Robotics in rehabilitation: technology as destiny.

Science.gov (United States)

Stein, Joel

2012-11-01

Robotic aids for rehabilitation hold considerable promise but have not yet achieved widespread clinical adoption. Barriers to adoption include the limited data on efficacy, the single-purpose design of existing robots, financial considerations, and clinician lack of familiarity with this technology. Although the path forward to clinical adoption may be slow and have several false starts, the labor-saving aspect of robotic technology will ultimately ensure its adoption.

The Promises of Biology and the Biology of Promises

DEFF Research Database (Denmark)

Lee, Jieun

2015-01-01

commitments with differently imagined futures. I argue that promises are constitutive of the stem cell biology, rather than being derivative of it. Since the biological concept of stem cells is predicated on the future that they promise, the biological life of stem cells is inextricably intertwined...... patients’ bodies in anticipation of materializing the promises of stem cell biology, they are produced as a new form of biovaluable. The promises of biology move beyond the closed circuit of scientific knowledge production, and proliferate in the speculative marketplaces of promises. Part II looks at how...... of technologized biology and biological time can appear promising with the backdrop of the imagined intransigence of social, political, and economic order in the Korean society....

Magnetic Refrigeration – an Energy Efficient Technology for the Future

DEFF Research Database (Denmark)

Bahl, Christian Robert Haffenden; Smith, Anders; Pryds, Nini

2009-01-01

. This magnetocaloric effect is inherent to all magnetic materials, but manifests itself stronger in some materials. The thermodynamically reversible nature of the magnetocaloric effect holds out the promise of a more energy efficient method of refrigeration compared to conventional compressor technology. Coupling...

A Pedagogical Framework for Technology Integration in ESL Classrooms: The Promises and Challenges of Integration

Science.gov (United States)

Yang, Sha; Walker, Victoria

2015-01-01

Technologies have the potential to support language teaching and learning, but English as a Second Language (ESL) teachers in the United States (U.S.) either sparingly use technologies for instruction or use them at low level. Although previous research has indicated some promises and challenges faced by U.S. ESL teachers with integrating…

Amyloid Beta and Tau as Alzheimer's Disease Blood Biomarkers: Promise From New Technologies.

Science.gov (United States)

Lue, Lih-Fen; Guerra, Andre; Walker, Douglas G

2017-07-01

The utility of the levels of amyloid beta (Aβ) peptide and tau in blood for diagnosis, drug development, and assessment of clinical trials for Alzheimer's disease (AD) has not been established. The lack of availability of ultra-sensitive assays is one critical issue that has impeded progress. The levels of Aβ species and tau in plasma and serum are much lower than levels in cerebrospinal fluid. Furthermore, plasma or serum contain high levels of assay-interfering factors, resulting in difficulties in the commonly used singulex or multiplex ELISA platforms. In this review, we focus on two modern immune-complex-based technologies that show promise to advance this field. These innovative technologies are immunomagnetic reduction technology and single molecule array technology. We describe the technologies and discuss the published studies using these technologies. Currently, the potential of utilizing these technologies to advance Aβ and tau as blood-based biomarkers for AD requires further validation using already collected large sets of samples, as well as new cohorts and population-based longitudinal studies.

Blocking TRPA1 in Respiratory Disorders: Does It Hold a Promise?

Directory of Open Access Journals (Sweden)

Indranil Mukhopadhyay

2016-11-01

Full Text Available Transient Receptor Potential Ankyrin 1 (TRPA1 ion channel is expressed abundantly on the C fibers that innervate almost entire respiratory tract starting from oral cavity and oropharynx, conducting airways in the trachea, bronchi, terminal bronchioles, respiratory bronchioles and upto alveolar ducts and alveoli. Functional presence of TRPA1 on non-neuronal cells got recognized recently. TRPA1 plays a well-recognized role of “chemosensor”, detecting presence of exogenous irritants and endogenous pro-inflammatory mediators that are implicated in airway inflammation and sensory symptoms like chronic cough, asthma, chronic obstructive pulmonary disease (COPD, allergic rhinitis and cystic fibrosis. TRPA1 can remain activated chronically due to elevated levels and continued presence of such endogenous ligands and pro-inflammatory mediators. Several selective TRPA1 antagonists have been tested in animal models of respiratory disease and their performance is very promising. Although there is no TRPA1 antagonist in advanced clinical trials or approved on market yet to treat respiratory diseases, however, limited but promising evidences available so far indicate likelihood that targeting TRPA1 may present a new therapy in treatment of respiratory diseases in near future. This review will focus on in vitro, animal and human evidences that strengthen the proposed role of TRPA1 in modulation of specific airway sensory responses and also on preclinical and clinical progress of selected TRPA1 antagonists.

Flotation: A promising microalgae harvesting and dewatering technology for biofuels production.

Science.gov (United States)

Ndikubwimana, Theoneste; Chang, Jingyu; Xiao, Zongyuan; Shao, Wenyao; Zeng, Xianhai; Ng, I-Son; Lu, Yinghua

2016-03-01

Microalgal biomass as renewable energy source is believed to be of great potential for reliable and sustainable biofuels production. However, microalgal biomass production is pinned by harvesting and dewatering stage thus hindering the developing and growing microalgae biotechnology industries. Flotation technology applied in mineral industry could be potentially applied in microalgae harvesting and dewatering, however substantial knowledge on different flotation units is essential. This paper presents an overview on different flotation units as promising cost-effective technologies for microalgae harvesting thus bestowing for further research in development and commercialization of microalgae based biofuels. Dispersed air flotation was found to be less energy consuming. Moreover, Jameson cell flotation and dispersed ozone flotation are believed to be energy efficient microalgae flotation approaches. Microalgae harvesting and dewatering by flotation is still at embryonic stage, therefore extended studies with the focus on life cycle assessment, sustainability of the flotation unit, optimization of the operating parameters using different algal species is imperative. Though there are a number of challenges in microalgae harvesting and dewatering, with well designed and developed cultivation, harvesting/dewatering, extraction and conversion technologies, progressively, microalgae technology will be of great potential for biological carbon sequestration, biofuels and biochemicals production. Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Holding Pressure and Its Influence on Quality in PIM Technology

Directory of Open Access Journals (Sweden)

Pavel Petera

2012-01-01

Full Text Available The PIM (powder injection molding process consists of several steps in which faults can occur. The quality of the part that is produced usually cannot be seen until the end of the process. It is therefore necessary to find a way to discover the fault earlier in the process. The cause of defects is very often “phase separation” (inhomogeneity in powder distribution, which can also be influenced by the holding pressure. This paper evaluates the powder distribution with a new method based on density measurement. Measurements were made using various holding pressure values.

Technological advances in renal replacement therapy: five years and beyond.

Science.gov (United States)

Rastogi, Anjay; Nissenson, Allen R

2009-12-01

The worldwide epidemic of chronic kidney disease shows no signs of abating in the near future. Current dialysis forms of renal replacement therapy (RRT), even though successful in sustaining life and improving quality of life somewhat for patients with ESRD, have many limitations that result in still unacceptably high morbidity and mortality. Transplantation is an excellent option but is limited by the scarcity of organs. An ideal form of RRT would mimic the functions of natural kidneys and be transparent to the patient, as well as affordable to society. Recent advances in technology, although generally in early stages of development, might achieve these goals. The application of nanotechnology, microfluidics, bioreactors with kidney cells, and miniaturized sorbent systems to regenerate dialysate makes clinical reality seem closer than ever before. Finally, stem cells hold much promise, both for kidney disease and as a source of tissues and organs. In summary, nephrology is at an exciting crossroad with the application of innovative and novel technologies to RRT that hold considerable promise for the near future.

Promising Practices in Higher Education: Art Education and Human Rights Using Information, Communication Technologies (ICT)

Science.gov (United States)

Black, Joanna; Cap, Orest

2014-01-01

Promising pedagogical practices is described in relation to incorporating ICT (Information, Communication and Technologies) with the study of Human Rights issues in Visual Arts Education for teacher candidates. As part of a course, "Senior Years Art," students at the Faculty of Education, University of Manitoba during 2013-2014…

De Novo Human Cardiac Myocytes for Medical Research: Promises and Challenges

Directory of Open Access Journals (Sweden)

Veronique Hamel

2017-01-01

Full Text Available The advent of cellular reprogramming technology has revolutionized biomedical research. De novo human cardiac myocytes can now be obtained from direct reprogramming of somatic cells (such as fibroblasts, from induced pluripotent stem cells (iPSCs, which are reprogrammed from somatic cells, and from human embryonic stem cells (hESCs. Such de novo human cardiac myocytes hold great promise for in vitro disease modeling and drug screening and in vivo cell therapy of heart disease. Here, we review the technique advancements for generating de novo human cardiac myocytes. We also discuss several challenges for the use of such cells in research and regenerative medicine, such as the immature phenotype and heterogeneity of de novo cardiac myocytes obtained with existing protocols. We focus on the recent advancements in addressing such challenges.

Low-temperature deposition manufacturing: A novel and promising rapid prototyping technology for the fabrication of tissue-engineered scaffold.

Science.gov (United States)

Liu, Wei; Wang, Daming; Huang, Jianghong; Wei, You; Xiong, Jianyi; Zhu, Weimin; Duan, Li; Chen, Jielin; Sun, Rong; Wang, Daping

2017-01-01

Developed in recent years, low-temperature deposition manufacturing (LDM) represents one of the most promising rapid prototyping technologies. It is not only based on rapid deposition manufacturing process but also combined with phase separation process. Besides the controlled macropore size, tissue-engineered scaffold fabricated by LDM has inter-connected micropores in the deposited lines. More importantly, it is a green manufacturing process that involves non-heating liquefying of materials. It has been employed to fabricate tissue-engineered scaffolds for bone, cartilage, blood vessel and nerve tissue regenerations. It is a promising technology in the fabrication of tissue-engineered scaffold similar to ideal scaffold and the design of complex organs. In the current paper, this novel LDM technology is introduced, and its control parameters, biomedical applications and challenges are included and discussed as well. Copyright © 2016 Elsevier B.V. All rights reserved.

Intelligent computer aided training systems in the real world: Making the technology accessible to the educational mainstream

Science.gov (United States)

Kovarik, Madeline

1993-01-01

Intelligent computer aided training systems hold great promise for the application of this technology to mainstream education and training. Yet, this technology, which holds such a vast potential impact for the future of education and training, has had little impact beyond the enclaves of government research labs. This is largely due to the inaccessibility of the technology to those individuals in whose hands it can have the greatest impact, teachers and educators. Simply throwing technology at an educator and expecting them to use it as an effective tool is not the answer. This paper provides a background into the use of technology as a training tool. MindLink, developed by HyperTech Systems, provides trainers with a powerful rule-based tool that can be integrated directly into a Windows application. By embedding expert systems technology it becomes more accessible and easier to master.

KSC Education Technology Research and Development Plan

Science.gov (United States)

Odell, Michael R. L.

2003-01-01

Educational technology is facilitating new approaches to teaching and learning science, technology, engineering, and mathematics (STEM) education. Cognitive research is beginning to inform educators about how students learn providing a basis for design of more effective learning environments incorporating technology. At the same time, access to computers, the Internet and other technology tools are becoming common features in K-20 classrooms. Encouraged by these developments, STEM educators are transforming traditional STEM education into active learning environments that hold the promise of enhancing learning. This document illustrates the use of technology in STEM education today, identifies possible areas of development, links this development to the NASA Strategic Plan, and makes recommendations for the Kennedy Space Center (KSC) Education Office for consideration in the research, development, and design of new educational technologies and applications.

Aerospace Technology Innovation. Volume 10

Science.gov (United States)

Turner, Janelle (Editor); Cousins, Liz (Editor); Bennett, Evonne (Editor); Vendette, Joel (Editor); West, Kenyon (Editor)

2002-01-01

Whether finding new applications for existing NASA technologies or developing unique marketing strategies to demonstrate them, NASA's offices are committed to identifying unique partnering opportunities. Through their efforts NASA leverages resources through joint research and development, and gains new insight into the core areas relevant to all NASA field centers. One of the most satisfying aspects of my job comes when I learn of a mission-driven technology that can be spun-off to touch the lives of everyday people. NASA's New Partnerships in Medical Diagnostic Imaging is one such initiative. Not only does it promise to provide greater dividends for the country's investment in aerospace research, but also to enhance the American quality of life. This issue of Innovation highlights the new NASA-sponsored initiative in medical imaging. Early in 2001, NASA announced the launch of the New Partnerships in Medical Diagnostic Imaging initiative to promote the partnership and commercialization of NASA technologies in the medical imaging industry. NASA and the medical imaging industry share a number of crosscutting technologies in areas such as high-performance detectors and image-processing tools. Many of the opportunities for joint development and technology transfer to the medical imaging market also hold the promise for future spin back to NASA.

Implications of advanced vehicle technologies for older drivers.

Science.gov (United States)

Molnar, Lisa J; Eby, David W

2017-09-01

Advances are being made in vehicle technologies that may help older adults compensate for some of the declines in abilities associated with aging. These advances hold promise for increasing vehicle safety, reducing injuries, and making the driving task more comfortable. However, important research gaps remain with regard to how various advanced technologies impact the safety of older drivers, as well as older drivers' perceptions about these technologies. This special issue contains seven original contributions that address these issues. Specific topics include the: congruence of design guidelines with the needs and abilities of older drivers, transfer of control between automated and manual driving, use of in-vehicle monitoring technology, motivations for technology use and assigned meanings, technology valuation, and effects on driving behavior. Copyright © 2017 Elsevier Ltd. All rights reserved.

A contribution to the identification of promising technologies for SwissEnergy R and D policy in 2050

Energy Technology Data Exchange (ETDEWEB)

Buerer, M. [E4tech Switzerland, Lausanne (Switzerland); Cremer, C. [Swiss Federal Institute of Technology (ETH), Centre for Energy Policy and Economics (CEPE), Zuerich (Switzerland)

2006-07-01

This comprehensive final report for the Swiss Federal Office of Energy (SFOE) takes a look at the conclusions of a study-project on promising energy technologies that could make a contribution to Swiss energy supply in the future. A review of literature on the subject is presented and the methodology used for the identification of the promising technologies is described. Four future possibilities of combining low or high levels of decentralisation of power generation with a low or high degree of fossil fuel utilisation are presented and discussed. The opinions for industry and the Swiss economy on the subject are looked at, as is research currently being carried out. Also, the so-called '2000-Watt Society' is briefly looked at. European aspects are discussed. Finally, exemplary prioritisation for the four options mentioned above along with the case of nothing being done at all are discussed.

A Numerical and Graphical Review of Energy Storage Technologies

Directory of Open Access Journals (Sweden)

Siraj Sabihuddin

2014-12-01

Full Text Available More effective energy production requires a greater penetration of storage technologies. This paper takes a looks at and compares the landscape of energy storage devices. Solutions across four categories of storage, namely: mechanical, chemical, electromagnetic and thermal storage are compared on the basis of energy/power density, specific energy/power, efficiency, lifespan, cycle life, self-discharge rates, capital energy/power costs, scale, application, technical maturity as well as environmental impact. It’s noted that virtually every storage technology is seeing improvements. This paper provides an overview of some of the problems with existing storage systems and identifies some key technologies that hold promise.

Photonic crystals: emerging biosensors and their promise for point-of-care applications.

Science.gov (United States)

Inan, Hakan; Poyraz, Muhammet; Inci, Fatih; Lifson, Mark A; Baday, Murat; Cunningham, Brian T; Demirci, Utkan

2017-01-23

Biosensors are extensively employed for diagnosing a broad array of diseases and disorders in clinical settings worldwide. The implementation of biosensors at the point-of-care (POC), such as at primary clinics or the bedside, faces impediments because they may require highly trained personnel, have long assay times, large sizes, and high instrumental cost. Thus, there exists a need to develop inexpensive, reliable, user-friendly, and compact biosensing systems at the POC. Biosensors incorporated with photonic crystal (PC) structures hold promise to address many of the aforementioned challenges facing the development of new POC diagnostics. Currently, PC-based biosensors have been employed for detecting a variety of biotargets, such as cells, pathogens, proteins, antibodies, and nucleic acids, with high efficiency and selectivity. In this review, we provide a broad overview of PCs by explaining their structures, fabrication techniques, and sensing principles. Furthermore, we discuss recent applications of PC-based biosensors incorporated with emerging technologies, including telemedicine, flexible and wearable sensing, smart materials and metamaterials. Finally, we discuss current challenges associated with existing biosensors, and provide an outlook for PC-based biosensors and their promise at the POC.

Modeling energy technology choices. Which investment analysis tools are appropriate?

International Nuclear Information System (INIS)

Johnson, B.E.

1994-01-01

A variety of tools from modern investment theory appear to hold promise for unraveling observed energy technology investment behavior that often appears anomalous when analyzed using traditional investment analysis methods. This paper reviews the assumptions and important insights of the investment theories most commonly suggested as candidates for explaining the apparent ''energy technology investment paradox''. The applicability of each theory is considered in the light of important aspects of energy technology investment problems, such as sunk costs, uncertainty and imperfect information. The theories addressed include the capital asset pricing model, the arbitrage pricing theory, and the theory of irreversible investment. Enhanced net present value methods are also considered. (author)

Social Relations and Technology: Continuity, Context, and Change.

Science.gov (United States)

Antonucci, Toni C; Ajrouch, Kristine J; Manalel, Jasmine A

2017-11-01

Social relations, although basic to human nature, health and well-being, have become increasingly complicated as a result of changing population demography and technology. In this essay, we provide a historical overview of social relations, especially as they affect older people. We briefly review the evolution of theory and measurement surrounding social relations as well as early empirical evidence. We consider how social relations have changed over time as well as continuity and change regarding basic characteristics of social relations. Of special interest is the emerging influence of technology on how people maintain contact, especially the changing ways people can use technology to increase, decrease, maintain, or avoid social relations. We consider both negative and positive aspects of these new technologies and their influence on health and well-being. Finally, we conclude that new and emerging technologies hold great promise for the future by overcoming traditional barriers to maintaining social contact, support exchange, and information acquisition. Nevertheless, we caution that these new technologies can have the dehumanizing effect of distance thus creating the potential for insensitivity and increased negativity. In sum, we are cautiously optimistic about the promise of technology to expand, but not replace, traditional forms of social contact.

INNOVATION DEVELOPMENT MANAGEMENT IN VERTICALLY INTEGRATED HOLDING COMPANY

Directory of Open Access Journals (Sweden)

Natalya T. Uspenskaja

2015-01-01

Full Text Available The trend towards production consolidation and integration processes taking place both in the Russian and global economies leads to development of business associations, with a holding company being the most common form inRussiaand around the globe. The evidence in favor of the formation of holding companies is that they can benefit from the scale (bulk purchasing, centralized stuff training; in the global capital and exports markets they can be more effective than smaller businesses and, if non-profitable, a loss-making structure is easier to liquidate than the entire company; holding companies and associations can be an effective defender from political interference. As the importance of the well-functioning and harmonized procedure for the companies’ integration will increase (especially in the context of Russian business, where specific features of many areas of the production system imply the use of holding oligopolies as the most effective form of market structures, there is a need in their more profound study and, in particular, in the analysis of the most important technologies of the general integration procedure. The article outlines the relevance of innovative development management of vertically integrated holding systems, lists principles of innovative activity management and considers the features of innovation management of a vertically integrated holding company. The objective of the research is to study theoretical and practical aspects of innovative development management in vertically integrated holding systems. The object of research is management structures in innovative holding companies. While working on the article, the following methods of economic research were used: abstract and logical method, empirical method, method of expert evaluations, as well as methods of structural and functional and statistical analysis. 

Role of a national research organization in the transfer of nuclear technology

International Nuclear Information System (INIS)

Ahmad, Ishaq

1977-01-01

Nuclear technology holds great promise for developing countries because it can contribute to national development. The developing countries, however, lack the resources and expertise to develop nuclear technology through their own efforts. A national research organization devoted to the promotion and utilization of nucler technology can provide an effective channel for the transfer of nuclear technology. The problems which the national research organization is likely to face in executing its tasks as an agent for the transfer of technology are discussed. An appreciation of these problems would enable the organization to restructure its priorities so as to achieve maximum effectiveness. The various ways by which the national research organization can speed up the task of transfer of technology are also discussed

Promising Practices in Citywide Afterschool Initiatives. CityWorks: Focus on Infrastructure.

Science.gov (United States)

Hall, Georgia

This brief is the first in a series featuring promising practices in city-wide after-school initiatives, with a focus at the infrastructure level, focusing on the infrastructure representing the underlying elements or framework that hold a system or initiative together. The brief identifies practices to support the public relations function and…

The promises of educational technology: a reassessment

NARCIS (Netherlands)

Ely, Donald P.; Plomp, T.

1986-01-01

The claims made for educational technology have not always been realized. Many programmes in education based on media and technology have produced useful documentation and supportive research; others have failed. The current, comprehensive definition of educational technology is a helpful key to

Transportation and information trends in technology and policy

CERN Document Server

Piyushimita

2013-01-01

Transformations in wireless connectivity and location-aware technologies hold the promise of bringing a sea-change in the way transportation information is generated and used in the future. Sensors in the transportation system, when integrated with those in other sectors (for example, energy, utility and health) have the potential to foster novel new ways of improving livability and sustainability.The end-result of these developments has been somewhat contradictory. Although automation in the transportation environment has become increasingly widespread, the level of involvement and active par

Technology's Potential, Promise for Enhancing Student Learning

Science.gov (United States)

Golden, Michael

2004-01-01

Technology is a tool that has the potential to empower educational leaders at all levels--whether they are superintendents, principals, teachers, board members or state officials--as well as to redefine what education means in the 21st century. Technology provides more accurate information and advanced communication capabilities. Technology can be…

Cogeneration applications of biomass gasifier/gas turbine technologies in the cane sugar and alcohol industries

International Nuclear Information System (INIS)

Ogden, J.M.; Williams, R.H.; Fulmer, M.E.

1994-01-01

Biomass integrated gasifier/gas turbine (BIG/GT) technologies for cogeneration or stand-alone power applications hold forth the promise of being able to produce electricity at lower cost in many instances than most alternatives, including large central-station, coal-fired, steam-electric power plants with fuel gas desulphurization, nuclear power plants, and hydroelectricity power plants. BIG/GT technologies offer environmental benefits as well, including the potential for zero net carbon dioxide emissions, if the biomass feedstock is grown renewably. (author). 77 refs., 9 figs., 16 tabs

Resourcefulness training intervention: a promising approach to improve mental health of mothers with technology-dependent children.

Science.gov (United States)

Toly, Valerie Boebel; Musil, Carol M; Zauszniewski, Jaclene A

2014-02-01

The population of children dependent on medical technology such as mechanical ventilation, feeding tubes, and supplemental oxygen continues to grow in the United States. These children are frequently cared for by their mothers at home following hospital discharge. Research indicates that these mothers are at high risk for negative mental health outcomes that affect both caregiver and care recipient. The purpose of this randomized controlled pilot trial was to determine the feasibility, acceptability, and efficacy of resourcefulness training (RT), a cognitive-behavioral intervention, among mothers of technology-dependent children. RT was found to be a feasible and acceptable intervention with this population during the 6 week study. The effect size in this pilot study demonstrates initial efficacy and indicates areas for strengthening the intervention protocol. RT is a promising intervention that can be employed by pediatric nurses to assist mothers in the home management of technology-dependent children. Copyright © 2014 Elsevier Inc. All rights reserved.

Reducing the Need for Personal Supports among Workers with Autism Using an iPod Touch as an Assistive Technology: Delayed Randomized Control Trial

Science.gov (United States)

Gentry, Tony; Kriner, Richard; Sima, Adam; McDonough, Jennifer; Wehman, Paul

2015-01-01

Personal digital assistants (PDAs) are versatile task organizers that hold promise as assistive technologies for people with cognitive-behavioral challenges. This delayed randomized controlled trial compared two groups of adult workers with autism spectrum disorder (ASD) to determine whether the use of an Apple iPod Touch PDA as a vocational…

Electric Holding Company Areas

Data.gov (United States)

Department of Homeland Security — Holding companies are electric power utilities that have a holding company structure. This vector polygon layer represents the area served by electric power holding...

Commercialization of IGCC technology looks promising

International Nuclear Information System (INIS)

Smith, D.J.

1992-01-01

This paper reports that a major focus of the latest round of the U.S. Department of Energy's Clean Coal Technology Program was three large-scale, high-efficiency electricity generating projects which will rely on coal gasification rather than burning the coal directly. The three projects are: Toms Creek integrated gasification combined-cycle (IGCC) demonstration project. The aim of the project is to demonstrate improved coal-to-power efficiencies in an integrated gasification combined-cycle process. According to the DOE, the Toms Creek project will show that significant reductions in SO 2 and NO x emissions can be accomplished through the use of IGCC technology. On completion of the project, 107 MW of electric capacity will be added to the grid. Pinon Pine IGCC power project. The project's aim is to demonstrate that IGCC plants can be constructed at significantly lower capital costs, and with higher thermal efficiencies, than conventional power generation technologies. It will also demonstrate the effectiveness of hot gas cleanup for low-sulfur western coals. Wasbash River coal gasification repowering project

Fulfilling a Promise: Standards for Technological Literacy.

Science.gov (United States)

Bybee, Rodger W.

2003-01-01

Discusses the place of standards in U.S. education, the development of the Standards for Technological Literacy, and the recent publication of "Advancing Excellence in Technological Literacy: Student Assessment, Professional Development, and Program Standards." (Contains 21 references.) (SK)

Influence of IR sensor technology on the military and civil defense

Science.gov (United States)

Becker, Latika

2006-02-01

Advances in basic infrared science and developments in pertinent technology applications have led to mature designs being incorporated in civil as well as military area defense systems. Military systems include both tactical and strategic, and civil area defense includes homeland security. Technical challenges arise in applying infrared sensor technology to detect and track targets for space and missile defense. Infrared sensors are valuable due to their passive capability, lower mass and power consumption, and their usefulness in all phases of missile defense engagements. Nanotechnology holds significant promise in the near future by offering unique material and physical properties to infrared components. This technology is rapidly developing. This presentation will review the current IR sensor technology, its applications, and future developments that will have an influence in military and civil defense applications.

Controllable deterioration rate for time-dependent demand and time-varying holding cost

Directory of Open Access Journals (Sweden)

Mishra Vinod Kumar

2014-01-01

Full Text Available In this paper, we develop an inventory model for non-instantaneous deteriorating items under the consideration of the facts: deterioration rate can be controlled by using the preservation technology (PT during deteriorating period, and holding cost and demand rate both are linear function of time, which was treated as constant in most of the deteriorating inventory models. So in this paper, we developed a deterministic inventory model for non-instantaneous deteriorating items in which both demand rate and holding cost are a linear function of time, deterioration rate is constant, backlogging rate is variable and depend on the length of the next replenishment, shortages are allowed and partially backlogged. The model is solved analytically by minimizing the total cost of the inventory system. The model can be applied to optimizing the total inventory cost of non-instantaneous deteriorating items inventory for the business enterprises, where the preservation technology is used to control the deterioration rate, and demand & holding cost both are a linear function of time.

31 CFR 800.217 - Hold.

Science.gov (United States)

2010-07-01

... and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF INVESTMENT... FOREIGN PERSONS Definitions § 800.217 Hold. The terms hold(s) and holding mean legal or beneficial ownership, whether direct or indirect, whether through fiduciaries, agents, or other means. ...

Holding the Edge: Maintaining the Defense Technology Base

Science.gov (United States)

1989-04-01

psychological , with the shedding of isolationist technology that is close or equal to that of the United attitudes and inhibitions. Reaction by European States...are directed toward aleveling could work against what should be a good common set of enabling technologies, with applica- leeida carld work aanst

Effects of Calcination Holding Time on Properties of Wide Band Gap Willemite Semiconductor Nanoparticles by the Polymer Thermal Treatment Method

Directory of Open Access Journals (Sweden)

Ibrahim Mustapha Alibe

2018-04-01

Full Text Available Willemite is a wide band gap semiconductor used in modern day technology for optoelectronics application. In this study, a new simple technique with less energy consumption is proposed. Willemite nanoparticles (NPs were produced via a water–based solution consisting of a metallic precursor, polyvinylpyrrolidone (PVP, and underwent a calcination process at 900 °C for several holding times between 1–4 h. The FT–IR and Raman spectra indicated the presence of metal oxide bands as well as the effective removal of PVP. The degree of the crystallization and formation of the NPs were determined by XRD. The mean crystallite size of the NPs was between 18.23–27.40 nm. The morphology, particle shape and size distribution were viewed with HR-TEM and FESEM analysis. The willemite NPs aggregate from the smaller to larger particles with an increase in calcination holding time from 1–4 h with the sizes ranging between 19.74–29.71 nm. The energy values obtained from the experimental band gap decreased with increasing the holding time over the range of 5.39 eV at 1 h to at 5.27 at 4 h. These values match well with band gap obtained from the Mott and Davis model for direct transition. The findings in this study are very promising and can justify the use of these novel materials as a potential candidate for green luminescent optoelectronic applications.

Usability of Particle Film Technology and Water Holding Materials to Improve Drought Tolerance in Gossypium hirsutum L. Plants

Science.gov (United States)

Roy, K.; Zwieniecki, M.

2017-12-01

Cotton (Gossypium hirsutum L.) is relatively drought resistant and thus is planted widely in many semi-arid and arid parts of the world, many of which are usually deprived of modern water management technologies. Since the productivity of cotton plants depends on water availability, we carried out the present research aiming at testing two different low cost and arid-environment friendly water efficient techniques: application of particle film technology on leaves to reduce the transpiration rate (kaolin dust), and use of organic material to improve the soil water holding capacity (cotton wool). In details, kaolin (3% and 5%; weight:volume) mixed in water was sprayed on the upper surface of the leaves of young plants, and small amounts of cotton wool (0.1%, 0.3% and 0.5%; weight:weight) were mixed into the soils. The study showed that kaolin spray was useful as a transpiration reducing agent only if plants have adequate water in the soil (well irrigated) but not under water stress conditions. In addition, mixing a small amount of cotton wool into the soil can significantly increase the amount of water available to the plants, and extend the benefit of kaolin application on plants.

Three-dimensional imaging technology offers promise in medicine.

Science.gov (United States)

Karako, Kenji; Wu, Qiong; Gao, Jianjun

2014-04-01

Medical imaging plays an increasingly important role in the diagnosis and treatment of disease. Currently, medical equipment mainly has two-dimensional (2D) imaging systems. Although this conventional imaging largely satisfies clinical requirements, it cannot depict pathologic changes in 3 dimensions. The development of three-dimensional (3D) imaging technology has encouraged advances in medical imaging. Three-dimensional imaging technology offers doctors much more information on a pathology than 2D imaging, thus significantly improving diagnostic capability and the quality of treatment. Moreover, the combination of 3D imaging with augmented reality significantly improves surgical navigation process. The advantages of 3D imaging technology have made it an important component of technological progress in the field of medical imaging.

Survey of Promising Technologies for 5G Networks

OpenAIRE

Le, Nam Tuan; Hossain, Mohammad Arif; Islam, Amirul; Kim, Do-yun; Choi, Young-June; Jang, Yeong Min

2016-01-01

As an enhancement of cellular networks, the future-generation 5G network can be considered an ultra-high-speed technology. The proposed 5G network might include all types of advanced dominant technologies to provide remarkable services. Consequently, new architectures and service management schemes for different applications of the emerging technologies need to be recommended to solve issues related to data traffic capacity, high data rate, and reliability for ensuring QoS. Cloud computing, I...

Biomolecular simulations on petascale: promises and challenges

International Nuclear Information System (INIS)

Agarwal, Pratul K; Alam, Sadaf R

2006-01-01

Proteins work as highly efficient machines at the molecular level and are responsible for a variety of processes in all living cells. There is wide interest in understanding these machines for implications in biochemical/biotechnology industries as well as in health related fields. Over the last century, investigations of proteins based on a variety of experimental techniques have provided a wealth of information. More recently, theoretical and computational modeling using large scale simulations is providing novel insights into the functioning of these machines. The next generation supercomputers with petascale computing power, hold great promises as well as challenges for the biomolecular simulation scientists. We briefly discuss the progress being made in this area

[Absorbable coronary stents. New promising technology].

Science.gov (United States)

Erbel, Raimund; Böse, Dirk; Haude, Michael; Kordish, Igor; Churzidze, Sofia; Malyar, Nasser; Konorza, Thomas; Sack, Stefan

2007-06-01

Coronary stent implantation started in Germany 20 years ago. In the beginning, the progress was very slow and accelerated 10 years later. Meanwhile, coronary stent implantation is a standard procedure in interventional cardiology. From the beginning of permanent stent implantation, research started to provide temporary stenting of coronary arteries, first with catheter-based systems, later with stent-alone technology. Stents were produced from polymers or metal. The first polymer stent implantation failed except the Igaki-Tamai stent in Japan. Newly developed absorbable polymer stents seem to be very promising, as intravascular ultrasound (IVUS) and optical coherence tomography have demonstrated. Temporary metal stents were developed based on iron and magnesium. Currently, the iron stent is tested in peripheral arteries. The absorbable magnesium stent (Biotronik, Berlin, Germany) was tested in peripheral arteries below the knee and meanwhile in the multicenter international PROGRESS-AMS (Clinical Performance and Angiographic Results of Coronary Stenting with Absorbable Metal Stents) study. The first magnesium stent implantation was performed on July 30, 2004 after extended experimental testing in Essen. The magnesium stent behaved like a bare-metal stent with low recoil of 5-7%. The stent struts were absorbed when tested with IVUS. Stent struts were not visible by fluoroscopy or computed tomography (CT) as well as magnetic resonance imaging (MRI). That means, that the magnesium stent is invisible and therefore CT and MRI can be used for imaging of interventions. Only using micro-CT the stent struts were visible. The absorption process could be demonstrated in a patient 18 days after implantation due to suspected acute coronary syndrome, which was excluded. IVUS showed a nice open lumen. Stent struts were no longer visible, but replaced by tissue indicating the previous stent location. Coronary angiography after 4 months showed an ischemia-driven target lesion

78 FR 23162 - Supervision and Regulation Assessments for Bank Holding Companies and Savings and Loan Holding...

Science.gov (United States)

2013-04-18

... bank holding company's Consolidated Financial Statements for Bank Holding Companies (FR Y-9C) forms; \\3... Balance Sheet of the BHC's Consolidated Financial Statements for Bank Holding Companies (FR Y-9C) (OMB No... holding companies with $50 billion or more in total consolidated assets, and nonbank financial companies...

Stem Cell Technology in Cardiac Regeneration: A Pluripotent Stem Cell Promise.

Science.gov (United States)

Duelen, Robin; Sampaolesi, Maurilio

2017-02-01

Despite advances in cardiovascular biology and medical therapy, heart disorders are the leading cause of death worldwide. Cell-based regenerative therapies become a promising treatment for patients affected by heart failure, but also underline the need for reproducible results in preclinical and clinical studies for safety and efficacy. Enthusiasm has been tempered by poor engraftment, survival and differentiation of the injected adult stem cells. The crucial challenge is identification and selection of the most suitable stem cell type for cardiac regenerative medicine. Human pluripotent stem cells (PSCs) have emerged as attractive cell source to obtain cardiomyocytes (CMs), with potential applications, including drug discovery and toxicity screening, disease modelling and innovative cell therapies. Lessons from embryology offered important insights into the development of stem cell-derived CMs. However, the generation of a CM population, uniform in cardiac subtype, adult maturation and functional properties, is highly recommended. Moreover, hurdles regarding tumorigenesis, graft cell death, immune rejection and arrhythmogenesis need to be overcome in clinical practice. Here we highlight the recent progression in PSC technologies for the regeneration of injured heart. We review novel strategies that might overcome current obstacles in heart regenerative medicine, aiming at improving cell survival and functional integration after cell transplantation. Copyright © 2017. Published by Elsevier B.V.

Stem Cell Technology in Cardiac Regeneration: A Pluripotent Stem Cell Promise

Directory of Open Access Journals (Sweden)

Robin Duelen

2017-02-01

Full Text Available Despite advances in cardiovascular biology and medical therapy, heart disorders are the leading cause of death worldwide. Cell-based regenerative therapies become a promising treatment for patients affected by heart failure, but also underline the need for reproducible results in preclinical and clinical studies for safety and efficacy. Enthusiasm has been tempered by poor engraftment, survival and differentiation of the injected adult stem cells. The crucial challenge is identification and selection of the most suitable stem cell type for cardiac regenerative medicine. Human pluripotent stem cells (PSCs have emerged as attractive cell source to obtain cardiomyocytes (CMs, with potential applications, including drug discovery and toxicity screening, disease modelling and innovative cell therapies. Lessons from embryology offered important insights into the development of stem cell-derived CMs. However, the generation of a CM population, uniform in cardiac subtype, adult maturation and functional properties, is highly recommended. Moreover, hurdles regarding tumorigenesis, graft cell death, immune rejection and arrhythmogenesis need to be overcome in clinical practice. Here we highlight the recent progression in PSC technologies for the regeneration of injured heart. We review novel strategies that might overcome current obstacles in heart regenerative medicine, aiming at improving cell survival and functional integration after cell transplantation.

Technology diffusion, product differentiation and environmental subsidies

Energy Technology Data Exchange (ETDEWEB)

McGinty, M. [Univ. of Wisconsin, Milwaukee, WI (United States). Dept. of Economics; Vries, F.P. de [Univ. of Groningen (Netherlands). Dept. of Law and Economics

2007-07-01

Technological change is often seen as the promising device that will mitigate or solve environmental problems. Policy intervention that spurs the development, adoption and diffusion of new, environmentally benign technologies therefore holds great appear for environmental authorities. Policymakers have various instruments at their disposal to affect technological diffusion, ranging from direct regulation (command-and-control strategies) to market-based instruments, such as taxes, subsidies and tradable pollution permits. This paper examines environmental subsidies as a technology diffusion policy. The authors apply evolutionary game theory to explore the relationship between subsidies for clean technology, the diffusion of that technology and the degree of product differentiation in an imperfectly competitive market. They show that the subsidy succeeds in reducing environmental damage only when the substitution effect (the reduction in pollution associated with the clean technology) exceeds the output effect (the extent that the subsidy increases output). When the substitution effect does dominate, environmental damage decreases monotonically during the diffusion process. The extent of diffusion (the degree to which clean technolgy replaces dirty) and the likelihood that the substitution effect will dominate both decrease with the extent of product differentiation. Finally, the subsidy for clean technology will spill over to the remaining dirty producers increasing their profit as well.

12 CFR 584.2-2 - Permissible bank holding company activities of savings and loan holding companies.

Science.gov (United States)

2010-01-01

... savings and loan holding companies. 584.2-2 Section 584.2-2 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SAVINGS AND LOAN HOLDING COMPANIES § 584.2-2 Permissible bank holding company activities of savings and loan holding companies. (a) General. For purposes of § 584.2(b)(6)(i) of this part...

The Promise of Technology. Proceedings of the Annual Conference on Rehabilitation Engineering (6th, San Diego, California, June 12-16, 1983). Volume 3.

Science.gov (United States)

Bowman, Bruce R., Ed.

These proceedings contain abstracts of 164 papers in the area of interdisciplinary rehabilitation research, focusing on the theme of "The Promise of Technology." The abstracts are organized into the following sections: "Home and Worksite Modification,""Computers and Microprocessor Systems,""Neuromuscular…

Communication technologies to improve HPV vaccination initiation and completion: A systematic review.

Science.gov (United States)

Francis, Diane B; Cates, Joan R; Wagner, Kyla P Garrett; Zola, Tracey; Fitter, Jenny E; Coyne-Beasley, Tamera

2017-07-01

This systematic review examines the effectiveness of communication technology interventions on HPV vaccination initiation and completion. A comprehensive search strategy was used to identify existing randomized controlled trials testing the impact of computer-, mobile- or internet-based interventions on receipt of any dose of the HPV vaccine. Twelve relevant studies were identified with a total of 38,945 participants. The interventions were delivered using several different methods, including electronic health record (i.e. recall/reminder) prompts, text messaging, automated phone calls, interactive computer videos, and email. Vaccine initiation and completion was greater for technology-based studies relative to their control conditions. There is evidence that interventions utilizing communication technologies as their sole or primary mode for HPV vaccination intervention delivery may increase vaccination coverage. Communication technologies hold much promise for the future of HPV vaccination efforts, especially initiatives in practice-based settings. Copyright © 2017 Elsevier B.V. All rights reserved.

Do biological-based strategies hold promise to biofouling control in MBRs?

KAUST Repository

Malaeb, Lilian

2013-10-01

Biofouling in membrane bioreactors (MBRs) remains a primary challenge for their wider application, despite the growing acceptance of MBRs worldwide. Research studies on membrane fouling are extensive in the literature, with more than 200 publications on MBR fouling in the last 3 years; yet, improvements in practice on biofouling control and management have been remarkably slow. Commonly applied cleaning methods are only partially effective and membrane replacement often becomes frequent. The reason for the slow advancement in successful control of biofouling is largely attributed to the complex interactions of involved biological compounds and the lack of representative-for-practice experimental approaches to evaluate potential effective control strategies. Biofouling is driven by microorganisms and their associated extra-cellular polymeric substances (EPS) and microbial products. Microorganisms and their products convene together to form matrices that are commonly treated as a black box in conventional control approaches. Biological-based antifouling strategies seem to be a promising constituent of an effective integrated control approach since they target the essence of biofouling problems. However, biological-based strategies are in their developmental phase and several questions should be addressed to set a roadmap for translating existing and new information into sustainable and effective control techniques. This paper investigates membrane biofouling in MBRs from the microbiological perspective to evaluate the potential of biological-based strategies in offering viable control alternatives. Limitations of available control methods highlight the importance of an integrated anti-fouling approach including biological strategies. Successful development of these strategies requires detailed characterization of microorganisms and EPS through the proper selection of analytical tools and assembly of results. Existing microbiological/EPS studies reveal a number of

Realising the technological promise of smartphones in addiction research and treatment: An ethical review.

Science.gov (United States)

Capon, Hannah; Hall, Wayne; Fry, Craig; Carter, Adrian

2016-10-01

Smartphone technologies and mHealth applications (or apps) promise unprecedented scope for data collection, treatment intervention, and relapse prevention when used in the field of substance abuse and addiction. This potential also raises new ethical challenges that researchers, clinicians, and software developers must address. This paper aims to identify ethical issues in the current uses of smartphones in addiction research and treatment. A search of three databases (PubMed, Web of Science and PsycInfo) identified 33 studies involving smartphones or mHealth applications for use in the research and treatment of substance abuse and addiction. A content analysis was conducted to identify how smartphones are being used in these fields and to highlight the ethical issues raised by these studies. Smartphones are being used to collect large amounts of sensitive information, including personal information, geo-location, physiological activity, self-reports of mood and cravings, and the consumption of illicit drugs, alcohol and nicotine. Given that detailed information is being collected about potentially illegal behaviour, we identified the following ethical considerations: protecting user privacy, maximising equity in access, ensuring informed consent, providing participants with adequate clinical resources, communicating clinically relevant results to individuals, and the urgent need to demonstrate evidence of safety and efficacy of the technologies. mHealth technology offers the possibility to collect large amounts of valuable personal information that may enhance research and treatment of substance abuse and addiction. To realise this potential researchers, clinicians and app-developers must address these ethical concerns to maximise the benefits and minimise risks of harm to users. Copyright © 2016 Elsevier B.V. All rights reserved.

12 CFR 225.82 - How does a bank holding company elect to become a financial holding company?

Science.gov (United States)

2010-01-01

... holding company to become a financial holding company shall not be effective if, during the period...) Effective date of election—(1) In general. An election filed by a bank holding company under paragraph (a... financial holding company is effective prior to the 31st day after the date that a complete declaration was...

Fuelling expectations: A policy-promise lock-in of UK biofuel policy

International Nuclear Information System (INIS)

Berti, Pietro; Levidow, Les

2014-01-01

Controversy over EU-wide biofuel policy resonated within the UK, fuelling policy disagreements among UK public authorities. They disagreed over how to protect a space for future second-generation biofuels, which were expected to overcome harm from first-generation biofuels. The UK government defended rising targets for available biofuels as a necessary stimulus for industry to help fulfil the UK's EU obligations and eventually develop second-generation biofuels. By contrast, Parliamentary Select Committees opposed biofuel targets on grounds that these would instead lock-in first-generation biofuels, thus delaying or pre-empting second-generation biofuels. Those disagreements can be explained by different institutional responsibilities and reputational stakes towards ‘promise-requirement cycles’, whereby techno-optimistic promises generate future requirements for the actors involved. The UK government's stance illustrates a ‘policy-promise lock-in’, a dilemma whereby promised support is a requirement for credibility towards technology innovators and thus technoscientific development – but may delay the redirection of support from incumbent to preferable emerging technologies. Thus the sociology of expectations – previously applied to technological expectations from technology innovators – can be extended to analyse public authorities. - Highlights: • Controversy over EU-wide biofuel policy resonated within the UK. • At issue was how to stimulate future 2nd-generation biofuels. • The government defended targets for 1st-generation as necessary to stimulate industry. • Parliamentary Committees opposed biofuel targets as locking in 1st-generation. • The UK government′s stance illustrates a ‘policy-promise lock-in’

SPECIALIZATION AND SUSTAINABLE DEVELOPMENT OF AGRICULTURAL HOLDINGS

Directory of Open Access Journals (Sweden)

Zofia Kołoszko-Chomentowska

2016-03-01

Full Text Available In the present article, an attempt was made to assess the sustainability of agricultural holdings with diff erent directions of production. Agricultural holdings in the Podlaskie voivodeship registered in the FADN system in 2011–2012 were investigated. Assessment accounted for agroecological indicators (share of permanent grasslands, share of cereals in crops, soil coverage with vegetation, stock density and economic indicators (profi tableness of land and labor. Analysis was conducted according to a classifi cation into agricultural holding types: fi eldcrops, dairy cattle, and granivores. Fieldcrop and granivore holdings achieved more favourable environmental sustainability indicators. Holdings specializing in dairy cattle breeding posed a threat to the natural environment, mainly due to their excessive stock density. Economic sustainability assessment showed that granivore holdings were assessed most favorably. In these holdings, holding income per full-time worker was 37% greater than in fi eldcrop holdings and 57% greater than in dairy cattle holdings.

