WorldWideScience

Sample records for technology-based treatment requirements

  1. Technology-based interventions in the treatment of overweight and obesity: A systematic review.

    Science.gov (United States)

    Raaijmakers, Lieke C H; Pouwels, Sjaak; Berghuis, Kim A; Nienhuijs, Simon W

    2015-12-01

    The prevalence of obesity increases worldwide. The use of technology-based interventions can be beneficial in weight loss interventions. This review aims to provide insight in the effectiveness of technology-based interventions on weight loss and quality of life for patients suffering overweight or obesity compared to standard care. Pubmed, PsycInfo, Web of Science, ScienceDirect, CINAHL and Embase were searched from the earliest date (of each database) up to February 2015. Interventions needed to be aimed at reducing or maintaining weight loss in persons with a body mass index (BMI) ≥ 25 kg/m(2) and have a technology aspect. Cochrane Collaboration's tool for assessing risk of bias was used for rating the methodological quality. Twenty-seven trials met inclusion criteria. Thirteen studies showed significant effects on weight loss compared to controls. Most interventions used a web-based approach (42%). Interventions were screened for five technical key components: self-monitoring, counsellor feedback and communication, group support, use of a structured program and use of an individually tailored program. All interventions that used a combination of all five or four components showed significant decreases in weight compared to controls. No significant results for quality of life were found. Outcomes on program adherence were reported in six studies. No significant results were found between weight loss and program adherence. Evidence is lacking about the optimal use of technology in weight loss interventions. However, when the optimal combination of technological components is found, technology-based interventions may be a valid tool for weight loss. Furthermore, more outcomes on quality of life and information about the effect of technology-based intervention after bariatric surgery are needed.

  2. 40 CFR 125.3 - Technology-based treatment requirements in permits.

    Science.gov (United States)

    2010-07-01

    ... toxicity (e.g., “the LC50 for fat head minnow of the effluent from outfall 001 shall be greater than 25... discussion of additional or more stringent effluent limitations and conditions.) Permits shall contain the...) For POTW's, effluent limitations based upon: (i) Secondary treatment—from date of permit issuance;...

  3. 7 CFR 305.5 - Treatment requirements.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Treatment requirements. 305.5 Section 305.5... SERVICE, DEPARTMENT OF AGRICULTURE PHYTOSANITARY TREATMENTS Chemical Treatments § 305.5 Treatment requirements. (a) Certified facility. The fumigation treatment facility must be certified by APHIS. Facilities...

  4. Evaluation of drinking water treatment combined filter backwash water recycling technology based on comet and micronucleus assay.

    Science.gov (United States)

    Chen, Ting; Xu, Yongpeng; Liu, Zhiquan; Zhu, Shijun; Shi, Wenxin; Cui, Fuyi

    2016-04-01

    Based on the fact that recycling of combined filter backwash water (CFBW) directly to drinking water treatment plants (WTP) is considered to be a feasible method to enhance pollutant removal efficiency, we were motivated to evaluate the genotoxicity of water samples from two pilot-scale drinking water treatment systems, one with recycling of combined backwash water, the other one with a conventional process. An integrated approach of the comet and micronucleus (MN) assays was used with zebrafish (Danio rerio) to investigate the water genotoxicity in this study. The total organic carbon (TOC), dissolved organic carbon (DOC), and trihalomethane formation potential (THMFP), of the recycling process were lower than that of the conventional process. All the results showed that there was no statistically significant difference (P>0.05) between the conventional and recycling processes, and indicated that the genotoxicity of water samples from the recycling process did not accumulate in 15 day continuous recycling trial. It was worth noting that there was correlation between the concentrations of TOC, DOC, UV254, and THMFPs in water and the DNA damage score, with corresponding R(2) values of 0.68, 0.63, 0.28, and 0.64. Nevertheless, both DNA strand breaks and MN frequency of all water samples after disinfection were higher than that of water samples from the two treatment units, which meant that the disinfection by-products (DBPs) formed by disinfection could increase the DNA damage. Both the comet and MN tests suggest that the recycling process did not increase the genotoxicity risk, compared to the traditional process.

  5. Technology based Education System

    DEFF Research Database (Denmark)

    Kant Hiran, Kamal; Doshi, Ruchi; Henten, Anders

    2016-01-01

    Abstract - Education plays a very important role for the development of the country. Education has multiple dimensions from schooling to higher education and research. In all these domains, there is invariably a need for technology based teaching and learning tools are highly demanded in the acad...

  6. Does gingival recession require surgical treatment?

    OpenAIRE

    Chan, Hsun-Liang; Chun, Yong-Hee Patricia; MacEachern, Mark

    2015-01-01

    Gingival recession represents a clinical condition in adults frequently encountered in the general dental practice. It is estimated that 23% of adults in the US have one or more tooth surfaces with ≥ 3 mm gingival recession. Clinicians often time face dilemmas of whether or not to treat such a condition surgically. Therefore, we were charged by the editorial board to answer this critical question: “Does gingival recession require surgical treatment?” An initial condensed literature search was...

  7. Does gingival recession require surgical treatment?

    Science.gov (United States)

    Chan, Hsun-Liang; Chun, Yong-Hee Patricia; MacEachern, Mark

    2016-01-01

    Gingival recession represents a clinical condition in adults frequently encountered in the general dental practice. It is estimated that 23% of adults in the US have one or more tooth surfaces with ≥ 3 mm gingival recession. Clinicians often time face dilemmas of whether or not to treat such a condition surgically. Therefore, we were charged by the editorial board to answer this critical question: “Does gingival recession require surgical treatment?” An initial condensed literature search was performed using a combination of gingival recession and surgery controlled terms and keywords. An analysis of the search results highlights our limited understanding of the factors that often guide the treatment of gingival recession. Understanding the etiology, prognosis and treatment of gingival recession continues to offer many unanswered questions and challenges in the field of periodontics as we strive to provide the best care possible for our patients. PMID:26427577

  8. Treatment of wastewater and restoration of aquatic systems through an eco-technology based constructed treatment wetlands - a successful experience in Central India.

    Science.gov (United States)

    Billore, S K; Sharma, J K; Singh, N; Ram, H

    2013-01-01

    In the last couple of decades constructed wetlands (CWs) have drawn considerable interest in Central India. CWs offer an effective means of integrating wastewater treatment and resource enhancement, often at competitive cost in comparison to conventional wastewater treatments, with additional benefits of Green Urban Landscaping and wildlife habitat. This paper describes treatment performances and the design of some Sub Surface Flow CWs (SSFCW) and Artificial Floating Islands (AFIs) in Central India. Central Indian CWs show significant pollution reduction load for total suspended solids (TSS) (62-82%), biochemical oxygen demand (BOD) (40-75%), NH(4)-N (67-78%) and total Kjeldahl nitrogen (TKN) (59-78%). Field scale SSFCWs installed so far in Central India are rectangular, earthen, single/multiple celled having similar depths of 0.60-0.90 m, hydraulic retention capacity 18-221 m(3) with effective size 41.8-1,050 m(2). The major components of CWs incorporate puddled bottom/side walls, sealed with impermeable low-density polyethylene, a bed of locally available river gravel planted with Phragmites karka, and an inlet distribution and outlet collection system. A new variant on CWs are AFIs working under hydroponics. The field scale experimental AFIs installed in-situ in a slowly flowing local river were composed of hollow bamboo, a bed of coconut coir, floating arrangements and Phragmites karka as nutrient stripping plant species. The AFIs polish the aquatic system by reducing 46.6% of TSS, 45-55% of NH(4)-N, 33-45% of NO(3)-N, 45-50% of TKN and 40-50% of BOD. The study established that there is a need for further research and sufficient data to assist the development of CWs by instilling confidence in policymakers, planners and in the public.

  9. 基于需求级软件复用技术研究%Studies on software reuse technology based on requirement level

    Institute of Scientific and Technical Information of China (English)

    张晓燕

    2011-01-01

    At present,the success ratio and the productivity in our country's software development are very low,which have restricted the development of our country's software industry seriously.The two challenging problems in software engineering are the inaccuracy of demand analysis and low level of software reusability,which lead to the current situation.To solve these two problems,the idea of realizing requirement level's software reuse is proposed by constructing a software requirement management system based on domain-specific ontology.In this paper,the background of the solution of this project is elaborated.Ontology extraction model and a software development model are put forward.Finally the innovation of the solution is pointed out.%目前我国软件项目开发的成功率和生产率都还很低,其中需求分析不准确和软件复用程度低严重制约了我国软件产业的良性发展。为了提高需求分析的准确度及软件复用程度,提出了通过构建面向领域本体的软件需求管理系统来实现需求级软件复用的解决方案。文中阐述了此方案的提出背景,提出了领域本体提取模型及软件开发过程模型,最后指出了此解决方案的创新之处。

  10. Technology base for microgravity horticulture

    Science.gov (United States)

    Sauer, R. L.; Magnuson, J. W.; Scruby, R. R.; Scheld, H. W.

    1987-01-01

    Advanced microgravity plant biology research and life support system development for the spacecraft environment are critically hampered by the lack of a technology base. This inadequacy stems primarily from the fact that microgravity results in a lack of convective currents and phase separation as compared to the one gravity environment. A program plan is being initiated to develop this technology base. This program will provide an iterative flight development effort that will be closely integrated with both basic science investigations and advanced life support system development efforts incorporating biological processes. The critical considerations include optimum illumination methods, root aeration, root and shoot support, and heat rejection and gas exchange in the plant canopy.

  11. 40 CFR 141.83 - Source water treatment requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Source water treatment requirements... water treatment requirements. Systems shall complete the applicable source water monitoring and... monitoring (§ 141.88(d)). (b) Description of source water treatment requirements—(1) System...

  12. 7 CFR 305.15 - Treatment requirements.

    Science.gov (United States)

    2010-01-01

    ... within the cold treatment facility, and other trapping methods, including Jackson/methyl eugenol and Mc..., including Jackson/methyl eugenol and McPhail traps, must be used within the 4 square miles surrounding the... other trapping methods, including Jackson/methyl eugenol and McPhail traps, must be used within the...

  13. Estimating costs and manpower requirements for conventional wastewater treatment facilities

    National Research Council Canada - National Science Library

    Patterson, W.L; Banker, R.F

    1971-01-01

    Data for estimating average construciton costs, operation and maintenance costs, and manpower staffing requirements, are presented for conventional wastewater treatment plants ranging from 1 to 100...

  14. Energy requirements for waste water treatment.

    Science.gov (United States)

    Svardal, K; Kroiss, H

    2011-01-01

    The actual mathematical models describing global climate closely link the detected increase in global temperature to anthropogenic activity. The only energy source we can rely on in a long perspective is solar irradiation which is in the order of 10,000 kW/inhabitant. The actual primary power consumption (mainly based on fossil resources) in the developed countries is in the range of 5 to 10 kW/inhabitant. The total power contained in our nutrition is in the range of 0.11 kW/inhabitant. The organic pollution of domestic waste water corresponds to approximately 0.018 kW/inhabitant. The nutrients contained in the waste water can also be converted into energy equivalents replacing market fertiliser production. This energy equivalent is in the range of 0.009 kW/inhabitant. Hence waste water will never be a relevant source of energy as long as our primary energy consumption is in the range of several kW/inhabitant. The annual mean primary power demand of conventional municipal waste water treatment with nutrient removal is in the range of 0.003-0.015 kW/inhabitant. In principle it is already possible to reduce this value for external energy supply to zero. Such plants should be connected to an electrical grid in order to keep investment costs low. Peak energy demand will be supported from the grid and surplus electric energy from the plant can be is fed to the grid. Zero 'carbon footprint' will not be affected by this solution. Energy minimisation must never negatively affect treatment efficiency because water quality conservation is more important for sustainable development than the possible reduction in energy demand. This argument is strongly supported by economical considerations as the fixed costs for waste water infrastructure are dominant.

  15. FY04 Engineering Technology Reports Technology Base

    Energy Technology Data Exchange (ETDEWEB)

    Sharpe, R M

    2005-01-27

    Lawrence Livermore National Laboratory's Engineering Directorate has two primary discretionary avenues for its investment in technologies: the Laboratory Directed Research and Development (LDRD) program and the ''Tech Base'' program. This volume summarizes progress on the projects funded for technology-base efforts in FY2004. The Engineering Technical Reports exemplify Engineering's more than 50-year history of researching and developing (LDRD), and reducing to practice (technology-base) the engineering technologies needed to support the Laboratory's missions. Engineering has been a partner in every major program and project at the Laboratory throughout its existence, and has prepared for this role with a skilled workforce and technical resources. This accomplishment is well summarized by Engineering's mission: ''Enable program success today and ensure the Laboratory's vitality tomorrow''. LDRD is the vehicle for creating those technologies and competencies that are cutting edge. These require a significant level of research or contain some unknown that needs to be fully understood. Tech Base is used to apply those technologies, or adapt them to a Laboratory need. The term commonly used for Tech Base projects is ''reduction to practice''. Tech Base projects effect the natural transition to reduction-to-practice of scientific or engineering methods that are well understood and established. They represent discipline-oriented, core competency activities that are multi-programmatic in application, nature, and scope. The objectives of technology-base funding include: (1) the development and enhancement of tools and processes to provide Engineering support capability, such as code maintenance and improved fabrication methods; (2) support of Engineering science and technology infrastructure, such as the installation or integration of a new capability; (3) support for technical and

  16. Medical Technology Base Master Plan

    Science.gov (United States)

    1990-03-01

    action of candidate mnedical1 countermeasures - Analysis and characterization of candidate compounds and their inetabolites - Application of molecular ...expected that research in molecular biology will lead to medical ,.vphylaes and treatments that ofter improved speclicity and potency, thus increasing...Disease Hazards Research (Inlectious Disease, Medical Biologia Defense, and Military AIDS), Conbat Casualty Care Research, Medical Chem"ca Defense Research

  17. Treatment Planning Systems for BNCT Requirements and Peculiarities

    CERN Document Server

    Daquino, G G

    2003-01-01

    The main requirements and peculiarities expected from the BNCT-oriented treatment planning system (TPS) are summarized in this paper. The TPS is a software, which can be integrated or composed by several auxiliary programs. It plays important roles inside the whole treatment planning of the patient's organ in BNCT. However, the main goal is the simulation of the irradiation, in order to obtain the optimal configuration, in terms of neutron spectrum, patient positioning and dose distribution in the tumour and healthy tissues. The presence of neutrons increases the level of complexity, because much more nuclear reactions need to be monitored and properly calculated during the simulation of the patient's treatment. To this purposes several 3D geometry reconstruction techniques, generally based on the CT scanning data, are implemented and Monte Carlo codes are normally used. The TPSs are expected to show also the results (basically doses and fluences) in a proper format, such as isocurves (or isosurfaces) along t...

  18. Evaluation of wastewater treatment requirements for thermochemical biomass liquefaction

    Energy Technology Data Exchange (ETDEWEB)

    Elliott, D C [Pacific Northwest Lab., Richland, WA (United States)

    1992-04-01

    Biomass can provide a substantial energy source. Liquids are preferred for use as transportation fuels because of their high energy density and handling ease and safety. Liquid fuel production from biomass can be accomplished by any of several different processes including hydrolysis and fermentation of the carbohydrates to alcohol fuels, thermal gasification and synthesis of alcohol or hydrocarbon fuels, direct extraction of biologically produced hydrocarbons such as seed oils or algae lipids, or direct thermochemical conversion of the biomass to liquids and catalytic upgrading to hydrocarbon fuels. This report discusses direct thermochemical conversion to achieve biomass liquefaction and the requirements for wastewater treatment inherent in such processing. 21 refs.

  19. Technology-based Mergers and Acquisitions

    DEFF Research Database (Denmark)

    Wang, Daojuan; Moini, Hamid

    2014-01-01

    The purpose of this chapter is to provide an updated review of what is known about the performance of technology-based mergers and acquisitions (TBM&As) and their determinants. This review brings together papers published from 1990 to 2012 in top-rated academic journals within nearly all fields...

  20. Technology-based Mergers and Acquisitions

    DEFF Research Database (Denmark)

    Wang, Daojuan; Moini, Hamid

    2014-01-01

    The purpose of this chapter is to provide an updated review of what is known about the performance of technology-based mergers and acquisitions (TBM&As) and their determinants. This review brings together papers published from 1990 to 2012 in top-rated academic journals within nearly all fields...

  1. 40 CFR 141.712 - Unfiltered system Cryptosporidium treatment requirements.

    Science.gov (United States)

    2010-07-01

    ... Cryptosporidium, Giardia lamblia, or viruses. ... systems must meet the combined Cryptosporidium inactivation requirements of this section and Giardia lamblia and virus inactivation requirements of § 141.72(a) using a minimum of two disinfectants, and...

  2. Treatment Process Requirements for Waters Containing Hydraulic Fracturing Chemicals

    Science.gov (United States)

    Stringfellow, W. T.; Camarillo, M. K.; Domen, J. K.; Sandelin, W.; Varadharajan, C.; Cooley, H.; Jordan, P. D.; Heberger, M. G.; Reagan, M. T.; Houseworth, J. E.; Birkholzer, J. T.

    2015-12-01

    A wide variety of chemical additives are used as part of the hydraulic fracturing (HyF) process. There is concern that HyF chemicals will be released into the environment and contaminate drinking water, agricultural water, or other water used for beneficial purposes. There is also interest in using produced water (water extracted from the subsurface during oil and gas production) for irrigation and other beneficial purposes, especially in the arid Southwest US. Reuse of produced water is not speculative: produced water can be low in salts and is being used in California for irrigation after minimal treatment. In this study, we identified chemicals that are used for hydraulic fracturing in California and conducted an analysis to determine if those chemicals would be removed by a variety of technically available treatment processes, including oil/water separation, air stripping, a variety of sorption media, advanced oxidation, biological treatment, and a variety of membrane treatment systems. The approach taken was to establish major physiochemical properties for individual chemicals (log Koc, Henry's constant, biodegradability, etc.), group chemicals by function (e.g corrosion inhibition, biocides), and use those properties to predict the fate of chemical additives in a treatment process. Results from this analysis is interpreted in the context of what is known about existing systems for the treatment of produced water before beneficial reuse, which includes a range of treatment systems from oil/water separators (the most common treatment) to sophisticated treatment trains used for purifying produced water for groundwater recharge. The results show that most HyF chemical additives will not be removed in existing treatment systems, but that more sophisticated treatment trains can be designed to remove additives before beneficial reuse.

  3. Requirements Elicitation in a Telemedicine Pain-treatment Trial

    NARCIS (Netherlands)

    Widya, I.A.; Bults, Richard G.A.; van Beijnum, Bernhard J.F.; Sandsjö, L.; Schaake, L.; Huis in 't Veld, M.H.A.; Jones, Valerie M.; Hermens, Hermanus J.; Ryan, K.; Robinson, W.

    2009-01-01

    This paper presents the early phase requirements elicitation for a work-related neck-shoulder pain teletreatment trial and the assessment of those requirements in respect of their importance to the trial and the feasibility of the needed software adaptations of the telemedicine system within the

  4. [Atlas burst fracture (Jefferson fracture) requiring surgical treatment after conservative treatment--report of two cases].

    Science.gov (United States)

    Yamamoto, Hiromichi; Kurimoto, Masanori; Hayashi, Nakamasa; Ohmori, Tomoaki; Hirashima, Yutaka; Endo, Shunro

    2002-09-01

    Most cases of atlas burst fracture do not require surgical stabilization, because they can be successfully treated with external immobilization. The authors present two cases of atlas burst fracture in which surgical stabilization was required after external immobilization. The first patient was a 50-year-old male and the second patient was a 34-year-old male. Both presented with neck pain without neurological symptoms after a traffic accident. Neuroradiological examinations revealed atlas burst fracture in both patients. They were initially treated with conservative treatment; one with a rigid collar and the other with a halo vest. However, lateral offset of the atlas on the axis increased and atlanto-axial instability became evident three months later in both patients. They underwent upper cervical arthrodesis with satisfactory results. The authors review surgical indication and its timing in patients with atlas burst fracture.

  5. 40 CFR 141.403 - Treatment technique requirements for ground water systems.

    Science.gov (United States)

    2010-07-01

    ....403 Treatment technique requirements for ground water systems. (a) Ground water systems with significant deficiencies or source water fecal contamination. (1) The treatment technique requirements of this... requirements of this section. (3) When a significant deficiency is identified at a Subpart H public...

  6. Heat treatment of firewood : meeting the phytosanitary requirements

    Science.gov (United States)

    Xiping Wang; Richard Bergman; Brian K. Brashaw; Scott Myers; Marc Joyal

    2011-01-01

    The movement of firewood within emerald ash borer- (EAB-) infested states and into adjoining states has been a major contributor to the spread of EAB throughout the United States and Canada. In an effort to stop the further spread of EAB from infested areas and to facilitate interstate commerce, USDA Animal and Plant Health Inspection Service (APHIS) has required and...

  7. Complex rectal polyps: other treatment modalities required when offering a transanal endoscopic microsurgery service.

    LENUS (Irish Health Repository)

    Joyce, Myles R

    2011-09-01

    Complex rectal polyps may present a clinical challenge. The study aim was to assess different treatment modalities required in the management of patients referred for transanal endoscopic microsurgery.

  8. A Technology-based Model for Learning

    Directory of Open Access Journals (Sweden)

    Michael Williams

    2004-12-01

    Full Text Available The Math Emporium, opened in 1997, is an open 7000-squaremeter facility with 550+ workstations arranged in an array of widely spaced hexagonal "pods", designed to support group work at the same time maintaining an academic air. We operate it 24/7 with math support personnel in attendance 12 hours per day. Students have access to online course resources at all times, from anywhere. We have used this unique asset to transform traditional classroom-based courses into technology based learning programs that have no class meetings at all. The structure of the program is very different from the conventional one, having a new set of expectations and motivations. The results include: more effective students, substantial cost savings, economies of scale and scope and a stream-lined process for creating new on-line courses.

  9. Energy conservation technologies based on thermodynamic principles

    Energy Technology Data Exchange (ETDEWEB)

    Hirata, Masaru [Shibaura Institute of Technology of Technology, Tokyo (Japan)

    1996-12-31

    In order to reduce CO{sub 2} emission to prevent global warming, the most promising way for electric generation in the Northeast Asia is to introduce cogeneration and {open_quotes}repowering{close_quotes} technologies based on high temperature gas turbines fueled by natural gas. Especially the old type coal burning boiler-steam turbine plants should be retrofit by introducing gas turbines to become highly efficient combined cycle. Same technologies should be applied to the old garbage incineration plants and/or even to the nuclear power plants. The exhaust heat or steam should become much increased and it should be utilized as the process heat for industries or heat supply as the distinct heating or cooling for residential area. This paper introduces a brief survey of these new technologies.

  10. A Review of Technology-Based Youth and Family-Focused Interventions.

    Science.gov (United States)

    MacDonell, Kathleen Watson; Prinz, Ronald J

    2016-10-27

    In the past 10 years, mental and behavioral health has seen a proliferation of technology-based interventions in the form of online and other computer-delivered programs. This paper focuses on technology-based treatment and preventive interventions aimed at benefitting children and adolescents via either involving the parents and families, or only the youth. The review considered only technology-based interventions that had at least one published study with a randomized controlled trial design. Questions being addressed included: (1) What are the technology-based interventions in the mental/behavioral health area that have been systematically evaluated in published studies? (2) What are the common and unique characteristics of these interventions and their application with respect to sample characteristics, target problems, and technology characteristics (platforms, structures, elements, and communication formats)? and (3) Which intervention approaches and strategies have accrued the greatest evidence? The review identified 30 technology-based psychosocial interventions for children and families, 19 of which were parent or family-focused (32 studies) and 11 of which were youth-focused (in 13 studies). For the parent/family-focused interventions, greatest promise was found in those that addressed either youth behavioral problems or depressive/anxious symptoms, as well as more general bolstering of parenting efficacy. The youth-focused interventions showed some promise in reducing depressive/anxious symptoms. Advantages and disadvantages of the technology-based approaches were considered, and areas for future research and development were discussed.

  11. 38 CFR 4.29 - Ratings for service-connected disabilities requiring hospital treatment or observation.

    Science.gov (United States)

    2010-07-01

    ...-connected disabilities requiring hospital treatment or observation. 4.29 Section 4.29 Pensions, Bonuses, and... § 4.29 Ratings for service-connected disabilities requiring hospital treatment or observation. A total... observation at Department of Veterans Affairs expense for a service-connected disability for a period in...

  12. 12 CFR 204.136 - Treatment of trust overdrafts for reserve requirement reporting purposes.

    Science.gov (United States)

    2010-01-01

    ... requirement reporting purposes. 204.136 Section 204.136 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM RESERVE REQUIREMENTS OF DEPOSITORY INSTITUTIONS (REGULATION D) Interpretations § 204.136 Treatment of trust overdrafts for reserve requirement reporting purposes. (a)...

  13. 49 CFR 40.289 - Are employers required to provide SAP and treatment services to employees?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Are employers required to provide SAP and... Professionals and the Return-to-Duty Process § 40.289 Are employers required to provide SAP and treatment services to employees? (a) As an employer, you are not required to provide a SAP evaluation or any...

  14. Ground Water Monitoring Requirements for Hazardous Waste Treatment, Storage and Disposal Facilities

    Science.gov (United States)

    The groundwater monitoring requirements for hazardous waste treatment, storage and disposal facilities (TSDFs) are just one aspect of the Resource Conservation and Recovery Act (RCRA) hazardous waste management strategy for protecting human health and the

  15. Financial Assurance Requirements for Hazardous Waste Treatment, Storage and Disposal Facilities

    Science.gov (United States)

    The Resource Conservation and Recovery Act (RCRA) requires all treatment, storage and disposal facilities (TSDFs) to demonstrate that they will have the financial resources to properly close the facility

  16. Quantification of the energy required for the destruction of Balanus Amphitrite larva by ultrasonic treatment

    Digital Repository Service at National Institute of Oceanography (India)

    Seth, N.; Chakravarty, P.; Khandeparker, L.; Anil, A.C.; Pandit, A.B.

    organism. Since the power used and treatment time for disinfection are economically, and practically, the most important parameters, the energy required to pulverize the larvae into pieces less than equal to 30 mm was determined as a function...

  17. Technology-Based Classroom Assessments: Alternatives to Testing

    Science.gov (United States)

    Salend, Spencer J.

    2009-01-01

    Although many teachers are using new technologies to differentiate instruction and administer tests, educators are also employing a range of technology-based resources and strategies to implement a variety of classroom assessments as alternatives to standardized and teacher-made testing. Technology-based classroom assessments focus on the use of…

  18. Technology-Based Classroom Assessments: Alternatives to Testing

    Science.gov (United States)

    Salend, Spencer J.

    2009-01-01

    Although many teachers are using new technologies to differentiate instruction and administer tests, educators are also employing a range of technology-based resources and strategies to implement a variety of classroom assessments as alternatives to standardized and teacher-made testing. Technology-based classroom assessments focus on the use of…

  19. 42 CFR 483.354 - General requirements for psychiatric residential treatment facilities.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false General requirements for psychiatric residential treatment facilities. 483.354 Section 483.354 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION REQUIREMENTS FOR STATES AND LONG TERM CARE FACILITIES Condition...

  20. The technology base for agile manufacturing

    Science.gov (United States)

    Brost, R. C.; Strip, D. R.; Eicker, P. J.

    1993-01-01

    The effective use of information is a critical problem faced by manufacturing organizations that must respond quickly to market changes. As product runs become shorter, rapid and efficient development of product manufacturing facilities becomes crucial to commercial success. Effective information utilization is a key element to successfully meeting these requirements. This paper reviews opportunities for developing technical solutions to information utilization problems within a manufacturing enterprise and outlines a research agenda for solving these problems.

  1. SU-E-T-619: Planning 131I Thyroid Treatments for Patients Requiring Hemodialysis

    Energy Technology Data Exchange (ETDEWEB)

    Stroud, D [Kaiser Permanente, Los Angeles Ca, CA (United States)

    2015-06-15

    Purpose: Treatment of 131I thyroid cancer patients who also require regular hemodialysis (HD) treatments requires consideration of the administered activity and the HD schedule. In this work the red bone marrow is considered the dose limiting organ and the treatment plan optimized the HD schedule with the amount of radioactivity administered. Methods: The ‘Safe’ dose was considered to be 2 Gy (200 rad) to the red bone marrow.1 131Iodine doses of 50 mCi to 100 mCi were modeled and found to require a range of HD schedules. In order to achieve the safe dose to the red marrow, more aggressive HD schedules are required. 100 mCi required an aggressive HD treatment of every 24 hours for at least one week to achieve the ‘safe’ dose and an exposure appropriate for release from the hospital. A more normal schedule of HD beginning at 18 hours then every 48 hours allowed for up to 60 mCi administered dose allowed for a safe dose and expected release after less than one week.2In addition room was equipped with video cameras cameras for monitoring the patient and their vital signs from an adjacent room during HD. In this way the dialysis nurses were able to monitor the patient closely from an adjoining room. Results: Two HD patients were administered adjusted doses of about 50 mCi. The medical and nursing staff were exposed to no more than 4 mR for the entire treatment. The residual Iodine in the patient appeared to be normal after 4 to 6 days when the patient was released. Conclusion: With careful treatment planning 131Iodine treatments can be performed safely for patients needing HD and treatments appear to be as effective as those for patients with normal renal function.

  2. 40 CFR 63.1583 - What are the emission points and control requirements for an industrial POTW treatment plant?

    Science.gov (United States)

    2010-07-01

    ....1583 What are the emission points and control requirements for an industrial POTW treatment plant? (a) The emission points and control requirements for an existing industrial POTW treatment plant are... control requirements for an industrial POTW treatment plant? 63.1583 Section 63.1583 Protection...

  3. Technology-based suicide prevention: current applications and future directions.

    Science.gov (United States)

    Luxton, David D; June, Jennifer D; Kinn, Julie T

    2011-01-01

    This review reports on current and emerging technologies for suicide prevention. Technology-based programs discussed include interactive educational and social networking Web sites, e-mail outreach, and programs that use mobile devices and texting. We describe innovative applications such as virtual worlds, gaming, and text analysis that are currently being developed and applied to suicide prevention and outreach programs. We also discuss the benefits and limitations of technology-based applications and discuss future directions for their use.

  4. 19 CFR 10.248 - Additional requirements for preferential treatment of brassieres.

    Science.gov (United States)

    2010-04-01

    .... Andean Trade Promotion and Drug Eradication Act Apparel and Other Textile Articles Under the Andean Trade Promotion and Drug Eradication Act § 10.248 Additional requirements for preferential treatment of brassieres... United States means: (i) The price of the fabrics when last purchased, f.o.b. port of exportation, as...

  5. 40 CFR Appendix to Subpart G of... - Applicant Questionnaire for Modification of Secondary Treatment Requirements

    Science.gov (United States)

    2010-07-01

    ... Water Description 1. (L,S) Are you applying for a modification based on a discharge to the ocean or to a... in 40 CFR 125.58(z)? If yes, what are the pollution sources contributing to the stress? . 3. (L,S...(s) cause increased treatment requirements for public water supply(s) to meet local, State, and...

  6. Stochastic modeling to identify requirements for centralized monitoring of distributed wastewater treatment.

    Science.gov (United States)

    Hug, T; Maurer, M

    2012-01-01

    Distributed (decentralized) wastewater treatment can, in many situations, be a valuable alternative to a centralized sewer network and wastewater treatment plant. However, it is critical for its acceptance whether the same overall treatment performance can be achieved without on-site staff, and whether its performance can be measured. In this paper we argue and illustrate that the system performance depends not only on the design performance and reliability of the individual treatment units, but also significantly on the monitoring scheme, i.e. on the reliability of the process information. For this purpose, we present a simple model of a fleet of identical treatment units. Thereby, their performance depends on four stochastic variables: the reliability of the treatment unit, the respond time for the repair of failed units, the reliability of on-line sensors, and the frequency of routine inspections. The simulated scenarios show a significant difference between the true performance and the observations by the sensors and inspections. The results also illustrate the trade-off between investing in reactor and sensor technology and in human interventions in order to achieve a certain target performance. Modeling can quantify such effects and thereby support the identification of requirements for the centralized monitoring of distributed treatment units. The model approach is generic and can be extended and applied to various distributed wastewater treatment technologies and contexts.

  7. Ozonation for source treatment of pharmaceuticals in hospital wastewater - ozone lifetime and required ozone dose

    DEFF Research Database (Denmark)

    Hansen, Kamilla Marie Speht; Spiliotopoulou, Aikaterini; Chhetri, Ravi Kumar

    2016-01-01

    Ozonation aimed at removing pharmaceuticals was studied in an effluent from an experimental pilot system using staged moving bed biofilm reactor (MBBR) tanks for the optimal biological treatment of wastewater from a medical care unit of Aarhus University Hospital. Dissolved organic carbon (DOC......) and pH in samples varied considerably, and the effect of these two parameters on ozone lifetime and the efficiency of ozone in removing pharmaceuticals were determined. The pH in the effluent varied from 5.0 to 9.0 resulting in approximately a doubling of the required ozone dose at the highest p......H for each pharmaceutical. DOC varied from 6 to 20 mg-DOC/L. The ozone required for removing each pharmaceutical, varied linearly with DOC and thus, ozone doses normalized to DOC (specific ozone dose) agreed between water samples (typically within 15%). At neutral pH the specific ozone dose required...

  8. Vega library for processing DICOM data required in Monte Carlo verification of radiotherapy treatment plans

    CERN Document Server

    Locke, C

    2008-01-01

    Monte Carlo (MC) method provides the most accurate to-date dose calculations in heterogeneous media and complex geometries, and this spawns increasing interest in incorporating MC calculations to treatment planning quality assurance process. This process involves MC dose calculations for the treatment plans produced clinically. To perform these calculations a number of treatment plan parameters specifying radiation beam and patient geometries needs to be transferred to MC codes such as BEAMnrc and DOSXYZnrc. Extracting these parameters from DICOM files is not a trivial task that has previously been performed mostly using Matlab-based software. This paper describes DICOM tags that contain information required for MC modeling of conformal and IMRT plans, and reports development of an in-house DICOM interface through a library (named Vega) of platform-independent, object-oriented C++ codes. Vega library is small and succinct, offering just the fundamental functions for reading/modifying/writing DICOM files in a ...

  9. Framework, process and tool for managing technology-based assets

    CSIR Research Space (South Africa)

    Kfir, R

    2000-10-01

    Full Text Available ) and the intellectual property (IP) of the organisation, The study describes a framework linking the core processes supporting the management of technology-based assets and offerings with other organisational elements such as leadership, strategy, and culture. Specific...

  10. FY02 Engineering Technology Reports Volume 1: Technology Base

    Energy Technology Data Exchange (ETDEWEB)

    Minichino, C; Meeker, D

    2003-01-28

    Engineering has touched on every challenge, every accomplishment, and every endeavor of Lawrence Livermore National Laboratory during its fifty-year history. In this time of transition to new leadership, Engineering continues to be central to the mission of the Laboratory, returning to the tradition and core values of E. O. Lawrence: science-based engineering--turning scientific concepts into reality. This volume of Engineering Technical Reports summarizes progress on the projects funded for technology-base efforts. Technology-base projects effect the natural transition to reduction-to-practice of scientific or engineering methods that are well understood and established. They represent discipline-oriented, core competency activities that are multi-programmatic in application, nature, and scope. Objectives of technology-base funding include: (1) the development and enhancement of tools and processes to provide Engineering support capability, such as code maintenance and improved fabrication methods; (2) the support of Engineering science and technology infrastructure, such as the installation or integration of a new capability; (3) support for technical and administrative leadership through our technology Centers; and (4) the initial scoping and exploration of selected technology areas with high strategic potential, such as assessment of university, laboratory, and industrial partnerships. Five Centers focus and guide longer-term investments within Engineering. The Centers attract and retain top staff, develop and maintain critical core technologies, and enable programs. Through their technology-base projects, they oversee the application of known engineering approaches and techniques to scientific and technical problems.

  11. STATUS KESEHATAN GIGI, PERFORMED TREATMENT INDEX DAN REQUIRED TREATMENT INDEX ANAK SEKOLAH DASAR DI KABUPATEN CIANJUR, KARAWANG DAN SERANG

    Directory of Open Access Journals (Sweden)

    Magdarina D. Agtini

    2012-10-01

    Full Text Available Community dental health status for permanent teeth in determined by the DMF-T (Decayed Misssing and Filled Teeth. The DMF-T in a number of industrialized nations shows a tendency to drop while the trend in developing nations is increasing. In Indonesia dental caries is still the foremost problem in oral and dental diseases, Prevalence of dental caries is around 85%-99%. The DMF-T is varied, reflect geographic and ages variations. In three decade's the intensity of dental caries is increasing with each decade, 0,70 DMF-T in 1970 to be 2,30 DMF-T in 1980 and 2,70 DMF-Tin 1990. Goal of dental caries control for 2010 is DMF-T ≤ 1 for 12 years age group. Baseline study is therefore necessary to ascertain DMF-T, PTI (Performed Treatment Index and RTI (Required Treatment Index. The study was implemented in the districts of Cianjur, Karawang and Serang in West Java for two years. The study design was cohort. The respondents  were 1200 pupils aged 8 years, randomly selected with a signifzcantcy grade of p < 0,05 and power of 0,20. The study results showed average of DMF-T at the beginning was 1,52 ± 1,21, and after two years the DMF-T was 2.45 ± 1.51 comprise only of the decayed component, and There was significant different (p=0,000. The DMF-T was low WHO criteria, nevertheless the PTI (1,2% was very low and the RTI (98% was very high. The DMF_T average shows a tendency to increase, with D as the largest component and F (Filling the smallest one. The control of dental caries faces several problems, like the limited number of manpower and facilities, and limited supply of water and electricity incertain areas. Therefore treatment of dental caries with GIC fillings using the ART method should be taken into consideration receive the necessary attention.   Key words:  Status kesehatan gigi, Karies, Performed treatment Index (PTI,  Required Treatment  Index (RTI

  12. Temperature and Time Requirements for Controlling Bed Bugs (Cimex lectularius under Commercial Heat Treatment Conditions

    Directory of Open Access Journals (Sweden)

    Stephen A. Kells

    2011-08-01

    Full Text Available Developing effective alternative approaches for disinfesting bed bugs from residential spaces requires a balance between obtaining complete insect mortality, while minimizing costs and energy consumption. One method of disinfestation is the application of lethal high temperatures directly to rooms and contents within a structure (termed whole-room heat treatments. However, temperature and time parameters for efficacy in whole-room heat treatments are unknown given the slower rate of temperature increase and the probable variability of end-point temperatures within a treated room. The objective of these experiments was to explore requirements to produce maximum mortality from heat exposure using conditions that are more characteristic of whole-room heat treatments. Bed bugs were exposed in an acute lethal temperature (LTemp trial, or time trials at sub-acute lethal temperatures (LTime. The lethal temperature (LTemp99 for adults was 48.3 °C, while LTemp99 for eggs was 54.8 °C. Adult bed bugs exposed to 45 °C had a LTime99 of 94.8 min, while eggs survived 7 h at 45 °C and only 71.5 min at 48 °C. We discuss differences in exposure methodologies, potential reasons why bed bugs can withstand higher temperatures and future directions for research.

  13. Temperature and Time Requirements for Controlling Bed Bugs (Cimex lectularius) under Commercial Heat Treatment Conditions.

    Science.gov (United States)

    Kells, Stephen A; Goblirsch, Michael J

    2011-08-29

    Developing effective alternative approaches for disinfesting bed bugs from residential spaces requires a balance between obtaining complete insect mortality, while minimizing costs and energy consumption. One method of disinfestation is the application of lethal high temperatures directly to rooms and contents within a structure (termed whole-room heat treatments). However, temperature and time parameters for efficacy in whole-room heat treatments are unknown given the slower rate of temperature increase and the probable variability of end-point temperatures within a treated room. The objective of these experiments was to explore requirements to produce maximum mortality from heat exposure using conditions that are more characteristic of whole-room heat treatments. Bed bugs were exposed in an acute lethal temperature (LTemp) trial, or time trials at sub-acute lethal temperatures (LTime). The lethal temperature (LTemp99) for adults was 48.3 °C, while LTemp99 for eggs was 54.8 °C. Adult bed bugs exposed to 45 °C had a LTime99 of 94.8 min, while eggs survived 7 h at 45 °C and only 71.5 min at 48 °C. We discuss differences in exposure methodologies, potential reasons why bed bugs can withstand higher temperatures and future directions for research.

  14. Build-up material requirements in clinical dosimetry during total body irradiation treatments.

    Science.gov (United States)

    Butson, Martin; Pope, Dane; Haque, Mamoon; Chen, Tom; Song, Guangli; Whitaker, May

    2016-01-01

    Total body irradiation (TBI) treatments are mainly used in a preparative regimen for hematopoietic stem cell (or bone marrow) transplantation. Our standard clinical regimen is a 12 Gy/6 fraction bi-daily technique using 6MV X-rays at a large extended source to surface distance (SSD). This work investigates and quantifies the dose build-up characteristics and thus the requirements for bolus used for in vivo dosimetry for TBI applications. Percentage dose build-up characteristics of photon beams have been investigated at large extended SSDs using ionization chambers and Gafchromic film. Open field measurements at different field sizes and with differing scatter conditions such as the introduction of standard Perspex scattering plates at different distances to the measurement point were made in an effort to determine the required bolus/build-up material required for accurate determination of applied dose. Percentage surface dose values measured for open fields at 300 cm SSD were found to range from 20% up to 65.5% for fields 5 cm × 5 cm to 40 cm × 40 cm, respectively. With the introduction of 1 cm Perspex scattering plates used in TBI treatments, the surface dose values increased up to 83-90% (93-97% at 1 mm depth), depending on the position of the Perspex scattering plate compared to the measurement point. Our work showed that at least 5 mm water equivalent bolus/scatter material should be placed over the EBT3 film for accurate dose assessment for TBI treatments. Results also show that a small but measurable decrease in measured dose occurred with 5 mm water equivalent thick bolus material of areas '3 cm(2). As such, we recommend that 3 cm × 3 cm × 5 mm bolus build-up is the smallest size that should be placed over EBT3 Gafchromic film when used for accurate in vivo dosimetry for TBI applications.

  15. Management of Forgotten Ureteral Stents: Relationship Between Indwelling Time and Required Treatment Approaches.

    Science.gov (United States)

    Polat, Hacı; Yücel, Mehmet Özgür; Utangaç, Mehmet M; Benlioğlu, Can; Gök, Alper; Çift, Ali; Kalyenci, Bedreddin; Lök, Uğur; Gülaçtı, Umut

    2017-08-04

    Double-J stents are widely used in urology practice, and removal of these stents can sometimes be forgotten. To investigate whether indwelling time of double-J stent can predict which treatment modality is required for removal of the stent from the body. A multicentre, retrospective observational study. The data of 57 patients who were treated for forgotten ureteral stents between January 2007 and December 2014 were evaluated retrospectively. Patients were classified into four groups according to indwelling time of the stents: 6-12 months, 13-24 months, 25-36 months, and forgotten double-J stents. Transurethral procedures are sufficient for the treatment of patients with double-J stent indwelling times less than 30 months.

  16. Do all hemolytic anemias that occur after mitral valve repair require surgical treatment?

    Science.gov (United States)

    Gungunes, Askin; Akpinar, Ibrahim; Dogan, Mehmet; Baser, Kazim; Yildirim, Ismail Safa; Haznedaroglu, Ibrahim C

    2010-12-01

    We report on a 29-year-old woman with severe hemolytic anemia following mitral valve annuloplasty. Although hemolysis due to mechanical prosthetic mitral valve is well recognized, hemolytic anemia associated with mitral valve repair is an uncommon condition. Reoperation may be considered if the patient has serious and persistent anemia. Although valve replacement is suggested to be a unique intervention, it may not be the solution every time because of mechanical effects. Various mechanisms of hemolysis related to mitral valve repair were suggested, but sufficient and precise data is not available. In this case, we tried to emphasize whether all hemolytic anemias that occur after mitral valve repair require surgical treatment.

  17. Dynamic managerial capability of technology-based international new ventures

    DEFF Research Database (Denmark)

    Altshuler, Liliya

    2014-01-01

    case study of a technology-based INV conducted over the period of 3.5 years, starting 8 years into the firm’s history. This unique design has enabled close observation of the specific events and challenges the firm has been facing after its initial success, and of the aspects in the firm’s management......The article focuses on long-term development of technology-based international new ventures (INVs) and discusses aspects of managing such ventures once they are past the initial success and rapid internationalization and enter the stable development phase. The study builds on an in-depth process...... to resource availability. The study takes the dynamic capability perspective and focuses on INVs’ management, which are seen as founders and builders of the processes, rules and structures that lay the basis for long-term competitive advantage for such firms. Based on the findings, specific aspects...

  18. Assistive Technology Based on Robotics and Rise in China

    Institute of Scientific and Technical Information of China (English)

    ZHANG Xiaoyu; WANG Kaixuan

    2013-01-01

    The concept of assistive technology based on robotics,rehabilitation robot and intelligent assistive devices.Domestic intelligence assistive devices include intelligent prosthetics,intelligent orthotics,intelligent walker,assistive devices for smart home environment control,intelligent life assistive devices; Domestic intelligent rehabilitation robot include upper limb rehabilitation robot,hand rehabilitation robot,lower limb rehabilitation robot,robotic smart wheelchair,intelligent nursing bed,daily care robot,the development trend of intelligent assistive devices and rehabilitation robot.

  19. Comparison of time required for traditional versus virtual orthognathic surgery treatment planning.

    Science.gov (United States)

    Wrzosek, M K; Peacock, Z S; Laviv, A; Goldwaser, B R; Ortiz, R; Resnick, C M; Troulis, M J; Kaban, L B

    2016-09-01

    Virtual surgical planning (VSP) is a tool for predicting complex surgical movements in three dimensions and it may reduce preoperative laboratory time. A prospective study to compare the time required for standard preoperative planning versus VSP was conducted at Massachusetts General Hospital from January 2014 through January 2015. Workflow data for bimaxillary cases planned by both standard techniques and VSP were recorded in real time. Time spent was divided into three parts: (1) obtaining impressions, face-bow mounting, and model preparation; (2) occlusal analysis and modification, model surgery, and splint fabrication; (3) online VSP session. Average times were compared between standard treatment planning (sum of parts 1 and 2) and VSP (sum of parts 1 and 3). Of 41 bimaxillary cases included, 20 were simple (symmetric) and 21 were complex (asymmetry and segmental osteotomies). Average times for parts 1, 2, and 3 were 4.43, 3.01, and 0.67h, respectively. The average time required for standard treatment planning was 7.45h and for VSP was 5.10h, a 31% time reduction (Porthognathic surgery cases.

  20. Engineering Technology Reports, Volume 2: Technology Base FY01

    Energy Technology Data Exchange (ETDEWEB)

    Minichino, C; Meeker, D

    2002-07-01

    Engineering has touched on every challenge, every accomplishment, and every endeavor of Lawrence Livermore National Laboratory during its fifty-year history. In this time of transition to new leadership, Engineering continues to be central to the mission of the Laboratory, returning to the tradition and core values of E.O. Lawrence: science-based engineering--turning scientific concepts into reality. This volume of Engineering Technical Reports summarizes progress on the projects funded for technology-base efforts. Technology-base projects effect the natural transition to reduction-to-practice of scientific or engineering methods that are well understood and established. They represent discipline-oriented, core competency activities that are multi-programmatic in application, nature, and scope. Objectives of technology-base funding include: (1) the development and enhancement of tools and processes to provide Engineering support capability, such as code maintenance and improved fabrication methods; (2) the support of Engineering science and technology infrastructure, such as the installation or integration of a new capability; (3) support for technical and administrative leadership through our technology Centers; (4) the initial scoping and exploration of selected technology areas with high strategic potential, such as assessment of university, laboratory, and industrial partnerships.

  1. Pain in the cancer patient: different pain characteristics CHANGE pharmacological treatment requirements.

    Science.gov (United States)

    Müller-Schwefe, Gerhard; Ahlbeck, Karsten; Aldington, Dominic; Alon, Eli; Coaccioli, Stefano; Coluzzi, Flaminia; Huygen, Frank; Jaksch, Wolfgang; Kalso, Eija; Kocot-Kępska, Magdalena; Kress, Hans-Georg; Mangas, Ana Cristina; Ferri, Cesar Margarit; Morlion, Bart; Nicolaou, Andrew; Hernández, Concepción Pérez; Pergolizzi, Joseph; Schäfer, Michael; Sichère, Patrick

    2014-09-01

    Twenty years ago, the main barriers to successful cancer pain management were poor assessment by physicians, and patients' reluctance to report pain and take opioids. Those barriers are almost exactly the same today. Cancer pain remains under-treated; in Europe, almost three-quarters of cancer patients experience pain, and almost a quarter of those with moderate to severe pain do not receive any analgesic medication. Yet it has been suggested that pain management could be improved simply by ensuring that every consultation includes the patient's rating of pain, that the physician pays attention to this rating, and a plan is agreed to increase analgesia when it is inadequate. After outlining current concepts of carcinogenesis in some detail, this paper describes different methods of classifying and diagnosing cancer pain and the extent of current under-treatment. Key points are made regarding cancer pain management. Firstly, the pain may be caused by multiple different mechanisms and therapy should reflect those underlying mechanisms - rather than being simply based on pain intensity as recommended by the WHO three-step ladder. Secondly, a multidisciplinary approach is required which combines both pharmacological and non-pharmacological treatment, such as psychotherapy, exercise therapy and electrostimulation. The choice of analgesic agent and its route of administration are considered, along with various interventional procedures and the requirements of palliative care. Special attention is paid to the treatment of breakthrough pain (particularly with fast-acting fentanyl formulations, which have pharmacokinetic profiles that closely match those of breakthrough pain episodes) and chemotherapy-induced neuropathic pain, which affects around one third of patients who receive chemotherapy. Finally, the point is made that medical education should place a greater emphasis on pain therapy, both at undergraduate and postgraduate level.

  2. Onychomycosis does not always require systemic treatment for cure: a trial using topical therapy.

    Science.gov (United States)

    Friedlander, Shiela Fallon; Chan, Yuin C; Chan, Yiong H; Eichenfield, Lawrence F

    2013-01-01

    Standard teaching dictates that systemic therapy is required for treatment of onychomycosis. It is unknown whether topical antifungal therapy is effective for pediatric nail infections. This prospective, randomized, double-blind, vehicle-controlled study was conducted in the Pediatric Dermatology Research Unit at Rady Children's Hospital to determine whether topical antifungal therapy is efficacious for pediatric onychomycosis. Forty patients ages 2 to 16 years with nonmatrix onychomycosis were randomized 1:3 to ciclopirox lacquer or vehicle lacquer. Ciclopirox lacquer or vehicle was applied daily for 32 weeks, with weekly removal of the lacquer and mechanical trimming. Those with poor response were crossed over to active drug at week 12. Thirty-seven patients completed the 32-week study, and follow-up data were collected 1 year after completion of the study from 24 patients. Mycologic cure, effective treatment, and complete cure were assessed, as well as adverse events and effect on quality of life. Mycologic cure was 70% in the treated group and 20% in the vehicle arm (p = 0.03) at week 12. At end of the study (week 32), 77% of treated patients achieved mycologic cure and 71% effective treatment, compared with 22% of the control group. Ninety-two percent of those who were cured and followed for 1 year remained clear. Topical antifungal lacquer (ciclopirox) can be an effective option for children with nonmatrix onychomycosis. Pediatric onychomycosis does not always require systemic therapy and responds better to topical therapy than does adult disease.

  3. Wastewater treatment models in teaching and training: the mismatch between education and requirements for jobs.

    Science.gov (United States)

    Hug, Thomas; Benedetti, Lorenzo; Hall, Eric R; Johnson, Bruce R; Morgenroth, Eberhard; Nopens, Ingmar; Rieger, Leiv; Shaw, Andrew; Vanrolleghem, Peter A

    2009-01-01

    As mathematical modeling of wastewater treatment plants has become more common in research and consultancy, a mismatch between education and requirements for model-related jobs has developed. There seems to be a shortage of skilled people, both in terms of quantity and in quality. In order to address this problem, this paper provides a framework to outline different types of model-related jobs, assess the required skills for these jobs and characterize different types of education that modelers obtain "in school" as well as "on the job". It is important to consider that education of modelers does not mainly happen in university courses and that the variety of model related jobs goes far beyond use for process design by consulting companies. To resolve the mismatch, the current connection between requirements for different jobs and the various types of education has to be assessed for different geographical regions and professional environments. This allows the evaluation and improvement of important educational paths, considering quality assurance and future developments. Moreover, conclusions from a workshop involving practitioners and academics from North America and Europe are presented. The participants stressed the importance of non-technical skills and recommended strengthening the role of realistic modeling experience in university training. However, this paper suggests that all providers of modeling education and support, not only universities, but also software suppliers, professional associations and companies performing modeling tasks are called to assess and strengthen their role in training and support of professional modelers.

  4. Comparison of technology-based cooperative learning with technology-based individual learning in enhancing fundamental nursing proficiency.

    Science.gov (United States)

    Lin, Zu-Chun

    2013-05-01

    The aim of nursing education is to prepare students with critical thinking, high interests in profession and high proficiency in patient care. Cooperative learning promotes team work and encourages knowledge building upon discussion. It has been viewed as one of the most powerful learning methods. Technology has been considered an influential tool in teaching and learning. It assists students in gathering more information to solve the problems and master skills better. The purpose of this study was to compare the effect of technology-based cooperative learning with technology-based individual learning in nursing students' critical thinking in catheterization knowledge gaining, error discovering, skill acquisitions, and overall scores. This study used a pretest-posttest experimental design. Ninety-eight students were assigned randomly to one of two groups. Questionnaires and tests were collected at baseline and after completion of intervention. The results of this study showed that there was no significant difference in related catheterization skill performance. However, the remaining variables differed greatly between the two groups. CONCLUSIONS AND APPLICATIONS: This study's findings guide the researchers and instructors to use technology-based cooperative learning more appropriately. Future research should address the design of the course module and the availability of mobile devices to reach student-centered and learn on the move goals. Copyright © 2011 Elsevier Ltd. All rights reserved.

  5. [Wisdom teeth-complications requiring in-patient treatment. A 1-year prospective study].

    Science.gov (United States)

    Kunkel, Martin; Morbach, Thomas; Wagner, Wilfried

    2004-11-01

    In view of the conflicting guidelines issued by national and international scientific societies, debate about the indications for prophylactic extraction of wisdom teeth is ongoing. This prospective study was therefore set up to explore the complications associated with wisdom teeth and requiring in-patient treatment. From January /2003 to December 2003, 21 subjects were admitted for treatment of complications associated with wisdom teeth. The medical history was recorded for each of these patients, as were the cause and type of the complications. The parameter used to quantify the severity of any infections was the CRP, and the overall clinical complexity level of each case was assessed by the length of stay in hospital (and the duration of intensive care if this had been necessary). The characteristics of patients in the group with postoperative complications were compared to those of patients with complications attributable to pericoronitis. Moreover, complications in patients who had undergone prophylactic extraction of wisdom teeth that had not been causing any symptoms were compared with those in patients whose wisdom teeth had been extracted because of morbidity. Overall, 18 deep-space infections (15 abscesses, 2 inflammatory infiltrations, 1 case of phlegmonous cellulitis), 2 mandibular fractures and 1 lingual nerve injury were noted within 1 year. The complications resulted from surgical procedures in 15 of the 21 cases, while in 6 they had their origin in pericoronitis. Extensive surgery or intensive care was required only for patients with postoperative complications. The length of stay in hospital was significantly greater for patients with postoperative complications ( p= 0.007, U-test). However, 9 of these 15 patients reported preoperative episodes of infection. Thus, more than two thirds of the complications could be traced back to wisdom teeth that were causing symptoms. In our clinic's catchment area, infectious complications were more frequent and

  6. EVALUATION OF SUPPLEMENTAL PRE-TREATMENT DEVELOPMENT REQUIREMENTS TO MEET TRL 6 ROTARY MICROFILTRATION

    Energy Technology Data Exchange (ETDEWEB)

    HUBER HJ

    2011-10-03

    In spring 2011, the Technology Maturation Plan (TMP) for the Supplemental Treatment Project (RPP-PLAN-49827, Rev. 0), Technology Maturation Plan for the Treatment Project (T4S01) was developed. This plan contains all identified actions required to reach technical maturity for a field-deployable waste feed pretreatment system. The supplemental pretreatment system has a filtration and a Cs-removal component. Subsequent to issuance of the TMP, rotary microfiltration (RMF) has been identified as the prime filtration technology for this application. The prime Cs-removal technology is small column ion exchange (ScIX) using spherical resorcinol formaldehyde (sRF) as the exchange resin. During fiscal year 2011 (FY2011) some of the tasks identified in the TMP have been completed. As of September 2011, the conceptual design package has been submitted to DOE as part of the critical decision (CD-1) process. This document describes the remaining tasks identified in the TMP to reach technical maturity and evaluates the validity of the proposed tests to fill the gaps as previously identified in the TMP. The potential vulnerabilities are presented and the completed list of criteria for the DOE guide DOE G 413.3-4 different technology readiness levels are added in an attachment. This evaluation has been conducted from a technology development perspective - all programmatic and manufacturing aspects were excluded from this exercise. Compliance with the DOE G 413.3-4 programmatic and manufacturing requirements will be addressed directly by the Treatment Project during the course of engineering design. The results of this evaluation show that completion of the proposed development tasks in the TMP are sufficient to reach TRL 6 from a technological point of view. The tasks involve actual waste tests using the current baseline configuration (2nd generation disks, 40 psi differential pressure, 30 C feed temperature) and three different simulants - the PEP, an AP-Farm and an S

  7. Participatory Research as One Piece of the Puzzle: A Systematic Review of Consumer Involvement in Design of Technology-Based Youth Mental Health and Well-Being Interventions

    OpenAIRE

    Orlowski, Simone; Lawn, Sharon; Venning, Anthony; Winsall, Megan; Jones, Gabrielle M; Wyld, Kaisha; Damarell, Raechel A; Antezana, Gaston; Schrader, Geoffrey; Smith, David; Collin, Philippa; Bidargaddi, Niranjan

    2015-01-01

    Background Despite the potential of technology-based mental health interventions for young people, limited uptake and/or adherence is a significant challenge. It is thought that involving young people in the development and delivery of services designed for them leads to better engagement. Further research is required to understand the role of participatory approaches in design of technology-based mental health and well-being interventions for youth. Objective To investigate consumer involvem...

  8. Comparing credentialing requirements of substance abuse treatment staff by funding source.

    Science.gov (United States)

    Kubiak, Sheryl Pimlott; Arfken, Cynthia L

    2008-07-01

    Studies have found that clinicians with higher education and/or attainment of national certification have a more favorable outlook regarding the adoption of evidence-based practices. However, staff hiring decisions may be based on a multitude of factors, including available resources and demands stemming from different funders. Using a mixed-methods case study approach with 34 agencies within one state, we assessed administrators' perspectives of the most important funding source, views on clinical hiring practices, and current staffing. We found that funding source predicted views and actual staff level of credentialing and education. Those agencies citing a criminal justice entity as the most important funder had the lowest requirements for credentialing and education. As the substance abuse treatment delivery system evolves and expands, we must ensure that vulnerable groups have access to more highly--rather than less--skilled workers to assess and facilitate recovery.

  9. Risk Factors for the Requirement of Antenatal Insulin Treatment in Gestational Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Mayu Watanabe

    2016-01-01

    Full Text Available Poor maternal glycemic control increases maternal and fetal risk for adverse outcomes, and strict management of gestational diabetes mellitus (GDM is recommended to prevent neonatal and maternal complications. However, risk factors for the requirement of antenatal insulin treatment (AIT are not well-investigated in the pregnant women with GDM. We enrolled 37 pregnant women with GDM and investigated the risk for AIT by comparing the patients with AIT (AIT group; n=10 and without insulin therapy (Diet group; n=27. The 1-h and 2-h plasma glucose levels and the number of abnormal values in 75 g OGTT were significantly higher in AIT group compared with Diet group. By logistic regression analysis, plasma glucose level at 1-h was significant predictor for AIT and the odds ratios were 1.115 (1.004–1.239 using forward selection method and 1.192 (1.006–1.413 using backward elimination method. There were no significant differences in obstetrical outcomes and neonatal complications. 1-h plasma glucose levels in 75 g OGTT are useful parameters in predicting the requirement for AIT in GDM. Both maternal and neonatal complications are comparable in GDM patients with and without insulin therapy.

  10. Structural model requirements to describe microbial inactivation during a mild heat treatment.

    Science.gov (United States)

    Geeraerd, A H; Herremans, C H; Van Impe, J F

    2000-09-10

    The classical concept of D and z values, established for sterilisation processes, is unable to deal with the typical non-loglinear behaviour of survivor curves occurring during the mild heat treatment of sous vide or cook-chill food products. Structural model requirements are formulated, eliminating immediately some candidate model types. Promising modelling approaches are thoroughly analysed and, if applicable, adapted to the specific needs: two models developed by Casolari (1988), the inactivation model of Sapru et al. (1992), the model of Whiting (1993), the Baranyi and Roberts growth model (1994), the model of Chiruta et al. (1997), the model of Daughtry et al. (1997) and the model of Xiong et al. (1999). A range of experimental data of Bacillus cereus, Yersinia enterocolitica, Escherichia coli O157:H7, Listeria monocytogenes and Lactobacillus sake are used to illustrate the different models' performances. Moreover, a novel modelling approach is developed, fulfilling all formulated structural model requirements, and based on a careful analysis of literature knowledge of the shoulder and tailing phenomenon. Although a thorough insight in the occurrence of shoulders and tails is still lacking from a biochemical point of view, this newly developed model incorporates the possibility of a straightforward interpretation within this framework.

