Sample records for tale henry james

  1. Henry James – Modern Theoretician of Narration

    Directory of Open Access Journals (Sweden)

    Alexandra - Denisa IGNA


    Full Text Available Henry James, properly named world writer, was one of the first modern novelists, with an exigent writing conscience. The American writer subverted the prejudgement of the omniscient author in favour of the narration which is centred on the characters’ point of view, thus modernising the novel before V. Woolf, Huxley, Thomas Mann, or in our case Camil Petrescu and G. Călinescu. Some bio-bibliographical information familiarises the reader with the life and work of this writer. The larger part of the article is dedicated to a case study of the novel with the metaphorical title: The Figure in the Carpet, where Henry James tries to illustrate in an artistic manner his conception regarding the profundity and ineffability of the literary creation. The conclusion which the author reaches, alternating the familiar plan of the relationship between a married couple with the esthetical plan, is that the relationship between writer and his work represents an act of fully intimacy, just like a ceremony that takes place in the wedding night

  2. James Henry Greathead en die Londense Moltrein

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    Laurence Wright


    Full Text Available Die artikel ondersoek die oorsprong en vroeë geskiedenis van die toestel genaamd die ‘Greathead Skild’, ‘n belangrike nuwigheid in Viktoriaanse ingenieurwetenskap, wat van deurslaggewende belang was in die konstruksie van die Londense Moltrein. Die doel is om die basis te ontleed waarop, baie jare later, ‘n Suid-Afrikaanse ingenieur wye openbare erkenning in die vorm van ‘n standbeeld vir die ‘ontwerp’ van die Skild geniet het. Uit die perspektief van kulturele studies beskou, hoe moet ons uitvinding verstaan, gegewe dat ander briljante ingenieurs ook betrokke was? Hierdie vraag word ontleed met die gebruik van die konsep ‘extelligence’ (Stewart and Cohen 1997, in samehang met ander kontemporêre en geskiedkundige weergawes, insluitend Greathead se eie rekord van sy prestasies in die verrigtinge van die Instituut van Siviele Ingenieurs en voorgelê in The City and South London Railway (1896, onder redaksie van James Forrest. Hierdie artikel is die eerste keer as referaat aangebied by die konferensie oor ‘Nuuthede en Innovasie in die Negentiende Eeu’ aan die Noordwes-Universiteit, Mei 2016.

  3. Ecrire et souffrir : L’inspiration partagée de Constance Fenimore Woolson et de Henry James Literature and Grief: Constance Fenimore Woolson and Henry James, A Common Inspiration

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    Jeannine Hayat


    Full Text Available Miss Grief is a story by Constance Fenimore Woolson, an American novelist who often wrote about the difficulty a woman had in becoming an artist — a writer or a painter — in the nineteenth century. This tale is a very strange text, a kind of anticipation of a meeting to come, in Italy, in 1880, between Woolson and Henry James, and a friendship which lasted until the former’s death in 1894. For thirteen years, both writers would share a common inspiration. Death itself could not break the links between the two authors, who were connected even when settled in different European countries. William James, who was a member of the American Society for Psychical Research, probably helped his brother Henry to communicate — or so it appears — in some way with Woolson, even after her fatal accident, or possible suicide, in Venice. Henry James probably had in mind Miss Grief, a story by his dead friend, before writing some of his books. Indeed, Woolson had been the first to develop the image of “the figure in the carpet,” which was later transformed by Henry James. Woolson was also the first to devise a plot which Henry James would later use as a canvas for his novel The Wings of the Dove. What is an author and what is authorship? It seems impossible to separate what is Woolson’s and what is Henry James’s in four works of fiction that are in fact to be read together : Miss Grief, The Figure in the Carpet, The Beast in the Jungle, The Wings of the Dove.

  4. 1787 and 1776: Patrick Henry, James Madison, and the Revolutionary Legitimacy of the Constitution. (United States)

    Banning, Lance


    Discusses Patrick Henry's and James Madison's opinions on how the U.S. Constitution should be constructed. Describes how Henry introduced a set of substantive objections which were shared by Antifederalists throughout the country and persuaded many Revolutionaries that the Constitution was essentially at odds with the principles of 1776. (BSR)

  5. Beyond the Historical Record? Henry James in “The Master at St. Bartholomew’s Hospital

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    Elena Ogliari


    Full Text Available The article analyses the short-story “The Master at St Bartholomew’s Hospital 1914–1916” by Joyce Carol Oates (2007 in the broader context of the Jamesian biofiction, a series of novels and tales featuring Henry James as their protagonist. The addition of the prefix “bio-” to “fiction” points out the hybrid nature of these texts, which are a melange of biography, autobiography, criticism and fiction. Oates’s story not only epitomizes this hybridity, but it also proves to be an exploration of the potentiality of this subgenre to penetrate the mystery surrounding James’s persona and saturate the lacunae in his biography by resorting to what David Lodge defined as “the novelist’s licence”. The short-story is yet another evidence of Oates’s fascination with the unsaid in James’s life and prose, because it revolves around the silence into which he sank at the outbreak of the Great War, when he did not write anything in his pocket diaries for three months. In an attempt to go beyond the limits of the historical record, Oates gives insights into the mind of the author by depicting a Henry James in crisis – nagged by doubts about his artistic legacy – in an atmosphere of uncertainty enhanced by a complex intertextual play. The result is ‘a Henry James’ slightly divergent from the historical one: thus, the tale advocates the inaccessibility of the private life of a real individual. Nonetheless, the acknowledgement of this limit spurs the celebration of fictional imagination.

  6. M. Pirgerou on D. Izzo and C. Martinez’s Revisionary Interventions into Henry James

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    Full Text Available Donatella Izzo and Carlo Martinez. Revisionary Interventions Into Henry James. Eds. Napoli, 2008. Revisionary Interventions into Henry James is a compilation of a series of papers presented at a colloquium which took place at Università Orientale in Naples, Italy, on October 27, 2006. In her introduction to the volume, Donatella Izzo acknowledges the “rather blatant plagiarism” (7 which lent the book its title.  The borrowing, of course, refers to Donald Pease’s landmark Revisionary Interve...

  7. The delusion of the Master: the last days of Henry James. (United States)

    Bartolomeo, Paolo


    The novelist Henry James shared with his brother William, the author of the Principles of Psychology, a deep interest in the ways in which personal identity is built through one's history and experiences. At the end of his life, Henry James suffered a vascular stroke in the right hemisphere and developed a striking identity delusion. He dictated in a perfectly clear and coherent manner two letters as if they were written by Napoleon Bonaparte. He also showed signs of reduplicative paramnesia. Negative symptoms resulting from right hemisphere damage may disrupt the feelings of "warmth and intimacy and immediacy" and the "resemblance among the parts of a continuum of feelings (especially bodily feelings)", which are the foundation of personal identity according to William James. On the other hand, a left hemisphere receiving inadequate input from the damaged right hemisphere may produce positive symptoms such as delusional, confabulatory narratives. Other fragments dictated during Henry James's final disease reveal some form of insight, if partial and disintegrated, into his condition. Thus, even when consciousness is impaired by brain damage, something of its deep nature may persist, as attested by the literary characteristics of the last fragments of the Master.

  8. Confronting empty spaces: between interpretation and experience in "The Turn of the Screw" by Henry James

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    Antonia Spinelli


    Full Text Available The Turn of the Screw by Henry James has inspired the most various critical debates for over a century. What is hidden in the folds of the story? What kind of impact does it have on the reader? Like a borderless nebula who attracts and reflects light from other stars, this novella is permeated by a vide fascinant, by a chaotic and disturbing matter “such stuff as dreams are made”. This feeling of absence and uncertainty, that characterizes the story, developed trough the contribution of readers and critics and it found a further still precious echo in The Innocents, a film directed by Jack Clayton in 1961.

  9. Teaching the “Grandsons of Balzac” a Lesson: Henry James in the 1890’s

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    Dennis F. TREDY


    Full Text Available Lyall H. Powers, in Henry James and the Naturalist Movement, dubs the period spanning from “The Art of Fiction” in 1884 to The Tragic Muse in 1890 Henry James’s “Naturalist Experiment”, and rightfully so (Powers 3. There is much evidence, in James’s own notebooks, that The Bostonians was influenced by Daudet’s L’Évangeliste, The Princess Casamassima by Turgeneff’s Virgin Soil, and The Tragic Muse by the narrative techniques of Maupassant (NB 47, Powers 91, NB 92, and Powers effectively show...

  10. ‘Two Minds With but a Single Thought’: W. T. Stead, Henry James, and the Zancig Controversy

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    Paul Horn


    Full Text Available In 1906, two writers of disparate repute watched, and then wrote about a series of notorious performances by the London telepathists Julius and Agnes Zancig.One was W. T. Stead, the pugnacious purveyor of New Journalism and hugely influential in shaping public opinion; the other was Henry James, the author of a great number of highbrow, complex, and ultimately poorly selling works of prose fiction.James wrote in a letter of his impression of ‘the 'reality 'of their performance’ in the face of accusations of fraud based on a supposed ‘very wonderfully elaborated code of signalling’ between the pair.A persuasive factor was the rumour, told to him by the actor and theatre manager John Hare at a party, that Stead had proved the Zancigs’ telepathic powers during private tests at his own home.Stead published his own defence of the Zancigs in the 'Review of Reviews',' 'covering in detail their performance at the Alhambra Music Hall, and, indeed, the tests that seem likely to have been the subject of the gossip heard by James.What is especially remarkable about Stead’s article is that its description of the physical reality of telepathy is strikingly reminiscent of the instances of wordless communication that occur between the sensitive protagonists who populate James’s 'fin-de-siècle' novels.The aim of my paper is to use Stead’s and James’s shared interest in the Zancigs as a starting point from which to explore how the two writers’ authorial voices, ostensibly so different to each other, become closely imbricated as they converge on the topic of thought transference.In this way, I hope to show that in addition to the operation of rumour among their social milieu, Stead and James were connected by their appreciation of a more occulted form of communication, which would help define their apparently distinct contributions to 'fin-de-siècle' culture.



    Mello, Luiza Larangeira da Silva


    Resumo Este artigo propõe uma análise comparativa entre textos de caráter autobiográfico do intelectual e político brasileiro Joaquim Nabuco e do escritor norte-americano Henry James, nos quais eles modelam suas subjetividades e confrontam-se com alguns dos problemas que mobilizaram boa parte dos intelectuais, na virada do século XIX para o XX. Tanto Minha formação (1900), de Nabuco, quanto The American scene (1907), de James, representam o sentimento a que Evaldo Cabral de Mello chama "o dil...

  12. 'A Speculative Idea': The Parallel Trajectories of Financial Speculation, Obstetrical Science, and Fiscal Management of Female Bodies in Henry James's Washington Square. (United States)

    Nixon, Kari


    This essay teases out the intimate connections between the scientific and fiscal realms in the context of American germ theory and obstetrics. By uncovering the economic and medical contexts of Henry James's Washington Square-set during the infancy of germ theory and the heyday of American obstetrics-this essay exposes a previously unexplored subtextual history of contagion in the text. Although this scientific history seems relegated to the novel's margins, understanding the changing scientific cosmologies and professional organizations in the context of the novel's setting and composition reveals that these tiny infectious particles and their vectors fundamentally shape the plot of the novel.

  13. “Cash Is Better than Tenure”: (DeConstructing the “Posthistorical University” in James Hynes’s Gothic Academic Satire The Lecturer’s Tale

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    Andreescu Raluca


    Full Text Available This article analyzes the manner in which James Hynes’s novel The Lecturer’s Tale (2001 can be read as a satire of what Bill Readings identified in his influential The University in Ruins (1996 as the “posthistorical university.” I argue that, in the contemporary context in which higher education establishments are becoming more like corporations and the idea of culture is replaced by the “discourse of excellence,” Hynes’s novel offers an insightful discussion of universities’ negotiation of the Scylla of the pursuit of profit and the Charybdis of self-absorbed literary theorizing and its association with political correctness, the exploitation of junior and non-tenured faculty, and the quest for academic stardom. At the same time, I discuss the way in which the Gothic elements that permeate the novel fittingly double and deepen the critique of contemporary educational establishments and professors.

  14. Reading the Unknown/Speaking the Unspoken—An Analogy between Henry James’ What Maisie Knew and the Oscar Wilde Trial: Did James Really Know What Maisie Knew?

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    Dr. Michael R. Catanzaro


    Full Text Available The explicit and implicit language in Henry James’ novel, What Maisie Knew, reveals that the act of censoring was not exclusive to writers, since moral attitudes affected every aspect of society; consequently, people developed a means of communication via looks, gestures, and intonation that gave significant meaning to ordinary words and phrases, if one was part of the group “in the know.” This coded means of communication resulted from the anxiety of being accused of immoral activity by the political and religious regulating mechanisms, especially in a volatile society where many feared the outcome of a nation that was changing so rapidly. It was a means of protection. When writers could not provide graphically specific language and details, they would manipulate words to create a desired effect that relied on the readers to draw on their personal knowledge and experiences to supply meaning to the text; therefore, the interpretation was affected by the relationship between the reader and the subject matter.  

  15. Reading the Unknown/Speaking the Unspoken—An Analogy between Henry James’ What Maisie Knew and the Oscar Wilde Trial: Did James Really Know What Maisie Knew?

    Directory of Open Access Journals (Sweden)

    Dr. Michael R. Catanzaro


    Full Text Available The explicit and implicit language in Henry James’ novel, What Maisie Knew, reveals that the act of censoring was not exclusive to writers, since moral attitudes affected every aspect of society; consequently, people developed a means of communication via looks, gestures, and intonation that gave significant meaning to ordinary words and phrases, if one was part of the group “in the know.” This coded means of communication resulted from the anxiety of being accused of immoral activity by the political and religious regulating mechanisms, especially in a volatile society where many feared the outcome of a nation that was changing so rapidly. It was a means of protection. When writers could not provide graphically specific language and details, they would manipulate words to create a desired effect that relied on the readers to draw on their personal knowledge and experiences to supply meaning to the text; therefore, the interpretation was affected by the relationship between the reader and the subject matter.

  16. Tall Tales of North America. (United States)

    Fresno City Unified School District, CA.

    Designed for use in junior high school language arts classes, this learning activity packet introduces students to North American folklore. Selected readings cover Indian tales, real folk heroes (Davy Crockett and John Henry), imaginary folk heroes (Paul Bunyan and Pecos Bill), Black folk stories (Brer Rabbit), and tales of Washington Irving. Each…

  17. Vanglateenistuse enesekaitsekoolitus / Henri Palm

    Index Scriptorium Estoniae

    Palm, Henri


    Vanglateenistus korraldab Tartus, Tallinnas ja Jõhvis enesekaitsekoolitusi gümnaasiumiõpilastele. Jakob Westholmi abiturient Henri Palm on osalenud treeningutel osalenud kolm aastat ning jagab kogemusi

  18. Interview with Henry Jenkins


    TWC Editor


    An interview with Henry Jenkins focussing on Transformative Works and Cultures (TWC), the Organization for Transformative Works (OTW), and Jenkins' academic research into fan and participatory cultures.

  19. James Gillies

    CERN Multimedia


    "Physicist James gillies is chief of communications at CERN (the European Organisation for Nuclear Research). Based in the Jura foothills, just outside Geneva, Gillies is part of a teamt hat will fire up CERN's Large Hadron Collierd (LHC) - the most complicated piece of scientific equipment ever built." (1/2 page)

  20. Totally James (United States)

    Owens, Tom


    This article presents an interview with James Howe, author of "The Misfits" and "Totally Joe". In this interview, Howe discusses tolerance, diversity and the parallels between his own life and his literature. Howe's four books in addition to "The Misfits" and "Totally Joe" and his list of recommended books with lesbian, gay, bisexual, transgender,…

  1. Obituary: Henry Emil Kandrup, 1955-2003 (United States)

    Merritt, David; Gottesman, Stephen T.


    Henry Emil Kandrup died on 18 October 2003 at his home in Gainesville Florida. Henry was a theoretical astrophysicist specializing in the application of chaotic dynamics to stellar systems. At the time of his death, Henry was a Professor at the University of Florida where he had taught for 13 years. Henry was born in Manhasset, New York on July 24, 1955 and spent most of his childhood in Great Neck. His parents, Jytte and Fred, were immigrants from Denmark where his father had worked as a silver smith. Henry was a precocious child, skipping both third and fifth grades. With the help of Sidney Spivack, a professor of sociology at Columbia University, his parents enrolled Henry in the Brooks Preparatory School in Andover, Massachusetts. After graduating at age 16, Henry enrolled at Cornell, transferring to Princeton the following year. Henry's parents adored their only child and worked hard to provide him with intellectual opportunities. Henry became an accomplished musician (organ, piano, French horn) and linguist (English, Danish, German) and was a passionate devotee of opera and ballet. Henry received his PhD in 1980 from the University of Chicago, where his thesis advisor was James Ipser. He taught at Oakland University in Michigan and Syracuse University in New York before coming to the University of Florida in 1990. Henry was sui generis. He shunned conventionality in his personal appearance and in his public demeanor, and always chose forthrightness and candor over polite silence. But to those of us who knew Henry well, his bluntness was a reflection of his intellectual consistency. Henry always said exactly what he thought, both in his published work and his public presentations, and never compromised himself for the sake of appearances. Nothing that he said or wrote was less than fully thought out. Henry's PhD thesis was entitled "Stochastic Problems in Stellar Dynamics," and most of his subsequent research was in this field. Motion in stellar systems can be

  2. Interview with Henry Jenkins

    Directory of Open Access Journals (Sweden)

    TWC Editor


    Full Text Available An interview with Henry Jenkins focussing on Transformative Works and Cultures (TWC, the Organization for Transformative Works (OTW, and Jenkins' academic research into fan and participatory cultures.

  3. Henry Ford Health Systems (United States)

    Henry Ford Health Systems evolved from a hospital into a system delivering care to 2.5 million patients and includes the Cancer Epidemiology, Prevention and Control Program, which focuses on epidemiologic and public health aspects of cancer.

  4. Henry Gray's Anatomy. (United States)

    Pearce, J M S


    Little is generally known of Henry Gray, the author of Gray's Anatomy, and even less of his colleague Henry Vandyke Carter, who played a vital role in the dissections and illustrations leading to the production of the first volume in 1859. This essay attempts to sketch briefly the salient, know aspects of these two men and their divergent careers. It traces succinctly the subsequent fate of the unique anatomy book that has influenced and instructed almost every student of medicine. (c) 2009 Wiley-Liss, Inc.


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    Eve Kosofsky Sedgwick


    Full Text Available Teniendo en cuenta los debates recientes sobre el performance, la deconstrucción y la teoría de los actos del habla en relación con la interpretación del género, Eve K. Sedgwick explora sus aciertos y límites para imaginar una performatividad "queer". La autora concluye que la performatividad queer es una estrategia para significar, ser y hacer que ubica lo queer no en el territorio del esencialismo identitario, sino en el impulso performativo hacia nuevas posiciones relacionales a la normatividad; una estrategia que ya ella explora de manera brillante en la propia escritura de este ensayo. La inclusión de este texto en el número que celebra los primeros cinco años de la revista Nómadas busca asociar estas reflexiones queer a la pregunta que lo anima: ¿Qué significa ser nómada hoy.

  6. Performatividad Queer. The art of the Novel de Henry James

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    Eve Kosofsky Sedgwick


    Full Text Available Teniendo en cuenta los debates recientes sobre el performance, la deconstrucción y la teoría de los actos del habla en relación con la interpretación del género, Eve K. Sedgwick explora sus aciertos y límites para imaginar una performatividad “queer”. La autora concluye que la performatividad queer es una estrategia para significar, ser y hacer que ubica lo queer no en el territorio del esencialismo identitario, sino en el impulso performativo hacia nuevas posiciones relacionales a la normatividad; una estrategia que ya ella explora de manera brillante en la propia escritura de este ensayo. La inclusión de este texto en el número que celebra los primeros cinco años de la revista Nómadas busca asociar estas reflexiones queer a la pregunta que lo anima: ¿Qué significa ser nómada hoy.

  7. Phrygian Tales

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    J. B. Rives


    Full Text Available A survey of the ancient references to "Phrygian tales" reveals two characteristics: Euhemerizing accounts of the origin of the gods, and allegorical explanations of nature; the label may reflect the Phrygians' reputation as the oldest of nations.

  8. A Tale within a Tale: Mise en Abyme Adaptations of the Twenty-first Century

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    Željka Flegar


    Full Text Available In accord with the promise made by Henry Jenkins that “old and new media will interact in ever more complex ways” (Convergence Culture 6, this research observes metamodern fairy tale adaptations of the twenty-first century in light of Christina Bacchilega’s construct of the fairy-tale web and Henry Jenkins’ theory of convergence culture and transmedia storytelling. The research will address the growing trend of embedding “wonder tale” collections within the context of a larger narrative as an artefact of significance, power, and material value. Although original tales with known authorship, these fairy tale adaptations are appended to the mythology and culture of the fantastic secondary worlds. Such texts tend to be parodic, subversive, and even carnivalesque (Bakhtin; Stephens, providing a commentary on the culture of their origin, as well as our own. By blending cultures, styles, and formats, mise en abyme wonder tales also result in the empowerment of specifically marginalised groups. Generally defined as spin-offs that are otherwise a part of a complex inter- and hypertextual web, these fairy tale collections constitute a metafictional body of knowledge and wisdom. In the digital era much focus is placed on multimodal, hypertextual, and transmedia narratives with a significant influence of fandom on the production of such literary works. The study will focus on the popular examples of such practice, J.K. Rowling’s Tales of Beedle the Bard (2007/2008 and Ransom Riggs’ Tales of the Peculiar (2016, in order to define mise en abyme fairy tale adaptations, as well as to discuss their cultural significance and function.


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    Željko Kaluđerović


    Full Text Available In this paper the author discusses the views and statements of the French football player Thierry Henry he gave after his illegal play during the playoff match between France and the Republic of Ireland to claim one of the final spots in the World Cup 2010 in South Africa. First, by controlling the ball with his hand before passing it on for the goal Henry has shown disregard for the constitutive rules of football. Then, by stating that he is "not a referee" he demonstrated that for some players rules are not inherent to football and that they can be relativized, given that for them winning is the goal of the highest ontological status. Furthermore, he has rejected the rules of sportsmanship, thus expressing his opinion that the opponents are just obstacles which have to be removed in order to achieve your goals. Henry's action has disrupted major moral values, such as justice, honesty, responsibility and beneficence. The rules of fair play have totally been ignored both in Henry's action and in the Football Association of France's unwillingness to comment on whether a replay should take place. They have ignored one of the basic principles stated in the "Declaration of the International Fair Play Committee", according to which, fair play is much more than playing to the rules of the game; it's about the attitude of the sportsperson. It's about respecting your opponent and preserving his or her physical and psychological integrity. Finally, the author believes that the rules, moral values and fair play in football are required for this game to become actually possible to play


    Directory of Open Access Journals (Sweden)

    Željko Kaluđerović


    Full Text Available In this paper the author discusses the views and statements of the French football player Thierry Henry he gave after his illegal play during the playoff match between France and the Republic of Ireland to claim one of the final spots in the World Cup 2010 in South Africa. First, by controlling the ball with his hand before passing it on for the goal Henry has shown disregard for the constitutive rules of football. Then, by stating that he is "not a referee" he demonstrated that for some players rules are not inherent to football and that they can be relativized, given that for them winning is the goal of the highest ontological status. Furthermore, he has rejected the rules of sportsmanship, thus expressing his opinion that the opponents are just obstacles which have to be removed in order to achieve your goals. Henry's action has disrupted major moral values, such as justice, honesty, responsibility and beneficence. The rules of fair play have totally been ignored both in Henry's action and in the Football Association of France's unwillingness to comment on whether a replay should take place. They have ignored one of the basic principles stated in the "Declaration of the International Fair Play Committee", according to which, fair play is much more than playing to the rules of the game; it's about the attitude of the sportsperson. It's about respecting your opponent and preserving his or her physical and psychological integrity. Finally, the author believes that the rules, moral values and fair play in football are required for this game to become actually possible to play.

  11. Extraordinary Tales

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 20; Issue 10. Extraordinary Tales: Parasites Hijacking the Minds of Hosts. Felix Bast. General Article Volume 20 Issue 10 October 2015 pp 893-902. Fulltext. Click here to view fulltext PDF. Permanent link:

  12. Henry Gray, plagiarist. (United States)

    Richardson, Ruth


    The first edition of Anatomy Descriptive and Surgical (1858) was greeted with accolades, but also provoked serious controversy concerning Henry Gray's failure to acknowledge the work of earlier anatomists. A review in the Medical Times (1859) accused Gray of intellectual theft. The journal took the unusual step of substantiating its indictment by publishing twenty parallel texts from Gray and from a pre-existing textbook, Quain's Anatomy. At the recent "Vesalius Continuum" conference in Zakynthos, Greece (2014) Professor Brion Benninger disputed the theft by announcing from the floor the results of a computer analysis of both texts, which he reported exonerated Gray by revealing no evidence of plagiarism. The analysis has not been forthcoming, however, despite requests. Here the historian of Gray's Anatomy supplements the argument set out in the Medical Times 150 years ago with data suggesting unwelcome personality traits in Henry Gray, and demonstrating the utility of others' work to his professional advancement. Fair dealing in the world of anatomy and indeed the genuineness of the lustre of medical fame are important matters, but whether quantitative evidence has anything to add to the discussion concerning Gray's probity can be assessed only if Benninger makes public his computer analysis. © 2015 Wiley Periodicals, Inc.

  13. How James Kept the Pace?; A Look into the Organic Unity of "Daisy Miller" (United States)

    Movaghati, Sina; Comcar, Milad


    Many Critics believe that Henry James has set the definitive standards of modern fiction writing. Undoubtedly his groundbreaking article "The Art of Fiction," which published for the first time in 1884, has a major contribution in developing the theories of fiction writing. The term Organic Unity has derived from a major Formalist…

  14. TALE: a tale of genome editing. (United States)

    Zhang, Mingjie; Wang, Feng; Li, Shifei; Wang, Yan; Bai, Yun; Xu, Xueqing


    Transcription activator-like effectors (TALEs), first identified in Xanthomonas bacteria, are naturally occurring or artificially designed proteins that modulate gene transcription. These proteins recognize and bind DNA sequences based on a variable numbers of tandem repeats. Each repeat is comprised of a set of ∼ 34 conserved amino acids; within this conserved domain, there are usually two amino acids that distinguish one TALE from another. Interestingly, TALEs have revealed a simple cipher for the one-to-one recognition of proteins for DNA bases. Synthetic TALEs have been used to successfully target genes in a variety of species, including humans. Depending on the type of functional domain that is fused to the TALE of interest, these proteins can have diverse biological effects. For example, after binding DNA, TALEs fused to transcriptional activation domains can function as robust transcription factors (TALE-TFs), while fused to restriction endonucleases (TALENs) can cut DNA. Targeted genome editing, in theory, is capable of modifying any endogenous gene sequence of interest; this can be performed in cells or organisms, and may be applied to clinical gene-based therapies in the future. With current technologies, highly accurate, specific, and reliable gene editing cannot be achieved. Thus, recognition and binding mechanisms governing TALE biology are currently hot research areas. In this review, we summarize the major advances in TALE technology over the past several years with a focus on the interaction between TALEs and DNA, TALE design and construction, potential applications for this technology, and unique characteristics that make TALEs superior to zinc finger endonucleases. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Henry David Thoreau's Spiritual World

    Institute of Scientific and Technical Information of China (English)



    Henry David Thoreau was wholeheartedly in love with nature and he devoted almost all his life time to observation, appreciation and study of nature. Thus he formed a deep understanding of nature. In 1845, Thoreau began a two-year and two-month residence at Walden Pond. His life was lonely but full of fragrance. He wanted to live meaningfully, confront the essential facts of life and live a simple life. Based on the review of the literature related to this topic, this paper aims to study Henry David Thoreau’s spiritual world, especially reflected in his famous book-Walden.

  16. Sibling fairy tales

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    Luisa Brunori


    Full Text Available The article offers a reflection on sibling relationships starting from fairy tales. Their archetypical meaning and educative value are particularly analyzed. A selection of fairy tales having sibling relationships as their central theme is discussed.

  17. Richard Halliburton's Bearded Tales (United States)

    Morris, Charles E., III


    Fusing the concept of "the beard" with the genre of the tall tale to theorize bearded tales deepens our understanding of closet eloquence, or rhetorical repertories of sexual passing in U.S. history. An examination of adventurer-writer-lecturer Richard Halliburton's sexual provenance and bestselling travel tale, "The Royal Road to Romance" (1925),…

  18. Telling tales. (United States)

    Denning, Stephen


    A carefully chosen story can help the leader of an organization translate an abstract concept into a meaningful mandate for employees. The key is to know which narrative strategies are right for what circumstances. Knowledge management expert Stephen Denning explains that, for optimal effect, form should follow function. Challenging one professional storyteller's view that more is better, Denning points out that it's not always desirable (or practical) to launch into an epic that's jam-packed with complex characters, cleverly placed plot points, an intricate rising action, and a neatly resolved denouement. True, if listeners have time and interest, a narrative-savvy leader can use a vividly rendered tale to promote communication between management and staff, for instance, or even to foster collaboration--especially when the story is emotionally moving. However, if the aim is to motivate people to act when they might not be inclined to do so, it's best to take an approach that's light on detail. Otherwise, the particulars can bog listeners down and prevent them from focusing on the message. Drawing on his experiences at the World Bank and observations made elsewhere, the author provides several dos and don'ts for organizational storytellers, along with examples of narratives that get results. The sidebar "A Storytelling Catalog" presents seven distinct types of stories, the situations in which they should be told, and tips on how to tell them. Many of these aren't even stories in the "well-told" sense--they run the rhetorical gamut from one-liners to full-blown speeches--but they succeed because they're tailored to fit the situation. So even though it's common in business to favor the analytical over the anecdotal, leaders with the strength to push past some initial skepticism about the enterprise of storytelling will find that the creative effort pays off.

  19. The Life of Henry Eyring

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 17; Issue 7. The Life of Henry Eyring - From Mines to Molecules. Deepika Janakiraman. General Article Volume 17 Issue 7 July 2012 pp 625-634. Fulltext. Click here to view fulltext PDF. Permanent link:

  20. Henry Taube and Coordination Chemistry (United States)

    dropdown arrow Site Map A-Z Index Menu Synopsis Henry Taube and Coordination Chemistry Resources with Professor of Chemistry, Emeritus, at Stanford University, received the 1983 Nobel Prize in Chemistry " there from 1940-41. "I became deeply interested in chemistry soon after I came to Berkeley,"

  1. Revisiting the TALE repeat. (United States)

    Deng, Dong; Yan, Chuangye; Wu, Jianping; Pan, Xiaojing; Yan, Nieng


    Transcription activator-like (TAL) effectors specifically bind to double stranded (ds) DNA through a central domain of tandem repeats. Each TAL effector (TALE) repeat comprises 33-35 amino acids and recognizes one specific DNA base through a highly variable residue at a fixed position in the repeat. Structural studies have revealed the molecular basis of DNA recognition by TALE repeats. Examination of the overall structure reveals that the basic building block of TALE protein, namely a helical hairpin, is one-helix shifted from the previously defined TALE motif. Here we wish to suggest a structure-based re-demarcation of the TALE repeat which starts with the residues that bind to the DNA backbone phosphate and concludes with the base-recognition hyper-variable residue. This new numbering system is consistent with the α-solenoid superfamily to which TALE belongs, and reflects the structural integrity of TAL effectors. In addition, it confers integral number of TALE repeats that matches the number of bound DNA bases. We then present fifteen crystal structures of engineered dHax3 variants in complex with target DNA molecules, which elucidate the structural basis for the recognition of bases adenine (A) and guanine (G) by reported or uncharacterized TALE codes. Finally, we analyzed the sequence-structure correlation of the amino acid residues within a TALE repeat. The structural analyses reported here may advance the mechanistic understanding of TALE proteins and facilitate the design of TALEN with improved affinity and specificity.

  2. Henry Morgenthau's voice in history. (United States)

    Steiner, Pamela


    Henry Morgenthau (1856-1946) distinguished himself as the U.S. Ambassador to the Ottoman Empire, 1913-1916, and as the chairman of the League of Nations Refugee Settlement Commission (RSC) for Greece, 1923-24. I describe aspects of his early life that shaped the man he became, his accomplishments in these two posts, and his feelings about himself over time. At the end I briefly describe his attitude toward a possible Jewish state in Palestine.

  3. James Watt's Leicester Walk


    Bell, Kathleen


    a poem in which James Watt, inventor of the separate condenser, walks through contemporary Leicester (his route is from Bonners Lane and alongside the canal, taking in the Statue of Liberty on its traffic island near Sage Road). It is derived from the exercise of taking a character for a walk,

  4. How James Wood Works (United States)

    Goldstein, Evan R., Comp.


    Reading through news-media clippings about James Wood, one might reasonably conclude that "pre-eminent critic" is his official job title. In fact, Wood is a staff writer for "The New Yorker" and a professor of the practice of literary criticism at Harvard University. But at a time when there is much hand-wringing about the death of the…

  5. Lost Opportunities: Rediscovering Fairy Tales (United States)

    Wipf, Joan Brogan; Da Ros-Voseles, Denise


    The power of fairy tales resonates with children around the world. Fairy tales connect children on an emotional level that can help guide them through the complexities of everyday life. The tales provide stories rich in cultural heritage and the human condition, stories that not only delight children but also instruct. Because fairy tales state…

  6. James Nasmyth, Engineer (United States)

    Nasmyth, James; Smiles, Samuel


    Preface; 1. My ancestry; 2. Alexander Nasmyth; 3. An artist's family; 4. My early years; 5. My school-days; 6. Mechanical beginnings; 7. Henry Maudsley, London; 8. Maudsley's private assistant; 9. Holiday in the manufacturing districts; 10. Begin business at Manchester; 11. Bridgewater Foundry - partnership; 12. Free trade in ability - the strike - death of my father; 13. My marriage - the steam hammer; 14. Travels in France and Italy; 15. Steam hammer pile driver; 16. Nuremberg - St. Petersburg - Dannemora; 17. More about Bridgewater Foundry - Woolwich Arsenal; 18. Astronomical pursuits; 19. More about astronomy; 20. Retirement from business; 21. Active leisure; Chronological list of inventions and contrivances; Sun-ray origin of the pyramids, and cuneiform character; Index.

  7. Entrevista a James Curran


    Curran, James; Figueiras, Rita; Ribeiro, Nelson


    James Curran é professor catedrático e diretor do Goldsmiths Leverhulme Media Research Centre. A sua investigação centra-se sobretudo na relação entre os media e a democracia, quer através do ângulo da história dos media, quer da economia política dos media, áreas sobre as quais publicou mais de duas dezenas de livros, como Media and Democracy, Power without Responsability (co-autoria de Jean Seaton) e Media and Society. Na sua obra mais recente, Misunderstanding the Internet (co-autoria de N...

  8. Tales of Accreditation Woe. (United States)

    Dickmeyer, Nathan


    Offers cautionary tales depicting how an "Enron mentality" infiltrated three universities and jeopardized their accreditation status. The schools were guilty, respectively, of bad bookkeeping, lack of strategy and stable leadership, and loss of academic integrity by selling degrees. (EV)

  9. Henrys Fork near Ashton, ID (YHEN) (United States)

    Department of the Interior — Henrys Fork near Ashton, Idaho (YHEN) Sample Collection: Samples were collected near the USGS stream gage 13046000 (Latitude 44°04'11", Longitude 111°30'38" NAD83)....

  10. An interview with James Briscoe. (United States)

    Brown, Katherine


    James Briscoe is a group leader at The Francis Crick Institute in London. His lab's research focusses on the developing vertebrate spinal cord, with a particular interest in how sonic hedgehog gradients, and the downstream signal transduction and transcriptional networks, regulate the development of this tissue. In September 2018, James will become the new Editor-in-Chief of Development. We met with James to discuss his career and research interests, the importance of interdisciplinary thinking in developmental biology, and his views on the current state and future opportunities in scientific publishing. © 2018. Published by The Company of Biologists Ltd.

  11. American Hyperbole: The Tall Tale. (United States)

    Pavonetti, Linda M.; Combs, Christine M.


    Discusses the historic derivation and the format and characteristics of traditional tall tales, and modern adaptations of these stories. Describes a selection of tall tales for modern young adult readers; notes titles and authors of original tall tales and those with female heroes. Discusses the enduring appeal of traditional and modern tall…

  12. Psychoanalysis through fairy tale


    Muhič, Aleksandra


    In my thesis I present the unconscious process of a man through a fairy tale analysis. All mankind represent a major part of the unconscious. The answers to the questions about the essential, existencialism, are obtained by this major quantity of the unconscious in every man. Through the symbolism of a fairy tale I present the way an individual has to walk to gain selfrealisation in life. Through fairytales a child in the process of his personality maturing step by step says goodb ye to...

  13. James Blunt matuselaulude edetabeli tipus

    Index Scriptorium Estoniae


    Bereavement Registeri andmetel Suurbritannias matustel tellitavate laulude edetabelis: James Blunt "Goodbye My Lover", Robbie Williams "Angels", Jennifer Warnes ja Bill Medley "I've Had the Time Of My Life", Elton John "Candle in the Wind", Righteous Brothers "Unchained Melody"

  14. Joseph Henry's Conception of Scientific Knowledge (United States)

    Theerman, Paul


    Joseph Henry, America's premier physicist and physics teacher in the mid-nineteenth century, had decided views of scientific knowledge. These were expressed in two ways. First of all, scientific knowledge led to moral betterment. Thus the study of science was a morally good thing. This was not only because it led to the contemplation of God's creation, which was a standard reason justifying the study of science dating from the Scientific Revolution and even earlier. More importantly, the study of science itself was a moral discipline, imparting to scientists the habits and virtues of truthfulness, respect for others, care and diligence, and the discernment of meaningful patterns from experience. The moral ideals of science were expressed most strongly in Henry's upholding the international "Republic of Science"; conversely, cheapening science was a sign of moral failure. Second, for Henry and his generation, science provided a path to sure truth, separate from falsehood of both the politics and the quackery that characterized mid-century public life. Henry promoted this in his championing of the Smithsonian Institution a scientific establishment, against the ideas of others who wanted to make it a literary establishment or a training school for teachers. For Henry, the Smithsonian's scientific reputation would be established by relying on careful peer review in its publications, and supporting established scientists to write authoritative popular works. The purpose of both these activities was to raise the profile of science in the United States and further establish science and the scientific method as a guide to public life.

  15. From Realist to “Avant-garde”: Henry James in France

    Directory of Open Access Journals (Sweden)

    Micéala SYMINGTON


    Full Text Available “Je crois que l’apparence des choses est toujours trompeuse mais qu’à la longue cette tromperie de l’apparence devient l’équivalent de leur vérité, leur vérité même, et que sans doute il n’y a que ce faux-semblant qui au jour le jour puisse supporter d’être vécu.”Catherine Bertram, in La Bête dans la jungle by Marguerite Duras, states from the beginning of the play the essential truth which John Marcher only understands after her death: that appearances are deceptive, but that this deception ...

  16. 16 tales of innovation

    DEFF Research Database (Denmark)

    16 Tales of Innovation are told by 16 leaders, who have completed the LAICS executive master program, a collaboration between Aarhus University and Copenhagen Business School. The book is based on their Master theses and illustrates how they have experimented with different innovation tools, models...

  17. Technology and Fairy Tales

    DEFF Research Database (Denmark)

    Nørgaard, Jørgen


    The Danish writer Hans Christian Andersen was born 200 years ago and lived in a time of enormous progress in technology and science. He was excited about this, but also worried about what they would do to humans and culture. This dilemma is expressed in some of Andersen's fairy tales, here...

  18. Kolmanda maailma raudteekunn / Henry Posner ; interv. Krister Kivi

    Index Scriptorium Estoniae

    Posner, Henry


    Raudteeärimees Henry Posner III, kes kuulub ka Eesti Raudtee omanikeringi, oma äritegevusest, sealhulgas investeeringutest Eestisse. Suhtumisest raudteeturu avamisse. Lisa: Henry Posner mängib rongidega maailma hämarates nurkades

  19. Robert Henry Thurston: Professionalism and Engineering Education (United States)

    Nienkamp, Paul


    Robert Henry Thurston is presented in this article. He provides one the most significant examples of professionalizing engineering through innovative education and promoting scientific education practices in the late nineteenth century. The son of a draftsmen and steam engine mechanic, Thurston spent his early years in Providence, Rhode Island.…

  20. Antoine-Henri Jomini: A Bibliographical Survey. (United States)

    Alger, John I.

    Although the writings of Antoine-Henri Jomini influenced military thought during the 19th and 20th centuries, the obscurity of their publishing history has led to misunderstandings of the development and substance of Jomini's thought. This review attempts to (1) point out the continuity of his thought on the conduct of war, and (2) provide an…

  1. Translating China : Henri Borel (1869-1933)

    NARCIS (Netherlands)

    Heijns, A.J.


    This thesis investigates how Dutch sinologist Henri Borel ‘translated’ China, by examining his renditions of Chinese literature and the writings about China that he produced over a period of forty years. Borel studied Hokkien Chinese at Leiden University and in Xiamen toward a career as Chinese

  2. Transcendentalism and Henry Barnard's "School Architecture" (United States)

    Rothfork, John


    Sketches the intellectual and sociological climate that led Henry Barnard to advocate Greek Revival architecture for school buildings, takes a look at why this style and its implicit values were popular in the era between 1820-1860, and examines a few of the plans in Barnard's "School Architecture" (1838-48). (Author/RK)

  3. The Ideas of Henry Jenkins and Libraries (United States)

    Anderson, Byron


    Henry Jenkins, director of the Comparative Media Studies Program at the Massachusetts Institute of Technology and keynote speaker at the 2007 American Library Association's "Gaming, Learning and Libraries Symposium" in Chicago is a visionary leader in the areas of new media and media convergence. In a white paper on digital media and learning…

  4. James Stevens / James Stevens ; interv. Tilman Baumgärtel

    Index Scriptorium Estoniae

    Stevens, James


    Inglise disainerist James Stevensist (sünd. 1962) ja tema tegevusest. J. Stevens 2000. a. Amsterdamis tehtud intervjuus koos Jon Bainsi ja Kim Bulliga 1995. a. Londonis avatud Interneti-agentuurist Obsolete, 1996-2000 tegutsenud Interneti-kohvikust Backspace, mittekommertsiaalse juhtmeteta nerworki rajamisest Londonis

  5. James Moir as Organic Chemist

    African Journals Online (AJOL)


    James Moir (1874–1929) played an important role in the field of chemistry in South ... into the colour of organic compounds and the relationship be- tween colour ...... theory put forward by E.R.Watson,34 the depth of colour, or the displacement .... cover-glass, such as used in microscopy, to photograph absorp- tion bands ...

  6. James B. Macdonald: A Bibliography. (United States)

    Brubaker, Dale L., Comp.; Brookbank, Gayle, Comp.


    Presents a bibliography of James B. Macdonald's writings and printed speeches arranged chronologically according to the educator's themes of inquiry. Macdonald's videotaped autobiography identifies four explorative stages: (1) Scientism, (2) person-centered humanism, (3) sociopolitical humanism, and (4) transcendentalism, signaling a need for…

  7. Contaminant Monitoring Strategy for Henrys Lake, Idaho

    Energy Technology Data Exchange (ETDEWEB)

    John S. Irving; R. P. Breckenridge


    Henrys Lake, located in southeastern Idaho, is a large, shallow lake (6,600 acres, {approx} 17.1 feet maximum depth) located at 6,472 feet elevation in Fremont Co., Idaho at the headwaters of the Henrys Fork of the Snake River. The upper watershed is comprised of high mountains of the Targhee National Forest and the lakeshore is surrounded by extensive flats and wetlands, which are mostly privately owned. The lake has been dammed since 1922, and the upper 12 feet of the lake waters are allocated for downriver use. Henrys Lake is a naturally productive lake supporting a nationally recognized ''Blue Ribbon'' trout fishery. There is concern that increasing housing development and cattle grazing may accelerate eutrophication and result in winter and early spring fish kills. There has not been a recent thorough assessment of lake water quality. However, the Department of Environmental Quality (DEQ) is currently conducting a study of water quality on Henrys Lake and tributary streams. Septic systems and lawn runoff from housing developments on the north, west, and southwest shores could potentially contribute to the nutrient enrichment of the lake. Many houses are on steep hillsides where runoff from lawns, driveways, etc. drain into wetland flats along the lake or directly into the lake. In addition, seepage from septic systems (drainfields) drain directly into the wetlands enter groundwater areas that seep into the lake. Cattle grazing along the lake margin, riparian areas, and uplands is likely accelerating erosion and nutrient enrichment. Also, cattle grazing along riparian areas likely adds to nutrient enrichment of the lake through subsurface flow and direct runoff. Stream bank and lakeshore erosion may also accelerate eutrophication by increasing the sedimentation of the lake. Approximately nine streams feed the lake (see map), but flows are often severely reduced or completely eliminated due to irrigation diversion. In addition, subsurface

  8. Henri Fayol and Zero Tolerance Policies




    Zero tolerance policies have been increasingly popular in both education and business. Henri Fayol was the one of the earliest and influential thinkers in modern management theory. He defined management as a body of knowledge and defined his 14 administrative principles. It is an interesting exercise to apply Fayol’s teachings to the theory of zero tolerance and attempt to determine what Fayol would think of this new management technique.

  9. Henry P. McKean Jr. selecta

    CERN Document Server

    Moerbeke, Pierre; Moll, Victor


    This volume presents a selection of papers by Henry P. McKean, which illustrate the various areas in mathematics in which he has made seminal contributions. Topics covered include probability theory, integrable systems, geometry and financial mathematics. Each paper represents a contribution by Prof. McKean, either alone or together with other researchers, that has had a profound influence in the respective area.

  10. Deconstructing Gender in Revised Feminist Fairy Tales (United States)

    Mcandrew, Linda


    Power relationships are a central premise in children's literature, especially traditional fairy tales and modern feminist fairy tales. This is seen in many fairy tales where the main female character is in some distress, her Prince Charming rescues her, and they live happily ever after. Modern feminist fairy tales are understood to be a forum…

  11. James Peacock, Understanding Paul Auster

    Directory of Open Access Journals (Sweden)

    Chrysavgi Papayianni


    Full Text Available Paul Auster’s impressive gamut of work continues to incite fascination and controversy. Indeed, his compelling storytelling style taken together with his mixing of crime fiction and absurdism has made his readers and critics vacillate between praise and condemnation. James Peacock’s Understanding Paul Auster, sheds new light to otherwise obscure aspects of Auster’s novels, films, and other works undermining in this way the negative criticism of the past and thus creating a new appreciation fo...

  12. Conference James F.Buckli

    CERN Multimedia



    L'association du personnel a le plaisir d'accueillir Mons. James F.Buckli, astronaute, né en 1947. Il a participé à la mission Space Lab D1 qui pour la première fois mettait 8 personnes sur orbite.L'ass.du pers. remercie aussi Gordon White(s) de la mission américaine d'avoir permis d'organiser cette conférence

  13. A Conversation with James Hannan


    Gilliland, Dennis; Ramamoorthi, R. V.


    Jim Hannan is a professor who has lived an interesting life and one whose fundamental research in repeated games was not fully appreciated until late in his career. During his service as a meteorologist in the Army in World War II, Jim played poker and made weather forecasts. It is curious that his later research included strategies for repeated play that apply to selecting the best forecaster. ¶ James Hannan was born in Holyoke, Massachusetts on September 14, 1922. He attended St. Jero...