Emerging technologies in arthroplasty: additive manufacturing.

Science.gov (United States)

Banerjee, Samik; Kulesha, Gene; Kester, Mark; Mont, Michael A

2014-06-01

Additive manufacturing is an industrial technology whereby three-dimensional visual computer models are fabricated into physical components by selectively curing, depositing, or consolidating various materials in consecutive layers. Although initially developed for production of simulated models, the technology has undergone vast improvements and is currently increasingly being used for the production of end-use components in various aerospace, automotive, and biomedical specialties. The ability of this technology to be used for the manufacture of solid-mesh-foam monolithic and coated components of complex geometries previously considered unmanufacturable has attracted the attention of implant manufacturers, bioengineers, and orthopedic surgeons. Currently, there is a paucity of reports describing this fabrication method in the orthopedic literature. Therefore, we aimed to briefly describe this technology, some of the applications in other orthopedic subspecialties, its present use in hip and knee arthroplasty, and concerns with the present form of the technology. As there are few reports of clinical trials presently available, the true benefits of this technology can only be realized when studies evaluating the clinical and radiographic outcomes of cementless implants manufactured with additive manufacturing report durable fixation, less stress shielding, and better implant survivorship. Nevertheless, the authors believe that this technology holds great promise and may potentially change the conventional methods of casting, machining, and tooling for implant manufacturing in the future. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Inflation, operating cycle, and cash holdings

Directory of Open Access Journals (Sweden)

Yanchao Wang

2014-12-01

Full Text Available A corporate cash-holding strategy is a trade-off between the costs and benefits of holding cash. At the macrolevel, firms are inclined to adjust and optimize their cash-holding strategies in response to changes in purchasing power due to inflation. At the microlevel, the operating cycle, which indicates the speed and turnover of corporate cash flow, also influences the corporate cash-holding strategy. Firms flexibly adjust their cash-holding strategies in response to changes in the internal and external environment, which is referred to as the cash adjustment strategy. We examine these predicted relationships using a sample of listed firms in China’s stock market over the 1998–2009 period. Consistent with our predictions, the empirical results indicate a significant negative association between cash holdings and the CPI, but the relationship is reversed when the CPI reaches a certain level. There is also a U-shaped relationship between operating cycle and cash holdings, and this relationship is similarly influenced by changes in the inflation level. In examining the macroeconomic environment and microlevel firm-specific characteristics simultaneously, our findings supplement the literature on firms’ cash-holding strategies and provide theoretical and practical implications.

The promises of stem cells: stem cell therapy for movement disorders.

Science.gov (United States)

Mochizuki, Hideki; Choong, Chi-Jing; Yasuda, Toru

2014-01-01

Despite the multitude of intensive research, the exact pathophysiological mechanisms underlying movement disorders including Parkinson's disease, multiple system atrophy and Huntington's disease remain more or less elusive. Treatments to halt these disease progressions are currently unavailable. With the recent induced pluripotent stem cells breakthrough and accomplishment, stem cell research, as the vast majority of scientists agree, holds great promise for relieving and treating debilitating movement disorders. As stem cells are the precursors of all cells in the human body, an understanding of the molecular mechanisms that govern how they develop and work would provide us many fundamental insights into human biology of health and disease. Moreover, stem-cell-derived neurons may be a renewable source of replacement cells for damaged neurons in movement disorders. While stem cells show potential for regenerative medicine, their use as tools for research and drug testing is thought to have more immediate impact. The use of stem-cell-based drug screening technology could be a big boost in drug discovery for these movement disorders. Particular attention should also be given to the involvement of neural stem cells in adult neurogenesis so as to encourage its development as a therapeutic option. Copyright © 2013 Elsevier Ltd. All rights reserved.

Ultrasonic methods for locating hold-up

International Nuclear Information System (INIS)

Sinha, D.N.; Olinger, C.T.

1995-01-01

Hold-up remains one of the major contributing factors to unaccounted for materials and can be a costly problem in decontamination and decommissioning activities. Ultrasonic techniques are being developed to noninvasively monitor hold-up in process equipment where the inner surface of such equipment may be in contact with the hold-up material. These techniques may be useful in improving hold-up measurements as well as optimizing decontamination techniques

Search Technologies | NCI Technology Transfer Center | TTC

Science.gov (United States)

Our team of technology transfer specialists has specialized training in invention reporting, patenting, patent strategy, executing technology transfer agreements and marketing. TTC is comprised of professionals with diverse legal, scientific, and business/marketing expertise. Most of our staff hold doctorate-level technical and/or legal training.

Available Technologies | NCI Technology Transfer Center | TTC

Science.gov (United States)

Our team of technology transfer specialists has specialized training in invention reporting, patenting, patent strategy, executing technology transfer agreements and marketing. TTC is comprised of professionals with diverse legal, scientific, and business/marketing expertise. Most of our staff hold doctorate-level technical and/or legal training.

The Impact of “Omic” and Imaging Technologies on Assessing the Host Immune Response to Biodefence Agents

Directory of Open Access Journals (Sweden)

Julia A. Tree

2014-01-01

Full Text Available Understanding the interactions between host and pathogen is important for the development and assessment of medical countermeasures to infectious agents, including potential biodefence pathogens such as Bacillus anthracis, Ebola virus, and Francisella tularensis. This review focuses on technological advances which allow this interaction to be studied in much greater detail. Namely, the use of “omic” technologies (next generation sequencing, DNA, and protein microarrays for dissecting the underlying host response to infection at the molecular level; optical imaging techniques (flow cytometry and fluorescence microscopy for assessing cellular responses to infection; and biophotonic imaging for visualising the infectious disease process. All of these technologies hold great promise for important breakthroughs in the rational development of vaccines and therapeutics for biodefence agents.

Holding fast.

Science.gov (United States)

Gourville, John T

2005-06-01

CEO Peter Walsh faces a classic innovator's dilemma. His company, Crescordia, produces high-quality metal plates, pins, and screws that orthopedic surgeons use to repair broken bones. In fact, because the company has for decades refused to compromise on quality, there are orthopedic surgeons who use nothing but Crescordia hardware. And now these customers have begun to clamor for the next generation technology: resorbable hardware. Resorbables offer clear advantages over the traditional hardware. Like dissolving sutures, resorbable plates and screws are made of biodegradable polymers. They hold up long enough to support a healing bone, then gradually and harmlessly disintegrate in the patient's body. Surgeons are especially looking forward to using resorbables on children, so kids won't have to undergo a second operation to remove the old hardware after their bones heal, a common procedure in pediatrics. The new products, however, are not yet reliable; they fail about 8% of the time, sometimes disintegrating before the bone completely heals and sometimes not ever fully disintegrating. That's why Crescordia, mindful of its hard-earned reputation, has delayed launching a line using the new technology. But time is running out. A few competitors have begun to sell resorbables despite their imperfections, and these companies are picking up market share. Should Crescordia join the fray and risk tarnishing its brand? Or should the company sit tight until it can offer a perfect product? Commenting on this fictional case study are Robert A. Lutz, vice chairman of product development at General Motors; Clayton M. Christensen, the Robert and Jane Cizik Professor of Business Administration at Harvard Business School; Jason Wittes, a senior equity analyst covering medical supplies and devices at Leerink Swann; and Nick Galakatos, a general partner of MPM Capital.

Tube holding system

International Nuclear Information System (INIS)

Cunningham, R.C.

1978-01-01

A tube holding rig is described for the lateral support of tubes arranged in tight parcels in a heat exchanger. This tube holding rig includes not less than two tube supporting assemblies, with a space between them, located crosswise with respect to the tubes, each supporting assembly comprising a first set of parallel components in contact with the tubes, whilst a second set of components is also in contact with the tubes. These two sets of parts together define apertures through which the tubes pass [fr

eHealth Applications Promising Strategies for Behavior Change

CERN Document Server

Noar, Seth M

2012-01-01

eHealth Applications: Promising Strategies for Behavior Change provides an overview of technological applications in contemporary health communication research, exploring the history and current uses of eHealth applications in disease prevention and management. This volume focuses on the use of these technology-based interventions for public health promotion and explores the rapid growth of an innovative interdisciplinary field. The chapters in this work discuss key eHealth applications by presenting research examining a variety of technology-based applications. Authors Seth M. Noar and Nancy

UWB Technology and Applications on Space Exploration

Science.gov (United States)

Ngo, Phong; Phan, Chau; Gross, Julia; Dusl, John; Ni, Jianjun; Rafford, Melinda

2006-01-01

Ultra-wideband (UWB), also known as impulse or carrier-free radio technology, is one promising new technology. In February 2002, the Federal Communications Commission (FCC) approved the deployment of this technology. It is increasingly recognized that UWB technology holds great potential to provide significant benefits in many terrestrial and space applications such as precise positioning/tracking and high data rate mobile wireless communications. This talk presents an introduction to UWB technology and some applications on space exploration. UWB is characterized by several uniquely attractive features, such as low impact on other RF systems due to its extremely low power spectral densities, immunity to interference from narrow band RF systems due to its ultra-wide bandwidth, multipath immunity to fading due to ample multipath diversity, capable of precise positioning due to fine time resolution, capable of high data rate multi-channel performance. The related FCC regulations, IEEE standardization efforts and industry activities also will be addressed in this talk. For space applications, some projects currently under development at NASA Johnson Space Center will be introduced. These include the UWB integrated communication and tracking system for Lunar/Mars rover and astronauts, UWB-RFID ISS inventory tracking, and UWB-TDOA close-in high resolution tracking for potential applications on robonaut.

The E-Book: Technological Promise for Learning.

Science.gov (United States)

Galbreath, Jeremy

2001-01-01

Explores the concept of electronic books and how they fit in with educational technology. Topics include new portable devices that store multiple electronic books; multimedia capabilities; the ability to connect with other electronic devices, including computer networks; and future possibilities that may depend on the acceptance of change. (LRW)

Digital Actuator Technology

Energy Technology Data Exchange (ETDEWEB)

Ken Thomas; Ted Quinn; Jerry Mauck; Richard Bockhorst

2014-09-01

There are significant developments underway in new types of actuators for power plant active components. Many of these make use of digital technology to provide a wide array of benefits in performance of the actuators and in reduced burden to maintain them. These new product offerings have gained considerable acceptance in use in process plants. In addition, they have been used in conventional power generation very successfully. This technology has been proven to deliver the benefits promised and substantiate the claims of improved performance. The nuclear industry has been reluctant to incorporate digital actuator technology into nuclear plant designs due to concerns due to a number of concerns. These could be summarized as cost, regulatory uncertainty, and a certain comfort factor with legacy analog technology. The replacement opportunity for these types of components represents a decision point for whether to invest in more modern technology that would provide superior operational and maintenance benefits. Yet, the application of digital technology has been problematic for the nuclear industry, due to qualification and regulatory issues. With some notable exceptions, the result has been a continuing reluctance to undertake the risks and uncertainties of implementing digital actuator technology when replacement opportunities present themselves. Rather, utilities would typically prefer to accept the performance limitations of the legacy analog actuator technologies to avoid impacts to project costs and schedules. The purpose of this report is to demonstrate that the benefits of digital actuator technology can be significant in terms of plant performance and that it is worthwhile to address the barriers currently holding back the widespread development and use of this technology. It addresses two important objectives in pursuit of the beneficial use of digital actuator technology for nuclear power plants: 1. To demonstrate the benefits of digital actuator

Early prediction of water-holding capacity in meat by multivariate vibrational spectroscopy

DEFF Research Database (Denmark)

Pedersen, D.K.; Morel, S.; Engelsen, S.B.

2003-01-01

about the water-holding capacity (WHC) of the meat. Preliminary studies performed at a research slaughterhouse revealed a high correlation between WHC and both IR (r=0.89) and Raman spectra using Partial Least Squares Regressions (PLSR). The good results were confirmed under industrial conditions using...... FT-IR at-line spectroscopy. However, the latter experiment yielded a somewhat lower correlation (r=0.79). This result is, however, promising for the purpose of finding a method for classification of carcasses with regard to WHC at the slaughter line. The IR region 1800–900 cm−1 contains the best...

The Impact of Sustainable Development Technology on a Small Economy-The Case of Energy-Saving Technology.

Science.gov (United States)

Chen, Xiding; Huang, Qinghua; Huang, Weilun; Li, Xue

2018-02-08

We investigated the impact of a sustainable development technology on the macroeconomic variables in a small economy utilizing a case study with a stochastically improving energy saving technology and a stochastically increasing energy price. The results show the technological displacement effects of energy saving technology are stronger, but there are more ambiguous instantaneous returns to physical capital. However, the energy saving technology's displacement effects might not affect the conditions under which the Harberger-Laursen-Metzler (HLM) effect holds. The effects of rising energy prices on bonds are stronger, and there are more ambiguous instantaneous returns, but the conditions under which the HLM effect holds are different.

Regulation of Cross-holdings between European Companies

DEFF Research Database (Denmark)

Sørensen, Karsten Engsig

2003-01-01

Cross-holdings can be a barrier to takeovers, and they may have other disadvantages. This article analyses how cross-holdings may be regulated to avoid these negative effects.......Cross-holdings can be a barrier to takeovers, and they may have other disadvantages. This article analyses how cross-holdings may be regulated to avoid these negative effects....

Metal shell technology based upon hollow jet instability

International Nuclear Information System (INIS)

Kendall, J.M.; Lee, M.C.; Wang, T.G.

1982-01-01

Spherical shells of submillimeter size are sought as ICF targets. Such shells must be dimensionally precise, smooth, of high strength, and composed of a high atomic number material. We describe a technology for the production of shells based upon the hydrodynamic instability of an annular jet of molten metal. We have produced shells in the 0.7--2.0 mm size range using tin as a test material. Specimens exhibit good sphericity, fair concentricity, and excellent finish over most of the surface. Work involving a gold--lead--antimony alloy is in progress. Droplets of this are amorphous and possess superior surface finish. The flow of tin models that of the alloy well; experiments on both metals show that the technique holds considerable promise

Collective behaviors of book holding durations

Science.gov (United States)

Li, Ren-De; Guo, Qiang; Han, Jing-Ti; Liu, Jian-Guo

2016-10-01

Duration can directly reflect the collective reading behaviors of library user book holding. In this paper, by introducing the burstiness and memory coefficients, we empirically investigate the collective book holding behavior of three university libraries. The statistical results show that there are similar properties among the students with different backgrounds, presenting the burstiness = - 0.2 and memory = 0.5 for three datasets, which indicates that memory and random effects coexist in student book holding durations. In addition, we analyze the behavior patterns without duplicate durations by merging a series of books borrowed and returned at the same time. The results show the average burstiness B increases to -0.16 and memory M drops to 0.16 for three datasets, which indicates that both duplicate behavior and student's preference affect the memory effect. Furthermore, we present a model which assumes student's next book holding duration follows the previous one with probability p, and with probability 1 - p, the student would hold the book independently. The experimental results show that the presented model can reproduce the burstiness and memory effect of student book holding durations when p = 0.5 for empirical datasets and p = 0.2 for de-duplicate datasets, which indicate that the student's preferential holding behavior occurs with the probability p. This work helps in deeply understanding the regularity of duration-based human behaviors.

Translation regulation in plants: an interesting past, an exciting present and a promising future.

Science.gov (United States)

Merchante, Catharina; Stepanova, Anna N; Alonso, Jose M

2017-05-01

Changes in gene expression are at the core of most biological processes, from cell differentiation to organ development, including the adaptation of the whole organism to the ever-changing environment. Although the central role of transcriptional regulation is solidly established and the general mechanisms involved in this type of regulation are relatively well understood, it is clear that regulation at a translational level also plays an essential role in modulating gene expression. Despite the large number of examples illustrating the critical role played by translational regulation in determining the expression levels of a gene, our understanding of the molecular mechanisms behind such types of regulation has been slow to emerge. With the recent development of high-throughput approaches to map and quantify different critical parameters affecting translation, such as RNA structure, protein-RNA interactions and ribosome occupancy at the genome level, a renewed enthusiasm toward studying translation regulation is warranted. The use of these new powerful technologies in well-established and uncharacterized translation-dependent processes holds the promise to decipher the likely complex and diverse, but also fascinating, mechanisms behind the regulation of translation. © 2017 The Authors The Plant Journal © 2017 John Wiley & Sons Ltd.

Considerations for Realizing the Promise of Educational Gaming Technology

Science.gov (United States)

Nelson, Nancy J.; Fien, Hank; Doabler, Christian T.; Clarke, Ben

2016-01-01

Hope Elementary School recently purchased tablets for all of its students to facilitate the use of technology in the classroom. The principal at Hope Elementary understands that technology can be an efficient and effective way for teachers to access materials and differentiate instruction to support the achievement of all learners. However, some…

NOx emission control for gas turbines: A 1991 update on regulations and technology (Part II)

International Nuclear Information System (INIS)

Schorr, M.M.

1991-01-01

The technologies that are available for the control of NO x emissions from gas turbines utilize the factors that impact the formation of NO x described in the previous section and include (1) diluent injection (i.e., water or steam) into the combustion zone, which is a front-end control technology that lowers the combustor flame temperature, (2) selective catalytic reduction (SCR), which is a back-end exhaust gas cleanup system, (3) dry low NO x combustors (DLN), which use staged combustion and very lean fuel-air mixtures (they are currently being introduced), and (4) catalytic combustion systems that hold the promise of achieving extremely low emission levels without resorting to exhaust gas cleanup. This last option is being developed to burn very lean fuel-air mixtures, but will require significant technological breakthroughs; it is still several years away from becoming commercially available

Using mobile phone technology to provide recovery support for women offenders.

Science.gov (United States)

Scott, Christy K; Johnson, Kimberly; Dennis, Michael L

2013-10-01

Mobile technology holds promise as a recovery tool for people with substance use disorders. However, some populations who may benefit the most may not have access to or experience with mobile phones. Incarcerated women represent a group at high risk for recidivism and relapse to substance abuse. Cost-effective mechanisms must be in place to support their recovery upon release. This study explores using mobile technology as a recovery management tool for women offenders residing in the community following release from jail. This study surveyed 325 minority women offenders with substance use disorders to determine whether or not they use cell phones, their comfort with texting and search features, and the social networks that they access from mobile phones. We found that 83% of survey subjects had cell phones; 30% of those were smartphones. Seventy-seven percent of the women reported access to supportive friends, and 88% had close family members they contacted regularly using mobile technology. Results indicated that most of the women were comfortable using a mobile phone, although the majority of them had prepaid minutes rather than plans, and most did currently use smartphones or have the capability to download applications or access social networks via their phones. Most women reported that they would be comfortable using a mobile phone to text, e-mail, and answer surveys. The high rate of adoption of mobile technology by women offenders makes them a promising target for recovery support delivered via mobile phone.

The promise of new ideas and new technology for improving teaching and learning.

Science.gov (United States)

Novak, Joseph D

2003-01-01

There have been enormous advances in our understanding of human learning in the past three decades. There have also been important advances in our understanding of the nature of knowledge and new knowledge creation. These advances, when combined with the explosive development of the Internet and other technologies, permit advances in educational practices at least as important as the invention of the printing press in 1460. We have built on the cognitive learning theory of David Ausubel and various sources of new ideas on epistemology. Our research program has focused on understanding meaningful learning and on developing better methods to achieve such learning and to assess progress in meaningful learning. The concept map tool developed in our program has proved to be highly effective both in promoting meaningful learning and in assessing learning outcomes. Concept mapping strategies are also proving powerful for eliciting, capturing, and archiving knowledge of experts and organizations. New technology for creating concept maps developed at the University of West Florida permits easier and better concept map construction, thus facilitating learning, knowledge capture, and local or distance creation and sharing of structured knowledge, especially when utilized with the Internet. A huge gap exists between what we now know to improve learning and use of knowledge and the practices currently in place in most schools and corporations. There are promising projects in progress that may help to achieve accelerated advances. These include projects in schools at all educational levels, including projects in Colombia, Costa Rica, Italy, Spain, and the United States, and collaborative projects with corporate organizations and distance learning projects. Results to date have been encouraging and suggest that we may be moving from the lag phase of educational innovation to a phase of exponential growth.

Artificial Intelligence and the Future of Education: Big Promises-Bigger Challenges%Artificial Intelligence and the Future of Education:Big Promises-Bigger Challenges

Institute of Scientific and Technical Information of China (English)

Jonathan Michael Spector; Du Jing

2017-01-01

The history of educational technology in the last 50 years contains few instances of dramatic improvements in learning based on the adoption of a particular technology.An example involving artificial intelligence occurred in the 1990s with the development of intelligent tutoring systems (ITSs).What happened with ITSs was that their success was limited to well-defined and relatively simple declarative and procedural leaming tasks (e.g.,learning how to write a recursive function in LISP;doing multi-column addition),and improvements that were observed tended to be more limited than promised (e.g.,one standard deviation improvement at best rather than the promised standard deviation improvement).Still,there was some progress in terms of how to conceptualize learning.A seldom documented limitation was the notion of only viewing learning from only content and cognitive perspectives (i.e.,in terms of memory limitations,prior knowledge,bug libraries,learning hierarchies and sequences etc.).Little attention was paid to education conceived more broadly than developing specific cognitive skills with highly constrained problems.New technologies offer the potential to create dynamic and multi-dimensional models of a particular leamer,and to track large data sets of learning activities,resources,interventions,and outcomes over a great many leamers.Using those data to personalize learning for a particular leamer developing knowledge,competence and understanding in a specific domain of inquiry is finally a real possibility.While the potential to make significant progress is clearly possible,the reality is less not so promising.There are many as yet unmet challenging some of which will be mentioned in this paper.A persistent worry is that educational technologists and computer scientists will again promise too much,too soon at too little cost and with too little effort and attention to the realities in schools and universities.

Breath-Hold Diving.

Science.gov (United States)

Fitz-Clarke, John R

2018-03-25

Breath-hold diving is practiced by recreational divers, seafood divers, military divers, and competitive athletes. It involves highly integrated physiology and extreme responses. This article reviews human breath-hold diving physiology beginning with an historical overview followed by a summary of foundational research and a survey of some contemporary issues. Immersion and cardiovascular adjustments promote a blood shift into the heart and chest vasculature. Autonomic responses include diving bradycardia, peripheral vasoconstriction, and splenic contraction, which help conserve oxygen. Competitive divers use a technique of lung hyperinflation that raises initial volume and airway pressure to facilitate longer apnea times and greater depths. Gas compression at depth leads to sequential alveolar collapse. Airway pressure decreases with depth and becomes negative relative to ambient due to limited chest compliance at low lung volumes, raising the risk of pulmonary injury called "squeeze," characterized by postdive coughing, wheezing, and hemoptysis. Hypoxia and hypercapnia influence the terminal breakpoint beyond which voluntary apnea cannot be sustained. Ascent blackout due to hypoxia is a danger during long breath-holds, and has become common amongst high-level competitors who can suppress their urge to breathe. Decompression sickness due to nitrogen accumulation causing bubble formation can occur after multiple repetitive dives, or after single deep dives during depth record attempts. Humans experience responses similar to those seen in diving mammals, but to a lesser degree. The deepest sled-assisted breath-hold dive was to 214 m. Factors that might determine ultimate human depth capabilities are discussed. © 2018 American Physiological Society. Compr Physiol 8:585-630, 2018. Copyright © 2018 American Physiological Society. All rights reserved.

EVALUATION OF THE IMPACT OF INNOVATIVE PROJECTS ON THE COMPETITIVENESS OF AGRICULTURAL HOLDINGS IN SLOVAK REPUBLIC

Directory of Open Access Journals (Sweden)

Ľubica RUMANOVSKÁ

2013-01-01

Full Text Available The scientific paper evaluates the impact of innovative projects on the competitiveness of agricultural holdings in SR. Evaluation of the impact of innovative projects on competitiveness of agricultural holdings was realized on the selected holdings in Nitra and Trnava region. For the evaluation was used RCR coefficient. With the use of RCR coefficient could be confirmed the scientific hypothesis - The innovative projects realized through Program for rural development SR 2007-2013 have positive impact on competitiveness of agricultural holdings. The possibilities for EU financial support for innovative projects in SR represent important source for introduction of new innovative technologies into production process and in future they can significantly contribute to the growth of competitiveness of agricultural subjects. Therefore, to increase competitiveness of agricultural holdings it is important to focus on modernization of machinery and buildings, use of natural sources for energy production, but also to increase the education and the flow of information between rural inhabitants, mainly farmers. In competitive area of EU agricultural sector it is necessary that agricultural holdings will innovate, not only to create independent flow of innovative products and knowledge, but also to increase its value on internal market. Agricultural holdings –receivers of financial support – have expressed the opinion that financial support realized through PRD SR 2007-2013 had definitely allowed them to implement new processes and products.

Mure skal holde zombierne ude

DEFF Research Database (Denmark)

Stockmarr, Leila

2013-01-01

Vi bygger som besatte mure og barrierer for at holde flygtninge ude og tæmme de negative konsekvenser af den neoliberale globalisering.......Vi bygger som besatte mure og barrierer for at holde flygtninge ude og tæmme de negative konsekvenser af den neoliberale globalisering....

The promise of two-person neuroscience for developmental psychiatry: Using interaction-based sociometrics to identify disorders of social interaction

OpenAIRE

Leong, Victoria; Schilbach, Leonhard

2018-01-01

Social interactions are fundamental for human development, and disordered social interactions are pervasive in many psychiatric disorders. Recent advances in “two-person neuroscience” have provided new tools for characterising social interactions. Accordingly, interaction-based ‘sociometrics’ hold great promise for developmental psychology and psychiatry, particularly in the early identification of social disorders.

The Scary Promise of Technology : Developing New Forms of Audience Research

NARCIS (Netherlands)

Dr. Joke Hermes

2012-01-01

Hoofdstuk 12 uit deel III: Uses of cultural technologies. The essays in this volume discuss both the culture of technology that we live in today, and culture as technology. Within the chapters of the book cultures of technology and cultural technologies are discussed, focussing on a variety of

The Impact of Sustainable Development Technology on a Small Economy—The Case of Energy-Saving Technology

Directory of Open Access Journals (Sweden)

Xiding Chen

2018-02-01

Full Text Available We investigated the impact of a sustainable development technology on the macroeconomic variables in a small economy utilizing a case study with a stochastically improving energy saving technology and a stochastically increasing energy price. The results show the technological displacement effects of energy saving technology are stronger, but there are more ambiguous instantaneous returns to physical capital. However, the energy saving technology’s displacement effects might not affect the conditions under which the Harberger-Laursen-Metzler (HLM effect holds. The effects of rising energy prices on bonds are stronger, and there are more ambiguous instantaneous returns, but the conditions under which the HLM effect holds are different.

The Impact of Sustainable Development Technology on a Small Economy—The Case of Energy-Saving Technology

Science.gov (United States)

Huang, Qinghua; Huang, Weilun; Li, Xue

2018-01-01

We investigated the impact of a sustainable development technology on the macroeconomic variables in a small economy utilizing a case study with a stochastically improving energy saving technology and a stochastically increasing energy price. The results show the technological displacement effects of energy saving technology are stronger, but there are more ambiguous instantaneous returns to physical capital. However, the energy saving technology’s displacement effects might not affect the conditions under which the Harberger-Laursen-Metzler (HLM) effect holds. The effects of rising energy prices on bonds are stronger, and there are more ambiguous instantaneous returns, but the conditions under which the HLM effect holds are different. PMID:29419788

Life cycle evaluation of emerging lignocellulosic ethanol conversion technologies.

Science.gov (United States)

Spatari, Sabrina; Bagley, David M; MacLean, Heather L

2010-01-01

Lignocellulosic ethanol holds promise for addressing climate change and energy security issues associated with personal transportation through lowering the fuel mixes' carbon intensity and petroleum demand. We compare the technological features and life cycle environmental impacts of near- and mid-term ethanol bioconversion technologies in the United States. Key uncertainties in the major processes: pre-treatment, hydrolysis, and fermentation are evaluated. The potential to reduce fossil energy use and greenhouse gas (GHG) emissions varies among bioconversion processes, although all options studied are considerably more attractive than gasoline. Anticipated future performance is found to be considerably more attractive than that published in the literature as being achieved to date. Electricity co-product credits are important in characterizing the GHG impacts of different ethanol production pathways; however, in the absence of near-term liquid transportation fuel alternatives to gasoline, optimizing ethanol facilities to produce ethanol (as opposed to co-products) is important for reducing the carbon intensity of the road transportation sector and for energy security.

'Capture ready' regulation of fossil fuel power plants - Betting the UK's carbon emissions on promises of future technology

International Nuclear Information System (INIS)

Markusson, Nils; Haszeldine, Stuart

2010-01-01

Climate change legislation requires emissions reductions, but the market shows interest in investing in new fossil fuelled power plants. The question is whether capture ready policy can reconcile these interests. The term 'capture ready' has been used a few years by the UK Government when granting licences for fossil fuelled power plants, but only recently has the meaning of the term been defined. The policy has been promoted as a step towards CCS and as an insurance against carbon lock-in. This paper draws on literature on technology lock-in and on regulation of technology undergoing development. Further, versions of the capture readiness concept proposed to date are compared. Capture readiness requirements beyond the minimum criterion of space on the site for capture operations are explored. This includes integration of capture and power plant, downstream operations, overall system integration and regulation of future retrofitting. Capture readiness comes with serious uncertainties and is no guarantee that new-built fossil plants will be abatable or abated in the future. As a regulatory strategy, it has been over-promised in the UK.

Digital technology and human development: A charter for nature conservation

NARCIS (Netherlands)

Maffey, G.; Homans, H.; Banks, K.; Arts, K.A.J.

2015-01-01

The application of digital technology in conservation holds much potential for advancing the understanding of, and facilitating interaction with, the natural world. In other sectors, digital technology has long been used to engage communities and share information. Human development—which holds

Biomass torrefaction: A promising pretreatment technology for biomass utilization

Science.gov (United States)

Chen, ZhiWen; Wang, Mingfeng; Ren, Yongzhi; Jiang, Enchen; Jiang, Yang; Li, Weizhen

2018-02-01

Torrefaction is an emerging technology also called mild pyrolysis, which has been explored for the pretreatment of biomass to make the biomass more favorable for further utilization. Dry torrefaction (DT) is a pretreatment of biomass in the absence of oxygen under atmospheric pressure and in a temperature range of 200-300 degrees C, while wet torrrefaction (WT) is a method in hydrothermal or hot and high pressure water at the tempertures within 180-260 degrees C. Torrrefied biomass is hydrophobic, with lower moisture contents, increased energy density and higher heating value, which are more comparable to the characteristics of coal. With the improvement in the properties, torrefied biomass mainly has three potential applications: combustion or co-firing, pelletization and gasification. Generally, the torrefaction technology can accelerate the development of biomass utilization technology and finally realize the maximum applications of biomass energy.

Allowance Holdings and Transfers Data Inventory

Data.gov (United States)

U.S. Environmental Protection Agency — The Allowance Holdings and Transfers Data Inventory contains measured data on holdings and transactions of allowances under the NOx Budget Trading Program (NBP), a...

12 CFR 1252.1 - Enterprise portfolio holding criteria.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Enterprise portfolio holding criteria. 1252.1 Section 1252.1 Banks and Banking FEDERAL HOUSING FINANCE AGENCY ENTERPRISES PORTFOLIO HOLDINGS § 1252.1 Enterprise portfolio holding criteria. The Enterprises are required to comply with the portfolio holdings...

12 CFR 225.124 - Foreign bank holding companies.

Science.gov (United States)

2010-01-01

... SYSTEM BANK HOLDING COMPANIES AND CHANGE IN BANK CONTROL (REGULATION Y) Regulations Financial Holding Companies Interpretations § 225.124 Foreign bank holding companies. (a) Effective December 1, 1971, the... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Foreign bank holding companies. 225.124 Section...

Excess cash holdings and shareholder value

OpenAIRE

Lee, Edward; Powell, Ronan

2011-01-01

We examine the determinants of corporate cash holdings in Australia and the impact on shareholder wealth of holding excess cash. Our results show that a trade-off model best explains the level of a firm’s cash holdings in Australia. We find that 'transitory' excess cash firms earn significantly higher risk-adjusted returns compared to 'persistent' excess cash firms, suggesting that the market penalises firms that hoard cash. The marginal value of cash also declines with larger cash balances, ...

12 CFR 575.14 - Subsidiary holding companies.

Science.gov (United States)

2010-01-01

... follows: Federal MHC Subsidiary Holding Company Charter Section 1. Corporate title. The full corporate... subsidiary holding company available for distribution, in cash or in kind. Each share of common stock shall... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Subsidiary holding companies. 575.14 Section...

The Scary Promise of Technology: Developing New Forms of Audience Research

NARCIS (Netherlands)

Dr. Joke Hermes

2012-01-01

The essays in this volume discuss both the culture of technology that we live in today, and culture as technology. Within the chapters of the book cultures of technology and cultural technologies are discussed, focussing on a variety of examples, from varied national contexts. The book brings

Sports-related lung injury during breath-hold diving

Directory of Open Access Journals (Sweden)

Tanja Mijacika

2016-12-01

Full Text Available The number of people practising recreational breath-hold diving is constantly growing, thereby increasing the need for knowledge of the acute and chronic effects such a sport could have on the health of participants. Breath-hold diving is potentially dangerous, mainly because of associated extreme environmental factors such as increased hydrostatic pressure, hypoxia, hypercapnia, hypothermia and strenuous exercise. In this article we focus on the effects of breath-hold diving on pulmonary function. Respiratory symptoms have been reported in almost 25% of breath-hold divers after repetitive diving sessions. Acutely, repetitive breath-hold diving may result in increased transpulmonary capillary pressure, leading to noncardiogenic oedema and/or alveolar haemorrhage. Furthermore, during a breath-hold dive, the chest and lungs are compressed by the increasing pressure of water. Rapid changes in lung air volume during descent or ascent can result in a lung injury known as pulmonary barotrauma. Factors that may influence individual susceptibility to breath-hold diving-induced lung injury range from underlying pulmonary or cardiac dysfunction to genetic predisposition. According to the available data, breath-holding does not result in chronic lung injury. However, studies of large populations of breath-hold divers are necessary to firmly exclude long-term lung damage.

49 CFR 178.338-9 - Holding time.

Science.gov (United States)

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Holding time. 178.338-9 Section 178.338-9... Specifications for Containers for Motor Vehicle Transportation § 178.338-9 Holding time. (a) “Holding time” is the time, as determined by testing, that will elapse from loading until the pressure of the contents...

Technology in Education: Its Prospects and Its Promises.

Science.gov (United States)

Senese, Donald J.

The impact of advanced technology has increased computer usage at all levels as evidenced by the popularity of video games, increased interest on the part of students using computers to enhance learning, and business/school partnerships forming with such companies as Digital Equipment Corporation, International Business Machines, and Tandy/Radio…

Are Some Technologies Beyond Regulatory Regimes?

Energy Technology Data Exchange (ETDEWEB)

Jones, Wendell B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kusnezov, Dimitri [National Nuclear Security Administration (NNSA), Washington, DC (United States)

2017-08-01

Regulatory frameworks are a common tool in governance to incent and coerce behaviors supporting national or strategic stability. This includes domestic regulations and international agreements. Though regulation is always a challenge, the domain of fast evolving threats, like cyber, are proving much more difficult to control. Many discussions are underway searching for approaches that can provide national security in these domains. We use game theoretic learning models to explore the question of strategic stability with respect to the democratization of certain technologies (such as cyber). We suggest that such many-player games could inherently be chaotic with no corresponding (Nash) equilibria. In the absence of such equilibria, traditional approaches, as measures to achieve levels of overall security, may not be suitable approaches to support strategic stability in these domains. Altogether new paradigms may be needed for these issues. At the very least, regulatory regimes that fail to address the basic nature of the technology domains should not be pursued as a default solution, regardless of success in other domains. In addition, the very chaotic nature of these domains may hold the promise of novel approaches to regulation.

Holdings of the Federal German Government in 1988

International Nuclear Information System (INIS)

1989-01-01

The report provides an overview of the direct and more important indirect holdings of the Federal German Government and its special assets ERP, Compensation Fund, Federal Mail and Federal Railway. Part A provides a total survey of the number of government holdings. For the direct holdings of the Federal Government and its special assets the shares in nominal capital and registered foundation capital, number of employees and dividend on profits are presented. In Parts B to M, the narrative parts, the most important holdings are reported on more in detail (sphere of activities, economic development, composition of the corporate bodies). The listing order does not reflect any order of importance. The following part N contains alphabetic indexes. Indexes I and II list all the direct holdings of the Federal Government and its special assets irrespective of the nominal capital volume and share of holdings. In index III, are listed only companies with corporate activites and a nominal capital of at least 100.000 German Marks of which the Federal Government and/or its special assets hold directly or indirectly at least 25 percent. Holdings of these undertakings of which the Federal Government does not have majority ownership, and which are not dependent on it under the regulations governing shareholdings either, are not considered. (orig.) [de

Breath-Holding Spells

Science.gov (United States)

... reviewed: October 2016 More on this topic for: Parents Is It Normal for Children to Hold Their Breath? Taming Tempers Disciplining Your Child Disciplining Your Toddler Temper Tantrums Separation Anxiety View more About Us Contact Us Partners ...

Fuzzy promises

DEFF Research Database (Denmark)

Anker, Thomas Boysen; Kappel, Klemens; Eadie, Douglas

2012-01-01

as narrative material to communicate self-identity. Finally, (c) we propose that brands deliver fuzzy experiential promises through effectively motivating consumers to adopt and play a social role implicitly suggested and facilitated by the brand. A promise is an inherently ethical concept and the article...... concludes with an in-depth discussion of fuzzy brand promises as two-way ethical commitments that put requirements on both brands and consumers....

Promise assessment: A corollary to risk assessment for characterizing benefits

International Nuclear Information System (INIS)

Sholtis, J.A. Jr.

1993-01-01

Decisions involving the use of hazardous technologies are often made based on risk-benefit considerations. This is the case for U.S. space mission use of nuclear power and propulsion systems, where launch decisions are made within the office of the President. A great deal of time and effort is spent characterizing the risk for each nuclear-powered space mission. However, this is not so for benefits, even though they are no less important. To correct this situation, a new technical term--promise--is defined, and a new methodology--promise assessment--is proposed. This paper introduces and advances this concept, addresses its future application, as a tool, can be developed sufficiently and applied to methodically identify and characterized benefits. Further, it can introduce a degree of balance when judgments concerning the use of hazardous technologies are involved

76 FR 20459 - Savings and Loan Holding Company Application

Science.gov (United States)

2011-04-12

... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Savings and Loan Holding Company... concerning the following information collection. Title of Proposal: Savings and Loan Holding Company... officer of a savings and loan holding company, or any individual who owns, controls, or holds with power...

Sonographic Examination of The Fetus Vis-à-Vis Shoulder Dystocia: A Vexing Promise.

Science.gov (United States)

Doty, Morgen S; Al-Hafez, Leen; Chauhan, Suneet P

2016-12-01

Since antepartum and intrapartum risk factors are poor at identifying women whose labor is complicated by shoulder dystocia, sonographic examination of the fetus holds promise. Though there are several measurements of biometric parameters to identify the parturient who will have shoulder dystocia, none are currently clinically useful. Three national guidelines confirm that sonographic measurements do not serve as appropriate diagnostic tests to identify women who will have shoulder dystocia with or without concurrent injury. In summary, biometric measurements of the fetus should not be used to alter clinical management with the aim of averting shoulder dystocia.

Blue breath holding is benign.

OpenAIRE

Stephenson, J B

1991-01-01

In their recent publication in this journal, Southall et al described typical cyanotic breath holding spells, both in otherwise healthy children and in those with brainstem lesions and other malformations. Their suggestions regarding possible autonomic disturbances may require further study, but they have adduced no scientific evidence to contradict the accepted view that in the intact child blue breath holding spells are benign. Those families in which an infant suffers an 'apparently life t...

Examination of the bases for proposed innovations in reactor safety technology

International Nuclear Information System (INIS)

Moses, D.L.

1986-01-01

This paper employs the criteria for evaluations from the Nuclear Power Option Viability Study to examine the bases for proposed innovations in light water reactor safety technology. These bases for innovation fall into four broad categories as follows: (1) virtually exclusive reliance on passive safety features to preclude core damage in all situations, (2) design simplification using some passive safety features to reduce the frequency of core damage to less than about 10 -6 per reactor-year, (3) passive containment to preclude releases from any accident, and (4) designing to limit licensing attention to one or at least a few systems. Of these, only the first two, and perhaps only the second, hold significant promise for providing for the viability of advanced light water reactors

The Determinants and Implications of Corporate Cash Holdings

OpenAIRE

Tim Opler; Lee Pinkowitz; Rene Stulz; Rohan Williamson

1997-01-01

We examine the determinants and implications of holdings of cash and marketable" securities by publicly traded U.S. firms in the 1971-1994 period. Firms with strong growth" opportunities and riskier cash flows hold relatively high ratios of cash to total assets. Firms" that have the greatest access to the capital markets (e.g. large firms and those with credit" ratings) tend to hold lower ratios of cash to total assets. These results are consistent with the" view that firms hold liquid assets...

12 CFR 583.20 - Savings and loan holding company.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Savings and loan holding company. 583.20... REGULATIONS AFFECTING SAVINGS AND LOAN HOLDING COMPANIES § 583.20 Savings and loan holding company. The term savings and loan holding company means any company that directly or indirectly controls a savings...

77 FR 58203 - AER Energy Resources, Inc.; Alto Group Holdings, Inc.; Bizrocket.Com Inc.; Fox Petroleum, Inc...

Science.gov (United States)

2012-09-19

... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] AER Energy Resources, Inc.; Alto Group Holdings, Inc.; Bizrocket.Com Inc.; Fox Petroleum, Inc.; Geopulse Explorations Inc.; Global Technologies... accuracy of press releases concerning the company's revenues. 4. Fox Petroleum, Inc. is a Nevada...

Superconducting radio frequency technology: Expanding the horizons of physics and technology

International Nuclear Information System (INIS)

Grunder, H.A.; Leemann, C.W.; Sundelin, R.M.; Hartline, B.K.

1986-01-01

This paper describes a major new technology supporting the further evolution of accelerators: superconducting radio frequency (SRF) technology, which is today on the verge of large-scale application in accelerators. Originally foreseen in the early 1960s as a promising technology, SRF only recently has overcome several technological and practical hurdles. SRF accelerating structures promise low rf losses and high gradients under cw operation. High-quality, intense cw beams can be accelerated without risk of melting the structure and without requiring enormous amounts of input rf power

Creditor rights, country governance, and corporate cash holdings

NARCIS (Netherlands)

Seifert, Bruce; Gonenc, Halit

2016-01-01

This study examines the impact of creditor rights and country governance on cash holdings using a sample of firms from 47 countries. We hypothesize that cash holdings are smaller when both creditor rights and country governance are high. In these circumstances firms will not need to hold as much

12 CFR 583.12 - Multiple savings and loan holding company.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Multiple savings and loan holding company. 583... DEFINITIONS FOR REGULATIONS AFFECTING SAVINGS AND LOAN HOLDING COMPANIES § 583.12 Multiple savings and loan holding company. The term multiple savings and loan holding company means any savings and loan holding...

12 CFR 583.11 - Diversified savings and loan holding company.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Diversified savings and loan holding company... DEFINITIONS FOR REGULATIONS AFFECTING SAVINGS AND LOAN HOLDING COMPANIES § 583.11 Diversified savings and loan holding company. The term diversified savings and loan holding company means any savings and loan holding...

12 CFR 225.81 - What is a financial holding company?

Science.gov (United States)

2010-01-01

... RESERVE SYSTEM BANK HOLDING COMPANIES AND CHANGE IN BANK CONTROL (REGULATION Y) Regulations Financial Holding Companies § 225.81 What is a financial holding company? (a) Definition. A financial holding... 12 Banks and Banking 3 2010-01-01 2010-01-01 false What is a financial holding company? 225.81...

