Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma

DEFF Research Database (Denmark)

Drent, Esther; Groen, Richard W. J.; Noort, Willy A. Noort

2016-01-01

Adoptive transfer of chimeric antigen receptor-transduced T cells is a promising strategy for cancer immunotherapy. The CD38 molecule, with its high expression on multiple myeloma cells, appears a suitable target for antibody therapy. Prompted by this, we used three different CD38 antibody...... sequences to generate second-generation retroviral CD38- chimeric antigen receptor constructs with which we transduced T cells from healthy donors and multiple myeloma patients. We then evaluated the preclinical efficacy and safety of the transduced T cells. Irrespective of the donor and antibody sequence......, CD38-chimeric antigen receptor-transduced T cells proliferated, produced inflammatory cytokines and effectively lysed malignant cell lines and primary malignant cells from patients with acute myeloid leukemia and multi-drug resistant multiple myeloma in a cell-dose, and CD38-dependent manner, despite...

Spontaneous CD8 T cell responses against the melanocyte differentiation antigen RAB38/NY-MEL-1 in melanoma patients.

Science.gov (United States)

Walton, Senta M; Gerlinger, Marco; de la Rosa, Olga; Nuber, Natko; Knights, Ashley; Gati, Asma; Laumer, Monika; Strauss, Laura; Exner, Carolin; Schäfer, Niklaus; Urosevic, Mirjana; Dummer, Reinhard; Tiercy, Jean-Marie; Mackensen, Andreas; Jaeger, Elke; Lévy, Frédéric; Knuth, Alexander; Jäger, Dirk; Zippelius, Alfred

2006-12-01

The melanocyte differentiation Ag RAB38/NY-MEL-1 was identified by serological expression cloning (SEREX) and is expressed in the vast majority of melanoma lesions. The immunogenicity of RAB38/NY-MEL-1 has been corroborated previously by the frequent occurrence of specific Ab responses in melanoma patients. To elucidate potential CD8 T cell responses, we applied in vitro sensitization with overlapping peptides spanning the RAB38/NY-MEL-1 protein sequence and the reverse immunology approach. The identified peptide RAB38/NY-MEL-1(50-58) exhibited a marked response in ELISPOT assays after in vitro sensitization of CD8 T cells from HLA-A *0201(+) melanoma patients. In vitro digestion assays using purified proteasomes provided evidence of natural processing of RAB38/NY-MEL-1(50-58) peptide. Accordingly, monoclonal RAB38/NY-MEL-1(50-58)-specific T cell populations were capable of specifically recognizing HLA-A2(+) melanoma cell lines expressing RAB38/NY-MEL-1. Applying fluorescent HLA-A2/RAB38/NY-MEL-1(50-58) multimeric constructs, we were able to document a spontaneously developed memory/effector CD8 T cell response against this peptide in a melanoma patient. To elucidate the Ag-processing pathway, we demonstrate that RAB38/NY-MEL-1(50-58) is produced efficiently by the standard proteasome and the immunoproteasome. In addition to the identification of a RAB38/NY-MEL-1-derived immunogenic CD8 T cell epitope, this study is instrumental for both the onset and monitoring of future RAB38/NY-MEL-1-based vaccination trials.

Preparation of high specific activity labelled triiodothyronine (T3) for radioimmunoassay

International Nuclear Information System (INIS)

Pillai, M.R.A.; Nagvekar, U.H.; Desai, C.N.; Mani, R.S.

1981-01-01

A method standardized for the preparation of high specific activity labelled triiodothyronine (T 3 ) is discussed. Iodine-125 labelled T 3 with a specific activity of 3 mCi μg was prepared by iodinating 3,5-diiodothyronine (T 2 ) and purifying it over Sephadex G-25 gel. Radochemical purity and stability evaluations were done by paper chromatography. Specific activity of the labelled T 3 prepared was estimated by the self-displacement method. The use of this high specific activity labelled T 3 in radioimmunoassay increased the sensitivity considerably. The advantage of this procedure is that the specific activity of labelled T 3 formed is independent of reaction yield and labelled T 3 yield. (author)

Conversion of the dual training aircraft (DC into single control advanced training aircraft (SC. Part I

Directory of Open Access Journals (Sweden)

Ioan ŞTEFĂNESCU

2011-03-01

Full Text Available Converting the DC school jet aircraft into SC advanced training aircraft - and use them forthe combat training of military pilots from the operational units, has become a necessity due to thebudget cuts for Air Force, with direct implications on reducing the number of hours of flight assignedto operating personnel for preparing and training.The purpose of adopting such a program is to reduce the number of flight hours allocated annuallyfor preparing and training in advanced stages of instruction, for every pilot, by more intensive use ofthis type of aircraft, which has the advantage of lower flight hour costs as compared to a supersoniccombat plane.

Indexing, screening, coding and cataloging of earth resources aircraft mission data

Science.gov (United States)

1977-01-01

Tasks completed are as follows: (1) preparation of large Area Crop Inventory experiment for data base entry;(2) preparation of Earth Observations Aircraft Flight summary reports for publication; (3) updating of the aircraft mission index coverage map and Ames aircraft flight map; (4) Prepared of Earth Observation Helicopter Flight reports for publication; and (5) indexing of LANDSAT imagery. (6) formulation of phase 3 biowindows 1, 2, 3, and 4 listings by country, footprint, and acqusition dates; (7) preparation of flight summary reports; and (8) preparation of an Alaska state index coverage map.

Daratumumab depletes CD38sup>+> immune-regulatory cells, promotes T-cell expansion, and skews T-cell repertoire in multiple myeloma

DEFF Research Database (Denmark)

Krejcik, Jakub; Casneuf, Tineke; Nijhof, Inger S

2016-01-01

target non-plasma cells that express CD38, which prompted evaluation of daratumumab's effects on CD38-positive immune subpopulations. Peripheral blood (PB) and bone marrow (BM) from patients with relapsed/refractory myeloma from two daratumumab monotherapy studies were analyzed before and during therapy......Daratumumab targets CD38-expressing myeloma cells through a variety of immune-mediated mechanisms (complement-dependent cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and antibody-dependent cellular phagocytosis) and direct apoptosis with cross-linking. These mechanisms may also...... and at relapse. Regulatory B cells (Bregs) and myeloid-derived suppressor cells (MDSCs), previously shown to express CD38, were evaluated for immunosuppressive activity and daratumumab sensitivity in the myeloma setting. A novel subpopulation of regulatory T cells (Tregs) expressing CD38 was identified...

Reduced Plasmodium Parasite Burden Associates with CD38+ CD4+ T Cells Displaying Cytolytic Potential and Impaired IFN-γ Production

Science.gov (United States)

Burel, Julie G.; Apte, Simon H.; Groves, Penny L.; Klein, Kerenaftali; McCarthy, James S.; Doolan, Denise L.

2016-01-01

Using a unique resource of samples from a controlled human malaria infection (CHMI) study, we identified a novel population of CD4+ T cells whose frequency in the peripheral blood was inversely correlated with parasite burden following P. falciparum infection. These CD4+ T cells expressed the multifunctional ectoenzyme CD38 and had unique features that distinguished them from other CD4+ T cells. Specifically, their phenotype was associated with proliferation, activation and cytotoxic potential as well as significantly impaired production of IFN-γ and other cytokines and reduced basal levels of activated STAT1. A CD38+ CD4+ T cell population with similar features was identified in healthy uninfected individuals, at lower frequency. CD38+ CD4+ T cells could be generated in vitro from CD38- CD4+ T cells after antigenic or mitogenic stimulation. This is the first report of a population of CD38+ CD4+ T cells with a cytotoxic phenotype and markedly impaired IFN-γ capacity in humans. The expansion of this CD38+ CD4+ T population following infection and its significant association with reduced blood-stage parasite burden is consistent with an important functional role for these cells in protective immunity to malaria in humans. Their ubiquitous presence in humans suggests that they may have a broad role in host-pathogen defense. Trial Registration ClinicalTrials.gov clinical trial numbers ACTRN12612000814875, ACTRN12613000565741 and ACTRN12613001040752 PMID:27662621

The Aircraft Industry

National Research Council Canada - National Science Library

Fitzgerald, Tim; Baiche, Noureddine; Brewer, Mike; Collins, Al; Knapp, Kathy; Kott, Marilyn; McGill, Duncan; Mensah, Dunstan; Neighbors, Mark; Reardon, Dee

2005-01-01

.... As the airline companies prepare to buy new Boeing and Airbus passenger jets, they remain under intense pressure to cut costs in order to remain profitable, forcing aircraft and engine manufacturers...

77 FR 33083 - Airworthiness Directives; WACO Classic Aircraft Corporation Airplanes

Science.gov (United States)

2012-06-05

... Airworthiness Directives; WACO Classic Aircraft Corporation Airplanes AGENCY: Federal Aviation Administration... directive (AD) for certain WACO Classic Aircraft Corporation Models 2T-1A, 2T-1A-1, and 2T-1A-2 airplanes... information identified in this AD, contact WACO Classic Aircraft Corporation; 15955 South Airport Rd., Battle...

Preparation and Characterization of SN-38-Encapsulated Phytantriol Cubosomes Containing α-Monoglyceride Additives.

Science.gov (United States)

Ali, Md Ashraf; Noguchi, Shuji; Iwao, Yasunori; Oka, Toshihiko; Itai, Shigeru

2016-01-01

SN-38 is a potent active metabolite of irinotecan that has been considered as an anticancer candidate. However, the clinical development of this compound has been hampered by its poor aqueous solubility and chemical instability. In this study, we developed SN-38-encapsulated cubosomes to resolve these problems. Six α-monoglyceride additives, comprising monocaprylin, monocaprin, monolaurin, monomyristin, monopalmitin, and monostearin, were used to prepare phytantriol (PHYT) cubosomes by probe sonication. The mean particle size, polydispersity index, and zeta potential values of these systems were around 190-230 nm, 0.19-0.25 and -17 to -22 mV, respectively. Small-angle X-ray scattering analyses confirmed that the SN-38-encapsulated cubosomes existed in the Pn̄3m space group both with and without the additives. The monoglyceride additives led to around a two-fold increase in the solubility of SN-38 compared with the PHYT cubosome. The drug entrapment efficiency of PHYT cubosomes with additives was greater than 97%. The results of a stability study at 25°C showed no dramatic changes in the particle size or polydispersity index characteristics, with at least 85% of the SN-38 existing in its active lactone form after 10 d, demonstrating the high stability of the cubosome nanoparticles. Furthermore, approximately 55% of SN-38 was slowly released from the cubosomes with additives over 96 h in vitro under physiological conditions. Taken together, these results show that the SN-38-encapsulated PHYT cubosome particles are promising drug carriers that should be considered for further in vivo experiments, including drug delivery to tumor cells using the enhanced permeability and retention effect.

Increased numbers of CD38 molecules on bright CD8+ T lymphocytes in infectious mononucleosis caused by Epstein–Barr virus infection

Science.gov (United States)

ŽIDOVEC LEPEJ, S; VINCE, A; ÐAKOVIĆ RODE, O; REMENAR, A; JEREN, T

2003-01-01

The aim of this study was to quantify the expression of CD38 on CD8+ T lymphocytes of patients with infectious mononucleosis (IM) caused by Epstein–Barr virus (EBV) and cytomegalovirus (CMV). CD38 quantification technique chosen for this study was based on the enumeration of CD38 antibody binding sites in comparison to the quantification standards rather than determining relative fluorescence, which is difficult to standardize. The study enrolled 19 patients with typical clinical and laboratory parameters compatible with EBV-induced IM as well as 10 patients with atypical clinical presentation of this disease. Furthermore, CD38 expression was analysed in a group of 13 patients with IM caused by CMV infection. CD38 quantification was performed within 6 days of the presentation of symptoms. All three groups of IM patients showed a statistically significant increase in the number of anti-CD38 antibody binding sites (which correspond to the number of CD38 molecules) on bright CD8+ T lymphocytes compared to healthy controls. The numbers of CD38 molecules expressed on CD8+ T lymphocytes did not differ significantly between IM patients with typical and atypical clinical presentation of the disease. Patients with CMV-induced IM had significantly lower numbers of CD38 molecules expressed on CD8+ T lymphocytes. Therefore, we conclude that CD38 quantification could be helpful in differential diagnostics of IM cases with atypical clinical presentation. PMID:12930365

Aircraft Carriers

DEFF Research Database (Denmark)

Nødskov, Kim; Kværnø, Ole

as their purchases of aircraft carrier systems, makes it more than likely that the country is preparing such an acquisition. China has territorial disputes in the South China Sea over the Spratly Islands and is also worried about the security of its sea lines of communications, by which China transports the majority......, submarines, aircraft and helicopters, is not likely to be fully operational and war-capable until 2020, given the fact that China is starting from a clean sheet of paper. The United States of America (USA), the United Kingdom (UK), Russia and India are currently building or have made decisions to build new...

77 FR 31169 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

Science.gov (United States)

2012-05-25

... Airworthiness Directives; Piper Aircraft, Inc. Airplanes AGENCY: Federal Aviation Administration (FAA), DOT... Piper Aircraft, Inc. (type certificate previously held by The New Piper Aircraft Inc.) Models PA-31T and..., contact Piper Aircraft, Inc., 926 Piper Drive, Vero Beach, Florida 32960; telephone: (772) 567-4361...

Environmental Aspects of Aircraft and Airfield Deicing - An Air Force Perspective

Science.gov (United States)

2010-11-01

e l l e n c e COD of Aircraft Deicers ADF Kg O2/Kg compd Ethylene glycol 1.14 T Propylene glycol 1.47 T Isopropyl alcohol 2.11 T Neopentyl glycol ...showed that commercial airports use about 25 million gallons of Aircraft Deicing Fluid (ADF) annually, of which 22.1 M (88%) is Propylene Glycol (PG...S e r v i c e - E x c e l l e n c e AF Aircraft Deicing Overview 70% (107) of bases reported using aircraft deicers Propylene Glycol (PG), AMS 1424

Preparation and in vitro characterization of SN-38-loaded, self-forming polymeric depots as an injectable drug delivery system.

Science.gov (United States)

Manaspon, Chawan; Hongeng, Suradej; Boongird, Atthaporn; Nasongkla, Norased

2012-10-01

This work describes the preparation and characterization of anticancer-loaded injectable polymeric depots that consisted of D,L-lactide (LA), ε-caprolactone (CL), and poly(ethylene glycol) (PEG) or [poly(ε-caprolactone)-random-poly(D,L-lactide)]-block-poly(ethylene glycol)-block-[poly(ε-caprolactone)-random-poly(D,L-lactide)] (PLEC) copolymers for malignant gliomas treatment. PLECs were polymerized with different percentages of LA to deliver 7-ethyl-10-hydroxycamptothecin (SN-38), a highly potent anticancer drug. SN-38-loaded depots could form directly in phosphate buffer saline with more than 98% encapsulation efficiency. The release rate of SN-38 from depots was found to depend on the amount of LA in PLECs, loading content of SN-38 in the depots, and depot weight. Encapsulation of SN-38 inside depots could enhance the stability of SN-38 where all of SN-38 released after 60 days was in an active form. Depots without SN-38 were evaluated as noncytotoxic against U-87MG, whereas SN-38-loaded depots showed cytotoxic effect as a function of concentration. Copyright © 2012 Wiley Periodicals, Inc.

Observations of the dynamics of ionic potassium-38 in brain

International Nuclear Information System (INIS)

Duncan, C.C.; Lambrecht, R.M.; Bennett, G.W.; Rescigno, A.; Ment, L.R.

1984-01-01

Short time course potassium dynamics in brain were investigated in the cat. 38 K (T1/2 . 7.6m) was prepared on the BNL 60'' cyclotron by the 40 Ar(p, 3n) 38 K reaction. Positron decay in brain was measured by the limited angle of view positron camera (LAPC). Radioactivity corrected for physical decay following intravenous bolus injection of 38 K showed an initial peak followed by a washout phase with a subsequent monotonic increase. The slope of the washout phase was linearly related to PaCO2 and the subsequent monotonic increase paralleled the arterial concentration of the tracer. No significant changes in 38 K radioactivity were determined following coma producing levels of phenobarbital or seizure producing doses of potassium penicillin as compared to control

THE KINETICS OF CONTAMINANTS ACCUMULATION IN THE JET FUEL DURING THE TECHNOLOGICAL PROCESS OF ITS PREPARATION FOR AIRCRAFT REFUELING

Directory of Open Access Journals (Sweden)

A. A. Brailko

2017-01-01

Full Text Available Much attention is payed to the tasks for ensuring domestic and international aircraft safety and regularity, which are multifaceted and complex. One of them is the system of ensuring the quality of aviation fuel for refueling aircraft at airports. A significant influence of the quality, chemical composition and fuel range on the reliability and lifetime of components and parts of the aircraft fuel system was studied in the process of development and experience accumulation of aircraft operating, processes of aviation fuel production, as well as during storage, quality control, transportation, refueling preparation and aircraft refueling. Currently, work is being done to study the influence of fuel quality on the units of the technological scheme of fuel-filling complexes, which provide the required cleanliness of the fuel according to the regulations. The article describes the trend level of aviation fuel cleanliness at the stages from receipt to issuance to the refueling station. The evaluation of compliance with existing regulations on the level of jet fuel cleanliness and the efficiency of fuel cleaning facilities is carried out. It is stated that one of the problems of insufficient level of aviation fuel cleaning quality is a violation of the acceptable contamination level of the fuel before the filter. It was found that the disadvantage of the used filter paper is the fiber wash out process. According to this research it was found that while cleaning fuel from mechanical admixtures it is necessary to take into account the technical condition of the filtering element, and proposal was developed for fuel-filling systems to ensure aviation fuel cleanliness in compliance with regulations.

Preliminary design of four aircraft to service the California Corridor in the year 2010: The California Condor, California Sky-Hopper, high capacity short range transport tilt rotor aircraft needed to simplify intercity transportation

Science.gov (United States)

1989-01-01

The major objective of this project was to design an aircraft for use in the California Corridor in the year 2010. The design process, completed by students in a senior design class at California Polytechnic State University, San Luis Obispo, used a Class 1 airplane design analysis from Jan Roskam's Airplane Design. The California Condor (CC-38), a 38 passenger, 400 mph aircraft, was designed to meet the needs of tomorrow's passengers while conforming to the California Corridor's restrictions. Assumptions were made using today's technology with forecasts into 21st Century technology. Doubling today's commuter aircraft passenger capacity, travelling at Mach .57 with improved cruise efficiencies of over 10 percent, with the ability to land within field lengths of 4000 feet, are the CC-38's strongest points. The California Condor has a very promising future in helping to relieve the air traffic and airport congestion in the 21st Century.

Effect of Stress Ratio on Fatigue Crack Growth Rate at Notched Hole in 7075-T6 Aluminum Alloy Under Biaxial Fatigue

Science.gov (United States)

2016-08-18

Berezhnitski, L.T., and R.S. Gromyak. “Evaluation of Limiting State of Matrix in Vicinity of Sharp-Edge Rigid Inclusion.” Material Science, Volume 13...Effect of Surface Enhancement on the Corrosion Properties, Fatigue Strength, and Degradation Of Aircraft Aluminum.” Lambda Research, 2010. [38

THE COMPLEX OF STANDS FOR TESTING THE AIR CUSHION CHASSIS OF AIRCRAFT AND VEHICLES

Directory of Open Access Journals (Sweden)

2016-01-01

Full Text Available This article deals with a set of stands made in NIMK TSAGI for testing and creating the air cushion chassis for the aircraft and vehicles. It allows to fully embrace the process of developing and constructing the air cushion chassis for air- craft and solve problems relating to peculiarities of such aircraft on the takeoff, landing and movement in the elementary prepared and unprepared soil runways, flat terrain and water areas. The complex includes: the experimental installation to study aeroelasticity phenomena of the chassis in the extending and retracting process with simulation of aircraft and ekran- oplane takeoff and landing modes in the air flow, including the wind tunnels; the experimental stand with vertical screen for testing of ekranoplane models in T-5 wind tunnel of NIMC TsAGI, permitting to simultaneously vary the model’s posi- tion relatively to the screen, roll, pitch (angle of attack, and banking; mobile experimental stand with contact crawler gear, for experimental determination and comparative evaluation of the chassis with different patterns of formation and air cush- ion fences for all-year-round testing in natural conditions at elementary-prepared and unprepared sites and water areas. Based on mathematical simulation of flow past in the wind tunnel the possibility of use booth stand with vertical screen and experimental installation to study aeroelasticity phenomena of the chassis for experimental studies, respectively, by defini- tion of the aerodynamic characteristics of forces and moments of the air cushion aircraft and ekranoplanes models and the research of phenomena of aeroelasticity of flexible fencing is substantiated.

Tasting Pseudomonas aeruginosa biofilms.Human neutrophils express the bitter receptor T2R38 as sensor for the quorum sensing molecule N-(3-oxododecanoyl-L-homoserine lactone

Directory of Open Access Journals (Sweden)

Susanne eMaurer

2015-07-01

Full Text Available Bacteria communicate with each other via specialized signalling molecules, known as quorum sensing molecules or autoinducers. The Pseudomonas aeruginosa-derived quorum sensing molecule N-(3-oxododecanoyl-L-homoserine lactone (AHL-12, however, also activates mammalian cells. As shown previously, AHL-12 induced chemotaxis, up-regulated CD11b expression, and enhanced phagocytosis of polymorphonuclear neutrophils (PMN. Circumstantial evidence concurred with a receptor for AHL-12, which so far has been elusive. We investigated the bitter receptor T2R38 as a potential candidate. Although identified as a taste receptor, cells outside the gustatory system express T2R38, for example epithelial cells in the lung. We now detected T2R38 in peripheral blood neutrophils, monocytes and lymphocytes on the cell membrane, but also intracellular. In neutrophils, T2R38 was located in vesicles with characteristics of lipid droplets, and super-resolution microscopy showed a co-localisation with the lipid droplet membrane. Neutrophils take up AHL-12, and it co-localized with T2R38 as seen by laser scan microscopy. Binding of AHL-12 to T2R28 was confirmed by pull-down assays using biotin-coupled AHL-12 as bait. A commercially available antibody to T2R38 inhibited binding of AHL-12 to neutrophils, and this antibody by itself stimulated neutrophils, similarly to AHL-12. In conclusion, our data provide evidence for expression of functional T2R38 on neutrophils, and are compatible with the notion that T2R38 is the receptor for AHL-12 on neutrophils.

Effect of Localized Corrosion on Fatigue-Crack Growth in 2524-T3 and 2198-T851 Aluminum Alloys Used as Aircraft Materials

Science.gov (United States)

Moreto, J. A.; Broday, E. E.; Rossino, L. S.; Fernandes, J. C. S.; Bose Filho, W. W.

2018-03-01

Corrosion and fatigue of aluminum alloys are major issues for the in-service life assessment of aircraft structures and for the management of aging air fleets. The aim of this work was to evaluate the effect of localized corrosion on fatigue crack growth (FCG) resistance of the AA2198-T851 Al-Li alloy (Solution Heat Treated, Cold Worked, and Artificially Aged), comparing it with the FCG resistance of AA2524-T3 (Solution Heat Treated and Cold Worked), considering the effect of seawater fog environment. Before fatigue tests, the corrosion behavior of 2198-T851 and 2524-T3 aluminum alloys was verified using open circuit potential and potentiodynamic polarization techniques. Fatigue in air and corrosion fatigue tests were performed applying a stress ratio (R) of 0.1, 15 Hz (air) and 0.1 Hz (seawater fog) frequencies, using a sinusoidal waveform in all cases. The results showed that the localized characteristics of the 2198-T851 and 2524-T3 aluminum alloys are essentially related to the existence of intermetallic compounds, which, due to their different nature, may be cathodic or anodic in relation to the aluminum matrix. The corrosive medium has affected the FCG rate of both aluminum alloys, in a quite similar way.

78 FR 56150 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

Science.gov (United States)

2013-09-12

... Airworthiness Directives; Piper Aircraft, Inc. Airplanes AGENCY: Federal Aviation Administration (FAA), DOT... published in the Federal Register. AD 2013-13-01 applies to certain Piper Aircraft, Inc. Models PA-46-310P... nitrile parts are installed for certain Piper Aircraft, Inc. Models PA-46-310P, PA-46-350P, PA-46R-350T...

Transport aircraft loading and balancing system: Using a CLIPS expert system for military aircraft load planning

Science.gov (United States)

Richardson, J.; Labbe, M.; Belala, Y.; Leduc, Vincent

1994-01-01

The requirement for improving aircraft utilization and responsiveness in airlift operations has been recognized for quite some time by the Canadian Forces. To date, the utilization of scarce airlift resources has been planned mainly through the employment of manpower-intensive manual methods in combination with the expertise of highly qualified personnel. In this paper, we address the problem of facilitating the load planning process for military aircraft cargo planes through the development of a computer-based system. We introduce TALBAS (Transport Aircraft Loading and BAlancing System), a knowledge-based system designed to assist personnel involved in preparing valid load plans for the C130 Hercules aircraft. The main features of this system which are accessible through a convivial graphical user interface, consists of the automatic generation of valid cargo arrangements given a list of items to be transported, the user-definition of load plans and the automatic validation of such load plans.

3D flyable curves for an autonomous aircraft

Science.gov (United States)

Bestaoui, Yasmina

2012-11-01

The process of conducting a mission for an autonomous aircraft includes determining the set of waypoints (flight planning) and the path for the aircraft to fly (path planning). The autonomous aircraft is an under-actuated system, having less control inputs than degrees of freedom and has two nonholonomic (non integrable) kinematic constraints. Consequently, the set of feasible trajectories will be restricted and the problem of trajectory generation becomes more complicated than a simple interpolation. Care must be taken in the selection of the basic primitives to respect the kinematic and dynamic limitations. The topic of this paper is trajectory generation using parametric curves. The problem can be formulated as follows: to lead the autonomous aircraft from an initial configuration qi to a final configuration qf in the absence of obstacles, find a trajectory q(t) for 0 ≤t ≤ T. The trajectory can be broken down into a geometric path q(s), s being the curvilinear abscissa and s=s(t) a temporal function. In 2D the curves fall into two categories: • Curves whose coordinates have a closed form expressions, for example B-splines, quintic polynomials or polar splines. • Curves whose curvature is a function of their arc length for example clothoids, cubic spirals, quintic or intrinsic splines. Some 3D solutions will be presented in this paper and their effectiveness discussed towards the problem in hand.

Human and behavioral factors contributing to spine-based neurological cockpit injuries in pilots of high-performance aircraft: recommendations for management and prevention

Science.gov (United States)

Jones, J. A.; Hart, S. F.; Baskin, D. S.; Effenhauser, R.; Johnson, S. L.; Novas, M. A.; Jennings, R.; Davis, J.

2000-01-01

In high-performance aircraft, the need for total environmental awareness coupled with high-g loading (often with abrupt onset) creates a predilection for cervical spine injury while the pilot is performing routine movements within the cockpit. In this study, the prevalence and severity of cervical spine injury are assessed via a modified cross-sectional survey of pilots of multiple aircraft types (T-38 and F-14, F-16, and F/A-18 fighters). Ninety-five surveys were administered, with 58 full responses. Fifty percent of all pilots reported in-flight or immediate post-flight spine-based pain, and 90% of fighter pilots reported at least one event, most commonly (> 90%) occurring during high-g (> 5 g) turns of the aircraft with the head deviated from the anatomical neutral position. Pre-flight stretching was not associated with a statistically significant reduction in neck pain episodes in this evaluation, whereas a regular weight training program in the F/A-18 group approached a significant reduction (mean = 2.492; p < 0.064). Different cockpit ergonomics may vary the predisposition to cervical injury from airframe to airframe. Several strategies for prevention are possible from both an aircraft design and a preventive medicine standpoint. Countermeasure strategies against spine injury in pilots of high-performance aircraft require additional research, so that future aircraft will not be limited by the human in control.

77 FR 68061 - Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters

Science.gov (United States)

2012-11-15

... Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters AGENCY: Federal Aviation Administration (FAA... Aircraft Corporation (Sikorsky) Model S-92A helicopters. This AD requires inspecting the tail rotor (T/R... Corporation, Attn: Manager, Commercial Technical Support, mailstop s581a, 6900 Main Street, Stratford, CT...

Hydrogen aircraft and airport safety

International Nuclear Information System (INIS)

Schmidtchen, U.; Behrend, E.; Pohl, H.-W.; Rostek, N.

1997-01-01

First flight tests with a hydrogen demonstrator aircraft, currently under investigation in the scope of the German-Russia Cryoplane project, are scheduled for 1999. Regular service with regional aircraft may begin around 2005, followed by larger Airbus-type airliners around 2010-2015. The fuel storage aboard such airliners will be of the order of 15 t or roughly 200 m 3 LH 2 . This paper investigates a number of safety problems associated with the handling and air transport of so much hydrogen. The same is done for the infrastructure on the airport. Major risks are identified, and appropriate measures in design and operation are recommended. It is found that hydrogen aircraft are no more dangerous than conventional ones - safer in some respects. (author)

Catalytic Reactor for Inerting of Aircraft Fuel Tanks

Science.gov (United States)

1974-06-01

Aluminum Panels After Triphase Corrosion Test 79 35 Inerting System Flows in Various Flight Modes 82 36 High Flow Reactor Parametric Data 84 37 System...AD/A-000 939 CATALYTIC REACTOR FOR INERTING OF AIRCRAFT FUEL TANKS George H. McDonald, et al AiResearch Manufacturing Company Prepared for: Air Force...190th Street 2b. GROUP Torrance, California .. REPORT TITLE CATALYTIC REACTOR FOR INERTING OF AIRCRAFT FUEL TANKS . OESCRIP TIVE NOTEs (Thpe of refpoft

2018-04-23T19:38:36Z https://www.ajol.info/index.php/all/oai oai:ojs ...

African Journals Online (AJOL)

article/15320 2018-04-23T19:38:36Z ajst:ART IMPROVED COMBUSTION PROCESSES IN MEDICAL WASTES INCINERATORS FOR RURAL APPLICATIONS Ketlogetswe, C; Department of Mechanical Engineering , University of Botswana, ...

38 CFR 36.4251 - Loans to finance the purchase of manufactured homes and the cost of necessary site preparation.

Science.gov (United States)

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Loans to finance the purchase of manufactured homes and the cost of necessary site preparation. 36.4251 Section 36.4251 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) LOAN GUARANTY Guaranty of Loans to Veterans to Purchase Manufactured...

CFD Analysis of a T-38 Wing Fence

Science.gov (United States)

2007-06-01

or making major adjustments to the existing airframe. The answer lies in flow control. Flow control devices like vortex generators, winglets , and wing...fences have been used to improve the aerodynamic performance of hundreds of aircraft. Flow control is commonly added after the final phase of design...proposed by the Air Force Test Pilot School. The driving force for considering a wing fence as opposed to vane vortex generators or winglets 3 was a row of

Au ₃₈ (SPh) ₂₄ : Au ₃₈ Protected with Aromatic Thiolate Ligands

Energy Technology Data Exchange (ETDEWEB)

Rambukwella, Milan; Burrage, Shayna; Neubrander, Marie; Baseggio, Oscar; Aprà, Edoardo; Stener, Mauro; Fortunelli, Alessandro; Dass, Amala

2017-03-21

Au38(SR)24 is one of the most extensively investigated gold nanomolecules along with Au25(SR)18 and Au144(SR)60. However, so far it has only been prepared using aliphatic-like ligands, where R = –SC6H13, -SC12H25 and –SCH2CH2Ph. Au38(SCH2CH2Ph)24 when reacted with HSPh undergoes core-size conversion to Au36(SPh)24, and existing literature suggest that Au38(SPh)24 cannot be synthesized. Here, contrary to prevailing knowledge, we demonstrate that Au38(SPh)24 can be prepared if the ligand exchanged conditions are optimized, without any formation of Au36(SPh)24. Conclusive evidence is presented in the form of MALDI-MS, ESI-MS characterization, and optical spectra of Au38(SPh)24 in a solid glass form showing distinct differences from that of Au38(S-aliphatic)24. Theoretical analysis confirms experimental assignment of the optical spectrum and shows that the stability of Au38(SPh)24 is comparable to that of its aliphatic analogues, but results from different physical origins, with a significant component of ligand-ligand attractive interactions.

Aircraft Icing Handbook. Volume 1

Science.gov (United States)

1991-03-01

Maryland - . . . Kohiman Aviation, Lawrence , Kansas Ohio State University, Columbus, Ohio .I --- t-r 1-- - -t I.Q,,- t ../e . Pratt and Whitney...lower; about six percent at -22 ’F (-30 *C). 1.2.3 Variations with Season The summer or warm season months create large warm air masses which can...on Aircraft Surfaces," NASA TM 87184, May 1986. 2-54 Hausman , R.J. and Turnock, S.R., "Investigation of Surface Water Behavior During Glaze Ice

Offsite radiological consequence analysis for the bounding aircraft crash accident

International Nuclear Information System (INIS)

OBERG, B.D.

2003-01-01

The purpose of this calculation note is to quantitatively analyze a bounding aircraft crash accident for comparison to the DOE-STD-3009-94, ''Preparation Guide for U.S. Department of Energy Nonreactor Nuclear Facility Documented Safety Analyses'', Appendix A, Evaluation Guideline of 25 rem. The potential of aircraft impacting a facility was evaluated using the approach given in DOE-STD-3014-96, ''Accident Analysis for Aircraft Crash into Hazardous Facilities''. The following aircraft crash FR-equencies were determined for the Tank Farms in RPP-11736, ''Assessment Of Aircraft Crash FR-equency For The Hanford Site 200 Area Tank Farms'': (1) The total aircraft crash FR-equency is ''extremely unlikely.'' (2) The general aviation crash FR-equency is ''extremely unlikely.'' (3) The helicopter crash FR-equency is ''beyond extremely unlikely.'' (4) For the Hanford Site 200 Areas, other aircraft type, commercial or military, each above ground facility, and any other type of underground facility is ''beyond extremely unlikely.'' As the potential of aircraft crash into the 200 Area tank farms is more FR-equent than ''beyond extremely unlikely,'' consequence analysis of the aircraft crash is required

78 FR 41277 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

Science.gov (United States)

2013-07-10

... Airworthiness Directives; Piper Aircraft, Inc. Airplanes AGENCY: Federal Aviation Administration (FAA), DOT... certain Piper Aircraft, Inc. Models PA-46-310P, PA-46-350P, PA-46R-350T, and PA-46-500TP airplanes. This... through Friday, except Federal holidays. For service information identified in this AD, contact Piper...

Information note about the protection of nuclear facilities against aircraft crashes

International Nuclear Information System (INIS)

2001-01-01

The protection of nuclear facilities against external risks (earthquakes, floods, fires etc..) is an aspect of safety taken into consideration by the French authority of nuclear safety (ASN). Concerning the aircraft crashes, the fundamental safety rules make three categories of aircraft: the small civil aircraft (weight 5.7 t). Nuclear facilities are designed to resist against crashes of aircraft from the first category only, because the probability of the accidental crash of a big aircraft are extremely low. This document comprises an information note about the protection of nuclear facilities against aircraft crashes, a dossier about the safety of nuclear facilities with respect to external risks in general (natural disasters and aircraft crashes), and an article about the protection of nuclear power plants against aircraft crashes (design, safety measures, regulation, surveillance, experience feedback). (J.S.)

V/STOL tilt rotor aircraft study. Volume 2: Preliminary design of research aircraft

Science.gov (United States)

1972-01-01

A preliminary design study was conducted to establish a minimum sized, low cost V/STOL tilt-rotor research aircraft with the capability of performing proof-of-concept flight research investigations applicable to a wide range of useful military and commercial configurations. The analysis and design approach was based on state-of-the-art methods and maximum use of off-the-shelf hardware and systems to reduce development risk, procurement cost and schedules impact. The rotors to be used are of 26 foot diameter and are the same as currently under construction and test as part of NASA Tilt-Rotor Contract NAS2-6505. The aircraft has a design gross weight of 12,000 lbs. The proposed engines to be used are Lycoming T53-L-13B rated at 1550 shaft horsepower which are fully qualified. A flight test investigation is recommended which will determine the capabilities and limitations of the research aircraft.

Integrating the Base of Aircraft Data (BADA) in CTAS Trajectory Synthesizer

Science.gov (United States)

Abramson, Michael; Ali, Kareem

2012-01-01

The Center-Terminal Radar Approach Control (TRACON) Automation System (CTAS), developed at NASA Ames Research Center for assisting controllers in the management and control of air traffic in the extended terminal area, supports the modeling of more than four hundred aircraft types. However, 90% of them are supported indirectly by mapping them to one of a relatively few aircraft types for which CTAS has detailed drag and engine thrust models. On the other hand, the Base of Aircraft Data (BADA), developed and maintained by Eurocontrol, supports more than 300 aircraft types, about one third of which are directly supported, i.e. they have validated performance data. All these data were made available for CTAS by integrating BADA version 3.8 into CTAS Trajectory Synthesizer (TS). Several validation tools were developed and used to validate the integrated code and to evaluate the accuracy of trajectory predictions generated using CTAS "native" and BADA Aircraft Performance Models (APM) comparing them with radar track data. Results of these comparisons indicate that the two models have different strengths and weaknesses. The BADA APM can improve the accuracy of CTAS predictions at least for some aircraft types, especially small aircraft, and for some flight phases, especially climb.

Airsickness and aircraft motion during short-haul flights.

Science.gov (United States)

Turner, M; Griffin, M J; Holland, I

2000-12-01

There is little quantitative information that can be used to predict the incidence of airsickness from the motions experienced in military or civil aviation. This study examines the relationship between low-frequency aircraft motion and passenger sickness in short-haul turboprop flights within the United Kingdom. A questionnaire survey of 923 fare-paying passengers was conducted on 38 commercial airline flights. Concurrent measurements of aircraft motion were made on all journeys, yielding approximately 30 h of aircraft motion data. Overall, 0.5% of passengers reported vomiting, 8.4% reported nausea (range 0% to 34.8%) and 16.2% reported illness (range 0% to 47.8%) during flight. Positive correlations were found between the percentage of passengers who experienced nausea or felt ill and the magnitude of low-frequency lateral and vertical motion, although neither motion uniquely predicted airsickness. The incidence of motion sickness also varied with passenger age, gender, food consumption and activity during air travel. No differences in sickness were found between passengers located in different seating sections of the aircraft, or as a function of moderate levels of alcohol consumption. The passenger responses suggest that a useful prediction of airsickness can be obtained from magnitudes of low frequency aircraft motion. However, some variations in airsickness may also be explained by individual differences between passengers and their psychological perception of flying.

Stereosequence distributions of poly(t-butyl methacrylate)s prepared with butyllithium

International Nuclear Information System (INIS)

Suzuki, Toshimitsu; Yamada, Osamu; Watanabe, Yoshihisa; Takegami, Yoshinobu

1982-01-01

13 C NMR spectra of poly(t-butyl methacrylate)s (PBMA) prepared with butyl-lithium (n-BuLi) were studied. Methylene carbon resonances appeared as five overlapped peaks, which were interpreted as a combination of hexad stereosequence distributions. The stereosequence distribution of PBMA prepared with n-BuLi at -78 0 C obeyed the first order Markov chain model even polymerized in tetrahydrofuran (THF). Syndiotactic PBMA was obtained with azobisisobutyronitrile (AIBN) as the initiator, and the stereosequence distribution of this polymer agreed well with Bernoullian statistics. (author)

Hybrid Wing Body Aircraft Acoustic Test Preparations and Facility Upgrades

Science.gov (United States)

Heath, Stephanie L.; Brooks, Thomas F.; Hutcheson, Florence V.; Doty, Michael J.; Haskin, Henry H.; Spalt, Taylor B.; Bahr, Christopher J.; Burley, Casey L.; Bartram, Scott M.; Humphreys, William M.;

Small Engine Technology (SET) Task 24 Business and Regional Aircraft System Studies

Science.gov (United States)

Lieber, Lysbeth

2003-01-01

This final report has been prepared by Honeywell Engines & Systems, Phoenix, Arizona, a unit of Honeywell International Inc., documenting work performed during the period June 1999 through December 1999 for the National Aeronautics and Space Administration (NASA) Glenn Research Center, Cleveland, Ohio, under the Small Engine Technology (SET) Program, Contract No. NAS3-27483, Task Order 24, Business and Regional Aircraft System Studies. The work performed under SET Task 24 consisted of evaluating the noise reduction benefits compared to the baseline noise levels of representative 1992 technology aircraft, obtained by applying different combinations of noise reduction technologies to five business and regional aircraft configurations. This report focuses on the selection of the aircraft configurations and noise reduction technologies, the prediction of noise levels for those aircraft, and the comparison of the noise levels with those of the baseline aircraft.