  14. A Note on Child Neglect in American Victorianism: Henry James’ "The Pupil"

    Directory of Open Access Journals (Sweden)

    F. Gül KOÇSOY


    Full Text Available In this study, the theme of “neglected child” in Henry James’ “The Pupil” (1891 is explored. Morgan is a neglected child with unscrupulous parents who hold strictly on the Victorian values which reflect American cultural consciousness in the last decades of 19th century. Although he is a brilliant boy, the family does not love him; because he reminds them of their vulgarity. They neglect him physically and emotionally, seeing him as a burden. Although his tutor tries to keep the boy from the family’s corruption, he contributes to his death; he neglects his illness and deserts him when he is most needy. As an interpreter, James draws attention to the situation of children that are not working but being tutored at home. He criticizes this culture’s general attitude towards children. It is a disturbing social reality and he shows how that materialistic culture victimizes children in terms of neglectful parenting

  15. Intervjuu James Corneriga = Interview with James Corner / James Corner ; interv. Andres Sevtshuk

    Index Scriptorium Estoniae

    Corner, James


    Büroo Field Operations maastikuarhitekt ning Pennsylvania Ülikooli maastikuarhitektuuri osakonna juhataja James Corner oma büroost, maastikust kui "instrumendist", postindustriaalsete aladega seotud projektidest (New Yorgi High Line'i muutmine pargiks ja promenaadiks), tööst suuremahuliste maastikega (Fresh Kills'i soo, endise prügila muutmine pargialaks), maastikuarhitektuurist ja linnakujundusest (maastiku urbanism), õpetamise tähtsusest oma töös ja maastikuarhitektuuri ideede arendamisel. Bibl. lk. 24

  16. Tales of Tourism

    DEFF Research Database (Denmark)

    Smed, Karina Madsen


    " and the "others". The author discusses to which extent tourism discourse is global as the reception of it has been different depending on the context. Moreover, she reflects on the impact upon this global narrative that the new economic world order will have. The new and emergent economies lead to a flow......Tales of Tourism - Global Changes and tourism discourse by Karina Smed presents us with what has been the dominant discourse of tourism, i.e. a discourse which has had its roots in the West's economic and cultural hegemony and the problem of the formation of identity from the dichotomy "self...... of tourists in the opposite direction: from China, India and Russia to western countries and worldwide and this will probably change the concept of tourism and our idea of identities....

  17. Henri Tamm : algul küsiti mult kogu aeg autogrammi / Henri Tamm ; interv. Ada Kallam

    Index Scriptorium Estoniae

    Tamm, Henri


    Draamaseriaali "Kodu keset linna" lapsnäitleja. Lisaks kolleegid Henrist : M. Veinmann "Tekst on tal esimesena peas", K. Maibaum "Võrdväärne partner suurtele". Artikkel pealkirjaga "Henri Tamm : nüüd saan veidi puhkust" : Linnaleht nr. 22, 3. juuni 2005, A2-A3


    Directory of Open Access Journals (Sweden)

    Saul Engelbourg


    Full Text Available Born in Germany and descendant of a wealthy banking family, Henry C. Wallich emigrated to the United States like others of Jewish ancestry who fled during the 1930s. A professor of money and banking at Yale for two decades, Wallich capped his career as a Governor of the Federal Reserve. During the stagflation of the late 1960s, Wallich, a dissenter, tirelessly advocated tighter monetary policy to stem inflation. Always a scholar, Wallich published extensively; he also served as the Fed’s public spokesman. Owing to his Harvard doctorate and his eminence as an economist, Wallich knew everyone worth knowing in the economics profession.

  19. Henri Becquerel: the discovery of radioactivity

    International Nuclear Information System (INIS)

    Allisy, A.


    This paper recalls the history of the Becquerel family, the fascinating time of the discovery of radioactivity as well as some important related research published before the radium age. Henri Becquerel was the third in the line of a family of scientists which extended over more than a hundred years. Following in the footsteps of his father and grandfather gave him a thorough grounding in scientific research methods. Science at the turn of the century was very exciting, the discovery of X rays had just been announced and scientists everywhere were hoping to discover new phenomena. (author)

  20. Henry Fuseli’s Alternative Classicism

    Directory of Open Access Journals (Sweden)

    Martin Myrone


    Full Text Available The review considers Andrei Pop’s Antiquity, Theatre & The Painting of Henry Fuseli. This argues for the history painter and writer Fuseli as an exemplary ‘Neopagan’, a term coined by Pop to refer to the new sense of cultural pluralism and historical relativism which emerged in Europe after the discovery of the remains of Pompeii and Herculaneum in 1748. While this perspective offers a fresh view of the artist, relating him to the emergence of modernity, and illuminates some important aspects of his work, the reviewer also suggests that the monographic focus risks re-asserting a sense of Fuseli’s exceptionalism.

  1. James Joyce, music and memory


    Brown, Katie


    This thesis, James Joyce, Music and Memory, explores the connection between music and Irish cultural memory in Joyce’s works from Chamber Music to the “pure music” of Finnegans Wake. Overall, it shows that Joyce’s ongoing desire to emulate musical forms must be seen in light of Joyce’s wish to come to terms with Irish cultural history, as these are the driving forces that bring about his changes in style. TARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please cont...

  2. William James on a phenomenological psychology of immediate experience: the true foundation for a science of consciousness? (United States)

    Taylor, Eugene


    Throughout his career, William James defended personal consciousness. In his "Principles of Psychology" (1890), he declared that psychology is the scientific study of states of consciousness as such and that he intended to presume from the outset that the thinker was the thought. But while writing it, he had been investigating a dynamic psychology of the subconscious, which found a major place in his Gifford Lectures, published as "The Varieties of Religious Experience" in 1902. This was the clearest statement James was able to make before he died with regard to his developing tripartite metaphysics of pragmatism, pluralism and radical empiricism, which essentially asked "Is a science of consciousness actually possible?" James's lineage in this regard, was inherited from an intuitive psychology of character formation that had been cast within a context of spiritual self-realization by the Swedenborgians and Transcendentalists of New England. Chief among these was his father, Henry James, Sr., and his godfather, Ralph Waldo Emerson. However, james was forced to square these ideas with the more rigorous scientific dictates of his day, which have endured to the present. As such, his ideas remain alive and vibrant, particularly among those arguing for the fusion of phenomenology, embodiment and cognitive neuroscience in the renewed search for a science of consciousness.

  3. Henry VIII, McLeod syndrome and Jacquetta's curse. (United States)

    Stride, P; Lopes Floro, K


    The mental decline of King Henry VIII from being a jovial, charismatic and athletic young man into an increasingly paranoid, brutal tyrant in later life, ever more concerned at his lack of one or more male heirs, has attracted many medical diagnostic theories. Previous hypotheses have included diabetes, syphilis and hypothyroidism, among others. However, these inadequately explain Henry's failure to produce a male heir, despite multiple pairings. The latest postulated diagnoses for Henry are the coexistence of both Kell blood group antigenicity (possibly inherited from Jacquetta Woodville, Henry's maternal great grandmother) causing related impaired fertility, and McLeod syndrome, causing psychotic changes. As the mutated McLeod protein of the syndrome significantly reduces the expression, effectively inactivating the Kell antigen, we critically review this theory, examining in detail the pathophysiology of these conditions and assessing the genealogy of Henry VIII and its effect in subsequent generations.

  4. Stapp's quantum dualism: The James/Heisenberg model of consciousness

    International Nuclear Information System (INIS)

    Noyes, H.P.


    Henry Stapp attempts to resolve the Cartesian dilemma by introducing what the author would characterize as an ontological dualism between mind and matter. His model for mind comes from William James' description of conscious events and for matter from Werner Heisenberg's ontological model for quantum events (wave function collapse). His demonstration of the isomorphism between the two types of events is successful, but in the author's opinion fails to establish a monistic, scientific theory. The author traces Stapp's failure to his adamant rejection of arbitrariness, or 'randomness'. This makes it impossible for him (or for Bohr and Pauli before him) to understand the power of Darwin's explanation of biology, let along the triumphs of modern 'neo-Darwinism'. The author notes that the point at issue is a modern version of the unresolved opposition between Leucippus and Democritus on one side and Epicurus on the other. Stapp's views are contrasted with recent discussions of consciousness by two eminent biologists: Crick and Edelman. They locate the problem firmly in the context of natural selection on the surface of the earth. Their approaches provide a sound basis for further scientific work. The author briefly examines the connection between this scientific (rather than ontological) framework and the new fundamental theory based on bit-strings and the combinatorial hierarchy

  5. Doctors, disease and James Joyce. (United States)

    Kaplan, Robert M


    The Irish author James Joyce is regarded as the greatest modernist writer of his time. His works, notably The Dead, A Portrait of the Artist as a Young Man, Ulysses and Finnegans Wake--are intensely autobiographic including meticulous descriptions of illness and states of health--no surprise in view of Joyce's medical history and hypochondria. The Dead revolves around the tragic love of a doomed tubercular youth. Ulysses has a graphic description of Mary Joyce-s death, a funeral and a birth; Stephen Dedalus, the character based on Joyce, attends a drinking session with medical students at the lying-in hospital just as Joyce had done as a student; references to syphilis, alcoholism and other illnesses abound.

  6. Obituary: Henry Albers (1925-2009) (United States)

    Chromey, Fred


    Henry Albers, professor of astronomy at Vassar College for over thirty years, died March 29, 2009, in Fairhope, Alabama. For his work at Vassar, where he held the Maria Mitchell Chair, Albers received the first Maria Mitchell Women in Science Award for his inspiration of women astronomers. He said "In the final analysis it is the students who bring the joy into teaching." As a professional astronomer, Albers did observational work on Galactic structure in the southern Milky Way, and on the structure of the Magellanic Clouds. In retirement, Albers published Maria Mitchell - A Life in Journals and Letters, the firsthand account of America's first woman astronomer. Albers's research was on photographic near-infrared spectroscopy of red giant stars in the southern Milky Way, some proper motion studies, and on the structure of the Magellanic Clouds. A series of seven NSF grants supported his six trips to Chile to make spectroscopic observations, as well as his sabbatical collaborations at Minnesota, Leiden, and the Royal Observatory in Edinburgh. Henry Albers arrived at Vassar in 1958, to find an astronomy program that had been recently absorbed by the physics department, and that was suffering neglect after the retirement of Maud Makemson. For the next 31 years, with incredible energy -- he sometimes taught seven courses a year -- he built the astronomy program into one double in size (from one to two tenure lines), whose th century facilities have been replaced with a st century observatory. For a remarkable stretch of 20-some-years, Albers and physicist Bob Stearns, with considerable grace, alternated chairmanship of the joint department of physics and astronomy. Henry Albers was a devoted citizen of Vassar College and an enthusiastic participant in the process of faculty governance at that institution. He would have been the first to concede that his enthusiasm was sometimes excessive, and that his contributions at faculty meetings occasionally failed to move the

  7. The Scientific Papers of James Clerk Maxwell (United States)

    Clerk Maxwell, James; Niven, W. D.


    homogeneous quadratic functions; 57. On the focal lines of a refracted pencil; 58. An Essay on the mathematical principles of physics. By Rev. James Challis. (Review); 59. On Loschmidt's experiments on diffusion in relation to the kinetic theory of gases; 60. On the final state of a system of molecules in motion subject to forces of any kind; 61. Faraday; 62. Molecules (a lecture); 63. On double refraction in a viscous fluid in motion; 64. On Hamilton's characteristic function for a narrow beam of light; 65. On the relation of geometrical optics to other parts of mathematics and physics; 66. Plateau on soap-bubbles (Review); 67. Grove's Correlation of physical forces (Review); 68. On the application of Kirchhoff's rules for electric circuits to the solution of a geometric problem; 69. Van der Waals on the continuity of the gaseous and liquid states; 70. On the centre of motion of the eye; 71. On the dynamical evidence of the molecular constitution of bodies (a lecture); 72. On the application of Hamilton's characteristic function to the theory of an optical instrument symmetrical about its axis; 73. Atom; 74. Attraction; 75. On Bow's method of drawing diagrams in graphical statics with illustrations from Peaucellier's Linkage; 76. On the equilibrium of heterogeneous substances; 77. Diffusion of gases through absorbing substances; 78. General considerations concerning scientific apparatus; 79. Instruments connected with fluids; 80. Whewell's Writing and correspondence (Review); 81. On Ohm's Law; 82. On the protection of buildings from lightning; 83. Capillary action; 84. Hermann Ludwig Ferdinand Helmholtz; 85. On a paradox in the theory of attraction; 86. On approximate multiple integration between limits by summation; 87. On the unpublished electrical papers of the Hon. Henry Cavendish; 88. Constitution of bodies; 89. Diffusion; 90. Diagrams; 91. Tait's Thermo

  8. Contest in Nanai Shamanic Tales

    Directory of Open Access Journals (Sweden)

    Tatiana Diomidovna Bulgakova


    Full Text Available The tale motif of the shamanic tale competition is examined with due regard for the interpretation given by the Nanai storyteller-shamans from the standpoint of their personal spiritual experience. In shamanic practice it is not the personal ability (skill or physical power that provides a challenger victory in conflict, but obtaining spirits-helpers more powerful than those of his or her rival. The predominate role of these fantastic personages/helpers in tales that represent invisible spirit helpers perform real shamanic praxis, explains the loser’s unconditional submission and readiness to sacrifice their freedom or life to the winner. It also clarifies the motivation of the initiators of these contests and games: by means of gathering a great number of competitors, such shamans solve their personal spiritual problems, such as the need to overcome their adversaries or find allies in the struggle against their opponents.

  9. The TA and TALE Experiments

    International Nuclear Information System (INIS)

    Thomson, Gordon


    The TA/TALE experiment is under construction, and is being deployed in Millard County, Utah. It will consist of a suite of detectors covering four orders of magnitude in energy, from 10 16.5 to 10 20.5 eV, and will observe cosmic ray showers with fluorescence detectors and arrays of scintillation counters. Events will be seen by multiple detectors and cross calibration of detectors' energy scales will be possible. TA/TALE will observe all three features of the spectrum of ultrahigh energy cosmic rays, observe the galactic/extragalactic transition, study the cosmology of cosmic ray sources, and perform anisotropy studies with unprecedented accuracy

  10. Ladrillo and Tales of Juan Bobo: Puerto Rican Folk Tales. (United States)

    Matos, Reinaldo; Matos, Ana

    These two illustrated elementary readers contain the Spanish and English versions of the Puerto Rican folk tales, "Ladrillo" and "Cuentos de Juan Bobo." They are part of a series of reading materials for elementary-level migrant children. These materials are intended to help the child relate to his culture, develop interest in…


    White, Robert S


    In the analysis of a woman with multiple childhood traumas, the fairy tale "Hansel and Gretel" figured prominently. The author discusses the use of the fairy tale in this case at various levels. He suggests an interplay between a national myth, the fairy tale, and a personal myth-the patient's psychodynamics. The fairy tale can be used to illuminate personal meanings derived from it. In the experience of childhood trauma, the repeated reading of a fairy tale can help organize and defend against terrifying anxiety. © 2015 The Psychoanalytic Quarterly, Inc.

  12. James Stirling Regionalismo y modernidad

    Directory of Open Access Journals (Sweden)

    Javier de Esteban Garbayo


    Full Text Available ResumenEn los años treinta, la arquitectura moderna se había introducido en los más remotos lugares del mundo enfrentándose con la infinita idiosincrasia de lo local, y al mismo tiempo, el arquitecto, sintiendo las limitaciones de su estilo e intentando ampliar su vocabulario, se embarcó en un proceso de difusión, asimilación y personalización.La idea de una renovada época después de la posguerra británica, sería compartida por una joven generación de arquitectos con el fin de encontrar una nueva forma de modernidad.Si en sus proyectos domésticos de mediados de los cincuenta, James Stirling partió de una aproximación al regionalismo y a la 'tradición funcional' con el fin de renovar el lenguaje moderno, no abandonaría la idea 'programática' inicial de entender la arquitectura desde una consistencia formal y una lógica que combinaba 'una síntesis común del pasado reciente y una certera actitud hacia el futuro'. AbstractThirties, modern architecture had percolated into remote corners of the world, encountering the infinite idiosyncrasies of locality, and, at the same time, Architects, feelings the limitations of their style and becoming intent upon extending their vocabulary, embarked upon a process of diffusion, assimilation and personalitation.The idea of a renewed period after British postwar, was shared for a new young architects generationto find a new way of modernity.While in his mid fifties housing projects, James Stirling approached to 'regionalism' and 'the functional tradition' to renew the modern language, he wouldn't reject the programmatic idea to understand architecture from a logic and formal consistency that combine 'a common synthesis of the recent past and a certain attitude toward the future'.

  13. VoxHenry: FFT-Accelerated Inductance Extraction for Voxelized Geometries

    KAUST Repository

    Yucel, Abdulkadir C.; Georgakis, Ioannis P.; Polimeridis, Athanasios G.; Bagci, Hakan; White, Jacob K.


    inductance extractor, FastHenry. Just like FastHenry, VoxHenry solves a combination of the electric volume integral equation and the current continuity equation, but with three distinctions that make VoxHenry suitable and extremely efficient for analyzing

  14. Nationalism in James Joyce's Ulysses

    Directory of Open Access Journals (Sweden)

    Bahee Hadaegh


    Full Text Available In the present article, the role of nationalism and postcolonialism in James Joyce's Ulysses is explored. The novel is used to reveal the political and postcolonial layers of Joyce's work and represent how colonization works through politics. This helps the readers to realize more about political Joyce and to apprehend his political views as a fresh reading of his oeuvre. The significance of this article is to depict how an author from a colonized society is influenced by the colonizing forces and cultural invasions and to scrutinize the very psychology of a colonized nation. This task is done through Attridge and Howes's methodology as the theoretical framework containing key roles in analyzing the main discussion. Through analyzing Ulysses, this article clearly shows that Joyce was a part of nationalistic movements such as the Irish Revival; however he had major conflicts with some individuals and movements that claimed to be nationalists. Therefore, Joyce is concluded to be a 'semicolonial' writer who has his own specific mode of nationalism.

  15. A chat with James Watson

    CERN Multimedia


    On 6 September, Nobel laureate James Watson paid a visit to CERN. In this interview, he shares his views with CERN's Paola Catapano.      var flash_video_player=get_video_player_path(); insert_player_for_external('Video/Public/Movies/2011/CERN-MOVIE-2011-144/CERN-MOVIE-2011-144-0753-kbps-640x360-25-fps-audio-64-kbps-44-kHz-stereo', 'mms://', 'false', 480, 360, '', '1384418', true, 'Video/Public/Movies/2011/CERN-MOVIE-2011-144/CERN-MOVIE-2011-144-0600-kbps-maxH-360-25-fps-audio-128-kbps-48-kHz-stereo.mp4');

  16. NOAA Ship Henry B. Bigelow Underway Meteorological Data, Quality Controlled (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Henry B. Bigelow Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  17. Comparison of the acute effects of Tulbaghia violacea William Henry ...

    African Journals Online (AJOL)

    William Henry Harvey (Alliaceae) on blood pressure and heart rate of ... (WKY), and compare the results obtained with those for adult spontaneously hypertensive rats (SHR). Methods: T. ... have similar secondary metabolites and biological ...

  18. Henri Poincaré: Death centenary (1854-1912) (United States)

    Heinzmann, Gerhard; Villani, Cédric


    The year 2012 marked the centenary of the death of Henri Poincaré (Nancy, 1854-Paris, 1912), and through the agency of the Henri-Poincaré Institute in Paris, the Henri-Poincaré Archives in Nancy and The London Mathematical Society, brought with it several exhibitions and meetings commemorating one of the greatest minds in contemporary times. Often referred to as the last polymath, Poincaré embraced multiple branches of mathematics, theoretical physics and celestial mechanics, and made significant contributions to philosophy of science (Heinzmann & Stump, Henri Poincaré, 2013). He wrote 25 textbooks and monographs, 500-plus articles, and was deeply involved in the organization and administration of science at both the national and international levels.1

  19. Creative Thinking with Fairy Tales. (United States)

    Flack, Jerry


    This article discusses how creative thinking can be encouraged in students through such classic tools as brainstorming and the productive thinking elements of fluency, flexibility, originality, and elaboration. It describes how fairy tales can be used to foster these thinking skills and suggests classroom activities. (Contains two references.) (CR)

  20. Learning through a Winter's Tale (United States)

    Vidotto, Kristie


    In this article, the author shares her experience during the final semester of Year 11 Theatre Studies when she performed a monologue about Hermione from "The Winter's Tale". This experience was extremely significant to her because it nearly made her lose faith in one of the most important parts of her life, drama. She believes this…

  1. A Tale of Four Electrons (United States)

    Burgmayer, Paul


    "A Tale of Four Electrons" is a creative writing assignment used with 10th-grade Honors Chemistry students. The project helps students consolidate their learning about bonding--an important unifying theme in chemistry--and answers questions such as (1) How are ionic, metallic, and covalent bonds related? (2) How do variations in electron…

  2. [A tale of two encounters]. (United States)

    Chanel, Marie-Paule

    The moving testimony of a patient shows the impact which a successful encounter can have. Beyond the positive clinical consequences, her rediscovered motivation and pleasure are the essential drivers which have guided her along the pathway of reconstruction. A tale of two encounters which have marked her life course. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  3. L'Abbe Henri Breuil: Archaeologist

    Directory of Open Access Journals (Sweden)

    Lawrence Guy Straus


    Full Text Available In his otherwise excellent book, A History of Archaeological Thought, Trigger (1989: 156 makes only one passing reference in a half-sentence to the central figure in the development of Paleolithic prehistory in the first half of the 20th century -- and manages to get his name wrong, confusing Henri Breuil with his long-time, close colleague, Hugo Obenrnaie . Thirty years after his death, Breuil's role in the history of Old World prehistory required more serious consideration. He was a seminal figure not only in rock art studies, but also in the archaeology of at least France, Spain, England, Portugal, South Africa, and China. Before I had read Trigger's work or Sackett's (1991 critique of my supposed misinterpretation of Breuil's theoretical stance (e.g., Straus 1986, 1987, I had presented a review of Breuil's contributions in the 1991 Annual Snead-Wertheim Lecture in Anthropology and History at the University of New Mexico (Straus n.d.. The following is a brief summary of some of my conclusions.

  4. Henry Head and the Theatre of Reverie

    Directory of Open Access Journals (Sweden)

    Tiffany Watt-Smith


    Full Text Available In 1903, the neurologist Henry Head (1861-1940 embarked on a painful self-experiment, in which he severed the radial nerve of his left arm, and then charted the gradual and faltering return of sensitivity to the limb over the next four and a half years. To directly experience his own sensations, Head entered into a trance-like state of distraction or reverie he called a ‘negative attitude of attention’. This article explores Head’s peculiar technique for looking within, and argues that while introspection was an established strategy in psychological laboratories, Head’s reverie also resonated with techniques associated with actors and theatrical audiences during this period. Viewing psychological self-experimentation through the lens of theatre, this article makes visible aspects of Head’s embodied, affective laboratory encounters, often obscured in accounts of his experiment. At the same time, it proposes that the broader historical and cultural significance of Head’s experiment lies in his attempt to observe himself by producing states of inattention and reverie at will, mental ‘attitudes’ that were themselves the subject of a rapidly evolving debate in scientific and aesthetic circles at the turn of the twentieth century.

  5. Victor Henri: 111 years of his equation. (United States)

    Cornish-Bowden, Athel; Mazat, Jean-Pierre; Nicolas, Serge


    Victor Henri's great contribution to the understanding of enzyme kinetics and mechanism is not always given the credit that it deserves. In addition, his earlier work in experimental psychology is totally unknown to biochemists, and his later work in spectroscopy and photobiology almost equally so. Applying great rigour to his analysis he succeeded in obtaining a model of enzyme action that explained all of the observations available to him, and he showed why the considerable amount of work done in the preceding decade had not led to understanding. His view was that only physical chemistry could explain the behaviour of enzymes, and that models should be judged in accordance with their capacity not only to explain previously known facts but also to predict new observations against which they could be tested. The kinetic equation usually attributed to Michaelis and Menten was in reality due to him. His thesis of 1903 is now available in English. Copyright © 2014 Elsevier B.V. and Société française de biochimie et biologie Moléculaire (SFBBM). All rights reserved.

  6. Obituary: James Houck (1940 - 2015) (United States)

    Weedman, Daniel; Barry, Donald; Soifer, Thomas

    James R. Houck, the leading figure in developing infrared spectroscopy for astrophysics, died in Ithaca, NY, on September 18, 2015, at age 74 from complications of Alzheimer's Disease. He was born on October 5, 1940, in Mobile, Alabama, but lived much of his early life in Pittsburgh, Pennsylvania, where he received his undergraduate degree from Carnegie Institute of Technology. Jim spent his scientific career at Cornell University. He came to Cornell as a physics graduate student in 1962 and remained until his retirement as the Kenneth A. Wallace Professor of Astronomy in 2012. His only year away from Ithaca was as a Guggenheim Fellow at Caltech, and he declined job offers from other universities because of his opinion that Ithaca provided the best environment for raising his family. His passion for learning, doing, and teaching science by building instruments and understanding physics led to great benefits for his students and astronomy colleagues. After receiving his PhD in condensed matter physics, he changed fields to work in astronomy at Cornell. He first collaborated with colleague Martin Harwit to develop a rocket program at Cornell for infrared observations and made numerous treks to the White Sands Missile Range flying payloads on Aerobee sounding rockets. Jim emphasized building spectrographs and making pioneering observations with ground based, airborne, and rocket-borne infrared instrumentation. Jim flew on every airplane NASA provided for astronomy. Those were pioneering times. One of his survival stories was of the Learjet in which both engines flamed out over the Pacific when the pilot did a celebratory barrel role after successful completion of their observations. His observations with rockets and airplanes were primarily of a variety of Galactic objects, including planetary nebulae, HII regions, and stars. But the most notable was an observation on the Convair 990 that produced a prescient discovery paper in 1973 led by Jim which discovered bound

  7. St. James marine terminal facility description

    Energy Technology Data Exchange (ETDEWEB)


    The US Department of Energy (DOE) currently owns and operates a marine terminal on the west bank of the Mississippi River at St. James, Louisiana. The St. James facility was constructed by the Department to provide marine services associated with the fill and drawdown of the Strategic Petroleum Reserve (SPR) crude oil storage facilities located at Bayou Choctaw and Weeks Island, Louisiana. Although strategic to the mission of the SPR in the event of a national emergency, the St. James terminal is situated such that it has a high potential to also serve the commercial industry`s needs for crude oil terminalling and storage. The St. James terminal is located approximately 45 miles west of New Orleans and 30 miles southeast of Baton Rouge, and approximately 160 miles upstream from the mouth of the Mississippi River. Construction of the St. James terminal was initiated in 1978 and was completed in 1980. Since then, the terminal has received and transferred over 125 million barrels of crude oil to the SPR sites for storage. For crude oil distribution, the St. James terminal was connected to the neighboring LOCAP terminal by a 0.1 mile 36-inch pipeline in 1981 and to the Capline terminal by a 0.5 mile 30-inch pipeline in 1988. The terminal also has a 30-inch pipeline connection to the Koch oil terminal which was used for initial fill purposes; however, this pipeline has been disconnected and is currently inactive. A complete description of the St. James terminal facilities, operational capabilities, operational certifications, and future Government requirements are presented in Sections 2, 3, 4, and 5 respectively.

  8. The Treachery in Teaching Henry James, Hayim Nachman Bialik, Walter Benjamin, and Nachman of Bratzlav's Tradition of Translation. (United States)

    Cutter, William


    Views teaching as a form of translation. Discusses the prospects of precise teaching and sets forth some thoughts concerning an ideal model. Delineates discussion from the literary, mystical, and philosophical dimensions in order to elucidate the instructional tasks of religious education. Points out the paradoxes of teaching. (KO)

  9. Poor and Rich in James: A Relevance Theory Approach to James's Use of the Old Testament (United States)

    Morales, Nelson R.


    The epistle of James was for years a forgotten book in academic circles. In recent decades, however, a renewed focus on early Judaism has generated interest in looking at James with new eyes. Poverty and wealth in the epistle continues to be a point of interest. Other topics, however, are still to be explored. One of these topics is the rhetorical…

  10. “Not a man from England”: assimilating the exotic ‘other’ through performance, from Henry IV to Henry VI


    Penlington, A.


    This essay will consider recent shifts in performance representations of England and the exotic ‘other’ in Shakespeare’s Henry IV, Henry V and Henry VI plays. By tracing the texts’ varied representations of non-English Britons and those for whom English is not their mother tongue (such as Owen Glyndwr in 1 Henry IV and Princess Catherine in Henry V), recent criticism has identified that Shakespeare’s narrative portrays the challenges of assimilating ‘otherness’ within English culture. This es...

  11. Space perception and William James's metaphysical presuppositions. (United States)

    Farrell, Martin J


    William James's overtly philosophical work may be more continuous with his psychological work than is sometimes thought. His Essays in Radical Empiricism can be understood as an explicit statement of the absolute presupposition that formed the basis of Jamesian psychology: that direct experience is primary and has to be taken at face value. An examination of James's theory of space perception suggests that, even in his early work, he presupposed the primacy of direct experience, and that later changes in his account of space perception can be understood as making his view more consistent with this presupposition. In his earlier view of space perception, James argued that sensations were directly experienced as spatial, though he accepted that spatial relations between sensations may be constructed by higher order thought. In his later view, however, James argued that spatial relations were just as directly experienced as sensations. The work of T. H. Green may have prompted James to recognize the full consequence of his ideas and to realize that taking experience at face value required that spatial relations be thought of as intrinsic to experience rather than the result of intellectual construction.

  12. William James, Gustav Fechner, and Early Psychophysics

    Directory of Open Access Journals (Sweden)

    Stephanie L. Hawkins


    Full Text Available American psychologist and philosopher William James devoted the entirety of his career to exploring the nature of volition, as expressed by such phenomena as will, attention, and belief. As part of that endeavor, James's unorthodox scientific pursuits, from his experiments with nitrous oxide and hallucinogenic drugs to his investigation of spiritualist mediums, represent his attempt to address the "hard problems" of consciousness for which his training in brain physiology and experimental psychology could not entirely account. As a student, James's reading in chemistry and physics had sparked his interest in the concepts of energy and force, terms that he later deployed in his writing about consciousness and in his arguments against philosophical monism and scientific materialism, as he developed his radically empiricist ideas privileging discontinuity and plurality. Despite James's long campaign against scientific materialism, he was, however, convinced of the existence of a naturalistic explanation for the more "wayward and fitful" aspects of mind, including transcendent experiences associated with hysteria, genius, and religious ecstasy. In this paper, I examine aspects of James's thought that are still important for contemporary debates in psychology and neuroscience: his "transmission theory" of consciousness, his ideas on the "knowing of things together," and, finally, the related concept of "the compounding of consciousness," which postulates the theoretical possibility for individual entities within a conscious system of thought to "know" the thoughts of others within the system. Taken together, these ideas suggest that James, in spite of, or perhaps because of, his forays into metaphysics, was working toward a naturalistic understanding of consciousness, what I will term a "distributive model," based on his understanding of consciousness as an "awareness" that interacts dynamically within, and in relation to, its environment.

  13. In conversation with: Professor Richard James

    Directory of Open Access Journals (Sweden)

    John Clarke


    Full Text Available In 2011, Richard James wrote in the Foreword to Nelson, Clarke, Kift, and Creagh’s (2012 monograph on Australasian literature on the First Year Experience that:The trend towards universal participation will usher in dramatic changes in the character of the first year in higher education. … (p. iiiIn an interview at the University of Melbourne, Australia in July 2013 between Richard James and John Clarke, Co-editor of the International Journal of the First Year in Higher Education, these and related issues were explored.  The interview picks up where the Foreword left off:  focussing on universal participation.

  14. James Madison University Survey of Faculty Activities. (United States)

    James Madison Univ., Harrisonburg, VA.

    The activities of the faculty at James Madison University during the fall term of the academic year 1978-79 are described. Full-time instructional faculty, part-time faculty involved in resident instruction, administrators and classified employees who taught at least one course, and graduate teaching assistants were surveyed. Information was…

  15. "Restructuring" Stirs Outcry at James Madison. (United States)

    Magner, Denise K.


    An administration plan to discontinue the physics major at James Madison University (Virginia) has raised concerns about the president's leadership and management style, and the role of faculty in institutional decision making. Faculty were notified of the plan only after student leaders were told. (MSE)

  16. James Madison and "The Federalist Papers." (United States)

    Patrick, John J.; And Others

    A collection of resources for high school history and government teachers and their students, this volume treats core ideas on constitutional government in the United States. James Madison's ideas as found in "The Federalist Papers" are examined in conjunction with their counterpoints in essays of the Anti-Federalists. This volume…

  17. James Madison and the Constitutional Convention. (United States)

    Scanlon, Thomas M.


    Part 1 of this three-part article traces James Madison's life and focuses primarily on those events that prepared him for leadership in the U.S. Constitutional Convention of 1787. It describes his early love of learning, education, and public service efforts. Part 2 chronicles Madison's devotion to study and preparation prior to the Constitutional…

  18. James Bernard Russell: Scholar, collaborator, mentor (United States)

    At the time of his untimely death in 2009, ARS scientist Dr. James B. Russell had established himself as the premier rumen microbiologist of his generation. Dr. Russell’s many contributions to the field, including much of the early work on the Cornell Net Carbohydrate System model, were the product ...

  19. In praise of the literary eponym--Henry V sign.

    LENUS (Irish Health Repository)

    Shanahan, F


    The use of eponyms in medicine is often discouraged. However, the literary eponym should be an exception as it is not linked with many of the difficulties associated with conventional eponyms and offers descriptive brevity and accuracy. Here, we illustrate the point with Henry V sign, which will be familiar to many who have cared for patients in the terminal stage of illness.

  20. Henry the Seventh and Italy, an historiographical account

    Directory of Open Access Journals (Sweden)

    Gian Maria Varanini


    Full Text Available The article represents an introduction to the contributions published in the monographic section dedicated to the expedition of Henry VII of Luxembourg in Italy (1310-1313. It provides an historiographic overview and some insightful clues.

  1. The Transformative Intellectual: An Examination of Henry Giroux's Ethics (United States)

    Kashani, Tony


    This article explores Henry Giroux's contributions to critical pedagogy. The author demonstrates how Giroux, as a public intellectual, has found his Ethics in the right place. The author further argues that Giroux's Ethics of virtue are present not only in the public person but also in his transformative writing.

  2. Kesknoored tegid visiidi Šveitsi / Henri Kaselo

    Index Scriptorium Estoniae

    Kaselo, Henri


    Keskerakonna noorte esindus külastas 20.-25. aprillini 2005 Šveitsi, et osaleda sealsete noorte liberaalide Jungfreisinnige Schweizi kongressil. Delegatsiooni kuulusid esimees Tarmo Lausing, välissekretär Olga Sõtnik, endine pressisekretär Raimond Kaljulaid ja noortekogu esimees Henri Kaselo

  3. The Teaching Approach of Henry Schaefer-Simmern. (United States)

    Abrahamson, Roy E.


    This description of the teaching approach of Henry Schaefer-Simmern emphasizes his use of questioning to evoke student self-evaluation and to develop clarity of vision and interfunctional unity in students' art products and their mental, artistic conceiving. Two case reports of his work with elementary students are included. (Author/SJL)

  4. Principles in Action: The Work of Henri Wallon (United States)

    Voyat, Gilbert


    An examination of the life and philosophy of Henri Wallon, A French psychiatrist, psychologist, and educator, focusing on his views regarding the role of imitation in adaptation and learning, emotional development, syncretic thought, his differences with Piaget, and an assessment of the impact of his work. (EH)

  5. La Vie et L'oeuvre d'Henri Wallon. (United States)

    Aubrey, Carol


    Outlines the life and philosophy of noted French child psychologist, Henri Wallon (1879-1962). Reviews the philosophical origins of the Wallonian Approach including the theory of emotions, the development of representational thought, the role of imitation in the formation of representation, and the role of language in the development of thought…

  6. The Failed Educations of John Stuart Mill and Henry Adams. (United States)

    Crossley, Robert


    Analyzes and contrasts Mill's "Autobiography" and Adams'"The Education of Henry Adams" in order to present two approaches to the nature of education and of failure. Maintains that their perspectives may serve as catalysts and cautions for contemporary theories of education and its utility and relevance. (CAM)

  7. Henri Becquerel and the discovery of natural radioactivity

    International Nuclear Information System (INIS)

    Barquins, M.


    This article presents the life and achievements of Henri Becquerel particularly in the domain of natural radioactivity which he discovered. In 1903 H.Becquerel was awarded the Nobel prize of physics (jointly with the Curies). The author highlights the importance of his talent but also the influence of his family background: his grand-father and father were both renowned scientists

  8. Henri Poincaré a biography through the daily papers

    CERN Document Server

    Ginoux, Jean-Marc


    On July 17, 2012, the centenary of Henri Poincaré's death was commemorated; his name being associated with so many fields of knowledge that he was considered as the Last Universalist. In Pure and Applied Mathematics, Physics, Astronomy, Engineering and Philosophy, his works have had a great impact all over the world. Poincaré acquired in his lifetime such a reputation that, both nationally and internationally, his life and career were made the object of various articles in the daily papers not only in France, but also in the USA. Some of his philosophical concepts have even caused sharp controversies in the Press (as we will discover in this book).This work presents an original portrait of Henri Poincaré based on various press cuttings from The New York Times, The San Francisco Sunday Call, The Times, The Sun, The Washington Post that chronicled unknown anecdotes of his life (for example, his first name was actually not Henri, but Henry; he obtained his high school diploma in sciences with a zero in mathem...

  9. 2. Robin Attfield Henry Odera Oruka, Ecophilosophy and Climate ...

    African Journals Online (AJOL)


    Henry Odera Oruka, ecophilosophy, climate change ethics, impacts of climate ... One of the fields of environmental philosophy which he would almost ... engineering, and on “Humanity's Carbon Budget”, followed by Conclusions about ... countries that are largely responsible for these emissions must take the lion's share of.

  10. Comparison of the acute effects of Tulbaghia violacea William Henry ...

    African Journals Online (AJOL)

    Purpose: To assess the effect of the crude methanol leaf extracts of Tulbaghia violacea William Henry Harvey (Alliaceae) on blood pressure (BP) and heart rate in ageing normotensive Wistar Kyoto rats (WKY), and compare the results obtained with those for adult spontaneously hypertensive rats (SHR). Methods: T.

  11. Potential Beneficial Effects of Tulbaghia violacea William Henry ...

    African Journals Online (AJOL)

    Tulbaghia violacea William Henry Harvey (Harv. Alliaceae) is a small bulbous herb belonging to the family Alliaceae. It is used in South Africa to treat fever, colds, asthma, paralysis, and hypertension. Meanwhile, cardiovascular disease accounts for about 30 % of total global death, with most of these deaths occurring in low ...

  12. Tribute to the legend Mr. Veterinary Public Health, Professor James ...

    African Journals Online (AJOL)

    The author was also destined during his Sabbatical Leave to have an interactive interview session with Prof James Steele after attending the 20th Annual James Steele lecture/ 99th birthday Dinner of Professor James Steele 4th and 6th April 2012 at the Texas School of Public Health, Houston, Texas, USA. The interview ...

  13. Thomas Henry Huxley et la Bible Thomas Henry Huxley and the Bible

    Directory of Open Access Journals (Sweden)

    Christophe Duvey


    Full Text Available Thomas Henry Huxley devoted several essays to the study of the Bible. This interest can only be accounted for if his ideas on history, religion as well as epistemology are examined. According to him, a struggle between free thought and supernaturalism was culminating during the Victorian era, hence the need for a “New Reformation” which was heir to the ideals of freedom defended by the humanists of the Renaissance. This movement opposed the principles of the supporters of what he called “ecclesiasticism”. The advocates of the “New Reformation” could rely on the progress of modern science, and agnosticism, which Huxley identified with scientific method, became its epistemological foundation. As a result, Huxley thought that the authority of physical science was in conflict with the infallibility of the Scriptures and with the theological arguments which rested on it, and this notably led him to the conclusion that the biblical narrative of the Flood was unhistorical. The naturalisation of the Scriptures seems then logically to follow his philosophical views based on the limits of human knowledge.It appears that it was the question of authority which underlay Huxley’s interest in the Bible. He thought that the authority of the Scriptures must be replaced by that of science.

  14. Obituary: Roy Henry Garstang (1925-2009) (United States)

    Malville, J.


    Roy Henry Garstang 84 passed away on November 1, 2009 in Boulder Colorado. He was born in Southport, England in September of 1925 to Percy Brocklehurst and Eunice (Gledhill) Garstang. He won a scholarship to Caius College in Cambridge University. Because it was wartime, he could spend only two years at his studies. However, he managed to complete three years of required work during that time, and then spent 1945-46 as a Junior Scientific Officer at the Royal Aircraft Establishment at Farnborough. He received his BA in 1946 from Cambridge, his MA in 1950, and his PhD in Mathematics in 1954, with a thesis: "Atomic Transitions in Astrophysics," working under D. R. Hartree. He also received a ScD from Cambridge in Physics and Chemistry in 1983. He married Ann in August 1959. She and two daughters, Jennifer and Susan, survive him. While still pursuing his PhD, Roy Garstang served as a Research Associate at the Yerkes Observatory, from 1951-1952, working under Subrahmanyan Chandrasekhar. During that time he continued with his own calculations of atomic structure and transition probabilities, although these were not part of Chandra's research interests. After earning his PhD, he went to teach at the University of London, where he also served as the Assistant Director of the University of London Observatory (1959-1964). He was editor of "The Observatory" Magazine form 1953-1960. The continuing theme of this research was to help meet the needs of astrophysicists for atomic data. In 1964, he left England for the United States, where he joined the faculty at the University of Colorado, Boulder, where he would remain for the rest of his professional career. It was entirely fitting, considering his interest in performing calculations of interest to astrophysicists, that soon after arriving in Boulder he was appointed Chairman of JILA - Joint Institute for Laboratory Astrophysics (1966-1967). He was Director of the Division of Physics and AstroGeophysics (1979-80), acting

  15. A Reading of Joseph Conrad's The Tale


    Zadeh, Mohammad Reza Modarres


    The Tale is a short story by Joseph Conrad. Typical of a Conrad story it is set at sea. The sea is symbolic of the unconscious and this story may be read as a story of the unconscious. On the outside, it seems simple; a man tells a woman a tale of the commanding officer of a patrol ship who gives false directions to another ship and sends it to its doom. In between the lines of the seemingly simple plot, however, can be read another tale; one which speaks of a human sea deeper than the sea of...

  16. Real and étale cohomology

    CERN Document Server

    Scheiderer, Claus


    This book makes a systematic study of the relations between the étale cohomology of a scheme and the orderings of its residue fields. A major result is that in high degrees, étale cohomology is cohomology of the real spectrum. It also contains new contributions in group cohomology and in topos theory. It is of interest to graduate students and researchers who work in algebraic geometry (not only real) and have some familiarity with the basics of étale cohomology and Grothendieck sites. Independently, it is of interest to people working in the cohomology theory of groups or in topos theory.

  17. [Delocalizing the mind. Peirce, James, Wittgenstein, Descombes]. (United States)

    Chauviré, Christiane


    The cognitive sciences have breathed fresh air into the old problem of localizing mental functions, which was often laughed off. Regarding the most philosophical form of the question on the localization of the mind, authors such as Peirce, James, Wittgenstein, and most recently Descombes have imagined delocalizing the mind in order to spread the conviction that the idea itself of a location of the mental is meaningless and to criticize the localisationism of today's cognitive scientists.

  18. Tales of physicists and mathematicians

    CERN Document Server

    Gindikin, Semyon Grigorevich


    This revised and greatly expanded second edition of the classic Russian text Tales of Mathematicians and Physicists contains a wealth of new information about the lives and accomplishments of more than a dozen scientists throughout history. Included are individuals from the late nineteenth century: Klein, Poincaré, Ramanujan, and Penrose, as well as renowned figures from earlier eras, such as Leibniz, Euler, Lagrange, and Laplace. A unique mixture of mathematics, physics, and history, this volume provides biographical glimpses of scientists and their contributions in the context of the social and political background of their times. The author examines many original sources, from the scientists’ research papers to their personal documents and letters to friends and family; furthermore, detailed mathematical arguments and diagrams are supplied to help explain some of the most significant discoveries in calculus, celestial mechanics, number theory, and modern relativity. What emerges are intriguing, multifac...

  19. William James and the Heidelberg fiasco. (United States)

    Gundlach, Horst


    Urged on by his father to become a physician instead of a painter, William James pursued 3 evasion stratagems. First, to avoid becoming a practitioner, he declared that he wanted to specialize in physiology. Based upon this premise, he left for Germany in the spring of 1867. The second step was giving up general physiology and announcing that he would specialize in the nervous system and psychology. Based upon this premise, he declared that he would go to Heidelberg and study with Helmholtz and Wundt. However, he then deferred going there. When, at last, he was urged by an influential friend of his father's to accompany him to Heidelberg, he employed his default stratagem: He simply fled. He returned home after 3 terms in Europe without enrolling at a single university. There is no evidence that he had learned anything there about psychology or experimental psychology, except, possibly, by reading books. James's "Heidelberg fiasco" was the apogee of his evasion of his father's directive. A dense fog of misinformation surrounds his stay in Heidelberg to this day. By analyzing circumstances and context, this article examines the fiasco and places it in the pattern of his behavior during his stay in Europe. Nevertheless, experiencing this fiasco potentially shaped James's ambivalent attitude toward experimental psychology on a long-term basis. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  20. TALE nucleases and next generation GM crops.

    KAUST Repository

    Mahfouz, Magdy M.; Li, Lixin


    Site-specific and adaptable DNA binding domains are essential modules to develop genome engineering technologies for crop improvement. Transcription activator-like effectors (TALEs) proteins are used to provide a highly specific and adaptable DNA

  1. "Thou" and "Ye" in Chaucer's "Clerk's Tale." (United States)

    Wilcockson, Colin


    Examines the use of the second person pronoun in Chaucer's "Clerk's Tale" to demonstrate that students of medieval texts may well miss important areas of meaning if they fail to give adequate attention to the historical study of language. (GT)

  2. Tegn kan også Tale

    DEFF Research Database (Denmark)

    Fischer, Jutta; Niebe, Susanne; Bisgaard, Hanne

    "Tegn kan også Tale" er et begyndermateriale til undervisning af syns- og hørehæmmede døvblindblevne i taktil tegnstøttet kommunikation - en ny taktil kommunikationsform, som bygger på det danske sprog og bruger tegn og andre elementer fra døves tegnsprog. Tegn kan også Tale´ henvender sig primær...


    Directory of Open Access Journals (Sweden)



    Full Text Available In this paper I presented the innovation and entrepeneurial creativity as a basis in the process of business redesign. I chose as a case study the the Ford brand products, because it is considered that Henry Ford is one of the greatest innovators and entrepreneurs of all time and I decided to present and to analyze these things. The first part of the paper will include theoretical approaches on the innovation and creativity business concepts and premises, and then I showed the ways in which four types of economic innovation under the leadership of Henry Ford (innovation in product, in process, market and organizational were achieved, with the purpose to recognize them in other companies, nowadays .

  4. The Vanadium Window with special reference to Joseph and James Flannery's contribution to the American steel and radium industries

    International Nuclear Information System (INIS)

    Lubenau, J. O.; Mould, R. F.


    The discovery of vanadium is described and the founding of the American Vanadium Company by Joseph Flannery (1867-1920) and its headquarters building in Pittsburgh in which was the stained glass window depicting the origin of the name Vanadium. Company orders for vanadium steel were obtained for the Panama canal and from Henry Ford. When his sister was diagnosed with cancer, Joseph Flannery withdrew from his vanadium interests and founded the Standard Chemical and Radium Chemical Companies which were the major suppliers of radium in the USA in the 1920s (before the Union Minicre du Haut Katanga commenced its commercial operations), processed from American mined carnotite in Colorado and Utah. Significant contributions to these enterprises involving vanadium and radium were also made by Joseph's elder brother, James Flannery (1848-1920). (author)

  5. Iraagi olukorral on poliitiline lahendus / Henry A. Kissinger

    Index Scriptorium Estoniae

    Kissinger, Henry, 1923-


    USA endine riigisekretär Henry Kissinger kirjutab, et Ameerika Ühendriikide eesmärgiks peaks olema riikidevaheline kokkulepe, mis tunnistaks Iraagi rahvusvahelist staatust. See oleks vägivalla lõpetamiseks hea alus ja eeltingimuseks vägede väljaviimisele. Vt. samas: Ameerika Ühendriikide vahekokkuvõte Iraagi sõja kohta oli suhteliselt pessimistlik

  6. Should bulk cloudwater or fogwater samples obey Henry's law? (United States)

    Pandis, Spyros N.; Seinfeld, John H.


