J.K.; Long, L.W.; Reis, J.W.

    1982-04-01

    Pacific Northwest Laboratory is investigating the use of a rock armoring blanket (riprap) to mitigate wind and water erosion of an earthen radon suppression cover applied to uranium mill tailings. To help determine design stresses for the tailings piles, environmental parameters are characterized for the five active uranium-producing regions on a site-specific basis. Only conventional uranium mills that are currently operating or that are scheduled to open in the mid 1980s are considered. Available data indicate that flooding has the most potential for disrupting a tailings pile. The arid regions of the Wyoming Basins and the Colorado Plateau are subject to brief storms of high intensity. The Texas Gulf Coast has the highest potential for extreme precipitation from hurricane-related storms. Wind data indicate average wind speeds from 3 to 6 m/sec for the sites, but extremes of 40 m/sec can be expected. Tornado risks range from low to moderate. The Colorado Plateau has the highest seismic potential, with maximum acceleration caused by earthquakes ranging from 0.2 to 0.4 g. Any direct effect from volcanic eruption is negligible, as all mills are located 90 km or more from an igneous or hydrothermal system

  7. Long-term variability in Northern Hemisphere snow cover and associations with warmer winters

    Science.gov (United States)

    McCabe, Gregory J.; Wolock, David M.

    2010-01-01

    A monthly snow accumulation and melt model is used with gridded monthly temperature and precipitation data for the Northern Hemisphere to generate time series of March snow-covered area (SCA) for the period 1905 through 2002. The time series of estimated SCA for March is verified by comparison with previously published time series of SCA for the Northern Hemisphere. The time series of estimated Northern Hemisphere March SCA shows a substantial decrease since about 1970, and this decrease corresponds to an increase in mean winter Northern Hemisphere temperature. The increase in winter temperature has caused a decrease in the fraction of precipitation that occurs as snow and an increase in snowmelt for some parts of the Northern Hemisphere, particularly the mid-latitudes, thus reducing snow packs and March SCA. In addition, the increase in winter temperature and the decreases in SCA appear to be associated with a contraction of the circumpolar vortex and a poleward movement of storm tracks, resulting in decreased precipitation (and snow) in the low- to mid-latitudes and an increase in precipitation (and snow) in high latitudes. If Northern Hemisphere winter temperatures continue to warm as they have since the 1970s, then March SCA will likely continue to decrease.

  8. Long-term evaluation for engineered capping (cover) of radioactive repository or landfill

    International Nuclear Information System (INIS)

    Mohd Jamil Hashim; Mohd Abdul Wahab Yusof

    2010-01-01

    This paper discussed the long-term evaluation of engineered capping for radioactive repository. It was done to gather knowledge and understand the suitability of granitic residual soil. Its resistance to hydrologic cycle and durability through a period of 100 to 300 years was checked. A hydrological program was used with forecast weather and manual checking all layers for hydraulic gradient to verify the results. Overall result shown that the grantic residual soil is able to last a few centuries before surcome to infiltration. (author)

  9. A comparison of evaluation metrics for biomedical journals, articles, and websites in terms of sensitivity to topic.

    Science.gov (United States)

    Fu, Lawrence D; Aphinyanaphongs, Yindalon; Wang, Lily; Aliferis, Constantin F

    2011-08-01

    Evaluating the biomedical literature and health-related websites for quality are challenging information retrieval tasks. Current commonly used methods include impact factor for journals, PubMed's clinical query filters and machine learning-based filter models for articles, and PageRank for websites. Previous work has focused on the average performance of these methods without considering the topic, and it is unknown how performance varies for specific topics or focused searches. Clinicians, researchers, and users should be aware when expected performance is not achieved for specific topics. The present work analyzes the behavior of these methods for a variety of topics. Impact factor, clinical query filters, and PageRank vary widely across different topics while a topic-specific impact factor and machine learning-based filter models are more stable. The results demonstrate that a method may perform excellently on average but struggle when used on a number of narrower topics. Topic-adjusted metrics and other topic robust methods have an advantage in such situations. Users of traditional topic-sensitive metrics should be aware of their limitations. Copyright © 2011 Elsevier Inc. All rights reserved.

  10. A Comparison of Evaluation Metrics for Biomedical Journals, Articles, and Websites in Terms of Sensitivity to Topic

    Science.gov (United States)

    Fu, Lawrence D.; Aphinyanaphongs, Yindalon; Wang, Lily; Aliferis, Constantin F.

    2011-01-01

    Evaluating the biomedical literature and health-related websites for quality are challenging information retrieval tasks. Current commonly used methods include impact factor for journals, PubMed’s clinical query filters and machine learning-based filter models for articles, and PageRank for websites. Previous work has focused on the average performance of these methods without considering the topic, and it is unknown how performance varies for specific topics or focused searches. Clinicians, researchers, and users should be aware when expected performance is not achieved for specific topics. The present work analyzes the behavior of these methods for a variety of topics. Impact factor, clinical query filters, and PageRank vary widely across different topics while a topic-specific impact factor and machine learning-based filter models are more stable. The results demonstrate that a method may perform excellently on average but struggle when used on a number of narrower topics. Topic adjusted metrics and other topic robust methods have an advantage in such situations. Users of traditional topic-sensitive metrics should be aware of their limitations. PMID:21419864

  11. [Short-term effect of black film covering on Oncomelania hupensis snail control in marshland and lake regions].

    Science.gov (United States)

    Zheng, Sheng-bang; Zhou, Yi-biao; Li, Lin-han; Wu, Jin-yi; Yao, Bao-dong; Zhu, Shao-ping; Wei, Cheng-jian; Li, Fu-ping; Hu, Ben-jiao; Ren, Guang-hui; Yi, Ping; Jiang, Qing-wu

    2013-08-01

    To evaluate the short-term effect of the black film covering combined with niclosamide on Oncomelania hupensis snail control in marshland and lake regions. A ditch with snails in Anxiang County was selected as the experimental sites. The ditch was divided into 3 groups: a film group, a niclosamide group, and a niclosamide and film group. The snails were surveyed before the test and 1, 3, 5, 7 days after the experiment. After the film covering, the highest temperature of the surface of soil was 63.7 degrees C on the first day, and the temperature higher than 40 degrees C lasted 4.34 hours. On the second day, the highest temperature was 52.3 degrees C, and the temperature higher than 40 degrees C lasted 4.96 hours. On the fourth day and fifth day, the temperature was lower than 30 degrees C, while the temperature was lower than 34 degrees C on the sixth day. On the seventh day of the experiment, the snail death rates of the film group, the niclosamide group, and the niclosamide and film group on the soil surface were 16.36%, 58.40% and 53.57%, respectively. On the seventh day, the snail death rates of the film group, and the niclosamide and film group under the soil were 20.00% and 40.00%, respectively, while no snails were found under the soil in the niclosamide group 3 days after the experiment. In mesh bags, the snail death rates of the film group, the niclosamide group, and the niclosamide and film group were 84.00%, 95.33% and 95.33%, respectively. The short-term effect of the black film covering on snail control is not obvious, and the black film covering does no promote the molluscicidal effect of niclosamide.

  12. JST Thesaurus Headwords and Synonyms: レビュー文献(as Topic) [MeCab user dictionary for science technology term[Archive

    Lifescience Database Archive (English)

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  16. Long-term effects of climate and land cover change on freshwater provision in the tropical Andes

    Science.gov (United States)

    Molina, A.; Vanacker, V.; Brisson, E.; Mora, D.; Balthazar, V.

    2015-06-01

    Andean headwater catchments play a pivotal role to supply fresh water for downstream water users. However, few long-term studies exist on the relative importance of climate change and direct anthropogenic perturbations on flow regimes. In this paper, we assess multi-decadal change in freshwater provision based on long time series (1974-2008) of hydrometeorological data and land cover reconstructions for a 282 km2 catchment located in the tropical Andes. Three main land cover change trajectories can be distinguished: (1) rapid decline of native vegetation in montane forest and páramo ecosystems in ~1/5 or 20% of the catchment area, (2) expansion of agricultural land by 14% of the catchment area, (3) afforestation of 12% of native páramo grasslands with exotic tree species in recent years. Given the strong temporal variability of precipitation and streamflow data related to El Niño-Southern Oscillation, we use empirical mode decomposition techniques to detrend the time series. The long-term increasing trend in rainfall is remarkably different from the observed changes in streamflow that exhibit a decreasing trend. Hence, observed changes in streamflow are not the result of long-term climate change but very likely result from direct anthropogenic disturbances after land cover change. Partial water budgets for montane cloud forest and páramo ecosystems suggest that the strongest changes in evaporative water losses are observed in páramo ecosystems, where progressive colonization and afforestation of high alpine grasslands leads to a strong increase in transpiration losses.

  17. Clinical Assessment of Immediate and Long-Term Effects of a Two-Step Topical Hyaluronic Acid Lip Treatment.

    Science.gov (United States)

    Makino, Elizabeth T; Tan, Priscilla; Qian, Kun; Babcock, Michael; Mehta, Rahul C

    2017-04-01

    Key features of lip aging include loss of volume, color, and definition as well as increases in lines/wrinkles and uneven skin texture. A single-center, open-label clinical study was conducted to assess the efficacy and tolerability of a novel, topical two-step lip treatment (HA5 LS) in female subjects presenting with mild to moderate lip dryness and mild to severe lip condition. Subjects were instructed to apply HA5 LS at least three times a day to ensure coverage 8 hours a day for four weeks. Clinical assessments for efficacy and tolerability were conducted at baseline, baseline post-application, week 2, and week 4. Standardized digital photography, subject self-assessment questionnaires, and instrumentation measurements for skin hydration (corneometer) and lip plumpness (digital caliper) were also conducted. Thirty-six female subjects aged 22-40 years enrolled in the study. HA5 LS provided instant and long term effects, achieving significant improvements in all clinical grading parameters including lip texture, color, definition/contour, scaling, cupping, lines/wrinkles, lip plumpness, and overall lip condition from baseline post-application to week 4 (all P less than equal to .001; Wilcoxon signed-rank test). Instrumentation measurements for hydration and digital caliper at weeks 2 and 4 were also significant (all P less than equal to .032; paired t-test). HA5 LS was also well-tolerated and highly-rated by subjects throughout the study duration. Results from this study suggest that HA5 LS addresses the key features of lip aging, providing both instant and long-term benefits. J Drugs Dermatol. 2017;16(4):366-371..

  18. Covered interest parity arbitrage and temporal long-term dependence between the US dollar and the Yen

    Science.gov (United States)

    Batten, Jonathan A.; Szilagyi, Peter G.

    2007-03-01

    Using a daily time series from 1983 to 2005 of currency prices in spot and forward USD/Yen markets and matching equivalent maturity short-term US and Japanese interest rates, we investigate the sensitivity of the difference between actual prices in forward markets to those calculated from differentials in short-term interest rates. According to a fundamental theorem in financial economics termed covered interest parity (CIP), the actual and estimated prices should be identical once transaction and other costs are accommodated. The paper presents three important findings: first, we find evidence of considerable variation in CIP deviations from equilibrium; second, these deviations have diminished significantly and by 2000 have been almost eliminated; third, an analysis of the CIP deviations using the local Hurst exponent finds episodes of time-varying dependence over the various sample periods, which appear to be linked to episodes of dollar decline/Yen appreciation, or vice versa. The finding of temporal long-term dependence in CIP deviations is consistent with recent evidence of temporal long-term dependence in the returns of currency, stock and commodity markets.

  19. Long-term use of cover crops and no-till shift soil microbial community life strategies in agricultural soil

    Science.gov (United States)

    Mitchell, Jeffrey; Scow, Kate

    2018-01-01

    Reducing tillage and growing cover crops, widely recommended practices for boosting soil health, have major impacts on soil communities. Surprisingly little is known about their impacts on soil microbial functional diversity, and especially so in irrigated Mediterranean ecosystems. In long-term experimental plots at the West Side Research and Extension Center in California’s Central Valley, we characterized soil microbial communities in the presence or absence of physical disturbance due to tillage, in the presence or absence of cover crops, and at three depths: 0–5, 5–15 and 15–30 cm. This characterization included qPCR for bacterial and archaeal abundances, DNA sequencing of the 16S rRNA gene, and phylogenetic estimation of two ecologically important microbial traits (rRNA gene copy number and genome size). Total (bacterial + archaeal) diversity was higher in no-till than standard till; diversity increased with depth in no-till but decreased with depth in standard till. Total bacterial numbers were higher in cover cropped plots at all depths, while no-till treatments showed higher numbers in 0–5 cm but lower numbers at lower depths compared to standard tillage. Trait estimates suggested that different farming practices and depths favored distinctly different microbial life strategies. Tillage in the absence of cover crops shifted microbial communities towards fast growing competitors, while no-till shifted them toward slow growing stress tolerators. Across all treatment combinations, increasing depth resulted in a shift towards stress tolerators. Cover crops shifted the communities towards ruderals–organisms with wider metabolic capacities and moderate rates of growth. Overall, our results are consistent with decreasing nutrient availability with soil depth and under no-till treatments, bursts of nutrient availability and niche homogenization under standard tillage, and increases in C supply and variety provided by cover crops. Understanding how

  20. Long Term Quantification of Climate and Land Cover Change Impacts on Streamflow in an Alpine River Catchment, Northwestern China

    Directory of Open Access Journals (Sweden)

    Zhenliang Yin

    2017-07-01

    Full Text Available Quantifying the long term impacts of climate and land cover change on streamflow is of great important for sustainable water resources management in inland river basins. The Soil and Water Assessment Tool (SWAT model was employed to simulate the streamflow in the upper reaches of Heihe River Basin, northwestern China, over the last half century. The Sequential Uncertainty Fitting algorithm (SUFI-2 was selected to calibrate and validate the SWAT model. The results showed that both Nash-Sutcliffe efficiency (NSE and determination coefficient (R2 were over 0.93 for calibration and validation periods, the percent bias (PBIAS of the two periods were—3.47% and 1.81%, respectively. The precipitation, average, maximum, and minimum air temperature were all showing increasing trends, with 14.87 mm/10 years, 0.30 °C/10 years, 0.27 °C/10 year, and 0.37 °C/10 years, respectively. Runoff coefficient has increased from 0.36 (averaged during 1964 to 1988 to 0.39 (averaged during 1989 to 2013. Based on the SWAT simulation, we quantified the contribution of climate and land cover change to streamflow change, indicated that the land cover change had a positive impact on river discharge by increasing 7.12% of the streamflow during 1964 to 1988, and climate change contributed 14.08% for the streamflow increasing over last 50 years. Meanwhile, the climate change impact was intensive after 2000s. The increasing of streamflow contributed to the increasing of total streamflow by 64.1% for cold season (November to following March and 35.9% for warm season (April to October. The results provide some references for dealing with climate and land cover change in an inland river basin for water resource management and planning.

  1. The effect of coverings, including plastic bags and wraps, on mortality and morbidity in preterm and full-term neonates.

    Science.gov (United States)

    Oatley, H K; Blencowe, H; Lawn, J E

    2016-05-01

    Neonatal hypothermia is an important risk factor for mortality and morbidity, and is common even in temperate climates. We conducted a systematic review to determine whether plastic coverings, used immediately following delivery, were effective in reducing the incidence of mortality, hypothermia and morbidity. A total of 26 studies (2271 preterm and 1003 term neonates) were included. Meta-analyses were conducted as appropriate. Plastic wraps were associated with a reduction in hypothermia in preterm (⩽29 weeks; risk ratio (RR)=0.57; 95% confidence interval (CI) 0.46 to 0.71) and term neonates (RR=0.76; 95% CI 0.60 to 0.96). No significant reduction in neonatal mortality or morbidity was found; however, the studies were underpowered for these outcomes. For neonates, especially preterm, plastic wraps combined with other environmental heat sources are effective in reducing hypothermia during stabilization and transfer within hospital. Further research is needed to quantify the effects on mortality or morbidity, and investigate the use of plastic coverings outside hospital settings or without additional heat sources.

  2. Long-term maintenance therapy for vulvar lichen sclerosus: the results of a randomized study comparing topical vitamin E with an emollient.

    Science.gov (United States)

    Virgili, Annarosa; Minghetti, Sara; Borghi, Alessandro; Corazza, Monica

    2013-04-01

    The chronic and relapsing nature of vulvar lichen sclerosus (VLS) represents a challenge for its long-term management after an effective treatment with topical corticosteroids. To compare the effect of topical vitamin E with that of an emollient in reducing the risk of VLS relapse over a 52-week maintenance treatment. 156 patients with VLS were enrolled in a 12-week active treatment phase on topical 0.1% mometasone furoate ointment once daily. Those who achieved disease remission entered a 52-week maintenance phase in which patients were randomized to apply either an emollient or topical vitamin E once daily. 80 patients entered the maintenance phase. At 52 weeks, for the vitamin E maintenance group, the cumulative crude relapse rate was 27.8% and the cumulative modified crude relapse rate was 55.6%. For the emollient maintenance group, the cumulative crude relapse rate was 22.7% and the cumulative modified crude relapse rate was 50.0%. The median time to relapse was 20 weeks for the vitamin E group and 18.7 weeks for the emollient group. Once VLS has been stabilized with topical corticosteroids, long-term treatment with both vitamin E and emollients may be considered in maintain LS remission.

  3. Nitrous Oxide Production at a Fully Covered Wastewater Treatment Plant: Results of a Long-Term Online Monitoring Campaign.

    Science.gov (United States)

    Kosonen, Heta; Heinonen, Mari; Mikola, Anna; Haimi, Henri; Mulas, Michela; Corona, Francesco; Vahala, Riku

    2016-06-07

    The nitrous oxide emissions of the Viikinmäki wastewater treatment plant were measured in a 12 month online monitoring campaign. The measurements, which were conducted with a continuous gas analyzer, covered all of the unit operations of the advanced wastewater-treatment process. The relation between the nitrous oxide emissions and certain process parameters, such as the wastewater temperature, influent biological oxygen demand, and ammonium nitrogen load, was investigated by applying online data obtained from the process-control system at 1 min intervals. Although seasonal variations in the measured nitrous oxide emissions were remarkable, the measurement data indicated no clear relationship between these emissions and seasonal changes in the wastewater temperature. The diurnal variations of the nitrous oxide emissions did, however, strongly correlate with the alternation of the influent biological oxygen demand and ammonium nitrogen load to the aerated zones of the activated sludge process. Overall, the annual nitrous oxide emissions of 168 g/PE/year and the emission factor of 1.9% of the influent nitrogen load are in the high range of values reported in the literature but in very good agreement with the results of other long-term online monitoring campaigns implemented at full-scale wastewater-treatment plants.

  4. Age, origin and evolution of Antarctic debris-covered glaciers: Implications for landscape evolution and long-term climate change

    Science.gov (United States)

    Mackay, Sean Leland

    Antarctic debris-covered glaciers are potential archives of long-term climate change. However, the geomorphic response of these systems to climate forcing is not well understood. To address this concern, I conducted a series of field-based and numerical modeling studies in the McMurdo Dry Valleys of Antarctica (MDV), with a focus on Mullins and Friedman glaciers. I used data and results from geophysical surveys, ice-core collection and analysis, geomorphic mapping, micro-meteorological stations, and numerical-process models to (1) determine the precise origin and distribution of englacial and supraglacial debris within these buried-ice systems, (2) quantify the fundamental processes and feedbacks that govern interactions among englacial and supraglacial debris, (3) establish a process-based model to quantify the inventory of cosmogenic nuclides within englacial and supraglacial debris, and (4) isolate the governing relationships between the evolution of englacial /supraglacial debris and regional climate forcing. Results from 93 field excavations, 21 ice cores, and 24 km of ground-penetrating radar data show that Mullins and Friedman glaciers contain vast areas of clean glacier ice interspersed with inclined layers of concentrated debris. The similarity in the pattern of englacial debris bands across both glaciers, along with model results that call for negligible basal entrainment, is best explained by episodic environmental change at valley headwalls. To constrain better the timing of debris-band formation, I developed a modeling framework that tracks the accumulation of cosmogenic 3He in englacial and supraglacial debris. Results imply that ice within Mullins Glacier increases in age non-linearly from 12 ka to ˜220 ka in areas of active flow (up to >> 1.6 Ma in areas of slow-moving-to-stagnant ice) and that englacial debris bands originate with a periodicity of ˜41 ka. Modeling studies suggest that debris bands originate in synchronicity with changes in

  5. Short-term winter wheat (Triticum aestivum L.) cover crop grazing influence on calf growth, grain yield, and soil properties

    Science.gov (United States)

    Winter cover cropping has many agronomic benefits and can provide forages base for spring livestock grazing. Winter cover crop grazing has shown immediate economic benefits through increased animal production. Winter wheat pasture grazing is common in beef cow-calf production and stocker operations....

  6. How are arbuscular mycorrhizal associations related to maize growth performance during short-term cover crop rotation?

    Science.gov (United States)

    Higo, Masao; Takahashi, Yuichi; Gunji, Kento; Isobe, Katsunori

    2018-03-01

    Better cover crop management options aiming to maximize the benefits of arbuscular mycorrhizal fungi (AMF) to subsequent crops are largely unknown. We investigated the impact of cover crop management methods on maize growth performance and assemblages of AMF colonizing maize roots in a field trial. The cover crop treatments comprised Italian ryegrass, wheat, brown mustard and fallow in rotation with maize. The diversity of AMF communities among cover crops used for maize management was significantly influenced by the cover crop and time course. Cover crops did not affect grain yield and aboveground biomass of subsequent maize but affected early growth. A structural equation model indicated that the root colonization, AMF diversity and maize phosphorus uptake had direct strong positive effects on yield performance. AMF variables and maize performance were related directly or indirectly to maize grain yield, whereas root colonization had a positive effect on maize performance. AMF may be an essential factor that determines the success of cover crop rotational systems. Encouraging AMF associations can potentially benefit cover cropping systems. Therefore, it is imperative to consider AMF associations and crop phenology when making management decisions. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  7. Evapotranspiration (ET) covers.

    Science.gov (United States)

    Rock, Steve; Myers, Bill; Fiedler, Linda

    2012-01-01

    Evapotranspiration (ET) cover systems are increasingly being used at municipal solid waste (MSW) landfills, hazardous waste landfills, at industrial monofills, and at mine sites. Conventional cover systems use materials with low hydraulic permeability (barrier layers) to minimize the downward migration of water from the surface to the waste (percolation), ET cover systems use water balance components to minimize percolation. These cover systems rely on soil to capture and store precipitation until it is either transpired through vegetation or evaporated from the soil surface. Compared to conventional membrane or compacted clay cover systems, ET cover systems are expected to cost less to construct. They are often aesthetic because they employ naturalized vegetation, require less maintenance once the vegetative system is established, including eliminating mowing, and may require fewer repairs than a barrier system. All cover systems should consider the goals of the cover in terms of protectiveness, including the pathways of risk from contained material, the lifecycle of the containment system. The containment system needs to be protective of direct contact of people and animals with the waste, prevent surface and groundwater water pollution, and minimize release of airborne contaminants. While most containment strategies have been based on the dry tomb strategy of keeping waste dry, there are some sites where adding or allowing moisture to help decompose organic waste is the current plan. ET covers may work well in places where complete exclusion of precipitation is not needed. The U.S. EPA Alternative Cover Assessment Program (ACAP), USDOE, the Nuclear Regulatory Commission, and others have researched ET cover design and efficacy, including the history of their use, general considerations in their design, performance, monitoring, cost, current status, limitations on their use, and project specific examples. An on-line database has been developed with information

  8. The long-term relationship between population growth and vegetation cover: an empirical analysis based on the panel data of 21 cities in Guangdong Province, China.

    Science.gov (United States)

    Li, Chao; Kuang, Yaoqiu; Huang, Ningsheng; Zhang, Chao

    2013-02-07

    It is generally believed that there is an inverse relationship between population growth and vegetation cover. However, reports about vegetation protection and reforestation around the World have been continuously increasing in recent decades, which seems to indicate that this relationship may not be true. In this paper, we have taken 21 cities in Guangdong Province, China as the study area to test the long-term relationship between population growth and vegetation cover, using an AVHRR NDVI data set and the panel cointegrated regression method. The results show that there is a long-term inverted N-shaped curve relationship between population growth and vegetation cover in the region where there are frequent human activities and the influence of climate change on vegetation cover changes is relatively small. The two turning points of the inverted N-shaped curve for the case of Guangdong Province correspond to 2,200 persons · km(-2) and 3,820 persons · km(-2), and they can provide a reference range for similar regions of the World. It also states that the population urbanization may have a negative impact on the vegetation cover at the early stage, but have a positive impact at the later stage. In addition, the Panel Error Correction Model (PECM) is used to investigate the causality direction between population growth and vegetation cover. The results show that not only will the consuming destruction effect and planting construction effect induced by the population growth have a great impact on vegetation cover changes, but vegetation cover changes in turn will also affect the population growth in the long term.

  9. The Long-Term Relationship between Population Growth and Vegetation Cover: An Empirical Analysis Based on the Panel Data of 21 Cities in Guangdong Province, China

    Directory of Open Access Journals (Sweden)

    Chao Li

    2013-02-01

    Full Text Available It is generally believed that there is an inverse relationship between population growth and vegetation cover. However, reports about vegetation protection and reforestation around the World have been continuously increasing in recent decades, which seems to indicate that this relationship may not be true. In this paper, we have taken 21 cities in Guangdong Province, China as the study area to test the long-term relationship between population growth and vegetation cover, using an AVHRR NDVI data set and the panel cointegrated regression method. The results show that there is a long-term inverted N-shaped curve relationship between population growth and vegetation cover in the region where there are frequent human activities and the influence of climate change on vegetation cover changes is relatively small. The two turning points of the inverted N-shaped curve for the case of Guangdong Province correspond to 2,200 persons·km−2 and 3,820 persons·km−2, and they can provide a reference range for similar regions of the World. It also states that the population urbanization may have a negative impact on the vegetation cover at the early stage, but have a positive impact at the later stage. In addition, the Panel Error Correction Model (PECM is used to investigate the causality direction between population growth and vegetation cover. The results show that not only will the consuming destruction effect and planting construction effect induced by the population growth have a great impact on vegetation cover changes, but vegetation cover changes in turn will also affect the population growth in the long term.

  10. Evaluation of risk of falls and orthostatic hypotension in older, long-term topical beta-blocker users

    NARCIS (Netherlands)

    Ramdas, Wishal D.; van der Velde, Nathalie; van der Cammen, Tischa J. M.; Wolfs, Roger C. W.

    2009-01-01

    Falls are a serious problem in the elderly, and have recently been described as cardiovascular-mediated side effects of beta-blocker eye drops. Therefore, we investigated the possible association between the long-term use of beta-blockers, prostaglandins and their combinations in eye drops, and

  11. Evaluation of risk of falls and orthostatic hypotension in older, long-term topical beta-blocker users

    NARCIS (Netherlands)

    W.D. Ramdas (Wishal); N. van der Velde (Nathalie); T.J.M. van der Cammen (Tischa); R.C.W. Wolfs (Roger)

    2009-01-01

    textabstractBackground: Falls are a serious problem in the elderly, and have recently been described as cardiovascular-mediated side effects of beta-blocker eye drops. Therefore, we investigated the possible association between the long-term use of beta-blockers, prostaglandins and their

  12. Evaluation of the influence of family and friends, and the Internet on patient perceptions of long-term topical corticosteroid use.

    Science.gov (United States)

    Smith, Saxon D; Farrugia, Lisa L; Harris, Victoria; Lee, Andrew; Carter, Stephen R; Blaszczynski, Alex; Fischer, Gayle

    2017-11-01

    Topical corticosteroids (TCS) are key to managing chronic inflammatory dermatoses (CID). Parents/patients cite TCS phobia as an impediment to treatment adherence. Family/friends and the Internet are a source of misinformation on TCS which can negatively impact perceptions of TCS safety. To assess information from family/friends and the Internet, as related to and reported by patients/parents using long-term TCS. A multicenter cross-sectional survey of patients (aged >18 years) and parents of patients (aged friends and the Internet. A total of 123 patients and 78 parents completed the survey (n = 201). Parents/patients were more likely to be informed by the Internet "[having] my [child's] skin condition means that [I/he/she] will need to use topical corticosteroids" (p friends were more likely to recommend parents/patients "try non-prescription creams/ointments before resorting to the use of prescription topical corticosteroids" (p = .014). High rates of messages about TCS "risk" from family/friends and the Internet may affect patient/parent understanding about TCS safety. This may contribute to treatment non-adherence.

  13. Short-term cover crop decomposition inorganic and conventional soils : Soil microbial and nutrient cycling indicator variables associated with different levels of soil suppressiveness to Pythium aphanidermatum

    NARCIS (Netherlands)

    Grünwald, N.J.; Hu, S.; Bruggen, van A.H.C.

    2000-01-01

    Stages of oat–vetch cover crop decomposition were characterized over time in terms of carbon and nitrogen cycling, microbial activity and community dynamics in organically and conventionally managed soils in a field experiment and a laboratory incubation experiment. We subsequently determined which

  14. Unravelling long-term vegetation change patterns in a binational watershed using multitemporal land cover data and historical photography

    Science.gov (United States)

    Villarreal, Miguel L.; Norman, Laura M.; Webb, Robert H.; Boyer, Diane E.; Turner, Raymond M.

    2011-01-01

    A significant amount of research conducted in the Sonoran Desert of North America has documented, both anecdotally and empirically, major vegetation changes over the past century due to human land use activities. However, many studies lack coincidental landscape-scale data characterizing the spatial and temporal manifestation of these changes. Vegetation changes in a binational (USA and Mexico) watershed were documented using a series of four land cover maps (1979-2009) derived from multispectral satellite imagery. Cover changes are compared to georeferenced, repeat oblique photographs dating from the late 19th century to present. Results indicate the expansion of grassland over the past 20 years following nearly a century of decline. Historical repeat photography documents early-mid 20th century mesquite invasions, but recent land cover data and rephotography demonstrate declines in xeroriparian/riparian mesquite communities in recent decades. These vegetation changes are variable over the landscape and influenced by topography and land management.

  15. Topics in industrial mathematics

    International Nuclear Information System (INIS)

    Vatsya, S.R.

    1992-01-01

    Mathematical methods are widely used to solve practical problems arising in modern industry. This article outlines some of the topics relevant to AECL programmes. This covers the applications of transmission and neutron transport tomography to determine density distributions in rocks and two phase flow situations. Another example covered is the use of variational methods to solve the problems of aerosol migration and control theory. (author). 7 refs

  16. A long-term assessment of the variability in winter use of dense conifer cover by female white-tailed deer.

    Directory of Open Access Journals (Sweden)

    Glenn D Delgiudice

    Full Text Available Long-term studies allow capture of a wide breadth of environmental variability and a broader context within which to maximize our understanding of relationships to specific aspects of wildlife behavior. The goal of our study was to improve our understanding of the biological value of dense conifer cover to deer on winter range relative to snow depth and ambient temperature.We examined variation among deer in their use of dense conifer cover during a 12-year study period as potentially influenced by winter severity and cover availability. Female deer were fitted with a mixture of very high frequency (VHF, n = 267 and Global Positioning System (GPS, n = 24 collars for monitoring use of specific cover types at the population and individual levels, respectively. We developed habitat composites for four study sites. We fit multinomial response models to VHF (daytime data to describe population-level use patterns as a function of snow depth, ambient temperature, and cover availability. To develop alternative hypotheses regarding expected spatio-temporal patterns in the use of dense conifer cover, we considered two sets of competing sub-hypotheses. The first set addressed whether or not dense conifer cover was limiting on the four study sites. The second set considered four alternative sub-hypotheses regarding the potential influence of snow depth and ambient temperature on space use patterns. Deer use of dense conifer cover increased the most with increasing snow depth and most abruptly on the two sites where it was most available, suggestive of an energy conservation strategy. Deer use of dense cover decreased the most with decreasing temperatures on the sites where it was most available. At all four sites deer made greater daytime use (55 to >80% probability of use of open vegetation types at the lowest daily minimum temperatures indicating the importance of thermal benefits afforded from increased exposure to solar radiation. Date

  17. The Future Through the Past: The Use of Analog Sites for Design Criteria and Long Term Performance Assessment of Evapotranspiration Landfill Covers

    Energy Technology Data Exchange (ETDEWEB)

    Shafer, D. S.; Miller, J. J.; Young, M. H.; Edwards, S. C.; Rawlinson, S. E.

    2002-02-26

    There is growing support for using evapotranspiration (ET) covers for closure of low-level waste (LLW) and other types of waste disposal sites, particularly in the lower latitude arid regions of the western United States. At the Nevada Test Site (NTS), monolayer ET covers are the baseline technology for closure of LLW and mixed LLW cells. To better predict the long-term performance of monolayer ET covers, as well as to identify design criteria that will potentially improve their performance, the properties of, and processes occurring on, analog sites for ET covers on the NTS are being studied. The project is funded through the Subsurface Contaminants Focus Area of the U.S. Department of Energy. Four analog sites on the NTS have been selected to predict performance of ET covers over a 1,000-year compliance period. Two sites are relatively recently disturbed (within the last 50 years) and have been selected to evaluate processes and changes on ET covers for the early period after active cover maintenance is discontinued. Two other sites, late to mid-Holocene in age, are intended as analogs for the end of the compliance period (1,000 years or more); both surfaces are abandoned alluvial/colluvial deposits. The history of the early post-institutional control analog sites are being evaluated by an archaeologist to help determine when the sites were last disturbed or modified, and the mode of disturbance to help set baseline conditions. Similar to other ''landforms,'' ET covers will evolve over time because of pedogenic, biotic, and climatic processes. Properties of analog sites that could affect ET water balance performance will be evaluated to help understand ET cover performance over time.

  18. Development of a long-term post-closure radiation monitor: Phase 2, Topical report, March 1994--July 1995

    International Nuclear Information System (INIS)

    Reed, S.E.

    1995-07-01

    The long-term monitoring of a hazardous waste site for migration of radionuclides requires installation of radiation sensors at a large number of subsurface locations. The concept under development employs a passive in-ground measurement probe which contains a scintillator coupled to an optical lightguide. The overall goal of the Long-Term Post-Closure Radiation Monitor System (LPRMS) development program is to configure a long-term radiation monitor using commercially available, demonstrated components to the largest extent possible. The development program is planned as a three phase program spanning a total time of 53 months. The problems to be solved during Phase 1 were primarily those associated with selection of the most appropriate components (scintillator, coupling optics, optical fiber, and opto-electronics) to maximize the signal reaching the detectors and thereby minimizing the integration time required to obtain a reliable measure of radiation. Phase 2 (the current Phase) encompassed the fabrication and testing of the prototype LPRMS probe at a contaminated DOE site, the Fernald Environmental Management Project, in southwestern Ohio. Uranium isotopes are the primary contaminants of concern at this site. The single probe and opto-electronic device were used to made measurements in-situ at relatively shallow subsurface depths. The end objective of Phase 2 was the design of a full-scale prototype system which incorporates all the features expected to be necessary on a commercial system, including 50 meter depth of measurement, multiplexing of multiple probes, and remote transmission of data. This full-scale prototype will be fabricated and field tested for 12 months during Phase 3, and a commercial design will be developed based upon the data gathered and experience gained during the entire program

  19. The Long-Term Impact of Foreign Multinational Enterprises in Spain: New Insights into an Old Topic

    Directory of Open Access Journals (Sweden)

    Núria Puig

    2016-07-01

    Full Text Available The role of foreign capital and technology in the economic and social progress of late-developing countries remains a controversial issue in both academic and policy circles. In this essay, we examine the case of Spain in the light of the academic literature from the 1960s to the present. First, we identify and contextualize the intellectual concerns and controversies of two important generations of economists and historians and their approaches to the specific issue of multinational enterprises (MNEs. We then discuss what we consider to be the seven major contributions of recent Spanish scholarship in terms of: 1/ new quantitative evidence on FDI inward flows and firm demography analyses of foreign MNEs; 2/ new approaches to the transfer of technology by MNEs; 3/ collective and individual case studies of foreign MNEs, with a focus on their impact on local capabilities; 4/ identification of patterns of investment by MNE home countries; 5/ identification and study of the local actors of inward FDI; 6/ new perspectives gained from the history of international relations; and 7 new evidence on processes leading from inward FDI to outward FDI. We argue that the time is ripe for comprehensive re-assessments of the long-term impact of foreign MNEs and the role of Spain in the global economy.

  20. Earthworm populations are affected from Long-Term Crop Sequences and Bio-Covers under No-Tillage

    Science.gov (United States)

    Earthworms are crucial for improving soil biophysical properties in cropping systems. Consequently, effects of cropping rotation and bio-covers were assessed on earthworm populations under no-tillage sites. Main effects of 6 different cropping sequences [corn (Zea mays), cotton (Gossypium hirsutum),...

  1. Efficacy and short-term safety of topical Dwarf Elder (Sambucus ebulus L.) versus diclofenac for knee osteoarthritis: A randomized, double-blind, active-controlled trial.

    Science.gov (United States)

    Jabbari, Marzie; Hashempur, Mohammad Hashem; Razavi, Seyede Zahra Emami; Shahraki, Hadi Raeisi; Kamalinejad, Mohammad; Emtiazy, Majid

    2016-07-21

    Sambucus ebulus L. (S. ebulus) has had long-standing application in Traditional Persian Medicine for joint pain and for a variety of bone and joint disorders. According to traditional use of S. ebulus and its relevant pharmacologic properties, this study was designed to evaluate the efficacy and short-term safety of topical use of S. ebulus in patients with knee osteoarthritis (OA). Seventy nine patients with knee OA were randomly enrolled in 2 parallel arms of a pilot randomized, double-blind, active-controlled clinical trial. The patients were treated by topical S. ebulus gel or 1% diclofenac gel, three times a day, as much as a fingertip unit for 4 weeks. Patients were assessed prior to enrollment and, then, 2 and 4 weeks subsequent to the intervention, in terms of scores of visual analogue scale (VAS) for self-grading of their knee joint pain, and according to 3 different domains of Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire. Any observed adverse effects were also scrutinized. The mean values of WOMAC pain score, total WOMAC score and VAS score for pain of the S. ebulus group were significantly lower compared with the diclofenac group (P=0.004, P=0.04, and P<0.001, respectively). In addition, no serious adverse effect was reported. This pilot study showed that topical treatment with S. ebulus gel can be recommended for alleviating symptoms of patients with knee OA. However, longer trials involving larger samples size, are needed for achieving a comprehensive understanding about the efficacy and safety of S. ebulus in knee OA. Copyright © 2016. Published by Elsevier Ireland Ltd.

  2. Development of a Risk-Based Performance Assessment Method for Long-Term Cover Systems--Application to the Monticello Mill Tailings Repository

    International Nuclear Information System (INIS)

    HO, CLIFFORD K.; ARNOLD, BILL W.; COCHRAN, JOHN R.; WEBB, STEPHEN W.; TAIRA, RANDAL Y.

    2001-01-01

    A probabilistic, risk-based performance-assessment methodology is being developed to assist designers, regulators, and involved stakeholders in the selection, design, and monitoring of long-term covers for contaminated subsurface sites. This report presents an example of the risk-based performance-assessment method using a repository site in Monticello, Utah. At the Monticello site, a long-term cover system is being used to isolate long-lived uranium mill tailings from the biosphere. Computer models were developed to simulate relevant features, events, and processes that include water flux through the cover, source-term release, vadose-zone transport, saturated-zone transport, gas transport, and exposure pathways. The component models were then integrated into a total-system performance-assessment model, and uncertainty distributions of important input parameters were constructed and sampled in a stochastic Monte Carlo analysis. Multiple realizations were simulated using the integrated model to produce cumulative distribution functions of the performance metrics, which were used to assess cover performance for both present- and long-term future conditions. Performance metrics for this study included the water percolation reaching the uranium mill tailings, radon flux at the surface, groundwater concentrations, and dose. Results of this study can be used to identify engineering and environmental parameters (e.g., liner properties, long-term precipitation, distribution coefficients) that require additional data to reduce uncertainty in the calculations and improve confidence in the model predictions. These results can also be used to evaluate alternative engineering designs and to identify parameters most important to long-term performance

  3. Testosterone Topical

    Science.gov (United States)

    ... not apply any testosterone topical products to your penis or scrotum or to skin that has sores, ... are severe or do not go away: breast enlargement and/or pain decreased sexual desire acne depression ...

  4. Effects of land cover and regional climate variations on long-term spatiotemporal changes in sagebrush ecosystems

    Science.gov (United States)

    Xian, George Z.; Homer, Collin G.; Aldridge, Cameron L.

    2012-01-01

    This research investigated the effects of climate and land cover change on variation in sagebrush ecosystems. We combined information of multi-year sagebrush distribution derived from multitemporal remote sensing imagery and climate data to study the variation patterns of sagebrush ecosystems under different potential disturbances. We found that less than 40% of sagebrush ecosystem changes involved abrupt changes directly caused by landscape transformations and over 60% of the variations involved gradual changes directly related to climatic perturbations. The primary increases in bare ground and declines in sagebrush vegetation abundance were significantly correlated with the 1996-2006 decreasing trend in annual precipitation.

  5. Guam Long-term Coral Reef Monitoring Program Benthic Percent Cover Derived from Image Analysis since 2010

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Government of Guam's Long-term Coral Reef Monitoring Program, coordinated through the Guam Coastal Management Program until October 2013 and now coordinated...

  6. Long-term survivability of riprap for armoring uranium-mill tailings and covers: a literature review. [203 references

    Energy Technology Data Exchange (ETDEWEB)

    Lindsey, C.G.; Long, L.W.; Begej, C.W.

    1982-06-01

    Pacific Northwest Laboratory (PNL) is investigating the use of a rock armoring blanket (riprap) to mitigate wind and water erosion of an earthen radon suppression cover applied to uranium mill tailings. Because the radon suppression cover and the tailings must remain intact for up to 1000 years or longer, the riprap must withstand natural weathering forces. This report is a review of information on rock weathering and riprap durability. Chemical and physical weathering processes, rock characteristics related to durability, climatic conditions affecting the degree and rate of weathering, and testing procedures used to measure weathering susceptibilities have been reviewed. Sampling and testing techniques, as well as analyses of physical and chemical weathering susceptibilities, are necessary to evaluate rock durability. Many potential riprap materials may not be able to survive 1000 years of weathering. Available techniques for durability testing cannot adequately predict rock durability for the 1000-year period because they do not consider the issue of time (i.e., how long must riprap remain stable). This report includes an Appendix, which discusses rock weathering, written by Dr. Richard Jahns of Stanford University.

  7. Long-term survivability of riprap for armoring uranium-mill tailings and covers: a literature review

    International Nuclear Information System (INIS)

    Lindsey, C.G.; Long, L.W.; Begej, C.W.

    1982-06-01

    Pacific Northwest Laboratory (PNL) is investigating the use of a rock armoring blanket (riprap) to mitigate wind and water erosion of an earthen radon suppression cover applied to uranium mill tailings. Because the radon suppression cover and the tailings must remain intact for up to 1000 years or longer, the riprap must withstand natural weathering forces. This report is a review of information on rock weathering and riprap durability. Chemical and physical weathering processes, rock characteristics related to durability, climatic conditions affecting the degree and rate of weathering, and testing procedures used to measure weathering susceptibilities have been reviewed. Sampling and testing techniques, as well as analyses of physical and chemical weathering susceptibilities, are necessary to evaluate rock durability. Many potential riprap materials may not be able to survive 1000 years of weathering. Available techniques for durability testing cannot adequately predict rock durability for the 1000-year period because they do not consider the issue of time (i.e., how long must riprap remain stable). This report includes an Appendix, which discusses rock weathering, written by Dr. Richard Jahns of Stanford University

  8. Main alloy elements in covered electrodes in terms of the amount of oxygen in weld metal deposits (WMD

    Directory of Open Access Journals (Sweden)

    T. Węgrzyn

    2012-04-01

    Full Text Available There were investigated properties of WMD, especially metallographic structure, toughness and fatigue strength of welds with various oxygen amount. The connection between the properties of welds with the content of oxygen in WMD were carried out. The research results indicate that it should be limited oxygen content in steel welds. Subsequent researchers could find more precisely the most beneficial oxygen amount in the welds in terms of the amount of acicular ferrite in welds.

  9. Vegetation cover and long-term conservation of radioactive waste packages: the case study of the CSM waste disposal facility (Manche District, France).

    Science.gov (United States)

    Petit-Berghem, Yves; Lemperiere, Guy

    2012-03-01

    The CSM is the first French waste disposal facility for radioactive waste. Waste material is buried several meters deep and protected by a multi-layer cover, and equipped with a drainage system. On the surface, the plant cover is a grassland vegetation type. A scientific assessment has been carried out by the Géophen laboratory, University of Caen, in order to better characterize the plant cover (ecological groups and associated soils) and to observe its medium and long term evolution. Field assessments made on 10 plots were complemented by laboratory analyses carried out over a period of 1 year. The results indicate scenarios and alternative solutions which could arise, in order to passively ensure the long-term safety of the waste disposal system. Several proposals for a blanket solution are currently being studied and discussed, under the auspices of international research institutions in order to determine the most appropriate materials for the storage conditions. One proposal is an increased thickness of these materials associated with a geotechnical barrier since it is well adapted to the forest plants which are likely to colonize the site. The current experiments that are carried out will allow to select the best option and could provide feedback for other waste disposal facility sites already being operated in France (CSFMA waste disposal facility, Aube district) or in other countries.

  10. Bimatoprost Topical

    Science.gov (United States)

    ... not use a cotton swab or any other brush or applicator to apply topical bimatoprost.To use the solution, follow these steps: Wash your hands and face thoroughly with soap and water. Be sure that all makeup is removed. Do not let the tip of ...

  11. COMET strongly supported the development and implementation of medium-term topical research roadmaps consistent with the ALLIANCE Strategic Research Agenda.

    Science.gov (United States)

    Garnier-Laplace, J; Vandenhove, H; Beresford, N; Muikku, M; Real, A

    2018-03-01

    The ALLIANCE 6 Strategic Research Agenda (SRA) initiated by the STAR 7 Network of Excellence and integrated in the research strategy implemented by the COMET consortium, defines a long-term vision of the needs for, and implementation of, research in radioecology. This reference document, reflecting views from many stakeholders groups and researchers, serves as an input to those responsible for defining EU research call topics through the ALLIANCE SRA statement delivered each year to the EJP-CONCERT 8 (2015-2020). This statement highlights a focused number of priorities for funding. Research in radioecology and related sciences is justified by various drivers, such as policy changes, scientific advances and knowledge gaps, radiological risk perception by the public, and a growing awareness of interconnections between human and ecosystem health. The SRA is being complemented by topical roadmaps that have been initiated by the COMET 9 EC-funded project, with the help and endorsement of the ALLIANCE. The strategy underlying roadmap development is driven by the need for improved mechanistic understanding across radioecology. By meeting this need, we can provide fit-for-purpose human and environmental impact/risk assessments in support of the protection of man and the environment in interaction with society and for the three exposure situations defined by the ICRP (i.e., planned, existing and emergency). Within the framework of the EJP-CONCERT the development of a joint roadmap is under discussion among all the European research platforms and will highlight the major research needs for the whole radiation protection field and how these are likely to be addressed by 2030.

  12. Short-term effect of topical antiglaucoma medication on tear-film stability, tear secretion, and corneal sensitivity in healthy subjects.

    Science.gov (United States)

    Terai, Naim; Müller-Holz, Matthias; Spoerl, Eberhard; Pillunat, Lutz E

    2011-01-01

    The purpose of this study was to investigate the short-term effect of topical antiglaucoma medication on tear-film stability, tear secretion, and corneal sensitivity in healthy subjects. In this prospective, double-blind crossover trial, break-up time and basal secretion (Jones test) were measured 60 minutes before, and 30, 60, and 90 minutes after topical antiglaucoma drop application in 30 healthy subjects. Corneal sensitivity was measured 60 minutes before, and five, 10, and 15 minutes after drop application using a Cochet-Bonnet esthesiometer. Reduction of break-up time in the latanoprost group was -23.8% after 30 minutes (P = 0.21), -26.7% after 60 minutes (P = 0.03) and -51.4% after 90 minutes (P ≤ 0.003), which was statistically significant. Reduction of break-up time in all other treatment groups was not statistically significant. The Jones test revealed a significant reduction of basal secretion after application of brimonidine (-17.8%, P = 0.002; -22.5%, P < 0.001; -30.5%, P < 0.001), followed by apraclonidine (-10%, P = 0.06; -20.1%, P = 0.02; -22.1%, P = 0.002), latanoprost (-2.4%, P = 0.64; -18.6%, P = 0.001; -20.1%, P = 0.001) and dorzolamide (-0.5%, P = 0.9; 14.3%, P = 0.018; -17.3%, P = 0.004) at 30, 60, and 90 minutes after drop application. Reduction of basal secretion in all other treatment groups was not statistically significant. Latanoprost showed the most statistically significant reduction in break-up time, and brimonidine showed the most significant reduction in basal secretion of all the glaucoma medications used in this study. In conclusion, our data may be helpful for treatment decisions in glaucoma patients who also suffer from ocular surface problems.