MicroRNA: a new and promising potential biomarker for diagnosis and prognosis of ovarian cancer

International Nuclear Information System (INIS)

Pal, Manish K.; Jaiswar, Shyam P.; Dwivedi, Vinaya N.; Tripathi, Amit K.; Dwivedi, Ashish; Sankhwar, Pushplata

2015-01-01

Epithelial ovarian cancer (EOC) is the leading cause of death among all gynecological malignancies. Despite the technological and medical advances over the past four decades, such as the development of several biological markers (mRNA and proteins biomarkers), the mortality rate of ovarian cancer remains a challenge because of its late diagnosis, which is specifically attributed to low specificities and sensitivities. Under this compulsive scenario, recent advances in expression biology have shifted in identifying and developing specific and sensitive biomarkers, such as microRNAs (miRNAs) for cancer diagnosis and prognosis. MiRNAs are a novel class of small non-coding RNAs that deregulate gene expression at the posttranscriptional level, either by translational repression or by mRNA degradation. These mechanisms may be involved in a complex cascade of cellular events associated with the pathophysiology of many types of cancer. MiRNAs are easily detectable in tissue and blood samples of cancer patients. Therefore, miRNAs hold good promise as potential biomarkers in ovarian cancer. In this review, we attempted to provide a comprehensive profile of key miRNAs involved in ovarian carcinoma to establish miRNAs as more reliable non-invasive clinical biomarkers for early detection of ovarian cancer compared with protein and DNA biomarkers

Stem Cell Technology in Cardiac Regeneration: A Pluripotent Stem Cell Promise

OpenAIRE

Robin Duelen; Maurilio Sampaolesi

2017-01-01

Despite advances in cardiovascular biology and medical therapy, heart disorders are the leading cause of death worldwide. Cell-based regenerative therapies become a promising treatment for patients affected by heart failure, but also underline the need for reproducible results in preclinical and clinical studies for safety and efficacy. Enthusiasm has been tempered by poor engraftment, survival and differentiation of the injected adult stem cells. The crucial challenge is identification and s...

MFTF-progress and promise

International Nuclear Information System (INIS)

Thomassen, K.I.

1980-01-01

The Mirror Fusion Test Facility (MFTF) has been in construction at Lawrence Livermore National Laboratory (LLNL) for 3 years, and most of the major subsystems are nearing completion. Recently, the scope of this project was expanded to meet new objectives, principally to reach plasma conditions corresponding to energy break-even. To fulfill this promise, the single-cell minimum-B mirror configuration will be replaced with a tandem mirror configuration (MFTF-B). The facility must accordingly be expanded to accomodate the new geometry. This paper briefly discusses the status of the major MFTF subsystems and describes how most of the technological objectives of MFTF will be demonstrated before we install the additional systems necessary to make the tandem. It also summarizes the major features of the expanded facility

The National Artificial Intelligence Research And Development Strategic Plan

Data.gov (United States)

Networking and Information Technology Research and Development, Executive Office of the President — Executive Summary: Artificial intelligence (AI) is a transformative technology that holds promise for tremendous societal and economic benefit. AI has the potential...

Promising technology for the melting and decontamination of dismantled metal by an induction cold crucible

International Nuclear Information System (INIS)

Suzuki, M.; Tsurumaki, K.; Akiyama, T.; Fukumura, N.; Tanaka, T.; Yoshida, M.; Ikenaga, Y.

1998-01-01

An induction cold crucible melting is one of the most promising technology for the reuse and decontamination of the radioactively contaminated metallic materials generated during the dismantling of nuclear facilities, because the crucible ensures a long life operation without generating the secondary wastes. Based on the knowledge obtained through the fundamental study using the crucible of 45 mm in diameter, the MERC(Melting and Recycling of Metals by -Cold Crucible) process was designed, manufactured and scaled up to 100-140 mm in diameter. Not only cylindrical sectional crucibles but also rectangular slab sectional crucibles were developed. The maximum power of the high frequency generator is 150 kW and the frequency is 25 kHz. In the MERC, either fragments of stainless steel or tubing and pipings with small section, which were the surrogates of contaminated metallic materials, were continuously supplied together with the flux for the decontamination, followed by melting in the crucible and pulling down by the precise withdrawal system ensuring the melt dome to be kept at a suitable level for the melting. The maximal withdrawal velocity employed was 12 mm/min. The Ingot and slab were cut in every 300 mm length by the mechanical saw. They were automatically transported to the outlet of the equipment by the conveying system. Heat efficiency of the MERC was more than 26%. The ingot surface was smooth and crack free, facilitating the removal of radioactive elements concentrated in a slag stuck on the ingot surface. There was no macro segregation inside. Tracer elements of Sr and Hf transferred to the slag, Cs and Zn to the dust. Co and Mn mostly remained in the ingot. However, up to 10% of Co could transfer to the slag. This work was done under the sponsorship of Science and Technology Agency of Japan. (author)

Delivery of agricultural technology to resource-poor farmers in Africa.

Science.gov (United States)

Mignouna, Hodeba D; Abang, Mathew M; Omanya, Gospel; Nang'ayo, Francis; Bokanga, Mpoko; Boadi, Richard; Muchiri, Nancy; Terry, Eugene

2008-01-01

Recent developments in agricultural science and technology have the potential to transform the agricultural sector in the developing world. These technological advances constitute key drivers of economic growth and hold great promise for poverty reduction in sub-Saharan Africa (SSA). Agricultural research and development in Africa is undergoing a major paradigm shift. Until recently, public-sector institutions in Africa worked in isolation to create and disseminate agricultural technologies to smallholder farmers. However, they need access to improved proprietary technologies developed for the most part by the private sector in developed countries. These technologies are currently concentrated in the hands of a few large corporations and are protected by intellectual property rights. The African Agricultural Technology Foundation (AATF) is a new initiative addressing the challenges associated with the access, development, and deployment of agricultural technologies to smallholder farmers in SSA. This article describes the AATF model of facilitating the creation of partnership alliances dedicated to promote and support collaboration among a wide variety of public- and private-sector organizations around shared agricultural research and development goals for the public good. It explains AATF's public-private partnership framework for technology delivery in the light of market failures, institutional constraints, and systemic weaknesses, which impede public-sector organizations from accessing and delivering pro-poor knowledge and technology to farmers. The article provides policy makers, research managers, and business decision makers with an understanding of how access to, and delivery of, proprietary technologies could contribute to food security and the improvement of farmers' livelihoods in Africa.

Safety Assessment of Nanotechnology Products

Science.gov (United States)

Nanotechnology has important opportunities to affect technological challenges in such diverse areas as electronics, energy, water purification, food storage, and therapeutics. These emerging technologies hold great promise both for global economic growth and a sustainable environ...

The challenges of government use of cloud services for public service delivery

NARCIS (Netherlands)

Irion, K.

2014-01-01

Cloud services hold the promise of rendering public service delivery and back-office operations more effective and efficient, by providing ubiquitous, on-demand access to computing resources. Beyond the compelling cost economies, cloud technology is also a promising platform for open government,

Perpendicular recording: the promise and the problems

International Nuclear Information System (INIS)

Wood, Roger; Sonobe, Yoshiaki; Jin Zhen; Wilson, Bruce

2001-01-01

Perpendicular recording has long been advocated as a means of achieving the highest areal densities. In particular, in the context of the 'superparamagnetic limit', perpendicular recording with a soft underlayer promises several key advantages. These advantages include a higher coercivity, thicker media that should permit smaller diameter grains and higher signal-to-noise ratio. Also, the sharper edge-writing will facilitate recording at very high track densities (lower bit aspect ratio). Recent demonstrations of the technology have shown densities comparable with the highest densities reported for longitudinal recording. This paper further examines the promise that perpendicular recording will deliver an increase in areal density two to eight times higher than that achievable with longitudinal recording. There are a number of outstanding issues but the key challenge is to create a low-noise medium with a coercivity that is high and is much larger than the remanent magnetization

Oxyfuel technology with focus on the boiler

Energy Technology Data Exchange (ETDEWEB)

Kluger, Frank; Krohmer, Bernd; Moenckert, Patrick; Stamatelopoulos, Georg-Nikolaus [Alstom Power Systems GmbH (Germany)

2009-07-01

Against the background of a worldwide increasing use of fossil primary energy carriers for the power and heat generation and the associated impact of CO{sub 2} emissions on the climate, technologies for CO{sub 2} reduction or separation and storage for power plant processes (Carbon Capture and Storage = CCS) must be developed and brought to market within a short time. Considerable efforts for the development of CO{sub 2} separation technologies are undertaken both by the power plant operators and power plant manufacturers. Alstom develops technologies for CO{sub 2} separation, which can be integrated in new plants and with which existing power plants can also be retrofitted. For the power plant industry, the development of economic solutions for the existing power plant fleet holds as well the possibility of exploiting the maximum CO{sub 2} reduction potential once commercial introduction of these technologies has started. The ''oxyfuel'' technology is one of the most promising CO{sub 2} separation technologies in terms of performance, life cycle costs, and development time as a result of the adaptation of proven large scale industrial equipment, and it can be employed for both new plants and as retrofit for existing power plants. The different CO{sub 2} separation technologies are already partly tested on pilot plant scale and provide important knowledge for the design of demonstration plants, which must then also prove the economic efficiency of the relevant technology besides the technical feasibility. Alstom participates in various pilot projects (15 - 30 MW{sub th}) for the further development of the oxyfuel technology and is creating a broad knowledge base for the design, construction and operation of an oxyfuel demonstration power plant (200 - 300 MW{sub el}) and subsequent commercial deployment. (orig.)

Phase-Type Models of Channel-Holding Times in Cellular Communication Systems

DEFF Research Database (Denmark)

Christensen, Thomas Kaare; Nielsen, Bo Friis; Iversen, Villy Bæk

2004-01-01

In this paper, we derive the distribution of the channel-holding time when both cell-residence and call-holding times are phase-type distributed. Furthermore, the distribution of the number of handovers, the conditional channel-holding time distributions, and the channel-holding time when cell re...... residence times are correlated are derived. All distributions are of phase type, making them very general and flexible. The channel-holding times are of importance in performance evaluation and simulation of cellular mobile communication systems.......In this paper, we derive the distribution of the channel-holding time when both cell-residence and call-holding times are phase-type distributed. Furthermore, the distribution of the number of handovers, the conditional channel-holding time distributions, and the channel-holding time when cell...

Governance mechanisms, investment opportunity set and SMEs cash holdings

OpenAIRE

Belghitar, Yacine; Khan, James

2013-01-01

This study analyses the effect of firm characteristics and governance mechanisms on cash holdings for a sample of UK SMEs. The results show that UK SMEs with greater cash flow volatility and institutional investors hold more cash; whereas levered and dividend paying SMEs with non-executive ownership hold less cash. We also find that ownership structure is significant only in explaining the cash holdings for firms with high growth investment opportunities, and leverage is only significant in e...

Synthetic biology platform technologies for antimicrobial applications.

Science.gov (United States)

Braff, Dana; Shis, David; Collins, James J

2016-10-01

The growing prevalence of antibiotic resistance calls for new approaches in the development of antimicrobial therapeutics. Likewise, improved diagnostic measures are essential in guiding the application of targeted therapies and preventing the evolution of therapeutic resistance. Discovery platforms are also needed to form new treatment strategies and identify novel antimicrobial agents. By applying engineering principles to molecular biology, synthetic biologists have developed platforms that improve upon, supplement, and will perhaps supplant traditional broad-spectrum antibiotics. Efforts in engineering bacteriophages and synthetic probiotics demonstrate targeted antimicrobial approaches that can be fine-tuned using synthetic biology-derived principles. Further, the development of paper-based, cell-free expression systems holds promise in promoting the clinical translation of molecular biology tools for diagnostic purposes. In this review, we highlight emerging synthetic biology platform technologies that are geared toward the generation of new antimicrobial therapies, diagnostics, and discovery channels. Copyright © 2016 Elsevier B.V. All rights reserved.

75 FR 18482 - Environmental Technologies Trade Advisory Committee (ETTAC)

Science.gov (United States)

2010-04-12

... DEPARTMENT OF COMMERCE Environmental Technologies Trade Advisory Committee (ETTAC) AGENCY... Environmental Technologies Trade Advisory Committee (ETTAC) will hold its quarterly meeting to discuss environmental technologies trade liberalization, industry competitiveness issues, and general Committee...

Promising Practices: A Literature Review of Technology Use by Underserved Students

Science.gov (United States)

Zielezinski, Molly B.; Darling-Hammond, Linda

2016-01-01

How can technologies and digital learning experiences be used to support underserved, under-resourced, and underprepared students? For many years, educators, researchers, and policy makers looking for strategies to close the achievement gap and improve student learning have sought solutions involving new uses of technology, especially for students…

76 FR 35085 - Savings and Loan Holding Company Application

Science.gov (United States)

2011-06-15

... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Savings and Loan Holding Company... Proposal: Savings Loan Holding Company Application. OMB Number: 1550-0015. Form Numbers: H-(e). Description... that no company, or any director or officer of a savings and loan holding company, or any individual...

South African physicians’ acceptance of e-prescribing technology: an empirical test of a modified UTAUT model

Directory of Open Access Journals (Sweden)

Jason Cohen

2013-07-01

Full Text Available E-prescribing systems hold promise for improving the quality and efficiency of the scripting process. Yet, the use of the technology has been associated with a number of challenges. The diffusion of e-prescribing into physician practices and the consequent realisation of its potential benefits will depend on whether physicians are willing to accept and engage with the technology. This study draws on the Unified Theory of Acceptance and Use of Technology (UTAUT and recent literature on user trust in technology to develop and test a model of the factors influencing South African physicians’ acceptance of e-prescribing. Data was collected from a sample of 72 physicians. Results indicate a general acceptance of e-prescribing amongst physicians who on average reported strong intentions to use e-prescribing technologies if given the opportunity. PLS analysis revealed that physicians’ performance expectancies and perceptions of facilitating conditions had significant direct effects on acceptance whilst trust and effort expectancy had important indirect effects. Social influence and price value perceptions did not add additional explanatory power. The model explained 63% of the variation in physician acceptance.

76 FR 25732 - Order of Suspension of Trading; In the Matter of Advanced Refractive Technologies, Inc., Bluebook...

Science.gov (United States)

2011-05-05

... of Advanced Refractive Technologies, Inc., Bluebook International Holding Co. (The), CBCom, Inc., Gener8xion Entertainment, Inc., Group Long Distance Inc., HiEnergy Technologies, Inc., and Holter Technologies Holding, A.G. (n/k/a International Consortium Corp.) It appears to the Securities and Exchange...

75 FR 52716 - Environmental Technologies Trade Advisory Committee (ETTAC)

Science.gov (United States)

2010-08-27

... DEPARTMENT OF COMMERCE Environmental Technologies Trade Advisory Committee (ETTAC) AGENCY... Environmental Technologies Trade Advisory Committee (ETTAC) will hold its quarterly meeting to discuss environmental technologies industry competitiveness issues, the National Export Initiative, and general...

Emerging Cancer Vaccines: The Promise of Genetic Vectors

International Nuclear Information System (INIS)

Aurisicchio, Luigi; Ciliberto, Gennaro

2011-01-01

Therapeutic vaccination against cancer is an important approach which, when combined with other therapies, can improve long-term control of cancer. In fact, the induction of adaptive immune responses against Tumor Associated Antigens (TAAs) as well as innate immunity are important factors for tumor stabilization/eradication. A variety of immunization technologies have been explored in last decades and are currently under active evaluation, such as cell-based, protein, peptide and heat-shock protein-based cancer vaccines. Genetic vaccines are emerging as promising methodologies to elicit immune responses against a wide variety of antigens, including TAAs. Amongst these, Adenovirus (Ad)-based vectors show excellent immunogenicity profile and have achieved immunological proof of concept in humans. In vivo electroporation of plasmid DNA (DNA-EP) is also a desirable vaccine technology for cancer vaccines, as it is repeatable several times, a parameter required for the long-term maintenance of anti-tumor immunity. Recent findings show that combinations of different modalities of immunization (heterologous prime/boost) are able to induce superior immune reactions as compared to single-modality vaccines. In this review, we will discuss the challenges and requirements of emerging cancer vaccines, particularly focusing on the genetic cancer vaccines currently under active development and the promise shown by Ad and DNA-EP heterologous prime-boost

75 FR 1590 - Environmental Technologies Trade Advisory Committee (ETTAC)

Science.gov (United States)

2010-01-12

... DEPARTMENT OF COMMERCE Environmental Technologies Trade Advisory Committee (ETTAC) AGENCY... Environmental Technologies Trade Advisory Committee (ETTAC) will hold its first plenary meeting of 2010 to discuss environmental technologies trade liberalization, industry competitiveness issues, and general...

Examining Preservice Elementary Teachers' Technology Self-Efficacy: Impact of Mobile Technology-Based Physics Curriculum

Science.gov (United States)

Menon, Deepika; Chandrasekhar, Meera; Kosztin, Dorina; Steinhoff, Douglas

2017-01-01

While iPads and other mobile devices are gaining popularity in educational settings, challenges associated with teachers' use of technology continue to hold true. Preparing preservice teachers within teacher preparation programs to gain experience learning and teaching science using mobile technologies is critical for them to develop positive…

Nanomedicine: Promising Tiny Machine for the Healthcare in Future-A Review

OpenAIRE

Saha, Moni

2009-01-01

One of the 21st century’s most promising technologies is nanotechnology. Nanomedicine, an offshoot of nanotechnology, refers to highly specific medical intervention at the molecular scale for curing disease or repairing damaged tissues, such as bone, muscle, or nerve. Nanotechnology is a collective term referring to technological developments on the nanometer scale, usually 0.1-100 nm. A nanometer is one-billionth of a meter, too small to be seen with a conventional laboratory microscope. It ...

Membrane-based processes for wastewater nutrient recovery: Technology, challenges, and future direction.

Science.gov (United States)

Xie, Ming; Shon, Ho Kyong; Gray, Stephen R; Elimelech, Menachem

2016-02-01

Wastewater nutrient recovery holds promise for more sustainable water and agricultural industries. We critically review three emerging membrane processes - forward osmosis (FO), membrane distillation (MD) and electrodialysis (ED) - that can advance wastewater nutrient recovery. Challenges associated with wastewater nutrient recovery were identified. The advantages and challenges of applying FO, MD, and ED technologies to wastewater nutrient recovery are discussed, and directions for future research and development are identified. Emphasis is given to exploration of the unique mass transfer properties of these membrane processes in the context of wastewater nutrient recovery. We highlight that hybridising these membrane processes with existing nutrient precipitation process will lead to better management of and more diverse pathways for near complete nutrient recovery in wastewater treatment facilities. Copyright © 2015 Elsevier Ltd. All rights reserved.

"Hold Harmless" Option for Staff Babysitting and Employee References

Science.gov (United States)

Bruno, Holly Elissa

2010-01-01

Help for educators and administrators may be on the way in the form of "hold harmless" documents that allow for flexibility in enforcing program policies. Having a "No Babysitting policy," and "Hold Harmless" documentation will not stop one's program from being sued. However, with the "No Babysitting policy" and "Hold Harmless" documentation…

Efficacy of computer technology-based HIV prevention interventions: a meta-analysis.

Science.gov (United States)

Noar, Seth M; Black, Hulda G; Pierce, Larson B

2009-01-02

To conduct a meta-analysis of computer technology-based HIV prevention behavioral interventions aimed at increasing condom use among a variety of at-risk populations. Systematic review and meta-analysis of existing published and unpublished studies testing computer-based interventions. Meta-analytic techniques were used to compute and aggregate effect sizes for 12 randomized controlled trials that met inclusion criteria. Variables that had the potential to moderate intervention efficacy were also tested. The overall mean weighted effect size for condom use was d = 0.259 (95% confidence interval = 0.201, 0.317; Z = 8.74, P partners, and incident sexually transmitted diseases. In addition, interventions were significantly more efficacious when they were directed at men or women (versus mixed sex groups), utilized individualized tailoring, used a Stages of Change model, and had more intervention sessions. Computer technology-based HIV prevention interventions have similar efficacy to more traditional human-delivered interventions. Given their low cost to deliver, ability to customize intervention content, and flexible dissemination channels, they hold much promise for the future of HIV prevention.

Promising Technologies of Mining and Processing of Solid Minerals

Science.gov (United States)

Shabaev, Sergey; Ivanov, Seregey; Vakhianov, Evgeniy

2017-11-01

The continuing growth in mineral extraction entails an increase in industrial waste, which in turn has a negative impact on the environment. Rubber-tired vehicles, in which the tires wear colossally, is mainly used as a transport for loading, unloading, transportation and other types of work in the extraction of solid minerals. The used tires are not disposed in any way, but are stored in special areas where harmful toxic substances are emitted under the influence of ultraviolet rays. Therefore, a decision was made to find a method for utilization and rational use of industrial waste in the road construction sector. The operating temperature of composite rubber-bituminous binders based on rubber crumb from the used automobile tires is estimated in this paper, which is necessary for assigning technological parameters of production and laying of asphalt-concrete mixtures produced on their basis. It is established that composite rubber-bituminous binders based on rubber chips from the used automobile tires, produced according to the two-stage technology, have the same viscosity as the original petroleum bitumen, at a temperature increased by 20°C.

The Parent Control in the Mechanical Engineering Management-Holding

Science.gov (United States)

Šnircová, Jana; Hodulíková, Petra; Joehnk, Peter

2012-12-01

The group of entities under the control of parent, so called holding, is arisen as the result and the most often used form of the business concentration nowadays. The paper is focused to find special tasks of parent company for to preserve effective unified economic control in the management-holding. The unified economic control the holding exists in the conditions of the main conflict of interest - holding is not a legal but economic unit and the connected companies into it have a legal autonomy with the economic dependence. The unified economic control limits the financial independence of every individual company of the holding. The attention in the paper is concentrated to the management concept of the parent control, i.e. the parent company supervises the control of intragroup flows and all of subsidiaries production activities.

PENGARUH KUALITAS AKRUAL DAN LEVERAGE TERHADAP CASH HOLDING PERUSAHAAN

Directory of Open Access Journals (Sweden)

Anggita Langgeng Wijaya

2010-12-01

Full Text Available This research tests the effect of accrual quality and leverage on corporate cash holding for a sample of manufacturing company listed in Indonesian Stock Exchange over the period 2006-2007. This research also tests the role of asymmetric information as a mediating variable on the relation between accrual quality and cash holding. Population of this research is 197 manufacturing companies at the Indonesian Stock Exchange. This research uses the purposive sampling method. Hypothesis test of this research em­ploys multiple regression analysis and path analysis. The results show that: accrual quality does not affect asymmetric information; asymmetric information positively affects corporate cash holdings; asymmetric information is not a mediating variable on the relation between accrual quality and cash holding; leverage negatively affects corporate cash holding.

Considerations for Realizing the Promise of Educational Gaming Technology

Science.gov (United States)

Nelson, Nancy J.; Fien, Hank; Doabler, Christian T.; Clarke, Ben

2016-01-01

One can barely keep up with the pace at which new educational games and apps are being introduced and digested in the market. With so many choices available, how do schools and teachers decide what to use? How do they have confidence their choices will result in desired outcomes? Education technology offers a number of potential benefits that can…

Korean Investment in EU through Holding Companies: A Case Study

Directory of Open Access Journals (Sweden)

Seong-Bong Lee

1998-09-01

Full Text Available When transnational enterprises set subsidiary companies in certain area, their major aim is to invest indirectly through the holding companies which hold invested share. Especially, because of the geographical neighborhood and economic integration, investing by holding companies is common in Europe. In Europe, taking full advantage of holding company is out of the following two reasons. Firstly, the efficiency and flexibility of the manage strategy of a group could be elevated by making full use of the holding company. Secondly, the transnational enterprises have the possibility of flexible management at the tax strategy level. Recently, the Korean companies are making the best use of holding companies when they are Marching into the EU. In the year 1996, group K purchased 8 enterprises of a certain industry section of B, a German company, setting holding companies in Germany. The analysis result of the case shows that the manage efficiency could be risen and the taxation could be reduced by way of making use of holding companies. As to the Korean investment efficiency of overseas indirect investment in EU, this thesis brought forward a blueprint about integrating the local companies.

Rock Equity Holdings, LLC

Science.gov (United States)

The EPA is providing notice of an Administrative Penalty Assessment in the form of an Expedited Storm Water Settlement Agreement against Rock Equity Holdings, LLC, for alleged violations at The Cove at Kettlestone/98th Street Reconstruction located at 3015

NextGen Flight Deck Surface Trajectory-Based Operations (STBO): Contingency Holds

Science.gov (United States)

Bakowski, Deborah Lee; Hooey, Becky Lee; Foyle, David C.; Wolter, Cynthia A.; Cheng, Lara W. S.

2013-01-01

The purpose of this pilot-in-the-loop taxi simulation was to investigate a NextGen Surface Trajectory-Based Operations (STBO) concept called "contingency holds." The contingency-hold concept parses a taxi route into segments, allowing an air traffic control (ATC) surface traffic management (STM) system to hold an aircraft when necessary for safety. Under nominal conditions, if the intersection or active runway crossing is clear, the hold is removed, allowing the aircraft to continue taxiing without slowing, thus improving taxi efficiency, while minimizing the excessive brake use, fuel burn, and emissions associated with stop-and-go taxi. However, when a potential traffic conflict exists, the hold remains in place as a fail-safe mechanism. In this departure operations simulation, the taxi clearance included a required time of arrival (RTA) to a specified intersection. The flight deck was equipped with speed-guidance avionics to aid the pilot in safely meeting the RTA. On two trials, the contingency hold was not released, and pilots were required to stop. On two trials the contingency hold was released 15 sec prior to the RTA, and on two trials the contingency hold was released 30 sec prior to the RTA. When the hold remained in place, all pilots complied with the hold. Results also showed that when the hold was released at 15-sec or 30-sec prior to the RTA, the 30-sec release allowed pilots to maintain nominal taxi speed, thus supporting continuous traffic flow; whereas, the 15-sec release did not. The contingency-hold concept, with at least a 30-sec release, allows pilots to improve taxiing efficiency by reducing braking, slowing, and stopping, but still maintains safety in that no pilots "busted" the clearance holds. Overall, the evidence suggests that the contingency-hold concept is a viable concept for optimizing efficiency while maintaining safety.

Augmented Reality Based Doppler Lidar Data Visualization: Promises and Challenges

Directory of Open Access Journals (Sweden)

Cherukuru N. W.

2016-01-01

As a proof of concept, we used the lidar data from a recent field campaign and developed a smartphone application to view the lidar scan in augmented reality. In this paper, we give a brief methodology of this feasibility study, present the challenges and promises of using AR technology in conjunction with Doppler wind lidars.

The water holding capacity of bark in Danish angiosperm trees

DEFF Research Database (Denmark)

Larsen, Hanne Marie Ellegård; Rasmussen, Hanne Nina; Nord-Larsen, Thomas

The water holding capacity of bark in seven Danish angiosperm trees was examined. The aim of the study was (1) to examine height trends and (2) bark thickness trends in relation to the water holding capacity and (3) to determine interspecific differences. The wet-weight and dry-weight of a total...... number of 427 bark samples were measured. The water holding capacity was calculated as the difference between wet-weight and dry-weight per wet-weight. The water holding capacity increased with elevation in most tree species and contrary to the expectation, thinner bark generally had a higher water...... holding capacity. Differences in the water holding capacity of bark may influence the occurrence and distribution of a wide range of bark-living organisms including the distribution of corticolous lichens....

SU-E-J-62: Breath Hold for Left-Sided Breast Cancer: Visually Monitored Deep Inspiration Breath Hold Amplitude Evaluated Using Real-Time Position Management

Energy Technology Data Exchange (ETDEWEB)

Conroy, L; Quirk, S; Smith, WL [The University of Calgary, Calgary, AB (Canada); Tom Baker Cancer Centre, Calgary, AB (Canada); Yeung, R; Phan, T [The University of Calgary, Calgary, AB (Canada); Hudson, A [Tom Baker Cancer Centre, Calgary, AB (Canada)

2015-06-15

Purpose: We used Real-Time Position Management (RPM) to evaluate breath hold amplitude and variability when gating with a visually monitored deep inspiration breath hold technique (VM-DIBH) with retrospective cine image chest wall position verification. Methods: Ten patients with left-sided breast cancer were treated using VM-DIBH. Respiratory motion was passively collected once weekly using RPM with the marker block positioned at the xiphoid process. Cine images on the tangent medial field were acquired on fractions with RPM monitoring for retrospective verification of chest wall position during breath hold. The amplitude and duration of all breath holds on which treatment beams were delivered were extracted from the RPM traces. Breath hold position coverage was evaluated for symmetric RPM gating windows from ± 1 to 5 mm centered on the average breath hold amplitude of the first measured fraction as a baseline. Results: The average (range) breath hold amplitude and duration was 18 mm (3–36 mm) and 19 s (7–34 s). The average (range) of amplitude standard deviation per patient over all breath holds was 2.7 mm (1.2–5.7 mm). With the largest allowable RPM gating window (± 5 mm), 4 of 10 VM-DIBH patients would have had ≥ 10% of their breath hold positions excluded by RPM. Cine verification of the chest wall position during the medial tangent field showed that the chest wall was greater than 5 mm from the baseline in only 1 out of 4 excluded patients. Cine images verify the chest wall/breast position only, whether this variation is acceptable in terms of heart sparing is a subject of future investigation. Conclusion: VM-DIBH allows for greater breath hold amplitude variability than using a 5 mm gating window with RPM, while maintaining chest wall positioning accuracy within 5 mm for the majority of patients.

Descriptors of Modular Formation of Accounting and Analytical Cluster in Innovation Development of Agricultural Holdings

Directory of Open Access Journals (Sweden)

Zhanna Degaltseva

2015-11-01

Full Text Available In the context of the division of accounting into financial accounting, taxation accounting, management accounting and statistical accounting a problem of improving their relationship arises. The accounting and analytical cluster plays the role of the correlating factor of the relationship between the subdivisions of the agricultural holding property. To improve its work a modular principle of its building based on information technology was introduced. Practical implementation of modular accounting and analytical cluster revealed its shortcomings. They were as follows: each type of account and each production unit used its own natural and cost parameters. The number and nature of these parameters were different. To eliminate the shortcomings in the information security of managers and specialists of the agricultural holding, we attempt to develop a methodology for establishing a rational number of descriptors (binding parameters for each module. The proposed descriptors are designed on the basis of validity of the methodological approach to their calculations and legal support. The proposed method allowed to limit the asymmetric information in all kinds of records, to improve its quality and to bring a synergistic effect from the scale and structure of the use of the agricultural holdings property complex.

Cash Holdings and Mutual Fund Performance

OpenAIRE

Mikhail Simutin

2014-01-01

Cash holdings of equity mutual funds impose a drag on fund performance but also allow managers to make quick investments in attractive stocks and satisfy outflows without costly fire sales. This article shows that actively managed equity funds with high abnormal cash—that is, with cash holdings in excess of the level predicted by fund attributes—outperform their low abnormal cash peers by over 2% per year. Managers carrying high abnormal cash compensate for the low return on cash by making su...

Looking Back and Looking Forward: Reprising the Promise and Predicting the Future of Formation Flying and Spaceborne GPS Navigation Systems

Science.gov (United States)

Bauer, Frank H.; Dennehy, Neil

2015-01-01

A retrospective consideration of two 15-year old Guidance, Navigation and Control (GN&C) technology 'vision' predictions will be the focus of this paper. A look back analysis and critique of these late 1990s technology roadmaps out-lining the future vision, for two then nascent, but rapidly emerging, GN&C technologies will be performed. Specifically, these two GN&C technologies were: 1) multi-spacecraft formation flying and 2) the spaceborne use and exploitation of global positioning system (GPS) signals to enable formation flying. This paper reprises the promise of formation flying and spaceborne GPS as depicted in the cited 1999 and 1998 papers. It will discuss what happened to cause that promise to be mostly unfulfilled and the reasons why the envisioned formation flying dream has yet to become a reality. The recent technology trends over the past few years will then be identified and a renewed government interest in spacecraft formation flying/cluster flight will be highlighted. The authors will conclude with a reality-tempered perspective, 15 years after the initial technology roadmaps were published, predicting a promising future of spacecraft formation flying technology development over the next decade.

Promising Technologies of Mining and Processing of Solid Minerals

Directory of Open Access Journals (Sweden)

Shabaev Sergey

2017-01-01

Full Text Available The continuing growth in mineral extraction entails an increase in industrial waste, which in turn has a negative impact on the environment. Rubber-tired vehicles, in which the tires wear colossally, is mainly used as a transport for loading, unloading, transportation and other types of work in the extraction of solid minerals. The used tires are not disposed in any way, but are stored in special areas where harmful toxic substances are emitted under the influence of ultraviolet rays. Therefore, a decision was made to find a method for utilization and rational use of industrial waste in the road construction sector. The operating temperature of composite rubber-bituminous binders based on rubber crumb from the used automobile tires is estimated in this paper, which is necessary for assigning technological parameters of production and laying of asphalt-concrete mixtures produced on their basis. It is established that composite rubber-bituminous binders based on rubber chips from the used automobile tires, produced according to the two-stage technology, have the same viscosity as the original petroleum bitumen, at a temperature increased by 20°C.

12 CFR Appendix E to Part 360 - Hold File Structure

Science.gov (United States)

2010-01-01

... ReasonReason for the hold. Possible values are: Character (2). • LN = Loan Collateral Hold • LG = Court... structure of the data file to provide information to the FDIC for each legal or collateral hold placed on a...

Electron-processing technology: A promising application for the viscose industry

Science.gov (United States)

Stepanik, T. M.; Rajagopal, S.; Ewing, D.; Whitehouse, R.

1998-06-01

In marketing its IMPELA ® line of high power, high-throughput industrial accelerators, Atomic Energy of Canada Limited (AECL) is working with viscose (rayon) companies world-wide to integrate electron-processing technology as part of the viscose manufacturing process. The viscose industry converts cellulose wood pulp into products such as staple fiber, filament, cord, film, packaging, and non-edible sausage casings. This multibillion dollar industry is currently suffering from high production costs, and is facing increasingly stringent environmental regulations. The use of electron-treated pulp can significantly lower production costs and can provide equally significant environmental benefits. This paper describes our current understanding of the benefits of using electron-treated pulp in this process, and AECL's efforts in developing this technology.

Multiple job holding, local labor markets, and the business cycle

Directory of Open Access Journals (Sweden)

Barry T. Hirsch

2016-04-01

Full Text Available Abstract About 5 % of US workers hold multiple jobs, which can exacerbate or mitigate employment changes over the business cycle. Theory is ambiguous and prior literature is not fully conclusive. We examine the relationship between multiple job holding and local unemployment rates using a large Current Population Survey data set of workers in urban labor markets during 1998–2013. Labor markets with high unemployment have moderately lower rates of multiple job holding. Yet no relationship between multiple job holding and unemployment is found within markets over time, with near-zero estimates being precisely estimated. Multiple job holding is largely acyclic. JEL Classification: J21

Automated Inventory Control System for Nigeria Power Holding

African Journals Online (AJOL)

PROF. O. E. OSUAGWU

2013-09-01

Sep 1, 2013 ... Power Holding Company of Nigeria (PHCN) currently holds in excess of millions in spare parts inventory ... equipment/utilities at all times in view of stochastic item ... line contingency and small conductor sizing lines which are ...

Do promises matter? An exploration of the role of promises in psychological contract breach.

Science.gov (United States)

Montes, Samantha D; Zweig, David

2009-09-01

Promises are positioned centrally in the study of psychological contract breach and are argued to distinguish psychological contracts from related constructs, such as employee expectations. However, because the effects of promises and delivered inducements are confounded in most research, the role of promises in perceptions of, and reactions to, breach remains unclear. If promises are not an important determinant of employee perceptions, emotions, and behavioral intentions, this would suggest that the psychological contract breach construct might lack utility. To assess the unique role of promises, the authors manipulated promises and delivered inducements separately in hypothetical scenarios in Studies 1 (558 undergraduates) and 2 (441 employees), and they measured them separately (longitudinally) in Study 3 (383 employees). The authors' results indicate that breach perceptions do not represent a discrepancy between what employees believe they were promised and were given. In fact, breach perceptions can exist in the absence of promises. Further, promises play a negligible role in predicting feelings of violation and behavioral intentions. Contrary to the extant literature, the authors' findings suggest that promises may matter little; employees are concerned primarily with what the organization delivers.

Cash Holdings Policy: a Dynamic Analysis of Brazilian Companies

Directory of Open Access Journals (Sweden)

Fadwa Muhieddine Dahrouge

2013-09-01

Full Text Available This paper investigates how corporate cash holdings were adjusted over time for Brazilian companies during the crisis of 2008-2009. We adopt a dynamic model of corporate cash holdings to evaluate the main determinants for the speed of adjustment of cash holdings at the optimum level. We find evidence that: a the adjustment costs of Brazilian companies are high implying a delay in reaching the optimum level of cash; b the low speed adjustment to the optimum level is due to the limited availability of credit and the high cost of bank debt; c during crisis, the changes in working capital are positively related to the level of cash holdings providing evidence that companies prefer finance to growth with liquidity; d companies have looked for long-term financing to secure liquidity rather than investing on fixed assets, implying a negative relationship between investment and cash holding.

Technology Specialisation 1, 2 & 3 Compendium

DEFF Research Database (Denmark)

Tambo, Torben; Koch, Christian; Hansen, Hans Henrik

2010-01-01

and progressive move forward inspired by the spirit of engineering. This compendium gives broad information on many aspects of the Technology Specialisation project courses relating to aim, method, mentor company roles, individual versus group performance, scientific motivation and many other issues. The content......Within the Master of Science in Technology-based Business Development study program, Technology Specialisations are the recurring technological stronghold. The Technology Specialisations should hold the students focus on the technological platform of this program and ideally constitute a continuous...

Slash-and-char: An ancient agricultural technique holds new promise for management of soils contaminated by Cd, Pb and Zn

International Nuclear Information System (INIS)

Niu, Li-qin; Jia, Pu; Li, Shao-peng; Kuang, Jia-liang; He, Xiao-xin; Zhou, Wen-hua; Liao, Bin; Shu, Wen-sheng; Li, Jin-tian

2015-01-01

Heavy metal contamination of agricultural soils is of worldwide concern. Unfortunately, there are currently no efficient and sustainable approaches for addressing this concern. In this study, we conducted a field experiment in which an agricultural soil highly contaminated by cadmium (Cd), lead (Pb) and zinc (Zn) was treated on-site by an ancient agricultural technique, ‘slash-and-char’, that was able to convert the biomass feedstock (rice straw) into biochar in only one day. We found evidence that in comparison to the untreated soil, the treated soil was associated with decreased bioavailability of the heavy metals and increased vegetable yields. Most importantly, the treatment was also coupled with dramatic reductions in concentrations of the heavy metals in vegetables, which made it possible to produce safe crops in this highly contaminated soil. Collectively, our results support the idea that slash-and-char offers new promise for management of soils contaminated by Cd, Pb and Zn. - Highlights: • We explored the potential of slash-and-char in dealing with soil metal pollution. • Metal bioavailability in the soil treated with slash-and-char was reduced by 24–65%. • Vegetable yield in the soil treated with slash-and-char was increased by 34–67%. • Slash-and-char could reduce the metal concentration in vegetables to a safe level. - An ancient agricultural technique called ‘slash-and-char’ offers new promise for management of soils contaminated multiply by Cd, Pb and Zn

Promises in intelligent plant control systems

International Nuclear Information System (INIS)

Otaduy, P.J.

1987-01-01

The control system is the brain of a power plant. The traditional goal of control systems has been productivity. However, in nuclear power plants the potential for disaster requires safety to be the dominant concern, and the worldwide political climate demands trustworthiness for nuclear power plants. To keep nuclear generation as a viable option for power in the future, trust is the essential critical goal which encompasses all others. In most of today's nuclear plants the control system is a hybrid of analog, digital, and human components that focuses on productivity and operates under the protective umbrella of an independent engineered safety system. Operation of the plant is complex, and frequent challenges to the safety system occur which impact on their trustworthiness. Advances in nuclear reactor design, computer sciences, and control theory, and in related technological areas such as electronics and communications as well as in data storage, retrieval, display, and analysis have opened a promise for control systems with more acceptable human brain-like capabilities to pursue the required goals. This paper elaborates on the promise of futuristic nuclear power plants with intelligent control systems and addresses design requirements and implementation approaches

Does imminent threat capture and hold attention?

Science.gov (United States)

Koster, Ernst H W; Crombez, Geert; Van Damme, Stefaan; Verschuere, Bruno; De Houwer, Jan

2004-09-01

According to models of attention and emotion, threat captures and holds attention. In behavioral tasks, robust evidence has been found for attentional holding but not for attentional capture by threat. An important explanation for the absence of attentional capture effects is that the visual stimuli used posed no genuine threat. The present study investigated whether visual cues that signal an aversive white noise can elicit attentional capture and holding effects. Cues presented in an attentional task were simultaneously provided with a threat value through an aversive conditioning procedure. Response latencies showed that threatening cues captured and held attention. These results support recent views on attention to threat, proposing that imminent threat captures attention in everyone. (c) 2004 APA, all rights reserved

26 CFR 1.552-1 - Definition of foreign personal holding company.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Definition of foreign personal holding company. 1...) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Foreign Personal Holding Companies § 1.552-1 Definition of foreign personal holding company. (a) A foreign personal holding company is any foreign...

Internet MEMS design tools based on component technology

Science.gov (United States)

Brueck, Rainer; Schumer, Christian

1999-03-01

The micro electromechanical systems (MEMS) industry in Europe is characterized by small and medium sized enterprises specialized on products to solve problems in specific domains like medicine, automotive sensor technology, etc. In this field of business the technology driven design approach known from micro electronics is not appropriate. Instead each design problem aims at its own, specific technology to be used for the solution. The variety of technologies at hand, like Si-surface, Si-bulk, LIGA, laser, precision engineering requires a huge set of different design tools to be available. No single SME can afford to hold licenses for all these tools. This calls for a new and flexible way of designing, implementing and distributing design software. The Internet provides a flexible manner of offering software access along with methodologies of flexible licensing e.g. on a pay-per-use basis. New communication technologies like ADSL, TV cable of satellites as carriers promise to offer a bandwidth sufficient even for interactive tools with graphical interfaces in the near future. INTERLIDO is an experimental tool suite for process specification and layout verification for lithography based MEMS technologies to be accessed via the Internet. The first version provides a Java implementation even including a graphical editor for process specification. Currently, a new version is brought into operation that is based on JavaBeans component technology. JavaBeans offers the possibility to realize independent interactive design assistants, like a design rule checking assistants, a process consistency checking assistants, a technology definition assistants, a graphical editor assistants, etc. that may reside distributed over the Internet, communicating via Internet protocols. Each potential user thus is able to configure his own dedicated version of a design tool set dedicated to the requirements of the current problem to be solved.

The application of microfluidic-based technologies in the cycle of metabolic engineering

Directory of Open Access Journals (Sweden)

Xiaoyan Ma

2016-09-01

Full Text Available The process of metabolic engineering consists of multiple cycles of design, build, test and learn, which is typically laborious and time-consuming. To increase the efficiency and the rate of success of strain engineering, novel instrumentation must be applied. Microfluidics, the control of liquid flow in microstructures, has enabled flexible, accurate, automatic, and high-throughput manipulation of cells in liquid at picoliter to nanoliter scale. These attributes hold great promise in advancing metabolic engineering in terms of the phases of design, build, test and learn. To promote the application of microfluidic-based technologies in strain improvement, this review addressed the potentials of microfluidics and the related approaches in DNA assembly, transformation, strain screening, genotyping and phenotyping, and highlighted their adaptations for single-cell analysis. As a result, this facilitates in-depth understanding of the metabolic network, which in turn promote efficient optimization in the following cycles of strain engineering. Taken together, microfluidic-based technologies enable on-chip workflow, and could greatly accelerate the turnaround of metabolic engineering.

Corporate Governance, Cash Holdings, and Firm Value: Evidence from Japan

OpenAIRE

Qi Luo; Toyohiko Hachiya

2005-01-01

This paper presents evidence on cash holdings for Japanese firms listed on the Tokyo Stock Exchange, focusing on the impact of corporate governance factors in cash holdings and the implication of cash holdings to firm value. We find that insider ownership and bank relations of firms play a significant role in determining cash holdings. Our results indicate that foreign stockholders select profitable firms to invest, and these firms have higher levels of cash. We document evidence that cash ho...

US/Japan workshop on mitigation and adaptation technologies related to global climate change

Energy Technology Data Exchange (ETDEWEB)

Bernthal, F.M.

1993-12-31

It is a great pleasure for me to have the honor of delivering the keynote address for this important gathering, an honor enhanced further because of the many activities and historic relationships represented by this workshop. First of all, it represents the spirit of continuing cooperation and good relations between the United States and Japan. With the aid of the framework provided by the U.S./Japan Science and Technology Agreement, our two nations can come together to address a problem that has no national boundaries {hor_ellipsis} and we can think about solutions of potential benefit to all citizens of the global community. This workshop also symbolizes the spirit of cooperation so characteristic of the conduct of research in science and technology -- cooperation between us as individual scientists and engineers, between the various institutions we represent, and across our diverse disciplines. This workshop is only the second of its kind. The first US/Japan Workshop on global climate change was held last year in Japan. That workshop focused on cooperative scientific research in the United States and Japan. Out of it came a general agreement to continue collaborative work and to extend cooperation into the area of global change-related technologies, in particular those technologies that hold promise for mitigation and adaptation.

Cembrit Holding A/S: At the crossroads

DEFF Research Database (Denmark)

Turcan, Romeo V.

2017-01-01

This is a Teaching Note (product number: 8B17M008) for the "Cembrit Holding A/S: At the crossroads" case (product number - 9B17M008) published by Ivey Publishing.......This is a Teaching Note (product number: 8B17M008) for the "Cembrit Holding A/S: At the crossroads" case (product number - 9B17M008) published by Ivey Publishing....

An Advanced Light Weight Recuperator for Space Power Systems, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — Nuclear Electric Propulsion (NEP) technology holds great promise for power and propulsion demands of NASA current and future deep space explorations. Closed Brayton...

Patent holdings of US biotherapeutic companies in major markets.