    Mixing of droplets with different pH that are individually in Henry's law equilibrium with the surrounding atmosphere always results in a bulk mixture that is supersaturated with weak acids like S(IV) and HCOOH, and bases like NH3 with respect to the original atmosphere. High supersaturations result only when the pH of the bulk droplet mixture exceeds the pKa of the species, in which pH range large pH differences among droplets of different sizes lead to large deviations from Henry's law for the bulk mixture. The deviation is shown to depend on the ratio of the arithmetic mean to the harmonic mean of the hydrogen ion concentrations of the droplets with the liquid water content used as weighting factor in the calculation of the means. The theory developed can explain observed discrepancies from Henry's law in atmospheric samples and also other observed phenomena like the reported increase of pH values of bulk aqueous samples during storage.

  7. James Bernoulli与《推测术》%James Bernoulli and Stochastics

    Institute of Scientific and Technical Information of China (English)



    Two hundred and eighty-nine years ago, "Arts of conjecturing", the posthumous work of the great mathematician James Bernoulli, was finally produced in the eager wait of mathematicians, Ian Hacking, a famous historian of statistics, commented that the publication of the book signaled the beginning of the mathematical theory of probability and terminated man's long process in the forming of the probability concept By introducing James Bernoulli and his "Arts of conjecturing", this paper aims at providing the reader with the 18th century story of Bemoulli's work, and at making the reader know that even today Bemoulli's idea is very helpful and instructive in the research of modern statistics.

  8. A case of Swyer-James syndrome

    International Nuclear Information System (INIS)

    Suzuki, Toshimitsu; Ohtani, Naoshi; Kimura, Sohichi; Izuchi, Rokuro; Iio, Masaaki; Fujinami, Kenji.


    Infantile infections are thought to constitute one of the main bases of the etiology of Swyer-James syndrome. This case seems to support the above theory allowing for the anamnesis of the pleuritis at 2 years of age, bronchographical findings - bilateral but markedly left-sided bud-like bronchiectatic changes - and left pulmonary angiographical findings - simultaneous appearance of pulmonary arteries and veins with scarce capillary image. Concerning the ventilation of this syndrome, 133 Xe inhalation test showed a ''Pendelluft'' phenomenon, shift of 133 Xe from the healthy to the affected lung on forced expiration. (author)

  9. A Fairy-Tale Landscape (United States)


    [figure removed for brevity, see original site] Click on image for animation Fun, fairy-tale nicknames have been assigned to features in this animated view of the workspace reachable by the robotic arm of NASA's Phoenix Mars Lander. For example, 'Sleepy Hollow' denotes a trench and 'Headless' designates a rock. A 'National Park,' marked by purple text and a purple arrow, has been set aside for protection until scientists and engineers have tested the operation of the robotic scoop. First touches with the scoop will be to the left of the 'National Park' line. Scientists use such informal names for easy identification of features of interest during the mission. In this view, rocks are circled in yellow, other areas of interest in green. The images were taken by the lander's 7-foot mast camera, called the Surface Stereo Imager. The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

  10. The Category of Time in Fairy Tales: Searching for Folk Calendar Time in the Estonian Fairy Tale Corpus

    Directory of Open Access Journals (Sweden)

    Mairi Kaasik


    Full Text Available The article examines how folk calendar holidays are represented in Estonian fairy tales. It introduces some views presented in folklore studies about the concept of time in fairy tales and finds parallels with them in the Estonian context. The analysis relies on the digital corpus of Estonian fairy tales (5400 variants, created from the texts found in the Estonian Folklore Archives by the Fairy Tale Project of the Department of Estonian and Comparative Folklore, University of Tartu. Folk calendar holidays occur in Estonian fairy tales relatively seldom; most often these are holidays that occupy a significant place in the Estonian folk calendar (Christmas, St. John’s Day, Easter, St. George’s Day. Calendar holidays are notably mentioned more often in tale types which remain on the borderline between the fairy tale and the legend or the fairy tale and the religious tale. In Estonian fairy tales, calendar holidays are used on three levels of meaning: (1 the holiday is organically associated with the tale type; it has an essential role in the plot of the tale; (2 to a certain extent, the holiday could be replaced by another holiday having an analogous meaning; (3 the holiday forms an unimportant or occasional addition to the tale.

  11. Kuula. Kellele ei meeldiks James Blunt? / Mart Juur

    Index Scriptorium Estoniae

    Juur, Mart, 1964-


    Heliplaatidest: James Blunt "Back To Bedlam", Enrique Iglesias "Insomniac", Prince "Planet Earth", Garbage "Absolut Garbage", Justice "Cross", Interpol "Our Love To Admire", Rufus Wainwright "Release The Stars"

  12. Robust, synergistic regulation of human gene expression using TALE activators. (United States)

    Maeder, Morgan L; Linder, Samantha J; Reyon, Deepak; Angstman, James F; Fu, Yanfang; Sander, Jeffry D; Joung, J Keith


    Artificial activators designed using transcription activator-like effector (TALE) technology have broad utility, but previous studies suggest that these monomeric proteins often exhibit low activities. Here we demonstrate that TALE activators can robustly function individually or in synergistic combinations to increase expression of endogenous human genes over wide dynamic ranges. These findings will encourage applications of TALE activators for research and therapy, and guide design of monomeric TALE-based fusion proteins.

  13. Rahvaliit : Henri Kaselo süüdistus on idiootsus / Jüri Saar

    Index Scriptorium Estoniae

    Saar, Jüri, 1946-


    Keskerakonna Tartumaa piirkonna esimeheks valitud Tartu linnavolinik Henri Kaselo kritiseeris teravalt Rahvaliitu kuuluvaid Tartumaa vallajuhte, kelle juhtimisstiil ja korruptiivne poliitika polevat nõukogude ajast muutunud

  14. [From apprenticeship to Nobel Prize: Henri Moissan's fabulous destiny]. (United States)

    Lafont, O


    Born in Paris on September 28, 1852, son of an eastern railways' employee and of a dressmaker, Henri Moissan's secondary schooling in Meaux did not allow him to get access to the sesame diploma "baccalauréat" (GCE). In 1869, he did obtain a special certificate of secondary schooling so that he could become an apprentice in watch making. That could have been the end of the story, but dreadful event for France appeared to have beneficial effects for Moissan. Under the threat of the Prussian army, Moissan's family took refuge near Paris. This gave the young Henri the opportunity to register as a student for the second-class pharmacy diploma, which did not need, at the time, the GCE. Moissan became then a trainee in pharmacy in 1871. Meanwhile, he followed the special schooling of "Ecole de chimie" founded by E. Frémy, and then joined the laboratory of Dehérain at the Museum, where he worked in plant physiology. He finally obtained the famous "baccalauréat" (GCE) and could register as a student in first-class pharmacy. He became a pharmacist as well as a doctor in sciences. In 1883, Moissan was named professor at the school of pharmacy in Paris. In 1886, he isolated fluorine by electrolysis of fluorhydric acid, in the presence of potassium fluoride, at a low temperature. He then studied diamond synthesis and gave a start to high temperature chemistry, designing his famous furnace. These findings and many others allowed Moissan to rise to membership in many learned academies around the world. Crowning achievement, Moissan won the Nobel Prize in 1906. A man of culture, collector of autographs and paintings, he died in 1907. Nothing of that would have been possible if there had not been a second-class pharmacist diploma. The history of Henri Moissan is one of a rise from apprenticeship to the Nobel Prize.

  15. TALE nucleases and next generation GM crops.

    KAUST Repository

    Mahfouz, Magdy M.


    Site-specific and adaptable DNA binding domains are essential modules to develop genome engineering technologies for crop improvement. Transcription activator-like effectors (TALEs) proteins are used to provide a highly specific and adaptable DNA binding modules. TALE chimeric nucleases (TALENs) were used to generate site-specific double strand breaks (DSBs) in vitro and in yeast, Caenorhabditis elegans, mammalian and plant cells. The genomic DSBs can be generated at predefined and user-selected loci and repaired by either the non-homologous end joining (NHEJ) or homology dependent repair (HDR). Thus, TALENs can be used to achieve site-specific gene addition, stacking, deletion or inactivation. TALE-based genome engineering tools should be powerful to develop new agricultural biotechnology approaches for crop improvement. Here, we discuss the recent research and the potential applications of TALENs to accelerate the generation of genomic variants through targeted mutagenesis and to produce a non-transgenic GM crops with the desired phenotype.

  16. Singing Dead Tales to Life: Rhetorical Strategies in Shandong Fast Tales

    Directory of Open Access Journals (Sweden)

    Eric Shepherd


    Full Text Available This article provides a brief overview of the Shandong fast tale tradition, a Chinese oral performance genre that began in rural northern China approximately four hundred years ago. Included in this overview are brief descriptions of the origins, audience composition, tale length, repertoire, and major characteristics of the stories and performances. Following these descriptions is a discussion of the expressive and rhetorical devices used by the tale-tellers as they perform live, such as formulaic language, repetition, character roles, shifts in speech register, body language, facial expressions, memory, onomatopoeia, physical humor, and hyperbolic language.

  17. O pensamento crítico de Henri Lefebvre

    Directory of Open Access Journals (Sweden)

    William Gómez Soto


    Full Text Available Este trabalho é uma análise da presença de Henri Lefebvre na sociologia brasileira. Lefebvre faz uma leitura crítica de Marx, recuperando o método dialético e propondo uma teoria da vida cotidiana. José de Souza Martins influenciado por Lefebvre e utilizando o método dialético, analisa o processo histórico da constituição do capitalismo brasileiro. Apesar de que há certa presença de Lefebvre na sociologia brasileira, ainda a riqueza de sua obra está para ser descoberta.

  18. Henry Duméry and the sacredness of history


    Labèque, Marcelo Horacio; Pontificia Universidad Católica Argentina


    Following the steps of the French phenomenologist HenryDuméry, It is pursued to identify the particularities of what have been called before the «historical sacred», in the most general frame of a «morphology of sacred». In that sense it is intended to demonstrate that the originality of the experience and configuration of the sacred, in both Jewish and Christian religion, comes out from a transformation of cosmic archaic experiences and points of view, leading into a new way of sacred that g...

  19. Edward Henry Sieveking and the demise of essential epilepsy. (United States)

    Bladin, Peter F


    Edward Henry Sieveking, eminent London physician of Victorian times, is best known as the speaker at the historic meeting at which the chairman, Sir Charles Locock, seem to overshadow him in announcing the introduction of bromide--the first effective anti-convulsant. But in fact Sieveking had announced a most important conceptual advance in epileptology--the demise of "essential epilepsy". In addition his book, published soon after and based upon his lecture, is an important historical resumé of Victorian era concepts and management of epilepsy. His important contributions to the understanding and management of this condition are discussed herein.

  20. Henri Ey's neojacksonism and the psychopathology of disintegrated mind. (United States)

    Farina, Benedetto; Ceccarelli, Maurizio; Di Giannantonio, Massimo


    The French psychiatrist Henri Ey developed his organo-dynamic theory of the mind function and consciousness 50 years ago incorporating Hughling Jackson's thinking, along with psychiatric and philosophical theorizations by Janet and Bergson. This model has not received the attention it deserved, but recent advances in neuroscience rekindled interest for Ey's theory. By overcoming the Cartesian mind-body dualism and treating the mind-body unit as an inseparable whole, this model opens the way for the integrated treatment of mental disorders. Ey's conceptualization of consciousness as being simultaneously both synchronous and diachronic anticipates current theories of consciousness (Damasio, Edelman, Mesulam).

  1. Stapp`s quantum dualism: The James/Heisenberg model of consciousness

    Energy Technology Data Exchange (ETDEWEB)

    Noyes, H.P.


    Henry Stapp attempts to resolve the Cartesian dilemma by introducing what the author would characterize as an ontological dualism between mind and matter. His model for mind comes from William James` description of conscious events and for matter from Werner Heisenberg`s ontological model for quantum events (wave function collapse). His demonstration of the isomorphism between the two types of events is successful, but in the author`s opinion fails to establish a monistic, scientific theory. The author traces Stapp`s failure to his adamant rejection of arbitrariness, or `randomness`. This makes it impossible for him (or for Bohr and Pauli before him) to understand the power of Darwin`s explanation of biology, let along the triumphs of modern `neo-Darwinism`. The author notes that the point at issue is a modern version of the unresolved opposition between Leucippus and Democritus on one side and Epicurus on the other. Stapp`s views are contrasted with recent discussions of consciousness by two eminent biologists: Crick and Edelman. They locate the problem firmly in the context of natural selection on the surface of the earth. Their approaches provide a sound basis for further scientific work. The author briefly examines the connection between this scientific (rather than ontological) framework and the new fundamental theory based on bit-strings and the combinatorial hierarchy.

  2. Fantasmas de si mesmo: uma leitura demoníaca de James e de Machado

    Directory of Open Access Journals (Sweden)

    Marcelo Pen Parreira

    Full Text Available Este artigo prossegue na discussão sobre o papel do duplo no mundo desencantado da era liberal. Por meio da análise de algumas histórias de Henry James e de Machado de Assis, ele investiga a figuração do sujeito, esvaziado e iludido, assombrado por seu outro eu mutilado - imagem replicada tornada pavorosa pelo horror que o homem moderno comete contra si próprio. As narrativas de Machado, além disso, ao evocar personagens como que possuídos por vestígios de sua "herança bestial" ou por projeções de feitos mundanos (que eles metonimicamente tomam como sua essência integral, desestabilizam ainda mais o conceito de individuação. Nos dois autores, lidar com esse paradoxo também significa conduzir a narrativa a seus momentos negativos ou de falência, quando narrar deixa de ser possível.

  3. James Cronin, CP Violation, and the Pierre Auger Observatory (United States)

    dropdown arrow Site Map A-Z Index Menu Synopsis James Cronin, CP Violation and the Pierre Auger Observatory matter over antimatter."1 "The experiment uncovered the CP [charge-parity] violation, or a with Additional Information Additional information about James Cronin and the charge-parity (CP

  4. James Madison High School. A Curriculum for American Students. (United States)

    Bennett, William J.

    This document presents the Secretary of Education's personal concept of a sound secondary school core curriculum. It is called "James Madison High School" in honor of President James Madison and his strong views that the people, in order to govern properly, must arm themselves with knowledge. The theoretical curriculum consists of four…

  5. James Hillman: Toward a poetic psychology. (United States)

    Avens, R


    InThe Dream and the Underworld James Hillman continues to deepen and to refine Jung's recovery of the spontaneous image-making of the soul. Hillman's contribution lies in his "imaginai reduction"-relating of images to their archetypal background in Greek mythology. Myth is seen as the maker of the psyche, and, in turn, the soul-making ispoesis-a return to the imaginal and poetic basis of consciousness. Dreams, understood poetically, are neither messages to be deciphered and used for the benefit of the rational ego (Freud) nor compensatory to the ego (Jung); they are complete in themselves and must be allowed to speak for themselves. Hillman also sees dreams as initiations into the underworld of death-the other side of life where our imaginal substance is unobstructed by the literal and dualistic standpoints of the dayworld.

  6. Evaluating Henry's law constant of N-nitrosodimethylamine (NDMA). (United States)

    Haruta, Shinsuke; Jiao, Wentao; Chen, Weiping; Chang, Andrew C; Gan, Jay


    N-Nitrosodimethylamine (NDMA), a potential carcinogen, may contaminate the groundwater when the reclaimed wastewater is used for irrigation and groundwater recharge. Henry's law constant is a critical parameter to assess the fate and transport of reclaimed wastewater-borne NDMA in the soil profile. We conducted a laboratory experiment in which the change of NDMA concentration in water exposed to the atmosphere was measured with respect to time and, based on the data, obtained the dimensionless Henry's law constant (K(H)') of NDMA, at 1.0 x 10(-4). The K(H)' suggests that NDMA has a relatively high potential to volatilize in the field where NDMA-containing wastewater is used for irrigation and the volatilization loss may be a significant pathway of NDMA transport. The experiment was based on the two boundary-layer approach of mass transfer at the atmosphere-water interface. It is an expedient method to delineate K(H)' for volatile or semi-volatile compounds present in water at low concentrations.

  7. James Wallbank (Redundant Technology Initiative) (RTI) / James Wallbank ; interv. Tilman Baumgärtel

    Index Scriptorium Estoniae

    Wallbank, James


    James Wallbank (sünd. 1966) on RTI (Aegunud Tehnoloogia Initsiatiiv), mis hoiab alates 2000. aastast käigus Interneti-kohvikut "Access Space") Sheffieldis, rajaja. J. Wallbank 6. 10. 2000 tehtud intervjuus RTI-st, mis kasutab oma installatsioonides, skulptuurides ja teistes madaltehnoloogilistes teostes vanu arvuteid, installatsioonist näitusel "net_condition" Karlssruhe Kunsti- ja Meediatehnoloogia Keskuses (1999), tööst "Network Low Tech Video Wall" (2000) ja muust

  8. “Too Long in Foreign Parts”?: An Asian Reception to Cosmopolitanism in Henry James’s The American and The Portrait of a Lady

    Directory of Open Access Journals (Sweden)

    Patricia Haseltine


    Full Text Available The works of Henry James with their attention to cosmopolitanism in the late nineteenth and early twentieth centuries provide valuable insight into contemporary expectations of cultural hybridity and globalism. This paper assesses the ways students studying English as a foreign language in Taiwan read the cultural exchanges between Americans and Europeans in James’s "The American" (1877 and "The Portrait of a Lady" (1881. It places the main attention upon how students evaluate James’s characters based upon their own attitudes toward cosmopolitanism, work and leisure, and women’s independence. Informed by the travel theory of Mary Louise Pratt (2008 and Homi Bhabha’s (1994 concept of the third space, it studies the negotiation and subversion of meaning in postcolonial and reverse-colonial contexts. The analysis of student responses reveals that in this culturally hybrid reading site, the limited consciousness technique of James generates judgments of characters’ potentialities based upon the students’ own values. Reconciling the cultural oppositions in the self to become a citizen of the world remains an ideal they do not see fully realized in James’s highly conflicted characters, and, as their own partial views attest, not realizable in their own lives.

  9. VoxHenry: FFT-Accelerated Inductance Extraction for Voxelized Geometries

    KAUST Repository

    Yucel, Abdulkadir C.


    VoxHenry, a fast Fourier transform (FFT)-accelerated integral-equation-based simulator for extracting frequency-dependent inductances and resistances of structures discretized by voxels, is presented. VoxHenry shares many features with the popular inductance extractor, FastHenry. Just like FastHenry, VoxHenry solves a combination of the electric volume integral equation and the current continuity equation, but with three distinctions that make VoxHenry suitable and extremely efficient for analyzing voxelized geometries: 1) it leverages a carefully selected set of piecewise-constant and piecewise-linear basis functions; 2) it exploits FFTs to accelerate the matrix-vector multiplications during the iterative solution of system of equations; and 3) it employs a sparse preconditioner to ensure the rapid convergence of iterative solution. VoxHenry is capable of accurately computing frequency-dependent inductances and resistances of arbitrarily shaped and large-scale structures on a desktop computer. The accuracy, efficiency, and applicability of VoxHenry are demonstrated through inductance analysis of various structures, including square and circular coils as well as arrays of RF inductors (situated over ground planes).

  10. Semi-étale groupoids and applications

    DEFF Research Database (Denmark)

    Thomsen, Klaus


    We associate a C * -algebra to a locally compact Hausdorff groupoid with the property that the range map is locally injective. The construction generalizes J. Renault’s reduced groupoid C * -algebra of an étale groupoid and has the advantage that it works for the groupoid arising from a locally i...

  11. Tales of evaluation in school mathematics

    DEFF Research Database (Denmark)

    Andrade-Molina, Melissa


    This is the tale of the power effects of evaluation in the shaping of the desired child. It maps, by using historical and cultural strategies, the circulating truths about standardized assessments, about the need for learning mathematics, and about the axiomatization of space. The analysis takes ...

  12. "Clockwork": Philip Pullman's Posthuman Fairy Tale (United States)

    Gooding, Richard


    This article examines the connections between posthumanism and narrative form in Philip Pullman's "Clockwork." Beginning with an account of Pullman's materialism, it argues that the novel represents consciousness and agency as emergent properties of matter, a position that manifests itself first in the tale's figurative language and later in the…

  13. Law as a Tale of Identity

    DEFF Research Database (Denmark)

    Schaumburg-Müller, Sten


    Understanding law as a tale of identity, indentity includes what we ought as much as what we are. Criticism of law and literature of seing literature as having precende over law which is a mere technicality. Different human rights consceptions in Denmark compared to Europe equal diffent identities....

  14. Activation of silenced cytokine gene promoters by the synergistic effect of TBP-TALE and VP64-TALE activators. (United States)

    Anthony, Kim; More, Abhijit; Zhang, Xiaoliu


    Recent work has shown that the combinatorial use of multiple TALE activators can selectively activate certain cellular genes in inaccessible chromatin regions. In this study, we aimed to interrogate the activation potential of TALEs upon transcriptionally silenced immune genes in the context of non-immune cells. We designed a unique strategy, in which a single TALE fused to the TATA-box binding protein (TBP-TALE) is coupled with multiple VP64-TALE activators. We found that our strategy is significantly more potent than multiple TALE activators alone in activating expression of IL-2 and GM-CSF in diverse cell origins in which both genes are otherwise completely silenced. Chromatin analysis revealed that the gene activation was due in part to displacement of a distinctly positioned nucleosome. These studies provide a novel epigenetic mechanism for artificial gene induction and have important implications for targeted cancer immunotherapy, DNA vaccine development, as well as rational design of TALE activators.

  15. Henri Pirenne: Historian and Man of the World

    Directory of Open Access Journals (Sweden)

    Sarah Keymeulen


    Full Text Available Henri Pirenne (1862-1935 is generally recognised as one of the most influential European historians of the late nineteenth- and early twentieth-century. The combination of his scholarly activity with the social mission that he set himself earned him an extraordinarily successful career and a double reputation: at least in Belgium, he was regarded not only as a ‘father of history’, but also as great citizen. Although his influence was unmistakably large, there is no consensus about the existence or the nature of a ‘Pirennian persona’. He combined the ideal collection of skills, values and standards required of historians with very specific personal characteristics. At the same time he was inextricably linked to a certain era and a certain Belgium that died with him. Pirenne therefore, did not so much represent a new type of scientific persona as the prestige of an idealised, long-vanished Belgium and its corresponding academic culture. Henri Pirenne. Historicus en man van de wereldHenri Pirenne (1862-1935 wordt beschouwd als één van de meest invloedrijke Europese geschiedschrijvers van de laatnegentiende en vroegtwintigste eeuw. Het verband tussen zijn wetenschappelijke activiteit en de maatschappelijke taak die hij voor zichzelf zag weggelegd, leverde hem een uitzonderlijk succesvolle carrière en een dubbele reputatie op. Pirenne staat, althans in België, immers niet alleen geboekstaafd als een ‘vader van de geschiedenis’, maar ook als een groot staatsburger. Hoewel de invloed van Pirenne onmiskenbaar groot is geweest, is er geen consensus over het bestaan of de aard van een ‘pirenniaanse persona’. Hij combineerde het ideaalpakket van vaardigheden, normen en waarden die historici werden geacht te bezitten met zeer specifieke karaktereigenschappen. Tegelijk was hij onlosmakelijk verknoopt met een zeker tijdsgewricht en een zeker België, dat samen met hem ter ziele ging. Pirenne stond dan ook niet zozeer model voor een nieuw

  16. Henri Pirenne: Historian and Man of the World.

    Directory of Open Access Journals (Sweden)

    S. Keymeulen


    Full Text Available Henri Pirenne (1862-1935 is generally recognised as one of the most influential European historians of the late nineteenth- and early twentieth-century. The combination of his scholarly activity with the social mission that he set himself earned him an extraordinarily successful career and a double reputation: at least in Belgium, he was regarded not only as a ‘father of history’, but also as great citizen. Although his influence was unmistakably large, there is no consensus about the existence or the nature of a ‘Pirennian persona’. He combined the ideal collection of skills, values and standards required of historians with very specific personal characteristics. At the same time he was inextricably linked to a certain era and a certain Belgium that died with him. Pirenne therefore, did not so much represent a new type of scientific persona as the prestige of an idealised, long-vanished Belgium and its corresponding academic culture. Henri Pirenne. Historicus en man van de wereld. Henri Pirenne (1862-1935 wordt beschouwd als één van de meest invloedrijke Europese geschiedschrijvers van de laatnegentiende en vroegtwintigste eeuw. Het verband tussen zijn wetenschappelijke activiteit en de maatschappelijke taak die hij voor zichzelf zag weggelegd, leverde hem een uitzonderlijk succesvolle carrière en een dubbele reputatie op. Pirenne staat, althans in België, immers niet alleen geboekstaafd als een ‘vader van de geschiedenis’, maar ook als een groot staatsburger. Hoewel de invloed van Pirenne onmiskenbaar groot is geweest, is er geen consensus over het bestaan of de aard van een ‘pirenniaanse persona’. Hij combineerde het ideaalpakket van vaardigheden, normen en waarden die historici werden geacht te bezitten met zeer specifieke karaktereigenschappen. Tegelijk was hij onlosmakelijk verknoopt met een zeker tijdsgewricht en een zeker België, dat samen met hem ter ziele ging. Pirenne stond dan ook niet zozeer model voor een nieuw

  17. Social and environmental impacts of the James Bay hydroelectric project

    International Nuclear Information System (INIS)

    Hornig, J.F.


    The book, which is an analysis and not an advocacy, examines the anatomy of the controversy that has swirled around the James Bay project - the La Grande and Great Whale projects combined - from the 1970s to the 1990s, and seeks, in the process, to determine whether there are lessons that can be learned from such an analysis that are applicable to other cases as well as to James Bay itself. The contributors are interested, at one and the same time, in finding ways to integrate the knowledge of natural scientists and social scientists to deepen the understanding of human/environment relations and to link science and policy to encourage a productive dialogue between practitioners and scholars in this increasingly important area of inquiry. The contributor's papers include the following: introduction to the issues; hydroelectric power development at James Bay: establishing a frame of reference; James Bay: environmental considerations for building large hydroelectric dams and reservoirs in Quebec; elevated mercury in fish as a result of the James Bay hydroelectric power development: perception and reality; the Cree people of James Bay: assessing the social impacts of hydroelectric dams and reservoirs; culture, social change, and Cree opposition to the James Bay hydroelectric development; and the impact of James Bay hydroelectric development on the art and craft of the James Bay Cree. The authors of the volume have attempted to stand back and examine just a few of these issues from the perspective of a variety of disciplines, and their purpose is to inform and stimulate thoughtful consideration by providing an overall perspective that might might serve to broaden the context in which specific issues can be debated. refs., 3 tabs., 5 figs

  18. História e psicologia em Henri Berr


    Waeny, Maria Fernanda Costa


    O artigo aborda algumas das idéias de Henri Berr; trata de sua proposta em história, especialmente no que ela se opõe à filosofia da história e à história alemãs; e examina como esta concepção de história à la francesa introduz a psicologia nas pesquisas em história e inaugura a psicologia histórica.Palavras-chave: História da Psicologia; Psicologia Histórica; História das Ciências Humanas; História das Idéias; Annales

  19. Henri de Régnier portraitiste du Parnasse


    Mortelette, Yann


    Henri de Régnier disait de José-Maria de Heredia qu’il avait fait le lien entre le Parnasse et le symbolisme. Lui-même fit le lien entre le symbolisme et le Parnasse. En 1895, il notait dans son journal intime : « J’ai subi de grandes influences. Aux premiers jours, Mallarmé m’a […] nettoyé l’esprit ; j’en ai été affiné et ankylosé. Puis j’ai subi les contacts plus vivants d’Heredia. » Cette seconde influence contrebalança la première. Régnier fréquenta les samedis de la rue Balzac avec autan...

  20. Thinking in time an introduction to Henri Bergson

    CERN Document Server

    Guerlac, Suzanne


    "In recent years, we have grown accustomed to philosophical language that is intensely self-conscious and rhetorically thick, often tragic in tone. It is enlivening to read Bergson, who exerts so little rhetorical pressure while exacting such a substantial effort of thought. . . . Bergson's texts teach the reader to let go of entrenched intellectual habits and to begin to think differently—to think in time. . . . Too much and too little have been said about Bergson. Too much, because of the various appropriations of his thought. Too little, because the work itself has not been carefully studied in recent decades."—from Thinking in TimeHenri Bergson (1859–1941), whose philosophical works emphasized motion, time, and change, won the Nobel Prize for Literature in 1927. His work remains influential, particularly in the realms of philosophy, cultural studies, and new media studies. In Thinking in Time, Suzanne Guerlac provides readers with the conceptual and contextual tools necessary for informed appreciati...

  1. James Joyce's Ulysses: The Search for Value

    Directory of Open Access Journals (Sweden)

    Aouda Aljohani


    Full Text Available Two chapters, "Scylla and Charybdis" and "Penelope," in James Joyce's Ulysses are crucial to an understanding of the novel as a whole. "Scylla and Charybdis" stands midway in the novel, the ninth of eighteen chapters, and is designed to serve as a kind of exegesis of the writer's methods and intentions. An analysis of that chapter helps to explain the meaning of the controversial final chapter, "Penelope," and to clarify its thematic and stylistic relation to the text as a whole. Ulysses is the story of a quest, actually of many quests that all coalesce into a single goal: the search for value in a modern world that is somehow diminished and constructed in comparison with the Homeric world where mortals strode the universe in company with gods and goddesses. How, in this dwarfed setting, can men and women redefine heroism in secular humanistic terms relevant to twentieth-century life? Almost by definition a quest narrative culminates in the attainment of the goal or in the potential for its attainment; Joyce's Ulysses affirms this possibility in "Penelope."

  2. James Moores Ball: Ophthalmologist, medical historian, bibliophile. (United States)

    Feibel, Robert M


    James Moores Ball (1862-1929) was an ophthalmologist in St. Louis, Missouri, who excelled as a medical historian and collector of rare and historic books about the history of anatomy. During his lifetime, he was best known as the author of a comprehensive, authoritative, and popular textbook titled Modern Ophthalmology First published in 1904, there were five further editions. Ball was very interested in the history of anatomy and wrote two books on this subject, the first being a biography of Andreas Vesalius, one of the earliest in English, and the second a history of the resurrection men or grave robbers who sold corpses to professors of anatomy and surgery for teaching purposes. His legacy today is the 470 volumes of his personal library, which are now in the Archives and Rare Books department of the Becker Medical Library of the Washington University School of Medicine. These texts are one of their major collections, concentrating on the history of anatomy, beginning with a first edition of Vesalius's De Humani Corporis Fabrica and holding many important and beautiful landmark volumes of anatomical atlases. © The Author(s) 2016.

  3. The James Webb Space Telescope Mission (United States)

    Sonneborn, George


    The James Webb Space Telescope (JWST) is a large aperture, cryogenic, infrared-optimized space observatory under development by NASA for launch in 2014. The European and Canadian Space Agencies are mission partners. JWST will find and study the first galaxies that formed in the early universe, peer through dusty clouds to see AGN environments and stars forming planetary systems at high spatial resolution. The breakthrough capabilities of JWST will enable new studies of star formation and evolution in the Milky Way, including the Galactic Center, nearby galaxies, and the early universe. JWST's instruments are designed to work primarily in the infrared range of 1 - 28 microns, with some capability in the visible. JWST will have a segmented primary mirror, approximately 6.5 meters in diameter, and will be diffraction-limited at wavelength of 2 microns (0.1 arcsec resolution). The JWST observatory will be placed in a L2 orbit by an Ariane 5 launch vehicle provided by ESA. The observatory is designed for a 5-year prime science mission, with propellant for 10 years of science operations. The instruments will provide broad- and narrow-band imaging, coronography, and multi-object and integral-field spectroscopy (spectral resolution of 100 to 3,000) across the 1 - 28 micron wavelength range. Science and mission operations will be conducted from the Space Telescope Science Institute in Baltimore, Maryland.

  4. The "Very Cool" James Webb Space Telescope! (United States)

    Teague, Peter J. B.


    For over twenty years, scientists, engineers, technicians, and other personnel have been working on the next generation space telescope. As a partnership between NASA (National Aeronautics and Space Administration), CSA (Canadian Space Agency), and ESA (European Space Angency), the James Webb Space Telescope will complement the previous research performed by the Hubble by utilizing a larger primary mirror, which will also be optimized for infrared wavelengths. This combination will allow JWST to collect data and take images of light having traveled over 13.7 billion light years. This presentation will focus on the mission, as well as the contamination control challenges during the integration and testing in the NASA Goddard Spacecraft Systems Development and Integration Facility (SSDIF), one of the largest cleanrooms in the world. Additional information will be presented regarding space simulation testing down to a cool 20 degrees Kelvin [-424 degrees Fahrenheit] that will occur at Johnson Space Center in Houston, TX, and more testing and integration to happen at Northrop Grumman Corp., in Redondo Beach, CA. Launch of the JWST is currently scheduled for the spring of 2019 at Ariane Spaceport in French Guiana, South America.

  5. James F. T. Bugental (1915-2008). (United States)

    Schneider, Kirk J; Greening, Tom


    James F. T. Bugental died peacefully at age 92 at his Petaluma, California, home on September 18, 2008. Jim was a leading psychotherapist and a founding father, with Abraham Maslow and others, of humanistic psychology, or the "third force" (in contrast to psychoanalysis and behaviorism). Jim was also the creator, along with Rollo May, of existential-humanistic psychotherapy. Jim was born in Fort Wayne, Indiana, on Christmas Day in 1915. Jim earned his doctorate in 1948 from Ohio State University, where he was influenced by Victor Raimy and George Kelly. After a brief time on the University of California, Los Angeles (UCLA) faculty in psychology, Jim resigned in 1953 to found the first group practice of psychotherapy, Psychological Service Associates, with Alvin Lasko. With Abraham Maslow and others, Jim was a cofounder of the Journal of Humanistic Psychology (JHP) and the Association for Humanistic Psychology in 1961. Jim also wrote many books on the topic of psychotherapy during his lifetime. Jim was a great and bold spirit--his many writings and teachings are cherished today widely, and the field of psychology is much richer for his efforts. 2009 APA, all rights reserved

  6. Watching Time: James Baldwin and Malcolm X

    Directory of Open Access Journals (Sweden)

    Mikko Tuhkanen


    Full Text Available Taking its cue from recent scholarly work on the concept of time in African American literature, this essay argues that, while both James Baldwin and Malcolm X refuse gradualism and insist on “the now” as the moment of civil rights’ fulfillment, Baldwin also remains troubled by the narrowness assumed by a life, politics, or ethics limited to the present moment. In his engagement with Malcolm’s life and legacy—most notably in One Day, When I Was Lost, his screen adaptation of Malcolm’s autobiography—he works toward a temporal mode that would be both punctual and expansive. What he proposes as the operative time of chronoethics is an “untimely now”: he seeks to replace Malcolm’s unyielding punctuality with a different nowness, one that rejects both calls for “patience,” endemic to any politics that rests on the Enlightenment notion of “perfectibility,” and the breathless urgency that prevents the subject from seeing anything beyond the oppressive system he wants overthrown. Both thinkers find the promise of such untimeliness in their sojourns beyond the United States.

  7. W.E. Henry Symposium compendium: The importance of magnetism in physics and material science

    Energy Technology Data Exchange (ETDEWEB)

    Carwell, H.


    This compendium contains papers presented at the W. E. Henry Symposium, The Importance of Magnetism in Physics and Material Science. The one-day symposium was conducted to recognize the achievements of Dr. Warren Elliot Henry as educator, scientist, and inventor in a career spanning almost 70 years. Dr. Henry, who is 88 years old, attended the symposium. Nobel Laureate, Dr. Glenn Seaborg, a friend and colleague for over 40 years, attended the event and shared his personal reminiscences. Dr. Seaborg is Associate Director-At-Large at the Lawrence Berkeley National Laboratory. The Compendium begins with three papers which demonstrate the ongoing importance of magnetism in physics and material science. Other contributions cover the highlights of Dr. Henry`s career as a researcher, educator, and inventor. Colleagues and former students share insights on the impact of Dr. Henry`s research in the field of magnetism, low temperature physics, and solid state physics; his influence on students as an educator; and his character, intellect and ingenuity, and passion for learning and teaching. They share a glimpse of the environment and times that molded him as a man, and the circumstances under which he made his great achievements despite the many challenges he faced.

  8. Directed evolution of the TALE N-terminal domain for recognition of all 5′ bases (United States)

    Lamb, Brian M.; Mercer, Andrew C.; Barbas, Carlos F.


    Transcription activator-like effector (TALE) proteins can be designed to bind virtually any DNA sequence. General guidelines for design of TALE DNA-binding domains suggest that the 5′-most base of the DNA sequence bound by the TALE (the N0 base) should be a thymine. We quantified the N0 requirement by analysis of the activities of TALE transcription factors (TALE-TF), TALE recombinases (TALE-R) and TALE nucleases (TALENs) with each DNA base at this position. In the absence of a 5′ T, we observed decreases in TALE activity up to >1000-fold in TALE-TF activity, up to 100-fold in TALE-R activity and up to 10-fold reduction in TALEN activity compared with target sequences containing a 5′ T. To develop TALE architectures that recognize all possible N0 bases, we used structure-guided library design coupled with TALE-R activity selections to evolve novel TALE N-terminal domains to accommodate any N0 base. A G-selective domain and broadly reactive domains were isolated and characterized. The engineered TALE domains selected in the TALE-R format demonstrated modularity and were active in TALE-TF and TALEN architectures. Evolved N-terminal domains provide effective and unconstrained TALE-based targeting of any DNA sequence as TALE binding proteins and designer enzymes. PMID:23980031

  9. Directed evolution of the TALE N-terminal domain for recognition of all 5' bases. (United States)

    Lamb, Brian M; Mercer, Andrew C; Barbas, Carlos F


    Transcription activator-like effector (TALE) proteins can be designed to bind virtually any DNA sequence. General guidelines for design of TALE DNA-binding domains suggest that the 5'-most base of the DNA sequence bound by the TALE (the N0 base) should be a thymine. We quantified the N0 requirement by analysis of the activities of TALE transcription factors (TALE-TF), TALE recombinases (TALE-R) and TALE nucleases (TALENs) with each DNA base at this position. In the absence of a 5' T, we observed decreases in TALE activity up to >1000-fold in TALE-TF activity, up to 100-fold in TALE-R activity and up to 10-fold reduction in TALEN activity compared with target sequences containing a 5' T. To develop TALE architectures that recognize all possible N0 bases, we used structure-guided library design coupled with TALE-R activity selections to evolve novel TALE N-terminal domains to accommodate any N0 base. A G-selective domain and broadly reactive domains were isolated and characterized. The engineered TALE domains selected in the TALE-R format demonstrated modularity and were active in TALE-TF and TALEN architectures. Evolved N-terminal domains provide effective and unconstrained TALE-based targeting of any DNA sequence as TALE binding proteins and designer enzymes.

  10. Kuidas kõrgemale ohvitserile ettekannet teha / James Stavridis

    Index Scriptorium Estoniae

    Stavridis, James, 1955-


    Endine NATO Euroopa liitlasvägede ülemjuhataja jagab nõuandeid mõjusa ja konstruktiivse ettekande kirjutamiseks ja selle esitlemiseks. Lisatud foto, kus kujutatud James Stavridise autasustamist president Toomas Hendrik Ilvese poolt

  11. NASA 3D Models: James Webb Space Telescope (United States)

    National Aeronautics and Space Administration — The James Webb Space Telescope (JWST) will be a large infrared telescope with a 6.5-meter primary mirror. The project is working to a 2018 launch date. The JWST will...

  12. Young James Madison: His Character and Civic Values. (United States)

    Bennett, William J.


    Examines the life of James Madison, Founding Father and "theoretic statesman." Focuses specifically on Madison's education and character, his friendship with Thomas Jefferson, and his civic legacy: a selfless devotion to republican government and union. (JDH)

  13. TALE proteins search DNA using a rotationally decoupled mechanism. (United States)

    Cuculis, Luke; Abil, Zhanar; Zhao, Huimin; Schroeder, Charles M


    Transcription activator-like effector (TALE) proteins are a class of programmable DNA-binding proteins used extensively for gene editing. Despite recent progress, however, little is known about their sequence search mechanism. Here, we use single-molecule experiments to study TALE search along DNA. Our results show that TALEs utilize a rotationally decoupled mechanism for nonspecific search, despite remaining associated with DNA templates during the search process. Our results suggest that the protein helical structure enables TALEs to adopt a loosely wrapped conformation around DNA templates during nonspecific search, facilitating rapid one-dimensional (1D) diffusion under a range of solution conditions. Furthermore, this model is consistent with a previously reported two-state mechanism for TALE search that allows these proteins to overcome the search speed-stability paradox. Taken together, our results suggest that TALE search is unique among the broad class of sequence-specific DNA-binding proteins and supports efficient 1D search along DNA.

  14. Rapid and accurate synthesis of TALE genes from synthetic oligonucleotides. (United States)

    Wang, Fenghua; Zhang, Hefei; Gao, Jingxia; Chen, Fengjiao; Chen, Sijie; Zhang, Cuizhen; Peng, Gang


    Custom synthesis of transcription activator-like effector (TALE) genes has relied upon plasmid libraries of pre-fabricated TALE-repeat monomers or oligomers. Here we describe a novel synthesis method that directly incorporates annealed synthetic oligonucleotides into the TALE-repeat units. Our approach utilizes iterative sets of oligonucleotides and a translational frame check strategy to ensure the high efficiency and accuracy of TALE-gene synthesis. TALE arrays of more than 20 repeats can be constructed, and the majority of the synthesized constructs have perfect sequences. In addition, this novel oligonucleotide-based method can readily accommodate design changes to the TALE repeats. We demonstrated an increased gene targeting efficiency against a genomic site containing a potentially methylated cytosine by incorporating non-conventional repeat variable di-residue (RVD) sequences.

  15. Teaching the "A" Level Text: "The Wife of Bath's Prologue and Tale." (United States)

    Spraggs, Gillian


    Presents an approach for teaching Chaucer's "Wife of Bath's Prologue and Tale" (from "The Canterbury Tales"). Recommends several reference texts related to the "The Canterbury Tales" and medieval literature in general. (MM)

  16. Telling business stories as fellowship-tales

    DEFF Research Database (Denmark)

    Smith, Robert; Neergaard, Helle


    Purpose – This paper aims to explore the “Fellowship-Tale” as an alternative tale type for narrating entrepreneur stories. The authors illustrate this by telling the Pilgrim business story. It is common for the deeds of men who founded businesses to be narrated as heroic entrepreneur stories...... – The research indicates that “fellowship-tales” provide a viable and credible alternative to the fairy-tale rendition common in entrepreneur and business stories. Research limitations/implications – An obvious limitation is that one merely swaps one narrative framework for another, albeit it offers dissenting...... voices a real choice. Practical implications – This study has the potential to be far reaching because at a practical level, it allows disengaged entrepreneurs and significant others the freedom to exercise their individual and collective voices within a framework of nested stories. Originality...

  17. Genome Editing in Rats Using TALE Nucleases. (United States)

    Tesson, Laurent; Remy, Séverine; Ménoret, Séverine; Usal, Claire; Thinard, Reynald; Savignard, Chloé; De Cian, Anne; Giovannangeli, Carine; Concordet, Jean-Paul; Anegon, Ignacio


    The rat is an important animal model to understand gene function and model human diseases. Since recent years, the development of gene-specific nucleases has become important for generating new rat models of human diseases, to analyze the role of genes and to generate human antibodies. Transcription activator-like (TALE) nucleases efficiently create gene-specific knockout rats and lead to the possibility of gene targeting by homology-directed recombination (HDR) and generating knock-in rats. We describe a detailed protocol for generating knockout and knock-in rats via microinjection of TALE nucleases into fertilized eggs. This technology is an efficient, cost- and time-effective method for creating new rat models.

  18. How Good are Fairy Tales for Adults?

    Directory of Open Access Journals (Sweden)

    Nives Ličen


    Full Text Available Children and adults can learn together in family. Their living together is a valuable experience. Family life can be made agreeable and instructive not only as a result of extensive knowledge, displaying mostly a rational dimension, but also due to emotional inteligence, attitudes and values. Fairy tales can be an incentive for personal development of both children and adults. To adults they offer an opportunity to get to know themselves better, to understand better their thoughts, values, environment. On the other hand, they help them formulate messages they would like to pass on their children. Fairy tales are one of the possible contents for the time family members spend togehter. Moreover, they are a source of entertainment, laughing and they create an excellent atmosphere for good family relationships.

  19. The last half-repeat of transcription activator-like effector (TALE) is dispensable and thereby TALE-based technology can be simplified. (United States)

    Zheng, Chong-Ke; Wang, Chun-Lian; Zhang, Xiao-Ping; Wang, Fu-Jun; Qin, Teng-Fei; Zhao, Kai-Jun


    To activate the expression of host genes that contribute to pathogen growth, pathogenic Xanthomonas bacteria inject their transcription activator-like effectors (TALEs) into plant cells and the TALEs bind to target gene promoters by the central repeat region consisting of near-perfect 34-amino-acid repeats (34-aa repeats). Based on the recognition codes between the 34-aa repeats and the targeted nucleotides, TALE-based technologies, such as designer TALEs (dTALEs) and TALE nucleases (TALENs), have been developed. Amazingly, every natural TALE invariantly has a truncated last half-repeat (LHR) at the end of the 34-aa repeats. Consequently, all the reported dTALEs and TALENs also harbour their LHRs. Here, we show that the LHRs in dTALEs are dispensable for the function of gene activation by both transient expression assays in Nicotiana benthamiana and gene-specific targeting in the rice genome, indicating that TALEs might originate from a single progenitor. In the light of this finding, we demonstrate that dTALEs can be constructed through two simple steps. Moreover, the activation strengths of dTALEs lacking the LHR are comparable with those of dTALEs harbouring the LHR. Our results provide new insights into the origin of natural TALEs, and will facilitate the simplification of the design and assembly of TALE-based tools, such as dTALEs and TALENs, in the near future. © 2014 BSPP AND JOHN WILEY & SONS LTD.


    Directory of Open Access Journals (Sweden)

    - Nazurty


    Full Text Available Tale is the folklore in the form of poem that is sung. This study aims to gain in-depth understanding of the structure of Tale poem in the release of the Kerinci pilgrims. This qualitative study employed content analysis as the method with a structural approach. This study discussed the structure of the Tale poem. The results of the study are Tale poem consists of sampiran phrase, the rhyme/ sound phrase, and content. It composed by ten lines to twenty lines. It has ab ab rhyme according to the sound phrase flanking each line. The sound expression serves as rhyme and rhythm former.

  1. Morality's ugly implications in Oscar Wilde's fairy tales. (United States)

    Jones, Justin T


    In Oscar Wilde's two volumes of fairy tales, "The Happy Prince" and Other Tales (1888) and A House of Pomegranates (1891), many central characters meet with premature death or physical disfigurement after learning a bourgeois moral lesson. In an attempt to explain this unconventional phenomenon in the fairy tale tradition, this essay examines Wilde's stories through the lens of his aesthetic ideology and demonstrates how the superficial morality of the Victorian bourgeoisie corrodes each tale's aesthetic integrity, causing the characters to either deny morality outright, assume the guise of Christian philanthropy, or die as the result of their moral reformation.

  2. James Bay Development Corporation annual report, 1986. Societe de Developpement de la Baie James et entites affiliees rapport annuel, 1986

    Energy Technology Data Exchange (ETDEWEB)


    The James Bay Development Corporation is a paragovernmental body whose objective is to promote the development and exploitation of those natural resources, other than hydroelectric, which are found in the James Bay region of Quebec. It also oversees the administration and infrastructure management in the territory. This report reviews the year's activities of the Corporation and its affiliates involved in tourism, native development, mining, and municipal affairs. Most of the report consists of financial statements.

