WorldWideScience

Sample records for ten key issues

  1. Ten Keys to the Portal

    Science.gov (United States)

    Schaffhauser, Dian

    2011-01-01

    Successful web portals help users stay informed, in touch, and up to speed. They are also a telling window into the efficiency of one's institution. To develop a cutting-edge portal takes planning, communication, and research. In this article, the author presents and discusses 10 keys to portal success: (1) make critical info visible; (2) make the…

  2. Top-Ten IT Issues, 2008

    Science.gov (United States)

    Allison, Debra H.; DeBlois, Peter B.

    2008-01-01

    EDUCAUSE presents the top-ten IT-related issues in terms of strategic importance to the higher education institution, as revealed by the ninth annual EDUCAUSE Current Issues Survey. This year, "Security" moves back to the top of the list. (Contains 20 notes.)

  3. Low carbon development. Key issues

    Energy Technology Data Exchange (ETDEWEB)

    Urban, Frauke; Nordensvaard, Johan (eds.)

    2013-03-07

    This comprehensive textbook addresses the interface between international development and climate change in a carbon constrained world. It discusses the key conceptual, empirical and policy-related issues of low carbon development and takes an international and interdisciplinary approach to the subject by drawing on insights from across the natural sciences and social sciences whilst embedding the discussion in a global context. The first part explores the concept of low carbon development and explains the need for low carbon development in a carbon constrained world. The book then discusses the key issues of socio-economic, political and technological nature for low carbon development, exploring topics such as the political economy, social justice, financing and carbon markets, and technologies and innovation for low carbon development. This is followed by key issues for low carbon development in policy and practice, which is presented based on cross-cutting issues such as low carbon energy, forestry, agriculture and transportation. Afterwards, practical case studies are discussed from low carbon development in low income countries in Africa, middle income countries in Asia and Latin America and high income countries in Europe and North America.

  4. TEN KEY CONCEPTS AND THE SUCCESS OF ROMANIAN ORGANIZATIONS

    Directory of Open Access Journals (Sweden)

    Ada Mirela TOMESCU

    2006-01-01

    Full Text Available This paper is focused on ten key concepts which influence the success of theorganizations at the beginning of XXI century. The great changes generatedby globalization determine firms to be more competitive. This means that wehave to focus on: mission, leadership, emotional intelligence, innovation,organizational culture, human resources, total quality management, ethics,conflict management, brand, and the value offered to the clients.

  5. Key issues in transplant tourism.

    Science.gov (United States)

    Akoh, Jacob A

    2012-02-24

    Access to organ transplantation depends on national circumstances, and is partly determined by the cost of health care, availability of transplant services, the level of technical capacity and the availability of organs. Commercial transplantation is estimated to account for 5%-10% (3500-7000) of kidney transplants performed annually throughout the world. This review is to determine the state and outcome of renal transplantation associated with transplant tourism (TT) and the key challenges with such transplantation. The stakeholders of commercial transplantation include: patients on the waiting lists in developed countries or not on any list in developing countries; dialysis funding bodies; middlemen, hosting transplant centres; organ-exporting countries; and organ vendors. TT and commercial kidney transplants are associated with a high incidence of surgical complications, acute rejection and invasive infection which cause major morbidity and mortality. There are ethical and medical concerns regarding the management of recipients of organs from vendors. The growing demand for transplantation, the perceived failure of altruistic donation in providing enough organs has led to calls for a legalised market in organ procurement or regulated trial in incentives for donation. Developing transplant services worldwide has many benefits - improving results of transplantation as they would be performed legally, increasing the donor pool and making TT unnecessary. Meanwhile there is a need to re-examine intrinsic attitudes to TT bearing in mind the cultural and economic realities of globalisation. Perhaps the World Health Organization in conjunction with The Transplantation Society would set up a working party of stakeholders to study this matter in greater detail and make recommendations.

  6. Environmental conflicts: Key issues and management implications ...

    African Journals Online (AJOL)

    Environmental conflicts have emerged as key issues challenging local, regional, national and global security. Environmental crises and problems throughout the world are widespread and increasing rapidly. In relation to these concerns, the article discusses the following aspects: people and the environment, environmental ...

  7. Keys to success: Ten case studies of effective weatherization programs

    Energy Technology Data Exchange (ETDEWEB)

    Brown, M.A.; Berry, L.G.; Kolb, J.O.; White, D.L. [Oak Ridge National Lab., TN (United States); Kinney, L.F.; Wilson, T. [Synertech Systems Corp., Syracuse, NY (United States)

    1993-11-01

    In 1990, DOE initiated a nationwide evaluation of its Weatherization Program, with assistance from Oak Ridge National Laboratory and an advisory group of 40 weatherization professionals, program managers, and researchers. The evaluation is comprised of three impact studies covering the Program`s major market segments: Single-family homes, mobile homes, and dwellings in small (2 to 4-unit) multifamily buildings (the Single-Family Study), Single-family homes heated primarily with fuel oil (the Fuel-Oil Study), and Dwellings in buildings with five or more units (the Multifamily Study). The Single-Family Study, the subject of this report, is a critical part of this coordinated evaluation effort. Its focus on single-family dwellings, mobile homes, and dwellings in small multifamily buildings covers 83% of the income-eligible population and 96% of the dwellings weatherized during Program Year 1989. The first phase of the Single-Family Study involved the analysis of a massive data base of information collected from 368 local weatherization agencies and 543 electric and gas utilities. This analysis resulted in energy-saving and cost-effectiveness estimates for the Weatherization Program and the identification of a set of ten high-performing agencies located throughout the country. The second phase, which is the subject of this report, involves a ``process`` evaluation of these ten high performers, aimed at identifying those weatherization practices that explain their documented success.

  8. Ten key elements for implementing interprofessional learning in ...

    African Journals Online (AJOL)

    This paper discusses 10 key elements for the design and implementation of interprofessional education (IPE) in a skills centre. The elements are based on published literature as well as on the experience of an IPE initiative, simulating the management of a multiple-traumatised patient in the acute and rehabilitation phases, ...

  9. Ten Key Issues in Lexicography for the Future

    DEFF Research Database (Denmark)

    2009-01-01

    and recommendations for theoretical and practical lexicographical work. The gist of the concluding discussion is that lexicography is a general term for a research discipline and a professional activity. Theoretical lexicography has as its objective to develop principles and guidelines that help practitioners...... to produce lexicographical tools that fulfil the needs of specific types of users in specific types of situations in the real world. Furthermore, the theoretical branch of lexicography has to be measured on the basis of the methods used to achieve the objective, and these methods may be purely...

  10. Adding-Listing Machines (Ten-Key and Full-Key), Business Education: 7718.07.

    Science.gov (United States)

    McKinney, Lottie N.

    This pamphlet describes a course designed to give students mastery over the 10-key and full-key adding-listing machines in solving special business problems. With course guidelines, performance objectives, course content, learning activities, evaluative instruments, student and teacher resources, the course content seeks to develop occupational…

  11. Preface: Special issue: ten years of advances in computer entertainment

    NARCIS (Netherlands)

    Katayose, Haruhiro; Rauterberg, M; Reidsma, Dennis

    2014-01-01

    This special issue celebrates the 10th edition of the International Conference on Advances in Computer Entertainment (ACE) by collecting six selected and revised papers from among this year’s accepted contributions.

  12. Key Issues in Global Technological Innovation Projects

    Directory of Open Access Journals (Sweden)

    Roberto Sbragia

    2012-04-01

    Full Text Available This article aimed to identify those issues that were present in global technological innovation projects carried out by Brazilian multinational companies and which performance criterions these undertakings met. We investigated 36 global technological innovation projects from Brazilian multinational enterprises through a web-survey. Findings show that these companies went beyond the traditional iron triangle to evaluate their technological efforts and considered additional performance dimensions such as customer satisfaction, business results, and preparation for the future. Results also show high degree of presence for issues emerging from the industry, moderate degree of presence for issues emerging from both the project and R&D activities, and low degree of presence for issues emerging from the headquarters, the subsidiaries, and the external environment. Further research is needed to find out if and how these issues influenced the performance of the global technological innovation projects studied.DOI:10.5585/gep.v3i1.72

  13. Environmental conflicts: Key issues and management implications ...

    African Journals Online (AJOL)

    African Journal on Conflict Resolution. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 10, No 2 (2010) >. Log in or Register to get access to full text downloads.

  14. Strategies of Educational Decentralization: Key Questions and Core Issues.

    Science.gov (United States)

    Hanson, E. Mark

    1998-01-01

    Explains key issues and forces that shape organization and management strategies of educational decentralization, using examples from Colombia, Venezuela, Argentina, Nicaragua, and Spain. Core decentralization issues include national and regional goals, planning, political stress, resource distribution, infrastructure development, and job…

  15. Key issues in space nuclear power

    Science.gov (United States)

    Brandhorst, Henry W.

    1991-01-01

    The future appears rich in missions that will extend the frontiers of knowledge, human presence in space, and opportunities for profitable commerce. Key to the success of these ventures is the availability of plentiful, cost effective electric power and assured, low cost access to space. While forecasts of space power needs are problematic, an assessment of future needs based on terrestrial experience has been made. These needs fall into three broad categories: survival, self sufficiency, and industrialization. The cost of delivering payloads to orbital locations from LEO to Mars has been determined and future launch cost reductions projected. From these factors, then, projections of the performance necessary for future solar and nuclear space power options has been made. These goals are largely dependent upon orbital location and energy storage needs. Finally the cost of present space power systems has been determined and projections made for future systems.

  16. Key issues for sustainable urban stormwater management.

    Science.gov (United States)

    Barbosa, A E; Fernandes, J N; David, L M

    2012-12-15

    Since ancient times, it is understood that stormwater from constructed areas should be managed somehow. Waste and pollution transported by stormwater poses quantity and quality problems, affecting public health and the quality of the environment. Sanitation infrastructures in urbanized regions have different development levels and the perception of stormwater changed considerably during the centuries and especially in recent years. Still, there is an evident worldwide heterogeneity when analyzing the lack of studies on urban stormwater conducted in some Asian or African countries. Strategies for sustainable stormwater management are needed at different decision levels (political, regional or local scale, for instance) but all of them need information and a clear understanding of the possibilities that are at stake as well as the main consequences of each decision. A sound approach to stormwater management should be flexible, based on local characteristics, and should take into consideration temporal, spatial and administrative factors and law, among other issues. Economic or technical constraints define different decision scenarios. Best Management Practices should be seen as an opportunity for development and improvement of social, educational and environmental conditions in urbanized and surrounding areas. Therefore they require an ample perspective and the participation of different stakeholders. High-quality decision needs time and a fair overview of the problem: the purpose of this document is to contribute to sustainable stormwater management, informing on the most relevant factors that should be assessed and their interaction. A flowchart has been produced and is presented, indicating the most relevant steps, processes and information that should be taken into account in urban development. Copyright © 2012 Elsevier Ltd. All rights reserved.

  17. Information Systems Management: an Australian view of the key issues

    Directory of Open Access Journals (Sweden)

    Graham Pervan

    1994-05-01

    Full Text Available Studies investigating the key issues in IS management serve to better understand the concerns of IS managers and help to guide IS researchers in choosing IS management problems worthy of investigation. This paper presents results from a study of the key issues facing the IS managers of Australia's largest 300 organisations which is part of a three-yearly longitudinal study. In order to gain consensus on the relative importance of the key issues, a three-round Delphi method was applied. The results reveal that IS strategic planning continues to be the paramount issue in our industry, as are many issues associated with IS strategic planning, including responsiveness of the IT infrastructure, effective use of the data resource, IS for competitive advantage, and a comprehensive information architecture. A greater emphasis on quality is also revealed in highly rated issues such as effective use of the data resource, data integrity and quality assurance, and the quality of software development

  18. Teacher-Student Sexual Relations: Key Risks and Ethical Issues

    Science.gov (United States)

    Sikes, Pat

    2010-01-01

    Researching actual or purported sexual contact between teachers and students raises many difficult ethical issues, questions and dilemmas, which may help to explain why few have ventured into the field. This experientially based paper addresses key problem areas under the headings of: the ethics of researching a sensitive taboo topic; the ethics…

  19. Social Work Practice with Latinos: Key Issues for Social Workers

    Science.gov (United States)

    Furman, Rich; Negi, Nalini Junko; Iwamoto, Derek Kenji; Rowan, Diana; Shukraft, Allison; Gragg, Jennifer

    2009-01-01

    The Latino population is the fastest growing group in the United States; thus, it is imperative that social workers and other mental health practitioners be knowledgeable about the current literature on how to effectively serve this population. This article elucidates key issues and knowledge, such as immigration and migration concerns; discusses…

  20. Mixed Methods Research: What Are the Key Issues to Consider?

    Science.gov (United States)

    Ghosh, Rajashi

    Mixed methods research (MMR) is increasingly becoming a popular methodological approach in several fields due to the promise it holds for comprehensive understanding of complex problems being researched. However, researchers interested in MMR often lack reference to a guide that can explain the key issues pertaining to the paradigm wars…

  1. Power quality event classification: an overview and key issues ...

    African Journals Online (AJOL)

    ... used for PQ events' classifications. Various artificial intelligent techniques which are used in PQ event classification are also discussed. Major Key issues and challenges in classifying PQ events are critically examined and outlined. Keywords: Power quality, PQ event classifiers, artificial intelligence techniques, PQ noise, ...

  2. Key management issue in SCADA networks: A review

    Directory of Open Access Journals (Sweden)

    Abdalhossein Rezai

    2017-02-01

    Full Text Available Supervisory Control And Data Acquisition (SCADA networks have a vital role in Critical Infrastructures (CIs such as public transports, power generation systems, gas, water and oil industries, so that there are concerns on security issues in these networks. The utilized Remote Terminal Units (RTUs and Intelligence Electronic Devices (IEDs in these networks have resource limitations, which make security applications a challenging issue. Efficient key management schemes are required besides lightweight ciphers for securing the SCADA communications. Many key management schemes have been developed to address the tradeoff between SCADA constrain and security, but which scheme is the most effective is still debatable. This paper presents a review of the existing key management schemes in SCADA networks, which provides directions for further researches in this field.

  3. Information Systems Management: an Australasian view of key issues - 1996

    Directory of Open Access Journals (Sweden)

    Graham Pervan

    1997-11-01

    Full Text Available As part of a longitudinal study of key information systems management issues, a survey of Australasia's largest 500 organisations was conducted to identify which issues were perceived by the IS executives as being important, problematic and critical over the next three to five years. The most critical issues were revealed to be a mix of technology management issues (IT infrastructure, communications, disaster recovery, strategic management issues (competitive advantage, IS planning, aligning the IS organisation, people management issues (organisational learning, educating senior management in IT, systems development and data management issues (effective use of the data resource, and end-user computing. This reflects the need for a balance of business, technical, and people skills in an IS executive. Non-critical issues were mostly related to systems development and the individual technologies which must be integrated and managed to ensure a responsive IT infrastructure. The study also reveals that some issues are much more important than problematic (disaster recovery, competitive advantage, information architecture, and IS alignment while others are much more problematic than important (end-user computing, IS role and contribution, and BPR. The former reflects a growing level of knowledge in handling these issues, while the latter reflects a continuing problem with them. The differences between this study and similar studies conducted in 1988 and 1992 show that there is a growing confidence in the IS executive's ability to manage the strategic issues, a continuing concern about providing a responsive IT infrastructure (especially communications, and a continuing concern with educating all 'customers' in the organisation in the effective use of IT, including senior management.

  4. Nanotechnologies for Climate Friendly Construction – Key Issues and Challenges

    DEFF Research Database (Denmark)

    Andersen, Maj Munch; Geiker, Mette Rica

    2009-01-01

    Expectations as to the climate potentials of nanotechnology are high, none the least related to the construction sector. This paper seeks to highlight key aspects in the early development and application of eco-innovative nanotech solutions in the construction sector, “nanoconstruction”. The paper...... provides a framework for addressing relevant issues of green nanoconstruction and takes stock of current challenges. Eco-innovative nanoconstruction has the potential to simultaneously enhance the competitiveness and climate potential of the construction sector and could become a key strategic factor...

  5. Key emotional issues for couples of mixed HIV status.

    Science.gov (United States)

    Beckerman, N L; Letteney, S; Lorber, K

    2000-01-01

    With more effective treatment advances, long term HIV survivors are turning their attention back towards career and relationship. Based on a research study (N = 82) this article provides a preliminary overview of the key emotional experiences of being in a primary relationship of mixed HIV status. The article reviews relevant literature on emotional stresses and challenges facing the individual in such a relationship and reports on the study's quantitative and qualitative findings on the subject. Regardless of serostatus, sexual orientation or gender, key issues clearly emerged for this population. They are fearful of HIV transmission, impact of uncertainty, an increase in emotional closeness due to HIV as well as an inevitable emotional distance due to the difference in HIV status. Secondary issues included reproductive dilemmas and struggles given one partner's HIV status and difficulty with disclosing a partner's HIV positive status to others. Implications for social workers in health care are provided.

  6. Wildfire in the United Kingdom: status and key issues

    Science.gov (United States)

    Julia. McMorrow

    2011-01-01

    This paper reviews the status of wildfire risk in the United Kingdom and examines some of the key issues in U.K. wildfire management. Wildfires challenge the resources of U.K. Fire and Rescue Services (FRSs), especially in dry years, yet FRSs are poorly equipped and trained to deal with wildfire. A brief geography of U.K. wildfires is presented using fire statistics...

  7. Key issues and technical route of cyber physical distribution system

    Science.gov (United States)

    Zheng, P. X.; Chen, B.; Zheng, L. J.; Zhang, G. L.; Fan, Y. L.; Pei, T.

    2017-01-01

    Relying on the National High Technology Research and Development Program, this paper introduced the key issues in Cyber Physical Distribution System (CPDS), mainly includes: composite modelling method and interaction mechanism, system planning method, security defence technology, distributed control theory. Then on this basis, the corresponding technical route is proposed, and a more detailed research framework along with main schemes to be adopted is also presented.

  8. Issues in mHealth: findings from key informant interviews.

    Science.gov (United States)

    Whittaker, Robyn

    2012-10-02

    mHealth is enjoying considerable interest and private investment in the United States. A small but growing body of evidence indicates some promise in supporting healthy behavior change and self-management of long-term conditions. The unique benefits mobile phones bring to health initiatives, such as direct access to health information regardless of time or location, may create specific issues for the implementation of such initiatives. Other issues may be shared with general health information technology developments. To determine the important issues facing the implementation of mHealth from the perspective of those within the US health system and those working in mHealth in the United States. Semistructured interviews were conducted with 27 key informants from across the health and mHealth sectors in the United States. Interviewees were approached directly following an environmental scan of mHealth in the United States or recommendation by those working in mHealth. The most common issues were privacy and data security, funding, a lack of good examples of the efficacy and cost effectiveness of mHealth in practice, and the need for more high-quality research. The issues are outlined and categorized according to the environment within which they predominantly occur: policy and regulatory environments; the wireless industry; the health system; existing mHealth practice; and research. Many of these issues could be addressed by making the most of the current US health reform environment, developing a strategic and coordinated approach, and seeking to improve mHealth practice.

  9. Diversity and representation: Key issues for psychophysiological science.

    Science.gov (United States)

    Gatzke-Kopp, Lisa M

    2016-01-01

    This Special Issue is devoted to the illustration and discussion of three key demographic variables (sex/gender, race/ethnicity, and socioeconomic status) that have been shown to moderate associations between psychophysiological processes and behavior. The introduction to the issue discusses the role of phenotypic plasticity in the emergence of different neural processes that achieve the same behavioral outcome, with emphasis on how these relatively stable developmental contexts affect brain/behavior associations without necessarily resulting in difference in behavior. These findings have profound significance for the implications of generalization and call into question the presumption that diverse samples produce an average result that is appropriately reflective of the individuals themselves. Increasing diversity within psychophysiological research is critical in elucidating mechanisms by which the human brain can accomplish cognitive and affective behaviors. This article further examines the logistical and ethical challenges faced in achieving this goal. © 2015 Society for Psychophysiological Research.

  10. Key issues regarding digital libraries evaluation and integration

    CERN Document Server

    Shen, Rao; Fox, Edward A

    2013-01-01

    This is the second book based on the 5S (Societies, Scenarios, Spaces, Structures, Streams) approach to digital libraries (DLs). Leveraging the first volume, on Theoretical Foundations, we focus on the key issues of evaluation and integration. These cross-cutting issues serve as a bridge for those interested in DLs, connecting the introduction and formal discussion in the first book, with the coverage of key technologies in the third book, and of illustrative applications in the fourth book. These two topics have central importance in the DL field, allowing it to be treated scientifically as well as practically. In the scholarly world, we only really understand something if we know how to measure and evaluate it. In the Internet era of distributed information systems, we only can be practical at scale if we integrate across both systems and their associated content. Evaluation of DLs must take place atmultiple levels,so we can address the different entities and their associated measures. Thus, for digital obj...

  11. Human Health Effects of Trichloroethylene: Key Findings and Scientific Issues

    Science.gov (United States)

    Jinot, Jennifer; Scott, Cheryl Siegel; Makris, Susan L.; Cooper, Glinda S.; Dzubow, Rebecca C.; Bale, Ambuja S.; Evans, Marina V.; Guyton, Kathryn Z.; Keshava, Nagalakshmi; Lipscomb, John C.; Barone, Stanley; Fox, John F.; Gwinn, Maureen R.; Schaum, John; Caldwell, Jane C.

    2012-01-01

    Background: In support of the Integrated Risk Information System (IRIS), the U.S. Environmental Protection Agency (EPA) completed a toxicological review of trichloroethylene (TCE) in September 2011, which was the result of an effort spanning > 20 years. Objectives: We summarized the key findings and scientific issues regarding the human health effects of TCE in the U.S. EPA’s toxicological review. Methods: In this assessment we synthesized and characterized thousands of epidemiologic, experimental animal, and mechanistic studies, and addressed several key scientific issues through modeling of TCE toxicokinetics, meta-analyses of epidemiologic studies, and analyses of mechanistic data. Discussion: Toxicokinetic modeling aided in characterizing the toxicological role of the complex metabolism and multiple metabolites of TCE. Meta-analyses of the epidemiologic data strongly supported the conclusions that TCE causes kidney cancer in humans and that TCE may also cause liver cancer and non-Hodgkin lymphoma. Mechanistic analyses support a key role for mutagenicity in TCE-induced kidney carcinogenicity. Recent evidence from studies in both humans and experimental animals point to the involvement of TCE exposure in autoimmune disease and hypersensitivity. Recent avian and in vitro mechanistic studies provided biological plausibility that TCE plays a role in developmental cardiac toxicity, the subject of substantial debate due to mixed results from epidemiologic and rodent studies. Conclusions: TCE is carcinogenic to humans by all routes of exposure and poses a potential human health hazard for noncancer toxicity to the central nervous system, kidney, liver, immune system, male reproductive system, and the developing embryo/fetus. PMID:23249866

  12. Ten Years, Twenty Issues, and Two Hundred Papers of Numeracy: Toward International Reach and Transdisciplinary Utility

    Directory of Open Access Journals (Sweden)

    H.L. Vacher

    2017-07-01

    Full Text Available This issue completes the first ten years of Numeracy. The purpose of this introductory editorial is to review what has happened to the journal in those ten years. In the twenty issues, Numeracy’s output has been 201 papers counting the one or two editorials per issue. More than 50% of the papers are full, peer-reviewed articles, including 13 papers in two theme collections. The others are peer-reviewed notes and perspectives, editor-reviewed book reviews (15% of the total, and a column by contributing co-editor, Dorothy Wallace. The current issue marks an upswing in the number of notes, and our first discussion/reply. The number of papers per year has been increasing (e.g., 66% more in the last three years than in the first three years. The download rate has increased from about 5,000 in the first two years to 5,000 in about 40 days now. The editorial goes on to document two main outcomes. First, the journal is gaining an international reach: more than half the downloads occur outside the United States now, and the number of contributions from outside the United States has increased from 4 in the first five years to 15 in the second five years. Second, the across-the-curriculum nature of quantitative literacy is coming to the fore. The transdisciplinarity of QL is strikingly evident in this issue, which is discussed in some detail, especially how it conforms to the mission of the Association of American Colleges and Universities. The editorial ends with some results from a small ad hoc study of Google Scholar Citation Profiles. The question was, of the profiles that used “numeracy” or “quantitative literacy” as keywords, what other keywords did those profiles use, and what were the source countries? The results show that (1 QL is very much an American term, (2 there is, metaphorically, a vast and interesting numeracy ecosystem out there for Numeracy to engage and serve, and (3 as we become more global, the transdisciplinary relevance

  13. Offshore Wind Power Experiences, Potential and Key Issues for Deployment

    DEFF Research Database (Denmark)

    Lemming, Jørgen Kjærgaard; Morthorst, Poul Erik; Clausen, Niels-Erik

    Wind power has been growing at spectacular rates. Today it is the largest non-hydro renewable power technology. Worldwide there is 74 GW of installed capacity which is 1.7% of power generation capacity and in 2006 it accounted for 0.82% of electricity production. However, offshore wind still only......, machine elements, electrical design and grid integration could drive investment costs from present-day range of 1.9 to 2.2 mill.€/MW down to 1.35 - 1.54 mill.€/MW in 2050, which accounts for a reduction of costs of approx. 35% . In order to sum up progress and identify future research needs...... of the IEA Wind Agreement and governments involved on key wind issues related to offshore technologies....

  14. The Key Issues of Labor Migration in the Czech Republic

    Directory of Open Access Journals (Sweden)

    Marie JELINKOVA

    2007-04-01

    Full Text Available This paper aims to highlight some often occurring failures that need to be eliminated when attempting to develop an integral and efficient policy on labor migration. As an example, a brief overview of the development of immigration policies and its critical shortcomings in the Czech Republic is provided. Following this, the paper analyzes two aspects: the protection of migrant workers and the trafficking in human beings. In particular, the paper deals with three crucial issues of labor migration which are: (1 the inconsistent aims of immigration policies, (2 the client system, and (3 the dependence on middlemen. The paper also focuses on the role of state, police, and NGO’s in the trafficking in human beings and forced labor or labor exploitation in the Czech Republic. In addition, the legislation on forced labor and the possibilities of assistance to trafficked person are analyzed.By comparing various aspects of immigration policy, this paper covers some, but certainly not all, of the key issues concerning the process of immigrant integration. Several suggestions are made that could improve the situation of labor migrants in a significant way.

  15. Menopause and sexuality: key issues in premature menopause and beyond.

    Science.gov (United States)

    Graziottin, Alessandra

    2010-09-01

    Woman's sexuality encompasses sexual identity, sexual function, and sexual relationships. It is modulated throughout life by life and reproduction-related events, health, relationships, and sociocultural variables. The aging process and menopause are two potent contributors to female sexual dysfunction. The earlier the menopause, the more severe and complex the impact on sexuality is. The younger the woman, the less she realizes the different key goals of her life cycle (falling in love, having a satisfying sexual life, forming a stable couple, getting married, having a family) and the more pervasive the consequences on her sexual identity, sexual function, and sexual relationship can be. Premature menopause is an amplified paradigm of the complex impact menopause can have on women's and couple's sexuality. This paper will focus on biologically based sexual issues, namely desire, arousal, orgasm, and pain disorders, as well as key questions encountered in infertility. The concepts of "symptom inducer" and "symptom carrier" will also be addressed. © 2010 New York Academy of Sciences.

  16. Development of Performance Dashboards in Healthcare Sector: Key Practical Issues.

    Science.gov (United States)

    Ghazisaeidi, Marjan; Safdari, Reza; Torabi, Mashallah; Mirzaee, Mahboobeh; Farzi, Jebraeil; Goodini, Azadeh

    2015-10-01

    Static nature of performance reporting systems in health care sector has resulted in inconsistent, incomparable, time consuming, and static performance reports that are not able to transparently reflect a round picture of performance and effectively support healthcare managers' decision makings. So, the healthcare sector needs interactive performance management tools such as performance dashboards to measure, monitor, and manage performance more effectively. The aim of this article was to identify key issues that need to be addressed for developing high-quality performance dashboards in healthcare sector. A literature review was established to search electronic research databases, e-journals collections, and printed journals, books, dissertations, and theses for relevant articles. The search strategy interchangeably used the terms of "dashboard", "performance measurement system", and "executive information system" with the term of "design" combined with operator "AND". Search results (n=250) were adjusted for duplications, screened based on their abstract relevancy and full-text availability (n=147) and then assessed for eligibility (n=40). Eligible articles were included if they had explicitly focused on dashboards, performance measurement systems or executive information systems design. Finally, 28 relevant articles included in the study. Creating high-quality performance dashboards requires addressing both performance measurement and executive information systems design issues. Covering these two fields, identified contents were categorized to four main domains: KPIs development, Data Sources and data generation, Integration of dashboards to source systems, and Information presentation issues. This study implies the main steps to develop dashboards for the purpose of performance management. Performance dashboards developed on performance measurement and executive information systems principles and supported by proper back-end infrastructure will result in

  17. Key design issues for user terminals operating with HEO satellites

    Science.gov (United States)

    Stojkovic, I.; Alonso, J. E.

    1995-01-01

    Coverage of high-latitude areas in the northern hemisphere using geostationary satellites can not be achieved with good elevation angles, and highly inclined elliptical orbits (HEO) present one possible way to overcome this problem. The high elevation angles they achieve and the relative motion of the satellites across the sky, including satellite hand-over, present a specific set of requirements for the design of user terminals, be they for communication or broadcast-reception purposed. This paper reviews key design issues for user terminals operating with satellites in highly inclined elliptical orbits. While all aspects of user terminal design are broadly covered, special emphasis is given to the antenna and RF front-end design. The types of terminals discussed include communications terminals: the hand-held, the notebook, and the vehicle-mounted types, as well as the vehicle-mounted digital audio broadcasting (DAB) receiver terminal. A number of solutions are outlined, based on tradeoffs with respect to the most significant system interface parameters such as G/T and equivalent isotropically radiated power (EIRP). Candidate antenna and front-end configurations were studied, in particular patch and helical antennas with the principal aim of deriving low cost, yet effective solutions. Issues related to achieving best EIRP for the communications terminals are presented, taking into account radiation safety limits. The differences in the design of receive only versus receive/transmit RF front-ends for HEO system terminals are highlighted and solutions for both proposed. This paper summarizes the results of internal ESTEC studies and external ESA-sponsored work concerning major user terminal parameters and design aspects performed for Archimedes -- a HEO satellite constellation for multimedia broadcasting and communications.

  18. Human health effects of dichloromethane: key findings and scientific issues.

    Science.gov (United States)

    Schlosser, Paul M; Bale, Ambuja S; Gibbons, Catherine F; Wilkins, Amina; Cooper, Glinda S

    2015-02-01

    The U.S. EPA's Integrated Risk Information System (IRIS) completed an updated toxicological review of dichloromethane in November 2011. In this commentary we summarize key results and issues of this review, including exposure sources, identification of potential health effects, and updated physiologically based pharmacokinetic (PBPK) modeling. We performed a comprehensive review of primary research studies and evaluation of PBPK models. Hepatotoxicity was observed in oral and inhalation exposure studies in several studies in animals; neurological effects were also identified as a potential area of concern. Dichloromethane was classified as likely to be carcinogenic in humans based primarily on evidence of carcinogenicity at two sites (liver and lung) in male and female B6C3F1 mice (inhalation exposure) and at one site (liver) in male B6C3F1 mice (drinking-water exposure). Recent epidemiologic studies of dichloromethane (seven studies of hematopoietic cancers published since 2000) provide additional data raising concerns about associations with non-Hodgkin lymphoma and multiple myeloma. Although there are gaps in the database for dichloromethane genotoxicity (i.e., DNA adduct formation and gene mutations in target tissues in vivo), the positive DNA damage assays correlated with tissue and/or species availability of functional glutathione S-transferase (GST) metabolic activity, the key activation pathway for dichloromethane-induced cancer. Innovations in the IRIS assessment include estimation of cancer risk specifically for a presumed sensitive genotype (GST-theta-1+/+), and PBPK modeling accounting for human physiological distributions based on the expected distribution for all individuals 6 months to 80 years of age. The 2011 IRIS assessment of dichloromethane provides insights into the toxicity of a commonly used solvent.

  19. Key issues in the design of pay for performance programs.

    Science.gov (United States)

    Eijkenaar, Frank

    2013-02-01

    Pay for performance (P4P) is increasingly being used to stimulate healthcare providers to improve their performance. However, evidence on P4P effectiveness remains inconclusive. Flaws in program design may have contributed to this limited success. Based on a synthesis of relevant theoretical and empirical literature, this paper discusses key issues in P4P-program design. The analysis reveals that designing a fair and effective program is a complex undertaking. The following tentative conclusions are made: (1) performance is ideally defined broadly, provided that the set of measures remains comprehensible, (2) concerns that P4P encourages "selection" and "teaching to the test" should not be dismissed, (3) sophisticated risk adjustment is important, especially in outcome and resource use measures, (4) involving providers in program design is vital, (5) on balance, group incentives are preferred over individual incentives, (6) whether to use rewards or penalties is context-dependent, (7) payouts should be frequent and low-powered, (8) absolute targets are generally preferred over relative targets, (9) multiple targets are preferred over single targets, and (10) P4P should be a permanent component of provider compensation and is ideally "decoupled" form base payments. However, the design of P4P programs should be tailored to the specific setting of implementation, and empirical research is needed to confirm the conclusions.

  20. Key issues review: evolution on rugged adaptive landscapes

    Science.gov (United States)

    Obolski, Uri; Ram, Yoav; Hadany, Lilach

    2018-01-01

    Adaptive landscapes represent a mapping between genotype and fitness. Rugged adaptive landscapes contain two or more adaptive peaks: allele combinations with higher fitness than any of their neighbors in the genetic space. How do populations evolve on such rugged landscapes? Evolutionary biologists have struggled with this question since it was first introduced in the 1930s by Sewall Wright. Discoveries in the fields of genetics and biochemistry inspired various mathematical models of adaptive landscapes. The development of landscape models led to numerous theoretical studies analyzing evolution on rugged landscapes under different biological conditions. The large body of theoretical work suggests that adaptive landscapes are major determinants of the progress and outcome of evolutionary processes. Recent technological advances in molecular biology and microbiology allow experimenters to measure adaptive values of large sets of allele combinations and construct empirical adaptive landscapes for the first time. Such empirical landscapes have already been generated in bacteria, yeast, viruses, and fungi, and are contributing to new insights about evolution on adaptive landscapes. In this Key Issues Review we will: (i) introduce the concept of adaptive landscapes; (ii) review the major theoretical studies of evolution on rugged landscapes; (iii) review some of the recently obtained empirical adaptive landscapes; (iv) discuss recent mathematical and statistical analyses motivated by empirical adaptive landscapes, as well as provide the reader with instructions and source code to implement simulations of evolution on adaptive landscapes; and (v) discuss possible future directions for this exciting field.

  1. Club convergence of house prices: Evidence from China’s ten key cities

    Science.gov (United States)

    Meng, Hao; Xie, Wen-Jie; Zhou, Wei-Xing

    2015-09-01

    The latest global financial tsunami and its follow-up global economic recession has uncovered the crucial impact of housing markets on financial and economic systems. The Chinese stock market experienced a marked fall during the global financial tsunami and China’s economy has also slowed down by about 2%-3% when measured in GDP. Nevertheless, the housing markets in diverse Chinese cities seemed to continue the almost nonstop mania for more than 10 years. However, the structure and dynamics of the Chinese housing market are less studied. Here, we perform an extensive study of the Chinese housing market by analyzing 10 representative key cities based on both linear and nonlinear econophysical and econometric methods. We identify a common collective driving force which accounts for 96.5% of the house price growth, indicating very high systemic risk in the Chinese housing market. The 10 key cities can be categorized into clubs and the house prices of the cities in the same club exhibit an evident convergence. These findings from different methods are basically consistent with each other. The identified city clubs are also consistent with the conventional classification of city tiers. The house prices of the first-tier cities grow the fastest and those of the third- and fourth-tier cities rise the slowest, which illustrates the possible presence of a ripple effect in the diffusion of house prices among different cities.

  2. Offshore wind power experiences, potential and key issues for deployment

    Energy Technology Data Exchange (ETDEWEB)

    Lemming, J.; Morthorst, P.E.; Clausen, Niels-Erik

    2009-01-15

    Wind power has been growing at spectacular rates. Today it is the largest non-hydro renewable power technology. Worldwide there is 74 GW of installed capacity which is 1.7% of power generation capacity and in 2006 it accounted for 0.82% of electricity production. However, offshore wind still only counts for a very small amount and development has only taken place in North European counties round the North Sea and the Baltic Sea over the last 15 years. Offshore wind is still some 50% more expensive than onshore wind, but more wind resources and lesser visual impacts from larger turbines are expected to compensate for the higher installation costs in the long term. Most offshore wind farms are installed in British, Swedish and Danish waters, and present-day costs of installing wind energy in the UK are between 1,200 to 1,600 GBP/kW (1,781 to 2,375 Euro/kW) offshore, while in Sweden investment costs were 1,800 Euro/kW, and in Denmark 1,200 to 1,700 Euro/kW, though investment costs for a new wind farm are expected be in the range of 2.0 to 2.2 mill. Euro/MW for a near-shore shallow depth facility. Future developments in offshore wind technology concerning aerodynamics, structural dynamics, structural design, machine elements, electrical design and grid integration could drive investment costs from present-day range of 1.9 to 2.2 mill. Euro/MW down to 1.35 - 1.54 mill.Euro/MW in 2050, which accounts for a reduction of costs of approx. 35%. In order to sum up progress and identify future research needs, the International Energy Agency (IEA) Wind agreement Task 11 should arrange a new meeting concerning long term research needs for reviewing 'the long term strategy for 2000 to 2020' from 2001, to come up with suggestions / recommendations on how to define and proceed with, the necessary research activities of the IEA Wind Agreement and governments involved on key wind issues related to offshore technologies. (au)

  3. Ten Key Steps to Developing a Programme of University Mentoring for Newly Enrolled Students

    Directory of Open Access Journals (Sweden)

    Raquel Casado-Muñoz

    2015-05-01

    Full Text Available Peer mentoring or tutoring is an educational guidance method that is growing in universities around the world. Directed at the integration of students over the first year of university studies, it is based on the support and guidance that a more experienced student offers to a recently enrolled fellow student. It is a recent process in Spain which started a little over a decade ago, but each course brings more experiences. This article, derived from research, seeks to identify a series of key steps and ideas to implement this type of programme. The summary of the proposals stems from three main sources: a the experience and assessment of the Mentoring Programme at the University of Burgos; b the review of the peer mentoring programs implemented at 35 Spanish universities; and c the review, comparison and adaptation of formal mentoring to the university according to Perrone (2003.  The outcomes may be especially useful for those universities that wish to start mentoring programmes, and as a source of reflection and comparison for those with greater experience. We believe that special attention should be given on increasing and improving participation in the mentoring of newly enrolled students and on monitoring and assessing the whole process.

  4. Key Issues in the Application of Knowledge Management in Education

    National Research Council Canada - National Science Library

    Mendoza, George A

    2005-01-01

    .... This shift in paradigms has made knowledge the key resource as organizations shift their focus from natural resources to intellectual assets, heralding the use of a concept called Knowledge Management (KM...

  5. Menopause and sexuality: key issues in premature menopause and beyond

    National Research Council Canada - National Science Library

    Graziottin, Alessandra

    2010-01-01

    ... is. The younger the woman, the less she realizes the different key goals of her life cycle (falling in love, having a satisfying sexual life, forming a stable couple, getting married, having a family...

  6. A constructionist view on language innovation. Some key issues

    OpenAIRE

    Van Goethem, Kristel; Research Seminar of the Modern Greek Dialect Research Laboratory

    2015-01-01

    This presentation provides an introduction into Construction Grammar and Construction Morphology. In the second part the constructionist framework is applied to the case study of the debonding of compound-like sequences with French clé 'key'.

  7. Liberia's Post-War Recovery: Key Issues and Developments

    National Research Council Canada - National Science Library

    Cook, Nicolas

    2006-01-01

    .... It held elections in October 2005, with a presidential run-off vote in November -- a key step in a post-conflict transition and peace-building process that began following its second civil war in a decade...

  8. Key issues to consider in microalgae based biodiesel production

    DEFF Research Database (Denmark)

    Singh, Anoop; Pant, Deepak; Olsen, Stig Irving

    2012-01-01

    . However, in order to realize this, a complete analysis of full life cycle impact of algal biofuel production in the context of issues such as water resource management, land use impact, energy balance and air emissions are very necessary. The commercial-scale production of algae requires careful...

  9. Key Issue: Teacher Hiring, Placement, and Assignment Practices

    Science.gov (United States)

    Behrstock, Ellen; Coggshall, Jane G.

    2009-01-01

    The literature on teacher hiring and assignment tends to omit definitions of these key terms. An exception in Cohen-Vogel and Osborne-Lampkin (277), who define teacher assignment as "the reciprocal process between school management and teachers to guide decisions about who will teach, where they will teach, and what they will teach." But the…

  10. Implications of Key Performance Indicator Issues in Ontario Universities Explored

    Science.gov (United States)

    Chan, Vivian

    2015-01-01

    Since 1998, the Ministry of Training, Colleges and Universities in Ontario, Canada, has required that data on specific key performance indicators (KPIs) be made public by its publicly funded universities. The information is intended to be used by universities to demonstrate their achievements, to improve their programmes and services, and to…

  11. Key ITER plasma edge and plasma-material interaction issues

    Energy Technology Data Exchange (ETDEWEB)

    Federici, G. E-mail: federig@ipp.mpg.de; Andrew, P.; Barabaschi, P.; Brooks, J.; Doerner, R.; Geier, A.; Herrmann, A.; Janeschitz, G.; Krieger, K.; Kukushkin, A.; Loarte, A.; Neu, R.; Saibene, G.; Shimada, M.; Strohmayer, G.; Sugihara, M

    2003-03-01

    Some of the remaining crucial plasma edge physics and plasma-material interaction issues of the ITER tokamak are discussed in this paper, using either modelling or projections of experimental results from existing tokamak operation or relevant laboratory simulations. The paper covers the following subject areas at issue in the design of the ITER device: (1) plasma thermal loads during Type I ELMs and disruptions, ensuing erosion effects and prospects for mitigating measures, (2) control of co-deposited tritium inventory when carbon is used even on small areas in the divertor near the strike points, (3) efficiency of edge and core fuelling for expected pedestal densities in ITER, and (4) erosion and impurity transport with a full tungsten divertor. Directions and priorities of future research are proposed to narrow remaining uncertainties in the above areas.

  12. Book Review of Education and Technology: Key Issues and Debates

    Directory of Open Access Journals (Sweden)

    Noridah Abu Bakar

    2017-06-01

    Full Text Available The book is written by Neil Selwyn, a Professor from the Faculty of Education in Monash University, Australia to probe our mind regarding issues of technology use in education that seems like inconsistent and often results in unintended consequences and subtle side-effects. The author makes an effort to highlight the problematic as well as the positive aspects of education and technology where most technology development is driven by ambitions to improve and innovate.

  13. Ten Years of bored tunnels in the Netherlands : Part I: Geotechnical issues

    NARCIS (Netherlands)

    Bakker, K.J.; Bezuijen, A.

    2008-01-01

    Ten years have passed since in 1997 for the first time construction of bored tunnels in the Netherlands soft soil was undertaken. Before that date essentially only immersed tunnels and cut-and-cover tunnels were constructed in the Netherlands. The first two bored tunnels were Pilot Projects, the 2nd

  14. Gender equality and sustainable human development are key issues.

    Science.gov (United States)

    Ando, H

    1995-01-01

    In a message to the Indochina Women's Parliamentarians Meeting, Hirofumi Ando, Deputy Executive Director of the United Nations Family Planning Association (UNFPA), encouraged participants to link gender equality and development issues. Ando noted that many of the goals of the 1994 International Conference on Population and Development imply recognition of the need to redress gender inequalities and empower women. The Program of Action adopted in Cairo requires countries to achieve universal access to primary education and reproductive health care services. Parliamentarians in attendance were urged to mobilize the financial resources and political will necessary to implement programs in these areas.

  15. Key issues for low-cost FGD installations

    Energy Technology Data Exchange (ETDEWEB)

    DePriest, W.; Mazurek, J.M. [Sargent & Lundy LLC, Chicago, IL (United States)

    1995-12-01

    This paper will discuss various methods for installing low-cost FGD systems. The paper will include a discussion of various types of FGD systems available, both wet and dry, and will compare the relative cost of each type. Important design issues, such as use of spare equipment, materials of construction, etc. will be presented. An overview of various low-cost construction techniques (i.e., modularization) will be included. This paper will draw heavily from Sargent & Lundy`s database of past and current FGD projects together with information we gathered for several Electric Power Research Institute (EPRI) studies on the subject.

  16. Some key issues in the development of ergonomic intervention tools

    DEFF Research Database (Denmark)

    Edwards, Kasper; Winkel, Jørgen

    2016-01-01

    Literature reviews suggest that tools facilitating the ergonomic intervention processes should be integrated into rationalization tools, particular if such tools are participative. Such a Tool has recently been developed as an add-in module to the Lean tool “Value Stream Mapping” (VSM). However......, in the investigated context this module seems not to have any direct impact on the generation of proposals with ergonomic consideration. Contextual factors of importance seem to be e.g. allocation of sufficient resources and if work environment issues are generally accepted as part of the VSM methodology...

  17. Body Dysmorphic Disorder: Some Key Issues for DSM-V

    Science.gov (United States)

    Phillips, Katharine A.; Wilhelm, Sabine; Koran, Lorrin M.; Didie, Elizabeth R.; Fallon, Brian A.; Feusner, Jamie; Stein, Dan J.

    2014-01-01

    Body dysmorphic disorder (BDD), a distressing or impairing preoccupation with an imagined or slight defect in appearance, has been described for more than a century and increasingly studied over the past several decades. This paper provides a focused review of issues pertaining to BDD that are relevant to DSM-V. The review presents a number of options and preliminary recommendations to be considered for DSM-V: 1) Criterion A may benefit from some rewording, without changing its focus or meaning; 2) Potential disadvantages of adding a new criterion to reflect BDD compulsive behaviors seem to outweigh potential advantages, but adding such a criterion remains an option that can be considered; 3) A clinical significance criterion seems necessary for BDD to differentiate it from normal appearance concerns; 4) BDD and eating disorders have some overlapping features and need to be differentiated; some minor changes to DSM-IV’s criterion C are suggested; 5) BDD should not be broadened to include body integrity identity disorder (apotemnophilia) or olfactory reference syndrome; 6) There is no compelling evidence for including diagnostic features or subtypes that are specific to gender-related, age-related, or cultural manifestations of BDD; 7) Adding muscle dysmorphia as a specifier may have clinical utility; and 8) The ICD-10 criteria for hypochondriacal disorder are not suitable for BDD, and there is no empirical evidence that BDD and hypochondriasis are the same disorder. The issue of how BDD’s delusional variant should be classified in DSM-V is briefly discussed and will be addressed more extensively in a separate paper. PMID:20533368

  18. Body dysmorphic disorder: some key issues for DSM-V.

    Science.gov (United States)

    Phillips, Katharine A; Wilhelm, Sabine; Koran, Lorrin M; Didie, Elizabeth R; Fallon, Brian A; Feusner, Jamie; Stein, Dan J

    2010-06-01

    Body dysmorphic disorder (BDD), a distressing or impairing preoccupation with an imagined or slight defect in appearance, has been described for more than a century and increasingly studied over the past several decades. This article provides a focused review of issues pertaining to BDD that are relevant to DSM-V. The review presents a number of options and preliminary recommendations to be considered for DSM-V: (1) Criterion A may benefit from some rewording, without changing its focus or meaning; (2) There are both advantages and disadvantages to adding a new criterion to reflect compulsive BDD behaviors; this possible addition requires further consideration; (3) A clinical significance criterion seems necessary for BDD to differentiate it from normal appearance concerns; (4) BDD and eating disorders have some overlapping features and need to be differentiated; some minor changes to DSM-IV's criterion C are suggested; (5) BDD should not be broadened to include body integrity identity disorder (apotemnophilia) or olfactory reference syndrome; (6) There is no compelling evidence for including diagnostic features or subtypes that are specific to gender-related, age-related, or cultural manifestations of BDD; (7) Adding muscle dysmorphia as a specifier may have clinical utility; and (8) The ICD-10 criteria for hypochondriacal disorder are not suitable for BDD, and there is no empirical evidence that BDD and hypochondriasis are the same disorder. The issue of how BDD's delusional variant should be classified in DSM-V is briefly discussed and will be addressed more extensively in a separate article. (c) 2010 Wiley-Liss, Inc.

  19. Distributed Generation in Power Systems: An Overview and Key Issues

    DEFF Research Database (Denmark)

    Singh, Sri Niwas

    2009-01-01

    The necessity for smart electrical systems having minimum technical loss and environmental impact is providing impetus to go for Distributed Generations (DGs) which may offer several other advantages such as reduced transmission and distribution system resources, increased reliability, better power...... quality, etc. However, depending on the system configuration and management, these advantages may not be true. Moreover, due to structural and managerial changes in the electricity supply industry motivated with introduction of completion, the role of small generations distributed in the low....../medium voltage network has gained importance. This paper adopts a systematic approach by focusing on the most important research areas related to the distributed generations. Various DG technologies are described and penetration of DGs in the Indian system has been discussed. This paper also highlights the key...

  20. Competence development: Key issues and trends in European competence policies

    DEFF Research Database (Denmark)

    Milana, Marcella

    papers, reports, and communications that led to directives and resolutions concerning the development and recognition of skills and competences in a lifelong learning perspective. In 2005 this process led to the definition of a European Framework on Key Competences for Lifelong Learning - covering those......  In recent years there has been a rising political attention on competence development both at national and international level. At European level in particular, since 2000, with the set of the Lisbon Agenda, different bodies representing the Union have been very productive in generating working...... competences that are given priority within the Union - as well as a European Qualification Framework, a reference tool for making qualifications - here described in terms of progressive levels of competence - transparent and transferable within the European borders. The aim of the paper is to investigate...

  1. Key issues in space nuclear power challenges for the future

    Science.gov (United States)

    Brandhorst, Henry W., Jr.

    1991-01-01

    The future appears rich in missions that will extend the frontiers of knowledge, human presence in space, and opportunities for profitable commerce. Key to the success of these ventures is the availability of plentiful, cost effective electric power and assured, low cost access to space. While forecasts of space power needs are problematic, an assessment of future needs based on terrestrial experience has been made. These needs fall into three broad categories: survival, self sufficiency, and industrialization. The cost of delivering payloads to orbital locations from LEO to Mars has been determined and future launch cost reductions projected. From these factors, then, projections of the performance necessary for future solar and nuclear space power options has been made. These goals are largely dependent upon orbital location and energy storage needs. Finally the cost of present space power systems has been determined and projections made for future systems.

  2. Ten key points for the appropriate use of antibiotics in hospitalised patients: a consensus from the Antimicrobial Stewardship and Resistance Working Groups of the International Society of Chemotherapy

    NARCIS (Netherlands)

    Hara, G. Levy; Kanj, S.S.; Pagani, L.; Abbo, L.; Endimiani, A.; Wertheim, H.F.L.; Amabile-Cuevas, C.; Tattevin, P.; Mehtar, S.; Cardoso, F.; Unal, S.; Gould, I.

    2016-01-01

    The Antibiotic Stewardship and Resistance Working Groups of the International Society for Chemotherapy propose ten key points for the appropriate use of antibiotics in hospital settings. (i) Get appropriate microbiological samples before antibiotic administration and carefully interpret the results:

  3. Reliability, availability, and maintainability: a key issue for ELTs

    Science.gov (United States)

    Ansorge, Wolfgang R.