  11. Analysis of diplopia associated with thyroid-associated ophthalmopathy requiring surgical treatment

    Energy Technology Data Exchange (ETDEWEB)

    Funaki, Chika; Yamazaki, Sei; Maeda, Toshine; Inoue, Yoichi [Olympia Eye Hospital, Tokyo (Japan)

    2003-03-01

    The purpose of this study was to analyze diplopia associated with thyroid-associated ophthalmopathy requiring surgical treatment. Five hundred patients operated upon for diplopia by a single surgeon were included in this study. Stretching of extraocular muscles was evaluated by orbital magnetic resonance imaging (MRI) or computed tomography (CT). Ocular motility was evaluated in 9 positions of gaze using the Hess chart and field of fixation and duction test. Surgical treatment for diplopia was placement of an adjustable suture. Two hundred-twenty-four patients were male (mean age 53.9 years) and 276 patients were female (mean age 52.1 years). Three hundred-seventy patients (70%) had unilateral ocular motility dysfunction and 130 patients had bilateral dysfunction. In patients with unilateral dysfunction, the frequency of each direction of gaze dysfunction was as follows: upward gaze, 63.2%; outward, 6.8%; downward, 16.5%; inward, 0.8%; and complex, 12.7%. In patients with bilateral dysfunction, the frequency of each direction of gaze dysfunction was as follows: 11.5%, 41.5%, 5.4%, 0%, and 41.5% respectively. The majority of patients in this study had unilateral ocular motility. The most frequent direction of gaze restriction was upward in those with unilateral diplopia and outward and complex in those with bilateral diplopia. Stretching of the lateral or medial rectus muscle alone occurred very rarely in this population. (author)

  12. Recruitment and ethical considerations in HIV cure trials requiring treatment interruption.

    Science.gov (United States)

    Arnold, Michael P; Evans, David; Vergel, Nelson

    2015-01-01

    Relative to antiretroviral treatment (ART), early HIV cure-related trials (HCRTs) carry limited therapeutic benefits and unknown risks. In HCRTs requiring treatment interruption (TI) the health risks and burdens may create a barrier to study enrolment and increase the possibility for unintentional ethical violations in recruitment. An online survey was administered to over 2,000 HIV-positive ART users in the US. Using multivariable ordinal regression we assessed effects of research participation attitudes, health and demographic traits on willingness to participate in treatment interruption studies (WtP-TI). WtP-TI was greatest among those who were highly motivated to participate in research studies for the benefit of science, society and, to a lesser extent, personal benefit. Personal benefit was less of an influence on WtP-TI among persons with higher viral loads or a history of multiple ART regimens. WtP-TI was greater among respondents who were more likely to consider personal health in making decisions about trial participation. WtP-TI had no association with perceptions of the importance of compensation to research participation. After accounting for attitudes, health status and demographic traits were generally not significantly related to WtP-TI. Notable exceptions included viral suppression status and race/ethnicity. Recruitment strategies in TI studies can benefit from a focus on the long-term scientific and social benefits of study participation. Strategies targeted to particular demographic groups may have little impact on accrual, and in some cases will need to be accompanied by strategies to improve the quality of researcher-community relationships. Findings also suggest that informing communities about the health impacts of trial participation may positively impact participation decisions. However, more research is needed to interpret the impact of health messaging on recruitment and therapeutic expectations. Future work should explore the

  13. Innovative cold joining technologies based on tube forming

    Directory of Open Access Journals (Sweden)

    Alves Luis M.

    2015-01-01

    Full Text Available This paper is focused on innovative cold joining technologies for connecting tubes and fixing tubes to sheets. The proposed technologies are based on the utilization of plastic instability waves in thin-walled tubes subjected to axial compression and may be seen as an alternative to conventional joining technologies based on mechanical fixing with fasteners, welding and structural adhesive bonding. Besides allowing connecting dissimilar materials and being successfully employed in fixture conditions that are difficult and costly to achieve by means of conventional joining the new proposed technologies also cope with the growing concerns on the demand, lifecycle and recycling of materials.

  14. Antifungal Treatment is Not Required for Immunocompetent Individuals With Asymptomatic Esophageal Candidiasis.

    Science.gov (United States)

    Min, Yang Won; Kim, Eun; Son, Hee Jung; Kim, Jae J; Rhee, Poong-Lyul

    2015-11-01

    Although esophageal candidiasis (EC) is an opportunistic infection, asymptomatic EC (AEC) is occasionally encountered in otherwise healthy individuals. This study evaluates the impact of antifungal treatment in immunocompetent individuals with AEC and investigates risk factors for persistent or recurrent EC. The authors identified patients with biopsy-proven AEC from the database of individuals receiving screening endoscopy (n = 99,255). After excluding patients receiving immunosuppressive therapy, being positive for human immunodeficiency virus, receiving no follow-up endoscopy, or having no antifungal treatment data, a total of 142 patients were divided into remission and nonremission groups. Remission was defined when EC was not detectable on follow-up endoscopy. On baseline comparison, nonremission group was older (57.5 ± 10.3 versus 52.5 ± 10.5 years, P = 0.017) and more likely to have cardiovascular disease (12.9% versus 1.8%, P = 0.021) and history of pulmonary tuberculosis (PTB) (22.6% versus 4.5%, P = 0.004) and exhibited a lower triglyceride level (101.4 ± 37.4 versus 122.6 ± 79.6 mg/dL, P = 0.039) than remission group, whereas grade of EC and concomitant endoscopic findings did not differ between 2 groups. Antifungal treatment was also similarly performed between 2 groups. Multivariate analysis revealed that history of PTB is independently associated with nonremission (odds ratio 4.495, 95% confidence interval 1.023-19.762, P = 0.047). No patients demonstrated EC-related complications during a mean follow-up of 28.0 ± 12.0 months. In conclusion, our results suggested that antifungal treatment is not required for immunocompetent individuals with AEC and past history of PTB is an independent predictor for persistent or recurrent EC.

  15. 20 CFR 416.1725 - Effect of your failure to comply with treatment requirements for your drug addiction or alcoholism.

    Science.gov (United States)

    2010-04-01

    ... treatment requirements for your drug addiction or alcoholism. 416.1725 Section 416.1725 Employees' Benefits... Persons Eligible for Supplemental Security Income to Other Agencies Referral for Treatment of Alcoholism... drug addiction or alcoholism. (a) Suspension of benefits. Your eligibility for benefits will...

  16. From the Accounting Treatment Required by the Accounting Regulations Corresponding with European Directives to the Accounting Treatment Required by IFRS - Legislative Steps Taken by Romanian Credit Institutions

    OpenAIRE

    Doroº Alexandra

    2013-01-01

    Legislative stages in accordance with IFRS accounting treatment began to OMF no. 907/2005- approving categories of entities applying accounting rules in accordance with International Financial Reporting Standards, accounting regulations that comply with European directives, as amended, continued with NBR Order no. 13/2008, NBR Order no. 15/2009, NBR Order no. 9/2010 and ends with NBR Order No. 27/16.12.2010 - for approval of Accounting Regulations in accordance with International Financial Re...

  17. PHARMACOECONOMIC ASPECTS OF NICOTINE ADDICTION TREATMENT IN PATIENTS WITH ANGINA REQUIRING CARDIAC SURGERY

    Directory of Open Access Journals (Sweden)

    A. V. Rudakova

    2012-01-01

    Full Text Available Smoking is a major risk factor in patients with angina pectoris. Interventions that facilitate the rejection of it are an important part of the treatment. Aim. To analyze the cost effectiveness of the partial agonist of nicotinic receptors, varenicline, in patients with angina who require cardiac interventions. Material and methods. The estimation was conducted using a Markov model based on the results of clinical trials and epidemiological studies. The cost of treatment of complications were calculated on the basis of compulsory medical insurance rates for St. Petersburg in 2011. Results. The varenicline therapy in 70-year-old patients before cardiac surgery reduces hospital mortality at an extremely high cost-effectiveness (the cost of preventing one death - 148.8 thousand rubles. The cost/effectiveness ratio in the analysis for the period of survival of patients in this situation was 31.3 thousand rubles for 1 additional year of life. Life expectancy will be increased by an average of 0.147 years. Analysis for the period of survival of 50-year-old patients has shown that in patients after cardiac surgery cost-effectiveness of varenicline is extremely high (in the analysis from the perspective of the health care system the cost/effectiveness ratio was 36.0 thousand rubles for 1 additional year of life, in the analysis, taking into account the social perspective – 17.9 thousand rubles for 1 additional year of life. Increase in the life expectancy of 50 year-old patients will be 0.291 year in average. Conclusion. Varenicline therapy of patients with angina pectoris is the economy before cardiac surgery , and after their execution, and this applies not only young, but older patients. The desirability of varenicline including to federal and regional programs to reduce cardiovascular morbidity and mortality is shown.

  18. PHARMACOECONOMIC ASPECTS OF NICOTINE ADDICTION TREATMENT IN PATIENTS WITH ANGINA REQUIRING CARDIAC SURGERY

    Directory of Open Access Journals (Sweden)

    A. V. Rudakova

    2015-12-01

    Full Text Available Smoking is a major risk factor in patients with angina pectoris. Interventions that facilitate the rejection of it are an important part of the treatment. Aim. To analyze the cost effectiveness of the partial agonist of nicotinic receptors, varenicline, in patients with angina who require cardiac interventions. Material and methods. The estimation was conducted using a Markov model based on the results of clinical trials and epidemiological studies. The cost of treatment of complications were calculated on the basis of compulsory medical insurance rates for St. Petersburg in 2011. Results. The varenicline therapy in 70-year-old patients before cardiac surgery reduces hospital mortality at an extremely high cost-effectiveness (the cost of preventing one death - 148.8 thousand rubles. The cost/effectiveness ratio in the analysis for the period of survival of patients in this situation was 31.3 thousand rubles for 1 additional year of life. Life expectancy will be increased by an average of 0.147 years. Analysis for the period of survival of 50-year-old patients has shown that in patients after cardiac surgery cost-effectiveness of varenicline is extremely high (in the analysis from the perspective of the health care system the cost/effectiveness ratio was 36.0 thousand rubles for 1 additional year of life, in the analysis, taking into account the social perspective – 17.9 thousand rubles for 1 additional year of life. Increase in the life expectancy of 50 year-old patients will be 0.291 year in average. Conclusion. Varenicline therapy of patients with angina pectoris is the economy before cardiac surgery , and after their execution, and this applies not only young, but older patients. The desirability of varenicline including to federal and regional programs to reduce cardiovascular morbidity and mortality is shown.

  19. Prospects of Applying Feed Processing Technologies Based on Industrial Plantation

    Directory of Open Access Journals (Sweden)

    Simon Petrus Ginting

    2012-06-01

    Full Text Available The potency of plantation sectors (palm oil, sugar cane and cacao as alternative feed resources for ruminants has been acknowledged since 20 – 25 years ago. However, the level of utilization of these feeds in small ruminant production system has been very low and sporadic. The typical chemical and physical characteristics of most of those feedstuffs required some steps of processing in order to improve their nutritional quality and to ease their handling. Small ruminants, like sheep and goats have relatively higher metabolic energy requirement per kg BW and anatomically have lower gut capacity to process lignocelluose materials compared to large ruminants. It is, therefore, these animals nutritionally face more constraints in handling lignocellulose and bulky materials mostly found in industrial by products or crop-residues from plantations. Physical processes (chopping, phyiscal separation, hydrothermal, chemical processes (ammoniation, hydrolyses and oxidative treatments and bio-conversions (fermentation, ensiling have been recommended as alternative technologies in maximizing the utilization of those feedstuffs for small ruminant animals. The principal mechanisms of those treatments are: (i breaking the linkages between structural carbohydrate and lignin so that it could be easily digested by the animal enzyme systems and (ii preserving the material from being spoilage due to its high moisture content or for feed stocking purposes. Priorities for choosing the most effective processing technology for implementation or adoption is depent largely on the scale of feed production. Ammoniation, chopping, physical separation, ensiling or bio-conversion are several technologies mostly recommended for small scale operation in situ. These alternative technologies should be able to be adopted by small-holders living around the plantation area. The commercial or large scale feed production could be implemented by the plantation industry by giving high

  20. The Alliance Capability of Technology-Based Born Globals

    DEFF Research Database (Denmark)

    Oxtorp, Liliya Altshuler; Elg, Ulf

    2015-01-01

    A detailed investigation of the aspects comprising the alliance capability of technology-based born globals. Alliance capability is regarded as a set of organizational skills necessary from the decision to search for a partner for a technology collaboration, which may also involve a marketing...... organisational skills that enable the firms to successfully initiate, manage and finish their R&D alliances with MNEs. The in-depth longitudinal methodology adds insight and value to the study. It is discussed how the specific aspects of the alliance capability can help born globals to counteract the challenges...... and risks of collaborating with MNEs.Methodology: A longitudinal process study of a Danish technology born global with three embedded cases of its R&D and marketing alliances with Asian MNEs.Findings: The organisational skills comprising the alliance capability are defined to be internal and external...

  1. The Alliance Capability of Technology-Based Born Globals

    DEFF Research Database (Denmark)

    Oxtorp, Liliya Altshuler; Elg, Ulf

    2015-01-01

    A detailed investigation of the aspects comprising the alliance capability of technology-based born globals. Alliance capability is regarded as a set of organizational skills necessary from the decision to search for a partner for a technology collaboration, which may also involve a marketing...... aspect, through initiation and management of the alliance, up until its objectives are achieved, or otherwise. Originality/value of paper: While earlier research discussed networking and alliance strategies of born globals on a strategic level, this paper investigates and analyses the specific...... and risks of collaborating with MNEs.Methodology: A longitudinal process study of a Danish technology born global with three embedded cases of its R&D and marketing alliances with Asian MNEs.Findings: The organisational skills comprising the alliance capability are defined to be internal and external...

  2. Image Restoration Technology Based on Discrete Neural network

    Directory of Open Access Journals (Sweden)

    Zhou Duoying

    2015-01-01

    Full Text Available With the development of computer science and technology, the development of artificial intelligence advances rapidly in the field of image restoration. Based on the MATLAB platform, this paper constructs a kind of image restoration technology of artificial intelligence based on the discrete neural network and feedforward network, and carries out simulation and contrast of the restoration process by the use of the bionic algorithm. Through the application of simulation restoration technology, this paper verifies that the discrete neural network has a good convergence and identification capability in the image restoration technology with a better effect than that of the feedforward network. The restoration technology based on the discrete neural network can provide a reliable mathematical model for this field.

  3. Competitive intelligence information management and innovation in small technology-based companies

    Science.gov (United States)

    Tanev, Stoyan

    2007-05-01

    In this article we examine how (i) company type and (ii) the competitive intelligence information used by small technology-based companies affect their innovation performance. The focus is on the specific information types used and not on the information sources. Information topics are classified in four groups - customers (10), company (9), competitor (11) and industry (12). The sample consists of 45 small new technology-based companies, specialized suppliers, and service companies from a variety of sectors - software, photonics, telecommunications, biomedical engineering and biotech, traditional manufacturing etc. The results suggest that the total number of intelligence information topics companies use to make decisions about innovation is not associated with the number of their new products, processes, services and patents. Therefore the companies in our sample do not seem to have the resources, processes or value systems required to use different competitive intelligence information when making decisions on innovation or may rely more on their own internal logic than on external information. Companies are classified using a Pavitt-like taxonomy. Service companies are considered as a separate company type. This allows for explicitly studying both, the innovative role of new services in product driven companies, and the role of new product development in service companies.

  4. 77 FR 39959 - Draft Guidance To Implement Requirements for the Treatment of Air Quality Monitoring Data...

    Science.gov (United States)

    2012-07-06

    ... Air Quality Monitoring Data Influenced by Exceptional Events AGENCY: Environmental Protection Agency... for the Treatment of Air Quality Monitoring Data Influenced by Exceptional Events and associated... Treatment of Air Quality Monitoring Data Influenced by Exceptional Events and associated attachments and...

  5. Emerging Implications of Balancing Disinfection and Primary Treatment as an Element in CSO Control: Model Requirements

    Science.gov (United States)

    This paper describes early results and directions arising from ongoing research into factors that affect the preferred balance between primary treatment and disinfection in a conventional wastewater treatment plant during periods of wet weather overflow. Despite the fact that na...

  6. 40 CFR 141.82 - Description of corrosion control treatment requirements.

    Science.gov (United States)

    2010-07-01

    ... corrosion control treatment for that system: (i) Alkalinity and pH adjustment; (ii) Calcium hardness... evaluating the corrosion control treatments listed above: (i) Lead; (ii) Copper; (iii) pH; (iv) Alkalinity... alkalinity is adjusted as part of optimal corrosion control treatment, a minimum concentration or a range...

  7. 40 CFR 63.1586 - What are the emission points and control requirements for a non-industrial POTW treatment plant?

    Science.gov (United States)

    2010-07-01

    ... are the emission points and control requirements for a non-industrial POTW treatment plant? There are no control requirements for an existing non-industrial POTW treatment plant. There are no control... control requirements for a non-industrial POTW treatment plant? 63.1586 Section 63.1586 Protection...

  8. Expectation requires treatment to boost pain relief: an fMRI study.

    Science.gov (United States)

    Schenk, Lieven A; Sprenger, Christian; Geuter, Stephan; Büchel, Christian

    2014-01-01

    We investigated the effect of a possible interaction between topical analgesic treatment and treatment expectation on pain at the behavioral and neuronal level by combining topical lidocaine/prilocaine treatment with an expectancy manipulation in a 2 by 2 within-subject design (open treatment, hidden treatment, placebo, control). Thirty-two healthy subjects received heat pain stimuli on capsaicin-pretreated skin and rated their experienced pain during functional magnetic resonance imaging. This allowed us to separate drug- and expectancy-related effects at the behavioral and neuronal levels and to test whether they interact during the processing of painful stimuli. Pain ratings were reduced during active treatment and were associated with reduced activity in the anterior insular cortex. Pain ratings were lower in open treatment compared with hidden treatment and were related to reduced activity in the anterior insular cortex, the anterior cingulate cortex, the secondary somatosensory cortex, and the thalamus. Testing for an interaction revealed that the expectation effect was significantly larger in the active treatment conditions compared with the no-treatment conditions and was associated with signal changes in the anterior insular cortex, the anterior cingulate cortex, and the ventral striatum. In conclusion, this study shows that even in the case of a topical analgesic, expectation interacts with treatment at the level of pain ratings and neuronal responses in placebo-related brain regions. Our results are highly relevant in the clinical context as they show (i) that expectation can boost treatment and (ii) that expectation and treatment are not necessarily additive as assumed in placebo-controlled clinical trials.

  9. GUIDELESS SPATIAL COORDINATE MEASUREMENT TECHNOLOGY BASED ON CODING POLE

    Institute of Scientific and Technical Information of China (English)

    ZHAO Min; QIU Zongming; QU Jiamin; LIU Hongzhao

    2008-01-01

    A new method of guideless spatial coordinate measurement technology based on coding pole and vision measurement is proposed. Unequal spacing of bar code is adopted to pole, so that the code combination of pole image in measuring field is unique. Holographic characteristics of numeric coding pole are adopted to obtain pole pose and pole probe position by any section of bar code on the pole. Spatial coordinates of measuring points can be obtained by coordinate transform. The contradiction between high resolution and large visual field of image sensor is resolved, thereby providing a new concept for surface shape measurement of large objects with high precision. The measurement principles of the system are expounded and mathematic model is established. The measurement equation is evaluated by simulation experiments and the measurement precision is analyzed. Theoretical analysis and simulation experiments prove that this system is characterized by simple structure and wide measurement range. Therefore it can be used in the 3-dimentional coordinate measurement of large objects.

  10. Reliability analysis for new technology-based transmitters

    Energy Technology Data Exchange (ETDEWEB)

    Brissaud, Florent, E-mail: florent.brissaud.2007@utt.f [Institut National de l' Environnement Industriel et des Risques (INERIS), Parc Technologique Alata, BP 2, 60550 Verneuil-en-Halatte (France); Universite de Technologie de Troyes (UTT), Institut Charles Delaunay (ICD) and STMR UMR CNRS 6279, 12 rue Marie Curie, BP 2060, 10010 Troyes cedex (France); Barros, Anne; Berenguer, Christophe [Universite de Technologie de Troyes (UTT), Institut Charles Delaunay (ICD) and STMR UMR CNRS 6279, 12 rue Marie Curie, BP 2060, 10010 Troyes cedex (France); Charpentier, Dominique [Institut National de l' Environnement Industriel et des Risques (INERIS), Parc Technologique Alata, BP 2, 60550 Verneuil-en-Halatte (France)

    2011-02-15

    The reliability analysis of new technology-based transmitters has to deal with specific issues: various interactions between both material elements and functions, undefined behaviours under faulty conditions, several transmitted data, and little reliability feedback. To handle these particularities, a '3-step' model is proposed, based on goal tree-success tree (GTST) approaches to represent both the functional and material aspects, and includes the faults and failures as a third part for supporting reliability analyses. The behavioural aspects are provided by relationship matrices, also denoted master logic diagrams (MLD), with stochastic values which represent direct relationships between system elements. Relationship analyses are then proposed to assess the effect of any fault or failure on any material element or function. Taking these relationships into account, the probabilities of malfunction and failure modes are evaluated according to time. Furthermore, uncertainty analyses tend to show that even if the input data and system behaviour are not well known, these previous results can be obtained in a relatively precise way. An illustration is provided by a case study on an infrared gas transmitter. These properties make the proposed model and corresponding reliability analyses especially suitable for intelligent transmitters (or 'smart sensors').

  11. Required duration of mass ivermectin treatment for onchocerciasis elimination in Africa: a comparative modelling analysis

    NARCIS (Netherlands)

    W.A. Stolk (Wilma); M. Walker (Martin); L.E. Coffeng (Luc); M-G. Basáñez (María-Gloria); S.J. de Vlas (Sake)

    2015-01-01

    textabstractBackground: The World Health Organization (WHO) has set ambitious targets for the elimination of onchocerciasis by 2020-2025 through mass ivermectin treatment. Two different mathematical models have assessed the feasibility of reaching this goal for different settings and treatment scena

  12. 7 CFR 319.37-6 - Specific treatment and other requirements.

    Science.gov (United States)

    2010-01-01

    ..., Hong Kong, India, Indonesia, Ivory Coast, Japan, Kampuchea, Korea, Madagascar, Malaysia, Mauritius... owner and the plant protection service of the exporting country, in which the treatment facility owner... plant protection service of the exporting country access to the treatment facility as necessary to...

  13. 20 CFR 416.936 - Treatment required for individuals whose drug addiction or alcoholism is a contributing factor...

    Science.gov (United States)

    2010-04-01

    ... addiction or alcoholism is a contributing factor material to the determination of disability. 416.936... AGED, BLIND, AND DISABLED Determining Disability and Blindness Drug Addiction and Alcoholism § 416.936 Treatment required for individuals whose drug addiction or alcoholism is a contributing factor material...

  14. 20 CFR 404.1536 - Treatment required for individuals whose drug addiction or alcoholism is a contributing factor...

    Science.gov (United States)

    2010-04-01

    ... addiction or alcoholism is a contributing factor material to the determination of disability. 404.1536... Treatment required for individuals whose drug addiction or alcoholism is a contributing factor material to... alcoholism is a contributing factor material to the determination of disability (as described in §...

  15. Adjunctive treatment of decompression illness with a non-steroidal anti-inflammatory drug (tenoxicam) reduces compression requirement.

    Science.gov (United States)

    Bennett, M; Mitchell, S; Dominguez, A

    2003-01-01

    We report a randomized trial examining adjunctive administration of the NSAID, tenoxicam, to divers suffering with DCI. 180 subjects were graded for severity on admission and randomized according to a stratified random number schedule. Subjects were recompressed and treatment continued daily until symptom stabilization or complete resolution. Tenoxicam 20 mg or a placebo preparation was administered at the first air break during the initial recompression and continued daily for seven days. The subjects were assessed using a recovery status score at the completion of treatment and at 4-6 weeks. The proportion of patients with mild residual symptoms at discharge and final follow-up was not significantly different (discharge placebo 30% versus tenoxicam 37%, P=0.41; six weeks placebo 20% versus tenoxicam 17%, P=0.58). There was a significant reduction in the number of treatments required to achieve discharge (median treatments placebo 3, tenoxicam 2, P=0.01). 61% of patients in the tenoxicam group required less than 3 compressions, versus 40% in the placebo group (P=0.01, RRR 33 % [95%CI 9%-56%], NNT=5 [95%CI 3-18]). There was no evidence of increased complications of treatment in the tenoxicam group. When given this NSAID, patients with DCI require fewer hyperbaric oxygen (HBO2) sessions to achieve a standard clinical end-point and there is likely to be an associated cost saving.

  16. Guideline-adherent inpatient psychiatric psychotherapeutic treatment of borderline personality disorder. Normative definition of personnel requirements

    OpenAIRE

    Bohus, M.; Schmahl, C.; Herpertz, S. C.; Lieb, K.; Berger, M.; Roepke, S.; Heinz, A; Gallinat, J.; Lyssenko, L.

    2016-01-01

    Abstract: Background. Borderline personality disorders (BPD) are severe mental diseases which place high pressure on the psychiatric healthcare system. Nowadays, well-tested, disorder-specific treatment concepts are available also for inpatient treatment in Germany. These show very good and long-term improvements in the psychopathology as well as posttreatment social participation; however, prerequisites for the implementation of these evidence-based inpatient psychotherapy programs are well-...

  17. Quantitative and qualitative characteristics of grey water for reuse requirements and treatment alternatives: the case of Jordan.

    Science.gov (United States)

    Ghunmi, Lina Abu; Zeeman, Grietje; van Lier, Jules; Fayyed, Manar

    2008-01-01

    The objective of this work is to assess the potentials and requirements for grey water reuse in Jordan. The results revealed that urban, rural and dormitory grey water production rate and concentration of TS, BOD(5), COD and pathogens varied between 18-66 L cap(-1)d(-1), 848-1,919, 200-1,056, and 560-2,568 mg L(-1) and 6.9E2-2.7E5 CFU mL(-1), respectively. The grey water compromises 64 to 85% of the total water flow in the rural and urban areas. Storing grey water is inevitable to meet reuse requirements in terms of volume and timing. All the studied grey waters need treatment, in terms of solids, BOD(5), COD and pathogens, before storage and reuse. Storage and physical treatment, as a pretreatment step should be avoided, since it produces unstable effluents and non-stabilized sludge. However, extensive biological treatment can combine storage and physical treatments. Furthermore, a batch-fed biological treatment system combining anaerobic and aerobic processes copes with the fluctuations in the hydrographs and pollutographs as well as the present nutrients. The inorganic content of grey water in Jordan is about drinking water quality and does not need treatment. Moreover, the grey water SAR values were 3-7, revealing that the concentrations of monovalent and divalent cations comply with agricultural demand in Jordan. The observed patterns in the hydrographs and pollutographs showed that the hydraulic load could be used for the design of both physical and biological treatment units for dormitories and hotels. For family houses the hydraulic load was identified as the key design parameter for physical treatment units and the organic load is the key design parameter for biological treatment units.

  18. Understandings of the nature of science and decision making on science and technology-based issues

    Science.gov (United States)

    Bell, Randy Lee

    Current reforms emphasize the development of scientific literacy as the principal goal of science education. The nature of science is considered a critical component of scientific literacy and is assumed to be an important factor in decision making on science and technology based issues. However, little research exists that delineates the role of the nature of science in decision making. The purpose of this investigation was to explicate the role of the nature of science in decision making on science and technology based issues and to delineate the reasoning and factors associated with these types of decisions. The 15-item, open-ended "Decision Making Questionnaire" (DMQ) based on four different scenarios concerning science and technology issues was developed to assess decision making. Twenty-one volunteer participants purposively selected from the faculty of geographically diverse universities completed the questionnaire and follow-up interviews. Participants were subsequently grouped according to their understandings of the nature of science, based on responses to a second open-ended questionnaire and follow-up interview. Profiles of each group's decision making were constructed, based on their previous responses to the DMQ and follow-up interviews. Finally, the two groups' decisions, decision making factors, and decision making strategies were compared. No differences were found between the decisions of the two groups, despite their disparate views of the nature of science. While their reasoning did not follow formal lines of argumentation, several influencing factors and general reasoning patterns were identified. Participants in both groups based their decisions primarily on personal values, morals/ethics, and social concerns. While all participants said they considered scientific evidence in their decision making, most did not require absolute "proof," even though Group B participants held more absolute conceptions of the nature of science. Overall, the

  19. Treatment Burden and Treatment Fatigue as Barriers to Health

    Science.gov (United States)

    Heckman, Bryan W.; Mathew, Amanda R.; Carpenter, Matthew J.

    2015-01-01

    Effective management of chronic diseases involves sustained changes in health behavior, which often requires substantial effort and patient burden. As treatment burden is associated with reduced adherence across several chronic conditions, its assessment and treatment are important clinical priorities. The balance between patient demands and capacity (e.g., coping resources) may be indexed by patients’ subjective experience of treatment fatigue. We present a modified workload-capacity model that incorporates evidence that treatment fatigue may 1) be caused by increased workload due to treatment burden (e.g., intensity, complications) and 2) undermine adherence. Emerging technology-based interventions may be well-suited to reduce treatment burden, prevent treatment fatigue, and increase treatment adherence. PMID:26086031

  20. Treatment of confirmed B12 deficiency in hemodialysis patients improves Epogen® requirements

    Directory of Open Access Journals (Sweden)

    Saifan C

    2013-06-01

    Full Text Available Chadi Saifan, Mark Samarneh, Norbert Shtaynberg, Rabih Nasr, Elie El-Charabaty, Suzanne El-Sayegh Division of Nephrology, Staten Island University Hospital, Staten Island, NY, USA Background: Vitamin B12 deficiency may have deleterious effects on end stage renal disease (ESRD patients on maintenance hemodialysis, and may increase erythropoietin stimulating agent (ESA resistance, yet little is known about its prevalence in this population. Methods: Serum Vitamin B12 and methylmalonic acid (MMA levels were drawn from ESRD patients prior to hemodialysis. All patients with MMA levels greater than 800 nmol/L had peripheral smears evaluated for B12 deficiency. Those with confirmatory smears were considered to be deficient and received intramuscular vitamin B12 injections for 4 months. Post-treatment MMA levels and smears were obtained. Erythropoietin dosages were monitored throughout the treatment period. Results: There was a 58% (60/103 prevalence of vitamin B12 deficiency as defined by a positive MMA level and a positive blood smear. Out of 52 patients with positive smears, 36 (69.2% were negative on repeat analysis after B12 treatment. Mean Epogen® (EPO dosages significantly decreased by 16,572 ± 41,902 units per month from baseline to the post-B12 treatment period (P = 0.0082, Wilcoxon signed-rank test. Three months prior to treatment, the mean monthly EPO dose was 82,067 ± 47,906 and post, the mean EPO usage was 65,495 ± 39,691. Post treatment hemoglobin levels were not significantly different from baseline. Conclusion: Vitamin B12 supplementation was associated with a decrease in the mean dose of ESA administration while maintaining a stable hemoglobin level. Maintaining serum vitamin B12 levels improves functionality, and may allow a decrease in the use of ESA’s, avoiding their toxicities and significant costs. Keywords: ESRD, end stage renal disease, chronic kidney disease, anemia, vitamin deficiency, erythropoietin, dialysis

  1. Restrictive Behaviour Management Procedures with People with Intellectual Disabilities Who Require Dental Treatment

    Science.gov (United States)

    Newton, J. T.

    2009-01-01

    Background: Dental disease is more common among people with intellectual disabilities than in the general population. Improvements in oral health require individuals to engage in daily oral hygiene and regular visits to a dental practitioner; both may be challenging for the individual with intellectual impairment. Materials and Methods: A review…

  2. Restrictive Behaviour Management Procedures with People with Intellectual Disabilities Who Require Dental Treatment

    Science.gov (United States)

    Newton, J. T.

    2009-01-01

    Background: Dental disease is more common among people with intellectual disabilities than in the general population. Improvements in oral health require individuals to engage in daily oral hygiene and regular visits to a dental practitioner; both may be challenging for the individual with intellectual impairment. Materials and Methods: A review…

  3. 40 CFR Table 12 to Subpart G of... - Monitoring Requirements for Treatment Processes

    Science.gov (United States)

    2010-07-01

    ... and/or Table 9 compound(s) from wastewater treated in a properly operated biological treatment unit... Chemical Manufacturing Industry for Process Vents, Storage Vessels, Transfer Operations, and Wastewater Pt... recorder. (ii) Wastewater feed mass flow rate; and Continuously Liquid flow meter installed at...

  4. Successful treatment of Batrachochytrium salamandrivorans infections in salamanders requires synergy between voriconazole, polymyxin E and temperature.

    Science.gov (United States)

    Blooi, M; Pasmans, F; Rouffaer, L; Haesebrouck, F; Vercammen, F; Martel, A

    2015-06-30

    Chytridiomycosis caused by the chytrid fungus Batrachochytrium salamandrivorans (Bsal) poses a serious threat to urodelan diversity worldwide. Antimycotic treatment of this disease using protocols developed for the related fungus Batrachochytrium dendrobatidis (Bd), results in therapeutic failure. Here, we reveal that this therapeutic failure is partly due to different minimum inhibitory concentrations (MICs) of antimycotics against Bsal and Bd. In vitro growth inhibition of Bsal occurs after exposure to voriconazole, polymyxin E, itraconazole and terbinafine but not to florfenicol. Synergistic effects between polymyxin E and voriconazole or itraconazole significantly decreased the combined MICs necessary to inhibit Bsal growth. Topical treatment of infected fire salamanders (Salamandra salamandra), with voriconazole or itraconazole alone (12.5 μg/ml and 0.6 μg/ml respectively) or in combination with polymyxin E (2000 IU/ml) at an ambient temperature of 15 °C during 10 days decreased fungal loads but did not clear Bsal infections. However, topical treatment of Bsal infected animals with a combination of polymyxin E (2000 IU/ml) and voriconazole (12.5 μg/ml) at an ambient temperature of 20 °C resulted in clearance of Bsal infections. This treatment protocol was validated in 12 fire salamanders infected with Bsal during a field outbreak and resulted in clearance of infection in all animals.

  5. Aggressive adolescents in residential care : A selective review of treatment requirements and models

    NARCIS (Netherlands)

    Knorth, Erik J.; Klomp, Martin; Van den Bergh, Peter M.; Noom, Marc J.

    2007-01-01

    This article presents a selective inventory of treatment methods of aggressive behavior. Special attention is paid to types of intervention that, according to research, are frequently used in Dutch residential youth care. These methods are based on (1) principles of (cognitive) behavior management a

  6. 40 CFR 141.715 - Microbial toolbox options for meeting Cryptosporidium treatment requirements.

    Science.gov (United States)

    2010-07-01

    ... Protection and Management Toolbox Options (1) Watershed control program 0.5-log credit for State-approved.../intake management No prescribed credit. Systems may conduct simultaneous monitoring for treatment bin... criteria are in § 141.717(b). (5) Bank filtration 0.5-log credit for 25-foot setback; 1.0-log credit for...

  7. Military Personnel: Enhanced Collaboration and Process Improvements Needed for Determining Military Treatment Facility Medical Personnel Requirements

    Science.gov (United States)

    2010-07-01

    dentists, medical service corps, and veterinarians , to name a few, at the work center level across Army fixed military treatment facilities. The model uses...1072 - 896 903 Hematology /Oncology 41 40 43 - 12 17 - 18 14 Infectious Disease 63 59 62 - 29 34 - 16 17 Internal Medicine 315 e 254 e 277 e

  8. Malocclusion and early orthodontic treatment requirements in the mixed dentitions of a population of Nigerian children

    Science.gov (United States)

    daCosta, Oluranti Olatokunbo; Aikins, Elfleda Angelina; Isiekwe, Gerald Ikenna; Adediran, Virginia Efunyemi

    2016-01-01

    Introduction: The aims of this study were to establish the prevalence of dental features that indicate a need for early intervention and to ascertain the prevalence of different methods of early treatment among a population of Nigerian children in mixed dentition. Methods: Occlusal relationships were evaluated in 101 children in mixed dentition between the ages of 6 and 12 years who presented at the Orthodontic Unit, Department of Child Dental Health, Lagos University Teaching Hospital over a 2 years period. The need for different modes of early orthodontic treatment was also recorded. Results: Anterior tooth rotations (61.4%) and increased overjet (44.6%) were the most prevalent occlusal anomalies. Others included deep bite (31.7%), reverse overjet (13.9%), and anterior open bite (14.8%). Severe maxillary spacing and crowding were exhibited in 12.0% and 5.0%, respectively. About a third (35.7%) of the subjects presented with crossbite while lip incompetence was observed in 43.6% of the subjects. About 44% of the subjects also presented with various oral habits with digit (15.8%) and lip sucking (9.9%) being the most prevalent. Subjects were recommended for treatment with 2 by 4 fixed orthodontic appliances (22.3%), habit breakers (20.7%), removable orthodontic appliances (16.5%), and extractions (15.7%). Conclusions: Increased overjet and anterior tooth rotation were the majority of occlusal anomalies seen, which are not only esthetically displeasing but may also cause an increased susceptibility to trauma to these teeth. Treatment options varied from extractions only to the use of appliance therapy. PMID:27556019

  9. Extreme thrombocytosis in admissions to paediatric intensive care: no requirement for treatment

    Science.gov (United States)

    Denton, Alison; Davis, Peter

    2007-01-01

    Extreme thrombocytosis (ExtThr; platelet count ⩾1000×109/l) is uncommon but may have an increased occurrence in critically ill children. The incidence of ExtThr for children on the Paediatric Intensive Care Unit at Bristol Royal Hospital for Children between January 2001 and December 2004 was calculated, and the notes of children identified with ExtThr were reviewed for possible common aetiological factors, potential treatment regimes and outcome. PMID:17515621

  10. METHODS FOR DETERMINING AGITATOR MIXING REQUIREMENTS FOR A MIXING & SAMPLING FACILITY TO FEED WTP (WASTE TREATMENT PLANT)

    Energy Technology Data Exchange (ETDEWEB)

    GRIFFIN PW

    2009-08-27

    The following report is a summary of work conducted to evaluate the ability of existing correlative techniques and alternative methods to accurately estimate impeller speed and power requirements for mechanical mixers proposed for use in a mixing and sampling facility (MSF). The proposed facility would accept high level waste sludges from Hanford double-shell tanks and feed uniformly mixed high level waste to the Waste Treatment Plant. Numerous methods are evaluated and discussed, and resulting recommendations provided.

  11. [Management of TB suspected cases of drug resistant tuberculosis requiring a second treatment].

    Science.gov (United States)

    Caminero, José A

    2004-06-01

    The management of patients with resistance to anti tuberculous drugs is complex and therefore must be managed by physician specialists. The most difficult patients are the cases in retreatment, where some very different possibilities are possible, as abandonment, failures and relapses. Patients with multi-drug resistant (MDR) tuberculosis are the most difficult to treat; MDR appears in all the failures or non-adherences to the treatment regime. To elaborate a scheme of retreatment for these patients, two guidelines must be followed: (1) do not rely on outcomes of drug susceptibility tests and (2) a detailed history of drug treatment must be considered of paramount importance. With this information, a retreatment scheme can be formulated that involves the use of at least three drugs not previously taken by the patient. For a successful control of tuberculosis, the national tuberculosis programs in Latin American countries must assure careful management of newly diagnosed patients. Secondly, if resources are available, a bank of second-line drugs must be ready for managing retreatment situations (e.g., 3 Z-Kn-Eth-Of/15 Z-Eth-Of) if first line drug treatments fail. Using individualized retreatment with second line drugs is recommended only in industrialized countries, and for a few middle income countries as a last resort.

  12. Transrectal high-intensity focused ultrasound ablation of prostate cancer: Effective treatment requiring accurate imaging

    Energy Technology Data Exchange (ETDEWEB)

    Rouviere, Olivier [Hospices Civils de Lyon, Department of Urinary and Vascular Radiology, Pavillon P Radio, Hopital Edouard Herriot, F-69437 Lyon cedex 03 (France); Universite de Lyon, Lyon F-69003 (France); Universite de Lyon 1, Faculte de Medecine Lyon Nord, Lyon F-69003 (France); INSERM, Unit 556, 151 cours Albert Thomas, F-69424 Lyon cedex 03 (France)], E-mail: Olivier.rouviere@netcourrier.com; Souchon, Remi [INSERM, Unit 556, 151 cours Albert Thomas, F-69424 Lyon cedex 03 (France)], E-mail: souchon@lyon.inserm.fr; Salomir, Rares [INSERM, Unit 556, 151 cours Albert Thomas, F-69424 Lyon cedex 03 (France)], E-mail: salomir@lyon.inserm.fr; Gelet, Albert [Hospices Civils de Lyon, Department of Urology, Pavillon P Radio, Hopital Edouard Herriot, F-69437 Lyon cedex 03 (France)], E-mail: Albert.gelet@chu-lyon.fr; Chapelon, Jean-Yves [INSERM, Unit 556, 151 cours Albert Thomas, F-69424 Lyon cedex 03 (France)], E-mail: chapelon@lyon.inserm.fr; Lyonnet, Denis [Hospices Civils de Lyon, Department of Urinary and Vascular Radiology, Pavillon P Radio, Hopital Edouard Herriot, F-69437 Lyon cedex 03 (France); Universite de Lyon, Lyon F-69003 (France); Universite de Lyon 1, Faculte de Medecine Lyon Nord, Lyon F-69003 (France); INSERM, Unit 556, 151 cours Albert Thomas, F-69424 Lyon cedex 03 (France)], E-mail: Denis.lyonnet@chu-lyon.fr

    2007-09-15

    Transrectal HIFU ablation has become a reasonable option for the treatment of localized prostate cancer in non-surgical patients, with 5-year disease-free survival similar to that of radiation therapy. It is also a promising salvage therapy of local recurrence after radiation therapy. These favourable results are partly due to recent improvements in prostate cancer imaging. However, further improvements are needed in patient selection, pre-operative localization of the tumor foci, assessment of the volume treated and early detection of recurrence. A better knowledge of the factors influencing the HIFU-induced tissue destruction and a better pre-operative assessment of them by imaging techniques should improve treatment outcome. Whereas prostate HIFU ablation is currently performed under transrectal ultrasound guidance, MR guidance with real-time operative monitoring of temperature will be available in the near future. If this technique will give better targeting and more uniform tissue destruction, its cost-effectiveness will have to be carefully evaluated. Finally, a recently reported synergistic effect between HIFU ablation and chemotherapy opens possibilities for treatment in high-risk or clinically advanced tumors.

  13. Multiculturalism in Technology-Based Education: Case Studies on ICT-Supported Approaches

    Science.gov (United States)

    Garcia-Penalvo, Francicso Jose

    2013-01-01

    Our differences in language, cultures, and history around the world play a vital role in the way we learn. As technology-based education continues to be used worldwide, there is an ever growing interest in how multiculturalism comes into effect. Multiculturalism in Technology-Based Education: Case Studies on ICT-Supported Approaches explores the…

  14. Demonstration of New Technologies Required for the Treatment of Mixed Waste Contaminated with {ge}260 ppm Mercury

    Energy Technology Data Exchange (ETDEWEB)

    Morris, M.I.

    2002-02-06

    The Resource Conservation and Recovery Act (RCRA) defines several categories of mercury wastes, each of which has a defined technology or concentration-based treatment standard, or universal treatment standard (UTS). RCRA defines mercury hazardous wastes as any waste that has a TCLP value for mercury of 0.2 mg/L or greater. Three of these categories, all nonwastewaters, fall within the scope of this report on new technologies to treat mercury-contaminated wastes: wastes as elemental mercury; hazardous wastes with less than 260 mg/kg [parts per million (ppm)] mercury; and hazardous wastes with 260 ppm or more of mercury. While this report deals specifically with the last category--hazardous wastes with 260 ppm or more of mercury--the other two categories will be discussed briefly so that the full range of mercury treatment challenges can be understood. The treatment methods for these three categories are as follows: Waste as elemental mercury--RCRA identifies amalgamation (AMLGM) as the treatment standard for radioactive elemental mercury. However, radioactive mercury condensates from retorting (RMERC) processes also require amalgamation. In addition, incineration (IMERC) and RMERC processes that produce residues with >260 ppm of radioactive mercury contamination and that fail the RCRA toxicity characteristic leaching procedure (TCLP) limit for mercury (0.20 mg/L) require RMERC, followed by AMLGM of the condensate. Waste with <260 ppm mercury--No specific treatment method is specified for hazardous wastes containing <260 ppm. However, RCRA regulations require that such wastes (other than RMERC residues) that exceed a TCLP mercury concentration of 0.20 mg/L be treated by a suitable method to meet the TCLP limit for mercury of 0.025 mg/L. RMERC residues must meet the TCLP value of {ge}0.20 mg/L, or be stabilized and meet the {ge}0.025 mg/L limit. Waste with {ge}260 ppm mercury--For hazardous wastes with mercury contaminant concentrations {ge}260 ppm and RCRA

  15. Computer and mobile technology-based interventions for substance use disorders: an organizing framework.

    Science.gov (United States)

    Litvin, Erika B; Abrantes, Ana M; Brown, Richard A

    2013-03-01

    Research devoted to the development of therapeutic, behavioral interventions for substance use disorders (SUDs) that can be accessed and delivered via computer and mobile technologies has increased rapidly during the past decade. Numerous recent reviews of this literature have supported the efficacy of technology-based interventions (TBIs), but have also revealed their great heterogeneity and a limited understanding of treatment mechanisms. We conducted a "review of reviews" focused on summarizing findings of previous reviews with respect to moderators of TBIs' efficacy, and present an organizing framework of considerations involved in designing and evaluating TBIs for SUDs. The four primary elements that comprise our framework are Accessibility, Usage, Human Contact, and Intervention Content, with several sub-elements within each category. We offer some suggested directions for future research grouped within these four primary considerations. We believe that technology affords unique opportunities to improve, support, and supplement therapeutic and peer relationships via dynamic applications that adapt to individuals' constantly changing motivation and treatment needs. We hope that our framework will aid in guiding programmatic progress in this exciting field.

  16. Study of 35 Cases of Hansen's Disease, which Required Treatment beyond Fixed Duration--Multi Drug Therapy.

    Science.gov (United States)

    Jethva, M V; Patel, R M; Marfatia, Y S

    2015-01-01

    Multi Drug Therapy (MDT) is the main weapon against leprosy since its inception in 1981. India achieved the level of elimination (disease activity after completion of treatment. Aims of the present study was to study the profile of RFT cases in leprosy treated with FD-MDT, who required extended MDT, duration between completion of FD -MDT and clinical presentation, Acid Fast Bacilli (AFB) status, histopathology and type of leprosy at the time of presentation. A prospective study of 35 RFT (Released FromTreatment) cases with signs of activity were recruited in period betveen May 2007 to November 2001. All cases were diagnosed clinically and investigations were done for AFB smear, histopathological examination and Fite Faraco staining. We found that all the 35 cases, which required extended MDT, age group ranged from 10 to 65 years. Majority (71.4%) had taken previous Multi-Bacillary (MB) treatment for 1 year duration. Eleven (31.42%) of cases came within one year, 17 (48.57%) between one to two years and 7 (20%) cases after two years of stopping FD-MDT. AFB smear was positive in 36.84% of cases in which done. Majority of previously diagnosed MB cases presented as BT/TT in histopathology. Thus there is need to search for reliable prognostic markers for therapeutic purposes.

  17. Impact of orthodontic treatment on self-esteem and quality of life of adult patients requiring oral rehabilitation.

    Science.gov (United States)

    de Couto Nascimento, Vanessa; de Castro Ferreira Conti, Ana Cláudia; de Almeida Cardoso, Maurício; Valarelli, Danilo Pinelli; de Almeida-Pedrin, Renata Rodrigues

    2016-09-01

    To evaluate whether orthodontic treatment in adults requiring oral rehabilitation is effective for increasing patients' self-esteem and quality of life (QoL). The sample consisted of 102 adult patients (77 women and 25 men) aged between 18 and 66 years (mean, 35.1 years) requiring oral rehabilitation and orthodontic treatment simultaneously. Rosenberg's Self-Esteem (RSE) Scale and a questionnaire about QoL based on the Oral Health Impact Profile (OHIP-14) were used to determine self-esteem and QoL scores retrospectively. Questionnaires were carried out in two stages, T1 (start of treatment) and T2 (6 months after). To compare score changes between T1 and T2, the data obtained from the RSE Scale were evaluated with paired t tests, and data from the quality-of-life questionnaire were assessed by applying descriptive statistics. The results showed a statistically significant increase in self-esteem (P self-esteem and QoL, providing psychological benefits for adult patients in need of oral rehabilitation.

  18. Estimated financial and human resources requirements for the treatment of malaria in Malawi

    Directory of Open Access Journals (Sweden)

    Rudatsikira Emmanuel

    2007-12-01

    Full Text Available Abstract Background Malaria fever is a common medical presentation and diagnosis in Malawi. The national malaria policy supports self-diagnosis and self-medication for uncomplicated malaria with first line anti-malaria drugs. While a qualitative appreciation of the burden of malaria on the health system is recognized, there is limited quantitative estimation of the burden malaria exacts on the health system, especially with regard to human resources and financial burden on Malawi. Methods The burden of malaria was assessed based on estimated incidence rates for a high endemic country of which Malawi is one. Data on the available human resources and financial resources committed towards malaria from official Malawi government documents and programme reports were obtained. The amount of human and financial resources that would be required to treat 65% or 85% of symptomatic malaria cases as per the Roll Back Malaria partnership and the US President's Malaria Initiative targets. Results Based on a malaria incidence rate of 1.4 episodes per year per person it was estimated that there would be 3.71 million symptomatic episodes of malaria among children Conclusion Malaria exacts a heavy toll on the health system in Malawi. The national recommendation of self-medication with first-line drug for uncomplicated malaria is justified as there are not enough clinicians to provide clinical care for all cases. The Malawi Ministry of Health's promotion of malaria drug prescription including other lower cadre health workers may be justified.

  19. Time required for disappearance of urate crystals from synovial fluid after successful hypouricaemic treatment relates to the duration of gout.

    Science.gov (United States)

    Pascual, Eliseo; Sivera, Francisca

    2007-08-01

    To determine whether hypouricaemic treatment results in the disappearance of urate crystals from gouty joints and to define the time required. In 18 patients with monosodium urate (MSU) crystal proven gout, and after the initiation of successful serum uric acid (SUA)-lowering treatment, an arthrocentesis of the asymptomatic signal joint (11 knees, 7 first metatarsophalangeal joints) was performed every 3 months to obtain a synovial fluid (SF) sample. The sample was then analysed for the presence of MSU crystals, and the number of crystals/400x field was noted. SUA levels and the duration of gout were also noted. MSU crystals disappeared from the SF of all 18 joints after reduction of SUA to normal levels. The time required for disappearance ranged from 3 to 33 months; disappearance time correlated with the duration of gout (r(s) = 0.71; pcrystals in the SF samples before urate-lowering treatment was 7.5 (2.5-11) crystals/400x field, reducing to 3 (1-6.5) crystals/400x field (pCrystal counts continued to decrease after 3 months. In gout, reduction of SUA to normal levels results in disappearance of urate crystals from SF, requiring a longer time in those patients with gout of longer duration. This indicates that urate crystal deposition in joints is reversible. Normalisation of SUA levels results in a decrease in the concentration of MSU crystals in SF in the asymptomatic gouty joints. This may partially explain the reduced frequency of gouty attacks when a patient has been treated with SUA-lowering drugs.

  20. Estimating pollutant removal requirements for landfills in the UK: I. Benchmark study and characteristics of waste treatment technologies.

    Science.gov (United States)

    Hall, D H; Drury, D; Gronow, J R; Rosevear, A; Pollard, S J T; Smith, R

    2006-12-01

    Introduction of the EU Landfill Directive is having a significant impact on waste management in the UK and in other member states that have relied on landfilling. This paper considers the length of the aftercare period required by the municipal solid waste streams that the UK will most probably generate following implementation of the Landfill Directive. Data were derived from literature to identify properties of residues from the most likely treatment processes and the probable management times these residues will require within the landfill environment were then modelled. Results suggest that for chloride the relevant water quality standard (250 mg l(-1)) will be achieved with a management period of 40 years and for lead (0.1 mg I(-1)), 240 years. This has considerable implications for the sustainability of landfill and suggests that current timescales for aftercare of landfills may be inadequate.

  1. Requirements Identification Towards a Design of Adaptive ICTs for Supporting Bipolar Disorder Treatment in Different Healthcare Contexts

    Directory of Open Access Journals (Sweden)

    Emanuele Torri

    2015-10-01

    Full Text Available This paper presents patient and caregiver perspective on ICTs supporting bipolar disorder management in multinational healthcare provisioning contexts. The envisioned mHealth solutions should adopt general requirements that could be instantiated into different clinical settings. Engagement of users in designing new technologies for mental health is crucial to ensure empowerment and patient-centeredness of services. We performed focus groups to understand user needs, attitudes and experiences towards the supportive ICTs in two target regions where the expected solutions will operate. The survey offered valuable inputs for the construction of the clinical requirements used to produce a trans-national call for tender on mobile health solutions aimed at supporting bipolar disorders treatment among public purchasers in different European countries. The study was part of the NYMHPA-MD (Next Generation Mobile Platform for Health in Mental Disorders project, co-funded by the European Commission.

  2. TRAINING OLDER WORKERS FOR TECHNOLOGY-BASED EMPLOYMENT.

    Science.gov (United States)

    Lee, Chin Chin; Czaja, Sara J; Sharit, Joseph

    2009-01-01

    An increasingly aging workforce and advances in technology are changing work environments and structures. The continued employability of older adults, particularly those of lower socioeconomic status (SES), requires them to participate in training programs to ensure their competence in today's workplace. Focus groups with 37 unemployed adults (51-76 years old) were conducted to gather information about barriers and obstacles for returning to work, training needs and formats, work experiences, and perceptions of the characteristics of an ideal job. Overall, results indicated that participants experienced age discrimination and lack of technology skills. They also expressed a desire to receive additional training on technology and a preference for classroom training.

  3. Technology-Based Healthcare for Nursing Education Within The Netherlands: Past, Present and Future.

    Science.gov (United States)

    Koster, Ybranda; van Houwelingen, Cornelis T M

    2017-01-01

    At the present time, nearly all Dutch nursing schools are searching for suitable ways to implement technology-based healthcare in their curriculum. Some Universities chose elective education, others a mandatory solution. Several studies were executed to determine competencies needed by nurses in order to work with technology-based healthcare. In 2016 a nationwide new curriculum for nurses has been published. Providing technology-based healthcare is included under the core competencies of this new curriculum. All baccalaureate nursing educational institutes must implement this new curriculum at the start of 2016 which will have a huge impact on the implementation of technology-based healthcare in the education programs. In the future, technology centers from Universities will collaborate and specialize, partner with technology companies and crossovers between information and communication technology and healthcare education will be expanded.

  4. Impact of Gender on Patient Preferences for Technology-Based Behavioral Interventions

    Directory of Open Access Journals (Sweden)

    David J. Kim

    2014-08-01

    Full Text Available Introduction: Technology-based interventions offer an opportunity to address high-risk behaviors in the emergency department (ED. Prior studies suggest behavioral health strategies are more effective when gender differences are considered. However, the role of gender in ED patient preferences for technology-based interventions has not been examined. The objective was to assess whether patient preferences for technology-based interventions varies by gender. Methods: This was a secondary analysis of data from a systematic survey of adult (18 years of age, English-speaking patients in a large urban academic ED. Subjects were randomly selected during a purposive sample of shifts. The iPad survey included questions on access to technology, preferences for receiving health information, and demographics. We defined ‘‘technology-based’’ as web, text message, e-mail, social networking, or DVD; ‘‘non-technology-based’’ was defined as in-person, written materials, or landline. We calculated descriptive statistics and used univariate tests to compare men and women. Gender-stratified multivariable logistic regression models were used to examine associations between other demographic factors (age, race, ethnicity, income and technology-based preferences for information on specific risky behaviors. Results: Of 417 participants, 45.1% were male. There were no significant demographic differences between men and women. Women were more likely to use computers (90.8% versus 81.9%; p¼0.03, Internet (66.8% versus 59.0%; p¼0.03, and social networks (53.3% versus 42.6%; p¼0.01. 89% of men and 90% of women preferred technology-based formats for at least type of health information; interest in technology-based for individual health topics did not vary by gender. Concern about confidentiality was the most common barrier to technology-based use for both genders. Multivariate analysis showed that for smoking, depression, drug/alcohol use, and injury

  5. Aesthetic Design as an Element of Service Innovation in New Technology-based Firms

    OpenAIRE

    Candi, Marina

    2008-01-01

    The goals of this thesis are to examine new technology-based firms’ use of aesthetic design as an element of service innovation and to explore potential relationships between aesthetic design and performance in this same context. There is a scarcity of research on aesthetic design as an element of service innovation, particularly in new technology-based firms. Because of this scarcity, a hybrid research strategy is appropriate and the empirical basis for this research encompasses multiple cas...

  6. TRAINING OLDER WORKERS FOR TECHNOLOGY-BASED EMPLOYMENT

    Science.gov (United States)

    Lee, Chin Chin; Czaja, Sara J.; Sharit, Joseph

    2009-01-01

    An increasingly aging workforce and advances in technology are changing work environments and structures. The continued employability of older adults, particularly those of lower socioeconomic status (SES), requires them to participate in training programs to ensure their competence in today’s workplace. Focus groups with 37 unemployed adults (51–76 years old) were conducted to gather information about barriers and obstacles for returning to work, training needs and formats, work experiences, and perceptions of the characteristics of an ideal job. Overall, results indicated that participants experienced age discrimination and lack of technology skills. They also expressed a desire to receive additional training on technology and a preference for classroom training. PMID:20351795

  7. Engineering Technology Reports, Volume 2: Technology Base FY00

    Energy Technology Data Exchange (ETDEWEB)

    Baron, A L; Langland, R T; Minichino, C

    2001-10-03

    In FY-2000, Engineering at Lawrence Livermore National Laboratory faced significant pressures to meet critical project milestones, and immediate demands to facilitate the reassignment of employees as the National Ignition Facility (the 600-TW laser facility being designed and built at Livermore, and one of the largest R&D construction projects in the world) was in the process of re-baselining its plan while executing full-speed its technology development efforts. This drive for change occurred as an unprecedented level of management and program changes were occurring within LLNL. I am pleased to report that we met many key milestones and achieved numerous technological breakthroughs. This report summarizes our efforts to perform feasibility and reduce-to-practice studies, demonstrations, and/or techniques--as structured through our technology centers. Whether using computational engineering to predict how giant structures like suspension bridges will respond to massive earthquakes or devising a suitcase-sized microtool to detect chemical and biological agents used by terrorists, we have made solid technical progress. Five Centers focus and guide longer-term investments within Engineering, as well as impact all of LLNL. Each Center is responsible for the vitality and growth of the core technologies it represents. My goal is that each Center will be recognized on an international scale for solving compelling national problems requiring breakthrough innovation. The Centers and their leaders are as follows: Center for Complex Distributed Systems--David B. McCallen; Center for Computational Engineering--Kyran D. Mish; Center for Microtechnology--Raymond P. Mariella, Jr.; Center for Nondestructive Characterization--Harry E. Martz, Jr.; and Center for Precision Engineering--Keith Carlisle.

  8. 3D printing technology based on two-photon polymerization%双光子聚合3D打印

    Institute of Scientific and Technical Information of China (English)

    宋晓艳; 邢金峰

    2015-01-01

    3D 打印是一种快速成型的增材制造技术.光固化立体印刷(SLA)是技术较成熟和应用较广的一种 3D 打印技术.SLA 是采用紫外激光的单光子聚合过程,其加工分辨率受经典光学衍射极限的限制,难以满足分辨率高的微纳结构的加工.不同于 SLA,利用近红外波长飞秒激光的双光子聚合 3D 打印技术可以突破经典光学衍射的限制,制造分辨率高的纳米尺度任意形状三维结构.本文将介绍双光子吸收和双光子聚合的原理、双光子聚合的发展和双光子聚合 3D 打印技术的应用,最后对该技术的发展进行展望.%3D printing is a rapid prototyping technology based on an additive process. Stereolithography (SLA) as a mature 3D printing technology has been widely applied in industrial manufacture. SLA is the process of single-photon polymerization (SPP), and its resolution is controlled by the optical diffraction limit, which cannot meet the requirement for three dimensional micro/nanostructures with high resolution. Unlike SLA, 3D printing technology based on two-photon polymerization (TPP) induced by a near-infrared femtosecond laser can fabricate arbitrary and ultraprecise 3D microstructures with high resolution not only on the microscopic scale but also on the nanoscale. In this review, the principles of two-photon absorption and TPP were concisely explained. The development of TPP mainly focusing on TPP resolution and TPP initiators were introduced as well as the applications of 3D printing technology based on TPP. Finally, the perspective of 3D printing technology based on TPP was proposed.

  9. Information and communication technology-based cardiac rehabilitation homecare programs

    Directory of Open Access Journals (Sweden)

    Varnfield M

    2015-04-01

    . However, change in the existing CR services is not without challenges. There is a need to identify development issues that can hamper the implementation of the interventions outside controlled trial settings systems, which may require new computing infrastructures, specific clinical responsibilities, time for training, and development and openness to new ways of doing things.Keywords: cardiovascular disease, Telehealth, telephone, Internet, mobile phones

  10. Determining treatment requirements for turbid river water to avoid clogging of aquifer storage and recovery wells in siliceous alluvium.

    Science.gov (United States)

    Page, Declan; Vanderzalm, Joanne; Miotliński, Konrad; Barry, Karen; Dillon, Peter; Lawrie, Ken; Brodie, Ross S

    2014-12-01

    The success of Aquifer Storage and Recovery (ASR) schemes relies on defining appropriate design and operational parameters in order to maintain high rates of recharge over the long term. The main contribution of this study was to define the water quality criteria and hence minimum pre-treatment requirements to allow sustained recharge at an acceptable rate in a medium-coarse sand aquifer. The source water was turbid, natural water from the River Darling, Australia. Three treatments were evaluated: bank filtration; coagulation and chlorine disinfection; and coagulation plus granular activated carbon and chlorine disinfection (GAC). Raw source water and the three treated waters were used in laboratory columns packed with aquifer material in replicate experiments in saturated conditions at constant temperature (19 °C) with light excluded for 37 days. Declines in hydraulic conductivity from a mean of 2.17 m/d occurred over the 37 days of the experiment. The GAC-treated water gave an 8% decline in hydraulic conductivity over the 16 cm length of columns, which was significantly different from the other three source waters, which had mean declines of 26-29%. Within the first 3 cm of column length, where most clogging occurred in each column, the mean hydraulic conductivity declined by 10% for GAC-treated water compared with 40-50% for the other source waters. There was very little difference between the columns until day 21, despite high turbidity (78 NTU) in the source water. Reducing turbidity by treatment was not sufficient to offset the reductions in hydraulic conductivity. Biological clogging was found to be most important as revealed by the accumulation of polysaccharides and bacterial numbers in columns when they were dissected and analysed at the end of the experiment. Further chemical clogging through precipitation of minerals was found not to occur within the laboratory columns, and dispersion of clay was also found to be negligible. Due to the low

  11. 40 CFR Appendix J to Part 122 - NPDES Permit Testing Requirements for Publicly Owned Treatment Works (§ 122.21(j))

    Science.gov (United States)

    2010-07-01

    ... Publicly Owned Treatment Works (§ 122.21(j)) J Appendix J to Part 122 Protection of Environment... POLLUTANT DISCHARGE ELIMINATION SYSTEM Pt. 122, App. J Appendix J to Part 122—NPDES Permit Testing Requirements for Publicly Owned Treatment Works (§ 122.21(j)) Table 1A—Effluent Parameters for All...

