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Sample records for tephrosia toxicaria pers

  1. Chemical and biological study of Tephrosia toxicaria Pers; Estudo quimico e biologico de Tephrosia toxicaria Pers

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    Vasconcelos, Jackson Nunes e; Lima, Jefferson Queiroz; Lemos, Telma Leda Gomes de; Oliveira, Maria da Conceicao Ferreira de; Almeida, Maria Mozarina Beserra; Andrade-Neto, Manoel; Mafezoli, Jair; Arriaga, Angela Martha Campos; Braz-Filho, Raimundo [Universidade Federal do Ceara (UFC), Fortaleza, CE (Brazil). Dept. de Quimica Organica e Inorganica]. E-mail: angelamcarriaga@yahoo.com.br; Santiago, Gilvandete Maria Pinheiro [Universidade Federal do Ceara (UFC), Fortaleza, CE (Brazil). Faculdade de Farmacia, Odontologia e Enfermagem. Dept. de Farmacia

    2009-07-01

    The ethanol extracts from leaves, stems, pods and roots were assayed against the third instar Aedes aegypti larvae and the highest activity was observed in the roots extracts (LC{sub 50} 47.86 ppm). This extract was submitted to partition with hexane, chloroform, ethyl acetate and methanol. The respective fractions were bioassayed and the best larvicidal activities were identified in the hexane (LC{sub 50} 23.99 ppm) and chloroform (LC{sub 50} 13.80 ppm) fractions. Antioxidant activity (DDPH method) was observed in the ethanol extract (IC{sub 50} 276 {mu}g/mL) from roots of T. toxicaria. Fractions from this extract were also tested and the highest antioxidant activity (IC{sub 50} 89 {mu}g/mL) was found in the methanol fraction. The flavonoids iso-obovatin (1), obovatin (2), 6a,12a-dehydro-{beta}-toxicarol (3), 6a,12a-dehydro-{alpha}-toxicarol (4) and {alpha}-toxicarol (5) were isolated and bioassayed against A. aegypti. The flavonoid 5 showed the best larvicidal activity (LC{sub 50} 24.55 ppm). The antioxidant activity of 2 was investigated and showed IC{sub 50} 3.370 {mu}g/ml. The antioxidant and larvicidal activities of Tephrosia toxicaria are reported for the first time. (author)

  2. Rotenoids from Tephrosia toxicaria with larvicidal activity against Aedes aegypti, the main vector of dengue fever

    International Nuclear Information System (INIS)

    Vasconcelos, Jackson Nunes e; Santiago, Gilvandete Maria Pinheiro; Lima, Jefferson Queiroz; Arriaga, Angela Martha Campos

    2012-01-01

    In the search for new larvicides from plants, we have investigated the potential activity of the rotenoids deguelin (1), 12a-hydroxy-a-toxicarol (2) and tephrosin (3), isolated from the bioactive ethanol extract of roots of Tephrosia toxicaria Pers., against Aedes aegypti, the main vector of dengue. The absolute configuration of these compounds was determined by circular dichroism (CD) spectra. The LC50 values of the compounds evaluated justify the potential of T. toxicaria as a new natural larvicide. (author)

  3. Antinociceptive Effect of Tephrosia sinapou Extract in the Acetic Acid, Phenyl-p-benzoquinone, Formalin, and Complete Freund’s Adjuvant Models of Overt Pain-Like Behavior in Mice

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    Renata M. Martinez

    2016-01-01

    Full Text Available Tephrosia toxicaria, which is currently known as Tephrosia sinapou (Buc’hoz A. Chev. (Fabaceae, is a source of compounds such as flavonoids. T. sinapou has been used in Amazonian countries traditional medicine to alleviate pain and inflammation. The purpose of this study was to evaluate the analgesic effects of T. sinapou ethyl acetate extract in overt pain-like behavior models in mice by using writhing response and flinching/licking tests. We demonstrated in this study that T. sinapou extract inhibited, in a dose (1–100 mg/kg dependent manner, acetic acid- and phenyl-p-benzoquinone- (PBQ- induced writhing response. Furthermore, it was active via intraperitoneal, subcutaneous, and peroral routes of administration. T. sinapou extract also inhibited formalin- and complete Freund’s adjuvant- (CFA- induced flinching/licking at 100 mg/kg dose. In conclusion, these findings demonstrate that T. sinapou ethyl acetate extract reduces inflammatory pain in the acetic acid, PBQ, formalin, and CFA models of overt pain-like behavior. Therefore, the potential of analgesic activity of T. sinapou indicates that it deserves further investigation.

  4. In Vitro effect of the ethanolic extract of Tephrosia Vogelii on Rhipicephalus Sanguineus in Abomey-Calavi

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    Dougnon Tossou Jacques

    2015-04-01

    Full Text Available Objectives: Ticks are vectors of several diseases, of which many are zoonosis transmissible to humans. The use of Tephrosia leafs’ extract as a low cost acaricide is spreading among farmers in central Kenya. Materials and Methods: The present study’s aim is to inventory endogenous control methods against dogs’ ticks among which Rhipicephalus sanguineus, in the Municipality of Abomey-Calavi. From September to October 2013, a survey was made on forty randomly selected breeders and ticks samples were collected on forty dogs. The web platform, www.epicollect.net, was used for the survey. In total, 77.5% (n=40 of examined dogs were infested with ticks Results: Three species of ticks were identified: Rhipicephalus sanguineus, Haemaphysalis leachi, and Amblyomma variegatum. They were found on 77.5%, 17.5%, and 15% of examined dogs, respectively. The numerical abundance of the three species was 87.06%, 11.9%, and 1.03%, respectively. The average number of ticks per animal was 16.83±5.04, 2.3±1.64, and 0.2±0.08 for Rhipicephalus sanguineus, Haemaphysalis leachi, and Amblyomma variegatum, respectively. Farmers used manual diptank (67.5%, plant ash (37.5%, petroleum (12.5%, motor oil (2.50 %, and sea water (7.5% to fight against ticks. Conclusions: The phytochemical screening of the leafy stem’s powder of Tephrosia vogelii revealed the presence of catechol tannins, saponins, sugars, leuco-anthocyanins, polyterpenes, and sterols. A 100% larval mortality was observed at the concentration of 20% the ethanolic extract of the leafy stem of Tephrosia vogelii. The LC50 of this ethanolic extract against Rhipicephalus sanguineus larvae was equal to 2.6%.

  5. Phytochemical analysis of Tephrosia vogelii (fish poison bean ...

    African Journals Online (AJOL)

    This work was carried out to determine the chemical constituents of Tephrosia vogelii (Fish poison bean), in order to test the extracts of the plant for use as fish tranquilizer. Fresh samples of T. vogelii were collected separately, air-dried for 21 days and oven-dried at 60o C for 3-4 hours to constant weight. The dried samples ...

  6. Toxicity and antipyretic studies of the crude extract of Tephrosia ...

    African Journals Online (AJOL)

    Toxicity and antipyretic studies of the crude extract of Tephrosia bractiolata leaves. MOA Onaolapo, HC Nzelibe, AO Aduadi, JO Ayo. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · http://dx.doi.org/10.4314/jopat.v9i1.48589.

  7. Utilization of Tephrosia vogelii in controlling ticks in dairy cows by ...

    African Journals Online (AJOL)

    The study sought to evaluate the effectiveness of Tephrosia vogelii in controlling ticks on dairy cows among small-scale dairy farmers in Mashonaland Central Province of Zimbabwe. T. vogelii treatment concentrations and Triatix D acaricide dip were randomly administered to 40 dairy cows. The experiment was carried out ...

  8. Ethno-medical and veterinary uses of Tephrosia vogelii hook. F.: a ...

    African Journals Online (AJOL)

    All parts of Tephrosia vogelii Hook. f. (Fabaceae) is used in tropical Africa for numerous ethno-medical and traditional veterinary practices. The leaf is ichthyotoxic and has been used as insecticide, rodenticide and anthelminthic. It has also been used as abortifacient and to induce menses. The leaf macerate is purgative and ...

  9. A kaempferol triglycoside from Tephrosia preussii Taub. (Fabaceae).

    Science.gov (United States)

    Mba Nguekeu, Yves Martial; Awouafack, Maurice Ducret; Tane, Pierre; Nguedia Lando, Marius Roch; Kodama, Takeshi; Morita, Hiroyuki

    2017-11-01

    A phytochemical investigation of the MeOH extract of twigs and leaves of Tephrosia preussi was carried out to give a new kaempferol triglycoside, named tephrokaempferoside (1), together with five known compounds: tephrosin (2), betulinic acid (3), lupeol (4), β-sitosterol (5) and 3-O-β-d-glucopyranoside of β-sitosterol (6). The structure of the new compound was characterised by analyses of NMR (1D and 2D) and MS data, and chemical conversion. Tephrokaempferoside (1) had weak antibacterial activity against Klebsiella pneumoniae with an MIC value of 150 μg/mL.

  10. Managing Tephrosia mulch and fertilizer to enhance coffee productivity on smallholder farms in the Eastern African Highlands

    NARCIS (Netherlands)

    Bucagu, C.; Vanlauwe, B.; Giller, K.E.

    2013-01-01

    In Maraba, Southwest Rwanda, coffee productivity is constrained by poor soil fertility and lack of organic mulch. We investigated the potential to produce mulch by growing Tephrosia vogelii either intercropped with smallholder coffee or in arable fields o

  11. Six month-duration Tephrosia vogelii Hook.f. and Tithonia diversifolia (Hemsl.). A.Gray planted-fallows for improving maize production in Kenya

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    Rutunga, V.; Karanja, N.K.; Gachene, C.K.K.

    2008-01-01

    An experiment including planted Tephrosia vogelii and Tithonia diversifolia fallow species and natural fallow was conducted at Maseno, Kenya, for assessing whether these fallows grown on a nutrient depleted land could produce sufficient green manure in six month period, whether their biomass

  12. NUTRITIVE VALUE OF TEPHROSIA CANDIDA SEED IN WEST AFRICAN DWARF GOATS

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    Olaniyi BABAYEMI

    2007-07-01

    Full Text Available Groundnut-cake (GNC, Soybean-meal (SBM and cottonseed-cake (CSC are expensive protein sources for ruminants. This study examined the feeding value of unconventional protein source of Tephrosia candida seed (TCS in WAD goats. Four diets were formulated using GNC, SBM, CSC and TCS protein sources and fed to WAD goats to monitor intake, digestibility and nitrogen utilization. Effects of feeding the diets as supplements on weight gain of grazing goats were also investigated. Results showed the dry matter intake (DMI of the concentrate made from the conventional protein were not significantly different (mean = 101.0 g/d but depressed in TCS diets (66.11 g/d. Crude protein intake (CPI, g/d from TCS (16.67 was higher (P < 0.05 than that of GNC (16.55 but was inferior to the CPI of both CSC (25.56 and SBM (19.72 diets. Intake of NDF (38.21 – 51.08 g/d and ADF (17.84 – 28.97 varied (P < 0.05 and followed the trend observed for CPI. Apparent digestibility of CP (% was higher (P < 0.05 in TCS (63.05 than values for both the SBM (58.2 and CSC (42.79 diets, but not the GNC (63.78. The best digested NDF (53.36% and ADF (53.93% were from GNC and TCS diets respectively. N-balance (g/d and retention (% compared favourably in TCS (1.42 and 53.2 with those of SBM (1.69 and 51.9 and GNC (1.41 and 53.2 but were significantly least (P < 0.05 in CSC diet (1.34 and 32.6. Weight gain of grazing goats was highest (27.38 g/day and lowest (7.74 g/day in goats fed TCS and SBM respectively. Tephrosia candida seed can be used as a protein source ingredient as performance of goats on it was comparable to those of expensive GNC, SBM and CSC.

  13. In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea

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    Rizvi Tania Shamim

    2018-06-01

    Full Text Available The present study investigates the potential role of medicinal plants Citrullus colocynthis and Tephrosia apollinea in ameliorating the oxidative stress developed during the generation of reactive oxygen species. Organic extracts of different organs (leaf, stem and root of these medicinal plants obtained in n-hexane, chloroform, n-butanol and water were assayed for radical scavenging, total antioxidant capacity, anti-lipid peroxidation and reduced glutathione. The total phenolic content (TPC of both selected medicinal plants was also evaluated. The results indicated that extracts of T. apollinea leaf, stem and root have higher TPC compared to those of C. colocynthis. Similarly, the results of the present study revealed higher bioactivity of C. colocynthis than that of T. apollinea in various antioxidant assays. Various plant parts of each plant were also compared.

  14. Amendment of Tephrosia Improved Fallows with Inorganic Fertilizers Improves Soil Chemical Properties, N Uptake, and Maize Yield in Malawi

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    Maggie G. Munthali

    2014-01-01

    Full Text Available Maize production in Malawi is limited mainly by low soil N and P. Improved fallows of N-fixing legumes such as Tephrosia and Sesbania offer options for improving soil fertility particularly N supply. The interactions of Tephrosia fallows and inorganic fertilizers on soil properties, N uptake, and maize yields were evaluated at Chitedze Research Station in Malawi. The results indicated that the level of organic matter and pH increased in all the treatments except for the control. Total N remained almost unchanged while available P decreased in all plots amended with T. vogelii but increased in T. candida plots where inorganic P was applied. Exchangeable K increased in all the plots irrespective of the type of amendment. The interaction of N and P fertilizers with T. vogelii fallows significantly increased the grain yield. The treatment that received 45 kg N ha−1 and 20 kg P ha−1 produced significantly higher grain yields (6.8 t ha−1 than all the other treatments except where 68 kg N ha−1 and 30 kg P ha−1 were applied which gave 6.5 t ha−1 of maize grain. T. candida fallows alone or in combination with N and P fertilizers did not significantly affect grain yield. However, T. candida fallows alone can raise maize grain yield by 300% over the no-input control. Based on these results we conclude that high quality residues such as T. candida and T. vogelii can be used as sources of nutrients to improve crop yields and soil fertility in N-limited soils. However, inorganic P fertilizer is needed due to the low soil available P levels.

  15. Effect of X-rays on germination of some wild papilionaceous seeds

    International Nuclear Information System (INIS)

    Chaghtai, S.A.; Khan, S.S.; Sultan, Suman

    1978-01-01

    Dry seeds of Aeschynomene indica Linn., Alysicarpus rugosus, Desmodium gangeticum (Linn.) DC., three species of Indigofera Tephrosia purpurea (Linn.) Pers. and Zorniagibbosa were irradiated with 1500r dose of X-rays for breaking their dormancy. Whereas none of the seeds of Alysicarpus rugosus, Indigo fera enneaphylla, I.linifolia and Zornia gibbosa could germinate. 23%, 10%, 3% and 2% germination was recorded for the seeds of Indigofera hirsuta sansu Baker, Tephrosia purpurea Aeschynomene indica and Desmodium gangeticum respectively. (author)

  16. Acute and subacute oral toxicity evaluation of Tephrosia purpurea extract in rodents

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    Talib Hussain

    2012-04-01

    Full Text Available Objective: To evaluate the acute and subacute toxicity of 50% ethanolic extract of Tephrosia purpurea (T. purpurea in rodents. Methods: The acute toxicity test was conducted in Swiss albino mice. The extract of T. purpurea was administrated in single doses of 50, 300 and 2000 mg/ kg and observed for behavioral changes and mortality, if any. In subacute toxicity study, Wistar rats of either sex were administered two doses of T. purpurea i.e., 200 and 400 mg/kg (One-tenth and one-fifth of the maximum tolerated dose, p.o. for 4 weeks. During 28 days of treatment, rats were observed weekly for any change in their body weight, food and water intake. At the end of 28 days, rats were sacrificed for hematological, biochemical and histopathology study. Results: In the acute toxicity study, T. purpurea was found to be well tolerated upto 2 000 mg/kg, produced neither mortality nor changes in behavior in mice. In subacute toxicity study, T. purpurea at dose level of 200 and 400 mg/kg did not produce any significant difference in their body weight, food and water intake when compared to vehicle treated rats. It also showed no significant alteration in hematological and biochemical parameters in experimental groups of rats apart from a decrease in aspartate transaminase, alanine transaminase and alkaline phosphate content at the dose of 400 mg/kg. Histopathological study revealed normal architecture of kidney and liver of T. purpurea treated rats. Conclusions: These results demonstrated that there is a wide margin of safety for the therapeutic use of T. purpurea and further corroborated the traditional use of this extract as an anti hepatocarcinogenic agent

  17. Determination of flavonoids, polyphenols and antioxidant activity of Tephrosia purpurea: a seasonal study.

    Science.gov (United States)

    Pandey, Madan Mohan; Khatoon, Sayyada; Rastogi, Subha; Rawat, Ajay Kumar Singh

    2016-11-01

    Tephrosia purpurea (Linn · ) Pers. is widely used in traditional medicine to treat liver disorders, febrile attacks, enlargement and obstruction of liver, spleen, and kidney. In the present study, investigations were carried out to determine the seasonal impact on the content of flavonoid glycosides and on antioxidant activities so as to identify the optimal time of harvesting. The plant materials were collected in different seasons during 2013-2014. Air-dried, powdered plant materials were extracted with 95% ethanol and ethanol: water (1:1) by ultrasound-assisted extraction process. Their chemical composition in terms of total polyphenol and flavonoid contents (TPCs and TFCs) was determined using modified colorimetric Folin-Ciocalteu method and aluminum chloride colorimetric assay respectively. To determine the in vitro antioxidant activity, diphenyl-picryl hydrazyl (DPPH) radical-scavenging assay and total antioxidant capacity by phosphomolybdate antioxidant assay were carried out. High-performance liquid chromatography (HPLC)/photo-diode array (PDA) analysis was used to quantify the flavonoid glycosides in the samples collected in different seasons. Correlation studies were also carried out between antioxidant activities and TPCs. The highest TPC and TFC were found to be in the 95% ethanolic extract of the August sample and the lowest in the 50% hydro-alcoholic extract of the plant sample collected in winter season. It was observed that in both the assays used to determine the antioxidant activity, the 95% ethanolic extracts in all the seasons showed a higher activity than their respective 50% hydro-alcoholic extracts with an increase in activity as we go from cold to hot to rainy seasons. Based on correlation analysis, DPPH radical-scavenging activities as well as the spectrophotometrically measured phosphomolybdenum complex were also strongly correlated with TPC of the extracts. The most abundant flavonoid glycoside was quercetin-3-O-rhamnoglucoside in all

  18. Gangguan fisiologi dan biokimia Crocidolomia pavonana (F. (Lepidoptera: Crambidae akibat perlakuan ekstrak campuran Tephrosia vogelli dan Piper aduncum

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    Eka Chandra Lina

    2016-02-01

    Full Text Available Plant extracts have been known to cause physiological and biochemical interferences against insect, such as feeding inhibitor, food assimilation, and changes on activity of cytochrome b5 and cytochrome P450. This study was carried out to examine the effect of the extracts mixture of Tephrosia vogeliiand : Piper aduncum (1 : 5 on the physiology of Crocidolomia pavonana (F. as well as extract of P. aduncum on biochemical of C. pavonana. The study showed that larvae of C. pavonana was experiencing a feeding inhibition until 94.82% after treated with extracts mixture on concentration 0.06% or equivalent to LC95. However, larvae treated with extracts mixture on LC25 and LC50 only experienced a relative growth disorders as a result of intrinsic toxicity of extracts mixture which enters into the body of insects. Insect adaptation to toxic plant compounds indicated by an increase in the digestibility of larvae approximately 11.11%. Furthermore, detoxification mechanism by larvae against active compounds of P. aduncum occured and shown by an increase of oxidative enzyme activity of cytochrome b5 and cytochrome P450, in in vivo and in vitro compared to control. This study provides an information about mode of action of extracts mixture of T. vogelii and P. aduncum (1 : 5 on larvae of C. pavonana and detoxification mechanism by larvae due to extract of P. aduncum 

  19. Larvicidal, antimicrobial and brine shrimp activities of extracts from Cissampelos mucronata and Tephrosia villosa from coast region, Tanzania.

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    Nondo, Ramadhani S O; Mbwambo, Zakaria H; Kidukuli, Abdul W; Innocent, Ester M; Mihale, Matobola J; Erasto, Paul; Moshi, Mainen J

    2011-04-23

    The leaves and roots of Cissampelos mucronata A. Rich (Menispermaceae) are widely used in the tropics and subtropics to manage various ailments such as gastro-intestinal complaints, menstrual problems, venereal diseases and malaria. In the Coast region, Tanzania, roots are used to treat wounds due to extraction of jigger. Leaves of Tephrosia villosa (L) Pers (Leguminosae) are reported to be used in the treatment of diabetes mellitus in India. In this study, extracts from the roots and aerial parts of C. mucronata and extracts from leaves, fruits, twigs and roots of T. villosa were evaluated for larvicidal activity, brine shrimps toxicity and antimicrobial activity. Powdered materials from C. mucronata were extracted sequentially by dichloromethane followed by ethanol while materials from T.villosa were extracted by ethanol only. The extracts obtained were evaluated for larvicidal activity using Culex quinquefasciatus Say larvae, cytotoxicity using brine shrimp larvae and antimicrobial activity using bacteria and fungi. Extracts from aerial parts of C. Mucronata exhibited antibacterial activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Vibrio cholera, Bacillus anthracis, Streptococcus faecalis and antifungal activity against Candida albicans and Cryptococcus neoformans. They exhibited very low toxicity to brine shrimps and had no larvicidal activity. The root extracts exhibited good larvicidal activity but weak antimicrobial activity. The root dichloromethane extracts from C. mucronata was found to be more toxic with an LC50 value of 59.608 μg/mL while ethanolic extracts from root were not toxic with LC50>100 μg/mL). Ethanol extracts from fruits and roots of T. villosa were found to be very toxic with LC50 values of 9.690 μg/mL and 4.511 μg/mL, respectively, while, ethanol extracts from leaves and twigs of T. villosa were found to be non toxic (LC50>100 μg/mL). These results support the use of C. mucronata in

  20. Larvicidal, antimicrobial and brine shrimp activities of extracts from Cissampelos mucronata and Tephrosia villosa from coast region, Tanzania

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    Erasto Paul

    2011-04-01

    Full Text Available Abstract Background The leaves and roots of Cissampelos mucronata A. Rich (Menispermaceae are widely used in the tropics and subtropics to manage various ailments such as gastro-intestinal complaints, menstrual problems, venereal diseases and malaria. In the Coast region, Tanzania, roots are used to treat wounds due to extraction of jigger. Leaves of Tephrosia villosa (L Pers (Leguminosae are reported to be used in the treatment of diabetes mellitus in India. In this study, extracts from the roots and aerial parts of C. mucronata and extracts from leaves, fruits, twigs and roots of T. villosa were evaluated for larvicidal activity, brine shrimps toxicity and antimicrobial activity. Methods Powdered materials from C. mucronata were extracted sequentially by dichloromethane followed by ethanol while materials from T.villosa were extracted by ethanol only. The extracts obtained were evaluated for larvicidal activity using Culex quinquefasciatus Say larvae, cytotoxicity using brine shrimp larvae and antimicrobial activity using bacteria and fungi. Results Extracts from aerial parts of C. Mucronata exhibited antibacterial activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Vibrio cholera, Bacillus anthracis, Streptococcus faecalis and antifungal activity against Candida albicans and Cryptococcus neoformans. They exhibited very low toxicity to brine shrimps and had no larvicidal activity. The root extracts exhibited good larvicidal activity but weak antimicrobial activity. The root dichloromethane extracts from C. mucronata was found to be more toxic with an LC50 value of 59.608 μg/mL while ethanolic extracts from root were not toxic with LC50>100 μg/mL. Ethanol extracts from fruits and roots of T. villosa were found to be very toxic with LC50 values of 9.690 μg/mL and 4.511 μg/mL, respectively, while, ethanol extracts from leaves and twigs of T. villosa were found to be non toxic (LC50>100

  1. Exploiting the Complementarity between Dereplication and Computer-Assisted Structure Elucidation for the Chemical Profiling of Natural Cosmetic Ingredients: Tephrosia purpurea as a Case Study.

    Science.gov (United States)

    Hubert, Jane; Chollet, Sébastien; Purson, Sylvain; Reynaud, Romain; Harakat, Dominique; Martinez, Agathe; Nuzillard, Jean-Marc; Renault, Jean-Hugues

    2015-07-24

    The aqueous-ethanolic extract of Tephrosia purpurea seeds is currently exploited in the cosmetic industry as a natural ingredient of skin lotions. The aim of this study was to chemically characterize this ingredient by combining centrifugal partition extraction (CPE) as a fractionation tool with two complementary identification approaches involving dereplication and computer-assisted structure elucidation. Following two rapid fractionations of the crude extract (2 g), seven major compounds namely, caffeic acid, quercetin-3-O-rutinoside, ethyl galactoside, ciceritol, stachyose, saccharose, and citric acid, were unambiguously identified within the CPE-generated simplified mixtures by a recently developed (13)C NMR-based dereplication method. The structures of four additional compounds, patuletin-3-O-rutinoside, kaempferol-3-O-rutinoside, guaiacylglycerol 8-vanillic acid ether, and 2-methyl-2-glucopyranosyloxypropanoic acid, were automatically elucidated by using the Logic for Structure Determination program based on the interpretation of 2D NMR (HSQC, HMBC, and COSY) connectivity data. As more than 80% of the crude extract mass was characterized without need for tedious and labor-intensive multistep purification procedures, the identification tools involved in this work constitute a promising strategy for an efficient and time-saving chemical profiling of natural extracts.

  2. Download this PDF file

    African Journals Online (AJOL)

    appropriate for the 7-oxo form and the revision, on the basis of spectroscopic data, of the structure of praecansone A to 7-OXO-9-methoxy chalcone (2) has been published (3). In a recent investigation (4) of the seed-pods of Tephrosia pumila (Lam.) Pers. we reported the occurrence of praecansone A as the major flavonoid.

  3. Cocoa agroforestry is less resilient to sub-optimal and extreme climate than cocoa in full sun.

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    Abdulai, Issaka; Vaast, Philippe; Hoffmann, Munir P; Asare, Richard; Jassogne, Laurence; Van Asten, Piet; Rötter, Reimund P; Graefe, Sophie

    2018-01-01

    Cocoa agroforestry is perceived as potential adaptation strategy to sub-optimal or adverse environmental conditions such as drought. We tested this strategy over wet, dry and extremely dry periods comparing cocoa in full sun with agroforestry systems: shaded by (i) a leguminous tree species, Albizia ferruginea and (ii) Antiaris toxicaria, the most common shade tree species in the region. We monitored micro-climate, sap flux density, throughfall, and soil water content from November 2014 to March 2016 at the forest-savannah transition zone of Ghana with climate and drought events during the study period serving as proxy for projected future climatic conditions in marginal cocoa cultivation areas of West Africa. Combined transpiration of cocoa and shade trees was significantly higher than cocoa in full sun during wet and dry periods. During wet period, transpiration rate of cocoa plants shaded by A. ferruginea was significantly lower than cocoa under A. toxicaria and full sun. During the extreme drought of 2015/16, all cocoa plants under A. ferruginea died. Cocoa plants under A. toxicaria suffered 77% mortality and massive stress with significantly reduced sap flux density of 115 g cm -2  day -1 , whereas cocoa in full sun maintained higher sap flux density of 170 g cm -2  day -1 . Moreover, cocoa sap flux recovery after the extreme drought was significantly higher in full sun (163 g cm -2  day -1 ) than under A. toxicaria (37 g cm -2  day -1 ). Soil water content in full sun was higher than in shaded systems suggesting that cocoa mortality in the shaded systems was linked to strong competition for soil water. The present results have major implications for cocoa cultivation under climate change. Promoting shade cocoa agroforestry as drought resilient system especially under climate change needs to be carefully reconsidered as shade tree species such as the recommended leguminous A. ferruginea constitute major risk to cocoa functioning under

  4. Tree legumes in medium-term fallows: Nz fixation, nitrate recovery ...

    African Journals Online (AJOL)

    Legume effects on the fixation of atmospheric N and nitrate recovery were determined in a sub-humid, bi-modal rainfall system. Fallows improved with sesbania (Sesbania sesban) and tephrosia (Tephrosia vogellii) produced more biomass and fixed more N than those fallows improved with pigeonpea (Cajanus cajan) or ...

  5. Behavioural Responses of Heterobranchus longifilis Juveniles. Val (Pisces: 1840 Exposed to Freeze–dried Bark Extract of Tephrosia vogelii as an Anaesthetic

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    S.G. Solomon

    2014-03-01

    Full Text Available This study evaluates the anaesthetic properties of freeze-dried leaf extract of Tephrosia vogelii on the African catfish Heterobranchus longifilis juveniles. Experimental fish of Mean weight 115.00 were obtained from River Benue at Makurdi, Nigeria and acclimatized at the hatchery of University of Agriculture Makurdi for two weeks. Four H. longifilis were selected randomly for both control and treatment groups. Each treatment fish was weighed and injected intramuscularly 0.05ml of the extract at concentrations of 0.01, 0.02, 0.03, 0.04, 0.05 and 0.06g/l using a 2ml heparinized syringe. The result showed that H. longifilis in treatment group passed sequentially through the first three stages of anaesthesia but could not attain total loss of equilibrium (stage 4 of anaesthesia. The result showed that treatment group of fishes passed sequentially through the first three stages of anaesthesia but could not attain total loss of equilibrium (stage 4 of anaesthsia. Behavioural responses included mucus secretion, slow and erratic swimming, excrement discharge, increase in opercular beat rate, strong retention of reflex action, partial loss of equilibrium and colour change. The induction time showed a declining pattern with increasing concentration of the extract in the treatment levels with significant differences (P0.05. The most effective concentration was 0.06g/l with an induction time of 32.00±1.76 seconds and a recovery time of 182.00±3.46 minutes. The result of this study revealed that the freeze-dried bark extract of T. vogelii can be used as a tranquilizer for transporting fish over average distances, biopsy and morphological evaluation.

  6. Nutritive value and qualitative assessment of secondary compounds in seeds of eight tropical browse, shrub and pulse legumes.

    Science.gov (United States)

    Babayemi, O J; Demeyer, D; Fievez, V

    2004-01-01

    Seeds of four tropical multipurpose trees (Albizia saman, Albizia lebbeck, Albizia rhizonse, Leucaena leucocephala), two shrubs (Tephrosia candida, Tephrosia bracteolata) and two pulse legume (Lablab purpureus, Canavalia ensiformis) were chemically analysed for dry matter (DM), ash, crude protein (CP), neutral detergent fibre (NDF) and ether extract (EE). Qualitative evaluation of secondary metabolites (saponins, phenols, steroids, and alkaloids) was elucidated. The DM, ash, CP, NDF and EE ranged between 88.9-93.6 %, 3.0-5.4 %, 24.8-38.2 %, 22.1-46.9 % and 2.0-17.0 % respectively. All seed species contained at least one group of secondary plant metabolites and steroids were common to all except C. ensiformis that was not implicated for any. A. lebbeck and A. rhizonse showed low saponin content. Indications for water soluble tannins were reported for L. leucocephala while the two species of Tephrosia contained flavonoids or condensed tannins. The study suggested the potentials of the legumes seed species as a feed source for ruminants.

  7. Impact of fishing with Tephrosia candida (Fabaceae) on diversity and abundance of fish in the streams at the boundary of Sinharaja Man and Biosphere Forest Reserve, Sri Lanka.

    Science.gov (United States)

    Epa, Udaya Priyantha Kankanamge; Mohotti, Chamari Ruvandika Waniga Chinthamanie

    2016-09-01

    Local communities in some Asian, African and American countries, use plant toxins in fish poisoning for fishing activities; however, the effects of this practice on the particular wild fish assemblages is unknown. This study was conducted with the aim to investigate the effects of fish poisoning using Tephrosia candida, on freshwater fish diversity and abundance in streams at the boundary of the World Natural Heritage site, Sinharaja Forest Reserve, Sri Lanka. A total of seven field trips were undertaken on a bimonthly basis, from May 2013 to June 2014. We surveyed five streams with similar environmental and climatological conditions at the boundary of Sinharaja forest. We selected three streams with active fish poisoning practices as treatments, and two streams with no fish poisoning as controls. Physico-chemical parameters and flow rate of water in selected streams were also measured at bimonthly intervals. Fish were sampled by electrofishing and nets in three randomly selected confined locations (6 x 2 m stretch) along every stream. Fish species were identified, their abundances were recorded, and Shannon-Weiner diversity index was calculated for each stream. Streams were clustered based on the Bray-Curtis similarity matrix for fish composition and abundance. Physico-chemical parameters of water were not significantly different among streams (P > 0.05). A total of 15 fish species belonging to four different orders Cypriniformes, Cyprinodontiformes, Perciformes and Siluriformes were collected; nine species (60 %) were endemic, and six (40 %) were native species. From these, 13 fish species were recorded in streams with no poisoning, while five species were recorded in streams where poisoning was practiced. Four endemic and one native fish species were locally extinct in streams where fish poisoning was active. Fish abundance was significantly higher in control streams (32-39/m2) when compared to treatment streams (5-9/m2) (P fish poisoning with T. candida may

  8. How to mix per-flight and per-passenger based airport charges

    NARCIS (Netherlands)

    Czerny, A.I.; Zhang, A.

    2015-01-01

    This paper investigates the questions of why carriers advocate for higher per-passenger airport charges and lower per-flight charges, and whether and when this proposal is welfare-enhancing. Specifically, the paper compares the optimal mix of per-flight and per-passenger based airport charges from

  9. Hearing Office Dispositions Per ALJ Per Day Rate Ranking Report

    Data.gov (United States)

    Social Security Administration — A ranking of ODAR hearing offices by the average number of hearings dispositions per ALJ per day. The average shown will be a combined average for all ALJs working...

  10. Laboratory observations on the larvicidal efficacy of three plant species against mosquito vectors of malaria, dengue/dengue hemorrhagic fever (DF/DHF) and lymphatic filariasis in the semi-arid desert.

    Science.gov (United States)

    Bansal, S K; Singh, Karam V; Sharma, Sapna; Sherwani, M R K

    2012-05-01

    Comparative larvicidal efficacy of aqueous and organic solvent extracts from seeds, leaves and flowers of three desert plants viz. Calotropis procera (Aiton), Tephrosia purpurea (L.) Pers. and Prosopis juliflora (Sw.) DC. was evaluated against Anopheles stephensi (Liston), Aedes aegypti (Linnaeus) and Culex quinquefasciatus (Say). For this purpose larvae of all the three mosquito species were reared in the laboratory and studies carried out on late 3rd or early 4th instars using standard WHO technique. Based on concentration mortality data 24 and 48 hr LC50and LC90 values along with their 95% fiducial limits, regression equation, chi-square (chi2)/ heterogeneity of the response were determined by log probit regression analysis. Experiments were carried out with different solvent extracts of seeds of C. procera which revealed that methanol (24 hr LC50: 127.2, 194.8, 361.0) and acetone (229.9, 368.1,193.0 mg l(-1)) extracts were more effective with the three mosquito species, respectively. Petroleum ether extract was effective only on An. stephensi while aqueous extracts were not effective at all with any of the mosquito species (mortality juliflora were 74.9, 63.2 and 47.0 and 96.2,128.1 and 118.8 mg l(-1) for the above three mosquito species, respectively. Experiments carried out up to 500 mg l-(1) with leaves (T. purpurea) and seeds (P. juliflora) extracts show only up to 10-30% mortality indicating that active larvicidal principle may be present only in the seeds of Tephrosia and leaves of Prosopis. In general, anophelines were found more susceptible than the culicines to the plant derived derivatives. More studies are being carried outon some other desert plants found in this arid region. The study would be of great importance while formulating vector control strategy based on alternative plant based insecticides in this semi-arid region.

  11. Comparing the cost-per-QALYs gained and cost-per-DALYs averted literatures.

    Science.gov (United States)

    Neumann, Peter J; Anderson, Jordan E; Panzer, Ari D; Pope, Elle F; D'Cruz, Brittany N; Kim, David D; Cohen, Joshua T

    2018-01-18

    Background : We examined the similarities and differences between studies using two common metrics used in cost-effectiveness analyses (CEAs): cost per quality-adjusted life years (QALYs) gained and cost per disability-adjusted life year (DALY) averted. Methods : We used the Tufts Medical Center CEA Registry, which contains English-language cost-per-QALY gained studies, and  Global Cost-Effectiveness Analysis (GHCEA) Registry, which contains cost-per-DALY averted studies. We examined study characteristics including intervention type, sponsor, country, and primary disease, and also analysed the number of CEAs versus disease burden estimates for major diseases and conditions across three geographic regions. Results : We identified 6,438 cost-per-QALY and 543 cost-per-DALY studies published through 2016 and observed rapid growth in publication rates for both literatures. Cost-per-QALY studies were most likely to examine pharmaceuticals and interventions in high-income countries. Cost-per-DALY studies predominantly focused on infectious disease interventions and interventions in low and lower-middle income countries. We found discrepancies in the number of published CEAs for certain diseases and conditions in certain regions, suggesting "under-studied" areas (e.g., cardiovascular disease in Southeast Asia, East Asia, and Oceania and "overstudied" areas (e.g., HIV in Sub Saharan Africa) relative to disease burden in those regions. Conclusions : The number of cost-per QALY and cost-per-DALY analyses has grown rapidly with applications to diverse interventions and diseases.  Discrepancies between the number of published studies and disease burden suggest funding opportunities for future cost-effectiveness research.

  12. Discovery and Innovation - Vol 17 (2005)

    African Journals Online (AJOL)

    The larvicidal efficacy of Tephrosia nyikensis Bak subsp. victoriensis Gellet and Brummit crude leaf extract on Anopheles mosquitoes · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. FME Wanjala, RA Oriedo, DMS Karanja, 56-59. http://dx.doi.org/10.4314/dai.v17i1.15688 ...

  13. AuBr3-catalyzed azidation of per-O-acetylated and per-O-benzoylated sugars.

    Science.gov (United States)

    Rajput, Jayashree; Hotha, Srinivas; Vangala, Madhuri

    2018-01-01

    Herein we report, for the first time, the successful anomeric azidation of per- O -acetylated and per- O -benzoylated sugars by catalytic amounts of oxophilic AuBr 3 in good to excellent yields. The method is applicable to a wide range of easily accessible per- O -acetylated and per- O -benzoylated sugars. While reaction with per- O -acetylated and per- O -benzoylated monosaccharides was complete within 1-3 h at room temperature, the per- O -benzoylated disaccharides needed 2-3 h of heating at 55 °C.

  14. Medicare hospital spending per patient (Medicare Spending per Beneficiary) – Additional Decimal Places

    Data.gov (United States)

    U.S. Department of Health & Human Services — The "Medicare hospital spending per patient (Medicare Spending per Beneficiary)" measure shows whether Medicare spends more, less or about the same per Medicare...

  15. Effectiveness of 3 per cent boric acid in 70 per cent alcohol versus 1 per cent clotrimazole solution in otomycosis patients: a randomised, controlled trial.

    Science.gov (United States)

    Romsaithong, S; Tomanakan, K; Tangsawad, W; Thanaviratananich, S

    2016-09-01

    To compare the clinical effectiveness and adverse events for 3 per cent boric acid in 70 per cent alcohol versus 1 per cent clotrimazole solution in the treatment of otomycosis. A total of 120 otomycosis patients were randomly assigned to receive either 1 per cent clotrimazole solution (intervention group) or 3 per cent boric acid in 70 per cent alcohol (control group) at the Khon Kaen Hospital ENT out-patient department. Treatment effectiveness was determined based on the otomicroscopic absence of fungus one week after therapy, following a single application of treatment. After 1 week of treatment, there were data for 109 participants, 54 in the clotrimazole group and 55 in the boric acid group. The absolute difference in cure rates between 1 per cent clotrimazole solution and 3 per cent boric acid in 70 per cent alcohol was 17.9 per cent (95 per cent confidence interval, 2.3 to 33.5; p = 0.028) and the number needed to treat was 6 (95 per cent confidence interval, 3.0 to 43.4). Adverse events for the two agents were comparable. One per cent clotrimazole solution is more effective than 3 per cent boric acid in 70 per cent alcohol for otomycosis treatment.

  16. Species of Concern (SOC) on Department of Defense Installations

    Science.gov (United States)

    2002-07-15

    ARISTIDA STRICTA; DRY, UPLAND FLAT, FILTERED LIGHT; WITH BAPTISIA CINEREA, VIOLA PEDATA, DALEA PINNATA.* SUBPOP A=PINE/SCRUB OAK SANDHILL; FEW SCATTERED...DIOSPYROS VIRG., GAYLUSSACIA DUMOSA, EPIGAEA REPENS, ANDROPOGON SP., BAPTISIA TINCT., TEPHROSIA VIRG., VACCINIUM CRASS., LESPEDEZA SP., DALEA PINNATA...ADENOCAULON BICOLOR , PHACELIA NEMORALIS, CAREX HENDERSONII. CIRSIUM VULGARE COMMON WHERE DISTURBED.* Cedar-hemlock forest on lower slopes of logged

  17. App per l’infanzia: linee guida per una progettazione efficace

    Directory of Open Access Journals (Sweden)

    Silvia Carbotti

    2015-04-01

    Full Text Available I bambini sono affascinati dai tablet e dai dispositivi mobili di ultima generazione. Allo stesso modo si trovano in una fase della vita in cui iniziano a formare preferenze e competenze così come ad esprimere le proprie emozioni e sensazioni attraverso la parola. Questo articolo descrive le strategie per la creazione di applicazioni (app per bambini che siano non solo divertenti ma anche efficaci per esperienze significative che li coinvolgano a livello cognitivo ed emotivo. Quando si disegnano app rivolte ai bambini occorre ricordare che i più piccoli non hanno ancora chiaro come dovrebbe funzionare una specifica tecnologia ma si stanno formando un’opinione a riguardo. Diventa dunque necessario considerare alcuni principi di interaction e visual design affinché l’esperienza vissuta con il tablet incontri bisogni e competenze.

  18. Diurnal rhythmicity of the clock genes Per1 and Per2 in the rat ovary.

    Science.gov (United States)

    Fahrenkrug, Jan; Georg, Birgitte; Hannibal, Jens; Hindersson, Peter; Gräs, Søren

    2006-08-01

    Circadian rhythms are generated by endogenous clocks in the central brain oscillator, the suprachiasmatic nucleus, and peripheral tissues. The molecular basis for the circadian clock consists of a number of genes and proteins that form transcriptional/translational feedback loops. In the mammalian gonads, clock genes have been reported in the testes, but the expression pattern is developmental rather than circadian. Here we investigated the daily expression of the two core clock genes, Per1 and Per2, in the rat ovary using real-time RT-PCR, in situ hybridization histochemistry, and immunohistochemistry. Both Per1 and Per2 mRNA displayed a statistically significant rhythmic oscillation in the ovary with a period of 24 h in: 1) a group of rats during proestrus and estrus under 12-h light,12-h dark cycles; 2) a second group of rats representing a mixture of all 4 d of the estrous cycle under 12-h light,12-h dark conditions; and 3) a third group of rats representing a mixture of all 4 d of estrous cycle during continuous darkness. Per1 mRNA was low at Zeitgeber time 0-2 and peaked at Zeitgeber time 12-14, whereas Per2 mRNA was delayed by approximately 4 h relative to Per1. By in situ hybridization histochemistry, Per mRNAs were localized to steroidogenic cells in preantral, antral, and preovulatory follicles; corpora lutea; and interstitial glandular tissue. With newly developed antisera, we substantiated the expression of Per1 and Per2 in these cells by single/double immunohistochemistry. Furthermore, we visualized the temporal intracellular movements of PER1 and PER2 proteins. These findings suggest the existence of an ovarian circadian clock, which may play a role both locally and in the hypothalamo-pituitary-ovarian axis.

  19. Studio di prototipo di calorimetro per neutroni per l'esperimento ALICE

    CERN Document Server

    Arnaldi, R; Cicalò, C; Cortese, P; De Falco, A; Dellacasa, G; De Marco, N; Gallio, M; Macciotta, P; Masoni, A; Musso, A; Oppedisano, C; Piccotti, A; Puddu, G; Scomparin, E; Siddi, S; Serci, E; Soave, C; Usai, G L; Vercellin, Ermanno

    1999-01-01

    ALICE e uno dei quattro esperimenti previsti ad LHC, al CERN, il cui scopo e lo studio delle osservabili che danno informazioni rilevanti sulla formazione del quark gluon plasma, che potrebbe essere prodotto in collisioni centrali Pb-Pb, di energia nel centro di massa di 5.5 A TeV.Il parametro di impatto di tali collisioni verra determinato grazie ad un insieme di calorimetri per protoni e neutroni che misureranno l'energia portata in avanti dai nucleoni non interagenti(spettatori).E' stato costruito un prototipo di calometro per neutroni, formato da piani di fibre di quarzo, posti a 45 gradi rispetto all'asse del fascio e inframmezzati da piani di materiale passivo denso(tungsteno). La luce Cerenkov prodotta nelle fibre dallo sciame sviluppato nel materiale passivo,viene raccolta da guide ottiche in aria.Verranno presentati i rilustati di un test previsto al CERN SPS per il luglio 1999.

  20. Test Area B-70 Final Range Environmental Assessment, Revision 1

    Science.gov (United States)

    2009-06-01

    environmental impacts to Eglin ecosystems. Some of the main invasive non-native species of concern are Chinese tallow, cogon grass , Japanese climbing fern...2003a). Typical plant species include St. John’s Wort (Hypericum brachyphyllum) around the margins with spikerush (Eleocharis spp.), yellow-eyed grass ...Karst Pond Yellow-eyed Grass Xyris longisepala SE -- Pineland Hoary Pea Tephrosia mohrii ST -- Pineland Wild Indigo Baptista calycosa var villosa ST

  1. Ambienti narrativi per l'apprendimento

    Directory of Open Access Journals (Sweden)

    Giuliana Dettori

    2006-01-01

    Full Text Available Analisi degli ambienti di apprendimento narrativi e la loro potenzialità per l’apprendimento. Le storie possono essere uno strumento a sostegno dell’apprendimento che risulta naturale per tutti, e specialmente per bambini e ragazzi. Lo sviluppo delle TIC (Tecnologie dell’Informazione e della Comunicazione ed il loro crescente utilizzo in ambito didattico hanno fornito un’ampia gamma di strumenti per potenziare l’utilizzo educativo della narrativa, dando origine ad una consistente varieta’ di ambienti di apprendimento narrativi con obiettivi formativi differenti ed applicabili a diversi ambiti di studio.

  2. Evaluation of corneal anaesthesia after the application of topical 2 per cent lidocaine, 0.5 per cent bupivacaine and 1 per cent ropivacaine in dogs.

    Science.gov (United States)

    Costa, D; Peña, M T; Ríos, J; Leiva, M

    2014-05-10

    The objective of this study was to describe and compare the efficacy and duration of topical anaesthesia induced by 2 per cent lidocaine (L), 0.5 per cent bupivacaine (B) and 1 per cent ropivacaine (R) in the dog using 24 clinically healthy beagles with normal ocular examination. Dogs were randomly divided into three groups: 2 per cent lidocaine (n=8), 0.5 per cent bupivacaine (n=8) and 1 per cent ropivacaine (n=8). The baseline corneal touch threshold (CTT) was measured using a Cochet-Bonnet aesthesiometer. Following baseline CTT measurement, a single drop of the assigned anaesthetic was applied to each eye and the CTT was measured bilaterally within one minute after administration and every five minutes until the basal CTT value was restored. Data were analysed with non-parametric analysis of variance models and Dunnet's test for post hoc analysis. One per cent ropivacaine was the most effective drug (LCTTmax=3 cm, BCTTmax=2 cm, RCTTmax=0 cm; Pper cent ropivacaine had the maximal and quickest anaesthetic effect. This drug could be used for specific diagnostic procedures where quick and short, but effective, corneal anaesthesia is needed.

  3. Soil carbon 4 per mille

    NARCIS (Netherlands)

    Mulder, V.L.

    2017-01-01

    The ‘4 per mille Soils for Food Security and Climate’ was launched at the COP21 with an aspiration to increase global soil organic matter stocks by 4 per 1000 (or 0.4 %) per year as a compensation for the global emissions of greenhouse gases by anthropogenic sources. This paper surveyed the soil

  4. Plantas de cobertura de solo como hospedeiras alternativas de Colletotrichum guaranicola Cover crops as intermediate hosts to Colletotrichum guaranicola

    Directory of Open Access Journals (Sweden)

    L.J. Mileo

    2006-12-01

    Full Text Available As plantas de cobertura de solo usadas para suprimir o crescimento de plantas daninhas podem hospedar fungos fitopatogênicos. Para testar essa hipótese, elaborou-se este trabalho com o objetivo de avaliar o comportamento de nove espécies de plantas como possíveis hospedeiras do fungo Colletotrichum guaranicola. O experimento foi conduzido em casa de vegetação sob delineamento inteiramente casualizado, com quatro repetições. Cada vaso com três plantas da mesma espécie representou uma unidade experimental. As espécies que constituíram os tratamentos foram: Arachis pintoi, Calopogonium mucunoides, Chamaecrista rotundifolia, Crotalaria striata, Desmodium ovalifolium, Flemingia congesta, Mucuna aterrima, Pueraria phaseoloides e Tephrosia candida. Quarenta dias após a semeadura, as plantas foram inoculadas com suspensão de esporos de C. guaranicola na concentração de 10(5 conídios mL¹, enquanto as plantas testemunhas receberam somente água. As plantas foram mantidas em câmara úmida por 48 horas. Diariamente, foram feitas observações por 15 dias após a inoculação, para visualizar sintomas da doença. As espécies que não apresentaram sintomas de C. guaranicola foram Arachis pintoi, Chamaecrista rotundifolia, Desmodium ovalifolium, Flemingia congesta e Tephrosia candida, e as que manifestaram sintomas após a inoculação foram Calopogonium mucunoides, Crotalaria striata, Mucuna aterrima e Pueraria phaseoloides, que podem ser fontes de inóculo do patógeno da antracnose para o guaranazeiro.Cover crops used to suppress weed growth can be intermediate hosts to phytopathogenic fungi. To test this hypothesis, nine species of cover crops were evaluated as hosts to Colletotrichum guaranicola. The experiment was arranged in a randomized design, with four replicates, and conducted under greenhouse conditions. Each vase with three plants of one species constituted one plot. The species treated were: Arachis pintoi, Calopogonium

  5. PER-8, a Novel Extended-Spectrum β-Lactamase PER Variant, from an Acinetobacter baumannii Clinical Isolate in Nepal.

    Science.gov (United States)

    Tada, Tatsuya; Shrestha, Shovita; Shimada, Kayo; Ohara, Hiroshi; Sherchand, Jeevan B; Pokhrel, Bharat M; Kirikae, Teruo

    2017-03-01

    A novel PER-type extended-spectrum β-lactamase, PER-8, was identified in an Acinetobacter baumannii clinical isolate obtained in Nepal. The amino acid sequence of PER-8 has a substitution at position 39 (Gly to Glu) compared with that of PER-7. The k cat / K m ratio of PER-8 for aztreonam was lower than that of PER-7, while the k cat / K m ratio of PER-8 for imipenem was higher than that of PER-7. The genomic environment surrounding bla PER-8 was intI1 bla PSE-1 qacEDI sulI IS CR1-bla PER-8 gts sulI orfX on a 100-kb plasmid. Copyright © 2017 American Society for Microbiology.

  6. Soil Carbon 4 per mille

    Science.gov (United States)

    Minasny, Budiman; van Wesemael, Bas

    2017-04-01

    The '4 per mille Soils for Food Security and Climate' was launched at the COP21 aiming to increase global soil organic matter stocks by 4 per mille (or 0.4 %) per year as a compensation for the global emissions of greenhouse gases by anthropogenic sources. This paper surveyed the soil organic carbon (SOC) stock estimates and sequestration potentials from 20 regions in the world (New Zealand, Chile, South Africa, Australia, Tanzania, Indonesia, Kenya, Nigeria, India, China Taiwan, South Korea, China Mainland, United States of America, France, Canada, Belgium, England & Wales, Ireland, Scotland, and Russia) and asked whether the 4 per mille initiative is feasible. This study highlights region specific efforts and scopes for soil carbon sequestration. Reported soil C sequestration rates generally show that under best management practices, 4 per mille or even higher sequestration rates can be accomplished. High C sequestration rates (up to 10 per mille) can be achieved for soils with low initial SOC stock (topsoil less than 30 t C ha-1), and at the first twenty years after implementation of best management practices. In addition, areas that have reached equilibrium but not at their saturation level will not be able to further increase their sequestration. We found that most studies on SOC sequestration globally only consider topsoil (up to 0.3 m depth), as it is considered to be most affected by management techniques. The 4 per mille initiative was based on a blanket calculation of the whole global soil profile C stock, however the potential to increase SOC is mostly on managed agricultural lands. If we consider 4 per mille on global topsoil of agricultural land, SOC sequestration is about 3.6 Gt C per year, which effectively offset 40% of global anthropogenic greenhouse gas emissions. As a strategy for climate change mitigation, soil carbon sequestration buys time over the next ten to twenty years while other effective sequestration and low carbon technologies become

  7. Cross-layer based adaptive wireless traffic control for per-flow and per-station fairness

    Directory of Open Access Journals (Sweden)

    Siwamogsatham Siwaruk

    2011-01-01

    Full Text Available Abstract In the IEEE 802.11 wireless LANs, the bandwidth is not fairly shared among stations due to the distributed coordination function (DCF mechanism in the IEEE 802.11 MAC protocol. It introduces the per-flow and per-station unfairness problems between uplink and downlink flows, as the uplink flows usually dominate the downlink flows. In addition, some users may use greedy applications such as video streaming, which may prevent other applications from connecting to the Internet. In this article, we propose an adaptive cross-layer bandwidth allocation mechanism to provide per-station and per-flow fairness. To verify the effectiveness and scalability, our scheme is implemented on a wireless access router and numerous experiments in a typical wireless environment with both TCP and UDP traffic are conducted to evaluate performance of the proposed scheme.

  8. Medicare Hospital Spending Per Patient - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — The "Medicare hospital spending per patient (Medicare Spending per Beneficiary)" measure shows whether Medicare spends more, less or about the same per Medicare...

  9. Medicare Hospital Spending Per Patient - Hospital

    Data.gov (United States)

    U.S. Department of Health & Human Services — The "Medicare hospital spending per patient (Medicare Spending per Beneficiary)" measure shows whether Medicare spends more, less or about the same per Medicare...

  10. Medicare Hospital Spending Per Patient - State

    Data.gov (United States)

    U.S. Department of Health & Human Services — The "Medicare hospital spending per patient (Medicare Spending per Beneficiary)" measure shows whether Medicare spends more, less or about the same per Medicare...

  11. Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle.

    Science.gov (United States)

    Silva, Heloisa Cristina; Prette, Nancy; Lopes, Welber Daniel Zanetti; Sakamoto, Cláudio Alessandro M; Buzzulini, Carolina; Dos Santos, Thais Rabelo; Cruz, Breno Cayeiro; Teixeira, Weslen F Pires; Felippelli, Gustavo; Carvalho, Rafael Silveira; Maciel, Willian Giquelin; Soares, Vando Edésio; da Costa, Alvimar José

    2015-01-01

    The present work aimed to evaluate, through ten different studies, the therapeutic efficacy of a new pour-on formulation, containing 1.5 per cent ivermectin +0.5 per cent abamectin, against parasites of cattle. Results obtained on trials against Rhipicephalus (Boophilus) microplus showed that the pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained superior efficacy indexes against this ectoparasite, when compared with formulations containing 0.5 per cent ivermectin, 1 per cent ivermectin and the combination of 1 per cent abamectin +20 per cent levamisole. The results of efficacy of the ivermectin+abamectin and the 0.5 per cent ivermectin against Haematobia irritans were similar. Against Cochliomyia hominivorax larvae, all pour-on formulations tested (1.5 per cent ivermectin +0.5 per cent abamectin, 0.5 per cent ivermectin and 0.5 per cent abamectin), as well as 1 per cent doramectin administered subcutaneously, were considered ineffective. Cattle medicated with 1.5 per cent ivermectin +0.5 per cent abamectin, pour-on, remained free from parasitism by Dermatobia hominis larvae during 42 days (96 per cent efficacy), while values superior to 90 per cent were obtained by 0.5 per cent ivermectin (92 per cent) and 0.5 per cent abamectin (93 per cent) until the 42nd and 35th days post treatment, respectively. Against Haemonchus placei and Oesophagostomum radiatum, the pour-on of ivermectin+abamectin showed better efficacy than the 0.5 per cent ivermectin and 0.5 per cent abamectin. As to Cooperia punctata, there was no difference regarding efficacy results obtained by the avermectins combination and abamectin. The pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained high efficacy against R. (B.) microplus, D. hominis and some species of cattle gastrointestinal helminths when compared with formulations of 0.5 per cent ivermectin and 0.5 per cent abamectin administered through the same route.

  12. Pricing of on-line advertising: pay-per-view or pay-per-click?

    OpenAIRE

    Fjell, Kenneth

    2007-01-01

    We analyse the choice of pay-per-view (PPV) and price-per-click (PPC) when a web publisher is a price taker in the market for advertising banners, and the number of visits is decreasing in advertising. The main result is that the web publisher should always choose either PPV or PPC. If the click-through rate is exogenous, then the optimal amount of advertising is the same for both pricing metholds and the choice of pricing method is given by the click-through rate. If the click-through rate i...

  13. Bacillus licheniformis Contains Two More PerR-Like Proteins in Addition to PerR, Fur, and Zur Orthologues.

    Directory of Open Access Journals (Sweden)

    Jung-Hoon Kim

    Full Text Available The ferric uptake regulator (Fur family proteins include sensors of Fe (Fur, Zn (Zur, and peroxide (PerR. Among Fur family proteins, Fur and Zur are ubiquitous in most prokaryotic organisms, whereas PerR exists mainly in Gram positive bacteria as a functional homologue of OxyR. Gram positive bacteria such as Bacillus subtilis, Listeria monocytogenes and Staphylococcus aureus encode three Fur family proteins: Fur, Zur, and PerR. In this study, we identified five Fur family proteins from B. licheniformis: two novel PerR-like proteins (BL00690 and BL00950 in addition to Fur (BL05249, Zur (BL03703, and PerR (BL00075 homologues. Our data indicate that all of the five B. licheniformis Fur homologues contain a structural Zn2+ site composed of four cysteine residues like many other Fur family proteins. Furthermore, we provide evidence that the PerR-like proteins (BL00690 and BL00950 as well as PerRBL (BL00075, but not FurBL (BL05249 and ZurBL (BL03703, can sense H2O2 by histidine oxidation with different sensitivity. We also show that PerR2 (BL00690 has a PerR-like repressor activity for PerR-regulated genes in vivo. Taken together, our results suggest that B. licheniformis contains three PerR subfamily proteins which can sense H2O2 by histidine oxidation not by cysteine oxidation, in addition to Fur and Zur.

  14. Bacillus licheniformis Contains Two More PerR-Like Proteins in Addition to PerR, Fur, and Zur Orthologues

    Science.gov (United States)

    Ju, Shin-Yeong; Yang, Yoon-Mo; Ryu, Su-Hyun; Kwon, Yumi; Won, Young-Bin; Lee, Yeh-Eun; Youn, Hwan; Lee, Jin-Won

    2016-01-01

    The ferric uptake regulator (Fur) family proteins include sensors of Fe (Fur), Zn (Zur), and peroxide (PerR). Among Fur family proteins, Fur and Zur are ubiquitous in most prokaryotic organisms, whereas PerR exists mainly in Gram positive bacteria as a functional homologue of OxyR. Gram positive bacteria such as Bacillus subtilis, Listeria monocytogenes and Staphylococcus aureus encode three Fur family proteins: Fur, Zur, and PerR. In this study, we identified five Fur family proteins from B. licheniformis: two novel PerR-like proteins (BL00690 and BL00950) in addition to Fur (BL05249), Zur (BL03703), and PerR (BL00075) homologues. Our data indicate that all of the five B. licheniformis Fur homologues contain a structural Zn2+ site composed of four cysteine residues like many other Fur family proteins. Furthermore, we provide evidence that the PerR-like proteins (BL00690 and BL00950) as well as PerRBL (BL00075), but not FurBL (BL05249) and ZurBL (BL03703), can sense H2O2 by histidine oxidation with different sensitivity. We also show that PerR2 (BL00690) has a PerR-like repressor activity for PerR-regulated genes in vivo. Taken together, our results suggest that B. licheniformis contains three PerR subfamily proteins which can sense H2O2 by histidine oxidation not by cysteine oxidation, in addition to Fur and Zur. PMID:27176811

  15. Time-place learning and memory persist in mice lacking functional Per1 and Per2 clock genes.

    Science.gov (United States)

    Mulder, C; Van Der Zee, E A; Hut, R A; Gerkema, M P

    2013-12-01

    With time-place learning, animals link a stimulus with the location and the time of day. This ability may optimize resource localization and predator avoidance in daily changing environments. Time-place learning is a suitable task to study the interaction of the circadian system and memory. Previously, we showed that time-place learning in mice depends on the circadian system and Cry1 and/or Cry2 clock genes. We questioned whether time-place learning is Cry specific or also depends on other core molecular clock genes. Here, we show that Per1/Per2 double mutant mice, despite their arrhythmic phenotype, acquire time-place learning similar to wild-type mice. As well as an established role in circadian rhythms, Per genes have also been implicated in the formation and storage of memory. We found no deficiencies in short-term spatial working memory in Per mutant mice compared to wild-type mice. Moreover, both Per mutant and wild-type mice showed similar long-term memory for contextual features of a paradigm (a mild foot shock), measured in trained mice after a 2-month nontesting interval. In contrast, time-place associations were lost in both wild-type and mutant mice after these 2 months, suggesting a lack of maintained long-term memory storage for this type of information. Taken together, Cry-dependent time-place learning does not require Per genes, and Per mutant mice showed no PER-specific short-term or long-term memory deficiencies. These results limit the functional role of Per clock genes in the circadian regulation of time-place learning and memory.

