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Sample records for tephrosia toxicaria pers

  1. Chemical and biological study of Tephrosia toxicaria Pers; Estudo quimico e biologico de Tephrosia toxicaria Pers

    Energy Technology Data Exchange (ETDEWEB)

    Vasconcelos, Jackson Nunes e; Lima, Jefferson Queiroz; Lemos, Telma Leda Gomes de; Oliveira, Maria da Conceicao Ferreira de; Almeida, Maria Mozarina Beserra; Andrade-Neto, Manoel; Mafezoli, Jair; Arriaga, Angela Martha Campos; Braz-Filho, Raimundo [Universidade Federal do Ceara (UFC), Fortaleza, CE (Brazil). Dept. de Quimica Organica e Inorganica]. E-mail: angelamcarriaga@yahoo.com.br; Santiago, Gilvandete Maria Pinheiro [Universidade Federal do Ceara (UFC), Fortaleza, CE (Brazil). Faculdade de Farmacia, Odontologia e Enfermagem. Dept. de Farmacia

    2009-07-01

    The ethanol extracts from leaves, stems, pods and roots were assayed against the third instar Aedes aegypti larvae and the highest activity was observed in the roots extracts (LC{sub 50} 47.86 ppm). This extract was submitted to partition with hexane, chloroform, ethyl acetate and methanol. The respective fractions were bioassayed and the best larvicidal activities were identified in the hexane (LC{sub 50} 23.99 ppm) and chloroform (LC{sub 50} 13.80 ppm) fractions. Antioxidant activity (DDPH method) was observed in the ethanol extract (IC{sub 50} 276 {mu}g/mL) from roots of T. toxicaria. Fractions from this extract were also tested and the highest antioxidant activity (IC{sub 50} 89 {mu}g/mL) was found in the methanol fraction. The flavonoids iso-obovatin (1), obovatin (2), 6a,12a-dehydro-{beta}-toxicarol (3), 6a,12a-dehydro-{alpha}-toxicarol (4) and {alpha}-toxicarol (5) were isolated and bioassayed against A. aegypti. The flavonoid 5 showed the best larvicidal activity (LC{sub 50} 24.55 ppm). The antioxidant activity of 2 was investigated and showed IC{sub 50} 3.370 {mu}g/ml. The antioxidant and larvicidal activities of Tephrosia toxicaria are reported for the first time. (author)

  2. Pharmacognostical Standardization of Tephrosia purpurea Pers Root

    Science.gov (United States)

    Sandhya, S.; Ventaka, Ramana K.; Vinod, K.R

    2010-01-01

    Wild Indigo or Purple Tephrosia or fish poison occurs throughout the Indian subcontinent. It is widely used in the treatment of inflammation, diabetes, rheumatism, asthma, diarrhoea and many other ailments. But so far the pharmacognostic standardization has not been reported for its proper identification. Hence the present study is a pharmacognosy work carried out for the root part. This may help in the identification of the plant species. A thin transverse section, powder microscopy, measurement of the dimensions of cell structures, fluorescence analysis and physico chemical parameters were conducted for the root. From the TS, the secondary xylem fibres and vessels were found to be the tissues of diagnostic importance. The xylem vessels were of two types: narrow and long; broad and short. The important characters in the powdered microscopy were vessel elements, fibres and xylem parenchyma cells. The different fluorescent light shades were obtained under short and long UV light for both powder as well as the extracts of the root. The proximate analysis values were also obtained in a satisfactory way. Combining all these data a suitable root profile for plant can be constructed which may help in the identification of quality of the plant part. PMID:22557415

  3. Revisão taxonômica das espécies do gênero Tephrosia Pers. (Leguminosae, Papilionoideae, Millettieae) ocorrentes na América do Sul

    OpenAIRE

    Rubens Teixeira de Queiroz

    2012-01-01

    Resumo: Tephrosia Pers. apresenta distribuição pantropical e é constituído por cerca de 350 espécies. A classificação infragenérica foi baseada principalmente em características florais das espécies. Para o gênero, têm sido reconhecidos dois subgêneros: Tephrosia subg.BarbistylaBrummitt e T. subg. Tephrosia, sendo o primeiro caracterizado pela presença de indumento ao longo do estilete e a base do estigma glabra, enquanto o segundo apresenta estilete glabro e tricomas na base do estigma. Ambo...

  4. PHARMACOBOTANICAL STUDIES ON ‘SHVET SHARPUNKHA’ – A COMPARATIVE DIAGNOSTIC ACCOUNT OF TEPHROSIA VILLOSA PERS. AND T. PURPUREA (LINN.) PERS. FORM ALBIFLORA S. R. PAUL et. R. C. GUPTA

    Science.gov (United States)

    Gupta, R. C.

    1988-01-01

    Two kinds of ‘shapunkha’, the ‘Shvet’ (white) and ‘Rakta’ (red) are described in some of the Ayurvedic texts and the former is reported therapeutically more effective. Some of the Ayurvedic physicians use T. villosa Pers. as ‘Shvet sharpunkha’ due to its persistently villous silky white parts. While others have advocated white colour of flowers as main feature for distinguishing “Shvet sharpunkha’. A white flowered form of Tephrosia purpurea which is found in association with red or purple flowered ones is reported by us as T. purpurea (Linn.) Pers. Form albiflora S. R. Paul et R. C. Gupta. In the present work, however, detailed comparative pharmacognosy of all vegetable parts of T. villosa and T. purpurea f. albiflora have been carried out. Also the study reveals that two species exhibit great similarity in their macro – an microscopical feature. PMID:22557616

  5. Assessment of effect of ethanolic extract of Tephrosia purpurea (L. Pers., Fabaceae, activity on lithium-pilocarpine induced Status epilepticus and oxidative stress in Wistar rats Avaliação do efeito do extrato etanólico da Tephrosia purpurea (L. Pers., Fabaceae, sobre o status epilepticus induzido por lítio-pilocarpina e estresse oxidativo, em ratos Wistar

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    G Asuntha

    2010-11-01

    Full Text Available Tephrosia purpurea (L. Pers., Fabaceae, is claimed to be of use in the control and treatment of a variety of epileptic disorders in Indian system of medicine. The present study plans to systematically evaluate T. purpurea and to verify this claim. Status epilepticus was induced in male albino rats of Wistar strain by administration of pilocarpine (30 mg/kg, i.p. 24 h after lithium chloride (3 mEq/kg, i.p.. Different doses of the extract of T. purpurea were administered orally one hour before the injection of pilocarpine. The severity of status epilepticus was observed and recorded every 15 min till 90 min and thereafter every 30 min till 180 min, using the scoring system. The in vivo lipid peroxidation of rat brain tissue was measured. The in vitro NO free radical scavenging activity of plant extract was assessed. The interaction between plant extract and 2-diphenyl-2-picryl hydrazyl (DPPH was also observed for in vitro free radical scavenging activity. The severity of status epilepticus was reduced with the administration of ethanolic extract of T. purpurea. Ethanolic extract of the plant exhibited both in vivo and in vitro antioxidant activity. The ethanolic extract of T. purpurea was found to be useful to control lithium-pilocarpine induced status epilepticus in albino rats of Wistar strain.Tephrosia purpurea (L. Pers., Fabaceae, é conhecida pelo seu uso no controle e tratamento de uma variedade de distúrbios epilépticos no sistema indiano de medicina. O presente estudo pretende avaliar de forma sistemática T. purpurea e verificar essa alegação. Status epilepticus foi induzido em ratos albinos machos da linhagem Wistar pela administração de pilocarpina (30 mg/kg, i.p. 24 h após o cloreto de lítio (3 mEq/kg, i.p.. Diferentes doses do extrato de T. purpurea foram administrados por via oral uma hora antes da injeção de pilocarpina. A gravidade do status epilepticus foi observada e registrada a cada 15 min até 90 min e

  6. Preliminary Investigation Into The Acute Oral Toxicity Of Tephrosia ...

    African Journals Online (AJOL)

    An investigation was carried out on the acute toxicity of the crude methanolic leaf extract of Tephrosia vogelii Hook. f. (Fabaceae) in mice following oral administration of the extract at doses ranging from 10 to 10,000 mg per kg body weight. Propylene glycol was used as vehicle of administration. Clinical signs observed ...

  7. Natural products from the genus tephrosia.

    Science.gov (United States)

    Chen, Yinning; Yan, Tao; Gao, Chenghai; Cao, Wenhao; Huang, Riming

    2014-01-27

    The genus Tephrosia, belonging to the Leguminosae family, is a large pantropical genus of more than 350 species, many of which have important traditional uses in agriculture. This review not only outlines the source, chemistry and biological evaluations of natural products from the genus Tephrosia worldwide that have appeared in literature from 1910 to December 2013, but also covers work related to proposed biosynthetic pathways and synthesis of some natural products from the genus Tephrosia, with 105 citations and 168 new compounds.

  8. Cytotoxic cardiac glycosides and coumarins from Antiaris toxicaria.

    Science.gov (United States)

    Shi, Li-Shian; Kuo, Sheng-Chu; Sun, Han-Dong; Morris-Natschke, Susan L; Lee, Kuo-Hsiung; Wu, Tian-Shung

    2014-03-15

    Eight new cardiac glycosides/aglycones (antiaritoxiosides A-G, 1-7, and antiarotoxinin B, 8), two new coumarins (anticarins A-B, 41-42), and two new flavanones (antiarones L-K, 43-44) were isolated from trunk bark of Antiaris toxicaria together with 53 known compounds. The new structures were established by extensive analysis of spectroscopic data. Compound 1 (10-carboxy and 3α-hydroxy) and compounds 3-6 (10-hydroxy) contain unique substituents that are rarely found in cardiac glycosides. The cytotoxic effects of isolated compounds against ten human cancer cell lines, KB, KB-VIN, A549, MCF-7, U-87-MG, PC-3, 1A9, CAKI-1, HCT-9 and S-KMEL-2, were tested using the sulforhodamine B assay. Five compounds (12, 16, 20, 22, and 31) showed significant cytotoxicity against all ten cancer cell lines, with notable potency at the ng/mL level against some cell lines, which merits further development as clinical trial candidates. Copyright © 2014. Published by Elsevier Ltd.

  9. Anticonvulsant effects of antiaris toxicaria aqueous extract: investigation using animal models of temporal lobe epilepsy.

    Science.gov (United States)

    Mante, Priscilla Kolibea; Adongo, Donatus Wewura; Woode, Eric

    2017-04-26

    Antiaris toxicaria has previously shown anticonvulsant activity in acute animal models of epilepsy. The aqueous extract (AAE) was further investigated for activity in kindling with pentylenetetrazole and administration of pilocarpine and kainic acid which mimic temporal lobe epilepsy in various animal species. ICR mice and Sprague-Dawley rats were pre-treated with AAE (200-800 mg kg(-1)) and convulsive episodes induced using pentylenetetrazole, pilocarpine and kainic acid. The potential of AAE to prevent or delay onset and alter duration of seizures were measured. In addition, damage to hippocampal cells was assessed in kainic acid-induced status epilepticus test. 800 mg kg(-1) of the extract suppressed the kindled seizure significantly (P toxicaria may be effective in controlling temporal lobe seizures in rodents.

  10. Antidepressant, anxiolytic, and anticataleptic effects of aqueous leaf extract of Antiaris toxicaria Lesch. (Moraceae) in mice: possible mechanisms of actions.

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    Agbaje, Esther O; Ishola, Ismail O; Oniyire, Joel A

    2014-02-27

    Abstract Background: The leaves of Antiaris toxicaria Lesch. (Moraceae) are used by traditional medicine practitioners in southwest Nigeria in the management of epilepsy, wounds, and neurological disorders. Hence, this study was undertaken to investigate the effect of the aqueous leaf extract of A. toxicaria on the central nervous system. Methods: One hour after administration of A. toxicaria [50-300 mg/kg orally (p.o.)], its antidepressant effect was evaluated using the forced swimming test (FST), anxiolytic effect using elevated plus maze (EPM) test, and anticataleptic effect using haloperidol-induced catalepsy, whereas its effects on hypnosis and motor coordination were studied using hexobarbitone-induced sleeping time and open-field tests, respectively, in mice. Results: Antiaris toxicaria (300 mg/kg) significantly increased swimming activity (36.88%) and reduced immobility time (38.54%). Pretreatment of mice with prazosin (an α1-adrenoceptor antagonist), sulpiride (a D2 receptor antagonist), and l-NG-nitro-arginine (nitric oxide synthase inhibitor) 15 min before A. toxicaria (300 mg/kg p.o.) treatment significantly prevented its antidepressant-like effect by 35.58%, 53.30%, and 56.11%, respectively, in the FST. However, pretreatment with metergoline (5-HT2 receptor antagonist), and atropine (muscarinic cholinergic antagonist) failed to reverse this effect. Interestingly, A. toxicaria (50 mg/kg) significantly increased open-arm exploration in the EPM by 70.31%, which was reversed by 82.66% in the presence of flumazenil [3 mg/kg intraperitoneally (i.p.)]. Haloperidol (1 mg/kg i.p.) induced cataleptic behavior in mice, which was reversed by A. toxicaria (300 mg/kg) (ptoxicaria possesses an antidepressant-like effect involving interaction with α1-adrenoceptor, D2 dopamine receptor, and nitrergic pathway; an anxiolytic-like effect linked to the benzodiazepine system; and a neuroprotective effect.

  11. Antinociceptive Effect of Tephrosia sinapou Extract in the Acetic Acid, Phenyl-p-benzoquinone, Formalin, and Complete Freund’s Adjuvant Models of Overt Pain-Like Behavior in Mice

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    Renata M. Martinez

    2016-01-01

    Full Text Available Tephrosia toxicaria, which is currently known as Tephrosia sinapou (Buc’hoz A. Chev. (Fabaceae, is a source of compounds such as flavonoids. T. sinapou has been used in Amazonian countries traditional medicine to alleviate pain and inflammation. The purpose of this study was to evaluate the analgesic effects of T. sinapou ethyl acetate extract in overt pain-like behavior models in mice by using writhing response and flinching/licking tests. We demonstrated in this study that T. sinapou extract inhibited, in a dose (1–100 mg/kg dependent manner, acetic acid- and phenyl-p-benzoquinone- (PBQ- induced writhing response. Furthermore, it was active via intraperitoneal, subcutaneous, and peroral routes of administration. T. sinapou extract also inhibited formalin- and complete Freund’s adjuvant- (CFA- induced flinching/licking at 100 mg/kg dose. In conclusion, these findings demonstrate that T. sinapou ethyl acetate extract reduces inflammatory pain in the acetic acid, PBQ, formalin, and CFA models of overt pain-like behavior. Therefore, the potential of analgesic activity of T. sinapou indicates that it deserves further investigation.

  12. Contraction Of Isolated Guinea Pig Ileum By Tephrosia vogelii Extract

    African Journals Online (AJOL)

    An investigation was carried out on the isolated guinea pig ileum, using the crude methanolic leaf extract of Tephrosia vogelii Hook. f., and with the aim of determining its effects on contraction of intestinal smooth muscle. Modified Magnus technique was employed in setting up the tissue. Acetylcholine (ACh), histamine and ...

  13. Agroforestry systems in northern Vietnam with Tephrosia candida as an alternative to short-fallow crop rotations

    Energy Technology Data Exchange (ETDEWEB)

    Hoang Fagerstroem, M.H. [Swedish Univ. of Agricultural Sciences, Uppsala (Sweden). Dept. of Soil Sciences

    2000-07-01

    Tephrosia candida was experimentally tested on-farm as an improved fallow species (TepFa), in hedgerows, (TepAl) and in a mulch transfer system (TepMu) in an upland rice (Oryza sativa) system on sloping land in northern Vietnam during the period 1996-1999. The objectives of this study were: (1) to investigate whether the existing monocropping (Mono) and short-fallow crop rotations (NaFa) are sustainable systems with respect to soil erosion and concomitant nutrient losses; (2) to determine whether agroforestry systems with Tephrosia (TepFa, TepAl, TepMu) can improve nutrient cycling and nutrient balances, for instance by preventing nutrient losses through erosion, as well as sustaining upland rice yields. A criteria system, including soil and nutrient losses, nutrient balances, changes of P-available pools, returns on labour and farmers' response, was used for comparing the systems tested. Only TepFa gave a positive input-output balance for both P and N. TepFa increased soil N and seemed to positively affect the release of soil labile P. However, the cost of Tephrosia seeds made the Net Present Value (NPV) of the Tephrosia fallow crop rotation system negative. TepMu increased upland rice yield by 50% compared to Mono. As a result, NPV was positive and sufficient rice for one more person could be produced per ha and year. However, the yield increase could cause a depletion of plant-available P, and the timing for pruning and mulching activities coincided with the farming activities in paddy fields. TepAl increased soil N, gave a neutral overall effect on crop yield but a negative NPV. NaFa gave a positive and highest NPV. In general, TepFa and TepMu were shown to increase crop yield per hectare with acceptable returns on labour and also to do better than Mono and NaFa with respect to preventing soil and nutrient losses through erosion. Recommendations are made for further research to focus on alternatives to maintain soil P, mechanisms of P pool reallocation and

  14. Phytochemical analysis of Tephrosia vogelii (fish poison bean ...

    African Journals Online (AJOL)

    This work was carried out to determine the chemical constituents of Tephrosia vogelii (Fish poison bean), in order to test the extracts of the plant for use as fish tranquilizer. Fresh samples of T. vogelii were collected separately, air-dried for 21 days and oven-dried at 60o C for 3-4 hours to constant weight. The dried samples ...

  15. In Vitro effect of the ethanolic extract of Tephrosia Vogelii on Rhipicephalus Sanguineus in Abomey-Calavi

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    Dougnon Tossou Jacques

    2015-04-01

    Full Text Available Objectives: Ticks are vectors of several diseases, of which many are zoonosis transmissible to humans. The use of Tephrosia leafs’ extract as a low cost acaricide is spreading among farmers in central Kenya. Materials and Methods: The present study’s aim is to inventory endogenous control methods against dogs’ ticks among which Rhipicephalus sanguineus, in the Municipality of Abomey-Calavi. From September to October 2013, a survey was made on forty randomly selected breeders and ticks samples were collected on forty dogs. The web platform, www.epicollect.net, was used for the survey. In total, 77.5% (n=40 of examined dogs were infested with ticks Results: Three species of ticks were identified: Rhipicephalus sanguineus, Haemaphysalis leachi, and Amblyomma variegatum. They were found on 77.5%, 17.5%, and 15% of examined dogs, respectively. The numerical abundance of the three species was 87.06%, 11.9%, and 1.03%, respectively. The average number of ticks per animal was 16.83±5.04, 2.3±1.64, and 0.2±0.08 for Rhipicephalus sanguineus, Haemaphysalis leachi, and Amblyomma variegatum, respectively. Farmers used manual diptank (67.5%, plant ash (37.5%, petroleum (12.5%, motor oil (2.50 %, and sea water (7.5% to fight against ticks. Conclusions: The phytochemical screening of the leafy stem’s powder of Tephrosia vogelii revealed the presence of catechol tannins, saponins, sugars, leuco-anthocyanins, polyterpenes, and sterols. A 100% larval mortality was observed at the concentration of 20% the ethanolic extract of the leafy stem of Tephrosia vogelii. The LC50 of this ethanolic extract against Rhipicephalus sanguineus larvae was equal to 2.6%.

  16. Tephrosia vogelii for control of fleas in free-range poultry

    African Journals Online (AJOL)

    ACSS

    2Programme Director International Animal Health, Center for Tropical Veterinary Medicine, Royal. School of Veterinary ... alternative for controlling diseases in rural areas, where access to modern medicines and extension service delivery is lacking. .... included: Tephrosia vogelii (fish bean),. Capsicum frutescens and ...

  17. Utilization of Tephrosia vogelii in controlling ticks in dairy cows by ...

    African Journals Online (AJOL)

    The study sought to evaluate the effectiveness of Tephrosia vogelii in controlling ticks on dairy cows among small-scale dairy farmers in Mashonaland Central Province of Zimbabwe. T. vogelii treatment concentrations and Triatix D acaricide dip were randomly administered to 40 dairy cows. The experiment was carried out ...

  18. Ethno-medical and veterinary uses of Tephrosia vogelii hook. F.: a ...

    African Journals Online (AJOL)

    All parts of Tephrosia vogelii Hook. f. (Fabaceae) is used in tropical Africa for numerous ethno-medical and traditional veterinary practices. The leaf is ichthyotoxic and has been used as insecticide, rodenticide and anthelminthic. It has also been used as abortifacient and to induce menses. The leaf macerate is purgative and ...

  19. Managing Tephrosia mulch and fertilizer to enhance coffee productivity on smallholder farms in the Eastern African Highlands

    NARCIS (Netherlands)

    Bucagu, C.; Vanlauwe, B.; Giller, K.E.

    2013-01-01

    In Maraba, Southwest Rwanda, coffee productivity is constrained by poor soil fertility and lack of organic mulch. We investigated the potential to produce mulch by growing Tephrosia vogelii either intercropped with smallholder coffee or in arable fields o

  20. Chemical constituents of essential oils of Tephrosia purpurea and Ipomoea carnea and their repellent activity against Odoiporus longicollis

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    Sahayaraj Kitherian

    2015-01-01

    Full Text Available Chemical constituents of essential oils (EOs obtained from stem and root of Tephrosia purpurea (Linn. Pers. and Ipomoea carnea Jacq. were investigated by Gas Chromatography-Mass Spectrometry (GC-MS. Total lipid and oil content was high in the stem than the root of T. purpurea and I. carnea. Essential oils extracted from the stem and root of T. purpurea and I. carnea showed 9 and 8 compounds respectively. Hexadecanoic acid was found to be the principal constituent of stem (69.61% and root (46.97% of T. purpurea while 70.61and 88.89% for stem and root, respectively in the case of I. carnea. The findings of the present study suggest that T. purpurea and I. carnea EOs can be used as a source of hexadecanoic acid which could be used for industrial purposes. The essential oils of T. purpurea and I. carnea showed strong repellent activity for males (-0.73 and -0.70 for T. purpurea and I. carnea stem EO respectively than females (-0.63 and -0.59 for T. purpurea and I. carnea stem EO respectively against banana pseudostem weevil Odoiporus longicollis. The results indicated that the active compounds of essential oils from stems of T. purpurea and I. carnea can be explored as natural repellents for control of Odoiporus longicollis.

  1. Phylogenetic Diversity and Antifungal Activity of Endophytic Fungi Associated with Tephrosia purpurea

    Science.gov (United States)

    Luo, Ze-Ping; Lin, Hai-Yan; Ding, Wen-Bing; He, Hua-Liang

    2015-01-01

    Sixty-one endophytic fungus strains with different colony morphologies were isolated from the leaves, stems and roots of Tephrosia purpurea with colonization rates of 66.95%, 37.50%, and 26.92%, respectively. Based on internal transcribed spacer sequence analysis, 61 isolates were classified into 16 genera belonging to 3 classes under the phylum Ascomycota. Of the 61 isolates, 6 (9.84%) exhibited antifungal activity against one or more indicator plant pathogenic fungi according to the dual culture test. Isolate TPL25 had the broadest antifungal spectrum of activity, and isolate TPL35 was active against 5 plant pathogenic fungi. Furthermore, culture filtrates of TPL25 and TPL35 exhibited greater than 80% growth inhibition against Sclerotinia sclerotiorum. We conclude that the endophytic fungal strains TPL25 and TPL35 are promising sources of bioactive compounds. PMID:26839503

  2. Antihyperglycemic and antilipidperoxidative effects ofTephrosia purpurea seed extract in streptozotocin induced diabetic rats.

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    Pavana, P; Sethupathy, S; Manoharan, S

    2007-03-01

    The aim of the present study was to evaluate the antihyperglycemic and antilipidperoxidative effects of ethanolic seed extract ofTephrosia purpurea (TpEt) in streptozotocin induced diabetic rats. Hyperglycemia associated with an altered hexokinase and glucose 6 phosphatase activities, elevated lipid peroxidation, disturbed enzymatic and non-enzymatic antioxidants status were observed in streptozotocin induced diabetic rats. Oral administration of "TpEt" at a dose of 300mg/kg bw showed significant antihyperglcemic and antilipidperoxidative effects as well as increased the activities of enzymatic antioxidants and levels of non enzymatic antioxidants. We also noticed that the antihyperglycemic effect of plant drug (TpEt) was comparable to that of the reference drug glibenclamide. Our results clearly indicate that "TpEt" has potent antihyperglycemic and antilipidperoxidative effects in streptozotocin induced diabetic rats and therefore further studies are warranted to isolate and characterize the bioactive antidiabetic principles from "TpEt".

  3. Antihyperglycemic and antihyperlipidemic effects of Tephrosia purpurea leaf extract in streptozotocin induced diabetic rats.

    Science.gov (United States)

    Pavana, P; Manoharan, S; Renju, G L; Sethupathy, S

    2007-10-01

    Diabetes mellitus is a worldwide leading metabolic syndrome, associated with profound alterations in carbohydrate, lipids, lipoproteins and protein metabolisms. Worldwide, traditional practitioners for the treatment of diabetes and its complications use a wide variety of medicinal plants. In the present study the aqueous extract of Tephrosia purpurea leaves (TpALet) was evaluated for its antihyperglycemic and antihyperlipidemic effects in streptozotocin induced diabetic rats. Profound alterations in the concentrations of blood glucose, lipids and lipoproteins were observed in diabetic rats. Oral administration of TpALet to diabetic rats at a dose of 600 mg/kg body weight significantly reduced the level of blood glucose and increased the level of plasma insulin as well as normalized the lipids and lipoproteins profile. The present study thus demonstrated that TpALet has prominent antihyperglycemic and antihyperlipidemic effects in streptozotocin induced diabetic rats.

  4. Larvicidal, antimicrobial and brine shrimp activities of extracts from Cissampelos mucronata and Tephrosia villosa from coast region, Tanzania

    Science.gov (United States)

    2011-01-01

    Background The leaves and roots of Cissampelos mucronata A. Rich (Menispermaceae) are widely used in the tropics and subtropics to manage various ailments such as gastro-intestinal complaints, menstrual problems, venereal diseases and malaria. In the Coast region, Tanzania, roots are used to treat wounds due to extraction of jigger. Leaves of Tephrosia villosa (L) Pers (Leguminosae) are reported to be used in the treatment of diabetes mellitus in India. In this study, extracts from the roots and aerial parts of C. mucronata and extracts from leaves, fruits, twigs and roots of T. villosa were evaluated for larvicidal activity, brine shrimps toxicity and antimicrobial activity. Methods Powdered materials from C. mucronata were extracted sequentially by dichloromethane followed by ethanol while materials from T.villosa were extracted by ethanol only. The extracts obtained were evaluated for larvicidal activity using Culex quinquefasciatus Say larvae, cytotoxicity using brine shrimp larvae and antimicrobial activity using bacteria and fungi. Results Extracts from aerial parts of C. Mucronata exhibited antibacterial activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Vibrio cholera, Bacillus anthracis, Streptococcus faecalis and antifungal activity against Candida albicans and Cryptococcus neoformans. They exhibited very low toxicity to brine shrimps and had no larvicidal activity. The root extracts exhibited good larvicidal activity but weak antimicrobial activity. The root dichloromethane extracts from C. mucronata was found to be more toxic with an LC50 value of 59.608 μg/mL while ethanolic extracts from root were not toxic with LC50>100 μg/mL). Ethanol extracts from fruits and roots of T. villosa were found to be very toxic with LC50 values of 9.690 μg/mL and 4.511 μg/mL, respectively, while, ethanol extracts from leaves and twigs of T. villosa were found to be non toxic (LC50>100 μg/mL). Conclusion These results

  5. Larvicidal, antimicrobial and brine shrimp activities of extracts from Cissampelos mucronata and Tephrosia villosa from coast region, Tanzania

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    Erasto Paul

    2011-04-01

    Full Text Available Abstract Background The leaves and roots of Cissampelos mucronata A. Rich (Menispermaceae are widely used in the tropics and subtropics to manage various ailments such as gastro-intestinal complaints, menstrual problems, venereal diseases and malaria. In the Coast region, Tanzania, roots are used to treat wounds due to extraction of jigger. Leaves of Tephrosia villosa (L Pers (Leguminosae are reported to be used in the treatment of diabetes mellitus in India. In this study, extracts from the roots and aerial parts of C. mucronata and extracts from leaves, fruits, twigs and roots of T. villosa were evaluated for larvicidal activity, brine shrimps toxicity and antimicrobial activity. Methods Powdered materials from C. mucronata were extracted sequentially by dichloromethane followed by ethanol while materials from T.villosa were extracted by ethanol only. The extracts obtained were evaluated for larvicidal activity using Culex quinquefasciatus Say larvae, cytotoxicity using brine shrimp larvae and antimicrobial activity using bacteria and fungi. Results Extracts from aerial parts of C. Mucronata exhibited antibacterial activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Vibrio cholera, Bacillus anthracis, Streptococcus faecalis and antifungal activity against Candida albicans and Cryptococcus neoformans. They exhibited very low toxicity to brine shrimps and had no larvicidal activity. The root extracts exhibited good larvicidal activity but weak antimicrobial activity. The root dichloromethane extracts from C. mucronata was found to be more toxic with an LC50 value of 59.608 μg/mL while ethanolic extracts from root were not toxic with LC50>100 μg/mL. Ethanol extracts from fruits and roots of T. villosa were found to be very toxic with LC50 values of 9.690 μg/mL and 4.511 μg/mL, respectively, while, ethanol extracts from leaves and twigs of T. villosa were found to be non toxic (LC50>100

  6. Biogenic nano-scale silver particles by Tephrosia purpurea leaf extract and their inborn antimicrobial activity

    Science.gov (United States)

    Ajitha, B.; Ashok Kumar Reddy, Y.; Reddy, P. Sreedhara

    2014-03-01

    In this paper we report the green synthesis of silver nanoparticles (Ag NPs) using Tephrosia purpurea leaf extract. The biomolecules present in the leaf extract are responsible for the formation of Ag NPs and they found to play dual role of both reducing as well as capping agents. The high crystallinity of Ag NPs is evident from bright circular spot array of SAED pattern and diffraction peaks in XRD profile. The synthesized Ag NPs are found to be nearly spherical ones with size approximately ∼20 nm. FTIR spectrum evidences the presence of different functional groups of biomolecules participated in encapsulating Ag NPs and the possible mechanism of Ag NPs formation was also suggested. Appearance of yellow color and surface plasmon resonance (SPR) peak at 425 nm confirms the Ag NPs formation. PL spectra showed decrement in luminescence intensity at higher excitation wavelengths. Antimicrobial activity of Ag NPs showed better inhibitory activity towards Pseudomonas spp. and Penicillium spp. compared to other test pathogens using standard Kirby-Bauer disc diffusion assay.

  7. Acute and subacute oral toxicity evaluation of Tephrosia purpurea extract in rodents

    Directory of Open Access Journals (Sweden)

    Talib Hussain

    2012-04-01

    Full Text Available Objective: To evaluate the acute and subacute toxicity of 50% ethanolic extract of Tephrosia purpurea (T. purpurea in rodents. Methods: The acute toxicity test was conducted in Swiss albino mice. The extract of T. purpurea was administrated in single doses of 50, 300 and 2000 mg/ kg and observed for behavioral changes and mortality, if any. In subacute toxicity study, Wistar rats of either sex were administered two doses of T. purpurea i.e., 200 and 400 mg/kg (One-tenth and one-fifth of the maximum tolerated dose, p.o. for 4 weeks. During 28 days of treatment, rats were observed weekly for any change in their body weight, food and water intake. At the end of 28 days, rats were sacrificed for hematological, biochemical and histopathology study. Results: In the acute toxicity study, T. purpurea was found to be well tolerated upto 2 000 mg/kg, produced neither mortality nor changes in behavior in mice. In subacute toxicity study, T. purpurea at dose level of 200 and 400 mg/kg did not produce any significant difference in their body weight, food and water intake when compared to vehicle treated rats. It also showed no significant alteration in hematological and biochemical parameters in experimental groups of rats apart from a decrease in aspartate transaminase, alanine transaminase and alkaline phosphate content at the dose of 400 mg/kg. Histopathological study revealed normal architecture of kidney and liver of T. purpurea treated rats. Conclusions: These results demonstrated that there is a wide margin of safety for the therapeutic use of T. purpurea and further corroborated the traditional use of this extract as an anti hepatocarcinogenic agent

  8. Six month-duration Tephrosia vogelii Hook.f. and Tithonia diversifolia (Hemsl.). A.Gray planted-fallows for improving maize production in Kenya

    NARCIS (Netherlands)

    Rutunga, V.; Karanja, N.K.; Gachene, C.K.K.

    2008-01-01

    An experiment including planted Tephrosia vogelii and Tithonia diversifolia fallow species and natural fallow was conducted at Maseno, Kenya, for assessing whether these fallows grown on a nutrient depleted land could produce sufficient green manure in six month period, whether their biomass

  9. Effects of Tephrosia purpurea aqueous seed extract on blood glucose and antioxidant enzyme activities in streptozotocin induced diabetic rats.

    Science.gov (United States)

    Pavana, P; Sethupathy, S; Santha, K; Manoharan, S

    2008-10-25

    The aim of the present study was to evaluate the effects of aqueous seed extract of Tephrosia purpurea (TpASet) on blood glucose and antioxidant status in streptozotocin induced diabetic rats. Hyperglycemia associated with an altered hexokinase and glucose-6-phosphatase activities, elevated lipid peroxidation, disturbed enzymatic [Superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)] and non enzymatic [Glutathione, vitamin C and vitamin E] antioxidant status were observed in streptozotocin induced diabetic rats. Oral administration of "TpASet" at a dose of 600 mg/kg body weight showed significant improvement in above mentioned parameters. Our results clearly indicate that "TpASet" has potent antihyperglycemic and antioxidant effects in streptozotocin-induced diabetic rats and therefore further studies are warranted to isolate and characterize the bioactive principles from "TpASet".

  10. Amendment of Tephrosia Improved Fallows with Inorganic Fertilizers Improves Soil Chemical Properties, N Uptake, and Maize Yield in Malawi

    Directory of Open Access Journals (Sweden)

    Maggie G. Munthali

    2014-01-01

    Full Text Available Maize production in Malawi is limited mainly by low soil N and P. Improved fallows of N-fixing legumes such as Tephrosia and Sesbania offer options for improving soil fertility particularly N supply. The interactions of Tephrosia fallows and inorganic fertilizers on soil properties, N uptake, and maize yields were evaluated at Chitedze Research Station in Malawi. The results indicated that the level of organic matter and pH increased in all the treatments except for the control. Total N remained almost unchanged while available P decreased in all plots amended with T. vogelii but increased in T. candida plots where inorganic P was applied. Exchangeable K increased in all the plots irrespective of the type of amendment. The interaction of N and P fertilizers with T. vogelii fallows significantly increased the grain yield. The treatment that received 45 kg N ha−1 and 20 kg P ha−1 produced significantly higher grain yields (6.8 t ha−1 than all the other treatments except where 68 kg N ha−1 and 30 kg P ha−1 were applied which gave 6.5 t ha−1 of maize grain. T. candida fallows alone or in combination with N and P fertilizers did not significantly affect grain yield. However, T. candida fallows alone can raise maize grain yield by 300% over the no-input control. Based on these results we conclude that high quality residues such as T. candida and T. vogelii can be used as sources of nutrients to improve crop yields and soil fertility in N-limited soils. However, inorganic P fertilizer is needed due to the low soil available P levels.

  11. Gangguan fisiologi dan biokimia Crocidolomia pavonana (F. (Lepidoptera: Crambidae akibat perlakuan ekstrak campuran Tephrosia vogelli dan Piper aduncum

    Directory of Open Access Journals (Sweden)

    Eka Chandra Lina

    2016-02-01

    Full Text Available Plant extracts have been known to cause physiological and biochemical interferences against insect, such as feeding inhibitor, food assimilation, and changes on activity of cytochrome b5 and cytochrome P450. This study was carried out to examine the effect of the extracts mixture of Tephrosia vogeliiand : Piper aduncum (1 : 5 on the physiology of Crocidolomia pavonana (F. as well as extract of P. aduncum on biochemical of C. pavonana. The study showed that larvae of C. pavonana was experiencing a feeding inhibition until 94.82% after treated with extracts mixture on concentration 0.06% or equivalent to LC95. However, larvae treated with extracts mixture on LC25 and LC50 only experienced a relative growth disorders as a result of intrinsic toxicity of extracts mixture which enters into the body of insects. Insect adaptation to toxic plant compounds indicated by an increase in the digestibility of larvae approximately 11.11%. Furthermore, detoxification mechanism by larvae against active compounds of P. aduncum occured and shown by an increase of oxidative enzyme activity of cytochrome b5 and cytochrome P450, in in vivo and in vitro compared to control. This study provides an information about mode of action of extracts mixture of T. vogelii and P. aduncum (1 : 5 on larvae of C. pavonana and detoxification mechanism by larvae due to extract of P. aduncum 

  12. Rotenoid content and in vitro acaricidal activity of Tephrosia vogelii leaf extract on the tick Rhipicephalus appendiculatus.

    Science.gov (United States)

    Kalume, M K; Losson, B; Angenot, L; Tits, M; Wauters, J N; Frédérich, M; Saegerman, C

    2012-11-23

    This study aimed to determine the rotenoid content of leaf extracts of the white (TVW) and purple (TVP) varieties of Tephrosia vogelii, both collected in North-Kivu Province, Democratic Republic of Congo and to evaluate their in vitro acaricidal efficacy on the tick Rhipicephalus appendiculatus. The high performance liquid chromatography analysis of rotenoid compounds from those extracts revealed that the contents of rotenone and deguelin were respectively higher in the leaves of TVW (0.044% and 1.13%) than in TVP (0.014% and 0.66%). Batches of 20 live adult ticks were immersed for 15 min in six different doses of each plant extract (0.625; 1.25; 2.5; 5; 10 and 20mg/mL of distilled water) and in the solution of Milbitraz(®) (12.5%m/v emulsifiable concentrate of amitraz) as a positive control. Additionally 9.5% ethanol and distilled water control groups were included. Tick mortalities were recorded every 24h for 5 days. The results indicated that there was no significant difference (P>0.05) between the acaricidal effect of Milbitraz(®) and the plant material used at a dose of at least 2.5 or 5mg/mL for TVW and TVP respectively. However, the dose response relationship determined at the fifth day after treatment showed a similar acaricidal effect for the two plant varieties with similar lethal dose 50 (LD(50)) of 0.83 and 0.81 mg/mL for TVW and TVP respectively. It is concluded that T. vogelii leaves may be used for the control of R. appendiculatus in areas where synthetic acaricides are either not available or affordable. However, T. vogelii extract should be sprayed in order to limit the potential risks of ecotoxicity linked to rotenoid compounds. Copyright © 2012 Elsevier B.V. All rights reserved.

  13. Toxic and antifeedant activities of prenylated flavonoids isolated from Tephrosia apollinea L. against three major coleopteran pests of stored grains with reference to their structure-activity relationship.

    Science.gov (United States)

    Nenaah, Gomah E

    2014-01-01

    Four prenylated flavonoids, isoglabratephrin, (+)-glabratephrin, tephroapollin-F and lanceolatin-A, were isolated from Tephrosia apollinea L. and tested against three stored grain insects. Using the filter paper bioassay, compounds showed adulticidal activity against Sitophilus oryzae (L), Rhyzopertha dominica (F) and Tribolium castaneum (Herbst) at concentrations of 0.875, 1.75 and 3.5 mg mL(- 1). At 3.5 mg mL(- 1), tephroapollin-F was the most toxic (78.6%, 64.6% and 60.7% mortality was recorded after 10 days exposure of S. oryzae, R. dominica and T. castaneum, respectively). The F1 progeny production of insects was affected after parental exposure to flavonoids, where S. oryzae was the most susceptible. A nutritional bioassay, employing a flour disc and test concentrations of 0.65, 1.3 and 2.6 mg g(- 1), revealed a significant reduction in the relative growth rate, relative consumption rate and efficiency of conversion of ingested food by all insects. The structure-activity relationship among the tested flavonoids was discussed.

  14. NopP, a phosphorylated effector of Rhizobium sp. strain NGR234, is a major determinant of nodulation of the tropical legumes Flemingia congesta and Tephrosia vogelii.

    Science.gov (United States)

    Skorpil, Peter; Saad, Maged M; Boukli, Nawal M; Kobayashi, Hajime; Ares-Orpel, Florencia; Broughton, William J; Deakin, William J

    2005-09-01

    Rhizobium sp. NGR234 nodulates many plants, some of which react to proteins secreted via a type three secretion system (T3SS) in a positive- (Flemingia congesta, Tephrosia vogelii) or negative- (Crotalaria juncea, Pachyrhizus tuberosus) manner. T3SSs are devices that Gram-negative bacteria use to inject effector proteins into the cytoplasm of eukaryotic cells. The only two rhizobial T3SS effector proteins characterized to date are NopL and NopP of NGR234. NopL can be phosphorylated by plant kinases and we show this to be true for NopP as well. Mutation of nopP leads to a dramatic reduction in nodule numbers on F. congesta and T. vogelii. Concomitant mutation of nopL and nopP further diminishes nodulation capacity to levels that, on T. vogelii, are lower than those produced by the T3SS null mutant NGR(Omega)rhcN. We also show that the T3SS of NGR234 secretes at least one additional effector, which remains to be identified. In other words, NGR234 secretes a cocktail of effectors, some of which have positive effects on nodulation of certain plants while others are perceived negatively and block nodulation. NopL and NopP are two components of this mix that extend the ability of NGR234 to nodulate certain legumes.

  15. Behavioural Responses of Heterobranchus longifilis Juveniles. Val (Pisces: 1840 Exposed to Freeze–dried Bark Extract of Tephrosia vogelii as an Anaesthetic

    Directory of Open Access Journals (Sweden)

    S.G. Solomon

    2014-03-01

    Full Text Available This study evaluates the anaesthetic properties of freeze-dried leaf extract of Tephrosia vogelii on the African catfish Heterobranchus longifilis juveniles. Experimental fish of Mean weight 115.00 were obtained from River Benue at Makurdi, Nigeria and acclimatized at the hatchery of University of Agriculture Makurdi for two weeks. Four H. longifilis were selected randomly for both control and treatment groups. Each treatment fish was weighed and injected intramuscularly 0.05ml of the extract at concentrations of 0.01, 0.02, 0.03, 0.04, 0.05 and 0.06g/l using a 2ml heparinized syringe. The result showed that H. longifilis in treatment group passed sequentially through the first three stages of anaesthesia but could not attain total loss of equilibrium (stage 4 of anaesthesia. The result showed that treatment group of fishes passed sequentially through the first three stages of anaesthesia but could not attain total loss of equilibrium (stage 4 of anaesthsia. Behavioural responses included mucus secretion, slow and erratic swimming, excrement discharge, increase in opercular beat rate, strong retention of reflex action, partial loss of equilibrium and colour change. The induction time showed a declining pattern with increasing concentration of the extract in the treatment levels with significant differences (P0.05. The most effective concentration was 0.06g/l with an induction time of 32.00±1.76 seconds and a recovery time of 182.00±3.46 minutes. The result of this study revealed that the freeze-dried bark extract of T. vogelii can be used as a tranquilizer for transporting fish over average distances, biopsy and morphological evaluation.

  16. Six month-duration Tephrosia vogelii Hook. f. and Tithonia diversifolia (Hemsl. A. Gray planted-fallows for improving maize production in Kenya

    Directory of Open Access Journals (Sweden)

    Gachene C.K.K.

    2008-01-01

    Full Text Available An experiment including planted Tephrosia vogelii and Tithonia diversifolia fallow species and natural fallow was conducted at Maseno, Kenya, for assessing whether these fallows grown on a nutrient depleted land could produce sufficient green manure in six month period, whether their biomass retained on the same plots or transferred to continuously cropped plots with or without added P fertiliser could increase yield of consecutive maize crops and whether it is useful to regularly repeat these fallows on same plots. First fallow was established in randomized complete blocks with three replicates. At harvesting, biomass was recorded, then either incorporated in situ or transferred to continuous cropped plots split with and without added P fertiliser and monitored for the effect in improving consecutive maize crops. The second fallow was managed on this split plot design. The two-planted shrubs fallows produced more than 9 Mg total dry biomass and accumulated 154 to 234 kg N.ha-1, which were significantly higher compared to the production in the natural fallow. The shrubs were also superior to natural fallow for P accumulation (5-22 kg versus 2 kg.ha-1. The aboveground dry biomass harvested from planted T. vogelii and T. diversifolia and either incorporated in situ or transferred into continuously cropped plots increased maize yields by 2.5 folds compared to the unmanured crop, the control. Supplementing the organic materials with an additional 20 kg P inorganic fertilizer increased the 1st maize yield by about 40%. Productivity in the plots with T. vogelii or T. diversifolia aboveground biomass removal was low for the subsequent fallow and maize crops when compared to the performance in plots where biomass was incorporated. To achieve sustained yields of maize in depleted soils requires regular improved fallowing at least one season alternating with one season maize, and additional P inputs.

  17. Il Raffrescamento per Ventilazione

    DEFF Research Database (Denmark)

    Perino, Marco; Heiselberg, Per Kvols

    2016-01-01

    edifici, si è iniziato a rivolgere un crescente interesse verso la ventilazione, specie naturale, quale strumento per il raffrescamento passivo degli edifici. Le recenti evoluzioni del quadro normativo e legislativo, infatti, hanno portato nel cor-so del tempo a costruire edifici sempre più isolati...... termicamente e sempre più a tenuta d'aria. Tali misure hanno consentito indubbiamente di ridurre la domanda energetica per il riscaldamento invernale, ma hanno determinato delle crescenti problematiche di surriscaldamento dell'ambiente interno. Molti degli edifici ad alta efficienza energeti-ca di nuova......'aria per rimuovere i carichi ambiente e, dall'altro, incrementa lo scambio termico sul corpo umano, poiché aumenta la velocità locale dell'aria sulla pelle, modificando quindi e le sensazioni termiche. Permette, inoltre, di abbinare la funzione di controllo dell'IAQ con quella del controllo termico. Una...

  18. Hearing Office Dispositions Per ALJ Per Day Rate Ranking Report

    Data.gov (United States)

    Social Security Administration — A ranking of ODAR hearing offices by the average number of hearings dispositions per ALJ per day. The average shown will be a combined average for all ALJs working...

  19. Soil carbon 4 per mille

    NARCIS (Netherlands)

    Mulder, V.L.

    2017-01-01

    The ‘4 per mille Soils for Food Security and Climate’ was launched at the COP21 with an aspiration to increase global soil organic matter stocks by 4 per 1000 (or 0.4 %) per year as a compensation for the global emissions of greenhouse gases by anthropogenic sources. This paper surveyed the soil

  20. Soil Carbon 4 per mille

    Science.gov (United States)

    Minasny, Budiman; van Wesemael, Bas

    2017-04-01

    The '4 per mille Soils for Food Security and Climate' was launched at the COP21 aiming to increase global soil organic matter stocks by 4 per mille (or 0.4 %) per year as a compensation for the global emissions of greenhouse gases by anthropogenic sources. This paper surveyed the soil organic carbon (SOC) stock estimates and sequestration potentials from 20 regions in the world (New Zealand, Chile, South Africa, Australia, Tanzania, Indonesia, Kenya, Nigeria, India, China Taiwan, South Korea, China Mainland, United States of America, France, Canada, Belgium, England & Wales, Ireland, Scotland, and Russia) and asked whether the 4 per mille initiative is feasible. This study highlights region specific efforts and scopes for soil carbon sequestration. Reported soil C sequestration rates generally show that under best management practices, 4 per mille or even higher sequestration rates can be accomplished. High C sequestration rates (up to 10 per mille) can be achieved for soils with low initial SOC stock (topsoil less than 30 t C ha-1), and at the first twenty years after implementation of best management practices. In addition, areas that have reached equilibrium but not at their saturation level will not be able to further increase their sequestration. We found that most studies on SOC sequestration globally only consider topsoil (up to 0.3 m depth), as it is considered to be most affected by management techniques. The 4 per mille initiative was based on a blanket calculation of the whole global soil profile C stock, however the potential to increase SOC is mostly on managed agricultural lands. If we consider 4 per mille on global topsoil of agricultural land, SOC sequestration is about 3.6 Gt C per year, which effectively offset 40% of global anthropogenic greenhouse gas emissions. As a strategy for climate change mitigation, soil carbon sequestration buys time over the next ten to twenty years while other effective sequestration and low carbon technologies become

  1. Humanistes per al segle XXI

    Directory of Open Access Journals (Sweden)

    Joan Campàs

    2004-04-01

    Full Text Available A partir d'unes consideracions crítiques respecte als qui, davant dels nous reptes i transformacions de la societat de la informació que afecten els àmbits de la cultura, del coneixement i de l'aprenentatge, només expliciten pors i temors i, d'altra banda, a partir d'una valoració positiva del Manifest de l'humanista del segle xxi, aquest article proposa una reflexió sobre tres aspectes que servirien per a reconfigurar un nou humanisme digital: el paradigma de la complexitat, la revolució digital i la mundialització, per a desembocar en una invitació a la praxi política compromesa per tal de no convertir l'humanista en una entelèquia cultural i un simple caprici ornamental del sistema.

  2. Aplicatiu per a Cafeteria Andana

    OpenAIRE

    Fortuny Navarro, Jordi

    2012-01-01

    La finalitat del projecte és la realització d'una aplicació per gestionar l'activitat d'una cafeteria. El projecte consta de dues parts ben diferenciades: - Una part interna o Intranet, en la que el propietari podrà portar un control del negoci i on podrà establir una interacció amb els clients, fet que ajudarà a millorar la gestió del negoci. - I una part externa o web pública, accessible per a tothom. Actualment la xarxa és un aparador a nivell mundial que permet als petits negocis donar-se...

  3. GDP per capita since 1820

    NARCIS (Netherlands)

    Bolt, Jutta; Timmer, Marcel; van Zanden, Jan Luiten|info:eu-repo/dai/nl/071115374

    2014-01-01

    Since 1820, the world economy experienced spectacular growth in output and income. This chapter builds upon the work by Angus Maddison and shows that the world’s average GDP per capita increased by a factor of 10 between 1820 and the 2010. Yet, this growth was spread very unevenly, resulting in a

  4. PER 2006 (1) Loretta - article

    African Journals Online (AJOL)

    Dr Tanya du Plessis

    the world.1 In 1999 approximately 250 000 hectares of farmland was planted with GM crops. This figure has increased by 100 000 hectare per year.2 South. Africa is ... 1 Biowatch http://www.biowatch.org.za/docs/booklets/gebk4.pdf 15 Jun. 2 Id. The ... subject to transboundary movement for direct use as food or feed, or for.

  5. Per Højholts monologer

    DEFF Research Database (Denmark)

    Nielsen, Klaus

    2010-01-01

    Per Højholt’s monologues: about Gitte, the paratext and the concept of the literary work in a book historic perspective To the field of literary studies book history and bibliography offer insights of immense value in particular with regards to the concept of the literary work. In this article I...... will present an example of how interpretation is affected when the literary work is viewed in a book historic and material perspective. The Danish postmodernist writer Per Højholt had his biggest commercial success with the work Gitte’s Monologues (1980-1984). The monologues enjoyed a wide listening audience...... on the genesis of the work. Most monologues had been commissioned by national radio and other institutions, an aspect that has great bearing on the interpretation of the work. The bibliographical distinction between abstract work and material document is crucial in a case like Gitte’s monologues. The article...

  6. Pensare per immagini: una strada per la coscienza

    Directory of Open Access Journals (Sweden)

    Ferdinando Testa

    2005-12-01

    Full Text Available Pensare per immagini è uno stile particolare di pensiero; l’acquisizione della meta e dell’obiettivo avviene non secondo un modello lineare e unicamente basato sulla legge di causa–effetto, ma attraverso percorsi, strade ed itinerari, privilegiando le connessioni analogiche che, al pari degli assi cartesiani, rappresentano i veri nodi, punti di incontro il cui fulcro è costituito dalla dimensione simbolica ed immaginale. In tale contesto il pensiero che nasce viene costruito gradualmente; non è già dato in maniera preconfezionata, non è nato ancora all’orizzonte, e segue il ritmo ciclico della spirale piuttosto che una retta all’infinito. È un pensiero, che sullo sfondo dell’immaginale collega gli eventi e i fenomeni rispettando il tempo dell’esperienza.

  7. PROGETTO DIDATTICO PER DETENUTI STRANIERI

    Directory of Open Access Journals (Sweden)

    Claudia Savino

    2014-07-01

    Full Text Available Questo lavoro vuol offrire spunti didattici per l’alfabetizzazione sociolinguistica dei detenuti stranieri, attraverso la sperimentazione integrata di alcune metodologie glottodidattiche. In particolare propone un laboratorio interdisciplinare nel quale le attività di italiano L2 si mescolano alle suggestioni dell’arte figurativa. Nella prima parte, l’articolo delinea le interazioni comunicative entro le strutture penitenziarie, con le implicazioni culturali che ne derivano. Accenna inoltre ai progetti pilota dell’Università per Stranieri di Siena in quest’ambito. Nella seconda parte, centrale e sperimentale, l’autrice descrive un progetto didattico in via di definizione, rivolto a detenuti stranieri e italiani: un percorso di educazione linguistica attraverso l’immagine, quale proposta formativa di comunicazione interculturale. Ne evidenzia gli aspetti glottodidattici, sociolinguistici e socioculturali, per illustrare come l’apprendimento/acquisizione della lingua seconda, in reclusione, sia facilitato da una didattica integrata e flessibile, dove l’arte e la L2 sono funzionali al processo di rieducazione del detenuto.  Educational projects for foreign prisoners   Claudia Savino  This paper offers ideas for teaching sociolinguistic literacy to foreign prisoners, through the integrated testing of some language teaching methodologies. In particular, it proposes an interdisciplinary laboratory where Italian L2 activities are mixed with figurative art. In the first part, the article outlines the communicative interactions within the prison facilities, with the cultural implications that derive from it. Mention is made of the pilot projects of the University for Foreigners in Siena in this area. In the second part, the author describes an educational project under development, aimed at Italian and foreign prisoners: language education through art for teaching intercultural communication. It highlights language teaching

  8. Modellistica numerica per problemi differenziali

    CERN Document Server

    Quarteroni, Alfio

    2016-01-01

    In questo testo si introducono i concetti di base per la modellistica numerica di problemi differenziali alle derivate parziali. Si considerano le classiche equazioni lineari ellittiche, paraboliche ed iperboliche, ma anche altre equazioni, quali quelle di diffusione e trasporto, di Navier-Stokes e le leggi di conservazione. Si forniscono inoltre numerosi esempi fisici che stanno alla base di tali equazioni. Quindi si analizzano metodi di risoluzione numerica basati su elementi finiti (continui e discontinui), differenze finite, volumi finiti, metodi spettrali (continui e discontinui), nonché strategie di approssimazione più avanzate basate sui metodi di decomposizione di domini, i metodi a basi ridotte o quelli di risoluzione di problemi di controllo ottimale. In particolare vengono discussi gli aspetti algoritmici e di implementazione al calcolatore e si forniscono diversi programmi di semplice utilizzo. Il testo non presuppone una approfondita conoscenza matematica delle equazioni alle derivate parziali:...

  9. Medicare Hospital Spending Per Patient - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — The "Medicare hospital spending per patient (Medicare Spending per Beneficiary)" measure shows whether Medicare spends more, less or about the same per Medicare...

  10. Medicare Hospital Spending Per Patient - Hospital

    Data.gov (United States)

    U.S. Department of Health & Human Services — The "Medicare hospital spending per patient (Medicare Spending per Beneficiary)" measure shows whether Medicare spends more, less or about the same per Medicare...

  11. Medicare Hospital Spending Per Patient - State

    Data.gov (United States)

    U.S. Department of Health & Human Services — The "Medicare hospital spending per patient (Medicare Spending per Beneficiary)" measure shows whether Medicare spends more, less or about the same per Medicare...

  12. SVILUPPO DI SOLUZIONI SOFTWARE PER LA SISMOLOGIA

    OpenAIRE

    Lanucara, Piero; Ruggiero, Vittorio; Zampini, Stefano; Ferraro, Luca

    2012-01-01

    Sviluppare soluzioni software per la sismologia è diventato, ormai, indispensabile per comprendere i complessi fenomeni che regolano il funzionamento del sistema Terra, come ad esempio: lo studio degli effetti di Sito che consentono di caratterizzare con estrema precisione l’impatto in superficie di un terremoto potenzialmente distruttivo; la derivazione di modelli per lo studio della deformazione cosismica prodotta da grandi terremoti; le simulazioni dirette per il calcolo dei campi di defor...

  13. ENEA presenta sistema ADS per trattamento scorie

    CERN Multimedia

    2002-01-01

    "Arriva il sistema Ads (Accelerator driven system) per il trattamento dei rifiuti radioattivi. Lo studio di fattibilita' per l' innovativa tecnologia, realizzato da un gruppo di lavoro congiunto Enea, Cea, Cern e Ansaldo, e' stato presentato oggi nel corso di un workshop presieduto dal premio Nobel per la fisica, Carlo Rubbia" (1/2 page).

  14. Medicare hospital spending per patient (Medicare Spending per Beneficiary) – Additional Decimal Places

    Data.gov (United States)

    U.S. Department of Health & Human Services — The "Medicare hospital spending per patient (Medicare Spending per Beneficiary)" measure shows whether Medicare spends more, less or about the same per Medicare...

  15. Servei web per al software Identax

    OpenAIRE

    Santander Garcia, Victor

    2013-01-01

    Aquest projecte consisteix en una nova versió per a plataformes mòbils del software existent per a escriptori anomenat IDENTAX . El programa permet realitzar la identificació taxonòmica dels bacteris en un dispositiu mòbil i d'aquesta manera facilitar la feina a la comunitat microbiòloga.

  16. Antiaris toxic aria (Moraceae - a new distribution record to the Eastern Ghats

    Directory of Open Access Journals (Sweden)

    K. Ravikumar

    2009-01-01

    Full Text Available Antiaris toxicaria (Pers. Lesch. (Moraceae - a paleotropical species has so far been reported only from the Western Ghats and Andaman islands in India. The present collections from Tamil Nadu and Andhra Pradesh form a new report to the entire Eastern Ghats. Provided here are the latest nomenclature, brief description and some notes on its distribution.

  17. ( Tephrosia vogelii ) leave extract exposed to freshwater Cichlid fish

    African Journals Online (AJOL)

    ... a degeneration of kidney tubules. Phytochemical analysis of the leaves extract indicated the presence of alkaloid, tannin, saponin, cardiac glycoside, rotenone, steroids, balsam, phenol and volatile oil. The result of this study calls for the need to discourage the use of toxic plants for catching fish in Nigeria water bodies.

  18. In vitro anthelmintic effects of crude aqueous extracts of Tephrosia ...

    African Journals Online (AJOL)

    The prevalence of anthelmintic resistance and the consumer demand for alternative farming systems that limit the use of chemical anthelmintics has made the search for alternative gastrointestinal nematode parasites control methods crucial. Traditional medicinal/herbal plants can offer an alternative to the reliance on ...

  19. Potential larvicidal effects of Tephrosia vogelii leaf extract on Culex ...

    African Journals Online (AJOL)

    human and avian malaria, human and animal filariases, rickettsial infections such as Borrelia anserina in fowl .... swimming away from the light were confirmed as dead. Abbots formula (Table 3). Abbots formula takes .... activity in the mosquito larvae need to be carried out. Acknowledgements. We would like to express our ...

  20. Modeling Per Capita State Health Expenditure Variat...

    Data.gov (United States)

    U.S. Department of Health & Human Services — Modeling Per Capita State Health Expenditure Variation State-Level Characteristics Matter, published in Volume 3, Issue 4, of the Medicare and Medicaid Research...