In-flight observation of long duration gamma-ray glows by aircraft

Science.gov (United States)

Kochkin, Pavlo; (Lex) van Deursen, A. P. J.; de Boer, Alte; Bardet, Michiel; Allasia, Cedric; Boissin, Jean Francois; Ostgaard, Nikolai

2017-04-01

The Gamma-Ray Glow is a long-lasting (several seconds to minutes) X- and gamma radiation presumably originated from high-electric field of thunderclouds. Such glows were previously observed by aircraft, balloons, and from the ground. When detected on ground with other particles, i.e. electrons and neutrons, they are usually called Thunderstorm Ground Enhancements (TGEs). Their measured spectra are often consistent with Relativistic Runaway Electron Avalanche (RREA) mechanism. That is why RREA is a commonly accepted explanation for their existence. The gamma-ray glows are observed to be interrupted by lightning discharge, which terminates the high-electric field region. In January 2016 an Airbus A340 factory test aircraft was performing intentional flights through thunderstorms over Northern Australia. The aircraft was equipped with a dedicated in-flight lightning detection system called ILDAS (http://ildas.nlr.nl). The system also contained two scintillation detectors each with 38x38 mm cylinder LaBr3 crystals. While being at 12 km altitude the system detected a gamma-ray flux enhancement 30 times the background counts. It lasted for 20 seconds and was abruptly terminated by a lightning flash. The flash hit the aircraft and its parameters were recorded with 10 ns sampling time including gamma radiation. Ground-based lightning detection network WWLLN detected 4 strikes in the nearby region, all in association with the same flash. The ILDAS system recorded the time-resolved spectrum of the glow. In 6 minutes, after making a U-turn, the aircraft passed the same glow region. Smaller gamma-ray enhancement was again detected. In this presentation we will show the mapped event timeline including airplane, gamma-ray glow, WWLLN, and cloud data. We will discuss the glow's properties, i.e. intensity and differential spectrum, and its possible origin. This result will also be compared to previously reported observations.

2018-02-18T07:38:13Z https://www.ajol.info/index.php/all/oai oai:ojs ...

African Journals Online (AJOL)

article/51216 2018-02-18T07:38:13Z ai:ART Sport tourism: comparing participant profiles and impact of three one-day events in South Africa Kotze, N Visser, G Sport tourism has emerged as one of the fastest-growing spheres of the leisure travel ...

STS-93 Mission Specialist Tognini and daughter prepare to board aircraft for return flight to Housto

Science.gov (United States)

1999-01-01

At the Skid Strip at the Cape Canaveral Air Station, Mission Specialist Michel Tognini of France, representing the Centre National d'Etudes Spatiales (CNES), and his daughter Tatinana prepare to board an aircraft for their return flight to Houston following the completion of the STS-93 Space Shuttle mission. Landing occurred on runway 33 at KSC's Shuttle Landing Facility on July 27 with main gear touchdown at 11:20:35 p.m. EDT. The mission's primary objective was to deploy the Chandra X-ray Observatory, which will allow scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe. This was the 95th flight in the Space Shuttle program and the 26th for Columbia. The landing was the 19th consecutive Shuttle landing in Florida and the 12th night landing in Shuttle program history. On this mission, Eileen Collins became the first woman to serve as a Shuttle commander.

B7-H4 Treatment of T Cells Inhibits ERK, JNK, p38, and AKT Activation.

Directory of Open Access Journals (Sweden)

Xiaojie Wang

Full Text Available B7-H4 is a newly identified B7 homolog that plays an important role in maintaining T-cell homeostasis by inhibiting T-cell proliferation and lymphokine-secretion. In this study, we investigated the signal transduction pathways inhibited by B7-H4 engagement in mouse T cells. We found that treatment of CD3(+ T cells with a B7-H4.Ig fusion protein inhibits anti-CD3 elicited T-cell receptor (TCR/CD28 signaling events, including phosphorylation of the MAP kinases, ERK, p38, and JNK. B7-H4.Ig treatment also inhibited the phosphorylation of AKT kinase and impaired its kinase activity as assessed by the phosphorylation of its endogenous substrate GSK-3. Expression of IL-2 is also reduced by B7-H4. In contrast, the phosphorylation state of the TCR proximal tyrosine kinases ZAP70 and lymphocyte-specific protein tyrosine kinase (LCK are not affected by B7-H4 ligation. These results indicate that B7-H4 inhibits T-cell proliferation and IL-2 production through interfering with activation of ERK, JNK, and AKT, but not of ZAP70 or LCK.

2018-05-01T19:38:15Z https://www.ajol.info/index.php/all/oai oai:ojs ...

African Journals Online (AJOL)

article/35403 2018-05-01T19:38:15Z afsci:ART Contamination en métaux traces des ... Les résultats obtenus montrent que les concentrations métalliques trouvées sont supérieures aux concentrations relevées par d\\'autres travaux sur des ...

Combat Aircraft Maneuverability.

Science.gov (United States)

1981-12-01

rodynamique, propulsion, rdsistance den structures, etc ... - lea m~thodes d’essaia an soufflerie, aur banca au aol, sur simulateurs. A un niveau de synthbse...Dunstan Graham, "Aircraft Dynamics and Automatic Control," Princeton University Press , Princeton, N.J., 1973. 9. Hoh, Roger H., Thomas T. Myers...discussion of the roll coupling problem" Progress in Aerospace Sciences, Vol 15, Pergamon Press , Oxford 1974 17-8 (6] R.W. KLOPPENSTEIN "Zeroes of

Improvement in water-slurry circulation at the Chumakovskaya coal preparation plant

Energy Technology Data Exchange (ETDEWEB)

Nabokov, A.K.; Fedotov, B.P.; Mitlash, V.V.

1988-02-01

The Chumakovskaya coal preparation plant (Donetskugleobogashchenie association) was put into operation in 1935. It processes 570 t/h of coal slurry with an ash content of 38.6% and produces grade T coal for coking and power generation. Coal preparation technology used is described. Shortcomings of the system cause 130 kg of high ash slurries to be recirculated per m/sup 3/ of hydrocyclone drain. Mathematical analysis of the present process and of two improved variants is presented. The analysis permits variants for clarification of the recirculated water to be developed and evaluated and the best one to be selected. The optimum variant permits the amount of thin recirculated slurry to be reduced to 48% and the amount of granular slurry to 13%. Implementation of this variant at the Chumakovskaya coal preparation plant will ensure annual savings of 20,000 rubles.

The Effects of Temperature, Humidity and Aircraft Fluid Exposure on T800H/3900-2 Composites Bonded with AF-555M Adhesive

Science.gov (United States)

Miner, Gilda A.; Hou, Tan-Hung; Lowther, Sharon E.; Thibeault, Sheila A.; Connell, John W.; Blasini, Sheila Roman

2010-01-01

Fiber reinforced resin matrix composites and structural adhesives have found increased usage on commercial and military aircraft in recent years. Due to the lack of service history of these relatively new material systems, their long-term aging performance has not been well established. In this study, single lap shear specimens (SLS) were fabricated by secondary bonding of Scotch-Weld(TradeMark) AF-555M between pre-cured adherends comprised of T800H/3900-2 uni-directional laminates. The adherends were co-cured with wet peel-ply for surface preparation. Each bond-line of the SLS specimen was measured to determine thickness and inspected visually using an optical microscope for voids. A three-year environmental aging plan for the SLS specimens at 82 C (180 F) and 85% relative humidity was initiated. SLS strengths were measured for both controls and aged specimens at room temperature and 82 C. The effect of this exposure on lap shear strength and failure modes to date is reported. In addition, the effects of water, saline water, deicing fluid, JP-5 jet fuel and hydraulic fluid on both the composite material and the adhesive bonds were investigated. The up to date results on the effects of these exposures will be discussed.

A flight investigation of the ultra-deep-stall descent and spin recovery characteristics of a 1/6 scale radiocontrolled model of the Piper PA38 Tomahawk

Science.gov (United States)

Blanchard, W. S., Jr.

1981-01-01

Ultradeep stall descent and spin recovery characteristics of a 1/6 scale radio controlled model of the Piper PA38 Tomahawk aircraft was investigated. It was shown that the full scale PA38 is a suitable aircraft for conducting ultradeep stall research. Spin recovery was accomplished satisfactorily by entry to the ultradeep stall mode, followed by the exit from the ultradeep stall mode. It is concluded that since the PA38 has excellent spin recovery characteristics using normal recovery techniques (opposite rudder and forward control colum pressure), recovery using ultradeep stall would be beneficial only if the pilot suffered from disorientation.

THE KINETICS OF CONTAMINANTS ACCUMULATION IN THE JET FUEL DURING THE TECHNOLOGICAL PROCESS OF ITS PREPARATION FOR AIRCRAFT REFUELING

OpenAIRE

A. A. Brailko

2017-01-01

Much attention is payed to the tasks for ensuring domestic and international aircraft safety and regularity, which are multifaceted and complex. One of them is the system of ensuring the quality of aviation fuel for refueling aircraft at airports. A significant influence of the quality, chemical composition and fuel range on the reliability and lifetime of components and parts of the aircraft fuel system was studied in the process of development and experience accumulation of aircraft operati...

Risk assessment of aircraft accidents anywhere near an airport

International Nuclear Information System (INIS)

Barbaran, Gustavo; Jensen Mariani Santiago Nicolas

2011-01-01

This work analyzes the more suitable areas to build new facilities, taking into account the conditions imposed by an airport located nearby. Initially, it describes the major characteristics of the airport. Then, the restrictions imposed to ensure the normal operation of the aircraft are analyzed. Following, there is a summary of the evolution of studies of aircraft accidents at nuclear facilities. In the second part, three models of aircraft crash probabilities are presented, all of them developed in the U.S.A, each with an increasing level of complexity in modeling the likelihood of accidents. The first model is the 'STD-3014' Department of Energy (DOE), the second is the 'ACRAM'(Aircraft Crash Risk Assessment Methodology) prepared by the 'Lawrence Livermore National Laboratory'(LLNL) and finally the more advanced 'ACRP-3', produced by the 'Transportation Research Board'. The results obtained with the three models establish that the risks imposed on the airport vicinity, remain low due to the improvement and innovation in the aircraft's safety, reducing the risk margin for the location of new nuclear facilities near an airport. (author) [es

RETRACTED ARTICLE: Validation of mean and turbulent parameters measured from the aircraft in the marine atmospheric boundary layer

Science.gov (United States)

Kwon, Byung Hyuk; Lee, Gyuwon

2010-11-01

The SEMAPHORE (Structure des Echanges Mer-Atmosphère, Propriétés Océaniques/ Recherche Expérimentale) experiment, which took place between 04 Oct. and 17 Nov. 1993, was conducted over the oceanic Azores current located in the Azores basin. The SST (Sea Surface Temperature) field was characterized in the SEMAPHORE area (31°-38°N; 21°-28°W) by a large meander with a SST gradient of about 1°C per 100 km. In order to study the evolution of the MABL (Marine Atmospheric Boundary Layer) over the ocean, the mean and the turbulent data were evaluated by the measurement with two aircraft and a ship in different meteorological conditions. Three cases of low pressure and three cases of high pressure are mainly presented here. For the six cases, the satellite images (NOAA) did not show any relation between the SST field and the cloud cover. At each flight level, the decrease of the SST with the altitude due to the divergence of the infrared radiation flux from the ocean is 0.25°C per 100 m. For the comparison between the two aircraft, the mean thermodynamic and dynamic parameters show a good agreement except for the temperature. The dispersion of the sensible heat flux is larger than that of the latent heat flux due to the weak sensible heat flux over the ocean both in the intercomparison between two aircraft and in the comparison between the aircraft and the ship.

Vulnerability Analysis of the MAVLink Protocol for Command and Control of Unmanned Aircraft

Science.gov (United States)

2013-03-27

Patton, Nikos Karapanos, Lorenz Meier, Peter Schwabe, Andrew Tridgell, Michael Oborne, Dr. Gareth Owen, and Capt Matthew Vincie, all of whom greatly...Frew and T. Brown . Networking Issues For Small Unmanned Aircraft Systems. In Unmanned Aircraft Systems : International Symposium on Unmanned Aerial

Nonparametric method for failures detection and localization in the actuating subsystem of aircraft control system

Science.gov (United States)

Karpenko, S. S.; Zybin, E. Yu; Kosyanchuk, V. V.

2018-02-01

In this paper we design a nonparametric method for failures detection and localization in the aircraft control system that uses the measurements of the control signals and the aircraft states only. It doesn’t require a priori information of the aircraft model parameters, training or statistical calculations, and is based on algebraic solvability conditions for the aircraft model identification problem. This makes it possible to significantly increase the efficiency of detection and localization problem solution by completely eliminating errors, associated with aircraft model uncertainties.

β1-Adrenoceptor autoantibodies from DCM patients enhance the proliferation of T lymphocytes through the β1-AR/cAMP/PKA and p38 MAPK pathways.

Directory of Open Access Journals (Sweden)

Yunhui Du

Full Text Available Autoantibodies against the second extracellular loop of the β(1-adrenergic receptor (β(1-AA not only contribute to increased susceptibility to heart failure, but also play a causative role in myocardial remodeling through their sympathomimetic-like effects that are induced upon binding to the β(1-adrenergic receptor. However, their role in the function of T lymphocytes has never been previously investigated. Our present study was designed to determine whether β(1-AA isolated from the sera of dilated cardiomyopathy (DCM patients caused the proliferation of T cells and the secretion of cytokines.Blood samples were collected from 95 DCM patients as well as 95 healthy subjects, and β(1-AA was detected using ELISA. The CD3(+T lymphocytes were selected separately through flow cytometry and the effect of β(1-AA on T lymphocyte proliferation was examined by CCK-8 kits and CFSE assay. Western blotting was used to analyze the expressions of phospho-VASP and phospho-p38 MAPK.β(1-AA enhanced the proliferation of T lymphocytes. This effect could be blocked by the selective β(1-adrenergic receptor antagonist metoprolol, PKA inhibitor H89, and p38 MAPK inhibitor SB203580. Furthermore, the expression of the phosphorylated forms of phospho-VASP and phospho-p38 MAPK were markedly increased in the presence of β(1-AA. β(1-AA also inhibited the secretion of interferon-γ (IFN-γ while promoting an increase in interleukin-4 (IL-4 levels.These results demonstrate that β(1-AA isolated from DCM patients binds to β(1-AR on the surface of T cells, causing changes in T-cell proliferation and secretion through the β(1-AR/cAMP/PKA and p38 MAPK pathways.

X-36 Being Prepared on Lakebed for First Flight

Science.gov (United States)

1997-01-01

Lit by the rays of the morning sunrise on Rogers Dry Lake, adjacent to NASA's Dryden Flight Research Center, Edwards, California, technicians prepare the remotely-piloted X-36 Tailless Fighter Agility Research Aircraft for its first flight in May 1997. The NASA/Boeing X-36 Tailless Fighter Agility Research Aircraft program successfully demonstrated the tailless fighter design using advanced technologies to improve the maneuverability and survivability of possible future fighter aircraft. The program met or exceeded all project goals. For 31 flights during 1997 at the Dryden Flight Research Center, Edwards, California, the project team examined the aircraft's agility at low speed / high angles of attack and at high speed / low angles of attack. The aircraft's speed envelope reached up to 206 knots (234 mph). This aircraft was very stable and maneuverable. It handled very well. The X-36 vehicle was designed to fly without the traditional tail surfaces common on most aircraft. Instead, a canard forward of the wing was used as well as split ailerons and an advanced thrust-vectoring nozzle for directional control. The X-36 was unstable in both pitch and yaw axes, so an advanced, single-channel digital fly-by-wire control system (developed with some commercially available components) was put in place to stabilize the aircraft. Using a video camera mounted in the nose of the aircraft and an onboard microphone, the X-36 was remotely controlled by a pilot in a ground station virtual cockpit. A standard fighter-type head-up display (HUD) and a moving-map representation of the vehicle's position within the range in which it flew provided excellent situational awareness for the pilot. This pilot-in-the-loop approach eliminated the need for expensive and complex autonomous flight control systems and the risks associated with their inability to deal with unknown or unforeseen phenomena in flight. Fully fueled the X-36 prototype weighed approximately 1,250 pounds. It was 19 feet

Preparation of quality control samples for its use in the radioimmunoassay de T3, T4 and TSH

International Nuclear Information System (INIS)

Lavalley E, C.; Delgado S, B.; Ruiz J, A.; Zambrano A, F.

1991-09-01

The use of quality control samples is necessary to evaluate, in a very simple way, the quality of the assays in the radioimmunoanalysis, since allows to settle down a quality control intra and inter analysis. In this work the methodology used for the preparation of these samples with low, media and high concentration for hormones related with the thyroid is shown, being obtained the following concentrations: 50, 200 and 500 ng/dl for T 3 ; 5.6, 7.8 and 14.4 μ g/dl for T 4 and 5.4, 13.4 and >50 μ U I/ml for TSH. (Author)

Development and validation of bonded composite doubler repairs for commercial aircraft.

Energy Technology Data Exchange (ETDEWEB)

Roach, Dennis Patrick; Rackow, Kirk A.

2007-07-01

repair using a substandard design and a flawed installation. In addition, the new Sol-Gel surface preparation technique was evaluated. Fatigue coupon tests produced Sol-Gel results that could be compared with a large performance database from conventional, riveted repairs. It was demonstrated that not only can composite doublers perform well in severe off-design conditions (low doubler stiffness and presence of defects in doubler installation) but that the Sol-Gel surface preparation technique is easier and quicker to carry out while still producing optimum bonding properties. Nondestructive inspection (NDI) methods were developed so that the potential for disbond and delamination growth could be monitored and crack growth mitigation could be quantified. The NDI methods were validated using full-scale test articles and the FedEx aircraft installations. It was demonstrated that specialized NDI techniques can detect flaws in composite doubler installations before they reach critical size. Probability of Detection studies were integrated into the FedEx training in order to quantify the ability of aircraft maintenance depots to properly monitor these repairs. In addition, Boeing Structural Repair and Nondestructive Testing Manuals were modified to include composite doubler repair and inspection procedures. This report presents the results from the FedEx Pilot Program that involved installation and surveillance of numerous repairs on operating aircraft. Results from critical NDI evaluations are reported in light of damage tolerance assessments for bonded composite doublers. This work has produced significant interest from airlines and aircraft manufacturers. The successful Pilot Program produced flight performance history to establish the durability of bonded composite patches as a permanent repair on commercial aircraft structures. This report discusses both the laboratory data and Pilot Program results from repair installations on operating aircraft to introduce composite

41 CFR 102-33.315 - What are the procedures for mutilating unsalvageable aircraft parts?

Science.gov (United States)

2010-07-01

... Advisory Circular 21-38, “Disposition of Unsalvageable Aircraft Parts and Materials,” available from the... Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT..., remove the serial/lot/part numbers, and cut, crush, grind, melt, burn, or use other means to prevent the...

Database on aircraft accidents

International Nuclear Information System (INIS)

Nishio, Masahide; Koriyama, Tamio

2012-09-01

The Reactor Safety Subcommittee in the Nuclear Safety and Preservation Committee published the report 'The criteria on assessment of probability of aircraft crash into light water reactor facilities' as the standard method for evaluating probability of aircraft crash into nuclear reactor facilities in July 2002. In response to the report, Japan Nuclear Energy Safety Organization has been collecting open information on aircraft accidents of commercial airplanes, self-defense force (SDF) airplanes and US force airplanes every year since 2003, sorting out them and developing the database of aircraft accidents for latest 20 years to evaluate probability of aircraft crash into nuclear reactor facilities. This year, the database was revised by adding aircraft accidents in 2010 to the existing database and deleting aircraft accidents in 1991 from it, resulting in development of the revised 2011 database for latest 20 years from 1991 to 2010. Furthermore, the flight information on commercial aircrafts was also collected to develop the flight database for latest 20 years from 1991 to 2010 to evaluate probability of aircraft crash into reactor facilities. The method for developing the database of aircraft accidents to evaluate probability of aircraft crash into reactor facilities is based on the report 'The criteria on assessment of probability of aircraft crash into light water reactor facilities' described above. The 2011 revised database for latest 20 years from 1991 to 2010 shows the followings. The trend of the 2011 database changes little as compared to the last year's one. (1) The data of commercial aircraft accidents is based on 'Aircraft accident investigation reports of Japan transport safety board' of Ministry of Land, Infrastructure, Transport and Tourism. 4 large fixed-wing aircraft accidents, 58 small fixed-wing aircraft accidents, 5 large bladed aircraft accidents and 114 small bladed aircraft accidents occurred. The relevant accidents for evaluating

14 CFR 21.6 - Manufacture of new aircraft, aircraft engines, and propellers.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Manufacture of new aircraft, aircraft... Manufacture of new aircraft, aircraft engines, and propellers. (a) Except as specified in paragraphs (b) and (c) of this section, no person may manufacture a new aircraft, aircraft engine, or propeller based on...

Database on aircraft accidents

International Nuclear Information System (INIS)

Nishio, Masahide; Koriyama, Tamio

2013-11-01

The Reactor Safety Subcommittee in the Nuclear Safety and Preservation Committee published 'The criteria on assessment of probability of aircraft crash into light water reactor facilities' as the standard method for evaluating probability of aircraft crash into nuclear reactor facilities in July 2002. In response to this issue, Japan Nuclear Energy Safety Organization has been collecting open information on aircraft accidents of commercial airplanes, self-defense force (SDF) airplanes and US force airplanes every year since 2003, sorting out them and developing the database of aircraft accidents for the latest 20 years to evaluate probability of aircraft crash into nuclear reactor facilities. In this report the database was revised by adding aircraft accidents in 2011 to the existing database and deleting aircraft accidents in 1991 from it, resulting in development of the revised 2012 database for the latest 20 years from 1992 to 2011. Furthermore, the flight information on commercial aircrafts was also collected to develop the flight database for the latest 20 years from 1992 to 2011 to evaluate probability of aircraft crash into reactor facilities. The method for developing the database of aircraft accidents to evaluate probability of aircraft crash into reactor facilities is based on the report 'The criteria on assessment of probability of aircraft crash into light water reactor facilities' described above. The 2012 revised database for the latest 20 years from 1992 to 2011 shows the followings. The trend of the 2012 database changes little as compared to the last year's report. (1) The data of commercial aircraft accidents is based on 'Aircraft accident investigation reports of Japan transport safety board' of Ministry of Land, Infrastructure, Transport and Tourism. The number of commercial aircraft accidents is 4 for large fixed-wing aircraft, 58 for small fixed-wing aircraft, 5 for large bladed aircraft and 99 for small bladed aircraft. The relevant accidents

Creative thinking of design and redesign on SEAT aircraft cabin testbed: a case study

NARCIS (Netherlands)

Tan, C.F.; Chen, W.; Rauterberg, G.W.M.

2009-01-01

this paper, the intuition approach in the design and redesign of the environmental friendly innovative aircraft cabin simulator is presented.. The aircraft cabin simulator is a testbed that used for European Project SEAT (Smart tEchnologies for Stress free Air Travel). The SEAT project aims to

Autogenic-feedback training as a treatment for airsickness in high-performance military aircraft: Two case studies

Science.gov (United States)

Cowings, Patricia S.; Toscano, William B.; Miller, Neal E.; Reynoso, Samuel

1994-01-01

The purpose of this paper is to present a detailed description of the physiological and performance responses of two military pilots undergoing a treatment for motion sickness. The treatment used, Autogenic-Feedback Training (AFT), is an operant conditioning procedure where subjects are taught to control several of their autonomic responses and thereby suppress their motion sickness symptoms. Two male, active duty military pilots (U.S. Navy and U. S. Marine Corps), ages 30 and 35, were each given twelve 30-minute training sessions. The primary criterion for success of training was the subject's ability to tolerate rotating chair motion sickness tests for progressively longer periods of time and at higher rotational velocities. A standardized diagnostic scale was used during motion sickness to assess changes in the subject's perceived malaise. Physiological data were obtained from one pilot during tactical maneuvers in an F-18 aircraft after completion of his training. A significant increase in tolerance to laboratory-induced motion sickness tests and a reduction in autonomic nervous system (ANS) response variability was observed for both subjects after training. Both pilots were successful in applying AFT for controlling their airsickness during subsequent qualification tests on F-18 and T-38 aircraft and were returned to active duty flight status.

Simultaneous Measurement of T2 and Apparent Diffusion Coefficient (T2+ADC) in the Heart With Motion-Compensated Spin Echo Diffusion-Weighted Imaging

Science.gov (United States)

Aliotta, Eric; Moulin, Kévin; Zhang, Zhaohuan; Ennis, Daniel B.

2018-01-01

Purpose To evaluate a technique for simultaneous quantitative T2 and apparent diffusion coefficient (ADC) mapping in the heart (T2+ADC) using spin echo (SE) diffusion-weighted imaging (DWI). Theory and Methods T2 maps from T2+ADC were compared with single-echo SE in phantoms and with T2-prepared (T2-prep) balanced steady-state free precession (bSSFP) in healthy volunteers. ADC maps from T2+ADC were compared with conventional DWI in phantoms and in vivo. T2+ADC was also demonstrated in a patient with acute myocardial infarction (MI). Results Phantom T2 values from T2+ADC were closer to a single-echo SE reference than T2-prep bSSFP (−2.3 ± 6.0% vs 22.2 ± 16.3%; P T2 values from T2+ADC were significantly shorter than T2-prep bSSFP (35.8 ± 3.1 vs 46.8 ± 3.8 ms; P T2+ADC and conventional motion-compensated DWI (1.39 ± 0.18 vs 1.38 ± 0.18 mm2/ms; P = N.S.). In the patient, T2 and ADC were both significantly elevated in the infarct compared with remote myocardium (T2: 40.4 ± 7.6 vs 56.8 ± 22.0; P T2+ADC generated coregistered, free-breathing T2 and ADC maps in healthy volunteers and a patient with acute MI with no cost in accuracy, precision, or scan time compared with DWI. PMID:28516485

Aircraft Impact Assessment of APR1400 Reactor Containment Building

International Nuclear Information System (INIS)

Moon, Il Hwan; Kim, Do Yeon; Kim, Jae Hee; Kim, Sang Yun

2011-01-01

The implementation of a protection to withstand aircraft impact on safety-related structures and systems is basically based on a probabilistic evaluation for each site, if the licensing body doesn't require a deterministic approach. Existing nuclear power plants in Korea were designed based on the probabilistic approach, and the aircraft impact hazard remained less than a probability of 10 -7 . However, a man-made aircraft impact have been considered as a possible external accident for the nuclear power plant. New plant designs that are to be constructed in the U.S. after July 2009 must consider the effect of impact from a large commercial aircraft according to the requirements of 10 CFR 50.150. Especially, Reactor Containment Building (RCB) housing the safety-related equipment and fuels should be protected safely against aircraft crash without perforation and scabbing failure of external wall. APR1400 RCB is constructed as a prestressed concrete containment vessel (PCCV) which is surrounded by the auxiliary building housing additional safety-related equipment and other systems. In this study, the aircraft impact analyses for the RCB are carried out using Riera forcing function and aircraft model. Considered external wall thickness is 4 ft 6 in. for the cylindrical wall and 4 ft for the dome. Actual strengths of concrete and steel are considered as the material properties. For these analyses, the dynamic increment factor and concrete aging effect are considered in accordance with NEI 07-13(2011)

The International Context of Teacher Preparation: Rejoinder to "Isn't It Time We Did Something about the Lack of Teaching Preparation in Business Doctoral Programs?"

Science.gov (United States)

Gibbs, Graham

2016-01-01

This paper, a rejoinder to "Isn't It Time We Did Something about the Lack of Teaching Preparation in Business Doctoral Programs?" by Marx et al., suggests glancing at practices outside the United States to get some perspective on the nature of the problem of why so little emphasis is placed on teaching preparation in business doctoral…

Nonparametric method for failures diagnosis in the actuating subsystem of aircraft control system

Science.gov (United States)

Terentev, M. N.; Karpenko, S. S.; Zybin, E. Yu; Kosyanchuk, V. V.

2018-02-01

In this paper we design a nonparametric method for failures diagnosis in the aircraft control system that uses the measurements of the control signals and the aircraft states only. It doesn’t require a priori information of the aircraft model parameters, training or statistical calculations, and is based on analytical nonparametric one-step-ahead state prediction approach. This makes it possible to predict the behavior of unidentified and failure dynamic systems, to weaken the requirements to control signals, and to reduce the diagnostic time and problem complexity.

An overview of practice and regulations concerning aircraft noise protection in Serbia

Directory of Open Access Journals (Sweden)

Mirković Bojana D.

2015-01-01

Full Text Available This paper gives an overview of studies and regulation concerning the issue of aircraft noise protection in Republic of Serbia. After crossing the limit of 50.000 operations in 2014, Airport 'Nikola Tesla' is classified as major airport, and with that urged to fulfill various requirements related to nose protection. Major airports are obliged to monitor noise, as well as to prepare strategic noise maps and action plans aiming to decrease number of people exposed to aircraft noise above acceptable level.

CD34+CD38dim cells in the human thymus can differentiate into T, natural killer, and dendritic cells but are distinct from pluripotent stem cells

NARCIS (Netherlands)

Res, P.; Martínez-Cáceres, E.; Cristina Jaleco, A.; Staal, F.; Noteboom, E.; Weijer, K.; Spits, H.

1996-01-01

Recently we reported that the human thymus contains a minute population of CD34+CD38dim cells that do not express the T-cell lineage markers CD2 and CD5. The phenotype of this population resembled that of CD34+CD38dim cells present in fetal liver, umbilical cord blood, and bone marrow known to be

Teaching Risk Analysis in an Aircraft Gas Turbine Engine Design Capstone Course

Science.gov (United States)

2016-01-01

support the required performance specifications (Brandt, 2004) ( Raymer , 1989). There is no specific step to treat a selected design performance...a Design Perspective, 2nd ed.: AIAA Education Series, 2004. Raymer , Daniel P. 1989. Aircraft Design: A Conceptual Approach.: AIAA Educational...Mattingly, Jack D., Heiser, William H., Pratt, David T. 2002. Aircraft Engine Design, 2nd ed.: AIAA Education Series, 2002. Drews, Robert W. 2006. The

Information note about the protection of nuclear facilities against aircraft crashes; Note d'information sur la protection des installations nucleaires contre les chutes d'avions

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-07-01

The protection of nuclear facilities against external risks (earthquakes, floods, fires etc..) is an aspect of safety taken into consideration by the French authority of nuclear safety (ASN). Concerning the aircraft crashes, the fundamental safety rules make three categories of aircraft: the small civil aircraft (weight < 5.7 t), the military aircraft, and the commercial aircraft (w > 5.7 t). Nuclear facilities are designed to resist against crashes of aircraft from the first category only, because the probability of the accidental crash of a big aircraft are extremely low. This document comprises an information note about the protection of nuclear facilities against aircraft crashes, a dossier about the safety of nuclear facilities with respect to external risks in general (natural disasters and aircraft crashes), and an article about the protection of nuclear power plants against aircraft crashes (design, safety measures, regulation, surveillance, experience feedback). (J.S.)

10th Annual Small Business Conference

Science.gov (United States)

2006-11-02

for Navy ships supra and Navy aircraft at NAVAIR in Washington, DC, i.e., OV-10 Broncos , T-2 training jets, KFIR aircraft manufactured by the Israeli...Contractors: 38,000+ Total AMC in SWA – 57,279 rese ce: cati s – 149 tates – 43 tries – 55 ers el : 53,181 tract rs: 38,000+ tal i – 57,279 4UNCLASSIFIED

Aircraft measurements within a warm conveyor belt during the T-NAWDEX-FALCON campaign

Science.gov (United States)

Schäfler, Andreas; Boettcher, Maxi; Borrmann, Stephan; Busen, Reinhold; Dörnbrack, Andreas; Grams, Christian; Kaufmann, Stefan; Klingebiel, Marcus; Lammen, Yannick; Reutter, Philipp; Rautenhaus, Marc; Schlager, Hans; Sodemann, Harald; Voigt, Christiane; Wernli, Heini

2013-04-01

Warm Conveyor Belts (WCBs) are air streams that are highly relevant for the dynamics in the mid-latitudes as they strongly influence the evolution and intensity of northern hemispheric mid-latitude weather systems. For the predictability of cyclones the representation of diabatic processes associated with latent heat release due to phase transitions of water, surface fluxes, or radiative effects are believed to be a limiting factor. Diabatic processes in cyclones strongly depend on the transport of water vapor and are mainly organized and controlled by the coherently ascending WCB air masses. In October 2012 the T-NAWDEX-Falcon (THORPEX-North Atlantic Waveguide and Downstream Impact Experiment) campaign was organized by DLR Oberpfaffenhofen and ETH Zurich. During 9 research flights over Europe in-cloud measurements in WCBs were obtained with the DLR aircraft Falcon. Lagrangian flights were conducted with the aim to measure in the same air mass during different stages of the WCB to quantify the transport of moisture and the net latent heating along WCBs and their importance for forecast errors associated with mid-latitude weather systems. Besides in-situ observations of wind, temperature and humidity to characterize the thermodynamic structure of the WCBs, a set of dropsondes was deployed to gain a complete view on the complex structure of the cyclone. This presentation gives an overview of the three successful IOPs performed during the T-NAWDEX-Falcon campaign. To address forecast uncertainty and to enable flight planning up to four days in advance of the flights novel diagnostics based on deterministic and ensemble prediction NWP data were employed during the campaign. Furthermore a number of different trajectory models were applied for this field experiment. Based on selected flights from one intensive observation period the challenging planning process of Lagrangian matches of flight paths is described and first results are presented.

77 FR 28328 - Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters

Science.gov (United States)

2012-05-14

... Corporation Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed... Corporation (Sikorsky) Model S-92A helicopters, which requires inspecting the tail rotor (T/R) pylon for a... service information identified in this proposed AD, contact Sikorsky Aircraft Corporation, Attn: Manager...

38 CFR 41.310 - Financial statements.

Science.gov (United States)

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Financial statements. 41...) AUDITS OF STATES, LOCAL GOVERNMENTS, AND NON-PROFIT ORGANIZATIONS Auditees § 41.310 Financial statements. (a) Financial statements. The auditee shall prepare financial statements that reflect its financial...

Information note about the protection of nuclear facilities against aircraft crashes; Note d'information sur la protection des installations nucleaires contre les chutes d'avions

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-07-01

The protection of nuclear facilities against external risks (earthquakes, floods, fires etc..) is an aspect of safety taken into consideration by the French authority of nuclear safety (ASN). Concerning the aircraft crashes, the fundamental safety rules make three categories of aircraft: the small civil aircraft (weight < 5.7 t), the military aircraft, and the commercial aircraft (w > 5.7 t). Nuclear facilities are designed to resist against crashes of aircraft from the first category only, because the probability of the accidental crash of a big aircraft are extremely low. This document comprises an information note about the protection of nuclear facilities against aircraft crashes, a dossier about the safety of nuclear facilities with respect to external risks in general (natural disasters and aircraft crashes), and an article about the protection of nuclear power plants against aircraft crashes (design, safety measures, regulation, surveillance, experience feedback). (J.S.)

Propulsion controlled aircraft computer

Science.gov (United States)

Cogan, Bruce R. (Inventor)

2010-01-01

A low-cost, easily retrofit Propulsion Controlled Aircraft (PCA) system for use on a wide range of commercial and military aircraft consists of an propulsion controlled aircraft computer that reads in aircraft data including aircraft state, pilot commands and other related data, calculates aircraft throttle position for a given maneuver commanded by the pilot, and then displays both current and calculated throttle position on a cockpit display to show the pilot where to move throttles to achieve the commanded maneuver, or is automatically sent digitally to command the engines directly.

T. vaginalis Infection Is Associated with Increased IL-8 and TNFr1 Levels but with the Absence of CD38 and HLADR Activation in the Cervix of ESN.

Directory of Open Access Journals (Sweden)

Olamide D Jarrett

Full Text Available Trichomonas vaginalis infection is associated with an increased risk of HIV infection in exposed-seronegative women (ESN despite their unique immune quiescent profile. It is important to understand possible mechanisms, such as recruitment of activated T cells, by which T. vaginalis could facilitate HIV infection in this population.We conducted a cross-sectional study exploring the relationships between T. vaginalis infection, inflammatory markers and T cell activation in the cervix of ESN. During scheduled study visits, participants completed a behavioral questionnaire and physical exam, including sexually transmitted infection (STI screening and collection of endocervical sponge and cytobrush specimens. T cell and monocyte phenotypes were measured in cervical cytobrush specimens using multi-parameter flow cytometry. Cervical sponge specimens were used to measure cytokines (IL-6, IL-8,IL-10, IP-10, RANTES using Luminex immunoassays and the immune activation marker soluble TNF receptor 1 using ELISA.Specimens of 65 women were tested. Twenty-one of these women were infected with T. vaginalis. T. vaginalis infection was associated with significantly increased concentrations of IL-8 (1275pg/ml vs. 566pg/ml, p=.02 and sTNFr1 (430 pg/ml vs. 264 pg/ml, p=.005. However, T. vaginalis infection was not associated with increased percent expression of CCR5+ T cells nor increased CD38 and HLADR activation compared to uninfected women. It was also not associated with increased expression of CCR5+ monocytes.Among ESN T. vaginalis infection is associated with increased levels of genital pro-inflammatory/immune activation markers IL-8 and TNFr1, but was not associated with an increased percentage of activated endocervical T cells along the CD38 and HLADR pathways. Thus, while T.vaginalis infection may result in some reversal of the immune quiescent profile of ESN, enhanced recruitment of activated CD38 and HLADR expressing CD4+ cells into the endocervix may not

X-36 Tailless Fighter Agility Research Aircraft in flight

Science.gov (United States)

1997-01-01

feet high with a wingspan of just over 10 feet. A Williams International F112 turbofan engine provided close to 700 pounds of thrust. A typical research flight lasted 35 to 45 minutes from takeoff to touchdown. A total of 31 successful research flights were flown from May 17, 1997, to November 12, 1997, amassing 15 hours and 38 minutes of flight time. The aircraft reached an altitude of 20,200 feet and a maximum angle of attack of 40 degrees. In a follow-on effort, the Air Force Research Laboratory (AFRL), Wright-Patterson Air Force Base, Ohio, contracted with Boeing to fly AFRL's Reconfigurable Control for Tailless Fighter Aircraft (RESTORE) software as a demonstration of the adaptability of the neural-net algorithm to compensate for in-flight damage or malfunction of effectors, such as flaps, ailerons and rudders. Two RESTORE research flights were flown in December 1998, proving the viability of the software approach. The X-36 aircraft flown at the Dryden Flight Research Center in 1997 was a 28-percent scale representation of a theoretical advanced fighter aircraft. The Boeing Phantom Works (formerly McDonnell Douglas) in St. Louis, Missouri, built two of the vehicles in a cooperative agreement with the Ames Research Center, Moffett Field, California.

26 CFR 1.883-1T - Exclusion of income from the international operation of ships or aircraft (temporary).

Science.gov (United States)

2010-04-01

... domestic law tax exemption for income derived from the international operation of ships or aircraft, either... from tax for profits from the operation of ships or aircraft in international transport or international traffic under the shipping and air transport or gains article of an income tax convention with the...

Noise Scaling and Community Noise Metrics for the Hybrid Wing Body Aircraft

Science.gov (United States)

Burley, Casey L.; Brooks, Thomas F.; Hutcheson, Florence V.; Doty, Michael J.; Lopes, Leonard V.; Nickol, Craig L.; Vicroy, Dan D.; Pope, D. Stuart

2014-01-01

An aircraft system noise assessment was performed for the hybrid wing body aircraft concept, known as the N2A-EXTE. This assessment is a result of an effort by NASA to explore a realistic HWB design that has the potential to substantially reduce noise and fuel burn. Under contract to NASA, Boeing designed the aircraft using practical aircraft design princip0les with incorporation of noise technologies projected to be available in the 2020 timeframe. NASA tested 5.8% scale-mode of the design in the NASA Langley 14- by 22-Foot Subsonic Tunnel to provide source noise directivity and installation effects for aircraft engine and airframe configurations. Analysis permitted direct scaling of the model-scale jet, airframe, and engine shielding effect measurements to full-scale. Use of these in combination with ANOPP predictions enabled computations of the cumulative (CUM) noise margins relative to FAA Stage 4 limits. The CUM margins were computed for a baseline N2A-EXTE configuration and for configurations with added noise reduction strategies. The strategies include reduced approach speed, over-the-rotor line and soft-vane fan technologies, vertical tail placement and orientation, and modified landing gear designs with fairings. Combining the inherent HWB engine shielding by the airframe with added noise technologies, the cumulative noise was assessed at 38.7 dB below FAA Stage 4 certification level, just 3.3 dB short of the NASA N+2 goal of 42 dB. This new result shows that the NASA N+2 goal is approachable and that significant reduction in overall aircraft noise is possible through configurations with noise reduction technologies and operational changes.

Cytotoxic effects in 3T3-L1 mouse and WI-38 human fibroblasts following 72 hour and 7 day exposures to commercial silica nanoparticles

International Nuclear Information System (INIS)

Stępnik, Maciej; Arkusz, Joanna; Smok-Pieniążek, Anna; Bratek-Skicki, Anna; Salvati, Anna; Lynch, Iseult; Dawson, Kenneth A.; Gromadzińska, Jolanta; De Jong, Wim H.; Rydzyński, Konrad

2012-01-01

The potential toxic effects in murine (3T3-L1) and human (WI-38) fibroblast cell lines of commercially available silica nanoparticles (NPs), Ludox CL (nominal size 21 nm) and CL-X (nominal size of 30 nm) were investigated with particular attention to the effect over long exposure times (the tests were run after 72 h exposure up to 7 days). These two formulations differed in physico-chemical properties and showed different stabilities in the cell culture medium used for the experiments. Ludox CL silica NPs were found to be cytotoxic only at the higher concentrations to the WI-38 cells (WST-1 and LDH assays) but not to the 3T3-L1 cells, whereas the Ludox CL-X silica NPs, which were less stable over the 72 h exposure, were cytotoxic to both cell lines in both assays. In the clonogenic assay both silica NPs induced a concentration dependent decrease in the surviving fraction of 3T3-L1 cells, with the Ludox CL-X silica NPs being more cytotoxic. Cell cycle analysis showed a trend indicating alterations in both cell lines at different phases with both silica NPs tested. Buthionine sulfoximine (γ-glutamylcysteine synthetase inhibitor) combined with Ludox CL-X was found to induce a strong decrease in 3T3-L1 cell viability which was not observed for the WI-38 cell line. This study clearly indicates that longer exposure studies may give important insights on the impact of nanomaterials on cells. However, and especially when investigating nanoparticle effects after such long exposure, it is fundamental to include a detailed physico-chemical characterization of the nanoparticles and their dispersions over the time scale of the experiment, in order to be able to interpret eventual impacts on cells. -- Highlights: ► Ludox CL silica NPs are cytotoxic to WI-38 fibroblasts but not to 3T3-L1 fibroblasts. ► Ludox CL-X silica NPs are cytotoxic to both cell lines. ► In clonogenic assay both silica NPs induce cytotoxicity, higher for CL-X silica. ► Cell cycle analysis shows

Small transport aircraft technology

Science.gov (United States)

Williams, L. J.