  16. The Hepatitis C Genotype 1 Paradox: Cost per Treatment Is Increasing, but Cost per Cure Is Decreasing

    Directory of Open Access Journals (Sweden)

    Stephen D Shafran

    2015-01-01

    Full Text Available Significant attention has been focused on the perceived increase in the cost of antiviral treatment for hepatitis C genotype 1 infection since the approval of the first direct-acting antiviral agents in 2011. Using Canadian list prices, the present analysis points out a paradox: while the cost per antiviral regimen is increasing, the cost per cure is decreasing, especially with interferon-free therapy. In a publicly funded health care system, the lowest cost per cure is a more valuable measure of value for public money than the cost per regimen.

  17. The hepatitis C genotype 1 paradox: cost per treatment is increasing, but cost per cure is decreasing.

    Science.gov (United States)

    Shafran, Stephen D

    2015-01-01

    Significant attention has been focused on the perceived increase in the cost of antiviral treatment for hepatitis C genotype 1 infection since the approval of the first direct-acting antiviral agents in 2011. Using Canadian list prices, the present analysis points out a paradox: while the cost per antiviral regimen is increasing, the cost per cure is decreasing, especially with interferon-free therapy. In a publicly funded health care system, the lowest cost per cure is a more valuable measure of value for public money than the cost per regimen.

  18. Analysing malaria drug trials on a per-individual or per-clone basis: a comparison of methods.

    Science.gov (United States)

    Jaki, Thomas; Parry, Alice; Winter, Katherine; Hastings, Ian

    2013-07-30

    There are a variety of methods used to estimate the effectiveness of antimalarial drugs in clinical trials, invariably on a per-person basis. A person, however, may have more than one malaria infection present at the time of treatment. We evaluate currently used methods for analysing malaria trials on a per-individual basis and introduce a novel method to estimate the cure rate on a per-infection (clone) basis. We used simulated and real data to highlight the differences of the various methods. We give special attention to classifying outcomes as cured, recrudescent (infections that never fully cleared) or ambiguous on the basis of genetic markers at three loci. To estimate cure rates on a per-clone basis, we used the genetic information within an individual before treatment to determine the number of clones present. We used the genetic information obtained at the time of treatment failure to classify clones as recrudescence or new infections. On the per-individual level, we find that the most accurate methods of classification label an individual as newly infected if all alleles are different at the beginning and at the time of failure and as a recrudescence if all or some alleles were the same. The most appropriate analysis method is survival analysis or alternatively for complete data/per-protocol analysis a proportion estimate that treats new infections as successes. We show that the analysis of drug effectiveness on a per-clone basis estimates the cure rate accurately and allows more detailed evaluation of the performance of the treatment. Copyright © 2012 John Wiley & Sons, Ltd.

  19. 38 CFR 61.31 - Application for per diem.

    Science.gov (United States)

    2010-07-01

    ...) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.31 Application for per diem. (a) To apply for per diem, a capital grant recipient need only indicate the intent to receive per diem on the capital... per diem. (b) To apply for per diem, a non-capital grant recipient must obtain from VA a non-capital...

  20. Per Højholts monologer

    DEFF Research Database (Denmark)

    Nielsen, Klaus

    2010-01-01

    Per Højholt’s monologues: about Gitte, the paratext and the concept of the literary work in a book historic perspective To the field of literary studies book history and bibliography offer insights of immense value in particular with regards to the concept of the literary work. In this article I...... will present an example of how interpretation is affected when the literary work is viewed in a book historic and material perspective. The Danish postmodernist writer Per Højholt had his biggest commercial success with the work Gitte’s Monologues (1980-1984). The monologues enjoyed a wide listening audience...

  1. PER 2008(4)

    African Journals Online (AJOL)

    Tanya du Plessis

    Skills; Du Plessis 2007 PER http://www.puk.ac.za/ 15 Jan; Tjaden Legal research and writing; Teshima .... intermediaries or librarians when questions arise; .... standards of professional competence and ethical behavior. Throughout their ..... response to the question regarding the need for a common electronic location.

  2. 38 CFR 61.30 - Per diem-general.

    Science.gov (United States)

    2010-07-01

    ... HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.30 Per diem-general. VA provides per diem funds to capital grant recipients or to entities eligible to receive a capital grant, which established a program...

  3. Microblogging: quale valore per l’educazione? Presentazione per il pubblico italiano

    Directory of Open Access Journals (Sweden)

    Filippo Bruni

    2013-03-01

    Full Text Available Questo numero di Form@re raccoglie, come indicato dall’editoriale di Carmen Holotescu e Gabriela Grosseck, sei interventi, tutti relativi al microblogging, in cui si documenta come a livello europeo esistano una serie di esperienze e di risorse da un lato consolidate, dall’altro in forte evoluzione. In relazione al contesto italiano, quale tipo di pratiche e di osservazioni è possibile presentare? E quali stimoli è possibile trarre per ulteriori sperimentazioni? Il prossimo numero di Form@re offrirà una versione in lingua italiana dei contributi qui proposti, ma vorrebbe essere anche l’occasione per un’ulteriore riflessione attenta alle esperienze e ai dibattiti legati al contesto italiano. In tal senso i contributi presenti in questo numero aprono e offrono delle prime risposte a tutta una serie di questioni. Provando, sia pure con una modalità fin troppo sintetica, a individuare i punti essenziali, possono essere segnalate tre domande.

  4. PER1 Phosphorylation Specifies Feeding Rhythm in Mice

    Directory of Open Access Journals (Sweden)

    Zhiwei Liu

    2014-06-01

    Full Text Available Organization of circadian behavior, physiology, and metabolism is important for human health. An S662G mutation in hPER2 has been linked to familial advanced sleep-phase syndrome (FASPS. Although the paralogous phosphorylation site S714 in PER1 is conserved in mice, its specific function in circadian organization remains unknown. Here, we find that the PER1S714G mutation accelerates the molecular feedback loop. Furthermore, hPER1S714G mice, but not hPER2S662G mice, exhibit peak time of food intake that is several hours before daily energy expenditure peaks. Both the advanced feeding behavior and the accelerated clock disrupt the phase of expression of several key metabolic regulators in the liver and adipose tissue. Consequently, hPER1S714G mice rapidly develop obesity on a high-fat diet. Our studies demonstrate that PER1 and PER2 are linked to different downstream pathways and that PER1 maintains coherence between the circadian clock and energy metabolism.

  5. AppWeb per a una Aplicació per Android, iOS i Windows Phone

    OpenAIRE

    López Cuadros, Francesc Marc

    2016-01-01

    El projecte consisteix en desenvolupar una aplicació web que s'adapti a qualsevol dispositiu actual i que funcioni en qualsevol sistema operatiu. També ha de ser capaç de exprimir al màxim les característiques i funcionalitats del dispositiu en el que s'executa, per fer una aplicació molt més potent i atractiva per a l'usuari. El projecte consta de dues parts: una plataforma web totalment funcional adaptable a qualsevol dispositiu i una aplicació que permeti l'accés a aquesta plataforma i que...

  6. The inability of Bacillus licheniformis perR mutant to grow is mainly due to the lack of PerR-mediated fur repression.

    Science.gov (United States)

    Kim, Jung-Hoon; Yang, Yoon-Mo; Ji, Chang-Jun; Ryu, Su-Hyun; Won, Young-Bin; Ju, Shin-Yeong; Kwon, Yumi; Lee, Yeh-Eun; Youn, Hwan; Lee, Jin-Won

    2017-06-01

    PerR, a member of Fur family protein, is a metal-dependent H 2 O 2 sensing transcription factor that regulates genes involved in peroxide stress response. Industrially important bacterium Bacillus licheniformis contains three PerR-like proteins (PerR BL , PerR2, and PerR3) compared to its close relative Bacillus subtilis. Interestingly, unlike other bacteria including B. subtilis, no authentic perR BL null mutant could be established for B. licheniformis. Thus, we constructed a conditional perR BL mutant using a xylose-inducible promoter, and investigated the genes under the control of PerR BL . PerR BL regulon genes include katA, mrgA, ahpC, pfeT, hemA, fur, and perR as observed for PerR BS . However, there is some variation in the expression levels of fur and hemA genes between B. subtilis and B. licheniformis in the derepressed state. Furthermore, katA, mrgA, and ahpC are strongly induced, whereas the others are only weakly or not induced by H 2 O 2 treatment. In contrast to the B. subtilis perR null mutant which frequently gives rise to large colony phenotype mainly due to the loss of katA, the suppressors of B. licheniformis perR mutant, which can form colonies on LB agar, were all catalase-positive. Instead, many of the suppressors showed increased levels of siderophore production, suggesting that the suppressor mutation is linked to the fur gene. Consistent with this, perR fur double mutant could grow on LB agar without Fe supplementation, whereas perR katA double mutant could only grow on LB agar with Fe supplementation. Taken together, our data suggest that in B. licheniformis, despite the similarity in PerR BL and PerR BS regulon genes, perR is an essential gene required for growth and that the inability of perR null mutant to grow is mainly due to elevated expression of Fur.

  7. Nuovi strumenti per la gestione del dato geografico e per la ricerca archeologica

    Directory of Open Access Journals (Sweden)

    Gabriele Nole

    2011-04-01

    Full Text Available La Provincia di Potenza ha promosso un Protocollo di Intesa con la Direzione Regionale per i Beni Culturali e Paesaggistici della Basilicata per una ricerca scientifica finalizzata alla creazione di una banca-dati informatizzata dei Beni Culturali della Provincia di Potenza.New tools for geographic data management and archaeological researchThe  Province  of  Potenza  has  launched  a Memorandum  of  Understanding  with  the Regional Directorate for Cultural Heritage and  Landscape  of  Basilicata  for  scientific research  aimed  at  creating  a  computer-ized database of the Cultural Heritage of the Province.

  8. Nuovi strumenti per la gestione del dato geografico e per la ricerca archeologica

    Directory of Open Access Journals (Sweden)

    Gabriele Nole

    2011-04-01

    Full Text Available La Provincia di Potenza ha promosso un Protocollo di Intesa con la Direzione Regionale per i Beni Culturali e Paesaggistici della Basilicata per una ricerca scientifica finalizzata alla creazione di una banca-dati informatizzata dei Beni Culturali della Provincia di Potenza. New tools for geographic data management and archaeological research The  Province  of  Potenza  has  launched  a Memorandum  of  Understanding  with  the Regional Directorate for Cultural Heritage and  Landscape  of  Basilicata  for  scientific research  aimed  at  creating  a  computer-ized database of the Cultural Heritage of the Province.

  9. ENEA presenta sistema ADS per trattamento scorie

    CERN Multimedia

    2002-01-01

    "Arriva il sistema Ads (Accelerator driven system) per il trattamento dei rifiuti radioattivi. Lo studio di fattibilita' per l' innovativa tecnologia, realizzato da un gruppo di lavoro congiunto Enea, Cea, Cern e Ansaldo, e' stato presentato oggi nel corso di un workshop presieduto dal premio Nobel per la fisica, Carlo Rubbia" (1/2 page).

  10. Evaluation of image quality on a per-patient, per-vessel, and per-segment basis by noninvasive coronary angiography with 64-section computed tomography. Dual-source versus single-source computed tomography

    International Nuclear Information System (INIS)

    Nakashima, Yoshiteru; Okada, Munemasa; Washida, Yasuo; Miura, Toshiro; Fujimura, Tatsuo; Nao, Tomoko; Matsunaga, Naofumi

    2011-01-01

    The purpose of this study was to evaluate the image quality (IQ) of dual-source CT (DSCT) versus single-source CT (SSCT). A total of 100 patients underwent 64-section CT coronary angiography (50 DSCT, 50 SSCT). Three observers evaluated the IQ of each coronary segment using a four-point scale (1, excellent; 2, good; 3, fair; 4, no assessment). The IQ of DSCT coronary angiography was compared with SSCT coronary angiography on a per-patient, per-vessel, and per-segment basis using the chi-squared test. The DSCT image quality score (IQS) was significantly lower on a per-patient basis and per-vessel basis for all vessels and on a per-segment basis for some segments (1, 2, 4PD, 4AV, 7, 9, 11, 12, 13) compared with SSCT. The DSCT IQS was significantly lower for certain segments (2, 4PD, 11, 13) with high heart rates (≥70 beats/min). The DSCT IQS was significantly lower for certain segments (1, 2, 3, 4PD, 4AV, 7, 8, 9, 10, 12, 13) with low heart rates (<70 beats/min). DSCT showed a significantly better IQ than SSCT, especially in patients with low heart rates. (author)

  11. Intervals between multiple fractions per day

    International Nuclear Information System (INIS)

    Fowler, J.F.

    1988-01-01

    Assuming the linear quadratic model for dose-response curves enables the proportion of repairable damage to be calculated for any size of dose per fraction. It is given by the beta (dose squared) term, and represents a larger proportion of the total damage for larger doses per fraction, but also for late-reacting than for early-reacting tissues. For example at 2 Gy per fraction, repairable damage could represent nearly half the total damage in late-reacting tissues but only one fifth in early-reacting tissues. Even if repair occurs at the same rate in both tissues, it will obviously take longer for 50% of the damage to fade to an undetectable level (3 or 5%) than for 20% to do so. This means that late reactions require longer intervals than early reactions when multiple fraction per day radiotherapy is planned, even if the half-lives of repair are not different. (orig.)

  12. “The Age of Capital”: Pers, Uang, dan Kekuasaan

    Directory of Open Access Journals (Sweden)

    Ignatius Haryanto

    2003-06-01

    Full Text Available Pers, uang, dan kekuasaan merupakan tiga unsur yang membuat roda industri pers berputar dengan lancar. Tiga unsur tersebut menjadi titik tolak untuk mengupas permasalahan aktual yang dihadapi pers pasca pemerintahan Soeharto, setelah negara tidak lagi menjadi penguasa pers. Simpulan yang disampaikan menunjukkan indikasi terwujudnya The Age of Capital dalam Industri Pers Indonesia, yaitu tatkala modal menjadi kekuatan utama yang menguasai urat nadi kehidupan pers, dan pada akhirnya menghilangkan mekanisme pers yang sehat dan objektif. Sejumlah contoh yang terjadi menunjukkan betapa Dewan Pers sendiri, yang diharapkan mampu menjamin keberlangsungan kehidupan pers yang sehat, ternyata telah terkooptasi oleh kapitalisasi modal para pengusaha yang berkepentingan dengan pembentukan citra produk mereka.

  13. Per maand of per kWh?: beoordeling van de effecten van een ander tariefsysteem voor kleinverbruikers electriciteit

    NARCIS (Netherlands)

    Aalbers, R.F.A.; de Nooij, M.

    2006-01-01

    Dit rapport bepaalt de effecten van de invoering van een capaciteitstarief voor de kosten van het transport van elektriciteit voor kleinverbruikers. Centraal kenmerk van een capaciteitstarief is dat kleinverbruikers niet langer per afgenomen kWh, maar een vast bedrag per aansluiting betalen. In het

  14. Per Pettersons Ekkoland – Danmark

    DEFF Research Database (Denmark)

    Gemzøe, Anker

    2011-01-01

    Artiklen introducerer til Per Pettersons forfatterskab med udgangspunkt i en analyse af hans første roman Ekkoland – med hovedvægt på handlingssted, genre og stil. Titlen gengiver Paul la Cours betegnelse for Jylland, og romanen foregår i Nordjylland. Ekkoland er mere novelleagtig end nogen af de...... senere romaner, men afprøver samtidig nogle af Per Petterson væsentlige romangreb siden hen, fx udgangspunktet i hovedpersonens bevidsthed og de smidige skift mellem tider og steder – som her altså også er lande og sprog....

  15. Rampa hidràulica per a bolcatge

    OpenAIRE

    Priego Minguell, Isaac

    2004-01-01

    El projecte es basa en el desenvolupament d’una rampa hidràulica per a l’avaluació dels riscos de bolcatge (RHB), que inclou una part mecànica i una part hidràulica. L’objectiu de dissenyar aquesta rampa hidràulica ha estat amb l’únic propòsit de fer una avaluació de la seguretat per bolcatge per a vehicles industrials (tractors de grans dimensions).

  16. Cost per remission and cost per response with infliximab, adalimumab, and golimumab for the treatment of moderately-to-severely active ulcerative colitis.

    Science.gov (United States)

    Toor, Kabirraaj; Druyts, Eric; Jansen, Jeroen P; Thorlund, Kristian

    2015-06-01

    To determine the short-term costs per sustained remission and sustained response of three tumor necrosis factor inhibitors (infliximab, adalimumab, and golimumab) in comparison to conventional therapy for the treatment of moderately-to-severely active ulcerative colitis. A probabilistic Markov model was developed. This included an 8-week induction period, and 22 subsequent 2-week cycles (up to 1 year). The model included three disease states: remission, response, and relapse. Costs were from a Canadian public payer perspective. Estimates for the additional cost per 1 year of sustained remission and sustained response were obtained. Golimumab 100 mg provided the lowest cost per additional remission ($935) and cost per additional response ($701) compared with conventional therapy. Golimumab 50 mg yielded slightly higher costs than golimumab 100 mg. Infliximab was associated with the largest additional number of estimated remissions and responses, but also higher cost at $1975 per remission and $1311 per response. Adalimumab was associated with the largest cost per remission ($7430) and cost per response ($2361). The cost per additional remission and cost per additional response associated with infliximab vs golimumab 100 mg was $14,659 and $4753, respectively. The results suggest that the additional cost of 1 full year of remission and response are lowest with golimumab 100 mg, followed by golimumab 50 mg. Although infliximab has the highest efficacy, it did not exhibit the lowest cost per additional remission or response. Adalimumab produced the highest cost per additional remission and response.

  17. Women in Physics in Perú

    Science.gov (United States)

    Loayza, María Luisa Cerón; Vásquez, Yezeña Huaypar; Cabrejos, Jorge Aurelio Bravo

    2009-04-01

    The numbers of women receiving undergraduate and master's degrees in physics from San Marcos National University and undergraduate physics degrees from San Luis Gonzaga National University in Perú are reported. The number of undergraduate degrees in physics has increased for women in San Marcos University, but not for women earning master's degrees. Why don't women complete their post-degree studies? Economics and gender stereotypes are factors that women in Perú have to fight each day. Perú does not have a good scholar program in science, so few students are interested in beginning their university careers in science. Improvements in science education are needed for our country to reach its potential.

  18. The difference in in vivo sensitivity between Bacillus licheniformis PerR and Bacillus subtilis PerR is due to the different cellular environments.

    Science.gov (United States)

    Kim, Jung-Hoon; Won, Young-Bin; Ji, Chang-Jun; Yang, Yoon-Mo; Ryu, Su-Hyun; Ju, Shin-Yeong; Kwon, Yumi; Lee, Yeh-Eun; Lee, Jin-Won

    2017-02-26

    PerR, a member of Fur family of metal-dependent regulators, is a major peroxide sensor in many Gram positive bacteria, and controls the expression of genes involved in peroxide resistance. Bacillus licheniformis, a close relative to the well-studied model organism Bacillus subtilis, contains three PerR-like proteins (PerR BL , PerR2 and PerR3) in addition to Fur and Zur. In the present study, we characterized the role of PerR BL in B. licheniformis. In vitro and in vivo studies indicate that PerR BL , like PerR BS , uses either Fe 2+ or Mn 2+ as a corepressor and only the Fe 2+ -bound form of PerR BL senses low levels of H 2 O 2 by iron-mediated histidine oxidation. Interestingly, regardless of the difference in H 2 O 2 sensitivity, if any, between PerR BL and PerR BS , B. licheniformis expressing PerR BL or PerR BS could sense lower levels of H 2 O 2 and was more sensitive to H 2 O 2 than B. subtilis expressing PerR BL or PerR BS . This result suggests that the differences in cellular milieu between B. subtilis and B. licheniformis, rather than the intrinsic differences in PerR BS and PerR BL per se, affect the H 2 O 2 sensing ability of PerR inside the cell and the H 2 O 2 resistance of cell. In contrast, B. licheniformis and B. subtilis expressing Staphylococcus aureus PerR (PerR SA ), which is more sensitive to H 2 O 2 than PerR BL and PerR BS , were more resistant to H 2 O 2 than those expressing either PerR BL or PerR BS . This result indicates that the sufficient difference in H 2 O 2 susceptibility of PerR proteins can override the difference in cellular environment and affect the resistance of cell to H 2 O 2 . Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Biotechnological Applications of Microbial (Per)chlorate Reduction.

    Science.gov (United States)

    Wang, Ouwei; Coates, John D

    2017-11-24

    While the microbial degradation of a chloroxyanion-based herbicide was first observed nearly ninety years ago, only recently have researchers elucidated the underlying mechanisms of perchlorate and chlorate [collectively, (per)chlorate] respiration. Although the obvious application of these metabolisms lies in the bioremediation and attenuation of (per)chlorate in contaminated environments, a diversity of alternative and innovative biotechnological applications has been proposed based on the unique metabolic abilities of dissimilatory (per)chlorate-reducing bacteria (DPRB). This is fueled in part by the unique ability of these organisms to generate molecular oxygen as a transient intermediate of the central pathway of (per)chlorate respiration. This ability, along with other novel aspects of the metabolism, have resulted in a wide and disparate range of potential biotechnological applications being proposed, including enzymatic perchlorate detection; gas gangrene therapy; enhanced xenobiotic bioremediation; oil reservoir bio-souring control; chemostat hygiene control; aeration enhancement in industrial bioreactors; and, biogenic oxygen production for planetary exploration. While previous reviews focus on the fundamental science of microbial (per)chlorate reduction (for example see Youngblut et al., 2016), here, we provide an overview of the emerging biotechnological applications of (per)chlorate respiration and the underlying organisms and enzymes to environmental and biotechnological industries.

  20. What does it mean to be average? : the miles per gallon versus gallons per mile paradox revisited

    NARCIS (Netherlands)

    Haans, A.

    2008-01-01

    In the efficiency paradox, which was introduced by Hand (1994; J R Stat Soc A, 157, 317-356), two groups of engineers are in disagreement about the average fuel efficiency of a set of cars. One group measured efficiency on a miles per gallon scale, the other on a gallons per mile scale. In the

  1. Per-oral cholangioscopy

    OpenAIRE

    Monga, Amitabh; Ramchandani, Mohan; Reddy, D Nageshwar

    2011-01-01

    Direct endoscopic views of bile duct have been described in literature since the 1970s. Since then rapid strides have been made with the advent of technologically advanced systems with better image quality and maneuverability. The single operator semi-disposable per-oral cholangioscope and other novel methods such as the cholangioscopy access balloon are likely to revolutionize this field. Even though cholangioscopy is currently used primarily for characterization of indeterminate strictures ...

  2. Collaboration on HiPER EU FP7 Project

    International Nuclear Information System (INIS)

    Rhee, Yong Joo; Han, Jae Min; Nam, Sung Mo; Chung, Chin Man; Lim, Chang Hwan; Cha, Yong Ho; Kwon, Duck Hee

    2011-06-01

    European Union started the HiPER project to establish a laser fusion research facility for energy production in Europe. Feasibility study and conceptual design has been performed for 2 years from 2005 and based on this study HiPER preparatory phase project has been proposed in 2007 as a EU FP7 project by 10 European countries and approved by EC. The project started in April of 2008 officially for 36 months until April of 2011. HiPER is a unique pure civilian laser fusion research facility and supported by ESFRI road map. KAERI has been participating HiPER from the feasibility study phase and still collaborating with HiPER EU FP7 project officially with the funding from the Korean government. Through this technical collaboration, participation in the joint experiments at large laser facilities has been possible and infrastructure of scientists exchange has been established Although the EU FP7 HiPER preparatory phase project ends at April of 2011 (actually it is extended until 2013 without further budget allocation fm EC) the total HiPER programme is planned to continue for more than 10 more years until the construction and commission of the fusion reactor. And KAERI also continue to participate in the HiPER programme in the future until the end of the programme

  3. The Nitrate/(Per)Chlorate Relationship on Mars

    Science.gov (United States)

    Stern, Jennifer C.; Sutter, Brad; Jackson, W. Andrew; Navarro-Gonzalez, Rafael; McKay, Christopher P.; Ming, Douglas W.; Archer, P. Douglas; Mahaffy, Paul R.

    2017-01-01

    Nitrate was recently detected in Gale Crater sediments on Mars at abundances up to approximately 600 mg/kg, confirming predictions of its presence at abundances consistent with models based on impact-generated nitrate and other sources of fixed nitrogen. Terrestrial Mars analogs, Mars meteorites, and other solar system materials help establish a context for interpreting in situ nitrate measurements on Mars, particularly in relation to other cooccuring salts. We compare the relative abundance of nitrates to oxychlorine (chlorate and/or perchlorate, hereafter (per)chlorate) salts on Mars and Earth. The nitrate/(per)chlorate ratio on Mars is greater than 1, significantly lower than on Earth (nitrate/(per)chlorate greater than 10(exp.3)), suggesting not only the absence of biological activity but also different (per)chlorate formation mechanisms on Mars than on Earth.

  4. 36 CFR 1150.48 - PER: Citation, answer, amendment.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false PER: Citation, answer...; Pleadings and Motions § 1150.48 PER: Citation, answer, amendment. (a) Unless otherwise specified, other..., the citation shall request PER when it appears to the Executive Director that immediate and...

  5. Il Raffrescamento per Ventilazione

    DEFF Research Database (Denmark)

    Perino, Marco; Heiselberg, Per Kvols

    2016-01-01

    termicamente e sempre più a tenuta d'aria. Tali misure hanno consentito indubbiamente di ridurre la domanda energetica per il riscaldamento invernale, ma hanno determinato delle crescenti problematiche di surriscaldamento dell'ambiente interno. Molti degli edifici ad alta efficienza energeti-ca di nuova...

  6. Relevansi Nilai Selisih Loans Book Value dan Loans Fair Value, Book Value Per Share, Earnings Per Share dan Ukuran Perusahaan

    Directory of Open Access Journals (Sweden)

    Dina Bakti Pertiwi

    2015-01-01

    Full Text Available One of the impacts of IFRS convergence is the tendency to leave historical cost to the fair value primarily for financial instruments, one of which is bank loans. Therefore, the benefit of the use of historical cost and fair value needs to be examined. This study aims to evaluate the relationship of the difference between loan book value and fair value, book value per share, earnings per share and the company size to the stock price of banks that use accounting standard that has been converged to IFRS. The samples used are banks listed in Indonesia Stock Exchange during the period of 2010-2013. The relationship between the difference loans book value and fair value, book value per share, earnings per share and the size with the stock price were analyzed using multiple linear regression. The results of this study indicate that the difference between loans book value and fair value, book value per share, earnings per share and the size can be used to predict the stock price of bank. Thus, the difference between loan book value and fair value of financial instruments have a relevant value.

  7. 77 FR 45719 - Proposed Information Collection (Per Diem for Nursing Home Care of Veterans in State Homes; Per...

    Science.gov (United States)

    2012-08-01

    ... per diem to State homes providing nursing home and adult day health services care to Veterans. VA... Diem for Nursing Home Care of Veterans in State Homes; Per Diem for Adult Day Care of Veterans in State... information needed to ensure that nursing home and adult day health care facilities are providing high quality...

  8. Bacterial PerO Permeases Transport Sulfate and Related Oxyanions.

    Science.gov (United States)

    Hoffmann, Marie-Christine; Pfänder, Yvonne; Tintel, Marc; Masepohl, Bernd

    2017-07-15

    Rhodobacter capsulatus synthesizes the high-affinity ABC transporters CysTWA and ModABC to specifically import the chemically related oxyanions sulfate and molybdate, respectively. In addition, R. capsulatus has the low-affinity permease PerO acting as a general oxyanion transporter, whose elimination increases tolerance to molybdate and tungstate. Although PerO-like permeases are widespread in bacteria, their function has not been examined in any other species to date. Here, we present evidence that PerO permeases from the alphaproteobacteria Agrobacterium tumefaciens , Dinoroseobacter shibae , Rhodobacter sphaeroides , and Sinorhizobium meliloti and the gammaproteobacterium Pseudomonas stutzeri functionally substitute for R. capsulatus PerO in sulfate uptake and sulfate-dependent growth, as shown by assimilation of radioactively labeled sulfate and heterologous complementation. Disruption of perO genes in A. tumefaciens , R. sphaeroides , and S. meliloti increased tolerance to tungstate and, in the case of R. sphaeroides , to molybdate, suggesting that heterometal oxyanions are common substrates of PerO permeases. This study supports the view that bacterial PerO permeases typically transport sulfate and related oxyanions and, hence, form a functionally conserved permease family. IMPORTANCE Despite the widespread distribution of PerO-like permeases in bacteria, our knowledge about PerO function until now was limited to one species, Rhodobacter capsulatus In this study, we showed that PerO proteins from diverse bacteria are functionally similar to the R. capsulatus prototype, suggesting that PerO permeases form a conserved family whose members transport sulfate and related oxyanions. Copyright © 2017 American Society for Microbiology.

  9. Planeamiento estratégico del Perú

    OpenAIRE

    Paisano Ccasa, Wilfredo; Paucar Lescano, Christian Paul; Thorne Rivera, Jackeline Elizabeth; Valverde Noel, Hugo Frank

    2017-01-01

    Perú SA en los últimos años tuvo un crecimiento económico gracias a la exportación de sus principales commodities, productos no tradicionales y una mayor presencia de la marca Perú. Por otro lado cuenta con una infraestructura aún insuficiente, una educación pública deficiente, bajo control contra la corrupción y una falta de prevención ante fenómenos naturales. Bajo esa premisa, el presente trabajo busca mostrar un Plan Estratégico de Perú SA de largo plazo que contenga políti...

  10. Alstroemeriaceae en Perú y áreas vecinas

    Directory of Open Access Journals (Sweden)

    Anton Hofreiter

    2006-10-01

    Full Text Available Las Alstroemeriaceae peruanas fueron revisadas por última vez por Killip (1936. Es necesaria una nueva revisión. Cinco viajes de campo de varias semanas cada uno fueron emprendidos a Sudamérica con el fin de estudiar las plantas in situ. En el presente trabajo se describe la historia taxonómica y colección de los géneros con especial énfasis en el Perú. El área descrita no considera fronteras políticas sino unidades geográficas de acuerdo a Baumann (1988, Berry (1982, Duellman (1979, Simpson (1975, 1979 y Weigend (2002. Se reconocen cinco unidades geográficas: Región Amotape-Huancabamba (Ecuador, Perú, Cordillera Occidental (Perú, Cordillera Central (Perú, Cordillera Oriental (Bolivia, Perú y el Altiplano (Bolivia, Perú. Se brinda una clave taxonómica en inglés y español para determinar las especies del Perú. Para cada una de las especies se discute la forma típica de crecimiento y su variabilidad, preferencias de hábitat y distribución general. Se identifican las especies de Ruiz & Pavón (1802. Ellos describieron en su Flora de Chile y Perú 23 especies de Alstroemeria, 18 fueron de Perú, ahora 17 son incluidas en Bomarea, todas proceden de Perú. El género Bomarea está subdividido en 4 subgéneros: Baccata, Bomarea s. str., Sphaerine y Winchurea (Hofreiter & Tillich, 2002. Alstroemeria no es dividido en subgéneros, pero existen dos grupos reconocidos, Alstroemeria de Chile y Brasil. En el área de estudio se encuentran dos especies de Alstroemeria y 68 de Bomarea, de ellas 43 especies pertenecen al subgénero Bomarea, 9 especies al subgénero Sphaerine y 16 especies al subgénero Wichuraea. El subgénero Baccata no se encuentra en el área de estudio. Seis de las especies del género Bomarea son nuevas para la ciencia: B. amazonica, B. libertadensis, B. lopezii, B. macusanii, B. pseudopurpurea, B. weigendii.

  11. Per3 VNTR polymorphism and chronic heart failure.

    Science.gov (United States)

    Lipkova, Jolana; Bienertova-Vasku, Julie Anna; Spinarova, Lenka; Bienert, Petr; Hlavna, Marian; Pavkova Goldbergova, Monika; Parenica, Jiri; Spinar, Jindrich; Vasku, Anna

    2014-01-01

    The aim of this study was to investigate the relationship between gene Period3 (Per3) variable number tandem repeat (VNTR) polymorphism and chronic heart failure (CHF). The study subjects (372 patients of Caucasian origin with CHF and 332 healthy controls) were genotyped for Per3 VNTR polymorphism using an allele-specific PCR. No significant differences in genotype or Per3 VNTR allele frequencies were found between CHF cases and controls (Pg=0.30, Pa=0.52). No significant differences were uncovered either between CHF cases according to etiology (DCMP vs. IHD; Pg=0.87, Pa=0.91). In the multivariate regression modeling, no predictive function of VNTR Per3 polymorphism on ejection fraction or NYHA class, hyperlipidaemia or type II diabetes risk was found. Per3 VNTR polymorphism is not a major risk factor for chronic heart failure or a factor modulating the severity of the CHF in this population.

  12. (Per)chlorate in Biology on Earth and Beyond.

    Science.gov (United States)

    Youngblut, Matthew D; Wang, Ouwei; Barnum, Tyler P; Coates, John D

    2016-09-08

    Respiration of perchlorate and chlorate [collectively, (per)chlorate] was only recognized in the last 20 years, yet substantial advances have been made in our understanding of the underlying metabolisms. Although it was once considered solely anthropogenic, pervasive natural sources, both terrestrial and extraterrestrial, indicate an ancient (per)chlorate presence across our solar system. These discoveries stimulated interest in (per)chlorate microbiology, and the application of advanced approaches highlights exciting new facets. Forward and reverse genetics revealed new information regarding underlying molecular biology and associated regulatory mechanisms. Structural and functional analysis characterized core enzymes and identified novel reaction sequences. Comparative genomics elucidated evolutionary aspects, and stress analysis identified novel response mechanisms to reactive chlorine species. Finally, systems biology identified unique metabolic versatility and novel mechanisms of (per)chlorate respiration, including symbiosis and a hybrid enzymatic-abiotic metabolism. While many published studies focus on (per)chlorate and their basic metabolism, this review highlights seminal advances made over the last decade and identifies new directions and potential novel applications.

  13. Emilio Pasquini, ed., Studi e problemi di critica testuale: 1960-2010. Per i 150 anni della Commissione per i testi di lingua

    OpenAIRE

    Di Stefano, Giuseppe

    2016-01-01

    Reseña de Emilio Pasquini, ed., Studi e problemi di critica testuale: 1960-2010. Per i 150 anni della Commissione per i testi di lingua, Commissione per i testi di lingua (Collezione di opere inedite o rare, 169), Bologna, 2012, x + 320 pp. ISBN: 9788898096152.

  14. Does immigration boost per capita income?

    DEFF Research Database (Denmark)

    Felbermayer, Gabriel; Hiller, Sanne; Sala, Davide

    2010-01-01

    Using a cross-section of countries, we adapt Frankel and Romer's (1999) IV strategy to international labor mobility. Controlling for institutional quality, trade, and financial openness, we establish a robust and non-negative causal effect of immigration on real per capita income.......Using a cross-section of countries, we adapt Frankel and Romer's (1999) IV strategy to international labor mobility. Controlling for institutional quality, trade, and financial openness, we establish a robust and non-negative causal effect of immigration on real per capita income....

  15. Does Immigration Boost Per Capita Income?

    DEFF Research Database (Denmark)

    Felbermayr, Gabriel J.; Hiller, Sanne; Sala, Davide

    Using a cross-section of countries, we adapt Frankel and Romer's (1999) IV strategy to international labor mobility. Controlling for institutional quality, trade, and ?nancial openness, we establish a robust and non-negative causal e?ect of immigration on real per-capita income.......Using a cross-section of countries, we adapt Frankel and Romer's (1999) IV strategy to international labor mobility. Controlling for institutional quality, trade, and ?nancial openness, we establish a robust and non-negative causal e?ect of immigration on real per-capita income....

  16. Per un'apologia della maschera

    Directory of Open Access Journals (Sweden)

    Alessio Bertò

    2015-08-01

    Full Text Available Il presente studio si propone, attraverso una breve esegesi delle teorie sulla maschera e il processo di mascheratura, rivalutare la funzione dell'atto e la figura del travestimento e la maschera, ridotta oggi – se non relegata in un uno strumento di lavoro tecnico – a mero strumento, astratto o concreto, di falsificazione o inganno progettato per nascondere la vera identità dell'utente. Il proposito di maschera della maschera come chiave di accesso a una realtà interiore del soggetto e come una liberazione del sé in stretti canali prefigurati dalla società sempre più impegnato nella formazione di modelli predefiniti di identità, può essere intesa analizzando il significato psicologico della maschera, insieme agli studi antropologici che hanno permesso la scoperta di segreti e le funzioni di questa nelle società antiche, così come nella contemporanea. Questo viaggio ci porterà alla la porta del Sé, in cui la maschera non nasconde un'altra identità, ma apre la strada alla produzione della Persona, permettere il soggetto di porsi al concorso di tutti i giorni della realtà, l’espressione dell'Essere-in-Mondo, per per consentire l'adattamento e la sopravvivenza, garantire la libertà di espressione senza perdersi nell'anonimato di una maschera di morte, "il conformismo e le mode (ideologicos, culturales, sociales, sono i guardiani segreti".

  17. Emilio Pasquini, ed., Studi e problemi di critica testuale: 1960-2010. Per i 150 anni della Commissione per i testi di lingua

    Directory of Open Access Journals (Sweden)

    Giuseppe Di Stefano

    2016-01-01

    Full Text Available Reseña de Emilio Pasquini, ed., Studi e problemi di critica testuale: 1960-2010. Per i 150 anni della Commissione per i testi di lingua, Commissione per i testi di lingua (Collezione di opere inedite o rare, 169, Bologna, 2012, x + 320 pp. ISBN: 9788898096152.

  18. HyPer Family Probes: State of the Art.

    Science.gov (United States)

    Bilan, Dmitry S; Belousov, Vsevolod V

    2016-05-01

    Hydrogen peroxide (H2O2) is not only a key mediator of oxidative stress but also one of the most important cellular second messengers. This small short-lived molecule is involved in the regulation of a wide range of different biological processes, including regulation of cellular signaling pathways. Studying the role of H2O2 in living systems would be challenging without modern approaches. A genetically encoded fluorescent biosensor, HyPer, is one of the most effective tools for this purpose. HyPer has been used by many investigators of redox signaling in various models of different scales: from cytoplasmic subcompartments and single cells to tissues of whole organisms. In many studies, the results obtained using HyPer have enabled a better understanding of the roles of H2O2 in these biological processes. However, much remains to be learned. In this review, we focus on the uses of HyPer. We provide a general description of HyPer and its improved versions. Separate chapters are devoted to the results obtained by various groups who have used this biosensor for their experiments in living cells and organisms. HyPer is an effective tool for H2O2 imaging in living systems as indicated by the increasing numbers of publications each year since its development. However, this biosensor requires further improvements. In particular, much brighter and more pH-stable versions of HyPer are necessary for imaging in mammalian tissues. Antioxid. Redox Signal. 24, 731-751.

  19. X ray spectra of X Per. [oso-8 observations

    Science.gov (United States)

    Becker, R. H.; Boldt, E. A.; Holt, S. S.; Pravdo, S. H.; Robinson-Saba, J.; Serlemitsos, P. J.; Swank, J. H.

    1978-01-01

    The cosmic X-ray spectroscopy experiment on OSO-8 observed X Per for twenty days during two observations in Feb. 1976 and Feb. 1977. The spectrum of X Per varies in phase with its 13.9 min period, hardening significantly at X-ray minimum. Unlike other X-ray binary pulsar spectra, X Per's spectra do not exhibit iron line emission or strong absorption features. The data show no evidence for a 22 hour periodicity in the X-ray intensity of X Per. These results indicate that the X-ray emission from X Per may be originating from a neutron star in a low density region far from the optically identified Be star.

  20. What Per Cent Cruise?

    Science.gov (United States)

    George M. Furnival

    1953-01-01

    Cruising timber is ordinarily a job of sampling, in which the quantity of timber on a tract is estimated from the quantity on a part of the tract. The difficulty is to determine what part (per cent) of the tract should be sampled to attain a given level of accuracy. This article gives a rule-ofthumb that can be applied with fair reliability to most Southern forests....

  1. Campagna di social marketing per sensibilizzare all'uso delle cinture di sicurezza e dispositivi per bambini

    Directory of Open Access Journals (Sweden)

    S. Cinquetti

    2003-05-01

    Full Text Available

    Obiettivi: aumento del 10% dell’uso delle cinture di sicurezza anteriori e posteriori e del 20% dei seggiolini per bambini nella Regione del Veneto.

    Metodi: il Programma Regionale di Prevenzione dei Traumi da Traffico è stato varato nel 1998 e rifinanziato nel 2002 per un secondo triennio. Fa capo alla Direzione per la Prevenzione dell’Assessorato alle Politiche Sanitarie del Veneto, coinvolge i Dipartimenti di Prevenzione di tutte le Aziende ULSS del Veneto e ha come capofila l’azienda ULSS 7 di Pieve di Soligo (TV. Nell’ambito del programma, il 16 maggio 2003 è stata avviata una campagna di marketing sociale finanziata dalla fondazione CARIVERONA e commissionata ad un’ agenzia pubblicitaria leader del settore. La campagna è stata preceduta da ricerca formativa con 19 focus group e 12 interviste, volta ad analizzare il punto di vista dei diversi target, nonché degli attori principali coinvolti (Forze dell’Ordine, autoscuole, etc. Dopo un test di gradimento, la campagna è partita con spot televisivi e radiofonici, inserzioni nei giornali e manifesti informativi destinati alle scuole medie superiori, alle scuole guida nonché agli ambulatori dei medici di famiglia. Attraverso i media si sostiene una serie di azioni nel territorio che coinvolgeranno le amministrazioni comunali, le forze di polizia e le associazioni di volontariato.

    Risultati: l’efficacia della campagna viene valutata attraverso due distinte rilevazioni dell’uso delle cinture di sicurezza/seggiolini, confrontando i dati raccolti prima della campagna e dopo.

    Conclusioni: i traumi da traffico rappresentano nel Veneto un’importante causa di mortalità e morbosità. Il programma regionale ha utilizzato la tecnica innovativa del marketing sociale come strumento essenziale per sostenere i cambiamenti comportamentali necessari a prevenire l’incidentalità da traffico nel

  2. The Impact of Corruption on GDP Per Capita

    Directory of Open Access Journals (Sweden)

    Nazar Mustapha

    2014-10-01

    Full Text Available The paper studies the impact of corruption on the GDP per capita. A panel data covers the period between 2003 and 2011. The objective is to test the hypothesis that there is a strong negative impact of corruption on the GDP per capita. Three tests were conducted, the pool OLS, The Fixed Effect and the Random effect estimations. The main result of this study is that all three tests had shown strong statistically significant negative impact of corruption on the GDP per capita.

  3. 33 CFR 5.57 - Traveling expenses and per diem.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Traveling expenses and per diem... GENERAL COAST GUARD AUXILIARY § 5.57 Traveling expenses and per diem. A member of the Auxiliary, when assigned to specific duties, may be paid actual necessary traveling expenses, including a per diem...

  4. [Measurement of antimicrobial consumption using DDD per 100 bed-days versus DDD per 100 discharges after the implementation of an antimicrobial stewardship program].

    Science.gov (United States)

    Collado, Roberto; Losa, Juan Emilio; Álvaro, Elena Alba; Toro, Piedad; Moreno, Leonor; Pérez, Montserrat

    2015-12-01

    Monitoring antimicrobial consumption in hospitals is a necessary measure. The indicators commonly employed do not clearly reflect the antibiotic selection pressure. The objective of this study is to evaluate two different methods that analyze antimicrobial consumption based on DDD, per stay and per discharge, before and after the implementation an antimicrobial stewardship program. Comparative pre-post study of antimicrobial consumption with the implementation of an antimicrobial stewardship program using DDD per 100 bed-days and DDD per 100 discharges as indicators. Hospital bed days remained stable and discharges increased slightly along the period of study Antibiotic consumption in DDD per 100 bed-days decreased by 2.5% versus 3.8% when expressed as DDD per 100 discharges. Antifungal consumption decreased by more than 50%. When average hospital stay decreases, reductions in the consumption of antimicrobials with an antimicrobial stewardship program system occur at the expense of reducing the number of patients receiving treatment, while increases occur due to longer durations of treatment.

  5. Un’architettura per e con le persone

    Directory of Open Access Journals (Sweden)

    Alessandro Rigolon

    2011-06-01

    Full Text Available L’articolo propone un approccio umanistico al progetto architettonico, ponendo le persone al centro del processo di concezione. Comprendere il modo in cui lo spazio influenza il comportamento, le emozioni e le attività delle persone dovrebbe essere il punto di partenza del progetto. Ciò implica una riflessione sui mezzi con i quali lo spazio trasmette significati connotativi e denotativi. Le tecniche per raccogliere informazioni dagli utenti e per includere tali informazioni nel progetto sono state analizzate per evidenziare i vantaggi e i problemi del mettere in pratica tale approccio umanistico. La discussione finale è focalizzata sulla possibile perdita di autonomia del progettista, sulla tempistica dell’introduzione dei dati derivati dagli utenti e sulle conseguenze dell’inclusione di tali dati nelle normali pratiche progettuali.

  6. Effects of ventilation rate per person and per floor area on perceived air quality, sick building syndrome symptoms, and decision-making.

    Science.gov (United States)

    Maddalena, R; Mendell, M J; Eliseeva, K; Chan, W R; Sullivan, D P; Russell, M; Satish, U; Fisk, W J

    2015-08-01

    Ventilation rates (VRs) in buildings must adequately control indoor levels of pollutants; however, VRs are constrained by the energy costs. Experiments in a simulated office assessed the effects of VR per occupant on perceived air quality (PAQ), Sick Building Syndrome (SBS) symptoms, and decision-making performance. A parallel set of experiments assessed the effects of VR per unit floor area on the same outcomes. Sixteen blinded healthy young adult subjects participated in each study. Each exposure lasted four hours and each subject experienced two conditions in a within-subject study design. The order of presentation of test conditions, day of testing, and gender were balanced. Temperature, relative humidity, VRs, and concentrations of pollutants were monitored. Online surveys assessed PAQ and SBS symptoms and a validated computer-based tool measured decision-making performance. Neither changing the VR per person nor changing the VR per floor area, had consistent statistically significant effects on PAQ or SBS symptoms. However, reductions in either occupant-based VR or floor-area-based VR had a significant and independent negative impact on most decision-making measures. These results indicate that the changes in VR employed in the study influence performance of healthy young adults even when PAQ and SBS symptoms are unaffected. The study results indicate the importance of avoiding low VRs per person and low VRs per floor area to minimize decrements in cognitive performance. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  7. Per Højholt - Auricula

    DEFF Research Database (Denmark)

    Hansen, Brian Benjamin

    2007-01-01

    ikke løftet sig”. Stilheden afsættes i de samlejer, der foregår i dette øjeblik, og 9 måneder efter nedkommer et større antal kvinder med både et barn og – paradoksalt nok – et løst øre! Sådan forløber den anekdote der indleder Per Højholts livsværk Auricula (latin for øre), skrevet i perioden 1978-2001....

  8. Documents hipertextuals per a entorns virtuals d'aprenentatge

    Directory of Open Access Journals (Sweden)

    Cristòfol Rovira

    1999-11-01

    Full Text Available L'article mostra les noves oportunitats que la Web d'Internet ha generat en el camp de la creació de documents hipertextuals. A partir de la grandària dels nodes, s'analitzen les característiques essencials del hipertextos d'abans de l'aparició de la Web per comparar-les amb les pàgines d'Internet. També es comenten les avantatges educatives que poden tenir aquest tipus de documents per entorns virtuals d'aprenentatge i finalment es presenta una proposta per escriure hipertextos basada en la grandària dels nodes.

  9. Strong sales growth in 2006: + 21 per cent

    International Nuclear Information System (INIS)

    2007-01-01

    Paris, February 14, 2007 - The Gaz de France group today reported record consolidated sales of euro 27,642 million in 2006, up 21 per cent compared with 2005. Under average weather conditions and comparable accounting methods, sales increased by 24 per cent versus 2005. This growth results primarily from an overall increase in European energy prices notwithstanding the slight decrease in prices towards the end of the year. The group also benefited from an increase in volumes and from the integration of new operations. After a colder first half of the year compared to that of the previous year, the autumn of 2006 was particularly warm. This had a negative impact on sales growth (there was a 12 billion kWh decrease between 2005 and 2006). The sales generated by the group's international activities increased by 33 per cent to a total of euro 10,839 m in 2006 and now account for almost 40 per cent of the group's overall sales. In this context, the group confirmed at the board meeting held on January 23, 2007 that it would reach the targets set for 2006, namely: - Growth in EBITDA above 20 per cent, e.g. in excess of euro 5 billion, - Net income of more than euro 2.2 billion

  10. Stochastic modeling for river pollution of Sungai Perlis

    International Nuclear Information System (INIS)

    Yunus, Nurul Izzaty Mohd.; Rahman, Haliza Abd.; Bahar, Arifah

    2015-01-01

    River pollution has been recognized as a contributor to a wide range of health problems and disorders in human. It can pose health dangers to humans who come into contact with it, either directly or indirectly. Therefore, it is most important to measure the concentration of Biochemical Oxygen Demand (BOD) as a water quality parameter since the parameter has long been the basic means for determining the degree of water pollution in rivers. In this study, BOD is used as a parameter to estimate the water quality at Sungai Perlis. It has been observed that Sungai Perlis is polluted due to lack of management and improper use of resources. Therefore, it is of importance to model the Sungai Perlis water quality in order to describe and predict the water quality systems. The BOD concentration secondary data set is used which was extracted from the Drainage and Irrigation Department Perlis State website. The first order differential equation from Streeter – Phelps model was utilized as a deterministic model. Then, the model was developed into a stochastic model. Results from this study shows that the stochastic model is more adequate to describe and predict the BOD concentration and the water quality systems in Sungai Perlis by having smaller value of mean squared error (MSE)

  11. Strong sales growth in 2006: + 21 per cent

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    Paris, February 14, 2007 - The Gaz de France group today reported record consolidated sales of euro 27,642 million in 2006, up 21 per cent compared with 2005. Under average weather conditions and comparable accounting methods, sales increased by 24 per cent versus 2005. This growth results primarily from an overall increase in European energy prices notwithstanding the slight decrease in prices towards the end of the year. The group also benefited from an increase in volumes and from the integration of new operations. After a colder first half of the year compared to that of the previous year, the autumn of 2006 was particularly warm. This had a negative impact on sales growth (there was a 12 billion kWh decrease between 2005 and 2006). The sales generated by the group's international activities increased by 33 per cent to a total of euro 10,839 m in 2006 and now account for almost 40 per cent of the group's overall sales. In this context, the group confirmed at the board meeting held on January 23, 2007 that it would reach the targets set for 2006, namely: - Growth in EBITDA above 20 per cent, e.g. in excess of euro 5 billion, - Net income of more than euro 2.2 billion.

  12. Stochastic modeling for river pollution of Sungai Perlis

    Energy Technology Data Exchange (ETDEWEB)

    Yunus, Nurul Izzaty Mohd.; Rahman, Haliza Abd. [Department of Mathematical Sciences, Faculty of Science, Universiti Teknologi Malaysia,81310 Johor Bahru, Johor (Malaysia); Bahar, Arifah [UTM-Centre of Industrial and Applied Mathematics (UTM-CIAM) Universiti Teknologi Malaysia, 81310 Johor Bahru, Johor (Malaysia)

    2015-02-03

    River pollution has been recognized as a contributor to a wide range of health problems and disorders in human. It can pose health dangers to humans who come into contact with it, either directly or indirectly. Therefore, it is most important to measure the concentration of Biochemical Oxygen Demand (BOD) as a water quality parameter since the parameter has long been the basic means for determining the degree of water pollution in rivers. In this study, BOD is used as a parameter to estimate the water quality at Sungai Perlis. It has been observed that Sungai Perlis is polluted due to lack of management and improper use of resources. Therefore, it is of importance to model the Sungai Perlis water quality in order to describe and predict the water quality systems. The BOD concentration secondary data set is used which was extracted from the Drainage and Irrigation Department Perlis State website. The first order differential equation from Streeter – Phelps model was utilized as a deterministic model. Then, the model was developed into a stochastic model. Results from this study shows that the stochastic model is more adequate to describe and predict the BOD concentration and the water quality systems in Sungai Perlis by having smaller value of mean squared error (MSE)

  13. MiniDLNA_tweaker : Aplicació per configurar i previsualitzar el servidor MiniDLNA per a GNU/Linux

    OpenAIRE

    Martínez Lloveras, Jordi

    2013-01-01

    L'aplicació MiniDLNA per a GNU/Linux és un servidor lleuger que compleix els estàndards DLNA/UPnP configurable a través d'un simple arxiu de text, això la fa ideal per al propòsit d'implantació d'un servidor que ofereixi els continguts a tots els dispositius que compleixin els estàndards esmentats. La aplicación MiniDLNA para GNU/Linux es un servidor ligero que cumple los estándares DLNA/UPnP configurable a través de un simple archivo de texto, esto la hace ideal para el propósito de impla...

  14. Impact of payment system change from per-case to per-diem on high severity patient's length of stay.

    Science.gov (United States)

    Jang, Sung-In; Nam, Chung Mo; Lee, Sang Gyu; Kim, Tae Hyun; Park, Sohee; Park, Eun-Cheol

    2016-09-01

    A new payment system, the diagnosis-related group (DRG) system, and Korean diagnosis procedure combination (KDPC, per-diem) payment system were officially introduced in 2002 and in 2012, respectively. We evaluated the impact of payment system change from per-case to per-diem on high severity patient's length of stay (LOS).Claim data was used. A total of 36,240 case admissions and 72,480 control admissions were included in the analysis. Segmented regression analysis of interrupted time series between cases and controls was conducted. Hospitals that consistently participated in the DRG payment system and changed to the KDPC payment system were defined as case hospitals. Hospitals that consistently participated in the DRG payment system were defined as control hospitals.LOS increased by 0.025 days per month (P = 0.0055) for 3 surgical diagnosis-related admissions due to the bundled payment system change. LOS among emergency admissions also increased and showed an increasing tendency under the KDPC. The LOS increase was observed specifically for complex procedure admissions and high severity cases (CCI 0, 1: 0.022, P = 0.0142; CCI 2, 3: 0.026, P = 0.0288; CCI ≥ 4: 0.055, P = 0.0003).Although both payment systems are optimized to decrease LOS, incentives to reduce LOS are stronger under the DRG system than under the KDPC system. It is worth noting that too strong incentive for reducing LOS is suitable to high severity cases.

  15. Entropy per baryon in a 'many-worlds' cosmology

    International Nuclear Information System (INIS)

    Clutton-Brock, M.

    1977-01-01

    The universe is imagined split into infinitely many branches, or 'worlds', only one of which can be observed. The world has an entropy per baryon xi approximately 10 9 : other worlds can have all possible values of entropy per baryon. High-entropy worlds with xi > 5x10 11 do not form galaxies, but only giant black holes. Low entropy worlds with xi 5 do form galaxies, but only metal-poor dwarf galaxies with no planets. Life can evolve only in worlds with entropy per baryon in the range 3x10 5 11 , and life is abundant only in a much narrower range. (Auth.)

  16. 38 CFR 61.33 - Payment of per diem.

    Science.gov (United States)

    2010-07-01

    ... United States, from departments of State and local governments, from private entities or organizations...) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.33 Payment of per diem. (a) A capital grant... non-grant recipient for those homeless veterans— (1) Who VA referred to the grant recipient or non...

  17. Tecniche integrate di rilievo per la comprensione di contesti archeologici e paesaggistici: note metodologiche per un approccio multi-scalare.

    Directory of Open Access Journals (Sweden)

    Giorgio Verdiani

    2017-12-01

    Full Text Available   Il patrimonio archeologico dell’area mediterranea è una delle manifestazioni più intense della volontà delle molte società che popolano questa zona fin dall’antichità. È un patrimonio culturale complesso e articolato che presenta enigmi difficili e possibilità impressionanti. Ciò crea la necessità di una comprensione accurata del soggetto della ricostruzione, delle sue connessioni e del suo contesto. In questo viaggio alla conoscenza, il “disegno” è il principale strumento di guida e operazione, dai primi schizzi al modello virtuale finale è il modo per scoprire le tracce della trama originale, la cosa per suggerire possibili soluzioni. Basando le sue considerazioni su dodici anni di indagini digitali e vari tentativi di ricostruzione digitale, questo contributo proporrà una discussione e definirà un percorso per questo tipo di procedure architettoniche specifiche nell’era digitale.

  18. Photoperiodic regulation of PER1 and PER2 protein expression in rat peripheral tissues

    Czech Academy of Sciences Publication Activity Database

    Bendová, Zdeňka; Sumová, Alena

    2006-01-01

    Roč. 55, č. 6 (2006), s. 623-632 ISSN 0862-8408 R&D Projects: GA ČR(CZ) GP309/02/D093; GA MŠk(CZ) LC554 Grant - others:EUCLOCK(XE) 018741 Institutional research plan: CEZ:AV0Z50110509 Keywords : circadian rhythms * peripheral tissue * PER proteins Subject RIV: FH - Neurology Impact factor: 2.093, year: 2006

  19. Wealth of the world's richest publicly traded companies per industry and per employee: Gamma, Log-normal and Pareto power-law as universal distributions?

    Science.gov (United States)

    Soriano-Hernández, P.; del Castillo-Mussot, M.; Campirán-Chávez, I.; Montemayor-Aldrete, J. A.

    2017-04-01

    Forbes Magazine published its list of leading or strongest publicly-traded two thousand companies in the world (G-2000) based on four independent metrics: sales or revenues, profits, assets and market value. Every one of these wealth metrics yields particular information on the corporate size or wealth size of each firm. The G-2000 cumulative probability wealth distribution per employee (per capita) for all four metrics exhibits a two-class structure: quasi-exponential in the lower part, and a Pareto power-law in the higher part. These two-class structure per capita distributions are qualitatively similar to income and wealth distributions in many countries of the world, but the fraction of firms per employee within the high-class Pareto is about 49% in sales per employee, and 33% after averaging on the four metrics, whereas in countries the fraction of rich agents in the Pareto zone is less than 10%. The quasi-exponential zone can be adjusted by Gamma or Log-normal distributions. On the other hand, Forbes classifies the G-2000 firms in 82 different industries or economic activities. Within each industry, the wealth distribution per employee also follows a two-class structure, but when the aggregate wealth of firms in each industry for the four metrics is divided by the total number of employees in that industry, then the 82 points of the aggregate wealth distribution by industry per employee can be well adjusted by quasi-exponential curves for the four metrics.

  20. GDP per capita since 1820

    NARCIS (Netherlands)

    Bolt, Jutta; Timmer, Marcel; van Zanden, Jan Luiten

    2014-01-01

    Since 1820, the world economy experienced spectacular growth in output and income. This chapter builds upon the work by Angus Maddison and shows that the world’s average GDP per capita increased by a factor of 10 between 1820 and the 2010. Yet, this growth was spread very unevenly, resulting in a

  1. Entropy per baryon in a 'many-worlds' cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Clutton-Brock, M [Manitoba Univ., Winnipeg (Canada)

    1977-04-01

    The universe is imagined split into infinitely many branches, or 'worlds', only one of which can be observed. The world has an entropy per baryon xi approximately 10/sup 9/: other worlds can have all possible values of entropy per baryon. High-entropy worlds with xi > 5x10/sup 11/ do not form galaxies, but only giant black holes. Low entropy worlds with xi < 3x10/sup 5/ do form galaxies, but only metal-poor dwarf galaxies with no planets. Life can evolve only in worlds with entropy per baryon in the range 3x10/sup 5/ < xi < 5x10/sup 11/, and life is abundant only in a much narrower range.

  2. Coronary calcium score as gatekeeper for 64-slice computed tomography coronary angiography in patients with chest pain: per-segment and per-patient analysis

    International Nuclear Information System (INIS)

    Palumbo, Anselmo Alessandro; Cademartiri, Filippo; Maffei, Erica; Martini, Chiara; Tarantini, Giuseppe; Di Tanna, Gian Luca; Berti, Elena; Grilli, Roberto; Casolo, Giancarlo; Brambilla, Valerio; Cerrato, Marcella; Rotondo, Antonio; Weustink, Annick C.; Mollet, Nico R.A.