  1. Deregulated expression of the Per1 and Per2 in human gliomas.

    Science.gov (United States)

    Xia, He-chun; Niu, Zhan-feng; Ma, Hui; Cao, Shuan-zhu; Hao, Shao-cai; Liu, Zhong-tao; Wang, Fan

    2010-05-01

    Growing evidence shows that the deregulation of the circadian clock plays an important role in the development of malignant tumors, including gliomas. However, the molecular mechanisms of genes controlling circadian rhythm in glioma cells have not been explored. Using reverse transcription polymerase chain reaction and immunohistochemistry techniques, we examined the expression of two important clock genes, Per1 and Per2, in 33 gliomas. In this study, out of 33 gliomas, 28 were Per1-positive, and 23 were Per2-positive. The expression levels of Per1 and Per2 in glioma cells were significantly different from the surrounding non-glioma cells (P0.05). While there was no difference in the intensity of immunoactivity for Per2 between high-grade gliomas and low-grade gliomas (r=-0.330, P=0.061), the expression level of Per1 in high-grade gliomas was significantly lower than that in low-grade gliomas(r=-0.433, P=0.012). In this study, we found that the expression of Per1 and Per2 in glioma cells was much lower than in the surrounding non-glioma cells. Therefore, we suggest that disturbances in Per1 and Per2 expression may result in the disruption of the control of normal circadian rhythm, thus benefiting the survival of glioma cells. Differential expression of circadian clock genes in glioma and non-glioma cells may provide a molecular basis for the chemotherapy of gliomas.

  2. Nitrate and (per)chlorate reduction pathways in (per)chlorate-reducing bacteria

    NARCIS (Netherlands)

    Oosterkamp, M.J.; Mehboob, F.; Schraa, G.; Plugge, C.M.; Stams, A.J.M.

    2011-01-01

    The reduction of (per)chlorate and nitrate in (per)chlorate-reducing bacteria shows similarities and differences. (Per)chlorate reductase and nitrate reductase both belong to the type II DMSO family of enzymes and have a common bis(molybdopterin guanine dinucleotide)molybdenum cofactor. There are

  3. Per-Pixel Lighting Data Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Inanici, Mehlika

    2005-08-01

    This report presents a framework for per-pixel analysis of the qualitative and quantitative aspects of luminous environments. Recognizing the need for better lighting analysis capabilities and appreciating the new measurement abilities developed within the LBNL Lighting Measurement and Simulation Toolbox, ''Per-pixel Lighting Data Analysis'' project demonstrates several techniques for analyzing luminance distribution patterns, luminance ratios, adaptation luminance and glare assessment. The techniques are the syntheses of the current practices in lighting design and the unique practices that can be done with per-pixel data availability. Demonstrated analysis techniques are applicable to both computer-generated and digitally captured images (physically-based renderings and High Dynamic Range photographs).

  4. Preface to Per Linguam 27(1

    Directory of Open Access Journals (Sweden)

    Christa van der Walt

    2011-09-01

    Full Text Available This first number of Per Linguam in 2011 sees an extended Editorial Board and we would like to welcome the following esteemed scholars: Prof Colin Baker from the University of Wales (Bangor, a specialist in bilingual education;Prof Herman Batibo from the University of Botswana, a specialist on African languages, language planning and policy issues in Africa; and Prof Petra Engelbrecht from the University of Canterbury, an educational psychologist. We hope that they will be as pleased to be associated with Per Linguam as we are to have them on board! We also say farewell to Prof Bonny Norton whose commitments prevent her from serving on the Board.  Her presence on the Board has lent stature to Per Linguam and she will be missed. We wish her all the best for the future and hope that we can convince her to return at some point in the future.

  5. Identitat corporativa per a un club esportiu

    OpenAIRE

    Zarzuela Puerta, Carlos

    2016-01-01

    Creació d'una identitat corporativa gràfica per a un club d'atletisme a partir d'una base. A partir del color principal, nom i logo de l'equip, es creen unes normes per unificar tots els continguts gràfics del club i crear-ne de nous sota aquests criteris. Per poder establir unes normes gràfiques, es crea un briefing amb la informació del club i s'estableix un manual d'identitat gràfica que actua com a document regulador de la línia gràfica de club. Es redissenya la pàgina web sota les normes...

  6. Women in Physics in Perú

    Science.gov (United States)

    Loayza, María Luisa Cerón; Vásquez, Yezeña Huaypar; Cabrejos, Jorge Aurelio Bravo

    2009-04-01

    The numbers of women receiving undergraduate and master's degrees in physics from San Marcos National University and undergraduate physics degrees from San Luis Gonzaga National University in Perú are reported. The number of undergraduate degrees in physics has increased for women in San Marcos University, but not for women earning master's degrees. Why don't women complete their post-degree studies? Economics and gender stereotypes are factors that women in Perú have to fight each day. Perú does not have a good scholar program in science, so few students are interested in beginning their university careers in science. Improvements in science education are needed for our country to reach its potential.

  7. Per mantenere una cultura musicale dobbiamo insegnarla

    Directory of Open Access Journals (Sweden)

    Philip Gossett

    2014-05-01

    Full Text Available Come musicologi, abbiamo il dovere di fare di più per coniugare i nostri interessi con quelli degli studiosi impegnati in altri campi, fra cui la storia e la storia dell’arte. Il mio contributo al simposio intende delineare alcuni dei problemi che dobbiamo affrontare oggi nel contesto scolastico, insistendo sull’idea che noi, in quanto studiosi, possiamo fare molto per eradicare questi problemi. Occorre capire che la nostra disciplina va considerata parte integrante del bagaglio culturale che ogni studente deve possedere.

  8. Does immigration boost per capita income?

    DEFF Research Database (Denmark)

    Felbermayr, Gabriel; Hiller, Sanne; Sala, Davide

    2010-01-01

    Using a cross-section of countries, we adapt Frankel and Romer's (1999) IV strategy to international labor mobility. Controlling for institutional quality, trade, and financial openness, we establish a robust and non-negative causal effect of immigration on real per capita income.......Using a cross-section of countries, we adapt Frankel and Romer's (1999) IV strategy to international labor mobility. Controlling for institutional quality, trade, and financial openness, we establish a robust and non-negative causal effect of immigration on real per capita income....

  9. Does Immigration Boost Per Capita Income?

    DEFF Research Database (Denmark)

    Felbermayr, Gabriel J.; Hiller, Sanne; Sala, Davide

    Using a cross-section of countries, we adapt Frankel and Romer's (1999) IV strategy to international labor mobility. Controlling for institutional quality, trade, and ?nancial openness, we establish a robust and non-negative causal e?ect of immigration on real per-capita income.......Using a cross-section of countries, we adapt Frankel and Romer's (1999) IV strategy to international labor mobility. Controlling for institutional quality, trade, and ?nancial openness, we establish a robust and non-negative causal e?ect of immigration on real per-capita income....

  10. Playware e robotica modulare per il gioco

    Directory of Open Access Journals (Sweden)

    Henrik H. Lund

    2009-01-01

    Full Text Available In questo contributo presentiamo e usiamo il concetto di building block robotico per la creazione di playware. Il concetto tecnologico di building block programmabili e dotati di input e output (ivi inclusa la comunicazione e dell'intelligenza artificiale embodied, che enfatizza la relazione fra morfologia e controllo.Per dare un esempio concreto del concetto di building block robotico, proponiamo le mattonelle che abbiamo creato, come elementi che compongono un nuovo tipo di campo giochi sul quale i bambini possono sperimentare un feedback immediato ai loro movimenti.

  11. Gestor de tiquets per a drets ARCO

    OpenAIRE

    Caballero Lemos, Patricia

    2013-01-01

    L'objectiu principal d'aquest projecte és estudiar diverses eines de ticketing i analitzar les seves característiques per poder escollir amb criteri aquella que resulti més convenient i sobre la qual realitzar les modificacions necessàries per adaptar-la a l'àmbit dels drets ARCO. El objetivo principal de este proyecto es estudiar diversas herramientas de ticketing y analizar sus características para poder elegir con criterio aquella que resulte más conveniente y sobre la que realizar las...

  12. Per uno studio sulla procedura delle concordanze

    Directory of Open Access Journals (Sweden)

    Luca Andrea Di Martino

    2012-12-01

    Full Text Available La procedura delle concordanze individua una tecnica interpretativa che solo in apparenza ritrova la propria ragione nello strutturalismo più sorvegliato: prima ancora di essere un metodo di studio, è di fatto una possibilità del testo, dal punto di vista del lettore, del critico e dell’autore. Qui si guarda alle concordanze anzitutto attraverso l’esperienza di tre filologi del secolo scorso (Barbi, Contini e Avalle, per proporne infine un esame per dir così tecnico, richiamando una categoria in particolare riproposta da Franco Brioschi (l’esemplificazione.

  13. Perú Centro de Culturas

    OpenAIRE

    Beltrán-Neira, Roberto J.; Profesor emérito, Profesor extraordinario investigador. Facultad de Estomatología. Universidad Peruana Cayetano Heredia. Lima,

    2014-01-01

    Cuando se examina el panorama cultural de América Precolombina, tres son los principales centros de civilización localizados en lo que actualmente son México, Guatemala y Perú.En Sudamérica, el desarrollo cultural estuvo concentrado en lo que hoy es el Perú, lo que lleva a preguntarnos cuáles fueron las condiciones que favorecieron el desarrollo de culturas de tan alto nivel como las de Chavín, Paracas y Huari, por ejemplo.La costa, árida en su mayor parte, con estrechos valles de aguas torre...

  14. Computationally efficient prediction of area per lipid

    DEFF Research Database (Denmark)

    Chaban, Vitaly V.

    2014-01-01

    Area per lipid (APL) is an important property of biological and artificial membranes. Newly constructed bilayers are characterized by their APL and newly elaborated force fields must reproduce APL. Computer simulations of APL are very expensive due to slow conformational dynamics. The simulated d...

  15. Vaccinatietoestand Nederland per 1 januari 2004

    NARCIS (Netherlands)

    Abbink F; Oomen PJ; Zwakhals SLN; de Melker HE; Ambler-Huiskes A; CIE

    2005-01-01

    In dit rapport treft u de cijfers aan van de vaccinatietoestand in Nederland per 1 januari 2004 voor zuigelingen, kleuters (4-jarigen) en schoolkinderen (9-jarigen) van de cohorten 2001, 1998 en 1993.De vaccinatiegraad in Nederland is al jaren zeer goed te noemen. Het afgelopen verslagjaar is de

  16. UTILITY OF THE TEN PER CENT RULE

    African Journals Online (AJOL)

    2001-11-01

    Nov 1, 2001 ... Objective: To measure asymmetry in grip strength between hands in left, right and mixed handers and to test utility of the ten per cent rule. Design: A cross sectional study. Setting: Queen Elizabeth Central Hospital, Blantyre, Malawi. Subjects: One hundred and seventy six healthy volunteers (102 males and ...

  17. Ligeti: Ricercare per organo / M. K.

    Index Scriptorium Estoniae

    M. K.

    1991-01-01

    Uuest heliplaadist "Ligeti: Ricercare per organo, Vivier, Les Communiantes, Cavana, Jodl; Scelsi: In nomine Lucis; Lennot: Livre d'Orgue-extrait; Richer: Orgue 88; Pärt: Pari intervallo, Pierre Bousseau (Orgel)" (AD:1990). Adda/TIS CD 581 240 (WD:59'45") DDD

  18. CYNODON DACTYLON (L.) PERS., AND ITS IMPLICATIONS

    African Journals Online (AJOL)

    2 Department of Biochemistry and Biological Sciences. Wye College, Ashford, UK. ABSTRACT: Leaves and branches of bermuda grass, Gynodon dactylon (L.) Pers., were exposed to various concentrations of N aCl and KC] salt solutions and were examined using light microscopy, electron microscopy and atomic.

  19. PER PhDs & Bachelor's Degrees

    Science.gov (United States)

    White, Susan C.

    2017-01-01

    Recently, the editor remarked to me that physics departments that offered a PhD with a specialization in Physics Education Research (PER) seemed to graduate more bachelor's degree recipients than those physics PhD departments that did not have the specialization. I was not convinced. That led to quite a bit of discussion between us. He compiled a…

  20. Characterization of (per)chlorate-reducing bacteria

    NARCIS (Netherlands)

    Wolterink, A.F.W.M.

    2004-01-01

    Some bacteria can use (per)chlorateas terminal electron acceptor for growth. These bacteria convert perchlorate via chlorate and chlorite into chloride and molecular oxygen. Oxygen formation in microbial respiration is unique. In this study two chlorate-reducing strains

  1. Annapolis achieves 99 per cent availability

    Energy Technology Data Exchange (ETDEWEB)

    DeLory, R.P.

    1986-07-01

    The Annapolis tidal power plant which officially came on line in 1984 is described. In its first year it achieved 99 per cent availability. It is the first tidal power plant in North America and the first plant in the world to employ a large diameter Straflo turbine.

  2. Un test per la faringits aguda

    OpenAIRE

    Madurell, Jordi

    2013-01-01

    La faringitis aguda és una de les raons més freqüents de consulta del metge d'atenció primària i en la major part dels casos es prescriu un antibiòtic. Ara bé, segons l'evidència científica només han de ser tractats amb antibiòtics aquells episodis de faringitis causats per un bacteri determinat, l'estreptococ β-hemolític del grup A (EBHGA). Segons sembla, només un 10-30% dels episodis aguts en nens i 10-15% dels casos en adults són causats per EBHGA. Aquesta tesi, presentada al Departament d...

  3. CALiPER Retail Lamps Study 3

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2014-02-01

    This is a special CALiPER report on LED lamps available through the retail marketplace and targeted toward general consumers. It follows similar reports published in 2011 and 2012 (products purchased in 2010 and 2011), and is intended as a continuation that identifies long-term trends. For this report, products were selected to investigate specific hypotheses, rather than represent a sample of the increasingly large retail LED market.

  4. Making It Personal: Per Capita Carbon Allowances

    DEFF Research Database (Denmark)

    Fawcett, Tina; Hvelplund, Frede; Meyer, Niels I

    2009-01-01

    The Chapter highligts the importance of introducing new, efficient schemes for mitigation of global warming. One such scheme is Personal Carbon Allowances (PCA), whereby individuals are allotted a tradable ration of CO2 emission per year.This chapter reviews the fundamentals of PCA and analyzes its...... merits and problems. The United Kingdom and Denmark have been chosen as case studies because the energy situation and the institutional setup are quite different between the two countries....

  5. LA LINGUA PER STUDIARE: UNA RASSEGNA BIBLIOGRAFICA

    Directory of Open Access Journals (Sweden)

    Marina Tassara

    2011-02-01

    Full Text Available I libri di testo adottati nelle scuole contengono parole sconosciute e costruzioni sintattiche e testuali complesse che rappresentano dei veri e propri “muri linguistici” per gli alunni stranieri che non possiedono una buona conoscenza della lingua italiana. Ciò facilmente determina un divario di competenze tra l’apprendente straniero e i suoi compagni e ritardi scolastici molto spesso incolmabili con conseguente perdita di motivazione e di autostima, senso di frustrazione e isolamento che a volte sfocia in un disagio psico-sociale. Tra gli strumenti adottati dalla scuola italiana per far fronte a questo problema vi sono i testi disciplinari ad alta comprensibilità che, pur mantenendo la maggior parte delle informazioni, le veicolano in una forma più semplice dal punto di vista linguistico. L’articolo fornisce una bibliografia di manuali ad alta comprensibilità il più possibile aggiornata suddivisa per ordine e grado di scuola e per materia scolastica, con l’intento di fornire agli insegnanti un aiuto nella scelta e nel reperimento dei testi.     Language for study:  a bibliography   Textbooks used in schools contain unknown words and complex sentence constructions that create real “linguistic barriers” for foreign students who do not know Italian well.  This creates an abyss between the competence of the foreign learner and his or her classmates and unsuccessful school performance which is often not made up for and leads to a loss of self-esteem, frustration, isolation, and ultimately to psycho-social malaise.  Among the tools utilized in the Italian school system to address this problem are highly comprehensible textbooks which, while containing most of the information, express the content in simpler language.  This article offers an up-dated bibliography of textbooks which are easily understandable, divided according to order and grade of school, for teachers to use in choosing the textbooks for their classes.

  6. Dodici comandamenti per l’accesso aperto

    Directory of Open Access Journals (Sweden)

    Maria Chiara Pievatolo

    2012-02-01

    Full Text Available Come può comportarsi un ricercatore che desidera diffondere l’accesso aperto non solo a parole, ma anche nei fatti? Avevo provato a rispondere, limitatamente all’arte della citazione. Mi hanno allora chiesto una guida che abbracciasse tutta l’attività di ricerca. Danah Boyd ha già prodotto qualcosa di simile: ecco un adattamento del suo lavoro per  l’uso degli [...

  7. Una nuova piattaforma per i Dati Aperti

    Directory of Open Access Journals (Sweden)

    Ernesto Lastres

    2013-02-01

    Full Text Available In un panorama di continua evoluzione ed interesse da parte della opinione pubblica sul tema dei “dati open” moltienti della pubblica amministrazione e di governo stanno svolgendo azioni specifiche per la concretizzazione di queste iniziative in ottica di open government. Tuttavia, sono in pochi quelli che nel settore privato hanno intrapreso delle iniziative importanti in tale direzione. In questo articolo presentiamo una iniziativa indipendente per una nuova piattaforma software dedicata ai dati open su internet che, se confermasse i propri scopi, costituirebbe un punto di partenza a livello nazionale per l’accesso a questi dati. In a very evolving context and in a particular moment of public interest in theme of open data, many public organizations and government institutions are carrying out specific actions for the realization of initiatives in order to promote the open government ideas. However, very few private organizations have launched initiatives in this direction. In this paper we present an independent initiative for a new software platform for opendata on the internet that aims to be a starting point at the national level for the access to these kind of data.

  8. CALiPER Retail Lamps Study 3

    Energy Technology Data Exchange (ETDEWEB)

    Royer, Michael P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Beeson, Tracy A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-02-01

    The CALiPER program first began investigating LED lamps sold at retail stores in 2010, purchasing 33 products from eight retailers and covering six product categories. The findings revealed a fragmented marketplace, with large disparities in performance of different products, accuracy of manufacturer claims, and offerings from different retail outlets. Although there were some good products, looking back many would not be considered viable competitors to other available options, with too little lumen output, not high enough efficacy, or poor color quality. CALiPER took another look in late 2011purchasing 38 products of five different types from nine retailers and the improvement was marked. Performance was up; retailer claims were more accurate; and the price per lumen and price per unit efficacy were down, although the price per product had not changed much. Nonetheless, there was still plenty of room for improvement, with the performance of LED lamps not yet reaching that of well-established classes of conventional lamps (e.g., 75 W incandescent A19 lamps). Since the second retail lamp study was published in early 2012, there has been substantial progress in all aspects of LED lamps available from retailers. To document this progress, CALiPER again purchased a sample of lamps from retail stores 46 products in total, focusing on A19, PAR30, and MR16 lamps but instead of a random sample, sought to select products to answer specific hypotheses about performance. These hypotheses focused on expanding ranges of LED equivalency, the accuracy of lifetime claims, efficacy and price trends, as well as changes to product designs. Among other results, key findings include: There are now very good LED options to compete with 60 W, 75 W, and 100 W incandescent A19 lamps, and 75 W halogen PAR30 lamps. MR16 lamps have shown less progress, but there are now acceptable alternatives to 35 W, 12 V halogen MR16 lamps and 50 W, 120 V halogen MR16 lamps for some applications. Other

  9. Interstellar Abundances Toward X Per, Revisited

    Science.gov (United States)

    Valencic, Lynne A.; Smith, Randall K.

    2014-01-01

    The nearby X-ray binary X Per (HD 24534) provides a useful beacon with which to measure elemental abundances in the local ISM. We examine absorption features of 0, Mg, and Si along this line of sight using spectra from the Chandra Observatory's LETG/ ACIS-S and XMM-Newton's RGS instruments. In general, we find that the abundances and their ratios are similar to those of young F and G stars and the most recent solar values. We compare our results with abundances required by dust grain models.

  10. La prensa chicha en Perú

    Directory of Open Access Journals (Sweden)

    Mónica S Cappellini

    2015-01-01

    Full Text Available Analiza las características y comportamiento del periodismo chicha en Perú, una forma de sensacionalismo, de preferencias populares que se desarrolla como un moderno ejemplo mediático de entretenimiento. La cultura chicha representa un grupo de costumbres de una subcultura limeña, tomó este nombre por su relación con lo indígena. Los diarios chicha son leídos preferentemente por los niveles socieconómicos bajos y muy bajos éstos no tienen impacto en la opinión pública.

  11. Blockchain per l'educació

    OpenAIRE

    Arcas Sanz, Joan Manel

    2017-01-01

    La tecnologia Blockchain o de cadena de blocs va sorgir com a suport de la xarxa de monedes virtuals Bitcoin, però amb la recent aparició dels Smart Contracts existeix la possibilitat de crear infinitud d'aplicacions que funcionin de manera distribuïda i sense la necessitat d'entitats intermediàries. En aquest article es presenta una introducció a la tecnologia Blockchain, des dels seus inicis amb Bitcoin fins a l'actualitat amb la utilització dels Smart Contracts. Posteriorment es comparen a...

  12. Obituary: Per E. Maltby, 1933-2006

    Science.gov (United States)

    Kjeldseth-Moe, Olav

    2007-12-01

    Professor Per Maltby, prominent Norwegian Solar Physicist at the Institute of Theoretical Astrophysics, University of Oslo, Norway, died on 24 May 2006. Lung cancer was diagnosed in February, but he was expected to improve. Until the end of March he came to his office every day, got recent papers off the web, and followed his field closely as he had always done. Per Maltby was born in Oslo, Norway, on 3 November 1933. He started his studies at the University of Oslo in 1952 and took his candidate degree in 1957. Between 1955 and 1958 he was a research assistant at the Institute of Theoretical Astrophysics in Oslo. In 1960 Maltby became an assistant professor (amanuensis) at the University of Bergen and from January 1963 he held a corresponding position at the University of Oslo. He became an associate professor in 1967, and from 1983 until he retired in 2003 he was a full Professor at the Institute of Theoretical Astrophysics, University of Oslo. Per Maltby is survived by his wife Elisabet (née Ruud), whom he married in 1956. They had two children. The daughter, Bente, is a medical doctor and gynecologist serving as a section head at the district hospital in Kristiansand in southern Norway. Their son, Lars, holds a doctoral degree in engineering, specializing in the properties of powders. He is currently managing director in the Norwegian division of the French multinational company Saint Gobain. As a father Per Maltby expressed pride in his children and was pleased with their progress in life. He also enjoyed his five grandchildren. As a scientist, Per Maltby was versatile and productive. In the early 1960s he visited the California Institute of Technology where he did pioneering studies of the distribution and time variation of the radio emission from active galaxies, using the Owens Valley Radio Observatory. His work with Alan Moffet contributed to revealing the secrets of these remote objects. Their results drew attention and were indeed mentioned in the pages

  13. Characterizing Energy per Job in Cloud Applications

    Directory of Open Access Journals (Sweden)

    Thi Thao Nguyen Ho

    2016-12-01

    Full Text Available Energy efficiency is a major research focus in sustainable development and is becoming even more critical in information technology (IT with the introduction of new technologies, such as cloud computing and big data, that attract more business users and generate more data to be processed. While many proposals have been presented to optimize power consumption at a system level, the increasing heterogeneity of current workloads requires a finer analysis in the application level to enable adaptive behaviors and in order to reduce the global energy usage. In this work, we focus on batch applications running on virtual machines in the context of data centers. We analyze the application characteristics, model their energy consumption and quantify the energy per job. The analysis focuses on evaluating the efficiency of applications in terms of performance and energy consumed per job, in particular when shared resources are used and the hosts on which the virtual machines are running are heterogeneous in terms of energy profiles, with the aim of identifying the best combinations in the use of resources.

  14. Una imatge val per mil paraules

    Directory of Open Access Journals (Sweden)

    Jaume Cabré

    1999-11-01

    Full Text Available Una vegada hi havia un videoclub ple de pel·lícules i a l'entrada hi havia un rètol lluminós molt bonic que deia el lema d'aquesta casa, que és una imatge val per mil paraules. I vet aquí un dia que la clientela ja se n'havia anat, però encara no havien tancat els llums, van entrar al videoclub dues rates, l'Amàlia i l'Amèlia. I van dir: "Què fem avui?" Aleshores l'Amèlia se'n va anar de seguida cap al racó de la sèrie B i va agafar una pel·lícula poc coneguda, mentre que l'Amàlia va agafar Mort a Venècia. Llavors la va començar a rosegar i l'Amèlia li va dir: "Què, què te'n sembla?", i l'Amàlia li va contestar: "Mmm... Em va agradar més la novel·la."

  15. Ipotesi per l'attore del futuro

    Directory of Open Access Journals (Sweden)

    Marco Galignano

    2012-01-01

    Full Text Available Abstract – IT Il teatro è in subbuglio perché il mondo tutto è in subbuglio. Ciclicità probabilmente, nel presente difficile. Crisi. Storiografia, società, umanità, nuove forme di teatro, scontro/incontro di etnologie, scienza nuova in fermento (biologia, fisica, chimica, tecnologia, astronomia, nuovi orizzonti di conoscenza, attori che si cercano, contaminazioni artistiche di genere, pedagogie da rifare. Caos. Tradizioni sconvolte e nuove necessità. Economia allo spasmo. Eppure esiste una strada positiva, attuabile nella sfera del privato, del personale. La salute, intesa come scopo di esistenza; la poesia, in connessione con il mistero ontologico; l’arte, specchio e riflesso della vita, potrebbero essere i capisaldi di una nuova integrazione, psicofisica, volta alla riscoperta del naturale, del benessere umano. Si cerca qui di proporre delle strade che vadano in questa direzione. Ipotesi di vita, per il teatro, per l’attore. Per l’essere umano nel nuovo millennio. Ipotesi su come possano fondersi le conoscenze più avanzate sulla salute organica dell’essere umano, recuperando la sapienza antica a volte incomprensibilmente dimenticata; la parte più aulica, nel senso di elevata, raffinata e funzionale dell’arte dello spettacolo. Abstract – EN Theatre is in a turmoil, because the whole world is in a turmoil. Cyclical pattern, perhaps, in a difficult present time. Crisis. Historiography, society, humankind, new ways of making theatre, ethnological encounter and clashing, new science in a state of ferment (biology, physics, chemistry, technology, astronomy, new horizons of knowledge, actors in search of each other, artistic gender contamination, science of education to be built anew. Chaos. Upset tradition and new needs. Suffering economy. Nevertheless, a positive way does exist and it’s workable in your own personal environment. Health meant as a goal of existence, poetry connected with ontological mystery and art as a

  16. Macchine per giuoco nella proposta di Leopardi

    Directory of Open Access Journals (Sweden)

    Laura Neri

    2017-06-01

    Full Text Available Un’operetta morale di Leopardi, la Proposta di premi fatta dall’Accademia dei Sillografi, adotta il linguaggio tecnico di un bando di concorso per proporre tre premi agli inventori di tre macchine umane perfette: l’amicizia, la magnanimità, la fedeltà coniugale sono gli obiettivi delle invenzioni scientifiche. Il tono serio cela in realtà la  polemica contro l’antropocentrismo e soprattutto contro l’ottimismo del suo tempo.  One of Leopardi’s Operette morali, Proposta di premi fatta dall’Accademia dei Sillografi, adopts the gergon of a competition notice to propose three prizes to the inventors of three perfect human machines: friendship, magnanimity, conjugal fidelity are the aims of scientific inventions. The serious tone really conceals the controversy against anthropocentrism and above all against the optimism of its time.

  17. Bianco su nero. Una storia per strada

    Directory of Open Access Journals (Sweden)

    Maria Elena Buslacchi

    2013-03-01

    Full Text Available “Per raccontare questa storia bisogna partire da Odessa” – e girare il mondo, con l’immaginazione, ma anche con i piedi. A maggio 2012, a Genova, è comparsa una scritta bianca che attraversa il centro storico. Questo è il prologo. Anche se ormai sbiadita, ancora oggi è impossibile non notarla: parte proprio di fronte a Palazzo Ducale, si inoltra nei vicoli, da quelli più frequentati a quelli meno noti e battuti, termina, o meglio, s’interrompe sulla riva del mare. Dalla banchina sul porto cade in acqua. E si dice continui in Israele, dove prosegue la storia che narra, ma nessuno si è ancora preso la premura di verificare. Forse perché non conta davvero come finisca la storia: quel che conta è seguirla.

  18. Marjane Satrapi. Persépolis

    Directory of Open Access Journals (Sweden)

    Charbanou Jochum-Maghsoudnia

    2009-05-01

    Full Text Available Dans les quatre volumes de sa bande dessinée Persépolis Marjane Satrapi décrit et illustre en noir et blanc son autobiographie. Elle y superpose de manière vertigineuse et transparente les événements et les faits marquants de l’Iran contemporain qu’elle entremêle avec les vies au quotidien sous le régime des mollahs. Le récit de sa vie d’adolescente exilée fait appel à des questions universelles comme celles de l’intégration, de l’adaptation à d’autres cultures et de l’identité.Née en Iran en...

  19. Effectiveness of 3 per cent boric acid in 70 per cent alcohol versus 1 per cent clotrimazole solution in otomycosis patients: a randomised, controlled trial.

    Science.gov (United States)

    Romsaithong, S; Tomanakan, K; Tangsawad, W; Thanaviratananich, S

    2016-09-01

    To compare the clinical effectiveness and adverse events for 3 per cent boric acid in 70 per cent alcohol versus 1 per cent clotrimazole solution in the treatment of otomycosis. A total of 120 otomycosis patients were randomly assigned to receive either 1 per cent clotrimazole solution (intervention group) or 3 per cent boric acid in 70 per cent alcohol (control group) at the Khon Kaen Hospital ENT out-patient department. Treatment effectiveness was determined based on the otomicroscopic absence of fungus one week after therapy, following a single application of treatment. After 1 week of treatment, there were data for 109 participants, 54 in the clotrimazole group and 55 in the boric acid group. The absolute difference in cure rates between 1 per cent clotrimazole solution and 3 per cent boric acid in 70 per cent alcohol was 17.9 per cent (95 per cent confidence interval, 2.3 to 33.5; p = 0.028) and the number needed to treat was 6 (95 per cent confidence interval, 3.0 to 43.4). Adverse events for the two agents were comparable. One per cent clotrimazole solution is more effective than 3 per cent boric acid in 70 per cent alcohol for otomycosis treatment.

  20. Las elecciones presidenciales en Perú

    Directory of Open Access Journals (Sweden)

    Fernando TUESTA SOLDEVILLA

    2009-11-01

    Full Text Available RESUMEN: Este artículo presenta un comentario de los resultados de las elecciones presidenciales de 1995 en Perú. Después de realizar un repaso de los datos resultantes de los comicios, el autor analiza algunas de las razones que explican el amplio triunfo del presidente Fujimori, quien diluyó su imagen autoritaria en los éxitos obtenidos en materia de estabilización económica y pacificación social. Seguidamente se repasan los procesos que enmarcaron esta evolución política: el declive de los partidos políticos, la debilidad de las instituciones, la evolución de la prefencia de voto y el aumento de la participación de la mujer en el ámbito político.ABSTRACT: This article presents a comment about the results of the last presidential elections in Peru. Following an overview of the electoral data, the author analizes some of the reasons of the presidente Fujimori's victory, who diluted his autoritharian imagen behind his successful policy on subjects such as economic stabilization and terrorism. Next, he makes a reflection on the various processes which framed such a political evolution: the decline of the political parties, the weakness of the different political institutions, the changes on the electoral preferences and the increase of women's political participation.

  1. Quali interlocutori per ’inchiesta sociale?

    Directory of Open Access Journals (Sweden)

    Piano b

    2009-06-01

    Full Text Available La chiusura delle fabbriche, la scomparsa della classe operaia, la riconversione dei capannoni dismessi. La città post-industriale, dei servizi, dei centri commerciali. L’immigrazione, la città multietnica, la questione della sicurezza, l’insicurezza percepita dai cittadini italiani nei propri quartieri. Il lavoro precario, il consumismo, la speculazione edilizia, l’inquinamento, la fine delle “comunità”, la parcellizzazione dei rapporti sociali. Parole che da anni leggiamo e ascoltiamo e che ci sembra descrivano in modo appropriato i fenomeni e le trasformazioni in atto nelle città italiane. Ma anche parole di “senso comune”, che diamo per scontate. Descrizioni dei mondi in cui viviamo che è difficile mettere in discussione, che solitamente vengono evocate piuttosto che argomentate. Parole che basta nominare perché tutti bene o male capiscano di cosa si sta parlando. Che ci mostrano in maniera inequivocabile la direzione nella quale sta andando la società in cui viviamo. E, aspetto non secondario, inibiscono l’azione politica collettiva e la nascita di progetti di segno diverso.

  2. Per- and Polyfluoroalkyl Substances (PFAS): Sampling ...

    Science.gov (United States)

    Per- and polyfluoroalkyl substances (PFAS) are a large group of manufactured compounds used in a variety of industries, such as aerospace, automotive, textiles, and electronics, and are used in some food packaging and firefighting materials. For example, they may be used to make products more resistant to stains, grease and water. In the environment, some PFAS break down very slowly, if at all, allowing bioaccumulation (concentration) to occur in humans and wildlife. Some have been found to be toxic to laboratory animals, producing reproductive, developmental, and systemic effects in laboratory tests. EPA's methods for analyzing PFAS in environmental media are in various stages of development. This technical brief summarizes the work being done to develop robust analytical methods for groundwater, surface water, wastewater, and solids, including soils, sediments, and biosolids. The U.S. Environmental Protection Agency’s (EPA) methods for analyzing PFAS in environmental media are in various stages of development. EPA is working to develop robust analytical methods for groundwater, surface water, wastewater, and solids, including soils, sediments, and biosolids.

  3. App per l’infanzia: linee guida per una progettazione efficace

    Directory of Open Access Journals (Sweden)

    Silvia Carbotti

    2015-04-01

    Full Text Available I bambini sono affascinati dai tablet e dai dispositivi mobili di ultima generazione. Allo stesso modo si trovano in una fase della vita in cui iniziano a formare preferenze e competenze così come ad esprimere le proprie emozioni e sensazioni attraverso la parola. Questo articolo descrive le strategie per la creazione di applicazioni (app per bambini che siano non solo divertenti ma anche efficaci per esperienze significative che li coinvolgano a livello cognitivo ed emotivo. Quando si disegnano app rivolte ai bambini occorre ricordare che i più piccoli non hanno ancora chiaro come dovrebbe funzionare una specifica tecnologia ma si stanno formando un’opinione a riguardo. Diventa dunque necessario considerare alcuni principi di interaction e visual design affinché l’esperienza vissuta con il tablet incontri bisogni e competenze.

  4. Studio di prototipo di calorimetro per neutroni per l'esperimento ALICE

    CERN Document Server

    Arnaldi, R; Cicalò, C; Cortese, P; De Falco, A; Dellacasa, G; De Marco, N; Gallio, M; Macciotta, P; Masoni, A; Musso, A; Oppedisano, C; Piccotti, A; Puddu, G; Scomparin, E; Siddi, S; Serci, E; Soave, C; Usai, G L; Vercellin, Ermanno

    1999-01-01

    ALICE e uno dei quattro esperimenti previsti ad LHC, al CERN, il cui scopo e lo studio delle osservabili che danno informazioni rilevanti sulla formazione del quark gluon plasma, che potrebbe essere prodotto in collisioni centrali Pb-Pb, di energia nel centro di massa di 5.5 A TeV.Il parametro di impatto di tali collisioni verra determinato grazie ad un insieme di calorimetri per protoni e neutroni che misureranno l'energia portata in avanti dai nucleoni non interagenti(spettatori).E' stato costruito un prototipo di calometro per neutroni, formato da piani di fibre di quarzo, posti a 45 gradi rispetto all'asse del fascio e inframmezzati da piani di materiale passivo denso(tungsteno). La luce Cerenkov prodotta nelle fibre dallo sciame sviluppato nel materiale passivo,viene raccolta da guide ottiche in aria.Verranno presentati i rilustati di un test previsto al CERN SPS per il luglio 1999.

  5. Desenvolupament d'un plugin per a Chrome per xifrar/desxifrar correus utilitzant Gmail

    OpenAIRE

    Martín Toral, Boris

    2016-01-01

    L'objecte del treball final de carrera és desenvolupar un plugin o extensió per a Chrome per a poder xifrar/desxifrar missatges utilitzant el correu web de Gmail. S'adjunta memòria, presentació virtual i codi font de l'extensió desenvolupada. The purpose of the final project work is to develop a plugin or extension for Chrome in order to encrypt/decrypt messages using the Gmail web mail. Attached report, presentation and virtual source extension developed. El objetivo del trabajo final ...

  6. Processi e temi per una smartculturalcity

    Directory of Open Access Journals (Sweden)

    Marco Gaiani

    2013-12-01

    Full Text Available ItIn questo contributo si assume il concetto di ‘Smart City’ come paradigma per sottolineare l’importanza che riveste l’Information Technology (IT di prima e seconda generazione ai fini del miglioramento del profilo competitivo di una città, soprattutto per ciò che riguarda il patrimonio culturale in essa contenuto. Si estende così il costrutto di William Mitchell dalla città al patrimonio culturale precisando, anche attraverso alcune esemplificazioni, come le Smart IT modifichino profondamente le modalità di trasmissione, acquisizione e produzione della conoscenza trasformando quest’ultima in un fattore di sviluppo economico, sociale e culturale. Non secondariamente esse contribuiscono alla soluzione di problemi tipici dei processi connessi al lifecycle dei beni culturali: la loro conservazione, fruizione, comunicazione e gestione, nonché quelli connessi alla grande quantità di dati e alla loro eterogeneità. Infine, i nuovi sistemi come l’Internet of Things o il fenomeno dello User Generated Content permettono di concepire i beni culturali come ‘smart cultural objects’ e la generazione di conoscenza da parte degli utenti. Tutto ciò, se da una parte amplifica le possibilità di interazione tra soggetti e oggetti della conoscenza, dall’altra ne modifica radicalmente le modalità. Questo deve sollecitare le Università, le Istituzioni culturali e le Imprese a collaborare, nel prossimo futuro, sugli usi possibili delle soluzioni tecnologiche prospettate, in vista dell’affermazione di una più consapevole e partecipata cultura della sostenibilità del nostro patrimonio culturale.EnThis contribution takes the concept of ' Smart City ' as a paradigm in order to underline the importance of first and second generation of Information Technology (IT for the purpose of improving the competitiveness of a city, especially for what concerns its Cultural Heritage (CH. We extends so the construct of William Mitchell from the city to

  7. INTERSTELLAR ABUNDANCES TOWARD X Per, REVISITED

    Energy Technology Data Exchange (ETDEWEB)

    Valencic, Lynne A. [Johns Hopkins University, Baltimore, MD 21218 (United States); Smith, Randall K. [Smithsonian Astrophysical Observatory, Cambridge, MA 02138 (United States)

    2013-06-10

    The nearby X-ray binary X Per (HD 24534) provides a useful beacon with which to examine dust grain types and measure elemental abundances in the local interstellar medium (ISM). The absorption features of O, Fe, Mg, and Si along this line of sight were measured using spectra from the Chandra X-Ray Observatory's LETG/ACIS-S and XMM-Newton's RGS instruments, and the Spex software package. The spectra were fit with dust analogs measured in the laboratory. The O, Mg, and Si abundances were compared to those from standard references, and the O abundance was compared to that along lines of sight toward other X-ray binaries. The results are as follows. First, it was found that a combination of MgSiO{sub 3} (enstatite) and Mg{sub 1.6}Fe{sub 0.4}SiO{sub 4} (olivine) provided the best fit to the O K edge, with N(MgSiO{sub 3})/N(Mg{sub 1.6}Fe{sub 0.4}SiO{sub 4}) = 3.4. Second, the Fe L edge could be fit with models that included metallic iron, but it was not well described by the laboratory spectra currently available. Third, the total abundances of O, Mg, and Si were in very good agreement with that of recently re-analyzed B stars, suggesting that they are good indicators of abundances in the local ISM, and the depletions were also in agreement with expected values for the diffuse ISM. Finally, the O abundances found from X-ray binary absorption spectra show a similar correlation with Galactocentric distances as seen in other objects.

  8. Per una lettura laica della teologia medievale

    Directory of Open Access Journals (Sweden)

    Dino Buzzetti

    2010-02-01

    Full Text Available È possibile operare una forma di epoché sui concetti di carattere teologico? Ed è possibile riflettere sulla loro importanza, prescindendo dalla loro portata religiosa? I concetti teologici riescono a dirci qualcosa, se si trascura il loro riferimento essenziale alla nostra relazione con un essere divino? La risposta a queste domande consente di comprendere che cosa significhi essere un studioso laico della filosofia medievale, mentre è impossibile discutere tale problema senza prendere in considerazione anche la teologia medievale. Tutto ciò dunque riguarda non solo la natura della teologia, ma anche l’idea stessa di laicità. Dunque una storiografia del pensiero medievale pienamente consapevole di se stessa deve studiare il discorso teologico e affrontare in profondità la portata teorica di questo problema. Si può concludere che per una lettura laica della teologia medievale è paradossalmente essenziale cogliere proprio il senso intimo del pensiero religioso e le forme storicamente determinate della sua effettiva concettualizzazione.  Is some form of epoché possible on theological concepts? In which way? Is it possible consider their importance leaving their religious scope aside? Can the theological concepts tell us something unless we consider their essential reference to our relationship with a divine being? The answer to these questions let us to understand what means to be a secular (laico scholar of medieval philosophy. It's impossible conversely to discuss this problem without dealing with medieval theology. And this concerns not only the nature of theology, but also and deeply the same idea of secularism (laicità. Therefore a fully aware historiography of medieval thought has to understand the theological speech and to encounter the depth of this theoretical question. So we can conclude that for a secular reading of the medieval theology is paradoxically essential to catch the intimate sense of religious thought and the

  9. 38 CFR 61.33 - Payment of per diem.

    Science.gov (United States)

    2010-07-01

    ...) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.33 Payment of per diem. (a) A capital grant... non-grant recipient for those homeless veterans— (1) Who VA referred to the grant recipient or non... per diem recipient for furnishing services to homeless veterans that the per diem recipient certifies...

  10. 38 CFR 61.30 - Per diem-general.

    Science.gov (United States)

    2010-07-01

    ... HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.30 Per diem-general. VA provides per diem funds to... of supportive housing or services after November 10, 1992 so they can assist homeless veterans by... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Per diem-general. 61.30...

  11. La correlazione di immagini per la generazione di modelli 3D per il patrimonio costruito

    Directory of Open Access Journals (Sweden)

    Filiberto Chiabrando

    2013-06-01

    Full Text Available I modelli dettagliati 3D derivati dalle tecniche di rilievo metrico digitale vengono impiegati con crescente sviluppo in moltissimi campi applicativi, dal rilievo del territorio e delle aree urbane, per i quali sono stati testati e messi a punto processi di elaborazione di dati satellitari o aerei, ai beni paesaggistici strettamente correlati al territorio fino alla sfera dei Beni Culturali. L’elevato dettaglio ottenibile delle superfici e la loro accuratezza li rende particolarmente stimati per un largo insieme di finalizzazioni. Questo contributo esamina in particolare i cosiddetti sensori passivi e i relativi sistemi di correlazione d’immagine, poiché l’efficacia dei modelli ottenibili, il basso costo e la ricchezza d’informazione offerta, rendono questi modelli di importanza strategica nei settori caratterizzati da scarse risorse come quello dei Beni Culturali. Dopo una breve rassegna dei metodi disponibili, è riportato un esame dell’applicazione degli algoritmi di base implementati in due diffusi software; a corredo alcune valutazioni circa le strategie di matching in riferimento alle geometrie di acquisizione, alle tipologie di materiali e finiture superficiali degli oggetti rilevati. Una sezione sperimentale finale descrive alcuni test ed una loro lettura critica per la comparazione di differenti soluzioni da riferire a diversi casi studio.

  12. PER-8, a Novel Extended-Spectrum β-Lactamase PER Variant, from an Acinetobacter baumannii Clinical Isolate in Nepal.

    Science.gov (United States)

    Tada, Tatsuya; Shrestha, Shovita; Shimada, Kayo; Ohara, Hiroshi; Sherchand, Jeevan B; Pokhrel, Bharat M; Kirikae, Teruo

    2017-03-01

    A novel PER-type extended-spectrum β-lactamase, PER-8, was identified in an Acinetobacter baumannii clinical isolate obtained in Nepal. The amino acid sequence of PER-8 has a substitution at position 39 (Gly to Glu) compared with that of PER-7. The kcat/Km ratio of PER-8 for aztreonam was lower than that of PER-7, while the kcat/Km ratio of PER-8 for imipenem was higher than that of PER-7. The genomic environment surrounding blaPER-8 was intI1 blaPSE-1qacEDI sulI ISCR1-blaPER-8gts sulI orfX on a 100-kb plasmid. Copyright © 2017 American Society for Microbiology.

  13. Perú-Chile: imágenes mutuas (Perú-Chile: mutual images

    Directory of Open Access Journals (Sweden)

    Álvaro González Riesle

    2014-06-01

    Full Text Available RESUMEN: A partir de los enfoques sobe Expansionismo-Revanchismo de Elizondo y las Imágenes en Espejo de Scott, se analizaron los contenidos de blogs referentes a imágenes mutuas entre Perú y Chile, comprendidos a partir de la fecha (16-01-2008 de presentación por parte del Perú de la Demanda ante el Tribunal de la Haya para la solución del Diferendo Limítrofe con Chile, hasta el 30-03-2011. Se han registrado intensas y variadas manifestaciones de hostilidad mutua, que respaldan la vigencia de la dinámica Expansionismo-Revanchismo en las imágenes mutuas entre Chile y Perú en los blogs analizados. Paralelamente, se detectaron contenidos correspondientes a actitudes integracionistas entre ambos países. Los resultados fundamentan la utilidad del enfoque de las Imágenes en Espejo como instrumento para el análisis de contenido de blogs portadores de mensajes de hostilidad e integración entre ambos países. Se propone una estrategia psicosocial binacional para desactivar la dinámica Expansionismo- revanchismo que contribuiría a producir catastróficas consecuencias para las generaciones actuales y futuras de ambos países; y, promover la integración fronteriza entre Tacna (Perú y Arica (Chile. ABSTRACT: The contents of blogs relating to mutual images between Peru and Chile were analyzed from the approaches about Expansionism – Revanchism of Elizondo, and The images on the mirror of Scott, included the date of the presentation (January 16th, 2008 by Peru of the demand before the International Court of Justice at the Hague for the solution of the border dispute with Chile until March 30th, 2011. There have been intense and varied manifestations of mutual hostility that support the validity of Expansionism-Revanchism dynamics in the mutual images between Chile and Peru in the analyzed blogs. At the same time, it was detected content corresponding to integrationist attitudes between the two countries. The results underlie the utility

  14. L’ICF-CY per la progettazione inclusiva per gli alunni con DSA

    Directory of Open Access Journals (Sweden)

    Marina Chiaro

    2013-09-01

    Full Text Available Il lavoro presenta i principali risultati di una ricerca a carattere teorico-esplorativo, finalizzata a valutare quanto lo strumento dell’International Classification of Functioning, Disability and Health for Children and Youth (ICF-CY sia conosciuto ed utilizzato nei diversi contesti educativi per l’osservazione degli allievi e del loro “funzionamento” in senso dinamico-evolutivo, in interazione con i fattori ambientali, e finalizzato ad una progettazione educativo-didattica significativamente orientata alla prospettiva inclusiva. A tal fine sono stati intervistati gli insegnanti delle scuole di ogni ordine e grado del Lazio iscritti al Master in Didattica e Psicopedagogia per gli alunni con Disturbi Specifici di Apprendimento (DSA presso l’Università degli Studi di Roma Tre. La scelta è coerente con la direttiva MIUR del 2012 dove viene considerato rilevante ai fini della individuazione dei Bisogni Educativi Speciali dell’alunno, ed in particolare degli allievi con DSA, l’apporto, anche sul piano culturale del modello diagnostico ICF-CY che considera la persona nella sua totalità, in una prospettiva bio-psico-sociale.

  15. L’otto per mille nella nuova relazione della Corte dei Conti: spunti per una riforma

    Directory of Open Access Journals (Sweden)

    Giuseppe Casuscelli

    2015-12-01

    Full Text Available A chiare lettere - Transizioni   La Corte dei Conti - organo neutrale, autonomo e indipendente sia dal Governo sia dal Parlamento, con il compito istituzionale di sottoporre a controllo la gestione delle risorse pubbliche allo scopo di “perseguire l’utilizzo appropriato ed efficace dei fondi pubblici, la ricerca di una gestione finanziaria rigorosa, la regolarità dell’azione amministrativa e l’informazione dei poteri pubblici e della popolazione tramite la pubblicazione di relazioni obiettive” -, per la seconda volta ha reso pubblica, di agevole accesso e di piana comprensione la «Relazione concernente la “Destinazione e gestione dell'8 per mille: le misure consequenziali finalizzate alla rimozione delle disfunzioni rilevate”». Così facendo, la Corte ha osservato in concreto la regola dell’efficienza e della trasparenza amministrativa, e ha proseguito nell'intento informativo avviato con la pubblicazione della relazione dello scorso anno, confermandolo e rafforzandolo.

  16. Parallel search engine optimisation and pay-per-click campaigns: A comparison of cost per acquisition

    Directory of Open Access Journals (Sweden)

    Wouter T. Kritzinger

    2017-01-01

    Full Text Available Background: It is imperative that commercial websites should rank highly in search engine result pages because these provide the main entry point to paying customers. There are two main methods to achieve high rankings: search engine optimisation (SEO and pay-per-click (PPC systems. Both require a financial investment – SEO mainly at the beginning, and PPC spread over time in regular amounts. If marketing budgets are applied in the wrong area, this could lead to losses and possibly financial ruin.Objectives: The objective of this research was to investigate, using three real-world case studies, the actual expenditure on and income from both SEO and PPC systems. These figures were then compared, and specifically, the cost per acquisition (CPA was used to decide which system yielded the best results.Methodology: Three diverse websites were chosen, and analytics data for all three were compared over a 3-month period. Calculations were performed to reduce the figures to single ratios, to make comparisons between them possible.Results: Some of the resultant ratios varied widely between websites. However, the CPA was shown to be on average 52.1 times lower for SEO than for PPC systems.Conclusion: It was concluded that SEO should be the marketing system of preference for e-commerce-based websites. However, there are cases where PPC would yield better results – when instant traffic is required, and when a large initial expenditure is not possible.

  17. Per una teoria politica dell’impresa cooperativa

    National Research Council Canada - National Science Library

    Stefano Zan

    2014-01-01

    Il saggio propone una traccia di ricerca per l’elaborazione di una teoria politica della cooperazione, ovvero per la considerazione del fenomeno cooperativo come caratterizzato da una peculiare modalità...

  18. Per-patient-per-month drug costs in Medicare Part D protected classes.

    Science.gov (United States)

    Mucha, Lisa; Masia, Neal A; Axelsen, Kirsten J

    2006-01-01

    The objective of this study was to estimate the per-patient-per-month (PPPM) costs of medications in the six Medicare Part D protected classes based on findings among Medicare and dual eligible beneficiaries with drug coverage before the enactment of the benefit. Data were from the Thomson Medstat MarketScan Medicare and Medicaid claims databases. The study sample was constructed by identifying patients who were enrolled either in Medicare or dually in Medicare and Medicaid. PPPM costs were calculated for each protected class. Drugs covered under Part B were excluded. PPPM aggregated costs within each class. The classes in which generic formulations are available (antidepressants and anticonvulsants) show low PPPM costs ($ US 45.31 and $ US 50.97, respectively). The most expensive class is the antiretrovirals ($ US 829.73). This class is the costliest for all dual eligible patients including those aged 64 years and under. Among the dual eligible aged 65 years and older, the immunosuppressants are the most expensive class. The same result is seen qualitatively in the Medicare group. PPPM costs are not uniformly high among the protected classes. The claims data in this study allowed a 'real world' check of how much the protected classes may impact the finances of Part D. There are differences within the classes between the dual eligible and Medicare patients, and also within the dual eligible by age. This is an important message to policy makers that a change to the structure of the protected classes in Part D may have differential effects across classes and also within classes.

  19. 38 CFR 61.31 - Application for per diem.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Application for per diem. 61.31 Section 61.31 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.31 Application for per diem. (a) To apply for...

  20. 33 CFR 5.57 - Traveling expenses and per diem.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Traveling expenses and per diem... GENERAL COAST GUARD AUXILIARY § 5.57 Traveling expenses and per diem. A member of the Auxiliary, when assigned to specific duties, may be paid actual necessary traveling expenses, including a per diem...

  1. 36 CFR 1150.48 - PER: Citation, answer, amendment.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false PER: Citation, answer...; Pleadings and Motions § 1150.48 PER: Citation, answer, amendment. (a) Unless otherwise specified, other..., the citation shall request PER when it appears to the Executive Director that immediate and...

  2. Activating PER repressor through a DBT-directed phosphorylation switch.

    Directory of Open Access Journals (Sweden)

    Saul Kivimäe

    2008-07-01

    Full Text Available Protein phosphorylation plays an essential role in the generation of circadian rhythms, regulating the stability, activity, and subcellular localization of certain proteins that constitute the biological clock. This study examines the role of the protein kinase Doubletime (DBT, a Drosophila ortholog of human casein kinase I (CKIepsilon/delta. An enzymatically active DBT protein is shown to directly phosphorylate the Drosophila clock protein Period (PER. DBT-dependent phosphorylation sites are identified within PER, and their functional significance is assessed in a cultured cell system and in vivo. The per(S mutation, which is associated with short-period (19-h circadian rhythms, alters a key phosphorylation target within PER. Inspection of this and neighboring sequence variants indicates that several DBT-directed phosphorylations regulate PER activity in an integrated fashion: Alternative phosphorylations of two adjoining sequence motifs appear to be associated with switch-like changes in PER stability and repressor function.

  3. Mentalità stratigrafica e progetti per la conoscenza e per la conservazione

    Directory of Open Access Journals (Sweden)

    Pertot, Gianfranco

    2002-12-01

    Full Text Available The present work is made to show a didactic experience acquired by the authors at the Universities of Milan and Brescia (Italy in the sphere of teaching Architectural Restoration. The peculiar aspect of research is the attempt to apply not only the procedures of archeological stratigraphy but also the “stratigraphical mentality” to the project of conservation and re-use of architecture. Introducing and using, for example, new models of archeological stratigraphy lecture of the buildings expressed for the requirements of conservation and re-use, in proposing the new index-codes of Phases Intersides and Associated Stratigraphical Unity. The authors finally put forward some comments about the so called “archaological” Restoration.Gli autori presentano i risultati più significativi di una ricerca svolta presso le Università di Milano e di Brescia, nell’ambito dei corsi di Restauro architettonico. Fra i principali obiettivi dello studio e delle esperienze didattiche correlate vi è il tentativo non solo di utilizzare le procedure dell’archeologia stratigrafica, per quanto utile e possibile, nella complessa serie di operazioni che segna la redazione di un progetto di conservazione e di riuso, ma di trasferirvi anche quella che si può definire come “mentalità stratigrafica”. In particolare considerando nuovi codici, quali le Interfacce di Fase e le Unità Stratigrafiche Associate. A corredo di queste argomentazioni vengono anche svolte alcune considerazioni in merito al cosiddetto “Restauro archeologico”

  4. Visitantes florais de Lagerstroemia speciosa Pers: (Lythraceae Floral visitors in Lagerstroemia speciosa Pers: (Lythraceae

    Directory of Open Access Journals (Sweden)

    Maria de Jesus Vitali-Veiga

    1999-06-01

    Full Text Available Studies were carried out with Lagerstroemia speciosa Pers. on floral reproductive systems, diversity and constancy of visiting insects at different hours of day, the behaviour of these insects at the flowers and the influence of these environmental factors in relation to their visits. The fenology, anthesis and others particularity of this vegetal species was studied. A great diversity of insects was verified visiting the flowers with the predominance of bees. The most frequent and constant species encountered were: Nannotrigona testaceicornis (Lepeletier, 1836 (40,2%, Tetragonisca angustula (Latreille, 1811 (16,9%, Apis mellifera Linnaeus, 1758 (11,8%, Plebeia droryana (Friese, 1900 (9,1 % e Exomalopsis fulvofasciata (Smith, 1879 (8,5%. The blossoms possessis features of melittophily syndrome and diurnal anthesis. The environmental factors influence the insects foraging activity, mainly temperature, light, time of day, humidity and wind speed. The effective pollinators were the large insects like Bombus morio (Swederus, 1787, Bombus atratus (Franklin, 1913, Centris tarsata (Smith, 1874, Centris flavifrons Fabricius, 1775, Xylocopa suspecta Camargo & Moure, 1988, Xylocopa frontalis (Olivier, 1789 and Eulaema nigrita Lepeletier, 1841.

  5. Collapse transition in polymer models with multiple monomers per site and multiple bonds per edge

    Science.gov (United States)

    Rodrigues, Nathann T.; Oliveira, Tiago J.

    2017-12-01

    We present results from extensive Monte Carlo simulations of polymer models where each lattice site can be visited by up to K monomers and no restriction is imposed on the number of bonds on each lattice edge. These multiple monomer per site (MMS) models are investigated on the square and cubic lattices, for K =2 and 3, by associating Boltzmann weights ω0=1 , ω1=eβ1 , and ω2=eβ2 to sites visited by 1, 2, and 3 monomers, respectively. Two versions of the MMS models are considered for which immediate reversals of the walks are allowed (RA) or forbidden (RF). In contrast to previous simulations of these models, we find the same thermodynamic behavior for both RA and RF versions. In three dimensions, the phase diagrams, in space β2×β1 , are featured by coil and globule phases separated by a line of Θ points, as thoroughly demonstrated by the metric νt, crossover ϕt, and entropic γt exponents. The existence of the Θ lines is also confirmed by the second virial coefficient. This shows that no discontinuous collapse transition exists in these models, in contrast to previous claims based on a weak bimodality observed in some distributions, which indeed exists in a narrow region very close to the Θ line when β1<0 . Interestingly, in two dimensions, only a crossover is found between the coil and globule phases.

  6. Bacillus licheniformis Contains Two More PerR-Like Proteins in Addition to PerR, Fur, and Zur Orthologues.

    Directory of Open Access Journals (Sweden)

    Jung-Hoon Kim

    Full Text Available The ferric uptake regulator (Fur family proteins include sensors of Fe (Fur, Zn (Zur, and peroxide (PerR. Among Fur family proteins, Fur and Zur are ubiquitous in most prokaryotic organisms, whereas PerR exists mainly in Gram positive bacteria as a functional homologue of OxyR. Gram positive bacteria such as Bacillus subtilis, Listeria monocytogenes and Staphylococcus aureus encode three Fur family proteins: Fur, Zur, and PerR. In this study, we identified five Fur family proteins from B. licheniformis: two novel PerR-like proteins (BL00690 and BL00950 in addition to Fur (BL05249, Zur (BL03703, and PerR (BL00075 homologues. Our data indicate that all of the five B. licheniformis Fur homologues contain a structural Zn2+ site composed of four cysteine residues like many other Fur family proteins. Furthermore, we provide evidence that the PerR-like proteins (BL00690 and BL00950 as well as PerRBL (BL00075, but not FurBL (BL05249 and ZurBL (BL03703, can sense H2O2 by histidine oxidation with different sensitivity. We also show that PerR2 (BL00690 has a PerR-like repressor activity for PerR-regulated genes in vivo. Taken together, our results suggest that B. licheniformis contains three PerR subfamily proteins which can sense H2O2 by histidine oxidation not by cysteine oxidation, in addition to Fur and Zur.

  7. Exemple de volumetria per retrocés

    OpenAIRE

    Fuguet i Jordà, Elisabet; Giménez López, Estela; Jaumot Soler, Joaquim; Núñez Burcio, Oscar; Serrano i Plana, Núria; Tarancón Sanz, Alex

    2013-01-01

    Aquest material forma part d'una col•lecció de tres vídeos, que estan creats per tal de mostrar a l'alumne de Química Analítica la diferència que hi ha entre una volumetria directa, una volumetria indirecta i una volumetria per retrocés. En aquest vídeo es mostra la volumetria per retrocés.