Science.gov (United States)

Sebastian, Teena E; Yerram, Chandra Bindu; Saberwal, Gayatri

2009-05-01

In previous studies we examined the (United States, US) patent holdings of 109 largely North American biotech companies developing therapeutics that, in particular, have an interest in discovery stage science. There appears little correlation between the number of patents and the number of products of individual companies. Here we quantified and compared the 103 US-headquartered companies' patent holdings in Australia, Canada, Europe, Japan and the US. The companies demonstrate variable and surprising patterns of patent holdings across these countries or regions. For most companies, patent holdings are not in proportion to the importance of the country as a biotech or pharma market. These results have implications for the patenting strategies of small biotech companies involved in drug discovery.

Technological advances in the treatment of trauma: a review of promising practices.

Science.gov (United States)

Paul, Lisa A; Hassija, Christina M; Clapp, Joshua D

2012-11-01

Given the availability of empirically supported practices for addressing posttraumatic stress disorder and other forms of trauma-related distress, the development and implementation of new technology to deliver these treatments is exciting. Technological innovations in this literature aim to expand availability of empirically based intervention, increase treatment adherence and acceptability, and overcome barriers commonly encountered with conventional trauma-focused treatment. Much of the current research on these technological developments consists of brief reviews and case studies of the separate therapy modalities. Although this work serves to document the appeal and utility of these innovations, it does not provide comprehensive information about the host of options available. To that end, the three general categories of technological advances in trauma therapy (i.e., videoconferencing, e-Health, virtual reality) are reviewed here, including information regarding their empirical support and suggestions for future research and clinical practice.

The promise of e-health--a Canadian perspective.

Science.gov (United States)

Alvarez, Richard C

2004-01-01

Canadians value their health care system above any other social programme. Canada's system of health care faces significant financial and population pressures, relating to cost, access, quality, accountability, and the intergration of information and communication technologies (ICTs). The health-system also faces certain unique challenges that include care delivery within a highly decentralised system of financing and accountability, and care delivery to a significant portion of the population sparsely distributed across a land mass of 10 million square kilometres, in areas of extreme climatic conditions. All of these challenges are significant catalysts in the development of technologies that aim to significantly mitigate or eliminate these selfsame challenges. The system is undergoing widespread review, nationally and within each province and territory, where the bulk of care provision is financed and managed. The challenges are being addressed by national, regional and provincial initiatives in the public, private and not-for-profit sectors. The promise of e-health lies in the manner and degree to which it can mitigate or resolve these challenges to the health system and build on advancements in ICTs supporting the development of a health infostructure. Canada is actively developing and implementing technological solutions to deliver health information and health care services across the country. These solutions, while exciting and promising, also present new challenges, particularly in regard to acceptable standards, choice of technologies, overcoming traditional jurisdictional boundaries, up-front investment, and privacy and confidentiality. Many organizations and governments are working to address these challenges. Canada Health Infoway, a not-for-profit corporation, was founded by the first ministers in 2001 to accelerate the establishment of an interoperable, pan-Canadian electronic health record. It works with partners in the federal, provincial and

SU-E-J-223: A BOLD Contrast Imaging Sequence to Evaluate Oxygenation Changes Due to Breath Holding for Breast Radiotherapy: A Pilot Study

International Nuclear Information System (INIS)

Adamson, J; Chang, Z; Cai, J; Palta, M; Horton, J; Yin, F; Blitzblau, R

2015-01-01

Purpose: To develop a robust MRI sequence to measure BOLD breath hold induced contrast in context of breast radiotherapy. Methods: Two sequences were selected from prior studies as candidates to measure BOLD contrast attributable to breath holding within the breast: (1) T2* based Gradient Echo EPI (TR/TE = 500/41ms, flip angle = 60°), and (2) T2 based Single Shot Fast Spin Echo (SSFSE) (TR/TE = 3000/60ms). We enrolled ten women post-lumpectomy for breast cancer who were undergoing treatment planning for whole breast radiotherapy. Each session utilized a 1.5T GE MRI and 4 channel breast coil with the subject immobilized prone on a custom board. For each sequence, 1–3 planes of the lumpectomy breast were imaged continuously during a background measurement (1min) and intermittent breath holds (20–40s per breath hold, 3–5 holds per sequence). BOLD contrast was quantified as correlation of changes in per-pixel intensity with the breath hold schedule convolved with a hemodynamic response function. Subtle motion was corrected using a deformable registration algorithm. Correlation with breath-holding was considered significant if p<0.001. Results: The percentage of the breast ROI with positive BOLD contrast measured by the two sequences were in agreement with a correlation coefficient of R=0.72 (p=0.02). While both sequences demonstrated areas with strong BOLD response, the response was more systematic throughout the breast for the SSFSE (T2) sequence (% breast with response in the same direction: 51.2%±0.7% for T2* vs. 68.1%±16% for T2). In addition, the T2 sequence was less prone to magnetic susceptibility artifacts, especially in presence of seroma, and provided a more robust image with little distortion or artifacts. Conclusion: A T2 SSFSE sequence shows promise for measuring BOLD contrast in the context of breast radiotherapy utilizing a breath hold technique. Further study in a larger patient cohort is warranted to better refine this novel technique

SU-E-J-223: A BOLD Contrast Imaging Sequence to Evaluate Oxygenation Changes Due to Breath Holding for Breast Radiotherapy: A Pilot Study

Energy Technology Data Exchange (ETDEWEB)

Adamson, J; Chang, Z; Cai, J; Palta, M; Horton, J; Yin, F; Blitzblau, R [Duke University Medical Center, Durham, NC (United States)

2015-06-15

Purpose: To develop a robust MRI sequence to measure BOLD breath hold induced contrast in context of breast radiotherapy. Methods: Two sequences were selected from prior studies as candidates to measure BOLD contrast attributable to breath holding within the breast: (1) T2* based Gradient Echo EPI (TR/TE = 500/41ms, flip angle = 60°), and (2) T2 based Single Shot Fast Spin Echo (SSFSE) (TR/TE = 3000/60ms). We enrolled ten women post-lumpectomy for breast cancer who were undergoing treatment planning for whole breast radiotherapy. Each session utilized a 1.5T GE MRI and 4 channel breast coil with the subject immobilized prone on a custom board. For each sequence, 1–3 planes of the lumpectomy breast were imaged continuously during a background measurement (1min) and intermittent breath holds (20–40s per breath hold, 3–5 holds per sequence). BOLD contrast was quantified as correlation of changes in per-pixel intensity with the breath hold schedule convolved with a hemodynamic response function. Subtle motion was corrected using a deformable registration algorithm. Correlation with breath-holding was considered significant if p<0.001. Results: The percentage of the breast ROI with positive BOLD contrast measured by the two sequences were in agreement with a correlation coefficient of R=0.72 (p=0.02). While both sequences demonstrated areas with strong BOLD response, the response was more systematic throughout the breast for the SSFSE (T2) sequence (% breast with response in the same direction: 51.2%±0.7% for T2* vs. 68.1%±16% for T2). In addition, the T2 sequence was less prone to magnetic susceptibility artifacts, especially in presence of seroma, and provided a more robust image with little distortion or artifacts. Conclusion: A T2 SSFSE sequence shows promise for measuring BOLD contrast in the context of breast radiotherapy utilizing a breath hold technique. Further study in a larger patient cohort is warranted to better refine this novel technique.

76 FR 54717 - Supervised Securities Holding Companies Registration

Science.gov (United States)

2011-09-02

... other financial statements submitted to the securities holding company's current consolidated supervisor... Y-9ES), The Supplement to the Consolidated Financial Statements for Bank Holding Companies (FR Y-9CS... Companies (FR Y-6), The Report of Foreign Banking Organizations (FR Y-7), The Consolidated Financial...

7 CFR 981.52 - Holding requirement and delivery.

Science.gov (United States)

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Holding requirement and delivery. 981.52 Section 981.52 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... delivery. Each handler shall, at all times, hold in his possession or under his control, in proper storage...

Elicited vs. voluntary promises

NARCIS (Netherlands)

Ismayilov, H.; Potters, Jan

2017-01-01

We set up an experiment with pre-play communication to study the impact of promise elicitation by trustors from trustees on trust and trustworthiness. When given the opportunity a majority of trustors solicits a promise from the trustee. This drives up the promise making rate by trustees to almost

The promising opportunity of dismantlement

International Nuclear Information System (INIS)

Anon.

2009-01-01

Civil engineering, mechanics and waste conditioning companies are thriving around the market of nuclear facilities dismantlement which is promised to a huge development in the coming decade. This paper presents a map of the opportunities of the dismantlement market throughout Europe (research and power reactors, fuel fabrication plants, spent fuel reprocessing plants) and a cost estimation of a given dismantling work with respect to the different steps of the work. In France a small core of about twenty companies is involved in nuclear dismantlement but the French market is also looking towards foreign specialists of this activity. The British market is also targeted by the French companies but for all the actors the technological or commercial advance gained today will be determining for the future markets. (J.S.)

A Numerical Method to Generate Reference Trajectories for Optimization Methods to Support Low-Thrust Mission Design

Data.gov (United States)

National Aeronautics and Space Administration — The recent success of missions employing low thrust propulsion systems has demonstrated the promise this technology holds for a wide array of future applications,...

PBL og de sammensatte hold på kandidatuddannelser

DEFF Research Database (Denmark)

Engen, Mie; Fallov, Mia Arp; Jensen, Rune Hagel Skaarup

Denne rapport omhandler pædagogiske udfordringer og muligheder i Aalborgs Problembaserede Læringstilgang (PBL), når den omsættes til pædagogisk og didaktisk handling på kandidatuddannelser med sammensatte hold. Sammensatte hold betyder i denne sammenhæng kandidatuddannelser, hvor de optagne stude...

34 CFR 200.73 - Applicable hold-harmless provisions.

Science.gov (United States)

2010-07-01

... meet the eligibility requirements for a basic grant, targeted grant, or education finance incentive... Improving Basic Programs Operated by Local Educational Agencies Allocations to Leas § 200.73 Applicable hold... provided in § 200.100(d), an SEA must apply the hold-harmless requirement separately for basic grants...

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Science.gov (United States)

Bartlett, Frederick R.; Colgan, Ruth M.; Donovan, Ellen M.; Carr, Karen; Landeg, Steven; Clements, Nicola; McNair, Helen A.; Locke, Imogen; Evans, Philip M.; Haviland, Joanne S.; Yarnold, John R.; Kirby, Anna M.

2014-01-01

Breath-holding techniques reduce the amount of radiation received by cardiac structures during tangential-field left breast radiotherapy. With these techniques, patients hold their breath while radiotherapy is delivered, pushing the heart down and away from the radiotherapy field. Despite clear dosimetric benefits, these techniques are not yet in widespread use. One reason for this is that commercially available solutions require specialist equipment, necessitating not only significant capital investment, but often also incurring ongoing costs such as a need for daily disposable mouthpieces. The voluntary breath-hold technique described here does not require any additional specialist equipment. All breath-holding techniques require a surrogate to monitor breath-hold consistency and whether breath-hold is maintained. Voluntary breath-hold uses the distance moved by the anterior and lateral reference marks (tattoos) away from the treatment room lasers in breath-hold to monitor consistency at CT-planning and treatment setup. Light fields are then used to monitor breath-hold consistency prior to and during radiotherapy delivery. PMID:25046661

Effect of holding office on the behavior of politicians.

Science.gov (United States)

Enemark, Daniel; Gibson, Clark C; McCubbins, Mathew D; Seim, Brigitte

2016-11-29

Reciprocity is central to our understanding of politics. Most political exchanges-whether they involve legislative vote trading, interbranch bargaining, constituent service, or even the corrupt exchange of public resources for private wealth-require reciprocity. But how does reciprocity arise? Do government officials learn reciprocity while holding office, or do recruitment and selection practices favor those who already adhere to a norm of reciprocity? We recruit Zambian politicians who narrowly won or lost a previous election to play behavioral games that provide a measure of reciprocity. This combination of regression discontinuity and experimental designs allows us to estimate the effect of holding office on behavior. We find that holding office increases adherence to the norm of reciprocity. This study identifies causal effects of holding office on politicians' behavior.

Ecoinformatics (Big Data) for Agricultural Entomology: Pitfalls, Progress, and Promise.

Science.gov (United States)

Rosenheim, Jay A; Gratton, Claudio

2017-01-31

Ecoinformatics, as defined in this review, is the use of preexisting data sets to address questions in ecology. We provide the first review of ecoinformatics methods in agricultural entomology. Ecoinformatics methods have been used to address the full range of questions studied by agricultural entomologists, enabled by the special opportunities associated with data sets, nearly all of which have been observational, that are larger and more diverse and that embrace larger spatial and temporal scales than most experimental studies do. We argue that ecoinformatics research methods and traditional, experimental research methods have strengths and weaknesses that are largely complementary. We address the important interpretational challenges associated with observational data sets, highlight common pitfalls, and propose some best practices for researchers using these methods. Ecoinformatics methods hold great promise as a vehicle for capitalizing on the explosion of data emanating from farmers, researchers, and the public, as novel sampling and sensing techniques are developed and digital data sharing becomes more widespread.

Realizing the promise of social psychology in improving public health.

Science.gov (United States)

Klein, William M P; Shepperd, James A; Suls, Jerry; Rothman, Alexander J; Croyle, Robert T

2015-02-01

The theories, phenomena, empirical findings, and methodological approaches that characterize contemporary social psychology hold much promise for addressing enduring problems in public health. Indeed, social psychologists played a major role in the development of the discipline of health psychology during the 1970s and 1980s. The health domain allows for the testing, refinement, and application of many interesting and important research questions in social psychology, and offers the discipline a chance to enhance its reach and visibility. Nevertheless, in a review of recent articles in two major social-psychological journals (Personality and Social Psychology Bulletin and Journal of Personality and Social Psychology), we found that only 3.2% of 467 studies explored health-related topics. In this article, we identify opportunities for research at the interface of social psychology and health, delineate barriers, and offer strategies that can address these barriers as the discipline continues to evolve. © 2014 by the Society for Personality and Social Psychology, Inc.

Technological Advances in the Treatment of Trauma: A Review of Promising Practices

Science.gov (United States)

Paul, Lisa A.; Hassija, Christina M.; Clapp, Joshua D.

2012-01-01

Given the availability of empirically supported practices for addressing posttraumatic stress disorder and other forms of trauma-related distress, the development and implementation of new technology to deliver these treatments is exciting. Technological innovations in this literature aim to expand availability of empirically based intervention,…

Nonviral Technologies for Gene Therapy in Cardiovascular Research

Directory of Open Access Journals (Sweden)

Cheng-Huang Su

2008-06-01

Full Text Available Gene therapy, which is still at an experimental stage, is a technique that attempts to correct or prevent a disease by delivering genes into an individual's cells and tissues. In gene delivery, a vector is a vehicle for transferring genetic material into cells and tissues. Synthetic vectors are considered to be prerequisites for gene delivery, because viral vectors have fundamental problems in relation to safety issues as well as large-scale production. Among the physical approaches, ultrasound with its associated bioeffects such as acoustic cavitation, especially inertial cavitation, can increase the permeability of cell membranes to macromolecules such as plasmid DNA. Microbubbles or ultrasound contrast agents lower the threshold for cavitation by ultrasound energy. Furthermore, ultrasound-enhanced gene delivery using polymers or other nonviral vectors may hold much promise for the future but is currently at the preclinical stage. We all know aging is cruel and inevitable. Currently, among the promising areas for gene therapy in acquired diseases, the incidences of cancer and ischemic cardiovascular diseases are strongly correlated with the aging process. As a result, gene therapy technology may play important roles in these diseases in the future. This brief review focuses on understanding the barriers to gene transfer as well as describing the useful nonviral vectors or tools that are applied to gene delivery and introducing feasible models in terms of ultrasound-based gene delivery.

Genetic manipulations in aquaculture: a review of stock improvement by classical and modern technologies.

Science.gov (United States)

Hulata, G

2001-01-01

The aim of this review was to highlight the extent to which the genetic technologies are implemented by the aquaculture industry. The review shows that some of the modern genetic technologies are already extensively applied by the diverse aquaculture industries, though not to the same extent for all important aquacultured species (according to FAO 1998 figures). Some species (common carp, Atlantic salmon, rainbow trout, channel catfish, Nile tilapia, and the Pacific oyster) received concentrated breeding efforts, while other major cultured species (Chinese and Indian carps and the giant tiger shrimp) received, so far, relatively limited attention, and a few species (Yesso scallop, blue mussel, white Amur bream, and milkfish) have, apparently, not been genetically improved at all. Most of the genetically improved strains reaching the aquaculture industry were developed through traditional selective breeding (selection, crossbreeding, and hybridization). Emerging, more modern technologies for genetic manipulation seem to take 10-20 years from being established experimentally until applications affect the industry. Thus, chromosome-set and sex manipulations started to affect the industry during the 1980's and 1990's. DNA marker technology and gene manipulations have yet hardly affected the industry. The former have not matured yet, but hold much promise. The latter could have affected the industry already had it not been restricted by public concern.

Antigen Loss Variants: Catching Hold of Escaping Foes.

Science.gov (United States)

Vyas, Maulik; Müller, Rolf; Pogge von Strandmann, Elke

2017-01-01

Since mid-1990s, the field of cancer immunotherapy has seen steady growth and selected immunotherapies are now a routine and preferred therapeutic option of certain malignancies. Both active and passive cancer immunotherapies exploit the fact that tumor cells express specific antigens on the cell surface, thereby mounting an immune response specifically against malignant cells. It is well established that cancer cells typically lose surface antigens following natural or therapy-induced selective pressure and these antigen-loss variants are often the population that causes therapy-resistant relapse. CD19 and CD20 antigen loss in acute lymphocytic leukemia and chronic lymphocytic leukemia, respectively, and lineage switching in leukemia associated with mixed lineage leukemia (MLL) gene rearrangements are well-documented evidences in this regard. Although increasing number of novel immunotherapies are being developed, majority of these do not address the control of antigen loss variants. Here, we review the occurrence of antigen loss variants in leukemia and discuss the therapeutic strategies to tackle the same. We also present an approach of dual-targeting immunoligand effectively retargeting NK cells against antigen loss variants in MLL-associated leukemia. Novel immunotherapies simultaneously targeting more than one tumor antigen certainly hold promise to completely eradicate tumor and prevent therapy-resistant relapses.

Development of hold down plate of INGLE fuel assembly

International Nuclear Information System (INIS)

Kim, Hyeong Koo; Kim, Kyu Tae

1996-07-01

Hold down plate for the INGLE fuel which has been designed for high performance in the standpoints of thermal margin and structural integrity compared to current fuel for YGN 3/4 and UCN 3/4 has been developed and its structural integrity has been verified based on the eh stress analysis. The design feature of the developed hold down plate has not only perfect compatibility with the reactor internals of Korea standard reactor, but also brand-new locking mechanism between upper tie plate and guide tubes. This locking mechanism introduced to the INGLE fuel provides very simple and reliable reconstitutability. In this report, finite element stress analysis with the aid of the ANSYS code as a solver and the MSC/PATRAN code as a pre and post processor were performed to verify structural integrity of the hold down plate considering various load cases which seem to be applied to the hold down plate during its lifetime. Based on the analysis results, the developed hold down plate for INGLE fuel sustains structural integrity under considered load conditions. 3 tabs., 16 figs., 9 refs. (Author)

Augmented Reality Based Doppler Lidar Data Visualization: Promises and Challenges

Science.gov (United States)

Cherukuru, N. W.; Calhoun, R.

2016-06-01

Augmented reality (AR) is a technology in which the enables the user to view virtual content as if it existed in real world. We are exploring the possibility of using this technology to view radial velocities or processed wind vectors from a Doppler wind lidar, thus giving the user an ability to see the wind in a literal sense. This approach could find possible applications in aviation safety, atmospheric data visualization as well as in weather education and public outreach. As a proof of concept, we used the lidar data from a recent field campaign and developed a smartphone application to view the lidar scan in augmented reality. In this paper, we give a brief methodology of this feasibility study, present the challenges and promises of using AR technology in conjunction with Doppler wind lidars.

A New Rootedness? Education in the Technological Age

Science.gov (United States)

Glendinning, Simon

2018-01-01

This paper explores the challenges facing educators in a time when modern technology, and especially modern social technology, has an increasingly powerful hold on our lives. The educational challenge does not primarily concern questions concerning the use of technology in the classroom, or as part of the learning environment, but a changeover in…

Partnering Events | NCI Technology Transfer Center | TTC

Science.gov (United States)

Our team of technology transfer specialists has specialized training in invention reporting, patenting, patent strategy, executing technology transfer agreements and marketing. TTC is comprised of professionals with diverse legal, scientific, and business/marketing expertise. Most of our staff hold doctorate-level technical and/or legal training.

A Physiologically Informed Virtual Reality Based Social Communication System for Individuals with Autism

Science.gov (United States)

Lahiri, Uttama; Bekele, Esubalew; Dohrmann, Elizabeth; Warren, Zachary; Sarkar, Nilanjan

2015-01-01

Clinical applications of advanced technology may hold promise for addressing impairments associated with autism spectrum disorders (ASD). This project evaluated the application of a novel physiologically responsive virtual reality based technological system for conversation skills in a group of adolescents with ASD. The system altered components…

Land holds promise of peace in Colombia | IDRC - International ...

International Development Research Centre (IDRC) Digital Library (Canada)

2011-11-08

Nov 8, 2011 ... Land Seizures in Northern Colombia and their Effect on the Peasant Movement ... demand attention and a meaningful response from the society around them. ... With funding from IDRC, the Historical Memory Group's work on ...

EFFECT OF SHADOWING AND MULTIPATH FADING ON THE ...

African Journals Online (AJOL)

Nigerian Journal of Technology ... The traditional macro-only network have been proved ineffective when ... This holds a great promise for adaptive space-based wireless sensor networks, formation-flying satellites and constellations.

Autonomous Alignment Advancements for Eye-safe Coherent Lidar, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — Eye-safe coherent lidar technology holds increasing promise of meeting NASA's demanding remote 3D space winds goal near term. Highly autonomous, long-range coherent...

Stabilized helical peptides: overview of the technologies and its impact on drug discovery.

Science.gov (United States)

Klein, Mark

2017-11-01

Protein-protein interactions are predominant in the workings of all cells. Until now, there have been a few successes in targeting protein-protein interactions with small molecules. Peptides may overcome some of the challenges of small molecules in disrupting protein-protein interactions. However, peptides present a new set of challenges in drug discovery. Thus, the study of the stabilization of helical peptides has been extensive. Areas covered: Several technological approaches to helical peptide stabilization have been studied. In this review, stapled peptides, foldamers, and hydrogen bond surrogates are discussed. Issues regarding design principles are also discussed. Furthermore, this review introduces select computational techniques used to aid peptide design and discusses clinical trials of peptides in a more advanced stage of development. Expert opinion: Stabilized helical peptides hold great promise in a wide array of diseases. However, the field is still relatively new and new design principles are emerging. The possibilities of peptide modification are quite extensive and expanding, so the design of stabilized peptides requires great attention to detail in order to avoid a large number of failed lead peptides. The start of clinical trials with stapled peptides is a promising sign for the future.

Intangible Capital and Corporate Cash Holdings: Theory and Evidence

OpenAIRE

Dalida Kadyrzhanova; Antonio Falato; Jae Sim

2012-01-01

The rise in intangible capital is a fundamental driver of the secular trend in US corporate cash holdings over the last decades. We construct a new measure of intangible capital and show that intangible capital is the most important firm-level determinant of corporate cash holdings. Our measure accounts for almost as much of the secular increase in cash since the 1980s as all other standard determinants together. We then develop a new model of corporate cash holdings that introduces intangibl...

26 CFR 301.6501(f)-1 - Personal holding company tax.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 18 2010-04-01 2010-04-01 false Personal holding company tax. 301.6501(f)-1... Collection § 301.6501(f)-1 Personal holding company tax. If a corporation which is a personal holding company... time during the last half of such taxable year, more than 50 percent in value of the outstanding...

Effect of holding office on the behavior of politicians

Science.gov (United States)

Enemark, Daniel; Gibson, Clark C.; McCubbins, Mathew D.; Seim, Brigitte

2016-01-01

Reciprocity is central to our understanding of politics. Most political exchanges—whether they involve legislative vote trading, interbranch bargaining, constituent service, or even the corrupt exchange of public resources for private wealth—require reciprocity. But how does reciprocity arise? Do government officials learn reciprocity while holding office, or do recruitment and selection practices favor those who already adhere to a norm of reciprocity? We recruit Zambian politicians who narrowly won or lost a previous election to play behavioral games that provide a measure of reciprocity. This combination of regression discontinuity and experimental designs allows us to estimate the effect of holding office on behavior. We find that holding office increases adherence to the norm of reciprocity. This study identifies causal effects of holding office on politicians’ behavior. PMID:27856736

Neuroimaging in psychiatric pharmacogenetics research: the promise and pitfalls.

Science.gov (United States)

Falcone, Mary; Smith, Ryan M; Chenoweth, Meghan J; Bhattacharjee, Abesh Kumar; Kelsoe, John R; Tyndale, Rachel F; Lerman, Caryn

2013-11-01

The integration of research on neuroimaging and pharmacogenetics holds promise for improving treatment for neuropsychiatric conditions. Neuroimaging may provide a more sensitive early measure of treatment response in genetically defined patient groups, and could facilitate development of novel therapies based on an improved understanding of pathogenic mechanisms underlying pharmacogenetic associations. This review summarizes progress in efforts to incorporate neuroimaging into genetics and treatment research on major psychiatric disorders, such as schizophrenia, major depressive disorder, bipolar disorder, attention-deficit/hyperactivity disorder, and addiction. Methodological challenges include: performing genetic analyses in small study populations used in imaging studies; inclusion of patients with psychiatric comorbidities; and the extensive variability across studies in neuroimaging protocols, neurobehavioral task probes, and analytic strategies. Moreover, few studies use pharmacogenetic designs that permit testing of genotype × drug effects. As a result of these limitations, few findings have been fully replicated. Future studies that pre-screen participants for genetic variants selected a priori based on drug metabolism and targets have the greatest potential to advance the science and practice of psychiatric treatment.

Technology Roadmaps: Concentrating Solar Power

Energy Technology Data Exchange (ETDEWEB)

NONE

2010-07-01

The emerging technology known as concentrating solar power, or CSP, holds much promise for countries with plenty of sunshine and clear skies. Its electrical output matches well the shifting daily demand for electricity in places where airconditioning systems are spreading. When backed up by thermal storage facilities and combustible fuel, it offers utilities electricity that can be dispatched when required, enabling it to be used for base, shoulder and peak loads. Within about one to two decades, it will be able to compete with coal plants that emit high levels of CO2. The sunniest regions, such as North Africa, may be able to export surplus solar electricity to neighbouring regions, such as Europe, where demand for electricity from renewable sources is strong. In the medium-to-longer term, concentrating solar facilities can also produce hydrogen, which can be blended with natural gas, and provide low-carbon liquid fuels for transport and other end-use sectors. For CSP to claim its share of the coming energy revolution, concerted action is required over the next ten years by scientists, industry, governments, financing institutions and the public. This roadmap is intended to help drive these indispensable developments.

Chelation technology: a promising green approach for resource management and waste minimization.

Science.gov (United States)

Chauhan, Garima; Pant, K K; Nigam, K D P

2015-01-01

Green chemical engineering recognises the concept of developing innovative environmentally benign technologies to protect human health and ecosystems. In order to explore this concept for minimizing industrial waste and for reducing the environmental impact of hazardous chemicals, new greener approaches need to be adopted for the extraction of heavy metals from industrial waste. In this review, a range of conventional processes and new green approaches employed for metal extraction are discussed in brief. Chelation technology, a modern research trend, has shown its potential to develop sustainable technology for metal extraction from various metal-contaminated sites. However, the interaction mechanism of ligands with metals and the ecotoxicological risk associated with the increased bioavailability of heavy metals due to the formation of metal-chelant complexes is still not sufficiently explicated in the literature. Therefore, a need was felt to provide a comprehensive state-of-the-art review of all aspects associated with chelation technology to promote this process as a green chemical engineering approach. This article elucidates the mechanism and thermodynamics associated with metal-ligand complexation in order to have a better understanding of the metal extraction process. The effects of various process parameters on the formation and stability of complexes have been elaborately discussed with respect to optimizing the chelation efficiency. The non-biodegradable attribute of ligands is another important aspect which is currently of concern. Therefore, biotechnological approaches and computational tools have been assessed in this review to illustrate the possibility of ligand degradation, which will help the readers to look for new environmentally safe mobilizing agents. In addition, emerging trends and opportunities in the field of chelation technology have been summarized and the diverse applicability of chelation technology in metal extraction from

The Holding Company as an Instrument of Companies’ Tax-Financial Policy Formation

Directory of Open Access Journals (Sweden)

Dominik Gajewski

2013-03-01

Full Text Available The aim of this article is to present the holding institution as an economic and taxation solution. This article describes the holding company, indicates its advantages and disadvantages, and compares it to similar solutions. The main goal of holding companies is to change tax policies. As a result of these institutions, companies can change their tax status and economic situation. The holding institution influences the economic development of its constituent companies. The functioning of a holding company also has great importance for economic development. Establishing holdings is a worldwide trend that may be realised through various models.

Specifics of financial management of holdings when managing cash-flow

Directory of Open Access Journals (Sweden)

David Ficbauer

2010-01-01

Full Text Available Concentration and cooperation belong to the main attributes of the modern business life. Business competition makes the start of a new business more difficult. Just the moment of concentration and cooperation can make the break to the new business easier. This can be achieved by including new businesses into holding companies. Basically there are two ways how to do a business. These depend on whether company carries out many lines of business or on the amount of asset. The first way is to cover everything with one enterprise and thus to create one accounting unit. The second way is based on a foundation of a holding structure with subsidiaries and the holder on the top. In fact holding is a specific way how to cover business by many subsidiaries.The goal of this article is to describe specifics of a financial management of holdings when managing cash-flow. The focus is on reasons of holding structure and usage of both theoretical and other models of managing cash such as Baumol model, Miller-Orr model and Beránek model. As transfers within the holding organization belong to the main advantageous of holding, the way how to transfer finance from one subsidiary to other or from subsidiary to holder or reversely is handled here.

Small forest holdings could be combined for hunting leases

Science.gov (United States)

John J. Stransky; Lowell K. Halls

1969-01-01

Most forest land acreage in the South is in small holdings. Much-needed hunting land, and income for rural landowners, could be provided by combining small forest holdings into large units and teasing the hunting rights.

Why do firms hold so much cash? A tax-based explanation

OpenAIRE

C. Fritz Foley; Jay C. Hartzell; Sheridan Titman; Garry Twite

2006-01-01

U.S. corporations hold significant amounts of cash on their balance sheets, and these cash holdings have been justified in the existing empirical literature by transaction costs and precautionary motives. An additional explanation, considered in this study, is that U.S. multinational firms hold cash in their foreign subsidiaries because of the tax costs associated with repatriating foreign income. Consistent with this hypothesis, firms that face higher repatriation tax burdens hold higher lev...

Keeping the Promise

Science.gov (United States)

Whissemore, Tabitha

2016-01-01

Since its launch in September 2015, Heads Up America has collected information on nearly 125 promise programs across the country, many of which were instituted long before President Barack Obama announced the America's College Promise (ACP) plan in 2015. At least 27 new free community college programs have launched in states, communities, and at…

Extending emotion and decision-making beyond the laboratory: The promise of palliative care contexts.

Science.gov (United States)

Ferrer, Rebecca A; Padgett, Lynne; Ellis, Erin M

2016-08-01

Although laboratory-based research on emotion and decision-making holds the distinct advantage of rigorous experimental control conditions that allow causal inferences, the question of how findings in a laboratory generalize to real-world settings remains. Identifying ecologically valid, real-world opportunities to extend laboratory findings is a valuable means of advancing this field. Palliative care-or care intended to provide relief from serious illness and aging-related complications during treatment or at the end of life-provides a particularly rich opportunity for such work. Here, we present an overview of palliative care, summarize existing research on emotion and palliative care decision-making, highlight challenges associated with conducting such research, outline examples of collaborative projects leveraging palliative care as a context for generating fundamental knowledge about emotion and decision-making, and describe the resources and collaborations necessary to conduct this type of research. In sum, palliative care holds unique promise as an emotionally laden context in which to answer fundamental questions about emotion and decision-making that extends our theoretical understanding of the role of emotion in high-stakes decision-making while simultaneously generating knowledge that can improve palliative care implementation. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Impact of breath holding on cardiovascular respiratory and cerebrovascular health.

Science.gov (United States)

Dujic, Zeljko; Breskovic, Toni

2012-06-01

Human underwater breath-hold diving is a fascinating example of applied environmental physiology. In combination with swimming, it is one of the most popular forms of summer outdoor physical activities. It is performed by a variety of individuals ranging from elite breath-hold divers, underwater hockey and rugby players, synchronized and sprint swimmers, spear fishermen, sponge harvesters and up to recreational swimmers. Very few data currently exist concerning the influence of regular breath holding on possible health risks such as cerebrovascular, cardiovascular and respiratory diseases. A literature search of the PubMed electronic search engine using keywords 'breath-hold diving' and 'apnoea diving' was performed. This review focuses on recent advances in knowledge regarding possibly harmful physiological changes and/or potential health risks associated with breath-hold diving. Available evidence indicates that deep breath-hold dives can be very dangerous and can cause serious acute health problems such a collapse of the lungs, barotrauma at descent and ascent, pulmonary oedema and alveolar haemorrhage, cardiac arrest, blackouts, nitrogen narcosis, decompression sickness and death. Moreover, even shallow apnoea dives, which are far more frequent, can present a significant health risk. The state of affairs is disturbing as athletes, as well as recreational individuals, practice voluntary apnoea on a regular basis. Long-term health risks of frequent maximal breath holds are at present unknown, but should be addressed in future research. Clearly, further studies are needed to better understand the mechanisms related to the possible development or worsening of different clinical disorders in recreational or competitive breath holding and to determine the potential changes in training/competition regimens in order to prevent these adverse events.

Leverage, Asymmetric Information, Firm Value, and Cash Holdings in Indonesia

Directory of Open Access Journals (Sweden)

Aldea Mita Cheryta

2018-02-01

Full Text Available This research aimed to analyze the effect of leverage and asymmetry information on the firm value through cash holding as mediation variable. The populations of this research were all the firms which listed on the Indonesia Stock Exchange since 2012 – 2015. A sample of this research was saturated sample and census, consisted 56 firms related the population criteria.  This research used secondary data from the firm financial report through path analysis method. This research showed that leverage had a negative effect on the cash holdings, asymmetry information had a negative effect on the firm value through cash holding, and cash holding had a negative effect on the firm value.  With leverage and effect on cash, holding cannot affect the firm value, due to investor risk-averse, investor risk seeker, and neutral investor has their own point of view in assessing the company. Cash holdings can lead to asymmetric information that can lead to agency conflict that can affect a company's performance, so that indirectly, with the existence of asymmetry information had an effect on the declining the firm value. 

WorldWide Telescope and Google Sky: New Technologies to Engage Students and the Public

Science.gov (United States)

Landsberg, R. H.; Subbarao, M. U.; Dettloff, L.

2010-08-01

New, visually rich, astronomical software environments coupled with large web-accessible data sets hold the promise of new and exciting ways to teach, collaborate, and explore the universe. These freeware tools provide contextual views of astronomical objects, real time access to multi-wavelength sky surveys, and, most importantly, the ability to incorporate new data and to produce user created content. This interactive panel examined the capabilities of Google Sky and WorldWide Telescope, and explored case studies of how these tools have been used to create compelling and participatory educational experiences in both formal (i.e., K-12 and undergraduate non-science majors classrooms), and informal (e.g., museum) settings. The overall goal of this session was to stimulate a discussion about future uses of these technologies. Substantial time was allotted for participants to create conceptual designs of learning experiences for use at their home institutions, with feedback provided by the panel members. Activities included technical discussions (e.g., mechanisms for incorporating new data and dissemination tools), exercises in narrative preparation, and a brainstorming session to identify potential future uses of these technologies.

A Hold-down Margin Assessment using Statistical Method for the PWR Fuel Assembly

International Nuclear Information System (INIS)

Jeon, S. Y.; Park, N. K.; Lee, K. S.; Kim, H. K.

2007-01-01

The hold-down springs provide an acceptable hold down force against hydraulic uplift force absorbing the length change of the fuel assembly relative to the space between the upper and lower core plates in PWR. These length changes are mainly due to the thermal expansion, irradiation growth and creep down of the fuel assemblies. There are two kinds of hold-down springs depending on the different design concept of the reactor internals of the PWR in Korea, one is a leaf-type hold down spring for Westinghouse type plants and the other is a coil-type hold-down spring for OPR1000 (Optimized Power Reactor 1000). There are four sets of hold-down springs in each fuel assembly for leaf type hold-down spring and each set of the hold-down springs consists of multiple tapered leaves to form a cantilever leaf spring set. The length, width and thickness of the spring leaves are selected to provide the desired spring constant, deflection range, and hold down force. There are four coil springs in each fuel assembly for coil-type hold-down spring. In this study, the hold-down forces and margins were calculated for the leaf-type and coil-type hold-down springs considering geometrical data of the fuel assembly and its components, length changes of the fuel assembly due to thermal expansion, irradiation growth, creep, and irradiation relaxation. The hold-down spring forces were calculated deterministically and statistically to investigate the benefit of the statistical calculation method in view of hold-down margin. The Monte-Carlo simulation method was used for the statistical hold down force calculation

Using Rapid Improvement Events for Disaster After-Action Reviews: Experience in a Hospital Information Technology Outage and Response.

Science.gov (United States)

Little, Charles M; McStay, Christopher; Oeth, Justin; Koehler, April; Bookman, Kelly

2018-02-01

The use of after-action reviews (AARs) following major emergency events, such as a disaster, is common and mandated for hospitals and similar organizations. There is a recurrent challenge of identified problems not being resolved and repeated in subsequent events. A process improvement technique called a rapid improvement event (RIE) was used to conduct an AAR following a complete information technology (IT) outage at a large urban hospital. Using RIE methodology to conduct the AAR allowed for the rapid development and implementation of major process improvements to prepare for future IT downtime events. Thus, process improvement methodology, particularly the RIE, is suited for conducting AARs following disasters and holds promise for improving outcomes in emergency management. Little CM , McStay C , Oeth J , Koehler A , Bookman K . Using rapid improvement events for disaster after-action reviews: experience in a hospital information technology outage and response. Prehosp Disaster Med. 2018;33(1):98-100.

Liquid holding recovery and photoreactivation of the ultraviolet-inactivated vibrios

International Nuclear Information System (INIS)

Banerjee, S.K.; Chatterjee, S.N.

1981-01-01

The kinetics of liquid holding recovery and photoreactivation of the ultra-violet-inactivated vibrios have been investigated. Photoreactivation was highest (about 80%) for Vibrio cholerae (classical) strains but the liquid holding recovery was highest (about 29%) for Vibrio parahemolyticus ones. Significance of the differences between any two of the four vibrio biotypes in respect of their liquid holding recovery and also photoreactivation was analysed statistically. (auth.)

The Future of Learning Technology: Some Tentative Predictions

Science.gov (United States)

Rushby, Nick

2013-01-01

This paper is a snapshot of an evolving vision of what the future may hold for learning technology. It offers three personal visions of the future and raises many questions that need to be explored if learning technology is to realise its full potential.

Breath-hold gadolinium-enhanced MRA : clinical application

International Nuclear Information System (INIS)

Kang, Sung Gwon; Kang, Ji Hee; Kim, Won Hong; Lim, Myung Kwan; Cho, Young Kook; Cho, Soon Gu; Suh, Chang Hae

1998-01-01

The purpose of this study is to compare breath-hold gadolinium enhanced MR angiography (MRA) with digital subtraction angiography. Ten patients underwent angiography and breath-hold gadolinium enhanced MRA; the latter performed at 1.5T with 3D FSPGR after a bolus injection of gadopentetate dimeglumine (0.4m mol/kg). Seven of ten pathologic conditions (70%) evaluated by both techniques had a similar appearance. The conditions examined were as follows: the artery feeding renal cell carcinoma(n=2); renal artery stenosis (n=2); pulmonary AVM(n=2); abdominal aortic aneurysm (n=1); atheromatous plaque in the lower abdominal aorta (n=1); an enlarged bronchial artery (n=1); and an aberrant renal artery (n=1). For evaluating an anatomic relationship, a reconstructed 3D image obtained by MRA is more advantageous. Breath hold contrast enhanced MRA is a potentially useful noninvasive screening method for detecting vascular abnormality of the aorta and its branches. (author). 13 refs., 1 tab., 4 figs

Breath-hold gadolinium-enhanced MRA : clinical application

Energy Technology Data Exchange (ETDEWEB)

Kang, Sung Gwon; Kang, Ji Hee; Kim, Won Hong; Lim, Myung Kwan; Cho, Young Kook; Cho, Soon Gu; Suh, Chang Hae [Inha University Hospital, Inchon (Korea, Republic of)

1998-05-01

The purpose of this study is to compare breath-hold gadolinium enhanced MR angiography (MRA) with digital subtraction angiography. Ten patients underwent angiography and breath-hold gadolinium enhanced MRA; the latter performed at 1.5T with 3D FSPGR after a bolus injection of gadopentetate dimeglumine (0.4m mol/kg). Seven of ten pathologic conditions (70%) evaluated by both techniques had a similar appearance. The conditions examined were as follows: the artery feeding renal cell carcinoma(n=2); renal artery stenosis (n=2); pulmonary AVM(n=2); abdominal aortic aneurysm (n=1); atheromatous plaque in the lower abdominal aorta (n=1); an enlarged bronchial artery (n=1); and an aberrant renal artery (n=1). For evaluating an anatomic relationship, a reconstructed 3D image obtained by MRA is more advantageous. Breath hold contrast enhanced MRA is a potentially useful noninvasive screening method for detecting vascular abnormality of the aorta and its branches. (author). 13 refs., 1 tab., 4 figs.

Corporate Cash Holdings and Shareholder Risk : Investigating the relationship between corporate cash holdings and the risk of stocks listed on the Stockholm Stock Exchange

OpenAIRE

Olausson, Jonas; Löfgren, Christoffer

2013-01-01

Corporate cash holdings is a topic constantly under review, companies hoarding cash are criticized by shareholders who rather have companies using their cash for new investments or dividend payouts. Recent academic research has discovered that levels of cash holding are high in times when risk is deemed to be high and found that levels of corporate cash holdings are substantially higher than they used to, making more coverage and a better understanding of the phenomenon crucial. This thesis i...

Review of early assessment models of innovative medical technologies.

Science.gov (United States)

Fasterholdt, Iben; Krahn, Murray; Kidholm, Kristian; Yderstræde, Knud Bonnet; Pedersen, Kjeld Møller

2017-08-01

Hospitals increasingly make decisions regarding the early development of and investment in technologies, but a formal evaluation model for assisting hospitals early on in assessing the potential of innovative medical technologies is lacking. This article provides an overview of models for early assessment in different health organisations and discusses which models hold most promise for hospital decision makers. A scoping review of published studies between 1996 and 2015 was performed using nine databases. The following information was collected: decision context, decision problem, and a description of the early assessment model. 2362 articles were identified and 12 studies fulfilled the inclusion criteria. An additional 12 studies were identified and included in the review by searching reference lists. The majority of the 24 early assessment studies were variants of traditional cost-effectiveness analysis. Around one fourth of the studies presented an evaluation model with a broader focus than cost-effectiveness. Uncertainty was mostly handled by simple sensitivity or scenario analysis. This review shows that evaluation models using known methods assessing cost-effectiveness are most prevalent in early assessment, but seems ill-suited for early assessment in hospitals. Four models provided some usable elements for the development of a hospital-based model. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.

The Holding Power of Anchors

Indian Academy of Sciences (India)

The efficiency of an anchor may be expressed as the ratio (holding force + weight of anchor). In dry sand .... the market at the beginning of the coming season in three sizes, namely 20, 35 and. 60 lb. These are ... Taylor frozen-flow hypothesis.

75 FR 21050 - V-GPO, Inc., Valesc Holdings, Inc., Venture Stores, Inc., Vertigo Theme Parks, Inc. (f/k/a Snap2...

Science.gov (United States)

2010-04-22

... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] V-GPO, Inc., Valesc Holdings, Inc., Venture Stores, Inc., Vertigo Theme Parks, Inc. (f/k/a Snap2 Corp.), Videolan Technologies, Inc., VisionGateway... Commission that there is a lack of current and accurate information concerning the securities of Vertigo...

The role of short rotation coppice technology in fuelwood supply in Rungwe district, Tanzania

Directory of Open Access Journals (Sweden)

G.M. Karwani

2016-06-01

Full Text Available The roles of Short Rotation Coppice (SRC Technology in fuelwood supply and offsetting CO2 emissions in the Tanzania and most African countries remain poorly understood. This study was carried in Rungwe District, Mbeya region in Tanzania, to determine trends, extent and drivers of adoption of SRC; identify various sources of household energy and assess the contribution of SRC to the total household fuelwood needs, and trees and shrub species used as sources of fuelwood. Data were collected using reconnaissance, field and social surveys and was analyzed using the Statistical Package for Social Sciences (SPSS. Results revealed that, 97.5% of local community adopted the SRC technology since 1960s. Eucalyptus spp. are mostly planted in woodlots and field boundaries while Persea americana and Leucaena leucocephala are intercropped in farmlands. The survey indicated that out of 176 tons of fuelwood used annually, 73% comes from SRC technology, 25% from non-SRC technology, and only 2% is purchased to supplement household fuelwood shortage. Local communities depend heavily on biomass energy from woodlots and farmlands where tree species like Eucalyptus spp. plays a key role in meeting the energy demand. This study demonstrates that SRC technologies like woodlots, boundary planting, and intercropping in farmland hold high promise to meet the household energy demand. If promoted and backed with strong policies and supportive land tenure, these technologies may reduce the harvesting pressure on native forests for energy demand and contribute to climate change mitigation and adaptation.