    2009-01-01

    We sought to investigate the performance of 64-slice CT in symptomatic patients with different coronary calcium scores. Two hundred patients undergoing 64-slice CT coronary angiography for suspected coronary artery disease were enrolled into five groups based on Agatston calcium score using the Mayo Clinic risk stratification: group 1: score 0, group 2: score 1-10, group 3: score 11-100, group 4: score 101-400, and group 5: score > 401. Diagnostic accuracy for the detection of significant (≥50% lumen reduction) coronary artery stenosis was assessed on a per-segment and per-patient base using quantitative coronary angiography as the gold standard. For groups 1 through 5, sensitivity was 97, 96, 91, 90, 92%, and specificity was 99, 98, 96, 88, 90%, respectively, on a per-segment basis. On a per-patient basis, the best diagnostic performance was obtained in group 1 (sensitivity 100% and specificity 100%) and group 5 (sensitivity 95% and specificity 100%). Progressively higher coronary calcium levels affect diagnostic accuracy of CT coronary angiography, decreasing sensitivity and specificity on a per-segment base. On a per-patient base, the best results in terms of diagnostic accuracy were obtained in the populations with very low and very high cardiovascular risk. (orig.)

  3. Discharges with surgical procedures performed less often than once per month per hospital account for two-thirds of hospital costs of inpatient surgery.

    Science.gov (United States)

    O'Neill, Liam; Dexter, Franklin; Park, Sae-Hwan; Epstein, Richard H

    2017-09-01

    Most surgical discharges (54%) at the average hospital are for procedures performed no more often than once per month at that hospital. We hypothesized that such uncommon procedures would be associated with an even greater percentage of the total cost of performing all surgical procedures at that hospital. Observational study. State of Texas hospital discharge abstract data: 4th quarter of 2015 and 1st quarter of 2016. Inpatients discharged with a major therapeutic ("operative") procedure. For each of N=343 hospitals, counts of discharges, sums of lengths of stay (LOS), sums of diagnosis related group (DRG) case-mix weights, and sums of charges were obtained for each procedure or combination of procedures, classified by International Classification of Diseases version 10 Procedure Coding System (ICD-10-PCS). Each discharge was classified into 2 categories, uncommon versus not, defined as a procedure performed at most once per month versus those performed more often than once per month. Major procedures performed at most once per month per hospital accounted for an average among hospitals of 68% of the total inpatient costs associated with all major therapeutic procedures. On average, the percentage of total costs associated with uncommon procedures was 26% greater than expected based on their share of total discharges (Pcosts among surgical patients can be attributed to procedures performed at most once per month per hospital. The finding that such uncommon procedures account for a large percentage of costs is important because methods of cost accounting by procedure are generally unsuitable for them. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Estimation of optimal educational cost per medical student.

    Science.gov (United States)

    Yang, Eunbae B; Lee, Seunghee

    2009-09-01

    This study aims to estimate the optimal educational cost per medical student. A private medical college in Seoul was targeted by the study, and its 2006 learning environment and data from the 2003~2006 budget and settlement were carefully analyzed. Through interviews with 3 medical professors and 2 experts in the economics of education, the study attempted to establish the educational cost estimation model, which yields an empirically computed estimate of the optimal cost per student in medical college. The estimation model was based primarily upon the educational cost which consisted of direct educational costs (47.25%), support costs (36.44%), fixed asset purchases (11.18%) and costs for student affairs (5.14%). These results indicate that the optimal cost per student is approximately 20,367,000 won each semester; thus, training a doctor costs 162,936,000 won over 4 years. Consequently, we inferred that the tuition levels of a local medical college or professional medical graduate school cover one quarter or one-half of the per- student cost. The findings of this study do not necessarily imply an increase in medical college tuition; the estimation of the per-student cost for training to be a doctor is one matter, and the issue of who should bear this burden is another. For further study, we should consider the college type and its location for general application of the estimation method, in addition to living expenses and opportunity costs.

  5. Playware e robotica modulare per il gioco

    Directory of Open Access Journals (Sweden)

    Henrik H. Lund

    2009-01-01

    Full Text Available In questo contributo presentiamo e usiamo il concetto di building block robotico per la creazione di playware. Il concetto tecnologico di building block programmabili e dotati di input e output (ivi inclusa la comunicazione e dell'intelligenza artificiale embodied, che enfatizza la relazione fra morfologia e controllo.Per dare un esempio concreto del concetto di building block robotico, proponiamo le mattonelle che abbiamo creato, come elementi che compongono un nuovo tipo di campo giochi sul quale i bambini possono sperimentare un feedback immediato ai loro movimenti.

  6. Energy metrics for driving competitiveness of countries: Energy weakness magnitude, GDP per barrel and barrels per capita

    International Nuclear Information System (INIS)

    Coccia, Mario

    2010-01-01

    Energy metrics is the development of a whole new theoretical framework for the conception and measurement of energy and economic system performances, energy efficiency and productivity improvements with important political economy implications consistent with the best use of all natural and economic resources. The purpose of this research is to present some vital energy indicators based on magnitude and scale of energy weakness, GDP per barrel of oil that is an indicator of energy productivity and barrels (of oil) per capita that is an indicator of energy efficiency. Energy metrics can support the monitoring of energy and economic system performances in order to design effective energy strategy and political economy interventions focused on the 'competitive advantage' increase of countries in modern economies.

  7. PER PhDs & Bachelor's Degrees

    Science.gov (United States)

    White, Susan C.

    2017-01-01

    Recently, the editor remarked to me that physics departments that offered a PhD with a specialization in Physics Education Research (PER) seemed to graduate more bachelor's degree recipients than those physics PhD departments that did not have the specialization. I was not convinced. That led to quite a bit of discussion between us. He compiled a…

  8. KPNB1 mediates PER/CRY nuclear translocation and circadian clock function.

    Science.gov (United States)

    Lee, Yool; Jang, A Reum; Francey, Lauren J; Sehgal, Amita; Hogenesch, John B

    2015-08-29

    Regulated nuclear translocation of the PER/CRY repressor complex is critical for negative feedback regulation of the circadian clock of mammals. However, the precise molecular mechanism is not fully understood. Here, we report that KPNB1, an importin β component of the ncRNA repressor of nuclear factor of activated T cells (NRON) ribonucleoprotein complex, mediates nuclear translocation and repressor function of the PER/CRY complex. RNAi depletion of KPNB1 traps the PER/CRY complex in the cytoplasm by blocking nuclear entry of PER proteins in human cells. KPNB1 interacts mainly with PER proteins and directs PER/CRY nuclear transport in a circadian fashion. Interestingly, KPNB1 regulates the PER/CRY nuclear entry and repressor function, independently of importin α, its classical partner. Moreover, inducible inhibition of the conserved Drosophila importin β in lateral neurons abolishes behavioral rhythms in flies. Collectively, these data show that KPNB1 is required for timely nuclear import of PER/CRY in the negative feedback regulation of the circadian clock.

  9. [Cost per capita in outpatients by gender].

    Science.gov (United States)

    Villarreal-Ríos, Enrique; Campos Esparza, Maribel; Galicia Rodríguez, Liliana; Martínez González, Lidia; Vargas Daza, Emma Rosa; Torres Labra, Guadalupe; Patiño Vega, Adolfo; Rivera Martínez, María Teresa; Aparicio Rojas, Raúl; Juárez Durán, Martín

    2011-03-01

    The objective of this study is to identify the annual cost per capita by gender in first level of attention. It is a cost study in Family Physician Units in Mexico. The information corresponded to the year of 2004 and the study divided in the use profile and cost attention. USE PROFILE OF SERVICES: it was studied 1,585 clinical registries of patients, use profile defined by average and attention reasons by department, gender and age group. COST ATTENTION: considered in American dollars it included fixed unit cost (departmentalization adjusted by productivity), variable unit cost (micro cost technical), department unite cost by type attention, and department unit cost by age and gender. The life expectancy was of 73 years for men and 78 for women. Three scenes were identified. The annual cost per capita is superior among woman [US$73.24 (IC 95% $11.38 - $197.49)] than in man [$ 53.11 (IC 95% 2.51 - 207.71)]. The conclusion found that in the first level of attention the cost per capita is greater in woman than in man.

  10. Cooperar per ensenyar, aprendre de forma cooperativa

    Directory of Open Access Journals (Sweden)

    Raúl García-Medina

    2015-07-01

    Full Text Available La següent experiència sorgeix de la inquietud dels autors per aconseguir una coherència més gran entre el seu discurs pedagògic (aprenentatge cooperatiu, pedagogia crítica... i la pràctica educativa en la formació dels futurs docents i educadors. Lamentablement, aquesta pràctica és desvirtuada per les nombroses barreres estructurals que oposa el context institucional: individualisme i aïllament docents, competitivitat, fragmentació curricular... Per aconseguir-ho, es va intentar transformar cada grup d'estudiants en una comunitat d'aprenentatge, fomentant la seva implicació i participació per tal  de que poguessin integrar el coneixement acadèmic amb el coneixement social o interaccional, descobrir el valor de la reflexió sobre la pràctica i desenvolupar co-responsabilitat a l'aprenentatge. En definitiva, es tractava d’establir corrents dialògiques entre les subjectivitats  de cada alumne, i entre aquests i els professors.En avaluar l'experiència vàrem poder constatar un increment de l'atenció sostinguda durant tot el curs, al trencar amb el costum de confiar l’avaluació a l’esforç final davant  l’examen, així com una més sòlida cohesió de grup que va afavorir la interacció, l’intercanvi de coneixements i la col·laboració. Al mateix temps, els propis autors van poder experimentar una major satisfacció professional, intel·lectual i emocional.

  11. The dependence of radiation response on the dose per fraction

    International Nuclear Information System (INIS)

    Joiner, M.C.

    1989-01-01

    The linear-quadratic (LQ) model explains the dependence of total dose in a fractionated course on the dose per fraction, in a very wide range of tumour and normal tissue studies, providing the dose per fraction remains above 2 Gy. In the range 2-1 Gy per fraction, some experimental studies show less increase in total dose than predicted by LQ; a probable explanation is incomplete repair between fractions given 2 seen between 1 and 0.1 Gy per fraction. This cannot be explained by incomplete repair; a modified LQ model where α decreases sharply with increasing dose per fraction in the range 0-1 Gy fits these data. The basic LQ model describes data from neutron fractionation studies, so the relationship between relative biological effectiveness (RBE) and X-ray dose per fraction can be expressed in terms of LQ parameters and fitted directly to RBE data. Results from different experiments, different assays and both top-up and full-course fractionation techniques, can all be included in one analysis. (author)

  12. Planeamiento estratégico de Perú

    OpenAIRE

    Díaz Huamán, Denis Katia; Giraldo Chávez, Elio César; Miranda Aragón, Abraham Roberto; Peralta Morales, Rolando Dionel; Tintaya Jacya, Hugo

    2017-01-01

    xv, 144 h. : il. ; 30 cm. Se ha desarrollado el planeamiento estratégico para el Perú, utilizando la metodología denominada Proceso Estratégico y que fue creada por D’Alessio (2015). Este país se encuentra ubicado en el centro occidente de América del Sur, con acceso a importantes mercados de Asia y de América Latina, así como a Estados Unidos. El Perú está organizado en 24 regiones y una provincia constitucional, que a su vez se dividen en provincias y distritos, albergando...

  13. Apiaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Apiaceae es reconocida en el Perú por presentar 29 géneros y 88 especies (Brako & Zarucchi, 1993, básicamente hierbas y subarbustos. En este trabajo reconocemos como endémicos 22 taxones en siete géneros. Un género, Paraselinum, es endémico del Perú. La mayoría de los taxones endémicos ocupan las regiones Desierto Semicálido Costero, Mesoandina y Bosques Muy Húmedos Montanos, entre los 10 y 4400 m de altitud. Ninguna de estas especies está representada en las áreas protegidas.

  14. ANTIHEPATOTOXIC ACTIVITY OF ECLIPTA ALBA, TEPHROSIA PURPUREA AND BOERHAAVIA DIFFUSA

    Science.gov (United States)

    Murthy, V. N.; Reddy, B. Praveen; Venkateshwarlu, V.; Kokate, C. K.

    1992-01-01

    Alcoholic and chloroform extracts of E. alba T. purpurea and B. diffusa were screened for antihepatotoxic activity. The extracts were given after the liver was damaged with CCl4. Liver function was assessed based on liver to boy weight ratio, pentobarbitone sleep time, serum levels of transaminase (SGPT, SGOT), alkaline phosphatase (SALP) and bilirubin. Alcoholic extract of E. alba was found to have good antihepatotoxic activity. PMID:22556585

  15. Circadian clock genes Per1 and Per2 regulate the response of metabolism-associated transcripts to sleep disruption.

    Directory of Open Access Journals (Sweden)

    Jana Husse

    Full Text Available Human and animal studies demonstrate that short sleep or poor sleep quality, e.g. in night shift workers, promote the development of obesity and diabetes. Effects of sleep disruption on glucose homeostasis and liver physiology are well documented. However, changes in adipokine levels after sleep disruption suggest that adipocytes might be another important peripheral target of sleep. Circadian clocks regulate metabolic homeostasis and clock disruption can result in obesity and the metabolic syndrome. The finding that sleep and clock disruption have very similar metabolic effects prompted us to ask whether the circadian clock machinery may mediate the metabolic consequences of sleep disruption. To test this we analyzed energy homeostasis and adipocyte transcriptome regulation in a mouse model of shift work, in which we prevented mice from sleeping during the first six hours of their normal inactive phase for five consecutive days (timed sleep restriction--TSR. We compared the effects of TSR between wild-type and Per1/2 double mutant mice with the prediction that the absence of a circadian clock in Per1/2 mutants would result in a blunted metabolic response to TSR. In wild-types, TSR induces significant transcriptional reprogramming of white adipose tissue, suggestive of increased lipogenesis, together with increased secretion of the adipokine leptin and increased food intake, hallmarks of obesity and associated leptin resistance. Some of these changes persist for at least one week after the end of TSR, indicating that even short episodes of sleep disruption can induce prolonged physiological impairments. In contrast, Per1/2 deficient mice show blunted effects of TSR on food intake, leptin levels and adipose transcription. We conclude that the absence of a functional clock in Per1/2 double mutants protects these mice from TSR-induced metabolic reprogramming, suggesting a role of the circadian timing system in regulating the physiological effects

  16. PDF and cAMP enhance PER stability in Drosophila clock neurons

    Science.gov (United States)

    Li, Yue; Guo, Fang; Shen, James; Rosbash, Michael

    2014-01-01

    The neuropeptide PDF is important for Drosophila circadian rhythms: pdf01 (pdf-null) animals are mostly arrhythmic or short period in constant darkness and have an advanced activity peak in light–dark conditions. PDF contributes to the amplitude, synchrony, as well as the pace of circadian rhythms within clock neurons. PDF is known to increase cAMP levels in PDR receptor (PDFR)-containing neurons. However, there is no known connection of PDF or of cAMP with the Drosophila molecular clockworks. We discovered that the mutant period gene perS ameliorates the phenotypes of pdf-null flies. The period protein (PER) is a well-studied repressor of clock gene transcription, and the perS protein (PERS) has a markedly short half-life. The result therefore suggests that the PDF-mediated increase in cAMP might lengthen circadian period by directly enhancing PER stability. Indeed, increasing cAMP levels and cAMP-mediated protein kinase A (PKA) activity stabilizes PER, in S2 tissue culture cells and in fly circadian neurons. Adding PDF to fly brains in vitro has a similar effect. Consistent with these relationships, a light pulse causes more prominent PER degradation in pdf01 circadian neurons than in wild-type neurons. The results indicate that PDF contributes to clock neuron synchrony by increasing cAMP and PKA, which enhance PER stability and decrease clock speed in intrinsically fast-paced PDFR-containing clock neurons. We further suggest that the more rapid degradation of PERS bypasses PKA regulation and makes the pace of clock neurons more uniform, allowing them to avoid much of the asynchrony caused by the absence of PDF. PMID:24707054

  17. Per-point and per-field contextual classification of multipolarization and multiple incidence angle aircraft L-band radar data

    Science.gov (United States)

    Hoffer, Roger M.; Hussin, Yousif Ali

    1989-01-01

    Multipolarized aircraft L-band radar data are classified using two different image classification algorithms: (1) a per-point classifier, and (2) a contextual, or per-field, classifier. Due to the distinct variations in radar backscatter as a function of incidence angle, the data are stratified into three incidence-angle groupings, and training and test data are defined for each stratum. A low-pass digital mean filter with varied window size (i.e., 3x3, 5x5, and 7x7 pixels) is applied to the data prior to the classification. A predominately forested area in northern Florida was the study site. The results obtained by using these image classifiers are then presented and discussed.

  18. Local sensitivity of per-recruit fishing mortality reference points.

    Science.gov (United States)

    Cadigan, N G; Wang, S

    2016-12-01

    We study the sensitivity of fishery management per-recruit harvest rates which may be part of a quantitative harvest strategy designed to achieve some objective for catch or population size. We use a local influence sensitivity analysis to derive equations that describe how these reference harvest rates are affected by perturbations to productivity processes. These equations give a basic theoretical understanding of sensitivity that can be used to predict what the likely impacts of future changes in productivity will be. Our results indicate that per-recruit reference harvest rates are more sensitive to perturbations when the equilibrium catch or population size per recruit, as functions of the harvest rate, have less curvature near the reference point. Overall our results suggest that per recruit reference points will, with some exceptions, usually increase if (1) growth rates increase, (2) natural mortality rates increase, or (3) fishery selectivity increases to an older age.

  19. Ligeti: Ricercare per organo / M. K.

    Index Scriptorium Estoniae

    M. K.

    1991-01-01

    Uuest heliplaadist "Ligeti: Ricercare per organo, Vivier, Les Communiantes, Cavana, Jodl; Scelsi: In nomine Lucis; Lennot: Livre d'Orgue-extrait; Richer: Orgue 88; Pärt: Pari intervallo, Pierre Bousseau (Orgel)" (AD:1990). Adda/TIS CD 581 240 (WD:59'45") DDD

  20. CALiPER Retail Lamps Study 3

    Energy Technology Data Exchange (ETDEWEB)

    Royer, Michael P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Beeson, Tracy A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-02-01

    The CALiPER program first began investigating LED lamps sold at retail stores in 2010, purchasing 33 products from eight retailers and covering six product categories. The findings revealed a fragmented marketplace, with large disparities in performance of different products, accuracy of manufacturer claims, and offerings from different retail outlets. Although there were some good products, looking back many would not be considered viable competitors to other available options, with too little lumen output, not high enough efficacy, or poor color quality. CALiPER took another look in late 2011purchasing 38 products of five different types from nine retailers and the improvement was marked. Performance was up; retailer claims were more accurate; and the price per lumen and price per unit efficacy were down, although the price per product had not changed much. Nonetheless, there was still plenty of room for improvement, with the performance of LED lamps not yet reaching that of well-established classes of conventional lamps (e.g., 75 W incandescent A19 lamps). Since the second retail lamp study was published in early 2012, there has been substantial progress in all aspects of LED lamps available from retailers. To document this progress, CALiPER again purchased a sample of lamps from retail stores 46 products in total, focusing on A19, PAR30, and MR16 lamps but instead of a random sample, sought to select products to answer specific hypotheses about performance. These hypotheses focused on expanding ranges of LED equivalency, the accuracy of lifetime claims, efficacy and price trends, as well as changes to product designs. Among other results, key findings include: There are now very good LED options to compete with 60 W, 75 W, and 100 W incandescent A19 lamps, and 75 W halogen PAR30 lamps. MR16 lamps have shown less progress, but there are now acceptable alternatives to 35 W, 12 V halogen MR16 lamps and 50 W, 120 V halogen MR16 lamps for some applications. Other

  1. Cost per responder of TNF-α therapies in Germany.

    Science.gov (United States)

    Gissel, Christian; Repp, Holger

    2013-12-01

    Tumor necrosis factor α (TNF-α) inhibitors ranked highest in German pharmaceutical expenditure in 2011. Their most important application is the treatment of rheumatoid arthritis (RA). Our objective is to analyze cost per responder of TNF-α inhibitors for RA from the German Statutory Health Insurance funds' perspective. We aim to conduct the analysis based on randomized comparative effectiveness studies of the relevant treatments for the German setting. For inclusion of effectiveness studies, we require results in terms of response rates as defined by European League Against Rheumatism (EULAR) or American College of Rheumatology (ACR) criteria. We identify conventional triple therapy as the relevant comparator. We calculate cost per responder based on German direct medical costs. Direct clinical comparisons could be identified for both etanercept and infliximab compared to triple therapy. For infliximab, cost per responder was 216,392 euros for ACR50 and 432,784 euros for ACR70 responses. For etanercept, cost per ACR70 responder was 321,527 euros. Cost was lower for response defined by EULAR criteria, but data was only available for infliximab. Cost per responder is overestimated by 40% due to inclusion of taxes and mandatory rebates in German drugs' list prices. Our analysis shows specific requirements for cost-effectiveness analysis in Germany. Cost per responder for TNF-α treatment in the German setting is more than double the cost estimated in a similar analysis for the USA, which measured against placebo. The difference in results shows the critical role of the correct comparator for a specific setting.

  2. Empirical estimation of per capita brandy demand in Armenia

    Directory of Open Access Journals (Sweden)

    S.A. Movsisyan

    2017-03-01

    Full Text Available The empirical estimations were based on linear and double-log regression models, which identified the factors influencing the average per capita brandy demand in Armenia. The model was estimated using quarterly time-series data on per capita brandy consumption, disposable income, prices of various alcoholic beverages for 1997–2015 periods. This is quantitative study based on secondary annual, quarterly and monthly data, and 5% significance level. The average annual per capita brandy consumption data for 1997–2007 periods was obtained from WHO's website, whereas the 2008–2015 data was extracted from the National Statistical Service of the Republic of Armenia. For annual, quarterly and monthly periods from 1997 through 2015, the price data related to various alcoholic beverages, consumer price index were provided in NSS statistical publications of “Socio-Economic Situation of RA”, ”Consumer price indexes (prices in the Republic of Armenia”, “Prices and tariffs in the Republic of Armenia”. For 1997–2015 periods, the average monthly per capita monetary income data was obtained from “Living Standards of Population and Social Sphere” section of statistical yearbooks. The latter substituted the average per capita monthly disposable income data, since these data were unavailable. Meantime, since the data included numerous years, therefore, the nominal price and income data were adjusted for inflation using consumer price index with 2005 as base year. In conclusion, the average real prices of wine and vodka were statistically significant determinants of the average per capita brandy demand in Armenia, and the demand for brandy was inelastic.

  3. Una nuova piattaforma per i Dati Aperti

    Directory of Open Access Journals (Sweden)

    Ernesto Lastres

    2013-02-01

    Full Text Available In un panorama di continua evoluzione ed interesse da parte della opinione pubblica sul tema dei “dati open” moltienti della pubblica amministrazione e di governo stanno svolgendo azioni specifiche per la concretizzazione di queste iniziative in ottica di open government. Tuttavia, sono in pochi quelli che nel settore privato hanno intrapreso delle iniziative importanti in tale direzione. In questo articolo presentiamo una iniziativa indipendente per una nuova piattaforma software dedicata ai dati open su internet che, se confermasse i propri scopi, costituirebbe un punto di partenza a livello nazionale per l’accesso a questi dati.In a very evolving context and in a particular moment of public interest in theme of open data, many public organizations and government institutions are carrying out specific actions for the realization of initiatives in order to promote the open government ideas. However, very few private organizations have launched initiatives in this direction. In this paper we present an independent initiative for a new software platform for opendata on the internet that aims to be a starting point at the national level for the access to these kind of data.

  4. Una nuova piattaforma per i Dati Aperti

    Directory of Open Access Journals (Sweden)

    Ernesto Lastres

    2013-02-01

    Full Text Available In un panorama di continua evoluzione ed interesse da parte della opinione pubblica sul tema dei “dati open” moltienti della pubblica amministrazione e di governo stanno svolgendo azioni specifiche per la concretizzazione di queste iniziative in ottica di open government. Tuttavia, sono in pochi quelli che nel settore privato hanno intrapreso delle iniziative importanti in tale direzione. In questo articolo presentiamo una iniziativa indipendente per una nuova piattaforma software dedicata ai dati open su internet che, se confermasse i propri scopi, costituirebbe un punto di partenza a livello nazionale per l’accesso a questi dati. In a very evolving context and in a particular moment of public interest in theme of open data, many public organizations and government institutions are carrying out specific actions for the realization of initiatives in order to promote the open government ideas. However, very few private organizations have launched initiatives in this direction. In this paper we present an independent initiative for a new software platform for opendata on the internet that aims to be a starting point at the national level for the access to these kind of data.

  5. Obituary: Per E. Maltby, 1933-2006

    Science.gov (United States)

    Kjeldseth-Moe, Olav

    2007-12-01

    Professor Per Maltby, prominent Norwegian Solar Physicist at the Institute of Theoretical Astrophysics, University of Oslo, Norway, died on 24 May 2006. Lung cancer was diagnosed in February, but he was expected to improve. Until the end of March he came to his office every day, got recent papers off the web, and followed his field closely as he had always done. Per Maltby was born in Oslo, Norway, on 3 November 1933. He started his studies at the University of Oslo in 1952 and took his candidate degree in 1957. Between 1955 and 1958 he was a research assistant at the Institute of Theoretical Astrophysics in Oslo. In 1960 Maltby became an assistant professor (amanuensis) at the University of Bergen and from January 1963 he held a corresponding position at the University of Oslo. He became an associate professor in 1967, and from 1983 until he retired in 2003 he was a full Professor at the Institute of Theoretical Astrophysics, University of Oslo. Per Maltby is survived by his wife Elisabet (née Ruud), whom he married in 1956. They had two children. The daughter, Bente, is a medical doctor and gynecologist serving as a section head at the district hospital in Kristiansand in southern Norway. Their son, Lars, holds a doctoral degree in engineering, specializing in the properties of powders. He is currently managing director in the Norwegian division of the French multinational company Saint Gobain. As a father Per Maltby expressed pride in his children and was pleased with their progress in life. He also enjoyed his five grandchildren. As a scientist, Per Maltby was versatile and productive. In the early 1960s he visited the California Institute of Technology where he did pioneering studies of the distribution and time variation of the radio emission from active galaxies, using the Owens Valley Radio Observatory. His work with Alan Moffet contributed to revealing the secrets of these remote objects. Their results drew attention and were indeed mentioned in the pages

  6. Optimized Cost per Click in Taobao Display Advertising

    OpenAIRE

    Zhu, Han; Jin, Junqi; Tan, Chang; Pan, Fei; Zeng, Yifan; Li, Han; Gai, Kun

    2017-01-01

    Taobao, as the largest online retail platform in the world, provides billions of online display advertising impressions for millions of advertisers every day. For commercial purposes, the advertisers bid for specific spots and target crowds to compete for business traffic. The platform chooses the most suitable ads to display in tens of milliseconds. Common pricing methods include cost per mille (CPM) and cost per click (CPC). Traditional advertising systems target certain traits of users and...

  7. Characterization of (per)chlorate-reducing bacteria

    NARCIS (Netherlands)

    Wolterink, A.F.W.M.

    2004-01-01

    Some bacteria can use (per)chlorateas terminal electron acceptor for growth. These bacteria convert perchlorate via chlorate and chlorite into chloride and molecular oxygen. Oxygen formation in microbial respiration is unique. In this study two chlorate-reducing strains

  8. Performance evaluation of the Personal Mobility and Manipulation Appliance (PerMMA).

    Science.gov (United States)

    Wang, Hongwu; Xu, Jijie; Grindle, Garrett; Vazquez, Juan; Salatin, Ben; Kelleher, Annmarie; Ding, Dan; Collins, Diane M; Cooper, Rory A

    2013-11-01

    The Personal Mobility and Manipulation Appliance (PerMMA) is a recently developed personal assistance robot created to provide people with severe physical disabilities enhanced assistance in both mobility and manipulation. PerMMA aims to improve functional independence when a personal care attendant is not available on site. PerMMA integrates both a smart powered wheelchair and two dexterous robotic arms to assist its users in completing essential mobility and manipulation tasks during basic and instrumental activities of daily living (ADL). Two user interfaces were developed: a local control interface and a remote operator controller. This paper reports on the evaluation of PerMMA with end users completing basic ADL tasks. Participants with both lower and upper extremity impairments (N=15) were recruited to operate PerMMA and complete up to five ADL tasks in a single session of no more than two hours (to avoid fatigue or frustration of the participants). The performance of PerMMA was evaluated by participants completing ADL tasks with two different control modes: local mode and cooperative control. The users' task completion performance and answers on pre/post-evaluation questionnaires demonstrated not only the ease in learning and usefulness of PerMMA, but also their attitudes toward assistance from advanced technology like PerMMA. As a part of the iterative development process, results of this work will serve as supporting evidence to identify design criteria and other areas for improvement of PerMMA. Copyright © 2013 IPEM. All rights reserved.

  9. CityLog, verso nuove soluzioni per la distribuzione urbana delle merci

    Directory of Open Access Journals (Sweden)

    Saverio Zuccotti

    2010-07-01

    Full Text Available La logistica urbana rappresenta oggi una delle principali sfide per una mobilità sostenibile. La distribuzione delle merci in città paga infatti in competitività quei problemi di cui è in parte responsabile: traffico, inquinamento, incidenti etc. Negli ultimi anni la sensibilità su questi aspetti di sostenibilità ambientale è cresciuta in maniera netta, e a livello europeo molta strada è stata fatta per predisporre le risposte più adeguate. Il progetto europeo CityLog, finanziato nell’ambito del Settimo Programma Quadro, vede oggi collaborare diciotto partner europei coordinati dal Centro Ricerche Fiat per migliorare la logistica urbana agendo lungo tre direttrici: •\tservizi telematici orientati alla logistica, per dare un contributo decisivo al miglioramento della pianificazione delle missioni utilizzando strumenti per il routing ottimizzato dei veicoli e il supporto informativo costante agli autisti dei veicoli; •\tsoluzioni a bordo veicolo, che rappresentano un fattore chiave per aumentare la flessibilità operativa di camion e furgoni; •\tunità di carico innovative, accuratamente progettate per essere utilizzate su veicoli diversi in missioni diverse. Ne deriva pertanto una famiglia di container compatti con un layout interno riconfigurabile così da poter essere utilizzati per scopi diversi.

  10. Do changes in per capita consumption mirror changes in drinking patterns?

    Science.gov (United States)

    Smart, R G; Suurvali, H M; Mann, R E

    2000-07-01

    The goal of this study was to examine how well per capita alcohol consumption figures derived from beverage sales data relate to changes over time in survey-based measures of drinking patterns. It was expected that strong associations would be found among these various measures of consumption. Data from 12 household surveys conducted in Ontario between 1977 and 1997 provided information on: percentages of drinkers; daily drinkers; those drinking five or more drinks at a sitting weekly; those reporting two or more alcohol-related harms; and average number of drinks per week. These variables were then correlated with per capita consumption. Significant correlations were found only between per capita consumption and percentage of daily drinkers, and between percentage of drinkers and average number of drinks per week. The relationship of per capita consumption to survey measures of drinking is weak. The absence of consistent associations over time between per capita consumption and survey measures may be attributable to the small number of available data points or to increases in unrecorded consumption. Further research is needed to verify and explain these results.

  11. 28 CFR 0.142 - Per diem and travel allowances.

    Science.gov (United States)

    2010-07-01

    ... authorized to approve travel expenses of newly appointed special agents and the transportation expenses of... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Per diem and travel allowances. 0.142... Authorizations With Respect to Personnel and Certain Administrative Matters § 0.142 Per diem and travel...

  12. Saving assessment using the PERS in solar power towers

    International Nuclear Information System (INIS)

    Rodriguez-Sanchez, M.R.; Sanchez-Gonzalez, A.; Marugan-Cruz, C.; Santana, D.

    2014-01-01

    Highlights: • The lamination of the solar salt is avoided using the PERS and the main energy sink. • The PERS using salt pump as turbine saves 30–50% of the parasitic power. • The most appropriate configuration is a similar turbine three times one salt pump. • The payback period is around two years, and the economical savings from 1 to 4 M$. - Abstract: The improvement of the solar power tower using solar salt is one of the main goals of researchers. Any method or invention to improve the efficiency of this technology contributes to promote the renewable energies. The use of a Potential Energy Recovery System (PERS) in two different solar power tower plants of 20 and 100 MW has been analysed. The PERS is formed, at least, by one turbine, located at the hot salt pipe coming from the receiver. The turbine is engaged to the shaft of the feed pump, which raises the heat transfer fluid from the cold tank to the receiver. It reduces the parasitic power consumption of the plant, and increases its global efficiency. Different PERS configurations have been modelled. Based on an energetic and economic analysis, the optimal configuration is a geometrical similar turbine of three times the volume flow rate of one feed pump. The PERS has been proven to be a cost reductive and clean tool. For a 100 MW power plant of 30-year lifetime the investment cost is 1.26 M$ and the annual cash flow is 0.89 M$, while for a plant of 20 MW these values are 0.26 M$ and 0.19 M$, respectively

  13. Per Diems in Polio Eradication: Perspectives From Community Health Workers and Officials.

    Science.gov (United States)

    Closser, Svea; Rosenthal, Anat; Justice, Judith; Maes, Kenneth; Sultan, Marium; Banerji, Sarah; Amaha, Hailom Banteyerga; Gopinath, Ranjani; Omidian, Patricia; Nyirazinyoye, Laetitia

    2017-09-01

    Nearly all global health initiatives give per diems to community health workers (CHWs) in poor countries for short-term work on disease-specific programs. We interviewed CHWs, supervisors, and high-level officials (n = 95) in 6 study sites across sub-Saharan Africa and South Asia in early 2012 about the per diems given to them by the Global Polio Eradication Initiative. These per diems for CHWs ranged from $1.50 to $2.40 per day. International officials defended per diems for CHWs with an array of arguments, primarily that they were necessary to defray the expenses that workers incurred during campaigns. But high-level ministry of health officials in many countries were concerned that even small per diems were unsustainable. By contrast, CHWs saw per diems as a wage; the very small size of this wage led many to describe per diems as unjust. Per diem polio work existed in the larger context of limited and mostly exploitative options for female labor. Taking the perspectives of CHWs seriously would shift the international conversation about per diems toward questions of labor rights and justice in global health pay structures.

  14. 10 volti per la Liberazione. Una mostra per le strade della città

    Directory of Open Access Journals (Sweden)

    Margherita Becchetti

    2013-09-01

    Full Text Available Nel saggio si dà conto delle vicende che hanno segnato “10 volti per la Liberazione”, mostra diffusa nelle strade di Parma, allestita in occasione del 25 aprile 2013 dal Centro studi movimenti con sagome a grandezza naturale di alcuni protagonisti della lotta partigiana. L’autrice affronta i problemi incontrati nel corso dell’allestimento e le reazioni che l’iniziativa ha suscitato, elementi che investono direttamente la riflessione storiografica avendo a che vedere con l’uso pubblico della storia, con il rapporto tra memoria pubblica e privata e con il ruolo rivestito dagli storici nella costruzione della memoria collettiva.

  15. HiPER: The European path to laser energy

    Directory of Open Access Journals (Sweden)

    Edwards Chris

    2013-11-01

    Full Text Available While for decades, energy production relying on laser inertial fusion has been a strong motivation for the development in Europe of a few high-energy laser facilities and dedicated scientific programs, the HiPER initiative launched in 2004 fostered an ambitious large-scale coordinated European program toward inertial fusion energy. Anticipating the successful demonstration of fusion ignition and gain at the National Ignition Facility (NIF in the USA, scientists and engineers from across Europe are developing the case for a next generation laser fusion facility, HiPER, to be constructed in Europe. The single-facility build strategy of HiPER (High Power Laser Energy Research Facility aims at first demonstrating some key elements of a fusion reactor in a high rep-rate few-second cycle mode, before addressing energy production on a high rep-rate continuous mode in a second area.

  16. A Mathematical model to predict the US Airlines operation costs and airports charges per route per passenger

    NARCIS (Netherlands)

    Carmona Benitez, R.B.; Lodewijiks, G.

    2010-01-01

    A mathematical model to estimate the average airlines operational costs and airports charges per route is important for airlines companies trying to open new routes and for data generation for other purpose such as transport modeling, simulation modeling, investment analyses for airlines and

  17. UN’APPLICAZIONE ARCGIS PER LA SICUREZZA DEL COSTRUITO

    Directory of Open Access Journals (Sweden)

    Luigi Colombo

    2013-08-01

    Full Text Available La difesa delle città da eventi naturali, come i terremoti, richiede sia il miglioramento delle qualità costruttive degli edifici, sia la riduzione consistente della loro danneggiabilità. Questi requisiti sono conseguibili, per gli edifici di nuova costruzione, attraverso l’applicazione della normativa anti-simica, e, per quelli esistenti, utilizzando strumenti che si basano su un’attenta classificazione della predisposizione al danneggiamento (vulnerabilità, sia per l’aspetto costruttivo sia per quello strutturale, materico e geo-ambientale. The Italian land has a great amount of both ancient outstanding buildings and modern ones. Nowadays, risk evaluation and analysis are extremely useful to prevent the dangerous natural calamities, which have always been happening in Italy, involving both human lives and structures maintenance. This is a very complex problem which requires a wide knowledge concerning structural, material and territorial information: a GIS system could be the effective instrument able to automatize analysis processes, to provide thematic outputs and to help the users in operational choices and online analyses. The paper deals with a GIS application in the little town of Verdellino, close to Bergamo, which has been developed carrying out a detailed geo-database for seismic buildings classification. The experience has proved the meaningful role of informatics instruments in visualization, risk classification and in pre/ post events management for a more general safeguard.

  18. UN’APPLICAZIONE ARCGIS PER LA SICUREZZA DEL COSTRUITO

    Directory of Open Access Journals (Sweden)

    Luigi Colombo

    2013-08-01

    Full Text Available La difesa delle città da eventi naturali, come i terremoti, richiede sia il miglioramento delle qualità costruttive degli edifici, sia la riduzione consistente della loro danneggiabilità. Questi requisiti sono conseguibili, per gli edifici di nuova costruzione, attraverso l’applicazione della normativa anti-simica, e, per quelli esistenti, utilizzando strumenti che si basano su un’attenta classificazione della predisposizione al danneggiamento (vulnerabilità, sia per l’aspetto costruttivo sia per quello strutturale, materico e geo-ambientale.The Italian land has a great amount of both ancient outstanding buildings and modern ones. Nowadays, risk evaluation and analysis are extremely useful to prevent the dangerous natural calamities, which have always been happening in Italy, involving both human lives and structures maintenance. This is a very complex problem which requires a wide knowledge concerning structural, material and territorial information: a GIS system could be the effective instrument able to automatize analysis processes, to provide thematic outputs and to help the users in operational choices and online analyses. The paper deals with a GIS application in the little town of Verdellino, close to Bergamo, which has been developed carrying out a detailed geo-database for seismic buildings classification. The experience has proved the meaningful role of informatics instruments in visualization, risk classification and in pre/ post events management for a more general safeguard.

  19. Perceptions of per diems in the health sector: evidence and implications

    OpenAIRE

    Vian, Taryn; Miller, Candace; Themba, Zione; Bukuluki, Paul

    2012-01-01

    Per diems are used to pay work-related expenses and motivate employees, yet they also can distort incentives and may be abused. This study was designed to explore perceptions of per diems among 41 high-, mid- and low-level government officers and non-governmental organization (NGO) officials in Malawi and Uganda. Interviews explored attitudes about per diems, benefits and problems for organizations and individuals, and risks and patterns of abuse. The study found that per diems provide benefi...

  20. Bankruptcy and the Per Capita Nucleolus

    NARCIS (Netherlands)

    Huijink, S.; Borm, P.E.M.; Reijnierse, J.H.; Kleppe, J.

    2013-01-01

    Abstract: This article characterizes the per capita nucleolus for bankruptcy games as a bankruptcy rule. This rule, called the cligths rule, is based on the wellknown constrained equal awards principle. The essential feature of the rule however is that, for each bankruptcy problem, it takes into

  1. Plant extracts on Hypothenemus hampei (Coleoptera: Curculionidae and Beauveria bassianaExtratos vegetais sobre Hypothenemus hampei (Coleoptera: Curculionidae e Beauveria bassiana

    Directory of Open Access Journals (Sweden)

    Janaina Zorzetti

    2012-12-01

    Full Text Available Looking for alternatives to pesticides for Hypothenemus hampei control, the objective of this study was to evaluate the potential of aqueous and ethanolic plant extracts of Moringa oleifera (Moringa and Tephrosia purpurea (tephrosia (seeds, leaves and roots and Melia azedarach (cinnamon, Nerium oleander (oleander and Azadirachta indica (neem (leaves only, on mortality and repellency of H. hampei and its compatibility with Beauveria bassiana, an important natural enemy of this pest. To assess the mortality, coffee leaves (Coffea arabica L were treated by immersion in a solution of endosulfan and plant extracts at a concentration of 10% and then offered to adults of H. hampei. The repellency was evaluated in multiple-choice tests and in no-choice tests among coffee fruit treated and untreated The compatibility between extracts and Beauveria bassiana (CG 452 was analyzed by quantifying germination, colony forming units, growth and yield / productivity of conidia. The highest mortalities were observed when leaves were treated with ethanolic extract of T. purpurea (leaves which did not differ from endosulfan, and aqueous and ethanolic extracts from M. oleifera seeds . In free-choice tests, all the ethanolic extracts showed repellent action, being higher for M. oleifera (root and T. purpurea (seed. The aqueous extracts of M. oleifera (leaves and seeds and N. oleander (leaves showed the highest repellency. In no-choice tests the highest repellency level was for coffee fruits treated with A. indica (leaves. The ethanolic extract of M. oleifera leaves negatively affected B. bassiana germination. These studies showed the potential of these plant extracts for use in the field as an alternative to chemical control, once they are also selective for B. bassiana. Visando alternativas ao uso de agrotóxicos no controle de Hypothenemus hampei, o objetivo deste trabalho foi avaliar o potencial de extratos vegetais aquosos e etanólicos de Moringa oleifera

  2. I diritti delle donne: strumenti per l’uso

    Directory of Open Access Journals (Sweden)

    Caterina Arcidiacono

    2013-01-01

    Full Text Available Abbiamo ritenuto utile riportare documenti, leggi, regolamenti e dispositivi che agiscono per il riconoscimento e l’affermazione dei diritti delle donne fornendo alcuni link che permettono l’accesso alla documentazione originale accompagnati da un breve commento descrittivo. Il rapporto sull’ineguaglianza tra uomini e donne (Gender Gap Index, la Convenzione sull’eliminazione di ogni forma di discriminazione verso le donne (CEDAW, il Rapporto della Commissione Europea sull’eguaglianza tra uomini e donne e alcuni documenti di monitoraggio delle politiche istituzionali redatti da organismi di base quali l’Afem, la Euromedcivil platform e la REMDH sono pilastri per comprendere le politiche del tempo presente.Abbiamo poi voluto effettuare una breve sintesi di documenti e trattati che fondano la posizione delle donne nella società europea contemporanea. Infine, abbiamo ritenuto utile descrivere le istituzioni italiane per la parità introducendo funzioni e compiti della figura della Consigliera di parità e del lavoro che svolge.

  3. Resource Unavailability (RU) Per Domain Behavior

    NARCIS (Netherlands)

    Karagiannis, Georgios; Westberg, L.; Bader, A.; Tschofenig, Hannes; Tschofenig, H.

    2006-01-01

    This draft specifies a Per Domain Behavior that provides the ability to Diffserv nodes located outside Diffserv domain(s), e.g., receiver or other Diffserv enabled router to detect when the resources provided by the Diffserv domain(s) are not available. The unavailability of resources in the domain

  4. Vaccinatietoestand Nederland per 1 januari 2004

    NARCIS (Netherlands)

    Abbink F; Oomen PJ; Zwakhals SLN; de Melker HE; Ambler-Huiskes A; CIE

    2005-01-01

    In dit rapport treft u de cijfers aan van de vaccinatietoestand in Nederland per 1 januari 2004 voor zuigelingen, kleuters (4-jarigen) en schoolkinderen (9-jarigen) van de cohorten 2001, 1998 en 1993.De vaccinatiegraad in Nederland is al jaren zeer goed te noemen. Het afgelopen verslagjaar is de

  5. [Status and trend for sodium content of Chinese per-packaged foods].

    Science.gov (United States)

    Zhang, Xuesong; Wang, Zhu; He, Mei; Men, Jianhua; Yang, Jingming; Shen, Xiang; Lu, Ying; Yang, Yuexin

    2014-03-01

    To collect the data on the sodium content of Chinese per-packaged foods, and to analyze the variation trend of sodium content. 1279 data on the sodium content of per-packaged foods in all were recorded and analyzed through the investigation of per-packaged food nutrition labels, and were categorized into 31 varieties. Median sodium content and variation were calculated for each variety and compared with 2004 sodium content data on China Food Composition. There are 6 per-packaged foods varieties has the median sodium content more than 500 mg/100 g. The food varieties with the highest mean sodium content were ready-to-eat food(2500 mg/100 g), followed by instant noodles (1900 mg/100 g). Compared with 1991 -2004 per-packaged foods sodium content, 13 varieties had medium sodium content that increased, and 5 varieties increased significantly, such as cake, liquid milk, instant noodles etc. The survey show that sodium content of some per-packaged food increased.

  6. Favourability towards electric utilities jumps 10 per cent in 1997

    International Nuclear Information System (INIS)

    Anon.

    1997-01-01

    A recent survey of public opinion has shown that 85 per cent of the public view their electric utility company favourably. This represents a 10 per cent increase over last year. A survey of 4,090 Canadians was conducted which looked at the perceptions of the value of electricity services compared to telephone, natural gas, banking, and home insurance services. The study showed that Canadian electric utility companies are viewed as positively as the telephone companies and almost as favourably as the banks. Some 71 per cent of respondents reported that the value they receive from their electric utility is excellent or good. Lower prices, better customer services and increased research into alternative power sources were among the benefits that Canadians perceive would result from a more competitive electricity sector. Some misgivings about deregulation included a belief that there would be less attention to environmental concerns and more outages. Four per cent of the respondents said they would 'definitely' switch to an alternative supplier of electricity, while 25 per cent said they would 'probably' switch to an alternative supplier of electricity. 2 tabs

  7. In vivo imaging of hydrogen peroxide with HyPer probes.

    Science.gov (United States)

    Bilan, Dmitry; Belousov, Vsevolod

    2018-03-22

    Hydrogen peroxide (H2O2) is a key signaling molecule involved in the regulation of both physiological and pathological cellular processes. Genetically encoded HyPer probes are currently among the most effective approaches for monitoring H2O2 dynamics in various biological systems because they can be easily targeted to specific cells and organelles. Since its development in 2006, HyPer has proved to be a robust and powerful tool in redox biology research. Recent Advances: HyPer probes were used in a variety of models to study the role of H2O2 in various redox process. HyPer has been increasingly used in the last few years for in vivo studies, which has already led to many important discoveries, for example, that H2O2 plays a key role in the regulation of signaling cascades involved in development and aging, inflammation, regeneration, photosynthetic signaling, and other biological processes. In this review, we focus on the main achievements in the field of redox biology that have been obtained from in vivo experiments using HyPer probes. Further in vivo studies of the role of H2O2 largely depend on the development of more suitable versions of HyPer for in vivo models: those having brighter fluorescence and a more stable signal in response to physiological changes in pH.

  8. Potential of soil liquefaction at Perlis, northern region of Malalysia

    Science.gov (United States)

    Ghazaly, Zuhayr Md; Rahim, Mustaqqim Abdul; Nasir, Mohamad Amzar Bin Mhd; Isa, Nur Fitriah; Zaki, Mohd Faiz Mohammad; Hassan, Zulkarnain Bin; Ismail, Zul-Atfi Bin

    2017-09-01

    Soil liquefaction is earthquake's secondary effect which could cause fatal damages and structures instability. Despite Malaysia been located in stable zone of Pacific Ring of Fire, few significant surrounded quakes like Sumatra-Andaman earthquake had prompted Malaysian's public concern, especially in Perlis area, on local seismic resistant. Hence, this research presents the analysis result of liquefaction potential of the soils, as the secondary effect of earthquake, within Perlis, northern region of Malaysia; the next strong and sustainable metropolis by using semi-empirical procedures introduced by Seed and Idriss. The study consists of two stages which were determination of the local geological and geotechnical site conditions within Perlis and analysis of soil liquefaction susceptibility by using various methods and liquefaction potential by using Simplified Procedure developed by Seed and Idriss on stress approach. There were consist of four phases implemented in order to achieve the objectives targeted for the study after problem being identified. Firstly, a comprehensive review of literature on liquefaction at Perlis was carried out. Second phase was data collection process that includes collection of Site Investigation (SI) report. Thirdly, data analysis was carried out by utilizing suitable method. The final phase was to draw conclusion and recommendation for this study. It can be concluded that the overall Perlis due to earthquake moment magnitude below 7.5 has no potential to soil liquefaction. However, with the range of liquefaction potential of 1.60 to 5.64 in Kuala Perlis area, it is liquefiable. The development of liquefaction severity map of Perlis, Malaysia in this research, may be used by others as a reference for seismic design and standard safety measures as well as for further research work.

  9. DETERMINANTS OF RESIDENTIAL PER CAPITA WATER ...

    African Journals Online (AJOL)

    This report presents the findings of the study on the determinants of residential per capita water demand of Makurdi metropolis in Benue State, Nigeria. Data for the study was obtained by the use of questionnaires, oral interviews and observations. The data was analyzed using SPSS. Twenty variables were considered in ...

  10. Tipificación Molecular del Vibrio cholerae O1 en el Perú

    Directory of Open Access Journals (Sweden)

    Huguet T José

    2000-01-01

    Full Text Available Este estudio de ribotipificación en 75 cepas de Vibrio cholerae O1 permitió identificar tres variantes ribotípicas, referidas como Per1, Per2 y Per3, aisladas durante el periodo 1991- 1999 en el Perú. La variante Per1 fue reportada tanto en la etapa epidémica y endémica del cólera, mientras que Per2 y Per3 se relacionaron sólo con la etapa endémica. Los resultados mostraron además una aparición constante y mayoritaria de la variante Per1, poniendo en evidencia la emergencia de un mismo grupo clonal en los brotes epidémicos del Perú. Las variantes ribotípicas encontradas fueron comparadas con los ribotipos de diferentes cepas referenciales de V. cholerae previamente caracterizadas. Se observó una identidad total del ribotipo Per1 con la variante ribotípica de aislamientos Asiáticos (Tailandia, encontrándose además altos índices de similitud entre los ribotipos Per1, Per2 y Per3, y evidenciándose una estrecha relación entre las cepas peruanas y los aislamientos asiáticos.

  11. Preparation and Identification of Per a 5 as a Novel American Cockroach Allergen

    Directory of Open Access Journals (Sweden)

    Ji-Fu Wei

    2014-01-01

    Full Text Available Glutathione S-transferase (GST from various arthropods can elicit allergic reactions. In the present study, Per a 5, a GST, was cloned from American cockroach (CR and expressed in both baculovirus-infected insect cell (iPer a 5 and E. coli expression (bPer a 5 systems. The secondary structures were predicted to be 45.93 and 8.69% of α-helix β-sheets in iPer a 5 and 42.54 and 8.49% of α-helix and β-sheets in bPer a 5, respectively. It is found that 4 out of 16 (25% sera from American CR allergy patients reacted to both bPer a 9 and iPer a 9 as assessed by ELISA and Western blotting analysis, confirming that Per a 5 is not a major allergen of American CR. Induction of upregulated expression of CD63 and CCR3 on passively sensitized human basophils (sera from American CR allergy patients by approximately up to 4.5- and 3.2-fold indicates that iPer a 5 and bPer a 5 are functionally active. Recombinant Per a 5 (rPer a 5 should be a useful tool for studying and understanding the role of Per a 5 in CR allergy.

  12. Ten per cent more grain

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1967-08-15

    At a low estimate, ten per cent of stored grain is lost every year to insect pests. In this article, based on a lecture given earlier this year in Switzerland, Dr. Harry E. Goresline, Food Radiation Specialist of the Food and Agriculture Organisation, now assisting the Joint FAO/IAEA Division of Atomic Energy in Food and Agriculture, explains how use of radiation can help to prevent losses and the research which has taken place to ensure its safety

  13. Twenty Questions for PER: How Does It All Fit Together?

    Science.gov (United States)

    Redish, Edward F.; Wittmann, Michael C.

    2005-09-01

    In physics education research (PER), we have focused our attention for many years on finding ways to improve our instruction and have achieved some notable successes. In this paper, we suggest that the time has come to embed this activity in a more complete and scientific view of PER, one that builds a coherent understanding of the system of teaching and learning in addition to improving the practice of our instruction. We outline five broad topics of interest for PER and discuss questions that need to be addressed in each topic over the next few years. The topics are: the model of the participants, the model of the contexts, the model of the content, the engineering of instruction, and the overall epistemology of PER — How do we decide when we think we know something?

  14. Modeling Per Capita State Health Expenditure Variat...

    Data.gov (United States)

    U.S. Department of Health & Human Services — Modeling Per Capita State Health Expenditure Variation State-Level Characteristics Matter, published in Volume 3, Issue 4, of the Medicare and Medicaid Research...

  15. Studio di Architetture e Protocolli per Reti Ottiche

    CERN Document Server

    Cucchi, R; Raffaelli, C; Vistoli, C

    1999-01-01

    Le reti ottiche basate sulla tecnologia WDM (Wavelength Division Multiplexing) sono molto promettenti per rispondere non solo alle esigenze di capacit trasmissiva ma anche per la realizzazione di reti costituite da apparati $9 esclusivamente ottici dove la lunghezza d¹onda rappresenta il circuito di comunicazione fra nodo sorgente e nodo destinatario.Questo documento prende in esame il ³trigger di II livello dell¹esperimento ATLAS come case study², ne $9 analizza le esigenze di trasmissione dei dati e descrive uno studio di fattibilit basato su una rete ottica a stella.

  16. Per-rectal portal scintigraphy in chronic liver diseases

    International Nuclear Information System (INIS)

    Frusciante, V.; Barbano, F.; Btuno, M.; Facciorusso, D.; Tonti, P.; Giacobbe, A.; Andriulli, A.; Vettori, P.G.P.

    1993-01-01

    Portal circulation has been evaluated by per-rectal portal scintigraphy in 21 controls and in 30 pts affected by chronic liver diseases. Tc99m-pertechnetate (10 mci) was given through a Nelaton's catheter in the upper rectum; a per-rectal portal shunt index (SI) was calculated. A relevant overlap is evident between controls and CHP pts; no overlap exists between controls and B or C graded cirrhosis. We conclude that the technique may be suggested to monitor the course of chronic liver diseases and different therapeutic regimens. (orig.) [de

  17. Danmarks produktivitet, værdiskabelse og nationalindkomst per arbejdstime

    DEFF Research Database (Denmark)

    Whitta-Jacobsen, Hans Jørgen; Sørensen, Peter Birch; Jørgensen, Kristian Binderup

    mængdemæssig timeproduktivitet, real værdiskabelse per arbejdstime og nationalindkomst per arbejdstime. Det gælder fx, når vi sammenligner med lande som USA, Tyskland, Frankrig og Sverige. Der er dog en bemærkelsesværdig og vedholdende tendens til, at Holland og Belgien ligger på et højere niveau end de øvrige...

  18. Una imatge val per mil paraules

    Directory of Open Access Journals (Sweden)

    Jaume Cabré

    1999-11-01

    Full Text Available Una vegada hi havia un videoclub ple de pel·lícules i a l'entrada hi havia un rètol lluminós molt bonic que deia el lema d'aquesta casa, que és una imatge val per mil paraules. I vet aquí un dia que la clientela ja se n'havia anat, però encara no havien tancat els llums, van entrar al videoclub dues rates, l'Amàlia i l'Amèlia. I van dir: "Què fem avui?" Aleshores l'Amèlia se'n va anar de seguida cap al racó de la sèrie B i va agafar una pel·lícula poc coneguda, mentre que l'Amàlia va agafar Mort a Venècia. Llavors la va començar a rosegar i l'Amèlia li va dir: "Què, què te'n sembla?", i l'Amàlia li va contestar: "Mmm... Em va agradar més la novel·la."

  19. LA LINGUA PER STUDIARE: UNA RASSEGNA BIBLIOGRAFICA

    Directory of Open Access Journals (Sweden)

    Marina Tassara

    2011-02-01

    Full Text Available I libri di testo adottati nelle scuole contengono parole sconosciute e costruzioni sintattiche e testuali complesse che rappresentano dei veri e propri “muri linguistici” per gli alunni stranieri che non possiedono una buona conoscenza della lingua italiana. Ciò facilmente determina un divario di competenze tra l’apprendente straniero e i suoi compagni e ritardi scolastici molto spesso incolmabili con conseguente perdita di motivazione e di autostima, senso di frustrazione e isolamento che a volte sfocia in un disagio psico-sociale. Tra gli strumenti adottati dalla scuola italiana per far fronte a questo problema vi sono i testi disciplinari ad alta comprensibilità che, pur mantenendo la maggior parte delle informazioni, le veicolano in una forma più semplice dal punto di vista linguistico. L’articolo fornisce una bibliografia di manuali ad alta comprensibilità il più possibile aggiornata suddivisa per ordine e grado di scuola e per materia scolastica, con l’intento di fornire agli insegnanti un aiuto nella scelta e nel reperimento dei testi.     Language for study:  a bibliography   Textbooks used in schools contain unknown words and complex sentence constructions that create real “linguistic barriers” for foreign students who do not know Italian well.  This creates an abyss between the competence of the foreign learner and his or her classmates and unsuccessful school performance which is often not made up for and leads to a loss of self-esteem, frustration, isolation, and ultimately to psycho-social malaise.  Among the tools utilized in the Italian school system to address this problem are highly comprehensible textbooks which, while containing most of the information, express the content in simpler language.  This article offers an up-dated bibliography of textbooks which are easily understandable, divided according to order and grade of school, for teachers to use in choosing the textbooks for their classes.

  20. Per Nørgårds “nordiske" periode

    DEFF Research Database (Denmark)

    Nielsen, Rie B.; Bonde, Anders

    1997-01-01

    s. 491-653 + bilag  Per Nørgård (f. 1932) er en af de nulevende danske komponister, hvis musik har givet anledning til flest skriverier. Det være sig i bøger, aviser, tidsskrifter m.m. Samtidigt foreligger fra komponisten selv et væld af artikler og manuskripter, omhandlende musikteori, analyser......, kulturkritik m.m. I en lang række af disse skrifter fra især 1980'erne og 1990'erne dukker ordet "interferens" til stadighed op i såvel Per Nørgårds egne som andres udtalelser og kommentarer, knyttet til hans kompositoriske virke. Interferensfænomenet har med tiden vist sig at have en helt central placering i...... forbindelse med hans musik, dog uden at der på noget tidspunkt er opstillet fyldestgørende definitioner af begrebet. Samtidig har Per Nørgård flere gange fremhævet, hvorledes interferensen synes at stå som en overordnet fællesnævner for hele hans produktion trods store stilistiske forskelle. Som følge deraf...

  1. Gentianaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Susy Castillo

    2013-10-01

    Full Text Available La familia Gentianaceae es reconocida en el Perú por presentar alrededor de 15 géneros y aproximadamente de 170 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004; S. Castillo, com.pers., mayormente hierbas y arbustos. En este trabajo se reconoce 103 especies endémicas en siete géneros. Los géneros con mayor número de especies endemicas son Gentianella y Macrocarpaea. Las especies endémicas ocupan principalmente las regiones de la Puna Húmeda y Seca, Páramo y Bosque Muy Húmedo Montano, entre los 1000 y 5100 m de altitud. Se aplicaron las categorías y criterios de la UICN a 99 especies. Treinta y tres especies endémicas se encuentran representadas dentro de un área protegida.

  2. Alcohol-Attributable Fraction in Liver Disease: Does GDP Per Capita Matter?

    Science.gov (United States)

    Kröner, Paul T; Mankal, Pavan Kumar; Dalapathi, Vijay; Shroff, Kavin; Abed, Jean; Kotler, Donald P

    2015-01-01

    The alcohol-attributable fraction (AAF) quantifies alcohol's disease burden. Alcoholic liver disease (ALD) is influenced by alcohol consumption per capita, duration, gender, ethnicity, and other comorbidities. In this study, we investigated the association between AAF/alcohol-related liver mortality and alcohol consumption per capita, while stratifying to per-capita gross domestic product (GDP). Data obtained from the World Health Organization and World Bank for both genders on AAF on liver disease, per-capita alcohol consumption (L/y), and per-capita GDP (USD/y) were used to conduct a cross-sectional study. Countries were classified as "high-income" and "very low income" if their respective per-capita GDP was greater than $30,000 or less than $1,000. Differences in total alcohol consumption per capita and AAF were calculated using a 2-sample t test. Scatterplots were generated to supplement the Pearson correlation coefficients, and F test was conducted to assess for differences in variance of ALD between high-income and very low income countries. Twenty-six and 27 countries met the criteria for high-income and very low income countries, respectively. Alcohol consumption per capita was higher in high-income countries. AAF and alcohol consumption per capita for both genders in high-income and very low income countries had a positive correlation. The F test yielded an F value of 1.44 with P = .357. No statistically significant correlation was found among alcohol types and AAF. Significantly higher mortality from ALD was found in very low income countries relative to high-income countries. Previous studies had noted a decreased AAF in low-income countries as compared to higher-income countries. However, the non-statistically significant difference between AAF variances of low-income and high-income countries was found by this study. A possible explanation is that both high-income and low-income populations will consume sufficient amount of alcohol, irrespective of its

  3. Blockchain per l'educació

    OpenAIRE

    Arcas Sanz, Joan Manel

    2017-01-01

    La tecnologia Blockchain o de cadena de blocs va sorgir com a suport de la xarxa de monedes virtuals Bitcoin, però amb la recent aparició dels Smart Contracts existeix la possibilitat de crear infinitud d'aplicacions que funcionin de manera distribuïda i sense la necessitat d'entitats intermediàries. En aquest article es presenta una introducció a la tecnologia Blockchain, des dels seus inicis amb Bitcoin fins a l'actualitat amb la utilització dels Smart Contracts. Posteriorment es comparen a...