  8. Roars: sette proposte per la valutazione della ricerca

    Directory of Open Access Journals (Sweden)

    Maria Chiara Pievatolo

    2012-06-01

    Full Text Available L’articolo uscito oggi su Roars, Sette proposte per la VQR, propone sette soluzioni facilmente praticabili per correggere gli aspetti più discutibili della valutazione della ricerca in corso in Italia.  In queste pagine abbiamo discusso molto della classificazioni non bibliometriche delle riviste e abbiamo presentato una nostra soluzione a lungo termine. Nel breve termine pensiamo però [...

  9. Nova via terapèutica per tractar desordres gastrointestinals

    OpenAIRE

    Martínez, Vicente

    2009-01-01

    El tractament de les alteracions funcionals gastrointestinals, encapçalades per la síndrome del còlon irritable, és un repte més per a la biomedicina. L’article següent presenta una possible via terapèutica: bloquejar un dels receptors de la vasopresina, una de les hormones encarregades de generar respostes orgàniques per mitigar els efectes nocius de l’estrès o estats depressius. Sembla contradictori interrompre una funció hormonal tan beneficiosa, però estudis previs han demostrat que les p...

  10. PER1 Phosphorylation Specifies Feeding Rhythm in Mice

    Directory of Open Access Journals (Sweden)

    Zhiwei Liu

    2014-06-01

    Full Text Available Organization of circadian behavior, physiology, and metabolism is important for human health. An S662G mutation in hPER2 has been linked to familial advanced sleep-phase syndrome (FASPS. Although the paralogous phosphorylation site S714 in PER1 is conserved in mice, its specific function in circadian organization remains unknown. Here, we find that the PER1S714G mutation accelerates the molecular feedback loop. Furthermore, hPER1S714G mice, but not hPER2S662G mice, exhibit peak time of food intake that is several hours before daily energy expenditure peaks. Both the advanced feeding behavior and the accelerated clock disrupt the phase of expression of several key metabolic regulators in the liver and adipose tissue. Consequently, hPER1S714G mice rapidly develop obesity on a high-fat diet. Our studies demonstrate that PER1 and PER2 are linked to different downstream pathways and that PER1 maintains coherence between the circadian clock and energy metabolism.

  11. Bacterial PerO Permeases Transport Sulfate and Related Oxyanions.

    Science.gov (United States)

    Hoffmann, Marie-Christine; Pfänder, Yvonne; Tintel, Marc; Masepohl, Bernd

    2017-07-15

    Rhodobacter capsulatus synthesizes the high-affinity ABC transporters CysTWA and ModABC to specifically import the chemically related oxyanions sulfate and molybdate, respectively. In addition, R. capsulatus has the low-affinity permease PerO acting as a general oxyanion transporter, whose elimination increases tolerance to molybdate and tungstate. Although PerO-like permeases are widespread in bacteria, their function has not been examined in any other species to date. Here, we present evidence that PerO permeases from the alphaproteobacteria Agrobacterium tumefaciens , Dinoroseobacter shibae , Rhodobacter sphaeroides , and Sinorhizobium meliloti and the gammaproteobacterium Pseudomonas stutzeri functionally substitute for R. capsulatus PerO in sulfate uptake and sulfate-dependent growth, as shown by assimilation of radioactively labeled sulfate and heterologous complementation. Disruption of perO genes in A. tumefaciens , R. sphaeroides , and S. meliloti increased tolerance to tungstate and, in the case of R. sphaeroides , to molybdate, suggesting that heterometal oxyanions are common substrates of PerO permeases. This study supports the view that bacterial PerO permeases typically transport sulfate and related oxyanions and, hence, form a functionally conserved permease family. IMPORTANCE Despite the widespread distribution of PerO-like permeases in bacteria, our knowledge about PerO function until now was limited to one species, Rhodobacter capsulatus In this study, we showed that PerO proteins from diverse bacteria are functionally similar to the R. capsulatus prototype, suggesting that PerO permeases form a conserved family whose members transport sulfate and related oxyanions. Copyright © 2017 American Society for Microbiology.

  12. The Hepatitis C Genotype 1 Paradox: Cost per Treatment Is Increasing, but Cost per Cure Is Decreasing

    Directory of Open Access Journals (Sweden)

    Stephen D Shafran

    2015-01-01

    Full Text Available Significant attention has been focused on the perceived increase in the cost of antiviral treatment for hepatitis C genotype 1 infection since the approval of the first direct-acting antiviral agents in 2011. Using Canadian list prices, the present analysis points out a paradox: while the cost per antiviral regimen is increasing, the cost per cure is decreasing, especially with interferon-free therapy. In a publicly funded health care system, the lowest cost per cure is a more valuable measure of value for public money than the cost per regimen.

  13. Le immagini nei libri di storia per la scuola primaria

    Directory of Open Access Journals (Sweden)

    Maila Pentucci

    2015-09-01

    Full Text Available Il presente saggio, a partire dall’analisi di un corpus di libri di storia per la scuola primaria, vuole comprendere come e quanto le immagini possano essere portatrici di sapere e quanto invece possano ingenerare stereotipi e misconoscenze negli alunni. Le pagine dei manuali sono sempre più ricche di elementi iconografici, probabilmente per rispondere alla modalità di apprendimento simultanee e proprie dei ragazzi dell’era digitale. Tuttavia questi elementi non sono autopoietici rispetto al sapere storico, ma richiedono una didattica specializzata per la loro decodifica ed interpretazione. Le immagini, infatti, possono essere utilizzate come fonti, secondo metodologie di ricerca laboratoriale, oppure possono essere mediatori di saperi storici, ovvero strumenti portatori di operazioni significative finalizzate allo sviluppo di competenze. Spesso però negli usi editoriali sono poco significative sul piano cognitivo, non utili al docente per una trasposizione didattica che metta gli alunni nella condizione di pensare storicamente.

  14. 78 FR 46421 - Proposed Information Collection (Per Diem for Nursing Home Care of Veterans in State Homes; Per...

    Science.gov (United States)

    2013-07-31

    ... AFFAIRS Proposed Information Collection (Per Diem for Nursing Home Care of Veterans in State Homes; Per Diem for Adult Day Care of Veterans in State Homes): Comment Request AGENCY: Veterans Health... home and adult day health services care to Veterans. VA requires facilities providing nursing home and...

  15. 77 FR 45719 - Proposed Information Collection (Per Diem for Nursing Home Care of Veterans in State Homes; Per...

    Science.gov (United States)

    2012-08-01

    ... Information Collection (Per Diem for Nursing Home Care of Veterans in State Homes; Per Diem for Adult Day Care... solicits comments on information needed to ensure that nursing home and adult day health care facilities... services care to Veterans. VA requires facilities providing nursing home and adult day health care to...

  16. The Impact of Corruption on GDP Per Capita

    Directory of Open Access Journals (Sweden)

    Nazar Mustapha

    2014-10-01

    Full Text Available The paper studies the impact of corruption on the GDP per capita. A panel data covers the period between 2003 and 2011. The objective is to test the hypothesis that there is a strong negative impact of corruption on the GDP per capita. Three tests were conducted, the pool OLS, The Fixed Effect and the Random effect estimations. The main result of this study is that all three tests had shown strong statistically significant negative impact of corruption on the GDP per capita.

  17. Avaluació dels indicadors per mesurar la pobresa multidimensional

    OpenAIRE

    Permanyer, Iñaki

    2015-01-01

    Tradicionalment mesurat en base als ingressos, actualment el concepte de pobresa inclou altres dimensions rellevants per al benestar de les persones, com ara l’educació o la salut. Aquest article revisa les diferents propostes de mesura de pobresa multidimensional i mostra que, per a aquells individus classificats com a “pobres”, si tenen atributs que estan per sobre del llindar de la pobresa, aquests no poden influir en l’avaluació global dels nivells de privació. L’autor conclou recomanant ...

  18. Taccio e cionco: due parole Toscane per forfè

    Directory of Open Access Journals (Sweden)

    Bruno Migliorini

    1972-12-01

    Full Text Available Documentato in Toscana fin clal sec. XIV (Leonardo Frescobalcli nella locuzione tenere a taccio «per un prezzo convenuto», poi attestato dal Cinquecento al Settecento a Firenze e a Pisa (Cecchi, Fagiuoli, Ga­ bella di Pisa e tuttora vivo qua e là in Toscana nella locuzione fare un taccio «combinare per un prezzo globale», questo taccio è stato clapprima etimologizzato dal Caix, Studi di efimologia italiana e romanza, Firenze 1878, § 615: Taccio 'cottimo'; fare un taccio 'finir una controversia con accomoclamento'. Per ' fascia da faxare 'tassare, stimare, computare'.

  19. Il calcolo del premio assicurativo per gli eventi catastrofali

    OpenAIRE

    Aversa, Monica

    2010-01-01

    Tra i problemi che pone la Matematica Attuariale ha un rilievo non indifferente la questione del calcolo del premio, ovvero il prezzo da far pagare all’assicurato per garantirgli la copertura assicurativa. Nella presente tesi si esaminano i più moderni principi di calcolo del premio per le assicurazioni danni, in particolare si considerano i rischi catastrofali e si utilizza come modello per il rischio “il danno cumulato” ovvero la variabile casuale S=X1+X2+…..+XN, con Xi≥0 variabili casuali ...

  20. Pluto Moons exhibit Orbital Angular Momentum Quantization per Mass

    Directory of Open Access Journals (Sweden)

    Potter F.

    2012-10-01

    Full Text Available The Pluto satellite system of the planet plus five moons is shown to obey the quan- tum celestial mechanics (QCM angular momentum per mass quantization condition predicted for any gravitationally bound system.

  1. Ultrasonographic evaluation of first trimester bleeding per vaginum

    OpenAIRE

    Neelam Gupta; Meenakshi Samariya; Devika Choudhary; Kanti Yadav; Pushpa Kannoujiya

    2016-01-01

    Background: First trimester is a very crucial period of pregnancy having high risks of pregnancy losses. The objective of this study was to assess the accuracy of ultrasound in diagnosis of cause of first trimester bleeding per vaginum. Methods: 200 women who attended the out-patient department with the complaint of bleeding per vagina in the first trimester pregnancy were taken for the study. Clinical assessment by pelvic examination was done and a provisional diagnosis was made. All nece...

  2. Substrate control through per-O-methylation of cyclodextrin acids

    DEFF Research Database (Denmark)

    Fenger, Thomas H; Bols, Mikael

    2010-01-01

    Per-O-methylated cyclodextrins containing a single 2-O-(2-acetate), 2-O-(3-propanoate) or a 6-carboxylate were investigated for glycosidase activity on p-nitrophenyl glycosides. The former two compounds displayed enzyme catalysis giving rate accelerations of 500-1000, while the latter compound gave...... marginal catalysis. These results show that per-O-methylated cyclodextrins direct substrate binding from the secondary face leading to better catalysis....

  3. Distribution Dynamics of Regional GDP per Employee in Unified Germany

    OpenAIRE

    Vollmer, Sebastian; Holzmann, Hajo; Ketterer, Florian; Klasen, Stephan

    2010-01-01

    We investigate to what extent convergence in production levels per worker has been achieved in Germany since unification. To this end, we model the distribution of GDP per employee across German districts using two-component normal mixtures. While in the first year after unification, the two-component distributions were clearly separated and bimodal, corresponding to the East and West German districts, respectively, in the following years they started to merge showing only one mode. Still, us...

  4. Time-place learning and memory persist in mice lacking functional Per1 and Per2 clock genes.

    Science.gov (United States)

    Mulder, C; Van Der Zee, E A; Hut, R A; Gerkema, M P

    2013-12-01

    With time-place learning, animals link a stimulus with the location and the time of day. This ability may optimize resource localization and predator avoidance in daily changing environments. Time-place learning is a suitable task to study the interaction of the circadian system and memory. Previously, we showed that time-place learning in mice depends on the circadian system and Cry1 and/or Cry2 clock genes. We questioned whether time-place learning is Cry specific or also depends on other core molecular clock genes. Here, we show that Per1/Per2 double mutant mice, despite their arrhythmic phenotype, acquire time-place learning similar to wild-type mice. As well as an established role in circadian rhythms, Per genes have also been implicated in the formation and storage of memory. We found no deficiencies in short-term spatial working memory in Per mutant mice compared to wild-type mice. Moreover, both Per mutant and wild-type mice showed similar long-term memory for contextual features of a paradigm (a mild foot shock), measured in trained mice after a 2-month nontesting interval. In contrast, time-place associations were lost in both wild-type and mutant mice after these 2 months, suggesting a lack of maintained long-term memory storage for this type of information. Taken together, Cry-dependent time-place learning does not require Per genes, and Per mutant mice showed no PER-specific short-term or long-term memory deficiencies. These results limit the functional role of Per clock genes in the circadian regulation of time-place learning and memory.

  5. Classical capacity per unit cost for quantum channels

    Science.gov (United States)

    Jarzyna, Marcin

    2017-09-01

    In most communication scenarios, sending a symbol encoded in a quantum state requires spending resources such as energy, which can be quantified by a cost of communication. A standard approach in this context is to quantify the performance of communication protocol by classical capacity, quantifying the maximal amount of information that can be transmitted through a quantum channel per single use of the channel. However, different figures of merit are also possible and a particularly well-suited one is the classical capacity per unit cost, which quantifies the maximal amount of information that can be transmitted per unit cost. I generalize this concept to account for the quantum nature of the information carriers and communication channels and show that if there exists a state with cost equal to zero, e.g., a vacuum state, the capacity per unit cost can be expressed by a simple formula containing maximization of the relative entropy between two quantum states. This enables me to analyze the behavior of photon information efficiency for general communication tasks and show simple bounds on the capacity per unit cost in terms of quantities familiar from quantum estimation theory. I calculate also the capacity per unit cost for general Gaussian quantum channels.

  6. Alstroemeriaceae en Perú y áreas vecinas

    Directory of Open Access Journals (Sweden)

    Anton Hofreiter

    2006-10-01

    Full Text Available Las Alstroemeriaceae peruanas fueron revisadas por última vez por Killip (1936. Es necesaria una nueva revisión. Cinco viajes de campo de varias semanas cada uno fueron emprendidos a Sudamérica con el fin de estudiar las plantas in situ. En el presente trabajo se describe la historia taxonómica y colección de los géneros con especial énfasis en el Perú. El área descrita no considera fronteras políticas sino unidades geográficas de acuerdo a Baumann (1988, Berry (1982, Duellman (1979, Simpson (1975, 1979 y Weigend (2002. Se reconocen cinco unidades geográficas: Región Amotape-Huancabamba (Ecuador, Perú, Cordillera Occidental (Perú, Cordillera Central (Perú, Cordillera Oriental (Bolivia, Perú y el Altiplano (Bolivia, Perú. Se brinda una clave taxonómica en inglés y español para determinar las especies del Perú. Para cada una de las especies se discute la forma típica de crecimiento y su variabilidad, preferencias de hábitat y distribución general. Se identifican las especies de Ruiz & Pavón (1802. Ellos describieron en su Flora de Chile y Perú 23 especies de Alstroemeria, 18 fueron de Perú, ahora 17 son incluidas en Bomarea, todas proceden de Perú. El género Bomarea está subdividido en 4 subgéneros: Baccata, Bomarea s. str., Sphaerine y Winchurea (Hofreiter & Tillich, 2002. Alstroemeria no es dividido en subgéneros, pero existen dos grupos reconocidos, Alstroemeria de Chile y Brasil. En el área de estudio se encuentran dos especies de Alstroemeria y 68 de Bomarea, de ellas 43 especies pertenecen al subgénero Bomarea, 9 especies al subgénero Sphaerine y 16 especies al subgénero Wichuraea. El subgénero Baccata no se encuentra en el área de estudio. Seis de las especies del género Bomarea son nuevas para la ciencia: B. amazonica, B. libertadensis, B. lopezii, B. macusanii, B. pseudopurpurea, B. weigendii.

  7. Potential of soil liquefaction at Perlis, northern region of Malalysia

    Science.gov (United States)

    Ghazaly, Zuhayr Md; Rahim, Mustaqqim Abdul; Nasir, Mohamad Amzar Bin Mhd; Isa, Nur Fitriah; Zaki, Mohd Faiz Mohammad; Hassan, Zulkarnain Bin; Ismail, Zul-Atfi Bin

    2017-09-01

    Soil liquefaction is earthquake's secondary effect which could cause fatal damages and structures instability. Despite Malaysia been located in stable zone of Pacific Ring of Fire, few significant surrounded quakes like Sumatra-Andaman earthquake had prompted Malaysian's public concern, especially in Perlis area, on local seismic resistant. Hence, this research presents the analysis result of liquefaction potential of the soils, as the secondary effect of earthquake, within Perlis, northern region of Malaysia; the next strong and sustainable metropolis by using semi-empirical procedures introduced by Seed and Idriss. The study consists of two stages which were determination of the local geological and geotechnical site conditions within Perlis and analysis of soil liquefaction susceptibility by using various methods and liquefaction potential by using Simplified Procedure developed by Seed and Idriss on stress approach. There were consist of four phases implemented in order to achieve the objectives targeted for the study after problem being identified. Firstly, a comprehensive review of literature on liquefaction at Perlis was carried out. Second phase was data collection process that includes collection of Site Investigation (SI) report. Thirdly, data analysis was carried out by utilizing suitable method. The final phase was to draw conclusion and recommendation for this study. It can be concluded that the overall Perlis due to earthquake moment magnitude below 7.5 has no potential to soil liquefaction. However, with the range of liquefaction potential of 1.60 to 5.64 in Kuala Perlis area, it is liquefiable. The development of liquefaction severity map of Perlis, Malaysia in this research, may be used by others as a reference for seismic design and standard safety measures as well as for further research work.

  8. Strong sales growth in 2006: + 21 per cent

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    Paris, February 14, 2007 - The Gaz de France group today reported record consolidated sales of euro 27,642 million in 2006, up 21 per cent compared with 2005. Under average weather conditions and comparable accounting methods, sales increased by 24 per cent versus 2005. This growth results primarily from an overall increase in European energy prices notwithstanding the slight decrease in prices towards the end of the year. The group also benefited from an increase in volumes and from the integration of new operations. After a colder first half of the year compared to that of the previous year, the autumn of 2006 was particularly warm. This had a negative impact on sales growth (there was a 12 billion kWh decrease between 2005 and 2006). The sales generated by the group's international activities increased by 33 per cent to a total of euro 10,839 m in 2006 and now account for almost 40 per cent of the group's overall sales. In this context, the group confirmed at the board meeting held on January 23, 2007 that it would reach the targets set for 2006, namely: - Growth in EBITDA above 20 per cent, e.g. in excess of euro 5 billion, - Net income of more than euro 2.2 billion.

  9. Estimation of optimal educational cost per medical student.

    Science.gov (United States)

    Yang, Eunbae B; Lee, Seunghee

    2009-09-01

    This study aims to estimate the optimal educational cost per medical student. A private medical college in Seoul was targeted by the study, and its 2006 learning environment and data from the 2003~2006 budget and settlement were carefully analyzed. Through interviews with 3 medical professors and 2 experts in the economics of education, the study attempted to establish the educational cost estimation model, which yields an empirically computed estimate of the optimal cost per student in medical college. The estimation model was based primarily upon the educational cost which consisted of direct educational costs (47.25%), support costs (36.44%), fixed asset purchases (11.18%) and costs for student affairs (5.14%). These results indicate that the optimal cost per student is approximately 20,367,000 won each semester; thus, training a doctor costs 162,936,000 won over 4 years. Consequently, we inferred that the tuition levels of a local medical college or professional medical graduate school cover one quarter or one-half of the per- student cost. The findings of this study do not necessarily imply an increase in medical college tuition; the estimation of the per-student cost for training to be a doctor is one matter, and the issue of who should bear this burden is another. For further study, we should consider the college type and its location for general application of the estimation method, in addition to living expenses and opportunity costs.

  10. Turbo-per-Tone Equalization for ADSL Systems

    Directory of Open Access Journals (Sweden)

    Marc Moonen

    2005-05-01

    Full Text Available We study the equalization procedure in discrete multitone (DMT-based systems, in particular, in DMT-based ADSL systems. Traditionally, equalization is performed in the time domain by means of a channel shortening filter. Shifting the equalization operations to the frequency domain, as is done in per-tone equalization, increases the achieved bitrate by 5–10%. We show that the application of the turbo principle to per-tone equalization can provide significant additional gains. In the proposed receiver structure, referred to as a “turbo-per-tone equalization” structure, equalization and decoding are performed in an iterative fashion. Equalization is done by means of a linear minimum mean squared error (MMSE equalizer, using a priori information. We give a description of an efficient implementation of such an equalizer in the per-tone structure. Simulations show that we obtain a bitrate increase of 12–16% compared to the original per-tone equalization-based receiver structure.

  11. HiPER: The European path to laser energy

    Directory of Open Access Journals (Sweden)

    Edwards Chris

    2013-11-01

    Full Text Available While for decades, energy production relying on laser inertial fusion has been a strong motivation for the development in Europe of a few high-energy laser facilities and dedicated scientific programs, the HiPER initiative launched in 2004 fostered an ambitious large-scale coordinated European program toward inertial fusion energy. Anticipating the successful demonstration of fusion ignition and gain at the National Ignition Facility (NIF in the USA, scientists and engineers from across Europe are developing the case for a next generation laser fusion facility, HiPER, to be constructed in Europe. The single-facility build strategy of HiPER (High Power Laser Energy Research Facility aims at first demonstrating some key elements of a fusion reactor in a high rep-rate few-second cycle mode, before addressing energy production on a high rep-rate continuous mode in a second area.

  12. La Psoralea bituminosa evoluciona per defensar-se

    OpenAIRE

    Espadaler, Xavier

    2008-01-01

    Quan la formiga Messor barbarus remou selectivament les llavors de la Psoralea bituminosa podria estar canviant l'estructura de la població d'aquestes plantes. Per això, l'objectiu de l'estudi següent ha estat determinar empíricament la preferència d'aquestes formigues granívores per les llavors que potser eren més pesants, però sobretot menys dures. Els resultats són contundents: prop d'un 70% amb més duresa no són consumides. A més, com són dispersades lluny de la planta originària, les gen...

  13. Projecte TRAMA. Formació per al treball en xarxa.

    Directory of Open Access Journals (Sweden)

    Daniel Muntané

    2008-12-01

    Full Text Available Aquest article vol exposar el treball de recerca i de construcció del coneixement sobre la docència del treball en xarxa dut a terme durant dos anys per les facultats d’educació de les universitats catalanes. El projecte d’educació i treball en xarxa (TRAMA té per objectiu promoure la formació inicial dels professionals dels àmbits socioeducatius en treball en xarxa i l'impuls d'estratègies de treball integrat per donar resposta als reptes que la societat actualmente planteja a l'educació. Aquest projecte se centra en la sensibilització del professorat universitari i la inclusió dels aspectes relacionats amb el treball en xarxa en el currículum de la formació inicial dels professionals de l'àmbit socioeducatiu.

  14. Le TIC nella scuola: dieci raccomandazioni per i policy maker

    Directory of Open Access Journals (Sweden)

    Antonio Calvani

    2013-12-01

    Full Text Available Basandosi sulle evidenze relative al rapporto tra tecnologia e apprendimento e sul recente rapporto OCSE riguardante il Piano Nazionale Scuola Digitale, l’autore riflette sui criteri che devono orientare le politiche innovative, ispirati a sostenibilità, ottimizzazione dell’impatto educativo, sottolineando anche la necessità di finalizzare meglio l’impiego delle tecnologie verso specifici obiettivi. Viene ricordato come storicamente si tenda a sovrastimare l’effetto positivo delle tecnologie sull’apprendimento; la ricerca ha invece rilevato i limiti della loro efficacia (da ricercare in determinate aree e la rilevanza del rischio del sovraccarico cognitivo che la loro introduzione può comportare. Si propongono alcuni suggerimenti per i decisori scolastici rispondendo alle due domande “Quali criteri per la politica tecnologica?”, “In che modo usare le tecnologie per apprendere a scuola?”.

  15. Quantum search with multiple walk steps per oracle query

    Science.gov (United States)

    Wong, Thomas G.; Ambainis, Andris

    2015-08-01

    We identify a key difference between quantum search by discrete- and continuous-time quantum walks: a discrete-time walk typically performs one walk step per oracle query, whereas a continuous-time walk can effectively perform multiple walk steps per query while only counting query time. As a result, we show that continuous-time quantum walks can outperform their discrete-time counterparts, even though both achieve quadratic speedups over their corresponding classical random walks. To provide greater equity, we allow the discrete-time quantum walk to also take multiple walk steps per oracle query while only counting queries. Then it matches the continuous-time algorithm's runtime, but such that it is a cubic speedup over its corresponding classical random walk. This yields a greater-than-quadratic speedup for quantum search over its corresponding classical random walk.

  16. What Can Learn from PER: Physics Education Research?

    CERN Document Server

    Singh, Chandralekha

    2016-01-01

    I believe that most teachers develop a belief in a set of pedagogical practices. As we teach, we try different ways to teach topics and then judge how successful the methods were. After several years, we have a compilation of techniques in our teaching toolbox. New teachers are at a disadvantage because they have fewer prior experiences to draw upon. Luckily, there is a group of physicists and physics educators who are researching how students learn physics, and have been able to show evidence of effective education practices in physics. They field of study is called PER: Physics Education Research. I asked Chandralekha Singh, one of the leaders in PER, to summarize some of the most relevant PER findings and her response follows.

  17. 13 bits per incident photon optical communications demonstration

    Science.gov (United States)

    Farr, William H.; Choi, John M.; Moision, Bruce

    2013-03-01

    Minimizing the mass and power burden of a laser transceiver on a spacecraft for interplanetary optical communications links drives requires operation in a "photon starved" regime. The relevant performance metric in the photon starved regime is Photon Information Efficiency (PIE) with units of bits per photon. Measuring this performance at the detector plane of an optical communications receiver, prior art has achieved performance levels around one bit per incident photon using pulse position modulation (PPM). By combining a PPM modulator with greater than 75 dB extinction ratio with a tungsten silicide (WSi) superconducting nanowire detector with greater than 83% detection efficiency we have demonstrated an optical communications link at 13 bits per incident photon.

  18. Empirical estimation of per capita brandy demand in Armenia

    Directory of Open Access Journals (Sweden)

    S.A. Movsisyan

    2017-03-01

    Full Text Available The empirical estimations were based on linear and double-log regression models, which identified the factors influencing the average per capita brandy demand in Armenia. The model was estimated using quarterly time-series data on per capita brandy consumption, disposable income, prices of various alcoholic beverages for 1997–2015 periods. This is quantitative study based on secondary annual, quarterly and monthly data, and 5% significance level. The average annual per capita brandy consumption data for 1997–2007 periods was obtained from WHO's website, whereas the 2008–2015 data was extracted from the National Statistical Service of the Republic of Armenia. For annual, quarterly and monthly periods from 1997 through 2015, the price data related to various alcoholic beverages, consumer price index were provided in NSS statistical publications of “Socio-Economic Situation of RA”, ”Consumer price indexes (prices in the Republic of Armenia”, “Prices and tariffs in the Republic of Armenia”. For 1997–2015 periods, the average monthly per capita monetary income data was obtained from “Living Standards of Population and Social Sphere” section of statistical yearbooks. The latter substituted the average per capita monthly disposable income data, since these data were unavailable. Meantime, since the data included numerous years, therefore, the nominal price and income data were adjusted for inflation using consumer price index with 2005 as base year. In conclusion, the average real prices of wine and vodka were statistically significant determinants of the average per capita brandy demand in Armenia, and the demand for brandy was inelastic.

  19. Analysing malaria drug trials on a per-individual or per-clone basis: a comparison of methods.

    Science.gov (United States)

    Jaki, Thomas; Parry, Alice; Winter, Katherine; Hastings, Ian

    2013-07-30

    There are a variety of methods used to estimate the effectiveness of antimalarial drugs in clinical trials, invariably on a per-person basis. A person, however, may have more than one malaria infection present at the time of treatment. We evaluate currently used methods for analysing malaria trials on a per-individual basis and introduce a novel method to estimate the cure rate on a per-infection (clone) basis. We used simulated and real data to highlight the differences of the various methods. We give special attention to classifying outcomes as cured, recrudescent (infections that never fully cleared) or ambiguous on the basis of genetic markers at three loci. To estimate cure rates on a per-clone basis, we used the genetic information within an individual before treatment to determine the number of clones present. We used the genetic information obtained at the time of treatment failure to classify clones as recrudescence or new infections. On the per-individual level, we find that the most accurate methods of classification label an individual as newly infected if all alleles are different at the beginning and at the time of failure and as a recrudescence if all or some alleles were the same. The most appropriate analysis method is survival analysis or alternatively for complete data/per-protocol analysis a proportion estimate that treats new infections as successes. We show that the analysis of drug effectiveness on a per-clone basis estimates the cure rate accurately and allows more detailed evaluation of the performance of the treatment. Copyright © 2012 John Wiley & Sons, Ltd.

  20. Planificación Municipal en el Perú

    OpenAIRE

    Hurtado Villanueva, Abelardo

    2013-01-01

    El presente trabajo tiene como finalidad explicar el nivel de planificación local y municipal en el Perú, para ello se procedió a interpretar los resultados alcanzados en cuanto al Plan de desarrollo local concertado y el Plan operativo institucional por la municipalidades del Perú al año 2011, y con ayuda de teorías científicas se puede establecer sus implicancias y repercusiones en el desempeño municipal, el desarrollo local y desarrollo humano. Se concluye que existe bajo nivel de plani...

  1. Restaural, sistema de gestió de comandes per restaurants

    OpenAIRE

    Solà Fernández, Xavier

    2006-01-01

    El projecte consisteix en un sistema informatitzat per restaurants centralitzat en un servidor que permet recollir comandes als clients a través de PDA’s i de pantalles tàctils situades a la barra per enviar-les als corresponents llocs d’ elaboració: -Terminal de la cuina on s’elaboraran tots els menjars. -Terminal de la bodega on es serviran els vins i caves. -Terminal barra on es serviran els licors, refrescos (entre d’altres productes totalment configurables). -Termina...

  2. Generació de codi C amb Matlab per DSP's

    OpenAIRE

    Gavaldà Bernal, Jordi

    2007-01-01

    Amb aquest projecte es pretén demostrar la generació automàtica de codis C a partir d’algoritmes desenvolupats amb Matlab i les seves llibreries per poder executar-los sobre una plataforma amb DSP de Texas Instruments (DSK 6711). Això inclou un estudi i realització de la comunicació Matlab-CCS-DSP per poder controlar l’algoritme que s’executa a la DSP mitjançant comunicació RTDX. En primer lloc s'explica l'entorn de treball del CCS i la comunicació de l'ordinador amb la t...

  3. Neutronics design and radiological aspects of HiPER facilities

    OpenAIRE

    Juarez Mañas, Rafael

    2013-01-01

    En este trabajo se han cubierto diferentes asuntos del diseño neutrónico de los aspectos radiológicos de las dos instalaciones del proyecto HiPER. El proyecto HiPER es un proyecto europeo concebido en el marco del programa ESFRI (European Scientific Facilities Research Infrastructure). Está destinado al desarrollo de la energía de fusión nuclear inercial mediante el uso de láseres y el esquema iluminación directa. Consecuentemente, se trata de una instalación con fines exclusivamente civiles....

  4. Adjetivos modificados con per- y prae- en Tácito

    Directory of Open Access Journals (Sweden)

    Joaquín Villalba Álvarez

    1998-06-01

    Full Text Available Throughout Latinity it is a common opinion the intensive force of some preverbs like per- or prae-, when they form modified adjectives (seuerus-perseuerus. This paper tries to analyse such type of adjectives in the works of Tacitus. After explaining the origin of these formations (seemingly proceeding from the sermo plebeius, and their different phases of creation in Latin literature, we review aH the forms found in Tacitus (eight with per- and seventeen with prae-, in order to examine their superlative force, their uis intentiua.

  5. Studio di Architetture e Protocolli per Reti Ottiche

    CERN Document Server

    Cucchi, R; Raffaelli, C; Vistoli, C

    1999-01-01

    Le reti ottiche basate sulla tecnologia WDM (Wavelength Division Multiplexing) sono molto promettenti per rispondere non solo alle esigenze di capacit trasmissiva ma anche per la realizzazione di reti costituite da apparati $9 esclusivamente ottici dove la lunghezza d¹onda rappresenta il circuito di comunicazione fra nodo sorgente e nodo destinatario.Questo documento prende in esame il ³trigger di II livello dell¹esperimento ATLAS come case study², ne $9 analizza le esigenze di trasmissione dei dati e descrive uno studio di fattibilit basato su una rete ottica a stella.

  6. Il progetto SISTER per il comune di Lignano Sabbiadoro

    OpenAIRE

    Alberto Poli

    2005-01-01

    Il comune di Lignano è stato recentemente invitato a Roma in qualità di relatore alla conferenza nazionale dei sistemi informativi territoriali organizzata da Esri, il maggior produttore mondiale di software per la gestione delle cartografie informatizzate. In tale occasione l’assessore AngeloBonelli ha presentato il progetto sperimentale di sistema informatico per la gestione del territorio, che è in corso da circa un anno. Ecco la sintesi della relazione del Sistema Informativo Integrato Te...

  7. Il progetto SISTER per il comune di Lignano Sabbiadoro

    Directory of Open Access Journals (Sweden)

    Alberto Poli

    2005-10-01

    Full Text Available Il comune di Lignano è stato recentemente invitato a Roma in qualità di relatore alla conferenza nazionale dei sistemi informativi territoriali organizzata da Esri, il maggior produttore mondiale di software per la gestione delle cartografie informatizzate. In tale occasione l’assessore AngeloBonelli ha presentato il progetto sperimentale di sistema informatico per la gestione del territorio, che è in corso da circa un anno. Ecco la sintesi della relazione del Sistema Informativo Integrato Territoriale (SISTER realizzato da Politecnica.

  8. Acantocéfalos del Perú

    OpenAIRE

    Tantaleán, Manuel; Unidad de Postgrado, Facultad de Ciencias Biológicas, Universidad Nacional Mayor de San Marcos; Sánchez, Lidia; Departamento de Protozoología, Helmintología e Invertebrados Afines. Museo de Historia Natural; Gómez, Luis; Departamento de Protozoología, Helmintología e Invertebrados Afines. Museo de Historia Natural; Huiza, Alina; Instituto de Medicina Tropical Daniel A. Carrión. UNMSM

    2013-01-01

    In this paper, the fullest information available about the Acanthocephalan discovered in Peru is presented, but also new hosts. En este trabajo, se reúne la mayor información disponible acerca de los acantocéfalos encontrados en el Perú y se incluyen nuevos huéspedes

  9. The demand for Kerosene and per capita income in Ethiopia ...

    African Journals Online (AJOL)

    We will also compare and contrast nominal prices and the amount of energy per unit cost for important fuels. Even though fuel wood has the lowest quality, it is the cheapest energy source among household fuels and that is why poor households preferred to consume it. Kerosene becomes the most expensive fuel than ...

  10. determinants of residential per capita water demand of makurdi ...

    African Journals Online (AJOL)

    This report presents the findings of the study on the determinants of residential per capita water demand of Makurdi metropolis in Benue State, Nigeria. Data for the study was obtained by the use of questionnaires, oral interviews and observations. The data was analyzed using SPSS. Twenty variables were considered in ...

  11. determinants of residential per capita water demand of makurdi

    African Journals Online (AJOL)

    user

    This report presents the findings of the study on the determinants of residential per capita water demand of. Makurdi metropolis in Benue State, Nigeria. Data for the study was obtained by the use of questionnaires, oral interviews and observations. The data was analyzed using SPSS. Twenty variables were considered in ...

  12. Genomic DNA extraction method from Annona senegalensis Pers ...

    African Journals Online (AJOL)

    aghomotsegin

    2014-02-05

    Feb 5, 2014 ... DNA fruit. 4 μl DNA was loaded per lane. (b) Restriction enzymes digestion of Annona senegalensis genomic. DNA. Lanes 1-3: DNA digested with Sau3A. Figure 2. Amplification of purified DNA with SSR-PCR. DNA was purified using the method described. The purified DNA was amplified using SSR-.

  13. Dynamic maintenance of majority information in constant time per update

    DEFF Research Database (Denmark)

    Frandsen, Gudmund Skovbjerg; Skyum, Sven

    1997-01-01

    We show how to maintain information about the existence of a majority colour in a set of elements under insertion and deletion of single elements using O(1) time and at most 4 equality tests on colours per update. No ordering information is used....

  14. Vreemd vermogen per land- en tuibouwbedrijf sterk toegenomen

    NARCIS (Netherlands)

    Meulen, van der H.A.B.

    2008-01-01

    Het vreemde vermogen op agrarische bedrijven is tussen 2002 en 2007 met 33% gestegen tot bijna 550.000 euro per bedrijf. Gemiddeld genomen wordt ongeveer een derde van het balanstotaal gefinancierd met vermogen verstrekt door derden. De glastuinbouwbedrijven hebben met gemiddeld circa 1 miljoen euro

  15. La (incumplida) promesa universitaria en el Perú

    OpenAIRE

    Cuenca, Ricardo; Reátegui, Luciana

    2016-01-01

    “El objetivo de este informe es mostrar qué sucedió con aquellas hipótesis de mediados de los años noventa mediante el análisis descriptivo de un conjunto de datos oficiales sobre la educación superior universitaria en el Perú.”—Introducción.

  16. Effect of different nematicide applications per year on banana ...

    African Journals Online (AJOL)

    Objective: The objective of this study was to evaluate the effect of different nematicide applications per year on control of banana root nematode, root weight and crop yield in Belize. The relationship between cost and benefit of the nematicide applications was also estimated. Methodology and results: A field experiment was ...

  17. Estimating Leaf Area Per Plant in Bambara Groundnut ( Vigna ...

    African Journals Online (AJOL)

    Equations relating leaf area to leaf dry weight and leaf number were developed for two local landraces of bambara groundnut (Vigna subterranean) grown in a greenhouse and in the field during the 1998/99 cropping season in Swaziland. During the seed filling stage the number of leaves on 10 plants per landrace were ...

  18. How Large Are the Cuts in Operating Grants per Student?

    Science.gov (United States)

    Burke, Gerald

    2008-01-01

    The 1988-89 Budget provides more detail on the Commonwealth's intentions for higher education as outlined in the Green and White Papers. This article focuses on one consequence of the Budget: the decline in operating grants per student in the period 1989 to 1991. Not all the data on expenditure and enrolments necessary for precise estimates are…

  19. Therapeutic Effects of Annona senegalensis Pers Stem Bark ...

    African Journals Online (AJOL)

    Therapeutic Effects of Annona senegalensis Pers Stem Bark Extracts in Experimental African Trypanosomiasis. ... International Journal of Health Research ... Results: Hexane extract, at a dose of 400 mg/kg body weight and aqueous extract at a dose of 300 mg/kg body weight, cured the experimental infection in mice.

  20. Measuring the nursing workload per shift in the ICU

    NARCIS (Netherlands)

    Debergh, Dieter P.; Myny, Dries; Van Herzeele, Isabelle; Van Maele, Georges; Miranda, Dinis Reis; Colardyn, Francis

    In the intensive care unit (ICU) different strategies and workload measurement tools exist to indicate the number of nurses needed. The gathered information is always focused on manpower needed per 24 h. However, a day consists of several shifts, which may be unequal in nursing workload. The aim of

  1. Thevetia neriifolia Juss. ex Steud Syn. J. peruviava (Pers.) Schum ...

    Indian Academy of Sciences (India)

    Thevetia neriifolia Juss. ex Steud Syn. J. peruviava (Pers.) Schum (English: yellow oleander; Hindi: Pili-. Kaner) of Apocynaceae is a small evergreen ornamental tree with strap-like simple leaves and funnel- shaped yellow flowers. Fruit is large with a single hard-shelled seed. Thevetia trees are largely cultivated in gardens ...

  2. Calculation of growth per cycle (GPC) of atomic layer deposited ...

    Indian Academy of Sciences (India)

    2014-03-06

    Mar 6, 2014 ... Calculation of growth per cycle (GPC) of atomic layer deposited aluminium oxide nanolayers and dependence of GPC on surface OH concentration. ANU PHILIP, SUBIN THOMAS and K RAJEEV KUMAR*. Department of Instrumentation, Cochin University of Science and Technology,. Cochin 682 022, India.

  3. Calculation of growth per cycle (GPC) of atomic layer deposited ...

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 82; Issue 3. Calculation of growth per cycle (GPC) of atomic layer deposited aluminium oxide nanolayers and dependence of GPC on surface OH concentration. Anu Philip Subin Thomas K Rajeev Kumar. Research Articles Volume 82 Issue 3 March 2014 pp 563-569 ...

  4. Economics of the one laptop per child in India

    NARCIS (Netherlands)

    James, M.J.

    2014-01-01

    Much controversy has surrounded the adoption of the one laptop per child (OLPC) programme in India. In the debate, however, an economics perspective has rarely been adopted. In what follows, accordingly, I use some basic economic principles to analyse the full-scale adoption of OLPC laptops in all

  5. Reply to Battro on the one laptop per child

    NARCIS (Netherlands)

    James, M.J.

    2013-01-01

    Dr. Battro takes issue with my paper on the One-Laptop-per-Child Programme that appeared in a 2010 issue of this journal (20/3). He raises a variety of issues that are relevant to this Programme but nowhere does he deal with my main point, namely, that poor countries simply cannot afford to give

  6. Macroeconomic consequences of the one laptop per child project

    NARCIS (Netherlands)

    James, M.J.

    Because some developing countries have adopted the One Laptop per Child (OLPC) project at the national level and others are planning to do so, the macroimplications of this idea can no longer be ignored. Accordingly, I examine whether or not full adoption of OLPC computers in primary schools

  7. Strategie robotiche ed informatiche per la fruizione museale

    National Research Council Canada - National Science Library

    Michela Cigola; Arturo Gallozzi; Marco Ceccarelli; Giuseppe Carbone; Claudio De Stefano; Alessandra Scotto di Freca

    2014-01-01

    ... sull’uso di robot per effettuare una visita ad un museo durante l’orario di chiusura, permettendo al visitatore, connesso al robot attraverso il proprio computer di casa o il proprio tablet o smartphone, di controllare e “guidare...

  8. Clinical and Parasitological Effects of Aspilia africana (Pers.)

    African Journals Online (AJOL)

    Department of Pharmacy, Makerere University

    This paper reports the findings of a clinical study of a herbal preparation of Aspilia africana (Pers.) C.D. Adams against malaria, corroborated by in vitro antiplasmodial and cytotoxicity tests. In a non-controlled prospective design, 15 patients with uncomplicated malaria were administered with the herbal preparation and ...

  9. What Can We Learn from PER: Physics Education Research?

    Science.gov (United States)

    Singh, Chandralekha

    2014-01-01

    Physics Education Research (PER) focuses on understanding how students learn physics at all levels and developing strategies to help students with diverse prior preparations learn physics more effectively. New physics instructors are encouraged to visit http://PhysPort.org, a website devoted to helping instructors find effective teaching resources…

  10. Genetic diversity of Annona senegalensis Pers. populations as ...

    African Journals Online (AJOL)

    Annona senegalensis Pers. is one of the wild fruit tree for domestication in southern Africa. An assessment of the genetic diversity in A. senegalensis would assist in planning for future germplasm collection, conservation and fruit domestication programmes. During 2004 to 2006 nine populations were collected from different ...

  11. 49 CFR 37.93 - One car per train rule.

    Science.gov (United States)

    2010-10-01

    ... light or rapid rail service shall ensure that each train, consisting of two or more vehicles, includes... 49 Transportation 1 2010-10-01 2010-10-01 false One car per train rule. 37.93 Section 37.93 Transportation Office of the Secretary of Transportation TRANSPORTATION SERVICES FOR INDIVIDUALS WITH...

  12. Per operative discovery of Placenta Praevia Percreta: A case report ...

    African Journals Online (AJOL)

    Placenta percreta is a rare pathological entity with challenging diagnostic and therapeutic requirements especially for resource limited settings. We present here the case of a 40 year old woman with a per operative diagnosis of placenta accreta during a caesarian section indicated for placenta praevia. We highlight the ...

  13. Lista dei caratteri macroscopici per l’identificazione dei legni

    Science.gov (United States)

    Flavio Ruffinatto; Alan Crivellaro; Alex C. Wiedenhoeft

    2016-01-01

    L’identificazione dei legni costituisce il primo passo per ottenere conoscenze indispensabili in molti ambiti di studio. Ad esempio, prima di eseguire il restauro di un manufatto di interesse culturale è indispensabile conoscere il nome dei legni che lo compongono. Oppure, nel caso in cui si sospetti che un legno protetto da convenzioni internazionali sia stato...

  14. Il progetto SISTER per il comune di Lignano Sabbiadoro

    Directory of Open Access Journals (Sweden)

    Alberto Poli

    2005-10-01

    Bonelli ha presentato il progetto sperimentale di sistema informatico per la gestione del territorio, che è in corso da circa un anno. Ecco la sintesi della relazione del Sistema Informativo Integrato Territoriale (SISTER realizzato da Politecnica.

  15. Modello metodologico per il monitoraggio degli incidenti stradali in Trentino

    Directory of Open Access Journals (Sweden)

    P. Fateh-Moghadam

    2003-05-01

    Full Text Available

    Obiettivi: realizzazione di un’infrastruttura informatica, per l’unificazione tempestiva dei flussi sugli incidenti stradali (ISTAT-ACI e sanitari con la georeferenziazione degli eventi a partire dall’anno 2000.

    Materiali e Metodi: dall’archivio di Trentino emergenza sono stati estratti gli interventi per incidente stradale selezionando la combinazione: descrizione patologica: “traumatismi”, tipologia luogo: “strada”, tipologia incidente. Dai dati di ogni Pronto soccorso è stato costruito un archivio unico contenente il totale degli accessi e sono stati estratti gli accessi per “incidente stradale” e quelli per lesioni accidentali in generale. Dall’archivio SDO si sono selezionati sia i ricoveri con il criterio “3” alla variabile mtraav (=incidente stradale che quelli per traumatismi.

    Nell’ambito del progetto “Metodi informatici predittivi per la mitigazione del rischio da incidenti stradali” (Mitris, finanziato dal Ministero della Salute, è stata realizzata l’immissione tramite interfaccia internet o decodifica automatica dei verbali informatizzati delle Forze dell’ordine, e la contestuale realizzazione di un interfaccia WebGIS
    in grado di visualizzare la localizzazione degli incidenti stradali.

    Risultati: tramite la combinazione “data nascita”,
    “data incidente”, “sesso” è stato eseguito un primo collegamento tra gli archivi. Aggiungendo alla data incidente uno o più giorni, è stato costruito un nuovo archivio PS contenente il 97,4% degli eventi raccolti dalle forze dell’Ordine e contenuti nel data base Mitris. Approccio analogo è stato seguito per il linkage con SDO e 118. Tramite interfaccia WebGIS è stata creata una mappa degli incidenti interrogabile on-line, che oltre alla semplice localizzazione riporta dinamica e esiti con possibilità di produrre statistiche e grafici. Il sistema copre attualmente

  16. The Application of SNiPER to the JUNO Simulation

    Science.gov (United States)

    Lin, Tao; Zou, Jiaheng; Li, Weidong; Deng, Ziyan; Fang, Xiao; Cao, Guofu; Huang, Xingtao; You, Zhengyun; JUNO Collaboration

    2017-10-01

    The JUNO (Jiangmen Underground Neutrino Observatory) is a multipurpose neutrino experiment which is designed to determine neutrino mass hierarchy and precisely measure oscillation parameters. As one of the important systems, the JUNO offline software is being developed using the SNiPER software. In this proceeding, we focus on the requirements of JUNO simulation and present the working solution based on the SNiPER. The JUNO simulation framework is in charge of managing event data, detector geometries and materials, physics processes, simulation truth information etc. It glues physics generator, detector simulation and electronics simulation modules together to achieve a full simulation chain. In the implementation of the framework, many attractive characteristics of the SNiPER have been used, such as dynamic loading, flexible flow control, multiple event management and Python binding. Furthermore, additional efforts have been made to make both detector and electronics simulation flexible enough to accommodate and optimize different detector designs. For the Geant4-based detector simulation, each sub-detector component is implemented as a SNiPER tool which is a dynamically loadable and configurable plugin. So it is possible to select the detector configuration at runtime. The framework provides the event loop to drive the detector simulation and interacts with the Geant4 which is implemented as a passive service. All levels of user actions are wrapped into different customizable tools, so that user functions can be easily extended by just adding new tools. The electronics simulation has been implemented by following an event driven scheme. The SNiPER task component is used to simulate data processing steps in the electronics modules. The electronics and trigger are synchronized by triggered events containing possible physics signals. The JUNO simulation software has been released and is being used by the JUNO collaboration to do detector design optimization, event

  17. Disseny de les pautes per la redacció del protocol de gestió per les aus del PNAE

    OpenAIRE

    Merino Fajarnés, Eladio; Murlà Tuyls, Damián; Pérez Martínez, Sònia; Soley Prieto, Susanna

    2006-01-01

    Aquest projecte té com a objectius: determinar les Directrius a seguir per la futura redacció d’un protocol de gestió de les zones inundables del PNAE, amb la finalitat de potenciar la presència d’aus; determinar les millors condicions d’hàbitat per les poblacions d’aus del PNAE i redactar unes línies de seguiment que permetin d'una banda avaluar si les pautes proposades tindran l’efecte desitjat i d'altra banda que permetin la redacció del protocol de gestió

  18. Rapid spectroscopic determination of per cent aromatics, per cent saturates and freezing point of JP-4 aviation fuel

    Energy Technology Data Exchange (ETDEWEB)

    Lysaght, M.J.; Kelly, J.J.; Callis, J.B. (Washington University, Seattle, WA (USA). Dept. of Chemistry)

    1993-05-01

    Near-infrared (n.i.r.) spectroscopy in both the short wavelength region (700-1100 nm) and the long wavelength region (1100-1500 nm) is evaluated as a rapid method for the simultaneous estimation of the freezing point and volume percentages of aromatics and saturates of aviation fuels. Thirty-three JP-4 samples were independently analysed by six industrial and government laboratories for freezing point and for volume per cent aromatics and volume per cent saturates by fluorescent indicator adsorption. These results were then used to calibrate the sample's n.i.r. spectra. Both multiple linear regression and partial least squares calibration methods were evaluated and gave comparable performance. The n.i.r. spectral analysis predictions for these properties were within the standard deviations of the round-robin values. Specially, the per cent aromatics and per cent saturates were within 1% and the freezing point within 2.5[degree]C of the laboratory-determined values. N.i.r. spectroscopy appears to have considerable promise as a rapid non-destructive method for jet fuel analysis. 27 refs., 8 figs., 6 tabs.

  19. SCN-AVP release of mPer1/mPer2 double-mutant mice in vitro

    Directory of Open Access Journals (Sweden)

    Oster Henrik

    2008-03-01

    Full Text Available Abstract Background Circadian organisation of behavioural and physiological rhythms in mammals is largely driven by the clock in the suprachiasmatic nuclei (SCN of the hypothalamus. In this clock, a molecular transcriptional repression and activation mechanism generates near 24 hour rhythms. One of the outputs of the molecular clock in specific SCN neurons is arginine-vasopressin (AVP, which is responsive to transcriptional activation by clock gene products. As negative regulators, the protein products of the period genes are thought to repress transcriptional activity of the positive limb after heterodimerisation with CRYPTOCHROME. When both the Per1 and Per2 genes are dysfunctional by targeted deletion of the PAS heterodimer binding domain, mice lose circadian organization of behaviour upon release into constant environmental conditions. To which degree the period genes are involved in the control of AVP output is unknown. Methods Using an in vitro slice culture setup, SCN-AVP release of cultures made of 10 wildtype and 9 Per1/2 double-mutant mice was assayed. Mice were sacrificed in either the early light phase of the light-dark cycle, or in the early subjective day on the first day of constant dark. Results Here we report that in arrhythmic homozygous Per1/2 double-mutant mice there is still a diurnal peak in in vitro AVP release from the SCN similar to that of wildtypes but distinctively different from the release pattern from the paraventricular nucleus. Such a modulation of AVP release is unexpected in mice where the circadian clockwork is thought to be disrupted. Conclusion Our results suggest that the circadian clock in these animals, although deficient in (most behavioural and molecular rhythms, may still be (partially functional, possibly as an hourglass mechanism. The level of perturbation of the clock in Per1/2 double mutants may therefore be less than was originally thought.

  20. Capsule endoscopy capture rate: Has 4 frames-per-second any impact over 2 frames-per-second?

    Science.gov (United States)

    Fernandez-Urien, Ignacio; Carretero, Cristina; Borobio, Erika; Borda, Ana; Estevez, Emilio; Galter, Sara; Gonzalez-Suarez, Begoña; Gonzalez, Benito; Lujan, Marisol; Martinez, Jose Luis; Martínez, Vanessa; Menchén, Pedro; Navajas, Javier; Pons, Vicente; Prieto, Cesar; Valle, Julio

    2014-01-01

    AIM: To compare the current capsule and a new prototype at 2 and 4 frames-per-second, respectively, in terms of clinical and therapeutic impact. METHODS: One hundred patients with an indication for capsule endoscopy were included in the study. All procedures were performed with the new device (SB24). After an exhaustive evaluation of the SB24 videos, they were then converted to “SB2-like” videos for their evaluation. Findings, frames per finding, and clinical and therapeutic impact derived from video visualization were analyzed. Kappa index for interobserver agreement and χ2 and Student’s t tests for qualitative/quantitative variables, respectively, were used. Values of P under 0.05 were considered statistically significant. RESULTS: Eighty-nine out of 100 cases included in the study were ultimately included in the analysis. The SB24 videos detected the anatomical landmarks (Z-line and duodenal papilla) and lesions in more patients than the “SB2-like” videos. On the other hand, the SB24 videos detected more frames per landmark/lesion than the “SB2-like” videos. However, these differences were not statistically significant (P > 0.05). Both clinical and therapeutic impacts were similar between SB24 and “SB2-like” videos (K = 0.954). The time spent by readers was significantly higher for SB24 videos visualization (P videos when all images captured by the capsule were considered. However, these differences become non-significant if we only take into account small bowel images (P > 0.05). CONCLUSION: More frames-per-second detect more landmarks, lesions, and frames per landmark/lesion, but is time consuming and has a very low impact on clinical and therapeutic management. PMID:25339834

  1. BASI ANTISISMICHE IN MARMO PER I BRONZI DI RIACE

    Directory of Open Access Journals (Sweden)

    Gerardo De Canio

    2012-04-01

    Full Text Available

    Nell'ambito di una convenzione stipulata con la Direzione Regionale per i BeniCulturali e Paesaggistici della Calabria, l’ENEA ha progettato e realizzato innovative basi antisismiche in marmo per i Bronzi di Riace in procinto di essere collocati in una nuova sede espositiva del Museo Archeologico Nazionale della Magna Grecia a Reggio Calabria.

     

    Earthquake-resistant marble bases

    ENEA has designed and implemented innovative earthquake-resistant marble bases for Bronze Statues, which will be placed in a new venue of the National Archaeological Museum of Magna Greece in Reggio Calabria.

  2. Trombose da veia renal no período neonatal

    OpenAIRE

    Morais, Sofia; Santos, Raquel; Gomes, Clara; Correia, António Jorge

    2014-01-01

    Introdução: A trombose da veia renal (TVR) no período neonatal é uma entidade rara. As complicações a longo prazo incluem hipertensão arterial, atrofia renal e insuficiência renal crónica. Objectivo: Revisão da abordagem das atitudes na fase aguda e evolução a longo prazo das crianças com TVR neonatal seguidas numa consulta de Nefrologia Pediátrica. Material e métodos: Análise retrospectiva dos processos das crianças com antecedentes de TVR no período neonatal. Foram avaliados os factores de ...

  3. Aportes del Proyecto de Educación Rural (PER)

    OpenAIRE

    Cubillo Jiménez, Kenneth Alfredo; Chaves Murillo, Urania María

    2011-01-01

    Recibido 05 de mayo de 2010 • Aceptado 31 de agosto de 2010 • Corregido 27 de julio de 2011 El presente artículo se deriva de la investigación “El proceso de formación inicial del Proyecto de Educación Rural (PER)”, desarrollada entre 1984 y 1987 en las Direcciones Regionales de Educación de San Carlos, Coto y Limón, y sus aportes para los procesos formativos en la actualidad. El PER fue implementado por el Centro de Investigación en Docencia y Educación (CIDE), de la Universidad Nacional (UN...

  4. Gentianaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Susy Castillo

    2013-10-01

    Full Text Available La familia Gentianaceae es reconocida en el Perú por presentar alrededor de 15 géneros y aproximadamente de 170 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004; S. Castillo, com.pers., mayormente hierbas y arbustos. En este trabajo se reconoce 103 especies endémicas en siete géneros. Los géneros con mayor número de especies endemicas son Gentianella y Macrocarpaea. Las especies endémicas ocupan principalmente las regiones de la Puna Húmeda y Seca, Páramo y Bosque Muy Húmedo Montano, entre los 1000 y 5100 m de altitud. Se aplicaron las categorías y criterios de la UICN a 99 especies. Treinta y tres especies endémicas se encuentran representadas dentro de un área protegida.

  5. Apiaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Apiaceae es reconocida en el Perú por presentar 29 géneros y 88 especies (Brako & Zarucchi, 1993, básicamente hierbas y subarbustos. En este trabajo reconocemos como endémicos 22 taxones en siete géneros. Un género, Paraselinum, es endémico del Perú. La mayoría de los taxones endémicos ocupan las regiones Desierto Semicálido Costero, Mesoandina y Bosques Muy Húmedos Montanos, entre los 10 y 4400 m de altitud. Ninguna de estas especies está representada en las áreas protegidas.

  6. Per and polyfluorinated substances in the Nordic Countries

    DEFF Research Database (Denmark)

    Posner, Stefan; Roos, Sandra; Brunn Poulsen, Pia

    This Tema Nord report presents a study based on open information and custom market research to review the most common perfluorinated substances (PFC) with less focus on PFOS and PFOA. The study includes three major parts: 1) Identification of relevant per-and polyfluorinated substances and their ......This Tema Nord report presents a study based on open information and custom market research to review the most common perfluorinated substances (PFC) with less focus on PFOS and PFOA. The study includes three major parts: 1) Identification of relevant per-and polyfluorinated substances...... prioritized in 2) There is a lack of physical chemical data, analystical reference substances, human and environmental occurrence and toxicology data, as well as market information regarding PFCs other than PFOA and PFOS and the current legislation cannot enforce disclosure of specific PFC substance...

  7. Immagini dinamiche: appunti per un catalogo degli usi didattici

    Directory of Open Access Journals (Sweden)

    Filippo Bruni

    2013-03-01

    Full Text Available Le immagini dinamiche costituiscono un’importante risorsa per le attività didattiche. A partire da una riflessione storica, si evidenzia in primo luogo l’importanza di un loro uso efficace alla luce della classificazione operata da Clark e Lyons. In secondo luogo si segnalano alcune attività emergenti legate alla documentazione, al digital storytelling e alla formazione degli insegnanti.

  8. Capabilities for per Process Tuning of Distributed Operating Systems

    OpenAIRE

    Margery, David; Lottiaux, Renaud; Morin, Christine

    2004-01-01

    This paper introduces capabilities as a tool to tailor cluster mechanisms usage on a per process basis in a single system image operating system. Using capabilities, processes should only pay the cost in terms of OS resources for the operating system of the mechanisms they want to use. We relate capabilities to policies that are used to try to ensure optimal resource usage across all cluster nodes. Finally, we discuss implementation of these ideas in Kerrighed and describe its usage on a real...

  9. Quali politiche di innovazione tecnologica per la scuola italiana?

    Directory of Open Access Journals (Sweden)

    Licia Cianfriglia

    2013-12-01

    Full Text Available Il presente contributo affronta il tema del rapporto tra introduzione delle tecnologie in classe e cambiamenti delle pratiche degli insegnanti. Alla luce dei cambiamenti sociali e delle abitudini degli individui, sulla base della conoscenza diretta della realtà scolastica del Paese, e dei dati messi a disposizione dalle indagini nazionali e internazionali sui comportamenti professionali dei docenti e sulle competenze acquisite dagli alunni, intende evidenziare le scelte necessarie per attuare efficaci politiche di innovazione della scuola italiana.