    2006-06-01

    Hundreds of mirror segment, thousands of high precision actuators, highly complex mechanical, hydraulic, electrical and other technology subsystems, and extremely sophisticated control systems: an ELT system consists of millions of individual parts and components each of them may fail and lead to a partial or complete system breakdown. Component and system reliability does not only influence the acquisition costs of a product, it also defines the necessary maintenance work and the required logistic support. Taking the long operational life time of an ELT into account, reliability and maintainability are some of the main contributors to the system life cycle costs. Reliability and maintainability are key characteristics of any product and have to be designed into it from the early beginning; they can neither be tested into a product nor introduced by numerous maintenance activities. This presentation explains the interconnections between Reliability, Availability, Maintainability and Safety (RAMS) and outlines the necessary RAMS and Reliability Centered Maintenance (RCM) processes and activities during the entire life cycle of an ELT and an ELT instrument from the initial planning to the eventual disposal phase.

  4. Public engagement with CCS: barriers, key issues and ways forward

    Science.gov (United States)

    Xenias, Dimitrios

    2017-04-01

    Although Carbon Capture and Storage (CCS) is recognised as a crucial transition technology to a low-carbon world, it has not been popular with the public or some governments (e.g. the UK). Also, despite its use in industrial processes for decades, CCS remains and unfamiliar technology for most publics. It is therefore important to foster top-down and bottom-up acceptance of large scale CCS. In an exploratory round of interviews we canvassed the views of British, Dutch, German and Norwegian experts (N=13) with previous experience in public engagement with CCS. They identified barriers and drivers for CCS deployment and public engagement with CCS. Thematic analysis revealed a small number of recurrent issues, including: (a) lack of political leadership on CCS; (b) lack of public knowledge on relevant technologies and (c) difficulty communicating why CCS is necessary. Emphasis on these barriers varied with the level of experts' engagement with the public. More interestingly, although most experts agreed on the importance of public engagement, their views divided between 'why' engage and 'how' best to do this. In a subsequent expert survey (N=99) interview findings were reinforced: public support was seen as important for CCS roll-out (72%), though lower than political support and funding. The survey also showed that local public was expected to experience most risks, while global public will experience most benefits; whereas local business is seen to benefit more than global. Experts were overwhelmingly positive about CCS - risks outweigh benefits, and are confident that CCS will play a major role in climate change mitigation (along with reduced energy demand and renewables). These findings will be expanded on and triangulated in a follow-up public survey which will benefit those involved with public engagement with CCS.

  5. Folic acid and human reproduction—ten important issues for clinicians

    Science.gov (United States)

    Dunlap, Beth; Shelke, Kantha; Salem, Shala A.; Keith, Louis G.

    2011-01-01

    This article presents data on the current best evidence-based clinical practices and controversies surrounding folic acid supplementation/fortification for the prevention of neural tube defects (NTDs) during early pregnancy. Formatted as a series of ten clinical questions, answers and extensive discussion are provided for each point. We assess the history and evidence behind supplementation and fortification, racial/ethnic disparities in NTDs on a global scale, and present information on risk factors for NTDs other than dietary folic acid deficiency. Also discussed are public health challenges, including disparities in NTD rates, population-wide monitoring of NTDs, and tracking safety data in the post-fortification era. Emerging data are also reviewed regarding the role folic acid may play in malignant processes, cardiovascular disease, male fertility, and other medical conditions. PMID:21991291

  6. The Presence of Amorpha-4, 11-Diene Synthase, a Key Enzyme in Artemisinin Production in Ten Artemisia Species

    Directory of Open Access Journals (Sweden)

    GA. Garoosi

    2011-12-01

    Full Text Available Background and the purpose of the study: Artemisinin is one of the most effective medicine against malaria, which is produced naturally by Artemisia annua in low yield. It is produced in a metabolic pathway, in which several genes and gene products are involved. One of the key genes in this pathway is am1, which encodes amorpha-4, 11-diene synthase (ADS, a key enzyme in artemisinin biosynthesis pathway. The aim of this study was to determine the presence of this gene in ten Artemisia species in order to increase the yield of production of Artemisinin. Methods : The experiments were carried out using PCR. Specific primers were designed based on the published am1 gene sequence obtained from A. annua (NCBI, accession number AF327527. Results: The amplification of this gene by the specific primers was considered as a positive sign for the potentiality of artemisinin production. Since the entire am1 gene was not amplified in any of the 10 species used, four parts of the gene, essential in ADS enzyme function, corresponding to a pair site of Arg10-Pro12 in the first 100 amino acids, b aspartate rich motif (DDXXD, c active site final lid and d active site including farnesyl diphosphate (FDP ionization sites and catalytic site in the ADS enzyme, were investigated. Major conclusion: The sequence corresponding to ADS active site was amplified only in A. annua, A. aucheri and A. chamaemelifolia. The negative results obtained with other species could be due to some sequence alteration, such as point mutations or INDELs. We propose A. aucheri and A. chamaemelifolia as two potential candidate species for further characterization, breeding and transferring am1 gene for artemisinin overproduction.

  7. Key Issue

    Directory of Open Access Journals (Sweden)

    Oya Y Rieger

    2012-03-01

    Full Text Available A few months ago, while I was participating in a conference about open access infrastructures, a delegate from a governmental agency asked, “Why does each library need to maintain a repository for their own scientists?” He was rightfully wondering if a broad collaboration in building a network of archives will provide a durable and extensible technology and service framework for ever-increasing digital scholarly content. The ensuing discussion did not offer a plausible response but accentuated that we do not have in place a plan for building an expandable infrastructure to facilitate communication and exchange of information among rapidly proliferating distinct instances of institutional and subject repositories.

  8. National Aeronautics and Space Administration: Overview, FY2007 Budget in Brief, and Key Issues for Congress

    National Research Council Canada - National Science Library

    Morgan, Daniel; Behrens, Carl E

    2006-01-01

    .... The key issue for Congress is how NASA is implementing the Vision for Space Exploration, including whether it is maintaining a balanced portfolio of programs that include science and aeronautics...

  9. Task-Based Pronunciation Teaching and Research: Key Issues and Future Directions

    Science.gov (United States)

    Mora, Joan C.; Levkina, Mayya

    2017-01-01

    This article synthesizes the conclusions of the empirical studies in this special issue and outlines key questions in future research. The research reported in this volume has identified several fundamental issues in pronunciation-focused task design that are discussed in detail and on which suggestions for further research are outlined. One…

  10. Understanding Key Education Issues: How We Got Here and Where We Go from Here

    Science.gov (United States)

    Lynch, Matthew

    2017-01-01

    In this age of education innovation and reform, schools must evolve and react to current policy trends. This accessible book offers research-based insights into six key educational trends and issues that are impacting K-12 learning today: year-round schooling, assessments, educating minorities, anti-intellectualism, issues of social promotion and…

  11. Managing and developing key supplier relationships : An introduction to the special issue, discussion and implications

    NARCIS (Netherlands)

    Ivens, B.; van de Vijver, M.A.R.; Vos, G.C.J.M.

    2013-01-01

    This article provides an introduction to this special issue on managing and developing key supplier relationships. Key suppliers are increasingly seen as strategic assets of buying companies which need careful nurturing to fully utilize their potential for value creation. The six articles of this

  12. Authenticated Blind Issuing of Symmetric Keys for Mobile Access Control System without Trusted Parties

    Directory of Open Access Journals (Sweden)

    Shin-Yan Chiou

    2013-01-01

    Full Text Available Mobile authentication can be used to verify a mobile user’s identity. Normally this is accomplished through the use of logon passwords, but this can raise the secret-key agreement problem between entities. This issue can be resolved by using a public-key cryptosystem, but mobile devices have limited computation ability and battery capacity and a PKI is needed. In this paper, we propose an efficient, non-PKI, authenticated, and blind issued symmetric key protocol for mobile access control systems. An easy-to-deploy authentication and authenticated key agreement system is designed such that empowered mobile devices can directly authorize other mobile devices to exchange keys with the server upon authentication using a non-PKI system without trusted parties. Empowered mobile users do not know the key value of the other mobile devices, preventing users from impersonating other individuals. Also, for security considerations, this system can revoke specific keys or keys issued by a specific user. The scheme is secure, efficient, and feasible and can be implemented in existing environments.

  13. Some Physics And System Issues In The Security Analysis Of Quantum Key Distribution Protocols

    OpenAIRE

    Yuen, Horace P.

    2014-01-01

    In this paper we review a number of issues on the security of quantum key distribution (QKD) protocols that bear directly on the relevant physics or mathematical representation of the QKD cryptosystem. It is shown that the cryptosystem representation itself may miss out many possible attacks which are not accounted for in the security analysis and proofs. Hence the final security claims drawn from such analysis are not reliable, apart from foundational issues about the security criteria that ...

  14. A CEO View of Key Issues in Australian Information Systems Management - 1997

    Directory of Open Access Journals (Sweden)

    Graham Pervan

    1998-05-01

    Full Text Available As part of a research programme on key information systems management issues, a survey of Australasia's largest 500 organisations was conducted to identify which issues were perceived by their chief executive officers (CEOs as being important, problematic and critical over the next three to five years. The results reported are based on a relatively low response rate (though perhaps reasonable for the target group so should be regarded as only exploratory. The most critical issues were revealed to be a mix of technology management issues (IT infrastructure, disaster recovery, strategic management issues (BPR, competitive advantage, information architecture, people management issues (organisational learning, systems development and data management issues (effective use of the data resource, effectiveness/productivity of IS, effectiveness of software development, and their own support systems (EIS/DSS. This reflects their interest in a wide range of issues, but all with an organisation-wide focus. Non-critical issues were mostly related to the individual technologies and the place and role of IS in the organisation. While the CEOs showed some agreement with their chief information officers (CIOs on issues such as the IT infrastructure, competitive advantage, and organisational learning some distinct differences exist, particularly in relation to the quality and effectiveness of systems and processes and also how CEOs and CIOs perceive each other.

  15. Maori responsiveness in health and medical research: key issues for researchers (part 1).

    Science.gov (United States)

    Sporle, Andrew; Koea, Jonathan

    2004-08-06

    Application for contestable government-research funding and ethical approval requires researchers to outline how their intended research project contributes to Maori development or advancement. When formulating their research proposals, the key issues for researchers are research utility, defining Maori, informed consent, confidentiality, issues with human tissues and genetic material, participant remuneration and recognition (koha), intellectual property, and involvement of local Maori health or social services. The most common Maori responsiveness issues in research applications can be readily approached by researchers who address straightforward methodological concerns, by working through precedents established by peers and colleagues, as well as by working with end-users of their research.

  16. Key Questions on the Obama Administration's 2014 Education Budget Request. Issue Brief

    Science.gov (United States)

    New America Foundation, 2013

    2013-01-01

    President Obama sent his fiscal year 2014 budget request to Congress on April 10, 2013. The New America Foundation's Education Policy Program released this subsequent issue brief, "Key Questions on the Obama Administration's 2014 Budget Request." Obama's budget request totals $71.2 billion in appropriations funding for the U.S.…

  17. Several key issues on using 137Cs method for soil erosion estimation

    Science.gov (United States)

    This work was to examine several key issues of using the cesium-137 method to estimate soil erosion rates in order to improve and standardize the method. Based on the comprehensive review and synthesis of a large body of published literature and the author’s extensive research experience, several k...

  18. Gestures and some key issues in the study of language development

    NARCIS (Netherlands)

    Gullberg, Marianne; de Bot, Kees; Volterra, Virginia; Gullberg, 28297

    2008-01-01

    The purpose of the current paper is to outline how gestures can contribute to the study of some key issues in language development. Specifically, we (1) briefly summarise what is already known about gesture in the domains of first and second language development, and development or changes over the

  19. Key Themes and Future Directions in Teaching English to Young Learners: Introduction to the Special Issue

    Science.gov (United States)

    Copland, Fiona; Garton, Sue

    2014-01-01

    Despite being something of a "Cinderella" area of study, research into and informed discussion of teaching young learners is on the increase, perhaps mirroring the increasing numbers of children learning English globally in primary schools. This introductory article reviews key themes and issues in the teaching of English to young…

  20. Key Issues in Sex Education: Reflecting on Teaching, Learning and Assessment

    Science.gov (United States)

    Oerton, Sarah; Bowen, Helen

    2014-01-01

    Drawing upon critical reflections of staff and student experiences of teaching, learning and assessment on an undergraduate module entitled Key Issues in Sex Education, we discuss the strategies used to engage students in debates around sex and relationships education (SRE). To date, there is little research which evaluates how formal assessments…

  1. Building and Strengthening Policy Research Capacity: Key Issues in Canadian Higher Education

    Science.gov (United States)

    Jones, Glen A.

    2014-01-01

    Given the importance of higher education in social and economic development, governments need to build a strong higher education data and policy research infrastructure to support informed decision-making, provide policy advice, and offer a critical assessment of key trends and issues. The author discusses the decline of higher education policy…

  2. Practical issues in decoy-state quantum key distribution based on the central limit theorem

    Science.gov (United States)

    Trushechkin, A. S.; Kiktenko, E. O.; Fedorov, A. K.

    2017-08-01

    Decoy-state quantum key distribution (QKD) is a standard tool for long-distance quantum communications. An important issue in this field is processing the decoy-state statistics taking into account statistical fluctuations (or "finite-key effects"). In this work, we propose and analyze an option for decoy statistics processing, which is based on the central limit theorem. We discuss such practical issues as inclusion of the failure probability of the decoy-state statistical estimates in the total failure probability of a QKD protocol and also taking into account the deviations of the binomially distributed random variables used in the estimations from the Gaussian distribution. The results of numerical simulations show that the obtained estimations are quite tight. The proposed technique can be used as a part of post-processing procedures for industrial quantum key distribution systems.

  3. Nanoscale ferroelectrics and multiferroics key processes and characterization issues, and nanoscale effects

    CERN Document Server

    Alguero, Miguel

    2016-01-01

    This book reviews the key issues in processing and characterization of nanoscale ferroelectrics and multiferroics, and provides a comprehensive description of their properties, with an emphasis in differentiating size effects of extrinsic ones like boundary or interface effects. Recently described nanoscale novel phenomena are also addressed. Organized into three parts it addresses key issues in processing (nanostructuring), characterization (of the nanostructured materials) and nanoscale effects. Taking full advantage of the synergies between nanoscale ferroelectrics and multiferroics, it covers materials nanostructured at all levels, from ceramic technologies like ferroelectric nanopowders, bulk nanostructured ceramics and thick films, and magnetoelectric nanocomposites, to thin films, either polycrystalline layer heterostructures or epitaxial systems, and to nanoscale free standing objects with specific geometries, such as nanowires and tubes at different levels of development. The book is developed from t...

  4. Fertility Preservation: A Key Survivorship Issue for Young Women with Cancer

    OpenAIRE

    Ana M Angarita; Cynae Alonia Lillian Johnson; Amanda eNickles Fader; Christianson, Mindy S.

    2016-01-01

    Fertility preservation in the young cancer survivor is recognized as a key survivorship issue by the American Society of Clinical Oncology and the American Society of Reproductive Medicine. Thus, health-care providers should inform women about the effects of cancer therapy on fertility and should discuss the different fertility preservation options available. It is also recommended to refer women expeditiously to a fertility specialist in order to improve counseling. Women’s age, diagnosis, p...

  5. Key issues in mergers and acquisitions. Healthcare organizations must approach collaborations with caution.

    Science.gov (United States)

    Newman, J A

    1991-05-01

    Most collaborations between healthcare providers are based on a desire to better serve their communities, develop critical mass, eliminate duplicative services, create economies of scale, and enhance survivability. Unfortunately, collaborations may not always produce the benefits desired. Thus careful planning and execution are critical to first determine whether the transaction makes sense and, if it does, to develop strategies that maximize the expected benefits. Whether the participating entities are secular, religious, public, or private, I recommend they consider the following 11 key issues when evaluating or pursuing a merger or acquisition: (1) understand the transaction's magnitude, (2) assess the alternatives, (3) select potential partners carefully, (4) determine and examine threshold issues early, (5) focus on the right issues, (6) agree on a valuation approach, (7) recognize the importance of governance, (8) develop an acceptable structure, and use a memorandum of understanding, (9) establish and adhere to a communications policy, (10) perform due diligence, and (11) recognize the significance of activities after the transaction.

  6. The emerging role of Big Data in key development issues: Opportunities, challenges, and concerns

    Directory of Open Access Journals (Sweden)

    Nir Kshetri

    2014-12-01

    Full Text Available This paper presents a review of academic literature, policy documents from government organizations and international agencies, and reports from industries and popular media on the trends in Big Data utilization in key development issues and its worthwhileness, usefulness, and relevance. By looking at Big Data deployment in a number of key economic sectors, it seeks to provide a better understanding of the opportunities and challenges of using it for addressing key issues facing the developing world. It reviews the uses of Big Data in agriculture and farming activities in developing countries to assess the capabilities required at various levels to benefit from Big Data. It also provides insights into how the current digital divide is associated with and facilitated by the pattern of Big Data diffusion and its effective use in key development areas. It also discusses the lessons that developing countries can learn from the utilization of Big Data in big corporations as well as in other activities in industrialized countries.

  7. Ten years of subproteome investigations in lactic acid bacteria: A key for food starter and probiotic typing.

    Science.gov (United States)

    Mangiapane, E; Mazzoli, R; Pessione, A; Svensson, B; Riedel, K; Pessione, E

    2015-09-08

    The definition of safety and efficacy of food-employed bacteria as well as probiotic strains is a continuous, often unattended, challenge. Proteomic techniques such as 2DE, DIGE and LC/LC-MS/MS are suitable and powerful tools to reveal new aspects (positive and negative) of "known" and "unknown" strains that can be employed in food making and as nutraceutical supplements for human health. Unfortunately, these techniques are not used as extensively as it should be wise. The present report describes the most significant results obtained by our research group in 10years of study on subproteomes in bacteria, chiefly lactic acid bacteria. Production of desired and undesired metabolites, differences between strains belonging to same species but isolated from different ecological niches, the effect of cryoprotectants on survival to lyophilization as well as the adhesive capability of strains, were elucidated by analysis of cytosolic, membrane-enriched, surface and extracellular proteomes. The present review opens a window on a yet largely underexplored field and highlights the huge potential of subproteome investigations for more rational choice of microbial strains as food starters, probiotics and for production of nutraceuticals. These analyses will hopefully contribute to manufacturing safer and healthier food and food supplements in the near future. This article is part of a Special Issue entitled: HUPO 2014. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Integrating Variable Renewable Energy into the Grid: Key Issues, Greening the Grid (Spanish Version)

    Energy Technology Data Exchange (ETDEWEB)

    2016-04-01

    This is the Spanish version of 'Greening the Grid - Integrating Variable Renewable Energy into the Grid: Key Issues'. To foster sustainable, low-emission development, many countries are establishing ambitious renewable energy targets for their electricity supply. Because solar and wind tend to be more variable and uncertain than conventional sources, meeting these targets will involve changes to power system planning and operations. Grid integration is the practice of developing efficient ways to deliver variable renewable energy (VRE) to the grid. Good integration methods maximize the cost-effectiveness of incorporating VRE into the power system while maintaining or increasing system stability and reliability. When considering grid integration, policy makers, regulators, and system operators consider a variety of issues, which can be organized into four broad topics: New Renewable Energy Generation, New Transmission, Increased System Flexibility, and Planning for a High RE Future.

  9. The key physics and technology issues in the intense-beam proton accelerators

    CERN Document Server

    Fu Shin Ian; Guan Xia Ling

    2002-01-01

    Beam power is required to raise one order in the next generation spallation neutron source. There are still some physics and technology difficulties need to be overcome, even though no fatal obstacle exists due to the rapid development of the technology in intense-beam accelerator in recent years. Therefore, it is highly demanded to clarify the key issues and to lunch an R and D program to break through the technological barriers before start to build the expansive machine. The new technological challenge arises from the high beam current, the high accelerator power and the high demand on the reliability and stability of the accelerator operation. The will discuss these issues and the means to resolve them, as well as the state of the art in a few of major technological disciplines. Finally, the choice the framework of intense-beam accelerator is discussed

  10. Assessing stakeholder's experience and sensitivity on key issues for the economic growth of organic aquaculture production

    DEFF Research Database (Denmark)

    Lembo, Giuseppe; Jokumsen, Alfred; Spedicato, Maria Teresa

    2018-01-01

    , and specifically, of the aquaculture system. A survey focused on the current EU regulatory framework was carried out to elicit stakeholders’ preferences, knowledge and experience on key issues for the development of organic aquaculture, supported by science-based regulations. The survey was completed by 65...... stakeholders belonging to several categories, and it was supported by the implementation of the Analytic Hierarchy Process method. Stakeholders’ preferences were elicited on organic production methods and control systems, the quality of the environment and organic products, fish health and welfare. The views...... expressed by the participants revealed both competence and awareness, despite the complexity of the subject. Several ideas and useful suggestions emerged regarding unresolved technical issues. In addition, the need for a targeted communication strategy on the quality of organic aquaculture products...

  11. Key issues in the management of patients with systemic lupus erythematosus: latest developments and clinical implications

    Science.gov (United States)

    Jordan, Natasha; D’Cruz, David

    2015-01-01

    Systemic lupus erythematous (SLE) is a chronic multisystem disease with significant associated morbidity and mortality. A deeper understanding of the pathogenesis of SLE has led to the development of biologic agents, primarily targeting B cells and others inhibiting costimulatory molecules, type I interferons and cytokines such as interleukin-6. Several of these agents have been studied in clinical trials; some have shown promise while others have yielded disappointing results. Economic and regulatory issues continue to hamper the availability of such therapies for SLE patients. With increasing recognition that recurrent flares of disease activity lead to long-term damage accrual, one of the most important recent developments in patient management has been the concept of treat-to-target in SLE while minimizing patient exposure to excessive corticosteroid and other immunosuppressive therapy. This article reviews these key issues in SLE management, outlining recent developments and clinical implications for patients. PMID:26622325

  12. Ten Lectures on Spoken Language and Gesture from the Perspective of Cognitive Linguistics: Issues of Dynamicity and Multimodality

    NARCIS (Netherlands)

    Cienki, A.J.

    2017-01-01

    Cognitive linguistics is purported to be a usage-based approach, yet only recently has research in some of its subfields turned to spontaneous spoken (versus written) language data. The collection of Alan Cienki’s Ten Lectures on Spoken Language and Gesture from the Perspective of Cognitive

  13. eHealth in Wound Care,- overview and key issues to consider before implementation

    DEFF Research Database (Denmark)

    Moore, Zena; Angel, Donna; Bjerregaard, Julie

    2015-01-01

    Purpose This document aims to provide wound care clinicians with a rapid and structured overview of the key issues related to use of eHealth applications (telemedicine and telehealth) within wound care. This includes: • An overview of terminology and available literature • Guidance on the methodo......Purpose This document aims to provide wound care clinicians with a rapid and structured overview of the key issues related to use of eHealth applications (telemedicine and telehealth) within wound care. This includes: • An overview of terminology and available literature • Guidance...... on the methodology for evaluation of eHealth solutions • An introduction to and discussion of the potential benefits of eHealth technologies in wound care, and the possible barriers to their implementation • Recommendations for ensuring a good implementation process and supporting involvement of wound care...... professionals in safeguarding that eHealth solutions meet the needs of the patients. Methodology The document sections lean on the structure and focus areas of the Model for ASsessment of Telemedicine (MAST) which defines crucial items to evaluate an eHealth application. The content of the document is developed...

  14. Mapping the key issues shaping the landscape of global public health.

    Science.gov (United States)

    Ager, Alastair; Yu, Gary; Hermosilla, Sabrina

    2012-01-01

    A survey of global health experts attending an invited meeting provided a means to map key issues perceived to be shaping emerging global public health agendas. Eighty-five participants proposed three major issues likely to have the most significant impact on the field of global health in the coming years. Six raters grouped the resultant items, with multi-dimensional scaling (MDS) analysis producing a composite two-dimensional map depicting the overall patterning of items. Thematic clusters were incorporated within four major domains: changing health and prevention needs (15% of items), globalisation and global health governance (33% of items), transforming health systems (30% of items) and innovations in science and technology (7% of items). The remaining 15% of items addressed forms of environmental change. The distribution of items across domains was not significantly influenced by the current professional role of participants, their current location in the 'global north' or 'global south' or their region of focus (although the latter approached threshold significance). The constraints on interpretation imposed by the biases influencing participation in the survey are noted. However, the exercise suggests the potential for coherently defining shared agendas for diverse stakeholders to address emerging priorities. The closer integration of environmental concerns with other global public issues is clearly warranted.

  15. Ten new species of Rhagovelia in the angustipes complex (Hemiptera: Heteroptera: Veliidae) from Colombia, with a key to the Colombian species.

    Science.gov (United States)

    Padilla-Gil, Dora Nancy

    2015-12-21

    Ten new species of Rhagovelia are described from Colombia as follows: Rhagovelia penta sp. n., and Rhagovelia santanderi sp. n., from the Upper and Middle Magdalena River Valley respectively; Rhagovelia carina sp. n., Rhagovelia tricoma sp. n., and Rhagovelia barbacoensis sp. n., from Altaquer, Río Ñambi; Rhagovelia caunapi sp. n. from Río Caunapi; Rhagovelia tumaquensis sp. n., from Tumaco, Río Mejicano; Rhagovelia jagua sp. n., from Eastern Andes; Rhagovelia mocoa sp. n. and Rhagovelia umbria sp. n., from Amazonas region. Rhagovelia tantilla Drake & Harris is recorded from Colombia, for the first time; the description of macropterous morph of Rhagovelia espriella Padilla-Gil, 2011 and a key to the Rhagovelia, angustipes complex of Colombian species are provided.

  16. Interoperability of electronic health records and personal health records: key interoperability issues associated with information exchange.

    Science.gov (United States)

    Pringle, Simone; Lippitt, Alex

    2009-01-01

    As patients receive medical care, their clinical history may be tracked and recorded by multiple electronic systems developed by independent vendors. Medical providers might use electronic health record (EHR) software tailored to the needs of trained medical personnel, whereas patients may interact with personal health records (PHR). The purpose of this essay is to identify the key interoperability issues associated with the information exchange between these two types of systems and offer an approach for enhancing interoperability. This article is part of a series of unpublished essays titled A Community View on How Personal Health Records Can Improve Patient Care and Outcomes in Many Healthcare Settings, a collaborative project of Northern Illinois Physicians For Connectivity and the Coalition for Quality and Patient Safety of Chicagoland. For further information on how you can obtain copies of the complete work, contact the principle Dr. Stasia Kahn at Stash5@sbcglobal.net.

  17. Key issues in the pharmaceutical industry: consequences on R&D.

    Science.gov (United States)

    Malik, Nafees N

    2009-01-01

    Drug discovery is hard, and is becoming progressively harder, with the passage of time! No other field has to handle such an interplay of scientific, fiscal and political factors. The rewards are, nonetheless, worth it: people now live healthier and longer lives than at any point of time in the past. Times are, however, hard for pharmaceutical companies: research and development (R&D) costs are spiralling out of control. New drug approvals, on the other hand, have hit a record low; and the situation is expected to worsen, now that the FDA seems to be exhibiting stricter drug approval standards. Other issues also exacerbate circumstances: huge numbers of blockbuster medicines, which drugmakers rely on to generate their incomes, are coming off patent, and generic competition is intensifying. Both public and investor confidence in the industry have fallen drastically owing to rising drug prices, product safety concerns and late-stage clinical trial failures. This article discusses the key issues that pharmaceutical companies face and in particular the implications they have for the R&D process. I finish by suggesting how drugmakers should change their R&D strategies to succeed.

  18. Multiple-Robot Systems for USAR: Key Design Attributes and Deployment Issues

    Directory of Open Access Journals (Sweden)

    Choon Yue Wong

    2011-03-01

    Full Text Available The interaction between humans and robots is undergoing an evolution. Progress in this evolution means that humans are close to robustly deploying multiple robots. Urban search and rescue (USAR can benefit greatly from such capability. The review shows that with state of the art artificial intelligence, robots can work autonomously but still require human supervision. It also shows that multiple robot deployment (MRD is more economical, shortens mission durations, adds reliability as well as addresses missions impossible with one robot and payload constraints. By combining robot autonomy and human supervision, the benefits of MRD can be applied to USAR while at the same time minimizing human exposure to danger. This is achieved with a single-human multiple-robot system (SHMRS. However, designers of the SHMRS must consider key attributes such as the size, composition and organizational structure of the robot collective. Variations in these attributes also induce fluctuations in issues within SHMRS deployment such as robot communication and computational load as well as human cognitive workload and situation awareness (SA.Research is essential to determine how the attributes can be manipulated to mitigate these issues while meeting the requirements of the USAR mission.

  19. Multiple-Robot Systems for USAR: Key Design Attributes and Deployment Issues

    Directory of Open Access Journals (Sweden)

    Choon Yue Wong

    2011-03-01

    Full Text Available The interaction between humans and robots is undergoing an evolution. Progress in this evolution means that humans are close to robustly deploying multiple robots. Urban search and rescue (USAR can benefit greatly from such capability. The review shows that with state of the art artificial intelligence, robots can work autonomously but still require human supervision. It also shows that multiple robot deployment (MRD is more economical, shortens mission durations, adds reliability as well as addresses missions impossible with one robot and payload constraints. By combining robot autonomy and human supervision, the benefits of MRD can be applied to USAR while at the same time minimizing human exposure to danger. This is achieved with a single-human multiple-robot system (SHMRS. However, designers of the SHMRS must consider key attributes such as the size, composition and organizational structure of the robot collective. Variations in these attributes also induce fluctuations in issues within SHMRS deployment such as robot communication and computational load as well as human cognitive workload and situation awareness (SA. Research is essential to determine how the attributes can be manipulated to mitigate these issues while meeting the requirements of the USAR mission.

  20. Family-friendliness in business as a key issue for the future.

    Science.gov (United States)

    Stutzer, Erich

    2012-01-01

    These days family-friendliness is a key issue for the future of businesses. Investments in a family conscious personnel policy are considered as forward-looking decisions in companies. This happens against the background of a sustainable personnel policy in times of a decrease in the number of employable persons, an increasing shortage of skilled workers and an ageing workforce. Family-friendly working conditions are becoming a key factor in the competition for staff. When choosing an employer, family-friendliness has become a crucial topic. Employment participation and skills of women, especially of mothers, have greatly increased. To facilitate the realisation of their wish to return to paid employment, however, measures to reconcile work and family are required. Family-conscious measures have been proven to lead to higher employee productivity. Job satisfaction and motivation of employees and accumulation of human capital increase, absenteeism declines, the return of investment rises. Fields of activity for family-friendly measures in companies range from working arrangements, parental leave and re-entry programmes and various child care offers to services for families. In connection with the demographic development the demand for a better reconciliation of work and elder care should in future become ever more important, just as the upkeep of the occupational skills and working capacity of an ageing workforce. Family-friendliness has to become an integral part of corporate culture.

  1. Towards optimised information about clinical trials; identification and validation of key issues in collaboration with cancer patient advocates

    DEFF Research Database (Denmark)

    Dellson, P; Nilbert, M; Bendahl, P-O

    2011-01-01

    for improvements, 21 key issues were defined and validated through a questionnaire in an independent group of breast cancer patient advocates. Clear messages, emotionally neutral expressions, careful descriptions of side effects, clear comparisons between different treatment alternatives and information about...

  2. Prospects and applications near ferroelectric quantum phase transitions: a key issues review

    Science.gov (United States)

    Chandra, P.; Lonzarich, G. G.; Rowley, S. E.; Scott, J. F.

    2017-11-01

    The emergence of complex and fascinating states of quantum matter in the neighborhood of zero temperature phase transitions suggests that such quantum phenomena should be studied in a variety of settings. Advanced technologies of the future may be fabricated from materials where the cooperative behavior of charge, spin and current can be manipulated at cryogenic temperatures. The progagating lattice dynamics of displacive ferroelectrics make them appealing for the study of quantum critical phenomena that is characterized by both space- and time-dependent quantities. In this key issues article we aim to provide a self-contained overview of ferroelectrics near quantum phase transitions. Unlike most magnetic cases, the ferroelectric quantum critical point can be tuned experimentally to reside at, above or below its upper critical dimension; this feature allows for detailed interplay between experiment and theory using both scaling and self-consistent field models. Empirically the sensitivity of the ferroelectric T c’s to external and to chemical pressure gives practical access to a broad range of temperature behavior over several hundreds of Kelvin. Additional degrees of freedom like charge and spin can be added and characterized systematically. Satellite memories, electrocaloric cooling and low-loss phased-array radar are among possible applications of low-temperature ferroelectrics. We end with open questions for future research that include textured polarization states and unusual forms of superconductivity that remain to be understood theoretically.

  3. Key Durability Issues with Mullite-Based Environmental Barrier Coatings for Si-Based Ceramics

    Science.gov (United States)

    Lee, Kang N.

    2000-01-01

    Plasma-sprayed mullite (3Al2O3.2SiO2) and mullite/yttria-stabilized-zirconia (YSZ) dual layer coatings have been developed to protect silicon -based ceramics from environmental attack. Mullite-based coating systems show excellent durability in air. However, in combustion environments, corrosive species such as molten salt or water vapor penetrate through cracks in the coating and attack the Si-based ceramics along the interface. Thus the modification of the coating system for enhanced crack-resistance is necessary for long-term durability in combustion environments. Other key durability issues include interfacial contamination and coating/substrate bonding. Interfacial contamination leads to enhanced oxidation and interfacial pore formation, while a weak coating/substrate bonding leads to rapid attack of the interface by corrosive species, both of which can cause a premature failure of the coating. Interfacial contamination can be minimized by limiting impurities in coating and substrate materials. The interface may be modified to improve the coating/substrate bond.

  4. Key Issues for Navigation and Time Dissemination in NASA's Space Exploration Program

    Science.gov (United States)

    Nelson, R. A.; Brodsky, B.; Oria, A. J.; Connolly, J. W.; Sands, O. S.; Welch, B. W.; Ely T.; Orr, R.; Schuchman, L.

    2006-01-01

    The renewed emphasis on robotic and human missions within NASA's space exploration program warrants a detailed consideration of how the positions of objects in space will be determined and tracked, whether they be spacecraft, human explorers, robots, surface vehicles, or science instrumentation. The Navigation Team within the NASA Space Communications Architecture Working Group (SCAWG) has addressed several key technical issues in this area and the principle findings are reported here. For navigation in the vicinity of the Moon, a variety of satellite constellations have been investigated that provide global or regional surface position determination and timely services analogous to those offered by GPS at Earth. In the vicinity of Mars, there are options for satellite constellations not available at the Moon due to the gravitational perturbations from Earth, such as two satellites in an aerostationary orbit. Alternate methods of radiometric navigation as considered, including one- and two-way signals, as well as autonomous navigation. The use of a software radio capable of receiving all available signal sources, such as GPS, pseudolites, and communication channels, is discussed. Methods of time transfer and dissemination are also considered in this paper.

  5. Transdisciplinary research for complex One Health issues: a scoping review of key concepts.

    Science.gov (United States)

    Min, B; Allen-Scott, L K; Buntain, B

    2013-11-01

    In order to address the complexity inherent in researching One Health (OH) issues, we support the concept that researchers must transcend individual disciplinary and non-disciplinary boundaries, and move into the realm of transdisciplinary (TD) research approaches. For the purposes of this paper we use the term OH and the concept that OH research is conducted to solve complex health challenges at the animal-human--human-ecosystem interface. TD goes beyond interdisciplinary research to engages disciplines and communities through a unified conceptual framework. In this scoping review we investigated key concepts, definitions and themes in OH and TD based on the peer reviewed literature. We identified nine emerging themes in TD research: (1) education, (2) conflict amongst disciplines, (3) effective communication, (4) shared conceptual framework, (5) leadership, (6) perceived power differentials, (7) community-based methodologies, (8) support for TD research and (9) time and effort. This review provides a synthesized knowledge base that describes the nature, extent of evidence and challenges of engaging in TD initiatives. This knowledge base further provides a foundation for those interested in developing improved strategies for TD collaborative and cross-sectoral research in OH. Copyright © 2013. Published by Elsevier B.V.

  6. Prospects and applications near ferroelectric quantum phase transitions: a key issues review.

    Science.gov (United States)

    Chandra, P; Lonzarich, G G; Rowley, S E; Scott, J F

    2017-11-01

    The emergence of complex and fascinating states of quantum matter in the neighborhood of zero temperature phase transitions suggests that such quantum phenomena should be studied in a variety of settings. Advanced technologies of the future may be fabricated from materials where the cooperative behavior of charge, spin and current can be manipulated at cryogenic temperatures. The progagating lattice dynamics of displacive ferroelectrics make them appealing for the study of quantum critical phenomena that is characterized by both space- and time-dependent quantities. In this key issues article we aim to provide a self-contained overview of ferroelectrics near quantum phase transitions. Unlike most magnetic cases, the ferroelectric quantum critical point can be tuned experimentally to reside at, above or below its upper critical dimension; this feature allows for detailed interplay between experiment and theory using both scaling and self-consistent field models. Empirically the sensitivity of the ferroelectric T c's to external and to chemical pressure gives practical access to a broad range of temperature behavior over several hundreds of Kelvin. Additional degrees of freedom like charge and spin can be added and characterized systematically. Satellite memories, electrocaloric cooling and low-loss phased-array radar are among possible applications of low-temperature ferroelectrics. We end with open questions for future research that include textured polarization states and unusual forms of superconductivity that remain to be understood theoretically.

  7. Consumer understanding and nutritional communication: key issues in the context of the new EU legislation.

    Science.gov (United States)

    van Trijp, Hans C M

    2009-12-01

    Nutrition communication by means of nutrition and health claims and otherwise, holds the potential to contribute to public health by stimulating informed healthier food choices and enhanced health-focussed competition in the market place, provided that the health messages are trustworthy (i.e. scientifically substantiated) and correctly used and interpreted by the consumer. Not surprisingly, these two considerations constitute the cornerstone of the new EU legislation on nutrition and health claims, in which evidence for consumer understanding of nutrition and health claims is a new requirement. To review some of the key issues in consumer understanding of nutritional communication as a basis for reflection on the consumer understanding element of the new EU legislation on nutrition and health claims. There is a need for more methodologically advanced research in consumer understanding of nutrition and health claims as a basis for truly assessing the real-life use of such information and its actual effect on consumer food choices. Such approaches are pertinent in light of the evaluation and approval process of (new) nutrition and health claims as required under the new EU legislation on nutrition and health claims.

  8. Geographical location and key sensitivity issues of post-industrial regions in Europe.

    Science.gov (United States)

    Stuczynski, Tomasz; Siebielec, Grzegorz; Korzeniowska-Puculek, Renata; Koza, Piotr; Pudelko, Rafal; Lopatka, Artur; Kowalik, Monika

    2009-04-01

    Primary objectives of our work were to spatially delineate post industrial areas of the EU-27 and indicate key environmental, social and economic sensitivity issues for these regions. The density of industrial sites within NUTS-x regions for EU-27 countries was assessed by using CORINE 2000 land cover layer. A development of postindustrial society in Europe represents a strong geographic diversity. There are distinct historical and current differences between regions which form major groups, comprising similar internal characteristics and definable trends in environmental and socioeconomic sense. Regions grouped into postindustrial clusters are fundamentally different from the European average, and are facing specific problems related to global market and political changes. Eastern postindustrial regions can be characterized as socially and economically weak, exhibiting high unemployment rate, low GDP, negative population growth and a strong environmental pressure, represented by a high density of dump sites. Most of the western EU postindustrial areas have been successfully recovered and moved into new economy as shown by most of the indicators. In urban postindustrial zones, however, emission sources of pollutants seem to continually be a major problem--not necessarily in terms of exceeding thresholds, but through a remarkable difference in the amount of pollutants produced relative to other regions.

  9. [Full attention to several key issues in surgical treatment for the elderly patients with gastrointestinal cancer].

    Science.gov (United States)

    Zhu, Zhenggang

    2016-05-01

    With the development of population aging in our country, the incidence of gastrointestinal cancer is increasing. The risk of developing gastrointestinal cancer in elderly over 75 years was 5-6 times and the risk of death of gastrointestinal cancer was 7-8 times of the general population. As compared to non-elderly, the incidence of gastric cancer was not decreased obviously but the total incidence of colorectal cancer was increased more quickly. Therefore, screening of gastrointestinal cancer should be performed in the elderly for early discovery, diagnosis and treatment. Because of the insidious onset of the illness in elderly patients, gastrointestinal cancers are mostly diagnosed at advanced or late stage (stage III or IV). Well differentiated cancer is more common, such as papillary or tubular adenocarcinoma. Lauren type, Borrmann II or III are more common in gastric cancer, which are relatively favorable. Compared with non-elderly patients, many elderly patients also suffer from comorbid diseases with higher operation risk and postoperative complication rates. Therefore, we must pay great attention to the perioperative management and the surgical operation for the elderly patients. In this paper, several key issues involved the development trend of incidence and mortality of gastrointestinal cancer, the clinicopathological characteristics, the comorbidity and surgical treatment in the elderly patients with gastrointestinal cancer will be elaborated, aiming at promoting further attention to the clinical therapeutic strategies, management measures and prognostic factors for the elderly patients with gastrointestinal cancer.

  10. Doubly-Special Relativity: Facts, Myths and Some Key Open Issues

    Directory of Open Access Journals (Sweden)

    Giovanni Amelino-Camelia

    2010-03-01

    Full Text Available I report, emphasizing some key open issues and some aspects that are particularly relevant for phenomenology, on the status of the development of “doubly-special” relativistic (“DSR” theories with both an observer-independent high-velocity scale and an observer-independent small-length/large-momentum scale, possibly relevant for the Planck-scale/quantum-gravity realm. I also give a true/false characterization of the structure of these theories. In particular, I discuss a DSR scenario without modification of the energy-momentum dispersion relation and without the қ-Poincaré Hopf algebra, a scenario with deformed Poincaré symmetries which is not a DSR scenario, some scenarios with both an invariant length scale and an invariant velocity scale which are not DSR scenarios, and a DSR scenario in which it is easy to verify that some observable relativistic (but non-special-relativistic features are insensitive to possible nonlinear redefinitions of symmetry generators.

  11. Transboundary Movements of Genetically Modified Organisms and the Cartagena Protocol: Key Issues and Concerns

    Directory of Open Access Journals (Sweden)

    Odile J Lim Tung

    2014-12-01

    Full Text Available Biotechnology or the engineering of the genetic material of species can give way to avenues of possibilities for the benefit of people, fauna and flora but also has the potential of posing untold and undiscovered threats to human beings and other living organisms. One of the first attempts to legislate on international rules on biotechnology can be traced back to article 19 of the Convention on Biological Diversity (CBD in 1992. The CBD is indeed the first international legal instrument apart from the then European Community’s relevant directives to suggest that biotechnology is a matter of concern for the international community while providing a basis upon which more detailed procedures would be elaborated in the field of biosafety. While the CBD includes international rules on access to genetic resources, access to and the transfer of technology, the handling of biotechnology and the distribution of its benefits, it does not include a detailed regulation on genetically modified organisms (GMOs and their possible adverse effects on the environment, human and animal health. It was only with the coming into existence of the Cartagena Protocol on Biosafety (Cartagena Protocol to the CBD in 2000 that the safe transfer, handling and use of living modified organisms (LMOs such as genetically engineered plants, animals, and microbes were at last being catered for, albeit leaving aside the broader categories of GMOs. Due to the need for the negotiators of this protocol to make compromises, there were still key issues on the international biosafety framework pertaining mainly to the scope of the GMOs to be covered by this protocol and by the Advanced Informed Agreement procedure; identification and traceability issues; and liability and redress issues. Nine years after the entry into force of the Cartagena Protocol the transboundary movements of GMOs have clearly increased with new categories of GMOs and genetically modified products to regulate. The

  12. An Improved Methodology to Overcome Key Issues in Human Fecal Metagenomic DNA Extraction

    Directory of Open Access Journals (Sweden)

    Jitendra Kumar

    2016-12-01

    Full Text Available Microbes are ubiquitously distributed in nature, and recent culture-independent studies have highlighted the significance of gut microbiota in human health and disease. Fecal DNA is the primary source for the majority of human gut microbiome studies. However, further improvement is needed to obtain fecal metagenomic DNA with sufficient amount and good quality but low host genomic DNA contamination. In the current study, we demonstrate a quick, robust, unbiased, and cost-effective method for the isolation of high molecular weight (>23 kb metagenomic DNA (260/280 ratio >1.8 with a good yield (55.8 ± 3.8 ng/mg of feces. We also confirm that there is very low human genomic DNA contamination (eubacterial: human genomic DNA marker genes = 227.9:1 in the human feces. The newly-developed method robustly performs for fresh as well as stored fecal samples as demonstrated by 16S rRNA gene sequencing using 454 FLX+. Moreover, 16S rRNA gene analysis indicated that compared to other DNA extraction methods tested, the fecal metagenomic DNA isolated with current methodology retains species richness and does not show microbial diversity biases, which is further confirmed by qPCR with a known quantity of spike-in genomes. Overall, our data highlight a protocol with a balance between quality, amount, user-friendliness, and cost effectiveness for its suitability toward usage for culture-independent analysis of the human gut microbiome, which provides a robust solution to overcome key issues associated with fecal metagenomic DNA isolation in human gut microbiome studies.

  13. North Korean nuclear issues and the LWR project; analysis of the key technologies

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Byung Koo; Kwack, E. H.; Shin, J. S.; An, J. S.; Lee, J. U.; Kim, H. T.; Kim, J. S.; Yoon, Y. C

    2000-11-01

    Year 2000 will be remembered as an epoch making period between two Koreas. Korean nuclear industries became activated with the KEDO LWR main contracts entering into force in February, 2000. Respective design, manufacturing and construction activities are mobilized in accordance with the total project schedule of about 100 months. What started out as the nuclear power plant design standardization project in the early '80s, is now being implemented as repeat construction of KSNPs at Yonggwang and Ulchin sites as well as at Kumho site in the DPRK. However, the KEDO construction schedule and the past nuclear inconsistency issues are closely linked due to the nonproliferation concerns. In practice, the IAEA must come to the conclusion that the correctness and completeness must be fulfilled before delivery of the first key component for the KEDO LWR unit 1. While the IAEA verification process tends to focus on the nuclear materials accountancy control, longer term objective between two Koreas is bound to take the form of confidence building. It is necessary to analyse the nuclear research and production facilities in order to make proper evaluation of a nation's nuclear capabilities. Close assessment on development status of graphite moderated reactors and their operation history, spent fuel reprocessing facilities, and HEU production capabilities would be essential. In addition, illicit trafficking possibilities should be addressed. Chapter 1 describes the graphite moderated reactors in general; Chapter 2 describes various reprocessing processes and their detection capabilities; Chapter 3 contains possible uranium enrichment processes with their detection capabilities, and Chapter 4 summarizes the international treaties in illicit trafficking control with the IAEA database.

  14. An Improved Methodology to Overcome Key Issues in Human Fecal Metagenomic DNA Extraction.

    Science.gov (United States)

    Kumar, Jitendra; Kumar, Manoj; Gupta, Shashank; Ahmed, Vasim; Bhambi, Manu; Pandey, Rajesh; Chauhan, Nar Singh

    2016-12-01

    Microbes are ubiquitously distributed in nature, and recent culture-independent studies have highlighted the significance of gut microbiota in human health and disease. Fecal DNA is the primary source for the majority of human gut microbiome studies. However, further improvement is needed to obtain fecal metagenomic DNA with sufficient amount and good quality but low host genomic DNA contamination. In the current study, we demonstrate a quick, robust, unbiased, and cost-effective method for the isolation of high molecular weight (>23kb) metagenomic DNA (260/280 ratio >1.8) with a good yield (55.8±3.8ng/mg of feces). We also confirm that there is very low human genomic DNA contamination (eubacterial: human genomic DNA marker genes=227.9:1) in the human feces. The newly-developed method robustly performs for fresh as well as stored fecal samples as demonstrated by 16S rRNA gene sequencing using 454 FLX+. Moreover, 16S rRNA gene analysis indicated that compared to other DNA extraction methods tested, the fecal metagenomic DNA isolated with current methodology retains species richness and does not show microbial diversity biases, which is further confirmed by qPCR with a known quantity of spike-in genomes. Overall, our data highlight a protocol with a balance between quality, amount, user-friendliness, and cost effectiveness for its suitability toward usage for culture-independent analysis of the human gut microbiome, which provides a robust solution to overcome key issues associated with fecal metagenomic DNA isolation in human gut microbiome studies. Copyright © 2016 The Authors. Production and hosting by Elsevier Ltd.. All rights reserved.

  15. Key issues in the computational simulation of GPCR function: representation of loop domains

    Science.gov (United States)

    Mehler, E. L.; Periole, X.; Hassan, S. A.; Weinstein, H.

    2002-11-01

    Some key concerns raised by molecular modeling and computational simulation of functional mechanisms for membrane proteins are discussed and illustrated for members of the family of G protein coupled receptors (GPCRs). Of particular importance are issues related to the modeling and computational treatment of loop regions. These are demonstrated here with results from different levels of computational simulations applied to the structures of rhodopsin and a model of the 5-HT2A serotonin receptor, 5-HT2AR. First, comparative Molecular Dynamics (MD) simulations are reported for rhodopsin in vacuum and embedded in an explicit representation of the membrane and water environment. It is shown that in spite of a partial accounting of solvent screening effects by neutralization of charged side chains, vacuum MD simulations can lead to severe distortions of the loop structures. The primary source of the distortion appears to be formation of artifactual H-bonds, as has been repeatedly observed in vacuum simulations. To address such shortcomings, a recently proposed approach that has been developed for calculating the structure of segments that connect elements of secondary structure with known coordinates, is applied to 5-HT2AR to obtain an initial representation of the loops connecting the transmembrane (TM) helices. The approach consists of a simulated annealing combined with biased scaled collective variables Monte Carlo technique, and is applied to loops connecting the TM segments on both the extra-cellular and the cytoplasmic sides of the receptor. Although this initial calculation treats the loops as independent structural entities, the final structure exhibits a number of interloop interactions that may have functional significance. Finally, it is shown here that in the case where a given loop from two different GPCRs (here rhodopsin and 5-HT2AR) has approximately the same length and some degree of sequence identity, the fold adopted by the loops can be similar. Thus

  16. Key Issue: Text mining, copyright and the benefits and barriers to innovation

    Directory of Open Access Journals (Sweden)

    Torsten Reimer

    2012-07-01

    Full Text Available Do you want to cure cancer? It doesn’t matter whether your research is about solving one of the grand challenges of humanity or addressing a more humble question – your first step is likely to be looking at what others have done before. Due to the ever-increasing number of scholarly publications (about 1.5 million new articles published every year, building up an overview of any field of study is an extremely time-consuming process. In prominent topics such as cancer research, it is even more difficult: for the last ten years alone, the UK PubMed Central (UKPMC database lists 312,308 citations with the word ‘cancer’ in the title – browsing them at the leisurely pace of 85 per day will take you about ten years. And by that time, ten years’ worth of new articles on cancer will have appeared. To make such a search even more complex, relevant articles may not feature the keyword ‘cancer’ and critical information may be hiding in a footnote within a completely unrelated publication. There is huge potential for advancing knowledge by systematically identifying, analysing and cross-referencing existing research, but the work required is prohibitively time-consuming and expensive. Unless we use machines to help us – and that is where text mining comes into play.

  17. International Policy Framework for Protecting Critical Information Infrastructure: A Discussion Paper Outlining Key Policy Issues

    NARCIS (Netherlands)

    Brown, B.; Goetz, E.; Verhoest, P.; Helmus, S.; Luiijf, H.A.M.; Bruce, R.; Dynes, S.; Brechbuhl, H.