  4. Tecniche integrate di rilievo per la comprensione di contesti archeologici e paesaggistici: note metodologiche per un approccio multi-scalare.

    Directory of Open Access Journals (Sweden)

    Mariangela Liuzzo

    2017-12-01

    Full Text Available L’obiettivo della ricerca consiste nello sviluppo di un metodo efficiente volto a superare la dicotomia esistente tra la documentazione di dettaglio e quella a scala più ampia, territoriale e paesaggistica, in maniera tale da innescare nuove riflessioni sugli ambiti archeologici indagati e contestualizzarli nella storia e negli spazi geografici differenziati per periodi che arrivino fino ai giorni nostri.Il poter misurare ed assorbire diversi universi contestuali (dal singolo muro all’architettura, fino al sito e al suo territorio, mettendoli a sistema e facendoli interagire nello spazio e nel tempo, è forse il contributo più importante che un lavoro di squadra multidisciplinare può offrire per la comprensione dello spazio in cui viviamo.Si presentano i risultati di due recenti attività svolte sul campo ancora in atto.

  5. Bounds on Minimum Energy per Bit for Optical Wireless Relay Channels

    Directory of Open Access Journals (Sweden)

    A. D. Raza

    2014-09-01

    Full Text Available An optical wireless relay channel (OWRC is the classical three node network consisting of source, re- lay and destination nodes with optical wireless connectivity. The channel law is assumed Gaussian. This paper studies the bounds on minimum energy per bit required for reliable communication over an OWRC. It is shown that capacity of an OWRC is concave and energy per bit is monotonically increasing in square of the peak optical signal power, and consequently the minimum energy per bit is inversely pro- portional to the square root of asymptotic capacity at low signal to noise ratio. This has been used to develop upper and lower bound on energy per bit as a function of peak signal power, mean to peak power ratio, and variance of channel noise. The upper and lower bounds on minimum energy per bit derived in this paper correspond respectively to the decode and forward lower bound and the min-max cut upper bound on OWRC capacity

  6. Short, frequent, 5-days-per-week, in-center hemodialysis versus 3-days-per week treatment: a randomized crossover pilot trial through the Midwest Pediatric Nephrology Consortium.

    Science.gov (United States)

    Laskin, Benjamin L; Huang, Guixia; King, Eileen; Geary, Denis F; Licht, Christoph; Metlay, Joshua P; Furth, Susan L; Kimball, Tom; Mitsnefes, Mark

    2017-08-01

    No controlled trials in children with end-stage kidney disease have assessed the benefits of more frequently administered hemodialysis (HD). We conducted a multicenter, crossover pilot trial to determine if short, more frequent (5 days per week) in-center HD was feasible and associated with improvements in blood pressure compared with three conventional HD treatments per week. Because adult studies have not controlled for the weekly duration of dialysis, we fixed the total treatment time at 12 h a week of dialysis during two 3-month study periods; only frequency varied from 5 to 3 days per week between study periods. Eight children (median age 16.7 years) consented at three children's hospitals. The prespecified primary composite outcome was a sustained 10% decrease in systolic blood pressure and/or a decrease in antihypertensive medications relative to each study period's baseline. Among the six patients completing both study periods, five (83.3%) experienced the primary outcome during HD performed 5 days per week but not 3 days per week; one of the six (16.7%) achieved that outcome during 3-day but not 5-day (p = 0.22) per week HD. During 5-day HD, all patients had significantly more treatments during which their pre-HD systolic (p = 0.01) or diastolic (p = 0.01) blood pressure was 10% lower than baseline. We observed that more frequent HD sessions per week was feasible and associated with improved blood pressure control, but barriers to changing thrice-weekly standard of care include financial reimbursement and the time demands associated with more frequent treatments.

  7. Estimating the Per-Base-Pair Mutation Rate in the Yeast Saccharomyces cerevisiae

    OpenAIRE

    Lang, Gregory I.; Murray, Andrew W.

    2008-01-01

    Although mutation rates are a key determinant of the rate of evolution they are difficult to measure precisely and global mutations rates (mutations per genome per generation) are often extrapolated from the per-base-pair mutation rate assuming that mutation rate is uniform across the genome. Using budding yeast, we describe an improved method for the accurate calculation of mutation rates based on the fluctuation assay. Our analysis suggests that the per-base-pair mutation rates at two genes...

  8. Leaf mass per area is independent of vein length per area: avoiding pitfalls when modelling phenotypic integration (reply to Blonder et al. 2014).

    Science.gov (United States)

    Sack, Lawren; Scoffoni, Christine; John, Grace P; Poorter, Hendrik; Mason, Chase M; Mendez-Alonzo, Rodrigo; Donovan, Lisa A

    2014-10-01

    It has been recently proposed that leaf vein length per area (VLA) is the major determinant of leaf mass per area ( MA), and would thereby determine other traits of the leaf economic spectrum (LES), such as photosynthetic rate per mass (A(mass)), nitrogen concentration per mass (N(mass)) and leaf lifespan (LL). In a previous paper we argued that this 'vein origin' hypothesis was supported only by a mathematical model with predestined outcomes, and that we found no support for the 'vein origin' hypothesis in our analyses of compiled data. In contrast to the 'vein origin' hypothesis, empirical evidence indicated that VLA and LMA are independent mechanistically, and VLA (among other vein traits) contributes to a higher photosynthetic rate per area (A(area)), which scales up to driving a higher A(mass), all independently of LMA, N(mass) and LL. In their reply to our paper, Blonder et al. (2014) raised questions about our analysis of their model, but did not address our main point, that the data did not support their hypothesis. In this paper we provide further analysis of an extended data set, which again robustly demonstrates the mechanistic independence of LMA from VLA, and thus does not support the 'vein origin' hypothesis. We also address the four specific points raised by Blonder et al. (2014) regarding our analyses. We additionally show how this debate provides critical guidance for improved modelling of LES traits and other networks of phenotypic traits that determine plant performance under contrasting environments. © The Author 2014. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  9. Parallel search engine optimisation and pay-per-click campaigns: A comparison of cost per acquisition

    Directory of Open Access Journals (Sweden)

    Wouter T. Kritzinger

    2017-07-01

    Full Text Available Background: It is imperative that commercial websites should rank highly in search engine result pages because these provide the main entry point to paying customers. There are two main methods to achieve high rankings: search engine optimisation (SEO and pay-per-click (PPC systems. Both require a financial investment – SEO mainly at the beginning, and PPC spread over time in regular amounts. If marketing budgets are applied in the wrong area, this could lead to losses and possibly financial ruin. Objectives: The objective of this research was to investigate, using three real-world case studies, the actual expenditure on and income from both SEO and PPC systems. These figures were then compared, and specifically, the cost per acquisition (CPA was used to decide which system yielded the best results. Methodology: Three diverse websites were chosen, and analytics data for all three were compared over a 3-month period. Calculations were performed to reduce the figures to single ratios, to make comparisons between them possible. Results: Some of the resultant ratios varied widely between websites. However, the CPA was shown to be on average 52.1 times lower for SEO than for PPC systems. Conclusion: It was concluded that SEO should be the marketing system of preference for e-commerce-based websites. However, there are cases where PPC would yield better results – when instant traffic is required, and when a large initial expenditure is not possible.

  10. Reassessment of NRC's dollar per person-rem conversion factor policy

    International Nuclear Information System (INIS)

    1995-12-01

    The US Nuclear Regulatory Commission (NRC) has completed a review and analysis of its dollar per person-rem conversion factor policy. As a result of this review, the NRC has decided to adopt a $2000 per person-rem conversion factor, subject it to present worth considerations, and limit its scope solely to health effects. This is in contrast to the previous policy and staff practice of using an undiscounted $1000 per person-rem conversion factor that served as a surrogate for all offsite consequences (health and offsite property). The policy shift has been incorporated in ''Regulatory Analysis Guidelines of the US Nuclear Regulatory Commission,'' NUREG/BR-0058, Revision 2, November 1995

  11. Perceptions of per diems in the health sector: evidence and implications.

    Science.gov (United States)

    Vian, Taryn; Miller, Candace; Themba, Zione; Bukuluki, Paul

    2013-05-01

    Per diems are used to pay work-related expenses and motivate employees, yet they also can distort incentives and may be abused. This study was designed to explore perceptions of per diems among 41 high-, mid- and low-level government officers and non-governmental organization (NGO) officials in Malawi and Uganda. Interviews explored attitudes about per diems, benefits and problems for organizations and individuals, and risks and patterns of abuse. The study found that per diems provide benefits such as encouraging training, increasing staff motivation and supplementing salary. Despite these advantages, respondents voiced many discontents about per diems, stating that they create conflict, contribute to a negative organizational culture where people expect to be paid for all activities, and lead to negative changes in work time allocation. Work practices are also manipulated in order to maximize financial gain by slowing work, scheduling unnecessary trainings, or exaggerating time needed for tasks. Officials may appropriate per diems meant for others or engage in various forms of fraud for personal financial gain. Abuse seemed more common in the government sector due to low pay and weaker controls. A striking finding was the distrust that lower-level workers felt toward their superiors: allowances were perceived to provide unfair financial advantages to already better-off and well-connected staff. To curb abuse of per diems, initiatives must reduce pressures and incentives to abuse, while controlling discretion and increasing transparency in policy implementation. Donors can play a role in reform by supporting development of policy analysis tools, design of control mechanisms and evaluation of reform strategies.

  12. Study of electroless nickel plating on PerFactoryTM rapid prototype model

    OpenAIRE

    J.C. Rajaguru; C. Au, M. Duke

    2012-01-01

    This paper presents an investigation of electroless nickel plating on PerFactoryTM rapid prototype model built on PerFactoryTM R05 material. PerFactoryTM R05 is acrylic based photo sensitive resin. It is a popular material in rapid prototyping using PerFactoryTM method which employs addictive manufacturing technique to build prototypes for visual inspection, assembly etc. Metallization of such a prototype can extend the application envelop of the rapid prototyping technique as they can be use...

  13. Using ichthyotoxic plants as bioinsecticide: A literature review

    Directory of Open Access Journals (Sweden)

    J. N. ANDRADE

    2015-12-01

    Full Text Available ABSTRACTSome ichthyotoxic plants are study object aiming to discover promising substances in the field of Biotechnology, in search of plant extracts which can be used or even transformed into natural insecticides. This paper presents a bibliographical survey in order to check the traditional use of ichthyotoxic plants as bioinsecticide. Among the plants identified as ichthyotoxic, the most cited in traditional use are those from the genera Derris, Serjania, Lonchocarpus, Magonia, and Tephrosia. The survey suggests that ichthyotoxic plant extracts can contain classes of chemical compounds such as isoflavonoids and tannins with a bioinsecticidal effect and, thus, they can be used in Biotechnology, contributing to reduce the use of synthetic insecticides that present a high toxicity level.

  14. Zebrafish Lacking Circadian Gene per2 Exhibit Visual Function Deficiency

    Directory of Open Access Journals (Sweden)

    Deng-feng Huang

    2018-03-01

    Full Text Available The retina has an intrinsic circadian clock, but the importance of this clock for vision is unknown. Zebrafish offer many advantages for studying vertebrate vision and circadian rhythm. Here, we explored the role of zebrafish per2, a light-regulated gene, in visual behavior and the underlying mechanisms. We observed that per2 mutant zebrafish larvae showed decreased contrast sensitivity and visual acuity using optokinetic response (OKR assays. Using a visual motor response (VMR assay, we observed normal OFF responses but abnormal ON responses in mutant zebrafish larvae. Immunofluorescence showed that mutants had a normal morphology of cone photoreceptor cells and retinal organization. However, electron microscopy showed that per2 mutants displayed abnormal and decreased photoreceptor ribbon synapses with arciform density, which resulted in retinal ON pathway defect. We also examined the expression of three cone opsins by quantitative real-time PCR (qRT-PCR, and the expression of long-wave-sensitive opsin (opn1lw and short-wave-sensitive opsin (opn1sw was reduced in mutant zebrafish larvae. qRT-PCR analyses also showed a down-regulation of the clock genes cry1ba and bmal1b in the adult eye of per2 mutant zebrafish. This study identified a mechanism by which a clock gene affects visual function and defined important roles of per2 in retinal information processing.

  15. El análisis conductual en el Perú

    Directory of Open Access Journals (Sweden)

    Luís Benítez Morales

    2006-01-01

    Full Text Available describen los antecedentes y escenarios de iniciación del movimiento conductual en elPerú. Se destaca la labor de las organizaciones e instituciones académicas y profesionales cuyasactividades y planes de estudio incidieron en la formación, desarrollo y difusión de la psicología desde una perspectiva conductual en el Perú. Se mencionan los artículos aparecidos en revistasy la publicación de libros, así como los trabajos presentados en los Congresos Nacionales dePsicología relacionados con el enfoque conductual. Se dan a conocer los ámbitos y alcances dela labor profesional desarrollada por analistas conductuales en contextos clínicos y educativosprincipalmente. Finalmente se realiza una evaluación del análisis conductual desde susorígenes hasta la actualidad y se señalan sus perspectivas futuras en el Perú.

  16. The Application of SNiPER to the JUNO Simulation

    Science.gov (United States)

    Lin, Tao; Zou, Jiaheng; Li, Weidong; Deng, Ziyan; Fang, Xiao; Cao, Guofu; Huang, Xingtao; You, Zhengyun; JUNO Collaboration

    2017-10-01

    The JUNO (Jiangmen Underground Neutrino Observatory) is a multipurpose neutrino experiment which is designed to determine neutrino mass hierarchy and precisely measure oscillation parameters. As one of the important systems, the JUNO offline software is being developed using the SNiPER software. In this proceeding, we focus on the requirements of JUNO simulation and present the working solution based on the SNiPER. The JUNO simulation framework is in charge of managing event data, detector geometries and materials, physics processes, simulation truth information etc. It glues physics generator, detector simulation and electronics simulation modules together to achieve a full simulation chain. In the implementation of the framework, many attractive characteristics of the SNiPER have been used, such as dynamic loading, flexible flow control, multiple event management and Python binding. Furthermore, additional efforts have been made to make both detector and electronics simulation flexible enough to accommodate and optimize different detector designs. For the Geant4-based detector simulation, each sub-detector component is implemented as a SNiPER tool which is a dynamically loadable and configurable plugin. So it is possible to select the detector configuration at runtime. The framework provides the event loop to drive the detector simulation and interacts with the Geant4 which is implemented as a passive service. All levels of user actions are wrapped into different customizable tools, so that user functions can be easily extended by just adding new tools. The electronics simulation has been implemented by following an event driven scheme. The SNiPER task component is used to simulate data processing steps in the electronics modules. The electronics and trigger are synchronized by triggered events containing possible physics signals. The JUNO simulation software has been released and is being used by the JUNO collaboration to do detector design optimization, event

  17. The influence of dose per fraction on repair kinetics

    International Nuclear Information System (INIS)

    Rojas, A.; Joiner, M.C.

    1989-01-01

    The use of multiple fractions per day (MFD) in radiotherapy requires information about the rate of repair of radiation injury. It is important to know the minimum interval between fractions necessary for maximum sparing of normal tissue damage, whether rate of repair is dependent on the size of dose per fraction and if it is different in early and late responding tissues and in tumours. To address these questions, the rate of repair between radiation dose fractions was measured in mouse skin (acute damage), mouse kidney (late damage) and a mouse tumour (carcinoma NT). Skin and kidney measurements were made using multiple split doses of X-rays, followed by a neutron top-up. For skin, faster recovery was obtained with 4.4 Gy fractions (t1/2 = 3.46 ± 0.88 h). In contrast kidney showed slower recovery at a low dose per fraction of 2 Gy (t1/2 = 1.69 ± 0.39 h) than at a higher dose of 7 Gy per fraction (t1/2 = 0.92 ± 0.1h). These data show that repair rate is dependent on the size of dose per fraction, but not in a simple way. T1/2 values now available for many different tissues generally lie in the range of 1-2h, and are not correlated with proliferation status or early versus late response to treatment. At the doses used currently in clinical MFD treatments, these data indicate that damage in almost all normal tissues would increase if interfraction intervals less than 6 h were used. The t1/2 for CaNT (0.31 ± 0.15 h) is less than for any normal tissue. This underlines that the excess morbidity resulting from interfraction intervals < 6 h will not be paralleled by an increased effect in tumours. (author). 25 refs.; 7 figs

  18. Asclepiadaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Asclepiadaceae es reconocida en el Perú por presentar 27 géneros y 107 especies (Brako & Zarucchi, 1993, mayormente bejucos y hierbas. Esta familia se halla bajo revisión sistemática. Para la flora peruana, estos estudios en desarrollo probablemente concluyan con la necesidad de un reordenamiento de los taxones a nivel de los géneros (S. Liede, com. pers.. Dada la escasez de colecciones herborizadas y la falta de consenso sobre los taxones, aquí se reconocen provisionalmente 43 endemismos. En general, los endemismos en esta familia ocupan las regiones Mesoandina y Bosques Muy Húmedos Montanos, entre los 900 y 2600 m de altitud. Se aplicaron las categorías y criterios de la UICN a cinco especies. Dos endémicas se encuentran registradas en el Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  19. PerPos: A Platform Providing Cloud Services for Pervasive Positioning

    DEFF Research Database (Denmark)

    Blunck, Henrik; Godsk, Torben; Grønbæk, Kaj

    2010-01-01

    -based building model manager that allows users to manage building models stored in the PerPos cloud for annotation, logging, and navigation purposes. A core service in the PerPos platform is sensor fusion for positioning that makes it seamless and efficient to combine a rich set of position sensors to obtain...

  20. GDP PER CAPITA, PROTEST INTENSITY AND REGIME TYPE: A QUANTITATIVE ANALYSIS

    Directory of Open Access Journals (Sweden)

    A. V. Korotayev

    2016-01-01

    Full Text Available The study suggests that the relationship between per capita GDP and intensity of antigovernment demonstrations is not negative as tends to be believed; we are rather dealing with an inverted U-shaped relationship: the highest levels of antigovernment demonstration intensity are typical for countries with neither the lowest nor the highest values of GDP per capita, but rather with intermediate values of this indicator. Thus, for higher values of per capita GDP we observe a negative correlation between GDP per capita and the antigovernment demonstration intensity, and for lower values it is positive. This correlation is partly explained by the following points: (1 GDP growth in authoritarian regimes leads to increased pro-democracy movement, and hence to intensifi cation of the anti-government demonstrations. And since in our database (as well as in reality authoritarian states constitute a very high percentage of the number of states with the lowest values of per capita income, the effect of the growth of internal pressure on authoritarian regimes towards democracy with economic growth to some extent (but no not completely explains a strong correlation between GDP per capita and the intensity of antigovernment demonstrations for low and middle income countries. (2 In the range of per capita GDP up to $ 20000, the increase in per capita GDP is quite strongly correlated with a decrease in the proportion of authoritarian regimes and the increasing share of nonauthoritarian regimes (democratic and intermediate. The presence of non-authoritarian regimes in this range is signifi cantly positively correlated with the higher intensity of anti-government demonstrations. This is another mechanism that contributes to the presence of a strong positive correlation between GDP per capita and the intensity of anti-government demonstrations in the range of interest to us. At the same time we have done a further analysis that has

  1. CALiPER Exploratory Study: Recessed Troffer Lighting

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Naomi J.; Royer, Michael P.; Poplawski, Michael E.

    2013-04-28

    This report describes an exploration of troffer lighting as used in office and classroom spaces, which was conducted by the CALiPER program. Twenty-four pairs of 2×2 and 2×4 troffers were procured anonymously, documented, tested for photometric and electrical performance, and installed in a mockup office space in Portland, Oregon. Three of the pairs were T8 fluorescent benchmark products, 12 were dedicated LED troffers, five were fluorescent troffers modified for LED lamps (sometimes referred to as "tubes"), and another four troffers were modified with LED retrofit kits. The modifications were performed by a commercial electrical contractor, following the instructions provided by the retrofit lamp or kit manufacturer. Once installed in the mockup facility, the converted luminaires were examined by a NRTL (Nationally Recognized Testing Laboratory) safety expert, who provided feedback on safety issues. In September 2012, a group of lighting designers, engineers, and facility managers were brought in to observe the LED luminaires in comparison to fluorescent benchmarks. This report documents performance in measures that go beyond illuminance values or luminaire efficacy. Dedicated LED troffers are ready to compete with fluorescent troffers in terms of efficacy (lumens per watt), and in many lighting quality issues such as glare, light distribution, visual appearance, and color quality. That is not to say that each one is stellar, but each one tested in this CALiPER study bested the fluorescent benchmarks in terms of efficacy, and almost all were rated highly in several categories -- only one luminaire of twelve performed consistently poorly.

  2. Streblidae de murciélagos de Lima: dos citas nuevas para Perú Streblidae of bats from Lima: two new cites for Perú

    Directory of Open Access Journals (Sweden)

    Guillermo L. Claps

    2005-07-01

    Full Text Available Se presentan nuevos registros de Streblidae para el departamento Lima (Perú, que parasitan a tres especies de murciélagos de la familia Phyllostomidae: Anoura geoffroyi Gray, Carollia perspicillata (Linneo y Desmodus rotundus (Geoffroy. Se amplía la distribución geográfica de Anastrebla modestini Wenzel, Aspidoptera falcata Wenzel, Exastinion clovisi (Pessôa & Guimarães, Megistopoda aranea (Coquillett, Speiseria ambigua Kessel y Strebla wiedemanni Kolenati (Diptera, Streblidae, dado que se registran por primera vez en el departamento, y A. modestini y E. clovisi se mencionan por primera vez en Perú.New distributional records for bat ectoparasites (Streblidae, are presented for the Department of Lima (Perú. They were reported as collected on bats of the family Phyllostomidae: Anoura geoffroyi Gray, Carollia perspicillata (Linneo and Desmodus rotundus (Geoffroy. The distribution of Anastrebla modestini Wenzel, Aspidoptera falcata Wenzel, Exastinion clovisi (Pessôa & Guimarães, Megistopoda aranea (Coquillett, Speiseria ambigua Kessel and Strebla wiedemanni Kolenati (Diptera, Streblidae, is extended to the Department of Lima, and Anastrebla modestini and Exastinion clovisi are added to the fauna of Perú.

  3. Tres nuevos registros de asteroideos (Echinodermata: Asteroidea de Perú

    Directory of Open Access Journals (Sweden)

    Yuri Hooker

    2012-02-01

    Full Text Available En el presente trabajo se registran 3 nuevos asteroideos (Echinodermata: Asteroidea de aguas someras (4 - >50 m para el Perú: Astropecten regalis Gray, 1840, Paulia horrida Gray 1840 y Meyenaster gelatinosus (Meyen, 1834. Astropecten regalis se conocía desde el Golfo de California hasta Panamá, en el presente trabajo, se amplía su distribución hasta Máncora, Perú. La distribución geográfica de Paulia horrida era conocida desde Baja California, hasta Isla Cocos, Costa Rica, en este estudio se amplía su distribución geográfica hasta Punta Sal, Perú. A Meyenaster gelatinosus se le conocía solo de Chile, en el presente trabajo se registra y confirma su presencia en el Perú, ampliando su distribución norte hasta San Juan de Marcona. Se proporciona información morfológica de las especies, características del hábitat y fotografías in situ y de los especímenes recién recolectados.

  4. 78 FR 46421 - Proposed Information Collection (Per Diem for Nursing Home Care of Veterans in State Homes; Per...

    Science.gov (United States)

    2013-07-31

    ... State homes providing nursing home and adult day health services care to Veterans. VA requires... Diem for Nursing Home Care of Veterans in State Homes; Per Diem for Adult Day Care of Veterans in State... information needed to ensure that nursing home and adult day health care facilities are providing high quality...

  5. PER-1 production in a urinary isolate of Providencia rettgeri.

    Science.gov (United States)

    Bahar, G; Eraç, B; Mert, A; Gülay, Z

    2004-08-01

    A Providencia rettgeri strain resistant to extended-spectrum cephalosporins and intermediate to aztreonam was isolated from the urine of a patient hospitalized in the urology clinic of SSK Educational Hospital in Ankara. Clavulanic acid restored the activity of extended-spectrum cephalosporins, suggesting that the strain was harboring an extended-spectrum beta-lactamase. Since the PER-1 enzyme is widespread in Turkey, and had been already detected in a related species such as Proteus mirabilis, the Providencia strain was suspected of harboring a PER-1 enzyme, which was indeed detected by PCR. This is the first description in a P. rettgeri isolate of a PER-1 enzyme which is widespread among Acinetobacter baumanni and Pseudomonas aeruginosa strains in Turkey.

  6. Utilization of Tephrosia vogelii in controlling ticks in dairy cows by ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-09-01

    Sep 1, 2009 ... Available online at http://www.academicjournals.org/AJB. ISSN 1684–5315 © 2009 ... Ticks are a problem in dairy production causing signi- ... the Social Sciences. ... modern medicine by isolation of the active ingredient, rotenone, in ... livestock and game areas around Lake Mburo National Park in. Uganda ...

  7. SU-F-T-501: Dosimetric Comparison of Single Arc-Per-Beam and Two Arc-Per-Beam VMAT Optimization in the Monaco Treatment Planning System

    Energy Technology Data Exchange (ETDEWEB)

    Kalet, A; Cao, N; Meyer, J; Dempsey, C [University of Washington Medical Center, Seattle, WA (United States); Seattle Cancer Care Alliance, Seattle, WA (United States); Richardson, H [Seattle Cancer Care Alliance, Seattle, WA (United States)

    2016-06-15

    Purpose: The purpose of this study was to evaluate the dosimetric and practical effects of the Monaco treatment planning system “max arcs-per-beam” optimization parameter in pelvic radiotherapy treatments. Methods: A total of 17 previously treated patients were selected for this study with a range of pelvic disease site including prostate(9), bladder(1), uterus(3), rectum(3), and cervix(1). For each patient, two plans were generated, one using a arc-per-beam setting of ‘1’ and another with setting of ‘2’. The setting allows the optimizer to add a gantry direction change, creating multiple arc passes per beam sequence. Volumes and constraints established from the initial clinical treatments were used for planning. All constraints and dose coverage objects were kept the same between plans, and all plans were normalized to 99.7% to ensure 100% of the PTV received 95% of the prescription dose. We evaluated the PTV conformity index, homogeneity index, total monitor units, number of control points, and various dose volume histogram (DVH) points for statistical comparison (alpha=0.05). Results: We found for the 10 complex shaped target volumes (small central volumes with extending bilateral ‘arms’ to cover nodal regions) that the use of 2 arcs-per-beam achieved significantly lower average DVH values for the bladder V20 (p=0.036) and rectum V30 (p=0.001) while still meeting the high dose target constraints. DVH values for the simpler, more spherical PTVs were not found significantly different. Additionally, we found a beam delivery time reduction of approximately 25%. Conclusion: In summary, the dosimetric benefit, while moderate, was improved over a 1 arc-per-beam setting for complex PTVs, and equivalent in other cases. The overall reduced delivery time suggests that the use of multiple arcs-per-beam could lead to reduced patient on table time, increased clinical throughput, and reduced medical physics quality assurance effort.

  8. El análisis conductual en el Perú

    Directory of Open Access Journals (Sweden)

    Luis Benítez Morales

    2010-07-01

    Full Text Available Se describen los antecedentes y escenarios de iniciación del movimiento conductual en el Perú. Se destaca la labor de las organizaciones e instituciones académicas y profesionales cuyas actividades y planes de estudio incidieron en la formación, desarrollo y difusión de la psicología desde una perspectiva conductual en el Perú. Se mencionan los artículos aparecidos en revistas y la publicación de libros, así como los trabajos presentados en los Congresos Nacionales de Psicología relacionados con el enfoque conductual. Se dan a conocer los ámbitos y alcances de la labor profesional desarrollada por analistas conductuales en contextos clínicos y educativos principalmente. Finalmente se realiza una evaluación del análisis conductual desde sus orígenes hasta la actualidad y se señalan sus perspectivas futuras en el Perú

  9. CALiPER Retail Lamps Study 3

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2014-02-01

    This is a special CALiPER report on LED lamps available through the retail marketplace and targeted toward general consumers. It follows similar reports published in 2011 and 2012 (products purchased in 2010 and 2011), and is intended as a continuation that identifies long-term trends. For this report, products were selected to investigate specific hypotheses, rather than represent a sample of the increasingly large retail LED market.

  10. Seasonal abundance, distribution, and catch per unit effort using gill ...

    African Journals Online (AJOL)

    Catch per unit effort was obtained for the fish of the Sundays .... Methods. Catch per unit effort (numbers and weight/net) of fish in the estuary was obtained from 55 .... Table 1 CPUE (number and mass) of fish caught monthly using gill-net over 12·h periods with 55 nettings at .... The abundance of some other species may.

  11. 47 CFR 64.1509 - Disclosure and dissemination of pay-per-call information.

    Science.gov (United States)

    2010-10-01

    ... each such service; and (4) A statement of the pay-per-call service provider's name, business address... name and mailing address of any provider of pay-per-call services offered by that carrier; and (2... 47 Telecommunication 3 2010-10-01 2010-10-01 false Disclosure and dissemination of pay-per-call...

  12. Feasibility of a daly of no more than 10-4 per person per year for water reuse in agriculture, in developing countries

    Directory of Open Access Journals (Sweden)

    Ivanildo Hespanhol

    2009-08-01

    Full Text Available DALYs are a measure of the health of a population or burden of disease due to a specific disease or risk factor. It evaluates the time lost because of disability or death from diseases compared with a long life free of disability in the absence of disease. DALYs are calculated as the sum of years of life lost by premature mortality (YLL and years of healthy life lost in states of less than fully health, i.e., years lived with a disability (YDL, which are standardized by means of severity weights, thus: DALY=YLL+YLD. WHO has established for wastewater use in irrigation the same reference level of health protection as established for drinking water quality, i.e., the additional burden of disease from consuming water irrigated food should not exceed 10-6 DALY (Disability-Adjusted Life Years loss per person per year (pppy. Such a restrictive risk is almost impossible to be attained in most developing countries which may not be able to afford the cost of wastewater treatment and of other protective measures, even for restrict irrigation. This paper analyses which protective measures are able to be implemented in developing countries and proposes a tolerable disease burden of no more than 10-4 DALY per person per year. In order to evaluate this proposal it is mandatory to adopt a methodology of cost/benefit, through the development of epidemiologic studies and the identification of local characteristics and constraints, particularly the ones related to public health, technical, socio economical and environmental conditions.

  13. ''High intensity per bunch'' working group

    International Nuclear Information System (INIS)

    2001-01-01

    Third Generation Light Sources are supposed to store high intensity beams not only in many tightly spaced bunches (multibunch operation), but also in few bunch or even single lunch modes of operation, required for example for time structure experiments. Single bunch instabilities, driven by short-range wake fields, however spoil the beam quality, both longitudinally and transversely. Straightforward ways of handling them, by pushing up the chromaticity (ζ = ΔQ/(Δp/p)) for example, enabled to raise the charge per bunch, but to the detriment of beam lifetime. In addition, since the impedance of the vacuum chamber deteriorates with the installation of new insertion devices, the current thresholds tend to dope down continuously. The goal of this Working Group was then to review these limitations in the existing storage rings, where a large number of beam measurements have been performed to characterise them, and to discuss different strategies which are used against them. About 15 different laboratories reported on the present performance of storage rings, experiences gained in high charge per bunch, and on simulation results and theoretical studies. More than 25 presentations addressed the critical issues and stimulated the discussion. Four main topics came out: - Observation and experimental data; - Impedance studies and tracking codes; - Theoretical investigations; - Cures and feedback. (author)

  14. Fruizioni immateriali per la promozione territoriale

    Directory of Open Access Journals (Sweden)

    Mauro Francini

    2012-11-01

    Full Text Available Al fine di consentire ad un contesto territoriale di diventare competitivo è necessario che lo stesso promuova altresì la propria immagine con una presenza intelligente sul web (fruizione immateriale; l’obiettivo principale è quello di favorire la virtualizzazione del patrimonio territoriale restituendolo in rete come “bene comune” per i cittadini e per i visitatori, permettendo alle amministrazioni di internazionalizzare la conoscenza dello stesso bene e dell’intero territorio, nonché migliorando lo stato dell’arte sia in termini di ricaduta scientifica che di prodotto territoriale. Tale obiettivo di ricerca necessita l’adozione di tecniche avanzate, modelli condivisi di indicizzazione e identificazione univoca, utili a produrre anche percorsi e “mappature” tematiche in grado di rendere facilmente fruibile e di promuovere un’offerta territoriale coordinata ed intelligente, a garanzia di un facile accesso alla rete dei servizi in linea con le esigenze dei residenti e dei turisti, permettendo, contestualmente, agli stessi di interagire e di integrare direttamente le informazioni. Particolare riguardo, inoltre, deve essere riservato ai rapporti intercorrenti tra città-campagna e tra aree interne-costa, anche al fine di ottimizzare delle connessioni tra il miglioramento dei bilanci energetici e ambientali dei territori e la gestione delle risorse naturalistiche e socio-culturali, secondo principi di equità e sostenibilità.

  15. Per Bilde's Place in Research on Josephus

    NARCIS (Netherlands)

    Mason, Steven; Becker, Eve-Marie; Horning Jensen, Morten; Mortensen, Jacob

    2016-01-01

    Per Bilde of Aarhus played a pivotal role in generating the seismic shifts that created the subdiscipline of Josephus research in the 1970s through 1990s. His 1988 book Flavius Josephus between Jerusalem and Rome, which developed lines from his 1983 dissertation on Josephus as historian with respect

  16. Macroenvironmental factors including GDP per capita and physical activity in Europe.

    Science.gov (United States)

    Cameron, Adrian J; Van Stralen, Maartje M; Kunst, Anton E; Te Velde, Saskia J; Van Lenthe, Frank J; Salmon, Jo; Brug, Johannes

    2013-02-01

    Socioeconomic inequalities in physical activity at the individual level are well reported. Whether inequalities in economic development and other macroenvironmental variables between countries are also related to physical activity at the country level is comparatively unstudied. We examined the relationship between country-level data on macroenvironmental factors (gross domestic product (GDP) per capita, public sector expenditure on health, percentage living in urban areas, and cars per 1000 population) with country-level physical activity prevalence obtained from previous pan-European studies. Studies that assessed leisuretime physical activity (n = 3 studies including 27 countries in adults, n = 2 studies including 28 countries in children) and total physical activity (n = 3 studies in adults including 16 countries) were analyzed separately as were studies among adults and children. Strong and consistent positive correlations were observed between country prevalence of leisure-time physical activity and country GDP per capita in adults (average r = 0.70; all studies, P G 0.05). In multivariate analysis, country prevalence of leisure-time physical activity among adults remained associated with country GDP per capita (two of three studies) but not urbanization or educational attainment. Among school-age populations, no association was found between country GDP per capita and country prevalence of leisure-time physical activity. In those studies that assessed total physical activity (which also includes occupational and transport physical activity), no association with country GDP per capita was observed. Clear differences in national leisure-time physical activity levels throughout Europe may be a consequence of economic development. Lack of economic development of some countries in Europe may make increasing leisure-time physical activity more difficult. Further examination of the link between country GDP per capita and national physical activity levels (across

  17. Split SR-RLS for the Joint Initialization of the Per-Tone Equalizers and Per-Tone Echo Cancelers in DMT-Based Receivers

    Directory of Open Access Journals (Sweden)

    Ysebaert Geert

    2004-01-01

    Full Text Available In asymmetric digital subscriber lines (ADSL, the available bandwidth is divided in subcarriers or tones which are assigned to the upstream and/or downstream transmission direction. To allow efficient bidirectional communication over one twisted pair, echo cancellation is required to separate upstream and downstream channels. In addition, intersymbol interference and intercarrier interference have to be reduced by means of equalization. In this paper, a computationally efficient algorithm for adaptively initializing the per-tone equalizers (PTEQ and per-tone echo cancelers (PTEC is presented. For a given number of equalizer and echo canceler taps per-tone, it was shown that the joint PTEQ/PTEC receiver structure is able to maximize the signal-to-noise ratio (SNR on each subcarrier and hence also the achievable bit rate. The proposed initialization scheme is based on a modification of the square root recursive least squares (SR-RLS algorithm to reduce computational complexity and memory requirement compared to full SR-RLS, while keeping the convergence rate acceptably fast. Our performance analysis will show that the proposed method converges in the mean and an upper bound for the step size is given. Moreover, we will indicate how the presented initialization method can be reused in several other ADSL applications.

  18. Increasing number of authors per paper in Korean science and technology papers

    Directory of Open Access Journals (Sweden)

    Hyunju Jang

    2016-08-01

    Full Text Available We examined changes in the number of authors per paper for science and technology papers (agricultural sciences, engineering and technologies, medical sciences, and natural sciences in Korea. We employed the Scopus database to examine the change in the number of authors in papers, which were published from 2000 to 2015 in the 234 Korean academic journals indexed on Scopus. We found that the global trend of growth in the number of authors per paper is evident in Korea as well. While there was little evidence of a correlation with the citation per paper, a positive correlation was found between with the field-weighted citation impact, another measure of a paper’s impact, in medical and natural science papers. In terms of the type of collaboration, we found that international collaboration papers had the highest number of authors, followed by national and institutional collaborations. The number of authors per paper was highest for those published in the top 10% journals by Source Normalized Impact per Paper, followed by Scopus-indexed journals, while papers published in Korea Citation Index had the lowest number of authors per paper. We propose that the rise in the number of authors per paper in Korean papers may be ascribed to many Korean research programs encouraging group research and the widespread availability of the internet, which has stimulated joint research efforts and encouraged international collaboration.

  19. Sintering of beryllium oxide with 3-4 per cent elemental boron

    International Nuclear Information System (INIS)

    Pointud, R.; Rispal, Ch.; Le Garec, M.

    1958-01-01

    In order to manufacture a baffle absorbing neutrons of various energies, there was developed or mixture of a slower and an absorber. It is made by hot pressing impure beryllium containing boron carbide. The dense briquette has 100 x 100 x 50 mm and is machined on all her faces. She is of 2,85 density and about 3 to 4 per cent porosity, according to 5 per cent of boron. Difference of boron amount is lower than ten per cent between any two points of the briquette. (author) [fr

  20. Adjetivos modificados con per- y prae- en Tácito

    Directory of Open Access Journals (Sweden)

    Joaquín Villalba Álvarez

    1998-06-01

    Full Text Available Throughout Latinity it is a common opinion the intensive force of some preverbs like per- or prae-, when they form modified adjectives (seuerus-perseuerus. This paper tries to analyse such type of adjectives in the works of Tacitus. After explaining the origin of these formations (seemingly proceeding from the sermo plebeius, and their different phases of creation in Latin literature, we review aH the forms found in Tacitus (eight with per- and seventeen with prae-, in order to examine their superlative force, their uis intentiua.

  1. Convergence in energy consumption per capita among ASEAN countries

    International Nuclear Information System (INIS)

    Mishra, Vinod; Smyth, Russell

    2014-01-01

    We test for convergence in energy consumption per capita among ASEAN countries over the period 1971 to 2011 using the panel KPSS stationarity test and panel Lagrange multiplier (LM) unit root test. The results for the panel stationarity and unit root tests with structural breaks find support for energy convergence in ASEAN. - Highlights: • We test for convergence in energy consumption per capita among the ASEAN nations. • Univariate conventional unit root tests provide mixed evidence of convergence. • Panel unit root tests with structural breaks support convergence hypothesis

  2. Alternative Estimates of Personal Income Per Capita in Russian Regions

    Directory of Open Access Journals (Sweden)

    Andrey Viktorovich Yantsen

    2017-03-01

    Full Text Available Average income per capita is one of the main indicators of the standard of living. This indicator is widely used in research devoted to poverty, interregional income inequality, and is also the main reference point of success of pursued regional policies. A number of researchers note poor quality of official data on household income and call into question their reliability in some regions of Russia. The main reasons include the following: the scale of shadow economy, especially at the level of some regions; insufficient state financing of respective research; and outdated statistical methods of data processing. The author offers the method of quality checking of official statistical data on income per capita by means of a number of indirect indicators. Application of this method also allows receiving alternative estimates of the average per capita income of the population in regions of the country. On the basis of data for 2013-2014 it is shown that in a number of regions official statistical data are underestimated by more than 20%. The received alternative estimates of the average per capita income can be used in further research in place of official indicators

  3. Nuevos bivalvos para el Perú en Bahía Independencia

    Directory of Open Access Journals (Sweden)

    Oswaldo Cornejo

    2013-06-01

    Full Text Available Se registran por primera vez para el Perú las siguientes especies de bivalvos Nucula (Nucula pisum Sowerby I, 1833, y Lyonsia delicata Marincovich, 1973, colectadas en Bahía Independencia, Pisco, Perú, en el 2002.

  4. Deletion of circadian gene Per1 alleviates acute ethanol-induced hepatotoxicity in mice

    International Nuclear Information System (INIS)

    Wang, Tao; Yang, Ping; Zhan, Yibei; Xia, Lin; Hua, Zichun; Zhang, Jianfa

    2013-01-01

    The severity of ethanol-induced liver injury is associated with oxidative stress and lipid accumulation in the liver. Core circadian clock is known to mediate antioxidative enzyme activity and lipid metabolism. However, the link between circadian clock and ethanol-induced hepatotoxicity remains unclear. Here we showed that extents of acute ethanol-induced liver injury and steatosis in mice exhibit circadian variations consistent with hepatic expression of Period (Per) genes. Mice lacking clock gene Per1 displayed less susceptible to ethanol-induced liver injury, as evidenced by lower serum transaminase activity and less severe histopathological changes. Ethanol-induced lipid peroxidation was alleviated in Per1−/− mice. However, Per1 deletion had no effect on antioxidants depletion caused by ethanol administration. Ethanol-induced triglycerides (TG) accumulation in the serum and liver was significantly decreased in Per1−/− mice compared with that in wild-type (WT) mice. Analysis of gene expression in the liver revealed peroxisome proliferators activated receptor-gamma (PPARγ) and its target genes related to TG synthesis are remarkably down-regulated in Per1−/− mice. HepG2 cells were treated with ethanol at 150 mM for 3 days. Per1 overexpression augmented lipid accumulation after treatment with ethanol in HepG2 cells, but had no effect on ethanol-induced oxidative stress. Expression of genes related to lipogenesis, including PPARγ and its target genes, was up-regulated in cells overexpressing Per1. In conclusion, these results indicated that circadian rhythms of ethanol-induced hepatotoxicity are controlled by clock gene Per1, and deletion of Per1 protected mice from ethanol-induced liver injury by decreasing hepatic lipid accumulation

  5. Per un dizionario della ricerca sul Technology Enhanced Learning

    Directory of Open Access Journals (Sweden)

    Nicolas Balacheff

    2012-12-01

    Full Text Available Questo articolo presenta le principali linee di azione di un meta-progetto iniziato nell’ambito della Rete di Eccellenza STELLAR con l’obiettivo di creare e dare struttura a un Thesaurus e a un Dizionario dei termini e delle espressioni in uso nell’ambito della ricerca sul Technology Enhanced Learning (TEL. Questo meta-progetto intende fornire gli strumenti per superare le difficoltà dovute alla ricchezza e alla rapida evoluzione di quest’area di ricerca multidisciplinare, allo scopo di facilitare il coinvolgimento dei ricercatori giovani e di quelli che si accostano per la prima volta a questo settore, nonché di tutti coloro che a vario titolo si interessano al TEL. Il meta-progetto in questione ha anche l’ambizione di facilitare la comunicazione tra individui appartenenti a diverse culture scientifiche e tra le lingue nazionali. Dopo una presentazione delle motivazioni, vengono discussi gli attuali sviluppi del lavoro e presentati i criteri seguiti per le principali scelte effettuate in merito ai metodi e alle tecnologie utilizzate.

  6. Application of the index WQI-CCME with data aggregation per monitoring campaign and per section of the river: case study-Joanes River, Brazil.

    Science.gov (United States)

    de Almeida, Geane Silva; de Oliveira, Iara Brandão

    2018-03-07

    This work applied the Water Quality Index developed by the Canadian Council of Ministers of the Environment (WQI-CCME), to communicate the water quality per section of the Joanes River basin, State of Bahia, Brazil. WQI-CCME is a statistical procedure that originally requires the execution of at least four monitoring campaigns per monitoring location and the measurement of at least four parameters. This paper presents a new aggregation method to calculate the WQI-CCME because, to apply the original method in Joanes River, a huge loss of information would occur, by the fact that, the number of analyzed parameters varied between the monitoring campaigns developed by the Government Monitoring Program. This work modified the original aggregation method replacing it by a data aggregation for a single monitoring campaign, in a minimum of four monitoring locations per section of the river and a minimum of four parameters per monitoring location. Comparison between the calculation of WQI-CCME for river sections, with the index, WQI-CETESB, developed by the Brazilian Environmental Sanitation and Technology Company-CETESB, proved the applicability of the new aggregation method. The WQI-CETESB has it bases on the WQI from the National Sanitation Foundation and uses nine fixed parameters. As WQI-CCME uses the totality of the analyzed parameters without restrictions, it is more flexible, and the results seem more adequate to indicate the real river water quality. However, the WQI-CCME has a more stringent water quality scale in comparison with the WQI-CETESB, resulting in inferior water quality information. In conclusion, the WQI-CCME with a new aggregation method is adequate for communicating the water quality at a given time, per section of a river, respecting the minimum number of four analyses and four monitoring points. As a result, without a need to wait for other campaigns, it reduces the cost of a monitoring program and the period to communicate the water quality. The

  7. Green economy: un'occasione per le aree montane

    Directory of Open Access Journals (Sweden)

    Maria Sapone

    2013-06-01

    Full Text Available È ormai opinione largamente condivisa che l’attuale “crisi” dell’organismo territoriale non sia soltanto economica ma anche ambientale. Quest’ultima tematica unita a quella della green economy potrebbero rappresentare l'occasione di intervenire sui sistemi territoriali non urbani, un tempo vitali per l’economia locale, ed oggi abbandonati a se stessi a favore delle aree urbanizzate, luoghi economicamente più vantaggiosi. Partendo dalle indicazioni del Programma per l’Ambiente delle Nazioni Unite (UNEP si potrebbero definire politiche di sviluppo al fine di migliorare la competitività e l'attrattività dei sistemi territoriali rurali attraverso la valorizzazione delle risorse endogene presenti su tali territori, con l’obiettivo di favorire lo sviluppo ecosostenibile delle diverse attività al fine di creare una rete integrata. La ricerca svolta presenta le diverse dinamiche legate alla creazione di una rete di Eco-Villaggi, con lo scopo di rifunzionalizzare il patrimonio edilizio e urbanistico esistente, migliorando, così, la qualità della vita dei centri montani. Questo modello può rappresentare concretamente una delle possibili soluzioni allo spopolamento, nel conservare e tutelare lo spazio naturale attraverso la promozione della green economy, basata sull’utilizzo di sistemi di produzione sostenibili, nel rispetto dei requisiti ambientali, nell’attivazione di sistemi energetici rinnovabili e nel richiamo turistico del patrimonio storico-culturale della montagna. Infatti queste risorse se gestite nel modo corretto, attraverso una attenta pianificazione territoriale, potrebbero rappresentare il volano per un modello di sviluppo sostenibile e allo stesso tempo potrebbero avviare una riqualificazione e valorizzazione dei borghi rurali, che spesso ospitano un patrimonio architettonico di notevole pregio. Risulta necessario, per i contesti rurali, porre in atto strumenti, modalità e forme innovative d’intervento capaci

  8. Persönlichkeit und Belastungs- bzw. Ressourcenfaktoren. Eine multivariate Betrachtung

    OpenAIRE

    Schneider, Benno

    1997-01-01

    In verschiedenen Modellvorstellungen wird der Zusammenhang zwischen Persönlichkeitseigenschaften und subjektiv erlebtem Streß immer wieder postuliert. Die Forschung ging dabei immer nur einzelnen Variablen nach. Diese Arbeit untersucht den Zusammenhang zwischen einer mehrdimensional erhobenen Persönlichkeit und die mit einem Screeningverfahren erfaßten belastende Ereignisse, soziale Unterstützung und objektiv erlebte positiven oder negative Lebensereignisse. Es wurden über 420 Patienten aus A...

  9. Acerca del nombre del Perú en la actual Colombia

    Directory of Open Access Journals (Sweden)

    Juan Friede

    1962-03-01

    Full Text Available Como es sabido, la adaptación del nombre "Perú" al Imperio Incaico es de origen netamente español. Los indios del Perú no llamaban así a su territorio, como lo confirman Valera, Cieza de León, Montesinos, Garcilaso y otros. Tenían nombres para designar las distintas provincias pero no para la totalidad del imperio de los incas.

  10. Informazioni geografiche per i Location Based Services

    Directory of Open Access Journals (Sweden)

    Renzo Carlucci

    2008-03-01

    Full Text Available Elaborazione digitale della posizione umana e delle sue necessità: è un tentativo di traduzione del termine LBS Location Based Services, servizi basati sulla localizzazione. Un classico esempio? Il navigatore per autovetture, o Tom Tom dal nome del costruttore più diffuso. Un accessorio diffuso quasi al pari del telefono cellulare.

  11. Design and analysis of helium Brayton power cycles for HiPER reactor

    Energy Technology Data Exchange (ETDEWEB)

    Sánchez, Consuelo, E-mail: csanchez@ind.uned.es [Dpto. Ingeniería Energética UNED, Madrid (Spain); Juárez, Rafael; Sanz, Javier [Dpto. Ingeniería Energética UNED, Madrid (Spain); Instituto de Fusión Nuclear/UPM, Madrid (Spain); Perlado, Manuel [Instituto de Fusión Nuclear/UPM, Madrid (Spain)

    2013-10-15

    Highlights: ► A helium Brayton cycle has been designed integrating the two energy sources of HiPER. ► The Brayton cycle has intercooling stages and a recovery process. ► The low temperature of HiPER heat sources results in low cycle efficiency (35.2%). ► Two inter-cooling stages and a reheating process increases efficiency to over 37%. ► Helium Brayton cycles are to be considered as candidates for HiPER power cycles. -- Abstract: Helium Brayton cycles have been studied as power cycles for both fission and fusion reactors obtaining high thermal efficiency. This paper studies several technological schemes of helium Brayton cycles applied for the HiPER reactor proposal. Since HiPER integrates technologies available at short term, its working conditions results in a very low maximum temperature of the energy sources, something that limits the thermal performance of the cycle. The aim of this work is to analyze the potential of the helium Brayton cycles as power cycles for HiPER. Several helium Brayton cycle configurations have been investigated with the purpose of raising the cycle thermal efficiency under the working conditions of HiPER. The effects of inter-cooling and reheating have specifically been studied. Sensitivity analyses of the key cycle parameters and component performances on the maximum thermal efficiency have also been carried out. The addition of several inter-cooling stages in a helium Brayton cycle has allowed obtaining a maximum thermal efficiency of over 36%, and the inclusion of a reheating process may also yield an added increase of nearly 1 percentage point to reach 37%. These results confirm that helium Brayton cycles are to be considered among the power cycle candidates for HiPER.

  12. Design and analysis of helium Brayton power cycles for HiPER reactor

    International Nuclear Information System (INIS)

    Sánchez, Consuelo; Juárez, Rafael; Sanz, Javier; Perlado, Manuel

    2013-01-01

    Highlights: ► A helium Brayton cycle has been designed integrating the two energy sources of HiPER. ► The Brayton cycle has intercooling stages and a recovery process. ► The low temperature of HiPER heat sources results in low cycle efficiency (35.2%). ► Two inter-cooling stages and a reheating process increases efficiency to over 37%. ► Helium Brayton cycles are to be considered as candidates for HiPER power cycles. -- Abstract: Helium Brayton cycles have been studied as power cycles for both fission and fusion reactors obtaining high thermal efficiency. This paper studies several technological schemes of helium Brayton cycles applied for the HiPER reactor proposal. Since HiPER integrates technologies available at short term, its working conditions results in a very low maximum temperature of the energy sources, something that limits the thermal performance of the cycle. The aim of this work is to analyze the potential of the helium Brayton cycles as power cycles for HiPER. Several helium Brayton cycle configurations have been investigated with the purpose of raising the cycle thermal efficiency under the working conditions of HiPER. The effects of inter-cooling and reheating have specifically been studied. Sensitivity analyses of the key cycle parameters and component performances on the maximum thermal efficiency have also been carried out. The addition of several inter-cooling stages in a helium Brayton cycle has allowed obtaining a maximum thermal efficiency of over 36%, and the inclusion of a reheating process may also yield an added increase of nearly 1 percentage point to reach 37%. These results confirm that helium Brayton cycles are to be considered among the power cycle candidates for HiPER

  13. Màquina omplidora semiautomàtica per zona ATEX

    OpenAIRE

    Tiñena Guiamet, Jaume

    2014-01-01

    En aquest projecte es realitza una màquina omplidora semiautomàtica per a zones ATEX (Appareils destinés à êtreutilisés en ATmosphères EXplosives). Aquesta màquina té la capacitat d’omplir tot tipus de recipients amb capacitats des de 20 fins a 1500 litres. Perquè aquest procés sigui possible, un sistema de transportadors desplaça el palet buit fins la zona de dosificació, lloc on l’operari posiciona manualment el dosificador per posteriorment iniciar el cicle d’emplenat automàtic. L’opera...

  14. Characterizing Energy per Job in Cloud Applications

    Directory of Open Access Journals (Sweden)

    Thi Thao Nguyen Ho

    2016-12-01

    Full Text Available Energy efficiency is a major research focus in sustainable development and is becoming even more critical in information technology (IT with the introduction of new technologies, such as cloud computing and big data, that attract more business users and generate more data to be processed. While many proposals have been presented to optimize power consumption at a system level, the increasing heterogeneity of current workloads requires a finer analysis in the application level to enable adaptive behaviors and in order to reduce the global energy usage. In this work, we focus on batch applications running on virtual machines in the context of data centers. We analyze the application characteristics, model their energy consumption and quantify the energy per job. The analysis focuses on evaluating the efficiency of applications in terms of performance and energy consumed per job, in particular when shared resources are used and the hosts on which the virtual machines are running are heterogeneous in terms of energy profiles, with the aim of identifying the best combinations in the use of resources.

  15. The Analysis of Income per Capita Convergence on ASEAN Plus Three (APT Countries

    Directory of Open Access Journals (Sweden)

    Any Fatiwetunusa

    2017-09-01

    Full Text Available The main objective of this study is to test the convergence of income per capita in APT countries through three models: absolute convergence, conditional convergence and sigma convergence. Regression analysis of panel data from 13 APT countries during the period of 2001-2014 is used to analysed to study problem. In absolute convergence model, the growth of real GDP per capita and initial real GDP are used as the variables, meanwhile, 8 variables such as the growth of real GPD per capita, initial real GDP per capita, labor force ratio, value added in agricultural sector, value added in industrial sector, terms of trade, foreign direct investment and internet users ratio are analyzed in conditional convergence model. According to the Solow model, the economies of the countries will converge in which the growth of income per capita of developing countries will be higher than those of developed countries. The economies will be convergent if the countries tend to move to a similar steady state resulting in smaller gap between the countries. Based on the results of absolute convergence and conditional convergence models, APT countries is converging with the rate of 2% and 2.2%. This is consistent with the results of sigma convergence model that shows a declining trend in the dispersion of real GDP per capita in APT regions. The growth of real GDP per capita is influenced by initial GDP per capita, labor force ratio, value added in agricultural sector, value added in industrial sector, terms of trade, foreign direct investment and internet users ratio. Developed countries such as Singapore, Brunei Darussalam and South Korea experience the impact of high real GDP per capita growth. On the contrary, Indonesia, Laos, Vietnam and The Phillipines undergo the impact of low GDP per capita growth.

  16. The peronism of Perón and Menem

    OpenAIRE

    Waldmann, Peter

    1993-01-01

    The peronism of Perón and Menem : from justicialism to liberalism? - In: Argentina in the crisis years (1983-1990) / ed. by Colin M. Lewis ... - London : Inst. of Latin American Studies, 1993. - S. 90-101

  17. Hi ha un paper per a l'ètica a l'empresa?

    OpenAIRE

    Argandoña Rámiz, Antonio

    2001-01-01

    No hi ha decisions ètiques i decisions no ètiques. Hi ha decisions: l'ètica és, simplement, un component més de cada decisió —i, per tant, molt important. No hi ha directors d'empresa ètics i altres que no ho són: hi ha directors que dirigeixen bé, i directors que dirigeixen malament. Els que dirigeixen bé són ètics. Si no són ètics, estan perdent algun aspecte de la realitat que és necessari per a la seva tasca de dirigir: per tant, dirigeixen malament. Però, a més a més, ser ètic no és tan ...

  18. Glossario per la città europea / Glossary for the European city

    Directory of Open Access Journals (Sweden)

    Yannis Tsiomis

    2014-09-01

    Full Text Available Il concetto di “città in estensione” di Giuseppe Samonà è l'occasione per riflettere sul significato del fenomeno urbano oggi. L’autore lo fa attraverso nove punti, da “estensione” a “polisemia”, passando per “scala”, “metodo” e “funzione”, che diventano i termini di un nuovo glossario ragionato per la città europea, per un approccio cosciente allo studio e al progetto di quello che lui chiama “il dilemma territoriale”. / Giuseppe Samonà's idea of the "city in extension" offers the occasion to reflect on the meaning of the urban phenomenon today. The author does so through nine points, from “extension” to “polysemy”, passing via “scale”, “method” and “function”, which become the terms of a new reasoned glossary for the European city, for an aware approach to studio and the project of what he calls “the territorial dilemma”.

  19. Platelet density per monocyte predicts adverse events in patients after percutaneous coronary intervention.

    Science.gov (United States)

    Rutten, Bert; Roest, Mark; McClellan, Elizabeth A; Sels, Jan W; Stubbs, Andrew; Jukema, J Wouter; Doevendans, Pieter A; Waltenberger, Johannes; van Zonneveld, Anton-Jan; Pasterkamp, Gerard; De Groot, Philip G; Hoefer, Imo E

    2016-01-01

    Monocyte recruitment to damaged endothelium is enhanced by platelet binding to monocytes and contributes to vascular repair. Therefore, we studied whether the number of platelets per monocyte affects the recurrence of adverse events in patients after percutaneous coronary intervention (PCI). Platelet-monocytes complexes with high and low median fluorescence intensities (MFI) of the platelet marker CD42b were isolated using cell sorting. Microscopic analysis revealed that a high platelet marker MFI on monocytes corresponded with a high platelet density per monocyte while a low platelet marker MFI corresponded with a low platelet density per monocyte (3.4 ± 0.7 vs 1.4 ± 0.1 platelets per monocyte, P=0.01). Using real-time video microscopy, we observed increased recruitment of high platelet density monocytes to endothelial cells as compared with low platelet density monocytes (P=0.01). Next, we classified PCI scheduled patients (N=263) into groups with high, medium and low platelet densities per monocyte and assessed the recurrence of adverse events. After multivariate adjustment for potential confounders, we observed a 2.5-fold reduction in the recurrence of adverse events in patients with a high platelet density per monocyte as compared with a low platelet density per monocyte [hazard ratio=0.4 (95% confidence interval, 0.2-0.8), P=0.01]. We show that a high platelet density per monocyte increases monocyte recruitment to endothelial cells and predicts a reduction in the recurrence of adverse events in patients after PCI. These findings may imply that a high platelet density per monocyte protects against recurrence of adverse events.

  20. CALiPER Year in Review 2012

    Energy Technology Data Exchange (ETDEWEB)

    None

    2012-12-10

    The CALiPER program has tested more than 500 products since its inception in 2006, revealing a variety of performance trends, holding manufacturers accountable for claims, and identifying concerns that limit adoption. Over the past six years, the LED marketplace has changed substantially; previously relegated to niche status, LED products are now a viable alternative in many product categories and market share is expected to grow rapidly. This document summarizes recent testing results and provides an overview of multiyear trends.

  1. Noves tècniques d'interacció per a entorns virtuals

    OpenAIRE

    Soler Pastó, Artur

    2010-01-01

    Estudi de noves tècniques d'interacció per a entorns virtuals. El projecte es basa en l'anàlisi del dispositiu d'interacció ment-computador Emotiv EPOC, i inclou el desenvolupament d'un prototip d'un entorn virtual per a realitzar els estudis necessaris.

  2. 38 CFR 51.43 - Per diem and drugs and medicines-principles.

    Science.gov (United States)

    2010-07-01

    ... medicines-principles. 51.43 Section 51.43 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS... Per diem and drugs and medicines—principles. (a) As a condition for receiving payment of per diem... at the nursing home. Relevant cost principles are set forth in the Office of Management and Budget...