  12. Internet of Things technology-based management methods for environmental specimen banks.

    Science.gov (United States)

    Peng, Lihong; Wang, Qian; Yu, Ang

    2015-02-01

    The establishment and management of environmental specimen banks (ESBs) has long been a problem worldwide. The complexity of specimen environment has made the management of ESB likewise complex. Through an analysis of the development and management of ESBs worldwide and in light of the sophisticated Internet of Things (IOT) technology, this paper presents IOT technology-based ESB management methods. An IOT technology-based ESB management system can significantly facilitate ESB ingress and egress management as well as long-term storage management under quality control. This paper elaborates on the design of IOT technology-based modules, which can be used in ESB management to achieve standardized, smart, information-based ESB management. ESB management has far-reaching implications for environmental management and for research in environmental science.

  13. Technology-based interventions in social work practice: a systematic review of mental health interventions.

    Science.gov (United States)

    Ramsey, Alex T; Montgomery, Katherine

    2014-10-01

    Despite concerns around the use of technology-based interventions, they are increasingly being employed by social workers as a direct practice methodology to address the mental health needs of vulnerable clients. Researchers have highlighted the importance of using innovative technologies within social work practice, yet little has been done to summarize the evidence and collectively assess findings. In this systematic review, we describe accounts of technology-based mental health interventions delivered by social workers over the past 10 years. Results highlight the impacts of these tools and summarize advantages and disadvantages to utilizing technologies as a method for delivering or facilitating interventions.

  14. Contribution of the analytic hierarchy process (AHP method for supporting the decision to outsource or internalize activities in the context of technology-based company

    Directory of Open Access Journals (Sweden)

    Luciana Paula Reis

    2013-11-01

    Full Text Available The definition of business model requires, among other decisions, the structure of the value chain of an emerging new organization. This structure depends on the decision to outsource or internalize sets of processes and their activities. This decision fundamentally strategic, demand a correct definition of the activities that actually add value to the business, and therefore desirable a methodology able to assist the manager in the process of decision making. This paper aims to propose a process to aid decision to outsource or internalize activities in the context of a technology-based company, using the strategy of action research methods associated with the Analytic Hierarchy Process (AHP and focus group technique. The study has resulted in the structuring of the decision process and criteria relevant to the identification of activities to be internalized by the technology-based company.

  15. Technology-Based Biliteracy Centers for the 21st Century Learner

    Science.gov (United States)

    Mercuri, Sandra; Ramos, Laura

    2014-01-01

    The purpose of this reflective article is to present an alternative that incorporates the four language skills in all content areas through technology-based dual-language centers for emergent bilinguals at the elementary level. The authors propose a matrix to plan the centers and include three examples to facilitate language transfer in English…

  16. Silicon-technology based microreactors for high-temperature heterogeneous partial oxidation reactions

    NARCIS (Netherlands)

    Tiggelaar, Roald Michel

    2004-01-01

    In this thesis the results of a study into the feasibility of silicon-technology based microreactors for fast oxidation reactions have been discussed. When designed properly, silicon microreactors are suitable for studying heterogeneous gas phase reactions, such as reaction kinetics of direct cataly

  17. Motivations of Women Participating in a Technology-Based Social Entrepreneurship Program

    Science.gov (United States)

    Dzombak, Rachel; Mouakkad, Sally; Mehta, Khanjan

    2016-01-01

    Academic programs focused on engineering entrepreneurship are growing in number and popularity at American universities. However, the fields of engineering, entrepreneurship and technology-based entrepreneurship struggle to recruit and retain female students: a historic and endemic failure at obtaining gender-balanced participation. Understanding…

  18. Teachers' Beliefs and Practices in Technology-Based Classrooms: A Developmental View

    Science.gov (United States)

    Levin, Tamar; Wadmany, Rivka

    2006-01-01

    This paper reports on an exploratory, longitudinal study that analyzes and interprets the evolution of teachers' beliefs regarding learning, teaching, and technology, and their instructional practices, in the context of integrating technology-based information-rich tasks in six 4th-6th grade classrooms. The study used multiple research tools,…

  19. Mandatory use of technology-based self-service: does expertise help or hurt?

    NARCIS (Netherlands)

    Reinders, Machiel J.; Frambach, Ruud; Kleijnen, Mirella

    2015-01-01

    Purpose – This study aims to investigate the effects of two types of expertise (self-service technology and service type) on the disconfirmation of customers’ expectations and the use-related outcomes of technology-based self-service (TBSS).
    Design/methodology/approach – This empirical study pe

  20. Technology-based service proposal screening and decision-making effectiveness

    NARCIS (Netherlands)

    Riel, van Allard C.R.; Semeijn, Janjaap; Hammedi, Wafa; Henseler, Jörg

    2011-01-01

    Purpose – Decision-making in early stages of technology-based service (TBS) innovation projects proves to be challenging. Current failure rates in service innovation are high, while the investments in innovation projects are substantial. Research suggests that enhancing decision-making in the screen

  1. Innovation capabilities in food and beverages and technology-based innovation projects

    NARCIS (Netherlands)

    Tepic, M.; Fortuin, F.T.J.M.; Kemp, R.G.M.; Omta, S.W.F.

    2014-01-01

    Purpose - The aim of this paper is to establish the differences between the food and beverages (F&B) and technology-based industries with regards to the relation between previously identified success factors and innovation project performance. Design/methodology/approach - These differences are

  2. Innovative Technology-Based Interventions for Autism Spectrum Disorders: A Meta-Analysis

    Science.gov (United States)

    Grynszpan, Ouriel; Weiss, Patrice L.; Perez-Diaz, Fernando; Gal, Eynat

    2014-01-01

    This article reports the results of a meta-analysis of technology-based intervention studies for children with autism spectrum disorders. We conducted a systematic review of research that used a pre-post design to assess innovative technology interventions, including computer programs, virtual reality, and robotics. The selected studies provided…

  3. Consumer acceptance of technology-based food innovations: Lessons for the future of nutrigenomics

    NARCIS (Netherlands)

    Ronteltap, A.; Trijp, van J.C.M.; Renes, R.J.; Frewer, L.J.

    2007-01-01

    Determinants of consumer adoption of innovations have been studied from different angles and from the perspectives of various disciplines. In the food area, the literature is dominated by a focus on consumer concern. This paper reviews previous research into acceptance of technology-based innovation

  4. Consequences of Forcing Consumers to Use Technology-Based Self-Service

    NARCIS (Netherlands)

    Reinders, M.J.; Dabholkar, P.A.; Frambach, R.T.

    2008-01-01

    Today, traditional full service is increasingly replaced with technology-based self-service (TBSS), sometimes with no other option for service delivery. This study develops a conceptual model to investigate the impact of forcing consumers to use TBSS. The model is tested using an experimental design

  5. Technology-Based Content through Virtual and Physical Modeling: A National Research Study

    Science.gov (United States)

    Ernst, Jeremy V.; Clark, Aaron C.

    2009-01-01

    Visualization is becoming more prevalent as an application in science, engineering, and technology related professions. The analysis of static and dynamic graphical visualization provides data solutions and understandings that go beyond traditional forms of communication. The study of technology-based content and the application of conceptual…

  6. Innovation capabilities in food and beverages and technology-based innovation projects

    NARCIS (Netherlands)

    Tepic, M.; Fortuin, F.T.J.M.; Kemp, R.G.M.; Omta, S.W.F.

    2014-01-01

    Purpose - The aim of this paper is to establish the differences between the food and beverages (F&B) and technology-based industries with regards to the relation between previously identified success factors and innovation project performance. Design/methodology/approach - These differences are

  7. A technology-based stimulation program to reduce hand mouthing by an adolescent with multiple disabilities

    NARCIS (Netherlands)

    Lancioni, G.E.; Singh, N.N.; O'Reilly, M.F.; Didden, H.C.M.; Oliva, D.

    2009-01-01

    This study assessed the possibility of reducing hand mouthing, i.e., bringing fingers into or over the mouth, by an adolescent with multiple disabilities through a technology-based stimulation strategy. The strategy ensured that (a) the participant received 10 sec. of preferred stimulation

  8. A Constructivist Stretch: Preservice Teachers Meet Preteens in a Technology-Based Literacy Project.

    Science.gov (United States)

    Bauer, John F.; Anderson, Rebecca S.

    2002-01-01

    Describes a study conducted within a constructivist framework to examine pre-service teachers' development and implementation of a collaborative, technology-based literacy project with 11- and 12-year-old learners. Concludes that the pre-service teachers learned the value of Internet technology, e-mail, and hypermedia applications, but problems…

  9. Technology-Based Participatory Learning for Indigenous Children in Chiapas Schools, Mexico

    Science.gov (United States)

    Heredia, Yolanda; Icaza, Jose I.

    2012-01-01

    This research created a technology-based learning environment at two schools belonging to the National Council of Educational Development (CONAFE) for indigenous children in the state of Chiapas, Mexico. The purpose of the study was to describe the educational impact of using the Classmate PC netbooks and the Sugar Educational Platform in the…

  10. A New Direction for Technology-Based Economic Development: The Role of Innovation Intermediaries

    Science.gov (United States)

    Bendis, Richard A.; Seline, Richard S.; Byler, Ethan J.

    2008-01-01

    Accelerating innovation to drive economic growth is the foremost goal for technology-based economic development organizations today. Realizing this goal through programmes is challenged by limited and outdated operating models. The authors outline their 21st Century Innovation Intermediary model, which pairs commercialization with regional…

  11. VATE: VAlidation of high TEchnology based on large database analysis by learning machine

    NARCIS (Netherlands)

    Meldolesi, E; Van Soest, J; Alitto, A R; Autorino, R; Dinapoli, N; Dekker, A; Gambacorta, M A; Gatta, R; Tagliaferri, L; Damiani, A; Valentini, V

    2014-01-01

    The interaction between implementation of new technologies and different outcomes can allow a broad range of researches to be expanded. The purpose of this paper is to introduce the VAlidation of high TEchnology based on large database analysis by learning machine (VATE) project that aims to combine

  12. Dynamic capabilities and the growth of technology-based new ventures

    NARCIS (Netherlands)

    Strehle, Florian Thomas

    2006-01-01

    Under the influence of increasing globalisation the creation and development of technology-based entrepreneurial firms is considered a prevalent means to fuel economic growth and prevent further unemployment, especially in Western European economies. This dissertation denotes the process of new vent

  13. Bringing Technology to Students' Proximity: A Sociocultural Account of Technology-Based Learning Projects

    Science.gov (United States)

    Mukama, Evode

    2014-01-01

    This paper depicts a study carried out in Rwanda concerning university students who participated in a contest to produce short documentary films. The purpose of this research is to conceptualize these kinds of technology-based learning projects (TBLPs) through a sociocultural perspective. The methodology included focus group discussions and field…

  14. An Educational and Entrepreneurial Ecosystem to Actualize Technology-Based Social Ventures

    Science.gov (United States)

    Mehta, Khanjan; Zappe, Sarah; Brannon, Mary Lynn; Zhao, Yu

    2016-01-01

    The Humanitarian Engineering and Social Entrepreneurship (HESE) Program engages students and faculty across Penn State in the rigorous research, design, field-testing, and launch of technology-based social enterprises that address global development challenges. HESE ventures are embedded in a series of five courses that integrate learning,…

  15. Dynamic capabilities and the growth of technology-based new ventures

    NARCIS (Netherlands)

    Strehle, Florian Thomas

    2006-01-01

    Under the influence of increasing globalisation the creation and development of technology-based entrepreneurial firms is considered a prevalent means to fuel economic growth and prevent further unemployment, especially in Western European economies. This dissertation denotes the process of new vent

  16. Designing a Technology-Based Science Lesson: Student Teachers Grapple with an Authentic Problem of Practice

    Science.gov (United States)

    Butler, Susan McAleenan; Wiebe, Eric N.

    2003-01-01

    This project used techniques from problem-based learning to aid students in developing a technology-based science lesson. In this case, the "problem" students were asked to solve, was that of combining curriculum knowledge and pedagogical skills to incorporate computer graphics animation technology within a science lesson and then teach the lesson…

  17. The SUMO protease SENP1 is required for cohesion maintenance and mitotic arrest following spindle poison treatment

    Energy Technology Data Exchange (ETDEWEB)

    Era, Saho [Fondazione IFOM, Istituto FIRC di Oncologia Molecolare, IFOM-IEO campus, Via Adamello 16, 20139 Milan (Italy); Radiation Genetics, Graduate School of Medicine, Kyoto University, Yoshida-Konoe, Sakyo-ku, Kyoto 606-8501 (Japan); Abe, Takuya; Arakawa, Hiroshi [Fondazione IFOM, Istituto FIRC di Oncologia Molecolare, IFOM-IEO campus, Via Adamello 16, 20139 Milan (Italy); Kobayashi, Shunsuke [Radiation Genetics, Graduate School of Medicine, Kyoto University, Yoshida-Konoe, Sakyo-ku, Kyoto 606-8501 (Japan); Szakal, Barnabas [Fondazione IFOM, Istituto FIRC di Oncologia Molecolare, IFOM-IEO campus, Via Adamello 16, 20139 Milan (Italy); Yoshikawa, Yusuke; Motegi, Akira; Takeda, Shunichi [Radiation Genetics, Graduate School of Medicine, Kyoto University, Yoshida-Konoe, Sakyo-ku, Kyoto 606-8501 (Japan); Branzei, Dana, E-mail: dana.branzei@ifom.eu [Fondazione IFOM, Istituto FIRC di Oncologia Molecolare, IFOM-IEO campus, Via Adamello 16, 20139 Milan (Italy)

    2012-09-28

    Highlights: Black-Right-Pointing-Pointer SENP1 knockout chicken DT40 cells are hypersensitive to spindle poisons. Black-Right-Pointing-Pointer Spindle poison treatment of SENP1{sup -/-} cells leads to increased mitotic slippage. Black-Right-Pointing-Pointer Mitotic slippage in SENP1{sup -/-} cells associates with apoptosis and endoreplication. Black-Right-Pointing-Pointer SENP1 counteracts sister chromatid separation during mitotic arrest. Black-Right-Pointing-Pointer Plk1-mediated cohesion down-regulation is involved in colcemid cytotoxicity. -- Abstract: SUMO conjugation is a reversible posttranslational modification that regulates protein function. SENP1 is one of the six SUMO-specific proteases present in vertebrate cells and its altered expression is observed in several carcinomas. To characterize SENP1 role in genome integrity, we generated Senp1 knockout chicken DT40 cells. SENP1{sup -/-} cells show normal proliferation, but are sensitive to spindle poisons. This hypersensitivity correlates with increased sister chromatid separation, mitotic slippage, and apoptosis. To test whether the cohesion defect had a causal relationship with the observed mitotic events, we restored the cohesive status of sister chromatids by introducing the TOP2{alpha}{sup +/-} mutation, which leads to increased catenation, or by inhibiting Plk1 and Aurora B kinases that promote cohesin release from chromosomes during prolonged mitotic arrest. Although TOP2{alpha} is SUMOylated during mitosis, the TOP2{alpha}{sup +/-} mutation had no obvious effect. By contrast, inhibition of Plk1 or Aurora B rescued the hypersensitivity of SENP1{sup -/-} cells to colcemid. In conclusion, we identify SENP1 as a novel factor required for mitotic arrest and cohesion maintenance during prolonged mitotic arrest induced by spindle poisons.

  18. Synthesis of Collaborative Learning Processes with Technology Based Education to Enhance Classroom Teaching

    Science.gov (United States)

    Ghosh, Sumit

    2016-07-01

    A major hurdle in school education in India is the presence of large number of teachers who are inexperienced and have merely taken up the profession of teaching only after exhausting all avenues or getting rejected from all quarters. Empowering and training such teachers with information is a herculean task. Students tend to pay attention and show enthusiasm in learning when they view the class as relevant to themselves and connected to their interests. The current teaching-learning methods for teaching science and astronomy have become obsolete and require a major overhaul. A teaching-learning process which concentrates on an explorative-collaborative-comprehending methodology with simultaneous combination of technology has been developed with the objective to reignite the scientific temper among the future budding scientists. Attaining this goal will be possible when instructors adopt a bottom-up approach, which involves understanding the student's needs, designing flexible course content and synchronizing teaching techniques that focus on increasing student engagement by making the learning experience meaningful and purposeful. The International Year of Light (IYL 2015) is a global initiative that highlights to the citizens of the world the importance of light and optical technologies in their lives, for their futures, and for the development of society. One of the strong legacies left by the 2009 International Year of Astronomy was to use Astronomy in making the world a better place. On the eve of IYL 2015, an Optical Society funded outreach program, 'Spark of Light' was organised for under-privileged school children by using the explorative-collaborative-technology based mechanism and make them understand the nature and properties of light with emphasis on how Astronomy has been crucial for the evolution of sophisticated technology. A major paradigm shift from our previous program was the engagement of such untrained teachers in each and every aspect of

  19. Complication Reducing Effect of the Information Technology-Based Diabetes Management System on Subjects with Type 2 Diabetes

    Science.gov (United States)

    Cho, Jae-Hyoung; Lee, Jin-Hee; Oh, Jeong-Ah; Kang, Mi-Ja; Choi, Yoon-Hee; Kwon, Hyuk-Sang; Chang, Sang-Ah; Cha, Bong-Yun; Son, Ho-Young; Yoon, Kun-Ho

    2008-01-01

    Objective We introduced a new information technology-based diabetes management system, called the Internet-based glucose monitoring system (IBGMS), and demonstrated its short-term and long-term favorable effects. However, there has been no report on clinical effects of such a new diabetes management system on the development of diabetic complications so far. This study was used to simulate the complication reducing effect of the IBGMS, given in addition to existing treatments in patients with type 2 diabetes. Research Design and Methods The CORE Diabetes Model, a peer-reviewed, published, validated computer simulation model, was used to project long-term clinical outcomes in type 2 diabetes patients receiving the IBGMS in addition to their existing treatment. The model combined standard Markov submodels to simulate the incidence and progression of diabetes-related complications. Results The addition of IBGMS was associated with improvements in reducing diabetic complications, mainly microangiopathic complications, including diabetic retinopathy, diabetic neuropathy, diabetic nephropathy, and diabetic foot ulcer. The IBGMS also delayed the development of all diabetic complications for more than 1 year. Conclusions This study demonstrated that the simulated IBGMS, compared to existing treatment, was associated with a reduction of diabetic complications. As a result, it provides valuable evidence for practical application to the public in the world. PMID:19885180

  20. Sample size requirements for studies of treatment effects on beta-cell function in newly diagnosed type 1 diabetes.

    Directory of Open Access Journals (Sweden)

    John M Lachin

    Full Text Available Preservation of β-cell function as measured by stimulated C-peptide has recently been accepted as a therapeutic target for subjects with newly diagnosed type 1 diabetes. In recently completed studies conducted by the Type 1 Diabetes Trial Network (TrialNet, repeated 2-hour Mixed Meal Tolerance Tests (MMTT were obtained for up to 24 months from 156 subjects with up to 3 months duration of type 1 diabetes at the time of study enrollment. These data provide the information needed to more accurately determine the sample size needed for future studies of the effects of new agents on the 2-hour area under the curve (AUC of the C-peptide values. The natural log(x, log(x+1 and square-root (√x transformations of the AUC were assessed. In general, a transformation of the data is needed to better satisfy the normality assumptions for commonly used statistical tests. Statistical analysis of the raw and transformed data are provided to estimate the mean levels over time and the residual variation in untreated subjects that allow sample size calculations for future studies at either 12 or 24 months of follow-up and among children 8-12 years of age, adolescents (13-17 years and adults (18+ years. The sample size needed to detect a given relative (percentage difference with treatment versus control is greater at 24 months than at 12 months of follow-up, and differs among age categories. Owing to greater residual variation among those 13-17 years of age, a larger sample size is required for this age group. Methods are also described for assessment of sample size for mixtures of subjects among the age categories. Statistical expressions are presented for the presentation of analyses of log(x+1 and √x transformed values in terms of the original units of measurement (pmol/ml. Analyses using different transformations are described for the TrialNet study of masked anti-CD20 (rituximab versus masked placebo. These results provide the information needed to

  1. Functional Management Competence and Growth of Young Technology-Based Firms

    DEFF Research Database (Denmark)

    Salomo, Søren; Brinckmann, Jan; Talke, Katrin

    2008-01-01

    based on partial least squares modelling to investigate the performance effects. The results suggest that functional management competences generally are significant drivers of firm development speed. In particular, technology and marketing management competences are shown to impact development speed...... at delineating and validating an appropriate measurement model for functional management competence. In order to test the model's nomological validity, we investigate the impact of functional management competence on firm growth. Therefore, building on established firm development approaches, we propose a phase...... model for the development of young technology-based firms. Our study builds upon data from 212 young technology-based firms in the field of microtechnology, nanotechnology, electronics, optics and lasers. We use formative measurement models to establish valid and reliable constructs and a path model...

  2. Research progress of laser welding process dynamic monitoring technology based on plasma characteristics signal

    Directory of Open Access Journals (Sweden)

    Teng WANG

    2017-02-01

    Full Text Available During the high-power laser welding process, plasmas are induced by the evaporation of metal under laser radiation, which can affect the coupling of laser energy and the workpiece, and ultimately impact on the reliability of laser welding quality and process directly. The research of laser-induced plasma is a focus in high-power deep penetration welding field, which provides a promising research area for realizing the automation of welding process quality inspection. In recent years, the research of laser welding process dynamic monitoring technology based on plasma characteristics is mainly in two aspects, namely the research of plasma signal detection and the research of laser welding process modeling. The laser-induced plasma in the laser welding is introduced, and the related research of laser welding process dynamic monitoring technology based on plasma characteristics at home and abroad is analyzed. The current problems in the field are summarized, and the future development trend is put forward.

  3. 75 FR 13305 - Comment Request for Information Collection for Evaluation of the Technology-Based Learning Grants...

    Science.gov (United States)

    2010-03-19

    ... comments concerning a new data collection effort for the Technology- Based Learning Grants Evaluation. A... Evaluation of the Technology-Based Learning (TBL) Grants is a two-year evaluation of grantees funded under... Employment and Training Administration Comment Request for Information Collection for Evaluation of the...

  4. Introductory Statistics, College Student Attitudes and Knowledge--A Qualitative Analysis of the Impact of Technology-Based Instruction

    Science.gov (United States)

    Meletiou-Mavrotheris, M.; Lee, C.; Fouladi, R. T.

    2007-01-01

    This paper presents findings from a qualitative study that compared the learning experiences of a group of students from a technology-based college-level introductory statistics course with the learning experiences of a group of students with non-technology-based instruction. Findings from the study indicate differences with regards to classroom…

  5. Management of the obstructive sleep apnoea syndrome: More knowledge required for an optimal choice of treatment modality

    NARCIS (Netherlands)

    Hoekema, A

    2006-01-01

    In the management of the obstructive sleep apnoea syndrome (OSAS), clinicians may consider various conservative, non-invasive and surgical treatment modalities. Continuous positive airway pressure (CPAP) is regarded as the treatment of choice for, especially, moderate to severe OSAS. However, due to

  6. Management of the obstructive sleep apnoea syndrome: More knowledge required for an optimal choice of treatment modality

    NARCIS (Netherlands)

    Hoekema, A

    2006-01-01

    In the management of the obstructive sleep apnoea syndrome (OSAS), clinicians may consider various conservative, non-invasive and surgical treatment modalities. Continuous positive airway pressure (CPAP) is regarded as the treatment of choice for, especially, moderate to severe OSAS. However, due to

  7. Adolescents' preference for technology-based emergency department behavioral interventions: does it depend on risky behaviors?

    Science.gov (United States)

    Ranney, Megan L; Choo, Esther K; Spirito, Anthony; Mello, Michael J

    2013-04-01

    This study aimed to (1) determine the prevalence of technology use and interest in technology-based interventions among adolescent emergency department patients and (2) examine the association between interest in an intervention and self-reported risky behaviors. Adolescents (age, 13-17 years) presenting to an urban pediatric emergency department completed a survey regarding baseline technology use, risky behaviors, and interest in and preferred format for behavioral health interventions. Questions were drawn from validated measures when possible. Descriptive statistics and χ2 tests were calculated to identify whether self-reported risky behaviors were differentially associated with intervention preference. Two hundred thirty-four patients (81.8% of eligible) consented to participate. Almost all used technology, including computers (98.7%), social networking (84.9%), and text messaging (95.1%). Adolescents reported high prevalence of risky behaviors as follows: unintentional injury (93.2%), peer violence exposure (29.3%), dating violence victimization (23.0%), depression or anxiety (30.0%), alcohol use (22.8%), drug use (36.1%), cigarette use (16.4%), and risky sexual behaviors (15.1%). Most were interested in receiving behavioral interventions (ranging from 93.6% interest in unintentional injury prevention, to 73.1% in smoking cessation); 45% to 93% preferred technology-based (vs in person, telephone call, or paper) interventions for each topic. Proportion interested in a specific topic and proportion preferring a technology-based intervention did not significantly differ by self-reported risky behaviors. Among this sample of adolescent emergency department patients, high rates of multiple risky behaviors are reported. Patients endorsed interest in receiving interventions for these behaviors, regardless of whether they reported the behavior. Most used multiple forms of technology, and approximately 50% preferred a technology-based intervention format.

  8. Market Segmentation in Business Technology Base: The Case of Segmentation of Sparkling

    OpenAIRE

    Valéria Riscarolli; Universidade Nove de Julho - UNINOVE; Sandra Regina Silva dos Santos Souza; Universidade Nove de Julho - UNINOVE; Leonel Cezar Rodrigues; Universidade Nove de Julho - UNINOVE; Fabrícia Durieux Zucco; FURB e UNIVALI

    2014-01-01

    A common market segmentation premise for products and services rules consumer behavior as the segmentation center piece. Would this be the logic for segmentation used by small technology based companies? In this article we target at determining the principles of market segmentation used by a vitiwinery company, as research object. This company is recognized by its products excellence, either in domestic as well as in the foreign market, among 13 distinct countries. The research method used is...

  9. Technology-based strategies for promoting clinical reasoning skills in nursing education.

    Science.gov (United States)

    Shellenbarger, Teresa; Robb, Meigan

    2015-01-01

    Faculty face the demand of preparing nursing students for the constantly changing health care environment. Effective use of online, classroom, and clinical conferencing opportunities helps to enhance nursing students' clinical reasoning capabilities needed for practice. The growth of technology creates an avenue for faculty to develop engaging learning opportunities. This article presents technology-based strategies such as electronic concept mapping, electronic case histories, and digital storytelling that can be used to facilitate clinical reasoning skills.

  10. Bringing technology to students’ proximity: a sociocultural account of technology-based learning projects

    OpenAIRE

    Evode Mukama

    2014-01-01

    This paper depicts a study carried out in Rwanda concerning university students who participated in a contest to produce short documentary films. The purpose of this research is to conceptualize these kinds of technology-based learning projects (TBLPs) through a sociocultural perspective. The methodology included focus-group discussions and field notes to collect empirical data. The findings reveal that the more educational technologies capture objects of learning positioned in the students’ ...

  11. From Ideas to Opportunities: Exploring the Construction of Technology-Based Entrepreneurial Opportunities

    Directory of Open Access Journals (Sweden)

    Ferran Giones

    2013-06-01

    Full Text Available The transformation of business ideas into market opportunities is at the core of entrepreneurship. Nevertheless, the complexity of such a transformative process is seen to change depending on the variables influencing the opportunity-entrepreneur nexus. Although technology-entrepreneurship is regarded as a force of change and dynamism in socio-economic growth, it also depends upon an intricate process of opportunity development. The interest in understanding better how technology-based entrepreneurs simultaneously cope with technological uncertainty while trying to gain stakeholder support and access to resources, highlights a relevant research gap. The research described in this article uses the constructivist view to deepen our understanding of the technology-based entrepreneur’s conceptualization of the opportunity as a process of social construction. Our results show how initial consensus-building efforts and iteration with knowledgeable peers are an essential part of the emergence of the opportunity, changing both entrepreneur's and stakeholders' perceptions of the early business idea. Consequently, our results provide evidence in support of policy programs and measures that favour social-construction support mechanisms to foster technology-based entrepreneurship.

  12. Technology-based self-care methods of improving antiretroviral adherence: a systematic review.

    Directory of Open Access Journals (Sweden)

    Parya Saberi

    Full Text Available As HIV infection has shifted to a chronic condition, self-care practices have emerged as an important topic for HIV-positive individuals in maintaining an optimal level of health. Self-care refers to activities that patients undertake to maintain and improve health, such as strategies to achieve and maintain high levels of antiretroviral adherence.Technology-based methods are increasingly used to enhance antiretroviral adherence; therefore, we systematically reviewed the literature to examine technology-based self-care methods that HIV-positive individuals utilize to improve adherence. Seven electronic databases were searched from 1/1/1980 through 12/31/2010. We included quantitative and qualitative studies. Among quantitative studies, the primary outcomes included ARV adherence, viral load, and CD4+ cell count and secondary outcomes consisted of quality of life, adverse effects, and feasibility/acceptability data. For qualitative/descriptive studies, interview themes, reports of use, and perceptions of use were summarized. Thirty-six publications were included (24 quantitative and 12 qualitative/descriptive. Studies with exclusive utilization of medication reminder devices demonstrated less evidence of enhancing adherence in comparison to multi-component methods.This systematic review offers support for self-care technology-based approaches that may result in improved antiretroviral adherence. There was a clear pattern of results that favored individually-tailored, multi-function technologies, which allowed for periodic communication with health care providers rather than sole reliance on electronic reminder devices.

  13. 78 FR 31571 - Announcement of Requirements and Registration for the “Technology-based Products to Prevent High...

    Science.gov (United States)

    2013-05-24

    ... transmitted diseases, academic difficulties, suicide attempts, and alcohol dependence. This challenge seeks... preventing high-risk drinking among college students will save lives, improve academic success, and decrease... already impaired by another cause, such as depression or emotional stress; and combining alcohol...

  14. Development of a technology-based behavioral vaccine to prevent adolescent depression: A health system integration model

    Directory of Open Access Journals (Sweden)

    Benjamin W. Van Voorhees

    2015-09-01

    Full Text Available Efforts to prevent depression have become a key health system priority. Currently, there is a high prevalence of depression among adolescents, and treatment has become costly due to the recurrence patterns of the illness, impairment among patients, and the complex factors needed for a treatment to be effective. Primary care may be the optimal location to identify those at risk by offering an Internet-based preventive intervention to reduce costs and improve outcomes. Few practical interventions have been developed. The models for Internet intervention development that have been put forward focus primarily on the Internet component rather than how the program fits within a broader context. This paper describes the conceptualization for developing technology based preventive models for primary care by integrating the components within a behavioral vaccine framework. CATCH-IT (Competent Adulthood Transition with Cognitive-behavioral, Humanistic and Interpersonal Training has been developed and successfully implemented within various health systems over a period of 14 years among adolescents and young adults aged 13–24.

  15. Explicating an evidence-based, theoretically informed, mobile technology-based system to improve outcomes for people in recovery for alcohol dependence.

    Science.gov (United States)

    Gustafson, David H; Shaw, Bret R; Isham, Andrew; Baker, Timothy; Boyle, Michael G; Levy, Michael

    2011-01-01

    Post-treatment relapse to uncontrolled alcohol use is common. Currently available communication technology can use existing models for relapse prevention to cost-effectively improve long-term relapse prevention. This paper describes: (1) research-based elements of alcohol consumption-related relapse prevention and how they can be encompassed in self-determination theory (SDT) and Marlatt's cognitive behavioral relapse prevention model, (2) how technology could help address the needs of people seeking recovery, (3) a technology-based prototype, organized around sexual transmitted disease and Marlatt's model, and (4) how we are testing a system based on the ideas in this article and related ethical and operational considerations.

  16. Quantitative and qualitative characteristics of grey water for reuse requirements and treatment alternatives: the case of Jordan

    NARCIS (Netherlands)

    Abu-Ghunmi, L.N.A.H.; Zeeman, G.; Lier, van J.B.; Fayyed, M.

    2008-01-01

    The objective of this work is to assess the potentials and requirements for grey water reuse in Jordan. The results revealed that urban, rural and dormitory grey water production rate and concentration of TS, BOD5, COD and pathogens varied between 18-66 L cap(-1) d(-1), 848-1,919, 200-1,056, and 560

  17. Quantitative and qualitative characteristics of grey water for reuse requirements and treatment alternatives: the case of Jordan

    NARCIS (Netherlands)

    Abu-Ghunmi, L.N.A.H.; Zeeman, G.; Lier, van J.B.; Fayyed, M.

    2008-01-01

    The objective of this work is to assess the potentials and requirements for grey water reuse in Jordan. The results revealed that urban, rural and dormitory grey water production rate and concentration of TS, BOD5, COD and pathogens varied between 18-66 L cap(-1) d(-1), 848-1,919, 200-1,056, and

  18. Quantitative and qualitative characteristics of grey water for reuse requirements and treatment alternatives: the case of Jordan

    NARCIS (Netherlands)

    Abu-Ghunmi, L.N.A.H.; Zeeman, G.; Lier, van J.B.; Fayyed, M.

    2008-01-01

    The objective of this work is to assess the potentials and requirements for grey water reuse in Jordan. The results revealed that urban, rural and dormitory grey water production rate and concentration of TS, BOD5, COD and pathogens varied between 18-66 L cap(-1) d(-1), 848-1,919, 200-1,056, and 560

  19. DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation

    Directory of Open Access Journals (Sweden)

    B. Dhakal

    2016-01-01

    Full Text Available Parainfluenza virus (PIV may cause life-threatening pneumonia in allogeneic hematopoietic stem cell transplant (HSCT recipients. Currently, there are no proven effective therapies. We report the use of inhaled DAS181, a novel sialidase fusion protein, for treatment of PIV type 3 pneumonia in two allogeneic hematopoietic SCT recipients with respiratory failure.

  20. APPLICATION OF THE MODEL CERNE FOR THE ESTABLISHMENT OF CRITERIA INCUBATION SELECTION IN TECHNOLOGY BASED BUSINESSES : A STUDY IN INCUBATORS OF TECHNOLOGICAL BASE OF THE COUNTRY

    Directory of Open Access Journals (Sweden)

    Clobert Jefferson Passoni

    2017-03-01

    Full Text Available Business incubators are a great source of encouragement for innovative projects, enabling the development of new technologies, providing infrastructure, advice and support, which are key elements for the success of new business. The technology-based firm incubators (TBFs, which are 154 in Brazil. Each one of them has its own mechanism for the selection of the incubation companies. Because of the different forms of management of incubators, the business model CERNE - Reference Center for Support for New Projects - was created by Anprotec and Sebrae, in order to standardize procedures and promote the increase of chances for success in the incubations. The objective of this study is to propose selection criteria for the incubation, considering CERNE’s five dimensions and aiming to help on the decision-making in the assessment of candidate companies in a TBF incubator. The research was conducted from the public notices of 20 TBF incubators, where 38 selection criteria were identified and classified. Managers of TBF incubators validated 26 criteria by its importance via online questionnaires. As a result, favorable ratings were obtained to 25 of them. Only one criterion differed from the others, with a unfavorable rating.

  1. Old but sexy: Value creation of old technology-based businesses models

    Directory of Open Access Journals (Sweden)

    Oke Christian Beckmann

    2016-12-01

    Full Text Available The purpose of this study is to contribute to a better understanding of the strategic and organisational con gurations that companies can use to generate value with product-market systems and their busi- ness models that have been dominant in the past but forced back into niche positions by innovation. The former dominant music format vinyl was rapidly substituted after the introduction of digital music. However, still nowadays some customers use and buy old technology-based products – vinyl sales boom again since 2007. Due to the two-sided nature of the market, customers have to get access to complementary goods. We are thus interested in technologies which have been outdated by the emergence of new technologies. The originality lies in the combination of the two areas: business models and old technologies. Furthermore, vinyl is an example not analysed in depth by scholars so far. We approached this by undertaking an in-depth literature review to generate hypotheses regarding the value-adding activities of old-technology based businesses as a basis for further research in this area. In addition the paper gives insights into the constellations to be expected over time for old technology-based businesses models in platform markets. We here focus on a neglected topic in the strategy literature which, however, bears relevance for many businesses locked into product-market systems which make it hard for them to (completely switch to a new technology emerging in the market. It is especially valuable to describe the consequences in a systematic fashion.

  2. The Impact of Technology-Based Interventions on Informal Caregivers of Stroke Survivors: A Systematic Review.

    Science.gov (United States)

    Aldehaim, Abdulkarim Yousef; Alotaibi, Faisal F; Uphold, Constance R; Dang, Stuti

    2016-03-01

    This article is a systematic review of the impact of technology-based intervention on outcomes related to care providers for those who survived a stroke. Literature was identified in the PubMed, PsycINFO, Scopus, and Cochrane databases for evidence on technology-based interventions for stroke survivors' caregivers. The search was restricted for all English-language articles from 1970 to February 2015 that implied technology-based interventions. This review included studies that measured the impact of these types of approaches on one or more of the following: depression and any of the following-problem-solving ability, burden, health status, social support, preparedness, and healthcare utilization by care recipient-as secondary outcomes. Telephone or face-to-face counseling sessions were not of interest for this review. The search strategy yielded five studies that met inclusion criteria: two randomized clinical trials and three pilot/preliminary studies, with diverse approaches and designs. Four studies have assessed the primary outcome, two of which reported significant decreases in caregivers' depressive symptoms. Two studies had measured each of the following outcomes-burden, problem-solving ability, health status, and social support-and they revealed no significant differences following the intervention. Only one study assessed caregivers' preparedness and showed improved posttest scores. Healthcare services use by the care recipient was assessed by one study, and the results indicated significant reduction in emergency department visits and hospital re-admissions. Despite various study designs and small sample sizes, available data suggest that an intervention that incorporates a theoretical-based model and is designed to target caregivers as early as possible is a promising strategy. Furthermore, there is a need to incorporate a cost-benefit analysis in future studies.

  3. Financial Management Competence of Founding Teams and Growth of New Technology-Based Firms

    DEFF Research Database (Denmark)

    Brinckmann, Jan; Gemuenden, Hans Georg; Salomo, Søren

    2009-01-01

    This article draws on the resource-based view to analyze the role founding teams' financial management competencies play for firm growth. Prior research stressed the importance of acquiring external financial resources. In this study, we broaden the understanding of financial management in new...... firms. We explore the relevance of strategic financial planning competence, external financing competence, competence in financing from cash flow, and controlling competence of entrepreneurial teams for the growth of new technology-based firms. A total of 212 founding teams provided self...

  4. Usefulness of a detector inlet overpressure and stream splitting in FIA systems to deal with food sample pre-treatment requirements. Application to wine analysis

    OpenAIRE

    Lima, José L. F. C.; Rangel,António O. S. S.

    1991-01-01

    The use of stream splitting to obtain high sampling rate flow injection analysis (FIA) large dispersion manifolds to deal with pre-treatment requirements in the analysis of food components with a high concentration is described. This procedure is illustrated in the FIA determination of calcium using an atomic absorption detector and in the colorimetric determination of phosphate in wines. These manifolds proved to be an advantageous alternative to those including mixing chambers and diluters,...

  5. Interaction between pre-treatment of dyeing and finishing and china standards requirements%印染前处理与中国标准要求

    Institute of Scientific and Technical Information of China (English)

    李建军; 董瑛

    2015-01-01

    The current standard requirements exert different effects in pre-treatment of dyeing and finishing which include mandatory standard, product standard, organic product standard, eco-textile standard, printed and dyed fabric standard and color fastness in wet processstandard. While the pre-treatment processes and technologies were controlled by these standards. The impact of pre-treatment on the standard of GB 18401, GB/T 19630, GB/T 18885, product standards and some requirements of color fastness in wet process were analyzed. The main technical points in pretreatment meet the requirements of the standard wasindicated.%印染前处理对我国现行的部分强制标准、产品标准、有机产品标准、生态纺织品标准、印染布标准和湿处理色牢度标准要求会有不同影响,这些标准也左右着印染加工的前处理工艺和技术。分析了前处理对GB 18401、GB/T 19630、GB/T 18885、部分产品标准及部分湿处理色牢度的相关影响,指出了满足标准要求的前处理技术要点。

  6. Towards personalised management of atherosclerosis via computational models in vascular clinics: technology based on patient-specific simulation approach.

    Science.gov (United States)

    Díaz-Zuccarini, Vanessa; Di Tomaso, Giulia; Agu, Obiekezie; Pichardo-Almarza, Cesar

    2014-01-01

    The development of a new technology based on patient-specific modelling for personalised healthcare in the case of atherosclerosis is presented. Atherosclerosis is the main cause of death in the world and it has become a burden on clinical services as it manifests itself in many diverse forms, such as coronary artery disease, cerebrovascular disease/stroke and peripheral arterial disease. It is also a multifactorial, chronic and systemic process that lasts for a lifetime, putting enormous financial and clinical pressure on national health systems. In this Letter, the postulate is that the development of new technologies for healthcare using computer simulations can, in the future, be developed as in-silico management and support systems. These new technologies will be based on predictive models (including the integration of observations, theories and predictions across a range of temporal and spatial scales, scientific disciplines, key risk factors and anatomical sub-systems) combined with digital patient data and visualisation tools. Although the problem is extremely complex, a simulation workflow and an exemplar application of this type of technology for clinical use is presented, which is currently being developed by a multidisciplinary team following the requirements and constraints of the Vascular Service Unit at the University College Hospital, London.

  7. Treatment

    National Research Council Canada - National Science Library

    Safaa M. Raghab; Ahmed M. Abd El Meguid; Hala A. Hegazi

    2013-01-01

    .... This paper presents the results of the analyses of leachate treatment from the solid waste landfill located in Borg El Arab landfill in Alexandria using an aerobic treatment process which was applied...

  8. A world of hurt: failure to achieve treatment goals in patients with gout requires a paradigm shift.

    Science.gov (United States)

    Khanna, Puja; Khanna, Dinesh; Storgard, Chris; Baumgartner, Scott; Morlock, Robert

    2016-01-01

    Gout continues to be underdiagnosed and poorly managed despite the potential for cure. US and European management guidelines recommend treating to target serum urate (sUA) levels of gout management in the United States by describing the characteristics of a large patient population treated in primary care and rheumatology settings. A retrospective chart audit, conducted among 124 primary care physicians and 125 rheumatologists, included 1245 patients with gout. Physicians completed structured case report forms capturing 12 months of sUA laboratory values, flare counts, comorbidities, types and doses of treatment, treatment duration, diagnosis date, physician specialty and socio-demographic factors. Focusing on the xanthine oxidase inhibitors (n = 858), descriptive statistics and multivariate models characterized relationships between patient characteristics, disease control, and treatment. Only 83 (11%) patients achieved disease control, defined as a 12-month average sUA ≤6 mg/dL, no flares, and no tophi. Patients with greatest disease severity (defined as sUA >6 mg/dL, ≥2 flares per year, and tophi) were more likely to have kidney disease and other comorbidities. In a multivariate model, predictors of more severe gout were rheumatologist (vs primary care) management, febuxostat (vs allopurinol) use and presence of comorbid conditions. Our findings confirm the inadequacy of gout management in the real-world setting. Regular monitoring, including sUA measurement as recommended in guidelines, is important to assess gout control. Our analyses also demonstrate that patients with more severe gout are more likely to have comorbid conditions, be treated by a specialist and use newer therapies.

  9. Microfluidic interface technology based on stereolithography for glass-based lab-on-a-chips.

    Science.gov (United States)

    Han, Song-I; Han, Ki-Ho

    2013-01-01

    As lab-on-a-chips are developed for on-chip integrated microfluidic systems with multiple functions, the development of microfluidic interface (MFI) technology to enable integration of complex microfluidic systems becomes increasingly important and faces many technical difficulties. Such difficulties include the need for more complex structures, the possibility of biological or chemical cross-contamination between functional compartments, and the possible need for individual compartments fabricated from different substrate materials. This chapter introduces MFI technology, based on rapid stereolithography, for a glass-based miniaturized genetic sample preparation system, as an example of a complex lab-on-a-chip that could include functional elements such as; solid-phase DNA extraction, polymerase chain reaction, and capillary electrophoresis. To enable the integration of a complex lab-on-a-chip system in a single chip, MFI technology based on stereolithography provides a simple method for realizing complex arrangements of one-step plug-in microfluidic interconnects, integrated microvalves for microfluidic control, and optical windows for on-chip optical processes.

  10. Efficacy of technology-based interventions to increase the use of hearing protections among adolescent farmworkers.

    Science.gov (United States)

    Khan, Khalid M; Evans, Sydney S; Bielko, Sylvanna L; Rohlman, Diane S

    2017-09-18

    Adolescent farmworkers are exposed to loud noise during farm activities. We present a prospective study that evaluated the efficacy of low-cost, technology-based intervention approaches in high schools to enhance the use of hearing protection among adolescent farmworkers. Six high schools in Iowa that agreed to participate in the study were divided into three equal groups through cluster-randomisation with each group receiving one of the three formats of hearing protection intervention: (a) classroom training, (b) classroom training coupled with smartphone app training and (c) computer training. Participants completed baseline (pre-training) and six-week post-intervention surveys for assessing hearing protection knowledge, attitudes and behaviour. Seventy participants from six schools were initially enrolled but 50 completed both pre- and post-intervention surveys. In most cases, all three groups showed significant improvement in hearing protection knowledge, attitude and frequency of use from pre- to post-intervention. However, changes between groups were statistically non-significant. Although all three formats led to improvements on hearing protection knowledge, attitude and behaviour, the findings of the study, perhaps due to the small sample size, did not allow us to detect whether technology-based hearing protection interventions were more effective than the traditional face-to-face training for adolescent farmworkers.

  11. Remission of CVB3-induced myocarditis with Astragaloside IV treatment requires A20 (TNFAIP3) up-regulation.

    Science.gov (United States)

    Gui, Jun; Chen, Ruizhen; Xu, Wei; Xiong, Sidong

    2015-04-01

    Viral myocarditis (VMC) most prevalently caused by coxsackievirus B3 (CVB3) infection is characterized by severe cardiac inflammation. Therapeutic options for the disease are still limited. Astragaloside IV (AST-IV), a purified small molecular saponin (C41 H68 O14 , MW 784), is the main active component of Chinese medical herb Astragalus which has been empirically prescribed for the treatment of heart dysfunction for centuries. In this study, we investigated the effect of AST-IV on CVB3-induced myocarditis and explored its possible mechanism involved. The results showed that AST-IV administration alleviated the severity of myocarditis and attenuated cardiac inflammation, which was mediated by inhibition of nuclear factor-kappaB (NF-κB) signalling. Importantly, we further identified that the inhibitory effect of AST-IV on NF-κB signalling was through increasing A20 (TNFAIP3) expression. Moreover, we validated that A20 was critical for the therapeutic efficacy of AST-IV on CVB3-induced myocarditis. Finally, we revealed that AST-IV enhanced A20 expression at post-transcriptional level by stabilization of mRNA. Our findings uncover a previously unknown mechanism for AST-IV in the treatment of VMC because of modulating inflammatory response via increasing A20 expression, which provide a potential target for screening new drugs and are helpful for optimization of the therapeutic strategies for VMC.

  12. Spinal epidural abscess penetrating into retroperitoneal space in patient with diabetes mellitus type 2: early diagnosis and treatment requirement.

    Science.gov (United States)

    Grabysa, Radosław; Moczulska, Beata

    2008-01-01

    Spinal epidural abscess (SEA) is a rare condition with very serious prognosis. Predisposing factors for SEA include bacterial infections, immunocompromised states such as diabetes mellitus, intravenous drug abuse, alcoholism, AIDS, as well as spinal surgery and modern techniques of epidural anesthesia. The most common causative agent for SEA is Staphylococcus aureus. The typical clinical signs of SEA are back pain, fever and neurologic dysficit. Magnetic resonance (MR) of the spine and vertebral column is the best imaging diagnostic method in suspected cases. Emergency surgical decompression combined with intravenous antibiotics is the therapeutic method of choice. Conservative treatment may be appropriate in selected patients. Unless the typical presentation of SEA correct diagnosis of this illness is often overlooked and not considered initially. It delays suitable management and leads to poor outcome. We report a classic case of SEA in a woman with a history of diabetes mellitus.

  13. Participatory Research as One Piece of the Puzzle: A Systematic Review of Consumer Involvement in Design of Technology-Based Youth Mental Health and Well-Being Interventions

    Science.gov (United States)

    Lawn, Sharon; Venning, Anthony; Winsall, Megan; Jones, Gabrielle M; Wyld, Kaisha; Damarell, Raechel A; Antezana, Gaston; Schrader, Geoffrey; Smith, David; Collin, Philippa; Bidargaddi, Niranjan

    2015-01-01

    Background Despite the potential of technology-based mental health interventions for young people, limited uptake and/or adherence is a significant challenge. It is thought that involving young people in the development and delivery of services designed for them leads to better engagement. Further research is required to understand the role of participatory approaches in design of technology-based mental health and well-being interventions for youth. Objective To investigate consumer involvement processes and associated outcomes from studies using participatory methods in development of technology-based mental health and well-being interventions for youth. Methods Fifteen electronic databases, using both resource-specific subject headings and text words, were searched describing 2 broad concepts-participatory research and mental health/illness. Grey literature was accessed via Google Advanced search, and relevant conference Web sites and reference lists were also searched. A first screening of titles/abstracts eliminated irrelevant citations and documents. The remaining citations were screened by a second reviewer. Full text articles were double screened. All projects employing participatory research processes in development and/or design of (ICT/digital) technology-based youth mental health and well-being interventions were included. No date restrictions were applied; English language only. Data on consumer involvement, research and design process, and outcomes were extracted via framework analysis. Results A total of 6210 studies were reviewed, 38 full articles retrieved, and 17 included in this study. It was found that consumer participation was predominantly consultative and consumerist in nature and involved design specification and intervention development, and usability/pilot testing. Sustainable participation was difficult to achieve. Projects reported clear dichotomies around designer/researcher and consumer assumptions of effective and acceptable

  14. Participatory Research as One Piece of the Puzzle: A Systematic Review of Consumer Involvement in Design of Technology-Based Youth Mental Health and Well-Being Interventions.

    Science.gov (United States)

    Orlowski, Simone Kate; Lawn, Sharon; Venning, Anthony; Winsall, Megan; Jones, Gabrielle M; Wyld, Kaisha; Damarell, Raechel A; Antezana, Gaston; Schrader, Geoffrey; Smith, David; Collin, Philippa; Bidargaddi, Niranjan

    2015-07-09

    Despite the potential of technology-based mental health interventions for young people, limited uptake and/or adherence is a significant challenge. It is thought that involving young people in the development and delivery of services designed for them leads to better engagement. Further research is required to understand the role of participatory approaches in design of technology-based mental health and well-being interventions for youth. To investigate consumer involvement processes and associated outcomes from studies using participatory methods in development of technology-based mental health and well-being interventions for youth. Fifteen electronic databases, using both resource-specific subject headings and text words, were searched describing 2 broad concepts-participatory research and mental health/illness. Grey literature was accessed via Google Advanced search, and relevant conference Web sites and reference lists were also searched. A first screening of titles/abstracts eliminated irrelevant citations and documents. The remaining citations were screened by a second reviewer. Full text articles were double screened. All projects employing participatory research processes in development and/or design of (ICT/digital) technology-based youth mental health and well-being interventions were included. No date restrictions were applied; English language only. Data on consumer involvement, research and design process, and outcomes were extracted via framework analysis. A total of 6210 studies were reviewed, 38 full articles retrieved, and 17 included in this study. It was found that consumer participation was predominantly consultative and consumerist in nature and involved design specification and intervention development, and usability/pilot testing. Sustainable participation was difficult to achieve. Projects reported clear dichotomies around designer/researcher and consumer assumptions of effective and acceptable interventions. It was not possible to

  15. [Temporal perspective and other psychological factors making it difficult to adapt to requirements of treatment in chronic dialysis patients].

    Science.gov (United States)

    Zawadzka, Barbara; Byrczek, Magdalena; Zawadzka, Sara

    2014-01-01

    The study analyzed the relationship between temporal perspective, selected personal resources, and unhealthy behavior, manifesting in problems with adherence to fluid intake restrictions, in chronic.hemodialyzis patients. The authors tried to answer the question whether there is temporal perspective and other psychological factors increasing the risk of non-adaptive behaviors. Sixty-one patients, aged 23-81 years (m = 59; SD = 13,9) on chronic hemodialysis at the Department of Nephrology University Hospital were qualified to the study. The study group consisted of 30 patients with poorer fluid regimen adherence and 31 con- trols, who maintained fluid regimen. The patients were qualified on the bases of the average interdialysis weight gains measured nine times during three weeks. The following research tools were used: P. Zimbardo and J. Boyd ZTPI test; P.T. Costa and R.R. McCrae NEO-FFI Inventory; J. Strelau Temperament Inventory, R. Schwarzer GSES; M. F. Scheier; C. S. Carver and M. W. Bridges LOT-R; M. Watson and S. Greer CECS; BJ. Felton, TA. Revenson, GA. Hinrichsen AIS. Difficulties in adapting to the fluid intake restrictions are significantly associated with temporal orientation towards negative aspects of the present and the past. Non-adaptive health behaviors are typical for patients with temperamental lack of balance between agitation and inhibition processes and are characterized by high agreeableness and low conscientious- ness. The association between excessive anger control and the risk of non-adherence medical recommendations. Time perception and other personality factors form mechanisms regulating health behaviors in chronically treatment patients.

  16. Temporal perspective and other psychological factors making it difficult to adapt to requirements of treatment in chronic dialysis patients

    Directory of Open Access Journals (Sweden)

    Zawadzka, Barbara

    2014-10-01

    Full Text Available Aim. The study analyzed the relationship between temporal perspective, selected personal resources, and unhealthy behavior, manifesting in problems with adherence to fluid intake restrictions, in chronic hemodialyzis patients. The authors tried to answer the question whether there is temporal perspective and other psychological factors increasing the risk of non-adaptive behaviors. Methods. Sixty-one patients, aged 23–81 years (M = 59; SD = 13,9 on chronic hemodialysis at the Department of Nephrology University Hospital were qualified to the study. The study group consisted of 30 patients with poorer fluid regimen adherence and 31 controls, who maintained fluid regimen. The patients were qualified on the bases of the average interdialysis weight gains measured nine times during three weeks. The following research tools were used: P. Zimbardo and J. Boyd ZTPI test; P.T. Costa and R.R. McCrae NEO-FFI Inventory; J. Strelau Temperament Inventory, R. Schwarzer GSES; M. F. Scheier; C. S. Carver and M. W. Bridges LOT-R; M. Watson and S. Greer CECS; BJ. Felton, TA. Revenson, GA. Hinrichsen AIS. Results. Difficulties in adapting to the fluid intake restrictions are significantly associated with temporal orientation towards negative aspects of the present and the past. Non-adaptive health behaviors are typical for patients with temperamental lack of balance between agitation and inhibition processes and are characterized by high agreeableness and low conscientiousness. The association between excessive anger control and the risk of non-adherence medical recommendations. Conclusions. Time perception and other personality factors form mechanisms regulating health behaviors in chronically treatment patients.

  17. Bringing Technology to Students’ Proximity: A Sociocultural Account of Technology-Based Learning Projects

    Directory of Open Access Journals (Sweden)

    Evode Mukama

    2014-12-01

    Full Text Available This paper depicts a study carried out in Rwanda concerning university students who participated in a contest to produce short documentary films. The purpose of this research is to conceptualize these kinds of technology-based learning projects (TBLPs through a sociocultural perspective. The methodology included focus-group discussions and field notes to collect empirical data. The findings reveal that the more educational technologies capture objects of learning positioned in the students’ sociocultural proximity, the more focused the learners’ attention is on these objects. The study shows also that a change in learning projects may depend to a large extent on whether the technology relates to the students’ sociocultural proximity, that is, taking into consideration students’ physical, cultural, and contextual real world. The study recommends a community of learning/inquiry embedded in a collaborative, problem-solving dynamic involving cognitive support from peers, teachers, external specialists, and the wider community.

  18. Inner structure detection by optical tomography technology based on feedback of microchip Nd:YAG lasers.

    Science.gov (United States)

    Xu, Chunxin; Zhang, Shulian; Tan, Yidong; Zhao, Shijie

    2013-05-20

    We describe a new optical tomography technology based on feedback of microchip Nd:YAG lasers. In the case of feedback light frequency-shifted, light can be magnified by a fact of 10(6) in the Nd:YAG microchip lasers, which makes it possible to realize optical tomography with a greater depth than current optical tomography. The results of the measuring and imaging of kinds of samples are presented, which demonstrate the feasibility and potential of this approach in the inner structure detection. The system has a lateral resolution of ~1 μm, a vertical resolution of 15 μm and a longitudinal scanning range of over 10mm.

  19. Study on 8DPSK of multi-phase modulation technology based on CSRZ

    Institute of Scientific and Technical Information of China (English)

    XU Heng-ying; NIU Hui-juan; ZHANG Min; WANG Fang; BAI Cheng-lin; ZHANG Xiao-guang

    2011-01-01

    A new modulation format in optical fiber communication system, the eight differential phase shift keying (8DPSK) of multi-phase modulation technology based on carrier-suppressed return-to-zero (CSRZ) is proposed in this paper. The formulae of CSRZ-8DPSK modem methods are derived theoretically and the methods are demonstrated. Spectra based on CSRZ and CSRZ-8DPSK modulation methods and their eye diagrams by simulation with MATLAB are obtained. The results show that the CSRZ-8DPSK modulation methods have narrower spectra with higher efficiency. The performance of eye diagrams is also much satisfactory after demodulation, suggesting some possible applications of the methods in the next generation of optical fiber communications.

  20. The application of confocal technology based on polycapillary X-ray optics in surface topography

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Guangcui, E-mail: zgcshirley@yahoo.cn [The Key Laboratory of Beam Technology and Material Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Sun, Tianxi; Liu, Zhiguo; Yuan, Hao; Li, Yude; Liu, Hehe; Zhao, Weigang; Zhang, Ruixia; Min, Qin; Peng, Song [The Key Laboratory of Beam Technology and Material Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China)

    2013-09-01

    A confocal micro-X-ray fluorescence (MXRF) technology based on polycapillary X-ray optics was proposed for determining surface topography. This confocal topography method involves elemental sensitivity and can be used to classify the objects according to their elemental composition while obtaining their surface topography. To improve the spatial resolution of this confocal topography technology, the center of the confocal micro-volume was overlapped with the output focal spot of the polycapillary X-ray, focusing the lens in the excitation channel. The input focal spot of the X-ray lens parallel to the detection channel was used to determine the surface position of the sample. The corresponding surface adaptive algorithm was designed to obtain the surface topography. The surface topography of a ceramic chip was obtained. This confocal MXRF surface topography method could find application in the materials sciences.

  1. The application and development of radiography technology based on x-ray

    Science.gov (United States)

    Chen, Hao; Xu, Zhou; Li, Ming

    2009-07-01

    Modern Radiography technology was combined with radiation physics and modern imaging processing, which was an important branch of information obtainment and processing. We can get the inside information of the object, by the X ray's attenuation when the ray penetrated the object, and depending on the computer's fast processing, we can see the slice imaging of the object. Computerized Tomography, Computerized Laminography, and Digital Radiography were important parts in Radiography. The institute of applied electronics, CAEP in the research of intense radiation had developed several advanced radiation sources and some advanced radiography imaging systems, for example, S-band small spot linear accelerator, full solid state modulator, C-band linear accelerator, high energy Tera-hertz radiation source and CT technology based on cone beam, DR technology, CL Technology etc. Such imaging systems had been applied in industrial NDT/NDE, security check, medical diagnosis, petroleum and gas pipeline inspection system etc.

  2. PENGARUH AKSES PELAYANAN KESEHATAN, PERFORMED TREAMENT INDEX/PTI REQUIREMENT TREATMENT INDEX/RTI, TERHADAP PERILAKU ORAL HYGIENE

    Directory of Open Access Journals (Sweden)

    Niniek L. Pratiwi

    2012-11-01

    affordability cross-subsidies required to increase purchasing power of a toothpaste containing fluoride levels and toothbrushes that can reach people, especially the poor. Key words: PTI, RTI, Perilaku Oral Hygiene, sosial ekonomi, akses pelayanan kesehatan

  3. Optimising conventional treatment of domestic waste water: quality, required surface area, solid waste minimisation and biogas production for medium and small-scale applications

    CSIR Research Space (South Africa)

    Szewczuk, S

    2010-09-01

    Full Text Available .kashan.co.za] Optimising conventional treatment of domestic waste water: quality, required surface area, solid waste minimisation and biogas production for medium and small-scale applications S SZEWCZUK, SP ROUX, M LINDEQUE, J GERMANIS CSIR, PO Box 395, Pretoria, 0001...) and the methane-rich gas yield is used for heating the Ad reactor itself. Increased efficiency due to technological progress can increase the gas yield, reduce the reactor dependency on biogas for heating and allow more efficient use of the biogas...

  4. SIGUEME: Technology-based intervention for low-functioning autism to train skills to work with visual signifiers and concepts.