  13. Long term testing and evaluation of PV modules with and without Sunarc antireflective coating of the cover glass

    DEFF Research Database (Denmark)

    Perers, Bengt; Furbo, Simon; Han, Jiangong

    2015-01-01

    Two Photovoltaic (PV) modules have been manufactured by Swemodule. One with Sunarc antireflective coated glass and one without glass surface treatment. The modules have been tested at DTU during 16 months under realistic outdoor conditions. Exactly the same polycrystalline cells were used...... in the modules. No cleaning of the glass has been made except for removal of bird droppings and leaves on single cells that could give a very wrong comparison. The PV modules were mounted due south at 45 degree tilt angle. They were connected to the electric grid with small 250W module inverters from Involar...... that also realized the MPP tracking to give the maximum output of each module. The electric power output was measured both on the AC and DC side and with different measurement equipment to be sure about the accuracy in improvement. The results indicate a potential long term improvement in a system from 3...

  14. Influence of covered stent versus bare stent on long-term efficacy of transjugular intrahepatic portosystemic shunt: a meta-analysis

    Directory of Open Access Journals (Sweden)

    XU Lu

    2016-10-01

    Full Text Available Objective To investigate the long-term postoperative efficacy of transjugular intrahepatic portosystemic shunt (TIPS using polytetrafluoroethylene (PTFE-covered stent or bare stent, and to provide a basis of evidence-based medicine for the selection of stent in TIPS. Methods CBM, Wanfang Data, CNKI, VIP, MEDLINE, and PubMed were searched for controlled trials on TIPS in the treatment of cirrhotic portal hypertension published form 1989 to 2015; the studies which met the inclusion criteria were selected, and quality assessment was performed for these articles. RevMan 5.3 software was used to analyze the incidence rates of stent dysfunction and hepatic encephalopathy and 1-year survival rate after TIPS, and funnel plots were used to analyze publication bias. Results A total of 11 studies were included, consisting of 698 patients in PTFE-covered stent group and 1283 patients in bare stent group. The results of the meta-analysis showed that the PTFE-covered stent group showed a significantly lower incidence rate of stent dysfunction than the bare stent group (14.8% vs 47.0%, OR=0.18, 95% CI: 0.13-0.24, P<0.001. There was no significant difference in the incidence rate of hepatic encephalopathy between the two groups (23.5% vs 25.7%, OR=0.88, 95% CI: 0.66-1.17, P=0.37. The PTFE-covered stent group had a significantly higher 1-year survival rate than the bare stent group (76.9% vs 62.7%, OR=2.10, 95% CI: 1.54-2.85, P<0.001. The funnel plots which were plotted based on the incidence rates of stent dysfunction and hepatic encephalopathy and 1-year survival rate lacked symmetry, which suggested that a certain degree of publication bias might exist. Conclusion Compared with the bare stent, the PTFE-covered stent can improve stent dysfunction and 1-year survival rate after TIPS, while there is no significant change in the incidence rate of hepatic encephalopathy. Therefore, the PTFE-covered stent has certain advantages over the bare stent in TIPS. In

  15. Topical anesthesia

    Directory of Open Access Journals (Sweden)

    Mritunjay Kumar

    2015-01-01

    Full Text Available Topical anesthetics are being widely used in numerous medical and surgical sub-specialties such as anesthesia, ophthalmology, otorhinolaryngology, dentistry, urology, and aesthetic surgery. They cause superficial loss of pain sensation after direct application. Their delivery and effectiveness can be enhanced by using free bases; by increasing the drug concentration, lowering the melting point; by using physical and chemical permeation enhancers and lipid delivery vesicles. Various topical anesthetic agents available for use are eutectic mixture of local anesthetics, ELA-max, lidocaine, epinephrine, tetracaine, bupivanor, 4% tetracaine, benzocaine, proparacaine, Betacaine-LA, topicaine, lidoderm, S-caine patch™ and local anesthetic peel. While using them, careful attention must be paid to their pharmacology, area and duration of application, age and weight of the patients and possible side-effects.

  16. Uptake of silica covered Quantum Dots into living cells: Long term vitality and morphology study on hyaluronic acid biomaterials

    International Nuclear Information System (INIS)

    D'Amico, Michele; Fiorica, Calogero; Palumbo, Fabio Salvatore; Militello, Valeria; Leone, Maurizio; Dubertret, Benoit; Pitarresi, Giovanna; Giammona, Gaetano

    2016-01-01

    Quantum Dots (QDs) are promising very bright and stable fluorescent probes for optical studies in the biological field but water solubility and possible metal bio-contamination need to be addressed. In this work, a simple silica-QD hybrid system is prepared and the uptake in bovine chondrocytes living cells without any functionalization of the external protective silica shield is demonstrated. Moreover, long term treated cells vitality (up to 14 days) and the transfer of silica-QDs to the next cell generations are here reported. Confocal fluorescence microscopy was also used to determine the morphology of the so labelled cells and the relative silica-QDs distribution. Finally, we employ silica-QD stained chondrocytes to characterize, as proof of concept, hydrogels obtained from an amphiphilic derivative of hyaluronic acid (HA-EDA-C _1_8) functionalized with different amounts of the RGD peptide. - Highlights: • Non functionalized silica-quantum dots fluorescent nanoparticles uptake is observed. • Morphology studies of such cells could be done by confocal fluorescence microscopy. • Labelled chondrocytes are viable until at least 14 days. • RGD functionalized Hyaluronic Acid hydrogels are studied as cell scaffolds. • Chondrocyte are promptly attached on RGD-functionalized hydrogels.

  17. Uptake of silica covered Quantum Dots into living cells: Long term vitality and morphology study on hyaluronic acid biomaterials

    Energy Technology Data Exchange (ETDEWEB)

    D' Amico, Michele [Dip. Biomedico di Medicina Interna e Specialistica, Universitá degli Studi di Palermo, Piazza delle Cliniche, 2, 90127 Palermo (Italy); Dip. di Fisica e Chimica, Universitá degli Studi di Palermo, Viale delle Scienze, Ed. 18, 90128 Palermo (Italy); Fiorica, Calogero, E-mail: calogero.fiorica@unipa.it [Dip. di Scienze e Tecnologie Molecolari e Biomolecolari, Sezione di Chimica e Tecnologie Farmaceutiche, Universitá degli Studi di Palermo, Via Archirafi, 28, 90136 Palermo (Italy); Palumbo, Fabio Salvatore [Dip. di Scienze e Tecnologie Molecolari e Biomolecolari, Sezione di Chimica e Tecnologie Farmaceutiche, Universitá degli Studi di Palermo, Via Archirafi, 28, 90136 Palermo (Italy); Militello, Valeria; Leone, Maurizio [Dip. di Fisica e Chimica, Universitá degli Studi di Palermo, Viale delle Scienze, Ed. 18, 90128 Palermo (Italy); Dubertret, Benoit [Laboratoire de Physique et d’Etude des Matèriaux, ESPCI-ParisTech, PSL Research University, Sorbonne Universitè UPMC Univ. Paris 06, CNRS, 10 rue Vauquelin, 75005 Paris (France); Pitarresi, Giovanna; Giammona, Gaetano [Dip. di Scienze e Tecnologie Molecolari e Biomolecolari, Sezione di Chimica e Tecnologie Farmaceutiche, Universitá degli Studi di Palermo, Via Archirafi, 28, 90136 Palermo (Italy)

    2016-10-01

    Quantum Dots (QDs) are promising very bright and stable fluorescent probes for optical studies in the biological field but water solubility and possible metal bio-contamination need to be addressed. In this work, a simple silica-QD hybrid system is prepared and the uptake in bovine chondrocytes living cells without any functionalization of the external protective silica shield is demonstrated. Moreover, long term treated cells vitality (up to 14 days) and the transfer of silica-QDs to the next cell generations are here reported. Confocal fluorescence microscopy was also used to determine the morphology of the so labelled cells and the relative silica-QDs distribution. Finally, we employ silica-QD stained chondrocytes to characterize, as proof of concept, hydrogels obtained from an amphiphilic derivative of hyaluronic acid (HA-EDA-C {sub 18}) functionalized with different amounts of the RGD peptide. - Highlights: • Non functionalized silica-quantum dots fluorescent nanoparticles uptake is observed. • Morphology studies of such cells could be done by confocal fluorescence microscopy. • Labelled chondrocytes are viable until at least 14 days. • RGD functionalized Hyaluronic Acid hydrogels are studied as cell scaffolds. • Chondrocyte are promptly attached on RGD-functionalized hydrogels.

  18. Cover crop rotations in no-till system: short-term CO2 emissions and soybean yield

    Directory of Open Access Journals (Sweden)

    João Paulo Gonsiorkiewicz Rigon

    Full Text Available ABSTRACT: In addition to improving sustainability in cropping systems, the use of a spring and winter crop rotation system may be a viable option for mitigating soil CO2 emissions (ECO2. This study aimed to determine short-term ECO2 as affected by crop rotations and soil management over one soybean cycle in two no-till experiments, and to assess the soybean yields with the lowest ECO2. Two experiments were carried out in fall-winter as follows: i triticale and sunflower were grown in Typic Rhodudalf (TR, and ii ruzigrass, grain sorghum, and ruzigrass + grain sorghum were grown in Rhodic Hapludox (RH. In the spring, pearl millet, sunn hemp, and forage sorghum were grown in both experiments. In addition, in TR a fallow treatment was also applied in the spring. Soybean was grown every year in the summer, and ECO2 were recorded during the growing period. The average ECO2 was 0.58 and 0.84 g m2 h–1 with accumulated ECO2 of 5,268 and 7,813 kg ha–1 C-CO2 in TR and RH, respectively. Sunn hemp, when compared to pearl millet, resulted in lower ECO2 by up to 12 % and an increase in soybean yield of 9% in TR. In RH, under the winter crop Ruzigrazz+Sorghum, ECO2 were lower by 17%, although with the same soybean yield. Soil moisture and N content of crop residues are the main drivers of ECO2 and soil clay content seems to play an important role in ECO2 that is worthy of further studies. In conclusion, sunn hemp in crop rotation may be utilized to mitigate ECO2 and improve soybean yield.

  19. Land Cover

    Data.gov (United States)

    Kansas Data Access and Support Center — The Land Cover database depicts 10 general land cover classes for the State of Kansas. The database was compiled from a digital classification of Landsat Thematic...

  20. Antimicrobial topical agents used in the vagina.

    Science.gov (United States)

    Frey Tirri, Brigitte

    2011-01-01

    Vaginally applied antimicrobial agents are widely used in the vagina in women with lower genital tract infections. An 'antimicrobial' is a general term that refers to a group of drugs that are effective against bacteria, fungi, viruses and protozoa. Topical treatments can be prescribed for a wide variety of vaginal infections. Many bacterial infections, such as bacterial vaginosis, desquamative inflammatory vaginitis or, as some European authors call it, aerobic vaginitis as well as infection with Staphylococcus aureus or group A streptococci, may be treated in this way. Candida vulvovaginitis is a fungal infection that is very amenable to topical treatment. The most common viral infections which can be treated with topical medications are condylomata acuminata and herpes simplex. The most often encountered protozoal vaginitis, which is caused by Trichomonas vaginalis, may be susceptible to topical medications, although this infection is treated systemically. This chapter covers the wide variety of commonly used topical antimicrobial agents for these diseases and focuses on the individual therapeutic agents and their clinical efficacy. In addition, potential difficulties that can occur in practice, as well as the usage of these medications in the special setting of pregnancy, are described in this chapter. Copyright © 2011 S. Karger AG, Basel.

  1. Car Covers | Outdoor Covers Canada

    OpenAIRE

    Covers, Outdoor

    2018-01-01

    Protect your car from the elements with Ultimate Touch Car Cover. The multi-layer non-woven fabric is soft on the finish and offers 4 seasons all weather protection.https://outdoorcovers.ca/car-covers/

  2. Could the long term cover change of three Mediterranean shrubs be explained by their photosynthetic responses to drought in a rainfall exclusion experiment ?

    Science.gov (United States)

    Liberati, Dario; De Dato, Giovanbattista; Guidolotti, Gabriele; De Angelis, Paolo

    2013-04-01

    In the Mediterranean climates water stress is considered to be the main environmental factor limiting plant growth. In front of water limitations plants have developed a wide diversity of adaptation mechanism, and co-occurring species often display different physiological, functional, and life history strategies. In the contest of a rainfall exclusion experiment (project INCREASE), the present work is aimed to assess if the seasonal response of photosynthesis to the water stress (based on gas exchange data collected during 2010) can explain the long term change in the cover degree (assessed by seven pin point survey carried out from 2001 to 2012) of the three main species present in the Italian experimental site, Cistus monspeliensis L. (Cistaceae), Dorycnium pentaphyllum Scop. (Fabaceae) and Helichrysum italicum subsp. microphyllum (Willd.) Nyman (Asteraceae) From 2001 to 2012, in the untreated plots, the cover degree increased in C. monspeliensis (+ 0.34% per year), did not show any significant trend in D. pentaphyllum and decreased in H. italicum (- 1.54% per year). In the same period the rainfall exclusion system has worked during Spring and Autumn, mainly reducing the soil water content of the drought plots in Autumn: this treatment did not affect the cover trend of D. pentaphyllum and H. italicum, whereas C. monspeliensis displayed in the drought plots an opposite dynamic (- 1.23% per year) compared to the natural conditions. During 2010 all monitored species reached the maximum photosynthesis rates in spring, with a depression during summer drought and a recovery after the first Autumn rainfalls. The recovery of the spring rates was almost complete in C. monspeliensis and D. pentaphyllum, while in H. italicum did not exceed the 30% of the spring value. The rainfall exclusion reduced the photosynthesis rates in C. monspeliensis and H. italicum in Autumn. In the control plots the opposite cover trend observed in C. monspeliensis and H.italicum could be

  3. Randomised controlled trial evaluating the short-term analgesic effect of topical diclofenac on chronic Achilles tendon pain: a pilot study.

    Science.gov (United States)

    Bussin, Erin Rebecca; Cairns, Brian; Bovard, Jim; Scott, Alexander

    2017-05-04

    To determine if a topically applied non-steroidal anti-inflammatory drug (diclofenac) can provide short-term pain relief for chronic Achilles tendinopathy (CAT), in order to inform the development of a new rehabilitation protocol. Pilot double-blind, cross-over randomised controlled trial providing participants with tertiary care. The study was conducted at a single research centre in Vancouver, BC. Sixteen adults with unilateral CAT and three adults with bilateral CAT participated. Participants received two successive treatments (10% diclofenac gel or placebo gel) in random order over a 3-day period. There was a 1-week washout period between the treatments. Allocation was by simple randomisation, and the participants as well as the assessing/treating researcher were blinded to treatment allocation. The primary outcome measure was pain level (0-10) during tendon loading (hopping). Secondary outcome measures included pain at rest, pressure pain threshold of the Achilles tendon and symptom improvement. Nineteen adults participated in the study, and all were included in the analysis. Diclofenac gel significantly reduced the average pain during tendon loading (pdiclofenac. Pain at rest was decreased and pressure pain threshold increased with diclofenac treatment, but not with placebo gel. There were no observed or reported side effects of either treatment. In this small, short-term study, diclofenac was able to improve symptoms and reduce pain during tendon loading in participants with CAT, whereas placebo gel was not. A future study of diclofenac as a supplement to rehabilitation, with longer follow-up and powered to detect a difference between diclofenac and placebo, is indicated. ISRCTN60151284, http://www.isrctn.com/ISRCTN60151284 ETHICS: UBC Clinical Research Ethics Board approval was obtained for this research. The certificate number of the ethics certificate of approval to conduct research is H15-00999. © Article author(s) (or their employer(s) unless otherwise

  4. Early and long-term clinical and radiological follow-up results of expanded-polytetrafluoroethylene-covered stent-grafts for transjugular intrahepatic portosystemic shunt procedures

    International Nuclear Information System (INIS)

    Maleux, Geert; Heye, Sam; Thijs, Maria; Wilms, Guy; Nevens, Frederik; Verslype, Chris; Wilmer, Alexander

    2004-01-01

    The purpose of this study was to assess the therapeutic efficacy and immediate and long-term safety of expanded-tetrafluoroethylene covered stent-grafts for transjugular intrahepatic portosystemic shunts in patients with portal hypertension-related complications. A cohort of 56 patients suffering from severe portal hypertension-related complications underwent implantation of an expanded-polytetrafluoroethylene-covered stent-graft. All patients suffered from severe liver cirrhosis graded Child-Pugh A (n=8; 16%), B (n=13; 21%) or C (n=35; 63%). In 44 patients, the stent-graft was placed during the initial TIPS procedure (de novo TIPS); in the other 12 patients, the stent-graft was placed to repermeabilize the previously placed bare stent (TIPS revision). Follow-up was performed with clinical assessment, duplex ultrasound and, if abnormal or inconclusive, with invasive venography and pressure measurements. Per- en immediate post-procedural complications occurred in four patients (4/56, 7%). None of them was lethal. During follow-up, stent occlusion appeared in one patient and stenosis in two; no recurrence of bleeding was noted in all patients treated for variceal bleeding (n=28), and 24 of the 28 patients (86%) suffering from refractory ascites and/or hepatic hydrothorax were free of regular paracenteses and/or drainage of pleural effusion after shunt creation. The 30-day and global mortality for the total study population (n=56) was, respectively, 7% (n=4) and 28.5% (n=16). In the patient subgroup with variceal bleeding (n=28), 30-day mortality was 3.5% (n=1) and global mortality 14.2% (n=4). In the ascites and/or hydrothorax subgroup (n=28), 8.1% (n=3) mortality at 30 days was found and global mortality was 32.4% (n=12). In 10 patients of the 56 studied patients (18%), isolated hepatic encephalopathy occurred, which was lethal in 4 (Child C) patients (7%). Three of these four patients died within the 1st month after TIPS placement. A very high primary patency rate

  5. Early and long-term clinical and radiological follow-up results of expanded-polytetrafluoroethylene-covered stent-grafts for transjugular intrahepatic portosystemic shunt procedures

    Energy Technology Data Exchange (ETDEWEB)

    Maleux, Geert; Heye, Sam; Thijs, Maria; Wilms, Guy [University Hospitals Gasthuisberg, Department of Radiology, Leuven (Belgium); Nevens, Frederik; Verslype, Chris [University Hospitals Gasthuisberg, Department of Hepatology, Leuven (Belgium); Wilmer, Alexander [University Hospitals Gasthuisberg, Department of Medical Intensive Care Unit, Leuven (Belgium)

    2004-10-01

    The purpose of this study was to assess the therapeutic efficacy and immediate and long-term safety of expanded-tetrafluoroethylene covered stent-grafts for transjugular intrahepatic portosystemic shunts in patients with portal hypertension-related complications. A cohort of 56 patients suffering from severe portal hypertension-related complications underwent implantation of an expanded-polytetrafluoroethylene-covered stent-graft. All patients suffered from severe liver cirrhosis graded Child-Pugh A (n=8; 16%), B (n=13; 21%) or C (n=35; 63%). In 44 patients, the stent-graft was placed during the initial TIPS procedure (de novo TIPS); in the other 12 patients, the stent-graft was placed to repermeabilize the previously placed bare stent (TIPS revision). Follow-up was performed with clinical assessment, duplex ultrasound and, if abnormal or inconclusive, with invasive venography and pressure measurements. Per- en immediate post-procedural complications occurred in four patients (4/56, 7%). None of them was lethal. During follow-up, stent occlusion appeared in one patient and stenosis in two; no recurrence of bleeding was noted in all patients treated for variceal bleeding (n=28), and 24 of the 28 patients (86%) suffering from refractory ascites and/or hepatic hydrothorax were free of regular paracenteses and/or drainage of pleural effusion after shunt creation. The 30-day and global mortality for the total study population (n=56) was, respectively, 7% (n=4) and 28.5% (n=16). In the patient subgroup with variceal bleeding (n=28), 30-day mortality was 3.5% (n=1) and global mortality 14.2% (n=4). In the ascites and/or hydrothorax subgroup (n=28), 8.1% (n=3) mortality at 30 days was found and global mortality was 32.4% (n=12). In 10 patients of the 56 studied patients (18%), isolated hepatic encephalopathy occurred, which was lethal in 4 (Child C) patients (7%). Three of these four patients died within the 1st month after TIPS placement. A very high primary patency rate

  6. Key Topics in Sports Medicine

    OpenAIRE

    2006-01-01

    Key Topics in Sports Medicine is a single quick reference source for sports and exercise medicine. It presents the essential information from across relevant topic areas, and includes both the core and emerging issues in this rapidly developing field. It covers: 1) Sports injuries, rehabilitation and injury prevention, 2) Exercise physiology, fitness testing and training, 3) Drugs in sport, 4) Exercise and health promotion, 5) Sport and exercise for special and clinical populations, 6) The ps...

  7. Topics of Bioengineering in Wikipedia

    Directory of Open Access Journals (Sweden)

    Vassia Atanassova

    2009-10-01

    Full Text Available The present report aims to give a snapshot of how topics from the field of bioengineering (bioinformatics, bioprocess systems, biomedical engineering, biotechnology, etc. are currently covered in the free electronic encyclopedia Wikipedia. It also offers insights and information about what Wikipedia is, how it functions, how and when to cite Wikipedian articles, if necessary. Several external wikis, devoted to topics of bioengineering, are also listed and reviewed.

  8. Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial.

    Science.gov (United States)

    Blauvelt, Andrew; de Bruin-Weller, Marjolein; Gooderham, Melinda; Cather, Jennifer C; Weisman, Jamie; Pariser, David; Simpson, Eric L; Papp, Kim A; Hong, H Chih-Ho; Rubel, Diana; Foley, Peter; Prens, Errol; Griffiths, Christopher E M; Etoh, Takafumi; Pinto, Pedro Herranz; Pujol, Ramon M; Szepietowski, Jacek C; Ettler, Karel; Kemény, Lajos; Zhu, Xiaoping; Akinlade, Bolanle; Hultsch, Thomas; Mastey, Vera; Gadkari, Abhijit; Eckert, Laurent; Amin, Nikhil; Graham, Neil M H; Pirozzi, Gianluca; Stahl, Neil; Yancopoulos, George D; Shumel, Brad

    2017-06-10

    Dupilumab (an anti-interleukin-4-receptor-α monoclonal antibody) blocks signalling of interleukin 4 and interleukin 13, type 2/Th2 cytokines implicated in numerous allergic diseases ranging from asthma to atopic dermatitis. Previous 16-week monotherapy studies showed that dupilumab substantially improved signs and symptoms of moderate-to-severe atopic dermatitis with acceptable safety, validating the crucial role of interleukin 4 and interleukin 13 in atopic dermatitis pathogenesis. We aimed to evaluate the long-term efficacy and safety of dupilumab with medium-potency topical corticosteroids versus placebo with topical corticosteroids in adults with moderate-to-severe atopic dermatitis. In this 1-year, randomised, double-blinded, placebo-controlled, phase 3 study (LIBERTY AD CHRONOS), adults with moderate-to-severe atopic dermatitis and inadequate response to topical corticosteroids were enrolled at 161 hospitals, clinics, and academic institutions in 14 countries in Europe, Asia-Pacific, and North America. Patients were randomly assigned (3:1:3) to subcutaneous dupilumab 300 mg once weekly (qw), dupilumab 300 mg every 2 weeks (q2w), or placebo via a central interactive voice/web response system, stratified by severity and global region. All three groups were given concomitant topical corticosteroids with or without topical calcineurin inhibitors where inadvisable for topical corticosteroids. Topical corticosteroids could be tapered, stopped, or restarted on the basis of disease activity. Coprimary endpoints were patients (%) achieving Investigator's Global Assessment (IGA) 0/1 and 2-point or higher improvement from baseline, and Eczema Area and Severity Index 75% improvement from baseline (EASI-75) at week 16. Week 16 efficacy and week 52 safety analyses included all randomised patients; week 52 efficacy included patients who completed treatment by US regulatory submission cutoff. This study is registered with ClinicalTrials.gov, NCT02260986. Between Oct 3, 2014

  9. Topics in lightwave transmission systems

    CERN Document Server

    Li, Tingye

    1991-01-01

    Topics in Lightwave Transmission Systems is a second volume of a treatise on optical fiber communications that is devoted to the science, engineering, and application of information transmission via optical fibers. The first volume, published in 1985, dealt exclusively with fiber fabrication. The present volume contains topics that pertain to subsystems and systems. The book contains five chapters and begins with discussions of transmitters and receivers, which are basic to systems now operating in the field. Subsequent chapters cover topics relating to coherent systems: frequency and phase m

  10. Benthic Cover

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Benthic cover (habitat) maps are derived from aerial imagery, underwater photos, acoustic surveys, and data gathered from sediment samples. Shallow to moderate-depth...

  11. Long-term use of a new topical formulation containing piroxicam 0.8% and sunscreen: efficacy and tolerability on actinic keratosis. A proof of concept study.

    Science.gov (United States)

    Babino, Graziella; Diluvio, Laura; Bianchi, Luca; Orlandi, Augusto; Di Prete, Monia; Chimenti, Sergio; Milani, Massimo; Campione, Elena

    2016-08-01

    Cyclooxygenase (COX) 1 and 2 enzyme up-regulation is involved in the pathogenetic process of actinic keratosis (A.K.) and non-melanoma skin cancers. Diclofenac, a non-steroidal anti-inflammatory (N.S.A.I.D.) drug, is used as topical treatment of A.K. Piroxicam is a N.S.A.I.D. characterized by a high COX-1 inhibition activity. We conducted an 18 month exploratory open-label study on A.K., to assess the efficacy and tolerability of a new topical formulation of piroxicam and sunscreen in A.K. Enrolled subjects applied a galenic formulation of piroxicam 0.8%, vehiculated in a topical product containing sun filters with high (50+) and broad spectrum (UVA) actions, twice a day for 6 months. Subjects were then followed up for additional 12 months. Thirty-eight subjects with a total of 69 A.K. lesions participated in the trial. The primary outcome was the evolution of the Actinic Keratosis Erythema Scale Atrophy (A.K.E.S.A) score assessing erythema, scale, and atrophy of a target A.K. lesion. Secondary outcomes were the percentage of treated lesions with complete (100%) or partial (≥75%) clearance and the evaluation skin tolerability. A.K.E.S.A. mean (S.D.) score at baseline was 7.5 (1.2). After 6 months of treatment, A.K.E.S.A. score decreased to 0.9 (1.1), a -88% reduction versus baseline. At the end of follow-up, A.K.E.S.A. score was 0.8 (1.2). A complete response was achieved in 38 of the 69 lesions (55%, 95% C.I.: 43% to 66%) and clearance was maintained 1 year post-treatment. A partial clearance was observed in 57 of 69 treated lesions (83%, 95% C.I.: 73% to 91%). Adverse events were limited to mild local irritation. Our experience suggests that 6 month topical piroxicam 0.8% is efficacious and well tolerated in A.K. Clinical efficacy is maintained 1 year post-treatment. The main limitation of our study is that it was an open label non-controlled trial. Future controlled trials are warranted in order to compare the efficacy and tolerability of this topical

  12. Modeling the long-term effect of winter cover crops on nitrate transport in artificially drained fields across the Midwest U.S.

    Science.gov (United States)

    A fall-planted cover crop is a management practice with multiple benefits including reducing nitrate losses from artificially drained fields. We used the Root Zone Water Quality Model (RZWQM) to simulate the impact of a cereal rye cover crop on reducing nitrate losses from drained fields across five...

  13. Topics in Bioethics: A Development of Student Perspectives

    Directory of Open Access Journals (Sweden)

    Keith A. Johnson

    2014-10-01

    Full Text Available Exposing students to current biotechnological and medical issues is eye-opening for many students in a way that is not always achieved through lecture-based learning. Lecture or investigative teaching styles provide a tremendous knowledge base for the students, but sometimes these teaching styles do not allow the student to fully develop, especially personal attitudes to issues in bioethics. Through online videos, Hollywood movies, guided readings and classroom discussions, students in this course are informed of some bioethical topics, encouraged to learn about other topics, and use this gained knowledge to develop personal positions regarding the value and/or risk of the issues. This course has been well-received by previous students as a favorite in terms of both topics covered and style.

  14. Long-term cover design for low-level radioactive and hazardous waste sites as applied to the Rocky Flats Environmental Technology Site solar evaporation ponds

    International Nuclear Information System (INIS)

    Stenseng, S.E.; Nixon, P.A.

    1996-01-01

    The US Department of Energy (DOE) operated five lined solar evaporation ponds (SEPs) at the Rocky Flats Environmental Technology Site (RFETS) in Jefferson County, Colorado from 1953 until 1986. The SEPs were used primarily to store and evaporate low-level radioactive and hazardous process wastes. Operation of the SEPs has resulted in contamination of the surrounding soils, and may also provide a source of groundwater contamination. The DOE proposes to close the SEPs by consolidating the contaminated material beneath an engineered cover. The primary objective of the closure of such hazardous and radioactive sites is to limit the exposure of the general public to the contaminants for time periods ranging from 100 to 10,000 years. The goal of the SEPs engineered cover is to isolate hazardous and low-level radioactive soils for a minimum of 1,000 years. Since there is currently no existing regulatory design guidance for a 1,000-year engineered cover, the proposed design of the SEPs engineered cover is based on research and testing that has been conducted for many years at various DOE facilities in the US. This paper discusses the main design theories of the proposed engineered cover for the closure of the SEPs, and how the research and test results of these other programs have been used to arrive at the final cover configuration, the material selections, the component layering, layer thicknesses, and the balance and interaction between components to establish an overall effective cover system

  15. Section 608 Technician Certification Test Topics

    Science.gov (United States)

    Identifies some of the topics covered on Section 608 Technician Certification tests such as ozone depletion, the Clean Air Act and Montreal Protocol, Substitute Refrigerants and oils, Refrigeration and Recovery Techniques.

  16. Topics in current aerosol research

    CERN Document Server

    Hidy, G M

    1971-01-01

    Topics in Current Aerosol Research deals with the fundamental aspects of aerosol science, with emphasis on experiment and theory describing highly dispersed aerosols (HDAs) as well as the dynamics of charged suspensions. Topics covered range from the basic properties of HDAs to their formation and methods of generation; sources of electric charges; interactions between fluid and aerosol particles; and one-dimensional motion of charged cloud of particles. This volume is comprised of 13 chapters and begins with an introduction to the basic properties of HDAs, followed by a discussion on the form

  17. Mental Mechanisms for Topics Identification

    Directory of Open Access Journals (Sweden)

    Louis Massey

    2014-01-01

    Full Text Available Topics identification (TI is the process that consists in determining the main themes present in natural language documents. The current TI modeling paradigm aims at acquiring semantic information from statistic properties of large text datasets. We investigate the mental mechanisms responsible for the identification of topics in a single document given existing knowledge. Our main hypothesis is that topics are the result of accumulated neural activation of loosely organized information stored in long-term memory (LTM. We experimentally tested our hypothesis with a computational model that simulates LTM activation. The model assumes activation decay as an unavoidable phenomenon originating from the bioelectric nature of neural systems. Since decay should negatively affect the quality of topics, the model predicts the presence of short-term memory (STM to keep the focus of attention on a few words, with the expected outcome of restoring quality to a baseline level. Our experiments measured topics quality of over 300 documents with various decay rates and STM capacity. Our results showed that accumulated activation of loosely organized information was an effective mental computational commodity to identify topics. It was furthermore confirmed that rapid decay is detrimental to topics quality but that limited capacity STM restores quality to a baseline level, even exceeding it slightly.

  18. Long-term temporal variability of the radon-222 exhalation flux from a landform covered by low uranium grade waste rock

    International Nuclear Information System (INIS)

    Bollhöfer, Andreas; Doering, Che

    2016-01-01

    Radon-222 exhalation flux densities from two different substrates of several metres thickness, waste rock and waste rock mixed with approximately 30% lateritic material, were measured over a period of five years in the wet-dry tropics of Northern Australia. Fourteen measurement campaigns using activated charcoal canisters (n > 1000) covered both dry and wet seasons and showed differences in seasonal and long term trends of the "2"2"2Rn exhalation flux densities normalised to the "2"2"6Ra activity concentrations of the substrate. Dry season "2"2"2Rn exhalation was generally higher for the mixed substrate, due to the larger fraction of fines. Seasonality established within the first year of landform construction on the mixed substrate, due to the higher water holding capacity of the lateritic material. In contrast, waste rock only shows no seasonality until years four and five after construction, when average normalised dry season "2"2"2Rn exhalation flux densities from waste rock increase to values (0.47 ± 0.06 mBq m"−"2 s"−"1 per Bq kg"−"1) similar to the mixed substrate (0.64 ± 0.08 mBq m"−"2 s"−"1 per Bq kg"−"1), likely due to an increase in fines from rapid weathering of the schistose waste rock. Volumetric water content has been used to parametrize relative "2"2"2Rn exhalation and we determined that wet season "2"2"2Rn exhalation is about 40% of the dry season exhalation. - Highlights: • We determined "2"2"2Rn exhalation flux densities normalised to "2"2"6Ra activity concentrations (R_E_-_R) for two substrates. • R_E_-_R was lower for waste rock only compared to waste rock blended with 30% fine grained lateritic material. • Seasonality in waste rock "2"2"2Rn exhalation flux densities established 4 years after construction. • Wet season R_E_-_R was about 40% of the dry season R_E_-_R.

  19. Topical report on release scenario analysis of long-term management of high-level defense waste at the Hanford Site

    International Nuclear Information System (INIS)

    Wallace, R.W.; Landstrom, D.K.; Blair, S.C.; Howes, B.W.; Robkin, M.A.; Benson, G.L.; Reisenauer, A.E.; Walters, W.H.; Zimmerman, M.G.

    1980-11-01

    Potential release scenarios for the defense high-level waste (HLW) on the Hanford Site are presented. Presented in this report are the three components necessary for evaluating the various alternatives under consideration for long-term management of Hanford defense HLW: identification of scenarios and events which might directly or indirectly disrupt radionuclide containment barriers; geotransport calculations of waste migration through the site media; and consequence (dose) analyses based on groundwater and air pathways calculations. The scenarios described in this report provide the necessary parameters for radionuclide transport and consequence analysis. Scenarios are categorized as either bounding or nonbounding. Bounding scenarios consider worst case or what if situations where an actual and significant release of waste material to the environment would happen if the scenario were to occur. Bounding scenarios include both near-term and long-term scenarios. Near-term scenarios are events which occur at 100 years from 1990. Long term scenarios are potential events considered to occur at 1000 and 10,000 years from 1990. Nonbounding scenarios consider events which result in insignificant releases or no release at all to the environment. Three release mechanisms are described in this report: (1) direct exposure of waste to the biosphere by a defined sequence of events (scenario) such as human intrusion by drilling; (2) radionuclides contacting an unconfined aquifer through downward percolation of groundwater or a rising water table; and (3) cataclysmic or explosive release of radionuclides by such mechanisms as meteorite impact, fire and explosion, criticality, or seismic events. Scenarios in this report present ways in which these release mechanisms could occur at a waste management facility. The scenarios are applied to the two in-tank waste management alternatives: in-situ disposal and continued present action

  20. Hot Topics/New Initiatives | Drinking Water in New England ...

    Science.gov (United States)

    2017-07-06

    Information on Drinking Water in New England. Major Topics covered include: Conservation, Private Wells, Preventing Contamination, Drinking Water Sources, Consumer Confidence Reports, and Drinking Water Awards.

  1. Sganzerla Cover

    Directory of Open Access Journals (Sweden)

    Victor da Rosa

    2014-06-01

    Full Text Available Neste artigo, realizo uma leitura do cinema de Rogério Sganzerla, desde o clássico O bandido da luz vermelha até os documentários filmados na década de oitenta, a partir de duas noções centrais: cover e over. Para isso, parto de uma controvérsia com o ensaio de Ismail Xavier, Alegorias do subdesenvolvimento, em que o crítico realiza uma leitura do cinema brasileiro da década de sessenta através do conceito de alegoria; depois releio uma série de textos críticos do próprio Sganzerla, publicados em Edifício Sganzerla, procurando repensar as ideias de “herói vazio” ou “cinema impuro” e sugerindo assim uma nova relação do seu cinema com o tempo e a representação; então busco articular tais ideias com certos procedimentos de vanguarda, como a falsificação, a cópia, o clichê e a colagem; e finalmente procuro mostrar que, no cinema de Sganzerla, a partir principalmente de suas reflexões sobre Orson Welles, a voz é usada de maneira a deformar a interpretação naturalista.

  2. 20 years of long-term water balance measurements of a landfill cover system with components constructed from pre-treated dredged material

    NARCIS (Netherlands)

    Berger, K.; Groengroeft, A.; Gebert, J.; Harms, C.; Eschenbach, A.

    2017-01-01

    The cover system of the mono-landfill Hamburg-Francop for disposal of dredged
    material comprises a mineral liner of pre-treated fine-grained dredged material (‘METHAmaterial’) and an overlying drainage layer of pre-treated sandy dredged material (‘METHAsand’). Water balance and effectiveness of

  3. Causes and consequences of short-term sea-level changes in the Cretaceous green- and "hothouse": Topics and context of IGCP Project 609

    Science.gov (United States)

    Sames, Benjamin; Wagreich, Michael

    2015-04-01

    In contrast to the well-understood process of glacial eustasy, controlled mainly by waxing and waning of continental ice sheets, significant short-term, i.e. 10s kyr to a few myr (3rd to 4th order cycles) sea-level changes during the Cretaceous major greenhouse episode remain enigmatic. Such cyclic changes are often explained by the presence of ephemeral ice sheets even during the hottest greenhouse phases ("hothouse periods"), such as the mid-Cretaceous. Though Cretaceous global eustasy involves processes like brief glacial episodes (glacio-eustasy) for which evidence was given - at least for the Early Cretaceous and the late Late Cretaceous - other mechanisms have to be taken into consideration for the "hothouse periods" during which continental ice shields are highly improbable, like the storage and release of groundwater (termed "limno-eustasy" or "aquifer-eustasy"), the possible effect and magnitude of which might have been highly underestimated. Investigation of the timing, the causes, and the consequences of significant short-term (i.e. mainly kyr to 100s of kyr) sea-level changes during the last major greenhouse episode of Earth history, the Cretaceous, is the ultimate goal of the UNESCO IGCP (International Geoscience Programme) project number 609 "Climate-environmental deteriorations during greenhouse phases: Causes and consequences of short-term Cretaceous sea-level changes" (2013-2017; http://www.univie.ac.at/igcp609/). This also comprises the global versus regional correlation and extent of the sequences, their cyclicities, as well as the processes and triggering mechanisms for these, and marine to non-marine correlations. Recent refinements of the geological time scale have made major advances for the Cretaceous to yield a resolution comparable to that of younger Earth history. It is now for the first time possible to correlate and date short-term Cretaceous sea-level records with a resolution appropriate for their detailed analysis. Recognized

  4. Topics in field theory

    International Nuclear Information System (INIS)

    Velasco, E.S.

    1986-01-01

    This dissertation deals with several topics of field theory. Chapter I is a brief outline of the work presented in the next chapters. In chapter II, the Gauss-Bonnet-Chern theorem for manifolds with boundary is computed using the path integral representation of the Witten index for supersymmetric quantum mechanical systems. In chapter III the action of N = 2 (Poincare) supergravity is obtained in terms of N = 1 superfields. In chapter IV, N = 2 supergravity coupled to the (abelian) vector multiplet is projected into N - 1 superspace. There, the resulting set of constraints is solved in terms of unconstrained prepotential and the action in terms of N = 1 superfields is constructed. In chapter V the set of constraints for N = 2 conformal supergravity is projected into N = 1 superspace and solved in terms of N = 1 conformal supergravity fields a d matter prepotentials. In chapter VI the role of magnetic monopoles in the phase structure of the change one fixed length abelian Higgs model ins the latticer is investigated using analytic and numerical methods. The technique of monopole suppression is used to determine the phase transition lines that are monopole driven. Finally in chapter VII, the role of the charge of the Higgs field in the abelian Higgs model in the lattice is investigated

  5. Topical report review status

    International Nuclear Information System (INIS)

    1997-08-01

    This report provides industry with procedures for submitting topical reports, guidance on how the U.S. Nuclear Regulatory Commission (NRC) processes and responds to topical report submittals, and an accounting, with review schedules, of all topical reports currently accepted for review schedules, of all topical reports currently accepted for review by the NRC. This report will be published annually. Each sponsoring organization with one or more topical reports accepted for review copies

  6. Topical nonsteroidal anti-inflammatory drugs for the treatment of pain due to soft tissue injury: diclofenac epolamine topical patch

    Directory of Open Access Journals (Sweden)

    David R Lionberger

    2010-11-01

    Full Text Available David R Lionberger1, Michael J Brennan21Southwest Orthopedic Group, Houston, TX, USA; 2Department of Medicine, Bridgeport Hospital, Bridgeport, CT, USAAbstract: The objective of this article is to review published clinical data on diclofenac epolamine topical patch 1.3% (DETP in the treatment of acute soft tissue injuries, such as strains, sprains, and contusions. Review of published literature on topical nonsteroidal anti-inflammatory drugs (NSAIDs, diclofenac, and DETP in patients with acute soft tissue injuries was included. Relevant literature was identified on MEDLINE using the search terms topical NSAIDs, diclofenac, diclofenac epolamine, acute pain, sports injury, soft tissue injury, strain, sprain, and contusion, and from citations in retrieved articles covering the years 1978–2008. Review of published, randomized clinical trials and meta-analyses shows that topical NSAIDs are significantly more effective than placebo in relieving acute pain; the pooled average relative benefit was 1.7 (95% confidence interval, 1.5–1.9. In a limited number of comparisons, topical and oral NSAIDs provided comparable pain relief, but the use of topical agents produced lower plasma drug concentrations and fewer systemic adverse events (AEs. The physical–chemical properties of diclofenac epolamine make it well suited for topical use. In patients with acute soft tissue injuries treated with DETP, clinical data report an analgesic benefit within hours of the first application, and significant pain relief relative to placebo within 3 days. Moreover, DETP displayed tolerability comparable with placebo; the most common AEs were pruritus and other application site reactions. Review of published literature suggests that DETP is generally safe and well tolerated, clinically efficacious, and a rational treatment option for patients experiencing acute pain associated with strains, sprains, and contusions, and other localized painful conditions

  7. In Vivo Short-Term Topical Application of BAY 11-7082 Prevents the Acidic Bile–Induced mRNA and miRNA Oncogenic Phenotypes in Exposed Murine Hypopharyngeal Mucosa

    Directory of Open Access Journals (Sweden)

    Clarence T. Sasaki

    2018-04-01

    Full Text Available PURPOSE: Bile-containing gastroesophageal reflux may promote cancer at extraesophageal sites. Acidic bile can accelerate NF-κB activation and molecular events, linked to premalignant changes in murine hypopharyngeal mucosa (HM. We hypothesize that short-term in vivo topical application of NF-κB inhibitor BAY 11-7082 can prevent acidic bile–induced early preneoplastic molecular events, suggesting its potential role in disease prevention. EXPERIMENTAL DESIGN: We topically exposed HM (C57Bl/6j wild-type to a mixture of bile acids at pH 3.0 with and without BAY 11-7082 3 times/day for 7 days. We used immunofluorescence, Western blotting, immunohistochemistry, quantitative polymerase chain reaction, and polymerase chain reaction microarrays to identify NF-κB activation and its associated oncogenic mRNA and miRNA phenotypes, in murine hypopharyngeal cells in vitro and in murine HM in vivo. RESULTS: Short-term exposure of HM to acidic bile is a potent stimulus accelerating the expression of NF-κB signaling (70 out of 84 genes and oncogenic molecules. Topical application of BAY 11-7082 sufficiently blocks the effect of acidic bile. BAY 11-7082 eliminates NF-κB activation in regenerating basal cells of acidic bile–treated HM and prevents overexpression of molecules central to head and neck cancer, including bcl-2, STAT3, EGFR, TNF-α, and WNT5A. NF-κB inhibitor reverses the upregulated “oncomirs” miR-155 and miR-192 and the downregulated “tumor suppressors” miR-451a and miR-375 phenotypes in HM affected by acidic bile. CONCLUSION: There is novel evidence that acidic bile–induced NF-κB–related oncogenic mRNA and miRNA phenotypes are generated after short-term 7-day mucosal exposure and that topical mucosal application of BAY 11-7082 can prevent the acidic bile–induced molecular alterations associated with unregulated cell growth and proliferation of hypopharyngeal cells.

  8. Evaluating topic models with stability

    CSIR Research Space (South Africa)

    De Waal, A

    2008-11-01

    Full Text Available Topic models are unsupervised techniques that extract likely topics from text corpora, by creating probabilistic word-topic and topic-document associations. Evaluation of topic models is a challenge because (a) topic models are often employed...

  9. Mineralogical and geochemical characterization of the Old Tailings Dam, Australia: Evaluating the effectiveness of a water cover for long-term AMD control

    International Nuclear Information System (INIS)

    Jackson, Laura M.; Parbhakar-Fox, Anita

    2016-01-01

    Establishing a shallow water cover over tailings deposited in a designated storage facility is one option to limit oxygen diffusion and retard oxidation of sulfides which have the potential to form acid mine drainage (AMD). The Old Tailings Dam (OTD) located at the Savage River mine, western Tasmania contains 38 million tonnes of pyritic tailings deposited from 1967 to 1982, and is actively generating AMD. The OTD was constructed on a natural gradient, resulting in sub-aerial exposure of the southern area, with the northern area under a natural water cover. This physical contrast allowed for the examination of tailings mineralogy and geochemistry as a function of water cover depth across the OTD. Tailings samples (n = 144, depth: ≤ 1.5 m) were collected and subjected to a range of geochemical and mineralogical evaluations. Tailings from the southern and northern extents of the OTD showed similar AMD potential based on geochemical (NAG pH range: 2.1 to 4.2) and bulk mineralogical parameters, particularly at depth. However, sulfide alteration index (SAI) assessments highlighted the microscale contrast in oxidation. In the sub-aerial zone pyrite grains are moderately oxidized to a depth of 0.3 m (maximum SAI of 6/10), under both gravel fill and oxidized covers, with secondary minerals (e.g., ferrihydrite and goethite) developed along rims and fractures. Beneath this, mildly oxidized pyrite is seen in fresh tailings (SAI = 2.9/10 to 5.8/10). In the sub-aqueous zone, the degree of pyrite oxidation demonstrates a direct relationship with cover depth, with unoxidized, potentially reactive tailings identified from 2.5 m, directly beneath an organic-rich sediment layer (SAI = 0 to 1/10). These findings are broadly similar to other tailings storage facilities e.g., Fox Lake, Sherritt-Gordon Zn−Cu mine, Canada and Stekenjokk mine, Sweden where water covers up to 2 m have successfully reduced AMD. Whilst geotechnical properties of the OTD restrict the extension

  10. Topic prominence in Chinese EFL learners’ interlanguage

    Directory of Open Access Journals (Sweden)

    Shaopeng Li

    2014-01-01

    Full Text Available The present study aims to investigate the general characteristics of topicprominent typological interlanguage development of Chinese learners of English in terms of acquiring subject-prominent English structures from a discourse perspective. Topic structures mainly appear in Chinese discourse in the form of topic chains (Wang, 2002; 2004. The research target are the topic chain, which is the main topic-prominent structure in Chinese discourse, and zero anaphora, which is the most common topic anaphora in the topic chain. Two important findings emerged from the present study. First, the characteristics of Chinese topic chains are transferrable to the interlanguage of Chinese EFL learners, thus resulting in overgeneralization of the zero anaphora. Second, the interlanguage discourse of Chinese EFL learners reflects a change of the second language acquisition process from topic-prominence to subject-prominence, thus lending support to the discourse transfer hypothesis.