  3. Del “Perón Vuelve” al día que Perón volvió. Ezeiza 1973, percepciones de un regreso

    Directory of Open Access Journals (Sweden)

    Fonte, Leonardo Mario

    2014-12-01

    Full Text Available Resumen Este trabajo se ocupa de analizar una serie de cuestiones que se desprenden de los sucesos ocurridos en Ezeiza, el 20 de junio de 1973, en el contexto de la vigilia por el regreso a la Argentina de Juan Domingo Perón. En tal sentido, en primer lugar se pretenderá definir si la conceptualización “masacre”, semánticamente, mantiene un correlato con los eventos desarrollados durante esa jornada. En segundo lugar, se buscará analizar si es posible aseverar, que la izquierda peronista en su conjunto fue la víctima ingenua de una matanza perpetrada intencionalmente para desplazar a Cámpora y copar el poder. Por último, se tratará de examinar cómo el 20 de junio de 1973, se evidenciaron las contradicciones existentes entre la conducción de Montoneros y Perón, y cómo estas diferencias acabaron cristalizándose en los incidentes ocurridos. Abstract This work focuses on analyzing a series of issues that took place during June 20th 1973 in Ezeiza in the context of the eve for the return of Juan Domingo Perón to Argentina. In first place, it will be attempted to define if the concept of “Massacre”, in a semantic way, keeps a correlation with the events that developed during that day. Secondly, an analysis will be made to see if it is possible to asseverate that the “Peronist left-wing movement” was an innocent victim of a bloodbath made intentionally to displace Cámpora and take the power. Finally, we will examine how on June 20th 1973 the contradictions between Montoneros and Perón became evident and how these differences, in the end, were reflected in the incidents.

  4. Registro adicional de Langea euprosopides (Coleoptera: Cicindelidae para el Perú

    Directory of Open Access Journals (Sweden)

    Abdhiel Arnaldo Bustamante-Navarrete

    2016-12-01

    Full Text Available Se registra un nuevo espécimen de Langea euprosopides W. Horn, 1901 en la región Cusco (Perú. El género Langea W. Horn contiene tres especies. Debido a la falta de observaciones de miembros de este género en su ambiente natural, se desconocen sus hábitos, ciclo biológico y sus estadios de ciclo de vida. El género es aparentemente endémico del Perú. Se presentan algunos datos sobre el posible sustrato de captura y un mapa de distribución de la especie en el Perú.

  5. Per-Olov Löwdin - father of quantum chemistry

    Science.gov (United States)

    Brändas, Erkki J.

    2017-09-01

    During 2016, we celebrate the 100th anniversary of the birth of Per-Olov Löwdin. He was appointed to the first Lehrstuhl in quantum chemistry at Uppsala University in 1960. Löwdin introduced quantum chemistry as a field in its own right by formulating its goals, establishing fundamental concepts, like the correlation energy, the method of configuration interaction, reduced density matrices, natural spin orbitals, charge and bond order matrices, symmetric orthogonalisation, and generalised self-consistent fields. His exposition of partitioning technique and perturbation theory, wave and reaction operators and associated non-linear summation techniques, introduced mathematical rigour and deductive order in the interpretative organisation of the new field. He brought the first computer to Uppsala University and pioneered the initiation of 'electronic brains' and anticipated their significance for quantum chemistry. Perhaps his single most influential contribution to the field was his education of two generations of future faculty in quantum chemistry through Summer Schools in the Scandinavian Mountains, Winter Institutes at Sanibel Island in the Gulf of Mexico. Per-Olov Löwdin founded the book series Advances in Quantum Chemistry and the International Journal of Quantum Chemistry. The evolution of quantum chemistry is appraised, starting from a collection of cross-disciplinary applications of quantum mechanics to the technologically advanced and predominant field of today, virtually used in all branches of chemistry. The scientific work of Per-Olov Löwdin has been crucial for the development of this new important province of science.

  6. The SKI-project External events - Phase 2. Estimation of fire frequencies per plant and per building

    International Nuclear Information System (INIS)

    Poern, K.

    1996-08-01

    The Swedish-Finnish handbook for initiating event frequencies, I-Book, does not contain any fire frequencies. This matter of fact is not defensible considering the substantial risk contribution caused by fires. In the PSAs performed hitherto the initiating fire frequencies have been determined from case to case. Because data are usually very scarce in these areas it is very important to develop unique definitions, to systematically utilize both international and national experiences and to establish an appropriate statistical estimation method. It is also important to present the accumulated experience such that it can be used for different purposes, not only within PSA but also in the concrete fire preventive work. During phase 1 of the project External Events an inventory was made of existing methods for probabilistic fire analysis in general. During phase 2 of the project it was decided to initialize the work on a complementary handbook, called X-Book, in order to encompass the frequencies of system external events, i.e. initiating events that are caused by events occurring outside the system boundaries. In Version 1 of the X-Book the attention is mainly focussed on the estimation of initiating fire frequencies, per plant and per building. This estimation is basically founded on reports that the power companies have collected for this specific purpose. This report describes the statistical model and method that have been used in the estimation process. The methodological results achieved may, possibly after some modification, be applicable also to other types of system external events

  7. Per and polyfluorinated substances in the Nordic Countries

    DEFF Research Database (Denmark)

    Posner, Stefan; Roos, Sandra; Brunn Poulsen, Pia

    This Tema Nord report presents a study based on open information and custom market research to review the most common perfluorinated substances (PFC) with less focus on PFOS and PFOA. The study includes three major parts: 1) Identification of relevant per-and polyfluorinated substances and their ......This Tema Nord report presents a study based on open information and custom market research to review the most common perfluorinated substances (PFC) with less focus on PFOS and PFOA. The study includes three major parts: 1) Identification of relevant per-and polyfluorinated substances...... and their use in various industrial sectors in the Nordic market by interviews with major players and database information 2) Emissions to and occurence in the Nordic environment of the substances described in 1) 3) A summary of knowledge of the toxic effects on humans and the environment of substances...

  8. Sociosemiotica e generi comunicativi: una proposta per analizzare la comunicazione nel web

    Directory of Open Access Journals (Sweden)

    Nicola Cavalli

    2003-12-01

    Full Text Available Il web può essere definito come uno spazio antropologico, uno spazio di significati caratterizzato dalla rivoluzione dei concetti spazio/temporali. Per analizzare la comunicazione web con un modello che possa essere valido anche per altri tipi di comunicazione viene proposto l'approccio sociosemiotico. In quest'ambito viene sviluppato il concetto di genere comunicativo, che vuole essere la chiave per analizzare la comunicazione e trarre indicazioni sulle carateristiche sociali della comunità di riferimento.

  9. Documenti per una storia dell'ospedale di Santa Maria della Scala di Siena

    Directory of Open Access Journals (Sweden)

    Gabriella Piccinni

    2013-12-01

    Full Text Available L’ospedale senese di Santa Maria della Scala si propone alla riflessione europea: per l’imponenza e la ricchezza artistica dell’edificio e per la fortissima identità civica di cui è portatore, dalla sua centralità materiale e simbolica nel tessuto urbano; per l’efficacia delle soluzioni e dell’impianto economico di supporto all’assistenza; per essere stato, dalla fine del Trecento, preso a modello in Italia e in Europa. E, infine, che è quello che più direttamente interessa qui, per la consistenza, varietà e potenzialità del suo patrimonio documentario. Dopo avere illustrato la struttura della documentazione, composta di 6.849 unità (dal 1240 al 1930 e da 5.566 pergamene del fondo diplomatico (dal 1194 al 1725 si richiama l’attenzione sulle potenzialità della documentazione ospedaliera di divenire fonte per la storia della società, dell’economia, delle istituzioni e della politica: tutto ciò attraverso esempi tratti dalla documentazione senese ma pensando che possano servire anche in una prospettiva comparativa più generale. Nel richiamare l’attenzione sul ruolo rivestito dagli ospedali all’interno del sistema sociale, economico e politico sul quale si reggevano le città italiane degli ultimi secoli del Medioevo, e nel dirigere lo sguardo verso l’economia dell’assistenza, Siena può, infatti, dire qualcosa di nuovo, proprio per la particolare ricchezza documentaria e per alcuni caratteri della sua storia e della sua economia.

  10. Real Estate Crowdfunding. Un’innovazione finanziaria per gli investimenti immobiliari

    Directory of Open Access Journals (Sweden)

    Giacomo Morri

    2016-12-01

    Full Text Available Questo articolo presenta una panoramica del crowdfunding e delle sue potenziali applicazioni al settore immobiliare. La crisi economica globale del 2008 ha condotto a una paralisi dell’economia che ha comportato la riduzione della fiducia nel sistema bancario e nei servizi finanziari in generale. Nell’ultimo decennio una delle tecniche di finanziamento più rivoluzionaria è stata il crowdfunding, cioè la possibilità di essere finanziati dalla “folla” (crowd attraverso l’utilizzo di Internet. Il crowdfunding nel settore immobiliare ha origine negli Stati Uniti nel 2012 con il Jumpstart Our Business Start-up Act (JOBS Act, dove da allora si sta sviluppando a ritmi elevati. In Italia, il crowdfunding per progetti nel settore immobiliare non si è ancora sviluppato in quanto la legge in concreto non ne consente l’utilizzo; tuttavia esistono alcune piattaforme che stanno utilizzando il concetto in modi differenti, raccogliendo un certo interesse. Il Real Estate Crowdfunding può rappresentare un’interessante opportunità per i privati che vogliono investire nel settore immobiliare, ma non hanno abbastanza capitale per partecipare a grandi transazioni o esperienza nella gestione. In quest’articolo, dopo un’iniziale descrizione del crowdfunding in generale, ci si focalizza sulla sua applicazione nel settore immobiliare, analizzando il mercato statunitense dove vi sono le piattaforme più sviluppate. Infine, si presenta una panoramica del mercato italiano, spiegando le normative e i limiti del crowdfunding e descrivendo la modalità operativa sviluppata da alcune piattaforme per superare legalmente tali limitazioni. Negli Stati Uniti sono già operative oltre 125 piattaforme con una raccolta superiore a un miliardo di dollari; in Italia invece ci sono ancora limiti per le start-up che si occupano di crowdfunding e sono state create solo poche piattaforme che operano con un modello parzialmente diverso.

  11. The Effect of Different Photoperiods in Circadian Rhythms of Per3 Knockout Mice

    Directory of Open Access Journals (Sweden)

    D. S. Pereira

    2014-01-01

    Full Text Available The aim of this study was to analyse the circadian behavioural responses of mice carrying a functional knockout of the Per3 gene (Per3−/− to different light : dark (L : D cycles. Male adult wild-type (WT and Per3−/− mice were kept under 12-hour light : 12-hour dark conditions (12L : 12D and then transferred to either a short or long photoperiod and subsequently released into total darkness. All mice were exposed to both conditions, and behavioural activity data were acquired through running wheel activity and analysed for circadian characteristics during these conditions. We observed that, during the transition from 12L : 12D to 16L : 8D, Per3−/− mice take approximately one additional day to synchronise to the new L : D cycle compared to WT mice. Under these long photoperiod conditions, Per3−/− mice were more active in the light phase. Our results suggest that Per3−/− mice are less sensitive to light. The data presented here provides further evidence that Per3 is involved in the suppression of behavioural activity in direct response to light.

  12. Ipotesi per l'attore del futuro

    Directory of Open Access Journals (Sweden)

    Marco Galignano

    2012-01-01

    Full Text Available Abstract – IT Il teatro è in subbuglio perché il mondo tutto è in subbuglio. Ciclicità probabilmente, nel presente difficile. Crisi. Storiografia, società, umanità, nuove forme di teatro, scontro/incontro di etnologie, scienza nuova in fermento (biologia, fisica, chimica, tecnologia, astronomia, nuovi orizzonti di conoscenza, attori che si cercano, contaminazioni artistiche di genere, pedagogie da rifare. Caos. Tradizioni sconvolte e nuove necessità. Economia allo spasmo. Eppure esiste una strada positiva, attuabile nella sfera del privato, del personale. La salute, intesa come scopo di esistenza; la poesia, in connessione con il mistero ontologico; l’arte, specchio e riflesso della vita, potrebbero essere i capisaldi di una nuova integrazione, psicofisica, volta alla riscoperta del naturale, del benessere umano. Si cerca qui di proporre delle strade che vadano in questa direzione. Ipotesi di vita, per il teatro, per l’attore. Per l’essere umano nel nuovo millennio. Ipotesi su come possano fondersi le conoscenze più avanzate sulla salute organica dell’essere umano, recuperando la sapienza antica a volte incomprensibilmente dimenticata; la parte più aulica, nel senso di elevata, raffinata e funzionale dell’arte dello spettacolo. Abstract – EN Theatre is in a turmoil, because the whole world is in a turmoil. Cyclical pattern, perhaps, in a difficult present time. Crisis. Historiography, society, humankind, new ways of making theatre, ethnological encounter and clashing, new science in a state of ferment (biology, physics, chemistry, technology, astronomy, new horizons of knowledge, actors in search of each other, artistic gender contamination, science of education to be built anew. Chaos. Upset tradition and new needs. Suffering economy. Nevertheless, a positive way does exist and it’s workable in your own personal environment. Health meant as a goal of existence, poetry connected with ontological mystery and art as a

  13. The concept of ’Musa-pelo and the medicinal use of shrubby legumes (Fabaceae in Lesotho

    Directory of Open Access Journals (Sweden)

    A. Moteetee

    2007-08-01

    Full Text Available In the Kingdom of Lesotho, 20 plant species are commonly known as  'Musa-pelo. The term literally means ‘the one who brings back or tums around the heart’.  'Musa-pelo is traditionally used as a sedative and is given as a first aid treatment to bereaved people who are under severe psychological duress or stress. Of the 20 species known as  'Musa-pelo, 17 belong to nine genera of the Fabaceae  (Argyrolobium, Crotalaria, Indigofera, Lessertia, Lotononis, Melolobium, Sutherlandia, Tephrosia and  Trifolium. The three remaining species namely Cleome monophylla, Heliophila carnosa and  Cysticapnos pruinosa, belong to the families Capparaceae, Brassicaceae and Fumariaceae, respectively. In this paper, the concept of 'Musa-pelo in traditional medicine is explored.

  14. Half a dollar per kWh and still cheap electricity

    International Nuclear Information System (INIS)

    Daey Ouwens, C.

    1991-01-01

    An analysis for the costs of electricity produced by an autonomous solar cell system in combination with efficient electric appliances, as they are used in houses and small offices, is presented. If efficient appliances are used, an average household will use about 700 kWh per year, compared to about 3000 kWh it is using on average at present. Efficient appliances, however, are more expensive. The extra cost per kWh saved is about the same as the cost of the fuel needed to produce a kWh in a power plant. The 700 kWh per year can be produced by an autonomous solar cell system with an area of 3 m 2 (efficiency 19%). The analysis is valid roughly for the area between 40 o northern and southern latitude. A comparison has been made between the total costs of a grid connection and the costs of an autonomous solar cell system. If all costs are capitalized and compiled, a grid connection will amount to about $6,000 (fuel costs are not included). The costs of a solar cell system producing 700 kWh per year are about the same or even lower. The modular nature of solar cell systems makes it possible to start with a certain number of appliances, depending on the amount of money one can spend. 6 tabs., 2 refs

  15. Scripting Fonetico nuove risorse per leggere il greco antico mediante la sintesi vocale

    Directory of Open Access Journals (Sweden)

    Silvia Gianferrari

    2011-04-01

    Full Text Available Lo scripting fonetico da lingua italiana produce finalmente una sintesi vocale del greco antico senz’altro soddisfacente per gli usi didattici della Scuola secondaria, per l’accesso alle banche dati che raccolgono l’intero patrimonio letterario della lingua antica e per l’editoria digitale costruita secondo i parametri dell’accessibilità.

  16. Multiple 60-Minute Massages per Week Offer Relief for Chronic Neck Pain

    Science.gov (United States)

    ... W X Y Z Multiple 60-Minute Massages per Week Offer Relief for Chronic Neck Pain Share: © ... funded study found that multiple 60-minute massages per week were more effective than fewer or shorter ...

  17. Licensing Uncertain Patents: Per-Unit Royalty vs Up-Front Fee

    OpenAIRE

    Encaoua , David; Lefouili , Yassine

    2008-01-01

    ED EPS; In this paper we examine the implications of uncertainty over patent validity on patentholders' licensing strategies. Two licensing mechanisms are examined: per-unit royalty and up-front fee.We provide conditions under which uncertain patents are licensed in order to avoid patent litigation. It is shown that while it is possible for the patentholder to reap som e "extra profit" by selling an uncertain patent under the pure per-unit royalty regime, the opportunity to do so does not exi...

  18. Space shuttle solid rocket booster cost-per-flight analysis technique

    Science.gov (United States)

    Forney, J. A.

    1979-01-01

    A cost per flight computer model is described which considers: traffic model, component attrition, hardware useful life, turnaround time for refurbishment, manufacturing rates, learning curves on the time to perform tasks, cost improvement curves on quantity hardware buys, inflation, spares philosophy, long lead, hardware funding requirements, and other logistics and scheduling constraints. Additional uses of the model include assessing the cost per flight impact of changing major space shuttle program parameters and searching for opportunities to make cost effective management decisions.

  19. Interstellar Abundances Toward X Per, Revisited

    Science.gov (United States)

    Valencic, Lynne A.; Smith, Randall K.

    2014-01-01

    The nearby X-ray binary X Per (HD 24534) provides a useful beacon with which to measure elemental abundances in the local ISM. We examine absorption features of 0, Mg, and Si along this line of sight using spectra from the Chandra Observatory's LETG/ ACIS-S and XMM-Newton's RGS instruments. In general, we find that the abundances and their ratios are similar to those of young F and G stars and the most recent solar values. We compare our results with abundances required by dust grain models.

  20. Mujeres invisibles en el Perú

    OpenAIRE

    Sköld, Luz Marina

    2007-01-01

    En el Perú, actualmente existen aproximadamente un millón de personas que no tienen un documento de identidad y no figuran en los registros del Estado. Son consideradas personas invisibles porque no existen le-galmente. De acuerdo a estudios realizados, este grupo de personas tiene un rostro específico; se trata de una población pobre, rural y principal-mente de mujeres. El 53% de las mujeres indocumentadas residen en el área rural. Las causas que originan la indocumentación son varias, entre...

  1. One dose per day compared to multiple doses per day of gentamicin for treatment of suspected or proven sepsis in neonates.

    Science.gov (United States)

    Rao, Shripada C; Srinivasjois, Ravisha; Moon, Kwi

    2016-12-06

    Animal studies and trials in older children and adults suggest that a 'one dose per day' regimen of gentamicin is superior to a 'multiple doses per day' regimen. To compare the efficacy and safety of one dose per day compared to multiple doses per day of gentamicin in suspected or proven sepsis in neonates. Eligible studies were identified by searching the Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 3) in the Cochrane Library (searched 8 April 2016), MEDLINE (1966 to 8 April 2016), Embase (1980 to 8 April 2016), and CINAHL (December 1982 to 8 April 2016). All randomised or quasi-randomised controlled trials comparing one dose per day ('once a day') compared to multiple doses per day ('multiple doses a day') of gentamicin to newborn infants. Data collection and analysis was performed according to the standards of the Cochrane Neonatal Review Group. Eleven RCTs were included (N = 574) and 28 excluded. All except one study enrolled infants of more than 32 weeks' gestation. Limited information suggested that infants in both 'once a day' as well as 'multiple doses a day' regimens showed adequate clearance of sepsis (typical RR 1.00, 95% CI 0.84 to 1.19; typical RD 0.00, 95% CI -0.19 to 0.19; 3 trials; N = 37). 'Once a day' gentamicin regimen was associated with fewer failures to attain peak level of at least 5 µg/ml (typical RR 0.22, 95% CI 0.11 to 0.47; typical RD -0.13, 95% CI -0.19 to -0.08; number needed to treat for an additional beneficial outcome (NNTB) = 8; 9 trials; N = 422); and fewer failures to achieve trough levels of 2 µg/ml or less (typical RR 0.38, 95% CI 0.27 to 0.55; typical RD -0.22, 95% CI -0.29 to -0.15; NNTB = 4; 11 trials; N = 503). 'Once a day' gentamicin achieved higher peak levels (MD 2.58, 95% CI 2.26 to 2.89; 10 trials; N = 440) and lower trough levels (MD -0.57, 95% CI -0.69 to -0.44; 10 trials; N = 440) than 'multiple doses a day' regimen. There was no significant difference in ototoxicity between two groups

  2. INCOME PER BED AS A DETERMINANT OF HOSPITAL’S FINANCIAL LIQUIDITY

    Directory of Open Access Journals (Sweden)

    Agnieszka Bem

    2014-10-01

    Full Text Available Hospitals’ financial condition is very important, in terms of availability and quality of inpatient health care services. Inpatient’s services consume, in Poland, an important part (about 50% of National Health Fund resources, but financial situation of hospitals is difficult and many hospitals report problems with liquidity and solvency. The purpose of this research is to study the relationship between the intensity of care, measured by the annual income per bed, and the static liquidity ratios (current ratio and quick ratio. The research has been conducted on the sample of 138 Polish hospitals, using data covering the period 2009-2011. In order to test research hypotheses, statistical tools have been used (T-Student distribution. The study has shown, that, during analyzed period, liquidity ratios have lowered and the level of financial liquidity is, in case of Polish hospitals, lower than recommended in the literature. The authors also confirmed the existence of the relationship between annual income per bed and liquidity ratios. However, the most important finding is that the relationship between the hospital’s income per bed and financial liquidity ratios is positive only up to a certain level, which has been estimated at about 60,000-70,000 EUR per bed. Above this level further increase in income per bed decreases liquidity ratios. This finding seems to be extremely important for health care managers, which usually strive for the income maximization.

  3. Field evaluation of the biolarvicide, spinosad 20 per cent emulsifiable concentrate in comparison to its 12 per cent suspension concentrate formulation against Culex quinquefasciatus, the vector of bancroftian filariasis in India.

    Science.gov (United States)

    Sadanandane, Candasamy; Gunasekaran, Kasinathan; Boopathi Doss, Ponnusamy Sivagnana; Jambulingam, Purushothaman

    2018-01-01

    Biolarvicides may offer alternatives to chemical larvicides as these are known to be safe to environment and selective against the target species. However, only a limited number of biolarvicides have been approved for mosquito larval control. In the current study, a new formulation of spinosad, 20 per cent emulsifiable concentrate (EC) was tested for its efficacy against Culex quinquefasciatus, in comparison to its 12 per cent suspension concentrate (SC). Spinosad 20 per cent EC was tested against Cx. quinquefasciatus immature at 25, 50, 100 and 150 mg active ingredient (ai)/m [2] in cesspits, drains and abandoned wells in comparison with spinosad 12 per cent SC at the optimum field application dosage of 50 mg ai/m [2] . The 20 per cent EC caused 90-100 per cent reduction of pupal density for 7-14 days in cesspits, 10-17 days in drains and 14-30 days in abandoned wells at all dosages tested. At lower dosages of 25 and 50 mg ai/m [2] , >90 per cent reduction of pupal density was observed for one week in cesspits and street drains and for two weeks in abandoned wells. The effective duration of control provided by the higher dosages, 100 and 150 mg ai/m [2] was 1.4 to 2 times greater than the lower dosages, 25 and 50 mg ai/m [2] . The findings showed that the spinosad 20 per cent EC can be used for larval control against Cx. quinquefasciatus, at the dosage of 25 mg ai/m [2] at weekly interval in cesspits and drains and at fortnightly interval in abandoned wells. Spinosad 20 per cent EC could be one of the options to be considered for larval control under integrated vector management.

  4. A parts-per-billion measurement of the antiproton magnetic moment

    CERN Document Server

    Smorra, C; Borchert, M J; Harrington, J A; Higuchi, T; Nagahama, H; Tanaka, T; Mooser, A; Schneider, G; Blaum, K; Matsuda, Y; Ospelkaus, C; Quint, W; Walz, J; Yamazaki, Y; Ulmer, S

    2017-01-01

    Precise comparisons of the fundamental properties of matter–antimatter conjugates provide sensitive tests of charge–parity–time (CPT) invariance1, which is an important symmetry that rests on basic assumptions of the standard model of particle physics. Experiments on mesons2, leptons3, 4 and baryons5, 6 have compared different properties of matter–antimatter conjugates with fractional uncertainties at the parts-per-billion level or better. One specific quantity, however, has so far only been known to a fractional uncertainty at the parts-per-million level7, 8: the magnetic moment of the antiproton, . The extraordinary difficulty in measuring with high precision is caused by its intrinsic smallness; for example, it is 660 times smaller than the magnetic moment of the positron3. Here we report a high-precision measurement of in units of the nuclear magneton μN with a fractional precision of 1.5 parts per billion (68% confidence level). We use a two-particle spectroscopy method in an advanced cryogenic ...

  5. Primer registro de Florometra magellanica (Bell, 1882 (Echinodermata: Crinoidea para el Perú

    Directory of Open Access Journals (Sweden)

    Elba Prieto Rios

    2011-08-01

    Full Text Available Se registra por primera vez para el Perú al Crinoideo (Echinodermata Florometra magellanica (Bell, 1882. La especie fue recolectada en el talud continental (360 – 814 m frente al departamento de Piura al norte del Perú (3°38,67’S, 81° 2,73’W. El material de referencia se encuentra depositado en la Colección Científica del Instituto del mar del Perú (IMARPE, Lima, Perú y en la Colección Nacional de Equinodermos de la Universidad Nacional Autónoma de México, Ciudad de México.

  6. Response properties of the genetically encoded optical H2O2 sensor HyPer.

    Science.gov (United States)

    Weller, Jonathan; Kizina, Kathrin M; Can, Karolina; Bao, Guobin; Müller, Michael

    2014-11-01

    Reactive oxygen species mediate cellular signaling and neuropathologies. Hence, there is tremendous interest in monitoring (sub)cellular redox conditions. We evaluated the genetically engineered redox sensor HyPer in mouse hippocampal cell cultures. Two days after lipofection, neurons and glia showed sufficient expression levels, and H2O2 reversibly and dose-dependently increased the fluorescence ratio of cytosolic HyPer. Yet, repeated H2O2 treatment caused progressively declining responses, and with millimolar doses an apparent recovery started while H2O2 was still present. Although HyPer should be H2O2 specific, it seemingly responded also to other oxidants and altered cell-endogenous superoxide production. Control experiments with the SypHer pH sensor confirmed that the HyPer ratio responds to pH changes, decreasing with acidosis and increasing during alkalosis. Anoxia/reoxygenation evoked biphasic HyPer responses reporting apparent reduction/oxidation; replacing Cl(-) exerted only negligible effects. Mitochondria-targeted HyPer readily responded to H2O2-albeit less intensely than cytosolic HyPer. With ratiometric two-photon excitation, H2O2 increased the cytosolic HyPer ratio. Time-correlated fluorescence-lifetime imaging microscopy (FLIM) revealed a monoexponential decay of HyPer fluorescence, and H2O2 decreased fluorescence lifetimes. Dithiothreitol failed to further reduce HyPer or to induce reasonable FLIM and two-photon responses. By enabling dynamic recordings, HyPer is superior to synthetic redox-sensitive dyes. Its feasibility for two-photon excitation also enables studies in more complex preparations. Based on FLIM, quantitative analyses might be possible independent of switching excitation wavelengths. Yet, because of its pronounced pH sensitivity, adaptation to repeated oxidation, and insensitivity to reducing stimuli, HyPer responses have to be interpreted carefully. For reliable data, side-by-side pH monitoring with SypHer is essential. Copyright

  7. Sviluppo e valutazione di test diagnostici per la sierodiagnosi di brucellosi suina

    Directory of Open Access Journals (Sweden)

    Tiziana Di Febo

    2012-06-01

    Full Text Available Sono stati sviluppati una ELISA competitiva (c-ELISA, una ELISA indiretta (i-ELISA e un test immunologico DELFIA (Dissociation-Enhanced Lanthanide Fluorescence Immunoassay per la ricerca di anticorpi verso Brucella suis in sieri di maiale e cinghiale. I tre test prevedono l’utilizzo di un anticorpo monoclonale (MAb 4B5A verso l’LPS di Brucella (c-ELISA e DELFIA e di un anticorpo monoclonale (MAb 10C2G5 verso le IgG suine (i-ELISA. La specificità (Sp e la sensibilità (Se dei tre test sono le seguenti: per la c-ELISA Se e Sp = 100% con un valore di cut-off pari al 61.0% (B/B0%; per la i-ELISA Sp = 99.1% e Se = 100% con un valore di cut-off di 21.7% (PP%; per il DELFIA Sp = 91.0% e Se = 75% ponendo il valore di cut-off al 37.0% (B/B0%. Inoltre sono state valutate le performance, nei confronti di sieri suini, di un test FPA (Fluorescence Polarization Assay commerciale sviluppato per la ricerca di anticorpi anti-Brucella in sieri bovini; la specificità e la sensibilità ottenute sono entrambe del 100% al valore di cut-off di 99.5 (mP. Questi risultati suggeriscono che la combinazione di c-ELISA, i-ELISA e FPA può essere utilizzata per migliorare la diagnosi di brucellosi suina.

  8. O negro no cinema brasileiro: O período silencioso

    Directory of Open Access Journals (Sweden)

    Noel dos Santos Carvalho

    2003-01-01

    Full Text Available Este artigo trata da participação do negro no cinema brasileiro no período de 1898 até os anos 1920. Seu objetivo é: 1 contextualizar o cinema no Brasil em relação à problemática vivida pela população negra no período pós-abolicionista; 2 descrever, ainda que sucintamente, os filmes que trazem representações sobre o negro brasileiro, 3 discutir as representações do negro em cinco filmes.

  9. Planeamiento estratégico del espárrago en el Perú

    OpenAIRE

    Muñoz Díaz, Jorge Luis; Solórzano Ramos, Javier Enrique; Soldevilla Canales, Roger Antonio

    2013-01-01

    xxi, 123 h. : il. ; 30 cm. El Perú es el primer exportador de Espárrago del Mundo, se comercializa principalmente al mercado americano y europeo por su alta calidad; la variedad de microclimas permite que esta hortaliza se coseche durante todo el año, lo que constituye que el Perú sea considerado un país con ventajas de abastecimiento, respecto de otros países. Para alcanzar la Visión al 2023, se deben lograr los siguientes objetivos de largo plazo: (a) Las exportaciones per...

  10. Debtoid : Una aplicació de gestió de deutes per a Android

    OpenAIRE

    Bueno Moreno, Víctor

    2015-01-01

    Aquesta memòria recull l'elaboració d'una aplicació per a dispositius mòbils amb sistema operatiu Android. L'aplicació Debtoid neix com a resultat de les inquietuds personals envers el sistema operatiu Android i la possibilitat de crear una aplicació per registrar pagaments a mitges. L'objectiu final de l'aplicació consisteix en un sistema que permet al dispositiu mòbil registrar els deutes i pagaments introduïts per l'usuari, amb la possibilitat d'enviar a altres usuaris notificacions mitjan...

  11. Mapping crime levels and court efficiency per magisterial district in South Africa.

    CSIR Research Space (South Africa)

    Schmitz, Peter MU

    2002-12-01

    Full Text Available the South African Police Service (SAPS) were reclassified into the six major categories used by DoJ, and the crime levels per magisterial district were calculated, imported into a Geographic Information System (GIS) and mapped per magisterial district...

  12. Mapping crime levels and court efficiency per magisterial district in South Africa

    CSIR Research Space (South Africa)

    Schmitz, Peter MU

    2002-12-01

    Full Text Available the South African Police Service (SAPS) were reclassified into the six major categories used by DoJ, and the crime levels per magisterial district were calculated, imported into a Geographic Information System (GIS) and mapped per magisterial district...

  13. Food-anticipatory activity and liver per1-luc activity in diabetic transgenic rats

    Science.gov (United States)

    Davidson, Alec J.; Stokkan, Karl-Arne; Yamazaki, Shin; Menaker, Michael

    2002-01-01

    The mammalian Per1 gene is an important component of the core cellular clock mechanism responsible for circadian rhythms. The rodent liver and other tissues rhythmically express Per1 in vitro but typically damp out within a few cycles. In the liver, the peak of this rhythm occurs in the late subjective night in an ad lib-fed rat, but will show a large phase advance in response to restricted availability of food during the day. The relationship between this shift in the liver clock and food-anticipatory activity (FAA), the circadian behavior entrained by daily feeding, is currently unknown. Insulin is released during feeding in mammals and could serve as an entraining signal to the liver. To test the role of insulin in the shift in liver Per1 expression and the generation of FAA, per-luciferase transgenic rats were made diabetic with a single injection of streptozotocine. Following 1 week of restricted feeding and locomotor activity monitoring, liver was collected for per-luc recording. In two separate experiments, FAA emerged and liver Per1 phase-shifted in response to daytime 8-h food restriction. The results rule out insulin as a necessary component of this system.

  14. Evaluating droplet digital PCR for the quantification of human genomic DNA: converting copies per nanoliter to nanograms nuclear DNA per microliter.

    Science.gov (United States)

    Duewer, David L; Kline, Margaret C; Romsos, Erica L; Toman, Blaza

    2018-05-01

    The highly multiplexed polymerase chain reaction (PCR) assays used for forensic human identification perform best when used with an accurately determined quantity of input DNA. To help ensure the reliable performance of these assays, we are developing a certified reference material (CRM) for calibrating human genomic DNA working standards. To enable sharing information over time and place, CRMs must provide accurate and stable values that are metrologically traceable to a common reference. We have shown that droplet digital PCR (ddPCR) limiting dilution end-point measurements of the concentration of DNA copies per volume of sample can be traceably linked to the International System of Units (SI). Unlike values assigned using conventional relationships between ultraviolet absorbance and DNA mass concentration, entity-based ddPCR measurements are expected to be stable over time. However, the forensic community expects DNA quantity to be stated in terms of mass concentration rather than entity concentration. The transformation can be accomplished given SI-traceable values and uncertainties for the number of nucleotide bases per human haploid genome equivalent (HHGE) and the average molar mass of a nucleotide monomer in the DNA polymer. This report presents the considerations required to establish the metrological traceability of ddPCR-based mass concentration estimates of human nuclear DNA. Graphical abstract The roots of metrological traceability for human nuclear DNA mass concentration results. Values for the factors in blue must be established experimentally. Values for the factors in red have been established from authoritative source materials. HHGE stands for "haploid human genome equivalent"; there are two HHGE per diploid human genome.

  15. Communally Nesting Migratory Birds Create Ecological Hot-Spots in Tropical Australia.

    Directory of Open Access Journals (Sweden)

    Daniel J D Natusch

    Full Text Available Large numbers of metallic starlings (Aplonis metallica migrate annually from New Guinea to the rainforests of tropical Australia, where they nest communally in single emergent trees (up to 1,000 birds. These aggregations create dense and species-rich faunal "hot-spots", attracting a diverse assemblage of local consumers that utilise this seasonal resource. The starlings nested primarily in poison-dart trees (Antiaris toxicaria near the rainforest-woodland boundary. Surveys underneath these colonies revealed that bird-derived nutrients massively increased densities of soil invertebrates and mammals (primarily wild pigs beneath trees, year-round. Flying invertebrates, nocturnal birds, reptiles, and amphibians congregated beneath the trees when starlings were nesting (the wet-season. Diurnal birds (primarily cockatoos and bush turkeys aggregated beneath the trees during the dry-season to utilise residual nutrients when the starlings were not nesting. The abundance of several taxa was considerably higher (to > 1000-fold under colony trees than under nearby trees. The system strikingly resembles utilisation of bird nesting colonies by predators in other parts of the world but this spectacular system has never been described, emphasizing the continuing need for detailed natural-history studies in tropical Australia.

  16. Communally Nesting Migratory Birds Create Ecological Hot-Spots in Tropical Australia.

    Science.gov (United States)

    Natusch, Daniel J D; Lyons, Jessica A; Brown, Gregory; Shine, Richard

    2016-01-01

    Large numbers of metallic starlings (Aplonis metallica) migrate annually from New Guinea to the rainforests of tropical Australia, where they nest communally in single emergent trees (up to 1,000 birds). These aggregations create dense and species-rich faunal "hot-spots", attracting a diverse assemblage of local consumers that utilise this seasonal resource. The starlings nested primarily in poison-dart trees (Antiaris toxicaria) near the rainforest-woodland boundary. Surveys underneath these colonies revealed that bird-derived nutrients massively increased densities of soil invertebrates and mammals (primarily wild pigs) beneath trees, year-round. Flying invertebrates, nocturnal birds, reptiles, and amphibians congregated beneath the trees when starlings were nesting (the wet-season). Diurnal birds (primarily cockatoos and bush turkeys) aggregated beneath the trees during the dry-season to utilise residual nutrients when the starlings were not nesting. The abundance of several taxa was considerably higher (to > 1000-fold) under colony trees than under nearby trees. The system strikingly resembles utilisation of bird nesting colonies by predators in other parts of the world but this spectacular system has never been described, emphasizing the continuing need for detailed natural-history studies in tropical Australia.

  17. Velloziaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Velloziaceae está representada en el Perú solamente por un género, Barbaceniopsis, y una especie arbustiva (Brako & Zarucchi, 1993. En este trabajo reconocemos el endemismo de esta especie, la cual se distribuye en matorrales de valles interandinos de la región Mesoandina, entre los 2100 y 2900 m de altitud. No está representada dentro de áreas naturales protegidas.

  18. The Experience in Personal Social Systems Questionnaire (EXIS.pers): Development and Psychometric Properties.

    Science.gov (United States)

    Hunger, Christina; Bornhäuser, Annette; Link, Leoni; Geigges, Julian; Voss, Andreas; Weinhold, Jan; Schweitzer, Jochen

    2017-03-01

    This study presents the theoretical background, development, and psychometric properties of the German and English versions of the Experience in Personal Social Systems Questionnaire (EXIS.pers). It assesses how the members of a personal social system experience their situation within that system. It is designed as a research tool for interventions in which only one member of the system participates (e.g., Family Constellation Seminars). The EXIS.pers was created to measure change on the individual level relating to one's own important personal social system. In Study 1, we used exploratory factor analysis (EFA) for latent variable identification of the original German EXIS.pers (n = 179). In Studies 2 and 3, we used confirmatory factor analysis (CFA) to examine the dimensionality of the German (n = 634) and English (n = 310) EXIS.pers. Internal consistencies and cross-cultural structural equivalence were assessed. EFA indicated that a four-factor model provided best fit for the German EXIS.pers. For both the German and English EXIS.pers, CFA provided the best fit for a five-factor bi-level model that included a general factor (Experience In Personal Social Systems) and four dimensions (Belonging, Autonomy, Accord, Confidence). Good internal consistencies, external associations, and cross-cultural structural equivalence were demonstrated. This study provides first evidence for the German and English EXIS.pers as an economical and reliable measure of an individual's experience within his or her personal social systems. © 2016 Family Process Institute.

  19. KAJIAN MANAJEMEN PRODUKSI PEMBERITAAN PSO BIDANG PERS OLEH LKBN ANTARA

    Directory of Open Access Journals (Sweden)

    Primayanti Primayanti

    2015-05-01

    Full Text Available Based on Government Regulation No. 40 Year 2007 on Perum ANTARA do fund public services (public service obligation / PSO in the field of government information. ANTARA position is also very strategic in the middle of the fight-laden media industry interests. Also, the need to get in the news media with the retail product line strategy while maintaining the main products for the media.Results of this study showed that the press area of public service obligations (PSO-Field Press includes a number of products and services that news text, photo news, and TV news. In line with government policies and programs, also set a number of themes that frame the products and services fields PSO Press.PSO and Field Releases can be interpreted as the government's efforts to maintain control and domination of the media life, given the strategic function of political economy of media. A contradiction was born. On the one hand, the government wants to adopt the principles of the liberal press, on the other hand maintain government policies in the media sector as opposed to the spirit of libertarianism. Berdasarkan Peraturan Pemerintah Nomor 40 Tahun 2007 tentang Perum LKBN ANTARA dilakukan dana pelayanan umum (public service obligation/PSO di bidang informasi dari pemerintah. Posisi LKBN ANTARA juga sangat strategis di tengah pertarungan industri media yang sarat kepentingan. Juga, perlunya kantor berita masuk media ritel dengan strategi lini produk dengan tetap mempertahankan produk utama untuk media.Hasil penelitian ini menujukkan bahwa kewajiban pelayanan umum bidang pers (PSO-Bidang Pers tersebut mencakup sejumlah produk dan layanan yaitu berita teks, berita foto, dan berita TV. Agar sejalan dengan program dan kebijakan pemerintah, ditetapkan pula sejumlah tema yang membingkai produk dan layanan PSO Bidang Pers.PSO Bidang Pers dapat dimaknai sebagai upaya pemerintah yang ingin mempertahankan kontrol dan dominasinya terhadap kehidupan media, mengingat begitu

  20. LA FORMAZIONE DEGLI INSEGNANTI PER UNA EDUCAZIONE PLURILINGUE E INTERCULTURALE

    Directory of Open Access Journals (Sweden)

    Edoardo Lugarini

    2012-07-01

    Full Text Available Dalla la Guida per lo sviluppo e l’attuazione di curricoli per una educazione plurilingue e interculturale del Consiglio d’Europa è possibile trarre una serie di indicazioni per disegnare un profilo professionale e, di conseguenza, una serie di indicazioni per la formazione iniziale e in servizio dell’insegnate di lingua (L1, L2, LS. In questo intervento si suggeriscono, senza alcuna pretesa di esaustività, degli indicatori relativi alle competenze professionali che l’insegnante dovrebbe possedere per poter svolgere la sua attività nella scuola italiana di oggi in considerazione dei bisogni linguistici delle nuove generazioni e degli obiettivi linguistici proposti dal Consiglio d’Europa nell’ambito delle politiche educative orientate a favorire la mobilità, una più efficace comunicazione internazionale, il rispetto dell’identità e della diversità delle culture, a sviluppare l’educazione alla cittadinanza democratica ed europea. Dalle riflessioni condotte emerge la necessità di una formazione disciplinare e didattica articolata e complessa che renda l’insegnante “professionista riflessivo” e “ricercatore sperimentale”TRAINING TEACHERS FOR MULTILINGUISTIC, INTERCULTURAL EDUCATIONFrom the Council of Europe’s Guide for the development and implementation of curricula for multilingual and intercultural education, it is possible to draw a series of explicit or implicit characteristics for teachers, and consequently, a series of indications for initial and in-service language (L1, L2, FL teacher training. This paper offers a brief view of the professional competences teachers should possess in order to carry out their roles in Italian schools considering the linguistic needs of the young generations and the language objectives set out by the Council of Europe regarding education policies that promote mobility, more effective International communication and respect for cultural identity and diversity, in an effort to

  1. La imagen en el Perú ilustrado. (Lima, 1887-1892

    Directory of Open Access Journals (Sweden)

    2003-01-01

    Full Text Available El Perú Ilustrado est la première revue illustrée publiée au Pérou. Comme l’ensemble de la presse péruvienne du XIXe siècle, cet hebdomadaire n’a pas fait l’objet d’études monographiques alors qu’il présente un matériel iconographique de première importance. Notre analyse s’intéresse d’abord au frontispice de la revue qui revêt un caractère emblématique, opposant un idéal de progrès à un pays jugé archaïque. Viennent ensuite les portraits qui valorisent tout particulièrement le modèle du self made man. Le Pérou du Nord au Sud défile dans les pages du journal, représentation d’un monde sur le chemin de la modernité. Les légendes et les commentaires qui accompagnent les gravures révèlent les présupposés idéologiques des rédacteurs, repoussant en dernière page la représentation des types populaires. El Perú Ilustrado s’avère ainsi une arme à double tranchant, expression des ambiguïtés du discours progressiste de la fin du XIXe siècle. L’IMAGE DANS EL PERÚ ILUSTRADO (LIMA, 1887-1892. El Perú Ilustrado fue la primera revista ilustrada que se publicó en el Perú. Como el conjunto de la prensa peruana del siglo XIX, ese semanario no ha sido objeto de estudios monográficos aunque presenta un material iconográfico de primera importancia. Nuestro análisis se interesa primero por la portada de la revista que tiene un carácter emblemático, pues opone un ideal de progreso a un país considerado arcaíco. Luego vienen los retratos que valoran en especial el modelo del self made man. Va desfilando el Perú de norte a sur, como representación de un mundo encaminado hacia la modernidad. Las leyendas y los comentarios que acompañan los grabados delatan los presupuestos ideológicos del cuerpo de redactores que postergan hasta la última plana la representación de los tipos populares. El Perú Ilustrado resulta así un arma de doble filo, expresión de las ambigüedades del discurso progresista de

  2. Desenvolvimentismo e política econômica: um cotejo entre Vargas e Perón Developmentalism and economic policy: a comparison between Vargas and Perón

    Directory of Open Access Journals (Sweden)

    Pedro Cezar Dutra Fonseca

    2012-12-01

    Full Text Available O artigo compara a política econômica de duas experiências desenvolvimentistas na América Latina: o primeiro período governamental de Vargas (Brasil, 1930-1945 e Perón (Argentina, 1946-1955. Embora aceite a semelhança entre ambas, comumente mais enfatizada pela literatura, procura mostrar certas diferenças entre elas em matéria de natureza econômica. Defende que, enquanto Vargas centravase em medidas para mudar a estrutura econômica do país, com ênfase à industrialização, Perón deu maior prioridade à redistribuição de renda do que a mudanças no modelo econômico, o qual já vinha sendo implementado na Argentina antes de seu governo.This paper compares economic policy characteristics of two developmentalist experiences in Latin America: the first Vargas administration (Brazil, 1930-1945 and the Perón administration (Argentina, 1946-1955. Although certain similarities exist between them (which are usually stressed in the literature, this article seeks to reveal some differences that are economic in nature. While Vargas focused on measures that would change the country's economic structure and with an emphasis on industrialization, Perón prioritized income distribution more than any changes to the economic model that had been implemented before his administration took office.

  3. Genetic diversity of Annona senegalensis Pers. populations as ...

    African Journals Online (AJOL)

    Annona senegalensis Pers. is one of the wild fruit tree for domestication in southern Africa. An assessment of the genetic diversity in A. senegalensis would assist in planning for future germplasm collection, conservation and fruit domestication programmes. During 2004 to 2006 nine populations were collected from different ...

  4. Role of the circadian clock gene Per2 in adaptation to cold temperature.

    Science.gov (United States)

    Chappuis, Sylvie; Ripperger, Jürgen Alexander; Schnell, Anna; Rando, Gianpaolo; Jud, Corinne; Wahli, Walter; Albrecht, Urs

    2013-01-01

    Adaptive thermogenesis allows mammals to resist to cold. For instance, in brown adipose tissue (BAT) the facultative uncoupling of the proton gradient from ATP synthesis in mitochondria is used to generate systemic heat. However, this system necessitates an increase of the Uncoupling protein 1 (Ucp1) and its activation by free fatty acids. Here we show that mice without functional Period2 (Per2) were cold sensitive because their adaptive thermogenesis system was less efficient. Upon cold-exposure, Heat shock factor 1 (HSF1) induced Per2 in the BAT. Subsequently, PER2 as a co-activator of PPARα increased expression of Ucp1. PER2 also increased Fatty acid binding protein 3 (Fabp3), a protein important to transport free fatty acids from the plasma to mitochondria to activate UCP1. Hence, in BAT PER2 is important for the coordination of the molecular response of mice exposed to cold by synchronizing UCP1 expression and its activation.

  5. Energy consumptions per sector; Les consommations d'energie par secteur

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This document presents the energy consumption data of France per energy type and sector of use in the form of tables and graphics for the last decade and sometimes before: 1 - residential and tertiary sector: energy consumption per energy source, energy consumption per use (coal, heavy and domestic fuels, natural gas, LPG (butane, propane), electricity), comparison of the share of each energy source between 1973 and 2003, 20 years of space heating data in main dwellings (1982-2002), district heating networks from 1987 to 1997; 2 - transportation sector: fuel consumption of individual cars in France (1990-2003, 1990-2002, 1990-2001, 1987-1999), some indicators about the energy consumption in transports in France (2000-2001); 3 - industry sector: consumption of fuel substitutes in the cement industry in 2001, importance and limitations. (J.S.)

  6. Castelli di carta. La piega per la costruzione di superfici articolate

    Directory of Open Access Journals (Sweden)

    Andrea Casale

    2012-06-01

    Full Text Available L’antica arte del piegare la carta, l’Origami, sta vivendo un rinnovato interesse che coinvolge molti aspetti della ricerca.  Con il termine origami, si intende lo studio del modo di piegare il foglio di carta per imporgli una specifica forma.  La superficie tassellata per mezzo di specifiche pieghe, si propone come un nuovo soggetto di studio: la superficie piegata articolata. La forma congiunta al movimento, assume un particolare interesse nella contemporanea ricerca geometrica e architettonica. Il panorama contemporaneo, propone opere di architettura “responsiva”, capaci di modificare le proprie caratteristiche per adeguarsi a nuove condizioni. La superficie piegata articolata sembra particolarmente adatta a descrivere questo modo d’intendere l’architettura, reagendo a diverse volontà e di conseguenza modificando la propria conformazione attraverso un attento controllo progettuale della forma.

  7. O período toxêmico da esquistossomose

    Directory of Open Access Journals (Sweden)

    J. Leocádio

    1969-06-01

    Full Text Available O A. apresenta seis casos de pacientes observados durante o período toxêmico da esquistosomose mansônica. Dêstes, um foi de mulher cuja sintomatologia datava de um ano. Concebeu e deu à luz durante a enfermidade. Apresentava sinais de fibrose hepática quando do primeiro exame, ainda na vigência de sintomas do período agudo da enfermidade. Todos êstes pacientes apresentavam febre, dores abdominais, hepatoesplenomegalia e outras manifestações que têm sido descritas neste período da parasitose. Como notas dominantes no hemograma, leucocitose com eosinofilia, como ocorre nas infecções por helmintos com ciclo textrino, e anemia. Esta, nem todos apresentavam. Além de alterações do equilíbrio proteico e de resultados da exploração funcional do fígado, o A. chamou a atenção para a hípoglicemia e hipocolesterolemia encontradas em alguns dos observados. Foi digno de registro, também, a positividade tardia da intradermorreação para diagnóstico da esquistosomose. Todos os pacientes foram submetidos a tratamento antimonial, com bom resultado. Como reação colateral devemos mencionar a exacerbação da febre forçando, por vêzes à interrupção do mesmo. O A. faz referências a outros recursos terapêuticos empregados no Oriente: o F30.066, um nitrofurano de uso oral, e as sementes de Cucurbita moshata. Sugere a investigação em animais e no homem com sementes de abóbora outrora empregadas como tenifugo

  8. Ka-Band, Multi-Gigabit-Per-Second Transceiver

    Science.gov (United States)

    Simons, Rainee N.; Wintucky, Edwin G.; Smith, Francis J.; Harris, Johnny M.; Landon, David G.; Haddadin, Osama S.; McIntire, William K.; Sun, June Y.

    2011-01-01

    A document discusses a multi-Gigabit-per-second, Ka-band transceiver with a software-defined modem (SDM) capable of digitally encoding/decoding data and compensating for linear and nonlinear distortions in the end-to-end system, including the traveling-wave tube amplifier (TWTA). This innovation can increase data rates of space-to-ground communication links, and has potential application to NASA s future spacebased Earth observation system. The SDM incorporates an extended version of the industry-standard DVB-S2, and LDPC rate 9/10 FEC codec. The SDM supports a suite of waveforms, including QPSK, 8-PSK, 16-APSK, 32- APSK, 64-APSK, and 128-QAM. The Ka-band and TWTA deliver an output power on the order of 200 W with efficiency greater than 60%, and a passband of at least 3 GHz. The modem and the TWTA together enable a data rate of 20 Gbps with a low bit error rate (BER). The payload data rates for spacecraft in NASA s integrated space communications network can be increased by an order of magnitude (>10 ) over current state-of-practice. This innovation enhances the data rate by using bandwidth-efficient modulation techniques, which transmit a higher number of bits per Hertz of bandwidth than the currently used quadrature phase shift keying (QPSK) waveforms.

  9. Facility Management personalizzato per realtà complesse

    Directory of Open Access Journals (Sweden)

    Autodesk Italia Autodesk Italia

    2007-04-01

    Full Text Available Il mercato dei servizi oggi è caratterizzato da una crescente complessità; in particolare il mondo dell’Information & Communication Technology si trova di fronte a un processo di vera e propria trasformazione del concetto di servizio: dalla semplice manutenzione hardware e software si è passati alla presa in carico di attività che un tempo erano affidate a fornitori diversi. Le aziende di global services necessitano quindi di informazioni aggiornate e complete, per poter rispondere tempestivamente e con efficacia alle richieste delle aziende. In qualità di struttura istituzionale di supporto all’attività del Presidente del Consiglio, la Presidenza del Consiglio dei Ministri aveva la necessità di realizzare un sistema informativo che supportasse i propri fornitori nell’erogazione dei servizi, in particolare nell’espletamento del contratto siglato per la manutenzione degli edifici e nell’ottimizzazione della manutenzione di questi servizi. Questi ultimi includono manutenzioni di carattere ordinario e straordinario, che vanno dalla sostituzione di una lampadina, alla tinteggiatura, al ripristino di un affresco o di un fregio artistico, alla manutenzione del verde sia all’esterno che all’interno degli edifici della Presidenza del Consiglio.

  10. La riscoperta della stereoscopia per la rappresentazione dello spazio architettonico

    Directory of Open Access Journals (Sweden)

    Simone Garagnani

    2011-06-01

    Full Text Available Il progressivo sviluppo dei metodi della rappresentazione grafica nel corso della storia è stato possibile in virtù della scoperta di strumenti e tecniche appartenenti al loro tempo: questo continuo progresso delle modalità di “raccontare” l’architettura è tuttora in corso di evoluzione, costituendo il fondamento di ogni strategia informativa e di comunicazione del progetto. Il sempre più pervasivo trattamento digitale dell’informazione, sia essa grafica che testuale, ha condotto ad una progressiva riscoperta di approcci tradizionali nella descrizione dello spazio costruito, declinandoli alle nuove tecnologie informatiche per amplificarne possibilità e valenze. È il caso della stereoscopia, diffuso metodo ottocentesco adottato in fotografia per rendere spaziale la percezione dell’immagine sfruttando la visione binoculare; oggi i modelli tridimensionali e le immagini digitali catturate da apposite fotocamere rendono l’approccio stereoscopico di immediato utilizzo anche per i profani della rappresentazione, semplificando e rendendo trasparenti i concetti di geometria proiettiva alla base del metodo. Questo contributo intende indagare le funzionalità, i vantaggi e le criticità della tecnologia stereoscopica immersiva nella moderna comunicazione del progetto d’architettura.

  11. 47 CFR 64.1510 - Billing and collection of pay-per-call and similar service charges.

    Science.gov (United States)

    2010-10-01

    ... Pay-Per-Call and Other Information Services § 64.1510 Billing and collection of pay-per-call and... pay-per-call services and offering billing and collection services to such provider shall: (1) Ensure... 47 Telecommunication 3 2010-10-01 2010-10-01 false Billing and collection of pay-per-call and...

  12. Cristine de Pizan e le emozioni per la Cità des Dames

    Directory of Open Access Journals (Sweden)

    Angela Giallongo

    2011-06-01

    Full Text Available L’interesse storico per le emozioni spinge ad interrogarsi sul loro ruolo nelle utopie femminili alla fine del medioevo. Una fonte centrale su questo tema è l’opera illustrata la Cité des Dames (1405 di C. de Pizan (1365-1430. Gli studi di B.H. Rosenwein, W. Reddie e K.Oatley forniscono categorie interpretative psico-sociali (comunità emotive e regime emotivo utili per connettere l’idea di utopia, valori emotivi e rapporti interpersonali fra i sessi. La problematicizzazione, suggerita da Rosenwein, della comunità immaginata come comunità emotiva aiuta a identificare i modi di sentire rifiutati e quelli privilegiati per l’espressione del senso di sé e per la costruzione della città ideale, offerta alle donne di tutte le classi sociali.In conclusione, l’analisi qualitativa dell’opera della de Pizan focalizza l’uso formativo delle immagini mitiche, l’esperienza dell’autrice, contestualizzata nel periodo, e i significati culturali attribuiti alle “emozioni”.

  13. Il MUDE Piemonte - modello unico digitale per l’edilizia: un progetto organizzativo

    Directory of Open Access Journals (Sweden)

    Livio Mandrile

    2012-12-01

    Full Text Available Le tecnologie dell’informazione e della comunicazione consentono di affrontare la reingegnerizzazione dei processi amministrativi attraverso servizi informatici definiti “di cooperazione applicativa”, aprendo nuove prospettive per semplificare il rapporto fra cittadino e Pubbliche Amministrazioni e agevolare lo scambio di documenti e informazioni. Il MUDE Piemonte – modello unico digitale per l’edilizia - è un sistema informativo realizzato attraverso la collaborazione di tutti i livelli di governo del territorio regionale, che crea un archivio digitale delle pratiche edilizie presentate allo Sportello per l’Edilizia, utilizzando il mezzo telematico per l’interazione fra professionista e Pubblica Amministrazione e l’interscambio informativo fra le banche dati amministrative. Il MUDE Piemonte è un sistema che realizza un ambiente operativo di fruizione / aggiornamento della base di dati territoriali ed amministrativi ad uso di più soggetti ed enti e in costante evoluzione in ragione dell’apporto progettuale offerto da tutti gli attori coinvolti nei procedimenti autorizzativi edilizi.

  14. Parental GCA testing: how many crosses per parent?

    Science.gov (United States)

    G.R. Johnson

    1998-01-01

    The impact of increasing the number of crosses per parent (k) on the efficiency of roguing seed orchards (backwards selection, i.e., reselection of parents) was examined by using Monte Carlo simulation. Efficiencies were examined in light of advanced-generation Douglas-fir (Pseudotsuga menziesii (Mirb.) Franco) tree improvement programs where...

  15. Making It Personal: Per Capita Carbon Allowances

    DEFF Research Database (Denmark)

    Fawcett, Tina; Hvelplund, Frede; Meyer, Niels I

    2009-01-01

    The Chapter highligts the importance of introducing new, efficient schemes for mitigation of global warming. One such scheme is Personal Carbon Allowances (PCA), whereby individuals are allotted a tradable ration of CO2 emission per year.This chapter reviews the fundamentals of PCA and analyzes its...... merits and problems. The United Kingdom and Denmark have been chosen as case studies because the energy situation and the institutional setup are quite different between the two countries....