    2005-01-01

    Cyber security is a uniquely challenging policy issue with a wide range of public and private stakeholders within countries and beyond national boundaries. This executive summary and the full discussion paper delineate the need on a high priority basis to address cyber security issues and develop an

  18. Developing Communities of Enquiry: Dealing with Social and Ethical Issues in Science at Key Stage 3

    Science.gov (United States)

    Dunlop, Lynda; Humes, Gill; Clarke, Linda; Martin, Valerie McKelvey

    2011-01-01

    Reproductive technologies, drug discovery and exploration of the universe are areas of contemporary research that raise issues for individuals and society. Forward Thinking, Northern Ireland uses the development of communities of enquiry to promote discussion of these and other social and ethical issues in science with students aged 11-14 years.…

  19. Translating key methodological issues into technological advancements when running in-situ experiments in sports: An example from sailing

    NARCIS (Netherlands)

    Pluijms, J.P.; Canal Bruland, R.; Kats, S.; Savelsbergh, G.J.P.

    2013-01-01

    In recent years there has been an increasing interest in capturing and understanding skilled performance by studying complex perceptual-motor skills. In this context, we identify and discuss key methodological issues that are particularly relevant when aiming to translate sport scientific knowledge

  20. Foreign Affairs, Defense, and Trade: Key Issues for the 110th Congress

    National Research Council Canada - National Science Library

    Ribando, Clare M; Vaughn, Bruce

    2006-01-01

    .... A major issue confronting the new Congress is what to do in Iraq. The Baker/Hamilton-led Iraq Study Group recommended pursuing a new diplomatic initiative, including negotiations with Iran and Syria...

  1. Patient safety and interprofessional education: A report of key issues from two interprofessional workshops

    OpenAIRE

    Anderson, Elizabeth; Gray, Richard; Price, Kim

    2017-01-01

    This article presents the outcomes of two workshops which explored historical and recent issues on patient safety that directly relate to leaders in the interprofessional field. The article considers the impact of flattened team-based structures where collaborative working constantly considers safe patient-centred high-quality care. These issues are mainly rooted in changes within a UK context, but the historical case studies present situations which could enlighten and enliven discussions of...

  2. Conference communication. Managing change in tourism destinations: Key issues and current trends.

    OpenAIRE

    M. M. Mariani; Buhalis, Dimitrios; Longhi, C.; Vitouladiti, O.

    2013-01-01

    This conference communication illustrates the major outcomes emerging from the EIASM Conference on Tourism Management and Tourism Related Issues held in Nice (France), September 20-21, 2012. While a number of managerial issues pertaining to the tourism field were dealt with, this communication covers three specific areas of interest for destination management and marketing: (1) the increasing competition among tourism destinations and the rise and consolidation of BRIC countries as outbound t...

  3. The economics of biomedical waste irradiation: Key issues influencing total cost

    Science.gov (United States)

    Wilson, Bruce K.

    1993-07-01

    Each application of gamma irradiation technology is different in one or more significant respects. Disinfections of Biomedical Wastes presents similar technical challenges to sterilization of Medical Supplies, but the economic issues are dramatically different. Regulatory requirements, site and technology approvals, waste separation/mixing, transportation, irradiation utilization, economies of scale, and end-product disposal can each have a probibitive or enabling effect on whether irradiation of biomedical wastes makes good financial sense in particular situation. This paper discusses each of these issues.

  4. Energy investments and environmental implications: key policy issues in developing countries

    Energy Technology Data Exchange (ETDEWEB)

    Siddayao, Corazon M. (World Bank Washington, DC (USA). Economic Development Institute)

    1992-03-15

    Energy investments imply changes in the physical, social, and economic environment. Hence, both the short-term and the long-term costs and benefits of these investments must be taken into account. These changes may affect not only the immediate environment of the investment site but may extend geographically far beyond national borders as well as beyond the lifetimes of the people for whom the investments are intended. This paper reviews the issues relevant to developing countries. General conceptual and policies issues are discussed. Issues about the measurement of costs and benefits (including issues of 'sustainability' and the internalization of externalities resulting from environmental changes) as well as the role of opportunity costs in deciding a country's energy investment strategies are raised. The macroeconomic and institutional issues relevant to environmental impacts that might be incorporated in energy planning are suggested. The paper is based on a presentation to the 'Workshop on energy investments and the environment'. 24 refs., 1 fig.

  5. Several key issues on implementing delay line based TDCs using FPGAs

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Jinyuan; /Fermilab

    2009-12-01

    Several topics in FPGA delay line based TDCs are discussed in this document. First, FPGA specific issues such as considerations on the delay line choice in different FPGA families, Wave Union Launchers, 'bubble proof' encoding logic, etc. are examined. Next, common problems for both FPGA TDCs and ASIC TDCs such as schemes of coarse time counter implementation, bin-by-bin calibration and noise issues due to single ended signals are discussed. Several resource/power saving design approaches for various processing stages are described in the document.

  6. Key issues of public relations of Europe: findings from the European Communication Monitor 2007-2014

    NARCIS (Netherlands)

    Verčič, D.; Verhoeven, P.; Zerfass, A.

    2014-01-01

    European Communication Monitor is the largest longitudinal research project in public relations practice in the world. Data collected annually from 2007 to 2014 show that practitioners perceive five issues as the most important for their work: linking business strategy and communication, coping with

  7. Can Competency-Based Training Fly?: An Overview of Key Issues for "Ab Initio" Pilot Training

    Science.gov (United States)

    Franks, Peter; Hay, Stephen; Mavin, Tim

    2014-01-01

    Competency-based training (CBT) for pilots was formally introduced in 1999 by the Civil Aviation Safety Authority (CASA) for training leading to the issue of aeroplane private and commercial pilot licences. This initiative followed the Australian government's introduction of CBT policy for vocational and workplace training in the late 1980's.…

  8. Key Instructional Design Issues in a Cellular Phone-Based Mobile Learning Project

    Science.gov (United States)

    Gedik, Nuray; Hanci-Karademirci, Arzu; Kursun, Engin; Cagiltay, Kursat

    2012-01-01

    Adding flexibility to the learning process, mobile learning offers great opportunities for education, especially for teenagers, who show great attentiveness to mobile technologies. Thus, the need to focus on design aspects of such learning is growing. This study aims to reveal critical issues in designing mobile learning based on a program for…

  9. What Do People Know about Key Environmental Issues? A Review of Environmental Knowledge Surveys

    Science.gov (United States)

    Robelia, Beth; Murphy, Tony

    2012-01-01

    This paper presents results from 15 little publicized state and national environmental surveys in the US that used similar questions. Our analysis reveals trends in adult understanding of environmental issues. These trends indicate that many may have difficulty making informed decisions about environmental policy as citizens, voters, and…

  10. Producer responsibility for e-waste management: key issues for consideration - learning from the Swiss experience.

    Science.gov (United States)

    Khetriwal, Deepali Sinha; Kraeuchi, Philipp; Widmer, Rolf

    2009-01-01

    E-waste, a relatively recent addition to the waste stream in the form of discarded electronic and electric equipment, is getting increasing attention from policy makers as the quantity being generated is rising rapidly. One of the most promising policy options to address this issue is to extend the producers responsibility for their products beyond the point of sale, until end-of-product-life. This paper briefly introduces the concept of extended producer responsibility (EPR) and its applicability in the area of the end-of-life management of electronic and electrical equipment (EEE). It then examines the decade-long experience of Switzerland in using EPR to manage its e-waste, elaborating on the experience of the Swiss system in overcoming specific issues, and finally wrapping up with a synopsis of the lessons for policy makers. We consider each issue as an enquiry of questions confronting a policy maker and the choices that may present themselves. The five issues discussed are: (i) the challenges in getting an EPR based system started; (ii) securing financing to ensure a self-sustaining and smooth functioning system; (iii) organising a logistics network for the take back and collection of the e-waste; (iv) ensuring compliance of the various actors involved; and finally (v) reducing the threat of monopolistic practices.

  11. The Development of Resources of Students in Adolescence as a Key Issue in Contemporary Education

    Science.gov (United States)

    Gosk, Urszula; Kuracki, Kamil

    2015-01-01

    In the presented paper, the issue of recognition and building of resources in adolescent pupils was discussed, referring to salutogenic concept of A. Antonovsky and Conservation of Resources Theory of S. E. Hobfoll. Coming out from developmental pedagogy and positive orientation in social sciences, benefits of scientific and educational actions…

  12. Leadership in Organizations: Current issues and key trends (3rd edition)

    OpenAIRE

    2016-01-01

    This is the third edition of a popular text first published in 2004. The 14 chapters locate the leadership phenomenon in the wider social and economic context. As the title suggests the underlying emphasis is upon changes to the understanding of leadership with reference to trends and current issues.

  13. Salt II: Toward Security or Danger? A Balanced Account of the Key Issues in the Debate.

    Science.gov (United States)

    Irwin, Wallace, Jr., Ed.; And Others

    Facts and controversial issues concerning SALT II (Strategic Arms Limitations Talks) are examined. The intent of the document is to enable non-specialists in military/strategic matters to arrive at their own conclusions. Central questions explored are: Is it possible to arrive at an agreement that will stabilize strategic arms competition and…

  14. The Causes of Poverty: Thinking Critically about a Key Economic Issue

    Science.gov (United States)

    Otlin, Josh

    2008-01-01

    Economics is a central part of civic education. Students need to know about the Constitution and the party system, but active citizenship in the twenty-first century requires much more than the standard civics courses offer. Economic issues dominate public policy debates ranging from Social Security to immigration to international security. If…

  15. EFFICIENT OFFICIAL STATISTICS AS A KEY TO THE ISSUE OF POST-CRISIS DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    N. I. Pashintseva

    2010-06-01

    Full Text Available Measures implemented by the Federal State Statistics Service aimed at regular monitoring of the situation in the territory of the Russian Federation have been considered in the paper. Issues related to unemployment and investment activity by enterprises in the context of the financial and economic crisis have been analyzed.

  16. Key issues in European food science research: a review of the European Food Science Day 2009

    NARCIS (Netherlands)

    Spichtinger, D.; Pongratz, I.; Jonsson, J.; Braun, S.; Colmer, C.; Poms, R.; Smith, R.; Ashwell, M.; Demeneix, B.; Skerfving, S.; Poel, van der W.H.M.; Laag, van der P.; Kuck, M.; Warkup, C.

    2010-01-01

    This paper is a report on the European Food Science Day (Brussels, 18 November 2009, organized by the CommNet network of food science communicators) and its outcomes. The article presents FP 7 as a key funding mechanism in European food and nutrition research and it puts research in this sector in a

  17. The Key Factors Affecting Grade 5 Achievement in Laos: Emerging Policy Issues

    Science.gov (United States)

    Hungi, Njora; Postlethwaite, Neville T.

    2009-01-01

    In this study, the authors employed a multilevel analysis procedure to examine the key pupil- and school-level factors that influenced reading and mathematics achievement among Grade 5 primary school pupils in Laos. The data for this study were collected in 2007 as part of a major project (known as Laos Grade 5 Survey) that sought to examine the…

  18. Habitability during long-duration space missions - Key issues associated with a mission to Mars

    Science.gov (United States)

    Stuster, Jack

    1989-01-01

    Isolation and confinement conditions similar to those of a long-duration mission to Mars are examined, focusing on 14 behavioral issues with design implications. Consideration is given to sleep, clothing, exercise, medical support, personal hygiene, food preparation, group interaction, habitat aesthetics, outside communications, recreational opportunities, privacy, waste disposal, onboard training, and the microgravity environment. The results are used to develop operational requirements and habitability design guidelines for interplanetary spacecraft.

  19. Cooperatives in a Global Economy: Key Economic Issues, Recent Trends, and Potential for Development

    OpenAIRE

    Smith, Stephen C; Rothbaum, Jonathan

    2013-01-01

    In this paper, we examine major trends and potential for cooperatives in the context of four prominent socio-economic issues: the lack of jobs, economic and social inequality, educational mobility, and the priority need for innovations. We present recent data on the amount and types of job creation in cooperatives. We consider co-ops in light of the recent financial and economic crises. Finally, we offer some observations on cooperatives and innovation, and some perspectives on the outlook go...

  20. Computer-Managed Instruction: Theory, Application, and Some Key Implementation Issues.

    Science.gov (United States)

    1984-03-01

    Orlando, Florida, May 10-14, 1982. k 118 89. Fullan , Michael and Park, Paul, "Curriculum Implementation," Ontario Ministry of Education, 1981. 90...ISSUES by 0 Michael Korbak, Jr. March 1984 LUL-4_ Thesis Advisor: Norman R. Lyons 1 Approved for public release; distribution unlimited S 10 10 044... Michael Korbak, Jr. S. PERFORMING ORGANIZATION NAME AND ADDRESS 0. PROGRAM ELEMENT. PROJECT. TASK AREA & WORK UNIT NUMBERS Naval Postgraduate School

  1. Key Issues in Central America Health Reforms : Diagnosis and Strategic Implications, Volume 2. Main Report

    OpenAIRE

    World Bank

    2007-01-01

    The main objective of this report is to identify and analyze the most pressing health sector issues in the sub region of El Salvador, Guatemala, Honduras, and Nicaragua (referred to as CA4) while building on the successes already attained, in order to lay the groundwork for discussing and refining strategies and policies in CA4. It will focus on analyzing (a) CA4 health sector performance,...

  2. Key Issues in Central America Health Reforms : Diagnosis and Strategic Implications, Volume 1. Synthesis of Findings

    OpenAIRE

    World Bank

    2007-01-01

    The main objective of this report is to identify and analyze the most pressing health sector issues in the sub region of El Salvador, Guatemala, Honduras, and Nicaragua (referred to as CA4) while building on the successes already attained, in order to lay the groundwork for discussing and refining strategies and policies in CA4. It will focus on analyzing (a) CA4 health sector performance,...

  3. Identifying the key issues focusing on the costs and benefits of immigration in developed countries

    OpenAIRE

    Dobra, Alexandra

    2009-01-01

    The present paper aims to acquaint concisely about the main issues surrounding the theme immigration, founded in the literature. This acquaintance is ensured through first (comprising the third part of the corpus), an overall focus on the question of assessing, on the one hand the benefits and on the other hand the costs of immigration, through the exploitation of many theories and arguments – especially concentrated on the economic and fiscal aspects - each being illustrated with specific ex...

  4. Foreign Affairs, Defense, and Trade: Key Issues for the 109th Congress

    Science.gov (United States)

    2004-12-27

    Training (IMET) program; Saudis have paid for all equipment they have acquired from the United States for many years. The U.S.-Saudi relationship and...program and associated investigations; allegations of sexual exploitation and abuse by members of U.N. peacekeeping forces CRS-23 and missions; the...others may advocate continued caution on the issue. Achieving the appropriate balance between treatment and prevention programs, including premarital

  5. Fatca and its key provisions and the issues of its application in Peru

    Directory of Open Access Journals (Sweden)

    Karen Sheppard Castillo

    2014-07-01

    Full Text Available As an answer to the international tax evasion problem, the U.S. Congress issued the Foreign Account Tax Compliance Act – Fatca. This Act aims to promote tax compliance among citizens and U.S. residents holding foreign bank accounts. To this effect, Fatca requires Foreign Financial Institutions to enter into an agreement with the Internal Revenue Service (IRS to provide the IRS information about the identity and the status of the bank accounts held by US persons. Entities not willing to enter into an agreement with the IRS will be subject to a 30% withholding on U.S. sourced income regardless of whether the income is tax exempt. The application of this Act in our country brings a lot of concern regarding some issues, such us extraterritoriality, bank secrecy, the application of civil and criminal law. Since the effective date of implementation of Fatca is July 1, 2014, we understand that an official opinion concerning these issues and the possibilityto enter into an Intergovernmental Agreement with the U.S. government will be forthcoming in the following months.

  6. Patient safety and interprofessional education: A report of key issues from two interprofessional workshops.

    Science.gov (United States)

    Anderson, Elizabeth S; Gray, Richard; Price, Kim

    2017-03-01

    This article presents the outcomes of two workshops which explored historical and recent issues on patient safety that directly relate to leaders in the interprofessional field. The article considers the impact of flattened team-based structures where collaborative working constantly considers safe patient-centred high-quality care. These issues are mainly rooted in changes within a UK context, but the historical case studies present situations which could enlighten and enliven discussions of patient safety in an international context. The article was sparked by discussion of recurrent themes in healthcare that have undermined the abilities of medical practitioners to adequately manage hazard in clinical care settings throughout modern history. Examining the issues that confront healthcare practitioners and care workers in their dealings with patients and clients, such as the aged or the severely disabled, can reveal commonalities across global healthcare settings, in the past and present, that provide a useful tool in facilitating the goals of interprofessional education (IPE). The potential of IPE has links to both how professionals respond together to care situations and involve the general public in shared health understandings. The outcomes focus on how to ensure ministrations where optimal team-based collaborative care is recognised and constantly sought. We conclude that IPE has much to offer in this arena and more evidence of impact here is well worth pursuing.

  7. Network theory: key issues for the analysis of the "brain drain"

    Directory of Open Access Journals (Sweden)

    Diana Carolina Henao

    2012-12-01

    Full Text Available This paper offers an analysis of the brain drain from the perspective of the network theory. Some definitions and key concepts of the network theory have been discussed in relation to criteria and reasons that are taken into account by people with broad educational capital from developing countries who are involved in the research in different areas of knowledge and who seek to adapt to other scientific collaboration networks in the developed countries.

  8. Quantum mechanics of excitation transport in photosynthetic complexes: a key issues review.

    Science.gov (United States)

    Levi, Federico; Mostarda, Stefano; Rao, Francesco; Mintert, Florian

    2015-07-01

    For a long time microscopic physical descriptions of biological processes have been based on quantum mechanical concepts and tools, and routinely employed by chemical physicists and quantum chemists. However, the last ten years have witnessed new developments on these studies from a different perspective, rooted in the framework of quantum information theory. The process that more, than others, has been subject of intense research is the transfer of excitation energy in photosynthetic light-harvesting complexes, a consequence of the unexpected experimental discovery of oscillating signals in such highly noisy systems. The fundamental interdisciplinary nature of this research makes it extremely fascinating, but can also constitute an obstacle to its advance. Here in this review our objective is to provide an essential summary of the progress made in the theoretical description of excitation energy dynamics in photosynthetic systems from a quantum mechanical perspective, with the goal of unifying the language employed by the different communities. This is initially realized through a stepwise presentation of the fundamental building blocks used to model excitation transfer, including protein dynamics and the theory of open quantum system. Afterwards, we shall review how these models have evolved as a consequence of experimental discoveries; this will lead us to present the numerical techniques that have been introduced to quantitatively describe photo-absorbed energy dynamics. Finally, we shall discuss which mechanisms have been proposed to explain the unusual coherent nature of excitation transport and what insights have been gathered so far on the potential functional role of such quantum features.

  9. Quantum mechanics of excitation transport in photosynthetic complexes: a key issues review

    Science.gov (United States)

    Levi, Federico; Mostarda, Stefano; Rao, Francesco; Mintert, Florian

    2015-07-01

    For a long time microscopic physical descriptions of biological processes have been based on quantum mechanical concepts and tools, and routinely employed by chemical physicists and quantum chemists. However, the last ten years have witnessed new developments on these studies from a different perspective, rooted in the framework of quantum information theory. The process that more, than others, has been subject of intense research is the transfer of excitation energy in photosynthetic light-harvesting complexes, a consequence of the unexpected experimental discovery of oscillating signals in such highly noisy systems. The fundamental interdisciplinary nature of this research makes it extremely fascinating, but can also constitute an obstacle to its advance. Here in this review our objective is to provide an essential summary of the progress made in the theoretical description of excitation energy dynamics in photosynthetic systems from a quantum mechanical perspective, with the goal of unifying the language employed by the different communities. This is initially realized through a stepwise presentation of the fundamental building blocks used to model excitation transfer, including protein dynamics and the theory of open quantum system. Afterwards, we shall review how these models have evolved as a consequence of experimental discoveries; this will lead us to present the numerical techniques that have been introduced to quantitatively describe photo-absorbed energy dynamics. Finally, we shall discuss which mechanisms have been proposed to explain the unusual coherent nature of excitation transport and what insights have been gathered so far on the potential functional role of such quantum features.

  10. Towards optimised information about clinical trials; identification and validation of key issues in collaboration with cancer patient advocates

    DEFF Research Database (Denmark)

    Dellson, P; Nilbert, M; Bendahl, P-O

    2011-01-01

    in three clinical trials for breast cancer. Primary data collection was done in focus group interviews with breast cancer patient advocates. Content analysis identified three major themes: comprehensibility, emotions and associations, and decision making. Based on the advocates' suggestions...... for improvements, 21 key issues were defined and validated through a questionnaire in an independent group of breast cancer patient advocates. Clear messages, emotionally neutral expressions, careful descriptions of side effects, clear comparisons between different treatment alternatives and information about...

  11. Recent hydrocarbon developments in Latin America: Key issues in the downstream oil sector

    Energy Technology Data Exchange (ETDEWEB)

    Wu, K.; Pezeshki, S.

    1995-03-01

    This report discusses the following: (1) An overview of major issues in the downstream oil sector, including oil demand and product export availability, the changing product consumption pattern, and refineries being due for major investment; (2) Recent upstream developments in the oil and gas sector in Argentina, Bolivia, Brazil, Chile, Colombia, Ecuador, Mexico, Peru, Trinidad and Tobago, and Venezuela; (3) Recent downstream developments in the oil and gas sector in Argentina, Chile, Colombia, Ecuador, Mexico, Peru, Cuba, and Venezuela; (4) Pipelines in Argentina, Bolivia, Brazil, Chile, and Mexico; and (5) Regional energy balance. 4 figs., 5 tabs.

  12. The Development of Resources of Students in Adolescence as a Key Issue in Contemporary Education

    Directory of Open Access Journals (Sweden)

    Gosk Urszula

    2015-08-01

    Full Text Available In the presented paper, the issue of recognition and building of resources in adolescent pupils was discussed, referring to salutogenic concept of A. Antonovsky and Conservation of Resources Theory of S. E. Hobfoll. Coming out from developmental pedagogy and positive orientation in social sciences, benefits of scientific and educational actions concentrated on identifying pupils’ resources and supporting them in generating them, were shown. On the basis of Polish and foreign literature, empirical research treating about pupils’ resource, was analyzed, with special attention put to the sense of coherence and its components, stress management and behavior fostering health.

  13. Atomically Flat Surface: The Key Issue for Solution-Derived Epitaxial Multilayers

    Science.gov (United States)

    Coll, Mariona; Pomar, Alberto; Puig, Teresa; Obradors, Xavier

    2008-12-01

    We present a general methodology to study the morphology of complex thin film surfaces by evaluating the percentage of flat area through the use of atomic force microscopy. We prove that this is the key parameter to assess the suitability of a layer and ensure the desired epitaxy of the subsequent layer in a heterostructure. The method has been verified by applying it to chemically deposited YBa2Cu3O7 (YBCO) superconducting films grown on buffer layers with different surface morphologies. We demonstrate that, indeed, YBCO self-field critical current density is controlled by the buffer layer flat area fraction.

  14. Key science issues after MESSENGER and current observation plans of BepiColombo MMO

    Science.gov (United States)

    Murakami, Go; Hayakawa, Hajime; Fujimoto, Masaki

    2017-04-01

    Little had been known about the Hermean magnetosphere until MESSENGER explored the region. The region is formed as the weak planetary magnetic field stands against the intense solar wind in the close proximity of the Sun. Various prediction had been given by noting the difference in the parameters from the well-studied terrestiral magnetosphere of a similar setting and scaling the well-knowns to the Hermean environment. MESSENGER results, however, show a wide varieity of phenomena that are out of the scope of what one could have reasonably argued. The micro-magnetosphere of Mercury is much more dynamic than one had predicted. BepiColombo MMO, the JAXA spacecraft of the BepiColombo Mercury exploration mission which will be launched in 2018 and will arrive at Mercury in 2025, is equipped to study the space environment of the planet Mercury. BepiColombo MMO is mainly designed for plasma observations and is expected to extract essential elements of space plasma physics that become visible in the Hermean environment. MMO has large constraints on science operations, such as thermal issue and limited telemetry rate. Due to the thermal issue each science instrument cannot always be turned on. In addition, due to the low telemetry rate in average, only a part ( 20-30%) of science mission data with high resolution can be downlinked. Therefore, in order to maximize the scientific results and outcomes to be achieved by MMO, we are now working to optimize the science observation and downlink plans in detail. Here we review MESSENGER results and how MMO will contribute to deepen our understanding of space plasmas by addressing the puzzles raised by MESSEGNER.

  15. Non-equilibrium physics and evolution--adaptation, extinction, and ecology: a key issues review.

    Science.gov (United States)

    Kussell, E; Vucelja, M

    2014-10-01

    Evolutionary dynamics in nature constitute an immensely complex non-equilibrium process. We review the application of physical models of evolution, by focusing on adaptation, extinction, and ecology. In each case, we examine key concepts by working through examples. Adaptation is discussed in the context of bacterial evolution, with a view toward the relationship between growth rates, mutation rates, selection strength, and environmental changes. Extinction dynamics for an isolated population are reviewed, with emphasis on the relation between timescales of extinction, population size, and temporally correlated noise. Ecological models are discussed by focusing on the effect of spatial interspecies interactions on diversity. Connections between physical processes--such as diffusion, turbulence, and localization--and evolutionary phenomena are highlighted.

  16. On the path to sustainability: Key issues on Nigeria’s sustainable energy development

    Directory of Open Access Journals (Sweden)

    Norbert Edomah

    2016-11-01

    Full Text Available In the face of scarcity of energy resources and rising energy prices due primarily to a world of increasing demand, energy security concerns becomes more crucial both for private and public sector alike. At the same time, energy policies have been shifting and policy changes have become hard to predict because of radical changes in energy supply. This paper analyzes the barriers to sustainable energy development in Nigeria which are: (1 cost and pricing barriers, (2 legal and regulatory barriers, (3 market performance barriers. It concludes by highlighting some key policies that can help address some of the identified barriers in order to ensure a secured sustainable energy future for Nigeria.

  17. Key Data Gaps Regarding the Public Health Issues Associated with Opioid Analgesics.

    Science.gov (United States)

    Schmidt, Teresa D; Haddox, J David; Nielsen, Alexandra E; Wakeland, Wayne; Fitzgerald, John

    2015-10-01

    Most pharmaceutical opioids are used to treat pain, and they have been demonstrated to be effective medications for many. Their abuse and misuse pose significant public health concerns in the USA. Research has provided much insight into the prevalence, scope, and drivers of opioid abuse, but a holistic understanding is limited by a lack of available data regarding key aspects of this public health problem. Twelve data gaps were revealed during the creation of a systems-level computer model of medical use, diversion, nonmedical use, and the adverse outcomes associated with opioid analgesics in the USA. Data specific to these gaps would enhance the validity and real-world applications of systems-level models of this public health problem and would increase understanding of the complex system in which use and abuse occur. This paper provides an overview of these gaps, argues for the importance of closing them, and provides specific recommendations for future data collection efforts.

  18. Information processing in bacteria: memory, computation, and statistical physics: a key issues review

    Science.gov (United States)

    Lan, Ganhui; Tu, Yuhai

    2016-05-01

    Living systems have to constantly sense their external environment and adjust their internal state in order to survive and reproduce. Biological systems, from as complex as the brain to a single E. coli cell, have to process these data in order to make appropriate decisions. How do biological systems sense external signals? How do they process the information? How do they respond to signals? Through years of intense study by biologists, many key molecular players and their interactions have been identified in different biological machineries that carry out these signaling functions. However, an integrated, quantitative understanding of the whole system is still lacking for most cellular signaling pathways, not to say the more complicated neural circuits. To study signaling processes in biology, the key thing to measure is the input-output relationship. The input is the signal itself, such as chemical concentration, external temperature, light (intensity and frequency), and more complex signals such as the face of a cat. The output can be protein conformational changes and covalent modifications (phosphorylation, methylation, etc), gene expression, cell growth and motility, as well as more complex output such as neuron firing patterns and behaviors of higher animals. Due to the inherent noise in biological systems, the measured input-output dependence is often noisy. These noisy data can be analysed by using powerful tools and concepts from information theory such as mutual information, channel capacity, and the maximum entropy hypothesis. This information theory approach has been successfully used to reveal the underlying correlations between key components of biological networks, to set bounds for network performance, and to understand possible network architecture in generating observed correlations. Although the information theory approach provides a general tool in analysing noisy biological data and may be used to suggest possible network architectures in

  19. Resources for our Future. Key issues and best practices in resource efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Weterings, R.; Bastein, T.; Tukker, A. [TNO, Delft (Netherlands); Rademaker, M.; De Ridder, M. [The Hague Centre for Strategic studies HCSS, Den Haag (Netherlands)

    2013-08-15

    This book provides an analysis of the issues surrounding international resources and inspiring accounts of industrial best practices. The book consists of two distinct parts. The first part of the book brings together the results of years of research into the geopolitical, economic and ecological dimensions of material scarcity and resource efficiency. Chapter 2 discusses the main challenges and constraints related to the use of energy resources, water and land, industrial and metallic minerals, construction minerals and biotic resources, including water use and ecosystem degradation. The chapter also addresses important linkages between these various resources. Chapter 3 describes the international trends that are shaping the geopolitics of natural resources and looks at the implications for Europe and the Netherlands. Chapter 4 presents a wide range of strategies by which governments, producers and consumers may contribute to the more sustainable use of natural resources. The second part of the book describes 21 inspiring best practices in resource efficiency in a variety of industrial sectors. Based on a series of interviews with industrial pioneers, these chapters relate their first-hand experiences in improving resource efficiency. These business cases demonstrate that innovation and entrepreneurship can result in substantial improvements in resource efficiency. Chapter 5 focuses on best practices in the built environment, where substantial amounts of energy and minerals are used. Chapter 6 presents four ambitious strategies to promote sustainable food production and consumption. Chapter 7 describes recent developments in the chemical process industry, which produces most of the ingredients, compounds and semi-products for the vast range of products used by society. Chapter 8 provides four examples of the state-of-the-art in resource efficiency in the metal and high-tech industries. This chapter presents four business cases highlighting the benefits of the

  20. The crisis in access to essential medicines in India: key issues which call for action.

    Science.gov (United States)

    Bhargava, Anurag; Kalantri, S P

    2013-01-01

    The government is planning to introduce free generic and essential medicines in public health facilities. Most people in India buy healthcare from the private sector, a compulsion that accounts for a high proportion of healthcare-related expenditure. To reduce the burden of healthcare costs, the government must improve availability and affordability of generic and essential medicines in the market. It can do so because India's large pharmaceutical industry is a major source of generic medicines worldwide. In this article, we discuss three factors that have impeded access to generic and essential medicines: (1) mistaken notions among policymakers, prescribers and patients about branded drugs and generic drugs in India; (2) high prices of medicines due to the progressive dismantling of the system of regulation of medicine prices, and (3) a drug approval and regulatory system that allows medicines (including fixed dose combinations) of doubtful efficacy, rationale, safety and public health relevance to dominate the market at the cost of access to affordable generic and essential medicines. The consequences of ill-health and wasted expenditure on drugs raise issues of public health ethics.Improving access to essential medicines in India is an urgent public health and ethical imperative. This should include improved public provisioning, a system of regulation of drug prices, and an evidence-based drug approval process.

  1. Birds of the Severn Estuary and Bristol Channel: their current status and key environmental issues.

    Science.gov (United States)

    Burton, N H K; Musgrove, A J; Rehfisch, M M; Clark, N A

    2010-01-01

    The Severn Estuary and Bristol Channel encompass a number of designated sites supporting populations of waterbirds and seabirds that are of national or international importance, including the Severn Estuary and Burry Inlet Special Protection Areas (SPAs)/Ramsar Sites and Carmarthen Bay, the UK's first marine SPA. Here, we provide an overview of the present numbers and trends of the waterbirds and seabirds using these sites, updating previous reviews undertaken prior to these designations. We further provide a summary of the main issues that have affected the status of the area's bird populations. Declines in the numbers of waders on the Severn Estuary and the southwest over the last two decades have been linked to climate change. The Sea Empress oil-spill impacted both breeding seabirds and the wintering Common Scoters in Carmarthen Bay, though numbers of the latter recovered 3years after the spill. At the Burry Inlet, Oystercatcher numbers have fallen over the last 25years and considerable research has been undertaken into the conflict with cockle and mussel fisheries. A long-term study at Cardiff Bay, at the mouth of the Severn, revealed a significant impact on the survival of Redshanks following its impoundment and has helped to further understanding of responses of waterbirds to estuarine habitat loss. The potential impacts of the construction of a tidal power scheme on the Severn Estuary are also discussed. (c) 2009 Elsevier Ltd. All rights reserved.

  2. Gastrostomy tube feeding in children with epidermolysis bullosa: consideration of key issues.

    Science.gov (United States)

    Haynes, Lesley; Mellerio, Jemima E; Martinez, Anna E

    2012-01-01

    Complications of severe forms of epidermolysis bullosa (EB) almost invariably lead to chronic malnutrition, jeopardizing immune status, growth, iron status, bone health, wound healing, and quality of life. Although gastrostomy tube (G-tube) feeding has successfully addressed the difficulties of providing nutrition and medications in some children attending our center, others have developed problems such as abdominal distension, poor feed tolerance, and leakage of gastric contents with persistent localized skin ulceration, posing enormous challenges to skin management and nutritional maintenance. Suspicions that G-tube placement and feeding cause or exacerbate these problems has led to a decline in placements at our center over the last 10 years. We therefore recognized that it should not be rejected without due consideration of why some patients seem more prone to complications than others. Thus, information on selected issues and outcomes of G-tube placement was obtained from records of 66 patients undergoing surgery between 1989 and 2008. The complex interrelationships of the sequelae of severe EB, changes in practice over 20 years and lack of data for patients treated early in the series make it impossible to draw firm conclusions at this stage, however, our scrutiny provides valuable information on which to base debate and future studies. It also offers well as useful insights for fellow professionals involved in nutrition support in children with severe EB. © 2012 Wiley Periodicals, Inc.

  3. Rising food costs & global food security: Key issues & relevance for India

    Directory of Open Access Journals (Sweden)

    Daniel J Gustafson

    2013-01-01

    Full Text Available Rising food costs can have major impact on vulnerable households, pushing those least able to cope further into poverty and hunger. On the other hand, provided appropriate policies and infrastructure are in place, higher agricultural prices can also raise farmers′ incomes and rural wages, improve rural economies and stimulate investment for longer-term economic growth. High food prices since 2007 have had both short-term impacts and long-term consequences, both good and bad. This article reviews the evidence of how rising costs have affected global food security since the food price crisis of 2007-2008, and their impact on different categories of households and countries. In light of recent studies, we know more about how households, and countries, cope or not with food price shocks but a number of contentious issues remain. These include the adequacy of current estimates and the interpretation of national and household food and nutrition security indicators. India is a particularly important country in this regard, given the high number of food insecure, the relative weight of India in global estimates of food and nutrition insecurity, and the puzzles that remain concerning the country′s reported declining per capita calorie consumption. Competing explanations for what is behind it are not in agreement, but these all point to the importance of policy and programme innovation and greater investment necessary to reach the achievable goal of food and nutrition security for all.

  4. A Review on Key Issues and Challenges in Devices Level MEMS Testing

    Directory of Open Access Journals (Sweden)

    Muhammad Shoaib

    2016-01-01

    Full Text Available The present review provides information relevant to issues and challenges in MEMS testing techniques that are implemented to analyze the microelectromechanical systems (MEMS behavior for specific application and operating conditions. MEMS devices are more complex and extremely diverse due to the immersion of multidomains. Their failure modes are distinctive under different circumstances. Therefore, testing of these systems at device level as well as at mass production level, that is, parallel testing, is becoming very challenging as compared to the IC test, because MEMS respond to electrical, physical, chemical, and optical stimuli. Currently, test systems developed for MEMS devices have to be customized due to their nondeterministic behavior and complexity. The accurate measurement of test systems for MEMS is difficult to quantify in the production phase. The complexity of the device to be tested required maturity in the test technique which increases the cost of test development; this practice is directly imposed on the device cost. This factor causes a delay in time-to-market.

  5. Parenting gifted and talented children: what are the key child behaviour and parenting issues?

    Science.gov (United States)

    Morawska, Alina; Sanders, Matthew R

    2008-09-01

    The literature on gifted and talented children is limited. Little is known about the types and nature of difficulties experienced by gifted and talented children, and even less known about parenting issues related to parenting a gifted and talented child. The aim of the present study was to describe children's behavioural and emotional adjustment, and the factors that contribute to children's difficulties, as well as to examine the styles of discipline used by parents of gifted and talented children and their level of confidence in managing specific parenting tasks. A survey of parents of gifted and talented children was conducted, with 211 parents meeting criteria for the study. For a community sample, in general gifted and talented children exhibit no more behavioural difficulties than do other children. But children in this sample seemed to show higher levels of emotional symptoms and peer problems. Children's behavioural and emotional difficulties were best predicted by parenting factors, particularly parental confidence. Parents reported that they were less likely to be permissive with their child, but they tended to use a more authoritarian style of parenting characterized by lecturing and a strong reaction to any problems. There are a number of implications for future research, clinical practice, and the development of parenting interventions for this group of parents.

  6. Rising food costs & global food security: key issues & relevance for India.

    Science.gov (United States)

    Gustafson, Daniel J

    2013-09-01

    Rising food costs can have major impact on vulnerable households, pushing those least able to cope further into poverty and hunger. On the other hand, provided appropriate policies and infrastructure are in place, higher agricultural prices can also raise farmers' incomes and rural wages, improve rural economies and stimulate investment for longer-term economic growth. High food prices since 2007 have had both short-term impacts and long-term consequences, both good and bad. This article reviews the evidence of how rising costs have affected global food security since the food price crisis of 2007-2008, and their impact on different categories of households and countries. In light of recent studies, we know more about how households, and countries, cope or not with food price shocks but a number of contentious issues remain. These include the adequacy of current estimates and the interpretation of national and household food and nutrition security indicators. India is a particularly important country in this regard, given the high number of food insecure, the relative weight of India in global estimates of food and nutrition insecurity, and the puzzles that remain concerning the country's reported declining per capita calorie consumption. Competing explanations for what is behind it are not in agreement, but these all point to the importance of policy and programme innovation and greater investment necessary to reach the achievable goal of food and nutrition security for all.

  7. Origins of life: a problem for physics, a key issues review.

    Science.gov (United States)

    Walker, Sara Imari

    2017-09-01

    The origins of life stands among the great open scientific questions of our time. While a number of proposals exist for possible starting points in the pathway from non-living to living matter, these have so far not achieved states of complexity that are anywhere near that of even the simplest living systems. A key challenge is identifying the properties of living matter that might distinguish living and non-living physical systems such that we might build new life in the lab. This review is geared towards covering major viewpoints on the origin of life for those new to the origin of life field, with a forward look towards considering what it might take for a physical theory that universally explains the phenomenon of life to arise from the seemingly disconnected array of ideas proposed thus far. The hope is that a theory akin to our other theories in fundamental physics might one day emerge to explain the phenomenon of life, and in turn finally permit solving its origins.

  8. Origins of life: a problem for physics, a key issues review

    Science.gov (United States)

    Imari Walker, Sara

    2017-09-01

    The origins of life stands among the great open scientific questions of our time. While a number of proposals exist for possible starting points in the pathway from non-living to living matter, these have so far not achieved states of complexity that are anywhere near that of even the simplest living systems. A key challenge is identifying the properties of living matter that might distinguish living and non-living physical systems such that we might build new life in the lab. This review is geared towards covering major viewpoints on the origin of life for those new to the origin of life field, with a forward look towards considering what it might take for a physical theory that universally explains the phenomenon of life to arise from the seemingly disconnected array of ideas proposed thus far. The hope is that a theory akin to our other theories in fundamental physics might one day emerge to explain the phenomenon of life, and in turn finally permit solving its origins.

  9. Analysis of the key issues in establishing the Russian-based high technological companies

    Directory of Open Access Journals (Sweden)

    V. G. Zinov

    2016-01-01

    Full Text Available The article analyses the reasons that prevent a competitive export-oriented Russian domestic development of the robot surgical complex from being industrially prototyped and serially released for the domestic and global market. The development is completed within the framework of a «priority project» which was also highlighted as of significant importance in the Forecast analysis of the scientific-technological development of Russia for the period of up until 2030 and in the road maps of the National technological initiative and other strategic documents. The project was financed by nearly all development funds and institutes in Russia. A conclusion is drawn that the key reason behind the significant increase in a life span of a high-tech market product is the absence of a target setting and a programme of coordinated actions from committed ministries and governmental agencies, as well as the lack of a large high tech company in Russia, capable of producing in industrial volumes the export-oriented products and ensure their global sales.

  10. Key issues in estimating energy and greenhouse gas savings of biofuels: challenges and perspectives

    Directory of Open Access Journals (Sweden)

    Dheeraj Rathore

    2016-06-01

    Full Text Available The increasing demand for biofuels has encouraged the researchers and policy makers worldwide to find sustainable biofuel production systems in accordance with the regional conditions and needs. The sustainability of a biofuel production system includes energy and greenhouse gas (GHG saving along with environmental and social acceptability. Life cycle assessment (LCA is an internationally recognized tool for determining the sustainability of biofuels. LCA includes goal and scope, life cycle inventory, life cycle impact assessment, and interpretation as major steps. LCA results vary significantly, if there are any variations in performing these steps. For instance, biofuel producing feedstocks have different environmental values that lead to different GHG emission savings and energy balances. Similarly, land-use and land-use changes may overestimate biofuel sustainability. This study aims to examine various biofuel production systems for their GHG savings and energy balances, relative to conventional fossil fuels with an ambition to address the challenges and to offer future directions for LCA based biofuel studies. Environmental and social acceptability of biofuel production is the key factor in developing biofuel support policies. Higher GHG emission saving and energy balance of biofuel can be achieved, if biomass yield is high, and ecologically sustainable biomass or non-food biomass is converted into biofuel and used efficiently.

  11. The Water Risks of Hydraulic Fracturing (Fracking): Key Issues from the New California Assessment

    Science.gov (United States)

    Gleick, P. H.

    2015-12-01

    A key component of the Water-Energy Nexus is the effort over the past decade or so to quantify the volumes and form of water required for the energy fuel cycle from extraction to generation to waste disposal. The vast majority of the effort in this area has focused on the water needs of electricity generation, but other fuel-cycle components also entail significant water demands and threats to water quality. Recent work for the State of California (managed by the California Council on Science and Technology - CCST) has produced a new state-of-the-art assessment of a range of potential water risks associated with hydraulic fracturing and related oil and gas extraction, including volumetric water demands, methods of disposal of produced water, and aquifer contamination. For example, this assessment produced new information on the disposal of produced water in surface percolation pits and the potential for contamination of local groundwater (see Figure). Understanding these risks raises questions about current production and future plans to expand production, as well as tools used by state and federal agencies to manage these risks. This talk will summarize the science behind the CCST assessment and related policy recommendations for both water and energy managers.

  12. Herbal hepatotoxicity in traditional and modern medicine: actual key issues and new encouraging steps.

    Science.gov (United States)

    Teschke, Rolf; Eickhoff, Axel

    2015-01-01

    Plants are natural producers of chemical substances, providing potential treatment of human ailments since ancient times. Some herbal chemicals in medicinal plants of traditional and modern medicine carry the risk of herb induced liver injury (HILI) with a severe or potentially lethal clinical course, and the requirement of a liver transplant. Discontinuation of herbal use is mandatory in time when HILI is first suspected as diagnosis. Although, herbal hepatotoxicity is of utmost clinical and regulatory importance, lack of a stringent causality assessment remains a major issue for patients with suspected HILI, while this problem is best overcome by the use of the hepatotoxicity specific CIOMS (Council for International Organizations of Medical Sciences) scale and the evaluation of unintentional reexposure test results. Sixty five different commonly used herbs, herbal drugs, and herbal supplements and 111 different herbs or herbal mixtures of the traditional Chinese medicine (TCM) are reported causative for liver disease, with levels of causality proof that appear rarely conclusive. Encouraging steps in the field of herbal hepatotoxicity focus on introducing analytical methods that identify cases of intrinsic hepatotoxicity caused by pyrrolizidine alkaloids, and on omics technologies, including genomics, proteomics, metabolomics, and assessing circulating micro-RNA in the serum of some patients with intrinsic hepatotoxicity. It remains to be established whether these new technologies can identify idiosyncratic HILI cases. To enhance its globalization, herbal medicine should universally be marketed as herbal drugs under strict regulatory surveillance in analogy to regulatory approved chemical drugs, proving a positive risk/benefit profile by enforcing evidence based clinical trials and excellent herbal drug quality.

  13. Herbal hepatotoxicity in traditional and modern medicine: Actual key issues and new encouraging steps

    Directory of Open Access Journals (Sweden)

    Rolf eTeschke

    2015-04-01

    Full Text Available Plants are natural producers of chemical substances, providing potential treatment of human ailments since ancient times. Some herbal chemicals in medicinal plants of traditional and modern medicine carry the risk of herb induced liver injury (HILI with a severe or potentially lethal clinical course, and the requirement of a liver transplant. Discontinuation of herbal use is mandatory in time when HILI is first suspected as diagnosis. Although herbal hepatotoxicity is of utmost clinical and regulatory importance, lack of a stringent causality assessment remains a major issue for patients with suspected HILI, while this problem is best overcome by the use of the hepatotoxicity specific CIOMS (Council for International Organizations of Medical Sciences scale and the evaluation of unintentional reexposure test results. Sixty five different commonly used herbs, herbal drugs, and herbal supplements and 111 different herbs or herbal mixtures of the traditional Chinese medicine (TCM are reported causative for liver disease, with levels of causality proof that appear rarely conclusive. Encouraging steps in the field of herbal hepatotoxicity focus on introducing analytical methods that identify cases of intrinsic hepatotoxicity caused by pyrrolizidine alkaloids, and on omics technologies, including genomics, proteomics, metabolomics, and assessing circulating micro-RNA in the serum of some patients with intrinsic hepatotoxicity. It remains to be established whether these new technologies can identify idiosyncratic HILI cases. To enhance its globalization, herbal medicine should universally be marketed as herbal drugs under strict regulatory surveillance in analogy to regulatory approved chemical drugs, proving a positive risk/benefit profile by enforcing evidence based clinical trials and excellent herbal drug quality.

  14. Global trade, public health, and health services: stakeholders' constructions of the key issues.

    Science.gov (United States)

    Waitzkin, Howard; Jasso-Aguilar, Rebeca; Landwehr, Angela; Mountain, Carolyn

    2005-09-01

    Focusing mainly on the United States and Latin America, we aimed to identify the constructions of social reality held by the major stakeholders participating in policy debates about global trade, public health, and health services. In a multi-method, qualitative design, we used three sources of data: research and archival literature, 1980-2004; interviews with key informants who represented major organizations participating in these debates, 2002-2004; and organizational reports, 1980-2004. We targeted several types of organizations: government agencies, international financial institutions (IFIs) and trade organizations, international health organizations, multinational corporations, and advocacy groups. Many governments in Latin America define health as a right and health services as a public good. Thus, the government bears responsibility for that right. In contrast, the US government's philosophy of free trade and promoting a market economy assumes that by expanding the private sector, improved economic conditions will improve overall health with a minimum government provision of health care. US government agencies also view promotion of global health as a means to serve US interests. IFIs have emphasized reforms that include reduction and privatization of public sector services. International health organizations have tended to adopt the policy perspectives of IFIs and trade organizations. Advocacy groups have emphasized the deleterious effects of international trade agreements on public health and health services. Organizational stakeholders hold widely divergent constructions of reality regarding trade, public health, and health services. Social constructions concerning trade and health reflect broad ideologies concerning the impacts of market processes. Such constructions manifest features of "creed," regarding the role of the market in advancing human purposes and meeting human needs. Differences in constructions of trade and health constrain policies to

  15. Competency, confidence and conflicting evidence: key issues affecting health visitors' use of research evidence in practice

    Directory of Open Access Journals (Sweden)

    Calnan Michael

    2009-04-01

    Full Text Available Abstract Background Health visitors play a pivotal position in providing parents with up-to-date evidence-based care on child health. The recent controversy over the safety of the MMR vaccine has drawn attention to the difficulties they face when new research which raises doubts about current guidelines and practices is published. In the aftermath of the MMR controversy, this paper investigates the sources health visitors use to find out about new research evidence on immunisation and examines barriers and facilitators to using evidence in practice. It also assesses health visitors' confidence in using research evidence. Methods Health visitors were recruited from the 2007 UK Community Practitioners' and Health Visitors' Association conference. All delegates were eligible to complete the questionnaire if in their current professional role they advise parents about childhood immunisation or administer vaccines to children. Of 228 who were eligible, 185 completed the survey (81.1%. Results These health visitors used a wide range of resources to find out about new research evidence on childhood immunisation. Popular sources included information leaflets and publications, training days, nursing journals and networking with colleagues. A lack of time was cited as the main barrier to searching for new evidence. The most common reason given for not using research in practice was a perception of conflicting research evidence. Understanding the evidence was a key facilitator. Health visitors expressed less confidence about searching and explaining research on childhood immunisation than evidence on weaning and a baby's sleep position. Conclusion Even motivated health visitors feel they lack the time and, in some cases, the skills to locate and appraise research evidence. This research suggests that of the provision of already-appraised research would help to keep busy health professionals informed, up-to-date and confident in responding to public

  16. Tourism development in contemporary Central and Eastern Europe: Challenges for the industry and key issues for researchers

    Directory of Open Access Journals (Sweden)

    Derek R. Hall

    2011-11-01

    Full Text Available Within the context of tourism development in the countries of contemporary Central and Eastern Europe, this paper briefly discusses the challenges for industry and key issues for researchers within six broad topic areas. These are: climate change adaptation and mitigation; integration with sustainable development strategies; coping with globalization; differentiation/ uniqueness; innovation; and collaboration / partnership / networking. Practical cases are drawn from Western European experience to exemplify potential opportunities, and recent published research is identified to inform fruitful research directions. It is concluded that challenges and issues are similar across Europe, and that those relating to climate change adaptation and mitigation are, in the wider context, the most important to understand and address.

  17. The use of conversation mapping to frame key perceptual issues facing the general dental practice system in England.

    Science.gov (United States)

    Harris, R V; Dancer, J M; Smith, D; Campbell, S

    2009-06-01

    To demonstrate the use of a novel qualitative methodology namely conversation mapping, which can be used to capture differences in stakeholder perspectives and give a root definition of the problem in a complex policy area. The methodology is used in the context of the changes introduced in the English general dental practice system in April 2006, to investigate the key issues facing the system, as perceived by general dental practitioners (GDPs). From a broad trigger statement, three transformational statements were produced. Each participant recorded their contribution on a hard diagrammatic form as a 'map', with others responding with their own written comment, thus generating three conversation maps. Thematic analysis resulted in the generation of a preliminary model summarising key perceptual issues. The five emergent themes identified were: financing, dentists' wants/needs, the role of the public and patients, system goals and policy level decision making. Financing was identified as the core category to which all other categories were related. Conversation mapping, a methodology arising from a systems approach, can be used to develop a 'rich picture' of an oral health care system in order to define the core problem within this policy area. Findings suggest that GDPs identify the financing of the system as a fundamental source of problems within the general dental practice system. This appears to be at variance with the perception of policy makers, who report a more limited view, identifying the system of remuneration as the 'heart of the problem'.

  18. Key issues and challenges in developing a pedagogical intervention in the simulation skills center--an action research study.