  11. Women's Health Topics

    Science.gov (United States)

    ... Information by Audience For Women Women's Health Topics Women's Health Topics Share Tweet Linkedin Pin it More sharing options Linkedin Pin it Email Print National Women's Health Week May 13 - 19, 2018 Join us ...

  12. Regulatory Information By Topic

    Science.gov (United States)

    EPA develops and enforces regulations that span many environmental topics, from acid rain reduction to wetlands restoration. Each topic listed below may include related laws and regulations, compliance enforcement information, policies guidance

  13. Link between Research, Development and Demonstration (RD and D) and Stakeholder Confidence: the Specific Aspect of Long-term Safety. Proceedings of a Topical Session, Issy-les-Moulineaux, France 6-8 June 2007

    International Nuclear Information System (INIS)

    2008-01-01

    The Forum on Stakeholder Confidence (FSC) was created under a mandate from the OECD Nuclear Energy Agency's Radioactive Waste Management Committee (RWMC) to facilitate the sharing of international experience in addressing the societal dimension of radioactive waste management. It explores means of ensuring an effective dialogue with the public, and considers ways to strengthen confidence in decision-making processes. NEA member countries nominate participants. The FSC today includes representatives of national regulators, implementing agencies, policy makers, and R and D scientists from 16 OECD countries and two international organisations. Each has experience in and/or responsibility for stakeholder interaction. The Forum was launched in August 2000, in Paris, and convenes a series of alternating regular meetings and workshops. The FSC is expected to identify specific issues of interest on which stakeholders can learn from one another and provide a platform for discussing and exchanging those issues. This topical session's emphasis on long-term safety is meant to complement the Programme of Work of the RWMC in this area and to create a bridge between the FSC and the more technically oriented groups of the RWMC, e.g., the Integration Group for the Safety Case (IGSC) and the Regulators' Forum. These Proceedings are meant to provide a record that can be used by a wide spectrum of stakeholders and decision-makers. They include: a) An executive summary of the topical presentations, and of the discussion they sparked within the FSC; b) Texts and Power Point presentations provided by the speakers at the Topical Session

  14. Freshman Health Topics

    Science.gov (United States)

    Hovde, Karen

    2011-01-01

    This article examines a cluster of health topics that are frequently selected by students in lower division classes. Topics address issues relating to addictive substances, including alcohol and tobacco, eating disorders, obesity, and dieting. Analysis of the topics examines their interrelationships and organization in the reference literature.…

  15. Topical nonsteroidal anti-inflammatory drugs for the treatment of pain due to soft tissue injury: diclofenac epolamine topical patch.

    Science.gov (United States)

    Lionberger, David R; Brennan, Michael J

    2010-11-10

    The objective of this article is to review published clinical data on diclofenac epolamine topical patch 1.3% (DETP) in the treatment of acute soft tissue injuries, such as strains, sprains, and contusions. Review of published literature on topical nonsteroidal anti-inflammatory drugs (NSAIDs), diclofenac, and DETP in patients with acute soft tissue injuries was included. Relevant literature was identified on MEDLINE using the search terms topical NSAIDs, diclofenac, diclofenac epolamine, acute pain, sports injury, soft tissue injury, strain, sprain, and contusion, and from citations in retrieved articles covering the years 1978-2008. Review of published, randomized clinical trials and meta-analyses shows that topical NSAIDs are significantly more effective than placebo in relieving acute pain; the pooled average relative benefit was 1.7 (95% confidence interval, 1.5-1.9). In a limited number of comparisons, topical and oral NSAIDs provided comparable pain relief, but the use of topical agents produced lower plasma drug concentrations and fewer systemic adverse events (AEs). The physical-chemical properties of diclofenac epolamine make it well suited for topical use. In patients with acute soft tissue injuries treated with DETP, clinical data report an analgesic benefit within hours of the first application, and significant pain relief relative to placebo within 3 days. Moreover, DETP displayed tolerability comparable with placebo; the most common AEs were pruritus and other application site reactions. Review of published literature suggests that DETP is generally safe and well tolerated, clinically efficacious, and a rational treatment option for patients experiencing acute pain associated with strains, sprains, and contusions, and other localized painful conditions.

  16. Long-term agricultural land-cover change and potential for cropland expansion in the former Virgin Lands area of Kazakhstan

    DEFF Research Database (Denmark)

    Kraemer, Roland; Prishchepov, Alexander; Müller, Daniel

    2015-01-01

    of Northern Kazakhstan. Further, we assessed the potential of currently idle cropland for re-cultivation. We reconstructed the cropland extent before and after the Virgin Lands Campaign using archival maps, and we mapped the agricultural land cover in the late Soviet and post-Soviet period using multi...... until 1990, as well as cropland contraction after 1990, occurred mainly in areas that were less favorable for agriculture. Cropland re-cultivation after 2000 was occurring on lands with relatively favorable agro-environmental conditions in comparison to remaining idle croplands, albeit with much lower...... agro-environmental endowment compared to stable croplands from 1990 to 2010. In sum, we found that cropland production potentials of the currently uncultivated areas are much lower than commonly believed, and further cropland expansion is only possible at the expense of marginal lands. Our results...

  17. Evaluation of the Effects of Temporary Covered Nitinol Stent Placement in the Prostatic Urethra: Short-Term Study in the Canine Model

    International Nuclear Information System (INIS)

    Crisostomo, Veronica; Song, Ho Young; Maynar, Manuel; Sun, Fei; Soria, Federico; Lima, Juan Rafael; Yoon, Chang Jin; Uson-Gargallo, Jesus

    2007-01-01

    Purpose. To evaluate the effect of temporary stent placement on the canine prostatic urethra. Methods. Retrievable PTFE-covered nitinol stents were placed in the prostatic urethras of 8 beagle dogs under fluoroscopic guidance. Retrograde urethrography was obtained before and after stenting. Retrograde urethrography and endoscopy were performed 1 and 2 months after deployment. The endoscopic degree of hyperplasia was rated on a scale of 0 to 4 (0 absence, 4 = occlusion). On day 60, stents were removed and urethrography was performed immediately before euthanasia. Pathologic analysis was performed to determine the degree of glandular atrophy, periurethral fibrosis, and urethral dilation. Results. Stent deployment was technically successful in 7 animals, and failed in 1 dog due to a narrow urethral lumen. Complete migration was seen in 2 animals at 1 month, and an additional stent was deployed. On day 30, endoscopy showed slight hyperplasia (grade 1) in 3 animals. On day 60, moderate hyperplasia (grade 2) was evidenced in 4 cases. No impairment of urinary flow was seen during follow-up. Retrieval was technically easy to perform, and was successful in all dogs. The major histologic findings were chronic inflammatory cell infiltrates; prostate glandular atrophy, with a mean value of 1.86 (SD 0.90); periurethral fibrosis, with a mean ratio of 29.37 (SD 10.41); and dilatation of the prostatic urethra, with a mean ratio of 6.75 (SD 3.22). Conclusion. Temporary prostatic stent placement in dogs is safe and feasible, causing marked enlargement of the prostatic urethral lumen. Retrievable covered stents may therefore be an option for bladder outlet obstruction management in men

  18. Topical beta-blockers and mortality

    NARCIS (Netherlands)

    Müskens, Rogier P. H. M.; Wolfs, Roger C. W.; Witteman, Jacqueline C. M.; Hofman, Albert; de Jong, Paulus T. V. M.; Stricker, Bruno H. C.; Jansonius, Nomdo M.

    2008-01-01

    To study the associations between long-term and short-term use of topical beta-blockers and mortality. Prospective population-based cohort study. To examine long-term effects, 3842 participants aged 55 years and older were recruited. To examine short-term effects, 484 incident beta-blocker users and

  19. Topical beta-Blockers and Mortality

    NARCIS (Netherlands)

    Muskens, Rogier P. H. M.; Wolfs, Roger C. W.; Wittenian, Jacqueline C. M.; Hofman, Albert; de Jong, Paulus T. V. M.; Stricker, Bruno H. C.; Jansonius, Nomdo M.

    Purpose: To study the associations between long-term and short-term use of topical beta-blockers and mortality. Design: Prospective population-based cohort study. Participants: To examine long-term effects, 3842 participants aged 55 years and older were recruited. To examine short-term effects, 484

  20. Syntacticized topics in Kurmuk

    DEFF Research Database (Denmark)

    Andersen, Torben

    2015-01-01

    This article argues that Kurmuk, a little-described Western Nilotic language, is characterized by a syntacticized topic whose grammatical relation is variable. In this language, declarative clauses have as topic an obligatory preverbal NP which is either a subject, an object or an adjunct....... The grammatical relation of the topic is expressed by a voice-like inflection of the verb, here called orientation. While subject-orientation is morphologically unmarked, object-oriented and adjunct-oriented verbs are marked by a subject suffix or by a suffix indicating that the topic is not subject, and adjunct......-orientation differs from object-orientation by a marked tone pattern. Topic choice largely reflects information structure by indicating topic continuity. The topic also plays a crucial role in relative clauses and in clauses with contrastive constituent focus, in that objects and adjuncts can only be relativized...

  1. Associations between soil bacterial community structure and nutrient cycling functions in long-term organic farm soils following cover crop and organic fertilizer amendment.

    Science.gov (United States)

    Fernandez, Adria L; Sheaffer, Craig C; Wyse, Donald L; Staley, Christopher; Gould, Trevor J; Sadowsky, Michael J

    2016-10-01

    Agricultural management practices can produce changes in soil microbial populations whose functions are crucial to crop production and may be detectable using high-throughput sequencing of bacterial 16S rRNA. To apply sequencing-derived bacterial community structure data to on-farm decision-making will require a better understanding of the complex associations between soil microbial community structure and soil function. Here 16S rRNA sequencing was used to profile soil bacterial communities following application of cover crops and organic fertilizer treatments in certified organic field cropping systems. Amendment treatments were hairy vetch (Vicia villosa), winter rye (Secale cereale), oilseed radish (Raphanus sativus), buckwheat (Fagopyrum esculentum), beef manure, pelleted poultry manure, Sustane(®) 8-2-4, and a no-amendment control. Enzyme activities, net N mineralization, soil respiration, and soil physicochemical properties including nutrient levels, organic matter (OM) and pH were measured. Relationships between these functional and physicochemical parameters and soil bacterial community structure were assessed using multivariate methods including redundancy analysis, discriminant analysis, and Bayesian inference. Several cover crops and fertilizers affected soil functions including N-acetyl-β-d-glucosaminidase and β-glucosidase activity. Effects, however, were not consistent across locations and sampling timepoints. Correlations were observed among functional parameters and relative abundances of individual bacterial families and phyla. Bayesian analysis inferred no directional relationships between functional activities, bacterial families, and physicochemical parameters. Soil functional profiles were more strongly predicted by location than by treatment, and differences were largely explained by soil physicochemical parameters. Composition of soil bacterial communities was predictive of soil functional profiles. Differences in soil function were

  2. Modern topics in electron scattering

    CERN Document Server

    Frois, Bernard

    1991-01-01

    This book summarizes the considerable progress recently achieved in the understanding of nucleon and nuclear structure by using high energy electrons as a probe. A collection of papers discusses in detail the new frontiers of this field. Experimental and theoretical articles cover topics such as the structure of the nucleon, nucleon distributions, many-body correlations, non-nucleonic degrees of freedom and few-body systems. This book is an up-to-date introduction to the research planned with continuous beam electron accelerators.

  3. Long-Term Hydrologic Impact Assessment of Non-point Source Pollution Measured Through Land Use/Land Cover (LULC) Changes in a Tropical Complex Catchment

    Science.gov (United States)

    Abdulkareem, Jabir Haruna; Sulaiman, Wan Nor Azmin; Pradhan, Biswajeet; Jamil, Nor Rohaizah

    2018-05-01

    The contribution of non-point source pollution (NPS) to the contamination of surface water is an issue of growing concern. Non-point source (NPS) pollutants are of various types and altered by several site-specific factors making them difficult to control due to complex uncertainties involve in their behavior. Kelantan River basin, Malaysia is a tropical catchment receiving heavy monsoon rainfall coupled with intense land use/land cover (LULC) changes making the area consistently flood prone thereby deteriorating the surface water quality in the area. This study was conducted to determine the spatio-temporal variation of NPS pollutant loads among different LULC changes and to establish a NPS pollutant loads relationships among LULC conditions and sub-basins in each catchment. Four pollutants parameters such as total suspended solids (TSS), total phosphorus (TP), total nitrogen (TN) and ammonia nitrogen (AN) were chosen with their corresponding event mean concentration values (EMC). Soil map and LULC change maps corresponding to 1984, 2002 and 2013 were used for the calculation of runoff and NPS pollutant loads using numeric integration in a GIS environment. Analysis of Variance (ANOVA) was conducted for the comparison of NPS pollutant loads among the three LULC conditions used and the sub-basins in each catchment. The results showed that the spatio-temporal variation of pollutant loads in almost all the catchments increased with changes in LULC condition as one moves from 1984 to 2013, with 2013 LULC condition found as the dominant in almost all cases. NPS pollutant loads among different LULC changes also increased with changes in LULC condition from 1984 to 2013. While urbanization was found to be the dominant LULC change with the highest pollutant load in all the catchments. Results from ANOVA reveals that statistically most significant ( p changes on NPS pollution. The findings of this study may be useful to water resource planners in controlling water pollution

  4. Topics in supergravity and string theory

    International Nuclear Information System (INIS)

    Eastaugh, A.G.

    1987-01-01

    The first topic covered in this dissertation concerns the harmonic expansion technique and its application to the dimensional compactification of higher dimensional supergravity. A simple example is given to explain the method and then the method is applied to the problem of obtaining the mass spectrum of the squashed seven-sphere compactification of eleven dimensional supergravity. The second topic concerns the application of Fujikawa's method of anomaly calculation to the calculation of the critical dimension of various string models. The third topic is a study and explicit calculation of the Fock space representation of the vertex in Witten's formulation of the interacting open bosonic string field theory

  5. Topical report review status

    International Nuclear Information System (INIS)

    1982-08-01

    A Topical Report Review Status is scheduled to be published semi-annually. The primary purpose of this document is to provide periodic progress reports of on-going topical report reviews, to identify those topical reports for which the Nuclear Regulatory Commission (NRC) staff review has been completed and, to the extent practicable, to provide NRC management with sufficient information regarding the conduct of the topical report program to permit taking whatever actions deemed necessary or appropriate. This document is also intended to be a source of information to NRC Licensing Project Managers and other NRC personnel regarding the status of topical reports which may be referenced in applications for which they have responsibility. This status report is published primarily for internal NRC use in managing the topical report program, but is also used by NRC to advise the industry of report review status

  6. Topical report review status

    International Nuclear Information System (INIS)

    1983-01-01

    A Topical Report Review Status is scheduled to be published semi-annually. The primary purpose of this document is to provide periodic progress reports of on-going topical report reviews, to identify those topical reports for which the Nuclear Regulatory Commission (NRC) staff review has been completed and, to the extent practicable, to provide NRC management with sufficient information regarding the conduct of the topical report program to permit taking whatever actions deemed necessary or appropriate. This document is also intended to be a source of information to NRC Licensing Project Managers and other NRC personnel regarding the status of topical reports which may be referenced in applications for which they have responsibility. This status report is published primarily for internal NRC use in managing the topical report program, but is also used by NRC to advise the industry of report review status

  7. Topic Prominence in Chinese EFL Learners' Interlanguage

    Science.gov (United States)

    Li, Shaopeng; Yang, Lianrui

    2014-01-01

    The present study aims to investigate the general characteristics of topicprominent typological interlanguage development of Chinese learners of English in terms of acquiring subject-prominent English structures from a discourse perspective. Topic structures mainly appear in Chinese discourse in the form of topic chains (Wang, 2002; 2004). The…

  8. Topics in statistical mechanics

    International Nuclear Information System (INIS)

    Elser, V.

    1984-05-01

    This thesis deals with four independent topics in statistical mechanics: (1) the dimer problem is solved exactly for a hexagonal lattice with general boundary using a known generating function from the theory of partitions. It is shown that the leading term in the entropy depends on the shape of the boundary; (2) continuum models of percolation and self-avoiding walks are introduced with the property that their series expansions are sums over linear graphs with intrinsic combinatorial weights and explicit dimension dependence; (3) a constrained SOS model is used to describe the edge of a simple cubic crystal. Low and high temperature results are derived as well as the detailed behavior near the crystal facet; (4) the microscopic model of the lambda-transition involving atomic permutation cycles is reexamined. In particular, a new derivation of the two-component field theory model of the critical behavior is presented. Results for a lattice model originally proposed by Kikuchi are extended with a high temperature series expansion and Monte Carlo simulation. 30 references

  9. Topics in supersymmetric theories

    International Nuclear Information System (INIS)

    Nemeschansky, D.D.

    1984-01-01

    This thesis discusses four different topics in supersymmetric theories. In the first part models in which supersymmetry is broken by the Fayet-Iliopoulos mechanism are considered. The possibility that scalar quark and lepton masses might arise radiatively in such theories is explored. In the second part supersymmetric grand unified models with a sliding singlet are considered. The author reviews the argument that the sliding singlet does not work in models with large supersymmetry breaking. Then he considers the possibility of using a sliding singlet with low energy supersymmetry breaking. The third part of the thesis deals with the entropy problem of supersymmetric theories. Most supersymmetric models possess a decoupled particle with mass of order 100 GeV which is copiously produced in the early universe and whose decay produces huge amounts of entropy. The author shows how this problem can be avoided in theories in which the hidden sector contains several light fields. In the fourth part effective Lagrangians for supersymmetric theories are studied. The anomalous pion interaction for supersymmetric theories is written down. General properties of this term are studied both on compact and non-compact manifolds

  10. Long-Term Hydrologic Impact Assessment of Non-point Source Pollution Measured Through Land Use/Land Cover (LULC) Changes in a Tropical Complex Catchment

    Science.gov (United States)

    Abdulkareem, Jabir Haruna; Sulaiman, Wan Nor Azmin; Pradhan, Biswajeet; Jamil, Nor Rohaizah

    2018-03-01

    The contribution of non-point source pollution (NPS) to the contamination of surface water is an issue of growing concern. Non-point source (NPS) pollutants are of various types and altered by several site-specific factors making them difficult to control due to complex uncertainties involve in their behavior. Kelantan River basin, Malaysia is a tropical catchment receiving heavy monsoon rainfall coupled with intense land use/land cover (LULC) changes making the area consistently flood prone thereby deteriorating the surface water quality in the area. This study was conducted to determine the spatio-temporal variation of NPS pollutant loads among different LULC changes and to establish a NPS pollutant loads relationships among LULC conditions and sub-basins in each catchment. Four pollutants parameters such as total suspended solids (TSS), total phosphorus (TP), total nitrogen (TN) and ammonia nitrogen (AN) were chosen with their corresponding event mean concentration values (EMC). Soil map and LULC change maps corresponding to 1984, 2002 and 2013 were used for the calculation of runoff and NPS pollutant loads using numeric integration in a GIS environment. Analysis of Variance (ANOVA) was conducted for the comparison of NPS pollutant loads among the three LULC conditions used and the sub-basins in each catchment. The results showed that the spatio-temporal variation of pollutant loads in almost all the catchments increased with changes in LULC condition as one moves from 1984 to 2013, with 2013 LULC condition found as the dominant in almost all cases. NPS pollutant loads among different LULC changes also increased with changes in LULC condition from 1984 to 2013. While urbanization was found to be the dominant LULC change with the highest pollutant load in all the catchments. Results from ANOVA reveals that statistically most significant (p < 0.05) pollutant loads were obtained from 2013 LULC conditions, while statistically least significant (p < 0.05) pollutant

  11. Topics in Bethe Ansatz

    Science.gov (United States)

    Wang, Chunguang

    Integrable quantum spin chains have close connections to integrable quantum field. theories, modern condensed matter physics, string and Yang-Mills theories. Bethe. ansatz is one of the most important approaches for solving quantum integrable spin. chains. At the heart of the algebraic structure of integrable quantum spin chains is. the quantum Yang-Baxter equation and the boundary Yang-Baxter equation. This. thesis focuses on four topics in Bethe ansatz. The Bethe equations for the isotropic periodic spin-1/2 Heisenberg chain with N. sites have solutions containing ±i/2 that are singular: both the corresponding energy and the algebraic Bethe ansatz vector are divergent. Such solutions must be carefully regularized. We consider a regularization involving a parameter that can be. determined using a generalization of the Bethe equations. These generalized Bethe. equations provide a practical way of determining which singular solutions correspond. to eigenvectors of the model. The Bethe equations for the periodic XXX and XXZ spin chains admit singular. solutions, for which the corresponding eigenvalues and eigenvectors are ill-defined. We use a twist regularization to derive conditions for such singular solutions to bephysical, in which case they correspond to genuine eigenvalues and eigenvectors of. the Hamiltonian. We analyze the ground state of the open spin-1/2 isotropic quantum spin chain. with a non-diagonal boundary term using a recently proposed Bethe ansatz solution. As the coefficient of the non-diagonal boundary term tends to zero, the Bethe roots. split evenly into two sets: those that remain finite, and those that become infinite. We. argue that the former satisfy conventional Bethe equations, while the latter satisfy a. generalization of the Richardson-Gaudin equations. We derive an expression for the. leading correction to the boundary energy in terms of the boundary parameters. We argue that the Hamiltonians for A(2) 2n open quantum spin chains

  12. PREFACE: CEWQO Topical Issue CEWQO Topical Issue

    Science.gov (United States)

    Bozic, Mirjana; Man'ko, Margarita

    2009-09-01

    Sascha Wallentowitz), 2004 (Trieste, Italy, by Naseem Rahman and Sascha Wallentowitz), 2005 (Bilkent, Ankara, by Alexander Shumovsky), 2006 (Vienna, by Helmut Rauch), 2007 (Palermo, Italy, by Antonino Messina) and 2008 (Belgrade, by Mirjana Bozic). The CEWQO series developed in two directions following the rapid development of quantum optics and the transitional development of the scientific collaboration of Central European researchers with researchers from old and new emerging Central European countries, and from all over the world. The topics discussed at CEWQO 08 were divided into ten groups that aimed to cover the broad scope of modern quantum optics: Fundamental aspects of quantum optics and quantum mechanics Single photons and photon pairs Cavity and circuit QED Atoms in intense fields Neutron, atom and molecular quantum optics Quantum gases and fluids Coherence, entanglement and decoherence Optical properties of condensed matter and nanostructures Open quantum systems and chaos Quantum information processing Central European Workshops on Quantum Optics realize and are consistent with a wider idea, and a social, economical, cultural and political program promoted since 1989 by the Central European Initiative (CEI), the main goal of which was to help transition countries in Central Europe to become closer to the EU. The resulting support of the CEI, first obtained thanks to the scientific reputation, organizing activities, and efforts of Helmut Rauch, has been very important for the organization of the CEWQO in recent years, particularly in 2008. The support of the Sixth and Seventh Framework Programs of the European Commission was also very important. A short review of papers in this topical issue A principal role in this topical issue is played by the photon. Vuletic et al describe the mapping of the photon-polarization state onto a single collective-spin excitation (magnon) shared between two atomic ensembles. A heralded quantum memory based on this mapping is

  13. Topical Session on Materials Management

    International Nuclear Information System (INIS)

    2002-01-01

    At its second meeting, in Paris, 5-7 December 2001, the WPDD held two topical sessions on the D and D Safety Case and on the Management of Materials from D and D, respectively. This report documents the topical session on the management of materials. Presentations during the topical session covered key aspects of the management of materials and meant to provide an exchange of information and experience, including: Experience and lessons learnt from VLLW and non-radioactive material management in Spain and Germany with special attention to recycling (How specific solutions came about? Are there 'generic' examples for wider adoption?); Risk assessment of recycling and non-recycling: a CPD study; Waste acceptance issues within different national contexts (What constraints are there on the waste receiving body and what flexibility can the latter have? What constraints does this impose on D and D implementers? What about wastes are without current solution? What needs to be done? What about large items and 'difficult' waste in general?); Radiological characterisation of materials during decommissioning, particularly difficult situations - large volumes, large items,.. wastes, heterogeneous streams (What examples of established practice? What are the approaches or aspects that set the regulatory requirements? How can the flow rates be large but the answers acceptable? How much is needed to be known for later action, e. g., disposal, release, protection of worker, etc.); Radiological characterisation of buildings as they stand, in order to allow conventional demolition (What are strategies for optimisation of characterisation? How much needs to be known to take action later? e.g. for storage, disposal, release, cost estimation and ALARA? What needs to be done in advance and after decommissioning/dismantling?). At the end of each presentation time was allotted for discussion of the paper. Integral to the Topical Session was a facilitated plenary discussion on the topical

  14. Influence of input matrix representation on topic modelling performance

    CSIR Research Space (South Africa)

    De Waal, A

    2010-11-01

    Full Text Available Topic models explain a collection of documents with a small set of distributions over terms. These distributions over terms define the topics. Topic models ignore the structure of documents and use a bag-of-words approach which relies solely...

  15. Land Cover - Minnesota Land Cover Classification System

    Data.gov (United States)

    Minnesota Department of Natural Resources — Land cover data set based on the Minnesota Land Cover Classification System (MLCCS) coding scheme. This data was produced using a combination of aerial photograph...

  16. Alternative cover design

    International Nuclear Information System (INIS)

    1988-11-01

    The special study on Alternative Cover Designs is one of several studies initiated by the US Department of Energy (DOE) in response to the proposed US Environmental Protection Agency (EPA) groundwater standards. The objective of this study is to investigate the possibility of minimizing the infiltration of precipitation through stabilized tailings piles by altering the standard design of covers currently used on the Uranium Mill Tailings Remedial Action (UMTRA) Project. Prior. to the issuance of the proposed standards, UMTRA Project piles had common design elements to meet the required criteria, the most important of which were for radon diffusion, long-term stability, erosion protection, and groundwater protection. The standard pile covers consisted of three distinct layers. From top to bottom they were: rock for erosion protection; a sand bedding layer; and the radon barrier, usually consisting of a clayey sand material, which also functioned to limit infiltration into the tailings. The piles generally had topslopes from 2 to 4 percent and sideslopes of 20 percent

  17. Selected topics from classical bacterial genetics.

    Science.gov (United States)

    Raleigh, Elisabeth A; Elbing, Karen; Brent, Roger

    2002-08-01

    Current cloning technology exploits many facts learned from classical bacterial genetics. This unit covers those that are critical to understanding the techniques described in this book. Topics include antibiotics, the LAC operon, the F factor, nonsense suppressors, genetic markers, genotype and phenotype, DNA restriction, modification and methylation and recombination.

  18. Lecture Notes on Topics in Accelerator Physics

    Energy Technology Data Exchange (ETDEWEB)

    Chao, Alex W.

    2002-11-15

    These are lecture notes that cover a selection of topics, some of them under current research, in accelerator physics. I try to derive the results from first principles, although the students are assumed to have an introductory knowledge of the basics. The topics covered are: (1) Panofsky-Wenzel and Planar Wake Theorems; (2) Echo Effect; (3) Crystalline Beam; (4) Fast Ion Instability; (5) Lawson-Woodward Theorem and Laser Acceleration in Free Space; (6) Spin Dynamics and Siberian Snakes; (7) Symplectic Approximation of Maps; (8) Truncated Power Series Algebra; and (9) Lie Algebra Technique for nonlinear Dynamics. The purpose of these lectures is not to elaborate, but to prepare the students so that they can do their own research. Each topic can be read independently of the others.

  19. Lecture Notes on Topics in Accelerator Physics

    International Nuclear Information System (INIS)

    Chao, Alex W.

    2002-01-01

    These are lecture notes that cover a selection of topics, some of them under current research, in accelerator physics. I try to derive the results from first principles, although the students are assumed to have an introductory knowledge of the basics. The topics covered are: (1) Panofsky-Wenzel and Planar Wake Theorems; (2) Echo Effect; (3) Crystalline Beam; (4) Fast Ion Instability; (5) Lawson-Woodward Theorem and Laser Acceleration in Free Space; (6) Spin Dynamics and Siberian Snakes; (7) Symplectic Approximation of Maps; (8) Truncated Power Series Algebra; and (9) Lie Algebra Technique for nonlinear Dynamics. The purpose of these lectures is not to elaborate, but to prepare the students so that they can do their own research. Each topic can be read independently of the others

  20. Diclofenac Topical (osteoarthritis pain)

    Science.gov (United States)

    ... gel (Voltaren) is used to relieve pain from osteoarthritis (arthritis caused by a breakdown of the lining ... Diclofenac topical liquid (Pennsaid) is used to relieve osteoarthritis pain in the knees. Diclofenac is in a ...

  1. Diclofenac Topical (actinic keratosis)

    Science.gov (United States)

    ... topical gel (Solaraze) is used to treat actinic keratosis (flat, scaly growths on the skin caused by ... The way diclofenac gel works to treat actinic keratosis is not known.Diclofenac is also available as ...

  2. Topics in Nuclear Astrophysics

    International Nuclear Information System (INIS)

    Chung, K.C.

    1982-01-01

    Some topics in nuclear astrophysics are discussed, e.g.: highly evolved stellar cores, stellar evolution (through the temperature analysis of stellar surface), nucleosynthesis and finally the solar neutrino problem. (L.C.) [pt

  3. SETI: A good introductory physics topic

    Science.gov (United States)

    Hobson, Art

    1997-04-01

    If America is to achieve the science literacy that is essential to industrialized democracy, all students must study such topics as scientific methodology, pseudoscience, ozone depletion, and global warming. My large-enrollment liberal-arts physics course covers the great principles of physics along with several such philosophical and societal topics. It is easy to include the interdisciplinary context of physics in courses for non-scientists, because these courses are flexible, conceptual, and taught to students whose interests span a broad range. Students find these topics relevant and fascinating, leading to large enrollments by non-scientists even in courses labeled ''physics.'' I will discuss my approach to teaching the search for extra-terrestrial intelligence (SETI), a topic with lots of good physics and with connections to scientific methodology and pseudoscience. A textbook for this kind of course has been published, Physics: Concepts and Connections (Prentice-Hall, 1995).

  4. 77 FR 48733 - Transitional Program for Covered Business Method Patents-Definitions of Covered Business Method...

    Science.gov (United States)

    2012-08-14

    ... Office 37 CFR Part 42 Transitional Program for Covered Business Method Patents--Definitions of Covered... Business Method Patents-- Definitions of Covered Business Method Patent and Technological Invention AGENCY... forth in detail the definitions of the terms ``covered business method patent'' and ``technological...

  5. Topical Drugs for Pain Relief

    Directory of Open Access Journals (Sweden)

    Anjali Srinivasan

    2015-03-01

    Full Text Available Topical therapy helps patients with oral and perioral pain problems such as ulcers, burning mouth syndrome, temporomandibular disorders, neuromas, neuropathies and neuralgias. Topical drugs used in the field of dentistry are topical anaesthetics, topical analgesics, topical antibiotics and topical corticosteroids. It provides symptomatic/curative effect. Topical drugs are easy to apply, avoids hepatic first pass metabolism and more sites specific. But it can only be used for medications that require low plasma concentrations to achieve a therapeutic effect.

  6. Discriminative Relational Topic Models.

    Science.gov (United States)

    Chen, Ning; Zhu, Jun; Xia, Fei; Zhang, Bo

    2015-05-01

    Relational topic models (RTMs) provide a probabilistic generative process to describe both the link structure and document contents for document networks, and they have shown promise on predicting network structures and discovering latent topic representations. However, existing RTMs have limitations in both the restricted model expressiveness and incapability of dealing with imbalanced network data. To expand the scope and improve the inference accuracy of RTMs, this paper presents three extensions: 1) unlike the common link likelihood with a diagonal weight matrix that allows the-same-topic interactions only, we generalize it to use a full weight matrix that captures all pairwise topic interactions and is applicable to asymmetric networks; 2) instead of doing standard Bayesian inference, we perform regularized Bayesian inference (RegBayes) with a regularization parameter to deal with the imbalanced link structure issue in real networks and improve the discriminative ability of learned latent representations; and 3) instead of doing variational approximation with strict mean-field assumptions, we present collapsed Gibbs sampling algorithms for the generalized relational topic models by exploring data augmentation without making restricting assumptions. Under the generic RegBayes framework, we carefully investigate two popular discriminative loss functions, namely, the logistic log-loss and the max-margin hinge loss. Experimental results on several real network datasets demonstrate the significance of these extensions on improving prediction performance.

  7. Satellite DNA: An Evolving Topic.

    Science.gov (United States)

    Garrido-Ramos, Manuel A

    2017-09-18

    Satellite DNA represents one of the most fascinating parts of the repetitive fraction of the eukaryotic genome. Since the discovery of highly repetitive tandem DNA in the 1960s, a lot of literature has extensively covered various topics related to the structure, organization, function, and evolution of such sequences. Today, with the advent of genomic tools, the study of satellite DNA has regained a great interest. Thus, Next-Generation Sequencing (NGS), together with high-throughput in silico analysis of the information contained in NGS reads, has revolutionized the analysis of the repetitive fraction of the eukaryotic genomes. The whole of the historical and current approaches to the topic gives us a broad view of the function and evolution of satellite DNA and its role in chromosomal evolution. Currently, we have extensive information on the molecular, chromosomal, biological, and population factors that affect the evolutionary fate of satellite DNA, knowledge that gives rise to a series of hypotheses that get on well with each other about the origin, spreading, and evolution of satellite DNA. In this paper, I review these hypotheses from a methodological, conceptual, and historical perspective and frame them in the context of chromosomal organization and evolution.

  8. Topical botulinum toxin.

    Science.gov (United States)

    Collins, Ashley; Nasir, Adnan

    2010-03-01

    Nanotechnology is a rapidly growing discipline that capitalizes on the unique properties of matter engineered on the nanoscale. Vehicles incorporating nanotechnology have led to great strides in drug delivery, allowing for increased active ingredient stability, bioavailability, and site-specific targeting. Botulinum toxin has historically been used for the correction of neurological and neuromuscular disorders, such as torticollis, blepharospasm, and strabismus. Recent dermatological indications have been for the management of axillary hyperhydrosis and facial rhytides. Traditional methods of botulinum toxin delivery have been needle-based. These have been associated with increased pain and cost. Newer methods of botulinum toxin formulation have yielded topical preparations that are bioactive in small pilot clinical studies. While there are some risks associated with topical delivery, the refinement and standardization of delivery systems and techniques for the topical administration of botulinum toxin using nanotechnology is anticipated in the near future.

  9. Topics in current aerosol research (part2)

    CERN Document Server

    Hidy, G M

    1972-01-01

    Topics in Current Aerosol Research, Part 2 contains some selected articles in the field of aerosol study. The chosen topics deal extensively with the theory of diffusiophoresis and thermophoresis. Also covered in the book is the mathematical treatment of integrodifferential equations originating from the theory of aerosol coagulation. The book is the third volume of the series entitled International Reviews in Aerosol Physics and Chemistry. The text offers significant understanding of the methods employed to develop a theory for thermophoretic and diffusiophoretic forces acting on spheres in t

  10. Conference on Stochastic Analysis and Related Topics

    CERN Document Server

    Peterson, Jonathon

    2017-01-01

    The articles in this collection are a sampling of some of the research presented during the conference “Stochastic Analysis and Related Topics”, held in May of 2015 at Purdue University in honor of the 60th birthday of Rodrigo Bañuelos. A wide variety of topics in probability theory is covered in these proceedings, including heat kernel estimates, Malliavin calculus, rough paths differential equations, Lévy processes, Brownian motion on manifolds, and spin glasses, among other topics.

  11. Applied atomic and collision physics special topics

    CERN Document Server

    Massey, H S W; Bederson, Benjamin

    1982-01-01

    Applied Atomic Collision Physics, Volume 5: Special Topics deals with topics on applications of atomic collisions that were not covered in the first four volumes of the treatise. The book opens with a chapter on ultrasensitive chemical detectors. This is followed by separate chapters on lighting, magnetohydrodynamic electrical power generation, gas breakdown and high voltage insulating gases, thermionic energy converters, and charged particle detectors. Subsequent chapters deal with the operation of multiwire drift and proportional chambers and streamer chambers and their use in high energy p

  12. Evaluation of the short- and long-term effectiveness and safety of fully covered self-expandable metal stents for drainage of pancreatic fluid collections: results of a Spanish nationwide registry.

    Science.gov (United States)

    Vazquez-Sequeiros, Enrique; Baron, Todd H; Pérez-Miranda, Manuel; Sánchez-Yagüe, Andres; Gornals, Joan; Gonzalez-Huix, Ferran; de la Serna, Carlos; Gonzalez Martin, Juan Angel; Gimeno-Garcia, Antonio Z; Marra-Lopez, Carlos; Castellot, Ana; Alberca, Fernando; Fernandez-Urien, Ignacio; Aparicio, Jose Ramon; Legaz, Maria Luisa; Sendino, Oriol; Loras, Carmen; Subtil, Jose Carlos; Nerin, Juan; Perez-Carreras, Mercedes; Diaz-Tasende, Jose; Perez, Gustavo; Repiso, Alejandro; Vilella, Angels; Dolz, Carlos; Alvarez, Alberto; Rodriguez, Santiago; Esteban, Jose Miguel; Juzgado, Diego; Albillos, Agustin

    2016-09-01

    Initial reports suggest that fully covered self-expandable metal stents (FCSEMSs) may be better suited for drainage of dense pancreatic fluid collections (PFCs), such as walled-off pancreatic necrosis. The primary aim was to analyze the effectiveness and safety of FCSEMSs for drainage of different types of PFCs in a large cohort. The secondary aim was to investigate which type of FCSEMS is superior. This was a retrospective, noncomparative review of a nationwide database involving all hospitals in Spain performing EUS-guided PFC drainage. From April 2008 to August 2013, all patients undergoing PFC drainage with an FCSEMS were included in a database. The main outcome measurements were technical success, short-term (2 weeks) and long-term (6 months) effectiveness, adverse events, and need for surgery. The study included 211 patients (pseudocyst/walled-off pancreatic necrosis, 53%/47%). The FCSEMSs used were straight biliary (66%) or lumen-apposing (34%). Technical success was achieved in 97% of patients (95% confidence interval [CI], 93%-99%). Short-term- and long-term clinical success was obtained in 94% (95% CI, 89%-97%) and 85% (95% CI, 79%-89%) of patients, respectively. Adverse events occurred in 21% of patients (95% CI, 16%-27%): infection (11%), bleeding (7%), and stent migration and/or perforation (3%). By multivariate analysis, patient age (>58 years) and previous failed drainage were the most important factors associated with negative outcome. An FCSEMS is effective and safe for PFC drainage. Older patients with a history of unsuccessful drainage are more likely to fail EUS-guided drainage. The type of FCSEMS does not seem to influence patient outcome. Copyright © 2016 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

  13. Treatment Duration of Topics in Senior Secondary School Core ...

    African Journals Online (AJOL)

    kofimereku

    years to better equip the students for university education (Daily Graphic of. September 15th 1998). .... five items similar to those in the SS Mathematics Book 3, and covered all the sub-topics of the topic ..... Soviet Union. United States. 181. 188.

  14. Topical Treatment of Degenerative Knee Osteoarthritis.

    Science.gov (United States)

    Meng, Zengdong; Huang, Rongzhong

    2018-01-01

    This article reviews topical management strategies for degenerative osteoarthritis (OA) of the knee. A search of Pubmed, Embase and the Cochrane library using MeSH terms including "topical," "treatment," "knee" and "osteoarthritis" was carried out. Original research and review articles on the effectiveness and safety, recommendations from international published guidelines and acceptability studies of topical preparations were included. Current topical treatments included for the management of knee OA include topical nonsteroidal anti-inflammatory drugs, capsaicin, salicylates and physical treatments such as hot or cold therapy. Current treatment guidelines recommend topical nonsteroidal anti-inflammatory drugs as an alternative and even first-line therapy for OA management, especially among elderly patients. Guidelines on other topical treatments vary, from recommendations against their use, to in favor as alternative or simultaneous therapy, especially for patients with contraindications to other analgesics. Although often well-tolerated and preferred by many patients, clinical care still lags in the adoption of topical treatments. Aspects of efficacy, safety and patient quality of life data require further research. Copyright © 2018 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

  15. Health Topic XML File Description

    Science.gov (United States)

    ... this page: https://medlineplus.gov/xmldescription.html Health Topic XML File Description: MedlinePlus To use the sharing ... information categories assigned. Example of a Full Health Topic Record A record for a MedlinePlus health topic ...

  16. Topical Research: Africa.

    Science.gov (United States)

    Lynn, Karen

    This lesson plan can be used in social studies, language arts, or library research. The instructional objective is for students to select a topic of study relating to Africa, write a thesis statement, collect information from media sources, and develop a conclusion. The teacher may assign the lesson for written or oral evaluation. The teacher…

  17. Topics in quantum theory

    International Nuclear Information System (INIS)

    Yuille, A.L.

    1980-11-01

    Topics in the Yang-Mills theories of strong interactions and the quantum theories of gravity are examined, using the path integral approach, including; Yang-Mills instantons in curved spacetimes, Israel-Wilson metrics, Kaehler spacetimes, instantons and anti-instantons. (U.K.)

  18. Salicylic Acid Topical

    Science.gov (United States)

    ... the package label for more information.Apply a small amount of the salicylic acid product to one or two small areas you want to treat for 3 days ... know that children and teenagers who have chicken pox or the flu should not use topical salicylic ...

  19. Characters and Topical Diversity

    DEFF Research Database (Denmark)

    Eriksson, Rune

    2014-01-01

    The purpose of this article is to contribute to our understanding of the difference between the bestseller and the non-bestseller in nonfiction. It is noticed that many bestsellers in nonfiction belongs to the sub-genre of creative nonfiction, but also that the topics in this kind of literature i...

  20. Selected topics in magnetism

    CERN Document Server

    Gupta, L C

    1993-01-01

    Part of the ""Frontiers in Solid State Sciences"" series, this volume presents essays on such topics as spin fluctuations in Heisenberg magnets, quenching of spin fluctuations by high magnetic fields, and kondo effect and heavy fermions in rare earths amongst others.

  1. Nuclear safety - Topical issues

    International Nuclear Information System (INIS)

    1995-01-01

    The following topical issues related to nuclear safety are discussed: steam generators; maintenance strategies; control rod drive nozzle cracks; core shrouds cracks; sump strainer blockage; fire protection; computer software important for safety; safety during shutdown; operational safety experience; external hazards and other site related issues. 5 figs, 5 tabs

  2. Topical immunomodulators in dermatology

    Directory of Open Access Journals (Sweden)

    Khandpur Sujay

    2004-04-01

    Full Text Available Topical immunomodulators are agents that regulate the local immune response of the skin. They are now emerging as the therapy of choice for several immune-mediated dermatoses such as atopic dermatitis, contact allergic dermatitis, alopecia areata, psoriasis, vitiligo, connective tissue disorders such as morphea and lupus erythematosus, disorders of keratinization and several benign and malignant skin tumours, because of their comparable efficacy, ease of application and greater safety than their systemic counterparts. They can be used on a domiciliary basis for longer periods without aggressive monitoring. In this article, we have discussed the mechanism of action, common indications and side-effects of the commonly used topical immunomodulators, excluding topical steroids. Moreover, newer agents, which are still in the experimental stages, have also been described. A MEDLINE search was undertaken using the key words "topical immunomodulators, dermatology" and related articles were also searched. In addition, a manual search for many Indian articles, which are not indexed, was also carried out. Wherever possible, the full article was reviewed. If the full article could not be traced, the abstract was used.

  3. Differential Topic Models.

    Science.gov (United States)

    Chen, Changyou; Buntine, Wray; Ding, Nan; Xie, Lexing; Du, Lan

    2015-02-01

    In applications we may want to compare different document collections: they could have shared content but also different and unique aspects in particular collections. This task has been called comparative text mining or cross-collection modeling. We present a differential topic model for this application that models both topic differences and similarities. For this we use hierarchical Bayesian nonparametric models. Moreover, we found it was important to properly model power-law phenomena in topic-word distributions and thus we used the full Pitman-Yor process rather than just a Dirichlet process. Furthermore, we propose the transformed Pitman-Yor process (TPYP) to incorporate prior knowledge such as vocabulary variations in different collections into the model. To deal with the non-conjugate issue between model prior and likelihood in the TPYP, we thus propose an efficient sampling algorithm using a data augmentation technique based on the multinomial theorem. Experimental results show the model discovers interesting aspects of different collections. We also show the proposed MCMC based algorithm achieves a dramatically reduced test perplexity compared to some existing topic models. Finally, we show our model outperforms the state-of-the-art for document classification/ideology prediction on a number of text collections.

  4. Topics and topic prominence in two sign languages

    NARCIS (Netherlands)

    Kimmelman, V.

    2015-01-01

    In this paper we describe topic marking in Russian Sign Language (RSL) and Sign Language of the Netherlands (NGT) and discuss whether these languages should be considered topic prominent. The formal markers of topics in RSL are sentence-initial position, a prosodic break following the topic, and

  5. 2011 annual meeting on nuclear technology. Pt. 4. Topical sessions

    International Nuclear Information System (INIS)

    Schoenfelder, Christian; Dams, Wolfgang

    2011-01-01

    Summary report on the Topical Session of the Annual Conference on Nuclear Technology held in Berlin, 17 to 19 May 2011: - Nuclear Competence in Germany and Europe. The Topical Session: - Sodium Cooled Fast Reactors -- will be covered in a report in a further issue of atw. The reports on the Topical Sessions: - CFD-Simulations for Safety Relevant Tasks; and - Final Disposal: From Scientific Basis to Application; - Characteristics of a High Reliability Organization (HRO) Considering Experience Gained from Events at Nuclear Power Stations -- have been covered in atw 7, 8/9, and 10 (2011). (orig.)

  6. Branched polynomial covering maps

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    1999-01-01

    A Weierstrass polynomial with multiple roots in certain points leads to a branched covering map. With this as the guiding example, we formally define and study the notion of a branched polynomial covering map. We shall prove that many finite covering maps are polynomial outside a discrete branch...... set. Particular studies are made of branched polynomial covering maps arising from Riemann surfaces and from knots in the 3-sphere....

  7. Land-cover change detection

    Science.gov (United States)

    Chen, Xuexia; Giri, Chandra; Vogelmann, James

    2012-01-01

    Land cover is the biophysical material on the surface of the earth. Land-cover types include grass, shrubs, trees, barren, water, and man-made features. Land cover changes continuously.  The rate of change can be either dramatic and abrupt, such as the changes caused by logging, hurricanes and fire, or subtle and gradual, such as regeneration of forests and damage caused by insects (Verbesselt et al., 2001).  Previous studies have shown that land cover has changed dramatically during the past sevearal centuries and that these changes have severely affected our ecosystems (Foody, 2010; Lambin et al., 2001). Lambin and Strahlers (1994b) summarized five types of cause for land-cover changes: (1) long-term natural changes in climate conditions, (2) geomorphological and ecological processes, (3) human-induced alterations of vegetation cover and landscapes, (4) interannual climate variability, and (5) human-induced greenhouse effect.  Tools and techniques are needed to detect, describe, and predict these changes to facilitate sustainable management of natural resources.

  8. Relativity theory - topical

    International Nuclear Information System (INIS)

    Schmutzer, E.