  3. Restauration de la statue de Henri IV

    Directory of Open Access Journals (Sweden)

    Stéphanie Celle


    Full Text Available Cette intervention de conservation du bronze de la statue de Henri IV était la première depuis sa création en 1818 : on héritait de la surface originale de l’œuvre altérée par les vicissitudes du temps et les événements historiques traversés. Le protocole de conservation se voulait respectueux de cette authenticité de la patine et a cherché à en laisser les marques tout en apportant une réponse pour contrer la corrosion active de l’alliage. C’est en conformité aux principes de conservation établis par Cesare Brandi, qu’ont été définis le nettoyage sélectif des surfaces et l’application de couches protectives sur le bronze. Par ailleurs, le moment du chantier est un moment privilégié pour observer un monument et mieux connaître son histoire particulière. Ce chantier nous a permis de redécouvrir deux ensembles de boîtes déposées dans l’antre du cheval dans des situations parfois surprenantes.This conservation treatment for the bronze statue of Henri IV is the first since its creation in 1818. While the original surface of the work remains, it has been altered by natural and human forces; including the weathering of the material from exposure to the elements and damage caused by historic events. The conservation protocol is respectful of this authenticity of the surface patina and the marks of damage due to historical events, while developing a treatment plan to counter the active corrosion of the alloy. In keeping with the principles of conservation established by Cesare Brandi, the treatment program defines the selective cleaning of the surface and the application of several layers of a protective coating on the bronze. In addition, the conservation project is an opportunity to carefully study a monument to better understand its unique history. This project allowed us to rediscover two sets of boxes placed inside the cavity of the horse; an unxpected discovery.

  4. The personality of Henry Cavendish a great scientist with extraordinary peculiarities

    CERN Document Server

    McCormmach, Russell


    This book explores the 18th century natural philosopher Henry Cavendish, best known for his work in chemistry and physics. It traces aspects of his personality, views and interpretations of him, and explores notions of eccentricity and autism.

  5. NOAA Ship Henry B. Bigelow Underway Meteorological Data, Near Real Time (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Henry B. Bigelow Underway Meteorological Data (Near Real Time, updated daily) are from the Shipboard Automated Meteorological and Oceanographic System...

  6. Hiina kompartei pole NLKP-ga võrreldav / Henri Kaselo

    Index Scriptorium Estoniae

    Kaselo, Henri


    20.-26. novembril Hiinas Pekingis ja sadamalinnas Tianjinis peetud Euroopa ja Aasia noorte kohtumisest, kus Eestit esindasid Keskerakonna noortekogu esimees Henri Kaselo ja Euroopa Noorte Sotsiaaldemokraatide aseesimees ning Toomas Hendrik Ilvese nõunik Rander Läntsi

  7. Strelku vsjo ravno perevedut. No v kakuju storonu? / Henry Posner ; interv. Eteri Kekelidze

    Index Scriptorium Estoniae

    Posner, Henry


    Eesti Raudtee üks erastajaist, RDC juht Henry Posner III meenutab ER erastamist 2001. a., investeeringutest, reeglite muutmisest, Eesti Raudtee müümise põhjustest, Eesti transiidi tulevikust. Diagramm: Eesti Raudtee kasum 1998-2004

  8. 2008 USGS Lidar: Twelve County, Illinois (Grundy, Kane, McHenry only) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This LiDAR data is within Illinois Department of Transportation districts 1 and 3 covering Grundy, Kane and McHenry counties. The data is updated from its original...

  9. The Awkward Academic: Why Judith Reads James in Joyce Carol Oates's "My Warszawa: 1980"

    Directory of Open Access Journals (Sweden)

    Kerry Sutherland


    Full Text Available Joyce Carol Oates’s short story “My Warszawa: 1980” follows the journey of well-respected academician Judith Horne as she travels to and within Poland to participate in an international conference on American culture. She has a vague connection to Poland, with remote family members who were killed in Auschwitz and a Jewish ancestry that can be seen in her features, but she considers these facts unimportant to who she is at the moment. She travels with her lover, who is as remote emotionally as her dead forbears are physically. The emotional connections she makes with the people and land begin to affect her well-ordered and controlled life, including her relationship with him. As they sit side by side on the plane to Poland, he attends to his work as journalist, typewriter on his lap, and Judith gazes at the landscape, an opened book on hers. It is Henry James’s The Awkward Age, unread, chosen by Judith with a logic she cannot recall. Why does Oates give James to Judith, and why does she choose this novel in particular to influence her? Nanda’s story is a warning to Judith, a red flag that unfolds as the younger girl’s ruin proceeds before her eyes, and Judith realizes that the man she loves will never marry her, just as Vanderbank refuses to propose to Nanda. Neither man is comfortable with a woman who is corrupted by knowledge that might undermine his need for authority in the relationship. Nanda understands her position too late, but Judith has time to reflect on her situation, and Oates leaves the story unfinished, with Judith on a plane home with Carl but not definitively resigned to the relationship.

  10. Obituary: Michael James Ledlow, 1964-2004 (United States)

    Puxley, Philip John; Grashuis, Randon M.


    Michael James Ledlow died on 5 June 2004 from a large, unsuspected brain tumor. Since 2000 he had been on the scientific staff of the Gemini Observatory in La Serena, Chile, initially as a Science Fellow and then as a tenure-track astronomer. Michael was born in Bartlesville, Oklahoma on 1 October 1964 to Jerry and Sharon Ledlow. He obtained his Bachelor Degree in astrophysics at the University of Oklahoma in 1987 and attended the University of New Mexico for his graduate work, obtaining his PhD while studying Galaxy Clusters under Frazer Owen in 1994. From 1995-1997 Michael held a postdoctoral position with Jack Burns at New Mexico State University where he used various astronomical facilities including the VLA and Apache Point Observatory to study distant galaxies. From 1998-2000 Michael rejoined the Physics and Astronomy Department at the University of New Mexico where he was a visiting professor until he moved on to Gemini. At the Gemini Observatory, Mike shared in the excitement, hard work and many long days and nights associated with bringing on-line a major new astronomical facility and its instrumentation. Following its commissioning he assisted visiting observers, supported and took data for many more remote users via the queue system, and for each he showed the same care and attention to detail evident in his own research to ensure that all got the best possible data. His research concentrated on the radio and optical properties of galaxy clusters, especially rich Abell clusters such as A2125, on luminous radio galaxies, including the detection of a powerful double radio source in the "wrong sort of galaxy," the spiral system 0313-192, and on EROs (extremely red objects), dusty galaxies barely detectable at optical wavelengths. Michael thoroughly enjoyed living in Chile and enthusiastically immersed himself in the culture of his surroundings. He and his family were actively involved with the International English Spanish Association in La Serena. He had a

  11. Why it was natural for Henri Becquerel to discover natural radioactivity

    International Nuclear Information System (INIS)

    Barquins, M.


    This article presents the scientific saga of the Becquerel family. 4 generations of Becquerel Antoine-Cesar (1788-1878), Edmond (1820-1891), Henri (1852-1906) and Jean (1878-1953) were involved in scientific activities at the highest level. Henri was awarded the Nobel prize of physics (shared with Pierre and Marie Curie) in 1903 for the discovery of radioactivity. The author shows that the discovery of radioactivity was due to talent, family emulation, genetics and chance. (A.C.)

  12. 46 CFR 7.55 - Cape Henry, VA to Cape Fear, NC. (United States)


    ... 46 Shipping 1 2010-10-01 2010-10-01 false Cape Henry, VA to Cape Fear, NC. 7.55 Section 7.55 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.55 Cape Henry, VA to Cape Fear, NC. (a) A line drawn from Rudee Inlet Jetty Light “2” to...

  13. The advantage of using the henry straight line in {gamma} spectrometry (1963); Interet de l'utilisation de la droite de henry en spectrometrie {gamma} (1963)

    Energy Technology Data Exchange (ETDEWEB)

    Jockey, [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires


    The Henry construction is a convenient way to interpret the total absorption peaks in gamma spectrometry by exploiting their statistical significance. It is so possible to determine graphically, and accurately, such values as: - position of the peak - resolution, etc. The main practical applications are considered. (author) [French] La construction de la droite de Henry fournit un moyen commode d'interpreter les pics d'absorption totale en spectrometrie gamma en exploitant leur signification statistique, il est ainsi possible de determiner graphiquement, avec precision, des notions telles que: - position du pic - resolution, etc. Les principales applications pratiques sont envisagees. (auteur)

  14. Henry Beecher's Contributions to the Ethics of Clinical Research. (United States)

    Veatch, Robert M


    In the 1950s and '60s, Henry Beecher pioneered the discussion of the ethics of clinical research, leading eventually to the publication of the famous New England Journal of Medicine article summarizing 22 research studies that Beecher suggests were unethical. Those studies generally showed a pattern of posing serious risks to subjects without anticipated proportional benefit. Beecher famously claimed that the problem was not that researchers were malicious or evil; rather, he claimed the problem was they manifested thoughtlessness or carelessness. He called for more rigorous self-scrutiny rather than public review.This article argues that Beecher's reliance on conscientious investigators is problematic. In particular, it focuses on benefits and harms to the exclusion of other moral criteria. However, both research subjects and public regulators are also concerned about autonomy and the consent requirement, confidentiality, and fairness in subject selection and research design. The movement in the 1970s toward more public scrutiny was critical, even though Beecher was right in holding that it was not "vicious disregard for subject welfare" that explained unethical protocols.

  15. The enigmatic figure of Dr Henry Maudsley (1835-1918). (United States)

    Pantelidou, Maria; Demetriades, Andreas K


    In spite of his contribution to psychiatry in 19th century Britain, Henry Maudsley remains a mysterious figure, a man mostly known for his donation to the London County Council for the building of the Maudsley Hospital and for The Maudsley Annual Lecture created in honour of his benevolence. Besides Sir Aubrey Lewis' article in 1951 and Michael Collie's attempt in 1988 to construct a biographical study on Maudsley, there does not seem to be any current endeavour to tell the story of his life, whereas Trevor Turner's contribution to the 2004 Oxford Dictionary of National Biography gives a somewhat scathing but unattributed account of Maudsley's personality. This essay attempts to explore his contributions to the Medico-Psychological Association (MPA), the current Royal College of Psychiatrists, his editorship of the Journal of Mental Health (currently named the British Journal of Psychiatry), his literary contributions and his vision for a psychiatric hospital. This essay is an attempt to demystify his figure and to explore some of the rumours and criticisms surrounding his name and the reasons why so little has been written about him. It is also a venture to unravel his complex personality and his intricate philosophy. © The Author(s) 2014 Reprints and permissions:

  16. Petroleum possibilities of the James Bay Lowland area: Drilling in the James Bay Lowland

    Energy Technology Data Exchange (ETDEWEB)

    Martison, N W


    Interest in the possible occurrence of petroleum and natural gas in the James Bay lowland arises from the presence there of Palaeozoic sedimentary formations resembling those in south-western Ontario. The first part of this report reviews earlier geologic surveys conducted in the lowland and reports results of field work and drill core studies 1946-51. It describes the area`s topography, climate, stratigraphy and palaeontology (Ordovician to Lower Cretaceous, plus Pleistocene and recent glacial deposits), structural geology, and evidence of petroleum. Lists of fossils and correlations are included. The appendices include a list of fossil locations and drill logs. The second part details the drilling programs carried out in the lowland by the Ontario Dept. of Mines, including detailed logs, as well as drilling carried out by some other organisations.

  17. Obituary: James C. Kemp, 1927-1988 (United States)

    Milone, E. F.


    James C. Kemp was born in Detroit, Michigan on 9 February 1927, and died in Eugene, Oregon, on 29 March 1988. He went to high school in Mexico City and did undergraduate studies at the University of Michigan and University of California at Berkeley. Kemp was an active observational astronomer, having migrated from earlier interests in Slavic languages, in which he majored, electrical engineering, and physics. He obtained a PhD in electrical engineering at Berkeley in 1960 and did post-doctoral work there with Erwin Hahn on spin resonance. He went to the University of Oregon in 1961 and conducted research in magneto-optics, developing, in the process, a piezo-optical birefringence modulator to measure circular polarization. The modulator is described by Tinbergen (1996). Kemp explored new areas as he measured magnetic fields in the sunspots with polarized infrared light, and developed polarimeters and photometers to study the behavior of such astronomical sources as white dwarfs, the relativistic jets of binary SS 433, the x-ray binary Cyg X-1, and the bright eclipsing binaries Algol and e Aurigae on the 61- and, later, 81-cm telescope at the Pine Mountain Observatory, of which Kemp was director until his death from cancer. His measurement of circularly polarization in the continuum light of the white dwarf GJ 742 (Grw +70∘ 8247, Kemp et al. 1970b) was an important discovery, and through his study of Algol (Kemp et al. 1983; Wilson & Liou 1993), he appears to have been the first to discover the limb polarization in eclipsing binaries predicted by Chandrasekhar (1946ab). Although it has taken twenty years for the BAAS to publish his obituary notice, it is somewhat appropriate that his former student, Gary Henson, who provided much of the background for this article, is involved with a polarimetry team to observe and analyze data from e Aurigae, as it approaches ingress of the next primary minimum beginning summer, 2009. The author acknowledges with gratitude the

  18. Transatlanticism and "Natural Sympathy" in Christian Isobel Johnstone’s Clan-Albin: A National Tale (1815

    Directory of Open Access Journals (Sweden)

    Jennifer Marie Van Vliet


    Full Text Available In the decades between Samuel Johnson’s and James Boswell’s tour of the Hebrides and the popular success of Walter Scott’s Waverley novels, a series of synecdochic associations gradually positioned the Highlands as the symbolic cornerstone of British romance and improvement discourses, while Scotland became an integral part of the British Empire. As the popular image of the Highlander had a distinctly martial resonance, transatlantic emigration became a national concern and contributed to the increase in attention paid to improvement in the Highlands. With Clan-Albin: A National Tale (1815, Christian Isobel Johnstone attempts to reconcile the popular imaginings of the Highlands as a pre-modern picturesque microcosm and a “nursery of soldiers” with the sociocultural effects of the Clearances, transforming a culturally and racially distinct Highland hamlet into a thriving pan-British community.

  19. The Encoding of Subjectivity in Chaucer's "The Wife of Bath's Tale" and "The Pardoner's Tale"

    DEFF Research Database (Denmark)

    Klitgård, Ebbe


    This chapter discusses Chaucer's narrative technique in two of The Canterbury Tales and argues that the narrative voice is Chaucer's, and that the subjectivity of the Wife of Bath and the Pardoner should be approached in different ways than through theories of the novel....

  20. Contemporary Christian Tale for Children: Questions of Poetics and Problems

    Directory of Open Access Journals (Sweden)

    Inna V. Shchepacheva


    Full Text Available The article deals with the problems and poetics of Christian fairy tale for children in contemporary Russian literature. The relevance of this issue is motivated by a number of polemic, problematic statements about the form and the content of Christian literature in general, and children's literature in particular. The research reveals features of Christian children’s literature, gives characteristics of its genres and defines the place of the fairy tale as a genre that most satisfies young readers’ needs. The central theme of Christian fairy tales is the theme of realization of existence of God, distinction of good and evil, understanding of sin and punishment. This problem-thematic complex is embodied mainly at the level of composition and character system of fairy tales. During analysis two types of Christian fairy tales are distinguished, generally based on the folklore canon of the fairy tales about animals. In the first type main characters are animals and they help people magically. The predominant didacticism of fairy tales of the first type is realized in schematization of animal images and absence of plot development. The peculiarity of the second type is based on traditional cyclical adventure story and absence of open characters’ convention which is a common feature to parable-allegorical fairy tales.

  1. TALE factors poise promoters for activation by Hox proteins. (United States)

    Choe, Seong-Kyu; Ladam, Franck; Sagerström, Charles G


    Hox proteins form complexes with TALE cofactors from the Pbx and Prep/Meis families to control transcription, but it remains unclear how Hox:TALE complexes function. Examining a Hoxb1b:TALE complex that regulates zebrafish hoxb1a transcription, we find maternally deposited TALE proteins at the hoxb1a promoter already during blastula stages. These TALE factors recruit histone-modifying enzymes to promote an active chromatin profile at the hoxb1a promoter and also recruit RNA polymerase II (RNAPII) and P-TEFb. However, in the presence of TALE factors, RNAPII remains phosphorylated on serine 5 and hoxb1a transcription is inefficient. By gastrula stages, Hoxb1b binds together with TALE factors to the hoxb1a promoter. This triggers P-TEFb-mediated transitioning of RNAPII to the serine 2-phosphorylated form and efficient hoxb1a transcription. We conclude that TALE factors access promoters during early embryogenesis to poise them for activation but that Hox proteins are required to trigger efficient transcription. Copyright © 2014 Elsevier Inc. All rights reserved.

  2. The Indecisive Feminist: Study of Anne Sexton's Revisionist Fairy Tales (United States)

    Mohammed, Nadia Fayidh


    Fairy tales to female writers are major resource for their abundant writings, but for the feminist poets since 1960s, they become essential subject matter to often deal with in their literary production. With the motivation to address the conventional tradition of patriarchal society, and re-address the stereotype females inhabiting these tales,…

  3. Genre Transformation of the Fairy Tale in Contemporary Russian Literature

    Directory of Open Access Journals (Sweden)

    Ekaterina Zueva


    Full Text Available This research is devoted to some peculiarities of structure and semantics of contemporary Russian fairy tale. The analyzed genre model is quite actual in the literature of modern turn of the centuries. It is actualized in the creativity of L. Petrushevskaya, A. Kabakov, B. Akunin, M. Fray, D. Bykov, etc. This is connected with the universality of themes and problems and the dynamics of structure of genre analyzed. Modern literature process suggests the use of various genre forms (including fairy-tale one in the context of realization of game strategies of world construction with the deconstruction principle domination. The usage of the most productive for such kind of research methods (structural-semantical and comparative ones gives grounds for understanding the specifics of realization of deconstruction principle through the variety of forms and meanings. For example, the scheme of “genre memory” is widely used in contemporary fairy tale. If that scheme deals with the sphere of semantics, then structural components are actively deconstructed (e.g. fairy tales by L. Petrushevskaya. If the meaningful fairy tale composition models are actualized, then the semantic component is widely transformed (e.g. Moscow Fairy Tales by A. Kabakov. The most important peculiarity of contemporary fairy tale is the integration of fairy tale, legendary, mythological and literary plots to the one game system. The result of this is on the one hand travestying of the iconic plots, on the other hand achieving the new meanings due to including context mechanisms.

  4. Sustainable development in the Hudson Bay/James Bay bioregion

    International Nuclear Information System (INIS)



    An overview is presented of projects planned for the James Bay/Hudson Bay region, and the expected environmental impacts of these projects. The watershed of James Bay and Hudson Bay covers well over one third of Canada, from southern Alberta to central Ontario to Baffin Island, as well as parts of north Dakota and Minnesota in the U.S.A. Hydroelectric power developments that change the timing and rate of flow of fresh water may cause changes in the nature and duration of ice cover, habitats of marine mammals, fish and migratory birds, currents into and out of Hudson Bay/James Bay, seasonal and annual loads of sediments and nutrients to marine ecosystems, and anadromous fish populations. Hydroelectric projects are proposed for the region by Quebec, Ontario and Manitoba. In January 1992, the Canadian Arctic Resources Committee (CARC), the Environmental Committee of Sanikuluaq, and the Rawson Academy of Arctic Science will launch the Hudson Bay/James Bay Bioregion Program, an independent initiative to apply an ecosystem approach to the region. Two main objectives are to provide a comprehensive assessment of the cumulative impacts of human activities on the marine and freshwater ecosystems of the Hudson Bay/James Bay bioregion, and to foster sustainable development by examining and proposing cooperative processes for decision making among governments, developers, aboriginal peoples and other stakeholders. 1 fig

  5. Obituary: James Gilbert Baker, 1914-2005 (United States)

    Baker, Neal Kenton


    Dr. James Gilbert Baker, renowned astronomer and optical physicist, died 29 June 2005 at his home in Bedford, New Hampshire at the age of 90. Although his scientific interest was astronomy, his extraordinary ability in optical design led to the creation of hundreds of optical systems that supported astronomy, aerial reconnaissance, instant photography (Polaroid SX70 camera), and the US space programs. He was the recipient of numerous awards for his creative work. He was born in Louisville, Kentucky, on 11 November 1914, the fourth child of Jesse B. Baker and Hattie M. Stallard. After graduating from Louisville DuPont Manual High, he went on to attend the University of Louisville majoring in Mathematics. He became very close to an Astronomy Professor, Dr. Moore, and many times used his telescopes to do nightly observations. While at the university, he built mirrors for his own telescopes and helped form the Louisville Astronomical Society in 1933. At the University of Louisville, he also met his future wife, Elizabeth Katherine Breitenstein of Jefferson County, Kentucky. He received his BA in 1935 at the height of the Depression. He began his graduate work in astronomy at the Harvard College Observatory. After his MA (1936), he was appointed a Junior Fellow (1937-1943) in the Prestigious Harvard Society of Fellows. He received his PhD in 1942 from Harvard in rather an unusual fashion, which is worth retelling. During an Astronomy Department dinner, Dr. Harlow Shapley (the director) asked him to give a talk. According to the "Courier-Journal Magazine", "Dr. Shapley stood up and proclaimed an on-the-spot departmental meeting and asked for a vote on recommending Baker for a Ph.D. on the basis of the 'oral exam' he had just finished. The vote was unanimous." It was at Harvard College Observatory during this first stage of his career that he collaborated with Donald H. Menzel, Lawrence H. Aller, and George H. Shortley on a landmark set of papers on the physical processes

  6. TALE-mediated modulation of transcriptional enhancers in vivo. (United States)

    Crocker, Justin; Stern, David L


    We tested whether transcription activator-like effectors (TALEs) could mediate repression and activation of endogenous enhancers in the Drosophila genome. TALE repressors (TALERs) targeting each of the five even-skipped (eve) stripe enhancers generated repression specifically of the focal stripes. TALE activators (TALEAs) targeting the eve promoter or enhancers caused increased expression primarily in cells normally activated by the promoter or targeted enhancer, respectively. This effect supports the view that repression acts in a dominant fashion on transcriptional activators and that the activity state of an enhancer influences TALE binding or the ability of the VP16 domain to enhance transcription. In these assays, the Hairy repression domain did not exhibit previously described long-range transcriptional repression activity. The phenotypic effects of TALER and TALEA expression in larvae and adults are consistent with the observed modulations of eve expression. TALEs thus provide a novel tool for detection and functional modulation of transcriptional enhancers in their native genomic context.

  7. [Development of a Japanese version of the TALE scale]. (United States)

    Ochiai, Tsutomu; Oguchi, Takashi


    The Thinking About Life Experiences (TALE) Scale (Bluck & Alea, 2011) has three subscales that assess the self, social, and directive functions of autobiographical memory. This study constructs a Japanese version of the TALE Scale and examines its reliability and validity. Fifteen items that assess the three functions of autobiographical memory were translated into Japanese. We conducted an online investigation with 600 men and women between 20-59 years of age. In Study 1, exploratory and confirmatory factor analysis identified that the three-factor structure of the Japanese version of the TALE Scale was the same as the original TALE Scale. Sufficient internal consistency of the scale was found, and the construct validity of the scale was supported by correlation analysis. Study 2 confirmed that the test-retest reliabilities of the three subscales were sufficient. Thus, this Japanese version of the TALE Scale is useful to assess autobiographical memory functions in Japan.

  8. Obituary: James N. Kile, 1958-2007 (United States)

    Cliver, Edward W.; Lang, Kenneth R.; Willson, Robert F.


    James N. Kile, of Needham Heights, Massachusetts, died on 17 August 2007, following a brave two-year battle with cancer. One of three children of David R. Kile and Betty Jane Kile, Jim was born in Niagara Falls, New York, on 20 April 1958 and lived in the nearby village of Lewiston before his family settled in Alden, an hour east of Niagara Falls, when Jim was nine. Jim's father worked for American Telephone and Telegraph for 37 years, and his mother was a homemaker. Jim earned his Bachelor's degree in Physics from Rensselaer Polytechnic Institute in 1980, a Master's degree from Northwestern University in 1982, and a Doctorate from Tufts University in 1996 under the direction of Robert Willson. His thesis involved comparison of radio data from the Very Large Array and the Russian RATAN 600 telescope with Yohkoh soft X-ray data, with an emphasis on understanding the relationship between solar noise storms and coronal magnetic fields. While working on his thesis, Jim collaborated with one of us (EWC) at the Air Force Research Laboratory on an investigation of the 154-day periodicity in solar flares. The resulting publication (ApJ 370, 442, 1991) is his most cited work. Jim co-authored four other papers in refereed journals. Jim's professional affiliations included the American Astronomical Society, the American Institute of Aeronautics and Astronautics, the American Geophysical Union, and the Astronomical Society of the Pacific. Jim worked as a contractor in the defense industry from 1982 until the time of his death, settling in the Boston area in the early 1980s. He worked for Calspan Corporation from 1982-1989, the Ultra Corporation from 1989-1994, and the Riverside Research Institute from 1994-2007. He was a highly-respected expert in radar systems, including radar data and systems analysis, systems engineering, and planning support for radar acquisition programs and technology development. The work entailed frequent extended travel to Norway for system testing

  9. Obituary: James Adolph Westphal, 1930-2004 (United States)

    Danielson, G. Edward


    James A. Westphal died September 8, 2004. He had battled a neurological disease related to Alzheimer's for the past year. He was 74. James A. Westphal was born in Dubuque, Iowa, on June 13, 1930. He was raised in Tulsa, Oklahoma, and in Little Rock, Arkansas. Westphal earned his bachelor's degree in physics from the University of Tulsa in 1954, a year after he went to work as geophysical research group leader at Sinclair Research Lab in Tulsa. Westphal first got into the business of scientific instrumentation right after high school, when he did well-logging in Texas and Gulf Coast oil fields. In fact, his work at Sinclair Research Labs involved devising unorthodox methods for oil discovery; one of his discoveries of a new way of processing seismic data first brought him to the attention of Caltech professor Hewitt Dix, who is often considered the father of exploration geophysics. Westphal arrived at Caltech initially on a four-month leave of absence to devise a data processor for Dix, but never left. He discovered that the academic freedom individual professors enjoy was amenable to his own predilections, so he soon began branching out to other areas of scientific investigation at Caltech. Before long, he had teamed up with Bruce Murray to do thermal infrared scans of the moon in order to see if humans could even walk on the lunar surface without sinking into the dusty soil. Westphal and Murray's work showed that rocky areas could be identified with the thermal imaging, which in turn led to the inference that the Apollo astronauts could safely walk on the soil without sinking. Westphal and Murray also teamed up to do the first infrared imaging of Venus and Jupiter. Other projects at Caltech led to Westphal's being hired on permanently by Bob Sharp, who at the time was the geology division chairman. In the following years, Westphal involved himself in novel ways of studying volcanism in Hawaii and Mount St. Helens. He invented a simple and very sensitive tilt meter

  10. Elliptic Tales Curves, Counting, and Number Theory

    CERN Document Server

    Ash, Avner


    Elliptic Tales describes the latest developments in number theory by looking at one of the most exciting unsolved problems in contemporary mathematics--the Birch and Swinnerton-Dyer Conjecture. The Clay Mathematics Institute is offering a prize of 1 million to anyone who can discover a general solution to the problem. In this book, Avner Ash and Robert Gross guide readers through the mathematics they need to understand this captivating problem. The key to the conjecture lies in elliptic curves, which are cubic equations in two variables. These equations may appear simple, yet they arise from

  11. The inauguration of Robert-Bourassa Park at James Bay

    International Nuclear Information System (INIS)

    Valiquette, M.


    Robert Bourassa's contributions to the hydroelectric development at James Bay were acknowledged with the inauguration of a park in the ex-prime minister's name. Phase 1 of the James Bay hydroelectric project constituted the world's biggest construction site, employing more than 180,000 people from beginning to project completion. The James Bay project allowed Hydro-Quebec to gain one of the world's largest electric power utilities and to gain significant competitive edge over its competitors. The Robert Bourassa Park contains a picnic area and a visitor interpretation centre which describes the history of the project. A sequence of 5 signposts summarize the contributions that Robert Bourassa made to the megaproject which cost over $20.6 billion. The complex consists of 65 turbines which produce 15,235 megawatts of electricity. 1 fig

  12. Estudio bibliométrico de la obra de los naturalistas costarricenses Anastasio Alfaro y Henri Pittier en publicaciones periódicas costarricenses entre 1887 y 1946

    Directory of Open Access Journals (Sweden)

    Esteban González Pérez


    Full Text Available Este trabajo analiza la productividad de los naturalistas Anastasio Alfaro y Henri Pittier en un período de 59 años de los cuales entre ambos autores publicaron 316 artículos en diversas fuentes costarricenses. A estos artículos se les aplicaron varios indicadores métricos tales como productividad y colaboración de los autores, zonas de Bradford y vida media. Además se analizaron las palabras claves para identificar las áreas en que publicaron mayoritariamente. Se concluye que estos dos autores se mantuvieron muy activos en sus años de investigación, considerados grandes productores según el indice de productividad de Lotka y con una colaboración muy escasa por parte de otros autores en sus publicaciones. Además, que sus aportes a la memoria histórica de Costa Rica, en las ciencias biológicas son de gran importancia.

  13. The Works of Henry Moseley, 1887-1915 (United States)

    Scerri, Eric


    In 1913 Henry Moseley, an unknown young English physicist published an article in the Philosophical Magazine under the title of ``The High Frequency Spectra of the Elements.'' The 10-page article was to have far reaching implications in both chemistry and physics and helped to resolve a major conundrum in the periodic table of the elements. The talk will briefly examine the life and work of Moseley who died tragically while fighting in the trenches of World War I in 1915. The build-up to the discovery of atomic number took several different avenues including contributions from Rutherford and Barkla. However the more direct motivation for Moseley's work, as he readily acknowledged, were the articles of an unknown Dutch econometrician Anton Van den Broek who attempted to improve on Mendeleev's periodic table. Moseley began as a student of Rutherford at Manchester and took a keen interest in the development of research using X-rays following the work of Roentgen, von Laue and Bragg. Although Rutherford was at first reluctant to enter this new field he soon yielded to young Moseley's request and sent him to Leeds for brief training with Bragg. On returning to Manchester, Moseley devised an ingenious apparatus in which a set of metal samples could be rotated so as to become the target for a beam of electrons in order to measure the frequencies of the emitted K X-rays. The first set of such experiments used nine successive elements in the periodic table, from titanium to zinc. Moseley's now immense fame rests with the results of this study as well as a subsequent one which extended the study into a further 30 elements, in addition to the use that his method was put to by himself as well as subsequent chemists and physicists.

  14. Unheard voices: James Bay II and the women of Kuujjuarapik

    International Nuclear Information System (INIS)

    Hawkes, S.


    The attitudes held by the aboriginal peoples of the James Bay region toward the James Bay II hydroelectric power development are described. These attitudes are communicated primarily through the comments of Innu women. Major concerns with the Great Whale project relate to its impact on country food, mercury contamination, and camps. The entire community of Kuujjuarapik was totally opposed to the Great Whale project. While direct impacts such as mercury contamination or reduced wildlife harvest are the most obvious impacts, indirect impacts relating to cultural damage, increased abuse and alcoholism, and influx of non-native construction workers will also have significant effects, and warrant further study

  15. Unheard voices: James Bay II and the women of Kuujjuarapik

    Energy Technology Data Exchange (ETDEWEB)

    Hawkes, S. (Waterloo Univ., ON (Canada))

    The attitudes held by the aboriginal peoples of the James Bay region toward the James Bay II hydroelectric power development are described. These attitudes are communicated primarily through the comments of Innu women. Major concerns with the Great Whale project relate to its impact on country food, mercury contamination, and camps. The entire community of Kuujjuarapik was totally opposed to the Great Whale project. While direct impacts such as mercury contamination or reduced wildlife harvest are the most obvious impacts, indirect impacts relating to cultural damage, increased abuse and alcoholism, and influx of non-native construction workers will also have significant effects, and warrant further study.

  16. Violence and the Daniel tales in a children's bible | Nel | HTS ...

    African Journals Online (AJOL)

    Children enjoy the tales of Daniel and his three friends, whether told in Sunday school, day school, by parents or grandparents. These tales are cast essentially in violent terms. In this article a specific version of the tales in a children's Bible is analysed to show in what way violence serves as the thread that holds the tales ...

  17. [Hypospadia and infertility of Henry II of France (1519-1559)]. (United States)

    Hatzinger, M; Al-Shajlawi, S; Sohn, M


    Henry II (1519-1559) of France was the second son of Francis I (1494-1547) and Claude de France (1498-1524) born in 1519 in St. Germain-en-Laye. After his older brother's and his father's death in 1547, he was anointed the French king in Reims. In 1533 already, as a 14-year-old boy, for reasons of state, he was married to the same aged Catherine de Medici (1519-1589), as her uncle was Pope Clement VII (1478-1534). The marriage remained childless for 11 years since Henry, due to a distinct hypospadia and a completely sexually inexperienced wife was unable to conceive children with her. His existing liaison to Diane de Poitiers (1499-1566) - a 19-year-older maid of honor of his father Francis I from 1537 until his death - influenced his sexual life immensely.The blame for the childless marriage was placed primarily on his wife, as Henry had become father of an illegitimate daughter with a mistress. Catherine then underwent all possible medical and alchemical procedures to finally give birth to the hoped Dauphin. Ironically, her rival for the favor of her husband, Diane de Poitiers was one of her greatest allies. She made clear that the cause lay with Henry and not with his wife. This was confirmed by the added solid physician Jean Fernel (1497-1558). His treatment of Henry and the simultaneous training of the unexperienced Catherine by Diane de Poitiers led to success.The result was the birth of Francis II (1544-1560) in 1544, the first of 10 children in 12 years. Thus, the dynasty was saved. After the death of Henry in a tragic tournament accident in 1559, three of his sons became kings of France. But the line of Valois remained without further descendants and was continued by Henry IV, the first Bourbon king in 1589.

  18. Quantitative analysis of TALE-DNA interactions suggests polarity effects. (United States)

    Meckler, Joshua F; Bhakta, Mital S; Kim, Moon-Soo; Ovadia, Robert; Habrian, Chris H; Zykovich, Artem; Yu, Abigail; Lockwood, Sarah H; Morbitzer, Robert; Elsäesser, Janett; Lahaye, Thomas; Segal, David J; Baldwin, Enoch P


    Transcription activator-like effectors (TALEs) have revolutionized the field of genome engineering. We present here a systematic assessment of TALE DNA recognition, using quantitative electrophoretic mobility shift assays and reporter gene activation assays. Within TALE proteins, tandem 34-amino acid repeats recognize one base pair each and direct sequence-specific DNA binding through repeat variable di-residues (RVDs). We found that RVD choice can affect affinity by four orders of magnitude, with the relative RVD contribution in the order NG > HD ≈ NN > NI > NK. The NN repeat preferred the base G over A, whereas the NK repeat bound G with 10(3)-fold lower affinity. We compared AvrBs3, a naturally occurring TALE that recognizes its target using some atypical RVD-base combinations, with a designed TALE that precisely matches 'standard' RVDs with the target bases. This comparison revealed unexpected differences in sensitivity to substitutions of the invariant 5'-T. Another surprising observation was that base mismatches at the 5' end of the target site had more disruptive effects on affinity than those at the 3' end, particularly in designed TALEs. These results provide evidence that TALE-DNA recognition exhibits a hitherto un-described polarity effect, in which the N-terminal repeats contribute more to affinity than C-terminal ones.

  19. Successful pregnancy outcome in Swyer-James-Macleod syndrome

    Directory of Open Access Journals (Sweden)

    Chopra Seema


    Full Text Available Swyer-James-MacLeod (SJM syndrome is a chronic, progressive lung disease as a result of infection and bronchial obstruction that ultimately leads to emphysema. It is associated with chronic cough, sputum production and recurrent chest infections and is occasionally seen in women of reproductive age. The radiological finding of unilateral hyperlucent lung is considered synonymous with the disease entity.

  20. James Van Allen and His Namesake NASA Mission (United States)

    Baker, D. N.; Hoxie, V. C.; Jaynes, A.; Kale, A.; Kanekal, S. G.; Li, X.; Reeves, G. D.; Spence, H. E.


    In many ways, James A. Van Allen defined and "invented" modern space research. His example showed the way for government-university partners to pursue basic research that also served important national and international goals. He was a tireless advocate for space exploration and for the role of space science in the spectrum of national priorities.

  1. Keening Woman and Today: James Welch's Early Unpublished Novel (United States)

    Orton, Thomas


    It was most likely in the spring of 1966 that the late American Indian novelist James Welch wrote his first novel, predating his first published fiction by eight years. The titleless, hand-corrected typescript, stored in his Missoula home for many years, is 114 pages long and unfinished. The book is playful and experimental the way warm-ups…

  2. James J. Gallagher: Man in the White Hat (United States)

    Jolly, Jennifer L.; Robinson, Ann


    In classic Western movies, the good guy could be frequently identified by his trademark white Stetson hat, whereas the bad guy always wore black. James J. Gallagher wore many hats during his career that spanned over six decades; he too would be known as the "man in the white hat,"--trusted to do the right thing. From 1967 to 1970,…

  3. Engineering new medicine: an interview with James Collins. (United States)

    Collins, James


    At first glance, the commonality among synthetic gene networks, nerve cell response times and the emergence of antibiotic resistance is obscure. Yet, when speaking with James (Jim) Collins, the relationship becomes clear: all are applications-oriented problems, and all inspire unique approaches from this unusual engineer who is empowered by his freedom to fail.

  4. Groundbreaking Investigator of Creativity: An Interview with James C. Kaufman (United States)

    Henshon, Suzanna E.


    This article presents an interview with James C. Kaufman, an associate professor of psychology at the California State University at San Bernardino, where he directs the Learning Research Institute. Kaufman received his PhD in cognitive psychology from Yale University in 2001. Dr. Kaufman's research broadly focuses on nurturing and encouraging…

  5. 75 FR 13323 - James A. Fitzpatrick Nuclear Power Plant; Exemption (United States)


    ... Power Plant; Exemption 1.0 Background Entergy Nuclear Operations, Inc. (the licensee) is the holder of... nuclear power plants that were licensed before January 1, 1979, satisfy the requirements of 10 CFR Part 50...), as supplemented by letter dated March 30, 2009, ``James A. FitzPatrick Nuclear Power Plant-Response...

  6. 75 FR 16520 - James A. Fitzpatrick Nuclear Power Plant; Exemption (United States)


    ... Power Plant; Exemption 1.0 Background Entergy Nuclear Operations, Inc. (the licensee) is the holder of Facility Operating License No. DPR-59, which authorizes operation of the James A. FitzPatrick Nuclear Power... date for all operating nuclear power plants, but noted that the Commission's regulations provide...

  7. James Madison High: A School at the Crossroads (United States)

    Stroup, John T.; Salmonowicz, Michael J.; Broom, Christopher C.


    This case tells the story of James Madison High School, which became the epicenter of a debate over the future reorganization and control of large secondary schools in the Los Angeles Unified School District (LAUSD). The LAUSD, recently taken over by the newly elected mayor, was fighting for control of this 3,000-student high school with a charter…

  8. James Madison's Practical Ideals for the 1990s. (United States)

    Delattre, Edwin J.

    This paper examines recent behavior of public officials at various levels of government in the United States, finds a systemic failure to meet ethical standards, and concludes that the wisdom of James Madison has much applicability to current times. Given his keen perception of human nature, Madison would not be too surprised at today's poor…

  9. James Madison's "Public" As Interpreter of the Constitution. (United States)

    Dewey, Donald O.

    James Madison's thoughts on various interpretations of the Constitution maintain that public opinion is the ultimate method of legitimizing the document. The Constitution must prevail against mere public opinion, but public opinion may be used to establish the meaning of the Constitution when conflicting interpretations exist. The public good and…




  11. Looking Backward: James Madison University's General Education Reform. (United States)

    Reynolds, Charles W.; Allain, Violet Anselmini; Erwin, T. Dary; Halpern, Linda Cabe; McNallie, Robin; Ross, Martha K.


    Describes the new general education program at James Madison University (Virginia) and the process by which it was developed. Indicates that the program is organized by five broad areas of knowledge that are defined by interdisciplinary clusters of learning objectives, which in turn were developed using input from every academic department on…

  12. The James Madison College Student Handbook, 1970-71. (United States)

    Michigan State Univ., East Lansing. James Madison Coll.

    James Madison College of Michigan State University provides a 4-year, residentially-based program devoted to the study of major social, economic, and political policy problems. It offers 5 fields of concentration: (1) Ethnic and Religious Intergroup Relations Policy Problems; (2) International Relations Policy Problems; (3) Justice, Morality and…

  13. "To Mediate Relevantly": A Response to James Simpson (United States)

    Waters, Alan


    In Waters (2009), it was contended that, because of its ideological orientation, a good deal of applied linguistics for language teaching (ALLT) fails to "mediate relevantly" between academic and practitioner perspectives. James Simpson's rejoinder to my article (Simpson 2009) attempts to refute its claims. However, in my view, it fails to do so,…

  14. James Brown, Sample Culture and the Permanent Distance of Glory

    Directory of Open Access Journals (Sweden)

    Steve Jones


    Full Text Available The James Brown song ‘I’m Real’ (1988 features lyrics regaled from James Brown’s back catalogue, alongside vocal samples extracted from his earlier hits. As one of the most sampled artists of the hip-hop era, James employed sampling in order to reclaim his position as the “Godfather of Soul” and express his disatisfaction at having his work overtly plundered. The central questions I pose here focus on what the choice to sample himself reveals about Brown’s status as a Soul legend, and whether the contemporaneous James could sincerely live up to the mythic status inherent to the message of ‘I’m Real’ given its self-conscious form. This confusion appears to be an extension of Walter Benjamin’s conception of déjà vu as an acoustic effect - ‘the cool tomb of long ago, from the vault of which the present seems to return only as an echo’ (Benjamin cited in Breyley, 2009: 145 - only here the slippage between past and present is quite literal, involving the discordant imbrication of two divergent temporal states. Via a detailed investigation of the song ‘I’m Real‘, I will probe Brown’s playful employment of his own past. His gambit, I will argue, may be read simultaneously as testament to his own glory, and as a signifier that the excesses of egotistic auto-projection were always more distant than they first appeared to be.

  15. The Contributions of James Moir to Physical Chemistry | Loyson ...

    African Journals Online (AJOL)

    James Moir was a pioneering chemist in the early 1900s who played a leading role in various chemical societies in South Africa. Although he was mainly an organic chemist, he was a very good all-round chemist, whose analytical and organic activities have already been covered in this journal. This article examines his ...

  16. Astronaut James Lovell checks body temperature with oral temperature probe (United States)


    Gemini 7 pilot Astronaut James A. Lovell Jr. has temperature check with oral temperature probe attached to his space suit during final preflight preparations for the Gemini 7 space mission. The temperature probe allows doctors to monitor astronauts body temperature at any time during the mission.

  17. Between Attraction and Narration: Early Film Adaptations of Fairy Tales

    Directory of Open Access Journals (Sweden)

    Peter Verstraten


    Full Text Available Adaptations of fairy tales were particularly popular in the years of early cinema. In the period preceding the year 1903 films consisted of a series of animated tableaux since filmmakers had difficulties in telling a coherent story. Allusions to a well‐known tale could then function as a guide for the spectator. At the same time, filmmakers were fond of experimenting with cinematic tricks, such as stop‐motion techniques and superimpositions. The fairy tale offers a legitimate backdrop for these tricks and these film adaptations even display an excess of the marvelous at the cost of the actual story itself.

  18. Environmental Assessment on the leasing of the Strategic Petroleum Reserve, St. James Terminal, St. James Parish, Louisiana

    Energy Technology Data Exchange (ETDEWEB)



    The US Department of Energy (DOE) proposes to lease the Strategic Petroleum Reserve`s (SPR) St. James Terminal to private industry. The St. James Terminal consists of six storage tanks, a pumping station, two maine docks and ancillary facilities. DOE believes that the St. James Terminal presents an opportunity to establish a government- industry arrangement that could more effectively use this asset to serve the nations`s oil distribution needs, reduce the operational cost of the SPR, and provide a source of revenue for the Government. DOE solicited interest in leasing its distribution facilities in a notice published March 16, 1994. In response, industry has expressed interest in leasing the St. James Terminal, as well as several DOE pipelines, to enhance the operation of its own facilities or to avoid having to construct new ones. Under such a lease, industry use would be subordinate to DOE use in the event of a national energy emergency. This Environmental Assessment describes the proposed leasing operation, its alternatives, and potential environmental impacts. Based on this analyses, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) OF 1969 and has issued the Finding of No Significant Impact (FONSI).

  19. Environmental Assessment on the leasing of the Strategic Petroleum Reserve, St. James Terminal, St. James Parish, Louisiana

    International Nuclear Information System (INIS)


    The US Department of Energy (DOE) proposes to lease the Strategic Petroleum Reserve's (SPR) St. James Terminal to private industry. The St. James Terminal consists of six storage tanks, a pumping station, two maine docks and ancillary facilities. DOE believes that the St. James Terminal presents an opportunity to establish a government- industry arrangement that could more effectively use this asset to serve the nations's oil distribution needs, reduce the operational cost of the SPR, and provide a source of revenue for the Government. DOE solicited interest in leasing its distribution facilities in a notice published March 16, 1994. In response, industry has expressed interest in leasing the St. James Terminal, as well as several DOE pipelines, to enhance the operation of its own facilities or to avoid having to construct new ones. Under such a lease, industry use would be subordinate to DOE use in the event of a national energy emergency. This Environmental Assessment describes the proposed leasing operation, its alternatives, and potential environmental impacts. Based on this analyses, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) OF 1969 and has issued the Finding of No Significant Impact (FONSI)

  20. Once upon Anion: A Tale of Photodetachment (United States)

    Lineberger, W. Carl


    This contribution is very much a personal history of a journey through the wonderful world of anion chemistry, and a tale of how advances in laser technologies, theoretical methods, and computational capabilities continuously enabled advances in our understanding. It is a story of the excitement and joy that come from the opportunity to add to the fabric of science, and to do so by working as a group of excited explorers with common goals. The participants in this journey include me, my students and postdoctoral associates, my collaborators, and our many generous colleagues. It all happened, in the words of the Beatles, “with a little help from my friends.” Actually, it was so much more than a little help!

  1. Henry constants in polymer solutions with the van der Waals equation of state

    DEFF Research Database (Denmark)

    Bithas, Sotiris; Kalospiros, Nikolaos; Kontogeorgis, Georgios


    parameter is satisfactory, with typical errors within the experimental uncertainty and comparable to those with the more complex Perturbed Hard Chain Theory-based equations of state with the same number of adjustable parameters. A predictive scheme for calculating Henry constants is also presented, which...... is a corresponding-states correlation for a dimensionless Henry constant defined based on the van der Waals equation of state. Satisfactory results-often close to the ones from the one-parameter correlation-are obtained for all systems investigated in this work. Compared with literature models that have been applied...

  2. Copper-Mediated Reactions of Nitriles with Nitromethanes: Aza-Henry Reactions and Nitrile Hydrations. (United States)

    Kuwabara, Jun; Sawada, Yoshiharu; Yoshimatsu, Mitsuhiro


    In this study, the first aza-Henry reaction of nitriles with nitromethane in a CuI/Cs 2 CO 3 /DBU system is described. The process was conveniently and directly used for the synthesis of β-aminonitroalkenes 2a-x and tolerated aryl-, alkyl-, hetaryl-, alkenyl-, and alkynylnitriles. The resulting aminonitroalkenes 2 could be successfully transformed to the corresponding 2-nitroacetophenones, 2-amino-1-halonitroalkenes, 2-alkylaminonitroalkenes, or 3-nitropyridines. In the presence of H 2 O, the aza-Henry reaction turned the reaction path to the nitrile hydration to exclusively yield the amides 3a-s.

  3. Taxing junk food: applying the logic of the Henry tax review to food. (United States)

    Bond, Molly E; Williams, Michael J; Crammond, Brad; Loff, Bebe


    The recent review of taxation in Australia - the Henry tax review - has recommended that the federal government increase the taxes already levied on tobacco and alcohol. Tobacco and alcohol taxes are put forward as the best way of reducing the social harms caused by the use and misuse of these substances. Junk foods have the same pattern of misuse and the same social costs as tobacco and alcohol. The Henry tax review rejects the idea of taxing fatty foods, and to date the government has not implemented a tax on junk food. We propose that a tax on junk food be implemented as a tool to reduce consumption and address the obesity epidemic.