    Science.gov (United States)

    Vélez-Coto, María; Rodríguez-Fórtiz, María José; Rodriguez-Almendros, María Luisa; Cabrera-Cuevas, Marcelino; Rodríguez-Domínguez, Carlos; Ruiz-López, Tomás; Burgos-Pulido, Ángeles; Garrido-Jiménez, Inmaculada; Martos-Pérez, Juan

    2017-05-01

    People with low-functioning ASD and other disabilities often find it difficult to understand the symbols traditionally used in educational materials during the learning process. Technology-based interventions are becoming increasingly common, helping children with cognitive disabilities to perform academic tasks and improve their abilities and knowledge. Such children often find it difficult to perform certain tasks contained in educational materials since they lack necessary skills such as abstract reasoning. In order to help these children, the authors designed and created SIGUEME to train attention and the perceptual and visual cognitive skills required to work with and understand graphic materials and objects. A pre-test/post-test design was implemented to test SIGUEME. Seventy-four children with low-functioning ASD (age=13.47, SD=8.74) were trained with SIGUEME over twenty-five sessions and compared with twenty-eight children (age=12.61, SD=2.85) who had not received any intervention. There was a statistically significant improvement in the experimental group in Attention (W=-5.497, p<0.001). There was also a significant change in Association and Categorization (W=2.721, p=0.007) and Interaction (W=-3.287, p=0.001). SIGUEME is an effective tool for improving attention, categorization and interaction in low-functioning children with ASD. It is also a useful and powerful instrument for teachers, parents and educators by increasing the child's motivation and autonomy. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Rapid detection of abrin in foods with an up-converting phosphor technology-based lateral flow assay

    Science.gov (United States)

    Liu, Xiao; Zhao, Yong; Sun, Chongyun; Wang, Xiaochen; Wang, Xinrui; Zhang, Pingping; Qiu, Jingfu; Yang, Ruifu; Zhou, Lei

    2016-01-01

    Abrin is a natural plant toxin found in the seeds of Abrus precatorius. It may be used for food poisoning or bioterrorism, seriously endangering public health. In this study, a reliable method for the rapid detection of abrin in foods was developed, based on an up-converting phosphor technology-based lateral flow assay (abrin-UPT-LFA). Nine high-affinity monoclonal antibodies (mAbs) against abrin were prepared, and the optimum mAbs (mAb-6F4 and mAb-10E11) were selected for use in the assay in double-antibody-sandwich mode. The assay was confirmed to be specific for abrin, with a detection sensitivity of 0.1 ng mL−1 for standard abrin solutions. Good linearity was observed for abrin quantitation from 0.1 to 1000 ng mL−1 (r = 0.9983). During the analysis of various abrin-spiked food samples, the assay showed strong sample tolerance and a satisfactory limit of detection for abrin (0.5–10 ng g−1 for solid and powdered samples; 0.30–0.43 ng mL−1 for liquid samples). The analysis of suspected food samples, from sample treatment to result feed-back, could be completed by non-professionals within 20 min. Therefore, the abrin-UPT-LFA is a rapid, sensitive, and reliable method for the on-site detection of abrin in foods. PMID:27703269

  6. Clinical features and hyperplastic patterns of parathyroid glands in hemodialysis patients with advanced secondary hyperparathyroidism refractory to maxacalcitol treatment and required parathyroidectomy.

    Science.gov (United States)

    Tominaga, Yoshihiro; Matsuoka, Susumu; Sato, Tetsuhiko; Uno, Nobuyuki; Goto, Norihiko; Katayama, Akio; Haba, Toshihito

    2007-08-01

    We have previously suggested that when parathyroid glands progress to nodular hyperplasia, secondary hyperparathyroidism (2HPT) may be refractory to medical treatments, including treatment with Maxacalcitol (OCT). In the present study we evaluated the clinical features and hyperplastic patterns of parathyroid glands in patients who underwent parathyroidectomy (PTx) after being withdrawn from OCT. One hundred and eighty-seven advanced 2HPT patients who had been withdrawn from OCT and required PTx were enrolled. At the start of OCT treatment, the patients had a mean age of 55.3 years and had been receiving hemodialysis (HD) for a mean period of 149 months. At the start of OCT treatment and at PTx, the mean intact PTH (i-PTH) levels were 772.8 +/- 446.0 and 855.5 +/- 420.5 pg/mL, respectively. The main reasons for withdrawal of OCT treatment were persistently high PTH (n = 148), hypercalcemia (n = 79), hyperphosphatemia (n = 65), and progressive symptoms (n = 60). We classified the parathyroid glands by hyperplastic pattern into four categories: diffuse hyperplastic gland (D), early nodularity in diffuse hyperplastic gland (EN), nodular hyperplastic gland (N), and single nodular gland (SN). The mean total excised gland weight was 2592.6 mg. Out of a total of 706 glands, 118 were classified as D, 66 as EN, 436 as N, and 86 as SN. All patients had at least one nodular hyperplastic gland or single nodular gland. The mean number of nodular hyperplastic glands and/or single nodular glands was 2.9. All hemodialysis patients with advanced OCT-refractory 2HPT who underwent PTx had at least one nodular hyperplastic gland or single nodular gland.

  7. DESIGNING INSTRUCTION FOR THE TRADITIONAL, ADULT, AND DISTANCE LEARNER: A New Engine for Technology-Based Teaching

    Directory of Open Access Journals (Sweden)

    Lawrence A. Tomei

    2011-10-01

    Full Text Available Adult students demand a wider variety of instructional strategies that encompass real-world, interactive, cooperative, and discovery learning experiences.Designing Instruction for the Traditional, Adult, and Distance Learner: A New Engine for Technology-Based Teaching explores how technology impacts the process of devising instructional plans as well as learning itself in adult students. Containing research from leading international experts, this publication proposes realistic and accurate archetypes to assist educators in incorporating state-of-the-art technologies into online instruction.This text proposes a new paradigm for designing, developing, implementing, and assessed technology-based instruction. It addresses three target populations of today's learner: traditional, adult, and distance education. The text proposes a new model of instructional system design (ISD for developing effective technology-based education that involves a five-step process focusing on the learner, learning theories, resources, delivery modalities, and outcomes.

  8. Implications of the minimal clinically important difference for health-related quality-of-life outcomes: a comparison of sample size requirements for an incontinence treatment trial.

    Science.gov (United States)

    Halme, Alex S; Fritel, Xavier; Benedetti, Andrea; Eng, Ken; Tannenbaum, Cara

    2015-03-01

    Sample size calculations for treatment trials that aim to assess health-related quality-of-life (HRQOL) outcomes are often difficult to perform. Researchers must select a target minimal clinically important difference (MCID) in HRQOL for the trial, estimate the effect size of the intervention, and then consider the responsiveness of different HRQOL measures for detecting improvements. Generic preference-based HRQOL measures are usually less sensitive to gains in HRQOL than are disease-specific measures, but are nonetheless recommended to quantify an impact on HRQOL that can be translated into quality-adjusted life-years during cost-effectiveness analyses. Mapping disease-specific measures onto generic measures is a proposed method for yielding more efficient sample size requirements while retaining the ability to generate utility weights for cost-effectiveness analyses. This study sought to test this mapping strategy to calculate and compare the effect on sample size of three different methods. Three different methods were used for determining an MCID in HRQOL in patients with incontinence: 1) a global rating of improvement, 2) an incontinence-specific HRQOL instrument, and 3) a generic preference-based HRQOL instrument using mapping coefficients. The sample size required to detect a 20% difference in the MCID for the global rating of improvement was 52 per trial arm, 172 per arm for the incontinence-specific HRQOL outcome, and 500 per arm for the generic preference-based HRQOL outcome. We caution that treatment trials of conditions for which improvements are not easy to measure on generic HRQOL instruments will still require significantly greater sample size even when mapping functions are used to try to gain efficiency. Copyright © 2015 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  9. A randomised, double-blind trial comparing ceftobiprole medocaril with ceftriaxone with or without linezolid for the treatment of patients with community-acquired pneumonia requiring hospitalisation.

    Science.gov (United States)

    Nicholson, Susan C; Welte, Tobias; File, Thomas M; Strauss, Richard S; Michiels, Bart; Kaul, Pratibha; Balis, Dainius; Arbit, Deborah; Amsler, Karen; Noel, Gary J

    2012-03-01

    Community-acquired pneumonia (CAP) is a serious infection requiring hospitalisation in 20% of cases. The novel cephalosporin ceftobiprole has microbiological activity against the major bacterial pathogens causing CAP, including Streptococcus pneumoniae, Haemophilus influenzae and Klebsiella pneumoniae, as well as against Staphylococcus aureus, including meticillin-resistant S. aureus (MRSA). This was a multicentre, double-blind study in which 706 patients with CAP severe enough to require hospitalisation were randomised to ceftobiprole or to an expert-recommended course of ceftriaxone ± linezolid (comparator group). Clinical and microbiological outcomes were determined 7-14 days after completion of therapy (test-of-cure visit). For the 469 clinically evaluable patients, cure rates were 86.6% vs. 87.4% for ceftobiprole and comparator, respectively [95% confidence interval (CI) of the difference, -6.9% to 5.3%]; in the intention-to-treat (ITT) analysis of 638 CAP patients, these cure rates were 76.4% vs. 79.3%, respectively (95% CI of the difference, -9.3% to 3.6%). A typical bacterial pathogen was identified in 29% of the ITT population. Microbiological eradication rates in the 144 microbiologically evaluable patients were 88.2% and 90.8% for the respective treatment groups (95% CI of the difference, -12.6% to 7.5%). Both study drugs were well tolerated, with but a minority of patients requiring premature discontinuation due to an adverse event (6% in the ceftobiprole group and 4% in the comparator group). The overall incidence of treatment-related adverse events was higher in the ceftobiprole group, primarily owing to differences in rates of self-limited nausea (7% vs. 2%) and vomiting (5% vs. 2%). In summary, ceftobiprole was non-inferior to the comparator (ceftriaxone ± linezolid) in all clinical and microbiological analyses conducted, suggesting that ceftobiprole has a potential role in treating hospitalised patients with CAP. [ClinicalTrials.gov identifier

  10. GROWTH AND VENTURE CAPITAL INVESTMENT IN TECHNOLOGY-BASED SMALL FIRMS THE CASE OF HUNGARY

    Directory of Open Access Journals (Sweden)

    Becsky Nagy Patricia

    2014-07-01

    Full Text Available Venture capital backed enterprises represent a low proportion of companies, even of innovative ones. The research question was, whether these companies have an important role in innovation and economic growth in Hungary compared to other countries. In the first part of the article I present the theoretical background of technology-based small firms, highlighting the most important models and theories of the economic impact and the special development of innovative technology-oriented small firms. In the second part of the article I present the status of the most important indicators of innovation in connection with entrepreneurship, than I elaborate on the measures of start-ups, mainly the high-tech ones with high-growth potential. I describe the current position of venture capital industry, detailing the venture capital investments, with particular emphasis on classical venture capital investments that points out the number and the amount of venture capital investments financing early stage firms with high-growth potential. At the end I summarize the status of Hungarian technology-based small firms and their possibilities to get financial sources form venture capital investors, with regards to the status and the prospects of the JEREMIE program. In Hungary the number of internationally competitive firms, ready and willing to obtain venture capital, is much lower than in the US or Western European countries. Hungary could take advantage of its competitive edges in some special fields of innovation. The efficiency of information flow would reduce the information gap between the demand and the supply side of the venture capital market and more Hungarian firms could be internationally successful through venture capital financing. The recent years’ policy and special programs like JEREMIE generated more transactions, that helped to inform the entrepreneurs about venture capital and helped to co-invest public resources with private equity more

  11. Green Manufacturing Technology Based on Life Cycle%基于生命周期的绿色制造技术

    Institute of Scientific and Technical Information of China (English)

    吕宏

    2001-01-01

    The new concept of green manufacturing technology based on life cycle according to the requirements for product features in the 21stcentury is put forward in this paper.The background and research method of the green manufacturing technology and the study of clean production,green materials and green products are simply described.%从 21世纪对产品特征的要求出发,提出了基于生命周期的绿色制造技术这一新概念,简述了绿色制造技术产生的背景、研究的方法及清洁生产、绿色材料与绿色产品的研究。

  12. Explicating an Evidence-Based, Theoretically Informed, Mobile Technology-Based System to Improve Outcomes for People in Recovery for Alcohol Dependence

    Science.gov (United States)

    Gustafson, David H.; Isham, Andrew; Baker, Timothy; Boyle, Michael G.; Levy, Michael

    2011-01-01

    Post treatment relapse to uncontrolled alcohol use is common. More cost-effective approaches are needed. We believe currently available communication technology can use existing models for relapse prevention to cost-effectively improve long-term relapse prevention. This paper describes: 1) research-based elements of alcohol related relapse prevention and how they can be encompassed in Self Determination Theory (SDT) and Marlatt’s Cognitive Behavioral Relapse Prevention Model, 2) how technology could help address the needs of people seeking recovery, 3) a technology-based prototype, organized around Self Determination Theory and Marlatt’s model and 4) how we are testing a system based on the ideas in this article and related ethical and operational considerations. PMID:21190410

  13. Market Segmentation in Business Technology Base: The Case of Segmentation of Sparkling

    Directory of Open Access Journals (Sweden)

    Valéria Riscarolli

    2014-08-01

    Full Text Available A common market segmentation premise for products and services rules consumer behavior as the segmentation center piece. Would this be the logic for segmentation used by small technology based companies? In this article we target at determining the principles of market segmentation used by a vitiwinery company, as research object. This company is recognized by its products excellence, either in domestic as well as in the foreign market, among 13 distinct countries. The research method used is a case study, through information from the company’s CEOs and crossed by primary information from observation and formal registries and documents of the company. In this research we look at sparkling wines market segmentation. Main results indicate that the winery studied considers only technological elements as the basis to build a market segment. One may conclude that a market segmentation for this company is based upon technological dominion of sparkling wines production, aligned with a premium-price policy. In the company, directorship believes that as sparkling wines market is still incipient in the country, sparkling wine market segments will form and consolidate after the evolution of consumers tasting preferences, depending on technologies that boost sparkling wines quality. 

  14. Technology-Based Innovations in Child Maltreatment Prevention Programs: Examples from SafeCare®

    Directory of Open Access Journals (Sweden)

    Melissa Cowart-Osborne

    2014-08-01

    Full Text Available Each year, hundreds of thousands of children in the U.S. are victims of child maltreatment. Experts recommend behavioral, skill-based parent training programs as a strategy for the prevention of child abuse and neglect. These programs can be enhanced using innovative technology strategies. This paper presents a brief history of the use of technology in SafeCare®, a home visiting program shown to prevent child neglect and physical abuse, and highlights current work that takes a technology-based hybrid approach to SafeCare delivery. With this unique approach, the provider brings a tablet computer to each session, and the parent interacts with the software to receive psychoeducation and modeling of target skills. The provider and parent then work together to practice the targeted skills until mastery is achieved. Initial findings from ongoing research of both of these strategies indicate that they show potential for improving engagement and use of positive parenting skills for parents and ease of implementation for providers. Future directions for technology enhancements in SafeCare are also presented.

  15. An Analysis of Knowledge Sharing Approaches for Emerging-technology-based Strategic Alliances in Electronic Industry

    Institute of Scientific and Technical Information of China (English)

    LIU Ju; LI Yong-jian

    2006-01-01

    Emerging technologies are now initiating new industries and transforming old ones with tremendous power. They are different games compared with established technologies with distinctive characteristics of knowledge management in knowledge-based and technological-innovation-based competition. How to obtain knowledge advantage and enhance competences by knowledge sharing for emerging-technology-based strategic alliances (ETBSA) is what we concern in this paper. On the basis of our previous work on emerging technologies'distinctive attributes, we counter the wide spread presumption that the primary purpose of strategic alliances is knowledge acquiring by means of learning. We offers new insight into the knowledge sharing approaches of ETBSAs - the knowledge integrating approach by which each member firm integrates its partner's complementary knowledge base into the products and services and maintains its own knowledge specialization at the same time. So that ETBSAs should plan and practice their knowledge sharing strategies from the angle of knowledge integrating rather than knowledge acquiring. A four-dimensional framework is developed to analyze the advantages and disadvantages of these two knowledge sharing approaches. Some cases in electronic industry are introduced to illustrate our point of view.

  16. Understanding adolescent response to a technology-based depression prevention program.

    Science.gov (United States)

    Gladstone, Tracy; Marko-Holguin, Monika; Henry, Jordan; Fogel, Joshua; Diehl, Anne; Van Voorhees, Benjamin W

    2014-01-01

    Guided by the Behavioral Vaccine Theory of prevention, this study uses a no-control group design to examine intervention variables that predict favorable changes in depressive symptoms at 6- to 8-week follow-up in at-risk adolescents who participated in a primary care, Internet-based prevention program. Participants included 83 adolescents from primary care settings ages 14 to 21 (M = 17.5, SD = 2.04), 56.2% female, with 41% non-White. Participants completed self-report measures, met with a physician, and then completed a 14-module Internet intervention targeting the prevention of depression. Linear regression models indicated that several intervention factors (duration on website in days, the strength of the relationship with the physician, perceptions of ease of use, and the perceived relevance of the material presented) were significantly associated with greater reductions in depressive symptoms from baseline to follow-up. Automatic negative thoughts significantly mediated the relation between change in depressive symptoms scores and both duration of use and physician relationship. Several intervention variables predicted favorable changes in depressive symptom scores among adolescents who participated in an Internet-based prevention program, and the strength of two of these variables was mediated by automatic negative thoughts. These findings support the importance of cognitive factors in preventing adolescent depression and suggest that modifiable aspects of technology-based intervention experience and relationships should be considered in optimizing intervention design.

  17. Angiotensin-converting enzyme and angiotensin II receptor subtype 2 genotypes in type 1 diabetes and severe hypoglycaemia requiring emergency treatment: a case cohort study

    DEFF Research Database (Denmark)

    Pedersen-Bjergaard, Ulrik; Nielsen, Søren L; Akram, Kamran

    2009-01-01

    . METHODS: The case cohort study consisted of 108 cases of type 1 diabetic patients with severe hypoglycaemia requiring medical emergency treatment during a 1-year period and 262 consecutive controls without such events. ACE I/D and AT2R 1675G>A genotype distributions were compared between cases......AIMS: In type 1 diabetes, individual susceptibility to severe hypoglycaemia is likely to be influenced by genetic factors. We have previously reported an association of the deletion (D-) allele of the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism and the A...... and controls. RESULTS: The proportion of D-allele carriers was higher amongst cases than controls (83 vs. 73%; P=0.032). In contrast, AT2R genotype distribution was similar in cases and controls. In a multiple regression analysis, D-allele carriage remained a significant risk factor for being a case [odds...

  18. Seeing around a Ball: Complex, Technology-Based Problems in Calculus with Applications in Science and Engineering-Redux

    Science.gov (United States)

    Winkel, Brian

    2008-01-01

    A complex technology-based problem in visualization and computation for students in calculus is presented. Strategies are shown for its solution and the opportunities for students to put together sequences of concepts and skills to build for success are highlighted. The problem itself involves placing an object under water in order to actually see…

  19. The Influence of a Technology-Based Internship on First-Year Teachers' Instructional Decision-Making

    Science.gov (United States)

    Alexander, Curby; Kjellstrom, William

    2014-01-01

    This qualitative study examined the influence of technology-based internships on teachers' instructional decision-making during their first year in the classroom. Field experiences offer preservice teachers opportunities to observe and practice teaching, yet they rarely target technology. Using a case study design, this study explored the…

  20. Assessing the needs of new technology based firms (NTBFs): An investigation among spin-off companies from six European Universities

    NARCIS (Netherlands)

    Kirwan, P.M.; van der Sijde, Peter; Groen, Arend J.

    2006-01-01

    New technology based firms (NTBFs) play a major role in the development and commercialisation of new technologies and the development of national economies. Using an entrepreneurship-in-networks approach, this paper examines the early stages of the development of these companies, i.e. from opportuni

  1. Research Trends in Technology-Based Learning from 2000 to 2009: A Content Analysis of Publications in Selected Journals

    Science.gov (United States)

    Hsu, Yu-Chen; Ho, Hsin Ning Jessie; Tsai, Chin-Chung; Hwang, Gwo-Jen; Chu, Hui-Chun; Wang, Chin-Yeh; Chen, Nian-Shing

    2012-01-01

    This paper provides a content analysis of studies in technology-based learning (TBL) that were published in five Social Sciences Citation Index (SSCI) journals (i.e. "the British Journal of Educational Technology, Computers & Education, Educational Technology Research & Development, Educational Technology & Society, the Journal of Computer…

  2. How Adults Learn from Self-Paced, Technology-Based Corporate Training: New Focus for Learners, New Focus for Designers

    Science.gov (United States)

    Dobrovolny, Jackie

    2006-01-01

    "How" do adults learn from self-paced, technology-based corporate training, which they select based on its relevance to their current employment responsibilities? Specifically, "how" do adults use the following learning strategies: prior experience, reflection, metacognition, conversations, generative learning strategies, and authentic…

  3. The Influence of a Technology-Based Internship on First-Year Teachers' Instructional Decision-Making

    Science.gov (United States)

    Alexander, Curby; Kjellstrom, William

    2014-01-01

    This qualitative study examined the influence of technology-based internships on teachers' instructional decision-making during their first year in the classroom. Field experiences offer preservice teachers opportunities to observe and practice teaching, yet they rarely target technology. Using a case study design, this study explored the…

  4. Higher percentage of in vitro apoptotic cells at time of diagnosis in patients with chronic lymphocytic leukemia indicate earlier treatment requirement: Ten years follow up

    Directory of Open Access Journals (Sweden)

    Kravić-Stevović Tamara

    2014-01-01

    Full Text Available Introduction. Chronic lymphocytic leukemia (CLL has an extremely variable clinical course. Biological reasons for that wide variation in clinical course and survival rates in CLL patients are not fully understood. Objective. The aim of the study was to evaluate the value of spontaneous apoptosis of CLL cells in vitro determined at presentation of disease, in prediction of treatment requirements and evolution of the CLL. Methods. Malignant B cells were isolated from the whole blood of 30 newly diagnosed CLL patients and cultured for 24 hours in RPMI-1640 medium supplemented with 10% of serum obtained from the same CLL patient. Cells were later fixed and processed for embedding in Epon, or cell smears were prepared and stained with TUNEL technique. Results. Ten-year follow-up revealed that patients with lower percentage of cells in apoptosis at presentation of disease had significant longer time treatment initiation (log rank test p0.05. Conclusion. The results of this study emphasize the importance of apoptosis of CLL cells at the time of the initial diagnosis in pathobiology of this disease. [Projekat Ministarstva nauke Republike Srbije, br. 41025

  5. Chloroquine could be used for the treatment of filoviral infections and other viral infections that emerge or emerged from viruses requiring an acidic pH for infectivity.

    Science.gov (United States)

    Akpovwa, Hephzibah

    2016-06-01

    Viruses from the Filoviridae family, as many other virus families, require an acidic pH for successful infection and are therefore susceptible to the actions of 4-aminoquinolines, such as chloroquine. Although the mechanisms of action of chloroquine clearly indicate that it might inhibit filoviral infections, several clinical trials that attempted to use chloroquine in the treatment of other acute viral infections - including dengue and influenza A and B - caused by low pH-dependent viruses, have reported that chloroquine had no clinical efficacy, and these results demoted chloroquine from the potential treatments for other virus families requiring low pH for infectivity. The present review is aimed at investigating whether chloroquine could combat the present Ebola virus epidemic, and also at exploring the main reasons for the reported lack of efficacy. Literature was sourced from PubMed, Scopus, Google Scholar, reference list of articles and textbooks - Fields Virology (Volumes 1and 2), the cytokine handbook, Pharmacology in Medicine: Principles and Practice, and hydroxychloroquine and chloroquine retinopathy. The present analysis concludes that (1) chloroquine might find a place in the treatment of Ebola, either as a monotherapy or in combination therapies; (2) the ineffectiveness of chloroquine, or its analogue, hydroxychloroquine, at treating infections from low pH-dependent viruses is a result of the failure to attain and sustain a steady state concentration sufficient to increase and keep the pH of the acidic organelles to approximately neutral levels; (3) to successfully treat filoviral infections - or other viral infections that emerge or emerged from low pH-dependent viruses - a steady state chloroquine plasma concentration of at least 1 µg/mL(~3.125 μM/L) or a whole blood concentration of 16 μM/L must be achieved and be sustained until the patients' viraemia becomes undetectable. These concentrations, however, do not rule out the efficacy of

  6. Research of maneuvering target prediction and tracking technology based on IMM algorithm

    Science.gov (United States)

    Cao, Zheng; Mao, Yao; Deng, Chao; Liu, Qiong; Chen, Jing

    2016-09-01

    Maneuvering target prediction and tracking technology is widely used in both military and civilian applications, the study of those technologies is all along the hotspot and difficulty. In the Electro-Optical acquisition-tracking-pointing system (ATP), the primary traditional maneuvering targets are ballistic target, large aircraft and other big targets. Those targets have the features of fast velocity and a strong regular trajectory and Kalman Filtering and polynomial fitting have good effects when they are used to track those targets. In recent years, the small unmanned aerial vehicles developed rapidly for they are small, nimble and simple operation. The small unmanned aerial vehicles have strong maneuverability in the observation system of ATP although they are close-in, slow and small targets. Moreover, those vehicles are under the manual operation, therefore, the acceleration of them changes greatly and they move erratically. So the prediction and tracking precision is low when traditional algorithms are used to track the maneuvering fly of those targets, such as speeding up, turning, climbing and so on. The interacting multiple model algorithm (IMM) use multiple models to match target real movement trajectory, there are interactions between each model. The IMM algorithm can switch model based on a Markov chain to adapt to the change of target movement trajectory, so it is suitable to solve the prediction and tracking problems of the small unmanned aerial vehicles because of the better adaptability of irregular movement. This paper has set up model set of constant velocity model (CV), constant acceleration model (CA), constant turning model (CT) and current statistical model. And the results of simulating and analyzing the real movement trajectory data of the small unmanned aerial vehicles show that the prediction and tracking technology based on the interacting multiple model algorithm can get relatively lower tracking error and improve tracking precision

  7. Technical Education Outreach in Materials Science and Technology Based on NASA's Materials Research

    Science.gov (United States)

    Jacobs, James A.

    2003-01-01

    The grant NAG-1 -2125, Technical Education Outreach in Materials Science and Technology, based on NASA s Materials Research, involves collaborative effort among the National Aeronautics and Space Administration s Langley Research Center (NASA-LaRC), Norfolk State University (NSU), national research centers, private industry, technical societies, colleges and universities. The collaboration aims to strengthen math, science and technology education by providing outreach related to materials science and technology (MST). The goal of the project is to transfer new developments from LaRC s Center for Excellence for Structures and Materials and other NASA materials research into technical education across the nation to provide educational outreach and strengthen technical education. To achieve this goal we are employing two main strategies: 1) development of the gateway website and 2) using the National Educators Workshop: Update in Engineering Materials, Science and Technology (NEW:Updates). We have also participated in a number of national projects, presented talks at technical meetings and published articles aimed at improving k-12 technical education. Through the three years of this project the NSU team developed the successful MST-Online site and continued to upgrade and update it as our limited resources permitted. Three annual NEW:Updates conducted from 2000 though 2002 overcame the challenges presented first by the September 11,2001 terrorist attacks and the slow U.S. economy and still managed to conduct very effective workshops and expand our outreach efforts. Plans began on NEW:Update 2003 to be hosted by NASA Langley as a part of the celebration of the Centennial of Controlled Flight.

  8. Structural capital, innovation capability, and company performance in technology-based colombian firms

    Directory of Open Access Journals (Sweden)

    Nekane Aramburu

    2015-03-01

    Full Text Available In today’s economy, innovation is considered to be one of the main driving forces behind business competitiveness, if not the most relevant one. Traditionally, the study of innovation has been addressed from different perspectives. Recently, literature on knowledge management and intellectual capital has provided new insights. Considering this, the aim of this paper is to analyze the impact of different organizational conditions – i.e. “structural capital” – on innovation capability and innovation performance, from an “intellectual capital” (IC perspective. As regards innovation capability, two dimensions are considered: new idea generation and innovation project management. The population subject to study is made up of technology-based Colombian firms. In order to gather information about the relevant variables involved in the research, a questionnaire was designed and addressed to the CEOs of the companies making up the target population. The sample analyzed is made up of 69 companies and is large enough to carry out a statistical study based on structural equation modelling (partial least squares approach using PLS-Graph software (Chin and Frye, 2003. The results obtained show that structural capital explains to a great extent both the effectiveness of the new idea generation process and of innovation project management. However, the influence of each specific organizational component making up structural capital (organizational design, organizational culture, hiring and professional development policies, innovation strategy, technological capital, and external structure varies. Moreover, successful innovation project management is the only innovation capability dimension that exerts a significant impact on company performance.

  9. Why simulation can be efficient: on the preconditions of efficient learning in complex technology based practices

    Directory of Open Access Journals (Sweden)

    Hofmann Bjørn

    2009-07-01

    Full Text Available Abstract Background It is important to demonstrate learning outcomes of simulation in technology based practices, such as in advanced health care. Although many studies show skills improvement and self-reported change to practice, there are few studies demonstrating patient outcome and societal efficiency. The objective of the study is to investigate if and why simulation can be effective and efficient in a hi-tech health care setting. This is important in order to decide whether and how to design simulation scenarios and outcome studies. Methods Core theoretical insights in Science and Technology Studies (STS are applied to analyze the field of simulation in hi-tech health care education. In particular, a process-oriented framework where technology is characterized by its devices, methods and its organizational setting is applied. Results The analysis shows how advanced simulation can address core characteristics of technology beyond the knowledge of technology's functions. Simulation's ability to address skilful device handling as well as purposive aspects of technology provides a potential for effective and efficient learning. However, as technology is also constituted by organizational aspects, such as technology status, disease status, and resource constraints, the success of simulation depends on whether these aspects can be integrated in the simulation setting as well. This represents a challenge for future development of simulation and for demonstrating its effectiveness and efficiency. Conclusion Assessing the outcome of simulation in education in hi-tech health care settings is worthwhile if core characteristics of medical technology are addressed. This challenges the traditional technical versus non-technical divide in simulation, as organizational aspects appear to be part of technology's core characteristics.

  10. Long-term safety and efficacy of Omnitrope®, a somatropin biosimilar, in children requiring growth hormone treatment: Italian interim analysis of the PATRO Children study.

    Science.gov (United States)

    Iughetti, Lorenzo; Tornese, Gianluca; Street, Maria Elisabeth; Napoli, Flavia; Giavoli, Claudia; Antoniazzi, Franco; Stagi, Stefano; Luongo, Caterina; Azzolini, Sara; Ragusa, Letizia; Bona, Gianni; Zecchino, Clara; Aversa, Tommaso; Persani, Luca; Guazzarotti, Laura; Zecchi, Emiliano; Pietropoli, Alberto; Zucchini, Stefano

    2016-11-03

    PATRO Children is an ongoing observational, longitudinal, non-interventional, global post-marketing surveillance study, which is investigating the long-term safety and effectiveness of Omnitrope®, a somatropin biosimilar to Genotropin®, in children with growth disturbances. The primary endpoint of PATRO Children is long-term safety and the secondary endpoint is effectiveness, which is assessed by analysing auxological data such as height (HSDS) and height velocity (HVSDS) standard deviation scores. Here, we report the data from the Italian interim analysis of PATRO Children data up to August 2015. PATRO Children is enrolling children who are diagnosed with conditions of short stature requiring GH treatment and are receiving Omnitrope®. Adverse events (AEs) are assessed in all Omnitrope®-treated patients. Height is evaluated yearly to near-adult (final) height, and is herein reported as HSDS; height velocity is also assessed and reported as a standard deviation score (HVSDS). Up to August 2015, a total of 186 patients (mean age 10.2 years, 57.5 % males) were enrolled :156 [84 %] had growth hormone deficiency, 12 [6.5 %] were born small for gestational age, seven [3.8 %] had Prader-Willi syndrome, one [0.5 %] had Turner syndrome and one [0.5 %] had chronic renal insufficiency; seven [3.8 %] patients had other indication profiles. The mean treatment duration with Omnitrope® was 28.1 ± 19.1 months. AEs were reported in 35.6 % of patients and included headache, pyrexia, arthralgia, abdominal pain, leg and/or arm pain and increased blood creatine phosphokinase. Two serious AEs in two patients were thought to be drug-related; one patient experienced a minimal increase in a known residual craniopharyngioma, and another a gait disturbance with worsening of walking difficulties. Similar to investigational studies, Omnitrope® treatment was associated with improvements in both HSDS and HVSDS. Omnitrope® appears to be well tolerated and effective for the

  11. 有生育要求的多囊卵巢综合征患者的治疗%Treatment for polycystic ovary syndrome patients with fertility requirement

    Institute of Scientific and Technical Information of China (English)

    刘振腾; 郝翠芳

    2014-01-01

    POlycystic Ovary syndrOme( PCOS)is the mOst cOmmOn cause Of anOvulatOry infertility. There are many nOn - PharmacOlOgic and PharmacOlOgic OPtiOns tO induce OvulatiOn,and eventually PrOvide a successful live birth in PCOS Patients with fertility requirement. First - line OvulatiOn inductiOn theraPy includes lifestyle change and clOmiPhene. GOnadOtrOPhins,laParOscOPic Ovarian drilling Or insulin sensitizing agents are secOnd line in clOmiPhene resistant PCOS Patients. If resOurces abOve are unsuccessful Or if Other infertility factOrs cOexist,ART is recOmmended as a third - line treatment. This review mainly PrOvides an intrOductiOn Of sPecific characteristics and current treatment PrOgress Of different methOds fOr OvulatiOn inductiOn,which can cOntribute tO design a mOre PersOnalized aPPrOach tO PCOS Patients with fertility requirement.%多囊卵巢综合征(POlycystic Ovary syndrOme,PCOS)是无排卵性不孕常见的原因,有多种非药物性和药物性方法帮助有生育要求的 PCOS 患者排卵并怀孕。一线疗法包括改变生活方式和克罗米芬治疗。对于克罗米芬抵抗的 PCOS 患者可采用二线疗法:使用促性腺激素(GOnadOtrOPhin,Gn)、腹腔镜下卵巢打孔术(laParOscOPic Ovarian drilling,LOD)或者胰岛素增敏剂。如果治疗无效或合并其他不孕因素,可采用三线疗法---辅助生殖技术(assisted rePrOductive technOlOgy,ART)。本文重点介绍每种疗法的特点和治疗进展,以便为 PCOS 患者制定更加个性化的治疗方案提供参考。

  12. The effectiveness of information and communication technology-based psychological interventions for paediatric chronic pain: protocol for a systematic review, meta-analysis and intervention content analysis.

    Science.gov (United States)

    Traynor, Angeline; Morrissey, Eimear; Egan, Jonathan; McGuire, Brian E

    2016-10-18

    Resource and geographic barriers are the commonly cited constraints preventing the uptake of psychological treatment for chronic pain management. For adults, there is some evidence to support the use of information and communication technology (ICT) as a mode of treatment delivery. However, mixed findings have been reported for the effectiveness and acceptability of psychological interventions delivered using information and communication technology for children and adolescents. This is a protocol for a review that aims to (i) evaluate the effectiveness of psychological interventions delivered using information and communication technology for children and adolescents with chronic pain and (ii) identify the intervention components and usability factors in technology-based treatments associated with behaviour change. We will conduct a systematic review to evaluate the effectiveness of psychological interventions for paediatric chronic pain delivered using ICT. We plan to directly compare ICT-based, psychological interventions with active control, treatment as usual or waiting list control conditions. This systematic review will be reported in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidance. Published and unpublished randomised controlled trials will be included and the literature search will comprise Ovid MEDLINE, Ovid Embase, PsycINFO and the Cochrane Library on Wiley, including CENTRAL and Cochrane Database of Systematic Reviews. Grey literature including theses, dissertations, technical and research reports will also be examined. Two review authors will independently conduct study selection, relevant data extraction and assessment of methodological quality. Risk of bias in included studies will be assessed using the Cochrane Collaboration risk of bias tool criteria. Two qualified coders will independently code behaviour change techniques according to the behaviour change taxonomy (v1) of 93 hierarchically

  13. Does white coat hypertension require treatment over age 80?: Results of the hypertension in the very elderly trial ambulatory blood pressure side project.

    Science.gov (United States)

    Bulpitt, Christopher J; Beckett, Nigel; Peters, Ruth; Staessen, Jan A; Wang, Ji-Guang; Comsa, Marius; Fagard, Robert H; Dumitrascu, Dan; Gergova, Vesselka; Antikainen, Riitta L; Cheek, Elizabeth; Rajkumar, Chakravarthi

    2013-01-01

    White coat hypertension is considered to be a benign condition that does not require antihypertensive treatment. Ambulatory blood pressure (ABP) was measured in 284 participants in the Hypertension in the Very Elderly Trial (HYVET), a double-blind randomized trial of indapamide sustained release 1.5 mg±perindopril 2 to 4 mg versus matching placebo in hypertensive subjects (systolic blood pressure 160-199 mm Hg) aged >80 years. ABP recordings (Diasys Integra II) were obtained in 112 participants at baseline and 186 after an average follow-up of 13 months. At baseline, clinic blood pressure (CBP) exceeded the morning ABP by 32/10 mm Hg. Fifty percent of participants fulfilled the established criteria for white coat hypertension. The highest ABP readings were in the morning (average 140/80 mm Hg), the average night-time pressure was low at 124/72 mm Hg, and the average 24-hour blood pressure was 133/77 mm Hg. During follow-up, the systolic/diastolic blood pressure placebo-active differences averaged 6/5 mm Hg for morning ABP, 8/5 mm Hg for 24-hour ABP, and 13/5 mm Hg for CBP. The lowering of blood pressure over 24 hours supports the reduction in blood pressure with indapamide sustained release±perindopril as the explanation for the reduction in total mortality and cardiovascular events observed in the main HYVET study. Because we estimate that 50% had white coat hypertension in the main study, this condition may benefit from treatment in the very elderly.

  14. DEVELOPING A TECHNOLOGY-BASED BUSINESS STRATEGY FOR THE INTERNATIONAL BUSINESS OF TELKOM SA

    Directory of Open Access Journals (Sweden)

    M. John

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: This study was aimed at developing a technology-based business strategy for Telkom’s international business. Deregulation, competition and demand for converging voice, data and video in the telecommunication market were the driving forces behind this study. Without a proper strategy, Telkom will not be able to withstand the new competition. As the initial step in strategy formulation, Telkom’s strategic goals were identified. A SWOT analysis was conducted and a strategy formulation map was developed. A technology balance sheet and S-curve models were developed to analyse the current products and technologies. It become evident through the research that there is a high potential for business expansion into Africa and Telkom has sufficient capabilities to support this. The implementation of voice over Internet protocol technology will enable Telkom to deliver international services at competitive rates. The study concluded by developing a technology strategy for Telkom’s international business. Recommendations are put forward and future research gaps are identified.

    AFRIKAANSE OPSOMMING: Die doel van hierdie studie was om ‘n tegnologie-gebaseerde besigheidstrategie vir Telkom se internasionale besigheid te ontwikkel. Deregulering, mededinging en die vraag na konvergensie van stem, data en video in die telekommunikasiemark was die dryfkragte agter hierdie studie. Sonder ‘n behoorlike strategie sal Telkom nie teen die nuwe mededinging kan staande bly nie. As eerste stap in die formulering van ‘n strategie, is Telkom se doelwitte geïdentifiseer. ‘n SWOT-analise is uitgevoer en ‘n strategieformuleringskaart is ontwikkel. ‘n Tegnologiebalansstaat en S-krommemodelle is ontwikkel om die bestaande produkte en tegnologieë te ontleed. Hierdie navorsing het aangetoon dat daar ‘n hoë potensiaal vir uitbreiding van Telkom se besigheid in Afrika bestaan en dat Telkom genoegsame vermoëns besit om dit te

  15. Federal register, Volume 60, No. 234, Wednesday, December 6, 1995 proposed rules. Part 2. 40 CFR part 122, et al. National pollutant discharge elimination system permit application requirements for publicly owned treatment works and other treatment works treating domestic sewage; proposed rule

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-06

    The Environmental Protection Agency proposes to amend permit application requirements and application forms for publicly owned treatment works (POTWs) and other treatment works treating domestic sewage (TWTDS). TWTDS include facilities that generate sewage sludge, provide commercial treatment of sewage sludge, manufacture a product derived from sewage sludge, or provide disposal of sewage sludge.

  16. Technology-Based Communication and the Development of Interpersonal Competencies Within Adolescent Romantic Relationships: A Preliminary Investigation.

    Science.gov (United States)

    Nesi, Jacqueline; Widman, Laura; Choukas-Bradley, Sophia; Prinstein, Mitchell J

    2017-06-01

    This study investigated longitudinal associations between adolescents' technology-based communication and the development of interpersonal competencies within romantic relationships. A school-based sample of 487 adolescents (58% girls; Mage  = 14.1) participated at two time points, one year apart. Participants reported (1) proportions of daily communication with romantic partners via traditional modes (in person, on the phone) versus technological modes (text messaging, social networking sites) and (2) competence in the romantic relationship skill domains of negative assertion and conflict management. Results of cross-lagged panel models indicated that adolescents who engaged in greater proportions of technology-based communication with romantic partners reported lower levels of interpersonal competencies one year later, but not vice versa; associations were particularly strong for boys. © 2016 The Authors. Journal of Research on Adolescence © 2016 Society for Research on Adolescence.

  17. Report of the Defense Science Board Task Force on Defense Science and Technology Base for the 21st Century

    Science.gov (United States)

    2016-06-07

    equations are likely to be non- linear , the standard-matrix algebra -solution approach will probably not be applicable. Instead, an iterative optimization...and ultimately combat outcome. The depiction makes the problem seem fairly simple and linear . There is a flow from the technology base through...observation is that industry does not manage its research and development process in a linear fashion as does the Department of Defense. By linear , it is

  18. Influence of firm related factors and industrial policy regime on technology based capacity utilization in sugar industry in Nigeria

    Directory of Open Access Journals (Sweden)

    S. B. Akpan

    2011-09-01

    Full Text Available The study analyzed the technology based capacity utilization rate in sugar industry in Nigeria in the period 1970 to 2010. Data used in the study were obtained from the sugar firms, publications of the Central Bank of Nigeria and National Bureau of Statistics. Augmented Dicker Fuller unit root test was conducted on the specified data to ascertain their stationarity and order of integration. The result reveals that some variables were stationary at level while some were stationary at first difference. The diagnostic statistics from the multiple log linear regression on the specified variables confirmed the reliability of the model. The empirical result reveals that sugar cane price and sugar industry’s real energy consumption have significant negative relationship with the technology based capacity utilization in the sugar industry in Nigeria. On the other hand, the wage rate of skill workers, industry’s, real research expenditure, human capital and period of import substitution have significant positive influenced on the technology based capacity utilization rate in the industry. Our findings suggest that policy measures aim at expanding the hectares of industrial sugarcane and increase production of refined petroleum fuel in the country will promote capacity utilization in the industry. Also policies targeted on the intensification of research and improved worker’s remuneration in the sub-sector is strongly advocated.

  19. I Get to Use an iPod in School? Using Technology-Based Advance Organizers to Support the Academic Success of English Learners

    Science.gov (United States)

    Billings, Elsa S.; Mathison, Carla

    2012-08-01

    This study investigated the impact of technology-based advance organizers (TBAOs) on the academic performance of 240 4th grade English learners (ELs) participating in a science class in School in the Park (SITP), a museum-school collaboration. While SITP provides a rich, hands-on learning environment, ELs face significant linguistic challenges in their ability to access the dense academic language and concepts provided in SITP's English only curriculum, thus negatively impacting ELs' engagement and learning. The TBAOs were designed in response to this issue. The study investigated two forms of treatment: TBAOs viewed on individual handheld mobile devices (HMDs), specifically iPods; and, TBAOs viewed as a whole class on DVD. The study utilized both qualitative and quantitative data sources, including a pre- and posttest, hands-on and performance-based assessments, as well as focus interviews. Results showed a significant interaction effect between group assignment, language status and application assessments, indicating ELs performed significantly better in the treatment groups. Students who used the HMD instead of the DVD or no treatment improved their total scores significantly on hands-on, performance-based measurements. Differences between treatment and control groups' performance on pre-/posttests approached significance. Furthermore, students reported TBAOs supported learning by introducing new material, introducing and reviewing daily academic vocabulary, and helping them anticipate behavioral and procedural expectations of hands-on activities. Classroom and museum educators reported an increase in the treatment groups' motivation and engagement. The study provided important implications in the use and power of learner-controlled technology in supporting ELs' linguistic and academic success.

  20. Treatment of municipal wastewater in full-scale on-site sand filter reduces BOD efficiently but does not reach requirements for nitrogen and phosphorus removal.

    Science.gov (United States)

    Laaksonen, Petteri; Sinkkonen, Aki; Zaitsev, Gennadi; Mäkinen, Esa; Grönroos, Timo; Romantschuk, Martin

    2017-04-01

    A traditional sand filter for treatment of household wastewater was constructed in the fall of 2012 at Biolinja 12, Turku, Finland. Construction work was led and monitored by an authorized wastewater treatment consultant. The filter was placed on a field bordered by open ditches from all sides in order to collect excess rain and snowmelt waters. The filter was constructed and insulated from the environment so that all outflowing water was accounted for. Untreated, mainly municipal, wastewater from Varissuo suburb was pumped from a sewer separately via three septic tanks (volume = 1 m(3) each) into the filters. Normally, wastewater was distributed to ground filters automatically according to pre-programmed schedule. Initially, the daily flow was 1200 L day(-1) to reflect the average organic load of a household of five persons (load: ca 237 g day(-1) BOD; 73 g day(-1) total N; and 10.4 g day(-1) total P). Later in the test, the flow rate was decreased first to 900 and then to 600 L day(-1) to better reflect the average volume produced by five persons. Volumes of inlet wastewater as well as treated water were monitored by magnetic flow meters. Samples were withdrawn from the inlet water, from the water entering the filters after the third septic tank, and from the outflowing water. After an initial adaption time, the reductions in BOD and chemical oxygen demand were constantly between 92 and 98%, showing that the biological degradation process in the filters functioned optimally and clearly comply with the national and EU standards. The reduction in total nitrogen and total phosphorus, however, reached required levels only during the first months of testing, apparently when buildup of microbial biomass was still ongoing. After this initial period of 3 months showing satisfactory reduction levels, the reduction of total nitrogen varied between 5 and 25% and total phosphorus mostly between 50 and 65%. Nitrification was efficient in the filter, but as

  1. High Proportion of HIV-HCV Coinfected Patients with Advanced Liver Fibrosis Requiring Hepatitis C Treatment in Haiphong, Northern Vietnam (ANRS 12262)

    Science.gov (United States)

    Lacombe, Karine; Duong Thi, Huong; Pham Thi Hanh, Phuc; Truong Thi Xuan, Lien; Chu Thi, Nga; Luong Que, Anh; Vu Hai, Vinh; Nagot, Nicolas; Tuaillon, Edouard; Dominguez, Stéphanie; Lemoine, Maud

    2016-01-01

    Rationale and Aims Screening and treatment for chronic hepatitis C are very limited in Vietnam and clinical data on HCV-related liver disease in HIV-coinfected people are almost inexistent. This study aimed to assess the severity of liver fibrosis and its risk factors in HIV-HCV coinfected patients in Haiphong, Northern Vietnam. Methods A cross-sectional study was conducted at a HIV outpatient clinic. Consecutive HIV treated adults with positive HCV serology completed a standardised epidemiological questionnaire and had a comprehensive liver assessment including hepatic elastography (Fibroscan®, Echosens). Results From February to March 2014, 104 HIV-HCV coinfected patients receiving antiretroviral therapy (ART) were prospectively enrolled (99 males, median age: 35.8 (32.7–39.6) years, median CD4 count: 504 (361–624) /mm3. Of them, 93 (89.4%) had detectable HCV RNA (median 6.19 (4.95–6.83 Log10 IU/mL). Patients were mainly infected with genotypes 1a/1b (69%) and genotypes 6a/6e (26%). Forty-three patients (41.3%) had fibrosis ≥F2 including 24 patients (23.1%) with extensive fibrosis (F3) and/or cirrhosis (F4). In univariate analysis, excessive alcohol consumption, estimated time duration from HCV infection, nevirapine and lopinavir-based ARV regimen and CD4 nadir were associated factors of extensive fibrosis/cirrhosis. Alcohol abuse was the only independent factor of extensive fibrosis in multivariate analysis. Using Fibroscan® as a gold standard, the high thresholds of AST-to-platelet ratio index (APRI) and fibrosis-4 score (FIB-4) had very good performances for the diagnosis of extensive fibrosis/cirrhosis (Se: 90 and 100%, Sp:84 and 81%, AUROCs = 0.93, 95%CI: 0.86–0.99 and 0.96 (0.92–0.99), respectively). Conclusion In this study, nearly 25% of HIV-HCV coinfected patients successfully treated with ART have extensive fibrosis or cirrhosis, and therefore require urgently HCV treatment. PMID:27148964

  2. Telomere length is a biomarker of cumulative oxidative stress, biologic age, and an independent predictor of survival and therapeutic treatment requirement associated with smoking behavior.

    Science.gov (United States)

    Babizhayev, Mark A; Savel'yeva, Ekaterina L; Moskvina, Svetlana N; Yegorov, Yegor E

    2011-11-01

    population groups described in this study including elderly support the hypothesis that telomere length is a predictor of survival and therapeutic treatment requirement associated with smoking behavior.

  3. A neglected requirement for optimizing treatment of age-related osteoporosis: Replenishing the skeleton's base reservoir with net base-producing diets.

    Science.gov (United States)

    Sebastian, Anthony; Frassetto, Lynda A

    2016-06-01

    Osteoporosis is a disorder of bone in which the mass of the bone is reduced and the bone's architecture at the microscopic level is disordered. Together those abnormalities predispose affected individuals to experience fractures despite only minimal trauma (i.e., fragility fractures). Age related osteoporosis is a common type of osteoporosis that occurs with aging in both men and women usually beginning after the age of peak bone mass. Research has found that the disorder can be partially reversed by reducing the net amount of acid that is produced when consuming typical Western diets. However, the amelioration that results has not been so dramatic or so consistent that physicians have adopted the procedure as part of the standard treatment for age-related osteoporosis. We propose that reducing the net acid load from the diet is not sufficient to reverse age related osteoporosis because it fails to supply base needed to restore the large amount of base in bone that had been lost by reacting with the net acid load of the diet that had been consumed for years or decades. Reducing the net acid load from the diet might be expected to have little ameliorative effect or merely slow the progression of the disorder. We hypothesize that both to restore osteoporotic bone to, or nearly to, its pre-disease state, as well as to eliminate the risk of fragility fractures, requires consuming diets that produce net amounts of base to restore the base lost from years to decades of consuming diets that produce net amounts of acid. We hypothesize also that the excess base and attendant subclinical metabolic alkalosis will both stimulate the cellular process of bone formation and suppress the cellular process of bone resorption, and thereby implement the restorative process.

  4. A new oxalate co-conversion technology based on liquid/liquid extraction columns

    Energy Technology Data Exchange (ETDEWEB)

    Borda, Gilles; Ode, Denis; Duhamet, Jean; Allegri, Patrick [CEA Nuclear Energy Division - Fuel Cycle Technology Division - System and Chemical Engineering Device Marcoule - 30207 Bagnols sur Ceze (France)

    2008-07-01

    The current objective of fabricating non proliferating nuclear fuel by 'direct' coprecipitation of uranium, plutonium and minor actinides requires a new process to replace the (co)precipitation step. The technological impact of an increased capacity on the work zone could require the development of a different concept for a continuous device capable of ensuring the proposed goal. A new type of device designed and patented by the Cea was tested in 2007. The patent is for organic confinement in a pulsed column. First, precipitation of cerium or neodymium alone has been carried out in this device, with satisfactory results. Moreover, a recent test campaign demonstrated that a uranium-cerium co-precipitate easily forms when the two nitrates are mixed in a pulsed column of the same size operating under very similar process conditions. Qualitatively, the co-precipitate meets the process requirements. (authors)

  5. Continuous Positive Airway Pressure Therapy for Obstructive Sleep Apnea: Maximizing Adherence Including Using Novel Information Technology-based Systems.

    Science.gov (United States)

    Hevener, Bretton; Hevener, William

    2016-09-01

    Sleep apnea is a form of sleep-disordered breathing that is associated with an increase in disease comorbidities, mortality risks, health care costs, and traffic accidents. Sleep apnea is most commonly treated with positive airway pressure (PAP). PAP can be difficult for patients to tolerate. This leads to initial and long-term noncompliance. Most insurance companies require compliance with PAP treatment to cover ongoing reimbursements for the device and related disposable supplies. Therefore, there are both clinical and financial incentives to a sleep apneic patient's compliance with PAP therapy.

  6. Constraints experienced by female students pursuing science and technology-based university programmes in their learning of science in Ghana

    Directory of Open Access Journals (Sweden)

    Kwaku Darko Amponsah

    2014-05-01

    Full Text Available This paper is part of a larger study to investigate female students in science and technology-based university (STU programs in their motivation, perception and constraint in learning science at senior high school and consequently science and technology-based programs at the university level. The conceptual framework is rooted in Steele’s concept of stereotype threat, which is the experience of anxiety or concern in a situation where a person has the potential to confirm a negative stereotype about their social group. The investigation was conducted among 328 final year female students pursuing engineering, medicine, pharmacy and computer science/ICT at Kwame Nkrumah University of Science and Technology (KNUST, Kumasi, Ghana. The study utilized cross-sectional descriptive survey design. 328 final year female students in the 2008/2009 academic year pursuing engineering, medicine, pharmacy and computer science/ICT formed the sample. A Self-Report Survey Questionnaire on constraints female students experience in their learning of science was designed and administered. This study indicated that female students have to grapple with some challenges such as lack of funding, and the unavailability or expensive nature of some textbooks. One-way between group analysis of variance (ANOVA and Hotchberg GT2 Post hoc analyses indicated that there were significant differences in constraints among some of the four groups of students. It was concluded that Government and other stakeholders should provide funding, scholarships or bursaries to female students in order to enhance their full participation. These challenges may account in part to the low participation of females in science and technology-based programs.

  7. Service quality and perceived value of technology-based service encounters: evaluation of clinical staff satisfaction in Taiwan.

    Science.gov (United States)

    Hung, Chung-Jye; Chang, Hsin Hsin; Eng, Cheng Joo; Wong, Kit Hong

    2013-01-01

    Previous research has evaluated technology-based service encounters (TBSEs) in the delivery of health care by assessing patient satisfaction. This study examined service quality and perceived value of TBSEs used in health organisations from the perspective of clinical staff, with staff technology readiness as a moderator. A quantitative survey was conducted in Taiwan, across private and public healthcare organisations. Results showed that TBSEs had a direct effect on service quality and perceived value, which in turn had a direct effect on staff satisfaction in using TBSEs. However, service quality had no effect on perceived value when moderated by technology readiness. Theoretical and managerial implications of these findings are discussed.

  8. Application of confocal technology based on polycapillary X-ray optics in three-dimensional diffraction scanning analysis

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Tianxi, E-mail: stxbeijing@163.com [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Liu, Hehe; Liu, Zhiguo; Peng, Song [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Ma, Yongzhong [Center for Disease Control and Prevention of Beijing, Beijing 100013 (China); Sun, Weiyuan; Luo, Ping; Ding, Xunliang [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China)

    2014-03-15

    The confocal technology based on a polycapillary focusing X-ray lens in the excitation channel and a polycapillary parallel X-ray lens in the detection channel was used to perform three-dimensional energy dispersive X-ray diffraction scanning analysis of a copper film on a silicon substrate. A theoretical model of correcting the intensity of the diffracted X-rays from different parts of the sample in the confocal volume was designed. The point-to-point 3D diffraction information of the sample was obtained.

  9. The potential of technology-based psychological interventions for anorexia and bulimia nervosa: a systematic review and recommendations for future research.

    Science.gov (United States)

    Schlegl, Sandra; Bürger, Carolina; Schmidt, Luise; Herbst, Nirmal; Voderholzer, Ulrich

    2015-03-31

    Previous studies have shown an unmet need in the treatment of eating disorders. In the last decade, interest in technology-based interventions (TBIs) (including computer- and Internet-based interventions [CBIs] or mobile interventions) for providing evidence-based therapies to individuals with different mental disorders has increased. The aim of this review was to systematically evaluate the potential of TBIs in the field of eating disorders, namely for anorexia nervosa (AN) and bulimia nervosa (BN), for both prevention and treatment, and also for carers of eating disorder patients. A systematic literature search was conducted using Medline and PsycINFO. Bibliographies of retrieved articles were also reviewed without date or study type restrictions. Forty studies resulting in 45 publications reporting outcomes fulfilled the inclusion criteria: 22 randomized controlled trials, 2 controlled studies, and 16 uncontrolled studies. In total, 3646 patients were included. Overall, the studies provided evidence for the efficacy of guided CBIs, especially for BN patients and for compliant patients. Furthermore, videoconferencing also appeared to be a promising approach. Evaluation results of Internet-based prevention of eating disorders and Internet-based programs for carers of eating disorder patients were also encouraging. Finally, there was preliminary evidence for the efficacy of mobile interventions. TBIs may be an additional way of delivering evidence-based treatments to eating disorder patients and their use is likely to increase in the near future. TBIs may also be considered for the prevention of eating disorders and to support carers of eating disorder patients. Areas of future research and important issues such as guidance, therapeutic alliance, and dissemination are discussed.

  10. The Potential of Technology-Based Psychological Interventions for Anorexia and Bulimia Nervosa: A Systematic Review and Recommendations for Future Research

    Science.gov (United States)

    Bürger, Carolina; Schmidt, Luise; Herbst, Nirmal; Voderholzer, Ulrich

    2015-01-01

    Background Previous studies have shown an unmet need in the treatment of eating disorders. In the last decade, interest in technology-based interventions (TBIs) (including computer- and Internet-based interventions [CBIs] or mobile interventions) for providing evidence-based therapies to individuals with different mental disorders has increased. Objective The aim of this review was to systematically evaluate the potential of TBIs in the field of eating disorders, namely for anorexia nervosa (AN) and bulimia nervosa (BN), for both prevention and treatment, and also for carers of eating disorder patients. Methods A systematic literature search was conducted using Medline and PsycINFO. Bibliographies of retrieved articles were also reviewed without date or study type restrictions. Results Forty studies resulting in 45 publications reporting outcomes fulfilled the inclusion criteria: 22 randomized controlled trials, 2 controlled studies, and 16 uncontrolled studies. In total, 3646 patients were included. Overall, the studies provided evidence for the efficacy of guided CBIs, especially for BN patients and for compliant patients. Furthermore, videoconferencing also appeared to be a promising approach. Evaluation results of Internet-based prevention of eating disorders and Internet-based programs for carers of eating disorder patients were also encouraging. Finally, there was preliminary evidence for the efficacy of mobile interventions. Conclusions TBIs may be an additional way of delivering evidence-based treatments to eating disorder patients and their use is likely to increase in the near future. TBIs may also be considered for the prevention of eating disorders and to support carers of eating disorder patients. Areas of future research and important issues such as guidance, therapeutic alliance, and dissemination are discussed. PMID:25840591

  11. Research on free curved surface reconstructing technology based on laser tracker

    Science.gov (United States)

    He, Binggao; An, Zhiyong; Gao, Yuhan; Li, Lijuan

    2011-11-01

    This paper studied the 3-D reconstructing technology of free curved surface. Initially, it scanned the local model of flight vehicle to use the new digital measuring equipment-laser tracker, got the point clouds of the model. And then, it reconstructed curved surface of the model by using the powerful modeling function of CATIA. Finally, the paper also utilized the units of alignment and data processing to make a relative error analysis of the reconstructed model and point clouds. The experiment conclusion showed that the method of measurement accorded with error requirements, and had the practical value of industrial application and production.

  12. Comprehensive, technology-based, team approach for a patient with locked-in syndrome: A case report of improved function & quality of life.

    Science.gov (United States)

    McNair, Keara; Lutjen, Madeline; Langhamer, Kara; Nieves, Jeremiah; Hreha, Kimberly

    2017-07-27

    One of the most severe types of stroke is locked-in syndrome (LIS) due to the loss of almost all voluntary motor functions and a high mortality rate. The majority of the literature regarding LIS is based on case reports that utilized multidisciplinary interventions focused on improving functional communication and respiratory care with minimal focus on motor retraining. These reports were neither dynamic nor multi-sensory, and the only technology utilized was in the form of augmentative communication. There are additional types of technology frequently used in the general stroke population that can address similar motor deficits that occur in the LIS population. This case report explains an interdisciplinary approach using motor and communication interventions that are multisensory, progressive, multi-modal, and technology- based. The length of stay was 153 days in acute rehabilitation, after which the patient returned home making significant gains in overall function. In this patient, the FIM changes in motor (+42), cognitive (+29) and total change score of (+71) surpassed what was determined to be a minimal clinically important difference. These results suggest that this treatment program and approach may be a key reason why this patient was able to achieve significant functional gains and report improved quality of life.

  13. Dignity and Deferral Narratives as Strategies in Facilitated Technology-Based Support Groups for People with Advanced Cancer

    Directory of Open Access Journals (Sweden)

    Annette F. Street

    2012-01-01

    Full Text Available This paper examines the value of facilitated telephone and online support groups for palliative care. Telephone interviews were conducted with twenty people living with advanced cancer who had participated in either a telephone or online support group facilitated by the Cancer Council Victoria, Melbourne, Australia. Two dominant participant narratives emerged: a focus on dying with dignity or an interest in deferring discussion of death and dying to focus on the present. Despite the different approaches, participants found the technology-based support groups to be accessible and safe environments in which to discuss difficult topics in privacy. Technology-based strategies provide opportunities for health professionals to provide social and emotional care to more people by moving beyond individualised care and facilitate peer-to-peer support at the end of life, especially to those with specific needs. Such options are feasible for palliative care services to set up and acceptable to a group of clients, especially for younger clients or those socially or geographically isolated.

  14. Performances for confocal X-ray diffraction technology based on polycapillary slightly focusing X-ray optics

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Hehe; Liu, Zhiguo [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Sun, Tianxi, E-mail: stxbeijing@163.com [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Peng, Song [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Ma, Yongzhong [Center for Disease Control and Prevention of Beijing, Beijing 100013 (China); Sun, Weiyuan; Li, Yude; Lin, Xiaoyan; Zhao, Weigang; Zhao, Guangcui; Luo, Ping; Pan, Qiuli; Ding, Xunliang [The Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, Beijing Normal University, Beijing 100875 (China); College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China)

    2013-09-21

    The confocal X-ray diffraction (XRD) technology based on a polycapillary slightly focusing X-ray lens (PSFXRL) in excitation channel and a polycapillary parallel X-ray lens (PPXRL) with a long input focal distance in detection channel was developed. The output focal spot of the PSFXRL and the input focal spot of the PPXRL were adjusted in confocal configuration, and only the X-rays from the volume overlapped by these foci could be accordingly detected. This confocal configuration was helpful in decreasing background. The convergence of the beam focused by the PSFXRL and divergence of the beam which could be collected by the PPXRL with a long input focal distance were both about 9 mrad at 8 keV. This was helpful in improving the resolution of lattice spacing of this confocal XRD technology. The gain in power density of such PSFXRL and PPXRL was about 120 and 7 at 11 keV, respectively, which was helpful in using the low power source to perform XRD analysis efficiently. The performances of this confocal XRD technology were provided, and some common plastics were analyzed. The experimental results demonstrated that the confocal diffraction technology base on polycapillary slightly focusing X-ray optics had wide potential applications.