    1979-01-01

    Issued on the occasion of Albert Einstein's 100th birthday the book deals topically with the special and general relativity theory. The latest experiments to confirm the relativity theory are described and the historical development of the theory is presented in detail. Emphasis is given to the disclosure of deep insights into the nature of matter. Of interest to experts in physical and natural sciences and to mathematicians

  9. Special study on vegetative covers

    International Nuclear Information System (INIS)

    1988-11-01

    This report describes the findings of a special study on the use of vegetative covers to stabilize tailings piles for the Uranium Mill Tailings Remedial Action (UMTRA) Project. The principal rationale for using plants would be to establish a dynamic system for controlling water balance. Specifically, vegetation would be used to intercept and transpire precipitation to the atmosphere, rather than allowing water to drain into the tailings and mobilize contaminants. This would facilitate compliance with groundwater standards proposed for the UMTRA Project by the Environmental Protection Agency. The goals of the study were to evaluate the feasibility of using vegetative covers on UMTRA Project piles, define the advantages and disadvantages of vegetative covers, and develop general guidelines for their use when such use seems reasonable. The principal method for the study was to analyze and apply to the UMTRA Project the results of research programs on vegetative covers at other US Department of Energy (DOE) waste management facilities. The study also relied upon observations made of existing stabilized piles at UMTRA Project sites where natural vegetation is growing on the rock-covered surfaces. Water balance and erosion models were also used to quantify the long-term performance of vegetative covers planned for the topslopes of stabilized piles at Grand Junction and Durango, Colorado, two UMTRA Project sites where the decision was made during the course of this special study to use vegetative covers. Elements in the design and construction of the vegetative covers at these two sites are discussed in the report, with explanations of the differing features that reflect differing environmental conditions. 28 refs., 18 figs., 9 tabs

  10. Topic Visualization and Survival Analysis

    OpenAIRE

    Wang, Ping Jr

    2017-01-01

    Latent semantic structure in a text collection is called a topic. In this thesis, we aim to visualize topics in the scientific literature and detect active or inactive research areas based on their lifetime. Topics were extracted from over 1 million abstracts from the arXiv.org database using Latent Dirichlet Allocation (LDA). Hellinger distance measures similarity between two topics. Topics are determined to be relevant if their pairwise distances are smaller than the threshold of Hellinger ...

  11. Branched polynomial covering maps

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    2002-01-01

    A Weierstrass polynomial with multiple roots in certain points leads to a branched covering map. With this as the guiding example, we formally define and study the notion of a branched polynomial covering map. We shall prove that many finite covering maps are polynomial outside a discrete branch ...... set. Particular studies are made of branched polynomial covering maps arising from Riemann surfaces and from knots in the 3-sphere. (C) 2001 Elsevier Science B.V. All rights reserved.......A Weierstrass polynomial with multiple roots in certain points leads to a branched covering map. With this as the guiding example, we formally define and study the notion of a branched polynomial covering map. We shall prove that many finite covering maps are polynomial outside a discrete branch...

  12. Landfill Top Covers

    DEFF Research Database (Denmark)

    Scheutz, Charlotte; Kjeldsen, Peter

    2011-01-01

    The purpose of the final cover of a landfill is to contain the waste and to provide for a physical separation between the waste and the environment for protection of public health. Most landfill covers are designed with the primary goal to reduce or prevent infiltration of precipitation...... into the landfill in order to minimize leachate generation. In addition the cover also has to control the release of gases produced in the landfill so the gas can be ventilated, collected and utilized, or oxidized in situ. The landfill cover should also minimize erosion and support vegetation. Finally the cover...... is landscaped in order to fit into the surrounding area/environment or meet specific plans for the final use of the landfill. To fulfill the above listed requirements landfill covers are often multicomponent systems which are placed directly on top of the waste. The top cover may be placed immediately after...

  13. Topics in field theory

    CERN Document Server

    Karpilovsky, G

    1989-01-01

    This monograph gives a systematic account of certain important topics pertaining to field theory, including the central ideas, basic results and fundamental methods.Avoiding excessive technical detail, the book is intended for the student who has completed the equivalent of a standard first-year graduate algebra course. Thus it is assumed that the reader is familiar with basic ring-theoretic and group-theoretic concepts. A chapter on algebraic preliminaries is included, as well as a fairly large bibliography of works which are either directly relevant to the text or offer supplementary material of interest.

  14. Topics in CP violation

    International Nuclear Information System (INIS)

    Quinn, H.R.

    1993-02-01

    Given the varied backgrounds of the members of this audience this talk will be a grab bag of topics related to the general theme of CP Violation. I do not have time to dwell in detail on any of them. First, for the astronomers and astrophysicists among you, I want to begin by reviewing the experimental status of evidence for CP violation in particle processes. There is only one system where this has been observed, and that is in the decays of neutral K mesons

  15. Topics in Nonlinear Dynamics

    DEFF Research Database (Denmark)

    Mosekilde, Erik

    Through a significant number of detailed and realistic examples this book illustrates how the insights gained over the past couple of decades in the fields of nonlinear dynamics and chaos theory can be applied in practice. Aomng the topics considered are microbiological reaction systems, ecological...... food-web systems, nephron pressure and flow regulation, pulsatile secretion of hormones, thermostatically controlled radiator systems, post-stall maneuvering of aircrafts, transfer electron devices for microwave generation, economic long waves, human decision making behavior, and pattern formation...... in chemical reaction-diffusion systems....

  16. Topics in CP violation

    Science.gov (United States)

    Quinn, H. R.

    1993-02-01

    Given the varied backgrounds of the members of this audience this talk will be a grab bag of topics related to the general theme of CP Violation. I do not have time to dwell in detail on any of them. First, for the astronomers and astrophysicists among you, I want to begin by reviewing the experimental status of evidence for CP violation in particle processes. There is only one system where this has been observed, and that is in the decays of neutral K mesons.

  17. Topics in Operator Theory

    CERN Document Server

    Ball, Joseph A; Helton, JWilliam; Rodman, Leiba; Spitkovsky, Iiya

    2010-01-01

    This is the first volume of a collection of original and review articles on recent advances and new directions in a multifaceted and interconnected area of mathematics and its applications. It encompasses many topics in theoretical developments in operator theory and its diverse applications in applied mathematics, physics, engineering, and other disciplines. The purpose is to bring in one volume many important original results of cutting edge research as well as authoritative review of recent achievements, challenges, and future directions in the area of operator theory and its applications.

  18. Covering of the electric power service

    International Nuclear Information System (INIS)

    Unidad de Planeacion Minero Energetica, UPME

    2000-01-01

    In this article it is sought to deepen more in the topic of the covering of the electric power service, especially in the related with the mechanisms that could facilitate their amplification. In the new market outline, in the one that the participation of the agents is encouraged in all the activities of the chain of services in which the state is not direct lender of the same one, it is confused the form like a covering will be achieved that is of agreement with the goals that intend in the national plan of development and in the sub sectorial plans. Although the rules of the market one comes consolidating, the process of linking of the private capital, especially in the distribution activity, it evidences the importance of to settle down and to define responsibilities and explicit mechanisms in the topic of expansion of the covering. A first interpretation of the ruled indicates the obligation of the state of extending the covering to 100% and of assuming the projects that don't undertake the matters. This would be the reading from the traditional mentality. However, the regulation of you public services of electricity don't demand a total covering, but rather it covers to the users that have the capacity to assume, with their own resources, the efficient costs of benefit. The service will also be lent to residential users that don't have payment capacity, when there are contribution resources or fiscal resources for subsidiary

  19. Conclusion from the fifth topic

    International Nuclear Information System (INIS)

    Gin, St.; Advocat, Th.

    1997-01-01

    The topic ''mechanics and alteration kinetics of glasses'' is a crucial point for the understanding of the long-term behaviour of nuclear glasses. Kinetic models used in simulation are based on the works made by Grambow who imputes the control of the alteration kinetics of borosilicate glasses to the desorption of the ortho-silica acid produced at the reactive interface. The ensuing kinetics law requires the existence of an equilibrium of the silica at the interface glass/gel and the existence of a linear concentration gradient dissolved in the interstitial gel solution. The role of the gel needs further studies to be well understood. The difficulty lies in the fact that the composition and the structure of the gel varies with time, space (anisotropy) and with the conditions of alteration (temperature, pH, flowrate...). (A.C.)

  20. Low temperatures - hot topic

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1988-09-15

    Neutrino mass measurements, next-generation double beta experiments, solar neutrino detection, searches for magnetic monopoles and the challenge of discovering what most of the Universe is made of (dark matter), not to mention axions (cosmic and solar), supersymmetric neutral particles and cosmic neutrinos. All this physics could use cryogenic techniques. Thus the second European Workshop on Low Temperature Devices for the Detection of Low Energy Neutrinos and Dark Matter, held at LAPP (Annecy) in May, covered an active and promising field.

  1. Low temperatures - hot topic

    International Nuclear Information System (INIS)

    Anon.

    1988-01-01

    Neutrino mass measurements, next-generation double beta experiments, solar neutrino detection, searches for magnetic monopoles and the challenge of discovering what most of the Universe is made of (dark matter), not to mention axions (cosmic and solar), supersymmetric neutral particles and cosmic neutrinos. All this physics could use cryogenic techniques. Thus the second European Workshop on Low Temperature Devices for the Detection of Low Energy Neutrinos and Dark Matter, held at LAPP (Annecy) in May, covered an active and promising field

  2. Topics on continua

    CERN Document Server

    Macias, Sergio

    2005-01-01

    Specialized as it might be, continuum theory is one of the most intriguing areas in mathematics. However, despite being popular journal fare, few books have thoroughly explored this interesting aspect of topology. In Topics on Continua, Sergio Macías, one of the field's leading scholars, presents four of his favorite continuum topics: inverse limits, Jones's set function T, homogenous continua, and n-fold hyperspaces, and in doing so, presents the most complete set of theorems and proofs ever contained in a single topology volume. Many of the results presented have previously appeared only in research papers, and some appear here for the first time. After building the requisite background and exploring the inverse limits of continua, the discussions focus on Professor Jones''s set function T and continua for which T is continuous. An introduction to topological groups and group actions lead to a proof of Effros''s Theorem, followed by a presentation of two decomposition theorems. The author then offers an...

  3. Common Core: Teaching Optimum Topic Exploration (TOTE)

    Science.gov (United States)

    Karge, Belinda Dunnick; Moore, Roxane Kushner

    2015-01-01

    The Common Core has become a household term and yet many educators do not understand what it means. This article explains the historical perspectives of the Common Core and gives guidance to teachers in application of Teaching Optimum Topic Exploration (TOTE) necessary for full implementation of the Common Core State Standards. An effective…

  4. Armored Geomembrane Cover Engineering

    Directory of Open Access Journals (Sweden)

    Kevin Foye

    2011-06-01

    Full Text Available Geomembranes are an important component of modern engineered barriers to prevent the infiltration of stormwater and runoff into contaminated soil and rock as well as waste containment facilities—a function generally described as a geomembrane cover. This paper presents a case history involving a novel implementation of a geomembrane cover system. Due to this novelty, the design engineers needed to assemble from disparate sources the design criteria for the engineering of the cover. This paper discusses the design methodologies assembled by the engineering team. This information will aid engineers designing similar cover systems as well as environmental and public health professionals selecting site improvements that involve infiltration barriers.

  5. Percent Forest Cover (Future)

    Data.gov (United States)

    U.S. Environmental Protection Agency — Forests provide economic and ecological value. High percentages of forest cover (FORPCTFuture) generally indicate healthier ecosystems and cleaner surface water....

  6. Percent Forest Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — Forests provide economic and ecological value. High percentages of forest cover (FORPCT) generally indicate healthier ecosystems and cleaner surface water. More...

  7. Changing the Topic. Topic Position in Ancient Greek Word Order

    NARCIS (Netherlands)

    Allan, R.J.

    2014-01-01

    Ancient Greek, topics can be expressed as intra-clausal constituents but they can also precede or follow the main clause as extra-clausal constituents. Together, these various topic expressions constitute a coherent system of complementary pragmatic functions. For a comprehensive account of topic

  8. Topics in atomic physics

    CERN Document Server

    Burkhardt, Charles E

    2006-01-01

    The study of atomic physics propelled us into the quantum age in the early twentieth century and carried us into the twenty-first century with a wealth of new and, in some cases, unexplained phenomena. Topics in Atomic Physics provides a foundation for students to begin research in modern atomic physics. It can also serve as a reference because it contains material that is not easily located in other sources. A distinguishing feature is the thorough exposition of the quantum mechanical hydrogen atom using both the traditional formulation and an alternative treatment not usually found in textbooks. The alternative treatment exploits the preeminent nature of the pure Coulomb potential and places the Lenz vector operator on an equal footing with other operators corresponding to classically conserved quantities. A number of difficult to find proofs and derivations are included as is development of operator formalism that permits facile solution of the Stark effect in hydrogen. Discussion of the classical hydrogen...

  9. Topics in mathematical biology

    CERN Document Server

    Hadeler, Karl Peter

    2017-01-01

    This book analyzes the impact of quiescent phases on biological models. Quiescence arises, for example, when moving individuals stop moving, hunting predators take a rest, infected individuals are isolated, or cells enter the quiescent compartment of the cell cycle. In the first chapter of Topics in Mathematical Biology general principles about coupled and quiescent systems are derived, including results on shrinking periodic orbits and stabilization of oscillations via quiescence. In subsequent chapters classical biological models are presented in detail and challenged by the introduction of quiescence. These models include delay equations, demographic models, age structured models, Lotka-Volterra systems, replicator systems, genetic models, game theory, Nash equilibria, evolutionary stable strategies, ecological models, epidemiological models, random walks and reaction-diffusion models. In each case we find new and interesting results such as stability of fixed points and/or periodic orbits, excitability...

  10. Topical Acne Treatments and Pregnancy

    Science.gov (United States)

    Topical Acne Treatments In every pregnancy, a woman starts out with a 3-5% chance of having a baby ... This sheet talks about whether exposure to topical acne treatments may increase the risk for birth defects ...

  11. Symbiosis: Rich, Exciting, Neglected Topic

    Science.gov (United States)

    Rowland, Jane Thomas

    1974-01-01

    Argues that the topic of symbiosis has been greatly neglected and underemphasized in general-biology textbooks. Discusses many types and examples of symbiosis, and provides an extensive bibliography of the literature related to this topic. (JR)

  12. KEY TOPICS IN SPORTS MEDICINE

    Directory of Open Access Journals (Sweden)

    Amir Ali Narvani

    2006-12-01

    Full Text Available Key Topics in Sports Medicine is a single quick reference source for sports and exercise medicine. It presents the essential information from across relevant topic areas, and includes both the core and emerging issues in this rapidly developing field. It covers: 1 Sports injuries, rehabilitation and injury prevention, 2 Exercise physiology, fitness testing and training, 3 Drugs in sport, 4 Exercise and health promotion, 5 Sport and exercise for special and clinical populations, 6 The psychology of performance and injury. PURPOSE The Key Topics format provides extensive, concise information in an accessible, easy-to-follow manner. AUDIENCE The book is targeted the students and specialists in sports medicine and rehabilitation, athletic training, physiotherapy and orthopaedic surgery. The editors are authorities in their respective fields and this handbook depends on their extensive experience and knowledge accumulated over the years. FEATURES The book contains the information for clinical guidance, rapid access to concise details and facts. It is composed of 99 topics which present the information in an order that is considered logical and progressive as in most texts. Chapter headings are: 1. Functional Anatomy, 2. Training Principles / Development of Strength and Power, 3. Biomechanical Principles, 4. Biomechanical Analysis, 5. Physiology of Training, 6. Monitoring of Training Progress, 7. Nutrition, 8. Hot and Cold Climates, 9. Altitude, 10. Sport and Travelling, 11. Principles of Sport Injury Diagnosis, 12. Principles of Sport and Soft Tissue Management, 13. Principles of Physical Therapy and Rehabilitation, 14. Principles of Sport Injury Prevention, 15. Sports Psychology, 16. Team Sports, 17. Psychological Aspects of Injury in Sport, 18. Injury Repair Process, 19. Basic Biomechanics of Tissue Injury, 20. Plain Film Radiography in Sport, 21. Nuclear Medicine, 22. Diagnostic Ultrasound, 23. MRI Scan, 24. Other Imaging, 5. Head Injury, 26. Eye

  13. Bare quantifier fronting as contrastive topicalization

    Directory of Open Access Journals (Sweden)

    Ion Giurgea

    2015-11-01

    Full Text Available I argue that indefinites (in particular bare quantifiers such as ‘something’, ‘somebody’, etc. which are neither existentially presupposed nor in the restriction of a quantifier over situations, can undergo topicalization in a number of Romance languages (Catalan, Italian, Romanian, Spanish, but only if the sentence contains “verum” focus, i.e. focus on a high degree of certainty of the sentence. I analyze these indefinites as contrastive topics, using Büring’s (1999 theory (where the term ‘S-topic’ is used for what I call ‘contrastive topic’. I propose that the topic is evaluated in relation to a scalar set including generalized quantifiers such as {lP $x P(x, lP MANYx P(x, lP MOSTx P(x, lP “xP(x} or {lP $xP(x, lP P(a, lP P(b …}, and that the contrastive topic is the weakest generalized quantifier in this set. The verum focus, which is part of the “comment” that co-occurs with the “Topic”, introduces a set of alternatives including degrees of certainty of the assertion. The speaker asserts that his claim is certainly true or highly probable, contrasting it with stronger claims for which the degree of probability is unknown. This explains the observation that in downward entailing contexts, the fronted quantified DPs are headed by ‘all’ or ‘many’, whereas ‘some’, small numbers or ‘at least n’ appear in upward entailing contexts. Unlike other cases of non-specific topics, which are property topics, these are quantifier topics: the topic part is a generalized quantifier, the comment is a property of generalized quantifiers. This explains the narrow scope of the fronted quantified DP.

  14. Topics in general topology

    CERN Document Server

    Morita, K

    1989-01-01

    Being an advanced account of certain aspects of general topology, the primary purpose of this volume is to provide the reader with an overview of recent developments.The papers cover basic fields such as metrization and extension of maps, as well as newly-developed fields like categorical topology and topological dynamics. Each chapter may be read independently of the others, with a few exceptions. It is assumed that the reader has some knowledge of set theory, algebra, analysis and basic general topology.

  15. Covered Bridge Security Manual

    Science.gov (United States)

    Brett Phares; Terry Wipf; Ryan Sievers; Travis Hosteng

    2013-01-01

    The design, construction, and use of covered timber bridges is all but a lost art in these days of pre-stressed concrete, high-performance steel, and the significant growth both in the volume and size of vehicles. Furthermore, many of the existing covered timber bridges are preserved only because of their status on the National Registry of Historic Places or the...

  16. Long-Term Outcomes of Double-Layered Polytetrafluoroethylene Membrane-Covered Self-Expandable Segmental Metallic Stents (Uventa) in Patients with Chronic Ureteral Obstructions: Is It Really Safe?

    Science.gov (United States)

    Kim, Myong; Hong, Bumsik; Park, Hyung Keun

    2016-12-01

    To evaluate the long-term clinical efficacy and safety of double-layered polytetrafluoroethylene membrane-covered self-expandable segmental metallic stents (Uventa) in patients with chronic ureteral obstruction. In a retrospective study, a total of 50 ureter units (44 patients) with chronic obstructions were included from July 2010 to May 2015. Indications for Uventa placement were primary stenting for malignant ureteral obstruction, failed conventional polymeric Double-J stent (PS), or percutaneous nephrostomy (PCN) technique, with comorbidities or fears limiting PS/PCN changes, or with irritation or pain due to PS/PCN. Patients underwent Uventa stent placement using the antegrade or retrograde approach. There were no immediate procedure-related complications, and all stents were placed in the proper sites. During the median follow-up of 30.9 (interquartile range [IQR], 8.1-49.0) months, the primary (no obstruction and no additional intervention) and overall success (no obstruction and no additional intervention except supplementary Uventa) was 30.0% and 34.0%, respectively. Moreover, 14 of 50 ureter units (28.0%) experienced major complications (≥Clavien-Dindo class IIIb), such as ureteroarterial fistula (three cases, 6.0%), ureteroenteric fistula (three, 6.0%), ureterovaginal fistula (one, 2.0%), ureter perforation (one, 2.0%), uncontrollable bleeding (one, 2.0%), and complete obstruction (five, 10.0%). On univariate analysis, major complications were associated with female (odds ratio [OR] = 6.000), cervical cancer (OR = 4.667), ureteral stricture length (≥6.0 cm, OR = 4.583), and placement duration (≥24.0 months, OR = 20.429; all p stent demonstrated poor treatment outcomes with frequent major complications in patients with chronic ureteral obstructions.

  17. Spatio-temporal patterns of the effects of precipitation variability and land use/cover changes on long-term changes in sediment yield in the Loess Plateau, China

    Science.gov (United States)

    Gao, Guangyao; Zhang, Jianjun; Liu, Yu; Ning, Zheng; Fu, Bojie; Sivapalan, Murugesu

    2017-09-01

    Within China's Loess Plateau there have been concerted revegetation efforts and engineering measures since the 1950s aimed at reducing soil erosion and land degradation. As a result, annual streamflow, sediment yield, and sediment concentration have all decreased considerably. Human-induced land use/cover change (LUCC) was the dominant factor, contributing over 70 % of the sediment load reduction, whereas the contribution of precipitation was less than 30 %. In this study, we use 50-year time series data (1961-2011), showing decreasing trends in the annual sediment loads of 15 catchments, to generate spatio-temporal patterns in the effects of LUCC and precipitation variability on sediment yield. The space-time variability of sediment yield was expressed notionally as a product of two factors representing (i) the effect of precipitation and (ii) the fraction of treated land surface area. Under minimal LUCC, the square root of annual sediment yield varied linearly with precipitation, with the precipitation-sediment load relationship showing coherent spatial patterns amongst the catchments. As the LUCC increased and took effect, the changes in sediment yield pattern depended more on engineering measures and vegetation restoration campaign, and the within-year rainfall patterns (especially storm events) also played an important role. The effect of LUCC is expressed in terms of a sediment coefficient, i.e., the ratio of annual sediment yield to annual precipitation. Sediment coefficients showed a steady decrease over the study period, following a linear decreasing function of the fraction of treated land surface area. In this way, the study has brought out the separate roles of precipitation variability and LUCC in controlling spatio-temporal patterns of sediment yield at catchment scale.

  18. Spatio-temporal patterns of the effects of precipitation variability and land use/cover changes on long-term changes in sediment yield in the Loess Plateau, China

    Directory of Open Access Journals (Sweden)

    G. Gao

    2017-09-01

    Full Text Available Within China's Loess Plateau there have been concerted revegetation efforts and engineering measures since the 1950s aimed at reducing soil erosion and land degradation. As a result, annual streamflow, sediment yield, and sediment concentration have all decreased considerably. Human-induced land use/cover change (LUCC was the dominant factor, contributing over 70 % of the sediment load reduction, whereas the contribution of precipitation was less than 30 %. In this study, we use 50-year time series data (1961–2011, showing decreasing trends in the annual sediment loads of 15 catchments, to generate spatio-temporal patterns in the effects of LUCC and precipitation variability on sediment yield. The space–time variability of sediment yield was expressed notionally as a product of two factors representing (i the effect of precipitation and (ii the fraction of treated land surface area. Under minimal LUCC, the square root of annual sediment yield varied linearly with precipitation, with the precipitation–sediment load relationship showing coherent spatial patterns amongst the catchments. As the LUCC increased and took effect, the changes in sediment yield pattern depended more on engineering measures and vegetation restoration campaign, and the within-year rainfall patterns (especially storm events also played an important role. The effect of LUCC is expressed in terms of a sediment coefficient, i.e., the ratio of annual sediment yield to annual precipitation. Sediment coefficients showed a steady decrease over the study period, following a linear decreasing function of the fraction of treated land surface area. In this way, the study has brought out the separate roles of precipitation variability and LUCC in controlling spatio-temporal patterns of sediment yield at catchment scale.

  19. 39 CFR 233.3 - Mail covers.

    Science.gov (United States)

    2010-07-01

    .... For purpose of these regulations, the following terms are hereby defined. (1) Mail cover is the... criminal law. (3) When time is of the essence, the Chief Postal Inspector, or designee, may act upon an... furnish information as defined in § 233.3(c)(1) to any person, except as authorized by a mail cover order...

  20. ISLSCP II Potential Natural Vegetation Cover

    Data.gov (United States)

    National Aeronautics and Space Administration — ABSTRACT: This data set was developed to describe the state of the global land cover in terms of 15 major vegetation types, plus water, before alteration by humans....

  1. Covering folded shapes

    Directory of Open Access Journals (Sweden)

    Oswin Aichholzer

    2014-05-01

    Full Text Available Can folding a piece of paper flat make it larger? We explore whether a shape S must be scaled to cover a flat-folded copy of itself. We consider both single folds and arbitrary folds (continuous piecewise isometries \\(S\\to\\mathbb{R}^2\\. The underlying problem is motivated by computational origami, and is related to other covering and fixturing problems, such as Lebesgue's universal cover problem and force closure grasps. In addition to considering special shapes (squares, equilateral triangles, polygons and disks, we give upper and lower bounds on scale factors for single folds of convex objects and arbitrary folds of simply connected objects.

  2. Addition of topical pimecrolimus to once-daily mid-potent steroid confers no short-term therapeutic benefit in the treatment of severe atopic dermatitis; a randomized controlled trial.

    Science.gov (United States)

    Spergel, J M; Boguniewicz, M; Paller, A S; Hebert, A A; Gallagher, P R; McCormick, C; Parneix-Spake, A; Hultsch, T

    2007-08-01

    Combination therapy with pimecrolimus cream 1%, a topical calcineurin inhibitor (TCI), and fluticasone propionate cream 0.05% (FP), a mid-potency topical corticosteroid, may have a synergistic effect for treatment of atopic dermatitis (AD) because their mechanism of action differs. To assess the efficacy of concomitant pimecrolimus twice daily/FP once daily vs. vehicle twice daily/FP once daily in patients with severe AD. An exploratory, 2-week, double-blind, randomized, within-patient study was conducted (n = 45). Two target areas of similar severity, size and location were assessed. Assessments included the modified Eczema Area and Severity Index (0-12 scale) (primary variable), localized investigator global assessment (0-4 scale) and Patients' Self-Assessment of Disease Severity (0-4 scale). Data for all variables were similar for the TCI/FP and vehicle/FP treatments. The efficacy observed for treatment of severe AD flares with this TCI/FP combination regimen was equivalent to that of vehicle/FP.

  3. Superconcentration and related topics

    CERN Document Server

    Chatterjee, Sourav

    2014-01-01

    A certain curious feature of random objects, introduced by the author as “super concentration,” and two related topics, “chaos” and “multiple valleys,” are highlighted in this book. Although super concentration has established itself as a recognized feature in a number of areas of probability theory in the last twenty years (under a variety of names), the author was the first to discover and explore its connections with chaos and multiple valleys. He achieves a substantial degree of simplification and clarity in the presentation of these findings by using the spectral approach. Understanding the fluctuations of random objects is one of the major goals of probability theory and a whole subfield of probability and analysis, called concentration of measure, is devoted to understanding these fluctuations. This subfield offers a range of tools for computing upper bounds on the orders of fluctuations of very complicated random variables. Usually, concentration of measure is useful when more direct prob...

  4. Topics in broken supersymmetry

    International Nuclear Information System (INIS)

    Lee, I.H.

    1984-01-01

    Studies on two topics in the framework of broken supersymmetry are presented. Chapter I is a brief introduction in which the motivation and the background of this work are discussed. In Chapter II, the author studies the decay K + → π + γγ in models with spontaneous supersymmetry breaking and find that it is generally suppressed relative to the decay K + → π + anti nu nu of the conventional model, except possibly for a class of models where the scalar quark masses are generated by radiative corrections from a much larger supersymmetry breaking scale. For a small range of scalar quark and photino mass parameters, the cascade decay process K + → π + π 0 → π + γγ will become dominant over the anti nu nu mode. The author also comments on the possibility of probing the neutrino mass through the K + → π + π 0 → π + anti nu nu cascade decay. Chapter III is concerned with the implications of explicit lepton number violating soft operators in a general low energy effective theory with softly broken supersymmetry

  5. Topics in inflationary cosmology

    International Nuclear Information System (INIS)

    Kahn, R.N.

    1985-01-01

    This thesis examines several topics in the theory of inflationary cosmology. It first proves the existence of Hawking Radiation during the slow-rolling period of a new inflationary universe. It then derives and somewhat extends Bardeen's gauge invariant formalism for calculating the growth of linear gravitational perturbations in a Friedmann-Robertson-Walker cosmological background. This formalism is then applied, first to several new inflationary universe models all of which show a Zel'dovich spectrum of fluctuations, but with amplitude sigma(100 4 ) above observational limits. The general formalism is next applied to models that exhibit primordial inflation. Fluctuations in these models also exhibit a Zel'dovich spectrum here with an acceptable amplitude. Finally the thesis presents the results of new, numerical calculations. A classical, (2 + 1) dimensional computer model is developed that includes a Higgs field (which drives inflation) along with enough auxiliary fields to generate dynamically not only a thermal bath, but also the fluctuations that naturally accompany that bath. The thesis ends with a discussion of future prospects

  6. Advanced verification topics

    CERN Document Server

    Bhattacharya, Bishnupriya; Hall, Gary; Heaton, Nick; Kashai, Yaron; Khan Neyaz; Kirshenbaum, Zeev; Shneydor, Efrat

    2011-01-01

    The Accellera Universal Verification Methodology (UVM) standard is architected to scale, but verification is growing and in more than just the digital design dimension. It is growing in the SoC dimension to include low-power and mixed-signal and the system integration dimension to include multi-language support and acceleration. These items and others all contribute to the quality of the SOC so the Metric-Driven Verification (MDV) methodology is needed to unify it all into a coherent verification plan. This book is for verification engineers and managers familiar with the UVM and the benefits it brings to digital verification but who also need to tackle specialized tasks. It is also written for the SoC project manager that is tasked with building an efficient worldwide team. While the task continues to become more complex, Advanced Verification Topics describes methodologies outside of the Accellera UVM standard, but that build on it, to provide a way for SoC teams to stay productive and profitable.

  7. Topical minoxidil: cardiac effects in bald man.

    Science.gov (United States)

    Leenen, F H; Smith, D L; Unger, W P

    1988-01-01

    Systemic cardiovascular effects during chronic treatment with topical minoxidil vs placebo were evaluated using a double-blind, randomized design for two parallel groups (n = 20 for minoxidil, n = 15 for placebo). During 6 months of follow-up, blood pressure did not change, whereas minoxidil increased heart rate by 3-5 beats min-1. Compared with placebo, topical minoxidil caused significant increases in LV end-diastolic volume, in cardiac output (by 0.751 min-1) and in LV mass (by 5 g m-2). We conclude that in healthy subjects short-term use of topical minoxidil is likely not to be detrimental. However, safety needs to be established regarding ischaemic symptoms in patients with coronary artery disease as well as for the possible development of LV hypertrophy in healthy subjects during years of therapy. PMID:3191000

  8. Percent of Impervious Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — High amounts of impervious cover (parking lots, rooftops, roads, etc.) can increase water runoff, which may directly enter surface water. Runoff from roads often...

  9. GAP Land Cover - Image

    Data.gov (United States)

    Minnesota Department of Natural Resources — This raster dataset is a simple image of the original detailed (1-acre minimum), hierarchically organized vegetation cover map produced by computer classification of...

  10. GAP Land Cover - Vector

    Data.gov (United States)

    Minnesota Department of Natural Resources — This vector dataset is a detailed (1-acre minimum), hierarchically organized vegetation cover map produced by computer classification of combined two-season pairs of...

  11. Percent Wetland Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — Wetlands act as filters, removing or diminishing the amount of pollutants that enter surface water. Higher values for percent of wetland cover (WETLNDSPCT) may be...

  12. Percent Wetland Cover (Future)

    Data.gov (United States)

    U.S. Environmental Protection Agency — Wetlands act as filters, removing or diminishing the amount of pollutants that enter surface water. Higher values for percent of wetland cover (WETLNDSPCT) may be...

  13. Insurance: Covering the bases

    International Nuclear Information System (INIS)

    Burr, M.T.

    1992-01-01

    This article addresses steps to take to improve the economics and risk profiles for independent power projects. The topics discussed in the article include the results of competition in the power industry, custom packages and the lack of competition among insurers in the power industry, mitigating risk through providing technical information, and developing programs

  14. Topics in radiation dosimetry radiation dosimetry

    CERN Document Server

    1972-01-01

    Radiation Dosimetry, Supplement 1: Topics in Radiation Dosimetry covers instruments and techniques in dealing with special dosimetry problems. The book discusses thermoluminescence dosimetry in archeological dating; dosimetric applications of track etching; vacuum chambers of radiation measurement. The text also describes wall-less detectors in microdosimetry; dosimetry of low-energy X-rays; and the theory and general applicability of the gamma-ray theory of track effects to various systems. Dose equivalent determinations in neutron fields by means of moderator techniques; as well as developm

  15. Preface to Special Topic: Marine Renewable Energy

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, F. T.; Iglesias, G.; Santos, P. R.; Deng, Zhiqun

    2015-12-30

    Marine renewable energy (MRE) is generates from waves, currents, tides, and thermal resources in the ocean. MRE has been identified as a potential commercial-scale source of renewable energy. This special topic presents a compilation of works selected from the 3rd IAHR Europe Congress, held in Porto, Portugal, in 2014. It covers different subjects relevant to MRE, including resource assessment, marine energy sector policies, energy source comparisons based on levelized cost, proof-of-concept and new-technology development for wave and tidal energy exploitation, and assessment of possible inference between wave energy converters (WEC).

  16. Preventive Long-Term Effects of a Topical Film-Forming Medical Device with Ultra-High UV Protection Filters and DNA Repair Enzyme in Xeroderma Pigmentosum: A Retrospective Study of Eight Cases

    Directory of Open Access Journals (Sweden)

    Sandra Giustini

    2014-09-01

    Full Text Available Skin cancer is common in xeroderma pigmentosum (XP due to a DNA repair mechanisms genetic defect. Ultraviolet (UV exposure is the main cause of increased incidence of actinic keratosis (AK, basal cell carcinoma (BCC and squamous cell carcinoma (SCC observed in XP subjects. Photoprotection is therefore a mandatory strategy in order to reduce skin damage. A topical DNA repair enzyme has been shown to slow down the development of skin lesions in XP. However, there are no data regarding the effects of photoprotection combined with DNA repair strategies in this clinical setting. A film-forming medical device containing the DNA repair enzyme photolyase and very high-protection UV filters (Eryfotona AK-NMSC, Ery is currently available. We report retrospective data regarding the use of Ery in 8 patients (5 women, 3 men with a diagnosis of XP treated for at least 12 consecutive months, comparing the rate of new skin lesions (AK, BCC and SCC during active treatment with Ery and during 12 months just before the use of the product. New AK, BCC and SCC mean lesion numbers during the 1-year Ery treatment were 5, 3 and 0, respectively in comparison with 14, 6.8 and 3 lesions, respectively during the 1-year pre-treatment period. Ery use was associated with a 65% reduction in appearance of new AK lesions and with 56 and 100% reductions in the incidence of new BCC and SCC lesions, respectively. These data suggest that topical use of photoprotection and DNA repair enzyme could help lower skin cancer lesions in XP. Control prospective trials are advisable in this clinical setting.

  17. Long-term performance of high-voltage insulations. Proceedings. Dauerverhalten von Hochspannungsisolierungen. Vortraege

    Energy Technology Data Exchange (ETDEWEB)

    1985-01-01

    The Conference of the ETG (Energy Eng. Society) covers the following topics: long term performance of epoxide insulations and machine insulations, insulating liquids and mixed dielectrics, fatigue of polyolefine insulation as electrochemical fatigue and possibilities of stabilization. On report was abstracted and classified among 42 articles. (GL).

  18. Topic Modeling of Hierarchical Corpora /

    OpenAIRE

    Kim, Do-kyum

    2014-01-01

    The sizes of modern digital libraries have grown beyond our capacity to comprehend manually. Thus we need new tools to help us in organizing and browsing large corpora of text that do not require manually examining each document. To this end, machine learning researchers have developed topic models, statistical learning algorithms for automatic comprehension of large collections of text. Topic models provide both global and local views of a corpus; they discover topics that run through the co...

  19. Effect meerjarige toepassing groenbemester en organische mest op bodemkwaliteit bij continuteelt maïs : 2e rapport project Zorg voor Zand = Effect of long-term application of cover crops and organic manure on soil quality in a continuous maize production system : 2nd report project Care for Sand

    NARCIS (Netherlands)

    Schooten, van H.A.; Eekeren, van N.J.M.; Hanegraaf, M.C.; Burgt, van der G.J.H.M.; Visser, de M.

    2006-01-01

    In 2005 research was conducted on the effect of long-term application of cover crops and organic manure on various soil quality characteristics in a continuous maize production system on sandy soil. The conclusion was that the effect of organic fertiliser on the quality of the soil and yield was

  20. Climate under cover

    CERN Document Server

    Takakura, Tadashi

    2002-01-01

    1.1. INTRODUCTION Plastic covering, either framed or floating, is now used worldwide to protect crops from unfavorable growing conditions, such as severe weather and insects and birds. Protected cultivation in the broad sense, including mulching, has been widely spread by the innovation of plastic films. Paper, straw, and glass were the main materials used before the era of plastics. Utilization of plastics in agriculture started in the developed countries and is now spreading to the developing countries. Early utilization of plastic was in cold regions, and plastic was mainly used for protection from the cold. Now plastic is used also for protection from wind, insects and diseases. The use of covering techniques started with a simple system such as mulching, then row covers and small tunnels were developed, and finally plastic houses. Floating mulch was an exception to this sequence: it was introduced rather recently, although it is a simple structure. New development of functional and inexpensive films trig...

  1. Cover page.docx

    OpenAIRE

    Gilchrist, Susan

    2016-01-01

    One of the most widely discussed aspects within the topic of sustainability seems to be that of sustainable food consumption (SFC), resulting in interest from the public, governments and the food industry (Vermeir and Verbeke, 2006; Owen, et. al., 2007; OECD, 2008; Salaue, 2010; BIO Intelligence Service, 2012 and Krystallis et. al., 2012). Former research into the areas of environmental and social aspects of sustainable consumption reach the unified conclusion that food c...

  2. On Covering Approximation Subspaces

    Directory of Open Access Journals (Sweden)

    Xun Ge

    2009-06-01

    Full Text Available Let (U';C' be a subspace of a covering approximation space (U;C and X⊂U'. In this paper, we show that and B'(X⊂B(X∩U'. Also, iff (U;C has Property Multiplication. Furthermore, some connections between outer (resp. inner definable subsets in (U;C and outer (resp. inner definable subsets in (U';C' are established. These results answer a question on covering approximation subspace posed by J. Li, and are helpful to obtain further applications of Pawlak rough set theory in pattern recognition and artificial intelligence.

  3. topicmodels: An R Package for Fitting Topic Models

    Directory of Open Access Journals (Sweden)

    Bettina Grun

    2011-05-01

    Full Text Available Topic models allow the probabilistic modeling of term frequency occurrences in documents. The fitted model can be used to estimate the similarity between documents as well as between a set of specified keywords using an additional layer of latent variables which are referred to as topics. The R package topicmodels provides basic infrastructure for fitting topic models based on data structures from the text mining package tm. The package includes interfaces to two algorithms for fitting topic models: the variational expectation-maximization algorithm provided by David M. Blei and co-authors and an algorithm using Gibbs sampling by Xuan-Hieu Phan and co-authors.

  4. Covering tree with stars

    DEFF Research Database (Denmark)

    Baumbach, Jan; Guo, Jian-Ying; Ibragimov, Rashid

    2013-01-01

    We study the tree edit distance problem with edge deletions and edge insertions as edit operations. We reformulate a special case of this problem as Covering Tree with Stars (CTS): given a tree T and a set of stars, can we connect the stars in by adding edges between them such that the resulting ...

  5. Topics in quantum field theory

    NARCIS (Netherlands)

    Dams, C.J.F.

    2006-01-01

    In this PhD-thesis some topics in quantum field theory are considered. The first chapter gives a background to these topics. The second chapter discusses renormalization. In particular it is shown how loop calculations can be performed when using the axial gauge fixing. Fermion creation and

  6. Web directories as topical context

    NARCIS (Netherlands)

    Kaptein, R.; Kamps, J.; Aly, R.; Hauff, C.; den Hamer, I.; Hiemstra, D.; Huibers, T.; de Jong, F.

    2009-01-01

    In this paper we explore whether the Open Directory (or DMOZ) can be used to classify queries into topical categories on different levels and whether we can use this topical context to improve retrieval performance. We have set up a user study to let test persons explicitly classify queries into

  7. Resources for Topics in Architecture.

    Science.gov (United States)

    Van Noate, Judith, Comp.

    This guide for conducting library research on topics in architecture or on the work of a particular architect presents suggestions for utilizing four categories of resources: books, dictionaries and encyclopedias, indexes, and a periodicals and series list (PASL). Two topics are researched as examples: the contemporary architect Richard Meier, and…

  8. Topics in string theory

    Science.gov (United States)

    Jejjala, Vishnumohan

    2002-01-01

    This Thesis explores aspects of superstring theory on orbifold spaces and applies some of the intuition gleaned from the study of the non-commutative geometry of space-time to understanding the fractional quantum Hall effect. The moduli space of vacua of marginal and relevant deformations of N = 4 super-Yang-Mills gauge theory in four dimensions is interpreted in terms of non-commutative geometry. A formalism for thinking about the algebraic geometry of the moduli space is developed. Within this framework, the representation theory of the algebras studied provides a natural exposition of D-brane fractionation. The non-commutative moduli space of deformations preserving N = 1 supersymmetry is examined in detail through various examples. In string theory, by the AdS/CFT correspondence, deformations of the N = 4 field theory are dual to the near-horizon geometries of D-branes on orbifolds of AdS5 x S 5. The physics of D-branes on the dual AdS backgrounds is explored. Quivers encapsulate the matter content of supersymmetric field theories on the worldvolumes of D-branes at orbifold singularities. New techniques for constructing quivers are presented here. When N is a normal subgroup of a finite group G, the quiver corresponding to fixed points of the orbifold M/G is computed from a G/N action on the quiver corresponding to M/G . These techniques prove useful for constructing non-Abelian quivers and for examining discrete torsion orbifolds. Quivers obtained through our constructions contain interesting low-energy phenomenology. The matter content on a brane at an isolated singularity of the Delta27 orbifold embeds the Standard Model. The symmetries of the quiver require exactly three generations of fields in the particle spectrum. Lepton masses are suppressed relative to quark masses because lepton Yukawa couplings do not appear in the superpotential. Lepton masses are generated through the Kahler potential and are related to the supersymmetry breaking scale. The model

  9. Recent advances in topical anesthesia

    Science.gov (United States)

    2016-01-01

    Topical anesthetics act on the peripheral nerves and reduce the sensation of pain at the site of application. In dentistry, they are used to control local pain caused by needling, placement of orthodontic bands, the vomiting reflex, oral mucositis, and rubber-dam clamp placement. Traditional topical anesthetics contain lidocaine or benzocaine as active ingredients and are used in the form of solutions, creams, gels, and sprays. Eutectic mixtures of local anesthesia cream, a mixture of various topical anesthetics, has been reported to be more potent than other anesthetics. Recently, new products with modified ingredients and application methods have been introduced into the market. These products may be used for mild pain during periodontal treatment, such as scaling. Dentists should be aware that topical anesthetics, although rare, might induce allergic reactions or side effects as a result of an overdose. Topical anesthetics are useful aids during dental treatment, as they reduce dental phobia, especially in children, by mitigating discomfort and pain. PMID:28879311

  10. AMNT 2014. Key Topic: Reactor operation, safety - report. Pt. 1

    International Nuclear Information System (INIS)

    Schaffrath, Andreas

    2014-01-01

    Summary report on one session of the Annual Conference on Nuclear Technology held in Frankfurt, 6 to 8 May 2014: - Safety of Nuclear Installations - Methods, Analysis, Results: Backfittings for the Improvement of Safety and Efficiency. The other Sessions of the Key Topics 'Reactor Operation, Safety', 'Competence, Innovation, Regulation' and 'Fuel, Decommissioning and Disposal' will be covered in further issues of atw.

  11. Topic Model for Graph Mining.

    Science.gov (United States)

    Xuan, Junyu; Lu, Jie; Zhang, Guangquan; Luo, Xiangfeng

    2015-12-01

    Graph mining has been a popular research area because of its numerous application scenarios. Many unstructured and structured data can be represented as graphs, such as, documents, chemical molecular structures, and images. However, an issue in relation to current research on graphs is that they cannot adequately discover the topics hidden in graph-structured data which can be beneficial for both the unsupervised learning and supervised learning of the graphs. Although topic models have proved to be very successful in discovering latent topics, the standard topic models cannot be directly applied to graph-structured data due to the "bag-of-word" assumption. In this paper, an innovative graph topic model (GTM) is proposed to address this issue, which uses Bernoulli distributions to model the edges between nodes in a graph. It can, therefore, make the edges in a graph contribute to latent topic discovery and further improve the accuracy of the supervised and unsupervised learning of graphs. The experimental results on two different types of graph datasets show that the proposed GTM outperforms the latent Dirichlet allocation on classification by using the unveiled topics of these two models to represent graphs.

  12. Topical steroid-damaged skin

    Directory of Open Access Journals (Sweden)

    Anil Abraham

    2014-01-01

    Full Text Available Topical steroids, commonly used for a wide range of skin disorders, are associated with side effects both systemic and cutaneous. This article aims at bringing awareness among practitioners, about the cutaneous side effects of easily available, over the counter, topical steroids. This makes it important for us as dermatologists to weigh the usefulness of topical steroids versus their side effects, and to make an informed decision regarding their use in each individual based on other factors such as age, site involved and type of skin disorder.

  13. Selected topics in phenomenology of the standard model

    International Nuclear Information System (INIS)

    Roberts, R.G.

    1991-01-01

    These lectures cover some aspects of phenomenology of topics in high energy physics which advertise the success of the standard model in dealing with a wide variety of experimental data. First we begin with a look at deep inelastic scattering. This tells us about the structure of the nucleon, which is understood in terms of the SU(3) gauge theory of QCD, which then allows the information on quark and gluon distributions to be carried over to other 'hard' processes such as hadronic production of jets. Recent data on electroweak processes can estimate the value of Sin 2 θw to a precision where the inclusion of radiative corrections allow bounds to be made on the mass of the top quark. Electroweak effects arise in e + e - collisions, but we first present a review of the recent history of this topic within the context of QCD. We bring the subject up to date with a look at the physics at (or near) the Z pole where the measurement of asymmetries can give more information. We look at the conventional description of quark mixing by the CKM matrix and see how the mixing parameters are systematically being extracted from a variety of reactions and decays. In turn, the values can be used to set bounds on the top quark mass. The matter of CP violation in weak interactions is addressed within the context of the standard model, recent data on ε'/ε being the source of current excitement. Finally, we at the theoretical description and experimental efforts to search for the top quark. (author)

  14. Topics in Theoretical Physics

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, Andrew [Boston Univ., MA (United States); Schmaltz, Martin [Boston Univ., MA (United States); Katz, Emmanuel [Boston Univ., MA (United States); Rebbi, Claudio [Boston Univ., MA (United States); Glashow, Sheldon [Boston Univ., MA (United States); Brower, Richard [Boston Univ., MA (United States); Pi, So-Young [Boston Univ., MA (United States)

    2016-09-30

    decay rates which can confirm or rule out the surprising results from the earlier LHC data. The most recent and precise measurements of the cosmic microwave background from the Planck satellite, from a combination of measurements of the dark matter distribution in the universe, and from a measurement of the expansion rate of the universe today show some disagreement when interpreted in terms of the so-called LambdaCDM model. Schmaltz and collaborators proposed an alternative model to LambdaCDM in which the usual cold dark matter is replaced by a new ``dark sector". This sector consists of a cold dark matter particle which interacts with a newly postulated dark radiation component of the universe. The dark radiation can help explain the discrepancy in measurements of the expansion rate, and the dark matter interactions subtly modify the clumping of dark matter at large scales, thus potentially explaining both kinds of tensions in the data. In two publications Schmaltz described the new model and then performed a precision comparison of the predictions of the model with all currently available cosmological data. The results favor the new model at the level of three standard deviations with current data. Quantum Field Theory (QFT) is the language we use to describe quantum systems which are consistent with Einstein’s theory of Special Relativity. In particular, the requirement of Einstein’s theory that signals not travel faster than the speed of light constrains the types of interactions which particles can engage in. One consequence of relativity is that these interactions cannot preserve particle number. The stronger the interactions, the more severe the particle number violation in a given Relativistic QFT. When particle number violation is strong, it becomes very difficult to adequately parameterize the quantum wave function (which characterizes the state of a quantum system). For example, though we can formulate the QFT which describes the strong force as a set of

  15. Topics in Theoretical Physics

    International Nuclear Information System (INIS)

    Cohen, Andrew; Schmaltz, Martin; Katz, Emmanuel; Rebbi, Claudio; Glashow, Sheldon; Brower, Richard; Pi, So-Young

    2016-01-01

    confirm or rule out the surprising results from the earlier LHC data. The most recent and precise measurements of the cosmic microwave background from the Planck satellite, from a combination of measurements of the dark matter distribution in the universe, and from a measurement of the expansion rate of the universe today show some disagreement when interpreted in terms of the so-called LambdaCDM model. Schmaltz and collaborators proposed an alternative model to LambdaCDM in which the usual cold dark matter is replaced by a new 'dark sector'. This sector consists of a cold dark matter particle which interacts with a newly postulated dark radiation component of the universe. The dark radiation can help explain the discrepancy in measurements of the expansion rate, and the dark matter interactions subtly modify the clumping of dark matter at large scales, thus potentially explaining both kinds of tensions in the data. In two publications Schmaltz described the new model and then performed a precision comparison of the predictions of the model with all currently available cosmological data. The results favor the new model at the level of three standard deviations with current data. Quantum Field Theory (QFT) is the language we use to describe quantum systems which are consistent with Einstein's theory of Special Relativity. In particular, the requirement of Einstein's theory that signals not travel faster than the speed of light constrains the types of interactions which particles can engage in. One consequence of relativity is that these interactions cannot preserve particle number. The stronger the interactions, the more severe the particle number violation in a given Relativistic QFT. When particle number violation is strong, it becomes very difficult to adequately parameterize the quantum wave function (which characterizes the state of a quantum system). For example, though we can formulate the QFT which describes the strong force as a set of interactions between quark

  16. Topic structure for information retrieval

    NARCIS (Netherlands)

    He, J.; Sanderson, M.; Zhai, C.; Zobel, J.; Allan, J.; Aslam, J.A.