DESIGN OF INFORMATION MANAGEMENT SYSTEM OF VERTICALLY INTEGRATED AGRICULTURAL HOLDINGS

Directory of Open Access Journals (Sweden)

Александр Витальевич ШМАТКО

2015-05-01

Full Text Available The paper deals with an approach to the design and development of information systems for the management and optimization of the organizational structure of vertically integrated agricultural holdings. A review of the problems of building and improving the organizational structure of vertically integrated agricultural holding is made. A method of constructing a discrete model management structure agricultural holding, which minimizes the costs associated with attracting applicants to work, is proposed.

A review of treatment technologies for MTBE

International Nuclear Information System (INIS)

Bass, D.

1995-01-01

Available treatment technologies for methyl tertiary butyl ether (MTBE) contamination in soil, groundwater, and recovered groundwater are reviewed and assessed. MTBE contamination is becoming an important issue due to the increasing prevalence and regulation of this gasoline additive. In addition, MTBE is more soluble and more mobile in groundwater than most hydrocarbons, so it is usually the first gasoline constituent to reach sensitive receptors. Treatment of MTBE is complicated by its Henry's constant, which is lower than most other gasoline constituents. Furthermore, evidence of biodegradability of MTBE is mixed, and MTBE does not degrade rapidly abiotically. Groundwater pumping is usually employed to contain and collect MTBE-contaminated groundwater, often successfully because of its high aqueous solubility. Air sparging/soil vapor extraction is also successfully employed to treat MTBE, but its effectiveness is reduced by the low Henry's constant of MTBE. Sparging and other aerobic bioremediation approaches are hampered by the poor biodegradability of MTBE. Oxidation technologies, such as ozone injection, hold promise for rapid in situ remediation of MTBE. Treatment of recovered groundwater contaminated with MTBE is also problematic. MTBE adsorbs poorly to granular activated carbon; advanced oxidation processes are effective on MTBE, but entail high capital and operating costs; bioreactors are of questionable effectiveness on MTBE. Air stripping is usually the most cost-effective treatment technology for MTBE so long as the off gas from the air stripper can be discharged without treatment. However, off gas treatment is expensive, so groundwater is sometimes heated to reduce the requirement for stripping air

78 FR 31590 - Sears Holdings Management Corporation, A Division Of Sears Holdings Corporation, Hoffman Estates...

Science.gov (United States)

2013-05-24

... (``My position at Sears had nothing to do with Analytics or space Management. I worked in Marketing... firm clarified that one petitioner supplied print marketing management services, another petitioner... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-81,253] Sears Holdings Management...

effectiveness of technological options for minimising production risks

African Journals Online (AJOL)

ACSS

preferred technologies in reducing production risk related to climate variability in Eastern Uganda. Data for this study were ..... Set of technological options employed by farmers to reduce climate-induced production risk. Dummy = 1 if farmer. 0.71. 0.46 ..... cation exchange capacity for holding nutrients against leaching loss.

Nano technologies, technologies converging and potential biomedical applications

International Nuclear Information System (INIS)

Capuano, V.

2005-01-01

The applications of nano technology to biology and medicine appear really promising for diagnostics, for various therapeutic approaches and in medical instrumentations. The growing synergism among nano technology, biotechnology, information technology and cognitive sciences, their convergence (NBIC) from the nano scale, could involve on next decades great changes in medicine, from a reactive to a predictive and preventive approach. It is expected that NBIC converging technologies could achieve tremendous improvements in human abilities and enhance societal achievement of related social and ethical implications, in the framework of a constant dialogue between science and society [it

The Capability to Hold Property

NARCIS (Netherlands)

Claassen, Rutger

2015-01-01

This paper discusses the question of whether a capability theory of justice (such as that of Martha Nussbaum) should accept a basic “capability to hold property.” Answering this question is vital for bridging the gap between abstract capability theories of justice and their institutional

Teacher candidates in an online post-baccalaureate science methods course: Implications for teaching science inquiry with technology

Science.gov (United States)

Colon, Erica L.

programs hold promise for teacher candidates by providing them knowledge and strategies for implementing innovative technologies to teach science inquiry when designing curriculum. By identifying specific implications for methods course design and implementation, as well as future research, this study contributes to teacher education improvement efforts, and therefore supports changing learning styles of their future students, so-called the iGeneration.

C-14/I-29 Preservation and Hold Time Survey

Energy Technology Data Exchange (ETDEWEB)

Kitchen, S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2015-04-08

Preservation and hold time of radionuclides must account for both nuclear half-lives and nonnuclear loss mechanisms, but variations in the latter are often neglected. Metals-based defaults are inappropriate for long-lived non-metals C-14 and I-129, which are vulnerable to chemical and biological volatilization. Non-acidification is already widely practiced for them. Recommended addition measures from radiological and chemical literature include glass containers where possible, water filtration where possible, headspace minimization, light shielding, cold (4°C) storage and unfiltered water hold time of 28 days. Soil hold time may need to be shortened when water-logged, excessively sandy, or still adjusting to significant new contamination.

Anesthesia for robotic cardiac surgery: An amalgam of technology and skill

Directory of Open Access Journals (Sweden)

Chauhan Sandeep

2010-01-01

Full Text Available The surgical procedures performed with robtic assitance and the scope for its future assistance is endless. To keep pace with the developing technologies in this field it is imperative for the cardiac anesthesiologists to have aworking knowledge of these systems, recognize potential complications and formulate an anesthetic plan to provide safe patient care. Challenges posed by the use of robotic systems include, long surgical times, problems with one lung anesthesia in presence of coronary artery disease, minimally invasive percutaneous cardiopulmonary bypass management and expertise in Trans-Esophageal Echocardiography. A long list of cardiac surgeries are performed with the use of robotic assistance, and the list is continuously growing as surgical innovation crosses new boundaries. Current research in robotic cardiac surgery like beating heart off pump intracardic repair, prototype epicardial crawling device, robotic fetal techniques etc. are in the stage of animal experimentation, but holds a lot of promise in future

Promising More Information

Science.gov (United States)

2003-01-01

When NASA needed a real-time, online database system capable of tracking documentation changes in its propulsion test facilities, engineers at Stennis Space Center joined with ECT International, of Brookfield, Wisconsin, to create a solution. Through NASA's Dual-Use Program, ECT developed Exdata, a software program that works within the company's existing Promise software. Exdata not only satisfied NASA s requirements, but also expanded ECT s commercial product line. Promise, ECT s primary product, is an intelligent software program with specialized functions for designing and documenting electrical control systems. An addon to AutoCAD software, Promis e generates control system schematics, panel layouts, bills of material, wire lists, and terminal plans. The drawing functions include symbol libraries, macros, and automatic line breaking. Primary Promise customers include manufacturing companies, utilities, and other organizations with complex processes to control.

iPad versus Handwriting: Pilot Study Exploring the Writing Abilities of Students with Learning Disabilities

Science.gov (United States)

Corkett, Julie K.; Benevides, Tina

2016-01-01

Written expression is an essential skill to actively function in today's society. For many learners, especially those with a learning disability (LD), writing can be a source of frustration. Technology in its various forms, holds promise to assist students in this area. The current study examines the role that tablet technology, specifically,…

Research-practice interactions as reported in recent design research studies: Still promising, still hazy

NARCIS (Netherlands)

Ormel, Bart; Pareja Roblin, Natalie; McKenney, Susan; Voogt, Joke; Pieters, Jules

2012-01-01

Ormel, B., Pareja Roblin, N., McKenney, S., Voogt, J., & Pieters, J. (2012). Research-practice interactions as reported in recent design research studies: Still promising, still hazy. Educational Technology Research & Development, 60(6), 967-986. doi:10.1007/s11423-012-9261-6

Estimating animal movement contacts between holdings of different production types.

Science.gov (United States)

Lindström, Tom; Sisson, Scott A; Lewerin, Susanna Stenberg; Wennergren, Uno

2010-06-01

Animal movement poses a great risk for disease transmission between holdings. Heterogeneous contact patterns are known to influence the dynamics of disease transmission and should be included in modeling. Using pig movement data from Sweden as an example, we present a method for quantification of between holding contact probabilities based on different production types. The data contained seven production types: Sow pool center, Sow pool satellite, Farrow-to-finish, Nucleus herd, Piglet producer, Multiplying herd and Fattening herd. The method also estimates how much different production types will determine the contact pattern of holdings that have more than one type. The method is based on Bayesian analysis and uses data from central databases of animal movement. Holdings with different production types are estimated to vary in the frequency of contacts as well as in what type of holding they have contact with, and the direction of the contacts. Movements from Multiplying herds to Sow pool centers, Nucleus herds to other Nucleus herds, Sow pool centers to Sow pool satellites, Sow pool satellites to Sow pool centers and Nucleus herds to Multiplying herds were estimated to be most common relative to the abundance of the production types. We show with a simulation study that these contact patterns may also be expected to result in substantial differences in disease transmission via animal movements, depending on the index holding. Simulating transmission for a 1 year period showed that the median number of infected holdings was 1 (i.e. only the index holding infected) if the infection started at a Fattening herd and 2161 if the infection started on a Nucleus herd. We conclude that it is valuable to include production types in models of disease transmission and the method presented in this paper may be used for such models when appropriate data is available. We also argue that keeping records of production types is of great value since it may be helpful in risk

An inventory model of instantaneous deteriorating items with controllable deterioration rate for time dependent demand and holding cost

Directory of Open Access Journals (Sweden)

Vinod Kumar Mishra

2013-06-01

Full Text Available Purpose: The purpose of this paper to develop an inventory model for instantaneous deteriorating items with the consideration of the facts that the deterioration rate can be controlled by using the preservation technology (PT and the holding cost & demand rate both are linear function of time which was treated as constant in most of the deteriorating inventory model. Design/methodology/approach: Developed the mathematical equation of deterministic deteriorating inventory model in which demand rate and holding cost both is linear function of time, deterioration rate is constant, backlogging rate is variable and depend on the length of the next replenishment, shortages are allowed and partially backlogged and obtain an analytical solution which optimizes the total cost of the proposed inventory model. Findings: The model can be applied for optimizing the total inventory cost of deteriorating items inventory for such business enterprises where they use the preservation technology to control the deterioration rate under other assumptions of the model. Originality/value: The inventory system for deteriorating items has been an object of study for a long time, but little is known about the effect of investing in reducing the rate of product deterioration and their significant impact in the business. The proposed model is effective as well as efficient for the business organization that uses the preservation technology to reduce the deterioration rate of the instantaneous deteriorating items of the inventory.

The carbon holdings of northern Ecuador's mangrove forests

OpenAIRE

Hamilton, Stuart E.; Lovette, John; Borbor, Mercy; Millones, Marco

2016-01-01

Within a GIS environment, we combine field measures of mangrove diameter, mangrove species distribution, and mangrove density with remotely sensed measures of mangrove location and mangrove canopy cover to estimate the mangrove carbon holdings of northern Ecuador. We find that the four northern estuaries of Ecuador contain approximately 7,742,999 t (plus or minus 15.47 percent) of standing carbon. Of particular high carbon holdings are the Rhizophora mangle dominated mangrove stands found in-...

Convergence and Spanish technological specialization: the role of multinational companies

International Nuclear Information System (INIS)

Urraca Ruiz, A.

2007-01-01

Using patent data from EPO from 1978 to 2003, this paper aims to identify the role of MNE in the determination of technological specialization trends and convergence in Spain and the extend to which the technological activity of these companies helps to define the technical distribution of competence in the country.The main findings are: (i) Spain reduces its technological distances to world along the whole period; (ii) Spanish convergence process does not seem to be accompanied by greater specialization, but greater diversification of its technological competence; (iii) Spain is specialized in a few technical fields characterized by being less dynamic and pervasive; (iv) MNE do not seem to hold strong competence in those technical fields where Spain holds technological strengths but do help to convergence process thought diversification of competence process, which is a consequence of the performance of MNE in host catching up countries, more focused on duplication of their home countries.(Author)

The climate technology initiative

International Nuclear Information System (INIS)

Smith, Adam

2000-01-01

The CTI (Climate Technology Initiative) aims to promote those technologies which cause the minimum of harm to the environment: reducing emissions of greenhouse gases and supporting those countries most vulnerable to climate change are priorities. A strong case for cogeneration is made and it is pointed out that both the European Union and the USA aim to double their cogeneration capacity by 2010. The CTI holds training courses and seminars all over the world where the barriers to the expansion of climate-friendly technology are discussed. The article also mentions the CTI Co-operation Technology Implementation Plan, research and development, its website and search engine, its presence at all UNFCCC events and its awards programme

The climate technology initiative

Energy Technology Data Exchange (ETDEWEB)

Smith, Adam [International Energy Agency, Climate Technology Initiative, Paris (France)

2000-12-01

The CTI (Climate Technology Initiative) aims to promote those technologies which cause the minimum of harm to the environment: reducing emissions of greenhouse gases and supporting those countries most vulnerable to climate change are priorities. A strong case for cogeneration is made and it is pointed out that both the European Union and the USA aim to double their cogeneration capacity by 2010. The CTI holds training courses and seminars all over the world where the barriers to the expansion of climate-friendly technology are discussed. The article also mentions the CTI Co-operation Technology Implementation Plan, research and development, its website and search engine, its presence at all UNFCCC events and its awards programme.

MBR technology: a promising approach for the (pre-)treatment of hospital wastewater.

Science.gov (United States)

Beier, S; Cramer, C; Mauer, C; Köster, S; Schröder, H Fr; Pinnekamp, J

2012-01-01

Membrane bioreactor (MBR) technology is a very reliable and extensively tested solution for biological wastewater treatment. Nowadays, separate treatment of highly polluted wastewater streams especially from hospitals and other health care facilities is currently under investigation worldwide. In this context, the MBR technology will play a decisive role because an effluent widely cleaned up from solids and nutrients is absolutely mandatory for a subsequent further elimination of organic trace pollutants. Taking hospital wastewater as an example, the aim of this study was to investigate to what extent MBR technology is an adequate 'pre-treatment' solution for further elimination of trace pollutants. Therefore, we investigated - within a 2-year period - the performance of a full-scale hospital wastewater treatment plant (WWTP) equipped with a MBR by referring to conventional chemical and microbiological standard parameters. Furthermore, we measured the energy consumption and tested different operating conditions. According to our findings the MBR treatment of the hospital wastewater was highly efficient in terms of the removal of solids and nutrients. Finally, we did not observe any major adverse effects on the operation and performance of the MBR system which potentially could derive from the composition of the hospital wastewater. In total, the present study proved that MBR technology is a very efficient and reliable treatment approach for the treatment of highly polluted wastewater from hospitals and can be recommended as a suitable pre-treatment solution for further trace pollutant removal.

Primary EFL Teachers' Technology Use in China: Patterns and Perceptions

Science.gov (United States)

Li, Guofang; Ni, Xiaopeng

2011-01-01

Drawing on survey data, this paper examines the patterns and perceptions of technology use by primary EFL teachers in China. Findings suggest that although Chinese EFL teachers hold positive attitudes toward the value of technology for teaching and learning, they use technology mainly for teacher-centered purposes, such as teaching preparation and…

Quantifying Neonatal Sucking Performance: Promise of New Methods.

Science.gov (United States)

Capilouto, Gilson J; Cunningham, Tommy J; Mullineaux, David R; Tamilia, Eleonora; Papadelis, Christos; Giannone, Peter J

2017-04-01

Neonatal feeding has been traditionally understudied so guidelines and evidence-based support for common feeding practices are limited. A major contributing factor to the paucity of evidence-based practice in this area has been the lack of simple-to-use, low-cost tools for monitoring sucking performance. We describe new methods for quantifying neonatal sucking performance that hold significant clinical and research promise. We present early results from an ongoing study investigating neonatal sucking as a marker of risk for adverse neurodevelopmental outcomes. We include quantitative measures of sucking performance to better understand how movement variability evolves during skill acquisition. Results showed the coefficient of variation of suck duration was significantly different between preterm neonates at high risk for developmental concerns (HRPT) and preterm neonates at low risk for developmental concerns (LRPT). For HRPT, results indicated the coefficient of variation of suck smoothness increased from initial feeding to discharge and remained significantly greater than healthy full-term newborns (FT) at discharge. There was no significant difference in our measures between FT and LRPT at discharge. Our findings highlight the need to include neonatal sucking assessment as part of routine clinical care in order to capture the relative risk of adverse neurodevelopmental outcomes at discharge. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

The Design of Bulk Carrier Cargo Holds State Integrated Monitoring System

Directory of Open Access Journals (Sweden)

Gao Ru-jiang

2016-01-01

Full Text Available Most ship cargo hold Internal uses artificial watch or is unattended. Therefore, it is impossible to know the appropriate information of the cargo holds Internal timely and accurately. Cargo damage and ship accidents occurred frequently. Automation remote processing and monitoring alarm system for the bulk carrier is an important part of the marine automation. The system plays a significant role to guarantee the navigation safety for bulk carriers. The paper introduced the important parts of the integrated monitoring system, structural design, hardware configuration, various modules communication transmission and various data processing software design were included. Based on embedded development, the real time information including the cargo hold internal humidity temperature, oxygen concentration, smoke gas concentration, cold water well level and other data were collected, as well the hatch closed state was detected and the cargo hold internal real time video information was collected. Then the real-time communication between the control display and acquisition modules were assured. By adjusting the corresponding buttons on the bridge according to the monitoring information, so that the cargo hold always in a safe environment, so as to avoid cargo hold accidents.

High dimensional biological data retrieval optimization with NoSQL technology

Science.gov (United States)

2014-01-01

Background High-throughput transcriptomic data generated by microarray experiments is the most abundant and frequently stored kind of data currently used in translational medicine studies. Although microarray data is supported in data warehouses such as tranSMART, when querying relational databases for hundreds of different patient gene expression records queries are slow due to poor performance. Non-relational data models, such as the key-value model implemented in NoSQL databases, hold promise to be more performant solutions. Our motivation is to improve the performance of the tranSMART data warehouse with a view to supporting Next Generation Sequencing data. Results In this paper we introduce a new data model better suited for high-dimensional data storage and querying, optimized for database scalability and performance. We have designed a key-value pair data model to support faster queries over large-scale microarray data and implemented the model using HBase, an implementation of Google's BigTable storage system. An experimental performance comparison was carried out against the traditional relational data model implemented in both MySQL Cluster and MongoDB, using a large publicly available transcriptomic data set taken from NCBI GEO concerning Multiple Myeloma. Our new key-value data model implemented on HBase exhibits an average 5.24-fold increase in high-dimensional biological data query performance compared to the relational model implemented on MySQL Cluster, and an average 6.47-fold increase on query performance on MongoDB. Conclusions The performance evaluation found that the new key-value data model, in particular its implementation in HBase, outperforms the relational model currently implemented in tranSMART. We propose that NoSQL technology holds great promise for large-scale data management, in particular for high-dimensional biological data such as that demonstrated in the performance evaluation described in this paper. We aim to use this new data

High dimensional biological data retrieval optimization with NoSQL technology.

Science.gov (United States)

Wang, Shicai; Pandis, Ioannis; Wu, Chao; He, Sijin; Johnson, David; Emam, Ibrahim; Guitton, Florian; Guo, Yike

2014-01-01

High-throughput transcriptomic data generated by microarray experiments is the most abundant and frequently stored kind of data currently used in translational medicine studies. Although microarray data is supported in data warehouses such as tranSMART, when querying relational databases for hundreds of different patient gene expression records queries are slow due to poor performance. Non-relational data models, such as the key-value model implemented in NoSQL databases, hold promise to be more performant solutions. Our motivation is to improve the performance of the tranSMART data warehouse with a view to supporting Next Generation Sequencing data. In this paper we introduce a new data model better suited for high-dimensional data storage and querying, optimized for database scalability and performance. We have designed a key-value pair data model to support faster queries over large-scale microarray data and implemented the model using HBase, an implementation of Google's BigTable storage system. An experimental performance comparison was carried out against the traditional relational data model implemented in both MySQL Cluster and MongoDB, using a large publicly available transcriptomic data set taken from NCBI GEO concerning Multiple Myeloma. Our new key-value data model implemented on HBase exhibits an average 5.24-fold increase in high-dimensional biological data query performance compared to the relational model implemented on MySQL Cluster, and an average 6.47-fold increase on query performance on MongoDB. The performance evaluation found that the new key-value data model, in particular its implementation in HBase, outperforms the relational model currently implemented in tranSMART. We propose that NoSQL technology holds great promise for large-scale data management, in particular for high-dimensional biological data such as that demonstrated in the performance evaluation described in this paper. We aim to use this new data model as a basis for migrating

Emerging educational technologies: Tensions and synergy

Directory of Open Access Journals (Sweden)

J. Michael Spector

2014-01-01

Full Text Available A review of high level sources with regard to new and emerging technologies was conducted. Three technologies, according to these sources, appear especially promising: (a massive open online courses (MOOCs, (b personalized learning, and (c game-based learning. This paper will review information from the US National Science Foundation, the US Department of Education, the New Media Consortium, and two European Networks of Excellence with regard to new and emerging technologies. A critique will then be provided using established principles pertaining to learning and instruction and a recommended curriculum for advanced learning technologies. The general result is that it appears that some educational technology advocates are overstating the likelihood of these three technologies having a significant and sustained impact in the near future, although there are promising aspects to each of these technologies in the long term.

The performance and risk of Hartalega Holdings Berhad

OpenAIRE

Wong, Kah Wai

2017-01-01

The purpose of the study is to investigate the overall performance of Hartalega Holdings Berhad and specific risk factors and macroeconomic factors are influence on profitability performance. The data obtained from annual report of Hartalega Holdings Berhad during the years 2011 to 2015. The measurement of financial ratios and regression analysis used to see the overall performance and risk of the company. The study found that performance of the company is unfavourable due to the decreasing m...

Sugar and Spice and Science: Encouraging Girls through Media Mentoring

Science.gov (United States)

Gray, Jennifer B.

2005-01-01

Studies indicate that long held gender stereotypes lead females to a decreased self-confidence and interest in the sciences. As a result, only a minority of women pursue coursework and careers in science and technology-based fields. Several gender-based studies in science and technology education indicate that mentoring may hold great promise in…

Climate change and eHealth: a promising strategy for health sector mitigation and adaptation

Directory of Open Access Journals (Sweden)

Åsa Holmner

2012-06-01

Full Text Available Climate change is one of today's most pressing global issues. Policies to guide mitigation and adaptation are needed to avoid the devastating impacts of climate change. The health sector is a significant contributor to greenhouse gas emissions in developed countries, and its climate impact in low-income countries is growing steadily. This paper reviews and discusses the literature regarding health sector mitigation potential, known and hypothetical co-benefits, and the potential of health information technology, such as eHealth, in climate change mitigation and adaptation. The promising role of eHealth as an adaptation strategy to reduce societal vulnerability to climate change, and the link's between mitigation and adaptation, are also discussed. The topic of environmental eHealth has gained little attention to date, despite its potential to contribute to more sustainable and green health care. A growing number of local and global initiatives on ‘green information and communication technology (ICT’ are now mentioning eHealth as a promising technology with the potential to reduce emission rates from ICT use. However, the embracing of eHealth is slow because of limitations in technological infrastructure, capacity and political will. Further research on potential emissions reductions and co-benefits with green ICT, in terms of health outcomes and economic effectiveness, would be valuable to guide development and implementation of eHealth in health sector mitigation and adaptation policies.

Climate change and eHealth: a promising strategy for health sector mitigation and adaptation

Science.gov (United States)

Holmner, Åsa; Rocklöv, Joacim; Ng, Nawi; Nilsson, Maria

2012-01-01

Climate change is one of today's most pressing global issues. Policies to guide mitigation and adaptation are needed to avoid the devastating impacts of climate change. The health sector is a significant contributor to greenhouse gas emissions in developed countries, and its climate impact in low-income countries is growing steadily. This paper reviews and discusses the literature regarding health sector mitigation potential, known and hypothetical co-benefits, and the potential of health information technology, such as eHealth, in climate change mitigation and adaptation. The promising role of eHealth as an adaptation strategy to reduce societal vulnerability to climate change, and the link's between mitigation and adaptation, are also discussed. The topic of environmental eHealth has gained little attention to date, despite its potential to contribute to more sustainable and green health care. A growing number of local and global initiatives on ‘green information and communication technology (ICT)’ are now mentioning eHealth as a promising technology with the potential to reduce emission rates from ICT use. However, the embracing of eHealth is slow because of limitations in technological infrastructure, capacity and political will. Further research on potential emissions reductions and co-benefits with green ICT, in terms of health outcomes and economic effectiveness, would be valuable to guide development and implementation of eHealth in health sector mitigation and adaptation policies. PMID:22679398

The future of fully automated vehicles : opportunities for vehicle- and ride-sharing, with cost and emissions savings.

Science.gov (United States)

2014-08-01

Fully automated or autonomous vehicles (AVs) hold great promise for the future of transportation. By 2020 : Google, auto manufacturers and other technology providers intend to introduce self-driving cars to the public with : either limited or fully a...

Cell Surface and Membrane Engineering: Emerging Technologies and Applications

Directory of Open Access Journals (Sweden)

Christopher T. Saeui

2015-06-01

Full Text Available Membranes constitute the interface between the basic unit of life—a single cell—and the outside environment and thus in many ways comprise the ultimate “functional biomaterial”. To perform the many and often conflicting functions required in this role, for example to partition intracellular contents from the outside environment while maintaining rapid intake of nutrients and efflux of waste products, biological membranes have evolved tremendous complexity and versatility. This article describes how membranes, mainly in the context of living cells, are increasingly being manipulated for practical purposes with drug discovery, biofuels, and biosensors providing specific, illustrative examples. Attention is also given to biology-inspired, but completely synthetic, membrane-based technologies that are being enabled by emerging methods such as bio-3D printers. The diverse set of applications covered in this article are intended to illustrate how these versatile technologies—as they rapidly mature—hold tremendous promise to benefit human health in numerous ways ranging from the development of new medicines to sensitive and cost-effective environmental monitoring for pathogens and pollutants to replacing hydrocarbon-based fossil fuels.

Cell Surface and Membrane Engineering: Emerging Technologies and Applications

Science.gov (United States)

Saeui, Christopher T.; Mathew, Mohit P.; Liu, Lingshui; Urias, Esteban; Yarema, Kevin J.

2015-01-01

Membranes constitute the interface between the basic unit of life—a single cell—and the outside environment and thus in many ways comprise the ultimate “functional biomaterial”. To perform the many and often conflicting functions required in this role, for example to partition intracellular contents from the outside environment while maintaining rapid intake of nutrients and efflux of waste products, biological membranes have evolved tremendous complexity and versatility. This article describes how membranes, mainly in the context of living cells, are increasingly being manipulated for practical purposes with drug discovery, biofuels, and biosensors providing specific, illustrative examples. Attention is also given to biology-inspired, but completely synthetic, membrane-based technologies that are being enabled by emerging methods such as bio-3D printers. The diverse set of applications covered in this article are intended to illustrate how these versatile technologies—as they rapidly mature—hold tremendous promise to benefit human health in numerous ways ranging from the development of new medicines to sensitive and cost-effective environmental monitoring for pathogens and pollutants to replacing hydrocarbon-based fossil fuels. PMID:26096148

Augmented Reality in Science Education

DEFF Research Database (Denmark)

Nielsen, Birgitte Lund; Brandt, Harald; Swensen, Hakon

Augmented reality (AR) holds great promise as a learning tool. However, most extant studies in this field have focused on the technology itself. The poster presents findings from the first stage of the AR-sci project addressing the issue of applying AR for educational purposes. Benefits and chall......Augmented reality (AR) holds great promise as a learning tool. However, most extant studies in this field have focused on the technology itself. The poster presents findings from the first stage of the AR-sci project addressing the issue of applying AR for educational purposes. Benefits...... and challenges related to AR enhancing student learning in science in lower secondary school were identified by expert science teachers, ICT designers and science education researchers from four countries in a Delphi survey. Findings were condensed in a framework to categorize educational AR designs....

Determinants of corporate cash holdings: Evidence from Portuguese publicly traded firms

Directory of Open Access Journals (Sweden)

Fernandes, Filipa

2017-05-01

Full Text Available This paper investigates the determinants of cash holdings of publicly traded Portuguese firms. We find that such firms hold less cash than similar companies operating in countries where both shareholders and creditors’ rights are more tightly protected by the law. In addition, our regression results suggest that leverage, other liquid assets, and firm growth are negatively correlated with our sample firms’ cash holdings whereas long-term debt and financial distress are positively correlated. Our findings cannot be reconciled with just one of the existent theories (trade-off, pecking order and free cashflow theory, and emphasize the importance of a country’s legal, institutional, and economic environment for explaining firms’ cash holdings decisions.

FUNCTIONING OF AGRICULTURAL HOLDINGS IN UKRAINE: STRONG AND WEAK SIDES

Directory of Open Access Journals (Sweden)

Postgraduate, assistant Sergii Ivanovich TODORIUK

2014-06-01

Full Text Available One of the organizational forms of the agricultural management which is gaining popularity in the world is agricultural holdings. The essence of agricultural holdings is considered in the article. Also the peculiarities of their functioning in Ukraine and determination of the strengths and weaknesses of their activities is defined, as well as perspectives of their further functioning. Agrarian holding, as a relatively new organizational legal form of managing in Ukraine has its advantages and disadvantages. As the experience shows the advantages of agrarian holdings over the subjects of management are revealed mainly in the economic sphere. While their disadvantages over the subjects of management are revealed in social and ecological spheres. This is a negative moment considering the implementation in Ukraine of the concept of the sustainable development, which means the combination of these main components (economic component, environmental component, social component.

Watch IT: The Risks and Promises of Information Technologies for Education.

Science.gov (United States)

Burbules, Nicholas C.; Callister, Thomas A., Jr.

This book is an examination of several critical issues and controversies concerning the potential of new information technology (IT) for education. In a series of interrelated essays, the book explores such issues as access, credibility, new approaches to reading and writing, the glut of information, privacy, censorship, commercialization, and…

Control of cooperative manipulators in holding deformable objects

Science.gov (United States)

Alkathiri, A. A.; Azlan, N. Z.

2017-11-01

This paper presents the implementation of a control system to control cooperative manipulators to hold deformable objects. The aim is to hold the deformable object without having information on the shape and stiffness of the deformable object beforehand. The prototype of a pair of manipulators has been designed and built to test the controller. A force sensor and a rotary encoder are used to give feedback to the controller, which controls the DC motor actuators accordingly. A position proportional-integral-derivative (PID) controller technique has been applied for one of the manipulators and a PID force control technique is applied to the other. Simulations and experimental tests have been conducted on models and the controller has been implemented on the real plant. Both simulation and test results prove that the implemented control technique has successfully provided the desired position and force to hold the deformable object with maximum experimental errors of 0.34mm and 50mN respectively.

Immobilization of biocatalysts for enzymatic polymerizations : Possibilities, advantages, applications

NARCIS (Netherlands)

Miletic, Nemanja; Nastasovic, Aleksandra; Loos, Katja; Miletić, Nemanja; Nastasović, Aleksandra

Biotechnology also holds tremendous opportunities for realizing functional polymeric materials. Biocatalytic pathways to polymeric materials are an emerging research area with not only enormous scientific and technological promise, but also a tremendous impact on environmental issues. Many of the

The effect of three holding tank chemicals on anaerobic wastewater treatment

OpenAIRE

Howard, Samuel Clarence

1988-01-01

Sewage-holding tanks aboard recreational boats store human wastes, thereby preventing the direct discharge of wastewater to the aquatic environment. Water-conserving toilets and limited holding tank volumes produce a highly concentrated waste that must be periodically dumped to a wastewater treatment system. Prior to disposal, many boat operators add commercial preparations to control odors produced in their chemical toilets and holding tanks. The objective of this study was to determine t...

Technology transfer

International Nuclear Information System (INIS)

Anon.

1977-01-01

Illustrated by the example of the FRG's nuclear energy exports, it is shown that the nuclear technology transfer leads to new dimensions of intergovernmental relations, which hold within themselves on account of multiple state-to-state, scientific, industrial and - last but not least - personal contacts the chance of far-reaching friendships between countries and people. If the chance is taken, this can also be seen as an important contribution towards maintaining the peace. (orig.) [de

Promises and pitfalls of NGS technology in Clinic: Experience from Kolkata

Directory of Open Access Journals (Sweden)

Atanu Kumar Dutta

2017-12-01

With the help of a series of cases the utility of NGS testing and different flavors of the technology will be outlined. Specifically in the prenatal diagnostic setting dilemma related to testing and not testing will be outlined. The absence of customized CNV assays complimenting the NGS panel will be highlighted.

12 CFR 584.4 - Certain acquisitions by savings and loan holding companies.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Certain acquisitions by savings and loan... TREASURY SAVINGS AND LOAN HOLDING COMPANIES § 584.4 Certain acquisitions by savings and loan holding companies. (a) Acquisitions by a savings and loan holding company of more than five percent of a non...

Technology-Enhanced Formative Assessment: A Research-Based Pedagogy for Teaching Science with Classroom Response Technology

Science.gov (United States)

Beatty, Ian D.; Gerace, William J.

2009-01-01

"Classroom response systems" (CRSs) are a promising instructional technology, but most literature on CRS use fails to distinguish between technology and pedagogy, to define and justify a pedagogical perspective, or to discriminate between pedagogies. "Technology-enhanced formative assessment" (TEFA) is our pedagogy for CRS-based science…

SOIL VAPOR EXTRACTION TECHNOLOGY: REFERENCE HANDBOOK

Science.gov (United States)

Soil vapor extraction (SVE) systems are being used in Increasing numbers because of the many advantages these systems hold over other soil treatment technologies. SVE systems appear to be simple in design and operation, yet the fundamentals governing subsurface vapor transport ar...

Why not stop transfer of technology

Energy Technology Data Exchange (ETDEWEB)

Baumer, J M

1979-01-01

One of the crucial themes in the dialogue between rich and poor nations is the nature and volume of the transfer of technology from the industrialized to the developing world. In contrast to the demand of overcoming the technology gap, Prof. Baumer argues that the postulate should rather be formulated as reduction of technological dependence. Industrialized countries say without technology, there is no growth; they say modern technology is the right technology. They are indeed against a cutting of costs and basically against simplifying the getting hold of their technology. Of prime importance is the development of technology at the site of the problems themselves. Problems can be solved in technically quite different ways - from simple to very complicated - and drawer-technology is only in the rarest cases the best solution. (MCW)

High-yield growth and characterization of ⟨100⟩ InP p−n diode nanowires

NARCIS (Netherlands)

Cavalli, A.; Wang, J.; Zadeh, I.E.; Reimer, M.E.; Verheijen, M.A.; Soini, M.; Plissard, S.R.; Zwiller, V.; Haverkort, J.E.M.; Bakkers, E.P.A.M.

2016-01-01

Semiconductor nanowires are nanoscale structures holding promise in many fields such as optoelectronics, quantum computing, and thermoelectrics. Nanowires are usually grown vertically on (111)-oriented substrates, while (100) is the standard in semiconductor technology. The ability to grow and to

Enhanced multimedia content access and exploitation using semantic speech retrieval

NARCIS (Netherlands)

Ordelman, Roeland J.F.; de Jong, Franciska M.G.; Larson, Martha

Techniques for automatic annotation of spoken content making use of speech recognition technology have long been characterized as holding unrealized promise to provide access to archives inundated with undisclosed multimedia material. This paper provides an overview of techniques and trends in

Whitepaper on New Localization Methods for 5G Wireless Systems and the Internet-of-Things

DEFF Research Database (Denmark)

Pedersen, Troels; Fleury, Bernard Henri

2018-01-01

Disruptive technologies proposed for 5G wireless systems and the IoT hold promise of providing unprecedented localization capabilities for a wide range of application scenarios and target environments. This whitepaper summarizes the expected features and resulting properties of upcoming localizat...

Stem cell therapy: the great promise in lung disease.

Science.gov (United States)

Siniscalco, Dario; Sullo, Nikol; Maione, Sabatino; Rossi, Francesco; D'Agostino, Bruno

2008-06-01

Lung injuries are leading causes of morbidity and mortality worldwide. Pulmonary diseases such as asthma or chronic obstructive pulmonary disease characterized by loss of lung elasticity, small airway tethers, and luminal obstruction with inflammatory mucoid secretions, or idiopathic pulmonary fibrosis characterized by excessive matrix deposition and destruction of the normal lung architecture, have essentially symptomatic treatments and their management is costly to the health care system.Regeneration of tissue by stem cells from endogenous, exogenous, and even genetically modified cells is a promising novel therapy. The use of adult stem cells to help with lung regeneration and repair could be a newer technology in clinical and regenerative medicine. In fact, different studies have shown that bone marrow progenitor cells contribute to repair and remodeling of lung in animal models of progressive pulmonary hypertension.Therefore, lung stem cell biology may provide novel approaches to therapy and could represent a great promise for the future of molecular medicine. In fact, several diseases can be slowed or even blocked by stem cell transplantation.

Giving up Technology and Social Media: Why University Lecturers Stop Using Technology in Teaching

Science.gov (United States)

Shelton, Chris

2017-01-01

University lecturers use a wide range of technologies when teaching and there has been much research into how particular technologies are adopted. However, there are also many technologies that, despite early promise, are no longer being used in university teaching and have been abandoned by institutions or individuals. This article presents the…

Holding a candle to innovation in concentrating solar power technologies: A study drawing on patent data

International Nuclear Information System (INIS)

Braun, Frauke G.; Hooper, Elizabeth; Wand, Robert; Zloczysti, Petra

2011-01-01

Improved understanding of the innovative pathways of renewable energy technologies is vital if we are to make the transition to a low carbon economy. This study presents new evidence on innovation and industry dynamics in concentrating solar power (CSP) technologies. Though CSP is undergoing a renaissance, existing innovation studies have explored innovative activity in solar technologies in general, ignoring the major differences between solar photovoltaic and CSP technologies. This study, based on patent data, examines the level and dynamics of innovative activity in CSP between 1978 and 2004. Our unique contribution, based on engineering expertise and detailed datawork, is a classification system mapping CSP technologies to the International Patent Classification (IPC) system. The innovation performance of CSP is found to be surprisingly weak compared to the patent boom in other green technologies. Performance was strong around 1980 before falling dramatically, and has only recently begun to show signs of recovery. Innovation and R and D are concentrated in high-tech countries; the US, Germany and Japan, which do not necessarily have high domestic CSP potential. Large CSP potential is, therefore, not a sufficient condition for innovation. Innovators must possess economic and scientific capabilities. - Research highlights: → We develop a new classification system which allows us to map innovation in CSP technologies to the International Patent Classification System. → Evidence of innovation patterns in concentrating solar power technologies is presented. → Innovation performance in CSP is surprisingly weak compared to patenting in other green technologies, despite its strong potential as a low carbon power generation technology.

Technologies for Collaborative Business Process Management

NARCIS (Netherlands)

Sadiq, Shazia; Reichert, M.U.; Schulz, Karsten

Business process management (BPM) has become an extensive area of research with several specialized aspects. BPM is viewed from highly diverse angles ranging from a management strategy to a software system. It is widely acknowledged that process enforcement technologies hold the potential to provide

High voltage holding in the negative ion sources with cesium deposition

Energy Technology Data Exchange (ETDEWEB)

Belchenko, Yu.; Abdrashitov, G.; Ivanov, A.; Sanin, A.; Sotnikov, O., E-mail: O.Z.Sotnikov@inp.nsk.su [Budker Institute of Nuclear Physics, Siberian Branch of Russian Academy of Sciences, Novosibirsk (Russian Federation)

2016-02-15

High voltage holding of the large surface-plasma negative ion source with cesium deposition was studied. It was found that heating of ion-optical system electrodes to temperature >100 °C facilitates the source conditioning by high voltage pulses in vacuum and by beam shots. The procedure of electrode conditioning and the data on high-voltage holding in the negative ion source with small cesium seed are described. The mechanism of high voltage holding improvement by depletion of cesium coverage is discussed.

Holding-time-aware asymmetric spectrum allocation in virtual optical networks

Science.gov (United States)

Lyu, Chunjian; Li, Hui; Liu, Yuze; Ji, Yuefeng

2017-10-01

Virtual optical networks (VONs) have been considered as a promising solution to support current high-capacity dynamic traffic and achieve rapid applications deployment. Since most of the network services (e.g., high-definition video service, cloud computing, distributed storage) in VONs are provisioned by dedicated data centers, needing different amount of bandwidth resources in both directions, the network traffic is mostly asymmetric. The common strategy, symmetric provisioning of traffic in optical networks, leads to a waste of spectrum resources in such traffic patterns. In this paper, we design a holding-time-aware asymmetric spectrum allocation module based on SDON architecture and an asymmetric spectrum allocation algorithm based on the module is proposed. For the purpose of reducing spectrum resources' waste, the algorithm attempts to reallocate the idle unidirectional spectrum slots in VONs, which are generated due to the asymmetry of services' bidirectional bandwidth. This part of resources can be exploited by other requests, such as short-time non-VON requests. We also introduce a two-dimensional asymmetric resource model for maintaining idle spectrum resources information of VON in spectrum and time domains. Moreover, a simulation is designed to evaluate the performance of the proposed algorithm, and results show that our proposed asymmetric spectrum allocation algorithm can improve the resource waste and reduce blocking probability.

12 CFR 584.2a - Exempt savings and loan holding companies and grandfathered activities.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Exempt savings and loan holding companies and... THE TREASURY SAVINGS AND LOAN HOLDING COMPANIES § 584.2a Exempt savings and loan holding companies and grandfathered activities. (a) Exempt savings and loan holding companies. (1) The following savings and loan...

In vitro holding and PLD-repair. Pt. 2

International Nuclear Information System (INIS)

Stevenson, A.F.G.; Palackal, T.; Lange, C.S.

1989-01-01

The repair of potentially lethal damage (PLDR) in mammalian cells is expected to be better in quiescent cultures since PLD is supposedly fixed during cycle progression. Plateau phase cultures, therefore, serve as models because of assumed mitotic quiescence. Four established cell lines (V79, CHO, L5178Y and HELA) and one euploid cell strain IMR-90 have been analysed by flow cytometry and electron microscopy to address questions on quiescence in the plateau phase and the effect of holding (induction of quiescence by nutrient privation). In contrast to commonly held views, our results indicate that the quiescent fraction in cultures from transformed cells is exceedingly low (1% or less). Plateau phase cultures of transformed cells are constantly turning over. Euploid cells like the IMR-90 show true quiescence in the plateau phase. Holding causes typical cytopathological changes. These changes have been ultrastructurely characterised. Resistant sub-populations of cells can be selected out under holding-conditions. Such selected cells show completely different radiobiological characteristics, which raise questions on the interpretation of data on PLDR. (orig.)

Probe-holding apparatus for holding a probe for checking steam generator tubes particularly in a nuclear reactor installation

International Nuclear Information System (INIS)

Adamowski, A.; Gagny; Gallet, G.; Lhermitte, J.; Monne, M.; Vautherot, G.

1984-01-01

Probe-holding apparatus for holding a probe for checking steam generator tubes particularly in a nuclear reactor installation. The apparatus comprises a telescopic arm supported via a ball and socket joint from a support mounted in or near an access aperture in a chamber at one end of the steam generator. A probe guide is carried by a carriage pivotally mounted at the other end of the telescopic arm. The carriage includes an endless belt having a series of spaced projections which engage into the ends of the tubes, the projections being spaced by a distance equal to the tube pitch or a multiple thereof. The belt is driven by a stepping motor in order to move the carriage and place the probe guide opposite different ones of the tubes

Quality Assurance Challenges for Motion-Adaptive Radiation Therapy: Gating, Breath Holding, and Four-Dimensional Computed Tomography

International Nuclear Information System (INIS)

Jiang, Steve B.; Wolfgang, John; Mageras, Gig S.

2008-01-01

Compared with conventional three-dimensional (3D) conformal radiation therapy and intensity-modulated radiation therapy treatments, quality assurance (QA) for motion-adaptive radiation therapy involves various challenges because of the added temporal dimension. Here we discuss those challenges for three specific techniques related to motion-adaptive therapy: namely respiratory gating, breath holding, and four-dimensional computed tomography. Similar to the introduction of any other new technologies in clinical practice, typical QA measures should be taken for these techniques also, including initial testing of equipment and clinical procedures, as well as frequent QA examinations during the early stage of implementation. Here, rather than covering every QA aspect in depth, we focus on some major QA challenges. The biggest QA challenge for gating and breath holding is how to ensure treatment accuracy when internal target position is predicted using external surrogates. Recommended QA measures for each component of treatment, including simulation, planning, patient positioning, and treatment delivery and verification, are discussed. For four-dimensional computed tomography, some major QA challenges have also been discussed

Reflections on the Development of a Machine Vision Technology for the Forest Products

Science.gov (United States)

Richard W. Conners; D.Earl Kline; Philip A. Araman; Robert L. Brisbon

1992-01-01

The authors have approximately 25 years experience in developing machine vision technology for the forest products industry. Based on this experience this paper will attempt to realistically predict what the future holds for this technology. In particular, this paper will attempt to describe some of the benefits this technology will offer, describe how the technology...