  15. Design and Implementation of Area Optimized, Low Complexity CMOS 32nm Technology Based NCO

    Directory of Open Access Journals (Sweden)

    Miss. Amruta Upase

    2017-05-01

    Full Text Available A numerically controlled oscillator (NCO is a digital signal generator which is a very important block in many Digital Communication Systems such as Software Defined Radios, Digital Radio set and Modems, Down/Up converters for Cellular and PCS base stations etc. NCO creates a synchronous, discrete-time, discrete-valued representation of a sinusoidal waveform. This paper implements the development and design of CMOS look up Table based numerically controlled oscillator which improves the performance, reduces the power & area requirement. The design is implemented with CMOS 32 nm Technology with Microwind 3.8 software tool. In addition, it can be used for analog circuit also enables the integration of complete system on chip. This paper also describes the design of a NCO which is of contemporary nature with reasonable speed, resolution and linearity with lower power, low area. For all about Pre Layout simulation has been realized using 32nm CMOS process Technology.

  16. A Review on Radio-Over-Fiber Technology-Based Integrated (Optical/Wireless) Networks

    Science.gov (United States)

    Rajpal, Shivika; Goyal, Rakesh

    2017-03-01

    In the present paper, radio-over-fiber (RoF) technology has been proposed, which is the integration of the optical and radio networks. With a high transmission capacity, comparatively low cost and low attenuation, optical fiber provides an ideal solution for accomplishing the interconnections. In addition, a radio system enables the significant mobility, flexibility and easy access. Therefore, the system integration can meet the increasing demands of subscribers for voice, data and multimedia services that require the access network to support high data rates at any time and any place inexpensively. RoF has the potentiality to the backbone of the wireless access network and it has gained significant momentum in the last decade as a potential last-mile access scheme. This paper gives the comprehensive review of RoF technology used in the communication system. Concept, applications, advantages and limitations of RoF technology are also discussed in this paper.

  17. Research of aerial imaging spectrometer data acquisition technology based on USB 3.0

    Science.gov (United States)

    Huang, Junze; Wang, Yueming; He, Daogang; Yu, Yanan

    2016-11-01

    With the emergence of UAV (unmanned aerial vehicle) platform for aerial imaging spectrometer, research of aerial imaging spectrometer DAS(data acquisition system) faces new challenges. Due to the limitation of platform and other factors, the aerial imaging spectrometer DAS requires small-light, low-cost and universal. Traditional aerial imaging spectrometer DAS system is expensive, bulky, non-universal and unsupported plug-and-play based on PCIe. So that has been unable to meet promotion and application of the aerial imaging spectrometer. In order to solve these problems, the new data acquisition scheme bases on USB3.0 interface.USB3.0 can provide guarantee of small-light, low-cost and universal relying on the forward-looking technology advantage. USB3.0 transmission theory is up to 5Gbps.And the GPIF programming interface achieves 3.2Gbps of the effective theoretical data bandwidth.USB3.0 can fully meet the needs of the aerial imaging spectrometer data transmission rate. The scheme uses the slave FIFO asynchronous data transmission mode between FPGA and USB3014 interface chip. Firstly system collects spectral data from TLK2711 of high-speed serial interface chip. Then FPGA receives data in DDR2 cache after ping-pong data processing. Finally USB3014 interface chip transmits data via automatic-dma approach and uploads to PC by USB3.0 cable. During the manufacture of aerial imaging spectrometer, the DAS can achieve image acquisition, transmission, storage and display. All functions can provide the necessary test detection for aerial imaging spectrometer. The test shows that system performs stable and no data lose. Average transmission speed and storage speed of writing SSD can stabilize at 1.28Gbps. Consequently ,this data acquisition system can meet application requirements for aerial imaging spectrometer.

  18. Feasibility of mHealth and Near Field Communication technology based medication adherence monitoring.

    Science.gov (United States)

    Morak, Juergen; Schwarz, Mark; Hayn, Dieter; Schreier, Guenter

    2012-01-01

    Poor patients' adherence to intake of prescribed medication has been identified as a serious problem in the treatment of chronically ill patients. Technical solutions are needed to measure and - if necessary - to increase the patients' adherence. A telemonitoring solution was developed to record a patient's medication intake based on smart blisters and mobile phones with NFC functionality. The components allowed recording of drug type, timestamp, and dosage of pills taken. The system's usability and technical feasibility was evaluated in the course of an application study. Over a period of 13 months 59 patients suffering from diabetes were monitored. 1,760 blisters were handed out to these patients and 14,843 takeout events were recorded and transmitted via mobile phone. Results indicate the feasibility of this concept to monitor adherence. Although the system still needs to be optimized for routine use it shows the potential for targeting the problem of poor patient adherence by NFC enabled devices.

  19. Report: EPA Has Not Met Statutory Requirements for Hazardous Waste Treatment, Storage and Disposal Facility Inspections, but Inspection Rates Are High

    Science.gov (United States)

    Report #16-P-0104, March 11, 2016. Although the EPA’s overall inspection completion rate is high, the agency did not fully meet the legal requirement for inspecting 100 percent of operating TSDFs for fiscal year 2014.

  20. Label-free glucose detection using cantilever sensor technology based on gravimetric detection principles.

    Science.gov (United States)

    Hsieh, Shuchen; Hsieh, Shu-Ling; Hsieh, Chiung-Wen; Lin, Po-Chiao; Wu, Chun-Hsin

    2013-01-01

    Efficient maintenance of glucose homeostasis is a major challenge in diabetes therapy, where accurate and reliable glucose level detection is required. Though several methods are currently used, these suffer from impaired response and often unpredictable drift, making them unsuitable for long-term therapeutic practice. In this study, we demonstrate a method that uses a functionalized atomic force microscope (AFM) cantilever as the sensor for reliable glucose detection with sufficient sensitivity and selectivity for clinical use. We first modified the AFM tip with aminopropylsilatrane (APS) and then adsorbed glucose-specific lectin concanavalin A (Con A) onto the surface. The Con A/APS-modified probes were then used to detect glucose by monitoring shifts in the cantilever resonance frequency. To confirm the molecule-specific interaction, AFM topographical images were acquired of identically treated silicon substrates which indicated a specific attachment for glucose-Con A and not for galactose-Con A. These results demonstrate that by monitoring the frequency shift of the AFM cantilever, this sensing system can detect the interaction between Con A and glucose, one of the biomolecule recognition processes, and may assist in the detection and mass quantification of glucose for clinical applications with very high sensitivity.

  1. Research of B2B e-Business Application and Development Technology Based on SOA

    Science.gov (United States)

    Xian, Li Liang

    Today, the B2B e-business systems in most enterprises usually have multiple heterogeneous and independent systems which are based on different platforms and operate in different functional departments. To deal with the increased services in future, an enterprise needs to expand its system continuously. This, however, will cause great inconvenience to the future system maintenance. To implement e-business successfully, a unified internal e-business integration environment must be established to integrate the internal system and thus realize a unified internal mechanism within the enterprise e-business system. The SOA (service-oriented architecture), however, can well meet the above requirements. The integration of SOA-based applications can reduce the dependency of different types of IT systems, reduce the cost of system maintenance and the complexity of the IT system operation, increase the flexibility of the system deployment, and at the same time exclude the barrier of service innovation. Research and application of SOA-based enterprise application systems has become a very important research project at present. Based on SOA, this document designs an enterprise e-business application model and realizes a flexible and expandable e-business platform.

  2. Label-Free Glucose Detection Using Cantilever Sensor Technology Based on Gravimetric Detection Principles

    Directory of Open Access Journals (Sweden)

    Shuchen Hsieh

    2013-01-01

    Full Text Available Efficient maintenance of glucose homeostasis is a major challenge in diabetes therapy, where accurate and reliable glucose level detection is required. Though several methods are currently used, these suffer from impaired response and often unpredictable drift, making them unsuitable for long-term therapeutic practice. In this study, we demonstrate a method that uses a functionalized atomic force microscope (AFM cantilever as the sensor for reliable glucose detection with sufficient sensitivity and selectivity for clinical use. We first modified the AFM tip with aminopropylsilatrane (APS and then adsorbed glucose-specific lectin concanavalin A (Con A onto the surface. The Con A/APS-modified probes were then used to detect glucose by monitoring shifts in the cantilever resonance frequency. To confirm the molecule-specific interaction, AFM topographical images were acquired of identically treated silicon substrates which indicated a specific attachment for glucose-Con A and not for galactose-Con A. These results demonstrate that by monitoring the frequency shift of the AFM cantilever, this sensing system can detect the interaction between Con A and glucose, one of the biomolecule recognition processes, and may assist in the detection and mass quantification of glucose for clinical applications with very high sensitivity.

  3. Software requirements

    CERN Document Server

    Wiegers, Karl E

    2003-01-01

    Without formal, verifiable software requirements-and an effective system for managing them-the programs that developers think they've agreed to build often will not be the same products their customers are expecting. In SOFTWARE REQUIREMENTS, Second Edition, requirements engineering authority Karl Wiegers amplifies the best practices presented in his original award-winning text?now a mainstay for anyone participating in the software development process. In this book, you'll discover effective techniques for managing the requirements engineering process all the way through the development cy

  4. Experimental Verification of Electric Drive Technologies Based on Artificial Intelligence Tools

    Science.gov (United States)

    Rubaai, Ahmed; Kankam, David (Technical Monitor)

    2003-01-01

    A laboratory implementation of a fuzzy logic-tracking controller using a low cost Motorola MC68HC11E9 microprocessor is described in this report. The objective is to design the most optimal yet practical controller that can be implemented and marketed, and which gives respectable performance, even when the system loads, inertia and parameters are varying. A distinguishing feature of this work is the by-product goal of developing a marketable, simple, functional and low cost controller. Additionally, real-time nonlinearities are not ignored, and a mathematical model is not required. A number of components have been designed, built and tested individually, and in various combinations of hardware and software segments. These components have been integrated with a brushless motor to constitute the drive system. A microprocessor-based FLC is incorporated to provide robust speed and position control. Design objectives that are difficult to express mathematically can be easily incorporated in a fuzzy logic-based controller by linguistic information (in the form of fuzzy IF-THEN rules). The theory and design are tested in the laboratory using a hardware setup. Several test cases have been conducted to confirm the effectiveness of the proposed controller. The results indicate excellent tracking performance for both speed and position trajectories. For the purpose of comparison, a bang-bang controller has been tested. The fuzzy logic controller performs significantly better than the traditional bang-bang controller. The bang-bang controller has been shown to be relatively inaccurate and lacking in robustness. Description of the implementation hardware system is also given.

  5. A new co conversion technology based on liquid/liquid extraction column

    Energy Technology Data Exchange (ETDEWEB)

    Borda, Gilles; Ode, Denis; Duhamet, Jean; Brackx, Emmanuelle [CEA Valrho - Marcoule - BP 17171 - 30207 Bagnols sur Ceze Cedex (France)

    2009-06-15

    The current objective of implementing 'direct' coprecipitation of uranium, plutonium and minor actinides for nuclear fuel re-fabrication leads to reconsider the (co)precipitation step, and more precisely its adaptability to new flowrates' specifications. Indeed, coprecipitation of a uranium fraction together with plutonium results in an appreciable increase in the process flow rates for this step. The technological impact of the increase in capacity could require the development of a different concept for a continuous device capable of ensuring the proposed process. A new type of device designed and patented by the CEA has been tested since 2007. The patent is for organic confinement in a pulsed column (PC) or Couette column (CC). The precipitation reaction between the oxalate complexing agent and a surrogate nitrate-cerium(II) or neodymium(III) alone, or coprecipitated uranium(IV) and cerium(III), occurs within an emulsion created in the device by these two phases flowing with a counter-current chemically inert organic phase (for example TPH) produced by the stirring action of the pulsator (PC) or the central rotor (CC). The precipitate is confined and thus does not form deposits on the vessel walls (which are also water-repellent); it flows downward by gravity and exits the column continuously into a settling tank. This paper describes the recent results obtained with this new technology for precipitation of Ce and Nd and coprecipitation of U + Ce in pulsed column and Couette column. It describes a first modeling allowing further extrapolation of this device to high capacities. (authors)

  6. Method for screening prevention and control measures and technologies based on groundwater pollution intensity assessment.

    Science.gov (United States)

    Li, Juan; Yang, Yang; Huan, Huan; Li, Mingxiao; Xi, Beidou; Lv, Ningqing; Wu, Yi; Xie, Yiwen; Li, Xiang; Yang, Jinjin

    2016-05-01

    This paper presents a system for determining the evaluation and gradation indices of groundwater pollution intensity (GPI). Considering the characteristics of the vadose zone and pollution sources, the system decides which anti-seepage measures should be implemented at the contaminated site. The pollution sources hazards (PSH) and groundwater intrinsic vulnerability (GIV) are graded by the revised Nemerow Pollution Index and an improved DRTAS model, respectively. GPI is evaluated and graded by a double-sided multi-factor coupling model, which is constructed by the matrix method. The contaminated sites are categorized as prior, ordinary, or common sites. From the GPI results, we develop guiding principles for preventing and removing pollution sources, procedural interruption and remediation, and end treatment and monitoring. Thus, we can select appropriate prevention and control technologies (PCT). To screen the technological schemes and optimize the traditional analytical hierarchy process (AHP), we adopt the technique for order preference by the similarity to ideal solution (TOPSIS) method. Our GPI approach and PCT screening are applied to three types of pollution sites: the refuse dump of a rare earth mine development project (a potential pollution source), a chromium slag dump, and a landfill (existing pollution sources). These three sites are identified as ordinary, prior, and ordinary sites, respectively. The anti-seepage materials at the refuse dump should perform as effectively as a 1.5-m-thick clay bed. The chromium slag dump should be preferentially treated by soil flushing and in situ chemical remediation. The landfill should be treated by natural attenuation technology. The proposed PCT screening approach was compared with conventional screening methods results at the three sites and proved feasible and effective. The proposed method can provide technical support for the monitoring and management of groundwater pollution in China. Copyright © 2015

  7. Exploring the Structural Requirements for Inhibition of the Ubiquitin E3 Ligase Breast Cancer Associated Protein 2 (BCA2)a as a Treatment for Breast Cancer

    OpenAIRE

    Brahemi, Ghali; Kona, Fathima R; Fiasella, Annalisa; Buac, Daniela; Soukupová, Jitka; Brancale, Andrea; Burger, Angelika M; Westwell, Andrew D.

    2010-01-01

    The zinc-ejecting aldehyde dehydrogenase (ALDH) inhibitory drug disulfiram (DSF) was found to be a breast cancer-associated protein 2 (BCA2) inhibitor with potent antitumor activity. We herein describe our work in the synthesis and evaluation of new series of zinc-affinic molecules to explore the structural requirements for selective BCA2-inhibitory antitumor activity. An N(C=S)S-S motif was found to be required, based on selective activity in BCA2-expressing breast cancer cell lines and agai...

  8. Energy requirements

    NARCIS (Netherlands)

    Hulzebos, Christian V.; Sauer, Pieter J. J.

    2007-01-01

    The determination of the appropriate energy and nutritional requirements of a newborn infant requires a clear goal of the energy and other compounds to be administered, valid methods to measure energy balance and body composition, and knowledge of the neonatal metabolic capacities. Providing an appr

  9. Energy requirements

    NARCIS (Netherlands)

    Hulzebos, Christian V.; Sauer, Pieter J. J.

    The determination of the appropriate energy and nutritional requirements of a newborn infant requires a clear goal of the energy and other compounds to be administered, valid methods to measure energy balance and body composition, and knowledge of the neonatal metabolic capacities. Providing an

  10. A framework for identifying the applicability of heating or cooling technologies based on initial project information

    Science.gov (United States)

    Cacace, Katie Meng

    In order to fully achieve the energy savings and human comfort benefits of many alternative heating and cooling technologies, design considerations for these technologies must be made during the conceptual design stage. However, at this stage architects are often faced with challenges that inhibit the integration of such technologies. At the early stages of design, architects have limited time and technical knowledge to research alternative technologies and mechanical engineers are typically not yet part of the design team to offer their expertise. To address these problems, this research developed a framework for a Technology Identifier that would inform an architect about alternative heating and cooling technologies that are applicable to their specific project at the conceptual design stage. The framework is based on the premise that a quantitative relationship between the initial project information and a technology's critical output variable(s) for heat transfer to the space can be established. Therefore, to be included in the framework a technology must possess a component that provides direct heat transfer to the space for the framework to determine if the technology can maintain the desired space temperature. The climatic influences on a technology's performance and the effect of changing a technology's input variables on the heat transfer output variable(s) were also quantified. Existing building energy simulation programs were used in these analyses. The framework develops simulation input files for multiple technologies, utilizes existing simulation programs to predict the performance of these technologies, and then displays the output results along with other information that is useful to designers at the conceptual stage. Each simulation input file is compiled from a template that queries databases and requires minimal user input. The output display includes the space temperature, energy consumption, and design considerations of each technology. A

  11. Technology-Based Innovations to Foster Personalized Healthy Lifestyles and Well-Being: A Targeted Review

    Science.gov (United States)

    Santana, Silvina; Tsiknakis, Manolis; Marias, Kostas; Sakkalis, Vangelis; Teixeira, António; Janssen, Joris H; de Jong, Henri; Tziraki, Chariklia

    2016-01-01

    organizational dynamics. Conclusions Delivering innovative ubiquitous eHealth and mHealth services, including citizen-centered wellness and lifestyle management services, goes well beyond the development of technical solutions. For the large-scale information and communication technology-supported adoption of healthier lifestyles to take place, crucial innovations are needed in the process of making and deploying usable empowering end-user services that are trusted and user-acceptable. Such innovations require multidomain, multilevel, transdisciplinary work, grounded in theory but driven by citizens’ and health care professionals’ needs, expectations, and capabilities and matched by business ability to bring innovation to the market. PMID:27342137

  12. Method for screening prevention and control measures and technologies based on groundwater pollution intensity assessment

    Energy Technology Data Exchange (ETDEWEB)

    Li, Juan, E-mail: lijuan@craes.org.cn [College of Water Sciences, Beijing Normal University, Beijing 100875 (China); Chinese Research Academy of Environmental Sciences, Beijing 100012 (China); State Environmental Protection Key Laboratory of Simulation and Control of Groundwater Pollution, Beijing, 100012 (China); Yang, Yang [College of Environment, Beijing Normal University, Beijing 100875 (China); Chinese Research Academy of Environmental Sciences, Beijing 100012 (China); State Environmental Protection Key Laboratory of Simulation and Control of Groundwater Pollution, Beijing, 100012 (China); Huan, Huan; Li, Mingxiao [Chinese Research Academy of Environmental Sciences, Beijing 100012 (China); State Environmental Protection Key Laboratory of Simulation and Control of Groundwater Pollution, Beijing, 100012 (China); Xi, Beidou, E-mail: xibd413@yeah.net [Chinese Research Academy of Environmental Sciences, Beijing 100012 (China); State Environmental Protection Key Laboratory of Simulation and Control of Groundwater Pollution, Beijing, 100012 (China); Lanzhou Jiaotong University, Lanzhou 730070 (China); Lv, Ningqing [Chinese Research Academy of Environmental Sciences, Beijing 100012 (China); State Environmental Protection Key Laboratory of Simulation and Control of Groundwater Pollution, Beijing, 100012 (China); Wu, Yi [Guizhou Academy of Environmental Science and Designing, Guizhou 550000 (China); Xie, Yiwen, E-mail: qin3201@126.com [School of Chemical and Environmental Engineering, Dongguan University of Technology, Dongguan, 523808 (China); Li, Xiang; Yang, Jinjin [Chinese Research Academy of Environmental Sciences, Beijing 100012 (China); State Environmental Protection Key Laboratory of Simulation and Control of Groundwater Pollution, Beijing, 100012 (China)

    2016-05-01

    This paper presents a system for determining the evaluation and gradation indices of groundwater pollution intensity (GPI). Considering the characteristics of the vadose zone and pollution sources, the system decides which anti-seepage measures should be implemented at the contaminated site. The pollution sources hazards (PSH) and groundwater intrinsic vulnerability (GIV) are graded by the revised Nemerow Pollution Index and an improved DRTAS model, respectively. GPI is evaluated and graded by a double-sided multi-factor coupling model, which is constructed by the matrix method. The contaminated sites are categorized as prior, ordinary, or common sites. From the GPI results, we develop guiding principles for preventing and removing pollution sources, procedural interruption and remediation, and end treatment and monitoring. Thus, we can select appropriate prevention and control technologies (PCT). To screen the technological schemes and optimize the traditional analytical hierarchy process (AHP), we adopt the technique for order preference by the similarity to ideal solution (TOPSIS) method. Our GPI approach and PCT screening are applied to three types of pollution sites: the refuse dump of a rare earth mine development project (a potential pollution source), a chromium slag dump, and a landfill (existing pollution sources). These three sites are identified as ordinary, prior, and ordinary sites, respectively. The anti-seepage materials at the refuse dump should perform as effectively as a 1.5-m-thick clay bed. The chromium slag dump should be preferentially treated by soil flushing and in situ chemical remediation. The landfill should be treated by natural attenuation technology. The proposed PCT screening approach was compared with conventional screening methods results at the three sites and proved feasible and effective. The proposed method can provide technical support for the monitoring and management of groundwater pollution in China. - Highlights: • An

  13. Sensemaking processes of organizational identity and technological capabilities: an empirical study in new technology-based firms

    Directory of Open Access Journals (Sweden)

    Julio César Acosta-Prado

    2013-09-01

    Full Text Available This article analyzes the sensemaking processes of organizational identity and technological capabilities that are facilitators of innovation at New-Technology-Based Firms (NTBFs. The research proposal points out that in this kind of organization, the knowledge transferred by these processes simultaneously addresses two core aspects: their organizational identity and technological capabilities. From a theoretical point of view, our study links two conceptual frameworks (organizational identity and technological capabilities, rarely mentioned together in the preceding research. From a practical point of view, the findings identify these processes and suggest that in this kind of organization both take place simultaneously, which could help stakeholders improve their management. Hence, members and managers of these organizations should take these processes into account as a framework to achieve competitiveness and therefore success.

  14. Analytical Study of Interdisciplinary Relations in Selected High Priority Areas of Science and Technology Based on Data of ISI Database

    Directory of Open Access Journals (Sweden)

    Mehri Sedighi

    2014-03-01

    Full Text Available The purpose of this research is to investigate the interdisciplinary relations in selected high priority areas of science and technology based on ISI data. This is an applied study using scientometric, citation analysis and network analysis methods. After identifying and extracting data from WOS, in order to determine the interdisciplinary relations and the evolution of these relationships, all citations of these records have been analysed. In order to judge the interdisciplinarity of data, the results of the two approaches have been considered: 1-To determine the subject areas of the journals 2- To determine the institutional affiliation of the authors.There is a positive correlation between co-authorship and interdisciplinary approach in all studied areas. There is no significant relation between the number of citations and interdisciplinary approach. Mapping of interdisciplinary relationships in nanotechnology showed this is a unique method to discover the structural patterns of a research area.

  15. Texture Mapping Technology Based on OpenGL%基于OpenGL的纹理贴图技术

    Institute of Scientific and Technical Information of China (English)

    杨键; 张敏

    2011-01-01

    Texture map is a technical basis for enhancing realistic 3D scene.This paper mainly introduces the texture mapping technology based on OpenGL,including the basic steps for realizing texture map base on OpenGL,and technical key points of each link of textu%纹理贴图是增强3D场景真实感的技术基础,主要介绍了基于OpenGL的纹理贴图技术,包含实现OpenGL纹理贴图的基本步骤,以及纹理贴图各环节的技术要点,对OpenGL Mip贴图的原理和实现方法也进行了简要的介绍。

  16. Mobile technology use and desired technology-based intervention characteristics among HIV+ Black men who have sex with men.

    Science.gov (United States)

    Senn, Theresa E; Braksmajer, Amy; Coury-Doniger, Patricia; Urban, Marguerite A; Carey, Michael P

    2017-04-01

    HIV positive Black men who have sex with men (MSM) are retained in HIV medical care at suboptimal rates. Interventions targeted to Black MSM are needed to help to improve their retention in care. The purposes of this study were to investigate the use of mobile technology among HIV+ Black MSM and to explore participants' thoughts about the use of mobile technology for HIV retention in care interventions. Twenty-two HIV+ Black MSM completed a technology use survey and participated in a qualitative interview regarding technology-based interventions. The majority of participants (95%) had access to a cell phone, and used their phones frequently (median 3 hours/day). Men preferred interventions that would allow for anonymous participation and that would provide individually tailored support. Mobile technology is a promising approach to intervention delivery for both younger and older HIV+ Black MSM. These interventions should incorporate features that are desirable to men (i.e., anonymous participation and individual tailoring).

  17. Recommendations for an update of 2003 European regulatory requirements for registration of drugs to be used in the treatment of RA.

    Science.gov (United States)

    Smolen, Josef S; Boers, Maarten; Abadie, Eric C; Breedveld, Ferdinand C; Emery, Paul; Bardin, Thomas; Goel, Niti; Ethgen, Dominique J; Avouac, Bernard P; Dere, Willard H; Durez, Patrick; Matucci-Cerinic, Marco; Flamion, Bruno; Laslop, Andrea; Lekkerkerker, Frits J; Miossec, Pierre; Mitlak, Bruce H; Ormarsdóttir, Sif; Paolozzi, Laurence; Rao, Ravi; Reiter, Susan; Tsouderos, Yannis; Reginster, Jean-Yves

    2011-02-01

    Since 2003, the European Medicines Agency (EMA) document, 'Points to consider on clinical investigation of medicinal products other than NSAIDs (nonsteroidal anti-inflammatory drugs) for the treatment of rheumatoid arthritis' has provided guidance for the clinical development of both biologic and non-biologic disease-modifying antirheumatic drugs (DMARDs). In the last few years, several new products have been developed or are in development for the treatment of RA, which offer significant efficacy with regard to disease control, including prevention of structural damage and disability. Concurrently, novel insights have been gained with respect to the assessment of disease activity, joint damage and disability. New treatment strategies have been established which relate to early therapy, tight control and rapid switching of medication. Accordingly, several new EULAR/ACR recommendations have been or are being developed. Several important additions and changes are needed in the 2003 guidance to incorporate the current scientific knowledge into clinical trial design for the development of future products. Under the auspices of the Group for the Respect of Ethics and Excellence in Science (GREES), a group of experts in the field of RA and clinical trial design met to provide a consensus recommendation for an update to the 2003 EMA guidance document.

  18. Requirements dilemma

    OpenAIRE

    2006-01-01

    This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University. Knowing ‘what’ to build is an integral part of an Information System Development, and it is generally understood that this, which is known as Requirements, is achievable through a process of understanding, communication and management. It is currently maintained by the Requirements theorists that successful system design clarifies the interrelations between information and its representations...

  19. Can a serum acetaminophen concentration obtained less than 4 hours post-ingestion determine which patients do not require treatment with acetylcysteine?()

    Science.gov (United States)

    Yarema, Mark C; Green, Jason P; Sivilotti, Marco L A; Johnson, David W; Nettel-Aguirre, Alberto; Victorino, Charlemaigne; Spyker, Daniel A; Rumack, Barry H

    2017-02-01

    The interpretation of acetaminophen concentrations obtained prior to 4 hours after an acute, single overdose remains unclear. Patient care decisions in the Emergency Department could be accelerated if such concentrations could reliably exclude the need for treatment. To determine the agreement between a serum acetaminophen concentration obtained less than 4 hours after an acute ingestion and the subsequent 4 + hour concentration, and the predictive accuracy of early concentrations for identifying patients with potentially toxic exposures. A secondary analysis of patients admitted for acetaminophen poisoning at one of the 34 hospitals in eight Canadian cities from 1980 to 2005. We examined serum acetaminophen concentrations obtained less than 4 hours post-ingestion, and again 4 or more hours post-ingestion. For the diagnostic accuracy analysis, we specified a cutpoint of 100 μg/mL (662 μmol/L) obtained between 2 and 4 hours and a subsequent 4 to 20 hour acetaminophen concentration above the nomogram treatment line of 150 μg/mL (993 μmol/L). Of 2454 patients identified, 879 (36%) had a subsequent acetaminophen concentration above the nomogram treatment line. The 2-4 hour concentration demonstrated a sensitivity of 0.96 [95% CI; 0.94, 0.97] and a negative likelihood ratio of 0.070 [0.048, 0.10]. Coingested opioids reduced this sensitivity to 0.91 [0.83, 0.95], and antimuscarinics to 0.86 [0.72, 0.94]. Only very low to undetectable acetaminophen concentrations prior to 4 hours reliably excluded a subsequent concentration over the treatment line. Applying an acetaminophen concentration cutpoint of 100 μg/mL (662 μmol/L) at 2-4 hours after an acute ingestion as a threshold for repeat testing and/or treatment would occasionally miss potentially toxic exposures. Absorption of acetaminophen is only slightly delayed by coingested opioids or antimuscarinics. Our analysis validates the practice of not retesting when the first post-ingestion acetaminophen

  20. Evaluation of up-converting phosphor technology-based lateral flow strips for rapid detection of Bacillus anthracis Spore, Brucella spp., and Yersinia pestis.

    Directory of Open Access Journals (Sweden)

    Pingping Zhang

    Full Text Available Bacillus anthracis, Brucella spp., and Yersinia pestis are zoonotic pathogens and biowarfare- or bioterrorism-associated agents that must be detected rapidly on-site from various samples (e.g., viscera and powders. An up-converting phosphor technology-based lateral flow (UPT-LF strip was developed as a point-of-care testing (POCT to satisfy the requirements of first-level emergency response. We developed UPT-LF POCT to quantitatively detect the three pathogens within 15 min. Sample and operation-error tolerances of the assay were comprehensively evaluated. The sensitivity of UPT-LF assay to bacterial detection reached 10(4 cfu · mL(-1 (100 cfu/test, with a linear quantitative range of 4 to 6 orders of magnitude. Results revealed that the UPT-LF assay exhibited a high specificity with the absence of false-positive results even at 10(9 cfu · mL(-1 of non-specific bacterial contamination. The assay could tolerate samples with a wide pH range (2 to 12, high ion strengths (≥ 4 mol · L(-1 of NaCl, high viscosities (≤ 25 mg · mL(-1 of PEG20000 or ≥ 20% of glycerol, and high concentrations of bio-macromolecule (≤ 200 mg · mL(-1 of bovine serum albumin or ≥ 80 mg · mL(-1 of casein. The influence of various types of powders and viscera (fresh and decomposed on the performance of UPT-LF assay was determined. The operational error of liquid measurement exhibited few effects on sensitivity and specificity. The developed UPT-LF POCT assay is applicable under field conditions with excellent tolerance to sample complexity and operational error.

  1. District energy: an important factor in the socially and environmentally responsible solution for the electric power industry; (requiring greater accelerated capital cost allowance treatment for income tax purposes)

    Energy Technology Data Exchange (ETDEWEB)

    Boucher, P. [HSBC James Capel Canada Inc. (Canada); Stevens, S. [Business Development Consumers Utilities (Canada)

    1996-09-01

    The considerable amount of risk associated with the investment in district energy systems was discussed. It was explained that district energy projects frequently require additional capital allowances, particularly in the initial years of a typical project, in order to attract private capital investments to the industry. Advantages of district energy systems were reviewed, among them reduction in CO{sub 2} and NO{sub x} emissions, enhancing energy conservation through the use of high efficiency boilers or thermal waste energy, increasing tax revenue at various levels of government, providing much-needed capital injection into communities, providing construction and operation jobs, and allowing electric utilities to offer cogeneration from older plants helping to avoid stranded investments. 1 tab.

  2. 基于无线通信网络的移动电话定位新技术%A New Cellular Telephone Location Technology Based on Wireless Communication Network

    Institute of Scientific and Technical Information of China (English)

    张贵明黄顺吉; 张元莉

    2001-01-01

    由于GPS定位受多种因素的制约,提出了一种基于无线通信网络的移动电话定位新技术。该技术基于TDOA方法,只要求对现有移动通信网络中基站和控制中心的软硬件作适当的修改,就能实现对移动电话的定位和监控。该技术具有广阔的应用前景。%This paper presents a new cellular telephone location technology based on wireless communication network, which uses TDOA, only requires appropriate modification for hardware and software of base-station and control center, the location and tracking of cellular telephone will be realized. The application of this technology is wide.

  3. Children stomatology outpatient treatment requirements analysis and countermeasures%儿童口腔科门诊治疗需求特征分析及对策

    Institute of Scientific and Technical Information of China (English)

    夏斌; 秦满; 韩烨; 张笋

    2013-01-01

    To assess dental treatment needs and oral health status among children under 18-year-old in Beijing and to examine how these are affected by age, gender. Methods: In the retrospective study, 3 148 children aged 0. 8 -18. 0 years were selected from patients who first visit the Department of Paediatric Dentistry, Peking University School and Hospital of Stomatology, from May 2010 to January 2011. The treatment needs were evaluated and analysed. Results: Mean age of the group was 6. 23 ± 3.46, median was 5.0, and 52.4% (1 649/3 148) were boys. The percentages of treatment need for caries, pulptis and periapical periodontitis, teeth developmental abnormality, dental injury space management, periodontal disease, non carious disease and others were 35. 1% (1 105/3 148), 32. 2% (1013/3 148), 11.5% (363/3 148) and 6. 7% (212/3 148), 2.0% (62/3 148), 1. 3% (41/ 3 148), 0.1% (2/3 148) and 2. 2% (69/3 148) respectively. 3.6% (112/3 148) children suffered toothache and need an emergency dental treatment. In 1 602 children under 6-year-old, 55. 2% (884/ 1 602) were diagnosed as severe early childhood caries. Only 8.9% (281/3 148) children were found to need no treatment, who just asked a regular dental examine. Conclusion: Systematic implementation of preventive oral care and community-oriented health programmers for children, especially preschool-aged children, are urgently needed in China.%目的:回顾性分析到北京大学口腔医院儿童口腔科就诊的初诊患者的主诉和治疗需求,发现其特点并提出相应对策.方法:选择在2010年5月到2011年1月到北京大学口腔医院儿童口腔科就诊的3 148名患者作为研究对象,记录患者的年龄、性别、主诉、主要疾病诊断等信息.结果:患者的年龄为0.8 ~18.0岁,中位数为5.0岁,平均(6.23±3.46)岁,其中男1 649例(52.4%,1 649/3 148),女1 499例(47.6%,1 499/3148).按主要疾病诊断分类为:龋病1 105例(35.1%,1 105/3 148),牙髓根尖周病1 013例(32.2

  4. Short-term antidiabetic treatment with insulin or metformin has a similar impact on the components of metabolic syndrome in women with gestational diabetes mellitus requiring antidiabetic agents: results of a prospective, randomised study.

    Science.gov (United States)

    Zawiejska, A; Wender-Ozegowska, E; Grewling-Szmit, K; Brazert, M; Brazert, J

    2016-04-01

    Gestational diabetes mellitus (GDM) is associated with an increased prevalence of fetal and maternal complications primarily caused by maternal hyperglycemia, which results in abnormal fetal growth. Diet modification is a common first step in the treatment of GDM, followed by antidiabetic pharmacotherapy if this approach fails. Insulin therapy is generally accepted; however, oral hypoglycemic agents have been used in this population. In this prospective, randomised study, we compared maternal metabolic status after treatment with insulin or metformin. Pregnant women (gestational age: ≥ 20 weeks) with GDM requiring medical hypoglycemic treatment were randomly allocated to the Metformin (n = 35) or Insulin (n = 43) Groups. Maternal metabolic status - assessed by glycated hemoglobin (HBA1c) level, glycemic profile, insulin concentration, Homeostatic Model Assessment - Insulin Resistance index, and lipids - was recorded at booking and throughout pregnancy. The characteristics of the study group were: maternal age 33.5 ± 5.9 years, gestational age at baseline 28.5 ± 3.5 weeks, prepregnancy body mass index (BMI) 32.2 ± 3.5 kg/m(2), HbA1c at baseline 5.6 ± 0.6%, and average daily glycemia 5.9 ± 0.6 mmol/dl. Fasting glycemia at term was significantly lower in the Insulin Group but there were no significant differences in mean daily glycemia, HbA1c and BMI at term between the groups. Longitudinally, there was a small but significant increase in BMI and a significant increase in high-density lipoprotein-cholesterol in the Insulin Group and a significant increase in the atherogenic index of plasma (AIP) and a trend towards higher triglycerides in the Metformin Group. Both fasting and average daily glycemia were significantly reduced following treatment in both groups. No such change was evident for HbA1c. In a relative risk analysis, metformin treatment was associated with an insignificant elevated risk of HbA1c, triglycerides and lipid indices falling within the

  5. Highly reproducible, efficient hysteresis-less CH3NH3PbI(3-x)Cl(x) planar hybrid solar cells without requiring heat-treatment.

    Science.gov (United States)

    Heo, Jin Hyuck; Im, Sang Hyuk

    2016-02-07

    CH3NH3PbI(3-x)Cl(x)(MAPbI(3-x)Cl(x)) mixed halide perovskite powder with uniform composition was synthesized via simple solution chemistry, which demonstrates highly reproducible, efficient planar type MAPbI(3-x)Cl(x) mixed halide perovskite solar cells. Pure MAPbI(3-x)Cl(x) mixed halide perovskite powder was synthesized by reacting a 3 : 1 molar ratio of MAI : PbCl2 powder mixture in isopropanol (IPA) solution for 30 min at 60 °C with subsequent repeated centrifugation and washing in IPA. IPA functions as both the reaction medium for the formation of MAPbI(3-x)Cl(x) mixed halide and a selective remover of unreacted MAI and MACl byproducts. Accordingly, we could deposit a pinhole-free dense MAPbI(3-x)Cl(x) mixed halide perovskite film on a TiO2/FTO substrate through a simple one step spin-coating of pure MAPbI(3-x)Cl(x) mixed halide perovskite powder in DMF solution with HI additive, without further long heat-treatment processes. The deposited MAPbI(3-x)Cl(x) mixed halide perovskite film revealed uniform composition throughout the entire area, and the ratio of Cl to I + Cl and I + Cl to Pb was constant at ∼0.03 and ∼1/3, respectively. On the other hand, the conventional MAPbI(3-x)Cl(x) mixed halide perovskite film prepared by the long heat-treatment process had non-uniform composition because the ratio of Cl to I + Cl fluctuated greatly from 0 to 7.2. The average efficiency of planar type MAPbI(3-x)Cl(x) mixed halide perovskite solar cells was 18.65% ± 0.30% and the champion cell had 1.11 V V(oc), 22.1 mA cm(-2) J(sc), 77% F.F., and 18.9% η for forward scan conditions and 1.11 V V(oc), 22.1 mA cm(-2) J(sc), 78% F.F., and 19.1% η for reverse scan conditions. Although the thickness of the MAPbI(3-x)Cl(x) mixed halide perovskite layer varied from ∼500 nm to ∼900 nm, the efficiency was within the range of 18.3%-19.0%.

  6. Quality of Life in Type 2 Diabetes Mellitus Patients Requiring Insulin Treatment in Buenos Aires, Argentina: A Cross-Sectional Study

    Directory of Open Access Journals (Sweden)

    Andres Pichon-Riviere

    2015-07-01

    Full Text Available Background Decision-makers have begun to recognize Health-Related Quality of Life (HRQoL as an important and measurable outcome of healthcare interventions; and HRQoL data is increasingly being used by policy-makers to prioritize health resources. Our objective was to measure HRQoL in a group of Type 2 Diabetes Mellitus (T2DM patients receiving insulin treatment in Buenos Aires, Argentina. Methods We conducted a cross-sectional study of patients with T2DM over 21 years of age, treated with either Neutral Protamine Hagedorn (NPH insulin or Insulin Glargine (IG, who had not changed their baseline schedule in the last 6 months. The recruitment was during 2006–7 in nine private diabetes specialists’ offices in Buenos Aires, Argentina. A standardized diabetes-specific HRQoL questionnaire, the Audit of Diabetes Dependent Quality of Life (ADDQoL, was used. Results A total of 183 patients were included (93 receiving NPH and 90 receiving IG. The mean QoL score was: 0.98 (SD: 0.89 and the diabetes specific QoL was: -1.49 (SD: 0.90. T2DM had a negative impact on HRQoL with a mean Average Weighted Impact (AWI score on QoL of -1.77 (SD: 1.58. The greatest negative impact was observed for domains: ‘worries about the future’, ‘freedom to eat’, ‘living conditions’, ‘sex life’, and ‘family life’. The mean AWI score was -1.71 (SD: 1.48 in patients treated with IG and -1.85 (SD: 1.68 in patients receiving NPH, this difference was not statistically significant. Conclusion The ADDQoL questionnaire is a tool that can be used in Argentina to measure the QoL of patients with diabetes when evaluating diabetes care programs. The scores of QoL in our selected population did not differ from those reported in high-income countries. We expect that the results of this study will increase healthcare providers’ awareness of patients’ perceived QoL and help to overcome the barriers that delay insulin treatment; mainly clinical inertia and patient

  7. Coal and Coalbed Methane Co-Extraction Technology Based on the Ground Movement in the Yangquan Coalfield, China

    Directory of Open Access Journals (Sweden)

    Guozhong Hu

    2015-07-01

    Full Text Available The Yangquan coalfield is one of the typical highly gassy mining areas in China. However, its coal seams are of lower permeability, which are not conductive to coalbed methane (CBM drainage. In this study, based on the theory of the ground movement, we analyzed the principle of coal and CBM coextraction in the Yangquan coalfield, and established the technology system of coal and CBM coextraction which was further implemented in the coal and CBM coextraction in the Yangquan coalfield. The coal and CBM coextraction technologies based on the “pressure-relief and permeability-increase” effect caused by the mining overburden movement can optimally ensure the safe and efficient mining and improve the gas drainage rate. A series of developed coal and CBM coextraction technologies for the Yangquan coalfield were mainly characterized by the high-level gas drainage roadway. This reached a maximum gas drainage amount of 270,000 m3/day for single drainage roadway and a pressure-relief gas drainage rate of >90%. Those technologies significantly improved the gas drainage effect safely and efficiently achieving the coal and CBM coextraction.

  8. Computer technology-based interventions in HIV prevention: state of the evidence and future directions for research

    Science.gov (United States)

    Noar, Seth M.

    2015-01-01

    Computer technology-based interventions (CBIs) represent a promising area for HIV prevention behavioral intervention research. Such programs are a compelling prevention option given their potential for broad reach, customized content, and low cost delivery. The purpose of the current article is to provide a review of the state of the literature on CBIs. First, we define CBIs in HIV prevention and highlight the many advantages of such interventions. Next, we provide an overview of what is currently known regarding the efficacy of CBIs in HIV prevention, focusing on two recent meta-analyses of this literature. Finally, we propose an agenda for future directions for research in the area of CBIs, using the RE-AIM model as an organizing guide. We conclude that with the continued growth of computer technologies, opportunities to apply such technologies in HIV prevention will continue to blossom. Further research is greatly needed to advance an understanding of not only how and under what circumstances CBIs can be efficacious, but also how the reach, adoption, implementation, and maintenance of such programs in clinical and community settings can be achieved. PMID:21287420

  9. Analysis of Web development technology based on Java%基于Java的Web开发技术浅析

    Institute of Scientific and Technical Information of China (English)

    贾文潇; 邓俊杰

    2016-01-01

    随着互联网技术的快速发展和Web技术的广泛应用,使得基于Web技术的应用系统的开发成为了软件开发中的热点.由于Java的可移植性、易用性等特性,再加上完善的Web应用体系结构,基于Java的Web开发技术得到了广泛应用.本文详细阐述了基于Java语言在Web开发,同时简要论述了Web应用的基本原理和基于Java的Web开发技术.%With the rapid development of Internet technology and Web technology widespread application, makes the development of application system based on Web technology become the hotspot in software development.Because the features, such as portability,ease of use of Java plus perfect Web application system structure,development of Java based Web technology has been widely applied.This paper introduced in detail based on Java language in Web development, and briefly discusses the basic principle of Web application and Web development technology based on Java.

  10. 基于GPRS的远程控制技术开发%Development of Remote Control Technology Based On GPRS

    Institute of Scientific and Technical Information of China (English)

    关成斌; 王捷; 邢福成; 孙盛坤

    2011-01-01

    In this paper, with the advantage of data transmission by GPRS, remote control technology was studied based on GPRS, and was used on a self-made car. The experiment results showed that the remote control technology based on GPRS had many advantages, such as real-time, good stability and economy. At last, remote control technology by general communication used on military field was proposed.%分析了采用GPRS进行数据传输的特点和优势,研究了基于GPRS的远程控制技术,并在一个自制的小车上通过了试验.通过试验验证了采用GPRS技术进行远程控制较采用短消息的方法具有实时性高、稳定性好、经济性好的优势.最后,对采用通用通信技术的远程控制技术在军事上的应用进行了展望.

  11. Development of Public Training System for Emergency Exercise Using Virtual Reality Technology Based on Radioactive Release Accident

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byung Il; Park, Seong Jun; Lee, Dewhey; Song, Sub Lee; Park, Younwon [BEES Inc., Daejeon (Korea, Republic of)

    2016-10-15

    An exercise is normally conducted for a day or two days depending on the scale of the exercise. What we have experienced up to date there are several limitations in the radiological emergency exercises such as low public acceptance, poor enthusiasm in the exercise participation, not very attracting exercise scenarios, low efficiency in conducting an exercise, and so on. In order to overcome the limitations of the present exercising system, we would like to develop a radiological emergency exercise system using VR (virtual reality) technology based on a radioactive release accident. In this paper, we just introduce some basic development methods and event tree based scenario as a beginning stage. After the accident in Fukushima Daiichi NPP, the importance of emergency exercise especially for the public is far more emphasized around the world more and more. However, the human labor focused radiological emergency exercise up to now has many limitations. After developing this system properly and by using it, we could even expect to estimate the weak points of the emergency arrangements and strategy we have.

  12. Technology-based management of environmental organizations using an Environmental Management Information System (EMIS): Design and development

    Science.gov (United States)

    Kouziokas, Georgios N.

    2016-01-01

    The adoption of Information and Communication Technologies (ICT) in environmental management has become a significant demand nowadays with the rapid growth of environmental information. This paper presents a prototype Environmental Management Information System (EMIS) that was developed to provide a systematic way of managing environmental data and human resources of an environmental organization. The system was designed using programming languages, a Database Management System (DBMS) and other technologies and programming tools and combines information from the relational database in order to achieve the principal goals of the environmental organization. The developed application can be used to store and elaborate information regarding: human resources data, environmental projects, observations, reports, data about the protected species, environmental measurements of pollutant factors or other kinds of analytical measurements and also the financial data of the organization. Furthermore, the system supports the visualization of spatial data structures by using geographic information systems (GIS) and web mapping technologies. This paper describes this prototype software application, its structure, its functions and how this system can be utilized to facilitate technology-based environmental management and decision-making process.

  13. Entericidin is required for a probiotic treatment (Enterobacter sp. strain C6-6) to protect trout from cold-water disease challenge.

    Science.gov (United States)

    Schubiger, Carla B; Orfe, Lisa H; Sudheesh, Ponnerassery S; Cain, Kenneth D; Shah, Devendra H; Call, Douglas R

    2015-01-01

    Flavobacterium psychrophilum causes bacterial cold-water disease in multiple fish species, including salmonids. An autochthonous Enterobacter strain (C6-6) inhibits the in vitro growth of F. psychrophilum, and when ingested as a putative probiotic, it provides protection against injection challenge with F. psychrophilum in rainbow trout. In this study, low-molecular-mass (≤3 kDa) fractions from both Enterobacter C6-6 and Escherichia coli K-12 culture supernatants inhibited the growth of F. psychrophilum. The ≤3-kDa fraction from Enterobacter C6-6 was analyzed by SDS-PAGE, and subsequent tandem mass spectroscopy identified EcnB, which is a small membrane lipoprotein that is a putative pore-forming toxin. Agar plate diffusion assays demonstrated that ecnAB knockout strains of both Enterobacter C6-6 and E. coli K-12 no longer inhibited F. psychrophilum (P ) and the wild-type strain (C6-6) were added to the fish diet every day for 38 days. On day 11, the fish were challenged by injection with a virulent strain of F. psychrophilum (CSF 259-93). Fish that were fed C6-6 had significantly longer survival than fish fed the ecnAB knockout strain (P Enterobacter C6-6, and it may present new opportunities for therapeutic and prophylactic treatments against similarly susceptible pathogens.

  14. Tratamiento nutricional de la obesidad mórbida que requiere cirugía bariátrica Nutritional treatment of morbid obesity requiring bariatric surgery

    Directory of Open Access Journals (Sweden)

    Miriam Bolet Astoviza

    2009-12-01

    Full Text Available La obesidad en el mundo actual es un importante problema de salud por el riesgo aumentado de morbilidad y mortalidad, sobre todo por las enfermedades cardiovasculares que puede ocasionar. También es un factor de riesgo de diabetes mellitus, hipertensión arterial, enfermedad vesicular, osteoartritis, y ciertos tipos de cánceres, que influyen en la calidad de vida de los pacientes y finalmente limitan su esperanza de vida. En el 95 % de los casos la obesidad es exógena o nutricional, y está asociada a la ingestión de dietas hiperenergéticas y a escasa actividad física. La obesidad se considera mórbida cuando la persona alcanza 40 kg/m2 o más de índice de masa corporal. Se realiza una revisión del tema de la obesidad mórbida y su tratamiento nutricional preoperatorio y posoperatorio.In present era obesity is a significant health problem due to increased risk of morbidity and mortality, mainly by the potential cardiovascular diseases. Also, it is a risk factor of diabetes mellitus, high blood pressure, vesicular disease, osteoarthritis, and some types of cancer influencing in quality of life of patients and it is associated with ingestion of hyperenergetic diets and the lack of physical activity. Obesity is considered as morbid when a person gain 40 kg/m2 or more in the body mass rate. A review on morbid obesity is performed and its preoperative and on the postoperative nutritional treatment.

  15. The emergence of new technology-based industries: the case of fuel cells and its technological relatedness to regional knowledge bases

    DEFF Research Database (Denmark)

    Tanner, Anne Nygaard

    2016-01-01

    to emerging radical technologies that create the foundation for new industries. The article develops a new measure for technological relatedness between the knowledge base of a region and that of a radical technology based on patent classes. It demonstrates that emerging fuel cell technology develops where...... the regional knowledge base is technologically related to that of fuel cells and consequently confirms the evolutionary thesis....

  16. A Meta-Analysis Method to Advance Design of Technology-Based Learning Tool: Combining Qualitative and Quantitative Research to Understand Learning in Relation to Different Technology Features

    Science.gov (United States)

    Zhang, Lin

    2014-01-01

    Educators design and create various technology tools to scaffold students' learning. As more and more technology designs are incorporated into learning, growing attention has been paid to the study of technology-based learning tool. This paper discusses the emerging issues, such as how can learning effectiveness be understood in relation to…

  17. Towards a Socio-Cultural Framework for the Analysis of Joint Student-Teacher Development over Technology-Based Mathematics Lessons

    Science.gov (United States)

    Monaghan, John

    2013-01-01

    This paper offers a framework, an extension of Valsiner's "zone theory", for the analysis of joint student-teacher development over a series of technology-based mathematics lessons. The framework is suitable for developing research studies over a moderately long period of time and considers interrelated student-teacher development as…

  18. Technology-Based Programs to Promote Walking Fluency or Improve Foot-Ground Contact during Walking: Two Case Studies of Adults with Multiple Disabilities

    Science.gov (United States)

    Lancioni, Giulio E.; Singh, Nirbhay N.; O'Reilly, Mark F.; Sigafoos, Jeff; La Martire, Maria L.; Oliva, Doretta; Groeneweg, Jop

    2012-01-01

    These two case studies assessed technology-based programs for promoting walking fluency and improving foot-ground contact during walking with a man and a woman with multiple disabilities, respectively. The man showed breaks during walking and the woman presented with toe walking. The technology used in the studies included a microprocessor with…

  19. Knowledge and Attitudes of Ugandan Preservice Science and Mathematics Teachers toward Global and Ugandan Science--and Technology-Based Problems and/or Threats

    Science.gov (United States)

    Robinson, Michael; Tibanyendera, Basil; Seltzer-Kelly, Debbie

    2007-01-01

    This article reports the effects of a science, technology, and society (STS) teaching approach on the knowledge and attitudes of preservice science and mathematics teachers in Uganda toward global science and technology-based problems and/or threats. The responses of a baseline or control group (N = 50) and an experimental group (N = 50) to five…

  20. Severe neurotoxicity requiring mechanical ventilation in a dog envenomed by a red-bellied black snake (Pseudechis porphyriacus) and successful treatment with an experimental bivalent whole equine IgG antivenom.

    Science.gov (United States)

    Padula, A M; Leister, E M

    2017-09-04

    Snakebite in dogs from Pseudechis porphyriacus (red-bellied black snake; RBBS) is a common envenomation treated by veterinarians in Australia where this snake occurs. This case report describes the successful treatment of a clinically severe RBBS envenomation in a dog with an experimental bivalent equine whole IgG antivenom and mechanical ventilation, following its presentation in a cyanotic state. The cause of the cyanosis and respiratory distress was considered due to paralysis from neurotoxins in RBBS venom. The dog was treated with two vials of bivalent antivenom, each containing sufficient antivenom to neutralise the lethal effects of 40 mg of tiger snake (Notechis sp) and 40 mg of brown snake (Pseudonaja sp) venom. Hypoxaemia (Sp02 of 75%) and hypercapnia (PaCO2 of 61 mmHg) indicated the need for mechanical ventilation (MV) to prevent imminent death. The dog was anaesthetised using total intravenous anaesthesia and MV used for 18 h. Following discontinuation of MV, it resumed spontaneous breathing thereafter and made a complete recovery. Serum biochemistry revealed a significant myopathy with elevated CK and AST levels, peaking approximately 48 h post-treatment. Elevated liver enzymes, suggestive of hypoxic liver injury, were detected during the period of hospitalisation. The dog represented approximately one week after hospital discharge because of inappetence and mild hepatopathy, which resolved spontaneously by 30 d post-treatment. A mild coagulopathy was initially present which resolved within 24 h following antivenom treatment. At initial presentation, RBBS venom antigen was detected by sandwich ELISA in urine and serum. Free RBBS venom antigen was not detected post-antivenom treatment. Human cases of RBBS requiring ventilatory support are rare. This unusual case of RBBS envenomation in a dog highlights its potential clinical severity in dogs, and the need for early, aggressive, MV to achieve a successful outcome in cyanosed and clinically severe cases

  1. The effectiveness of mobile-health technology-based health behaviour change or disease management interventions for health care consumers: a systematic review.

    Science.gov (United States)

    Free, Caroline; Phillips, Gemma; Galli, Leandro; Watson, Louise; Felix, Lambert; Edwards, Phil; Patel, Vikram; Haines, Andy

    2013-01-01

    Mobile technologies could be a powerful media for providing individual level support to health care consumers. We conducted a systematic review to assess the effectiveness of mobile technology interventions delivered to health care consumers. We searched for all controlled trials of mobile technology-based health interventions delivered to health care consumers using MEDLINE, EMBASE, PsycINFO, Global Health, Web of Science, Cochrane Library, UK NHS HTA (Jan 1990-Sept 2010). Two authors extracted data on allocation concealment, allocation sequence, blinding, completeness of follow-up, and measures of effect. We calculated effect estimates and used random effects meta-analysis. We identified 75 trials. Fifty-nine trials investigated the use of mobile technologies to improve disease management and 26 trials investigated their use to change health behaviours. Nearly all trials were conducted in high-income countries. Four trials had a low risk of bias. Two trials of disease management had low risk of bias; in one, antiretroviral (ART) adherence, use of text messages reduced high viral load (>400 copies), with a relative risk (RR) of 0.85 (95% CI 0.72-0.99), but no statistically significant benefit on mortality (RR 0.79 [95% CI 0.47-1.32]). In a second, a PDA based intervention increased scores for perceived self care agency in lung transplant patients. Two trials of health behaviour management had low risk of bias. The pooled effect of text messaging smoking cessation support on biochemically verified smoking cessation was (RR 2.16 [95% CI 1.77-2.62]). Interventions for other conditions showed suggestive benefits in some cases, but the results were not consistent. No evidence of publication bias was demonstrated on visual or statistical examination of the funnel plots for either disease management or health behaviours. To address the limitation of the older search, we also reviewed more recent literature. Text messaging interventions increased adherence to ART and

  2. The effectiveness of mobile-health technology-based health behaviour change or disease management interventions for health care consumers: a systematic review.

    Directory of Open Access Journals (Sweden)

    Caroline Free

    Full Text Available BACKGROUND: Mobile technologies could be a powerful media for providing individual level support to health care consumers. We conducted a systematic review to assess the effectiveness of mobile technology interventions delivered to health care consumers. METHODS AND FINDINGS: We searched for all controlled trials of mobile technology-based health interventions delivered to health care consumers using MEDLINE, EMBASE, PsycINFO, Global Health, Web of Science, Cochrane Library, UK NHS HTA (Jan 1990-Sept 2010. Two authors extracted data on allocation concealment, allocation sequence, blinding, completeness of follow-up, and measures of effect. We calculated effect estimates and used random effects meta-analysis. We identified 75 trials. Fifty-nine trials investigated the use of mobile technologies to improve disease management and 26 trials investigated their use to change health behaviours. Nearly all trials were conducted in high-income countries. Four trials had a low risk of bias. Two trials of disease management had low risk of bias; in one, antiretroviral (ART adherence, use of text messages reduced high viral load (>400 copies, with a relative risk (RR of 0.85 (95% CI 0.72-0.99, but no statistically significant benefit on mortality (RR 0.79 [95% CI 0.47-1.32]. In a second, a PDA based intervention increased scores for perceived self care agency in lung transplant patients. Two trials of health behaviour management had low risk of bias. The pooled effect of text messaging smoking cessation support on biochemically verified smoking cessation was (RR 2.16 [95% CI 1.77-2.62]. Interventions for other conditions showed suggestive benefits in some cases, but the results were not consistent. No evidence of publication bias was demonstrated on visual or statistical examination of the funnel plots for either disease management or health behaviours. To address the limitation of the older search, we also reviewed more recent literature. CONCLUSIONS: Text

  3. Short-Term Efficacy of an Innovative Mobile Phone Technology-Based Intervention for Weight Management for Overweight and Obese Adolescents: Pilot Study.

    Science.gov (United States)

    Chen, Jyu-Lin; Guedes, Claudia M; Cooper, Bruce A; Lung, Audrey E

    2017-08-02

    In the United States, approximately one-third of adolescents are now overweight or obese, and one in six is obese. This financial cost and the larger nonfinancial costs of obesity make obesity prevention and management for adolescents imperative for the health of the nation. However, primary care visits are typically brief, and primary care providers may lack adequate resources to help overweight or obese adolescents to manage weight issues. To augment the efficacy of primary care visits for adolescent weight management, mobile phone technology can be used as an adjunct treatment that provides additional opportunities for encouraging improvement in lifestyle, attainment, and maintenance of healthy weight. The purposes of this study were to (1) measure effects of an innovative mobile phone technology-based intervention for overweight and obese adolescents and to (2) examine the intervention's feasibility for use in primary care clinics. The mobile phone-based intervention had three components: use of the Fitbit Flex, participation in an online educational program, and receipt of biweekly text messages during the maintenance phase. A randomized controlled study design was utilized. Data regarding anthropometrics (body mass index [BMI] and waist-to-hip ratio), blood pressure, levels of physical and sedentary activity, diet, and self-efficacy regarding physical activity and diet were collected at baseline and at 3 and 6 months after the baseline assessment. A total of 40 adolescents participated in the study. At the 6-month follow-up visit, compared to participants in the control group, the mobile phone-based intervention participants had significant improvement in BMI (z=-4.37, P=.001), diastolic blood pressure (z=-3.23, P=.001), physical activity days per week (z=2.58, P=.01), TV and computer time (z=-3.34, P=.001), servings of fruits and vegetables per day (z=2.74, P=.006), servings of soda and sweetened drinks (z=-3.19, P=.001), physical activity self-efficacy (z=2

  4. 基于虾类食品的保鲜保藏技术研究进展%Food preservation technology based on shrimp food

    Institute of Scientific and Technical Information of China (English)

    魏静; 崔峰; 张永进; 王伟; 林琳; 叶应旺; 赖年悦; 姜绍通; 陆剑锋

    2013-01-01

    随着世界渔业的迅速发展,虾类食品的消费与贸易在国际水产品市场上占据着日益重要的地位。我国是世界上最大的虾类食品生产国,也是主要的虾类食品出口国,但与发达国家相比,目前我国的虾类食品生产和加工技术水平仍然较低,尤其是在虾类食品的保鲜、保藏技术方面。因此有必要对虾类食品的各种杀菌技术及其应用进行研究,并总结有效的保鲜、保藏方法。本文综述了传统保藏、化学和生物技术、低温保鲜、加热处理、气调保藏、物理杀菌技术等基于虾类食品的保鲜、保藏技术研究进展,为虾类食品的货架期延长提供一定的理论参考和实践依据。%With the development of the fishing industry in the world , the consumption and trade of shrimp products in the international fish markets occupy an increasingly important position .China is one of the world's largest producer of shrimp products , also a major exporter of shrimp products , but the technical level of China's shrimp production and processing is lower than that of other developed countries , especially in food preservation technology based on shrimp food .Therefore , it's necessary to study the various sterilization technologies and their applications in shrimp food , summarize the effective preservation methods .In this paper, we summarized the progress of the shrimp fresh preservation technology , such as traditional preservation , chemical technology and biotechnology , low-temperature preservation , heat treatment , controlled atmosphere preservation , physical sterilization technologies , in order to provide a theoretical reference and practical basis to extend the shelf life of shrimp products .