    2009-01-01

    In my research, I propose a coherence measure, with the goal of discovering and using topic structures within and between documents, of which I explore its extensions and applications in information retrieval.

  17. Selected topics in nuclear structure

    International Nuclear Information System (INIS)

    1994-01-01

    The collection of abstracts on selected topics in nuclear structure are given. Special attention pays to collective excitations and high-spin states of nuclei, giant resonance structure, nuclear reaction mechanisms and so on

  18. Sentiment topic mining based on comment tags

    Science.gov (United States)

    Zhang, Daohai; Liu, Xue; Li, Juan; Fan, Mingyue

    2018-03-01

    With the development of e-commerce, various comments based on tags are generated, how to extract valuable information from these comment tags has become an important content of business management decisions. This study takes HUAWEI mobile phone tags as an example using the sentiment analysis and topic LDA mining method. The first step is data preprocessing and classification of comment tag topic mining. And then make the sentiment classification for comment tags. Finally, mine the comments again and analyze the emotional theme distribution under different sentiment classification. The results show that HUAWEI mobile phone has a good user experience in terms of fluency, cost performance, appearance, etc. Meanwhile, it should pay more attention to independent research and development, product design and development. In addition, battery and speed performance should be enhanced.

  19. Topics in modern differential geometry

    CERN Document Server

    Verstraelen, Leopold

    2017-01-01

    A variety of introductory articles is provided on a wide range of topics, including variational problems on curves and surfaces with anisotropic curvature. Experts in the fields of Riemannian, Lorentzian and contact geometry present state-of-the-art reviews of their topics. The contributions are written on a graduate level and contain extended bibliographies. The ten chapters are the result of various doctoral courses which were held in 2009 and 2010 at universities in Leuven, Serbia, Romania and Spain.

  20. Covering tree with stars

    DEFF Research Database (Denmark)

    Baumbach, Jan; Guo, Jiong; Ibragimov, Rashid

    2015-01-01

    We study the tree edit distance problem with edge deletions and edge insertions as edit operations. We reformulate a special case of this problem as Covering Tree with Stars (CTS): given a tree T and a set of stars, can we connect the stars in by adding edges between them such that the resulting...... tree is isomorphic to T? We prove that in the general setting, CST is NP-complete, which implies that the tree edit distance considered here is also NP-hard, even when both input trees having diameters bounded by 10. We also show that, when the number of distinct stars is bounded by a constant k, CTS...

  1. Alternate cover materials

    International Nuclear Information System (INIS)

    1988-09-01

    As an effort to enhance compliance with the proposed US Environmental Protection Agency (EPA) groundwater standards, several special studies are being performed by the Technical Assistance Contractor (TAC) to identify and evaluate various design features that may reduce groundwater-related releases from tailings piles. The objective of this special study is to assess the suitability of using alternate cover materials (other than geomembranes) as infiltration barriers in Uranium Mill Tailings Remedial Action (UMTRA) Project piles to minimize leachate generation. The materials evaluated in this study include various types of asphalts, concretes, and a sodium bentonite clay/polypropylene liner system

  2. Selected topics of fluid mechanics

    Science.gov (United States)

    Kindsvater, Carl E.

    1958-01-01

    The fundamental equations of fluid mechanics are specific expressions of the principles of motion which are ascribed to Isaac Newton. Thus, the equations which form the framework of applied fluid mechanics or hydraulics are, in addition to the equation of continuity, the Newtonian equations of energy and momentum. These basic relationships are also the foundations of river hydraulics. The fundamental equations are developed in this report with sufficient rigor to support critical examinations of their applicability to most problems met by hydraulic engineers of the Water Resources Division of the United States Geological Survey. Physical concepts are emphasized, and mathematical procedures are the simplest consistent with the specific requirements of the derivations. In lieu of numerical examples, analogies, and alternative procedures, this treatment stresses a brief methodical exposition of the essential principles. An important objective of this report is to prepare the user to read the literature of the science. Thus, it begins With a basic vocabulary of technical symbols, terms, and concepts. Throughout, emphasis is placed on the language of modern fluid mechanics as it pertains to hydraulic engineering. The basic differential and integral equations of simple fluid motion are derived, and these equations are, in turn, used to describe the essential characteristics of hydrostatics and piezometry. The one-dimensional equations of continuity and motion are defined and are used to derive the general discharge equation. The flow net is described as a means of demonstrating significant characteristics of two-dimensional irrotational flow patterns. A typical flow net is examined in detail. The influence of fluid viscosity is described as an obstacle to the derivation of general, integral equations of motion. It is observed that the part played by viscosity is one which is usually dependent on experimental evaluation. It follows that the dimensionless ratios known as

  3. Specialists' meeting on fast reactor cover gas purification

    International Nuclear Information System (INIS)

    1987-01-01

    The tentative agenda was adopted by the participants without comment and was followed throughout the meeting. The following topics were discussed at the subsequent sessions of the meeting on 'Fast Reactor Cover Gas Purification': National Position Papers; Impurities: Sources and Measurement; Cover Gas Purification Techniques; Sodium Aerosol Trapping; Radiological Considerations. Based on the papers presented and the discussions following, session summaries and conclusions were prepared and are included in this report

  4. Specialists' meeting on fast reactor cover gas purification

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1987-07-01

    The tentative agenda was adopted by the participants without comment and was followed throughout the meeting. The following topics were discussed at the subsequent sessions of the meeting on 'Fast Reactor Cover Gas Purification': National Position Papers; Impurities: Sources and Measurement; Cover Gas Purification Techniques; Sodium Aerosol Trapping; Radiological Considerations. Based on the papers presented and the discussions following, session summaries and conclusions were prepared and are included in this report.

  5. Application of willis covered stent in the treatment of aneurysms located in the cisternal segment of the internal carotid artery: a pilot comparative study with long-term follow-up results

    International Nuclear Information System (INIS)

    Zhu Yueqi; Li Minghua; Fang Chun; Wang Wu; Zhang Peilei; Cheng Yingsheng; Tan Huaqiao; Wang Jianbo

    2010-01-01

    Objective: Complicated aneurysms located in the cisternal segment of the internal carotid artery(ICA-CSA) present unique therapeutic difficulties. This study is to discuss the feasibility of the Willis stent-graft in treating complicated ICA-CSA by comparing its effect with that of coiling therapy. Methods: Willis covered stents were employed in 19 complicated ICA-CSAs (group A), while coils were used in 17 complicated ICA-CSAs (group B). Follow-up angiography was performed to investigate aneurysm recurrence, endoleak and parent artery (PA) stenosis. Kaplan-Meier curves were constructed to compare the recurrence-free and PA stenosis-free rate in both groups. Results: Total exclusion was immediately achieved in 13 ICA-CSAs and minor endoleaks presented in 5 cases in group A. Total or near-total occlusion was achieved in 7 ICA-CSAs, subtotal occlusion in 8 and partial occlusion in 2 cases in group B after coiling. Acute thrombosis occurred in 1 patient in either group and re-hemorrhage happened in 1 patient after coiling. Follow-up angiography in group A revealed that 16 ICA-CSAs were completely isolated, with two parent arteries showing mild in-stent stenosis. Eighteen months after the procedure, Kaplan-Meier analysis showed that the recurrence-free rate was 93.3% and 50%, while the stenosis-free rate of parent artery was 87.5% and 100% in group A and in Group B, respectively. In group A and group Bthe clinical neurological symptoms were fully recovered in 9 and 9, obviously improved in 3 and 5, unchanged in 2 and 2, and aggravated in one and 0 patients, respectively. Conclusion: The implantation of Willis stent-graft is a feasible endovascular therapy for complicated ICA-CSAs. When the parent artery is very tortuous or when the risk that a main collateral branch may be wrongly covered and occluded is present, the implantation of Willis covered stent can not be taken as the treatment of first choice. (authors)

  6. Developments in functional equations and related topics

    CERN Document Server

    Ciepliński, Krzysztof; Rassias, Themistocles

    2017-01-01

    This book presents current research on Ulam stability for functional equations and inequalities. Contributions from renowned scientists emphasize fundamental and new results, methods and techniques. Detailed examples are given to theories to further understanding at the graduate level for students in mathematics, physics, and engineering. Key topics covered in this book include: Quasi means Approximate isometries Functional equations in hypergroups Stability of functional equations Fischer-Muszély equation Haar meager sets and Haar null sets Dynamical systems Functional equations in probability theory Stochastic convex ordering Dhombres functional equation Nonstandard analysis and Ulam stability This book is dedicated in memory of Staniłsaw Marcin Ulam, who posed the fundamental problem concerning approximate homomorphisms of groups in 1940; which has provided the stimulus for studies in the stability of functional equations and inequalities.

  7. Deep Unfolding for Topic Models.

    Science.gov (United States)

    Chien, Jen-Tzung; Lee, Chao-Hsi

    2018-02-01

    Deep unfolding provides an approach to integrate the probabilistic generative models and the deterministic neural networks. Such an approach is benefited by deep representation, easy interpretation, flexible learning and stochastic modeling. This study develops the unsupervised and supervised learning of deep unfolded topic models for document representation and classification. Conventionally, the unsupervised and supervised topic models are inferred via the variational inference algorithm where the model parameters are estimated by maximizing the lower bound of logarithm of marginal likelihood using input documents without and with class labels, respectively. The representation capability or classification accuracy is constrained by the variational lower bound and the tied model parameters across inference procedure. This paper aims to relax these constraints by directly maximizing the end performance criterion and continuously untying the parameters in learning process via deep unfolding inference (DUI). The inference procedure is treated as the layer-wise learning in a deep neural network. The end performance is iteratively improved by using the estimated topic parameters according to the exponentiated updates. Deep learning of topic models is therefore implemented through a back-propagation procedure. Experimental results show the merits of DUI with increasing number of layers compared with variational inference in unsupervised as well as supervised topic models.

  8. Interrelationships between soil cover and plant cover depending on land use

    Directory of Open Access Journals (Sweden)

    Tiina Köster

    2013-05-01

    Full Text Available Interrelationships between soil cover and plant cover of normally developed (or postlithogenic mineral soils are analysed on the basis of four sampling soil groups. The four-link pedo-ecological sequence of analysed soils, rendzinas → brown soils → pseudopodzolic soils → gley-podzols, forms a representative cross section in relation to the normal mineral soils of Estonia. All groups differ substantially from each other in terms of soil properties (calcareousness, acidity, nutrition conditions, profile fabric and humus cover. The primary tasks of the research were (1 to elucidate the main pedo-ecological characteristics of the four soil groups and their suitability for plant cover, (2 to evaluate comparatively soils in terms of productivity, sustainability, biodiversity and environmental protection ability and (3 to analyse possibilities for ecologically sound matching of soil cover with suitable plant cover. On the basis of the same material, the influence of land-use change on humus cover (epipedon fabric, properties of the entire soil cover and soil–plant interrelationship were also analysed. An ecosystem approach enables us to observe particularities caused by specific properties of a soil type (species, variety in biological turnover and in the formation of biodiversity.

  9. Topics in the generalized vector dominance model

    International Nuclear Information System (INIS)

    Chavin, S.

    1976-01-01

    Two topics are covered in the generalized vector dominance model. In the first topic a model is constructed for dilepton production in hadron-hadron interactions based on the idea of generalized vector-dominance. It is argued that in the high mass region the generalized vector-dominance model and the Drell-Yan parton model are alternative descriptions of the same underlying physics. In the low mass regions the models differ; the vector-dominance approach predicts a greater production of dileptons. It is found that the high mass vector mesons which are the hallmark of the generalized vector-dominance model make little contribution to the large yield of leptons observed in the transverse-momentum range 1 less than p/sub perpendicular/ less than 6 GeV. The recently measured hadronic parameters lead one to believe that detailed fits to the data are possible under the model. The possibility was expected, and illustrated with a simple model the extreme sensitivity of the large-p/sub perpendicular/ lepton yield to the large-transverse-momentum tail of vector-meson production. The second topic is an attempt to explain the mysterious phenomenon of photon shadowing in nuclei utilizing the contribution of the longitudinally polarized photon. It is argued that if the scalar photon anti-shadows, it could compensate for the transverse photon, which is presumed to shadow. It is found in a very simple model that the scalar photon could indeed anti-shadow. The principal feature of the model is a cancellation of amplitudes. The scheme is consistent with scalar photon-nucleon data as well. The idea is tested with two simple GVDM models and finds that the anti-shadowing contribution of the scalar photon is not sufficient to compensate for the contribution of the transverse photon. It is found doubtful that the scalar photon makes a significant contribution to the total photon-nuclear cross section

  10. Quantum mechanics II advanced topics

    CERN Document Server

    Rajasekar, S

    2015-01-01

    Quantum Mechanics II: Advanced Topics uses more than a decade of research and the authors’ own teaching experience to expound on some of the more advanced topics and current research in quantum mechanics. A follow-up to the authors introductory book Quantum Mechanics I: The Fundamentals, this book begins with a chapter on quantum field theory, and goes on to present basic principles, key features, and applications. It outlines recent quantum technologies and phenomena, and introduces growing topics of interest in quantum mechanics. The authors describe promising applications that include ghost imaging, detection of weak amplitude objects, entangled two-photon microscopy, detection of small displacements, lithography, metrology, and teleportation of optical images. They also present worked-out examples and provide numerous problems at the end of each chapter.

  11. Topical application of hemostatic paste

    Directory of Open Access Journals (Sweden)

    Mohammad Mizanur Rahman

    2017-02-01

    Full Text Available As a measure to control minor surgical bleeding, surgeons usually depend on a number of hemostatic aids. Topical use of bovine thrombin is a widely used procedure to arrest such minor bleeding. A 35 year old male sergeant of Bangladesh Air Force presented with repeated development of hematoma in his left thigh without any history of trauma or previous history of bleeding. Critical analysis of the patient’s history, routine and sophisticated hematological investigations revealed that the patient developed anti-thrombin antibody following the application of hemostatic paste in the tooth socket five years back during minor dental procedure to stop ignorable bleeding episodes. Therefore, topical use of hemostatic glue/paste or bovine thrombin should be avoided to desist minor bleeding as recombinant human thrombin is now available for topical use.

  12. Armenian media coverage of science topics

    Science.gov (United States)

    Mkhitaryan, Marie

    2016-12-01

    The article discusses features and issues of Armenian media coverage on scientific topics and provides recommendations on how to promote scientific topics in media. The media is more interested in social or public reaction rather than in scientific information itself. Medical science has a large share of the global media coverage. It is followed by articles about environment, space, technology, physics and other areas. Armenian media mainly tends to focus on a scientific topic if at first sight it contains something revolutionary. Media primarily reviews whether that scientific study can affect the Armenian economy and only then decides to refer to it. Unfortunately, nowadays the perception of science is a little distorted in media. We can often see headlines of news where is mentioned that the scientist has made "an invention". Nowadays it is hard to see the border between a scientist and an inventor. In fact, the technological term "invention" attracts the media by making illusionary sensation and ensuring large audience. The report also addresses the "Gitamard" ("A science-man") special project started in 2016 in Mediamax that tells about scientists and their motivations.

  13. Selected topics in nuclear structure

    International Nuclear Information System (INIS)

    Solov'ev, V.G.; Gromov, K.Ya.; Malov, L.A.; Shilov, V.M.

    1994-01-01

    The Fourth International Conference on selected topics in nuclear structure was held at Dubna in July 1994 on recent experimental and theoretical investigations in nuclear structure. Topics discussed were the following: nuclear structure at low-energy excitations (collective quasiparticle phenomena, proton-neutron interactions, microscopic and phenomenological theories of nuclear structure; nuclear structure studies with charged particles. heavy ions, neutrons and photons; nuclei at high angular momenta and superdeformation, structure and decay properties of giant resonances, charge-exchange resonances and β-decay; semiclassical approach of large amplitude collective motion and structure of hot nuclei

  14. Topics in millimeter wave technology

    CERN Document Server

    Button, Kenneth

    1988-01-01

    Topics in Millimeter Wave Technology, Volume 1 presents topics related to millimeter wave technology, including fin-lines and passive components realized in fin-lines, suspended striplines, suspended substrate microstrips, and modal power exchange in multimode fibers. A miniaturized monopulse assembly constructed in planar waveguide with multimode scalar horn feeds is also described. This volume is comprised of five chapters; the first of which deals with the analysis and synthesis techniques for fin-lines as well as the various passive components realized in fin-line. Tapers, discontinuities,

  15. Selected topics in nuclear structure

    Energy Technology Data Exchange (ETDEWEB)

    Solov` ev, V G; Gromov, K Ya; Malov, L A; Shilov, V M

    1994-12-31

    The Fourth International Conference on selected topics in nuclear structure was held at Dubna in July 1994 on recent experimental and theoretical investigations in nuclear structure. Topics discussed were the following: nuclear structure at low-energy excitations (collective quasiparticle phenomena, proton-neutron interactions, microscopic and phenomenological theories of nuclear structure; nuclear structure studies with charged particles). heavy ions, neutrons and photons; nuclei at high angular momenta and superdeformation, structure and decay properties of giant resonances, charge-exchange resonances and {beta}-decay; semiclassical approach of large amplitude collective motion and structure of hot nuclei.

  16. National Land Cover Database (NLCD) Land Cover Collection

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The National Land Cover Database (NLCD) Land Cover Collection is produced through a cooperative project conducted by the Multi-Resolution Land Characteristics (MRLC)...

  17. Dressings and topical agents for surgical wounds healing by secondary intention

    NARCIS (Netherlands)

    Vermeulen, H.; Ubbink, D.; Goossens, A.; de Vos, R.; Legemate, D.

    2004-01-01

    BACKGROUND: Many different wound dressings and topical applications are used to cover surgical wounds healing by secondary intention. It is not known whether these dressings heal wounds at different rates. OBJECTIVES: To assess the effectiveness of dressings and topical agents on surgical wounds

  18. MANAGEMENT EFFECTS ON GROUND COVER CLUMPINESS: SCALING FROM FIELD TO SENTINEL-2 COVER ESTIMATES

    Directory of Open Access Journals (Sweden)

    P. Scarth

    2017-11-01

    Full Text Available Significant progress has been made in the development of cover data and derived products based on remotely sensed fractional cover information and field data across Australia, and these cover data sets are now used for quantifying and monitoring grazing land condition. The availability of a dense time-series of nearly 30 years of cover data to describe the spatial and temporal patterns in landscape changes over time can help with monitoring the effectiveness of grazing land management practice change. With the advent of higher spatial resolution data, such as that provided by the Copernicus Sentinel 2 series of satellites, we can look beyond reporting purely on cover amount and more closely at the operational monitoring and reporting on spatial arrangement of cover and its links with land condition. We collected high spatial resolution cover transects at 20 cm intervals over the Wambiana grazing trials in the Burdekin catchment in Queensland, Australia. Spatial variance analysis was used to determine the cover autocorrelation at various support intervals. Coincident Sentinel-2 imagery was collected and processed over all the sites providing imagery to link with the field data. We show that the spatial arrangement and temporal dynamics of cover are important indicators of grazing land condition for both productivity and water quality outcomes. The metrics and products derived from this research will assist land managers to prioritize investment and practice change strategies for long term sustainability and improved water quality, particularly in the Great Barrier Reef catchments.

  19. Safety and Health Topics: Lead

    Science.gov (United States)

    ... ammunition, pipes, cable covering, building material, solder, radiation shielding, collapsible tubes, and fishing weights. Lead is also ... lead linings in tanks and radiation protection, leaded glass, work involving soldering, and other work involving lead ...

  20. Selected topics in grand unification

    International Nuclear Information System (INIS)

    Seckel, D.

    1983-01-01

    This dissertation is a collection of four pieces of research dealing with grand unification. The topics are neutron oscillation, CP violation, magnetic monopole abundance and distribution in neutron stars, and a proposal for an inflationary cosmology driven by stress-energy in domain walls

  1. Topics in elementary particle physics

    International Nuclear Information System (INIS)

    Dugan, M.J.

    1985-01-01

    Topics in elementary particle physics are discussed. Models with N = 2 supersymmetry are constructed. The CP violation properties of a class of N = 1 supergravity models are analyzed. The structure of a composite Higgs model is investigated. The implications of a 17 keV neutrino are considered

  2. Resources for Topics in Nursing.

    Science.gov (United States)

    Riordan, Dale B.

    This guide is intended to help the user become familiar with a selected group of reference tools and resources which are useful in nursing education and practice. It is important for students to use the correct medical or scientific terminology, understand the scope of a topic, and then utilize the tools necessary to research subjects of interest.…

  3. Seven topics in perturbative QCD

    International Nuclear Information System (INIS)

    Buras, A.J.

    1980-09-01

    The following topics of perturbative QCD are discussed: (1) deep inelastic scattering; (2) higher order corrections to e + e - annihilation, to photon structure functions and to quarkonia decays; (3) higher order corrections to fragmentation functions and to various semi-inclusive processes; (4) higher twist contributions; (5) exclusive processes; (6) transverse momentum effects; (7) jet and photon physics

  4. Selected topics in nuclear structure

    International Nuclear Information System (INIS)

    Stachura, Z.

    1984-09-01

    19. winter school in Zakopane was devoted to selected topics in nuclear structure such as: production of spin resonances, heavy ions reactions and their applications to the investigation of high spin states, octupole deformations, excited states and production of new elements etc. The experimental data are ofen compared with theoretical predictions. Report contains 28 papers. (M.F.W.)

  5. Hot Topics in Science Teaching

    Science.gov (United States)

    Ediger, Marlow

    2018-01-01

    There are vital topics in science teaching and learning which are mentioned frequently in the literature. Specialists advocate their importance in the curriculum as well as science teachers stress their saliency. Inservice education might well assist new and veteran teachers in knowledge and skills. The very best science lessons and units of…

  6. Topic Map for Authentic Travel

    OpenAIRE

    Wandsvik, Atle; Zare, Mehdi

    2007-01-01

    E-business is a new trend in Internet use. Authentic travel is an approach to travel and travel business which helps the traveler experience what is authentic in the travel destination. But how can the traveler find those small authentic spots and organize them together to compose a vacation? E-business techniques, combined withTopic Maps, can help.

  7. Two topics in quantum chromodynamics

    International Nuclear Information System (INIS)

    Bjorken, J.D.

    1989-12-01

    The two topics are (1) estimates of perturbation theory coefficients for R(e + e - → hadrons), and (2) the virtual-photon structure function, with emphasis on the analytic behavior in its squared mass. 20 refs., 4 figs., 2 tabs

  8. Analyzing research trends on drug safety using topic modeling.

    Science.gov (United States)

    Zou, Chen

    2018-04-06

    Published drug safety data has evolved in the past decade due to scientific and technological advances in the relevant research fields. Considering that a vast amount of scientific literature has been published in this area, it is not easy to identify the key information. Topic modeling has emerged as a powerful tool to extract meaningful information from a large volume of unstructured texts. Areas covered: We analyzed the titles and abstracts of 4347 articles in four journals dedicated to drug safety from 2007 to 2016. We applied Latent Dirichlet allocation (LDA) model to extract 50 main topics, and conducted trend analysis to explore the temporal popularity of these topics over years. Expert Opinion/Commentary: We found that 'benefit-risk assessment and communication', 'diabetes' and 'biologic therapy for autoimmune diseases' are the top 3 most published topics. The topics relevant to the use of electronic health records/observational data for safety surveillance are becoming increasingly popular over time. Meanwhile, there is a slight decrease in research on signal detection based on spontaneous reporting, although spontaneous reporting still plays an important role in benefit-risk assessment. The topics related to medical conditions and treatment showed highly dynamic patterns over time.

  9. Allegheny County Land Cover Areas

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — The Land Cover dataset demarcates 14 land cover types by area; such as Residential, Commercial, Industrial, Forest, Agriculture, etc. If viewing this description on...

  10. Covering all the bases

    Energy Technology Data Exchange (ETDEWEB)

    Offen, G.; Shick, N.; Chang, R. (and others) [EPRI (US)

    2004-10-01

    Mercury control technologies offering sustainable performance and known applicability, impact, and cost are still in the future. Cooperative funding for long-term, full-scale tests of developed technologies and support for merging ones, promises to close this gap. The goal is to learn how to tailor mercury control technologies to the flue gas environments of individual coal-fired power plants. The article describes the current performance of mercury control technologies and discusses the research needed to support their success. 4 figs.

  11. On approximating restricted cycle covers

    NARCIS (Netherlands)

    Manthey, Bodo

    2008-01-01

    A cycle cover of a graph is a set of cycles such that every vertex is part of exactly one cycle. An $L$-cycle cover is a cycle cover in which the length of every cycle is in the set $L$. The weight of a cycle cover of an edge-weighted graph is the sum of the weights of its edges. We come close to

  12. AMNT 2014. Key topic: Reactor operation, safety - report. Pt. 2

    International Nuclear Information System (INIS)

    Fischer, Klaus-Christian; Willschuetz, Hans-Georg; Wortmann, Birgit

    2014-01-01

    Summary report on the following sessions of the Annual Conference on Nuclear Technology held in Frankfurt, 6 to 8 May 2014: - Thermo Dynamics and Fluid Dynamics: Experiments and Backfittings for the Improvement of Safety and Efficiency; - Safety of Nuclear Installations - Methods, Analyses, Results: In-Vessel Phenomena; Ex-Vessel Phenomena; - Standards and Regulations; Hazard and Safety Analysis; and Validation and Uncertainty Analysis. The other Sessions of the Key Topics 'Reactor Operation, Safety', 'Competence, Innovation, Regulation' and 'Fuel, Decommissioning and Disposal' have been covered in atw 10 (2014) and will be covered in further issues of atw.

  13. AMNT 2014. Key topic: Reactor operation, safety - report. Pt. 3

    Energy Technology Data Exchange (ETDEWEB)

    Bohnstedt, Angelika [Karlsruher Institut fuer Technologie (KIT), Eggenstein-Leopoldshafen (Germany). Programm Nukleare Sicherheitsforschung (NUKLEAR); Mull, Thomas [AREVA GmbH, Erlangen (Germany). Nuclear Fusion, HTR and Transverse Issues (PTDH-G); Starflinger, Joerg [Stuttgart Univ. (Germany). Inst. fuer Kernenergetik und Energiesysteme (IKE)

    2015-01-15

    Summary report on the following sessions of the Annual Conference on Nuclear Technology held in Frankfurt, 6 to 8 May 2014: - Reactor Operation, Safety: Radiation Protection (Angelika Bohnstedt); - Competence, Innovation, Regulation: Fusion Technology - Optimisation Steps in the ITER Design (Thomas Mull); - Competence, Innovation, Regulation: Education, Expert Knowledge, Knowledge Transfer (Joerg Starflinger). The other Sessions of the Key Topics 'Reactor Operation, Safety', 'Competence, Innovation, Regulation' and 'Fuel, Decommissioning and Disposal' have been covered in atw 10 and 12 (2015) and will be covered in further issues of atw.

  14. Scenarios of land cover in China

    Science.gov (United States)

    Yue, Tian Xiang; Fan, Ze Meng; Liu, Ji Yuan

    2007-02-01

    A method for surface modeling of land cover change (SMLC) is developed on the basis of establishing transition probability matrixes between land cover types and HLZ types. SMLC is used to simulate land cover scenarios of China for the years 2039, 2069 and 2099, for which HLZ scenarios are first simulated in terms of HadCM3 climatic scenarios that are downscaled in zonal model of spatial climate change in China. This paper also analyzes spatial distribution of land cover types, area change and mean center shift of each land cover type, ecotope diversity, and patch connectivity under the land cover scenarios. The results show that cultivated land would decrease and woodland would expand greatly with climatic change, which coincides with consequences expected by implementation of Grain-for-Green policy. Nival area would shrink, and desertification area would expand at a comparatively slow rate in future 100 years. Climate change would generally cause less ecotope diversity and more patch connectivity. Ecosystems in China would have a pattern of beneficial cycle after efficient ecological conservation and restoration. However, if human activities would exceed regulation capacity of ecosystems themselves, the ecosystems in China might deteriorate more seriously.

  15. Texasgulf solar cogeneration program. Mid-term topical report

    Energy Technology Data Exchange (ETDEWEB)

    1981-02-01

    The status of technical activities of the Texasgulf Solar Cogeneration Program at the Comanche Creek Sulfur Mine is described. The program efforts reported focus on preparation of a system specification, selection of a site-specific configuration, conceptual design, and facility performance. Trade-off studies performed to select the site-specific cogeneration facility configuration that would be the basis for the conceptual design efforts are described. Study areas included solar system size, thermal energy storage, and field piping. The conceptual design status is described for the various subsystems of the Comanche Creek cogeneration facility. The subsystems include the collector, receiver, master control, fossil energy, energy storage, superheat boiler, electric power generation, and process heat subsystems. Computer models for insolation and performance are also briefly discussed. Appended is the system specification. (LEW)

  16. Gainesville's urban forest canopy cover

    Science.gov (United States)

    Francisco Escobedo; Jennifer A. Seitz; Wayne Zipperer

    2009-01-01

    Ecosystem benefits from trees are linked directly to the amount of healthy urban forest canopy cover. Urban forest cover is dynamic and changes over time due to factors such as urban development, windstorms, tree removals, and growth. The amount of a city's canopy cover depends on its land use, climate, and people's preferences. This fact sheet examines how...

  17. Preparing for the future today: The findings of the NEA RK and M initiative for the short term (This period covers several decades and likely more than 100 years. The actual duration will vary across national programmes)

    International Nuclear Information System (INIS)

    Schroeder, Jantine

    2015-01-01

    The NEA initiative on Records, Knowledge and Memory (RK and M) across Generations is an initiative that expresses, supports and aims to answer to an evolution in long-term radioactive waste management (RWM) thinking over the past decades. In the earlier days, the vision seems to have been that waste management ends with the closure of disposal sites. Oversight after closure was not an issue that was studied, (tacitly) assuming safe oblivion of geological repositories, or that archives, markers and other similar tools would suffice, e.g. to avoid human intrusion and/or to understand the nature of the underground facility. Today, it is recognised that oversight should take place for as long as practicable. The new vision includes the preservation of information to be used by future generations. In this paper we want to highlight that such a vision shift with regard to the future requires an accompanying shift with regard to present thinking and practices. To this aim, we will outline some of the studies undertaken within the RK and M initiative that substantiate this finding that the future starts today, and offer suggestions to support its concretization. societal oversight as long as practicable, we should acknowledge the fact that RK and M loss takes place rapidly if it is not acted upon in a conscious and ongoing manner that involves various actors and does more than dumping records into archives. The success of RK and M preservation cannot be judged today by whether they will last for one or ten thousand years. Instead, it lies in establishing and maintaining awareness of the need and responsibility for RK and M preservation in the minds of regulators, operators, stakeholders and, especially in the longer term, the local and regional authorities and general public. Therefore, we should not only think about future activities, but act upon the idea that the long term starts today, and that RK and M preservation needs to be prepared for in the present, while the

  18. The value of snow cover

    Science.gov (United States)

    Sokratov, S. A.

    2009-04-01

    Snow is the natural resource, like soil and water. It has specific properties which allow its use not just for skiing but also for houses cooling in summer (Swedish experience), for air fields construction (Arctic and Antarctic), for dams (north of Russia), for buildings (not only snow-houses of some Polar peoples but artistic hotel attracting tourists in Sweden), and as art material (Sapporo snow festival, Finnish events), etc. "Adjustment" of snow distribution and amount is not only rather common practice (avalanche-protection constructions keeping snow on slopes) but also the practice with long history. So-called "snow irrigation" was used in Russia since XIX century to protect winter crop. What is now named "artificial snow production", is part of much larger pattern. What makes it special—it is unavoidable in present climate and economy situation. 5% of national income in Austria is winter tourism. 50% of the economy in Savoy relay on winter tourism. In terms of money this can be less, but in terms of jobs and income involved this would be even more considerable in Switzerland. As an example—the population of Davos is 14000 in Summer and 50000 in Winter. Skiing is growing business. In present time you can find ski slopes in Turkey and Lebanon. To keep a cite suitable for attracting tourists you need certain amount of sunny days and certain amount of snow. The snow cannons are often the only way to keep a place running. On the other hand, more artificial snow does not necessary attract more tourists, while heavy natural snowfall does attract them. Artificial snow making is costly and requires infrastructure (ponds and electric lines) with very narrow range of weather conditions. Related companies are searching for alternatives and one of them can be "weather regulation" by distribution of some chemical components in clouds. It did not happen yet, but can happen soon. The consequences of such interference in Nature is hardly known. The ski tourism is not the

  19. Selected Topics in MicroNano-robotics for Biomedical Applications

    CERN Document Server

    2013-01-01

    Selected Topics in Micro/Nano-robotics for Biomedical Applications features a system approach and incorporates modern methodologies in autonomous mobile robots for programmable and controllable micro/nano-robots aiming at biomedical applications. The book provides chapters of instructional materials and cutting-edge research results in micro/nanorobotics for biomedical applications. The book presents new sensing technology on nanofibers, new power supply techniques including miniature fuel cells and energy harvesting devices, and manipulation techniques including AFM-based nano-robotic manipulation, robot-aided optical tweezers, and robot-assisted catheter surgery systems. It also contains case studies on using micro/nano-robots in biomedical environments and in biomedicine, as well as a design example to conceptually develop a Vitamin-pill sized robot to enter human’s gastrointestinal tract. Each chapter covers a different topic of the highly interdisciplinary area. Bring together the selected topics into ...

  20. Topical cyclosporine for atopic keratoconjunctivitis.

    Science.gov (United States)

    González-López, Julio J; López-Alcalde, Jesús; Morcillo Laiz, Rafael; Fernández Buenaga, Roberto; Rebolleda Fernández, Gema

    2012-09-12

    Atopic keratoconjunctivitis (AKC) is a chronic ocular surface non-infectious inflammatory condition that atopic dermatitis patients may suffer at any time point in the course of their dermatologic disease and is independent of its degree of severity. AKC is usually not self resolving and it poses a higher risk of corneal injuries and severe sequelae. Management of AKC should prevent or treat corneal damage. Although topical corticosteroids remain the standard treatment for patients with AKC, prolonged use may lead to complications. Topical cyclosporine A (CsA) may improve AKC signs and symptoms, and be used as a corticosteroid sparing agent. To determine the efficacy and gather evidence on safety from randomised controlled trials (RCTs) of topical CsA in patients with AKC. We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2012, Issue 6), MEDLINE (January 1946 to July 2012), EMBASE (January 1980 to July 2012), Latin American and Caribbean Literature on Health Sciences (LILACS) (January 1982 to July 2012), Cumulative Index to Nursing and Allied Health Literature (CINAHL) (January 1937 to July 2012), OpenGrey (System for Information on Grey Literature in Europe) (www.opengrey.eu/), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrials.gov), the WHO International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en), the IFPMA Clinical Trials Portal (http://clinicaltrials.ifpma.org/no_cache/en/myportal/index.htm) and Web of Science Conference Proceedings Citation Index- Science (CPCI-S). We did not use any date or language restrictions in the electronic searches for trials. The electronic databases were last searched on 9 July 2012. We also handsearched the following conference proceedings: American Academy of Ophthalmology, Association for Research in Vision and Ophthalmology, International Council of Opthalmology and Societas

  1. AMNT 2014. Key Topic: Reactor operation, safety - report. Pt. 1

    Energy Technology Data Exchange (ETDEWEB)

    Schaffrath, Andreas [Gesellschaft fuer Anlagen- und Reaktorsicherheit mbH (GRS), Garching (Germany). Forschungszentrum

    2014-10-15

    Summary report on one session of the Annual Conference on Nuclear Technology held in Frankfurt, 6 to 8 May 2014: - Safety of Nuclear Installations - Methods, Analysis, Results: Backfittings for the Improvement of Safety and Efficiency. The other Sessions of the Key Topics 'Reactor Operation, Safety', 'Competence, Innovation, Regulation' and 'Fuel, Decommissioning and Disposal' will be covered in further issues of atw.

  2. Topical antifungal agents: an update.

    Science.gov (United States)

    Diehl, K B

    1996-10-01

    So many topical antifungal agents have been introduced that it has become very difficult to select the proper agent for a given infection. Nonspecific agents have been available for many years, and they are still effective in many situations. These agents include Whitfield's ointment, Castellani paint, gentian violet, potassium permanganate, undecylenic acid and selenium sulfide. Specific antifungal agents include, among others, the polyenes (nystatin, amphotericin B), the imidazoles (metronidazole, clotrimazole) and the allylamines (terbinafine, naftifine). Although the choice of an antifungal agent should be based on an accurate diagnosis, many clinicians believe that topical miconazole is a relatively effective agent for the treatment of most mycotic infections. Terbinafine and other newer drugs have primary fungicidal effects. Compared with older antifungal agents, these newer drugs can be used in lower concentrations and shorter therapeutic courses. Studies are needed to evaluate the clinical efficacies and cost advantages of both newer and traditional agents.

  3. Topics in computational linear optimization

    DEFF Research Database (Denmark)

    Hultberg, Tim Helge

    2000-01-01

    Linear optimization has been an active area of research ever since the pioneering work of G. Dantzig more than 50 years ago. This research has produced a long sequence of practical as well as theoretical improvements of the solution techniques avilable for solving linear optimization problems...... of high quality solvers and the use of algebraic modelling systems to handle the communication between the modeller and the solver. This dissertation features four topics in computational linear optimization: A) automatic reformulation of mixed 0/1 linear programs, B) direct solution of sparse unsymmetric...... systems of linear equations, C) reduction of linear programs and D) integration of algebraic modelling of linear optimization problems in C++. Each of these topics is treated in a separate paper included in this dissertation. The efficiency of solving mixed 0-1 linear programs by linear programming based...

  4. Do scientists trace hot topics?

    Science.gov (United States)

    Wei, Tian; Li, Menghui; Wu, Chensheng; Yan, Xiao-Yong; Fan, Ying; Di, Zengru; Wu, Jinshan

    2013-01-01

    Do scientists follow hot topics in their scientific investigations? In this paper, by performing analysis to papers published in the American Physical Society (APS) Physical Review journals, it is found that papers are more likely to be attracted by hot fields, where the hotness of a field is measured by the number of papers belonging to the field. This indicates that scientists generally do follow hot topics. However, there are qualitative differences among scientists from various countries, among research works regarding different number of authors, different number of affiliations and different number of references. These observations could be valuable for policy makers when deciding research funding and also for individual researchers when searching for scientific projects.

  5. UMTRAP research on cover design for uranium mill tailings

    International Nuclear Information System (INIS)

    Rogers, V.C.; Nielson, K.K.

    1984-01-01

    As a result of the UMTRAP research on radon attenuation and tailings cover design, the basis and general procedures are available for designing covers for uranium tailings piles to meet present criteria for radon emissions. The general procedures involve assessment of the radon source strength of the tailings, definition of candidate cover materials, assessment of their moisture retention and radon diffusion properties, computing the required thicknesses of these materials, comparing costs, and evaluating long-term performance criteria. Final selection of the cover design must assure adequate long-term performance and radon retention as first priority, and keep costs to a minimum in achieving this goal

  6. Recent topics in nonlinear PDE

    International Nuclear Information System (INIS)

    Mimura, Masayasu; Nishida, Takaaki

    1984-01-01

    The meeting on the subject of nonlinear partial differential equations was held at Hiroshima University in February, 1983. Leading and active mathematicians were invited to talk on their current research interests in nonlinear pdes occuring in the areas of fluid dynamics, free boundary problems, population dynamics and mathematical physics. This volume contains the theory of nonlinear pdes and the related topics which have been recently developed in Japan. (Auth.)

  7. Probabilistic analysis and related topics

    CERN Document Server

    Bharucha-Reid, A T

    1983-01-01

    Probabilistic Analysis and Related Topics, Volume 3 focuses on the continuity, integrability, and differentiability of random functions, including operator theory, measure theory, and functional and numerical analysis. The selection first offers information on the qualitative theory of stochastic systems and Langevin equations with multiplicative noise. Discussions focus on phase-space evolution via direct integration, phase-space evolution, linear and nonlinear systems, linearization, and generalizations. The text then ponders on the stability theory of stochastic difference systems and Marko

  8. Topics in clinical oncology. 15

    International Nuclear Information System (INIS)

    Cepcek, P.

    1987-12-01

    The monograph comprising primarily papers on topical subjects of oncology and cancer research, contains also a selection of papers presented at the 2. Congress of the Czechoslovak Society of Nuclear Medicine and Radiation Hygiene. Seven papers were selected on behalf of their subject related to clinical oncology. All of them were iputted in INIS; five of them deal with the scintiscanning of the skeleton of cancer patients, one with radioimmunodetection of tumors, and one with radionuclide lymphography. (A.K.)

  9. Probabilistic analysis and related topics

    CERN Document Server

    Bharucha-Reid, A T

    1979-01-01

    Probabilistic Analysis and Related Topics, Volume 2 focuses on the integrability, continuity, and differentiability of random functions, as well as functional analysis, measure theory, operator theory, and numerical analysis.The selection first offers information on the optimal control of stochastic systems and Gleason measures. Discussions focus on convergence of Gleason measures, random Gleason measures, orthogonally scattered Gleason measures, existence of optimal controls without feedback, random necessary conditions, and Gleason measures in tensor products. The text then elaborates on an

  10. Stochastic Analysis and Related Topics

    CERN Document Server

    Ustunel, Ali

    1988-01-01

    The Silvri Workshop was divided into a short summer school and a working conference, producing lectures and research papers on recent developments in stochastic analysis on Wiener space. The topics treated in the lectures relate to the Malliavin calculus, the Skorohod integral and nonlinear functionals of white noise. Most of the research papers are applications of these subjects. This volume addresses researchers and graduate students in stochastic processes and theoretical physics.

  11. Using a Vaccine Proposal Assignment to Help Students Synthesize Topics Covered in an Undergraduate Immunology Course

    Directory of Open Access Journals (Sweden)

    Rebecca L. Sparks-Thissen

    2015-08-01

    Full Text Available Undergraduate students often have difficulty keeping track of all the pieces of the immune response and how they relate to each other.  To help students synthesize the information in an upper-level, undergraduate immunology course, the students in my course investigate the immune response to pathogen of their choosing and then use that information to design a vaccine to that pathogen.

  12. Destination reputation in online media: Covered topics and perceived online dominant opinion

    OpenAIRE

    Marchiori, Elena; Cantoni, Lorenzo

    2013-01-01

    Context: Online public opinions using various forms of social media are generating challenges for the tourism industry, which is intrinsically a “reputation-dependent” domain. Electronic-word-of-mouth (eWOM) has forced destination managers to rethink branding strategies, suggesting a shift from an architecture brand perspective to a live context perspective where travel markets are considered to be conversations and the monitoring of online conversations constitutes the first phase of ...

  13. Topical antifungals for seborrhoeic dermatitis

    Science.gov (United States)

    Okokon, Enembe O; Verbeek, Jos H; Ruotsalainen, Jani H; Ojo, Olumuyiwa A; Bakhoya, Victor Nyange

    2015-01-01

    ), two bifonazole trials (N = 136) and one clotrimazole trial (N = 126) that compared the effectiveness of these treatments versus placebo or vehicle. Nine ketoconazole trials (N = 632) and one miconazole trial (N = 47) compared these treatments versus steroids. Fourteen studies (N = 1541) compared one antifungal versus another or compared different doses or schedules of administration of the same agent versus one another. Ketoconazole Topical ketoconazole 2% treatment showed a 31% lower risk of failed clearance of rashes compared with placebo (risk ratio (RR) 0.69, 95% confidence interval (CI) 0.59 to 0.81, eight studies, low-quality evidence) at four weeks of follow-up, but the effect on side effects was uncertain because evidence was of very low quality (RR 0.97, 95% CI 0.58 to 1.64, six studies); heterogeneity between studies was substantial (I² = 74%). The median proportion of those who did not have clearance in the placebo groups was 69%. Ketoconazole treatment resulted in a remission rate similar to that of steroids (RR 1.17, 95% CI 0.95 to 1.44, six studies, low-quality evidence), but occurrence of side effects was 44% lower in the ketoconazole group than in the steroid group (RR 0.56, 95% CI 0.32 to 0.96, eight studies, moderate-quality evidence). Ketoconozale yielded a similar remission failure rate as ciclopirox (RR 1.09, 95% CI 0.95 to 1.26, three studies, low-quality evidence). Most comparisons between ketoconazole and other antifungals were based on single studies that showed comparability of treatment effects. Ciclopirox Ciclopirox 1% led to a lower failed remission rate than placebo at four weeks of follow-up (RR 0.79, 95% CI 0.67 to 0.94, eight studies, moderate-quality evidence) with similar rates of side effects (RR 0.9, 95% CI 0.72 to 1.11, four studies, moderate-quality evidence). Other antifungals Clotrimazole and miconazole efficacies were comparable with those of steroids on short-term assessment in single studies. Treatment effects on individual

  14. Retrospective Evaluation of Topical Bimatoprost and Iris Pigmentation Change.

    Science.gov (United States)

    Zaleski-Larsen, Lisa A; Ruth, Nadine H; Fabi, Sabrina G

    2017-12-01

    Topical bimatoprost is a topical prostaglandin analog originally used to treat glaucoma and more recently used to cosmetically induce hypertrichosis of the eyelashes. Iris pigmentation change has been noted in the treatment of glaucoma but has not been assessed with the cosmetic periorbital application of bimatoprost. To evaluate for iris pigmentation change with the long-term cosmetic use of topical bimatoprost. A retrospective chart review in a cosmetic dermatology practice of women (N = 50) who consistently purchased topical bimatoprost over an average of 4.59 years was compared with that of age-matched non-bimatoprost patients (N = 50). A blinded evaluator assessed each patient for iris pigmentary change. No iris pigmentation change was noted with the cutaneous application of bimatoprost. The cutaneous application of bimatoprost appears to be safe with minimal risk for iris pigmentation change.

  15. Selected topics in image science

    International Nuclear Information System (INIS)

    Nalcioglu, O.; Cho, Z.H.