  16. Urban movements and disempowerment in Perú and Venezuela Movimientos urbanos y desempoderamiento en Perú y Venezuela

    Directory of Open Access Journals (Sweden)

    Daniel H. LEVINE

    2010-11-01

    Full Text Available This paper addresses a core puzzle: why is continued citizen mobilization accompanied by growing disempowerment of those same citizens? Why do movements fail, leaders burn out and members disperse, and what are the implications of this organizational failure for demo¬cratic representation? Our consideration of the issues is rooted in a close examination of urban movements, mobilization, empowerment and disempowerment in the recent experience of Venezuela and Perú. The puzzle that concerns us is of course not limited to these two countries: it is common to all the Andean republics, and in different ways, to much recent experience of urban mobilization in Latin America and beyond. After a brief account of urban citizen move¬ments and politics in our two cases, we outline general reflections on the nature of empowerment and disempowerment, on the peculiar combination of strengths and weaknesses that mark many contemporary movements. A close examination of types of movements and their links with poli¬tical parties and protest follows. The character of city life is important here. We close with analysis of recent waves of urban mobilization in Perú (that sparked the ouster of president Alberto Fujimori and in Venezuela (both for and against president Hugo Chávez Frías, and with reflections on the likely future of empowerment and disempowerment for urban citizens and the implications of this perspective for democratic representationEste artículo plantea un puzzle principal: ¿por qué la movilización ciudadana continuada viene acompañada de un crecimiento del desempoderamiento de estos mismos ciudadanos? ¿Por qué los movimientos fracasan, los líderes se desgastan y los miembros se dispersan, y cuáles son las implicaciones del fracaso organizativo para la representación democrática? Nuestra consideración del asunto encuentra sus raíces en un profundo análisis de los movimientos urbanos, de la movilización, del empoderamiento y del

  17. Vasks: Cantabile per archi, Paul Mägi / Bernhard Uske

    Index Scriptorium Estoniae

    Uske, Bernhard

    1994-01-01

    Uuest heliplaadist "Vasks: Cantabile per archi; Botschaft: Musica Dolorosa, Sinfonie für Streicher (Stimmen). Latvijas Nicionalais Simfoniskais Orkestris, Latvijas Filharmonijas Kamerorkestris. Pauls Megi [Paul Mägi]", Tovijs Lifsics. Wergo CD 6220-2

  18. Exploring the Landscape of Diazabicyclooctane (DBO) Inhibition: Avibactam Inactivation of PER-2 β-Lactamase.

    Science.gov (United States)

    Ruggiero, Melina; Papp-Wallace, Krisztina M; Taracila, Magdalena A; Mojica, Maria F; Bethel, Christopher R; Rudin, Susan D; Zeiser, Elise T; Gutkind, Gabriel; Bonomo, Robert A; Power, Pablo

    2017-06-01

    PER β-lactamases are an emerging family of extended-spectrum β-lactamases (ESBL) found in Gram-negative bacteria. PER β-lactamases are unique among class A enzymes as they possess an inverted omega (Ω) loop and extended B3 β-strand. These singular structural features are hypothesized to contribute to their hydrolytic profile against oxyimino-cephalosporins (e.g., cefotaxime and ceftazidime). Here, we tested the ability of avibactam (AVI), a novel non-β-lactam β-lactamase inhibitor to inactivate PER-2. Interestingly, the PER-2 inhibition constants (i.e., k 2 / K = 2 × 10 3 ± 0.1 × 10 3 M -1 s -1 , where k 2 is the rate constant for acylation (carbamylation) and K is the equilibrium constant) that were obtained when AVI was tested were reminiscent of values observed testing the inhibition by AVI of class C and D β-lactamases (i.e., k 2 / K range of ≈10 3 M -1 s -1 ) and not class A β-lactamases (i.e., k 2 / K range, 10 4 to 10 5 M -1 s -1 ). Once AVI was bound, a stable complex with PER-2 was observed via mass spectrometry (e.g., 31,389 ± 3 atomic mass units [amu] → 31,604 ± 3 amu for 24 h). Molecular modeling of PER-2 with AVI showed that the carbonyl of AVI was located in the oxyanion hole of the β-lactamase and that the sulfate of AVI formed interactions with the β-lactam carboxylate binding site of the PER-2 β-lactamase (R220 and T237). However, hydrophobic patches near the PER-2 active site (by Ser70 and B3-B4 β-strands) were observed and may affect the binding of necessary catalytic water molecules, thus slowing acylation ( k 2 / K ) of AVI onto PER-2. Similar electrostatics and hydrophobicity of the active site were also observed between OXA-48 and PER-2, while CTX-M-15 was more hydrophilic. To demonstrate the ability of AVI to overcome the enhanced cephalosporinase activity of PER-2 β-lactamase, we tested different β-lactam-AVI combinations. By lowering MICs to ≤2 mg/liter, the ceftaroline-AVI combination could represent a favorable

  19. Melatonin Entrains PER2::LUC Bioluminescence Circadian Rhythm in the Mouse Cornea

    Science.gov (United States)

    Baba, Kenkichi; Davidson, Alec J.; Tosini, Gianluca

    2015-01-01

    Purpose Previous studies have reported the presence of a circadian rhythm in PERIOD2::LUCIFERASE (PER2::LUC) bioluminescence in mouse photoreceptors, retina, RPE, and cornea. Melatonin (MLT) modulates many physiological functions in the eye and it is believed to be one of the key circadian signals within the eye. The aim of the present study was to investigate the regulation of the PER2::LUC circadian rhythm in mouse cornea and to determine the role played by MLT. Methods Corneas were obtained from PER2::LUC mice and cultured to measure bioluminescence rhythmicity in isolated tissue using a Lumicycle or CCD camera. To determine the time-dependent resetting of the corneal circadian clocks in response to MLT or IIK7 (a melatonin type 2 receptor, MT2, agonist) was added to the cultured corneas at different times of the day. We also defined the location of the MT2 receptor within different corneal layers using immunohistochemistry. Results A long-lasting bioluminescence rhythm was recorded from cultured PER2::LUC cornea and PER2::LUC signal was localized to the corneal epithelium and endothelium. MLT administration in the early night delayed the cornea rhythm, whereas administration of MLT at late night to early morning advanced the cornea rhythm. Treatment with IIK7 mimicked the MLT phase-shifting effect. Consistent with these results, MT2 immunoreactivity was localized to the corneal epithelium and endothelium. Conclusions Our work demonstrates that MLT entrains the PER2::LUC bioluminescence rhythm in the cornea. Our data indicate that the cornea may represent a model to study the molecular mechanisms by which MLT affects the circadian clock. PMID:26207312

  20. The Potential of Tephrosia and Vernonia as Anthelmintics Against Gastrointestinal in Goats

    International Nuclear Information System (INIS)

    Simba, D.N

    2002-01-01

    Eighteen dual purpose goats were used to evaluate the effects of feeding Calliandra caryothyrsus leaf meat at different patterns as a supplement to Rhodes grass hay on intake, nitrogen utilization and milk yield. A basal diet of low quality Rhodes grass hay (fed 90% and libitum) and 100 g maize germ were offered to the goats over a 60-day experimental period. The treatments were:- (TI) 100 g day - 1 calliandra for 60 days; (T2) 200 g day - 1 calliandra for 30 days followed by another 30 days where 200 g or 0 g day - 1 calliandra alternated every 5 days; and (T3) 200 g or 0 day - 1 calliandra alternated every 5 days for 60 days. Total dry matter intake (TDM) was significantly (P - 1 for T1, T2 and T3 respectively. Milk yields had similar trends averaged 166.1, 231.8 and 20.1 g day - 1 for T1, T2 and T3 respectively. The utilization of nitrogen was also significantly (P<0.05) affected by the pattern of supplement feeding. It was concluded from the results that the overall animal response could be influenced by how limited quantity f supplement was fed

  1. Study of uranium - 20 Wt per cent plutonium-niobium alloys (1963)

    International Nuclear Information System (INIS)

    Abgrall, J.; Barthelemy, P.; Boucher, R.

    1963-01-01

    U-Pu-Nb alloys containing 20 wt per cent Pu and 10 - 20 - 30 - 40 - 50 or 60 wt per cent Nb have been studied principally to determine the feasibility of their use as fuel element. The fabrication, casting and homogenisation presented certain difficulties due specially to niobium. The transformation temperatures, thermal expansion coefficients and nature of phases have been determined by thermal analysis, dilatometry, micrography and X Rays diffraction. For similar compositions, U-Pu-Mo and U-Pu-Nb alloys have many common points concerning the presence of zeta phase (up to 40 wt per cent Nb), the coefficients of expansion, the good behaviour during thermal cycling and the good resistance to air oxidation in spite of zeta phase. In consequence, irradiation tests in EL 3 reactor (Saclay) will be carried out in the near future. (authors) [fr

  2. Nonlinear Effects of Remittances on Per Capita GDP Growth in Bangladesh

    Directory of Open Access Journals (Sweden)

    Gazi Mainul Hassan

    2017-07-01

    Full Text Available This paper examines the impact of inward remittances flows on per capita gross domestic product (GDP growth in Bangladesh during 1976–2012. We find that the growth effect of remittances is negative at first but becomes positive at a later stage, evidence of a non-linear relationship. Unproductive use of remittances was rampant in the beginning when they were received by migrant families, but better social and economic investments led to more productive utilization of remittances receipts at later periods. This suggests a U-shaped relationship between remittances and per capita GDP growth. Unlike what is suggested in the literature, that the effect of remittances is more pronounced in a less financially developed economy, our evidence does not show that the effect of remittances on per capita GDP growth in Bangladesh is conditional on the level of financial development.

  3. Costo anual per cápita en primer nivel de atención por género Cost per capita in outpatients by gender

    Directory of Open Access Journals (Sweden)

    Enrique Villarreal-Ríos

    2011-03-01

    Full Text Available El objetivo de este artículo es estimar el costo per cápita anual por género en primer nivel de atención. MÉTODOS: estudio de costo realizado en Unidades de Medicina Familiar en México. La información correspondió al año 2004 y el estudio se dividió en perfil de uso y costo de la atención. PERFIL DE USO DE LO SERVICIOS: se estudiaron los registros clínicos de 1,585 pacientes adscritos a unidades de medicina familiar. El perfil de uso se definió mediante el promedio y los motivos de atención por departamento, género y grupo de edad. COSTO DE LA ATENCIÓN: estimado en dólares estadounidenses incluyó costo unitario fijo (departamentalización ajustada por productividad, el costo unitario variable (técnica de microcosteo, costo unitario por departamento y motivo de atención, y costo unitario por departamento, quinquenio y género. La esperanza de vida fue de 73 años para los hombres y 78 para las mujeres. Se identificaron tres escenarios. RESULTADOS: el costo anual per capita es superior en la mujer US $73.24 (IC 95% $11.38 - $197.49 que en el hombre $ 53.11 (IC 95% 2.51 - 207.71. CONCLUSIÓN: en primer nivel de atención el costo per cápita en las mujeres es mayor que en los hombres, información valiosa en el proceso de planeación de los servicios de salud.The objective of this study is to identify the annual cost per capita by gender in first level of attention. It is a cost study in Family Physician Units in Mexico. The information corresponded to the year of 2004 and the study divided in the use profile and cost attention. USE PROFILE OF SERVICES: it was studied 1,585 clinical registries of patients, use profile defined by average and attention reasons by department, gender and age group. COST ATTENTION: considered in American dollars it included fixed unit cost (departmentalization adjusted by productivity, variable unit cost (micro cost technical, department unite cost by type attention, and department unit cost by age

  4. La (incumplida) promesa universitaria en el Perú

    OpenAIRE

    Cuenca, Ricardo; Reátegui, Luciana

    2016-01-01

    “El objetivo de este informe es mostrar qué sucedió con aquellas hipótesis de mediados de los años noventa mediante el análisis descriptivo de un conjunto de datos oficiales sobre la educación superior universitaria en el Perú.”—Introducción.

  5. 38 CFR 51.41 - Per diem for certain veterans based on service-connected disabilities.

    Science.gov (United States)

    2010-07-01

    ... facility, if the veteran: (1) Is in need of nursing home care for a VA adjudicated service-connected...' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) PER DIEM FOR NURSING HOME CARE OF VETERANS IN STATE HOMES Per Diem Payments § 51.41 Per diem for certain veterans based on service-connected disabilities...

  6. Loss of the clock protein PER2 shortens the erythrocyte life span in mice.

    Science.gov (United States)

    Sun, Qi; Zhao, Yue; Yang, Yunxia; Yang, Xiao; Li, Minghui; Xu, Xi; Wen, Dan; Wang, Junsong; Zhang, Jianfa

    2017-07-28

    Cell proliferation and release from the bone marrow have been demonstrated to be controlled by circadian rhythms in both humans and mice. However, it is unclear whether local circadian clocks in the bone marrow influence physiological functions and life span of erythrocytes. Here, we report that loss of the clock gene Per2 significantly decreased erythrocyte life span. Mice deficient in Per2 were more susceptible to acute stresses in the erythrocytes, becoming severely anemic upon phenylhydrazine, osmotic, and H 2 O 2 challenges. 1 H NMR-based metabolomics analysis revealed that the Per2 depletion causes significant changes in metabolic profiles of erythrocytes, including increased lactate and decreased ATP levels compared with wild-type mice. The lower ATP levels were associated with hyperfunction of Na + /K + -ATPase activity in Per2 -null erythrocytes, and inhibition of Na + /K + -ATPase activity by ouabain efficiently rescued ATP levels. Per2 -null mice displayed increased levels of Na + /K + -ATPase α1 (ATP1A1) in the erythrocyte membrane, and transfection of Per2 cDNA into the erythroleukemic cell line TF-1 inhibited Atp1a1 expression. Furthermore, we observed that PER2 regulates Atp1a1 transcription through interacting with trans-acting transcription factor 1 (SP1). Our findings reveal that Per2 function in the bone marrow is required for the regulation of life span in circulating erythrocytes. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

  7. Siete nuevos registros de Arctiini (Lepidoptera: Erebidae: Arctiinae para Perú

    Directory of Open Access Journals (Sweden)

    Juan Grados

    2013-12-01

    Full Text Available Se presenta siete nuevos registros de Arctiini (Erebidae: Lepidoptera para Perú. Algunas de las especies son raras en colecciones. Cada nuevo reporte pertenece a géneros diferentes, proporcionando para cada género las especies que ocurren en el Perú, basado en colecciones y las fuentes bibliográficas de las descripciones originales. Se da a conocer un nuevo sinónimo para Agyrtiola niepeltiGaede, 1926.

  8. Stoplight Grid: a color-coded visual system for per diem staff assignment.

    Science.gov (United States)

    Ernst, P

    1989-02-01

    What is the best way to appropriately assign per diem nursing personnel? The author describes a systematic approach to per diem staff assignment called the Stoplight Grid. The Stoplight Grid correlates staff skills and preferences with unit needs and integrates this data into a color-coded system for staff assignment.

  9. 100 per cent of renewable energy in France: a 'delusional' project?

    International Nuclear Information System (INIS)

    Danielo, Olivier; Thouverez, Pierre

    2016-01-01

    After having mentioned publications by researchers of the MIT and of the University of Stanford stating that the world could face its energetic needs with a 100 per cent WWS (wind water sun) system, the author comments reactions of one of these researchers about the French case: the 1384 TWh required could be distributed in 57 per cent of wind energy, 37 per cent of solar and 5 per cent of hydroelectricity. The author also evokes assessments performed by the ADEME on the potential of ground-based solar energy. According to the American study, 2.5 per cent of the French national surface would be enough for France to become entirely renewable. The author comments the differences between ADEME's and American assessments. He also discusses the issue of negative growth in relationship with these perspectives of development of renewable (and notably solar) energies. He proposes then an overview of various visions for the future, and outlines the difficulties for some so-called experts to change their approach

  10. Berberidaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Carmen Ulloa Ulloa

    2013-10-01

    Full Text Available La familia Berberidaceae es reconocida en el Perú con un género, Berberis, y 32 especies (Brako & Zarucchi, 1993, mayormente arbustos. Esta familia incluye 14 endemismos. La mayoría de estas especies endémicas ocupan la región Mesoandina, entre los 2000 y 4200 m de altitud. Dos de estos taxones endémicos están representados dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  11. CALiPER Exploratory Study. Recessed Troffer Lighting

    Energy Technology Data Exchange (ETDEWEB)

    Miller, N. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Royer, M. P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Poplawski, M. E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2013-03-01

    This CALiPER study examines the problems and benefits likely to be encountered with LED products intended to replace linear fluorescent lamps. LED dedicated troffers, replacement tubes, and non-tube retrofit kits were evaluated against fluorescent benchmark troffers in a simulated office space for photometric distribution, uniformity of light on the task surface, suitability of light output, flicker, dimming performance, color quality, power quality, safety and certification issues, ease of installation, energy efficiency, and life-cycle cost.

  12. Buxaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Buxaceae es reconocida en el Perú por presentar un género, Styloceras, y tres especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, todos arbustos. En este trabajo reconocemos un endemismo. Esta especie endémica se encuentra en la región Bosques Muy Húmedos Montanos, entre los 1800 y 1850 m de altitud. No está representada en el Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  13. [Linee guida italiane per il trattamento dell'alcolismo].

    Science.gov (United States)

    Ceccanti, Mauro; Iannitelli, Angela; Fiore, Marco

    2018-01-01

    RIASSUNTO. L'Europa è la regione con il più forte consumo di alcol al mondo, con la più elevata percentuale di malattie totali e morti premature alcol-correlate. In Italia, questo fenomeno coinvolge circa il 13% della popolazione oltre i 18 anni e oltre il 25% dei pazienti ospedalizzati. Sfortunatamente, solo il 5% di questi pazienti vengono riconosciuti come persone affette da disturbo da uso di alcol (DUA). Una scarsa conoscenza della malattia, la mancanza di accesso alle cure e le poche risorse messe a disposizione nella gestione del problema sono tra le principali cause di ritardo nella diagnosi, alla fine con conseguenze cliniche molto più importanti e costose da gestire. Alla luce di ciò, abbiamo deciso di dedicare questo numero speciale della Rivista di psichiatria a una serie di articoli riguardanti le linee guida italiane per il trattamento della dipendenza da alcol. Realizzate in collaborazione con numerosi esperti e importanti società scientifiche italiane come il Centro di Riferimento Alcologico della Regione Lazio (CRARL), la Società Italiana Tossicodipendenze (SITD), la Società italiana per il Trattamento dell'Alcolismo e le sue Complicanze (SITAC), la Società Italiana Psichiatria delle Dipendenze (SIPDip), la Società Italiana Patologie da Dipendenza (SIPaD) e l'Istituto di Biologia Cellulare e Neurobiologia (IBCN-CNR), queste linee guida forniscono agli operatori una serie di raccomandazioni basate su prove di efficacia volte ad aumentare la conoscenza e un uso appropriato dei farmaci per le persone affette da DUA. Con la possibilità di un continuo aggiornamento, l'obiettivo principale di queste linee guida sarà quello di garantire l'omogeneità dei trattamenti e un incremento qualitativo nell'assistenza dei pazienti affetti da DUA, così da ridurre le conseguenze psicosociali e sulla salute pubblica di questa importante malattia psichiatrica.

  14. Maxillaria jostii Dodson (Orchidaceae un nuevo registro para la Flora del Perú

    Directory of Open Access Journals (Sweden)

    Eric F. Rodríguez Rodríguez

    2013-12-01

    Full Text Available Se presenta a Maxillaria jostii Dodson (Orchidaceae como una nueva adición a la Flora del Perú procedente de los substratos de roca arenisca de la Cordillera subandina de Huarango (provincia San Ignacio, departamento Cajamarca, una prolongación sureña de la Cordillera del Cóndor rica en especies. Maxillaria jostii ha sido considerada como una especie endémica para Ecuador (Zamora-Chinchipe, Morona-Santiago; sin embargo, con el presente estudio se amplía su distribución geográfica hacia el Perú. Esta nueva contribución al conocimiento de la flora del país es el resultado del trabajo de campo y de herbario, gracias al Proyecto Binacional «Inventario Botánico de la Región de la Cordillera del Cóndor, Ecuador y Perú, 2005-2007», desarrollado entre las instituciones: MO, HUT, LOJA y QCNE. La contrastación específica se realizó con las especies documentadas en el «Catálogo de las Angiospermas y Gimnospermas del Perú» (Brako & Zarucchi 1993, «Diez años de adiciones a la flora del Perú: 1993-2003» (Ulloa Ulloa et al. 2004 y «Nuevas Adiciones de Angiospermas a la Flora del Perú» (Rodríguez et al. 2006b.

  15. Creació d'un portal web per la botiga de videojocs Lúdic

    OpenAIRE

    Martínez López, Manuel

    2008-01-01

    El projecte consistirà en la construcció d'un portal per la botiga de venda i lloguer de videojocs Lúdic de Lleida. La pàgina portarà incorporat un gestor de continguts que podrà fer servir l'administrador de la botiga per administrar els constinguts que es visualitzaran al portal.

  16. Sviluppo di un nuovo trigger con identificazione di quark-b per il canale Z($\

    CERN Document Server

    Donato, Silvio

    La ricerca del decadimento del bosone di Higgs H -> b b è uno dei canali più importanti per verificare se la particella di massa 125 GeV circa, recentemente scoperto da ATLAS e CMS, corrisponde effettivamente al bosone di Higgs previsto dal Modello Standard. Questo decadimento, insieme a H -> tau tau, è fondamentale per misurare l'accoppiamento del bosone con i fermioni. Il fondo di QCD rende poco sensibile l'osservazione di questo decadimento nella produzione diretta del bosone di Higgs. Per questo motivo il decadimento H -> b b viene ricercato quando l'Higgs è prodotto in associazione con i bosoni vettore W/Z, attraverso il cosiddetto processo di ``Higgs-strahlung''. Il decadimento leptonico dei bosoni vettore ad alto pT permette di ridurre il fondo di QCD e di realizzare trigger per osservare il canale. In questa tesi è stato realizzato un trigger per osservare il canale H + Z -> b b + nu nu nella regione a bassa EtMiss (fino a 80 GeV) con l'esperimento CMS. Per avere il trigger con un rate accettabi...

  17. Uranium-molybdenum alloys containing 0,5 to 3 per cent by weight of molybdenum

    International Nuclear Information System (INIS)

    Lehmann, J.

    1959-01-01

    The following properties have been determined in the new cast state of uranium alloys containing 0.5-1-1.8-2 and 3.5 per cent of molybdenum: micro-graphical aspect, crystalline structure, thermal expansion, the mechanical characteristics, behaviour when subjected to cyclic temperature variations, and heat treatment. The transformation curves have been established for continuous cooling at rates varying between 2.5 and 200 deg. C per minute, using a dilatation method for the alloys containing 1.0, 2.0 and 3.0 per cent Mo. T.T.T. curves have been traced for 0.5 and 1.0 per cent Mo alloys and the Ms points determined for alloys containing 2.0 and 3.0 par cent Mo. In this way it has been possible to show the different results of transformation, brought about either by nucleation and diffusion or by shear - the alloy containing 1 per cent Mo, give two martensites α' and α'' and the alloys containing 2 and 3 per cent Mo give one martensite with a band structure. (author) [fr

  18. Methods for preparation of mixtures of gases in air at the parts-per-billion to parts-per-million concentration range for calibration of monitors

    International Nuclear Information System (INIS)

    Karpas, Z.; Melloul, S.; Pollevoy, Y.; Matmor, A.

    1992-05-01

    Static and dynamic methods for generating mixture of gases and vapors in air at the parts-per-billion (ppb) to parts-per-million (ppm) concentration range were surveyed. The dynamic methods include: a dynamic flow and mixing system; injection of samples into large volumes of air; exponential dilution; permeation and diffusion tubes; and generation of the target gas by chemical reaction or electrolysis. The static methods include preparation of mixtures by weighing the components, by volumetric mixing and by partial pressure method. The principles governing the utilization of these methods for the appropriate applications were discussed, and examples in which they were used to calibrate an ion mobility spectrometer (IMS) were given. (authors)

  19. The Analysis of Income Per Capita Convergence on ASEAN Plus Three (APT) Countries

    OpenAIRE

    Fatiwetunusa, Any; Syamsurijal, Syamsurijal; Yuliana, Sa’adah

    2017-01-01

    The main objective of this study is to test the convergence of income per capita in APT countries through three models: absolute convergence, conditional convergence and sigma convergence. Regression analysis of panel data from 13 APT countries during the period of 2001-2014 is used to analysed to study problem. In absolute convergence model, the growth of real GDP per capita and initial real GDP are used as the variables, meanwhile, 8 variables such as the growth of real GPD per capita, init...

  20. Cost per severe accident as an index for severe accident consequence assessment and its applications

    International Nuclear Information System (INIS)

    Silva, Kampanart; Ishiwatari, Yuki; Takahara, Shogo

    2014-01-01

    The Fukushima Accident emphasizes the need to integrate the assessments of health effects, economic impacts, social impacts and environmental impacts, in order to perform a comprehensive consequence assessment of severe accidents in nuclear power plants. “Cost per severe accident” is introduced as an index for that purpose. The calculation methodology, including the consequence analysis using level 3 probabilistic risk assessment code OSCAAR and the calculation method of the cost per severe accident, is proposed. This methodology was applied to a virtual 1,100 MWe boiling water reactor. The breakdown of the cost per severe accident was provided. The radiation effect cost, the relocation cost and the decontamination cost were the three largest components. Sensitivity analyses were carried out, and parameters sensitive to cost per severe accident were specified. The cost per severe accident was compared with the amount of source terms, to demonstrate the performance of the cost per severe accident as an index to evaluate severe accident consequences. The ways to use the cost per severe accident for optimization of radiation protection countermeasures and for estimation of the effects of accident management strategies are discussed as its applications. - Highlights: • Cost per severe accident is used for severe accident consequence assessment. • Assessments of health, economic, social and environmental impacts are included. • Radiation effect, relocation and decontamination costs are important cost components. • Cost per severe accident can be used to optimize radiation protection measures. • Effects of accident management can be estimated using the cost per severe accident

  1. Optimization of solar cell contacts by system cost-per-watt minimization

    Science.gov (United States)

    Redfield, D.

    1977-01-01

    New, and considerably altered, optimum dimensions for solar-cell metallization patterns are found using the recently developed procedure whose optimization criterion is the minimum cost-per-watt effect on the entire photovoltaic system. It is also found that the optimum shadow fraction by the fine grid is independent of metal cost and resistivity as well as cell size. The optimum thickness of the fine grid metal depends on all these factors, and in familiar cases it should be appreciably greater than that found by less complete analyses. The optimum bus bar thickness is much greater than those generally used. The cost-per-watt penalty due to the need for increased amounts of metal per unit area on larger cells is determined quantitatively and thereby provides a criterion for the minimum benefits that must be obtained in other process steps to make larger cells cost effective.

  2. World relation per capita between income and emission of carbon dioxide

    Directory of Open Access Journals (Sweden)

    Fernando Artico Bigarani1

    2014-12-01

    Full Text Available The aim of this article is to verify the existence of relation per capita between emission of carbon dioxide and the growth of the income. The used methodology is the exploratory analysis of space data for the years of 1994 and 2009. By means of maps and of the Index of Moran one searched to observe the existence of space autocorrelation enters carbonic gas emission the per capita and per capita Gross domestic product of the countries of the Europe and Africa and to verify the space existence of clusters. The analysis of the results presented significant space autocorrelation between the studied variable and allowed the space identification of clusters in the Europe and Africa. The conclusion confirms the theory of the Curve of Ambient Kuznets and also it was identified that the protocol of Kyoto was capable to promote alterations in univariate clusters analyzed in the period.

  3. Dose per unit area - a study of elicitation of nickel allergy

    DEFF Research Database (Denmark)

    Fischer, Louise Arup; Menné, Torkil; Johansen, Jeanne Duus

    2007-01-01

    BACKGROUND: Experimental sensitization depends upon the amount of allergen per unit skin area and is largely independent of the area size. OBJECTIVES: This study aimed at testing if this also applies for elicitation of nickel allergy. PATIENTS/METHODS: 20 nickel allergic individuals were tested...... with a patch test and a repeated open application test (ROAT). Nickel was applied on small and large areas. The varying parameters were area, total dose and dose per unit area. RESULTS: In the patch test, at a low concentration [15 microg nickel (microg Ni)/cm(2)], there were significantly higher scores...... on the large area with the same dose per area as the small area. At higher concentrations of nickel, no significant differences were found. In the ROAT at low concentration (6.64 microg Ni/cm(2)), it was found that the latency period until a reaction appeared was significantly shorter on the large area...

  4. Identità visiva e narrazione in un percorso MOOC per docenti

    Directory of Open Access Journals (Sweden)

    Letizia Cinganotto

    2015-09-01

    Full Text Available Il contributo mira a illustrare un esempio di MOOC per docenti realizzato in un contesto internazionale. In particolare, il focus è rappresentato dalla documentazione e riflessione sul percorso formativo dei docenti attraverso l’uso del diario, componente essenziale per la rielaborazione e reinterpretazione dell’esperienza ai fini dell’arricchimento e della crescita personale e professionale. Le tecnologie multimediali e multimodali offrono la possibilità di costruire varie tipologie di diari all’interno di percorsi di formazione online. In particolare, verranno presi in considerazione alcuni esempi di diari e ne saranno illustrate le caratteristiche principali, dettagliando l’uso di alcuni tool per la rappresentazione narrativa e visiva. L’articolo prende le mosse da un breve quadro di riferimento teorico sulla funzione dei MOOC nella formazione dei docenti e sull’importanza della meta-riflessione ai fini della costruzione del profilo del “professionista riflessivo”.

  5. Strutturazione dell’A.I.M. [Archivio informativo multimediale] per il progetto

    Directory of Open Access Journals (Sweden)

    Cristiana Bartolomei

    2011-06-01

    Full Text Available Il nostro obiettivo è quello di individuare e integrare una serie di tecnologie e strategie operative per la creazione di un’architettura digitale di ultima generazione, in grado di fornire un archivio informativo multimediale (A.I.M. virtualmente illimitato e scalabile per files multimediali multi formato (foto, disegni ecc. e modelli 3D. Sostanzialmente, si tratta di applicazioni di Database: tutti i beni considerati devono essere “inventariati” in modo opportuno e queste schede di inventario devono essere organizzate in modo utile. L’obiettivo dello strumento A.I.M. è dimostrare che è possibile integrare diverse fonti d’informazioni, continuamente aggiornabili e dotate di una specifica interfaccia di gestione e di ricerca, destinate a supportare dinamicamente il livello divulgativo e informativo e vuole rappresentare, per restauratori, conservatori e gestori in genere dei beni culturali, un valido strumento di monitoraggio dei restauri.

  6. Ear recognition from one sample per person.

    Directory of Open Access Journals (Sweden)

    Long Chen

    Full Text Available Biometrics has the advantages of efficiency and convenience in identity authentication. As one of the most promising biometric-based methods, ear recognition has received broad attention and research. Previous studies have achieved remarkable performance with multiple samples per person (MSPP in the gallery. However, most conventional methods are insufficient when there is only one sample per person (OSPP available in the gallery. To solve the OSPP problem by maximizing the use of a single sample, this paper proposes a hybrid multi-keypoint descriptor sparse representation-based classification (MKD-SRC ear recognition approach based on 2D and 3D information. Because most 3D sensors capture 3D data accessorizing the corresponding 2D data, it is sensible to use both types of information. First, the ear region is extracted from the profile. Second, keypoints are detected and described for both the 2D texture image and 3D range image. Then, the hybrid MKD-SRC algorithm is used to complete the recognition with only OSPP in the gallery. Experimental results on a benchmark dataset have demonstrated the feasibility and effectiveness of the proposed method in resolving the OSPP problem. A Rank-one recognition rate of 96.4% is achieved for a gallery of 415 subjects, and the time involved in the computation is satisfactory compared to conventional methods.

  7. Ear recognition from one sample per person.

    Science.gov (United States)

    Chen, Long; Mu, Zhichun; Zhang, Baoqing; Zhang, Yi

    2015-01-01

    Biometrics has the advantages of efficiency and convenience in identity authentication. As one of the most promising biometric-based methods, ear recognition has received broad attention and research. Previous studies have achieved remarkable performance with multiple samples per person (MSPP) in the gallery. However, most conventional methods are insufficient when there is only one sample per person (OSPP) available in the gallery. To solve the OSPP problem by maximizing the use of a single sample, this paper proposes a hybrid multi-keypoint descriptor sparse representation-based classification (MKD-SRC) ear recognition approach based on 2D and 3D information. Because most 3D sensors capture 3D data accessorizing the corresponding 2D data, it is sensible to use both types of information. First, the ear region is extracted from the profile. Second, keypoints are detected and described for both the 2D texture image and 3D range image. Then, the hybrid MKD-SRC algorithm is used to complete the recognition with only OSPP in the gallery. Experimental results on a benchmark dataset have demonstrated the feasibility and effectiveness of the proposed method in resolving the OSPP problem. A Rank-one recognition rate of 96.4% is achieved for a gallery of 415 subjects, and the time involved in the computation is satisfactory compared to conventional methods.

  8. 38 CFR 61.32 - Ranking non-capital grant recipients for per diem.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Ranking non-capital grant... AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.32 Ranking non-capital grant... ranking. (c) All applicants responding to a NOFA for “Per Diem Only” will be subject to the ranking method...

  9. The T10 beam produces a few hits per event. In ALICE the SSD will have to cope with many hits per strip. In the three centimeters of aluminium the beam will produce many secondary particles. This increases the chance of multiple hits per strip, although not to the level in ALICE.

    CERN Multimedia

    Nooren, G.

    2004-01-01

    The T10 beam produces a few hits per event. In ALICE the SSD will have to cope with many hits per strip. In the three centimeters of aluminium the beam will produce many secondary particles. This increases the chance of multiple hits per strip, although not to the level in ALICE.

  10. Bancarización pública y crecimiento económico regional en el Perú

    OpenAIRE

    Burneo Farfan, Kurt Johnny

    2009-01-01

    L'objectiu d'aquesta recerca és avaluar si la bancarització pública, definida per l'evolució del programa de préstecs Multired del banc estatal del Perú, es constitueix como un factor rellevant per explicar la dinàmica del creixement econòmic regional en el període d'octubre de 2001 a juliol de 2006. Els resultats d'aquesta recerca es poden constituir com a inputs útils per a la formulació de les polítiques públiques en l'àmbit financer. La literatura identifica la bancarització amb el grau d...

  11. Modellistica numerica per problemi differenziali

    CERN Document Server

    Quarteroni, Alfio

    2016-01-01

    In questo testo si introducono i concetti di base per la modellistica numerica di problemi differenziali alle derivate parziali. Si considerano le classiche equazioni lineari ellittiche, paraboliche ed iperboliche, ma anche altre equazioni, quali quelle di diffusione e trasporto, di Navier-Stokes e le leggi di conservazione. Si forniscono inoltre numerosi esempi fisici che stanno alla base di tali equazioni. Quindi si analizzano metodi di risoluzione numerica basati su elementi finiti (continui e discontinui), differenze finite, volumi finiti, metodi spettrali (continui e discontinui), nonché strategie di approssimazione più avanzate basate sui metodi di decomposizione di domini, i metodi a basi ridotte o quelli di risoluzione di problemi di controllo ottimale. In particolare vengono discussi gli aspetti algoritmici e di implementazione al calcolatore e si forniscono diversi programmi di semplice utilizzo. Il testo non presuppone una approfondita conoscenza matematica delle equazioni alle derivate parziali:...

  12. Berberidaceae endémicas del Perú

    OpenAIRE

    Ulloa Ulloa, Carmen; Sagástegui, Abundio; Sánchez, Isidoro

    2013-01-01

    The Berberidaceae are represented in Peru by 32 species in the genus Berberis (Brako & Zarucchi, 1993), most of them shrubs. Most of the 14 endemic species grow in the Mesoandean region, between 2000 and 4200 m elevation. Two of these endemic species have been reported in the Peruvian System of Protected Natural Areas. La familia Berberidaceae es reconocida en el Perú con un género, Berberis, y 32 especies (Brako & Zarucchi, 1993), mayormente arbustos. Esta familia incluye 14 endemismos. L...

  13. Modeling per capita state health expenditure variation: state-level characteristics matter.

    Science.gov (United States)

    Cuckler, Gigi; Sisko, Andrea

    2013-01-01

    In this paper, we describe the methods underlying the econometric model developed by the Office of the Actuary in the Centers for Medicare & Medicaid Services, to explain differences in per capita total personal health care spending by state, as described in Cuckler, et al. (2011). Additionally, we discuss many alternative model specifications to provide additional insights for valid interpretation of the model. We study per capita personal health care spending as measured by the State Health Expenditures, by State of Residence for 1991-2009, produced by the Centers for Medicare & Medicaid Services' Office of the Actuary. State-level demographic, health status, economic, and health economy characteristics were gathered from a variety of U.S. government sources, such as the Census Bureau, Bureau of Economic Analysis, the Centers for Disease Control, the American Hospital Association, and HealthLeaders-InterStudy. State-specific factors, such as income, health care capacity, and the share of elderly residents, are important factors in explaining the level of per capita personal health care spending variation among states over time. However, the slow-moving nature of health spending per capita and close relationships among state-level factors create inefficiencies in modeling this variation, likely resulting in incorrectly estimated standard errors. In addition, we find that both pooled and fixed effects models primarily capture cross-sectional variation rather than period-specific variation.

  14. Effects of different per translational kinetics on the dynamics of a core circadian clock model.

    Science.gov (United States)

    Nieto, Paula S; Revelli, Jorge A; Garbarino-Pico, Eduardo; Condat, Carlos A; Guido, Mario E; Tamarit, Francisco A

    2015-01-01

    Living beings display self-sustained daily rhythms in multiple biological processes, which persist in the absence of external cues since they are generated by endogenous circadian clocks. The period (per) gene is a central player within the core molecular mechanism for keeping circadian time in most animals. Recently, the modulation PER translation has been reported, both in mammals and flies, suggesting that translational regulation of clock components is important for the proper clock gene expression and molecular clock performance. Because translational regulation ultimately implies changes in the kinetics of translation and, therefore, in the circadian clock dynamics, we sought to study how and to what extent the molecular clock dynamics is affected by the kinetics of PER translation. With this objective, we used a minimal mathematical model of the molecular circadian clock to qualitatively characterize the dynamical changes derived from kinetically different PER translational mechanisms. We found that the emergence of self-sustained oscillations with characteristic period, amplitude, and phase lag (time delays) between per mRNA and protein expression depends on the kinetic parameters related to PER translation. Interestingly, under certain conditions, a PER translation mechanism with saturable kinetics introduces longer time delays than a mechanism ruled by a first-order kinetics. In addition, the kinetic laws of PER translation significantly changed the sensitivity of our model to parameters related to the synthesis and degradation of per mRNA and PER degradation. Lastly, we found a set of parameters, with realistic values, for which our model reproduces some experimental results reported recently for Drosophila melanogaster and we present some predictions derived from our analysis.

  15. Dependence of energy per molecule on sputtering yields with reactive gas cluster ions

    International Nuclear Information System (INIS)

    Toyoda, Noriaki; Yamada, Isao

    2010-01-01

    Gas cluster ions show dense energy deposition on a target surface, which result in the enhancement of chemical reactions. In reactive sputtering with gas cluster ions, the energy per atom or molecule plays an important role. In this study, the average cluster size (N, the number of atoms or molecules in a cluster ion) was controlled; thereby the dependences of the energy per molecule on the sputtering yields of carbon by CO 2 cluster ions and that of Si by SF 6 /Ar mixed gas cluster ions were investigated. Large CO 2 cluster ions with energy per molecule of 1 eV showed high reactive sputtering yield of an amorphous carbon film. However, these ions did not cause the formation of large craters on a graphite surface. It is possible to achieve very low damage etching by controlling the energy per molecule of reactive cluster ions. Further, in the case of SF 6 /Ar mixed cluster ions, it was found that reactive sputtering was enhanced when a small amount of SF 6 gas (∼10%) was mixed with Ar. The reactive sputtering yield of Si by one SF 6 molecule linearly increased with the energy per molecule.

  16. Takistused loova lammutamise teel / Per Högselius ; interv. Kristjan Otsmann

    Index Scriptorium Estoniae

    Högselius, Per

    2006-01-01

    Loova lammutamise teooria uurija innovatsiooniteadlane Per Högselius selgitab, miks on olemasolevasse, kuid iganenud tehnoloogiasse investeerimine innovatsioonile takistuseks ning põhjendab loova lammutamise vajalikkust

  17. Narrativa audiovisual i cinema d'animació per ordinador

    OpenAIRE

    Duran Castells, Jaume

    2009-01-01

    DE LA TESI:Aquesta tesi doctoral estudia les relacions entre la narrativa audiovisual i el cinema d'animació per ordinador i fa una anàlisi al respecte dels llargmetratges de Pixar Animation Studios compresos entre 1995 i 2006.

  18. Dividend Per Share, Retained Earnings, Book Value And Total Debt On Stock Price: Approximation Valuation Model Dividend Per Share, Retained Earnings, Book Value, dan Total Debt terhadap Harga Saham: Pendekatan Valuation Model.

    OpenAIRE

    khikmah, Khoirul

    2011-01-01

    This study examines to dividend per share, retained earnings, book valueand total debt on stock price: approximation valuation model. Data in this studyare manufacture firms listed on Indonesia Stock Exchange in 2005 – 2008. Linearregression analysis used to analysis this data. Result of regression analysis findsthat dividend per share, retained earnings, book value and total debt on stock pricehave significant effect to stock price. Dividend per share and book value havesignificant effect in...

  19. Visitantes florais de Lagerstroemia speciosa Pers: (Lythraceae Floral visitors in Lagerstroemia speciosa Pers: (Lythraceae

    Directory of Open Access Journals (Sweden)

    Maria de Jesus Vitali-Veiga

    1999-06-01

    Full Text Available Studies were carried out with Lagerstroemia speciosa Pers. on floral reproductive systems, diversity and constancy of visiting insects at different hours of day, the behaviour of these insects at the flowers and the influence of these environmental factors in relation to their visits. The fenology, anthesis and others particularity of this vegetal species was studied. A great diversity of insects was verified visiting the flowers with the predominance of bees. The most frequent and constant species encountered were: Nannotrigona testaceicornis (Lepeletier, 1836 (40,2%, Tetragonisca angustula (Latreille, 1811 (16,9%, Apis mellifera Linnaeus, 1758 (11,8%, Plebeia droryana (Friese, 1900 (9,1 % e Exomalopsis fulvofasciata (Smith, 1879 (8,5%. The blossoms possessis features of melittophily syndrome and diurnal anthesis. The environmental factors influence the insects foraging activity, mainly temperature, light, time of day, humidity and wind speed. The effective pollinators were the large insects like Bombus morio (Swederus, 1787, Bombus atratus (Franklin, 1913, Centris tarsata (Smith, 1874, Centris flavifrons Fabricius, 1775, Xylocopa suspecta Camargo & Moure, 1988, Xylocopa frontalis (Olivier, 1789 and Eulaema nigrita Lepeletier, 1841.

  20. P. Ortoleva, Dal sesso al gioco. Un’ossessione per il XXI° secolo?

    Directory of Open Access Journals (Sweden)

    Mauro Salvador

    2013-03-01

    Full Text Available In questo pamphlet edito da Espress per la collana “Tazzine di caffé con panna” Ortoleva riprende le fila del discorso avviato ne Il secolo dei media (2008. L’autore riparte dalla liberazione sessuale e dalla diffusione della pornografia della seconda metà del Novecento per giungere a parlare del contemporaneo processo di “ludicizzazione del reale”

  1. Multiuser switched scheduling systems with per-user threshold and post-user selection

    KAUST Repository

    Nam, Haewoon

    2010-06-01

    A multiuser switched diversity scheduling scheme with per-user feedback threshold is proposed in this paper. Unlike the conventional multiuser switched diversity scheduling scheme where a single threshold is used by all the users in order to determine whether to transmit a feedback, the proposed scheme deploys per-user threshold, where each user uses a potentially different threshold than other users thresholds. This paper first provides a generic analytical framework for the optimal feedback thresholds in a closed form. Then we investigates the impact of user sequence strategies and post selection strategies on the performance of the multiuser switched scheduling scheme with per-user threshold. Numerical and simulation results show that the proposed scheme provides a higher system capacity compared to the conventional scheme. © 2010 IEEE.

  2. Multiuser switched scheduling systems with per-user threshold and post-user selection

    KAUST Repository

    Nam, Haewoon; Alouini, Mohamed-Slim

    2010-01-01

    A multiuser switched diversity scheduling scheme with per-user feedback threshold is proposed in this paper. Unlike the conventional multiuser switched diversity scheduling scheme where a single threshold is used by all the users in order to determine whether to transmit a feedback, the proposed scheme deploys per-user threshold, where each user uses a potentially different threshold than other users thresholds. This paper first provides a generic analytical framework for the optimal feedback thresholds in a closed form. Then we investigates the impact of user sequence strategies and post selection strategies on the performance of the multiuser switched scheduling scheme with per-user threshold. Numerical and simulation results show that the proposed scheme provides a higher system capacity compared to the conventional scheme. © 2010 IEEE.

  3. Aspleniaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available Esta familia es reconocida en el Perú con un solo género, Asplenium y más de 65 especies (Tryon & Stolze, 1993; Smith et al., 2005. Aspleniaceae está representada en un amplio rango de ambientes; sin embargo, las dos especies endémicas reconocidas ocupan principalmente los bosques de las regiones del Bosque Húmedo Montano y Premontano, entre los 700 y 2500 m de altitud. Solamente, una de estas especies cuenta con poblaciones en un área protegida.

  4. Emprendimiento rural femenino en el Perú

    OpenAIRE

    Solórzano Loayza, Ronald A.; Altamirano Romero, Juan C.; Quezada Torres, Juan F.; Aranda Álvarez, Cynthia M.

    2014-01-01

    viii, 187 h. : il. ; 30 cm. En el Perú, las mujeres empresarias representan una proporción importante en la actividad económica; sin embargo, ha sido un caso poco estudiado dado que la información existente es escasa, y por tanto la información estadística y el perfilamiento cualitativo actual no permite entender su realidad para profundizar en su desarrollo. En el contexto rural, el que una mujer pobre participe en la actividad emprendedora puede ser una oportunidad para sa...

  5. Costaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Costaceae es reconocida en el Perú por presentar tres géneros y 26 especies (Brako & Zarucchi, 1993, todas ellas hierbas. En este trabajo reconocemos tres endemismos en dos géneros. Un género, Monocostus, es endémico. Las especies endémicas ocupan los bosques de la llanura amazónica y bosques premontanos húmedos, entre los 300 y 800 m de altitud. Ninguno de estos taxones se encuentra representado en un área natural protegida.

  6. Olacaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Olacaceae es reconocida en el Perú por presentar nueve géneros y 23 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, la mayoría árboles y arbustos. En este trabajo reconocemos un endemismo en el género Aptandra. Esta especie se encuentra en la región Bosques Húmedos Amazónicos, entre los 100 y 150 m de altitud. No está registrada en el Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  7. SU-E-T-296: Single Field Per Day Vs. Multiple Fields Per Day and the Impact On BED in Proton Therapy Treatment

    International Nuclear Information System (INIS)

    Grantham, K; Wooten, H; Zhao, T; Klein, E

    2014-01-01

    Purpose: A common practice, in proton therapy, is to deliver a rotating subset of fields from the treatment plan for the daily fractions. This study compares the impact this practice has on the biological effective dose (BED) versus delivering all planned fields daily. Methods: For two scenarios (a phantom with a geometry approximating the anatomy of a prostate treatment with opposing lateral beams, and a clinical 3-field brain treatment), treatment plans were produced in Eclipse (Varian) to simulate delivery of one, two, and three fields per fraction. The RT-Dose file, structure set, and α/β ratios were processed using in-house MATLAB code to return a new RT-Dose file containing the BED (including a proton RBE of 1.1) which was imported back into Eclipse for analysis. Results: For targets and regions of field overlap in the treatment plan, BED is not affected by delivery regimen. In the phantom, BED in the femoral heads showed increased by 20% when a single field was used rather than two fields. In the brain treatment, the minimum BED to the left optic nerve and the pituitary gland increased by 13% and 10% respectively, for a one-field regime compared to three-fields per fraction. Comparing the two-field and threefield regimes, the optic nerve BED was not significantly affected and the minimum pituitary BED was 4% higher for two fields per day. Conclusion: Hypo-fractionation effects, in regions of non-overlap of fields, significantly increase the BED to the involved tissues by as much as 20%. Care should be taken to avoid inadvertently sacrificing plan effectiveness in the interest of reduced treatment time

  8. Estimates of per capita exposure to substances migrating from canned foods and beverages.

    Science.gov (United States)

    Dionisi, G; Oldring, P K T

    2002-09-01

    A study was undertaken by European industry to estimate the consumption of canned beverages and foodstuffs. European can production data were used with adjustments for imports into and out of the EU. It was further assumed that can production, with adjustments, equalled consumption. Owing to the lack of actual consumption country-by-country or household-by-household data throughout Europe, only per capita estimates of consumption were possible. Data were compiled country-by-country for seven major can-producing EU Member States and for eight different types of canned food and two types of canned beverage (beer and soft drinks). The per capita consumption of canned foods was 1.1 cans/person/week, and consumption of canned fish was estimated as 2.2 kg/person/year. The estimate of per capita consumption of canned food was 62 g/person/day or 22.6 kg/person/year. Canned beverages account for about 60% of the consumption of canned foodstuffs. The usefulness of per capita consumption of beverages is questionable because consumption habits may vary more widely than those for canned foods. However, as the migration into beverages is insignificant, these data were added for completeness. Per capita consumption of canned beverages is 67 cans/person/year or 61 g/person/day. From the average can sizes, the surface area of the cans consumed was estimated. The per capita surface area exposure was 0.55 dm(2)/person/day for canned foods and 0.55 dm(2)/person/day for canned beverages, giving 1.1 dm(2)/person/day. Migration of a substance at 0.02 mg dm(2) gives an exposure of 0.01 mg/person/day assuming a per capita consumption, using a surface area model. Migration at 0.12 mg kg(-1) in food gives an exposure of 0.007 mg/person/day using a weight model. Both models assumed migration into all food types at the same level, which is highly unrealistic. Exposure to BADGE from canned foods has been used as a case study. The best estimate for a worst case per capita exposure to BADGE and

  9. Ten per cent polarized optical emission from GRB 090102.

    Science.gov (United States)

    Steele, I A; Mundell, C G; Smith, R J; Kobayashi, S; Guidorzi, C

    2009-12-10

    The nature of the jets and the role of magnetic fields in gamma-ray bursts (GRBs) remains unclear. In a baryon-dominated jet only weak, tangled fields generated in situ through shocks would be present. In an alternative model, jets are threaded with large-scale magnetic fields that originate at the central engine and that accelerate and collimate the material. To distinguish between the models the degree of polarization in early-time emission must be measured; however, previous claims of gamma-ray polarization have been controversial. Here we report that the early optical emission from GRB 090102 was polarized at 10 +/- 1 per cent, indicating the presence of large-scale fields originating in the expanding fireball. If the degree of polarization and its position angle were variable on timescales shorter than our 60-second exposure, then the peak polarization may have been larger than ten per cent.

  10. eBook: Temps líquids per a les biblioteques públiques

    Directory of Open Access Journals (Sweden)

    Juan Soriano, Emili

    2012-06-01

    Full Text Available Què fem amb els llibres electrònics?, és la pregunta que s’estan plantejant molts bibliotecaris mentre assisteixen perplexos a una competició frenètica sobre la distribucióde continguts digitals i a la cursa accelerada de les empreses tecnològiques per presentar dispositius de lectura electrònica amb més prestacions.La resposta no és senzilla, per això, les biblioteques públiques contemplen aquesta nova realitat amb un cert neguit, i alhora, com un nou repte per continuar sent una institució cultural central en la vida de les persones posicionant-se i adaptant els serveis i els continguts a les noves demandes dels usuaris, tenint present que, a dia de hui, el món digital i el món imprès no són excloents sinó complementaris.El present article intenta analitzar aquesta nova realitat i planteja algunes de les accions a adoptar per part de les biblioteques públiques amb les incerteses pròpies dels “tempslíquids” que travessa la nostra societat.

  11. El sistema eléctrico de interconexión Perú-Ecuador y su incidencia en los costos totales de energía eléctrica en el Perú

    OpenAIRE

    Eusebio Gonzales, Fredy R.; Eusebio Gonzales, Fredy R.; Aragón Castro, Ismael Valerio; Eusebio Gonzales, Fredy R.

    2013-01-01

    En la presente investigación se avalúa y analiza la relación causa-efecto de las variables: “El sistema eléctrico de interconexión Perú-Ecuador” y “los costos totales de energía eléctrica en el Perú”, durante el periodo 2012-2015. Se encuentra como resultado que los costos de la interconexión afectan negativamente los costos de la energía eléctrica en el Perú, puesto que el sistema tarifario traslada éstos a la tarifa mediante el cargo por peaje del Sistema Principal de Transmisión. Sin embar...

  12. Verde urbano e processi ambientali: per una progettazione di paesaggio multifunzionale

    Directory of Open Access Journals (Sweden)

    Raffaele Pelorosso

    2013-04-01

    Full Text Available L’impermeabilizzazione delle superfici determina un’alterazione del sistema idrologico, con un incremento dei volumi e dei picchi dei deflussi delle acque meteoriche. Il fenomeno è destinato a progredire, sia per il contributo che vi deriva dalla costante crescita delle superfici urbanizzate (urban sprawl, sia per i cambiamenti climatici in atto, che accentuano la frequenza delle piogge critiche. Una serie di misure e tecniche (Best Management Practices, BMPs sono state sviluppate per la gestione sostenibile delle acque meteoriche urbane. Alcune  BMPs (es: verde pensile, bacini di detenzione/ritenzione, zone umide possono svolgere inoltre una funzione ecologica (divenendo habitat per specie animali e vegetali, di termoregolazione, estetica e di promozione del capitale sociale. È quindi necessario sperimentare metodologie di progettazione e gestione del verde urbano e periurbano, la cui multifunzionalità consente di perseguire la strada della sostenibilità ambientale. Su tale traccia, questo lavoro presenta un percorso metodologico orientato a valutare alcune strategie integrate di controllo dei deflussi urbani, attraverso l’aumento della permeabilità di alcune parti sensibili di città. Il verde, quindi, non è visto come semplice infrastruttura necessaria a soddisfare generici standard urbanistici, ma ne sono analizzate le funzionalità, in questa prima fase di carattere idrologico, ma che, in prospettiva, con la stessa armatura verde, esso può assumere un ruolo ecologico, sociale, di mitigazione del clima e di emissione di gas clima-alteranti.

  13. The need for drugged driving per se laws: a commentary.

    Science.gov (United States)

    DuPont, Robert L; Voas, Robert B; Walsh, J Michael; Shea, Corinne; Talpins, Stephen K; Neil, Mark M

    2012-01-01

    Triggered by the new federal commitment announced by the Office of National Drug Control Policy (ONCDP) to encourage states to enact drugged driving per se laws, this article reviews the reasons to establish such laws and the issues that may arise when trying to enforce them. A review of the state of drunk driving per se laws and their implications for drugged driving is presented, with a review of impaired driving enforcement procedures and drug testing technology. Currently, enforcement of drugged driving laws is an adjunct to the enforcement of laws regarding alcohol impairment. Drivers are apprehended when showing signs of alcohol intoxication and only in the relatively few cases where the blood alcohol concentration of the arrested driver does not account for the observed behavior is the possibility of drug impairment pursued. In most states, the term impaired driving covers both alcohol and drug impairment; thus, driver conviction records may not distinguish between the two different sources of impairment. As a result, enforcement statistics do not reflect the prevalence of drugged driving. Based on the analysis presented, this article recommends a number of steps that can be taken to evaluate current drugged driving enforcement procedures and to move toward the enactment of drug per se laws.

  14. Mentalità stratigrafica e progetti per la conoscenza e per la conservazione

    Directory of Open Access Journals (Sweden)

    Pertot, Gianfranco

    2002-12-01

    Full Text Available The present work is made to show a didactic experience acquired by the authors at the Universities of Milan and Brescia (Italy in the sphere of teaching Architectural Restoration. The peculiar aspect of research is the attempt to apply not only the procedures of archeological stratigraphy but also the “stratigraphical mentality” to the project of conservation and re-use of architecture. Introducing and using, for example, new models of archeological stratigraphy lecture of the buildings expressed for the requirements of conservation and re-use, in proposing the new index-codes of Phases Intersides and Associated Stratigraphical Unity. The authors finally put forward some comments about the so called “archaological” Restoration.Gli autori presentano i risultati più significativi di una ricerca svolta presso le Università di Milano e di Brescia, nell’ambito dei corsi di Restauro architettonico. Fra i principali obiettivi dello studio e delle esperienze didattiche correlate vi è il tentativo non solo di utilizzare le procedure dell’archeologia stratigrafica, per quanto utile e possibile, nella complessa serie di operazioni che segna la redazione di un progetto di conservazione e di riuso, ma di trasferirvi anche quella che si può definire come “mentalità stratigrafica”. In particolare considerando nuovi codici, quali le Interfacce di Fase e le Unità Stratigrafiche Associate. A corredo di queste argomentazioni vengono anche svolte alcune considerazioni in merito al cosiddetto “Restauro archeologico”

  15. Liberales, protestantes y masones, modernidad y tolerancia religiosa. Perú, siglo XIX. [Reseña

    OpenAIRE

    Cuesta-Alonso, M.R. (Marcelino R.)

    1999-01-01

    Reseña de: Fernando ARMAS ASÍN, Liberales, protestantes y masones, modernidad y tolerancia religiosa. Perú, siglo XIX, Centro de Estudios Regionales Andinos «Bartolomé de las Casas» - Pontificia Universidad Católica del Perú, Cusco (Perú) 1998, 298 pp.

  16. Per-energy capacity and handoff strategies in macro-femto cells environment

    KAUST Repository

    Leon, Jaime; Bader, Faouzi; Alouini, Mohamed-Slim

    2012-01-01

    The effect of smaller cells being placed in a heterogenous network can improve the way energy is spent in a system. Handoff strategies, bandwidth allocation and path loss calculations in different scenarios show how this is possible as the size of the cell is decreased. As a result, users can experience the same or better capacities while maximising the capacity per unit energy spent. The per-energy capacity metric is introduced as a suitable handoff strategy that considers the energy spent as an important criterion. © 2012 IEEE.

  17. Planeamiento estratégico para Aidisa Perú S.A.C.

    OpenAIRE

    Dileo Pinillos, Roberto Carlos; Diaz Amayo, Jorge Luis; Gordillo Andrade, Luis; Ubillús Galarreta, Eduardo Antonio

    2016-01-01

    xvii, 106 h. : il. ; 30 cm. El plan estratégico desarrollado para Aidisa Perú S.A.C. se enmarca en la industria de distribución de productos de consumo masivo, específicamente en el canal tradicional abarcando a clientes minoristas y mayoristas. Para el desarrollo del mismo se trabajó conjuntamente con un grupo de empleados de cada operación de Aidisa Perú seleccionados en base a su conocimiento de la industria y de la empresa, realizándose además una exhaustiva investigació...

  18. Per-energy capacity and handoff strategies in macro-femto cells environment

    KAUST Repository

    Leon, Jaime

    2012-04-01

    The effect of smaller cells being placed in a heterogenous network can improve the way energy is spent in a system. Handoff strategies, bandwidth allocation and path loss calculations in different scenarios show how this is possible as the size of the cell is decreased. As a result, users can experience the same or better capacities while maximising the capacity per unit energy spent. The per-energy capacity metric is introduced as a suitable handoff strategy that considers the energy spent as an important criterion. © 2012 IEEE.

  19. Buddlejaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Buddlejaceae es reconocida en el Perú por presentar dos géneros y 16 especies (Norman, 2000; Ulloa Ulloa et al., 2004, principalmente arbustos. En este trabajo reconocemos dos especies endémicas en el género Buddleja. Estos taxones endémicos se encuentran en las regiones Mesoandina, Puna Húmeda y Seca y Páramo, entre los 2650 y 3900 m de altitud. Una de estas dos especies se encuentra representada dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  20. Tropaeolaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available Esta es la familia de la «mashua». La familia Tropaeolaceae es reconocida en el Perú por presentar un género, Tropaeolum, y 24 especies (Brako & Zarucchi, 1993, todas herbáceas y bejucos. En este trabajo reconocemos 10 especies endémicas, las cuales se encuentran principalmente en las regiones Bosques Muy Húmedos Montanos y Mesoandina, entre los 1800 y 3200 m de altitud. Una especie, aparentemente, se encuentra representada dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  1. Burmanniaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Burmanniaceae es reconocida en el Perú por presentar ocho géneros y 16 especies (Brako & Zarucchi, 1993, principalmente hierbas saprófitas. En este trabajo reconocemos un endemismo en el genero Burmannia. Esta especie endémica posee un amplio grado de adaptación ambiental, habiéndosele localizado en las vertientes occidentales, valles interandinos, páramos y bosques montanos orientales, entre los 1200 y 4100 m de altitud. Esta especie se encuentra representada en un área natural protegida.

  2. Scrophulariaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Scrophulariaceae es reconocida en el Perú por presentar alrededor de 18 géneros y 35 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, principalmente herbáceas. En este trabajo reconocemos dos especies endémicas en dos géneros, las cuales se encuentran principalmente en la región Bosques Húmedos Amazónicos, entre los 200 y 1000 m de altitud. Ninguna de las especies endémicas se encuentra representada dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  3. Clúster d'ordinadors per estacions base

    OpenAIRE

    Paños Marín, Albert

    2011-01-01

    Es planteja el desenvolupament d'un cluster d'ordinadors que pugui dur a terme la computació intensiva necessària en una estació base. El computador de base a analitzar es la PS3 utilitzant les eines de programació disponible i sota entorn Linux. Les activitats que es duran a terme son: Iniciació a l'entorn de desenvolupament per la PS3. Anàlisi de les prestacions que es poden aconseguir i identificació de les limitacions en el desenvolupament de codi paralelitzable. Definició i posada en mar...

  4. Vochysiaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Vochysiaceae es reconocida en el Perú por presentar cuatro géneros y 32 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, todas árboles. En este trabajo reconocemos dos especies endémicas en el género Qualea. Estas especies endémicas han sido encontradas en la región Bosques Húmedos Amazónicos, entre los 100 y 160 m de altitud. Ninguna especie endémica se encuentra representada dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  5. Flacourtiaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Flacourtiaceae es reconocida en el Perú por presentar 19 géneros y 65 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, mayormente arbustos y árboles. En este trabajo reconocemos tres especies endémicas en dos géneros, las cuales ocupan la región de los Bosques Muy Húmedos Montanos, entre los 2300 y 3600 m de altitud. Solamente una de estas especies se encuentra representada en el Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  6. Cyclanthaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Cyclanthaceae es reconocida en el Perú por presentar nueve géneros y 37 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, mayormente hierbas y lianas. En este trabajo reconocemos siete endemismos en tres géneros. Los taxones endémicos ocupan dos de las regiones ecológicas, Bosque Húmedo Amazónico y Bosque Húmedo Premontano, entre los 180 y 1100 m de altitud. Dos de estos taxones endémicos se encuentran representados en áreas naturales protegidas.

  7. Rutaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Rutaceae es reconocida en el Perú por presentar 25 géneros y 76 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, principalmente árboles y arbustos. En este trabajo reconocemos seis endemismos, representando igual número de géneros. Los taxones endémicos se encuentran en las regiones Bosques Húmedos Amazónicos, Bosques Muy Húmedos Premontanos y Mesoandina, entre los 130 y 2000 m de altitud. Tres taxones se encuentran representados dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  8. Oleaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Isidoro Sánchez

    2013-10-01

    Full Text Available La familia Oleaceae es reconocida en el Perú por presentar seis géneros y 13 especies (Brako & Zarucchi, 1993, la mayoría árboles. En este trabajo reconocemos dos especies endémicas en igual número de géneros. Las especies endémicas han sido encontradas en las regiones Matorral Desértico y Bosques Húmedos Amazónicos, entre los 250 y 1850 m de altitud. Ambas especies se encuentran dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  9. Alternate day treatment and late effects: The concept of an effective dose per fraction

    International Nuclear Information System (INIS)

    Courdi, A.; Hery, M.; Gabillat, J.M.