  5. An assessment of technology-based service encounters & network security on the e-health care systems of medical centers in Taiwan

    Directory of Open Access Journals (Sweden)

    Chang Ching

    2008-04-01

    Full Text Available Abstract Background Enhancing service efficiency and quality has always been one of the most important factors to heighten competitiveness in the health care service industry. Thus, how to utilize information technology to reduce work load for staff and expeditiously improve work efficiency and healthcare service quality is presently the top priority for every healthcare institution. In this fast changing modern society, e-health care systems are currently the best possible way to achieve enhanced service efficiency and quality under the restraint of healthcare cost control. The electronic medical record system and the online appointment system are the core features in employing e-health care systems in the technology-based service encounters. Methods This study implemented the Service Encounters Evaluation Model, the European Customer Satisfaction Index, the Attribute Model and the Overall Affect Model for model inference. A total of 700 copies of questionnaires from two authoritative southern Taiwan medical centers providing the electronic medical record system and the online appointment system service were distributed, among which 590 valid copies were retrieved with a response rate of 84.3%. We then used SPSS 11.0 and the Linear Structural Relationship Model (LISREL 8.54 to analyze and evaluate the data. Results The findings are as follows: (1 Technology-based service encounters have a positive impact on service quality, but not patient satisfaction; (2 After experiencing technology-based service encounters, the cognition of the service quality has a positive effect on patient satisfaction; and (3 Network security contributes a positive moderating effect on service quality and patient satisfaction. Conclusion It revealed that the impact of electronic workflow (online appointment system service on service quality was greater than electronic facilities (electronic medical record systems in technology-based service encounters. Convenience and

  6. An assessment of technology-based service encounters & network security on the e-health care systems of medical centers in Taiwan.

    Science.gov (United States)

    Chang, Hsin Hsin; Chang, Ching Sheng

    2008-04-17

    Enhancing service efficiency and quality has always been one of the most important factors to heighten competitiveness in the health care service industry. Thus, how to utilize information technology to reduce work load for staff and expeditiously improve work efficiency and healthcare service quality is presently the top priority for every healthcare institution. In this fast changing modern society, e-health care systems are currently the best possible way to achieve enhanced service efficiency and quality under the restraint of healthcare cost control. The electronic medical record system and the online appointment system are the core features in employing e-health care systems in the technology-based service encounters. This study implemented the Service Encounters Evaluation Model, the European Customer Satisfaction Index, the Attribute Model and the Overall Affect Model for model inference. A total of 700 copies of questionnaires from two authoritative southern Taiwan medical centers providing the electronic medical record system and the online appointment system service were distributed, among which 590 valid copies were retrieved with a response rate of 84.3%. We then used SPSS 11.0 and the Linear Structural Relationship Model (LISREL 8.54) to analyze and evaluate the data. The findings are as follows: (1) Technology-based service encounters have a positive impact on service quality, but not patient satisfaction; (2) After experiencing technology-based service encounters, the cognition of the service quality has a positive effect on patient satisfaction; and (3) Network security contributes a positive moderating effect on service quality and patient satisfaction. It revealed that the impact of electronic workflow (online appointment system service) on service quality was greater than electronic facilities (electronic medical record systems) in technology-based service encounters. Convenience and credibility are the most important factors of service quality

  7. Analyzing the Effect of Technology-Based Intervention in Language Laboratory to Improve Listening Skills of First Year Engineering Students

    Directory of Open Access Journals (Sweden)

    Pasupathi Madhumathi

    2013-04-01

    Full Text Available First year students pursuing engineering education face problems with their listening skills. Most of the Indian schools use a bilingual method for teaching subjects from primary school through high school. Nonetheless, students entering university education develop anxiety in listening to classroomlectures in English. This article reports an exploratory study that aimed to find out whether the listening competences of students improved when technology was deployed in language laboratory. It also investigated the opinions of the students about using teacher-suggested websites for acquiring listening skills. The results of the study indicated that the use of technology in a language laboratory for training students in listening competences had reduced the anxiety of the students when listening to English. Further, there was a significant improvement on the part of students in acquiring listening skills through technology-based intervention.Muchos estudiantes de ingeniería de primer año en India tienen problemas con sus habilidades de escucha en inglés; experimentan ansiedad al momento de escuchar conferencias en inglés, pese a que provienen de colegios donde se sigue un modelo bilingüe para enseñar materias desde la primariahasta la secundaria. Con el objetivo de averiguar si las competencias de escucha de los estudiantes mejoran cuando se introduce la tecnología en el laboratorio de idiomas, se realizó un estudio exploratorio en el que se tuvieron en cuenta las opiniones de los estudiantes acerca del uso de sitios web sugeridos por el docente para adquirir habilidades de escucha. Los resultados indican que el uso de la tecnología en el laboratorio de idiomas reduce la ansiedad de los estudiantes al momento de escuchar conferencias en inglés y que progresan significativamente en sus habilidades de escucha.

  8. Measuring Efficiency and Productivity Growth of New Technology-Based Firms in Business Incubators: The Portuguese Case Study of Madan Parque

    Directory of Open Access Journals (Sweden)

    A. Grilo

    2015-01-01

    Full Text Available Business incubators can play a major role in helping to turn a business idea into a technology-based organization that is economically efficient. However, there is a shortage in the literature regarding the efficiency evaluation and productivity evolution of the new technology-based firms (NTBFs in the incubation scope. This study develops a model based on the data envelopment analysis (DEA methodology, which allows the incubated NTBFs to evaluate and improve the efficiency of their management. Moreover, the Malmquist index is used to examine productivity change. The index is decomposed into multiple components to give insights into the root sources of productivity change. The proposed model was applied in a case study with 13 NTBFs incubated. From that study, we conclude that inefficient firms invest excessively in research and development (R&D, and, on average, firms have a productivity growth in the period of study.

  9. Technology-based programs to support forms of leisure engagement and communication for persons with multiple disabilities: two single-case studies.

    Science.gov (United States)

    Lancioni, Giulio E; Singh, Nirbhay N; O'Reilly, Mark F; Green, Vanessa; Oliva, Doretta; Buonocunto, Francesca; Sacco, Valentina; Biancardi, Emma M; Di Nuovo, Santo

    2012-01-01

    To extend the assessment of technology-based programs for promoting stimulus choice and staff/caregiver calls or radio operation and text messaging. In Study I, the program involved a portable computer, commercial software, and a microswitch to allow a man with motor impairment and moderate intellectual disability to choose among preferred stimuli (e.g., songs and film clips) and persons to call. In Study II, the programs involved (a) a radio device and an electronic control unit or (b) a net-book computer and a global system for mobile communication. A woman with blindness and moderate intellectual disability used a microswitch to operate the radio or send and listen to text messages. The participants succeeded in using the technology-aided programs through simple microswitch activations involving partial hand closure (Study I) or hand pressure (Study II). Technology-based programs can provide persons with multiple disabilities relevant leisure and communication opportunities.

  10. Measuring efficiency and productivity growth of new technology-based firms in business incubators: the Portuguese case study of Madan Parque.

    Science.gov (United States)

    Grilo, A; Santos, J

    2015-01-01

    Business incubators can play a major role in helping to turn a business idea into a technology-based organization that is economically efficient. However, there is a shortage in the literature regarding the efficiency evaluation and productivity evolution of the new technology-based firms (NTBFs) in the incubation scope. This study develops a model based on the data envelopment analysis (DEA) methodology, which allows the incubated NTBFs to evaluate and improve the efficiency of their management. Moreover, the Malmquist index is used to examine productivity change. The index is decomposed into multiple components to give insights into the root sources of productivity change. The proposed model was applied in a case study with 13 NTBFs incubated. From that study, we conclude that inefficient firms invest excessively in research and development (R&D), and, on average, firms have a productivity growth in the period of study.

  11. Effectiveness of a Technology-Based Injury Prevention Program for Enhancing Mothers' Knowledge of Child Safety: Protocol for a Randomized Controlled Trial.

    Science.gov (United States)

    Chow, Chun Bong; Wong, Wilfred Hing-Sang; Leung, Wing Cheong; Tang, Mary Hoi-Yin; Chan, Ko Ling; Or, Calvin Kl; Li, Tim Mh; Ho, Frederick Ka Wing; Lo, Daniel; Ip, Patrick

    2016-10-31

    Provision of anticipatory guidance for parents is recommended as an effective strategy to prevent injuries among young children. Technology-based anticipatory guidance has been suggested to reinforce the effectiveness of injury prevention and improve parents' knowledge of child safety. This study aims to examine the effectiveness of a technology-based injury prevention program with parental anticipatory guidance for enhancing mothers' knowledge of child safety. In this randomized controlled trial, 308 mothers will be recruited from the antenatal clinics and postnatal wards of two major public hospitals in Hong Kong. Participating mothers will be randomly assigned into intervention and control groups. Mothers in the intervention group will be given free access to a technology-based injury prevention program with anticipatory guidance, whereas mothers in the control group will be given a relevant booklet on parenting. The injury prevention program, available as a website or on a mobile app, includes behavioral components based on the Theory of Planned Behavior. The primary outcome measure will be the change in the mother's knowledge of child safety. The secondary outcome measures will be age-appropriate domestic safety knowledge, attitudes, intentions, perceived behavioral control, and self-reported behavior related to home safety practice. We will also determine dose-response relationships between the outcome measures and the website and mobile app usage. Enrolment of participants will begin in October 2016. Results are expected by June 2018. Parents will be able to easily access the domestic injury prevention website to find information regarding child injury prevention. It is anticipated that the technology-based intervention will help parents improve their knowledge of child safety and raise their awareness about the consequences of domestic injuries and the importance of prevention. Clinicaltrials.gov Clinicaltrials.gov NCT02835768; http://clinicaltrials.gov/ct2

  12. The success factors in the new technology based firms; Factores de exito en los procesos de reacion de empresas de base tecologica

    Energy Technology Data Exchange (ETDEWEB)

    Merino, C.; Villar, L.

    2007-07-01

    New Technology Based Firms (NTBFs) are taking an important role around competitive strategies inside different administrative frameworks, understanding their value for society and the need based on work plans to support their development. In this case, next lines are focused on conceptual side about NTBFs reality even more an analytical model proposal based on a structure composed by tangible and intangible assets what creating a global vision of entrepreneurial process and main issues what impacting on success rate. (Author) 88 refs.

  13. Osteoporosis treatment

    DEFF Research Database (Denmark)

    Pazianas, Michael; Abrahamsen, Bo

    2016-01-01

    The findings of the Women's Health Initiative study in 2002 marginalized the use of hormone replacement therapy and established bisphosphonates as the first line of treatment for osteoporosis. Denosumab could be used in selected patients. Although bisphosphonates only maintain the structure of bone...... to their benefits/harm ratio. Treatment of osteoporosis is a long process, and many patients will require treatment with more than one type of drug over their lifetime....

  14. 基于复杂数据处理的可视化技术研究%Visualization Technology Base on the Treatment of Complicate Data

    Institute of Scientific and Technical Information of China (English)

    吴英彬; 郭福亮

    2015-01-01

    随着信息化建设的发展,大型管理信息系统中的数据越发复杂多样。如何发现数据及其结构关系,找出数据中隐含的现象,帮助用户理解大量的数据信息,就显得越来越为重要。85%以上单位的决策信息与空间位置相关,但一般仅基于传统 MIS 的方式,以纯粹的数据表格、窗体和简单的曲线来反映系统中的实体信息。因此,研究数据可视化技术并以电子地图、表格、树图、网络图、多维形状图等形式,将所有与空间位置有关的信息标注在电子地图上,直观形象表述系统的实体,便于理解各种复杂信息,提高效率。%With the development of informational construction ,the data in large management information system are getting more and more complex and diverse .How to find the data and the structural relationship ,find the hidden phenome-non in the data ,help users to understand the large amount of data information ,are more and more important .There are more than 85% of units whose information of decisions are related to spatial position ,but they generally only based on the traditional MIS mode ,reflect system entity information only by data tables ,forms and simple curves .The technology of data visualization can mark all the position-related information on the electronic map base on the electronic maps ,tables ,tree charts ,network diagrams ,multidimensional shape maps and so on ,express the system entity more vividly ,so that the users can understand all kind of complex information easily ,and improve the efficiency .

  15. 中国与印度“大火规”水处理系统的设计要求对比%Comparison Chinese with India Design Requirement of Water Treatment System in Power Plant Code

    Institute of Scientific and Technical Information of China (English)

    徐淑姣

    2015-01-01

    国内电力设计行业涉足印度发电工程日益增多。本文对比了中印电力标准中水处理系统的设计要求,对两国工程设计标准的异同进行了总结,为国内后续开展的印度发电工程水处理系统设计提供参考和借鉴。%More and more Indian power plant projects are designed by Chinese electric power design institute. This paper coMPared the design requirement of water treatment system in power plant code between China and India, and it summarized the differences and similarities in design code of the two countries. It is hoped that the coMParison will provide reference for Chinese to design water treatment system of Indian power plant in the future.

  16. Comparison of the Effects of Pioglitazone versus Placebo when Given in Addition to Standard Insulin Treatment in Patients with Type 2 Diabetes Mellitus Requiring Hemodialysis: Results from the PIOren Study

    Directory of Open Access Journals (Sweden)

    Jan Galle

    2012-05-01

    Full Text Available Background: Patients with type 2 diabetes mellitus and advanced kidney disease are usually treated with insulin. However, the prolonged pharmacokinetic insulin profile in patients with delayed renal insulin elimination impairs a successful therapy. Due to its hepatic metabolism, pioglitazone is a potential candidate for additional administration. The aim of this study was to investigate the effect of pioglitazone versus placebo on total daily insulin requirements and several pleiotropic factors in type 2 diabetes patients requiring hemodialysis. Methods: The effect of pioglitazone (30 mg versus placebo was explored in this prospective, randomized, double-blind parallel multicenter phase II study analyzing data from 36 patients with type 2 diabetes mellitus currently under hemodialysis (25 male, 11 female, aged 69.2 ± 7.9 years, baseline HbA1c 7.6 ± 0.9%. The most important efficacy parameters collected before dialysis and after an overnight fast at baseline and after 6 months were: total daily insulin dose, HbA1c, fasting blood glucose, adiponectin, HDL, LDL, triglycerides, NT-proBNP, and ultrafiltrate volume. Results: Application of pioglitazone resulted in a significant decrease of the daily insulin dose by 35% versus baseline (placebo: –10%, n.s., improvement in HbA1c (–0.60 ± 0.87%, p = 0.015; placebo: 0.21 ± 1.1%, n.s. and adiponectin (7.33 ± 4.80 mg/l, p Conclusions: Addition of pioglitazone to insulin in patients with late-stage kidney failure requiring hemodialysis is a well-tolerated treatment option that improves glycemic control with simultaneous insulin-sparing potential.

  17. Using Information Technology Based Exercises in Primary Mathematics Teaching of Children with Cerebral Palsy and Mental Retardation: A Case Study

    Science.gov (United States)

    Reis, M. G. A. D.; Cabral, L.; Peres, E.; Bessa, M.; Valente, A.; Morais, R.; Soares, S.; Baptista, J.; Aires, A.; Escola, J. J.; Bulas-Cruz, J. A.; Reis, M. J. C. S.

    2010-01-01

    Technology has profoundly changed the way we learn and live. Indeed, such relationship appears to be quite complex, within IT contexts, and especially in socially and technologically rich learning environments, where related skills and learning are progressively required and fostered. Thus, if a satisfactory level of intellectual performance and…

  18. Radiation oncology--linking technology and biology in the treatment of cancer.

    Science.gov (United States)

    Coleman, C Norman

    2002-01-01

    Technical advances in radiation oncology including CT-simulation, 3D- conformal and intensity-modulated radiation therapy (IMRT) delivery techniques, and brachytherapy have allowed greater treatment precision and dose escalation. The ability to intensify treatment requires the identification of the critical targets within the treatment field, recognizing the unique biology of tumor, stroma and normal tissue. Precision is technology based while accuracy is biologically based. Therefore, the intensity of IMRT will undoubtedly mean an increase in both irradiation dose and the use of biological agents, the latter considered in the broadest sense. Radiation oncology has the potential and the opportunity to provide major contributions to the linkage between molecular and functional imaging, molecular profiling and novel therapeutics for the emerging molecular targets for cancer treatment. This process of 'credentialing' of molecular targets will require multi disciplinary imaging teams, clinicians and basic scientists. Future advances will depend on the appropriate integration of biology into the training of residents, continuing post graduate education, participation in innovative clinical research and commitment to the support of basic research as an essential component of the practice of radiation oncology.

  19. Acquiring Knowledge in Learning Concepts from Electrical Circuits: The Use of Multiple Representations in Technology-Based Learning Environments

    Directory of Open Access Journals (Sweden)

    Abdeljalil Métioui

    2012-04-01

    Full Text Available The constructivists approach on the conception of relative software of modelling to training and teaching of the concepts of current and voltage requires appraisal of several disciplinary fields in order to provide to the learners a training adapted to their representations. Thus, this approach requires the researchers to have adequate knowledge or skills in data processing, didactics and science content. In this regard, several researches underline that the acquisition of basic concepts that span a field of a given knowledge, must take into account the student and the scientific representations. The present research appears in this perspective, and aims to present the interactive computer environments that take into account the students (secondary and college and scientific representations related to simple electric circuits. These computer environments will help the students to analyze the functions of the electric circuits adequately.

  20. Space Applications of Automation, Robotics and Machine Intelligence Systems (ARAMIS), phase 2. Volume 1: Telepresence technology base development

    Science.gov (United States)

    Akin, D. L.; Minsky, M. L.; Thiel, E. D.; Kurtzman, C. R.

    1983-01-01

    The field of telepresence is defined, and overviews of those capabilities that are now available, and those that will be required to support a NASA telepresence effort are provided. Investigation of NASA's plans and goals with regard to telepresence, extensive literature search for materials relating to relevant technologies, a description of these technologies and their state of the art, and projections for advances in these technologies over the next decade are included. Several space projects are examined in detail to determine what capabilities are required of a telepresence system in order to accomplish various tasks, such as servicing and assembly. The key operational and technological areas are identified, conclusions and recommendations are made for further research, and an example developmental program is presented, leading to an operational telepresence servicer.

  1. Acquiring Knowledge in Learning Concepts from Electrical Circuits: The Use of Multiple Representations in Technology-Based Learning Environments

    Directory of Open Access Journals (Sweden)

    Abdeljalil Métioui

    2012-04-01

    Full Text Available The constructivists approach on the conception of relative software of modelling to training and teaching of the concepts of current and voltage requires appraisal of several disciplinary fields in order to provide to the learners a training adapted to their representations. Thus, this approach requires the researchers to have adequate knowledge or skills in data processing, didactics and science content. In this regard, several researches underline that the acquisition of basic concepts that span a field of a given knowledge, must take into account the student and the scientific representations. The present research appears in this perspective, and aims to present the interactive computer environments that take into account the students (secondary and college and scientific representations related to simple electric circuits. These computer environments will help the students to analyze the functions of the electric circuits adequately.

  2. Research of RS Decoding Technology Based on GPU%基于GPU的RS译码处理技术研究

    Institute of Scientific and Technical Information of China (English)

    顾久祥; 杨仁忠; 韦宏卫

    2013-01-01

    在分析高速译码处理技术的基础上,提出了基于GPU平台RS译码的解决方案,并基于CUDA编程环境完成了RS译码处理的研究与实现.经测试表明,本文基于GPU的RS译码处理模块在理论纠错范围内的处理速度达900Mbps以上,满足实际遥感信道的译码要求.%In this paper, A RS decoding solution based on GPU platform is proposed, we investigated decoding implementation of RS codes on CUDA. Experimental results show that the processing speed is more than 600Mbps, which can achieve throughput requirement of the remote sensing channel decoding requirements.

  3. Improved fiber-optic link for the phase reference distribution system for the TESLA technology based projects

    Science.gov (United States)

    Czuba, Krzysztof; Felber, Matthias

    2005-09-01

    The UV Free-Electron Laser (UVFEL) [1], The X-Ray Free-Electron Laser (XFEL) [2] and The International Linear Accelerator (ILC) [9] projects will require phase synchronization of various RF frequency subsystems on kilometer distances with accuracy better than 1ps. To fulfill these requirements, a phase reference distribution system concept was proposed and a prototype was developed for tests in the TESLA Test Facility 2 (TTF2). An important part of the phase reference system is the fiber-optic phase stable, long distance link described in this paper. An interferometrical scheme with feedback on phase, suppressing long term phase drifts induced by temperature changes was developed and tested in laboratory and under accelerator conditions. A motorized optical delay line was used in the system to compensate for phase errors. Described are error considerations and most important project issues like the hardware development and the real time phase controller software. The presented measurement results satisfy the design requirements. Experience gained during the experiments yielded proposals for system improvements.

  4. Entrepreneurs in developing a technology based company. The challenge of the case Dynakin; Emprendedoras en el desarrollo de una empresa de base technologica. El desafio del caso Dynakin

    Energy Technology Data Exchange (ETDEWEB)

    Guerrero, M.; Gonzalez, J. L.; Pena, I.

    2012-11-01

    An emerging area of interest for academics, entrepreneurs and policy makers is the analysis and understanding of how and where women entrepreneurs have made differences. Our case study, for example, focuses on women in academic environments who are creating new businesses based on the exploration and exploitation of entrepreneurial opportunities identified in their research activities. Adopting the feminist perspective, our paper tries to identify the opportunities and the challenges faced by women entrepreneurs during the creation process of a technology based enterprise within a university. (Author) 25 refs.

  5. The Research of FTTH ONU Authentication Technology Based on CNR and LDAP%基于CNR及LDAP的光纤到户ONU认证技术的研究

    Institute of Scientific and Technical Information of China (English)

    郭浩; 张华锋

    2015-01-01

    本文论述了基于CNR及LDAP的光纤到户ONU认证技术,该技术实现了光纤到户网络同HFC网络认证系统的统一,是光纤到户网络快速部署、业务快速开通的基础。%The FTTH ONU authentication technology based on CNR and LDAP achieves the unity of the authentication system for the FTTH network and the HFC network. It is the basis for the rapid deployment of FTTH network and Implementation of service.

  6. In-house R&D versus external technology acquisitions : small technology-based firms in the U.S. and Japan

    OpenAIRE

    Kurokawa, Susumu

    1992-01-01

    This research is an investigation of the relationship between in-house R&D and external technology acquisitions--e.g.,licensing,R&D contracts,collaborative R&D projects,joint ventures or mergers--based on the data derived from small technology-based firms in the U.S. and Japan. There are three major parts to this research.In Part 1. we discuss the advantages and disadvantages of in-house R&D versus external technology acquisitions,and examine key factors which affect "make-or-buy. decisions i...

  7. Survey of a community-based infusion program for Australian patients with rheumatoid arthritis requiring treatment with tocilizumab: patient characteristics and drivers of patient satisfaction and patient-perceived benefits and concerns

    Directory of Open Access Journals (Sweden)

    Voight L

    2012-04-01

    Full Text Available Louisa VoightCoast Joint Care, Maroochydore, Queensland, AustraliaBackground: Tocilizumab is an effective therapy for patients with moderate to severe rheumatoid arthritis that is administered by infusion over one hour every 4 weeks. The community-based infusion (ACTiv program was introduced to Australia in August 2010 to provide accessible and convenient treatment for patients with rheumatoid arthritis who require tocilizumab. The primary objectives of this study were to determine the characteristics of patients in the ACTiv program, patient satisfaction, and patient-perceived benefits and concerns with the ACTiv program, and drivers of patient satisfaction and patient-perceived benefits and concerns.Methods: A voluntary self-administered survey was given to all 608 patients in the ACTiv program between January 27, 2011 and March 31, 2011.Results: A total of 351 surveys were returned completed, giving a response rate of 58% (351/608. Most patients in the ACTiv program were women aged 40–64 years, with a mean disease duration of 13.7 years and moderate disability, who had been in the ACTiv program for ≥5 months. Most patients (88%, 302/342 were either very satisfied or satisfied with the ACTiv program and believed that they were very unlikely or somewhat unlikely to switch from the ACTiv program (64%, 214/335. The most important benefit was the reassurance of receiving treatment from a trained nurse in a professional medical environment (33%, 102/309. The most important concern was the fear of side effects (48%, 134/280. The main drivers of patient satisfaction and patient-perceived benefits and concerns of patients were health profile, previous medication experience, and length of treatment time in the program.Conclusion: The ACTiv program is used by patients of various ages, family life situations, and locations. Patient satisfaction with the program is high, which enables patients to benefit from long-term use of tocilizumab

  8. Review of Ship Surveillance Technologies Based on High-Resolution Wide-Swath Synthetic Aperture Radar Imaging

    Directory of Open Access Journals (Sweden)

    Xing Xiang-wei

    2015-02-01

    Full Text Available Synthetic Aperture Radar (SAR is widely used in ship surveillance. High-Resolution Wide-Swath (HRWS SAR data are simultaneously collected, which introduces challenges and offers new research opportunities. SAR-based ship-surveillance technologies and the performance requirements of SAR systems are reviewed and summarized. Furthermore, the characteristics of HRWS SAR imaging and ship surveillance technologies are considered in tandem, and preliminary research results on ship detection, feature extraction, and classification are discussed. Finally, we point out issues to be addressed in future work.

  9. Research on Neutral Point Drifting Technology Based on the Same Harmonic Distribution of Line Voltage%基于相同线电压谐波频带的中性点漂移技术仿真研究

    Institute of Scientific and Technical Information of China (English)

    徐振; 罗仁俊; 黄欢; 钟强; 陈志新

    2011-01-01

    提出了一种基于相同线电压谐波频带的中性点漂移技术。该方法通过对载波相移角度和频率调制比等参数的优化,实现了3个线电压的高次谐波频带保持一致。与常规的故障功率单元处理方法相比,该方法能增加输出线电压的幅值,同时能减少其总谐波含量(Total Harmonic Distortion,THD)。通过仿真验证了该方法的有效性。%Neutral point drifting technology based on the same harmonic distribution of line voltage is proposed.With the optimization of carrier phase-shifted angle and frequency modulation ratio,the harmonic distribution of three line voltages can be consistent.Comparing with the normal failure power unit treatment,the amplitude of output voltage can be increased and THD(Total Harmonic Distortion) can be decreased.Simulation results verify the validity of the proposed method.

  10. IMPROVEMENT OF KEY PROCESSES THROUGH THE ANALYSIS OF VALUE ADDED IN TECHNOLOGY- BASED COMPANIES A SINGLE PROJECT PRODUCTIONS OF THE WATER SECTOR IN CUBA

    Directory of Open Access Journals (Sweden)

    Reina Maylín, Hernández Oro

    2012-01-01

    Full Text Available In this paper, we present the main results of research designed to improve key business processes, using a procedure designed for this purpose, and which includes among its main stages, the analysis of value added by activity, adapting to technology based companies’ productions by one of the water sector project in Cuba. The procedure consistently combines different techniques such as multi-criteria decision analysis for selection of the key processes and analysis of value added by activity to identify key processes to improve and identify opportunities for improvement. The main results are able to identify, classify and relate the processes taking place in the organization, and represent them in a process map, and then determine the key processes for improvement, based on the analysis of value added at each process of each of the activities in it. Derived from the results obtained are proposed and implemented a set of organizational improvements had a positive economic impact for the company under study, allowing a positive conclusion on the feasibility of implementation, flexibility and robustness of the procedure developed in technology-based companies single project productions of the water sector in Cuba to support their business management.

  11. Psycho-physical perfection of economic specialties’ girl students under influence of sport-oriented technology, based on prevalence of volleyball practicing

    Directory of Open Access Journals (Sweden)

    Salatenko I.O.

    2015-12-01

    Full Text Available Purpose: to work out content of sport-oriented technology of physical education, based on prevalence of volleyball practicing. Material: in the research two experimental (n=25, n=25 and one control (n=25 groups of girl students participated. The content of sport-oriented technology, based on prevalence of volleyball practicing included additionally elements of fitness. студенток. Quickness of mental processes and efficiency of mind operations were assessed with the help of special cards, on which 9 dials with pointers were depicted. The sense of test was: addition of dials’ readings in mind; simultaneous calculation of value of scale one division; keeping in memory the previous sum of readings. This task was to be fulfilled for 6 minutes. Results: it was found that quickness of mental processes and mind operations as well as operative memory were at level below average. The most expressed positive factor was registered in group in which circle sport trainings were conducted. It was also found that over-fatigue at the end of academic year influences on testing indicators. Conclusions: the offered by us sport-oriented technology, based on prevalence of volleyball practicing can be recommended as effective mean of economic specialties girl students’ psycho-physical qualities’ strengthening.

  12. 基于泵变频调速的航天器热控制技术%Spacecraft Thermal Control Technology Based on Variable Frequency Pump

    Institute of Scientific and Technical Information of China (English)

    宁献文; 张加迅

    2011-01-01

    文章针对某单相流体回路地面原理样机,提出采用泵变频调速技术进行控温,并对系统控温特性进行了地面试验研究,整个瞬态试验过程中控温精度一般都在士0.3℃以内,最大波动也基本不超过±0.5℃,基于泵变频调速技术的热控制策略性能优良、有效,试验结果可供实际工程设计参考.%The traditional temperature control mode using temperature-sensing valve has three deficiencies with the reliability, dynamic behavior, pump operational efficiency. In order to solve these problems, a new thermal control technology based on variable frequency pump was put forward for a fluid loop prototype model. The temperature control performance of the thermal control technology based on variable frequency pump was tested. During all transients, the controlled temperature was within the range of ±0. 3℃ around the set-point, with a maximum admissible variation range of ±0.5℃. Thermal control strategy based on variable frequency pump has effective performance.

  13. A Study on the Data Compression Technology-Based Intelligent Data Acquisition (IDAQ System for Structural Health Monitoring of Civil Structures

    Directory of Open Access Journals (Sweden)

    Gwanghee Heo

    2017-07-01

    Full Text Available In this paper, a data compression technology-based intelligent data acquisition (IDAQ system was developed for structural health monitoring of civil structures, and its validity was tested using random signals (El-Centro seismic waveform. The IDAQ system was structured to include a high-performance CPU with large dynamic memory for multi-input and output in a radio frequency (RF manner. In addition, the embedded software technology (EST has been applied to it to implement diverse logics needed in the process of acquiring, processing and transmitting data. In order to utilize IDAQ system for the structural health monitoring of civil structures, this study developed an artificial filter bank by which structural dynamic responses (acceleration were efficiently acquired, and also optimized it on the random El-Centro seismic waveform. All techniques developed in this study have been embedded to our system. The data compression technology-based IDAQ system was proven valid in acquiring valid signals in a compressed size.

  14. 基于物联网技术的校园监控技术研究%Research on the Campus Monitoring Technology Based on the Networking Technology

    Institute of Scientific and Technical Information of China (English)

    王新艳

    2015-01-01

    This paper made research on the campus monitoring technology based on the networking technology.In terms of the practical application of the RFID technology,ZigBee technology,wireless sensor network technology,networking technology in the main campus monitoring system,it elaborated the specific technical measures to realize the campus monitoring,hoping to provide some reference and suggestions on the application of the campus monitoring technology based on the networking technol-ogy.%本文对物联网技术的校园监控技术研究,就 RFID 技术、ZigBee 技术、无线传感器网络技术等物联网技术在校园监控系统中的实际应用为主,阐述了实现校园监控的具体技术措施应用方法,希望能够为物联网技术在校园监控系统中的应用提供一些参考和建议。

  15. Energy requirements of adult cats.

    Science.gov (United States)

    Bermingham, Emma N; Thomas, David G; Morris, Penelope J; Hawthorne, Amanda J

    2010-04-01

    A meta-analysis was carried out in order to establish the energy requirements of adult cats. Publications that identified cat body weight (BW) were used to generate allometric relationships between energy requirements and BW of healthy adult cats, using log-log linear regression. Energy requirements were expressed in kcal/kg BW to be consistent with those reported by the National Research Council. Mean maintenance energy requirements were 55.1 (se 1.2) kcal/kg BW (115 treatment groups). Three allometric equations were identified to predict the energy requirements for maintenance of BW in the cat based on BW: light (53.7 kcal/kg BW- 1.061), normal (46.8 kcal/kg BW- 1.115) and heavy (131.8 kcal/kg BW- 0 .366). When reported on lean mass, the allometric equation revealed maintenance requirements were 58.4 kcal/kg lean mass- 1.140 (adjusted R2 0.694; thirty-six treatment groups). The present review suggests that values for maintenance energy requirements based on BW alone may not be an accurate prediction and more detailed information on the age, sex and neuter status, BW and composition would enhance the ability to interpret the maintenance energy requirements of cats.

  16. Sewage Treatment

    Science.gov (United States)

    1976-01-01

    A million gallon-a-day sewage treatment plant in Huntington Beach, CA converts solid sewage to activated carbon which then treats incoming waste water. The plant is scaled up 100 times from a mobile unit NASA installed a year ago; another 100-fold scale-up will be required if technique is employed for widespread urban sewage treatment. This unique sewage-plant employed a serendipitous outgrowth of a need to manufacture activated carbon for rocket engine insulation. The process already exceeds new Environmental Protection Agency Standards Capital costs by 25% compared with conventional secondary treatment plants.

  17. Comparative study of municipal solid waste treatment technologies using life cycle assessment method

    Energy Technology Data Exchange (ETDEWEB)

    Zaman, A.U. [KTH (Sweden). Environmental Engineering and Sustainable Infrastructure

    2010-04-01

    The aim of the study is to analyze three different waste treatment technologies by life cycle assessment tool. Sanitary landfill, incineration and gasification-pyrolysis of the waste treatment technologies are studied in SimaPro software based on input-output materials flow. SimaPro software has been applied for analyzing environmental burden by different impact categories. All technologies are favorable to abiotic and ozone layer depletion due to energy recovery from the waste treatment facilities. Sanitary landfill has the significantly lower environmental impact among other thermal treatment while gases are used for fuel with control emission environment. However, sanitary landfill has significant impact on photochemical oxidation, global warming and acidification. Among thermal technology, pyrolysis-gasification is comparatively more favorable to environment than incineration in global warming, acidification, eutrophication and eco-toxicity categories. Landfill with energy recovery facilities is environmentally favorable. However, due to large land requirement, difficult emission control system and long time span, restriction on land filling is applying more in the developed countries. Pyrolysis-gasification is more environmental friendly technology than incineration due to higher energy recovery efficiency. Life cycle assessment is an effective tool to analyze waste treatment technology based on environmental performances.

  18. 40 CFR 141.130 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... treatment technique requirements for disinfection byproduct precursors in § 141.135. (2) The regulations in... established MCLs for TTHM and HAA5 and treatment technique requirements for disinfection byproduct precursors..., distribution line breaks, storm run-off events, source water contamination events, or cross-connection events....

  19. Ultra-High Voltage DC Convertor Station Equipment Condition Data Access Technology Based on multi-Source Heterogeneous Fusion

    Science.gov (United States)

    Wang, Feng; Zhang, Bo-wen; Han, Shuai; Ren, Wei; Xu, Hai-jun; Fu, Long-ming

    2017-07-01

    With the large-scale construction of special high-voltage project, as well as power supply reliability, security, economic and other increasingly demanding, state monitoring equipment involved in more and more monitoring projects and more and more monitoring data, because these data exist in multiple isolated systems in the Ultra-High Voltage(UHV) AC-DC substation, there is no data sharing mechanism, so a holistic analysis, application and sharing approach for the data set will need a deep consideration. In this paper, the equipment condition monitoring system frame of the UHV converter station and the scheme of the equipment state data access of UHV converter station based on the multi-source and heterogeneous data fusion are presented. Then, data exchange technology of UHV equipment state early warning center was introduced, and a data access and conversion device in the Zhongzhou converter station was deployed to solve the timeliness and functionality difficult of the existing system to meet the requirements of UHV operation and maintenance support.

  20. ONU Configuration Management Technology Based on NGPON System%基于NGPON系统的ONU配置管理技术

    Institute of Scientific and Technical Information of China (English)

    肖青; 黄婷熙

    2012-01-01

    According to ONU property introduced by the China Telecom equipment technical requirements of EPON V2.1, the ONU configuration management technology of NCPON system is proposed. In this paper, the implementation process of traditional ONU configuration management technology and ONU capability set configuration management are introduced. The method can well solve the equipment interworking problems, manage various types of ONU, and has strong practical value.%根据中国电信EPON设备技术要求V2.1中介绍的ONU能力属性,提出NGPON系统中ONU配置管理技术.详细介绍了传统ONU配置管理技术以及ONU能力集配置管理技术实现过程.该方法能很好地解决设备间的互通问题,能很好地管理厂商生产的各种类型ONU,具有很强的实用价值.

  1. Pilot-scale development of new 2G BTL technologies based on gasification and pyrolysis - 2G BIOFUELS 2020

    Energy Technology Data Exchange (ETDEWEB)

    Kurkela, E. [VTT Technical Research Centre of Finland, Espoo (Finland)], email: esa.kurkela@vtt.fi

    2012-07-01

    Finland is committed in reducing emissions of greenhouse gases from transportation. Public financial support is required for demonstration of biofuel production concepts, which has been developed by industry. The present project will develop and pilot new process alternatives, which aim in reducing production costs of biofuels. This is achieved through the development of unit operations by increasing their efficiency and reducing both their operating and investment costs. The project is focused on two alternative thermochemical conversion pathways for the production of wood-based transportations fuels. The main objective in the gasification R and D is to develop alternative gasification-based production technologies which will have maximum overall biomass utilisation efficiency, lower capital costs than present industrially piloted technologies and which can be realised in intermediate size range and are consequently suitable to be fully integrated to forest industries and/or district heating. The main objective in fast pyrolysis R and D is to upgrade fuel quality of bio-oil in a manner making it possible to replace light fuel oil in existing or slightly modified boilers, power plant engines, and eventually to co-feed it into mineral oil refineries. Currently a low pH (causing a need to use acid resistant materials in production, storage, and use) and relative instability (which during long storage cause increase in viscosity) of bio-oil prevent higher-value uses.

  2. Maintaining Cognitive Functioning in Healthy Seniors with a Technology-Based Foreign Language Program: A Pilot Feasibility Study.

    Science.gov (United States)

    Ware, Caitlin; Damnee, Souad; Djabelkhir, Leila; Cristancho, Victoria; Wu, Ya-Huei; Benovici, Judith; Pino, Maribel; Rigaud, Anne-Sophie

    2017-01-01

    Researchers have hypothesized that learning a foreign language could be beneficial for seniors, as language learning requires the use of extensive neural networks. We developed and qualitatively evaluated an English training program for older French adults; our principal objective was to determine whether a program integrating technology is feasible for this population. We conducted a 4-month pilot study (16, 2-h sessions) with 14 French participants, (nine women, five men, average age 75). Questionnaires were administered pre- and post-intervention to measure cognitive level and subjective feelings of loneliness or social isolation; however, these scores did not improve significantly. Post-intervention, semi-directive interviews were carried out with participants, and a content/theme analysis was performed. Five main themes were identified from the interviews: Associations with school, attitudes toward English, motivation for learning English, attitudes toward the program's organization, and social ties. The program was found to be feasible for this age group, yet perceived as quite difficult for participants who lacked experience with English. Nonetheless, most participants found the program to be stimulating and enjoyable. We discuss different suggestions for future programs and future directions for foreign-language learning as a therapeutic and cognitive intervention.

  3. Groupware requirements evolution patterns

    NARCIS (Netherlands)

    Pumareja, Dulce Trinidad

    2013-01-01

    Requirements evolution is a generally known problem in software development. Requirements are known to change all throughout a system's lifecycle. Nevertheless, requirements evolution is a poorly understood phenomenon. Most studies on requirements evolution focus on changes to written specifications

  4. New Type of Touchpad Technology Based on PSD%基于PSD的新型触摸板技术

    Institute of Scientific and Technical Information of China (English)

    赵爱玲; 王丙军; 侯君; 李风雷

    2011-01-01

    In order to meet the big screen display's requirements on touchpad and overcome the disadvantages of interactive touchpad on property and cost, a new type of touchpad technology was invented which was an application of optical system imaging principle as well as optical sensing device of PSD. The infrared spotlight source of contact point of touch pen and touch board imaging on the optical sensor through simple optical system consisted of optical lens and the location of the touch point will be determined by data processing such as coordinates correction. The low cost, easy integration, high sensitivity, high speed of data processing and simple system structure of the new touchpad can be applied to the big size and proportion of the touchpad.%为满足大屏幕显示对触摸板的要求,克服现有交互式触摸板系统在性能及成本方面的不足,设计了一种应用光学系统成像原理和基于光学敏感器件PSD的新型触摸板.将触摸笔与触摸板接触点的红外点光源,通过透镜等组成的简单光学系统,成像于光学传感器,经过坐标校正等数据处理确定触摸点位置.系统设计结构简单紧凑、易于集成,具有很高的数据处理速度,灵敏度高,成本低,尤其适用于大尺寸、大面积触摸板的应用.

  5. Development of Lentivirus-Based Reference Materials for Ebola Virus Nucleic Acid Amplification Technology-Based Assays.

    Science.gov (United States)

    Mattiuzzo, Giada; Ashall, James; Doris, Kathryn S; MacLellan-Gibson, Kirsty; Nicolson, Carolyn; Wilkinson, Dianna E; Harvey, Ruth; Almond, Neil; Anderson, Robert; Efstathiou, Stacey; Minor, Philip D; Page, Mark

    2015-01-01

    The 2013-present Ebola virus outbreak in Western Africa has prompted the production of many diagnostic assays, mostly based on nucleic acid amplification technologies (NAT). The calibration and performance assessment of established assays and those under evaluation requires reference materials that can be used in parallel with the clinical sample to standardise or control for every step of the procedure, from extraction to the final qualitative/quantitative result. We have developed safe and stable Ebola virus RNA reference materials by encapsidating anti sense viral RNA into HIV-1-like particles. The lentiviral particles are replication-deficient and non-infectious due to the lack of HIV-1 genes and Envelope protein. Ebola virus genes were subcloned for encapsidation into two lentiviral preparations, one containing NP-VP35-GP and the other VP40 and L RNA. Each reference material was formulated as a high-titre standard for use as a calibrator for secondary or internal standards, and a 10,000-fold lower titre preparation to serve as an in-run control. The preparations have been freeze-dried to maximise stability. These HIV-Ebola virus RNA reference materials were suitable for use with in-house and commercial quantitative RT-PCR assays and with digital RT-PCR. The HIV-Ebola virus RNA reference materials are stable at up to 37°C for two weeks, allowing the shipment of the material worldwide at ambient temperature. These results support further evaluation of the HIV-Ebola virus RNA reference materials as part of an International collaborative study for the establishment of the 1st International Standard for Ebola virus RNA.

  6. Information Technology-Based Interventions to Improve Drug-Drug Interaction Outcomes: A Systematic Review on Features and Effects.

    Science.gov (United States)

    Nabovati, Ehsan; Vakili-Arki, Hasan; Taherzadeh, Zhila; Saberi, Mohammad Reza; Medlock, Stephanie; Abu-Hanna, Ameen; Eslami, Saeid

    2017-01-01

    The purpose of this systematic review was to identify features and effects of information technology (IT)-based interventions on outcomes related to drug-drug interactions (DDI outcomes). A literature search was conducted in Medline, EMBASE, and the Cochrane Library for published English-language studies. Studies were included if a main outcome was related to DDIs, the intervention involved an IT-based system, and the study design was experimental or observational with controls. Study characteristics, including features and effects of IT-based interventions, were extracted. Nineteen studies comprising five randomized controlled trials (RCT), five non-randomized controlled trials (NRCT) and nine observational studies with controls (OWC) were included. Sixty-four percent of prescriber-directed interventions, and all non-prescriber interventions, were effective. Each of the following characteristics corresponded to groups of studies of which a majority were effective: automatic provision of recommendations within the providers' workflow, intervention at the time of decision-making, integration into other systems, and requiring the reason for not following the recommendations. Only two studies measured clinical outcomes: an RCT that showed no significant improvement and an OWC that showed improvement, but did not statistically assess the effect. Most studies that measured surrogate outcomes (e.g. potential DDIs) and other outcomes (e.g. adherence to alerts) showed improvements. IT-based interventions improve surrogate clinical outcomes and adherence to DDI alerts. However, there is lack of robust evidence about their effectiveness on clinical outcomes. It is recommended that researchers consider the identified features of effective interventions in the design of interventions and evaluate the effectiveness on DDI outcomes, particularly clinical outcomes.

  7. 基于TeamCenter平台的TBOM研究%Test-BOM Technology Based on Platform of TeamCenter

    Institute of Scientific and Technical Information of China (English)

    赵晓莉

    2014-01-01

    Product Data Management system organizes and manages product data which include informa-tion of product structure on the basis of bill of materials (BOM) in stages of design, process and manufac-ture, generating design-BOM, process-BOM and manufacture-BOM etc. The framework of BOM was adopt-ed to organize test data to build data management of product lifecycle from design,process,manufacture to test. The evolution of test-BOM was presented from design-BOM to neutral-BOM, and then to test-BOM. It will meet requirements of test data management in different enterprise to build test-BOM.%产品数据管理(PDM)系统通过包含产品结构信息的物料清单(BOM),来进行设计、工艺、制造等环节数据的组织和管理,由此产生了设计BOM(EBOM)、工艺BOM(PBOM)和制造BOM(MBOM)等。若产品试验过程数据按BOM来组织和管理,则可与设计、工艺、制造等环节关联,构建产品全生命周期数据管理。就试验BOM(TBOM)进行了深入研究,即从EBOM入手,依靠中性BOM(NBOM),最终演变成TBOM。通过对TBOM的维护,可满足不同企业对试验数据管理的需求。

  8. Development of nuclear fuel cycle technologies - bases of long-term provision of fuel and environmental safety of nuclear power

    Energy Technology Data Exchange (ETDEWEB)

    Solonin, M.I.; Polyakov, A.S.; Zakharkin, B.S.; Smelov, V.S.; Nenarokomov, E.A.; Mukhin, I.V. [SSC, RF, A.A. Bochvar ALL-Russia Research Institute of Inorganic Materials, Moscow (Russian Federation)

    2000-07-01

    To-day nuclear power is one of the options, however, to-morrow it may become the main source of the energy, thus, providing for the stable economic development for the long time to come. The availability of the large-scale nuclear power in the foreseeable future is governed by not only the safe operation of nuclear power plants (NPP) but also by the environmentally safe management of spent nuclear fuel, radioactive waste conditioning and long-term storage. More emphasis is to be placed to the closing of the fuel cycle in view of substantial quantities of spent nuclear fuel arisings. The once-through fuel cycle that is cost effective at the moment cannot be considered to be environmentally safe even for the middle term since the substantial build-up of spent nuclear fuel containing thousands of tons Pu will require the resolution of the safe management problem in the nearest future and is absolutely unjustified in terms of moral ethics as a transfer of the responsibility to future generations. The minimization of radioactive waste arisings and its radioactivity is only feasible with the closed fuel cycle put into practice and some actinides and long-lived fission radionuclides burnt out. The key issues in providing the environmentally safe fuel cycle are efficient processes of producing fuel for NPP, radionuclide after-burning included, a long-term spent nuclear fuel storage and reprocessing as well as radioactive waste management. The paper deals with the problems inherent in producing fuel for NPP with a view for the closed fuel cycle. Also discussed are options of the fuel cycle, its effectiveness and environmental safety with improvements in technologies of spent nuclear fuel reprocessing and long-lived radionuclide partitioning. (authors)

  9. Feed tank transfer requirements

    Energy Technology Data Exchange (ETDEWEB)

    Freeman-Pollard, J.R.

    1998-09-16

    This document presents a definition of tank turnover; DOE responsibilities; TWRS DST permitting requirements; TWRS Authorization Basis (AB) requirements; TWRS AP Tank Farm operational requirements; unreviewed safety question (USQ) requirements; records and reporting requirements, and documentation which will require revision in support of transferring a DST in AP Tank Farm to a privatization contractor for use during Phase 1B.

  10. 3D打印技术在翡翠雕刻的应用%The jade carving technology based on 3D printing

    Institute of Scientific and Technical Information of China (English)

    程远

    2015-01-01

    This study will focus on the current trends in the development of the jade carving technology based on 3D printin gand study through the oreti-Cal and practical opplication of 3D printing based on product design for a number of Powerful arguments on a feasibility analysis of the future development of the jade carving technology,and a wide variety of development ideas.%本文是针对当前3D打印技术应用在翡翠雕刻领域做出的一个探讨和研究,通过对于3D打印技术在产品设计应用过程中的一些有力的论据,阐述了其在翡翠雕刻领域的可行性分析,并提出了多元化的发展思路。

  11. Implementation of 7e learning cycle model using technology based constructivist teaching (TBCT) approach to improve students' understanding achievment in mechanical wave material

    Science.gov (United States)

    Warliani, Resti; Muslim, Setiawan, Wawan

    2017-05-01

    This study aims to determine the increase in the understanding achievement in senior high school students through the Learning Cycle 7E with technology based constructivist teaching approach (TBCT). This study uses a pretest-posttest control group design. The participants were 67 high school students of eleventh grade in Garut city with two class in control and experiment class. Experiment class applying the Learning Cycle 7E through TBCT approach and control class applying the 7E Learning Cycle through Constructivist Teaching approach (CT). Data collection tools from mechanical wave concept test with totally 22 questions with reability coefficient was found 0,86. The findings show the increase of the understanding achievement of the experiment class is in the amount of 0.51 was higher than the control class that is in the amount of 0.33.

  12. Image Hiding Technology Based on DCT and Chaos%基于DCT和混沌的图像隐藏技术①

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

      提出一种基于 DCT 和混沌的图像隐藏算法。首先利用混沌系统产生混沌序列对秘密图像进行加密,然后利用DCT变换与混沌序列把秘密图像隐藏到载体图像中。实验结果表明,该算法具有良好的安全性和隐藏效果。%An improved image hiding technology based on DCT and chaos is presented. We use chaotic system to generate one chaotic sequence which is utilized to encrypt the secret image, and then we use DCT and chaotic sequence to realize the secret image hiding in the host image. Simulation results show that the algorithm has good security and hiding effect.

  13. A preliminary study of achievement, attitudes toward success in mathematics, and mathematics anxiety with technology-based instruction in brief calculus.

    Science.gov (United States)

    Alkhateeb, Haitham M

    2002-02-01

    This study was designed to compare achievement, attitudes toward success in mathematics, and mathematics anxiety of college students taught brief calculus using a graphic calculator, with the achievement and attitudes and anxiety of students taught using the computer algebra system Maple, using a technology based text book. 50 men and 50 women, students in three classes at a large public university in the southwestern United States, participated. Students' achievement in brief calculus was measured by performance on a teacher-made achievement test given at the end of the study. Analysis of variance showed no significant difference in achievement between the groups. To measure change in attitudes and anxiety, responses to paper-and-pencil inventories indicated significant differences in favor of students using the computer.

  14. Manufacturing a Porous Structure According to the Process Parameters of Functional 3D Porous Polymer Printing Technology Based on a Chemical Blowing Agent

    Science.gov (United States)

    Yoo, C. J.; Shin, B. S.; Kang, B. S.; Yun, D. H.; You, D. B.; Hong, S. M.

    2017-09-01

    In this paper, we propose a new porous polymer printing technology based on CBA(chemical blowing agent), and describe the optimization process according to the process parameters. By mixing polypropylene (PP) and CBA, a hybrid CBA filament was manufactured; the diameter of the filament ranged between 1.60 mm and 1.75 mm. A porous polymer structure was manufactured based on the traditional fused deposition modelling (FDM) method. The process parameters of the three-dimensional (3D) porous polymer printing (PPP) process included nozzle temperature, printing speed, and CBA density. Porosity increase with an increase in nozzle temperature and CBA density. On the contrary, porosity increase with a decrease in the printing speed. For porous structures, it has excellent mechanical properties. We manufactured a simple shape in 3D using 3D PPP technology. In the future, we will study the excellent mechanical properties of 3D PPP technology and apply them to various safety fields.

  15. The Research on Definition and Classification Standard of Technology-Based Small and Medium Enterprises in China%我国科技型中小企业定义及划型标准的研究

    Institute of Scientific and Technical Information of China (English)

    陈志军; 温洲; 李享

    2016-01-01

    Through analyzing and comparing the classification standards of technology-based companies, hi-tech companies, and small and medium enterprises, this paper proposes the definition of technology-based small and medium enterprises (hereinafter shortened as SMEs). Three key factors of the technology-based SMEs are identified and examined: the personnel engaged in science and technology activities, input into science and technology activities and the science and technology output. Finally, the paper goes on to propose the classification standards of technology-based SMEs in China, based on the threshold evaluation methodology. Furthermore, the classification standards of technology-based SMEs are differentiated between national level and provincial level, according to actual conditions respectively.%本文通过对科技型企业、高新技术企业和中小企业的界定指标进行研究分析,提出科技型中小企业的定义,重点分析了科技型中小企业的三大核心要素(科技人员、科技投入和科技产出)。在此基础上,研究提出基于划线评价法的我国科技型中小企业划型标准,并明确细分为国家级和省级科技型中小企业划型标准。

  16. 基于电液比例控制的液压支架搬运技术研究%Research on hydraulic support handling technology based on electro-hydraulic proportional control system

    Institute of Scientific and Technical Information of China (English)

    周国力; 杨国宏

    2016-01-01

    Abstr act: According to the requirements of the working face of the coal mine hydraulic support installation and dismantle mechanization process, a novel kind of hydraulic support handling technology based on electro-hydraulic proportional control system is proposed. The hydrau lic drive system with proportional control technology uses the closed volume control circuit system of the electro-hydraulic proportional variable displacement pump control motor as the driving scheme of the hydraulic support transportation vehicle system. The Matlab software is used for the system simulation. In order to improve the stability and fast performance of the system, a genetic algorithm based PID correction control is presented and the simulation results show that the system has good stability and better control performance after correction.%根据煤矿井下工作面液压支架安装搬运的技术要求,提出了一种采用电液比例技术驱动控制的液压支架搬运系统。该系统采用电液控制技术,采用电液比例变量泵控马达闭式容积调速回路系统作为液压支架搬运系统的动力驱动方案。运用Matlab软件对系统进行了仿真。为了进一步改善系统的稳定性和快速性,提出了基于遗传算法的PID校正控制方案。仿真结果表明,校正后的系统具有较好的稳定性和控制效果。

  17. 二维码防伪技术在可变数据印刷中的应用%Application of Anti-counterfeiting Technology Based on Two-dimensional Bar Code in Variable Data Printing

    Institute of Scientific and Technical Information of China (English)

    肖菲菲; 刘真

    2011-01-01

    The principle of two-dimensional bar code anti-counterfeiting technology was analyzed.A plan of applying two-dimensional code anti-counterfeiting technology in variable-data printing was put forward.On the basis of experiments on generation and recognition of two-dimensional bar code,anti-counterfeiting properties of two different two-dimensional bar codes(PDF417 code and QR code) were obtained and their difference was compared.The theoretical analysis and experiment results showed that anti-counterfeiting technology based on two-dimensional bar code can be used in variable data printing,besides,different two-dimensional bar codes have different anti-counterfeiting properties;different two-dimensional bar code should be selected according to specific requirements.%分析了二维码的防伪原理,提出了在可变数据印刷中应用二维码进行防伪的方案,在完成基于可变数据印刷的二维码的生成和识别实验的基础上,设计实验比较得出了不同二维码(PDF417码与QR码)的防伪特性的差异。理论分析及实验结果表明,利用二维码对可变数据印刷进行防伪的方案是可行的,并且不同二维码的防伪特性存在差异,在实际应用中可以根据具体的要求选用不同的二维码。

  18. 纳米材料绿色制版技术的版材研究%Research on the Printing Plate of Green Plate Making Technology Based on Nano-Materials

    Institute of Scientific and Technical Information of China (English)

    周海华; 刘云霞; 宋延林

    2012-01-01

    Plate making is one of the key technologies in printing industry. So far there are mainly two technologies for plate making include laser phototypesetting technology and computer to plate technology. These technologies are based on photosensitive imaging principle, and need chemical treatment processes such as development, fixing etc. Green plate making technology based on nano-materials has many advantages such as pollution free and low cost, as it abandons the i- dea of sensitization imaging. The special nano and micro-structure of the plate will greatly influence the quality of printing products. In this paper, the research on the print plate is briefly introduced. Through optimizing the preparation process of the printing plate, the resolution and printability are greatly improved.%制版技术是印刷产业的关键技术之一。目前的印刷制版技术主要有激光照排制版技术和计算机直接制版技术。这两项制版技术是基于感光成像原理,需要显影、冲洗等化学处理过程。基于纳米材料的绿色制版技术无需感光成像,省略了显影、冲洗等化学处理过程,是一项环境友好、低成本的制版技术。其中,版材的纳微米结构对印刷质量有重要影响。简要介绍具有纳微米结构的版材的制备过程,通过优化版基制备条件,可以有效提高印版的分辨率和印刷适应性。

  19. 导管室护士的素质要求及护理体会%Quality Requirements and Nursing Experience of Catheter Room Nurses

    Institute of Scientific and Technical Information of China (English)

    张丽珈

    2015-01-01

    随着21世纪老龄化社会的到来,心血管病已成为威胁人类生命的头号杀手,以心导管为基础的介入性诊疗技术逐渐成为临床诊治心血管疾病的有效方法。心血管介入诊疗工作离不开相应的护理技术的发展,而心导管室护理则是从心血管病护理中演变出来的一门全新的技术。本文从医疗角度阐明导管室护士的素质要求与护理配合。%With aging society coming in 21st century, cardiovascular disease had been the leading murder of human life threat, at present, interventional diagnosis and treatment technology, based on the cardiac catheterization, was getting the most effective methods of clinical diagnosis and treatment of cardiovascular diseases. Cardiovascular interventional diagnosis and treatment work was closely related to the corresponding nursing technology development, and, conduit room nursing was a kind of whole new cardiovascular nursing plan. For that, in this paper, it will be discussed that conduit room nursing workers’ quality requirement and nursing experience.

  20. Feed tank transfer requirements

    Energy Technology Data Exchange (ETDEWEB)

    Freeman-Pollard, J.R.

    1998-09-16

    This document presents a definition of tank turnover. Also, DOE and PC responsibilities; TWRS DST permitting requirements; TWRS Authorization Basis (AB) requirements; TWRS AP Tank Farm operational requirements; unreviewed safety question (USQ) requirements are presented for two cases (i.e., tank modifications occurring before tank turnover and tank modification occurring after tank turnover). Finally, records and reporting requirements, and documentation which will require revision in support of transferring a DST in AP Tank Farm to a privatization contractor are presented.

  1. Micro technology based sun sensor

    DEFF Research Database (Denmark)

    Hales, Jan Harry; Pedersen, Martin; Fléron, René

    2003-01-01

    There is increasing interest among universities in the scientific and educational possibilities of picosatellites base on the CubeSat 5 concept. Due to sever mass and dimension constraints place on this type of satellites, new approaches and ideas regarding different systems arises to accommodate...... DTUsat sun sensors are needed along with a magnetometer to obtain unambiguous attitude determination for the ACDS and the payloads - an electrodynamic tether and a camera. The accuracy needed was not obtainable by employing conventional attitude sensors. Hence a linear slit sensor was designed...

  2. Discovering system requirements

    Energy Technology Data Exchange (ETDEWEB)

    Bahill, A.T.; Bentz, B. [Univ. of Arizona, Tucson, AZ (United States). Systems and Industrial Engineering; Dean, F.F. [Sandia National Labs., Albuquerque, NM (United States)

    1996-07-01

    Cost and schedule overruns are often caused by poor requirements that are produced by people who do not understand the requirements process. This report provides a high-level overview of the system requirements process, explaining types, sources, and characteristics of good requirements. System requirements, however, are seldom stated by the customer. Therefore, this report shows ways to help you work with your customer to discover the system requirements. It also explains terminology commonly used in the requirements development field, such as verification, validation, technical performance measures, and the various design reviews.

  3. Ontology Requirements Specification

    OpenAIRE

    Suárez-Figueroa, Mari Carmen; Gómez-Pérez, A.

    2012-01-01

    The goal of the ontology requirements specification activity is to state why the ontology is being built, what its intended uses are, who the end users are, and which requirements the ontology should fulfill. This chapter presents detailed methodological guidelines for specifying ontology requirements efficiently. These guidelines will help ontology engineers to capture ontology requirements and produce the ontology requirements specification document (ORSD). The ORSD will play a key role dur...

  4. 基于决策树的IDS报警数据融合技术研究%RESEARCH ON IDS SECURITY DATA FUSION TECHNOLOGY BASED ON DECISION TREE

    Institute of Scientific and Technical Information of China (English)

    黄正兴; 苏旸

    2013-01-01

    针对当前多个IDS的相互协作带来的海量报警数据,提出一种基于决策树的IDS报警数据融合技术,介绍决策树及其构造算法ID3,并利用决策树改进IDS报警数据融合中的属性匹配融合技术,提高了融合效率,融合后的报警数据降低了漏警率。实验证明了该方法的有效性。%In order to reduce the amount of security data produced by the collaboration of a lot of intrusion detection systems , the paper puts forward an IDS security data fusion technology based on decision tree and introduces both itself and its building arithmetic called ID 3. Then it adopts decision tree to ameliorate the attribute matching fusion technology in IDS security data fusion ,so that its fusion efficiency is in-creased and its missing rate of fused security data is decreased .Experiment confirms the validity of the method .

  5. Development and evaluation of an up-converting phosphor technology-based lateral flow assay for rapid and quantitative detection of aflatoxin B1 in crops.