    1984-01-01

    A review of the state of the art in diagnostic imaging via computers. Applications covered include emission tomography, digital radiography, and ultrasound and nuclear magnetic resonance imaging. Contents, abridged: Direct Fourier reconstruction techniques. Radiation detectors for CT instrumentation. Single photon emission computed tomography: potentials and limitations. Matched filtering for digital subtraction angiography

  16. Link-topic model for biomedical abbreviation disambiguation.

    Science.gov (United States)

    Kim, Seonho; Yoon, Juntae

    2015-02-01

    The ambiguity of biomedical abbreviations is one of the challenges in biomedical text mining systems. In particular, the handling of term variants and abbreviations without nearby definitions is a critical issue. In this study, we adopt the concepts of topic of document and word link to disambiguate biomedical abbreviations. We newly suggest the link topic model inspired by the latent Dirichlet allocation model, in which each document is perceived as a random mixture of topics, where each topic is characterized by a distribution over words. Thus, the most probable expansions with respect to abbreviations of a given abstract are determined by word-topic, document-topic, and word-link distributions estimated from a document collection through the link topic model. The model allows two distinct modes of word generation to incorporate semantic dependencies among words, particularly long form words of abbreviations and their sentential co-occurring words; a word can be generated either dependently on the long form of the abbreviation or independently. The semantic dependency between two words is defined as a link and a new random parameter for the link is assigned to each word as well as a topic parameter. Because the link status indicates whether the word constitutes a link with a given specific long form, it has the effect of determining whether a word forms a unigram or a skipping/consecutive bigram with respect to the long form. Furthermore, we place a constraint on the model so that a word has the same topic as a specific long form if it is generated in reference to the long form. Consequently, documents are generated from the two hidden parameters, i.e. topic and link, and the most probable expansion of a specific abbreviation is estimated from the parameters. Our model relaxes the bag-of-words assumption of the standard topic model in which the word order is neglected, and it captures a richer structure of text than does the standard topic model by considering

  17. Results of the 2010 IGSC Topical Session on Optimisation

    International Nuclear Information System (INIS)

    Bailey, Lucy

    2014-01-01

    Document available in abstract form only. Full text follows: The 2010 IGSC topical session on optimisation explored a wide range of issues concerning optimisation throughout the radioactive waste management process. Philosophical and ethical questions were discussed, such as: - To what extent is the process of optimisation more important than the end result? - How do we balance long-term environmental safety with near-term operational safety? - For how long should options be kept open? - In balancing safety and excessive cost, when is BAT achieved and who decides on this? * How should we balance the needs of current society with those of future generations? It was clear that optimisation is about getting the right balance between a range of issues that cover: radiation protection, environmental protection, operational safety, operational requirements, social expectations and cost. The optimisation process will also need to respect various constraints, which are likely to include: regulatory requirements, site restrictions, community-imposed requirements or restrictions and resource constraints. These issues were explored through a number of presentations that discussed practical cases of optimisation occurring at different stages of international radioactive waste management programmes. These covered: - Operations and decommissioning - management of large disused components, from the findings of an international study, presented by WPDD; - Concept option selection, prior to site selection - upstream and disposal system optioneering in the UK; - Siting decisions - examples from both Germany and France, explaining how optimisation is being used to support site comparisons and communicate siting decisions; - Repository design decisions - comparison of KBS-3 horizontal and vertical deposition options in Finland; and - On-going optimisation during repository operation - operational experience from WIPP in the US. The variety of the remarks and views expressed during the

  18. COVERS Neonatal Pain Scale: Development and Validation

    Directory of Open Access Journals (Sweden)

    Ivan L. Hand

    2010-01-01

    Full Text Available Newborns and infants are often exposed to painful procedures during hospitalization. Several different scales have been validated to assess pain in specific populations of pediatric patients, but no single scale can easily and accurately assess pain in all newborns and infants regardless of gestational age and disease state. A new pain scale was developed, the COVERS scale, which incorporates 6 physiological and behavioral measures for scoring. Newborns admitted to the Neonatal Intensive Care Unit or Well Baby Nursery were evaluated for pain/discomfort during two procedures, a heel prick and a diaper change. Pain was assessed using indicators from three previously established scales (CRIES, the Premature Infant Pain Profile, and the Neonatal Infant Pain Scale, as well as the COVERS Scale, depending upon gestational age. Premature infant testing resulted in similar pain assessments using the COVERS and PIPP scales with an r=0.84. For the full-term infants, the COVERS scale and NIPS scale resulted in similar pain assessments with an r=0.95. The COVERS scale is a valid pain scale that can be used in the clinical setting to assess pain in newborns and infants and is universally applicable to all neonates, regardless of their age or physiological state.

  19. Inhibition of Corneal Neovascularization by Topical and Subconjunctival Tigecycline

    Directory of Open Access Journals (Sweden)

    Sertan Goktas

    2014-01-01

    Full Text Available Objective. To investigate the effects of topical and subconjunctival tigecycline on the prevention of corneal neovascularization. Materials and Methods. Following chemical burn, thirty-two rats were treated daily with topical instillation of 1 mg/mL tigecycline (group 1 or subconjunctival instillation of 1 mg/mL tigecycline (group 3 for 7 days. Control rats received topical (group 2 or subconjunctival (group 4 0.9% saline. Digital photographs of the cornea were taken on the eighth day after treatment and analyzed to determine the percentage area of the cornea covered by neovascularization. Corneal sections were analyzed histopathologically. Results. The median percentages of corneal neovascularization in groups 1 and 3 were 48% (95% confidence interval (CI, 44.2–55.8% and 33.5% (95% CI, 26.6–39.2%, respectively. The median percentages of corneal neovascularization of groups 1 and 3 were significantly lower than that of the control group (P=0.03 and P<0.001, resp.. Histologic examination of samples from groups 1 and 3 showed lower vascularity than that of control groups. Conclusion. Topical and subconjunctival administration of tigecycline seems to be showing promising therapeutic effects on the prevention of corneal neovascularization. Furthermore, subconjunctival administration of tigecycline is more potent than topical administration in the inhibition of corneal neovascularization.

  20. Combinatorial aspects of covering arrays

    Directory of Open Access Journals (Sweden)

    Charles J. Colbourn

    2004-11-01

    Full Text Available Covering arrays generalize orthogonal arrays by requiring that t -tuples be covered, but not requiring that the appearance of t -tuples be balanced.Their uses in screening experiments has found application in software testing, hardware testing, and a variety of fields in which interactions among factors are to be identified. Here a combinatorial view of covering arrays is adopted, encompassing basic bounds, direct constructions, recursive constructions, algorithmic methods, and applications.

  1. Tactile friction of topical formulations.

    Science.gov (United States)

    Skedung, L; Buraczewska-Norin, I; Dawood, N; Rutland, M W; Ringstad, L

    2016-02-01

    The tactile perception is essential for all types of topical formulations (cosmetic, pharmaceutical, medical device) and the possibility to predict the sensorial response by using instrumental methods instead of sensory testing would save time and cost at an early stage product development. Here, we report on an instrumental evaluation method using tactile friction measurements to estimate perceptual attributes of topical formulations. Friction was measured between an index finger and an artificial skin substrate after application of formulations using a force sensor. Both model formulations of liquid crystalline phase structures with significantly different tactile properties, as well as commercial pharmaceutical moisturizing creams being more tactile-similar, were investigated. Friction coefficients were calculated as the ratio of the friction force to the applied load. The structures of the model formulations and phase transitions as a result of water evaporation were identified using optical microscopy. The friction device could distinguish friction coefficients between the phase structures, as well as the commercial creams after spreading and absorption into the substrate. In addition, phase transitions resulting in alterations in the feel of the formulations could be detected. A correlation was established between skin hydration and friction coefficient, where hydrated skin gave rise to higher friction. Also a link between skin smoothening and finger friction was established for the commercial moisturizing creams, although further investigations are needed to analyse this and correlations with other sensorial attributes in more detail. The present investigation shows that tactile friction measurements have potential as an alternative or complement in the evaluation of perception of topical formulations. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. Topic extraction from adverbial clauses

    Directory of Open Access Journals (Sweden)

    Carlos Rubio Alcalá

    2016-06-01

    Full Text Available This paper offers new data to support findings about Topic extraction from adverbial clauses. Since such clauses are strong islands, they should not allow extraction of any kind, but we show here that if the appropriate conditions are met, Topics of the CLLD kind in Romance can move out of them. We propose that two conditions must be met for such movement to be possible: the first is that the adverbial clause must have undergone topicalisation in the first place; the second is that the adverbial clause is inherently topical from a semantic viewpoint. Contrast with other language families (Germanic, Quechua and Japanese is provided and the semantic implications of the proposal are briefly discussed. Keywords: topicalisation; Clitic Left Dislocation; syntactic islands; adverbial clauses Este artículo ofrece nuevos datos sobre la extracción de Tópicos desde oraciones subordinadas adverbiales. Dado que dichas oraciones son islas fuertes, no deberían permitir extracción de ningún tipo, pero mostramos que si se dan las condiciones apropiadas, los Tópicos del tipo CLLD en lenguas románicas pueden desplazarse fuera de ellas. Proponemos que se deben cumplir dos condiciones para que ese movimiento sea posible: la primera es que la propia subordinada adverbial se haya topicalizado en primer lugar; la segunda es que la subordinada adverbial sea inherentemente un Tópico desde el punto de vista semántico. Proporcionamos también algunos contrastes con otras familias lingüísticas (germánica, quechua y japonés y se discuten brevemente las implicaciones semánticas de la propuesta. Palabras clave: topicalización; dislocación a la izquierda con clítico; islas sintácticas; oraciones adverbiales

  3. GLCF: Landsat GeoCover

    Science.gov (United States)

    satellite imagery provided in a standardized, orthorectified format, covering the entire land surface of the * Orthorectification * Distribution Status * Hard Media Orders * Letters Delivered Quick Links * Create True Color

  4. Topics in deep inelastic scattering

    International Nuclear Information System (INIS)

    Wandzura, S.M.

    1977-01-01

    Several topics in deep inelastic lepton--nucleon scattering are discussed, with emphasis on the structure functions appearing in polarized experiments. The major results are: infinite set of new sum rules reducing the number of independent spin dependent structure functions (for electroproduction) from two to one; the application of the techniques of Nachtmann to extract the coefficients appearing in the Wilson operator product expansion; and radiative corrections to the Wilson coefficients of free field theory. Also discussed are the use of dimensional regularization to simplify the calculation of these radiative corrections

  5. Topics in conformal field theory

    International Nuclear Information System (INIS)

    Kiritsis, E.B.

    1988-01-01

    In this work two major topics in Conformal Field Theory are discussed. First a detailed investigation of N = 2 Superconformal theories is presented. The structure of the representations of the N = 2 superconformal algebras is investigated and the character formulae are calculated. The general structure of N = 2 superconformal theories is elucidated and the operator algebra of the minimal models is derived. The first minimal system is discussed in more detail. Second, applications of the conformal techniques are studied in the Ashkin-Teller model. The c = 1 as well as the c = 1/2 critical lines are discussed in detail

  6. Topics in atomic collision theory

    CERN Document Server

    Geltman, Sydney; Brueckner, Keith A

    1969-01-01

    Topics in Atomic Collision Theory originated in a course of graduate lectures given at the University of Colorado and at University College in London. It is recommended for students in physics and related fields who are interested in the application of quantum scattering theory to low-energy atomic collision phenomena. No attention is given to the electromagnetic, nuclear, or elementary particle domains. The book is organized into three parts: static field scattering, electron-atom collisions, and atom-atom collisions. These are in the order of increasing physical complexity and hence necessar

  7. Topics on Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Directorate (NVE). To prevent cross-subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. Chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently coordinate the

  8. Topics in Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Directorate (NVE). To prevent cross-subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. To start with, chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently

  9. Topics on Electricity Transmission Pricing

    International Nuclear Information System (INIS)

    Bjoerndal, Mette

    2000-02-01

    -subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. To start with, chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently coordinate the allocation of transmission

  10. #Healthy Selfies: Exploration of Health Topics on Instagram.

    Science.gov (United States)

    Muralidhara, Sachin; Paul, Michael J

    2018-06-29

    Social media provides a complementary source of information for public health surveillance. The dominate data source for this type of monitoring is the microblogging platform Twitter, which is convenient due to the free availability of public data. Less is known about the utility of other social media platforms, despite their popularity. This work aims to characterize the health topics that are prominently discussed in the image-sharing platform Instagram, as a step toward understanding how this data might be used for public health research. The study uses a topic modeling approach to discover topics in a dataset of 96,426 Instagram posts containing hashtags related to health. We use a polylingual topic model, initially developed for datasets in different natural languages, to model different modalities of data: hashtags, caption words, and image tags automatically extracted using a computer vision tool. We identified 47 health-related topics in the data (kappa=.77), covering ten broad categories: acute illness, alternative medicine, chronic illness and pain, diet, exercise, health care & medicine, mental health, musculoskeletal health and dermatology, sleep, and substance use. The most prevalent topics were related to diet (8,293/96,426; 8.6% of posts) and exercise (7,328/96,426; 7.6% of posts). A large and diverse set of health topics are discussed in Instagram. The extracted image tags were generally too coarse and noisy to be used for identifying posts but were in some cases accurate for identifying images relevant to studying diet and substance use. Instagram shows potential as a source of public health information, though limitations in data collection and metadata availability may limit its use in comparison to platforms like Twitter. ©Sachin Muralidhara, Michael J. Paul. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 29.06.2018.

  11. Theoretical topics in B-physics

    International Nuclear Information System (INIS)

    Bjorken, J.D.

    1990-12-01

    The bottom quark should need no introduction. Other than the undiscovered top quark, it is by far the most fashionable of the six. There is good reason for this. It is bottom-quark behavior which holds out the most hope of measuring and understanding some of the most hope of measuring and understanding some of the most fundamental and delicate parameters of the standard model -- those having to do with the origin of electroweak mixing -- and thereby in all probability also the origin of quark mass. Also interwoven into this is the subject of CP violation, and its proposed interpretation in terms of electroweak mixing. In this section we shall review the basics of electroweak mixing and how it is impacted by the study of b-quark properties. There are by now many lecture series and workshop proceedings devoted to this topic, so I will not try to be comprehensive, but only hit some highlights. 28 refs., 14 figs., 4 tabs

  12. Precession electron diffraction – a topical review

    Directory of Open Access Journals (Sweden)

    Paul A. Midgley

    2015-01-01

    Full Text Available In the 20 years since precession electron diffraction (PED was introduced, it has grown from a little-known niche technique to one that is seen as a cornerstone of electron crystallography. It is now used primarily in two ways. The first is to determine crystal structures, to identify lattice parameters and symmetry, and ultimately to solve the atomic structure ab initio. The second is, through connection with the microscope scanning system, to map the local orientation of the specimen to investigate crystal texture, rotation and strain at the nanometre scale. This topical review brings the reader up to date, highlighting recent successes using PED and providing some pointers to the future in terms of method development and how the technique can meet some of the needs of the X-ray crystallography community. Complementary electron techniques are also discussed, together with how a synergy of methods may provide the best approach to electron-based structure analysis.

  13. Percolation, SLE and related topics

    CERN Document Server

    Kreimer, Dirk; Renormalization and universality in mathematical physics

    2007-01-01

    This book covers a wide range of phenomena in the natural sciences dominated by notions of universality and renormalization. The contributions in this volume are equally broad in their approach to these phenomena, offering the mathematical as well as the perspective of the applied sciences. They explore renormalization theory in quantum field theory and statistical physics, and its connections to modern mathematics as well as physics on scales from the microscopic to the macroscopic.

  14. Topical, geospatial, and temporal diffusion of the 2015 North American Menopause Society position statement on nonhormonal management of vasomotor symptoms.

    Science.gov (United States)

    Carpenter, Janet S; Laine, Tei; Harrison, Blake; LePage, Meghan; Pierce, Taran; Hoteling, Nathan; Börner, Katy

    2017-10-01

    We sought to depict the topical, geospatial, and temporal diffusion of the 2015 North American Menopause Society position statement on the nonhormonal management of menopause-associated vasomotor symptoms released on September 21, 2015, and its associated press release from September 23, 2015. Three data sources were used: online news articles, National Public Radio, and Twitter. For topical diffusion, we compared keywords and their frequencies among the position statement, press release, and online news articles. We also created a network figure depicting relationships across key content categories or nodes. For geospatial diffusion within the United States, we compared locations of the 109 National Public Radio (NPR) stations covering the statement to 775 NPR stations not covering the statement. For temporal diffusion, we normalized and segmented Twitter data into periods before and after the press release (September 12, 2015 to September 22, 2015 vs September 23, 2015 to October 3, 2015) and conducted a burst analysis to identify changes in tweets from before to after. Topical information diffused across sources was similar with the exception of the more scientific terms "vasomotor symptoms" or "vms" versus the more colloquial term "hot flashes." Online news articles indicated media coverage of the statement was mainly concentrated in the United States. NPR station data showed similar proportions of stations airing the story across the four census regions (Northeast, Midwest, south, west; P = 0.649). Release of the statement coincided with bursts in the menopause conversation on Twitter. The findings of this study may be useful for directing the development and dissemination of future North American Menopause Society position statements and/or press releases.

  15. Theoretical topics in particle physics

    International Nuclear Information System (INIS)

    Roberts, L.A.

    1986-01-01

    This dissertation contains three parts, each with a distinct topic. The three topics are (1) Higgs-boson decays at the superconducting supercollider, (2) radiative corrections to the decay π 0 → γe + e - and (3) generalized random paths in three and four dimensions. In part I, distributions in cos(theta)/sub lab/, rapidity, energy, and p/sub T/ for the intermediate vector bosons resulting from p + p → (H 0 → W + W - , Z 0 Z 0 ) + X and p + p → (W + W - , W + Z 0 + W - Z 0 ,Z 0 Z 0 ) + X at √s = 40 TeV are compared for Higgs-boson masses of 5m/sub w/ and 7m/sub w/. The Higgs-boson-decay signal should be visible in the energy and p/sub T/ distributions of the vector bosons. In Part II, the radiative corrections to both the decay rate for π 0 → γe + e - and the differential spectrum in the invariant mass of the Dalitz pain for experiments with limited geometrical acceptance are calculated. In Part III, the author introduces a generalized model for random paths (in arbitrary dimension) which smoothly interpolates between the standard paths (fermionic or bosonic) and the self-avoiding paths. An efficient Monte Carlo algorithm to simulate the model is presented along with some preliminary results for the average length, intersection, overlap and mean square size of paths in three and four dimensions

  16. InfoPoems: Various Topics | | South African Family Practice

    African Journals Online (AJOL)

    Topics: 1.Medications help passage of kidney stones. 2.Limited data on probiotics to prevent antibiotic induced diarrhea in kids. 3.Best way to perform lumbar puncture and analyze results. 4.Acupuncture effective for long-term back pain relief. InfoPOEMs® keep you current and answers your clinical medicine questions at ...

  17. Topicality and Complexity in the Acquisition of Norwegian Object Shift

    Science.gov (United States)

    Anderssen, Merete; Bentzen, Kristine; Rodina, Yulia

    2012-01-01

    This article investigates the acquisition of object shift in Norwegian child language. We show that object shift is complex derivationally, distributionally, and referentially, and propose a new analysis in terms of IP-internal topicalization. The results of an elicited production study with 27 monolingual Norwegian-speaking children (ages…

  18. Climate Impacts of Cover Crops

    Science.gov (United States)

    Lombardozzi, D.; Wieder, W. R.; Bonan, G. B.; Morris, C. K.; Grandy, S.

    2016-12-01

    Cover crops are planted in agricultural rotation with the intention of protecting soil rather than harvest. Cover crops have numerous environmental benefits that include preventing soil erosion, increasing soil fertility, and providing weed and pest control- among others. In addition to localized environmental benefits, cover crops can have important regional or global biogeochemical impacts by increasing soil organic carbon, changing emissions of greenhouse trace gases like nitrous oxide and methane, and reducing hydrologic nitrogen losses. Cover crops may additionally affect climate by changing biogeophysical processes, like albedo and latent heat flux, though these potential changes have not yet been evaluated. Here we use the coupled Community Atmosphere Model (CAM5) - Community Land Model (CLM4.5) to test how planting cover crops in the United States may change biogeophysical fluxes and climate. We present seasonal changes in albedo, heat fluxes, evaporative partitioning, radiation, and the resulting changes in temperature. Preliminary analyses show that during seasons when cover crops are planted, latent heat flux increases and albedo decreases, changing the evaporative fraction and surface temperatures. Understanding both the biogeophysical changes caused by planting cover crops in this study and the biogeochemical changes found in other studies will give a clearer picture of the overall impacts of cover crops on climate and atmospheric chemistry, informing how this land use strategy will impact climate in the future.

  19. Landfill covers for dry environments

    International Nuclear Information System (INIS)

    Dwyer, S.F.

    1996-01-01

    A large-scale landfill cover field test is currently underway at Sandia National Laboratories in Albuquerque, New Mexico. It is intended to compare and document the performance of alternative landfill cover technologies of various costs and complexities for interim stabilization and/or final closure of landfills in arid and semi-arid environments. Test plots of traditional designs recommended by the US Environmental Protection Agency for both RCRA Subtitle open-quote C close-quote and open-quote D close-quote regulated facilities have been constructed side-by-side with the alternative covers and will serve as baselines for comparison to these alternative covers. The alternative covers were designed specifically for dry environments. The covers will be tested under both ambient and stressed conditions. All covers have been instrumented to measure water balance variables and soil temperature. An on-site weather station records all pertinent climatological data. A key to acceptance of an alternative environmental technology is seeking regulatory acceptance and eventual permitting. The lack of acceptance by regulatory agencies is a significant barrier to development and implementation of innovative cover technologies. Much of the effort on this demonstration has been toward gaining regulatory and public acceptance

  20. Automatic design of magazine covers

    Science.gov (United States)

    Jahanian, Ali; Liu, Jerry; Tretter, Daniel R.; Lin, Qian; Damera-Venkata, Niranjan; O'Brien-Strain, Eamonn; Lee, Seungyon; Fan, Jian; Allebach, Jan P.

    2012-03-01

    In this paper, we propose a system for automatic design of magazine covers that quantifies a number of concepts from art and aesthetics. Our solution to automatic design of this type of media has been shaped by input from professional designers, magazine art directors and editorial boards, and journalists. Consequently, a number of principles in design and rules in designing magazine covers are delineated. Several techniques are derived and employed in order to quantify and implement these principles and rules in the format of a software framework. At this stage, our framework divides the task of design into three main modules: layout of magazine cover elements, choice of color for masthead and cover lines, and typography of cover lines. Feedback from professional designers on our designs suggests that our results are congruent with their intuition.

  1. Topical ganciclovir in the treatment of acute herpetic keratitis.

    Science.gov (United States)

    Tabbara, Khalid F; Al Balushi, Noorjehan

    2010-08-19

    Herpetic keratitis is caused by herpes simplex virus (HSV) and is a common cause of corneal blindness. Following a primary ocular herpetic infection, latency of the virus occurs, followed by subsequent recurrences of herpetic keratitis. Such recurrences may lead to structural damage of the cornea. Recurrent herpetic keratitis is a common indication for corneal transplantation. Recurrences of herpetic keratitis in the corneal graft may lead to corneal graft rejection. Several antiviral agents for HSV are available, including the thymidine analogs. Prolonged use of thymidine analogs may lead to toxicity of the ocular surface, including epithelial keratitis, corneal ulcers, follicular conjunctivitis, and punctal occlusions. Availability of topical antiviral agents that are safe and effective in the treatment and prophylaxis of herpetic keratitis is highly desirable. Ganciclovir is a potent inhibitor of members of the herpes virus family. The drug has been used systemically for the treatment of cytomegalovirus (CMV) retinitis. Its hematologic toxicity secondary to systemic administration led to its limited use in herpetic infections. On the other hand, topical ganciclovir has been shown to be as safe and effective as acyclovir in the treatment of herpetic epithelial keratitis. Furthermore, topical ganciclovir can reach therapeutic levels in the cornea and aqueous humor following topical application. Several clinical trials have shown that topical ganciclovir 0.15% ophthalmic gel is safe and effective in the treatment and prophylaxis of herpetic epithelial disease. Long-term use of ganciclovir ophthalmic gel in patients with penetrating keratoplasty following herpetic keratitis has prevented recurrences of the disease. Topical ganciclovir ophthalmic gel is well tolerated, does not cause toxic effects on the ocular surface, and does not cause hematologic abnormalities. Clinical studies have underscored the potential role of ganciclovir ophthalmic gel in the treatment and

  2. Topics in Banach space theory

    CERN Document Server

    Albiac, Fernando

    2016-01-01

    This text provides the reader with the necessary technical tools and background to reach the frontiers of research without the introduction of too many extraneous concepts. Detailed and accessible proofs are included, as are a variety of exercises and problems. The two new chapters in this second edition are devoted to two topics of much current interest amongst functional analysts: Greedy approximation with respect to bases in Banach spaces and nonlinear geometry of Banach spaces. This new material is intended to present these two directions of research for their intrinsic importance within Banach space theory, and to motivate graduate students interested in learning more about them. This textbook assumes only a basic knowledge of functional analysis, giving the reader a self-contained overview of the ideas and techniques in the development of modern Banach space theory. Special emphasis is placed on the study of the classical Lebesgue spaces Lp (and their sequence space analogues) and spaces of continuous f...

  3. Synergetics introduction and advanced topics

    CERN Document Server

    Haken, Hermann

    2004-01-01

    This book is an often-requested reprint of two classic texts by H. Haken: "Synergetics. An Introduction" and "Advanced Synergetics". Synergetics, an interdisciplinary research program initiated by H. Haken in 1969, deals with the systematic and methodological approach to the rapidly growing field of complexity. Going well beyond qualitative analogies between complex systems in fields as diverse as physics, chemistry, biology, sociology and economics, Synergetics uses tools from theoretical physics and mathematics to construct an unifying framework within which quantitative descriptions of complex, self-organizing systems can be made. This may well explain the timelessness of H. Haken's original texts on this topic, which are now recognized as landmarks in the field of complex systems. They provide both the beginning graduate student and the seasoned researcher with solid knowledge of the basic concepts and mathematical tools. Moreover, they admirably convey the spirit of the pioneering work by the founder of ...

  4. Topics in b-physics

    International Nuclear Information System (INIS)

    Bjorken, J.D.

    1988-09-01

    We discuss a few issues in the burgeoning field of physics of hadrons containing the b-quark. These include: A simple parameterization of the Kobayashi-Maskawa matrix featuring a triangle in the complex plane, a review of B/sub s/ and B/sub d/ mixing with special attention given to width-mixing and the CP-violating same-sign dilepton asymmetry, a discussion of the CP-violating decay B/sub d/ → /psi/π + π/sup /minus//, and a discussion of Cp-violating rate asymmetries in the two-body decays Λ/sub b/ → pπ/sup /minus// and Λ/sub b/ → pK/sup /minus//. The concluding discussion concerns generalizations beyond these specific topics. 22 refs., 6 figs

  5. Antibiotic Resistance: MedlinePlus Health Topic

    Science.gov (United States)

    ... GO GO About MedlinePlus Site Map FAQs Customer Support Health Topics Drugs & Supplements Videos & Tools Español You Are Here: Home → Health Topics → Antibiotic Resistance URL of this page: https://medlineplus.gov/antibioticresistance. ...

  6. Topical Antibacterials and Global Challenges on Resistance ...

    African Journals Online (AJOL)

    skin infections can be easily treated with topical antibacterial medication that is available over the counter or by ... infection in minor cut or burn, eyes and ear infection [5]. .... Sensitive/dry skin ... includes both oral and topical antibiotics, but.

  7. Eosinophilic Esophagitis: MedlinePlus Health Topic

    Science.gov (United States)

    ... Esophagitis (EoE) (American Academy of Allergy, Asthma, and Immunology) Also in Spanish Latest News Eosinophilic Esophagitis May ... Pediatric and Adolescent Patients (American College of Gastroenterology) Topic Image Related Health Topics Eosinophilic Disorders Esophagus Disorders ...

  8. Female Infertility: MedlinePlus Health Topic

    Science.gov (United States)

    ... Prolactin blood test (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Female Infertility updates ... Serum progesterone Show More Show Less Related Health Topics Assisted Reproductive Technology Infertility Male Infertility National Institutes ...

  9. Mobility Aids: MedlinePlus Health Topic

    Science.gov (United States)

    ... Mobility Problems (AGS Foundation for Health in Aging) Topic Image MedlinePlus Email Updates Get Mobility Aids updates ... standing and walking Using a cane Related Health Topics Assistive Devices Other Languages Find health information in ...

  10. Genetic Testing: MedlinePlus Health Topic

    Science.gov (United States)

    ... Your Family's Health (National Institutes of Health) - PDF Topic Image MedlinePlus Email Updates Get Genetic Testing updates ... testing and your cancer risk Karyotyping Related Health Topics Birth Defects Genetic Counseling Genetic Disorders Newborn Screening ...

  11. Folic Acid: MedlinePlus Health Topic

    Science.gov (United States)

    ... acid in diet (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Folic Acid updates ... acid - test Folic acid in diet Related Health Topics Vitamins National Institutes of Health The primary NIH ...

  12. Pneumococcal Infections: MedlinePlus Health Topic

    Science.gov (United States)

    ... Prevention, Immunization Action Coalition) - PDF Also in Spanish Topic Image MedlinePlus Email Updates Get Pneumococcal Infections updates ... ray Meningitis - pneumococcal Sputum gram stain Related Health Topics Meningitis Pneumonia Sepsis Sinusitis Streptococcal Infections National Institutes ...

  13. Chiropractic: MedlinePlus Health Topic

    Science.gov (United States)

    ... for back pain (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Chiropractic updates by ... ENCYCLOPEDIA Chiropractic care for back pain Related Health Topics Back Pain Complementary and Integrative Medicine National Institutes ...

  14. Wilms' Tumor: MedlinePlus Health Topic

    Science.gov (United States)

    ... Spanish Wilms tumor (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Wilms Tumor updates ... ENCYCLOPEDIA After chemotherapy - discharge Wilms tumor Related Health Topics Kidney Cancer National Institutes of Health The primary ...

  15. Child Safety: MedlinePlus Health Topic

    Science.gov (United States)

    ... injuries in children (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Child Safety updates ... safety Preventing head injuries in children Related Health Topics Infant and Newborn Care Internet Safety Motor Vehicle ...

  16. Diets: MedlinePlus Health Topic

    Science.gov (United States)

    ... Spanish Mediterranean diet (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Diets updates by ... foods Diet-busting foods Mediterranean diet Related Health Topics Child Nutrition DASH Eating Plan Diabetic Diet Nutrition ...

  17. Colonoscopy: MedlinePlus Health Topic

    Science.gov (United States)

    ... Spanish Virtual colonoscopy (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Colonoscopy updates by ... Colonoscopy Colonoscopy discharge Sigmoidoscopy Virtual colonoscopy Related Health Topics Colonic Diseases Colonic Polyps Colorectal Cancer National Institutes ...

  18. Pneumocystis Infections: MedlinePlus Health Topic

    Science.gov (United States)

    ... Pneumocystis jiroveci pneumonia (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Pneumocystis Infections updates ... GO MEDICAL ENCYCLOPEDIA Pneumocystis jiroveci pneumonia Related Health Topics HIV/AIDS HIV/AIDS and Infections Pneumonia National ...

  19. Collapsed Lung: MedlinePlus Health Topic

    Science.gov (United States)

    ... Spanish Pneumothorax - infants (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Collapsed Lung updates ... Lung surgery Pneumothorax - slideshow Pneumothorax - infants Related Health Topics Chest Injuries and Disorders Lung Diseases Pleural Disorders ...

  20. Male Infertility: MedlinePlus Health Topic

    Science.gov (United States)

    ... Spanish Testicular biopsy (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Male Infertility updates ... analysis Sperm release pathway Testicular biopsy Related Health Topics Assisted Reproductive Technology Female Infertility Infertility National Institutes ...

  1. Prediabetes:MedlinePlus Health Topic

    Science.gov (United States)

    ... in Spanish Prediabetes (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Prediabetes updates by ... Glucose tolerance test - non-pregnant Prediabetes Related Health Topics A1C Diabetes Diabetes in Children and Teens Diabetes ...

  2. Healthy Aging: MedlinePlus Health Topic

    Science.gov (United States)

    ... Aging National Institute on Aging Also in Spanish Topic Image MedlinePlus Email Updates Get Healthy Aging updates ... 65 Health screening - women - over 65 Related Health Topics Exercise for Seniors Nutrition for Seniors Seniors' Health ...

  3. Psoriatic Arthritis: MedlinePlus Health Topic

    Science.gov (United States)

    ... Handouts Psoriatic arthritis (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Psoriatic Arthritis updates ... this? GO MEDICAL ENCYCLOPEDIA Psoriatic arthritis Related Health Topics Arthritis Psoriasis National Institutes of Health The primary ...

  4. Hip Replacement: MedlinePlus Health Topic

    Science.gov (United States)

    ... invasive hip replacement (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Hip Replacement updates ... replacement - precautions Minimally invasive hip replacement Related Health Topics Hip Injuries and Disorders National Institutes of Health ...

  5. Diabetes: MedlinePlus Health Topic

    Science.gov (United States)

    ... High blood sugar (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Diabetes updates by ... ketones test Show More Show Less Related Health Topics A1C Blood Sugar Diabetes and Pregnancy Diabetes Complications ...

  6. Platelet Disorders: MedlinePlus Health Topic

    Science.gov (United States)

    ... Thromobocytopenia - drug-induced (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Platelet Disorders updates ... Willebrand disease Show More Show Less Related Health Topics Bleeding Disorders Blood Clots Blood Count Tests Blood ...

  7. Cardiac Rehabilitation: MedlinePlus Health Topic

    Science.gov (United States)

    ... in Spanish Electrocardiogram (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Cardiac Rehabilitation updates ... How to take your pulse Pulse Related Health Topics Heart Attack Heart Diseases How to Prevent Heart ...

  8. Dialysis: MedlinePlus Health Topic

    Science.gov (United States)

    ... access for hemodialysis (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Dialysis updates by ... for hemodialysis Show More Show Less Related Health Topics Creatinine Kidney Cysts Kidney Failure Peritoneal Disorders National ...

  9. Eye Wear: MedlinePlus Health Topic

    Science.gov (United States)

    ... When You Exercise (National Institute on Aging) - PDF Topic Image MedlinePlus Email Updates Get Eye Wear updates by email What's this? GO Related Health Topics Refractive Errors National Institutes of Health The primary ...

  10. Cardiac Arrest: MedlinePlus Health Topic

    Science.gov (United States)

    ... Handouts Cardiac arrest (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Cardiac Arrest updates ... this? GO MEDICAL ENCYCLOPEDIA Cardiac arrest Related Health Topics Arrhythmia CPR Pacemakers and Implantable Defibrillators National Institutes ...

  11. Kawasaki Disease: MedlinePlus Health Topic

    Science.gov (United States)

    ... Spanish Kawasaki disease (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Kawasaki Disease updates ... GO MEDICAL ENCYCLOPEDIA Electrocardiogram Kawasaki disease Related Health Topics Vasculitis National Institutes of Health The primary NIH ...

  12. Diabetic Diet: MedlinePlus Health Topic

    Science.gov (United States)

    ... Sweeteners - sugar substitutes (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Diabetic Diet updates ... you have diabetes Sweeteners - sugar substitutes Related Health Topics Blood Sugar Diabetes Diabetes in Children and Teens ...

  13. Infection Control: MedlinePlus Health Topic

    Science.gov (United States)

    ... Staph infections - hospital (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Infection Control updates ... infections when visiting Staph infections - hospital Related Health Topics Hepatitis HIV/AIDS MRSA National Institutes of Health ...

  14. Menopause: MedlinePlus Health Topic

    Science.gov (United States)

    ... Spanish What is Menopause? (National Institute on Aging) Topic Image MedlinePlus Email Updates Get Menopause updates by ... test Menopause Types of hormone therapy Related Health Topics Hormone Replacement Therapy Menstruation Premature Ovarian Failure National ...

  15. Vaginitis: MedlinePlus Health Topic

    Science.gov (United States)

    ... Spanish Vulvovaginitis - overview (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Vaginitis updates by ... Vaginitis test - wet mount Vulvovaginitis - overview Related Health Topics Trichomoniasis Vaginal Diseases Yeast Infections Other Languages Find ...

  16. Hearing Aids: MedlinePlus Health Topic

    Science.gov (United States)

    ... for hearing loss (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Hearing Aids updates ... MEDICAL ENCYCLOPEDIA Devices for hearing loss Related Health Topics Cochlear Implants Hearing Disorders and Deafness National Institutes ...

  17. Kidney Tests: MedlinePlus Health Topic

    Science.gov (United States)

    ... Spanish Total protein (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Kidney Tests updates ... hour volume Show More Show Less Related Health Topics Kidney Cancer Kidney Diseases National Institutes of Health ...

  18. Ischemic Stroke: MedlinePlus Health Topic

    Science.gov (United States)

    ... Spanish Thrombolytic therapy (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Ischemic Stroke updates ... cardiogenic embolism Stroke - slideshow Thrombolytic therapy Related Health Topics Hemorrhagic Stroke Stroke Stroke Rehabilitation National Institutes of ...

  19. Pulmonary Rehabilitation: MedlinePlus Health Topic

    Science.gov (United States)

    ... Handouts Postural drainage (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Pulmonary Rehabilitation updates ... this? GO MEDICAL ENCYCLOPEDIA Postural drainage Related Health Topics Lung Diseases National Institutes of Health The primary ...

  20. Assessing alternative measures of tree canopy cover: Photo-interpreted NAIP and ground-based estimates

    Science.gov (United States)

    Chris Toney; Greg Liknes; Andy Lister; Dacia Meneguzzo

    2012-01-01

    In preparation for the development of the National Land Cover Database (NLCD) 2011 tree canopy cover layer, a pilot project for research and method development was completed in 2010 by the USDA Forest Service Forest Inventory and Analysis (FIA) program and Remote Sensing Applications Center (RSAC).This paper explores one of several topics investigated during the NLCD...

  1. Advanced topics in computer vision

    CERN Document Server

    Farinella, Giovanni Maria; Cipolla, Roberto

    2013-01-01

    This book presents a broad selection of cutting-edge research, covering both theoretical and practical aspects of reconstruction, registration, and recognition. The text provides an overview of challenging areas and descriptions of novel algorithms. Features: investigates visual features, trajectory features, and stereo matching; reviews the main challenges of semi-supervised object recognition, and a novel method for human action categorization; presents a framework for the visual localization of MAVs, and for the use of moment constraints in convex shape optimization; examines solutions to t

  2. OHVT technology roadmap[2000]; TOPICAL

    International Nuclear Information System (INIS)

    Bradley, R.A.

    2000-01-01

    The OHVT Technology Roadmap for 2000 presents the multiyear program plan of the U.S. DOE's Office of Heavy Vehicle Technologies (OHVT). It is an update of the 1997 plan, reflecting changes in regulations and ongoing discussions with DOE's heavy vehicle customers. The technical plan covers three classes of trucks: (1) class 7-8 (large, on-highway trucks); (2) class 3-6 (medium duty trucks); (3) class 1-2 (pickups, vans, and sport utility vehicles) as well as enabling and supporting technologies. The Roadmap documents program goals, schedules, and milestones

  3. Eulerian Graphs and Related Topics

    CERN Document Server

    Fleischner, Herbert

    1990-01-01

    The two volumes comprising Part 1 of this work embrace the theme of Eulerian trails and covering walks. They should appeal both to researchers and students, as they contain enough material for an undergraduate or graduate graph theory course which emphasizes Eulerian graphs, and thus can be read by any mathematician not yet familiar with graph theory. But they are also of interest to researchers in graph theory because they contain many recent results, some of which are only partial solutions to more general problems. A number of conjectures have been included as well. Various problems (such a

  4. Topics in quantum field theory

    International Nuclear Information System (INIS)

    Svaiter, N.F.

    2006-11-01

    This paper presents some important aspects on quantum field theory, covering the following aspects: the triumph and limitations of the quantum field theory; the field theory in curved spaces - Hawking and Unruh-Davies effects; the problem of divergent theory of the zero-point; the problem of the spinning detector and the Trocheries-Takeno vacuum; the field theory at finite temperature - symmetry breaking and phase transition; the problem of the summability of the perturbative series and the perturbative expansion for the strong coupling; quantized fields in presence of classical macroscopic structures; the Parisi-Wu stochastic quantization method

  5. Is cost-covering remuneration fully booked? - Teething problems

    International Nuclear Information System (INIS)

    Niederhaeusern, A.

    2009-01-01

    In this interview with Michael Kaufmann, director of the SwissEnergy programme, possible strategies for the correct pricing of electricity and measures for the correction of the dissatisfactory situation now prevailing concerning the cost-covering remuneration of power from renewable sources are discussed. The pricing of electricity from various sources and the indirect costs that are at present not met by non-renewable resources are commented on. Further topics covered include suggestions for strategies for relieving the presently blocked financial promotion of renewables, the goals set for the role to be played by renewable energy in Swiss electricity production in 2030 and suggestions for future political action

  6. Topical report review status: Volume 10

    International Nuclear Information System (INIS)

    1996-03-01

    This report provides industry with procedures for submitting topical reports, guidance on how the U.S. Nuclear Regulatory Commission (NRC) processes and responds to topical report submittals, and an accounting, with review schedules, of all topical reports currently accepted for review by the NRC. This report is published annually

  7. Topic modelling in the information warfare domain

    CSIR Research Space (South Africa)

    De Waal, A

    2013-11-01

    Full Text Available for interesting and relevant topics. The objectives of this paper is to describe topic modelling, put it in context as a useful IW technique and illustrate its use with two examples. They discuss several applications of topic modelling in the safety and security...

  8. Credibility improves topical blog post retrieval

    NARCIS (Netherlands)

    Weerkamp, W.; de Rijke, M.

    2008-01-01

    Topical blog post retrieval is the task of ranking blog posts with respect to their relevance for a given topic. To improve topical blog post retrieval we incorporate textual credibility indicators in the retrieval process. We consider two groups of indicators: post level (determined using

  9. The art of the cover.

    Science.gov (United States)

    Porter, Nora

    2017-07-01

    Often, it's difficult to match up our cover artwork with the subjects of our lead articles and special reports. Of necessity, we sometimes turn to pure abstraction. How else to illustrate technical policy articles on subjects such as changing research protocols or informed consent, or abstract ideas like congruence, duality, imbalance, causality? At such times, we have to be pretty creative, and my search for cover art can be long and challenging. In the end, we hope that the reader will make the connection between cover and content. However, at other times, the subject of a lead article or special report overflows with artistic possibilities. © 2017 The Hastings Center.

  10. On numerically pluricanonical cyclic coverings

    International Nuclear Information System (INIS)

    Kulikov, V S; Kharlamov, V M

    2014-01-01

    We investigate some properties of cyclic coverings f:Y→X (where X is a complex surface of general type) branched along smooth curves B⊂X that are numerically equivalent to a multiple of the canonical class of X. Our main results concern coverings of surfaces of general type with p g =0 and Miyaoka-Yau surfaces. In particular, such coverings provide new examples of multi-component moduli spaces of surfaces with given Chern numbers and new examples of surfaces that are not deformation equivalent to their complex conjugates

  11. Antibacterial drugs in the form of sprays for the topical treatment of pyodermas and dermatoses complicated with a secondary infection

    Directory of Open Access Journals (Sweden)

    YE. V. Matushevskaya

    2014-01-01

    Full Text Available The article covers issues related to the application of topical antibacterial drugs for the treatment of pyodermic skin diseases. The author describes mechanisms of action and advantages of the topical form of antibiotics and GCS for the topical treatment of pyodermas. The article substantiates indications for the administration of topical GCS drugs in a combination with antibacterial drugs. The efficacy and safety of antibacterial and combination topical drugs such as Neomycin, Oxycort and Polcortolon TC in the form sprays for the treatment of pyodermas and complicated forms of chronic dermatosis.

  12. Ten badly explained topics in most corporate finance books

    OpenAIRE

    Fernandez, Pablo

    2012-01-01

    This paper addresses 10 corporate finance topics that are not well treated (or not treated at all) in many Corporate Finance Books. The topics are: 1. Where does the WACC equation come from? 2. The WACC is not a cost. 3. What is the WACC equation when the value of the debt is not equal to its nominal value? 4. The term equity premium is used to designate four different concepts. 5. Textbooks differ a lot on their recommendations regarding the equity premium. 6. Which Equity Premium is used by...

  13. Topical tacrolimus for atopic dermatitis.

    Science.gov (United States)

    Cury Martins, Jade; Martins, Ciro; Aoki, Valeria; Gois, Aecio F T; Ishii, Henrique A; da Silva, Edina M K

    2015-07-01

    Atopic dermatitis (AD) (or atopic eczema) is a chronic inflammatory skin condition that affects children and adults and has an important impact on quality of life. Topical corticosteroids (TCS) are the first-line therapy for this condition; however, they can be associated with significant adverse effects when used chronically. Tacrolimus ointment (in its 2 manufactured strengths of 0.1% and 0.03%) might be an alternative treatment. Tacrolimus, together with pimecrolimus, are drugs called topical calcineurin inhibitors (TCIs). To assess the efficacy and safety of topical tacrolimus for moderate and severe atopic dermatitis compared with other active treatments. We searched the following databases up to 3 June 2015: the Cochrane Skin Group Specialised Register, CENTRAL in the Cochrane Library (Issue 5, 2015), MEDLINE (from 1946), EMBASE (from 1974), LILACS (from 1982), and the Global Resource of Eczema Trials (GREAT database). We searched six trials registers and checked the bibliographies of included studies for further references to relevant trials. We contacted specialists in the field for unpublished data.A separate search for adverse effects of topical tacrolimus was undertaken in MEDLINE and EMBASE on 30 July 2013. We also scrutinised the U.S. Food and Drug Administration (FDA) websites for adverse effects information. All randomised controlled trials (RCTs) of participants with moderate to severe atopic dermatitis (both children and adults) using topical tacrolimus at any dose, course duration, and follow-up time compared with other active treatments. Two authors independently screened and examined the full text of selected studies for compliance with eligibility criteria, risk of bias, and data extraction. Our three prespecified primary outcomes were physician's assessment, participant's self-assessment of improvement, and adverse effects. Our secondary outcomes included assessment of improvement of the disease by validated or objective measures, such as

  14. Recent advances and perspectives in topical oral anesthesia.

    Science.gov (United States)

    Franz-Montan, Michelle; Ribeiro, Lígia Nunes de Morais; Volpato, Maria Cristina; Cereda, Cintia Maria Saia; Groppo, Francisco Carlos; Tofoli, Giovana Randomille; de Araújo, Daniele Ribeiro; Santi, Patrizia; Padula, Cristina; de Paula, Eneida

    2017-05-01

    Topical anesthesia is widely used in dentistry to reduce pain caused by needle insertion and injection of the anesthetic. However, successful anesthesia is not always achieved using the formulations that are currently commercially available. As a result, local anesthesia is still one of the procedures that is most feared by dental patients. Drug delivery systems (DDSs) provide ways of improving the efficacy of topical agents. Areas covered: An overview of the structure and permeability of oral mucosa is given, followed by a review of DDSs designed for dental topical anesthesia and their related clinical trials. Chemical approaches to enhance permeation and anesthesia efficacy, or to promote superficial anesthesia, include nanostructured carriers (liposomes, cyclodextrins, polymeric nanoparticle systems, solid lipid nanoparticles, and nanostructured lipid carriers) and different pharmaceutical dosage forms (patches, bio- and mucoadhesive systems, and hydrogels). Physical methods include pre-cooling, vibration, iontophoresis, and microneedle arrays. Expert opinion: The combination of different chemical and physical methods is an attractive option for effective topical anesthesia in oral mucosa. This comprehensive review should provide the readers with the most relevant options currently available to assist pain-free dental anesthesia. The findings should be considered for future clinical trials.

  15. 2nd Topical Workshop on Laser Technology and Optics Design

    CERN Document Server

    2013-01-01

    Lasers have a variety of applications in particle accelerator operation and will play a key role in the development of future particle accelerators by improving the generation of high brightness electron and exotic ion beams and through increasing the acceleration gradient. Lasers will also make an increasingly important contribution to the characterization of many complex particle beams by means of laser-based beam diagnostics methods. The second LANET topical workshop will address the key aspects of laser technology and optics design relevant to laser application to accelerators. The workshop will cover general optics design, provide an overview of different laser sources and discuss methods to characterize beams in details. Participants will be able to choose from a range of topical areas that go deeper in more specific aspects including tuneable lasers, design of transfer lines, noise sources and their elimination and non-linear optics effects. The format of the workshop will be mainly training-based wit...