  4. Using Jack Tales in a Second Grade Class. (United States)

    Brown, Doris


    Describes a project in which Kentucky second grades developed puppet shows and photography activities based on traditional Appalachian oral tales. Discusses student progress in language arts skills, creativity, use of audiovisual equipment, and group cooperation. (SV)


    African Journals Online (AJOL)


    others as being philosophers and scientists in one single swoop. The ... methodic forum. .... universe as its object and discovery of the quiddity of phenomena as ... 3. The Politics of Global Warming and the Implications of Tales of Science.

  6. 'The crocodile's wife' – a tale of transformations | Wendland ...

    African Journals Online (AJOL)

    nthano) about a magical personal transformation, as this metaphorical story has been subsequently adapted for a dramatised radio representation. The artistic transformer, Julius Chongo, took a recording of the original village tale and used its ...

  7. Another Tale of Two Cities: Contestation of Globalization in Odia ...

    African Journals Online (AJOL)

    Another Tale of Two Cities: Contestation of Globalization in Odia Ofeimun's ... state, in all its social, economic and cultural aspirations, coupled with its trappings of ... as a result of such issues as capitalism, race, nationality, identity and nativity.

  8. 78 FR 34428 - Missouri Central Railroad Company-Abandonment Exemption-in Cass, Henry, Johnson, and Pettis... (United States)


    ... No. AB 1070; (Sub-No. 1X)] Missouri Central Railroad Company--Abandonment Exemption--in Cass, Henry, Johnson, and Pettis Counties, MO; Central Midland Railway Company--Discontinuance of Service Exemption--in Cass, Henry, Johnson, and Pettis Counties, MO Missouri Central Railroad Company (MCRR) and Central...

  9. Henri Fayol’un Yönetim Düşüncesi Üzerine Notlar(Notes on Managerial Thought of Henry Fayol)


    Ramazan ŞENGÜL


    Henri Fayol, developed a managerial approach which is a perfect guide for both private and public sectors through focusing systematically upon managerial process. A major advantage of Fayol in creating a general managerial doctrine was his pratician side. His managerial thought which was developed in the early 20th century lasted up to our times. The distinguished characteristic of Fayol’s thought was studying the administrative reality through separating it into its functions, in that it hel...

  10. Intertextuality in the Tales of Rabbi Nahman of Bratslav

    DEFF Research Database (Denmark)

    Schleicher, Marianne

    not yet been undertaken. As the first comprehensive scholarly work on the whole selection of tales and contrary to previous scholarship, this book does not reduce the tales to biographical expressions of Nahman's tormented soul and messianic aspirations. Instead, it treats them as religious literature...... where the concept of "intertextuality" is considered essential to explain how Nahman defines his theology of redemption and invites his listeners and readers to appropriate his religious world-view....

  11. Die Another Day, James Bond's smoking over six decades. (United States)

    Wilson, Nick; Tucker, Anne


    We aimed to examine smoking-related content in all 24 James Bond movies in the Eon Productions series from 1962 to 2015. There were favourable downward trends for any smoking by James Bond (p=0.015 for trend), and for tobacco-related spy-gadgetry (p=0.009). Around 20% of Bond's 60 sexual partners smoked in each decade, and most recently in 2012. There were regular mentions of smoking risks to health (starting from 1967) and product placement of branded packs was present in two movies. Overall, the persisting smoking content remains problematic from a public health perspective, especially given the popularity of this movie series. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to

  12. James Madison and a Shift in Precipitation Seasonality (United States)

    Druckenbrod, D. L.; Mann, M. E.; Stahle, D. W.; Cleaveland, M. K.; Therrell, M. D.; Shugart, H. H.


    An eighteen-year meteorological diary and tree ring data from James Madison's Montpelier plantation provide a consistent reconstruction of early summer and prior fall rainfall for the 18th Century Virginia piedmont. The Madison meteorological diary suggests a seasonal shift in monthly rainfall towards an earlier wet season relative to 20th Century norms. Furthermore, dendroclimatic reconstructions of early summer and prior fall rainfall reflect this shift in the seasonality of summer rainfall. The most pronounced early summer drought during the Madison diary period is presented as a case study. This 1792 drought occurs during one of the strongest El Niño events on record and is highlighted in the correspondence of James Madison.

  13. Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors. (United States)

    Thakore, Pratiksha I; Gersbach, Charles A


    Transcription activator-like effectors (TALEs) are modular DNA-binding proteins that can be fused to a variety of effector domains to regulate the epigenome. Nucleotide recognition by TALE monomers follows a simple cipher, making this a powerful and versatile method to activate or repress gene expression. Described here are methods to design, assemble, and test TALE transcription factors (TALE-TFs) for control of endogenous gene expression. In this protocol, TALE arrays are constructed by Golden Gate cloning and tested for activity by transfection and quantitative RT-PCR. These methods for engineering TALE-TFs are useful for studies in reverse genetics and genomics, synthetic biology, and gene therapy.

  14. Solar System Observations with the James Webb Space Telescope


    Norwood, James; Hammel, Heidi; Milam, Stefanie; Stansberry, John; Lunine, Jonathan; Chanover, Nancy; Hines, Dean; Sonneborn, George; Tiscareno, Matthew; Brown, Michael; Ferruit, Pierre


    The James Webb Space Telescope will enable a wealth of new scientific investigations in the near- and mid-infrared, with sensitivity and spatial/spectral resolution greatly surpassing its predecessors. In this paper, we focus upon Solar System science facilitated by JWST, discussing the most current information available concerning JWST instrument properties and observing techniques relevant to planetary science. We also present numerous example observing scenarios for a wide variety of Solar...

  15. La racionalidad imperialista en la monumental obra de James Mill

    Directory of Open Access Journals (Sweden)

    Homero Cuevas


    Full Text Available Este ensayo, parte de un trabajo más extenso sobre la dominación internacional en la economía mundial, revisa los procesos más relevantes para el análisis teórico tomando como referencia La historia de la India británica de James Mill, obra que es un hito en este campo y es la base de todas las teorías posteriores

  16. Theoretical Insight of Physical Adsorption for a Single Component Adsorbent + Adsorbate System: II. The Henry Region

    KAUST Repository

    Chakraborty, Anutosh; Saha, Bidyut Baran; Ng, Kim Choon; Koyama, Shigeru; Srinivasan, Kandadai


    evaluated and compared with experimental data. It is found that the adsorbents with higher specific surface areas tend to possess lower heat of adsorption (ΔH°) at the Henry regime. In this paper, we have established the definitive relation between Ai and ΔH

  17. Paul Henry Latimer (1925-2011): discoverer of selective scattering in photosynthetic systems. (United States)

    Latimer, Margaret Gwyn; Bannister, Thomas T; Govindjee


    We provide here a brief tribute to Paul Henry Latimer (November 25, 1925 to October 1, 2011), a dedicated biological physicist, discoverer of selective scattering in biological systems, a wonderful teacher, husband, and father. We provide here a glimpse of his personal and professional life, including reminiscences from F. Dudley Bryant, Dan A. Cross, Bobby E. Pyle, Bryan L. Seiber, and Bruce A. Seiber.

  18. Visualizing the Life and Legacy of Henry VIII: Guiding Students with Eight Types of Graphic Organizers (United States)

    Gallavan, Nancy P.; Kottler, Ellen


    Delving into the life and legacy of Henry VIII is both complex and captivating. People seem compelled to learn more abut his critical contributions and controversial conduct that range from the significant to the scandalous. Reflecting on the history of the world would be incomplete without investigating the events and escapades associated with…

  19. Henri Wallon's Theory of Early Child Development: The Role of Emotions. (United States)

    Van der Veer, Rene


    Discusses the stage theory of early child development of French theorist Henri Wallon. Describes Wallon's efforts (in contrast to contemporary Piaget) to describe emotional development and the role emotions play in establishing the child-caregiver bond. Argues that Wallon's theory is unique in its focus, influenced theorists such as Vygotsky, and…

  20. The Heuristic Method, Precursor of Guided Inquiry: Henry Armstrong and British Girls' Schools, 1890-1920 (United States)

    Rayner-Canham, Geoff; Rayner-Canham, Marelene


    Though guided-inquiry learning, discovery learning, student-centered learning, and problem-based learning are commonly believed to be recent new approaches to the teaching of chemistry, in fact, the concept dates back to the late 19th century. Here, we will show that it was the British chemist, Henry Armstrong, who pioneered this technique,…

  1. The Royal Entries of Henry VI in a London Civic Manuscript

    DEFF Research Database (Denmark)

    Bourassa, Kristin


    London Metropolitan Archives, MS Letter Book K, contains descriptions of Henry VI’s royal entries into both Paris (1431) and London (1432). Their placement one after the other in a London Letter Book was likely the work of the city’s common clerk, John Carpenter, who was the author of the descrip...

  2. 76 FR 63906 - Henry Gordy International, Inc., Provisional Acceptance of a Settlement Agreement and Order (United States)


    ... International, Inc., containing a civil penalty of $1,100,000.00. DATES: Any interested person may ask the... report of a death involving a Target Set on or about May 1, 2006, after an 8-year-old boy choked on a dart and died on March 9, 2006. 8. In response to the death reported on or about May 1, 2006, Henry...

  3. The Snake Charmer(ess intermedia dialogue between Henri Rousseau's Painting and Sylvia Plath's poetry

    Directory of Open Access Journals (Sweden)

    Milovanov Dajana


    Full Text Available The paper examines possible interpretations of poetry and poetic image analysing the dialogue between the arts of literature and painting. The paper studies the poet Sylvia Plath's referencing Henri Rousseau's painting The Snake Charmer in her poem 'Snakecharmer'. What is analysed is the creative superstructure based upon nonliterary reference, as well as the visual elements attained through two diverse artistic media.

  4. Ernest Henry Starling: the history of cardiovascular endocrinology and the continuous need for developing animal models

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik Sahl


    The English physiologist, Ernest Henry Starling (1866–1927) (Fig. 1) in 1896, provided a quantitative explanation of the transcapillary transport of fluid. Six years later, he discovered the first hormone and introduced the concept of hormones in 1905, and at the time of the First World War, he f......’s achievements in cardiovascular physiology and endocrinology....

  5. W.E. Henry Symposium Compendium, Lawrence Berkeley National Laboratory, September 19, 1997 (United States)


    Society • Philosophical Society of Washington • Washington Academy of Sciences • New York Academy of Sciences • Institut International du Froid ...Powered Magnets" Reports of NRL Progress, Nov. 1958. 29. Henry, Warren E. "Aimantation dans les champs forts et approche a la saturation absolue du

  6. Enter the Madcap Prince of Wales: Students Directing "Henry IV, Part I." (United States)

    Earthman, Elise Ann


    Argues that William Shakespeare's "Henry IV, Part I" is an appropriate and useful text for secondary English classrooms. Shows how the play lends itself to performance-based instruction. Outlines ways of accomplishing student engagement, using film versions, and assigning written work. (HB)

  7. Community Arts Programs: Cohesion and Difference Case Studies. Henry Street Settlement and El Museo del Barrio (United States)

    Kiebert-Gruen, Cathleen


    A comparative case study of two cultural institutions, Henry Street Settlement and El Museo del Barrio, founded almost eighty years apart, were involved in social justice causes and community arts. Although both of these institutions participated in the political activism of their time, they also demonstrated an important adaptability. They were…

  8. Pornografia e transgressão na obra literária de Henry Miller

    Directory of Open Access Journals (Sweden)

    Raquel Catunda Pereira


    Full Text Available The North American writer Henry Miller was marginalized by literary critics since the first publications of his works in the 40s. Accused of being a pornographic text, the book Tropic of Cancer (1934 was forbidden in many countries. This article aims to analyze the obscene in Henry Miller’s work to prove that, beyond the erotic intention, Miller’s books are an expression of freedom and rejection of moral standards. In order to achieve our goal, we will use as theoretical basis the articles Criticismo e sexualidade: uma leitura de Tropico of Capricorn de Henry Miller, by Flávia Andréa Rodrigues Benfatt, and Literatura marginal americana: do épico confessional ao niilismo erótico, by Lainister de Oliveira. The texts mentioned above grant us the argumentation necessary to the analysis of pornographic discourse in Henry Miller’s literary works as the author’s aesthetics choice of taking himself as a transgressor in a decadent society.

  9. Henry Evelyn Bliss--The Other Immortal, or a Prophet without Honour? (United States)

    Broughton, Vanda


    The paper takes a retrospective look at the work of Henry Evelyn Bliss, classificationist theorist and author of the "Bibliographic Classification". Major features of his writings and philosophy are examined and evaluated for the originality of their contribution to the corpus of knowledge in the discipline. Reactions to Bliss's work are analysed,…

  10. Mounting a Curricular Revolution: An Interview with Henry Louis Gates, Jr. (United States)

    von Zastrow, Claus


    This article presents an interview with Henry Louis Gates, Jr., Harvard professor and cultural critic who has captured 25 million viewers with his PBS documentary series, African American Lives (WNET). Using genealogical research and DNA science, Gates traces the family history of 19 famous African Americans. What results is a rich and moving…

  11. The 'Overly-Broad' Selden Patent, Henry Ford and Development in the Early US Automobile Industry

    DEFF Research Database (Denmark)

    Howells, John; Katznelson, Ron D

    of the Selden patent claims. We use new primary sources to show how Henry Ford and others engaged in what today is called “Freedom to Operate” patent analysis when it most mattered commercially. We show that Ford correctly anticipated that a future court adjudication of the Selden patent claims would...

  12. Fin-de-Siecle Advances in Neuroeducation: Henry Herbert Donaldson and Reuben Post Halleck (United States)

    Theodoridou, Zoe D.; Triarhou, Lazaros C.


    This article focuses on two early attempts at bridging neuroscience and education, made by Henry Herbert Donaldson (1857-1938), a neurologist, and Reuben Post Halleck (1859-1936), an educator. Their works, respectively entitled "The Growth of the Brain: A Study of the Nervous System in Relation to Education" (1895) and "The Education of the…

  13. Engineering customized TALE nucleases (TALENs) and TALE transcription factors by fast ligation-based automatable solid-phase high-throughput (FLASH) assembly. (United States)

    Reyon, Deepak; Maeder, Morgan L; Khayter, Cyd; Tsai, Shengdar Q; Foley, Jonathan E; Sander, Jeffry D; Joung, J Keith


    Customized DNA-binding domains made using transcription activator-like effector (TALE) repeats are rapidly growing in importance as widely applicable research tools. TALE nucleases (TALENs), composed of an engineered array of TALE repeats fused to the FokI nuclease domain, have been used successfully for directed genome editing in various organisms and cell types. TALE transcription factors (TALE-TFs), consisting of engineered TALE repeat arrays linked to a transcriptional regulatory domain, have been used to up- or downregulate expression of endogenous genes in human cells and plants. This unit describes a detailed protocol for the recently described fast ligation-based automatable solid-phase high-throughput (FLASH) assembly method. FLASH enables automated high-throughput construction of engineered TALE repeats using an automated liquid handling robot or manually using a multichannel pipet. Using the automated approach, a single researcher can construct up to 96 DNA fragments encoding TALE repeat arrays of various lengths in a single day, and then clone these to construct sequence-verified TALEN or TALE-TF expression plasmids in a week or less. Plasmids required for FLASH are available by request from the Joung lab ( This unit also describes improvements to the Zinc Finger and TALE Targeter (ZiFiT Targeter) web server ( that facilitate the design and construction of FLASH TALE repeat arrays in high throughput. © 2013 by John Wiley & Sons, Inc.

  14. A Farey tale for N = 4 dyons

    International Nuclear Information System (INIS)

    Murthy, Sameer; Pioline, Boris


    We study exponentially suppressed contributions to the degeneracies of extremal black holes. Within Sen's quantum entropy function framework and focusing on extremal black holes with an intermediate AdS 3 region, we identify an infinite family of semi-classical AdS 2 geometries which can contribute effects of order exp(S 0 /c), where S 0 is the Bekenstein-Hawking-Wald entropy and c is an integer greater than one. These solutions lift to the extremal limit of the SL(2,Z) family of BTZ black holes familiar from the 'black hole Farey tail'. We test this understanding in N = 4 string vacua, where exact dyon degeneracies are known to be given by Fourier coefficients of Siegel modular forms. We relate the sum over poles in the Siegel upper half plane to the Farey tail expansion, and derive a 'Farey tale' expansion for the dyon partition function. Mathematically, this provides a (formal) lift from Hilbert modular forms to Siegel modular forms with a pole at the diagonal divisor.

  15. Policy Pathways: A Tale of Renewed Cities

    Energy Technology Data Exchange (ETDEWEB)



    Transport currently accounts for half of global oil consumption and nearly 20% of world energy use, of which approximately 40% is used in urban transport alone. The IEA expects urban transport energy consumption to double by 2050, despite ongoing vehicle technology and fuel-economy improvements. While increased mobility brings many benefits, the staggering rate of this increase creates new challenges. Urgent energy-efficiency policy attention will be needed to mitigate associated negative noise, air pollution, congestion, climate and economic impacts, all of which can cost countries billions of dollars per year. This report highlights lessons learned and examples of good practice from countries with experience implementing a wide range of measures to improve energy efficiency in urban transport systems. Part of the IEA Policy Pathway series, A Tale of Renewed Cities sets out key steps in planning, implementation, monitoring and evaluation to achieve improved energy efficiency in urban transport systems. The Policy Pathway series aims to help policy makers implement the IEA 25 Energy Efficiency Policy Recommendations.

  16. Direct observation of TALE protein dynamics reveals a two-state search mechanism. (United States)

    Cuculis, Luke; Abil, Zhanar; Zhao, Huimin; Schroeder, Charles M


    Transcription activator-like effector (TALE) proteins are a class of programmable DNA-binding proteins for which the fundamental mechanisms governing the search process are not fully understood. Here we use single-molecule techniques to directly observe TALE search dynamics along DNA templates. We find that TALE proteins are capable of rapid diffusion along DNA using a combination of sliding and hopping behaviour, which suggests that the TALE search process is governed in part by facilitated diffusion. We also observe that TALE proteins exhibit two distinct modes of action during the search process-a search state and a recognition state-facilitated by different subdomains in monomeric TALE proteins. Using TALE truncation mutants, we further demonstrate that the N-terminal region of TALEs is required for the initial non-specific binding and subsequent rapid search along DNA, whereas the central repeat domain is required for transitioning into the site-specific recognition state.

  17. 'Who is wise and understanding among you' (James 3: 13? An analysis of wisdom, eschatology and apocalypticism in the epistle of James

    Directory of Open Access Journals (Sweden)

    Patrick J. Hartin


    Full Text Available Three questions form the basis of this analysis of the relationship of the Epistle of James to the traditions of wisdom, eschatology and apocalypticism. What kind of traditions are involved in James? What is the world view of James? What audience or community is presupposed by this writing? Foremost is the connection that James demonstrates to the wisdom tradition evident in the Old Testament and extratestamental literature. In particular two types of wisdom tradition are noted in James: practical wisdom advice as expressed in short sayings, wisdom instructions and admonitions and reflection on the nature of wisdom (1:5-8; 2:1-7; and 3:13-18 as coming from God. Finally, the question of how much apocalyptic symbolism is evident in the eschatological world view of the epistle is addressed.

  18. Desperate remedies: a Gothic tale of madness and modern medicine. (United States)

    Scull, A


    The theory that many diseases were produced by focal infection or chronic sepsis enjoyed a brief vogue in general medicine in the first quarter of the twentieth century. This paper explores its practical applications in psychiatry, which extended well into the 1930s. The analysis focuses particularly closely on the activities of Henry A. Cotton at the Trenton State Hospital in New Jersey.

  19. Conformational elasticity can facilitate TALE-DNA recognition. (United States)

    Lei, Hongxing; Sun, Jiya; Baldwin, Enoch P; Segal, David J; Duan, Yong


    Sequence-programmable transcription activator-like effector (TALE) proteins have emerged as a highly efficient tool for genome engineering. Recent crystal structures depict a transition between an open unbound solenoid and more compact DNA-bound solenoid formed by the 34 amino acid repeats. How TALEs switch conformation between these two forms without substantial energetic compensation, and how the repeat-variable di-residues (RVDs) discriminate between the cognate base and other bases still remain unclear. Computational analysis on these two aspects of TALE-DNA interaction mechanism has been conducted in order to achieve a better understanding of the energetics. High elasticity was observed in the molecular dynamics simulations of DNA-free TALE structure that started from the bound conformation where it sampled a wide range of conformations including the experimentally determined apo and bound conformations. This elastic feature was also observed in the simulations starting from the apo form which suggests low free energy barrier between the two conformations and small compensation required upon binding. To analyze binding specificity, we performed free energy calculations of various combinations of RVDs and bases using Poisson-Boltzmann surface area (PBSA) and other approaches. The PBSA calculations indicated that the native RVD-base structures had lower binding free energy than mismatched structures for most of the RVDs examined. Our theoretical analyses provided new insight on the dynamics and energetics of TALE-DNA binding mechanism. © 2014 Elsevier Inc. All rights reserved.

  20. Chimeric TALE recombinases with programmable DNA sequence specificity. (United States)

    Mercer, Andrew C; Gaj, Thomas; Fuller, Roberta P; Barbas, Carlos F


    Site-specific recombinases are powerful tools for genome engineering. Hyperactivated variants of the resolvase/invertase family of serine recombinases function without accessory factors, and thus can be re-targeted to sequences of interest by replacing native DNA-binding domains (DBDs) with engineered zinc-finger proteins (ZFPs). However, imperfect modularity with particular domains, lack of high-affinity binding to all DNA triplets, and difficulty in construction has hindered the widespread adoption of ZFPs in unspecialized laboratories. The discovery of a novel type of DBD in transcription activator-like effector (TALE) proteins from Xanthomonas provides an alternative to ZFPs. Here we describe chimeric TALE recombinases (TALERs): engineered fusions between a hyperactivated catalytic domain from the DNA invertase Gin and an optimized TALE architecture. We use a library of incrementally truncated TALE variants to identify TALER fusions that modify DNA with efficiency and specificity comparable to zinc-finger recombinases in bacterial cells. We also show that TALERs recombine DNA in mammalian cells. The TALER architecture described herein provides a platform for insertion of customized TALE domains, thus significantly expanding the targeting capacity of engineered recombinases and their potential applications in biotechnology and medicine.

  1. A classic fairy tale in the first triennial of the elementary school and the family literacy


    Lukaček, Alenka


    A classic fairy tale by a known author is modelled on a folk fairy tale as regards the structure, themes and motifs; however, it mostly differs from it in poetics which gives the fairy tale the character of the author’s narrative” (Haramija, 2012: 17). Fairy tales have been researched since the 19th century and they have been analysed according to numerous theories: folk theory, structuralism theory, literary theory, psychoanalytic theory, sociological theory, feminist theory, and poststructu...

  2. Writing and Retelling Multiple Ethnographic Tales of a Soup Kitchen for the Homeless. (United States)

    Miller, Dana L.; Creswell, John W.; Olander, Lisa

    An ethnographic study narrated three tales about a soup kitchen for the homeless and the near-homeless. To provide a cultural, ethnographic analysis, and share fieldwork experiences the study began with realist and confessional tales. These two tales emerged from the initial writing and presenting of the soup kitchen ethnography to qualitative…

  3. Live visualization of genomic loci with BiFC-TALE. (United States)

    Hu, Huan; Zhang, Hongmin; Wang, Sheng; Ding, Miao; An, Hui; Hou, Yingping; Yang, Xiaojing; Wei, Wensheng; Sun, Yujie; Tang, Chao


    Tracking the dynamics of genomic loci is important for understanding the mechanisms of fundamental intracellular processes. However, fluorescent labeling and imaging of such loci in live cells have been challenging. One of the major reasons is the low signal-to-background ratio (SBR) of images mainly caused by the background fluorescence from diffuse full-length fluorescent proteins (FPs) in the living nucleus, hampering the application of live cell genomic labeling methods. Here, combining bimolecular fluorescence complementation (BiFC) and transcription activator-like effector (TALE) technologies, we developed a novel method for labeling genomic loci (BiFC-TALE), which largely reduces the background fluorescence level. Using BiFC-TALE, we demonstrated a significantly improved SBR by imaging telomeres and centromeres in living cells in comparison with the methods using full-length FP.

  4. Bollasina Receives 2013 James R. Holton Junior Scientist Award: Response (United States)

    Bollasina, Massimo A.


    I am deeply honored to have been selected as this year's recipient of the James R. Holton Junior Scientist Award, and I receive it with heartfelt gratitude and humility. I clearly remember Peter Webster's call announcing the amazing news and how I literally remained speechless and overwhelmed. I would like to express my sincere appreciation to the Atmospheric Sciences section of AGU and the members of the award committee. I am even more appreciative to have been presented this award handed by two outstanding scientists—Peter Webster and Bill Lau—who have remarkably contributed to our understanding of the Asian monsoon and tropical climate, my area of expertise.

  5. James Van Allen The First Eight Billion Miles

    CERN Document Server

    Foerstner, Abigail


    Astrophysicist and space pioneer James Van Allen (1914-2006), for whom the Van Allen radiation belts were named, was among the principal scientific investigators for twenty-four space missions, including Explorer I in 1958, the first successful U.S. satellite; Mariner 2's 1962 flyby of Venus, the first successful mission to another planet; and the 1970's Pioneer 10 and Pioneer 11, missions that surveyed Jupiter and Saturn. Abigail Foerstner blends space science, drama, military agenda's, cold war politics, and the events of Van Allen's lengthy career to create the first biography of this highl

  6. James Baldwin: Biographical Dispatches on a Freedom Writer

    Directory of Open Access Journals (Sweden)

    Phillip Luke Sinitiere


    Full Text Available This essay presents the idea of James Baldwin as a freedom writer, the organizing idea of my biography in progress. As a freedom writer, Baldwin was a revolutionary intellectual, an essayist and novelist committed unfailingly to the realization of racial justice, interracial political equality, and economic democracy. While the book is still in process, this short essay narrates autobiographically how I came to meet and know Baldwin’s work, explains in critical fashion my work in relation to existing biographies, and reflects interpretively my thoughts-in- progress on this fascinating and captivating figure of immense historical and social consequence.

  7. Compensation and translation: James Ellroy’s White Jazz

    Directory of Open Access Journals (Sweden)

    Daria Protopopescu


    Full Text Available The current paper explores the Romanian translation of James Ellroy’s text “White Jazz”, with a view to explaining away the translator’s choices. The main issues at hand are the solutions provided for the ellipsis present throughout the novel and the slang used by the author, which is typical of L.A.’s ’60’s. The paper provides theoretical data supporting the translator’s choice of rendering certain slang expressions by paraphrase, explanation or even coinage of new words. We also look into how much has been compensated for and what was lost during the process of translation.

  8. Just how literal is the King James Version?


    Jan (JH) Kroeze; Manie (CM) van den Heever; Bertus (AJ) van Rooy


    Many scholars have the perception that the King James Version (KJV) is a literal translation. However, it is not so easy to define the concept of "literal translation". The simplest definition may be to regard it as word-for-word translation. However, when one compares the KJV carefully with the original Hebrew Bible, there are numerous instances where lexical items are changed to adapt the idiom to that of the target language. In this article, a measuring instrument will be proposed and u...

  9. Thomas James Walker (1835-1916): Surgeon and general practitioner. (United States)

    Thomas, Martyn


    Thomas James Walker was a surgeon and general practitioner who worked in the city of Peterborough at a time when there were changes and innovations in the practice of medicine. After training in medicine and surgery at Edinburgh University, he qualified in London in 1857. He was a pioneer of laryngoscopy. He played an important role in introducing antiseptic surgery to the Peterborough Infirmary and was instrumental in the development of the operating theatre which opened in 1894. He was a philanthropist and collector of Roman and Saxon artefacts. In 1915, he was recognized as an outstanding member of the Peterborough community when he was offered the Freedom of the City.


    Directory of Open Access Journals (Sweden)



    Full Text Available This paper argues that Measure for Measure is a difficult play to perform because it has problematic themes, especially the theme of sexuality, that clash with the way of life and thinking of contemporary society. As such, any director who chooses to stage it must consider these difficulties and how to present them in a natural manner without making the audience feel that the whole production is contrived. The directors of the two major productions discussed in this paper tried their best to present a Measure for Measure that would be acceptable to the modern society. It is evident that there are many interpretations of the Duke and Isabella's characters and also of Isabella's reaction to the Duke's proposal at the end of the play. It can be concluded that no interpretation is wrong because each actor or director brings with him his own reading of the play, and every reading has been influenced by other performances and textual criticisms. Since Measure for Measure is a thematically rich play, it should not be confined to a single interpretation. The different performances of Measure for Measure have proven that theatre is experimental as well as ageless. Because it is a brilliant play with a myriad of interpretations, Measure for Measure will not cease to be a favourite for directors in times to come. It is not wrong to predict that fans of Shakespeare in general and of Measure for Measure in particular can look forward to many more productions.For experienced Shakespeare observers all performances are thrice-told tales. The perceiving eye absorbs the performance even as the mind's eye attends to the text. Both are augmented by the inner ear buzzing with those other voices, both critical and dramatic, carried by the observer into the theatre.(Crowl, Samuel 1992: 3

  11. A random walk on water (Henry Darcy Medal Lecture) (United States)

    Koutsoyiannis, D.


    the history of philosophy of science (cf. Laplace's demon), is, at the same time, one of the founders of probability theory, which he regarded as "nothing but common sense reduced to calculation". This harmonizes with James Clerk Maxwell's view that "the true logic for this world is the calculus of Probabilities" and was more recently and epigrammatically formulated in the title of Edwin Thompson Jaynes's book "Probability Theory: The Logic of Science" (2003). Abandoning dichotomous logic, either on ontological or epistemic grounds, we can identify randomness or stochasticity with unpredictability. Admitting that (a) uncertainty is an intrinsic property of nature; (b) causality implies dependence of natural processes in time and thus suggests predictability; but, (c) even the tiniest uncertainty (e.g., in initial conditions) may result in unpredictability after a certain time horizon, we may shape a stochastic representation of natural processes that is consistent with Karl Popper's indeterministic world view. In this representation, probability quantifies uncertainty according to the Kolmogorov system, in which probability is a normalized measure, i.e., a function that maps sets (areas where the initial conditions or the parameter values lie) to real numbers (in the interval [0, 1]). In such a representation, predictability (suggested by deterministic laws) and unpredictability (randomness) coexist, are not separable or additive components, and it is a matter of specifying the time horizon of prediction to decide which of the two dominates. An elementary numerical example has been devised to illustrate the above ideas and demonstrate that they offer a pragmatic and useful guide for practice, rather than just pertaining to philosophical discussions. A chaotic model, with fully and a priori known deterministic dynamics and deterministic inputs (without any random agent), is assumed to represent the hydrological balance in an area partly covered by vegetation

  12. The hunters of humanity: creatures of horror in M. R. James's ghost stories


    Oryshchuk, Nataliya


    In his ghost stories, M.R. James disclosed the most irrational and fearful aspects of archaic demonology still haunting the modern world. He turns humans into prey species, hunted and haunted by repulsive insect- and spider-like demons. This paper offers a closer look at the creatures of horror and the recurrent theme of the hunt in James's ghost stories, viewing them in the context of Victorian evolutionary theories as well as traditional medieval beliefs. James's protagonists, unimaginative...

  13. Henry's Constants of Persistent Organic Pollutants by a Group-Contribution Method Based on Scaled-Particle Theory. (United States)

    Razdan, Neil K; Koshy, David M; Prausnitz, John M


    A group-contribution method based on scaled-particle theory was developed to predict Henry's constants for six families of persistent organic pollutants: polychlorinated benzenes, polychlorinated biphenyls, polychlorinated dibenzodioxins, polychlorinated dibenzofurans, polychlorinated naphthalenes, and polybrominated diphenyl ethers. The group-contribution model uses limited experimental data to obtain group-interaction parameters for an easy-to-use method to predict Henry's constants for systems where reliable experimental data are scarce. By using group-interaction parameters obtained from data reduction, scaled-particle theory gives the partial molar Gibbs energy of dissolution, Δg̅ 2 , allowing calculation of Henry's constant, H 2 , for more than 700 organic pollutants. The average deviation between predicted values of log H 2 and experiment is 4%. Application of an approximate van't Hoff equation gives the temperature dependence of Henry's constants for polychlorinated biphenyls, polychlorinated naphthalenes, and polybrominated diphenyl ethers in the environmentally relevant range 0-40 °C.

  14. [Crusading and Chronicle Writing on the Medieval Baltic Frontier: A Companion to the Chronicle of Henry of Livonia] / Michael Amundsen

    Index Scriptorium Estoniae

    Amundsen, Michael


    Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the Chronicle of Henry of Livonia / edited by Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham : Ashgate, 2011

  15. The Henry-Saltwater Intrusion Benchmark – Alternatives in Multiphysics Formulations and Solution Strategies

    Directory of Open Access Journals (Sweden)

    E Holzbecher


    Full Text Available In a classical paper Henry set up a conceptual model for simulating saltwater intrusion into coastal aquifers. Up to now the problem has been taken up by software developers and modellers as a benchmark for codes simulating coupled flow and transport in porous media. The Henry test case has been treated using different numerical methods based on various formulations of differential equations. We compare several of these approaches using multiphysics software. We model the problem using Finite Elements, utilizing the primitive variables and the streamfunction approach, both with and without using the Oberbeck-Boussinesq assumption. We compare directly coupled solvers with segregated solver strategies. Changing finite element orders and mesh refinement, we find that models based on the streamfunction converge 2-4 times faster than runs based on primitive variables. Concerning the solution strategy, we find an advantage of Picard iterations compared to monolithic Newton iterations.

  16. DNA-Catalyzed Henry Reaction in Pure Water and the Striking Influence of Organic Buffer Systems

    Directory of Open Access Journals (Sweden)

    Marleen Häring


    Full Text Available In this manuscript we report a critical evaluation of the ability of natural DNA to mediate the nitroaldol (Henry reaction at physiological temperature in pure water. Under these conditions, no background reaction took place (i.e., control experiment without DNA. Both heteroaromatic aldehydes (e.g., 2-pyridinecarboxaldehyde and aromatic aldehydes bearing strong or moderate electron-withdrawing groups reacted satisfactorily with nitromethane obeying first order kinetics and affording the corresponding β-nitroalcohols in good yields within 24 h. In contrast, aliphatic aldehydes and aromatic aldehydes having electron-donating groups either did not react or were poorly converted. Moreover, we discovered that a number of metal-free organic buffers efficiently promote the Henry reaction when they were used as reaction media without adding external catalysts. This constitutes an important observation because the influence of organic buffers in chemical processes has been traditionally underestimated.

  17. A French description of German psychology laboratories in 1893 by Victor Henri, a collaborator of Binet. (United States)

    Nicolas, Serge; Barnes, Marissa E; Murray, David J


    There is a rich tradition of writings about the foundation of psychology laboratories, particularly in the United States but also in France. Various documents exist concerning former German laboratories in American and French literature. But the most interesting French paper was certainly written by a young psychologist named Victor Henri (1872-1940) who was a close collaborator of Alfred Binet (1857-1911) in the 1890s. Visiting various psychology laboratories, he wrote, in 1893, a clear description of the laboratories of Wundt, G. E. Müller, Martius and Ebbinghaus. An English translation is given of Henri's paper and the historical importance of his contribution is here expounded by contrasting the German and French psychologies of the time.

  18. A tale of TALE, PREP1, PBX1, and MEIS1: Interconnections and competition in cancer. (United States)

    Blasi, Francesco; Bruckmann, Chiara; Penkov, Dmitry; Dardaei, Leila


    We report the latest structural information on PREP1 tumor suppressor, the specific "oncogene" and "tumor suppressive" signatures of MEIS1 and PREP1, the molecular rules regulating PREP1 and MEIS1 binding to DNA, and how these can change depending on the interaction with PBX1, cell-type, neoplastic transformation, and intracellular concentration. As both PREP1 and MEIS1 interact with PBX1 they functionally compete with each other. PREP1, PBX1, and MEIS1 TALE-class homeodomain transcription factors act in an interdependent and integrated way in experimental tumorigenesis. We also pool together the plethora of data available in human cancer databanks and connect them with the available molecular information. The emerging picture suggests that a similarly basic approach might be used to better dissect and define other oncogenes and suppressors and better understand human cancer. © 2017 The Authors. BioEssays Published by WILEY Periodicals, Inc.

  19. "Audacity or Precision": The Paradoxes of Henri Villat's Fluid Mechanics in Interwar France


    Aubin , David


    In Interwar France, Henri Villat became the true leader of theoretical researches on fluid mechanics. Most of his original work was done before the First World War; it was highly theoretical and its applicability was questioned. After having organized the first post-WWI International Congress of Mathematicians in 1920, Villat became the editor of the famous Journal de math\\'ematiques pure et appliqu\\'es and the director of the influential book series "M\\'emorial des sciences math\\'ematiques."...

  20. Henry Fayol’s 14 Principles of Management: Implications for Libraries and Information Centres


    Uzuegbu, C. P.; Nnadozie, C. O.


    This paper focuses generally on the ‘fourteen principles of management’ by Henri Fayol. However, it specifically analyses their application to and implications for libraries and information centres. An extensive review of published works on management generally, and library management in particular, was conducted. This yielded vital insights on the original meaning and later modifications of these principles, as well as their application in the management of various organisation...

  1. Staging Henry Fielding: The Author-Narrator in Tom Jones On Screen


    Løfaldli, Eli


    As recent adaptation theory has shown, classic-novel adaptation typically sets issues connected to authorship and literal and figurative ownership into play. This key feature of such adaptations is also central to the screen versions of Henry Fielding’s Tom Jones (1749). In much of Fielding’s fiction, the narrator, typically understood as an embodiment of Fielding himself, is a particularly prominent presence. The author-narrator in Tom Jones is no exception: not only is his presence strongly...

  2. VIDEO: Dr. Henry Rodriguez - Proteogenomics in Cancer Medicine | Office of Cancer Clinical Proteomics Research (United States)

    Dr. Henry Rodriguez, director of the Office of Cancer Clinical Proteomics Research (OCCPR) at NCI, speaks with ecancer television at WIN 2017 about the translation of the proteins expressed in a patient's tumor into a map for druggable targets. By combining genomic and proteomic information (proteogenomics), leading scientists are gaining new insights into ways to detect and treat cancer due to a more complete and unified understanding of complex biological processes.

  3. Henry Agard Wallace, the Iowa Corn Yield Tests, and the Adoption of Hybrid Corn


    Richard C. Sutch


    This research report makes the following claims: 1] There was not an unambiguous economic advantage of hybrid corn over the open-pollinated varieties in 1936. 2] The early adoption of hybrid corn before 1937 can be better explained by a sustained propaganda campaign conducted by the U.S. Department of Agriculture at the direction of the Secretary of Agriculture, Henry Agard Wallace. The Department's campaign echoed that of the commercial seed companies. The most prominent hybrid seed company,...

  4. Review: Henry E. Brady & David Collier (Hrsg.) (2004). Rethinking Social Inquiry: Diverse Tools, Shared Standards


    Catón, Matthias


    Das Buch Rethinking Social Inquiry, herausgegeben von Henry E. BRADY und David COLLIER, ist eine Antwort auf den Band von KING, KEOHANE und VERBA (1994), in dem versucht wird, Standards der quantitativen Forschung in der qualitativen Forschung einzuführen. Die Autoren des hier rezensierten Buchs kritisieren viele der Vorschläge, da sie argumentieren, dass qualitative Forschung anderer Werkzeuge bedürfe. Trotzdem stimmen sie zu, dass die Grundlagen des Forschungsaufbaus ähnlich sind. Das Buch ...

  5. Review: Henry E. Brady & David Collier (Eds.) (2004). Rethinking Social Inquiry: Diverse Tools, Shared Standards


    Matthias Catón


    Das Buch Rethinking Social Inquiry, herausgegeben von Henry E. BRADY und David COLLIER, ist eine Antwort auf den Band von KING, KEOHANE und VERBA (1994), in dem versucht wird, Standards der quantitativen Forschung in der qualitativen Forschung einzuführen. Die Autoren des hier rezensierten Buchs kritisieren viele der Vorschläge, da sie argumentieren, dass qualitative Forschung anderer Werkzeuge bedürfe. Trotzdem stimmen sie zu, dass die Grundlagen des Forschungsaufbaus ähnlich sind. Das Buch ...

  6. Pelecitus helicinus Railliet & Henry, 1910 (Filarioidea, Dirofilariinae and Other Nematode Parasites of Brazilian Birds

    Directory of Open Access Journals (Sweden)

    Oniki Yoshika


    Full Text Available We report Pelecitus helicinus Railliet & Henry, 1910 from 13 species of birds of 2 orders and 7 families, collected from the states of São Paulo and Mato Grosso, Brazil. All 13 constitute new host records for this nematode. In addition, we report the first record of Aprocta golvani Diaz-Ungria, 1963 from Brazil and Monasa nigrifrons (Bucconidae, as well as a number of other nematode records from Neotropical birds.

  7. Henri Fayol, théoricien de l’entreprise innovante


    Hatchuel , Armand; Segrestin , Blanche


    International audience; Have we correctly read Henri Fayol? His work is still reduced to general principles of administration that seem rigid and trivial. Yet, he has been a great innovative leader that considered scientific research as a major task of the business executive. A new reading of Fayol's masterpiece shows that he introduced sophisticated notions: " the unknown " , " the program of action " , " the advancement " , which meaning was erased by his translators or forgotten. Coming fr...

  8. Henri Fayol. Performativity of his ideas and oblivion of their creator


    Dumez , Hervé


    Henri Fayol formulated one of the first theories of management and allows us to see how one of the first scientific approaches of management could or could not perform management practices. Therefore, Fayol is particularly interesting from the point of view of performativity (Callon, 1998, 2007, MacKenzie et al., 2007, Muniesa, 2014). The case is all the richer because it presents the rare characteristic of a direct confrontation between two rival theories, his and Taylor's, at the level of t...

  9. James Weldon Johnson and the Speech Lab Recordings

    Directory of Open Access Journals (Sweden)

    Chris Mustazza


    Full Text Available On December 24, 1935, James Weldon Johnson read thirteen of his poems at Columbia University, in a recording session engineered by Columbia Professor of Speech George W. Hibbitt and Barnard colleague Professor W. Cabell Greet, pioneers in the field that became sociolinguistics. Interested in American dialects, Greet and Hibbitt used early sound recording technologies to preserve dialect samples. In the same lab where they recorded T.S. Eliot, Gertrude Stein, and others, James Weldon Johnson read a selection of poems that included several from his seminal collection God’s Trombones and some dialect poems. Mustazza has digitized these and made them publicly available in the PennSound archive. In this essay, Mustazza contextualizes the collection, considering the recordings as sonic inscriptions alongside their textual manifestations. He argues that the collection must be heard within the frames of its production conditions—especially its recording in a speech lab—and that the sound recordings are essential elements in an hermeneutic analysis of the poems. He reasons that the poems’ original topics are reframed and refocused when historicized and contextualized within the frame of The Speech Lab Recordings.

  10. Film-Induced Tourism in the Way of Saint James

    Directory of Open Access Journals (Sweden)

    Lucrezia Lopez


    Full Text Available This research paper proposes an analytical approach to the study of the phenomenon of the film-induced pilgrimage tourism, along one of the most historical and relevant European cultural route: the Way of St. James or Camino de Santiago.In the present study, and in order to point out the relation between film broadcast and film-induced tourism, we combine the review of the Jacobean cinema with the statistical analysis of the pilgrims arrived to Santiago de Compostela during the last decade. So, our main aim is to analyse the repercussion of the Jacobean Cinema in the attractiveness of the Way of St. James as tourism destination. We take into consideration the role of the film producers and we also ponder on the marketing policies of the Autonomous Community, which are aimed at promoting the pilgrim’s routes, the Cathedral and the city of Santiago de Compostela. The cinema has played a less important role until now, in comparison with the impact of travel guides and the Jacobean literature, but it is increasing its impact in the international tourism markets. Recently, the American film The Way can be considered to be the first promoter of the film-induced tourism, because the arrivals of pilgrims from USA have been increased after the broadcast of this film since 2010.

  11. Should bulk cloudwater or fogwater samples obey Henry's law

    Energy Technology Data Exchange (ETDEWEB)

    Pandis, S.N.; Seinfeld, J.H. (Department of Chemical Engineering and Environmental Quality Laboratory, California Institute of Technology, Pasadena, CA (USA))


    In this work we prove that mixing of droplets with different {ital p}H that are individually in Henry's law equilibrium with the surrounding atmosphere always results in a bulk mixture that is supersaturated with weak acids like S(IV) and HCOOH and bases like NH{sub 3} with respect to the original atmosphere. The degree of supersaturation of the bulk liquid water sample for a particular species depends on its dissociation constant, on the initial {ital p}H of the bulk droplet mixture, and on the distribution of the {ital p}H and of the liquid water over the droplet spectrum. High supersaturations result only when the {ital p}H of the bulk droplet mixture exceeds the {ital p}K{sub {ital a}} of the species, in which {ital p}H range large {ital p}H differences among droplets of different sizes lead to large deviations from Henry's law for the bulk mixture. The deviation is shown to depend on the ratio of the arithmetic mean to the harmonic mean of the hydrogen ion concentrations of the droplets with the liquid water content used was weighting factor in the calculation of the means. The theory developed can explain observed discrepancies from Henry's law in atmospheric samples and also other observed phenomena like the reported increase of {ital p}H values of bulk aqueous samples during storage. {copyright} American Geophysical Union 1991

  12. The last ride of Henry II of France: orbital injury and a king's demise. (United States)

    Eftekhari, Kian; Choe, Christina H; Vagefi, M Reza; Eckstein, Lauren A


    Jousting was a popular pastime for royalty in the Renaissance era. Injuries were common, and the eye was particularly at risk from the splinters of the wooden lance. On June 30, 1559, Henry II of France participated in a jousting tournament to celebrate two royal weddings. In the third match, Gabriel de Montgomery struck Henry on the right shoulder and the lance splintered, sending wooden shards into his face and right orbit. Despite being cared for by the prominent physicians Ambroise Paré and Andreas Vesalius, the king died 10 days later and was found to have a cerebral abscess. The wound was not explored immediately after the injury; nevertheless, wooden foreign bodies were discovered in the orbit at the time of autopsy. The dura had not been violated, suggesting that an infection may have traveled from the orbit into the brain. Nostradamus and Luca Guarico, the astrologer to the Medici family, had prophesied the death of Henry II of France, but he ignored their warnings and thus changed the course of history in Renaissance Europe. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Oxalate Content of the Herb Good-King-Henry, Blitum Bonus-Henricus

    Directory of Open Access Journals (Sweden)

    Wanying Li


    Full Text Available The total, soluble and insoluble oxalate contents of the leaves, stems and buds of Good-King-Henry (Blitum Bonus-Henricus were extracted and measured using HPLC chromatography. The large, mature leaves contained 42% more total oxalate than in the small leaves and the soluble oxalate content of the large leaves was 33% higher than the smaller leaves. Cooking the mixed leaves, stems and buds in boiling water for two minutes significantly (p < 0.05 reduced the total oxalate when compared to the raw plant parts. Pesto sauce made from mixed leaves contained 257 mg total oxalate/100 g fresh weight; this was largely made up of insoluble oxalates (85% of the total oxalate content. Soup made from mixed leaves contained lower levels of total oxalates (44.26 ± 0.49 mg total oxalate/100 g fresh weight and insoluble oxalate made up 49% of the oxalate contents. The levels of oxalates in the Good-King-Henry leaves were high, suggesting that the leaves should be consumed occasionally as a delicacy because of their unique taste rather than as a significant part of the diet. However, the products made from Good-King-Henry leaves indicated that larger amounts could be consumed as the oxalate levels were reduced by dilution and processing.

  14. Generation of dTALEs and Libraries of Synthetic TALE-Activated Promoters for Engineering of Gene Regulatory Networks in Plants. (United States)

    Schreiber, Tom; Tissier, Alain


    Transcription factors with programmable DNA-binding specificity constitute valuable tools for the design of orthogonal gene regulatory networks for synthetic biology. Transcription activator-like effectors (TALEs), as natural transcription regulators, were used to design, build, and test libraries of synthetic TALE-activated promoters (STAPs) that show a broad range of expression levels in plants. In this chapter, we present protocols for the construction of artificial TALEs and corresponding STAPs.