  10. Regional differences in intelligence and per capita income in Portugal

    OpenAIRE

    Almeida,Leandro S.; Lemos, Gina C.; Lynn, Richard

    2011-01-01

    Regional differences in IQ and per capita incomes are presented for five regions of Portugal: North, North Central, Lisbon-Central, Lisbon-Suburb, and South. Regional IQs were calculated from a representative sample of 4548 Portuguese school students from 5th to 12th grades. The average IQ and average incomes are highest in Central Lisbon. The results show a positive association between IQs and average regional incomes, as it has been observed in other countries.

  11. CALiPER Exploratory Study. Recessed Troffer Lighting

    Energy Technology Data Exchange (ETDEWEB)

    Miller, N. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Royer, M. P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Poplawski, M. E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2013-03-01

    This CALiPER study examines the problems and benefits likely to be encountered with LED products intended to replace linear fluorescent lamps. LED dedicated troffers, replacement tubes, and non-tube retrofit kits were evaluated against fluorescent benchmark troffers in a simulated office space for photometric distribution, uniformity of light on the task surface, suitability of light output, flicker, dimming performance, color quality, power quality, safety and certification issues, ease of installation, energy efficiency, and life-cycle cost.

  12. A new 4-oxazolidinone from Sorghum halepense (L. Pers.

    Directory of Open Access Journals (Sweden)

    Hongjuan Huang

    2015-01-01

    Full Text Available Sorghum halepense (L. Pers. is known as invasive weed in the world . In this paper we report three rare natural products from this weed. The compounds include a new rare natural product 2,2-dimethyl-5-(4-hydroxyphenyl-4-oxazolidinone (1, and two other known mandelic acid derivatives, ethyl 4-hydroxymandelate (2 and 4-hydroxymandelamide (3. The structures of these compounds were elucidated by extensive spectroscopic analysis (MS, IR, 1H, 13C NMR and 2D NMR.

  13. La responsabilità delle imprese multinazionali per crimini internazionali

    OpenAIRE

    Ricci, Mena

    2015-01-01

    L’attività di ricerca nell'ambito del Dottorato di ricerca “Persone, imprese e lavoro: dal diritto interno a quello internazionale” ha consentito di studiare ed approfondire una tematica nuova del diritto internazionale, ossia “La responsabilità delle imprese multinazionali per crimini internazionali”. Il progetto di ricerca è stato strutturato su tre parti dedicate rispettivamente alla soggettività giuridica delle imprese multinazionali, ai diversi profili di responsabilità che possono e...

  14. Thesaurus: un sistema per la conoscenza del patrimonio sommerso

    Directory of Open Access Journals (Sweden)

    Denise La Monica

    2013-03-01

    Full Text Available ItIl progetto Thesaurus (TecnicHe per l’Esplorazione Sottomarina Archeologica mediante l’Utilizzo di Robot aUtonomi in Sciami affronta lo sviluppo di metodologie e tecnologie scientifiche multidisciplinari al fine di individuare, censire e documentare manufatti e relitti subacquei di interesse archeologico e storico. Il sistema di gestione e consultazione dei dati già realizzato, a partire da un’attenta analisi di altri sistemi informativi e progetti similari, contiene sia dati sensoriali ottenuti mediante tecnologie avanzate per l’esplorazione dei fondali, sia dati di natura storica, archeologica e documentaria derivanti dalle ricerche umanistiche.EnThe goal of the project Thesaurus (TecnicHe per l’Esplorazione Sottomarina Archeologica mediante l’Utilizzo di Robot aUtonomi in Sciami is to develop multidisciplinary technologies and scientific methodologies in the aim of pinpointing, conducting a census and documenting artifacts and underwater wrecks of archaeological or historical interest. After having considered other similar projects and information systems, we implemented a system for managing and retrieving data, where sensory data gathered through advanced technologies to explore sea bottom, as well as data acquired through historical, archaeological and documentary research, are stored.

  15. La riscoperta della stereoscopia per la rappresentazione dello spazio architettonico

    Directory of Open Access Journals (Sweden)

    Simone Garagnani

    2011-06-01

    Full Text Available Il progressivo sviluppo dei metodi della rappresentazione grafica nel corso della storia è stato possibile in virtù della scoperta di strumenti e tecniche appartenenti al loro tempo: questo continuo progresso delle modalità di “raccontare” l’architettura è tuttora in corso di evoluzione, costituendo il fondamento di ogni strategia informativa e di comunicazione del progetto. Il sempre più pervasivo trattamento digitale dell’informazione, sia essa grafica che testuale, ha condotto ad una progressiva riscoperta di approcci tradizionali nella descrizione dello spazio costruito, declinandoli alle nuove tecnologie informatiche per amplificarne possibilità e valenze. È il caso della stereoscopia, diffuso metodo ottocentesco adottato in fotografia per rendere spaziale la percezione dell’immagine sfruttando la visione binoculare; oggi i modelli tridimensionali e le immagini digitali catturate da apposite fotocamere rendono l’approccio stereoscopico di immediato utilizzo anche per i profani della rappresentazione, semplificando e rendendo trasparenti i concetti di geometria proiettiva alla base del metodo. Questo contributo intende indagare le funzionalità, i vantaggi e le criticità della tecnologia stereoscopica immersiva nella moderna comunicazione del progetto d’architettura.

  16. Per un dizionario della ricerca sul Technology Enhanced Learning

    Directory of Open Access Journals (Sweden)

    Nicolas Balacheff

    2012-12-01

    Full Text Available Questo articolo presenta le principali linee di azione di un meta-progetto iniziato nell’ambito della Rete di Eccellenza STELLAR con l’obiettivo di creare e dare struttura a un Thesaurus e a un Dizionario dei termini e delle espressioni in uso nell’ambito della ricerca sul Technology Enhanced Learning (TEL. Questo meta-progetto intende fornire gli strumenti per superare le difficoltà dovute alla ricchezza e alla rapida evoluzione di quest’area di ricerca multidisciplinare, allo scopo di facilitare il coinvolgimento dei ricercatori giovani e di quelli che si accostano per la prima volta a questo settore, nonché di tutti coloro che a vario titolo si interessano al TEL. Il meta-progetto in questione ha anche l’ambizione di facilitare la comunicazione tra individui appartenenti a diverse culture scientifiche e tra le lingue nazionali. Dopo una presentazione delle motivazioni, vengono discussi gli attuali sviluppi del lavoro e presentati i criteri seguiti per le principali scelte effettuate in merito ai metodi e alle tecnologie utilizzate.

  17. The need for drugged driving per se laws: a commentary.

    Science.gov (United States)

    DuPont, Robert L; Voas, Robert B; Walsh, J Michael; Shea, Corinne; Talpins, Stephen K; Neil, Mark M

    2012-01-01

    Triggered by the new federal commitment announced by the Office of National Drug Control Policy (ONCDP) to encourage states to enact drugged driving per se laws, this article reviews the reasons to establish such laws and the issues that may arise when trying to enforce them. A review of the state of drunk driving per se laws and their implications for drugged driving is presented, with a review of impaired driving enforcement procedures and drug testing technology. Currently, enforcement of drugged driving laws is an adjunct to the enforcement of laws regarding alcohol impairment. Drivers are apprehended when showing signs of alcohol intoxication and only in the relatively few cases where the blood alcohol concentration of the arrested driver does not account for the observed behavior is the possibility of drug impairment pursued. In most states, the term impaired driving covers both alcohol and drug impairment; thus, driver conviction records may not distinguish between the two different sources of impairment. As a result, enforcement statistics do not reflect the prevalence of drugged driving. Based on the analysis presented, this article recommends a number of steps that can be taken to evaluate current drugged driving enforcement procedures and to move toward the enactment of drug per se laws.

  18. Prevalencia de Esclerosis Múltiple en Lima - Perú

    Directory of Open Access Journals (Sweden)

    Darwin Vizcarra Escobar

    2009-07-01

    Full Text Available La Esclerosis Múltiple (EM es la principal enfermedad desmielinizante a nivel mundial. La epidemiología señala una mayor prevalencia de esta entidad en áreas alejadas de la línea ecuatorial. Existen algunos estudios de prevalencia en Latinoamérica, ninguno publicado en el Perú. Objetivo: Determinar la prevalencia de Esclerosis Múltiple en Lima, Perú. Material y métodos: Se utilizó el método captura recaptura para estimar la prevalencia de EM en Lima en 4 centros de pacientes con Esclerosis Múltiple de la ciudad: Hypnos Instituto del Sueño en la Clínica San Felipe, el Hospital Nacional Cayetano Heredia, la Clínica El Golf y la Asociación "Esclerosis Múltiple Perú" (ESMUP. Resultados: Se calculó la prevalencia de EM en 7,69 x 100 000 habitantes (intervalo de confianza al 95 % 7,09 a 8,30. Conclusiones: La prevalencia estimada de EM, para la ciudad de Lima, se encuentra en rango medio bajo. (Rev Med Hered 2009;20:146-150.

  19. Large Scale Structure in CHILES using DisPerSE

    Science.gov (United States)

    Luber, Nicholas Matthew; van Gorkom, Jacqueline; Hess, Kelley; Pisano, D. J.; Fernandez, Ximena; Momjian, Emmanuel

    2018-01-01

    We apply the Discrete Persistence Source Extractor (DisPerSE) to the distribution of galaxies in the COSMOS field and isolate the best parameters in DisPerSE for identifying filaments in the field. The identification of the cosmic web, and the ability of CHILES to study the resolved neutral hydrogen morphologies and kinematics of galaxies, will allow us to study the properties of neutral hydrogen in different cosmic web environments across the redshift range $z$ = 0.1 - 0.5. We identify the parameters in DisPerSE and create the methodology that provides for the best results given the relatively small field of view of the COSMOS field and the increasing incompleteness of the survey with increasing redshift. The catalog we use is compiled using high confidence spectroscopic redshifts from the GAMA G10 data release and photometry/ancillary data from COSMOS2015. We analyze two-dimensional slices, extract the filaments, and calculate the distance from each galaxy to the cosmic web in each slice. We present correlations between galaxy properties and cosmic web environments--namely, that redder and more massive galaxies are closer to filaments--and highlight the relationship between color and stellar mass. Additionally, we discuss the cold gas morphology of a few individual galaxies and their positions with respect to the cosmic web.

  20. Analisi dei processi di un ambulatorio per i viaggiatori internazionali

    Directory of Open Access Journals (Sweden)

    M.L. Demarchi

    2003-05-01

    Full Text Available

    Obiettivi: 1 determinare i costi di gestione dell’ambulatorio del viaggiatore internazionale dell’ASL13 di Novara; 2 predisporre un piano di riorganizzazione dell’ambulatorio. Materiali e metodi: per la determinazione dei costi di gestione dell’ambulatorio è stata applicata la metodologia dell’Activity Based Costing (ABC che consiste nello scomporre, secondo un criterio gerarchico, le attività che costituiscono un processo, partendo da quelle poste a livello più elevato (macroattività e giungendo al singolo compito professionale (microattività.

    In seguito per ogni attività individuata ciascun operatore del servizio indica, in percentuale, il tempo mediamente dedicato a tale attività, al fine di quantificarne il costo. Le attività individuate sono state rappresentate graficamente con la tecnica del Work design secondo cui per ciascun processo sono identificati input, output, risorse utilizzate, nonché eventuali regole e controlli a cui è soggetto.

    Risultati: lo studio ha coinvolto tutti gli operatori dell’ambulatorio (4 medici, 2 assistenti sanitari e 1 assistente amministrativo.

    Sono state identificate 180 attività. Il costo annuale complessivo della gestione dell’ambulatorio, attribuibile alle risorse umane, è pari a ¤ 288.934. Complessivamente il costo di alcune attività è risultato particolarmente elevato, in quanto le attività stesse vengono svolte da figure professionali non pertinenti (es. attività amministrative svolte dall’infermiere, attività di pertinenza infermieristica effettuate dal medico.
    Attraverso la definizione di input, output, controlli e meccanismi, è stato possibile evidenziare sia le macro criticità del processo organizzativo, quali ad esempio la necessità di integrare l’utilizzo di supporti informatizzati per la gestione delle informazioni relative all’utente, sia le micro criticità, come l’esigenza di predisporre

  1. KAJIAN MANAJEMEN PRODUKSI PEMBERITAAN PSO BIDANG PERS OLEH LKBN ANTARA

    Directory of Open Access Journals (Sweden)

    Primayanti Primayanti

    2015-05-01

    Full Text Available Based on Government Regulation No. 40 Year 2007 on Perum ANTARA do fund public services (public service obligation / PSO in the field of government information. ANTARA position is also very strategic in the middle of the fight-laden media industry interests. Also, the need to get in the news media with the retail product line strategy while maintaining the main products for the media.Results of this study showed that the press area of public service obligations (PSO-Field Press includes a number of products and services that news text, photo news, and TV news. In line with government policies and programs, also set a number of themes that frame the products and services fields PSO Press.PSO and Field Releases can be interpreted as the government's efforts to maintain control and domination of the media life, given the strategic function of political economy of media. A contradiction was born. On the one hand, the government wants to adopt the principles of the liberal press, on the other hand maintain government policies in the media sector as opposed to the spirit of libertarianism. Berdasarkan Peraturan Pemerintah Nomor 40 Tahun 2007 tentang Perum LKBN ANTARA dilakukan dana pelayanan umum (public service obligation/PSO di bidang informasi dari pemerintah. Posisi LKBN ANTARA juga sangat strategis di tengah pertarungan industri media yang sarat kepentingan. Juga, perlunya kantor berita masuk media ritel dengan strategi lini produk dengan tetap mempertahankan produk utama untuk media.Hasil penelitian ini menujukkan bahwa kewajiban pelayanan umum bidang pers (PSO-Bidang Pers tersebut mencakup sejumlah produk dan layanan yaitu berita teks, berita foto, dan berita TV. Agar sejalan dengan program dan kebijakan pemerintah, ditetapkan pula sejumlah tema yang membingkai produk dan layanan PSO Bidang Pers.PSO Bidang Pers dapat dimaknai sebagai upaya pemerintah yang ingin mempertahankan kontrol dan dominasinya terhadap kehidupan media, mengingat begitu

  2. LA FORMAZIONE DEGLI INSEGNANTI PER UNA EDUCAZIONE PLURILINGUE E INTERCULTURALE

    Directory of Open Access Journals (Sweden)

    Edoardo Lugarini

    2012-07-01

    Full Text Available Dalla la Guida per lo sviluppo e l’attuazione di curricoli per una educazione plurilingue e interculturale del Consiglio d’Europa è possibile trarre una serie di indicazioni per disegnare un profilo professionale e, di conseguenza, una serie di indicazioni per la formazione iniziale e in servizio dell’insegnate di lingua (L1, L2, LS. In questo intervento si suggeriscono, senza alcuna pretesa di esaustività, degli indicatori relativi alle competenze professionali che l’insegnante dovrebbe possedere per poter svolgere la sua attività nella scuola italiana di oggi in considerazione dei bisogni linguistici delle nuove generazioni e degli obiettivi linguistici proposti dal Consiglio d’Europa nell’ambito delle politiche educative orientate a favorire la mobilità, una più efficace comunicazione internazionale, il rispetto dell’identità e della diversità delle culture, a sviluppare l’educazione alla cittadinanza democratica ed europea. Dalle riflessioni condotte emerge la necessità di una formazione disciplinare e didattica articolata e complessa che renda l’insegnante “professionista riflessivo” e “ricercatore sperimentale”TRAINING TEACHERS FOR MULTILINGUISTIC, INTERCULTURAL EDUCATIONFrom the Council of Europe’s Guide for the development and implementation of curricula for multilingual and intercultural education, it is possible to draw a series of explicit or implicit characteristics for teachers, and consequently, a series of indications for initial and in-service language (L1, L2, FL teacher training. This paper offers a brief view of the professional competences teachers should possess in order to carry out their roles in Italian schools considering the linguistic needs of the young generations and the language objectives set out by the Council of Europe regarding education policies that promote mobility, more effective International communication and respect for cultural identity and diversity, in an effort to

  3. Reti per la mobilità e sicurezza

    Directory of Open Access Journals (Sweden)

    Adriana Galderisi

    2009-07-01

    Full Text Available Una riflessione centrale nell’ambito del rapporto mobilità e sicurezza è quella relativa al ruolo che le reti per la mobilità rivestono, o possono rivestire, nel garantire la sicurezza del territorio rispetto a fattori di rischio, naturali o antropici. Già da alcuni anni, accrescere la sicurezza delle comunità insediate ai rischi costituisce uno degli obiettivi prioritari delle strategie volte ad orientare in chiave di sostenibilità lo sviluppo urbano e territoriale. Le reti per la mobilità rivestono, in tale contesto, un ruolo centrale: essenziali supporti alla vita quotidiana delle comunità - da cui dipende in molti casi la salute, il comfort e, più in generale, il benessere socioeconomico - esse rappresentano, da un lato ,elementi esposti e spesso ad elevata vulnerabilità rispetto ai diversi fenomeni calamitosi; dall’altro, attrezzature di importanza strategica per la gestione dell’emergenza, indispensabili per garantire l’accesso e l’esodo dalle aree colpite nella fase dell’immediato post evento. Il danneggiamento o la ridotta funzionalità di tali reti può incrementare, anche significativamente, le perdite di vite umane conseguenti ad un evento calamitoso, oltreché indurre danni economici rilevanti anche su orizzonti temporali di medio-lungo periodo. Inoltre, ampliando il campo di attenzione dalle reti come supporti fisici ai flussi di persone e beni che esse supportano, gli impatti di un evento calamitoso su singoli elementi di tali reti possono indurre eventi secondari anche di grande rilevanza quali, ad esempio, rilasci tossici o esplosioni, dovute a danni sulla rete che coinvolgono mezzi per il trasporto di sostanze pericolose o serbatoi localizzati lungo la rete o all’interno dei nodi della rete di trasporto. Tuttavia, nonostante la riconosciuta centralità delle reti per la mobilità, nel garantire la sicurezza del territorio, le analisi di rischio sono state a lungo incentrate prevalentemente sui manufatti

  4. Tecniche integrate di rilievo per la comprensione di contesti archeologici e paesaggistici: note metodologiche per un approccio multi-scalare.

    Directory of Open Access Journals (Sweden)

    Mariangela Liuzzo

    2017-12-01

    Full Text Available L’obiettivo della ricerca consiste nello sviluppo di un metodo efficiente volto a superare la dicotomia esistente tra la documentazione di dettaglio e quella a scala più ampia, territoriale e paesaggistica, in maniera tale da innescare nuove riflessioni sugli ambiti archeologici indagati e contestualizzarli nella storia e negli spazi geografici differenziati per periodi che arrivino fino ai giorni nostri.Il poter misurare ed assorbire diversi universi contestuali (dal singolo muro all’architettura, fino al sito e al suo territorio, mettendoli a sistema e facendoli interagire nello spazio e nel tempo, è forse il contributo più importante che un lavoro di squadra multidisciplinare può offrire per la comprensione dello spazio in cui viviamo.Si presentano i risultati di due recenti attività svolte sul campo ancora in atto.

  5. Buone pratiche didattiche per prevenire falsi positivi nelle diagnosi di discalculia: il progetto “PerContare”

    OpenAIRE

    Anna Ethelwyn Baccaglini-Frank; Maria Giuseppina Bartolini Bussi

    2015-01-01

    Per contrastare il fenomeno dei falsi positivi nelle diagnosi di discalculia in Italia, tra i bambini di terza elementare, è stato realizzato un progetto triennale (2011-2014), fondato sulla collaborazione tra ricercatori in psicologia e didattica della matematica. Durante il progetto sono state elaborate e sperimentate pratiche didattiche atte a prevenire e affrontare difficoltà di apprendimento nell’ambito dell’aritmetica all’inizio della scuola primaria. In questo articolo vengono discusse...

  6. Campagna di social marketing per sensibilizzare all'uso delle cinture di sicurezza e dispositivi per bambini

    Directory of Open Access Journals (Sweden)

    S. Cinquetti

    2003-05-01

    Full Text Available

    Obiettivi: aumento del 10% dell’uso delle cinture di sicurezza anteriori e posteriori e del 20% dei seggiolini per bambini nella Regione del Veneto.

    Metodi: il Programma Regionale di Prevenzione dei Traumi da Traffico è stato varato nel 1998 e rifinanziato nel 2002 per un secondo triennio. Fa capo alla Direzione per la Prevenzione dell’Assessorato alle Politiche Sanitarie del Veneto, coinvolge i Dipartimenti di Prevenzione di tutte le Aziende ULSS del Veneto e ha come capofila l’azienda ULSS 7 di Pieve di Soligo (TV. Nell’ambito del programma, il 16 maggio 2003 è stata avviata una campagna di marketing sociale finanziata dalla fondazione CARIVERONA e commissionata ad un’ agenzia pubblicitaria leader del settore. La campagna è stata preceduta da ricerca formativa con 19 focus group e 12 interviste, volta ad analizzare il punto di vista dei diversi target, nonché degli attori principali coinvolti (Forze dell’Ordine, autoscuole, etc. Dopo un test di gradimento, la campagna è partita con spot televisivi e radiofonici, inserzioni nei giornali e manifesti informativi destinati alle scuole medie superiori, alle scuole guida nonché agli ambulatori dei medici di famiglia. Attraverso i media si sostiene una serie di azioni nel territorio che coinvolgeranno le amministrazioni comunali, le forze di polizia e le associazioni di volontariato.

    Risultati: l’efficacia della campagna viene valutata attraverso due distinte rilevazioni dell’uso delle cinture di sicurezza/seggiolini, confrontando i dati raccolti prima della campagna e dopo.

    Conclusioni: i traumi da traffico rappresentano nel Veneto un’importante causa di mortalità e morbosità. Il programma regionale ha utilizzato la tecnica innovativa del marketing sociale come strumento essenziale per sostenere i cambiamenti comportamentali necessari a prevenire l’incidentalità da traffico nel

  7. Circadian clock genes Per1 and Per2 regulate the response of metabolism-associated transcripts to sleep disruption.

    Directory of Open Access Journals (Sweden)

    Jana Husse

    Full Text Available Human and animal studies demonstrate that short sleep or poor sleep quality, e.g. in night shift workers, promote the development of obesity and diabetes. Effects of sleep disruption on glucose homeostasis and liver physiology are well documented. However, changes in adipokine levels after sleep disruption suggest that adipocytes might be another important peripheral target of sleep. Circadian clocks regulate metabolic homeostasis and clock disruption can result in obesity and the metabolic syndrome. The finding that sleep and clock disruption have very similar metabolic effects prompted us to ask whether the circadian clock machinery may mediate the metabolic consequences of sleep disruption. To test this we analyzed energy homeostasis and adipocyte transcriptome regulation in a mouse model of shift work, in which we prevented mice from sleeping during the first six hours of their normal inactive phase for five consecutive days (timed sleep restriction--TSR. We compared the effects of TSR between wild-type and Per1/2 double mutant mice with the prediction that the absence of a circadian clock in Per1/2 mutants would result in a blunted metabolic response to TSR. In wild-types, TSR induces significant transcriptional reprogramming of white adipose tissue, suggestive of increased lipogenesis, together with increased secretion of the adipokine leptin and increased food intake, hallmarks of obesity and associated leptin resistance. Some of these changes persist for at least one week after the end of TSR, indicating that even short episodes of sleep disruption can induce prolonged physiological impairments. In contrast, Per1/2 deficient mice show blunted effects of TSR on food intake, leptin levels and adipose transcription. We conclude that the absence of a functional clock in Per1/2 double mutants protects these mice from TSR-induced metabolic reprogramming, suggesting a role of the circadian timing system in regulating the physiological effects

  8. La iniciativa de vivienda saludable en el Perú

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    Rosario Santa María

    2008-10-01

    Full Text Available El objetivo del presente documento es identificar los principales indicadores relacionados con la salud de las familias en su domicilio y peridomicilio y, de tal manera, comprender la importancia de difundir en nuestro país la Iniciativa de Vivienda Saludable promovida por la Organización Panamericana de la Salud. Nos hemos focalizado en los factores de salud relacionados con la vivienda en las diferentes regiones del Perú, teniendo en cuenta las formas de vida locales, priorizando el análisis en los sectores socio-económicos de menores ingresos de las ciudades y con la consideración de que el tema de la vivienda saludable es un componente importante dentro de la salud ambiental. El contenido es resultado de entrevistas a profesionales con experiencia en los temas de salud y vivienda, así como contrastar información bibliográfica y periodística con nuestra apreciación subjetiva de la realidad, para llegar a conclusiones y recomendaciones generales. Ante las condiciones de la vivienda en el Perú y sus repercusiones en la salud de la población, se hizo necesario favorecer la conformación de una red nacional que agrupe a diversas instituciones públicas y privadas que vienen promoviendo en el Perú, desde diversos enfoques, el mejoramiento de las condiciones de la vivienda y de su entorno, con el propósito de complementar sus capacidades y apoyarse mutuamente en sus desempeños. Finalmente, consideramos que la vivienda saludable es un derecho y deber de las personas, en sintonía con el derecho a la salud y a la vida y la corresponsabilidad entre gobierno local y ciudadanía.

  9. O período toxêmico da esquistossomose

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    J. Leocádio

    1969-06-01

    Full Text Available O A. apresenta seis casos de pacientes observados durante o período toxêmico da esquistosomose mansônica. Dêstes, um foi de mulher cuja sintomatologia datava de um ano. Concebeu e deu à luz durante a enfermidade. Apresentava sinais de fibrose hepática quando do primeiro exame, ainda na vigência de sintomas do período agudo da enfermidade. Todos êstes pacientes apresentavam febre, dores abdominais, hepatoesplenomegalia e outras manifestações que têm sido descritas neste período da parasitose. Como notas dominantes no hemograma, leucocitose com eosinofilia, como ocorre nas infecções por helmintos com ciclo textrino, e anemia. Esta, nem todos apresentavam. Além de alterações do equilíbrio proteico e de resultados da exploração funcional do fígado, o A. chamou a atenção para a hípoglicemia e hipocolesterolemia encontradas em alguns dos observados. Foi digno de registro, também, a positividade tardia da intradermorreação para diagnóstico da esquistosomose. Todos os pacientes foram submetidos a tratamento antimonial, com bom resultado. Como reação colateral devemos mencionar a exacerbação da febre forçando, por vêzes à interrupção do mesmo. O A. faz referências a outros recursos terapêuticos empregados no Oriente: o F30.066, um nitrofurano de uso oral, e as sementes de Cucurbita moshata. Sugere a investigação em animais e no homem com sementes de abóbora outrora empregadas como tenifugo

  10. CALiPER Exploratory Study: Recessed Troffer Lighting

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Naomi J.; Royer, Michael P.; Poplawski, Michael E.

    2013-04-28

    This report describes an exploration of troffer lighting as used in office and classroom spaces, which was conducted by the CALiPER program. Twenty-four pairs of 2×2 and 2×4 troffers were procured anonymously, documented, tested for photometric and electrical performance, and installed in a mockup office space in Portland, Oregon. Three of the pairs were T8 fluorescent benchmark products, 12 were dedicated LED troffers, five were fluorescent troffers modified for LED lamps (sometimes referred to as "tubes"), and another four troffers were modified with LED retrofit kits. The modifications were performed by a commercial electrical contractor, following the instructions provided by the retrofit lamp or kit manufacturer. Once installed in the mockup facility, the converted luminaires were examined by a NRTL (Nationally Recognized Testing Laboratory) safety expert, who provided feedback on safety issues. In September 2012, a group of lighting designers, engineers, and facility managers were brought in to observe the LED luminaires in comparison to fluorescent benchmarks. This report documents performance in measures that go beyond illuminance values or luminaire efficacy. Dedicated LED troffers are ready to compete with fluorescent troffers in terms of efficacy (lumens per watt), and in many lighting quality issues such as glare, light distribution, visual appearance, and color quality. That is not to say that each one is stellar, but each one tested in this CALiPER study bested the fluorescent benchmarks in terms of efficacy, and almost all were rated highly in several categories -- only one luminaire of twelve performed consistently poorly.

  11. Indicazioni Geografiche, Strategie di Differenziazione e Politiche per il Consumatore

    OpenAIRE

    Capelli, Maria Giacinta

    2014-01-01

    Il presente lavoro si pone un duplice obiettivo: analizzare il contesto dei marchi di origine in Italia e indagare la domanda e l’offerta di Prosciutto di Parma DOP. Per raggiungere questo scopo la ricerca è stata organizzata in tre parti: la prima, attraverso l’articolo “The resilient character of PDO/PGI products in dynamic food markets: the Italian case” (Arfini e Capelli, 2011), si propone di fornire un quadro esaustivo delle caratteristiche economiche delle denominazioni DOP e IGP it...

  12. Flacourtiaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Flacourtiaceae es reconocida en el Perú por presentar 19 géneros y 65 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, mayormente arbustos y árboles. En este trabajo reconocemos tres especies endémicas en dos géneros, las cuales ocupan la región de los Bosques Muy Húmedos Montanos, entre los 2300 y 3600 m de altitud. Solamente una de estas especies se encuentra representada en el Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  13. LabTD: un laboratorio di tecnologie didattiche per docenti

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    Maria Ferraris

    2007-01-01

    Full Text Available Descrizione del progetto e l’avvio di un ambiente prototipo, dentro ad una scuola, dedicato al lavoro degli insegnanti e alla loro formazione permanente. LabTD e’ stato immaginato come un ambiente attrezzato per docenti, la cui ragion d’essere non sta tanto nei temi affrontati o nelle tecnologie di cui e’ dotato, quanto nell’idea che la crescita professionale degli insegnanti dipenda in gran parte dalle opportunita’, dalle risorse e dagli stimoli offerti dal contesto in cui operano.

  14. Book Review, Per non scoprirlo mangiando… ,Maria Caramelli

    Directory of Open Access Journals (Sweden)

    Manuel Graziani

    2013-06-01

    Full Text Available L'incidenza delle malattie trasmesse dagli alimenti sta crescendo in maniera esponenziale, le insidie nascoste negli alimenti sono sempre di più e di varia natura. Questo accade soprattutto in Occidente: "Nei Paesi del terzo mondo ci si ammala e si muore per l'assenza di cibo. Nei Paesi industrializzati, invece, ogni anno più di una persona su quattro contrae malattie associate al consumo di alimenti." Si stima che nel 2010 in Europa più di 45.000 persone si siano ammalate a causa di acqua o cibo contaminati; secondo i dati dell'Istituto Superiore di Sanità in Italia sono circa 30.000 all'anno le tossinfezioni alimentari. Un incremento di malattie alimentari che, per paradosso, è frutto dell'evoluzione di un mondo senza più frontiere nel quale gli scambi di animali, mangimi e materie prime di origine animale sono oramai incontrollabili.Nonostante i consumatori europei pongano i rischi chimici (come gli additivi in cima alle preoccupazioni per la propria sicurezza alimentare, secondo la FAO e l'OMS i pericoli maggiori sono invece di natura microbiologica, riguardano cioè virus e batteri in grado di provocare intossicazioni e infezioni con conseguenze anche drammatiche: microrganismi spesso difficili da identificare e in continua espansione, favoriti dalla globalizzazione, dalla trasformazione delle nostre abitudini, dalla complessità dei processi di produzione e distribuzione dei cibi.L'agile libro della dott.ssa Maria Caramelli, Direttore generale dell'IZS di Piemonte Liguria e Valle d'Aosta ed esperta di sicurezza alimentare (una delle più autorevoli studiose italiane di BSE, indaga il vasto mondo delle malattie alimentari partendo dai casi che hanno scatenato allarmi sanitari e crisi economiche di vaste proporzioni scuotendo mass media e opinione pubblica: mucca pazza (BSE, influenza aviaria, diossina nei maiali, mozzarella blu "color puffo", ricotta rosa, fino all'epidemia tedesca del batterio killer nei germogli che tra maggio e

  15. Book Review, Per non scoprirlo mangiando… ,Maria Caramelli

    OpenAIRE

    Manuel Graziani

    2013-01-01

    L'incidenza delle malattie trasmesse dagli alimenti sta crescendo in maniera esponenziale, le insidie nascoste negli alimenti sono sempre di più e di varia natura. Questo accade soprattutto in Occidente: "Nei Paesi del terzo mondo ci si ammala e si muore per l'assenza di cibo. Nei Paesi industrializzati, invece, ogni anno più di una persona su quattro contrae malattie associate al consumo di alimenti." Si stima che nel 2010 in Europa più di 45.000 persone si siano ammalate a causa di acqua o ...

  16. Tripolitania e Cirenaica: un futuro per il patrimonio

    OpenAIRE

    Mastino, Attilio

    2012-01-01

    In Libia, nel fondo del Mediterraneo, al centro della Grande Sirte, c'è un luogo che non è un luogo, Ras Ali (Graret Gser et Trab), le antiche Arae Philenorum, il favoloso muchòs, il sacco del Mediterraneo, dove cultura punica e cultura ellenistica si sono toccate, più tardi cultura latina e cultura greca, e poi vandala, bizantina e araba; Sallustio ricorda: quem locum Aegyptum versus finem imperli habuere Carthaginienses, là dove i due fratelli Fileni si sarebbero fatti uccidere per se...

  17. Green economy: un'occasione per le aree montane

    Directory of Open Access Journals (Sweden)

    Maria Sapone

    2013-06-01

    Full Text Available È ormai opinione largamente condivisa che l’attuale “crisi” dell’organismo territoriale non sia soltanto economica ma anche ambientale. Quest’ultima tematica unita a quella della green economy potrebbero rappresentare l'occasione di intervenire sui sistemi territoriali non urbani, un tempo vitali per l’economia locale, ed oggi abbandonati a se stessi a favore delle aree urbanizzate, luoghi economicamente più vantaggiosi. Partendo dalle indicazioni del Programma per l’Ambiente delle Nazioni Unite (UNEP si potrebbero definire politiche di sviluppo al fine di migliorare la competitività e l'attrattività dei sistemi territoriali rurali attraverso la valorizzazione delle risorse endogene presenti su tali territori, con l’obiettivo di favorire lo sviluppo ecosostenibile delle diverse attività al fine di creare una rete integrata. La ricerca svolta presenta le diverse dinamiche legate alla creazione di una rete di Eco-Villaggi, con lo scopo di rifunzionalizzare il patrimonio edilizio e urbanistico esistente, migliorando, così, la qualità della vita dei centri montani. Questo modello può rappresentare concretamente una delle possibili soluzioni allo spopolamento, nel conservare e tutelare lo spazio naturale attraverso la promozione della green economy, basata sull’utilizzo di sistemi di produzione sostenibili, nel rispetto dei requisiti ambientali, nell’attivazione di sistemi energetici rinnovabili e nel richiamo turistico del patrimonio storico-culturale della montagna. Infatti queste risorse se gestite nel modo corretto, attraverso una attenta pianificazione territoriale, potrebbero rappresentare il volano per un modello di sviluppo sostenibile e allo stesso tempo potrebbero avviare una riqualificazione e valorizzazione dei borghi rurali, che spesso ospitano un patrimonio architettonico di notevole pregio. Risulta necessario, per i contesti rurali, porre in atto strumenti, modalità e forme innovative d’intervento capaci

  18. Cyclanthaceae endémicas del Perú

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    Blanca León

    2013-10-01

    Full Text Available La familia Cyclanthaceae es reconocida en el Perú por presentar nueve géneros y 37 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, mayormente hierbas y lianas. En este trabajo reconocemos siete endemismos en tres géneros. Los taxones endémicos ocupan dos de las regiones ecológicas, Bosque Húmedo Amazónico y Bosque Húmedo Premontano, entre los 180 y 1100 m de altitud. Dos de estos taxones endémicos se encuentran representados en áreas naturales protegidas.

  19. La oferta de trabajo en el Perú.

    OpenAIRE

    Reyna García, Debora Rosilene

    2015-01-01

    En esta tesis se estima la elasticidad de la oferta laboral para Perú en el periodo 2004-2012. Para ello, se utiliza la técnica de panel dinámico desarrollada por Arellano-Bond (1991), esto permite lidiar con los problemas de sesgos de selección y variables no observables. Las variables explicativas a utilizarse son el género, la edad, el tamaño de la empresa, la experiencia y el nivel educativo. Utilizando datos de la Encuesta Nacional de Hogares se encuentra que la elasticidad de la ofer...

  20. Convolvulaceae endémicas del Perú

    OpenAIRE

    Blanca León

    2013-01-01

    La familia Convolvulaceae es reconocida en el Perú por presentar 17 géneros y 132 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004), mayormente bejucos y lianas. En este trabajo reconocemos nueve especies y una subespecie como endemismos peruanos en cuatro géneros. Los taxones endémicos ocupan principalmente las regiones Matorral Desértico, Bosques Secos y Desierto Cálido Tropical, entre los 100 y 2000 m de altitud. Ninguna de estas especies se encuentra representada en el Siste...

  1. Convolvulaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Convolvulaceae es reconocida en el Perú por presentar 17 géneros y 132 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, mayormente bejucos y lianas. En este trabajo reconocemos nueve especies y una subespecie como endemismos peruanos en cuatro géneros. Los taxones endémicos ocupan principalmente las regiones Matorral Desértico, Bosques Secos y Desierto Cálido Tropical, entre los 100 y 2000 m de altitud. Ninguna de estas especies se encuentra representada en el Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  2. MELAS en el Perú: reporte de caso.

    OpenAIRE

    Escalante-Gavancho, Carlos; Vattuone-Echevarría, Jorge A.; Candia-Rivera, Elizabeth; Isidro-Huarcaya, Jaime; Escalante-Canorio, Jorge

    2015-01-01

    El síndrome de MELAS es una rara citopatía mitocondrial de difícil diagnóstico. Reportamos el caso de una niña de 10 años, que ingresó al Instituto Nacional de Ciencias Neurológicas de Lima, Perú, quien presentó episodios bruscos similares a accidentes cerebrovasculares y crisis epilépticas. Los estudios de neuroimágenes mostraron infartos y el examen genético fue positivo para MELAS identificando la mutación más frecuente A3243G.

  3. Burmanniaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Burmanniaceae es reconocida en el Perú por presentar ocho géneros y 16 especies (Brako & Zarucchi, 1993, principalmente hierbas saprófitas. En este trabajo reconocemos un endemismo en el genero Burmannia. Esta especie endémica posee un amplio grado de adaptación ambiental, habiéndosele localizado en las vertientes occidentales, valles interandinos, páramos y bosques montanos orientales, entre los 1200 y 4100 m de altitud. Esta especie se encuentra representada en un área natural protegida.

  4. Chloranthaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Chloranthaceae es reconocida en el Perú por presentar un género, Hedyosmum, y 14 especies (Brako & Zarucchi, 1993, todos ellas árboles y/o arbustos. En este trabajo reconocemos una especie endémica, la cual ocupa la región Bosques Muy Húmedos Montanos, entre los 1900 y 2650 m de altitud, y está representada dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  5. Circuiti fondamenti di circuiti per l'ingegneria

    CERN Document Server

    de Magistris, Massimiliano

    2016-01-01

    Questo libro è un testo introduttivo ai circuiti per i corsi delle Facoltà di Ingegneria, al primo livello. Esso parte dai concetti di intensità di corrente, tensione e potenza elettrica, introducendo le leggi di Kirchhoff ed il modello circuitale su base fisica. Vengono poi introdotti gli elementi circuitali fondamentali ed illustrate le proprietà generali dei circuiti. Successivamente sono trattati i circuiti lineari e tempo invarianti in maniera completa, sviluppandone le principali tecniche di analisi. Nonostante il taglio introduttivo e l’attenzione ad uno stile piano ed accessibile, il testo si propone di affrontare il modello circuitale in modo rigoroso ed al tempo stesso moderno.

  6. La fisica del Novecento per un bilancio critico

    CERN Document Server

    Selleri, Franco

    1999-01-01

    Ma chi ha detto che la fine della fisica è vicina? Che tutto quello che c'era da scoprire è già stato scoperto? E che le generazioni future potranno solo precisare e raffinare, e mai negare o arricchire le attuali teorie? Questo libro si contrappone a pensatori come Heisenberg, Feyman e Hawking che hanno predetto la morte della fisica. L'autore sostiene che grandi progressi sono possibili, ma che il prezzo da pagare per realizzarli è una modifica radicale delle basi della fisica moderna, in particolare abbandonando l'indeterminismo, la non località (paradosso di Einstein, Podolsky e Rosen) e lo stesso principio di relatività.

  7. Rutaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Rutaceae es reconocida en el Perú por presentar 25 géneros y 76 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, principalmente árboles y arbustos. En este trabajo reconocemos seis endemismos, representando igual número de géneros. Los taxones endémicos se encuentran en las regiones Bosques Húmedos Amazónicos, Bosques Muy Húmedos Premontanos y Mesoandina, entre los 130 y 2000 m de altitud. Tres taxones se encuentran representados dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  8. Buxaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Buxaceae es reconocida en el Perú por presentar un género, Styloceras, y tres especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, todos arbustos. En este trabajo reconocemos un endemismo. Esta especie endémica se encuentra en la región Bosques Muy Húmedos Montanos, entre los 1800 y 1850 m de altitud. No está representada en el Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  9. Olacaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Olacaceae es reconocida en el Perú por presentar nueve géneros y 23 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, la mayoría árboles y arbustos. En este trabajo reconocemos un endemismo en el género Aptandra. Esta especie se encuentra en la región Bosques Húmedos Amazónicos, entre los 100 y 150 m de altitud. No está registrada en el Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  10. Vochysiaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Vochysiaceae es reconocida en el Perú por presentar cuatro géneros y 32 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, todas árboles. En este trabajo reconocemos dos especies endémicas en el género Qualea. Estas especies endémicas han sido encontradas en la región Bosques Húmedos Amazónicos, entre los 100 y 160 m de altitud. Ninguna especie endémica se encuentra representada dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  11. Rosaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Wilfredo Mendoza

    2013-10-01

    Full Text Available La familia Rosaceae es reconocida en el Perú por presentar 24 géneros y 113 especies (Brako & Zarucchi, 1993; Mendoza, 2005; Ulloa Ulloa et al., 2004, entre hierbas, arbustos y árboles. En este trabajo reconocemos 14 especies endémicas en cuatro géneros. Las especies endémicas se encuentran principalmente en las regiones Bosques Pluviales Montanos, Bosques Muy Húmedos Montanos y Páramo, entre los 1900 y 3800 m de altitud. Seis especies endémicas se encuentran representadas dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  12. Buddlejaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Buddlejaceae es reconocida en el Perú por presentar dos géneros y 16 especies (Norman, 2000; Ulloa Ulloa et al., 2004, principalmente arbustos. En este trabajo reconocemos dos especies endémicas en el género Buddleja. Estos taxones endémicos se encuentran en las regiones Mesoandina, Puna Húmeda y Seca y Páramo, entre los 2650 y 3900 m de altitud. Una de estas dos especies se encuentra representada dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  13. Begoniaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Begoniaceae es reconocida en el Perú por presentar un género, Begonia, y 76 especies (Brako & Zarucchi, 1993, mayormente hierbas. En este trabajo reconocemos 38 endemismos. La mayoría de estos taxones endémicos ocupan las regiones de Bosques Húmedos Amazónicos y Bosques Muy Húmedos Montanos y Premontanos, entre los 400 y 2500 m de altitud. Se aplicaron las categorías y criterios de la UICN a diez taxones. Aparentemente, sólo una de estas especies se encuentra representada dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  14. Tropaeolaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available Esta es la familia de la «mashua». La familia Tropaeolaceae es reconocida en el Perú por presentar un género, Tropaeolum, y 24 especies (Brako & Zarucchi, 1993, todas herbáceas y bejucos. En este trabajo reconocemos 10 especies endémicas, las cuales se encuentran principalmente en las regiones Bosques Muy Húmedos Montanos y Mesoandina, entre los 1800 y 3200 m de altitud. Una especie, aparentemente, se encuentra representada dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  15. Wissenschaftliche Persönlichkeiten fallen nicht vom Himmel

    Directory of Open Access Journals (Sweden)

    Anina Mischau

    2003-03-01

    Full Text Available Steffani Engler geht in ihrer Studie der Frage nach, wie und durch was eine wissenschaftliche Persönlichkeit im sozialen Feld der Wissenschaft konstruiert wird. Hierzu beschreibt und analysiert sie den Karriereweg von vier Professoren und zwei Professorinnen. Obgleich sich die Autorin damit in der Biographieforschung verortet, beschreitet sie für ihre Fragestellung, auch in Abgrenzung zu gängigen Methoden und Ansätzen dieser Forschungsrichtung, neue Wege: Ihre Interpretation und Analyse nimmt sie in Anlehnung an das von Pierre Bourdieu entwickelte „Konzept des Verstehens“ vor und vollzieht dabei einen Blickwechsel weg vom Individuum hin zur Funktionsweise des wissenschaftlichen Feldes.

  16. Android application for handwriting segmentation using PerTOHS theory

    Science.gov (United States)

    Akouaydi, Hanen; Njah, Sourour; Alimi, Adel M.

    2017-03-01

    The paper handles the problem of segmentation of handwriting on mobile devices. Many applications have been developed in order to facilitate the recognition of handwriting and to skip the limited numbers of keys in keyboards and try to introduce a space of drawing for writing instead of using keyboards. In this one, we will present a mobile theory for the segmentation of for handwriting uses PerTOHS theory, Perceptual Theory of On line Handwriting Segmentation, where handwriting is defined as a sequence of elementary and perceptual codes. In fact, the theory analyzes the written script and tries to learn the handwriting visual codes features in order to generate new ones via the generated perceptual sequences. To get this classification we try to apply the Beta-elliptic model, fuzzy detector and also genetic algorithms in order to get the EPCs (Elementary Perceptual Codes) and GPCs (Global Perceptual Codes) that composed the script. So, we will present our Android application M-PerTOHS for segmentation of handwriting.

  17. Dorsomedial prefontal cortex supports spontaneous thinking per se.

    Science.gov (United States)

    Raij, T T; Riekki, T J J

    2017-06-01

    Spontaneous thinking, an action to produce, consider, integrate, and reason through mental representations, is central to our daily experience and has been suggested to serve crucial adaptive purposes. Such thinking occurs among other experiences during mind wandering that is associated with activation of the default mode network among other brain circuitries. Whether and how such brain activation is linked to the experience of spontaneous thinking per se remains poorly known. We studied 51 healthy subjects using a comprehensive experience-sampling paradigm during 3T functional magnetic resonance imaging. In comparison with fixation, the experiences of spontaneous thinking and spontaneous perception were related to activation of wide-spread brain circuitries, including the cortical midline structures, the anterior cingulate cortex and the visual cortex. In direct comparison of the spontaneous thinking versus spontaneous perception, activation was observed in the anterior dorsomedial prefrontal cortex. Modality congruence of spontaneous-experience-related brain activation was suggested by several findings, including association of the lingual gyrus with visual in comparison with non-verbal-non-visual thinking. In the context of current literature, these findings suggest that the cortical midline structures are involved in the integrative core substrate of spontaneous thinking that is coupled with other brain systems depending on the characteristics of thinking. Furthermore, involvement of the anterior dorsomedial prefrontal cortex suggests the control of high-order abstract functions to characterize spontaneous thinking per se. Hum Brain Mapp 38:3277-3288, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  18. Regional Per Capita Solar Electric Footprint for the United States

    Energy Technology Data Exchange (ETDEWEB)

    Denholm, P.; Margolis, R.

    2007-12-01

    In this report, we quantify the state-by-state per-capita 'solar electric footprint' for the United States. We use state-level data on population, electricity consumption, economic activity and solar insolation, along with solar photovoltaic (PV) array packing density data to develop a range of estimates of the solar electric footprint. We find that the solar electric footprint, defined as the land area required to supply all end-use electricity from solar photovoltaics, is about 181 m2 per person in the United States. Two key factors that influence the magnitude of the state-level solar electric footprint include how industrial energy is allocated (based on location of use vs. where goods are consumed) and the assumed distribution of PV configurations (flat rooftop vs. fixed tilt vs. tracking). The solar electric footprint is about 0.6% of the total land area of the United States with state-level estimates ranging from less than 0.1% for Wyoming to about 9% for New Jersey. We also compare the solar electric footprint to a number of other land uses. For example, we find that the solar electric footprint is equal to less than 2% of the land dedicated to cropland and grazing in the United States.

  19. Ka-Band, Multi-Gigabit-Per-Second Transceiver

    Science.gov (United States)

    Simons, Rainee N.; Wintucky, Edwin G.; Smith, Francis J.; Harris, Johnny M.; Landon, David G.; Haddadin, Osama S.; McIntire, William K.; Sun, June Y.

    2011-01-01

    A document discusses a multi-Gigabit-per-second, Ka-band transceiver with a software-defined modem (SDM) capable of digitally encoding/decoding data and compensating for linear and nonlinear distortions in the end-to-end system, including the traveling-wave tube amplifier (TWTA). This innovation can increase data rates of space-to-ground communication links, and has potential application to NASA s future spacebased Earth observation system. The SDM incorporates an extended version of the industry-standard DVB-S2, and LDPC rate 9/10 FEC codec. The SDM supports a suite of waveforms, including QPSK, 8-PSK, 16-APSK, 32- APSK, 64-APSK, and 128-QAM. The Ka-band and TWTA deliver an output power on the order of 200 W with efficiency greater than 60%, and a passband of at least 3 GHz. The modem and the TWTA together enable a data rate of 20 Gbps with a low bit error rate (BER). The payload data rates for spacecraft in NASA s integrated space communications network can be increased by an order of magnitude (>10 ) over current state-of-practice. This innovation enhances the data rate by using bandwidth-efficient modulation techniques, which transmit a higher number of bits per Hertz of bandwidth than the currently used quadrature phase shift keying (QPSK) waveforms.

  20. Orchidaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    José Roque

    2013-10-01

    Full Text Available La familia Orchidaceae constituye para la flora peruana la familia más diversa, con alrededor de 212 géneros y 2020 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, aunque se estima que el número real podría oscilar entre 2500 y 3500 especies (Collantes, com. pers.. La mayoría son hierbas epífitas o terrestres, aunque hay también las que presentan ambos hábitos. En este trabajo reconocemos 775 endemismos en 137 géneros, lo que la constituye también en la familia con más taxones restringidos al Perú. Estos endemismos han sido encontrados en varias regiones ecológicas, principalmente en la Bosques Muy Húmedos Montanos, Bosques Muy Húmedos Premontanos y Mesoandina, entre los 100 y 4600 m de altitud. La destrucción de sus hábitats y el comercio ilegal de plantas silvestres la hacen particularmente vulnerable desde el punto de vista de conservación. Ciento cinco taxones se encuentran en áreas naturales protegidas.

  1. LHC Report: 1,033 bunches per beam and counting

    CERN Multimedia

    Jorg Wenninger for the LHC team

    2015-01-01

    Following the second technical stop, the first beams were injected into the LHC in the early evening of Saturday, 5 September. About ten days later, the machine was operated with around 1,000 bunches per beam.    Evolution of the stored energy per LHC beam, over time.   The first step after a technical stop consists of running through a full LHC cycle, from injection to collisions and beam dump, with a low-intensity bunch (“probe”) to check all machine settings and equipment. This is followed by a series of collimation and absorber validation tests at different points in the LHC cycle. Low-intensity beams – typically the equivalent of three nominal bunches (3 x 1011 protons) – are expanded transversely or longitudinally, or de-bunched to verify that the collimators and absorbers are correctly intercepting lost particles. The techniques for those validations have been progressively improved, and t...

  2. Urban movements and disempowerment in Perú and Venezuela

    Directory of Open Access Journals (Sweden)

    Daniel H. LEVINE

    2010-10-01

    Full Text Available This paper addresses a core puzzle: why is continued citizen mobilization accompanied by growing disempowerment of those same citizens? Why do movements fail, leaders burn out and members disperse, and what are the implications of this organizational failure for demo¬cratic representation? Our consideration of the issues is rooted in a close examination of urban movements, mobilization, empowerment and disempowerment in the recent experience of Venezuela and Perú. The puzzle that concerns us is of course not limited to these two countries: it is common to all the Andean republics, and in different ways, to much recent experience of urban mobilization in Latin America and beyond. After a brief account of urban citizen move¬ments and politics in our two cases, we outline general reflections on the nature of empowerment and disempowerment, on the peculiar combination of strengths and weaknesses that mark many contemporary movements. A close examination of types of movements and their links with poli¬tical parties and protest follows. The character of city life is important here. We close with analysis of recent waves of urban mobilization in Perú (that sparked the ouster of president Alberto Fujimori and in Venezuela (both for and against president Hugo Chávez Frías, and with reflections on the likely future of empowerment and disempowerment for urban citizens and the implications of this perspective for democratic representation

  3. Fabaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Severo Baldeón

    2013-10-01

    Full Text Available La familia Fabaceae es reconocida en el Perú por presentar alrededor de 145 géneros y 1000 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, mayormente árboles y arbustos. En este trabajo reconocemos 234 especies y 40 variedades como endémicas en 47 géneros. Un género, Weberbauerella, es endémico del Perú. Sin lugar a dudas, el género con mayor número de especies endémicas es Lupinus, siendo al mismo tiempo el que mayor necesidad tiene de estudios taxonómicos detallados y mayor recolección. Las Fabaceae endémicas ocupan la mayoría de regiones, principalmente la Mesoandina, Puna Húmeda y Seca y Bosques Muy Húmedos Montanos, entre los 1100 y 4800 m de altitud. Se aplicaron las categorías y criterios de la UICN a 203 taxones. Diecisiete taxones endémicos se encuentran representados dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  4. Elementi di interfaccia per l’analisi di strutture murarie

    Directory of Open Access Journals (Sweden)

    Jessica Toti

    2009-04-01

    Full Text Available Il presente articolo riguarda la modellazione del comportamento meccanico di elementi in muratura intesi come sistemi eterogenei composti da malta, blocchi ed interfacce di connessione. La strategiacomputazionale che viene adottata consiste nel modellare separatamente i blocchi, i letti di malta ed le interfacce responsabili di fenomeni di decoesione malta-blocco; a tale scopo, si propone uno speciale modello di interfaccia che combina il danneggiamento con l’attrito. Si sviluppa una procedura numerica, basata sull’algoritmo backward di Eulero, per risolvere il problema evolutivo; per il passo temporale si utilizza invece la tecnica predictor-corrector a controllo di spostamenti. Si effettuano alcune applicazioni numeriche con lo scopodi verificare la capacità del modello e dell’algoritmo proposto nel riprodurre la risposta non lineare della muratura dovuta a fenomeni di degrado localizzati. Infine, si conduce lo studio della modellazione di un arco murario, confrontando i risultati numerici con quelli sperimentali; si dimostra la abilità del modello proposto nel simulare il comportamento globale della struttura ad arco in termini di carico ultimo e di meccanismo di collasso.

  5. Un corrector gramatical basat en cerques per Internet

    Directory of Open Access Journals (Sweden)

    Joaquim Moré

    2006-05-01

    Full Text Available En aquest article presentem un corrector gramatical de l'anglès destinat a escriptors no angloparlants. La principal característica d'aquest corrector és l'ús d'un motor de cerca per Internet. Com que hi ha un gran nombre de pàgines web escrites en anglès, el sistema fa la hipòtesi que un segment de text que no és present en cap pàgina web és probablement un segment de text mal escrit. El sistema també fa la hipòtesi que a la Xarxa hi trobarà exemples que ensenyaran a l'usuari com ha d'expressar el contingut del segment de text d'una manera gramatical i idiomàtica. Per tant, un cop el corrector avisa l'usuari que és millor verificar un segment del seu text, el motor cerca contextos que poden ser útils a la persona que escriu a l'hora de decidir si corregeix el segment o no. Gràcies també a l'ús d'un motor de cerca, el corrector suggereix a l'escriptor que utilitzi expressions que són més freqüents a la Xarxa en comptes de l'expressió que ha escrit. Text complet (PDF

  6. Per una teoria politica dell’impresa cooperativa

    Directory of Open Access Journals (Sweden)

    Stefano Zan

    2014-07-01

    Full Text Available Il saggio propone una traccia di ricerca per l’elaborazione di una teoria politica della cooperazione, ovvero per la considerazione del fenomeno cooperativo come caratterizzato da una peculiare modalità di azione collettiva, non ricompresa nella celebre distinzione hirschmaniana tra Exit, Voice e Loyalty. Chi partecipa all’impresa cooperativa non crede nelle possibilità di successo sia dell’opzione voice che di quella exit, ma pratica una forma diversa di azione che si basa sulla fiducia in se stessi e nei soci che hanno interessi comuni. Questa forma di azione collettiva può essere preliminarmente definita come entry. L’entry riporta all’interno del mercato chi aveva scelto l’opzione exit, conservando al tempo stesso quella carica di contestazione delle relazioni capitalistiche tipica dell’opzione voice. L’impresa cooperativa, in virtù di questa doppia caratteristica dell’azione dei suoi soci, rappresenta quindi un’opzione, oltre che economica, anche politica.

  7. The outer disk of the classical Be star ψ Per

    Science.gov (United States)

    Klement, Robert; Carciofi, Alex C.; Rivinius, Thomas; Matthews, Lynn D.; Ignace, Richard; Bjorkman, Jon E.; Vieira, Rodrigo G.; Mota, Bruno C.; Faes, Daniel M.; Štefl, Stanislav

    2017-11-01

    To this date ψ Per is the only classical Be star that was angularly resolved in radio (by the VLA at λ = 2 cm). Gaussian fit to the azimuthally averaged visibility data indicates a disk size (FWHM) of ~500 stellar radii (Dougherty & Taylor 1992). Recently, we obtained new multi-band cm flux density measurements of ψ Per from the enhanced VLA. We modeled the observed spectral energy distribution (SED) covering the interval from ultraviolet to radio using the Monte Carlo radiative transfer code HDUST (Carciofi & Bjorkman 2006). An SED turndown, that occurs between far-IR and radio wavelengths, is explained by a truncated viscous decretion disk (VDD), although the shallow slope of the radio SED suggests that the disk is not simply cut off, as is assumed in our model. The best-fit size of a truncated disk derived from the modeling of the radio SED is 100+5 -15 stellar radii, which is in striking contrast with the result of Dougherty & Taylor (1992). The reasons for this discrepancy are under investigation.

  8. Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle.

    Science.gov (United States)

    Silva, Heloisa Cristina; Prette, Nancy; Lopes, Welber Daniel Zanetti; Sakamoto, Cláudio Alessandro M; Buzzulini, Carolina; Dos Santos, Thais Rabelo; Cruz, Breno Cayeiro; Teixeira, Weslen F Pires; Felippelli, Gustavo; Carvalho, Rafael Silveira; Maciel, Willian Giquelin; Soares, Vando Edésio; da Costa, Alvimar José

    2015-01-01

    The present work aimed to evaluate, through ten different studies, the therapeutic efficacy of a new pour-on formulation, containing 1.5 per cent ivermectin +0.5 per cent abamectin, against parasites of cattle. Results obtained on trials against Rhipicephalus (Boophilus) microplus showed that the pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained superior efficacy indexes against this ectoparasite, when compared with formulations containing 0.5 per cent ivermectin, 1 per cent ivermectin and the combination of 1 per cent abamectin +20 per cent levamisole. The results of efficacy of the ivermectin+abamectin and the 0.5 per cent ivermectin against Haematobia irritans were similar. Against Cochliomyia hominivorax larvae, all pour-on formulations tested (1.5 per cent ivermectin +0.5 per cent abamectin, 0.5 per cent ivermectin and 0.5 per cent abamectin), as well as 1 per cent doramectin administered subcutaneously, were considered ineffective. Cattle medicated with 1.5 per cent ivermectin +0.5 per cent abamectin, pour-on, remained free from parasitism by Dermatobia hominis larvae during 42 days (96 per cent efficacy), while values superior to 90 per cent were obtained by 0.5 per cent ivermectin (92 per cent) and 0.5 per cent abamectin (93 per cent) until the 42nd and 35th days post treatment, respectively. Against Haemonchus placei and Oesophagostomum radiatum, the pour-on of ivermectin+abamectin showed better efficacy than the 0.5 per cent ivermectin and 0.5 per cent abamectin. As to Cooperia punctata, there was no difference regarding efficacy results obtained by the avermectins combination and abamectin. The pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained high efficacy against R. (B.) microplus, D. hominis and some species of cattle gastrointestinal helminths when compared with formulations of 0.5 per cent ivermectin and 0.5 per cent abamectin administered through the same route.