1983-01-01

Information on commuter airline trends and aircraft developments is provided to upgrade the preliminary findings of a NASA-formed small transport aircraft technology (STAT) team, established to determine whether the agency's research and development programs could help commuter aircraft manufacturers solve technical problems related to passenger acceptance and use of 19- to 50-passenger aircraft. The results and conclusions of the full set of completed STAT studies are presented. These studies were performed by five airplane manufacturers, five engine manufacturers, and two propeller manufacturers. Those portions of NASA's overall aeronautics research and development programs which are applicable to commuter aircraft design are summarized. Areas of technology that might beneficially be expanded or initiated to aid the US commuter aircraft manufacturers in the evolution of improved aircraft for the market are suggested.

38 CFR 21.3102 - Required counseling.

Science.gov (United States)

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Required counseling. 21.... Chapter 35 Counseling § 21.3102 Required counseling. (a) Child. The VA counseling psychologist will provide counseling and assist in preparing the educational plan only if the eligible child or his or her...

Topology Optimization of an Aircraft Wing

Science.gov (United States)

2015-06-11

which selected as the most prevalent independent structure in the wing. The tank location and shape was interpreted from the high material volume...Engineering Inc., 1820 E. Big Beaver Rd, Troy, MI 48083, Optistruct 12.0 User’s Guide, 2013. 126 10. T. Megson and H. Gordon, Aircraft structures for...software enhances the design of transportation,” Forbes Online, 2013. 13. Altair Engineering Inc., 1820 E. Big Beaver Rd, Troy, MI 48083, Hypermesh

Aircraft Weather Mitigation for the Next Generation Air Transportation System

Science.gov (United States)

Stough, H. Paul, III

2007-01-01

Atmospheric effects on aviation are described by Mahapatra (1999) as including (1) atmospheric phenomena involving air motion - wind shear and turbulence; (2) hydrometeorological phenomena - rain, snow and hail; (3) aircraft icing; (4) low visibility; and (5) atmospheric electrical phenomena. Aircraft Weather Mitigation includes aircraft systems (e.g. airframe, propulsion, avionics, controls) that can be enacted (by a pilot, automation or hybrid systems) to suppress and/or prepare for the effects of encountered or unavoidable weather or to facilitate a crew operational decision-making process relative to weather. Aircraft weather mitigation can be thought of as a continuum (Figure 1) with the need to avoid all adverse weather at one extreme and the ability to safely operate in all weather conditions at the other extreme. Realistic aircraft capabilities fall somewhere between these two extremes. The capabilities of small general aviation aircraft would be expected to fall closer to the "Avoid All Adverse Weather" point, and the capabilities of large commercial jet transports would fall closer to the "Operate in All Weather Conditions" point. The ability to safely operate in adverse weather conditions is dependent upon the pilot s capabilities (training, total experience and recent experience), the airspace in which the operation is taking place (terrain, navigational aids, traffic separation), the capabilities of the airport (approach guidance, runway and taxiway lighting, availability of air traffic control), as well as the capabilities of the airplane. The level of mitigation may vary depending upon the type of adverse weather. For example, a small general aviation airplane may be equipped to operate "in the clouds" without outside visual references, but not be equipped to prevent airframe ice that could be accreted in those clouds.

Stimulation of p38 (HOG1) kinase pathway by ionizing radiation results in downstream modulation of ATF/CREB transcription factor activity in NIH-3T3 cells

International Nuclear Information System (INIS)

Stevenson, Mary Ann; Yao Jin

1997-01-01

Purpose/Objective:p38 kinase, a member of the MAP kinase family, is activated in response to stresses such as high osmolarity and UV irradiation as well exposure to cytokines such as IL1β and TNFα. The kinase is part of a signal transduction pathway that leads from receptor activation through a three kinase cascade resulting in the activation of p38. p38 activation then leads to the phosphorylation of target proteins that include transcription factors such as nuclear factor of interleukin 6 and members of the activating transcription factor (ATF) family, and in addition, the stress protein, HSP27, via activation of MAPKAP2 kinase. In the present report, we have investigated the potential role of p38 in the response of NIH-3T3 cells to ionizing radiation. Materials and Methods:NIH-3T3 cells were grown to confluence in DMEM+10%CS and then serum deprived for 24 hours in DMEM+0.1%CS. Radiation exposures were delivered using a Philips RT250 (250Kvp X-ray tube). Activated forms of p38 kinase and ATF/CREB transcription factors were identified using immunoblotting techniques employing activation specific antibodies raised against the phosphorylated forms of the kinases/transcription factors. Kinase activity was directly measured using immunokinase assays. DNA binding of transcription factors to their respective consensus sequences was assayed by EMSA. Results:We found that p38 becomes rapidly phosphorylated and activated by exposure to ionizing radiation. Significantly, p38 is activated to a similar degree and with a similar time course by serum derpviation and entry of cells into a non-proliferating G 0 state, suggesting a causal role for p38 in quiescence. Phosphorylation of p38 directly correlated with phosphorylation and activation of ATF/CREB family members as well as DNA binding by these activated factors. Conclusion:Activation of p38 kinase and downstream transcription factors may play an important role in the response of cells to ionizing radiation. We are

Double-sided laser beam welded T-joints for aluminum-lithium alloy aircraft fuselage panels: Effects of filler elements on microstructure and mechanical properties

Science.gov (United States)

Han, Bing; Tao, Wang; Chen, Yanbin; Li, Hao

2017-08-01

In the current work, T-joints consisting of 2.0 mm thick 2060-T8/2099-T83 aluminum-lithium alloys for aircraft fuselage panels have been fabricated by double-sided fiber laser beam welding with different filler wires. A new type wire CW3 (Al-6.2Cu-5.4Si) was studied and compared with conventional wire AA4047 (Al-12Si) mainly on microstructure and mechanical properties. It was found that the main combined function of Al-6.2%Cu-5.4%Si in CW3 resulted in considerable improvements especially on intergranular strength, hot cracking susceptibility and hoop tensile properties. Typical non-dendritic equiaxed zone (EQZ) was observed along welds' fusion boundary. Hot cracks and fractures during the load were always located within the EQZ, however, this typical zone could be restrained by CW3, effectively. Furthermore, changing of the main intergranular precipitated phase within the EQZ from T phase by AA4047 to T2 phase by CW3 also resulted in developments on microscopic intergranular reinforcement and macroscopic hoop tensile properties. In addition, bridging caused by richer substructure dendrites within CW3 weld's columnar zone resulted in much lower hot cracking susceptibility of the whole weld than AA4047.

38 CFR 36.4221 - Delegation of authority.

Science.gov (United States)

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Delegation of authority. 36.4221 Section 36.4221 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... Site Preparation General Provisions § 36.4221 Delegation of authority. (a) Except as hereinafter...

Expression, purification, crystallization and preliminary X-ray diffraction analysis of Arabidopsis thaliana cyclophilin 38 (AtCyp38)

International Nuclear Information System (INIS)

Vasudevan, Dileep; Gopalan, Gayathri; He, Zengyong; Luan, Sheng; Swaminathan, Kunchithapadam

2005-01-01

Crystallization of Arabidopsis thaliana cyclophilin 38. The crystal diffracts X-rays to 2.5 Å resolution. AtCyp38 is one of the highly divergent multidomain cyclophilins from Arabidopsis thaliana. A recombinant form of AtCyp38 (residues 83–437) was expressed in Escherichia coli and purified to homogeneity. The protein was crystallized using the vapour-batch technique with PEG 6000 and t-butanol as precipitants. Crystals of recombinant AtCyp38 diffracted X-rays to better than 2.5 Å resolution at 95 K using a synchrotron-radiation source. The crystal belongs to the C-centred orthorhombic space group C222 1 , with unit-cell parameters a = 58.2, b = 95.9, c = 167.5 Å, and contains one molecule in the asymmetric unit. The selenomethionine derivative of the AtCyp38 protein was overexpressed, purified and crystallized in the same space group and data were collected to 3.5 Å at the NSLS synchrotron. The structure is being solved by the MAD method

Predicting visibility of aircraft.

Directory of Open Access Journals (Sweden)

Andrew Watson

Full Text Available Visual detection of aircraft by human observers is an important element of aviation safety. To assess and ensure safety, it would be useful to be able to be able to predict the visibility, to a human observer, of an aircraft of specified size, shape, distance, and coloration. Examples include assuring safe separation among aircraft and between aircraft and unmanned vehicles, design of airport control towers, and efforts to enhance or suppress the visibility of military and rescue vehicles. We have recently developed a simple metric of pattern visibility, the Spatial Standard Observer (SSO. In this report we examine whether the SSO can predict visibility of simulated aircraft images. We constructed a set of aircraft images from three-dimensional computer graphic models, and measured the luminance contrast threshold for each image from three human observers. The data were well predicted by the SSO. Finally, we show how to use the SSO to predict visibility range for aircraft of arbitrary size, shape, distance, and coloration.

Roles, uses, and benefits of general aviation aircraft in aerospace engineering education

Science.gov (United States)

Odonoghue, Dennis P.; Mcknight, Robert C.

1994-01-01

Many colleges and universities throughout the United States offer outstanding programs in aerospace engineering. In addition to the fundamentals of aerodynamics, propulsion, flight dynamics, and air vehicle design, many of the best programs have in the past provided students the opportunity to design and fly airborne experiments on board various types of aircraft. Sadly, however, the number of institutions offering such 'airborne laboratories' has dwindled in recent years. As a result, opportunities for students to apply their classroom knowledge, analytical skills, and engineering judgement to the development and management of flight experiments on an actual aircraft are indeed rare. One major reason for the elimination of flight programs by some institutions, particularly the smaller colleges, is the prohibitive cost of operating and maintaining an aircraft as a flying laboratory. The purpose of this paper is to discuss simple, low-cost, relevant flight experiments that can be performed using readily available general aviation aircraft. This paper examines flight experiments that have been successfully conducted on board the NASA Lewis Research Center's T-34B aircraft, as part of the NASA/AIAA/University Flight Experiment Program for Students (NAUFEPS) and discusses how similar experiments could be inexpensively performed on other general aviation aircraft.

Ghrelin protects against depleted uranium-induced apoptosis of MC3T3-E1 cells through oxidative stress-mediated p38-mitogen-activated protein kinase pathway

Energy Technology Data Exchange (ETDEWEB)

Hao, Yuhui; Liu, Cong; Huang, Jiawei; Gu, Ying; Li, Hong; Yang, Zhangyou; Liu, Jing [State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Third Military Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing 400038 (China); Wang, Weidong, E-mail: wwdwyl@sina.com [Department of Radiation Oncology, Shanghai Jiao Tong University Affiliated Sixth People Hospital, Shanghai 200233 (China); Li, Rong, E-mail: yuhui_hao@126.com [State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Third Military Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing 400038 (China)

2016-01-01

Depleted uranium (DU) mainly accumulates in the bone over the long term. Osteoblast cells are responsible for the formation of bone, and they are sensitive to DU damage. However, studies investigating methods of reducing DU damage in osteoblasts are rarely reported. Ghrelin is a stomach hormone that stimulates growth hormones released from the hypothalamic–pituitary axis, and it is believed to play an important physiological role in bone metabolism. This study evaluates the impact of ghrelin on DU-induced apoptosis of the osteoblast MC3T3-E1 and investigates its underlying mechanisms. The results show that ghrelin relieved the intracellular oxidative stress induced by DU, eliminated reactive oxygen species (ROS) and reduced lipid peroxidation by increasing intracellular GSH levels; in addition, ghrelin effectively suppressed apoptosis, enhanced mitochondrial membrane potential, and inhibited cytochrome c release and caspase-3 activation after DU exposure. Moreover, ghrelin significantly reduced the expression of DU-induced phosphorylated p38-mitogen-activated protein kinase (MAPK). A specific inhibitor (SB203580) or specific siRNA of p38-MAPK could significantly suppress DU-induced apoptosis and related signals, whereas ROS production was not affected. In addition, ghrelin receptor inhibition could reduce the anti-apoptosis effect of ghrelin on DU and reverse the effect of ghrelin on intracellular ROS and p38-MAPK after DU exposure. These results suggest that ghrelin can suppress DU-induced apoptosis of MC3T3-E1 cells, reduce DU-induced oxidative stress by interacting with its receptor, and inhibit downstream p38-MAPK activation, thereby suppressing the mitochondrial-dependent apoptosis pathway. - Highlights: • Ghrelin suppressed DU-induced apoptosis of MC3T3-E1 cells. • Ghrelin inhibited DU-induced oxidative stress and further p38-MAPK activation. • Ghrelin further suppressed mitochondrial-dependent apoptosis pathway. • The anti-oxidation effect of

Impact of aircraft systems within aircraft operation: A MEA trajectory optimisation study

OpenAIRE

Seresinhe, R.

2014-01-01

Air transport has been a key component of the socio-economic globalisation. The ever increasing demand for air travel and air transport is a testament to the success of the aircraft. But this growing demand presents many challenges. One of which is the environmental impact due to aviation. The scope of the environmental impact of aircraft can be discussed from many viewpoints. This research focuses on the environmental impact due to aircraft operation. Aircraft operation causes...

X-36 Tailless Fighter Agility Research Aircraft arrival at Dryden

Science.gov (United States)

1996-01-01

just over 10 feet. A Williams International F112 turbofan engine provided close to 700 pounds of thrust. A typical research flight lasted 35 to 45 minutes from takeoff to touchdown. A total of 31 successful research flights were flown from May 17, 1997, to November 12, 1997, amassing 15 hours and 38 minutes of flight time. The aircraft reached an altitude of 20,200 feet and a maximum angle of attack of 40 degrees. In a follow-on effort, the Air Force Research Laboratory (AFRL), Wright-Patterson Air Force Base, Ohio, contracted with Boeing to fly AFRL's Reconfigurable Control for Tailless Fighter Aircraft (RESTORE) software as a demonstration of the adaptability of the neural-net algorithm to compensate for in-flight damage or malfunction of effectors, such as flaps, ailerons and rudders. Two RESTORE research flights were flown in December 1998, proving the viability of the software approach. The X-36 aircraft flown at the Dryden Flight Research Center in 1997 was a 28-percent scale representation of a theoretical advanced fighter aircraft. The Boeing Phantom Works (formerly McDonnell Douglas) in St. Louis, Missouri, built two of the vehicles in a cooperative agreement with the Ames Research Center, Moffett Field, California.

Integral Transportation Systems in Military Transport Aircraft Supply

Directory of Open Access Journals (Sweden)

Dražen Kovačević

2012-10-01

Full Text Available Supply of goods, equipment and soldiers by militwy transportaircraft can serve as a support to airborne landing operation,support to encircled forces, and support to forces leadinga gue1rilla war. Transport aircraft are designed in such a wayas to be able to cany containers, pallets, most of land vehiclesand helicopters. Militwy transport aircraft can be grouped intothose that were originally designed for military transp01t andthose that are modified civilian aircraft and helicopters. Supplypallets can be wooden, metal, can be airdropped in "taxiing","low-flight", and can also be fitted with a parachute or"retrorocket" for reducing the ground impact. Pallets canamong other things carry liquids, heavy combat and ca1rier vehicles,artillery and rocket weapons and valious containers.Pallets are usually pe1manently deformed at ground impact.Nowadays, high precision of airdrop has been achieved. Containersare used to carry various equipment, food, fue~ weapons,ammunition etc. It is to be expected that the containers,wmoured combat and other vehicles will be redesigned so asto provide more efficient transport and fast a!Tangement ofhigh-mobility units, whereas the form of the future militarytransport aircraft will not undergo substantial changes. By adjustingand standardising the transporlation vehicles, integraltransportation means and cwgo, the overall combat efficiencywill be increased, the a~rangement time especially shortenedand the air supply safety increased.

Brazilian Air Force aircraft structural integrity program: An overview

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Alberto W. S. Mello Junior

2009-01-01

Full Text Available This paper presents an overview of the activities developed by the Structural Integrity Group at the Institute of Aeronautics and Space - IAE, Brazil, as well as the status of ongoing work related to the life extension program for aircraft operated by the Brazilian Air Force BAF. The first BAF-operated airplane to undergo a DTA-based life extension was the F-5 fighter, in the mid 1990s. From 1998 to 2001, BAF worked on a life extension project for the BAF AT- 26 Xavante trainer. All analysis and tests were performed at IAE. The fatigue critical locations (FCLs were presumed based upon structural design and maintenance data and also from exchange of technical information with other users of the airplane around the world. Following that work, BAF started in 2002 the extension of the operational life of the BAF T-25 “Universal”. The T-25 is the basic training airplane used by AFA - The Brazilian Air Force Academy. This airplane was also designed under the “safe-life” concept. As the T-25 fleet approached its service life limit, the Brazilian Air Force was questioning whether it could be kept in flight safely. The answer came through an extensive Damage Tolerance Analysis (DTA program, briefly described in this paper. The current work on aircraft structural integrity is being performed for the BAF F-5 E/F that underwent an avionics and weapons system upgrade. Along with the increase in weight, new configurations and mission profiles were established. Again, a DTA program was proposed to be carried out in order to establish the reliability of the upgraded F-5 fleet. As a result of all the work described, the BAF has not reported any accident due to structural failure on aircraft submitted to Damage Tolerance Analysis.

Graphene/Epoxy Coating as Multifunctional Material for Aircraft Structures

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Tullio Monetta

2015-06-01

Full Text Available Recently, the use of graphene as a conductive nanofiller in the preparation of inorganic/polymer nanocomposites has attracted increasing interest in the aerospace field. The reason for this is the possibility of overcoming problems strictly connected to the aircraft structures, such as electrical conductivity and thus lightning strike protection. In addition, graphene is an ideal candidate to enhance the anti-corrosion properties of the resin, since it absorbs most of the light and provides hydrophobicity for repelling water. An important aspect of these multifunctional materials is that all these improvements can be realized even at very low filler loadings in the polymer matrix. In this work, graphene nanoflakes were incorporated into a water-based epoxy resin, and then the hybrid coating was applied to Al 2024-T3 samples. The addition of graphene considerably improved some physical properties of the hybrid coating as demonstrated by Electrochemical Impedance Spectroscopy (EIS analysis, ameliorating anti-corrosion performances of raw material. DSC measurements and Cross-cut Test showed that graphene did not affect the curing process or the adhesion properties. Moreover, an increment of water contact angle was displayed.

Structure and functional regulation of the CD38 promoter

International Nuclear Information System (INIS)

Sun Li; Iqbal, Jameel; Zaidi, Samir; Zhu Linglng; Zhang Xuefeng; Peng Yuanzheng; Moonga, Baljit S.; Zaidi, Mone

2006-01-01

CD38 has multiple roles in biology, including T lymphocyte signaling, neutrophil migration, neurotransmission, cell proliferation, apoptosis, and bone remodeling. To study the transcriptional control of the CD38 gene, we cloned a putative 1.8 kb promoter fragment from a rabbit genomic DNA library. Primer extension analysis indicated two transcription start sites consistent with the absence of a TATA box. Sequence analysis revealed several AP-1, AP-4, myo-D, GATA, and SP-1 sequences. MC3T3.E1 (osteoblast) or RAW-C3 (osteoclast precursor macrophage) cells were then transfected with the CD38 promoter or its deletion fragments ligated to the luciferase reporter gene. Except for the shortest 41 bp fragment, all fragments showed significant luciferase activity. There was a marked stimulation of basal activity in the 93 bp fragment that contained a GC box and SP-1 site. Furthermore, there were significant differences in the activity of the fragments in MC3T3.E1 and RAW-C3 cells. Intracellular Ca 2+ elevations by ionomycin (10 μM) in MC3T3.E1 cells inhibited promoter activity, except in the short 41 bp. In contrast, cAMP elevation by exposure to forskolin (100 μM) inhibited activation of all fragments, except the 0.6 and 1.2 kb fragments. Finally, TNF-α stimulated promoter activity in RAW-C3 cells transfected with the 93 bp and 1.0 kb fragments, consistent with the stimulation of CD38 mRNA by TNF-α. Physiologically, therefore, modulation of the expression of the NAD + -sensing enzyme, CD38, by Ca 2+ , cAMP, and cytokines, such as TNF-α may contribute to coupling the intense metabolic activity of osteoclasts and osteoblasts to their respective bone-resorbing and bone-forming functions

Suppression of cadmium-induced JNK/p38 activation and HSP70 family gene expression by LL-Z1640-2 in NIH3T3 cells

International Nuclear Information System (INIS)

Sugisawa, Nobusuke; Matsuoka, Masato; Okuno, Takeo; Igisu, Hideki

2004-01-01

When NIH3T3 cells were exposed to CdCl 2 , the three major mitogen-activated protein kinases (MAPKs), extracellular signal-regulated protein kinase (ERK), c-Jun NH 2 -terminal kinase (JNK), and p38, were phosphorylated in a time (1-9 h)- and dose (1-20 μM)-dependent manner. Treatment with a macrocyclic nonaketide compound, LL-Z1640-2 (10-100 ng/ml), suppressed the phosphorylation of MAPKs without affecting the total protein level in cells exposed to 10 μM CdCl 2 for 6 h. CdCl 2 -induced phosphorylation of c-Jun on Ser63 and that on Ser73, and resultant accumulation of total c-Jun protein were also suppressed by LL-Z1640-2 treatment. The in vitro kinase assays also showed significant inhibitory effects of LL-Z1640-2 (at 10 or 25 ng/ml) on JNK and p38 but less markedly. In contrast to JNK and p38, ERK activity was inhibited moderately only at 50 or 100 ng/ml LL-Z1640-2. On the other hand, other JNK inhibitors, SP600125 and L-JNKI1, failed to suppress CdCl 2 -induced activation of the JNK pathway. Among the mouse stress response genes upregulated in response to CdCl 2 exposure, the expressions of hsp68 (encoding for heat shock 70 kDa protein 1; Hsp70-1) and grp78 (encoding for 78 kDa glucose-regulated protein; Grp78) genes were suppressed by treatment with 25 ng/ml LL-Z1640-2. Thus, LL-Z1640-2 could suppress CdCl 2 -induced activation of JNK/p38 pathways and expression of HSP70 family genes in NIH3T3 cells. LL-Z1640-2 seems to be useful to analyze functions of toxic metal-induced JNK/p38 activation

Preparation and evaluation of a coumarin library towards the inhibitory activity of the enzyme gGAPDH from Trypanosoma cruzi

Energy Technology Data Exchange (ETDEWEB)

Alvim Junior, Joel; Dias, Ricardo L.A.; Correa, Arlene G. [Universidade Federal de Sao Carlos, SP (Brazil). Dept. de Quimica]. E-mail: agcorrea@power.ufscar.br; Castilho, Marcelo S.; Oliva, Glaucius [Sao Paulo Univ., Sao Carlos, SP (Brazil). Inst. de Fisica

2005-07-15

Chagas' disease, caused by Trypanosoma cruzi, is endemic in 15 countries in Latin America. In this work a library of 38 coumarins was prepared in solution phase and evaluated against T. cruzi glycolytic enzyme glyceraldehyde-3-phosphate-dehydrogenase (gGAPDH). The synthetic route was based on the Knoevenagel condensation of different 2-hydroxybenzaldehydes with Meldrum's acid or diethyl malonate, followed by O-alkylation and/or transesterification reactions. Among the prepared coumarins, the best values obtained to inhibit 50% of the enzymatic activity range from 80 to 130 {mu}M. (author)

Preparation and evaluation of a coumarin library towards the inhibitory activity of the enzyme gGAPDH from Trypanosoma cruzi

International Nuclear Information System (INIS)

Alvim Junior, Joel; Dias, Ricardo L.A.; Correa, Arlene G.; Castilho, Marcelo S.; Oliva, Glaucius

2005-01-01

Chagas' disease, caused by Trypanosoma cruzi, is endemic in 15 countries in Latin America. In this work a library of 38 coumarins was prepared in solution phase and evaluated against T. cruzi glycolytic enzyme glyceraldehyde-3-phosphate-dehydrogenase (gGAPDH). The synthetic route was based on the Knoevenagel condensation of different 2-hydroxybenzaldehydes with Meldrum's acid or diethyl malonate, followed by O-alkylation and/or transesterification reactions. Among the prepared coumarins, the best values obtained to inhibit 50% of the enzymatic activity range from 80 to 130 μM. (author)

P38 mitogen-activated protein kinase (p38 MAPK) overexpression in clinical staging of nasopharyngeal carcinoma

Science.gov (United States)

Farhat; Asnir, R. A.; Yudhistira, A.; Daulay, E. R.; Muzakkir, M. M.; Yulius, S.

2018-03-01

Molecular biological research on nasopharyngeal carcinoma has been widely practiced, such as VEGF, EGFR, COX-2 expression and so on. MAPK plays a role in cell growth such as proliferation, differentiation, and apoptosis, primarily contributing to gene expression, where p38 MAPK pathway mostly associate with anti-apoptosis and cause cell transformation. The aim of this study is to determine the expression of p38 MAPK in clinical stage of nasopharyngeal carcinoma so that the result can be helpful in prognosis and adjunctive therapy in nasopharyngeal carcinoma. The research design is descriptive. It was done in THT- KL Department of FK USU/RSUP Haji Adam Malik, Medan and Pathology Anatomical Department of FK USU. The study was conducted from December 2011 to May 2012. The Samples are all patients who diagnosed with nasopharyngeal carcinoma in oncology division of Otorhinolaryngology Department. p38 MAPK overexpression was found in 21 samples (70%) from 30 nasopharyngeal carcinoma samples. The elevated of p38 MAPK expression most found on T4 by eight samples (38.1%), N3 lymph node group by nine samples (42.9%), stage IV of clinical staging is as many as 15 samples (71.4%). p38 MAPK most expressed in stage IV clinical staging of patients with nasopharyngeal carcinoma.

38 CFR 36.4227 - Advertising and Solicitation Requirements.

Science.gov (United States)

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Advertising and Solicitation Requirements. 36.4227 Section 36.4227 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF... Lots, Including Site Preparation General Provisions § 36.4227 Advertising and Solicitation Requirements...

75 FR 56653 - Suspension of Preparation of Environmental Impact Statement for the George Bush Intercontinental...

Science.gov (United States)

2010-09-16

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Suspension of Preparation of... Aviation Administration (FAA), Department of Transportation (DOT). ACTION: Notice suspending preparation of..., potential changes to aircraft fleet mix, and the need to update the existing terminal concept as reasons...

Comparison of sea surface flux measured by instrumented aircraft and ship during SOFIA and SEMAPHORE experiments

Science.gov (United States)

Durand, Pierre; Dupuis, HéLèNe; Lambert, Dominique; BéNech, Bruno; Druilhet, Aimé; Katsaros, Kristina; Taylor, Peter K.; Weill, Alain

1998-10-01

Two major campaigns (Surface of the Oceans, Fluxes and Interactions with the Atmosphere (SOFIA) and Structure des Echanges Mer-Atmosphère, Propriétés des Hétérogénéités Océaniques: Recherche Expérimentale (SEMAPHORE)) devoted to the study of ocean-atmosphere interaction were conducted in 1992 and 1993, respectively, in the Azores region. Among the various platforms deployed, instrumented aircraft and ship allowed the measurement of the turbulent flux of sensible heat, latent heat, and momentum. From coordinated missions we can evaluate the sea surface fluxes from (1) bulk relations and mean measurements performed aboard the ship in the atmospheric surface layer and (2) turbulence measurements aboard aircraft, which allowed the flux profiles to be estimated through the whole atmospheric boundary layer and therefore to be extrapolated toward the sea surface level. Continuous ship fluxes were calculated with bulk coefficients deduced from inertial-dissipation measurements in the same experiments, whereas aircraft fluxes were calculated with eddy-correlation technique. We present a comparison between these two estimations. Although momentum flux agrees quite well, aircraft estimations of sensible and latent heat flux are lower than those of the ship. This result is surprising, since aircraft momentum flux estimates are often considered as much less accurate than scalar flux estimates. The various sources of errors on the aircraft and ship flux estimates are discussed. For sensible and latent heat flux, random errors on aircraft estimates, as well as variability of ship flux estimates, are lower than the discrepancy between the two platforms, whereas the momentum flux estimates cannot be considered as significantly different. Furthermore, the consequence of the high-pass filtering of the aircraft signals on the flux values is analyzed; it is weak at the lowest altitudes flown and cannot therefore explain the discrepancies between the two platforms but becomes

COMPARATIVE ANALYSIS OF TRANSPORT AIRCRAFT, BACKROUND FOR SHORT/ MEDIUM COURIER TRANSPORT AIRCRAFT PROCUREMENT

Directory of Open Access Journals (Sweden)

Matei POPA

2010-03-01

Full Text Available In accordance with Air Force requirements, the comparative analysis of short/medium transport aircraft comes to sustain procurement decision of short/medium transport aircraft. This paper presents, in short, the principles and the results of the comparative analysis for short/medium military transport aircraft.

Role of IL-38 and Its Related Cytokines in Inflammation

Directory of Open Access Journals (Sweden)

Xianli Yuan

2015-01-01

Full Text Available Interleukin- (IL- 38 is a recently discovered cytokine and is the tenth member of the IL-1 cytokine family. IL-38 shares structural features with IL-1 receptor antagonist (IL-1Ra and IL-36Ra. IL-36R is the specific receptor of IL-38, a partial receptor antagonist of IL-36. IL-38 inhibits the production of T-cell cytokines IL-17 and IL-22. IL-38 also inhibits the production of IL-8 induced by IL-36γ, thus inhibiting inflammatory responses. IL-38-related cytokines, including IL-1Ra and IL-36Ra, are involved in the regulation of inflammation and immune responses. The study of IL-38 and IL-38-related cytokines might provide new insights for developing anti-inflammatory treatments in the near future.

SOLAR AIRCRAFT DESIGN

OpenAIRE

RAHMATI, Sadegh; GHASED, Amir

2015-01-01

Abstract. Generally domain Aircraft uses conventional fuel. These fuel having limited life, high cost and pollutant. Also nowadays price of petrol and other fuels are going to be higher, because of scarcity of those fuels. So there is great demand of use of non-exhaustible unlimited source of energy like solar energy. Solar aircraft is one of the ways to utilize solar energy. Solar aircraft uses solar panel to collect the solar radiation for immediate use but it also store the remaining part ...

Yes!: Rejoinder to "Isn't It Time We Did Something about the Lack of Teaching Preparation in Business Doctoral Programs?"

Science.gov (United States)

Rousseau, Denise M.

2016-01-01

In this rejoinder to, "Isn't It Time We Did Something about the Lack of Teaching Preparation in Business Doctoral Programs?" (Marx, Garcia, Butterfield, Kappen, and Baldwin 2015), the author responds in agreement to the question raised regarding the lack of teaching preparation in business schools. This commentary offers suggestions to…

Aircraft operations management manual

Science.gov (United States)

1992-01-01

The NASA aircraft operations program is a multifaceted, highly diverse entity that directly supports the agency mission in aeronautical research and development, space science and applications, space flight, astronaut readiness training, and related activities through research and development, program support, and mission management aircraft operations flights. Users of the program are interagency, inter-government, international, and the business community. This manual provides guidelines to establish policy for the management of NASA aircraft resources, aircraft operations, and related matters. This policy is an integral part of and must be followed when establishing field installation policy and procedures covering the management of NASA aircraft operations. Each operating location will develop appropriate local procedures that conform with the requirements of this handbook. This manual should be used in conjunction with other governing instructions, handbooks, and manuals.

Conceptual design of high speed supersonic aircraft: A brief review on SR-71 (Blackbird) aircraft

Science.gov (United States)

Xue, Hui; Khawaja, H.; Moatamedi, M.

2014-12-01

The paper presents the conceptual design of high-speed supersonic aircraft. The study focuses on SR-71 (Blackbird) aircraft. The input to the conceptual design is a mission profile. Mission profile is a flight profile of the aircraft defined by the customer. This paper gives the SR-71 aircraft mission profile specified by US air force. Mission profile helps in defining the attributes the aircraft such as wing profile, vertical tail configuration, propulsion system, etc. Wing profile and vertical tail configurations have direct impact on lift, drag, stability, performance and maneuverability of the aircraft. A propulsion system directly influences the performance of the aircraft. By combining the wing profile and the propulsion system, two important parameters, known as wing loading and thrust to weight ratio can be calculated. In this work, conceptual design procedure given by D. P. Raymer (AIAA Educational Series) is applied to calculate wing loading and thrust to weight ratio. The calculated values are compared against the actual values of the SR-71 aircraft. Results indicates that the values are in agreement with the trend of developments in aviation.

Individual aircraft life monitoring: An engineering approach for fatigue damage evaluation

Directory of Open Access Journals (Sweden)

Rui JIAO

2018-04-01

Full Text Available Individual aircraft life monitoring is required to ensure safety and economy of aircraft structure, and fatigue damage evaluation based on collected operational data of aircraft is an integral part of it. To improve the accuracy and facilitate the application, this paper proposes an engineering approach to evaluate fatigue damage and predict fatigue life for critical structures in fatigue monitoring. In this approach, traditional nominal stress method is applied to back calculate the S-N curve parameters of the realistic structure details based on full-scale fatigue test data. Then the S-N curve and Miner’s rule are adopted in damage estimation and fatigue life analysis for critical locations under individual load spectra. The relationship between relative small crack length and fatigue life can also be predicted with this approach. Specimens of 7B04-T74 aluminum alloy and TA15M titanium alloy are fatigue tested under two types of load spectra, and there is a good agreement between the experimental results and analysis results. Furthermore, the issue concerning scatter factor in individual aircraft damage estimation is also discussed. Keywords: Fatigue damage, Fatigue monitoring, Fatigue test, Scatter factor, S-N curve

Immunological quality and performance of tumor vessel-targeting CAR-T cells prepared by mRNA-EP for clinical research.

Science.gov (United States)

Inoo, Kanako; Inagaki, Ryo; Fujiwara, Kento; Sasawatari, Shigemi; Kamigaki, Takashi; Nakagawa, Shinsaku; Okada, Naoki

2016-01-01

We previously reported that tumor vessel-redirected T cells, which were genetically engineered with chimeric antigen receptor (CAR) specific for vascular endothelial growth factor receptor 2 (VEGFR2), demonstrated significant antitumor effects in various murine solid tumor models. In the present study, we prepared anti-VEGFR2 CAR-T cells by CAR-coding mRNA electroporation (mRNA-EP) and analyzed their immunological characteristics and functions for use in clinical research. The expression of anti-VEGFR2 CAR on murine and human T cells was detected with approximately 100% efficiency for a few days, after peaking 6-12 hours after mRNA-EP. Triple transfer of murine anti-VEGFR2 CAR-T cells into B16BL6 tumor-bearing mice demonstrated an antitumor effect comparable to that for the single transfer of CAR-T cells engineered with retroviral vector. The mRNA-EP did not cause any damage or defects to human T-cell characteristics, as determined by viability, growth, and phenotypic parameters. Additionally, two kinds of human anti-VEGFR2 CAR-T cells, which expressed different CAR construction, differentiated to effector phase with cytokine secretion and cytotoxic activity in antigen-specific manner. These results indicate that our anti-VEGFR2 CAR-T cells prepared by mRNA-EP have the potential in terms of quality and performance to offer the prospect of safety and efficacy in clinical research as cellular medicine.

Immunological quality and performance of tumor vessel-targeting CAR-T cells prepared by mRNA-EP for clinical research

Directory of Open Access Journals (Sweden)

Kanako Inoo

2016-01-01

Full Text Available We previously reported that tumor vessel-redirected T cells, which were genetically engineered with chimeric antigen receptor (CAR specific for vascular endothelial growth factor receptor 2 (VEGFR2, demonstrated significant antitumor effects in various murine solid tumor models. In the present study, we prepared anti-VEGFR2 CAR-T cells by CAR-coding mRNA electroporation (mRNA-EP and analyzed their immunological characteristics and functions for use in clinical research. The expression of anti-VEGFR2 CAR on murine and human T cells was detected with approximately 100% efficiency for a few days, after peaking 6–12 hours after mRNA-EP. Triple transfer of murine anti-VEGFR2 CAR-T cells into B16BL6 tumor-bearing mice demonstrated an antitumor effect comparable to that for the single transfer of CAR-T cells engineered with retroviral vector. The mRNA-EP did not cause any damage or defects to human T-cell characteristics, as determined by viability, growth, and phenotypic parameters. Additionally, two kinds of human anti-VEGFR2 CAR-T cells, which expressed different CAR construction, differentiated to effector phase with cytokine secretion and cytotoxic activity in antigen-specific manner. These results indicate that our anti-VEGFR2 CAR-T cells prepared by mRNA-EP have the potential in terms of quality and performance to offer the prospect of safety and efficacy in clinical research as cellular medicine.

Accurate Measurements of Aircraft Engine Soot Emissions Using a CAPS PMssa Monitor

Science.gov (United States)

Onasch, Timothy; Thompson, Kevin; Renbaum-Wolff, Lindsay; Smallwood, Greg; Make-Lye, Richard; Freedman, Andrew

2016-04-01

We present results of aircraft engine soot emissions measurements during the VARIAnT2 campaign using CAPS PMssa monitors. VARIAnT2, an aircraft engine non-volatile particulate matter (nvPM) emissions field campaign, was focused on understanding the variability in nvPM mass measurements using different measurement techniques and accounting for possible nvPM sampling system losses. The CAPS PMssa monitor accurately measures both the optical extinction and scattering (and thus single scattering albedo and absorption) of an extracted sample using the same sample volume for both measurements with a time resolution of 1 second and sensitivity of better than 1 Mm-1. Absorption is obtained by subtracting the scattering signal from the total extinction. Given that the single scattering albedo of the particulates emitted from the aircraft engine measured at both 630 and 660 nm was on the order of 0.1, any inaccuracy in the scattering measurement has little impact on the accuracy of the ddetermined absorption coefficient. The absorption is converted into nvPM mass using a documented Mass Absorption Coefficient (MAC). Results of soot emission indices (mass soot emitted per mass of fuel consumed) for a turbojet engine as a function of engine power will be presented and compared to results obtained using an EC/OC monitor.

Phosphorylation of the Grb2- and phosphatidylinositol 3-kinase p85-binding p36/38 by Syk in Lck-negative T cells.

Science.gov (United States)

von Willebrand, M; Williams, S; Tailor, P; Mustelin, T

1998-06-01

Activation of the mitogen-activated protein kinase (MAPK) pathway by the T-cell antigen receptor (TCR) in T cells involves a positive role for phosphatidylinositol 3-kinase (PI3K) activity. We recently reported that over-expression of the Syk protein tyrosine kinase in the Lck-negative JCaM1 cells enabled the TCR to induce a normal activation of the Erk2 MAPK and enhanced transcription of a reporter gene driven by the nuclear factor of activated T cells and AP-1. Because this system allows us to analyse the targets for Syk in receptor-mediated signalling, we examined the role of PI3K in signalling events between the TCR-regulated Syk and the downstream activation of Erk2. We report that inhibition of PI3K by wortmannin or an inhibitory p85 construct, p85deltaiSH2, reduced the TCR-induced Syk-dependent activation of Erk2, as well as the appearance of phospho-Erk and phospho-Mek. At the same time, expression of Syk resulted in the activation-dependent phosphorylation of three proteins that bound to the src homology 2 (SH2) domains of PI3K p85. The strongest of these bands had an apparent molecular mass of 36-38 kDa on SDS gels, and it was quantitatively removed from the lysates by adsorption to a fusion protein containing the SH2 domain of Grb2. The appearance of this band was Syk dependent, and it was seen only upon triggering of the TCR complex. Thus, p36/38 was phosphorylated by Syk or a Syk-regulated kinase, and this protein may provide a link to the recruitment and activation of PI3K, as well as to the Ras-MAPK pathway, in TCR-triggered T cells.

Factors affecting ozone removal rates in a simulated aircraft cabin environment

DEFF Research Database (Denmark)

Tamas, Gyöngyi; Weschler, Charles J.; Bako-Biro, Zsolt

2006-01-01

of people, soiled T-shirts, aircraft seats and a used HEPA filter, we have been able in the course of 24 experiments to isolate the contributions of these and other factors to the removal of ozone from the cabin air. In the case of this simulated aircraft, people were responsible for almost 60% of the ozone...... present, the measured ratio of ozone's concentration in the cabin versus that outside the cabin was 0.15-0.21, smaller than levels reported in the literature. The results reinforce the conclusion that the optimal way to reduce people's exposure to both ozone and ozone oxidation products is to efficiently...

Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways

Science.gov (United States)

Yang, Tingfang; Yao, Shuluan; Zhang, Xianfeng; Guo, Yan

2016-01-01

T-cell acute lymphoblastic leukemia (T-ALL) as a prevalent hematologic malignancy is one of the most common malignant tumors worldwide in children. Andrographolide (Andro), the major active component from Andrographis paniculata, has been shown to possess antitumor activities in several types of cancer cells. However, whether Andro would inhibit T-ALL cell growth remains unclear. In this study, we investigated the cytotoxic effect of Andro on human T-ALL Jurkat cells and explored the mechanisms of cell death. Cell apoptosis was assayed by flow cytometry, and the signaling transduction for Andro was analyzed by Western blotting. The results indicated 10 μg/mL Andro could significantly induce Jurkat cells’ apoptosis, depending on the inhibition of PI3K/AKT pathway. Moreover, Andro-induced apoptosis is enhanced by AKT-selective inhibitor LY294002. ERK- or JNK-selective inhibitors PD98059 and SP600125 had no effect on Andro-induced apoptosis. In addition, p38 inhibitor SB203580 could reverse Andro-induced apoptosis in Jurkat cells. We also found that the protein expression of p-p53 and p-p38 were increased after Andro treatments. The result of an in vivo study also demonstrated Andro’s dose-dependent inhibition in subcutaneous Jurkat xenografts. In conclusion, our findings explained a novel mechanism of drug action by Andro in Jurkat cells and suggested that Andro might be developed into a new candidate therapy for T-ALL patients in the coming days. PMID:27114702

Solar thermal aircraft

Science.gov (United States)

Bennett, Charles L.

2007-09-18

A solar thermal powered aircraft powered by heat energy from the sun. A heat engine, such as a Stirling engine, is carried by the aircraft body for producing power for a propulsion mechanism, such as a propeller. The heat engine has a thermal battery in thermal contact with it so that heat is supplied from the thermal battery. A solar concentrator, such as reflective parabolic trough, is movably connected to an optically transparent section of the aircraft body for receiving and concentrating solar energy from within the aircraft. Concentrated solar energy is collected by a heat collection and transport conduit, and heat transported to the thermal battery. A solar tracker includes a heliostat for determining optimal alignment with the sun, and a drive motor actuating the solar concentrator into optimal alignment with the sun based on a determination by the heliostat.

T2-prepared velocity selective labelling

DEFF Research Database (Denmark)

Alderliesten, Thomas; De Vis, Jill B; Lemmers, Petra M A

2016-01-01

2-BIOS correlated with SO2-NIRS (R(2)=0.41, p=0.002) and SvO2-T2-TRIR (R(2)=0.87, p=0.002). In addition, SO2-NIRS correlated with SvO2-T2-TRIR (R(2)=0.85, p=0.003) Frontal cerebral blood flow correlated with SO2-T2-BIOS (R(2)=0.21, p=0.04), but was not significant in relation to SO2-NIRS. DISCUSSION...

Factors associated with pilot fatality in work-related aircraft crashes, Alaska, 1990-1999.

Science.gov (United States)

Bensyl, D M; Moran, K; Conway, G A

2001-12-01

Work-related aircraft crashes are the leading cause of occupational fatality in Alaska, with civilian pilots having the highest fatality rate (410/100,000/year). To identify factors affecting survivability, the authors examined work-related aircraft crashes that occurred in Alaska in the 1990s (1990-1999), comparing crashes with pilot fatalities to crashes in which the pilot survived. Using data from National Transportation Safety Board reports, the authors carried out logistic regression analysis with the following variables: age, flight experience, use of a shoulder restraint, weather conditions (visual flight vs. instrument flight), light conditions (daylight vs. darkness), type of aircraft (airplane vs. helicopter), postcrash fire, crash location (airport vs. elsewhere), and state of residence. In the main-effects model, significant associations were found between fatality and postcrash fire (adjusted odds ratio (AOR) = 6.43, 95% confidence interval (CI): 2.38, 17.37), poor weather (AOR = 4.11, 95% CI: 2.15, 7.87), and non-Alaska resident status (AOR = 2.10, 95% CI: 1.05, 4.20). Protective effects were seen for shoulder restraint use (AOR = 0.40, 95% CI: 0.21, 0.77) and daylight versus darkness (AOR = 0.50, 95% CI: 0.25, 0.99). The finding that state of residence was associated with survivability offers new information on pilot survivability in work-related aircraft crashes in Alaska. These results may be useful in targeting safety interventions for pilots who fly occupationally in Alaska or in similar environments.

In vivo evaluation of titanium-prepared platelet-rich fibrin (T-PRF): a new platelet concentrate.

Science.gov (United States)

Tunalı, Mustafa; Özdemir, Hakan; Küçükodacı, Zafer; Akman, Serhan; Fıratlı, Erhan

2013-07-01

We have developed a new, titanium-prepared, platelet-rich fibrin (T-PRF) together with the protocol for forming it, which is based on the hypothesis that titanium tubes may be more effective at activating platelets than the glass tubes used by Chouckroun in his platelet-rich fibrin (PRF) method. The aim of this study was to find a suitable animal model in which to evaluate the method and to investigate the efficacy of T-PRF for wound healing. Blood samples from 6 rabbits were used to confirm the protocol for formation of T-PRF. We evaluated T-PRF or T-PRF-like clots morphologically using scanning electron microscopy (EM). Blood samples from 5 rabbits were used to develop an experiment in which to evaluate the effects of T-PRF on wound healing. The mucoperiosteal flaps were filled with autologous T-PRF membranes from the vestibule in the anterior mandibular regions. Samples collected from the surgical sites were stained with haematoxylin and eosin. We found a mature fibrin network in T-PRF clots that had been centrifuged for 15 min at 3500 rpm and, 15 days after placement of the membrane, we found newly-forming connective tissue and islets of bony tissue in the T-PRF membrane. These results show that T-PRF could induce the formation of new bone with new connective tissue in a rabbit model of wound healing within 30 days of treatment. Published by Elsevier Ltd.

Long Range Aircraft Trajectory Prediction

OpenAIRE

Magister, Tone

2009-01-01

The subject of the paper is the improvement of the aircraft future trajectory prediction accuracy for long-range airborne separation assurance. The strategic planning of safe aircraft flights and effective conflict avoidance tactics demand timely and accurate conflict detection based upon future four–dimensional airborne traffic situation prediction which is as accurate as each aircraft flight trajectory prediction. The improved kinematics model of aircraft relative flight considering flight ...

Adapting existing training standards for unmanned aircraft: finding ways to train staff for unmanned aircraft operations

CSIR Research Space (South Africa)

Burger, CR

2011-09-01

Full Text Available - unmanned aircraft; pilot training. I. INTRODUCTION Unmanned aircraft offer flexibility not found in manned aircraft. They can be made smaller and cheaper to operate. They offer payload advantages relative to small manned aircraft. They can also perform... certificate to non-state users. To facilitate useful operations by UAs, future operations must be subject to no more than routine notification (e.g. an ATC flight plan), just like manned aircraft already are. Before such operations can be established, some...

Bayesian Computational Sensor Networks for Aircraft Structural Health Monitoring

Science.gov (United States)

2016-02-02

Virginia 22203 Air Force Research Laboratory Air Force Materiel Command 1 Final Performance Report: AFOSR T.C. Henderson , V.J. Mathews, and D...AFRL-AFOSR-VA-TR-2016-0094 Bayesian Computational Sensor Networks for Aircraft Structural Health Monitoring. Thomas Henderson UNIVERSITY OF UTAH SALT...The people who worked on this project include: Thomas C. Henderson , John Mathews, Jingru Zhou, Daimei Zhij, Ahmad Zoubi, Sabita Nahata, Dan Adams

Hybrid metaheuristic optimization algorithm for strategic planning of {4D} aircraft trajectories at the continent scale

OpenAIRE

Chaimatanan , Supatcha; Delahaye , Daniel; Mongeau , Marcel

2014-01-01

International audience; Global air-traffic demand is continuously increasing. To handle such a tremendous traffic volume while maintaining at least the same level of safety, a more efficient strategic trajectory planning is necessary. In this work, we present a strategic trajectory planning methodology which aims to minimize interaction between aircraft at the European-continent scale. In addition, we propose a preliminary study that takes into account uncertainties of aircraft positions in t...

40 CFR 87.6 - Aircraft safety.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Aircraft safety. 87.6 Section 87.6... POLLUTION FROM AIRCRAFT AND AIRCRAFT ENGINES General Provisions § 87.6 Aircraft safety. The provisions of... met within the specified time without creating a safety hazard. ...

Prediction of transmission loss through an aircraft sidewall using statistical energy analysis

Science.gov (United States)

Ming, Ruisen; Sun, Jincai

1989-06-01

The transmission loss of randomly incident sound through an aircraft sidewall is investigated using statistical energy analysis. Formulas are also obtained for the simple calculation of sound transmission loss through single- and double-leaf panels. Both resonant and nonresonant sound transmissions can be easily calculated using the formulas. The formulas are used to predict sound transmission losses through a Y-7 propeller airplane panel. The panel measures 2.56 m x 1.38 m and has two windows. The agreement between predicted and measured values through most of the frequency ranges tested is quite good.

Examining the Relationship Between Passenger Airline Aircraft Maintenance Outsourcing and Aircraft Safety

Science.gov (United States)

Monaghan, Kari L.

The problem addressed was the concern for aircraft safety rates as they relate to the rate of maintenance outsourcing. Data gathered from 14 passenger airlines: AirTran, Alaska, America West, American, Continental, Delta, Frontier, Hawaiian, JetBlue, Midwest, Northwest, Southwest, United, and USAir covered the years 1996 through 2008. A quantitative correlational design, utilizing Pearson's correlation coefficient, and the coefficient of determination were used in the present study to measure the correlation between variables. Elements of passenger airline aircraft maintenance outsourcing and aircraft accidents, incidents, and pilot deviations within domestic passenger airline operations were analyzed, examined, and evaluated. Rates of maintenance outsourcing were analyzed to determine the association with accident, incident, and pilot deviation rates. Maintenance outsourcing rates used in the evaluation were the yearly dollar expenditure of passenger airlines for aircraft maintenance outsourcing as they relate to the total airline aircraft maintenance expenditures. Aircraft accident, incident, and pilot deviation rates used in the evaluation were the yearly number of accidents, incidents, and pilot deviations per miles flown. The Pearson r-values were calculated to measure the linear relationship strength between the variables. There were no statistically significant correlation findings for accidents, r(174)=0.065, p=0.393, and incidents, r(174)=0.020, p=0.793. However, there was a statistically significant correlation for pilot deviation rates, r(174)=0.204, p=0.007 thus indicating a statistically significant correlation between maintenance outsourcing rates and pilot deviation rates. The calculated R square value of 0.042 represents the variance that can be accounted for in aircraft pilot deviation rates by examining the variance in aircraft maintenance outsourcing rates; accordingly, 95.8% of the variance is unexplained. Suggestions for future research include

System for indicating fuel-efficient aircraft altitude

Science.gov (United States)

Gary, B. L. (Inventor)

1984-01-01

A method and apparatus are provided for indicating the altitude at which an aircraft should fly so the W/d ratio (weight of the aircraft divided by the density of air) more closely approaches the optimum W/d for the aircraft. A passive microwave radiometer on the aircraft is directed at different angles with respect to the horizon to determine the air temperature, and therefore the density of the air, at different altitudes. The weight of the aircraft is known. The altitude of the aircraft is changed to fly the aircraft at an altitude at which is W/d ratio more closely approaches the optimum W/d ratio for that aircraft.

150 Passenger Commercial Aircraft

Science.gov (United States)

Bucovsky, Adrian; Romli, Fairuz I.; Rupp, Jessica

2002-01-01

It has been projected that the need for a short-range mid-sized, aircraft is increasing. The future strategy to decrease long-haul flights will increase the demand for short-haul flights. Since passengers prefer to meet their destinations quickly, airlines will increase the frequency of flights, which will reduce the passenger load on the aircraft. If a point-to-point flight is not possible, passengers will prefer only a one-stop short connecting flight to their final destination. A 150-passenger aircraft is an ideal vehicle for these situations. It is mid-sized aircraft and has a range of 3000 nautical miles. This type of aircraft would market U.S. domestic flights or inter-European flight routes. The objective of the design of the 150-passenger aircraft is to minimize fuel consumption. The configuration of the aircraft must be optimized. This aircraft must meet CO2 and NOx emissions standards with minimal acquisition price and operating costs. This report contains all the work that has been performed for the completion of the design of a 150 passenger commercial aircraft. The methodology used is the Technology Identification, Evaluation, and Selection (TIES) developed at Georgia Tech Aerospace Systems Design laboratory (ASDL). This is an eight-step conceptual design process to evaluate the probability of meeting the design constraints. This methodology also allows for the evaluation of new technologies to be implemented into the design. The TIES process begins with defining the problem with a need established and a market targeted. With the customer requirements set and the target values established, a baseline concept is created. Next, the design space is explored to determine the feasibility and viability of the baseline aircraft configuration. If the design is neither feasible nor viable, new technologies can be implemented to open up the feasible design space and allow for a plausible solution. After the new technologies are identified, they must be evaluated

X-38 Drop Model: Landing Sequence Collage from Cessna Drop Test

Science.gov (United States)

1995-01-01

This sequence of photographs shows a 4-foot-long model of NASA's X-38 gliding to earth after being dropped from a Cessna aircraft in late 1995. The model was used to test the ram-air parafoil landing system, which could allow for accurate and controlled landings of an emergency Crew Return Vehicle spacecraft returning to earth. The X-38 Crew Return Vehicle (CRV) research project is designed to develop the technology for a prototype emergency crew return vehicle, or lifeboat, for the International Space Station. The project is also intended to develop a crew return vehicle design that could be modified for other uses, such as a joint U.S. and international human spacecraft that could be launched on the French Ariane-5 Booster. The X-38 project is using available technology and off-the-shelf equipment to significantly decrease development costs. Original estimates to develop a capsule-type crew return vehicle were estimated at more than $2 billion. X-38 project officials have estimated that development costs for the X-38 concept will be approximately one quarter of the original estimate. Off-the-shelf technology is not necessarily 'old' technology. Many of the technologies being used in the X-38 project have never before been applied to a human-flight spacecraft. For example, the X-38 flight computer is commercial equipment currently used in aircraft and the flight software operating system is a commercial system already in use in many aerospace applications. The video equipment for the X-38 is existing equipment, some of which has already flown on the space shuttle for previous NASA experiments. The X-38's primary navigational equipment, the Inertial Navigation System/Global Positioning System, is a unit already in use on Navy fighters. The X-38 electromechanical actuators come from previous joint NASA, U.S. Air Force, and U.S. Navy research and development projects. Finally, an existing special coating developed by NASA will be used on the X-38 thermal tiles to

Fettered aircraft for using wind energy

Energy Technology Data Exchange (ETDEWEB)

Hoeppner, H.; Horvath, E.; Ulrich, S.

1980-08-28

The invention concerns an aircraft tethered by cables, whose balloon-shaped central body produces static and aerodynamic upthrust and which carries turbines, which are used to convert wind energy and to drive the aircraft. The purpose of the invention is to provide an aircraft, which will keep wind energy plant at the optimum height. A new type of aircraft is used to solve the problem, which, according to the invention, combines static upthrust, the production of aerodynamic upthrust, wind energy conversion, energy transport and forward drive in a technically integrated aircraft. If the use of windpower is interrupted, then if necessary the drive together with a remote control system provides controlled free flight of the aircraft. One variant of the object of the invention consists of a central, balloon-shaped body for upthrust, in which there are wind turbines driving electrical generators. According to the invention the motors required to start the wind turbines are of such dimensions that they will drive the turbines in free flight of the aircraft and thus provide forward drive of the aircraft. A power generating unit, consisting of an internal combustion engine and the starter motors switched over to generator operation is used to provide house service supplies for control and regulation of the aircraft.

Multirole cargo aircraft options and configurations. [economic analysis

Science.gov (United States)

Conner, D. W.; Vaughan, J. C., III

1979-01-01

A future requirements and advanced market evaluation study indicates derivatives of current wide-body aircraft, using 1980 advanced technology, would be economically attractive through 2008, but new dedicated airfreighters incorporating 1990 technology, would offer little or no economic incentive. They would be economically attractive for all payload sizes, however, if RD and T costs could be shared in a joint civil/military arrangement. For the 1994-2008 cargo market, option studies indicate Mach 0.7 propfans would be economically attractive in trip cost, aircraft price and airline ROI. Spanloaders would have an even lower price and higher ROI but would have a relatively high trip cost because of aerodynamic inefficiencies. Dedicated airfreighters using propfans at Mach 0.8 cruise, laminar flow control, or cryofuels, would not provide any great economic benefits. Air cushion landing gear configurations are identified as an option for avoiding runway constraints on airport requirements and/or operational constraints are noted.

Aircraft Capability Management

Science.gov (United States)

Mumaw, Randy; Feary, Mike

2018-01-01

This presentation presents an overview of work performed at NASA Ames Research Center in 2017. The work concerns the analysis of current aircraft system management displays, and the initial development of an interface for providing information about aircraft system status. The new interface proposes a shift away from current aircraft system alerting interfaces that report the status of physical components, and towards displaying the implications of degradations on mission capability. The proposed interface describes these component failures in terms of operational consequences of aircraft system degradations. The research activity was an effort to examine the utility of different representations of complex systems and operating environments to support real-time decision making of off-nominal situations. A specific focus was to develop representations that provide better integrated information to allow pilots to more easily reason about the operational consequences of the off-nominal situations. The work is also seen as a pathway to autonomy, as information is integrated and understood in a form that automated responses could be developed for the off-nominal situations in the future.

Essentials of aircraft armaments

CERN Document Server

Kaushik, Mrinal

2017-01-01

This book aims to provide a complete exposure about armaments from their design to launch from the combat aircraft. The book details modern ammunition and their tactical roles in warfare. The proposed book discusses aerodynamics, propulsion, structural as well as navigation, control, and guidance of aircraft armament. It also introduces the various types of ammunition developed by different countries and their changing trends. The book imparts knowledge in the field of design, and development of aircraft armaments to aerospace engineers and covers the role of the United Nations in peacekeeping and disarmament. The book will be very useful to researchers, students, and professionals working in design and manufacturing of aircraft armaments. The book will also serve air force and naval aspirants, and those interested in working on defence research and developments organizations. .

38 CFR 36.4223 - Interest rate reduction refinancing loan.

Science.gov (United States)

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Interest rate reduction..., Including Site Preparation General Provisions § 36.4223 Interest rate reduction refinancing loan. (a) A... to reduce the interest rate payable on the Department of Veterans Affairs loan provided the following...

Ground noise measurements during static and flyby operations of the Cessna 02-T turbine powered airplane

Science.gov (United States)

Hilton, D. A.; Henderson, H. R.; Lawton, B. W.

1975-01-01

The field noise measurements on the Cessna 02-T turbine powered propeller aircraft are presented. The objective of the study was to obtain the basic noise characteristics of the aircraft during static ground runs and flyover tests, to identify the sources of the noise, and to correlate the noises with the aircraft operating conditions. The results are presented in the form of a overall noise levels, radiation patterns, and frequency spectra. The noise characteristics of the turbine powered aircraft are compared with those of the reciprocating engine powered aircraft.

T K Umesh

Indian Academy of Sciences (India)

Home; Journals; Pramana – Journal of Physics. T K Umesh. Articles written in Pramana – Journal of Physics. Volume 58 Issue 1 January 2002 pp 31-38 Research Articles. X-ray fluorescence in some rare earth and high elements excited by 661.6 keV -rays · T Yashoda S Krishnaveni Shivalinge Gowda T K Umesh ...

The distribution of IL-13 receptor alpha1 expression on B cells, T cells and monocytes and its regulation by IL-13 and IL-4.

Science.gov (United States)

Graber, P; Gretener, D; Herren, S; Aubry, J P; Elson, G; Poudrier, J; Lecoanet-Henchoz, S; Alouani, S; Losberger, C; Bonnefoy, J Y; Kosco-Vilbois, M H; Gauchat, J F

1998-12-01

To study the expression of IL-13 receptor alpha1 (IL-13Ralpha1), specific monoclonal antibodies (mAb) were generated. Surface expression of the IL-13Ralpha1 on B cells, monocytes and T cells was assessed by flow cytometry using these specific mAb. Among tonsillar B cells, the expression was the highest on the IgD+ CD38- B cell subpopulation which is believed to represent naive B cells. Expression was also detectable on a large fraction of the IgD-CD38- B cells but not on CD38+ B cells. Activation under conditions which promote B cell Ig class switching up-regulated the expression of the receptor. However, the same stimuli had an opposite effect for IL-13Ralpha1 expression levels on monocytes. While IL-13Ralpha1 mRNA was clearly detectable in T cell preparations, no surface expression was detected. However, permeabilization of the T cells showed a clear intracellular expression of the receptor. A soluble form of the receptor was immunoprecipitated from the supernatant of activated peripheral T cells, suggesting that T cell IL-13Ralpha1 might have functions unrelated to the capacity to form a type II IL-4/IL-13R with IL-4Ralpha.

A cost-effective method for Illumina small RNA-Seq library preparation using T4 RNA ligase 1 adenylated adapters

Directory of Open Access Journals (Sweden)

Chen Yun-Ru

2012-09-01

Full Text Available Abstract Background Deep sequencing is a powerful tool for novel small RNA discovery. Illumina small RNA sequencing library preparation requires a pre-adenylated 3’ end adapter containing a 5’,5’-adenyl pyrophosphoryl moiety. In the absence of ATP, this adapter can be ligated to the 3’ hydroxyl group of small RNA, while RNA self-ligation and concatenation are repressed. Pre-adenylated adapters are one of the most essential and costly components required for library preparation, and few are commercially available. Results We demonstrate that DNA oligo with 5’ phosphate and 3’ amine groups can be enzymatically adenylated by T4 RNA ligase 1 to generate customized pre-adenylated adapters. We have constructed and sequenced a small RNA library for tomato (Solanum lycopersicum using the T4 RNA ligase 1 adenylated adapter. Conclusion We provide an efficient and low-cost method for small RNA sequencing library preparation, which takes two days to complete and costs around $20 per library. This protocol has been tested in several plant species for small RNA sequencing including sweet potato, pepper, watermelon, and cowpea, and could be readily applied to any RNA samples.

Hydrogen Storage for Aircraft Applications Overview

Science.gov (United States)

Colozza, Anthony J.; Kohout, Lisa (Technical Monitor)

2002-01-01

Advances in fuel cell technology have brought about their consideration as sources of power for aircraft. This power can be utilized to run aircraft systems or even provide propulsion power. One of the key obstacles to utilizing fuel cells on aircraft is the storage of hydrogen. An overview of the potential methods of hydrogen storage was compiled. This overview identifies various methods of hydrogen storage and points out their advantages and disadvantages relative to aircraft applications. Minimizing weight and volume are the key aspects to storing hydrogen within an aircraft. An analysis was performed to show how changes in certain parameters of a given storage system affect its mass and volume.

Estimation of nuclear power plant aircraft hazards

International Nuclear Information System (INIS)

Gottlieb, P.

1978-01-01

The standard procedures for estimating aircraft risk to nuclear power plants provide a conservative estimate, which is adequate for most sites, which are not close to airports or heavily traveled air corridors. For those sites which are close to facilities handling large numbers of aircraft movements (airports or corridors), a more precise estimate of aircraft impact frequency can be obtained as a function of aircraft size. In many instances the very large commercial aircraft can be shown to have an acceptably small impact frequency, while the very small general aviation aircraft will not produce sufficiently serious impact to impair the safety-related functions. This paper examines the in between aircraft: primarily twin-engine, used for business, pleasure, and air taxi operations. For this group of aircraft the total impact frequency was found to be approximately once in one million years, the threshold above which further consideration of specific safety-related consequences would be required

Aircraft Carrier Exposure Testing of Aircraft Materials

National Research Council Canada - National Science Library

Lee, Eui

2004-01-01

.... Test and control specimens were affixed on exposure racks and installed on aircraft carriers to compare adhesive bonding primers for aluminum and to determine the static property behavior of various...

Cirrus Airframe Parachute System and Odds of a Fatal Accident in Cirrus Aircraft Crashes.

Science.gov (United States)

Alaziz, Mustafa; Stolfi, Adrienne; Olson, Dean M

2017-06-01

General aviation (GA) accidents have continued to demonstrate high fatality rates. Recently, ballistic parachute recovery systems (BPRS) have been introduced as a safety feature in some GA aircraft. This study evaluates the effectiveness and associated factors of the Cirrus Airframe Parachute System (CAPS) at reducing the odds of a fatal accident in Cirrus aircraft crashes. Publicly available Cirrus aircraft crash reports were obtained from the National Transportation Safety Board (NTSB) database for the period of January 1, 2001-December 31, 2016. Accident metrics were evaluated through univariate and multivariate analyses regarding odds of a fatal accident and use of the parachute system. Included in the study were 268 accidents. For CAPS nondeployed accidents, 82 of 211 (38.9%) were fatal as compared to 8 of 57 (14.0%) for CAPS deployed accidents. After controlling for all other factors, the adjusted odds ratio for a fatal accident when CAPS was not deployed was 13.1. The substantial increased odds of a fatal accident when CAPS was not deployed demonstrated the effectiveness of CAPS at providing protection of occupants during an accident. Injuries were shifted from fatal to serious or minor with the use of CAPS and postcrash fires were significantly reduced. These results suggest that BPRS could play a significant role in the next major advance in improving GA accident survival.Alaziz M, Stolfi A, Olson DM. Cirrus Airframe Parachute System and odds of a fatal accident in Cirrus aircraft crashes. Aerosp Med Hum Perform. 2017; 88(6):556-564.

Identification of Aircraft Hazards

International Nuclear Information System (INIS)

K. Ashley

2006-01-01

Aircraft hazards were determined to be potentially applicable to a repository at Yucca Mountain in ''Monitored Geological Repository External Events Hazards Screening Analysis'' (BSC 2005 [DIRS 174235], Section 6.4.1). That determination was conservatively based upon limited knowledge of flight data in the area of concern and upon crash data for aircraft of the type flying near Yucca Mountain. The purpose of this report is to identify specific aircraft hazards that may be applicable to a monitored geologic repository (MGR) at Yucca Mountain, using NUREG-0800, ''Standard Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants'' (NRC 1987 [DIRS 103124], Section 3.5.1.6), as guidance for the inclusion or exclusion of identified aircraft hazards. The intended use of this report is to provide inputs for further screening and analysis of identified aircraft hazards based upon the criteria that apply to Category 1 and Category 2 event sequence analyses as defined in 10 CFR 63.2 [DIRS 176544] (Section 4). The scope of this report includes the evaluation of military, private, and commercial use of airspace in the 100-mile regional setting of the repository at Yucca Mountain with the potential for reducing the regional setting to a more manageable size after consideration of applicable screening criteria (Section 7)

Flight assessment of a large supersonic drone aircraft for research use

Science.gov (United States)

Eckstrom, C. V.; Peele, E. L.

1974-01-01

An assessment is made of the capabilities of the BQM-34E supersonic drone aircraft as a test bed research vehicle. This assessment is made based on a flight conducted for the purpose of obtaining flight test measurements of wing loads at various maneuver flight conditions. Flight plan preparation, flight simulation, and conduct of the flight test are discussed along with a presentation of the test data obtained and an evaluation of how closely the flight test followed the test plan.

14 CFR 49.11 - FAA Aircraft Registry.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false FAA Aircraft Registry. 49.11 Section 49.11... AIRCRAFT TITLES AND SECURITY DOCUMENTS General § 49.11 FAA Aircraft Registry. To be eligible for recording, a conveyance must be mailed to the FAA Aircraft Registry, Department of Transportation, Post Office...

Annoyance by aircraft noise and fear of overflying aircraft in relation to attitudes toward the environment and community

Science.gov (United States)

Loeb, M.; Moran, S. V.

1977-01-01

It has been suggested that expressions of annoyance attributable to aircraft noise may reflect in part fear of aircraft overflights and possible crashes. If this is true, then residents of areas where crashes have occurred should express more annoyance. To test this hypothesis, 50 residents of an Albany, New York area where an aircraft crash producing fatalities recently occurred and 50 residents of a comparable nearby area without such a history, were asked to respond to a 'Quality of Life Questionnaire.' Among the items were some designed to test annoyance by noise and fear of aircraft overflights. It was predicted that those in the crash area would express more fear and would more often identify aircraft as a noise source. These hypotheses were sustained. A near-replication was carried out in Louisville, Kentucky; results were much the same. Analyses indicated that for the crash-area groups, there was associating of aircraft fear and noise annoyance responses; this was true to an apparently lesser extent for non-crash groups. The greater annoyance of crash groups by aircraft community noise apparently does not carry over to situations in which aircraft noise is assessed in the laboratory.

The Aircraft Morphing Program

Science.gov (United States)

Wlezien, R. W.; Horner, G. C.; McGowan, A. R.; Padula, S. L.; Scott, M. A.; Silcox, R. J.; Simpson, J. O.

1998-01-01

In the last decade smart technologies have become enablers that cut across traditional boundaries in materials science and engineering. Here we define smart to mean embedded actuation, sensing, and control logic in a tightly coupled feedback loop. While multiple successes have been achieved in the laboratory, we have yet to see the general applicability of smart devices to real aircraft systems. The NASA Aircraft Morphing program is an attempt to couple research across a wide range of disciplines to integrate smart technologies into high payoff aircraft applications. The program bridges research in seven individual disciplines and combines the effort into activities in three primary program thrusts. System studies are used to assess the highest- payoff program objectives, and specific research activities are defined to address the technologies required for development of smart aircraft systems. In this paper we address the overall program goals and programmatic structure, and discuss the challenges associated with bringing the technologies to fruition.

Smart aircraft fastener evaluation (SAFE) system: a condition-based corrosion detection system for aging aircraft

Science.gov (United States)

Schoess, Jeffrey N.; Seifert, Greg; Paul, Clare A.

1996-05-01

The smart aircraft fastener evaluation (SAFE) system is an advanced structural health monitoring effort to detect and characterize corrosion in hidden and inaccessible locations of aircraft structures. Hidden corrosion is the number one logistics problem for the U.S. Air Force, with an estimated maintenance cost of $700M per year in 1990 dollars. The SAFE system incorporates a solid-state electrochemical microsensor and smart sensor electronics in the body of a Hi-Lok aircraft fastener to process and autonomously report corrosion status to aircraft maintenance personnel. The long-term payoff for using SAFE technology will be in predictive maintenance for aging aircraft and rotorcraft systems, fugitive emissions applications such as control valves, chemical pipeline vessels, and industrial boilers. Predictive maintenance capability, service, and repair will replace the current practice of scheduled maintenance to substantially reduce operational costs. A summary of the SAFE concept, laboratory test results, and future field test plans is presented.

75 FR 41986 - Certification of Aircraft and Airmen for the Operation of Light-Sport Aircraft; Modifications to...

Science.gov (United States)

2010-07-20

...- Sport Aircraft; Modifications to Rules for Sport Pilots and Flight Instructors With a Sport Pilot Rating... rule; OMB approval of information collection. SUMMARY: This document announces the Office of Management... rule, ``Certification of Aircraft and Airmen for the Operation of Light-Sport Aircraft; Modifications...

Vitamin D controls T cell antigen receptor signaling and activation of human T cells

DEFF Research Database (Denmark)

von Essen, Marina Rode; Kongsbak-Wismann, Martin; Schjerling, Peter

2010-01-01

Phospholipase C (PLC) isozymes are key signaling proteins downstream of many extracellular stimuli. Here we show that naive human T cells had very low expression of PLC-gamma1 and that this correlated with low T cell antigen receptor (TCR) responsiveness in naive T cells. However, TCR triggering...... led to an upregulation of approximately 75-fold in PLC-gamma1 expression, which correlated with greater TCR responsiveness. Induction of PLC-gamma1 was dependent on vitamin D and expression of the vitamin D receptor (VDR). Naive T cells did not express VDR, but VDR expression was induced by TCR...... signaling via the alternative mitogen-activated protein kinase p38 pathway. Thus, initial TCR signaling via p38 leads to successive induction of VDR and PLC-gamma1, which are required for subsequent classical TCR signaling and T cell activation....

Aircraft Cabin Environmental Quality Sensors

Energy Technology Data Exchange (ETDEWEB)

Gundel, Lara; Kirchstetter, Thomas; Spears, Michael; Sullivan, Douglas

2010-05-06

The Indoor Environment Department at Lawrence Berkeley National Laboratory (LBNL) teamed with seven universities to participate in a Federal Aviation Administration (FAA) Center of Excellence (COE) for research on environmental quality in aircraft. This report describes research performed at LBNL on selecting and evaluating sensors for monitoring environmental quality in aircraft cabins, as part of Project 7 of the FAA's COE for Airliner Cabin Environmental Research (ACER)1 effort. This part of Project 7 links to the ozone, pesticide, and incident projects for data collection and monitoring and is a component of a broader research effort on sensors by ACER. Results from UCB and LBNL's concurrent research on ozone (ACER Project 1) are found in Weschler et al., 2007; Bhangar et al. 2008; Coleman et al., 2008 and Strom-Tejsen et al., 2008. LBNL's research on pesticides (ACER Project 2) in airliner cabins is described in Maddalena and McKone (2008). This report focused on the sensors needed for normal contaminants and conditions in aircraft. The results are intended to complement and coordinate with results from other ACER members who concentrated primarily on (a) sensors for chemical and biological pollutants that might be released intentionally in aircraft; (b) integration of sensor systems; and (c) optimal location of sensors within aircraft. The parameters and sensors were selected primarily to satisfy routine monitoring needs for contaminants and conditions that commonly occur in aircraft. However, such sensor systems can also be incorporated into research programs on environmental quality in aircraft cabins.

Impact analysis of composite aircraft structures

Science.gov (United States)

Pifko, Allan B.; Kushner, Alan S.

1993-01-01

The impact analysis of composite aircraft structures is discussed. Topics discussed include: background remarks on aircraft crashworthiness; comments on modeling strategies for crashworthiness simulation; initial study of simulation of progressive failure of an aircraft component constructed of composite material; and research direction in composite characterization for impact analysis.

X-36 Tailless Fighter Agility Research Aircraft on lakebed during high-speed taxi tests

Science.gov (United States)

1996-01-01

-36 prototype weighed approximately 1,250 pounds. It was 19 feet long and three feet high with a wingspan of just over 10 feet. A Williams International F112 turbofan engine provided close to 700 pounds of thrust. A typical research flight lasted 35 to 45 minutes from takeoff to touchdown. A total of 31 successful research flights were flown from May 17, 1997, to November 12, 1997, amassing 15 hours and 38 minutes of flight time. The aircraft reached an altitude of 20,200 feet and a maximum angle of attack of 40 degrees. In a follow-on effort, the Air Force Research Laboratory (AFRL), Wright-Patterson Air Force Base, Ohio, contracted with Boeing to fly AFRL's Reconfigurable Control for Tailless Fighter Aircraft (RESTORE) software as a demonstration of the adaptability of the neural-net algorithm to compensate for in-flight damage or malfunction of effectors, such as flaps, ailerons and rudders. Two RESTORE research flights were flown in December 1998, proving the viability of the software approach. The X-36 aircraft flown at the Dryden Flight Research Center in 1997 was a 28-percent scale representation of a theoretical advanced fighter aircraft. The Boeing Phantom Works (formerly McDonnell Douglas) in St. Louis, Missouri, built two of the vehicles in a cooperative agreement with the Ames Research Center, Moffett Field, California.

8 CFR 1280.21 - Seizure of aircraft.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Seizure of aircraft. 1280.21 Section 1280... REGULATIONS IMPOSITION AND COLLECTION OF FINES § 1280.21 Seizure of aircraft. Seizure of an aircraft under the... that its value is less than the amount of the fine which may be imposed. If seizure of an aircraft for...

8 CFR 280.21 - Seizure of aircraft.

Science.gov (United States)

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Seizure of aircraft. 280.21 Section 280.21... OF FINES § 280.21 Seizure of aircraft. Seizure of an aircraft under the authority of section 239 of... than the amount of the fine which may be imposed. If seizure of an aircraft for violation of section...

38 CFR 38.603 - Gifts and donations.

Science.gov (United States)

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Gifts and donations. 38...) NATIONAL CEMETERIES OF THE DEPARTMENT OF VETERANS AFFAIRS § 38.603 Gifts and donations. (a) Gifts and donations will be accepted only after it has been determined that the donor has a clear understanding that...

GRAPHICAL MODELS OF THE AIRCRAFT MAINTENANCE PROCESS

Directory of Open Access Journals (Sweden)

Stanislav Vladimirovich Daletskiy

2017-01-01

Full Text Available The aircraft maintenance is realized by a rapid sequence of maintenance organizational and technical states, its re- search and analysis are carried out by statistical methods. The maintenance process concludes aircraft technical states con- nected with the objective patterns of technical qualities changes of the aircraft as a maintenance object and organizational states which determine the subjective organization and planning process of aircraft using. The objective maintenance pro- cess is realized in Maintenance and Repair System which does not include maintenance organization and planning and is a set of related elements: aircraft, Maintenance and Repair measures, executors and documentation that sets rules of their interaction for maintaining of the aircraft reliability and readiness for flight. The aircraft organizational and technical states are considered, their characteristics and heuristic estimates of connection in knots and arcs of graphs and of aircraft organi- zational states during regular maintenance and at technical state failure are given. It is shown that in real conditions of air- craft maintenance, planned aircraft technical state control and maintenance control through it, is only defined by Mainte- nance and Repair conditions at a given Maintenance and Repair type and form structures, and correspondingly by setting principles of Maintenance and Repair work types to the execution, due to maintenance, by aircraft and all its units mainte- nance and reconstruction strategies. The realization of planned Maintenance and Repair process determines the one of the constant maintenance component. The proposed graphical models allow to reveal quantitative correlations between graph knots to improve maintenance processes by statistical research methods, what reduces manning, timetable and expenses for providing safe civil aviation aircraft maintenance.

Use of high flip angle in T1-prepared FAST sequences for myocardial perfusion quantification

International Nuclear Information System (INIS)

Vallee, Jean-Paul; Ivancevic, Marko; Lazeyras, Francois; Didier, Dominique; Kasuboski, Larry; Chatelain, Pascal; Righetti, Alberto

2003-01-01

This study reports on the first use of high flip angle and radio-frequency (RF) spoiling in T1-prepared fast acquisition in steady state (FAST) sequence for myocardial perfusion in patients. T1 dynamic range was measured in vitro with a FAST, an RF FAST and a snapshot fast low-angle shot (FLASH) sequences with a 90 flip angle. Myocardial perfusion was then measured twice in 6 patients during the same MR session. The RF FAST and FLASH, but not the FAST sequence, demonstrated an extended T1 dynamic range; however, the FLASH images were degraded by artifacts not present on the RF FAST images. The myocardial perfusion indices K1 (first-order transfer constant from the blood to the myocardium for the Gd-DTPA) and Vd (distribution volume of Gd-DTPA in myocardium) did not differ significantly between the two injections. K1 was 0.48±0.12 ml/min g -1 and Vd was 12.5±2.9%. With an extended T1 dynamic range and the sensitivity required for myocardial perfusion quantification, the RF FAST sequence with a 90 flip angle outperformed the snapshot FLASH sequence in terms of image quality and the FAST sequence in terms of contrast dynamic range. (orig.)

Principles for Aircraft Energy Mapping

OpenAIRE

Berg, Frederick T N

2013-01-01

An increasing emphasis on energy eciency in aircraft systems has in recentyears led to greater interest in integrated design and optimisation withinthe industry. New tools are needed to understand, compare and manage energyuse of an aircraft throughout its design and operation. This thesis describes a new methodology to meet this need: aircraft exergy mapping.The choice of exergy, a 2nd law metric, to describe the energy ows is fundamental to the methodology, providing numerous advantages ove...

NDT applications in the aircraft industry

International Nuclear Information System (INIS)

Aguilar, E.C.

1994-01-01

Non-destructive testing (NDT) in the aircraft industry is used primarily to detect process defects in the manufacturing stage and failure defects in the in-service stage. Inspection techniques such as X- or gamma ray radiography are used for examination. Eddy current and ultrasonic are applied for examination, fluorescent penetrant and magnetic particles are applied for examination of aircraft and engine. With the wide scope of application, this paper discussed one type of NDT that is much used in aircraft being the latest technique in aircraft manufacturing. 1 fig

Composite materials for aircraft structures

National Research Council Canada - National Science Library

Baker, A. A; Dutton, Stuart; Kelly, Donald

2004-01-01

... materials for aircraft structures / Alan Baker, Stuart Dutton, and Donald Kelly- 2nd ed. p. cm. - (Education series) Rev. ed. of: Composite materials for aircraft structures / edited by B. C. Hos...

Description of an aircraft lightning and simulated nuclear electromagnetic pulse (NEMP) threat based on experimental data

Science.gov (United States)

Rustan, Pedro L., Jr.

1987-01-01

Lightning data obtained by measuring the surface electromagnetic fields on a CV-580 research aircraft during 48 lightning strikes between 1500 and 18,000 feet in central Florida during the summers of 1984 and 1985, and nuclear electromagnetic pulse (NEMP) data obtained by surface electromagnetic field measurements using a 1:74 CV-580 scale model, are presented. From one lightning event, maximum values of 3750 T/s for the time rate of change of the surface magnetic flux density, and 4.7 kA for the peak current, were obtained. From the simulated NEMP test, maximum values of 40,000 T/s for the time rate of change of the surface magnetic flux density, and 90 A/sq m for the total normal current density, were found. The data have application to the development of a military aircraft lightning/NEMP standard.