    Science.gov (United States)

    Reierson, Inger Åse; Hvidsten, Anne; Wighus, Marianne; Brungot, Solvor; Bjørk, Ida Torunn

    2013-07-01

    Simulation skills centers (SSC) are considered important learning arenas for preparing and qualifying nursing students. Limited clinical placements and claims of diminished learning opportunities raise concerns that newly educated nurses lack proficiency in many psychomotor skills. Accordingly, there is an increased focus on learning in the SSC. However, it has been questioned if the pedagogical underpinning of teaching and learning in the SSC is missing or unclear. At a bachelor nursing education in Norway, there was a desire to change practice and enhance learning in the SSC by systematic use of The Model of Practical Skill Performance (Bjørk and Kirkevold, 2000). A participatory action research design was chosen. A pedagogical intervention was developed and implemented in 2010 in a cohort of eighty-seven first year bachelor nursing students during their basic nursing skill course. The intervention is shortly described. This article reports key issues and challenges that emerged during development of the new intervention. Data to inform the study were collected via thorough meeting minutes and the project leader's logbook, and analyzed using fieldnotes analysis. Six key issues and challenges were identified. These are presented and discussed consecutively in light of their importance for development and implementation of the new intervention. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Key issues in clinical and epidemiological research in complementary and alternative medicine--a systematic literature review.

    Science.gov (United States)

    Fischer, H Felix; Junne, Florian; Witt, Claudia; von Ammon, Klaus; Cardini, Francesco; Fønnebø, Vinjar; Johannessen, Helle; Lewith, George; Uehleke, Bernhard; Weidenhammer, Wolfgang; Brinkhaus, Benno

    2012-01-01

    In the last 2 decades there has been a large increase in publications on complementary and alternative medicine (CAM). However, CAM research methodology was heterogeneous and often of low quality. The aim of this systematic review was to investigate scientific publications with regards to general issues, concepts and strategies. We also looked at research priorities and methods employed to evaluate the clinical and epidemiological research of CAM in the past to identify the basis for consensus-based research strategies. We performed a systematic literature search for papers published between 1990 and 2010 in 7 electronic databases (Medline, Web of Science, PsychArticles, PsycInfo, CINAHL, EMBASE and Cochrane Library) on December 16 and 17, 2010. In addition, experts were asked to nominate relevant papers. Inclusion criteria were publications dealing with research methodology, priorities or complexities in the scientific evaluation of CAM. All references were assessed in a multistage process to identify relevant papers. From the 3,279 references derived from the search and 98 references contributed by CAM experts, 170 papers fulfilled the criteria and were included in the analysis. The following key issues were identified: difficulties in past CAM research (e.g., randomisation, blinding), utility of quantitative and qualitative research methods in CAM, priority setting in CAM research and specific issues regarding various CAM modalities. Most authors vote for the use of commonly accepted research methods to evaluate CAM. There was broad consensus that a mixed methods approach is the most suitable for gathering conclusive knowledge about CAM.

  20. Ten Top Tech Trends

    Science.gov (United States)

    McLester, Susan

    2008-01-01

    In this article, the author discusses the major technical issues, products, and practices of the day. The top ten tech trends are listed and discussed. These include: (1) data mining; (2) cyberbullying; (3) 21st century skills; (4) digital content; (5) learning at leisure; (6) personal responders; (7) mobile tools; (8) bandwidth; (9) open-source…

  1. Safe and inclusive research practices for qualitative research involving people with dementia: A review of key issues and strategies.

    Science.gov (United States)

    Novek, Sheila; Wilkinson, Heather

    2017-01-01

    Aim Developing strategies to ensure the safe participation of people with dementia in research is critical to support their wider inclusion in research and to advance knowledge in the areas of dementia policy and practice. Objectives This literature review synthesizes and critically appraises different approaches to promote the safe participation of people with dementia in qualitative research. Methods Two databases were searched for articles that discuss the methodological or ethical aspects of qualitative research involving people with dementia. We did not focus on informed consent or ethical review processes as these have been reviewed elsewhere. Findings Key issues that impact participant safety include: language, gatekeepers, the research relationship, communication, dealing with distress, knowledge dissemination, and researcher skills. Conclusion By synthesizing different approaches to safety and highlighting areas of debate, we hope to advance discussion and to contribute to the development of inclusive research methods.

  2. KEY ISSUES OF CONCEPTS' FORMATION OF THE NETWORK OF RESOURCE CENTER OF DISTANCE EDUCATION OF GENERAL EDUCATION INSTITUTIONS

    Directory of Open Access Journals (Sweden)

    Yuriy M. Bogachkov

    2013-06-01

    Full Text Available In the article the problem of constructing a network of resource centers for Distance Education to meet the needs of general secondary schools is presented. Modern educational trends in the use of Internet services in education are viewed.  Main contradictions, solution of which helps to create a network of resource centers, are identified. The definition of key terms related to the range of issues are given. The basic categories of participants, who  implementation of e-learning and networking are oriented on. There are considered the basic tasks of  distance education resource centers' functioning and types of supporting: personnel, regulatory, informative, systematic and  technical etc. The review of possible models of implementation of  students' distance education is reviewed . Three options for business models of resource centers, depending on funding  sources are offered.

  3. Rapid discharge from hospital in the last days of life: an evaluation of key issues and the discharge sister role.

    Science.gov (United States)

    Jones, Susan; Hamilton, Sharon; Nicholson, Alex

    2015-12-01

    When the time comes, most people wish to die at home. Nevertheless, many deaths occur in hospital, often because of delays in the discharge process. This study explored the issues surrounding rapid discharge from hospital in the final days of life, and evaluated the contribution of a discharge sister role. A qualitative design was used, incorporating focus groups and interviews with key stakeholders. A total of 75 staff and 7 carers participated. Participants highlighted the small window of opportunity available to facilitate a rapid but safe discharge from hospital. Early recognition of the last days of life was vital as was the availability of a skilled health professional, such as the discharge sister, to coordinate the patient's journey from hospital to preferred place of death. Rapid discharge is challenging and requires high levels of skill. The discharge sister navigated complex organisational systems to facilitate rapid discharge for those who might otherwise have died in hospital.

  4. Key issues for the development and application of the species sensitivity distribution (SSD) model for ecological risk assessment

    DEFF Research Database (Denmark)

    Xu, Fu-Liu; Li, Yi-Long; Wang, Yin

    2015-01-01

    The species sensitivity distribution (SSD) model is one of the most commonly used methods for ecological risk assessment based on the potentially affected fraction (PAF) of and the combined PAF (msPAF) as quantitative indicators. There are usually four steps for the development of SSD models...... and their applications: (1) obtain the toxicity data of the pollutants; (2) fit the SSD curves; (3) calculate the potentially affected fractions (PAFs) of the individual pollutants for the ecological risk assessment of an individual pollutant; and (4) calculate the accumulated multi-substance potentially affected...... fractions (msPAFs) for the joint ecological risk assessment of multiple pollutants. Among the above mentioned four steps, the first two steps are paramount. In the present study, the following six key issues are discussed: (1) how to select the appropriate species, (2) how to preprocess the toxicity data...

  5. Uncertainties in Biologically-Based Modeling of Formaldehyde-Induced Respiratory Cancer Risk: Identification of Key Issues

    Science.gov (United States)

    Subramaniam, Ravi P.; Chen, Chao; Crump, Kenny S.; DeVoney, Danielle; Fox, John F.; Portier, Christopher J.; Schlosser, Paul M.; Thompson, Chad M.; White, Paul

    2009-01-01

    In a series of articles and a health-risk assessment report, scientists at the CIIT Hamner Institutes developed a model (CIIT model) for estimating respiratory cancer risk due to inhaled formaldehyde within a conceptual framework incorporating extensive mechanistic information and advanced computational methods at the toxicokinetic and toxicodynamic levels. Several regulatory bodies have utilized predictions from this model; on the other hand, upon detailed evaluation the California EPA has decided against doing so. In this article, we study the CIIT model to identify key biological and statistical uncertainties that need careful evaluation if such two-stage clonal expansion models are to be used for extrapolation of cancer risk from animal bioassays to human exposure. Broadly, these issues pertain to the use and interpretation of experimental labeling index and tumor data, the evaluation and biological interpretation of estimated parameters, and uncertainties in model specification, in particular that of initiated cells. We also identify key uncertainties in the scale-up of the CIIT model to humans, focusing on assumptions underlying model parameters for cell replication rates and formaldehyde-induced mutation. We discuss uncertainties in identifying parameter values in the model used to estimate and extrapolate DNA protein cross-link levels. The authors of the CIIT modeling endeavor characterized their human risk estimates as “conservative in the face of modeling uncertainties.” The uncertainties discussed in this article indicate that such a claim is premature. PMID:18564991

  6. Experimental Study and Computational Simulations of Key Pebble Bed Thermo-mechanics Issues for Design and Safety

    Energy Technology Data Exchange (ETDEWEB)

    Tokuhiro, Akira; Potirniche, Gabriel; Cogliati, Joshua; Ougouag, Abderrafi

    2014-07-08

    An experimental and computational study, consisting of modeling and simulation (M&S), of key thermal-mechanical issues affecting the design and safety of pebble-bed (PB) reactors was conducted. The objective was to broaden understanding and experimentally validate thermal-mechanic phenomena of nuclear grade graphite, specifically, spheres in frictional contact as anticipated in the bed under reactor relevant pressures and temperatures. The contact generates graphite dust particulates that can subsequently be transported into the flowing gaseous coolent. Under postulated depressurization transients and with the potential for leaked fission products to be adsorbed onto graphite 'dust', there is the potential for fission products to escape from the primary volume. This is a design safety concern. Furthermore, earlier safety assessment identified the distinct possibility for the dispersed dust to combust in contact with air if sufficient conditions are met. Both of these phenomena were noted as important to design review and containing uncertainty to warrant study. The team designed and conducted two separate effects tests to study and benchmark the potential dust-generation rate, as well as study the conditions under which a dust explosion may occure in a standardized, instrumented explosion chamber.

  7. Taxonomic review of the chironomid genus Cricotopus v.d. Wulp (Diptera: Chironomidae) from Australia: keys to males, females, pupae and larvae, description of ten new species and comments on Paratrichocladius Santos Abreu.

    Science.gov (United States)

    Drayson, Nick; Cranston, Peter S; Krosch, Matt N

    2015-02-16

    The Australian species of the Orthocladiinae genus Cricotopus Wulp (Diptera: Chironomidae) are revised for larval, pupal, adult male and female life stages. Eleven species, ten of which are new, are recognised and keyed, namely Cricotopus acornis Drayson & Cranston sp. nov., Cricotopus albitarsis Hergstrom sp. nov., Cricotopus annuliventris (Skuse), Cricotopus brevicornis Drayson & Cranston sp. nov., Cricotopus conicornis Drayson & Cranston sp. nov., Cricotopus hillmani Drayson & Cranston, sp. nov., Cricotopus howensis Cranston sp. nov., Cricotopus parbicinctus Hergstrom sp. nov., Cricotopus tasmania Drayson & Cranston sp. nov., Cricotopus varicornis Drayson & Cranston sp. nov. and Cricotopus wangi Cranston & Krosch sp. nov. Using data from this study, we consider the wider utility of morphological and molecular diagnostic tools in untangling species diversity in the Chironomidae. Morphological support for distinguishing Cricotopus from Paratrichocladius Santo-Abreu in larval and pupal stages appears lacking for Australian taxa and brief notes are provided concerning this matter.

  8. Sustainable Sourcing of Global Agricultural Raw Materials: Assessing Gaps in Key Impact and Vulnerability Issues and Indicators.

    Science.gov (United States)

    Springer, Nathaniel P; Garbach, Kelly; Guillozet, Kathleen; Haden, Van R; Hedao, Prashant; Hollander, Allan D; Huber, Patrick R; Ingersoll, Christina; Langner, Megan; Lipari, Genevieve; Mohammadi, Yaser; Musker, Ruthie; Piatto, Marina; Riggle, Courtney; Schweisguth, Melissa; Sin, Emily; Snider, Sara; Vidic, Nataša; White, Aubrey; Brodt, Sonja; Quinn, James F; Tomich, Thomas P

    2015-01-01

    Understanding how to source agricultural raw materials sustainably is challenging in today's globalized food system given the variety of issues to be considered and the multitude of suggested indicators for representing these issues. Furthermore, stakeholders in the global food system both impact these issues and are themselves vulnerable to these issues, an important duality that is often implied but not explicitly described. The attention given to these issues and conceptual frameworks varies greatly--depending largely on the stakeholder perspective--as does the set of indicators developed to measure them. To better structure these complex relationships and assess any gaps, we collate a comprehensive list of sustainability issues and a database of sustainability indicators to represent them. To assure a breadth of inclusion, the issues are pulled from the following three perspectives: major global sustainability assessments, sustainability communications from global food companies, and conceptual frameworks of sustainable livelihoods from academic publications. These terms are integrated across perspectives using a common vocabulary, classified by their relevance to impacts and vulnerabilities, and categorized into groups by economic, environmental, physical, human, social, and political characteristics. These issues are then associated with over 2,000 sustainability indicators gathered from existing sources. A gap analysis is then performed to determine if particular issues and issue groups are over or underrepresented. This process results in 44 "integrated" issues--24 impact issues and 36 vulnerability issues--that are composed of 318 "component" issues. The gap analysis shows that although every integrated issue is mentioned at least 40% of the time across perspectives, no issue is mentioned more than 70% of the time. A few issues infrequently mentioned across perspectives also have relatively few indicators available to fully represent them. Issues in the

  9. Sustainable Sourcing of Global Agricultural Raw Materials: Assessing Gaps in Key Impact and Vulnerability Issues and Indicators.

    Directory of Open Access Journals (Sweden)

    Nathaniel P Springer

    Full Text Available Understanding how to source agricultural raw materials sustainably is challenging in today's globalized food system given the variety of issues to be considered and the multitude of suggested indicators for representing these issues. Furthermore, stakeholders in the global food system both impact these issues and are themselves vulnerable to these issues, an important duality that is often implied but not explicitly described. The attention given to these issues and conceptual frameworks varies greatly--depending largely on the stakeholder perspective--as does the set of indicators developed to measure them. To better structure these complex relationships and assess any gaps, we collate a comprehensive list of sustainability issues and a database of sustainability indicators to represent them. To assure a breadth of inclusion, the issues are pulled from the following three perspectives: major global sustainability assessments, sustainability communications from global food companies, and conceptual frameworks of sustainable livelihoods from academic publications. These terms are integrated across perspectives using a common vocabulary, classified by their relevance to impacts and vulnerabilities, and categorized into groups by economic, environmental, physical, human, social, and political characteristics. These issues are then associated with over 2,000 sustainability indicators gathered from existing sources. A gap analysis is then performed to determine if particular issues and issue groups are over or underrepresented. This process results in 44 "integrated" issues--24 impact issues and 36 vulnerability issues--that are composed of 318 "component" issues. The gap analysis shows that although every integrated issue is mentioned at least 40% of the time across perspectives, no issue is mentioned more than 70% of the time. A few issues infrequently mentioned across perspectives also have relatively few indicators available to fully represent

  10. Familienfreundlichkeit als Zukunftsfrage in Unternehmen [Family-friendliness in business as a key issue for the future

    Directory of Open Access Journals (Sweden)

    Stutzer, Erich

    2012-04-01

    Full Text Available [english] These days family-friendliness is a key issue for the future of businesses. Investments in a family conscious personnel policy are considered as forward-looking decisions in companies. This happens against the background of a sustainable personnel policy in times of a decrease in the number of employable persons, an increasing shortage of skilled workers and an ageing workforce. Family-friendly working conditions are becoming a key factor in the competition for staff. When choosing an employer, family-friendliness has become a crucial topic. Employment participation and skills of women, especially of mothers, have greatly increased. To facilitate the realisation of their wish to return to paid employment, however, measures to reconcile work and family are required.Family-conscious measures have been proven to lead to higher employee productivity. Job satisfaction and motivation of employees and accumulation of human capital increase, absenteeism declines, the return of investment rises. Fields of activity for family-friendly measures in companies range from working arrangements, parental leave and re-entry programmes and various child care offers to services for families. In connection with the demographic development the demand for a better reconciliation of work and elder care should in future become ever more important, just as the upkeep of the occupational skills and working capacity of an ageing workforce. Family-friendliness has to become an integral part of corporate culture. [german] Familienfreundlichkeit wird heute als wesentliche Zukunftsfrage für Unternehmen diskutiert und Investitionen in eine familienbewusste Personalpolitik gelten als zukunftsweisende Entscheidungen in Unternehmen. Dies geschieht vor dem Hintergrund einer zukunftsfähigen Personalpolitik in Zeiten zurückgehender Erwerbspersonenzahlen, eines zunehmenden Fachkräftemangels und der Alterung der Belegschaften. Familienfreundliche Arbeitsbedingungen werden

  11. Mexican Americans' Educational Barriers and Progress: Is the Magic Key within Reach? PERSPECTIVAS: Issues in Higher Education Policy and Practice. Issue No. 5, Spring 2016

    Science.gov (United States)

    Zambrana, Ruth Enid; Hurtado, Sylvia

    2016-01-01

    This policy brief is based on the edited book "The Magic Key: The Educational Journey of Mexican Americans from K-12 to College and Beyond" (Zambrana & Hurtado, 2015a), which focuses on the experiences of Mexican Americans in education. Drawing from an interdisciplinary corpus of work, the authors move beyond the rhetoric of progress…

  12. The Future We Want: Key Issues on Sustainable Development in Higher Education after Rio and the UN Decade of Education for Sustainable Development

    Science.gov (United States)

    Leal Filho, Walter; Manolas, Evangelos; Pace, Paul

    2015-01-01

    Purpose: This paper aims to provide a description of the achievements of the United Nations (UN) Decade of Education for Sustainable Development (2005-2014) with a focus on higher education, and it describes some of the key issues which will guide sustainable development in the coming years. Design/methodology/approach: The paper initially…

  13. Using Eight Key Questions as an Inquiry-Based Framework for Ethical Reasoning Issues in a General Education Earth Systems and Climate Change Course

    Science.gov (United States)

    Johnson, E. A.; Ball, T. C.

    2014-12-01

    An important objective in general education geoscience courses is to help students evaluate social and ethical issues based upon scientific knowledge. It can be difficult for instructors trained in the physical sciences to design effective ways of including ethical issues in large lecture courses where whole-class discussions are not practical. The Quality Enhancement Plan for James Madison University, "The Madison Collaborative: Ethical Reasoning in Action," (http://www.jmu.edu/mc/index.shtml) has identified eight key questions to be used as a framework for developing ethical reasoning exercises and evaluating student learning. These eight questions are represented by the acronym FOR CLEAR and are represented by the concepts of Fairness, Outcomes, Responsibilities, Character, Liberty, Empathy, Authority, and Rights. In this study, we use the eight key questions as an inquiry-based framework for addressing ethical issues in a 100-student general education Earth systems and climate change course. Ethical reasoning exercises are presented throughout the course and range from questions of personal behavior to issues regarding potential future generations and global natural resources. In the first few exercises, key questions are identified for the students and calibrated responses are provided as examples. By the end of the semester, students are expected to identify key questions themselves and justify their own ethical and scientific reasoning. Evaluation rubrics are customized to this scaffolding approach to the exercises. Student feedback and course data will be presented to encourage discussion of this and other approaches to explicitly incorporating ethical reasoning in general education geoscience courses.

  14. Argumentation as a Strategy for Increasing Preservice Teachers' Understanding of Climate Change, a Key Global Socioscientific Issue

    Science.gov (United States)

    Lambert, Julie L.; Bleicher, Robert E.

    2017-01-01

    Findings of this study suggest that scientific argumentation can play an effective role in addressing complex socioscientific issues (i.e. global climate change). This research examined changes in preservice teachers' knowledge and perceptions about climate change in an innovative undergraduate-level elementary science methods course. The…

  15. 75 FR 33615 - Draft EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments (EPA...

    Science.gov (United States)

    2010-06-14

    ... expert panel composed of scientists knowledgeable about technical issues related to dioxins and risk... audio-visual equipment (e.g., laptop computer and slide projector). In general, each presentation should... Christine Ross and the telephone number 703-347-8592 to the guard on duty. The guard will contact Ms. Ross...

  16. Increased Attention to Human Sexuality Can Improve HIV-AIDS Prevention Efforts: Key Research Issues and Directions.

    Science.gov (United States)

    Kelly, Jeffrey A.; Kalichman, Seth C.

    1995-01-01

    Discusses curtailing the human immunodeficiency virus (HIV) by helping people reduce high-risk sexual behavior. Reviews research in the relationship contexts of sexuality, including variations in monogamy, condom use in affectionate versus casual relationships, sexual communication, and coercion. Notes policy and training issues related to human…

  17. Animal welfare: a complex domestic and international public-policy issue--who are the key players?

    Science.gov (United States)

    Bayvel, A C David; Cross, Nicki

    2010-01-01

    Animal-welfare issues are usually portrayed in the media in a black-and-white fashion, with simple, single-perspective solutions proposed for what are often, in fact, complex policy issues. In this article, we argue that animal welfare is a multifaceted international and domestic public-policy issue that must take account of not only scientific, ethical, and economic issues but also religious, cultural, and international trade policy considerations. Management of animal welfare at a government policy level also requires an approach based on incremental change. Such change must be both science based and ethically principled, and the rate of change must recognize both the expectations of society and the constraints on the animal user. Ideally, such change should involve full ownership and buy-in from the affected animal user group. The range of stakeholders involved in the animal-welfare debate includes industry and producer groups, science bodies, and animal-welfare non-governmental organizations and professional groups, including the veterinary and legal professions. The veterinary profession, in particular, is expected to play an animal-welfare leadership role, and we discuss expectation versus reality at both a national and an international level. This latter discussion includes specific reference to the role of the World Organisation for Animal Health (the OIE) as an intergovernmental organization representing 175 countries and details some of the major achievements since the OIE assumed its international animal-welfare standard-setting role in 2002. We also address the role of the veterinary profession at national, regional, and international levels.

  18. Towards re-reforming the EU cohesion policy: Key issues in the debate and some thoughts on peripheral regions

    Directory of Open Access Journals (Sweden)

    Foutakis Dimitris

    2009-01-01

    Full Text Available Two years after the inception of the fourth programming period, the debate on post-2013 cohesion policy has already been launched. In fact, public consultation was launched in 2007 and considerable steps have followed since then, while others are about to start. At the same time, the new strategic guidelines and rules that guide cohesion policy have only been in place for a short period and as yet their impacts are not clear. Critical events and major political issues that concern the whole EU structure are the main factors behind this evolution. In particular, the economic recession in addition to the prospects for the new EU Treaty could be considered decisive elements in the launch of the debate on future cohesion policy. More specifically, among the issues highlighted in this context are the distinction between efficiency and equity objectives, the need for a place-based strategy, high growth sectors and their contribution to cohesion, and the potential for creativity and innovation. Overall, it seems like old dilemmas of spatial development recur, while contemporary ones also gain ground. The outcome of this debate is of significant importance for all EU regions not only in budgetary terms, but also in terms of strategic policy goals. This paper examines the above future policy issues with an emphasis on regions faced with particular difficulties such as less favored regions as well as those in the EU periphery.

  19. Customer orientation of cruise destinations in Newfoundland and Labrador, Canada – exploring key issues for ports and the cruise lines

    OpenAIRE

    Hull, John S.; Losekoot, Erwin

    2011-01-01

    This paper evaluates the customer needs of cruise passengers in a context of industry ports in the province of Newfoundland and Labrador, Canada. The study was conducted for the Cruise Association of Newfoundland and Labrador (CANAL) providing primary data as part of their assessment for their Port Readiness Program. The results are generated from a survey of 34 key decision-makers working in 24 ports in the province. Another survey representing the views of 12 cruise lines operating in these...

  20. Strengthening and redesigning flood risk governance in Europe: an overview of seven key issues and how they are being dealt with in six European countries

    Directory of Open Access Journals (Sweden)

    Hegger Dries

    2016-01-01

    Full Text Available European countries, especially urban areas, face increasing flood risks due to urbanization, increase of exposure and damage potential, and the effects of climate change. In literature and in practice, it is argued that a diversification of Flood Risk Management Strategies (FRMSs makes countries more flood resilient. The latter requires innovations in existing Flood Risk Governance Arrangements, development of new arrangements and the coordination of these arrangements, but it also requires these arrangements to be tailored to their physical and institutional context. Within the EU FP7 project STAR-FLOOD (2012-2016, a comparative analysis and evaluation of flood risk governance in Belgium, England, France, The Netherlands, Poland and Sweden has been conducted. The project identified at least seven key issues that are relevant for all researched countries (and probably also beyond. These key issues deal with the topics of (i diversifying Flood Risk Management Strategies (ii establishing connectivity between actors, levels and sectors through what we coin “bridging mechanisms” (iii achieving coproduction between public and private actors; (iv improving fragmented and often non-enforceable rule systems; (v optimising available resources for FRM; (vi operationalising the notion of “diversification of FRM strategies” in a country-specific way; (vii follow general design principles for improving FRM that are sufficiently tailored to local circumstances. Drawing on all project deliverables, this paper will briefly review each key issue, discuss salient similarities and differences between the countries and point at ways forward.

  1. A Policy Analysis and Quantitative Assessment of Key Issues Arising from Climate Change Negotiations Following COP 7

    Energy Technology Data Exchange (ETDEWEB)

    Sager, J. M

    2003-04-01

    This paper aims to assess the consequences of the amendments made to the Kyoto Protocol during COP 7 in Marrakech. Following a comprehensive policy analysis, the major issue of 'hot air' and CDM transaction costs is examined using the CERT model. This was done to show that primary supply regions, typically those with 'hot air' availability, might control the emissions reduction permit supply market and maximise net export revenues of permit supply by withholding 40 to 60% of available 'hot air' credits. The assumption that primary permit suppliers control permit price via a restriction of 'hot air' supply to the market will inadvertently leave a portion of the market share open to Non-Annex B CDM supply, despite potentially extreme variance in CDM transaction costs. A summary table of policy implications on the emissions reduction permit market is also included in the Appendix. (author)

  2. Heat, Human Performance, and Occupational Health: A Key Issue for the Assessment of Global Climate Change Impacts.

    Science.gov (United States)

    Kjellstrom, Tord; Briggs, David; Freyberg, Chris; Lemke, Bruno; Otto, Matthias; Hyatt, Olivia

    2016-01-01

    Ambient heat exposure is a well-known health hazard, which reduces human performance and work capacity at heat levels already common in tropical and subtropical areas. Various health problems have been reported. Increasing heat exposure during the hottest seasons of each year is a key feature of global climate change. Heat exhaustion and reduced human performance are often overlooked in climate change health impact analysis. Later this century, many among the four billion people who live in hot areas worldwide will experience significantly reduced work capacity owing to climate change. In some areas, 30-40% of annual daylight hours will become too hot for work to be carried out. The social and economic impacts will be considerable, with global gross domestic product (GDP) losses greater than 20% by 2100. The analysis to date is piecemeal. More analysis of climate change-related occupational health impact assessments is greatly needed.

  3. Key issues in the microchemical systems-based methanol fuel processor: Energy density, thermal integration, and heat loss mechanisms

    Science.gov (United States)

    Shah, Keyur; Besser, R. S.

    Microreactor technology is a promising approach in harnessing the high energy density of hydrocarbons and is being used to produce hydrogen-rich gases by reforming of methanol and other liquid hydrocarbons. However, on-demand H 2 generation for miniature proton exchange membrane fuel cell (PEMFC) systems has been a bottleneck problem, which has limited the development and demonstration of the PEMFC for high-performance portable power. A number of crucial challenges exist for the realization of practical portable fuel processors. Among these, the management of heat in a compact format is perhaps the most crucial challenge for portable fuel processors. In this study, a silicon microreactor-based catalytic methanol steam reforming reactor was designed, fabricated, and demonstrated in the context of complete thermal integration to understand this critical issue and develop a knowledge base required to rationally design and integrate the microchemical components of a fuel processor. Detailed thermal and reaction experiments were carried out to demonstrate the potential of microreactor-based on-demand H 2 generation. Based on thermal characterization experiments, the heat loss mechanisms and effective convective heat coefficients from the planar microreactor structure were determined and suggestions were made for scale up and implementation of packaging schemes to reduce different modes of heat losses.

  4. Key issues surrounding the health impacts of electronic nicotine delivery systems (ENDS) and other sources of nicotine.

    Science.gov (United States)

    Drope, Jeffrey; Cahn, Zachary; Kennedy, Rosemary; Liber, Alex C; Stoklosa, Michal; Henson, Rosemarie; Douglas, Clifford E; Drope, Jacqui

    2017-11-01

    Answer questions and earn CME/CNE Over the last decade, the use of electronic nicotine delivery systems (ENDS), including the electronic cigarette or e-cigarette, has grown rapidly. More youth now use ENDS than any tobacco product. This extensive research review shows that there are scientifically sound, sometimes competing arguments about ENDS that are not immediately and/or completely resolvable. However, the preponderance of the scientific evidence to date suggests that current-generation ENDS products are demonstrably less harmful than combustible tobacco products such as conventional cigarettes in several key ways, including by generating far lower levels of carcinogens and other toxic compounds than combustible products or those that contain tobacco. To place ENDS in context, the authors begin by reviewing the trends in use of major nicotine-containing products. Because nicotine is the common core-and highly addictive-constituent across all tobacco products, its toxicology is examined. With its long history as the only nicotine product widely accepted as being relatively safe, nicotine-replacement therapy (NRT) is also examined. A section is also included that examines snus, the most debated potential harm-reduction product before ENDS. Between discussions of NRT and snus, ENDS are extensively examined: what they are, knowledge about their level of "harm," their relationship to smoking cessation, the so-called gateway effect, and dual use/poly-use. CA Cancer J Clin 2017;67:449-471. © 2017 American Cancer Society. © 2017 American Cancer Society.

  5. Incentive-Based Conservation Programs in Developing Countries: A Review of Some Key Issues and Suggestions for Improvements

    Science.gov (United States)

    Spiteri, Arian; Nepalz, Sanjay K.

    2006-01-01

    Biodiversity conservation in developing countries has been a challenge because of the combination of rising human populations, rapid technological advances, severe social hardships, and extreme poverty. To address the social, economic, and ecological limitations of people-free parks and reserves, incentives have been incorporated into conservation programs in the hopes of making conservation meaningful to local people. However, such incentive-based programs have been implemented with little consideration for their ability to fulfill promises of greater protection of biodiversity. Evaluations of incentive-based conservation programs indicate that the approach continually falls short of the rhetoric. This article provides an overview of the problems associated with incentive-based conservation approaches in developing countries. It argues that existing incentive-based programs (IBPs) have yet to realize that benefits vary greatly at different “community” scales and that a holistic conceptualization of a community is essential to incorporate the complexities of a heterogeneous community when designing and implementing the IBPs. The spatial complexities involved in correctly identifying the beneficiaries in a community and the short-term focus of IBPs are two major challenges for sustaining conservation efforts. The article suggests improvements in three key areas: accurate identification of “target” beneficiaries, greater inclusion of marginal communities, and efforts to enhance community aptitudes.

  6. I metadati nelle biblioteche digitali: concetti chiave e prospettive Metadata issues in Digital Libraries: key concepts and perspectives

    Directory of Open Access Journals (Sweden)

    Iryna Solodovnik

    2011-12-01

    Full Text Available

    L'articolo si propone di esaminare il significato, il ruolo e le implicazioni di alcuni approcci utilizzati nella gestione della biblioteca digitale.

    L'innovazione nella gestione delle risorse online e il miglioramento della loro interoperabilità si può ottenere con una normalizzazione degli schemi di metadati attraverso l'uso di standard interoperabili e vocabolari internazionali e condivisi, e con l'arricchimento dato da ontologie e linked data, che sono alla base delle riflessioni sul web semantico e sulla costruzione di livelli semantici sulle descrizioni dei metadati.

    Attraverso l'esame di alcune metodologie innovative di rappresentazione dell'informazione (LODe-BD, SWAP, l'articolo mostra alcune modalità di creazione della conoscenza in ambiente digitale, con particolare riferimento ai dati bibliografici.

    The article sets out to investigate the meaning, role and implications of some information management approaches used in Digital Library practice. A greater focus on innovation in managing online resources and on improving their interoperability can be achieved by normalizing metadata schemas through interoperable standards, world-wide accepted controlled vocabularies as well as by their enrichment through qualitatively constructed ontologies and linked data, which are key to the expansion of the semantic reasoning on the web through building and connection of additional semantic layers on top of metadata descriptions. Reviewing some innovative methods of information representation (LODe-BD, SWAP, the paper tries to lead the reader to discover some new ways of knowledge creation in digital information environment, in particular what concerns digital bibliographic records.

  7. TUTOR TRAINING KEY ISSUE IN E-LEARNING / FORMACIÓN DE TUTORES. ASPECTO CLAVE EN ENSEÑANZA VIRTUAL

    Directory of Open Access Journals (Sweden)

    Andrea Astudillo

    2013-02-01

    Full Text Available The tutor has special relevance for the success of a virtual learning experience; the skills of a classroom teacher are not enough. Training processes for tutors are required to develop the necessary skills to perform the role that covers technical, pedagogical, social and administrative issues. This article presents an overview of the role of the tutors in virtual learning environments, the need to train these professionals and the experience of a Course on Tutoring, developed for the Center for Training, Experimentation and Educational Research. The Center has trained in a three-year period 1,611 tutors, to work in virtual courses offered to teachers by the Chilean Ministry of Education. The course is described, together with its instructional design, and its main results, like the high degree of retention and value assigned, all of which is understood as the first step in a process that is complemented by experience to become a virtual tutor.RESUMENEn el éxito de una experiencia formativa virtual, la figura del tutor cobra especial relevancia, las competencias de un docente presencial no son suficientes. Se requiere procesos formativos para que los tutores adquieran las competencias necesarias para desempeñar su rol que abarca las áreas técnica, pedagógica, social y administrativa. Este artículo presenta una visión general del rol del tutor en los entornos virtuales de aprendizaje, las necesidades de formar a estos profesionales y la experiencia del curso de tutores desarrollado para el Centro de Perfeccionamiento Experimentaciones e Investigaciones Pedagógicas que ha formado a los largo de tres años a 1.611 tutores, para actuar en los cursos virtuales que el Ministerio de Educación Chileno ofrece a sus docentes, se presenta el curso, su diseño instruccional, los principales resultados, como el alto grado de retención y valoración de esta instancia formativa, la cual se entiende como el primer paso de un proceso que se

  8. The role of the Department of Health and other key institutions in the promotion of equal opportunities, multi-cultural and anti-racist issues in nurse education.

    Science.gov (United States)

    Foolchand, M K

    2000-08-01

    Equal opportunities, multi-cultural and anti-racist issues have been discussed in nurse education for at least two decades. This paper discusses the extent to which the Department of Health (DoH), United Kingdom Central Council (UKCC) and the English National Board (ENB) have developed, implemented and evaluated the above policies in nurse education. A brief overview of the wider roles of the key institutions are outlined. More specifically, some of the major health and social policies implemented during the last two decades are reviewed. This review concludes that the major policies have neglected or marginalized equal opportunities and multi-cultural issues. This is especially so for anti-racism. It argues that the ideologies which underpin social and health policies reinforce white superiority and that these ideologies are rooted in Britain's history of colonialism.

  9. Assessing Campus Climates for Lesbian, Gay, Bisexual and Transgender (LGBT) Students: Methodological and Political Issues

    Science.gov (United States)

    Brown, Robert D.; Gortmaker, Valerie J.

    2009-01-01

    Methodological and political issues arise during the designing, conducting, and reporting of campus-climate studies for LGBT students. These issues interact; making a decision about a methodological issue (e.g., sample size) has an impact on a political issue (e.g., how well the findings will be received). Ten key questions that must be addressed…

  10. Key issues for mountain areas

    National Research Council Canada - National Science Library

    Price, Martin F; Jansky, Libor; Iatsenia, Andrei A

    2004-01-01

    ... and livelihood opportunities . . . ... Safdar Parvez and Stephen F. Rasmussen 86 6 Mountain tourism and the conservation of biological and cultural diversity... Wendy Brewer Lama and Nikhat Sattar 11...

  11. Key Issue: Enhancing Teacher Leadership

    Science.gov (United States)

    National Comprehensive Center for Teacher Quality, 2007

    2007-01-01

    "Teachers are leaders when they function in professional communities to affect student learning; contribute to school improvement; inspire excellence in practice; and empower stakeholders to participate in educational improvement" (Childs-Bowen, Moller, & Scrivner, 2000, p. 28). Enhancing teacher leadership can help schools and districts reach the…

  12. CRITICAL ISSUES AND KEY POINTS FROM THE SURVEY TO THE CREATION OF THE HISTORICAL BUILDING INFORMATION MODEL: THE CASE OF SANTO STEFANO BASILICA

    Directory of Open Access Journals (Sweden)

    C. Castagnetti

    2017-05-01

    Full Text Available The new era of designing in architecture and civil engineering applications lies in the Building Information Modeling (BIM approach, based on a 3D geometric model including a 3D database. This is easier for new constructions whereas, when dealing with existing buildings, the creation of the BIM is based on the accurate knowledge of the as-built construction. Such a condition is allowed by a 3D survey, often carried out with laser scanning technology or modern photogrammetry, which are able to guarantee an adequate points cloud in terms of resolution and completeness by balancing both time consuming and costs with respect to the request of final accuracy. The BIM approach for existing buildings and even more for historical buildings is not yet a well known and deeply discussed process. There are still several choices to be addressed in the process from the survey to the model and critical issues to be discussed in the modeling step, particularly when dealing with unconventional elements such as deformed geometries or historical elements. The paper describes a comprehensive workflow that goes through the survey and the modeling, allowing to focus on critical issues and key points to obtain a reliable BIM of an existing monument. The case study employed to illustrate the workflow is the Basilica of St. Stefano in Bologna (Italy, a large monumental complex with great religious, historical and architectural assets.

  13. Critical Issues and Key Points from the Survey to the Creation of the Historical Building Information Model: the Case of Santo Stefano Basilica

    Science.gov (United States)

    Castagnetti, C.; Dubbini, M.; Ricci, P. C.; Rivola, R.; Giannini, M.; Capra, A.

    2017-05-01

    The new era of designing in architecture and civil engineering applications lies in the Building Information Modeling (BIM) approach, based on a 3D geometric model including a 3D database. This is easier for new constructions whereas, when dealing with existing buildings, the creation of the BIM is based on the accurate knowledge of the as-built construction. Such a condition is allowed by a 3D survey, often carried out with laser scanning technology or modern photogrammetry, which are able to guarantee an adequate points cloud in terms of resolution and completeness by balancing both time consuming and costs with respect to the request of final accuracy. The BIM approach for existing buildings and even more for historical buildings is not yet a well known and deeply discussed process. There are still several choices to be addressed in the process from the survey to the model and critical issues to be discussed in the modeling step, particularly when dealing with unconventional elements such as deformed geometries or historical elements. The paper describes a comprehensive workflow that goes through the survey and the modeling, allowing to focus on critical issues and key points to obtain a reliable BIM of an existing monument. The case study employed to illustrate the workflow is the Basilica of St. Stefano in Bologna (Italy), a large monumental complex with great religious, historical and architectural assets.

  14. A Cross-Continental Study on Children's Drawings of Football Players: Implications for Understanding Key Issues and Controversies in Human Figure Drawings

    Directory of Open Access Journals (Sweden)

    Bahman Baluch

    2017-08-01

    Full Text Available Professionals examine various aspects of girls’ and boys’ drawings as a way of understanding their intelligence, personality and emotional state. However, the extent to which such measures could be universally generalised or attributed to a specific cultural norm is still a debatable issue. In the present study five key features of children’s drawings namely: the size (height of the drawings, profile or full face, figure in action or static, shaded or non-shaded and the nature of additional details were examined from a cross-cultural perspective, and by providing a topic (football for which children’s drawing of a human figure could provide opportunities for the latter indices to manifest and flourish. Children from three countries; England, Iran and Brazil, representing three continents took part in this study. The participants were asked to draw a football player from their own country and from the other participating countries. The results showed that Brazilian children differ from Iranian and English children by drawing significantly smaller figures and putting more football action in the drawings. Shading of the figure drawn was more prevalent amongst English children. Such findings have implications for the interpretation of key aspects of children's drawings in educational, clinical and therapeutic settings and from a universal vs. culturally-specific viewpoint.

  15. A Cross-Continental Study on Children's Drawings of Football Players: Implications for Understanding Key Issues and Controversies in Human Figure Drawings.

    Science.gov (United States)

    Baluch, Bahman; Duffy, Linda J; Badami, Rokhsareh; Pereira, Elisangela C Ap

    2017-08-01

    Professionals examine various aspects of girls' and boys' drawings as a way of understanding their intelligence, personality and emotional state. However, the extent to which such measures could be universally generalised or attributed to a specific cultural norm is still a debatable issue. In the present study five key features of children's drawings namely: the size (height) of the drawings, profile or full face, figure in action or static, shaded or non-shaded and the nature of additional details were examined from a cross-cultural perspective, and by providing a topic (football) for which children's drawing of a human figure could provide opportunities for the latter indices to manifest and flourish. Children from three countries; England, Iran and Brazil, representing three continents took part in this study. The participants were asked to draw a football player from their own country and from the other participating countries. The results showed that Brazilian children differ from Iranian and English children by drawing significantly smaller figures and putting more football action in the drawings. Shading of the figure drawn was more prevalent amongst English children. Such findings have implications for the interpretation of key aspects of children's drawings in educational, clinical and therapeutic settings and from a universal vs. culturally-specific viewpoint.

  16. End-of-life care in advanced kidney disease: ethical and legal issues and key challenges for black and minority ethnic groups.

    Science.gov (United States)

    Cronin, Antonia J

    2014-09-01

    Advances in modern medical technology have gone so far that it is now possible for machinery to keep people alive. To some extent this has led to a misperception in society that death can almost always be postponed because life-sustaining extracorporeal machinery of some sort or another, for example a dialysis machine, can prevent it. However, for some, being kept alive connected to a dialysis machine for four hours three times a week does not represent or even come close to an existence or quality of life they consider valuable. It may even cause unnecessary distress. This may be because they have reached a point at the end of their lives where they would like the focus of their treatment or care to become that which enables them to live as well as possible until they die. In these circumstances treatment and care should properly be that which enables the supportive and palliative care needs of both patient and family to be identified and met throughout the last phase of life and into bereavement. Identifying and acknowledging the importance of such a paradigm shift in the delivery of healthcare, and above all facilitating it, includes taking on the responsibility, incumbent upon us all, to address the ethical issues that are brought into focus. In this paper, I examine some of these issues. I consider the ways in which underlying theoretical ethical principles have informed the development of professional guidance and highlight the dynamic relationship this guidance has with the law. Finally, I demonstrate the ways in which it can be usefully applied to inform and assist clinical decision-making. Key challenges for BAME groups are addressed. © 2014 European Dialysis and Transplant Nurses Association/European Renal Care Association.

  17. Synthesizing Nanomaterials for Energy Applications: Probing Activity as a Function of Composition, Morphology and Purity to Address Key Issues Associated with Fuel Cells and Li-Ion Batteries

    Science.gov (United States)

    Scofield, Megan Elaine

    With the growing need to find alternative clean energy sources to fossil fuels, research into developing efficient fuel cells and batteries stands at the forefront of this grand effort. However, before mass commercialization, fundamental key issues need to be addressed. For example, fuel cells are subject to high catalyst costs and poor durability of the underlying carbon support. As a way to alleviate these issues, we have synthesized ultrathin one-dimensional (1D) alloy nanowires to probe the effect of composition, purity, and one-dimensionality upon the observed overall activity, performance, and durability. In terms of chemical composition, crystalline ultrathin PtM alloy nanowires (NWs) ('M' = Fe, Co, Ru, Cu, and Au) were generated and subsequently evaluated for the hydrogen oxidation reaction (HOR). Additionally, ternary-based catalysts were synthesized (PtRuFe) in order to analyze how chemical composition influences CO tolerance as well as methanol oxidation reaction (MOR) and formic acid oxidation reaction (FAOR) activities. In both cases, we utilized a sustainably mild, ambient wet-synthesis method for the fabrication of chemically pure and crystalline systems in order to fabricate ultrathin, homogeneous alloy NWs. Moreover, in these studies, our NW systems exhibit favorable synergistic electronic effects with respect to controls. To address another fundamental issue associated with the durability of fuel cells, we have synthesized various metal oxide and perovskite materials of different sizes and chemical compositions as supports for Pt nanoparticles (NPs). Specifically, we have demonstrated favorable metal support interactions between the Pt NPs and the SrRuO3 NP supports, which lead to increased MOR activity as compared with not only the other metal oxide supports tested but also the commercial Pt NP/C standard. In terms of Li-ion batteries, LiFePO4 materials have become increasingly popular as a cathode material due to the many benefits they possess

  18. Eco-innovation, international trade, WTO and climate: Key issues for an ecological industrial policy. Documentation of a workshop on March 12, 2008

    Energy Technology Data Exchange (ETDEWEB)

    Hoppe, Jutta; Kahlenborn, Walter [Adelphi Research, Berlin (Germany); Gather, Corinna (eds.) [Umweltbundesamt, Dessau (Germany)

    2009-01-15

    Within the meeting of the German Federal Environment Agency (Dessau, Federal Republic of Germany) and the German Federal Ministry for the Environment, Nature Conservation and Natural Safety (Berlin, Federal Republic of Germany) at 12th March, 2008, the following reports were held: (a) Trade Policy and Climate Change - An overview from the perspective of an ecological industrial policy (Jutta Hoppe et al.); (b) Kyoto, Post-Kyoto and the WTO (Malena Sell); (c) Climate change, trade and competitiveness (Aaron Cosby, John Drexhage); (d) Unilateral climate policy and implications for trade policy (Susanne Droege); (e) Trade in environmental goods and services relevant to climate-change mitigation: Opportunities and challenges for new industries in the European Union (Mahesh Sugathan); (f) The relevance of WTO activities and rules in the climate change debate (Ludivine Tamiotti); (g) Like-products, energy standards and labelling (Roland Ismer); (h) EC Trade policy and climate challenges: An overview of EC trade policy approaches to climate change (Ditte Juul-Joergensen); (i) Opportunities and constraints for an integrated European climate and trade policy (Ulrich Hoffmann); (j) Climate change, eco-innovation, and EU trade policy: a critical assessment (Daniel Mittler); (k) Resume: Key Issues for an Ecological Industrial policy (Jutta Hoppe, Walter Kahlenborn).

  19. Lining up higher education. Trends in selected higher education statistics in ten Western countries (IHEM Trendreport 2004)

    NARCIS (Netherlands)

    Kaiser, Franciscus; Hillegers, Harm; Legro, Iwen

    2005-01-01

    In this fourth IHEM trend report, key statistical issues like student flows (new entrants, enrolment, and graduation, broken down by discipline and gender), rates of participation, staff, and finance are presented for the ten IHEM core countries over the period 1995 till recent. National statistical

  20. Nurses' Perceptions and Practices Toward Clinical Alarms in a Transplant Cardiac Intensive Care Unit: Exploring Key Issues Leading to Alarm Fatigue.

    Science.gov (United States)

    Sowan, Azizeh Khaled; Tarriela, Albert Fajardo; Gomez, Tiffany Michelle; Reed, Charles Calhoun; Rapp, Kami Marie

    2015-03-16

    Intensive care units (ICUs) are complex work environments where false alarms occur more frequently than on non-critical care units. The Joint Commission National Patient Safety Goal .06.01.01 targeted improving the safety of clinical alarm systems and required health care facilities to establish alarm systems safety as a hospital priority by July 2014. An important initial step toward this requirement is identifying ICU nurses' perceptions and common clinical practices toward clinical alarms, where little information is available. Our aim was to determine perceptions and practices of transplant/cardiac ICU (TCICU) nurses toward clinical alarms and benchmark the results against the 2011 Healthcare Technology Foundation's (HTF) Clinical Alarms Committee Survey. A quality improvement project was conducted on a 20-bed TCICU with 39 full- and part-time nurses. Nurses were surveyed about their perceptions and attitudes toward and practices on clinical alarms using an adapted HTF clinical alarms survey. Results were compared to the 2011 HTF data. Correlations among variables were examined. All TCICU nurses provided usable responses (N=39, 100%). Almost all nurses (95%-98%) believed that false alarms are frequent, disrupt care, and reduce trust in alarm systems, causing nurses to inappropriately disable them. Unlike the 2011 HTF clinical alarms survey results, a significantly higher percentage of our TCICU nurses believed that existing devices are complex, questioned the ability and adequacy of the new monitoring systems to solve alarm management issues, pointed to the lack of prompt response to alarms, and indicated the lack of clinical policy on alarm management (Ppractices related to clinical alarms are key elements for designing contextually sensitive quality initiatives to fight alarm fatigue. Alarm management in ICUs is a multidimensional complex process involving usability of monitoring devices, and unit, clinicians, training, and policy-related factors. This

  1. Affordances: Ten Years On

    Science.gov (United States)

    Brown, Jill P.; Stillman, Gloria

    2014-01-01

    Ten years ago the construct, affordance, was rising in prominence in scholarly literature. A proliferation of different uses and meanings was evident. Beginning with its origin in the work of Gibson, we traced its development and use in various scholarly fields. This paper revisits our original question with respect to its utility in mathematics…

  2. Tens bij bevallingen

    NARCIS (Netherlands)

    Tuin-Nuis, F.D.F.

    2000-01-01

    TENS (Transcutane Electrische Neuro Stimulatie) is een pijnverlichtingsmethode die berust op de Gate Control Theory van Melzack en Wall. Door middel van electrische pulsen via de huid zou de geleiding van nociceptieve signalen (pijnprikkels) worden beïnvloed en zou het lichaam endorfinen aanmaken:

  3. Powers of ten

    CERN Multimedia

    Pyramid FILMS

    1977-01-01

    Powers of Ten is a 1977 short documentary film written and directed by Charles Eames and his wife, Ray. The film depicts the relative scale of the Universe in factors of ten (see also logarithmic scale and order of magnitude). The film begins with an aerial image of a man reclining on a blanket; the view is that of one meter across. The viewpoint, accompanied by expository voiceover, then slowly zooms out to a view ten meters across ( or 101 m in standard form), revealing that the man is picnicking in a park with a female companion. The zoom-out continues, to a view of 100 meters (102 m), then 1 kilometer (103 m), and so on, increasing the perspective—the picnic is revealed to be taking place near Soldier Field on Chicago's waterfront—and continuing to zoom out to a field of view of 1024 meters, or the size of the observable universe. The camera then zooms back in to the picnic, and then to views of negative powers of ten—10-1 m (10 centimeters), and so forth, until we are viewing a carbon nucl...

  4. Ten Utah Painters

    OpenAIRE

    Whitlock, Andrew

    1984-01-01

    Today the art world is rich and diverse with regional as well as national art centers. As in the past, art is alive and well in Utah. The show Ten Utah Painters invites us to see and experiece what some of Utah's best contemporary artists are doing. Their paintings invite us to look and to enjoy but also to learn and open up our visual senses to a broader vista.

  5. Epidemiological analysis of tuberculosis in Ethiopia: A ten-year ...

    African Journals Online (AJOL)

    A time-series study design was applied to analyze the ten-year trends of Tuberculosis in Ethiopia. Data on ten-key indicators for the period of 2000-2009 was obtained from the Ministry of Health public documents. Five stratifying variables were used to analyze the trends in the key TB indicators. The data on the indicators ...

  6. Magna Carta at 800: Ten Key Questions Answered

    Science.gov (United States)

    Kaplan, Howard

    2014-01-01

    2015 marks the 800th anniversary of Magna Carta. For Americans, this iconic document is a formative element of our own legal and political heritage. This "Lessons on the Law" column offers an overview of the "Great Charter," why it is significant, and what students and teachers should know about it. The article also highlights…

  7. Mine water pollution - acid mine decant, effluent and treatment: a consideration of key emerging issues that may impact the state of the environment

    CSIR Research Space (South Africa)

    Oelofse, Suzanna HH

    2008-07-01

    Full Text Available A major environmental problem relating to mining in many parts of the world is uncontrolled discharge of contaminated water (or decant) from abandoned mines. This document provides information on emerging issues that may affect the future state...