Visualizing Chemistry: The Progess and Promise of Advanced Chemical Imaging

Energy Technology Data Exchange (ETDEWEB)

Committee on Revealing Chemistry Through Advanced Chemical Imaging

2006-09-01

The field of chemical imaging can provide detailed structural, functional, and applicable information about chemistry and chemical engineering phenomena that have enormous impacts on medicine, materials, and technology. In recognizing the potential for more research development in the field of chemical imaging, the National Academies was asked by the National Science Foundation, Department of Energy, U.S. Army, and National Cancer Institute to complete a study that would review the current state of molecular imaging technology, point to promising future developments and their applications, and suggest a research and educational agenda to enable breakthrough improvements in the ability to image molecular processes simultaneously in multiple physical dimensions as well as time. The study resulted in a consensus report that provides guidance for a focused research and development program in chemical imaging and identifies research needs and possible applications of imaging technologies that can provide the breakthrough knowledge in chemistry, materials science, biology, and engineering for which we should strive. Public release of this report is expected in early October.

The Promise of E-Platform Technology in Medical Education.

Science.gov (United States)

Dawd, Siraj

2016-03-01

Increasing the number as well as improving the capacity and quality of medical professionals to achieve an equitable health care for all is a global priority and a global challenge. In developing countries, which are facing the largest burden of disease, to achieve the above stated objective, there is a big need for more well-trained, competent and dedicated health care providers. Currently, there is a well-documented shortage of trained health workers globally, with the poorest countries having the greatest shortfalls. The time tested, traditional approach of training health care force by importing professionals from overseas is not only prohibitively expensive but also not sufficient to achieve the scale and pace of the required human capacity building. Considering this fact, distance learning programs, which include m-Health as well as other information technology (IT) platforms and tools, can provide unique, timely, cost-effective, easily scalable and valuable opportunities to expand access to training health care manpower in developing countries where the shortage is critical.

Microbial fuel cells: a promising alternative for power generation and waste treatment

International Nuclear Information System (INIS)

Vazquez-Larios, A. L.; Solorza-Feria, O.; Rinderknecht-Seijas, N.; Poggi-Varaldo, H. M.

2009-01-01

The current energy crisis has launched a renewed interest on alternative energy sources and non-fossil fuels. One promising technology is the direct production of electricity from organic matter or wastes in microbial fuel cells (MFC). A MFC can be envisioned as an bio-electrochemical reactor that converts the chemical energy stored in chemical bonds into electrical energy via the catalytic activity of microorganisms under anoxic conditions. (Author)

The sequestration of CO2

International Nuclear Information System (INIS)

Le Thiez, P.

2004-01-01

The reduction of greenhouse gas emissions, especially CO 2 , represents a major technological and societal challenge in the fight against climate change. Among the measures likely to reduce anthropic CO 2 emissions, capture and geological storage holds out promise for the future. (author)

Light Management in Flexible OLEDs

NARCIS (Netherlands)

Harkema, S.; Pendyala, R.K.; Geurts, C.G.C.; Helgers, P.L.J.; Levell, J.W.; Wilson, J.S.; MacKerron, D.

2014-01-01

Organic light-emitting diodes (OLEDs) are a promising lighting technology. In particular OLEDs fabricated on plastic foils are believed to hold the future. These planar devices are subject to various optical losses, which requires sophisticated light management solutions. Flexible OLEDs on plastic

Online Programs as Tools to Improve Parenting: A meta-analytic review

NARCIS (Netherlands)

Prof. Dr. Jo J.M.A Hermanns; Prof. Dr. Ruben R.G. Fukkink; dr. Christa C.C. Nieuwboer

2013-01-01

Background. A number of parenting programs, aimed at improving parenting competencies,have recently been adapted or designed with the use of online technologies. Although webbased services have been claimed to hold promise for parent support, a meta-analytic review of online parenting interventions

Online programs as tools to improve parenting: A meta-analytic review

NARCIS (Netherlands)

Nieuwboer, C.C.; Fukkink, R.G.; Hermanns, J.M.A.

2013-01-01

Background: A number of parenting programs, aimed at improving parenting competencies, have recently been adapted or designed with the use of online technologies. Although web-based services have been claimed to hold promise for parent support, a meta-analytic review of online parenting

problems in spinning in kolfe house-hold utencil factory abstract ...

African Journals Online (AJOL)

Kolfe House-Hold Utensil Factory in Addis Ababa, is producing different types of utensils for house-hold use from commercial aluminium. Deep drawing or/and spinning are the methods used for shaping this metal to desired shape and size, though some small parts are cast too. One of their products is kettle, which is.

The Promise of Education Information Systems: How Technology Can Improve School Management and Success

Science.gov (United States)

Levenson, Nathan; Boser, Ulrich

2014-01-01

Many school district strategic plans and education conferences are aggressively embracing technology to improve teaching and learning. Classroom technology typically includes blended learning, personalized learning, online courses for students, and professional development for teachers, among many other things. As districts wrestle with tighter…

Empowerment Amongst Teachers Holding Leadership Positions

Science.gov (United States)

Avidov-Ungar, Orit; Friedman, Izhak; Olshtain, Elite

2014-01-01

This study used semi-structured in-depth interviews to explore empowerment patterns among teachers who hold leadership positions in school. Our qualitative analysis presents a hierarchical ladder with three types of empowerment amongst these teachers, ranging from limited empowerment through rewarding empowerment to change-enhancing empowerment.…

12 CFR 1732.7 - Record hold.

Science.gov (United States)

2010-01-01

... Banking OFFICE OF FEDERAL HOUSING ENTERPRISE OVERSIGHT, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SAFETY AND SOUNDNESS RECORD RETENTION Record Retention Program § 1732.7 Record hold. (a) Definition. For... Enterprise or OFHEO that the Enterprise is to retain records relating to a particular issue in connection...

DICOM standard in computer-aided medical technologies

International Nuclear Information System (INIS)

Plotnikov, A.V.; Prilutskij, D.A.; Selishchev, S.V.

1997-01-01

The paper outlines one of the promising standards to transmit images in medicine, in radiology in particular. the essence of the standard DICOM is disclosed and promises of its introduction into computer-aided medical technologies

Harness the Power of Technology

Science.gov (United States)

Duncan, Arne

2011-01-01

Today, U.S. educators are teaching in the midst of a technological revolution. Technology promises to provide innovative solutions in the nation's classrooms, just as it has transformed the way people communicate, socialize, and conduct business. In this article, the author argues that now is the time to harness technology to revolutionize the way…

A Real-Time Holding Decision Rule Accounting for Passenger Travel Cost

NARCIS (Netherlands)

Laskaris,; Cats, O.; Jenelius, E; Viti, F

2016-01-01

Holding has been extensively investigated as a strategy to mitigate the inherently stochastic nature of public transport operations. Holding focuses on either regulating vehicle headways using a rule-based approach or minimizing passenger travel cost by employing optimization models. This paper

Monte Carlo study of holding forces for tank cars on grades

Science.gov (United States)

2013-04-15

This paper describes a numerical procedure to examine the holding forces needed to secure a cut of railroad tank cars staged on a grade during loading and unloading operations. Holding forces are created by applying emergency brake systems and blocki...

Improving livestock for agriculture - technological progress from random transgenesis to precision genome editing heralds a new era.

Science.gov (United States)

Laible, Götz; Wei, Jingwei; Wagner, Stefan

2015-01-01

Humans have a long history in shaping the genetic makeup of livestock to optimize production and meet growing human demands for food and other animal products. Until recently, this has only been possible through traditional breeding and selection, which is a painstakingly slow process of accumulating incremental gains over a long period. The development of transgenic livestock technology offers a more direct approach with the possibility for making genetic improvements with greater impact and within a single generation. However, initially the technology was hampered by technical difficulties and limitations, which have now largely been overcome by progressive improvements over the past 30 years. Particularly, the advent of genome editing in combination with homologous recombination has added a new level of efficiency and precision that holds much promise for the genetic improvement of livestock using the increasing knowledge of the phenotypic impact of genetic sequence variants. So far not a single line of transgenic livestock has gained approval for commercialization. The step change to genome-edited livestock with precise sequence changes may accelerate the path to market, provided applications of this new technology for agriculture can deliver, in addition to economic incentives for producers, also compelling benefits for animals, consumers, and the environment. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Leveraging technology to enhance addiction treatment and recovery.

Science.gov (United States)

Marsch, Lisa A

2012-01-01

Technology such as the Internet and mobile phones offers considerable promise for affecting the assessment, prevention, and treatment of and recovery from substance use disorders. Technology may enable entirely new models of behavioral health care within and outside of formal systems of care. This article reviews the promise of technology-based therapeutic tools for affecting the quality and reach of addiction treatment and recovery support systems, as well as the empirical support to date for this approach. Potential models for implementing technology-based interventions targeting substance use disorders are described. Opportunities to optimize the effectiveness and impact of technology-based interventions targeting addiction and recovery, along with outstanding research needs, are discussed.

How Important Is a Reproducible Breath Hold for Deep Inspiration Breath Hold Breast Radiation Therapy?

International Nuclear Information System (INIS)

Wiant, David; Wentworth, Stacy; Liu, Han; Sintay, Benjamin

2015-01-01

Purpose: Deep inspiration breath hold (DIBH) for left-sided breast cancer has been shown to reduce heart dose. Surface imaging helps to ensure accurate breast positioning, but it does not guarantee a reproducible breath hold (BH) at DIBH treatments. We examine the effects of variable BH positions for DIBH treatments. Methods and Materials: Twenty-five patients who underwent free breathing (FB) and DIBH scans were reviewed. Four plans were created for each patient: FB, DIBH, FB-DIBH (the DIBH plans were copied to the FB images and recalculated, and image registration was based on breast tissue), and P-DIBH (a partial BH with the heart shifted midway between the FB and DIBH positions). The FB-DIBH plans give a “worst-case” scenario for surface imaging DIBH, where the breast is aligned by surface imaging but the patient is not holding their breath. Kolmogorov-Smirnov tests were used to compare the dose metrics. Results: The DIBH plans gave lower heart dose and comparable breast coverage versus FB in all cases. The FB-DIBH plans showed no significant difference versus FB plans for breast coverage, mean heart dose, or maximum heart dose (P≥.10). The mean heart dose differed between FB-DIBH and FB by <2 Gy for all cases, and the maximum heart dose differed by <2 Gy for 21 cases. The P-DIBH plans showed significantly lower mean heart dose than FB (P<.01). The mean heart doses for the P-DIBH plans were < FB for 22 cases, the maximum dose was < FB for 18 cases. Conclusions: A DIBH plan delivered to a FB patient setup with surface imaging will yield dosimetry similar to that of a plan created and delivered FB. A DIBH plan delivered with even a partial BH can give reduced heart dose compared with FB techniques.

How Important Is a Reproducible Breath Hold for Deep Inspiration Breath Hold Breast Radiation Therapy?

Energy Technology Data Exchange (ETDEWEB)

Wiant, David, E-mail: David.wiant@conehealth.com; Wentworth, Stacy; Liu, Han; Sintay, Benjamin

2015-11-15

Purpose: Deep inspiration breath hold (DIBH) for left-sided breast cancer has been shown to reduce heart dose. Surface imaging helps to ensure accurate breast positioning, but it does not guarantee a reproducible breath hold (BH) at DIBH treatments. We examine the effects of variable BH positions for DIBH treatments. Methods and Materials: Twenty-five patients who underwent free breathing (FB) and DIBH scans were reviewed. Four plans were created for each patient: FB, DIBH, FB-DIBH (the DIBH plans were copied to the FB images and recalculated, and image registration was based on breast tissue), and P-DIBH (a partial BH with the heart shifted midway between the FB and DIBH positions). The FB-DIBH plans give a “worst-case” scenario for surface imaging DIBH, where the breast is aligned by surface imaging but the patient is not holding their breath. Kolmogorov-Smirnov tests were used to compare the dose metrics. Results: The DIBH plans gave lower heart dose and comparable breast coverage versus FB in all cases. The FB-DIBH plans showed no significant difference versus FB plans for breast coverage, mean heart dose, or maximum heart dose (P≥.10). The mean heart dose differed between FB-DIBH and FB by <2 Gy for all cases, and the maximum heart dose differed by <2 Gy for 21 cases. The P-DIBH plans showed significantly lower mean heart dose than FB (P<.01). The mean heart doses for the P-DIBH plans were

Molten core material holding device in a nuclear reactor

International Nuclear Information System (INIS)

Nakamura, Hisashi; Tanaka, Nobuo; Takahashi, Katsuro.

1985-01-01

Purpose: To improve the function of cooling to hold molten core materials in a molten core material holding device. Constitution: Plenum structures are formed into a pan-like configuration, in which liners made of metal having high melting point and relatively high heat conductivity such as tantalum, tungsten, rhenium or alloys thereof are integrally appended to hold and directly cool the molten reactor core materials. Further, a plurality of heat pipes, passing through the plenum structures, facing the cooling portion thereof to the coolants at the outer side and immersing the heating portion into the molten core materials fallen to deposit in the inner liners are disposed radially. Furthermore, heat pipes embodded in the plenum structure are disposed in the same manner below the liners. Thus, the plenum structures and the molten reactor core materials can be cooled at a high efficiency. (Seki, T.)

IMPROVEMENT OF ROAD-HOLDING ABILITY FOR “BELARUS” TRACTORS

Directory of Open Access Journals (Sweden)

V. P. Boikov

2016-01-01

Full Text Available Introduction of new efficient braking systems for energy-packed tractors is of great importance for agricultural production. Foreign tractor manufacturing companies are implementing brake systems and in addition to their main function they fulfil function for holding of the given driving direction. The paper considers achievements in the field of electronic systems for tractor road-holding ability. A diagram on proportion of high-power tractors in total export volume of tractors and machinery manufactured in Belarus in the period of 2007–2010 has been drawn in the paper. The paper also proposes a comparative diagram on tractor speeds of international manufacturers which can serve as indicators of speed and road-holding ability of tractors with special electronic systems and without them. The paper contains an analysis of various braking mechanisms of planetary gears and detailed description of their design. A scheme of a laboratory facility for investigation of planetary gear usage as a breaking mechanism while changing conditions of jamming has been presented in the paper. The paper provides description on graph dependencies of current strength and voltage on as a function of the braking torque which is applied to a planetary gear. Nowadays energy-packed “Belarus”-tractors of Class 5 do not have a separate braking for each of four wheels. Therefore, it is proposed to use planetary gearbox of the rear-axle drive being available in every wheel as the basis of a service brake with the purpose to implement the described design. Using such scheme it is possible to execute an introduction of electronic systems for road-holding ability. A generalized scheme of an electronic system for tractor road-holding ability which can ensure separate breaking of all tractor wheels has been drawn out on the basis of the existing automotive electronic systems.

Factors Affecting Corporate Cash Holding of Non-Financial Firms in Pakistan

Directory of Open Access Journals (Sweden)

Atif Kafayat

2014-06-01

Full Text Available The previous researches explore the question of why firms hold cash. But there are few researches done in developing countries like Pakistan. The need for cash is characterized by its policies of firms regarding capital structure, working capital requirements, cash flow management, dividend payments, and asset management. In this paper, the impact of these factors is normally analyzed under the framework of Tradeoff theory, Pecking Order Theory and Free Cash Flow Theory. This paper focuses on determining the level of corporate cash holdings of non-financial Pakistani firms, and cash holding requirement among different industries. The data is set for period of 2008- 2012 by using the data of 40companies and 6 industries. The findings of the study support the theories. Which show that firm size, net working capital, leverage, Capital Expenditure and Dividend significantly affect the cash holdings of non-financial firms in Pakistan.

Promising designs of compact heat exchangers for modular HTRs using the Brayton cycle

International Nuclear Information System (INIS)

Pra, Franck; Tochon, Patrice; Mauget, Christian; Fokkens, Jan; Willemsen, Sander

2008-01-01

The presented study was carried out within the Work Package 2 'Recuperator' of the High Temperature Reactor-E European program. High Temperature gas cooled Reactor concepts with a direct cycle have become potentially interesting for the future. Theoretically, these concepts provide higher efficiency than a classical steam cycle. Within the Brayton cycle the helium/helium recuperator, required to achieve the high efficiency, has to work under very harsh conditions (temperature, pressure, and pressure difference between circuits). Within the project the most promising technologies for the compact recuperator were investigated. First, the requirements for the recuperator to operate under the direct Brayton cycle have been defined. Based on these requirements the various potential technologies available on the market have been investigated. Two particular technologies (HEATRIC Printed Circuit Heat Exchanger, NORDON plate fin concept) have been selected as most promising. For the former, a precise description has been given and a mock-up has been fabricated and tested in the Claire loop at CEA. In the Claire loop the Printed Circuit Heat Exchanger mock-up has been subjected to thermal shocks, which are considered to be representative for a recuperator. Prior to the experimental testing coupled Computational Fluid Dynamic (CFD) and Finite Element analyses have been performed to give insight into the thermal and mechanical behaviour of the mock-ups during the thermal shock. Based on these results the experimental measuring program has been optimized. Upon completion of the tests the experimental and numerical results have been compared. Based on the results from the investigation performed recommendations are given for the full-size recuperator using the selected technologies

Towards Developing an Industry-Validated Food Technology Curriculum in Afghanistan

Science.gov (United States)

Ebner, Paul; McNamara, Kevin; Deering, Amanda; Oliver, Haley; Rahimi, Mirwais; Faisal, Hamid

2017-01-01

Afghanistan remains an agrarian country with most analyses holding food production and processing as key to recovery. To date, however, there are no public or private higher education departments focused on food technology. To bridge this gap, Herat University initiated a new academic department conferring BS degrees in food technology. Models for…

The Determinants of Corporate Cash Holdings- An Empirical study from UK Firms

OpenAIRE

GUO, YI

2013-01-01

Cash holding is most important financial decision in the company management strategy. In this dissertation, the determinants of corporate cash holdings in UK non-financial publicly traded firms over the period from 2003 to 2012 are investigated. Our study finds that growth opportunities and cash flow and cash flow variability are positively associated with the level of corporate cash holdings, while firm size, leverage, net working capital, bank debt and dividend payment have negative impact ...

12 CFR 575.10 - Acquisition and disposition of savings associations, savings and loan holding companies, and...

Science.gov (United States)

2010-01-01

... associations, savings and loan holding companies, and other corporations by mutual holding companies. 575.10... COMPANIES § 575.10 Acquisition and disposition of savings associations, savings and loan holding companies... savings and loan holding company in the stock form that is not a subsidiary holding company, provided the...

Internationalization and Corporate Cash Holdings: Evidence from Brazil and Mexico

Directory of Open Access Journals (Sweden)

Newton Arata

2015-05-01

Full Text Available This research expands on previous studies of cash holdings and their determinants by studying the relationship between the degree of internationalization and the level of corporate cash holdings. We used a sample of nonfinancial, publicly traded companies from Brazil and Mexico for the period from 2006 to 2010. Our results suggest that the degree of internationalization is a determinant of cash, and that cash holding increases quadratically as the degree of company internationalization grows. Such behavior was different from the North American company studies in Chiang and Wang (2011. Similar to previous studies, both Trade-off and Pecking Order predictions are relevant control variables in our model. Finally, companies held less cash on their balance sheets during the precrisis period.

"Resuscitation" of marginal liver allografts for transplantation with machine perfusion technology.

Science.gov (United States)

Graham, Jay A; Guarrera, James V

2014-08-01

As the rate of medically suitable donors remains relatively static worldwide, clinicians have looked to novel methods to meet the ever-growing demand of the liver transplant waiting lists worldwide. Accordingly, the transplant community has explored many strategies to offset this deficit. Advances in technology that target the ex vivo "preservation" period may help increase the donor pool by augmenting the utilization and improving the outcomes of marginal livers. Novel ex vivo techniques such as hypothermic, normothermic, and subnormothermic machine perfusion may be useful to "resuscitate" marginal organs by reducing ischemia/reperfusion injury. Moreover, other preservation techniques such as oxygen persufflation are explored as they may also have a role in improving function of "marginal" liver allografts. Currently, marginal livers are frequently discarded or can relegate the patient to early allograft dysfunction and primary non-function. Bench to bedside advances are rapidly emerging and hold promise for expanding liver transplantation access and improving outcomes. Copyright © 2014 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

A case study of a microsystems MSc curriculum

NARCIS (Netherlands)

Mouthaan, A.J.

2004-01-01

This paper tries to define the contents of master's programmes in Nanotechnology or Nanoengineering. This emerging technology holds large promises for industrial innovation and we need to prepare graduates properly as they will be confronted for most of their future careers with these new

Consider Clicking In: Using Audience Response Systems to Spark Discussion

Science.gov (United States)

Barbour, Joshua B.

2013-01-01

Audience response systems, also known as clickers, hold much promise for use in the communication classroom. Yet potential benefits notwithstanding, implementing new technology in the classroom also offers challenges for faculty who must master it themselves while managing students' learning. Successful clicker implementation, like the…

Unlocking the full potential of Open Innovation in the Life Sciences through a classification system

DEFF Research Database (Denmark)

Nilsson, Niclas; Minssen, Timo

2018-01-01

Open Innovation (OI) holds much promise as a new business model for collaborative value creation in life science. From a corporate perspective, benefits include faster access to new relevant technology; the opportunity for Biotechs and Small to Medium-sized Enterprises (SMEs) to explore new marke...

Sadhana | Indian Academy of Sciences

Indian Academy of Sciences (India)

Access to timely and even real-time information to a wide variety of channel and ... sales personnel, line managers, store managers etc. is the key to achieving this. Web services technology holds out a lot of promise for the retail industry in this ...

The sequestration of CO{sub 2}

Energy Technology Data Exchange (ETDEWEB)

Le Thiez, P

2004-07-01

The reduction of greenhouse gas emissions, especially CO{sub 2}, represents a major technological and societal challenge in the fight against climate change. Among the measures likely to reduce anthropic CO{sub 2} emissions, capture and geological storage holds out promise for the future. (author)

Transcriptional landscape estimation from tiling array data using a model of signal shift and drift

DEFF Research Database (Denmark)

Rasmussen, Simon; Jarmer, Hanne Østergaard; Nicolas, P

2009-01-01

MOTIVATION: High-density oligonucleotide tiling array technology holds the promise of a better description of the complexity and the dynamics of transcriptional landscapes. In organisms such as bacteria and yeasts, transcription can be measured on a genome-wide scale with a resolution >25 bp...

Expert paper for the Future Panel on Public Health Genomics

NARCIS (Netherlands)

Stemerding, D.; Krom, A.

2013-01-01

Developments in public health genomics (PHG) hold the promise to be beneficial for individuals and to promote public health. Central to this paper is the idea that given the range of uncertainties and ambiguities related to genome-based information and technologies (GBIT), the responsible

Reliable quantification of BOLD fMRI cerebrovascular reactivity despite poor breath-hold performance.

Science.gov (United States)

Bright, Molly G; Murphy, Kevin

2013-12-01

Cerebrovascular reactivity (CVR) can be mapped using BOLD fMRI to provide a clinical insight into vascular health that can be used to diagnose cerebrovascular disease. Breath-holds are a readily accessible method for producing the required arterial CO2 increases but their implementation into clinical studies is limited by concerns that patients will demonstrate highly variable performance of breath-hold challenges. This study assesses the repeatability of CVR measurements despite poor task performance, to determine if and how robust results could be achieved with breath-holds in patients. Twelve healthy volunteers were scanned at 3 T. Six functional scans were acquired, each consisting of 6 breath-hold challenges (10, 15, or 20 s duration) interleaved with periods of paced breathing. These scans simulated the varying breath-hold consistency and ability levels that may occur in patient data. Uniform ramps, time-scaled ramps, and end-tidal CO2 data were used as regressors in a general linear model in order to measure CVR at the grey matter, regional, and voxelwise level. The intraclass correlation coefficient (ICC) quantified the repeatability of the CVR measurement for each breath-hold regressor type and scale of interest across the variable task performances. The ramp regressors did not fully account for variability in breath-hold performance and did not achieve acceptable repeatability (ICC0.4). Further analysis of intra-subject CVR variability across the brain (ICCspatial and voxelwise correlation) supported the use of end-tidal CO2 data to extract robust whole-brain CVR maps, despite variability in breath-hold performance. We conclude that the incorporation of end-tidal CO2 monitoring into scanning enables robust, repeatable measurement of CVR that makes breath-hold challenges suitable for routine clinical practice. © 2013.

Anatomic and Pathologic Variability During Radiotherapy for a Hybrid Active Breath-Hold Gating Technique

International Nuclear Information System (INIS)

Glide-Hurst, Carri K.; Gopan, Ellen; Hugo, Geoffrey D.

2010-01-01

Purpose: To evaluate intra- and interfraction variability of tumor and lung volume and position using a hybrid active breath-hold gating technique. Methods and Materials: A total of 159 repeat normal inspiration active breath-hold CTs were acquired weekly during radiotherapy for 9 lung cancer patients (12-21 scans per patient). A physician delineated the gross tumor volume (GTV), lungs, and spinal cord on the first breath-hold CT, and contours were propagated semiautomatically. Intra- and interfraction variability of tumor and lung position and volume were evaluated. Tumor centroid and border variability were quantified. Results: On average, intrafraction variability of lung and GTV centroid position was 0.1). Increases in free-breathing tidal volume were associated with increases in breath-hold ipsilateral lung volume (p < 0.05). Conclusions: The breath-hold technique was reproducible within 2 mm during each fraction. Interfraction variability of GTV position and shape was substantial because of tumor volume and breath-hold lung volume change during therapy. These results support the feasibility of a hybrid breath-hold gating technique and suggest that online image guidance would be beneficial.

26 CFR 53.4943-5 - Present holdings acquired by trust or a will.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 17 2010-04-01 2010-04-01 false Present holdings acquired by trust or a will... Business Holdings § 53.4943-5 Present holdings acquired by trust or a will. (a) Interests to which section... terms of a will executed on or before May 26, 1969. (3) Certain revocable trusts. If an interest in a...

Breath-hold duration in man and the diving response induced by face immersion.

Science.gov (United States)

Sterba, J A; Lundgren, C E

1988-09-01

The objective of this study in 5 selected volunteer subjects was to see whether the circulatory diving response which is elicited by breath holding and by cold water on the face would affect the duration of maximal-effort breath holds. Compared to control measurements (breath holding during resting, breathing with 35 degrees C water on the face) breath holding with the face cooled by 20 degrees C water caused a 12% reduction of heart rate, 6% reduction of cardiac output, 33% reduction in [corrected] forearm blood flow, and 9% rise in mean arterial blood pressure, but there was no difference in breath-hold duration (control and experimental both 94 s). There were also no differences in time of appearance of the first involuntary respiratory efforts during breath holding, in alveolar gas exchange, or in breaking-point alveolar O2 and CO2 tensions. When the diving response was magnified by a brief bout of exercise so that there was a 19% [corrected] reduction in heart rate, 23% reduction in cardiac output, and 48% reduction in forearm blood flow, breath-hold duration was still unaffected by face cooling. Compared to intermittent immersions, continuous exposure of the face to cold water abolished the diving response, probably by a cold adaptation of facial thermal receptors. These results with cooling of the face only are consistent with our earlier finding that there was a negative correlation between the duration of a maximal-effort breath hold and the diving response during whole-body submersion in cold water.

Heterogeneity among methicillin-resistant Staphylococcus aureus from Italian pig finishing holdings

DEFF Research Database (Denmark)

Battisti, A.; Franco, A.; Merialdi, G.

2010-01-01

A survey for methicillin-resistant Staphylococcus aureus (MRSA) in finishing pig holdings was carried out in Italy in 2008. MRSA isolates were characterised by spa-. SCCmec- and antimicrobial susceptibility typing. A prevalence of 38% (45/118, 95% CI 29.4-46.9%) positive holdings was observed...

Living Technology

DEFF Research Database (Denmark)

2010-01-01

This book is aimed at anyone who is interested in learning more about living technology, whether coming from business, the government, policy centers, academia, or anywhere else. Its purpose is to help people to learn what living technology is, what it might develop into, and how it might impact...... our lives. The phrase 'living technology' was coined to refer to technology that is alive as well as technology that is useful because it shares the fundamental properties of living systems. In particular, the invention of this phrase was called for to describe the trend of our technology becoming...... increasingly life-like or literally alive. Still, the phrase has different interpretations depending on how one views what life is. This book presents nineteen perspectives on living technology. Taken together, the interviews convey the collective wisdom on living technology's power and promise, as well as its...

Do elite breath-hold divers suffer from mild short-term memory impairments?

Science.gov (United States)

Billaut, François; Gueit, Patrice; Faure, Sylvane; Costalat, Guillaume; Lemaître, Frédéric

2018-03-01

Repeated apneas are associated with severe hypoxemia that may ultimately lead to loss of consciousness in some breath-hold divers. Despite increasing number of practitioners, the relationship between apnea-induced hypoxia and neurocognitive functions is still poorly understood in the sport of free diving. To shed light onto this phenomenon, we examined the impact of long-term breath-hold diving training on attentional processing, short-term memory, and long-term mnesic and executive functions. Thirty-six men matched for age, height, and weight were separated into the following 3 groups: (i) 12 elite breath-hold divers (EBHD), mean static apnea best time 371 s, 105 months mean apnea experience; (ii) 12 novice breath-hold divers, mean best time 243 s, 8.75 months mean apnea experience; and (iii) 12 physical education students with no breath-hold diving experience; all of these participants performed varied written and computerized neuropsychological tasks. Compared with the 2 other groups, the EBHD group was slower to complete the interference card during a Stroop test (F [1,33] = 4.70, p short-term memory impairments.

Pengaruh krisis keuangan global dan karakteristik perusahaan terhadap cash holding perusahaan di Indonesia

Directory of Open Access Journals (Sweden)

Bambang Sutrisno

2016-12-01

Full Text Available The aim of this study is to examine the effect of the global financial crisis and firm characteristics on corporate cash holdings in Indonesia. A total of 101 manufacturing firms listed in the Indonesia Stock Exchange from 2005 to 2014 are examined. This study employs panel regression with fixed effect model. The results show that Indonesia firms hold more cash during the global financial crisis than in the normal times. Investment opportunities set and divident payment have positive effect on cash holding, meanwhile firm size, capital expenditure, liquid assets substitutes, and leverage have negative effect on cash holding. 

Can we still beat "buy-and-hold" for individual stocks?

Science.gov (United States)

Hui, Eddie C. M.; Kevin Chan, Ka Kwan

2014-09-01

Many investors seek for a trading strategy to beat the "buy-and-hold" strategy. In light of this, Hui and Yam (2014) and Hui et al. (2014) derived a trading strategy from the Shiryaev-Zhou index, and found that the resulting strategy outperformed the "buy-and-hold" strategy for western and Asian securitized real estate indices respectively. However, whether the trading strategy works on individual stocks or not is still unknown. This is the first study to test whether the trading strategy can beat the "buy-and-hold" strategy on individual stocks. We construct two trading strategies and compare the resulting profits with the profits arising from the "buy-and-hold" strategy on Hang Seng Index (HSI), Hang Seng Property (HSP) Index and 12 constituent stocks of HSI during the period December 29, 1995-December 31, 2013. The second strategy (Strategy 2) is a new strategy which incorporates short-selling, and has the effect of multiplying the profit. The results show that our trading strategies are less effective on individual stocks than on stock indices, and are more effective on property stocks than on non-property stocks. Moreover, our strategies outperform "buy-and-hold" by a larger extent on stocks of which the Shiryaev-Zhou indices fluctuate less frequently. Furthermore, by tracking the resulting profits of the three strategies at different times along the whole period of observation, our strategies work better during "bad times" than during "good times". This reflects that our trading strategies are especially useful in protecting investors from substantial loss during market downturns.

29 CFR 452.40 - Prior office holding.

Science.gov (United States)

2010-07-01

... DISCLOSURE ACT OF 1959 Candidacy for Office; Reasonable Qualifications § 452.40 Prior office holding. A.... 26 26 Wirtz v. Hotel, Motel and Club Employees Union, Local 6, 391 U.S. 492 at 504. The Court stated...

Kidney motion during free breathing and breath hold for MR-guided radiotherapy

International Nuclear Information System (INIS)

Stam, Mette K; Van Vulpen, Marco; Intven, Martijn; Crijns, Sjoerd P M; Lagendijk, Jan J W; Raaymakers, Bas W; Barendrecht, Maurits M; Zonnenberg, Bernard A

2013-01-01

Current treatments for renal cell carcinoma have a high complication rate due to the invasiveness of the treatment. With the MRI-linac it may be possible to treat renal tumours non-invasively with high-precision radiotherapy. This is expected to reduce complications. To deliver a static dose distribution, radiation gating will be used. In this study the reproducibility and efficiency of free breathing gating and a breath hold treatment of the kidney was investigated. For 15 patients with a renal lesion the kidney motion during 2 min of free breathing and 10 consecutive expiration breath holds was studied with 2D cine MRI. The variability in kidney expiration position and treatment efficiency for gating windows of 1 to 20 mm was measured for both breathing patterns. Additionally the time trend in free breathing and the variation in expiration breath hold kidney position with baseline shift correction was determined. In 80% of the patients the variation in expiration position during free breathing is smaller than 2 mm. No clinically relevant time trends were detected. The variation in expiration breath hold is for all patients larger than the free breathing expiration variation. Gating on free breathing is, for gating windows of 1 to 5 mm more efficient than breath hold without baseline correction. When applying a baseline correction to the breath hold it increases the treatment efficiency. The kidney position is more reproducible in expiration free breathing than non-guided expiration breath hold. For small gating windows it is also more time efficient. Since free breathing also seems more comfortable for the patients it is the preferred breathing pattern for MRI-Linac treatments of the kidney. (paper)

Assistive technologies to overcome sarcopenia in ageing.

Science.gov (United States)

Scott, Rachel A; Callisaya, Michele L; Duque, Gustavo; Ebeling, Peter R; Scott, David

2018-06-01

Sarcopenia is an age-related decline in skeletal muscle mass and function that results in disability and loss of independence. It affects up to 30% of older adults. Exercise (particularly progressive resistance training) and nutrition are key strategies in preventing and reversing declines in muscle mass, strength and power during ageing, but many sarcopenic older adults fail to meet recommended levels of both physical activity and dietary nutrient intake. Assistive technology (AT) describes devices or systems used to maintain or improve physical functioning. These may help sarcopenic older adults to maintain independence, and also to achieve adequate physical activity and nutrition. There is a paucity of research exploring the use of AT in sarcopenic patients, but there is evidence that AT, including walking aids, may reduce functional decline in other populations with disability. Newer technologies, such as interactive and virtual reality games, as well as wearable devices and smartphone applications, smart homes, 3D printed foods, exoskeletons and robotics, and neuromuscular electrical stimulation also hold promise for improving engagement in physical activity and nutrition behaviours to prevent further functional declines. While AT may be beneficial for sarcopenic patients, clinicians should be aware of its potential limitations. In particular, there are high rates of patient abandonment of AT, which may be minimised by appropriate training and monitoring of use. Clinicians should preferentially prescribe AT devices which promote physical activity. Further research is required in sarcopenic populations to identify strategies for effective use of current and emerging AT devices. Copyright © 2018 Elsevier B.V. All rights reserved.

Mastering JavaScript promises

CERN Document Server

Hussain, Muzzamil

2015-01-01

This book is for all the software and web engineers wanting to apply the promises paradigm to their next project and get the best outcome from it. This book also acts as a reference for the engineers who are already using promises in their projects and want to improve their current knowledge to reach the next level. To get the most benefit from this book, you should know basic programming concepts, have a familiarity with JavaScript, and a good understanding of HTML.

Technology innovation for infectious diseases in the developing world.

Science.gov (United States)

So, Anthony D; Ruiz-Esparza, Quentin

2012-10-25

Enabling innovation and access to health technologies remains a key strategy in combating infectious diseases in low- and middle-income countries (LMICs). However, a gulf between paying markets and the endemicity of such diseases has contributed to the dearth of R&D in meeting these public health needs. While the pharmaceutical industry views emerging economies as potential new markets, most of the world's poorest bottom billion now reside in middle-income countries--a fact that has complicated tiered access arrangements. However, product development partnerships--particularly those involving academic institutions and small firms--find commercial opportunities in pursuing even neglected diseases; and a growing pharmaceutical sector in BRICS countries offers hope for an indigenous base of innovation. Such innovation will be shaped by 1) access to building blocks of knowledge; 2) strategic use of intellectual property and innovative financing to meet public health goals; 3) collaborative norms of open innovation; and 4) alternative business models, some with a double bottom line. Facing such resource constraints, LMICs are poised to develop a new, more resource-effective model of innovation that holds exciting promise in meeting the needs of global health.

SEQUENCING BATCH REACTOR: A PROMISING TECHNOLOGY IN WASTEWATER TREATMENT

Directory of Open Access Journals (Sweden)

A. H. Mahvi

2008-04-01

Full Text Available Discharge of domestic and industrial wastewater to surface or groundwater is very dangerous to the environment. Therefore treatment of any kind of wastewater to produce effluent with good quality is necessary. In this regard choosing an effective treatment system is important. Sequencing batch reactor is a modification of activated sludge process which has been successfully used to treat municipal and industrial wastewater. The process could be applied for nutrients removal, high biochemical oxygen demand containing industrial wastewater, wastewater containing toxic materials such as cyanide, copper, chromium, lead and nickel, food industries effluents, landfill leachates and tannery wastewater. Of the process advantages are single-tank configuration, small foot print, easily expandable, simple operation and low capital costs. Many researches have been conducted on this treatment technology. The authors had been conducted some investigations on a modification of sequencing batch reactor. Their studies resulted in very high percentage removal of biochemical oxygen demand, chemical oxygen demand, total kjeldahl nitrogen, total nitrogen, total phosphorus and total suspended solids respectively. This paper reviews some of the published works in addition to experiences of the authors.

Overview of existing cartilage repair technology.

Science.gov (United States)

McNickle, Allison G; Provencher, Matthew T; Cole, Brian J

2008-12-01

Currently, autologous chondrocyte implantation and osteochondral grafting bridge the gap between palliation of cartilage injury and resurfacing via arthroplasty. Emerging technologies seek to advance first generation techniques and accomplish several goals including predictable outcomes, cost-effective technology, single-stage procedures, and creation of durable repair tissue. The biologic pipeline represents a variety of technologies including synthetics, scaffolds, cell therapy, and cell-infused matrices. Synthetic constructs, an alternative to biologic repair, resurface a focal chondral defect rather than the entire joint surface. Scaffolds are cell-free constructs designed as a biologic "net" to augment marrow stimulation techniques. Minced cartilage technology uses stabilized autologous or allogeneic fragments in 1-stage transplantation. Second and third generation cell-based methods include alternative membranes, chondrocyte seeding, and culturing onto scaffolds. Despite the promising early results of these products, significant technical obstacles remain along with unknown long-term durability. The vast array of developing technologies has exceptional promise and the potential to revolutionize the cartilage treatment algorithm within the next decade.

"Send & Hold" Clinical Decision Support Rules improvement to reduce unnecessary testing of vitamins A, E, K, B1, B2, B3, B6 and C.

Science.gov (United States)

Rodriguez-Borja, Enrique; Corchon-Peyrallo, Africa; Barba-Serrano, Esther; Villalba Martínez, Celia; Carratala Calvo, Arturo

2018-02-03

We assessed the impact of several "send & hold" clinical decision support rules (CDSRs) within the electronical request system for vitamins A, E, K, B1, B2, B3, B6 and C for all outpatients at a large health department. When ordered through electronical request, providers (except for all our primary care physicians who worked as a non-intervention control group) were always asked to answer several compulsory questions regarding main indication, symptomatology, suspected diagnosis, vitamin active treatments, etc., for each vitamin test using a drop-down list format. After samples arrival, tests were later put on hold internally by our laboratory information system (LIS) until review for their appropriateness was made by two staff pathologists according to the provided answers and LIS records (i.e. "send & hold"). The number of tests for each analyte was compared between the 10-month period before and after CDSRs implementation in both groups. After implementation, vitamins test volumes decreased by 40% for vitamin A, 29% for vitamin E, 42% for vitamin K, 37% for vitamin B1, 85% for vitamin B2, 68% for vitamin B3, 65% for vitamin B6 and 59% for vitamin C (all p values 0.03 or lower except for vitamin B3), whereas in control group, the majority increased or remained stable. In patients with rejected vitamins, no new requests and/or adverse clinical outcome comments due to this fact were identified. "Send & hold" CDSRs are a promising informatics tool that can support in utilization management and enhance the pathologist's leadership role as tests specialist.

Can Robotic Interaction Improve Joint Attention Skills?

Science.gov (United States)

Warren, Zachary E.; Zheng, Zhi; Swanson, Amy R.; Bekele, Esubalew; Zhang, Lian; Crittendon, Julie A.; Weitlauf, Amy F.; Sarkar, Nilanjan

2015-01-01

Although it has often been argued that clinical applications of advanced technology may hold promise for addressing impairments associated with autism spectrum disorder (ASD), relatively few investigations have indexed the impact of intervention and feedback approaches. This pilot study investigated the application of a novel robotic interaction…

Consumer attitudes towards nanotechnology in food products

NARCIS (Netherlands)

Steenis, Nigel D.; Fischer, Arnout R.H.

2016-01-01

Purpose – Nanotechnology is a technology that holds much promise for food production. It is, however not clear to what extent consumers will accept different types of nanotechnologies in food products. The purpose of this paper is to research consumer attitudes towards differing applications of

WiMAX technology and network evolution

CERN Document Server

Etemad, Kamran

2010-01-01

WiMAX, the Worldwide Interoperability for Microwave Access, represents a paradigm shift in telecommunications technology. It offers the promise of cheaper, smaller, and simpler technology compared to existing broadband options such as DSL, cable, fiber, and 3G wireless.

Benevolent technotopias and hitherto unimaginable meats: Tracing the promises of in vitro meat

OpenAIRE

Jönsson, Erik

2016-01-01

Today, in vitro (Latin: in glass) meat researchers strive to overhaul meat production technologies by producing meat outside animal bodies, primarily by culturing cells. In the process, meat should become healthier, more environmentally friendly and kinder to animals. In this article, I scrutinize (and problematize) this promissory discourse by examining the world that proponents envision alongside the world from which promises emerge. First, I trace the increasing number of publications stri...

CASH HOLDING, GOOD CORPORATE GOVERNANCE AND FIRM VALUE

Directory of Open Access Journals (Sweden)

Prana Wahyu Nisasmara

2016-12-01

Full Text Available This research aims to understand the influence of profitability, capital structure, cash holding, and GCG (Good Corporate Governance on firm value.  The samples of this study were the property sector and real estate companies listed on Indonesia Stock Exchange (IDX in the period of 2008-2013. The data used from the annual report company. The methods of data analysis were multiple regression models and analyzed using IBM SPSS software. The results of this study are profitability has no influence on firm value, capital structure has positive influence on firm value, cash holding has no influence on firm value and GCG a has a positive influence on firm value.

Package Holds Five Monolithic Microwave Integrated Circuits

Science.gov (United States)

Mysoor, Narayan R.; Decker, D. Richard; Olson, Hilding M.

1996-01-01

Packages protect and hold monolithic microwave integrated circuit (MMIC) chips while providing dc and radio-frequency (RF) electrical connections for chips undergoing development. Required to be compact, lightweight, and rugged. Designed to minimize undesired resonances, reflections, losses, and impedance mismatches.

12 CFR 1500.3 - What are the holding periods permitted for merchant banking investments?

Science.gov (United States)

2010-01-01

... includes a depository institution controlled by the financial holding company and any subsidiary of such a depository institution. (4) Approval required to hold interests held in excess of time limit. A financial... financial holding company; (iii) Market conditions; (iv) The nature of the portfolio company's business; (v...

Step voltage with periodic hold-up etching: A novel porous silicon formation

International Nuclear Information System (INIS)

Naddaf, M.; Awad, F.; Soukeih, M.

2007-01-01

A novel etching method for preparing light-emitting porous silicon (PS) is developed. A gradient steps (staircase) voltage is applied and hold-up for different periods of time between p-type silicon wafers and a graphite electrode in HF based solutions periodically. The single applied staircase voltage (0-30 V) is ramped in equal steps of 0.5 V for 6 s, and hold at 30 V for 30 s at a current of 6 mA. The current during hold-up time (0 V) was less than 10 μA. The room temperature photoluminescence (PL) behavior of the PS samples as a function of etching parameters has been investigated. The intensity of PL peak is initially increased and blue shifted on increasing etching time, but decreased after prolonged time. These are correlated with the study of changes in surface morphology using atomic force microscope (AFM), porosity and electrical conductance measurements. The time of holding-up the applied voltage during the formation process is found to highly affect the PS properties. On increasing the holding-up time, the intensity of PL peak is increased and blue shifted. The contribution of holding-up the applied steps during the formation process of PS is seen to be more or less similar to the post chemical etching process. It is demonstrated that this method can yield a porous silicon layer with stronger photoluminescence intensity and blue shifted than the porous silicon layer prepared by DC etching

Step voltage with periodic hold-up etching: A novel porous silicon formation

Energy Technology Data Exchange (ETDEWEB)

Naddaf, M. [Department of Physics, Atomic Energy Commission of Syria (AECS), Damascus P.O. Box 6091 (Syrian Arab Republic)]. E-mail: scientific@aec.org.sy; Awad, F. [Department of Physics, Atomic Energy Commission of Syria (AECS), Damascus P.O. Box 6091 (Syrian Arab Republic); Soukeih, M. [Department of Physics, Atomic Energy Commission of Syria (AECS), Damascus P.O. Box 6091 (Syrian Arab Republic)

2007-05-16

A novel etching method for preparing light-emitting porous silicon (PS) is developed. A gradient steps (staircase) voltage is applied and hold-up for different periods of time between p-type silicon wafers and a graphite electrode in HF based solutions periodically. The single applied staircase voltage (0-30 V) is ramped in equal steps of 0.5 V for 6 s, and hold at 30 V for 30 s at a current of 6 mA. The current during hold-up time (0 V) was less than 10 {mu}A. The room temperature photoluminescence (PL) behavior of the PS samples as a function of etching parameters has been investigated. The intensity of PL peak is initially increased and blue shifted on increasing etching time, but decreased after prolonged time. These are correlated with the study of changes in surface morphology using atomic force microscope (AFM), porosity and electrical conductance measurements. The time of holding-up the applied voltage during the formation process is found to highly affect the PS properties. On increasing the holding-up time, the intensity of PL peak is increased and blue shifted. The contribution of holding-up the applied steps during the formation process of PS is seen to be more or less similar to the post chemical etching process. It is demonstrated that this method can yield a porous silicon layer with stronger photoluminescence intensity and blue shifted than the porous silicon layer prepared by DC etching.