    Science.gov (United States)

    Zhao, Yong; Liu, Xiao; Wang, Xiaochen; Sun, Chongyun; Wang, Xinrui; Zhang, Pingping; Qiu, Jingfu; Yang, Ruifu; Zhou, Lei

    2016-12-01

    Contamination of grains and other crops by aflatoxin B1 (AFB1), a highly toxic aflatoxin produced by Aspergillus flavus and Aspergillus parasiticus, poses a serious threat to human health and is an important food safety issue. In this study, a competitive up-converting phosphor technology-based lateral flow (AFB1-UPT-LF) assay was developed for rapid detection of AFB1. Detection sensitivity of the proposed assay can reach 0.03ngmL(-1) for standard AFB1 solutions, with the coefficients of variation (CV) less than 10% (from 1.0 to 9.4%). A good linearity (r=0.9889) was observed for quantification of AFB1 from 0.03 to 1000ngmL(-1). Except for aflatoxin M1, no cross-reactivity was found with the abrin, ricin, ochratoxin A, botulinum toxin, shiga toxin 1, shiga toxin 2, and staphylococcal enterotoxin B, even at high concentrations of 100 or 1000ngmL(-)(1). After optimizing the extraction of AFB1, the assay showed good tolerance to various crop samples, with the detection limit (from 0.1 to 5ngg(-)(1)) lower than the corresponding maximum residue level (MRL) set in China. The AFB1-UPT-LF assay provides a promising tool for rapid on-site detection of AFB1 because of its high sensitivity, specificity, and sample tolerance. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. 基于互联与认证的无线路由器关键技术%Wireless router technologies based on interconnection and certification

    Institute of Scientific and Technical Information of China (English)

    朱云雷

    2014-01-01

    针对当前移动互联网设备对低成本、全覆盖和实时访问 Internet 的要求,分析当前无线接入网技术的优缺点,提出了采用用户自主构建基于互联与认证的 WLAN 的技术方案和关键技术,可以满足智能移动终端的快速发展及对联网的需要,同时可以避免无线热点重复建设和保证用户富裕带宽的收益性,降低网络运营成本,实现资源有效利用。%With the low-cost, full coverage and real-time Internet access demands of the current mobile devices and the analysis of the current strengths and weaknesses of the radio access network technology, this paper proposes a technical solution and the key technology based on interconnection and certified wireless router which can avoid waste of resources, reduce network operating costs and achieve efficiency by selling excess bandwidth.

  7. Analysis of WebRTC Technology Based on HTML5%基于HTML5的WebRTC技术浅析

    Institute of Scientific and Technical Information of China (English)

    梁艳

    2014-01-01

    With the rapid development of mobile internet and large popularity of intel igent terminals, WebRTC technology based on HTML5 becomes the trend of mobile internet multimedia real-time communications. This paper analyzes WebRTC architecture, key technologies, standards, and its characteristics, researches a series of application scenarios and modes, and discusses the application of WebRTC combination of IMS.%随着移动互联网的快速发展和智能终端的迅速普及,基于HTML5的WebRTC技术成为移动互联网多媒体实时通信的发展趋势。文章从WebRTC总体架构、关键技术、标准情况及其特性等方面进行分析和探讨,研究WebRTC的一系列应用场景和应用模式,并对WebRTC与IMS的结合应用进行了讨论。

  8. Anti-malicious Code Technology Based on SSDT Restoration%基于SSDT恢复的反恶意代码技术

    Institute of Scientific and Technical Information of China (English)

    陈萌

    2009-01-01

    通过修改系统服务调度表(SSDT),恶意代码可以避免被杀毒软件或反恶意软件清除.针对SSDT挂钩技术,通过系统文件霞定位,实现基于SSDT恢复的反恶意代码技术,阐述Ntoskrnl.exe文件的重装方法和Nmskrnl.exe文件偏移比较法.实验结果证明,该技术能使恶意代码和木马程序失效,保障系统安全.%By amending System Service Dispatch Table(SSDT), the malicious code can avoid being cleared by antivirus software or anti-malice software. Aiming at SDDT hook technology, this paper realizes an anti-malicious code technology based on SSDT restoration through system file relocation. It expatiates the method of resetting Ntoskrnl.exe files and the method of shifting comparison of Ntoskml.exe files. Experimental results show that this technology can invalidate malicious codes and Trojan programs and guarantee system security.

  9. 基于图文法制导的ER图自动绘制技术%ER-Diagram Automatic Drawing Technology Based on GraphGrammars-Directed

    Institute of Scientific and Technical Information of China (English)

    赵凤芝; 侯柏苓; 文必龙

    2012-01-01

    逻辑模型可视化对于软件开发和技术研究具有重要的意义.提出了一种基于图文法制导ER图自动绘制技术,并对图文法进行扩展命名为ER图文法,它克服了在原有建模工具中绘制ER图图幅数量有限和不易更改的缺点,并从语义上对实体关系及ER图绘制规则进行描述,提出ER图自动布局和布线算法,实现ER图的自动绘制.%To software development and technology research, logical model visualization has an important significance. This paper puts forward an ER-diagram automatic drawing technology based on graph grammar-directed, and expands graph grammar named ER graph grammar. It overcomes the shortcoming of limited map number for drawing ER-diagram and difficult changing in original modeling tools, and describes relationship of entities and drawing rules of ER-diagram on the semantic. ER-diagram automatic placement and automatic wiring are presented, and ER-diagram automatic drawing is realized.

  10. Rapid multiplex detection of 10 foodborne pathogens with an up-converting phosphor technology-based 10-channel lateral flow assay.

    Science.gov (United States)

    Zhao, Yong; Wang, Haoran; Zhang, Pingping; Sun, Chongyun; Wang, Xiaochen; Wang, Xinrui; Yang, Ruifu; Wang, Chengbin; Zhou, Lei

    2016-02-17

    The rapid high-throughput detection of foodborne pathogens is essential in controlling food safety. In this study, a 10-channel up-converting phosphor technology-based lateral flow (TC-UPT-LF) assay was established for the rapid and simultaneous detection of 10 epidemic foodborne pathogens. Ten different single-target UPT-LF strips were developed and integrated into one TC-UPT-LF disc with optimization. Without enrichment the TC-UPT-LF assay had a detection sensitivity of 10(4) CFU mL(-1) or 10(5) CFU mL(-1) for each pathogen, and after sample enrichment it was 10 CFU/0.6 mg. The assay also showed good linearity, allowing quantitative detection, with a linear fitting coefficient of determination (R(2)) of 0.916-0.998. The 10 detection channels did not cross-react, so multiple targets could be specifically detected. When 279 real food samples were tested, the assay was highly consistent (100%) with culture-based methods. The results for 110 food samples artificially contaminated with single or multiple targets showed a high detection rate (≥ 80%) for most target bacteria. Overall, the TC-UPT-LF assay allows the rapid, quantitative, and simultaneous detection of 10 kinds of foodborne pathogens within 20 min, and is especially suitable for the rapid detection and surveillance of foodborne pathogens in food and water.

  11. Research on Direct Broadcast Technology Based on Http Live Streaming%基于Http Live Streaming的直播技术研究

    Institute of Scientific and Technical Information of China (English)

    丁耀

    2014-01-01

    The paper makes an introduction of the streaming media technology based on Http Live Streaming, including system architecture, file format, data structure and streaming-media segment tools supplied by Apple Company. Proposes two kinds of audio and video acquisition program according to different application scene, designs and builds a direct broadcast system that based on Http Live Streaming. At the end does analysis on the characteristic of Http Live Streaming based system and the system optimization direction.%本文介绍了基于Http Live Streaming的流媒体技术,包括系统架构、文件格式、数据结构和苹果提供的流媒体分割工具。结合应用场合提出了两种音视频采集方案,设计并搭建了一套基于Http Live Streaming的直播系统。分析了基于Http Live Streaming的直播系统的特点以及系统优化方向。

  12. Paving the Way to Successful Implementation: Identifying Key Barriers to Use of Technology-Based Therapeutic Tools for Behavioral Health Care.

    Science.gov (United States)

    Ramsey, Alex; Lord, Sarah; Torrey, John; Marsch, Lisa; Lardiere, Michael

    2016-01-01

    This study aimed to identify barriers to use of technology for behavioral health care from the perspective of care decision makers at community behavioral health organizations. As part of a larger survey of technology readiness, 260 care decision makers completed an open-ended question about perceived barriers to use of technology. Using the Consolidated Framework for Implementation Research (CFIR), qualitative analyses yielded barrier themes related to characteristics of technology (e.g., cost and privacy), potential end users (e.g., technology literacy and attitudes about technology), organization structure and climate (e.g., budget and infrastructure), and factors external to organizations (e.g., broadband accessibility and reimbursement policies). Number of reported barriers was higher among respondents representing agencies with lower annual budgets and smaller client bases relative to higher budget, larger clientele organizations. Individual barriers were differentially associated with budget, size of client base, and geographic location. Results are discussed in light of implementation science frameworks and proactive strategies to address perceived obstacles to adoption and use of technology-based behavioral health tools.

  13. The Development of a Technology-Based Hierarchy to Assess Chronic Low Back Pain and Pain-Related Anxiety From a Fear-Avoidance Model.

    Science.gov (United States)

    Springer, Kristen S; George, Steven Z; Robinson, Michael E

    2016-08-01

    Previous studies have not examined the assessment of chronic low back pain (CLBP) and pain-related anxiety from a fear avoidance model through the use of motion-capture software and virtual human technologies. The aim of this study was to develop and assess the psychometric properties of an interactive, technologically based hierarchy that can be used to assess patients with pain and pain-related anxiety. We enrolled 30 licensed physical therapists and 30 participants with CLBP. Participants rated 21 video clips of a 3-D animated character (avatar) engaging in activities that are typically feared by patients with CLBP. The results of the study indicate that physical therapists found the virtual hierarchy clips acceptable and depicted realistic patient experiences. Most participants with CLBP reported at least 1 video clip as being sufficiently anxiety-provoking for use clinically. Therefore, this study suggests a hierarchy of fears can be created out of 21 virtual patient video clips paving the way for future clinical use in patients with CLBP. This report describes the development of a computer-based virtual patient system for the assessment of back pain-related fear and anxiety. Results show that people with back pain as well as physical therapists found the avatar to be realistic, and the depictions of behavior anxiety- and fear-provoking. Copyright © 2016 American Pain Society. Published by Elsevier Inc. All rights reserved.

  14. Technology-based Intervention Programs to Promote Stimulation Control and Communication in Post-coma Persons with Different Levels of Disability

    Directory of Open Access Journals (Sweden)

    Giulio E. Lancioni

    2014-02-01

    Full Text Available Post-coma persons in a minimally conscious state and with extensive motor impairment or emerging/emerged from such a state, but affected by lack of speech and motor impairment, tend to be passive and isolated. A way to help them develop functional responding to control environmental events and communication involves the use of intervention programs relying on assistive technology. This paper provides an overview of technology-based intervention programs for enabling the participants to (a access brief periods of stimulation through one or two microswitches, (b pursue stimulation and social contact through the combination of a microswitch and a sensor connected to a speech generating device (SGD or through two SGD-related sensors, (c control stimulation options through computer or radio systems and a microswitch, (d communicate through modified messaging or telephone systems operated via microswitch, and (e control combinations of leisure and communication options through computer systems operated via microswitch. Twenty-six studies, involving a total of 52 participants, were included in this paper. The intervention programs were carried out using single-subject methodology, and their outcomes were generally considered positive from the standpoint of the participants and their context. Practical implications of the programs are discussed.

  15. Assessing Requirements Quality through Requirements Coverage

    Science.gov (United States)

    Rajan, Ajitha; Heimdahl, Mats; Woodham, Kurt

    2008-01-01

    In model-based development, the development effort is centered around a formal description of the proposed software system the model. This model is derived from some high-level requirements describing the expected behavior of the software. For validation and verification purposes, this model can then be subjected to various types of analysis, for example, completeness and consistency analysis [6], model checking [3], theorem proving [1], and test-case generation [4, 7]. This development paradigm is making rapid inroads in certain industries, e.g., automotive, avionics, space applications, and medical technology. This shift towards model-based development naturally leads to changes in the verification and validation (V&V) process. The model validation problem determining that the model accurately captures the customer's high-level requirements has received little attention and the sufficiency of the validation activities has been largely determined through ad-hoc methods. Since the model serves as the central artifact, its correctness with respect to the users needs is absolutely crucial. In our investigation, we attempt to answer the following two questions with respect to validation (1) Are the requirements sufficiently defined for the system? and (2) How well does the model implement the behaviors specified by the requirements? The second question can be addressed using formal verification. Nevertheless, the size and complexity of many industrial systems make formal verification infeasible even if we have a formal model and formalized requirements. Thus, presently, there is no objective way of answering these two questions. To this end, we propose an approach based on testing that, when given a set of formal requirements, explores the relationship between requirements-based structural test-adequacy coverage and model-based structural test-adequacy coverage. The proposed technique uses requirements coverage metrics defined in [9] on formal high-level software

  16. Analysis of the Complex Characteristics of the Organization of Science and Technology-based Small-Micro Enterprises%科技型小微企业组织复杂性特征探析

    Institute of Scientific and Technical Information of China (English)

    刘利; 袁页

    2013-01-01

    According to the principles of complexity science theory and the reality of technology based small micro enterprises,the articles made a wide research on the small micro enterprise organization complexity at home,and focus on the characteristics of technological small micro enterprise environment complexity,the complexity of technology based smallmicro enterprise organization structure characteristics,the complexity characteristics of technology based small micro enterprise organization form.Also,the complexity of technology-based small micro enterprise organization management mode characteristics,small-micro enterprises exploration and the characteristics of the complexity of the organization's strategy are studied.%根据复杂性理论和小微企业的现实情况,在国内科技型小微企业研究综述的基础上,对科技型小微企业组织环境复杂性特征、科技型小微企业组织结构复杂性特征、科技型小微企业组织形态复杂性特征、科技型小微企业组织管理方式复杂性特征、科技型小微企业组织战略复杂性特征进行了探索和分析.

  17. Postmarket Requirements and Commitments

    Data.gov (United States)

    U.S. Department of Health & Human Services — Provides information to the public on postmarket requirements and commitments. The phrase postmarket requirements and commitments refers to studies and clinical...

  18. Requirements for existing buildings

    DEFF Research Database (Denmark)

    Thomsen, Kirsten Engelund; Wittchen, Kim Bjarne

    2012-01-01

    This report collects energy performance requirements for existing buildings in European member states by June 2012.......This report collects energy performance requirements for existing buildings in European member states by June 2012....

  19. Replacing reserve requirements

    OpenAIRE

    Edward J. Stevens

    1993-01-01

    An examination of the fading significance of the Federal Reserve System's reserve requirements and the recent flowering of required clearing balances, a rapidly growing feature of Reserve Bank operations.

  20. Requirements for existing buildings

    DEFF Research Database (Denmark)

    Thomsen, Kirsten Engelund; Wittchen, Kim Bjarne

    2012-01-01

    This report collects energy performance requirements for existing buildings in European member states by June 2012.......This report collects energy performance requirements for existing buildings in European member states by June 2012....

  1. Replacing reserve requirements

    OpenAIRE

    Edward J. Stevens

    1993-01-01

    An examination of the fading significance of the Federal Reserve System's reserve requirements and the recent flowering of required clearing balances, a rapidly growing feature of Reserve Bank operations.

  2. 40 CFR 141.80 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... exceeding the lead or copper action level shall implement all applicable source water treatment requirements...) NATIONAL PRIMARY DRINKING WATER REGULATIONS Control of Lead and Copper § 141.80 General requirements. (a... drinking water regulations for lead and copper. Unless otherwise indicated, each of the provisions of...

  3. 40 CFR 256.50 - Requirements.

    Science.gov (United States)

    2010-07-01

    ... Requirements. Section 4003(1) requires the State solid waste managment plan to idenifty means for coordinating... supply, waste water treatment, pesticides, ocean protection, toxic substances control, noise control, and..., including Soil Conservation Service (land spreading solid waste on food chain croplands); (5)...

  4. Future Home Network Requirements

    DEFF Research Database (Denmark)

    Charbonnier, Benoit; Wessing, Henrik; Lannoo, Bart;

    This paper presents the requirements for future Home Area Networks (HAN). Firstly, we discuss the applications and services as well as their requirements. Then, usage scenarios are devised to establish a first specification for the HAN. The main requirements are an increased bandwidth (towards 1...

  5. Future Home Network Requirements

    DEFF Research Database (Denmark)

    Charbonnier, Benoit; Wessing, Henrik; Lannoo, Bart

    This paper presents the requirements for future Home Area Networks (HAN). Firstly, we discuss the applications and services as well as their requirements. Then, usage scenarios are devised to establish a first specification for the HAN. The main requirements are an increased bandwidth (towards 1...

  6. PIT Coating Requirements Analysis

    Energy Technology Data Exchange (ETDEWEB)

    MINTEER, D.J.

    2000-10-20

    This study identifies the applicable requirements for procurement and installation of a coating intended for tank farm valve and pump pit interior surfaces. These requirements are intended to be incorporated into project specification documents and design media. This study also evaluates previously recommended coatings and identifies requirement-compliant coating products.

  7. Research of Dynamic Binding Modeling TechnologyBased on WEB Workflow%基于WEB工作流的动态绑定建模技术研究

    Institute of Scientific and Technical Information of China (English)

    江进

    2014-01-01

    工作流技术是实现业务流程建模、仿真、优化、集成的有效手段之一。尤其是基于WEB的工作流动态建模技术,是增强信息系统业务流程互联互通、实现业务流程动态可配置、流程优化重组的有力措施。文章首先分析了工作流控制模型,然后构建了基于WEB的多流程工作流协同控制体系。采用基于XML的技术方案给出了流程初始化定义的配置框架,通过工作流引擎调用WEB服务描述语言WSDL,实现了面向web服务的多流程动态绑定。达到了实际业务流程逻辑与流程组织逻辑分离的目的。%Workflow technology is one of the business process modeling, simulation, optimization, integrated and effective means of achieving. Especially the dynamic workflow modeling technology based on WEB, is to enhance the information system business process interoperability, realize the effective measures of dynamic configurable business process, process reengineering. Thesis analyzes the workflow control model, and then build a WEB-based multi-process workflows cooperative control system. XML-based technology solutions gives the configuration framework defined initialization process, call the WEB Services Description Language WSDL through the workflow engine to achieve a dynamic and multi-process-oriented web service bindings. Achieve the purpose of the actual business process logic and process organization logical separation.

  8. Predistortion linearization technology based on under-sampling method%欠采样方法在预失真线性化技术中的应用

    Institute of Scientific and Technical Information of China (English)

    詹鹏; 秦开宇; 陈长伟; 蔡顺燕

    2011-01-01

    Bandwidth of the feedback signal from the output of the power amplifier is too wide,and it needs high sampling rate to sample the feedback signal.For this problem, this paper proposes a predistortion linearization technology based on the under-sampling method, allowing the system to sample the feedback signal at a lower sampling rate, which is no smaller than two times of the input signal's bandwidth.It has no affect to the identification of the power amplifier's nonlinearity,and can achieve the same linear performance compared with the over-sampling method.So the predistortion linearization system is easier to design and realize.Simulation results show the correctness and the satisfactory linearization performance of this method,the conclusion is significance to the engineering practical application.%针对经功放输出后反馈回的信号频谱带宽较宽,对采样率要求较高的问题,提出一种基于欠采样方法的预失真线性化技术,使系统最低能以两倍输入信号带宽的采样率采样反馈信号,但却不影响对功放非线性参数的识别.且能达到与过采样方式相同的线性化性能,降低了数字基带预失真系统设计和实现的难度.仿真结果表明该方法是可行的,且能达到满意的线性化效果,该结论在工程实际应用中具有重要意义.

  9. Research on Parallel Unstructured Mesh Generation Technology Based on GPU%基于GPU的并行非结构网格生成技术研究

    Institute of Scientific and Technical Information of China (English)

    齐龙; 肖素梅; 刘云楚; 廖玲玲; 蔡云龙

    2013-01-01

    In order to solve the problems of unstructured mesh generation technology in time and memory, the parallel generation method of unstructured grid is researched, and the GPU unstructured mesh generation technology based on the framework of CUDA is put forward. In CUDA programming framework, unstructured mesh generation technology is applied to GPU parallel environment, Combining the high-speed parallel GPU with parallel delaunay generation technology. Its performance is evaluated by the analysis of the speedup rate and efficiency. According to the experimental results, the suggested method is of high efficiency. Compared with traditional methods, it greatly reduces the time consumption in the same mesh quality.%为了解决非结构网格生成在时间和内存上的问题,研究了非结构网格的并行生成方法,提出了一种基于CUDA架构的GPU并行非结构网格生成技术.该技术结合了GPU的高速并行性和并行Delaunay网格生成技术的优点,在CUDA编程框架下,将非结构网格生成的技术应用到GPU并行环境中.通过分析此方法的加速比和效率,对其性能进行了评估.实验结果表明,所提出的方法具备有高效性,与传统方法相比,在保证网格质量的同时,大幅度减少了其时间消耗.

  10. 基于云技术的计算模式及其实现%CLOUD TECHNOLOGY-BASED COMPUTING MODEL AND ITS IMPLEMENTATION

    Institute of Scientific and Technical Information of China (English)

    蒋建军; 丁志锋

    2016-01-01

    针对传统计算模式下设备、操作系统、应用程序和用户数据紧耦合的问题,提出基于云技术的计算模式,实现这四个要素的“完全分”和“自由合”。作为云技术计算模式的原型实现,云平台在后端构建存储云、桌面云和应用云,将用户数据、操作系统和应用程序都集中部署在数据中心,可以让用户专注于自己的数据,在任何时候、从任何地方、使用任何设备、连接任何桌面、运行任何应用程序来访问、处理和分享自己的数据。%In light of the problem of tight coupling among device,operating system,application and data in traditional computing mode, we present the cloud technology-based computing mode to achieve the “complete separation”and “free combination”of these four elements. As the prototype implementation of cloud computing mode,the cloud platform constructs the storage could,desktop cloud and application cloud on backend,and centralises user data,operating system and applications in data centre,which is able make users focus on the data of their own,and access,process and share their data in any time,from anywhere,using any device,connecting any desktop and running any application.

  11. 内核入侵隐藏技术的研究与实现%Research and Realization of Concealment Technology Based on Kernel Hacking

    Institute of Scientific and Technical Information of China (English)

    李鹏; 王汝传

    2011-01-01

    Makes research on code concealment technology based on kernel hacking module without loadable kernel.It firstly analyzes the difference in kernel hacking method between module with loadable kernel and module without loadable kernel.Then.it expatiates the eight main steps of kernel hacking, which includes computing the address of system call table, calculating the address of kmalloc function, programming kernel space memory assignment function, implementing invasion codes, processing assembly code, extracting code segments and relocation information, assigning kernel space memory, and writing assigned memory.Based on summarizing the concealment technical principles of kernel hacking codes, finally designs and implements the kernel hacking technologies, which includes concealing file information, process information and network connections.%对不支持可加载模块的系统内核入侵代码隐藏技术进行了研究.比较了内核支持可加载模块和内核不支持可加载模块的内核入侵的方法区别,阐述了内核入侵在求解系统调用表的地址、kmalloc函数的地址、编写函数分配内核空间内存、编写入侵代码、汇编代码处理、提取代码段及重定位信息、分配内核空间的内存、代码写入分配的内存等八个主要流程.在总结入侵代码隐藏技术原理的基础上,给出了入侵代码隐藏文件信息、进程信息和网络连接技术的详细设计实现.

  12. 中国企业技术并购的经营业绩研究%Performance of Chinese firms to undertake technology - based acquisitions

    Institute of Scientific and Technical Information of China (English)

    孙忠娟; 谢伟

    2012-01-01

    The aim of this study is to test the performance of Chinese firms undertaking technology - based acquisitions. We examine the innovation performance' s change in Chinese firms after technology acquisition by two - sample Wilcoxon - test. Overall, this study found that : ( 1 ) the Mean value of economical benefits increase significantly after acquisition, (2) According to year - value, econom- ical benefits after acquisition is higher than the average value before acquisition, (3) Operation benefits is upgraded significantly in the first and the second year comparing to its last year, but there is no obvious variation yearly in net profit after acquisition. At last, some management enlightenments are put forward.%研究目标是分析中国企业作为技术并购企业的经营业绩。采用非参数双样本Wilcoxon显著性检验,验证了企业技术并购后经营业绩的变化情况。结果显示:(1)并购后,经营业绩均值显著提高;(2)并购后,经营业绩每一年年值都显著高于并购前;(3)并购后的第一和第二年营业收入逐年提升显著,净利润逐年提升不显著。最后,本文指出了结论的管理启示。

  13. Image authentication technology based on digital watermarking%基于数字水印的图像认证技术

    Institute of Scientific and Technical Information of China (English)

    刘挺

    2014-01-01

    在信息时代,计算机技术发展迅速,防伪技术跟随着科技也在进一步提高。在这个崭新的数字媒体世界里,我们通过数字媒体资源进行着快捷便利的信息交流。但是也为我们带来了安全隐患。这些数字信息很容易被修改,不管是不是恶意的修改,都会对人们的认知造成误导或者造成其他严重的后果。基于这种情况的出现,为保护数字媒体资源,数字水印技术和图像认证技术越来越被人们所关注。本文将对基于数字水印的图像认证技术进行简单的阐述。%In the information age,as the rapid development of computer technology,anti-counterfeiting technology are further improved with science and technology.In this new world of digital media,we exchange the information fastly and conveniently through the digital media resources.But also bring us the safe hidden trouble.The digital information is easy to modify,whether malicious changes or not,will mislead people's cognitive or other serious consequences.Based on this situation,for protecting the digital media resources,the digital watermark technology and image authentication technology is more and more attention by people.This article will describe the image authentication technology based on digital watermarking.

  14. 基于猴群算法的入侵检测技术%Intrusion Detection Technology Based on Monkey Algorithm

    Institute of Scientific and Technical Information of China (English)

    张佳佳; 张亚平; 孙济洲

    2011-01-01

    针对入侵检测系统存在高漏报率的问题,提出一种基于猴群算法的入侵检测技术.利用猴群算法从网络审计数据KDD99数据集中生成一个分类的规则集合,采用支持度-置信度模型实现猴群算法的目标函数,以控制生成规则的质量,将动态生成的规则应用于基于规则的的入侵检测系统中.实验结果表明,基于猴群算法的入侵检测技术可改进生成规则的质量,提高入侵检测系统的检测率.%For the current Intrusion Detection System(IDS) has high false negative rate, this paper presents an intrusion detection technology based on Monkey Algorithm(MA).It uses the MA to derive a set of classification rules from network data, KDD99 data set, and the support-confidence framework is utilized as fitness function to judge the quality of each rule.The generated rules are used to detect or classify network intrusions in a real-time environment.Experimental results show that the MA-based technology can improve the quality of generating rules, so that it can improve the performance of IDS.

  15. Research of Dot Detection Technology Based on Mobile Platform%基于移动平台的印刷网点检测技术

    Institute of Scientific and Technical Information of China (English)

    丁海洋; 姚佳楠; 王明飞

    2014-01-01

    为实现通用便携的印刷网点检测,提出基于移动平台的印刷网点检测技术。印刷网点检测,先进行图像分割,再获取网点中心,计算网线角度等。为在基于Android操作系统的智能平台上实现印刷网点检测,采用Android-JNI技术,该技术的核心是NDK编译,先配置NDK编译环境,再编辑C/C++源文件和mk文件,最后通过NDK编译,将C/C++编辑的图像处理程序编译为Android工程可以调用的库文件。实验验证,本系统可在运行Android系统的移动平台上实现网点图像的自动阈值分割。%In order to achieve portable detection device for print, this paper indicates a dot detection technology based on mobile platform. Dot detection includes image segmentation, obtaining center of dot, computing dot angle etc. In the mobile platform with Android OS, it is realizing dot detection by using android-JNI technology. The core of Android-JNI is NDK compiler which consists of 3 steps. It configures first the NDK compiler environment, and then edits the C/CPP source file and the mk file, finally, through the NDK compiler, converts the image processing program editing by C/C++language to the library file that Android project can call. Experimental results show that this system can realize the automatic threshold image segmentation in the mobile platform with Android OS.

  16. Transportation System Requirements Document

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    This Transportation System Requirements Document (Trans-SRD) describes the functions to be performed by and the technical requirements for the Transportation System to transport spent nuclear fuel (SNF) and high-level radioactive waste (HLW) from Purchaser and Producer sites to a Civilian Radioactive Waste Management System (CRWMS) site, and between CRWMS sites. The purpose of this document is to define the system-level requirements for Transportation consistent with the CRWMS Requirement Document (CRD). These requirements include design and operations requirements to the extent they impact on the development of the physical segments of Transportation. The document also presents an overall description of Transportation, its functions, its segments, and the requirements allocated to the segments and the system-level interfaces with Transportation. The interface identification and description are published in the CRWMS Interface Specification.

  17. Psychological Treatment

    Science.gov (United States)

    ... IBS Pain IBS Global Treatments IBS Diet Low FODMAP Diet Complimentary or Alt Treatments Medications Psychological Treatments ... IBS Pain IBS Global Treatments IBS Diet Low FODMAP Diet Complimentary or Alt Treatments Medications Psychological Treatments ...

  18. A Technology Based on Human Exoskeleton for Enhancing Locomotion Capability of Lower Extremity during Extravehicular Tasks%基于外骨骼技术的舱外作业下肢运动能力增强技术

    Institute of Scientific and Technical Information of China (English)

    张向刚; 秦开宇; 张羿; 石宇亮; 王浩

    2015-01-01

    In the future, the astronauts will have to do more complex extravehicular activity( EVA) tasks with more equipments and payloads in a variety of harsh environments for longer time.There-fore, the requirements on astronaut’ s locomotion capacity during EVA tasks will be higher.In this paper, a technology based on human exoskeleton was introduced to enhance the locomotion capacity of Lower Extremity.The astronaut’ s exoskeleton includes the bionic mechanical structure, actua-tors, energy system, sensing system and control system.The technical approaches mainly include:establishing the dynamic model of the astronaut ’ s exoskeleton system, perceiving the posture of limbs and movement intention, controlling the actuators to enhance the movement ability of the lower extremity.The validity of the astronaut’ s exoskeleton system was demonstrated by the ground experi-mental data and simulation.%针对未来航天活动中航天员面对的在复杂环境下携带大量载荷进行长时间、大范围舱外作业的需求对航天员舱外运动能力要求较高的背景,阐述了一种基于外骨骼技术的舱外作业下肢运动能力增强技术,介绍的外骨骼系统包括仿形机械结构分系统、执行机构分系统、能源分系统、感知分系统和控制分系统,还重点介绍了动力学分析与建模、运动状态和运动意图感知、实时控制等关键技术,并通过地面实验数据和仿真证明了这种方法的有效性。

  19. PARACOCCIDIOIDOMYCOSIS TREATMENT

    Directory of Open Access Journals (Sweden)

    Maria Aparecida SHIKANAI-YASUDA

    2015-09-01

    Full Text Available SUMMARYConsidered to be an emerging endemic mycosis in Latin America, paracoccidioidomycosis is characterized by a chronic course and involvement of multiple organs in immunocompromised hosts. Infection sequelae are mainly related to pulmonary and adrenal insufficiency. The host-parasite interaction results in different expressions of the immune response depending on parasite pathogenicity, fungal load and genetic characteristics of the host. A few controlled and case series reports have shown that azoles and fast-acting sulfa derivatives are useful treatment alternatives in milder forms of the disease. For moderate/severe cases, more prolonged treatments or even parenteral routes are required especially when there is involvement of the digestive tract mucosa, resulting in poor drug absorption. Although comparative studies have reported that shorter treatment regimens with itraconazole are able to induce cure in chronically-infected patients, there are still treatment challenges such as the need for more controlled studies involving acute cases, the search for new drugs and combinations, and the search for compounds capable of modulating the immune response in severe cases as well as the paradoxical reactions.

  20. Distribution of certain drug products by registered blood establishments and comprehensive hemophilia diagnostic treatment centers that qualify as health care entities; Prescription Drug Marketing Act of 1987; Prescription Drug Amendments of 1992; policies, requirements and administrative procedures. Final rule.

    Science.gov (United States)

    2008-10-09

    The Food and Drug Administration (FDA) is amending its regulations to allow certain registered blood establishments and comprehensive hemophilia diagnostic treatment centers that are also health care entities to distribute certain drug products. The final rule amends limited provisions of the regulations implementing the Prescription Drug Marketing Act of 1987 (PDMA), as modified by the Prescription Drug Amendments of 1992 (PDA). These regulations, among other things, restrict the sale, purchase, or trade of, or the offer to sell, purchase, or trade, prescription drugs purchased by hospitals and other health care entities.

  1. Avatar-assisted therapy: a proof-of-concept pilot study of a novel technology-based intervention to treat substance use disorders.

    Science.gov (United States)

    Gordon, Michael S; Carswell, Steven B; Schadegg, Mary; Mangen, Kayla; Merkel, Kelly; Tangires, Susan; Vocci, Frank J

    2017-09-01

    Avatar-assisted therapy (AAT) is a novel and emerging technology that uses the Internet to enable clinicians and clients in substance abuse treatment to participate in group counseling sessions from separate and remote locations in real time through the use of avatars and virtual environments. The current study is a pilot proof-of-concept feasibility study involving individuals in outpatient substance abuse treatment. This report addresses two questions: (1) are individuals who present for substance abuse treatment interested in receiving AAT and (2) what factors are associated with better treatment success. Individuals who presented at the treatment clinic who met study eligibility criteria, and provided their written informed consent to participate, were included in the current study (N = 59; 78% male). Twenty-eight (47.5%) participants completed 16 weeks of treatment and attended more sessions compared to non-completers (M = 14.3 vs. 7.5 p < .05). Those individuals who completed treatment were less likely to have a positive urine drug screen at baseline (21.5 vs. 78.6%; p < .05). Furthermore, those individuals who successfully completed treatment were less likely to have positive urine drug screens during treatment compared to those who did not complete (29.7% vs. 70.3%, p < .05). There were no arrests during treatment for completers and non-completers. Poor retention in substance use disorder treatment has long been a major problem for public health. AAT is a feasible approach that has the potential to expand treatment to individuals who might have difficulty accessing treatment. Moreover, AAT may be appealing to clients who are concerned about anonymity and confidentiality.

  2. Software Requirements Management

    Directory of Open Access Journals (Sweden)

    Ali Altalbe

    2015-04-01

    Full Text Available Requirements are defined as the desired set of characteristics of a product or a service. In the world of software development, it is estimated that more than half of the failures are attributed towards poor requirements management. This means that although the software functions correctly, it is not what the client requested. Modern software requirements management methodologies are available to reduce the occur-rence of such incidents. This paper performs a review on the available literature in the area while tabulating possible methods of managing requirements. It also highlights the benefits of following a proper guideline for the requirements management task. With the introduction of specific software tools for the requirements management task, better software products are now been developed with lesser resources.

  3. Turning Desirements into Requirements

    Science.gov (United States)

    2015-09-01

    budgets, assessment teams must wonder when to consider the cost of a particular solution. The DoD management systems wisely separate requirements gen...analysis so the The warfighter—the man or woman who goes into harm’s way— has every imperative to expect much of us as requirements managers, program...the man or woman who goes into harm’s way—has every imperative to expect much of us as requirements managers, program managers, and resource

  4. Anthropometric Requirements for Constellation

    Science.gov (United States)

    Raulu, Sudhakar; Margerum, Sarah; Dory, Jonathan; Rochlis, Jennifer

    2009-01-01

    This slide presentation reviews the requirement from an Anthropometric standpoint for the development of the Constellation's programs hardware, specifically the Orion crew exploration vehicle. The NASA JSC Anthropometry and Biomechanics Facility (ABF) provides anthropometry, strength, mobility, and mass properties requirements; gathers, interprets, manages and maintains the flight crew anthropometry database; and participates and provides input during crew selection. This is used to assist in requirements for vehicle and space suit design and for crew selection.

  5. Testing agile requirements models

    Institute of Scientific and Technical Information of China (English)

    BOTASCHANJAN Jewgenij; PISTER Markus; RUMPE Bernhard

    2004-01-01

    This paper discusses a model-based approach to validate software requirements in agile development processes by simulation and in particular automated testing. The use of models as central development artifact needs to be added to the portfolio of software engineering techniques, to further increase efficiency and flexibility of the development beginning already early in the requirements definition phase. Testing requirements are some of the most important techniques to give feedback and to increase the quality of the result. Therefore testing of artifacts should be introduced as early as possible, even in the requirements definition phase.

  6. Environmental Requirements Management

    Energy Technology Data Exchange (ETDEWEB)

    Cusack, Laura J.; Bramson, Jeffrey E.; Archuleta, Jose A.; Frey, Jeffrey A.

    2015-01-08

    CH2M HILL Plateau Remediation Company (CH2M HILL) is the U.S. Department of Energy (DOE) prime contractor responsible for the environmental cleanup of the Hanford Site Central Plateau. As part of this responsibility, the CH2M HILL is faced with the task of complying with thousands of environmental requirements which originate from over 200 federal, state, and local laws and regulations, DOE Orders, waste management and effluent discharge permits, Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) response and Resource Conservation and Recovery Act (RCRA) corrective action documents, and official regulatory agency correspondence. The challenge is to manage this vast number of requirements to ensure they are appropriately and effectively integrated into CH2M HILL operations. Ensuring compliance with a large number of environmental requirements relies on an organization’s ability to identify, evaluate, communicate, and verify those requirements. To ensure that compliance is maintained, all changes need to be tracked. The CH2M HILL identified that the existing system used to manage environmental requirements was difficult to maintain and that improvements should be made to increase functionality. CH2M HILL established an environmental requirements management procedure and tools to assure that all environmental requirements are effectively and efficiently managed. Having a complete and accurate set of environmental requirements applicable to CH2M HILL operations will promote a more efficient approach to: • Communicating requirements • Planning work • Maintaining work controls • Maintaining compliance

  7. Biotechnology as an alternative for carbon disulfide treatment in air pollution control

    Energy Technology Data Exchange (ETDEWEB)

    Rojo, N.; Gallastegi, G.; Barona, A.; Gurtubay, L.; Elias, A. [Univ. of the Basque Country, Bilbao (Spain). Dept. of Chemical and Environmental Engineering; Gabriel Ibarra-Berastegi [Univ. of the Basque Country, Bilbao (Spain). Dept. of Nuclear Engineering and Fluid Mechanics

    2010-07-01

    The industry demand for CS{sub 2} has changed considerably over the last 2 decades and is expected to increase. This paper discussed the technical and financial feasibility of eliminating carbon disulphide (CS{sub 2}) from exhaust gases use biotechnology. The global emissions of this hazardous air pollutant are estimated to exceed 250,000 tonnes per year. However, the emission range depends on the source. The conventional technologies for treating CS{sub 2} emissions include thermal oxidation, thermo-catalytic processes or incineration. However, these technologies have drawbacks, such as high energy consumption and the generation of secondary by-products that require additional treatment. Recently, biotechnology was touted as an affordable, effective, and ecologically sound alternative to treat waste gases containing CS{sub 2}. Biological technologies based on microorganisms to biodegrade air pollutants overcome many of the disadvantages of conventional techniques and are particularly useful for the removal of relatively low concentrations of pollutants. The main properties, sources, and uses of CS{sub 2} were summarized in this paper along with alternative biotreatments for CS{sub 2}. Several applications of the technical and economical feasibility of biofilters and biotrickling filters were presented. Further research is required before their widespread industrial application. 72 refs., 3 tabs.

  8. 急诊救治“三无”病人中的伦理学要求%The Ethical Requirements in Emergency Treatment of"Three Withouts"Patients

    Institute of Scientific and Technical Information of China (English)

    廖中华; 曹钰; 肖小培; 廖邦兴

    2016-01-01

    阐述了“三无”病人的概念,救治“三无”病人医院及医务人员必须具备的职业道德素质。救治“三无”病人中的伦理学原则问题,救治工作应以人为本,建立并完善社会保障体制,尊重病人知情同意权,医院应主动邀请社会群团组织共同处置。通过社会各界的努力就能达到较好的救治效果,对降低致残率、提高病人的生活质量、减轻社会负担具有积极的现实意义。%This paper has elaborated the concept of"three withouts"patients, and prerequisite professional ethic quality that the hospitals and medi-cal personnels who cure"three withouts"patients. For the ethical principles in treatment of"three withouts"patients, the treatment should be peo-ple-oriented, establishes and perfects the social security system, respects the patients' right of informed consent, the hospital should actively invite other community organizations to manage together. It would be able to achieve a good effect through the efforts from all sectors of society, which is positive and significant to decrease disability rate, improve quality of lfie of patients and reduce social burden.

  9. 基于物联网技术的设施农业自动控制系统%Networking technology based automatic control system of agricultural facilities

    Institute of Scientific and Technical Information of China (English)

    李金莹; 张日升; 杨宏业; 宣传忠

    2014-01-01

    针对农户对基于物联网技术农业大棚的迫切需求,通过农业大棚与物联网技术、WIFI与3G等通信技术相互结合的方式,完成了农业大棚系统总体构架设计的每个模块功能与器件选型,实现了设施农业自动控制系统的整体功能,这样既减少了用户的人力与精力投入,又提高了产品的质量与品质,为用户获得了更多的增值创收;同时通过基于物联网技术的设施农业大棚的推广应用,给经销商带来了源源不断的收益;也促使了当地政府更好的服务于三农,很好的塑造了地方农业品牌与产业升级,更大程度的惠及了广大农户。%Aiming at the urgent demand of farmers on the Internet of things technology based agricultural greenhouse, the greenhouse and the technology of the Internet of things, WIFI and 3G communication technology in conjunction with each other, to complete the function of architecture design of agricultural greenhouse system each module and device selection, the facility agriculture overall function of the automatic control system, thus reducing human and energy user input, and improve the quality of products and quality, for the user to gain more value-added income;at the same time, through the promotion of application of the Internet of things technology facilities based on agricultural greenhouse, brought a revenue stream to the dealer; also prompted the local government to better serve the agriculture, good shape. Brand agricultural and industrial upgrading, greater benefit farmers.

  10. [Development and comparative evaluation of up-converting phosphor technology based lateral flow assay for rapid detection of Yersinia pestis, Bacillus anthracis spore and Brucella spp].

    Science.gov (United States)

    Li, Chunfeng; Zhang, Pingping; Wang, Xiaoying; Liu, Xiao; Zhao, Yong; Sun, Chongyun; Wang, Chengbin; Yang, Ruifu; Zhou, Lei

    2015-01-01

    To develop an up-converting phosphor technology based lateral flow (UPT-LF) assay for rapid and quantitative detection of Yersinia pestis, Bacillus anthracis spore and Brucella spp.and make the comparison with BioThreat Alert (BTA) test strips (Tetracore Inc., USA). Using up-converting phosphor nano-particles (UCP-NPs) as the bio-marker, three double-antibody-sandwich model based UPT-LF strips including Plague-UPT-LF, Anthrax-UPT-LF, Brucella-UPT-LF were prepared and its sensitivity, accuracy, linearity and specificity were determined by detecting 10(10), 10(9), 10(8), 10(7), 10(6), 10(5) and 0 CFU/ml series of concentrations of Y.pestis, B.anthracis, Brucella standards and other 27 kinds of 10(9) CFU/ml series of contrations of bacteria strains.Furthermore, the speed, sensitivity and accuracy of bacteria standards and simulated sample detection were compared between UPT-LF and BTA system. The detection limit of Plague-UPT-LF, Anthrax-UPT-LF and Brucella-LF was 10(5) CFU/ml. The CV of series of bacteria concentrations was ≤ 15%, and the r between lg (T/C-cut-off) and lg (concentration) was 0.996,0.998 and 0.999 (F values were 1 647.57, 743.51 and 1 822.17. All the P values were Brucella-LF were excellent, while that of Anthrax-UPT-LF was a little bit regretful because of non-specific reaction with two isolates of B. subtilis and one B.cereus. On-site evaluation showed the detection time of UPT-LF for all Y.pestis, B.anthracis spore and Brucella spp.was 33, 36 and 37 min, while BTA was 115, 115 and 111 min, which revealed the higher detection speed and sensitivity of UPT-LF comparing with BTA. The negative rate of two methods for blank standard was both 5/5, the sensitivity of UPT-LF for Y.pestis,B.anthracis spore and Brucella spp. was all 10(5) CFU/ml, then BTA was 10(6), 10(6) and 10(5) CFU/ml, respectively. The detection rate of UPT-LF for all three bacteria analog positive samples was 16/16, while BTA for B.anthracis was 7/16 only. The good performance

  11. Development and Evaluation of Up-Converting Phosphor Technology-Based Lateral Flow Assay for Quantitative Detection of NT-proBNP in Blood

    Science.gov (United States)

    Hao, Qingfang; Zou, Deyong; Zhang, Xiaoli; Zhang, Liping; Li, Hongmei; Qiao, Yong; Zhao, Huansheng; Zhou, Lei

    2017-01-01

    A newly assay, up-converting phosphor technology-based lateral flow (UPT-LF) assay, was developed for rapid and quantitative detection of N-terminal fragment of B-type natriuretic peptide precursor (NT-proBNP), one of the most important serum molecular maker of heat failure, in plasma samples as a point of care testing (POCT) method for diagnosis of acute heart failure. Human plasma from 197 patients with acute heart failure and 200 healthy controls was assessed using the UPT-LF assay, in a comparison with a Roche Elecsys assay. The limit of detection of the UPT-LF assay, with a coefficient of variation (CV) of less than 15%, was 116 ng/L, which is lower than the clinical diagnosis cutoff (150 ng/mL). The linear range was 50–35,000 ng/L. The CVs were less than 10% for both UPT-LF and Roche Elecsys assays for plasma samples under different storages, demonstrating the good stability and reproducibility. There are certain linear correlations between the results of UPT-LF and Roche Elecsys assay for EDTA-K2 and heparin-anticoagulated plasma, as well as for serum samples. For UPT-LF assay, there is a significant correlation between the values derived from analysis of EDTA-K2 and heparin-anticoagulated plasma samples (R = 0.995). No statistically significant difference was found between serum and plasma samples for UPT-LF assay. Our results demonstrate that NT-proBNP levels in healthy adults are elevated with age and had a relationship with sex, and with the age increase the NT-proBNP levels of females are significantly higher than those of males (p<0.01). The UPT-LF assay has a high reproducibility, stability, sensitivity, specificity, and is consistent with Roche Elecsys assay, and therefore it could be used as a POCT method for the quantitative detection of NT-proBNP in blood for clinical diagnosis and research of acute heart failure. PMID:28151978

  12. Análise do crescimento das empresas de base tecnológica no Brasil Analysis of growth of technology-based firms in Brazil

    Directory of Open Access Journals (Sweden)

    Daniela Tatiane dos Santos

    2010-01-01

    Full Text Available As empresas de base tecnológica (EBTs são firmas cuja intensa dinâmica inovativa se sustenta em sólidas competências técnicas, havendo em relação a elas uma expectativa de crescimento acelerado. No entanto, mesmo em países desenvolvidos, as evidências demonstram que ritmos de crescimento realmente elevados são mais exceção do que regra. No Brasil, o foco da maioria dos estudos sobre EBTs é diferente, concentrando-se em fatores que restringem seu sucesso, como experiência gerencial e disponibilidade de capital. Baseando-se em ampla pesquisa de campo e num indicador robusto de crescimento empresarial, este artigo pretende abordar a questão da expansão dessas empresas, analisando sua relação com elementos que as caracterizam, como grau de consolidação, inserção de mercado e apoio por políticas públicas. Entre os resultados, destacam-se uma taxa de crescimento que, embora muito variada, é geralmente expressiva - mediana de 15,3% - e não se relaciona diretamente com a intensidade do apoio por políticas públicas.Technology-Based Firms (TBFs are companies with intensive innovation dynamics based on technical competences, and for which high growth rates are expected. Nevertheless, even in developed countries, the evidence suggests that significantly high growth rates are more the exception than the rule. In Brazil, most studies on TBFs focus on factors that limit their success, such as managerial experience and capital availability. Based on extensive field research and on a reliable enterprise growth rate indicator, this article aims to evaluate the expansion of those firms, analyzing its relation to key elements such as degree of consolidation, market insertion, and public policy support. We found a growth rate which, although widely varied amongst firms, was significant and was not directly related to the amount of public policy support.

  13. Hardware Trojan Detection Technology Based on Probabilistic Signature%基于概率签名的硬件木马检测技术

    Institute of Scientific and Technical Information of China (English)

    郑朝霞; 李一帆; 余良; 田园; 刘政林

    2014-01-01

    Trojan circuits can bypass traditional defensive techniques as they occupy a layer below the entire software stack. This paper proposes a hardware trojan detection technology based on probabilistic signature. Based on logic detection technology, using random and hypothesis algorithm, this paper constructs the probability signature of circuits(Boolean functions), as the unique identifier template. When the signature of circuit under test does not match the template, an alarm is launched. It designs two circuits that implement full adder and AES encryption, and then they are implanted with common hardware Trojan. It makes in-depth theoretical analysis and research on whether the probabilistic signature of the circuits implanted with hardware Trojans is changed in comparison with the two kinds of original circuits. It tests the circuits based on FPGA platform via probabilistic method. As a result, it is verified that based on the probability signature, it can easily achieve a 95%level of confidence on the detection of hardware Trojans implanted into the combinational logic circuits.%针对集成电路芯片被植入硬件木马后带来的安全问题,提出一种基于概率签名的硬件木马检测技术。通过逻辑功能检测,采用随机算法构建芯片电路(布尔函数)的概率签名,作为唯一的识别符模板,当被测电路的签名与模板不匹配时发出告警。设计全加器和AES加密2款电路,植入常见硬件木马并进行攻击实验,对这2种电路的原始电路以及植入硬件木马后电路的概率签名是否发生改变进行理论分析与研究。采用统计学参数估计法在 FPGA 平台进行实验,结果表明,该概率签名技术能检测出一般规模组合逻辑电路中植入的硬件木马,置信度达到95%。

  14. Study Protocol of MINI SALTEN: a technology-based multi-component intervention in the school environment targeting healthy habits of first grade children and their parents.

    Science.gov (United States)

    Kovalskys, Irina; Rausch Herscovici, Cecile; Indart Rougier, Paula; De Gregorio, María José; Zonis, Luciana; Orellana, Liliana

    2017-05-06

    parsimonious model for each outcome will be reported. The False Discovery Rate criterion will be used to correct for multiple testing in non-planned analyses. It is a pioneer assessment of the impact of a technology-based virtual intervention and a school-based PA program, designed to prevent obesity, and involving the parents at public schools of Buenos Aires. Current Controlled Trials ISRCTN58093412 . Registered March 14th, 2016 (retrospectively registered).

  15. 基于NoSQL数据库的大数据查询技术%Large data query technology based on NoSQL database

    Institute of Scientific and Technical Information of China (English)

    忻禾登

    2016-01-01

    Provide a consumer with the continuous development and innovation of science and technology, the Internet is gradually people, entertainment and communication as the core platform for various. At the same time, more and more data also continue to emerge, these data showing various characteristics, form and content are more diverse. Therefore, based on the framework of NoSQL data query technology was born. And the advanced technology gradually become hot topics in academic research. This paper focuses on the classification of NoSQL database from the, characteristics of NoSQL framework of data query technology based on, the advantages and limitations of the theory.%随着科学技术的不断发展和创新,网络时代迎来新高潮,互联网逐渐为老百姓提供了一个消费、娱乐与沟通为一体的核心平台。与此同时,越来越多的数据也在不断涌现,这些数据呈现出各种特点,形式和内容都是多样化的。可以认为,原始的、较为不成熟的关系型数据库是无法再满足社会发展和人类自身需要的。因此,基于基于NoSQL框架的数据查询技术由此诞生,而且这一先进技术逐步成为学界研究的热点领域。本文重点从NoSQL数据库的分类、基于NoSQL框架的数据查询技术的特点、基于NoSQL框架的数据查询技术的优势和长处以及不足等方面进行论述。

  16. Faulty assumptions for repository requirements

    Energy Technology Data Exchange (ETDEWEB)

    Sutcliffe, W G

    1999-06-03

    Long term performance requirements for a geologic repository for spent nuclear fuel and high-level waste are based on assumptions concerning water use and subsequent deaths from cancer due to ingesting water contaminated with radio isotopes ten thousand years in the future. This paper argues that the assumptions underlying these requirements are faulty for a number of reasons. First, in light of the inevitable technological progress, including efficient desalination of water, over the next ten thousand years, it is inconceivable that a future society would drill for water near a repository. Second, even today we would not use water without testing its purity. Third, today many types of cancer are curable, and with the rapid progress in medical technology in general, and the prevention and treatment of cancer in particular, it is improbable that cancer caused by ingesting contaminated water will be a sign&ant killer in the far future. This paper reviews the performance requirements for geological repositories and comments on the difficulties in proving compliance in the face of inherent uncertainties. The already tiny long-term risk posed by a geologic repository is presented and contrasted with contemporary every day risks. A number of examples of technological progress, including cancer treatments, are advanced. The real and significant costs resulting from the overly conservative requirements are then assessed. Examples are given of how money (and political capital) could be put to much better use to save lives today and in the future. It is concluded that although a repository represents essentially no long-term risk, monitored retrievable dry storage (above or below ground) is the current best alternative for spent fuel and high-level nuclear waste.

  17. 19 CFR 10.706 - Declaration not required.

    Science.gov (United States)

    2010-04-01

    ... TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. United States-Jordan Free Trade Agreement Import Requirements § 10.706 Declaration not required. (a) General. Except as otherwise provided... of the claim for preferential tariff treatment....

  18. 19 CFR 10.586 - Certification not required.

    Science.gov (United States)

    2010-04-01

    ...-United States Free Trade Agreement Import Requirements § 10.586 Certification not required. (a) General... copy of the certification will result in denial of the claim for preferential tariff treatment....

  19. Writing testable software requirements

    Energy Technology Data Exchange (ETDEWEB)

    Knirk, D. [Sandia National Labs., Albuquerque, NM (United States)

    1997-11-01

    This tutorial identifies common problems in analyzing requirements in the problem and constructing a written specification of what the software is to do. It deals with two main problem areas: identifying and describing problem requirements, and analyzing and describing behavior specifications.

  20. Ecodesign requirements for televisions

    DEFF Research Database (Denmark)

    Huulgaard, Rikke Dorothea; Dalgaard, Randi; Merciai, Stefano

    2013-01-01

    Purpose This paper concerns the Ecodesign Directive (2009/125/EC) and the implementing measures (IM) in which ecodesign requirements are set up for energy-using and energy-related products. Previous studies have found that the requirements have a unilateral focus on energy consumption and the use...

  1. Getting the Requirements Right

    Science.gov (United States)

    2015-08-01

    27 Defense AT&L: July–August 2015 Getting the Requirements Right Sean J. Stackley, USN Stackley is Assistant Secretary of the Navy for Research...getting the requirements right . The author can be contacted through brian.a.metcalf@navy.mil. We’re Looking for a Few Good Authors Got opinions to

  2. Lexicographic Treatment of

    African Journals Online (AJOL)

    user

    ... in terms of similarities versus differences, following an amalgamated approach. .... (d) non-cognates: words with the same meaning but clear difference in form ... find their place in an amalgamated approach but require separate treatment for.

  3. Making Decisions about Treatment

    Science.gov (United States)

    ... contains the logic required to handle Ajax powered Gravity Forms. Articles Health care reform HCV care & treatment Hepatitis C ... ProjectInform CA's laws have not caught up w/ science! @JerryBrownGov please ...

  4. Urban Sewage Sludge, Sustainability, and Transition for Eco-City: Multi-Criteria Sustainability Assessment of Technologies based on Best-Worst Method

    DEFF Research Database (Denmark)

    Ren, Jingzheng; Liang, Hanwei; Chan, Felix T. S.

    2016-01-01

    The treatment of urban sewage sludge is of vital importance for mitigating the risks of environmental contaminations, and the negative effects on human health. However, there are usually various different technologies for the treatment of urban sewage sludge; thus, it is difficult for decision-ma...

  5. Cumulative input/output balance of a mechanical-biological waste treatment plant. Comparison of construction material requirements, operating energy expenditure, and the requirement of auxiliary materials in comparison with waste combustion; Kumulative Bilanzierung der mechanisch-biologischen Restabfallbehandlung - Baumaterialien und betrieblicher Energie- und Hilfsstoffaufwand im Vergleich zur Muellverbrennung

    Energy Technology Data Exchange (ETDEWEB)

    Wallmann, R.; Fricke, K. [Ingenieurgemeinschaft Witzenhausen (Germany); Vogtmann, H. [Hessisches Landesamt fuer Regionalentwicklung und Landwirtschaft, Kassel (Germany)

    1998-12-31

    The study strikes a cumulative input/output balance of an existing waste conditioning plant considering not only operating energy demand but also the required construction materials for erecting the plant. In operation since 1996, the waste conditioning plant is entirely state of the art; hence the data obtained are up to date. The results are compared with relevant results for a waste processing plant and evaluated. (orig.) [Deutsch] Im Rahmen der vorliegenden Untersuchung erfolgt eine kumulative Bilanzierung einer bestehenden MBA-Anlage, wobei neben den betrieblichen Energieaufwendungen auch die Baumaterialien zur Herstellung der Anlage beruecksichtigt werden. Die seit 1996 in Betrieb befindliche Abfallbehandlungsanlage entspricht weitestgehend dem Stand der Technik der MBA, wodurch die Aktualitaet der Daten gegeben ist. Die Ergebnisse der Bilanzierung werden im Vergleich zu einer MVA dargestellt und bewertet. (orig.)

  6. 基于知识网络的教育技术实验平台的设计与实现%Design and implementation of experimental platform with educational technology based on the knowledge network

    Institute of Scientific and Technical Information of China (English)

    陈文沛

    2014-01-01

    总结了教育技术实验教学存在的主要问题,分析了基于知识网络的教育技术实验平台的优越性,介绍了基于知识网络的教育技术实验平台的设计与实现过程。%In this paper, the main problems in experimental teaching with educational technology are introduced; the advantages of experimental platform with educational technology based on the knowledge network are analyzed; design and implementation of experimental platform with educational technology based on the knowledge network are introduced at last.

  7. Structural requirements of some 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide derivatives as poly (ADP-ribose) polymerase (PARP) for the treatment of cancer: QSAR approach.

    Science.gov (United States)

    Sharma, Mukesh C

    2014-09-02

    The present study is aimed to elucidate the structural features of substituted 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide required for poly (ADP-ribose) polymerase inhibition and to obtain predictive 2D QSAR models to guide the rational synthesis of novel poly (ADP-ribose) polymerase inhibitors. The statistical analysis has shown that excellent results are obtained by using partial least regression based on simulated annealing method. The best model was selected based on the highest correlation coefficient r(2) = 0.8590 and cross validated squared correlation coefficient q(2) = 0.7875 with external predictive ability of pred_r(2) = 0.7407 was developed by stepwise PLS method with the descriptors like T_N_F_1, SdsCHcount, and Rotatable Bond Count. The generated models provide insight into the influence of various interactive fields on the activity and, thus, can help in designing and forecasting the inhibition activity of novel (ADP-ribose) polymerase molecules.

  8. Structural Requirements of Some 2-(1-Propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide Derivatives as Poly (ADP-Ribose) Polymerase (PARP) for the Treatment of Cancer: QSAR Approach.

    Science.gov (United States)

    Sharma, Mukesh C

    2016-03-01

    The present study is aimed to elucidate the structural features of substituted 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide required for poly (ADP-ribose) polymerase inhibition and to obtain predictive 2D QSAR models to guide the rational synthesis of novel poly (ADP-ribose) polymerase inhibitors. The statistical analysis has shown that excellent results are obtained by using partial least regression based on simulated annealing method. The best model was selected based on the highest correlation coefficient r (2) = 0.8590, and cross-validated squared correlation coefficient q (2) = 0.7875 with external predictive ability of [Formula: see text] was developed by stepwise PLS method with the descriptors like T_N_F_1, SdsCHcount, and Rotatable Bond Count. The generated models provide insight into the influence of various interactive fields on the activity and, thus, can help in designing and forecasting the inhibition activity of novel (ADP-ribose) polymerase molecules.

  9. Requirements in engineering projects

    CERN Document Server

    Fernandes, João M

    2016-01-01

    This book focuses on various topics related to engineering and management of requirements, in particular elicitation, negotiation, prioritisation, and documentation (whether with natural languages or with graphical models). The book provides methods and techniques that help to characterise, in a systematic manner, the requirements of the intended engineering system.  It was written with the goal of being adopted as the main text for courses on requirements engineering, or as a strong reference to the topics of requirements in courses with a broader scope. It can also be used in vocational courses, for professionals interested in the software and information systems domain.   Readers who have finished this book will be able to: - establish and plan a requirements engineering process within the development of complex engineering systems; - define and identify the types of relevant requirements in engineering projects; - choose and apply the most appropriate techniques to elicit the requirements of a giv...

  10. 基于超文本标记语言的信息隐藏方法研究与实现%Research and Implementation of the Information Hiding Technology Based on Hypertext Markup Language

    Institute of Scientific and Technical Information of China (English)

    吴大胜

    2011-01-01

    This paper analyzes the structure of the hypertext files,proposes a new information hiding technology based on hypertext markup language,and analyze the algorithm.%通过分析超文本的文件结构,提出了一种基于超文本标记语言的信息隐藏方法,并对该算法进行了分析。

  11. Creativity in Requirement Identification

    DEFF Research Database (Denmark)

    Sørensen, Lene Tolstrup; Olesen, Henning

    Traditional requirements engineering focuses mainly on analysis and elicitation. However, current trends in new system, device and software are towards involving all stakeholders in the early stages of the engineering process to define the user requirements. Creativity is here seen as a major...... keystone in this process in order to open up stakeholder's mind to new technologies, which do not yet exist. This paper dis-cusses the application of creativity in the requirements process and illustrate through cases from the MAGNET and MAGNET Beyond projects....

  12. From requirements to Java in a snap model-driven requirements engineering in practice

    CERN Document Server

    Smialek, Michal

    2015-01-01

    This book provides a coherent methodology for Model-Driven Requirements Engineering which stresses the systematic treatment of requirements within the realm of modelling and model transformations. The underlying basic assumption is that detailed requirements models are used as first-class artefacts playing a direct role in constructing software. To this end, the book presents the Requirements Specification Language (RSL) that allows precision and formality, which eventually permits automation of the process of turning requirements into a working system by applying model transformations and co

  13. Science in Requirements Engineering

    National Research Council Canada - National Science Library

    Suhaimi Jaafar

    2014-01-01

    Based on a review of the articles about methodological principles, and some research classifications, in this work an overview of the nature and status of science in Requirements Engineering is done...

  14. Ecodesign requirements for televisions

    DEFF Research Database (Denmark)

    Huulgaard, Rikke Dorothea; Dalgaard, Randi; Merciai, Stefano

    2013-01-01

    to analyse if other environmental hotspots and life cycle phases should be included in the requirements in the IM of the Ecodesign Directive besides energy consumption in the use phase analysis. Methods The consequential approach is used. The data for the LCA have been gathered from two manufacturers of TVs......Purpose This paper concerns the Ecodesign Directive (2009/125/EC) and the implementing measures (IM) in which ecodesign requirements are set up for energy-using and energy-related products. Previous studies have found that the requirements have a unilateral focus on energy consumption and the use...... phase. This is not in line with the scientific understanding of ecodesign, where attention should be put on all life cycle phases and all relevant environmental impact categories. This study focuses on the requirements for televisions (TV). A life cycle assessment (LCA) is carried out on two TVs...