  8. Analysis of Variance of the Effects of a Project’s Location on Key Issues and Challenges in Post-Disaster Reconstruction Projects

    Directory of Open Access Journals (Sweden)

    Dzulkarnaen Ismail

    2017-11-01

    Full Text Available After a disaster, the reconstruction phase is driven by immediate challenges. One of the main challenges in the post-disaster period is the way that reconstruction projects are implemented. Reconstruction cannot move forward until some complex issues are settled. The purposes of this research are to highlight the issues and challenges in post-disaster reconstruction (PDR projects and to determine the significant differences between the issues and challenges in different locations where PDR projects are carried out. The researchers collected data within international non-governmental organisations (INGOs on their experience of working with PDR projects. The findings of this research provide the foundation on which to build strategies for avoiding project failures; this may be useful for PDR project practitioners in the future.

  9. Chiropractic Health Care: A National Study of Cost of Education, Service Utilization, Number of Practicing Doctors of Chiropractic, and Other Key Policy Issues. Volumes I-II.

    Science.gov (United States)

    von Kuster, Thomas, Jr.

    Results from the first federally sponsored study of the chiropractic health care profession are presented, and a broad range of facts and issues of concern to policy-makers, the profession, and the public are described. The two-year project included three national surveys of: service providers (doctors of chiropractic in practice more than two…

  10. The ten thousand Kims

    Science.gov (United States)

    Baek, Seung Ki; Minnhagen, Petter; Kim, Beom Jun

    2011-07-01

    In Korean culture, the names of family members are recorded in special family books. This makes it possible to follow the distribution of Korean family names far back in history. It is shown here that these name distributions are well described by a simple null model, the random group formation (RGF) model. This model makes it possible to predict how the name distributions change and these predictions are shown to be borne out. In particular, the RGF model predicts that for married women entering a collection of family books in a certain year, the occurrence of the most common family name 'Kim' should be directly proportional to the total number of married women with the same proportionality constant for all the years. This prediction is also borne out to a high degree. We speculate that it reflects some inherent social stability in the Korean culture. In addition, we obtain an estimate of the total population of the Korean culture down to the year 500 AD, based on the RGF model, and find about ten thousand Kims.

  11. Ten Things Every Professor Should Know about Assessment

    Science.gov (United States)

    Wolf, Kenneth; Dunlap, Joanna; Stevens, Ellen

    2012-01-01

    This article describes ten key assessment practices for advancing student learning that all professors should be familiar with and strategically incorporate in their classrooms and programs. Each practice or concept is explained with examples and guidance for putting it into practice. The ten are: learning outcomes, performance assessments,…

  12. [Key issues in researching spirituality and religiosity in the light of the ASPIRES instrument (Assessment of Spirituality and Religious Sentiments) Developed by Ralph Piedmont].

    Science.gov (United States)

    Tomcsányi, Teodóra; Ittzés, András; Horváth-Szabó, Katalin; Martos, Tamás; Szabó, Tünde

    2010-01-01

    Our article reviews the major questions raised by the psychological research of spirituality and religion, as well as the historical background of this research area. In our view the scientific exploration of spirituality and religion constitutes a process that allows for both empirical and hermeneutical approaches and as such it is open for a dialogue with other branches of social sciences. The most important topics addressed by the article include: 1. possible conceptualizations of the terms spirituality and religion; the connection between the two; similarities and differences; 2. the interpretation of spirituality as a dimension of the personality; 3. the question of measurement of spirituality and tools of its measurement; 4. the effects of spirituality; and 5. the culture relatedness of research data. Finally we demonstrate how the ASPIRES scale recently developed by R. Piedmont, its theoretical approach, development process, and empirical results try to answer these key questions.

  13. Review of Current State of the Art and Key Design Issues With Potential Solutions for Liquid Hydrogen Cryogenic Storage Tank Structures for Aircraft Applications

    Science.gov (United States)

    Mital, Subodh K.; Gyekenyesi, John Z.; Arnold, Steven M.; Sullivan, Roy M.; Manderscheid, Jane M.; Murthy, Pappu L. N.

    2006-01-01

    Due to its high specific energy content, liquid hydrogen (LH2) is emerging as an alternative fuel for future aircraft. As a result, there is a need for hydrogen tank storage systems, for these aircraft applications, that are expected to provide sufficient capacity for flight durations ranging from a few minutes to several days. It is understood that the development of a large, lightweight, reusable cryogenic liquid storage tank is crucial to meet the goals of and supply power to hydrogen-fueled aircraft, especially for long flight durations. This report provides an annotated review (including the results of an extensive literature review) of the current state of the art of cryogenic tank materials, structural designs, and insulation systems along with the identification of key challenges with the intent of developing a lightweight and long-term storage system for LH2. The broad classes of insulation systems reviewed include foams (including advanced aerogels) and multilayer insulation (MLI) systems with vacuum. The MLI systems show promise for long-term applications. Structural configurations evaluated include single- and double-wall constructions, including sandwich construction. Potential wall material candidates are monolithic metals as well as polymer matrix composites and discontinuously reinforced metal matrix composites. For short-duration flight applications, simple tank designs may suffice. Alternatively, for longer duration flight applications, a double-wall construction with a vacuum-based insulation system appears to be the most optimum design. The current trends in liner material development are reviewed in the case that a liner is required to minimize or eliminate the loss of hydrogen fuel through permeation.

  14. Public health economics: a systematic review of guidance for the economic evaluation of public health interventions and discussion of key methodological issues

    Science.gov (United States)

    2013-01-01

    Background If Public Health is the science and art of how society collectively aims to improve health, and reduce inequalities in health, then Public Health Economics is the science and art of supporting decision making as to how society can use its available resources to best meet these objectives and minimise opportunity cost. A systematic review of published guidance for the economic evaluation of public health interventions within this broad public policy paradigm was conducted. Methods Electronic databases and organisation websites were searched using a 22 year time horizon (1990–2012). References of papers were hand searched for additional papers for inclusion. Government reports or peer-reviewed published papers were included if they; referred to the methods of economic evaluation of public health interventions, identified key challenges of conducting economic evaluations of public health interventions or made recommendations for conducting economic evaluations of public health interventions. Guidance was divided into three categories UK guidance, international guidance and observations or guidance provided by individual commentators in the field of public health economics. An assessment of the theoretical frameworks underpinning the guidance was made and served as a rationale for categorising the papers. Results We identified 5 international guidance documents, 7 UK guidance documents and 4 documents by individual commentators. The papers reviewed identify the main methodological challenges that face analysts when conducting such evaluations. There is a consensus within the guidance that wider social and environmental costs and benefits should be looked at due to the complex nature of public health. This was reflected in the theoretical underpinning as the majority of guidance was categorised as extra-welfarist. Conclusions In this novel review we argue that health economics may have come full circle from its roots in broad public policy economics. We may

  15. Public health economics: a systematic review of guidance for the economic evaluation of public health interventions and discussion of key methodological issues.

    Science.gov (United States)

    Edwards, Rhiannon Tudor; Charles, Joanna Mary; Lloyd-Williams, Huw

    2013-10-24

    If Public Health is the science and art of how society collectively aims to improve health, and reduce inequalities in health, then Public Health Economics is the science and art of supporting decision making as to how society can use its available resources to best meet these objectives and minimise opportunity cost. A systematic review of published guidance for the economic evaluation of public health interventions within this broad public policy paradigm was conducted. Electronic databases and organisation websites were searched using a 22 year time horizon (1990-2012). References of papers were hand searched for additional papers for inclusion. Government reports or peer-reviewed published papers were included if they; referred to the methods of economic evaluation of public health interventions, identified key challenges of conducting economic evaluations of public health interventions or made recommendations for conducting economic evaluations of public health interventions. Guidance was divided into three categories UK guidance, international guidance and observations or guidance provided by individual commentators in the field of public health economics. An assessment of the theoretical frameworks underpinning the guidance was made and served as a rationale for categorising the papers. We identified 5 international guidance documents, 7 UK guidance documents and 4 documents by individual commentators. The papers reviewed identify the main methodological challenges that face analysts when conducting such evaluations. There is a consensus within the guidance that wider social and environmental costs and benefits should be looked at due to the complex nature of public health. This was reflected in the theoretical underpinning as the majority of guidance was categorised as extra-welfarist. In this novel review we argue that health economics may have come full circle from its roots in broad public policy economics. We may find it useful to think in this broader

  16. BIOPROTA Key Issues in Biosphere Aspects of Assessment of the Long-term Impact of Contaminant Releases Associated with Radioactive Waste Management Theme 2: Task 7:Modelling Processes in the Geosphere Biosphere Interface Zone

    Energy Technology Data Exchange (ETDEWEB)

    Pinedo, P.; Smith, G.; Aguero, A.; Albrecht, A.; Bath, A.; Benhabderrahmane, H.; Van Dorp, F.; Kautsky, U.; Klos, R.; Laciok, A.; Milodowski, T.; Selroos, J.O.; Simon, I.; Texier, D.; Thorne, M.; Willans, M.

    2005-07-01

    This document reports on BIOPROTA Theme 2, task 7 which investigated modelling processes in the geosphere- biosphere interface zone (GBIZ) during performance assessments. Modelling issues in the treatment of the GBIZ are identified. A large proportion of the identified issues concern modelling radionuclide behaviour in near surface aquifers which are subject to relatively high gradients in chemical and other conditions. Other key issues concern transfer of radionuclides through the unsaturated zone above aquifers, bearing in mind the scope for erosion and variations in the level of the phreatic surface and also the consideration of environmental change. A number of research areas are highlighted that are aimed at addressing each of the identified issues in the treatment of GBIZ. These include (i) Developing of a current statement of continuing problems, and hence clarify and justify the need to do more; (ii) Conducting a review of site investigations as they have been done already, and determine whether they meet performance assessment requirements; (iii) Identifying scenarios and FEPs considered in current treatments; and, (iv) Conducting source-pathway-receptor analysis to demonstrate comprehensiveness of the overall scenario identification process. The objectives of these activities would be to determine the potential to reduce uncertainties and/or conservative assumptions in assessment of radionuclide transfer from the geosphere to biosphere domains, taking account of environmental change; and to develop guidance on site-characterisation needs at different types of site, as regards the near-surface features. (Author) 23 refs.

  17. Transcutaneous electric nerve stimulation (TENS) in dentistry- A review.

    Science.gov (United States)

    Kasat, Vikrant; Gupta, Aditi; Ladda, Ruchi; Kathariya, Mitesh; Saluja, Harish; Farooqui, Anjum-Ara

    2014-12-01

    Transcutaneous electric nerve stimulation (TENS) is a non-pharmacological method which is widely used by medical and paramedical professionals for the management of acute and chronic pain in a variety of conditions. Similarly, it can be utilized for the management of pain during various dental procedures as well as pain due to various conditions affecting maxillofacial region. This review aims to provide an insight into clinical research evidence available for the analgesic and non analgesic uses of TENS in pediatric as well as adult patients related to the field of dentistry. Also, an attempt is made to briefly discuss history of therapeutic electricity, mechanism of action of TENS, components of TENs equipment, types, techniques of administration, advantages and contradictions of TENS. With this we hope to raise awareness among dental fraternity regarding its dental applications thereby increasing its use in dentistry. Key words:Dentistry, pain, TENS.

  18. Ten Years in the Academic Integrity Trenches: Experiences and Issues

    Science.gov (United States)

    Atkinson, Doug; Nau, S. Zaung; Symons, Christine

    2016-01-01

    In 2016, our university launched its Academic Integrity Program (AIP) in order to promote and protect academic integrity. All commencing students must complete this online AIP within 14 days of starting their course. Satisfactory completion of this module with a test score of 80% is required before students can access their course materials.…

  19. COMPETITIVENESS - KEY ISSUES OF THE ROMANIAN ECONOMY

    Directory of Open Access Journals (Sweden)

    Gabriela-Liliana, CIOBAN

    2014-11-01

    Full Text Available Based on the theory that competitiveness plays an increasingly powerful role in creating prosperity, wealth, a large number of economists, researchers, scientists, highlight a number of approaches aimed, on the one hand, on the analysis of competitiveness at national or regional level, and on the other hand, on the ability of local firms to achieve competitive products and to commercialize them in the extern markets. In this context we aim to analyze and develop strategies and methods to help identify competitive areas at a national level. This is necessary because in our opinion the competitiveness of a company and / or country is more than wealth itself; it means a systematic process of wealth creation, plus a social system in which most citizens have access to material wealth. We consider in this respect that a country cannot automatically be considered competitive only if it is rich in natural resources. In our view, a competitive country creates wealth through labor, talent and organization and thus it manages to have a productive and creative potential making it independent of material resources.

  20. Environmental conflicts: Key issues and management implications

    African Journals Online (AJOL)

    environmental conflicts, climate change and environmental conflicts, and management implications. The section ... water, land and natural resource management conflicts. This is followed by a discussion of .... are at risk because they are exposed more frequently to such shocks and they do not usually have the necessary ...

  1. Pakistan: Key Current Issues and Developments

    Science.gov (United States)

    2010-06-01

    are said to have shifted from a critical approach to a gentler, “more-flies-with- honey ” method of building trust with Pakistani military leaders who...significant damper on commerce and everyday activities, causing factory shutdowns and rioting by mobs angry with price hikes and shortages. A 2009 survey

  2. Key micromechanics issues in integrated material design

    Science.gov (United States)

    Bennoura, M.; Aboutajeddine, A.

    2017-03-01

    Nowadays the acceleration of material discovery is essential more than ever to hold the fast evolving requirements of innovative products. This acceleration depends on our ability to set up a material design process for tailoring materials from targeted engineering performances. One of the important building block passages, in the material design journey, is the bridging of micro-scale to meso-scale through micromechanical models. Unfortunately, these models include a lot of uncertainties resulting from their inbuilt ad-hoc assumptions, which inevitably impacts the material design process performance. In the present paper, robust design methods are reviewed and subsequently applied to quantify uncertainty in micromechanical models and mitigate its impact on material design performances. This includes examining principles for evaluating the level degree of uncertainty on material design process, and their use in micromechanical models. Also, developing robust design approaches to alleviate uncertainty effects and improve the quality of the design performance. Ultimately, the limitations of these approaches are discussed and the research opportunities, to overcome the shortness of actual approaches in respect to micromechanical models, are clarified.

  3. Cancer Patient Experience in the Teenage Young Adult Population- Key Issues and Trends Over Time: An Analysis of the United Kingdom National Cancer Patient Experience Surveys 2010-2014.

    Science.gov (United States)

    Furness, Caroline L; Smith, Lesley; Morris, Eva; Brocklehurst, Caroline; Daly, Sasha; Hough, Rachael E

    2017-09-01

    Improving outcomes for teenagers and young adults (TYA) with cancer is a key element of the national cancer strategy in England. Recognition of the unique needs of this group has led to the development of recommendations for specific models of care and delivery of this care through the provision of dedicated clinical units in principal treatment centers (PTCs) across the United Kingdom. The aim of this study was to understand the current cancer patient experience for this patient group. We aimed to determine whether treatment experience is influenced by place of treatment and whether it has changed over time using patient-reported data from national cancer patient experience surveys. This study highlights that a prolonged pathway to diagnosis remains an issue for the TYA group and identifies areas on which quality improvement measures for TYA services should focus, including communication and involvement of the patient in treatment decisions. Positive experiences for the TYA group such as involvement in research were also highlighted. Treatment within a TYA PTC was associated with positive patient perception in a number of key areas highlighting the need for future studies to fully elucidate the impact of the full range of TYA services now available in the United Kingdom on both patient experience and outcome.

  4. Ten-dimensional Supergravity Revisited

    NARCIS (Netherlands)

    Bergshoeff, Eric; Roo, Mees de; Kerstan, Sven; Riccioni, Fabio; Diaz Alonso, J.; Mornas, L.

    2006-01-01

    We show that the exisiting supergravity theories in ten dimensions can be extended with extra gauge fields whose rank is equal to the spacetime dimension. These gauge fields have vanishing field strength but nevertheless play an important role in the coupling of supergravity to spacetime filling

  5. Ten Problems in Experimental Mathematics

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, David H.; Borwein, Jonathan M.; Kapoor, Vishaal; Weisstein, Eric

    2004-09-30

    This article was stimulated by the recent SIAM ''100 DigitChallenge'' of Nick Trefethen, beautifully described in a recent book. Indeed, these ten numeric challenge problems are also listed in a recent book by two of present authors, where they are followed by the ten symbolic/numeric challenge problems that are discussed in this article. Our intent was to present ten problems that are characteristic of the sorts of problems that commonly arise in ''experimental mathematics''. The challenge in each case is to obtain a high precision numeric evaluation of the quantity, and then, if possible, to obtain a symbolic answer, ideally one with proof. Our goal in this article is to provide solutions to these ten problems, and in the process present a concise account of how one combines symbolic and numeric computation, which may be termed ''hybrid computation'', in the process of mathematical discovery.

  6. Understanding Scale: Powers of Ten

    Science.gov (United States)

    Jones, M. Gail; Taylor, Amy; Minogue, James; Broadwell, Bethany; Wiebe, Eric; Carter, Glenda

    2007-01-01

    The classic film "Powers of Ten" is often employed to catalyze the building of more accurate conceptions of scale, yet its effectiveness is largely unknown. This study examines the impact of the film on students' concepts of size and scale. Twenty-two middle school students and six science teachers participated. Students completed pre- and…

  7. A Ten-Year Reflection

    Science.gov (United States)

    Phillip, Cyndi

    2016-01-01

    Five initiatives launched during Cyndi Phillip's term as American Association of School Librarians (AASL) President (2006-2007) continue to have an impact on school librarians ten years later. They include the rewriting of AASL's learning standards, introduction of the SKILLS Act, the presentation of the Crystal Apple Award to Scholastic Library…

  8. Ten Rules of Academic Writing

    NARCIS (Netherlands)

    Donovan, S.K.

    2011-01-01

    Creative writers are well served with 'how to' guides, but just how much do they help? And how might they be relevant to academic authors? A recent survey of writing tips by twenty-eight creative authors has been condensed to the ten most relevant to the academic, supported by some comments on

  9. Ten "Discoveries" About Basic Learning

    Science.gov (United States)

    English, Raymond

    1977-01-01

    Ten conclusions about childrens' learning are presented from 15 years of research by the Educational Research Council of America. These include effectiveness of short textbooks, interest in learning technical words, need for social science curriculum to challenge, and detrimental effect of ingrained teacher attitudes to teach social studies by…

  10. Ten past and ten future GAS/MAUS-payloads

    Science.gov (United States)

    Staniek, S.; Otto, G.; Doepkess, J.

    1988-01-01

    MAUS (materials science autonomous experiments) is one out of a series of flight opportunities which the Space Program of West Germany offers to scientists from the disciplines of materials research and processing for performing materials science investigations under microgravity conditions. Up to now, ten MAUS experiments were flown which were dealing with the following scientific topics: decomposition of binary alloys with miscibility gap in the liquid state, interaction of a solidification front with dispersed particles, critical Marangoni number, investigation of the magnetic compound MnBi, shrinkage of gas bubbles in glass melts and slip casting. The ten future experiments are partly reflights with modification of the scientific objectives as well as new experiments in the fields of chemical reactions, heat transfer, glass technology and Ostwald ripening. Looking to ten flown payloads, the peculiarities of instrument technology in GAS-cans and its evolution is discussed with emphasis on structure, electronics and thermal design. A typical modern payload using 100 percent of the resource is presented.

  11. Secret-key certificates (continued)

    NARCIS (Netherlands)

    S.A. Brands (Stefan)

    1995-01-01

    textabstractA new construction is described for designing secret-key certificate schemes based on signature schemes other than of the Fiat-Shamir type. Also described are practical secret-key certificate issuing protocols that enable the Certification Authority to certify public keys, without being

  12. Foothills Model Forest: a ten-year review

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, R.

    2002-04-01

    The first ten years of the Foothills Model Forest, established in 1992, is reviewed. The model forest has been established to develop sustainable forest management within the broader concept of sustainable development and integrated resource management. The project focuses on issues such as wildlife habits and habitats; biodiversity monitoring; natural disturbance trends and patterns; and socio-economic studies. In Phase One of the Canadian Model Forest Network the Foothills Model Forest focused primarily on conducting world class research to advance the concept of sustainable forest management. Phase Two was devoted to communicating the results of that research, with a strong emphasis on generating baseline awareness of the concept of sustainable forest management and creating public awareness of the project's mandate in Alberta. Work during the next five years is expected to focus on demonstration and implementation of research results to forest managers and practitioners and others with a stake in the continued sustainability of Alberta's forests. The Sustainable Forest Management project shares a common objective with the Alberta Chamber of Resources' Integrated Landscape Management project; both projects recognise that reducing the industrial footprint is key to sustainable development. The emphasis on demonstration and implementation in the third phase of the Foothills Model Forest is expected to ensure continued sustainability of forests, ecosystems, communities and resources, with full recognition of the fact that the goal of sustainable development can be achieved only by full cooperation and integrated action of all stakeholders.

  13. Key Nutrients.

    Science.gov (United States)

    Federal Extension Service (USDA), Washington, DC.

    Lessons written to help trainer agents prepare aides for work with families in the Food and Nutrition Program are presented in this booklet. The key nutrients discussed in the 10 lessons are protein, carbohydrates, fat, calcium, iron, iodine, and Vitamins A, B, C, and D. the format of each lesson is as follows: Purpose, Presentation, Application…

  14. Ten questions about radiant heating and cooling systems

    DEFF Research Database (Denmark)

    Rhee, Kyu-Nam; Olesen, Bjarne W.; Kim, Kwang Woo

    2017-01-01

    to extend the applicability of the RHC system are providing the continuous impetus for research on RHC systems. This paper summarizes the important issues involved in the research on RHC system, whereby ten questions and answers concerning the RHC system are discussed, which will help researchers to conduct...

  15. Ten questions about systems biology

    DEFF Research Database (Denmark)

    Joyner, Michael J; Pedersen, Bente K

    2011-01-01

    In this paper we raise 'ten questions' broadly related to 'omics', the term systems biology, and why the new biology has failed to deliver major therapeutic advances for many common diseases, especially diabetes and cardiovascular disease. We argue that a fundamentally narrow and reductionist...... to understand how whole animals adapt to the real world. We argue that a lack of fluency in these concepts is a major stumbling block for what has been narrowly defined as 'systems biology' by some of its leading advocates. We also point out that it is a failure of regulation at multiple levels that causes many...

  16. Ten questions about systems biology

    DEFF Research Database (Denmark)

    Joyner, Michael J; Pedersen, Bente K

    2011-01-01

    to understand how whole animals adapt to the real world. We argue that a lack of fluency in these concepts is a major stumbling block for what has been narrowly defined as 'systems biology' by some of its leading advocates. We also point out that it is a failure of regulation at multiple levels that causes many......In this paper we raise 'ten questions' broadly related to 'omics', the term systems biology, and why the new biology has failed to deliver major therapeutic advances for many common diseases, especially diabetes and cardiovascular disease. We argue that a fundamentally narrow and reductionist...

  17. Ten Blue Links on Mars

    OpenAIRE

    Clarke, Charles L. A.; Cormack, Gordon V.; Lin, Jimmy; Roegiest, Adam

    2016-01-01

    This paper explores a simple question: How would we provide a high-quality search experience on Mars, where the fundamental physical limit is speed-of-light propagation delays on the order of tens of minutes? On Earth, users are accustomed to nearly instantaneous response times from search engines. Is it possible to overcome orders-of-magnitude longer latency to provide a tolerable user experience on Mars? In this paper, we formulate the searching from Mars problem as a tradeoff between "effo...

  18. Ten Thousand Years of Solitude

    Energy Technology Data Exchange (ETDEWEB)

    Benford, G. (Los Alamos National Lab., NM (USA) California Univ., Irvine, CA (USA). Dept. of Physics); Kirkwood, C.W. (Los Alamos National Lab., NM (USA) Arizona State Univ., Tempe, AZ (USA). Coll. of Business Administration); Harry, O. (Los Alamos National Lab., NM (USA)); Pasqualetti, M.J. (Los Alamos National Lab., NM (USA) Arizona State Univ., Tempe, AZ (USA))

    1991-03-01

    This report documents the authors work as an expert team advising the US Department of Energy on modes of inadvertent intrusion over the next 10,000 years into the Waste Isolation Pilot Project (WIPP) nuclear waste repository. Credible types of potential future accidental intrusion into the WIPP are estimated as a basis for creating warning markers to prevent inadvertent intrusion. A six-step process is used to structure possible scenarios for such intrusion, and it is concluded that the probability of inadvertent intrusion into the WIPP repository over the next ten thousand years lies between one and twenty-five percent. 3 figs., 5 tabs.

  19. Zastosowanie elektroterapii TENS w łagodzeniu bólu porodowego / Application of TENS electrotherapy in alleviating labour pain

    Directory of Open Access Journals (Sweden)

    Sowa Magdalena

    2016-06-01

    Full Text Available Introduction. Easing labour pain is an extremely important issue in obstetric practice. Various physiotherapy methods are increasingly often applied in obstetric practice. Transcutaneous electric nerve stimulation (TENS aiming at central and peripheral modulation of pain sensation is one of them.

  20. Flexibility in faculty work-life policies at medical schools in the Big Ten conference.

    Science.gov (United States)

    Welch, Julie L; Wiehe, Sarah E; Palmer-Smith, Victoria; Dankoski, Mary E

    2011-05-01

    Women lag behind men in several key academic indicators, such as advancement, retention, and securing leadership positions. Although reasons for these disparities are multifactorial, policies that do not support work-life integration contribute to the problem. The objective of this descriptive study was to compare the faculty work-life policies among medical schools in the Big Ten conference. Each institution's website was accessed in order to assess its work-life policies in the following areas: maternity leave, paternity leave, adoption leave, extension of probationary period, part-time appointments, part-time benefits (specifically health insurance), child care options, and lactation policy. Institutions were sent requests to validate the online data and supply additional information if needed. Each institution received an overall score and subscale scores for family leave policies and part-time issues. Data were verified by the human resources office at 8 of the 10 schools. Work-life policies varied among Big Ten schools, with total scores between 9.25 and 13.5 (possible score: 0-21; higher scores indicate greater flexibility). Subscores were not consistently high or low within schools. Comparing the flexibility of faculty work-life policies in relation to other schools will help raise awareness of these issues and promote more progressive policies among less progressive schools. Ultimately, flexible policies will lead to greater equity and institutional cultures that are conducive to recruiting, retaining, and advancing diverse faculty.

  1. Model or measurements? A discussion of the key issue in Chapman and Pollack's critique of Hamza et al.'s re-evaluation of oceanic heat flux and the global power

    Science.gov (United States)

    Hofmeister, Anne M.; Criss, Robert E.

    2008-04-01

    Chapman and Pollack (C and P)[2007, Int J Earth Sci] criticize Hamza et al. [2007, Int J Earth Sci] for using actual heat flux measurements in young oceanic crust instead of values from 1-D cooling models. The rationalization of C and P and previous authors is that hydrothermal circulation causes the discrepancy between model and measurement. However, the discrepancy between model values and measured heat flux exists over the entire ocean floor and is opposite to the perturbations that hydrothermal circulation would superimpose on a conductive system [Hofmeister and Criss (2005) Tectonophysics 409:199 203]. The error lies in force-fitting a 1-D cooling model to the 3-D oceanic crust [Hofmeister and Criss (2005) Tectonophysics 395:159 177]. Shortcomings of the 1-D model include mathematical errors, such as use of volumetric rather than linear thermal expansivity to describe contraction which, by assumption, is limited only to the Z -direction [Hofmeister and Criss (2006) Tectonophysics]. This 3× error, traceable to McKenzie and Sclater [1969, Bull Vocanol 33 1:101 118], accidentally provides good agreement of model values with globally averaged seafloor depths for young, but not old ages, and is the sole rationale for using the simplistic cooling model. There is no justification for selective substitution of erroneous 1-D model values for measurements only for the younger half of the 3-D oceanic crust, as stridently and arbitrarily promoted by C and P. Hamza et al. [2007, Int J Earth Sci], in contrast, use the scientific method, which calls for discarding models that do not well describe physical phenomena. The remainder of this report summarizes the shortcomings of cooling models, particularly the half-space cooling (HSC) model touted by C and P, and explains how hydrothermal circulation affects heat flux. We focus on the basics, as these have been misunderstood. With the key issues of C and P being erroneous, it is not necessary to address their remaining

  2. Grids: The Top Ten Questions

    Directory of Open Access Journals (Sweden)

    Jennifer M. Schopf

    2002-01-01

    Full Text Available The design and implementation of a national computing system and data grid has become a reachable goal from both the computer science and computational science point of view. A distributed infrastructure capable of sophisticated computational functions can bring many benefits to scientific work, but poses many challenges, both technical and socio-political. Technical challenges include having basic software tools, higher-level services, functioning and pervasive security, and standards, while socio-political issues include building a user community, adding incentives for sites to be part of a user-centric environment, and educating funding sources about the needs of this community. This paper details the areas relating to Grid research that we feel still need to be addressed to fully leverage the advantages of the Grid.

  3. Ten years for the public Web

    CERN Multimedia

    2003-01-01

    Ten years ago, CERN issued a statement declaring that a little known piece of software called the World Wide Web was in the public domain. Nowadays, the Web is an indispensable part of modern communications. The idea for the Web goes back to March 1989 when CERN Computer scientist Tim Berners-Lee wrote a proposal for a 'Distributed Information Management System' for the high-energy physics community. The Web was originaly conceived and developed to meet the demand for information sharing between scientists working all over the world. There were many obstacles in the 1980s to the effective exchange of information. There was, for example a great variety of computer and network systems, with hardly any common features. The main purpose of the web was to allow scientists to access information from any source in a consistent and simple way. By Christmas 1990, Berners-Lee's idea had become the World Wide Web, with its first server and browser running at CERN. Through 1991, the Web spread to other particle physics ...

  4. The origin of the future ten questions for the next ten years

    CERN Document Server

    Gribbin, John

    2006-01-01

    How did the universe begin? Where do galaxies come from? How do stars and planets form? Where do the material particles we are made of come from? How did life begin? Today we have only provisional answers to such questions. But scientific progress will improve these answers dramatically over the next ten years, predicts John Gribbin in this riveting book. He focuses on what we know—or think we know—about ten controversial, unanswered issues in the physical sciences and explains how current cutting-edge research may yield solutions in the very near future. With his trademark facility for engaging readers with or without a scientific background, the author explores ideas concerning the creation of the universe, the possibility of other forms of life, and the fate of the expanding cosmos. He examines “theories of everything,” including grand unified theories and string theory, and he discusses the Big Bang theory, the origin of structure and patterns of matter in the galaxies, and dark mass and dark ene...

  5. Design and modeling of inductors, capacitors and coplanar waveguides at tens of GHz frequencies

    CERN Document Server

    Aryan, Naser Pour

    2015-01-01

    This book describes the basic principles of designing and modelling inductors, MIM capacitors and coplanar waveguides at frequencies of several tens of GHz. The author explains the design and modelling of key, passive elements, such as capacitors, inductors and transmission lines that enable high frequency MEMS operating at frequencies in the orders of tens of GHz.

  6. [Contact dermatitis from polyacrylate in TENS electrode].

    Science.gov (United States)

    Weber-Muller, F; Reichert-Penetrat, S; Schmutz, J-L; Barbaud, A

    2004-05-01

    Transcutaneous electric nerve stimulation (TENS) is useful for many chronic pains. It induces few serious side effects, but skin reactions are not rare. We report on two cases of contact dermatitis due to TENS electrodes by sensitization to the acrylate in TENS conductive gel. A 50 year-old man suffered from post-traumatic lumbar pair. He developed eczematous lesions on the sites where the TENS electrodes were applied. Patch tests were positive with the TENS gel, with ethylene glycol dimethylacrylate (2 p. 100 petrolatum) and ethyl-acrylate (2 p. 100 petrolatum) on day 2 and 4 readings. A 54 Year-old man had a paralysis of the foot elevator following rupture of an aneurysm. After 2 months, he had an eczema on the sites where the TENS electrodes were applied. Patch tests were negative with the TENS electrodes but positive with 2-hydroxyethyl acrylate (0.1 p. 100 petrolatum), triethyleneglycol diacrylate (0.1 p. 100 petrolatum), 2-hydroxyethyl methacrylate (2 p. 100 petrolatum) and 2-hydroxypropyl methacrylate (2 p. 100 petrolatum) on day 2 and 4 readings. TENS transmits small electrical currents through the skin that induce the depolarization of the affected sensory nerve endings. They have few serious side effects but skin reactions such as irritation, burns or allergy to propylene glycol in the electrode gel, to the rubber of the electrodes (mercaptobenzothiazole) or to the metallic part of the electrodes, i.e. nickel, are not uncommon. To our knowledge, only one case of an allergy to the polyacrylates of TENS electrode gel has been previously reported in the literature. We emphasize that acrylate could be the main sensitizer in the more recently commercialized TENS electrodes and will propose alternative ways of treating patients sensitized to acrylate and who require treatment with TENS.

  7. JPRS Report Environmental Issues.

    Science.gov (United States)

    1990-05-30

    JPRS-TEN-90-003 30 MAY 1990, FOREIGN BROADcAST INFORMATION SERVICE .PRS Report--- Environmental Issues REPRODUCED BY U.S. DEPARTMENT OF COMMERCE...NATIONAL TECHNICAL INFORMATION SERVICE SPRINGFIELD, VA. 22161 19980203 238 DIS1JýTION S~rTEMfý A Approved for pulic release,Us.ibullon UnZnited L;•;,, i...Plan Outlined [EL COMERCIO 29 Apr] ........... 32 GUATEMALA Workshop Views Environmental Initiatives, Deforestation Rate [DIARIO DE CENTRO AM ERICA 11

  8. Top ten most accessed AMOR articles in 2015/2016

    Directory of Open Access Journals (Sweden)

    Editorial Office

    2016-12-01

    Full Text Available In 2015/2016, Advances in Modern Oncology Research published a total of 67 articles over eight issues in two separate volumes. These published articles, consisting of editorials, reviews, case reports, and original research, have collectively accumulated 26,320 views as of December 2016. A total of 54 authors and 160 peer-reviewers from across the globe contributed to the journal in its first full year of publication. The journal’s top ten most accessed articles are:1. Indoles as anticancer agents (Vol. 1 Issue 1 2. Pharmacometrics and systems pharmacology of immune checkpoint inhibitor nivolumab in cancer translational medicine (Vol. 2 Issue 1 3. Hepatocellular carcinoma (HCC; aetiological considerations (Vol. 1 Issue 1 4. Oligoadenylate synthetase 1 (OAS1 expression in human breast and prostate cancer cases, and its regulation by sex steroid hormones (Vol. 2 Issue 2 5. Antiproliferative effects of cembranoid derivatives obtained from Red Sea soft coral Sarcophyton glaucum on human colorectal cancer cell lines (Vol. 1 Issue 1 6. Paraneoplastic pemphigus: A trait d’union between dermatology and oncology (Vol. 1 Issue 2 7. Cancer cell metastasis; perspectives from the focal adhesion (Vol. 1 Issue 1 8. Threshold-based parametric analysis of diffusion-weighted magnetic resonance imaging at 3.0 Tesla to identify men with prostate cancer (Vol. 1 Issue 2 9. Economic burden of patients with inoperable advanced breast cancer receiving early or late capecitabine or trastuzumab as second-line treatment: A population-based study (Vol. 1 Issue 2 10. Non-coding RNAs: New therapeutic targets and opportunities for hepatocellular carcinoma (Vol. 2 Issue 1

  9. Clinical experience with TENS and TENS combined with nitrous oxide-oxygen. Report of 371 patients.

    OpenAIRE

    Quarnstrom, F. C.; Milgrom, P.

    1989-01-01

    Transcutaneous electrical nerve stimulation (TENS) alone or TENS combined with nitrous oxide-oxygen (N2O) was administered for restorative dentistry without local anesthesia to 371 adult patients. A total of 55% of TENS alone and 84% of TENS/N2O visits were rated successful. A total of 53% of TENS alone and 82% of TENS/N2O patients reported slight or no pain. In multivariable analyses, pain reports were related to the anesthesia technique and patient fear and unrelated to sex, race, age, toot...

  10. Key issues affecting quality of life and patient-reported outcomes in prostate cancer: an analysis conducted in 2128 patients with initial psychometric assessment of the prostate cancer symptom scale (PCSS).

    Science.gov (United States)

    Msaouel, Pavlos; Gralla, Richard J; Jones, Randy A; Hollen, Patricia J

    2017-09-01

    Evidence-based quality of life (QL) questionnaires require the identification of issues of importance to patients. The primary aim of this study was to inform providers on patient-expressed issues while enhancing the content validity of instruments assessing QL and patient-reported outcomes (PROs) in prostate cancer. The study provided additional psychometric properties for the new PRO and QL instrument, the Prostate Cancer Symptom Scale (PCSS). An anonymous web-based survey of 2128 patients with prostate cancer was conducted with patients rating 18 QL items on a five-point scale. Most respondents (74%) were aged 55-74 years, had early stage disease at diagnosis (81%) and were diagnosed within 2 years of the survey (81%). The top five-rated issues were: overall QL, ability to perform normal activities, maintaining independence, ability to sleep and not being a burden. These items were ranked as either 'very important' or 'important' by at least 88% of patients. None of the most highly ranked issues were symptoms. Instead, the highest ranked items were global issues reflecting the impact of symptoms on patients. In addition to the enhanced content validity findings, good reliability results and initial support for construct validity are reported for the PCSS. This is the largest survey providing patient-expressed background for content validity for QL and PRO measures. The findings of this study should aid development of newer practical questionnaires, such as the PCSS, which can be adapted to electronic platforms enhancing rapid and accurate PRO and QL evaluation. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  11. Quality of Life in South Africa--The First Ten Years of Democracy

    Science.gov (United States)

    Moller, Valerie

    2007-01-01

    South Africa celebrated ten years of democracy in 2004. This special issue of "Social Indicators Research" ("SIR") reviews developments that have impacted on the quality of life of ordinary South Africans during the transition period. The issue updates an earlier volume of "SIR" (Volume 41) published in 1997 and as a…

  12. Ten new species of Afrotropical Pterophoridae (Lepidoptera)

    NARCIS (Netherlands)

    Gielis, C.

    2008-01-01

    Ten new Afrotropical species of Pterophoridae are described: Agdistis linnaei spec. nov., Agdistis bouyeri spec. nov., Ochyrotica bjoernstadti spec. nov., Platyptilia aarviki spec. nov., Stenoptilia kiitulo spec. nov., Exelastis caroli spec. nov., Eucapperia continentalis spec. nov., Buckleria

  13. BIOPROTA: Key issues in biosphere aspects of assessment of the long-term impact of contaminant releases associated with radioactive waste management. Theme 2 Task 1: Model review and comparison for spray irrigation pathway

    Energy Technology Data Exchange (ETDEWEB)

    Bergstroem, U.; Albrecht, A.; Kanyar, B.; Smith, G.; Thorne, M.C.; Yoshida, H.; Wasiolek, M.

    2006-04-15

    The objective of Task 1 within Theme 2 was to investigate the modelling of the concentrations of radionuclides on vegetation arising from interception by growing crops using contaminated irrigation water and the consequent contamination of the food consumed by humans. This Task 1 report includes model descriptions provided by participants and the specification and results of model test calculations designed to investigate the significance of the different model assumptions. A significant array of modelling methods has been presented and explained. The equations used and the data adopted have also been presented. This compilation may be useful for future reference. Although the methods vary, most assessment results are within a factor of ten of each other. This is not a large range given the generic nature of the assessment question asked. This is generally due to compensating effects. For example, a high initial assumed retention factor is compensated for when weathering and translocation are then taken into account. That is to say, while different modelling approaches are taken, each conceptual model is internally consistent. Overall, the results lend considerable confidence to the assessment community's ability to assess doses as a result of food contamination due to the direct effects of irrigation. The biggest reasons for discrepancies in results are associated with the treatment of weathering and translocation, post deposition. Values for translocation vary considerably between the participants and there are different interpretations of weathering and translocation data. Another significant reason for differences in models and in results concerns the different irrigation practices used in different areas. These are largely climate driven. Overall it appears that relatively simple models provide very similar results to the more process orientated and data demanding models. Further consideration of the adequacy of the data for assessment purposes will

  14. Implementation fidelity of self-administered transcutaneous electrical nerve stimulation (TENS) in patients with chronic back pain: an observational study.

    Science.gov (United States)

    Pallett, Edward J; Rentowl, Patricia; Johnson, Mark I; Watson, Paul J

    2014-03-01

    The efficacy of transcutaneous electrical nerve stimulation (TENS) for pain relief has not been reliably established. Inconclusive findings could be due to inadequate TENS delivery and inappropriate outcome assessment. Electronic monitoring devices were used to determine patient compliance with a TENS intervention and outcome assessment protocol, to record pain scores before, during, and after TENS, and measure electrical output settings. Patients with chronic back pain consented to use TENS daily for 2 weeks and to report pain scores before, during, and after 1-hour treatments. A ≥ 30% reduction in pain scores was used to classify participants as TENS responders. Electronic monitoring devices "TLOG" and "TSCORE" recorded time and duration of TENS use, electrical settings, and pain scores. Forty-two patients consented to participate. One of 35 (3%) patients adhered completely to the TENS use and pain score reporting protocol. Fourteen of 33 (42%) were TENS responders according to electronic pain score data. Analgesia onset occurred within 30 to 60 minutes for 13/14 (93%) responders. It was not possible to correlate TENS amplitude, frequency, or pulse width measurements with therapeutic response. Findings from TENS research studies depend on the timing of outcome assessment; pain should be recorded during stimulation. TENS device sophistication might be an issue and parameter restriction should be considered. Careful protocol design is required to improve adherence and monitoring is necessary to evaluate the validity of findings. This observational study provides objective evidence to support concerns about poor implementation fidelity in TENS research.

  15. PREVALENCE OF TEN CORAL DISEASES IN THE FLORIDA KEYS AND DRY TORTUGAS

    Science.gov (United States)

    Presented at the 30th Scientific Meeting of the Association of Marine Laboratories of the Carribean-AMLC, 24-29 June 2001, University of Puerto Rico, La Parguera, Puerto Rico. 1 p.More than 14 disease conditions affecting Western Atlantic corals have been reported in the...

  16. Edoxaban in Atrial Fibrillation and Venous Thromboembolism-Ten Key Questions and Answers: A Practical Guide.

    Science.gov (United States)

    De Caterina, Raffaele; Ageno, Walter; Boriani, Giuseppe; Colonna, Paolo; Ghirarduzzi, Angelo; Patti, Giuseppe; Rossini, Roberta; Rubboli, Andrea; Schinco, Piercarla; Agnelli, Giancarlo

    2017-03-01

    Edoxaban is the fourth non-vitamin K antagonist oral anticoagulant now available for clinical use in the prevention of stroke/systemic embolism in atrial fibrillation (AF) and in the treatment of venous thromboembolism (VTE), after the completion of large-scale randomized comparative clinical trials with the vitamin K antagonist warfarin. Edoxaban has some peculiar pharmacological properties and outcome data. Here a group of experts in AF and VTE answers a set of questions on its practical use, trying to define the profile of patients that would be most appropriate for its use.

  17. Ten major trends now emerging in the United States

    Energy Technology Data Exchange (ETDEWEB)

    Naisbitt, J.

    1978-01-01

    Using a special analytical procedure for tracking and assessing events reported in the nation's newspapers, the Center for Policy Process has identified ten emerging trends in the United States that are having a major impact on all our lives and on all businesses and industries--and especially on the electric utility industry. Although the trends may move in contradictory directions and have different degrees of significance, all have been carefully monitored for a considerable length of time. All are firmly established--and are not to be viewed as the momentary interests of certain radical elements of the population. The ten trends are: the fast-emerging clash between nuclear fuel and coal as an environmental health issue; displacement of racism and sexism by ''ageism'' as society's most prominent anti-discrimination preoccupation, and the complete elimination soon of mandatory retirement; in government and technology, the phenomenon of ''appropriate scale'' replacing economies of scale, emergence of single-issue political organizations; coming-of-age of the recycling ethic; emergence of ''access to capital'' as the new equity issue--the new rights issue; continuing shift from centralization to decentralization; movement of society in the dual directions of high technology/high touch; business' increasing involvement with the well-established accountability trend; and shift from a representative democracy to a participatory democracy--this profound change in American democracy actually began about a decade or so ago.

  18. Contemporary Issues in Mentoring.

    Science.gov (United States)

    Grossman, Jean Baldwin, Ed.

    This document contains six papers exploring contemporary issues in mentoring. "The Practice, Quality, and Cost of Mentoring" (Jean Baldwin Grossman) provides an introduction to and overview of the remaining five papers. "Mentoring Adolescents: What Have We Learned?" (Cynthia L. Sipe) reviews the literature on mentoring, discusses key elements in…

  19. Transcutaneous electric nerve stimulation (TENS) for cancer pain in adults.

    Science.gov (United States)

    Hurlow, Adam; Bennett, Michael I; Robb, Karen A; Johnson, Mark I; Simpson, Karen H; Oxberry, Stephen G

    2012-03-14

    Cancer-related pain is complex and multi-dimensional but the mainstay of cancer pain management has predominantly used a biomedical approach. There is a need for non-pharmacological and innovative approaches. Transcutaneous Electric Nerve Stimulation (TENS) may have a role in pain management but the effectiveness of TENS is currently unknown. This is an update of the original review published in Issue 3, 2008. The aim of this systematic review was to determine the effectiveness of TENS for cancer-related pain in adults. The initial review searched The Cochrane Library, MEDLINE, EMBASE, CINAHL, PsychINFO, AMED and PEDRO databases in April 2008. We performed an updated search of CENTRAL, MEDLINE, EMBASE, CINAHL and PEDRO databases in November 2011. We included only randomised controlled trials (RCTS) investigating the use of TENS for the management of cancer-related pain in adults. The search strategy identified a further two studies for possible inclusion. One of the review authors screened each abstract using a study eligibility tool. Where eligibility could not be determined, a second author assessed the full paper. One author used a standardised data extraction sheet to collect information on the studies and independently assess the quality of the studies using the validated five-point Oxford Quality Scale. The small sample sizes and differences in patient study populations of the three included studies (two from the original review and a third included in this update) prevented meta-analysis. For the original review the search strategy identified 37 possible published studies; we divided these between two pairs of review authors who decided on study selection; all four review authors discussed and agreed final scores. Only one additional RCT met the eligibility criteria (24 participants) for this updated review. Although this was a feasibility study, not designed to investigate intervention effect, it suggested that TENS may improve bone pain on movement in a

  20. Development and characterization of ten polymorphic microsatellites ...

    Indian Academy of Sciences (India)

    Quililongo C. J., Ríos-Ramírez M. A., Velásquez-Cumplido L., Morales-Muñoz B. and Escobar-Fica J. A. 2012 Development and characterization of ten polymorphic microsatellites isolated from the scallop Argopecten purpuratus. J. Genet.

  1. Ten-year urban forestry action plan

    Science.gov (United States)

    J.W." Jerry" Van Sambeek

    2017-01-01

    The Ten-year Urban Forestry Action Plan: 2016-2026 was published in September, 2015 (see http://www.urbanforestry.subr.edu/FinalActionPlan_Complete_11_17_15.pdf). This 260 page heavily illustrated document was prepared by the National Urban and Community Forestry Advisory Council (NUCFAC) under leadership and funding from the USDA Forest Service. The Plan's...

  2. UTILITY OF THE TEN PER CENT RULE

    African Journals Online (AJOL)

    2001-11-01

    Nov 1, 2001 ... Objective: To measure asymmetry in grip strength between hands in left, right and mixed handers and to test utility of the ten per cent rule. Design: A cross sectional study. Setting: Queen Elizabeth Central Hospital, Blantyre, Malawi. Subjects: One hundred and seventy six healthy volunteers (102 males and ...

  3. Strahlungsfelder und Strahlungsqualitäten

    Science.gov (United States)

    Krieger, Hanno

    Das Kapitel beginnt mit einer Darstellung der wichtigsten Größen zur Beschreibung von Strahlungsfeldern. Diese Größen können sowohl auf die Teilchenzahl als auch auf die Teilchenenergie bezogen sein. Im zweiten Teil werden ausführlich die Verfahren zur Charakterisierung der Strahlungsqualitäten der verschiedenen in der Radiologie verwendeten Strahlungsarten dargestellt.

  4. Ten recommendations for software engineering in research.

    Science.gov (United States)

    Hastings, Janna; Haug, Kenneth; Steinbeck, Christoph

    2014-01-01

    Research in the context of data-driven science requires a backbone of well-written software, but scientific researchers are typically not trained at length in software engineering, the principles for creating better software products. To address this gap, in particular for young researchers new to programming, we give ten recommendations to ensure the usability, sustainability and practicality of research software.

  5. CRUDE PROTEIN ELECTROPHORESIS OF SEEDS OF TEN

    African Journals Online (AJOL)

    A A Essiett

    Seeds of mature fruits of ten species of Solanum were collected from the gardens near the screen house, Botany. Department, Obafemi Awolowo University, Ile Ife, Osun State, Nigeria. Crude seed proteins were extracted from them and characterised using polyacrylamide gel electrophoresis. Inter and intra specific ...

  6. (CdnTen) and Cadmium Zinc Telluride

    African Journals Online (AJOL)

    Bheema

    solar cells, integrated optics and electro-optics devices. Hence, there are different experimental and theoretical studies on this group using various techniques or methods. A number of theoretical and experimental attempts (Jianguang, 2009) have been made to determine the structure and properties of small CdnTen and ...

  7. Czech, Slovak science ten years after split

    CERN Multimedia

    2003-01-01

    Ten years after the split of Czechoslovakia Czech and Slovak science are facing the same difficulties: shortage of money for research, poor salaries, obsolete equipment and brain drain, especially of the young, according to a feature in the Daily Lidove Noviny (1 page).

  8. Exercise Is Key to Healthy Aging

    Science.gov (United States)

    ... on. NIH Research Exercise Is Key to Healthy Aging Past Issues / Winter 2015 Table of Contents Dr. Hodes, Director of the National Institute on Aging, does regular strength training and aerobic exercise. Photo ...

  9. KEY TOPICS IN SPORTS MEDICINE

    OpenAIRE

    Amir Ali Narvani; Panagiotis Thomas; Burce Lynn

    2006-01-01

    Key Topics in Sports Medicine is a single quick reference source for sports and exercise medicine. It presents the essential information from across relevant topic areas, and includes both the core and emerging issues in this rapidly developing field. It covers: 1) Sports injuries, rehabilitation and injury prevention, 2) Exercise physiology, fitness testing and training, 3) Drugs in sport, 4) Exercise and health promotion, 5) Sport and exercise for special and clinical populations, 6) The ps...

  10. Cross-cultural science: ten lessons

    National Research Council Canada - National Science Library

    Horn, Joanne M

    2015-01-01

    Concerns of infectious disease outbreaks have recently reached the forefront of global security issues and resulted in new engagements among foreign science advisors, host country scientists, and officials...