  9. Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle

    Science.gov (United States)

    Silva, Heloisa Cristina; Prette, Nancy; Lopes, Welber Daniel Zanetti; Sakamoto, Cláudio Alessandro M; Buzzulini, Carolina; dos Santos, Thais Rabelo; Cruz, Breno Cayeiro; Teixeira, Weslen F Pires; Felippelli, Gustavo; Carvalho, Rafael Silveira; Maciel, Willian Giquelin; Soares, Vando Edésio; da Costa, Alvimar José

    2015-01-01

    The present work aimed to evaluate, through ten different studies, the therapeutic efficacy of a new pour-on formulation, containing 1.5 per cent ivermectin +0.5 per cent abamectin, against parasites of cattle. Results obtained on trials against Rhipicephalus (Boophilus) microplus showed that the pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained superior efficacy indexes against this ectoparasite, when compared with formulations containing 0.5 per cent ivermectin, 1 per cent ivermectin and the combination of 1 per cent abamectin +20 per cent levamisole. The results of efficacy of the ivermectin+abamectin and the 0.5 per cent ivermectin against Haematobia irritans were similar. Against Cochliomyia hominivorax larvae, all pour-on formulations tested (1.5 per cent ivermectin +0.5 per cent abamectin, 0.5 per cent ivermectin and 0.5 per cent abamectin), as well as 1 per cent doramectin administered subcutaneously, were considered ineffective. Cattle medicated with 1.5 per cent ivermectin +0.5 per cent abamectin, pour-on, remained free from parasitism by Dermatobia hominis larvae during 42 days (96 per cent efficacy), while values superior to 90 per cent were obtained by 0.5 per cent ivermectin (92 per cent) and 0.5 per cent abamectin (93 per cent) until the 42nd and 35th days post treatment, respectively. Against Haemonchus placei and Oesophagostomum radiatum, the pour-on of ivermectin+abamectin showed better efficacy than the 0.5 per cent ivermectin and 0.5 per cent abamectin. As to Cooperia punctata, there was no difference regarding efficacy results obtained by the avermectins combination and abamectin. The pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained high efficacy against R. (B.) microplus, D. hominis and some species of cattle gastrointestinal helminths when compared with formulations of 0.5 per cent ivermectin and 0.5 per cent abamectin administered through the same route. PMID:26392893

  10. Tephrosia vogelii for control of fleas in free-range poultry

    African Journals Online (AJOL)

    ACSS

    The difference in re-infestation between the treated and control chickens on Days 6, 7 and 8 was significant (p < 0.001). Permethrin ... dried and fresh leaves extracts were 50 ml of the standard extract in 1200 and 800 ml at room temperature, respectively. ... Newcastle Disease and infectious bronchitis among many others; ...

  11. Tephrosia vogelii for control of fleas in free-range poultry | Isabirye ...

    African Journals Online (AJOL)

    Chicken production is the leading type of poultry farming in eastern Africa. However, diseases and parasites are limiting factors in production. Ectoparasites in particular lead to reduced egg production, and reduced hatchability, since the hens usually abandon eggs following ectoparasitic infestation. Ethno-veterinary ...

  12. UN LASCIAPASSARE PER L’ITALIA. LA LEGGE MARONI E L’OBBLIGO DEL TEST DI ITALIANO PER STRANIERI

    Directory of Open Access Journals (Sweden)

    Giuseppe Sergio

    2011-07-01

    Full Text Available Per legge, dalla fine del 2010, gli stranieri già residenti nel nostro Paese e intenzionati a richiedere il “permesso CE per soggiornanti di lungo periodo” devono dimostrare di possedere un livello minimo di conoscenza dell’italiano. L’articolo ripercorre il contenuto di questa normativa, soffermandosi sui suoi aspetti operativi e sulle procedure per la somministrazione del test volto all’elicitazione e verifica del profilo di competenza richiesto (corrispondente all’A2 del QCER. Se la legge dimostra di considerare la lingua come irrinunciabile fattore coesivo, allineandosi peraltro a quanto già stabilito in numerosi Paesi europei, diversamente da questi ultimi in Italia il settore formativo versa in condizioni deficitarie. Anche in questa prospettiva critica, l’articolo svolge una rassegna sulla recezione della legge: sostanzialmente positiva da parte dell’opinione pubblica, più circostanziata e criticata da parte dagli addetti ai lavori e, per ragioni diverse, dagli stessi stranieri. Si propone infine un’analisi del test di italiano, così come è stato finora somministrato, cioè sulla base del Vademecum diffuso dal  Miur, ma anche tenendo contrastivamente d’occhio le linee guida precedentemente indicate dagli Enti certificatori.     A pass for Italy. The Maroni law and the obligatory Italian test for foreigners   By law, since 2010, foreign residents in Italy who wish to appy for the “EC long term stay permit” have to demonstrate a minimal knowledge of Italian. The article covers the content of this law, considering the operative aspects and the test procedures aimed at eliciting and verifying the competence profile requested (A2 level of the QCER. Although the law demonstrates that language is a necessary cohesive factor, in line with what other European countries have already established, training in Italy is not up to par with the other countries. In this critival perspective, the article discusses the

  13. Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle

    OpenAIRE

    Silva, Heloisa Cristina [UNESP; Prette, Nancy [UNESP; Lopes, Welber Daniel Zanetti [UNESP; Sakamoto, Cláudio Alessandro M; Buzzulini, Carolina; Dos Santos, Thais Rabelo [UNESP; Cruz,Breno Cayeiro; Teixeira, Weslen F Pires [UNESP; Felippelli, Gustavo [UNESP; Carvalho, Rafael Silveira; Maciel,Willian Giquelin; Soares,Vando Edésio; da Costa, Alvimar José

    2015-01-01

    The present work aimed to evaluate, through ten different studies, the therapeutic efficacy of a new pour-on formulation, containing 1.5 per cent ivermectin +0.5 per cent abamectin, against parasites of cattle. Results obtained on trials against Rhipicephalus (Boophilus) microplus showed that the pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained superior efficacy indexes against this ectoparasite, when compared with formulations containing 0.5 per cent ivermectin...

  14. DEVELOPMENT AND CORRELATION AMONG LIPPIZANER FOALS PER LINES

    Directory of Open Access Journals (Sweden)

    T. Rastija

    2002-06-01

    Full Text Available The investigations were conducted on 114 Lippizaner breed foals in Đakovo stud. The accomplished measures obtained by cattle tape after parturition and ablactation (aged six months referred to withers height, chest girth and cannon bone circumference per fathers' line. The foals dominance per lines varied as follows: line Favory 2, Maestoso 21, Neopolitano 5, Conversano 11, Pluto 40, Siglavy 9 and Tulipan 26 foals. The measuring values were processed by the statistical program SPSS/PC (Nie et al. 1975. Statistical processing was followed by correlation computation between aforesaid measures after parturition and ablactation in the total number of foals per line. Also, statistical significance between obtained values was also calculated. The smallest parturition withers height turned to be in the foals of the line Neapolitano 100.80 cm and the greatest one in the line Siglavy 108.11 cm. The smallest chest girth was with Maestoso line foals 80.19 cm and the largest one with Siglavy 86.78 cm. However, the smallest cannon bone circumference was found to be in Neapolitano line foals 11.10 cm and the largest one with the line Favory 12.50 cm. In the post ablactation period withers height ranged from 135.50 cm in the line Favory to 143.33 cm in Siglavy line whereas chest girth was from 133.00 cm in Favory line to 142.78 cm in Siglavy line. The smallest cannon bone circumference was also with Favory line foals 16.25 cm and the largest one with Conversano line 17.23 cm. Statistical significance of all three measures was more pronounced after parturition compared to the post ablactation period. Correlation for the total number ranged from r = -0.121 to r = 0.913. Correlation among the processed body measures ranged from very strong negative to complete positive. Stronger correlation with all the lines appeared to be between withers height, chest girth and cannon bone circumference.

  15. Energy System Analysis of 100 Per cent Renewable Energy Systems

    DEFF Research Database (Denmark)

    Lund, Henrik; Mathiesen, Brian Vad

    2007-01-01

    This paper presents the methodology and results of the overall energy system analysis of a 100 per cent renewable energy system. The input for the systems is the result of a project of the Danish Association of Engineers, in which 1600 participants during more than 40 seminars discussed...... and designed a model for the future energy system of Denmark, putting emphasis on energy efficiency, CO2 reduction, and industrial development. The energy system analysis methodology includes hour by hour computer simulations leading to the design of flexible energy systems with the ability to balance...... of farming areas, or mostly on wind power, which will involve a large share of hydrogen or similar energy carriers leading to certain inefficiencies in the system design....

  16. Disseny d'una sala polivalent per una societat musical

    OpenAIRE

    TORRES SALORT, JOSEP

    2015-01-01

    Disseny d’una sala polivalent per una societat musical atenent als parà- metres acústics que defineixen la qualitat acústica d’una sala d’aquestes característiques i a la màxima polivalència en el seu ús. Extracció d’uns pautes de disseny a partir de l’anàlisi de diferents sales de reduïdes dimensions i posterior creació d’un model de sala ideal. Simulació acústica i valoració de la sala inicial. Finalment, aplicació del prototip i les millores pertinents a la sala objecte d...

  17. There is no gap 'per se' between theory and practice

    DEFF Research Database (Denmark)

    Larsen, Kristian; Adamsen, Lis; Bjerregaard, Lene Berit Skov

    2003-01-01

    and practitioners in terms of the source of their knowledge. Unlike a dominant barrier paradigm, theory and practice have different logics; they are not on a continuum nor are they hierarchically ordered. They exist in their own right as theoretical knowledge and practical knowledge. In daily practice, clinical...... nurses are inspired and learn from the context, including each other, and they are active producers of knowledge, not simply recipients of knowledge. This study, therefore, claims that there is no research-practice gap “in itself” (per se) as argued in the “barriers paradigm.”......The aim of this article is to highlight relations between theory and practice and the genesis of professional action in clinical nursing and among researchers. With use of a sociologically based empirical approach, focus is placed on the knowledge involved in the work of researchers...

  18. Malvaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Magda Chanco

    2013-10-01

    Full Text Available La familia Malvaceae es reconocida en el Perú con 38 géneros y 264 especies (Brako & Zarucchi 1993, Ulloa et al. 2004, mayormente arbustos y hierbas. En este trabajo reconocemos 87 especies endémicas en 16 géneros. El género más rico en especies endémicas es Nototriche. Las especies endémicas se encuentran en varias regiones ecológicas, entre ellas Altoandina, Mesoandina y Puna Húmeda y Seca, por encima de los 2500 m, hasta alcanzar los límites de la vegetación a 5100 m de altitud. Se aplicaron las categorías y criterios de la UICN a 84 especies. Once especies endémicas se encuentran presentes en el Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  19. Online-FLIM at 10 images per second

    Science.gov (United States)

    Becker, Wolfgang; Smietana, Stefan

    2017-02-01

    We report on a technique that records and displays fluorescence lifetime images at a rate of 10 images per second. Data acquisition is based on multi-dimensional TCSPC in combination with confocal or two-photon laser scanning. The image are calculated from the TCSPC FLIM data via the first moment of the decay data in the pixels of the images. The first-moment technique combines near-ideal photon efficiency with calculation times shorter than the frame times of the commonly used galvanometer scanners. The image rate is thus not slowed down by the lifetime calculation process. Potential applications are clinical FLIM, where suspicious areas can be identified for subsequent high-accuracy imaging, and standard FLIM microscopy, where the technique it helps the user select interesting cells in a large field of view for detailed analysis.

  20. Networks as integrated in research methodologies in PER

    DEFF Research Database (Denmark)

    Bruun, Jesper

    2016-01-01

    In recent years a number of researchers within the PER community have started using network analysis as a new methodology to extend our understanding of teaching and learning physics by viewing these as complex systems. In this paper, I give examples of social, cognitive, and action mapping...... networks and how they can be analyzed. In so doing I show how a network can be methodologically described as a set of relations between a set of entities, and how a network can be characterized and analyzed as a mathematical object. Then, as an illustrative example, I discuss a relatively new example...... of using networks to create insightful maps of learning discussions. To conclude, I argue that conceptual blending is a powerful framework for constructing "mixed methods" methodologies that may integrate diverse theories and other methodologies with network methodologies....

  1. Rilievo e rappresentazione delle geometrie parametriche per l’HBIM

    Directory of Open Access Journals (Sweden)

    Leonardo Paris

    2016-06-01

    Full Text Available Nell’analisi formale di una architettura storica si possono distinguere diverse geometrie, da quelle semplici (di muri, travi, pilastri, solai ecc. a  quelle più complesse difficilmente riconducibili a geometrie regolari (a prevalente carattere scultoreo. Vi sono alcuni elementi con geometrie complesse ma comunque traducibili per mezzo di modelli matematici. Alcune forme sono poi spesso ricorrenti, apparentemente diverse, ma riconducibili a matrici comuni, che possono essere pertanto parametrizzati. L’attività di rilievo in questi casi si esplica nel rilevare non la forma nella sua complessità ma solo gli elementi parametrici, facendo poi gli opportuni riscontri tra i parametri variabili del modello elaborato in ambiente HBIM e altri modelli ricavati da point cloud. Su questo tema è stata fatta una prima sperimentazione nel rilievo della Scala Regia in Vaticano.

  2. Un approccio multidisciplinare per l’archeologia digitale

    Directory of Open Access Journals (Sweden)

    Rodolfo Maria Strollo

    2017-12-01

    Full Text Available Obiettivo del contributo è quello di indagare le potenzialità offerte da una metodologia multidisciplinare volta alla creazione di un database digitale facilmente interrogabile, sempre disponibile e scientificamente valido da impiegare per le diverse finalità legate al patrimonio culturale immobile (ricerca scientifica, interventi di manutenzione e restauro, valorizzazione culturale, promozione turistica. La banca dati è composta da modelli infografici elaborati con riferimento a rilievi tridimensionali affidabili dal punto di vista metrico e cromatico e rappresentativi di una realtà virtuale ‘aumentata’ delle informazioni storiche, iconografico-documentali e archivistiche riferite al bene. Caso studio su cui è stato sperimentato tale approccio metodologico è l’area archeologica di Tuscolo, sui Colli Albani a sud di Roma.

  3. Moraceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Pamela Cáceres

    2013-10-01

    Full Text Available La familia Moraceae es reconocida en el Perú por presentar 19 géneros y 128 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, la mayoría arbóreas y/o hemiepífitos. En este trabajo reconocemos dos especies endémicas en igual número de géneros. Las especies endémicas se encuentran en la región Bosques Húmedos Amazónicos, entre los 115 y 220 m de altitud. Ambas especies endémicas se encuentran dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  4. Liliaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Liliaceae es reconocida en el Perú con 15 géneros (excepto Alstroemeria y Bomarea y aproximadamente 29 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, todas ellas hierbas. Esta familia incluye tres géneros endémicos, Diamena, Diora y Trichlora. En este trabajo reconocemos 11 especies endémicas en cinco géneros. Se asignó las categorías de amenaza de la UICN a seis especies. La mitad de los endemismos es conocido solamente de una localidad. Los taxones endémicos ocupan las regiones del Desierto Semicálido Costero y Mesoandina, entre los 600 y 3600 m de altitud. Solamente una especie está representada en un área natural protegida.

  5. Metodi matematici per la teoria dell’evoluzione

    CERN Document Server

    Bazzani, Armando; Freguglia, Paolo

    2011-01-01

    Esistono ormai da tempo molti articoli, in particolar modo su riviste di biomatematica, di (bio)fisica e di biologia, che presentano proposte e risultati di modellistica matematica relativi direttamente ed indirettamente alla teoria dell’evoluzione. Sicuramente questi studi sono da considerarsi cruciali per l’istituzione della biologia teorica. I temi da prendere in esame sono dapprima le convinzioni che i biologi hanno in merito. Quindi un’analisi dei precedenti tentativi di formulare una teoria matematica dell’evoluzione, nonché i relativi sviluppi e insuccessi a cui abbiamo assistito nell’ambito della "teoria della complessità". La nostra proposta consiste dunque nel realizzare una teoria matematicamente formulata e biologicamente ben fondata dell’evoluzione con specifico e giustificato riferimento a quella fenotipica. Quindi su questa base costruiamo sia di un modello geometrico sia un modello dinamico stocastico. In questo modo, pur tenendo presente l’intrinseca insufficienza dell’appro...

  6. Responsabilidad social empresarial en el Perú

    Directory of Open Access Journals (Sweden)

    Manuel Porro Rivadeneira

    2008-06-01

    Full Text Available Como parte del crecimiento y el desarrollo de los agentes económicos se ha creído conveniente analizar una institución de reciente data que afecta de modo especial a los grupos de interés (stakeholders unidos a la empresa, es por ello que la presente investigación pretende analizar de modo amplio y general los aspectos más relevantes de la Responsabilidad Social Empresarial así como aquellos de difícil tratamiento y de modo específico resolveremos la pregunta ¿cómo ha avanzado en materia de instrumentalización y normatividad la Responsabilidad Social Empresarial en el Perú?

  7. Per-oral endoscopic myotomy (POEM) for esophageal achalasia.

    Science.gov (United States)

    Pescarus, Radu; Shlomovitz, Eran; Swanstrom, Lee L

    2014-01-01

    Per-oral endoscopic myotomy (POEM) is a new minimally invasive endoscopic treatment for achalasia. Since the first modern human cases were published in 2008, around 2,000 cases have been performed worldwide. This technique requires advanced endoscopic skills and a learning curve of at least 20 cases. POEM is highly successful with over 90 % improvement in dysphagia while offering patients the advantage of a low impact endoscopic access. The main long-term complication is gastroesophageal reflux (GER) with an estimated incidence of 35 %, similar to the incidence of GER post-laparoscopic Heller with fundoplication. Although POEM represents a paradigm shift in the treatment of achalasia, more long-term data are clearly needed to further define its role in the treatment algorithm of this rare disease.

  8. Multiuser switched diversity scheduling systems with per-user threshold

    KAUST Repository

    Nam, Haewoon

    2010-05-01

    A multiuser switched diversity scheduling scheme with per-user feedback threshold is proposed and analyzed in this paper. The conventional multiuser switched diversity scheduling scheme uses a single feedback threshold for every user, where the threshold is a function of the average signal-to-noise ratios (SNRs) of the users as well as the number of users involved in the scheduling process. The proposed scheme, however, constructs a sequence of feedback thresholds instead of a single feedback threshold such that each user compares its channel quality with the corresponding feedback threshold in the sequence. Numerical and simulation results show that thanks to the flexibility of threshold selection, where a potentially different threshold can be used for each user, the proposed scheme provides a higher system capacity than that for the conventional scheme. © 2006 IEEE.

  9. The time of infection of apples by Botrytis cinerea Pers.

    Directory of Open Access Journals (Sweden)

    Hanna Bryk

    2013-12-01

    Full Text Available The time of infection of apple fruits by Botrytis cinerea Pers. was studied. Artificial inoculations with conidial suspensions of B. cinerea were done at different stages of fruit developmment (flowers, sets, fruits. In autumn the apples were harvested and stored at a temperature of 2°C for 4 months after which rotting caused by B. cinerea was evaluated. B. cinerea presence in the calyx of apples was checked throughout the growing season. This was done by plating flowers, apple and set calyces on PDA medium. Latent infection of apples by B. cinerea was found. The infection took place in the orchard and the pathogen survived latently in the calyx; disease symptoms appeared in storage. Infection is possible during the whole vegetative season, but the most important time is flowering and just before or just after harvest of apples.

  10. Sviluppo e crisi. Per una prospettiva della compresenza

    Directory of Open Access Journals (Sweden)

    Andrea Pirni

    2011-02-01

    Full Text Available Il paradigma della modernità, adottando il concetto di sviluppo come tema chiave, ha elaborato moltissime teorie del mutamento: qui sviluppo e crisi risultano necessariamente contrapposti sia sotto il profilo teorico che empirico. La complessità crescente delle società europee contemporanee mette in discussione la capacità interpretativa del mutamento che le coinvolge attualmente e suggerisce l’elaborazione di nuove prospettive che focalizzino il processo di trasformazione in corso piuttosto che soffermarsi sul risultato. Dopo aver sinteticamente inquadrato il concetto di sviluppo nell’ambito del paradigma della modernità l’articolo intende sostenere l’utilità di una prospettiva che considera congiuntamente crisi e sviluppo per analizzare il mutamento delle democrazie contemporanee.

  11. Compression phase study of the HiPER baseline target

    Energy Technology Data Exchange (ETDEWEB)

    Ribeyre, X; Nicolai, Ph; Schurtz, G; Olazabal-Loume, M; Breil, J; Maire, P H; Feugeas, J L; Hallo, L; Tikhonchuk, V T [Centre Lasers Intenses et Applications, Universite Bordeaux 1, CNRS, CEA, Universite Bordeaux 1, 351, cours de la Liberation, 33405 Talence (France)

    2008-02-15

    The European High Power laser Energy Research (HiPER) project aims at demonstrating the feasibility of high gain inertial confinement fusion using the fast ignitor approach. A baseline target has been recently developed by Atzeni et al (2007 Phys. Plasmas 14 052702). We study here the robustness of this target during the compression phase and define pulse shape tolerances for a successful fuel assembly. The comparison between a standard and a relaxation pulse shows that the latter allows one to reduce both the laser power contrast and the growth of perturbations due to Rayleigh-Taylor instability. We have found that with 95 kJ of absorbed laser energy one can assemble the fuel with a peak density around 500 g cm{sup -2} and a peak areal density of 1.2 g cm{sup -2}. This implies a total target gain of about 60.

  12. Numerical simulations of the HiPER baseline target

    Energy Technology Data Exchange (ETDEWEB)

    Ribeyre, X.; Nicolai, Ph.; Schurtz, G.; Olazabal-Loume, M.; Breil, J.; Maire, P.H.; Feugeas, J.M.; Hallo, L.; Tikhonchuk, V.T. [Bordeaux-1 Univ., Centre Lasers Intenses et Applications, CNRS, CEA, 33 - Talence (France)

    2009-08-15

    The European High Power laser Energy Research (HiPER) project aims at demonstrating the feasibility of high gain inertial confinement fusion using the fast ignitor approach. A baseline target has been recently developed by Atzeni et al. [Phys. Plasmas 14, 052702 (2007)]. The radiative transport have a minor effect on the peak areal density but decreased by 20% the peak density. We have found that with 95 kJ of absorbed laser energy one can assemble the fuel with a peak density around 500 g/cm{sup 3} and a peak areal density of 1.2 g/cm{sup 2}. This implies a total target gain of about 60. (authors)

  13. Numerical simulations of the HiPER baseline target

    Energy Technology Data Exchange (ETDEWEB)

    Ribeyre, X; Nicolai, P; Schurtz, G; Olazabal-Loume, M; Breil, J; Maire, P H; Feugeas, J L; Hallo, L; Tikhonchuk, V T [Centre Lasers Intenses et Applications, Universite Bordeaux 1, CNRS, CEA, Universite Bordeaux 1, 351, cours de la Liberation, 33405 Talence (France)], E-mail: ribeyre@celia.u-bordeaux1

    2008-05-15

    The European High Power laser Energy Research (HiPER) project aims at demonstrating the feasibility of high gain inertial confinement fusion (ICF) using the fast ignitor approach. A baseline target has been recently developed by Atzeni et al. [Phys. Plasmas 14, 052702 (2007)]. The comparison between a standard and a relaxation pulse shows that the latter one allows to reduce both the laser power contrast and the growth of perturbation under Rayleigh-Taylor instability. We have found that with 95 kJ of absorbed laser energy one can assemble the fuel with to a peak density around 500 g/cm{sup 3} and to a peak areal density of 1.2 g/cm{sup 2}. This implies a total target gain of about 55.

  14. Percorsi di apprendimento per gli stranieri nella scuola italiana

    Directory of Open Access Journals (Sweden)

    Laura Sala

    2009-12-01

    Full Text Available Normal 0 14 MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabella normale"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman";} Nell’articolo si passano in rassegna le nuove proposte editoriali per gli studenti non italofoni nella scuola secondaria di primo grado e di uno in particolare, a titolo esemplificativo, si analizzano più da vicino le caratteristiche. L’indagine considera le strategie di scrittura controllata messe in atto nei testi. Infatti, tutti questi manuali (antologie, grammatiche, libri di storia sono realizzati secondo un’idea comune: le difficoltà poste dall’italiano per lo studio agli stranieri devono essere appianate attraverso la semplificazione: per quanto riguarda le discipline scolastiche facilitare l’apprendimento significa soprattutto semplificare i testi per fornire conoscenze e nozioni fondamentali e competenze e abilità di base da cui sia possibile poi accedere a livelli più alti e raffinati. Si sottolinea, dunque, che  la versione semplificata dei testi dei manuali disciplinari deve essere intesa come strumento propedeutico, transitorio, che aiuta l’apprendente a compiere i primi passi nello sviluppo delle abilità di studio sia orali che scritte da cui procedere verso competenze linguistico-cognitive più ambiziose.  Normal 0 14 MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabella normale"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman";} In this paper an overview is given of the new

  15. Dilleniaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Dilleniaceae es una adición reciente a la flora endémica peruana; los endemismos han sido recolectados y reconocidos hacia fines de los 1990. Está representada en el Perú por seis géneros y 23 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, la mayoría lianas. En este trabajo reconocemos tres endemismos en dos géneros. Las especies endémicas ocupan la región Bosques Húmedos Amazónicos, entre los 100 y 125 m de altitud. No se encuentra representada en el Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  16. Onagraceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Susy Castillo

    2013-10-01

    Full Text Available Esta es la familia de las «fucsias», la cual es reconocida en el Perú por presentar seis géneros y 76 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, principalmente arbustos y hierbas. En este trabajo reconocemos 24 especies endémicas, la mayoría en el género Fuchsia. Las especies endémicas se encuentran mayormente en la región Bosques Muy Húmedos Montanos, entre los 1600 y 2500 m de altitud. Diez especies endémicas se encuentran representados dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  17. Crassulaceae endémicas del Perú

    Directory of Open Access Journals (Sweden)

    Blanca León

    2013-10-01

    Full Text Available La familia Crassulaceae es reconocida en el Perú por presentar cinco géneros y 29 especies (Brako & Zarucchi, 1993, mayormente arbustos y hierbas. En este trabajo reconocemos 13 especies y dos variedades como endemismos peruanos en tres géneros. Echeveria es el género con el mayor número de especies endémicas. Los taxones endémicos ocupan principalmente las regiones Mesoandina y Puna Húmeda y Seca, entre los 1700 y 4500 m de altitud. Se aplicaron las categorías y criterios de la UICN a nueve taxones. Dos Crassulaceae endémicas están representados dentro del Sistema Nacional de Áreas Naturales Protegidas por el Estado.

  18. Husserl and Kant on Persönlichkeit

    Directory of Open Access Journals (Sweden)

    James Dodd

    2011-03-01

    Full Text Available This paper pursues a Kantian critique of Husserl’s theory of moral consciousness as it is found in his lectures on ethics and other shorter pieces on political and moral philosophy from the interwar period. The critique centers on Kant’s conception of moral personality (Persönlichkeit, arguing that Husserl fails to appreciate the force of this idea, subsequently leaving himself open to the charge of moral perfectionism. The paper ends with a positive assessment of Husserl’s thought, however, arguing that Husserl provides important resources for understanding moral consciousness as a sensibility for the possible, adding an important dimension to approaches in ethics that tend to center exclusively on questions of motivation and principle.   

  19. The evolution of per-cell organelle number

    Directory of Open Access Journals (Sweden)

    Logan W. Cole

    2016-08-01

    Full Text Available Organelles with their own distinct genomes, such as plastids and mitochondria, are found in most eukaryotic cells. As these organelles and their host cells have evolved, the partitioning of metabolic processes and the encoding of interacting gene products have created an obligate codependence. This relationship has played a role in shaping the number of organelles in cells through evolution. Factors such as stochastic evolutionary forces acting on genes involved in organelle biogenesis, organelle-nuclear gene interactions, and physical limitations may, to varying degrees, dictate the selective constraint that per-cell organelle number is under. In particular, coordination between nuclear and organellar gene expression may be important in maintaining gene product stoichiometry, which may have a significant role in constraining the evolution of this trait.

  20. Michail Bachtin, Su Flaubert. Per una stilistica del romanzo

    Directory of Open Access Journals (Sweden)

    Stefania Sini

    2011-12-01

    Full Text Available Presentiamo in traduzione italiana due testi di Bachtin redatti intorno agli anni 1944-1945 quali appunti preparatori a un lavoro su Gustave Flaubert. Da queste pagine lo scrittore francese mostra di rappresentare per il pensatore russo una figura molto più importante di quanto si supponesse finora. Fra i tanti motivi di estremo interesse qui presenti segnaliamo la riflessione sul ruolo degli animali in letteratura in riferimento al tema flaubertiano della bêtise – con aperture teoriche che troveranno ampie conferme negli studi letterari degli anni più recenti – e, ad essa legato, l’insistito richiamo sulla «possibilità di una visione del mondo completamente diversa», che ammetta la «curvatura» dello spazio e del tempo, quale presupposto della parola romanzesca.

  1. Responsabilidad social empresarial en el Perú

    Directory of Open Access Journals (Sweden)

    Manuel Porro Rivadeneira

    2008-07-01

    Full Text Available Como parte del crecimiento y el desarrollo de los agentes económicos se ha creído conveniente analizar una institución de reciente data que afecta de modo especial a los grupos de interés (stakeholders unidos a la empresa, es por ello que la presente investigación pretende analizar de modo amplio y general los aspectos más relevantes de la Responsabilidad Social Empresarial así como aquellos de difícil tratamiento y de modo específico resolveremos la pregunta ¿cómo ha avanzado en materia de instrumentalización y normatividad la Responsabilidad Social Empresarial en el Perú?

  2. Alstroemeriaceae endémicas del Perú

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    Blanca León

    2013-10-01

    Full Text Available La familia Alstroemeriaceae es reconocida en el Perú con dos géneros, Alstroemeria y Bomarea, y 85 especies (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004, básicamente hierbas y enredaderas. En este trabajo reconocemos 22 endemismos en el género Bomarea. Estos taxones endémicos ocupan varias regiones ecológicas, incluyendo la del Bosque Húmedo Montano y de la Puna Seca y Húmeda, entre los 1000 y 4600 m de altitud. Aproximadamente un tercio de esas especies, son conocidas solamente de sus localidades tipo, ubicadas en cadenas montañosas aisladas o en cuencas que han recibido escasa herborización los últimos 80 años, como la del Monzón. Nueve de estas especies están representadas en áreas naturales protegidas.

  3. Michel de Montaigne. Per una lettura degli Essais

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    Giovanni Bottiroli

    2012-12-01

    Full Text Available Si riflette sullo stile di pensiero degli Essais, in cui, come afferma lo stesso Montaigne «vi è gran libertà di parlare in ogni senso, e pro e contro». Si rileva la capacità del pensatore di conferire un nuovo significato a termini tradizionali, recuperati in accezioni inedite. Emerge per esempio una nozione di forma che sa includere il molteplice senza irrigidirlo nell‟Uno. Ciò che Montaigne ri-fiuta è la concezione tradizionale di forma come essenza rigida, come insieme di tratti o di proprietà; l‟identità del soggetto umano – l‟ humaine condition – è invece una condizione flessibile, cioè aperta a destini divergenti. Il pensiero di Montaigne si può interpretare dunque come un pensiero della flessibilità.

  4. Delivering phage therapy per os: benefits and barriers.

    Science.gov (United States)

    Zelasko, Susan; Gorski, Andrzej; Dabrowska, Krystyna

    2017-02-01

    Multidrug-resistant bacterial infections of the gastrointestinal tract pose a serious public health concern. High levels of antibiotic drug resistance, along with the potential for antibiotics to precipitate disease or alter the gut microbiome has prompted research into alternative treatment methods. Evidence suggests that bacteriophage therapy delivered per os may be well-suited to target such infections. Areas covered: Herein, we discuss the specific advantages and challenges of using orally administered phage therapy. Our literature review encompasses recent works using phages to target various clinically-relevant bacteria in vivo. We also provide insights into methods that aim to overcome the barriers to effective phage transit through the harsh gastrointestinal environment. Expert commentary: Evidence from a number of in vivo animal studies suggests that targeting bacterial infections using phages delivered orally holds potential. Efficacious oral phage therapy depends on the delivery of sufficient phage titers to the infection site, which may be hindered by the host's gastrointestinal tract and immune response.

  5. La democracia en el Perú: una terca voluntad

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    Carolina ROMERO

    2009-11-01

    Full Text Available RESUMEN: La construcción de la democracia en el Perú es una vieja tarea que se realiza, aunque imperceptiblemente, lenta y tercamente tanto en la cultura política de los nuevos ciudadanos como en la organización política de la sociedad. El presente artículo es un ensayo sobre la aventura democrática en el primer lustro del siglo XXI yendo a las últimas décadas del siglo XX en el Perú, en las que la institucionalidad democrática adquiere nueva legitimidad, para entender las dificultades que los actores políticos encuentran y que se deben tomar en cuenta para hablar de la calidad de la democracia, en la línea que el artículo de Levine y Molina (2007 nos propone.ABSTRACT: The construction of democracy in Peru is a long standing challenge that has advanced slowly and stubbornly, if imperceptibly at time, in both the political culture of the citizens and the political organization of society. This article analyzes the «democratic adventure» in Peru in the first years of the 21st century in the context of the last two decades of the 20th, when democratic institutionalization achieved a new level of legitimacy, to identify the challenges to democracy that political actors have confronted. These elements will help analyze the quality of democracy along the lines proposed in the work of Levine and Molina (2007.

  6. El Perú y las falacias del "neopopulismo"

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    Aldo Olano Alori

    2006-01-01

    Full Text Available En este artículo, Aldo Olano plantea que el Perú contemporáneo hay que entenderlo como producto de circunstancias en donde confluyen aspectos de tipo histórico como también políticos, diversos modelos de desarrollo como también evidentes cambios producidos dentro de la sociedad. La idea central de este trabajo es aquella que nos indica que la ingobernabilidad recurrente es producto de un tipo de cultura política anti-institucional, pero no necesariamente anti-estatal. Se argumenta que esta situación es producto del mantenimiento de unos órdenes sociales y políticos excluyentes, a pesar de los proyectos modernizantes de corte ya sea liberal o proteccionista puestos en marcha a lo largo del siglo pasado. De la misma manera cuestiona algunos de los paradigmas con los cuales se adelantaron importantes estudios sobre el “desarrollo” político tenido por el país en las últimas décadas, por lo tanto establece que el Perú actual sería la expresión paradigmática de un desencuentro entre lo ideológico - social y lo político – institucional. En tal sentido, el estado de ingobernabilidad y preeminencia de prácticas populistas es producto de la confluencia de tres proyectos considerados en sí mismos como inconclusos: el reformismo del gobierno militar (1968-1975, el demócrata liberal (1980-1990, 2000-2006 y el autoritarismo patrimonialista (1992-2000

  7. Per-anal excision of large, rectal, villous adenomas.

    Science.gov (United States)

    Featherstone, J M; Grabham, J A; Fozard, J B

    2004-01-01

    Considering the malignant potential of villous adenoma of the rectum, complete resection at the first intervention is desirable and yet many series suggest that a high recurrence rate must be expected. The experience of one colorectal surgeon in the management of this condition is described. Between 1993 and 2000, 50 patients underwent per-anal resection of villous adenoma. The procedure was conducted in the prone jackknife position unless contraindicated, with dissection performed using a diathermy blade, with particular attention to circumferential and deep margins of excision. The mean distance of the proximal margin of the tumor from the dentate line was 5.6 (range, 0.5-11) cm. The mean length of the tumor was 5.2 (range, 0.5-9) cm. Mean anesthetic time was 27 (range, 10-110) minutes, and median hospital stay was two (range, 1-14) days. There was no significant perioperative morbidity and no mortality. On histology of ten patients, there were foci of adenocarcinoma. Excision was complete histologically in 49 patients. The median follow-up was 30 (range, 6-91) months. The patient with incomplete excision developed a probable recurrence after six months, which was ablated with diathermy (residual tumor rate, 2.1 percent). Two patients have subsequently developed villous adenoma at different sites within the rectum (metachronous tumor rate, 4.3 percent). Many series of this procedure report recurrence in up to 36 percent and significant complication in up to 19 percent of patients. Transanal endoscopic microsurgery has achieved recurrence rates of 2.8 percent and low complication rates but for economic reasons has failed to find a widespread role. This article demonstrates that large, villous tumors of the low and mid rectum can be simply and effectively treated by per-anal resection with recurrence rates equivalent to transanal endoscopic microsurgery.

  8. Download this PDF file

    African Journals Online (AJOL)

    appropriate for the 7-oxo form and the revision, on the basis of spectroscopic data, of the structure of praecarisone. A to 7-oxo-9-methoxy chalcone (2) has been published (3). In a recent investigation (4) of the seed-pods of Tephrosia pumild (Lam.) Pers. we reported the occurrence of praecansome A as the major flavonoid.

  9. Le tecniche AMS e IBA del CEDAD per lo studio dei Beni Culturali, Ambientali e per la Scienza dei Materiali

    Directory of Open Access Journals (Sweden)

    Lucio Calcagnile

    2011-09-01

    Full Text Available ItGli acceleratori di particelle sono diventati un potente strumento per la diagnostica dei materiali in molti campi di ricerca. Questo articolo descrive la facility AMS-IBA installata presso il CEDAD – Centro di Datazione e Diagnostica dell’Università del Salento e riporta alcune applicazioni in Archeologia, Scienze ambientali e Scienza dei materiali.EnParticle accelerators have become a powerful tool for the diagnostics of materials in many research fields. This paper describes the AMS-IBA (Accelerator Mass Spectrometry – Ion Beam Analysis facility installed at CEDAD-Center for Dating and Diagnostics of the University of Salento, Italy and some applications in Archaeology, Environmental Sciences and Materials Science.

  10. Urban movements and disempowerment in Perú and Venezuela Movimientos urbanos y desempoderamiento en Perú y Venezuela

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    Daniel H. LEVINE

    2010-11-01

    Full Text Available This paper addresses a core puzzle: why is continued citizen mobilization accompanied by growing disempowerment of those same citizens? Why do movements fail, leaders burn out and members disperse, and what are the implications of this organizational failure for demo¬cratic representation? Our consideration of the issues is rooted in a close examination of urban movements, mobilization, empowerment and disempowerment in the recent experience of Venezuela and Perú. The puzzle that concerns us is of course not limited to these two countries: it is common to all the Andean republics, and in different ways, to much recent experience of urban mobilization in Latin America and beyond. After a brief account of urban citizen move¬ments and politics in our two cases, we outline general reflections on the nature of empowerment and disempowerment, on the peculiar combination of strengths and weaknesses that mark many contemporary movements. A close examination of types of movements and their links with poli¬tical parties and protest follows. The character of city life is important here. We close with analysis of recent waves of urban mobilization in Perú (that sparked the ouster of president Alberto Fujimori and in Venezuela (both for and against president Hugo Chávez Frías, and with reflections on the likely future of empowerment and disempowerment for urban citizens and the implications of this perspective for democratic representationEste artículo plantea un puzzle principal: ¿por qué la movilización ciudadana continuada viene acompañada de un crecimiento del desempoderamiento de estos mismos ciudadanos? ¿Por qué los movimientos fracasan, los líderes se desgastan y los miembros se dispersan, y cuáles son las implicaciones del fracaso organizativo para la representación democrática? Nuestra consideración del asunto encuentra sus raíces en un profundo análisis de los movimientos urbanos, de la movilización, del empoderamiento y del

  11. Patologia del legame in post-modernità: quale scambio? Per quale coppia? Per quale società?

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    Virginia Maloni

    2011-06-01

    Full Text Available La post-modernità ci ha messo di fronte ad una metamorfosi di tutti i legami relazionali tra noi e l'ambiente, i codici morali, l'altro da noi ed il mondo circostante. Credo che oggi tra le varie emergenze quotidiane, si sviluppi sempre più quello che è la dipendenza affettiva, soprattutto nelle relazioni. Nelle culture tradizionali e semi-tradizionali si ha una chiara concezione dell'essere dentro o fuori da una cosa. Pensiamo per esempio al confine dell'incesto. Nelle culture tradizionali è chiarissimo dove finiscono le famiglie e dove inizia il modo esterno ai legami di sangue chiamato appunto degli affini. Questo discorso è invece molto più caotico nella post-modernità, dove troviamo un'aggressione a qualsiasi tipo di confine, limite e legame familiare.

  12. Anatomia foliar de Alpinia zerumbet (Pers. Burtt & Smith (Zingiberaceae Leaf anatomy of Alpinia zerumbet (Pers. Burtt & Smith (Zingiberaceae

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    Elaine Santiago Brilhante de Albuquerque

    2004-03-01

    Full Text Available Foi realizado o estudo da anatomia foliar de Alpinia zerumbet (Pers. Burtt & Smith, espécie da família Zingiberaceae, coletada no Horto Botânico da Quinta da Boa Vista, São Cristóvão, Rio de Janeiro, RJ. A espécie é vulgarmente conhecida como colônia, destacando-se pela beleza de suas inflorescências e pelo valor medicinal que lhe é atribuído. O presente estudo tem como objetivo fornecer dados que possam contribuir para a compreensão das características morfológicas da espécie e da taxonomia da família. Anatomicamente a folha apresenta organização dorsiventral do mesofilo, caráter não peculiar à maioria das monocotiledôneas, e pela ocorrência de células oleíferas dispersas no mesofilo e na epiderme da face abaxial. A folha é anfiestomática e apresenta hipoderme em ambas as faces.It was accomplished a study of the foliar anatomy of Alpinia zerumbet (Pers. Burtt & Smith, Zingiberaceae family collected at Horto Botânico of Quinta da Boa Vista, São Cristóvão, Rio de Janeiro, RJ. This species is vulgarly known as "colônia" and is distinguished by its beautiful inflorescence and medicinal value. The main objective of this research is to contribute to the understanding of the morphological characteristics of this species as well its family taxonomy. Anatomically, the leaf presents a dorsiventral organization of the mesophyll, disaccording with most monocotyledonous. Another remarkable aspect is the presence of scattered oil cells throughout the mesophyll and abaxial surface of the leaf. The leaf is amphistomatic and presents hypodermis on both sides.

  13. Estudio del Helicobacter pylori en el Perú

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    Alberto Ramírez Ramos

    2002-10-01

    Full Text Available El presente es el resultado del trabajo que diversos investigadores realizaron sobre la infección del H. pylori en el Perú. Epidemiología: notamos que la infección se adquiere a edades tempranas de la vida, siendo probablemente la vía oral-fecal y por el agua la forma de transmisión más importante. La prevalencia de la infección por H. pylori en los niveles socioeconómicos bajos es la misma en la costa, sierra y selva, manteniéndose estacionaria, a diferencia de los niveles medio y alto donde está disminuyendo (fenómeno asociado a la disminución de úlcera péptica y adenocarcinoma de estómago No existe evidencia que permita afirmar que ciertas razas tienen mayor predisposición para adquirir la infección, pero se ha notificado que en la población de altura es más frecuente la prevalencia de gastritis crónica atrófica que en la que habita a nivel del mar. Microbiología, biología molecular y patología: las cepas del H. pylori predominantes en el Perú son similares a las de España y Europa, pero muy diferentes a las encontradas en China y Japón. La gastritis crónica superficial, gastritis crónica profunda y gastritis crónica atrófica son diferentes estadios evolutivos de la lesión inflamatoria producida por la bacteria en el estómago. Diagnóstico: la biopsia de estómago utilizando coloración con plata es el patrón de oro. La combinación de dos métodos también puede ser útil. Tratamiento: los esquemas triples producen erradicación mayor al 80% los esquemas dobles y la monoterapia son insuficientes: la tasa de recaída postratamiento es alta y la mayoría por una cepa diferente.

  14. Per una didattica della musica del Novecento: un percorso possibile

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    Graziella Seminara

    2013-12-01

    Full Text Available Questo percorso didattico è concepito come ‘guida’ all’ascolto e all’analisi della sezione introduttiva e del primo quadro (Les augures printaniers. Danses des adolescentes del Sacre du printemps di Igor Stravinskij: l’opera stravinskiana, annoverata tra le grandi partiture del Novecento, presenta infatti caratteristiche sonore immediatamente percepibili, che consentono anche all’ascoltatore non esperto di costruire con agio una propria ‘mappa mentale’ della composizione.Il percorso si sviluppa come riflessione a vasto raggio, articolata in una serie di suggerimenti che potranno di volta in volta essere declinati in approcci didattici differenziati, calibrati sugli stadi d’età e di competenza dei discenti; al di là delle specifiche considerazioni sull’Introduction del Sacre e sugli Augures printaniers, con questo percorso si intende altresì avanzare un’ipotesi di lavoro: la pratica dell’analisi anche di poche pagine di una partitura come occasione per sviluppare un discorso di più ampia portata sugli elementi costitutivi del linguaggio musicale e sui procedimenti del comporre.Dopo l’individuazione dei parametri principali della scrittura stravinskiana – ritmo, timbro, tessitura sonora – si ricostruiscono le ragioni storiche e culturali del radicamento della partitura del Sacre nelle tradizioni folkloriche dell’Europa orientale (russa bielorussa lituana e si approfondiscono quindi taluni fondamentali stilemi del comporre di Stravinskij: dal ricorso all’ossessiva ripetitività dell’ostinato alla costruzione di percorsi formali di tipo paratattico, fondati sulla frammentazione e la discontinuità, sino al conseguimento di una nuova organizzazione del tempo musicale, sottratta alla direzionalità propria della musica di tradizione classico-romantica. Il percorso si chiude con la proposta di ulteriori possibili approfondimenti, che vanno dalla considerazione del ruolo determinante della scala ottatonica per la

  15. Italiano per Cinesi – Didael. Corso di lingua italiana online.

    Directory of Open Access Journals (Sweden)

    Franca Bosc

    2009-12-01

    Full Text Available Normal 0 14 MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabella normale"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman";} Per gli apprendenti sinofoni la lingua italiana, con la sua complessità e fragilità morfologica, rappresenta  un ostacolo notevole. Il corso  pone attenzione alla lontananza tipologica delle due lingue con schede grammaticali in cinese e, soprattutto, i livelli A1 e A2 hanno una progressione molto controllata per fissare le basi della lingua italiana. Sono disponibili un Glossario, tre diversi tipi di dizionario (il dizionario automatico, il dizionario, visuale e il dizionario fraseologico e approfondimenti culturali. Si tratta di un corso completo che consente di sviluppare le competenze previste  dal Quadro Comune Europeo; il modello formativo è flessible e prevede varie opzioni di erogazione.  Normal 0 14 MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabella normale"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman";} For Chinese speakers Italian, in all its complexity and morphological fragility, represents a great obstacle.  This course takes into careful account the distance between the two language types, with grammar fact cards in Chinese and, above all, progression at levels A1 and A2 which is very carefully controlled in order to establish the bases of the Italian language.  A Glossary, three different types of dictionary (an automatic dictionary, a visual dictionary and a dictionary of phrases

  16. Viaggiatori per “diporto” nella Napoli di antico regime

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    Paola Avallone

    2010-10-01

    Full Text Available Per il periodo preunitario siamo ancora lontani dall’idea di turismo nell’accezione attuale e ancor di più non si può parlare di turismo di massa. Operatori turistici come Thomas Cook arriveranno in Italia solo nella seconda metà dell’800 quando ormai è in declino il Grand Tour. Diffusosi a partire dal XVII, il Grand Tour era inteso come quel lungo viaggio nell'Europa continentale effettuato dai ricchi giovani dell'aristocrazia britannica e destinato a perfezionare la loro educazione con partenza ed arrivo in una medesima città. Questo viaggio poteva durare dai pochi mesi fino a 8 anni. Le destinazioni principali erano la Francia, l'Olanda, la Germania, ma aveva come obiettivo privilegiato l'Italia e Roma, e di norma includeva le tappe di Venezia, Firenze, Bologna, Pisa e Napoli. Durante il Tour, i giovani imparavano a conoscere la politica, la cultura, l'arte e le antichità dei paesi europei. Passavano il loro tempo facendo giri turistici, studiando e facendo acquisti. L'Italia con la sua eredità della Roma antica, con i suoi monumenti, divenne uno dei posti più popolari da visitare. Oltre alla conoscenza del mondo antico gli Inglesi vennero così a contatto con le opere di Palladio e con il Neoclassicismo. Napoli, soprattutto quando divenne Capitale con l’arrivo della dinastia borbonica sul trono, era tra le mete finali dei grandtouristi. Oltre alle bellezze naturali e al tepore del clima mite durante tutto l’anno, l’élite culturale europea era interessata alla storia e all’arte del sud della penisola. L’Italia meridionale raccoglieva l’eredità della Magna Grecia e le suggestioni dell’Impero Romano, che si potevano ammirare sia a est che a ovest della città. Ma c’erano anche il Vesuvio, la Solfatara, i Campi Flegrei, luoghi legati ad eventi impressionanti e scientificamente ancora non provati, e che sollecitavano la curiosità di naturalisti, studiosi di flora e fauna ma anche di pittori e artisti in generale

  17. Per-Sample Multiple Kernel Approach for Visual Concept Learning

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    Tian Yonghong

    2010-01-01

    Full Text Available Abstract Learning visual concepts from images is an important yet challenging problem in computer vision and multimedia research areas. Multiple kernel learning (MKL methods have shown great advantages in visual concept learning. As a visual concept often exhibits great appearance variance, a canonical MKL approach may not generate satisfactory results when a uniform kernel combination is applied over the input space. In this paper, we propose a per-sample multiple kernel learning (PS-MKL approach to take into account intraclass diversity for improving discrimination. PS-MKL determines sample-wise kernel weights according to kernel functions and training samples. Kernel weights as well as kernel-based classifiers are jointly learned. For efficient learning, PS-MKL employs a sample selection strategy. Extensive experiments are carried out over three benchmarking datasets of different characteristics including Caltech101, WikipediaMM, and Pascal VOC'07. PS-MKL has achieved encouraging performance, comparable to the state of the art, which has outperformed a canonical MKL.

  18. Per-Sample Multiple Kernel Approach for Visual Concept Learning

    Directory of Open Access Journals (Sweden)

    Ling-Yu Duan

    2010-01-01

    Full Text Available Learning visual concepts from images is an important yet challenging problem in computer vision and multimedia research areas. Multiple kernel learning (MKL methods have shown great advantages in visual concept learning. As a visual concept often exhibits great appearance variance, a canonical MKL approach may not generate satisfactory results when a uniform kernel combination is applied over the input space. In this paper, we propose a per-sample multiple kernel learning (PS-MKL approach to take into account intraclass diversity for improving discrimination. PS-MKL determines sample-wise kernel weights according to kernel functions and training samples. Kernel weights as well as kernel-based classifiers are jointly learned. For efficient learning, PS-MKL employs a sample selection strategy. Extensive experiments are carried out over three benchmarking datasets of different characteristics including Caltech101, WikipediaMM, and Pascal VOC'07. PS-MKL has achieved encouraging performance, comparable to the state of the art, which has outperformed a canonical MKL.

  19. Gašper Žitnik and His Books

    Directory of Open Access Journals (Sweden)

    Sonja Svoljšak

    2014-12-01

    Full Text Available Gašper Žitnik (ca. 1535–1585 was a jurist, a doctor of law from the Vienna university, a Count palatine, an Inner-Austrian government councillor and an important political figure in Carniolian and Styrian Counter-Reformation. He was also Bishop Tomaž Hren’s (1560−1630 uncle and had important influence on his upbringing, education and career. Besides being an occasional poet in his youth, he was also a book collector and he liked to inscribe various details about his study, work and personal life into his books. The paper gives an overview of Žitnik’s books, which are kept in the National and University Library, with an emphasis on his hand-written notes and some other peoples’ hand-written notes in his books which are of significance. The findings complement the already known facts about Žitnik’s life and work through this secondary information while also revealing some details about the relation between his books and him as their reader.

  20. Perú, después de las elecciones

    Directory of Open Access Journals (Sweden)

    Luis PÁSARA

    2009-11-01

    Full Text Available RESUMEN: En este artículo se reflexiona sobre la elección presidencial peruana a partir de los resultados electorales de la primera y la segunda vuelta electoral. El autor sostiene que la elección de Alejandro Toledo no supone una recuperación del país y expone las características de los comicios en los que participó la mitad de la población. Asimismo, analiza el perfil del nuevo elector peruano «el cholo» y lo señala como el nuevo protagonista social del Perú; reflexiona respecto a la salida de Fujimori y Montesinos del poder y puntualiza el papel de Estados Unidos en la caída del régimen fujimorista.ABSTRACT: This article analyzes the Peruvian presidential election taking as a point of departure the electoral results of the first and second rounds. The author argues that the election of Alejandro Toledo does not imply a recovery of the country and he presents the characteristics of the electoral contest in which half of the population participated. He also analyzes the profile of the new Peruvian voter, the «cholo», and points to them as new social protagonists in Peru. The author reflects on the exit from power of Fujimori and Montesinos, specifying the role of the United States in the fall of the Fujimori regime.

  1. Per una didattica del melodramma. Idee e percorsi

    Directory of Open Access Journals (Sweden)

    Giorgio Pagannone

    2011-04-01

    Full Text Available Il presente intervento ha lo scopo di mettere a fuoco alcune questioni di fondo sulla didattica del melodramma e di formulare alcune ipotesi metodologiche approfondite nel volume Insegnare il melodramma: saperi essenziali, proposte didattiche, finanziato dall’Università della Valle d’Aosta e destinato ad insegnanti della scuola di base, dalla scuola dell’infanzia alla secondaria superiore. Il libro è suddiviso in due parti: la prima di riflessione teorica e metodologica; la seconda più operativa, e contenente alcuni percorsi didattici divisi per fasce scolastiche. Esso dunque intende fornire a chi opera nella scuola una riflessione articolata e almeno un po’ approfondita sull’opera lirica, e nel contempo degli strumenti di lavoro concreti. Si può constatare infatti che alcune recenti pubblicazioni sulla didattica dell’opera puntano sull’immediata operatività (anche ai livelli più precoci d’istruzione, ma difettano, a nostro avviso, di un’adeguata cornice teorico-metodologico-concettuale: il che si ripercuote anche sul livello e sulla qualità dei percorsi didattici stessi.

  2. Cisticercosis diseminada: reporte de un caso en Perú

    Directory of Open Access Journals (Sweden)

    Julio Maquera-Afaray

    Full Text Available La cisticercosis es una enfermedad desatendida y endémica en el Perú que afecta comúnmente al sistema nervioso central (SNC, causando la neurocisticercosis (NCC. Sin embargo, son pocos los reportes de cisticercosis diseminada (CCD en el mundo. Se reporta el caso de un paciente varón de 82 años, natural del departamento de Junín, que presenta pérdida brusca del nivel de conciencia asociada a convulsiones tónico-clónicas generalizadas. La tomografía axial computarizada y la resonancia magnética nuclear cerebral mostraron múltiples lesiones de aspecto quístico con presencia de escólex en su interior y compatibles con NCC masiva; la resonancia magnética nuclear torácica, abdominal y pélvica permitieron evidenciar la diseminación multiorgánica de cisticercos. Aunque es poca la casuística y experiencia terapéutica en los casos de CCD, el paciente recibió tratamiento antiparasitario con albendazol y corticoides, logrando una evolución clínica favorable y sin complicaciones durante la hospitalización

  3. Strategie robotiche ed informatiche per la fruizione museale

    Directory of Open Access Journals (Sweden)

    Michela Cigola

    2014-04-01

    Full Text Available ITL’articolo intende presentare una ricerca multidisciplinare in corso presso l’Università di Cassino. Il progetto si incentra sull’uso di robot per effettuare una visita ad un museo durante l’orario di chiusura, permettendo al visitatore, connesso al robot attraverso il proprio computer di casa o il proprio tablet o smartphone, di controllare e “guidare” il dispositivo attraverso le sale del museo, inquadrando e guardando le varie opere, ottenendone o una semplice visione oppure una esplorazione ampliata dell’opera che si sta osservando, attraverso un database multimediale appositamente predisposto.ENThe article intends to present a multidisciplinary research underway at the University of Cassino. The project focuses on the use of robots to make a visit to a museum during the hours of closure.  The visitor, connected to the robot through computer or tablet or smartphone, will be able to check and "ride" the device through the Museum obtaining or a simple vision or an extended exploration of the museum through a specially designed multimedia database.

  4. Tre voci per un Lexicon di Giuseppe Pontiggia

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    Daniela Marcheschi

    2014-07-01

    Full Text Available Tre parole-chiave offrono lo spunto per un’immersione nel pensiero e nell’opera di Giuseppe Pontiggia. La prima: parola, riaffermata dallo scrittore in quanto atto civile e ‘corporeo’ mediante il quale l’uomo fa esperienza di se stesso entrando in contatto con i suoi simili e con il circostante, ricongiungendosi insieme alla sua più profonda e antica natura. Viene così restituita allo scrittore/critico la responsabilità di lottare contro l’attuale minaccia dello svuotamento linguistico, nel nome di una costruttiva utopia culturale. La seconda parola, musica, serve a illuminare i romanzi di Pontiggia – in specie La grande sera e L’arte della fuga – attraverso suggestive analogie con la musica classica e il jazz, predilette dallo scrittore. Ossimoro è l’ultima voce di questo Lexicon: figura retorica, ma soprattutto figura conoscitiva che permette allo scrittore di scoprire la propria verità e il proprio linguaggio e al lettore di abbracciare una visione non lineare e problematica del mondo, capace di ampliare le prospettive e rinnovare lo sguardo.

  5. Perú 1985. Rescate de la memoria colectiva

    Directory of Open Access Journals (Sweden)

    María Teresa Quiroz

    2015-01-01

    Full Text Available La revista se centra en el rol que desempeñan los medios en las campañas electorales,se publica la función política de éstos en Escandinavia,(1983La campaña electoral en una transición política en Argentina, (1986Una democracia amenazada en Costa Rica, (1985 Rescate de la memoria colectiva desde el Perú, (1983 Impacto de la crisis económica en Venezuela,(1986 Impresiones del periodismo político en Austria, (1984Propaganda electoral en la prensa de Quito, (1984 Estados Unidos. Estrategia de Comunicación:la elección presidencial. En la sección NUEVAS TECNOLOGÍAS se habla de los flujos de datos transfrontera (FDT y cuestiones afines. En DOCUMENTOS se publica sobre Innovación tecnológica en Educación, el Informe de proyectos 1985

  6. Applied Physics Education: PER focused on Physics-Intensive Careers

    Science.gov (United States)

    Zwickl, Benjamin

    2017-01-01

    Physics education research is moving beyond classroom learning to study the application of physics education within STEM jobs and PhD-level research. Workforce-related PER is vital to supporting physics departments as they educate students for a diverse range of careers. Results from an on-going study involving interviews with entry-level employees, academic researchers, and supervisors in STEM jobs describe the ways that mathematics, physics, and communication are needed for workplace success. Math and physics are often used for solving ill-structured problems that involve data analysis, computational modeling, or hands-on work. Communication and collaboration are utilized in leadership, sales, and as way to transfer information capital throughout the organization through documentation, emails, memos, and face-to-face discussions. While managers and advisors think a physics degree typically establishes technical competency, communication skills are vetted through interviews and developed on the job. Significant learning continues after graduation, showing the importance of cultivating self-directed learning habits and the critical role of employers as educators of specialized technical abilities through on-the-job training. Supported by NSF DGE-1432578.