Standard Test Method for Preparing Aircraft Cleaning Compounds, Liquid Type, Water Base, for Storage Stability Testing

CERN Document Server

American Society for Testing and Materials. Philadelphia

2002-01-01

1.1 This test method covers the determination of the stability in storage, of liquid, water-base chemical cleaning compounds, used to clean the exterior surfaces of aircraft. 1.2 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

IDENTIFICATION OF AIRCRAFT HAZARDS

International Nuclear Information System (INIS)

K.L. Ashley

2005-01-01

Aircraft hazards were determined to be potentially applicable to a repository at Yucca Mountain in the ''Monitored Geological Repository External Events Hazards Screening Analysis'' (BSC 2004, Section 6.4.1). That determination was conservatively based on limited knowledge of flight data in the area of concern and on crash data for aircraft of the type flying near Yucca Mountain. The purpose of this report is to identify specific aircraft hazards that may be applicable to a Monitored Geologic Repository (MGR) at Yucca Mountain using NUREG-0800, ''Standard Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants'' (NRC 1987, Section 3.5.1.6), as guidance for the inclusion or exclusion of identified aircraft hazards. NUREG-0800 is being used here as a reference because some of the same considerations apply. The intended use of this report is to provide inputs for further screening and analysis of the identified aircraft hazards based on the criteria that apply to Category 1 and 2 event sequence analyses as defined in 10 CFR 63.2 (see Section 4). The scope of this technical report includes the evaluation of military, private, and commercial use of airspace in the 100-mile regional setting of the MGR at Yucca Mountain with the potential for reducing the regional setting to a more manageable size after consideration of applicable screening criteria (see Section 7)

Identification of Aircraft Hazards

Energy Technology Data Exchange (ETDEWEB)

K. Ashley

2006-12-08

Aircraft hazards were determined to be potentially applicable to a repository at Yucca Mountain in ''Monitored Geological Repository External Events Hazards Screening Analysis'' (BSC 2005 [DIRS 174235], Section 6.4.1). That determination was conservatively based upon limited knowledge of flight data in the area of concern and upon crash data for aircraft of the type flying near Yucca Mountain. The purpose of this report is to identify specific aircraft hazards that may be applicable to a monitored geologic repository (MGR) at Yucca Mountain, using NUREG-0800, ''Standard Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants'' (NRC 1987 [DIRS 103124], Section 3.5.1.6), as guidance for the inclusion or exclusion of identified aircraft hazards. The intended use of this report is to provide inputs for further screening and analysis of identified aircraft hazards based upon the criteria that apply to Category 1 and Category 2 event sequence analyses as defined in 10 CFR 63.2 [DIRS 176544] (Section 4). The scope of this report includes the evaluation of military, private, and commercial use of airspace in the 100-mile regional setting of the repository at Yucca Mountain with the potential for reducing the regional setting to a more manageable size after consideration of applicable screening criteria (Section 7).

31 CFR 560.528 - Aircraft safety.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Aircraft safety. 560.528 Section 560..., Authorizations and Statements of Licensing Policy § 560.528 Aircraft safety. Specific licenses may be issued on a... the safety of civil aviation and safe operation of U.S.-origin commercial passenger aircraft. ...

26 CFR 1.956-2T - Definition of United States Property (temporary).

Science.gov (United States)

2010-04-01

...). 1.956-2T Section 1.956-2T Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Controlled Foreign Corporations § 1.956-2T Definition of...(a) through (b)(1)(v). (vi) Any aircraft, railroad rolling stock, vessel, motor vehicle, or container...

Saussurea tridactyla Sch. Bip.-derived polysaccharides and flavones reduce oxidative damage in ultraviolet B-irradiated HaCaT cells via a p38MAPK-independent mechanism

Directory of Open Access Journals (Sweden)

Guo Y

2016-01-01

Full Text Available Yan Guo,1 Juan Sun,2 Juan Ye,1 Wenyu Ma,1 Hualing Yan,1 Gang Wang1 1Department of Dermatology and Venereology, Affiliated Hospital of Qinghai University, 2Department of Anatomy, Qinghai University Medical College, Xining, People’s Republic of China Objective: To investigate whether Saussurea tridactyla Sch. Bip.-derived polysaccharides and flavones exert apoptosis-inhibiting effects in ultraviolet B (UVB-irradiated HaCaT cells.Methods: We divided HaCaT cells into low radiation UVB and high radiation UVB groups. Low radiation UVB and high radiation UVB groups were further divided into a control group, UVB radiation group (UVB group, S. tridactyla Sch. Bip.-derived polysaccharides and flavones low-dose group, and S. tridactyla Sch. Bip.-derived polysaccharides and flavones high-dose group. Cell viability and morphology were assayed by MTT and trypan blue staining. Superoxide dismutase activity, glutathione content, malondialdehyde content, and catalase activity test kits were used to detect superoxide dismutase activity, glutathione content, malondialdehyde content, and catalase activity, respectively. Cell apoptosis, intracellular Ca2+ levels, and mitochondrial membrane potential (ΔΨ were detected by flow cytometry. Protein levels were analyzed by Western blotting and immunofluorescence.Results: S. tridactyla Sch. Bip.-derived polysaccharides and flavones were found to increase the absorbance of MTT, decrease cell death, alleviate the degree of cell edema, restore the cell morphology, reduce cell death fragments and chip phenomenon, increase superoxide dismutase activity, glutathione content, and catalase activity while decreasing the content of malondialdehyde, lowering the population of apoptotic cells, reducing the intracellular Ca2+ fluorescence, increasing the mitochondrial membrane potential (ΔΨ, increasing the expressions of p-38, p-53, Bcl-2, and decreasing the expressions of Bax and active-caspase-3.Conclusion: S. tridactyla Sch

Charged particle spectra in π-p,π-d and π-C interactions at 38 GeV/c with single-particle high pT trigger

International Nuclear Information System (INIS)

Boos, E.G.; Mosienko, A.M.; Baerwolff, H.

1987-01-01

Angular momentum distributions of charged secondaries from 38 GeV/c π - p, π - d and π - C interactions triggered on at least one particle with p T >or approx. 1 GeV/c at an 90 deg πN c.m.s angle have been investigated with the spectrometer RISK (a streamer chamber placed into a magnet). Transversal momentum spectra of secondaries in the 0.4-2.4 GeV/c p T -range including triggering particles are quite well fitted with the exponential function for all nuclei studied and for particles of different charges. The azimuthal angle distribution of secondaries (an angle relative to the p T -tilde of the triggering particle) for both trigger-like and trigger-unlike charges is anisotropic, preferring the direction away from the triggering particle. The mean charge distribution of associated particles is discussed. A small fraction of triggering particles is due to neutral strange particle decays. Many Λ 0 -hyperons were detected among those neutral strange triggers

Aircraft accident report: NASA 712, Convair 990, N712NA, March Air Force Base, California, July 17, 1985, facts and analysis

Science.gov (United States)

Batthauer, Byron E.; Mccarthy, G. T.; Hannah, Michael; Hogan, Robert J.; Marlow, Frank J.; Reynard, William D.; Stoklosa, Janis H.; Yager, Thomas J.

1986-01-01

On July 17, l985, at 1810 P.d.t., NASA 712, a Convair 990 aircraft, was destroyed by fire at March Air Force Base, California. The fire started during the rollout after the pilot rejected the takeoff on runway 32. The rejected takeoff was initiated during the takeoff roll because of blown tires on the right landing gear. During the rollout, fragments of either the blown tires or the wheel/brake assemblies penetrated a right-wing fuel tank forward of the right main landing gear. Leaking fuel ignited while the aircraft was rolling, and fire engulfed the right wing and the fuselage after the aircraft was stopped on the runway. The 4-man flightcrew and the 15 scientists and technicians seated in the cabin evacuated the aircraft without serious injury. The fire was not extinguished by crash/rescue efforts and the aircraft was destroyed.

Design definition study of a lift/cruise fan technology V/STOL aircraft. Volume 1: Navy operational aircraft

Science.gov (United States)

1975-01-01

Aircraft were designed and sized to meet Navy mission requirements. Five missions were established for evaluation: anti-submarine warfare (ASW), surface attack (SA), combat search and rescue (CSAR), surveillance (SURV), and vertical on-board delivery (VOD). All missions were performed with a short takeoff and a vertical landing. The aircraft were defined using existing J97-GE gas generators or reasonable growth derivatives in conjunction with turbotip fans reflecting LF460 type technology. The multipurpose aircraft configuration established for U.S. Navy missions utilizes the turbotip driven lift/cruise fan concept for V/STOL aircraft.

Alternate Fuels for Use in Commercial Aircraft

Science.gov (United States)

Daggett, David L.; Hendricks, Robert C.; Walther, Rainer; Corporan, Edwin

2008-01-01

The engine and aircraft Research and Development (R&D) communities have been investigating alternative fueling in near-term, midterm, and far-term aircraft. A drop in jet fuel replacement, consisting of a kerosene (Jet-A) and synthetic fuel blend, will be possible for use in existing and near-term aircraft. Future midterm aircraft may use a biojet and synthetic fuel blend in ultra-efficient airplane designs. Future far-term engines and aircraft in 50-plus years may be specifically designed to use a low- or zero-carbon fuel. Synthetic jet fuels from coal, natural gas, or other hydrocarbon feedstocks are very similar in performance to conventional jet fuel, yet the additional CO2 produced during the manufacturing needs to be permanently sequestered. Biojet fuels need to be developed specifically for jet aircraft without displacing food production. Envisioned as midterm aircraft fuel, if the performance and cost liabilities can be overcome, biofuel blends with synthetic jet or Jet-A fuels have near-term potential in terms of global climatic concerns. Long-term solutions address dramatic emissions reductions through use of alternate aircraft fuels such as liquid hydrogen or liquid methane. Either of these new aircraft fuels will require an enormous change in infrastructure and thus engine and airplane design. Life-cycle environmental questions need to be addressed.

Technology Trends in Small Unmanned Aircraft Systems (sUAS) and Counter-UAS: A Five Year Outlook

Science.gov (United States)

2017-11-01

I N S T I T U T E F O R D E F E N S E ANALYSES Technology Trends in Small Unmanned Aircraft Systems (sUAS) and Counter-UAS: A Five-Year Outlook...the copyright license under the clause at DFARS 252.227-7013 (a)(16) [June 2013]. INSTITUTE FOR DEFENSE ANALYSES IDA Paper P-8823 Technology Trends...threats to infrastructure posed across all domains—air, land, sea, and cyber. Although threats and technologies are rapidly evolving across all

Aircraft gas turbines

Energy Technology Data Exchange (ETDEWEB)

Arai, M [Kawasaki Heavy Industries Ltd., Kobe (Japan)

1995-03-01

Recently the international relationship has been playing an important role in the research, development and production of the aircraft gas turbine. The YSX, which is supposed to be the 100-seat class commercial aircraft, has been planned by Japan Aircraft Development (JADC) as an international cooperative project. Recently many western aeroengine companies have offered the collaboration of small turbofan engines which would be installed on YSX to Japanese aeroengine companies (IHI, KHI and MHI). The YSX is powered by 16,000-20,000 1bs thrust class engines. As for medium turbofan engine (V2500), the V 2500 family of 22,000 to 30,000 1bs thrust has been developed since 1983 through international collaboration by seven aeroengine companies in five nations. In this paper, the recent Japan`s activities of the research, development and production with viewing the world-wide movement, are described. 6 figs.

Hazards from aircraft

International Nuclear Information System (INIS)

Grund, J.E.; Hornyik, K.

1975-01-01

The siting of nuclear power plants has created innumerable environmental concerns. Among the effects of the ''man-made environment'' one of increasing importance in recent nuclear plant siting hazards analysis has been the concern about aircraft hazards to the nuclear plant. These hazards are of concern because of the possibility that an aircraft may have a malfunction and crash either near the plant or directly into it. Such a crash could be postulated to result, because of missile and/or fire effects, in radioactive releases which would endanger the public health and safety. The majority of studies related to hazards from air traffic have been concerned with the determination of the probability associated with an aircraft striking vulnerable portions of a given plant. Other studies have focused on the structural response to such a strike. This work focuses on the problem of strike probability. 13 references

Numerical and Experimental Analysis of Aircraft Wing Subjected to Fatigue Loading

Directory of Open Access Journals (Sweden)

Hatem Rahim Wasmi

2016-10-01

Full Text Available This study deals with the aircraft wing analysis (numerical and experimental which subjected to fatigue loading in order to analyze the aircraft wing numerically by using ANSYS 15.0 software and experimentally by using loading programs which effect on fatigue test specimens at laboratory to estimate life of used metal (aluminum alloy 7075-T651 the wing metal and compare between numerical and experimental work, as well as to formulate an experimental mathematical model which may find safe estimate for metals and most common alloys that are used to build aircraft wing at certain conditions. In experimental work, a (34 specimen of (aluminum alloy 7075-T651 were tested using alternating bending fatigue machine rig. The test results are ; (18 Specimen to establish the (S-N curve and endurance limit and the other specimens used for variable amplitude tests were represented by loading programs which represents actual flight conditions. Also it has been obtained the safe fatigue curves which are described by mathematical formulas. ANSYS results show convergence with experimental results about cumulative fatigue damage (D, a mathematical model is proposed to estimate the life; this model gives good results in case of actual loading programs. Also, Miner and Marsh rules are applied to the specimens and compared with the proposal mathematical model in order to estimate the life of the wing material under actual flight loading conditions, comparing results show that it is possible to depend on present mathematical model than Miner and Marsh theories because the proposal mathematical model shows safe and good results compared with experimental work results.

Perspectives on Highly Adaptive or Morphing Aircraft

Science.gov (United States)

McGowan, Anna-Maria R.; Vicroy, Dan D.; Busan, Ronald C.; Hahn, Andrew S.

2009-01-01

The ability to adapt to different flight conditions has been fundamental to aircraft design since the Wright Brothers first flight. Over a hundred years later, unconventional aircraft adaptability, often called aircraft morphing has become a topic of considerable renewed interest. In the past two decades, this interest has been largely fuelled by advancements in multi-functional or smart materials and structures. However, highly adaptive or morphing aircraft is certainly a cross-discipline challenge that stimulates a wide range of design possibilities. This paper will review some of the history of morphing aircraft including recent research programs and discuss some perspectives on this work.

Small Transport Aircraft Technology /STAT/ Propulsion Study

Science.gov (United States)

Heldenbrand, R. W.; Baerst, C. F.; Rowse, J. H.

1980-01-01

The NASA Small Transport Aircraft Technology (STAT) Propulsion Study was established to identify technology requirements and define the research and development required for new commuter aircraft. Interim results of the studies defined mission and design characteristics for 30- and 50-passenger aircraft. Sensitivities were defined that relate changes in engine specific fuel consumption (SFC), weight, and cost (including maintenance) to changes in the aircraft direct operating cost (DOC), takeoff gross weight, and empty weight. A comparison of performance and economic characteristics is presented between aircraft powered by 1980 production engines and those powered by a 1990 advanced technology baseline engine.

Aircraft vulnerability analysis by modeling and simulation

Science.gov (United States)

Willers, Cornelius J.; Willers, Maria S.; de Waal, Alta

2014-10-01

Infrared missiles pose a significant threat to civilian and military aviation. ManPADS missiles are especially dangerous in the hands of rogue and undisciplined forces. Yet, not all the launched missiles hit their targets; the miss being either attributable to misuse of the weapon or to missile performance restrictions. This paper analyses some of the factors affecting aircraft vulnerability and demonstrates a structured analysis of the risk and aircraft vulnerability problem. The aircraft-missile engagement is a complex series of events, many of which are only partially understood. Aircraft and missile designers focus on the optimal design and performance of their respective systems, often testing only in a limited set of scenarios. Most missiles react to the contrast intensity, but the variability of the background is rarely considered. Finally, the vulnerability of the aircraft depends jointly on the missile's performance and the doctrine governing the missile's launch. These factors are considered in a holistic investigation. The view direction, altitude, time of day, sun position, latitude/longitude and terrain determine the background against which the aircraft is observed. Especially high gradients in sky radiance occur around the sun and on the horizon. This paper considers uncluttered background scenes (uniform terrain and clear sky) and presents examples of background radiance at all view angles across a sphere around the sensor. A detailed geometrical and spatially distributed radiometric model is used to model the aircraft. This model provides the signature at all possible view angles across the sphere around the aircraft. The signature is determined in absolute terms (no background) and in contrast terms (with background). It is shown that the background significantly affects the contrast signature as observed by the missile sensor. A simplified missile model is constructed by defining the thrust and mass profiles, maximum seeker tracking rate, maximum

Daedalus Project's Light Eagle - Human powered aircraft

Science.gov (United States)

1987-01-01

The Michelob Light Eagle is seen here in flight over Rogers Dry Lake at the NASA Dryden Flight Research Center, Edwards, California. The Light Eagle and Daedalus human powered aircraft were testbeds for flight research conducted at Dryden between January 1987 and March 1988. These unique aircraft were designed and constructed by a group of students, professors, and alumni of the Massachusetts Institute of Technology within the context of the Daedalus project. The construction of the Light Eagle and Daedalus aircraft was funded primarily by the Anheuser Busch and United Technologies Corporations, respectively, with additional support from the Smithsonian Air and Space Museum, MIT, and a number of other sponsors. To celebrate the Greek myth of Daedalus, the man who constructed wings of wax and feathers to escape King Minos, the Daedalus project began with the goal of designing, building and testing a human-powered aircraft that could fly the mythical distance, 115 km. To achieve this goal, three aircraft were constructed. The Light Eagle was the prototype aircraft, weighing 92 pounds. On January 22, 1987, it set a closed course distance record of 59 km, which still stands. Also in January of 1987, the Light Eagle was powered by Lois McCallin to set the straight distance, the distance around a closed circuit, and the duration world records for the female division in human powered vehicles. Following this success, two more aircraft were built, the Daedalus 87 and Daedalus 88. Each aircraft weighed approximately 69 pounds. The Daedalus 88 aircraft was the ship that flew the 199 km from the Iraklion Air Force Base on Crete in the Mediterranean Sea, to the island of Santorini in 3 hours, 54 minutes. In the process, the aircraft set new records in distance and endurance for a human powered aircraft. The specific areas of flight research conducted at Dryden included characterizing the rigid body and flexible dynamics of the Light Eagle, investigating sensors for an

Structural design for aircraft impact loading

International Nuclear Information System (INIS)

Schmidt, R.; Heckhausen, H.; Chen, C.; Rieck, P.J.; Lemons, G.W.

1977-01-01

The Soft Shell-Hardcore approach to nuclear power plant auxiliary structure design was developed to attenuate the crash effects of impacting aircraft. This report is an initial investigation into defining the important structural features involved that would allow the Soft Shell-Hardcore design to successfully sustain the postulated aircraft impact. Also specified for purposes of this study are aircraft impact locations and the type and velocity of impacting aircraft. The purpose of this initial investigation is to determine the feasibility of the two 0.5 m thick walls of the Soft Shell with the simplest possible mathematical model

Numerical simulation of the laser welding process for the prediction of temperature distribution on welded aluminium aircraft components

Science.gov (United States)

Tsirkas, S. A.

2018-03-01

The present investigation is focused to the modelling of the temperature field in aluminium aircraft components welded by a CO2 laser. A three-dimensional finite element model has been developed to simulate the laser welding process and predict the temperature distribution in T-joint laser welded plates with fillet material. The simulation of the laser beam welding process was performed using a nonlinear heat transfer analysis, based on a keyhole formation model analysis. The model employs the technique of element ;birth and death; in order to simulate the weld fillet. Various phenomena associated with welding like temperature dependent material properties and heat losses through convection and radiation were accounted for in the model. The materials considered were 6056-T78 and 6013-T4 aluminium alloys, commonly used for aircraft components. The temperature distribution during laser welding process has been calculated numerically and validated by experimental measurements on different locations of the welded structure. The numerical results are in good agreement with the experimental measurements.

GRAPHICAL MODELS OF THE AIRCRAFT MAINTENANCE PROCESS

OpenAIRE

Stanislav Vladimirovich Daletskiy; Stanislav Stanislavovich Daletskiy

2017-01-01

The aircraft maintenance is realized by a rapid sequence of maintenance organizational and technical states, its re- search and analysis are carried out by statistical methods. The maintenance process concludes aircraft technical states con- nected with the objective patterns of technical qualities changes of the aircraft as a maintenance object and organizational states which determine the subjective organization and planning process of aircraft using. The objective maintenance pro- cess is ...

Dynamic magnetic resonance of pelvic floor: experience in 38 patients

International Nuclear Information System (INIS)

Ocantos, Jorge; Fattal Jaef, Virginia; Pietrani, Marcelo; Seclen, Maria F.; Seehaus, Alberto; Sarsotti, Carlos

2005-01-01

Purpose: To show the experience in the evaluation of dysfunctions of pelvic floor by dynamic magnetic resonance (DMR) and to describe the structural and dynamic disorders of pelvis organs. Material and Methods: From March 2004 to March 2005 38 patients with pelvic floor disorders have been studied, 33/38 women (86, 84 %) and 5/38 men (15,16 %), ages between 16 and 74 years old. An evacuating rectal enema has been indicated 4 hours before the examination with bladder retention of 3 hours. 180-240 cc of semisolid paste (thin oats and saline solution) has been used to distend rectum until patients refer sensation of rectum full or a maximum of 240 cm 3 . The study has been performed in a Siemens Magnetom Vision (1.5 T) body array and coil CP Body Array Flex. T2 turbo spin eco axial and sagittal (TR 4700, TE1, 32), T1 coronal (TR 580 TE 14) with a 4 mm slice were selected for static sequences and Siemens TRUFI sagittal (TR 4.8 TE 2.3) for dynamic acquisitions during rectal and voiding evacuations. The morphology and symmetry of peri urethral ligaments (PUL), elevator anus muscle (LA), and vagina (V) was evaluated. The organs prolapse was evaluated at rest and maximal pelvis strain in accord with Comiter parameters (Fielding J.R.). Results: At 10/38 (26, 32 %) patients was not detected lesions. In 28/38 P (73,68 %) 75 defects of the pelvic supports (54,6 % of LA, 14,6% of the vagina V, 9,3% of PUL and other 21,3 %). The dynamic sequences show 59 defects, 50, 84 % of posterior compartment and 49,16% of anterior. In 8/38 (28, 57 %) patients the lesions affected both compartment. Conclusion: Dynamic magnetic resonance allows the direct interpretation of the very small pelvic floor structure and its disorders (not available by other methods) and the dynamic study of prolapse, providing a more accurate interpretation of its causes. DRM can be very useful in patients with multi-compartment involvement, complex prolapse or recurrence of symptoms post surgical repair. (author

38 CFR 21.3041 - Periods of eligibility; child.

Science.gov (United States)

2010-07-01

...; child. 21.3041 Section 21.3041 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... 38 U.S.C. Chapter 35 Eligibility and Entitlement § 21.3041 Periods of eligibility; child. (a) Eligibility derived from a veteran with a P&T disability. An eligible child's period of eligibility generally...

Radioiodination of peptide hormones and immunoglobuline preparations: comparison of the chloramine T and Iodogen method

Energy Technology Data Exchange (ETDEWEB)

Woltanski, K P; Besch, W; Keilacker, H; Ziegler, M; Kohnert, K D [Zentralinstitut fuer Diabetes, Karlsburg (German Democratic Republic)

1990-02-01

Following optimization of the reaction conditions, e.g. concentration of oxidizing agents, reaction time, volume of reaction mixture, and pH, chloramine T and the new iodination reagent, Iodogen, were compared for their effectiveness in radioiodination of insulin, glucagon, human growth hormone (hGH), and rabbit anti-mouse IgG. The radioactive peptide hormones prepared were analyzed for the presence of aggregate and breakdown products by polyacrylamide gel electrophoresis (PAGE) at pH 8.9, the rabbit anti-mouse IgG was tested for the presence of low molecular weight damage products by gel filtration on Sephadex G-50. The results demonstrate that with respect to iodine incorporation, specific activity, and immunological reactivity either method can be used to prepare under carefully controlled conditions a wide range of tracers with high specific activity at minimal oxidation damage. These tracers are shown to be highly suitable in radioimmunoassays after previous purification by PAGE and gel filtration, respectively. (author).

A Grounded Theory Study of Aircraft Maintenance Technician Decision-Making

Science.gov (United States)

Norcross, Robert

Aircraft maintenance technician decision-making and actions have resulted in aircraft system errors causing aircraft incidents and accidents. Aircraft accident investigators and researchers examined the factors that influence aircraft maintenance technician errors and categorized the types of errors in an attempt to prevent similar occurrences. New aircraft technology introduced to improve aviation safety and efficiency incur failures that have no information contained in the aircraft maintenance manuals. According to the Federal Aviation Administration, aircraft maintenance technicians must use only approved aircraft maintenance documents to repair, modify, and service aircraft. This qualitative research used a grounded theory approach to explore the decision-making processes and actions taken by aircraft maintenance technicians when confronted with an aircraft problem not contained in the aircraft maintenance manuals. The target population for the research was Federal Aviation Administration licensed aircraft and power plant mechanics from across the United States. Nonprobability purposeful sampling was used to obtain aircraft maintenance technicians with the experience sought in the study problem. The sample population recruitment yielded 19 participants for eight focus group sessions to obtain opinions, perceptions, and experiences related to the study problem. All data collected was entered into the Atlas ti qualitative analysis software. The emergence of Aircraft Maintenance Technician decision-making themes regarding Aircraft Maintenance Manual content, Aircraft Maintenance Technician experience, and legal implications of not following Aircraft Maintenance Manuals surfaced. Conclusions from this study suggest Aircraft Maintenance Technician decision-making were influenced by experience, gaps in the Aircraft Maintenance Manuals, reliance on others, realizing the impact of decisions concerning aircraft airworthiness, management pressures, and legal concerns

Mission Analysis and Aircraft Sizing of a Hybrid-Electric Regional Aircraft

Science.gov (United States)

Antcliff, Kevin R.; Guynn, Mark D.; Marien, Ty V.; Wells, Douglas P.; Schneider, Steven J.; Tong, Michael T.

2016-01-01

The purpose of this study was to explore advanced airframe and propulsion technologies for a small regional transport aircraft concept (approximately 50 passengers), with the goal of creating a conceptual design that delivers significant cost and performance advantages over current aircraft in that class. In turn, this could encourage airlines to open up new markets, reestablish service at smaller airports, and increase mobility and connectivity for all passengers. To meet these study goals, hybrid-electric propulsion was analyzed as the primary enabling technology. The advanced regional aircraft is analyzed with four levels of electrification, 0 percent electric with 100 percent conventional, 25 percent electric with 75 percent conventional, 50 percent electric with 50 percent conventional, and 75 percent electric with 25 percent conventional for comparison purposes. Engine models were developed to represent projected future turboprop engine performance with advanced technology and estimates of the engine weights and flowpath dimensions were developed. A low-order multi-disciplinary optimization (MDO) environment was created that could capture the unique features of parallel hybrid-electric aircraft. It is determined that at the size and range of the advanced turboprop: The battery specific energy must be 750 watt-hours per kilogram or greater for the total energy to be less than for a conventional aircraft. A hybrid vehicle would likely not be economically feasible with a battery specific energy of 500 or 750 watt-hours per kilogram based on the higher gross weight, operating empty weight, and energy costs compared to a conventional turboprop. The battery specific energy would need to reach 1000 watt-hours per kilogram by 2030 to make the electrification of its propulsion an economically feasible option. A shorter range and/or an altered propulsion-airframe integration could provide more favorable results.

Aircraft vulnerability analysis by modelling and simulation

CSIR Research Space (South Africa)

Willers, CJ

2014-09-01

Full Text Available attributable to misuse of the weapon or to missile performance restrictions. This paper analyses some of the factors affecting aircraft vulnerability and demonstrates a structured analysis of the risk and aircraft vulnerability problem. The aircraft...

Chemical aspects of the radioactive decay 38S to 38Cl

International Nuclear Information System (INIS)

Leurs, C.J.

1978-01-01

The cyclotron-production of 38 S with the reaction 40 Ar(p,3p) 38 S is described. An excitation curve for this nuclear reaction is given and the chemistry used to produce sulfates labeled with 38 S and H 2 38 S is described. The probability distribution of the recoil energy of 38 Cl, produced by beta-decay of 38 S, is given. The probability for rupture of the original bonds due to the radioactive decay process, is estimated for gaseous H 2 38 S and for crystalline sulfates- 38 S. The results are given for the β,γ-decay of 38 S to 38 Cl under different circumstances in inorganic solid sulfates (with and without water of crystallization) and in the mixed crystal K 2 SO 4 .K 2 BeF 4 (1 : 2500). Finally, the reactions of 38 Cl, produced by radioactive decay of 38 S (as H 2 38 S) with gaseous 1,2-dichloroethylene are discussed

Icaritin induces MC3T3-E1 subclone14 cell differentiation through estrogen receptor-mediated ERK1/2 and p38 signaling activation.

Science.gov (United States)

Wu, Zhidi; Ou, Ling; Wang, Chaopeng; Yang, Li; Wang, Panpan; Liu, Hengrui; Xiong, Yingquan; Sun, Kehuan; Zhang, Ronghua; Zhu, Xiaofeng

2017-10-01

Icaritin (ICT), a hydrolytic product of icariin from the genus Epimedium, has many indicated pharmacological and biological activities. Several studies have shown that ICT has potential osteoprotective effects, including stimulation of osteoblast differentiation and inhibition of osteoclast differentiation. However, the molecular mechanism for this anabolic action of ICT remains largely unknown. Here, we found that ICT could enhance MC3T3-E1 subclone 14 preosteoblastic cell differentiation associated with increased mRNA levels and protein expression of the differentiation markers alkaline phosphatase (ALP), type 1 collagen (COL1), osteocalcin (OC), osteoponin (OPN) and runt-related transcription factor 2 (RUNX2), and improved mineralization, confirmed by bone nodule formation and collagen synthesis. To characterize the underlying mechanisms, we examined the effect of ICT on estrogen receptor (ER) and mitogen-activated protein kinase (MAPK) signaling. ICT treatment induced p38 kinase and extracellular signal-regulated kinase 1/2 (ERK1/2) activation, but it demonstrated at the same time point no effect on activation of c-Jun N-terminal kinase (JNK). ER antagonist ICI182780, p38 antagonist SB203580 and ERK1/2 antagonist PD98059 markedly inhibited the ICT-induced the mRNA expression of ALP, COL1, OC and OPN. ICI182780 attenuated the ICT-induced phosphorylation of p38 and ERK1/2. These observations indicate a potential mechanism of osteogenic effects of ICT involving the ERK1/2 and p38 pathway activation through the ER. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Analyses of Aircraft Responses to Atmospheric Turbulence

NARCIS (Netherlands)

Van Staveren, W.H.J.J.

2003-01-01

The response of aircraft to stochastic atmospheric turbulence plays an important role in aircraft-design (load calculations), Flight Control System (FCS) design and flight-simulation (handling qualities research and pilot training). In order to simulate these aircraft responses, an accurate

Common factors in the withdrawal of European aircraft manufacturers from the regional aircraft market

NARCIS (Netherlands)

Heerkens, Johannes M.G.; de Bruijn, E.J.; Steenhuis, H.J.

2010-01-01

We investigate whether there were common causes for the withdrawal from the regional aircraft market of three established manufacturers (BAE Systems, Fokker and Saab), while competitors thrived. We focus on the markets for 50- and 100-seat aircraft. One cause concerning the 50-seat market was the

Tropical cyclones-Pacific Asian Research Campaign for Improvement of Intensity estimations/forecasts (T-PARCII): A research plan of typhoon aircraft observations in Japan

Science.gov (United States)

Tsuboki, Kazuhisa

2017-04-01

Typhoons are the most devastating weather system occurring in the western North Pacific and the South China Sea. Violent wind and heavy rainfall associated with a typhoon cause huge disaster in East Asia including Japan. In 2013, Supertyphoon Haiyan struck the Philippines caused a very high storm surge and more than 7000 people were killed. In 2015, two typhoons approached the main islands of Japan and severe flood occurred in the northern Kanto region. Typhoons are still the largest cause of natural disaster in East Asia. Moreover, many researches have projected increase of typhoon intensity with the climate change. This suggests that a typhoon risk is increasing in East Asia. However, the historical data of typhoon include large uncertainty. In particular, intensity data of the most intense typhoon category have larger error after the US aircraft reconnaissance of typhoon was terminated in 1987.The main objective of the present study is improvements of typhoon intensity estimations and of forecasts of intensity and track. We will perform aircraft observation of typhoon and the observed data are assimilated to numerical models to improve intensity estimation. Using radars and balloons, observations of thermodynamical and cloud-microphysical processes of typhoons will be also performed to improve physical processes of numerical model. In typhoon seasons (mostly in August and September), we will perform aircraft observations of typhoons. Using dropsondes from the aircraft, temperature, humidity, pressure, and wind are measured in surroundings of the typhoon inner core region. The dropsonde data are assimilated to a cloud-resolving model which has been developed in Nagoya University and named the Cloud Resolving Storm Simulator (CReSS). Then, more accurate estimations and forecasts of the typhoon intensity will be made as well as typhoon tracks. Furthermore, we will utilize a ground-based balloon with microscope camera, X-band precipitation radar, Ka-band cloud radar

Advanced technology for future regional transport aircraft

Science.gov (United States)

Williams, L. J.

1982-01-01

In connection with a request for a report coming from a U.S. Senate committee, NASA formed a Small Transport Aircraft Technology (STAT) team in 1978. STAT was to obtain information concerning the technical improvements in commuter aircraft that would likely increase their public acceptance. Another area of study was related to questions regarding the help which could be provided by NASA's aeronautical research and development program to commuter aircraft manufacturers with respect to the solution of technical problems. Attention is given to commuter airline growth, current commuter/region aircraft and new aircraft in development, prospects for advanced technology commuter/regional transports, and potential benefits of advanced technology. A list is provided of a number of particular advances appropriate to small transport aircraft, taking into account small gas turbine engine component technology, propeller technology, three-dimensional wing-design technology, airframe aerodynamics/propulsion integration, and composite structure materials.

A miniature powerplant for very small, very long range autonomous aircraft. Final report

Energy Technology Data Exchange (ETDEWEB)

Tad McGeer

1999-09-29

The authors have developed a new piston engine offering unprecedented efficiency for a new generation of miniature robotic aircraft. Following Phase 1 preliminary design in 1996--97, they have gone forward in Phase 2 to complete detail design, and are nearing completion of a first batch of ten engines. A small-engine dynamometer facility has been built in preparation for the test program. Provisions have been included for supercharging, which will allow operation at ceilings in the 10,000 m range. Component tests and detailed analysis indicate that the engine will achieve brake-specific fuel consumption well below 300 gm/kWh at power levels of several hundred watts. This level of performance opens the door to development of tabletop-sized aircraft having transpacific range and multi-day endurance, which will offer extraordinary new capabilities for meteorology, geomagnetic, and a variety of applications in environmental monitoring and military operations.

Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways

Directory of Open Access Journals (Sweden)

Yang T

2016-04-01

Full Text Available Tingfang Yang,1 Shuluan Yao,2 Xianfeng Zhang,3 Yan Guo2 1Department of Pediatrics, Jining No 1 People’s Hospital, Shandong Province, People’s Republic of China; 2Department of Respiratory Medicine, Jining Medical University Affiliated Hospital, Shandong Province, People’s Republic of China; 3Department of Psychiatry, Jining Psychiatric Hospital, Shandong Province, People’s Republic of China Abstract: T-cell acute lymphoblastic leukemia (T-ALL as a prevalent hematologic malignancy is one of the most common malignant tumors worldwide in children. Andrographolide (Andro, the major active component from Andrographis paniculata, has been shown to possess antitumor activities in several types of cancer cells. However, whether Andro would inhibit T-ALL cell growth remains unclear. In this study, we investigated the cytotoxic effect of Andro on human T-ALL Jurkat cells and explored the mechanisms of cell death. Cell apoptosis was assayed by flow cytometry, and the signaling transduction for Andro was analyzed by Western blotting. The results indicated 10 µg/mL Andro could significantly induce Jurkat cells’ apoptosis, depending on the inhibition of PI3K/AKT pathway. Moreover, Andro-induced apoptosis is enhanced by AKT-selective inhibitor LY294002. ERK- or JNK-selective inhibitors PD98059 and SP600125 had no effect on Andro-induced apoptosis. In addition, p38 inhibitor SB203580 could reverse Andro-induced apoptosis in Jurkat cells. We also found that the protein expression of p-p53 and p-p38 were increased after Andro treatments. The result of an in vivo study also demonstrated Andro’s dose-dependent inhibition in subcutaneous Jurkat xenografts. In conclusion, our findings explained a novel mechanism of drug action by Andro in Jurkat cells and suggested that Andro might be developed into a new candidate therapy for T-ALL patients in the coming days. Keywords: andrographolide, PI3K, AKT, Burkitt lymphoma, Jurkat cell

Method of transition from 3D model to its ontological representation in aircraft design process

Science.gov (United States)

Govorkov, A. S.; Zhilyaev, A. S.; Fokin, I. V.

2018-05-01

This paper proposes the method of transition from a 3D model to its ontological representation and describes its usage in the aircraft design process. The problems of design for manufacturability and design automation are also discussed. The introduced method is to aim to ease the process of data exchange between important aircraft design phases, namely engineering and design control. The method is also intended to increase design speed and 3D model customizability. This requires careful selection of the complex systems (CAD / CAM / CAE / PDM), providing the basis for the integration of design and technological preparation of production and more fully take into account the characteristics of products and processes for their manufacture. It is important to solve this problem, as investment in the automation define the company's competitiveness in the years ahead.

Control of Next Generation Aircraft and Wind Turbines

Science.gov (United States)

Frost, Susan

2010-01-01

The first part of this talk will describe some of the exciting new next generation aircraft that NASA is proposing for the future. These aircraft are being designed to reduce aircraft fuel consumption and environmental impact. Reducing the aircraft weight is one approach that will be used to achieve these goals. A new control framework will be presented that enables lighter, more flexible aircraft to maintain aircraft handling qualities, while preventing the aircraft from exceeding structural load limits. The second part of the talk will give an overview of utility-scale wind turbines and their control. Results of collaboration with Dr. Balas will be presented, including new theory to adaptively control the turbine in the presence of structural modes, with the focus on the application of this theory to a high-fidelity simulation of a wind turbine.

Aircraft height estimation using 2-D radar

CSIR Research Space (South Africa)

Hakl, H

2010-01-01

Full Text Available A method to infer height information from an aircraft tracked with a single 2-D search radar is presented. The method assumes level flight in the target aircraft and a good estimate of the speed of the aircraft. The method yields good results...

Combat aircraft noise

Science.gov (United States)

Sgarbozza, M.; Depitre, A.

1992-04-01

A discussion of the characteristics and the noise levels of combat aircraft and of a transport aircraft in taking off and landing are presented. Some methods of noise reduction are discussed, including the following: operational anti-noise procedures; and concepts of future engines (silent post-combustion and variable cycle). Some measurement results concerning the noise generated in flight at great speeds and low altitude will also be examined. Finally, the protection of the environment of French air bases against noise will be described and the possibilities of regulation examined.

Amphibious Aircraft

Data.gov (United States)

National Aeronautics and Space Administration — A brief self composed research article on Amphibious Aircrafts discussing their use, origin and modern day applications along with their advantages and disadvantages...

AIRCRAFT CONFLICTS RESOLUTION BY COURSE MANEUVERING

Directory of Open Access Journals (Sweden)

В. Харченко

2011-02-01

Full Text Available Enhancement of requirements for air traffic efficiency at increasing of flights intensity determines the necessity of development of new optimization methods for aircraft conflict resolutions. The statement of problem of optimal conflict resolutions at Cooperative Air Traffic Management was done. The method for optimal aircraft conflict  resolution by course maneuvering has been  developed. The method using dynamic programming provides planning of aircraft conflict-free trajectory with minimum length. The decomposition of conflict resolution process on phases and stages, definition of states, controls and recursive  equations for generation of optimal course control program were done. Computer modeling of aircraft conflict resolution by developed method was done

Biotin decorated PLGA nanoparticles containing SN-38 designed for cancer therapy.

Science.gov (United States)

Mehdizadeh, Mozhdeh; Rouhani, Hasti; Sepehri, Nima; Varshochian, Reyhaneh; Ghahremani, Mohammad Hossein; Amini, Mohsen; Gharghabi, Mehdi; Ostad, Seyed Nasser; Atyabi, Fatemeh; Baharian, Azin; Dinarvand, Rassoul

2017-05-01

Active targeted chemotherapy is expected to provide more specific delivery of cytotoxic drugs to the tumor cells and hence reducing the side effects on healthy tissues. Due to the over expression of biotin receptors on cancerous cells as a result of further requirement for rapid proliferations, biotin can be a good candidate as a targeting agent. In this study, biotin decorated PLGA nanoparticles (NPs) containing SN-38 were prepared and in vitro studies were evaluated for their improved anti-cancer properties. In conclusion, biotin targeted PLGA NPs containing SN-38 showed preferential anticancer properties against tumor cells with biotin receptor over expression.

Astronauts Cooper and Conrad prepare cameras during visual acuity tests

Science.gov (United States)

1965-01-01

Astronauts L. Gordon Cooper Jr. (left), command pilot, and Charles Conrad Jr., pilot, the prime crew of the Gemini 5 space flight, prepare their cameras while aboard a C-130 aircraft flying near Laredo. The two astronauts are taking part in a series of visual acuity experiments to aid them in learning to identify known terrestrial features under controlled conditions.