  11. Identification of the Key Fields and Their Key Technical Points of Oncology by Patent Analysis.

    Directory of Open Access Journals (Sweden)

    Ting Zhang

    Full Text Available This paper aims to identify the key fields and their key technical points of oncology by patent analysis.Patents of oncology applied from 2006 to 2012 were searched in the Thomson Innovation database. The key fields and their key technical points were determined by analyzing the Derwent Classification (DC and the International Patent Classification (IPC, respectively. Patent applications in the top ten DC occupied 80% of all the patent applications of oncology, which were the ten fields of oncology to be analyzed. The number of patent applications in these ten fields of oncology was standardized based on patent applications of oncology from 2006 to 2012. For each field, standardization was conducted separately for each of the seven years (2006-2012 and the mean of the seven standardized values was calculated to reflect the relative amount of patent applications in that field; meanwhile, regression analysis using time (year and the standardized values of patent applications in seven years (2006-2012 was conducted so as to evaluate the trend of patent applications in each field. Two-dimensional quadrant analysis, together with the professional knowledge of oncology, was taken into consideration in determining the key fields of oncology. The fields located in the quadrant with high relative amount or increasing trend of patent applications are identified as key ones. By using the same method, the key technical points in each key field were identified. Altogether 116,820 patents of oncology applied from 2006 to 2012 were retrieved, and four key fields with twenty-nine key technical points were identified, including "natural products and polymers" with nine key technical points, "fermentation industry" with twelve ones, "electrical medical equipment" with four ones, and "diagnosis, surgery" with four ones.The results of this study could provide guidance on the development direction of oncology, and also help researchers broaden innovative ideas and

  12. Identification of the Key Fields and Their Key Technical Points of Oncology by Patent Analysis.

    Science.gov (United States)

    Zhang, Ting; Chen, Juan; Jia, Xiaofeng

    2015-01-01

    This paper aims to identify the key fields and their key technical points of oncology by patent analysis. Patents of oncology applied from 2006 to 2012 were searched in the Thomson Innovation database. The key fields and their key technical points were determined by analyzing the Derwent Classification (DC) and the International Patent Classification (IPC), respectively. Patent applications in the top ten DC occupied 80% of all the patent applications of oncology, which were the ten fields of oncology to be analyzed. The number of patent applications in these ten fields of oncology was standardized based on patent applications of oncology from 2006 to 2012. For each field, standardization was conducted separately for each of the seven years (2006-2012) and the mean of the seven standardized values was calculated to reflect the relative amount of patent applications in that field; meanwhile, regression analysis using time (year) and the standardized values of patent applications in seven years (2006-2012) was conducted so as to evaluate the trend of patent applications in each field. Two-dimensional quadrant analysis, together with the professional knowledge of oncology, was taken into consideration in determining the key fields of oncology. The fields located in the quadrant with high relative amount or increasing trend of patent applications are identified as key ones. By using the same method, the key technical points in each key field were identified. Altogether 116,820 patents of oncology applied from 2006 to 2012 were retrieved, and four key fields with twenty-nine key technical points were identified, including "natural products and polymers" with nine key technical points, "fermentation industry" with twelve ones, "electrical medical equipment" with four ones, and "diagnosis, surgery" with four ones. The results of this study could provide guidance on the development direction of oncology, and also help researchers broaden innovative ideas and discover new

  13. Synchronous ten trigger finger: A case report

    Directory of Open Access Journals (Sweden)

    Gokce Yildiran

    2016-08-01

    Full Text Available Trigger finger is a disorder that presents with a blocking feeling and pain during finger movements. This condition more commonly occurs in the 2nd finger with involvement of multiple digits being extremely rare. There are very few known cases in which trigger finger was developed in all ten fingers. Here, an unusual case of ten-digit finger trigger is presented. A 44-year-old female housewife visited our clinic with painful blocking feeling in her hand. Her examination was compatible with trigger finger. Her hands were operated on in different sessions and A1 pulleys of all fingers were released. After the operations, blocking feeling and pain during flexion disappeared and normal range of motion was obtained. On the occasion of this very rare case, the etiology and approach for multiple trigger fingers is discussed. [Hand Microsurg 2016; 5(2.000: 84-87

  14. Compartmentalized expression of zebrafish ten-m3 and ten-m4, homologues of the Drosophila ten(m)/odd Oz gene, in the central nervous system.

    Science.gov (United States)

    Mieda, M; Kikuchi, Y; Hirate, Y; Aoki, M; Okamoto, H

    1999-09-01

    Zebrafish ten-m3 and ten-m4 encode proteins highly similar to the product of Drosophila pair-rule gene ten(m)/odd Oz (odz). Their products contain eight epidermal growth factor (EGF)-like repeats that resemble mostly those of the extracellular matrix molecule tenascin. During segmentation period, ten-m3 is expressed in the somites, notochord, pharyngeal arches, and the brain, while expression of ten-m4 is mainly restricted to the brain. In the developing brain, ten-m3 and ten-m4 expression delineates several compartments. Interestingly, ten-m3 and ten-m4 show expression patterns complementary to each other in the developing forebrain and midbrain along both rostrocaudal and dorsoventral axes, depending on developmental stages and locations.

  15. EEG Correlates of Ten Positive Emotions

    OpenAIRE

    Hu, Xin; Yu, Jianwen; Song, Mengdi; Yu, Chun; Wang, Fei; Sun, Pei; Wang, Daifa; Zhang, Dan

    2017-01-01

    Compared with the well documented neurophysiological findings on negative emotions, much less is known about positive emotions. In the present study, we explored the EEG correlates of ten different positive emotions (joy, gratitude, serenity, interest, hope, pride, amusement, inspiration, awe, and love). A group of 20 participants were invited to watch 30 short film clips with their EEGs simultaneously recorded. Distinct topographical patterns for different positive emotions were found for th...

  16. EEG Correlates of Ten Positive Emotions.

    Science.gov (United States)

    Hu, Xin; Yu, Jianwen; Song, Mengdi; Yu, Chun; Wang, Fei; Sun, Pei; Wang, Daifa; Zhang, Dan

    2017-01-01

    Compared with the well documented neurophysiological findings on negative emotions, much less is known about positive emotions. In the present study, we explored the EEG correlates of ten different positive emotions (joy, gratitude, serenity, interest, hope, pride, amusement, inspiration, awe, and love). A group of 20 participants were invited to watch 30 short film clips with their EEGs simultaneously recorded. Distinct topographical patterns for different positive emotions were found for the correlation coefficients between the subjective ratings on the ten positive emotions per film clip and the corresponding EEG spectral powers in different frequency bands. Based on the similarities of the participants' ratings on the ten positive emotions, these emotions were further clustered into three representative clusters, as 'encouragement' for awe, gratitude, hope, inspiration, pride, 'playfulness' for amusement, joy, interest, and 'harmony' for love, serenity. Using the EEG spectral powers as features, both the binary classification on the higher and lower ratings on these positive emotions and the binary classification between the three positive emotion clusters, achieved accuracies of approximately 80% and above. To our knowledge, our study provides the first piece of evidence on the EEG correlates of different positive emotions.

  17. EEG Correlates of Ten Positive Emotions

    Science.gov (United States)

    Hu, Xin; Yu, Jianwen; Song, Mengdi; Yu, Chun; Wang, Fei; Sun, Pei; Wang, Daifa; Zhang, Dan

    2017-01-01

    Compared with the well documented neurophysiological findings on negative emotions, much less is known about positive emotions. In the present study, we explored the EEG correlates of ten different positive emotions (joy, gratitude, serenity, interest, hope, pride, amusement, inspiration, awe, and love). A group of 20 participants were invited to watch 30 short film clips with their EEGs simultaneously recorded. Distinct topographical patterns for different positive emotions were found for the correlation coefficients between the subjective ratings on the ten positive emotions per film clip and the corresponding EEG spectral powers in different frequency bands. Based on the similarities of the participants’ ratings on the ten positive emotions, these emotions were further clustered into three representative clusters, as ‘encouragement’ for awe, gratitude, hope, inspiration, pride, ‘playfulness’ for amusement, joy, interest, and ‘harmony’ for love, serenity. Using the EEG spectral powers as features, both the binary classification on the higher and lower ratings on these positive emotions and the binary classification between the three positive emotion clusters, achieved accuracies of approximately 80% and above. To our knowledge, our study provides the first piece of evidence on the EEG correlates of different positive emotions. PMID:28184194

  18. Quantum key management

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, Richard John; Thrasher, James Thomas; Nordholt, Jane Elizabeth

    2016-11-29

    Innovations for quantum key management harness quantum communications to form a cryptography system within a public key infrastructure framework. In example implementations, the quantum key management innovations combine quantum key distribution and a quantum identification protocol with a Merkle signature scheme (using Winternitz one-time digital signatures or other one-time digital signatures, and Merkle hash trees) to constitute a cryptography system. More generally, the quantum key management innovations combine quantum key distribution and a quantum identification protocol with a hash-based signature scheme. This provides a secure way to identify, authenticate, verify, and exchange secret cryptographic keys. Features of the quantum key management innovations further include secure enrollment of users with a registration authority, as well as credential checking and revocation with a certificate authority, where the registration authority and/or certificate authority can be part of the same system as a trusted authority for quantum key distribution.

  19. Group key management

    Energy Technology Data Exchange (ETDEWEB)

    Dunigan, T.; Cao, C.

    1997-08-01

    This report describes an architecture and implementation for doing group key management over a data communications network. The architecture describes a protocol for establishing a shared encryption key among an authenticated and authorized collection of network entities. Group access requires one or more authorization certificates. The implementation includes a simple public key and certificate infrastructure. Multicast is used for some of the key management messages. An application programming interface multiplexes key management and user application messages. An implementation using the new IP security protocols is postulated. The architecture is compared with other group key management proposals, and the performance and the limitations of the implementation are described.

  20. Boundary issues

    Science.gov (United States)

    Townsend, Alan R.; Porder, Stephen

    2011-03-01

    What is our point of no return? Caesar proclaimed 'the die is cast' while crossing the Rubicon, but rarely does modern society find so visible a threshold in our continued degradation of ecosystems and the services they provide. Humans have always used their surroundings to make a living— sometimes successfully, sometimes not (Diamond 2005)—and we intuitively know that there are boundaries to our exploitation. But defining these boundaries has been a challenge since Malthus first prophesied that nature would limit the human population (Malthus 1798). In 2009, Rockström and colleagues tried to quantify what the 6.8 billion (and counting) of us could continue to get away with, and what we couldn't (Rockström et al 2009). In selecting ten 'planetary boundaries', the authors contend that a sustainable human enterprise requires treating a number of environmental thresholds as points of no return. They suggest we breach these Rubicons at our own peril, and that we've already crossed three: biodiversity loss, atmospheric CO2, and disruption of the global nitrogen (N) cycle. As they clearly hoped, the very act of setting targets has provoked scientific inquiry about their accuracy, and about the value of hard targets in the first place (Schlesinger 2009). Such debate is a good thing. Despite recent emphasis on the science of human-ecosystem interactions, understanding of our planetary boundaries is still in its infancy, and controversy can speed scientific progress (Engelhardt and Caplan 1987). A few weeks ago in this journal, Carpenter and Bennett (2011) took aim at one of the more controversial boundaries in the Rockström analysis: that for human alteration of the global phosphorus (P) cycle. Rockström's group chose riverine P export as the key indicator, suggesting that humans should not exceed a value that could trigger widespread marine anoxic events—and asserting that we have not yet crossed this threshold. There are defensible reasons for a marine

  1. Special issue of photosynthetic research.

    Science.gov (United States)

    Okamura, Melvin; Wraight, Colin A; van Grondelle, Rienk

    2014-05-01

    This Special Issue of Photosynthesis Research honors Louis M. N. Duysens, Roderick K. Clayton, and George Feher, three pioneering researchers whose work on bacterial photosynthesis laid much of the groundwork for our understanding of the role of the reaction center in photosynthetic light energy conversion. Their key discoveries are briefly summarized and an overview of the special issue is presented.

  2. Inverse statistical physics of protein sequences: a key issues review

    Science.gov (United States)

    Cocco, Simona; Feinauer, Christoph; Figliuzzi, Matteo; Monasson, Rémi; Weigt, Martin

    2018-03-01

    In the course of evolution, proteins undergo important changes in their amino acid sequences, while their three-dimensional folded structure and their biological function remain remarkably conserved. Thanks to modern sequencing techniques, sequence data accumulate at unprecedented pace. This provides large sets of so-called homologous, i.e. evolutionarily related protein sequences, to which methods of inverse statistical physics can be applied. Using sequence data as the basis for the inference of Boltzmann distributions from samples of microscopic configurations or observables, it is possible to extract information about evolutionary constraints and thus protein function and structure. Here we give an overview over some biologically important questions, and how statistical-mechanics inspired modeling approaches can help to answer them. Finally, we discuss some open questions, which we expect to be addressed over the next years.

  3. U.S. Army War College Key Strategic Issues List

    Science.gov (United States)

    2008-07-01

    for ethanol . Research amount of available land for potential sugarcane ethanol production versus national consumption. Determine labor intensity...also changes and growth of civil military relationships). 30. Viability of ethanol production for achieving energy security in CENTAM and select...Caribbean nations (Jamaica, Dominican Republic, Haiti, Barbados). Use open source information to determine if sugar cane ethanol is a better economic

  4. Bahrain: Key Issues for U.S. Policy

    National Research Council Canada - National Science Library

    Katzman, Kenneth

    2005-01-01

    .... naval forces in the Gulf since the end of World War II. In September 2004, the United States and Bahrain signed a free trade agreement to encourage further reform and signal appreciation for Bahrain's support...

  5. U.S. Army War College: Key Strategic Issues List

    Science.gov (United States)

    2006-07-01

    governments that may not support our regional policies (for example, a Cooperative Security Location (CSL) In Manta, Ecuador )? b. What specific role can...sense and respond” logistics in an Enterprise Resource Planning ( ERP ) environment d. The role of the Army’s ground systems industrial base (organic

  6. Key issues in achieving an integrative perspective on stress

    Indian Academy of Sciences (India)

    Madhu Sudhan

    2007-04-02

    Apr 2, 2007 ... undergoes stress, and appreciation that biological phenomena occur at diverse levels of organization (from molecule ..... international scale. Presently the major impediment to the resolution of the three fundamental controversies (above) may not be so much in data acquisition as in analysis and synthesis.

  7. Key issues in theoretical and functional pneumatic design

    Science.gov (United States)

    Xu, Z. G.; Yang, D. Y.; Liu, W. M.; Liu, T. T.

    2017-10-01

    This paper studies the energy release of the pneumatic engine in different thermodynamic processes, the isothermal process is the highest power output process, while adiabatic process is the lowest energy output process, and the energy release of the pneumatic engine is a multi-state thermodynamic process between them. Therefore heat exchanging should be increased between the pneumatic engine and the outer space, the gas expansion process in the cylinder should be as close as possible to the isothermal process. Heat exchange should be increased between the cylinder and the external spaces. Secondly, the fin structure is studied to increase the heat exchanging between the cylinder body and the outside space. The upper part has fin structures and the lower cylinder has no fin structure, this structure improved the working efficiency of pneumatic engine. Finally the cam and the hydraulic bottle of pneumatic engines are designed. Simulation and theoretical calculation are used to the analysis of the whole structure, which lay the foundation for the manufacturing and design of the pneumatic engines.

  8. Key issues for Pan-European rail freight services

    Directory of Open Access Journals (Sweden)

    Tom ZUNDER

    2010-01-01

    Full Text Available The objective of the RETRACK project, funded by the European Commission, is to conduct research to develop, demonstrate and implement a sustainable rail freight service along the East-West corridor (see fig. 1 from Constantza to Rotterdam crossing over the five national railway networks and four border crossing points. The authors have conducted state-of-the-art literature review and field surveys for this project. The current research reports the state-of-the-art of rail freight services along the RETRACK corridor in the areas of transhipment technology and systems, information and communication systems, safety and security of cargo, rolling stock and locomotives, human resources, legislative and regulatory status, and command and control systems. The research finds that all of national networks vary in terms of capabilities, competence and capacities in these areas and that the demonstration of a commercial rail freight service on the corridor will be feasible, competitive, and environmental friendly and will help achieving the long-aspired European Commission’s (EC transport policy of modal shift.

  9. Narrative Research in Communication: Key Principles and Issues

    Directory of Open Access Journals (Sweden)

    Daniel G. McDonald

    2014-01-01

    Full Text Available A great deal of recent research on communication has been developed in the general area of narrative or narrative effects. The majority of this work has brought in older communication concepts without reconciling those concepts with what has been learned about narrative in other social sciences. This review covers some of the major points from research on narrative to help expand the knowledge base and suggest directions for additional work in the field of communication.

  10. working towards an african peacekeeping capability: key issues

    African Journals Online (AJOL)

    Arianne

    deployment was organised on the basis of 'coalitions of the willing'. This said, it seems that the ASF .... to send a special mission to Burundi, the OAU organised a mission on its own. It was able to negotiate, ... consensus of all OAU member states or should a smaller body be responsible for such decision-making?).16 Thus ...

  11. Trade Unions as Organisations: Key Issues and Problems of Internal ...

    African Journals Online (AJOL)

    regulating labour market and Managerial Relations with employees. Similarly, it is the opinion of this article that theoretically speaking and to some extent, Trade Unions adopt democratic constitutions by giving their members ultimate control over certain policy decisions and the organisation of their own union activities.

  12. Village Health Volunteers: Key Issues Facing Agencies in Malawi

    African Journals Online (AJOL)

    cruitment, support and supervision, working conditions, and hours for village health volunteers. There is a sound public health policy established in Malawi although there are not enough trained people (or other resources) to teach, counsel, treat, and motivate the community to good health. It has been shown elsewhere that ...

  13. Comorbidities: a key issue in patients with disorders of consciousness.

    Science.gov (United States)

    Pistoia, Francesca; Sacco, Simona; Franceschini, Marco; Sarà, Marco; Pistarini, Caterina; Cazzulani, Benedetta; Simonelli, Ilaria; Pasqualetti, Patrizio; Carolei, Antonio

    2015-05-15

    The aim of this study was to identify the impact of comorbidities on outcomes of patients with vegetative state (VS) or minimally conscious state (MCS). All patients in VS or MCS consecutively admitted to two postacute care units within a 1-year period were evaluated at baseline and at 6 months through the Coma Recovery Scale-Revised Version and the Disability Rating Scale (DRS). Comorbidities were also recorded for each patient along the same period. Six-month outcomes included death, full recovery of consciousness, and functional improvement. One hundred and thirty-nine patients (88 male and 51 female; median age, 59 years) were included. Ninety-seven patients were in VS (70%) and 42 in MCS (30%). At 6 months, 33 patients were dead (24%), 39 had a full recovery of consciousness (28%), and 67 remained in VS or MCS (48%). According to DRS scores, 40% of patients (n=55) showed a functional improvement in the level of disability. One hundred and thirty patients (94%) showed at least one comorbidity. Severity of comorbidities (hazard ratio [HR]=2.8; 95% confidence interval [CI], 1.71-4.68; pfull recovery of consciousness (odds ratio [OR]=0.3; 95% CI, 0.12-0.7; p=0.006; OR=0.2; 95% CI, 0.07-0.43; pconsciousness and outcomes.

  14. Key issues in successfull tranformations of industral heritage

    NARCIS (Netherlands)

    Scheltens, A; van der Voordt, Theo; Koppels, P.W.; van Dobbelsteen, aajf

    2009-01-01

    Much of our industrial heritage lost its function in the transition from an industrial to a more service-based economy. Meantime, changing consumer preferences have shortened the functional and economic life cycle of buildings to such an extent that many have become vacant and obsolete. Developers

  15. Should we hold the obese responsible? - some key issues.

    Science.gov (United States)

    Nielsen, Morten Ebbe Juul; Andersen, Martin Marchman

    2014-10-01

    It is a common belief that obesity is wholly or partially a question of personal choice and personal responsibility. It is also widely assumed that when individuals are responsible for some unfortunate state of affairs, society bears no burden to compensate them. This article focuses on two conceptualizations of responsibility: backward-looking and forward-looking conceptualizations. When ascertaining responsibility in a backward-looking sense, one has to determine how that state of affairs came into being or where the agent stood in relation to it. In contrast, a forward-looking conceptualization of responsibility puts aside questions of the past and holds a person responsible by reference to some desirable future state of affairs and will typically mean that he or she is subjected to criticism, censure, or other negative appraisals or that he or she is held cost-responsible in some form, for example, in terms of demanded compensation, loss of privileges, or similar. One example of this view is the debate as to whether the obese should be denied, wholly or partially, free and equal access to healthcare, not because they are somehow personally responsible in the backward-looking sense but simply because holding the obese responsible will have positive consequences. Taking these two conceptions of responsibility into account, the authors turn their analysis toward examining the relevant moral considerations to be taken into account when public policies regarding obesity rely on such a conception of responsibility.

  16. Security Issues of the Digital Certificates within Public Key Infrastructures

    National Research Council Canada - National Science Library

    Cristian, TOMA

    2009-01-01

    .... The reasons for byte level analysis are various and important. For instance, a research paper has mentioned how a PKI security may be violated by MD5 collision over information from the certificates...

  17. Polyphenols: Key Issues Involved in Chemoprevention of Prostate Cancer

    Directory of Open Access Journals (Sweden)

    Sebastiano Cimino

    2012-01-01

    Full Text Available Prostate cancer is is the most common solid neoplasm and it is now recognized as one of the most important medical problems facing the male population. Due to its long latency and its identifiable preneoplastic lesions, prostate cancer is an ideal target tumor for chemoprevention. Different compounds are available and certainly polyphenols represent those with efficacy against prostate cancer. This review take a look at activity and properties of major polyphenolic substances, such as epigallocatechin-3-gallate, curcumin, resveratrol and the flavonoids quercetin and genistein. Although the current studies are limited, mechanisms of action of polyphenols added with the lack of side effects show a a start for future strategies in prostate chemoprevention.

  18. Juvenile delinquency in Russia: Ccriminal justice, trends, key issues

    Directory of Open Access Journals (Sweden)

    Kovačević Milica

    2015-01-01

    Full Text Available In the literature, as well as in international statistical surveys, we can rarely find more detailed information on juvenile delinquency in the Russian Federation, as well as on the criminal reaction towards juvenile offenders. Due to the turbulent conditions and great social turmoil which took place in the last few decades in this country, there should be a greater interest in the problem of juvenile delinquency. For Serbia, the experience of the Russian Federation could be especially important if one bears in mind that our country is still going through a transition, population stratification and through economic crisis, and also that Serbia and the Russian Federation share some cultural and religious similarities. Therefore, the aim of this paper is to present, in the summary way, the basic features of juvenile delinquency and the criminal justice system, and thereby build a basis for future research and comparison.

  19. working towards an african peacekeeping capability: key issues

    African Journals Online (AJOL)

    Arianne

    35 D, Ndaba, “Pondering Security and Peace”, Salut 12, 6, 2005, p.35. 36 PANA, “West African Commission Endorses Standing Force”, Panapress, 19 June 2004, www.panapress.com/freenews.asp?code=eng046289&dte=19/06/2004. 37 AFP, “West African Defense Chiefs Establish 'Rapid Reaction Force'“, SpaceWar, ...

  20. Compositional analysis of GM crops: key issues and future needs

    Science.gov (United States)

    Effective symposia need two strong legs to stand upon: informative presentations of recent research paired with lively discussion of these topics. While it is easy for the organizers of a symposium to predict the usefulness of the former, as they select the speakers and their topic areas, guaranteei...

  1. Some key issues in the development of ergonomic intervention tools

    OpenAIRE

    Edwards, Kasper; Winkel, Jørgen

    2016-01-01

    Literature reviews suggest that tools facilitating the ergonomic intervention processes should be integrated into rationalization tools, particular if such tools are participative. Such a Tool has recently been developed as an add-in module to the Lean tool “Value Stream Mapping” (VSM). However, in the investigated context this module seems not to have any direct impact on the generation of proposals with ergonomic consideration. Contextual factors of importance seem to be e.g. allocation of ...

  2. Key issues in achieving an integrative perspective on stress

    Indian Academy of Sciences (India)

    2007-04-02

    Apr 2, 2007 ... Author Affiliations. Martin E Feder1. Department of Organismal Biology and Anatomy, The Committees on Evolutionary Biology, Genetics, and Molecular Medicine, The College, The University of Chicago, 1027 E. 57th Street, Chicago, IL 60637, USA ...

  3. Algal biofuels: key issues, sustainability and life cycle assessment

    DEFF Research Database (Denmark)

    Singh, Anoop; Olsen, Stig Irving

    2011-01-01

    In recent years research activities are intensively focused on renewable fuels in order to fulfill the increasing energy demand and to reduce the fossil fuels consumption and external oil dependency either in order to provide local energetic resources and or as a means for reducing greenhouse gases...... (GHG) emissions to reduce the climate change effects. Among the various renewable energy sources algal biofuels is a very promising source of biomass as algae sequester huge quantities of carbon from atmosphere and are very efficient in utilizing the nutrients from the industrial effluent and municipal...... capital investment. The harvested algal biomass and its extracts can be efficiently converted to different biofuels such as bioethanol, biodiesel, biogas and biohydrogen by implementation of various process technologies. Comprehensive life cycle assessments (LCA) of algal biofuels illustrating...

  4. Liberia's Post-War Recovery: Key Issues and Developments

    National Research Council Canada - National Science Library

    Cook, Nicolas

    2007-01-01

    ...), against two armed anti-Taylor rebel groups. It also destabilized neighboring states, which accepted Liberian refugees and, in some cases, hosted anti-Taylor forces and became targets of the Taylor regime...

  5. Security Issues of the Digital Certificates within Public Key Infrastructures

    Directory of Open Access Journals (Sweden)

    2009-01-01

    Full Text Available The paper presents the basic byte level interpretation of an X.509 v3 digital certificate according to ASN.1 DER/BER encoding. The reasons for byte level analysis are various and important. For instance, a research paper has mentioned how a PKI security may be violated by MD5 collision over information from the certificates. In order to develop further studies on the topic a serious knowledge about certificate structure is necessary.

  6. Algal biofuels: key issues, sustainability and life cycle assessment

    Energy Technology Data Exchange (ETDEWEB)

    Singh, A.; Irving Olsen, S.

    2011-05-15

    In recent years research activities are intensively focused on renewable fuels in order to fulfill the increasing energy demand and to reduce the fossil fuels consumption and external oil dependency either in order to provide local energetic resources and or as a means for reducing greenhouse gases (GHG) emissions to reduce the climate change effects. Among the various renewable energy sources algal biofuels is a very promising source of biomass as algae sequester huge quantities of carbon from atmosphere and are very efficient in utilizing the nutrients from the industrial effluent and municipal wastewater. Algae capture CO{sub 2} from atmosphere and industrial flue gases and transform it in to organic biomass that can be used for the production of biofuels. Like other biomass, algal biomass is also a carbon neutral source for the production of bioenergy. Therefore cultivation of algal biomass provides dual benefits; while being able to utilize nutrients in waste water thus reducing impacts on inland waters it produce biomass for the production of biofuels. However, reaching commercial scale production of algal biofuels is difficult. The main drawbacks include the harvesting of dry biomass and higher capital investment. The harvested algal biomass and its extracts can be efficiently converted to different biofuels such as bioethanol, biodiesel, biogas and biohydrogen by implementation of various process technologies. Comprehensive life cycle assessments (LCA) of algal biofuels illustrating environmental benefits and impacts can be a tool for policy decisions and for technology development. (Author)

  7. Client Centeredness and Health Reform: Key Issues for Occupational Therapy

    Science.gov (United States)

    Pitonyak, Jennifer S.; Fogelberg, Donald; Leland, Natalie E.

    2015-01-01

    Health reform promotes the delivery of patient-centered care. Occupational therapy’s rich history of client-centered theory and practice provides an opportunity for the profession to participate in the evolving discussion about how best to provide care that is truly patient centered. However, the growing emphasis on patient-centered care also poses challenges to occupational therapy’s perspectives on client-centered care. We compare the conceptualizations of client-centered and patient-centered care and describe the current state of measurement of client-centered and patient-centered care. We then discuss implications for occupational therapy’s research agenda, practice, and education within the context of patient-centered care, and propose next steps for the profession. PMID:26356651

  8. Toward Successful School Crisis Intervention: 9 Key Issues

    Science.gov (United States)

    Jaksec, Charles M., III

    2007-01-01

    Despite their best and frequently heroic efforts, school crisis intervention teams often find themselves unprepared for the many types of tragedies they face. This timely text prompts crisis intervention team members to reevaluate their beliefs and practices and consider a new approach to dealing with school crises. The author, a longtime school…

  9. Liberia's Post-War Recovery: Key Issues and Developments

    National Research Council Canada - National Science Library

    Cook, Nicolas

    2005-01-01

    This report describes recent developments in Liberia, a small, poor West African country that is undergoing a post-conflict transition and peace-building process after its second civil war in a decade...

  10. Liability of physicans and dentists – key issues

    National Research Council Canada - National Science Library

    Michał Zalewski; Kamila Fux-Zalewska

    2016-01-01

    ... (contractual liability) or unlawful and culpable conduct in the exercise of medical action taken toward the patient who is not bound to the doctor by a legal relationship (tort liability). When a physician or a dentist is assigned a liability, he/she is obliged to redress the pecuniary damage and compensate for the non-pecuniary injury (wrong) suffered by the injured party.

  11. Danish offshore wind. Key environmental issues - a follow-up

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-02-15

    This follow-up to the Danish environmental monitoring programme on large-scale offshore wind power builds on the result of the former programme of 2006 and focuses on updated knowledge on harbour porpoises, water birds and fish communities, and on the cumulative effects of wind farms. The scientific quality of the projects in this follow-up has been assessed by experts from the International Advisory Panel of Experts on Marine Ecology (IAPEME), who have commented on the results in an independent evaluation which is reproduced in this publication. (LN)

  12. Culturally responsive integrated health care: Key issues for medical education.

    Science.gov (United States)

    Illes, Rose Anne C; Grace, Aaron J; Niño, José R; Ring, Jeffrey M

    2015-01-01

    Primary care providers are increasingly responsible for providing mental health care in the United States. For those patients who do receive specialty mental health services, the primary care provider functions as the main entry point into the mental health system. Given the persistent racial and ethnic health disparities in the United States, it is not surprising that mental health disparities also present a difficult challenge for both the U.S. health system and for frontline practitioners. Physicians-in-training require tools for rapid psychiatric assessment that will quickly identify pertinent symptom clusters and distinguish between major psychological disorders. It is incumbent on residency faculty to teach resident physicians how to provide culturally responsive mental health assessment and intervention/referral knowledge and skills toward the elimination of these disparities and toward patient-centered care. This article begins with an overview of health disparities and barriers to health and mental health care access, followed by a discussion of culturally responsive care including an example of a culturally responsive educational program in the United States that is directly targeting the problem of access in that geographic region. It concludes with a review of educational strategies for enhancing culturally responsive behavioral and mental health care by physicians in training. © The Author(s) 2015.

  13. Regional chiefs meet to discuss key issues / Ella Karapetyan

    Index Scriptorium Estoniae

    Karapetyan, Ella

    2009-01-01

    Stockholmis toimunud Põhja- ja Baltimaade peaministrite kohtumisel räägiti energiajulgeolekust, praegusest majandusolukorrast ja detsembris toimuva ÜRO kliimakonverentsi ettevalmistustest. Andrus Ansip rõhutas uue rahvusvahelise kliimalepingu tähtsust

  14. 146 Trade Unions as Organisations: Key Issues and Problems of ...

    African Journals Online (AJOL)

    User

    . It should be ... of achieving this goal http:www.the free library.com/union .... Labour Leaders used the Unions to condemn laws which they considered were not in the interest of the people. And they organized political demonstrations some of.

  15. International Food Assistance: Key Issues for Congressional Oversight

    Science.gov (United States)

    2009-09-01

    Africab Worldwide 25% more Sub-Saharan Africa 34% more Asia 29% more Latin America 2% less Source: GAO analysis of USAID and WFP data. • Nutrition...superintendents and laboratories Input suppliers (Fertilizer, seeds, tools) Large traders Intermediate traders Beneficiaries Foo d ai d Value created...world, Response to Recommendations including the Horn of Africa, Central and Southern Africa, Southeast Asia , West Africa, and the U.S. Gulf area

  16. Ethical key issues and fundamental rights in paediatric research.

    Science.gov (United States)

    Altavilla, Annagrazia

    2011-05-01

    This article is aimed at describing the methodology of "ethical reasoning" that finally led TEDDYNoE (Task-force in Europe for Drug Development for the Young) to propose the integration of international human rights law to develop coherent and exhaustive ethical recommendations on paediatric research at a European level. A large number of ethical guidelines and texts of varying legal force existing in the field of clinical research and in particular related to paediatrics are analysed. Differences and non-coordinated implementation are pointed out. Differences, tensions or outright contradictions among the provisions of these texts can generate confusion leading to the adoption of different ethical standards across Europe. In this context, the real challenge is to ensure that each child involved in a clinical trial in the EU territory may rely directly on the same principles and rights. Taking international human rights law as the main starting point to develop a coherent framework for paediatric research that incorporates all the relevant ethical considerations and existing guidelines is a way of achieving this objective. The implementation, at national and local level, of the "European Ethical Recommendations" (Eudralex 2008 vol. 10), based on international human rights law, seems to be the next step in facilitating a coordinated approach to the application of the Directive 2001/20/EC, as well as developing quality and ethically sound paediatric research.

  17. Assessment of some key issues that affect the acceptance of ...

    African Journals Online (AJOL)

    The study evaluated how technological integration affects Building Information Modelling (BIM) acceptance. Quantitative research design was used, whereby survey was employed using questionnaire as a means of data collection. A total of 190 questionnaires were distributed to the professionals in the Nigerian ...

  18. Client Centeredness and Health Reform: Key Issues for Occupational Therapy.

    Science.gov (United States)

    Mroz, Tracy M; Pitonyak, Jennifer S; Fogelberg, Donald; Leland, Natalie E

    2015-01-01

    Health reform promotes the delivery of patient-centered care. Occupational therapy's rich history of client-centered theory and practice provides an opportunity for the profession to participate in the evolving discussion about how best to provide care that is truly patient centered. However, the growing emphasis on patient-centered care also poses challenges to occupational therapy's perspectives on client-centered care. We compare the conceptualizations of client-centered and patient-centered care and describe the current state of measurement of client-centered and patient-centered care. We then discuss implications for occupational therapy's research agenda, practice, and education within the context of patient-centered care, and propose next steps for the profession. Copyright © 2015 by the American Occupational Therapy Association, Inc.

  19. Inverse Statistical Physics of Protein Sequences: A Key Issues Review.

    Science.gov (United States)

    Cocco, S; Feinauer, Christoph; Figliuzzi, Matteo; Monasson, Remi; Weigt, Martin

    2017-11-09

    In the course of evolution, proteins undergo important changes in their amino-acid sequences, while their three-dimensional folded structure and their biological function remain remarkably conserved. Thanks to modern sequencing techniques, sequence data accumulate at unprecedented pace. This provides large sets of so-called homologous, i.e.~evolutionarily related protein sequences, to which methods of inverse statistical physics can be applied. Using sequence data as the basis for the inference of Boltzmann distributions from samples of microscopic configurations or observables, it is possible to extract information about evolutionary constraints and thus protein function and structure. Here we give an overview over some biologically important questions, and how statistical-mechanics inspired modeling approaches can help to answer them. Finally, we discuss some open questions, which we expect to be addressed over the next years. © 2017 IOP Publishing Ltd.

  20. Medicaid and Managed Care: Key Data, Trends, and Issues

    Science.gov (United States)

    ... but others negotiate rates, set them by competitive bid, or combine approaches. Most states risk-adjust rates ... regarding access to care, quality, collection of encounter data, beneficiary NOTE: 36 states contract with MCOs. SOURCE: ...

  1. Public Key Cryptography.

    Science.gov (United States)

    Tapson, Frank

    1996-01-01

    Describes public key cryptography, also known as RSA, which is a system using two keys, one used to put a message into cipher and another used to decipher the message. Presents examples using small prime numbers. (MKR)

  2. Key Management Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides a secure environment to research and develop advanced electronic key management and networked key distribution technologies for the Navy and DoD....

  3. Financial Key Ratios

    OpenAIRE

    Tănase Alin-Eliodor

    2014-01-01

    This article focuses on computing techniques starting from trial balance data regarding financial key ratios. There are presented activity, liquidity, solvency and profitability financial key ratios. It is presented a computing methodology in three steps based on a trial balance.

  4. Who Needs Ten-Finger Typing?

    Science.gov (United States)

    Brady, Holly

    1984-01-01

    Issues related to the teaching of typing are discussed, focusing on the need for typing skills when using computers. Also compares use of the "QWERTY" to the Dvorak keyboards, considering the advantages and disadvantages of each. (JN)

  5. Ten themes of viscous liquid dynamics

    DEFF Research Database (Denmark)

    Dyre, J. C.

    2007-01-01

    simplifies the theory by allowing for an ultra-local Hamiltonian (free energy), but also explains the observed general independence of chemistry. Whereas there are no long-ranged static (i.e., equal-time) correlations in the model, there are important long-ranged dynamic correlations on the alpha timescale.......Ten ‘themes' of viscous liquid physics are discussed with a focus on how they point to a general description of equilibrium viscous liquid dynamics (i.e., fluctuations) at a given temperature. This description is based on standard time-dependent Ginzburg-Landau equations for the density fields...

  6. Water Sustainability Assessment for Ten Army Installations

    Science.gov (United States)

    2011-03-26

    the severity of this scarcity varies by scenario. It seems that natural condi- tions play a bigger part in water availability for the region than does...question lies with: (1) a picture of how short-term water scarcity might play out across the region, which is outside of the scope of this study, and...ER D C/ CE RL T R- 11 -5 Water Sustainability Assessment for Ten Army Installations Co ns tr uc tio n En gi ne er in g R es

  7. Ten Guidelines for Translating Legal Texts

    Directory of Open Access Journals (Sweden)

    Alenka Kocbek

    2017-12-01

    Full Text Available The paper proposes a targeted model for translating legal texts, developed by the author by combining translation science (i.e. functionalist approaches with the findings of comparative law and legal linguistics. It consists of ten guidelines directing the translator from defining the intended function of the target text and selecting the corresponding translation type, through comparing the legal systems involved in the translation and analysing the memetic structure of the source text and parallel texts in the target culture to designing the target text as a cultureme and ensuring its legal security.

  8. Supersymmetric R4-actions in ten dimensions

    OpenAIRE

    de Roo, M.; Suelmann, H.; Wiedemann, A.

    1992-01-01

    We construct supersymmetric R+R4-actions in ten dimensions. Two invariants, of which the bosonic parts are known from string amplitude and sigma model calculations, are obtained. One of these invariants can be generalized to an R+F2+F4-invariant for supersymmetric Yang-Mills theory coupled to supergravity. Supersymmetry requires the presence of B ^ R ^ R ^ R ^ R-terms, (B ^ F ^ F ^ F ^ F for Yang-Mills) which correspond to counterterms in the Green-Schwarz anomaly cancellation.

  9. Ten essential skills for electrical engineers

    CERN Document Server

    Dorr, Barry

    2014-01-01

    Engineers know that, as in any other discipline, getting a good job requires practical, up-to-date skills. An engineering degree provides a broad set of fundamentals. Ten Essential Skills applies those fundamentals to practical tasks required by employers. Written in a user-friendly, no-nonsense format, the book reviews practical skills using the latest tools and techniques, and features a companion website with interview practice problems and advanced material for readers wishing to pursue additional skills. With this book, aspiring and current engineers may approach job interviews confident

  10. The Top Ten Algorithms in Data Mining

    CERN Document Server

    Wu, Xindong

    2009-01-01

    From classification and clustering to statistical learning, association analysis, and link mining, this book covers the most important topics in data mining research. It presents the ten most influential algorithms used in the data mining community today. Each chapter provides a detailed description of the algorithm, a discussion of available software implementation, advanced topics, and exercises. With a simple data set, examples illustrate how each algorithm works and highlight the overall performance of each algorithm in a real-world application. Featuring contributions from leading researc

  11. Cloning and analysis of the HMG domains of ten Sox genes from ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-04-20

    Apr 20, 2009 ... Full Length Research Paper. Cloning and analysis of the HMG domains of ten Sox genes from Bombina maxima (Amphibia: Anura). Jingjing Wang, Ning Wang and Liu-wang Nie*. The Provincial Key Lab. of the Conservation and Exploitation Research of Biological Resources in Anhui, College of Life.

  12. TENS (transcutaneous electrical nerve stimulation) for labour pain.

    Science.gov (United States)

    Francis, Richard

    2012-05-01

    Because TENS is applied inconsistently and not always in line with optimal TENS application theory, this may explain why TENS for labour pain appears to be effective in some individuals and not in others. This article reviews TENS theory, advises upon optimal TENS application for labour pain and discusses some of the limitations of TENS research on labour pain. TENS application for labour pain may include TENS applied to either side of the lower spine, set to 200 mus pulse duration and 100 pulses per second. As pain increases, TENS intensity should be increased and as pain decreases, TENS intensity should be reduced to maintain a strong but pain free intensity of stimulation. This application may particularly reduce back pain during labour.

  13. Senegal; Selected Issues

    OpenAIRE

    International Monetary Fund

    2015-01-01

    This Selected Issues paper analyzes Senegal’s real effective exchange rate (REER) and external competitiveness. A REER significantly above its equilibrium, as determined by economic fundamentals, can impede a country’s external competitiveness, calling for corrective macroeconomic measures. This paper finds no conclusive evidence of a REER overvaluation, implying that structural reforms are key to improving Senegal’s external competitiveness. The paper also describes Senegal’s export performa...

  14. Nigeria; Selected Issues Paper

    OpenAIRE

    International Monetary Fund

    2015-01-01

    This Selected Issues paper discusses promotion of economic transformation in Nigeria. Nigeria’s long-term potential is keyed on promoting economic transformation. This implies taking stock of initial conditions, assessing long-term financing capacity, and evaluating the policies and reforms to be implemented to meet the long term vision. The recent fall in prices has highlighted the challenging but compelling need to address remaining development challenges. This paper discusses some of these...

  15. Bhutan; Selected Issues

    OpenAIRE

    International Monetary Fund

    1997-01-01

    This Selected Issues paper describes the current tax system in Bhutan and suggests options for tax policy reform. Though significant hydropower revenues are expected in the medium term as major projects come on-stream, reforms to the existing tax system in the interim will generate fiscal room and prevent recourse to domestic debt to finance development needs. Key reforms include reducing tax exemptions in the near term and introduction of value-added tax in the medium term. The paper also an...

  16. Clinical Trials: A Crucial Key to Human Health Research

    Science.gov (United States)

    Skip Navigation Bar Home Current Issue Past Issues Clinical Trials: A Crucial Key to Human Health Research Past ... the forefront of human health research today are clinical trials—studies that use human volunteers to help medical ...

  17. Assessment of hypoallergenicity of ten skincare products.

    Science.gov (United States)

    Brandt, Staci; Lio, Peter

    2014-03-01

    Sensitive skin is a common skin complaint frequently associated with skin diseases or adverse reactions to cosmetic products. Manufacturers have produced numerous products targeted for patients with sensitive skin and frequently label these products as being hypoallergenic. This term implies that the product may be less likely to cause an allergic reaction and be better suited for those with sensitive skin. However, there is no federal regulatory definition of this term and products may not have clinical support of their claim. Patch testing ingredients is frequently done to identify potential irritants; however, patch-testing product formulations may provide more realistic expectations about potential skin sensitivity and help support claims of hypoallergenicity. Ten skincare products were assessed for their sensitizing potential and hypoallergenicity in 14 repeat insult patch test clinical studies, involving over 2,000 subjects. In these studies, the products were deemed to be hypoallergenic if there was no evidence of sensitization or allergic reactions. The results from these trials demonstrated that all ten products were well tolerated, showed no sensitization or allergic reactions, and support claims of hypoallergenicity.

  18. Ten principles of good interdisciplinary team work.

    Science.gov (United States)

    Nancarrow, Susan A; Booth, Andrew; Ariss, Steven; Smith, Tony; Enderby, Pam; Roots, Alison

    2013-05-10

    Interdisciplinary team work is increasingly prevalent, supported by policies and practices that bring care closer to the patient and challenge traditional professional boundaries. To date, there has been a great deal of emphasis on the processes of team work, and in some cases, outcomes. This study draws on two sources of knowledge to identify the attributes of a good interdisciplinary team; a published systematic review of the literature on interdisciplinary team work, and the perceptions of over 253 staff from 11 community rehabilitation and intermediate care teams in the UK. These data sources were merged using qualitative content analysis to arrive at a framework that identifies characteristics and proposes ten competencies that support effective interdisciplinary team work. Ten characteristics underpinning effective interdisciplinary team work were identified: positive leadership and management attributes; communication strategies and structures; personal rewards, training and development; appropriate resources and procedures; appropriate skill mix; supportive team climate; individual characteristics that support interdisciplinary team work; clarity of vision; quality and outcomes of care; and respecting and understanding roles. We propose competency statements that an effective interdisciplinary team functioning at a high level should demonstrate.

  19. Merging clinical pathway programs as part of overall health system mergers: a ten-step guide. Spectrum Health.

    Science.gov (United States)

    Schriefer, J; Engelhard, J; DiCesare, L; Miller, M; Schriefer, J

    2000-01-01

    Mergers, acquisitions, and reorganizations can be stressful and accompanied by ambivalence, confusion, and uncertainty. Providing clear and simple steps for merging clinical pathways may help organizations move through the transition process more smoothly. The ten steps according to which Spectrum Health merged its pathway program-conduct an inventory of previous efforts, plan for the ideal program, bring staff together early in the merger process, decide on a common format, standardize the development and revision process, standardize a reporting tool, create a clinical pathway manual, implement an educational plan, present the program to key customers, and appoint an advisory group-need not be done sequentially. The ten-step pathway merger program uses pathways as a means to improve the quality of the care provided, with a focus on multidisciplinary clinical pathway teamwork. Before the merger, the two hospital systems' pathway programs used different approaches to operations and pathway format. When the announcement to merge came in September 1997, steps to merge the clinical pathway programs began. More than two years into the merger, Spectrum Health continues to struggle with the evolution of the health system. Clinical pathways represent just one of the significant and extensive issues related to organizational mergers; organizational values, finances, vision, mission, customer relations, strategic priorities, and people issues are a few of the others. Focusing on merging programs such as clinical pathway programs can help put one large piece of the merger puzzle in place and reduce some of the ambiguity associated with all mergers. Executive support is critical to the success of the clinical pathway program.

  20. LOCKS AND KEYS SERVICE

    CERN Multimedia

    Locks and Keys Service

    2002-01-01

    The Locks and Keys service (ST/FM) will move from building 55 to building 570 from the 2nd August to the 9th August 2002 included. During this period the service will be closed. Only in case of extreme urgency please call the 164550. Starting from Monday, 12th August, the Locks and Keys Service will continue to follow the activities related to office keys (keys and locks) and will provide the keys for furniture. The service is open from 8h30 to 12h00 and from 13h00 to 17h30. We remind you that your divisional correspondents can help you in the execution of the procedures. We thank you for your comprehension and we remain at your service to help you in solving all the matters related to keys for offices and furniture. Locks and Keys Service - ST Division - FM Group

  1. Key Note: Living with droughts?

    OpenAIRE

    Erdbrink, C. D.; van Beek, Eelco; van Os, A.G.

    2008-01-01

    The Netherlands Center for River Research (NCR) in its first 10 years of existence has focused its activities on flooding. Climate change might cause that droughts will become as important as or even more important than floods. The dry year 2003 in Europe has shown the huge socio-economic impacts of droughts. New concepts are emerging on how to deal with droughts. This key-note addresses the issues of droughts and scarcity and makes a plea to include more drought research in NCR.

  2. Theoretical Issues

    Energy Technology Data Exchange (ETDEWEB)

    Marc Vanderhaeghen

    2007-04-01

    The theoretical issues in the interpretation of the precision measurements of the nucleon-to-Delta transition by means of electromagnetic probes are highlighted. The results of these measurements are confronted with the state-of-the-art calculations based on chiral effective-field theories (EFT), lattice QCD, large-Nc relations, perturbative QCD, and QCD-inspired models. The link of the nucleon-to-Delta form factors to generalized parton distributions (GPDs) is also discussed.

  3. Diæten - et andet perspektiv

    DEFF Research Database (Denmark)

    Agerholm, Frank Juul

    2014-01-01

    Temaet for den seneste udgave af vores studenterblad ”Næringsstoffet” er ”Et andet perspektiv”. Ifølge redaktionens oplæg kunne det eksempelvis dreje sig om »artikler om nye kropsidealer, at sundhed ikke kun handler om, hvad man propper i munden, forskellige perspektiver på de nye kostråd, altern......, alternative kostformer (5:2 kuren) osv.«. Det gav mig anledning til et indlæg, hvor jeg har forsøgt at strejfe flere punkter fra listen med et andet perspektiv på diæten. I bloggen gengives det indlæg i en lettere tilrettet version....

  4. Electroanaesthesia--from torpedo fish to TENS.

    Science.gov (United States)

    Francis, J; Dingley, J

    2015-01-01

    In 153 AD, the Roman physician Scribonius Largus identified that electric current had analgesic properties, instructing patients to stand on an electric ray for the treatment of gout. In 2014, transcranial magnetic stimulation was approved by the National Institute for Health and Care Excellence for the treatment of migraine. Although separated by nearly two millennia, these milestones represent the evolution of the utilisation of electric current in medical and anaesthetic practice. Significant advances have been made over the last century in particular, and during the 1960s and 1970s, tens of thousands of patients were reportedly anaesthetised for surgical interventions using electric current as the anaesthetic agent. Many medical interventions, including transcutaneous electrical nerve stimulation and deep brain stimulation, have evolved in the aftermath of investigations into electroanaesthesia; the potential for electric current to be an anaesthetic agent of the future still exists. © 2014 The Association of Anaesthetists of Great Britain and Ireland.

  5. Ten Reasons Service Science Matters to Universities

    Science.gov (United States)

    Spohrer, Jim; Fodell, Dianne; Murphy, Wendy

    2012-01-01

    Higher education is being reshaped little by little every day. Slowly but surely, from the smallest community colleges to the teaching institutions to the most prestigious research universities, a new set of key performance indicators (KPIs) is transforming what excellence means in higher education. For developed and emerging market nations…

  6. Policy issues in modern cartography

    CERN Document Server

    Taylor, DRF

    1998-01-01

    Policy Issues in Modern Cartography contains the views of national mapping agencies, legal scholars, the library community, the private sector and academia on these and many other important issues. The book begins with perspectives from national mapping agencies in Britain, Canada and the United States followed by a survey of the situation in Asia. The next three chapters deal primarily with legal issues such as copyright and intellectual property from both North American and European perspectives. Chapter 8 presents an important perspective on the key issues by a representative of the privat

  7. Simultaneous determination of ten preservatives in ten kinds of foods by micellar electrokinetic chromatography.

    Science.gov (United States)

    Ding, Xiao-Jing; Xie, Na; Zhao, Shan; Wu, Yu-Chen; Li, Jiang; Wang, Zhi

    2015-08-15

    An improved micellar electrokinetic capillary chromatography method (MEKC) for the simultaneous determination of ten preservatives in ten different kinds of food samples was reported. An uncoated fused-silica capillary with 50 μm i.d. and 70 cm total length was used. Under the optimized conditions, the linear response was observed in the range of 1.2-200mg/L for the analytes. The limits of detection (LOD, S/N=3) and limits of quantitation (LOQ, S/N=10) ranging from 0.4 to 0.5mg/L and 1.2 to 1.5mg/L, respectively were obtained. The method was used for the determination of sorbic and benzoic acids in two FAPAS® (Food Analysis Performance Assessment Scheme) proficiency test samples (jam and chocolate cake). The results showed that the current method with simple sample pretreatment and small reagent consumption could meet the needs for routine analysis of the ten preservatives in ten types of food products. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Successful dexamethasone pulse therapy in a toxic epidermal necrolysis (TEN) patient featuring recurrent TEN to oxazepam

    NARCIS (Netherlands)

    van der Meer, J B; Schuttelaar, M L; Toth, G G; Kardaun, S H; Beerthuizen, G; de Jong, M C; Jonkman, M F; Nieuwenhuis, P

    2001-01-01

    A 62-year-old female patient is described who developed toxic epidermal necrolysis (TEN) after medication with phenytoin and oxazepam. Initially phenytoin was discontinued and dexamethasone pulse therapy (1.5 mg/kg on 3 consecutive days) was initiated on the tenth day of skin disease. This resulted

  9. Raccoon removal reduces sea turtle nest depredation in the Ten Thousand Islands of Florida

    Science.gov (United States)

    Garmestani, A.S.; Percival, H.F.