  15. Fairy-tale planet: creative science writing for children (United States)

    Lanza, Tiziana; D'Addezio, Giuliana


    During public events organized by our Institute sometimes we have predisposed a corner to entertain primary school children with fairy-tales about the planet. In that occasion we realized that even if children could take part in other activities more in fashion such as laboratories, theatre performances, exhibits, they were very attracted by fairy tales, such an "ancient" tradition. This year within the projects "alternanza scuola-lavoro" we are planning to involve also the students of the secondary schools to learn themselves how to animate a fairy-tale corner for children. The "alternanza scuola lavoro" (interchange school/work) has been recently introduced in the Italian school as a methodology for implementing the second cycle teaching. The general purpose is to ensure that 15 to 18 years old students, beside the access to basic knowledge, can acquire skills in the employment and real work environments experiencing other teaching methods based both on knowledge and know-how. We will then start a new adventure by investigating what will be the best way to introduce children to creative science writing for the planet. The aim would be that of creating a format suitable for children either for writing all together a planet fairy-tale in class, or individually. The final goal is to raise awareness about the environmental problems by stimulating in scholars their own creativity.

  16. Computational Drafting of Plot Structures for Russian Folk Tales. (United States)

    Gervás, Pablo

    The plots of stories are known to follow general patterns in terms of their overall structure. This was the basic tenet of structuralist approaches to narratology. Vladimir Propp proposed a procedure for the generation of new tales based on his semi-formal description of the structure of Russian folk tales. This is one of the first existing instances of a creative process described procedurally. The present paper revisits Propp's morphology to build a system that generates instances of Russian folk tales. Propp's view of the folk tale as a rigid sequence of character functions is employed as a plot driver, and some issues that Propp declared relevant but did not explore in detail-such as long-range dependencies between functions or the importance of endings-are given computational shape in the context of a broader architecture that captures all the aspects discussed by Propp. A set of simple evaluation metrics for the resulting outputs is defined inspired on Propp's formalism. The potential of the resulting system for providing a creative story generation system is discussed, and possible lines of future work are discussed.

  17. Tell-Tale Signs: Reflection towards the Acquisition of Academic ...

    African Journals Online (AJOL)

    Tell-Tale Signs: Reflection towards the Acquisition of Academic Discourses as Second Languages. ... Stellenbosch Papers in Linguistics ... After enrolling in a sign language course, we – lecturers teaching academic discourses – decided to explore this phenomenon and determine the implications for pedagogical practice.

  18. The Lobster Tale: An Exercise in Critical Thinking (United States)

    Stepanovich, Paul L.


    Professors in management and business are encouraged to incorporate critical thinking as an objective in their courses. "The Lobster Tale" provides an opportunity to engage students in various levels of critical thinking, ranging from a relatively superficial reading to an examination of the deeper, often hidden issues. Using the foundations of…

  19. Fairy Tale and Trauma in Toni Morrison's Home

    NARCIS (Netherlands)

    Visser, Irene


    The literary work of Toni Morrison is famous for its rich intertexuality, interweaving narrative, contemporary history, and tales and motifs from oral storytelling traditions. Her tenth novel, Home (2013), is no exception. It contains disturbing and dark narratives of childhood abuse, war trauma,

  20. Generation of TALE-Based Designer Epigenome Modifiers. (United States)

    Nitsch, Sandra; Mussolino, Claudio


    Manipulation of gene expression can be facilitated by editing the genome or the epigenome. Precise genome editing is traditionally achieved by using designer nucleases which are generally exploited to eliminate a specific gene product. Upon the introduction of a site-specific DNA double-strand break (DSB) by the nuclease, endogenous DSB repair mechanisms are in turn harnessed to induce DNA sequence changes that can result in target gene inactivation. Minimal off-target effects can be obtained by endowing designer nucleases with the highly specific DNA-binding domain (DBD) derived from transcription activator-like effectors (TALEs). In contrast, epigenome editing allows gene expression control without inducing changes in the DNA sequence by specifically altering epigenetic marks, as histone tails modifications or DNA methylation patterns within promoter or enhancer regions. Importantly, this approach allows both up- and downregulation of the target gene expression, and the effect is generally reversible. TALE-based designer epigenome modifiers combine the high specificity of TALE-derived DBDs with the power of epigenetic modifier domains to induce fast and long-lasting changes in the epigenetic landscape of a target gene and control its expression. Here we provide a detailed description for the generation of TALE-based designer epigenome modifiers and of a suitable reporter cell line to easily monitor their activity.

  1. From DNA binding to transcriptional activation: Is the TALE complete? (United States)

    Bobola, Nicoletta


    How transcription factors (TFs) control enhancer and promoter functions to effect changes in gene expression is an important question. In this issue, Hau et al. (2017. J. Cell Biol. show that the TALE TF MEIS recruits the histone modifier PARP1/ARTD1 at promoters to decompact chromatin and activate transcription. © 2017 Bobola.

  2. A Salamander Tale: Effective Exhibits and Attitude Change (United States)

    Rollins, Jeffrey; Watson, Sunnie Lee


    Little information exists regarding intention behind the design and development of Extension outreach and educational exhibits. An evaluation of response to the exhibit "A Salamander Tale" indicates that the methods used to develop the exhibit resulted in an effective way to present information to an adult audience. Survey questions were…

  3. Libraries of Synthetic TALE-Activated Promoters: Methods and Applications. (United States)

    Schreiber, T; Tissier, A


    The discovery of proteins with programmable DNA-binding specificities triggered a whole array of applications in synthetic biology, including genome editing, regulation of transcription, and epigenetic modifications. Among those, transcription activator-like effectors (TALEs) due to their natural function as transcription regulators, are especially well-suited for the development of orthogonal systems for the control of gene expression. We describe here the construction and testing of libraries of synthetic TALE-activated promoters which are under the control of a single TALE with a given DNA-binding specificity. These libraries consist of a fixed DNA-binding element for the TALE, a TATA box, and variable sequences of 19 bases upstream and 43 bases downstream of the DNA-binding element. These libraries were cloned using a Golden Gate cloning strategy making them usable as standard parts in a modular cloning system. The broad range of promoter activities detected and the versatility of these promoter libraries make them valuable tools for applications in the fine-tuning of expression in metabolic engineering projects or in the design and implementation of regulatory circuits. © 2016 Elsevier Inc. All rights reserved.

  4. The TALE face of Hox proteins in animal evolution. (United States)

    Merabet, Samir; Galliot, Brigitte


    Hox genes are major regulators of embryonic development. One of their most conserved functions is to coordinate the formation of specific body structures along the anterior-posterior (AP) axis in Bilateria. This architectural role was at the basis of several morphological innovations across bilaterian evolution. In this review, we traced the origin of the Hox patterning system by considering the partnership with PBC and Meis proteins. PBC and Meis belong to the TALE-class of homeodomain-containing transcription factors and act as generic cofactors of Hox proteins for AP axis patterning in Bilateria. Recent data indicate that Hox proteins acquired the ability to interact with their TALE partners in the last common ancestor of Bilateria and Cnidaria. These interactions relied initially on a short peptide motif called hexapeptide (HX), which is present in Hox and non-Hox protein families. Remarkably, Hox proteins can also recruit the TALE cofactors by using specific PBC Interaction Motifs (SPIMs). We describe how a functional Hox/TALE patterning system emerged in eumetazoans through the acquisition of SPIMs. We anticipate that interaction flexibility could be found in other patterning systems, being at the heart of the astonishing morphological diversity observed in the animal kingdom.

  5. Control of plant architecture by distinctive TALE homeobox gene interactions

    NARCIS (Netherlands)

    Bao, D.|info:eu-repo/dai/nl/304838063


    In eukaryotes, transcription factor (TF)-based network is a widely used mechanism to regulate fundamental developmental processes. Both animals and plants utilize three-amino-acid-loop-extension (TALE) homeodomain (HD) transcription factors to subdivide their body plan. In animals, MEIS/PBC TF

  6. Modern Baltic fairy tales in drama / Anneli Saro

    Index Scriptorium Estoniae

    Saro, Anneli, 1968-


    Jaan Tätte näidendist "Ristumine peateega, ehk, Muinasjutt kuldsest kalakesest" ("The highway crossing, or, The tale of a golden fish", tuntud ka pealkirjaga "Bungee jumping" ) ja Inga Ābele näidendist "Tumedad hirved" (The dark deer")

  7. Telling Different Tales: Possible Childhoods in Children's Literature (United States)

    Sreenivas, Deepa


    This article draws on the insights/questions that emerged while putting together a set of stories for children published in a series named "Different Tales." These stories, set in Dalit and other minority communities, problematize the normative grids through which we view "childhood" as they depict the complex ways in which…

  8. Effectiveness of an implementation optimisation intervention aimed at increasing parent engagement in HENRY, a childhood obesity prevention programme - the Optimising Family Engagement in HENRY (OFTEN) trial: study protocol for a randomised controlled trial. (United States)

    Bryant, Maria; Burton, Wendy; Cundill, Bonnie; Farrin, Amanda J; Nixon, Jane; Stevens, June; Roberts, Kim; Foy, Robbie; Rutter, Harry; Hartley, Suzanne; Tubeuf, Sandy; Collinson, Michelle; Brown, Julia


    Family-based interventions to prevent childhood obesity depend upon parents' taking action to improve diet and other lifestyle behaviours in their families. Programmes that attract and retain high numbers of parents provide an enhanced opportunity to improve public health and are also likely to be more cost-effective than those that do not. We have developed a theory-informed optimisation intervention to promote parent engagement within an existing childhood obesity prevention group programme, HENRY (Health Exercise Nutrition for the Really Young). Here, we describe a proposal to evaluate the effectiveness of this optimisation intervention in regard to the engagement of parents and cost-effectiveness. The Optimising Family Engagement in HENRY (OFTEN) trial is a cluster randomised controlled trial being conducted across 24 local authorities (approximately 144 children's centres) which currently deliver HENRY programmes. The primary outcome will be parental enrolment and attendance at the HENRY programme, assessed using routinely collected process data. Cost-effectiveness will be presented in terms of primary outcomes using acceptability curves and through eliciting the willingness to pay for the optimisation from HENRY commissioners. Secondary outcomes include the longitudinal impact of the optimisation, parent-reported infant intake of fruits and vegetables (as a proxy to compliance) and other parent-reported family habits and lifestyle. This innovative trial will provide evidence on the implementation of a theory-informed optimisation intervention to promote parent engagement in HENRY, a community-based childhood obesity prevention programme. The findings will be generalisable to other interventions delivered to parents in other community-based environments. This research meets the expressed needs of commissioners, children's centres and parents to optimise the potential impact that HENRY has on obesity prevention. A subsequent cluster randomised controlled pilot

  9. The King James Bible and the Politics of Religious Education: Secular State and Sacred Scripture (United States)

    Gearon, Liam


    This article provides an outline historical-educational analysis of the King James Bible from its 1611 publication through to its four-hundredth anniversary commemoration in 2011. With particular focus on England, the article traces the educational impact of the King James Bible and charts, in the country of its origin, its progressive decline in…

  10. Op zoek naar James Bond: media-pelgrimages, fans en masculiniteit

    NARCIS (Netherlands)

    Reijnders, S.


    Visiting the settings of popular films and tv series has become a growing niche in the tourist market. Little is known about what makes these visits so appealing. This question is explored on the basis of the case of James Bond. Twenty-three interviews were conducted with James Bond fans who had

  11. 78 FR 50458 - Entergy Nuclear Operations, Inc., James A. Fitzpatrick Nuclear Power Plant, Vermont Yankee... (United States)


    ... Nuclear Operations, Inc., James A. Fitzpatrick Nuclear Power Plant, Vermont Yankee Nuclear Power Station... that the NRC take action with regard to James A. Fitzpatrick Nuclear Power Plant, Vermont Yankee.... Fitzpatrick Nuclear Power Plant (Fitzpatrick), Vermont Yankee Nuclear Power Station (Vermont Yankee), and...

  12. 75 FR 11575 - James A. Fitzpatrick Nuclear Power Plant Environmental Assessment and Finding of No Significant... (United States)


    ... Power Plant Environmental Assessment and Finding of No Significant Impact The U.S. Nuclear Regulatory...), for the operation of the James A. FitzPatrick Nuclear Power Plant (JAFNPP) located in Oswego County... the Final Environmental Statement for the James A. FitzPatrick Nuclear Power Plant, Docket No. 50-333...

  13. James Joyce kui religiooni subjekt ja objekt / Kalle Käsper

    Index Scriptorium Estoniae

    Käsper, Kalle, 1952-


    Arvustus: Joyce, James. Dublinlased : [novellid] / inglise keelest tõlkinud Jaak Rähesoo. 2. tr. [Tallinn] : Varrak, 2003 ; Joyce, James. Kunstniku noorpõlveportree : [romaan] / inglise keelest tõlkinud [ja järelsõna:] Jaak Rähesoo. [Tallinn] : Varrak, 2003; vt ka vastukaja: Raudam, Toomas. Kontra Käsper // Sirp (2003) 20. juuni, lk. 5

  14. 75 FR 49994 - James Stephen Ferguson, D.M.D.; Revocation of Registration (United States)


    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 09-64] James Stephen Ferguson, D.M.D.; Revocation of Registration On July 24, 2009, the Deputy Assistant Administrator, Office of Diversion Control, Drug Enforcement Administration (DEA), issued an Order to Show Cause to James Stephen...

  15. Bloomsday: James Joyce's Ulysses Celebrated as Theatrical Event

    Directory of Open Access Journals (Sweden)

    Willmar Sauter


    Full Text Available James Joyce had decided that 16 June 1904 should be the one day in the life of Leopold Bloom, about which he wrote his 800 page novel Ulysses. In his book, Joyce actually followed Mr Bloom that entire day, from his getting up and having the nowadays famous kidney breakfast, to the late evening, when he had to break into his own house on 7 Eccle Street to have a drink with Stephen Dedalus, the other main figure of the novel. The centenary of that very day took, accordingly, place in 2004. I have borrowed the identity of Mr Bloom to describe some street scenes from the centennial celebrations of Bloomsday in Dublin. After this intro-ductory presentation, part two of this article will attempt to analyse Bloomsday in terms of a Theatrical Event, embedded in an unusual and striking playing culture. In a third part, Mr Bloom will once more be allowed to make some concluding comments.

  16. Launch Window Trade Analysis for the James Webb Space Telescope (United States)

    Yu, Wayne H.; Richon, Karen


    The James Webb Space Telescope (JWST) is a large-scale space telescope mission designed to study fundamental astrophysical questions ranging from the formation of the universe to the origin of planetary systems and the origins of life. JWSTs orbit design is a Libration Point Orbit (LPO) around the Sun-Earth/Moon (SEM) L2 point for a planned mission lifetime of 10.5 years. The launch readiness period for JWST is from Oct 1st, 2018 November 30th, 2018. This paper presents the first launch window analysis for the JWST observatory using finite-burn modeling; previous analysis assumed a single impulsive midcourse correction to achieve the mission orbit. The physical limitations of the JWST hardware stemming primarily from propulsion, communication and thermal requirements alongside updated mission design requirements result in significant launch window within the launch readiness period. Future plans are also discussed.

  17. Solar System Observations with the James Webb Space Telescope (United States)

    Norwood, James; Hammel, Heidi; Milam, Stefanie; Stansberry, John; Lunine, Jonathan; Chanover, Nancy; Hines, Dean; Sonneborn, George; Tiscareno, Matthew; Brown, Michael; hide


    The James Webb Space Telescope (JWST) will enable a wealth of new scientific investigations in the near- and mid-infrared, with sensitivity and spatial/spectral resolution greatly surpassing its predecessors. In this paper, we focus upon Solar System science facilitated by JWST, discussing the most current information available concerning JWST instrument properties and observing techniques relevant to planetary science. We also present numerous example observing scenarios for a wide variety of Solar System targets to illustrate the potential of JWST science to the Solar System community. This paper updates and supersedes the Solar System white paper published by the JWST Project in 2010. It is based both on that paper and on a workshop held at the annual meeting of the Division for Planetary Sciences in Reno, NV, in 2012.

  18. The scientific papers of James Clerk Maxwell, vol.I

    CERN Document Server

    Maxwell, James Clerk


    One of the greatest theoretical physicists of the 19th century, James Clerk Maxwell is best known for his studies of the electromagnetic field. The 101 scientific papers of this two-volume set, arranged chronologically, testify to Maxwell's profound scientific legacy and include the preliminary explorations that culminated in his most famous work, A Treatise on Electricity and Magnetism. One of the nineteenth century's most significant papers, "A Dynamical Theory of the Electromagnetic Field," appears here, along with similarly influential expositions of Maxwell's dynamical theory of gases. The author's extensive range of interests is well represented, from his discussions of color blindness and the composition of Saturn's rings to his essays on geometrical optics, ether, and protecting buildings from lightning. His less technical writings are featured as well, including items written for the Encyclopedia Britannica and Nature magazine, book reviews, and popular lectures. Striking in their originality, these ...

  19. Astronaut James S. Voss Performs Tasks in the Destiny Laboratory (United States)


    Astronaut James S. Voss, Expedition Two flight engineer, works with a series of cables on the EXPRESS Rack in the United State's Destiny laboratory on the International Space Station (ISS). The EXPRESS Rack is a standardized payload rack system that transports, stores, and supports experiments aboard the ISS. EXPRESS stands for EXpedite the PRocessing of Experiments to the Space Station, reflecting the fact that this system was developed specifically to maximize the Station's research capabilities. The EXPRESS Rack system supports science payloads in several disciplines, including biology, chemistry, physics, ecology, and medicine. With the EXPRESS Rack, getting experiments to space has never been easier or more affordable. With its standardized hardware interfaces and streamlined approach, the EXPRESS Rack enables quick, simple integration of multiple payloads aboard the ISS. The system is comprised of elements that remain on the ISS, as well as elements that travel back and forth between the ISS and Earth via the Space Shuttle.

  20. Swyer-James-Macleod's syndrome. A case report

    International Nuclear Information System (INIS)

    Pacheco C, Dario; Ojeda Leon, Paulina; Varo Acosta, Humberto; Salcedo Veles, Patricia; Salazar Juan Carlos


    This is a case report about a 67 years-old female patient with respiratory syndrome of 8 years with cough and dyspnoea. End-inspiration crackles in the pulmonary auscultation were found in left hemi thorax. Chest x-ray in expiration and inspiration showed hyperluscency and air trapping in the same hemi-thorax. Chest high-resolution CT revealed a low sized, oligohemic left lung with cylindrical bronchiectasis. Perfusion scintigraphy 99Tc labeled showed markedly left lung hypo-perfusion. Mild obstructive process was found in pulmonary function test. Lung biopsy of lingula reported bronchiolitis obliterans. Considered all the results that were obtained from clinical, x-ray and histopathology, a diagnosis of Swyer-James-Macleods syndrome was made

  1. Assimilating American Indians in James Fenimore Cooper’s Novels?

    Directory of Open Access Journals (Sweden)

    Peprník Michal


    Full Text Available The article employs critical concepts from sociology and anthropology to examine the stereotype of the Vanishing Indian and disclose its contradictory character. The article argues that in James Fenimore Cooper’s late novels from the 1840s a type of American Indian appears who can be regarded as a Vanishing Indian in many respects as he displays some slight degree of assimilation but at the same time he can be found to reveal a surprising amount of resistance to the process of vanishing and marginalization. His peculiar mode of survival and his mode of living demonstrate a certain degree of acculturation, which comes close to Gerald Vizenor’s survivance and for which I propose a term critical integration. I base my study on Susquesus (alias Trackless, Cooper’s less well-known character from The Littlepage Manuscripts, a three-book family saga.

  2. The case of James A. Garfield: a historical perspective. (United States)

    Weiner, Bradley K


    In 1881, President James A. Garfield was shot in the back and died 79 days later. During this time, many controversies arose that had repercussions for years to come. Who was to manage the President's care? A prominent local physician took on the case, but after Garfield's death, he was highly criticized for inappropriate care and for excluding more highly qualified surgeons. Where was the bullet? Multiple opinions were given including that of Alexander Graham Bell. The correct suggestion turned out to be that of a young, unknown assistant demonstrator of anatomy. What was the proper treatment? Local wound care, removal of the bullet, and laparotomy all were considered. Many have felt that the choice of treatment may have proved to be worse than the injury itself. What did the autopsy show? Even this was controversial, with different observers claiming different results. This historical perspective reviews the case as well the controversies that surrounded it.

  3. Henri Fayol’un Yönetim Düşüncesi Üzerine Notlar(Notes on Managerial Thought of Henry Fayol

    Directory of Open Access Journals (Sweden)

    Ramazan ŞENGÜL


    Full Text Available Henri Fayol, developed a managerial approach which is a perfect guide for both private and public sectors through focusing systematically upon managerial process. A major advantage of Fayol in creating a general managerial doctrine was his pratician side. His managerial thought which was developed in the early 20th century lasted up to our times. The distinguished characteristic of Fayol’s thought was studying the administrative reality through separating it into its functions, in that it helps to understand evolution and operation of organisations. The importance of his doctrine for today is that adapting contemporary managerial techniques into organisations of various kinds needs to refer Fayol’s managerial aproach in one way or another.


    Directory of Open Access Journals (Sweden)

    Ewa Piotrowska-Oberda


    Full Text Available The aim of this article is the quest for knowledge in "The King James Bible" (1611 in terms of quantitative and qualitative research methodology with the application of the statistical analysis tool Antconc. The quest for knowledge with the use of corpus research aims at discussing the Biblical concept of knowledge through the origin, the object of knowledge, its implications and its constant development. Knowledge is often seen as of divine nature, reflected in the soul of man. It is based not only on logical, but also on the spiritual and ethical reasoning. The object of knowledge is light, reflecting the divine nature of knowledge which exceeds the intellect to reach a deeper spiritual human reasoning. In "The King James Bible" (1611 the authors of New Testament consider human knowledge to be imperfect and partial. They emphasize the need for a spiritual man aiming at reaching a complete knowledge. This spiritual development is based on the relationship between knowledge and faith, as well as knowledge and love. For the authors of the books of the New Testament there is no dichotomy between both knowledge and faith and knowledge and love, because faith and love depend on knowledge that originates in the word of God and leads to spiritual development. From this perspective, religious knowledge, love and mercy as well as faith developed through the knowledge of the biblical text leads to the knowledge of God, the enlightening source of ultimate knowledge. Thus, in the spiritual development of man not only the knowledge and faith but also emotional intelligence, which expresses itself through love and charity as the safer guide in all controversial issues, are important.

  5. [Dr James Lovelock and story about GAIA hypothesis]. (United States)

    Gajić, Vladimir


    Gaia is the Anglo-Saxon term for the Hellenic term Gea or Ge, which means Earth. The GAIA hypothesis was launched almost 40 years ago by the famous chemist James Lovelock, who was engaged by the National Aeronautics and Space Administration (NASA) to create a sensitive instrument for searching forms of extraterrestrial life on other planets. Then he published the book The ages of GAIA, which perturbed the world's scientific public of those days. Lovelock struck upon this idea in the late sixties of the past century, during the space race with Russians, when he was hired hy the National Aeronautics and Space Administration to conduct a series of experiments to find and explore life forms on the planet Mars. Experiments executed by the American module Viking failed to trace any life form, as Lovelock had predicted. He called it a dead equilibrium. Then he turned to Earth, whose perspective is totally different from its first neighbors. Venus and Mars, and is far from a dead equilibrium. DAISYWORLD: In this hypothesis. Lovelock represents Earth as one living, giant super organism, composed of all living creatures and its material environnent. In that super organisnm, the level of oxygen, weather conditions, ocean salinity and so on are under constant influence of physical, chemical and biological processes, which provide the existence for such life forms on Earth. Dr James Lovelock represents a pioneer of climatology, and his hypothesis gives a unique insight into the correlation of dynamic processes on our planet, no matter whether they are of physical or biological nature.

  6. Physiology as the antechamber to metaphysics: the young William James's hope for a philosophical psychology. (United States)

    Croce, P J


    In the 5 years before 1878, when his career in psychology was becoming established, William James wrote a series of notes and reviews assessing the work of many of the pioneers in the new field. Adopting a public and confident voice, even while he was privately still uncertain and searching, James criticized the dogmatism of positivist and idealist claims to the study of the human brain and mind. In his short writings of 1873-1877, James started to formulate his own middle path. His first steps on that path show that he did not reject either scientific or philosophic inquiry; instead, he viewed scientific knowledge as a way to understand philosophical questions more deeply. Saving his sharpest critiques for positivism, James endorsed scientific investigation without materialist assmptions. While his career in psychology was still only a hope, James treated science as a means toward humanist insight.

  7. Staging Henry Fielding: The Author-Narrator in Tom Jones On Screen

    Directory of Open Access Journals (Sweden)

    Eli Løfaldli


    Full Text Available As recent adaptation theory has shown, classic-novel adaptation typically sets issues connected to authorship and literal and figurative ownership into play. This key feature of such adaptations is also central to the screen versions of Henry Fielding’s Tom Jones (1749. In much of Fielding’s fiction, the narrator, typically understood as an embodiment of Fielding himself, is a particularly prominent presence. The author-narrator in Tom Jones is no exception: not only is his presence strongly felt throughout the novel, but through a variety of means, ‘The History of Tom Jones, A Foundling’ is also distinctly marked as being under his control and ownership. The two adaptations of Fielding’s novel, a 1963 film and a 1997 television series, both retain the figure of the author-narrator, but differ greatly in their handling of this device and its consequent thematic ramifications. Although the 1963 film de-emphasises Henry Fielding’s status as proprietor of the story, the author-narrator as represented in the film’s voiceover commentary is a figure of authority and authorial control. In contrast, the 1997 adaptation emphasises Fielding’s ownership of the narrative and even includes the author-narrator as a character in the series, but this ownership is undermined by the irreverent treatment to which he is consistently subjected. The representations of Henry Fielding in the form of the author-narrator in both adaptations are not only indicative of shifting conceptions of authorship, but also of the important interplay between authorship, ownership and adaptation more generally.

  8. Development of low-energy X-ray spectrometry at the Laboratoire National Henri Becquerel

    International Nuclear Information System (INIS)

    Lepy, M.C.; Plagnard, J.


    In the frame of the French Metrology Institute, the Laboratoire National Henri Becquerel performs accurate characterization of semiconductor detectors that are in use in a number of applications. Their efficiency calibration, energy resolution and the detailed shape of their response function are parameters of interest for accurate processing of low-energy X-ray spectra to be applied to elements identification and fundamental research studies. The tools specifically developed for low-energy detectors calibration and characterization are described, from the use of radioactivity standard to the development of a tunable monochromatic X-ray source. (Author)

  9. Literary Practice according to Michel Henry: A Philosophical Introduction to his Novels

    Directory of Open Access Journals (Sweden)

    Jean-Baptiste Dussert


    Full Text Available Although the author of four novels, Michel Henry never produced an aesthetics of literature. The purpose of this article is, after a presentation of his philosophy of immanence and his concept of life, to locate where the literary practice takes place in his system. In this study, we are not interested in the poetic quality of his works, but in the possibility to base his singular creativity on his philosophical reflection. This leads us to insert literature in the vast phenomenon of culture and ethics, and to grasp the function of poetics in the struggle against barbarism.

  10. Ernest Henry Starling (1866-1927): the scientist and the man

    DEFF Research Database (Denmark)

    Henriksen, Jens H


    The pre-eminent achievements of the English physician and physiologist Ernest Henry Starling were his quantitative explanation of the transcapillary transport of fluid, the discovery of the first hormone, secretin, and his formulation of the law of the heart. In some ways Starling was an outsider...... and he was the centre of several scientific and social controversies. However, throughout his life he stressed fundamental scientific attitudes and ideas with remarkable persistence and power, although also balance, and his scientific achievements have stood the test of time....

  11. Elementos de política de gestión en Henry Mintzberg


    García-Álvarez, S. (Santiago); García-Martínez, A.N. (Alejandro Néstor); Múgica, F. (Fernando)


    El trabajo de investigación consistió en estudiar un buen número de los escritos de Henry Mintzberg y prácticamente todas sus obras relacionadas con los elementos de política de gestión: no únicamente los libros, sino numerosos artículos y textos relacionados. He leído también muchos libros y artículos de otros autores de management, como Drucker, Collins, Kotter, Pfeffer, Peters y varios más, para enriquecer el texto y contrastar posturas. He estudiado con particular interés y detenimiento l...

  12. Henri Walon: por uma teoria dialética na educação

    Directory of Open Access Journals (Sweden)

    Maria Inês Naujorks


    Full Text Available O texto aborda as principais idéias desenvolvidas por Henri Wallon. Tendo como método o materialismo dialético, seu projeto foi o de formular uma "ciência do homem". Para o autor o desenvolvimento é a síntese dialética do biológico e do social e só pode ser entendido à luz das contradições de um processo que se estende por toda vida toda.

  13. 75 FR 59237 - TRICARE Co-Pay Waiver at Captain James A. Lovell Federal Health Care Center Demonstration Project (United States)


    ... DEPARTMENT OF DEFENSE Office of the Secretary TRICARE Co-Pay Waiver at Captain James A. Lovell.... ACTION: Notice of TRICARE Co-Pay waiver at Captain James A. Lovell Federal Health Care Center... ``TRICARE Co-Pay Waiver at Captain James A. Lovell Federal Health Care (FHCC) Demonstration Project.'' Under...

  14. Environmental liabilities in Billings reservoir and its impacts on hydropower generation Plant Henry Borden; Os passivos ambientais no reservatorio Billings e os seus impactos na geracao hidroenergetica da Usina Henry Borden

    Energy Technology Data Exchange (ETDEWEB)

    Almeida, Daniel Ladeira [Universidade Federal do ABC (UFABC), Santo Andre, SP (Brazil)


    The primary assertion is that this article argues that the recovery in production of hydropower in Henry Borden (UHB) is the reduction of environmental liabilities in the Billings reservoir. In this context, the aim of this paper is to provide a first consideration of the possibility of recovery of production Henry Borden hydropower plant of recovering the multiple uses of the reservoir. From this perspective, we interviewed representatives of CETESB (Sanitation Environmental Technology Company) and EMAE (Metropolitan Water and Energy Company SA) for consideration of actions that include environmental policies aimed at increasing the production of electricity in Henry Borden in order to obtain results that may contribute to the multiple uses of the Billings reservoir. Noting that the range of laws aimed at protecting the water sources was limited to disjointed public policy that has reduced the resilience of the Billings reservoir. (author)

  15. Thirteen and two fairy tales on the energy turning point

    International Nuclear Information System (INIS)

    Keil, Guenter


    Inspired by the choices and changes in the German energy policy, the author proposes controversial texts under the form of tales on the German policy and situation regarding energy. These tales ironically address the German energy model, the uselessness of the seven stopped nuclear power plants, the low cost of the energy turnaround made by the German government, the environmental benefit of renewable energies, the high potential of energy savings, the new means of electricity storage, the electric car as means to store electricity, the low cost of solar energy ('Sun does not send any bill'), the wind energy (the wind turbine fleet in such place can supply so much households), the geothermal energy, the so-called technological leap, the benefit of decentralized energy production, the numerous jobs created by renewable energies, the ecologic electric current, and the search for a final nuclear waste disposal site

  16. Rapid and highly efficient construction of TALE-based transcriptional regulators and nucleases for genome modification

    KAUST Repository

    Li, Lixin


    Transcription activator-like effectors (TALEs) can be used as DNA-targeting modules by engineering their repeat domains to dictate user-selected sequence specificity. TALEs have been shown to function as site-specific transcriptional activators in a variety of cell types and organisms. TALE nucleases (TALENs), generated by fusing the FokI cleavage domain to TALE, have been used to create genomic double-strand breaks. The identity of the TALE repeat variable di-residues, their number, and their order dictate the DNA sequence specificity. Because TALE repeats are nearly identical, their assembly by cloning or even by synthesis is challenging and time consuming. Here, we report the development and use of a rapid and straightforward approach for the construction of designer TALE (dTALE) activators and nucleases with user-selected DNA target specificity. Using our plasmid set of 100 repeat modules, researchers can assemble repeat domains for any 14-nucleotide target sequence in one sequential restriction-ligation cloning step and in only 24 h. We generated several custom dTALEs and dTALENs with new target sequence specificities and validated their function by transient expression in tobacco leaves and in vitro DNA cleavage assays, respectively. Moreover, we developed a web tool, called idTALE, to facilitate the design of dTALENs and the identification of their genomic targets and potential off-targets in the genomes of several model species. Our dTALE repeat assembly approach along with the web tool idTALE will expedite genome-engineering applications in a variety of cell types and organisms including plants. © 2012 Springer Science+Business Media B.V.


    Directory of Open Access Journals (Sweden)

    Nikolay Govorov


    Full Text Available The article deals with the problem of children nurturing. Given the provisions of the recommended use of Russian national fairy tales in children nurturing. We consider the role of a fairy tale, as an aspect of the success of educational processes in a child immersed in the atmosphere of a modern cyber information of his being. It rips the need to address the problem of writing the words of imagery of Russian fairy tales.

  18. Rapid and highly efficient construction of TALE-based transcriptional regulators and nucleases for genome modification. (United States)

    Li, Lixin; Piatek, Marek J; Atef, Ahmed; Piatek, Agnieszka; Wibowo, Anjar; Fang, Xiaoyun; Sabir, J S M; Zhu, Jian-Kang; Mahfouz, Magdy M


    Transcription activator-like effectors (TALEs) can be used as DNA-targeting modules by engineering their repeat domains to dictate user-selected sequence specificity. TALEs have been shown to function as site-specific transcriptional activators in a variety of cell types and organisms. TALE nucleases (TALENs), generated by fusing the FokI cleavage domain to TALE, have been used to create genomic double-strand breaks. The identity of the TALE repeat variable di-residues, their number, and their order dictate the DNA sequence specificity. Because TALE repeats are nearly identical, their assembly by cloning or even by synthesis is challenging and time consuming. Here, we report the development and use of a rapid and straightforward approach for the construction of designer TALE (dTALE) activators and nucleases with user-selected DNA target specificity. Using our plasmid set of 100 repeat modules, researchers can assemble repeat domains for any 14-nucleotide target sequence in one sequential restriction-ligation cloning step and in only 24 h. We generated several custom dTALEs and dTALENs with new target sequence specificities and validated their function by transient expression in tobacco leaves and in vitro DNA cleavage assays, respectively. Moreover, we developed a web tool, called idTALE, to facilitate the design of dTALENs and the identification of their genomic targets and potential off-targets in the genomes of several model species. Our dTALE repeat assembly approach along with the web tool idTALE will expedite genome-engineering applications in a variety of cell types and organisms including plants.

  19. A Function of Dream Narratives in Fairy Tale


    Judit Gulyás


    In Hungarian variants of some fairy tale types (especially ATU 315,707, 725) the operation of a peculiar dream narrative can be observed: the characters use an embedded dream narrative to communicate information. The agent of knowledge conveys information to a mediating person and in doing so (s)he also governs that when the mediator conveys information to the actual addressee (recipient), the mediator must explain the origin of the conveyed knowledge to the recipient by referring to a fictio...

  20. Kierkegaard se, drei grossen ideen” en die ini- siasie van henry van eeden (sewe dae b y die silbersteins

    Directory of Open Access Journals (Sweden)

    L. S. Venter


    Full Text Available Die doel van Henry se verblyf by die Silbersteins word vroeg in Sewe dae verwoord as Jock tydens die eerste aandbyeenkoms sê dat Henry „van sekere gevestigde idees” (p. 16 ontslae moet raak. Ook mrs. Silberstein beskou dit as noodsaaklik dat sy on­ skuld vemietig moet word (p. 22. Op die oggendwandeling van die tweede dag herhaal Jock sy stelling van die vorige aand en voeg daaraan toe dat daar baie dinge is wat Henry ,,sal moet leer en verleer” (p. 28. Vir die modeme mens, wat „van die vrug van kennis geëet” het, is daar „geen illussies meer nie” (p. 32.

  1. Musical Tale as a Reading Comprehension Resource in the Classroom

    Directory of Open Access Journals (Sweden)

    Lucía Martínez Vázquez


    Full Text Available Reading comprehension is a complex process, whose teaching involves multiple factors, as highlighted by Psychology, Didactics of languages, and others disciplines. Nevertheless, theoretical frameworks need to be applied by means of innovative practices and resources. The aim of this work is to present an innovation implemented in 2016-2017 in the third year of primary school, in the frame of an action-research, with the objective of reinforcing the learning of reading. In order to cope whit the comprehension difficulties involved in attention and concentration abilities, a didactic intervention was designed with the musical tale as a resource. Different approaches to this sort of text, integrated in diverse activities, facilitated the learning of active listening of tales, expressing reading, and guided the attention of readers to metacognitive strategies. The experience allows better identify some difficulties in the reading process, and prove the usefulness of the musical tale, as a meaningful resource to support the teaching and learning of reading.

  2. A Transcription Activator-Like Effector (TALE) Toolbox for Genome Engineering (United States)

    Sanjana, Neville E.; Cong, Le; Zhou, Yang; Cunniff, Margaret M.; Feng, Guoping; Zhang, Feng


    Transcription activator-like effectors (TALEs) are a class of naturally occurring DNA binding proteins found in the plant pathogen Xanthomonas sp. The DNA binding domain of each TALE consists of tandem 34-amino acid repeat modules that can be rearranged according to a simple cipher to target new DNA sequences. Customized TALEs can be used for a wide variety of genome engineering applications, including transcriptional modulation and genome editing. Here we describe a toolbox for rapid construction of custom TALE transcription factors (TALE-TFs) and nucleases (TALENs) using a hierarchical ligation procedure. This toolbox facilitates affordable and rapid construction of custom TALE-TFs and TALENs within one week and can be easily scaled up to construct TALEs for multiple targets in parallel. We also provide details for testing the activity in mammalian cells of custom TALE-TFs and TALENs using, respectively, qRT-PCR and Surveyor nuclease. The TALE toolbox described here will enable a broad range of biological applications. PMID:22222791

  3. Engineering DNA Backbone Interactions Results in TALE Scaffolds with Enhanced 5-Methylcytosine Selectivity. (United States)

    Rathi, Preeti; Witte, Anna; Summerer, Daniel


    Transcription activator-like effectors (TALEs) are DNA major-groove binding proteins widely used for genome targeting. TALEs contain an N-terminal region (NTR) and a central repeat domain (CRD). Repeats of the CRD selectively recognize each one DNA nucleobase, offering programmability. Moreover, repeats with selectivity for 5-methylcytosine (5mC) and its oxidized derivatives can be designed for analytical applications. However, both TALE domains also nonspecifically interact with DNA phosphates via basic amino acids. To enhance the 5mC selectivity of TALEs, we aimed to decrease the nonselective binding energy of TALEs. We substituted basic amino acids with alanine in the NTR and identified TALE mutants with increased selectivity. We then analysed conserved, DNA phosphate-binding KQ diresidues in CRD repeats and identified further improved mutants. Combination of mutations in the NTR and CRD was highly synergetic and resulted in TALE scaffolds with up to 4.3-fold increased selectivity in genomic 5mC analysis via affinity enrichment. Moreover, transcriptional activation in HEK293T cells by a TALE-VP64 construct based on this scaffold design exhibited a 3.5-fold increased 5mC selectivity. This provides perspectives for improved 5mC analysis and for the 5mC-conditional control of TALE-based editing constructs in vivo.

  4. TALE activators regulate gene expression in a position- and strand-dependent manner in mammalian cells. (United States)

    Uhde-Stone, Claudia; Cheung, Edna; Lu, Biao


    Transcription activator-like effectors (TALEs) are a class of transcription factors that are readily programmable to regulate gene expression. Despite their growing popularity, little is known about binding site parameters that influence TALE-mediated gene activation in mammalian cells. We demonstrate that TALE activators modulate gene expression in mammalian cells in a position- and strand-dependent manner. To study the effects of binding site location, we engineered TALEs customized to recognize specific DNA sequences located in either the promoter or the transcribed region of reporter genes. We found that TALE activators robustly activated reporter genes when their binding sites were located within the promoter region. In contrast, TALE activators inhibited the expression of reporter genes when their binding sites were located on the sense strand of the transcribed region. Notably, this repression was independent of the effector domain utilized, suggesting a simple blockage mechanism. We conclude that TALE activators in mammalian cells regulate genes in a position- and strand-dependent manner that is substantially different from gene activation by native TALEs in plants. These findings have implications for optimizing the design of custom TALEs for genetic manipulation in mammalian cells. Copyright © 2013 Elsevier Inc. All rights reserved.

  5. Theoretical Insight of Physical Adsorption for a Single Component Adsorbent + Adsorbate System: II. The Henry Region

    KAUST Repository

    Chakraborty, Anutosh


    The Henry coefficients of a single component adsorbent + adsorbate system are calculated from experimentally measured adsorption isotherm data, from which the heat of adsorption at zero coverage is evaluated. The first part of the papers relates to the development of thermodynamic property surfaces for a single-component adsorbent + adsorbate system1 (Chakraborty, A.; Saha, B. B.; Ng, K. C.; Koyama, S.; Srinivasan, K. Langmuir 2009, 25, 2204). A thermodynamic framework is presented to capture the relationship between the specific surface area (Ai) and the energy factor, and the surface structural and the surface energy heterogeneity distribution factors are analyzed. Using the outlined approach, the maximum possible amount of adsorbate uptake has been evaluated and compared with experimental data. It is found that the adsorbents with higher specific surface areas tend to possess lower heat of adsorption (ΔH°) at the Henry regime. In this paper, we have established the definitive relation between Ai and ΔH° for (i) carbonaceous materials, metal organic frameworks (MOFs), carbon nanotubes, zeolites + hydrogen, and (ii) activated carbons + methane systems. The proposed theoretical framework of At and AH0 provides valuable guides for researchers in developing advanced porous adsorbents for methane and hydrogen uptake. © 2009 American Chemical Society.

  6. James Clerk Maxwell perspectives on his life and work

    CERN Document Server

    McCartney, Mark; Whitaker, Andrew


    James Clerk Maxwell (1831-1879) had a relatively brief, but remarkable life, lived in his beloved rural home of Glenlair, and variously in Edinburgh, Aberdeen, London and Cambridge. His scholarship also ranged wide - covering all the major aspects of Victorian natural philosophy. He was one of the most important mathematical physicists of all time, coming only after Newton and Einstein. In scientific terms his immortality is enshrined in electromagnetism and Maxwell's equations, but as this book shows, there was much more to Maxwell than electromagnetism, both in terms of his science and his wider life. Maxwell's life and contributions to science are so rich that they demand the expertise of a range of academics - physicists, mathematicians, and historians of science and literature - to do him justice. The various chapters will enable Maxwell to be seen from a range of perspectives. Chapters 1 to 4 deal with wider aspects of his life in time and place, at Aberdeen, King's College London and the Cavendish Labo...

  7. A New Observing Tool for the James Clerk Maxwell Telescope (United States)

    Folger, Martin; Bridger, Alan; Dent, Bill; Kelly, Dennis; Adamson, Andy; Economou, Frossie; Hirst, Paul; Jenness, Tim

    A new Observing Tool (OT) has been developed at the UK Astronomy Technology Centre, Edinburgh, UK and the Joint Astronomy Centre, Hilo, Hawaii, USA. It is based on the Gemini Observing Tool and provides the first graphical observation preparation tool for the James Clerk Maxwell Telescope (JCMT) as well as being the first use of the OT for a non-optical/IR telescope. The OT allows the observer to assemble high level Science Programs using graphical representations of observation components such as instrument, target, and filter. This is later translated into low level control sequences for telescope and instruments. The new OT is designed to work on multiple telescopes: currently the UK Infrared Telescope (UKIRT) and JCMT. Object-oriented design makes the inclusion of telescope and instrument specific packages easy. The OT is written in Java using GUI packages such as Swing and JSky. A new component for the JCMT OT is the graphical Frequency Editor for Heterodyne instruments. It can be used to specify parameters such as frequencies, bandwidths, and sidebands of multiple subsystems, while graphically displaying the front-end frequency, emission lines and atmospheric transmission. In addition, Flexible Scheduling support has been added to the OT. The observer can define scheduling constraints by arranging observations graphically. Science Programs can be saved as XML or sent directly from the OT to a database (via SOAP).

  8. Impacts of James Bay project on Cree communities

    International Nuclear Information System (INIS)

    Senecal, P.; Egre, D.


    The LaGrande hydroelectric project in northwest Quebec, originally begun in 1972, was blocked by the Cree Indians and a negotiated settlement was reached in 1975 to continue it in exchange for compensation, land rights, and other matters. The James Bay and Northern Quebec Agreement contained provisions regulating the use of land and aimed at preserving the traditional Cree way of life. Other complementary agreements were signed in the 1980s. The impact of river-system modifications on wildlife harvesting and the effect of access roads on Cree communities are discussed. Flooding of hunting lands affected some traplines, and the low productivity of shore habitats and the high levels of mercury in some fish have greatly limited use of the LaGrande reservoirs for other purposes. Stream navigation at some communities was made more difficult because of changed river flows. The impact of the roads has been more positive, since the roads have facilitated trade and reduced local prices of many goods, and made wildlife harvesting easier and more evenly distributed. An income security program for hunters, fishers, and trappers has helped preserve a traditional lifestyle. A sharp increase in salary income, indicating consolidation of the employment market in the region, is the most significant economic impact of the LaGrande project agreement. 6 refs

  9. Growing Physics and Astronomy at James Madison University (United States)

    Whisnant, C. Steven


    James Madison University is a public, primarily undergraduate institution with a student enrollment of over 18,000. We have a 10.8% minority population and a 60:40 female/male ratio. Drawing 29% of its students from other states, JMU serves a diverse student body. Since the mid '90's, the Department of Physics and Astronomy has grown to 110 majors. There are 15 tenured/tenure-track and 6 non-tenure-track full-time faculty in the department. Graduation rates have grown from five or fewer/year to typically 15-20/year. Eleven faculty are currently engaged in externally funded research with undergraduates. In the 2007-2008 academic year, 45 students were engaged in research. We produced a total of 89 publications and presentations that included 27 students as authors or co-authors. The growth of our department over the last decade is due to a variety of reforms. Foremost among the changes under the control of the department are the initiation of our multi-track BS and BA degree programs and a renewed focus on undergraduate research. These and other significant factors contributing to our success such as student recruiting, outreach, teaching and research integration/balance, promotion of a department culture, visibility on-and off-campus, and university support will be discussed. )

  10. An Interdisciplinary Program in Materials Science at James Madison University. (United States)

    Hughes, Chris


    Over the past decade a core group of faculty at James Madison University has created an interdisciplinary program in materials science that provides our students with unique courses and research experiences that augment the existing, high-quality majors in physics and astronomy, chemistry and biochemistry, geology and environmental science, mathematics and statistics, and integrated science and technology. The university started this program by creating a Center for Materials Science whose budget is directly allocated by the provost. This source of funds acts as seed money for research, support for students, and a motivating factor for each of the academic units to support the participation of their faculty in the program. Courses were created at the introductory and intermediate level that are cross-listed by the departments to encourage students to enroll in them as electives toward their majors. Furthermore, the students are encouraged to participate in undergraduate research in materials since this is the most fundamental unifying theme across the disciplines. This talk will cover some of the curricular innovations that went into the design of the program to make it successful, examples of faculty and student research and how that feeds back into the classroom, and success stories of the interactions that have developed between departments because of this program. Student outcomes and future plans to improve the program will also be discussed.

  11. A Scientific Revolution: The Hubble and James Webb Space Telescopes (United States)

    Gardner, Jonathan P.