Fast Aircraft Turnaround Enabled by Reliable Passenger Boarding

Directory of Open Access Journals (Sweden)

Michael Schultz

2018-01-01

Full Text Available Future 4D aircraft trajectories demand comprehensive consideration of environmental, economic, and operational constraints, as well as reliable prediction of all aircraft-related processes. Mutual interdependencies between airports result in system-wide, far-reaching effects in the air traffic network (reactionary delays. To comply with airline/airport challenges over the day of operations, a change to an air-to-air perspective is necessary, with a specific focus on the aircraft ground operations as major driver for airline punctuality. Aircraft ground trajectories primarily consists of handling processes at the stand (deboarding, catering, fueling, cleaning, boarding, unloading, loading, which are defined as the aircraft turnaround. Turnaround processes are mainly controlled by ground handling, airport, or airline staff, except the aircraft boarding, which is driven by passengers’ experience and willingness/ability to follow the proposed boarding procedures. This paper provides an overview of the research done in the field of aircraft boarding and introduces a reliable, calibrated, and stochastic aircraft boarding model. The stochastic boarding model is implemented in a simulation environment to evaluate specific boarding scenarios using different boarding strategies and innovative technologies. Furthermore, the potential of a connected aircraft cabin as sensor network is emphasized, which could provide information on the current and future status of the boarding process.

Preparation of quality control samples for its use in the radioimmunoassay de T{sub 3}, T{sub 4} and TSH; Preparacion de muestras de control de calidad para su uso en el radioinmunoanalisis de T{sub 3}, T{sub 4} y TSH

Energy Technology Data Exchange (ETDEWEB)

Lavalley E, C; Delgado S, B; Ruiz J, A; Zambrano A, F

1991-09-15

The use of quality control samples is necessary to evaluate, in a very simple way, the quality of the assays in the radioimmunoanalysis, since allows to settle down a quality control intra and inter analysis. In this work the methodology used for the preparation of these samples with low, media and high concentration for hormones related with the thyroid is shown, being obtained the following concentrations: 50, 200 and 500 ng/dl for T{sub 3}; 5.6, 7.8 and 14.4 {mu} g/dl for T{sub 4} and 5.4, 13.4 and >50 {mu} U I/ml for TSH. (Author)

Preparation, crystallization, and preliminary X-ray diffraction study of mutant carboxypeptidase T containing the primary specificity pocket of carboxypeptidase B

International Nuclear Information System (INIS)

Akparov, V. Kh.; Grishin, A. M.; Timofeev, V. I.; Kuranova, I. P.

2010-01-01

Recombinant G215S, A251G, T257A, D260G, T262D mutant carboxypeptidase T from Thermoactinomyces vulgaris containing mutations in the primary specificity pocket was prepared and crystallized. Single crystals with a size of up to 0.3 mm were grown and investigated by X-ray diffraction. Recombinant mutant carboxypeptidase T containing the primary specificity subsite compositionally identical to that of pancreatic carboxypeptidase B crystallizes in the same space group as the natural enzyme. The crystals belong to sp. gr. P6 3 22; the unit-cell parameters are a = b = 157.867 A, c = 104.304 A, α = β = 90 deg., γ = 120 deg. X-ray diffraction data suitable for determining the three-dimensional structure at atomic resolution were collected from one crystal.

Merenje prelaznih opterećenja na dva modela u aero tunelu t-38 / Measurement of transient loads on two models

Directory of Open Access Journals (Sweden)

Aleksandar Vitić

2008-07-01

Full Text Available Pri ispitivanju modela u "rafalnom" aerotunelu sa prekidnim dejstvom T-38, na Mahovim brojevima većim od 2, moraju se uzeti u obzir prelazne pojave koje se javljaju na početku i na kraju rada aerotunela. To su stanja kada su model i aerovaga izloženi velikim aerodinamičkim silama i momentima. Ova kombinovana opterećenja mogu oštetiti modele i aerovage, pa bi bilo potrebno unapred znati kolike se vrednosti očekuju za pojedine konfiguracije modela, kako bi se izvršio pravilan izbor aerovage i odgovarajućih materijala za izradu modela. U tu svrhu postoje dijagrami koji pružaju mogućnost procene ovih opterećenja. Dijagrami su dobijeni na osnovu ispitivanja nekoliko različitih modela na Mahovim brojevima većim od 2. U radu su prikazana merenja prelaznih opterećenja na još dva modela, a rezultati su upoređeni sa već postojećim dijagramima. / The T-38 wind tunnel is a blow down, intermittent-run type of wind tunnels. During model testing in the this type of wind tunnels, at Mach numbers higher than 2, transient loads which appear during the starting and stopping of the wind tunnel runs must be taken into consideration. These are the conditions when a model and the wind tunnel balance are exposed to large aerodynamic forces and moments. These combined loads can damage models and wind tunnel balances, and, for this reason, it is very important to determine them in advance for any particular model configuration so that an appropriate wind tunnel balance and materials for model manufacturing can be chosen. For that purpose there are graphs which give possibilities to estimate these loads. The graphs are based on experiments with a number of different models at Mach numbers higher than 2. This paper gives the measurements of transient loads on two more models and the results are compared with the already existing graphs.

Aircraft gas turbines

Energy Technology Data Exchange (ETDEWEB)

Sekido, T [Ishikawajima-Harima Heavy Industries, Co. Ltd., Tokyo (Japan)

1994-03-01

Current developmental activities of aircraft gas turbines in Japan are reviewed. V2500-A5 engine with thrust of 30,000 LBF is scheduled to be used for real aircraft in 1994, and intensive developmental activities are also proceeding in larger engines over 90,000 LBF. Recently, developmental programs of engines for 75-100 seat aircraft have been actively discussed, and Japanese engine makers are having discussions towards international collaboration. Such engines will be high bypass turbofans of 12,000-22,000 LBF. Development of SST/HST engines in a speed range from subsonic to Mach 5 is under the initiative of the Agency of Industrial Science and Technology. The Technical Research and Development Institute of Japan, Defence Agency achieved the target thrust of 3.4 tons in the small turbofan engine program, and the small turboshaft engine for small helicopters is also under development. Both National Aerospace Laboratory (NAL) and Institute of Space and Aeronautical Science (ISAS) are now conducting the research programs on turbo-ramjet engines under a component test phase. 1 fig.

14 CFR 47.19 - FAA Aircraft Registry.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false FAA Aircraft Registry. 47.19 Section 47.19... REGISTRATION General § 47.19 FAA Aircraft Registry. Each application, request, notification, or other communication sent to the FAA under this Part must be mailed to the FAA Aircraft Registry, Department of...

Systematic analysis of aircraft separation requirements

Science.gov (United States)

Ennis, Rachelle Lea

2005-12-01

Minimum separation standards are necessary for safety in the air traffic control system. At the same time, minimum separation standards constrain the flow of air traffic and cause delays that translate to millions of dollars in fuel costs. Two necessary separation standards are defined. Then, practical methods for calculating the minimum required size of these separation standards are presented. First, the protected zone is considered. The protected zone represents a region around a given aircraft that no other aircraft should penetrate for the safety of both aircraft. It defines minimum separation requirements. Three major components of the protected zone and their interplays are identified: a vortex region, a safety buffer region, and a state-uncertainty region. A systematic procedure is devised for the analysis of the state-uncertainty region. In particular, models of trajectory controls are developed that can be used to represent different modes of pilot and/or autopilot controls, such as path feedback and non-path feedback. Composite protected zones under various conditions are estimated, and effective ways to reduce sizes of protected zones for advanced air traffic management are examined. In order to maintain minimum separation standards between two aircraft, proper avoidance maneuvers must be initiated before their relative separation reaches the minimum separation due to aircraft dynamics, controller and pilot response delays, etc. The concept of the required action threshold is presented. It is defined as the advanced time for which the conflict resolution process must begin in order to maintain minimum separation requirements. Five main segments in the process of conflict resolution are identified, discussed, and modeled: state information acquisition, comprehension and decision, communication, pilot response, and aircraft maneuver. Each of the five segments is modeled via a time constant. Time estimates for the first four segments are obtained from

14 CFR 43.7 - Persons authorized to approve aircraft, airframes, aircraft engines, propellers, appliances, or...

Science.gov (United States)

2010-01-01

... data approved by the Administrator. (e) The holder of an air carrier operating certificate or an... holder of a repairman certificate (light-sport aircraft) with a maintenance rating may approve an aircraft issued a special airworthiness certificate in light-sport category for return to service, as...

[Effect of lipopolysaccharides extracted from Porphyromonas endodontalis on the expression of p38 and ERK1/2 in osteoblast].

Science.gov (United States)

Lv, You; Jia, Ge; Qiu, Li-hong; Bao, Mu-rong; Yu, Ya-qiong; Guo, Yan

2012-08-01

To investigate the effect of lipopolysaccharides (LPS) extracted from Porphyromonas endodontalis(P.e) on the expression of p38 and ERK1/2 in osteoblast. MC3T3-E1 cells were stimulated with 10 μg/mL P.e-LPS for 0,5,15,30,60,180 min. The phosphorylation of p38 and ERK1/2 was measured by Western blot. Statistical analysis was performed using one- way ANOVA and Dunnett t test with SPSS11.0 software package. 10 μg/mL LPS could significantly activate p38 MAPK. The peak of phosphorylated p38 was detected at 5 to 30 min(P<0.01) and returned to baseline within 60 min; the level of phosphorylated ERK1/2 increased after the stimulation of LPS for 5 min and reached maximum at 15 min (P<0.01) and declined after 30 min. P.e-LPS can induce the expression of p38 and ERK1/2 in osteoblast MC3T3-E1, which indicates that P.e-LPS may play an important role in osteoblast through p38 and ERK1/2.

Future aircraft networks and schedules

Science.gov (United States)

Shu, Yan

2011-07-01

Because of the importance of air transportation scheduling, the emergence of small aircraft and the vision of future fuel-efficient aircraft, this thesis has focused on the study of aircraft scheduling and network design involving multiple types of aircraft and flight services. It develops models and solution algorithms for the schedule design problem and analyzes the computational results. First, based on the current development of small aircraft and on-demand flight services, this thesis expands a business model for integrating on-demand flight services with the traditional scheduled flight services. This thesis proposes a three-step approach to the design of aircraft schedules and networks from scratch under the model. In the first step, both a frequency assignment model for scheduled flights that incorporates a passenger path choice model and a frequency assignment model for on-demand flights that incorporates a passenger mode choice model are created. In the second step, a rough fleet assignment model that determines a set of flight legs, each of which is assigned an aircraft type and a rough departure time is constructed. In the third step, a timetable model that determines an exact departure time for each flight leg is developed. Based on the models proposed in the three steps, this thesis creates schedule design instances that involve almost all the major airports and markets in the United States. The instances of the frequency assignment model created in this thesis are large-scale non-convex mixed-integer programming problems, and this dissertation develops an overall network structure and proposes iterative algorithms for solving these instances. The instances of both the rough fleet assignment model and the timetable model created in this thesis are large-scale mixed-integer programming problems, and this dissertation develops subproblem schemes for solving these instances. Based on these solution algorithms, this dissertation also presents

Review of Aircraft Electric Power Systems and Architectures

DEFF Research Database (Denmark)

Zhao, Xin; Guerrero, Josep M.; Wu, Xiaohao

2014-01-01

In recent years, the electrical power capacity is increasing rapidly in more electric aircraft (MEA), since the conventional mechanical, hydraulic and pneumatic energy systems are partly replaced by electrical power system. As a consequence, capacity and complexity of aircraft electric power...... systems (EPS) will increase dramatically and more advanced aircraft EPSs need to be developed. This paper gives a brief description of the constant frequency (CF) EPS, variable frequency (VF) EPS and advanced high voltage (HV) EPS. Power electronics in the three EPS is overviewed. Keywords: Aircraft Power...... System, More Electric Aircraft, Constant Frequency, Variable Frequency, High Voltage....

77 FR 45979 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

Science.gov (United States)

2012-08-02

... Airworthiness Directives; Piper Aircraft, Inc. Airplanes AGENCY: Federal Aviation Administration (FAA), DOT... (AD) for certain Piper Aircraft, Inc. (type certificate previously held by The New Piper Aircraft Inc... information identified in this proposed AD, contact Piper Aircraft, Inc., 2926 Piper Drive, Vero Beach...

Cosmic Radiation - An Aircraft Manufacturer's View

International Nuclear Information System (INIS)

Hume, C.

1999-01-01

The relevance and context of cosmic radiation to an aircraft maker Airbus Industrie are outlined. Some future developments in aircraft and air traffic are described, along with their possible consequences for exposure. (author)

2002 Industry Studies: Aircraft

Science.gov (United States)

2002-01-01

aircraft to a defense electronics, systems integration and information technology company.39 Northrop Grumman no longer seeks a position as a prime...between the military and civil market . Though also upgrading the H-1 helicopter series for the USMC, Bell has mortgaged its future on tiltrotor technology ...business in export dollars, the industry has been forced to look for new markets as worldwide aircraft sales have dropped. Because the U.S. national

Multifuel rotary aircraft engine

Science.gov (United States)

Jones, C.; Berkowitz, M.

1980-01-01

The broad objectives of this paper are the following: (1) to summarize the Curtiss-Wright design, development and field testing background in the area of rotary aircraft engines; (2) to briefly summarize past activity and update development work in the area of stratified charge rotary combustion engines; and (3) to discuss the development of a high-performance direct injected unthrottled stratified charge rotary combustion aircraft engine. Efficiency improvements through turbocharging are also discussed.

Final Rule for Control of Air Pollution From Aircraft and Aircraft Engines; Emission Standards and Test Procedures

Science.gov (United States)

EPA adopted emission standards and related provisions for aircraft gas turbine engines with rated thrusts greater than 26.7 kilonewtons. These engines are used primarily on commercial passenger and freight aircraft.

Development and experimental characterization of a fuel cell powered aircraft

Energy Technology Data Exchange (ETDEWEB)

Bradley, Thomas H.; Moffitt, Blake A.; Mavris, Dimitri N.; Parekh, David E. [Georgia Institute of Technology, Atlanta, GA 30332-0405 (United States)

2007-09-27

This paper describes the characteristics and performance of a fuel cell powered unmanned aircraft. The aircraft is novel as it is the largest compressed hydrogen fuel cell powered airplane built to date and is currently the only fuel cell aircraft whose design and test results are in the public domain. The aircraft features a 500 W polymer electrolyte membrane fuel cell with full balance of plant and compressed hydrogen storage incorporated into a custom airframe. Details regarding the design requirements, implementation and control of the aircraft are presented for each major aircraft system. The performances of the aircraft and powerplant are analyzed using data from flights and laboratory tests. The efficiency and component power consumption of the fuel cell propulsion system are measured at a variety of flight conditions. The performance of the aircraft powerplant is compared to other 0.5-1 kW-scale fuel cell powerplants in the literature and means of performance improvement for this aircraft are proposed. This work represents one of the first studies of fuel cell powered aircraft to result in a demonstration aircraft. As such, the results of this study are of practical interest to fuel cell powerplant and aircraft designers. (author)

STS-38 crewmembers eat meal on OV-104's middeck

Science.gov (United States)

1990-01-01

STS-38 Pilot Frank L. Culbertson, holding spoon to his mouth, prepares to take a bite of food. Mission Specialist (MS) Charles D. Gemar licks his upper lip in anticipation of his next bite. The two crewmembers are on the middeck of Atlantis, Orbiter Vehicle (OV) 104, while enjoying their meal. Behind them are the starboard wall-mounted sleep restraints.

Challenges of future aircraft propulsion: A review of distributed propulsion technology and its potential application for the all electric commercial aircraft

Science.gov (United States)

Gohardani, Amir S.; Doulgeris, Georgios; Singh, Riti

2011-07-01

This paper highlights the role of distributed propulsion technology for future commercial aircraft. After an initial historical perspective on the conceptual aspects of distributed propulsion technology and a glimpse at numerous aircraft that have taken distributed propulsion technology to flight, the focal point of the review is shifted towards a potential role this technology may entail for future commercial aircraft. Technological limitations and challenges of this specific technology are also considered in combination with an all electric aircraft concept, as means of predicting the challenges associated with the design process of a next generation commercial aircraft.

36 CFR 331.14 - Aircraft.

Science.gov (United States)

2010-07-01

... GOVERNING THE PROTECTION, USE AND MANAGEMENT OF THE FALLS OF THE OHIO NATIONAL WILDLIFE CONSERVATION AREA, KENTUCKY AND INDIANA § 331.14 Aircraft. (a) The operation of aircraft on WCA lands and waters is prohibited... business of the Federal Government or used in emergency rescue in accordance with the directions of the...

ERGONOMIC DESIGN OF AIRCRAFT COCKPIT

Directory of Open Access Journals (Sweden)

CÎMPIAN Ionuţ

2012-09-01

Full Text Available This paper presents a model for an ergonomic design of an aircraft cockpit with the specification and verification with respect to the new European Aviation Safety Agency (EASA and Federal Aviation Administration (FAA requirements. The goal is to expressing the concepts on which the aircraft cockpit design are based.

ERGONOMIC DESIGN OF AIRCRAFT COCKPIT

Directory of Open Access Journals (Sweden)

CÎMPIAN Ionuţ

2011-06-01

Full Text Available This paper presents a model for an ergonomic design of an aircraft cockpit with the specification and verification with respect to the new European Aviation Safety Agency (EASA and Federal Aviation Administration (FAA requirements. The goal is to expressing the concepts on which the aircraft cockpit design is based.

Air-sampling inlet contamination by aircraft emissions on the NASA CV-990 aircraft

Science.gov (United States)

Condon, E. P.; Vedder, J. F.

1984-01-01

Results of an experimental investigation of the contamination of air sampling inlets by aircraft emissions from the NASA CV-990 research aircraft are presented. This four-engine jet aircraft is a NASA facility used for many different atmospheric and meteorological experiments, as well as for developing spacecraft instrumentation for remote measurements. Our investigations were performed to provide information on which to base the selection of sampling locations for a series of multi-instrument missions for measuring tropospheric trace gases. The major source of contamination is the exhaust from the jet engines, which generate many of the same gases that are of interest in atmospheric chemistry, as well as other gases that may interfere with sampling measurements. The engine exhaust contains these gases in mixing ratios many orders of magnitude greater than those that occur in the clean atmosphere which the missions seek to quantify. Pressurized samples of air were collected simultaneously from a scoop located forward of the engines to represent clean air and from other multiport scoops at various aft positions on the aircraft. The air samples were analyzed in the laboratory by gas chromatography for carbon monoxide, an abundant combustion by-product. Data are presented for various scoop locations under various flight conditions.

Modeling Programs Increase Aircraft Design Safety

Science.gov (United States)

2012-01-01

Flutter may sound like a benign word when associated with a flag in a breeze, a butterfly, or seaweed in an ocean current. When used in the context of aerodynamics, however, it describes a highly dangerous, potentially deadly condition. Consider the case of the Lockheed L-188 Electra Turboprop, an airliner that first took to the skies in 1957. Two years later, an Electra plummeted to the ground en route from Houston to Dallas. Within another year, a second Electra crashed. In both cases, all crew and passengers died. Lockheed engineers were at a loss as to why the planes wings were tearing off in midair. For an answer, the company turned to NASA s Transonic Dynamics Tunnel (TDT) at Langley Research Center. At the time, the newly renovated wind tunnel offered engineers the capability of testing aeroelastic qualities in aircraft flying at transonic speeds near or just below the speed of sound. (Aeroelasticity is the interaction between aerodynamic forces and the structural dynamics of an aircraft or other structure.) Through round-the-clock testing in the TDT, NASA and industry researchers discovered the cause: flutter. Flutter occurs when aerodynamic forces acting on a wing cause it to vibrate. As the aircraft moves faster, certain conditions can cause that vibration to multiply and feed off itself, building to greater amplitudes until the flutter causes severe damage or even the destruction of the aircraft. Flutter can impact other structures as well. Famous film footage of the Tacoma Narrows Bridge in Washington in 1940 shows the main span of the bridge collapsing after strong winds generated powerful flutter forces. In the Electra s case, faulty engine mounts allowed a type of flutter known as whirl flutter, generated by the spinning propellers, to transfer to the wings, causing them to vibrate violently enough to tear off. Thanks to the NASA testing, Lockheed was able to correct the Electra s design flaws that led to the flutter conditions and return the

Technology for reducing aircraft engine pollution

Science.gov (United States)

Rudey, R. A.; Kempke, E. E., Jr.

1975-01-01

Programs have been initiated by NASA to develop and demonstrate advanced technology for reducing aircraft gas turbine and piston engine pollutant emissions. These programs encompass engines currently in use for a wide variety of aircraft from widebody-jets to general aviation. Emission goals for these programs are consistent with the established EPA standards. Full-scale engine demonstrations of the most promising pollutant reduction techniques are planned within the next three years. Preliminary tests of advanced technology gas turbine engine combustors indicate that significant reductions in all major pollutant emissions should be attainable in present generation aircraft engines without adverse effects on fuel consumption. Fundamental-type programs are yielding results which indicate that future generation gas turbine aircraft engines may be able to utilize extremely low pollutant emission combustion systems.

Maintenance program developmentandImport /Export of Aircraft in USA

OpenAIRE

Takele, Teklu

2009-01-01

AbstractThis thesis discuss how United Parcel Service (UPS) develop its aircraft maintenanceprogram after import of McDonnell Douglas MD-11aircraft and the process of exporting newMD-11 aircraft from manufacturer in USA to European operator as passenger aircraft. It alsodiscusses the process of importing the same types of aircraft as freight carrier. The aircraftundergo, through different modifications at Singapore Technologies Aerospace (STA)conversion from passenger to freight carrier, a pr...

Defense Strategy of Aircraft Confronted with IR Guided Missile

Directory of Open Access Journals (Sweden)

Hesong Huang

2017-01-01

Full Text Available Surface-type infrared (IR decoy can simulate the IR characteristics of the target aircraft, which is one of the most effective equipment to confront IR guided missile. In the air combat, the IR guided missile poses a serious threat to the aircraft when it comes from the front of target aircraft. In this paper, firstly, the model of aircraft and surface-type IR decoy is established. To ensure their authenticity, the aircraft maneuver and radiation models based on real data of flight and exhaust system radiation in the state of different heights and different speeds are established. Secondly, the most effective avoidance maneuver is simulated when the missile comes from the front of the target aircraft. Lastly, combining maneuver with decoys, the best defense strategy is analysed when the missile comes from the front of aircraft. The result of simulation, which is authentic, is propitious to avoid the missile and improve the survivability of aircraft.

Live Aircraft Encounter Visualization at FutureFlight Central

Science.gov (United States)

Murphy, James R.; Chinn, Fay; Monheim, Spencer; Otto, Neil; Kato, Kenji; Archdeacon, John

2018-01-01

Researchers at the National Aeronautics and Space Administration (NASA) have developed an aircraft data streaming capability that can be used to visualize live aircraft in near real-time. During a joint Federal Aviation Administration (FAA)/NASA Airborne Collision Avoidance System flight series, test sorties between unmanned aircraft and manned intruder aircraft were shown in real-time at NASA Ames' FutureFlight Central tower facility as a virtual representation of the encounter. This capability leveraged existing live surveillance, video, and audio data streams distributed through a Live, Virtual, Constructive test environment, then depicted the encounter from the point of view of any aircraft in the system showing the proximity of the other aircraft. For the demonstration, position report data were sent to the ground from on-board sensors on the unmanned aircraft. The point of view can be change dynamically, allowing encounters from all angles to be observed. Visualizing the encounters in real-time provides a safe and effective method for observation of live flight testing and a strong alternative to travel to the remote test range.

Fuel characteristics pertinent to the design of aircraft fuel systems

Science.gov (United States)

Barnett, Henry C; Hibbard, R R

1953-01-01

Because of the importance of fuel properties in design of aircraft fuel systems the present report has been prepared to provide information on the characteristics of current jet fuels. In addition to information on fuel properties, discussions are presented on fuel specifications, the variations among fuels supplied under a given specification, fuel composition, and the pertinence of fuel composition and physical properties to fuel system design. In some instances the influence of variables such as pressure and temperature on physical properties is indicated. References are cited to provide fuel system designers with sources of information containing more detail than is practicable in the present report.

77 FR 70114 - Airworthiness Directives; Cessna Aircraft Company Airplanes

Science.gov (United States)

2012-11-23

... Aircraft Company Service Bulletin SB04-28-03, dated August 30, 2004, and Engine Fuel Return System... Aircraft System Component (JASC)/Air Transport Association (ATA) of America Code 2820, Aircraft Fuel... Modification Do not incorporate Cessna Aircraft Company Engine Fuel Return System Modification Kit MK 172-28-01...

Modeling of aircraft exhaust emissions and infrared spectra for remote measurement of nitrogen oxides

Directory of Open Access Journals (Sweden)

K. Beier

1994-08-01

Full Text Available Infrared (IR molecular spectroscopy is proposed to perform remote measurements of NOx concentrations in the exhaust plume and wake of aircraft. The computer model NIRATAM is applied to simulate the physical and chemical properties of the exhaust plume and to generate low resolution IR spectra and synthetical thermal images of the aircraft in its natural surroundings. High-resolution IR spectra of the plume, including atmospheric absorption and emission, are simulated using the molecular line-by-line radiation model FASCODE2. Simulated IR spectra of a Boeing 747-400 at cruising altitude for different axial and radial positions in the jet region of the exhaust plume are presented. A number of spectral lines of NO can be identified that can be discriminated from lines of other exhaust gases and the natural atmospheric background in the region around 5.2 µm. These lines can be used to determine NO concentration profiles in the plume. The possibility of measuring nitrogen dioxide NO2 is also discussed briefly, although measurements turn out to be substantially less likely than those of NO. This feasibility study compiles fundamental data for the optical and radiometric design of an airborne Fourier transform spectrometer and the preparation of in-flight measurements for monitoring of aircraft pollutants.

Modeling of aircraft exhaust emissions and infrared spectra for remote measurement of nitrogen oxides

Directory of Open Access Journals (Sweden)

K. Beier

Full Text Available Infrared (IR molecular spectroscopy is proposed to perform remote measurements of NO_x concentrations in the exhaust plume and wake of aircraft. The computer model NIRATAM is applied to simulate the physical and chemical properties of the exhaust plume and to generate low resolution IR spectra and synthetical thermal images of the aircraft in its natural surroundings. High-resolution IR spectra of the plume, including atmospheric absorption and emission, are simulated using the molecular line-by-line radiation model FASCODE2. Simulated IR spectra of a Boeing 747-400 at cruising altitude for different axial and radial positions in the jet region of the exhaust plume are presented. A number of spectral lines of NO can be identified that can be discriminated from lines of other exhaust gases and the natural atmospheric background in the region around 5.2 µm. These lines can be used to determine NO concentration profiles in the plume. The possibility of measuring nitrogen dioxide NO₂ is also discussed briefly, although measurements turn out to be substantially less likely than those of NO. This feasibility study compiles fundamental data for the optical and radiometric design of an airborne Fourier transform spectrometer and the preparation of in-flight measurements for monitoring of aircraft pollutants.

V/STOL tilt rotor aircraft study. Volume 6: Preliminary design of a composite wing for tilt rotor research aircraft

Science.gov (United States)

Soule, V. A.; Badri-Nath, Y.

1973-01-01

The results of a study of the use of composite materials in the wing of a tilt rotor aircraft are presented. An all-metal tilt rotor aircraft was first defined to provide a basis for comparing composite with metal structure. A configuration study was then done in which the wing of the metal aircraft was replaced with composite wings of varying chord and thickness ratio. The results of this study defined the design and performance benefits obtainable with composite materials. Based on these results the aircraft was resized with a composite wing to extend the weight savings to other parts of the aircraft. A wing design was then selected for detailed structural analysis. A development plan including costs and schedules to develop this wing and incorporate it into a proposed flight research tilt rotor vehicle has been devised.

Scheduling Aircraft Landings under Constrained Position Shifting

Science.gov (United States)

Balakrishnan, Hamsa; Chandran, Bala

2006-01-01

Optimal scheduling of airport runway operations can play an important role in improving the safety and efficiency of the National Airspace System (NAS). Methods that compute the optimal landing sequence and landing times of aircraft must accommodate practical issues that affect the implementation of the schedule. One such practical consideration, known as Constrained Position Shifting (CPS), is the restriction that each aircraft must land within a pre-specified number of positions of its place in the First-Come-First-Served (FCFS) sequence. We consider the problem of scheduling landings of aircraft in a CPS environment in order to maximize runway throughput (minimize the completion time of the landing sequence), subject to operational constraints such as FAA-specified minimum inter-arrival spacing restrictions, precedence relationships among aircraft that arise either from airline preferences or air traffic control procedures that prevent overtaking, and time windows (representing possible control actions) during which each aircraft landing can occur. We present a Dynamic Programming-based approach that scales linearly in the number of aircraft, and describe our computational experience with a prototype implementation on realistic data for Denver International Airport.

A homologous series of homoleptic zinc bis(1,4-di-tert-butyl-1,4-diaza-1,3-butadiene) complexes: Kx[Zn(t-BuNCHCHN-t-Bu)2], Zn(t-BuNCHCHN-t-Bu)2, and [Zn(t-BuNCHCHN-t-Bu)2](OTf)x)(X=1,2)

NARCIS (Netherlands)

Koten, G. van; Rijnberg, E.; Richter, B.; Thiele, K.-H.; Boersma, J.; Veldman, N.; Spek, A.L.

1998-01-01

A homologous series of mono- and dicationic, neutral, and mono- and dianionic zinc diazabutadiene complexes, Kx[Zn(t-BuNCHCHN-t-Bu)2], Zn(t-BuNCHCHN-t-Bu)2, and [Zn(t-BuNCHCHN-t-Bu)2](OTf)x (x = 1, 2), have been prepared and isolated in pure form. The crystal structures of the mono- and dicationic

FAA-NASA Sixth International Conference on the Continued Airworthiness of Aircraft Structures

Science.gov (United States)

1995-12-01

Administration, and Colin G. Drury , State University of New York at Buffalo The Aging Aircraft Nondestructive Inspection Validation Center - A R esource for...William T. Shepherd FAA-Office of Aviation Medicine Washington, DC and Colin G. Drury State University of New York at Buffalo Buffalo, NY INTRODUCTION FAA’s...improvement, changing the task, the operator (inspector), machine, or environment as appropriate, e.g., review in Drury , 1992 (Ref. 1). 2. From the

Prognostic investigation of galvanic corrosion precursors in aircraft structures and their detection strategy

Science.gov (United States)

James, Robin; Kim, Tae Hee; Narayanan, Ram M.

2017-04-01

Aluminum alloys have been the dominant materials for aerospace construction in the past fifty years due to their light weight, forming and alloying, and relative low cost in comparison to titanium and composites. However, in recent years, carbon fiber reinforced polymers (CFRPs) and honeycomb materials have been used in aircrafts in the quest to attain lower weight, high temperature resistance, and better fuel efficiency. When these two materials are coupled together, the structural strength of the aircraft is unparalleled, but this comes at a price, namely galvanic corrosion. Previous experimental results have shown that when CFRP composite materials are joined with high strength aluminum alloys (AA7075-T6 or AA2024-T3), galvanic corrosion occurs at the material interfaces, and the aluminum is in greater danger of corroding, particularly since carbon and aluminum are on the opposite ends of the galvanic series. In this paper, we explore the occurrence of the recognizable precursors of galvanic corrosion when CFRP plate is coupled to an aluminum alloy using SS-304 bolts and exposed to environmental degradation, which creates significant concerns for aircraft structural reliability. The galvanic corrosion software package, BEASY, is used to simulate the growth of corrosion in the designed specimen after which a microwave non-destructive testing (NDT) technique is explored to detect corrosion defects that appear at the interface of this galvanic couple. This paper also explores a loaded waveguide technique to determine the dielectric constant of the final corrosion product at the Q-band millimeter-wave frequency range (33-50 GHz), as this can be an invaluable asset in developing early detection strategies.

AIRCRAFT MAINTENANCE HANGAR

Directory of Open Access Journals (Sweden)

GEAMBASU Gabriel George

2017-05-01

Full Text Available The paper presents the maintenance process that is done on an airplane, at a certain period of time, or after a number of flight hours or cycles and describes the checks performed behind each inspection. The first part of research describes the aircraft maintenance process that has to be done after an updated maintenance manual according with aircraft type, followed by a short introduction about maintenance hangar. The second part of the paper presents a hangar design with a foldable roof and walls, which can be folded or extended, over an airplane when a maintenance process is done, or depending on weather condition.

Airfoil optimization for morphing aircraft

Science.gov (United States)

Namgoong, Howoong

Continuous variation of the aircraft wing shape to improve aerodynamic performance over a wide range of flight conditions is one of the objectives of morphing aircraft design efforts. This is being pursued because of the development of new materials and actuation systems that might allow this shape change. The main purpose of this research is to establish appropriate problem formulations and optimization strategies to design an airfoil for morphing aircraft that include the energy required for shape change. A morphing aircraft can deform its wing shape, so the aircraft wing has different optimum shapes as the flight condition changes. The actuation energy needed for moving the airfoil surface is modeled and used as another design objective. Several multi-objective approaches are applied to a low-speed, incompressible flow problem and to a problem involving low-speed and transonic flow. The resulting solutions provide the best tradeoff between low drag, high energy and higher drag, low energy sets of airfoil shapes. From this range of solutions, design decisions can be made about how much energy is needed to achieve a desired aerodynamic performance. Additionally, an approach to model aerodynamic work, which would be more realistic and may allow using pressure on the airfoil to assist a morphing shape change, was formulated and used as part of the energy objective. These results suggest that it may be possible to design a morphing airfoil that exploits the airflow to reduce actuator energy.

3.8 Proposed approach to uncertainty quantification and sensitivity analysis in the next PA

Energy Technology Data Exchange (ETDEWEB)

Flach, Greg [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Wohlwend, Jen [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2017-10-02

This memorandum builds upon Section 3.8 of SRNL (2016) and Flach (2017) by defining key error analysis, uncertainty quantification, and sensitivity analysis concepts and terms, in preparation for the next E-Area Performance Assessment (WSRC 2008) revision.

76 FR 71081 - Public Aircraft Oversight Safety Forum

Science.gov (United States)

2011-11-16

... NATIONAL TRANSPORTATION SAFETY BOARD Public Aircraft Oversight Safety Forum The National Transportation Safety Board (NTSB) will convene a Public Aircraft Oversight Safety Forum which will begin at 9 a... ``Public Aircraft Oversight Forum: Ensuring Safety for Critical Missions'', are to (1) raise awareness of...

Low-Field NMR Spectrometry of Chalk and Argillaceous Sandstones: Rock-Fluid Affinity Assessed from T-1/T-2 Ratio

DEFF Research Database (Denmark)

Katika, Konstantina; Saidian, Milad; Prasad, Manika

2017-01-01

greensand shows different behavior for small and large pores. Small pores (fast-relaxing components) have T-1/T-2 = 2.0 when water saturated, but T-1/T-2 = 3.8 when oil saturated, indicating oil-affinity of chlorite. By contrast, large pores (slow-relaxing components) have significant preference for water...

An Overview of NASA's Subsonic Research Aircraft Testbed (SCRAT)

Science.gov (United States)

Baumann, Ethan; Hernandez, Joe; Ruhf, John C.

2013-01-01

National Aeronautics and Space Administration Dryden Flight Research Center acquired a Gulfstream III (GIII) aircraft to serve as a testbed for aeronautics flight research experiments. The aircraft is referred to as SCRAT, which stands for SubsoniC Research Aircraft Testbed. The aircraft's mission is to perform aeronautics research; more specifically raising the Technology Readiness Level (TRL) of advanced technologies through flight demonstrations and gathering high-quality research data suitable for verifying the technologies, and validating design and analysis tools. The SCRAT has the ability to conduct a range of flight research experiments throughout a transport class aircraft's flight envelope. Experiments ranging from flight-testing of a new aircraft system or sensor to those requiring structural and aerodynamic modifications to the aircraft can be accomplished. The aircraft has been modified to include an instrumentation system and sensors necessary to conduct flight research experiments along with a telemetry capability. An instrumentation power distribution system was installed to accommodate the instrumentation system and future experiments. An engineering simulation of the SCRAT has been developed to aid in integrating research experiments. A series of baseline aircraft characterization flights has been flown that gathered flight data to aid in developing and integrating future research experiments. This paper describes the SCRAT's research systems and capabilities.

78 FR 7642 - Airworthiness Directives; Piper Aircraft, Inc.

Science.gov (United States)

2013-02-04

... Airworthiness Directives; Piper Aircraft, Inc. AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for certain Piper Aircraft, Inc. (type certificate previously held by The New Piper Aircraft Inc.) PA-28, PA-32, PA-34, and PA-44...

Fault Diagnosis and Fault Handling for Autonomous Aircraft

DEFF Research Database (Denmark)

Hansen, Søren

Unmanned Aerial vehicles (UAVs) or drones are used increasingly for missions where piloted aircraft are unsuitable. The unmanned aircraft has a number of advantages with respect to size, weight and manoeuvrability that makes it possible for them to solve tasks that an aircraft previously has been...

Intensive probing of a clear air convective field by radar and instrumental drone aircraft.

Science.gov (United States)

Rowland, J. R.

1973-01-01

An instrumented drone aircraft was used in conjunction with ultrasensitive radar to study the development of a convective field in the clear air. Radar data are presented which show an initial constant growth rate in the height of the convective field of 3.8 m/min, followed by a short period marked by condensation and rapid growth at a rate in excess of 6.1 m/min. Drone aircraft soundings show general features of a convective field including progressive lifting of the inversion at the top of the convection and a cooling of the air at the top of the field. Calculations of vertical heat flux as a function of time and altitude during the early stages of convection show a linear decrease in heat flux with altitude to near the top of the convective field and a negative heat flux at the top. Evidence is presented which supports previous observations that convective cells overshoot their neutral buoyancy level into a region where they are cool and moist compared to their surroundings. Furthermore, only that portion of the convective cell that has overshot its neutral buoyancy level is generally visible to the radar.

Aircraft Noise and Quality of Life around Frankfurt Airport

Directory of Open Access Journals (Sweden)

Thomas Eikmann

2010-08-01

Full Text Available In a survey of 2,312 residents living near Frankfurt Airport aircraft noise annoyance and disturbances as well as environmental (EQoL and health-related quality of life (HQoL were assessed and compared with data on exposure due to aircraft, road traffic, and railway noise. Results indicate higher noise annoyance than predicted from general exposure-response curves. Beside aircraft sound levels source-related attitudes were associated with reactions to aircraft noise. Furthermore, aircraft noise affected EQoL in general, although to a much smaller extent. HQoL was associated with aircraft noise annoyance, noise sensitivity and partly with aircraft noise exposure, in particular in the subgroup of multimorbid residents. The results suggest a recursive relationship between noise and health, yet this cannot be tested in cross-sectional studies. Longitudinal studies would be recommendable to get more insight in the causal paths underlying the noise-health relationship.

Durability of aircraft composite materials

Science.gov (United States)

Dextern, H. B.

1982-01-01

Confidence in the long term durability of advanced composites is developed through a series of flight service programs. Service experience is obtained by installing secondary and primary composite components on commercial and military transport aircraft and helicopters. Included are spoilers, rudders, elevators, ailerons, fairings and wing boxes on transport aircraft and doors, fairings, tail rotors, vertical fins, and horizontal stabilizers on helicopters. Materials included in the evaluation are boron/epoxy, Kevlar/epoxy, graphite/epoxy and boron/aluminum. Inspection, maintenance, and repair results for the components in service are reported. The effects of long term exposure to laboratory, flight, and outdoor environmental conditions are reported for various composite materials. Included are effects of moisture absorption, ultraviolet radiation, and aircraft fuels and fluids.

Aircraft cybernetics

Science.gov (United States)

1977-01-01

The use of computers for aircraft control, flight simulation, and inertial navigation is explored. The man-machine relation problem in aviation is addressed. Simple and self-adapting autopilots are described and the assets and liabilities of digital navigation techniques are assessed.

AIRTV: Broadband Direct to Aircraft

Science.gov (United States)

Sorbello, R.; Stone, R.; Bennett, S. B.; Bertenyi, E.

2002-01-01

Airlines have been continuously upgrading their wide-body, long-haul aircraft with IFE (in-flight entertainment) systems that can support from 12 to 24 channels of video entertainment as well as provide the infrastructure to enable in-seat delivery of email and internet services. This is a direct consequence of increased passenger demands for improved in-flight services along with the expectations that broadband delivery systems capable of providing live entertainment (news, sports, financial information, etc.) and high speed data delivery will soon be available. The recent events of Sept. 11 have slowed the airline's upgrade of their IFE systems, but have also highlighted the compelling need for broadband aeronautical delivery systems to include operational and safety information. Despite the impact of these events, it is estimated that by 2005 more than 3000 long haul aircraft (servicing approximately 1 billion passengers annually) will be fully equipped with modern IFE systems. Current aircraft data delivery systems, which use either Inmarsat or NATS, are lacking in bandwidth and consequently are unsuitable to satisfy passenger demands for broadband email/internet services or the airlines' burgeoning data requirements. Present live video delivery services are limited to regional coverage and are not readily expandable to global or multiregional service. Faced with a compelling market demand for high data transport to aircraft, AirTV has been developing a broadband delivery system that will meet both passengers' and airlines' needs. AirTV is a global content delivery system designed to provide a range of video programming and data services to commercial airlines. When AirTV is operational in 2004, it will provide a broadband connection directly to the aircraft, delivering live video entertainment, internet/email service and essential operational and safety data. The system has been designed to provide seamless global service to all airline routes except for those

In Preparation of the Nationwide Dissemination of the School-Based Obesity Prevention Program DOiT: Stepwise Development Applying the Intervention Mapping Protocol

NARCIS (Netherlands)

van Nassau, F.; Singh, A.S.; van Mechelen, W.; Brug, J.; Chin A Paw, M.J.M.

2014-01-01

BACKGROUND: The school-based Dutch Obesity Intervention in Teenagers (DOiT) program is an evidence-based obesity prevention program. In preparation for dissemination throughout the Netherlands, this study aimed to adapt the initial program and to develop an implementation strategy and materials.