    2005-01-01

    Predation by raccoons, Procyon lotor marinus (L.), is the primary cause of sea turtle nest loss in the Ten Thousand Islands archipelago. Four islands within Ten Thousand Islands National Wildlife Refuge were surveyed for sea turtle nesting activity from 1991-95. Raccoons depredated 76-100% of nests on Panther Key from 1991-94, until 14 raccoons were removed in 1995 resulting in 0% depredation and 2 more were removed in 1996 resulting in 0% depredation. Raccoon removal may be an effective management option for increasing sea turtle nest survival on barrier islands.

  10. The compact key

    NARCIS (Netherlands)

    NN,

    1966-01-01

    Here is given a sample of a new sort of identification key, recently developed by Dr. P. W. Leenhouts of the Rijksherbarium. Having to sort many specimens of Sapindaceae into genera, he became dissatisfied with the common dichotomous key, which too often does not work when the material is not

  11. Radiation and other risk issues in Norwegian newspapers ten years after Chernobyl

    Energy Technology Data Exchange (ETDEWEB)

    Nilsson, Aa.; Reitan, J.B.; Toennesen, A.; Waldahl, R.

    1997-09-01

    Content analysis of risk articles has been performed in 1996 for five Norwegian newspapers four weeks before and four weeks after the 10th anniversary of the Chernobyl accident in 1986. The main focus has been on radiation and/or nuclear risks. The report is part of an international project on risk perception and communication. 94 refs.

  12. Ten years of bored tunnels in the Netherlands : Part II: Structural issues

    NARCIS (Netherlands)

    Bakker, K.J.; Bezuijen, A.

    2008-01-01

    In 1997 for the first time construction of bored tunnels in the Netherlands soft soil was undertaken. Before that date essentially only immersed tunnels and cut-and-cover tunnels were constructed in the Netherlands. The first two bored tunnels were Pilot Projects, the 2nd Heinenoord tunnel and the

  13. Romania: Ten Years of EU Membership

    Directory of Open Access Journals (Sweden)

    Gábor Hunya

    2017-06-01

    Full Text Available By joining the European Union as of 1st of January 2007, Romania made use of a window of opportunity which may not have been open later. In the ten years that followed, advantages and challenges of the membership have in part been overshadowed by the impact of the global financial crisis. The country went through a boom-bust-boom economic cycle. The swing from overheating to depression and back again to overheating has been amplified by pro-cyclical economic policy. Romania has been a selective policy taker in the EU often delaying fiscal and legal actions resulting in lost benefits. By reviewing the current political uncertainties in Europe, the conclusion emerges that more effective governance and more active foreign policy is necessary under the current Europe-wide orientation loss. The country may need to develop a mobilising strategy and policy beyond the direct benefits provided by the EU, one that also contributes to the success of the European integration.

  14. Questioning ten common assumptions about peatlands

    Directory of Open Access Journals (Sweden)

    University of Leeds Peat Club:

    2017-07-01

    Full Text Available Peatlands have been widely studied in terms of their ecohydrology, carbon dynamics, ecosystem services and palaeoenvironmental archives. However, several assumptions are frequently made about peatlands in the academic literature, practitioner reports and the popular media which are either ambiguous or in some cases incorrect. Here we discuss the following ten common assumptions about peatlands: 1. the northern peatland carbon store will shrink under a warming climate; 2. peatlands are fragile ecosystems; 3. wet peatlands have greater rates of net carbon accumulation; 4. different rules apply to tropical peatlands; 5. peat is a single soil type; 6. peatlands behave like sponges; 7. Sphagnum is the main ‘ecosystem engineer’ in peatlands; 8. a single core provides a representative palaeo-archive from a peatland; 9. water-table reconstructions from peatlands provide direct records of past climate change; and 10. restoration of peatlands results in the re-establishment of their carbon sink function. In each case we consider the evidence supporting the assumption and, where appropriate, identify its shortcomings or ways in which it may be misleading.

  15. Ten tips for authors of scientific articles.

    Science.gov (United States)

    Hong, Sung-Tae

    2014-08-01

    Writing a good quality scientific article takes experience and skill. I propose 'Ten Tips' that may help to improve the quality of manuscripts for scholarly journals. It is advisable to draft first version of manuscript and revise it repeatedly for consistency and accuracy of the writing. During the drafting and revising the following tips can be considered: 1) focus on design to have proper content, conclusion, points compliant with scope of the target journal, appropriate authors and contributors list, and relevant references from widely visible sources; 2) format the manuscript in accordance with instructions to authors of the target journal; 3) ensure consistency and logical flow of ideas and scientific facts; 4) provide scientific confidence; 5) make your story interesting for your readers; 6) write up short, simple and attractive sentences; 7) bear in mind that properly composed and reflective titles increase chances of attracting more readers; 8) do not forget that well-structured and readable abstracts improve citability of your publications; 9) when revising adhere to the rule of 'First and Last' - open your text with topic paragraph and close it with resolution paragraph; 10) use connecting words linking sentences within a paragraph by repeating relevant keywords.

  16. Choledochal cysts: our ten year experience.

    LENUS (Irish Health Repository)

    Cianci, F

    2012-04-01

    We present our experience in the management of choledochal cysts from 1999 to 2009. A retrospective review of all charts with a diagnosis of choledochal cysts in our institution in this ten-year period. Data was collated using Excel. A total of 17 patients were diagnosed with choledochal cyst: 9 females and 8 males. The average age at diagnosis was 28 months (range from 0 to 9 years). The most common presenting symptoms were obstructive jaundice 6 (35%) and abdominal pain and vomiting 4 (23%). Ultrasound (US) was the initial diagnostic test in all cases with 4 patients requiring further investigations. All patients underwent Roux-en-Y Hepaticojejunostomy. The average length of stay was 11 days. Patients were followed up with Liver Function Tests (LFTS) and US 4-6 weeks post-operatively. Three patients developed complications including post-op collection, high drain output requiring blood transfusion and adhesive bowel obstruction. Our overall experience with choledochal cyst patients has been a positive one with effective management and low complication rates.

  17. The first ten years of Swift supernovae

    Science.gov (United States)

    Brown, Peter J.; Roming, Peter W. A.; Milne, Peter A.

    2015-09-01

    The Swift Gamma Ray Burst Explorer has proven to be an incredible platform for studying the multiwavelength properties of supernova explosions. In its first ten years, Swift has observed over three hundred supernovae. The ultraviolet observations reveal a complex diversity of behavior across supernova types and classes. Even amongst the standard candle type Ia supernovae, ultraviolet observations reveal distinct groups. When the UVOT data is combined with higher redshift optical data, the relative populations of these groups appear to change with redshift. Among core-collapse supernovae, Swift discovered the shock breakout of two supernovae and the Swift data show a diversity in the cooling phase of the shock breakout of supernovae discovered from the ground and promptly followed up with Swift. Swift observations have resulted in an incredible dataset of UV and X-ray data for comparison with high-redshift supernova observations and theoretical models. Swift's supernova program has the potential to dramatically improve our understanding of stellar life and death as well as the history of our universe.

  18. Comparative Genomics of Ten Solanaceous Plastomes

    Directory of Open Access Journals (Sweden)

    Harpreet Kaur

    2014-01-01

    Full Text Available Availability of complete plastid genomes of ten solanaceous species, Atropa belladonna, Capsicum annuum, Datura stramonium, Nicotiana sylvestris, Nicotiana tabacum, Nicotiana tomentosiformis, Nicotiana undulata, Solanum bulbocastanum, Solanum lycopersicum, and Solanum tuberosum provided us with an opportunity to conduct their in silico comparative analysis in depth. The size of complete chloroplast genomes and LSC and SSC regions of three species of Solanum is comparatively smaller than that of any other species studied till date (exception: SSC region of A. belladonna. AT content of coding regions was found to be less than noncoding regions. A duplicate copy of trnH gene in C. annuum and two alternative tRNA genes for proline in D. stramonium were observed for the first time in this analysis. Further, homology search revealed the presence of rps19 pseudogene and infA genes in A. belladonna and D. stramonium, a region identical to rps19 pseudogene in C. annum and orthologues of sprA gene in another six species. Among the eighteen intron-containing genes, 3 genes have two introns and 15 genes have one intron. The longest insertion was found in accD gene in C. annuum. Phylogenetic analysis using concatenated protein coding sequences gave two clades, one for Nicotiana species and another for Solanum, Capsicum, Atropa, and Datura.

  19. Role of nanocrystalline silver dressings in the management of toxic epidermal necrolysis (TEN) and TEN/Stevens-Johnson syndrome overlap.

    Science.gov (United States)

    Smith, Saxon D; Dodds, Annabel; Dixit, Shreya; Cooper, Alan

    2015-11-01

    Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are severe mucocutaneous eruptions. There is currently no defined optimal approach to wound care. The objective of this study was to evaluate silver dressings in the wound-care management of TEN and SJS/TEN syndrome overlap with a retrospective case review of nine patients with TEN and SJS/TEN overlap presenting to our institution. Nanocrystalline silver dressings appear to be useful in the rapid commencement of healing in these patients. TEN and SJS/TEN overlap are rare conditions. This contributed to a relatively small number of cases included in the study. The ease of application, antimicrobial properties and low frequency of change make nanocrystalline silver dressings ideal in TEN/SJS. © 2014 The Australasian College of Dermatologists.

  20. "Take ten minutes": a dedicated ten minute medication review reduces polypharmacy in the elderly.

    LENUS (Irish Health Repository)

    Walsh, E K

    2010-09-01

    Multiple and inappropriate medications are often the cause for poor health status in the elderly. Medication reviews can improve prescribing. This study aimed to determine if a ten minute medication review by a general practitioner could reduce polypharmacy and inappropriate prescribing in elderly patients. A prospective, randomised study was conducted. Patients over the age of 65 (n = 50) underwent a 10-minute medication review. Inappropriate medications, dosage errors, and discrepancies between prescribed versus actual medication being consumed were recorded. A questionnaire to assess satisfaction was completed following review. The mean number of medications taken by patients was reduced (p < 0.001). A medication was stopped in 35 (70%) patients. Inappropriate medications were detected in 27 (54%) patients and reduced (p < 0.001). Dose errors were detected in 16 (32%). A high level of patient satisfaction was reported. A ten minute medication review reduces polypharmacy, improves prescribing and is associated with high levels of patient satisfaction.

  1. "Take ten minutes": a dedicated ten minute medication review reduces polypharmacy in the elderly.

    LENUS (Irish Health Repository)

    Walsh, E K

    2012-02-01

    Multiple and inappropriate medications are often the cause for poor health status in the elderly. Medication reviews can improve prescribing. This study aimed to determine if a ten minute medication review by a general practitioner could reduce polypharmacy and inappropriate prescribing in elderly patients. A prospective, randomised study was conducted. Patients over the age of 65 (n = 50) underwent a 10-minute medication review. Inappropriate medications, dosage errors, and discrepancies between prescribed versus actual medication being consumed were recorded. A questionnaire to assess satisfaction was completed following review. The mean number of medications taken by patients was reduced (p < 0.001). A medication was stopped in 35 (70%) patients. Inappropriate medications were detected in 27 (54%) patients and reduced (p < 0.001). Dose errors were detected in 16 (32%). A high level of patient satisfaction was reported. A ten minute medication review reduces polypharmacy, improves prescribing and is associated with high levels of patient satisfaction.

  2. Importance of TEN-T Corridors in the Development of Infrastructure Example of Visegrad Group Countries

    Directory of Open Access Journals (Sweden)

    Khúlová Lucia

    2016-06-01

    Full Text Available Transport is one of key factors of the development of each modern society. It is one of the most important areas that governments all around the world should address when developing national policy. The objective of the article is to define the importance of Trans-European Network - Transport (TEN-T corridors in the development of infrastructure connections between groups of countries known as Visegrad group. TEN-T core network represents a trans-European transport system and includes the priority area of transport infrastructure. Individual Member States are obliged to complete the TEN-T core on its territory not later than 31.12.2030. The Visegrad group countries as neighbourhood countries presents perspective platform for cooperation in infrastructure development.

  3. Keys to the City

    DEFF Research Database (Denmark)

    Monsson, Christian Kjær

    2014-01-01

    Review of: Keys to the City: How Economics, Institutions, Social Interaction, and Politics Shape Development / Michael Storper Princeton University Press, Princeton, NJ, 2013, 288 pp., $39.95/£27.95 (cloth), ISBN 9780691143118......Review of: Keys to the City: How Economics, Institutions, Social Interaction, and Politics Shape Development / Michael Storper Princeton University Press, Princeton, NJ, 2013, 288 pp., $39.95/£27.95 (cloth), ISBN 9780691143118...

  4. Japanese hospitals--culture and competition: a study of ten hospitals.

    Science.gov (United States)

    Anbäcken, O

    1994-01-01

    Japanese health care is characterized by a pluralistic system with a high degree of private producers. Central government regulates the prices and the financing system. All citizens are covered by a mandatory employment-based health insurance operating on a non-profit basis. The consumer has a free choice of physician and hospital. A comparison between Japan, Sweden and some other countries shows significant dissimilarities in the length of stay, number of treatments per hospital bed and year and the staffing of hospitals. About 80 per cent of the hospitals and 94 per cent of the clinics are privately owned. The typical private hospital owned by a physician has less than 100 beds. In this paper, data collected (1992/93) in an empirical study of Japanese hospitals and their leadership is presented. Also discussed are the hospitals' style of management, tools and strategies for competition and competences--personal and formal skills required of the leadership in the hospital. There follows a study of ten hospitals, among which hospital directors and chief physicians were interviewed. Interviews are also made with key persons in the Ministry of Health and Welfare and other organizations in the health care field. The result is also analysed from a cultural perspective--'what kind of impact does the Japanese culture have on the health care organization?' and/or 'what kind of sub-culture is developed in the Japanese hospitals'. Some comparisons are made with Sweden, USA, Canada and Germany. The different roles of the professions in the hospital are included in the study as well as the incentives for different kinds of strategies--specialization, growing in size, investments in new equipment, different kind of ownership and hospitals. Another issue discussed is the attempt to uncover whether there is an implicit distribution of specialties--silent agreements between hospitals, etc.

  5. The TEN-T core network and the Fehmarnbelt region

    DEFF Research Database (Denmark)

    Guasco, Clement Nicolas

    This note is a snapshot picture, taken in early 2014, that places the Green STRING corridor project within the context of the TEN-T strategy and gives a summarized overview on the impact of this strategy in the region. Chapter 1 contains a summary of the TEN-T strategy today, chapter 2 presents...... the sources used for this note, chapter 3 presents all the relevant EU regulations with direct impact on the development of TEN-T corridors, chapter 4 gives practical examples of the challenges for the development of TEN-T corridors, chapter 5 pre-sents the national initiatives related to the TEN-T corridor...

  6. Emerging critical issues and technology needs

    Energy Technology Data Exchange (ETDEWEB)

    Arvizu, D.E.; Baker, A.B.

    1997-08-01

    In April 1997, a panel of experts representing private sector electricity companies met to identify emerging critical issues in the electricity sector and to ascertain how technology can help with these issues. Sandia National laboratories sponsored and conducted the meeting. The panel determined the top eight issues that will be critically important over the next five to ten years, when the electricity sector is expected to undergo a major transition in its market and the regulations that govern it. This report presents a discussion of the selection and ranking of critical issues identified by the panel and the research priorities that were identified.

  7. Public/private key certification authority and key distribution. Draft

    Energy Technology Data Exchange (ETDEWEB)

    Long, J.P.; Christensen, M.J.; Sturtevant, A.P.; Johnston, W.E.

    1995-09-25

    Traditional encryption, which protects messages from prying eyes, has been used for many decades. The present concepts of encryption are built from that heritage. Utilization of modern software-based encryption techniques implies much more than simply converting files to an unreadable form. Ubiquitous use of computers and advances in encryption technology coupled with the use of wide-area networking completely changed the reasons for utilizing encryption technology. The technology demands a new and extensive infrastructure to support these functions. Full understanding of these functions, their utility and value, and the need for an infrastructure, takes extensive exposure to the new paradigm. This paper addresses issues surrounding the establishment and operation of a key management system (i.e., certification authority) that is essential to the successful implementation and wide-spread use of encryption.

  8. Ten-year retrospective: OPEC and the world oil market

    Energy Technology Data Exchange (ETDEWEB)

    Gately, D.

    1984-09-01

    This paper reviews the main events in the world oil market since 1973 and some major explanations as to what happened and why (Section I). Then there is a discussion of some projections for the next two decades and of some implications of various theories about OPEC's decisionmaking process (Section II). Section III summarizes what we have learned about modeling OPEC and the world oil market. This includes: the dominant theoretical approach based on the wealth-maximization model of Harold Hotelling (1931); the simulation approach most common in the applied literature, which envisages target-capacity-utilization pricing by OPEC; and the difficult problem of modeling price behavior during disruptions. Finally, Section IV discusses some important unresolved issues, both theoretical and empirical. A variety of contributions to the literature are considered, but the discussion pays special attention to two important recent works. One is the book OPEC Behavior and World Oil Prices (1982) (EAPA 9:3899) edited by James Griffin and David Teece, an important collection of papers on OPEC and world oil, prepared for a 1981 conference at the University of Houston. The other is the 1980 to 1981 world oil study by the Energy Modeling Forum of Stanford Univesity, which involved ten prominent models of the world oil market. 31 references.

  9. Ten commandments of faith-based recruitment.

    Science.gov (United States)

    Lefler, Leanne L

    2009-10-01

    Recruitment of older adults for clinical research, especially racial/ethnic minorities, is challenging at best. This article reports the author's experience and reviews current literature regarding faith-based methods to recruit older Black and White women for research. Her work and the literature review suggest 10 major recommendations for faith-based recruitment. Recommendations include: Select only faith institutions with religious leaders who actively advocate and collaborate; select key advisors or "insiders" to facilitate and customize the study; use culturally appropriate and age-sensitive recruitment and study materials; use faith institution facilities and promote access; use incentives; increase "face time"; use existing faith groups to encourage peer support; make it a social event and make it fun; provide personal benefit to participation; and customize spirituality. Involvement with faith institutions may be essential to reach groups who have been underrepresented in research. Copyright 2009, SLACK Incorporated.

  10. Tenåringsdrikking i utviklingspsykologisk perspektiv

    Directory of Open Access Journals (Sweden)

    Hilde Pape

    2009-10-01

    Full Text Available  SAMMENDRAGHvorfor er alkohol så populært blant unge mennesker? Dette viktige spørsmålet har vært gjenstand for fåempiriske studier. Forskningsbasert kunnskap om alkoholens positive sider og forsterkende egenskaper erderfor av begrenset omfang. Derimot har tallrike undersøkelser fokusert på ulike skadevirkninger som følgeav tenåringsdrikking. Resultatene av denne forskningen har bidratt til å understreke behovet for en aktivrusforebyggende innsats. Innsikt i alkoholens opplevde goder er imidlertid nødvendig for å kunne utvikleeffektive forebyggingsstrategier. På denne bakgrunn er søkelyset i artikkelen rettet mot psykososiale funksjonerved unge menneskers drikkevaner. Spørsmål knyttet til gruppepress og modell-læring vil også bli berørt.Hensikten er å formidle sentrale funn fra nyere forskning på feltet. Oppsummeringsvis tyder resultatene på atalkohol har en særlig appell til ungdom som er veltilpassede og sosialt anlagte. Samtidig ser det ut til atdrikking kan bidra til å fremme utviklingsprosessen i ungdomstida, men at det primært handler om indirekteeffekter. Hvilke implikasjoner de ulike funnene har mht. forebygging, er skissert i avslutningsdelen.Pape H. Teenage alcohol use from the perspective of psychological development.Nor J EpidemiolEWhy is alcohol so popular among young people? So far, few studies have addressed this important question.The body of scientific research on the positive and reinforcing aspects of drinking is accordingly of limitedextent. Numerous studies have focused on the harmful effects of teenage alcohol use and the findings clearlyunderscore the importance of primary prevention. Knowledge about the perceived advantages of alcohol useis needed to develop effective preventive programs, however. On this background, the article focuses onpsychosocial functions of youthful drinking. Findings from recent research regarding the link between alcoholuse and various indicators of adolescent

  11. Ten new species of Telipogon (Orchidaceae, Oncidiinae from southern Peru

    Directory of Open Access Journals (Sweden)

    Galán de Mera, Antonio

    2008-06-01

    Full Text Available Ten new species of Telipogon, T. antisuyuensis, T. austroperuvianus, T. casadevalliae, T. farfanii, T. javiercastroviejoi, T. kosnipatensis, T. marleneae, T. mesotropicalis, T. santiagocastroviejoi, and T. tupayachii are described and illustrated. These are terrestrial or epiphytes of the montane humid forests from Andean valleys of southern Peru. Diagnostic morphological characters are discussed for each species. A key is provided for the species of the genus found in southern Peru. The number of Telipogon species currently recognized for the Peruvian flora is 46.Se describen e ilustran diez especies nuevas de Telipogon –T. antisuyuensis, T. austroperuvianus, T. casadevalliae, T. farfanii, T. javiercastroviejoi, T. kosnipatensis, T. marleneae, T. mesotropicalis, T. santiagocastroviejoi y T. tupayachii. Éstas son plantas terrestres o epífitas de los bosques húmedos montanos de los valles andinos del sur de Perú. Se discuten sus caracteres morfológicos diagnósticos y se propone una clave dicotómica para diferenciar las especies que crecen en el sur del país. El número de especies de Telipogon actualmente reconocidas para la flora peruana es de 46.

  12. This Issue

    Directory of Open Access Journals (Sweden)

    Editors / Herausgeber

    2015-12-01

    Full Text Available Whereas the last issue of DIEGESIS (4.1 was dedicated to “Narrative and Lies”, the current volume’s focus shifts to “Narrative and Truth”. Is there a correlation between a narrative’s truth claim and its form? Does the form of narrative allow for the possibility of certain types of truth-oriented discourses in the first place? Or does it, on the contrary, prove an impediment to authentic truthful speech?Johannes Stephan distinguishes two kinds of travelogues: those reproducing received knowledge and those attempting to present the traveller’s experiences. One example of the latter type is the Arabic ‘Travel Book’ (1764 by the Syrian author Ḥanna Dyāb, in which focalization is used not only to witness but also to visualise the experiences of the traveller.Evelyn Chew and Alex Mitchell discuss a similar problem with application to contemporary texts. They investigate the construction of truth claims in three interactive nonfiction life stories in different genres. In the three case studies, of an autobiography, a biographical docugame and a video-based web documentary respectively, subjective and objective legitimation strategies are investigated.Against a backdrop of philosophical discussions of the epistemic value of narration and with specific reference to Aristotle’s Poetics, Malte Dreyer distinguishes three forms of generating coherence in narrative texts: the causal, the teleological and the holistic. He goes on to apply these concepts to social contract theories and to discuss the validity claims of the different types of narrative explanation.In this issue’s “My Narratology” section, James Phelan responds to our questions about his personal ideas of narratology. He describes his own approach as “theorypractice” and argues in favour of conceptualising narrative as “rhetorical action”.We wish you an interesting read!

  13. Transcutaneous electrical nerve stimulation (TENS) for pain management in labour

    Science.gov (United States)

    Dowswell, Therese; Bedwell, Carol; Lavender, Tina; Neilson, James P

    2014-01-01

    Background Transcutaneous nerve stimulation (TENS) has been proposed as a means of reducing pain in labour. The TENS unit emits low-voltage electrical impulses which vary in frequency and intensity. During labour, TENS electrodes are generally placed on the lower back, although TENS may be used to stimulate acupuncture points or other parts of the body. The physiological mechanisms whereby TENS relieves pain are uncertain. TENS machines are frequently operated by women, which may increase a sense of control in labour. Objectives To assess the effects of TENS on pain in labour. Search methods We searched the Cochrane Pregnancy and Childbirth Group’s Trials Register (30 April 2011) and reference lists of retrieved papers. Selection criteria Randomised controlled trials comparing women receiving TENS for pain management in labour versus routine care, alternative non-pharmacological methods of pain relief, or placebo devices. We included all types of TENS machines. Data collection and analysis Two review authors assessed for inclusion all trials identified by the search strategy, carried out data extraction and assessed risk of bias. We have recorded reasons for excluding studies. Main results Seventeen trials with 1466 women contribute data to the review. Thirteen examined TENS applied to the back, two to acupuncture points, and two to the cranium. Overall, there was little difference in pain ratings between TENS and control groups, although women receiving TENS to acupuncture points were less likely to report severe pain (average risk ratio 0.41, 95% confidence interval 0.31 to 0.54; measured in two studies). The majority of women using TENS said they would be willing to use it again in a future labour. Where TENS was used as an adjunct to epidural analgesia there was no evidence that it reduced pain. There was no consistent evidence that TENS had any impact on interventions and outcomes in labour. There was little information on outcomes for mothers and babies. No

  14. Crystallization: Key thermodynamic, kinetic and hydrodynamic aspects

    Indian Academy of Sciences (India)

    the knowledge gaps therein that pose challenges to research as well as industrial requirements. The section is organized as follows: first, crystallization practice in industry is briefly reviewed and key issues are .... by which these clusters form is either not very well understood or scantly available in the lit- erature. Primary ...

  15. Keys through ARQ

    CERN Document Server

    Latif, Mohamed Abdel; Gamal, Hesham El

    2009-01-01

    This paper develops a novel framework for sharing secret keys using the well-known Automatic Repeat reQuest (ARQ) protocol. The proposed key sharing protocol does not assume any prior knowledge about the channel state information (CSI), but, harnesses the available opportunistic secrecy gains using only the one bit feedback, in the form of ACK/NACK. The distribution of key bits among multiple ARQ epochs, in our approach, allows for mitigating the secrecy outage phenomenon observed in earlier works. We characterize the information theoretic limits of the proposed scheme, under different assumptions on the channel spatial and temporal correlation function, and develop low complexity explicit implementations. Our analysis reveals a novel role of "dumb antennas" in overcoming the negative impact of spatial correlation, between the legitimate and eavesdropper channels, on the achievable secrecy rates. We further develop an adaptive rate allocation policy which achieves higher secrecy rates by exploiting the channe...

  16. Key World Energy Statistics

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    The IEA produced its first handy, pocket-sized summary of key energy data in 1997. This new edition responds to the enormously positive reaction to the book since then. Key World Energy Statistics produced by the IEA contains timely, clearly-presented data on supply, transformation and consumption of all major energy sources. The interested businessman, journalist or student will have at his or her fingertips the annual Canadian production of coal, the electricity consumption in Thailand, the price of diesel oil in Spain and thousands of other useful energy facts. It exists in different formats to suit our readers' requirements.

  17. Instrumentation issues in implementation science.

    Science.gov (United States)

    Martinez, Ruben G; Lewis, Cara C; Weiner, Bryan J

    2014-09-04

    Like many new fields, implementation science has become vulnerable to instrumentation issues that potentially threaten the strength of the developing knowledge base. For instance, many implementation studies report findings based on instruments that do not have established psychometric properties. This article aims to review six pressing instrumentation issues, discuss the impact of these issues on the field, and provide practical recommendations. This debate centers on the impact of the following instrumentation issues: use of frameworks, theories, and models; role of psychometric properties; use of 'home-grown' and adapted instruments; choosing the most appropriate evaluation method and approach; practicality; and need for decision-making tools. Practical recommendations include: use of consensus definitions for key implementation constructs; reporting standards (e.g., regarding psychometrics, instrument adaptation); when to use multiple forms of observation and mixed methods; and accessing instrument repositories and decision aid tools. This debate provides an overview of six key instrumentation issues and offers several courses of action to limit the impact of these issues on the field. With careful attention to these issues, the field of implementation science can potentially move forward at the rapid pace that is respectfully demanded by community stakeholders.

  18. Special issue on Computational Neuroscience - PREFACE

    DEFF Research Database (Denmark)

    Ditlevsen, Susanne; Lansky, Petr

    2014-01-01

    This Special Issue of Mathematical Biosciences and Engineering contains ten selected papers presented at the Neural Coding 2012 workshop. Neuroscience is traditionally very close to mathematics which stems from the famous theoretical work of McCulloch--Pitts and Hodgkin--Huxley in the middle...

  19. Ten years of the new Russia

    Directory of Open Access Journals (Sweden)

    Francesc Serra Massansalvador

    2002-10-01

    Full Text Available This article analyzes developments in Russia since the breaking-up of the Soviet Union in 1991. Given this objective, the author places particular emphasis on the debate on social and identity issues raised by the political and ideological transition from a USSRconsidered a superpower to a country that aspire to achieving political and economic stability and, ultimately, to retaining a limited area of influence as a regional power. In this, Russia has received strong, unconditional international support, which has allowed it to overcome various obstacles, but the difficult transition that the country has been through has made it impossible to avoid a severe collective trauma in terms of ideology and identity. The process has clearly been also accompanied by a significant disregard for the individual and collective rights of the Russian people, a price that, in the long term, may be too high a one to pay for a population that aspires to stability and for a countrythat aspires to respect and to equality with the rest of the world.

  20. Ovarian Kaleidoscope database: ten years and beyond.

    Science.gov (United States)

    Hsueh, Aaron J; Rauch, Rami

    2012-06-01

    Ovarian Kaleidoscope database (OKdb) is an online, searchable, public database containing text-based and DNA microarray data to facilitate research by ovarian researchers. Using key words and predetermined categories, users can search ovarian gene information based on gene function, cell type of expression, cellular localization, hormonal regulation, mutant phenotypes, chromosomal location, ligand-receptor relationship, and other criteria, either alone or in combination. For individual genes, users can access more than 10 extensive DNA microarray datasets to interrogate gene expression patterns in a development-specific and cell type-specific manner. All ligand and receptor genes expressed in the ovary are matched to facilitate investigation of paracrine/autocrine signaling. More than 3500 ovarian genes in the database are matched to 185 gene pathways in the Kyoto Encyclopedia of Genes and Genomes to allow for elucidation of gene interactions and relationships. In addition to >400 genes with infertility or subfertility phenotypes when mutated in mice or humans, the OKdb also lists ~50 and ~40 genes associated with polycystic ovarian syndrome and primary ovarian insufficiency, respectively. The expanding OKdb is updated weekly and allows submission of new genes by ovarian researchers to allow instant access to DNA microarray datasets for newly submitted genes. The present database is a virtual community for ovarian researchers and allows users to instantaneously provide their comments for individual gene pages based on an automated Web-discussion system. In the coming years, we will continue to add new features to serve the ovarian research community.

  1. Keyed shear joints

    DEFF Research Database (Denmark)

    Hansen, Klaus

    This report gives a summary of the present information on the behaviour of vertical keyed shear joints in large panel structures. An attemp is made to outline the implications which this information might have on the analysis and design of a complete wall. The publications also gives a short...

  2. Cryptographic Key Management System

    Energy Technology Data Exchange (ETDEWEB)

    No, author

    2014-02-21

    This report summarizes the outcome of U.S. Department of Energy (DOE) contract DE-OE0000543, requesting the design of a Cryptographic Key Management System (CKMS) for the secure management of cryptographic keys for the energy sector infrastructure. Prime contractor Sypris Electronics, in collaboration with Oak Ridge National Laboratories (ORNL), Electric Power Research Institute (EPRI), Valicore Technologies, and Purdue University's Center for Education and Research in Information Assurance and Security (CERIAS) and Smart Meter Integration Laboratory (SMIL), has designed, developed and evaluated the CKMS solution. We provide an overview of the project in Section 3, review the core contributions of all contractors in Section 4, and discuss bene ts to the DOE in Section 5. In Section 6 we describe the technical construction of the CKMS solution, and review its key contributions in Section 6.9. Section 7 describes the evaluation and demonstration of the CKMS solution in different environments. We summarize the key project objectives in Section 8, list publications resulting from the project in Section 9, and conclude with a discussion on commercialization in Section 10 and future work in Section 11.

  3. Locks and Keys Service

    CERN Multimedia

    Claude Ducastel

    The GS-LS-SEM section is pleased to inform you that as from Monday 30 November 2009, the opening hours of the Locks and Keys service will be the following: 08h30 - 12h30 / 13h30 - 16:30, Mondays to Fridays. GS-SEM-LS 73333

  4. Key performance indicators

    NARCIS (Netherlands)

    Zwetsloot, G.I.J.M.

    2014-01-01

    This paper addresses how organisations can use OSH performance indicators. This is an important way to mainstream OSH into business management. Key performance indicators (KPIs) should provide objective data on the OSH situation. It is often said that ‘what gets measured gets managed’. Without

  5. Going Global: Key Insights from Two Mexican Companies

    Directory of Open Access Journals (Sweden)

    Martha RIVERA

    2015-12-01

    Full Text Available This paper explores how Mexican companies in different industries have achieved international expansion, while at the same time preserving local elements in executing their strategies. For this initial stage of research, the analysis focuses on two companies: a Grupo Bimbo, the number one company in the bakery industry worldwide and b KidZania, one of the world’s top indoor family entertainment centers. The research methodology is based on in-depth interviews with CEOs and key executives from the two companies done over a period of more than ten years. We have also used secondary data such as press releases and case studies. By contrasting their strategies and comparing them with those of other multinationals like Ford Motor Company and Santander Bank, we identified major issues that we condensed into 10 key insights. Understanding how these companies have struggled and succeeded in gaining international markets can help other companies tailor their own strategies. Our argument is that the typical simplified international expansion process is insufficient when companies need to compete in the global arena. Becoming an MNC implies handling an entire ecosystem: building local presence, establishing joint ventures or alliances with local companies, recruiting local talent, developing new business models, reshaping the value proposition, developing new brands or introducing traditional ones with a local flavor, and understanding the supply chain and routes to market. Therefore, a number of aspects have to be taken into consideration beyond just simply selecting a market. For certain companies in emerging markets, making the decision to grow internationally was not initially in their strategic vision, but economic liberalization in their home country and the threat of being purchased by an MNC from a developed country triggered the decision. There is a learning process in international expansion, and trial and error is common and useful. The

  6. Key performance indicators in hospital based on balanced scorecard model

    Directory of Open Access Journals (Sweden)

    Hamed Rahimi

    2017-01-01

    Full Text Available Introduction: Performance measurement is receiving increasing verification all over the world. Nowadays in a lot of organizations, irrespective of their type or size, performance evaluation is the main concern and a key issue for top administrators. The purpose of this study is to organize suitable key performance indicators (KPIs for hospitals’ performance evaluation based on the balanced scorecard (BSC. Method: This is a mixed method study. In order to identify the hospital’s performance indicators (HPI, first related literature was reviewed and then the experts’ panel and Delphi method were used. In this study, two rounds were needed for the desired level of consensus. The experts rated the importance of the indicators, on a five-point Likert scale. In the consensus calculation, the consensus percentage was calculated by classifying the values 1-3 as not important (0 and 4-5 to (1 as important. Simple additive weighting technique was used to rank the indicators and select hospital’s KPIs. The data were analyzed by Excel 2010 software. Results: About 218 indicators were obtained from a review of selected literature. Through internal expert panel, 77 indicators were selected. Finally, 22 were selected for KPIs of hospitals. Ten indicators were selected in internal process perspective and 5, 4, and 3 indicators in finance, learning and growth, and customer, respectively. Conclusion: This model can be a useful tool for evaluating and comparing the performance of hospitals. However, this model is flexible and can be adjusted according to differences in the target hospitals. This study can be beneficial for hospital administrators and it can help them to change their perspective about performance evaluation.

  7. Increasing intensity of TENS prevents analgesic tolerance in rats

    Science.gov (United States)

    Sato, Karina L.; Sanada, Luciana S.; Rakel, Barbara A.; Sluka, Kathleen A.

    2012-01-01

    Transcutaneous electrical nerve stimulation (TENS) reduces hyperalgesia and pain. Both low frequency (LF) and high frequency (HF) TENS, delivered at the same intensity (90% motor threshold (MT)) daily, result in analgesic tolerance with repeated use by the 5th day of treatment. Thecurrentstudytestedif 1) increasingintensityby 10% per daypreventsthedevelopmentoftolerance to repeated TENS, and 2) iflowerintensity TENS (50 % MT) produces an equivalentreduction in hyperalgesia when compared to 90% MT TENS. Sprague-Dawley rats with unilateral knee joint inflammation (3% carrageenan) were separated according to the intensity of TENS used: Sham, 50% LF, 50% HF, 90% LF, 90% HF, and increased intensity by 10% per day (LF and HF). The reduced mechanical withdrawal threshold following the induction of inflammation was reversed by application of TENS applied at 90% MT and increasing intensity for the first 4 days. On the 5th day, the groups that received 90% MT intensity showed tolerance. Nevertheless, the group that received an increased intensity on each day still showed a reversal of the mechanical withdrawal threshold with TENS. These results show that the development of tolerance can be delayed by increasing intensity of TENS. PMID:22858165

  8. Self and followers' assessment of four key leadership areas: an ...

    African Journals Online (AJOL)

    Journal of Business and Administrative Studies ... performance of a leader of a public training and consultancy institute using instruments that measure four key areas of leadership, namely, ten leadership qualities, type of power used by the leader, his role in establishing and leading teams and his emotional intelligence.

  9. Enhancing historical reasoning: a key topic in Dutch history education

    NARCIS (Netherlands)

    van Boxtel, C.; van Drie, J.

    2009-01-01

    The number of Dutch studies on the learning and teaching of history has increased substantially in the last ten years. Enhancing historical reasoning is a key topic in Dutch research on history education. This paper discusses recent and current empirical studies in the Netherlands on methods to

  10. Key Competences in Europe: Interpretation, Policy Formulation and Implementation

    Science.gov (United States)

    Halasz, Gabor; Michel, Alain

    2011-01-01

    The evolution in Europe towards more competence-based curricula in the last ten years or so is the result of several exogenous factors and a determined European policy. The Reference Framework of Key Competences for Lifelong Learning, a Recommendation approved by the European Parliament and the Council in 2006, and the work carried out within the…

  11. Transcutaneous electrical nerve stimulation (TENS) for phantom pain and stump pain following amputation in adults.

    Science.gov (United States)

    Johnson, Mark I; Mulvey, Matthew R; Bagnall, Anne-Marie

    2015-08-18

    This is the first update of a Cochrane review published in Issue 5, 2010 on transcutaneous electrical nerve stimulation (TENS) for phantom pain and stump pain following amputation in adults. Pain may present in a body part that has been amputated (phantom pain) or at the site of amputation (stump pain), or both. Phantom pain and stump pain are complex and multidimensional and the underlying pathophysiology remains unclear. The condition remains a severe burden for those who are affected by it. The mainstay treatments are predominately pharmacological, with increasing acknowledgement of the need for non-drug interventions. TENS has been recommended as a treatment option but there has been no systematic review of available evidence. Hence, the effectiveness of TENS for phantom pain and stump pain is currently unknown. To assess the analgesic effectiveness of TENS for the treatment of phantom pain and stump pain following amputation in adults. For the original version of the review we searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, PsycINFO, AMED, CINAHL, PEDRO and SPORTDiscus (February 2010). For this update, we searched the same databases for relevant randomised controlled trials (RCTs) from 2010 to 25 March 2015. We only included RCTs investigating the use of TENS for the management of phantom pain and stump pain following an amputation in adults. Two review authors independently assessed trial quality and extracted data. We planned that where available and appropriate, data from outcome measures were to be pooled and presented as an overall estimate of the effectiveness of TENS. In the original review there were no RCTs that examined the effectiveness of TENS for the treatment of phantom pain and stump pain in adults. For this update, we did not identify any additional RCTs for inclusion. There were no RCTs to judge the effectiveness of TENS for the management of phantom pain and stump pain. The published literature on TENS

  12. Physician Appraisals: Key Challenges

    Directory of Open Access Journals (Sweden)

    Klich Jacek

    2017-06-01

    Full Text Available The main purpose of the article is to identify key criteria being used for physician appraisals and to find how communication skills of physicians are valued in those appraisals. ScienceDirect and EBSCOhost databases were used for this search. The results show that a physician appraisal is underestimated both theoretically and empirically. The particular gap exists with respect to the communication skills of physicians, which are rarely present in medical training syllabi and physician assessments. The article contributes to the theoretical discourse on physician appraisals and points out at the inconsistency between the high status of physicians as a key hospital resource on the one hand and, on the other hand, at inadequate and poorly researched assessment of their performance with a special emphasis on communication skills. The article may inspire health managers to develop and implement up-to-date assessment forms for physicians and good managerial practices in this respect in hospitals and other health care units.

  13. Ancel Keys: a tribute

    Directory of Open Access Journals (Sweden)

    VanItallie Theodore B

    2005-02-01

    Full Text Available Abstract Ancel Keys, Ph.D., who died in November, 2004, at the age of 100, was among the first scientists to recognize that human atherosclerosis is not an inevitable consequence of aging, and that a high-fat diet can be a major risk factor for coronary heart disease. During World War II, he and a group of talented co-workers at the University of Minnesota conducted a large-scale study of experimentally-induced human starvation. The data generated by this study – which was immediately recognized to be a classic – continue to be of inestimable value to nutrition scientists. In his later years, Keys spent more time at his home in Naples, Italy, where he had the opportunity to continue his personal study of the beneficial effects on health and longevity of a Mediterranean diet.

  14. Authentication and key distribution for wired and wireless systems

    OpenAIRE

    Komninos, N.; Samarakoon, M. I.; Honary, B.

    2000-01-01

    With the emergence of E-Commerce communication security has become a very important issue. Two main considerations of secure communication systems are authentication, and key distribution. Authentication and key distribution may differ from one system to another due to the system parameters such as bandwidth, and available processing power at the end terminals. This paper focuses on end-to-end authentication and key management strategies in wireless and wired systems. Public and secret key en...

  15. Chapter 06: Identification key

    Science.gov (United States)

    Alex Wiedenhoeft

    2011-01-01

    The key is written to guide you through the identification process in the most efficient and accurate way possible. It presents you with a numbered series of questions and asks you to answer them. The answers you provide will be based on your interpretations of the anatomical characters in your unknown specimen and will lead you to a new set of questions. Each time you...

  16. 'Read ten thousand books, walk ten thousand miles': geographical mobility and capital accumulation among Chinese scholars

    NARCIS (Netherlands)

    Leung, M.W.H.|info:eu-repo/dai/nl/28131263X

    2013-01-01

    International movements of scientists and researchers have become more common in the increasingly inter-connected global knowledge economy. Geographic mobility is often perceived as a key to academic excellence and career advancement by scholars, especially in advanced economies. In China, where

  17. Screening Of Ten Indian Medicinal Plants For Their Antibacterial ...

    African Journals Online (AJOL)

    Screening Of Ten Indian Medicinal Plants For Their Antibacterial Activity Against Shigella sSpecies And Escherichia coli. J Thomas, B Veda. Abstract. Ethanol and Aqueous extracts of ten Indian medicinal plants were tested for their antibacterial properties against Shigella sonei, S. boydi, S. flexeneri, S. dysenteriae and ...

  18. Travels in Tartary : Decoding Ten Export Winter Landscapes

    NARCIS (Netherlands)

    Poel, van der R.H.M.

    2013-01-01

    The Chinese export paintings collection of the National Museum of Ethnology in Leiden includes ten winter views in Tartary painted on canvas. That these ten paintings have never before been studied as a group has inspired the present author to conduct research into their origins, the findings of

  19. Benchmark Dose Software Development and Maintenance Ten Berge Cxt Models

    Science.gov (United States)

    This report is intended to provide an overview of beta version 1.0 of the implementation of a concentration-time (CxT) model originally programmed and provided by Wil ten Berge (referred to hereafter as the ten Berge model). The recoding and development described here represent ...

  20. Transcutaneous electrical nerve stimulation (TENS) for neuropathic pain in adults.

    Science.gov (United States)

    Gibson, William; Wand, Benedict M; O'Connell, Neil E

    2017-09-14

    Neuropathic pain, which is due to nerve disease or damage, represents a significant burden on people and society. It can be particularly unpleasant and achieving adequate symptom control can be difficult. Non-pharmacological methods of treatment are often employed by people with neuropathic pain and may include transcutaneous electrical nerve stimulation (TENS). This review supersedes one Cochrane Review 'Transcutaneous electrical nerve stimulation (TENS) for chronic pain' (Nnoaham 2014) and one withdrawn protocol 'Transcutaneous electrical nerve stimulation (TENS) for neuropathic pain in adults' (Claydon 2014). This review replaces the original protocol for neuropathic pain that was withdrawn. To determine the analgesic effectiveness of TENS versus placebo (sham) TENS, TENS versus usual care, TENS versus no treatment and TENS in addition to usual care versus usual care alone in the management of neuropathic pain in adults. We searched CENTRAL, MEDLINE, Embase, PsycINFO, AMED, CINAHL, Web of Science, PEDro, LILACS (up to September 2016) and various clinical trials registries. We also searched bibliographies of included studies for further relevant studies. We included randomised controlled trials where TENS was evaluated in the treatment of central or peripheral neuropathic pain. We included studies if they investigated the following: TENS versus placebo (sham) TENS, TENS versus usual care, TENS versus no treatment and TENS in addition to usual care versus usual care alone in the management of neuropathic pain in adults. Two review authors independently screened all database search results and identified papers requiring full-text assessment. Subsequently, two review authors independently applied inclusion/exclusion criteria to these studies. The same review authors then independently extracted data, assessed for risk of bias using the Cochrane standard tool and rated the quality of evidence using GRADE. We included 15 studies with 724 participants. We found a

  1. TRANSCUTANEOUS ELECTRICAL NERVE-STIMULATION (TENS) IN RAYNAUDS-PHENOMENON

    NARCIS (Netherlands)

    MULDER, P; DOMPELING, EC; VANSLOCHTERENVANDERBOOR, JC; KUIPERS, WD; SMIT, AJ

    Transcutaneous nerve stimulation (TENS) has been described as resulting in vasodilatation. The effect of 2 Hz TENS of the right hand during forty-five minutes on skin temperature and plethysmography of the third digit of both hands and feet and on transcutaneous oxygen tension (TcpO2) of the right

  2. Using TENS for pain control: the state of the evidence

    Science.gov (United States)

    Vance, Carol GT; Dailey, Dana L; Rakel, Barbara A; Sluka, Kathleen A

    2014-01-01

    Summary Transcutaneous electrical nerve stimulation (TENS) is a nonpharmacological intervention that activates a complex neuronal network to reduce pain by activating descending inhibitory systems in the central nervous system to reduce hyperalgesia. The evidence for TENS efficacy is conflicting and requires not only description but also critique. Population-specific systemic reviews and meta-analyses are emerging, indicating both HF and LF TENS being shown to provide analgesia, specifically when applied at a strong, nonpainful intensity. The purpose of this article is to provide a critical review of the latest basic science and clinical evidence for TENS. Additional research is necessary to determine if TENS has effects specific to mechanical stimuli and/or beyond reduction of pain and will improve activity levels, function and quality of life. PMID:24953072

  3. Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults.

    Science.gov (United States)

    Johnson, Mark I; Claydon, Leica S; Herbison, G Peter; Jones, Gareth; Paley, Carole A

    2017-10-09

    Fibromyalgia is characterised by persistent, widespread pain; sleep problems; and fatigue. Transcutaneous electrical nerve stimulation (TENS) is the delivery of pulsed electrical currents across the intact surface of the skin to stimulate peripheral nerves and is used extensively to manage painful conditions. TENS is inexpensive, safe, and can be self-administered. TENS reduces pain during movement in some people so it may be a useful adjunct to assist participation in exercise and activities of daily living. To date, there has been only one systematic review in 2012 which included TENS, amongst other treatments, for fibromyalgia, and the authors concluded that TENS was not effective. To assess the analgesic efficacy and adverse events of TENS alone or added to usual care (including exercise) compared with placebo (sham) TENS; no treatment; exercise alone; or other treatment including medication, electroacupuncture, warmth therapy, or hydrotherapy for fibromyalgia in adults. We searched the following electronic databases up to 18 January 2017: CENTRAL (CRSO); MEDLINE (Ovid); Embase (Ovid); CINAHL (EBSCO); PsycINFO (Ovid); LILACS; PEDRO; Web of Science (ISI); AMED (Ovid); and SPORTDiscus (EBSCO). We also searched three trial registries. There were no language restrictions. We included randomised controlled trials (RCTs) or quasi-randomised trials of TENS treatment for pain associated with fibromyalgia in adults. We included cross-over and parallel-group trial designs. We included studies that evaluated TENS administered using non-invasive techniques at intensities that produced perceptible TENS sensations during stimulation at either the site of pain or over nerve bundles proximal (or near) to the site of pain. We included TENS administered as a sole treatment or TENS in combination with other treatments, and TENS given as a single treatment or as a course of treatments. Two review authors independently determined study eligibility by assessing each record and

  4. Effect of burst TENS and conventional TENS combined with cryotherapy on pressure pain threshold: randomised, controlled, clinical trial.

    Science.gov (United States)

    Macedo, L B; Josué, A M; Maia, P H B; Câmara, A E; Brasileiro, J S

    2015-06-01

    To assess the immediate effect of conventional and burst transcutaneous electrical nerve stimulation (TENS) in combination with cryotherapy on pain threshold and tolerance in healthy individuals. Randomised, controlled trial. University laboratory. One hundred and twelve healthy women. Volunteers were allocated at random to seven groups (n=16): (1) control, (2) placebo TENS, (3) conventional TENS, (4) burst TENS, (5) cryotherapy, (6) cryotherapy in combination with burst TENS, and (7) cryotherapy in combination with conventional TENS. Pain threshold and tolerance were measured by applying a pressure algometer at the lateral epicondyle of the humerus, before and after each intervention. The primary outcome measure was pressure pain threshold. A significant increase in pain threshold and tolerance at the 5% level of significance was recorded as follows: burst TENS {pain threshold: mean difference 1.3 [95% confidence interval (CI) 1.4 to 1.2]; pain tolerance: mean difference 3.8 (95% CI 3.9 to 3.7)}, cryotherapy [pain threshold: mean difference 1.3 (95% CI 1.4 to 1.2); pain tolerance: mean difference 1.9 (95% CI 1.8 to 2.0)] and cryotherapy in combination with burst TENS [pain threshold: mean difference 2.6 (95% CI 2.4 to 2.8); pain tolerance: mean difference 4.9 (95% CI 5.0 to 4.8)]. Cryotherapy in combination with burst TENS provided greater analgesia compared with the other groups (Pcryotherapy in combination with burst TENS to reduce induced pain, and suggest a potentiating effect when these techniques are combined. No such association was found between cryotherapy and conventional TENS. Copyright © 2014 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.

  5. Public key infrastructure building trusted applications and web services

    CERN Document Server

    Vacca, John R

    2004-01-01

    OVERVIEW OF PKI TECHNOLOGYPublic Key Infrastructures (PKIs): What Are They?Type of Certificate Authorities (CAS) ServicesPKI StandardsTypes of Vendor and Third-Party CA SystemsProtecting Private KeysCA System AttacksStolen Private Keys: What Can Be Done?Certificate Practice StatementsPKI ReadinessANALYZING AND DESIGNING PUBLIC KEY INFRASTRUCTURESPKI Design IssuesCost Justification and ConsiderationPKI Standards Design IssuesPKI Architectural Design ConsiderationsIMPLEMENTING PKIRequirementsImplementation ScheduleImplementation CostsPKI PerformanceMANAGING PKIRequesting a CertificateObtaining a

  6. EPa`s program for risk assessment guidelines: Exposure issues

    Energy Technology Data Exchange (ETDEWEB)

    Callahan, M.A. [Environmental Protection Agency, Washington, DC (United States)

    1990-12-31

    Three major issues to be dealt with over the next ten years in the exposure assessment field are: consistency in terminology, the impact of computer technology on the choice of data and modeling, and conceptual issues such as the use of time-weighted averages.