  15. Energy, material and land requirement of a fusion plant

    DEFF Research Database (Denmark)

    Schleisner, Liselotte; Hamacher, T.; Cabal, H.

    2001-01-01

    The energy and material necessary to construct a power plant and the land covered by the plant are indicators for the ‘consumption’ of environment by a certain technology. Based on current knowledge, estimations show that the material necessary to construct a fusion plant will exceed the material...... requirement of a fission plant by a factor of two. The material requirement for a fusion plant is roughly 2000 t/MW and little less than 1000 t/MW for a fission plant. The land requirement for a fusion plant is roughly 300 m2/MW and the land requirement for a fission plant is a little less than 200 m2/MW....... The energy pay back time, defined later in Section 6, is little more than half a year for a fusion plant with capacity 1 GWe. Only the electrical energy is accounted for as released energy not the thermal energy. In all these indicators, fusion compares well with conventional technologies while it consumes...

  16. Cradle Cap: Treatment

    Science.gov (United States)

    Cradle cap Treatment Cradle cap usually doesn't require medical treatment. It clears up on its own within a few months. In the meantime, wash ... tips can help you control and manage cradle cap. Gently rub your baby's scalp with your fingers ...

  17. Innovations for Requirements Engineering

    Science.gov (United States)

    2008-01-01

    for the Evolution of Requirements Models Allyson Hoss, Doris Carver 129 Text Classification and Machine Learning Support for Requirements...Hoss and Doris L. Carver Department of Computer Science Louisiana State University Baton Rouge, LA 70803, USA ahoss1@lsu.edu, dcarver@lsu.edu...Algunas reflexiones en el 40° aniversario de los Sistemas de Gerencia de Bases de Datos, ARTech, 2003 www.genexus.com/whitepapers 13. Humphrey

  18. BRD usability requirements

    Energy Technology Data Exchange (ETDEWEB)

    Deshpande, Alina [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-03-12

    This document describes the usability requirements for the Biosurveillance resource directory (BRD); that is, who will be using the tool and what tasks they will be using it for. It does not include information on technical implementation (e.g., whether specific information is contained in the database or pulled on demand from other sources). It also avoids specific design ideas (such as widget descriptions) unless they are necessary to illustrate a requirement.

  19. Uniform Requirements for Manuscripts

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    @@ Introduction The Uniform requirements are instructions to authors on how to prepare manuscripts.If authors prepare their manuscripts in the style specified in these requirements, editors of the participating journals will not return the manuscripts for changes in style before considering them for publication.In the publishing process, however, the journals may alter accepted manuscripts to conform with details of their publication styles.

  20. CLIC Detector Power Requirements

    CERN Document Server

    Gaddi, A

    2013-01-01

    An estimate for the CLIC detector power requirements is outlined starting from the available data on power consumptions of the four LHC experiments and considering the differences between a typical LHC Detector (CMS) and the CLIC baseline detector concept. In particular the impact of the power pulsing scheme for the CLIC Detector electronics on the overall detector consumption is considered. The document will be updated with the requirements of the sub-detector electronics once they are more defined.

  1. Issues in Requirements Elicitation

    Science.gov (United States)

    1992-09-01

    oriented domain analysis ( FODA ) continues that the re- quirements analyst uses the products of domain analysis when implementing a new system [Kang 90, p...5]. Therefore, FODA does have applicability to requirements elicitation, and will be overviewed in this section. All requirements originate with the...information. For example, with FODA both an entity relationship model and features model are created. The entity relationship model is particularly useful

  2. Utility requirements for fusion

    Energy Technology Data Exchange (ETDEWEB)

    Vondrasek, R.J.

    1982-02-01

    This report describes work done and results obtained during performance of Task 1 of a study of Utility Requirements and Criteria for Fusion Options. The work consisted of developing a list of utility requirements for fusion optics containing definition of the requirements and showing their relative importance to the utility industry. The project team members developed a preliminary list which was refined by discussions and literature searches. The refined list was recast as a questionnaire which was sent to a substantial portion of the utility industry in this country. Forty-three questionnaire recipients responded including thirty-two utilities. A workshop was held to develop a revised requirements list using the survey responses as a major input. The list prepared by the workshop was further refined by a panel consisting of vice presidents of the three project team firms. The results of the study indicate that in addition to considering the cost of energy for a power plant, utilities consider twenty-three other requirements. Four of the requirements were judged to be vital to plant acceptability: Plant Capital Cost, Financial Liability, Plant Safety and Licensability.

  3. Final report on grand challenge LDRD project : a revolution in lighting : building the science and technology base for ultra-efficient solid-state lighting.

    Energy Technology Data Exchange (ETDEWEB)

    Copeland, Robert Guild; Mitchell, Christine Charlotte; Follstaedt, David Martin; Lee, Stephen Roger; Shul, Randy John; Fischer, Arthur Joseph; Chow, Weng Wah Dr.; Myers, Samuel Maxwell, Jr.; Thoma, Steven George; Gee, James Martin; Coltrin, Michael Elliott; Burdick, Brent A.; Salamone, Angelo, L., Jr.; Hadley, G. Ronald; Elliott, Russell D.; Campbell, Jonathan M.; Abrams, Billie Lynn; Wendt, Joel Robert; Pawlowski, Roger Patrick; Simpson, Regina Lynn; Kurtz, Steven Ross; Cole, Phillip James; Fullmer, Kristine Wanta; Seager, Carleton Hoover; Bogart, Katherine Huderle Andersen; Biefeld, Robert Malcolm; Kerley, Thomas M.; Norman, Adam K.; Tallant, David Robert; Woessner, Stephen Matthew; Figiel, Jeffrey James; Moffat, Harry K.; Provencio, Paula Polyak; Emerson, John Allen; Kaplar, Robert James; Wilcoxon, Jess Patrick; Waldrip, Karen Elizabeth; Rohwer, Lauren Elizabeth Shea; Cross, Karen Charlene; Wright, Alan Francis; Gonzales, Rene Marie; Salinger, Andrew Gerhard; Crawford, Mary Hagerott; Garcia, Marie L.; Allen, Mark S.; Southwell, Edwin T. (Perspectives, Sedona, AZ); Bauer, Tom M.; Monson, Mary Ann; Tsao, Jeffrey Yeenien; Creighton, James Randall; Allerman, Andrew Alan; Simmons, Jerry A.; Boyack, Kevin W.; Jones, Eric Daniel; Moran, Michael P.; Pinzon, Marcia J. (Perspectives, Sedona, AZ); Pinson, Ariane O. (Perspectives, Sedona, AZ); Miksovic, Ann E. (Perspectives, Sedona, AZ); Wang, George T.; Ashby, Carol Iris Hill; Missert, Nancy A.; Koleske, Daniel David; Rahal, Nabeel M.

    2004-06-01

    This SAND report is the final report on Sandia's Grand Challenge LDRD Project 27328, 'A Revolution in Lighting -- Building the Science and Technology Base for Ultra-Efficient Solid-state Lighting.' This project, which for brevity we refer to as the SSL GCLDRD, is considered one of Sandia's most successful GCLDRDs. As a result, this report reviews not only technical highlights, but also the genesis of the idea for Solid-state Lighting (SSL), the initiation of the SSL GCLDRD, and the goals, scope, success metrics, and evolution of the SSL GCLDRD over the course of its life. One way in which the SSL GCLDRD was different from other GCLDRDs was that it coincided with a larger effort by the SSL community - primarily industrial companies investing in SSL, but also universities, trade organizations, and other Department of Energy (DOE) national laboratories - to support a national initiative in SSL R&D. Sandia was a major player in publicizing the tremendous energy savings potential of SSL, and in helping to develop, unify and support community consensus for such an initiative. Hence, our activities in this area, discussed in Chapter 6, were substantial: white papers; SSL technology workshops and roadmaps; support for the Optoelectronics Industry Development Association (OIDA), DOE and Senator Bingaman's office; extensive public relations and media activities; and a worldwide SSL community website. Many science and technology advances and breakthroughs were also enabled under this GCLDRD, resulting in: 55 publications; 124 presentations; 10 book chapters and reports; 5 U.S. patent applications including 1 already issued; and 14 patent disclosures not yet applied for. Twenty-six invited talks were given, at prestigious venues such as the American Physical Society Meeting, the Materials Research Society Meeting, the AVS International Symposium, and the Electrochemical Society Meeting. This report contains a summary of these science and technology

  4. 基于函数截获的游戏内置广告集成技术%IN-GAME ADVERTISING INTEGRATION TECHNOLOGY BASED ON FUNCTION INTERCEPTION

    Institute of Scientific and Technical Information of China (English)

    郭冰鉴; 张天乐; 梁思毓; 姜忠鼎

    2012-01-01

    With the popularity of the Internet,online advertising industry has made rapid progress. In-game advertising becomes a new form of online advertising. Due to the large number of the players,the media value of online game is growing,and the related in-game advertising integration technology has gained some progress. Current in-game advertising technology uses SDK integration approach and needs to modify a lot of source codes of games. This integration technology is high coupling between the advertising logic and the game logic, therefore it is difficult to implement complex interactive advertisement. This paper proposes an in-game advertising integration technology based on function interception to overcome the deficiency of existing SDK advertising integration technology. The technology presented in this paper intercepts and displaces 3-D graphics rendering functions,dynamically executes scripts program,it integrates image, video,3-D object and interactive clicking advertisement into game scenes without modifying the source code of game client. Experimental results show that it does not affect the fluency of the online game after integrating advertisement in online game scenes by function interception, and the game scene keeps high refreshing frame rates.%伴随互联网的普及,互联网广告得到快速发展,游戏内置广告已成为一种新兴的互联网广告形式.由于玩家数量庞大,网络游戏的媒体价值不断增长,与其相关的广告集成技术也获得一定发展.现有游戏内置广告技术采用SDK的集成方式,需要大量修改网络游戏源代码,广告逻辑与游戏逻辑耦合度高,难以实现复杂的交互式广告.提出一种基于函数截获的游戏内置广告集成技术,克服现有SDK广告集成技术的不足.该技术截获并替换三维图形绘制函数,动态执行脚本[¨]程序,在不修改游戏客户端源代码的情况下,集成图像、视频、三维物体和动态交互式点击广告.实验

  5. Digestible lysine requirements of broilers

    Directory of Open Access Journals (Sweden)

    LEP Bernal

    2014-03-01

    Full Text Available Modern broilers have been submitted to continuous genetic improvement, and therefore, their nutritional requirements must be constantly updated to ensure their performance. Two experiments were carried out to evaluate different digestible lysine levels for starter (1021 days and grower (22-35 days phases. The experiments were carried out with male and female Cobb 500 broilers, distributed according to a randomized block experimental design in a 5x2 factorial arrangement (5 increasing digestible lysine levels x 2 sexes, totaling 10 treatments, with 8 replicates of 22 and 20 birds during the starter and grower phase, respectively. Digestible lysine levels of 1.06, 1.12, 1.18, 1.24, and 1.30 were used in the starter diets (10-21 days and 0.9, 0.98, 1.04, 1.10, and 1.16% in the grower diets (22-35 days. Based on the statistical analyses of the evaluated performance parameters, digestible lysine requirements for maximum performance were determined as 1.22% for males and 1.24% for females in the starter phase, and 1.16% for both sexes in the grower phase. Carcass and performance results indicate that digestible lysine requirements vary with sex and evaluated production parameter. Considering the most relevant broiler production parameters, in 22- to 35-d-old males, digestible lysine requirement for breast meat yield (1.16% was higher than those for feed conversion ratio (1.07% and weight gain (1.05%.

  6. Hyperbaric treatment

    Science.gov (United States)

    Amoroso, Michael T.

    1990-01-01

    Viewgraphs on hyperbaric treatment are presented. Topics covered include: hyperbaric treatment - purpose; decompression sickness; sources of decompression sickness; physical description; forms of decompression sickness; hyperbaric treatment of decompression sickness; and duration of treatment.

  7. NP Science Network Requirements

    Energy Technology Data Exchange (ETDEWEB)

    Dart, Eli [Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States); Rotman, Lauren [Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States); Tierney, Brian [Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

    2011-08-26

    The Energy Sciences Network (ESnet) is the primary provider of network connectivity for the U.S. Department of Energy (DOE) Office of Science (SC), the single largest supporter of basic research in the physical sciences in the United States. To support SC programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs it serves. This focus has helped ESnet to be a highly successful enabler of scientific discovery for over 20 years. In August 2011, ESnet and the Office of Nuclear Physics (NP), of the DOE SC, organized a workshop to characterize the networking requirements of the programs funded by NP. The requirements identified at the workshop are summarized in the Findings section, and are described in more detail in the body of the report.

  8. Incontinence Treatment: Newer Treatment Options

    Science.gov (United States)

    ... Bowel Incontinence Signs & Symptoms Symptoms of Incontinence Diarrhea Treatment Lifestyle Changes Dietary Tips Medication Bowel Management Biofeedback Surgical Treatments Newer Treatment Options Tips on Finding a Doctor ...

  9. [Women's experiences and care practices in the cancer treatment process].

    Science.gov (United States)

    Oliveira, Pricilla Emmanuelly; Guimarães, Sílvia Maria Ferreira

    2015-07-01

    This article seeks to understand the viewpoint of cancer patients about the disease process and the therapeutic procedures that they experience. Cancer treatments provoke a series of physical and emotional consequences in patients. Thus, patients undergo a restructuring of life and establish mechanisms to "take care of themselves." The methodology used was an ethnographic approach through interviews, field notes and participant observation. The ethnographic approach revealed how these women being given conventional treatment in a given hospital create shared care technologies based on sociability.

  10. Army Sociocultural Performance Requirements

    Science.gov (United States)

    2014-06-01

    L., Crafts, J. L., & Brooks, J. E. (July 1995). Intercultural communication requirements for Special Forces teams. (Study Report 1683). Arlington... Communication Uses alternative, sometimes novel, methods to communicate when verbal language is not shared; conveys information about mood, intent...status, and demeanor via gestures, tone of voice, and facial expressions; improvises communication techniques as necessary. WI Works with Interpreters

  11. Requirements for Xenon International

    Energy Technology Data Exchange (ETDEWEB)

    Hayes, James C.; Ely, James H.

    2013-09-26

    This document defines the requirements for the new Xenon International radioxenon system. The output of this project will be a Pacific Northwest National Laboratory (PNNL) developed prototype and a manufacturer-developed production prototype. The two prototypes are intended to be as close to matching as possible; this will be facilitated by overlapping development cycles and open communication between PNNL and the manufacturer.

  12. Requirements for Xenon International

    Energy Technology Data Exchange (ETDEWEB)

    Hayes, James C.; Ely, James H.; Haas, Derek A.; Harper, Warren W.; Heimbigner, Tom R.; Hubbard, Charles W.; Humble, Paul H.; Madison, Jill C.; Morris, Scott J.; Panisko, Mark E.; Ripplinger, Mike D.; Stewart, Timothy L.

    2015-12-30

    This document defines the requirements for the new Xenon International radioxenon system. The output of this project will be a Pacific Northwest National Laboratory (PNNL) developed prototype and a manufacturer-developed production prototype. The two prototypes are intended to be as close to matching as possible; this will be facilitated by overlapping development cycles and open communication between PNNL and the manufacturer.

  13. Lunar base construction requirements

    Science.gov (United States)

    Jolly, Steve; Helleckson, Brent

    1990-01-01

    The following viewgraph presentation is a review of the Lunar Base Constructibility Study carried out in the spring and summer of 1990. The objective of the study was to develop a method for evaluating the constructibility of Phase A proposals to build facilities on orbit or on extraterrestrial surfaces. Space construction was broadly defined as all forms of assembly, disassembly, connection, disconnection, deployment, stowage, excavation, emplacement, activation, test, transportation, etc., required to create facilities in orbit and on the surfaces of other celestial bodies. It was discovered that decisions made in the face of stated and unstated assumptions early in the design process (commonly called Phase A) can lock in non-optimal construction methods. Often, in order to construct the design, alterations must be made to the design during much later phases of the project. Such 'fixes' can be very difficult, expensive, or perhaps impossible. Assessing constructibility should thus be a part of the iterative design process, starting with the Phase A studies and continuing through production. This study assumes that there exists a minimum set of key construction requirements (i.e., questions whose answers form the set of discriminators) that must be implied or specified in order to assess the constructibility of the design. This set of construction requirements constitutes a 'constructibility filter' which then becomes part of the iterative design process. Five inherently different, dichotomous design reference missions were used in the extraction of these requirements to assure the depth and breath of the list.

  14. INDECT Advanced Security Requirements

    CERN Document Server

    Uruena, Manuel; Martinez, Maria; Niemiec, Marcin; Stoianov, Nikolai

    2010-01-01

    This paper reviews the requirements for the security mechanisms that are currently being developed in the framework of the European research project INDECT. An overview of features for integrated technologies such as Virtual Private Networks (VPNs), Cryptographic Algorithms, Quantum Cryptography, Federated ID Management and Secure Mobile Ad-hoc networking are described together with their expected use in INDECT.

  15. Protein Requirements during Aging

    Directory of Open Access Journals (Sweden)

    Glenda Courtney-Martin

    2016-08-01

    Full Text Available Protein recommendations for elderly, both men and women, are based on nitrogen balance studies. They are set at 0.66 and 0.8 g/kg/day as the estimated average requirement (EAR and recommended dietary allowance (RDA, respectively, similar to young adults. This recommendation is based on single linear regression of available nitrogen balance data obtained at test protein intakes close to or below zero balance. Using the indicator amino acid oxidation (IAAO method, we estimated the protein requirement in young adults and in both elderly men and women to be 0.9 and 1.2 g/kg/day as the EAR and RDA, respectively. This suggests that there is no difference in requirement on a gender basis or on a per kg body weight basis between younger and older adults. The requirement estimates however are ~40% higher than the current protein recommendations on a body weight basis. They are also 40% higher than our estimates in young men when calculated on the basis of fat free mass. Thus, current recommendations may need to be re-assessed. Potential rationale for this difference includes a decreased sensitivity to dietary amino acids and increased insulin resistance in the elderly compared with younger individuals.

  16. Data Crosscutting Requirements Review

    Energy Technology Data Exchange (ETDEWEB)

    Kleese van Dam, Kerstin [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Shoshani, Arie [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Plata, Charity [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2013-04-01

    In April 2013, a diverse group of researchers from the U.S. Department of Energy (DOE) scientific community assembled to assess data requirements associated with DOE-sponsored scientific facilities and large-scale experiments. Participants in the review included facilities staff, program managers, and scientific experts from the offices of Basic Energy Sciences, Biological and Environmental Research, High Energy Physics, and Advanced Scientific Computing Research. As part of the meeting, review participants discussed key issues associated with three distinct aspects of the data challenge: 1) processing, 2) management, and 3) analysis. These discussions identified commonalities and differences among the needs of varied scientific communities. They also helped to articulate gaps between current approaches and future needs, as well as the research advances that will be required to close these gaps. Moreover, the review provided a rare opportunity for experts from across the Office of Science to learn about their collective expertise, challenges, and opportunities. The "Data Crosscutting Requirements Review" generated specific findings and recommendations for addressing large-scale data crosscutting requirements.

  17. User Requirements for Wireless

    DEFF Research Database (Denmark)

    technologies or software has been developed. A variety of user requirements are provided illustrating the effect of changing the targeted user group with respect to age,; to the context and the different technologies or software as well as to the difference in viewpoint on ways of involving users...

  18. TRACER - TRACING AND CONTROL OF ENGINEERING REQUIREMENTS

    Science.gov (United States)

    Turner, P. R.

    1994-01-01

    TRACER (Tracing and Control of Engineering Requirements) is a database/word processing system created to document and maintain the order of both requirements and descriptive material associated with an engineering project. A set of hierarchical documents are normally generated for a project whereby the requirements of the higher level documents levy requirements on the same level or lower level documents. Traditionally, the requirements are handled almost entirely by manual paper methods. The problem with a typical paper system, however, is that requirements written and changed continuously in different areas lead to misunderstandings and noncompliance. The purpose of TRACER is to automate the capture, tracing, reviewing, and managing of requirements for an engineering project. The engineering project still requires communications, negotiations, interactions, and iterations among people and organizations, but TRACER promotes succinct and precise identification and treatment of real requirements separate from the descriptive prose in a document. TRACER permits the documentation of an engineering project's requirements and progress in a logical, controllable, traceable manner. TRACER's attributes include the presentation of current requirements and status from any linked computer terminal and the ability to differentiate headers and descriptive material from the requirements. Related requirements can be linked and traced. The program also enables portions of documents to be printed, individual approval and release of requirements, and the tracing of requirements down into the equipment specification. Requirement "links" can be made "pending" and invisible to others until the pending link is made "binding". Individuals affected by linked requirements can be notified of significant changes with acknowledgement of the changes required. An unlimited number of documents can be created for a project and an ASCII import feature permits existing documents to be incorporated

  19. TRACER - TRACING AND CONTROL OF ENGINEERING REQUIREMENTS

    Science.gov (United States)

    Turner, P. R.

    1994-01-01

    TRACER (Tracing and Control of Engineering Requirements) is a database/word processing system created to document and maintain the order of both requirements and descriptive material associated with an engineering project. A set of hierarchical documents are normally generated for a project whereby the requirements of the higher level documents levy requirements on the same level or lower level documents. Traditionally, the requirements are handled almost entirely by manual paper methods. The problem with a typical paper system, however, is that requirements written and changed continuously in different areas lead to misunderstandings and noncompliance. The purpose of TRACER is to automate the capture, tracing, reviewing, and managing of requirements for an engineering project. The engineering project still requires communications, negotiations, interactions, and iterations among people and organizations, but TRACER promotes succinct and precise identification and treatment of real requirements separate from the descriptive prose in a document. TRACER permits the documentation of an engineering project's requirements and progress in a logical, controllable, traceable manner. TRACER's attributes include the presentation of current requirements and status from any linked computer terminal and the ability to differentiate headers and descriptive material from the requirements. Related requirements can be linked and traced. The program also enables portions of documents to be printed, individual approval and release of requirements, and the tracing of requirements down into the equipment specification. Requirement "links" can be made "pending" and invisible to others until the pending link is made "binding". Individuals affected by linked requirements can be notified of significant changes with acknowledgement of the changes required. An unlimited number of documents can be created for a project and an ASCII import feature permits existing documents to be incorporated

  20. Next Generation Microbiology Requirements

    Science.gov (United States)

    Ott, C. M.; Oubre, C. M.; Elliott, T. F.; Castro, V. A.; Pierson, D. L.

    2012-01-01

    As humans continue to explore deep into space, microorganisms will travel with them. The primary means to mitigate the risk of infectious disease are a combination of prudent spacecraft design and rigorous operational controls. The effectiveness of these methods are evaluated by microbiological monitoring of spacecraft, food, water, and the crew that is performed preflight, in-flight, and post-flight. Current NASA requirements associated with microbiological monitoring are based on culture-based methodology where microorganisms are grown on a semi-solid growth medium and enumerated. Subsequent identification of the organisms requires specialized labor and large equipment, which historically has been performed on Earth. Requirements that rely strictly on culture-based units limit the use of non-culture based monitoring technology. Specifically, the culture-based "measurement criteria" are Colony Forming Units (CFU, representing the growth of one microorganism at a single location on the agar medium) per a given volume, area, or sample size. As the CFU unit by definition is culture-based, these requirements limit alternative technologies for spaceflight applications. As spaceflight missions such as those to Mars extend further into space, culture-based technology will become difficult to implement due to the (a) limited shelf life of the culture media, (b) mass/volume necessary to carry these consumables, and (c) problems associated with the production of biohazardous material in the habitable volume of the spacecraft. In addition, an extensive amount of new knowledge has been obtained during the Space Shuttle, NASA-Mir, and International Space Station Programs, which gave direction for new or modified microbial control requirements for vehicle design and mission operations. The goal of this task is to develop and recommend a new set of requirements for vehicle design and mission operations, including microbiological monitoring, based upon "lessons learned" and new

  1. 9 CFR 3.104 - Space requirements.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Space requirements. 3.104 Section 3.104 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation...

  2. 40 CFR 264.91 - Required programs.

    Science.gov (United States)

    2010-07-01

    ....91 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Releases From Solid Waste Management Units § 264.91 Required programs. (a) Owners and operators subject to...

  3. 43 CFR 17.4 - Assurances required.

    Science.gov (United States)

    2010-10-01

    ... financial assistance to an institution of higher education (including assistance for construction, for... treatment of students. (2) The assurance required with respect to an institution of higher education, or any... encumber the real property as security for financing construction of new, or improvement of...

  4. Creativity, Requirements and Perspectives

    Directory of Open Access Journals (Sweden)

    Oliver Hoffmann

    2005-11-01

    Full Text Available Is there room for more creativity in information systems? This article grew out of an AWRE’04 panel discussion on creativity in requirements engineering, and the impact of requirements engineering on creativity in systems engineering and systems use. Both panel and article were motivated by the goal of identifying a framework for understanding creativity in a larger context and thus establishing a potential structure for future research. The authors’ research backgrounds differ widely and, at times, our views conflict – occasionally, quite sharply. We make underlying world views - our own and those of relevant disciplines – explicit; identify the paradox caused by the need to be functionally creative while leaving room for creativity in successive stages; and argue for a multi-paradigm framework for resolving this paradox.

  5. Entrepreneurial learning requires action

    DEFF Research Database (Denmark)

    Brink, Tove; Madsen, Svend Ole

    2014-01-01

    apply in industry. The findings of this study show that SME managers employ a practice-shaped holistic multi- and cross-disciplinary approach to learning. This learning approach is supported by theory dissemination, business challenge applications, and organisational prerequisites. Diversified learning......This paper reveals how managers of small- and medium-sized enterprises (SMEs) can utilise their participation in research-based training. Empirical research from a longitudinal study of 10 SMEs managers in the wind turbine industry is provided to describe a learning approach that SME managers can...... that is enhanced by essential large-scale industry players and other SME managers are required to create action and value in learning. An open-mindedness to new learning approaches by SME managers and an open-mindedness to multi- and cross-disciplinary collaboration with SME managers by facilitators is required....

  6. Human Systems Integration Requirements

    Science.gov (United States)

    2009-09-01

    Performance Parameter (NR-KPP) Products (aka Architectures )  Appendix B: References  Appendix C: Acronym List  Appendix D: Analysis methodology...Force Specialty Codes 36 HSI REQUIREMENTS GUIDE Universal Joint Task List Full Mission Trainers ( FMT ) Field Training Detachments On-the-Job...Occupational Health F3I Form-Fit-Function Interface FM Field Manual FMT Full Mission Trainers FOA Field Operating Agencies FOC Full Operational

  7. Reusable Security Requirements

    Science.gov (United States)

    2016-06-13

    2003 by Carnegie Mellon University page 1 Carnegie Mellon Software Engineering Institute Reusable Security Requirements RE’2003 RHAS’03 Workshop...PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Carnegie Mellon University , Software Engineering Institute,Pittsburgh,PA,15213 8. PERFORMING...Carnegie Mellon University page 2 Carnegie Mellon Software Engineering Institute In a Nut Shell • Similar Assets, Attackers, and Threats • Security

  8. Stylistic Requirement for Translation

    Institute of Scientific and Technical Information of China (English)

    HOU Yin-zhen

    2016-01-01

    Stylistic research is subordinate to language use research. The fast maturing modern stylistics has greatly boosted trans-lation studies. Translation has a close relationship with stylistics. Many problems can be solved in translation practice by stylis-tic theories and analysis methods. Based on a brief introduction of stylistics and the relationship between stylistics and transla-tion, this paper will give a specific analysis of the stylistic requirement for translation.

  9. Phi factory detector requirements

    Energy Technology Data Exchange (ETDEWEB)

    Arisaka, K.; Atac, M.; Berg, R.; Buchanan, C.; Calvette, M.; Khazin, B.; Kinoshita, K.; Muller, T.; Ohshima, T.; Olsen, S.; Park, J.; Santoni, C.; Shirai, J.; Solodov, E.; Thompson, J.; Triggiani, G.; Ueno, K.; Yamamoto, H.; Detector and Simulation Working Group

    1991-08-01

    We identify the experimental problems and the conditions required for successful phi-factory operation, and show the range of detector parameters which, in conjunction with different machine designs, may meet these conditions. We started by considering, comparing and criticizing the Italian and Novosibirsk designs. With this discussion as a background, we defined the apparent experimental problems and detector constraints. In this article we summarize our understanding. (orig./HSI).

  10. Shielding requirements in helical tomotherapy

    Science.gov (United States)

    Baechler, S.; Bochud, F. O.; Verellen, D.; Moeckli, R.

    2007-08-01

    Helical tomotherapy is a relatively new intensity-modulated radiation therapy (IMRT) treatment for which room shielding has to be reassessed for the following reasons. The beam-on-time needed to deliver a given target dose is increased and leads to a weekly workload of typically one order of magnitude higher than that for conventional radiation therapy. The special configuration of tomotherapy units does not allow the use of standard shielding calculation methods. A conventional linear accelerator must be shielded for primary, leakage and scatter photon radiations. For tomotherapy, primary radiation is no longer the main shielding issue since a beam stop is mounted on the gantry directly opposite the source. On the other hand, due to the longer irradiation time, the accelerator head leakage becomes a major concern. An analytical model based on geometric considerations has been developed to determine leakage radiation levels throughout the room for continuous gantry rotation. Compared to leakage radiation, scatter radiation is a minor contribution. Since tomotherapy units operate at a nominal energy of 6 MV, neutron production is negligible. This work proposes a synthetic and conservative model for calculating shielding requirements for the Hi-Art II TomoTherapy unit. Finally, the required concrete shielding thickness is given for different positions of interest.

  11. 社会资本在科技型中小企业成长过程中的作用机理研究%The Implication of Social Capital in Science-and-technology-based SMEs Growth

    Institute of Scientific and Technical Information of China (English)

    王林雪; 刘喜梅

    2011-01-01

    Social capital plays an important role in the growth of science - and - technology - based SMEs. This paper explores the role of social capital in science - and - technology - based SMEs growth. On the basis of our studies on social capital, entrepreneurial networks and science - and - technology - based SME growth, we develop a conceptual framework to describe their development through four phases: innovation assessment, product development, commercialization and rapid growth. We focus on discussing the key tasks of each phase and different types of networks relationships which are important in the transitional periods between the growth phases and help the firm to reach the rapid growth. Meanwhile we offer several managerial suggestions at the end of this paper.%社会资本在科技型中小企业成长过程中起着至关重要的作用.从社会资本、企业家网络和科技型中小企业成长出发,构建了一个基本框架模型,将科技型中小企业的成长划分为四个阶段,即创意形成阶段、产品开发阶段、商业化阶段以及达到快速成长阶段,着重分析了各个阶段的核心任务以及不同的网络关系促使企业从一个阶段发展到另一个阶段并最终达到快速企业成长,同时为企业管理者提供了可行性建议.

  12. LEGACY MANAGEMENT REQUIRES INFORMATION

    Energy Technology Data Exchange (ETDEWEB)

    CONNELL, C.W.; HILDEBRAND, R.D.

    2006-12-14

    ''Legacy Management Requires Information'' describes the goal(s) of the US Department of Energy's Office of Legacy Management (LM) relative to maintaining critical records and the way those goals are being addressed at Hanford. The paper discusses the current practices for document control, as well as the use of modern databases for both storing and accessing the data to support cleanup decisions. In addition to the information goals of LM, the Hanford Federal Facility Agreement and Consent Order, known as the ''Tri-Party Agreement'' (TPA) is one of the main drivers in documentation and data management. The TPA, which specifies discrete milestones for cleaning up the Hanford Site, is a legally binding agreement among the US Department of Energy (DOE), the Washington State Department of Ecology (Ecology), and the US Environmental Protection Agency (EPA). The TPA requires that DOE provide the lead regulatory agency with the results of analytical laboratory and non-laboratory tests/readings to help guide them in making decisions. The Agreement also calls for each signatory to preserve--for at least ten years after the Agreement has ended--all of the records in its or its contractors, possession related to sampling, analysis, investigations, and monitoring conducted. The tools used at Hanford to meet TPA requirements are also the tools that can satisfy the needs of LM.

  13. BER Science Network Requirements

    Energy Technology Data Exchange (ETDEWEB)

    Alapaty, Kiran; Allen, Ben; Bell, Greg; Benton, David; Brettin, Tom; Canon, Shane; Dart, Eli; Cotter, Steve; Crivelli, Silvia; Carlson, Rich; Dattoria, Vince; Desai, Narayan; Egan, Richard; Tierney, Brian; Goodwin, Ken; Gregurick, Susan; Hicks, Susan; Johnston, Bill; de Jong, Bert; Kleese van Dam, Kerstin; Livny, Miron; Markowitz, Victor; McGraw, Jim; McCord, Raymond; Oehmen, Chris; Regimbal, Kevin; Shipman, Galen; Strand, Gary; Flick, Jeff; Turnbull, Susan; Williams, Dean; Zurawski, Jason

    2010-11-01

    The Energy Sciences Network (ESnet) is the primary provider of network connectivity for the US Department of Energy Office of Science, the single largest supporter of basic research in the physical sciences in the United States. In support of the Office of Science programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet to be a highly successful enabler of scientific discovery for over 20 years. In April 2010 ESnet and the Office of Biological and Environmental Research, of the DOE Office of Science, organized a workshop to characterize the networking requirements of the science programs funded by BER. The requirements identified at the workshop are summarized and described in more detail in the case studies and the Findings section. A number of common themes emerged from the case studies and workshop discussions. One is that BER science, like many other disciplines, is becoming more and more distributed and collaborative in nature. Another common theme is that data set sizes are exploding. Climate Science in particular is on the verge of needing to manage exabytes of data, and Genomics is on the verge of a huge paradigm shift in the number of sites with sequencers and the amount of sequencer data being generated.

  14. 42 CFR 403.724 - Valid election requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Valid election requirements. 403.724 Section 403..., Conditions of Participation, and Payment § 403.724 Valid election requirements. (a) General requirements. An... CMS in writing. (2) The receipt of excepted medical treatment as defined in § 403.702 does not...

  15. Research on the Internet Finance and the Technology-based SMEs’ Financing%互联网金融与科技型中小企业融资研究

    Institute of Scientific and Technical Information of China (English)

    刘俊棋

    2014-01-01

    互联网金融的发展能适度解决科技型中小企业融资难的问题,而他们之间的对接障碍在于投资者和融资企业之间的信息不对称,通过建立科技型中小企业互联网金融的信息不对称模型分析其博弈均衡,并对互联网金融的四种融资模式比较分析后发现众筹融资模式是最适合科技型中小企业融资需要的,同时建议大胆尝试“网络联保融资+担保”的新型融资模式,最后从互联网金融自身运作、科技型中小企业征信体系建设、加强互联网金融监管、中介机构的引入以及投资者风险意识防范等五个角度提出优化策略。%With the development of Internet finance,the technology-based SMEs can solve their financing problem appropriate_ly.The abutting barrier between them is information asymmetry that exists between investors and financing enterprises.We estab_lish the information asymmetry model of the technology-based SMEs’ Internet financing to explore their game balance,and then we make a comparative analysis of the four kinds of financing patterns on Internet finance.It is found that the most suitable pat_tern for the financing need of the technology-based SMEs is crowd funding.Meanwhile,we recommend a new financing pattern of“network joint guarantee financing and warrant”.Finally,five optimization strategies are put forward:the Internet finance op_eration,the construction of credit system of the technology-based SMEs,strengthening the financial supervision,the introduc_tion of intermediaries and improving investors’ risk prevention consciousness.

  16. Hepatoma with cardiac metastasis: An advanced cancer requiring advanced treatment

    Institute of Scientific and Technical Information of China (English)

    Yu-Sheng Lin; Shih-Ming Jung; Feng-Chun Tsai; Chun-Nan Yeh; Tzu-Fang Shiu; Hsueh-Hua Wu; Pyng-Jing Lin; Pao-Hsien Chu

    2007-01-01

    AIM: To investigate the clinical and pathologic findings,and to discuss the pathophysiology of hepatocellular carcinoma with cardiac metastasis.METHODS: Eight hepatoma patients with cardiac metastasis, who were treated by surgical excision from 1993 to 2006, were retrospectively studied. Detailed clinical parameters were analyzed.RESULTS: Of those eight patients, two (25%) were women and six (75%) were men, with the mean age of 50 years (range, 40-70 years). The presentations included: asymptomatic (75%), heart failure (25%), and pulmonary embolism (12.5%). All lesions involved the right atrium, and extended to the lung (12.5%), inferior vena cava (25%), and left atrium (12.5%). The level of tumor marker, alpha-fetal protein, was not correlated with the severity of metastasis or disease prognosis.Moreover, the availably estimated doubling time was less than 3 mo. The pathological findings included variable hemorrhage and necrosis. The survival time following surgery also varied from one month to more than 30 mo.CONCLUSION: Hepatoma metastasis to the heart was detected in all eight patients. This study demonstrates that surgery might help the outcome in such cases.

  17. Symptoms of hyperprolactinemia with normal serum prolactin: is treatment required?

    Directory of Open Access Journals (Sweden)

    Deepti Verma

    2016-06-01

    Full Text Available Galactorrhea with menstrual abnormalities like oligomenorrhea or amenorrhea point towards a provisional diagnosis of increased serum prolactin levels or hyperprolactinemia. However, as the prolactin hormone is heterogeneous with two forms- the bioactive and the immunoactive forms, patients can have all the features of hyperprolactinemia with normal serum prolactin levels. [Int J Reprod Contracept Obstet Gynecol 2016; 5(6.000: 2041-2042

  18. Settlement Requires Milford, Mass. Glass Manufacturer to Improve Stormwater Treatment

    Science.gov (United States)

    Wastewater discharged by a glass manufacturing company in Milford, Mass. into wetlands adjacent to the Charles River will be cleaner as a result of a recent settlement between the manufacturer and the US Environmental Protection Agency.

  19. Requirements for ITER diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Young, K.M.

    1991-01-01

    The development and design of plasma diagnostics for the International Thermonuclear Experimental Reactor (ITER) present a formidable challenge for experimental plasma physicists. The large plasma size, the high central density and temperature and the very high thermal wall loadings provide new challenges for present measurement techniques and lead to a search for new methods. But the physics and control requirements for the long burn phase of the discharge, combined with very limited access to the plasma, constrained by the requirement for radiation shielding of the coils and sharing of access ports with heating and current drive power, remote manipulation, fueling and turn blanket modules, make for very difficult design choices. An initial attempt at these choices has been made by an international team of diagnostic physicists, gathering together in a series of three workshops during the ITER Conceptual Design Activity. This paper is based on that report and provides a summary of its most important points. To provide a background against which to place the diagnostic requirements and design concepts, the ITER device, its most important plasma properties and the proposed experimental program will be described. The specifications for the measurement of the plasma parameters and the proposed diagnostics for these measurements will then be addressed, followed by some examples of the design concepts that have been proposed. As a result of these design studies, it was clear that there were many uncertainties associated with these concepts, particularly because of the nuclear radiation environment, so that a Research and Development Program for diagnostic hardware was established. It will also be briefly summarized.

  20. NIRVANA network requirements

    Energy Technology Data Exchange (ETDEWEB)

    Wood, B.J.

    1990-08-01

    NIRVANA is an effort to standardize electrical computer-aided design workstations at Sandia National Laboratories in Albuquerque, New Mexico. The early effect of this project will be the introduction of at least 60 new engineering workstations at Sandia National Laboratories. Albuquerque, and at Allied Signal, Kansas City Division. These workstations are expected to begin arriving in September 1990. This paper proposes a design and outlines the requirements for a network to support the NIRVANA project. The author proposes a near-term network design, describes the security profile and caveats of this design, and proposes a long-term networking strategy for NIRVANA. 6 refs., 7 figs.

  1. BES Science Network Requirements

    Energy Technology Data Exchange (ETDEWEB)

    Biocca, Alan; Carlson, Rich; Chen, Jackie; Cotter, Steve; Tierney, Brian; Dattoria, Vince; Davenport, Jim; Gaenko, Alexander; Kent, Paul; Lamm, Monica; Miller, Stephen; Mundy, Chris; Ndousse, Thomas; Pederson, Mark; Perazzo, Amedeo; Popescu, Razvan; Rouson, Damian; Sekine, Yukiko; Sumpter, Bobby; Dart, Eli; Wang, Cai-Zhuang -Z; Whitelam, Steve; Zurawski, Jason

    2011-02-01

    The Energy Sciences Network (ESnet) is the primary provider of network connectivityfor the US Department of Energy Office of Science (SC), the single largest supporter of basic research in the physical sciences in the United States. In support of the Office ofScience programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet to be a highly successful enabler of scientific discovery for over 20 years.

  2. Development of scientific and technological bases for application of brown coal semi coke in the technology of non- milled silicon carbide

    Science.gov (United States)

    Anikin, A. E.; Galevsky, G. V.; Rudneva, V. V.; Nozdrin, E. V.; Galevsky, S. G.

    2016-09-01

    Thermodynamics is investigated, and the optimum temperature and time modes of carbonization of a briquetted silica fume batch- brown coal semi coke are defined. The complete carbonization of the batch in the conditions of heat treatment is achieved at a temperature of 1923 - 1973 K within 15 - 20 minutes. The conditions and indicators of the chemical enrichment of carbonization products are established. After enrichment, the carbide content is more than 90%. Silicon carbide micro-powder is obtained with a specific surface area 8000 - 9000 m2/kg.

  3. Repository seals requirements study

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-03

    The Yucca Mountain Site Characterization Project, managed by the Civilian Radioactive Waste Management System (CRWMS) Management and Operating Contractor (M and O) is conducting investigations to support the Viability Assessment and the License Application for a high-level nuclear waste repository at Yucca Mountain, Nevada. The sealing subsystem is part of the Yucca Mountain Waste Isolation System. The Yucca Mountain Site Characterization Project is currently evaluating the role of the sealing subsystem (shaft, ramp and exploratory borehole seals) in achieving the overall performance objectives for the Waste Isolation System. This report documents the results of those evaluations. This report presents the results of a repository sealing requirements study. Sealing is defined as the permanent closure of the shafts, ramps, and exploratory boreholes. Sealing includes those components that would reduce potential inflows above the repository, or that would divert flow near the repository horizon to allow vertical infiltration to below the repository. Sealing of such features as emplacement drifts was not done in this study because the current capability to calculate fracture flow into the drifts is not sufficiently mature. The objective of the study is to provide water or air flow performance based requirements for shafts, ramps, and exploratory boreholes located near the repository. Recommendations, as appropriate, are provided for developing plans, seals component testing, and other studies relating to sealing.

  4. Section 4: Requirements Intertwining

    Science.gov (United States)

    Loucopoulos, Pericles

    Business analysts are being asked to develop increasingly complex and varied business systems that need to cater to the changing and dynamic market conditions of the new economy. This is particularly acute in today’s turbulent business environment where powerful forces such as deregulation, globalisation, mergers, advances in information and telecommunications technologies, and increasing education of people provide opportunities for organising work in ways that have never before been possible. Enterprises attempt to create wealth either by getting better at improving their products and services or by harnessing creativity and human-centred management to create innovative solutions. In these business settings, requirements become critical in bridging system solutions to organisational and societal problems. They intertwine organisational, social, cognitive, and implementation considerations and they can provide unique insights to change in systems and their business context. Such design situations often involve multiple stakeholders from different participating organisations, subcontractors, divisions, etc., who may have a diversity of expertise, come from different organisational cultures and often have competing goals. The success or failure of many projects depends, to a large extent, on understanding the contextual setting of requirements and their interaction amongst a diverse population of stakeholders.

  5. The Effect of Using Mobile Technology-Based Methods That Record Food or Nutrient Intake on Diabetes Control and Nutrition Outcomes: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Judi Porter

    2016-12-01

    Full Text Available (1 Background: Mobile technologies may be utilised for dietary intake assessment for people with diabetes. The published literature was systematically reviewed to determine the effect of using mobile electronic devices to record food or nutrient intake on diabetes control and nutrition outcomes; (2 Methods: The review protocol was registered with PROSPERO: registration number CRD42016050079, and followed PRISMA guidelines. Original research of mobile electronic devices where food or nutrient intake was recorded in people with diabetes with any treatment regimen, and where this intervention was compared with usual care or alternative treatment models, was considered. Quality was assessed using the Quality Criteria Checklist for Primary Research; (3 Results: Nine papers formed the final library with a range of interventions and control practices investigated. The food/nutrient intake recording component of the intervention and patient engagement with the technology was not well described. When assessed for quality, three studies rated positive, five were neutral and one negative. There was significantly greater improvement in HbA1c in the intervention group compared to the control group in four of the nine studies; (4 Conclusion: Based on the available evidence there are no clear recommendations for using technology to record dietary data in this population.

  6. The Effect of Using Mobile Technology-Based Methods That Record Food or Nutrient Intake on Diabetes Control and Nutrition Outcomes: A Systematic Review.

    Science.gov (United States)

    Porter, Judi; Huggins, Catherine E; Truby, Helen; Collins, Jorja

    2016-12-17

    (1) Background: Mobile technologies may be utilised for dietary intake assessment for people with diabetes. The published literature was systematically reviewed to determine the effect of using mobile electronic devices to record food or nutrient intake on diabetes control and nutrition outcomes; (2) Methods: The review protocol was registered with PROSPERO: registration number CRD42016050079, and followed PRISMA guidelines. Original research of mobile electronic devices where food or nutrient intake was recorded in people with diabetes with any treatment regimen, and where this intervention was compared with usual care or alternative treatment models, was considered. Quality was assessed using the Quality Criteria Checklist for Primary Research; (3) Results: Nine papers formed the final library with a range of interventions and control practices investigated. The food/nutrient intake recording component of the intervention and patient engagement with the technology was not well described. When assessed for quality, three studies rated positive, five were neutral and one negative. There was significantly greater improvement in HbA1c in the intervention group compared to the control group in four of the nine studies; (4) Conclusion: Based on the available evidence there are no clear recommendations for using technology to record dietary data in this population.

  7. 演马庄矿矿井水害治理技术研究与实践%Research and Practice of Mine Flood Treatment Technology Based on Yanmazhuang Coal Mine

    Institute of Scientific and Technical Information of China (English)

    郭水涛

    2015-01-01

    The water level of the mine bottom aquifer of Yanmazhuang Coal Mine has always stayed at a high level, seriously threatening the safety production of the mine and affecting the economic development of the mine. By implementing "ladder-type reinforcement and deep river closure grouting technique", "deep and shallow hole alternate reinforcement technique" and "deep heavy curtain grouting reinforcement technique" and other techniques, the production conditions have been improved, which lays a foundation for the construction of high production high efficiency mine, thus the coal resources threatened by water disasters can be explored rationally and the resources recovery rate can be increased.%演马庄矿矿井底板含水层水位居高不下,严重威胁着矿井的安全生产,制约着矿井经济效益的提高。技术人员通过实施“梯进加固,深部截流注浆技术”、“深浅孔交替加固技术”以及“深部帷幕注浆加固技术”等水害治理技术,改善了生产条件,为建设高产高效矿井奠定了基础,使受水害威胁严重的煤炭资源得到合理开采,提高了资源回收率。

  8. 基于红外特性的自动垃圾分类综合处理技术%Comprehensive treatment automatic garbage classification technology based on infrared characteristic

    Institute of Scientific and Technical Information of China (English)

    陈璇; 方学梅; 李婷婷; 黄晓梅

    2014-01-01

    The paper is based on the automatic classification system of waste heat is the main use of the heat dissipation of different garbage distinguish main waste including food,plastic.And the use of metal detectors to detect metal,distinguish the glass using photosensitive sensor.Using the simulated robot will separate the rubbish into a designated area.%生活垃圾的分类和处理为当前社会迫切需要解决的问题,随之产生自动分类的概念。基于散热性的垃圾自动分类系统主要是利用了不同垃圾的散热性能不同区分主要垃圾包括食品类,纸类,塑料类。并利用金属探测仪来检测金属,利用光敏传感器区分玻璃。利用模拟机器手将分离的垃圾放入指定的区域。

  9. Safety simulation technology based on finite state machine%基于有限状态机的安全性仿真技术

    Institute of Scientific and Technical Information of China (English)

    王蓓; 赵廷弟; 焦健

    2011-01-01

    为了研究系统中事故的动态变化机理,探索事故发展过程中的运动行为,制定正确的应急控制措施,提出了基于有限状态机理论的安全性建模仿真方法.结合Simulink/Stateflow工具开发了面向事故机理与应急过程的建模仿真平台,实现了系统的机理模型、安全状态控制模型以及应急操作模型的有效融合.该平台能实现对人-机-环境综合系统进行动态仿真,为明确事故的动态变化过程和制定应急控制措施提供依据.通过对某舰船舱室事故过程的仿真实例,验证了该方法的有效性和合理性.%The safety modeling and simulation method based on finite state machine theory was proposed to research the dynamic change mechanism of the accident in system, as well as explore the movement during the accident evolution and establish exact emergency treatment. The modeling and simulation platform for accident mechanism and control process was developed in the environment of Simulink/Stateflow. The combination of system mechanism model, safety state control model and emergency treatment model can be achieved in this platform. Therefore the dynamic simulation for such systems that integrated with human-machine and environment can be implemented in an effective way. Then the simulation results can be obtained, which provide reference for the precise identification of the accident process and the establishment of exact control treatment. Finally the accident simulation example was given, which proved the validity and rationality of this proposed method.

  10. Current Treatments of Bruxism

    OpenAIRE

    Guaita, Marc; Högl, Birgit

    2016-01-01

    Opinion statement Despite numerous case reports, the evidence for treatment of bruxism is still low. Different treatment modalities (behavioral techniques, intraoral devices, medications, and contingent electrical stimulation) have been applied. A clinical evaluation is needed to differentiate between awake bruxism and sleep bruxism and rule out any medical disorder or medication that could be behind its appearance (secondary bruxism). A polysomnography is required only in a few cases of slee...

  11. Development of newly engineering technology based on computer analysis for dust diffusion; Funjin kakusan kaiseki gijutsu wo kihon to shita atarashii engineering gijutsu no tenkai

    Energy Technology Data Exchange (ETDEWEB)

    Ishii, K.; Murahashi, Y.; Kawakami, H.; Tanaka, K. [Nippon Steel Corp., Tokyo (Japan)

    1997-07-30

    Nippon Steel has made a comprehensive survey of the space environment designing technology that can precisely cope with the needs required for a space in a plant in a very wide range from the ventilation problem in steel mill to the turbulence problem in semiconductor plant, through accomplishing the development of computer analysis technology for dust diffusion that can estimate and control `air flow` and `dust movement` in an electric angstrom [furnace plant]. This paper describes the basic concept for establishing the computer analysis technology for dust diffusion and the concrete measures to solve accompanying problems, and further enters into details how the new engineering technology has innovated technical measures to solve problems, the new engineering technology which introduces a concept of both estimation and control to attain objects such as to curtail the equipment cost and so by estimating the `air flow` and `dust movement` to create both a new flow and movement depending on needs. 3 refs., 20 figs., 8 tabs.

  12. Knowing requires data

    Science.gov (United States)

    Naranjo, Ramon C.

    2017-01-01

    Groundwater-flow models are often calibrated using a limited number of observations relative to the unknown inputs required for the model. This is especially true for models that simulate groundwater surface-water interactions. In this case, subsurface temperature sensors can be an efficient means for collecting long-term data that capture the transient nature of physical processes such as seepage losses. Continuous and spatially dense network of diverse observation data can be used to improve knowledge of important physical drivers, conceptualize and calibrate variably saturated groundwater flow models. An example is presented for which the results of such analysis were used to help guide irrigation districts and water management decisions on costly upgrades to conveyance systems to improve water usage, farm productivity and restoration efforts to improve downstream water quality and ecosystems.

  13. Equipment Operational Requirements

    Energy Technology Data Exchange (ETDEWEB)

    Greenwalt, B; Henderer, B; Hibbard, W; Mercer, M

    2009-06-11

    The Iraq Department of Border Enforcement is rich in personnel, but poor in equipment. An effective border control system must include detection, discrimination, decision, tracking and interdiction, capture, identification, and disposition. An equipment solution that addresses only a part of this will not succeed, likewise equipment by itself is not the answer without considering the personnel and how they would employ the equipment. The solution should take advantage of the existing in-place system and address all of the critical functions. The solutions are envisioned as being implemented in a phased manner, where Solution 1 is followed by Solution 2 and eventually by Solution 3. This allows adequate time for training and gaining operational experience for successively more complex equipment. Detailed descriptions of the components follow the solution descriptions. Solution 1 - This solution is based on changes to CONOPs, and does not have a technology component. It consists of observers at the forts and annexes, forward patrols along the swamp edge, in depth patrols approximately 10 kilometers inland from the swamp, and checkpoints on major roads. Solution 2 - This solution adds a ground sensor array to the Solution 1 system. Solution 3 - This solution is based around installing a radar/video camera system on each fort. It employs the CONOPS from Solution 1, but uses minimal ground sensors deployed only in areas with poor radar/video camera coverage (such as canals and streams shielded by vegetation), or by roads covered by radar but outside the range of the radar associated cameras. This document provides broad operational requirements for major equipment components along with sufficient operational details to allow the technical community to identify potential hardware candidates. Continuing analysis will develop quantities required and more detailed tactics, techniques, and procedures.

  14. Analysis of Multi-Stakeholder Requirements Using Requirement Interaction Matrix

    Directory of Open Access Journals (Sweden)

    Rohayanti Hassan

    2017-09-01

    Full Text Available Software requirements engineering is an imperative phase in the software development life cycle in every project regardless of the project size. In a project, different people are involved in the requirements engineering process, including requirement engineers, stakeholders, end users, and system designers. Amongst them, stakeholders play an essential role. Differences in goals and priorities of multiple stakeholders would make requirements management complex and difficult, which is a huge challenge for requirement engineers. From time to time, new requirements emerge and existing requirements need changes to fulfil stakeholders’ goals. Thus, such situation leads to high requirements volatility and low stability which causes overlapping and conflicting of requirements. The correctness and validity of requirements are of paramount importance as they are the key factors toward a successful system. A deep understanding of requirement management technique that conforms to users’ needs is crucial. Such technique of the concept is applied to the Labour Management System. In this study, we have discussed the implementation of analysis of multi-stakeholder requirements using requirement interaction matrix in the f. The study used real requirements to yield a solid and dependable result. We have documented the requirements using a template and assessed their respective volatility level. An algorithm is constructed to   show   that   the   technique has managed to minimize   the time   used   when   checking requirements.

  15. 基于PMOS三维选通高速门控技术%3D Range-Gated High Speed Gate-Control Technology Based on PMOS

    Institute of Scientific and Technical Information of China (English)

    杨金宝; 周燕; 范松涛; 曾华林; 王新伟

    2012-01-01

    为三维选通成像提供了纳秒级阴极选通高速门控开关的设计与实现.该门控开关创新性地采用互补级联开关的方式实现阴极正负电压的高速选通.结合功率开关管的特性,使用功率PMOS作为前级开关,产生平项质量好的正脉冲;采用功率三极管作为后级开关,无需额外驱动,通过二者互补级联的方式产生阴极选通负脉冲.实验表明,最终开关的上升沿时间为13.4 ns,下降沿时间为24.6ns,最小脉宽为50 ns,最高工作频率100 kHz,导通电压-200 V,关断电压40V,满足三维选通门控要求.门控开关通过互补级联方式,不但寄生参数小,脉冲上升、下降时间小,脉冲平顶质量好,时序控制精度高,无需隔离驱动,而且通过功率三极管作后级开关,可以获得比TTL触发脉冲更窄的脉宽,具有良好的脉宽特性.%Design and implementation of nanosecond high speed gate-control switch was required for 3D range-gated imaging. Complementary cascade was used to implement the high speed switch with negative and positive voltage. Power PMOS and power triode transistor were used according to the switch prosperities. Power PMOS was the front switch which produced a positive pulse with good flat-roofed quality, and power triode transistor was the rear one which didnt require extra driver. Through the complementary cascade of the two switches, cathode negative pulse was obtained. Experiments showed that the rising time and the falling time of the gate-control switch were 13.4 ns and 24.6 ns respectively. The narrowest pulse width was 50 ns and the highest frequency was as high as 100 kHz. The turn-on voltage of the switch was -200 V and the turn-off voltage was 40 V. All of these met the requirements of 3D range-gated imaging. Through complementary cascade switch, the rising and falling time of the pulse are small, and good flat-roofed quality is obtained. In addition, the switch has many advantages such as simple structure

  16. A Simplified Procedure for Safety Requirements Derivation

    Directory of Open Access Journals (Sweden)

    Eugen Ioan Gergely

    2008-05-01

    Full Text Available The paper develops a procedure for analysis of PLC-controlled system risk due to component failure and for derivation of safety integrity requirements for components, focusing on software requirements. The approach allows fully integrated treatment of random and systematic failure. It can be applied at different levels of design detail and at different stages of the system development lifecycle. The procedure does not address how to assess failure rates, but provides a foundation for integrating PLC software assessment into system riskassessment and for making trade-offs in design.

  17. ASCR Science Network Requirements

    Energy Technology Data Exchange (ETDEWEB)

    Dart, Eli; Tierney, Brian

    2009-08-24

    The Energy Sciences Network (ESnet) is the primary provider of network connectivity for the US Department of Energy Office of Science, the single largest supporter of basic research in the physical sciences in the United States. In support of the Office of Science programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet to be a highly successful enabler of scientific discovery for over 20 years. In April 2009 ESnet and the Office of Advanced Scientific Computing Research (ASCR), of the DOE Office of Science, organized a workshop to characterize the networking requirements of the programs funded by ASCR. The ASCR facilities anticipate significant increases in wide area bandwidth utilization, driven largely by the increased capabilities of computational resources and the wide scope of collaboration that is a hallmark of modern science. Many scientists move data sets between facilities for analysis, and in some cases (for example the Earth System Grid and the Open Science Grid), data distribution is an essential component of the use of ASCR facilities by scientists. Due to the projected growth in wide area data transfer needs, the ASCR supercomputer centers all expect to deploy and use 100 Gigabit per second networking technology for wide area connectivity as soon as that deployment is financially feasible. In addition to the network connectivity that ESnet provides, the ESnet Collaboration Services (ECS) are critical to several science communities. ESnet identity and trust services, such as the DOEGrids certificate authority, are widely used both by the supercomputer centers and by collaborations such as Open Science Grid (OSG) and the Earth System Grid (ESG). Ease of use is a key determinant of the scientific utility of network-based services. Therefore, a key enabling aspect for scientists beneficial use of high

  18. 基于流程模拟的化工故障检测技术%Chemical process fault detection technology based on process simulation

    Institute of Scientific and Technical Information of China (English)

    李秀喜; 袁延江

    2014-01-01

    提出了一种使用MATLAB仿真工具箱Simulink与动态模拟软件Aspen Dynamics相互调用来实现化工过程监测的方法。该方法具有以下优点:Aspen Dynamics能够快速建立精确的动态模型,具有完善的物性数据库,同时可以方便根据实际的化工过程对模型进行调整;使用Simulink仿真工具箱可以实时采集数据作为模型输入,同时完成对数据的必要处理。为了检测方法的可行性,将其应用于一个虚拟精馏过程来检验监测效果,结果表明,其可以实现对存在生产计划变更过程的故障监测和无生产计划变更过程中故障的监测。%A chemical process monitoring method using Simulink Toolbox of MATLAB to invoke Aspen Dynamics to dynamically simulate the chemical process was proposed. In most of the previous literatures about model-based fault detection, the mechanistic model should be built by hand,which is very time-consuming and requires the user to have a high professional quality. Using this method can build dynamics simulation for chemical in a quick and accurate way using Aspen Dynamics even the people who don’t have high professional quality in chemical engineering, meanwhile, the data collected from the factory often require correction, using Simulink Toolbox can conveniently correct the model data and measured data, at the same time the real-time factory data was collected as input data for dynamics simulation in order to achieve real-time process monitoring. The method was tested using a virtual distillation process in Aspen Dynamics, the results show that it can detect faults in chemical process with and without production change. Because the fault data also comes from a distillation process using Aspen Dynamics, the simulate data and the measured data without process fault are very similar, the method to correct the simulation data was not include.

  19. Dephi中基于ADO技术实现定制报表的生成%ADO technology based automatic generation of customized report forms in Dephi

    Institute of Scientific and Technical Information of China (English)

    丁风海; 夏伟; 邱斌; 王琳娜

    2012-01-01

    ADO (active data objects) is OLE DB technology developed by Microsoft Corporation. It is based on the data access rules and API access, and provides a consistent, high-performance and high compatibility data access interface. The application of ADO technological development application program allows the program developers to control database access easily, thus can produce database access procedures which meet client requirements. The access mechanism and method of the databases which use ADO technology in Dephi is introduced emphatically. Through a simple example, the highly specialized customized report forms automatically generated by combining OLE Automation technology are described in detail.%ADO是Microsoft发展的OLE DB技术,它基于COM数据访问规则和API访问,并提供一个一致、高性能、高兼容性的数据访问接口.使用ADO技术开发应用程序可以使程序开发者更容易地控制对数据库的访问,从而产生符合用户需求的数据库访问程序.着重介绍了在Dephi中应用ADO技术的数据库的访问机制和实现方法,并通过简单实例详述结合OLE自动化技术自动生成专业性较强的定制报表.

  20. 基于防腐考虑的TPO防水施工技术%TPO Waterproof Construction Technology Based on the Anti-corrosion

    Institute of Scientific and Technical Information of China (English)

    颜斌; 江涛; 汪绍元; 吴卓; 张爽

    2015-01-01

    在地下防水施工过程中,由于土壤被污染,普通防水材料容易被有机物腐蚀溶解,无法满足直接接触二氯乙烷等环境的防水要求。结合北京某住宅项目工程实例,探索TPO防水材料在特殊环境中的应用,并总结出了其技术特点及应用要点,介绍了TPO防水卷材具体施工工艺流程及关键节点做法,取得良好的经济和环保效益。%During the construction of the underground waterproof engineering, it is found that ordinary building waterproof materials can be corroded easily, the construction can’ t meet the requirements for the direct contact with the dichloromethane( CH2 Cl2 ) because of the soil contamination. Combining with the engineering example of some residential buildings in Beijing, this paper explores the TPO system application in the particular environment, and summarizes the characteristics for the technical and the application of the TPO system. Moreover, it introduces the construction process and key joints structure of TPO system, then good economic and environmental benefits are achieved.