  7. Primer reporte de alcaptonuria en el Perú

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    Daniel Guillén-Mendoza

    Full Text Available La alcaptonuria es un error innato del metabolismo causado por la deficiencia de la homogentisiato 1,2 dioxidasa (HGD, produciéndose un exceso de ácido homogentísico (HGA. Se presenta el caso de una mujer de 57 años quien, desde que nació, su orina se tornaba de color negro; desde hacía 9 años presentaba una pigmentación verdosa en los lechos ungueales que no mejoró con tratamientos antifúngicos y en los últimos 9 meses presentó artrosis de articulaciones grandes que fue empeorando, forzándola a usar una silla de ruedas por el intenso dolor generado por la artrosis de caderas y columna lumbar. Por la descripción de los síntomas se le solicitó la medición de HGA en orina lo que confirmó el diagnóstico de alcaptonuria. Se sugirieron analgésicos, dieta sin productos que contuvieran tirosina y fue referida para cirugía de reemplazo de cadera. Se trata del primer reporte de caso de alcaptonuria en el Perú.

  8. El sistema nacional de salud en el Perú

    Directory of Open Access Journals (Sweden)

    Francisco Sánchez-Moreno

    Full Text Available Un grupo de profesionales en el Perú, conocedores de sistemas nacionales de salud, conformado desde 1975, comenzó un proceso que llevó al país a ser el primero en América del Sur en iniciar la organización moderna de este sistema. El avance pionero que significó la creación del Sistema Nacional de Servicios de Salud en 1978 ocurrió antes de las reformas de los sistemas de salud en Chile (1980, Brasil (1990, Colombia (1993 y Ecuador (2008. El alentador inicio tuvo vaivenes reformistas permanentes desde entonces, con evolución negativa por falta de una política de Estado. Las características actuales del sistema peruano son el desempeño ineficiente y la discontinuidad, sin evaluación alguna, lo que determina un gran atraso con relación a los sistemas de salud de América. En el siglo XXI se han desaprovechado importantes esfuerzos técnicos para modernizar el sistema y sus funciones. El futuro es preocupante y el papel de las nuevas generaciones será decisivo.

  9. Microtubular Fuel Cell with Ultrahigh Power Output per Footprint.

    Science.gov (United States)

    Miao, Shiding; He, Shulian; Liang, Mengnan; Lin, Gungun; Cai, Bin; Schmidt, Oliver G

    2017-09-01

    A novel realization of microtubular direct methanol fuel cells (µDMFC) with ultrahigh power output is reported by using "rolled-up" nanotechnology. The microtube (Pt-RuO2 -RUMT) is prepared by rolling up Ru2 O layers coated with magnetron-sputtered Pt nanoparticles (cat-NPs). The µDMFC is fabricated by embedding the tube in a fluidic cell. The footprint of per tube is as small as 1.5 × 10-4 cm2 . A power density of ≈257 mW cm-2 is obtained, which is three orders of magnitude higher than the present microsized DFMCs. Atomic layer deposition technique is applied to alleviate the methanol crossover as well as improve stability of the tube, sustaining electrolyte flow for days. A laminar flow driven mechanism is proposed, and the kinetics of the fuel oxidation depends on a linear-diffusion-controlled process. The electrocatalytic performance on anode and cathode is studied by scanning both sides of the tube wall as an ex situ working electrode, respectively. This prototype µDFMC is extremely interesting for integration with micro- and nanoelectronics systems. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. An examination of periodontal treatment and per member per month (PMPM medical costs in an insured population

    Directory of Open Access Journals (Sweden)

    Papapanou Panos

    2006-08-01

    Full Text Available Abstract Background Chronic medical conditions have been associated with periodontal disease. This study examined if periodontal treatment can contribute to changes in overall risk and medical expenditures for three chronic conditions [Diabetes Mellitus (DM, Coronary Artery Disease (CAD, and Cerebrovascular Disease (CVD]. Methods 116,306 enrollees participating in a preferred provider organization (PPO insurance plan with continuous dental and medical coverage between January 1, 2001 and December 30, 2002, exhibiting one of three chronic conditions (DM, CAD, or CVD were examined. This study was a population-based retrospective cohort study. Aggregate costs for medical services were used as a proxy for overall disease burden. The cost for medical care was measured in Per Member Per Month (PMPM dollars by aggregating all medical expenditures by diagnoses that corresponded to the International Classification of Diseases, 9th Edition, (ICD-9 codebook. To control for differences in the overall disease burden of each group, a previously calculated retrospective risk score utilizing Symmetry Health Data Systems, Inc. Episode Risk Groups™ (ERGs were utilized for DM, CAD or CVD diagnosis groups within distinct dental services groups including; periodontal treatment (periodontitis or gingivitis, dental maintenance services (DMS, other dental services, or to a no dental services group. The differences between group means were tested for statistical significance using log-transformed values of the individual total paid amounts. Results The DM, CAD and CVD condition groups who received periodontitis treatment incurred significantly higher PMPM medical costs than enrollees who received gingivitis treatment, DMS, other dental services, or no dental services (p Conclusion This two-year retrospective examination of a large insurance company database revealed a possible association between periodontal treatment and PMPM medical costs. The findings suggest that

  11. Linee guida per la gestione della Volpe in Italia

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    Silvano Toso

    2003-10-01

    Full Text Available La plasticità ecologica della Volpe (Vulpes vulpes fa di questa specie il Carnivoro più diffuso e più adattabile al mondo. Proprio per la sua diffusione la Volpe è oggetto di un intenso prelievo sia venatorio, sia finalizzato a contenerne l'impatto predatorio ed allo sfruttamento commerciale della pelliccia. In Italia esiste una forte pressione dei cacciatori perché si realizzino programmi di controllo delle popolazioni di questo predatore, al fine di ridurne l'impatto sulle specie d'interesse cinegetico. Gli effetti del contenimento della Volpe sulla dinamica delle popolazioni di specie preda sono stati oggetto di numerosi studi, ma i risultati di tali ricerche non sono univoci; se in alcuni casi si è infatti verificato, in seguito a decrementi delle popolazioni di Volpe, un incremento di consistenza e successo riproduttivo delle specie preda, in altri casi non si è registrato alcun significativo effetto demografico. Ancora meno chiaro è quale sia la soglia di contrazione delle popolazioni di Volpe necessaria per ottenere un effetto significativo sulle popolazioni delle specie preda, considerato che questo Carnivoro ha un potenziale riproduttivo elevato ed un'organizzazione sociale che determina la rapida rioccupazione dei territori lasciati liberi. La legislazione italiana in materia di controllo è, rispetto ad altri paesi europei ed extraeuropei, particolarmente rigida: la legge n. 157/92 identifica infatti un obiettivo generale di mantenimento delle popolazioni dei predatori a livelli adeguati ad assicurare una funzione regolatrice delle biocenosi. La stessa norma impone inoltre che ogni intervento di abbattimento di predatori finalizzato al contenimento dei danni da essi arrecati sia autorizzato dalla Regione o dalla Provincia competente, sulla base di un parere tecnico dell'INFS che è chiamato a verificare l'inapplicabilità di metodi incruenti di prevenzione dei danni, la selettività delle tecniche di abbattimento e la

  12. Final Report of the HyPER Harvester Project

    Energy Technology Data Exchange (ETDEWEB)

    Prasad, Nadipuram R [New Mexico State Univ., Las Cruces, NM (United States); Ranade, Satishkuma J [New Mexico State Univ., Las Cruces, NM (United States)

    2015-11-30

    The HyPER Harvester Project resulted in the first full­scale design, fabrication and testing of two vertical­axis harvester prototypes at the Elephant Butte Irrigation District Drop 8 Station in Southern New Mexico. The design, followed by fabrication, and deployment clearly demonstrated the feasibility to manufacture and deploy harvester prototypes at low cost. While several issues common to irrigation canal systems have to be overcome, the electromechanical performance of the integrated turbine­generator system demonstrated proof­of­concept. Proof­of­concept includes 1) feasibility for using additive manufacturing techniques to fabricate Carbon­composite turbine­generator components at low cost, 2) ease of transportation and deployment, and 3) the harvester performance. The benefits of modularity were demonstrated in terms of rapid deployment at the Drop 8 Station. Scalability and adaptability were proven in terms of the custom­fitting characteristics that enabled rapid deployment. While keeping the same shape and form, the harvester can be easily adapted to any drop environment. Self­supporting ability makes the harvester design minimally intrusive on existing structures. There are two technical challenges ahead that have to be addressed. Irregular flow patterns in canal flow induce vertical oscillations due to pressure change across the impeller. Despite the nosecone in conventional Kaplan turbine design that ordinarily dampens oscillations, an effective coupling design is required to eliminate the hydrodynamic effect on the generating system. In arid areas where tumbleweed is present, a robust design to prevent trash entering the drop is required. The compact shape and form have an aesthetic appearance and appear to illustrate an environmentally friendly attribute. The systems­engineered design enables rapid manufacturing and assembly of desired size units that can be deployed at sites along U.S. waterways as small hydropower plants. There is

  13. Modelling Per Capita Water Demand Change to Support System Planning

    Science.gov (United States)

    Garcia, M. E.; Islam, S.

    2016-12-01

    Water utilities have a number of levers to influence customer water usage. These include levers to proactively slow demand growth over time such as building and landscape codes as well as levers to decrease demands quickly in response to water stress including price increases, education campaigns, water restrictions, and incentive programs. Even actions aimed at short term reductions can result in long term water usage declines when substantial changes are made in water efficiency, as in incentives for fixture replacement or turf removal, or usage patterns such as permanent lawn watering restrictions. Demand change is therefore linked to hydrological conditions and to the effects of past management decisions - both typically included in water supply planning models. Yet, demand is typically incorporated exogenously using scenarios or endogenously using only price, though utilities also use rules and incentives issued in response to water stress and codes specifying standards for new construction to influence water usage. Explicitly including these policy levers in planning models enables concurrent testing of infrastructure and policy strategies and illuminates interactions between the two. The City of Las Vegas is used as a case study to develop and demonstrate this modeling approach. First, a statistical analysis of system data was employed to rule out alternate hypotheses of per capita demand decrease such as changes in population density and economic structure. Next, four demand sub-models were developed including one baseline model in which demand is a function of only price. The sub-models were then calibrated and tested using monthly data from 1997 to 2012. Finally, the best performing sub-model was integrated with a full supply and demand model. The results highlight the importance of both modeling water demand dynamics endogenously and taking a broader view of the variables influencing demand change.

  14. PER LA DIDATTICA DI UNA SCRITTURA ESPOSITIVA: LA RELAZIONE

    Directory of Open Access Journals (Sweden)

    Massimo Prada

    2014-07-01

    Full Text Available In questo articolo si descrive – con una specifica attenzione alle ricadute didattiche – la relazione in quanto tipo testuale, discorsivo e linguistico e si forniscono indicazioni operative utili alla stesura di relazioni corrette, adeguate ed efficaci. Il testo delinea così un possibile percorso formativo per migliorare – in un ambito ben determinato dello “scrivibile” – le competenze scrittura degli studenti della scuola secondaria di secondo grado. La prima parte del documento sottolinea le caratteristiche generali della relazione in quanto classe di testi e individua i tratti distintivi di sue forme particolarmente utili e praticabili in ambito scolastico: il verbale, il rapporto e la relazione di ricerca, il saggio breve e la recensione. La seconda parte, invece, si focalizza sul processo cognitivo e operativo che rende possibile la scrittura di relazioni funzionali, individuando un possibile itinerario compositivo distinto in fasi: quella della lettura dei testi fonte e della loro manipolazione; quella della vera e propria stesura progettuale; quella della revisione. Teaching expository writing: a report  Massimo Prada  With a specific focus on educational implications, this article describes the report as a textual, discursive and linguistic type and provides useful guidance useful for writing correct, appropriate and effective reports. In the well-defined area of “writablility”, the text outlines a possible way to improve teaching writing skills to secondary school students. The first part of the paper outlines the general characteristics of the report as a class of text and identifies the distinctive features of its form that are particularly useful and practicable in schools: memorandums, reports and research reports, short essays and reviews. The second part focuses on the cognitive and operational processes that makes it possible to write functional reports, identifying a possible distinct compositional stages

  15. Mappe interattive per la promozione turistico-culturale

    Directory of Open Access Journals (Sweden)

    Antonella Lerario

    2014-04-01

    Full Text Available IT L’ingente patrimonio culturale italiano affronta oggi le conseguenze di strategie di promozione obsolete e di un insufficiente uso delle ICT, ma soprattutto di una errata percezione del suo significato nella vita delle comunità. I caratteri stessi del c.d. ‘Museo Italia’(un patrimonio di beni ‘minori’ fortemente diffuso sul territorio accanto ai più noti beni monumentali richiedono notevoli cambiamenti nei progetti di promozione sia nel senso di un trasferimento alla scala locale dei processi, sia nella identificazione e modellazione dell’utenza potenziale. Sul piano operativo ciò implica il ricorso a strumenti tecnologici semplici e fortemente interattivi, incentrati sui bisogni di informazione dell’utente medio, potenziale visitatore. L’articolo illustra il sistema sviluppato da ITC-CNR (Bari nell’ambito del progetto 'Smart Cities’ per la città di Siracusa, basato su procedure e software che semplificano la pubblicazione di informazione georeferenziata.ENThe huge cultural heritage of Italy is facing the consequences of obsolete promotion strategies and of an under exploitation of ICTs, but above all of a wrong perception of its significance in communities’ life. The inherent characters of the so-called ‘Museum Italy’ (a wealth of ‘minor’ assets, diffused on the territory, together with the more famous monuments demand substantial modifications in promotion projects, in terms of both a downscaling of processes and of identification and modelling of potential users’ behaviour. On the operational level, this requires the elaboration of simple and highly interactive technological tools, focused on the ‘average’ user’s  information needs, or potential visitor. The article presents the system developed by ITC-CNR (Bari within the ‘Smart Cities’ project for the city of Siracusa (Sicily, based on software and procedures aimed at simplifying the publication of georeferenced information.

  16. Per una nuova traduzione di Winnie Ille Pu: da libro per l’infanzia a “classico latino”

    Directory of Open Access Journals (Sweden)

    Elena Scuotto

    2016-06-01

    Full Text Available Il seguente contributo prende in considerazione la traduzione latina del classico della letteratura per l’infanzia Winnie-the-Pooh di A.A. Milne, fatta dall’ungherese Lénárd Sándor come Winnie Ille Pu. L’attenzione si soffermerà nello specifico sulla nuova edizione francese del romanzo a cura di Florient Azoulay che traduce dal latino e non dall’inglese, considerando quindi la versione di Lénárd come un classico autonomo. The following contribution aims at analysing the Latin translation of the children literature classic Winnie-the-Pooh by A.A. Milne, made by Hungarian Lénárd Sándor as Winnie Ille Pu. In particular, I will focus my attention on the new French edition of the novel edited by Florient Azouly, who has translated it from Latin and not from English, considering Lénárd’s version as an autonomous classic itself.

  17. Energy analysis in Cynodon dactylon (L.) Pers hay production; Analise energetica na producao de feno de Cynodon dactylon (L.) Pers

    Energy Technology Data Exchange (ETDEWEB)

    Campos, Alessandro T. [UNIOESTE, Marechal Candido Rondon, PR (Brazil). Centro de Ciencias Agrarias]. E-mail: atcampos3@yahoo.com.br; Saglietti, Jose R.C.; Bueno, Osmar C. [UNESP, Botucatu, SP (Brazil). Facudade de Ciencias Agronomicas; Campos, Aloisio T. [EMBRAPA - Gado de leite, Juiz de Fora, MG (Brazil)

    2005-05-15

    The aim of this work was to characterize the energy consumption related to the introduction, development, hay processing and storage of Cynodon dactylon (L.) Pers allied to the analysis of the energetic efficiency. The data used in this project were collected from EMBRAPA Gado de Leite, localized in Coronel Pacheco, Minas Gerais, Brazil. The data were obtained from a seven year period of an intensive system of milk production. Energetic coefficients were used to generate the survey and several matrix components obtained from pertinent literature. The direct energy, related to the inputs, showed more efficient participation on the energetic matrix than the indirect energy and the percentages were 94.64 and 5.31, respectively. Farm tractor was the main indirect energy consumer, which is responsible for turning on all the equipment, followed by the irrigation system. The energetic efficiency presented by the whole system was 4.2, being considered positive and demonstrating that the agriculture ecosystem is sustainable. Most of the direct energy employed in this system was oil derived on fuel form. There was, however, a great consume of another oil derived energy such as fertilizer, but mainly on the nitrogen form (28.89% of the total employed energy). (author)

  18. Buone pratiche didattiche per prevenire falsi positivi nelle diagnosi di discalculia: il progetto “PerContare”

    Directory of Open Access Journals (Sweden)

    Anna Ethelwyn Baccaglini-Frank

    2015-12-01

    Full Text Available Per contrastare il fenomeno dei falsi positivi nelle diagnosi di discalculia in Italia, tra i bambini di terza elementare, è stato realizzato un progetto triennale (2011-2014, fondato sulla collaborazione tra ricercatori in psicologia e didattica della matematica. Durante il progetto sono state elaborate e sperimentate pratiche didattiche atte a prevenire e affrontare difficoltà di apprendimento nell’ambito dell’aritmetica all’inizio della scuola primaria. In questo articolo vengono discusse le basi su cui si fonda il progetto, in particolare le basi scientifiche dei materiali didattici elaborati, di cui verranno proposti alcuni esempi. Tali esempi sono prototipici rispetto all’attenzione verso un approccio cinestetico-tattile e visuo-spaziale alla matematica. Le pratiche didattiche proposte hanno portato gli studenti ad interiorizzare relazioni parte-tutto e a pensare alla moltiplicazione in maniera strutturale, attraverso appositi diagrammi. Saranno forniti dati quantitativi e discussi brevemente dati qualitativi che confermano l’efficacia delle pratiche didattiche proposte.

  19. Scaling vectors of attoJoule per bit modulators

    Science.gov (United States)

    Sorger, Volker J.; Amin, Rubab; Khurgin, Jacob B.; Ma, Zhizhen; Dalir, Hamed; Khan, Sikandar

    2018-01-01

    Electro-optic modulation performs the conversion between the electrical and optical domain with applications in data communication for optical interconnects, but also for novel optical computing algorithms such as providing nonlinearity at the output stage of optical perceptrons in neuromorphic analog optical computing. While resembling an optical transistor, the weak light–matter-interaction makes modulators 105 times larger compared to their electronic counterparts. Since the clock frequency for photonics on-chip has a power-overhead sweet-spot around tens of GHz, ultrafast modulation may only be required in long-distance communication, not for short on-chip links. Hence, the search is open for power-efficient on-chip modulators beyond the solutions offered by foundries to date. Here, we show scaling vectors towards atto-Joule per bit efficient modulators on-chip as well as some experimental demonstrations of novel plasmonic modulators with sub-fJ/bit efficiencies. Our parametric study of placing different actively modulated materials into plasmonic versus photonic optical modes shows that 2D materials overcompensate their miniscule modal overlap by their unity-high index change. Furthermore, we reveal that the metal used in plasmonic-based modulators not only serves as an electrical contact, but also enables low electrical series resistances leading to near-ideal capacitors. We then discuss the first experimental demonstration of a photon-plasmon-hybrid graphene-based electro-absorption modulator on silicon. The device shows a sub-1 V steep switching enabled by near-ideal electrostatics delivering a high 0.05 dB V‑1 μm‑1 performance requiring only 110 aJ/bit. Improving on this demonstration, we discuss a plasmonic slot-based graphene modulator design, where the polarization of the plasmonic mode aligns with graphene’s in-plane dimension; where a push–pull dual-gating scheme enables 2 dB V‑1 μm‑1 efficient modulation allowing the device to be just

  20. Proposta per una classificazione dei dati sperimentali in sismologia

    Directory of Open Access Journals (Sweden)

    G. PANNOCCHIA

    1974-06-01

    Full Text Available T Centri Internazionali clic elaborano i d a t i di t u t ti gli Osservatori sismologici allo scopo di determinare i p a r a m e t r i fondamentali dogli eventi sismici, forniscono generalmente questi p a r a m e t r i con i corrispondenti errori calcolati. Nel presente lavoro, dopo alcuni rilievi di c a r a t t e r e generale, è s t a ta messa in evidenza l ' o p p o r t u n i t à di dare un aspetto significativo alle conseguenze che hanno gli inevitabili errori dovuti al rilevamento sperimentale dei dati di osservazione. In particolare è s t a t a r i c h i a m a t a l'attenzione: I sul f a t t o elio l ' i n t e r p r e t a z i o n e d i r e t t a di un sismogramma non fornisce una distanza A sufficientemente precisa; I I sull'importanza che hanno gli errori + STI corrispondenti ai tempi origine e le conseguenze che ne derivano, specialmente per valori elevali di | SH |; I I I sul significato e l ' i m p o r t a n z a che hanno gli errori corrispondenti alle coordinate epicentrali ed alla p r o f o n d i t à ipocentrale; IV sul significato e l ' i m p o r t a n z a clic hanno i residui ( 0 — ( ' = (tempi osservati — tempi calcolati relativi ai iP di ciascuna stazione (lP = tempi di t r a g i t t o delle onde longitudinali. Tenendo presenti questi punti viene proposta una classificazione di c a r a t t e r e analitico e di uso pratico (Fig. 2 in 4 classi

  1. Births per U.S. woman? Depends on race, ethnicity.

    Science.gov (United States)

    Haub, C

    1993-09-01

    A profile of mothers giving birth is presented for the US for 1990 based on race and ethnicity. Some of the complexities involved in compiling racial and ethnic data are described. The total fertility rate was 2.1 for all American women, 1.1 for Japanese Americans, and 3.2 for Hawaiians and Mexican Americans. The number of births per woman was derived from state birth registration data, which culls data from preadmission hospital forms filled out by the mother. The denominator of the birth rate comes from the number of women in the specified age group as determined by the Census. The problem arises from self-reports themselves. Consistency between recording systems has been improved since 1989 when births were counted based on mother's race and ethnicity. There have been greater percentages of interracial births for which race of both parents were known, and the trend was for 15% of the births for race of the father not to be reported in 1990. The data revealed that in 1990, Mexican Americans and Hawaiians had the highest birth rate of 3.2, which was comparable to developing countries in Latin America. The other Hispanic group was another high fertility group for a developed country. Low fertility was found among Japanese, Chinese, and Cuban Americans. The actual numbers revealed that non-Hispanic whites constitute 2.6 million out of 4.2 million children born in the US. 595,100 were Hispanics, 661,700 were non-Hispanic blacks, 142,000 were Asian or Pacific Islander, and less than 40,000 were American Indian. Teenage pregnancy was considerable among the ethnic populations: nearly 25% of African Americans, and about 20% of American Indians, Puerto Ricans, Hawaiians, and Mexican Americans having births to women under 20 years of age. The birthing patterns were different among minority groups. Hispanic women had early childbearing and continued childbearing throughout the reproductive years. Black and American Indian women tended to complete childbearing early. Asian

  2. Per una educazione linguistica trasversale: la sfida della competenza multilingue.

    Directory of Open Access Journals (Sweden)

    Luciano Mariani

    2009-12-01

    Full Text Available Normal 0 14 MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabella normale"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman";} Insegnare e apprendere più lingue in un curricolo consente di sviluppare una competenza comunicativa plurilingue e pluriculturale: una multicompetenza che, sulla base dell’interdipendenza tra apprendimenti linguistici (L1, L2, Ln …, implica un trasferimento di conoscenze, abilità e convinzioni/atteggiamenti tra le lingue. L’integrazione tra apprendimenti presuppone però un’integrazione tra insegnamenti, ossia una cultura della scuola e della classe basata sulla collaborazione – una condivisione e negoziazione di teorie, metodologie e prassi che rinnovi la sfida di un’educazione linguistica trasversale.  Normal 0 14 MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabella normale"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman";} Learning and teaching several languages in a curriculum allows the development of a plurilingual and pluricultural communicative competence: a multicompetence based on the interdependence of language learning (L1, L2, Ln …, which implies a transfer of knowledge, abilities and beliefs/attitudes between languages. Integrating different language learning experiences, however, involves integrating teaching experiences, i.e. a school and class culture based on collaboration – sharing and negotiating theories, methodologies and practices as a way to reaffirm a cross

  3. Proposta per la implantació d'un sistema de gestió de manteniment asistit per ordinador (GMAO) a una empresa farmacèutica

    OpenAIRE

    Visa Catalàn, Sergi

    2013-01-01

    Es presenta el projecte per implantar un software de Gestió de Manteniment Assistit per Ordinador (GMAO) en un edifici d’oficines d’una empresa farmacèutica. A l’edifici es fan tres tipus de manteniment: correctiu, conductiu i preventiu. Com a requeriment inicial, el GMAO, ha de donar entrada a equips electrònics com a terminals per reduir feina de transmissió de dades, per eliminar el paper com a canal de comunicació i per eliminar els arxius físics un cop implantat del GMAO. Estudis que ...

  4. El testimonio inca de la conquista del Perú

    Directory of Open Access Journals (Sweden)

    1978-01-01

    Full Text Available Ce témoignage de Cayo Inga est un document important qui retrace les succès des premières années de la pénétration espagnole au Pérou, de la côte de Tumbes à la ville de Cuzco. Sa valeur exceptionnelle tient à la qualité de l'informateur-membre du lignage inca et au fait qu'il ait été un témoin personnel des faits qu'il décrit. Par ce manuscrit, nous savons que Waskar Inga connut opportunément l'invasion étrangère à partir de la côte de Tumbes et que les Espagnols exigèrent une rançon au captif Atao Wallpa lui promettant de relâcher après. Nous sommes également renseignés sur le fameux pillage du temple de Pachacamac, sur la dramatique demande d'Atao Wallpa suppliant d'être exilé en Espagne et sur l'emprisonnement de Mango Inga Yupangui. Enfin, ce manuscrit éclaircit quelques faits quant aux sièges de la ville de Cuzco et de celle de Lima en 1536. El testimonio de Cayo Inga, es un documento excepcional para rehacer los sucesos de los primeros años de la penetración española en el Perú, de la costa tumbesina a la ciudad del Cuzco primero por la calidad del informante miembro del linaje Inca y segundo por su presencialidad en el lugar de los hechos. Este manuscrito, aclara que Waskar Inga conoció oportunamente la invasión de la costa tumbesina por los extranjeros y refiere que los españoles exigieron al cautivo Atao Wallpa un rescate, prometiéndole soltarlo después. Reseña a la vez el famoso saqueo del adoratorio de Pachacamac, el dramático pedido de Atao Wallpa para que lo exiliaran a España y el prendimiento de Mango Inga Yupangui, finalmente aporta datos sobre los asedios de la ciudad del Cuzco y de Lima en 1536. Cayo Inga's testimony is a document of exceptional value in the retracing of the events of the first years of the Spanish invasion and occupation of the country from Tumbes to Cuzco. It is remarkable for the quality of the source of information, since the reporter was both a member of the Inca

  5. rPer1 and rPer2 induction during phases of the circadian cycle critical for light resetting of the circadian clock.

    Science.gov (United States)

    Nagano, Mamoru; Adachi, Akihito; Masumoto, Koh-hei; Meyer-Bernstein, Elizabeth; Shigeyoshi, Yasufumi

    2009-09-15

    Photic resetting of a biological clock is one of the fundamental characteristics of circadian systems and allows living organisms to adjust to a particular environment. Nocturnal light induces the Per1 and Per2 genes, which leads to a resetting of the circadian clock in the suprachiasmatic nucleus (SCN), the mammalian circadian center. In our present study, we investigated whether light differentially induces the rat Per1 (rPer1) and Per2 (rPer2) genes to enable resetting of their circadian clocks. In a 24-hour LD cycle (12 h light:12 h dark), which is shorter than the normal free-running period for rats, Per1 alone showed strong induction in the ventrolateral region of the SCN (VLSCN) during the early day. In contrast, in a 25 hour LD cycle (12.5 h light:12.5 h dark), which is longer than the free running period for these animals, rPer2 alone was strongly induced in the VLSCN, at the end of the light phase and during the early dark periods. Our current findings therefore suggest that Per1 and Per2 are differentially regulated for daily entrainment to the LD cycle.

  6. Nuove prospettive per la storia d'impresa

    Directory of Open Access Journals (Sweden)

    Amedeo Lepore

    2010-12-01

    Full Text Available La historia de la empresa es una disciplina abierta que puede incluir, además de las cuestiones relacionadas con la evolución de la economía, las empresas, el mercado y el mundo empresarial, otros ámbitos institucionales, culturales y sociales relacionados con los acontecimientos contemporáneos como resultado de un largo proceso de industrialización. La primera revolución industrial se inició a finales del siglo XVIII, seguida por una profunda transformación industrial que tuvo lugar en la segunda mitad del siglo XIX, la industrialización masiva del siglo XX y el nuevo escenario post-fordista del siglo XXI son los hitos históricos de un fenómeno que ha acompañado las diferentes etapas de desarrollo y la economía mundial durante el período que se caracterizó por la supremacía de la producción capitalista. En resumen, la historia de la empresa es un elemento esencial, en términos de calidad, para la comprensión de la estructura económica de un país desde una perspectiva dinámica y un punto de vista comparativo. No es sorprendente que, a comienzos del siglo XX la historia de la empresa saltó de los Estados Unidos en relación con el modelo del "big business", como un análisis y un profundo examen de la actividad, incluso de un aspecto crítico, se dirigió a algunos tipos de desarrollo y estrategias de la empresa. Como está escrito por Alfred D. Chandler: «La historia de la empresa apareció por primera vez como distinguible sub-campo de la historia económica a finales de los 1920 y en los 1930. Su predecesor, la historia económica, se convirtió en una disciplina identificable sólo unos años antes». La primera Cátedra de Historia de la Empresa se activó en 1927 en la Harvard Business School, y fue cubierta hasta mediados del siglo pasado por Norman SB Gras, que se ha decidido dividir la historia de la empresa en seis periodos diferentes: “Pre-business capitalism”, “Petty capitalism”,

  7. Una strategia semplice per la GPS Seismology e i sistemi di early warning per gli tsunami denominata VADASE

    Directory of Open Access Journals (Sweden)

    Mattia Crespi

    2011-04-01

    Full Text Available I recenti avvenimenti legati al fortissimo terremoto avvenuto in Giappone lo scorso 11 marzo 2011 e al tragico e devastante tsunami ad esso conseguente hanno, una volta di più, posto all'attenzione della comunità internazionale la necessità di disporre sistemi di early warning per gli tsunami sempre più efficienti. I sistemi GNSS, se utilizzati in modo adeguato, possono dare un grande contributo come nel caso della tecnica VADASE qui esposta. Co-seismic Displacement Estimation. Improving Tsunami Early Warning Systems The great earthquake (M=9.0 which hit the Island of Honshu (Japan on March 11, 2011 and generated a tremendous tsunami raised once more the attention towards tsunami early warning systems.In this respect, during the last years, several studies demonstrated that GPS can be used effectively for estimating coseismic displacement waveforms (so called GPS seismol-ogy, with accuracies ranging from a few millimeters to a few centimeters. These stud-ies were mainly developed off-line, re-analysing the GPS data acquired during strong earthquakes and well known processing strategies (Precise Point Positioning and In-dependent Positioning were developed to lower the latency between the earthquake occurrence and the coseismic displacement waveforms estimation as much as possible. In this regard, during the Real Time GPS Science Requirements Workshop held in Sep-tember 2007 in Leavenworth (Washington, USA the goal of achieving 1 cm real-time GNSS displacement accuracies in the global reference frame within 3 minutes following an earthquake was adopted.It is in this frame that here we present a novel approach named VADASE, with which we are able to estimate accurate co-seismic displacement waveforms in real-time, just using the standard broadcast products (orbits and clocks and the high-rate (1Hz or more carrier phase observations continuously collected by a GPS receiver. Since no other data than those routinely collected by a

  8. Tipificación Molecular del Vibrio cholerae O1 en el Perú

    Directory of Open Access Journals (Sweden)

    Huguet T José

    2000-01-01

    Full Text Available Este estudio de ribotipificación en 75 cepas de Vibrio cholerae O1 permitió identificar tres variantes ribotípicas, referidas como Per1, Per2 y Per3, aisladas durante el periodo 1991- 1999 en el Perú. La variante Per1 fue reportada tanto en la etapa epidémica y endémica del cólera, mientras que Per2 y Per3 se relacionaron sólo con la etapa endémica. Los resultados mostraron además una aparición constante y mayoritaria de la variante Per1, poniendo en evidencia la emergencia de un mismo grupo clonal en los brotes epidémicos del Perú. Las variantes ribotípicas encontradas fueron comparadas con los ribotipos de diferentes cepas referenciales de V. cholerae previamente caracterizadas. Se observó una identidad total del ribotipo Per1 con la variante ribotípica de aislamientos Asiáticos (Tailandia, encontrándose además altos índices de similitud entre los ribotipos Per1, Per2 y Per3, y evidenciándose una estrecha relación entre las cepas peruanas y los aislamientos asiáticos.

  9. Multiple 60-Minute Massages per Week Offer Relief for Chronic Neck Pain

    Science.gov (United States)

    ... Minute Massages per Week Offer Relief for Chronic Neck Pain Share: © Bob Stockfield Courtesy: National Center for Complementary ... fewer or shorter sessions for people with chronic neck pain, suggesting that several hour-long massages per week ...

  10. 47 CFR 64.1509 - Disclosure and dissemination of pay-per-call information.

    Science.gov (United States)

    2010-10-01

    ... CARRIER SERVICES (CONTINUED) MISCELLANEOUS RULES RELATING TO COMMON CARRIERS Interstate Pay-Per-Call and... pursuant to § 64.1512 for failure to pay legitimate pay-per-call charges. Disclosure statements must be...

  11. 47 CFR 64.1512 - Involuntary blocking of pay-per-call services.

    Science.gov (United States)

    2010-10-01

    ... CARRIER SERVICES (CONTINUED) MISCELLANEOUS RULES RELATING TO COMMON CARRIERS Interstate Pay-Per-Call and... paid, legitimate pay-per-call charges, except that a subscriber who has filed a complaint regarding a...

  12. Wealth of the world's richest publicly traded companies per industry and per employee: Gamma, Log-normal and Pareto power-law as universal distributions?

    Science.gov (United States)

    Soriano-Hernández, P.; del Castillo-Mussot, M.; Campirán-Chávez, I.; Montemayor-Aldrete, J. A.

    2017-04-01

    Forbes Magazine published its list of leading or strongest publicly-traded two thousand companies in the world (G-2000) based on four independent metrics: sales or revenues, profits, assets and market value. Every one of these wealth metrics yields particular information on the corporate size or wealth size of each firm. The G-2000 cumulative probability wealth distribution per employee (per capita) for all four metrics exhibits a two-class structure: quasi-exponential in the lower part, and a Pareto power-law in the higher part. These two-class structure per capita distributions are qualitatively similar to income and wealth distributions in many countries of the world, but the fraction of firms per employee within the high-class Pareto is about 49% in sales per employee, and 33% after averaging on the four metrics, whereas in countries the fraction of rich agents in the Pareto zone is less than 10%. The quasi-exponential zone can be adjusted by Gamma or Log-normal distributions. On the other hand, Forbes classifies the G-2000 firms in 82 different industries or economic activities. Within each industry, the wealth distribution per employee also follows a two-class structure, but when the aggregate wealth of firms in each industry for the four metrics is divided by the total number of employees in that industry, then the 82 points of the aggregate wealth distribution by industry per employee can be well adjusted by quasi-exponential curves for the four metrics.

  13. 78 FR 28949 - Fund Availability Under VA's Homeless Providers Grant and Per Diem Program (Rehabilitation)

    Science.gov (United States)

    2013-05-16

    ... Homeless Providers Grant and Per Diem Program, Department of Veterans Affairs, 10770 North 46th Street... AFFAIRS Fund Availability Under VA's Homeless Providers Grant and Per Diem Program (Rehabilitation) AGENCY... grantee facilities originally funded under VA's Homeless Providers Grant and Per Diem Program (see funding...

  14. 77 FR 39342 - Proposed Information Collection (Homeless Providers Grant and Per Diem Program) Activity; Comment...

    Science.gov (United States)

    2012-07-02

    .../or per diem for programs to assist homeless veterans' transition to independent living and to... AFFAIRS Proposed Information Collection (Homeless Providers Grant and Per Diem Program) Activity; Comment.... Titles a. Homeless Providers Grant and Per Diem Program, Capital Grant. Application, VA Form 10-0361-CG...

  15. 42 CFR 413.77 - Direct GME payments: Determination of per resident amounts.

    Science.gov (United States)

    2010-10-01

    ... hospital that either had direct GME costs or received indirect education payment in its cost reporting... nonprimary care per resident amounts. A hospital's per resident amount is an amount inclusive of any CPI-U... before October 1, 2002, the updated weighted mean value of per resident amounts of all hospitals located...

  16. 7 CFR 1205.514 - Customs Service and the Collection of the $1 per bale assessment.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Customs Service and the Collection of the $1 per bale assessment. 1205.514 Section 1205.514 Agriculture Regulations of the Department of Agriculture (Continued... Service and the Collection of the $1 per bale assessment. The Collection of the $1 per bale assessment by...

  17. 76 FR 63936 - Notice of Adjustment of Countywide Per Capita Impact Indicator

    Science.gov (United States)

    2011-10-14

    ... SECURITY Federal Emergency Management Agency Notice of Adjustment of Countywide Per Capita Impact Indicator... countywide per capita impact indicator under the Public Assistance program for disasters declared on or after...-wide per capita indicator to evaluate the impact of the disaster at the county level. FEMA will adjust...

  18. 78 FR 64232 - Notice of Adjustment of Statewide Per Capita Impact Indicator

    Science.gov (United States)

    2013-10-28

    ... SECURITY Federal Emergency Management Agency Notice of Adjustment of Statewide Per Capita Impact Indicator... statewide per capita impact indicator under the Public Assistance program for disasters declared on or after... INFORMATION: 44 CFR 206.48 provides that FEMA will adjust the statewide per capita impact indicator under the...

  19. 75 FR 62135 - Notice of Adjustment of Countywide Per Capita Impact Indicator

    Science.gov (United States)

    2010-10-07

    ... SECURITY Federal Emergency Management Agency Notice of Adjustment of Countywide Per Capita Impact Indicator... countywide per capita impact indicator under the Public Assistance program for disasters declared on or after... the countywide per capita impact indicator under the Public Assistance program to reflect annual...

  20. Melatonin Signal Transduction Pathways Require E-Box-Mediated Transcription of Per1 and Per2 to Reset the SCN Clock at Dusk.

    Directory of Open Access Journals (Sweden)

    Patty C Kandalepas

    Full Text Available Melatonin is released from the pineal gland into the circulatory system at night in the absence of light, acting as "hormone of darkness" to the brain and body. Melatonin also can regulate circadian phasing of the suprachiasmatic nucleus (SCN. During the day-to-night transition, melatonin exposure advances intrinsic SCN neural activity rhythms via the melatonin type-2 (MT2 receptor and downstream activation of protein kinase C (PKC. The effects of melatonin on SCN phasing have not been linked to daily changes in the expression of core genes that constitute the molecular framework of the circadian clock. Using real-time RT-PCR, we found that melatonin induces an increase in the expression of two clock genes, Period 1 (Per1 and Period 2 (Per2. This effect occurs at CT 10, when melatonin advances SCN phase, but not at CT 6, when it does not. Using anti-sense oligodeoxynucleotides (α ODNs to Per 1 and Per 2, as well as to E-box enhancer sequences in the promoters of these genes, we show that their specific induction is necessary for the phase-altering effects of melatonin on SCN neural activity rhythms in the rat. These effects of melatonin on Per1 and Per2 were mediated by PKC. This is unlike day-active non-photic signals that reset the SCN clock by non-PCK signal transduction mechanisms and by decreasing Per1 expression. Rather, this finding extends roles for Per1 and Per2, which are critical to photic phase-resetting, to a nonphotic zeitgeber, melatonin, and suggest that the regulation of these clock gene transcripts is required for clock resetting by diverse regulatory cues.

  1. per trip

    International Development Research Centre (IDRC) Digital Library (Canada)

    15 oct. 2017 ... CAYMAN ISLANDS / ÎLES CAÏMANS. Everywhere / Dans tout le ... COMORO ISLANDS / ÎLES COMORES. Everywhere / Dans tout le ... MADAGASCAR. Everywhere / Dans tout le pays. 246. MALAWI. Everywhere / Dans tout le pays. 205. MALAYSIA / MALAISIE. Everywhere / Dans tout le pays. 242. MALI.

  2. Nuove tecnologie per la green economy: utilizzo di drone in agricoltura e studi per l'utilizzo di Nicotiana tabacum L. come coltura oleaginosa

    OpenAIRE

    di Lucia, Francesco

    2016-01-01

    Uso del drone in agricoltura L'obiettivo di questo studio è stato quello di determinare la capacità di un veicolo aereo senza equipaggio (UAV) per acquisire immagini multitemporali in un campo di grano duro per la valutazione della variabilità di crescita delle colture in diverse fasi fenologiche. Sono stati effettuati 4 voli con telecamere RGB e NIR per stimare il Normalized Difference Vegetation Index (NDVI) e il suo rapporto con la biomassa e la copertura vegetale (LAI). Correlazioni s...

  3. Evaluation of the cost per patient per injection of botulinum toxin A in upper limb spasticity: comparison of two preparations in 19 countries

    Directory of Open Access Journals (Sweden)

    Valentine W

    2012-11-01

    Full Text Available Stéphane Roze,1 Hannah Kurth,2 Barnaby Hunt,3 William Valentine,3 Rémi Marty11HEVA, Lyon, France; 2Ipsen Pharma, Boulogne-Billancourt, France; 3Ossian Health Economics and Communications, Basel, SwitzerlandBackground: Botulinum toxin A injections are indicated for the management of movement disorders, including upper limb spasticity. The aim of this study was to compare the cost per patient per injection for two botulinum toxin A preparations in 19 countries.Methods: Doses of botulinum toxin A are expressed in noninterchangeable units (U, ie, Botox® in 100 Allergan units (100 U and Dysport® in 500 Speywood units (500 U. Recommended dosages were derived from country-specific summaries of product characteristics or prescribing information. Cost analysis was based on official list prices and expressed in 2011 Euros. The cost per patient per injection was calculated using the recommended dosage in upper limb spasticity combined with price per vial in each country.Results: For upper limb spasticity, the recommended dosage for Dysport in the summary of product characteristics is 1000 U per patient, whereas for Botox the recommended dosage when recommendations were made is 300 U. Allowing for different prices per vial in each country, the cost per patient per injection for upper limb spasticity was less for Dysport than for Botox in 18 (95% of the 19 countries (mean 17% less across countries. The difference was 20% or higher in nearly half (47% of the countries. Sensitivity analyses considering available "real-world" dosing showed consistent results, with Dysport being less costly than Botox in all 19 countries.Conclusion: Considering costs per patient per injection based on analysis of recommended dosages in the summary of product characteristics, Dysport remains cheaper than Botox in most countries. Thus, when extrapolated to a national level, substantial savings could be realized by using Dysport in the treatment of upper limb spasticity

  4. Ri/leggere Revelli. Metonimia per una presentazione de "Il catalogo per soggetti" di Carlo Revelli Re/reading Revelli. Metonymy for a presentation of Carlo Revelli's "Il catalogo per soggetti"

    Directory of Open Access Journals (Sweden)

    Pino Buizza

    2012-06-01

    Full Text Available The essay traces the story and outlines the structure of the book "Il catalogo per soggetti" written by Carlo Revelli. The book was recently republished, and it looks like a milestone in the history of Italian subject classification.Although facing the change of the tools and the 40 years passed after its first publication, the volume still remains an essential reading in order to understand and practice subject cataloguing.Il saggio ripercorre la storia e la struttura del volume "Il catalogo per soggetti" di Carlo Revelli, recentemente ripubblicato e diventato una pietra miliare nella storia della soggettazione in Italia. Il testo di Revelli, pur dovendo fare i conti con il cambiamento degli strumenti e dopo 40 anni dalla sua prima pubblicazione, rimane fondamentale per la comprensione e la messa in pratica della soggettazione nella catalogazione.

  5. Effects of ventilation rate per person and per floor area on perceived air quality, sick building syndrome symptoms, and decision-making.

    Science.gov (United States)

    Maddalena, R; Mendell, M J; Eliseeva, K; Chan, W R; Sullivan, D P; Russell, M; Satish, U; Fisk, W J

    2015-08-01

    Ventilation rates (VRs) in buildings must adequately control indoor levels of pollutants; however, VRs are constrained by the energy costs. Experiments in a simulated office assessed the effects of VR per occupant on perceived air quality (PAQ), Sick Building Syndrome (SBS) symptoms, and decision-making performance. A parallel set of experiments assessed the effects of VR per unit floor area on the same outcomes. Sixteen blinded healthy young adult subjects participated in each study. Each exposure lasted four hours and each subject experienced two conditions in a within-subject study design. The order of presentation of test conditions, day of testing, and gender were balanced. Temperature, relative humidity, VRs, and concentrations of pollutants were monitored. Online surveys assessed PAQ and SBS symptoms and a validated computer-based tool measured decision-making performance. Neither changing the VR per person nor changing the VR per floor area, had consistent statistically significant effects on PAQ or SBS symptoms. However, reductions in either occupant-based VR or floor-area-based VR had a significant and independent negative impact on most decision-making measures. These results indicate that the changes in VR employed in the study influence performance of healthy young adults even when PAQ and SBS symptoms are unaffected. The study results indicate the importance of avoiding low VRs per person and low VRs per floor area to minimize decrements in cognitive performance. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  6. [Measurement of antimicrobial consumption using DDD per 100 bed-days versus DDD per 100 discharges after the implementation of an antimicrobial stewardship program].

    Science.gov (United States)

    Collado, Roberto; Losa, Juan Emilio; Álvaro, Elena Alba; Toro, Piedad; Moreno, Leonor; Pérez, Montserrat

    2015-12-01

    Monitoring antimicrobial consumption in hospitals is a necessary measure. The indicators commonly employed do not clearly reflect the antibiotic selection pressure. The objective of this study is to evaluate two different methods that analyze antimicrobial consumption based on DDD, per stay and per discharge, before and after the implementation an antimicrobial stewardship program. Comparative pre-post study of antimicrobial consumption with the implementation of an antimicrobial stewardship program using DDD per 100 bed-days and DDD per 100 discharges as indicators. Hospital bed days remained stable and discharges increased slightly along the period of study Antibiotic consumption in DDD per 100 bed-days decreased by 2.5% versus 3.8% when expressed as DDD per 100 discharges. Antifungal consumption decreased by more than 50%. When average hospital stay decreases, reductions in the consumption of antimicrobials with an antimicrobial stewardship program system occur at the expense of reducing the number of patients receiving treatment, while increases occur due to longer durations of treatment.

  7. Per filo e per segno

    DEFF Research Database (Denmark)

    Heltoft, Lars

    2011-01-01

    Analyse af sætningers syntaks og semantik forudsætter viden om deres mulige kontekster, dvs.om deres pragmatik. Analysen af tekster forudsætter på den anden side viden om tegnenes og dermed grammatikkens betydningspotentiale....

  8. Intravenous nutrition. A clinical evaluation of a 50 per cent dextrose in water solution, containing 1 mg. of hydrocortisone per 100 ml.

    Science.gov (United States)

    WESTON, R E; PORT, S J

    1961-01-01

    A 50 per cent dextrose in water solution, containing 1 mg. of hydrocortisone per 100 ml., was used successfully in 70 patients for intravenous nutritional maintenance and repletion. There were no adverse systemic effects during or following 216 infusions. The only undesirable local reaction was the rare occurrence of pain in the arm when the concentrated solutions were given too rapidly. Glycosuria was minimal if the infusion rate did not exceed 0.85 gm. of glucose per kilogram of body weight per hour, particularly if 50 units of insulin were added to each 550 ml. bottle of 50 per cent dextrose. In patients without significantly elevated serum potassium content, 30 mEq. of potassium chloride, acetate or phosphate was added to each bottle to prevent hypokalemia.Preliminary observations suggest that this new solution may be given safely intravenously, without need for cutdowns or plastic catheters, if the needle is carefully inserted and well immobilized in the arm vein and the duration of the infusion is not too prolonged. Further studies on the effect of such high caloric supplementation plus protein hydrolysates in parenteral nutritional repletion and maintenance are indicated.

  9. Contribution Of Human Development Index On Per Capita Income Growth And Poverty Alleviation In Indonesia

    OpenAIRE

    Sudarlan

    2015-01-01

    Abstract The development of a country usually determined by the human development index HDI. Per capita income education and health are the three most important components of human development index. The purpose of this research is to understand the relationship among human development index to income per capita growth and poverty alleviation in Indonesia with cross-section data from 30 provinces period 2002 2011 year. The result of this research were a income per capita growth was not sign...

  10. Evaluation of Instrumentation for Measuring Undissolved Water in Aviation Turbine Fuels per ASTM D3240

    Science.gov (United States)

    2015-11-05

    Undissolved Water in Aviation Turbine Fuels per ASTM D3240 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Joel Schmitigal...water) in Aviation Turbine Fuels per ASTM D3240 15. SUBJECT TERMS fuel, JP-8, aviation fuel, contamination, free water, undissolved water, Aqua-Glo 16...in Aviation Turbine Fuels per ASTM D3240 November 2015 UNCLASSIFIED UNCLASSIFIED Joel Schmitigal 27372 UNCLASSIFIED NOTICES Disclaimers The

  11. Performance evaluation of the Personal Mobility and Manipulation Appliance (PerMMA).

    Science.gov (United States)

    Wang, Hongwu; Xu, Jijie; Grindle, Garrett; Vazquez, Juan; Salatin, Ben; Kelleher, Annmarie; Ding, Dan; Collins, Diane M; Cooper, Rory A

    2013-11-01

    The Personal Mobility and Manipulation Appliance (PerMMA) is a recently developed personal assistance robot created to provide people with severe physical disabilities enhanced assistance in both mobility and manipulation. PerMMA aims to improve functional independence when a personal care attendant is not available on site. PerMMA integrates both a smart powered wheelchair and two dexterous robotic arms to assist its users in completing essential mobility and manipulation tasks during basic and instrumental activities of daily living (ADL). Two user interfaces were developed: a local control interface and a remote operator controller. This paper reports on the evaluation of PerMMA with end users completing basic ADL tasks. Participants with both lower and upper extremity impairments (N=15) were recruited to operate PerMMA and complete up to five ADL tasks in a single session of no more than two hours (to avoid fatigue or frustration of the participants). The performance of PerMMA was evaluated by participants completing ADL tasks with two different control modes: local mode and cooperative control. The users' task completion performance and answers on pre/post-evaluation questionnaires demonstrated not only the ease in learning and usefulness of PerMMA, but also their attitudes toward assistance from advanced technology like PerMMA. As a part of the iterative development process, results of this work will serve as supporting evidence to identify design criteria and other areas for improvement of PerMMA. Copyright © 2013 IPEM. All rights reserved.

  12. Disseny d'una màquina dosificadora per l'alimentació

    OpenAIRE

    Soldevila Dalmau, Guillem

    2015-01-01

    En el present projecte de final de grau es dissenya una màquina industrial per a la dosificació de la mescla de gelat en terrines. Els objectius fixats per a la realització d’aquest projecte són: dissenyar una màquina dosificadora òptima de la mescla de gelat justificant els elements de la màquina, seleccionant el material, els processos de fabricació i muntatge adequats per les peces, escollint els elements normalitzats i de compra adients per la màquina, dissenyant els elements de protecció...

  13. Takistused loova lammutamise teel / Per Högselius ; interv. Kristjan Otsmann

    Index Scriptorium Estoniae

    Högselius, Per

    2006-01-01

    Loova lammutamise teooria uurija innovatsiooniteadlane Per Högselius selgitab, miks on olemasolevasse, kuid iganenud tehnoloogiasse investeerimine innovatsioonile takistuseks ning põhjendab loova lammutamise vajalikkust

  14. Desenvolupament d’una app per Android per realitzar gràfics 2-D de sistemes químics

    OpenAIRE

    Olivers Martorell, Gonçal

    2015-01-01

    Aquest projecte es dedica al disseny i programació d’una aplicació per Android, el sistema operatiu propietat de Google i pensat principalment per dispositius mòbils. El llenguatge de programació que s’utilitza és python, i es fa utilitzant les llibreries obertes de Kivy. Kivy és una eina multi plataforma, és a dir que permet adaptar les aplicacions que es programen als sistemes operatius d’Android i iOS. En aquest treball es tracta detalladament com fer l’exportació a Android,...

  15. Einfluß von Persönlichkeitsmerkmalen gemessen anhand des Freiburger Persönlichkeitsinventars (FPI) auf postanästhesiologisches Erbrechen

    OpenAIRE

    Löbmann, Ulrich B. H.

    2003-01-01

    Zusammenfassung:In der vorliegenden prospektiven, randomisierten und mehrfach stratifizierten, doppelblinden, kontrollierten Studie mit faktoriellem Design sollte analysiert werden, ob die Ausprägung eines Persönlichkeitsmerkmals, welches mit dem Freiburger Persönlichkeitsinventar (FPI) erhoben wurde, einen direkten Einfluß auf PÜ&E hat und welchen Stellenwert ein möglicher Einfluß auf das PÜ&E-Risiko im Kontext der sonstigen Einflußfaktoren hat. Insgesamt konnten 1180 Teilnehmer in die Studi...

  16. PER3 polymorphism predicts cumulative sleep homeostatic but not neurobehavioral changes to chronic partial sleep deprivation.

    Directory of Open Access Journals (Sweden)

    Namni Goel

    2009-06-01

    Full Text Available The variable number tandem repeat (VNTR polymorphism 5-repeat allele of the circadian gene PERIOD3 (PER3(5/5 has been associated with cognitive decline at a specific circadian phase in response to a night of total sleep deprivation (TSD, relative to the 4-repeat allele (PER3(4/4. PER3(5/5 has also been related to higher sleep homeostasis, which is thought to underlie this cognitive vulnerability. To date, no study has used a candidate gene approach to investigate the response to chronic partial sleep deprivation (PSD, a condition distinct from TSD and one commonly experienced by millions of people on a daily and persistent basis. We evaluated whether the PER3 VNTR polymorphism contributed to cumulative neurobehavioral deficits and sleep homeostatic responses during PSD.PER3(5/5 (n = 14, PER3(4/5 (n = 63 and PER3(4/4 (n = 52 healthy adults (aged 22-45 y demonstrated large, but equivalent cumulative decreases in cognitive performance and physiological alertness, and cumulative increases in sleepiness across 5 nights of sleep restricted to 4 h per night. Such effects were accompanied by increasing daily inter-subject variability in all groups. The PER3 genotypes did not differ significantly at baseline in habitual sleep, physiological sleep structure, circadian phase, physiological sleepiness, cognitive performance, or subjective sleepiness, although during PSD, PER3(5/5 subjects had slightly but reliably elevated sleep homeostatic pressure as measured physiologically by EEG slow-wave energy in non-rapid eye movement sleep compared with PER3(4/4 subjects. PER3 genotypic and allelic frequencies did not differ significantly between Caucasians and African Americans.The PER3 VNTR polymorphism was not associated with individual differences in neurobehavioral responses to PSD, although it was related to one marker of sleep homoeostatic response during PSD. The comparability of PER3 genotypes at baseline and their equivalent inter-individual vulnerability

  17. PDF and cAMP enhance PER stability in Drosophila clock neurons.

    Science.gov (United States)

    Li, Yue; Guo, Fang; Shen, James; Rosbash, Michael

    2014-04-01

    The neuropeptide PDF is important for Drosophila circadian rhythms: pdf(01) (pdf-null) animals are mostly arrhythmic or short period in constant darkness and have an advanced activity peak in light-dark conditions. PDF contributes to the amplitude, synchrony, as well as the pace of circadian rhythms within clock neurons. PDF is known to increase cAMP levels in PDR receptor (PDFR)-containing neurons. However, there is no known connection of PDF or of cAMP with the Drosophila molecular clockworks. We discovered that the mutant period gene per(S) ameliorates the phenotypes of pdf-null flies. The period protein (PER) is a well-studied repressor of clock gene transcription, and the per(S) protein (PERS) has a markedly short half-life. The result therefore suggests that the PDF-mediated increase in cAMP might lengthen circadian period by directly enhancing PER stability. Indeed, increasing cAMP levels and cAMP-mediated protein kinase A (PKA) activity stabilizes PER, in S2 tissue culture cells and in fly circadian neurons. Adding PDF to fly brains in vitro has a similar effect. Consistent with these relationships, a light pulse causes more prominent PER degradation in pdf(01) circadian neurons than in wild-type neurons. The results indicate that PDF contributes to clock neuron synchrony by increasing cAMP and PKA, which enhance PER stability and decrease clock speed in intrinsically fast-paced PDFR-containing clock neurons. We further suggest that the more rapid degradation of PERS bypasses PKA regulation and makes the pace of clock neurons more uniform, allowing them to avoid much of the asynchrony caused by the absence of PDF.

  18. Nou professorat d'educació secundària per a noves realitats. Formació inicial i període llindar.

    Directory of Open Access Journals (Sweden)

    Josep-L. Boix-Peinado

    2008-12-01

    Full Text Available Aquesta investigació s’inspira en el paradigma emergent, síntesi de tots els esforços paradigmàtics i metodològics anteriors. La metodologia utilitzada ha estat participativa i holística i, per a això, hem treballat amb diferents instruments: qüestionaris, entrevistes semiestructurades, grups de discussió, històries de vida i qüestionaris DAFO. Primerament, ens vam proposar descobrir les necessitats del professorat en els inicis professionals, així com definir els processos de desenvolupament de les competències claus de bones pràctiques docents que són necessàries per afrontar i exercir en el futur amb una docència de qualitat. Les aportacions dels alumnes dels cursos CAP (Certificat d’Aptitud Pedagògica i CCP (Curs de Qualificació Pedagògica, així com de l’alumnat d’educació secundària, el professorat, les organitzacions sindicals, les associacions de pares i mares i el professorat de diferents cursos de formació inicial, són les fonts de la informació des de les quals hem obtingut les dades per repensar sobre la formació inicial i el període llindar del professorat d’educació secundària.

  19. Streblidae de murciélagos de Lima: dos citas nuevas para Perú Streblidae of bats from Lima: two new cites for Perú

    Directory of Open Access Journals (Sweden)

    Guillermo L. Claps

    2005-07-01

    Full Text Available Se presentan nuevos registros de Streblidae para el departamento Lima (Perú, que parasitan a tres especies de murciélagos de la familia Phyllostomidae: Anoura geoffroyi Gray, Carollia perspicillata (Linneo y Desmodus rotundus (Geoffroy. Se amplía la distribución geográfica de Anastrebla modestini Wenzel, Aspidoptera falcata Wenzel, Exastinion clovisi (Pessôa & Guimarães, Megistopoda aranea (Coquillett, Speiseria ambigua Kessel y Strebla wiedemanni Kolenati (Diptera, Streblidae, dado que se registran por primera vez en el departamento, y A. modestini y E. clovisi se mencionan por primera vez en Perú.New distributional records for bat ectoparasites (Streblidae, are presented for the Department of Lima (Perú. They were reported as collected on bats of the family Phyllostomidae: Anoura geoffroyi Gray, Carollia perspicillata (Linneo and Desmodus rotundus (Geoffroy. The distribution of Anastrebla modestini Wenzel, Aspidoptera falcata Wenzel, Exastinion clovisi (Pessôa & Guimarães, Megistopoda aranea (Coquillett, Speiseria ambigua Kessel and Strebla wiedemanni Kolenati (Diptera, Streblidae, is extended to the Department of Lima, and Anastrebla modestini and Exastinion clovisi are added to the fauna of Perú.

  20. Per tree estimates with n-tree distance sampling: an application to increment core data

    Science.gov (United States)

    Thomas B. Lynch; Robert F. Wittwer

    2002-01-01

    Per tree estimates using the n trees nearest a point can be obtained by using a ratio of per unit area estimates from n-tree distance sampling. This ratio was used to estimate average age by d.b.h. classes for cottonwood trees (Populus deltoides Bartr. ex Marsh.) on the Cimarron National Grassland. Increment...