  16. Topics in particle physics phenomenology

    International Nuclear Information System (INIS)

    Pantaleone, J.T.

    1985-01-01

    This thesis consists of topics in field theory. In part A: (Chapter 1) A short review of heavy-quark physics, (Chapter 2) Spin-dependent forces in heavy-quark systems, (Chapter 3) Bound state effects in the Upsilon → γ + resonance, and in part B, The compatibility of free fractional charge and Dirac magnetic monopoles. In Chapter 2, using the results of the fourth-order quark-antiquark interactions in perturbative QCD, we show that the spin-dependent potentials in the formalism of Eichten and Feinberg and Gromes have to be generalized to include the quark mass dependence. The recently observed hyperfine and fine structure splittings in the J/psi and Upsilon systems are found to agree with the purely perturbative QCD results for the scale parameter Λ/sub MS/ = 0.30 +/- 0.06 GeV. With this value for Λ/sub MS/ we give some predictions on the T and toponium spectroscopies. In Chapter 3 we study the effect of b anti b bound state dynamics on the reaction Upsilon → γ + resonance. We argue from the results that the recently discovered sigma (8320) must have a scalar, rather than a pseudoscalar, coupling to the b quark

  17. Decision Point 1 Topical Report

    Energy Technology Data Exchange (ETDEWEB)

    Yablonsky, Al; Barsoumian, Shant; Legere, David

    2013-05-01

    This Topical Report addresses accomplishments achieved during Phase 2a of the SkyMine® Carbon Mineralization Pilot Project. The primary objectives of this project are to design, construct, and operate a system to capture CO2 from a slipstream of flue gas from a commercial coal-fired cement kiln, convert that CO2 to products having commercial value (i.e., beneficial use), show the economic viability of the CO2 capture and conversion process, and thereby advance the technology to the point of readiness for commercial scale demonstration and proliferation. The overall process is carbon negative, resulting in mineralization of CO2 that would otherwise be released into the atmosphere. The project will also substantiate market opportunities for the technology by sales of chemicals into existing markets, and identify opportunities to improve technology performance and reduce costs at the commercial scale. The project is being conducted in two phases. The primary objectives of Phase 1 were to elaborate proven SkyMine® process chemistry to commercial pilot-scale operation and complete the preliminary design for the pilot plant to be built and operated in Phase 2, complete a NEPA evaluation, and develop a comprehensive carbon life cycle analysis. The objective of the current Phase (2a) is to complete the detailed design of the pilot plant to be built in Phase 2b.

  18. Main technical topics in 1999

    International Nuclear Information System (INIS)

    2000-01-01

    This Safety Authority annual report strives to present current organizational provisions and future trends in nuclear safety supervision in France and to describe the most outstanding occurrences during the past year. A first part presents nine documents concerning the main topics of 1999: aging of nuclear installations, the Offsite Emergency Plans (PPI), the impact of nuclear activities on man and the environment, the criticality hazards, EDF in 1999, the EPR project, the Andra in 1999, the transport incidents, the nuclear safety in eastern Europe. The second part presents the missions and actions of the Nuclear Installations Safety in the domains of the liabilities, the organization of the nuclear safety control, the regulations of the INB, the public information, the international relations, the crisis management, the radioactive materials transportation, the radioactive wastes. The equipment, the radiation protection and the exploitation of the pressurized water reactors are also treated just as the experimental reactors, the fuel cycle installations and the the nuclear installations dismantling. (A.L.B.)

  19. Topics in Number Theory Conference

    CERN Document Server

    Andrews, George; Ono, Ken

    1999-01-01

    From July 31 through August 3,1997, the Pennsylvania State University hosted the Topics in Number Theory Conference. The conference was organized by Ken Ono and myself. By writing the preface, I am afforded the opportunity to express my gratitude to Ken for beng the inspiring and driving force behind the whole conference. Without his energy, enthusiasm and skill the entire event would never have occurred. We are extremely grateful to the sponsors of the conference: The National Sci­ ence Foundation, The Penn State Conference Center and the Penn State Depart­ ment of Mathematics. The object in this conference was to provide a variety of presentations giving a current picture of recent, significant work in number theory. There were eight plenary lectures: H. Darmon (McGill University), "Non-vanishing of L-functions and their derivatives modulo p. " A. Granville (University of Georgia), "Mean values of multiplicative functions. " C. Pomerance (University of Georgia), "Recent results in primality testing. " C. ...

  20. The Virtual Robotics Laboratory; TOPICAL

    International Nuclear Information System (INIS)

    Kress, R.L.; Love, L.J.

    1999-01-01

    The growth of the Internet has provided a unique opportunity to expand research collaborations between industry, universities, and the national laboratories. The Virtual Robotics Laboratory (VRL) is an innovative program at Oak Ridge National Laboratory (ORNL) that is focusing on the issues related to collaborative research through controlled access of laboratory equipment using the World Wide Web. The VRL will provide different levels of access to selected ORNL laboratory secondary education programs. In the past, the ORNL Robotics and Process Systems Division has developed state-of-the-art robotic systems for the Army, NASA, Department of Energy, Department of Defense, as well as many other clients. After proof of concept, many of these systems sit dormant in the laboratories. This is not out of completion of all possible research topics. but from completion of contracts and generation of new programs. In the past, a number of visiting professors have used this equipment for their own research. However, this requires that the professor, and possibly his/her students, spend extended periods at the laboratory facility. In addition, only a very exclusive group of faculty can gain access to the laboratory and hardware. The VRL is a tool that enables extended collaborative efforts without regard to geographic limitations

  1. Topical subjects of nuclear energy

    International Nuclear Information System (INIS)

    1977-12-01

    The controversy as regards the introduction of nuclear energy to the energy supply of the Federal Republic of Germany has not subdued yet. However, the discussion has shifted from technical questions more to the field of political argumentation. In addition, questions concerning the back end cycle have come to the fore. The report at hand deals with the topical subjects of fuel reprocessing, ultimate storage of radioactive wastes, the impact of power plants in general and nuclear power plants in particular on the climate, safety and safeguard questions concerning nuclear facilities and fissionable materials, and with the properties and possibilities of plutonium. The authors tried to present technical know-how in an easy comprehensible way. Literature references enable the checking of facts and provide the possibility to deal in more detail with the matter. The seminar report is to give all those interested the opportunity to acquaint themselves with facts and know-how and to acquire knowledge on which to base a personal opinion. (orig.) [de

  2. Topical papers on raw materials

    International Nuclear Information System (INIS)

    1978-01-01

    In the papers of this working group, the availability of uranium and the long-term supply situation for this raw material are discussed. A problem closely connected with uranium supply are the commercial contracts and their particularities. The points of view of the reporting countries of Great Britain, South Africa, Switzerland, Australia, Japan, and Korea are made clear

  3. Identifying Topics in Microblogs Using Wikipedia.

    Directory of Open Access Journals (Sweden)

    Ahmet Yıldırım

    Full Text Available Twitter is an extremely high volume platform for user generated contributions regarding any topic. The wealth of content created at real-time in massive quantities calls for automated approaches to identify the topics of the contributions. Such topics can be utilized in numerous ways, such as public opinion mining, marketing, entertainment, and disaster management. Towards this end, approaches to relate single or partial posts to knowledge base items have been proposed. However, in microblogging systems like Twitter, topics emerge from the culmination of a large number of contributions. Therefore, identifying topics based on collections of posts, where individual posts contribute to some aspect of the greater topic is necessary. Models, such as Latent Dirichlet Allocation (LDA, propose algorithms for relating collections of posts to sets of keywords that represent underlying topics. In these approaches, figuring out what the specific topic(s the keyword sets represent remains as a separate task. Another issue in topic detection is the scope, which is often limited to specific domain, such as health. This work proposes an approach for identifying domain-independent specific topics related to sets of posts. In this approach, individual posts are processed and then aggregated to identify key tokens, which are then mapped to specific topics. Wikipedia article titles are selected to represent topics, since they are up to date, user-generated, sophisticated articles that span topics of human interest. This paper describes the proposed approach, a prototype implementation, and a case study based on data gathered during the heavily contributed periods corresponding to the four US election debates in 2012. The manually evaluated results (0.96 precision and other observations from the study are discussed in detail.

  4. Identifying Topics in Microblogs Using Wikipedia.

    Science.gov (United States)

    Yıldırım, Ahmet; Üsküdarlı, Suzan; Özgür, Arzucan

    2016-01-01

    Twitter is an extremely high volume platform for user generated contributions regarding any topic. The wealth of content created at real-time in massive quantities calls for automated approaches to identify the topics of the contributions. Such topics can be utilized in numerous ways, such as public opinion mining, marketing, entertainment, and disaster management. Towards this end, approaches to relate single or partial posts to knowledge base items have been proposed. However, in microblogging systems like Twitter, topics emerge from the culmination of a large number of contributions. Therefore, identifying topics based on collections of posts, where individual posts contribute to some aspect of the greater topic is necessary. Models, such as Latent Dirichlet Allocation (LDA), propose algorithms for relating collections of posts to sets of keywords that represent underlying topics. In these approaches, figuring out what the specific topic(s) the keyword sets represent remains as a separate task. Another issue in topic detection is the scope, which is often limited to specific domain, such as health. This work proposes an approach for identifying domain-independent specific topics related to sets of posts. In this approach, individual posts are processed and then aggregated to identify key tokens, which are then mapped to specific topics. Wikipedia article titles are selected to represent topics, since they are up to date, user-generated, sophisticated articles that span topics of human interest. This paper describes the proposed approach, a prototype implementation, and a case study based on data gathered during the heavily contributed periods corresponding to the four US election debates in 2012. The manually evaluated results (0.96 precision) and other observations from the study are discussed in detail.

  5. 75 FR 26647 - Ophthalmic and Topical Dosage Form New Animal Drugs; Ivermectin Topical Solution

    Science.gov (United States)

    2010-05-12

    .... FDA-2010-N-0002] Ophthalmic and Topical Dosage Form New Animal Drugs; Ivermectin Topical Solution... are treated with a topical solution of ivermectin. DATES: This rule is effective May 12, 2010. FOR... ANADA 200-340 for PRIVERMECTIN (ivermectin), a topical solution used on cattle to control infestations...

  6. Topical tags vs non-topical tags : Towards a bipartite classification?

    NARCIS (Netherlands)

    Basile, Valerio; Peroni, Silvio; Tamburini, Fabio; Vitali, Fabio

    2015-01-01

    In this paper we investigate whether it is possible to create a computational approach that allows us to distinguish topical tags (i.e. talking about the topic of a resource) and non-topical tags (i.e. describing aspects of a resource that are not related to its topic) in folksonomies, in a way that

  7. Meeting of the ITPA Topical Group on Diagnostics

    International Nuclear Information System (INIS)

    Costley, A.E.; Donne, A.J.H.

    2002-01-01

    The first meeting of the International Tokamak Physics Activities (ITPA) Topical Group (TG) on diagnostics was held at the Ioffe Physical-Technical institute, St. Petersburg, Russian Federation, on 14-16 November 2001. In total 38 participants attended the meeting and all four ITPA partners (EU, JA, RF and US) were represented. This summary covers mainly the discussions at the TG meeting. The meeting immediately followed a progress meeting, held in the same location on 12-13 November 2001, on the efforts carried out in the Russian Federation on diagnostics for ITER and burning plasma experiments

  8. What Patients Can Tell Us: Topic Analysis for Social Media on Breast Cancer.

    Science.gov (United States)

    Tapi Nzali, Mike Donald; Bringay, Sandra; Lavergne, Christian; Mollevi, Caroline; Opitz, Thomas

    2017-07-31

    Social media dedicated to health are increasingly used by patients and health professionals. They are rich textual resources with content generated through free exchange between patients. We are proposing a method to tackle the problem of retrieving clinically relevant information from such social media in order to analyze the quality of life of patients with breast cancer. Our aim was to detect the different topics discussed by patients on social media and to relate them to functional and symptomatic dimensions assessed in the internationally standardized self-administered questionnaires used in cancer clinical trials (European Organization for Research and Treatment of Cancer [EORTC] Quality of Life Questionnaire Core 30 [QLQ-C30] and breast cancer module [QLQ-BR23]). First, we applied a classic text mining technique, latent Dirichlet allocation (LDA), to detect the different topics discussed on social media dealing with breast cancer. We applied the LDA model to 2 datasets composed of messages extracted from public Facebook groups and from a public health forum (cancerdusein.org, a French breast cancer forum) with relevant preprocessing. Second, we applied a customized Jaccard coefficient to automatically compute similarity distance between the topics detected with LDA and the questions in the self-administered questionnaires used to study quality of life. Among the 23 topics present in the self-administered questionnaires, 22 matched with the topics discussed by patients on social media. Interestingly, these topics corresponded to 95% (22/23) of the forum and 86% (20/23) of the Facebook group topics. These figures underline that topics related to quality of life are an important concern for patients. However, 5 social media topics had no corresponding topic in the questionnaires, which do not cover all of the patients' concerns. Of these 5 topics, 2 could potentially be used in the questionnaires, and these 2 topics corresponded to a total of 3.10% (523

  9. Recent Advances In Topical Therapy In Dermatology

    Directory of Open Access Journals (Sweden)

    Mohan Thappa Devinder

    2003-01-01

    Full Text Available With changing times various newer topical agents are introduced in the field of dermatology. Tacrolimus and pimecrolimus are immunisuppressants, which are effective topically and are tried in the management of atopic dermatitis as well as other disorders including allergic contact dermatitis, atrophic lichen planus, pyoderma gangrenosum. Imiquimod, an immune response modifier, is presently in use for genital warts but has potentials as anti- tumour agent and in various other dermatological conditions when used topically. Tazarotene is a newer addition to the list of topical reginoids, which is effective in psoriasis and has better effect in combination with calcipotriene, phototherapy and topical costicosteroids. Tazarotene and adapelene are also effective in inflammatory acne. Calcipotriol, a vitamin D analogue has been introduced as a topical agent in the treatment of psoriasis. Steroid components are also developed recently which will be devoid of the side effects but having adequate anti-inflammatory effect. Topical photodynamic therapy has also a wide range of use in dermatology. Newer topical agents including cidofovir, capsaicin, topical sensitizers, topical antifungal agents for onychomycosis are also of use in clinical practice. Other promising developments include skin substitutes and growth factors for wound care.

  10. Flammable gas project topical report

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, G.D.

    1997-01-29

    The flammable gas safety issue was recognized in 1990 with the declaration of an unreviewed safety question (USQ) by the U. S. Department of Energy as a result of the behavior of the Hanford Site high-level waste tank 241-SY-101. This tank exhibited episodic releases of flammable gas that on a couple of occasions exceeded the lower flammability limit of hydrogen in air. Over the past six years there has been a considerable amount of knowledge gained about the chemical and physical processes that govern the behavior of tank 241-SY-1 01 and other tanks associated with the flammable gas safety issue. This report was prepared to provide an overview of that knowledge and to provide a description of the key information still needed to resolve the issue. Items covered by this report include summaries of the understanding of gas generation, retention and release mechanisms, the composition and flammability behavior of the gas mixture, the amounts of stored gas, and estimated gas release fractions for spontaneous releases. `Me report also discusses methods being developed for evaluating the 177 tanks at the Hanford Site and the problems associated with these methods. Means for measuring the gases emitted from the waste are described along with laboratory experiments designed to gain more information regarding rates of generation, species of gases emitted and modes of gas storage and release. Finally, the process for closing the USQ is outlined as are the information requirements to understand and resolve the flammable gas issue.

  11. Mekong Land Cover Dasboard: Regional Land Cover Mointoring Systems

    Science.gov (United States)

    Saah, D. S.; Towashiraporn, P.; Aekakkararungroj, A.; Phongsapan, K.; Triepke, J.; Maus, P.; Tenneson, K.; Cutter, P. G.; Ganz, D.; Anderson, E.

    2016-12-01

    SERVIR-Mekong, a USAID-NASA partnership, helps decision makers in the Lower Mekong Region utilize GIS and Remote Sensing information to inform climate related activities. In 2015, SERVIR-Mekong conducted a geospatial needs assessment for the Lower Mekong countries which included individual country consultations. The team found that many countries were dependent on land cover and land use maps for land resource planning, quantifying ecosystem services, including resilience to climate change, biodiversity conservation, and other critical social issues. Many of the Lower Mekong countries have developed national scale land cover maps derived in part from remote sensing products and geospatial technologies. However, updates are infrequent and classification systems do not always meet the needs of key user groups. In addition, data products stop at political boundaries and are often not accessible making the data unusable across country boundaries and with resource management partners. Many of these countries rely on global land cover products to fill the gaps of their national efforts, compromising consistency between data and policies. These gaps in national efforts can be filled by a flexible regional land cover monitoring system that is co-developed by regional partners with the specific intention of meeting national transboundary needs, for example including consistent forest definitions in transboundary watersheds. Based on these facts, key regional stakeholders identified a need for a land cover monitoring system that will produce frequent, high quality land cover maps using a consistent regional classification scheme that is compatible with national country needs. SERVIR-Mekong is currently developing a solution that leverages recent developments in remote sensing science and technology, such as Google Earth Engine (GEE), and working together with production partners to develop a system that will use a common set of input data sources to generate high

  12. Learning From Short Text Streams With Topic Drifts.

    Science.gov (United States)

    Li, Peipei; He, Lu; Wang, Haiyan; Hu, Xuegang; Zhang, Yuhong; Li, Lei; Wu, Xindong

    2017-09-18

    Short text streams such as search snippets and micro blogs have been popular on the Web with the emergence of social media. Unlike traditional normal text streams, these data present the characteristics of short length, weak signal, high volume, high velocity, topic drift, etc. Short text stream classification is hence a very challenging and significant task. However, this challenge has received little attention from the research community. Therefore, a new feature extension approach is proposed for short text stream classification with the help of a large-scale semantic network obtained from a Web corpus. It is built on an incremental ensemble classification model for efficiency. First, more semantic contexts based on the senses of terms in short texts are introduced to make up of the data sparsity using the open semantic network, in which all terms are disambiguated by their semantics to reduce the noise impact. Second, a concept cluster-based topic drifting detection method is proposed to effectively track hidden topic drifts. Finally, extensive studies demonstrate that as compared to several well-known concept drifting detection methods in data stream, our approach can detect topic drifts effectively, and it enables handling short text streams effectively while maintaining the efficiency as compared to several state-of-the-art short text classification approaches.

  13. The National Land Cover Database

    Science.gov (United States)

    Homer, Collin G.; Fry, Joyce A.; Barnes, Christopher A.

    2012-01-01

    The National Land Cover Database (NLCD) serves as the definitive Landsat-based, 30-meter resolution, land cover database for the Nation. NLCD provides spatial reference and descriptive data for characteristics of the land surface such as thematic class (for example, urban, agriculture, and forest), percent impervious surface, and percent tree canopy cover. NLCD supports a wide variety of Federal, State, local, and nongovernmental applications that seek to assess ecosystem status and health, understand the spatial patterns of biodiversity, predict effects of climate change, and develop land management policy. NLCD products are created by the Multi-Resolution Land Characteristics (MRLC) Consortium, a partnership of Federal agencies led by the U.S. Geological Survey. All NLCD data products are available for download at no charge to the public from the MRLC Web site: http://www.mrlc.gov.

  14. Engineered soil covers for management of salt impacted sites

    International Nuclear Information System (INIS)

    Sweeney, D.A.; Tratch, D.J.

    2005-01-01

    The use of engineered soil cover systems to mitigate environmental impacts from tailings and waste rock piles is becoming an accepted practice. This paper presented design concepts for soil covers related to reclamation practices in the mining industry as an effective risk management practice at salt impacted sites. Research and field programs have demonstrated that a layered engineered soil cover can reduce or eliminate infiltration. Key components of the system included re-establishing surface vegetation to balance precipitation fluxes with evapotranspiration potential, and design of a capillary break below the rooting zone to minimize deeper seated infiltration. It was anticipated that the incorporation of a vegetation cover and a capillary break would minimize infiltration into the waste rock or tailing pile and reduce the generation of acid rock drainage (ARD). Design of a layered soil cover requires the incorporation of meteorological data, moisture retention characteristics of the impacted soils, and proposed engineered cover materials. Performance of the soil cover was predicted using a finite element model combined with meteorological data from the site area, unsaturated soil properties of the parent sub-surface soils and potential covered materials. The soil cover design consisted of re-vegetation and a loose clay cover overlying a compacted till layer. The design was conducted for an off site release of salt impacted pasture land adjacent to a former highway maintenance yard. The model predicted minimal infiltration during high precipitation events and no infiltration during low precipitation events. Results indicated that the proposed soil cover would enable re-establishment of a productive agricultural ground cover, as well as minimizing the potential for additional salt migration. It was concluded that further research and development is needed to ensure that the cover system is an acceptable method for long-term risk management. 17 refs., 5 figs

  15. Topical Session on the Decommissioning and Dismantling Safety Case

    International Nuclear Information System (INIS)

    2002-01-01

    practices is low, the idea being that it is important to understand differences in approaches. Frances Taylor, Head of Radioactive Waste Management and Decommissioning Strategy Unit, HM Nuclear Installations Inspectorate, Health and Safety Executive, served as Session Chair. Scott Moore, Section Chief of the Special Projects section, U.S. Nuclear Regulatory Commission, served as the Rapporteur for the Topical Session. Presentations during the topical session covered key aspects of the safety case, including: - international requirements and guidance, - environmental impact assessment, - plant configuration and decommissioning and dismantling (D and D) licensing, - accident assessment, - balancing radiological and industrial risk, and - the safety case for safe store and dormancy periods. At the end of each presentation time was allotted for discussion of the paper. Integral to the Topical Session was a facilitated plenary discussion on the topical issues identified above. The Rapporteur briefly reviewed the main points at the end of the topical session. The Topical Session is documented as follows. First a summary of the presentations is given along with the questions that were asked of each speaker; then follow a summary of the plenary discussions and the main points made. The extended abstracts or full papers supporting each presentation are given in Appendix 1. As a follow-on to the Topical Session a Task Group has been constituted in order to propose to the WPDD a more detailed work programme in this area

  16. A Discourse Perspective of Topic-prominence in Chinese EFL Learners’ Interlanguage

    Directory of Open Access Journals (Sweden)

    Shaopeng Li

    2014-07-01

    Full Text Available The present study aims to investigate the general characteristics of topic-prominent typological interlanguage development of Chinese learners of English in terms of acquiring subject-prominent English structures from the discourse perspective. We have selected as the research target “topic chain” which is the main topic-prominent structure in Chinese discourse and “zero anaphora” which is the most common topic anaphor of topic chain. Topic structures mainly appear in Chinese discourse in the form of “topic chain” (Wang, 2002; 2004. Actually, in the event of a topic chain, research on topic structures should go into the typical range of discourse. Two important findings were yielded by the present study. First, the characteristics of Chinese topic chain are transferrable to the interlanguage of Chinese EFL learners, thus resulting in overgeneralization of zero anaphora; second, interlanguage discourse of Chinese EFL learners reflects the characteristics of a second language acquisition process from topic-prominence to subject-prominence, thus lending support to the discourse transfer hypothesis.

  17. Topics in Gravitation and Cosmology

    Science.gov (United States)

    Bahrami Taghanaki, Sina

    This thesis is focused on two topics in which relativistic gravitational fields play an important role, namely early Universe cosmology and black hole physics. The theory of cosmic inflation has emerged as the most successful theory of the very early Universe with concrete and verifiable predictions for the properties of anisotropies of the cosmic microwave background radiation and large scale structure. Coalescences of black hole binaries have recently been detected by the Laser Interferometer Gravitational Wave Observatory (LIGO), opening a new arena for observationally testing the dynamics of gravity. In part I of this thesis we explore some modifications to the standard theory of inflation. The main predictions of single field slow-roll inflation have been largely consistent with cosmological observations. However, there remain some aspects of the theory that are not presently well understood. Among these are the somewhat interrelated issues of the choice of initial state for perturbations and the potential imprints of pre-inflationary dynamics. It is well known that a key prediction of the standard theory of inflation, namely the Gaussianity of perturbations, is a consequence of choosing a natural vacuum initial state. In chapter 3, we study the generation and detectability of non-Gaussianities in inflationary scalar perturbations that originate from more general choices of initial state. After that, in chapter 4, we study a simple but predictive model of pre-inflationary dynamics in an attempt to test the robustness of inflationary predictions. We find that significant deviations from the standard predictions are unlikely to result from models in which the inflaton field decouples from the pre-inflationary degrees of freedom prior to freeze-out of the observable modes. In part II we turn to a study of an aspect of the thermodynamics of black holes, a subject which has led to important advances in our understanding of quantum gravity. For objects which

  18. Topics in elementary particle physics

    Science.gov (United States)

    Jin, Xiang

    The author of this thesis discusses two topics in elementary particle physics: n-ary algebras and their applications to M-theory (Part I), and functional evolution and Renormalization Group flows (Part II). In part I, Lie algebra is extended to four different n-ary algebraic structure: generalized Lie algebra, Filippov algebra, Nambu algebra and Nambu-Poisson tensor; though there are still many other n-ary algebras. A natural property of Generalized Lie algebras — the Bremner identity, is studied, and proved with a totally different method from its original version. We extend Bremner identity to n-bracket cases, where n is an arbitrary odd integer. Filippov algebras do not focus on associativity, and are defined by the Fundamental identity. We add associativity to Filippov algebras, and give examples of how to construct Filippov algebras from su(2), bosonic oscillator, Virasoro algebra. We try to include fermionic charges into the ternary Virasoro-Witt algebra, but the attempt fails because fermionic charges keep generating new charges that make the algebra not closed. We also study the Bremner identity restriction on Nambu algebras and Nambu-Poisson tensors. So far, the only example 3-algebra being used in physics is the BLG model with 3-algebra A4, describing two M2-branes interactions. Its extension with Nambu algebra, BLG-NB model, is believed to describe infinite M2-branes condensation. Also, there is another propose for M2-brane interactions, the ABJM model, which is constructed by ordinary Lie algebra. We compare the symmetry properties between them, and discuss the possible approaches to include these three models into a grand unification theory. In Part II, we give an approximate solution for Schroeder's equations, based on series and conjugation methods. We use the logistic map as an example, and demonstrate that this approximate solution converges to known analytical solutions around the fixed point, around which the approximate solution is constructed

  19. Unsupervised topic discovery by anomaly detection

    OpenAIRE

    Cheng, Leon

    2013-01-01

    Approved for public release; distribution is unlimited With the vast amount of information and public comment available online, it is of increasing interest to understand what is being said and what topics are trending online. Government agencies, for example, want to know what policies concern the public without having to look through thousands of comments manually. Topic detection provides automatic identification of topics in documents based on the information content and enhances many ...

  20. Tracking topic birth and death in LDA.

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Andrew T.; Robinson, David Gerald

    2011-09-01

    Most topic modeling algorithms that address the evolution of documents over time use the same number of topics at all times. This obscures the common occurrence in the data where new subjects arise and old ones diminish or disappear entirely. We propose an algorithm to model the birth and death of topics within an LDA-like framework. The user selects an initial number of topics, after which new topics are created and retired without further supervision. Our approach also accommodates many of the acceleration and parallelization schemes developed in recent years for standard LDA. In recent years, topic modeling algorithms such as latent semantic analysis (LSA)[17], latent Dirichlet allocation (LDA)[10] and their descendants have offered a powerful way to explore and interrogate corpora far too large for any human to grasp without assistance. Using such algorithms we are able to search for similar documents, model and track the volume of topics over time, search for correlated topics or model them with a hierarchy. Most of these algorithms are intended for use with static corpora where the number of documents and the size of the vocabulary are known in advance. Moreover, almost all current topic modeling algorithms fix the number of topics as one of the input parameters and keep it fixed across the entire corpus. While this is appropriate for static corpora, it becomes a serious handicap when analyzing time-varying data sets where topics come and go as a matter of course. This is doubly true for online algorithms that may not have the option of revising earlier results in light of new data. To be sure, these algorithms will account for changing data one way or another, but without the ability to adapt to structural changes such as entirely new topics they may do so in counterintuitive ways.

  1. Topic Time Series Analysis of Microblogs

    Science.gov (United States)

    2014-10-01

    may be distributed more globally. Tweets on a specific topic that cluster spatially, temporally or both might be of interest to analysts, marketers ...of $ and @, with the latter only in the case that it is the only character in the token (the @ symbol is significant in its usage by Instagram in...is generated by Instagram . Topic 80, Distance: 143.2101 Top words: 1. rawr 2. ˆ0ˆ 3. kill 4. jurassic 5. dinosaur Analysis: This topic is quite

  2. Updates of Topical and Local Anesthesia Agents.

    Science.gov (United States)

    Boyce, Ricardo A; Kirpalani, Tarun; Mohan, Naveen

    2016-04-01

    As described in this article, there are many advances in topical and local anesthesia. Topical and local anesthetics have played a great role in dentistry in alleviating the fears of patients, eliminating pain, and providing pain control. Many invasive procedures would not be performed without the use and advances of topical/local anesthetics. The modern-day dentist has the responsibility of knowing the variety of products on the market and should have at least references to access before, during, and after treatment. This practice ensures proper care with topical and local anesthetics for the masses of patients entering dental offices worldwide. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Topical Drug Formulations for Prolonged Corneal Anesthesia

    Science.gov (United States)

    Wang, Liqiang; Shankarappa, Sahadev A.; Tong, Rong; Ciolino, Joseph B.; Tsui, Jonathan H.; Chiang, Homer H.; Kohane, Daniel S.

    2013-01-01

    Purpose Ocular local anesthetics (OLA’s) currently used in routine clinical practice for corneal anesthesia are short acting and their ability to delay corneal healing makes them unsuitable for long-term use. In this study, we examined the effect on the duration of corneal anesthesia of the site-1 sodium channel blocker tetrodotoxin (TTX), applied with either proparacaine or the chemical permeation enhancer OTAB. The effect of test solutions on corneal healing was also studied. Methods Solutions of TTX, proparacaine, and OTAB, singly or in combination were applied topically to the rat cornea. The blink response, an indirect measure of corneal sensitivity, was recorded using a Cochet-Bonnet esthesiometer, and the duration of corneal anesthesia calculated. The effect of test compounds on the rate of corneal epithelialization was studied in vivo following corneal debridement. Results Combination of TTX and proparacaine resulted in corneal anesthesia that was 8–10 times longer in duration than that from either drug administered alone, while OTAB did not prolong anesthesia. The rate of corneal healing was moderately delayed following co-administration of TTX and proparacaine. Conclusion Co-administration of TTX and proparacaine significantly prolonged corneal anesthesia but in view of delayed corneal re-epithelialization, caution is suggested in use of the combination. PMID:23615270

  4. Emerging Infectious Diseases Cover Art

    Centers for Disease Control (CDC) Podcasts

    2017-07-26

    Byron Breedlove, managing editor of the EID Journal, discusses his approach to cover art.  Created: 7/26/2017 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 7/26/2017.

  5. Cover Crops in Hillside Agriculture

    International Development Research Centre (IDRC) Digital Library (Canada)

    Our study focuses on the wet tropical hillsides of northern Honduras (Figure 1). ..... The eastern extreme of the region (Jutiapa) is a dry spot, with less rainfall (2 000 mm a-1) as a result ...... Paper presented at the International Workshop on Green Manure–Cover Crops for Smallholders in ..... Lamaster, J.P.; Jones, I.R. 1923.

  6. Cover times of random searches

    Science.gov (United States)

    Chupeau, Marie; Bénichou, Olivier; Voituriez, Raphaël

    2015-10-01

    How long must one undertake a random search to visit all sites of a given domain? This time, known as the cover time, is a key observable to quantify the efficiency of exhaustive searches, which require a complete exploration of an area and not only the discovery of a single target. Examples range from immune-system cells chasing pathogens to animals harvesting resources, from robotic exploration for cleaning or demining to the task of improving search algorithms. Despite its broad relevance, the cover time has remained elusive and so far explicit results have been scarce and mostly limited to regular random walks. Here we determine the full distribution of the cover time for a broad range of random search processes, including Lévy strategies, intermittent strategies, persistent random walks and random walks on complex networks, and reveal its universal features. We show that for all these examples the mean cover time can be minimized, and that the corresponding optimal strategies also minimize the mean search time for a single target, unambiguously pointing towards their robustness.

  7. Safety of fuel cycle facilities. Topical issues paper no. 3

    International Nuclear Information System (INIS)

    Ranguelova, V.; Niehaus, F.; Delattre, D.

    2001-01-01

    A wide range of nuclear fuel cycle facilities are in operation. These installations process, use, store and dispose of radioactive material and cover: mining and milling, conversion, enrichment, fuel fabrication (including mixed oxide fuel), reactor, interim spent fuel storage, reprocessing, waste treatment and waste disposal facilities. For the purposes of this paper, reactors and waste disposal facilities are not considered. The term 'fuel cycle facilities' covers only the remainder of the installations listed above. The IAEA Secretariat maintains a database of fuel cycle facilities in its Member States. Known as the Nuclear Fuel Cycle Information System (NFCIS), it is available as an on-line service through the Internet. More than 500 such facilities have been reported under this system. The facilities are listed by facility type and operating status. Approximately one third of all of the facilities are located in developing States. About half of all facilities are reported to be operating, of which approximately 40% are operating in developing States. In addition, some 60 facilities are either in the design stage or under construction. Although the radioactive source term for most fuel cycle facilities is lower than the source term for reactors, which results in less severe consequences to the public from potential accidents at these fuel cycle installations, recent events at some fuel cycle facilities have given rise to public concern which has to be addressed adequately by national regulatory bodies and at the international level. Worldwide, operational experience feedback warrants improvements in the safety of these facilities. Some of the hazards are similar for reactor and non-reactor facilities. However, the differences between these installations give rise to specific safety concerns at fuel cycle facilities. In particular, these concerns include: criticality, radiation protection of workers, chemical hazards, fire and explosion hazards. It is recognized

  8. Topical herbal therapies for treating osteoarthritis.

    Science.gov (United States)

    Cameron, Melainie; Chrubasik, Sigrun

    2013-05-31

    Before extraction and synthetic chemistry were invented, musculoskeletal complaints were treated with preparations from medicinal plants. They were either administered orally or topically. In contrast to the oral medicinal plant products, topicals act in part as counterirritants or are toxic when given orally. To update the previous Cochrane review of herbal therapy for osteoarthritis from 2000 by evaluating the evidence on effectiveness for topical medicinal plant products. Databases for mainstream and complementary medicine were searched using terms to include all forms of arthritis combined with medicinal plant products. We searched electronic databases (Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, AMED, CINAHL, ISI Web of Science, World Health Organization Clinical Trials Registry Platform) to February 2013, unrestricted by language. We also searched the reference lists from retrieved trials. Randomised controlled trials of herbal interventions used topically, compared with inert (placebo) or active controls, in people with osteoarthritis were included. Two review authors independently selected trials for inclusion, assessed the risk of bias of included studies and extracted data. Seven studies (six different medicinal plant interventions; 785 participants) were included. Single studies (five studies) and non-comparable studies (two studies) precluded pooling of results.Moderate evidence from a single study of 174 people with hand osteoarthritis indicated that treatment with Arnica extract gel probably results in similar benefits as treatment with ibuprofen (non-steroidal anti-inflammatory drug) with a similar number of adverse events. Mean pain in the ibuprofen group was 44.2 points on a 100 point scale; treatment with Arnica gel reduced the pain by 4 points after three weeks: mean difference (MD) -3.8 points (95% confidence intervals (CI) -10.1 to 2.5), absolute reduction 4% (10% reduction to 3% increase). Hand function was 7

  9. Graph-based Techniques for Topic Classification of Tweets in Spanish

    Directory of Open Access Journals (Sweden)

    Hector Cordobés

    2014-03-01

    Full Text Available Topic classification of texts is one of the most interesting challenges in Natural Language Processing (NLP. Topic classifiers commonly use a bag-of-words approach, in which the classifier uses (and is trained with selected terms from the input texts. In this work we present techniques based on graph similarity to classify short texts by topic. In our classifier we build graphs from the input texts, and then use properties of these graphs to classify them. We have tested the resulting algorithm by classifying Twitter messages in Spanish among a predefined set of topics, achieving more than 70% accuracy.

  10. Anesthesia: A Topic for Interdisciplinary Study.

    Science.gov (United States)

    Labianca, Dominick A.; Reeves, William J.

    1977-01-01

    Describes an interdisciplinary approach for teaching the topic of anesthesia as one aspect of a chemistry-oriented course for nonscience majors which focuses on timely topics such as the energy crisis and drugs. Historical treatment with the examination of literature is emphasized in teaching. (HM)

  11. Exploring Topic Structure: Coherence, Diversity and Relatedness

    NARCIS (Netherlands)

    J. He (Jiyin)

    2011-01-01

    htmlabstractThe use of topical information has long been studied in the context of information retrieval. For example, grouping search results into topical categories enables more effective information presentation to users, while grouping documents in a collection can lead to efficient information

  12. Topical cholesterol in clofazimine induced ichthyosis

    Directory of Open Access Journals (Sweden)

    Pandey S

    1994-01-01

    Full Text Available Topical application of 10% cholesterol in petrolatum significantly (P< 0.05 controlled the development of ichthyosis in 62 patients taking 100 mg clofazimine daily for a period of 3 months. However, topical cholesterol application did not affect the lowering of serum cholesterol induced by oral clofazimine. Probable mechanism of action is being discussed.

  13. Infantile generalized hypertrichosis caused by topical minoxidil*

    Science.gov (United States)

    Rampon, Greice; Henkin, Caroline; de Souza, Paulo Ricardo Martins; de Almeida Jr, Hiram Larangeira

    2016-01-01

    Rare cases of hypertrichosis have been associated with topically applied minoxidil. We present the first reported case in the Brazilian literature of generalized hypertrichosis affecting a 5-year-old child, following use of minoxidil 5%, 20 drops a day, for hair loss. The laboratory investigation excluded hyperandrogenism and thyroid dysfunction. Topical minoxidil should be used with caution in children. PMID:26982785

  14. Infantile generalized hypertrichosis caused by topical minoxidil.

    Science.gov (United States)

    Rampon, Greice; Henkin, Caroline; de Souza, Paulo Ricardo Martins; Almeida, Hiram Larangeira de

    2016-01-01

    Rare cases of hypertrichosis have been associated with topically applied minoxidil. We present the first reported case in the Brazilian literature of generalized hypertrichosis affecting a 5-year-old child, following use of minoxidil 5%, 20 drops a day, for hair loss. The laboratory investigation excluded hyperandrogenism and thyroid dysfunction. Topical minoxidil should be used with caution in children.

  15. Aerodynamics of wind turbines emerging topics

    CERN Document Server

    Amano, R S

    2014-01-01

    Focusing on Aerodynamics of Wind Turbines with topics ranging from Fundamental to Application of horizontal axis wind turbines, this book presents advanced topics including: Basic Theory for Wind turbine Blade Aerodynamics, Computational Methods, and Special Structural Reinforcement Technique for Wind Turbine Blades.

  16. Correlated Topic Vector for Scene Classification.

    Science.gov (United States)

    Wei, Pengxu; Qin, Fei; Wan, Fang; Zhu, Yi; Jiao, Jianbin; Ye, Qixiang

    2017-07-01

    Scene images usually involve semantic correlations, particularly when considering large-scale image data sets. This paper proposes a novel generative image representation, correlated topic vector, to model such semantic correlations. Oriented from the correlated topic model, correlated topic vector intends to naturally utilize the correlations among topics, which are seldom considered in the conventional feature encoding, e.g., Fisher vector, but do exist in scene images. It is expected that the involvement of correlations can increase the discriminative capability of the learned generative model and consequently improve the recognition accuracy. Incorporated with the Fisher kernel method, correlated topic vector inherits the advantages of Fisher vector. The contributions to the topics of visual words have been further employed by incorporating the Fisher kernel framework to indicate the differences among scenes. Combined with the deep convolutional neural network (CNN) features and Gibbs sampling solution, correlated topic vector shows great potential when processing large-scale and complex scene image data sets. Experiments on two scene image data sets demonstrate that correlated topic vector improves significantly the deep CNN features, and outperforms existing Fisher kernel-based features.

  17. Fostering Topic Knowledge: Essential for Academic Writing

    Science.gov (United States)

    Proske, Antje; Kapp, Felix

    2013-01-01

    Several researchers emphasize the role of the writer's topic knowledge for writing. In academic writing topic knowledge is often constructed by studying source texts. One possibility to support that essential phase of the writing process is to provide interactive learning questions which facilitate the construction of an adequate situation…

  18. Advanced topics in the arithmetic of elliptic curves

    CERN Document Server

    Silverman, Joseph H

    1994-01-01

    In the introduction to the first volume of The Arithmetic of Elliptic Curves (Springer-Verlag, 1986), I observed that "the theory of elliptic curves is rich, varied, and amazingly vast," and as a consequence, "many important topics had to be omitted." I included a brief introduction to ten additional topics as an appendix to the first volume, with the tacit understanding that eventually there might be a second volume containing the details. You are now holding that second volume. it turned out that even those ten topics would not fit Unfortunately, into a single book, so I was forced to make some choices. The following material is covered in this book: I. Elliptic and modular functions for the full modular group. II. Elliptic curves with complex multiplication. III. Elliptic surfaces and specialization theorems. IV. Neron models, Kodaira-Neron classification of special fibers, Tate's algorithm, and Ogg's conductor-discriminant formula. V. Tate's theory of q-curves over p-adic fields. VI. Neron's theory of can...

  19. Topical Ranibizumab as a Treatment of Corneal Neovascularization

    Science.gov (United States)

    Ferrari, Giulio; Dastjerdi, Mohammad H.; Okanobo, Andre; Cheng, Sheng-Fu; Amparo, Francisco; Nallasamy, Nambi; Dana, Reza

    2014-01-01

    Purpose To examine the effect of topical ranibizumab on clinically stable corneal neovascularization (NV). Methods This was a prospective, open-label, monocentric, uncontrolled, non-comparative study. Ten eyes of 9 patients with corneal NV received topical ranibizumab (1%) 4 times a day for 3 weeks with a follow-up of 16 weeks. The main corneal neovascularization outcome measures were: neovascular area (NA), the area occupied by the corneal neovessels; vessel caliber (VC), the mean diameter of the corneal neovessels; and invasion area (IA), the fraction of the total cornea area covered by the vessels. This study was conducted at the Massachusetts Eye and Ear Infirmary, Boston, MA, USA. Results Statistically significant decreases in NA (55.3%, P<0.001), which lasted through 16 weeks, and VC (59%, P<0.001), which continued to improve up to week 16, were observed after treatment. No significant decrease was observed in IA (12.3%, P=0.49). There was no statistically significant change in visual acuity or intraocular pressure. No adverse events ascribed to the treatment were noted. Conclusions Topical application of ranibizumab is effective in reducing the severity of corneal NV in the context of established corneal NV, mostly through decrease in VC rather than IA. PMID:23407316

  20. Sky cover from MFRSR observations

    Directory of Open Access Journals (Sweden)

    E. Kassianov

    2011-07-01

    Full Text Available The diffuse all-sky surface irradiances measured at two nearby wavelengths in the visible spectral range and their modeled clear-sky counterparts are the main components of a new method for estimating the fractional sky cover of different cloud types, including cumuli. The performance of this method is illustrated using 1-min resolution data from a ground-based Multi-Filter Rotating Shadowband Radiometer (MFRSR. The MFRSR data are collected at the US Department of Energy Atmospheric Radiation Measurement (ARM Climate Research Facility (ACRF Southern Great Plains (SGP site during the summer of 2007 and represent 13 days with cumuli. Good agreement is obtained between estimated values of the fractional sky cover and those provided by a well-established independent method based on broadband observations.

  1. Covering and Reimbursing Telehealth Services.

    Science.gov (United States)

    Blackman, Kate

    2016-01-01

    Policymakers who are striving to achieve better health care, improved health outcomes and lower costs are considering new strategies and technologies. Telehealth is a tool that uses technology to provide health services remotely, and state leaders are looking to it now more than ever as a way to address workforce gaps and reach underserved patients. Among the challenges facing state lawmakers who are working to introduce or expand telehealth is how to handle covering patients and reimbursing providers.

  2. 76 FR 81806 - Ophthalmic and Topical Dosage Form New Animal Drugs; Ivermectin Topical Solution

    Science.gov (United States)

    2011-12-29

    .... FDA-2011-N-0003] Ophthalmic and Topical Dosage Form New Animal Drugs; Ivermectin Topical Solution... solution of ivermectin. DATES: This rule is effective December 29, 2011. FOR FURTHER INFORMATION CONTACT... ANADA 200-318 for [[Page 81807

  3. Topics in linear optical quantum computation

    Science.gov (United States)

    Glancy, Scott Charles

    This thesis covers several topics in optical quantum computation. A quantum computer is a computational device which is able to manipulate information by performing unitary operations on some physical system whose state can be described as a vector (or mixture of vectors) in a Hilbert space. The basic unit of information, called the qubit, is considered to be a system with two orthogonal states, which are assigned logical values of 0 and 1. Photons make excellent candidates to serve as qubits. They have little interactions with the environment. Many operations can be performed using very simple linear optical devices such as beam splitters and phase shifters. Photons can easily be processed through circuit-like networks. Operations can be performed in very short times. Photons are ideally suited for the long-distance communication of quantum information. The great difficulty in constructing an optical quantum computer is that photons naturally interact weakly with one another. This thesis first gives a brief review of two early approaches to optical quantum computation. It will describe how any discrete unitary operation can be performed using a single photon and a network of beam splitters, and how the Kerr effect can be used to construct a two photon logic gate. Second, this work provides a thorough introduction to the linear optical quantum computer developed by Knill, Laflamme, and Milburn. It then presents this author's results on the reliability of this scheme when implemented using imperfect photon detectors. This author finds that quantum computers of this sort cannot be built using current technology. Third, this dissertation describes a method for constructing a linear optical quantum computer using nearly orthogonal coherent states of light as the qubits. It shows how a universal set of logic operations can be performed, including calculations of the fidelity with which these operations may be accomplished. It discusses methods for reducing and

  4. Topical ganciclovir in the treatment of acute herpetic keratitis

    Directory of Open Access Journals (Sweden)

    Khalid F Tabbara

    2010-08-01

    Full Text Available Khalid F Tabbara1,2,3, Noorjehan Al Balushi11The Eye Center and The Eye Foundation for Research in Ophthalmology, Riyadh, 2Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia; 3The Wilmer Ophthalmological Institute of The Johns Hopkins University School of Medicine, Baltimore, Maryland, USAAbstract: Herpetic keratitis is caused by herpes simplex virus (HSV and is a common cause of corneal blindness. Following a primary ocular herpetic infection, latency of the virus occurs, followed by subsequent recurrences of herpetic keratitis. Such recurrences may lead to structural damage of the cornea. Recurrent herpetic keratitis is a common indication for corneal transplantation. Recurrences of herpetic keratitis in the corneal graft may lead to corneal graft rejection. Several antiviral agents for HSV are available, including the thymidine analogs. Prolonged use of thymidine analogs may lead to toxicity of the ocular surface, including epithelial keratitis, corneal ulcers, follicular conjunctivitis, and punctal occlusions. Availability of topical antiviral agents that are safe and effective in the treatment and prophylaxis of herpetic keratitis is highly desirable. Ganciclovir is a potent inhibitor of members of the herpes virus family. The drug has been used systemically for the treatment of cytomegalovirus (CMV retinitis. Its hematologic toxicity secondary to systemic administration led to its limited use in herpetic infections. On the other hand, topical ganciclovir has been shown to be as safe and effective as acyclovir in the treatment of herpetic epithelial keratitis. Furthermore, topical ganciclovir can reach therapeutic levels in the cornea and aqueous humor following topical application. Several clinical trials have shown that topical ganciclovir 0.15% ophthalmic gel is safe and effective in the treatment and prophylaxis of herpetic epithelial disease. Long-term use of ganciclovir ophthalmic

  5. Nanocrystal: a novel approach to overcome skin barriers for improved topical drug delivery.

    Science.gov (United States)

    Patel, Viral; Sharma, Om Prakash; Mehta, Tejal

    2018-04-01

    Skin is an important route of drug delivery for the treatment of various dermatological conditions. The advent of nanotechnology is paving the roadmaps for topical drug delivery by providing sustained release as well as maintaining a localized effect, outweighing the toxicity concern. Area covered: This review highlighted the morphology of skin, its barrier nature as well as drug penetration pathways after topical application of formulations. The existing methods to improve topical drug delivery, by infringing or permeating the skin barriers, are discussed. This context concretes the foundation to accentuate the need for the development of nanocrystal-based topical formulation. The mechanism of drug release, immediate as well as sustained release, after topical administration of drug nanocrystals is also elaborated. The special emphasis is given on the breakthrough achieved, in topical drug delivery using drug nanocrystals, so far in the plethora of literature, patents, and products, under clinical trial as well as in the market. Expert opinion: The current research on nanocrystals for topical drug delivery is highlighting the breakthroughs achieved so far. The output of these research envisages that topical nanocrystals based formulations can be a novel strategy for the drugs which are facing solubility, bioavailability and toxicity concerns.