    Astronomy is going through a scientific revolution, responding to a flood of data from the Hubble Space Telescope, other space missions, and large telescopes on the ground. In this talk, I will discuss some of the important discoveries of the last decade, from dwarf planets in the outer Solar System to the mysterious dark energy that overcomes gravity to accelerate the expansion of the Universe. The next decade will be equally bright with the newly refurbished Hubble and the promise of its successor, the James Webb Space Telescope. An infrared-optimized 6.5m space telescope, Webb is designed to find the first galaxies that formed in the early universe and to peer into the dusty gas clouds where stars and planets are born. With MEMS technology, a deployed primary mirror and a tennis-court sized sunshield, the mission presents many technical challenges. I will describe Webb's scientific goals, its design and recent progress in constructing the observatory. Webb is scheduled for launch in 2014.

  12. James Lee Byars 1/2 an autobiography, sourcebook

    CERN Document Server

    Byars, James Lee; Eleey, Peter


    "I see my autobiography as an arbitrary segment of so many pages of time, of things that I have paid attention to at this point in my life," wrote James Lee Byars (1932-1997) in 1969. He was then 37, about half the average male lifespan at the time, and accordingly thought it appropriate to write his "1/2 autobiography." Byars' art ranged from highly refined objects to extremely minimal performance and events, and books, ephemera and correspondence that he distributed widely among friends and colleagues. Today, more than 15 years after his death, assessments of his art must negotiate Byars' performance of his charismatic self in his life and art. For his first major posthumous survey in the US, exhibition curators Magalí Arriola and Peter Eleey decided to produce a catalogue in two "halves," playing on his "1/2 autobiography": a catalogue of the exhibition itself, including new scholarship, and a sourcebook of primary documents. 1/2 an Autobiography, Sourcebook constitutes the latter volume--a reference guid...

  13. Optical transmission for the James Webb Space Telescope (United States)

    Lightsey, Paul A.; Gallagher, Benjamin B.; Nickles, Neal; Copp, Tracy


    The fabrication and coating of the mirrors for the James Webb Space Telescope has been completed. The spectral reflectivity of the protected gold coated beryllium mirrors has been measured. The predicted end-of-life transmission through the telescope builds from these values. The additional phenomena that have been analyzed are contamination effects and effects of the environment for the JWST operation about the Earth-Sun L2 Lagrange libration point. The L2 environment analysis has been based on radiation testing of mirror samples and hypervelocity testing to assess the micrometeoroid impact effects. The mirror showed no change in reflectance over the VIS-SWIR wavelengths after exposure to 6-9 Grad (Si) that simulated 6 years orbiting the L2 Lagrange point. The effects of hypervelocity particle impacts on the mirrors from test data has been extrapolated to the to the anticipated flux characteristics for micrometeoroids at the L2 environment. The results show that the micrometeoroid effects are orders of magnitude below the particulate contamination effects. The final end-of-life transmission for the mirrors including all of these phenomena will meet the performance requirements for JWST.


    Directory of Open Access Journals (Sweden)

    Ceisy Nita Wuntu


    Full Text Available This study aims at connecting the vanishing flora, fauna and its Relation to the Indian removal policy in Coopers The Leatherstocking Tales. This research applies an American Studies interdisciplinary principle supplemented by the myth and symbol theory proposed by Henry Nash Smith. Smith claimed the importance of imaginative works in revealing American culture. He declared that the historical, anthropological and cultural, sociological, and ecological data as covered in this research can be equipped by data from imaginative works. Hence, in this research, those data are presented integratedly in their context of past and present. In this research, in order to highlight environmental matters in Coopers The Leatherstocking Tales, the analysis covers the data above that are integrated with the data revealed in The Leatherstocking Tales as a whole by employing the concept of ecocriticism. The spirit of the immigrants to have a better life in the new world, stimulated by its rich, lush and beautiful circumstances, in fact, is not an aim of a sustainable life. The desire to improve their life is not enough without using and treating its environment wisely as well as facing it with the environmental conservation paradigm. The spirit of doing the exploitation is a consequence of western humanism value. The reason of coming to America to avoid the population density as well as the competition of life cannot be attained when the immigrants experience the same population density and harsh competition as in their old world and when the beautiful nature disappears, the forests become cities, the tranquility becomes noisy and crowded, and the people experience the uncomfortable life that many kinds of conflict can follow. It is not on the right path when they cannot maintain the grandeur of nature, because they are not directing their way to the right, sustainable way of life as alerted and meant by Cooper. Ecologically, the superabundance of the land when

  15. Mapping Henry: Synchrotron-sourced X-ray fluorescence mapping and ultra-high-definition scanning of an early Tudor portrait of Henry VIII

    Energy Technology Data Exchange (ETDEWEB)

    Dredge, Paula; Ives, Simon [Art Gallery of New South Wales (AGNSW), Sydney, NSW (Australia); Howard, Daryl L.; Spiers, Kathryn M. [Australian Synchrotron, Clayton, VIC (Australia); Yip, Andrew [Art Gallery of New South Wales (AGNSW), Sydney, NSW (Australia); University of New South Wales, Laboratory for Innovation in Galleries, Libraries, Archives and Museums (iGLAM), National Institute for Experimental Arts, Sydney, NSW (Australia); Kenderdine, Sarah [University of New South Wales, Laboratory for Innovation in Galleries, Libraries, Archives and Museums (iGLAM), National Institute for Experimental Arts, Sydney, NSW (Australia)


    A portrait of Henry VIII on oak panel c. 1535 has recently undergone technical examination to inform questions regarding authorship and the painting's relationship to a group of similar works in the collections of the National Portrait Gallery, London, and the Society of Antiquaries. Due to previous conservation treatments of the painting, the conventional transmission X-radiograph image was difficult to interpret. As a result, the painting underwent high-definition X-ray fluorescence (XRF) elemental mapping on the X-ray fluorescence microscopy beamline of the Australian Synchrotron. Scans were conducted at 12.6 and 18.5 keV, below and above the lead (Pb) L edges, respectively. Typical scan parameters were 120 μm pixel size at 7 ms dwell time, with the largest scan covering an area 545 x 287 mm{sup 2} collected in 23 h (10.8 MP). XRF mapping of the panel has guided the conservation treatment of the painting and the revelation of previously obscured features. It has also provided insight into the process of making of the painting. The informative and detailed elemental maps, alongside ultra-high-definition scans of the painting undertaken before and after varnish and over-paint removal, have assisted in comparison of the finely painted details with the London paintings. The resolution offered by the combination of imaging techniques identifies pigment distribution at an extremely fine scale, enabling a new understanding of the artist's paint application. (orig.)

  16. Mapping Henry: Synchrotron-sourced X-ray fluorescence mapping and ultra-high-definition scanning of an early Tudor portrait of Henry VIII

    International Nuclear Information System (INIS)

    Dredge, Paula; Ives, Simon; Howard, Daryl L.; Spiers, Kathryn M.; Yip, Andrew; Kenderdine, Sarah


    A portrait of Henry VIII on oak panel c. 1535 has recently undergone technical examination to inform questions regarding authorship and the painting's relationship to a group of similar works in the collections of the National Portrait Gallery, London, and the Society of Antiquaries. Due to previous conservation treatments of the painting, the conventional transmission X-radiograph image was difficult to interpret. As a result, the painting underwent high-definition X-ray fluorescence (XRF) elemental mapping on the X-ray fluorescence microscopy beamline of the Australian Synchrotron. Scans were conducted at 12.6 and 18.5 keV, below and above the lead (Pb) L edges, respectively. Typical scan parameters were 120 μm pixel size at 7 ms dwell time, with the largest scan covering an area 545 x 287 mm 2 collected in 23 h (10.8 MP). XRF mapping of the panel has guided the conservation treatment of the painting and the revelation of previously obscured features. It has also provided insight into the process of making of the painting. The informative and detailed elemental maps, alongside ultra-high-definition scans of the painting undertaken before and after varnish and over-paint removal, have assisted in comparison of the finely painted details with the London paintings. The resolution offered by the combination of imaging techniques identifies pigment distribution at an extremely fine scale, enabling a new understanding of the artist's paint application. (orig.)

  17. Characteristics of Sediments in the James River Estuary, Virginia, 1968 (NODC Accession 7001081) (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This report presents data on the physical and chemical characteristics of bottom sediments in the James River estuary, Virgina. The data were generated as part of a...

  18. "Attacking the Citadel": James Moncreiff's Proposals to Reform Scottish Education, 1851-69. (United States)

    Bain, Wilson H.


    A review of the parliamentary actions of Lord Advocate James Moncreiff to create a fully national Scottish educational system against the opposition by church groups reluctant to lose control over parish schools and schoolmasters. (SJL)

  19. Integrated Modeling for the James Webb Space Telescope (JWST) Project: Structural Analysis Activities (United States)

    Johnston, John; Mosier, Mark; Howard, Joe; Hyde, Tupper; Parrish, Keith; Ha, Kong; Liu, Frank; McGinnis, Mark


    This paper presents viewgraphs about structural analysis activities and integrated modeling for the James Webb Space Telescope (JWST). The topics include: 1) JWST Overview; 2) Observatory Structural Models; 3) Integrated Performance Analysis; and 4) Future Work and Challenges.

  20. James Wertsi ja SaxEsti ühiskontsert. "Valge gospel" asub taas tuurile

    Index Scriptorium Estoniae


    Ameerika laulja ja kitarristi James Wertsi ning saksofonikvarteti SaxEst kontserdituurist Eestis algusega 1. dets. Haljala rahvamajast. Kontserdituurist "Valge gospel" alates 11. dets. kuues Eestimaa kirikus (viimane kontsert 20. dets. Tallinna Linnahallis)

  1. Sir James Paget: Paget's disease of the nipple, Paget's disease of bone. (United States)

    Ellis, Harold


    Sir James Paget was one of the 'great' Victorians. Eminent as a surgeon, pathologist and teacher, his nobility of character and application to his work made him a leader in his profession in that age of great men.

  2. James Hurman "Sisuturundus ei anna kiiret lühiajalist efekti" / intervjueerinud Hando Sinisalu, Heidi Tiik

    Index Scriptorium Estoniae

    Hurman, James


    Intervjuu Passwordi konverentsil ettekandega "Loovus ja äriedu: tõestus selle kohta, et loovad reklaamid suurendavad ärilist edukust" esineva James Hurmaniga edukatest kampaaniatest ja sisuturunduse efektiivsusest

  3. Aerial photographic water color variations from pollution in the James River (United States)

    Bressette, W. E.


    A photographic flight was made over the James River on May 17, 1977. The data show that, in general, James River water has very high sunlight reflectance. In the Bailey Bay area this reflectance is drastically reduced. Also shown is a technique for normalizing off-axis variations in radiance film exposure from camera falloff and uneven sunlight conditions to the nadir value. After data normalization, a spectral analysis is performed that identifies Bailey Creek water in James River water. The spectral results when compared with laboratory spectrometer data indicate that reflectance from James River water is dominated by suspended matter, while the substance most likely responsible for reduced reflectance in Bailey Creek water is dissolved organic carbon.

  4. Data collection and evaluation of continuity detail for John James Audubon Bridge No. 61390613004101. (United States)


    This report summarizes findings from monitoring data that was collected over a two-year period from Bridge No. : 61390613004101 in the John James Audubon Project, which was formerly designated as Bridge #2 prior to : construction completion. The brid...

  5. Presidential Green Chemistry Challenge: 2010 Academic Award - James C. Liao and Easel Biotechnologies, LLC (United States)

    Presidential Green Chemistry Challenge 2010 award winner, Dr. James C. Liao, genetically engineered microorganisms to make higher alcohols (with 3 to 8 carbon atoms) from glucose or directly from carbon dioxide (CO2).

  6. Konstruksi Realitas Pengguna Ponsel Cerdas Berdasarkan Pesan Penempatan Merek dalam Film James Bond: Spectre


    Hafiz, M. Faisal


    This study entitled "Construction of Reality of Smartphone User Based on Branding Placement Message in James Bond: Spectre Film". The research is going to examine the relations between the process of branding placement of Sony Xperia Z5 to the movie-viewer who use smartphone from a variety of backgrounds. Researcher focus on how smartphone users adapt to their social needs, how subjective meaning of Sony Xperia Z5 upon the branding placement message in James Bond: Spectre, a...

  7. Kunst, kunstiajalugu ja visuaalkultuur / James Elkins ; intervjueerinud Maarin Mürk

    Index Scriptorium Estoniae

    Elkins, James, 1955-


    Kultuuriteaduste ja kunstide doktorikool korraldas 20.-22. sept. 2010 Eesti Kunstiakadeemia kunstikultuuri teaduskonnas ameerika kunstiteadlase James Elkensi seminari "Kunst, kunstiajalugu ja visuaalkultuuri uuringud. Uurimise ja kirjastamise probleeme ja kontseptsioone tänapäeval". James Elkensiga kunstiteadusest, sellest, kuidas visuaalkultuuri uurimine paneb küsimärgi alla senise kunstiajaloo ning kuidas on võimalik kirjutada ka Euroopa traditsioonist väljapoole jäävat kunstiajalugu, siinsest kunstiajaloo uurimisest ja kirjutamisest

  8. Neurosurgical Work during the Napoleonic Wars: George James Guthrie's Experience. (United States)

    Roux, Franck-Emmanuel


    Involved in what is still considered, along with the two world wars of the 20th century, as one of the major conflicts in Europe, George James Guthrie (1785-1856) was the most famous English army surgeon of the Napoleonic wars. After treating the injured throughout the Peninsular Campaign (1808-1814), in 1815 and then in 1842 he published two major books dealing with cranial and brain injuries, among other topics. In these books, we can find, for example, an early description of the plantar reflex further described by Joseph Babinsky, accurate descriptions of the clinical signs of intracranial hypertension, and details of the physiopathology of subdural and epidural haematomas. Skull fractures are also discussed intensively, along with the indications for trepanation, a much-debated issue at the turn of the 19th century. The dura was often the limit of the surgical field for Guthrie. Nevertheless, he tried to rationalize the use of trepanation and favoured its use in two main cases: in cases of depressed skull bones, jammed bone fragments or debris irritating the dura or the brain and in cases of life-threatening cerebral compression caused by supposed blood clots. In their works, Guthrie and his contemporaries did not address neurosurgery in the modern sense of the word, but rather 'cranial surgery' in most cases. Guthrie, who saw so many patients with brain injuries and amputations, failed to understand that cerebral functions could be localized to the cortex and neglected to describe the phantom limb phenomenon, as did most of his contemporaries. © 2016 S. Karger AG, Basel.

  9. Interview with James Bradner. Interviewed by Hannah Coaker. (United States)

    Bradner, James E


    James E Bradner is an Assistant Professor in Medicine at Harvard Medical School (MA, USA) as well as a Staff Physician in the Division of Hematologic Malignancies at Dana-Farber Cancer Institute (MA, USA). The present research focus of the Bradner laboratory concerns the discovery and optimization of prototype drugs targeting cancer gene regulation. The clinical objective of the Bradner group is to deliver novel therapeutics for human clinical investigation in hematologic diseases. Bradner's awards and honors include the Damon Runyon-Rachleff Innovation Award, the Smith Family Award for Excellence in Biomedical Research, the Dunkin' Donuts Rising Star Award and the HMS Distinguished Excellence in Teaching Award. He is a member of the American Society of Clinical Investigation, the American Society of Hematology, the American Chemical Society and the American Association of Cancer Research. His recent research has been published in Nature, Cell, Nature Chemical Biology and the Journal of the American Chemical Society. He has authored more than 20 US Patent applications, licensed to five pharmaceutical companies, and is a scientific founder of Acetylon Pharmaceuticals, SHAPE Pharmaceuticals, Tensha Therapeutics and Syros Pharmaceuticals. Bradner received his AB from Harvard University, his MD from the University of Chicago (IL, USA) and a MMS from Harvard Medical School. He completed his postgraduate training in Internal Medicine at Brigham & Women's Hospital (MA, USA), followed by a fellowship in Medical Oncology and Hematology at Dana-Farber Cancer Institute. Following additional post-doctoral training in Chemistry at Harvard University and the Broad Institute (MA, USA) with Professor Stuart Schreiber, Bradner joined the research faculty of Dana-Farber in 2008. Interview conducted by Hannah Coaker, Assistant Commissioning Editor.

  10. James Webb Telescope's Near Infrared Camera: Making Models, Building Understanding (United States)

    Lebofsky, Larry A.; McCarthy, D. W.; Higgins, M. L.; Lebofsky, N. R.


    The Astronomy Camp for Girl Scout Leaders is a science education program sponsored by NASA's next large space telescope: The James Webb Space Telescope (JWST). The E/PO team for JWST's Near Infrared Camera (NIRCam), in collaboration with the Sahuaro Girl Scout Council, has developed a long-term relationship with adult leaders from all GSUSA Councils that directly benefits troops of all ages, not only in general science education but also specifically in the astronomical and technology concepts relating to JWST. We have been training and equipping these leaders so they can in turn teach young women essential concepts in astronomy, i.e., the night sky environment. We model what astronomers do by engaging trainers in the process of scientific inquiry, and we equip them to host troop-level astronomy-related activities. It is GSUSA's goal to foster girls’ interest and creativity in Science, Technology, Engineering, and Math, creating an environment that encourages their interests early in their lives while creating a safe place for girls to try and fail, and then try again and succeed. To date, we have trained over 158 leaders in 13 camps. These leaders have come from 24 states, DC, Guam, and Japan. While many of the camp activities are related to the "First Light” theme, many of the background activities relate to two of the other JWST and NIRCam themes: "Birth of Stars and Protoplanetary Systems” and "Planetary Systems and the Origin of Life.” The latter includes our own Solar System. Our poster will highlight the Planetary Systems theme: 1. Earth and Moon: Day and Night; Rotation and Revolution. 2. Earth/Moon Comparisons. 3. Size Model: The Diameters of the Planets. 4. Macramé Planetary (Solar) Distance Model. 5.What is a Planet? 6. Planet Sorting Cards. 7. Human Orrery 8. Lookback Time in Our Daily Lives NIRCam E/PO website: dmccarthy/GSUSA

  11. Obituary: James Alfred Van Allen, 1914-2006 (United States)

    Ludwig, George H.; McIlwain, Carl Edwin


    James Alfred Van Allen, world-renowned space scientist, died 9 August 2006 at the age of ninety-one. He succumbed to heart failure after a ten-week period of declining health. Van Allen served for his entire sixty-seven-year professional career as an amazingly productive researcher, space science spokesman, inspired teacher, and valued colleague. The realization by him and his associates that charged particles are trapped by the Earth's magnetic field began a whole new field of research, magnetospheric physics. Following that initial discovery, he and his associates quickly extended their observations, first to the inner planets, and then to the rest of the planets and beyond. During his tenure at Iowa, he and his group flew instruments on more than sixty successful Earth satellites and planetary spacecraft, including the first missions to the planets Venus, Mars, Jupiter, Saturn, Uranus, and Neptune. Van Allen's lifetime publication list numbers more than 275, of which many are widely-cited, seminal papers. He was the sole author of more than 125 of those papers. Beyond the research laboratory, Van Allen worked energetically throughout his career in establishing space research as a new branch of human inquiry. He was among the most sought-after as a committee member and adviser, working at the highest levels of government, including the White House and Congress, and at all levels of the national and international research establishments. Many presentations in the non-scientific arena helped to bring the exciting discoveries and challenges of space research to the attention of the general public. James Van Allen (Van to his many friends and colleagues) was born on 7 September 1914 on a small farm near Mount Pleasant, Iowa, the second of four sons of Alfred Morris Van Allen and Alma Olney Van Allen. After high school in Mount Pleasant, he entered Iowa Wesleyan College, majoring in physics and graduating summa cum laude. While there, he was introduced to geophysics

  12. Publicações póstumas de Henri Fayol: revisitando sua teoria administrativa.

    Directory of Open Access Journals (Sweden)

    Edson Miranda de Souza


    Full Text Available O engenheiro francês Henri Fayol (1841-1925 é usualmente apresentado aos estudantes de Administração como o Pai da Escola Clássica de Administração, o que demonstra uma representação limitada da amplitude de sua contribuição para a evolução do pensamento administrativo. Além disso, é frequentemente associado ao seu contemporâneo, o teórico norte-americano Frederick Taylor, sendo aos dois atribuída a defesa de um modelo autoritário de administração. Entretanto, recentemente, pesquisadores descobriram, através do exame de documentos raros e inéditos, um desconhecido retrato desse pioneiro. Este trabalho resulta de uma investigação que buscou levantar fontes de informação bibliográfica disponíveis, publicadas ou não, incluindo resultados de trabalhos de pesquisadores da França, dos Estados Unidos, do Canadá, da Austrália e do Japão. Esses pesquisadores compõem um reduzido grupo de estudiosos, aqui denominados “novos fayolistas” porque retomam, depois de anos de quase amnésia no meio acadêmico, o interesse pelas contribuições de Henri Fayol. Tais estudos revelam conceitos desenvolvidos por Fayol que antecipam aspectos de teorias e práticas da Administração que, somente mais tarde, seriam desenvolvidas, como a Escola de Relações Humanas, a Teoria Contingencial e o Planejamento Estratégico. Ao apresentar as recentes pesquisas sobre o homem e o teórico Henri Fayol, este estudo permite, aos docentes e estudantes de língua portuguesa, acesso a escritos e palestras de sua autoria que, até então, permaneciam desconhecidos.

  13. The study of patient henry Molaison and what it taught us over past 50 years: Contributions to neuroscience

    Directory of Open Access Journals (Sweden)

    Bigya Shah


    Full Text Available This section provides a historical perspective and contributions from one of the most studied patients in neuroscience, Henry Molaison (1926-2008, known as H.M during his life to protect his privacy. The peculiar memory deficits seen after an experimental operation for intractable epilepsy led to some critical discoveries pertaining to memory organization in human brain.

  14. All Are Worthy to Know the Earth: Henry De la Beche and the Origin of Geological Literacy (United States)

    Clary, Renee M.; Wandersee, James H.


    Henry T. De la Beche (1796-1855) began his geological career within an elite circle (Geological Society of London, 1817; FRS, 1819), collaborating with influential gentlemen geologists and publishing original research. When his independent income dwindled, De la Beche managed to secure governmental funding for his mapping projects. This led to…

  15. "Undoubtedly a Powerful Influence": Victor Henry's "Antinomies linguistiques" (1896) with an Annotated Translation of the First Chapter. (United States)

    Joseph, John E.


    Discusses Victor Henry's innovative presentation of some underlying contradictions in the premises on which linguistics is founded, cast in the Kantian form of antinomies. The review argues that no science remains more strongly contested than linguistics, a science whose origins are paradoxical and that contains outdated concepts. (30 references)…

  16. Measurement of Henry's Law Constants Using Internal Standards: A Quantitative GC Experiment for the Instrumental Analysis or Environmental Chemistry Laboratory (United States)

    Ji, Chang; Boisvert, Susanne M.; Arida, Ann-Marie C.; Day, Shannon E.


    An internal standard method applicable to undergraduate instrumental analysis or environmental chemistry laboratory has been designed and tested to determine the Henry's law constants for a series of alkyl nitriles. In this method, a mixture of the analytes and an internal standard is prepared and used to make a standard solution (organic solvent)…

  17. The discovery of uranic rays: a short step for Henri Becquerel but a giant step for science

    International Nuclear Information System (INIS)

    Genet, M.


    In March 1896, Antoine Henri Becquerel discovered radioactivity. This success is largely due to a tradition of high-level scientific research which prevailed over three generations in the Becquerel family. The circumstances of the discovery and the controversies which followed are reviewed within the framework of their scientific and historical context. (orig.)

  18. The Therapeutic Use of Fairy Tales with Adults in Group Therapy (United States)

    Brown, Nina W.


    Fairy tales are not just for children. They can hold important messages for people of all ages, as well as for those with special needs. For example, people who present for therapy reporting such issues as fear of abandonment, sibling rivalry, self-esteem, and lack of meaning in life, among others, can benefit from using fairy tales as a…

  19. The Analysis of the Gothic Element--High Emotion in The Tell-tale Heart

    Institute of Scientific and Technical Information of China (English)



    The Tell-tale Heart is one of the most typical gothic novel of Allen Poe’s. This article intends to analyse one of the gothic elements, that is, high emotion which is employed in The Tell-tale Heart to contribute to the horror effect.

  20. The Analysis of the Gothic Element——High Emotion in The Tell-tale Heart

    Institute of Scientific and Technical Information of China (English)



    The Tell-tale Heart is one of the most typical gothic novel of Allen Poe’s. This article intends to analyse one of the gothic elements, that is, high emotion which is employed in The Tell-tale Heart to contribute to the horror effect.

  1. The Ordinary and the Fabulous: An Introduction to Myths, Legends and Fairy Tales. Second Edition. (United States)

    Cook, Elizabeth

    Written for teachers, for students who intend to be teachers or librarians, and for storytellers in general, this book interprets the familiar legends and tales (Greek, Scandinavian, German, and Celtic myths and legends; Arthurian romances; the Old Testament; and fairy tales) and describes how they can best be told to children. Parallel accounts…

  2. Authorial or Scribal? : spelling variation in the Hengwrt and Ellesmere manuscripts of The Canterbury Tales

    NARCIS (Netherlands)

    Caon, Luigina Marina Domenica


    Chaucer’s Canterbury Tales has come down to us in about 80 fifteenth-century manuscripts, none of which is in his own hand. What is conventionally referred to as ‘Chaucer’s language’ is the language found in two early texts of The Canterbury Tales, the Hengwrt and the Ellesmere manuscripts. Despite

  3. A Case Study of Editorial Filters in Folktales: A Discussion of the "Allerleirauh" Tales in Grimm. (United States)

    Dollerup, Cay; And Others


    This article discusses editorial "filters" in folktales, specifically the changes ("orientations") which editors deliberately impose on a tale because they want to reach a specific audience. A case in point is the tale called "Allerleirauh," in the Grimm collection, which not only is highly illustrative of editorial…

  4. Engaging with Mathematics in the Kindergarten. Orchestrating a Fairy Tale through Questioning and Use of Tools (United States)

    Carlsen, Martin


    The aim of this study is to analyse how a kindergarten teacher orchestrated a mathematical activity involving a fairy tale. Taking a sociocultural perspective on learning and development, naturally occurring talk-in-interaction has been analysed in order to scrutinise the subtleties of the orchestration. The fairy tale "Goldilocks and the…

  5. Oral Interpretation of C.S. Lewis'"Narnia Tales": A Refracting of "Pictures." (United States)

    Keefe, Carolyn

    "The Chronicles of Narnia" are a series of seven fairy tales written by C.S. Lewis that have become popular with both children and adults. Lewis points to five aspects of the fairy tale form that made the form suitable for expressing the images he saw. The aspects are: (1) no love interest; (2) no close psychology; (3) severe restraints…

  6. The Historical Analysis of Features of Teaching the Fairy Tale at Elementary School

    Directory of Open Access Journals (Sweden)

    T V Merkuryeva


    Full Text Available The historical analysis of working with fairy-tale material at the lessons of Reading and Literary Reading at elementary school is given in the article. The analytical review of the dissertation themes formulations containing the word «fairy tale» in their title is carried out.

  7. DNA-binding proteins from marine bacteria expand the known sequence diversity of TALE-like repeats. (United States)

    de Lange, Orlando; Wolf, Christina; Thiel, Philipp; Krüger, Jens; Kleusch, Christian; Kohlbacher, Oliver; Lahaye, Thomas


    Transcription Activator-Like Effectors (TALEs) of Xanthomonas bacteria are programmable DNA binding proteins with unprecedented target specificity. Comparative studies into TALE repeat structure and function are hindered by the limited sequence variation among TALE repeats. More sequence-diverse TALE-like proteins are known from Ralstonia solanacearum (RipTALs) and Burkholderia rhizoxinica (Bats), but RipTAL and Bat repeats are conserved with those of TALEs around the DNA-binding residue. We study two novel marine-organism TALE-like proteins (MOrTL1 and MOrTL2), the first to date of non-terrestrial origin. We have assessed their DNA-binding properties and modelled repeat structures. We found that repeats from these proteins mediate sequence specific DNA binding conforming to the TALE code, despite low sequence similarity to TALE repeats, and with novel residues around the BSR. However, MOrTL1 repeats show greater sequence discriminating power than MOrTL2 repeats. Sequence alignments show that there are only three residues conserved between repeats of all TALE-like proteins including the two new additions. This conserved motif could prove useful as an identifier for future TALE-likes. Additionally, comparing MOrTL repeats with those of other TALE-likes suggests a common evolutionary origin for the TALEs, RipTALs and Bats. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  8. James Chadwick Nobel Prize for Physics 1935. Discovery of the neutron; James Chadwick Premio Nobel de Fisica 1935. Descubrimiento del neutron

    Energy Technology Data Exchange (ETDEWEB)



    James Chadwick (1981-1974) was a key figure in the field of nuclear science. Through his studies, he researched the disintegration of atoms by bombarding alpha particles and proved the existence of neutrons. For this discovery, he was awarded the Nobel Prize for physics in 1935. (Author)

  9. Design of a gap tunable flux qubit with FastHenry (United States)

    Akhtar, Naheed; Zheng, Yarui; Nazir, Mudassar; Wu, Yulin; Deng, Hui; Zheng, Dongning; Zhu, Xiaobo


    In the preparations of superconducting qubits, circuit design is a vital process because the parameters and layout of the circuit not only determine the way we address the qubits, but also strongly affect the qubit coherence properties. One of the most important circuit parameters, which needs to be carefully designed, is the mutual inductance among different parts of a superconducting circuit. In this paper we demonstrate how to design a gap-tunable flux qubit by layout design and inductance extraction using a fast field solver FastHenry. The energy spectrum of the gap-tunable flux qubit shows that the measured parameters are close to the design values. Project supported by the National Natural Science Foundation of China (Grant Nos. 11374344, 11404386, and 91321208), the National Basic Research Program of China (Grant No. 2014CB921401), and the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No. XDB07010300).

  10. Henri Mitterand – Critique génétique et sociocritique


    Mitterand, Henri; Biasi, Pierre-Marc de; Herschberg Pierrot, Anne


    Henri Mitterand est l’un des fondateurs de la sociocritique en France, et de la génétique zolienne. Il est aussi linguiste, sémioticien et stylisticien. Nous l’avons interrogé sur les relations complexes de la génétique et de la sociocritique. Sociocritique et sociogenèse Pierre-Marc de Biasi – Après une trentaine d’années de recul et d’expérience, quelle place donneriez-vous à la sociocritique et à la sociogenèse dans la construction du nouveau rapport critique qui s’est institué avec les ma...

  11. The Right to the City: From Henri Lefebvre to the Analysis about the Contemporary Capitalist City

    Directory of Open Access Journals (Sweden)

    Frank Molano Camargo


    Full Text Available The right to the city, defined by Henri Lefebvre in 1967 as the right of urban inhabitants to build, decide and create the city, and make of it a privileged space of anti-capitalist struggle, is again at the center of political debate. Social scientists, social movements, international aid agencies and States take it as a benchmark for policy analysis and to discuss the urban changes in contemporary capitalist cities. This article discusses the assumptions made by Lefebvre in 1967 and the transformation that the concept of right to the city has had from authors such as David Harvey, Edward Soja and Ana Fani Alessandri Carlos.

  12. About Time. Physics, Philosophy and the Battle Between Albert Einstein and Henri Bergson (United States)

    Frank, Adam

    The historical relationship between physics and philosophy has had many famous high and low points. The two function best when both can challenge and support each other. In this talk I explore the famous debate between Albert Einstein and Henri Bergson over the nature of time. While history rightly judged Einstein to have won the debate in terms of relativity, there were deeper aspects of Bergsons critique that remain unappreciated. We will explore the different ways philosophy approaches the issue of time. In particular, we will look at the Continental Schools\\x9D, such as Phenomenology, which brings a unique perspective to the debate lying outside the traditional approach of physicists. From this perspective questions related to the act of being an observer, its essential subjective nature and the proper context of physics can be explored.

  13. Review: Henry E. Brady & David Collier (Eds. (2004. Rethinking Social Inquiry: Diverse Tools, Shared Standards

    Directory of Open Access Journals (Sweden)

    Matthias Catón


    Full Text Available The book Rethinking Social Inquiry, edited by Henry E. BRADY and David COLLIER, is a response to a book by KING, KEOHANE and VERBA (1994 that aimed to introduce quantitative standards to qualitative research. The authors of the book reviewed here criticize many of the suggestions made there because they argue that qualitative research requires other tools. Nevertheless, they agree that the foundations of research design are similar. The book comprises a comprehensive critique of mainstream quantitative techniques, describes a set of qualitative tools for research, and addresses issues of how to combine qualitative and quantitative approaches to maximize analytical leverage. It is an excellent contribution to the methodological debate in the social sciences. URN: urn:nbn:de:0114-fqs0602309

  14. Henry Moore’s Public Sculpture in the US: The Collaborations with I. M. Pei

    Directory of Open Access Journals (Sweden)

    Alex Potts


    Full Text Available The many commissions Henry Moore received for public sculpture in the United States provided the occasion for several quite distinctive works. While not site specific, these were unique, and their final form, scale, and disposition was elaborated with a particular setting in mind. This aspect of Moore’s work in the US, which began with the monumental piece he designed for the Lincoln Center in New York in 1963–65, is examined here by focusing on the productive relationship he forged with the architect I. M. Pei in the 1970s. The sculptures Moore produced in collaboration with Pei respond in suggestive ways to the spatial environments created in American cities by late modern architectural developments. They also realize an oddly effective combination of the biomorphic and abstract that differs both from the bodily conception of Moore’s earlier work and the non-figurative character of much public sculpture of the time.

  15. New Hypersonic Shock Tunnel at the Laboratory of Aerothermodynamics and Hypersonics Prof. Henry T. Nagamatsu

    International Nuclear Information System (INIS)

    Toro, P. G. P.; Minucci, M. A. S.; Chanes, J. B. Jr; Oliveira, A. C.; Gomes, F. A. A.; Myrabo, L. N.; Nagamatsu, Henry T.


    The new 0.60-m. nozzle exit diameter hypersonic shock tunnel was designed to study advanced air-breathing propulsion system such as supersonic combustion and/or laser technologies. In addition, it may be used for hypersonic flow studies and investigations of the electromagnetic (laser) energy addition for flow control. This new hypersonic shock tunnel was designed and installed at the Laboratory for of Aerothermodynamics and Hypersonics Prof. Henry T. Nagamatsu, IEAv-CTA, Brazil. The design of the tunnel enables relatively long test times, 2-10 milliseconds, suitable for the experiments performed at the laboratory. Free stream Mach numbers ranging from 6 to 25 can be produced and stagnation pressures and temperatures up to 360 atm. and up to 9,000 K, respectively, can be generated. Shadowgraph and schlieren optical techniques will be used for flow visualization

  16. Fordlândia e Belterra: as cidades de Henry Ford na Amazônia


    Duarte Jr., Antonio Marcos; UERJ & Ibmec/RJ


    Ao final de 1945, a Ford Motor Company apresenta sérios problemas de gestão. Nesse contexto, Henry Ford II precisa decidir o que fazer com Fordlândia e Belterra, as duas problemáticas cidades construídas por seu avô na Amazônia brasileira.O caso foi elaborado para utilização em disciplinas na área de finanças corporativas, abordando temas relacionados a análise econômica e de riscos presentes em projetos de investimento.  Pode ser interessante também em diferentes disciplinas que tratem de te...

  17. Publicações póstumas de Henri Fayol: revisitando sua teoria administrativa


    Souza, Edson Miranda De; Aguiar, Afrânio Carvalho


    O engenheiro francês Henri Fayol (1841-1925) é usualmente apresentado aos estudantes de Administração como o Pai da Escola Clássica de Administração, o que demonstra uma representação limitada da amplitude de sua contribuição para a evolução do pensamento administrativo. Além disso, é frequentemente associado ao seu contemporâneo, o teórico norte-americano Frederick Taylor, sendo aos dois atribuída a defesa de um modelo autoritário de administração. Entretanto, recentemente, pesquisadores des...

  18. The Allison V. Armour / William Henry Holmes 1895 Expedition to Mexico

    Directory of Open Access Journals (Sweden)

    Warren Haskin


    Full Text Available The foundation of the Field Museum's reputation as a place where serious science is practiced was laid by Allison V. Armour and William Henry Holmes in 1895, a little more than a year after the Museum was established. Looking back after a career of almost 60 years as an anthropologist, and having twice been honored as the outstanding practitioner in the field, Holmes described the trip to Mexico (the only expedition he led during his brief tenure as the Museum's first Curator of An­thropology as "one of the most gratifying and important events of my life." It was also one of the most important events in the history of anthropology at the Museum.

  19. Samuel Hartlib on the death of Descartes: a rediscovered letter to Henry More (United States)

    Penman, Leigh T. I.


    This paper discloses the content of a previously overlooked epistle by the Anglo-Prussian intelligencer Samuel Hartlib to Henry More concerning the death of René Descartes. After a discussion situating the letter within the sequence of the More–Hartlib correspondence, an analysis of the rhetorical structure of the epistle is offered, followed by a brief assessment of Hartlib's attitude towards Descartes, and the identification of his source concerning the news of the philosopher's death. An account of the transmission of the letter via a nineteenth-century periodical is also provided. The text of Hartlib's letter and an overlooked passage of Hartlib's diary concerning Descartes's death, which draws on the content of the More letter, are presented as appendixes.

  20. Publicações póstumas de Henri Fayol: revisitando sua teoria administrativa.


    Edson Miranda de Souza; Afrânio Carvalho Aguiar


    O engenheiro francês Henri Fayol (1841-1925) é usualmente apresentado aos estudantes de Administração como o Pai da Escola Clássica de Administração, o que demonstra uma representação limitada da amplitude de sua contribuição para a evolução do pensamento administrativo. Além disso, é frequentemente associado ao seu contemporâneo, o teórico norte-americano Frederick Taylor, sendo aos dois atribuída a defesa de um modelo autoritário de administração. Entretanto, recentemente, pesquisadores des...

  1. Anarchism and homosexuality in Wilhelmine Germany: Senna Hoy, Erich Mühsam, John Henry Mackay. (United States)

    Fähnders, W


    Homosexuality and its social and legal suppression were heatedly discussed in early twentieth-century Germany, including on the left. Among the anarchists, positions with markedly diverse forms of argument were espoused by such prominent advocates of individualist anarchism as John Henry Mackay and by others coming from the Bakuninist tradition, such as Senna Hoy and Erich Mühsam. Their writings evidence that prior to World War I and into the 1920s, German anarchists--especially when compared with the Social Democrats--intervened consistently on behalf of individual self-determination extending into the sexual sphere, even though an undercurrent of hostility toward homosexuals persisted within the leftist movement as a whole.

  2. Preliminary assessment report for Fort William Henry Harrison, Montana Army National Guard, Helena, Montana

    International Nuclear Information System (INIS)

    DuWaldt, J.; Meyer, T.


    This report presents the results of the preliminary assessment (PA) conducted by Argonne National Laboratory at a Montana Army National Guard (MTARNG) property near Helena, Montana. Preliminary assessments of federal facilities are being conducted to compile the information necessary for completing preremedial activities and to provide a basis for establishing corrective actions in response to releases of hazardous substances. The principal objective of the PA is to characterize the site accurately and determine the need for further action by examining site activities, quantities of hazardous substances present, and potential pathways by which contamination could affect public health and the environment. This PA satisfies, for the Fort William Henry Harrison property, requirements of the Department of Defense Installation Restoration Program


    Jenkins, Bill


    Evidence for the transformist ideas espoused by Henry H. Cheek (1807-33), a contemporary of Charles Darwin's at the University of Edinburgh, sheds new light on the intellectual environment of Edinburgh in the late 1820s and early 1830s. Cheek was the author of several papers dealing with the transmutation of species influenced by the theories of Etienne Geoffroy Saint-Hilaire (1772-1844), Jean-Baptiste Lamarck (1744-1829) and the Comte de Buffon (1707-88). Some of these were read to student societies, others appeared in the Edinburgh Journal of Natural and Geographical Science, which Cheek edited between 1829 and 1831. His writings give us a valuable window onto some of the transformist theories that were circulating among Darwin's fellow medical students in the late 1820s, to which Darwin would have been exposed during his time in Edinburgh, and for which little other concrete evidence survives.

  4. How the Other Half Lives: Under the Arch with Lady Henry Somerset

    Directory of Open Access Journals (Sweden)

    Paisana Joanne


    Full Text Available The reforming work of Isabella Caroline Somerset (Lady Henry Somerset 1851-1921 is largely overlooked today. Dedicated to women’s causes at home and abroad and to temperance in particular, having first-hand knowledge of the privileged and the underprivileged, this determined, multi-talented and opinionated woman uncharacteristically wrote a fictional novel, Under the Arch (1906. In the novel, London aristocrats are portrayed rubbing shoulders with slum dwellers, but there is little real connection. The problems that the social policies introduced by the Liberals from 1906-1914 would address are nevertheless highlighted. It can be no coincidence that Somerset was well acquainted with many of these politicians. The themes of relieving the poor, Christian doctrine, marriage, women’s suffrage and imperialism are addressed, although Somerset’s focus is simply on “doing good” and loving one’s neighbour

  5. Genealogía de la conciencia en la filosofía de Henri Bergson


    Urquijo Reguera, Mariana


    Esta investigación se propone mostrar la concepción de la conciencia de Henri Bergson (1859-1941) a través de una lectura crítica de su filosofía. El análisis recorre los textos del autor exponiendo su filosofía de la duración, frente a la filosofía que piensa en el espacio. El objetivo de este estudio ha sido demostrar la vigencia de su filosofía de cara a un diálogo con la ciencia contemporánea, su actualidad para pensar lso problemas filosóficos y los problemas contemporáneos. Partiendo d...

  6. Improved specificity of TALE-based genome editing using an expanded RVD repertoire. (United States)

    Miller, Jeffrey C; Zhang, Lei; Xia, Danny F; Campo, John J; Ankoudinova, Irina V; Guschin, Dmitry Y; Babiarz, Joshua E; Meng, Xiangdong; Hinkley, Sarah J; Lam, Stephen C; Paschon, David E; Vincent, Anna I; Dulay, Gladys P; Barlow, Kyle A; Shivak, David A; Leung, Elo; Kim, Jinwon D; Amora, Rainier; Urnov, Fyodor D; Gregory, Philip D; Rebar, Edward J


    Transcription activator-like effector (TALE) proteins have gained broad appeal as a platform for targeted DNA recognition, largely owing to their simple rules for design. These rules relate the base specified by a single TALE repeat to the identity of two key residues (the repeat variable diresidue, or RVD) and enable design for new sequence targets via modular shuffling of these units. A key limitation of these rules is that their simplicity precludes options for improving designs that are insufficiently active or specific. Here we address this limitation by developing an expanded set of RVDs and applying them to improve the performance of previously described TALEs. As an extreme example, total conversion of a TALE nuclease to new RVDs substantially reduced off-target cleavage in cellular studies. By providing new RVDs and design strategies, these studies establish options for developing improved TALEs for broader application across medicine and biotechnology.

  7. A transcription activator-like effector (TALE) induction system mediated by proteolysis. (United States)

    Copeland, Matthew F; Politz, Mark C; Johnson, Charles B; Markley, Andrew L; Pfleger, Brian F


    Simple and predictable trans-acting regulatory tools are needed in the fields of synthetic biology and metabolic engineering to build complex genetic circuits and optimize the levels of native and heterologous gene products. Transcription activator-like effectors (TALEs) are bacterial virulence factors that have recently gained traction in biotechnology applications owing to their customizable DNA-binding specificity. In this work we expanded the versatility of these transcription factors to create an inducible TALE system by inserting tobacco-etch virus (TEV) protease recognition sites into the TALE backbone. The resulting engineered TALEs maintain transcriptional repression of their target genes in Escherichia coli, but are degraded after induction of the TEV protease, thereby promoting expression of the previously repressed target gene of interest. This TALE-TEV technology enables both repression and induction of plasmid or chromosomal target genes in a manner analogous to traditional repressor proteins but with the added flexibility of being operator-agnostic.

  8. Comprehensive Interrogation of Natural TALE DNA Binding Modules and Transcriptional Repressor Domains (United States)

    Cong, Le; Zhou, Ruhong; Kuo, Yu-chi; Cunniff, Margaret; Zhang, Feng


    Transcription activator-like effectors (TALE) are sequence-specific DNA binding proteins that harbor modular, repetitive DNA binding domains. TALEs have enabled the creation of customizable designer transcriptional factors and sequence-specific nucleases for genome engineering. Here we report two improvements of the TALE toolbox for achieving efficient activation and repression of endogenous gene expression in mammalian cells. We show that the naturally occurring repeat variable diresidue (RVD) Asn-His (NH) has high biological activity and specificity for guanine, a highly prevalent base in mammalian genomes. We also report an effective TALE transcriptional repressor architecture for targeted inhibition of transcription in mammalian cells. These findings will improve the precision and effectiveness of genome engineering that can be achieved using TALEs. PMID:22828628

  9. A TALE-inspired computational screen for proteins that contain approximate tandem repeats. (United States)

    Perycz, Malgorzata; Krwawicz, Joanna; Bochtler, Matthias


    TAL (transcription activator-like) effectors (TALEs) are bacterial proteins that are secreted from bacteria to plant cells to act as transcriptional activators. TALEs and related proteins (RipTALs, BurrH, MOrTL1 and MOrTL2) contain approximate tandem repeats that differ in conserved positions that define specificity. Using PERL, we screened ~47 million protein sequences for TALE-like architecture characterized by approximate tandem repeats (between 30 and 43 amino acids in length) and sequence variability in conserved positions, without requiring sequence similarity to TALEs. Candidate proteins were scored according to their propensity for nuclear localization, secondary structure, repeat sequence complexity, as well as covariation and predicted structural proximity of variable residues. Biological context was tentatively inferred from co-occurrence of other domains and interactome predictions. Approximate repeats with TALE-like features that merit experimental characterization were found in a protein of chestnut blight fungus, a eukaryotic plant pathogen.

  10. Henry Solomon Wellcome: A philanthropist and a pioneer sponsor of medical research in the Sudan. (United States)

    Adeel, Ahmed Awad A


    Henry Solomon Wellcome, the famous drug manufacturer had a fascinating association with the Sudan. Besides supporting tropical medicine research in this country, he established an extensive project in the Sudan that aimed at combining archeological excavations, philanthropy and social reform. This article is an archives-based account on this side of Wellcome's association with the Sudan. The article starts with Wellcome's early years in the American Midwest and the evolution of his career and his rise as a world-renowned drug manufacturer. After the battle of Omdurman, Wellcome visited Sudan in 1900 - 1901 where he offered to support the establishment of the research laboratories which later came to be known as the Wellcome Tropical Research Laboratories in Khartoum. He then became directly involved in the planning and running of extensive archeological excavations in the central Sudan. This project served as a field in which Wellcome found an outlet for his philanthropy. More than 4000 labourers were employed in Jebel Moya. Professional archeologists and anatomists were recruited by Wellcome to supervise the work, and all the requirements in terms of equipment were catered for. Wellcome devised a Savings Bank System whereby part of the earnings of each labourer were saved to him till the end of the season. He also introduced one of his innovations: aerial photography using box kite which was used for the first time in archeology. Wellcome made it a rule that no applicant should be turned away. The Camp Commandant had to find suitable work for each applicant, including the handicapped who were assigned to appropriate jobs like mending baskets or cutting grass for building huts. Wellcome's welfare work had a significant impact on the local inhabitants of Jebel Moya. Henry Solomon Wellcome, 1906. Oil painting by Hugh Goldwin Riviere. Credit: Wellcome Library.

  11. Style and non-style in anatomical illustration: From Renaissance Humanism to Henry Gray. (United States)

    Kemp, Martin


    Style is a familiar category for the analysis of art. It is less so in the history of anatomical illustration. The great Renaissance and Baroque picture books of anatomy illustrated with stylish woodcuts and engravings, such as those by Charles Estienne, Andreas Vesalius and Govard Bidloo, showed figures in dramatic action in keeping with philosophical and theological ideas about human nature. Parallels can be found in paintings of the period, such as those by Titian, Michelangelo and Hans Baldung Grien. The anatomists also claimed to portray the body in an objective manner, and showed themselves as heroes of the discovery of human knowledge. Rembrandt's painting of Dr Nicholas Tulp is the best-known image of the anatomist as hero. The British empirical tradition in the 18th century saw William Cheselden and William Hunter working with techniques of representation that were intended to guarantee detailed realism. The ambition to portray forms life-size led to massive volumes, such as those by Antonio Mascagni. John Bell, the Scottish anatomist, criticized the size and pretensions of the earlier books and argued for a plain style adapted to the needs of teaching and surgery. Henry Gray's famous Anatomy of 1858, illustrated by Henry Vandyke Carter, aspired to a simple descriptive mode of functional representation that avoided stylishness, resulting in a style of its own. Successive editions of Gray progressively saw the replacement of Gray's method and of all his illustrations. The 150th anniversary edition, edited by Susan Standring, radically re-thinks the role of Gray's book within the teaching of medicine.