  1. PerPos: A Platform Providing Cloud Services for Pervasive Positioning

    DEFF Research Database (Denmark)

    Blunck, Henrik; Godsk, Torben; Grønbæk, Kaj

    2010-01-01

    -based building model manager that allows users to manage building models stored in the PerPos cloud for annotation, logging, and navigation purposes. A core service in the PerPos platform is sensor fusion for positioning that makes it seamless and efficient to combine a rich set of position sensors to obtain...

  2. Effect of inter-row spacing and plant stand per hill on the yield of ...

    African Journals Online (AJOL)

    F.ield experiments were conducted to determine whether change in inter-row spacing and plant stand per blllaffeds grain yreld of the new improved cowpea lines. Yield was used to determined the best inter-row spacing and plant stand per bill for three new improved high yieldlng cowpea Vigna unguicuJata lines at Serere ...

  3. GIUSEPPE DE ROSA, Metodo per pianisti accompagnatori della danza, Milano, Suvini Zerboni, 2010

    Directory of Open Access Journals (Sweden)

    Chiara Sintoni

    2014-12-01

    Full Text Available Il volume di Giuseppe De Rosa è al contempo un agile metodo teorico-pratico per la formazione del pianista accompagnatore della danza classica e un sussidio didattico per la sua attività in situazione. Frutto dell’esperienza pluriennale dell’autore, colma un vuoto nella pubblicistica italiana dedicata all’argomento.

  4. Desenvolupament d'una App de Google Chrome per a la definició de requisits

    OpenAIRE

    Bertrán Hernández, Núria

    2016-01-01

    App de chrome per què enginyers de requisits puguin accedir al servei PABRE per editar especificacions de requisits a partir dels patrons emmagatzemats en PABRE. Chome App to allow requeriments engineers to access the PABRE services to edit requirements specifications, based on patterns stored in PABRE.

  5. Comparative evaluation of ovarian structures in cattle by palpation per rectum, ultrasonography and plasma progesterone concentration.

    Science.gov (United States)

    Ribadu, A Y; Ward, W R; Dobson, H

    1994-11-05

    The aims of this study were to determine the relationship between the ultrasonographic determination of corpora lutea and the plasma progesterone profile of cyclic cows during an oestrous cycle, and to compare the accuracy of detection of normal and abnormal ovarian structures by ultrasonography and palpation per rectum, based on the plasma progesterone profile. The ovaries of six lactating cyclic dairy cows were scanned and blood samples were obtained three times a week for one month. There was a high correlation (r = 0.85) between the diameter of the corpus luteum and the plasma progesterone concentration, but on days -3 and -2 (oestrus = day 0) the diameter was the same as mid-luteal values but it was functionally inactive (plasma progesterone cows by using the plasma progesterone concentration and the dissection of ovaries post mortem as standards. The sensitivity, specificity and positive predictive value of palpation for identifying mid-cyclic corpora lutea were 85 per cent, 95.7 per cent and 89.5 per cent, respectively. Ultrasonography had a sensitivity of 95 per cent, a specificity of 100 per cent and a positive predictive value of 100 per cent. Twenty-nine cows were diagnosed by palpation per rectum as having either follicular or luteal cysts. During ultrasonography, an ovarian cyst was defined as a non-echogenic structure at least 5 mm in diameter.(ABSTRACT TRUNCATED AT 250 WORDS)

  6. Biblioteca de components per aplicacions mòbils iOS

    OpenAIRE

    Ganduxé Pregona, Oriol

    2013-01-01

    En aquest projecte es desenvolupa un sistema que permet emmagatzemar, en una biblioteca centralitzada, blocs funcionals de programari iOS (iPhone/iPod Operative System) per facilitar i accelerar el procés de desenvolupament de productes nous, per equips relativament grans i deslocalitzats.

  7. Measuring bitterbrush seed production on plants with variable crown density...complete counts per plant suggested

    Science.gov (United States)

    Donald W. Seegrist; Donald L. Neal; Richard L. Hubbard

    1966-01-01

    A sampling study was made of the number of bitterbrush seeds per trap from plots in northeastern California. The count per trap had a large variation for each plant. This variation was not reduced to an acceptable low level by grouping the seed traps according to their position relative to the plant crown. In the absence of additional information, it is recommended...

  8. Bounding the per-protocol effect in randomized trials: An application to colorectal cancer screening

    NARCIS (Netherlands)

    S.A. Swanson (Sonja); Holme (Øyvind); M. Løberg (Magnus); M. Kalager (Mette); M. Bretthauer (Michael); G. Hoff (G.); E. Aas (Eline); M.A. Hernán (M.)

    2015-01-01

    textabstractBackground: The per-protocol effect is the effect that would have been observed in a randomized trial had everybody followed the protocol. Though obtaining a valid point estimate for the per-protocol effect requires assumptions that are unverifiable and often implausible, lower and upper

  9. Circadian Rhythms and Breast Cancer: The Role of Per2 in Doxorubicin-Induced Cell Death.

    Science.gov (United States)

    Mitchell, Megan I; Engelbrecht, Anna-Mart

    2015-01-01

    Mammalian circadian rhythms form an integral physiological system allowing for the synchronisation of all metabolic processes to daily light/dark cycles, thereby optimising their efficacy. Circadian disruptions have been implicated in the onset and progression of various cancers, including those arising in the breast. Several links between the circadian protein Per2 and DNA damage responses exist. Aberrant Per2 expression results in potent downstream effects on both cell cycle and apoptotic targets, suggestive of a tumour suppressive role for Per2. Due to the severe dose limiting side effects associated with current chemotherapeutic strategies, including the use of doxorubicin, a need for more effective adjuvant therapies to increase cancer cell susceptibility has arisen. This study was therefore aimed at characterizing the role of Per2 in normal breast epithelia (MCF-12A) and in ER(-) breast cancer cells (MDA-MB-231) and also at determining the role of Per2 in doxorubicin-induced cell death. In both cell lines Per2 protein expression displayed a 24-hour circadian rhythm in both cell lines. Per2 was located predominantly in the cytoplasm, with nuclear localization observed with lower cytoplasmic fluorescent intensities. Our results show that Per2 silencing effectively sensitizes the chemoresistant MDA-MB-231 breast cancer cells to the cytotoxic effects of doxorubicin.

  10. 76 FR 19710 - Tobacco Transition Payment Program; Cigar and Cigarette Per Unit Assessments; Correction

    Science.gov (United States)

    2011-04-08

    ... Payment Program; Cigar and Cigarette Per Unit Assessments; Correction AGENCY: Commodity Credit Corporation... correction to the Request for Comments titled ``Tobacco Transition Payment Program; Cigar and Cigarette Per... correcting an inaccurate statement about the possible consequences of an alternative assessment methodology...

  11. CityLog, verso nuove soluzioni per la distribuzione urbana delle merci

    Directory of Open Access Journals (Sweden)

    Saverio Zuccotti

    2010-07-01

    Full Text Available La logistica urbana rappresenta oggi una delle principali sfide per una mobilità sostenibile. La distribuzione delle merci in città paga infatti in competitività quei problemi di cui è in parte responsabile: traffico, inquinamento, incidenti etc. Negli ultimi anni la sensibilità su questi aspetti di sostenibilità ambientale è cresciuta in maniera netta, e a livello europeo molta strada è stata fatta per predisporre le risposte più adeguate. Il progetto europeo CityLog, finanziato nell’ambito del Settimo Programma Quadro, vede oggi collaborare diciotto partner europei coordinati dal Centro Ricerche Fiat per migliorare la logistica urbana agendo lungo tre direttrici: •\tservizi telematici orientati alla logistica, per dare un contributo decisivo al miglioramento della pianificazione delle missioni utilizzando strumenti per il routing ottimizzato dei veicoli e il supporto informativo costante agli autisti dei veicoli; •\tsoluzioni a bordo veicolo, che rappresentano un fattore chiave per aumentare la flessibilità operativa di camion e furgoni; •\tunità di carico innovative, accuratamente progettate per essere utilizzate su veicoli diversi in missioni diverse. Ne deriva pertanto una famiglia di container compatti con un layout interno riconfigurabile così da poter essere utilizzati per scopi diversi.

  12. 7 CFR 1205.512 - Collecting handlers and time of collection of $1 per bale assessment.

    Science.gov (United States)

    2010-01-01

    ... bale assessment. 1205.512 Section 1205.512 Agriculture Regulations of the Department of Agriculture....512 Collecting handlers and time of collection of $1 per bale assessment. Collecting handlers and the time of collecting the $1 per bale assessment shall be as follows: (a) Except as provided in paragraph...

  13. 77 FR 61423 - Notice of Adjustment of Statewide Per Capita Impact Indicator

    Science.gov (United States)

    2012-10-09

    ... SECURITY Federal Emergency Management Agency Notice of Adjustment of Statewide Per Capita Impact Indicator... statewide per capita impact indicator under the Public Assistance program for disasters declared on or after... indicator under the Public Assistance program to reflect changes in the Consumer Price Index for All Urban...

  14. 76 FR 63936 - Notice of Adjustment of Statewide Per Capita Impact Indicator

    Science.gov (United States)

    2011-10-14

    ... SECURITY Federal Emergency Management Agency Notice of Adjustment of Statewide Per Capita Impact Indicator... statewide per capita impact indicator under the Public Assistance program for disasters declared on or after... indicator under the Public Assistance program to reflect changes in the Consumer Price Index for All Urban...

  15. 77 FR 61011 - Notice of Adjustment of Countywide Per Capita Impact Indicator

    Science.gov (United States)

    2012-10-05

    ... SECURITY Federal Emergency Management Agency Notice of Adjustment of Countywide Per Capita Impact Indicator... countywide per capita impact indicator under the Public Assistance program for disasters declared on or after... capita indicator to evaluate the impact of the disaster at the county level. FEMA will adjust the...

  16. 75 FR 62135 - Notice of Adjustment of Statewide Per Capita Impact Indicator

    Science.gov (United States)

    2010-10-07

    ... SECURITY Federal Emergency Management Agency Notice of Adjustment of Statewide Per Capita Impact Indicator... statewide per capita impact indicator under the Public Assistance program for disasters declared on or after... indicator under the Public Assistance program to reflect changes in the Consumer Price Index for All Urban...

  17. 78 FR 64231 - Notice of Adjustment of Countywide Per Capita Impact Indicator

    Science.gov (United States)

    2013-10-28

    ... SECURITY Federal Emergency Management Agency Notice of Adjustment of Countywide Per Capita Impact Indicator... countywide per capita impact indicator under the Public Assistance program for disasters declared on or after... capita indicator to evaluate the impact of the disaster at the county level. FEMA will adjust the...

  18. Nuevos bivalvos para el Perú en Bahía Independencia

    Directory of Open Access Journals (Sweden)

    Oswaldo Cornejo

    2013-06-01

    Full Text Available Se registran por primera vez para el Perú las siguientes especies de bivalvos Nucula (Nucula pisum Sowerby I, 1833, y Lyonsia delicata Marincovich, 1973, colectadas en Bahía Independencia, Pisco, Perú, en el 2002.

  19. KPNB1 mediates PER/CRY nuclear translocation and circadian clock function.

    Science.gov (United States)

    Lee, Yool; Jang, A Reum; Francey, Lauren J; Sehgal, Amita; Hogenesch, John B

    2015-08-29

    Regulated nuclear translocation of the PER/CRY repressor complex is critical for negative feedback regulation of the circadian clock of mammals. However, the precise molecular mechanism is not fully understood. Here, we report that KPNB1, an importin β component of the ncRNA repressor of nuclear factor of activated T cells (NRON) ribonucleoprotein complex, mediates nuclear translocation and repressor function of the PER/CRY complex. RNAi depletion of KPNB1 traps the PER/CRY complex in the cytoplasm by blocking nuclear entry of PER proteins in human cells. KPNB1 interacts mainly with PER proteins and directs PER/CRY nuclear transport in a circadian fashion. Interestingly, KPNB1 regulates the PER/CRY nuclear entry and repressor function, independently of importin α, its classical partner. Moreover, inducible inhibition of the conserved Drosophila importin β in lateral neurons abolishes behavioral rhythms in flies. Collectively, these data show that KPNB1 is required for timely nuclear import of PER/CRY in the negative feedback regulation of the circadian clock.

  20. Effects of different per translational kinetics on the dynamics of a core circadian clock model.

    Directory of Open Access Journals (Sweden)

    Paula S Nieto

    Full Text Available Living beings display self-sustained daily rhythms in multiple biological processes, which persist in the absence of external cues since they are generated by endogenous circadian clocks. The period (per gene is a central player within the core molecular mechanism for keeping circadian time in most animals. Recently, the modulation PER translation has been reported, both in mammals and flies, suggesting that translational regulation of clock components is important for the proper clock gene expression and molecular clock performance. Because translational regulation ultimately implies changes in the kinetics of translation and, therefore, in the circadian clock dynamics, we sought to study how and to what extent the molecular clock dynamics is affected by the kinetics of PER translation. With this objective, we used a minimal mathematical model of the molecular circadian clock to qualitatively characterize the dynamical changes derived from kinetically different PER translational mechanisms. We found that the emergence of self-sustained oscillations with characteristic period, amplitude, and phase lag (time delays between per mRNA and protein expression depends on the kinetic parameters related to PER translation. Interestingly, under certain conditions, a PER translation mechanism with saturable kinetics introduces longer time delays than a mechanism ruled by a first-order kinetics. In addition, the kinetic laws of PER translation significantly changed the sensitivity of our model to parameters related to the synthesis and degradation of per mRNA and PER degradation. Lastly, we found a set of parameters, with realistic values, for which our model reproduces some experimental results reported recently for Drosophila melanogaster and we present some predictions derived from our analysis.

  1. Does increasing milk yield per cow reduce greenhouse gas emissions? A system approach.

    Science.gov (United States)

    Zehetmeier, M; Baudracco, J; Hoffmann, H; Heißenhuber, A

    2012-01-01

    Milk yield per cow has continuously increased in many countries over the last few decades. In addition to potential economic advantages, this is often considered an important strategy to decrease greenhouse gas (GHG) emissions per kg of milk produced. However, it should be considered that milk and beef production systems are closely interlinked, as fattening of surplus calves from dairy farming and culled dairy cows play an important role in beef production in many countries. The main objective of this study was to quantify the effect of increasing milk yield per cow on GHG emissions and on other side effects. Two scenarios were modelled: constant milk production at the farm level and decreasing beef production (as co-product; Scenario 1); and both milk and beef production kept constant by compensating the decline in beef production with beef from suckler cow production (Scenario 2). Model calculations considered two types of production unit (PU): dairy cow PU and suckler cow PU. A dairy cow PU comprises not only milk output from the dairy cow, but also beef output from culled cows and the fattening system for surplus calves. The modelled dairy cow PU differed in milk yield per cow per year (6000, 8000 and 10 000 kg) and breed. Scenario 1 resulted in lower GHG emissions with increasing milk yield per cow. However, when milk and beef outputs were kept constant (Scenario 2), GHG emissions remained approximately constant with increasing milk yield from 6000 to 8000 kg/cow per year, whereas further increases in milk yield (10 000 kg milk/cow per year) resulted in slightly higher (8%) total GHG emissions. Within Scenario 2, two different allocation methods to handle co-products (surplus calves and beef from culled cows) from dairy cow production were evaluated. Results showed that using the 'economic allocation method', GHG emissions per kg milk decreased with increasing milk yield per cow per year, from 1.06 kg CO2 equivalents (CO2eq) to 0.89 kg CO2eq for the 6000 and

  2. Circadian rhythm genes CLOCK and PER3 polymorphisms and morning gastric motility in humans.

    Directory of Open Access Journals (Sweden)

    Mitsue Yamaguchi

    Full Text Available Clock genes regulate circadian rhythm and are involved in various physiological processes, including digestion. We therefore investigated the association between the CLOCK 3111T/C single nucleotide polymorphism and the Period3 (PER3 variable-number tandem-repeat polymorphism (either 4 or 5 repeats 54 nt in length with morning gastric motility.Lifestyle questionnaires and anthropometric measurements were performed with 173 female volunteers (mean age, 19.4 years. Gastric motility, evaluated by electrogastrography (EGG, blood pressure, and heart rate levels were measured at 8:30 a.m. after an overnight fast. For gastric motility, the spectral powers (% normal power and dominant frequency (DF, peak of the power spectrum of the EGG were evaluated. The CLOCK and PER3 polymorphisms were determined by polymerase chain reaction (PCR restriction fragment length polymorphism analysis.Subjects with the CLOCK C allele (T/C or C/C genotypes: n = 59 showed a significantly lower DF (mean, 2.56 cpm than those with the T/T genotype (n = 114, 2.81 cpm, P < 0.05. Subjects with the longer PER3 allele (PER34/5 or PER35/5 genotypes: n = 65 also showed a significantly lower DF (2.55 cpm than those with the shorter PER34/4 genotype (n = 108, 2.83 cpm, P < 0.05. Furthermore, subjects with both the T/C or C/C and PER34/5 or PER35/5 genotypes showed a significantly lower DF (2.43 cpm, P < 0.05 than subjects with other combinations of the alleles (T/T and PER34/4 genotype, T/C or C/C and PER34/4 genotypes, and T/T and PER34/5 or PER35/5 genotypes.These results suggest that minor polymorphisms of the circadian rhythm genes CLOCK and PER3 may be associated with poor morning gastric motility, and may have a combinatorial effect. The present findings may offer a new viewpoint on the role of circadian rhythm genes on the peripheral circadian systems, including the time-keeping function of the gut.

  3. The Effect of Different Photoperiods in Circadian Rhythms of Per3 Knockout Mice

    Directory of Open Access Journals (Sweden)

    D. S. Pereira

    2014-01-01

    Full Text Available The aim of this study was to analyse the circadian behavioural responses of mice carrying a functional knockout of the Per3 gene (Per3−/− to different light : dark (L : D cycles. Male adult wild-type (WT and Per3−/− mice were kept under 12-hour light : 12-hour dark conditions (12L : 12D and then transferred to either a short or long photoperiod and subsequently released into total darkness. All mice were exposed to both conditions, and behavioural activity data were acquired through running wheel activity and analysed for circadian characteristics during these conditions. We observed that, during the transition from 12L : 12D to 16L : 8D, Per3−/− mice take approximately one additional day to synchronise to the new L : D cycle compared to WT mice. Under these long photoperiod conditions, Per3−/− mice were more active in the light phase. Our results suggest that Per3−/− mice are less sensitive to light. The data presented here provides further evidence that Per3 is involved in the suppression of behavioural activity in direct response to light.

  4. Direct and specific effect of sevoflurane anesthesia on rat Per2 expression in the suprachiasmatic nucleus.

    Directory of Open Access Journals (Sweden)

    Megumi Anzai

    Full Text Available BACKGROUND: Our previous studies revealed that application of the inhalation anesthetic, sevoflurane, reversibly repressed the expression of Per2 in the mouse suprachiasmatic nucleus (SCN. We aimed to examine whether sevoflurane directly affects the SCN. METHODS: We performed in vivo and in vitro experiments to investigate rat Per2 expression under sevoflurane-treatment. The in vivo effects of sevoflurane on rPer2 expression were examined by quantitative in situ hybridization with a radioactively-labeled cRNA probe. Additionally, we examined the effect of sevoflurane anesthesia on rest/activity rhythms in the rat. In the in vitro experiments, we applied sevoflurane to SCN explant cultures from Per2-dLuc transgenic rats, and monitored luciferase bioluminescence, representing Per2 promoter activity. Bioluminescence from two peripheral organs, the kidney cortex and the anterior pituitary gland, were also analyzed. RESULTS: Application of sevoflurane in rats significantly suppressed Per2 expression in the SCN compared with untreated animals. We observed no sevoflurane-induced phase-shift in the rest/activity rhythms. In the in vitro experiments, the intermittent application of sevoflurane repressed the increase of Per2-dLuc luminescence and led to a phase delay in the Per2-dLuc luminescence rhythm. Sevoflurane treatment did not suppress bioluminescence in the kidney cortex or the anterior pituitary gland. CONCLUSION: The suppression of Per2-dLuc luminescence by sevoflurane in in vitro SCN cultures isolated from peripheral inputs and other nuclei suggest a direct action of sevoflurane on the SCN itself. That sevoflurane has no such effect on peripheral organs suggests that this action might be mediated through a neuron-specific cellular mechanism or a regulation of the signal transduction between neurons.

  5. Sistema de visió omnidireccional per a vols amb drons

    OpenAIRE

    Bracero Hernandez, David

    2017-01-01

    En aquest document es presenta un sistema de visió estèreo binocular basat en dues càmeres idèntiques amb lents d'ull de peix de 220 graus. Posicionades respecte un mateix eix vertical, però enfocant en sentits oposats, aquestes càmeres permeten obtenir dos hemisferis de 360 per 220 graus, corresponents a la meitat superior i inferior d'una esfera completa. D'aquesta manera s'obté una regió comuna a ambdues imatges, fet que permet obtenir disparitat entre elles i, per tant, visió estereoscòpi...

  6. Nou model animal experimental per a l'artrosi precoç

    OpenAIRE

    Faig Martí, Jordi

    2003-01-01

    Introducció: Les malalties que afecten el sistema locomotor produeixen una gran limitació en la funcionalitat de la població, especialment en les edats avançades de la vida. Per progressar en el coneixement de l'artrosi es va engegar el treball que presentem, com a model experimental que permetés estudiar tractaments en un model animal per a les fases inicials d'aquesta malaltia.Material i Mètode: Per portar a terme l'estudi es van utilitzar 15 bens adults de 3 anys d'edat. En condicions d'as...

  7. Estudi de viabilitat de la tecnologia CUDA per l'acceleració de processos

    OpenAIRE

    Sánchez Castellano, Rubén

    2012-01-01

    Aquest projecte estudia la viabilitat de l’ús de la tecnologia CUDA del fabricant NVIDIA per a accelerar l’execució de processos que tracten un gran volum de dades. Durant el desenvolupament del projecte s’analitza els cost de la modificació del codi font original per a CPU del software per adaptar-lo a la tecnologia CUDA adaptant dues aplicacions a aquesta tecnologia: la biblioteca de vídeo libvpx i el xifrador AES. A més a més, també s’analitza el temps d’execució i ...

  8. Detecció de text ofuscat per evitar els detectors de plagi

    OpenAIRE

    Avila Ferré, Victor

    2016-01-01

    En l'àmbit acadèmic i professional hi ha una corrent molt àmplia de plagis en els documents, atemptant contra la propietat intel·lectual de l'autor original. Per combatre'ls existeixen eines anomenades detectors de plagi, que permeten analitzar documents amb possibles irregularitats. Aquests detectors tenen una alta probabilitat de detecció, però poden ser enganyats utilitzant els anomenats mètodes d'ofuscació. Els mètodes d'ofuscació permeten al plagiador utilitzar tècniques no visibles per ...

  9. Vídeo de presentació del Campus per la Pau

    OpenAIRE

    Campus per la Pau

    2010-01-01

    Eduard Vinyamata, el director del Campus per la Pau, presenta la universitat de les ONG, la iniciativa solidària de la Universitat Oberta de Catalunya. El Campus per la Pau té el propòsit de contribuir a la pau, a la solidaritat amb les persones i societats menys afavorides, per la cooperació en el desenvolupament, l'ajut humanitari i la sostenibilitat, i es fonamenta en principis ètics bàsics com la Declaració universal dels drets humans i la Carta de la terra Eduard Vinyamata, el directo...

  10. The one laptop per Child (OLPC) computer for health clinics in developing countries.

    Science.gov (United States)

    Fontelo, Paul; Liu, Fang; Zhang, Kai; Ackerman, Michael; Tolentino, Herman

    2008-11-06

    The 'One Laptop per Child' or XO computer was developed as an education tool for children in developing countries around the world. We wanted to know whether it could also be used to access knowledge sources at the NLM formatted for low bandwidth environments. We report on our experience in using the OLPC computer as a gateway to NLM databases (MEDLINE/PubMed), a virtual slide collection and electronic health records. Based on our experiments, we believe that the OLPC computer can also be a 'One Laptop per Clinic' or a 'One Laptop per Doc' computer.

  11. Improvement of training process of powerlifters on the basis of an interactive program "PersTrainer"

    Directory of Open Access Journals (Sweden)

    Volodymyr Ashanin

    2017-12-01

    Full Text Available Purpose: to develop and scientifically substantiate the program "PersTrainer" for improving the training process of powerlifters. Material & Methods: the study involved the powerlifters of 16–18 years. The following research methods were used: analysis and generalization of the literary sources and data of the Internet, pedagogical observation and the method of information modeling. Results: the interactive program "PersTrainer" is developed and theoretically justified, which allows individually calculating the training load in different training cycles. Conclusion: it is possible to plan training loads on the basis of individually proposed exercise complexes, which are presented in the interactive program "PersTrainer".

  12. Del “Perón Vuelve” al día que Perón volvió. Ezeiza 1973, percepciones de un regreso

    Directory of Open Access Journals (Sweden)

    Fonte, Leonardo Mario

    2014-12-01

    Full Text Available Resumen Este trabajo se ocupa de analizar una serie de cuestiones que se desprenden de los sucesos ocurridos en Ezeiza, el 20 de junio de 1973, en el contexto de la vigilia por el regreso a la Argentina de Juan Domingo Perón. En tal sentido, en primer lugar se pretenderá definir si la conceptualización “masacre”, semánticamente, mantiene un correlato con los eventos desarrollados durante esa jornada. En segundo lugar, se buscará analizar si es posible aseverar, que la izquierda peronista en su conjunto fue la víctima ingenua de una matanza perpetrada intencionalmente para desplazar a Cámpora y copar el poder. Por último, se tratará de examinar cómo el 20 de junio de 1973, se evidenciaron las contradicciones existentes entre la conducción de Montoneros y Perón, y cómo estas diferencias acabaron cristalizándose en los incidentes ocurridos. Abstract This work focuses on analyzing a series of issues that took place during June 20th 1973 in Ezeiza in the context of the eve for the return of Juan Domingo Perón to Argentina. In first place, it will be attempted to define if the concept of “Massacre”, in a semantic way, keeps a correlation with the events that developed during that day. Secondly, an analysis will be made to see if it is possible to asseverate that the “Peronist left-wing movement” was an innocent victim of a bloodbath made intentionally to displace Cámpora and take the power. Finally, we will examine how on June 20th 1973 the contradictions between Montoneros and Perón became evident and how these differences, in the end, were reflected in the incidents.

  13. miR-34a-dependent overexpression of Per1 decreases cholangiocarcinoma growth.

    Science.gov (United States)

    Han, Yuyan; Meng, Fanyin; Venter, Julie; Wu, Nan; Wan, Ying; Standeford, Holly; Francis, Heather; Meininger, Cynthia; Greene, John; Trzeciakowski, Jerome P; Ehrlich, Laurent; Glaser, Shannon; Alpini, Gianfranco

    2016-06-01

    Disruption of circadian rhythm is associated with cancer development and progression. MicroRNAs (miRNAs) are a class of small non-coding RNAs that trigger mRNA translation inhibition. We aimed to evaluate the role of Per1 and related miRNAs in cholangiocarcinoma growth. The expression of clock genes was evaluated in human cholangiocarcinoma tissue arrays and cholangiocarcinoma lines. The rhythmic expression of clock genes was evaluated in cholangiocarcinoma cells and H69 (non-malignant cholangiocytes) by qPCR. We measured cell proliferation, cell cycle and apoptosis in Mz-ChA-1 cells after Per1 overexpression. We examined tumor growth in vivo after injection of Per1 overexpressing cells. We verified miRNAs that targets Per1. The circadian rhythm of miR-34a was evaluated in cholangiocarcinoma and H69 cells. We evaluated cell proliferation, apoptosis and invasion after inhibition of miR-34a in vitro, and the potential molecular mechanisms by mRNA profiling after overexpression of Per1. Expression of Per1 was decreased in cholangiocarcinoma. The circadian rhythm of Per1 expression was lost in cholangiocarcinoma cells. Decreased cell proliferation, lower G2/M arrest, and enhanced apoptosis were shown in Per1 overexpressing cells. An in vivo study revealed decreased tumor growth, decreased proliferation, angiogenesis and metastasis after overexpressing Per1. Per1 was verified as a target of miR-34a. miR-34a was rhythmically expressed in cholangiocarcinoma cells and H69. The inhibition of miR-34a decreased proliferation, migration and invasion in cholangiocarcinoma cells. mRNA profiling has shown that overexpression of Per1 inhibits cell growth through regulation of multiple cancer-related pathways, such as cell cycle, cell growth and apoptosis pathways. Disruption of circadian rhythms of clock genes contribute to the malignant phenotypes of human cholangiocarcinoma. The current study is about how biological clock and its regulators affect the bile duct tumor growth. The

  14. Diurnal preference, mood and the response to morning light in relation to polymorphisms in the human clock gene PER3.

    Science.gov (United States)

    Turco, M; Biscontin, A; Corrias, M; Caccin, L; Bano, M; Chiaromanni, F; Salamanca, M; Mattei, D; Salvoro, C; Mazzotta, G; De Pittà, C; Middleton, B; Skene, D J; Montagnese, S; Costa, R

    2017-07-31

    PER3 gene polymorphisms have been associated with differences in human sleep-wake phenotypes, and sensitivity to light. The aims of this study were to assess: i) the frequency of allelic variants at two PER3 polymorphic sites (rs57875989 length polymorphism: PER3 4, PER3 5; rs228697 SNP: PER3 C, PER3 G) in relation to sleep-wake timing; ii) the effect of morning light on behavioural/circadian variables in PER3 4 /PER3 4 and PER3 5 /PER3 5 homozygotes. 786 Caucasian subjects living in Northern Italy donated buccal DNA and completed diurnal preference, sleep quality/timing and sleepiness/mood questionnaires. 19 PER3 4 /PER3 4 and 11 PER3 5 /PER3 5 homozygotes underwent morning light administration, whilst monitoring sleep-wake patterns and the urinary 6-sulphatoxymelatonin (aMT6s) rhythm. No significant relationship was observed between the length polymorphism and diurnal preference. By contrast, a significant association was observed between the PER3 G variant and morningness (OR = 2.10), and between the PER3 G-PER3 4 haplotype and morningness (OR = 2.19), for which a mechanistic hypothesis is suggested. No significant differences were observed in sleep timing/aMT6s rhythms between PER3 5 /PER3 5 and PER3 4 /PER3 4 subjects at baseline. After light administration, PER3 4 /PER3 4 subjects advanced their aMT6s acrophase (p < 0.05), and showed a trend of advanced sleep-wake timing. In conclusion, significant associations were observed between PER3 polymorphic variants/their combinations and both diurnal preference and the response to light.

  15. La strada e il suo doppio. Le vetrine di Albe Steiner per La Rinascente a Milano

    Directory of Open Access Journals (Sweden)

    Cristina Casero

    2011-01-01

    Full Text Available Una analisi delle vetrine progettate da Albe Steiner per la Rinascente di Milano nella prima metà degli anni Cinquanta basata sui materiali dell'archivio Albe e Lica Steiner conservato presso il Politecnico di Milano.

  16. A Methodology for Determining the Marginal Cost Per Student at the Naval Postgraduate School

    National Research Council Canada - National Science Library

    Eckardt, John

    1997-01-01

    The overall objective of this thesis was to develop a flexible model to determine the marginal cost of graduate education per student for each of the various curricula at the Naval Postgraduate School (NPS...

  17. Links between cardiovascular disease and osteoporosis in postmenopausal women: serum lipids or atherosclerosis per se?

    DEFF Research Database (Denmark)

    Bagger, Y Z; Rasmussen, Henrik Berg; Alexandersen, P

    2007-01-01

    Epidemiological observations suggest links between osteoporosis and risk of acute cardiovascular events and vice versa. Whether the two clinical conditions are linked by common pathogenic factors or atherosclerosis per se remains incompletely understood. We investigated whether serum lipids...

  18. CALiPER Summary of Results. Round 13 of Product Testing

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2011-10-01

    The Department of Energy (DOE) Commercially Available Light-Emitting Diode (LED) Product Evaluation and Reporting (CALiPER) Program has been purchasing and testing general illumination solid-state lighting (SSL) products since 2006.

  19. Il nuovo server per il calcolo parallelo al CILEA: HP 9000 Enterprise Server K580

    OpenAIRE

    Bonini, Francesca

    1999-01-01

    In questo articolo è presentato il nuovo server ad alte prestazioni, per il calcolo parallelo, disponibile al Cilea. In particolare, viene fornita una breve descrizione dei pacchetti software disponibili, della configurazione e delle modalità di utilizzo della macchina.

  20. Primer registro de Florometra magellanica (Bell, 1882 (Echinodermata: Crinoidea para el Perú

    Directory of Open Access Journals (Sweden)

    Elba Prieto Rios

    2011-08-01

    Full Text Available Se registra por primera vez para el Perú al Crinoideo (Echinodermata Florometra magellanica (Bell, 1882. La especie fue recolectada en el talud continental (360 – 814 m frente al departamento de Piura al norte del Perú (3°38,67’S, 81° 2,73’W. El material de referencia se encuentra depositado en la Colección Científica del Instituto del mar del Perú (IMARPE, Lima, Perú y en la Colección Nacional de Equinodermos de la Universidad Nacional Autónoma de México, Ciudad de México.

  1. Intervista con Sergio Bertolucci, Direttore per la Ricerca e le Tecnologie d'Informazione

    CERN Multimedia

    CERN Video Productions

    2009-01-01

    Domande : 1. Come ci si sente come Direttore per la Ricerca al CERN in unmomento in cui LHC è pronto a partire con i dati per la prima volta? 2. Cosa si può aspettare la comunità internazionale dei fisici che utilizzeranno LHC dall'ernergia iniziale di 3,5 TeV per fascio? 3. Quale scoperta desidererebbe fare lei, come fisico, in questa prima fase? 4. Il FERMILAB può ancora competere con LHC all'energia di 3,5 TeV per fascio? 5. Quanto è difficile far funzionare LHC e quanto è complessa la presa dati? 6. Qual'è l'importanza storica di LHC nel contesto della ricerca scientifica? 7. Quali ricadute sulla società possiamo aspettarci da LHC?

  2. 16 CFR 308.5 - Pay-per-call service standards.

    Science.gov (United States)

    2010-01-01

    ... required if the provider of pay-per-call services offers the caller an affirmative means (such as pressing..., content, language, featured personality, characters, tone, message, or the like. (i) Prohibition...

  3. IMPACT OF INFLATION ON PER CAPITA INCOME IN EMERGING ECONOMIES: EVIDENCE FROM BRICS NATIONS

    Directory of Open Access Journals (Sweden)

    Khalid Ashraf CHISTI

    2015-12-01

    Full Text Available In this paper an attempt has been made to analyse the impact of Inflation on per capita income of emerging economies. In order to achieve the objective of the study the researchers have taken five major emerging countries of the world which are the members of BRICS. For the purpose of analysis, the data of thirteen years has been taken from 1999 to 2011. After employing the regression model, the results confirm that independent variable (inflation does not statistically influence the dependent variable (Per Capita Income in three countries which are India, Brazil and South Africa. However, in the other two countries (China and Russia the findings affirm the independent variable (Inflation does statistically influence the dependent variable (Per Capita Income.Therefore, it can be concluded that a change in the inflation rate can not necessarily bring a change in the per capita income of a country.

  4. Discorso globale e contesti locali. Quale futuro per il programma di riforma agraria in Ruanda?

    Directory of Open Access Journals (Sweden)

    Johan Pottier

    2013-07-01

    Full Text Available La maggior parte degli sforzi per trasformare l’economia sub-sahariana negli anni Ottanta e Novanta faceva seguito ai cosiddetti “accordi di Washington”; questi sforzi avevano l’obiettivo di ridimensionare il ruolo dello Stato e liberalizzare i prezzi agricoli. La strategia prescritta funzionò per alcuni, ma non per la maggioranza dei produttori agricoli; all’inizio del XXI secolo è necessario, ancora una volta, un “momento di ripensamento”. I responsabili delle politiche agricole suggeriscono ora che,per indurre un cambiamento efficace, il nuovo modo di pensare deve fare i conti con modelli inappropriati di coltivazione, cogliere le dimensioni sociali e politiche dei cambiamenti indotti dalle moderne tecniche di coltivazione e venire a patti con i locali modi di comprensione dei contesti complessi (Scoones, Devereux, Haddad 2005, p. 3.

  5. TeliaSonera jääb pakutud hinna juurde / Per-Arne Blomquist

    Index Scriptorium Estoniae

    Blomquist, Per-Arne

    2009-01-01

    TeliaSonera grupi finantsdirektor Per-Arne Blomquist vastab küsimustele, mis puudutavad Eesti Telekomi aktsiatele ostupakkumise tegemist ning võimalikke muudatusi ettevõttes pärast Eesti Telekomi aktsiate omandamist

  6. Researchers develop CCD image sensor with 20ns per row parallel readout time

    CERN Multimedia

    Bush, S

    2004-01-01

    "Scientists at the Rutherford Appleton Laboratory (RAL) in Oxfordshire have developed what they claim is the fastest CCD (charge-coupled device) image sensor, with a readout time which is 20ns per row" (1/2 page)

  7. Ni rara, ni extraordinaria: política y corporalidad en Eva Perón

    National Research Council Canada - National Science Library

    Karina Elizabeth Vázquez

    2017-01-01

    This essay analyzes images and representations of Eva Perón combining theories of corporeality and affection with theories of the photo-image proposed by WJT Mitchell, Roland Barthes and Susan Sontag...

  8. The analysis of deregulated expression and methylation of the PER2 genes in gliomas.

    Science.gov (United States)

    Fan, Wang; Chen, Xiaowei; Li, Caiyan; Chen, Lvan; Liu, Pingfei; Chen, Zhijun

    2014-01-01

    Growing evidence shows that disruption of circadian rhythm may be a risk factor in the development of glioma. However, the molecular mechanisms of genes controlling circadian rhythm in glioma cells have not been explored and differential expression of the circadian clock genes in glioma and non-tumor cells may provide a molecular basis for manifesting this mechanism. The aim of the following study is to analyze the PER2 expression involved in the pathogenesis of glioma. Using immunohistochemical staining, methylation specific polymerase chain reaction techniques, we examined the expression of the most important clock genes, PER2, in 92 gliomas. The association between tumor grade (high-grade/low-grade gliomas) and expression of the investigated proteins (negative/positive) was assessed using the Spearman, Chi-square test and two-sample t-test, included in the Statistical Package for the Social Science, version 13.0. Using Spearman Correlation to analyse correlation between the expression of PER 2 and PER2 promoter methylation. Our results reveal disturbances in the expression of the period 2 (PER2) genes in most (52.17%) of the glimoa cells in comparison with the nearby non-cancerous cells and the PER2 gene deregulation is most probably by methylation of the PER2 promoter. Since, the circadian clock controls expression of cell-cycle related genes, we suggest that disturbances in PER2 gene expression may result in disruption of the control of the normal circadian clock, thus benefiting the survival of cancer cells and promoting carcinogenesis. Differential expression of circadian genes in non-cancerous and cancerous cells may provide a molecular basis for chronotherapy of glioma.

  9. Preliminary results of V440 Per and α UMi observations with the Poznan Spectroscopic Telescope

    Science.gov (United States)

    Fagas, M.; Baranowski, R.; Bartczak, P.; Borczyk, W.; Dimitrow, W.; Kaminski, K.; Kwiatkowski, T.; Ratajczak, R.; Rozek, A.; Schwarzenberg-Czerny, A.

    2009-03-01

    Presented herein are preliminary radial velocity results for two classical Cepheids: V440 Per and α UMi (Polaris). Both stars have been observed with the Poznan Spectroscopic Telescope (PST), operational since Aug 2007 at the Borowiec Station of Poznań Astronomical Observatory in Poland. Data obtained for V440 Per suggest the presence of a low-amplitude secondary mode of pulsations. Results of α UMi observations confirm further pulsation amplitude growth, as observed during the last decades.

  10. Lifetime and per year productivity of sows in four pig farms in the tropics of Mexico.

    Science.gov (United States)

    Ek-Mex, Jesús Enrique; Segura-Correa, José Candelario; Alzina-López, Alejandro; Batista-Garcia, Laura

    2015-03-01

    The objectives of this study were to estimate the lifetime and per year productivity of sows and to determine the effect of some factor on those traits in four pig farms in the tropics of Mexico. Data from 7526 sows for lifetime number of piglets born alive per sow (LBA), lifetime kilograms of piglets at farrowing (LKF), number of piglets born alive per year (NPF/Y), and kilograms of piglets at farrowing per year (KPF/Y); and data from 7230 sows for lifetime number of piglets weaned (LPW), lifetime kilograms of piglets weaned (LKW), number of piglets weaned per year (NPW/Y), and kilograms of piglets weaned per year (KPW/Y) per sow were used. The statistical model for all traits included the fixed effects of farm, year of first farrowing, season of first farrowing, litter size at first farrowing, age at first farrowing, removal reason, simple interactions, and the error term. The means for LBA, LKF, NPF/Y, and KPF/Y were 45.1 piglets, 67.1 kg, 22.7 piglets, and 33.7 kg, respectively. The means for LPW, LKW, NPW/Y, and KPW/Y were 43.2 piglets, 251.9 kg, 21.5 piglets, and 125.1 kg, respectively. All factors were significant for all traits, except for age at first farrowing on LPW and LKW. Sows with large litter sizes and those that farrowed the first time, at an early age, had the highest lifetime and per year productivity. Therefore, more care and better management should be provided to those types of sows to improve the farms profit.

  11. Distribution Dynamics of Regional GDP per Employee in Unifi ed Germany

    OpenAIRE

    Vollmer, Sebastian; Holzmann, Hajo; Ketterer, Florian; Klasen, Stephan

    2010-01-01

    We investigate to what extent convergence in production levels per worker has been achieved in Germany since unification. To this end, we model the distribution of GDP per employee across German districts using two-component normal mixtures. While in the first year after unification, the two component distributions were clearly separated and bimodal, corresponding to the East and West German districts, respectively, in the following years they started to merge showing only one mode. Still, us...

  12. Acerca del nombre del Perú en la actual Colombia

    Directory of Open Access Journals (Sweden)

    Juan Friede

    1962-03-01

    Full Text Available Como es sabido, la adaptación del nombre "Perú" al Imperio Incaico es de origen netamente español. Los indios del Perú no llamaban así a su territorio, como lo confirman Valera, Cieza de León, Montesinos, Garcilaso y otros. Tenían nombres para designar las distintas provincias pero no para la totalidad del imperio de los incas.

  13. presenze dell'esotico nella poesia per l'infanzia di toti scialoja

    African Journals Online (AJOL)

    User

    e lo spazio: «il bambino è condizionato da una favolosa percezione dello spazio e del tempo. Essi risultano per lui infiniti ed eterni». (Scialoja, 1991a:179). La distanza nel tempo si manifesta per lo più nei riferimenti alla storia o al mito greci, che possono collidere con la contemporaneità (come nel caso di Micene / cinema, ...

  14. Charge collection efficiency in ionization chambers exposed to electron beams with high dose per pulse.

    Science.gov (United States)

    Laitano, R F; Guerra, A S; Pimpinella, M; Caporali, C; Petrucci, A

    2006-12-21

    The correction for charge recombination was determined for different plane-parallel ionization chambers exposed to clinical electron beams with low and high dose per pulse, respectively. The electron energy was nearly the same (about 7 and 9 MeV) for any of the beams used. Boag's two-voltage analysis (TVA) was used to determine the correction for ion losses, k(s), relevant to each chamber considered. The presence of free electrons in the air of the chamber cavity was accounted for in determining k(s) by TVA. The determination of k(s) was made on the basis of the models for ion recombination proposed in past years by Boag, Hochhäuser and Balk to account for the presence of free electrons. The absorbed dose measurements in both low-dose-per-pulse (less than 0.3 mGy per pulse) and high-dose-per-pulse (20-120 mGy per pulse range) electron beams were compared with ferrous sulphate chemical dosimetry, a method independent of the dose per pulse. The results of the comparison support the conclusion that one of the models is more adequate to correct for ion recombination, even in high-dose-per-pulse conditions, provided that the fraction of free electrons is properly assessed. In this respect the drift velocity and the time constant for attachment of electrons in the air of the chamber cavity are rather critical parameters because of their dependence on chamber dimensions and operational conditions. Finally, a determination of the factor k(s) was also made by zero extrapolation of the 1/Q versus 1/V saturation curves, leading to the conclusion that this method does not provide consistent results in high-dose-per-pulse beams.

  15. P. Ortoleva, Dal sesso al gioco. Un’ossessione per il XXI° secolo?

    Directory of Open Access Journals (Sweden)

    Mauro Salvador

    2013-03-01

    Full Text Available In questo pamphlet edito da Espress per la collana “Tazzine di caffé con panna” Ortoleva riprende le fila del discorso avviato ne Il secolo dei media (2008. L’autore riparte dalla liberazione sessuale e dalla diffusione della pornografia della seconda metà del Novecento per giungere a parlare del contemporaneo processo di “ludicizzazione del reale”

  16. Primer Registro para el Perú de Brachycaudus schwartzi (Bórner (Hemiptera: Aphididae

    Directory of Open Access Journals (Sweden)

    Walter Díaz

    2013-04-01

    Full Text Available Se registra por primera vez para el Perú la especie Brachycaudus schwartzi (Bórner (Hemiptera: Aphididae, “pulgón pardo del duraznero”. La especie ha sido colectada en el departamento de Tacna. Material de referencia se encuentra depositado en la Colección Referencial de Insectos de la Unidad del Centro de Diagnóstico de Sanidad Vegetal del SENASA, Lima, Perú.

  17. Kompetenz, Persönlichkeit und Berufserfolg in Zeiten organisationalen Wandels

    OpenAIRE

    Klimesch, Susanne

    2014-01-01

    Die vorliegende Studie untersuchte den Zusammenhang zwischen Kompetenz, Persönlichkeit und Berufserfolg. Für die Erfassung der beruflichen Kompetenz wurde ein neu entwickeltes Verfahren, das Inventar zur Erfassung beruflicher Kompetenz "I-BeKo" mit fünf basalen Kompetenzkategorien zur Anwendung gebracht. Persönlichkeit wurde über den eigenschaftstheoretischen Ansatz beschrieben und auf das Fünf-Faktoren-Modell (Big-5) Bezug genommen. Berufserfolg (career success) wurde über objektive (Einkomm...

  18. Sistema de control per a la producció microbiana de proteïnes

    OpenAIRE

    Pinsach, Jaume; Mas i Rocabayera, Carles de; López Santín, Josep

    2006-01-01

    El Departament d'Enginyeria Química de la UAB treballa en el desenvolupament de noves tecnologies per millorar, tant qualitativament com quantitativa, la producció de proteïnes recombinants -obtingudes mitjançant modificació genètica d'un organisme-. Ara acaba de presentar un sistema de control per automatitzar tot el procés.

  19. Nuevos bivalvos para el Perú en Bahía Independencia

    OpenAIRE

    Cornejo, Oswaldo; Laboratorio de Ecología, Facultad de Ciencias Biológicas. Universidad Nacional Mayor de San Marcos; Paredes, Carlos; Laboratorio de Biología y Sistemática de Invertebrados Marinos, Facultad de Ciencias Biológicas. Universidad Nacional Mayor de San Marcos

    2013-01-01

    The following species of marine bivalves have been recorded for the first time in Peru Nucula (Nucula) pisum Sowerby I,1833 and Lyonsia delicata Marincovich,1973, colected in Independencia Bay in Pisco, Peru, at 2002. Se registran por primera vez para el Perú las siguientes especies de bivalvos Nucula (Nucula) pisum Sowerby I, 1833, y Lyonsia delicata Marincovich, 1973, colectadas en Bahía Independencia, Pisco, Perú, en el 2002.

  20. Vegetable cost metrics show that potatoes and beans provide most nutrients per penny.

    Directory of Open Access Journals (Sweden)

    Adam Drewnowski

    Full Text Available Vegetables are important sources of dietary fiber, vitamins and minerals in the diets of children. The United States Department of Agriculture (USDA National School Lunch Program has new requirements for weekly servings of vegetable subgroups as well as beans and peas. This study estimated the cost impact of meeting the USDA requirements using 2008 national prices for 98 vegetables, fresh, frozen, and canned. Food costs were calculated per 100 grams, per 100 calories, and per edible cup. Rank 6 score, a nutrient density measure was based on six nutrients: dietary fiber; potassium; magnesium; and vitamins A, C, and K. Individual nutrient costs were measured as the monetary cost of 10% daily value of each nutrient per cup equivalent. ANOVAs with post hoc tests showed that beans and starchy vegetables, including white potatoes, were cheaper per 100 calories than were dark-green and deep-yellow vegetables. Fresh, frozen, and canned vegetables had similar nutrient profiles and provided comparable nutritional value. However, less than half (n = 46 of the 98 vegetables listed by the USDA were were consumed >5 times by children and adolescents in the 2003-4 National Health and Nutrition Examination Survey database. For the more frequently consumed vegetables, potatoes and beans were the lowest-cost sources of potassium and fiber. These new metrics of affordable nutrition can help food service and health professionals identify those vegetable subgroups in the school lunch that provide the best nutritional value per penny.

  1. Sviluppo di un nuovo trigger con identificazione di quark-b per il canale Z($\

    CERN Document Server

    Donato, Silvio

    La ricerca del decadimento del bosone di Higgs H -> b b è uno dei canali più importanti per verificare se la particella di massa 125 GeV circa, recentemente scoperto da ATLAS e CMS, corrisponde effettivamente al bosone di Higgs previsto dal Modello Standard. Questo decadimento, insieme a H -> tau tau, è fondamentale per misurare l'accoppiamento del bosone con i fermioni. Il fondo di QCD rende poco sensibile l'osservazione di questo decadimento nella produzione diretta del bosone di Higgs. Per questo motivo il decadimento H -> b b viene ricercato quando l'Higgs è prodotto in associazione con i bosoni vettore W/Z, attraverso il cosiddetto processo di ``Higgs-strahlung''. Il decadimento leptonico dei bosoni vettore ad alto pT permette di ridurre il fondo di QCD e di realizzare trigger per osservare il canale. In questa tesi è stato realizzato un trigger per osservare il canale H + Z -> b b + nu nu nella regione a bassa EtMiss (fino a 80 GeV) con l'esperimento CMS. Per avere il trigger con un rate accettabi...

  2. Food-anticipatory activity and liver per1-luc activity in diabetic transgenic rats

    Science.gov (United States)

    Davidson, Alec J.; Stokkan, Karl-Arne; Yamazaki, Shin; Menaker, Michael

    2002-01-01

    The mammalian Per1 gene is an important component of the core cellular clock mechanism responsible for circadian rhythms. The rodent liver and other tissues rhythmically express Per1 in vitro but typically damp out within a few cycles. In the liver, the peak of this rhythm occurs in the late subjective night in an ad lib-fed rat, but will show a large phase advance in response to restricted availability of food during the day. The relationship between this shift in the liver clock and food-anticipatory activity (FAA), the circadian behavior entrained by daily feeding, is currently unknown. Insulin is released during feeding in mammals and could serve as an entraining signal to the liver. To test the role of insulin in the shift in liver Per1 expression and the generation of FAA, per-luciferase transgenic rats were made diabetic with a single injection of streptozotocine. Following 1 week of restricted feeding and locomotor activity monitoring, liver was collected for per-luc recording. In two separate experiments, FAA emerged and liver Per1 phase-shifted in response to daytime 8-h food restriction. The results rule out insulin as a necessary component of this system.

  3. Genetic Association of the PERIOD3 (Per3) Clock Gene with Bipolar Disorder.

    Science.gov (United States)

    Brasil Rocha, Paulo Marcos; Campos, Simone Becho; Neves, Fernando Silva; da Silva Filho, Humberto Corrêa

    2017-09-01

    Circadian rhythms have been linked to psychiatric disorders such as Depression and Bipolar Disorder (BD). Given previous evidences of sleep/circadian disturbances as well as the genetic susceptibility for BD, we decided to investigate the possible link between the PERIOD3 (Per3) circadian gene and BD. This is a genetic association case (BD) vs. control study of the Per3 gene. We further subdivided our BD sample into "good sleepers" (PSQI ≤5) and "poor sleepers" (PSQI>5) according to the Pittsburgh Sleep Quality Index (PSQI) global score, and then we assessed genetic association of the Per3 gene with sleep quality in the BD group. There were 209 cases and 213 controls in our sample. The GT genotype of the SNP rs707467 significantly associated with BD (χ2=8.80; p-value=0.01; adjusted residual=±2.6). We also found significant association of the SNP rs10462020 allele T with BD (χ2=5.81; p-value=0.01) as well as the genotype TT (χ2= 6.01; p-value=0.04; adjusted residual=±2.4). In this study we demonstrated evidences of genetic association between the Per3 gene and BD. The results of association between the Per3 gene and BD in our sample may bring additional evidence to the former findings of association between the Per3 gene and BD.

  4. Anaerobic digestion of industrial hemp-effect of harvest time on methane energy yield per hectare

    Energy Technology Data Exchange (ETDEWEB)

    Kreuger, E.; Escobar, F.; Bjoernsson, L. [Department of Biotechnology, Lund University, P.O. Box 124, SE-221 00 Lund (Sweden); Prade, T.; Svensson, S.-E.; Englund, J.-E. [Department of Agriculture-Farming Systems, Technology and Product Quality, Swedish University of Agricultural Sciences, P.O. Box 104, SE-230 53 Alnarp (Sweden)

    2011-02-15

    There is a worldwide emphasis to increase the share of renewable transportation fuels. When using agricultural land for production of renewable transportation fuels, the energy output per hectare for different crops and transportation fuels is a crucial factor. In this study, the gross methane energy yield per hectare from anaerobic digestion of industrial hemp (Cannabis sativa L.), was determined at four different harvest times between July and October in Southern Sweden, a cold climate region. The biomass yield was determined for three years and the methane yield was determined for two years through the biochemical methane potential test. The highest biomass yield, 16 tonnes dry matter per hectare on an average, and the highest methane energy yield per hectare was achieved when the hemp was harvested in September or October, with an average gross methane energy yield of 136 {+-} 24 GJ per hectare. There was no significant difference in the specific methane yield between the harvest times; the average being 234 {+-} 35 m{sup 3} per tonne volatile solids. Biogas from hemp turned out to be a high yielding alternative to the currently dominating renewable transportation fuels produced from crops grown in Sweden: ethanol from wheat and biodiesel from rapeseed. (author)

  5. Role of type II protein arginine methyltransferase 5 in the regulation of Circadian Per1 gene.

    Directory of Open Access Journals (Sweden)

    Jungtae Na

    Full Text Available Circadian clocks are the endogenous oscillators that regulate rhythmic physiological and behavioral changes to correspond to daily light-dark cycles. Molecular dissections have revealed that transcriptional feedback loops of the circadian clock genes drive the molecular oscillation, in which PER/CRY complexes inhibit the transcriptional activity of the CLOCK/BMAL1 heterodimer to constitute a negative feedback loop. In this study, we identified the type II protein arginine methyltransferase 5 (PRMT5 as an interacting molecule of CRY1. Although the Prmt5 gene was constitutively expressed, increased interaction of PRMT5 with CRY1 was observed when the Per1 gene was repressed both in synchronized mouse liver and NIH3T3 cells. Moreover, rhythmic recruitment of PRMT5 and CRY1 to the Per1 gene promoter was found to be associated with an increased level of histone H4R3 dimethylation and Per1 gene repression. Consistently, decreased histone H4R3 dimethylation and altered rhythmic Per1 gene expression were observed in Prmt5-depleted cells. Taken together, these findings provide an insight into the link between histone arginine methylation by PRMT5 and transcriptional regulation of the circadian Per1 gene.

  6. Spatial data modeling in disposable income per capita in china using nationwide spatial autoregressive (SAR

    Directory of Open Access Journals (Sweden)

    Tuti Purwaningsih

    2017-07-01

    Full Text Available China as a country became the economic center of the world. However, with a population of 1.3 billion, China's per capita income is still at number 80 in the world. In the world, considering the imbalance between town and country with 100 million people still living in poverty. Thus, to address this imbalance, it is necessary to study the condition in depth, because income per capita is often used as a benchmark to measure the prosperity of a country. With greater and equitable income per capita, the country will be judged increasingly affluent. Two factors, mainly industry and tourism, play an important role in the economic progress in China. These are include Per capita Disposable Income Nationwide (yuan, Total Value of Exports of operating units (1,000 USD, Registered Unemployed Person in Urban Area (10000 person, Foreign Exchange Earning from International tourism(in millions USD and Number of Overseas Visitor Arrivals (million person/time. Thus, it is necessary to investigate the influence of these factors to increase per capita income. Since the economic development of a region usually affect the surrounding area, this study aims to include spatial effects, using Spatial Autoregressive (SAR Model. The results suggest that the per capita income affected by the Tourism factor is about 58.65% (R-squared.

  7. Velocity, stroke rate, and distance per stroke during elite swimming competition.

    Science.gov (United States)

    Craig, A B; Skehan, P L; Pawelczyk, J A; Boomer, W L

    1985-12-01

    The mean velocity of 9 out of 10 women's events during the U.S. Olympic Swimming Trials was greater in 1984 as compared to 1976. Three of the 10 men's events showed improvement. In 9 out of these 12 events, the increased velocity was accounted for by increased distance per stroke (range, -3 to -13%). In the women's 100-m butterfly and 100-m backstroke, increased velocity was due solely to faster stroke rates. The finalists in each event were compared to those whose velocities were 3-7% slower. In almost all events and stroke styles, the finalists achieved greater distances per stroke than did the slower group. In the men's events increased distance per stroke was associated with decreased stroke rate, except in the backstroke, in which both were increased for the finalists. Although the faster women swimmers generally had greater distances per stroke, they were more dependent than men on faster stroke rates to achieve superiority. The profile of velocity for races of 200 m and longer indicated that as fatigue developed the distance per stroke decreased. The faster swimmers compensated for this change by maintaining or increasing stroke rate more than did their slower competitors. This study indicates that improvements and superiority in stroke mechanics are reflected in the stroke rate and distance per stroke used to swim a race.