    1990-01-01

    Although most institutions treat all fields each day, some radiotherapists continue to adopt an alternate day schedule. The resulting daily variations of the dose per fraction in laterally located targets have been analyzed using the linear-quadratic model. Patients with breast carcinoma treated with definitive radiotherapy in 1974-1975 with one field a day were studied. An effective dose per fraction was derived, with a value higher than the average dose per fraction received by the reference point. The greater the fluctuations between the doses per fraction on successive days, the higher the effective dose per fraction. The corresponding cell survival due to alternate treatment as compared to survival with daily treatment depends on the alpha/beta ratio. For a late effect with low alpha/beta ratio, an alternate treatment may lead to almost 10-fold increase in cell kill in these lateral targets such as those responsible for subcutaneous sclerosis as compared to daily treatment of all fields with the same total dose. Taking the average effective dose per fraction in our series, the increase in cell kill was 4-fold. Acute effects would suffer less damage due to alternate treatment because of a high alpha/beta ratio. Treatment on an alternate schedule should be restricted to palliative radiotherapy

  10. Skin reactions of rat feet exposed to multiple fractions of X rays per day

    International Nuclear Information System (INIS)

    Rongen, E. van

    1983-01-01

    The right hind feet of female WAG/Rij rats were irradiated with multiple fractions per day (4 x 2 Gy daily), with daily fractions of 3 Gy and with single doses of 300 kV X-rays. Acute reactions were scored 5 times per week until the reactions disappeared. Mean scores were derived from the 7-day period encompassing the peak reaction. The mean scores for the acute reactions are presented. Tolerance doses, defined as the total doses resulting in one small area of moist desquamation in 50% of the animals, as calculated by probit analysis are 55.7 +- 0.7 Gy for the 4 x 2 Gy per day scheme and 67.3 +- 2.9 Gy for the 3 Gy per day scheme. It can be seen that, when increasing the total dose above the tolerance dose, the mean reaction to the 3 Gy per day regimen reaches a plateau (corresponding to 10 to 40% moist desquamation of the sole of the foot), while the reaction to the 4 x 2 Gy per day regimen increases to the maximum, i.e., moist desquamation of the entire foot. These differences can be attributed to differences in repair of sublethal damage and repopulation. (Auth.)

  11. Predicting Good Features for Image Geo-Localization Using Per-Bundle VLAD (Open Access)

    Science.gov (United States)

    2016-02-18

    the database, we propose per -bundle vector of locally aggregated de- scriptors (PBVLAD), where each maximally stable region is described by a vector of...a large area. We propose a per -bundle vector of locally aggregated descriptors (PBVLAD) for fea- ture representation, where each maximally stable

  12. LHC Report: 1,033 bunches per beam and counting

    CERN Multimedia

    Jorg Wenninger for the LHC team

    2015-01-01

    Following the second technical stop, the first beams were injected into the LHC in the early evening of Saturday, 5 September. About ten days later, the machine was operated with around 1,000 bunches per beam.    Evolution of the stored energy per LHC beam, over time.   The first step after a technical stop consists of running through a full LHC cycle, from injection to collisions and beam dump, with a low-intensity bunch (“probe”) to check all machine settings and equipment. This is followed by a series of collimation and absorber validation tests at different points in the LHC cycle. Low-intensity beams – typically the equivalent of three nominal bunches (3 x 1011 protons) – are expanded transversely or longitudinally, or de-bunched to verify that the collimators and absorbers are correctly intercepting lost particles. The techniques for those validations have been progressively improved, and t...

  13. La politica ottimale per il Mezzogiorno:un commento a Moro

    Directory of Open Access Journals (Sweden)

    Bert Jossa

    2002-09-01

    Full Text Available In uno scritto recente ho sostenuto la tesi che la politica ottimale per il Mezzogiorno non è il laissez faire, né l’intervento diretto dello stato nell’economia, ma un intervento pubblico, anche “massiccio”, realizzato mediante leggi generali e astratte, che per loro natura sono di tipo non discrezionale.La necessità di un intervento generalizzato a favore di una zona meno sviluppata si giustifica con l’esistenza delle “diseconomie esterne”, che frenano lo sviluppo di tutte le imprese che operano in quella zona. Ha destato, perciò, in me meraviglia leggere l’articolo scritto contemporaneamente da Beniamino Moro (2001 e pubblicato nel numero 215 di questa rivista, che raggiunge lo stesso risultato con argomentazioni di segno opposto.

  14. 75 FR 52947 - Maximum Per Diem Rates for the Continental United States (CONUS)

    Science.gov (United States)

    2010-08-30

    ... per diem rate setting process enhances the government's ability to obtain policy-compliant lodging where it is needed. In conjunction with the annual lodging study, GSA identified five new non-standard... diem localities and updates the standard CONUS rate. The CONUS per diem rates prescribed in Bulletin 11...

  15. 47 CFR 22.507 - Number of transmitters per station.

    Science.gov (United States)

    2010-10-01

    ... those that operate together as a system (e.g., trunked systems, simulcast systems), rather than independently. (b) Split of large systems. The FCC may split wide-area systems into two or more stations for... PUBLIC MOBILE SERVICES Paging and Radiotelephone Service § 22.507 Number of transmitters per station...

  16. What Can We Learn from PER: Physics Education Research?

    Science.gov (United States)

    Singh, Chandralekha

    2014-01-01

    Physics Education Research (PER) focuses on understanding how students learn physics at all levels and developing strategies to help students with diverse prior preparations learn physics more effectively. New physics instructors are encouraged to visit http://PhysPort.org, a website devoted to helping instructors find effective teaching resources…

  17. Premature baby with extreme hyponatraemia (95 mmol per litre): a case report.

    Science.gov (United States)

    Abelian, Arthur; Ghinescu, Cristian Eugen

    2015-09-16

    Whilst mild neonatal hyponatraemia is common and relatively harmless, extreme hyponatraemia of 95 mmol per litre has never been reported in a premature baby and such a level could be associated with immediate as well as long-lasting detrimental effects on health. Twenty-four days old baby boy born at 28 weeks gestation (triplet one) unexpectedly became moribund with hypovolaemic shock and was found to have blood sodium of 95 mmol per litre. Diagnostic work up revealed a combination of a urinary tract infection, inadvertently low sodium provision with donor breast milk, and weak renin-angiotensin-aldosterone response. Commencement of treatment with intravenous fluids and extra sodium led to unanticipated diuresis and faster than expected increase of sodium level. Ultimately, treatment resulted in clinical recovery and normalisation of sodium level, which subsequently remained normal with no additional sodium supplementation. Follow up revealed mild spastic diplegia. Continuous monitoring and daily medical reviews may not be sensitive enough to recognise development of extreme hyponatraemia. Blood sodium levels should be monitored closely and any abnormalities promptly addressed. Treatment of hypovolaemic hyponatraemia should be centred on fluid resuscitation, anticipation of "paradoxical" diuresis, and blood sodium correction rate of 8 to 10 mmol per litre per day.

  18. Velocity of sound measurements in gaseous per-fluorocarbons and their custom mixtures

    CERN Document Server

    Vacek, V; Lindsay, S

    2000-01-01

    An inexpensive sonar instrument was prepared for measurements of sound velocity in two fluorocarbon vapors; per-fluoro-n-propane (C3F8), per-fluoro-n-butane (C4F10), and their custom mixtures. The apparatus, measurement principle and instrument software are described. All sound velocity measurements in per-fluorocarbons were made in the low pressure range between 0.01 and 0.4 MPa, and at temperatures between 253 and 303 K. The purity of the C3F8 and C4F10 samples was checked using gas chromatography. Uncertainties in the speed of sound measurements were better than ± 0.1 %. Comparisons were made with theoretical predictions of sound velocity for the two individual components. The instrument was then used for concentration monitoring of custom C3F8/C4F10 mixtures.

  19. A telemanipulator's direct manipulation interface; Interfaccia a manipolazione diretta per un telemanipolatore

    Energy Technology Data Exchange (ETDEWEB)

    Zirilli, P; Levialdi, S [Rome Univ. La Sapienza, Rome (Italy). Dipt. Scienze dell' Informazione; Manzano, J L [ENEA, Centro Ricerche Casaccia, S. Maria di Galeria, RM (Italy). Dipt. Innovazione

    1999-07-01

    The report discusses the analysis results of the interface of the ENEA's (National Agency for New Technology, Energy and the Enumerative) telemanipulator Mascot. A criterion to measure the u suability of an interface and a paradigm to manipulate objects in a virtual environment using devices without force feedback are proposed. A prototype for the Mascot's interface and a simulator of the telemanipulator are described. [Italian] Vengono presentati i risultati dell'analisi dell'interfaccia Mascot, un telemanipolatore sviluppato dall'ENEA. Si introduce un criterio di complessita' per misurare l'uso di un'interfaccia e si propone un paradigma per l'interazione con ambienti virtuali, applicabili alla manipolazione di oggetti tramite dispositivi che non forniscono controreazione di forza. Si descrive infine la realizzazione di un prototipo di un'interfaccia e di un simulatore per l'utilizzo del telemanipolatore.

  20. LOC2LOC : Desenvolupament d'aplicacions per a dispositius Android

    OpenAIRE

    Mendaño Montoro, David

    2016-01-01

    Aplicació per localitzar dispositius android i guardar i gestionar localitzacions. Android application to locate and manage and store locations. Aplicación para localizar dispositivos android y guardar y gestionar localizaciones.

  1. Aspectos ambientales de algunos ríos camaroneros del Perú

    OpenAIRE

    Llanos Urbina, Jorge

    1980-01-01

    Se presenta un estudio de las condiciories ambientales en cinco ríos camaroneros de la Costa Central y Sur del Perú, considerando la temperatura, la concentración de oxígeno disuelto, la alcalinidad total, el pH, la conductividad y la dureza del agua. Se menciona la existencia de otros factores como el período hidrológico y el tipo de fondo, como elementos importantes en relación con la vida del camarón. Se sugiere que existe una contaminación química potencial de todos los ríos estud...

  2. Planeamiento estratégico para el pimiento en el Perú

    OpenAIRE

    Coral Chávez, Ángela; Estrada Figueroa, Julio; Ruiz Huaringa, Katherine; Trisoglio Carrión, Renzo

    2017-01-01

    xxii, 189 h. : il. ; 30 cm. El objetivo de la presente investigación es realizar el Planeamiento Estratégico para el Pimiento en el Perú, el cual fue elaborado en función al Modelo Secuencial del Proceso Estratégico. Este modelo concluye con el Plan Estratégico Integral para el Pimiento en el Perú que incluye, entre otros, la misión, visión, estrategias externas específicas retenidas y objetivos de corto y largo plazo. El análisis de la investigación se centra en el Pimiento ...

  3. Planeamiento estratégico del café en el Perú

    OpenAIRE

    Ayala Gómez, Erika Jesús; Bernabé Ponte, Elí; Montoya Amemiya, Magally; Pinedo Gamarra, Joel Ángel

    2016-01-01

    El sector cafetalero peruano registró en los últimos años decrecimiento en la producción de granos de café a causa de la crisis generada por el virus de la roya el 2013, lo cual afectó la mayor parte de las plantaciones de cafeto y demostró que muchos de los productores no estaban debidamente capacitados para afrontarla. Sin embargo, el café del Perú ha sido reconocido como uno de los productos tradicionales más importantes que el Perú exporta, ello se ve reflejado en el aumento de su demanda...

  4. La ayuda oficial al desarrollo en salud en el Perú

    OpenAIRE

    Carlos Arósquipa; Julio Pedroza; Carlos Cosentino; Karim Pardo

    2007-01-01

    En este artículo se revisa la ayuda oficial al desarrollo a través de la cooperación internacional, particularmente en el campo de la salud, a nivel regional y en el Perú. Se describe como ha sido su evolución desde 1995, cuales son las fuentes cooperantes, que proyectos han sido y se están financiando así como las áreas que reciben mayor cooperación. Se hace un análisis de la experiencia obtenida por el Ministerio de Salud del Perú y cuales son las lecciones aprendidas. Finalmente se evalúan...

  5. PerMallows: An R Package for Mallows and Generalized Mallows Models

    Directory of Open Access Journals (Sweden)

    Ekhine Irurozki

    2016-08-01

    Full Text Available In this paper we present the R package PerMallows, which is a complete toolbox to work with permutations, distances and some of the most popular probability models for permutations: Mallows and the Generalized Mallows models. The Mallows model is an exponential location model, considered as analogous to the Gaussian distribution. It is based on the definition of a distance between permutations. The Generalized Mallows model is its best-known extension. The package includes functions for making inference, sampling and learning such distributions. The distances considered in PerMallows are Kendall's τ , Cayley, Hamming and Ulam.

  6. Plants arrangement and number of seeds per hole in the agroeconomic yield of pea

    Directory of Open Access Journals (Sweden)

    Elissandra Pacito Torales

    2014-12-01

    Full Text Available The aim of this work was to study the ‘luciana 50’ pea, cultivated with different numbers of rows of plants in the plot and with two and three seeds per hill. The work carried out in Dourados-MS, between March-July 2010. Treatments were arranged in 3 x 2 factorial in randomized complete block design with six replicates. Populations corresponding to the sowing with two, three and four rows per plot were 264,000, 396,000 and 528,000 plants ha-1, respectively, with two seeds per hill, and 396,000, 594,000 and 792,000 plants ha-1, respectively, with three seeds per hill. The harvest was done at 108 days after sowing. In cultivation with four rows of plants and two seeds per hill, were obtained the highest yields of fresh and dry weight of grains and pods commercial, with increases of 29.88%, 33.85%, 29.14% and 32.22%, respectively, and higher number of grains and pods commercial, with increases of 28.13% and 27.12%, respectively, over two rows of plants with two seeds per hill. The highest yield of fresh weight of shoots, of bark and of non-commercial pods were with four rows of plants, with increases of 1.75 t ha-1, 0.44 t ha-1 and 0.47 t ha-1 respectively, compared to two rows. Considering the yield of commercial pods and grains and the estimated net income, it can be concluded that sowing of ‘Luciana 50’ pea should be performed with four rows of plants and two seeds per hill.

  7. Non-selective regulation of peroxide and superoxide resistance genes by PerR in Campylobacter jejuni

    Directory of Open Access Journals (Sweden)

    Jong-Chul eKim

    2015-02-01

    Full Text Available Campylobacter jejuni is an important foodborne pathogen. The molecular mechanisms for the regulation of oxidative stress resistance have not yet been understood fully in this bacterium. In this study, we investigated how PerR (peroxide stress regulator modulates the transcriptional regulation of both peroxide and superoxide resistance genes in C. jejuni, particularly under oxidative stress conditions. The transcriptional levels of ahpC, katA, and sodB were substantially increased by aeration and oxidant exposure. Interestingly, a perR mutation completely abrogated the transcriptional response of ahpC, katA and sodB to oxidants. Furthermore, we demonstrated that perR transcription was reduced by aeration and oxidant exposure. In contrast to the unique role of PerR homologs in peroxide stress regulation in other bacteria, interestingly, C. jejuni PerR directly regulates the transcription of sodB, the most important gene in superoxide defense, as evidenced by the alteration of sodB transcription by the perR mutation and direct binding of rPerR to the sodB promoter. In addition, we also observed notable morphological changes in C. jejuni from spiral rods to coccoid morphology under aerobic conditions. Based on the intracellular ATP levels, C. jejuni entered a viable-but-non-culturable state under aerobic conditions. These findings clearly demonstrate that C. jejuni possesses a unique regulatory mechanism of oxidative stress defense that does not specifically distinguish between peroxide and superoxide defense, and PerR plays a pivotal role in this non-selective regulation of oxidative stress resistance in C. jejuni.

  8. Moraceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Pamela Cáceres

    2013-10-01

    Full Text Available La familia Moraceae es reconocida en el Perú por presentar 19 géneros y 128 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, la mayoría arbóreas y/o hemiepífitos. En este trabajo reconocemos dos especies endémicas en igual número de géneros. Las especies endémicas se encuentran en la región Bosques Húmedos Amazónicos, entre los 115 y 220 m de altitud. Ambas especies endémicas se encuentran dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  9. Rosaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Wilfredo Mendoza

    2013-10-01

    Full Text Available La familia Rosaceae es reconocida en el Perú por presentar 24 géneros y 113 especies (Brako & Zarucchi, 1993; Mendoza, 2005; Ulloa Ulloa et al., 2004, entre hierbas, arbustos y árboles. En este trabajo reconocemos 14 especies endémicas en cuatro géneros. Las especies endémicas se encuentran principalmente en las regiones Bosques Pluviales Montanos, Bosques Muy Húmedos Montanos y Páramo, entre los 1900 y 3800 m de altitud. Seis especies endémicas se encuentran representadas dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  10. Thelypteridaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available Esta familia es reconocida en el Perú con dos géneros y más de 100 especies (Smith, 1992; Smith et al., 2005, las que habitan un amplio rango de ambientes. Los endemismos en esta familia se hallan en el género Thelypteris con 17 endemismos. Con la excepción de una especie de la región Mesoandina, todas las especies endémicas ocupan las regiones de los Bosques Húmedos Montanos y Premontanos, entre los 400 y 3400 m de altitud. Ocho especies cuentan con poblaciones en áreas protegidas.

  11. Many multicenter trials had few events per center, requiring analysis via random-effects models or GEEs.

    Science.gov (United States)

    Kahan, Brennan C; Harhay, Michael O

    2015-12-01

    Adjustment for center in multicenter trials is recommended when there are between-center differences or when randomization has been stratified by center. However, common methods of analysis (such as fixed-effects, Mantel-Haenszel, or stratified Cox models) often require a large number of patients or events per center to perform well. We reviewed 206 multicenter randomized trials published in four general medical journals to assess the average number of patients and events per center and determine whether appropriate methods of analysis were used in trials with few patients or events per center. The median number of events per center/treatment arm combination for trials using a binary or survival outcome was 3 (interquartile range, 1-10). Sixteen percent of trials had less than 1 event per center/treatment combination, 50% fewer than 3, and 63% fewer than 5. Of the trials which adjusted for center using a method of analysis which requires a large number of events per center, 6% had less than 1 event per center-treatment combination, 25% fewer than 3, and 50% fewer than 5. Methods of analysis that allow for few events per center, such as random-effects models or generalized estimating equations (GEEs), were rarely used. Many multicenter trials contain few events per center. Adjustment for center using random-effects models or GEE with model-based (non-robust) standard errors may be beneficial in these scenarios. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. A hybrid study of multiple contributors to per capita household CO2 emissions (HCEs) in China.

    Science.gov (United States)

    Qu, Jiansheng; Qin, Shanshan; Liu, Lina; Zeng, Jingjing; Bian, Yue

    2016-04-01

    Given the large expenditures by households on goods and services that contribute a large proportion of global CO2 emissions, increasing attention has been paid to household CO2 emissions (HCEs). However, compared with industrial CO2 emissions, efforts devoted to mitigating HCEs are relatively small. A good understanding of the effects of some driving factors (i.e., urbanization rate, per capita GDP, per capita income/disposable income, Engel coefficient, new energy ratio, carbon intensity, and household size) is urgently needed prior to considering policies for reducing HCEs. Given this, in the study, the direct and indirect per capita HCEs were quantified in rural and urban areas of China over the period 2000-2012. Correlation analysis and gray correlation analysis were initially used to identify the prime drivers of per capita HCEs. Our results showed that per capita income/disposable income, per capita GDP, urbanization rate, and household size were the most significantly correlated with per capita HCEs in rural areas. Moreover, the conjoint effects of the potential driving factors on per capita HCEs were determined by performing principal component regression analysis for all cases. Based on the combined analysis strategies, alternative polices were also examined for controlling and mitigating HCEs growth in China.

  13. Ritorno alle cose, amore per le cose. Lo spazio etico della letteratura

    Directory of Open Access Journals (Sweden)

    Pino Menzio

    2014-07-01

    Full Text Available Di recente si è registrato, in ambito filosofico, un ritorno di interesse per l’oggettività. Le sue manifestazioni più significative si richiamano a due nuclei teorici fondamentali: l’attenzione per l’esperienza artistica e letteraria, e la convinzione che da essa derivi una precisa posizione etica. Ciò non accade nelle riprese del pensiero di Searle note come «nuovo realismo», il cui rapporto con la letteratura è particolarmente problematico.

  14. Sviluppo di metodi analitici per determinazioni affidabili in campo ambientale ed alimentare

    OpenAIRE

    Notardonato, Ivan

    2010-01-01

    La presenza di sostanze tossiche nei prodotti alimentari è stato da sempre un problema di grande rilevanza e influenza sociale sia per la natura sia per l’uomo. Nel corso degli anni sono state studiate e caratterizzate diverse sostanze presenti nell’ambiente, molte catalogate come tossiche, derivanti sia da fonti naturali sia da fonti industriali. Alcune di queste sostanze sono state ritenute particolarmente pericolose e quindi è nata l’esigenza di monitorarle e/o di cercare di limitarne il ...

  15. A radiotherapeutic clinical trial of twice per week vs. five times per week in oral cancer

    International Nuclear Information System (INIS)

    Handa, K.; Edoliya, T.N.; Pandey, R.P.; Agarwal, Y.C.; Sinha, N.

    1980-01-01

    135 cases of oral cancer have been treated by two fractions per week, and the results are compared with 115 approximately identical cases treated by conventional five days a week schedule with other parameters being identical. Radical irradiation was done by 6000 to 6500 rd in 6-6 1/2 weeks (NSD 1800-1900 ret) and palliative dose was 4500 R4 weeks (NSD 1532 ret). Tumour regression was found markedly superior by conventional regime in radically irradiated cases but much less superior for palliative treatment. Acute and late reaction as well as tumour control at 1 year was better with daily treatment, more so in cases treated for radical cure, while in palliative treatment, the superiority of daily regime was less marked. Our study provides evidence that only for palliation in advanced cases, radiation therapy by 2 fractions a week can be alternatively used. (orig.) [de

  16. USP2 Regulates the Intracellular Localization of PER1 and Circadian Gene Expression

    DEFF Research Database (Denmark)

    Yang, Yaoming; Duguay, David; Fahrenkrug, Jan

    2014-01-01

    . Although Per1 mRNA expression rhythm remained intact in the Usp2 KO MEFs, the expression profiles of other core clock genes were altered. This was also true for the expression of clock-controlled genes (e.g., Dbp, Tef, Hlf, E4bp4). A similar phase advance of PER1 nuclear localization rhythm and alteration...

  17. Sviluppi di Ricevitori E di Componentistica Per Banda 3 mm Ad INAF-OA Cagliari

    Science.gov (United States)

    Navarrini, Alessandro

    2017-11-01

    L'INAF-OA Cagliari (OACa) sta sviluppando un ricevitore criogenico a basso rumore basato su un mixer SSB (Single Side Band) a superconduttore SIS (Superconductor-Insulator-Superconductor) per la banda 3 mm. Il ricevitore, acquistato da IRAM, è stato fortemente modificato per essere adattato al fuoco Gregoriano di SRT (Sardinia Radio Telescope). Lo strumento è caratterizzato da una nuova criogenia a ciclo chiuso 4 K (per evitare l'uso di elio liquido in antenna), da un nuovo oscillatore locale (di tipo ALMA Banda 3) e da un nuovo sistema di controllo e di monitoraggio basato su schede Raspberry ed Arduino sviluppato ad OACa. Verranno presentati i recenti sviluppi sul ricevitore, inclusi i risultati preliminari della misura della temperatura di rumore, che raggiunge un valore pari a Trec=66 K alla frequenza di 86 GHz, nonostante la criogenia non sia ancora ottimizzata. L'INAF-OACa è coinvolto nel progetto AETHRA (Advanced European Technologies for Heterodyne Receivers for Astronomy) nel quadro del programma Radionet/Horizon2020 per il quale sta contribuendo al WP1 (Work Package 1). Lo scopo del WP1 è di sviluppare e costruire un dimostratore di un array di ricevitori a doppia polarizzazione per la banda 3 mm basato su amplificatori criogenici a basso rumore (LNA) in tecnologia a semiconduttore MMIC. Nell'ambito del WP1 l'OACa ha in carico il progetto di un OrthomodeTransducer (OMT) in guida d'onda o in tecnologia planare per la banda 72-116 GHz che sia integrabile con amplificatori MMICs ed adatto all'integrazione in un array da installare nel piano focale di un radiotelescopio. Verranno presentati i design preliminari degli OMT per AETHRA, che sono basati su prototipi sviluppati in passato da OACa.

  18. IgE-Binding Epitope Mapping and Tissue Localization of the Major American Cockroach Allergen Per a 2.

    Science.gov (United States)

    Lee, Mey Fann; Chang, Chia Wei; Song, Pei Pong; Hwang, Guang Yuh; Lin, Shyh Jye; Chen, Yi Hsing

    2015-07-01

    Cockroaches are the second leading allergen in Taiwan. Sensitization to Per a 2, the major American cockroach allergen, correlates with clinical severity among patients with airway allergy, but there is limited information on IgE epitopes and tissue localization of Per a 2. This study aimed to identify Per a 2 linear IgE-binding epitopes and its distribution in the body of a cockroach. The cDNA of Per a 2 was used as a template and combined with oligonucleotide primers specific to the target areas with appropriate restriction enzyme sites. Eleven overlapping fragments of Per a 2 covering the whole allergen molecule, except 20 residues of signal peptide, were generated by PCR. Mature Per a 2 and overlapping deletion mutants were affinity-purified and assayed for IgE reactivity by immunoblotting. Three synthetic peptides comprising the B cell epitopes were evaluated by direct binding ELISA. Rabbit anti-Per a 2 antibody was used for immunohistochemistry. Human linear IgE-binding epitopes of Per a 2 were located at the amino acid sequences 57-86, 200-211, and 299-309. There was positive IgE binding to 10 tested Per a 2-allergic sera in 3 synthetic peptides, but none in the controls. Immunostaining revealed that Per a 2 was localized partly in the mouth and midgut of the cockroach, with the most intense staining observed in the hindgut, suggesting that the Per a 2 allergen might be excreted through the feces. Information on the IgE-binding epitope of Per a 2 may be used for designing more specific diagnostic and therapeutic approaches to cockroach allergy.

  19. Distribution and Analysis of Heavy Metals Contamination in Soil, Perlis, Malaysia

    Science.gov (United States)

    Nihla Kamarudzaman, Ain; Woo, Yee Shan; Jalil, Mohd Faizal Ab

    2018-03-01

    The concentration of six heavy metals such as Cu, Cr, Ni, Cd, Zn and Mn were studied in the soils around Perlis. The aim of the study is to assess the heavy metals contamination distribution due to industrialisation and agricultural activities. Soil samples were collected at depth of 0 - 15 cm in five stations around Perlis. The soil samples are subjected to soil extraction and the concentration of heavy metals was determined via ICP - OES. Overall concentrations of Cr, Cu, Zn, Ni, Cd and Mn in the soil samples ranged from 0.003 - 0.235 mg/L, 0.08 - 41.187 mg/L, 0.065 - 45.395 mg/L, 0.031 - 2.198 mg/L, 0.01 - 0.174 mg/L and 0.165 - 63.789 mg/L respectively. The concentration of heavy metals in the soil showed the following decreasing trend, Mn > Zn > Cu > Ni > Cr > Cd. From the result, the level of heavy metals in the soil near centralised Chuping industrial areas gives maximum value compared to other locations in Perlis. As a conclusion, increasing anthropogenic activities have influenced the environment, especially in increasing the pollution loading.

  20. Vertebrados naturalizados en el Perú: historia y estado del conocimiento

    Directory of Open Access Journals (Sweden)

    E. Daniel Cossíos

    2011-05-01

    Full Text Available A pesar de la importancia de los impactos de las especies exóticas sobre la biodiversidad nativa, éstas han sido poco estudiadas en Sudamérica. En el Perú, la información publicada sobre el tema es rara y se encuentra muchas veces restringida a publicaciones poco conocidas, lo que dificulta el análisis del problema y la toma de decisiones para su manejo. En esta publicación se identifica 23 especies de vertebrados naturalizados en el Perú y se resume la información conocida sobre su dispersión en el país, distribución actual e impactos sobre ambientes naturales. Asimismo, se identifica 8 especies que fueron objeto de intentos fallidos de introducción a ambientes naturales o cuyas poblaciones naturalizadas se extinguieron y 10 especies de vertebrados cuya naturalización es probable pero debería ser verificada. Esta información debería servir de base para la creación de un plan de investigación sobre las especies naturalizadas en el Perú y sus impactos.

  1. Computer-Aided Construction at Designing Reinforced Concrete Columns as Per Ec

    Science.gov (United States)

    Zielińska, M.; Grębowski, K.

    2015-02-01

    The article presents the authors' computer program for designing and dimensioning columns in reinforced concrete structures taking into account phenomena affecting their behaviour and information referring to design as per EC. The computer program was developed with the use of C++ programming language. The program guides the user through particular dimensioning stages: from introducing basic data such as dimensions, concrete class, reinforcing steel class and forces affecting the column, through calculating the creep coefficient taking into account the impact of imperfection depending on the support scheme and also the number of mating members at load shit, buckling length, to generating the interaction curve graph. The final result of calculations provides two dependence points calculated as per methods of nominal stiffness and nominal curvature. The location of those points relative to the limit curve determines whether the column load capacity is assured or has been exceeded. The content of the study describes in detail the operation of the computer program and the methodology and phenomena which are indispensable at designing axially and eccentrically the compressed members of reinforced concrete structures as per the European standards.

  2. Southern Perú coseismic subsidence: 23 June 2001 8.4-Mw earthquake

    Directory of Open Access Journals (Sweden)

    L. Ocola

    2008-01-01

    Full Text Available The 23-June-2001 8.4-Mw magnitude earthquake partially filled the 1868-seismic-gap in southern Perú. This earthquake produced a thrust faulting dislocation with a rupture that started at about ~200 km SE from the 1996's Nazca earthquake epicenter, and stopped near Ilo, at about 300 km from the epicenter, near a positive gravity anomaly offshore Ilo. The 23-June-2001-earthquake dislocation zone is under the Arequipa sedimentary Basin. Pre- and post-seismic GPS measurements at Camaná and Ilo at SIRGAS-GPS points (SIRGAS: Sistema de Referencia Geocéntrico para América del Sur and the average sea level pre- and post-seismic event at Mollendo tide gauge provide evidence of a regional subsidence of southern Perú, with 84 cm at Camaná, 16 cm at Ilo, and 15 cm at Mollendo. Field surveys post earthquake document significant subsidence in Camaná resort beaches. Results of a simple dislocation modelling of 23-June-2001 earthquake agree reasonably well with the observed data. However, the coseismic subsidence of southern Perú is at variance with the regional uplift of southern Perú based on Neotectonic studies. This fact, suggests that, in recent geological times, the magnitude of the secular uplift due to tectonic plate converge has been larger than the coseismic deformation recovery.

  3. La iniciativa de vivienda saludable en el Perú

    Directory of Open Access Journals (Sweden)

    Rosario Santa María

    2008-10-01

    Full Text Available El objetivo del presente documento es identificar los principales indicadores relacionados con la salud de las familias en su domicilio y peridomicilio y, de tal manera, comprender la importancia de difundir en nuestro país la Iniciativa de Vivienda Saludable promovida por la Organización Panamericana de la Salud. Nos hemos focalizado en los factores de salud relacionados con la vivienda en las diferentes regiones del Perú, teniendo en cuenta las formas de vida locales, priorizando el análisis en los sectores socio-económicos de menores ingresos de las ciudades y con la consideración de que el tema de la vivienda saludable es un componente importante dentro de la salud ambiental. El contenido es resultado de entrevistas a profesionales con experiencia en los temas de salud y vivienda, así como contrastar información bibliográfica y periodística con nuestra apreciación subjetiva de la realidad, para llegar a conclusiones y recomendaciones generales. Ante las condiciones de la vivienda en el Perú y sus repercusiones en la salud de la población, se hizo necesario favorecer la conformación de una red nacional que agrupe a diversas instituciones públicas y privadas que vienen promoviendo en el Perú, desde diversos enfoques, el mejoramiento de las condiciones de la vivienda y de su entorno, con el propósito de complementar sus capacidades y apoyarse mutuamente en sus desempeños. Finalmente, consideramos que la vivienda saludable es un derecho y deber de las personas, en sintonía con el derecho a la salud y a la vida y la corresponsabilidad entre gobierno local y ciudadanía.

  4. CALiPER Special Summary Report: Retail Replacement Lamp Testing

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-04-01

    CALiPER testing has evaluated many products for commercial lighting markets and found some excellent performers. However, many of these are not available on the retail market. This special testing was undertaken to identify and test solid-state lighting (SSL) replacement lamp products that are available to the general public through retail stores and websites.

  5. Elementi di interfaccia per l’analisi di strutture murarie

    Directory of Open Access Journals (Sweden)

    Jessica Toti

    2009-04-01

    Full Text Available Il presente articolo riguarda la modellazione del comportamento meccanico di elementi in muratura intesi come sistemi eterogenei composti da malta, blocchi ed interfacce di connessione. La strategiacomputazionale che viene adottata consiste nel modellare separatamente i blocchi, i letti di malta ed le interfacce responsabili di fenomeni di decoesione malta-blocco; a tale scopo, si propone uno speciale modello di interfaccia che combina il danneggiamento con l’attrito. Si sviluppa una procedura numerica, basata sull’algoritmo backward di Eulero, per risolvere il problema evolutivo; per il passo temporale si utilizza invece la tecnica predictor-corrector a controllo di spostamenti. Si effettuano alcune applicazioni numeriche con lo scopodi verificare la capacità del modello e dell’algoritmo proposto nel riprodurre la risposta non lineare della muratura dovuta a fenomeni di degrado localizzati. Infine, si conduce lo studio della modellazione di un arco murario, confrontando i risultati numerici con quelli sperimentali; si dimostra la abilità del modello proposto nel simulare il comportamento globale della struttura ad arco in termini di carico ultimo e di meccanismo di collasso.

  6. Analysis and Pollution Assessment of Heavy Metal in Soil, Perlis

    International Nuclear Information System (INIS)

    Siti Norbaya Mat Ripin; Siti Norbaya Mat Ripin; Sharizal Hasan; Mohd Lias Kamal; NorShahrizan Mohd Hashim

    2014-01-01

    Concentration of 5 heavy metals (Cu, Cr, Ni, Cd, Pb) were studied in the soils around Perlis, to assess heavy metals contamination distribution due to industrialization, urbanization and agricultural activities. Soil samples were collected at depth of 0-15 cm in eighteen station around Perlis. The soil samples (2 mm) were obtained duplicates and subjected to hot block digestion and the concentration of total metal was determined via ICP-MS. Overall concentrations of Cu, Cr, Ni, Cd and Pb in the soil samples ranged from 0.38-240.59, 0.642-3.921, 0.689-2.398, 0-0.63 and 0.39-27.47 mg/ kg respectively. The concentration of heavy metals in the soil display the following decreasing trend: Cu> Pb> Cr> Ni> Cd. From this result, found that level of heavy metal in soil near centralized Chuping industrial areas give maximum value compared with other location in Perlis. The Pollution index revealed that only 11 % of Cu and 6 % of Cd were classes as heavily contaminated. Meanwhile, Cu and Pb showed 6 % from all samples result a moderately contaminated and the others element give low contamination. Results of combined heavy metal concentration and heavy metal assessment indicate that industrial activities and traffic emission represent most important sources for Cu, Cd and Pb whereas Cr, Ni mainly from natural sources. Increasing anthropogenic influences on the environment, especially pollution loadings, have caused negative changes in natural ecosystems and decreased biodiversity. (author)

  7. Rappresentazioni digitali al tratto: tecniche visuali per un utilizzo avanzato del CAD

    Directory of Open Access Journals (Sweden)

    Simone Garagnani

    2006-12-01

    Full Text Available Il vasto panorama esistente di prodotti software destinati al mondo del disegno architettonico, rischia di compromettere quell'individualità che distingue lo stile di rappresentazione del progettista puro. La consuetudine moderna alla rappresentazione tridimensionale fotorealistica a tutti i costi, dove tessiture di materiali e contrasti di luci ed ombre sono a volte talmente esasperati da avere ben poco del fotografico, ha condotto a trascurare le più tradizionali visualizzazioni al tratto, ancora importanti per la loro intrinseca chiarezza esplicativa e visuale delle forme. Non sono pochi infatti i software di nuova produzione che implementano con discutibile disinvoltura motori di rendering più o meno realistici, ma che non sono in grado di presentare disegni prospettici od assonometrici formalmente corretti e gradevoli. Il tracciamento assistito tuttavia può essere un valido strumento di sviluppo anche per tecniche visuali più classiche; in questo breve scritto verranno analizzati due metodi per ottenere questo tipo di elaborati con un pacchetto di disegno digitale standard come AutoCAD.

  8. Energy System Analysis of 100 Per cent Renewable Energy Systems

    DEFF Research Database (Denmark)

    Lund, Henrik; Mathiesen, Brian Vad

    2007-01-01

    This paper presents the methodology and results of the overall energy system analysis of a 100 per cent renewable energy system. The input for the systems is the result of a project of the Danish Association of Engineers, in which 1600 participants during more than 40 seminars discussed...... and designed a model for the future energy system of Denmark, putting emphasis on energy efficiency, CO2 reduction, and industrial development. The energy system analysis methodology includes hour by hour computer simulations leading to the design of flexible energy systems with the ability to balance...... the electricity supply and demand and to exchange electricity productions on the international electricity markets. The results are detailed system designs and energy balances for two energy target years: year 2050 with 100 per cent renewable energy from biomass and combinations of wind, wave and solar power...

  9. Is energy consumption per capita broken stationary? New evidence from regional-based panels

    International Nuclear Information System (INIS)

    Chen, P.-F.; Lee, C.-C.

    2007-01-01

    For the first time, a new panel unit root testing procedure, developed by [51]Carrion-i-Silvestre et al. [2005. Breaking the panels: an application to GDP per capita. Econometrics Journal 8, 159-175], is applied to re-investigate the stationarity of energy consumption per capita for 7 regional panel sets covering the 1971-2002 period. With structural breaks and cross-sectional correlations introduced into the model, it becomes clear that all regional-based panels of energy consumption per capita are stationary. The structural breakpoints identify the likely causes of major changes in energy consumption in the past. The findings underscore the importance of accounting for exogenous shocks to a series and offer several important implications for policy makers and energy economists

  10. Environmental analysis applied to schools. Methodologies for data acquisition; Analisi ambientale iniziale per gli istituti d'istruzione. Metodologia per l'acquisizione dei dati

    Energy Technology Data Exchange (ETDEWEB)

    Andriola, L; Ceccacci, R [ENEA, Div. Caratterizzazione dell' Ambiente e del Territorio, Centro Ricerche Casaccia, Rome (Italy)

    2001-07-01

    The environment analysis is the basis of environmental management for organizations and it is considered as the first step in EMAS. It allows to identify, deal with the issues and have a clear knowledge on environmental performances of organizations. Schools can be included in the organizations. Nevertheless, the complexity of environmental issues and applicable regulations makes very difficult for a school, that wants to implement an environmental management system (EMAS, ISO 14001, etc.), to face this first step. So, it has been defined an instrument, that is easy but complete and coherent with reference standard, to let schools choose their process for elaborating the initial environmental revue. This instrument consists, essentially, in cards that, if completed, facilitate the drafting of the environmental analysis report. [Italian] L'analisi ambientale iniziale costituisce il presupposto di qualsiasi azione di gestione ambientale da parte di un'organizzazione ed e' esplicitamente prevista, come prima tappa, in EMAS. Essa consente infatti di individuare ed approfondire le problematiche ambientali e di fotografare, per mezzo di riferimenti oggettivi, le prestazioni ambientali di un'organizzazione, e quindi anche di una scuola, in modo da poter stabilire e controllare nel tempo gli obiettivi di miglioramento. Tuttavia la complessita' delle problematiche ambientali e delle relative normative di riferimento rende estremamente difficoltoso, per un istituto scolastico che intenda intraprendere un percorso di gestione ambientale comunque finalizzato (EMAS, ISO 14001, Comunicazione ambientale, ecc.) compiere questo passo iniziale. E' stato pertanto realizzato uno strumento semplificato, ma comunque completo e coerente con gli standard di riferimento, per consentire alle scuole di effettuare il percorso di elaborazione di un'analisi ambientale iniziale. Lo strumento consiste essenzialmente in schede che, una volta compilate, faciliteranno la stesura del rapporto di

  11. Benefits and drawbacks of per diems: Do allowances distort good governance in the health sector?

    OpenAIRE

    Vian, Taryn

    2009-01-01

    Per diems, or daily allowances, are an important mechanism for reimbursing work‑related expenses, encouraging participation in professional development activities, and motivating under‑paid employees. Yet, sometimes employees may abuse per diem policies by falsifying travel reports or inflating workshop budgets for private gain. In addition, the possibility of earning per diem can have a distorting impact on programme design, management decisions, and how employees spend their time. Drawing o...

  12. Charge collection efficiency in ionization chambers exposed to electron beams with high dose per pulse

    Energy Technology Data Exchange (ETDEWEB)

    Laitano, R F [Istituto Nazionale di Metrologia delle Radiazioni Ionizzanti, ENEA Centro Ricerche Casaccia, c.p. 2400 Rome (Italy); Guerra, A S [Istituto Nazionale di Metrologia delle Radiazioni Ionizzanti, ENEA Centro Ricerche Casaccia, c.p. 2400 Rome (Italy); Pimpinella, M [Istituto Nazionale di Metrologia delle Radiazioni Ionizzanti, ENEA Centro Ricerche Casaccia, c.p. 2400 Rome (Italy); Caporali, C [Istituto Nazionale di Metrologia delle Radiazioni Ionizzanti, ENEA Centro Ricerche Casaccia, c.p. 2400 Rome (Italy); Petrucci, A [A.C.O. S. Filippo Neri, U.O. Fisica Sanitaria, Rome (Italy)

    2006-12-21

    The correction for charge recombination was determined for different plane-parallel ionization chambers exposed to clinical electron beams with low and high dose per pulse, respectively. The electron energy was nearly the same (about 7 and 9 MeV) for any of the beams used. Boag's two-voltage analysis (TVA) was used to determine the correction for ion losses, k{sub s}, relevant to each chamber considered. The presence of free electrons in the air of the chamber cavity was accounted for in determining k{sub s} by TVA. The determination of k{sub s} was made on the basis of the models for ion recombination proposed in past years by Boag, Hochhaeuser and Balk to account for the presence of free electrons. The absorbed dose measurements in both low-dose-per-pulse (less than 0.3 mGy per pulse) and high-dose-per-pulse (20-120 mGy per pulse range) electron beams were compared with ferrous sulphate chemical dosimetry, a method independent of the dose per pulse. The results of the comparison support the conclusion that one of the models is more adequate to correct for ion recombination, even in high-dose-per-pulse conditions, provided that the fraction of free electrons is properly assessed. In this respect the drift velocity and the time constant for attachment of electrons in the air of the chamber cavity are rather critical parameters because of their dependence on chamber dimensions and operational conditions. Finally, a determination of the factor k{sub s} was also made by zero extrapolation of the 1/Q versus 1/V saturation curves, leading to the conclusion that this method does not provide consistent results in high-dose-per-pulse beams.

  13. Cuscutaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Cuscutaceae es reconocida en el Perú por presentar un género, Cuscuta, y 19 especies (Brako & Zarucchi, 1993, todas ellas hierbas. En este trabajo reconocemos siete especies endémicas, aunque en necesidad de revisión taxonómica y colecciones botánicas; por ello no se aplicaron las categorías y criterios de la UICN. Estos taxones endémicos ocupan principalmente la región Mesoandina, por debajo de los 3200 m de altitud. Aparentemente, sólo una de estas especies se encuentra representada dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  14. Dilleniaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Dilleniaceae es una adición reciente a la flora endémica peruana; los endemismos han sido recolectados y reconocidos hacia fines de los 1990. Está representada en el Perú por seis géneros y 23 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, la mayoría lianas. En este trabajo reconocemos tres endemismos en dos géneros. Las especies endémicas ocupan la región Bosques Húmedos Amazónicos, entre los 100 y 125 m de altitud. No se encuentra representada en el Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  15. Onagraceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Susy Castillo

    2013-10-01

    Full Text Available Esta es la familia de las «fucsias», la cual es reconocida en el Perú por presentar seis géneros y 76 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, principalmente arbustos y hierbas. En este trabajo reconocemos 24 especies endémicas, la mayoría en el género Fuchsia. Las especies endémicas se encuentran mayormente en la región Bosques Muy Húmedos Montanos, entre los 1600 y 2500 m de altitud. Diez especies endémicas se encuentran representados dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  16. IMPACT OF INFLATION ON PER CAPITA INCOME IN EMERGING ECONOMIES: EVIDENCE FROM BRICS NATIONS

    Directory of Open Access Journals (Sweden)

    Khalid Ashraf CHISTI

    2015-12-01

    Full Text Available In this paper an attempt has been made to analyse the impact of Inflation on per capita income of emerging economies. In order to achieve the objective of the study the researchers have taken five major emerging countries of the world which are the members of BRICS. For the purpose of analysis, the data of thirteen years has been taken from 1999 to 2011. After employing the regression model, the results confirm that independent variable (inflation does not statistically influence the dependent variable (Per Capita Income in three countries which are India, Brazil and South Africa. However, in the other two countries (China and Russia the findings affirm the independent variable (Inflation does statistically influence the dependent variable (Per Capita Income.Therefore, it can be concluded that a change in the inflation rate can not necessarily bring a change in the per capita income of a country.

  17. Un corrector gramatical basat en cerques per Internet

    Directory of Open Access Journals (Sweden)

    Joaquim Moré

    2006-05-01

    Full Text Available En aquest article presentem un corrector gramatical de l'anglès destinat a escriptors no angloparlants. La principal característica d'aquest corrector és l'ús d'un motor de cerca per Internet. Com que hi ha un gran nombre de pàgines web escrites en anglès, el sistema fa la hipòtesi que un segment de text que no és present en cap pàgina web és probablement un segment de text mal escrit. El sistema també fa la hipòtesi que a la Xarxa hi trobarà exemples que ensenyaran a l'usuari com ha d'expressar el contingut del segment de text d'una manera gramatical i idiomàtica. Per tant, un cop el corrector avisa l'usuari que és millor verificar un segment del seu text, el motor cerca contextos que poden ser útils a la persona que escriu a l'hora de decidir si corregeix el segment o no. Gràcies també a l'ús d'un motor de cerca, el corrector suggereix a l'escriptor que utilitzi expressions que són més freqüents a la Xarxa en comptes de l'expressió que ha escrit. Text complet (PDF

  18. Diciotto uova per una crème caramel. La telepolitica come socievolezza

    OpenAIRE

    Nedelmann, Birgitta

    2017-01-01

    1. Introduzione All’inizio di settembre 1996 il radio-giornale informava la nazione tedesca che «il cancelliere Kohl usa diciotto uova per una crème caramel». Era una informazione tratta da un talkshow con il cancelliere, diretto da Alfred Biolek, conosciuto al pubblico tedesco anche per la sua capacità di cuoco televisivo, e trasmesso nel primo programma della televisione tedesca pochi giorni dopo, l’11 settembre 1996. L’intervista faceva scandalo in Germania. Ma non era il cancelliere a com...

  19. Producció audiovisual per a un centre mèdic

    OpenAIRE

    Núñez Pardo, Rafaela

    2014-01-01

    Creació d'uns clips de vídeo promocionals per a un centre d'ortopodologia. Creación de unos clips de vídeo promocionales para un centro de ortopodología. Bachelor thesis for the Multimedia program.

  20. The ADEME has been cautious by not publishing its '100 per cent renewable in 2050' scenario - Towards a 100 per cent renewable energy mix in 2050 - Final report

    International Nuclear Information System (INIS)

    Tamain, Bernard; Nifenecker, Herve; Fournie, Laurent; Chiche, Alice; Faure, Nathalie; Bardet, Regis; Alais, Jean-Christophe; Girard, Robin; Bossavy, Arthur; Le Gars, Loic; Biau, Jean-Baptiste; Piqueras, Ugo; Peyrusse, Colombe

    2015-01-01

    In a recent study which has not been published but could have been read by the authors, the ADEME tries to establish that, in 2050, it will be possible, in the sector of electricity production, to do without fossil and nuclear energies, and indicates that such a solution based on 100 per cent of renewable energies is economically viable. In this paper, the authors show that the renewable costs indicated by the ADEME in its '100 per cent renewable' scenario are significantly underestimated. They more precisely discuss the costs of roof-mounted or ground-based photovoltaic energy, ground-based and offshore wind energy, and of energy storage. They discuss issues related to grids, to intermittency management which they consider as an underestimated issue (constraints, imports, electric consumption, storage issues are addressed). The text of the ADEME study is also provided. This study aims at identifying the constraints under which it is possible to provide a 100 per cent renewable electricity, at determining the optimal energy mixes associated with different predictions of technological evolutions, consumption, and so on, at identifying the geographical distribution of the different renewable production means, and at determining the economic impacts of a 100 per cent renewable mix

  1. Anaerobic digestion of industrial hemp-effect of harvest time on methane energy yield per hectare

    Energy Technology Data Exchange (ETDEWEB)

    Kreuger, E; Escobar, F; Bjoernsson, L [Department of Biotechnology, Lund University, P.O. Box 124, SE-221 00 Lund (Sweden); Prade, T; Svensson, S -E; Englund, J -E [Department of Agriculture-Farming Systems, Technology and Product Quality, Swedish University of Agricultural Sciences, P.O. Box 104, SE-230 53 Alnarp (Sweden)

    2011-02-15

    There is a worldwide emphasis to increase the share of renewable transportation fuels. When using agricultural land for production of renewable transportation fuels, the energy output per hectare for different crops and transportation fuels is a crucial factor. In this study, the gross methane energy yield per hectare from anaerobic digestion of industrial hemp (Cannabis sativa L.), was determined at four different harvest times between July and October in Southern Sweden, a cold climate region. The biomass yield was determined for three years and the methane yield was determined for two years through the biochemical methane potential test. The highest biomass yield, 16 tonnes dry matter per hectare on an average, and the highest methane energy yield per hectare was achieved when the hemp was harvested in September or October, with an average gross methane energy yield of 136 {+-} 24 GJ per hectare. There was no significant difference in the specific methane yield between the harvest times; the average being 234 {+-} 35 m{sup 3} per tonne volatile solids. Biogas from hemp turned out to be a high yielding alternative to the currently dominating renewable transportation fuels produced from crops grown in Sweden: ethanol from wheat and biodiesel from rapeseed. (author)

  2. Bounding the per-protocol effect in randomized trials: An application to colorectal cancer screening

    NARCIS (Netherlands)

    S.A. Swanson (Sonja); Holme (Øyvind); M. Løberg (Magnus); M. Kalager (Mette); M. Bretthauer (Michael); G. Hoff (G.); E. Aas (Eline); M.A. Hernán (M.)

    2015-01-01

    textabstractBackground: The per-protocol effect is the effect that would have been observed in a randomized trial had everybody followed the protocol. Though obtaining a valid point estimate for the per-protocol effect requires assumptions that are unverifiable and often implausible, lower and upper

  3. La dottrina degli avatara come prova per la datazione dell’Abhinayadarpana di Nandikesvara

    Directory of Open Access Journals (Sweden)

    Pietro Chierichetti

    2012-01-01

    Full Text Available Abstract - IT Come per molte opere della letteratura indiana in sanscrito, anche per l’Abhinayadarpana di Nandikesvara è difficile proporre una datazione attendibile: nel suo contributo, l’autore cerca di utilizzare un elemento interno al testo per ipotizzare il periodo nel quale il testo potrebbe collocarsi. La citazione degli avatara di Visnu, esemplificata attraverso una serie di gesti delle mani, viene vagliata criticamente al fine di un suo possibile utilizzo per collocare l’opera dal punto di vista cronologico. L’Abhinayadarpana, uno dei test fondamentali del teatro-danza in India, viene in questo modo inserito nel panorama più ampio della vicenda religiosa dell’India antica e la storia della religione hindu fornisce a sua volta uno strumento interessante per la ricostruzione della storia del testo. Abstract - EN As it often happens for many works of the Indian literature in Sanskrit, it is difficult to determine a possible dating of Nandikesvara’s iAbhinayadarpana: in his article, the author tries to assume an inner element of the text for a hypothesis about the period in which the work could be dated back to. The Visnu’s avataras, quoted in the text through a series of hand gestures, are scientifcally examined to define the work from a chronological point of view. The Abhinayadarpana, one of the most important texts of the Indian Dance-Theatre, is put in the broader landscape of the Indian ancient religion and the hindu religion history becomes an interesting tool through which the text’s history is reconstructed.

  4. The Films at the Wake. Per un catalogo

    OpenAIRE

    Rinaldi, Rinaldo

    2014-01-01

    L'importanza del cinema nell'opera di James Joyce è stata più volte sottolineata dalla critica, soprattutto negli ultimi anni: pensiamo al ruolo suggestivo delle tecniche cinematografiche, ma anche all'ampio repertorio dei film che lo scrittore irlandese mostra di conoscere per passione di cinefilo. Meno studiato da questo punto di vista è Finnegans Wake. Il presente repertorio è dedicato alla presenza del cinema e dei film (ma anche dei registi e degli attori) nell'ultimo romanzo joyciano: c...

  5. Studio del comportamento di agenti di contrasto in campi ultracustici per tecniche di ecografia diagnostica

    OpenAIRE

    BIAGIONI, ANGELO

    2011-01-01

    Il presente lavoro di ricerca è stato articolato intorno a temi attinenti l’ingegneria biomedica, riguardando, in particolare, lo studio del comportamento di agenti di contrasto in campi ultracustici per tecniche di ecografia diagnostica. Nell’ambito di tale settore scientifico, un ruolo di fondamentale importanza è svolto dalla diagnostica medica per immagini e in particolare dalle tecniche ecografiche. Queste ultime rappresentano un ottimo compromesso tra la pericolosità per l’organismo e l...

  6. Evaluation of Instrumentation for Measuring Undissolved Water in Aviation Turbine Fuels per ASTM D3240

    Science.gov (United States)

    2015-11-05

    Undissolved Water in Aviation Turbine Fuels per ASTM D3240 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Joel Schmitigal... water ) in Aviation Turbine Fuels per ASTM D3240 15. SUBJECT TERMS fuel, JP-8, aviation fuel, contamination, free water , undissolved water , Aqua-Glo 16...Michigan 48397-5000 Evaluation of Instrumentation for Measuring Undissolved Water in Aviation Turbine Fuels per ASTM D3240 Joel Schmitigal Force

  7. Proposta d'ús de realitat augmentada per a aplicació comercial en catàlegs corporatius

    OpenAIRE

    Losada Sanjuán, Gregor

    2017-01-01

    El present projecte busca aplicar funcions de realitat augmentada en catàlegs comercials d'una companyia real. Es pretén donar més màrqueting als catàlegs augmentant l'apreciació de l'empresa coma referent tecnològic punter en el seu camp. Per a realitzar el projecte s'utilitzarà principalment tecnologia Unity per a configurar l'entorn tridimensional i programar les aplicacions, l'API de Vuforia per a gestionar els marcadors que s'utilitzaran per fixar els elements virtuals, 3DS Max ...

  8. Using data on resistance prevalence per sample in the surveillance of antimicrobial resistance

    DEFF Research Database (Denmark)

    Vieira, Antonio; Shuyu, Wu; Jensen, Lars Bogø

    2008-01-01

    Objectives: In most existing antimicrobial resistance monitoring programmes, one single bacterial colony from each collected sample is susceptibility tested against a panel of antimicrobials. Detecting the proportion of colonies resistant to different antimicrobials in each sample can provide...... quantitative data on antimicrobial resistance (resistance prevalence per sample). Methods: In this study, a total of 98 faecal samples from slaughter pigs were tested for tetracycline and sulphonamide resistance in Escherichia coli using the single colony method, and these results were compared...... with the results obtained using the resistance prevalence per sample method. Results: The results obtained by the resistance prevalence per sample method showed a lower occurrence of resistance. Tetracycline resistance in E. coli was found in 36.7% of the samples using the single colony method, while the mean...

  9. the demand for kerosene and per capita income in ethiopia

    African Journals Online (AJOL)

    RYilma

    and excellent weather outturn in much of the post-reform period (see Alemayehu. 2005) ... capita income growth to the tune of about 3% per annum. For an .... those attributes – rather than by correlates – the share of total inequality attributed to.

  10. Seasonal abundance, distribution and catch per unit effort of fishes ...

    African Journals Online (AJOL)

    included a note on the ecology of the estuary and Hanekom. (1982) has completed a ... Catch per unit effort (CPUE) of fish in the Krom estuary was obtained by means ...... Structural and functional aspects of the surf-zone fish community in the ...

  11. Factors Affecting Regional Per-Capita Carbon Emissions in China Based on an LMDI Factor Decomposition Model

    Science.gov (United States)

    Dong, Feng; Long, Ruyin; Chen, Hong; Li, Xiaohui; Yang, Qingliang

    2013-01-01

    China is considered to be the main carbon producer in the world. The per-capita carbon emissions indicator is an important measure of the regional carbon emissions situation. This study used the LMDI factor decomposition model–panel co-integration test two-step method to analyze the factors that affect per-capita carbon emissions. The main results are as follows. (1) During 1997, Eastern China, Central China, and Western China ranked first, second, and third in the per-capita carbon emissions, while in 2009 the pecking order changed to Eastern China, Western China, and Central China. (2) According to the LMDI decomposition results, the key driver boosting the per-capita carbon emissions in the three economic regions of China between 1997 and 2009 was economic development, and the energy efficiency was much greater than the energy structure after considering their effect on restraining increased per-capita carbon emissions. (3) Based on the decomposition, the factors that affected per-capita carbon emissions in the panel co-integration test showed that Central China had the best energy structure elasticity in its regional per-capita carbon emissions. Thus, Central China was ranked first for energy efficiency elasticity, while Western China was ranked first for economic development elasticity. PMID:24353753

  12. Interfície gràfica per WPKG - distribució de programari

    OpenAIRE

    Garcia Morant, Josep

    2012-01-01

    Interfície gràfica per a la gestió del programari de lliure accés per a la distribució de programari WPKG (wpkg.org). Arquitectura MVC en un entorn J2EE6 utilitzant JSF2, JPA2 i EJB 3.1. Interfaz gráfica para la gestión del software de libre acceso para la distribución de software WPKG (wpkg.org). Arquitectura MVC en un entorno J2EE6 utilizando JSF2, JPA2 y EJB 3.1.

  13. Pulsation of IU Per from the Ground-based and ‘Integral’ Photometry

    Directory of Open Access Journals (Sweden)

    Kundra E.

    2013-06-01

    Full Text Available IU Per is an eclipsing semi-detached binary with a pulsating component. Using our own ground-based, as well as INTEGRAL satellite photometric observations in the B and V passbands, we derived geometrical and physical parameters of this system. We detected the short-term variations of IU Per in the residuals of brightness after the subtraction of synthetic light curves. Analysis of these residuals enabled us to characterize and localize the source of short-term variations as the pulsations of the primary component typical to δ Scuti-type stars.

  14. Demonstration of coupling correction below the per-mil limit in the LHC

    CERN Document Server

    Maclean, Ewen Hamish; Fartoukh, Stephane; Persson, Tobias Hakan Bjorn; Skowronski, Piotr Krzysztof; Tomas Garcia, Rogelio; Wierichs, David Alexander; CERN. Geneva. ATS Department

    2016-01-01

    Linear coupling between betatron motion in the transverse planes is one of the key optics parameters for any accelerator. It can substantially affect the nonlinear dynamics, influencing both lifetime and the damping of instabilities, as well as affecting the ability to measure and control the linear optics. A review of published material revealed no account of coupling having been corrected significantly below the per-mil level in any hadron accelerator. This note reports the achievement of a sub-per-mil coupling correction during an LHC Machine Development study.

  15. High prevalence of the PER-1 gene among carbapenem-resistant Acinetobacter baumannii in Riyadh, Saudi Arabia.

    Science.gov (United States)

    Aly, M M; Abu Alsoud, N M; Elrobh, M S; Al Johani, S M; Balkhy, H H

    2016-11-01

    The prevalence of carbapenem-resistant Acinetobacter baumannii in Saudi Arabia and their resistance genetic mechanisms are yet to be identified. We studied the prevalence and genetic diversity of extended-spectrum beta-lactamase genes, particularly the PER-1 gene, among carbapenem-resistant A. baumannii strains from patients at a tertiary care hospital in Riyadh, Saudi Arabia between 2006 and 2014. Fresh subcultured samples were tested for antimicrobial susceptibility minimum inhibitory concentration (MIC). Total genomic DNA was extracted from each isolate and further used for polymerase chain reaction (PCR) genotyping, sequence-based typing (SBT) of PER-1 and OXA-51-like gene, and multilocus sequence typing (MLST) of positive isolates. Randomly selected clinical isolates (n = 100) were subjected to MLST. A total of 503 isolates were characterized as multidrug-resistant (MDR) using the MIC. Isolates were further PCR tested for bla -TEM and bla -PER-1 resistance genes (n = 503). The genotyping results showed that 68/503 (14 %) isolates were positive to bla TEM. The genotyping results of PER-1-like genes showed that 384/503 (76.3 %) were positive among MDR Acinetobacter isolates. Based on SBT, the majority of these isolates were clustered into three main groups including isolates harboring PER-1: AB11 (bla -PER-1 ), isolate AB16 (bla -PER-1 ), and, finally, the plasmid pAB154 (bla -PER-7 ). Remarkably, many isolates were concealing the PER-1 gene and harboring the TEM resistance genes as well. MLST results for selected isolates (n = 100) identified four main sequence types (STs: 2, 19, 20, and 25) and four novel isolates (ST 486-489). We report 76.3 % prevalence of the PER-1 resistance gene among Acinetobacter clinical isolates from Riyadh, Saudi Arabia. Further work is needed to explore the clinical risks and patient outcome with such resistance related to healthcare-associated infections and investigate the genetic and molecular mechanisms that confer the MDR

  16. Drosophila TIM binds importin α1, and acts as an adapter to transport PER to the nucleus.

    Science.gov (United States)

    Jang, A Reum; Moravcevic, Katarina; Saez, Lino; Young, Michael W; Sehgal, Amita

    2015-02-01

    Regulated nuclear entry of clock proteins is a conserved feature of eukaryotic circadian clocks and serves to separate the phase of mRNA activation from mRNA repression in the molecular feedback loop. In Drosophila, nuclear entry of the clock proteins, PERIOD (PER) and TIMELESS (TIM), is tightly controlled, and impairments of this process produce profound behavioral phenotypes. We report here that nuclear entry of PER-TIM in clock cells, and consequently behavioral rhythms, require a specific member of a classic nuclear import pathway, Importin α1 (IMPα1). In addition to IMPα1, rhythmic behavior and nuclear expression of PER-TIM require a specific nuclear pore protein, Nup153, and Ran-GTPase. IMPα1 can also drive rapid and efficient nuclear expression of TIM and PER in cultured cells, although the effect on PER is mediated by TIM. Mapping of interaction domains between IMPα1 and TIM/PER suggests that TIM is the primary cargo for the importin machinery. This is supported by attenuated interaction of IMPα1 with TIM carrying a mutation previously shown to prevent nuclear entry of TIM and PER. TIM is detected at the nuclear envelope, and computational modeling suggests that it contains HEAT-ARM repeats typically found in karyopherins, consistent with its role as a co-transporter for PER. These findings suggest that although PER is the major timekeeper of the clock, TIM is the primary target of nuclear import mechanisms. Thus, the circadian clock uses specific components of the importin pathway with a novel twist in that TIM serves a karyopherin-like role for PER.