12 CFR 225.172 - What are the holding periods permitted for merchant banking investments?

Science.gov (United States)

2010-01-01

... institution controlled by the financial holding company and any subsidiary of such a depository institution... company to the company and the risks that disposing of the investment may pose to the financial holding... history of involvement by the financial holding company in the management and operations of the company...

New Technology, Changing Pedagogies? Exploring the Concept of Remote Teaching Placement Supervision

Science.gov (United States)

Chilton, Helen; McCracken, Wendy

2017-01-01

Mobile technologies continue to have a growing influence on contemporary society, are becoming more commonplace within tertiary educational settings and hold the potential to impact on the learning process. This project evaluation considers the perspectives of participants who trialled the use of new technology to enable remote supervision and…

78 FR 26032 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

Science.gov (United States)

2013-05-03

..., North Carolina; Frank B. Holding, Sr., Smithfield, North Carolina; Ella Ann Holding, Smithfield, North..., individually and together with Olivia Britton Holding, Raleigh, North Carolina; Frank B. Holding, Sr... Brown Holding, Jr., Raleigh, North Carolina; Frank B. Holding, Sr., Smithfield, North Carolina; Ella Ann...

Towards the Biological Understanding of CTC: Capture Technologies, Definitions and Potential to Create Metastasis

Directory of Open Access Journals (Sweden)

Ana M.C. Barradas

2013-12-01

Full Text Available Circulating Tumor Cells (CTC are rare cells originated from tumors that travel into the blood stream, extravasate to different organs of which only a small fraction will develop into metastasis. The presence of CTC enumerated with the CellSearch system is associated with a relative short survival and their continued presence after the first cycles of therapy indicates a futile therapy in patients with metastatic carcinomas. Detailed characterization of CTC holds the promise to enable the choice of the optimal therapy for the individual patients during the course of the disease. The phenotype, physical and biological properties are however not well understood making it difficult to assess the merit of recent technological advancements to improve upon the capture of CTC or to evaluate their metastatic potential. Here we will discuss the recent advances in the classification of CTC captured by the CellSearch system, the implications of their features and numbers. Latest capture platforms are reviewed and placed in the light of technology improvements needed to detect CTC. Physical properties, phenotype, viability and proliferative potential and means to assess their proliferation and metastatic capacity will be summarized and placed in the context of the latest CTC capture platforms.

The Economics of an Admissions Holding Unit.

Science.gov (United States)

Schreyer, Kraftin E; Martin, Richard

2017-06-01

With increasing attention to the actual cost of delivering care, return-on-investment calculations take on new significance. Boarded patients in the emergency department (ED) are harmful to clinical care and have significant financial opportunity costs. We hypothesize that investment in an admissions holding unit for admitted ED patients not only captures opportunity cost but also significantly lowers direct cost of care. This was a three-phase study at a busy urban teaching center with significant walkout rate. We first determined the true cost of maintaining a staffed ED bed for one patient-hour and compared it to alternative settings. The opportunity cost for patients leaving without being seen was then conservatively estimated. Lastly, a convenience sample of admitted patients boarding in the ED was observed continuously from one hour after decision-to-admit until physical departure from the ED to capture a record of every interaction with a nurse or physician. Personnel costs per patient bed-hour were $58.20 for the ED, $24.80 for an inpatient floor, $19.20 for the inpatient observation unit, and $10.40 for an admissions holding area. An eight-bed holding unit operating at practical capacity would free 57.4 hours of bed space in the ED and allow treatment of 20 additional patients. This could yield increased revenues of $27,796 per day and capture opportunity cost of $6.09 million over 219 days, in return for extra staffing costs of $218,650. Analysis of resources used for boarded patients was determined by continuous observation of a convenience sample of ED-boarded patients, which found near-zero interactions with both nursing and physicians during the boarding interval. Resource expense per ED bed-hour is more than twice that in non-critical care inpatient units. Despite the high cost of available resources, boarded non-critical patients receive virtually no nursing or physician attention. An admissions holding unit is remarkably effective in avoiding the

The Economics of an Admissions Holding Unit

Directory of Open Access Journals (Sweden)

Kraftin E. Schreyer

2017-05-01

Full Text Available Introduction: With increasing attention to the actual cost of delivering care, return-on-investment calculations take on new significance. Boarded patients in the emergency department (ED are harmful to clinical care and have significant financial opportunity costs. We hypothesize that investment in an admissions holding unit for admitted ED patients not only captures opportunity cost but also significantly lowers direct cost of care. Methods: This was a three-phase study at a busy urban teaching center with significant walkout rate. We first determined the true cost of maintaining a staffed ED bed for one patient-hour and compared it to alternative settings. The opportunity cost for patients leaving without being seen was then conservatively estimated. Lastly, a convenience sample of admitted patients boarding in the ED was observed continuously from one hour after decision-to-admit until physical departure from the ED to capture a record of every interaction with a nurse or physician. Results: Personnel costs per patient bed-hour were $58.20 for the ED, $24.80 for an inpatient floor, $19.20 for the inpatient observation unit, and $10.40 for an admissions holding area. An eight-bed holding unit operating at practical capacity would free 57.4 hours of bed space in the ED and allow treatment of 20 additional patients. This could yield increased revenues of $27,796 per day and capture opportunity cost of $6.09 million over 219 days, in return for extra staffing costs of $218,650. Analysis of resources used for boarded patients was determined by continuous observation of a convenience sample of ED-boarded patients, which found near-zero interactions with both nursing and physicians during the boarding interval. Conclusion: Resource expense per ED bed-hour is more than twice that in non-critical care inpatient units. Despite the high cost of available resources, boarded non-critical patients receive virtually no nursing or physician attention. An

Making Women Count: Gender-Typing, Technology and Path Dependencies in Dutch Statistical Data Processing

NARCIS (Netherlands)

van den Ende, Jan; van Oost, Elizabeth C.J.

2001-01-01

This article is a longitudinal analysis of the relation between gendered labour divisions and new data processing technologies at the Dutch Central Bureau of Statistics (CBS). Following social-constructivist and evolutionary economic approaches, the authors hold that the relation between technology

The ins and outs of breath holding: simple demonstrations of complex respiratory physiology.

Science.gov (United States)

Skow, Rachel J; Day, Trevor A; Fuller, Jonathan E; Bruce, Christina D; Steinback, Craig D

2015-09-01

The physiology of breath holding is complex, and voluntary breath-hold duration is affected by many factors, including practice, psychology, respiratory chemoreflexes, and lung stretch. In this activity, we outline a number of simple laboratory activities or classroom demonstrations that illustrate the complexity of the integrative physiology behind breath-hold duration. These activities require minimal equipment and are easily adapted to small-group demonstrations or a larger-group inquiry format where students can design a protocol and collect and analyze data from their classmates. Specifically, breath-hold duration is measured during a number of maneuvers, including after end expiration, end inspiration, voluntary prior hyperventilation, and inspired hyperoxia. Further activities illustrate the potential contribution of chemoreflexes through rebreathing and repeated rebreathing after a maximum breath hold. The outcome measures resulting from each intervention are easily visualized and plotted and can comprise a comprehensive data set to illustrate and discuss complex and integrated cardiorespiratory physiology. Copyright © 2015 The American Physiological Society.

21 CFR 111.465 - What requirements apply to holding reserve samples of dietary supplements?

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What requirements apply to holding reserve samples... Distributing § 111.465 What requirements apply to holding reserve samples of dietary supplements? (a) You must hold reserve samples of dietary supplements in a manner that protects against contamination and...

Organizational suggestion system in the era of holding by developing an innovative model : the case of bonyade ta avon holding in Iran(an applied model

Directory of Open Access Journals (Sweden)

Meysam Ghasemi

2010-01-01

Full Text Available One of the popular ways of taking advantage of personnel creativity is through suggestionsystems. Our main question is how to implement suggestion system in holding with conglomeratestructure. The paper presents an innovative model that were named ITFSK Model with accordanceof Bonayade Taavone (a holding that has many companies and institutions with conglomeratestructure. ITFSK is a model that explains how participation management and suggestion system isimplemented effectively in huge Enterprises (holding and this approach brings continuousimprovement (kaizen and it impacts the productivity of these enterprises.The paper is based on field research and the research in Bonyade Tavan that has 22 companies and2 institutions that activity fields of the subholdings is very varied.Our model consists of five main parts such as ideas bank, think-tank, feedback, sharing ofknowledge and kaizen that was named ITFSK.Implementation of “Suggestion system” rules has immediate and significant effects on theproductivity of activities in the jobs, thus influencing the performance of processes in the analyzedorganization. Suggestion system can result in kaizen and innovation in environment oforganization.The model was used to implement and evaluate a suggestion system of holding with conglomeratedstructure. The application of the model to evaluate the suggestion system provided some goodinsights and highlighted some areas of improvement.

Report on achievements of research and development of an automatic sewing system in fiscal 1986. Cloth handling technology; 1986 nendo jido hosei system no kenkyu kaihatsu seika hokokusho. Kiji handling gijutsu

Energy Technology Data Exchange (ETDEWEB)

NONE

1987-03-01

The Automatic Sewing System Technology Research Association was commissioned from the Agency of Industrial Science and Technology on the 'development of an automatic sewing system'. The association has performed the research and development by dividing the subject into such component technologies as a total system and sewing preparation and processing technology, a sewing and assembling technology, a cloth handling technology, and a system management and control technology. This paper reports the achievement of the research on the cloth handling technology. This technology may be divided into such component technologies as (1) the cloth holding technology, (2) the high-functional positioning technology, and (3) the soft cloth moving technology. For the technology (1), development was made on the principle models, such as the vertical holding and parallel holding type modules and the cloth operating type module, as well as on the principle model for an auxiliary equipment for holding cloth edges. For the technology (2), development was made on the handler, controller, and coordinated operation control and teaching system. Discussions were given on optimal device configuration, functions required in the devices, and evaluation methods, as the high-functional positioning technology for the sewing process and pressing process. Prototype devices were designed and fabricated. For the technology (3), prototype models of the improved version were fabricated for the stock module and confluence model, their functions and performances were confirmed, and problems and points requiring improvement were extracted for prototype fabrication. (NEDO)

Report on achievements of research and development of an automatic sewing system in fiscal 1986. Cloth handling technology; 1986 nendo jido hosei system no kenkyu kaihatsu seika hokokusho. Kiji handling gijutsu

Energy Technology Data Exchange (ETDEWEB)

NONE

1987-03-01

The Automatic Sewing System Technology Research Association was commissioned from the Agency of Industrial Science and Technology on the 'development of an automatic sewing system'. The association has performed the research and development by dividing the subject into such component technologies as a total system and sewing preparation and processing technology, a sewing and assembling technology, a cloth handling technology, and a system management and control technology. This paper reports the achievement of the research on the cloth handling technology. This technology may be divided into such component technologies as (1) the cloth holding technology, (2) the high-functional positioning technology, and (3) the soft cloth moving technology. For the technology (1), development was made on the principle models, such as the vertical holding and parallel holding type modules and the cloth operating type module, as well as on the principle model for an auxiliary equipment for holding cloth edges. For the technology (2), development was made on the handler, controller, and coordinated operation control and teaching system. Discussions were given on optimal device configuration, functions required in the devices, and evaluation methods, as the high-functional positioning technology for the sewing process and pressing process. Prototype devices were designed and fabricated. For the technology (3), prototype models of the improved version were fabricated for the stock module and confluence model, their functions and performances were confirmed, and problems and points requiring improvement were extracted for prototype fabrication. (NEDO)

Key technologies for expeditions to Mars.

Science.gov (United States)

French, J. R., Jr.

A round-trip manned Mars landing mission, while difficult, is within the realm of today's technology. However, better understood and more practical advanced technologies offer promising improvements in mass performance, and some also enhance certain aspects of self-reliance for manned missions.

A conceptual holding model for veterinary applications

Directory of Open Access Journals (Sweden)

Nicola Ferrè

2014-05-01

Full Text Available Spatial references are required when geographical information systems (GIS are used for the collection, storage and management of data. In the veterinary domain, the spatial component of a holding (of animals is usually defined by coordinates, and no other relevant information needs to be interpreted or used for manipulation of the data in the GIS environment provided. Users trying to integrate or reuse spatial data organised in such a way, frequently face the problem of data incompatibility and inconsistency. The root of the problem lies in differences with respect to syntax as well as variations in the semantic, spatial and temporal representations of the geographic features. To overcome these problems and to facilitate the inter-operability of different GIS, spatial data must be defined according to a “schema” that includes the definition, acquisition, analysis, access, presentation and transfer of such data between different users and systems. We propose an application “schema” of holdings for GIS applications in the veterinary domain according to the European directive framework (directive 2007/2/EC - INSPIRE. The conceptual model put forward has been developed at two specific levels to produce the essential and the abstract model, respectively. The former establishes the conceptual linkage of the system design to the real world, while the latter describes how the system or software works. The result is an application “schema” that formalises and unifies the information-theoretic foundations of how to spatially represent a holding in order to ensure straightforward information-sharing within the veterinary community.

Deriving vehicle-to-grid business models from consumer preferences

NARCIS (Netherlands)

Bohnsack, René; van den Hoed, Robert; Oude Reimer, Hugo

2015-01-01

Combining electric cars with utility services seems to be a natural fit and holds the promise to tackle various mobility as well as electricity challenges at the same time. So far no viable business model for vehicle-to-grid technology has emerged, raising the question which characteristics a

The Accessibility of Learning Content for All Students, Including Students with Disabilities, Must Be Addressed in the Shift to Digital Instructional Materials. SETDA Policy Brief

Science.gov (United States)

Fletcher, Geoff; Levin, Doug; Lipper, Katherine; Leichty, Reg

2014-01-01

This is a time of rapid technological advancement, with innovations in education holding great promise for improving teaching and learning, particularly for students with unique needs. High-quality digital educational materials, tools, and resources offer students relevant, up-to-date, and innovative ways to acquire knowledge and skills. Created…

Are Economists More Likely to Hold Stocks?

DEFF Research Database (Denmark)

Christiansen, Charlotte; Joensen, Eyðfrið Juanna Schrøter; Rangvid, Jesper

A unique data set enables us to test the hypothesis that due to informational advantages economists are more likely to hold stocks than otherwise identical investors. Weconfirm that economists have a significantly higher probability of participating in the stockmarket than investors with any other...

Investasi: Komparasi Strategi Buy and Hold dengan Pendekatan Teknikal

Directory of Open Access Journals (Sweden)

Natica Ardani

2012-01-01

Full Text Available This research aims to analyse effectivity of technical analysis moving average compare to buy and hold strategy on index LQ-45 (as emerging market and S&P500 (as developed market. Using descriptive approach, this research analysed by metastock program with moving average exponential crossovers method. This research data samples use LQ45 and S&P500 from year 2001-2011. The findings of this research indicate that technical analysis more effective when economic situation on crisis (bearish. Whereas buy and hold strategy more effective on good economic condition (bullish. The results consistent for LQ-45 and S&P500.

Evaluation of promising technologies for soil salinity amelioration in Timpaki (Crete): a participatory approach

Science.gov (United States)

Panagea, I. S.; Daliakopoulos, I. N.; Tsanis, I. K.; Schwilch, G.

2016-02-01

Soil salinity management can be complex, expensive, and time demanding, especially in arid and semi-arid regions. Besides taking no action, possible management strategies include amelioration and adaptation measures. Here we apply the World Overview of Conservation Approaches and Technologies (WOCAT) framework for the systematic analysis and evaluation and selection of soil salinisation amelioration technologies in close collaboration with stakeholders. The participatory approach is applied in the RECARE (Preventing and Remediating degradation of soils in Europe through Land Care) project case study of Timpaki, a semi-arid region in south-central Crete (Greece) where the main land use is horticulture in greenhouses irrigated by groundwater. Excessive groundwater abstractions have resulted in a drop of the groundwater level in the coastal part of the aquifer, thus leading to seawater intrusion and in turn to soil salinisation. The documented technologies are evaluated for their impacts on ecosystem services, cost, and input requirements using a participatory approach and field evaluations. Results show that technologies which promote maintaining existing crop types while enhancing productivity and decreasing soil salinity are preferred by the stakeholders. The evaluation concludes that rainwater harvesting is the optimal solution for direct soil salinity mitigation, as it addresses a wider range of ecosystem and human well-being benefits. Nevertheless, this merit is offset by poor financial motivation making agronomic measures more attractive to users.

In-process hold-up as a measure of safeguards significance

International Nuclear Information System (INIS)

Hamlin, A.G.

1983-01-01

This paper examines the use of the in-process hold-up itself, as a measure of safeguards significance. It is argued that for any process plant it is possible to define design limits for in-process hold-up, outside which the plant will not operate, or will operate in a detectably abnormal manner. It follows, therefore, that if the in-process hold-up can be derived at frequent intervals by input/output analysis from the start of the campaign, the only diversion that can be made from it during that campaign is limited to the quantity necessary to move the apparent in-process hold-up from its normal operating condition to the upper limiting condition. It also follows that detection of this diversion is as positive for protracted diversion as for abrupt diversion. If that part of the in-process inventory that is only measurable by input/output analysis has an upper operating limit that differs from its normal operating limit by less than a significant safeguards quantity of the material in question, the IAEA's criteria for both quantity and timeliness can be met by a combination of input/output analysis to determine in-process hold-up during the campaign, together with a material balance over the campaign. The paper examines the possibility of applying this measure to process plants in general, discusses means of minimizing the in-process inventory that must be determined by input/output analysis, and the performance required of the input and output analysis. It concludes that with current precision of measurement and with one input and one output batch per day, each measured, the method would be satisfactory for a campaign lasting nearly a year and involving 6 tonnes of plutonium. The paper examines the considerable advantages in verification that would arise from limiting safeguards analyses to the two points of input and output. (author)

Conference Proceedings: Petro-tech 1998 - petroleum information technology : making IT work for Canada's petroleum industry

International Nuclear Information System (INIS)

1998-01-01

The value of information technology in the petroleum industry was explored at this conference. A total of 18 papers were presented in five sessions. The dominant themes of the five sessions were: (1) information technology, delivering value or simply a utility, (2) information technology, corporate drive or passenger, (3) managing and measuring information technology investments, (4) what does the future hold for information technology, and (5) web technology. tabs., figs

Time discretization of the point kinetic equations using matrix exponential method and First-Order Hold

International Nuclear Information System (INIS)

Park, Yujin; Kazantzis, Nikolaos; Parlos, Alexander G.; Chong, Kil To

2013-01-01

Highlights: • Numerical solution for stiff differential equations using matrix exponential method. • The approximation is based on First Order Hold assumption. • Various input examples applied to the point kinetics equations. • The method shows superior useful and effective activity. - Abstract: A system of nonlinear differential equations is derived to model the dynamics of neutron density and the delayed neutron precursors within a point kinetics equation modeling framework for a nuclear reactor. The point kinetic equations are mathematically characterized as stiff, occasionally nonlinear, ordinary differential equations, posing significant challenges when numerical solutions are sought and traditionally resulting in the need for smaller time step intervals within various computational schemes. In light of the above realization, the present paper proposes a new discretization method inspired by system-theoretic notions and technically based on a combination of the matrix exponential method (MEM) and the First-Order Hold (FOH) assumption. Under the proposed time discretization structure, the sampled-data representation of the nonlinear point kinetic system of equations is derived. The performance of the proposed time discretization procedure is evaluated using several case studies with sinusoidal reactivity profiles and multiple input examples (reactivity and neutron source function). It is shown, that by applying the proposed method under a First-Order Hold for the neutron density and the precursor concentrations at each time step interval, the stiffness problem associated with the point kinetic equations can be adequately addressed and resolved. Finally, as evidenced by the aforementioned detailed simulation studies, the proposed method retains its validity and accuracy for a wide range of reactor operating conditions, including large sampling periods dictated by physical and/or technical limitations associated with the current state of sensor and

ENERGY STAR Certified Commercial Hot Food Holding Cabinet

Data.gov (United States)

U.S. Environmental Protection Agency — Certified models meet all ENERGY STAR requirements as listed in the Version 2.0 ENERGY STAR Program Requirements for Commercial Hot Food Holding Cabinets that are...

Impact of cash conversion cycle on cash holding – A study on FMCG sector

Directory of Open Access Journals (Sweden)

Somnath Das

2017-11-01

Full Text Available In today’s environment, cash conversion cycle is randomly used as a measure of liquidity of the organizations. Cash conversion cycle is considered as the length of time between raw-materials and collection of cash from debtors. It can be used as a benchmarking competitors or comparing companies. On the other hand, Cash holding is one of the most important financial decisions that a manager has to make in any organization. Some organizations hold more cash and some organizations hold less cash. In this study, we perform a survey to make a relationship between Cash Conversion Cycle and Cash Holding.

Stock Liquidity and Corporate Cash Holdings: Feedback and the Cash as Ammunition Hypothesis

OpenAIRE

Nyborg, Kjell G; Wang, Zexi

2013-01-01

The paper contributes to the literature on corporate cash holdings by showing that there is a financial markets channel that affects corporations’ cash holdings. Leaning on the literature on stock price feedback to firm fundamentals, we advance the hypothesis that firms with more liquid stocks hold more cash, ceteris paribus, as ammunition to defend against negative cascades or stimulate positive ones. This contrasts with an alternative view that firms with more liquid stocks are less financi...

Do More Economists Hold Stocks?

DEFF Research Database (Denmark)

Christiansen, Charlotte; Joensen, Juanna Schröter; Rangvid, Jesper

A unique data set enables us to test the hypothesis that more economists than otherwise identical investors hold stocks due to informational advantages. We confirm that economists have a significantly higher probability of participating in the stock market than investors with any other education......, even when controlling for several background characteristics. We make use of a large register-based panel data set containing detailed information on the educational attainments and various financial and socioeconomic variables. We model the stock market participation decision by the probit model...

Diverse Presentation of Breath Holding Spells: Two Case Reports with Literature Review

Directory of Open Access Journals (Sweden)

Geetanjali Rathore

2013-01-01

Full Text Available Breath holding spells are a common and dramatic form of syncope and anoxic seizure in infancy. They are usually triggered by an emotional stimuli or minor trauma. Based on the color change, they are classified into 3 types, cyanotic, pallid, and mixed. Pallid breath holding spells result from exaggerated, vagally-mediated cardiac inhibition, whereas the more common, cyanotic breathholding spells are of more complex pathogenesis which is not completely understood. A detailed and accurate history is the mainstay of diagnosis. An EKG should be strongly considered to rule out long QT syndrome. Spontaneous resolution of breath-holding spells is usually seen, without any adverse developmental and intellectual sequelae. Rare cases of status epilepticus, prolonged asystole, and sudden death have been reported. Reassurance and education is the mainstay of therapy. Occasionally, pharmacologic intervention with iron, piracetam; atropine may be of benefit. Here we present 2 cases, one of each, pallid and cyanotic breath holding spells.

Planning for positive clinical & financial returns with telemonitoring.

Science.gov (United States)

Wright, Kristy

2003-10-01

Telemonitoring is a burgeoning market in the home care industry. Making the decision to invest in telemonitoring technology can be difficult in the best situations. The financial investment is significant, the risks can be high, and the need to achieve a positive return is critical to future success. In spite of the risks, this relatively new technology in home care holds the promise for the redefinition of the industry.

Use of mobile technology in a community mental health setting.

Science.gov (United States)

Glick, Gretl; Druss, Benjamin; Pina, Jamie; Lally, Cathy; Conde, Mark

2016-10-01

mHealth holds promise in transforming care for people with serious mental illness (SMI) and other disadvantaged populations. However, information about the rates of smartphone ownership and usage of mobile health apps among people with SMI is limited. The objective of this research is to examine the current ownership, usage patterns, and existing barriers to mobile health interventions for people with SMI treated in a public sector community mental health setting and to compare the findings with national usage patterns from the general population. A survey was conducted to determine rates of ownership of smartphone devices among people with SMI. Surveys were administered to 100 patients with SMI at an outpatient psychiatric clinic. Results were compared with respondents to the 2012 Pew Survey of mobile phone usage. A total of 85% of participants reported that they owned a cell phone; of those, 37% reported that they owned a smartphone, as compared with 53% of respondents to the Pew Survey and 44% of socioeconomically disadvantaged respondents to the Pew Survey. While cell phone ownership is common among people with SMI, their adoption of smartphone technology lags behind that of the general population primarily due to cost barriers. Efforts to use mHealth in these populations need to recognize current mobile ownership patterns while planning for anticipated expansion of new technologies to poor populations as cost barriers are reduced in the coming years. © The Author(s) 2015.

Venezuela and Chavez: What the Future Holds...

Science.gov (United States)

2010-04-01

government made public 26 presidential decrees that had been enacted. These acts: ...covered such areas as tourism , railways, social security, and...great prosperity or a harbinger of doom to the region, and for this reason the United States must prepare for the many paths that the future holds

Biosketch Ashok Venkitaraman holds the Ursula Zoellner ...

Indian Academy of Sciences (India)

ashok

Ashok Venkitaraman holds the Ursula Zoellner Professorship of Cancer Research at the University of Cambridge, and is the Director of the Medical Research Council. (MRC) Cancer Cell Unit there. He learnt and practiced medicine at the Christian. Medical College, Vellore, before completing his Ph.D. at University College ...

Information technology investments must deliver value

International Nuclear Information System (INIS)

Schulz, Y.

1998-01-01

The value of information technology (IT) management for the petroleum industry was discussed. There are currently two points of view regarding the subject. Adherents of one view hold that the strategic uses of information technology are relevant to the oil and gas industry, while those opposed find no demonstrated connection between information technology investments and business results. This paper addresses the impact of the information paradox, but maintains that information technology is not only valuable but essential to the oil and gas industry. This paper maintains that whenever it is perceived as being of limited use and too expensive, it is usually because it is not well managed. Value management can and should lead to superior outcomes. Neither exploration, nor drilling nor production, nor marketing could exist without information technology as the value is imperative. To further make the case, the nature of information technology value management and the strategies required to achieve value from information technology are reviewed. figs

CRISPR/Cas9 Genome Editing: A Promising Tool for Therapeutic Applications of Induced Pluripotent Stem Cells.

Science.gov (United States)

Zhang, Yanli; Sastre, Danuta; Wang, Feng

2018-01-01

Induced pluripotent stem cells hold tremendous potential for biological and therapeutic applications. The development of efficient technologies for targeted genome alteration of stem cells in disease models is a prerequisite for utilizing stem cells to their full potential. The revolutionary technology for genome editing known as the clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 9 (Cas9) system is recently recognized as a powerful tool for editing DNA at specific loci. The ease of use of the CRISPR-Cas9 technology will allow us to improve our understanding of genomic variation in disease processes via cellular and animal models. More recently, this system was modified to repress (CRISPR interference, CRISPRi) or activate (CRISPR activation, CRISPRa) gene expression without alterations in the DNA, which amplified the scope of applications of CRISPR systems for stem cell biology. Here, we highlight latest advances of CRISPR-associated applications in human pluripotent stem cells. The challenges and future prospects of CRISPR-based systems for human research are also discussed. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Automated daily breath hold stability measurements by real-time imaging in radiotherapy of breast cancer

NARCIS (Netherlands)

De Boer, Hans C J; Van Den Bongard, Desirée J G; van Asselen, B

2016-01-01

Background and purpose Breath hold is increasingly used for cardiac sparing in left-sided breast cancer irradiation. We have developed a fast automated method to verify breath hold stability in each treatment fraction. Material and methods We evaluated 504 patients treated with breath hold. Moderate

Pengaruh Holding Time Terhadap Kekeruhan Pada Sampel Air Sungai Babura Dengan Metode Turbidimetri

OpenAIRE

Ashari, Dian

2010-01-01

Turbidity define the water optic determined based on amount of lihgts absorbed by materials in water. Turbidity caused by organic and inorganic materials which suspended and solved (such as mud and smooth sand), also organic and inorganic materials which in form of plankton and other microorganism. In this case, I study about holding time influence to turbidity, on trial this show very influencing a period of holding time to turbidity. Where a period of holding time at maximum turbidity sampl...

26 CFR 53.4943-7 - Special rules for readjustments involving grandfathered holdings.

Science.gov (United States)

2010-04-01

... in Z will represent 50% of the fair market value of the outstanding Z stock. (ii) Under the... 26 Internal Revenue 17 2010-04-01 2010-04-01 false Special rules for readjustments involving... Excess Business Holdings § 53.4943-7 Special rules for readjustments involving grandfathered holdings. (a...

41 CFR 109-1.5202 - Establishment of a personal property holdings baseline.

Science.gov (United States)

2010-07-01

... personal property holdings baseline. 109-1.5202 Section 109-1.5202 Public Contracts and Property Management...-1.5202 Establishment of a personal property holdings baseline. (a) If the contractor is a new... baseline or may perform a complete physical inventory of all personal property. This physical inventory is...

Makification: Towards a Framework for Leveraging the Maker Movement in Formal Education

Science.gov (United States)

Cohen, Jonathan; Jones, W. Monty; Smith, Shaunna; Calandra, Brendan

2017-01-01

Maker culture is part of a burgeoning movement in which individuals leverage modern digital technologies to produce and share physical artifacts with a broader community. Certain components of the maker movement, if properly leveraged, hold promise for transforming formal education in a variety of contexts. The authors here work towards a…

Intentional ICT: Curriculum, Education and Development. IBE Working Papers on Curriculum Issues No. 17

Science.gov (United States)

Lubin, Ian A.

2016-01-01

Information and communication technologies (ICT) are being utilized extensively in education and have become an essential aspect of both formal and informal learning worldwide. Related to their widespread availability and use in education, it is suggested that ICT hold tremendous promise for society at large, and in particular, in shaping social…

Imaginaries of nuclear energy in the Portuguese parliament: Between promise, risk, and democracy.

Science.gov (United States)

Santos Pereira, Tiago; Carvalho, António; Fonseca, Paulo F C

2017-04-01

This article explores the evolution of the nuclear energy debate and its associated controversies in the Portuguese parliament. The analysis focuses on the dictatorial regime of the New State (from the beginning of the nuclear program in 1951 until the 1974 revolution) and on the democratic period (post-1974). Portugal, as an exporting country of uranium minerals, significantly invested in the development of a national capacity in nuclear research, but never developed an endogenous nuclear power infrastructure. Through the analysis of parliamentary debates, this article characterizes the dynamic evolution of the Portuguese sociotechnical imaginary on nuclear energy and technology interlinked with ambivalent representations, including the promise of nuclear energy as key for the constitution of a technological Nation or as prompting new sociotechnical risks.

78 FR 36189 - Formations of, Acquisitions by, and Mergers of Savings and Loan Holding Companies

Science.gov (United States)

2013-06-17

... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Savings and Loan Holding... CFR part 239), and all other applicable statutes and regulations to become a savings and loan holding... savings association and nonbanking companies owned by the savings and loan holding company, including the...

An exploratory study of engagement in a technology-supported substance abuse intervention

Directory of Open Access Journals (Sweden)

VanDeMark Nancy R

2010-06-01

Full Text Available Abstract Background The continuing gap between the number of people requiring treatment for substance use disorders and those receiving treatment suggests the need to develop new approaches to service delivery. Meanwhile, the use of technology to provide counseling and support in the substance abuse field is exploding. Despite the increase in the use of technology in treatment, little is known about the impact of technology-supported interventions on access to services for substance use disorders. The E-TREAT intervention brings together the evidence-based practice of Motivational Interviewing and theories of Persuasive Technology to sustain clients' motivation to change substance use behaviors, provide support for change, and facilitate continuity across treatment settings. Methods This study used descriptive statistics, tests of statistical significance, and logistic regression to explore the characteristics and perceptions of the first 157 people who agreed to participate in E-TREAT and the predictors of their active engagement in E-TREAT services. In addition, responses to open-ended questions about the participants' experiences with the intervention were analyzed. Results The data reveal that clients who engaged in E-TREAT were more likely than those who did not engage to be female, have children and report a positive relationship with their recovery coach, and were less likely to have completed treatment for a substance use disorder in the past. A majority of people engaging in E-TREAT reported that it was helpful to talk with others with similar problems and that the program assisted them in developing a sense of community. Conclusions The authors conclude that technology-assisted interventions hold promise in expanding access to treatment for substance use disorders especially for women and parents. Further, the characteristics of the relationship with a coach or helper may be critical to engagement in technology-supported interventions

Nanomedicine: Perspective and promises with ligand-directed molecular imaging

Energy Technology Data Exchange (ETDEWEB)

Pan Dipanjan [Department of Medicine, Washington University Medical School, St. Louis, MO (United States)], E-mail: dipanjan@wustl.edu; Lanza, Gregory M.; Wickline, Samuel A. [Department of Medicine, Washington University Medical School, St. Louis, MO (United States); Caruthers, Shelton D. [Department of Medicine, Washington University Medical School, St. Louis, MO (United States); Philips Healthcare, Andover, MA (United States)], E-mail: scaruthers@cmrl.wustl.edu

2009-05-15

Molecular imaging and targeted drug delivery play an important role toward personalized medicine, which is the future of patient management. Of late, nanoparticle-based molecular imaging has emerged as an interdisciplinary area, which shows promises to understand the components, processes, dynamics and therapies of a disease at a molecular level. The unprecedented potential of nanoplatforms for early detection, diagnosis and personalized treatment of diseases, have found application in every biomedical imaging modality. Biological and biophysical barriers are overcome by the integration of targeting ligands, imaging agents and therapeutics into the nanoplatform which allow for theranostic applications. In this article, we have discussed the opportunities and potential of targeted molecular imaging with various modalities putting a particular emphasis on perfluorocarbon nanoemulsion-based platform technology.

Nanomedicine: Perspective and promises with ligand-directed molecular imaging

International Nuclear Information System (INIS)

Pan Dipanjan; Lanza, Gregory M.; Wickline, Samuel A.; Caruthers, Shelton D.

2009-01-01

Molecular imaging and targeted drug delivery play an important role toward personalized medicine, which is the future of patient management. Of late, nanoparticle-based molecular imaging has emerged as an interdisciplinary area, which shows promises to understand the components, processes, dynamics and therapies of a disease at a molecular level. The unprecedented potential of nanoplatforms for early detection, diagnosis and personalized treatment of diseases, have found application in every biomedical imaging modality. Biological and biophysical barriers are overcome by the integration of targeting ligands, imaging agents and therapeutics into the nanoplatform which allow for theranostic applications. In this article, we have discussed the opportunities and potential of targeted molecular imaging with various modalities putting a particular emphasis on perfluorocarbon nanoemulsion-based platform technology.

The Effect of Holding a Research Chair on Scientists’ Impact

Energy Technology Data Exchange (ETDEWEB)

Mirnezami, S.R.; Beaudry, C.

2016-07-01

This paper examines the effect of holding Canada Research Chair (CRC) on a scientist’s number of citations as a measure of research impact, based on an econometric analysis with combined data on Quebec scientists’ funding and journal publication. Using Generalized Least Square (GLS) method for regression analysis, the results show that holding either tier-1 or tier- 2 of CRC significantly and positively results in conducting research with higher impact. This finding, however, does not necessarily imply that the others are the lesser scientists. (Author)

Triaxial slide-hold-slide shear experiment of sedimentary rock under drain condition

International Nuclear Information System (INIS)

Kishida, Kiyoshi; Yano, Takao; Elsworth, Derek; Yasuhara, Hideaki; Nakashima, Shinichiro

2011-01-01

When discussing the mechanical and hydro-mechanical properties of rock masses under the long-term holding, the variation of rock structure and the change of shear band condition should be discussed in considering the effect of thermal and chemical influences. In this research, the triaxial shear experiment under drain condition was conducted through sedimentary rock, and in the residual stress state, the slide-hold-slide processes were applied to these triaxial experiments. The experiments were carried out in 3 kinds of confining conditions and 2 kinds of thermal conditions. Consequently, the healing phenomena can be observed and the shear strength recovery is also confirmed in process of the holding time. (author)

Technological Innovations in Forensic Genetics

DEFF Research Database (Denmark)

Wienroth, Matthias; Morling, Niels; Williams, Robin

2014-01-01

This paper discusses the nature of four waves of technological innovations in forensic genetics alongside the social, legal and ethical aspect of these innovations. It emphasises the way in which technological advances and their socio-legal frameworks are co-produced, shaping technology...... expectations, social identities, and legal institutions. It also considers how imagined and actual uses of forensic genetic technologies are entangled with assertions about social order, affirmations of common values and civil rights, and promises about security and justice. Our comments seek to encourage...

Do biological-based strategies hold promise to biofouling control in MBRs?

KAUST Repository

Malaeb, Lilian; Le-Clech, Pierre; Vrouwenvelder, Johannes S.; Ayoub, George M.; Saikaly, Pascal

2013-01-01

. The reason for the slow advancement in successful control of biofouling is largely attributed to the complex interactions of involved biological compounds and the lack of representative-for-practice experimental approaches to evaluate potential effective

New technology of CRDM-CS

International Nuclear Information System (INIS)

Yasushi Nozaki; Hiroyuki Ukon; Toshiaki Matsumura; Yoshihiro Sakurai; Sigenori Hatazawa; Hitoshi Yamagishi; Katsuji Kaneizumi; Hisashi Yasuda

2005-01-01

Control Rod Drive Mechanism Control System (CRDM-CS) for PWR Nuclear Power Plant was developed as a domestic product in 1975 and it has been applied to the commercial power plants. Since then, the CRDM-CS has been continuously improved through applying a double-hold-system, an intensified monitoring system, etc. As the result of these modifications unexpected rod drops have never occurred more than ten years in Japanese PWR plants. The system is still so high reliable, however, the technologies of employed devices are old-fashioned and we face on the difficulty to keep spare-parts these days. On the other hand, there are new movements to seek after the plant life extension of 60 years. These situations require a modernized CRDM-CS to accomplish the reliability in accordance to the plant life extension. to comply the above-mentioned object we developed a new CRDM-CS applied with following technologies; 1) Digitalized logic cabinet, 2) I.G.B.T in the main circuit of power cabinet, 3) Standardized cabinet by employing the unit structure, 4) Unnecessary DC hold power cabinet. These measures can play an important role in cost cutting and space reduction in replacing CRDM-CS. The concepts in developing the new CRDM-CS, the applied technologies to the power cabinet, the system structure and characteristics of the logic cabinet and the outline of verification test and result are discussed in this paper. (authors)

Novel Microbial Electrochemical Technologies and Microorganisms for Power Generation and Desalination

KAUST Repository

Chehab, Noura A.

2014-12-01

Global increases in water demand and decreases in both the quantity and quality of fresh water resources have served as the major driving forces to develop sustainable use of water resources. One viable alternative is to explore non-traditional (impaired quality) water sources such as wastewater and seawater. The current paradigm for wastewater treatment is based on technologies that are energy intensive and fail to recover the potential resources (water and energy) in wastewater. Also, conventional desalination technologies like reverse osmosis (RO) are energy intensive. Therefore, there is a need for the development of sustainable wastewater treatment and desalination technologies for practical applications. Processes based on microbial electrochemical technologies (METs) such as microbial fuel cells (MFCs), microbial electrolysis cells (MECs) and microbial desalination cells (MDCs) hold promise for the treatment of wastewater with recovery of the inherent energy, and MDCs could be used for both desalination of seawater and energy recovery. METs use anaerobic bacteria, referred to as exoelectrogens, that are capable of transferring electrons exogenously to convert soluble organic matter present in the wastewater directly into an electrical current to produce electrical power (MFC and MDC) or biogas (MEC). In my dissertation, I investigated the three types of METs mentioned above to: 1) have a better insight on the effect of 4 oxygen intrusion on the microbial community structure and performance of air-cathode MFCs; 2) improve the desalination efficiency of air-cathode MDCs using ion exchange resins (IXRs); and 3) enrich for extremophilic exoelectrogens from the Red Sea brine pool using MECs. The findings from these studies can shape further research aimed at developing more efficient air-cathode MFCs for practical applications, a more efficient integrated IXRMDC configuration that can be used as a pre-treatment to RO, and exploring extreme environments as a

Curcumin is a promising inhibitor of genotype 2 porcine reproductive and respiratory syndrome virus infection.

Science.gov (United States)

Du, Taofeng; Shi, Yunpeng; Xiao, Shuqi; Li, Na; Zhao, Qin; Zhang, Angke; Nan, Yuchen; Mu, Yang; Sun, Yani; Wu, Chunyan; Zhang, Hongtao; Zhou, En-Min

2017-10-10

Porcine reproductive and respiratory syndrome virus (PRRSV) could lead to pandemic diseases and huge financial losses to the swine industry worldwide. Curcumin, a natural compound, has been reported to serve as an entry inhibitor of hepatitis C virus, chikungunya virus and vesicular stomatitis virus. In this study, we investigated the potential effect of curcumin on early stages of PRRSV infection. Curcumin inhibited infection of Marc-145 cells and porcine alveolar macrophages (PAMs) by four different genotype 2 PRRSV strains, but had no effect on the levels of major PRRSV receptor proteins on Marc-145 cells and PAMs or on PRRSV binding to Marc-145 cells. However, curcumin did block two steps of the PRRSV infection process: virus internalization and virus-mediated cell fusion. Our results suggested that an inhibition of genotype 2 PRRSV infection by curcumin is virus strain-independent, and mainly inhibited by virus internalization and cell fusion mediated by virus. Collectively, these results demonstrate that curcumin holds promise as a new anti-PRRSV drug.

76 FR 13438 - In the Matter of AdAl Group, Inc., Com/Tech Communications Technologies, Inc., Dialog Group, Inc...

Science.gov (United States)

2011-03-11

... Communications Technologies, Inc., Dialog Group, Inc., Eurogas, Inc., Golden Books Family Entertainment, Inc. (n/k/a GB Holdings Liquidation, Inc.), Information Management Technologies Corporation, Interiors, Inc... accurate information concerning the securities of Com/Tech Communications Technologies, Inc. because it has...

Realizing the promises of marine biotechnology

NARCIS (Netherlands)

Luiten, EEM; Akkerman, [No Value; Koulman, A; Kamermans, P; Reith, H; Barbosa, MJ; Sipkema, D; Wijffels, RH

High-quality research in the field of marine biotechnology is one of the key-factors for successful innovation in exploiting the vast diversity of marine life. However, fascinating scientific research with promising results and claims on promising potential applications (e.g. for pharmaceuticals,

Realizing the promises of marine biotechnology

NARCIS (Netherlands)

Luiten, E.E.M.; Akkerman, I.; Koulman, A.; Kamermans, P.; Reith, H.; Barbosa, M.J.; Sipkema, D.; Wijffels, R.H.

2003-01-01

High-quality research in the field of marine biotechnology is one of the key-factors for successful innovation in exploiting the vast diversity of marine life. However, fascinating scientific research with promising results and claims on promising potential applications (e.g. for pharmaceuticals,

Benevolent technotopias and hitherto unimaginable meats: Tracing the promises of in vitro meat.

Science.gov (United States)

Jönsson, Erik

2016-10-01

Today, in vitro (Latin: in glass) meat researchers strive to overhaul meat production technologies by producing meat outside animal bodies, primarily by culturing cells. In the process, meat should become healthier, more environmentally friendly and kinder to animals. In this article, I scrutinize (and problematize) this promissory discourse by examining the world that proponents envision alongside the world from which promises emerge. First, I trace the increasing number of publications striving to pinpoint the nature of in vitro meat to unveil the creation of an in vitro meat canon wherein perceived possibilities become taken for granted. Second, I investigate how the promissory discourse is often relatively silent on key aspects of how this technology could remake the world. Wet laboratories, animals and end products become foregrounded at the expense of political economy and the biophysical properties of cultured cells. Thus, questions concerning how funding requirements shape representations of this new technology, together with in vitro meat's particular socio-spatial and socio-ecological implications, become problematically de-emphasized.

Political Reputations and Campaign Promises

OpenAIRE

Aragones, Enriqueta; Palfrey, Thomas R.; Postlewaite, Andrew

2006-01-01

We analyze conditions under which candidates' reputations may affect voters' beliefs over what policy will be implemented by the winning candidate of an election. We develop a model of repeated elections with complete information in which candidates are purely ideological. We analyze an equilibrium in which voters' strategies involve a credible threat to punish candidates who renege on their campaign promises and in which all campaign promises are believed by voters and honored by candidates....

Advancing chimeric antigen receptor T cell therapy with CRISPR/Cas9.