  12. Never say Never. About the Restoration of Henry van de Velde’s Booktower

    Directory of Open Access Journals (Sweden)

    Sylvia van Peteghem


    Full Text Available The role of the central library within the university of Ghent (27.000 students is fourfold: it is the centre of the library’s network and its reorganisation, trying to get the current number (> 300 of libraries down. It is the digital library in all its aspects, it is the repository library for cultural heritage and “passive” collections and it offers a working place in its wonderful book tower of Henry van de Velde. The story of the book tower starts in the 1930s when Henry van de Velde was asked to build a University Library and offices for the department of Art history. His tower-idea was not exactly what the chief librarian had in mind, so he had to (network hard to get the building he wanted. It was finished on the verge of the second world war. The concrete building has a height of 64 meter, has 24 floors and a “belvedere” and houses almost 3 million books in closed racks. The university did not neglect the tower during all these years, but was not always aware of the historical value and often choose the cheapest way for building matters. A couple of years ago a private person bought the Van de Velde archive of the book tower (which was in private hands, got fascinated with the building, got angry because of lack of care and networked (maybe as hard as Van de Velde once did to get it built to get it restored. The board of directors of the university said yes to the restoration (estimated on 41 million Euro in September 2005.

  13. Karen W. Tice, Tales of Wayward Girls and Immoral Women


    Niget, David


    Tales of Wayward Girls and Immoral Women : Case Records and the Professionalization of Social Work Karen W. Tice Chicago, University of Illinois Press, 1998, 272 p. ISBN: 0252023978 Cet ouvrage n’est ni une étude de socio-histoire des professions sociales, ni une monographie des populations vulnérables prises en charge par les agences sociales qui se multiplient au début du XXe siècle en Amérique du Nord. Karen Tice, enseignante en sciences de l’éducation et en études féministes, a adopté un...

  14. Narrating Organisational Identities by Way of Evolutionary Tales

    DEFF Research Database (Denmark)

    Backer, Lise


    The article draws on publicly available data to analyse how, since the Rio Environmental Summit in 1992, the narration of the multinational oil company Shell have projected an evolution from an oil company identity to an identity also embracing renewable energies. In analysing the narrative battles...... over Shell's organisational identity the article contributes to the field of organisational identity theory. It does so by providing a rich description of the micro processes through which individual management actors seek by telling different evolutionary tales to get the larger corporate actor...

  15. There and back again: a T-brane’s tale

    International Nuclear Information System (INIS)

    Bena, Iosif; Blåbäck, Johan; Minasian, Ruben; Savelli, Raffaele


    T-branes are supersymmetric configurations described by multiple Dp-branes with worldvolume flux and non-commuting vacuum expectation values for two of the worldvolume scalars. When these values are much larger than the string scale this description breaks down. We show that in this regime the correct description of T-branes is in terms of a single Dp-brane, whose worldvolume curvature encodes the T-brane data. We present the tale of the journey to reach this picture, which takes us through T-dualities and rugby-ball-shaped brane configurations that no eye has gazed upon before.

  16. There and back again: a T-brane’s tale

    Energy Technology Data Exchange (ETDEWEB)

    Bena, Iosif; Blåbäck, Johan; Minasian, Ruben; Savelli, Raffaele [Institut de Physique Théorique, Université Paris Saclay, CEA, CNRS,Orme des Merisiers, F-91191 Gif-sur-Yvette (France)


    T-branes are supersymmetric configurations described by multiple Dp-branes with worldvolume flux and non-commuting vacuum expectation values for two of the worldvolume scalars. When these values are much larger than the string scale this description breaks down. We show that in this regime the correct description of T-branes is in terms of a single Dp-brane, whose worldvolume curvature encodes the T-brane data. We present the tale of the journey to reach this picture, which takes us through T-dualities and rugby-ball-shaped brane configurations that no eye has gazed upon before.

  17. Tall Tales: The Simpsons deconstructing the american myth

    Directory of Open Access Journals (Sweden)

    Hanna Betina Götz


    Full Text Available This article aims to analyze the episode Tall Tales from the series The Simpsons that revisits legends of the American folklore. The TV series pays homage to both the time of the pioneers in their travels to the Far West in the nineteenth century, as well as to one of the most iconic and folk characters of the American culture from that period: the Hobo was a beggar, a figure of the American folklore during the Great Depression. It is also interesting to focus on the American imaginary in order to understand how the authors of The Simpsons perform these recreations in contemporary times

  18. The ethics of heroism in medieval and American Indian tales. (United States)

    Scott, A


    Oral-traditional stories detail their heroes' growth through a narrative pattern of exile and return that places the heroes in situations repeatedly challenging their strength and resolve. Through the motif of the quest, medieval and American Indian tales alike reaffirm general psychological truths that bear upon our understanding of human nature. Stories about heroes are stories about us: about our desires to grow up, to defeat death, to prove ourselves in difficult situations, and to achieve recognition or admiration among our peers (Becker, 1973, p. 4). In this way, medieval and American Indian tales are about self-actualization. They maintain that "one has within oneself proclivity toward growth and unity of personality ... and an automatic thrust toward expression" of these qualities (Yalom, 1980, p. 9). All forms of literature, however, reflect ideas peculiar to their cultures. The ways in which these basic human truths are represented in medieval and American Indian tales suggest the differing religious or social concerns that have informed these truths and have given them shape. To a large degree, the medieval knight's view of "self" and "other" encompasses the view that Western humanity has had (and continues to have) of itself. This is a view conditioned upon the superiority of the "self" as measured against the inferiority of the "other," reinforced through existing social (hierarchial) and religious (Judeo-Christian) codes of behavior. Such codes are not only inadequate to the task of interpreting American Indian perceptions of "self" and "other," they are inimical to the ethical foundation underlying them. Scott Momaday remarks that "you cannot understand how the Indian thinks of himself in relation to the world around him unless you understand his conception of what is appropriate; particularly what is morally appropriate within the context of that relationship" (Basso, 1984, p. 46). For the American Indian hero, self-actualization is self

  19. A simple and efficient method for assembling TALE protein based on plasmid library. (United States)

    Zhang, Zhiqiang; Li, Duo; Xu, Huarong; Xin, Ying; Zhang, Tingting; Ma, Lixia; Wang, Xin; Chen, Zhilong; Zhang, Zhiying


    DNA binding domain of the transcription activator-like effectors (TALEs) from Xanthomonas sp. consists of tandem repeats that can be rearranged according to a simple cipher to target new DNA sequences with high DNA-binding specificity. This technology has been successfully applied in varieties of species for genome engineering. However, assembling long TALE tandem repeats remains a big challenge precluding wide use of this technology. Although several new methodologies for efficiently assembling TALE repeats have been recently reported, all of them require either sophisticated facilities or skilled technicians to carry them out. Here, we described a simple and efficient method for generating customized TALE nucleases (TALENs) and TALE transcription factors (TALE-TFs) based on TALE repeat tetramer library. A tetramer library consisting of 256 tetramers covers all possible combinations of 4 base pairs. A set of unique primers was designed for amplification of these tetramers. PCR products were assembled by one step of digestion/ligation reaction. 12 TALE constructs including 4 TALEN pairs targeted to mouse Gt(ROSA)26Sor gene and mouse Mstn gene sequences as well as 4 TALE-TF constructs targeted to mouse Oct4, c-Myc, Klf4 and Sox2 gene promoter sequences were generated by using our method. The construction routines took 3 days and parallel constructions were available. The rate of positive clones during colony PCR verification was 64% on average. Sequencing results suggested that all TALE constructs were performed with high successful rate. This is a rapid and cost-efficient method using the most common enzymes and facilities with a high success rate.

  20. XML: James Webb Space Telescope Database Issues, Lessons, and Status (United States)

    Detter, Ryan; Mooney, Michael; Fatig, Curtis


    This paper will present the current concept using extensible Markup Language (XML) as the underlying structure for the James Webb Space Telescope (JWST) database. The purpose of using XML is to provide a JWST database, independent of any portion of the ground system, yet still compatible with the various systems using a variety of different structures. The testing of the JWST Flight Software (FSW) started in 2002, yet the launch is scheduled for 2011 with a planned 5-year mission and a 5-year follow on option. The initial database and ground system elements, including the commands, telemetry, and ground system tools will be used for 19 years, plus post mission activities. During the Integration and Test (I&T) phases of the JWST development, 24 distinct laboratories, each geographically dispersed, will have local database tools with an XML database. Each of these laboratories database tools will be used for the exporting and importing of data both locally and to a central database system, inputting data to the database certification process, and providing various reports. A centralized certified database repository will be maintained by the Space Telescope Science Institute (STScI), in Baltimore, Maryland, USA. One of the challenges for the database is to be flexible enough to allow for the upgrade, addition or changing of individual items without effecting the entire ground system. Also, using XML should allow for the altering of the import and export formats needed by the various elements, tracking the verification/validation of each database item, allow many organizations to provide database inputs, and the merging of the many existing database processes into one central database structure throughout the JWST program. Many National Aeronautics and Space Administration (NASA) projects have attempted to take advantage of open source and commercial technology. Often this causes a greater reliance on the use of Commercial-Off-The-Shelf (COTS), which is often limiting

  1. TALE and Shape: How to Make a Leaf Different. (United States)

    Di Giacomo, Elisabetta; Iannelli, Maria Adelaide; Frugis, Giovanna


    The Three Amino acid Loop Extension (TALE) proteins constitute an ancestral superclass of homeodomain transcription factors conserved in animals, plants and fungi. In plants they comprise two classes, KNOTTED1-LIKE homeobox (KNOX) and BEL1-like homeobox (BLH or BELL, hereafter referred to as BLH), which are involved in shoot apical meristem (SAM) function, as well as in the determination and morphological development of leaves, stems and inflorescences. Selective protein-protein interactions between KNOXs and BLHs affect heterodimer subcellular localization and target affinity. KNOXs exert their roles by maintaining a proper balance between undifferentiated and differentiated cell state through the modulation of multiple hormonal pathways. A pivotal function of KNOX in evolutionary diversification of leaf morphology has been assessed. In the SAM of both simple- and compound-leafed seed species, downregulation of most class 1 KNOX (KNOX1) genes marks the sites of leaf primordia initiation. However, KNOX1 expression is re-established during leaf primordia development of compound-leafed species to maintain transient indeterminacy and morphogenetic activity at the leaf margins. Despite the increasing knowledge available about KNOX1 protein function in plant development, a comprehensive view on their downstream effectors remains elusive. This review highlights the role of TALE proteins in leaf initiation and morphological plasticity with a focus on recent advances in the identification of downstream target genes and pathways.

  2. Comic book tells the tale of Dark Matter

    CERN Multimedia

    Katarina Anthony


    The sciences star in few comic books. On occasion, the comic narrative may feature a villain using science for his nefarious deeds. Or perhaps the hero will have a wild-haired scientific genius for his sidekick. But you wouldn’t expect to read a comic about science news, and you certainly wouldn’t expect that news to be about particle physics. That is, unless you’ve read True Tales.   Released in May 2011, the True Tales comic series tackles complicated physics through simple illustrations. The brainchild of Daniel Whiteson – a member of the ATLAS collaboration and an assistant professor at the University of California, Irvine - the comic book depicts the complex topics being studied at CERN, tackling dark matter in its first issue. “Deciding to explain particle physics in a comic book was the easy part,” he explains. “After all, what’s a Feynman diagram but a technical comic strip? The only issue was finding an artis...

  3. Little Book, Big Waves: The Epistle of James and Global Stewardship in Bioethics

    Directory of Open Access Journals (Sweden)

    Lora Jean Brake


    Full Text Available At first glance the twenty-first century arena of biotechnology and bioethics seems worlds away from the practical concerns of the first century outlook of the New Testament book of James. A closer look, however, reveals that the issues that James addresses have applications to challenges in bioethics. This article will give an overview of James and examine James’ teaching on wealth, poverty, and generosity and its import for the issue of global stewardship in bioethics.  Stewardship concerns both a Christian’s care and management of time, talents, and treasures.  Faithful use of the resources God has given demonstrates the fruitful faith that James writes of in his epistle. The idea of global stewardship, though “stewardship” is grounded in a distinctly Christian ethic, reflects an emerging discussion in bioethics regarding the need to address the inequities present between the money and time spent on biotechnology in some of the world in proportion to the money spent on meeting the basic healthcare needs of the poor of the entire world.  This New Testament epistle gives clear indications of how the Christian is to view wealth and how the Christian is to respond to poverty.  James, though a comparatively small book, sends a crucial message across the years that should greatly impact how Christians view stewardship in terms of global healthcare needs. 

  4. Context influences on TALE-DNA binding revealed by quantitative profiling. (United States)

    Rogers, Julia M; Barrera, Luis A; Reyon, Deepak; Sander, Jeffry D; Kellis, Manolis; Joung, J Keith; Bulyk, Martha L


    Transcription activator-like effector (TALE) proteins recognize DNA using a seemingly simple DNA-binding code, which makes them attractive for use in genome engineering technologies that require precise targeting. Although this code is used successfully to design TALEs to target specific sequences, off-target binding has been observed and is difficult to predict. Here we explore TALE-DNA interactions comprehensively by quantitatively assaying the DNA-binding specificities of 21 representative TALEs to ∼5,000-20,000 unique DNA sequences per protein using custom-designed protein-binding microarrays (PBMs). We find that protein context features exert significant influences on binding. Thus, the canonical recognition code does not fully capture the complexity of TALE-DNA binding. We used the PBM data to develop a computational model, Specificity Inference For TAL-Effector Design (SIFTED), to predict the DNA-binding specificity of any TALE. We provide SIFTED as a publicly available web tool that predicts potential genomic off-target sites for improved TALE design.

  5. TALE factors use two distinct functional modes to control an essential zebrafish gene expression program. (United States)

    Ladam, Franck; Stanney, William; Donaldson, Ian J; Yildiz, Ozge; Bobola, Nicoletta; Sagerström, Charles G


    TALE factors are broadly expressed embryonically and known to function in complexes with transcription factors (TFs) like Hox proteins at gastrula/segmentation stages, but it is unclear if such generally expressed factors act by the same mechanism throughout embryogenesis. We identify a TALE-dependent gene regulatory network (GRN) required for anterior development and detect TALE occupancy associated with this GRN throughout embryogenesis. At blastula stages, we uncover a novel functional mode for TALE factors, where they occupy genomic DECA motifs with nearby NF-Y sites. We demonstrate that TALE and NF-Y form complexes and regulate chromatin state at genes of this GRN. At segmentation stages, GRN-associated TALE occupancy expands to include HEXA motifs near PBX:HOX sites. Hence, TALE factors control a key GRN, but utilize distinct DNA motifs and protein partners at different stages - a strategy that may also explain their oncogenic potential and may be employed by other broadly expressed TFs. © 2018, Ladam et al.

  6. Line of Sight Stabilization of James Webb Space Telescope (United States)

    Meza, Luis; Tung, Frank; Anandakrishnan, Satya; Spector, Victor; Hyde, Tupper


    The James Webb Space Telescope (JWST) builds upon the successful flight experience of the Chandra Xray Telescope by incorporating an additional LOS pointing servo to meet the more stringent pointing requirements. The LOS pointing servo, referred to in JWST as the Fine Guidance Control System (FGCS), will utilize a Fine Guidance Sensor (FGS) as the sensor, and a Fine Steering Mirror (FSM) as the actuator. The FSM is a part of the Optical Telescope Element (OTE) and is in the optical path between the tertiary mirror and the instrument focal plane, while the FGS is part of the Integrated Science Instrument Module (ISIM). The basic Chandra spacecraft bus attitude control and determination architecture, utilizing gyros, star trackers/aspect camera, and reaction wheels, is retained for JWST. This system has achieved pointing stability of better than 0.5 arcseconds. To reach the JWST requirements of milli-arcsecond pointing stability with this ACS hardware, the local FGCS loop is added to the optical path. The FGCS bandwidth is about 2.0 Hz and will therefore attenuate much of the spacecraft ACS induced low frequency jitter. In order to attenuate the higher frequency (greatet than 2.0 Hz) disturbances associated with reaction wheel static and dynamic imbalances, as well as bearing run-out, JWST will employ a two-stage passive vibration isolation system consisting of (1) 7.0 Hz reaction wheel isolators between each reaction wheel and the spacecraft bus, and (2) a 1.0 Hz tower isolator between the spacecraft bus and the Optical Telescope Element (OTE). In order to sense and measure the LOS, the FGS behaves much like an autonomous star tracker that has a very small field of view and uses the optics of the telescope. It performs the functions of acquisition, identification and tracking of stars in its 2.5 x 2.5 arcminute field of view (FOV), and provides the centroid and magnitude of the selected star for use in LOS control. However, since only a single star is being tracked

  7. James Webb Space Telescope Studies of Dark Energy (United States)

    Gardner, Jonathan P.; Stiavelli, Massimo; Mather, John C.


    time-variable source gives the angular diameter distance through measured time delays of multiple images. Finally, the growth of structure can also be constrained by measuring the mass of the largest galaxy clusters over cosmic time. HST has contributed to the study of dark energy through SN1a and gravitational lensing, as discussed above. HST has also helped to characterize galaxy clusters and the HST-measured constraints on the current Hubble constant H(sub 0) are relevant to the interpretation of dark energy measurements (Riess et al 2009a). HST has not been used to constrain BAO as the large number of galaxy redshifts required, of order 100 million, is poorly matched to HST's capabilities. As the successor to HST, the James Webb Space Telescope (JWST; Gardner et al 2006) will continue and extend HST's dark energy work in several ways.

  8. Obituary: James H. "Trex" Trexler, 1918-2005 (United States)

    Barker, Ed


    James H. "Trex" Trexler, Naval Center for Space Technology, a retired scientist and astronomer, with a 50-year career at NRL died of cancer on October 22, 2005, at the age of 87. Born in Missoula, Montana (May 18, 1918), he grew up in Dallas, Texas, and attended Southern Methodist University (SMU) Engineering School. He combined his interests in astronomy and radio communication and operated the observatory on the SMU campus. Mr. Trexler had a most interesting and rewarding career at NRL, which resulted in notable contributions in scientific and technical developments. While at SMU, he worked on a government-sponsored project on radio detection and tracking of meteors. This work resulted in a call from NRL in 1942 to join the Navy radio detection effort being mounted against the German submarine Wolf Packs that were harassing our North Atlantic convoys on the supply routes to our European Allies. The program proved highly successful causing the breakup of the German Pack operation, and resulted in the sinking and capturing of many U-boats. After World War II, Trex and H. O. Lorenzen brought the German Navy's very advanced Wullenweber Direction Finder back to NRL, and rebuilt it at the Washington Coast Guard Station, south of Alexandria. It served as the prototype for the Direction Finder at the heart of the Navy and Air Force intercept networks and later as the first tracker of the Soviet Sputnik. He received the Navy Meritorious Civilian Service Award for his efforts. In the late l940s, Trex built the radar intercept equipment for the Navy's P4M Airborne Cold War Ferret Program. This capability provided instantaneous frequency and direction of arrival against Soviet radars from high-altitude flights along the Soviet borders. His Radio Physics Branch developed a surface mobile intercept system deployed to the Near East for which the Navy made the first group cash incentive award. With the beginning of the space age, his branch examined the moon as a possible

  9. The radiation linked to uranium natural radioactivity enlightened by Abel Niepce long time before Henri Becquerel;Les rayonnements lies a la radioactivite naturelle de l'uranium mis en evidence par Abel Niepce bien avant Henri Becquerel

    Energy Technology Data Exchange (ETDEWEB)

    Fournier, J.; Niepce, J.C.


    Abel Niepce was rarely mentioned during the celebration of the centenary of the radioactivity discovery.This discovery, supposed due to chance alone, is entirely attributed to Henri Becquerel. But Abel Niepce who made the first observation of radiation from uranium with the impression of a photographic plate, but without giving it meaning. This is a slow process which in forty years, from an observation misunderstood by Abel Niepce to its interpretation by Frederick Soddy, through the experiments of Henri Becquerel and thanks to developments in other knowledge (electron, X-rays) has led to a scientific progress known under the term of radioactivity, name given by Marie Slodowska-Curie. (N.C.)

  10. The Forgotten Text of Nikolai Golovin: New Light on the Igor Tale

    Directory of Open Access Journals (Sweden)

    Robert Mann


    Full Text Available Mann argues that a rare text of the Skazanie o Mamaevom poboishche comes from an early, fifteenth-century redaction that scholars could never locate—a redaction that is the prototype for all the redactions that have been studied heretofore. He maintains that unique parallels between this redaction and the Slovo o polka Igoreve support the hypothesis that the Igor Tale was an oral epic song in a tradition that actually continued into the fourteenth and fifteenth centuries, when oral tales about the Kulikovo Battle (1380 were composed. He places the new parallels in the context of other evidence for oral composition in the Igor Tale.

  11. Une autre ville pour une autre vie. Henri Lefebvre et les situationnistes

    Directory of Open Access Journals (Sweden)

    Philippe Simay


    Full Text Available L’un des traits distinctifs du mouvement situationniste est de s’être constamment préoccupé de la question urbaine. Conçue comme l’espace de production de la société du spectacle mais aussi comme un terrain de lutte et d’expérimentation, la ville a représenté pour ce mouvement estudiantin, proche d’Henri Lefebvre, le lieu d’une réinvention radicale de la vie quotidienne. Cet article revient sur la critique situationniste de l’urbanisme de l’après-guerre ainsi que sur les pratiques auxquelles elle a donné lieu (détournement, dérive, cartes psychogéographiques, construction de situations éphémères. Celles-ci peuvent être regardées comme la première expression d’un « droit à la ville », tel que l’entendait Lefebvre. Reste à savoir si le groupe de Guy Debord souhaitait véritablement « changer la ville pour changer la vie » ou si la ville n’était que le théâtre d’une révolution à venir.One of the distinctive traits of the situationist movement is its constant preoccupation with the urban issue. For this student movement close to Henri Lefebvre, the city has been thought of as a choice generic location for the production of the Society of the Spectacle, but also as a test ground for struggle and experimentation – the place where a radical reinvention of daily life can occur. This paper goes back to the situationist critique of post-war urbanism, as well as the behaviors and practices it has given birth to (misappropriation, drifts in meaning, psychogeographic maps, the construct of short-lived situations. These can be seen as the first expression of a « right to the city », in the sense Lefebvre originally meant it have. However, it is still unknown whether Guy Debord's group really wished to « change city-life to change life itself », or if to them the city was merely a theater for the enactment of a revolution to come.

  12. King James II in Foreign Historiography: the Main Scientifi c Trends and Approaches .

    Directory of Open Access Journals (Sweden)

    Stankov Kirill


    Full Text Available The fate of the tragic figure of the British king James II Stuart is considered in the article. In this paper the author pays speсial attention to the history of investigation of the character and politics of this person by the British historians, as well as by the leading European and American specialists on the Early Modern Time. The estimates of James II are of vast variety in the British historiography but at the same time diff erent authors have some similar features in their attitude. Except the apologists the British historians on the whole criticized this king and explain that the majority of the problems connected with him are based on the religious factor that is not really right. On the other hand there are some differences in this negative approaches among various scientifi c schools of British historiography. The Whigs stated that James II tried to limit the personal rights of the Englishmen which was the main result of the English revolution of the middle of the 17th century. The Tories proved that the king neglected the gentry’s property rights and tried to transform the dualistic monarchy into absolutism. The Positivists thought that James II supported the Catholic Counterreformation and fought against the Enlightenment. The revisionists and postrevisionists tried to revalue the person of James II based on the true scientific foundations. A special view on James II’ policy is produced by Non-British authors: German, French and American historians.

  13. HB1204: Deep-Sea Corals and Benthic Habitats in Northeast Deepwater Canyons on NOAA Ship Henry Bigelow between 20120703 and 20120718 (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A multi-disciplinary team of scientists on the Henry Bigelow HB1204 mission surveyed and ground-truthed known or suspected deep-sea coral habitats associated with...

  14. Kuidas kommunikatsiooniga raha kaasata ehk sõna saab härra ühisrahastus / Henri Laupmaa ; intervjueerinud Dea Martinjonis

    Index Scriptorium Estoniae

    Laupmaa, Henri


    Intervjuu IT-ettevõtja, kodanikuühiskonna arendaja ning toetusplatvormi Hooandja ühe käivitaja Henri Laupmaaga Hooandja platvormi õnnestunud projektidest, uuest ühisrahastusplatvormist Fundwise, kommunikatsioonist ühisrahastusprojektide ellu viimisel

  15. [Crusading and chronicle writing on the medieval Baltic frontier: A companion to the chronicle of Henry of Livonia] / Radosław Biskup

    Index Scriptorium Estoniae

    Biskup, Radosław


    Arvustus: Crusading and chronicle writing on the medieval Baltic frontier : a companion to the chronicle of Henry of Livonia, eds. Marek Tamm, Linda Kaljundi, Carsten Selch Jensen. Farnham ; Burlington (Vt.) : Ashgate, c2011

  16. Polystyrene copolymer supported by substituted (1R,2R)-1,2-diphenylethane-1,2-diamine-copper(II) complexes: a recyclable catalyst for asymmetric Henry reactions

    Czech Academy of Sciences Publication Activity Database

    Androvič, L.; Drabina, P.; Panov, I.; Frumarová, Božena; Kalendová, A.; Sedlák, M.


    Roč. 25, č. 9 (2014), s. 775-780 ISSN 0957-4166 Institutional support: RVO:61389013 Keywords : cooper complexes * copolymers * asymmetric Henry reaction Subject RIV: CC - Organic Chemistry Impact factor: 2.155, year: 2014

  17. The National Shipbuilding Research Program. Proceedings of the REAPS Technical Symposium. Paper No. 21: Development of Effective Computer Capabilities by the J. J. Henry Company

    National Research Council Canada - National Science Library

    Fritz, W. B


    On April 2, 1980, the J. J. Henry Company, Inc signed an agreement with Cali & Associates to use the SPADES system of computer programs to enhance its preliminary contract and detail design service for its clients...

  18. Musicalidade e transmissao da voz: James, John e Lucia Joyce // Musicality and transmission of the voice: James, John and Lucia Joyce

    Directory of Open Access Journals (Sweden)

    Renata Mattos


    Full Text Available Este artigo tem como objetivo trabalhar a temática da voz, da música e do traço em James Joyce, seu pai John e sua filha Lucia com o intuito de pensar as diferentes saídas possíveis face à questão do sintoma da carência paterna, seja pela elevação ao sinthoma pela escrita de uma obra literária no caso de Joyce, seja pela tentativa de manejo da voz através da dança, no caso de Lucia. Propomos tomar a escrita de James Joyce naquilo que ela nos oferece para pensar a relação entre uma escrita possível da voz e a invocação ao Pai, detendo-nos na transmissão da voz efetuada nestas três gerações da família Joyce, no que cada um deles pôde, de maneiras singulares, criar face ao real. // The aim of this paper is to work the thematic of the voice, the music and the trait in James Joyce, his father John and his daughter Lucia in order to think about the question of the elevation of the symptom of the lack of the father through the writing of James Joyce in his literary work as well as though the relation of Lucia with the dance. Our proposal is to reflect about the writing of Joyce to think about the relation between a possible writing of the voice and the invocation to the Father, as well as the transmission of the voice made in these three generations of the Joyce family in what each one of them could, in different ways, create guided by the real.

  19. From James Hutton’s «Theory of the Earth» to James Lovelock’s «Gaia Hypothesis»

    Directory of Open Access Journals (Sweden)

    García Cruz, Cándido Manuel


    Full Text Available In order to understand to what extent James Hutton (1726-1797 can in fact be considered as one of the first forerunners of the Gaia Hypothesis, his Theory of the Earth is analysed into context
    of the three basic traditions of science: organismic, magical and mechanistic. In the some authors’ opinion, Hutton should have written in his theory the Earth was a superorganism and its proper
    study should be by physiology. These supposed assertions are merely a misinterpretation of the Huttonian philosophy, since were never held by this author. Hutton has nevertheless an holistic view which is closer to the Alfred N. Whitehead's organic mechanicism than the James Lovelock's
    Gaia Hypothesis, being therefore a clear forerunner of Ludwig von Bertalanffy and his System
    General Theory.

    Para comprender en qué medida James Hutton (1726-1797 puede ser considerado en realidad como uno de los primeros precursores de la Hipótesis Gaia, se analiza su Theory of the Earth en el contexto de las tres tradiciones básicas de la ciencia: la organísmica, la mágica y la mecanicista. Para algunos autores, Hutton habría sugerido en su teoría que la tierra era un superorganismo y que la forma más correcta para estudiarla era la fisiología. Estas supuestas afirmaciones son simplemente una interpretación errónea del pensamiento huttoniano, puesto que este autor nunca las hizo. Sin embargo, Hutton posee de hecho una visión holística que está más próxima al mecanicismo orgánico de Alfred N. Whitehead que a la Hipótesis Gaia de James Lovelock, siendo por tanto un claro precursor de Ludwig von Bertalanffy y su Teoría General de Sistemas.

  20. A unified description of adsorption on real surfaces from the Henry Range to the formation of the liquid layer

    Energy Technology Data Exchange (ETDEWEB)

    Cerofolini, G F


    A unified description of adsorption on real surfaces from the Henry Range to the formation of the liquid layer was developed on the basis of the BET theory and the assumption that sites on real surfaces are not energetically homogeneous. The model describes the successive Henry, Dubinin-Radushkevich, Freundlich, and multilayer BET behavior of the adsorbed phase as the pressure increases. An analysis of isotherms over the whole coverage range showed that the heterogeneous surface character decreases with increasing number of adsorbed layers; that adsorption into the first and higher layers may be competitive, which produces a new isotherm resembling a mixed type II and III isotherm as proposed by Cerofolini and coworkers.

  1. The urban short story cycle before Joyce: James Stephens’ Here are Ladies


    Brouckmans, Debbie


    Published ten years after George Moore’s The Untilled Field (1903) and one year before James Joyce’s Dubliners (1914), James Stephens’ Here are Ladies (1913) consists of short stories, poems and monologues. The work is not often discussed, presumably because it is rather difficult to define. It is usually classified as a collection of short stories, but this neglects the poems and monologues and fails to do justice to the thematic and formal links between the texts. Therefore, I would like to...

  2. James Webb Space Telescope Optical Telescope Element Mirror Development History and Results (United States)

    Feinber, Lee D.; Clampin, Mark; Keski-Kuha, Ritva; Atkinson, Charlie; Texter, Scott; Bergeland, Mark; Gallagher, Benjamin B.


    In a little under a decade, the James Webb Space Telescope (JWST) program has designed, manufactured, assembled and tested 21 flight beryllium mirrors for the James Webb Space Telescope Optical Telescope Element. This paper will summarize the mirror development history starting with the selection of beryllium as the mirror material and ending with the final test results. It will provide an overview of the technological roadmap and schedules and the key challenges that were overcome. It will also provide a summary or the key tests that were performed and the results of these tests.

  3. James Bay Mercury Committee report of activities. Rapport d'activites du Comite de la Baie James sur le mercure

    Energy Technology Data Exchange (ETDEWEB)


    The James Bay Mercury Committee has the mandate to oversee the implementation of the research, monitoring, and remediation programs related to the mercury pollution problem associated with hydroelectric developments in the James Bay region of Quebec. A summary of activities for 1990-91 is presented. Monitoring programs conducted during the year included studies of fish in the western part of the LaGrande complex, in which a decrease in Hg levels first noted in 1990 persisted; and a hair sampling and analysis program conducted on high-risk groups in the James Bay Cree population, which noted a continuing downward trend in Hg levels although this trend was not statistically significant. Research programs included a study of the influence of environmental factors on the release of Hg from vegetation and soil flooded by hydroelectric reservoirs. Mercury research in 1990 allowed confirmation of the fact that a higher Hg uptake in certain fish downstream from the LaGrande 2 station was related to a change in their feeding habits. Other studies were conducted on the effects of methylmercury exposure on health, sociocultural and economic aspects, and mitigative measures. Total expenditures for the year were just over $2 million. 8 refs., 3 figs., 2 tabs.

  4. Meet the HENRYs: A hybrid focus group study of conspicuous luxury consumption in the social media context


    Kennedy, G.; Bolat, Elvira


    Social media has created different dimension of consumers for luxury products, specifically the aspirational consumer who wishes to own a product, but for economic reasons cannot. In other words aspirational consumers use luxury brands to create value for themselves using social media to conspicuously consume without purchase. Aspirational consumers are mostly found among HENRYs (high earners, not rich yet). Studies around conspicuous consumption of luxury products as a result of digital tech...

  5. [Charles-Henri Fialon (1846-1933). Creator of the historical museum of the faculty of pharmacy of Paris]. (United States)

    Bzoura, Elie; Flahaut, Jean


    Charles-Henri Fialon stopped his pharmaceutical activities in 1892 and he devoted his time to artistic and historic works. He achieved an important collection of pharmaceutical pots and objects which he gave to the school of Pharmacy of Paris. These gifts were collected in a room named "Musée Fialon ". This museum was enlarged twice and presently is in the "Guillaume Valette" gallery. His content is described in this paper.

  6. Role of postoperative radiotherapy in the treatment of Merkel tumours: experience at the Henri Mondor Hospital on 21 cases

    International Nuclear Information System (INIS)

    Calitchi, E.; Pan, Q.; Diana, C.; Belkacemi, Y.; Lagrange, J.L.


    As Merkel tumour treatment modalities are still a matter of discussion, the authors report the experience gained on 21 patients in the radiotherapy department of the Henri Mondor Hospital between 1990 and 2005. The treatment always comprised a surgical exeresis followed by radiotherapy. The authors analyse the obtained results which confirm the interest of postoperative radiotherapy. The detailed analysis of modalities (radiation type, total dose, irradiation volume) allows an optimal irradiation scheme to be proposed. Short communication

  7. Review of James L. Baughman, Jennifer Ratner-Rosenhagen, and James P. Danky, eds, Protest on the Page: Essays on Print and the Culture of Dissent since 1865 (2015

    Directory of Open Access Journals (Sweden)

    Maria Zirra


    Full Text Available James L. Baughman, Jennifer Ratner-Rosenhagen, and James P. Danky, eds, Protest on the Page: Essays on Print and the Culture of Dissent since 1865 (Madison: University of Wisconsin Press, 2015. xv + 259 pp. ISBN 978-0-299-30284-9.

  8. A Tale of Two Authors: Valenzuela and Borges

    Directory of Open Access Journals (Sweden)

    Sharon Magnarelli


    Full Text Available Although Luisa Valenzuela and Borges were friends for many years, it is only recently that we find traces of that friendship in her narrative. "La calesita" and "El otro libro," published in 1998 and 1999 respectively, evoke many of the elements we find in Borges's narrative. The latter story, which is the main focus of this study, employs nearly all the narrative elements we have come to associate with the Argentine master. Nonetheless, a single sign is changed as Borges's male characters are replaced by females in Valenzuela's work. The end result is a tribute to Borges but one that challenges us to perceive the world differently and to seek the "god behind God [that] begins the tale/game" of the master narratives and to whom Borges alludes in his poem, "Ajedrez."

  9. Genome Engineering with TALE and CRISPR Systems in Neuroscience. (United States)

    Lee, Han B; Sundberg, Brynn N; Sigafoos, Ashley N; Clark, Karl J


    Recent advancement in genome engineering technology is changing the landscape of biological research and providing neuroscientists with an opportunity to develop new methodologies to ask critical research questions. This advancement is highlighted by the increased use of programmable DNA-binding agents (PDBAs) such as transcription activator-like effector (TALE) and RNA-guided clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR associated (Cas) systems. These PDBAs fused or co-expressed with various effector domains allow precise modification of genomic sequences and gene expression levels. These technologies mirror and extend beyond classic gene targeting methods contributing to the development of novel tools for basic and clinical neuroscience. In this Review, we discuss the recent development in genome engineering and potential applications of this technology in the field of neuroscience.

  10. Genome Engineering with TALE and CRISPR Systems in Neuroscience (United States)

    Lee, Han B.; Sundberg, Brynn N.; Sigafoos, Ashley N.; Clark, Karl J.


    Recent advancement in genome engineering technology is changing the landscape of biological research and providing neuroscientists with an opportunity to develop new methodologies to ask critical research questions. This advancement is highlighted by the increased use of programmable DNA-binding agents (PDBAs) such as transcription activator-like effector (TALE) and RNA-guided clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR associated (Cas) systems. These PDBAs fused or co-expressed with various effector domains allow precise modification of genomic sequences and gene expression levels. These technologies mirror and extend beyond classic gene targeting methods contributing to the development of novel tools for basic and clinical neuroscience. In this Review, we discuss the recent development in genome engineering and potential applications of this technology in the field of neuroscience. PMID:27092173

  11. Duss Fairy Tales: some data from a new evaluation form. (United States)

    Mazzeschi, C; Lis, A; Calvo, V; Vallone, V; Superchi, E


    The purpose of this paper is to extend the research on the Duss Fairy Tales in an Italian sample. Attention has been paid, in particular, to the study of some variables identified in a newly devised schedule. The protocols were scored for four indexes: (1) the main hero of the stories, (2) number and types of characters, (3) number of emotions expressed, and (4) number of heroes' and characters' actions and behaviors. Subjects were 70 children aged 3.5 to 10.5 yr. enrolled in kindergartens and elementary schools in Italy. The relationships of scores with age and sex were also investigated. There was an increase across three age groups in the richness of stories in terms of emotions and characters' identification.

  12. Dissection of TALE-dependent gene activation reveals that they induce transcription cooperatively and in both orientations. (United States)

    Streubel, Jana; Baum, Heidi; Grau, Jan; Stuttman, Johannes; Boch, Jens


    Plant-pathogenic Xanthomonas bacteria inject transcription activator-like effector proteins (TALEs) into host cells to specifically induce transcription of plant genes and enhance susceptibility. Although the DNA-binding mode is well-understood it is still ambiguous how TALEs initiate transcription and whether additional promoter elements are needed to support this. To systematically dissect prerequisites for transcriptional initiation the activity of one TALE was compared on different synthetic Bs4 promoter fragments. In addition, a large collection of artificial TALEs spanning the OsSWEET14 promoter was compared. We show that the presence of a TALE alone is not sufficient to initiate transcription suggesting the requirement of additional supporting promoter elements. At the OsSWEET14 promoter TALEs can initiate transcription from various positions, in a synergistic manner of multiple TALEs binding in parallel to the promoter, and even by binding in reverse orientation. TALEs are known to shift the transcriptional start site, but our data show that this shift depends on the individual position of a TALE within a promoter context. Our results implicate that TALEs function like classical enhancer-binding proteins and initiate transcription in both orientations which has consequences for in planta target gene prediction and design of artificial activators.

  13. A pioneer of Australian paediatrics: Dr Henry Edward Brown (1858-1931). (United States)

    Isles, Alan F; Roper, Peter; Pearn, John H


    The emergence of paediatrics as a specialty in Australian medicine dates from the last two decades of the 19th century. Among the pioneers of pre-Federation paediatrics, we include Dr Henry Edward Brown (1858-1931), an Irish-born physician and surgeon who became the first paediatrician to practise in the northern half of the Australian continent. In 1885, he was appointed as the medical superintendent of the Rockhampton Children's Hospital, itself a pioneer institution in the care of sick and injured children. Dr H.E. Brown also served as medical officer of health concurrently in three Queensland shires. He was a leader in the literary and sporting life of the busy port town of Rockhampton and a scholar and significant philanthropist in the domain of French literature. His life was and remains an exemplar of a class of pre-Federation paediatricians who established the ethos of clinical and societal service, which remains as a core feature of the speciality discipline of paediatrics in the 21st century. © 2014 The Authors. Journal of Paediatrics and Child Health © 2014 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

  14. El urbanismo contra lo urbano. La ciudad y la vida urbana en Henri Lefebvre

    Directory of Open Access Journals (Sweden)

    Manuel Delgado Ruiz


    Full Text Available Henri Lefebvre coloca en el eje de su teoría sobre la vida urbana la oposición entre el espacio vivido por quienes lo usan o sueñan y el espacio abstracto que creen organizar los tecnócratas de la ciudad, que raramente reconocen hasta qué punto su “creatividad” está sometida a intereses privados o institucionales. Tras ese espacio hipotético sobre el que urbanistas y arquitectos trabajan no hay otra cosa que mera ideología, es decir, fantasma que recubre y disfraza las relaciones sociales reales de producción. Frente -o de espaldas- a ese orden espacial meramente teórico de los “especialistas”, lo que las ciudades conocen es la actividad constante o inminente de lo urbano, entendido como apoteosis y exacerbación de lo social, dinamismo siempre activado de acontecimientos y quehaceres sobre el que los “expertos” aplican planes y proyectos, pero del que no saben en realidad nada, acaso por lo cual pugnan por anularlo.

  15. Derivation of the MMPI-2-RF Henry-Heilbronner Index-r (HHI-r) scale. (United States)

    Henry, George K; Heilbronner, Robert L; Algina, James; Kaya, Yasemin


    The 15-item Henry-Heilbronner Index (HHI) was published in 2006 as an MMPI-2 embedded measure of psychological response validity. When the MMPI-2 was revised in 2008 only 11 of the 15 original HHI items were retained on the MMPI-2-RF, prohibiting use of the HHI as an embedded validity indicator on the MMPI-2-RF. Using the original HHI sample an 11-item version of the HHI, the HHI-r, was evaluated for use as an embedded measure of psychological response validity for the MMPI-2-RF. The 11-item HHI-r was very similar to the HHI in classification accuracy. An HHI-r cutoff score of ≥7 was associated with a classification accuracy rate of 84.0%, good sensitivity (68.9%), and high specificity (93.2%) in identifying symptom exaggeration in personal injury and disability litigants versus non-litigating head-injured patients. These preliminary results suggest the HHI-r functions in a manner similar to the original HHI as a measure of psychological response validity, and may be used by psychologists and neuropsychologists as an MMPI-2-RF embedded validity indicator.

  16. Henry's Law vaporization studies and thermodynamics of einsteinium-253 metal dissolved in ytterbium

    International Nuclear Information System (INIS)

    Kleinschmidt, P.D.; Ward, J.W.; Matlack, G.M.; Haire, R.G.


    The cohesive energy of metallic einsteinium determines whether einsteinium is a trivalent or divalent metal. The enthalpy of sublimation, a measure of the cohesive energy, is calculated from the partial pressures of einsteinium over an alloy. The partial pressure of 253 Es has been measured over the range 470--870 K, using combined target and mass spectrometric Knudsen effusion techniques. An alloy was prepared with einsteinium dissolved in a ytterbium solvent to produce a very dilute solution. Partial pressure measurements on the alloy were amenable to the experimental technique and a data analysis using a Henry's law treatment of the data. Vapor pressure data are combined with an estimated crystal entropy S 0 298 and ΔC 0 /sub p/ for ytterbium, to produce enthalpy, entropy, and free energy functions from 298 to 1300 K. The vapor pressure of einsteinium in a dilute einsteinium--ytterbium alloy is described by the equation log P(atm) = -(6815 +- 216)/T+2.576 +- 0.337, from which we calculate for the enthalpy of sublimation of pure einsteinium ΔH 0 298 (second law) = 31.76 kcal/mol. The value of the enthalpy of sublimation is consistent with the conclusion that Es is a divalent metal

  17. Oestrogen and progesterone receptor assays in breast tumours. The Prince Henry's Hospital experience, 1983-1990. (United States)

    Pearce, P T; Myles, K M; Funder, J W


    To present and analyse the results of eight years of experience (1983-1990) in breast tumour receptor analysis. All female primary breast tumour samples received (4683) were analysed for seasonal variation, patient age, relative risk index, oestrogen receptor (ER) and progesterone receptor (PR) status, ER and PR status as a function of age, ER and PR levels as a function of age, and ER and PR levels as a function of month of analysis. The assays were done at the Medical Research Centre, Prince Henry's Hospital, Melbourne, as a non-profit service to surgeons, oncologists and pathologists. The numbers of samples referred for assay increased progressively each year, from 473 in 1983 to 1097 in 1990, but the receptor status (ER +/-, PR +/-) appeared not to vary from year to year. ER+PR+ tumours were the most common in all age groups, steadily increasing from between 50% and 60% in premenopausal women to 70% or more in those aged over 80. In postmenopausal women, levels of ER in ER+ tumours were three times those in premenopausal women; PR levels in PR+ tumours, however, were bimodal, with higher levels in the age groups 35-49 and 70-89 years than in women aged 50-69 years. No significant seasonal variation was seen, and the overall patterns of receptor status are similar to those seen in Northern hemisphere studies.

  18. [Henri-Léonard Bertin and the development of agriculture in the Age of Enlightenment]. (United States)

    Pédro, Georges


    This meeting of the Committee on the History of Science and Epistemology takes place as we celebrate the 250th anniversary of the creation of the world's first veterinary schools, a major event among all those that, in the wake of the Physiocrat movement initiated by Quesnay and DuPont de Nemours, shaped the modernisation of agriculture in France during the 18th century. Henri-Léonard Bertin (1720-1792) was the impetus to the restructuring process. He was well aware that farming should not remain an activity that solely provides a livelihood for the population, but that it needed to be modernised, i.e. it should produce more, and better. His view was that agriculture could become a great source of riches for France and therefore, a true economic and even political force. He used the various official positions he occupied during that period (Intendant of Lyon (1754-1757), Controller General of Finances (1759-1763), Minister-Secretary of State for Agriculture (1763-1780) to initiate a number of reforms that brought about the modernisation of the kingdom's agricultural world. Copyright © 2012 Académie des sciences. Published by Elsevier SAS. All rights reserved.

  19. Reformation or Revolution? Herman Bavinck and Henri de Lubac on Nature and Grace

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    Parker Gregory W.


    Full Text Available Henri de Lubac’s treatment of the relationship between nature and grace will be critiqued by Herman Bavinck’s ‘grace restores nature’ theme. In two significant addresses, Bavinck critiqued a Roman Catholic approach to nature and grace. De Lubac’s influence upon Roman Catholic thinking addressing nature and grace occurred post-Bavinck and has altered Catholic thinking on the subject. Neo-Calvinist scholar, Wolter Huttinga admits that Bavinck and de Lubac offer similar critiques of Roman Catholicism (Huttinga 2014. The question remains then, do Bavinck’s critiques still hold? I propose that Bavinck’s account of grace restores nature still makes valid critiques of a post-Vatican II construction of nature and grace. The paper is broken into three sections: (1 an exploration of de Lubac’s nature and grace theme, (2 the framework of Bavinck’s ‘grace restores nature’ theme, and (3 a Bavinckian critique of de Lubac’s nature and grace theme.

  20. Henri Bergson y George Bernard Shaw: hábito, vida, muerte

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    Álvaro Cortina Urdampilleta


    Full Text Available Este artículo indaga en algunos aspectos de la antropología filosófica expuesta en la obra del francés Henri Bergson. Para ello, nos serviremos de la confrontación de su doctrina original con la de un bergsoniano sui generis, el intelectual y dramaturgo irlandés George Bernard Shaw. El Prefacio. A medio siglo infiel, de Shaw, incluido en su obra más ambiciosa, Vuelta a Matusalén. Un Pentateuco Metabiológico, de 1921, será el texto base con el que haremos dialogar a Bergson con este periférico bergsonismo. Tomaremos como hilo conductor la teoría sobre el hábito, en el contexto de la metafísica de la evolución de los seres orgánicos, y lo llevaremos hasta el concepto límite, que parece conciliar ambas posturas: la idea de muerte superable. Ni en Bergson ni en Shaw los hábitos (la Cultura forman parte integral de la esencia del hombre, y la muerte (cuestión en la que Bergson es mucho más elusivo juega en ellos un rol anfibio, entre Cultura y Naturaleza.