  17. Contribution Of Human Development Index On Per Capita Income Growth And Poverty Alleviation In Indonesia

    OpenAIRE

    Sudarlan

    2015-01-01

    Abstract The development of a country usually determined by the human development index HDI. Per capita income education and health are the three most important components of human development index. The purpose of this research is to understand the relationship among human development index to income per capita growth and poverty alleviation in Indonesia with cross-section data from 30 provinces period 2002 2011 year. The result of this research were a income per capita growth was not sign...

  18. Direct and specific effect of sevoflurane anesthesia on rat Per2 expression in the suprachiasmatic nucleus.

    Directory of Open Access Journals (Sweden)

    Megumi Anzai

    Full Text Available BACKGROUND: Our previous studies revealed that application of the inhalation anesthetic, sevoflurane, reversibly repressed the expression of Per2 in the mouse suprachiasmatic nucleus (SCN. We aimed to examine whether sevoflurane directly affects the SCN. METHODS: We performed in vivo and in vitro experiments to investigate rat Per2 expression under sevoflurane-treatment. The in vivo effects of sevoflurane on rPer2 expression were examined by quantitative in situ hybridization with a radioactively-labeled cRNA probe. Additionally, we examined the effect of sevoflurane anesthesia on rest/activity rhythms in the rat. In the in vitro experiments, we applied sevoflurane to SCN explant cultures from Per2-dLuc transgenic rats, and monitored luciferase bioluminescence, representing Per2 promoter activity. Bioluminescence from two peripheral organs, the kidney cortex and the anterior pituitary gland, were also analyzed. RESULTS: Application of sevoflurane in rats significantly suppressed Per2 expression in the SCN compared with untreated animals. We observed no sevoflurane-induced phase-shift in the rest/activity rhythms. In the in vitro experiments, the intermittent application of sevoflurane repressed the increase of Per2-dLuc luminescence and led to a phase delay in the Per2-dLuc luminescence rhythm. Sevoflurane treatment did not suppress bioluminescence in the kidney cortex or the anterior pituitary gland. CONCLUSION: The suppression of Per2-dLuc luminescence by sevoflurane in in vitro SCN cultures isolated from peripheral inputs and other nuclei suggest a direct action of sevoflurane on the SCN itself. That sevoflurane has no such effect on peripheral organs suggests that this action might be mediated through a neuron-specific cellular mechanism or a regulation of the signal transduction between neurons.

  19. Segment-Tube: Spatio-Temporal Action Localization in Untrimmed Videos with Per-Frame Segmentation

    OpenAIRE

    Le Wang; Xuhuan Duan; Qilin Zhang; Zhenxing Niu; Gang Hua; Nanning Zheng

    2018-01-01

    Inspired by the recent spatio-temporal action localization efforts with tubelets (sequences of bounding boxes), we present a new spatio-temporal action localization detector Segment-tube, which consists of sequences of per-frame segmentation masks. The proposed Segment-tube detector can temporally pinpoint the starting/ending frame of each action category in the presence of preceding/subsequent interference actions in untrimmed videos. Simultaneously, the Segment-tube detector produces per-fr...

  20. 76 FR 55273 - Federal Travel Regulation; Per Diem, Miscellaneous Amendments

    Science.gov (United States)

    2011-09-07

    ... Travel Regulation; Per Diem, Miscellaneous Amendments AGENCY: Office of Governmentwide Policy, General...) reimbursement on travel days; extending agencies the authority to issue blanket actual expense approval for TDY...; 0 b. By removing ``agency'' and adding ``agency's Travel Manager'' in its place whenever it appears...

  1. Justice organisationnelle perçue des pratiques de gestion des ...

    African Journals Online (AJOL)

    Mots clés : Pratiques de GRH, Justice organisationnelle perçue, Engagement organisationnel. ABSTRACT. This study aims at measuring the mediator effect of the organizational justice perceived in the relation between the practices of human stock management and the organizational commitment of the employees.

  2. Tests of equal effect per fraction in microcolony assays of survival after fractionated irradiations

    International Nuclear Information System (INIS)

    Taylor, J.M.G.

    1985-01-01

    H.D Thames, Jr. and H.R. Withers propose a test of an equal effect per fraction in microcolony assays after fractionated radiation, in which the total effect is measured by counting microcolonies derived from surviving cells in a tissue. The factors considered to influence the cytocidal effect per fraction are incomplete repair, repopulation, and synchrony. The statistics used in the method are criticized and conditions are given under which the test should not be used. An alternative method of testing for an equal effect per fraction is proposed. The pros and cons of each test are discussed and compared using some mouse jejunal crypt cell survival data

  3. enfermagem, no período de 1980 a 2005

    Directory of Open Access Journals (Sweden)

    Denize Cristina de Oliveira

    2006-01-01

    Full Text Available Se trata de una investigación cuantitativa, tipo descriptivo, que tuvo como objetivos identificar y analizar la literatura científica publicada en los periódicos brasileños de enfermería sobre VIH/SIDA, en el período de 1980 al 2005. Los bancos de datos seleccionados fueron: BVS-Enfermería, con descriptores “HIV or AIDS”; LILACS, SCIELO, Portal CAPES y BIREME, con los descriptores “HIV or AIDS and enfermagem”. Los idiomas fueron portugués, inglés y español. Los resultados demostraron que la mayoría de los estudios sobre VIH/SIDA fueron publicados en el período de 2000 al 2005, destacándose las investigaciones de abordaje cualitativo descriptivo. Los pacientes con VIH o SIDA seropositivos fueron los sujetos más recientemente. El tema predominante fue cuidar de pacientes con VIH/SIDA. Se concluye que existe el interés por el VIH/SIDA y que este interés se asocia al conjunto de las prácticas profesionales en el campo de estudio.

  4. Lifetime and per year productivity of sows in four pig farms in the tropics of Mexico.

    Science.gov (United States)

    Ek-Mex, Jesús Enrique; Segura-Correa, José Candelario; Alzina-López, Alejandro; Batista-Garcia, Laura

    2015-03-01

    The objectives of this study were to estimate the lifetime and per year productivity of sows and to determine the effect of some factor on those traits in four pig farms in the tropics of Mexico. Data from 7526 sows for lifetime number of piglets born alive per sow (LBA), lifetime kilograms of piglets at farrowing (LKF), number of piglets born alive per year (NPF/Y), and kilograms of piglets at farrowing per year (KPF/Y); and data from 7230 sows for lifetime number of piglets weaned (LPW), lifetime kilograms of piglets weaned (LKW), number of piglets weaned per year (NPW/Y), and kilograms of piglets weaned per year (KPW/Y) per sow were used. The statistical model for all traits included the fixed effects of farm, year of first farrowing, season of first farrowing, litter size at first farrowing, age at first farrowing, removal reason, simple interactions, and the error term. The means for LBA, LKF, NPF/Y, and KPF/Y were 45.1 piglets, 67.1 kg, 22.7 piglets, and 33.7 kg, respectively. The means for LPW, LKW, NPW/Y, and KPW/Y were 43.2 piglets, 251.9 kg, 21.5 piglets, and 125.1 kg, respectively. All factors were significant for all traits, except for age at first farrowing on LPW and LKW. Sows with large litter sizes and those that farrowed the first time, at an early age, had the highest lifetime and per year productivity. Therefore, more care and better management should be provided to those types of sows to improve the farms profit.

  5. Responsabilidad social empresarial en el Perú

    Directory of Open Access Journals (Sweden)

    Manuel Porro Rivadeneira

    2008-06-01

    Full Text Available Como parte del crecimiento y el desarrollo de los agentes económicos se ha creído conveniente analizar una institución de reciente data que afecta de modo especial a los grupos de interés (stakeholders unidos a la empresa, es por ello que la presente investigación pretende analizar de modo amplio y general los aspectos más relevantes de la Responsabilidad Social Empresarial así como aquellos de difícil tratamiento y de modo específico resolveremos la pregunta ¿cómo ha avanzado en materia de instrumentalización y normatividad la Responsabilidad Social Empresarial en el Perú?

  6. Un approccio multidisciplinare per l’archeologia digitale

    Directory of Open Access Journals (Sweden)

    Rodolfo Maria Strollo

    2017-12-01

    Full Text Available Obiettivo del contributo è quello di indagare le potenzialità offerte da una metodologia multidisciplinare volta alla creazione di un database digitale facilmente interrogabile, sempre disponibile e scientificamente valido da impiegare per le diverse finalità legate al patrimonio culturale immobile (ricerca scientifica, interventi di manutenzione e restauro, valorizzazione culturale, promozione turistica. La banca dati è composta da modelli infografici elaborati con riferimento a rilievi tridimensionali affidabili dal punto di vista metrico e cromatico e rappresentativi di una realtà virtuale ‘aumentata’ delle informazioni storiche, iconografico-documentali e archivistiche riferite al bene. Caso studio su cui è stato sperimentato tale approccio metodologico è l’area archeologica di Tuscolo, sui Colli Albani a sud di Roma.

  7. Responsabilidad social empresarial en el Perú

    Directory of Open Access Journals (Sweden)

    Manuel Porro Rivadeneira

    2008-07-01

    Full Text Available Como parte del crecimiento y el desarrollo de los agentes económicos se ha creído conveniente analizar una institución de reciente data que afecta de modo especial a los grupos de interés (stakeholders unidos a la empresa, es por ello que la presente investigación pretende analizar de modo amplio y general los aspectos más relevantes de la Responsabilidad Social Empresarial así como aquellos de difícil tratamiento y de modo específico resolveremos la pregunta ¿cómo ha avanzado en materia de instrumentalización y normatividad la Responsabilidad Social Empresarial en el Perú?

  8. Crassulaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Crassulaceae es reconocida en el Perú por presentar cinco géneros y 29 especies (Brako & Zarucchi, 1993, mayormente arbustos y hierbas. En este trabajo reconocemos 13 especies y dos variedades como endemismos peruanos en tres géneros. Echeveria es el género con el mayor número de especies endémicas. Los taxones endémicos ocupan principalmente las regiones Mesoandina y Puna Húmeda y Seca, entre los 1700 y 4500 m de altitud. Se aplicaron las categorías y criterios de la UICN a nueve taxones. Dos Crassulaceae endémicas están representados dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  9. Cyatheaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available Esta es una de las familias que incluye mayormente helechos arborescentes. En el Perú, esta familia está representada por cuatro géneros y más de 60 especies (Tryon & Stolze 1989a, Smith et al., 2005. Siete especies en dos géneros son consideradas endemismos peruanos, estando escasamente representadas en los herbarios. La mayoría de estos endemismos se encuentra en los bosques de las regiones del Bosque Húmedo Montano y Premontano en el centro y sur del país, entre los 850 y 3300 m de altitud, generalmente asociados a localidades escasamente herborizadas. Cuatro de esas especies se conocen de áreas protegidas.

  10. La gestión de responsabilidad social empresarial de las empresas mineras en el Perú y su incidencia en el desarrollo sostenible de las comunidades de su entorno - período 2004 - 2014

    OpenAIRE

    Espinoza Guadalupe, Ladislao

    2015-01-01

    Determina la incidencia de la gestión de responsabilidad social empresarial de las empresas mineras en el Perú, en el desarrollo sostenible de las comunidades ubicada en su entorno - período 2004 - 2014. A partir de ello, y teniendo en cuenta la realidad problemática, se han derivado los siguientes objetivos: Determinar la incidencia del desempeño social, económico e incidencia ambiental de las empresas mineras en el Perú, así como proponer un conjunto de ratios de sostenibilidad basados en i...

  11. EnviroAtlas - Durham, NC - Domestic Water Use per Day by U.S. Census Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — As included in this EnviroAtlas dataset, the community domestic water use was calculated using locally available water use data per capita in gallons of water per...

  12. Mechanisms of direct inhibition of the respiratory sulfate-reduction pathway by (per)chlorate and nitrate.

    Science.gov (United States)

    Carlson, Hans K; Kuehl, Jennifer V; Hazra, Amrita B; Justice, Nicholas B; Stoeva, Magdalena K; Sczesnak, Andrew; Mullan, Mark R; Iavarone, Anthony T; Engelbrektson, Anna; Price, Morgan N; Deutschbauer, Adam M; Arkin, Adam P; Coates, John D

    2015-06-01

    We investigated perchlorate (ClO(4)(-)) and chlorate (ClO(3)(-)) (collectively (per)chlorate) in comparison with nitrate as potential inhibitors of sulfide (H(2)S) production by mesophilic sulfate-reducing microorganisms (SRMs). We demonstrate the specificity and potency of (per)chlorate as direct SRM inhibitors in both pure cultures and undefined sulfidogenic communities. We demonstrate that (per)chlorate and nitrate are antagonistic inhibitors and resistance is cross-inducible implying that these compounds share at least one common mechanism of resistance. Using tagged-transposon pools we identified genes responsible for sensitivity and resistance in Desulfovibrio alaskensis G20. We found that mutants in Dde_2702 (Rex), a repressor of the central sulfate-reduction pathway were resistant to both (per)chlorate and nitrate. In general, Rex derepresses its regulon in response to increasing intracellular NADH:NAD(+) ratios. In cells in which respiratory sulfate reduction is inhibited, NADH:NAD(+) ratios should increase leading to derepression of the sulfate-reduction pathway. In support of this, in (per)chlorate or nitrate-stressed wild-type G20 we observed higher NADH:NAD(+) ratios, increased transcripts and increased peptide counts for genes in the core Rex regulon. We conclude that one mode of (per)chlorate and nitrate toxicity is as direct inhibitors of the central sulfate-reduction pathway. Our results demonstrate that (per)chlorate are more potent inhibitors than nitrate in both pure cultures and communities, implying that they represent an attractive alternative for controlling sulfidogenesis in industrial ecosystems. Of these, perchlorate offers better application logistics because of its inhibitory potency, solubility, relative chemical stability, low affinity for mineral cations and high mobility in environmental systems.

  13. EnviroAtlas - Portland, OR - Domestic Water Use per Day by U.S. Census Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — As included in the EnviroAtlas, the community level domestic water use is calculated using locally available water use data per capita in gallons of water per day...

  14. EnviroAtlas - Paterson, NJ - Domestic Water Use per Day by U.S. Census Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — As included in the EnviroAtlas, the community level domestic water use is calculated using locally available water use data per capita in gallons of water per day...

  15. EnviroAtlas - Portland, ME - Domestic Water Use per Day by U.S. Census Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — As included in this EnviroAtlas dataset, the community domestic water use was calculated using local domestic water use per capita in gallons of water per day (GPD),...

  16. Optimal Multiuser Zero Forcing with Per-Antenna Power Constraints for Network MIMO Coordination

    Directory of Open Access Journals (Sweden)

    Kaviani Saeed

    2011-01-01

    Full Text Available We consider a multicell multiple-input multiple-output (MIMO coordinated downlink transmission, also known as network MIMO, under per-antenna power constraints. We investigate a simple multiuser zero-forcing (ZF linear precoding technique known as block diagonalization (BD for network MIMO. The optimal form of BD with per-antenna power constraints is proposed. It involves a novel approach of optimizing the precoding matrices over the entire null space of other users' transmissions. An iterative gradient descent method is derived by solving the dual of the throughput maximization problem, which finds the optimal precoding matrices globally and efficiently. The comprehensive simulations illustrate several network MIMO coordination advantages when the optimal BD scheme is used. Its achievable throughput is compared with the capacity region obtained through the recently established duality concept under per-antenna power constraints.

  17. Discorso globale e contesti locali. Quale futuro per il programma di riforma agraria in Ruanda?

    Directory of Open Access Journals (Sweden)

    Johan Pottier

    2013-07-01

    Full Text Available La maggior parte degli sforzi per trasformare l’economia sub-sahariana negli anni Ottanta e Novanta faceva seguito ai cosiddetti “accordi di Washington”; questi sforzi avevano l’obiettivo di ridimensionare il ruolo dello Stato e liberalizzare i prezzi agricoli. La strategia prescritta funzionò per alcuni, ma non per la maggioranza dei produttori agricoli; all’inizio del XXI secolo è necessario, ancora una volta, un “momento di ripensamento”. I responsabili delle politiche agricole suggeriscono ora che,per indurre un cambiamento efficace, il nuovo modo di pensare deve fare i conti con modelli inappropriati di coltivazione, cogliere le dimensioni sociali e politiche dei cambiamenti indotti dalle moderne tecniche di coltivazione e venire a patti con i locali modi di comprensione dei contesti complessi (Scoones, Devereux, Haddad 2005, p. 3.

  18. Comunità virtuali per l'apprendimento e nuove tecnologie

    Directory of Open Access Journals (Sweden)

    Stefania Manca

    2002-01-01

    Full Text Available Le comunita' virtuali per l'apprendimento rivestono oggi particolare interesse in ambito formativo in quanto sembrano sancire definitivamente un cambiamento di paradigma teorico e metodologico. L'idea costruttivista ha, infatti, progressivamente sostituito il modello tradizionale del trasferimento di conoscenza, secondo cui apprendere significa essere in grado di esibire conoscenze e capacita' oggettivamente misurabili, decontestualizzate e aventi valore di verita' oggettive, universalmente confrontabili.

  19. PER3 VNTR polymorphism in Multiple Sclerosis: A new insight to impact of sleep disturbances in MS.

    Science.gov (United States)

    Golalipour, Masoud; Maleki, Zahra; Farazmandfar, Touraj; Shahbazi, Majid

    2017-10-01

    Multiple Sclerosis (MS) is a degenerative disease of central nervous system caused by an immune response against the myelin. About half of MS patients suffers from sleep disturbances. The circadian clock genes such as PER3 controls circadian rhythm and sleep. Due to the role of PER3 in sleep disturbances and regulation of immune response, it is possible that PER3 dysregulation increase risk of MS disease. Study groups included 160 MS patients and 160 healthy volunteers. PER3 VNTR polymorphism was evaluated by PCR method. The genotypic and allelic distribution analyzed by chi square test. There was a significant association between genotype PER3 4/4 , and 4-repeat allele with MS disease (p = 0.014 and p MS group, and MS onset showed that there was a significant correlation between PER3 4/4 genotype with female gender and early onset of MS disease (p = 0.033 and p = 0.028 respectively). Our data suggest that, PER3 4/4 genotype may accelerate the course of disease in MS susceptible individuals. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Dorsomedial prefontal cortex supports spontaneous thinking per se.

    Science.gov (United States)

    Raij, T T; Riekki, T J J

    2017-06-01

    Spontaneous thinking, an action to produce, consider, integrate, and reason through mental representations, is central to our daily experience and has been suggested to serve crucial adaptive purposes. Such thinking occurs among other experiences during mind wandering that is associated with activation of the default mode network among other brain circuitries. Whether and how such brain activation is linked to the experience of spontaneous thinking per se remains poorly known. We studied 51 healthy subjects using a comprehensive experience-sampling paradigm during 3T functional magnetic resonance imaging. In comparison with fixation, the experiences of spontaneous thinking and spontaneous perception were related to activation of wide-spread brain circuitries, including the cortical midline structures, the anterior cingulate cortex and the visual cortex. In direct comparison of the spontaneous thinking versus spontaneous perception, activation was observed in the anterior dorsomedial prefrontal cortex. Modality congruence of spontaneous-experience-related brain activation was suggested by several findings, including association of the lingual gyrus with visual in comparison with non-verbal-non-visual thinking. In the context of current literature, these findings suggest that the cortical midline structures are involved in the integrative core substrate of spontaneous thinking that is coupled with other brain systems depending on the characteristics of thinking. Furthermore, involvement of the anterior dorsomedial prefrontal cortex suggests the control of high-order abstract functions to characterize spontaneous thinking per se. Hum Brain Mapp 38:3277-3288, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  1. High laboratory cost predicted per tuberculosis case diagnosed with increased case finding without a triage strategy.

    Science.gov (United States)

    Dunbar, R; Naidoo, P; Beyers, N; Langley, I

    2017-09-01

    Cape Town, South Africa. To model the effects of increased case finding and triage strategies on laboratory costs per tuberculosis (TB) case diagnosed. We used a validated operational model and published laboratory cost data. We modelled the effect of varying the proportion with TB among presumptive cases and Xpert cartridge price reductions on cost per TB case and per additional TB case diagnosed in the Xpert-based vs. smear/culture-based algorithms. In our current scenario (18.3% with TB among presumptive cases), the proportion of cases diagnosed increased by 8.7% (16.7% vs. 15.0%), and the cost per case diagnosed increased by 142% (US$121 vs. US$50). The cost per additional case diagnosed was US$986. This would increase to US$1619 if the proportion with TB among presumptive cases was 10.6%. At 25.9-30.8% of TB prevalence among presumptive cases and a 50% reduction in Xpert cartridge price, the cost per TB case diagnosed would range from US$50 to US$59 (comparable to the US$48.77 found in routine practice with smear/culture). The operational model illustrates the effect of increased case finding on laboratory costs per TB case diagnosed. Unless triage strategies are identified, the approach will not be sustainable, even if Xpert cartridge prices are reduced.

  2. Protease activity of Per a 10 potentiates Th2 polarization by increasing IL-23 and OX40L.

    Science.gov (United States)

    Agrawal, Komal; Kale, Sagar L; Arora, Naveen

    2015-12-01

    Proteases are implicated in exacerbation of allergic diseases. In this study, the role of proteolytic activity of Per a 10 was evaluated on Th2 polarization. Intranasal administration of Per a 10 in mice led to allergic airway inflammation as seen by higher IgE levels, cellular infiltration, IL-17A, and Th2 cytokines, whereas, inactive (Δ)Per a 10 showed attenuated response. There was an increased OX40L expression on lung and lymph node dendritic cells in Per a 10 immunized group and on Per a 10 stimulated BMDCs. Reduction in CD40 expression without any change at transcript level in lungs of Per a 10 immunized mice suggested CD40 cleavage. BMDCs pulsed with Per a 10 showed reduced CD40 expression with lower IL-12p70 secretion as compared to heat inactivated Per a 10. IL-23, TNF-α, and IL-6 levels were significantly higher in Per a 10 stimulated BMDCs supernatant. In DC-T cell coculture studies, Per a 10 pulsed BMDCs showed higher levels of IL-4 and IL-13 that were reduced on blocking of either IL-23 or OX40L. In conclusion, the data suggests a critical role of protease activity of Per a 10 in promoting Th2 polarization by increasing IL-23 secretion and OX40L expression on dendritic cells. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Schadenfreude: il piacere per le disgrazie altrui (Virginio Sala, Trans.)

    NARCIS (Netherlands)

    van Dijk, W.; Ouwerkerk, J.W.

    2016-01-01

    Quando qualcuno è colpito da una sventura, un incidente o una disgrazia, a volte proviamo Schadenfreude: un’emozione che si definisce solitamente come “provare piacere per la sventura altrui”. Quella della Schadenfreude è un’esperienza comune: è un’emozione che sembra intrinseca all’essere sociale.

  4. Subway e skyway: infrastrutture sostenibili per la mobilità pedonale?

    Directory of Open Access Journals (Sweden)

    Enrica Papa

    2008-12-01

    Full Text Available L’articolo propone un approfondimento su una particolare tipologia di sistemi per la mobilità pedonale: le reti pedonali dedicate. Questa tipologia di infrastrutture per la mobilità pedonale è caratterizzata da assi pedonali sotterranei (subway e sopraelevati (skyway che si strutturano come complesse strutture percorribili solo a piedi. Gli esempi emblematici sono la più ampia rete pedonale sotterranea del mondo di Montreal, che raggiunge un estensione di 32km ed è conosciuta come la ville intérieure e la rete sopraelevata di Calgary, che supera i 16km di passaggi pedonali di collegamento tra diversi edifici commerciali e terziari. Partendo da un’analisi comparativa di casi di studio, l’articolo descrive gli elementi caratteristici delle reti pedonali “non convenzionali”, mettendo in evidenza i punti di forza e di debolezza di questi esempi in cui il flusso pedonale è totalmente separato dagli spazi dedicati al traffico veicolare.

  5. Persönlichkeit der Fussballer AMP Futbol = Personality footballers AMP Futbol

    Directory of Open Access Journals (Sweden)

    Paweł Kalinowski

    2016-08-01

    Full Text Available Kalinowski, Paweł, Lischka Ołpińska, Marta . Persönlichkeit der Fussballer AMP Futbol = Personality footballers AMP Futbol. Journal of Education, Health and Sport. 2016;6(8:227-235. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.60260 http://ojs.ukw.edu.pl/index.php/johs/article/view/3751       The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015. 755 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Author (s 2016; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 15.07.2016. Revised 25.07.2016. Accepted: 12.08.2016.   QUALITY IN SPORT 3 (2 2016, s. 65-72, e-ISSN 2450-3118 Praca wpłynęła do redakcji 13 III 2016, praca została przyjęta do druku 23 VI 2016 DOI: http://dx.doi.org/10.5281/zenodo.57217 PBN: https://pbn.nauka.gov.pl/sedno-webapp/works/735282     Paweł Kalinowski[1], Marta Lischka Ołpińska Doktoranden AWF Pozna

  6. Tratamiento tributario del factoring en el Perú

    OpenAIRE

    Rocío Liu Arévalo; Eduardo Sotelo Castañeda

    2015-01-01

    Una de las alternativas de financiamiento que tienen las empresas a su alcance es la que se presenta a través del contrato de factoring. En virtud de dicho contrato una de las partes - factor- adquiere todos o una parte de los créditos que la otra parte - factorado - tiene frente a terceros, adelantándole a cambio el importe de los mismos. En el presente artículo, los autores describen y analizan el régimen tributario aplicable al contrato de factoring en el Perú, p...

  7. Registre d'entrades i eixides per a l'administració pública

    OpenAIRE

    Oliver Company, Alfredo

    2005-01-01

    Aquesta memòria representa la definició del meu projecte final de carrera amb una aplicació destinada al registre d'entrades i eixides de l'Administració pública. He emprat eines de plataformes lliures i obertes per al desenvolupament del projecte, amb tecnologia J2EE. A més, hi ha l'objectiu de fer servir i provar arquitectures d'última generació com Enterprise JavaBeans Preview_2 (EJB) 3.0 (5/11/04) per a la lògica de negoci, Hibernate 3.0 alpha (actualment hi ha la beta 1.0 publicada el 20...

  8. Definition and evolution of quantum cellular automata with two qubits per cell

    International Nuclear Information System (INIS)

    Karafyllidis, Ioannis G.

    2004-01-01

    Studies of quantum computer implementations suggest cellular quantum computer architectures. These architectures can simulate the evolution of quantum cellular automata, which can possibly simulate both quantum and classical physical systems and processes. It is however known that except for the trivial case, unitary evolution of one-dimensional homogeneous quantum cellular automata with one qubit per cell is not possible. Quantum cellular automata that comprise two qubits per cell are defined and their evolution is studied using a quantum computer simulator. The evolution is unitary and its linearity manifests itself as a periodic structure in the probability distribution patterns

  9. Per tree estimates with n-tree distance sampling: an application to increment core data

    Science.gov (United States)

    Thomas B. Lynch; Robert F. Wittwer

    2002-01-01

    Per tree estimates using the n trees nearest a point can be obtained by using a ratio of per unit area estimates from n-tree distance sampling. This ratio was used to estimate average age by d.b.h. classes for cottonwood trees (Populus deltoides Bartr. ex Marsh.) on the Cimarron National Grassland. Increment...

  10. Specific B-cell Epitope of Per a 1: A Major Allergen of American Cockroach (Periplaneta americana) and Anatomical Localization.

    Science.gov (United States)

    Sookrung, Nitat; Khetsuphan, Thanyathon; Chaisri, Urai; Indrawattana, Nitaya; Reamtong, Onrapak; Chaicumpa, Wanpen; Tungtrongchitr, Anchalee

    2014-07-01

    Cockroach (CR) is a common source of indoor allergens, and Per a 1 is a major American CR (Periplaneta americana) allergen; however, several attributes of this protein remain unknown. This study identifies a novel specific B cell epitope and anatomical locations of Per a 1.0105. Recombinant Per a 1.0105 (rPer a 1.0105) was used as BALB/c mouse immunogen for the production of monoclonal antibodies (MAb). The MAb specific B cell epitope was identified by determining phage mimotopic peptides and pair-wise alignment of the peptides with the rPer a 1.0105 amino acid sequence. Locations of the Per a 1.0105 in P. americana were investigated by immunohistochemical staining. The rPer a 1.0105 (~13 kDa) had 100%, 98% and ≥90% identity to Per a 1.0105, Per a 1.0101, and Cr-PII, respectively. The B-cell epitope of the Per a 1.0105 specific-MAb was located at residues(99) QDLLLQLRDKGV(110) contained in all 5 Per a 1.01 isoforms and Per a 1.02. The epitope was analogous to the Bla g 1.02 epitope; however, this B-cell epitope was not an IgE inducer. Per a 1.0105 was found in the midgut and intestinal content of American CR but not in the other organs. The amount of the Per a 1 was ~544 ℃g per gram of feces. The novel Per a 1 B-cell epitope described in this study is a useful target for allergen quantification in samples; however, the specific MAb can be used as an allergen detection reagent. The MAb based-affinity resin can be made for allergen purification, and the so-purified protein can serve as a standard and diagnostic allergen as well as a therapeutic vaccine component. The finding that the Per a 1 is contained in the midgut and feces is useful to increase yield and purity when preparing this allergen.

  11. Per operative discovery of Placenta Praevia Percreta: A case report ...

    African Journals Online (AJOL)

    Placenta percreta is a rare pathological entity with challenging diagnostic and therapeutic requirements especially for resource limited settings. We present here the case of a 40 year old woman with a per operative diagnosis of placenta accreta during a caesarian section indicated for placenta praevia. We highlight the ...

  12. Työohjeistus Perälän Turve Oy

    OpenAIRE

    Haukka, Arto

    2014-01-01

    Perälän Turve Oy:n uusille työntekijöille laadittu työohjeistus ja siitä raportointi. Työhön kuuluu kaksi osaa, word-raportti sekä powerpoint-työohjeistuskansio. Powerpoint-tiedosto upotettuna tiedostona alkuperäisessä word-tiedostossa.

  13. The value of the per oral pneumocolon in the study of the distal ileal loops

    International Nuclear Information System (INIS)

    Minordi, L.M.; Vecchioli, A.; Dinardo, G.; Bonomo, L.

    2006-01-01

    Aim: To verify the diagnostic accuracy of per oral pneumocolon in the identification of both normal and pathological patterns in patients with suspected or proven small bowel disease. Materials and methods: Per oral pneumocolon was performed after small bowel follow-through examinations in a series of 42 selected patients. The terminal ileum visibility, the loop location and possible pathological patterns were evaluated separately before and after insufflation. In post-insufflation images the presence/absence of reflux and grade of reflux were evaluated. Results: The diagnostic quality of per oral pneumocolon as compared with per oral small bowel examination was superior in 23 of the 42 patients (54.8%; group 1), similar in nine of the 42 (21.4%; group 2), and inferior in 10 of the 42 (23.8%; group 3). Transvalvular reflux was present in 22 of 23 (95.6%) patients from group 1 and only in one of 10 patients (10%) from group 3 (p < 0.001: statistically significant difference). Among the 24 of 42 (57.1%) patients with suspected or proven Crohn's disease, per oral pneumocolon increased the confidence with which the ileum was considered normal in 12 patients and it allowed a better evaluation of the disease extent and the differentiation between prolonged spasms and stenosis in five patients. Conclusion: In conclusion per oral pneumocolon should be performed after a small bowel follow-through examination in selected patients

  14. Factors associated with geographic variation in cost per episode of care for three medical conditions

    Science.gov (United States)

    2014-01-01

    Objective To identify associations between market factors, especially relative reimbursement rates, and the probability of surgery and cost per episode for three medical conditions (cataract, benign prostatic neoplasm, and knee degeneration) with multiple treatment options. Methods We use 2004–2006 Medicare claims data for elderly beneficiaries from sixty nationally representative communities to estimate multivariate models for the probability of surgery and cost per episode of care as a function local market factors, including Medicare physician reimbursement for surgical versus non-surgical treatment and the availability of primary care and specialty physicians. We used Symmetry’s Episode Treatment Groups (ETG) software to group claims into episodes for the three conditions (n = 540,874 episodes). Results Higher Medicare reimbursement for surgical episodes and greater availability of the relevant specialists are significantly associated with more surgery and higher cost per episode for all three conditions, while greater availability of primary care physicians is significantly associated with less frequent surgery and lower cost per episode. Conclusion Relative Medicare reimbursement rates for surgical vs. non-surgical treatments and the availability of both primary care physicians and relevant specialists are associated with the likelihood of surgery and cost per episode. PMID:24949281

  15. DNA adenine methylation is required to replicate both Vibrio cholerae chromosomes once per cell cycle.

    Science.gov (United States)

    Demarre, Gaëlle; Chattoraj, Dhruba K

    2010-05-06

    DNA adenine methylation is widely used to control many DNA transactions, including replication. In Escherichia coli, methylation serves to silence newly synthesized (hemimethylated) sister origins. SeqA, a protein that binds to hemimethylated DNA, mediates the silencing, and this is necessary to restrict replication to once per cell cycle. The methylation, however, is not essential for replication initiation per se but appeared so when the origins (oriI and oriII) of the two Vibrio cholerae chromosomes were used to drive plasmid replication in E. coli. Here we show that, as in the case of E. coli, methylation is not essential for oriI when it drives chromosomal replication and is needed for once-per-cell-cycle replication in a SeqA-dependent fashion. We found that oriII also needs SeqA for once-per-cell-cycle replication and, additionally, full methylation for efficient initiator binding. The requirement for initiator binding might suffice to make methylation an essential function in V. cholerae. The structure of oriII suggests that it originated from a plasmid, but unlike plasmids, oriII makes use of methylation for once-per-cell-cycle replication, the norm for chromosomal but not plasmid replication.

  16. Exploring the effects of energy consumption on output per worker: A study of Albania, Bulgaria, Hungary and Romania

    International Nuclear Information System (INIS)

    Kumar, Ronald Ravinesh; Stauvermann, Peter Josef; Patel, Arvind; Kumar, Radika Devi

    2014-01-01

    In this article, we explore the long-run cointegration between output, capital and energy consumption, in per worker terms, for Albania, Bulgaria, Hungary and Romania. We use the augmented Solow (1956) model and the ARDL bounds procedure (Pesaran et al., 2001) to examine the short-run and long-run effects of energy and capital on output (in per worker terms). We also conduct causality test using the Toda and Yamamoto (1995) non-causality procedure. Our results show the existence of long-run cointegration between output per worker and energy per worker for all the four countries. We find that energy per worker have a dynamic short-run positive effect in Albania (0.37%), Bulgaria (0.25%), Hungary (0.36%) and Romania (0.68%), and a long-run positive effect in Bulgaria (0.32%) and Romania (0.63%) which duly indicate that energy consumption has a momentous long-run effect in these two countries. The causality results indicate a unidirectional causation from output per worker to energy per worker for all the four countries, and from capital per worker to energy per worker for Albania and Romania. Consequently, a balance between effective energy consumption and sound energy conservation policies are likely to support economic growth in the four countries. - Highlights: • Energy has a short-run positive effect in Albania, Bulgaria, Hungary and Romania. • A long-run positive elasticity is noted in Bulgaria and Romania. • Output per worker cause energy per worker in the four countries. • A unidirectional causality from capital to energy is noted for Albania and Romania

  17. A parts-per-billion measurement of the antiproton magnetic moment.

    Science.gov (United States)

    Smorra, C; Sellner, S; Borchert, M J; Harrington, J A; Higuchi, T; Nagahama, H; Tanaka, T; Mooser, A; Schneider, G; Bohman, M; Blaum, K; Matsuda, Y; Ospelkaus, C; Quint, W; Walz, J; Yamazaki, Y; Ulmer, S

    2017-10-18

    Precise comparisons of the fundamental properties of matter-antimatter conjugates provide sensitive tests of charge-parity-time (CPT) invariance, which is an important symmetry that rests on basic assumptions of the standard model of particle physics. Experiments on mesons, leptons and baryons have compared different properties of matter-antimatter conjugates with fractional uncertainties at the parts-per-billion level or better. One specific quantity, however, has so far only been known to a fractional uncertainty at the parts-per-million level: the magnetic moment of the antiproton, . The extraordinary difficulty in measuring with high precision is caused by its intrinsic smallness; for example, it is 660 times smaller than the magnetic moment of the positron. Here we report a high-precision measurement of in units of the nuclear magneton μ N with a fractional precision of 1.5 parts per billion (68% confidence level). We use a two-particle spectroscopy method in an advanced cryogenic multi-Penning trap system. Our result  = -2.7928473441(42)μ N (where the number in parentheses represents the 68% confidence interval on the last digits of the value) improves the precision of the previous best measurement by a factor of approximately 350. The measured value is consistent with the proton magnetic moment, μ p  = 2.792847350(9)μ N , and is in agreement with CPT invariance. Consequently, this measurement constrains the magnitude of certain CPT-violating effects to below 1.8 × 10 -24 gigaelectronvolts, and a possible splitting of the proton-antiproton magnetic moments by CPT-odd dimension-five interactions to below 6 × 10 -12 Bohr magnetons.

  18. Deteção de anomalias em modelos de publicidade Pay-Per-Click

    OpenAIRE

    Lopes, Eduardo Luís da Silva

    2012-01-01

    Dissertação de mestrado em Engenharia Informática Nowadays, online advertisement is one of the most effective and profitable marketing strategies. An example of strong growth in online advertisement is the Pay-Per-Click Advertising Model where all parties are benefited. Due to the number of stakeholders and the amount of money involved, it is inevitable to find efficient methods to analyse the validity of clicks on online advertising, specifically in Pay-Per-Click. The co...

  19. Unified Probabilistic Models for Face Recognition from a Single Example Image per Person

    Institute of Scientific and Technical Information of China (English)

    Pin Liao; Li Shen

    2004-01-01

    This paper presents a new technique of unified probabilistic models for face recognition from only one single example image per person. The unified models, trained on an obtained training set with multiple samples per person, are used to recognize facial images from another disjoint database with a single sample per person. Variations between facial images are modeled as two unified probabilistic models: within-class variations and between-class variations. Gaussian Mixture Models are used to approximate the distributions of the two variations and exploit a classifier combination method to improve the performance. Extensive experimental results on the ORL face database and the authors' database (the ICT-JDL database) including totally 1,750facial images of 350 individuals demonstrate that the proposed technique, compared with traditional eigenface method and some well-known traditional algorithms, is a significantly more effective and robust approach for face recognition.

  20. Analysis of per capita income dynamics of the USA and Russia gross domestic product

    Directory of Open Access Journals (Sweden)

    Igor' Il'ich Pichurin

    2012-09-01

    Full Text Available This paper represents a judgment that the relator of per capita income of the countries is a rough indicator of the ratio of labor productivity in these countries. Accordingly, the analysis of the dynamics of per capita income in the United States and Russia for the period from 1861 to present time is made. The described statistical data shows that the ratio of per capita income in the U. S. and Russia has not changed from 1861 to 1913. Consequently, the nowadays widespread claim that capitalist development in Russia led the country into the category of rapidly developing countries for 50 years after the abolition of serfdom is not true. The gap in labor productivity in Russia compared to the United States, Germany, Britain and other developed countries remained unchanged. The sharp decline in per capita income was based on the country's industrialization and appropriate agricultural sphere mechanization. As a result, the gap has narrowed to the mid-sixties of the XX century up to two times, despite the fact those ten years of this period fell out from the normal development in connection with the Second World War and post-war reconstruction of the nationaleconomy. After thecollapse of thesocialisteconomy, this gap increased up to fivetimes in 2000, and now after the first decade of the XXI century it is about threetimes. Thereasons for these changes in respect to per capita income are analyzed in this paper.

  1. Husserl and Kant on Persönlichkeit

    Directory of Open Access Journals (Sweden)

    James Dodd

    2011-03-01

    Full Text Available This paper pursues a Kantian critique of Husserl’s theory of moral consciousness as it is found in his lectures on ethics and other shorter pieces on political and moral philosophy from the interwar period. The critique centers on Kant’s conception of moral personality (Persönlichkeit, arguing that Husserl fails to appreciate the force of this idea, subsequently leaving himself open to the charge of moral perfectionism. The paper ends with a positive assessment of Husserl’s thought, however, arguing that Husserl provides important resources for understanding moral consciousness as a sensibility for the possible, adding an important dimension to approaches in ethics that tend to center exclusively on questions of motivation and principle.   

  2. Valerianaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Valerianaceae es reconocida en el Perú por presentar seis géneros y 92 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, principalmente hierbas y subarbustos. En este trabajo reconocemos 41 especies y dos variedades como endemismos, representando cinco géneros, de los cuales Valeriana es el género más rico en especies endémicas. Los endemismos han sido encontrados principalmente en las regiones Puna Húmeda y Seca, Mesoandina y Altoandina, entre los 2700 y 5200 m de altitud. Se aplicaron las categorías y criterios de la UICN a 16 endemismos. Aparentemente, 14 taxones han sido registrados dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  3. Liliaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Liliaceae es reconocida en el Perú con 15 géneros (excepto Alstroemeria y Bomarea y aproximadamente 29 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, todas ellas hierbas. Esta familia incluye tres géneros endémicos, Diamena, Diora y Trichlora. En este trabajo reconocemos 11 especies endémicas en cinco géneros. Se asignó las categorías de amenaza de la UICN a seis especies. La mitad de los endemismos es conocido solamente de una localidad. Los taxones endémicos ocupan las regiones del Desierto Semicálido Costero y Mesoandina, entre los 600 y 3600 m de altitud. Solamente una especie está representada en un área natural protegida.

  4. Thevetia neriifolia Juss. ex Steud Syn. J. peruviava (Pers.) Schum ...

    Indian Academy of Sciences (India)

    Thevetia neriifolia Juss. ex Steud Syn. J. peruviava (Pers.) Schum (English: yellow oleander; Hindi: Pili-. Kaner) of Apocynaceae is a small evergreen ornamental tree with strap-like simple leaves and funnel- shaped yellow flowers. Fruit is large with a single hard-shelled seed. Thevetia trees are largely cultivated in gardens ...

  5. A Systematic Review of Cost-Effectiveness Studies Reporting Cost-per-DALY Averted.

    Directory of Open Access Journals (Sweden)

    Peter J Neumann

    Full Text Available Calculating the cost per disability-adjusted life years (DALYs averted associated with interventions is an increasing popular means of assessing the cost-effectiveness of strategies to improve population health. However, there has been no systematic attempt to characterize the literature and its evolution.We conducted a systematic review of cost-effectiveness studies reporting cost-per-DALY averted from 2000 through 2015. We developed the Global Health Cost-Effectiveness Analysis (GHCEA Registry, a repository of English-language cost-per-DALY averted studies indexed in PubMed. To identify candidate studies, we searched PubMed for articles with titles or abstracts containing the phrases "disability-adjusted" or "DALY". Two reviewers with training in health economics independently reviewed each article selected in our abstract review, gathering information using a standardized data collection form. We summarized descriptive characteristics on study methodology: e.g., intervention type, country of study, study funder, study perspective, along with methodological and reporting practices over two time periods: 2000-2009 and 2010-2015. We analyzed the types of costs included in analyses, the study quality on a scale from 1 (low to 7 (high, and examined the correlation between diseases researched and the burden of disease in different world regions.We identified 479 cost-per-DALY averted studies published from 2000 through 2015. Studies from Sub-Saharan Africa comprised the largest portion of published studies. The disease areas most commonly studied were communicable, maternal, neonatal, and nutritional disorders (67%, followed by non-communicable diseases (28%. A high proportion of studies evaluated primary prevention strategies (59%. Pharmaceutical interventions were commonly assessed (32% followed by immunizations (28%. Adherence to good practices for conducting and reporting cost-effectiveness analysis varied considerably. Studies mainly included

  6. Evaluating Drug Cost per Response with SGLT2 Inhibitors in Patients with Type 2 Diabetes Mellitus.

    Science.gov (United States)

    Lopez, Janice M S; Macomson, Brian; Ektare, Varun; Patel, Dipen; Botteman, Marc

    2015-09-01

    The sodium-glucose cotransporter 2 (SGLT2) inhibitors, which include canagliflozin, dapagliflozin, and empagliflozin, represent a new class of antihyperglycemic agents. Few studies have assessed their cost per response, with "cost per response" being the total cost of a select drug, divided by the resulting change in glycated hemoglobin (HbA1c) levels. To examine the drug cost of SGLT2 inhibitors per a reduction in placebo-adjusted 1% HbA1c in patients with type 2 diabetes mellitus who received treatment during 26 weeks with canagliflozin, dapagliflozin, or empagliflozin. The drug cost per response for each of the 3 agents individually was assessed based on data from a subset of clinical trials discussed in the prescribing information for each drug that were all placebo-controlled studies evaluating each drug as monotherapy, dual therapy (combined with metformin), and triple therapy (combined with metformin and a sulfonylurea) in patients with uncontrolled, type 2 diabetes mellitus. The US 2015 wholesale acquisition cost for each drug was used to calculate each drug's treatment costs over 26 weeks. The average cost per response for each drug was defined as the prescription drug cost of each SGLT2 inhibitor, divided by the average, placebo-adjusted HbA1c reduction at 26 weeks. The drug cost per unit dose was the same for canagliflozin (100 mg or 300 mg), dapagliflozin (5 mg or 10 mg), and empagliflozin (10 mg or 25 mg), at $11.43. The drug cost per placebo-adjusted 1% HbA1c reduction varied by agent and by dose, as a result of the differences in the treatment responses for each of the 3 drugs. The costs per response for canagliflozin 100 mg as monotherapy, dual therapy, and triple therapy regimens ranged from $2286 to $3355, and for canagliflozin 300 mg, from $1793 to $2702. The costs per response for dapagliflozin 5 mg as monotherapy and dual therapy (triple therapy was not available at the time of the study) ranged from $4161 to $5201; the cost for dapagliflozin

  7. VizieR Online Data Catalog: V873 Per BVR light curves (Kriwattanawong+, 2015)

    Science.gov (United States)

    Kriwattanawong, W.; Poojon, P.

    2015-07-01

    BVR photometric observations of V873 Per were carried out on the 0.5-m telescope at Sirindhorn Observatory, Chiang Mai University. The photometric data were taken during four nights (November 27-30, 2011), by using SBIG CCD (Model of ST10-XME), with exposure time of 90s. A total of 855 individual observations were obtained in three filter bands (285 observations per filter band). The IRAF package was used for data reduction and the BVR magnitude measurements. (1 data file).

  8. Effect of calving interval and parity on milk yield per feeding day in Danish commercial dairy herds.

    Science.gov (United States)

    Lehmann, J O; Fadel, J G; Mogensen, L; Kristensen, T; Gaillard, C; Kebreab, E

    2016-01-01

    The idea of managing cows for extended lactations rather than lactations of the traditional length of 1 yr primarily arose from observations of increasing problems with infertility and cows being dried off with high milk yields. However, it is vital for the success of extended lactation practices that cows are able to maintain milk yield per feeding day when the length of the calving interval (CInt) is increased. Milk yield per feeding day is defined as the cumulated lactation milk yield divided by the sum of days between 2 consecutive calvings. The main objective of this study was to investigate the milk production of cows managed for lactations of different lengths, and the primary aim was to investigate the relationship between CInt, parity, and milk yield. Five measurements of milk yield were used: energy-corrected milk (ECM) yield per feeding day, ECM yield per lactating day, cumulative ECM yield during the first 305 d of lactation, as well as ECM yield per day during early and late lactation. The analyses were based on a total of 1,379 completed lactations from cows calving between January 2007 and May 2013 in 4 Danish commercial dairy herds managed for extended lactation for several years. Herd-average CInt length ranged from 414 to 521 d. The herds had Holstein, Jersey, or crosses between Holstein, Jersey, and Red Danish cows with average milk yields ranging from 7,644 to 11,286 kg of ECM per cow per year. A significant effect of the CInt was noted on all 5 measurements of milk yield, and this effect interacted with parity for ECM per feeding day, ECM per lactating day and ECM per day during late lactation. The results showed that cows were at least able to produce equivalent ECM per feeding day with increasing CInt, and that first- and second-parity cows maintained ECM per lactating day. Cows with a CInt between 17 and 19 mo produced 476 kg of ECM more during the first 305 d compared with cows with a CInt of less than 13 mo. Furthermore, early

  9. A new species of Hyalella from the Andes in Perú (Crustacea: Amphipoda: Hyalellidae

    Directory of Open Access Journals (Sweden)

    Exequiel R González

    2002-06-01

    Full Text Available Hyalella pauperocavae n. sp. from Huancayo, Perú, is described. Five other epigean freshwater amphipods have been described from Peru (excluding Lake Titicaca, but the lack of type material and poor descriptions do not allow the assignment of the species described here to any of the names known for the areaSe describe la especie Hyalella pauperocavae n. sp. recolectada en la localidad de Huancayo, Perú. Otras cinco especies de anfípodos epígeos se conocen para el Perú (excluyendo aquellas presentes en el Lago Titicaca. La ausencia de material tipo y descripciones poco claras impidieron la asignación de la especie descrita aquí a alguno de los nombres conocidos para el área

  10. Criterion 6, indicator 28 : total and per capita consumption of wood and wood products in round wood equivalents

    Science.gov (United States)

    James L. Howard; Rebecca Westby; Kenneth E. Skog

    2010-01-01

    Total consumption of wood and paper products and fuelwood, in roundwood equivalents, increased between 1965 and 1988 from 13.2 to 18.9 billion cubic feet. Since 1988, it has been about 20 billion cubic feet per year. Total per capita consumption increased between 1965 and 1987, from 68 to 83 ft3 per year. Since 1987 through 2006, per capita...

  11. 77 FR 64430 - Federal Travel Regulation; Per Diem, Miscellaneous Amendments

    Science.gov (United States)

    2012-10-22

    ... (including potential economic, environmental, public health and safety effects, distributive impacts, and...'s per diem rate. 8. Section 301-11.29--Updating the web address for state tax exemption information..., Regulatory Planning and Review, dated September 30, 1993. This rule is not a major rule under 5 U.S.C. 804. D...

  12. Application of total care time and payment per unit time model for physician reimbursement for common general surgery operations.

    Science.gov (United States)

    Chatterjee, Abhishek; Holubar, Stefan D; Figy, Sean; Chen, Lilian; Montagne, Shirley A; Rosen, Joseph M; Desimone, Joseph P

    2012-06-01

    The relative value unit system relies on subjective measures of physician input in the care of patients. A payment per unit time model incorporates surgeon reimbursement to the total care time spent in the operating room, postoperative in-house, and clinic time to define payment per unit time. We aimed to compare common general surgery operations by using the total care time and payment per unit time method in order to demonstrate a more objective measurement for physician reimbursement. Average total physician payment per case was obtained for 5 outpatient operations and 4 inpatient operations in general surgery. Total care time was defined as the sum of operative time, 30 minutes per hospital day, and 30 minutes per office visit for each operation. Payment per unit time was calculated by dividing the physician reimbursement per case by the total care time. Total care time, physician payment per case, and payment per unit time for each type of operation demonstrated that an average payment per time spent for inpatient operations was $455.73 and slightly more at $467.51 for outpatient operations. Partial colectomy with primary anastomosis had the longest total care time (8.98 hours) and the least payment per unit time ($188.52). Laparoscopic gastric bypass had the highest payment per time ($707.30). The total care time and payment per unit time method can be used as an adjunct to compare reimbursement among different operations on an institutional level as well as on a national level. Although many operations have similar payment trends based on time spent by the surgeon, payment differences using this methodology are seen and may be in need of further review. Copyright © 2012 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

  13. Role of type II protein arginine methyltransferase 5 in the regulation of Circadian Per1 gene.

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    Jungtae Na

    Full Text Available Circadian clocks are the endogenous oscillators that regulate rhythmic physiological and behavioral changes to correspond to daily light-dark cycles. Molecular dissections have revealed that transcriptional feedback loops of the circadian clock genes drive the molecular oscillation, in which PER/CRY complexes inhibit the transcriptional activity of the CLOCK/BMAL1 heterodimer to constitute a negative feedback loop. In this study, we identified the type II protein arginine methyltransferase 5 (PRMT5 as an interacting molecule of CRY1. Although the Prmt5 gene was constitutively expressed, increased interaction of PRMT5 with CRY1 was observed when the Per1 gene was repressed both in synchronized mouse liver and NIH3T3 cells. Moreover, rhythmic recruitment of PRMT5 and CRY1 to the Per1 gene promoter was found to be associated with an increased level of histone H4R3 dimethylation and Per1 gene repression. Consistently, decreased histone H4R3 dimethylation and altered rhythmic Per1 gene expression were observed in Prmt5-depleted cells. Taken together, these findings provide an insight into the link between histone arginine methylation by PRMT5 and transcriptional regulation of the circadian Per1 gene.

  14. Geo Tools Android : eines geogràfiques per Android

    OpenAIRE

    Leiva Olmo, Javier

    2012-01-01

    En aquest treball es fa un anàlisi de l'aplicació OSMDroid i d'altres aplicacions i llibreries SIG rellevants per al sistema operatiu Android. En este trabajo se hace un análisis de la aplicación OSMDroid y otras aplicaciones y librerías SIG relevantes para el sistema operativo Android. In this project we analyze OSMDroid and other GIS applications and libraries relevant to the Android operating system.

  15. Management decisions based on the measurement of enterprise performance through “Earnings per share“ indicator

    Directory of Open Access Journals (Sweden)

    Victoria Bogdan

    2008-10-01

    Full Text Available Earnings per share indicator does not provide though the possibility to compare all the enterprises which compute it due to the difficulties in interpreting the differences noticed from one enterprise to another, differences which can result from the different number of shares issued by each of them and from the different categories of shares issued. The accounting policy of IASB regarding the determination and interpretation of earnings per share of the enterprise is implemented through IAS 33. The main objective of our paper has in view the description and exemplification of the computing model of the Earnings per share indicator.

  16. Highlighting micrographic structures of uranium alloys containing 0.5 to 10 per cent wt molybdenum

    International Nuclear Information System (INIS)

    Laniesse, J.; Bouleau, M.

    1959-02-01

    The authors report a study which aimed at determining for different uranium molybdenum alloys and with respect to their molybdenum content a polishing method which allows a relatively simple grain examination in the as-cast condition, an as perfect as possible resolution of eutectic decompositions, and the appropriate conditions to highlight structures (beta-alpha and gamma-alpha martensite transformations, beta phase retention and decomposition, transient structures, eutectoid decomposition, and so on). Alloys differ by their molybdenum content: from 0.5 to 1 per cent wt, 1.5 to 3 per cent wt, 5 to 10 per cent wt

  17. Purchasing and Using Personal Emergency Response Systems (PERS): how decisions are made by community-dwelling seniors in Canada.

    Science.gov (United States)

    McKenna, Alexandra C; Kloseck, Marita; Crilly, Richard; Polgar, Jan

    2015-07-11

    As the demographic of older people continues to grow, health services that support independence among community-dwelling seniors have become increasingly important. Personal Emergency Response Systems (PERS) are medical alert systems, designed to serve as a safety net for seniors living alone. Health care professionals often recommend that seniors in danger of falls or other medical emergencies obtain a PERS. The purpose of the study was to investigate the experience of seniors living with and using a PERS in their daily lives, using a qualitative grounded theory approach. Five focus groups and 10 semi-structured interviews, with a total of 30 participants, were completed using a grounded theory approach. All participants were PERS subscribers over the age of 80, living alone in a naturally occurring retirement community (NORC) with high health service utilization in a major urban centre in Ontario. Constant comparative analysis was used to develop themes and ultimately a model of why and how seniors obtain and use the PERS. Two core themes, unpredictability and decision-making around PERS activation, emerged as major features of the theoretical model. Being able to get help and the psychological value of PERS informed the context of living with a PERS. A number of theoretical conclusions related to unpredictability and the decision-making process around activating PERS were generated.

  18. DNA adenine methylation is required to replicate both Vibrio cholerae chromosomes once per cell cycle.

    Directory of Open Access Journals (Sweden)

    Gaëlle Demarre

    2010-05-01

    Full Text Available DNA adenine methylation is widely used to control many DNA transactions, including replication. In Escherichia coli, methylation serves to silence newly synthesized (hemimethylated sister origins. SeqA, a protein that binds to hemimethylated DNA, mediates the silencing, and this is necessary to restrict replication to once per cell cycle. The methylation, however, is not essential for replication initiation per se but appeared so when the origins (oriI and oriII of the two Vibrio cholerae chromosomes were used to drive plasmid replication in E. coli. Here we show that, as in the case of E. coli, methylation is not essential for oriI when it drives chromosomal replication and is needed for once-per-cell-cycle replication in a SeqA-dependent fashion. We found that oriII also needs SeqA for once-per-cell-cycle replication and, additionally, full methylation for efficient initiator binding. The requirement for initiator binding might suffice to make methylation an essential function in V. cholerae. The structure of oriII suggests that it originated from a plasmid, but unlike plasmids, oriII makes use of methylation for once-per-cell-cycle replication, the norm for chromosomal but not plasmid replication.

  19. International inequalities in per capita CO2 emissions: a decomposition methodology by Kaya factors

    International Nuclear Information System (INIS)

    Duro, J.A.; Universitat de Barcelona; Padilla, E.

    2006-01-01

    In this paper, we provide a methodology for decomposing international inequalities in per capita CO 2 emissions into Kaya (multiplicative) factors and two interaction terms. We use the Theil index of inequality and show that this decomposition methodology can be extended for analyzing between- and within-group inequality components. We can thus analyze the factors behind inequalities in per capita CO 2 emissions across countries, between groups of countries and within groups of countries. The empirical illustration for international data suggests some points. Firstly, international inequality in per capita CO 2 emissions is mainly attributable to inequalities in per capita income levels, which helps to explain its recent reduction, while differences in carbon intensity of energy and energy intensity have made a less significant contribution. This result is strongly influenced by the performance of China and India. Secondly, the between-group inequality component, which is the biggest component, is also largely explained by the income factor. Thirdly, the within-group inequality component increased slightly during the period, something mainly due to the change in the income factor and the interaction terms in a few regions. (author)

  20. Transición nutricional en el Perú, 1991 - 2005

    Directory of Open Access Journals (Sweden)

    Mónica L. Mispireta

    2007-04-01

    Full Text Available La transición nutricional es un proceso que incluye cambios en el perfil nutricional de las poblaciones. Muchos países en desarrollo, incluyendo Perú, se encuentran en transición. Objetivos: Describir la variación del perfil nutricional de los niños, madres en edad fértil y familias peruanas entre 1991 y 2005. Materiales y métodos: Usando la información disponible en las bases de datos de las Encuestas Nacionales Demográficas y de Salud realizadas en el Perú entre 1991 y 2005, se describe la prevalencia de malnutrición en niños menores de cinco años, madres en edad fértil y familias peruanas a nivel nacional, regional, y de acuerdo al nivel socioeconómico y área de residencia (urbano/rural. Resultados: La tasa de retardo de crecimiento infantil se ha mantenido alta y constante desde 1996. El sobrepeso infantil se ha incrementando principalmente en Lima Metropolitana y la Costa. En las madres en edad fértil el problema más importante es la alta prevalencia de sobrepeso y obesidad, que se incrementa principalmente en Lima Metropolitana y la Costa. La coexistencia de retardo de crecimiento infantil y obesidad materna a nivel familiar ha sido baja y sin presentar alguna tendencia temporal en el período estudiado. Conclusiones: El perfil nutricional peruano se encuentra en transición. Sus principales componentes son la alta tasa de retardo de crecimiento infantil y el incremento en sobrepeso y obesidad materna. Estos hallazgos muestran que la población peruana presenta un alto riesgo de desarrollar enfermedades asociadas con ambos extremos de la nutrición.