  7. The management of radioactive waste. A description of ten countries

    Energy Technology Data Exchange (ETDEWEB)

    Lidskog, Rolf; Andersson, Ann-Catrin [Oerebro Univ. (Sweden). Man-Technology-Environment Research Centre

    2002-07-01

    The aim of this report is to provide a description of how the responsible authorities/companies in ten EDRAM countries (International Association for Environmentally Safe Disposal of Radioactive Materials) deal with the management of radioactive waste. The focus is on how the responsible organisation currently handles this issue, including technical, economic and socio-political aspects. The material used was primarily produced by the companies/authorities themselves. The report describes the development and situation in each country up to the end of 2001, or later if noted as such in the country report. The scope of this report does not permit an evaluation of how successful and effective the companies and authorities have been in implementing their plans and ambitions. The report does not include the views of other national stakeholders concerning radwaste management, or their opinions of the way that the authorities/companies handle the issue of radwaste. The description is based on a series of questions that were drawn up and discussed at the initial stage of the EDRAM co-operation. Technological aspects: 1. What technology is used? How is research and development promoted and executed? 2. Where is the waste to be put? What criteria does each country search for? 3. How is security to be maintained? Who can obtain a license for handling nuclear waste? Economic aspects: 1. In what way do the countries in question discuss the time aspects as regards delays and similar? 2. How are the economic and financial aspects of the process dealt with? Where does the money come from? Socio-political aspects: 4. What role do politicians play and to what extent is social acceptance a part of the process? What part does public opinion play? 5. How flexible is the decision-making process and can decisions be revised? 6. Does the public have confidence in the industry and the decision-makers? 7. What kind of institutional problems arise? With regard to public involvement in

  8. Reproductive issues in anorexia nervosa

    Science.gov (United States)

    Hoffman, Elizabeth R; Zerwas, Stephanie C; Bulik, Cynthia M

    2011-01-01

    Despite a high prevalence of menstrual irregularities, women with anorexia nervosa are becoming pregnant. The physical and psychological demands of pregnancy and motherhood can represent an immense challenge for women already struggling with the medical and psychological stress of an eating disorder. This article summarizes key issues related to reproduction in women with anorexia nervosa, highlighting the importance of preconception counseling, adequate gestational weight gain, and sufficient pre- and post-natal nutrition. Postpartum issues including eating disorder symptom relapse, weight loss, breastfeeding, and risk of perinatal depression and anxiety are also discussed. PMID:22003362

  9. Hiring and Retention: Key Factors in Increasing Gender Diversity in the Geosciences

    Science.gov (United States)

    Holmes, M.; O'Connell, S.; Frey, C.

    2004-12-01

    Graduation and hiring data of geoscientists over the last ten years indicate that the largest leak in the academic pipeline for women geoscientists is at hiring into tenure-track positions. Anecdotal explanations for this leak generally cite a lack of females in the applicant pool, but women in tenure-track positions anecdotally cite a lack of family-friendly practices by academic departments. Both ideas are currently being tested via surveys of geoscience departments. Is there a way to attract more women to the field to increase the applicant pool? Results of focus groups of geoscientists indicate that both men and women are attracted into the field of geosciences by the same types of events: over one-third became a geoscientist by randomly walking into an undergraduate class and finding themselves captivated by the topic and/or a dynamic instructor. The subject matter itself attracts another one-fourth, and family members encourage another one-fifth of geoscientists to initially enter the field. Slightly more women cite the first attractor of undergraduate class, but the principal draw for our future workforce, male and female, is good instruction of freshman courses. Retention of women in academia is another key issue. The proportion that considers leaving after working towards one or more degrees is highly skewed by gender: one-half of female and only one-third of male geoscientists considered leaving the field at some time in their career. The reasons for considering leaving also differ by gender. Males cite financial issues, including an uncertain job market. Females cite two principal reasons for considering leaving: family issues and difficulties with a graduate advisor. Strategies currently exist for "family issues", including stop-the-clock (of tenure for family needs), assignment shift, on-campus daycare facilities, and unflinching administrative support for such practices. Graduate advising is a learnable skill, and more attention needs to be paid to

  10. E-Government: Initiatives, Developments, and Issues.

    Science.gov (United States)

    Aldrich, Duncan; Bertot, John Carlo; McClure, Charles R.

    2002-01-01

    Provides a background of government efforts to incorporate telecommunication and computer technologies to improve government performance and enhance citizen access to government information and services. Describes this symposium issue which discusses key issues that affect the success and implementation of electronic government initiatives. (LRW)

  11. Ten years of subproteome investigations in lactic acid bacteria: A key for food starter and probiotic typing

    DEFF Research Database (Denmark)

    Mangiapane, E.; Mazzoli, R.; Pessione, A.

    2015-01-01

    " strains that can be employed in food making and as nutraceutical supplements for human health. Unfortunately, these techniques are not used as extensively as it should be wise. The present report describes the most significant results obtained by our research group in 10 years of study on subproteomes......The definition of safety and efficacy of food-employed bacteria as well as probiotic strains is a continuous, often unattended, challenge. Proteomic techniques such as 2DE, DIGE and LC/LC-MS/MS are suitable and powerful tools to reveal new aspects (positive and negative) of "known" and "unknown...... elucidated by analysis of cytosolic, membrane-enriched, surface and extracellular proteomes. The present review opens a window on a yet largely underexplored field and highlights the huge potential of subproteome investigations for more rational choice of microbial strains as food starters, probiotics...

  12. Litter decomposition and nutrient dynamics of ten selected tree ...

    African Journals Online (AJOL)

    Litter decomposition processes in tropical rainforests are still poorly understood. Leaf litter decomposition and nutrient dynamics of ten contrasting tree species, Entandraphragma utile, Guibourtia tessmannii, Klainedoxa gabonensis, Musanga cecropioides, Panda oleosa, Plagiostyles africana, Pterocarpus soyauxii, ...

  13. Ten new species of Daidalotarsonemus (Prostigmata: Tarsonemidae) from Costa Rica

    Science.gov (United States)

    Ten new tarsonemid species of the genus Daidalotarsonemus found on native plants in Costa Rica are described herein: Daidalotarsonemus alas sp. n. Ochoa, Rezende & Lofego; Daidalotarsonemus azofeifai sp. n. Ochoa, Rezende & Lofego; Daidalotarsonemus bauchani sp. n. Rezende, Ochoa & Lofego; Daidalota...

  14. Ten Thousand Islands National Wildlife Refuge: Comprehensive Conservation Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This Comprehensive Conservation Plan (CCP) was written to guide management on Ten Thousand Islands NWR for the next 15 years. This plan outlines the Refuge vision...

  15. The Trail Inventory of Ten Thousand Islands NWR [Cycle 2

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The purpose of this report is to create a baseline inventory of all non-motorized trails on Ten Thousand Islands National Wildlife Refuge. Trails in this inventory...

  16. Ten-Competence: Life-Long Competence Development and Learning

    NARCIS (Netherlands)

    Koper, Rob; Specht, Marcus

    2006-01-01

    Koper, R., & Specht, M. (2008). Ten-Competence: Life-Long Competence Development and Learning. In M-A. Cicilia (Ed.), Competencies in Organizational e-learning: concepts and tools (pp. 234-252). Hershey: IGI-Global.

  17. Managing mountain hardwoods - a ten-year appraisal

    Science.gov (United States)

    George R., Jr. Trimble

    1961-01-01

    Ten years ago - in 1949 - four 5-acre plots were established on the Fernow Experimental Forest near Parsons, West Virginia, to show the effects upon mountain hardwoods of each of four management treatments.

  18. Webometric Analysis of Top Ten Asian and Indian Universities

    OpenAIRE

    Jalal, Samir Kumar; Sutradhar, B; Mukhopadhyay, Parthasarathi

    2016-01-01

    The paper tries to assess all the existing ranking systems which are used to rank higher educational institutions. The aim of the paper is to provide sufficient background to design and develop a new ranking system for a country. An attempt has been taken to find out the reasons of low ranking of Indian universities with respect to the world university ranking through webometric analysis of top ten Indian and Asian universities. A comparative study of top Ten Indian Universities and Asian uni...

  19. Key Management in Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Ismail Mansour

    2015-09-01

    Full Text Available Wireless sensor networks are a challenging field of research when it comes to security issues. Using low cost sensor nodes with limited resources makes it difficult for cryptographic algorithms to function without impacting energy consumption and latency. In this paper, we focus on key management issues in multi-hop wireless sensor networks. These networks are easy to attack due to the open nature of the wireless medium. Intruders could try to penetrate the network, capture nodes or take control over particular nodes. In this context, it is important to revoke and renew keys that might be learned by malicious nodes. We propose several secure protocols for key revocation and key renewal based on symmetric encryption and elliptic curve cryptography. All protocols are secure, but have different security levels. Each proposed protocol is formally proven and analyzed using Scyther, an automatic verification tool for cryptographic protocols. For efficiency comparison sake, we implemented all protocols on real testbeds using TelosB motes and discussed their performances.

  20. How repeatable are the physiological effects of TENS?

    Science.gov (United States)

    Fernandez-Del-Olmo, Miguel; Alvarez-Sauco, Maria; Koch, Giacomo; Franca, Michele; Marquez, Gonzalo; Sanchez, Jose A; Acero, Rafael M; Rothwell, John C

    2008-08-01

    Several studies suggest that transcutaneous electrical stimulation (TENS) can have a variety of effects on the central nervous system (CNS). In this study, we tried to replicate the physiological effects of TENS and to explore its effects on intracortical circuits. We used transcranial magnetic stimulation (TMS) and spinal reflex testing to examine excitability of intracortical and spinal cord circuits before and after a 30-min period of TENS over the flexor carpi radialis (FCR) muscle. We measured the amplitude of TMS-evoked muscle responses (MEP), short interval intracortical inhibition (SICI), intracortical facilitation (ICF) and cortical antagonist inhibition (CAI) in flexor and extensor carpial radialis (FCR, ECR) muscles as well as spinal reciprocal inhibition (RI) and presynaptic inhibition (PI) from ECR to FCR. TENS had no significant effect on any of these measures apart from a reduction in median nerve induced facilitation of FCR when testing CAI. When compared with previous studies, our results suggest that the effects of TENS are highly variable and unreliable, likely by the difficulty in defining precise parameters of stimulation in individual subjects. Care should be taken in assuming that effects after TENS observed in small populations of subjects will apply equally to a wider population.

  1. US-Hungarian Relations Ten Years After 1956

    Directory of Open Access Journals (Sweden)

    Tibor Glant

    2016-10-01

    Full Text Available 1966, the tenth anniversary of the 1956 Revolution, was a key year in US–Hungarian relations. Diplomatic relations were raised from the lowest to the highest level, but suspicion and tension remained. Neither side knew what to expect from the other on account of the anniversary, the Vietnam War, economic and cultural negotiations, and the fate of Cardinal Mindszenty. A traditional diplomatic historical approach is supplemented here with cultural materials to present the full scale of contacts ranging from high political issues to the visit of Hollywood movie star Kirk Douglas in Budapest. First Secretary of the Legation for Press and Cultural Affairs Edward Alexander receives special attention, because he played a crucial role in the events of 1966. As press secretary, he helped calm Hungarian fears over what American journalists might report about the anniversary, while as cultural affairs officer he worked on documenting and expanding American cultural presence in Hungary. In the latter capacity, he opened the USIA Library at the Legation, fraternized with blacklisted painters of the Zuglói Kör [‘Zugló Circle’], monitored the Hungarian stage production of My Fair Lady, and reported on the publication of American literature in Hungarian.

  2. The Ten Commandments revisited: the Qualities of Good Library Space

    Directory of Open Access Journals (Sweden)

    Andrew McDonald

    2006-06-01

    Full Text Available An increasing diversity of imaginative new academic libraries are being constructed around the world, successfully combining exciting architectural expression, inspiring internal spaces and good functionality. Library managers must have a strong vision for the new library and this should inspire the design and the whole building process. This paper explores the key qualities of good learning space, whether in new or refurbished buildings. It is suggested that, ideally, learning space should be functional, adaptable, accessible, varied, interactive, conducive, environmentally suitable, safe and secure, efficient and suitable for information technology. New space should also have “oomph”, capturing the minds of users and the spirit of the university. These indicative issues should be discussed in the brief and throughout the planning process, and the priority given to them will depend on the mission and culture of the library. Greater attention is being given to daylight, natural ventilation, cultural artwork, noise management, security, disabled access, information skills training and provision for e-services. Planning is increasingly centred on people or the learner, emphasising the need for social, interactive and collaborative learning spaces as well as for traditional spaces for quiet study and reflection. Some libraries are joined-up with other services. The academic library is an enduring physical ‘place’, providing a blended, hybrid environment of traditional and electronic services crucial for the future of our universities and their communities.

  3. An assessment of ten ocean reanalyses in the polar regions

    Science.gov (United States)

    Uotila, Petteri

    2017-04-01

    Ocean reanalysis (ORA) combines observations either statistically or with a hydrodynamical model, to reconstruct historical changes in the ocean. Global and regional ORA products are increasingly used in polar research, but their quality remains to be systematically assessed. To address this, the Polar ORA Intercomparison Project (PORA-IP) has been established following on from the ORA-IP project (Balmaseda et al. 2015, with other papers in a special issue of Climate Dynamics). The PORA-IP is constituted under the COST EOS initiative with plans to review reanalyses products in both the Arctic and Antarctic, and is endorsed by YOPP - the Year of Polar Prediction project. Currently, the PORA-IP team consists of 21 researchers from 15 institutes and universities. The ORA-IP products with polar physics, such as sea ice, have been updated where necessary and collected in a public database. In addition to model output, available observational polar climatologies are collected and used in the assessments. Due to the extensive variety of products, this database should become a valuable resource outside the PORA-IP community. For a comprehensive evaluation of the ten ORA products (CGLORSv5, ECDA3.1, GECCO2, Glorys2v4, GloSea5_GO5, MOVEG2i, ORAP5, SODA3.3.1, TOPAZ4 and UR025.4) in the Arctic and Southern Oceans several specific diagnostics are assessed. The PORA-IP diagnostics target the following topics: hydrography; heat, salinity and freshwater content; ocean transports and surface currents; mixed layer depth; sea-ice concentration and thickness; and snow thickness over sea ice. Based on these diagnostics, ORA product biases against observed data and their mutual spread are quantified, and possible reasons for discrepancies discussed. So far, we have identified product outliers and evaluated the multi-model mean. We have identified the importance of the atmospheric forcing, air-ocean coupling protocol and sea-ice data assimilation for the product performance. Moreover, we

  4. Avoid costly litigation: ten steps to implementing lawful hiring practices.

    Science.gov (United States)

    Holmes, Judith H

    2004-01-01

    employment-related disputes that lead to costly litigation would never have arisen if the employer had implemented more effective employment practices. Hiring mistakes in particular cause many costly legal battles. This article identifies legal issues that precipitate litigation and suggests ten steps physicians can take to implement lawful hiring practices that will reduce the risk of costly employment suits while improving office efficiency, morale, and productivity. NOTE: This article is intended as an overview of lawful hiring strategies, and is not a substitute for legal advice from experienced employment counsel. Applicable laws vary from state to state and appropriate procedures may depend on specific factual situations. This article is not, and should not be construed as, legal advice.

  5. A certificateless public key encryption based return routability ...

    Indian Academy of Sciences (India)

    However, RRP has several security threats and issues. Subsequently, RRP was integrated with identity-based encryption for improvement of security. Nevertheless, it suffers from some limitations such as inherent key escrow problem, lack of key revocation, high computational load and latency while providing security.

  6. How the Ten Largest Corporations of the World Evolved in the Period 2014-2015

    Directory of Open Access Journals (Sweden)

    Sorin-George Toma

    2016-01-01

    Full Text Available The last decades have witnessed the emergence and development of the transnational phase ofcapitalism followed by the making of a transnational capitalist class. As key actors in today’s globaleconomy, more and more corporations, especially multinational and transnational, are in touch withone another than ever before in many sectors at a global scale. These corporations have become giantbusiness organizations and wealthy and very powerful structures all over the world. The aim of ourpaper is to present the evolution of the world’s ten largest corporations by their revenues and profits inthe period 2014-2015. Our research is based on a literature review.

  7. Emerging Issues for Cultural Tourism in Macau Fragen des Kultur-Toursmus in Macau

    Directory of Open Access Journals (Sweden)

    Hilary du Cros

    2009-04-01

    Full Text Available Recent research on achieving sustainable heritage tourism in Macau advocates a greater collaboration between tourism and heritage management authorities and the local community on reaching sustainable tourism goals. A key theme for Macau in the last ten years has been how the tension between the proponents for greater casino development versus those for cultural heritage product development has played out in government policies for heritage management, private sector tourism development and host community concerns about heritage protection and achieving quality tourism. The indirect influence of the central government on Macau Special Administrative Region’s (SAR’s policy development in relation to these topics in the last ten years will be discussed in this context using findings from three recent studies by the Institute For Tourism Studies (IFT and background information collected on government policy and community views. This paper will outline emerging issues regarding demand, supply, and impacts of cultural tourism with reference to findings from four recent research projects. Special reference will be made to over-use and under-use issues, authenticity, and the management of tourism impacts while enhancing visitor experience. Strategic planning and management of cultural tourism products will also be touched upon. Jüngste Forschungen zum Kultur- und Denkmal-Tourismus in Macau haben ergeben, dass einer stärkeren Zusammenarbeit zwischen den Verwaltungsbereichen Toursmus und Denkmalpflege sowie den lokalen Gemeinden große Bedeutung zukommt, um eine nachhaltige Förderung der Tourismus zu erzielen.

  8. Special issue: diagnostics of atmospheric pressure microplasmas

    Science.gov (United States)

    Bruggeman, Peter; Czarnetzki, Uwe; Tachibana, Kunihide

    2013-11-01

    In recent decades, a strong revival of non-equilibrium atmospheric pressure plasma studies has developed in the form of microplasmas. Microplasmas have typical scales of 1 mm or less and offer a very exciting research direction in the field of plasma science and technology as the discharge physics can be considerably different due to high collisionality and the importance of plasma-surface interaction. These high-pressure small-scale plasmas have a diverse range of physical and chemical properties. This diversity coincides with various applications including light/UV sources [1], material processing [2], chemical analysis [3], material synthesis [4], electromagnetics [5], combustion [6] and even medicine [7]. At atmospheric pressure, large scale plasmas have the tendency to become unstable due to the high collision rates leading to enhanced heating and ionization compared to their low-pressure counterparts. As low-pressure plasmas typically operate in reactors with sizes of tens of centimetres, scaling up the pressure to atmospheric pressure the size of the plasma reduces to typical sizes below 1 mm. A natural approach of stabilizing atmospheric pressure plasmas is thus the use of microelectrode geometries. Traditionally microplasmas have been produced in confined geometries which allow one to stabilize dc excited discharges. This stabilization is intrinsically connected to the large surface-to-volume ratio which enhances heat transfer and losses of charged and excited species to the walls. Currently challenging boundaries are pushed by producing microcavity geometries with dimensions of the order of 1 µm [8]. The subject of this special issue, diagnostics of microplasmas, is motivated by the many challenges in microplasma diagnostics in view of the complex chemistry and strong spatial (and even temporal) gradients of species densities and plasma properties. Atmospheric pressure plasmas have a very long history dating back more than 100 years, with early work of

  9. Sets, Subsets, and Dichotomous Keys

    Science.gov (United States)

    Cole, E. James

    1973-01-01

    Discusses the procedures that should be observed in constructing a dichotomous key. The keying exercise described was used as a laboratory activity in a biology course for elementary education majors, however it could be used in other courses. (JR)

  10. Key Concepts in Informatics: Algorithm

    Science.gov (United States)

    Szlávi, Péter; Zsakó, László

    2014-01-01

    "The system of key concepts contains the most important key concepts related to the development tasks of knowledge areas and their vertical hierarchy as well as the links of basic key concepts of different knowledge areas." (Vass 2011) One of the most important of these concepts is the algorithm. In everyday life, when learning or…

  11. Adolescent women as a key target population for community nutrition education programs in Indonesia.

    Science.gov (United States)

    Savage, Amy; Februhartanty, Judhiastuty; Worsley, Anthony

    2017-05-01

    Adolescence is a critical life-stage that sets the foundation for health in adulthood. Adolescent women are a unique population and should be targeted as such for nutrition promotion activities. Using Indonesia as a case study, this qualitative study aimed to identify existing nutrition promotion programs aimed at adolescent girls, how best to target this population and effective recommendations to inform nutrition education program design for this important group. Semi-structured interviews and questionnaires were conducted with ten key informants working in public health in Indonesia. Interview transcripts were analysed and coded to identify key themes. No existing nutrition education programs targeting adolescent women in Indonesia were identified. Several strategies apply to nutrition programs for adolescent girls: 1) nutrition promotion messages that are relevant to the lifestyles and interests of adolescent women; 2) technology-based interventions show promise, however, they need to be appropriately targeted to sub-groups; 3) school remains an important setting; and 4) early marriage is an important issue affecting nutritional status and engagement of adolescent girls. The informants recommended that: 1) more research is needed about the underlying motivations for behaviour change among adolescent women and ways to effectively implement the identified engagement strategies; 2) adolescent girls should be included in program design to improve its suitability and uptake; and 3) government budget and policy support is crucial to success. Adolescent women are an important population group and more research is required to identify the optimal forms of engagement to improve nutrition programs for them.

  12. Nonresponse Error in Mail Surveys: Top Ten Problems

    Directory of Open Access Journals (Sweden)

    Jeanette M. Daly

    2011-01-01

    Full Text Available Conducting mail surveys can result in nonresponse error, which occurs when the potential participant is unwilling to participate or impossible to contact. Nonresponse can result in a reduction in precision of the study and may bias results. The purpose of this paper is to describe and make readers aware of a top ten list of mailed survey problems affecting the response rate encountered over time with different research projects, while utilizing the Dillman Total Design Method. Ten nonresponse error problems were identified, such as inserter machine gets sequence out of order, capitalization in databases, and mailing discarded by postal service. These ten mishaps can potentiate nonresponse errors, but there are ways to minimize their frequency. Suggestions offered stem from our own experiences during research projects. Our goal is to increase researchers' knowledge of nonresponse error problems and to offer solutions which can decrease nonresponse error in future projects.

  13. Delaktighet i avstämningsmöten

    OpenAIRE

    Pia H. Bülow; Wilinska, Monika

    2014-01-01

    Den här rapporten handlar om de lagstadgade möten som kallas avstämningsmöten. Det är Försäkringskassan som kallar olika aktörer till dessa flerpartssamtal, för att utreda arbetsförmågan hos en sjukskriven person (här: försäkrad), och eventuella behov av rehabilitering för att denne ska kunna återgå till arbete. Syftet med det här redovisade forskningsprojektet var att studera den kommunikativa processen i sådana möten avseende främst de försäkrades delaktighet och upplevelse av mötet. Studie...

  14. Ten_m3 regulates eye-specific patterning in the mammalian visual pathway and is required for binocular vision.

    Directory of Open Access Journals (Sweden)

    Catherine A Leamey

    2007-09-01

    Full Text Available Binocular vision requires an exquisite matching of projections from each eye to form a cohesive representation of the visual world. Eye-specific inputs are anatomically segregated, but in register in the visual thalamus, and overlap within the binocular region of primary visual cortex. Here, we show that the transmembrane protein Ten_m3 regulates the alignment of ipsilateral and contralateral projections. It is expressed in a gradient in the developing visual pathway, which is consistently highest in regions that represent dorsal visual field. Mice that lack Ten_m3 show profound abnormalities in mapping of ipsilateral, but not contralateral, projections, and exhibit pronounced deficits when performing visually mediated behavioural tasks. It is likely that the functional deficits arise from the interocular mismatch, because they are reversed by acute monocular inactivation. We conclude that Ten_m3 plays a key regulatory role in the development of aligned binocular maps, which are required for normal vision.

  15. Time in powers of ten natural phenomena and their timescales

    CERN Document Server

    't Hooft, Gerard

    2014-01-01

    In this richly illustrated book, Nobel Laureate Gerard 't Hooft and Theoretical Physicist Stefan Vandoren describe the enormous diversity of natural phenomena that take place at different time scales. In the tradition of the bestseller Powers of Ten , the authors zoom in and out in time, each step with a factor of ten. Starting from one second, time scales are enlarged until processes are reached that take much longer than the age of the universe. After the largest possible eternities, the reader is treated to the shortest and fastest phenomena known. Then the authors increase with powers of t

  16. Security analysis of quantum key distribution on passive optical networks.

    Science.gov (United States)

    Lim, Kyongchun; Ko, Heasin; Suh, Changho; Rhee, June-Koo Kevin

    2017-05-15

    Needs for providing security to end users have brought installation of quantum key distribution (QKD) in one-to-many access networks such as passive optical networks. In the networks, a presence of optical power splitters makes issues for secure key rate more important. However, researches for QKD in access networks have mainly focused on implementation issues rather than protocol development for key rate enhancement. Since secure key rate is theoretically limited by a protocol, researches without protocol development cannot overcome the limit of secure key rate given by a protocol. This brings need of researches for protocol development. In this paper, we provide a new approach which provides secure key rate enhancement over the conventional protocol. Specifically, we propose the secure key rate formula in a passive optical network by extending the secure key rate formula based on the decoy-state BB84 protocol. For a passive optical network, we provide a way that incorporates cooperation across end users. Then, we show that the way can mitigate a photon number splitting (PNS) attack which is crucial in an well known decoy BB84 protocol. Especially, the proposed scheme enables multi-photon states to serve as secure keys unlike the conventional decoy BB84 protocol. Numerical simulations demonstrate that our proposed scheme outperforms the decoy BB84 protocol in secure key rate.

  17. Secure key storage and distribution

    Science.gov (United States)

    Agrawal, Punit

    2015-06-02

    This disclosure describes a distributed, fault-tolerant security system that enables the secure storage and distribution of private keys. In one implementation, the security system includes a plurality of computing resources that independently store private keys provided by publishers and encrypted using a single security system public key. To protect against malicious activity, the security system private key necessary to decrypt the publication private keys is not stored at any of the computing resources. Rather portions, or shares of the security system private key are stored at each of the computing resources within the security system and multiple security systems must communicate and share partial decryptions in order to decrypt the stored private key.

  18. Closer to zero: Reflections on ten years of ART rollout

    African Journals Online (AJOL)

    To reflect upon ten years of antiretroviral therapy. (ART) rollout, one really should set the clock back a little further to see the massive impact of ART on our lives – for clinicians and patients alike. My own journey with HIV began in 1999 when, as a young doctor, I decided to venture into private practice with a local general ...

  19. WISE Albedos for Tens of Thousands of Main Belt Asteroids

    NARCIS (Netherlands)

    Masiero, Joseph R.; Mainzer, A. K.; Bauer, J.; Cutri, R.; Dailey, J.; Delbo, M.; Grav, T.; McMillan, R. S.; Mueller, M.; Walker, R.; Wright, E.; WISE Science Team, [No Value

    2010-01-01

    Using thermal IR data from the Wide-field Infrared Survey Explorer (WISE) mission we have calculated diameters for tens of thousands of previously known Main Belt asteroids. Using archival optical observations we have also determined albedos for each object. We present our results from this

  20. Ten Indicators of Vitality in Smaller Academic Libraries

    Science.gov (United States)

    Pappas, David

    2009-01-01

    This paper provides a means of quickly ascertaining the relative health of smaller academic libraries by presenting a top ten list of vitality indicators. The list is based on an observational convenience sampling of thirty smaller academic libraries across the United States. The indicators making the list were those which appeared most often in…

  1. A ten-year histopathological study of generalised lymphadenopathy ...

    African Journals Online (AJOL)

    2010-07-31

    Jul 31, 2010 ... Original Research: A ten-year histopathological study of generalised lymphadenopathy in India. 267. Vol 53 No 3. S Afr Fam Pract 2011. Introduction. The body contains approximately 600 lymph nodes, but only those in the submandibular, axillary and inguinal regions may be palpable in healthy people.

  2. DIE APOSTOLAAT VAN DIE KERK IN HIERDIE TYD TEN OPSIGTE ...

    African Journals Online (AJOL)

    Test

    Hierdie verkondiging het net een doel en net een inhoud. Die doel ... is die vlees- geworde Woord, Christus. Die apostalaat is nie een funksie van die kerk tussen ander nie. Die kerk is apostel in alles wat hy is en doen. Die doel van die. 239 ... skawing, nie vir uitbreiding van politieke magssfere nie, ens. Selfs ten koste van ...

  3. Ten-year-olds' reflections on their life in preschool

    DEFF Research Database (Denmark)

    Broström, Stig

    2016-01-01

    What do children think of their time in preschool? In the present study, twelve ten-year-old children collected data from their classmates. The children tend to remember their friends, and reflect on what games they played and with whom. Only about one in three respondents even mentioned the day...

  4. A Design Taxonomy Utilizing Ten Major Evaluation Strategies.

    Science.gov (United States)

    Willis, Barry

    This paper discusses ten evaluation strategies selected on the basis of their general acceptance and their relatively unique approach to the field: (1) State, "Countenance of Evaluation"; (2) Stufflebeam, "Decision Centered Evaluation (CIPP)"; (3) Provus, "Discrepancy Evaluation"; (4) Scriven, "Goal Free Evaluation"; (5) Scriven, "Formative and…

  5. Technical descriptions of ten irrigation technologies for conserving energy

    Energy Technology Data Exchange (ETDEWEB)

    Harrer, B.J.; Wilfert, G.L.

    1983-05-01

    Technical description of ten technologies which were researched to save energy in irrigated agriculture are presented. These technologies are: well design and development ground water supply system optimization, column and pump redesign, variable-speed pumping, pipe network optimization, reduced-pressure center-pivot systems, low-energy precision application, automated gated-pipe system, computerized irrigation scheduling, and instrumented irrigation scheduling. (MHR)

  6. Effects of TENS and methylphenidate in tuberculous meningo-encephalistis

    NARCIS (Netherlands)

    Scherder, E.J.A.; Deursen, S.; Manen, S.R.; Ferenschild, K.C.M.P.

    2001-01-01

    Primary objective: Beneficial effects of transcutaneous electrical nerve stimulation (TENS) on cognition and behaviour were observed in a child with probable Herpes Simplex Encephalitis. Based on these positive findings, it was examined in the present case study whether a child who had been

  7. Ten Strengths of How Teachers Do Cooperative Learning

    Science.gov (United States)

    Jaocbs, George M.

    2016-01-01

    Cooperative learning involves students in working together with peers to learn, to develop learning skills and to enjoy the learning process. This paper examines ten areas in which the author believes he and other teachers do cooperative learning well. These areas are: (1) keeping group size small, usually four or fewer; (2) encouraging students…

  8. Ten Helpful Ideas for Teaching English to Young Learners

    Science.gov (United States)

    Shin, Joan Kang

    2006-01-01

    This article offers ten suggestions for teaching young learners between the age of 7 and 12 based on language-teaching principles. They include supplementing activities with visuals, realia and movement; involving students in making visuals and realia; moving from activity to activity; teaching in themes; using stories and contexts familiar to…

  9. Ten statistics commandments that almost never should be broken.

    Science.gov (United States)

    Knapp, Thomas R; Brown, Jean K

    2014-08-01

    Quantitative researchers must choose among a variety of statistical methods when analyzing their data. In this article, the authors identify ten common errors in how statistical techniques are used and reported in clinical research and recommend stronger alternatives. Useful references to the methodological research literature in which such matters are discussed are provided. © 2014 Wiley Periodicals, Inc.

  10. Mid-term evaluation of ten National Research schools

    DEFF Research Database (Denmark)

    Gustafsson, Göran; Dahl, Hanne Marlene; Gustafsson, Christina

    grant applications, monitoring the progress of the FORSKERSKOLER scheme and serving as the evaluation panel for the mid-term evaluation in 2013 and in 2016/2017. The task of the evaluation panel has been to: 1) evaluate the quality of and progress achieved by the ten research schools which were awarded...

  11. Ten years into the marshes – Hapalemur alaotrensis conservation ...

    African Journals Online (AJOL)

    This article describes the approach that Madagascar Wildlife Conservation has been implementing during the past ten years at Lake Alaotra, discussing the plan of action and challenges for environmental education, ecotourism and alternative livelihoods. Les problèmes de gestion des ressources naturelles impliquent ...

  12. Changes in users' Web search performance after ten years ...

    African Journals Online (AJOL)

    The changes in users' Web search performance using search engines over ten years was investigated in this study. Matched data obtained from samples in 2000 and 2010 were used for the comparative analysis. The patterns of Web search engine use suggested a dominance in using a particular search engine. Statistical ...

  13. A Survey of Ten Money and Banking Textbooks.

    Science.gov (United States)

    Amsler, Christine E.

    1985-01-01

    Ten college-level money and banking textbooks were arrayed along six continua representing professors' major preferences when choosing a text. The continua topics are theoretical approach, complexity of presentation, theory/institution mix, nuts and bolts explanations, organizational approach, and writing style. (RM)

  14. Phytochemical and Anticancer Studies on Ten Medicinal Plants ...

    African Journals Online (AJOL)

    Ten medicinal plants used in Nigerian ethno medicine were subjected to phytochemical and anticancer studies using established standard procedures. The result of the study revealed the presence of phytochemical constituents such as alkaloids, saponins, tannins and flavonoids. Anona muricata, Andrographis paniculata ...

  15. Does the Russian Economy Need Human Capital? Ten Doubts

    Science.gov (United States)

    Gimpelson, V. E.

    2016-01-01

    It is generally accepted that human capital is an important factor in economic growth, but its impact on growth depends on the demand for education and skills on the labor market. Demand for human capital is largely determined by the institutional environment that governs the basic conditions for economic activity. The author expresses ten doubts…

  16. Ten Challenges of the Amyloid Hypothesis of Alzheimer's Disease

    DEFF Research Database (Denmark)

    Kepp, Kasper Planeta

    2017-01-01

    The inability to effectively halt or cure Alzheimer's disease (AD), exacerbated by the recent failures of high-profile clinical trials, emphasizes the urgent need to understand the complex biochemistry of this major neurodegenerative disease. In this paper, ten central, current challenges...

  17. Molecular characterization of ten mango cultivars using simple ...

    African Journals Online (AJOL)

    DEAN

    2013-11-20

    Nov 20, 2013 ... Molecular characterization of ten mango cultivars using simple sequences repeat (SSR) markers. M. Kumar1*, V. Ponnuswami1, P. Nagarajan2, P. Jeyakumar3 and N. Senthil2. 1Horticultural College and Research Institute, Periyakulam, Tamil Nadu, 625604, India. 2Centre for Plant Molecular Biology, ...

  18. Ten Years after Columbine: The Tragedy of Youth Deepens

    Science.gov (United States)

    Giroux, Henry A.

    2009-01-01

    For young people it just gets worse. Ten years after the Columbine tragedy, the debate over school safety has clearly shown that educators, parents, politicians, and the mainstream media have created the conditions in which young people have increasingly become the victims of adult mistreatment, indifference, neglect, even violence. The tragic…

  19. Flow hydrodynamics near inlet key of Piano Key Weir (PKW)

    Indian Academy of Sciences (India)

    This paper presents fundamental outcomes from an experimental study on the hydrodynamic performance near inlet key of Piano Key Weir (PKW). Hydrodynamic performance was tested in a circulated open channel that comprised of PKW and sand bed (d50 = 0.25 mm). Instantaneous velocities were measured at 20 cross ...

  20. Key to good fit: body measurement problems specific to key ...

    African Journals Online (AJOL)

    In this manner, key dimensions were identified and defined. The results revealed that, although international descriptions are available for 100% of the key measurements, major problems seem to be experienced with landmarking, and with consensus about the measuring method and about landmarking. If one assumes ...

  1. KEY TOPICS IN SPORTS MEDICINE

    Directory of Open Access Journals (Sweden)

    Amir Ali Narvani

    2006-12-01

    Full Text Available Key Topics in Sports Medicine is a single quick reference source for sports and exercise medicine. It presents the essential information from across relevant topic areas, and includes both the core and emerging issues in this rapidly developing field. It covers: 1 Sports injuries, rehabilitation and injury prevention, 2 Exercise physiology, fitness testing and training, 3 Drugs in sport, 4 Exercise and health promotion, 5 Sport and exercise for special and clinical populations, 6 The psychology of performance and injury. PURPOSE The Key Topics format provides extensive, concise information in an accessible, easy-to-follow manner. AUDIENCE The book is targeted the students and specialists in sports medicine and rehabilitation, athletic training, physiotherapy and orthopaedic surgery. The editors are authorities in their respective fields and this handbook depends on their extensive experience and knowledge accumulated over the years. FEATURES The book contains the information for clinical guidance, rapid access to concise details and facts. It is composed of 99 topics which present the information in an order that is considered logical and progressive as in most texts. Chapter headings are: 1. Functional Anatomy, 2. Training Principles / Development of Strength and Power, 3. Biomechanical Principles, 4. Biomechanical Analysis, 5. Physiology of Training, 6. Monitoring of Training Progress, 7. Nutrition, 8. Hot and Cold Climates, 9. Altitude, 10. Sport and Travelling, 11. Principles of Sport Injury Diagnosis, 12. Principles of Sport and Soft Tissue Management, 13. Principles of Physical Therapy and Rehabilitation, 14. Principles of Sport Injury Prevention, 15. Sports Psychology, 16. Team Sports, 17. Psychological Aspects of Injury in Sport, 18. Injury Repair Process, 19. Basic Biomechanics of Tissue Injury, 20. Plain Film Radiography in Sport, 21. Nuclear Medicine, 22. Diagnostic Ultrasound, 23. MRI Scan, 24. Other Imaging, 5. Head Injury, 26. Eye

  2. Ethical issues in sport psychology.

    Science.gov (United States)

    Watson, Jack C; Way, William C; Hilliard, Robert C

    2017-08-01

    The field of sport psychology is dynamic and growing. To continue building credibility with the public and allied professionals, effective and ethical practice is crucial. Advances in technology have allowed sport psychology professionals to consult with athletes from a distance, but practitioners must be mindful of their competency to use technology, confidentiality concerns, and the suitability of technology for their clients. Movement toward defining competency and clarifying issues of title usage are additional areas in which the field is gaining momentum. Recent attention has also been drawn to the topics of professional development and cultural competency. With the unique settings in which applied sport psychology practice takes place, attention to multiple relationships is another key ethical issue. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. ON OPERATION OF 740 M LONG FREIGHT TRAINS ON CZECH TEN-T RAILWAY NETWORK

    Directory of Open Access Journals (Sweden)

    Michal Drábek

    2016-09-01

    Full Text Available Regulation (EU No 1315/2013 defines actual scope of core and comprehensive TEN-T network, including both networks for railway freight transport. For the core network, possibility to operate 740 m long freight trains is required. The aim of this paper is to analyse availability of appropriate overtaking tracks for 740 m long freight trains. Due to ETCS braking curves and odometry, such trains, after ETCS implementation, will require 780-800 m long overtaking tracks. For practical reasons (e.g. bypass lines, whole Czech railway TEN-T network is analysed. The overtaking track, whose occupation means influence on scheduled traffic or threat to boarding passengers, are excluded. The data was collected from station schemes from Collection of Official Requisites for 2015/16 Timetable, issued by SŽDC, Czech state Infrastructure Manager. Most of appropriate tracks are over 800 m long, but their density in the network and in particular directions varies considerably. For freight traffic, gradient of the line is important, so in the resulting figure, there are marked significant peaks for particular lines as well. Czech TEN-T lines are further segmented on the basis of number of tracks and their traffic character. Then, specific issues on overtaking or crossing of 740 m long freight trains are discussed. As a conclusion, for long-term development of Czech TEN-T lines, targeted investment is recommended not only for passenger railway, but also for freight railway. An attractive capacity offer for railway undertakings, which can stimulate freight traffic on European Rail freight corridors, can be represented by network-bound periodic freight train paths with suitable long overtaking tracks outside bottlenecks. After the overtaking by passenger trains, a freight train should run without stop through large node station or a bottleneck area. Before the sections with high gradients, coupling of additional locomotives should be connected with the overtaking

  4. Ethical issues in animal cloning.

    Science.gov (United States)

    Fiester, Autumn

    2005-01-01

    The issue of human reproductive cloning has recently received a great deal attention in public discourse. Bioethicists, policy makers, and the media have been quick to identify the key ethical issues involved in human reproductive cloning and to argue, almost unanimously, for an international ban on such attempts. Meanwhile, scientists have proceeded with extensive research agendas in the cloning of animals. Despite this research, there has been little public discussion of the ethical issues raised by animal cloning projects. Polling data show that the public is decidedly against the cloning of animals. To understand the public's reaction and fill the void of reasoned debate about the issue, we need to review the possible objections to animal cloning and assess the merits of the anti-animal cloning stance. Some objections to animal cloning (e.g., the impact of cloning on the population of unwanted animals) can be easily addressed, while others (e.g., the health of cloned animals) require more serious attention by the public and policy makers.

  5. Global quality imaging: emerging issues.

    Science.gov (United States)

    Lau, Lawrence S; Pérez, Maria R; Applegate, Kimberly E; Rehani, Madan M; Ringertz, Hans G; George, Robert

    2011-07-01

    Quality imaging may be described as "a timely access to and delivery of integrated and appropriate procedures, in a safe and responsive practice, and a prompt delivery of an accurately interpreted report by capable personnel in an efficient, effective, and sustainable manner." For this article, radiation safety is considered as one of the key quality elements. The stakeholders are the drivers of quality imaging. These include those that directly provide or use imaging procedures and others indirectly supporting the system. Imaging is indispensable in health care, and its use has greatly expanded worldwide. Globalization, consumer sophistication, communication and technological advances, corporatization, rationalization, service outsourcing, teleradiology, workflow modularization, and commoditization are reshaping practice. This article defines the emerging issues; an earlier article in the May 2011 issue described possible improvement actions. The issues that could threaten the quality use of imaging for all countries include workforce shortage; increased utilization, population radiation exposure, and cost; practice changes; and efficiency drive and budget constraints. In response to these issues, a range of quality improvement measures, strategies, and actions are used to maximize the benefits and minimize the risks. The 3 measures are procedure justification, optimization of image quality and radiation protection, and error prevention. The development and successful implementation of such improvement actions require leadership, collaboration, and the active participation of all stakeholders to achieve the best outcomes that we all advocate. Copyright © 2011 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  6. Thermal fatigue issues in high-gradient particle accelerators

    CERN Document Server

    Heikkinen, Samuli Tapio; Neupert, Holger

    2006-01-01

    The CLIC (Compact LInear Collider) is being studied at CERN (European Organization for Nuclear Research) as a possible future high-energy (0.5-5 TeV centre-of-mass) physics facility. The current aim of the CLIC Study Team is to demonstrate the key feasibility issues before 2010. CLIC will be about 33 kilometers long and will be buried 100 meters underground. The main linac of CLIC consists of accelerating structures with the following demanding performance requirements: accelerating gradients of about 150 MV/m, power flows of about 200 MW, 1-2 ìm dimensional tolerances, an optical-quality surface finish and ultimately a low mass production cost. About 80% of CLIC's 33 kilometer length will be filled with main beam accelerating structures, which will require of the order of ten thousand tons of raw material and millions of individual parts. One of the main limiting factors of the main linac accelerating structures is the thermal fatigue due to the pulsed surface heating. The accelerating RFpower pulses heat u...

  7. ISSUES OF FETUS DRUG SAFETY

    Directory of Open Access Journals (Sweden)

    A.V. Ostrovskaya

    2010-01-01

    Full Text Available The article is focused on the issue of fetus drug safety. Development of a child’s health depends both on hereditary information and environment factors. The reason for deviation from the process of normal prenatal development could be any xenobiotics, physical factors and some medications having a pathogenic effect during pregnancy on the embryo and fetus. Due to that, the physician’s preventive work based on the knowledge of embryogenesis processes and critical development periods. Key words: teratogenic action, medications, prenatal development, congenital malformation, newborns, children.(Pediatric Pharmacology. – 2010; 7(1:25-28

  8. Psychiatric disorders and sleep issues.

    Science.gov (United States)

    Sutton, Eliza L

    2014-09-01

    Sleep issues are common in people with psychiatric disorders, and the interaction is complex. Sleep disorders, particularly insomnia, can precede and predispose to psychiatric disorders, can be comorbid with and exacerbate psychiatric disorders, and can occur as part of psychiatric disorders. Sleep disorders can mimic psychiatric disorders or result from medication given for psychiatric disorders. Impairment of sleep and of mental health may be different manifestations of the same underlying neurobiological processes. For the primary care physician, key tools include recognition of potential sleep effects of psychiatric medications and familiarity with treatment approaches for insomnia in depression and anxiety. Copyright © 2014 Elsevier Inc. All rights reserved.

  9. Logistics in Namibia: Issues and challenges

    National Research Council Canada - National Science Library

    Savage, Christopher J; Fransman, Logan; Jenkins, Andrew K

    2013-01-01

    ... stakeholders' views on the current state of the Namibian logistics industry? * What are the principal logistical issues in the stakeholder's firm or organisation? * What do stakeholders believe are the barriers and key issues affecting the operations and development of the logistics industry in Namibia? * What are stakeholders' views on the sustainability of the Namibian logistics sector? For this research, the stakeholders identified were users, logistics companies, freight forwarders, the Namibian state, logistics s...

  10. Portugal—Selected Issues

    OpenAIRE

    International Monetary Fund

    1998-01-01

    This Selected Issues paper on Portugal reviews a set of issues of relevance to the regime change implied by European Monetary Union participation. It presents an empirical investigation of the business cycle in Portugal. The paper attempts to obtain a quantitative sense of the impact of monetary policy on the Portuguese economy, utilizing an unrestricted vector autoregression methodology to characterize the monetary transmission mechanism. It also examines some key forces at work in Portugalâ...

  11. Trade and Environmental Issues in Forest Production

    OpenAIRE

    Markku Simula

    1999-01-01

    This paper is an attempt to clarify some of the key issues on trade and environment in the forestry sector. The two main emerging issues in the international trade of forest products within Latin America and the Caribbean to be studied are: 1) implications of the removal of trade barriers for the economic contribution and sustainability of production of the forest sector; and 2) prospects for "green" markets and eco-labelling of forest products based on improved management and harvesting prac...

  12. [THE TEN MOST CITED ARTICLES OF THE JOURNAL "NUTRICION HOSPITALARIA"].

    Science.gov (United States)

    Franco-López, Ángeles; González-Gallego, Javier; Sanz-Valero, Javier; Tuñón, María Jesús; García-De-Lorenzo, Abelardo; Culebras, Jesús M

    2015-12-01

    After 36 years of continued publication of the journal Nutrición Hospitalaria, a list with the ten most cited articles published in it is elaborated. The top ten most cited articles in the world literature and stratification according to language, English or Spanish, subject, or period of time published are also analyzed. Nutr Hosp is the most important Ibero latin American nutrition journal. Nutr Hosp published 369 items in 2014 gaining the fourth position among all the world's journals devoted to nutrition. Article publication in English, or simultaneously in Spanish and English and Open Access policy probably benefit the number of citations. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  13. Childhood herpes zoster: A clustering of ten cases

    Directory of Open Access Journals (Sweden)

    Prabhu Smitha

    2009-01-01

    Full Text Available Herpes zoster occurs due to reactivation of the latent varicella zoster virus and is usually a disease of the elderly. Childhood herpes zoster is believed to be rare, though recent studies suggest increasing incidence in children. Here we report ten cases of childhood herpes zoster, seven of which occurred within a short span of six months, at a tertiary care level hospital in Pokhara, Nepal. Only three of the ten children reported previous history of varicella infection and none was immunized against varicella. Though childhood herpes zoster accounted for less than 1% of the total zoster cases in the past, recent reports show an increase in the number of cases in apparently healthy children. So far, no studies have been done linking childhood herpes zoster with HIV, though there are many studies linking it with other immunocompromised conditions.

  14. Clinical alarm hazards: a "top ten" health technology safety concern.

    Science.gov (United States)

    Keller, James P

    2012-01-01

    For the past several years ECRI Institute has published a list of Top Ten Health Technology Hazards. This list is based on ECRI's extensive research in health technology safety and on data provided to its problemreporting systems. For every year that the Top Ten list has been published, Alarm Hazards have been at or near the top of the list. Improving alarm safety requires a systematic review of a hospital's alarm-based technologies and analysis of alarm management policies like alarm escalation strategies and staffing patterns. It also requires careful selection of alarm setting criteria for each clinical care area. This article will overview the clinical alarm problems that have been identified through ECRI Institute's research and analysis of various problem reporting databases, including those operated by ECRI Institute. It will also highlight suggestions for improvement, particularly from a technology design and technology management perspective. Copyright © 2012 Elsevier Inc. All rights reserved.

  15. The Ten Commandments tra Vecchio e Nuovo Testamento

    Directory of Open Access Journals (Sweden)

    De Berti Raffaele

    2011-06-01

    Full Text Available Cecil B. DeMille adapted for the screen the biblical text of Exodus twice, and in both cases he devised sophisticated strategies for intersemiotic translation with the aim to create a great show for a popular Christian audience. This is the reason why The Ten Commandments cannot be considered a mere illustration of the biblical story but instead a complex fiction film, which uses the Bible only as a starting point.

  16. The Ten Commandments tra Vecchio e Nuovo Testamento

    OpenAIRE

    De Berti Raffaele; Tomaso Subini

    2011-01-01

    Cecil B. DeMille adapted for the screen the biblical text of Exodus twice, and in both cases he devised sophisticated strategies for intersemiotic translation with the aim to create a great show for a popular Christian audience. This is the reason why The Ten Commandments cannot be considered a mere illustration of the biblical story but instead a complex fiction film, which uses the Bible only as a starting point.

  17. Ten inherited disorders in purebred dogs by functional breed groupings

    OpenAIRE

    Oberbauer, A. M.; Belanger, J. M.; Bellumori, T.; BANNASCH, D. L.; Famula, T R

    2015-01-01

    Background Analysis of 88,635 dogs seen at the University of California, Davis Veterinary Medical Teaching Hospital from 1995 to 2010 identified ten inherited conditions having greater prevalence within the purebred dog population as compared to the mixed-breed dog population: aortic stenosis, atopy/allergic dermatitis, gastric dilatation volvulus (GDV), early onset cataracts, dilated cardiomyopathy, elbow dysplasia, epilepsy, hypothyroidism, intervertebral disk disease (IVDD), and hepatic po...

  18. Fundamental Field Theory in Ten Dimensions and The Early Universe

    OpenAIRE

    Patwardhan, Ajay

    2006-01-01

    A unified field theory in ten dimensions, of all interactions, can describe high energy processes occuring in the early universe. In such a theory transitions that give properties of the universe can occur due to the presence of algebraic and geometric structures. A correspondence between theory and observations of the universe is made, to obtain a new interpretation and properties. This paper consists of a field theory and cosmological model of dark and normal energy and matter, cosmological...

  19. The African Association for Lexicography: After Ten Years

    OpenAIRE

    Mariëtta Alberts

    2011-01-01

    ABSTRACT: This year it has been ten years since the establishment of AFRILEX. After an expla-nation of what led to its forming, this article gives a short overview of its composition and activi-ties.


    Keywords: AFRICAN ASSOCIATION FOR LEXICOGRAPHY (AFRILEX), AFRICAN LAN-GUAGES ASSOCIATION OF SOUTH AFRICA (ALASA), BUREAU OF THE WOORDEBOEK VAN DIE AFRIKAANSE TAAL (WAT), DICTIONARY OF SOUTH AFRICAN ENGLISH (DSAE), LINGUISTIC ASSOCIATION OF SOUTHERN AFRICA (L...

  20. Quantitation of Ten Flavor Compounds in Unburned Tobacco Products†

    OpenAIRE

    Lisko, Joseph G.; Stanfill, Stephen B.; Watson, Clifford H.

    2014-01-01

    Most research on unburned tobacco has focused on the harmful chemicals associated with the tobacco itself. However, certain flavor additives in tobacco products can pose additional health risks. Flavors like camphor, coumarin, pulegone, eugenol, methyl salicylate, menthol and diphenyl ether have exhibited biological activity and/or toxicity in both lab animals and humans. This publication presents a new GC/MS method for the quantitation of ten flavor compounds (eucalyptol, camphor, menthol, p...