78 FR 68985 - Special Conditions: Boeing Model 777-200, -300, and -300ER Series Airplanes; Aircraft Electronic...

Science.gov (United States)

2013-11-18

... Boeing Company applied for a change to Type Certificate No. T00001SE Rev. 30 dated June 6, 2012 for... integration may result in security vulnerabilities from intentional or unintentional corruption of data and... material did not anticipate this type of system architecture or electronic access to aircraft systems...

Knowledge-based scheduling of arrival aircraft

Science.gov (United States)

Krzeczowski, K.; Davis, T.; Erzberger, H.; Lev-Ram, I.; Bergh, C.

1995-01-01

A knowledge-based method for scheduling arrival aircraft in the terminal area has been implemented and tested in real-time simulation. The scheduling system automatically sequences, assigns landing times, and assigns runways to arrival aircraft by utilizing continuous updates of aircraft radar data and controller inputs. The scheduling algorithms is driven by a knowledge base which was obtained in over two thousand hours of controller-in-the-loop real-time simulation. The knowledge base contains a series of hierarchical 'rules' and decision logic that examines both performance criteria, such as delay reduction, as well as workload reduction criteria, such as conflict avoidance. The objective of the algorithms is to devise an efficient plan to land the aircraft in a manner acceptable to the air traffic controllers. This paper will describe the scheduling algorithms, give examples of their use, and present data regarding their potential benefits to the air traffic system.

Future V/STOL Aircraft For The Pacific Basin

Science.gov (United States)

Albers, James A.; Zuk, John

1992-01-01

Report describes geography and transportation needs of Asian Pacific region, and describes aircraft configurations suitable for region and compares performances. Examines applications of high-speed rotorcraft, vertical/short-takeoff-and-landing (V/STOL) aircraft, and short-takeoff-and landing (STOL) aircraft. Configurations benefit commerce, tourism, and development of resources.

31 CFR 538.519 - Aircraft and maritime safety.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Aircraft and maritime safety. 538.519..., Authorizations, and Statements of Licensing Policy § 538.519 Aircraft and maritime safety. Specific licenses may... aircraft, and to ensure the safety of ocean-going maritime traffic in international waters. ...

48 CFR 1852.228-71 - Aircraft flight risks.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Aircraft flight risks. 1852... 1852.228-71 Aircraft flight risks. (a) As prescribed in 1828.311-2, insert the following clause: Aircraft Flight Risks (DEC 1988) (a) Notwithstanding any other provision of this contract (particularly...

Alternative general-aircraft engines

Science.gov (United States)

Tomazic, W. A.

1976-01-01

The most promising alternative engine (or engines) for application to general aircraft in the post-1985 time period was defined, and the level of technology was cited to the point where confident development of a new engine can begin early in the 1980's. Low emissions, multifuel capability, and fuel economy were emphasized. Six alternative propulsion concepts were considered to be viable candidates for future general-aircraft application: the advanced spark-ignition piston, rotary combustion, two- and four-stroke diesel, Stirling, and gas turbine engines.

Hidden corrosion detection in aircraft aluminum structures using laser ultrasonics and wavelet transform signal analysis.

Science.gov (United States)

Silva, M Z; Gouyon, R; Lepoutre, F

2003-06-01

Preliminary results of hidden corrosion detection in aircraft aluminum structures using a noncontact laser based ultrasonic technique are presented. A short laser pulse focused to a line spot is used as a broadband source of ultrasonic guided waves in an aluminum 2024 sample cut from an aircraft structure and prepared with artificially corroded circular areas on its back surface. The out of plane surface displacements produced by the propagating ultrasonic waves were detected with a heterodyne Mach-Zehnder interferometer. Time-frequency analysis of the signals using a continuous wavelet transform allowed the identification of the generated Lamb modes by comparison with the calculated dispersion curves. The presence of back surface corrosion was detected by noting the loss of the S(1) mode near its cutoff frequency. This method is applicable to fast scanning inspection techniques and it is particularly suited for early corrosion detection.

Preparation and characterization of clay bonded high strength silica refractory by utilizing agriculture waste

Directory of Open Access Journals (Sweden)

Aman Bhardwaj

2017-11-01

Full Text Available Clay bonded silica refractory was prepared by utilizing agriculture waste called rice husk ash (RHA and refractory grog. Various samples were prepared with different compositions based upon partial replacement of quartz by RHA. Rectangular samples were prepared by following semi dry process prior to pressing in a uniaxial hydraulic press and sintering at a temperature of 1200 °C in air atmosphere. Various physical, mechanical and thermal characterizations were done like X-ray diffraction (XRD, scanning electron microscope (SEM, apparent porosity (AP, bulk density (BD, cold crushing strength (CCS, refractoriness and thermal conductivity measurement. The sample utilizing 30% of RHA was considered most optimum composition which produced cold crushing strength of 38 MPa and thermal conductivity of 2.08 W/m K at 800 °C with a considerable good refractoriness. Enhancement in the mechanical as well as thermal properties may be considered as attributed to the amorphous silica which has reacted more easily and efficiently with other material surrounding giving rise to the densification and produced stable crystalline phase to the refractory material. These promising characteristics suggests that the RHA may lead to be used as a potential material for the preparation of clay bonded high strength silica refractories. Resumen: Se preparó sílice refractaria unida a arcilla con residuos agrícolas conocidos como ceniza de cascarilla de arroz (rice husk ash [RHA] y grog refractario. Se prepararon varias muestras con diferentes composiciones basadas en la sustitución parcial de cuarzo por RHA. Las muestras rectangulares se prepararon siguiendo un proceso semiseco antes de prensarlas en una prensa hidráulica uniaxial y sinterizarlas a una temperatura de 1.200 °C en atmósfera de aire. Se realizaron diversas caracterizaciones físicas, mecánicas y térmicas, como la difracción de rayos X, el microscopio electrónico de barrido, la porosidad

T-cell receptor transfer into human T cells with ecotropic retroviral vectors.

Science.gov (United States)

Koste, L; Beissert, T; Hoff, H; Pretsch, L; Türeci, Ö; Sahin, U

2014-05-01

Adoptive T-cell transfer for cancer immunotherapy requires genetic modification of T cells with recombinant T-cell receptors (TCRs). Amphotropic retroviral vectors (RVs) used for TCR transduction for this purpose are considered safe in principle. Despite this, TCR-coding and packaging vectors could theoretically recombine to produce replication competent vectors (RCVs), and transduced T-cell preparations must be proven free of RCV. To eliminate the need for RCV testing, we transduced human T cells with ecotropic RVs so potential RCV would be non-infectious for human cells. We show that transfection of synthetic messenger RNA encoding murine cationic amino-acid transporter 1 (mCAT-1), the receptor for murine retroviruses, enables efficient transient ecotropic transduction of human T cells. mCAT-1-dependent transduction was more efficient than amphotropic transduction performed in parallel, and preferentially targeted naive T cells. Moreover, we demonstrate that ecotropic TCR transduction results in antigen-specific restimulation of primary human T cells. Thus, ecotropic RVs represent a versatile, safe and potent tool to prepare T cells for the adoptive transfer.

Aircraft accident analysis for emergency planning and safety analysis

International Nuclear Information System (INIS)

Nicolosi, S.L.; Jordan, H.; Foti, D.; Mancuso, J.

1996-01-01

Potential aircraft accidents involving facilities at the Rocky Flats Environmental Technology Site (Site) are evaluated to assess their safety significance. This study addresses the probability and facility penetrability of aircraft accidents at the Site. The types of aircraft (large, small, etc.) that may credibly impact the Site determine the types of facilities that may be breached. The methodology used in this analysis follows elements of the draft Department of Energy Standard ''Accident Analysis for Aircraft Crash into Hazardous Facilities'' (July 1995). Key elements used are: the four-factor frequency equation for aircraft accidents; the distance criteria for consideration of airports, airways, and jet routes; the consideration of different types of aircraft; and the Modified National Defense Research Committee (NDRC) formula for projectile penetration, perforation, and minimum resistant thickness. The potential aircraft accident frequency for each type of aircraft applicable to the Site is estimated using a four-factor formula described in the draft Standard. The accident frequency is the product of the annual number of operations, probability of an accident, probability density function, and area. The annual number of operations is developed from site-specific and state-wide data

Aircraft engines. IV

Energy Technology Data Exchange (ETDEWEB)

Ruffles, P C

1989-01-01

Configurational design and thermodynamic performance gain trends are projected into the next 50 years, in view of the growing interest of aircraft manufacturers in both larger and more efficient high-bypass turbofan engines for subsonic flight and variable cycle engines for supersonic flight. Ceramic- and metal-matrix composites are envisioned as the key to achievement of turbine inlet temperatures 300 C higher than the 1400 C which is characteristic of the state-of-the-art, with the requisite high stiffness, strength, and low density. Such fiber-reinforced materials can be readily tailored to furnish greatest strength in a specific direction of loading. Large, low-density engines are critical elements of future 1000-seat aircraft.

Research on aircraft emissions. Need for future work

Energy Technology Data Exchange (ETDEWEB)

Schmitt, A [German Aerospace Establishment, Cologne (Germany). Transport Research Div.

1998-12-31

Reflecting the present status of the research on aircraft emissions and their impacts upon the atmosphere, task-fields for a work programme for the research on aircraft emissions can be derived. Most important measures are to support the efforts to define adequate reduction measures, and (with highest priority) scenario-writing for the long-term development in aircraft emissions, to be able to include into the decision making process the aspect of in-time-reaction against unwanted future. Besides that, a steady monitoring of global aircraft emissions will be necessary. (author) 5 refs.

Disruption Management for an Airline - Rescheduling of aircraft

DEFF Research Database (Denmark)

Larsen, Jesper; Løve, Michael; Sørensen, Kim Riis

2002-01-01

The Aircraft Recovery Problem (ARP) involves decisions concerning aircraft to flight assignments in situations where unforseen events have disrupted the existing flight schedule, e.g. bad weather causing flight delays. The aircraft recovery problem aims to recover these flight schedules through...... a series of reassignments of aircraft to flights, delaying of flights and cancellations of flights. This article demonstrates an effective method to solve ARP. A heuristic is implemented, which is able to generate feasible revised flight schedules of a good quality in less than 10 seconds. This article...

Research on aircraft emissions. Need for future work

Energy Technology Data Exchange (ETDEWEB)

Schmitt, A. [German Aerospace Establishment, Cologne (Germany). Transport Research Div.

1997-12-31

Reflecting the present status of the research on aircraft emissions and their impacts upon the atmosphere, task-fields for a work programme for the research on aircraft emissions can be derived. Most important measures are to support the efforts to define adequate reduction measures, and (with highest priority) scenario-writing for the long-term development in aircraft emissions, to be able to include into the decision making process the aspect of in-time-reaction against unwanted future. Besides that, a steady monitoring of global aircraft emissions will be necessary. (author) 5 refs.

Commercial transport aircraft composite structures

Science.gov (United States)

Mccarty, J. E.

1983-01-01

The role that analysis plays in the development, production, and substantiation of aircraft structures is discussed. The types, elements, and applications of failure that are used and needed; the current application of analysis methods to commercial aircraft advanced composite structures, along with a projection of future needs; and some personal thoughts on analysis development goals and the elements of an approach to analysis development are discussed.

Neural networks for aircraft control

Science.gov (United States)

Linse, Dennis

1990-01-01

Current research in Artificial Neural Networks indicates that networks offer some potential advantages in adaptation and fault tolerance. This research is directed at determining the possible applicability of neural networks to aircraft control. The first application will be to aircraft trim. Neural network node characteristics, network topology and operation, neural network learning and example histories using neighboring optimal control with a neural net are discussed.

Aircraft Evaluation Using Stochastic Duels

Science.gov (United States)

2017-09-01

for Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302, and to the Office of Management and...Fighter aircraft systems and weapons designs are known to involve substantial capital investment . Due to possible budget constraints in the U.S. Navy, the...of fighter aircraft to analysts and decision-makers before they invest further resources into larger-scale, higher-resolution simulations for

Pathfinder-Plus aircraft in flight

Science.gov (United States)

1998-01-01

The Pathfinder-Plus solar-powered aircraft is shown taking off from a runway, then flying at low altitude over the ocean. The vehicle, which looks like a flying ruler, operates at low airspeed. Among the missions proposed for a solar-powered aircraft are communications relay, atmospheric studies, pipeline monitoring and gas leak detection, environmental monitoring using thermal and radar images, and disaster relief and monitoring.

NASA Johnson Space Center Aircraft Operations Division

Science.gov (United States)

Bakalyar, John A.

2018-01-01

This presentation provides a high-level overview of JSC aircraft and missions. The capabilities, including previous missions and support team, for the Super Guppy Transport (SGT) aircraft are highlighted.

Versatile Electric Propulsion Aircraft Testbed, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — An all-electric aircraft testbed is proposed to provide a dedicated development environment for the rigorous study and advancement of electrically powered aircraft....

Application of Output Predictive Algorithmic Control to a Terrain Following Aircraft System.

Science.gov (United States)

1982-03-01

non-linear regime the results from an optimal control solution may be questionable. 15 -**—• - •*- "•—"".’" CHAPTER 3 Output Prpdirl- ivf ...strongly influenced by two other factors as well - the sample time T and the least-squares cost function Q. unlike the deadbeat control law of Ref...design of aircraft control systems since these methods offer tremendous insight into the dynamic behavior of the system at relatively low cost . However

Investigating accidents involving aircraft manufactured from polymer composite materials

OpenAIRE

Dunn, Leigh

2013-01-01

This thesis looks into the examination of polymer composite wreckage from the perspective of the aircraft accident investigator. It develops an understanding of the process of wreckage examination as well as identifying the potential for visual and macroscopic interpretation of polymer composite aircraft wreckage. The in-field examination of aircraft wreckage, and subsequent interpretations of material failures, can be a significant part of an aircraft accident investigation. ...

Frequency Analysis of Aircraft hazards for License Application

International Nuclear Information System (INIS)

K. Ashley

2006-01-01

The preclosure safety analysis for the monitored geologic repository at Yucca Mountain must consider the hazard that aircraft may pose to surface structures. Relevant surface structures are located beneath the restricted airspace of the Nevada Test Site (NTS) on the eastern slope of Yucca Mountain, near the North Portal of the Exploratory Studies Facility Tunnel (Figure 1). The North Portal is located several miles from the Nevada Test and Training Range (NTTR), which is used extensively by the U.S. Air Force (USAF) for training and test flights (Figure 1). The NTS airspace, which is controlled by the U.S. Department of Energy (DOE) for NTS activities, is not part of the NTTR. Agreements with the DOE allow USAF aircraft specific use of the airspace above the NTS (Reference 2.1.1 [DIRS 103472], Section 3.1.1 and Appendix A, Section 2.1; and Reference 2.1.2 [DIRS 157987], Sections 1.26 through 1.29). Commercial, military, and general aviation aircraft fly within several miles to the southwest of the repository site in the Beatty Corridor, which is a broad air corridor that runs approximately parallel to U.S. Highway 95 and the Nevada-California border (Figure 2). These aircraft and other aircraft operations are identified and described in ''Identification of Aircraft Hazards'' (Reference 2.1.3, Sections 6 and 8). The purpose of this analysis is to estimate crash frequencies for aircraft hazards identified for detailed analysis in ''Identification of Aircraft Hazards'' (Reference 2.1.3, Section 8). Reference 2.1.3, Section 8, also identifies a potential hazard associated with electronic jamming, which will be addressed in this analysis. This analysis will address only the repository and not the transportation routes to the site. The analysis is intended to provide the basis for: (1) Categorizing event sequences related to aircraft hazards; (2) Identifying design or operational requirements related to aircraft hazards

Frequency Analysis of Aircraft hazards for License Application

Energy Technology Data Exchange (ETDEWEB)

K. Ashley

2006-10-24

The preclosure safety analysis for the monitored geologic repository at Yucca Mountain must consider the hazard that aircraft may pose to surface structures. Relevant surface structures are located beneath the restricted airspace of the Nevada Test Site (NTS) on the eastern slope of Yucca Mountain, near the North Portal of the Exploratory Studies Facility Tunnel (Figure 1). The North Portal is located several miles from the Nevada Test and Training Range (NTTR), which is used extensively by the U.S. Air Force (USAF) for training and test flights (Figure 1). The NTS airspace, which is controlled by the U.S. Department of Energy (DOE) for NTS activities, is not part of the NTTR. Agreements with the DOE allow USAF aircraft specific use of the airspace above the NTS (Reference 2.1.1 [DIRS 103472], Section 3.1.1 and Appendix A, Section 2.1; and Reference 2.1.2 [DIRS 157987], Sections 1.26 through 1.29). Commercial, military, and general aviation aircraft fly within several miles to the southwest of the repository site in the Beatty Corridor, which is a broad air corridor that runs approximately parallel to U.S. Highway 95 and the Nevada-California border (Figure 2). These aircraft and other aircraft operations are identified and described in ''Identification of Aircraft Hazards'' (Reference 2.1.3, Sections 6 and 8). The purpose of this analysis is to estimate crash frequencies for aircraft hazards identified for detailed analysis in ''Identification of Aircraft Hazards'' (Reference 2.1.3, Section 8). Reference 2.1.3, Section 8, also identifies a potential hazard associated with electronic jamming, which will be addressed in this analysis. This analysis will address only the repository and not the transportation routes to the site. The analysis is intended to provide the basis for: (1) Categorizing event sequences related to aircraft hazards; (2) Identifying design or operational requirements related to aircraft hazards.

Aircraft crash upon outer containment of nuclear power plant

International Nuclear Information System (INIS)

Abbas, H.; Paul, D.K.; Godbole, P.N.; Nayak, G.C.

1996-01-01

In this paper, analysis of an aircraft crash upon an outer containment of a nuclear power plant is presented. The effect of target yielding is considered simultaneously by calculating the reaction time in a time marching scheme. The concrete model employed is capable of predicting the cracking and yielding. The response for different cracking strains and different locations of aircraft strike for different aircraft has been studied. Critical location of aircraft strike for the containment has been investigated. The analytical procedure and the material model used are found to be capable of representing the aircraft impact response of the containment structure. (orig.)

Turboelectric Aircraft Drive Key Performance Parameters and Functional Requirements

Science.gov (United States)

Jansen, Ralph H.; Brown, Gerald V.; Felder, James L.; Duffy, Kirsten P.

2016-01-01

The purpose of this paper is to propose specific power and efficiency as the key performance parameters for a turboelectric aircraft power system and investigate their impact on the overall aircraft. Key functional requirements are identified that impact the power system design. Breguet range equations for a base aircraft and a turboelectric aircraft are found. The benefits and costs that may result from the turboelectric system are enumerated. A break-even analysis is conducted to find the minimum allowable electric drive specific power and efficiency that can preserve the range, initial weight, operating empty weight, and payload weight of the base aircraft.

Safety of Cargo Aircraft Handling Procedure

Directory of Open Access Journals (Sweden)

Daniel Hlavatý

2017-07-01

Full Text Available The aim of this paper is to get acquainted with the ways how to improve the safety management system during cargo aircraft handling. The first chapter is dedicated to general information about air cargo transportation. This includes the history or types of cargo aircraft handling, but also the means of handling. The second part is focused on detailed description of cargo aircraft handling, including a description of activities that are performed before and after handling. The following part of this paper covers a theoretical interpretation of safety, safety indicators and legislative provisions related to the safety of cargo aircraft handling. The fourth part of this paper analyzes the fault trees of events which might occur during handling. The factors found by this analysis are compared with safety reports of FedEx. Based on the comparison, there is a proposal on how to improve the safety management in this transportation company.

Delamination and debonding failure of laminated composite T-joints

NARCIS (Netherlands)

Cui, H.

2014-01-01

Composites are increasingly being used in aerospace, automotive and other industries. The T-joint (also named stringer stiffened skin) is a typical connection, broadly used in thin-walled structures, such as the wing and fuselage of aircraft. This thesis presents the analysis of the delamination and

Design definition study of a lift/cruise fan technology V/STOL aircraft. Volume 2: Technology aircraft

Science.gov (United States)

1975-01-01

Technology flight vehicles were defined for three different approaches which demonstrate the concept and characteristics of the multipurpose aircraft established for Navy missions. The propulsion system used for the various technology flight vehicles was representative of that established for the multipurpose aircraft. Existing J97-GE100 gas generators were selected based on cost, availability and exhaust characteristics. The LF459 fans were also selected and are compatible with both technology and operational vehicles. To comply with the design guideline safety criteria, it was determined that three gas generators were required to provide engine out safety in the hover flight mode. The final propulsion system established for the technology aircraft was three existing J97 gas generators powering three LF459 fans. Different aircraft candidates were evaluated for application to the three designated design approaches. Each configuration was evaluated on the basis of (1) propulsion system integration, (2) modification required, (3) pilot's visibility, (4) payload volume, and (5) adaptability to compatible location of center-of-gravity/aerodynamic center and thrust center.

14 CFR 121.538 - Aircraft security.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Aircraft security. 121.538 Section 121.538..., FLAG, AND SUPPLEMENTAL OPERATIONS Flight Operations § 121.538 Aircraft security. Certificate holders conducting operations under this part must comply with the applicable security requirements in 49 CFR chapter...

14 CFR 135.125 - Aircraft security.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Aircraft security. 135.125 Section 135.125....125 Aircraft security. Certificate holders conducting operators conducting operations under this part must comply with the applicable security requirements in 49 CFR chapter XII. [67 FR 8350, Feb. 22, 2002] ...

Advanced technology composite aircraft structures

Science.gov (United States)

Ilcewicz, Larry B.; Walker, Thomas H.

1991-01-01

Work performed during the 25th month on NAS1-18889, Advanced Technology Composite Aircraft Structures, is summarized. The main objective of this program is to develop an integrated technology and demonstrate a confidence level that permits the cost- and weight-effective use of advanced composite materials in primary structures of future aircraft with the emphasis on pressurized fuselages. The period from 1-31 May 1991 is covered.

Small Aircraft Transportation System Higher Volume Operations Concept

Science.gov (United States)

Abbott, Terence S.; Consiglio, Maria C.; Baxley, Brian T.; Williams, Daniel M.; Jones, Kenneth M.; Adams, Catherine A.

2006-01-01

This document defines the Small Aircraft Transportation System (SATS) Higher Volume Operations concept. The general philosophy underlying this concept is the establishment of a newly defined area of flight operations called a Self-Controlled Area (SCA). Within the SCA, pilots would take responsibility for separation assurance between their aircraft and other similarly equipped aircraft. This document also provides details for a number of off-nominal and emergency procedures which address situations that could be expected to occur in a future SCA. The details for this operational concept along with a description of candidate aircraft systems to support this concept are provided.

Energy Conversion and Storage Requirements for Hybrid Electric Aircraft

Science.gov (United States)

Misra, Ajay

2016-01-01

Among various options for reducing greenhouse gases in future large commercial aircraft, hybrid electric option holds significant promise. In the hybrid electric aircraft concept, gas turbine engine is used in combination with an energy storage system to drive the fan that propels the aircraft, with gas turbine engine being used for certain segments of the flight cycle and energy storage system being used for other segments. The paper will provide an overview of various energy conversion and storage options for hybrid electric aircraft. Such options may include fuel cells, batteries, super capacitors, multifunctional structures with energy storage capability, thermoelectric, thermionic or a combination of any of these options. The energy conversion and storage requirements for hybrid electric aircraft will be presented. The role of materials in energy conversion and storage systems for hybrid electric aircraft will be discussed.

77 FR 41889 - Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters

Science.gov (United States)

2012-07-17

... Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters AGENCY: Federal Aviation Administration (FAA... airworthiness directive (AD) for Sikorsky Aircraft Corporation (Sikorsky) Model S-92A helicopters. This AD... identified in this AD, contact Sikorsky Aircraft Corporation, Attn: Manager, Commercial Technical Support...

77 FR 49710 - Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters

Science.gov (United States)

2012-08-17

... Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters AGENCY: Federal Aviation Administration (FAA... Aircraft Corporation (Sikorsky) Model S-76A helicopters to require modifying the electric rotor brake (ERB... service information identified in this AD, contact Sikorsky Aircraft Corporation, Attn: Manager...

Thermal comfort assessment in civil aircraft cabins

OpenAIRE

Pang Liping; Qin Yue; Liu Dong; Liu Meng

2014-01-01

Aircraft passengers are more and demanding in terms of thermal comfort. But it is not yet easy for aircraft crew to control the environment control system (ECS) that satisfies the thermal comfort for most passengers due to a number of causes. This paper adopts a corrected predicted mean vote (PMV) model and an adaptive model to assess the thermal comfort conditions for 31 investigated flights and draws the conclusion that there does exist an uncomfortable thermal phenomenon in civil aircraft ...

Aircraft Depainting Technology

National Research Council Canada - National Science Library

Kozol, Joseph

1999-01-01

... of aircraft and component stripping at various levels of maintenance. Under this program, the Navy pursued development of non-HAP chemical paint strippers as alternatives for methylene chloride based strippers...

New entrants and overcapacity: lessons from regional aircraft manufacturing

NARCIS (Netherlands)

Steenhuis, H.J.; de Bruijn, E.J.; Heerkens, Johannes M.G.

2010-01-01

The commercial aircraft manufacturing industry has been largely dominated by the advanced economies in North America and Western Europe. During recent decades, several emerging economies have invested heavily in the commercial aircraft industry, notably in regional aircraft manufacturing. This paper

78 FR 60656 - Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters

Science.gov (United States)

2013-10-02

... Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters AGENCY: Federal Aviation Administration (FAA... Aircraft Corporation (Sikorsky) Model S-92A helicopters to require modifying the No. 1 engine forward... Sikorsky Aircraft Corporation, Attn: Manager, Commercial Technical Support, mailstop s581a, 6900 Main...

77 FR 23382 - Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters

Science.gov (United States)

2012-04-19

... Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters AGENCY: Federal Aviation Administration (FAA... Aircraft Corporation (Sikorsky) Model S-92A helicopters. This AD was prompted by the manufacturer's..., contact Sikorsky Aircraft Corporation, Attn: Manager, Commercial Technical Support, Mailstop s581a, 6900...

77 FR 21402 - Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters

Science.gov (United States)

2012-04-10

... Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters AGENCY: Federal Aviation Administration (FAA... Aircraft Corporation (Sikorsky) Model S-92A helicopters. This AD was prompted by the discovery of tail... identified in this AD, contact Sikorsky Aircraft Corporation, Attn: Manager, Commercial Technical Support...

A Generic Approach to Analyze the Impact of a Future Aircraft Design on the Boarding Process

Directory of Open Access Journals (Sweden)

Bekir Yildiz

2018-01-01

Full Text Available The turnaround process constitutes an important part of the air transportation system. Airports often represent bottlenecks in air traffic management (ATM, thus operations related to the preparation of the aircraft for the next flight leg have to be executed smoothly and in a timely manner. The ATM significantly depends on a reliable turnaround process. Future paradigm changes with respect to airplane energy sources, aircraft design or propulsion concepts will also influence the airport layout. As a consequence, operational processes associated with the turnaround will be affected. Airlines aim for efficient and timely turnaround operations that are correlated with higher profits. This case study discusses an approach to investigate a new aircraft design with respect to the implications on the turnaround. The boarding process, as part of the turnaround, serves as an example to evaluate the consequences of new design concepts. This study is part of an interdisciplinary research to investigate future energy, propulsion and designs concepts and their implications on the whole ATM system. Due to these new concepts, several processes of the turnaround will be affected. For example, new energy storage concepts will influence the fueling process on the aircraft itself or might lead to a new infrastructure at the airport. This paper aims to evaluate the applied methodology in the case of a new boarding process, due to a new aircraft design, by means of a generic example. An agent-based boarding simulation is applied to assess passenger behavior during boarding, particularly with regard to cabin layout and seat configuration. The results of the generic boarding simulation are integrated into a simplified, deterministic and generic simulation of the turnaround process. This was done to assess the proposed framework for future investigations which on the one hand address the ATM system holistically and on the other, incorporate additional or adapted

Towards safe and effective CD38-CAR T cell therapy for myeloma

NARCIS (Netherlands)

Drent, Esther

2018-01-01

Immunotherapy is a promising field within cancer therapy. The recent progresses resulted in 'Immunotherapy for the treatment of cancer' as break-through of the year in 2013. This was partly due to the great successes with Chimeric Antigen Receptor (CAR) T cell therapy. With CAR T cells, recognition

Beryllium in aircraft brakes - a summary

International Nuclear Information System (INIS)

Zenczak, S.

1977-01-01

Beryllium has been in use in aircraft brakes for ten years. During the original design phases of the several aircraft programs using beryllium a number of problems requiring solution confronted the designers. In actual service the solution to these problems performed much better than had been anticipated. A summary is presented. (author)

Back pain and its consequences among Polish Air Force pilots flying high performance aircraft

Directory of Open Access Journals (Sweden)

Aleksandra Truszczyńska

2014-04-01

Full Text Available Objectives: Back pain in Air Force fast jet pilots has been studied by several air forces and found to be relatively common. The objective of the study was to determine the prevalence and degree of the pain intensity in the cervical, thoracic and lumbar spine, subjective risk factors and their effect on the pilots' performance while flying high maneuver aircrafts and the consequences for cognitive deficiencies. Material and Methods: The study was designed as a retrospective, anonymous questionnaire survey, collecting data on the age, aircraft type, flying hours, pain characteristics, physical activity, etc. The study was participated by 94 pilots aged 28-45 years (mean age: 35.9±3.3 years, actively flying fast jet aircrafts Su-22, Mig-29 and F-16. The estimates regarding the level of the subjective back pain were established using visual analogue scales (VAS. Results: The values of the Cochran and Cox T-test for heterogeneous variances are as follows: for the total number of flying hours: F = 2.53, p = 0.0145, for the pilot's age: F = 3.15, p = 0.003, and for the BMI factor F = 2.73, p = 0.008. Conclusions: Our questionnaire survey showed a significant problem regarding spinal conditions in high performance aircraft pilots. The determination of the risk factors may lead to solving this problem and help eliminate the effect of the unfavorable environment on piloting jet aircrafts. Experiencing back pain during the flight might influence the mission performance and flight safety. The costs of pilots education are enormous and inability to fly, or even disability, leads to considerable economic loss. More research on specific prevention strategies is warranted in order to improve the in-flight working environment of fighter pilots.

Modeling Aircraft Emissions for Regional-scale Air Quality: Adapting a New Global Aircraft Emissions Database for the U.S

Science.gov (United States)

Arunachalam, S.; Baek, B. H.; Vennam, P. L.; Woody, M. C.; Omary, M.; Binkowski, F.; Fleming, G.

2012-12-01

Commercial aircraft emit substantial amounts of pollutants during their complete activity cycle that ranges from landing-and-takeoff (LTO) at airports to cruising in upper elevations of the atmosphere, and affect both air quality and climate. Since these emissions are not uniformly emitted over the earth, and have substantial temporal and spatial variability, it is vital to accurately evaluate and quantify the relative impacts of aviation emissions on ambient air quality. Regional-scale air quality modeling applications do not routinely include these aircraft emissions from all cycles. Federal Aviation Administration (FAA) has developed the Aviation Environmental Design Tool (AEDT), a software system that dynamically models aircraft performance in space and time to calculate fuel burn and emissions from gate-to-gate for all commercial aviation activity from all airports globally. To process in-flight aircraft emissions and to provide a realistic representation of these for treatment in grid-based air quality models, we have developed an interface processor called AEDTproc that accurately distributes full-flight chorded emissions in time and space to create gridded, hourly model-ready emissions input data. Unlike the traditional emissions modeling approach of treating aviation emissions as ground-level sources or processing emissions only from the LTO cycles in regional-scale air quality studies, AEDTproc distributes chorded inventories of aircraft emissions during LTO cycles and cruise activities into a time-variant 3-D gridded structure. We will present results of processed 2006 global emissions from AEDT over a continental U.S. modeling domain to support a national-scale air quality assessment of the incremental impacts of aircraft emissions on surface air quality. This includes about 13.6 million flights within the U.S. out of 31.2 million flights globally. We will focus on assessing spatio-temporal variability of these commercial aircraft emissions, and

Civil aircraft side-facing seat research summary.

Science.gov (United States)

2012-11-01

The Federal Aviation Administration (FAA) has standards and regulations that are intended to protect aircraft : occupants in the event of a crash. However, side-facing seats were not specifically addressed when aircraft seat : dynamic test standards ...

Aircraft Icing Weather Data Reporting and Dissemination System

Science.gov (United States)

Bass, Ellen J.; Minsk, Brian; Lindholm, Tenny; Politovich, Marcia; Reehorst, Andrew (Technical Monitor)

2002-01-01

The long-term operational concept of this research is to develop an onboard aircraft system that assesses and reports atmospheric icing conditions automatically and in a timely manner in order to improve aviation safety and the efficiency of aircraft operations via improved real-time and forecast weather products. The idea is to use current measurement capabilities on aircraft equipped with icing sensors and in-flight data communication technologies as a reporting source. Without requiring expensive avionics upgrades, aircraft data must be processed and available for downlink. Ideally, the data from multiple aircraft can then be integrated (along with other real-time and modeled data) on the ground such that aviation-centered icing hazard metrics for volumes of airspace can be assessed. As the effect of icing on different aircraft types can vary, the information should be displayed in meaningful ways such that multiple types of users can understand the information. That is, information must be presented in a manner to allow users to understand the icing conditions with respect to individual concerns and aircraft capabilities. This research provides progress toward this operational concept by: identifying an aircraft platform capable of digitally capturing, processing, and downlinking icing data; identifying the required in situ icing data processing; investigating the requirements for routing the icing data for use by weather products; developing an icing case study in order to gain insight into major air carrier needs; developing and prototyping icing display concepts based on the National Center for Atmospheric Research's existing diagnostic and forecast experimental icing products; and conducting a usability study for the prototyped icing display concepts.

A fuselage/tank structure study for actively cooled hypersonic cruise vehicles, summary. [aircraft design of aircraft fuel systems

Science.gov (United States)

Pirrello, C. J.; Baker, A. H.; Stone, J. E.

1976-01-01

A detailed analytical study was made to investigate the effects of fuselage cross section (circular and elliptical) and the structural arrangement (integral and nonintegral tanks) on aircraft performance. The vehicle was a 200 passenger, liquid hydrogen fueled Mach 6 transport designed to meet a range goal of 9.26 Mn (5000 NM). A variety of trade studies were conducted in the area of configuration arrangement, structural design, and active cooling design in order to maximize the performance of each of three point design aircraft: (1) circular wing-body with nonintegral tanks, (2) circular wing-body with integral tanks and (3) elliptical blended wing-body with integral tanks. Aircraft range and weight were used as the basis for comparison. The resulting design and performance characteristics show that the blended body integral tank aircraft weights the least and has the greatest range capability, however, producibility and maintainability factors favor nonintegral tank concepts.

Hull loss accident model for narrow body commercial aircraft

Directory of Open Access Journals (Sweden)

Somchanok Tiabtiamrat

2010-10-01

Full Text Available Accidents with narrow body aircraft were statistically evaluated covering six families of commercial aircraft includingBoeing B737, Airbus A320, McDonnell Douglas MD80, Tupolev TU134/TU154 and Antonov AN124. A risk indicator for eachflight phase was developed based on motion characteristics, duration time, and the presence of adverse weather conditions.The estimated risk levels based on these risk indicators then developed from the risk indicator. Regression analysis indicatedvery good agreement between the estimated risk level and the accident ratio of hull loss cases per number of delivered aircraft.The effect of time on the hull loss accident ratio per delivered aircraft was assessed for B737, A320 and MD80. Equationsrepresenting the effect of time on hull loss accident ratio per delivered aircraft were proposed for B737, A320, and MD80,while average values of hull loss accident ratio per delivered aircraft were found for TU134, TU154, and AN 124. Accidentprobability equations were then developed for each family of aircraft that the probability of an aircraft in a hull loss accidentcould be estimated for any aircraft family, flight phase, presence of adverse weather factor, hour of day, day of week, monthof year, pilot age, and pilot flight hour experience. A simplified relationship between estimated hull loss accident probabilityand unsafe acts by human was proposed. Numerical investigation of the relationship between unsafe acts by human andfatality ratio suggested that the fatality ratio in hull loss accident was dominated primarily by the flight phase media.

Application of automation for low cost aircraft cabin simulator

NARCIS (Netherlands)

Tan, C.F.; Chen, W.; Boomen, van den G.J.A.; Rauterberg, G.W.M.

2010-01-01

This paper presents an application of automation for low cost aircraft cabin simulator. The aircraft cabin simulator is a testbed that was designed for research on aircraft passenger comfort mprovement product. The simulator consists of an economy class section, a business class section, a lavatory

Fleet Management Decision Making With Individual Aircraft Tracking Data

NARCIS (Netherlands)

Newcamp, Jeffrey; Verhagen, W.J.C.; Curran, R.

2017-01-01

Individual aircraft tracking data can be used by aircraft fleet managers to detect patterns in historical usage as a means to aid aging aircraft decision-making. This work tackles two aspects of applying these tracking data: investigating retirement patterns and assessing how base assignment can

77 FR 68058 - Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters

Science.gov (United States)

2012-11-15

... Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters AGENCY: Federal Aviation Administration (FAA... airworthiness directive (AD) for Sikorsky Aircraft Corporation (Sikorsky) Model S-70, S-70A, S-70C, S-70C(M... after receipt. For service information identified in this AD, contact Sikorsky Aircraft Corporation...

Aircraft Landing and Attitude Control Using Dynamic Matrix Control

Directory of Open Access Journals (Sweden)

George Cristian Calugaru

2017-06-01

Full Text Available This paper proposes a method for an efficient control of the aircraft landing and attitude through Dynamic Matrix Control. The idea of MPC structures used in aircraft control has been well established during the last few years, but some aspects require further investigation. With this in mind, the paper proposes structures for aircraft landing and aircraft attitude control by using single DMC controllers for landing and respectively one DMC controller for each of the attitude axis (pitch attitude hold, bank angle hold and heading hold. The model used for analysis of the aircraft landing structure is based on the last phase of landing. Also, the model used to illustrate the attitude control is that of a pitch attitude hold system of a N250-100 aircraft. Simulations are performed for a variety of control and prediction horizons, taking into account the possibility of adding a weighting factor for the control actions. Apart from separate studies on step reference variations, for some use cases, a generic reference trajectory is provided as a control purpose of the system. Results show a better performance of the proposed method in terms of control surface transition and protection of the actuators involved and a better time response in stabilizing the aircraft attitude. Overall, the aspects shown ensure an improved aircraft attitude control and landing stabilization.

Atmospheric/climatic effects of aircraft emissions

International Nuclear Information System (INIS)

Pueschel, R.F.

1996-01-01

Exhaust emissions from aircraft include oxides of nitrogen (NO x ), water vapor (H 2 O), sulfur dioxide (SO 2 ), carbon dioxide (CO 2 ), carbon monoxide (CO), hydrocarbons (HC) and particles (soot and sulfates). These emissions are small compared to industrial/urban surface emissions. However, because (1) atmospheric residence times of exhaust constituents are longer at altitude, particularly in the stratosphere, than they are in the boundary layer, (2) their background concentrations at altitude are lower than those near the surface, (3) the radiation balance is the more sensitive to atmospheric trace constituents the colder the temperature aloft and (4) inter-hemispheric mixing of aircraft effluents is inhibited, aircraft emissions near and above the tropopause and polewards of 40 degrees latitude can be environmentally critical. That's why atmospheric/climatic effects of aircraft emissions have again received scientific, economic and political scrutiny in the last few years, motivated by growth of subsonic traffic at about 5% per year over the past two decades and the advent of a technologically feasible operation of a supersonic high speed commercial transport (HSCT) fleet

Aircraft Fuel Cell Power Systems

Science.gov (United States)

Needham, Robert

2004-01-01

In recent years, fuel cells have been explored for use in aircraft. While the weight and size of fuel cells allows only the smallest of aircraft to use fuel cells for their primary engines, fuel cells have showed promise for use as auxiliary power units (APUs), which power aircraft accessories and serve as an electrical backup in case of an engine failure. Fuel cell MUS are both more efficient and emit fewer pollutants. However, sea-level fuel cells need modifications to be properly used in aircraft applications. At high altitudes, the ambient air has a much lower pressure than at sea level, which makes it much more difficult to get air into the fuel cell to react and produce electricity. Compressors can be used to pressurize the air, but this leads to added weight, volume, and power usage, all of which are undesirable things. Another problem is that fuel cells require hydrogen to create electricity, and ever since the Hindenburg burst into flames, aircraft carrying large quantities of hydrogen have not been in high demand. However, jet fuel is a hydrocarbon, so it is possible to reform it into hydrogen. Since jet fuel is already used to power conventional APUs, it is very convenient to use this to generate the hydrogen for fuel-cell-based APUs. Fuel cells also tend to get large and heavy when used for applications that require a large amount of power. Reducing the size and weight becomes especially beneficial when it comes to fuel cells for aircraft. My goal this summer is to work on several aspects of Aircraft Fuel Cell Power System project. My first goal is to perform checks on a newly built injector rig designed to test different catalysts to determine the best setup for reforming Jet-A fuel into hydrogen. These checks include testing various thermocouples, transmitters, and transducers, as well making sure that the rig was actually built to the design specifications. These checks will help to ensure that the rig will operate properly and give correct results

PREPARATION OF BLOCK COPOLYMERS OF POLY(STYRENE) AND POLY(T-BUTYL ACRYLATE) OF VARIOUS MOLECULAR WEIGHTS AND ARCHITECTURES BY ATOM TRANSFER RADICAL POLYMERIZATION. (R826735)

Science.gov (United States)

Block copolymers of polystyrene and poly(t-butyl acrylate) were prepared using atom transfer radical polymerization techniques. These polymers were synthesized with a CuBr/N,N,N,NAnalysis of Aircraft Crash Accident for WETF

International Nuclear Information System (INIS)

Jordan, Hans

2001-01-01

This report applies the methodology of DOE-STD-3014-96, ''Accident Analysis for Aircraft Crash into Hazardous Facilities'', to the Weapons Engineering Tritium Facility (WETF) at LANL. Straightforward application of that methodology shows that including local helicopter flights with those of all other aircraft with potential to impact the facility poses a facility impact risk slightly in excess of the DOE standard's threshold--10 -6 impacts per year. It is also shown that helicopters can penetrate the facility if their engines impact that facility's roof. However, a refinement of the helicopter impact analysis shows that penetration risk of the facility for all aircraft lies below the DOE standard's threshold. By that standard, therefore, the potential for release of hazardous material from the facility as a result of an aircraft crashing into the facility is negligible and need not be analyzed further

Emerging nondestructive inspection methods for aging aircraft

Energy Technology Data Exchange (ETDEWEB)

Beattie, A; Dahlke, L; Gieske, J [and others

1994-01-01

This report identifies and describes emerging nondestructive inspection (NDI) methods that can potentially be used to inspect commercial transport and commuter aircraft for structural damage. The nine categories of emerging NDI techniques are: acoustic emission, x-ray computed tomography, backscatter radiation, reverse geometry x-ray, advanced electromagnetics, including magnetooptic imaging and advanced eddy current techniques, coherent optics, advanced ultrasonics, advanced visual, and infrared thermography. The physical principles, generalized performance characteristics, and typical applications associated with each method are described. In addition, aircraft inspection applications are discussed along with the associated technical considerations. Finally, the status of each technique is presented, with a discussion on when it may be available for use in actual aircraft maintenance programs. It should be noted that this is a companion document to DOT/FAA/CT-91/5, Current Nondestructive Inspection Methods for Aging Aircraft.