  8. Valutazione dell'affidabilità degli operatori per l'identificazione microscopica di peli di mammiferi

    Directory of Open Access Journals (Sweden)

    Paolo Ciucci

    2003-10-01

    Full Text Available La quantificazione dei resti indigesti contenuti negli escrementi è tra le tecniche più frequentemente utilizzate per studiare la dieta del lupo, dove il riconoscimento delle specie preda, nel caso dei mammiferi, si basa su caratteristiche microscopiche distintive del pelo. Tale tecnica, è tuttavia soggetta ad errori individuali nonostante l'esperienza dell'operatore e il ricorso a testi o collezioni di riferimento. Congiuntamente ad una mancata standardizzazione delle procedure di preparazione e trattamento del campione, queste fonti di errore possono alterare significativamente i risultati. Nell'ambito di un progetto UE-Life sull'ecologia del Lupo, in tre Parchi Regionali dell'Emilia-Romagna (2001-2004, abbiamo quindi applicato una procedura standardizzata per la selezione, raccolta, preparazione e trattamento dei campioni fecali di lupo ai fini dell'analisi della dieta. A tal fine è stato organizzato un corso di formazione da parte di docenti qualificati per un totale di 150 ore, suddiviso in moduli e articolato in esercitazioni e prove pratiche di autovalutazione. Al corso, e dopo un ulteriore periodo di esercitazioni individuali (ca. 300 ore/operatore, è quindi seguito un esame di identificazione che ha permesso di quantificare l'affidabilità di ciascun operatore. Il test per l'identificazione a livello di specie è stato basato su un campione di 120 peli, la cui specie di origine era ignota ai candidati (blind test, suddivisi tra ungulati selvatici (n=54: Capriolo, Cervo, Daino, Muflone, Cinghiale, ungulati domestici (n=21: bovini, ovini, caprini, equini, canidi (n= 18: lupo, cane, volpe e altre specie (n=27: lepre, marmotta, tasso, martora, faina, puzzola, gatto, scoiattolo, talpa, muridi. Un sottocampione di 65 peli è stato utilizzato per valutare l'affidabilità nel riconoscimento delle classi d'età (< 5 mesi, ≥ 5 mesi per le sole categorie degli ungulati selvatici (n=54 e degli

  9. Costo anual per cápita en primer nivel de atención por género Cost per capita in outpatients by gender

    Directory of Open Access Journals (Sweden)

    Enrique Villarreal-Ríos

    2011-03-01

    Full Text Available El objetivo de este artículo es estimar el costo per cápita anual por género en primer nivel de atención. MÉTODOS: estudio de costo realizado en Unidades de Medicina Familiar en México. La información correspondió al año 2004 y el estudio se dividió en perfil de uso y costo de la atención. PERFIL DE USO DE LO SERVICIOS: se estudiaron los registros clínicos de 1,585 pacientes adscritos a unidades de medicina familiar. El perfil de uso se definió mediante el promedio y los motivos de atención por departamento, género y grupo de edad. COSTO DE LA ATENCIÓN: estimado en dólares estadounidenses incluyó costo unitario fijo (departamentalización ajustada por productividad, el costo unitario variable (técnica de microcosteo, costo unitario por departamento y motivo de atención, y costo unitario por departamento, quinquenio y género. La esperanza de vida fue de 73 años para los hombres y 78 para las mujeres. Se identificaron tres escenarios. RESULTADOS: el costo anual per capita es superior en la mujer US $73.24 (IC 95% $11.38 - $197.49 que en el hombre $ 53.11 (IC 95% 2.51 - 207.71. CONCLUSIÓN: en primer nivel de atención el costo per cápita en las mujeres es mayor que en los hombres, información valiosa en el proceso de planeación de los servicios de salud.The objective of this study is to identify the annual cost per capita by gender in first level of attention. It is a cost study in Family Physician Units in Mexico. The information corresponded to the year of 2004 and the study divided in the use profile and cost attention. USE PROFILE OF SERVICES: it was studied 1,585 clinical registries of patients, use profile defined by average and attention reasons by department, gender and age group. COST ATTENTION: considered in American dollars it included fixed unit cost (departmentalization adjusted by productivity, variable unit cost (micro cost technical, department unite cost by type attention, and department unit cost by age

  10. SU-E-T-296: Single Field Per Day Vs. Multiple Fields Per Day and the Impact On BED in Proton Therapy Treatment

    Energy Technology Data Exchange (ETDEWEB)

    Grantham, K [University of Missouri-Columbia, St. Louis, MO (United States); Wooten, H [Washington University School of Medicine, St Louis, MO (United States); Zhao, T [Washington University School of Medicine, St. Louis, MO (United States); Klein, E [Washington University, Saint Louis, MO (United States)

    2014-06-01

    Purpose: A common practice, in proton therapy, is to deliver a rotating subset of fields from the treatment plan for the daily fractions. This study compares the impact this practice has on the biological effective dose (BED) versus delivering all planned fields daily. Methods: For two scenarios (a phantom with a geometry approximating the anatomy of a prostate treatment with opposing lateral beams, and a clinical 3-field brain treatment), treatment plans were produced in Eclipse (Varian) to simulate delivery of one, two, and three fields per fraction. The RT-Dose file, structure set, and α/β ratios were processed using in-house MATLAB code to return a new RT-Dose file containing the BED (including a proton RBE of 1.1) which was imported back into Eclipse for analysis. Results: For targets and regions of field overlap in the treatment plan, BED is not affected by delivery regimen. In the phantom, BED in the femoral heads showed increased by 20% when a single field was used rather than two fields. In the brain treatment, the minimum BED to the left optic nerve and the pituitary gland increased by 13% and 10% respectively, for a one-field regime compared to three-fields per fraction. Comparing the two-field and threefield regimes, the optic nerve BED was not significantly affected and the minimum pituitary BED was 4% higher for two fields per day. Conclusion: Hypo-fractionation effects, in regions of non-overlap of fields, significantly increase the BED to the involved tissues by as much as 20%. Care should be taken to avoid inadvertently sacrificing plan effectiveness in the interest of reduced treatment time.

  11. Narrowband ultraviolet B three times per week is more effective in treating vitamin D deficiency than 1600 IU oral vitamin D₃ per day: a randomized clinical trial.

    Science.gov (United States)

    Bogh, M K B; Gullstrand, J; Svensson, A; Ljunggren, B; Dorkhan, M

    2012-09-01

    It is known that narrowband ultraviolet B (NB-UVB) radiation and oral vitamin D(3) supplementation can both improve serum levels of vitamin D, expressed as 25-hydroxyvitamin D(3) [25(OH)D(3) ]. However, surprisingly few studies have compared the effects of the two interventions in treating vitamin D deficiency. To compare the effect of NB-UVB exposure with oral vitamin D(3) supplementation on vitamin D levels in patients with vitamin D deficiency. Seventy-three participants with vitamin D deficiency [25(OH)D(3) ≤ 25 nmol L(-1) ] were consecutively enrolled from February 2010 to May 2011, avoiding the summer period (June to September). The participants were randomized into two groups, one receiving full body NB-UVB exposure three times per week, the other receiving 1600 IU (40 μg) oral vitamin D(3) per day together with 1,000 mg calcium. Thirty-two participants completed the 6-week study period, 16 in each group. In both groups blood samples were obtained at baseline and after 3 and 6 weeks. We found a significantly greater increase in 25(OH)D(3) levels (mean) in the NB-UVB treated group (from 19·2 to 75 nmol L(-1) ) compared with the oral vitamin D(3) treated group (from 23·3 to 60·6 nmol L(-1) ) after 6 weeks of treatment (P = 0·02), accompanied by a significant decrease in parathyroid hormone for the whole group (from 5·3 to 4·2 pmol L(-1) , P = 0·028). Full body NB-UVB three times per week is more effective in treating vitamin D deficiency than prescription of a daily oral intake of 1600 IU (40 μg) vitamin D(3) . © 2012 The Authors. BJD © 2012 British Association of Dermatologists.

  12. Environmental analysis applied to schools. Methodologies for data acquisition; Analisi ambientale iniziale per gli istituti d'istruzione. Metodologia per l'acquisizione dei dati

    Energy Technology Data Exchange (ETDEWEB)

    Andriola, L.; Ceccacci, R. [ENEA, Div. Caratterizzazione dell' Ambiente e del Territorio, Centro Ricerche Casaccia, Rome (Italy)

    2001-07-01

    The environment analysis is the basis of environmental management for organizations and it is considered as the first step in EMAS. It allows to identify, deal with the issues and have a clear knowledge on environmental performances of organizations. Schools can be included in the organizations. Nevertheless, the complexity of environmental issues and applicable regulations makes very difficult for a school, that wants to implement an environmental management system (EMAS, ISO 14001, etc.), to face this first step. So, it has been defined an instrument, that is easy but complete and coherent with reference standard, to let schools choose their process for elaborating the initial environmental revue. This instrument consists, essentially, in cards that, if completed, facilitate the drafting of the environmental analysis report. [Italian] L'analisi ambientale iniziale costituisce il presupposto di qualsiasi azione di gestione ambientale da parte di un'organizzazione ed e' esplicitamente prevista, come prima tappa, in EMAS. Essa consente infatti di individuare ed approfondire le problematiche ambientali e di fotografare, per mezzo di riferimenti oggettivi, le prestazioni ambientali di un'organizzazione, e quindi anche di una scuola, in modo da poter stabilire e controllare nel tempo gli obiettivi di miglioramento. Tuttavia la complessita' delle problematiche ambientali e delle relative normative di riferimento rende estremamente difficoltoso, per un istituto scolastico che intenda intraprendere un percorso di gestione ambientale comunque finalizzato (EMAS, ISO 14001, Comunicazione ambientale, ecc.) compiere questo passo iniziale. E' stato pertanto realizzato uno strumento semplificato, ma comunque completo e coerente con gli standard di riferimento, per consentire alle scuole di effettuare il percorso di elaborazione di un'analisi ambientale iniziale. Lo strumento consiste essenzialmente in schede che, una volta compilate

  13. "Cantar per moldre, cantar per no plorar": L'expressió del patiment femení en l'entorn rural Senufo

    OpenAIRE

    Lorillard, Marie

    2012-01-01

    A les zones rurals senufo de l’Àfrica occidental, les tradicions orals tenen una gran importància en la vida quotidiana. Al voltant de la pedra de molí, a l’ombra dels murs de la seva concessió, les dones comencen a cantar, mentre molen els cereals. Aquesta és una oportunitat perfecta perquè expressin les seves emocions reprimides, per posar en paraules les penes de la pobresa, la desgràcia, les dificultats de la vida domèstica o fins i tot els dolors de dol. Aquest article examina de prop aq...

  14. La democracia y las organizaciones de derechos humanos en el Perú : La Coordinadora Nacional de Derechos Humanos en el período 1997-2001

    OpenAIRE

    Alayza Mujica, Ernesto

    2010-01-01

    Pareció importante y motivador estudiar los documentos y analizar la actuación de la Coordinadora Nacional de Derechos Humanos, en el proceso de cierre del período del régimen de Alberto Fujimori, llamado de transición a la democracia, correspondiente a 1997-2001. En una situación de monopolio o copamiento de instituciones, en que se guardaron formalidades para aparentar la continuación de un régimen democrático, las organizaciones de derechos humanos integradas en una Coordinadora Naciona...

  15. Implementación de un sistema de buen gobierno corporativo en el sector minero del Perú – Caso Southern Perú

    OpenAIRE

    López Abad, Rafael Fernando

    2010-01-01

    Actualmente debido a la crisis de la economía mundial, y a la falta de confianza en mercados corporativos, los grandes inversores buscan alternativas más rentables y seguras. Estos hechos han originado que los temas relacionados con el Gobierno Corporativo y Desarrollo Sostenible sean cada vez más importante en las agendas de sociedades y los organismos regulatorios, a fin de proporcionar un entorno claro y transparente para recuperar la confianza. El Perú, como un país emergente no ...

  16. Perceptions of per diems in the health sector: evidence and implications.

    Science.gov (United States)

    Vian, Taryn; Miller, Candace; Themba, Zione; Bukuluki, Paul

    2013-05-01

    Per diems are used to pay work-related expenses and motivate employees, yet they also can distort incentives and may be abused. This study was designed to explore perceptions of per diems among 41 high-, mid- and low-level government officers and non-governmental organization (NGO) officials in Malawi and Uganda. Interviews explored attitudes about per diems, benefits and problems for organizations and individuals, and risks and patterns of abuse. The study found that per diems provide benefits such as encouraging training, increasing staff motivation and supplementing salary. Despite these advantages, respondents voiced many discontents about per diems, stating that they create conflict, contribute to a negative organizational culture where people expect to be paid for all activities, and lead to negative changes in work time allocation. Work practices are also manipulated in order to maximize financial gain by slowing work, scheduling unnecessary trainings, or exaggerating time needed for tasks. Officials may appropriate per diems meant for others or engage in various forms of fraud for personal financial gain. Abuse seemed more common in the government sector due to low pay and weaker controls. A striking finding was the distrust that lower-level workers felt toward their superiors: allowances were perceived to provide unfair financial advantages to already better-off and well-connected staff. To curb abuse of per diems, initiatives must reduce pressures and incentives to abuse, while controlling discretion and increasing transparency in policy implementation. Donors can play a role in reform by supporting development of policy analysis tools, design of control mechanisms and evaluation of reform strategies.

  17. [Sequential digital dermatoscopic imaging. How much time is required per patient?].

    Science.gov (United States)

    Kofler, L; Egger, M; Kofler, H

    2014-05-01

    Melanoma screening is possible using the naked eye, a loupe, a dermatoscope or a sequential digital dermatoscopic imaging (SDDI) device. The latter provides photodocumentation and makes it possible to assess changes over time. One potential disadvantage of this method has been felt to be in the time expenditure per patient. Objective was to prospectively assess the time required for routine melanoma screening, using a SDDI device. All patients screened for melanoma using a SDDI system (Mole Max2) in a private dermatology practice during 1 year were included prospectively. The time needed per patient was measured. Suspicious lesions were excised and histologically evaluated. The number needed to treat (NNT) was calculated. Excisions performed exclusively due to cosmetic reasons were not included. 381 patients with 10,356 melanocytic lesions were documented using SDDI and clinically assessed (mean: 27.18 melanocytic lesions per patient; min:1, max:110). Mean time consumption per lesion was 15.4 s. (min:3, max:57) and per patient about 7 min. 98 suspicious lesions were excised, among them13 melanomas; yielding a NNT of 7.54. SDDI can be easily integrated into the daily routine; a variety of systems are available. The time required is reasonable, about 7 min per patient and about 15 s per lesion. The quality of the evaluation is operator-dependent; it can be evaluated by determining the NNT. A major advantage of this diagnostic procedure is the photodocumentation which makes it possible to assess potential progression of a melanocytic lesion.

  18. The NASA "PERS" Program: Solid Polymer Electrolyte Development for Advanced Lithium-Based Batteries

    Science.gov (United States)

    Baldwin, Richard S.; Bennett, William R.

    2007-01-01

    In fiscal year 2000, The National Aeronautics and Space Administration (NASA) and the Air Force Research Laboratory (AFRL) established a collaborative effort to support the development of polymer-based, lithium-based cell chemistries and battery technologies to address the next generation of aerospace applications and mission needs. The ultimate objective of this development program, which was referred to as the Polymer Energy Rechargeable System (PERS), was to establish a world-class technology capability and U.S. leadership in polymer-based battery technology for aerospace applications. Programmatically, the PERS initiative exploited both interagency collaborations to address common technology and engineering issues and the active participation of academia and private industry. The initial program phases focused on R&D activities to address the critical technical issues and challenges at the cell level. Out of a total of 38 proposals received in response to a NASA Research Announcement (NRA) solicitation, 18 proposals (13 contracts and 5 grants) were selected for initial award to address these technical challenges. Brief summaries of technical approaches, results and accomplishments of the PERS Program development efforts are presented. With Agency support provided through FY 2004, the PERS Program efforts were concluded in 2005, as internal reorganizations and funding cuts resulted in shifting programmatic priorities within NASA. Technically, the PERS Program participants explored, to various degrees over the lifetime of the formal program, a variety of conceptual approaches for developing and demonstrating performance of a viable advanced solid polymer electrolyte possessing the desired attributes, as well as several participants addressing all components of an integrated cell configuration. Programmatically, the NASA PERS Program was very successful, even though the very challenging technical goals for achieving a viable solid polymer electrolyte material or

  19. The Experience in Personal Social Systems Questionnaire (EXIS.pers): Development and Psychometric Properties.

    Science.gov (United States)

    Hunger, Christina; Bornhäuser, Annette; Link, Leoni; Geigges, Julian; Voss, Andreas; Weinhold, Jan; Schweitzer, Jochen

    2017-03-01

    This study presents the theoretical background, development, and psychometric properties of the German and English versions of the Experience in Personal Social Systems Questionnaire (EXIS.pers). It assesses how the members of a personal social system experience their situation within that system. It is designed as a research tool for interventions in which only one member of the system participates (e.g., Family Constellation Seminars). The EXIS.pers was created to measure change on the individual level relating to one's own important personal social system. In Study 1, we used exploratory factor analysis (EFA) for latent variable identification of the original German EXIS.pers (n = 179). In Studies 2 and 3, we used confirmatory factor analysis (CFA) to examine the dimensionality of the German (n = 634) and English (n = 310) EXIS.pers. Internal consistencies and cross-cultural structural equivalence were assessed. EFA indicated that a four-factor model provided best fit for the German EXIS.pers. For both the German and English EXIS.pers, CFA provided the best fit for a five-factor bi-level model that included a general factor (Experience In Personal Social Systems) and four dimensions (Belonging, Autonomy, Accord, Confidence). Good internal consistencies, external associations, and cross-cultural structural equivalence were demonstrated. This study provides first evidence for the German and English EXIS.pers as an economical and reliable measure of an individual's experience within his or her personal social systems. © 2016 Family Process Institute.

  20. Plants arrangement and number of seeds per hole in the agroeconomic yield of pea

    Directory of Open Access Journals (Sweden)

    Elissandra Pacito Torales

    2014-12-01

    Full Text Available The aim of this work was to study the ‘luciana 50’ pea, cultivated with different numbers of rows of plants in the plot and with two and three seeds per hill. The work carried out in Dourados-MS, between March-July 2010. Treatments were arranged in 3 x 2 factorial in randomized complete block design with six replicates. Populations corresponding to the sowing with two, three and four rows per plot were 264,000, 396,000 and 528,000 plants ha-1, respectively, with two seeds per hill, and 396,000, 594,000 and 792,000 plants ha-1, respectively, with three seeds per hill. The harvest was done at 108 days after sowing. In cultivation with four rows of plants and two seeds per hill, were obtained the highest yields of fresh and dry weight of grains and pods commercial, with increases of 29.88%, 33.85%, 29.14% and 32.22%, respectively, and higher number of grains and pods commercial, with increases of 28.13% and 27.12%, respectively, over two rows of plants with two seeds per hill. The highest yield of fresh weight of shoots, of bark and of non-commercial pods were with four rows of plants, with increases of 1.75 t ha-1, 0.44 t ha-1 and 0.47 t ha-1 respectively, compared to two rows. Considering the yield of commercial pods and grains and the estimated net income, it can be concluded that sowing of ‘Luciana 50’ pea should be performed with four rows of plants and two seeds per hill.

  1. Sviluppi di Ricevitori E di Componentistica Per Banda 3 mm Ad INAF-OA Cagliari

    Science.gov (United States)

    Navarrini, Alessandro

    2017-11-01

    L'INAF-OA Cagliari (OACa) sta sviluppando un ricevitore criogenico a basso rumore basato su un mixer SSB (Single Side Band) a superconduttore SIS (Superconductor-Insulator-Superconductor) per la banda 3 mm. Il ricevitore, acquistato da IRAM, è stato fortemente modificato per essere adattato al fuoco Gregoriano di SRT (Sardinia Radio Telescope). Lo strumento è caratterizzato da una nuova criogenia a ciclo chiuso 4 K (per evitare l'uso di elio liquido in antenna), da un nuovo oscillatore locale (di tipo ALMA Banda 3) e da un nuovo sistema di controllo e di monitoraggio basato su schede Raspberry ed Arduino sviluppato ad OACa. Verranno presentati i recenti sviluppi sul ricevitore, inclusi i risultati preliminari della misura della temperatura di rumore, che raggiunge un valore pari a Trec=66 K alla frequenza di 86 GHz, nonostante la criogenia non sia ancora ottimizzata. L'INAF-OACa è coinvolto nel progetto AETHRA (Advanced European Technologies for Heterodyne Receivers for Astronomy) nel quadro del programma Radionet/Horizon2020 per il quale sta contribuendo al WP1 (Work Package 1). Lo scopo del WP1 è di sviluppare e costruire un dimostratore di un array di ricevitori a doppia polarizzazione per la banda 3 mm basato su amplificatori criogenici a basso rumore (LNA) in tecnologia a semiconduttore MMIC. Nell'ambito del WP1 l'OACa ha in carico il progetto di un OrthomodeTransducer (OMT) in guida d'onda o in tecnologia planare per la banda 72-116 GHz che sia integrabile con amplificatori MMICs ed adatto all'integrazione in un array da installare nel piano focale di un radiotelescopio. Verranno presentati i design preliminari degli OMT per AETHRA, che sono basati su prototipi sviluppati in passato da OACa.

  2. Chi ha paura dei libri per bambini/e? I presupposti della critica: una questione politica

    Directory of Open Access Journals (Sweden)

    Giulia Zanfabro

    2015-11-01

    Full Text Available Nella definizione di ciò che si considera letteratura per l’infanzia la centralità del pubblico cui questa letteratura si rivolge è una questione critica fondamentale: la letteratura per l’infanzia è, infatti, una categoria di libri la cui esistenza dipende da una serie di supposte relazioni con un particolare pubblico, quello dei/delle bambini/e (Lesnik-Oberstein 2002: 15. L’articolo è strutturato in tre parti: i nella prima parte situerò la letteratura per l’infanzia all’interno del sistema letterario contemporaneo e renderò esplicita l’asimmetria tra la letteratura – e, di conseguenza, tutti gli/le agenti coinvolti/e nella sua produzione e nella sua distribuzione – e i/le bambini/e – che occupano, dall’altro lato, il posto della ricezione; ii nella seconda parte cercherò di esplicitare il contenuto dei presupposti della maggior parte della critica che si occupa di letteratura per l’infanzia e le idee di bambino/a (e di letteratura da cui essi dipendono; iii nella terza e ultima parte renderò esplicite le ragioni per cui mettere in questione questi presupposti è una questione politica: le argomentazioni di quelle forze politiche che, in Italia, vogliono limitare e censurare la diffusione di libri per bambini/e come Piccolo Uovo si basano, infatti, proprio sugli stessi presupposti di gran parte della critica che si occupa di letteratura per l’infanzia, soprattutto di quella che si situa in ambito pedagogico.

  3. GDP PER CAPITA, PROTEST INTENSITY AND REGIME TYPE: A QUANTITATIVE ANALYSIS

    Directory of Open Access Journals (Sweden)

    A. V. Korotayev

    2016-01-01

    Full Text Available The study suggests that the relationship between per capita GDP and intensity of antigovernment demonstrations is not negative as tends to be believed; we are rather dealing with an inverted U-shaped relationship: the highest levels of antigovernment demonstration intensity are typical for countries with neither the lowest nor the highest values of GDP per capita, but rather with intermediate values of this indicator. Thus, for higher values of per capita GDP we observe a negative correlation between GDP per capita and the antigovernment demonstration intensity, and for lower values it is positive. This correlation is partly explained by the following points: (1 GDP growth in authoritarian regimes leads to increased pro-democracy movement, and hence to intensifi cation of the anti-government demonstrations. And since in our database (as well as in reality authoritarian states constitute a very high percentage of the number of states with the lowest values of per capita income, the effect of the growth of internal pressure on authoritarian regimes towards democracy with economic growth to some extent (but no not completely explains a strong correlation between GDP per capita and the intensity of antigovernment demonstrations for low and middle income countries. (2 In the range of per capita GDP up to $ 20000, the increase in per capita GDP is quite strongly correlated with a decrease in the proportion of authoritarian regimes and the increasing share of nonauthoritarian regimes (democratic and intermediate. The presence of non-authoritarian regimes in this range is signifi cantly positively correlated with the higher intensity of anti-government demonstrations. This is another mechanism that contributes to the presence of a strong positive correlation between GDP per capita and the intensity of anti-government demonstrations in the range of interest to us. At the same time we have done a further analysis that has

  4. Exploration of two Canadian greenhouse gas emissions targets : 25 per cent below 1990 and 20 per cent below 2006 levels by 2020 : final report

    Energy Technology Data Exchange (ETDEWEB)

    Bataille, C.; Wolinetz, M.; Peters, J.; Bennett, M.; Rivers, N. [MK Jaccard and Associates, Vancouver, BC (Canada)

    2009-10-18

    This study reviewed the feasibility and cost of 2 levels of greenhouse gas (GHG) emissions reductions in Canada, with particular reference to an environmental non-governmental organization (ENGO) that recommended 25 per cent reduction in GHG emissions below 1990 levels by 2020, and the Canadian government's recommended 20 per cent reduction of GHGs from 2006 levels by 2020. A CIMS hybrid technology simulation tool and a static computable general equilibrium (CGE) model were used to conduct the analysis. The study showed that current carbon charge and other complementary policies will not meet required targets for either the current governmental reduction plan or the ENGO plan. Recommended actions to provide emissions reductions included carbon capture and storage (CCS) technology implementation; increased energy efficiency in the personal and freight transportation sectors; increased GHG control in the upstream oil and gas industry and of landfill gas; and the use of international permit purchases. Other recommendations included switching to electricity and using renewable energy sources within the electricity industry. 11 refs., 98 tabs., 16 figs.

  5. Ús de tecnologies de tinta digital per a facilitar la interacció professor-alumnes en un curs d'alemany per a enginyers

    Directory of Open Access Journals (Sweden)

    Daniela Gil Salom

    2015-12-01

    Full Text Available Aprendre una llengua usant la tauleta i la tinta digital com a mitjà de comunicació amb el professor i amb els altres companys, aporta acció i, en conseqüència, també motivació, al procés d'ensenyança-aprenentatge. Si el discent té més oportunitats de participar en l'aula per mitjà de l'ús d'esta ferramenta, pot millorar el seu aprenentatge de la llengua alemanya? Esta és la pregunta que pretenem respondre amb la nostra investigació. Les dades obtinguts mostren la conveniència d'aprofitar estes tecnologies, ja que l'atenció prestada a tres elements lingüístics fonamentals en l'aprenentatge de la llengua alemanya per mitjà de la tinta digital i el programari lliure Classroom Presenter ha oferit bons resultats, tant en les proves diagnòstiques, com en la valoració expressada pels estudiants.

  6. Analysis of per capita income dynamics of the USA and Russia gross domestic product

    Directory of Open Access Journals (Sweden)

    Igor' Il'ich Pichurin

    2012-09-01

    Full Text Available This paper represents a judgment that the relator of per capita income of the countries is a rough indicator of the ratio of labor productivity in these countries. Accordingly, the analysis of the dynamics of per capita income in the United States and Russia for the period from 1861 to present time is made. The described statistical data shows that the ratio of per capita income in the U. S. and Russia has not changed from 1861 to 1913. Consequently, the nowadays widespread claim that capitalist development in Russia led the country into the category of rapidly developing countries for 50 years after the abolition of serfdom is not true. The gap in labor productivity in Russia compared to the United States, Germany, Britain and other developed countries remained unchanged. The sharp decline in per capita income was based on the country's industrialization and appropriate agricultural sphere mechanization. As a result, the gap has narrowed to the mid-sixties of the XX century up to two times, despite the fact those ten years of this period fell out from the normal development in connection with the Second World War and post-war reconstruction of the nationaleconomy. After thecollapse of thesocialisteconomy, this gap increased up to fivetimes in 2000, and now after the first decade of the XXI century it is about threetimes. Thereasons for these changes in respect to per capita income are analyzed in this paper.

  7. USP2 Regulates the Intracellular Localization of PER1 and Circadian Gene Expression

    DEFF Research Database (Denmark)

    Yang, Yaoming; Duguay, David; Fahrenkrug, Jan

    2014-01-01

    Endogenous 24-h rhythms in physiology are driven by a network of circadian clocks located in most tissues. The molecular clock mechanism is based on feedback loops involving clock genes and their protein products. Posttranslational modifications, including ubiquitination, are important for regula......Endogenous 24-h rhythms in physiology are driven by a network of circadian clocks located in most tissues. The molecular clock mechanism is based on feedback loops involving clock genes and their protein products. Posttranslational modifications, including ubiquitination, are important...... that USP2 regulates nucleocytoplasmic shuttling and nuclear retention of PER1 and its repressive role on the clock transcription factors CLOCK and BMAL1. The rhythm of nuclear entry of PER1 in Usp2 knockout mouse embryonic fibroblasts (MEFs) was advanced but with reduced nuclear accumulation of PER1....... Although Per1 mRNA expression rhythm remained intact in the Usp2 KO MEFs, the expression profiles of other core clock genes were altered. This was also true for the expression of clock-controlled genes (e.g., Dbp, Tef, Hlf, E4bp4). A similar phase advance of PER1 nuclear localization rhythm and alteration...

  8. The relationship between limit of Dysphagia and average volume per swallow in patients with Parkinson's disease.

    Science.gov (United States)

    Belo, Luciana Rodrigues; Gomes, Nathália Angelina Costa; Coriolano, Maria das Graças Wanderley de Sales; de Souza, Elizabete Santos; Moura, Danielle Albuquerque Alves; Asano, Amdore Guescel; Lins, Otávio Gomes

    2014-08-01

    The goal of this study was to obtain the limit of dysphagia and the average volume per swallow in patients with mild to moderate Parkinson's disease (PD) but without swallowing complaints and in normal subjects, and to investigate the relationship between them. We hypothesize there is a direct relationship between these two measurements. The study included 10 patients with idiopathic PD and 10 age-matched normal controls. Surface electromyography was recorded over the suprahyoid muscle group. The limit of dysphagia was obtained by offering increasing volumes of water until piecemeal deglutition occurred. The average volume per swallow was calculated by dividing the time taken by the number of swallows used to drink 100 ml of water. The PD group showed a significantly lower dysphagia limit and lower average volume per swallow. There was a significantly moderate direct correlation and association between the two measurements. About half of the PD patients had an abnormally low dysphagia limit and average volume per swallow, although none had spontaneously related swallowing problems. Both measurements may be used as a quick objective screening test for the early identification of swallowing alterations that may lead to dysphagia in PD patients, but the determination of the average volume per swallow is much quicker and simpler.

  9. Circadian Clock Model Supports Molecular Link Between PER3 and Human Anxiety.

    Science.gov (United States)

    Liberman, Amanda R; Kwon, Soo Bin; Vu, Ha T; Filipowicz, Allan; Ay, Ahmet; Ingram, Krista K

    2017-08-31

    Generalized anxiety and major depression have become increasingly common in the United States, affecting 18.6 percent of the adult population. Mood disorders can be debilitating, and are often correlated with poor general health, life dissatisfaction, and the need for disability benefits due to inability to work. Recent evidence suggests that some mood disorders have a circadian component, and disruptions in circadian rhythms may even trigger the development of these disorders. However, the molecular mechanisms of this interaction are not well understood. Polymorphisms in a circadian clock-related gene, PER3, are associated with behavioral phenotypes (extreme diurnal preference in arousal and activity) and sleep/mood disorders, including seasonal affective disorder (SAD). Here we show that two PER3 mutations, a variable number tandem repeat (VNTR) allele and a single-nucleotide polymorphism (SNP), are associated with diurnal preference and higher Trait-Anxiety scores, supporting a role for PER3 in mood modulation. In addition, we explore a potential mechanism for how PER3 influences mood by utilizing a comprehensive circadian clock model that accurately predicts the changes in circadian period evident in knock-out phenotypes and individuals with PER3-related clock disorders.

  10. The clock gene PER2 and sleep problems: association with alcohol consumption among Swedish adolescents.

    Science.gov (United States)

    Comasco, Erika; Nordquist, Niklas; Göktürk, Camilla; Aslund, Cecilia; Hallman, Jarmila; Oreland, Lars; Nilsson, Kent W

    2010-02-01

    Alcohol abuse is associated with sleep problems, which are often linked to circadian rhythm disturbances. Previous studies have separately examined the effects of mutations in the clock gene PER2 on alcohol consumption and sleep problems. Here we hypothesized that an allelic variation in the PER2 gene is associated with alcohol consumption in interaction with sleep problems among adolescents. The Survey of Adolescent Life and Health in Västmanland 2006, a Swedish county, including 1254 students 17-18 years old, was used as a population-representative sample of adolescents. We investigated the PER2 Single Nucleotide polymorphism (SNP) 10870 (A/G) in the cohort together with an assessment of alcohol consumption according to the AUDIT-C questionnaire, and sleep problems using a survey consisting of 18 items. Furthermore, we carried out an exploratory analysis on the PER2 Single Nucleotide Polymorphism 10870 polymorphism in a group of severely alcoholic females. We found a significant association of the SNP 10870 in adolescent boys, where the genotype AA, in the presence of several and frequent sleep problems, was associated with increased alcohol consumption. Among adolescent girls, only sleep problems were related to alcohol consumption. A non-significant trend was observed among the severely alcoholic females, with the G allele being over-represented in the severely alcoholic females group in comparision to the control females. These results indicate that PER2 gene variation is associated with alcohol consumption in interaction with sleep problems among Swedish adolescent boys.

  11. Identità visiva e narrazione in un percorso MOOC per docenti

    Directory of Open Access Journals (Sweden)

    Letizia Cinganotto

    2015-09-01

    Full Text Available Il contributo mira a illustrare un esempio di MOOC per docenti realizzato in un contesto internazionale. In particolare, il focus è rappresentato dalla documentazione e riflessione sul percorso formativo dei docenti attraverso l’uso del diario, componente essenziale per la rielaborazione e reinterpretazione dell’esperienza ai fini dell’arricchimento e della crescita personale e professionale. Le tecnologie multimediali e multimodali offrono la possibilità di costruire varie tipologie di diari all’interno di percorsi di formazione online. In particolare, verranno presi in considerazione alcuni esempi di diari e ne saranno illustrate le caratteristiche principali, dettagliando l’uso di alcuni tool per la rappresentazione narrativa e visiva. L’articolo prende le mosse da un breve quadro di riferimento teorico sulla funzione dei MOOC nella formazione dei docenti e sull’importanza della meta-riflessione ai fini della costruzione del profilo del “professionista riflessivo”.

  12. Registro adicional de Langea euprosopides (Coleoptera: Cicindelidae para el Perú

    Directory of Open Access Journals (Sweden)

    Abdhiel Arnaldo Bustamante-Navarrete

    2016-12-01

    Full Text Available Se registra un nuevo espécimen de Langea euprosopides W. Horn, 1901 en la región Cusco (Perú. El género Langea W. Horn contiene tres especies. Debido a la falta de observaciones de miembros de este género en su ambiente natural, se desconocen sus hábitos, ciclo biológico y sus estadios de ciclo de vida. El género es aparentemente endémico del Perú. Se presentan algunos datos sobre el posible sustrato de captura y un mapa de distribución de la especie en el Perú.

  13. NASA Green Flight Challenge: Conceptual Design Approaches and Technologies to Enable 200 Passenger Miles per Gallon

    Science.gov (United States)

    Wells, Douglas P.

    2011-01-01

    The Green Flight Challenge is one of the National Aeronautics and Space Administration s Centennial Challenges designed to push technology and make passenger aircraft more efficient. Airliners currently average around 50 passenger-miles per gallon and this competition will push teams to greater than 200 passenger-miles per gallon. The aircraft must also fly at least 100 miles per hour for 200 miles. The total prize money for this competition is $1.65 Million. The Green Flight Challenge will be run by the Comparative Aircraft Flight Efficiency (CAFE) Foundation September 25 October 1, 2011 at Charles M. Schulz Sonoma County Airport in California. Thirteen custom aircraft were developed with electric, bio-diesel, and other bio-fuel engines. The aircraft are using various technologies to improve aerodynamic, propulsion, and structural efficiency. This paper will explore the feasibility of the rule set, competitor vehicles, design approaches, and technologies used.

  14. Multiuser switched scheduling systems with per-user threshold and post-user selection

    KAUST Repository

    Nam, Haewoon

    2010-06-01

    A multiuser switched diversity scheduling scheme with per-user feedback threshold is proposed in this paper. Unlike the conventional multiuser switched diversity scheduling scheme where a single threshold is used by all the users in order to determine whether to transmit a feedback, the proposed scheme deploys per-user threshold, where each user uses a potentially different threshold than other users thresholds. This paper first provides a generic analytical framework for the optimal feedback thresholds in a closed form. Then we investigates the impact of user sequence strategies and post selection strategies on the performance of the multiuser switched scheduling scheme with per-user threshold. Numerical and simulation results show that the proposed scheme provides a higher system capacity compared to the conventional scheme. © 2010 IEEE.

  15. Nuevos registros de peces costeros tropicales para el Perú

    Directory of Open Access Journals (Sweden)

    Yuri Hooker

    2011-07-01

    Full Text Available En el presente trabajo se dan a conocer 11 nuevos registros de peces marinos para el Perú. Las colectas fueron efectuadas entre los años 1989 y 2007 en las localidades de Bocapan, Canoas de Punta Sal, Punta Sal (Tumbes; Los Órganos, Isla Foca (Piura; Islas Lobos de Afuera (Lambayeque; Bahía Samanco (Ancash; y Pucusana (Lima. Los nuevos registros para la ictiofauna marina del Perú son: Dasyatis longa, Urobatis halleri, Cephalopholis panamensis, Prognathodes carlhubbsi, Cirrhitus rivulatus, Stegastes beebei, Thalassoma lucasanum, Thalassoma grammaticum, Axoclinus lucillae, Elacatinus punticulatus y Coryphopterus urospilus. Las especies Cirrhitichthys oxycephalus, Lythrypnus dalli y Myripristis leiognathus, fueron anteriormente mencionadas para Perú pero sin existir registros documentados, con la presente publicación se certifica su presencia. Se discute sobre características biogeográficas y ampliación de distribución durante El Niño.

  16. Strutturazione dell’A.I.M. [Archivio informativo multimediale] per il progetto

    Directory of Open Access Journals (Sweden)

    Cristiana Bartolomei

    2011-06-01

    Full Text Available Il nostro obiettivo è quello di individuare e integrare una serie di tecnologie e strategie operative per la creazione di un’architettura digitale di ultima generazione, in grado di fornire un archivio informativo multimediale (A.I.M. virtualmente illimitato e scalabile per files multimediali multi formato (foto, disegni ecc. e modelli 3D. Sostanzialmente, si tratta di applicazioni di Database: tutti i beni considerati devono essere “inventariati” in modo opportuno e queste schede di inventario devono essere organizzate in modo utile. L’obiettivo dello strumento A.I.M. è dimostrare che è possibile integrare diverse fonti d’informazioni, continuamente aggiornabili e dotate di una specifica interfaccia di gestione e di ricerca, destinate a supportare dinamicamente il livello divulgativo e informativo e vuole rappresentare, per restauratori, conservatori e gestori in genere dei beni culturali, un valido strumento di monitoraggio dei restauri.

  17. Optimal Multiuser Zero Forcing with Per-Antenna Power Constraints for Network MIMO Coordination

    Directory of Open Access Journals (Sweden)

    Kaviani Saeed

    2011-01-01

    Full Text Available We consider a multicell multiple-input multiple-output (MIMO coordinated downlink transmission, also known as network MIMO, under per-antenna power constraints. We investigate a simple multiuser zero-forcing (ZF linear precoding technique known as block diagonalization (BD for network MIMO. The optimal form of BD with per-antenna power constraints is proposed. It involves a novel approach of optimizing the precoding matrices over the entire null space of other users' transmissions. An iterative gradient descent method is derived by solving the dual of the throughput maximization problem, which finds the optimal precoding matrices globally and efficiently. The comprehensive simulations illustrate several network MIMO coordination advantages when the optimal BD scheme is used. Its achievable throughput is compared with the capacity region obtained through the recently established duality concept under per-antenna power constraints.

  18. Psicohistoria y formas histórico generales de la personalidad en el Perú

    OpenAIRE

    Paredes Ruiz, Santiago; Facultad de Psicología, Universidad Nacional Mayor de San Marcos, Lima, Perú

    2014-01-01

    El presente artículo es una síntesis de las investigaciones teóricas y metodológicas de las formas histórico generales de la personalidad en el Perú, esto es desarrollado desde los campos de la psicohistoria y neurociencias. Se plantea y desarrolla la categoría de formas histórico generales de la personalidad. Se explica su devenir en la evolución de los hombres del Perú, desde la época prehispánica hasta el período republicano, incluyendo la Colonia. Los datos históricos y sociales de cada é...

  19. A diagram for defined solar radiation absorbed per unit area of flat plate solar collectors

    Energy Technology Data Exchange (ETDEWEB)

    Tekin, Y.; Altuntop, N. [Erciyes University, Dept. of Mechanical Engineering (Turkey); Cengel, Y.A. [Nevada Reno University, Dept. of Mechanical Engineering, NV (United States); Cengel, Y.A. [Nevada University, Dept. Mechanical Engineering, Reno, NV (United States)

    2000-07-01

    In Erciyes University, the Solar House (28.75 m{sup 2}) is heated from the floor by using flat plate liquid solar collectors. Required solar radiation for heating and heat losses are calculated. In this work, the required calculations for Erciyes Solar House were generalized and required calculation were done to evaluate absorbed solar radiation per unit surface of the flat plate liquid collector. At the end, three generalized diagrams for nine different months are obtained using obtained numerical values. The goal of preparing diagrams is to determine absorbed solar radiation per unit surface area of flat plate liquid collector at any instant at any latitude, In this work, the diagram is explained by means of sample calculations for November. This diagram was prepared to find out absorbed solar radiation per unit area of black surface collector by means obtained equations. With this diagram, all instant solar radiation can be evaluated in 19 steps. (authors)

  20. Using data on resistance prevalence per sample in the surveillance of antimicrobial resistance

    DEFF Research Database (Denmark)

    Vieira, Antonio; Shuyu, Wu; Jensen, Lars Bogø

    2008-01-01

    Objectives: In most existing antimicrobial resistance monitoring programmes, one single bacterial colony from each collected sample is susceptibility tested against a panel of antimicrobials. Detecting the proportion of colonies resistant to different antimicrobials in each sample can provide...... quantitative data on antimicrobial resistance (resistance prevalence per sample). Methods: In this study, a total of 98 faecal samples from slaughter pigs were tested for tetracycline and sulphonamide resistance in Escherichia coli using the single colony method, and these results were compared...... with the results obtained using the resistance prevalence per sample method. Results: The results obtained by the resistance prevalence per sample method showed a lower occurrence of resistance. Tetracycline resistance in E. coli was found in 36.7% of the samples using the single colony method, while the mean...

  1. Energy consumptions per sector; Les consommations d'energie par secteur

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This document presents the energy consumption data of France per energy type and sector of use in the form of tables and graphics for the last decade and sometimes before: 1 - residential and tertiary sector: energy consumption per energy source, energy consumption per use (coal, heavy and domestic fuels, natural gas, LPG (butane, propane), electricity), comparison of the share of each energy source between 1973 and 2003, 20 years of space heating data in main dwellings (1982-2002), district heating networks from 1987 to 1997; 2 - transportation sector: fuel consumption of individual cars in France (1990-2003, 1990-2002, 1990-2001, 1987-1999), some indicators about the energy consumption in transports in France (2000-2001); 3 - industry sector: consumption of fuel substitutes in the cement industry in 2001, importance and limitations. (J.S.)

  2. NOTE - Minimum number of common bean plants per plot to assess field resistance to white mold

    Directory of Open Access Journals (Sweden)

    uliana Andrade Dias

    2011-01-01

    Full Text Available This study aimed to determine the minimum number of plants per plot to assess the field resistance in common beanto white mold. Thirteen cultivars were inoculated with six isolates of Sclerotinia sclerotiorum and evaluated in a randomized blockdesign with three replications and plots consisting of 1-m rows with 15 plants. Plants were inoculated by the straw test as proposedby Petzoldt and Dickson (1996, to evaluate partial resistance in a greenhouse. Eight days after inoculation the disease severity wasevaluated on a 1-9 diagrammatic scale, where 1 = asymptomatic plants to 9 = plant death. To determine the minimum number ofplants per plot, the following methods were used: maximum curvature, segmented linear model, quadratic segmented model and therelative CV model. There were significant differences among cultivars and isolates and no significant cultivar - isolate interaction.It was observed that eight plants per plot is an adequate number to assess the reaction of common bean to white mold.

  3. A telemanipulator's direct manipulation interface; Interfaccia a manipolazione diretta per un telemanipolatore

    Energy Technology Data Exchange (ETDEWEB)

    Zirilli, P.; Levialdi, S. [Rome Univ. La Sapienza, Rome (Italy). Dipt. Scienze dell' Informazione; Manzano, J.L. [ENEA, Centro Ricerche Casaccia, S. Maria di Galeria, RM (Italy). Dipt. Innovazione

    1999-07-01

    The report discusses the analysis results of the interface of the ENEA's (National Agency for New Technology, Energy and the Enumerative) telemanipulator Mascot. A criterion to measure the u suability of an interface and a paradigm to manipulate objects in a virtual environment using devices without force feedback are proposed. A prototype for the Mascot's interface and a simulator of the telemanipulator are described. [Italian] Vengono presentati i risultati dell'analisi dell'interfaccia Mascot, un telemanipolatore sviluppato dall'ENEA. Si introduce un criterio di complessita' per misurare l'uso di un'interfaccia e si propone un paradigma per l'interazione con ambienti virtuali, applicabili alla manipolazione di oggetti tramite dispositivi che non forniscono controreazione di forza. Si descrive infine la realizzazione di un prototipo di un'interfaccia e di un simulatore per l'utilizzo del telemanipolatore.

  4. Age-dependent alterations in human PER2 levels after early morning blue light exposure.

    Science.gov (United States)

    Jud, Corinne; Chappuis, Sylvie; Revell, Victoria L; Sletten, Tracey L; Saaltink, Dirk-Jan; Cajochen, Christian; Skene, Debra J; Albrecht, Urs

    2009-10-01

    In our modern society, we are exposed to different artificial light sources that could potentially lead to disturbances of circadian rhythms and, hence, represent a risk for health and welfare. Investigating the acute impact of light on clock-gene expression may thus help us to better understand the mechanisms underlying disorders rooted in the circadian system. Here, we show an overall significant reduction in PER2 expression in oral mucosa with aging in the morning, noon, and afternoon. In the afternoon, 10 h after exposure to early morning blue light, PER2 was significantly elevated in the young compared to green light exposure and to older participants. Our findings demonstrate that human buccal samples are a valuable tool for studying clock-gene rhythms and the response of PER2 to light. Additionally, our results indicate that the influence of light on clock-gene expression in humans is altered with age.

  5. Reporte de valorización Inretail Perú Corp

    OpenAIRE

    Lezama Benavides, Aldo; Salinas Ríos, Pedro; Koo Quispe, William

    2015-01-01

    El presente documento corresponde a la valoración del Holding InRetail Perú Corp. a través del método de Flujo de Caja Descontado. InRetail Perú Corp. (en adelante InRetail o la compañía), es un conglomerado de empresas líderes en el sector retail y cuyas operaciones se concentran en Perú a través de tres unidades de negocio: supermercados, farmacias y centros comerciales. Asimismo, sobre la base de sus productos y servicios, la compañía se encuentra organizada en dos grupos: (i) InRetail Con...

  6. Velocity of sound measurements in gaseous per-fluorocarbons and their custom mixtures

    CERN Document Server

    Vacek, V; Lindsay, S

    2000-01-01

    An inexpensive sonar instrument was prepared for measurements of sound velocity in two fluorocarbon vapors; per-fluoro-n-propane (C3F8), per-fluoro-n-butane (C4F10), and their custom mixtures. The apparatus, measurement principle and instrument software are described. All sound velocity measurements in per-fluorocarbons were made in the low pressure range between 0.01 and 0.4 MPa, and at temperatures between 253 and 303 K. The purity of the C3F8 and C4F10 samples was checked using gas chromatography. Uncertainties in the speed of sound measurements were better than ± 0.1 %. Comparisons were made with theoretical predictions of sound velocity for the two individual components. The instrument was then used for concentration monitoring of custom C3F8/C4F10 mixtures.

  7. Equinodermos de las Islas Lobos de Afuera (Lambayeque, Perú

    Directory of Open Access Journals (Sweden)

    Yuri Hooker

    2013-05-01

    Full Text Available Del 19 al 24 de junio de 1999 se llevó a cabo una expedición para realizar el inventario rápido de los equinodermos de las Islas Lobos de Afuera (06°55,5 S - 80°42,5 W. Se colectó un total de 39 especies de equinodermos: 7 asteroideos (2 nuevos registros para el Perú: Luidia bellonae, Luidia brevispina; 8 ofiuroideos (1 nuevo registro para el Perú: Ophionereis sp.; 11 equinoideos (5 nuevos registros para el Perú: Astropyga pulvinata, Diadema mexicanum, Lytechinus sp., Toxopneustes roseus, Tripneustes depressus y 13 holoturoideos (6 nuevos registros: Psolidium dorsipes, Cucumaria flamma, Pseudocnus californicus, Holothuria sp., Chiridota sp. y Actinopyga sp..

  8. Castelli di carta. La piega per la costruzione di superfici articolate

    Directory of Open Access Journals (Sweden)

    Andrea Casale

    2012-06-01

    Full Text Available L’antica arte del piegare la carta, l’Origami, sta vivendo un rinnovato interesse che coinvolge molti aspetti della ricerca.  Con il termine origami, si intende lo studio del modo di piegare il foglio di carta per imporgli una specifica forma.  La superficie tassellata per mezzo di specifiche pieghe, si propone come un nuovo soggetto di studio: la superficie piegata articolata. La forma congiunta al movimento, assume un particolare interesse nella contemporanea ricerca geometrica e architettonica. Il panorama contemporaneo, propone opere di architettura “responsiva”, capaci di modificare le proprie caratteristiche per adeguarsi a nuove condizioni. La superficie piegata articolata sembra particolarmente adatta a descrivere questo modo d’intendere l’architettura, reagendo a diverse volontà e di conseguenza modificando la propria conformazione attraverso un attento controllo progettuale della forma.

  9. Sviluppo e valutazione di test diagnostici per la sierodiagnosi di brucellosi suina

    Directory of Open Access Journals (Sweden)

    Tiziana Di Febo

    2012-06-01

    Full Text Available Sono stati sviluppati una ELISA competitiva (c-ELISA, una ELISA indiretta (i-ELISA e un test immunologico DELFIA (Dissociation-Enhanced Lanthanide Fluorescence Immunoassay per la ricerca di anticorpi verso Brucella suis in sieri di maiale e cinghiale. I tre test prevedono l’utilizzo di un anticorpo monoclonale (MAb 4B5A verso l’LPS di Brucella (c-ELISA e DELFIA e di un anticorpo monoclonale (MAb 10C2G5 verso le IgG suine (i-ELISA. La specificità (Sp e la sensibilità (Se dei tre test sono le seguenti: per la c-ELISA Se e Sp = 100% con un valore di cut-off pari al 61.0% (B/B0%; per la i-ELISA Sp = 99.1% e Se = 100% con un valore di cut-off di 21.7% (PP%; per il DELFIA Sp = 91.0% e Se = 75% ponendo il valore di cut-off al 37.0% (B/B0%. Inoltre sono state valutate le performance, nei confronti di sieri suini, di un test FPA (Fluorescence Polarization Assay commerciale sviluppato per la ricerca di anticorpi anti-Brucella in sieri bovini; la specificità e la sensibilità ottenute sono entrambe del 100% al valore di cut-off di 99.5 (mP. Questi risultati suggeriscono che la combinazione di c-ELISA, i-ELISA e FPA può essere utilizzata per migliorare la diagnosi di brucellosi suina.

  10. Maxillaria jostii Dodson (Orchidaceae un nuevo registro para la Flora del Perú

    Directory of Open Access Journals (Sweden)

    Eric F. Rodríguez Rodríguez

    2013-12-01

    Full Text Available Se presenta a Maxillaria jostii Dodson (Orchidaceae como una nueva adición a la Flora del Perú procedente de los substratos de roca arenisca de la Cordillera subandina de Huarango (provincia San Ignacio, departamento Cajamarca, una prolongación sureña de la Cordillera del Cóndor rica en especies. Maxillaria jostii ha sido considerada como una especie endémica para Ecuador (Zamora-Chinchipe, Morona-Santiago; sin embargo, con el presente estudio se amplía su distribución geográfica hacia el Perú. Esta nueva contribución al conocimiento de la flora del país es el resultado del trabajo de campo y de herbario, gracias al Proyecto Binacional «Inventario Botánico de la Región de la Cordillera del Cóndor, Ecuador y Perú, 2005-2007», desarrollado entre las instituciones: MO, HUT, LOJA y QCNE. La contrastación específica se realizó con las especies documentadas en el «Catálogo de las Angiospermas y Gimnospermas del Perú» (Brako & Zarucchi 1993, «Diez años de adiciones a la flora del Perú: 1993-2003» (Ulloa Ulloa et al. 2004 y «Nuevas Adiciones de Angiospermas a la Flora del Perú» (Rodríguez et al. 2006b.

  11. Melatonin Entrains PER2::LUC Bioluminescence Circadian Rhythm in the Mouse Cornea.

    Science.gov (United States)

    Baba, Kenkichi; Davidson, Alec J; Tosini, Gianluca

    2015-07-01

    Previous studies have reported the presence of a circadian rhythm in PERIOD2::LUCIFERASE (PER2::LUC) bioluminescence in mouse photoreceptors, retina, RPE, and cornea. Melatonin (MLT) modulates many physiological functions in the eye and it is believed to be one of the key circadian signals within the eye. The aim of the present study was to investigate the regulation of the PER2::LUC circadian rhythm in mouse cornea and to determine the role played by MLT. Corneas were obtained from PER2::LUC mice and cultured to measure bioluminescence rhythmicity in isolated tissue using a Lumicycle or CCD camera. To determine the time-dependent resetting of the corneal circadian clocks in response to MLT or IIK7 (a melatonin type 2 receptor, MT2, agonist) was added to the cultured corneas at different times of the day. We also defined the location of the MT2 receptor within different corneal layers using immunohistochemistry. A long-lasting bioluminescence rhythm was recorded from cultured PER2::LUC cornea and PER2::LUC signal was localized to the corneal epithelium and endothelium. MLT administration in the early night delayed the cornea rhythm, whereas administration of MLT at late night to early morning advanced the cornea rhythm. Treatment with IIK7 mimicked the MLT phase-shifting effect. Consistent with these results, MT2 immunoreactivity was localized to the corneal epithelium and endothelium. Our work demonstrates that MLT entrains the PER2::LUC bioluminescence rhythm in the cornea. Our data indicate that the cornea may represent a model to study the molecular mechanisms by which MLT affects the circadian clock.

  12. Moles of a Substance per Cell Is a Highly Informative Dosing Metric in Cell Culture.

    Directory of Open Access Journals (Sweden)

    Claire M Doskey

    Full Text Available The biological consequences upon exposure of cells in culture to a dose of xenobiotic are not only dependent on biological variables, but also the physical aspects of experiments e.g. cell number and media volume. Dependence on physical aspects is often overlooked due to the unrecognized ambiguity in the dominant metric used to express exposure, i.e. initial concentration of xenobiotic delivered to the culture medium over the cells. We hypothesize that for many xenobiotics, specifying dose as moles per cell will reduce this ambiguity. Dose as moles per cell can also provide additional information not easily obtainable with traditional dosing metrics.Here, 1,4-benzoquinone and oligomycin A are used as model compounds to investigate moles per cell as an informative dosing metric. Mechanistic insight into reactions with intracellular molecules, differences between sequential and bolus addition of xenobiotic and the influence of cell volume and protein content on toxicity are also investigated.When the dose of 1,4-benzoquinone or oligomycin A was specified as moles per cell, toxicity was independent of the physical conditions used (number of cells, volume of medium. When using moles per cell as a dose-metric, direct quantitative comparisons can be made between biochemical or biological endpoints and the dose of xenobiotic applied. For example, the toxicity of 1,4-benzoquinone correlated inversely with intracellular volume for all five cell lines exposed (C6, MDA-MB231, A549, MIA PaCa-2, and HepG2.Moles per cell is a useful and informative dosing metric in cell culture. This dosing metric is a scalable parameter that: can reduce ambiguity between experiments having different physical conditions; provides additional mechanistic information; allows direct comparison between different cells; affords a more uniform platform for experimental design; addresses the important issue of repeatability of experimental results, and could increase the

  13. Dose per unit area - a study of elicitation of nickel allergy

    DEFF Research Database (Denmark)

    Fischer, Louise Arup; Menné, Torkil; Johansen, Jeanne Duus

    2007-01-01

    BACKGROUND: Experimental sensitization depends upon the amount of allergen per unit skin area and is largely independent of the area size. OBJECTIVES: This study aimed at testing if this also applies for elicitation of nickel allergy. PATIENTS/METHODS: 20 nickel allergic individuals were tested...... compared to the small area. It was also found that the ROAT threshold (per application) was lower than the patch test threshold. CONCLUSION: For elicitation of nickel allergy, the size of the exposed area and therefore the total amount of applied nickel, influence the elicitation reaction at some...

  14. Per-energy capacity and handoff strategies in macro-femto cells environment

    KAUST Repository

    Leon, Jaime

    2012-04-01

    The effect of smaller cells being placed in a heterogenous network can improve the way energy is spent in a system. Handoff strategies, bandwidth allocation and path loss calculations in different scenarios show how this is possible as the size of the cell is decreased. As a result, users can experience the same or better capacities while maximising the capacity per unit energy spent. The per-energy capacity metric is introduced as a suitable handoff strategy that considers the energy spent as an important criterion. © 2012 IEEE.

  15. Los últimos años del período amarniense

    Directory of Open Access Journals (Sweden)

    Antonio Pérez Largacha

    1994-01-01

    Full Text Available Referirse al período amarniense, en cualquiera de sus manifestaciones y etapas, implica adentrarse en una polémica constante, con opiniones y teorías contrapuestas en las que tienen no poca incidencia el grado de simpatía o reciíazo que la figura de Akhenatón despierta. El mejor ejemplo de ello son las opiniones antagónicas de dos de los principales especialistas del período, Redford (1984 y Alfred (1988, perfectamente contrapuestas por Eaton-Krauss en su «Akhenaten versus Akhenaten» (1990.

  16. Tires de paper per avaluar la toxicitat de l'aigua

    OpenAIRE

    Pujol, Feran Departament de Genètica i Microbiologia

    2016-01-01

    Les tècniques d'anàlisis químiques utilitzades per analitzar mostres d'aigua que poden contenir diversos contaminants tenen certes limitacions. Investigadors del grup de Microbiologia Ambiental del Departament de Genètica i Microbiologia de la UAB han desenvolupat una tècnica senzilla i de baix cost per a la detecció de toxicitat en aigua. Aquesta consisteix en monitoritzar el canvi de color de matrius de paper que contenen bacteris i un colorant que canvia de color quant és respirat pels mic...

  17. Perspectivas a largo plazo de la acuicultura en el Perú.

    OpenAIRE

    Salázar, Raúl

    1989-01-01

    Este documento presenta una visión general de la situación y perspectivas de la acuicultura en el Perú, con énfasis en el aspecto económico. Analiza la situación actual de la acuicultura a escala mundial y sus perspectivas a largo plazo, y evalúa el potencial acuícola del país, encontrándose que en el ámbito marino el Perú dispone de ventajas en relación a otros países. Por último, evalúa la experiencia peruana en diversos tipos de acuicultura.

  18. Cestodos de quirópteros del Parque Nacional Cerros de Amotape, Tumbes, Perú

    Directory of Open Access Journals (Sweden)

    Marina Vargas

    2011-07-01

    Full Text Available En septiembre 2006, en el Parque Nacional Cerros de Amotape, departamento de Tumbes, Perú; 39 individuos de murciélagos, pertenecientes a 16 especies fueron capturados. El análisis parasitológico determino que solo dos individuos de las especies Phyllostomus hastatus (Phyllostomidae y Noctilio leporinus (Noctilionidae estaban parasitados. Los cestodos fueron colectados del intestino delgado e identificados como Atriotaenia hastati Vaucher, 1982 (Anoplocephalidae y Vampirolepis sp. (Hymenolepididae. Atriotaenia hastati es un nuevo registro para el Perú y Vampirolepis sp. es registrado por primera vez en Tumbes y en un nuevo huésped, Noctilio leporinus.

  19. Necessitats educatives per promoure la salut afectiva i sexual en joves en risc social

    OpenAIRE

    M.Àngels Balsells; Ma. Cruz Molina Garuz; Núria Fuentes-Peláez; Crescencia Pastor-Vicente; Pere Amorós-Martí

    2014-01-01

    L’educació afectiva y sexual dels i les joves en situació de risc social és un element essencial per a la seva salut. L’educació en aquesta àrea requereix uns plantejaments rigorosos que es basin en les necessitats educatives i diferencials d’aquest col·lectiu en relació a la salut afectiva i sexual. Aquest article presenta els resultats d’una investigació que analitza aquestes necessitats. Per a això, es va dissenyar una investigació acció participativa de caràcter qualitativa, en la qual va...

  20. Una teràpia per a la bulímia

    OpenAIRE

    Fernández-Aranda, Fernando

    2012-01-01

    Un estudi realitzat per un equip de l'Hospital Universitari de Bellvitge, dirigit pel Dr. Fernando Fernández-Aranda i analitzat per les professores Roser Granero i Eva Penelo del Departament de Psicobiologia i de Metodologia de la Ciències de la Salut de la UAB, ha aprofundit en com la teràpia cognitiva-conductual en pacients que pateixen un trastorn de la conducta alimentària permet reduir els símptomes depressius de les afectades. El treball mostra com aquest tipus de tractament, amb una ac...