Science.gov (United States)

Ren, Jiangtao; Zhao, Yangbing

2017-09-01

The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 (CRISPR/Cas9) system, an RNA-guided DNA targeting technology, is triggering a revolution in the field of biology. CRISPR/Cas9 has demonstrated great potential for genetic manipulation. In this review, we discuss the current development of CRISPR/Cas9 technologies for therapeutic applications, especially chimeric antigen receptor (CAR) T cell-based adoptive immunotherapy. Different methods used to facilitate efficient CRISPR delivery and gene editing in T cells are compared. The potential of genetic manipulation using CRISPR/Cas9 system to generate universal CAR T cells and potent T cells that are resistant to exhaustion and inhibition is explored. We also address the safety concerns associated with the use of CRISPR/Cas9 gene editing and provide potential solutions and future directions of CRISPR application in the field of CAR T cell immunotherapy. As an integration-free gene insertion method, CRISPR/Cas9 holds great promise as an efficient gene knock-in platform. Given the tremendous progress that has been made in the past few years, we believe that the CRISPR/Cas9 technology holds immense promise for advancing immunotherapy.

Advancing chimeric antigen receptor T cell therapy with CRISPR/Cas9

Directory of Open Access Journals (Sweden)

Jiangtao Ren

2017-04-01

Full Text Available ABSTRACT The clustered regularly interspaced short palindromic repeats (CRISPR/CRISPR-associated 9 (CRISPR/Cas9 system, an RNA-guided DNA targeting technology, is triggering a revolution in the field of biology. CRISPR/Cas9 has demonstrated great potential for genetic manipulation. In this review, we discuss the current development of CRISPR/Cas9 technologies for therapeutic applications, especially chimeric antigen receptor (CAR T cell-based adoptive immunotherapy. Different methods used to facilitate efficient CRISPR delivery and gene editing in T cells are compared. The potential of genetic manipulation using CRISPR/Cas9 system to generate universal CAR T cells and potent T cells that are resistant to exhaustion and inhibition is explored. We also address the safety concerns associated with the use of CRISPR/Cas9 gene editing and provide potential solutions and future directions of CRISPR application in the field of CAR T cell immunotherapy. As an integration-free gene insertion method, CRISPR/Cas9 holds great promise as an efficient gene knock-in platform. Given the tremendous progress that has been made in the past few years, we believe that the CRISPR/Cas9 technology holds immense promise for advancing immunotherapy.

Holding back, intimacy, and psychological and relationship outcomes among couples coping with prostate cancer.

Science.gov (United States)

Manne, Sharon L; Kissane, David; Zaider, Talia; Kashy, Deborah; Lee, David; Heckman, Carolyn; Virtue, Shannon Myers

2015-10-01

The present study evaluated intimacy as a mechanism for the effects of holding back sharing concerns about cancer on couples' psychological distress, well-being, and marital satisfaction using the actor-partner interdependence model (APIM), and evaluated 2 possible moderators of these associations: the number of patient and spouse cancer concerns. We had 139 men treated for localized prostate cancer in the past year and their spouses complete surveys about holding back sharing cancer concerns, intimacy, distress, and relationship satisfaction, as well as patient and spouse cancer concerns. APIM-indicated that the association between holding back sharing concerns, and patient and spouse distress, well-being, and relationship satisfaction could be partially accounted for by their influence on patient and spouse perceptions of relationship intimacy. The number of cancer concerns did not moderate the mediational model. Holding back has strong associations with both partners' well-being and distress. Holding back sharing concerns was particularly detrimental for couples' intimacy and relationship satisfaction. (c) 2015 APA, all rights reserved).

The Promise and Challenges of Ultra High Bypass Ratio Engine Technology and Integration

Science.gov (United States)

Hughes, Chris

2011-01-01

In this presentation, an overview of the research being conducted by the ERA Project in Ultra High Bypass aircraft propulsion and in partnership with Pratt & Whitney with their Geared TurboFan (GTF) is given. The ERA goals are shown followed by a discussion of what areas need to be addressed on the engine to achieve the goals and how the GTF is uniquely qualified to meet the goals through a discussion of what benefits the cycle provides. The first generation GTF architecture is then shown highlighting the areas of collaboration with NASA, and the fuel burn, noise and emissions reductions possible based on initial static ground test and flight test data of the first GTF engine. Finally, a 5 year technology roadmap is presented focusing on Ultra High Bypass propulsion technology research areas that are being pursued and being planned by ERA and P&W under their GTF program.

31 CFR 346.5 - Limitation on holdings.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Limitation on holdings. 346.5 Section 346.5 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE... deducted in any one year be in equal amounts. While it is permissible for an eligible married couple to...

A Ship Cargo Hold Inspection Approach Using Laser Vision Systems

OpenAIRE

SHEN Yang; ZHAO Ning; LIU Haiwei; MI Chao

2013-01-01

Our paper represents a vision system based on the laser measurement system (LMS) for bulk ship inspection. The LMS scanner with 2-axis servo system is installed on the ship loader to build the shape of the ship. Then, a group of real-time image processing algorithms are implemented to compute the shape of the cargo hold, the inclination angle of the ship and the relative position between the ship loader and the cargo hold. Based on those computed inspection data of the ship, the ship loader c...

The future of drug discovery: enabling technologies for enhancing lead characterization and profiling therapeutic potential.

Science.gov (United States)

Janero, David R

2014-08-01

Technology often serves as a handmaiden and catalyst of invention. The discovery of safe, effective medications depends critically upon experimental approaches capable of providing high-impact information on the biological effects of drug candidates early in the discovery pipeline. This information can enable reliable lead identification, pharmacological compound differentiation and successful translation of research output into clinically useful therapeutics. The shallow preclinical profiling of candidate compounds promulgates a minimalistic understanding of their biological effects and undermines the level of value creation necessary for finding quality leads worth moving forward within the development pipeline with efficiency and prognostic reliability sufficient to help remediate the current pharma-industry productivity drought. Three specific technologies discussed herein, in addition to experimental areas intimately associated with contemporary drug discovery, appear to hold particular promise for strengthening the preclinical valuation of drug candidates by deepening lead characterization. These are: i) hydrogen-deuterium exchange mass spectrometry for characterizing structural and ligand-interaction dynamics of disease-relevant proteins; ii) activity-based chemoproteomics for profiling the functional diversity of mammalian proteomes; and iii) nuclease-mediated precision gene editing for developing more translatable cellular and in vivo models of human diseases. When applied in an informed manner congruent with the clinical understanding of disease processes, technologies such as these that span levels of biological organization can serve as valuable enablers of drug discovery and potentially contribute to reducing the current, unacceptably high rates of compound clinical failure.

EXCESS CASH HOLDINGS DAN KEPEMILIKAN INSTITUSIONAL PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BEI

Directory of Open Access Journals (Sweden)

Yessica Tria Christina

2014-02-01

Full Text Available This research provides an empirical evidence about the effect of institutional ownerships as a proxy of information transparancy on excess cash holdings. Manufacture companies listed on BEI from years 2002 to 2011 are employed. The results show that the higher the proportion of institutional ownership, the lower the excess cash holdings. Informational transparancy, as one of the requirements of good corporate governance, can in fact lower the chance of aggrevating the manager’s behavior to practice excess cash holdings that can lower the company’s efficiency.

Embodied cognition, abstract concepts, and the benefits of new technology for implicit body manipulation

Science.gov (United States)

Dijkstra, Katinka; Eerland, Anita; Zijlmans, Josjan; Post, Lysanne S.

2014-01-01

Current approaches on cognition hold that concrete concepts are grounded in concrete experiences. There is no consensus, however, as to whether this is equally true for abstract concepts. In this review we discuss how the body might be involved in understanding abstract concepts through metaphor activation. Substantial research has been conducted on the activation of common orientational metaphors with bodily manipulations, such as “power is up” and “more is up” representations. We will focus on the political metaphor that has a more complex association between the concept and the concrete domain. However, the outcomes of studies on this political metaphor have not always been consistent, possibly because the experimental manipulation was not implicit enough. The inclusion of new technological devices in this area of research, such as the Wii Balance Board, seems promising in order to assess the groundedness of abstract conceptual spatial metaphors in an implicit manner. This may aid further research to effectively demonstrate the interrelatedness between the body and more abstract representations. PMID:25191282

Information and Communication Technology Inside Out

DEFF Research Database (Denmark)

Riis, Søren

2017-01-01

Information and communication technology (ICT) has become the great technological fix of our time and not the least in the education system. There seems to be no end to the hype of ICT and the accompanying promises that education will be revolutionized—“smart” pupils will be made and the so...

Radiotherapy of lung cancer: the inspiration breath hold with a spirometric monitoring

International Nuclear Information System (INIS)

Garcia, R.; Oozeer, R.; Le Thanh, H.; Chastel, D.; Doyen, J.C.; Chauvet, B.; Reboul, F.

2002-01-01

A CT acquisition during a free breathing examination generates images of poor quality. It creates an uncertainty on the reconstructed gross tumour volume and dose distribution. The aim of this study is to test the feasibility of a breath hold method applied in all preparation and treatment days. Five patients received a thoracic radiotherapy with the benefit of this procedure. The breathing of the patient was measured with a spirometer. The patient was coached to reproduce a constant level of breath-hold in a deep inspiration. Video glasses helped the patients to fix the breath-hold at the reference level. The patients followed the coaching during preparation and treatment, without any difficulty. The better quality of the CT reconstructed images resulted in an easier contouring. No movements of the gross tumour volume lead to a better coverage. The deep breath hold decreased the volume of irradiated lung. This method improves the reproducibility of the thoracic irradiation. The decrease of irradiated lung volume offers prospects in dose escalation and intensity modulation radiotherapy. (authors)

Skin-to-skin holding in the neonatal intensive care unit influences maternal milk volume.

Science.gov (United States)

Hurst, N M; Valentine, C J; Renfro, L; Burns, P; Ferlic, L

1997-01-01

To evaluate the effect of early initiation of skin-to-skin (STS) holding on lactation, we compared 24-hour milk volumes of mothers of ventilated low birth weight infants in an STS group to mothers in a non-STS control group. Mean 24-hour milk volumes at 2, 3, and 4 weeks after delivery of mothers participating in STS holding were compared with those of a retrospective control group from the 12-month period immediately preceding the introduction of STS holding in the neonatal intensive care unit. A repeated-measures analysis of variance adjusting for baseline volumes (1 week after delivery) was used to evaluate the difference in milk volumes between STS and control groups. Sixteen mothers initiated STS holding during the 2-month study period. Eight mothers met study criteria by initiating STS holding during the first 4 weeks after delivery. During a 2-week period the study group had a strong linear increase in milk volume in contrast to no indicative change of the control group's milk volume. STS holding of low birth weight infants initiated in the early intensive care phase can result in a significant increase in maternal milk volume, thereby overcoming the frequently seen insufficient lactation experienced by these mothers.

The Mobile Robot "Little Helper"

DEFF Research Database (Denmark)

Hvilshøj, Mads; Bøgh, Simon; Madsen, Ole

2009-01-01

Increased customer needs and intensified global competition require intelligent and flexible automation. The interaction technology mobile robotics addresses this, so it holds great potential within the industry. This paper presents the concepts, ideas and working principles of the mobile robot...... this show promising results regarding industrial integration, exploitation and maturation of mobile robotics....

Social Media Use, Friendship Quality, and the Moderating Role of Anxiety in Adolescents with Autism Spectrum Disorder

Science.gov (United States)

van Schalkwyk, Gerrit I.; Marin, Carla E.; Ortiz, Mayra; Rolison, Max; Qayyum, Zheala; McPartland, James C.; Lebowitz, Eli R.; Volkmar, Fred R.; Silverman, Wendy K.

2017-01-01

Social media holds promise as a technology to facilitate social engagement, but may displace offline social activities. Adolescents with ASD are well suited to capitalize on the unique features of social media, which requires less decoding of complex social information. In this cross-sectional study, we assessed social media use, anxiety and…

Gamification Strategies in a Hybrid Exemplary College Course

Science.gov (United States)

Machajewski, Szymon

2017-01-01

Using technology in teaching and learning finds a wide adoption in recent years. 63.3% of chief academic leaders surveyed by the Babson Survey Research Group confirm that online education is critical to their long-term strategy. Modern engagement pedagogies, such as digital gamification, hold a promise of shaping student experience. While course…

Traditional Chinese Medicine for Refractory Nephrotic Syndrome: Strategies and Promising Treatments

Science.gov (United States)

Tu, Yuan-Chao

2018-01-01

Refractory nephrotic syndrome (RNS) is an immune-related kidney disease with poor clinical outcomes. Standard treatments include corticosteroids as the initial therapy and other immunosuppressants as second-line options. A substantial proportion of patients with RNS are resistant to or dependent on immunosuppressive drugs and often experience unremitting edema and proteinuria, cycles of remission and relapse, and/or serious adverse events due to long-term immunosuppression. Traditional Chinese medicine has a long history of treating complicated kidney diseases and holds great potential for providing effective treatments for RNS. This review describes the Chinese medical theories relating to the pathogenesis of RNS and discusses the strategies and treatment options using Chinese herbal medicine. Available preclinical and clinical evidence strongly supports the integration of traditional Chinese medicine and Western medicine for improving the outcome of RNS. Herbal medicine such as Astragalus membranaceus, Stephania tetrandra S. Moore, and Tripterygium wilfordii Hook F can serve as the alternative therapy when patients fail to respond to immunosuppression or as the complementary therapy to improve therapeutic efficacy and reduce side effects of immunosuppressive agents. Wuzhi capsules (Schisandra sphenanthera extract) with tacrolimus and tetrandrine with corticosteroids are two herb-drug combinations that have shown great promise and warrant further studies. PMID:29507594

Analysis of cash holding for measuring the efficiency of cash management: A study on IT sector

Directory of Open Access Journals (Sweden)

Somnath Das

2015-01-01

Full Text Available For measuring the efficiency of management of cash, cash holding is one of the most important financial decisions that the manager of the concerned organization, has to make in the organization. Basically, it is observed that the organization hold cash for future purposes is very negligible. If the organization invested cash in profitable securities then there is some flexibility but when it relates to the capital market holding cash is not advantageous. Generally two contradictory theories such as Trade-off theory and the Pecking order theory are considered for measuring the efficiency of cash management. In this study we generally observed measured the efficiency of Cash Management influenced by Cash Holding. We also measured whether cash holding of the organization is affected with the degree of financial leverage, size of the organization, investment and profitability. This study helps us to understand the influence of DFL, Investment and Size of the organization on Cash holding. Proper holding of cash in cash management can prevent the bankruptcy of any organization and also increases the efficiency of Cash or Liquidity management.

Effects of Holding Methods and Time on the Vitamin Contents of Five ...

African Journals Online (AJOL)

The five leafy vegetables are fair sources of thiamin, riboflavin and niacin. There were losses in the vitamins as holding time increased, regardless of the holding method employed. The rate of loss of vitamins was highest in Lot I (the unwrapped leaves that were kept in a shade both day and night). The rate of loss of vitamins ...

The promise of mixed-methods for advancing latino health research.

Science.gov (United States)

Apesoa-Varano, Ester Carolina; Hinton, Ladson

2013-09-01

Mixed-methods research in the social sciences has been conducted for quite some time. More recently, mixed-methods have become popular in health research, with the National Institutes of Health leading the impetus to fund studies that implement such an approach. The public health issues facing us today are great and they range from policy and other macro-level issues, to systems level problems to individuals' health behaviors. For Latinos, who are projected to become the largest minority group bearing a great deal of the burden of social inequality in the U.S., it is important to understand the deeply-rooted nature of these health disparities in order to close the gap in health outcomes. Mixed-methodology thus holds promise for advancing research on Latino heath by tackling health disparities from a variety of standpoints and approaches. The aim of this manuscript is to provide two examples of mixed methods research, each of which addresses a health topic of considerable importance to older Latinos and their families. These two examples will illustrate a) the complementary use of qualitative and quantitative methods to advance health of older Latinos in an area that is important from a public health perspective, and b) the "translation" of findings from observational studies (informed by social science and medicine) to the development and testing of interventions.

Disabling and Enabling Technologies for Learning in Higher Education for All: Issues and Challenges for Whom?

Directory of Open Access Journals (Sweden)

Sangeeta Bagga-Gupta

2016-10-01

Full Text Available Integration, inclusion, and equity constitute fundamental dimensions of democracy in post-World War II societies and their institutions. The study presented here reports upon the ways in which individuals and institutions both use and account for the roles that technologies, including ICT, play in disabling and enabling access for learning in higher education for all. Technological innovations during the 20th and 21st centuries, including ICT, have been heralded as holding significant promise for revolutionizing issues of access in societal institutions like schools, healthcare services, etc. (at least in the global North. Taking a socially oriented perspective, the study presented in this paper focuses on an ethnographically framed analysis of two datasets that critically explores the role that technologies, including ICT, play in higher education for individuals who are “differently abled” and who constitute a variation on a continuum of capabilities. Functionality as a dimension of everyday life in higher education in the 21st century is explored through the analysis of (i case studies of two “differently abled” students in Sweden and (ii current support services at universities in Sweden. The findings make visible the work that institutions and their members do through analyses of the organization of time and space and the use of technologies in institutional settings against the backdrop of individuals’ accountings and life trajectories. This study also highlights the relevance of multi-scale data analyses for revisiting the ways in which identity positions become framed or understood within higher education.

Non-nuclear power application of nuclear technology in Nigeria

International Nuclear Information System (INIS)

Funtua, I.I.

2008-01-01

Nuclear Technology applications are found in Food and Agriculture, Human Health, Water Resources, Industry, Environment, Education and Research.There are more potentials for the deployment of nuclear technology in more aspects of our life with needed economic development in Nigeria.Nuclear Technology plays and would continue to play vital role in Agriculture, Human health, Water resources and industry in Nigeria.Nuclear technologies have been useful in developmental efforts worldwide and for these to take hold, capacity building programmes must be expanded and the general public must have informed opinions about the benefits and risk associated with the technologies.This presentation gives an overview of nuclear technology applications in Nigeria in the following areas: Food and Agriculture, Human Health, Water Resources, Industry, Education and Research

Effective Holding of Scientific Olympiads for Medical Sciences Students: a Qualitative Study

Directory of Open Access Journals (Sweden)

Morteza Ghojazadeh

2015-12-01

Full Text Available Introduction: Due to the importance of holding effective scientific Olympiads for medical sciences students, this study aimed to evaluate experts’ viewpoints in regard to their necessity, costs, achievements, barriers and solutions. Methods: In this qualitative study, required data were collected using open-ended questions through self-development questionnaires, which were filled out by experts. Data were analyzed through content-analysis methods. To select participants, a purpose-based sampling method was applied up to the point of information saturation. Thus, this study was performed with 20 individuals. Results: The main necessity and philosophy of holding Olympiads expressed by the experts were: promoting health sector performance, extension of interrelationships between universities, development of scientific competition and incensement of students’ creativity. The majority of participants believed that the achievements of holding these Olympiads are negligible versus their costs. The most important barriers were: absence of appropriate relationships between universities, lack of proper support for holding these Olympiads, the low motivation of professors, noninterested students and the shortage of resources and facilities. Furthermore, the most important solutions included: performance evaluation of previous Olympiads, increasing incentives and motivations as well as suitable planning. Conclusion: According to experts’ viewpoints, although holding scientific Olympiads is necessary for medical students, during past years, the achievements of such Olympiads versus theirs costs seem negligible and there are lots of barriers in the path of achieving their goals and philosophy.

78 FR 56263 - HydroGen Corp., QueryObject Systems Corp., Security Intelligence Technologies, Inc., Skins, Inc...

Science.gov (United States)

2013-09-12

... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] HydroGen Corp., QueryObject Systems Corp., Security Intelligence Technologies, Inc., Skins, Inc., SLM Holdings, Inc., Spring Creek Healthcare Systems... securities of Security Intelligence Technologies, Inc. because it has not filed any periodic reports since...

Ultrasonication and food technology: A review

OpenAIRE

Ishrat Majid; Gulzar Ahmad Nayik; Vikas Nanda

2015-01-01

With increasing consumers demand and tightening of food and environmental regulations, traditional food-processing techniques have lost their optimum performance which gave rise to new and powerful technologies. Ultrasonic is a one of the fast, versatile, emerging, and promising non-destructive green technology used in the food industry from last few years. The ultrasound is being carried out in various areas of food technology namely crystallization, freezing, bleaching, degassing, extractio...

Ethics, Deafness, and New Medical Technologies

Science.gov (United States)

Hintermair, Manfred; Albertini, John A.

2005-01-01

In the last 50 years, several new technologies have become enormously important within the Deaf community and have helped significantly to improve deaf people's lives in a hearing world. Current public attention and admiration, however, seems unduly focused on medical technologies that promise to solve "the problem" of being deaf. One reason for…

77 FR 3774 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2012-01-25

..., Dupont, Indiana. River Valley Financial Bank, Madison, Indiana, the existing thrift subsidiary of... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company...

Do social factors influence investment behavior and performance? Evidence from mutual fund holdings

NARCIS (Netherlands)

Borgers, Arian; Derwall, J.M.M.; Koedijk, Kees; ter Horst, Jenke

2015-01-01

We study the economic significance of social dimensions in investment decisions by analyzing the holdings of U.S. equity mutual funds over the period 2004-2012. Using these holdings, we measure funds' exposures to socially sensitive stocks in order to answer two questions. What explains

Trend Definition or Holding Strategy: What Determines the Profitability of Candlestick Technical Trading Strategies?

OpenAIRE

Tsung-Hsun Lu; Yi-Chi Chen; Yu-Chin Hsu

2014-01-01

We ask what determines the profitability of candlestick patterns. Is it the definition of trend and/or the holding strategy that one uses in candlestick charting analysis? To answer this, we conduct a systematic investigation by considering three definitions of trend and four holding strategies. Based on the DJIA components data, we find that eight three-day reversal patterns with a Caginalp-Laurent holding strategy are profitable after we account for data-snooping bias. We also find that our...

Analysis of an inventory model for both linearly decreasing demand and holding cost

Science.gov (United States)

Malik, A. K.; Singh, Parth Raj; Tomar, Ajay; Kumar, Satish; Yadav, S. K.

2016-03-01

This study proposes the analysis of an inventory model for linearly decreasing demand and holding cost for non-instantaneous deteriorating items. The inventory model focuses on commodities having linearly decreasing demand without shortages. The holding cost doesn't remain uniform with time due to any form of variation in the time value of money. Here we consider that the holding cost decreases with respect to time. The optimal time interval for the total profit and the optimal order quantity are determined. The developed inventory model is pointed up through a numerical example. It also includes the sensitivity analysis.

Yoga Therapy: Building a Holding Environment for Somatic and Psyche Change.

Science.gov (United States)

McClure, Bud

2015-01-01

Drawing on ideas from D.W. Winnicott and the work of Quaker theologian Parker Palmer, this article discusses the concept of a holding environment, its refined understanding in the literature over the years, and how it can be optimally used in yoga therapy. The evidence shows that effectively establishing a holding environment can facilitate both somatic and deep structural change in a client, facilitating healing from primal wounding as well as the potential reconnection to the true self.

A Bright Promise but a Dim Future. Researchers Examine Potential of Educational Technology.

Science.gov (United States)

Pitts, Marcella R., Ed.

Concerns about the current educational technology movement are discussed in these four papers which were presented during a seminar of 20 representatives from 10 Council for Educational Development and Research (CEDaR) member institutions. The first by Marcella Pitts and E. Joseph Schneider provides an overview of the educational technology…

Fatigue Life of Stainless Steel in PWR Environments with Strain Holding

Energy Technology Data Exchange (ETDEWEB)

Kim, Taesoon; Kim, Kyuhyung [KHNP CRI, Daejeon (Korea, Republic of); Seo, Myeonggyu; Jang, Changheui [KAIST, Daejeon (Korea, Republic of)

2016-10-15

Many components and structures of nuclear power plants are exposed to the water chemistry conditions during the operation. Recently, as design life of nuclear power plant is expanded over 60 years, the environmentally assisted fatigue (EAF) due to these water chemistry conditions has been considered as one of the important damage mechanisms of the safety class 1 components. Therefore, many studies to evaluate the effect of light water reactor (LWR) coolant environments on fatigue life of materials have been conducted. Many EAF test results including Argonne National Laboratory’s consistently indicated the substantial reduction of fatigue life in the light water reactor environments. However, there is a discrepancy between laboratory test data and plant operating experience regarding the effects of environment on fatigue: while laboratory test data suggest huge accumulation of fatigue damage, very limited experience of cracking caused by the low cycle fatigue in light water reactor. These hold-time effect tests are preformed to characterize the effects of strain holding on the fatigue life of austenitic stainless steels in PWR environments in comparison with the existing fixed strain rate results. Low cycle fatigue life tests were conducted for the type 316 stainless steel in 310℃ air and PWR environments with triangular strain. In agreement with the previous reports, the LCF life was reduced in PWR environments. Also for the slower strain rate, the reduction of LCF life was greater than the faster strain rate. The LCF test conditions for the hold-time effects were determined by the references and consideration of actual plant transient. To simulate the heat-up and cooldown transient, sub-peak strain holding during the down-hill of strain amplitude was chosen instead of peak strain holding which used in the previous researches.

Current-day precision oncology: from cancer prevention, screening, drug development, and treatment - have we fallen short of the promise?

Science.gov (United States)

Morgan, Gilberto; Aftimos, Philippe; Awada, Ahmad

2016-09-01

Precision oncology has been a strategy of prevention, screening, and treatment. Although much has been invested, have the results fallen so far short of the promise? The advancement of technology and research has opened new doors, yet a variety of pitfalls are present. This review presents the successes, failures, and opportunities of precision oncology in the current landscape. The use of targeted gene sequencing and the overwhelming results of superresponders have generated much excitement and support for precision oncology from the medical community. Despite notable successes, many challenges still pave the way of precision oncology: intratumoral heterogeneity, the need for serial biopsies, availability of treatments, target prioritization, ethical issues with germline incidental findings, medical education, clinical trial design, and costs. Precision oncology shows much potential through the use of next-generation sequencing and molecular advances, but does this potential warrant the investment? There are many obstacles on the way of this technology that should make us question if the investment (both monetary and man-hours) will live up to the promise. The review aims to not criticize this technology, but to give a realistic view of where we are, especially regarding cancer treatment and prevention.

75 FR 35030 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2010-06-21

... outstanding shares of Paragon Commercial Corporation, and its subsidiary, Paragon Commercial Bank, both of... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company...

12 CFR 225.21 - Prohibited nonbanking activities and acquisitions; exempt bank holding companies.

Science.gov (United States)

2010-01-01

... CONTROL (REGULATION Y) Regulations Nonbanking Activities and Acquisitions by Bank Holding Companies § 225... company or a subsidiary may not engage in, or acquire or control, directly or indirectly, voting... Internal Revenue Code (26 U.S.C. 501(c)). (3) Companies granted hardship exemption. Any bank holding...

The Ins and Outs of Breath Holding: Simple Demonstrations of Complex Respiratory Physiology

Science.gov (United States)

Skow, Rachel J.; Day, Trevor A.; Fuller, Jonathan E.; Bruce, Christina D.; Steinback, Craig D.

2015-01-01

The physiology of breath holding is complex, and voluntary breath-hold duration is affected by many factors, including practice, psychology, respiratory chemoreflexes, and lung stretch. In this activity, we outline a number of simple laboratory activities or classroom demonstrations that illustrate the complexity of the integrative physiology…

75 FR 37804 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2010-06-30

... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The...: 1. Woori Finance Holdings Co., Ltd, Seoul, Korea; to acquire at least 51 percent of the voting shares of Hanmi Financial Corp., Los Angeles, California, and thereby indirectly acquire Hanmi Bank, Los...

75 FR 13763 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2010-03-23

... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The..., California 94105-1579: 1. North Asia Investment Corporation, Seoul, Korea; to become a bank holding company by acquiring 100 percent of the voting shares of Pacific City Financial Corporation, and Pacific City...

78 FR 41063 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2013-07-09

... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company... acquisition of a nonbanking company, the review also includes whether the acquisition of the nonbanking...

77 FR 69454 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2012-11-19

... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company... acquisition of a nonbanking company, the review also includes whether the acquisition of the nonbanking...

77 FR 42312 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2012-07-18

... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company... acquisition of a nonbanking company, the review also includes whether the acquisition of the nonbanking...

14 CFR 11.51 - May I request that FAA hold a public meeting on a rulemaking action?

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false May I request that FAA hold a public... Meetings and Other Proceedings § 11.51 May I request that FAA hold a public meeting on a rulemaking action? Yes, you may request that we hold a public meeting. FAA holds a public meeting when we need more than...

Multiple behavior changes in diet and activity: a randomized controlled trial using mobile technology.

Science.gov (United States)

Spring, Bonnie; Schneider, Kristin; McFadden, H Gene; Vaughn, Jocelyn; Kozak, Andrea T; Smith, Malaina; Moller, Arlen C; Epstein, Leonard H; Demott, Andrew; Hedeker, Donald; Siddique, Juned; Lloyd-Jones, Donald M

2012-05-28

Many patients exhibit multiple chronic disease risk behaviors. Research provides little information about advice that can maximize simultaneous health behavior changes. To test which combination of diet and activity advice maximizes healthy change, we randomized 204 adults with elevated saturated fat and low fruit and vegetable intake, high sedentary leisure time, and low physical activity to 1 of 4 treatments: increase fruit/vegetable intake and physical activity, decrease fat and sedentary leisure, decrease fat and increase physical activity, and increase fruit/vegetable intake and decrease sedentary leisure. Treatments provided 3 weeks of remote coaching supported by mobile decision support technology and financial incentives. During treatment, incentives were contingent on using the mobile device to self-monitor and attain behavioral targets; during follow-up, incentives were contingent only on recording. The outcome was standardized, composite improvement on the 4 diet and activity behaviors at the end of treatment and at 5-month follow-up. Of the 204 individuals randomized, 200 (98.0%) completed follow-up. The increase fruits/vegetables and decrease sedentary leisure treatments improved more than the other 3 treatments (P improved less than the other 3 treatments (P mobile technology and financial incentives holds promise to improve diet and activity. Targeting fruits/vegetables and sedentary leisure together maximizes overall adoption and maintenance of multiple healthy behavior changes.

Formal specification of a query expression generator using RSL ...

African Journals Online (AJOL)

From the specification, an implementation of our generator is generated in C++ using a command within the RSL project support environment that translates RSL to C++. The preliminary results with our generator show that it holds promise as a stand-alone tool as well. (Botswana Journal of Technology: 2002 11(2): 9-17) ...

Learning and Teaching with Mobile Devices an Approach in Secondary Education in Ghana

Science.gov (United States)

Grimus, Margarete; Ebner, Martin

2014-01-01

While many developing nations find Internet-based e-learning unsuitable for their needs (lack of technology as well as of accessibility), mobile learning methods--specifically those involving the use of mobile-phones for both formal and informal learning--hold great promise for them (Grimus et al, 2013b). This article examines the chances and…

Influence of the hold period on the fuel rod behaviour during a power ramp

International Nuclear Information System (INIS)

Bourreau, S.; Lansiart, S.; Couffin, P.; Verdeau, C.; Decroix, G.M.; Grandjean, M.-C.; Hugot, H.; Mermaz, F.; Van Schel, E.

2000-01-01

This paper presents three examples of power ramp tests performed in the OSIRIS experimental reactor, located at Saclay (France). The rods tested during these experiments stem from the same segmented 'mother' rod, pre-irradiated for two cycles in a French PWR. They underwent very similar power transient conditions, except for the hold time at Ramp Terminal Level (RTL) - respectively 41.5 kW/m (J12/2), 40.7 kW/m (J12/4) and 39.5 kW/m (J12/5) for RTL, but zero (J12/2), 16 minutes (J12/4) and 12 hours (J12/5) for the hold time at RTL. No failure was detected for any of the three experiments despite the relatively high mechanical stress applied to the cladding in the case of J12/2. Moreover, although no hold time was maintained at RTL, a permanent deformation clearly appeared on the clad during the power transient. An analysis of the cladding deformation has also been undertaken concerning the J12/2, J12/4 and J12/5 experiments. This study was realized by carrying out post-calculations of the three experiments with a 2D fuel modelling code using the finite element method. The computations satisfactorily reproduce the influence of hold time on the cladding deformation during the power transients, especially for the J12/2 and J12/4 experiments with hold times enclosing the failure times experimentally observed for power ramp tests. For the hold time of 12 hours, the micrographic observations of the fuel, compared to the case of the 16 minutes hold time, support the hypothesis of weak but noticeable gaseous swelling. (author)

Accurate step-hold tracking of smoothly varying periodic and aperiodic probability.

Science.gov (United States)

Ricci, Matthew; Gallistel, Randy

2017-07-01

Subjects observing many samples from a Bernoulli distribution are able to perceive an estimate of the generating parameter. A question of fundamental importance is how the current percept-what we think the probability now is-depends on the sequence of observed samples. Answers to this question are strongly constrained by the manner in which the current percept changes in response to changes in the hidden parameter. Subjects do not update their percept trial-by-trial when the hidden probability undergoes unpredictable and unsignaled step changes; instead, they update it only intermittently in a step-hold pattern. It could be that the step-hold pattern is not essential to the perception of probability and is only an artifact of step changes in the hidden parameter. However, we now report that the step-hold pattern obtains even when the parameter varies slowly and smoothly. It obtains even when the smooth variation is periodic (sinusoidal) and perceived as such. We elaborate on a previously published theory that accounts for: (i) the quantitative properties of the step-hold update pattern; (ii) subjects' quick and accurate reporting of changes; (iii) subjects' second thoughts about previously reported changes; (iv) subjects' detection of higher-order structure in patterns of change. We also call attention to the challenges these results pose for trial-by-trial updating theories.

Role of the CSIR/WRC Sanitation Technology Demonstration Centre in creating awareness, sharing information and in decision-making regarding sanitation technologies

CSIR Research Space (South Africa)

Mema, V

2010-09-01

Full Text Available The CSIR and the Water Research Commission (WRC) have envisioned a Sanitation Technology Demonstration Centre to provide a cutting-edge environment for bringing to light old and new, as well as promising sanitation technologies. The purpose...

The effects of breath-holding on pulmonary regurgitation measured by cardiovascular magnetic resonance velocity mapping

Directory of Open Access Journals (Sweden)

Babu-Narayan Sonya V

2009-01-01

Full Text Available Abstract Background Pulmonary regurgitation is a common and clinically important residual lesion after repair of tetralogy of Fallot. Cardiovascular magnetic resonance (CMR phase contrast velocity mapping is widely used for measurement of pulmonary regurgitant fraction. Breath-hold acquisitions, usually acquired during held expiration, are more convenient than the non-breath-hold approach, but we hypothesized that breath-holding might affect the amount of pulmonary regurgitation. Methods Forty-three adult patients with a previous repair of tetralogy of Fallot and residual pulmonary regurgitation were investigated with CMR. In each, pulmonary regurgitant fraction was measured from velocity maps transecting the pulmonary trunk, acquired during held expiration, held inspiration, by non-breath-hold acquisition, and also from the difference of right and left ventricular stroke volume measurements. Results Pulmonary regurgitant fraction was lower when measured by velocity mapping in held expiration compared with held inspiration, non-breath-hold or stroke volume difference (30.8 vs. 37.0, 35.6, 35.4%, p = 0.00017, 0.0035, 0.026. The regurgitant volume was lower in held expiration than in held inspiration (41.9 vs. 48.3, p = 0.0018. Pulmonary forward flow volume was larger during held expiration than during non-breath-hold (132 vs. 124 ml, p = 0.0024. Conclusion Pulmonary regurgitant fraction was significantly lower in held expiration compared with held inspiration, free breathing and stroke volume difference. Altered airway pressure could be a contributory factor. This information is relevant if breath-hold acquisition is to be substituted for non-breath-hold in the investigation of patients with a view to re-intervention.

76 FR 31680 - General Reporting and Recordkeeping by Savings Associations and Savings and Loan Holding Companies

Science.gov (United States)

2011-06-01

... Savings Associations and Savings and Loan Holding Companies AGENCY: Office of Thrift Supervision (OTS... Savings and Loan Holding Companies. OMB Number: 1550-0011. Form Number: N/A. Description: This information...), 12 CFR 562.4 (audit of savings association, savings and loan holding company, or affiliate), 12 CFR...

Effective Assistive Technology Consideration and Implications for Diverse Students

Science.gov (United States)

Jones, Vita L.; Hinesmon-Matthews, Lezlee J.

2014-01-01

Often the consideration of assistive technology devices and services during the individualized education program (IEP) process is overlooked. Because the Individuals with Disabilities Education Act (IDEA) authorized this consideration, IEP team members must be keenly aware of the importance they hold in providing this valuable input. Thus, IEP…

Impact of Information Technology Governance Structures on Strategic Alignment

Science.gov (United States)

Gordon, Fitzroy R.

2013-01-01

This dissertation is a study of the relationship between Information Technology (IT) strategic alignment and IT governance structure within the organization. This dissertation replicates Asante (2010) among a different population where the prior results continue to hold, the non-experimental approach explored two research questions but include two…

Sample-hold and analog multiplexer for multidetector systems

Energy Technology Data Exchange (ETDEWEB)

Goswami, G C; Ghoshdostidar, M R; Ghosh, B; Chaudhuri, N [North Bengal Univ., Darjeeling (India). Dept. of Physics

1982-08-15

A new sample-hold circuit with an analog multiplexer system is described. Designed for multichannel acquistion of data from an air shower array, the system is being used for accurate measurements of pulse heights from 16 channels by the use of a single ADC.

78 FR 57154 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2013-09-17

..., Maryland, to a state chartered commercial bank. B. Federal Reserve Bank of Dallas (E. Ann Worthy, Vice... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company...

76 FR 63923 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2011-10-14

... Security Bank of Washington, Mountlake Terrace, Washington, from a state savings bank to a commercial bank... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company...

78 FR 17206 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2013-03-20

... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company... involves the acquisition of a nonbanking company, the review also includes whether the acquisition of the...

75 FR 30405 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2010-06-01

... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company... involves the acquisition of a nonbanking company, the review also includes whether the acquisition of the...

78 FR 37222 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2013-06-20

... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company... involves the acquisition of a nonbanking company, the review also includes whether the acquisition of the...

78 FR 7430 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2013-02-01

... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company... involves the acquisition of a nonbanking company, the review also includes whether the acquisition of the...

77 FR 38816 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2012-06-29

... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company... involves the acquisition of a nonbanking company, the review also includes whether the acquisition of the...

77 FR 64993 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2012-10-24

... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company... involves the acquisition of a nonbanking company, the review also includes whether the acquisition of the...

77 FR 48156 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2012-08-13

... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company... involves the acquisition of a nonbanking company, the review also includes whether the acquisition of the...

75 FR 26961 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2010-05-13

... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company... involves the acquisition of a nonbanking company, the review also includes whether the acquisition of the...

75 FR 11888 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2010-03-12

... acquiring 87.31 percent of the voting shares of People's Bank of Seneca, Seneca, Missouri. B. Federal... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company...

76 FR 16477 - General Reporting and Recordkeeping by Savings Associations and Savings and Loan Holding Companies

Science.gov (United States)

2011-03-23

... Savings Associations and Savings and Loan Holding Companies AGENCY: Office of Thrift Supervision (OTS...), 12 CFR 562.4 (audit of savings association, savings and loan holding company, or affiliate), 12 CFR... the savings association), 12 CFR 584.1(f) (books and records of each savings and loan holding company...

Promise Zones for Applicants

Data.gov (United States)

Department of Housing and Urban Development — This tool assists applicants to HUD's Promise Zone initiative prepare data to submit with their application by allowing applicants to draw the exact location of the...

Using TV white space spectrum to practise telemedicine: A promising technology to enhance broadband internet connectivity within healthcare facilities in rural regions of developing countries.

Science.gov (United States)

Chavez, Afton; Littman-Quinn, Ryan; Ndlovu, Kagiso; Kovarik, Carrie L

2016-06-01

The following correspondence provides an overview of TV White Space (TVWS) technology, regulations, and potential applications to the health care sector. This report also introduces "Project Kgolagano," a Botswana-based initiative representing the first endeavour to utilize TVWS internet connection for practising telemedicine. TV "white space" refers to the previously unused, wasted spectrum within TV radiofrequency channels that can now be leveraged to obtain broadband internet access. TVWS represents a less costly, faster, and farther-reaching internet connection that is a promising option for connecting the previously unconnected populations of remote and underserved areas. The Botswana-University of Pennsylvania Partnership, Microsoft, Botswana Innovation Hub, Vista Life Sciences, and Global Broadband Solutions have partnered together to bring TVWS wireless broadband access to healthcare facilities in poorly connected regions of Botswana (Lobatse, Francistown, Maun, Gaborone) in order to improve healthcare delivery and facilitate telemedicine in dermatology, cervical cancer screening, and family medicine (HIV/AIDS, TB, general adult and pediatric medicine). © The Author(s) 2015.

Magnetic Resonance Imaging in Breath-Hold Divers with Cerebral Decompression Sickness

Directory of Open Access Journals (Sweden)

Ryu Matsuo

2014-01-01

Full Text Available The mechanism of cerebral decompression sickness (DCS is still unclear. We report 2 cases of breath-hold divers with cerebral DCS in whom magnetic resonance imaging (MRI demonstrated distinctive characteristics. One case presented right hemiparesthesia, diplopia, and gait disturbance after breath-hold diving into the sea at a depth of 20 m. Brain MRI with fluid-attenuated inversion recovery (FLAIR sequence revealed multiple hyperintense lesions in the right frontal lobe, bilateral thalamus, pons, and right cerebellar hemisphere. The second case presented visual and gait disturbance after repetitive breath-hold diving into the sea. FLAIR imaging showed hyperintense areas in the bilateral occipito-parietal lobes. In both cases, diffusion-weighted imaging and apparent diffusion coefficient mapping revealed hyperintense areas in the lesions identified by FLAIR. Moreover, follow-up MRI showed attenuation of the FLAIR signal abnormalities. These findings are suggestive of transient hyperpermeability in the microvasculature as a possible cause of cerebral DCS.

Life time calculations for LCF loading combined with tensional hold periods

International Nuclear Information System (INIS)

Bocek, M.; Armas, A.; Piel, D.

1983-01-01

The life time in high amplitude strain cycling with tensional hold periods is analysed presuming that creep failure damage is life determining. The life fraction rule (LFR) is used to calculate the life time consumpted during the dwell period in strain controlled tests as well as during tensional hold time stress cycles. It follows from the present investigation that stress relaxation occurring during the strain hold periods plays the dominant influence upon the relationship between life and dwell time. For strong stress relaxation (e.g. high temperature) less damage is accumulated as compared to suppressed relaxation (low temperature). The damage in stress relaxation is calculated by means of the LFR and the results are compared to experiments conducted on Zircaloy-4 and the austenitic stainless stell Type AISI 304. From the very good agreement between both it is concluded that under the loading conditions considered, creep failure damage is the main life determining damage contribution. (orig.)

A Progressive Approach to Integrating Education Technology

Science.gov (United States)

Nemcek, Felicia

2013-01-01

Do you ever have the feeling that with rapidly changing technology your students are driving the bus and you are holding on for dear life? According to the author, who is the principal of the Southwest Career and Technical Academy (SWCTA) located in Las Vegas, Nevada, they feel that way more often than not. However, she and her faculty understand…

New electric technologies to reduce global warming impacts

International Nuclear Information System (INIS)

Courtright, H.A.

1994-01-01

Advanced electric technologies hold significant potential to reduce global warming impact through reduction of primary fuel needed to power end-use applications. These reductions can occur in two forms: (1) reduced kilowatt-hour usage and power plant emissions through efficiency improvements and technological enhancements of existing electrically-driven applications; (2) the development of new electric technologies to replace traditional fossil-fuel driven applications which can result in less overall primary energy consumption and lower overall emissions. Numerous new electric technologies are presently being developed by the Electric Power Research Institute. The technologies reviewed in this paper include: Microwave Fabric Dryer, Advanced Heat Pumps, Heat Pump Water Heater, Infrared Sand Reclaimer, Freeze Concentration, Membrane Water Recovery, Microwave Petrochemical Production, Infrared Drying, and Electric Vehicles. Full commercialization of these technologies can result in significant energy savings and CO 2 reductions, in addition to improving the competitiveness of businesses using these technologies

75 FR 13129 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2010-03-18

... acquiring 100 percent of Circle Bank upon conversion of the bank from an industrial bank to a commercial... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company...

76 FR 67190 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2011-10-31

... Bank, Dover, Ohio, a thrift, upon its conversion to a national bank. B. Federal Reserve Bank of Atlanta... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The companies listed in this notice have applied to the Board for approval, pursuant to the Bank Holding Company...

77 FR 48983 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Science.gov (United States)

2012-08-15

..., Vice President) 33 Liberty Street, New York, New York 10045-0001: 1. Hana Financial Group Inc., Seoul, Korea; to become a bank holding company by acquiring 71.37 percent of the voting shares of BNB Financial... FEDERAL RESERVE SYSTEM Formations of, Acquisitions by, and Mergers of Bank Holding Companies The...

Acquisition Modernization: Transitioning Technology Into Warfighter Capability

Science.gov (United States)

2011-08-01

to test and evaluate the technology and integrate the new capability into operational weapon systems (Figure 4). This funding model creates stove...misalignment between missions, TRLs, and the RDT&E funding model is a major 11 contributor to the valley of death. Technologies become obsolete on... funding model of the acquisition system. Create an individual budget account to fund the development of promising technologies. The Acquisition

77 FR 32881 - Supervised Securities Holding Company Registration

Science.gov (United States)

2012-06-04

...), The Report of Foreign Banking Organizations (FR Y-7), The Consolidated Financial Statements for Bank... Y-9ES), The Supplement to the Consolidated Financial Statements for Bank Holding Companies (FR Y-9CS... comprehensive consolidated supervision by a foreign regulator, a nonbank financial company supervised by the...