  6. Glaucoma: Hot Topics in Pharmacology.

    Science.gov (United States)

    Balendra, Shiama I; Shah, Parth Arvind; Jain, Mishank; Grzybowski, Andrzej; Cordeiro, Maria F

    2017-01-01

    Glaucoma comprises a group of neurodegenerative diseases resulting in retinal ganglion cell death within the optic nerve head. It is projected to affect almost 80 million people worldwide by 2020. The condition's asymptomatic nature translates to over half of glaucoma sufferers being unaware of their condition. By the time of diagnosis, irreversible blindness is likely to have occurred. Prime areas of glaucoma research therefore include identification and optimization of risk factors for the disease, accurate and early diagnostic tools and novel therapeutic methods. The goal of this review was to summarize main areas of latest glaucoma research into risk factors of glaucoma, diagnostic tools and treatments. PubMed was used to search for terms including glaucoma risk factors, glaucoma diagnostics, glaucoma treatment, glaucoma drug delivery and glaucoma IOP. The evidence for risk factors of low CSF pressure, IOP, smoking, vascular risk factors and light toxicity is described. Latest diagnostic and monitoring techniques for glaucoma include SD-OCT, DARC and IOP telemetry. Current and emerging medical and surgical treatments in glaucoma are discussed. Rho kinase inhibitors have the potential to both lower IOP and also provide neuroprotection, several of which are in clinical trials. Several other new medical treatments such as calcium channel blockers and neurotrophic agents also have the capacity to provide neuroprotection. Minimally Invasive Glaucoma Surgery (MIGS) devices provide an improved safety profile compared to traditional trabeculectomy; the latest ab interno and ab externo devices are described. Novel drug delivery methods, including punctual plugs and contact lenses, help overcome the challenges with patient adherence. The ultimate goals are to reduce the individual patient risk factors associated with glaucoma, diagnose the condition early and to find treatments that not only reduce IOP but also reverse neurodegeneration of RGCs. The usage of combinations

  7. Melanoma or Pseudo melanoma Change in a pigmented lesion after application of topical 5-Fluorouracil

    Science.gov (United States)

    2017-10-26

    2. REPORT TYPE 3. DATES COVERED (From - To) 10/26/2017 Poster 10/26/2017-10/29/2017 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Melanoma or Pseudo...melanoma? Change in a pigmented lesion after application of topical 5-Fluorouracil. 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d

  8. Academicians' and Practitioners' Views on the Importance of the Topical Content in the First Auditing Course

    Science.gov (United States)

    Armitage, Jack; Poyzer, Jillian K.

    2010-01-01

    The research question addressed in this study is to compare and identify differences between academics teaching auditing classes and practicing accountants regarding the importance of topics covered in the first university auditing course. This is accomplished by surveying academics and practitioners regarding their perceptions of the importance…

  9. Topics in Finance Part I--Introduction and Stockholder Wealth Maximization

    Science.gov (United States)

    Laux, Judy

    2010-01-01

    The following article represents the first in a series dedicated to presenting students the opportunity to better understand the key theoretical constructs in the introductory financial management course. The current essay offers an introduction to the series and covers the topics of stockholder wealth maximization and its close cousin, agency…

  10. Recent topical research on global, energy, health & medical, and tourism economics, and global software: An overview

    NARCIS (Netherlands)

    C-L. Chang (Chia-Lin); M.J. McAleer (Michael)

    2017-01-01

    textabstractThe paper presents an overview of recent topical research on global, energy, health & medical, and tourism economics, and global software. We have interpreted "global" in the title of the Journal of Reviews on Global Economics to cover contributions that have a global impact on

  11. Recent Topical Research on Global, Energy, Health & Medical, and Tourism Economics, and Global Software

    NARCIS (Netherlands)

    C-L. Chang (Chia-Lin); M.J. McAleer (Michael)

    2017-01-01

    textabstractThe paper presents an overview of recent topical research on global, energy, health & medical, and tourism economics, and global software. We have interpreted “global” in the title of the Journal of Reviews on Global Economics to cover contributions that have a global impact on

  12. A Topic Analysis of ISECON Conference Proceedings from 1982 through 2014

    Science.gov (United States)

    Clark, Jon; Athey, Susan; Plotnicki, Jon; Barnes, Jay

    2016-01-01

    The authors note a distinct shift in topics covered in curricula as well as in conference presentations. This research was undertaken to get a better understanding of what these shifts have been, and determine their magnitude over time. Since ISECON has published its conference proceedings in digital format since 1982, this was a logical source of…

  13. Problematic topic transitions in dysarthric conversation.

    Science.gov (United States)

    Bloch, Steven; Saldert, Charlotta; Ferm, Ulrika

    2015-01-01

    This study examined the nature of topic transition problems associated with acquired progressive dysarthric speech in the everyday conversation of people with motor neurone disease. Using conversation analytic methods, a video collection of five naturally occurring problematic topic transitions was identified, transcribed and analysed. These were extracted from a main collection of over 200 other-initiated repair sequences and a sub-set of 15 problematic topic transition sequences. The sequences were analysed with reference to how the participants both identified and resolved the problems. Analysis revealed that topic transition by people with dysarthria can prove problematic. Conversation partners may find transitions problematic not only because of speech intelligibility but also because of a sequential disjuncture between the dysarthric speech turn and whatever topic has come prior. In addition the treatment of problematic topic transition as a complaint reveals the potential vulnerability of people with dysarthria to judgements of competence. These findings have implications for how dysarthria is conceptualized and how specific actions in conversation, such as topic transition, might be suitable targets for clinical intervention.

  14. Hot topics in tetralogy of Fallot.

    Science.gov (United States)

    Villafañe, Juan; Feinstein, Jeffrey A; Jenkins, Kathy J; Vincent, Robert N; Walsh, Edward P; Dubin, Anne M; Geva, Tal; Towbin, Jeffrey A; Cohen, Meryl S; Fraser, Charles; Dearani, Joseph; Rosenthal, David; Kaufman, Beth; Graham, Thomas P

    2013-12-10

    Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect. We explore "hot topics" to highlight areas of emerging science for clinicians and scientists in moving toward a better understanding of the long-term management of patients with repaired TOF. From a genetic perspective, the etiology of TOF is multifactorial, with a familial recurrence risk of 3%. Cardiac magnetic resonance is the gold standard assessment tool based on its superior imaging of the right ventricular (RV) outflow tract, pulmonary arteries, aorta, and aortopulmonary collaterals, and on its ability to quantify biventricular size and function, pulmonary regurgitation (PR), and myocardial viability. Atrial re-entrant tachycardia will develop in more than 30% of patients, and high-grade ventricular arrhythmias will be seen in about 10% of patients. The overall incidence of sudden cardiac death is estimated at 0.2%/yr. Risk stratification, even with electrophysiologic testing and cardiac magnetic resonance, remains imperfect. Drug therapy has largely been abandoned, and defibrillator placement, despite its high risks for complications and inappropriate discharges, is often recommended for patients at higher risk. Definitive information about optimal surgical strategies for primary repair to preserve RV function, reduce arrhythmia, and optimize functional status is lacking. Post-operative lesions are often amenable to transcatheter intervention. In selected cases, PR may be treated with transcatheter valve insertion. Ongoing surveillance of RV function is a crucial component of clinical assessment. Except for resynchronization with biventricular pacing, no medical therapies have been shown to be effective after RV dysfunction occurs. In patients with significant PR with RV dilation, optimal timing of pulmonary valve replacement remains uncertain, although accepted criteria are emerging. Copyright © 2013 American College of Cardiology Foundation. Published by Elsevier Inc. All

  15. Control of pain with topical plant medicines

    Directory of Open Access Journals (Sweden)

    James David Adams Jr.

    2015-04-01

    Full Text Available Pain is normally treated with oral nonsteroidal anti-inflammatory agents and opioids. These drugs are dangerous and are responsible for many hospitalizations and deaths. It is much safer to use topical preparations made from plants to treat pain, even severe pain. Topical preparations must contain compounds that penetrate the skin, inhibit pain receptors such as transient receptor potential cation channels and cyclooxygenase-2, to relieve pain. Inhibition of pain in the skin disrupts the pain cycle and avoids exposure of internal organs to large amounts of toxic compounds. Use of topical pain relievers has the potential to save many lives, decrease medical costs and improve therapy.

  16. Digital Social Network Mining for Topic Discovery

    Science.gov (United States)

    Moradianzadeh, Pooya; Mohi, Maryam; Sadighi Moshkenani, Mohsen

    Networked computers are expanding more and more around the world, and digital social networks becoming of great importance for many people's work and leisure. This paper mainly focused on discovering the topic of exchanging information in digital social network. In brief, our method is to use a hierarchical dictionary of related topics and words that mapped to a graph. Then, with comparing the extracted keywords from the context of social network with graph nodes, probability of relation between context and desired topics will be computed. This model can be used in many applications such as advertising, viral marketing and high-risk group detection.

  17. Stress shadows - a controversial topic

    Science.gov (United States)

    Lasocki, Stanislaw; Karakostas, Vassilis G.; Papadimitriou, Eletheria E.; Orlecka-Sikora, Beata

    2010-05-01

    the sign of the change though distinctly more in areas of positive than of negative change. In the case of seismicity accompanying underground mining exploitation the coseismic stress changes expressed in terms of the Coulomb failure function are at least of one order smaller than those for earthquakes. Furthermore, they are only a small component of the total stress field variations in mining rockmass, which are mainly controlled by the mining process. Nevertheless, our studies of the induced seismicity in the Rudna mine in the Legnica-Głogow Copper District in Poland showed that the influence of the Coulomb stress changes on locations of subsequent events was statistically significant. We analyzed series of seismic events quantifying the triggering and inhibiting effect by the proportion of events in the series whose locations were consistent with the stress increased and stress decreased zones, respectively. It was found out that more than 60 per-cent of the analyzed seismic events occurred in areas where stress was enhanced due to the occurrence of previous events. The significance of this result was determined by comparing it with 2000 results of the same analysis carried out on the random permutations of the original series of events. The test indicated that the locations in positive stress changes areas were preferred statistically significantly when the stress changes exceeded 0.05 bar. However, no statistically significant inhibiting effect of negative static stress changes, within the considered range of these changes, was ascertained. Here we present details of these two studies and discuss possible reasons behind the negative conclusions on the existence of stress shadows.

  18. Analyses of Research Topics in the Field of Informetrics Based on the Method of Topic Modeling

    OpenAIRE

    Sung-Chien Lin

    2014-01-01

    In this study, we used the approach of topic modeling to uncover the possible structure of research topics in the field of Informetrics, to explore the distribution of the topics over years, and to compare the core journals. In order to infer the structure of the topics in the field, the data of the papers published in the Journal of Informetricsand Scientometrics during 2007 to 2013 are retrieved from the database of the Web of Science as input of the approach of topic modeling. The results ...

  19. "(Un)covering" in the Classroom: Managing Stigma beyond the Closet

    Science.gov (United States)

    Branfman, Jonathan

    2017-01-01

    While many instructors closet stigmatized identities, others "downplay" them--a tactic that sociologist Erving Goffman terms "covering." What are the personal, ethical, and pedagogical costs of covering? What are the gains? How can feminist university instructors cover stigmatized identities without fueling oppressive…

  20. Topic Modeling of Smoking- and Cessation-Related Posts to the American Cancer Society's Cancer Survivor Network (CSN): Implications for Cessation Treatment for Cancer Survivors Who Smoke.

    Science.gov (United States)

    Westmaas, J Lee; McDonald, Bennett R; Portier, Kenneth M

    2017-08-01

    Smoking is a risk factor in at least 18 cancers, and approximately two-thirds of cancer survivors continue smoking following diagnosis. Text mining of survivors' online posts related to smoking and quitting could inform strategies to reduce smoking in this vulnerable population. We identified posts containing smoking/cessation-related keywords from the Cancer Survivors Network (CSN), an online cancer survivor community of 166 000 members and over 468 000 posts since inception. Unsupervised topic model analysis of posts since 2000 using Latent Dirichlet Allocation extracted 70 latent topics which two subject experts inspected for themes based on representative terms. Posterior analysis assessed the distribution of topics within posts, and the range of themes discussed across posts. Less than 1% of posts (n = 3998) contained smoking/cessation-related terms, and covered topics related to cancer diagnoses, treatments, and coping. The most frequent smoking-related topics were quit smoking methods (5.4% of posts), and the environment for quitters (2.9% of posts), such as the stigma associated with being a smoker diagnosed with cancer and lack of empathy experienced compared to nonsmokers. Smoking as a risk factor for one's diagnosis was a primary topic in only 1.7% of smoking/cessation-related posts. The low frequency of smoking/cessation-related posts may be due to expected criticism/stigma for smoking but may also suggests a need for health care providers to address smoking and assist with quitting in the diagnostic and treatment process. Topic model analysis revealed potential barriers that should be addressed in devising clinical or population-level interventions for cancer survivors who smoke. Although smoking is a major risk factor for cancer, little is known about cancer patients' or survivors' views or concerns about smoking and quitting. This study used text mining of posts to an online community of cancer patients and survivors to investigate contexts in which

  1. Corneal Neurotoxicity Due to Topical Benzalkonium Chloride

    OpenAIRE

    Sarkar, Joy; Chaudhary, Shweta; Namavari, Abed; Ozturk, Okan; Chang, Jin-Hong; Yco, Lisette; Sonawane, Snehal; Khanolkar, Vishakha; Hallak, Joelle; Jain, Sandeep

    2012-01-01

    Topical application of benzalkonium chloride (BAK) to the eye causes dose-related corneal neurotoxicity. Corneal inflammation and reduction in aqueous tear production accompany neurotoxicity. Cessation of BAK treatment leads to recovery of corneal nerve density.

  2. 152 TOPICALIZATION AND PASSIVISATION IN THE ENGLISH ...

    African Journals Online (AJOL)

    It is believed that this study will further highlight some of the basic ... The objective of the study is to explore topicalization and passivisation in the English Language ..... Radford, R. Transformational Syntax A Student Guide to Chomsky's ...

  3. Web Enabled DROLS Verity TopicSets

    National Research Council Canada - National Science Library

    Tong, Richard

    1999-01-01

    The focus of this effort has been the design and development of automatically generated TopicSets and HTML pages that provide the basis of the required search and browsing capability for DTIC's Web Enabled DROLS System...

  4. Neutron spectroscopy, nuclear structure, related topics. Abstracts

    International Nuclear Information System (INIS)

    Sukhovoj, A.M.

    1996-01-01

    Neutron spectroscopy, nuclear structure and related topics are considered. P, T-breaking, neutron beta decay, neutron radiative capture and neutron polarizability are discussed. Reaction with fast neutrons, methodical aspect low-energy fission are considered too

  5. Atopic dermatitis: tacrolimus vs. topical corticosteroid use

    African Journals Online (AJOL)

    Atopic dermatitis (AD) is an inflammatory skin disease that is characterised .... effective in the treatment of AD.5. Although ..... original steroid preparations,20 the cost-effectiveness of ... Topical corticosteroids [homepage on the Internet]. c2010.

  6. Gastrointestinal Bleeding: MedlinePlus Health Topic

    Science.gov (United States)

    ... are many possible causes of GI bleeding, including hemorrhoids , peptic ulcers , tears or inflammation in the esophagus, ... blood Show More Show Less Related Health Topics Hemorrhoids Peptic Ulcer National Institutes of Health The primary ...

  7. Birth Weight: MedlinePlus Health Topic

    Science.gov (United States)

    ... growth restriction Large for gestational age (LGA) Neonatal weight gain and nutrition Small for gestational age (SGA) Related Health Topics Fetal Health and Development Premature Babies Uncommon Infant and Newborn Problems National Institutes of Health The primary NIH ...

  8. Systemic and topical antibiotics for chronic rhinosinusitis.

    Science.gov (United States)

    Head, Karen; Chong, Lee Yee; Piromchai, Patorn; Hopkins, Claire; Philpott, Carl; Schilder, Anne G M; Burton, Martin J

    2016-04-26

    This review is one of six looking at the primary medical management options for patients with chronic rhinosinusitis.Chronic rhinosinusitis is common and is characterised by inflammation of the lining of the nose and paranasal sinuses leading to nasal blockage, nasal discharge, facial pressure/pain and loss of sense of smell. The condition can occur with or without nasal polyps. Systemic and topical antibiotics are used with the aim of eliminating infection in the short term (and some to reduce inflammation in the long term), in order to normalise nasal mucus and improve symptoms. To assess the effects of systemic and topical antibiotics in people with chronic rhinosinusitis. The Cochrane ENT Information Specialist searched the Cochrane ENT Trials Register; CENTRAL (2015, Issue 8); MEDLINE; EMBASE; ClinicalTrials.gov; ICTRP and additional sources for published and unpublished trials. The date of the search was 29 September 2015. Randomised controlled trials (RCTs) with a follow-up period of at least three months comparing systemic or topical antibiotic treatment to (a) placebo or (b) no treatment or (c) other pharmacological interventions. We used the standard methodological procedures expected by Cochrane. Our primary outcomes were disease-specific health-related quality of life (HRQL), patient-reported disease severity and the commonest adverse event - gastrointestinal disturbance. Secondary outcomes included general HRQL, endoscopic nasal polyp score, computerised tomography (CT) scan score and the adverse events of suspected allergic reaction (rash or skin irritation) and anaphylaxis or other very serious reactions. We used GRADE to assess the quality of the evidence for each outcome; this is indicated in italics. We included five RCTs (293 participants), all of which compared systemic antibiotics with placebo or another pharmacological intervention.The varying study characteristics made comparison difficult. Four studies recruited only adults and one only

  9. Glossary of atomic terms

    International Nuclear Information System (INIS)

    1982-04-01

    This glossary, containing almost 400 terms, has been compiled to help people outside the atomic energy industry to understand what those inside it are saying. It is not intended to be a definitive dictionary of scientific or technical terms, nor does it aim to cover terms that are in general use in science and technology. A list of about 100 initials and acronyms will be found at the end. (author)

  10. Glossary of atomic terms

    International Nuclear Information System (INIS)

    1980-01-01

    This glossary (of about 400 terms) has been compiled to help people outside the atomic energy industry to understand what those inside it are saying. It is not intended to be a definitive dictionary of scientific or technical terms, nor does it aim to cover terms that are in general use in science and technology. A list of some initials and acronyms is appended. (author)

  11. Constructing topic models of Internet of Things for information processing.

    Science.gov (United States)

    Xin, Jie; Cui, Zhiming; Zhang, Shukui; He, Tianxu; Li, Chunhua; Huang, Haojing

    2014-01-01

    Internet of Things (IoT) is regarded as a remarkable development of the modern information technology. There is abundant digital products data on the IoT, linking with multiple types of objects/entities. Those associated entities carry rich information and usually in the form of query records. Therefore, constructing high quality topic hierarchies that can capture the term distribution of each product record enables us to better understand users' search intent and benefits tasks such as taxonomy construction, recommendation systems, and other communications solutions for the future IoT. In this paper, we propose a novel record entity topic model (RETM) for IoT environment that is associated with a set of entities and records and a Gibbs sampling-based algorithm is proposed to learn the model. We conduct extensive experiments on real-world datasets and compare our approach with existing methods to demonstrate the advantage of our approach.

  12. Constructing Topic Models of Internet of Things for Information Processing

    Science.gov (United States)

    Xin, Jie; Cui, Zhiming; Zhang, Shukui; He, Tianxu; Li, Chunhua; Huang, Haojing

    2014-01-01

    Internet of Things (IoT) is regarded as a remarkable development of the modern information technology. There is abundant digital products data on the IoT, linking with multiple types of objects/entities. Those associated entities carry rich information and usually in the form of query records. Therefore, constructing high quality topic hierarchies that can capture the term distribution of each product record enables us to better understand users' search intent and benefits tasks such as taxonomy construction, recommendation systems, and other communications solutions for the future IoT. In this paper, we propose a novel record entity topic model (RETM) for IoT environment that is associated with a set of entities and records and a Gibbs sampling-based algorithm is proposed to learn the model. We conduct extensive experiments on real-world datasets and compare our approach with existing methods to demonstrate the advantage of our approach. PMID:25110737

  13. Data Mining Thesis Topics in Finland

    OpenAIRE

    Bajo Rouvinen, Ari

    2017-01-01

    The Theseus open repository contains metadata about more than 100,000 thesis publications from the different universities of applied sciences in Finland. Different data mining techniques were applied to the Theseus dataset to build a web application to explore thesis topics and degree programmes using different libraries in Python and JavaScript. Thesis topics were extracted from manually annotated keywords by the authors and curated subjects by the librarians. During the project, the quality...

  14. Topical reports on Louisiana salt domes

    International Nuclear Information System (INIS)

    1983-09-01

    The Institute for Environmental Studies at Louisiana State University conducted research into the potential use of Louisiana salt domes for disposal of nuclear waste material. Topical reports generated in 1981 and 1982 related to Vacherie and Rayburn's domes are compiled and presented, which address palynological studies, tiltmeter monitoring, precise releveling, saline springs, and surface hydrology. The latter two are basically a compilation of references related to these topics. Individual reports are abstracted

  15. Is topical haloperidol a useful glaucoma treatment?

    OpenAIRE

    Lavin, M. J.; Andrews, V.

    1986-01-01

    A randomised, double blind, single dose study of topical haloperidol, a dopamine receptor blocking drug, was performed on 20 healthy volunteers. After its administration a modest reduction in intraocular pressure was recorded over the six-hour study period, but the difference was not significant at the p less than 0.05 level. Although dopamine blocking agents are effective in reducing intraocular pressure in experimental animals, topical haloperidol appears unlikely to be clinically useful in...

  16. Selected topics in e+e- physics

    International Nuclear Information System (INIS)

    Sau Lan Wu

    1981-01-01

    Selected topics of recent experimental results from the high-energy electron-positron storage rings are presented. The topics include some of the tau and charm physics from SPEAR, the upsilon physics from DORIS and CESR, and the γγ physics and quark and gluon physics from the PLUTO and TASSO Collaborations at PETRA. Related data from the JADE and MARK J Collaborations at PETRA are discussed in separated papers at this school. (orig.)

  17. Topical Melatonin for Treatment of Androgenetic Alopecia

    OpenAIRE

    Fischer, Tobias W; Tr?eb, Ralph M; H?nggi, Gabriella; Innocenti, Marcello; Elsner, Peter

    2012-01-01

    Background: In the search for alternative agents to oral finasteride and topical minoxidil for the treatment of androgenetic alopecia (AGA), melatonin, a potent antioxidant and growth modulator, was identified as a promising candidate based on in vitro and in vivo studies. Materials and Methods: One pharmacodynamic study on topical application of melatonin and four clinical pre-post studies were performed in patients with androgenetic alopecia or general hair loss and evaluated by standardise...

  18. Immunomodulation and safety of topical calcineurin inhibitors for the treatment of atopic dermatitis.

    Science.gov (United States)

    Hultsch, Thomas; Kapp, Alexander; Spergel, Jonathan

    2005-01-01

    Atopic dermatitis (AD) is a chronic or chronically relapsing inflammatory skin condition that primarily affects children. Topical corticosteroids have been the mainstay of treatment since the late 1950s. While providing excellent short-term efficacy, topical corticosteroid usage is limited by potential adverse effects, including impairment of the function and viability of Langerhans cells/dendritic cells. The recently introduced topical calcineurin inhibitors pimecrolimus cream 1% (Elidel) and tacrolimus ointment 0.03 and 0.1% (Protopic) exhibit a more selective mechanism of action and do not affect Langerhans cells/dendritic cells. For the immune system of young children 'learning' to mount a balanced Th1/Th2 response, this selective effect has particular benefits. In clinical experience, topical calcineurin inhibitors have been shown to be a safe and effective alternative to topical corticosteroids in almost 7 million patients (>5 million on pimecrolimus; >1.7 million on tacrolimus). Topical pimecrolimus is primarily used in children with mild and moderate AD, whereas tacrolimus is used preferentially in more severe cases. None of the topical calcineurin inhibitors have been associated with systemic immunosuppression-related malignancies known to occur following long-term sustained systemic immunosuppression with oral immunosuppressants (e.g., tacrolimus, cyclosporine A, and corticosteroids) in transplant patients. Preclinical and clinical data suggest a greater skin selectivity and larger safety margin for topical pimecrolimus. (c) 2005 S. Karger AG, Basel

  19. Efficacy of terbinafine compared to lanoconazole and luliconazole in the topical treatment of dermatophytosis in a guinea pig model.

    Science.gov (United States)

    Ghannoum, M A; Long, L; Kim, H G; Cirino, A J; Miller, A R; Mallefet, P

    2010-05-01

    The in vivo efficacy of terbinafine was compared to lanoconazole and luliconazole in the topical treatment of dermatophytosis caused by Trichophyton mentagrophytes using a guinea pig model. Topical antifungal treatment commenced three days post-infection, and each agent was applied once daily for seven consecutive days. Upon completion of the treatment period, evaluations of clinical and mycological efficacies were performed, as was scanning electron microscopy (SEM) analyses. Data showed that while all tested antifungals demonstrated significant mycological efficacy in terms of eradicating the fungi over untreated control, terbinafine and luliconazole showed superior clinical efficacy compared to lanoconazole (P-values Terbinafine demonstrated the highest clinical percent efficacy. SEM analysis revealed hairs from terbinafine and lanoconazole-treated animals had near complete clearance of fungi, while samples from luliconazole-treated animals were covered with debris and few conidia. This study demonstrates that, in general, terbinafine possessed similar efficacy to lanoconazole and luliconazole in the treatment of dermatophytosis. Terbinafine tended to have superior clinical efficacy compared to the azoles tested, although this difference was not statistically significant against luliconazole. This apparent superiority may be due to the fungicidal activity of terbinafine compared to the fungistatic effect of the other two drugs.

  20. Efeitos a curto prazo de "stents" não recobertos e recobertos com politetrafluoroetileno em aorta de suínos: um modelo experimental Short-term effects of polytetrafluoroethylene covered and uncovered metallic "stents" in pig aorta: an experimental model

    Directory of Open Access Journals (Sweden)

    Marco Aurélio Grüdtner

    2004-04-01

    -expandable uncovered metallic stent. On group III animals (n=10 an auto-expandable stent covered with PTFE was inserted. After four weeks the animals were killed, the specimens were harvested and the intimal thickening was quantified by morphometric analysis. RESULTS: In the comparison among groups I, II and III referring to intimal, medial area and intimal index, it was not observed statistically significant variation. Differences were identified among groups referring to luminal proximal (p=0,036 and distal areas (p=0,044. Through multiple comparison tests for Kruskal-Wallis it was identified a difference between groups I and II. However, when these variables were controlled by weigh factor (luminal area/weigh relation, this difference was not observed anymore. CONCLUSION: In this short term study, the PTFE covering is not associated to further intimal thickening besides that promoted by the metallic mesh in large arteries and in high flow conditions.

  1. Topical steroid addiction in atopic dermatitis

    Directory of Open Access Journals (Sweden)

    Fukaya M

    2014-10-01

    Full Text Available Mototsugu Fukaya,1 Kenji Sato,2 Mitsuko Sato,3 Hajime Kimata,4 Shigeki Fujisawa,5 Haruhiko Dozono,6 Jun Yoshizawa,7 Satoko Minaguchi8 1Tsurumai Kouen Clinic, Nagoya, 2Department of Dermatology, Hannan Chuo Hospital, Osaka, 3Sato Pediatric Clinic, Osaka, 4Kimata Hajime Clinic, Osaka, 5Fujisawa Dermatology Clinic, Tokyo, 6Dozono Medical House, Kagoshima, 7Yoshizawa Dermatology Clinic, Yokohama, 8Department of Dermatology, Kounosu Kyousei Hospital, Saitama, Japan Abstract: The American Academy of Dermatology published a new guideline regarding topical therapy in atopic dermatitis in May 2014. Although topical steroid addiction or red burning skin syndrome had been mentioned as possible side effects of topical steroids in a 2006 review article in the Journal of the American Academy of Dermatology, no statement was made regarding this illness in the new guidelines. This suggests that there are still controversies regarding this illness. Here, we describe the clinical features of topical steroid addiction or red burning skin syndrome, based on the treatment of many cases of the illness. Because there have been few articles in the medical literature regarding this illness, the description in this article will be of some benefit to better understand the illness and to spur discussion regarding topical steroid addiction or red burning skin syndrome. Keywords: topical steroid addiction, atopic dermatitis, red burning skin syndrome, rebound, corticosteroid, eczema

  2. Land cover mapping of Greater Mesoamerica using MODIS data

    Science.gov (United States)

    Giri, Chandra; Jenkins, Clinton N.

    2005-01-01

    A new land cover database of Greater Mesoamerica has been prepared using moderate resolution imaging spectroradiometer (MODIS, 500 m resolution) satellite data. Daily surface reflectance MODIS data and a suite of ancillary data were used in preparing the database by employing a decision tree classification approach. The new land cover data are an improvement over traditional advanced very high resolution radiometer (AVHRR) based land cover data in terms of both spatial and thematic details. The dominant land cover type in Greater Mesoamerica is forest (39%), followed by shrubland (30%) and cropland (22%). Country analysis shows forest as the dominant land cover type in Belize (62%), Cost Rica (52%), Guatemala (53%), Honduras (56%), Nicaragua (53%), and Panama (48%), cropland as the dominant land cover type in El Salvador (60.5%), and shrubland as the dominant land cover type in Mexico (37%). A three-step approach was used to assess the quality of the classified land cover data: (i) qualitative assessment provided good insight in identifying and correcting gross errors; (ii) correlation analysis of MODIS- and Landsat-derived land cover data revealed strong positive association for forest (r2 = 0.88), shrubland (r2 = 0.75), and cropland (r2 = 0.97) but weak positive association for grassland (r2 = 0.26); and (iii) an error matrix generated using unseen training data provided an overall accuracy of 77.3% with a Kappa coefficient of 0.73608. Overall, MODIS 500 m data and the methodology used were found to be quite useful for broad-scale land cover mapping of Greater Mesoamerica.

  3. Towards realistic Holocene land cover scenarios: integration of archaeological, palynological and geomorphological records and comparison to global land cover scenarios.

    Science.gov (United States)

    De Brue, Hanne; Verstraeten, Gert; Broothaerts, Nils; Notebaert, Bastiaan

    2016-04-01

    Accurate and spatially explicit landscape reconstructions for distinct time periods in human history are essential for the quantification of the effect of anthropogenic land cover changes on, e.g., global biogeochemical cycles, ecology, and geomorphic processes, and to improve our understanding of interaction between humans and the environment in general. A long-term perspective covering Mid and Late Holocene land use changes is recommended in this context, as it provides a baseline to evaluate human impact in more recent periods. Previous efforts to assess the evolution and intensity of agricultural land cover in past centuries or millennia have predominantly focused on palynological records. An increasing number of quantitative techniques has been developed during the last two decades to transfer palynological data to land cover estimates. However, these techniques have to deal with equifinality issues and, furthermore, do not sufficiently allow to reconstruct spatial patterns of past land cover. On the other hand, several continental and global databases of historical anthropogenic land cover changes based on estimates of global population and the required agricultural land per capita have been developed in the past decennium. However, at such long temporal and spatial scales, reconstruction of past anthropogenic land cover intensities and spatial patterns necessarily involves many uncertainties and assumptions as well. Here, we present a novel approach that combines archaeological, palynological and geomorphological data for the Dijle catchment in the central Belgium Loess Belt in order to arrive at more realistic Holocene land cover histories. Multiple land cover scenarios (> 60.000) are constructed using probabilistic rules and used as input into a sediment delivery model (WaTEM/SEDEM). Model outcomes are confronted with a detailed geomorphic dataset on Holocene sediment fluxes and with REVEALS based estimates of vegetation cover using palynological data from

  4. Enhanced Cover Assessment Project:Soil Manipulation and Revegetation Tests

    Energy Technology Data Exchange (ETDEWEB)

    Waugh, W. Joseph [Navarro Research and Engineering, Inc.; Albright, Dr. Bill [Desert Research Inst. (DRI), Reno, NV (United States); Benson, Dr. Craig [University of Wisconsin-Madison

    2014-02-01

    The U.S. Department of Energy Office of Legacy Management is evaluating methods to enhance natural changes that are essentially converting conventional disposal cell covers for uranium mill tailings into water balance covers. Conventional covers rely on a layer of compacted clayey soil to limit exhalation of radon gas and percolation of rainwater. Water balance covers rely on a less compacted soil “sponge” to store rainwater, and on soil evaporation and plant transpiration (evapotranspiration) to remove stored water and thereby limit percolation. Over time, natural soil-forming and ecological processes are changing conventional covers by increasing hydraulic conductivity, loosening compaction, and increasing evapotranspiration. The rock armor on conventional covers creates a favorable habitat for vegetation by slowing soil evaporation, increasing soil water storage, and trapping dust and organic matter, thereby providing the water and nutrients needed for plant germination, survival, and sustainable transpiration. Goals and Objectives Our overall goal is to determine if allowing or enhancing these natural changes could improve cover performance and reduce maintenance costs over the long term. This test pad study focuses on cover soil hydrology and ecology. Companion studies are evaluating effects of natural and enhanced changes in covers on radon attenuation, erosion, and biointrusion. We constructed a test cover at the Grand Junction disposal site to evaluate soil manipulation and revegetation methods. The engineering design, construction, and properties of the test cover match the upper three layers of the nearby disposal cell cover: a 1-foot armoring of rock riprap, a 6-inch bedding layer of coarse sand and gravel, and a 2-foot protection layer of compacted fine soil. The test cover does not have a radon barrier—cover enhancement tests leave the radon barrier intact. We tested furrowing and ripping as means for creating depressions parallel to the slope

  5. Incorporating Topic Assignment Constraint and Topic Correlation Limitation into Clinical Goal Discovering for Clinical Pathway Mining

    Directory of Open Access Journals (Sweden)

    Xiao Xu

    2017-01-01

    Full Text Available Clinical pathways are widely used around the world for providing quality medical treatment and controlling healthcare cost. However, the expert-designed clinical pathways can hardly deal with the variances among hospitals and patients. It calls for more dynamic and adaptive process, which is derived from various clinical data. Topic-based clinical pathway mining is an effective approach to discover a concise process model. Through this approach, the latent topics found by latent Dirichlet allocation (LDA represent the clinical goals. And process mining methods are used to extract the temporal relations between these topics. However, the topic quality is usually not desirable due to the low performance of the LDA in clinical data. In this paper, we incorporate topic assignment constraint and topic correlation limitation into the LDA to enhance the ability of discovering high-quality topics. Two real-world datasets are used to evaluate the proposed method. The results show that the topics discovered by our method are with higher coherence, informativeness, and coverage than the original LDA. These quality topics are suitable to represent the clinical goals. Also, we illustrate that our method is effective in generating a comprehensive topic-based clinical pathway model.

  6. Selected topics in the quantum theory of solids: collective excitations and linear response

    International Nuclear Information System (INIS)

    Balakrishnan, V.

    1977-08-01

    This report is based on the lecture notes of a course given at the Department of Physics, Indian Institute of Technology, Madras, during the period January-April 1976 for M.Sc. students. The emphasis is on the concept of elementary excitations in many-body systems, and on the technique of linear response theory. Various topics are covered in 7 sections. The second section following the introductory section is on 'second quantization' and includes discussion on creation and destruction operators, multiparticle states, time-dependent operators etc. Section 3 deals with the 'electron gas' and includes discussion on non-interacting Fermi gas, Coulomb interaction and exchange energy, the two-electron correlation function etc. Section 4 deals with the dielectric response analysis of the electron gas and includes discussion on Coulomb interaction in terms of density fluctuations, self-consistent field dielectric function etc. In section 5 the 'linear response theory' is explained. The Liouville operator, Boltzmann's superposition integral, dispersion relations etc. are explained. Quasiparticles and plasmous are discussed in the Section 6. Section 7 deals with 'lattice dynamics and phonons'. In the last section 8, spin waves are explained. The Heisenberg exchange hamiltonian, Green Function for noninteracting magnons etc. are discussed. (author)

  7. Strategies of persuasion in offers to participate in cancer clinical trials I: Topic placement and topic framing.

    Science.gov (United States)

    Barton, Ellen; Eggly, Susan; Winckles, Andrew; Albrecht, Terrance L

    2014-01-01

    Clinical trials are the gold standard in medical research evaluating new treatments in cancer care; however, in the United States, too few patients enroll in trials, especially patients from minority groups. Offering patients the option of a clinical trial is an ethically-charged communicative event for oncologists. One particularly vexed ethical issue is the use of persuasion in trial offers. Based on a corpus of 22 oncology encounters with Caucasian-American (n = 11) and African-American (n = 11) patients, this discourse analysis describes oncologists' use of two persuasive strategies related to the linguistic structure of trial offers: topic placement and topic framing. Findings are presented in total and by patient race, and discussed in terms of whether these strategies may constitute ethical or unethical persuasion, particularly with respect to the ethical issue of undue influence and the social issue of underrepresentation of minorities in cancer clinical trials.

  8. Cover crops support ecological intensification of arable cropping systems

    Science.gov (United States)

    Wittwer, Raphaël A.; Dorn, Brigitte; Jossi, Werner; van der Heijden, Marcel G. A.

    2017-02-01

    A major challenge for agriculture is to enhance productivity with minimum impact on the environment. Several studies indicate that cover crops could replace anthropogenic inputs and enhance crop productivity. However, so far, it is unclear if cover crop effects vary between different cropping systems, and direct comparisons among major arable production systems are rare. Here we compared the short-term effects of various cover crops on crop yield, nitrogen uptake, and weed infestation in four arable production systems (conventional cropping with intensive tillage and no-tillage; organic cropping with intensive tillage and reduced tillage). We hypothesized that cover cropping effects increase with decreasing management intensity. Our study demonstrated that cover crop effects on crop yield were highest in the organic system with reduced tillage (+24%), intermediate in the organic system with tillage (+13%) and in the conventional system with no tillage (+8%) and lowest in the conventional system with tillage (+2%). Our results indicate that cover crops are essential to maintaining a certain yield level when soil tillage intensity is reduced (e.g. under conservation agriculture), or when production is converted to organic agriculture. Thus, the inclusion of cover crops provides additional opportunities to increase the yield of lower intensity production systems and contribute to ecological intensification.

  9. Ground cover in old-growth forests of the central hardwood region

    Science.gov (United States)

    Martin A. Spetich; Stephen R. Shifley; George R. Parker; Felix, Jr. Ponder

    1997-01-01

    Differences in ground cover (percent cover of litter, percent cover of vegetation and litter weight) in old-growth forests across this region are not well understood. We initiated a long-term study in a three-state region to enhance knowledge in this area. We present baseline results for ground cover and compare these data across productivity regions. Thirty 0.25-ac (0...

  10. Assessing winter cover crop nutrient uptake efficiency using a water quality simulation model

    OpenAIRE

    Yeo, I.-Y.; Lee, S.; Sadeghi, A. M.; Beeson, P. C.; Hively, W. D.; McCarty, G. W.; Lang, M. W.

    2014-01-01

    Winter cover crops are an effective conservation management practice with potential to improve water quality. Throughout the Chesapeake Bay watershed (CBW), which is located in the mid-Atlantic US, winter cover crop use has been emphasized, and federal and state cost-share programs are available to farmers to subsidize the cost of cover crop establishment. The objective of this study was to assess the long-term effect of planting winter cover crops to improve water quality a...

  11. LDA-Based Unified Topic Modeling for Similar TV User Grouping and TV Program Recommendation.

    Science.gov (United States)

    Pyo, Shinjee; Kim, Eunhui; Kim, Munchurl

    2015-08-01

    prediction precision was 79.6%. Also, we showed the superiority of our proposed model in terms of both topic modeling performance and recommendation performance compared to two related topic models such as polylingual topic model and bilingual topic model.

  12. International topical meeting TOPSEAL 2006. Transactions

    International Nuclear Information System (INIS)

    2006-01-01

    From 17-20 September 2006, over 100 nuclear scientists and engineers from across Europe, Canada, the USA, Japan and Korea converged on the Olkiluoto Information Centre in Finland to attend TOPSEAL 2006. This international topical meeting dedicated to the subject of radioactive waste management was organised by the European Nuclear Society (ENS) in co-operation with the Finnish Nuclear Society (ATS) and the OECD/NEA. The conference was hosted by TVO, Finland's largest power utility and POSIVA, a daughter company of TVO and the country's number one radioactive waste management specialist. The main message that emerged from the conference is that a range of technological solutions exist and are currently being developed and applied across Europe - and beyond - to ensure the safe and efficient long term management of all categories of nuclear waste and spent fuel. Against the background of the nuclear revival, more and more countries are now looking closely at all available options. The TOPSEAL 2006 agenda centred upon four main sessions devoted respectively to: international perspectives on radioactive waste management; research, development and demonstration of waste storage and disposal; existing experiences with low and intermediate level radioactive waste and deep geological and near surface repositories. The conference concluded with a panel discussion entitled Future Challenges in radioactive Waste Management and a visit of the waste management facilities in Olkiluoto. Among the many issues discussed by TOPSEAL delegates was EU policy and legislation related to waste management, deep underground repositories, near surface storage, the experimental modelling of safety barriers, radiation shielding and research funding. Research and development programmes, benchmarking and long term strategies in several countries were also presented and discussed at length. A recurring theme that underpinned the discussions was the need to increase public understanding and

  13. Some current engineering topics in nuclear power plant components

    International Nuclear Information System (INIS)

    Amana, M.

    1977-01-01

    An analysis based on the principle of fracture mechanics, is presented for several engineering problems occuring in nuclear power plant components. The specific problems covered are: underclad cracking; stress corrosion cracking; cracks in HAZ of nozzle weld; feedwater nozzle corner crack; shift of transition temperature due to neutron irradiation; LWR local-ECC thermal shock experiment; and design and material selection of RPV in terms of fracture mechanics. (B.R.H.)

  14. 45 CFR 1211.1-5 - Matters not covered.

    Science.gov (United States)

    2010-10-01

    ... directly affect the volunteer's work situation or the terms and conditions of service as defined in § 1211... SERVICE VOLUNTEER GRIEVANCE PROCEDURES § 1211.1-5 Matters not covered. Matters not within the definition... excluded by this part: (a) The establishment of a volunteer project, its continuance or discontinuance, the...

  15. Medical support of children’s sports: Topical problems

    Directory of Open Access Journals (Sweden)

    L. A. Balykova

    2017-01-01

    Full Text Available The paper discusses the most topical issues of medical support of children and adolescents engaged in physical exercises and sports. Much attention is paid to different views on the etiology, pathogenesis, diagnosis, and principles of therapy of pathological transformation of the heart in child athletes. The problem of sudden cardiac death in sports and the possibility of a relationship between connective tissue dysplasia and its development are touched upon. Electrocardiographic and morphological criteria for cardiac maladaptation in athletes are discussed. The problem of early and accessible diagnosis and Russia’s tactics for the diagnosis of health changes in athletes and approaches to their prevention and treatment are covered. Different ways to prevent the pathological transformation of the cardiovascular system in athletes and sudden cardiac death as its extreme manifestation are discussed.

  16. Topics in algebra and analysis preparing for the mathematical olympiad

    CERN Document Server

    Bulajich Manfrino, Radmila; Valdez Delgado, Rogelio

    2015-01-01

    The techniques presented here are useful for solving mathematical contest problems in algebra and analysis. Most of the examples and exercises that appear in the book originate from mathematical Olympiad competitions around the world. In the first four chapters the authors cover material for competitions at high school level. The level advances with the chapters. The topics explored include polynomials, functional equations, sequences and an elementary treatment of complex numbers. The final chapters provide a comprehensive list of problems posed at national and international contests in recent years, and solutions to all exercises and problems presented in the book. It helps students in preparing for national and international mathematical contests form high school level to more advanced competitions and will also be useful for their first year of mathematical studies at the university. It will be of interest to teachers in college and university level, and trainers of the mathematical Olympiads.

  17. Topics in statistical data analysis for high-energy physics

    International Nuclear Information System (INIS)

    Cowan, G.

    2011-01-01

    These lectures concert two topics that are becoming increasingly important in the analysis of high-energy physics data: Bayesian statistics and multivariate methods. In the Bayesian approach, we extend the interpretation of probability not only to cover the frequency of repeatable outcomes but also to include a degree of belief. In this way we are able to associate probability with a hypothesis and thus to answer directly questions that cannot be addressed easily with traditional frequentist methods. In multivariate analysis, we try to exploit as much information as possible from the characteristics that we measure for each event to distinguish between event types. In particular we will look at a method that has gained popularity in high-energy physics in recent years: the boosted decision tree. Finally, we give a brief sketch of how multivariate methods may be applied in a search for a new signal process. (author)

  18. Statistical evaluation of diagnostic performance topics in ROC analysis

    CERN Document Server

    Zou, Kelly H; Bandos, Andriy I; Ohno-Machado, Lucila; Rockette, Howard E

    2016-01-01

    Statistical evaluation of diagnostic performance in general and Receiver Operating Characteristic (ROC) analysis in particular are important for assessing the performance of medical tests and statistical classifiers, as well as for evaluating predictive models or algorithms. This book presents innovative approaches in ROC analysis, which are relevant to a wide variety of applications, including medical imaging, cancer research, epidemiology, and bioinformatics. Statistical Evaluation of Diagnostic Performance: Topics in ROC Analysis covers areas including monotone-transformation techniques in parametric ROC analysis, ROC methods for combined and pooled biomarkers, Bayesian hierarchical transformation models, sequential designs and inferences in the ROC setting, predictive modeling, multireader ROC analysis, and free-response ROC (FROC) methodology. The book is suitable for graduate-level students and researchers in statistics, biostatistics, epidemiology, public health, biomedical engineering, radiology, medi...

  19. OpenMPI and ExxonMobil Topics

    Energy Technology Data Exchange (ETDEWEB)

    Hjelm, Nathan Thomas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pritchard, Howard Porter [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-09-09

    These are a series of slides for a presentation for ExxonMobil's visit to Los Alamos National Laboratory. Topics covered are: Open MPI - The Release Story, MPI-3 RMA in Open MPI, MPI dynamic process management and Open MPI, and new options with CLE 6. Open MPI RMA features are: since v2.0.0 full support for the MPI-3.1 specification, support for non-contiguous datatypes, support for direct use of the RDMA capabilities of high performance networks (Cray Gemini/Aries, Infiniband), starting in v2.1.0 will have support for using network atomic operations for MPI_Fetch_and_op and MPI_Compare_and_swap, tested with MPI_THREAD_MULTIPLE.

  20. Proceedings of the topical meeting on reactivity initiated accidents (RIA)

    International Nuclear Information System (INIS)

    2003-01-01

    The topical meeting was devoted to RIA fuel acceptance criteria, in particular to the fuel fragmentation enthalpy limit and the PCMI failure enthalpy limit in relation to high burnup fuel. In total 50 participants attended. Research and industry organisations from France, Finland, Germany, Hungary, Japan, the Russian Federation, Sweden, the United Kingdom and the USA including the Swiss regulatory body, HSK, and the Halden reactor project, presented 16 papers in all. The papers covered three main areas: 'best estimate' core calculations for RIA energy deposition in high burnup fuels, the technical background of current and new RIA fuel safety criteria, and ongoing RIA experimental programmes. A number of open issues were identified, whose resolution is expected from ongoing and planned national and international experimental programmes