In Preparation of the Nationwide Dissemination of the School-Based Obesity Prevention Program DOiT: Stepwise Development Applying the Intervention Mapping Protocol

Science.gov (United States)

van Nassau, Femke; Singh, Amika S.; van Mechelen, Willem; Brug, Johannes; Chin A. Paw, Mai J. M.

2014-01-01

Background: The school-based Dutch Obesity Intervention in Teenagers (DOiT) program is an evidence-based obesity prevention program. In preparation for dissemination throughout the Netherlands, this study aimed to adapt the initial program and to develop an implementation strategy and materials. Methods: We revisited the Intervention Mapping (IM)…

Government financial support for civil aircraft research, technology and development in four European countries and the United States

Science.gov (United States)

Chandler, B.; Golaszewski, R.; Patten, C.; Rudman, B.; Scott, R.

1980-01-01

Data on the levels of government financial support for civil aircraft airframe and engine (CAAE) research and technology (R&T) in the United States and Europe (United Kingdom, West Germany, France and The Netherlands) and means of comparing these levels are provided. Data are presented for the years 1974-1977. European R&T expenditure data were obtained through visits to each of the four European countries, to the Washington office of the European Communities, and by a search of applicable literature. CAAE R&T expenditure data for the United States were obtained from NASA and Federal Aviation Administration (FAA).

Unmanned aircraft system bridge inspection demonstration project phase II final report.

Science.gov (United States)

2017-06-01

An Unmanned Aircraft System (UAS) is defined by the Federal Aviation Administration (FAA) as an aircraft operated without the possibility of direct human intervention from within the aircraft. Unmanned aircraft are familiarly referred to as drones, a...

78 FR 9796 - Airworthiness Directives; Cessna Aircraft Company Airplanes

Science.gov (United States)

2013-02-12

... (2) Model 172S, S/N l72S11074 through 172S11193. (d) Subject Joint Aircraft System Component (JASC)/Air Transport Association (ATA) of America Code 2820, Aircraft Fuel Distribution System. (e) Unsafe... Airworthiness Directives; Cessna Aircraft Company Airplanes AGENCY: Federal Aviation Administration (FAA), DOT...

77 FR 72250 - Airworthiness Directives; Cessna Aircraft Company Airplanes

Science.gov (United States)

2012-12-05

... Joint Aircraft System Component (JASC)/Air Transport Association (ATA) of America Code 2820, Aircraft Fuel Distribution System. (e) Unsafe Condition This AD was prompted by reports of chafing of a new... flight, reinstall the fuel return line assembly (Cessna P/N 0516031-1) following Cessna Aircraft Company...

77 FR 50054 - Airworthiness Directives; Cessna Aircraft Company Airplanes

Science.gov (United States)

2012-08-20

... Aircraft Company Service Bulletin SB04-28-03, dated August 30, 2004, and Engine Fuel Return System... Transport Association (ATA) of America Code 2820, Aircraft Fuel Distribution System. (e) Unsafe Condition... Fuel Return System Modification Do not install Cessna Aircraft Company Service Bulletin SB 04- 28-03...

78 FR 26556 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

Science.gov (United States)

2013-05-07

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 [Docket No. FAA-2012-0756; Directorate Identifier 2012-CE-012-AD] RIN 2120-AA64 Airworthiness Directives; Piper Aircraft... Piper Aircraft, Inc. (type certificate previously held by The New Piper Aircraft Inc.) Models PA-18 and...

77 FR 67561 - Airworthiness Directives; Univair Aircraft Corporation Airplanes

Science.gov (United States)

2012-11-13

... Airworthiness Directives; Univair Aircraft Corporation Airplanes AGENCY: Federal Aviation Administration (FAA...) that published in the Federal Register. That AD applies to certain Univair Aircraft Corporation Models... throughout the AD for Univair Aircraft Corporation Models (ERCO) 415-C, 415-CD, 415-D, E, G; (Forney) F-1 and...

Operation of a T63 Turbine Engine Using F24 Contaminated Skydrol 5 Hydraulic Fluid

Science.gov (United States)

2016-09-01

hydraulic fluids were originally developed by the Douglas Aircraft Company during the 1940s to reduce fire risk from leaking high pressure mineral oil...thermal load demands in modern hydraulic systems and reduced density to lower weight impact on the aircraft. Eastman Chemical is the current producer of...AFRL-RQ-WP-TM-2016-0155 OPERATION OF A T63 TURBINE ENGINE USING F24 CONTAMINATED SKYDROL 5 HYDRAULIC FLUID Matthew J. Wagner (AFRL/RQTM) James

Aircraft Design Software

Science.gov (United States)

1997-01-01

Successful commercialization of the AirCraft SYNThesis (ACSYNT) tool has resulted in the creation of Phoenix Integration, Inc. ACSYNT has been exclusively licensed to the company, an outcome of a seven year, $3 million effort to provide unique software technology to a focused design engineering market. Ames Research Center formulated ACSYNT and in working with the Virginia Polytechnic Institute CAD Laboratory, began to design and code a computer-aided design for ACSYNT. Using a Joint Sponsored Research Agreement, Ames formed an industry-government-university alliance to improve and foster research and development for the software. As a result of the ACSYNT Institute, the software is becoming a predominant tool for aircraft conceptual design. ACSYNT has been successfully applied to high- speed civil transport configuration, subsonic transports, and supersonic fighters.

Aircraft Electric/Hybrid-Electric Power and Propulsion Workshop Perspective of the V/STOL Aircraft Systems Tech Committee

Science.gov (United States)

Hange, Craig E.

2016-01-01

This presentation will be given at the AIAA Electric Hybrid-Electric Power Propulsion Workshop on July 29, 2016. The workshop is being held so the AIAA can determine how it can support the introduction of electric aircraft into the aerospace industry. This presentation will address the needs of the community within the industry that advocates the use of powered-lift as important new technologies for future aircraft and air transportation systems. As the current chairman of the VSTOL Aircraft Systems Technical Committee, I will be presenting generalized descriptions of the past research in developing powered-lift and generalized observations on how electric and hybrid-electric propulsion may provide advances in the powered-lift field.

Fuel-Conservation Guidance System for Powered-Lift Aircraft

Science.gov (United States)

Erzberger, Heinz; McLean, John D.

1981-01-01

A technique is described for the design of fuel-conservative guidance systems and is applied to a system that was flight tested on board NASA's sugmentor wing jet STOL research aircraft. An important operational feature of the system is its ability to rapidly synthesize fuel-efficient trajectories for a large set of initial aircraft positions, altitudes, and headings. This feature allows the aircraft to be flown efficiently under conditions of changing winds and air traffic control vectors. Rapid synthesis of fuel-efficient trajectories is accomplished in the airborne computer by fast-time trajectory integration using a simplified dynamic performance model of the aircraft. This technique also ensures optimum flap deployment and, for powered-lift STOL aircraft, optimum transition to low-speed flight. Also included in the design is accurate prediction of touchdown time for use in four-dimensional guidance applications. Flight test results have demonstrated that the automatically synthesized trajectories produce significant fuel savings relative to manually flown conventional approaches.

Investigation of incidents of terrorism involving commercial aircraft.

Science.gov (United States)

Clark, M A; Wagner, G N; Wright, D G; Ruehle, C J; McDonnell, E W

1989-07-01

Deaths resulting from terrorism involving aircraft have occurred incident to hijackings as well as bombings. Passengers or groups of passengers have been chosen by terrorists as the recipients of violence based on citizenship, religion, and political beliefs. They have usually been segregated from other passengers and subsequently mistreated and/or murdered. Thorough documentation of the injuries of victims is essential to the investigation of such atrocities; a medicolegal autopsy correlated with a scene investigation is of paramount importance. Aircraft bombings can create extremely sensitive political situations and public demands for quick resolution. The autopsy of victims in such circumstances, if properly conducted, can yield invaluable trace evidence leading to the identification of the explosive device. The examination of any surviving victims as well as the aircraft is also critical in reconstructing the event. Deaths occurring as the result of in-flight aircraft bombings can produce injuries by five different mechanisms, viz. blast, shrapnel, decompression, impact with the aircraft, and ground impact.

76 FR 70379 - Airworthiness Directives; Cessna Aircraft Company Airplanes

Science.gov (United States)

2011-11-14

...) Subject Joint Aircraft System Component (JASC)/Air Transport Association (ATA) of America Code Fuel, 28...-1245; Directorate Identifier 2011-CE-033-AD; RIN 2120-AA64] Airworthiness Directives; Cessna Aircraft... certain Cessna Aircraft Company (Cessna) Models 172R and 172S airplanes. The existing AD requires you to...

77 FR 42455 - Airworthiness Directives; Piper Aircraft, Inc. Airplanes

Science.gov (United States)

2012-07-19

...-0756; Directorate Identifier 2012-CE-012-AD] RIN 2120-AA64 Airworthiness Directives; Piper Aircraft... adopt a new airworthiness directive (AD) for all Piper Aircraft, Inc. (type certificate previously held by The New Piper Aircraft Inc.) Models PA-18 and PA-19 airplanes. This proposed AD was prompted by...

An aircraft noise pollution model for trajectory optimization

Science.gov (United States)

Barkana, A.; Cook, G.

1976-01-01

A mathematical model describing the generation of aircraft noise is developed with the ultimate purpose of reducing noise (noise-optimizing landing trajectories) in terminal areas. While the model is for a specific aircraft (Boeing 737), the methodology would be applicable to a wide variety of aircraft. The model is used to obtain a footprint on the ground inside of which the noise level is at or above 70 dB.

77 FR 65823 - Control of Air Pollution From Aircraft and Aircraft Engines; Emission Standards and Test Procedures

Science.gov (United States)

2012-10-31

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Parts 87 [EPA-HQ-OAR-2010-0687; FRL-9678-1] RIN 2060-AO70 Control of Air Pollution From Aircraft and Aircraft Engines; Emission Standards and Test Procedures Correction In rule document 2012-13828 appearing on pages 36341-36386 in the issue of Monday, June 18, 2012, make the following corrections: Sec. 87.2...

Aircraft Wake Vortex Measurement with Coherent Doppler Lidar

Directory of Open Access Journals (Sweden)

Wu Songhua

2016-01-01

Full Text Available Aircraft vortices are generated by the lift-producing surfaces of the aircraft. The variability of near-surface conditions can change the drop rate and cause the cell of the wake vortex to twist and contort unpredictably. The pulsed Coherent Doppler Lidar Detection and Ranging is an indispensable access to real aircraft vortices behavior which transmitting a laser beam and detecting the radiation backscattered by atmospheric aerosol particles. Experiments for Coherent Doppler Lidar measurement of aircraft wake vortices has been successfully carried out at the Beijing Capital International Airport (BCIA. In this paper, the authors discuss the Lidar system, the observation modes carried out in the measurements at BCIA and the characteristics of vortices.

A strategic planning methodology for aircraft redesign

Science.gov (United States)

Romli, Fairuz Izzuddin

Due to a progressive market shift to a customer-driven environment, the influence of engineering changes on the product's market success is becoming more prominent. This situation affects many long lead-time product industries including aircraft manufacturing. Derivative development has been the key strategy for many aircraft manufacturers to survive the competitive market and this trend is expected to continue in the future. Within this environment of design adaptation and variation, the main market advantages are often gained by the fastest aircraft manufacturers to develop and produce their range of market offerings without any costly mistakes. This realization creates an emphasis on the efficiency of the redesign process, particularly on the handling of engineering changes. However, most activities involved in the redesign process are supported either inefficiently or not at all by the current design methods and tools, primarily because they have been mostly developed to improve original product development. In view of this, the main goal of this research is to propose an aircraft redesign methodology that will act as a decision-making aid for aircraft designers in the change implementation planning of derivative developments. The proposed method, known as Strategic Planning of Engineering Changes (SPEC), combines the key elements of the product redesign planning and change management processes. Its application is aimed at reducing the redesign risks of derivative aircraft development, improving the detection of possible change effects propagation, increasing the efficiency of the change implementation planning and also reducing the costs and the time delays due to the redesign process. To address these challenges, four research areas have been identified: baseline assessment, change propagation prediction, change impact analysis and change implementation planning. Based on the established requirements for the redesign planning process, several methods and

77 FR 52205 - Airworthiness Directives; Univair Aircraft Corporation Airplanes

Science.gov (United States)

2012-08-29

... Airworthiness Directives; Univair Aircraft Corporation Airplanes AGENCY: Federal Aviation Administration (FAA... certain Univair Aircraft Corporation Models (ERCO) 415-C, 415-CD, 415-D, E, G; (Forney) F-1 and F-1A... inspection results. This new AD was prompted by a report of a Univair Aircraft Corporation Model ERCO 415-D...

Time to retire : Indicators for aircraft fleets

NARCIS (Netherlands)

Newcamp, Jeffrey; Verhagen, W.J.C.; Curran, R.

2017-01-01

It is well known that aircraft fleets are aging alongside rising operations and support costs. Logisticians and fleet managers who better understand the milestones and timeline of an aging fleet can recognise potential savings. This paper outlines generalised milestones germane to military aircraft

Application of variable structure system theory to aircraft flight control. [AV-8A and the Augmentor Wing Jet STOL Research Aircraft

Science.gov (United States)

Calise, A. J.; Kadushin, I.; Kramer, F.

1981-01-01

The current status of research on the application of variable structure system (VSS) theory to design aircraft flight control systems is summarized. Two aircraft types are currently being investigated: the Augmentor Wing Jet STOL Research Aircraft (AWJSRA), and AV-8A Harrier. The AWJSRA design considers automatic control of longitudinal dynamics during the landing phase. The main task for the AWJSRA is to design an automatic landing system that captures and tracks a localizer beam. The control task for the AV-8A is to track velocity commands in a hovering flight configuration. Much effort was devoted to developing computer programs that are needed to carry out VSS design in a multivariable frame work, and in becoming familiar with the dynamics and control problems associated with the aircraft types under investigation. Numerous VSS design schemes were explored, particularly for the AWJSRA. The approaches that appear best suited for these aircraft types are presented. Examples are given of the numerical results currently being generated.

Kauha : [luuletused] / Pjotr Zahharov ; udmurdi keelest tõlkinud soome keelde Viktor Shibanov, Hannu Oittinen, võru keelde tõlkinud Irina Orehhova, Kauksi Ülle, eesti keelde tõlkinud Taive Särg

Index Scriptorium Estoniae

Zahharov, Pjotr

2005-01-01

Sisu: Kauha / udmurdi keelest tõlkinud soome keelde Viktor Shibanov, Hannu Oittinen ; Kopsik / udmurdi keelest tõlkinud võru keelde Irina Orehhova, Kauksi Ülle ; Pu-pu : seitse pühendust rähnile 1, 3, 4, 4, 5-7 / udmurdi keelest tõlkinud eesti keelde Irina Orehhova, Taive Särg ; Metamorfoosid 3-8 / udmurdi keelest tõlkinud eesti keelde Irina Orehhova, Taive Särg

Quantitative Inspection Technologies for Aging Military Aircraft

Science.gov (United States)

2013-11-01

Bowler, J. R., Theodoulidis, T. and Polakis, N. 2012, IEEE Trans. Mag.- IEEE Xplore . 45. Xie, H., Ji, Y. and Bowler, J. R. Eddy Current Pancake Coil...March 2012, IEEE Trans. Mag, Vol. 48, pp. 1159-1170. 38. Impedance of a Horizontal Coil in a Borehole: A Model for Eddy-Current Borehole Probes...40. Waves and Fields in Inhomogeneous Media. Chew, W. C. New York: s.n., 1995, IEEE Press. 41. Thin-Skin Eddy-Current Interaction with Semi

Integrated controls pay-off. [for flight/propulsion aircraft systems

Science.gov (United States)

Putnam, Terrill W.; Christiansen, Richard S.

1989-01-01

It is shown that the integration of the propulsion and flight control systems for high performance aircraft can help reduce pilot workload while simultaneously increasing overall aircraft performance. Results of the Highly Integrated Digital Electronic Control (HiDEC) flight research program are presented to demonstrate the emerging payoffs of controls integration. Ways in which the performance of fighter aircraft can be improved through the use of propulsion for primary aircraft control are discussed. Research being conducted by NASA with the F-18 High Angle-of Attack Research Vehicle is described.

78 FR 25363 - Airworthiness Directives; Diamond Aircraft Industries Airplanes

Science.gov (United States)

2013-05-01

... holidays. For service information identified in this AD, contact Diamond Aircraft Industries GmbH, N.A... Aircraft Industries GmbH has issued Mandatory Service Bulletin 40NG-018/1, dated November 20, 2012. The... Aircraft Industries GmbH Mandatory Service Bulletin 40NG-018/1, dated November 26, 2012. (2) If chafing...

Design Of Vertical Take-Off And Landing VTOL Aircraft System

Directory of Open Access Journals (Sweden)

Win Ko Ko Oo

2017-04-01

Full Text Available Vertical Take Off and Landing Vehicles VTOL are the ones which can take off and land from the same place without need of long runway. This paper presents the design and implementation of tricopter mode and aircraft mode for VTOL aircraft system. Firstly the aircraft design is considered for VTOL mode. And then the mathematical model of the VTOL aircraft is applied to test stability. In this research the KK 2.1 flight controller is used for VTOL mode and aircraft mode. The first part is to develop the VTOL mode and the next part is the transition of VTOL mode to aircraft mode. This paper gives brief idea about numerous types of VTOLs and their advantages over traditional aircraftsand insight to various types of tricopter and evaluates their configurations.

Fast Aircraft Turnaround Enabled by Reliable Passenger Boarding

OpenAIRE

Michael Schultz

2018-01-01

Future 4D aircraft trajectories demand comprehensive consideration of environmental, economic, and operational constraints, as well as reliable prediction of all aircraft-related processes. Mutual interdependencies between airports result in system-wide, far-reaching effects in the air traffic network (reactionary delays). To comply with airline/airport challenges over the day of operations, a change to an air-to-air perspective is necessary, with a specific focus on the aircraft ground opera...

Y2K: prepare, don't panic.

Science.gov (United States)

Russo, R

1999-04-01

Y2K issues could affect anyone, so it is important for HIV-positive people to make preparations to ensure their health and security. There are wide-ranging opinions about the effects of the so-called Millennium Bug, but some planning will make any changes more manageable. Patients should have adequate supplies of food, water, and medications at home in case of shortages or production problems. Other prudent steps include keeping extra cash on hand and obtaining copies of medical records and benefit plans. Internet resources are listed.

Inductive sensor for lightning current measurement, fitted in aircraft windows, part II: Measurements on an A320 aircraft

NARCIS (Netherlands)

Deursen, van A.P.J.

2011-01-01

A novel sensor for the detection of the lightning current through the fuselage of an aircraft has been tested on an A320 aircraft. An accurate method-of-moment model of the window edge provided reliable calibration of the sensor for external fields. The data have been analyzed and the good

Aircraft bi-level life cycle cost estimation

NARCIS (Netherlands)

Zhao, X.; Verhagen, W.J.C.; Curan, R.

2015-01-01

n an integrated aircraft design and analysis practice, Life Cycle Cost (LCC) is essential for decision making. The LCC of an aircraft is ordinarily partially estimated by emphasizing a specific cost type. However, an overview of the LCC including design and development cost, production cost,

Fault Tolerance, Diagnostics, and Prognostics in Aircraft Flight

Data.gov (United States)

National Aeronautics and Space Administration — Abstract In modern fighter aircraft with statically unstable airframe designs, the flight control system is considered flight critical, i.e. the aircraft will...

Use of p38 MAPK Inhibitors for the Treatment of Werner Syndrome

Directory of Open Access Journals (Sweden)

Mark C. Bagley

2010-06-01

Full Text Available Werner syndrome provides a convincing model for aspects of the normal ageing phenotype and may provide a suitable model for therapeutic interventions designed to combat the ageing process. Cultured primary fibroblast cells from Werner syndrome patients provide a powerful model system to study the link between replicative senescence in vitro and in vivo pathophysiology. Genome instability, together with an increased pro-oxidant state, and frequent replication fork stalling, all provide plausible triggers for intracellular stress in Werner syndrome cells, and implicates p38 MAPK signaling in their shortened replicative lifespan. A number of different p38 MAPK inhibitor chemotypes have been prepared rapidly and efficiently using microwave heating techniques for biological study in Werner syndrome cells, including SB203580, VX-745, RO3201195, UR-13756 and BIRB 796, and their selectivity and potency evaluated in this cellular context. Werner syndrome fibroblasts treated with a p38 MAPK inhibitor reveal an unexpected reversal of the accelerated ageing phenotype. Thus the study of p38 inhibition and its effect upon Werner pathophysiology is likely to provide new revelations into the biological mechanisms operating in cellular senescence and human ageing in the future.

Alternate aircraft fuels prospects and operational implications

Science.gov (United States)

Witcofski, R. D.

1977-01-01

The paper discusses NASA studies of the potentials of coal-derived aviation fuels, specifically synthetic aviation kerosene, liquid methane, and liquid hydrogen. Topics include areas of fuel production, air terminal requirements for aircraft fueling (for liquid hydrogen only), and the performance characteristics of aircraft designed to utilize alternate fuels. Energy requirements associated with the production of each of the three selected fuels are determined, and fuel prices are estimated. Subsonic commercial air transports using liquid hydrogen fuel have been analyzed, and their performance and the performance of aircraft which use commercial aviation kerosene are compared. Environmental and safety issues are considered.

Cosmic radiation and airline pilots: Exposure pattern as a function of aircraft type

International Nuclear Information System (INIS)

Tveten, U.; Haldorsen, T.; Reitan, J.

2000-01-01

The project presented here has been carried out as part of an epidemiological project on Norwegian aircraft personnel, entitled 'Exposure to low level ionising radiation and incidence of cancer in airline pilots and crew'. The purpose of the main project is to determine if there may be a relationship between exposure to cosmic radiation at aircraft cruising altitudes and the incidence of cancer. The methodology used as basis for estimating the radiation exposures is presented. The information used as basis for the dose estimations comes from a variety of sources: the files at the Personnel Licensing Section and the Aviation Medical Section of Norwegian Aviation Administration, the route tables of Scandinavian Airlines System (SAS), large amounts of expert information contributed by members of the Pilot's Associations in Norway and a couple of non-Norwegian pilots and from other members of the staff of SAS and other airlines. The estimation for each pilot was based on individual information of annual block hours and an estimated dose rate for each type of aircraft. The latter was estimated as a weighted average of CARI-estimated doses on a selection of routes flown by the airplanes in the different time periods. The project includes all pilots that have been licensed in Norway since 1946. These pilots have been flying a large variety of different types of aircraft and routes. The cosmic radiation intensity is a function of altitude in the atmosphere and, less markedly, of geographical latitude and of the intensity of the radiation from the sun (quantified as the heliocentric potential). Different types of aircraft fly at different altitudes and are used for different purposes (passenger traffic, cargo, air photography, preparation of maps etc) and used on different routes. The end results of the project described in this article are radiation exposures per block hour for each type of aircraft, and for each individual year (the differences between years reflect the

Aircraft and background noise annoyance effects

Science.gov (United States)

Willshire, K. F.

1984-01-01

To investigate annoyance of multiple noise sources, two experiments were conducted. The first experiment, which used 48 subjects, was designed to establish annoyance-noise level functions for three community noise sources presented individually: jet aircraft flyovers, air conditioner, and traffic. The second experiment, which used 216 subjects, investigated the effects of background noise on aircraft annoyance as a function of noise level and spectrum shape; and the differences between overall, aircraft, and background noise annoyance. In both experiments, rated annoyance was the dependent measure. Results indicate that the slope of the linear relationship between annoyance and noise level for traffic is significantly different from that of flyover and air conditioner noise and that further research was justified to determine the influence of the two background noises on overall, aircraft, and background noise annoyance (e.g., experiment two). In experiment two, total noise exposure, signal-to-noise ratio, and background source type were found to have effects on all three types of annoyance. Thus, both signal-to-noise ratio, and the background source must be considered when trying to determine community response to combined noise sources.

Strategic Conflict Detection and Resolution Using Aircraft Intent Information

Science.gov (United States)

Porretta, Marco; Schuster, Wolfgang; Majumdar, Arnab; Ochieng, Washington

A number of automated decision support tools will be required in the future air traffic management system to enable continued provision of safe and efficient services in increasingly congested skies. In particular, Conflict Detection and Resolution (CDR) tools should allow for early detection of possible conflicts and propose safe and efficient resolution manoeuvres to avoid loss of separation. However, current approaches in the open literature not only use different levels of aircraft intent information but also make a number of assumptions on models of aircraft motion. Furthermore, information relevant to aircraft performance is often not considered with the consequence of the resulting resolution strategies being potentially unreliable. This paper presents an enhanced, strategic, pairwise, performance-based and distributed CDR algorithm. It accounts for the weaknesses of current approaches by using the maximum level of aircraft intent information together with a novel trajectory prediction model. Numerical results for representative conflict scenarios show that the proposed CDR method is able to generate conflict-free trajectories for participating aircraft while taking into account the actual aircraft capabilities to perform the recommended resolution manoeuvres.

Visit to China's ARJ21 Aircraft Manufacturing Facility

National Research Council Canada - National Science Library

Balut, Stephen J; McNicol, David L; Nelson, J. R; Harmon, Bruce R; Holder, Stephen G

2008-01-01

During a December 2007 visit to China to share information about civilian aircraft costs, a delegation from IDA visited the Shanghai Aircraft Manufacturing Facility where the commercial chinese ARJ21...

Modular Electric Propulsion Test Bed Aircraft, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — An all electric aircraft test bed is proposed to provide a dedicated development environment for the rigorous study and advancement of electrically powered aircraft....

Robotics and Automation for Flight Deck Aircraft Servicing

Energy Technology Data Exchange (ETDEWEB)

Chesser, J.B.; Draper, J.V.; Pin, F.G.

1999-03-01

One of the missions of the Future Aircraft Carriers Program is to investigate methods that would improve aircraft turnaround servicing activities on carrier decks. The major objectives and criteria for evaluating alternative aircraft servicing methods are to reduce workload requirements, turnaround times (TAT), and life-cycle costs (LCC). Technologies in the field of Robotics and Automation (R and A) have the potential to significantly contribute to these objectives. The objective of this study was to investigate aircraft servicing functions on carrier decks which would offer the potentially most significant payoff if improved by various R and A technologies. Improvement in this case means reducing workload, time and LCC. This objective was accomplished using a ''bottom-up'' formalized approach as described in the following.

The Selected Problems of Studies of Aircraft Landing Gear

Directory of Open Access Journals (Sweden)

Rośkowicz Marek

2016-12-01

Full Text Available The article portrays the results of experimental studies conducted in the field of static strength test of main landing gear of lightweight aircraft as well as in the area of establishing the pneumatic tyre characteristics of main landing gear. The studies were carried out in compliance with methodologies of performing studies for the purposes of solutions implemented in aviation structures. It was stated that static strength tests of landing gear should not be done with the use of shock absorbers, due to the fact that this element, distinguished by high viscoelastic properties, by being statically loaded, is subject to displacements that do not occur during normal operation of the aircraft. Excessive displacements of shock absorber result in the load distribution in other landing gear elements being incompatible with project assumptions, which in turn leads to this strength test being interrupted, bearing in mind significantly lower loads than anticipated. It was also concluded that in order to determine pneumatic tyre characteristics it is not necessary to carry out tests on the whole landing gear strut, because the results obtained in the compression test of the wheel itself with pneumatic tyre are identical as the results acquired during tests conducted in accordance with methodology. Test preparation process with the use of the wheel itself and its realization is less time-consuming, less expensive and does not entail the necessity to build complex test stands.

Model of aircraft noise adaptation

Science.gov (United States)

Dempsey, T. K.; Coates, G. D.; Cawthorn, J. M.

1977-01-01

Development of an aircraft noise adaptation model, which would account for much of the variability in the responses of subjects participating in human response to noise experiments, was studied. A description of the model development is presented. The principal concept of the model, was the determination of an aircraft adaptation level which represents an annoyance calibration for each individual. Results showed a direct correlation between noise level of the stimuli and annoyance reactions. Attitude-personality variables were found to account for varying annoyance judgements.

Seat Capacity Selection for an Advanced Short-Haul Aircraft Design

Science.gov (United States)

Marien, Ty V.

2016-01-01

A study was performed to determine the target seat capacity for a proposed advanced short-haul aircraft concept projected to enter the fleet by 2030. This analysis projected the potential demand in the U.S. for a short-haul aircraft using a transportation theory approach, rather than selecting a target seat capacity based on recent industry trends or current market demand. A transportation systems model was used to create a point-to-point network of short-haul trips and then predict the number of annual origin-destination trips on this network. Aircraft of varying seat capacities were used to meet the demand on this network, assuming a single aircraft type for the entire short-haul fleet. For each aircraft size, the ticket revenue and operational costs were used to calculate a total market profitability metric for all feasible flights. The different aircraft sizes were compared, based on this market profitability metric and also the total number of annual round trips and markets served. Sensitivity studies were also performed to determine the effect of changing the aircraft cruise speed and maximum trip length. Using this analysis, the advanced short-haul aircraft design team was able to select a target seat capacity for their design.

Aircraft dynamic loads generated in wake vortex encounters

OpenAIRE

Suñer Perucho, Carles

2014-01-01

The study illustrated in these pages was developed in the Structural Dynamics and Aeroelasticity Department of the Military Aircraft division of Airbus Defence and Space in Getafe, Madrid (Spain). That department is a multidisciplinary one involving several categories. Some of its competences are the analysis of impacts, acoustics and vibrations for the aircraft and all their systems. Also, the dynamic response of the aircraft to different events is part of the tasks for that department. It i...

Wind Information Uplink to Aircraft Performing Interval Management Operations

Science.gov (United States)

Ahmad, Nashat N.; Barmore, Bryan E.; Swieringa, Kurt A.

2016-01-01

Interval Management (IM) is an ADS-B-enabled suite of applications that use ground and flight deck capabilities and procedures designed to support the relative spacing of aircraft (Barmore et al., 2004, Murdoch et al. 2009, Barmore 2009, Swieringa et al. 2011; Weitz et al. 2012). Relative spacing refers to managing the position of one aircraft to a time or distance relative to another aircraft, as opposed to a static reference point such as a point over the ground or clock time. This results in improved inter-aircraft spacing precision and is expected to allow aircraft to be spaced closer to the applicable separation standard than current operations. Consequently, if the reduced spacing is used in scheduling, IM can reduce the time interval between the first and last aircraft in an overall arrival flow, resulting in increased throughput. Because IM relies on speed changes to achieve precise spacing, it can reduce costly, low-altitude, vectoring, which increases both efficiency and throughput in capacity-constrained airspace without negatively impacting controller workload and task complexity. This is expected to increase overall system efficiency. The Flight Deck Interval Management (FIM) equipment provides speeds to the flight crew that will deliver them to the achieve-by point at the controller-specified time, i.e., assigned spacing goal, after the target aircraft crosses the achieve-by point (Figure 1.1). Since the IM and target aircraft may not be on the same arrival procedure, the FIM equipment predicts the estimated times of arrival (ETA) for both the IM and target aircraft to the achieve-by point. This involves generating an approximate four-dimensional trajectory for each aircraft. The accuracy of the wind data used to generate those trajectories is critical to the success of the IM operation. There are two main forms of uncertainty in the wind information used by the FIM equipment. The first is the accuracy of the forecast modeling done by the weather

Rankine-Brayton engine powered solar thermal aircraft

Science.gov (United States)

Bennett, Charles L [Livermore, CA

2009-12-29

A solar thermal powered aircraft powered by heat energy from the sun. A Rankine-Brayton hybrid cycle heat engine is carried by the aircraft body for producing power for a propulsion mechanism, such as a propeller or other mechanism for enabling sustained free flight. The Rankine-Brayton engine has a thermal battery, preferably containing a lithium-hydride and lithium mixture, operably connected to it so that heat is supplied from the thermal battery to a working fluid. A solar concentrator, such as reflective parabolic trough, is movably connected to an optically transparent section of the aircraft body for receiving and concentrating solar energy from within the aircraft. Concentrated solar energy is collected by a heat collection and transport conduit, and heat transported to the thermal battery. A solar tracker includes a heliostat for determining optimal alignment with the sun, and a drive motor actuating the solar concentrator into optimal alignment with the sun based on a determination by the heliostat.

Rankline-Brayton engine powered solar thermal aircraft

Science.gov (United States)

Bennett, Charles L [Livermore, CA

2012-03-13

A solar thermal powered aircraft powered by heat energy from the sun. A Rankine-Brayton hybrid cycle heat engine is carried by the aircraft body for producing power for a propulsion mechanism, such as a propeller or other mechanism for enabling sustained free flight. The Rankine-Brayton engine has a thermal battery, preferably containing a lithium-hydride and lithium mixture, operably connected to it so that heat is supplied from the thermal battery to a working fluid. A solar concentrator, such as reflective parabolic trough, is movably connected to an optically transparent section of the aircraft body for receiving and concentrating solar energy from within the aircraft. Concentrated solar energy is collected by a heat collection and transport conduit, and heat transported to the thermal battery. A solar tracker includes a heliostat for determining optimal alignment with the sun, and a drive motor actuating the solar concentrator into optimal alignment with the sun based on a determination by the heliostat.

Access improvement to aircraft passengers' hand luggage.

Science.gov (United States)

Alberda, W; Kampinga, O; Kassels, R; van Kester, R; Noriega, J; Vink, P

2015-01-01

Efficient use of space and passenger comfort in aircraft interiors are major issues. There is not much research available about the flying experience regarding passengers' personal belongings. The objective of this study is to explore concepts within the current aircraft seats which improve the passenger experience related to their personal belongings like wallets, mobile phones and laptops. Through on-site observations, interviews and online questionnaires, data regarding the number of personal belongings taken into the airplane and opinions about access to hand luggage were gathered. These data were used to develop different concepts to optimize the aircraft interior, which were evaluated by passengers. Almost every passenger carries a phone (88%), wallet (94%), travel documents (98%) and keys (76%) with them and they like to have these stored close by. Passengers rate the concept that provides integrated storage in the tray table of the aircraft seat the best. Extra storage possibility in the table-tray seems a promising solution according to the passengers.

MD-11 PCA - View of aircraft on ramp

Science.gov (United States)

1995-01-01

This McDonnell Douglas MD-11 is taxiing to a position on the flightline at NASA's Dryden Flight Research Center, Edwards, California, following its completion of the first and second landings ever performed by a transport aircraft under engine power only (on Aug. 29, 1995). The milestone flight, with NASA research pilot and former astronaut Gordon Fullerton at the controls, was part of a NASA project to develop a computer-assisted engine control system that enables a pilot to land a plane safely when its normal control surfaces are disabled. The Propulsion-Controlled Aircraft (PCA) system uses standard autopilot controls already present in the cockpit, together with the new programming in the aircraft's flight control computers. The PCA concept is simple. For pitch control, the program increases thrust to climb and reduces thrust to descend. To turn right, the autopilot increases the left engine thrust while decreasing the right engine thrust. The initial Propulsion-Controlled Aircraft studies by NASA were carried out at Dryden with a modified twin-engine F-15 research aircraft.

Determination of tricresyl phosphate air contamination in aircraft.

Science.gov (United States)

Denola, G; Hanhela, P J; Mazurek, W

2011-08-01

Monitoring of tricresyl phosphate (TCP) contamination of cockpit air was undertaken in three types of military aircraft [fighter trainer (FT), fighter bomber (FB), and cargo transport (CT) aircraft]. The aircraft had a previous history of pilot complaints about cockpit air contamination suspected to originate from the engine bleed air supply through the entry of aircraft turbine engine oil (ATO) into the engine compressor. Air samples were collected in flight and on the ground during engine runs using sorbent tubes packed with Porapak Q and cellulose filters. A total of 78 air samples were analysed, from 46 different aircraft, and 48 samples were found to be below the limit of detection. Nine incidents of smoke/odour were identified during the study. The concentrations of toxic o-cresyl phosphate isomers were below the level of detection in all samples. The highest total TCP concentration was 51.3 μg m(-3), while most were generally found to be contamination of cabin/cockpit air has been the subject of much concern in aviation, quantitative data are sparse.

A manpower scheduling heuristic for aircraft maintenance application

Science.gov (United States)

Sze, San-Nah; Sze, Jeeu-Fong; Chiew, Kang-Leng

2012-09-01

This research studies a manpower scheduling for aircraft maintenance, focusing on in-flight food loading operation. A group of loading teams with flexible shifts is required to deliver and upload packaged meals from the ground kitchen to aircrafts in multiple trips. All aircrafts must be served within predefined time windows. The scheduling process takes into account of various constraints such as meal break allocation, multi-trip traveling and food exposure time limit. Considering the aircrafts movement and predefined maximum working hours for each loading team, the main objective of this study is to form an efficient roster by assigning a minimum number of loading teams to the aircrafts. We proposed an insertion based heuristic to generate the solutions in a short period of time for large instances. This proposed algorithm is implemented in various stages for constructing trips due to the presence of numerous constraints. The robustness and efficiency of the algorithm is demonstrated in computational results. The results show that the insertion heuristic more efficiently outperforms the company's current practice.

ESCOMPTE experiment: intercomparison of four aircraft dynamical, thermodynamical, radiation and chemical measurements

Science.gov (United States)

Saïd, F.; Corsmeier, U.; Kalthoff, N.; Kottmeier, C.; Lothon, M.; Wieser, A.; Hofherr, T.; Perros, P.

2005-03-01

Among seven airplanes involved in the Experience sur Site pour COntraindre les Modèles de Pollution atmosphérique et de Transport d'Emission (ESCOMPTE) experiment in 2001, four measured classical meteorological parameters, radiation fluxes, trace gases and turbulence (for three among four): the Dornier 128 from the Institut für Meteorologie und Klimaforschung, the Fokker 27 ARAT from the Institut National des Sciences de l'Univers, the Merlin 4 and Piper Aztec 23 from Météo France. This paper presents the results of intercomparison flights between three pairs of aircraft. The results are very similar for mean parameters except for the horizontal wind measurements provided by the Merlin that showed a problem that is probably linked to the measurement of the aircraft velocity. Further investigation is required to know whether corrections are possible or not for these wind measurements. Turbulence is studied along two legs over a flat and homogeneous area: in spite of the heterogeneity of the measured functions (one leg is close to the top of the boundary layer), the comparison is rather good. The relative accuracy of the data provided to the data base is given. It easily allows to use the huge amount of aircraft data collected during the experiment with very few restrictions. We underline some points where efforts should be borne for future experiments: wind coupling between Inertial Navigation System data and Global Positioning System (GPS) data, CO and NO x measurements.

Study of LH2 fueled subsonic passenger transport aircraft

Science.gov (United States)

Brewer, G. D.; Morris, R. E.

1976-01-01

The potential of using liquid hydrogen as fuel in subsonic transport aircraft was investigated to explore an expanded matrix of passenger aircraft sizes. Aircraft capable of carrying 130 passengers 2,780 km (1500 n.mi.); 200 passengers 5,560 km (3000 n.mi.); and 400 passengers on a 9,265 km (5000 n.mi.) radius mission, were designed parametrically. Both liquid hydrogen and conventionally fueled versions were generated for each payload/range in order that comparisons could be made. Aircraft in each mission category were compared on the basis of weight, size, cost, energy utilization, and noise.

Judgments of aircraft noise in a traffic noise background

Science.gov (United States)

Powell, C. A.; Rice, C. G.

1975-01-01

An investigation was conducted to determine subjective response to aircraft noise in different road traffic backgrounds. In addition, two laboratory techniques for presenting the aircraft noise with the background noise were evaluated. For one technique, the background noise was continuous over an entire test session; for the other, the background noise level was changed with each aircraft noise during a session. Subjective response to aircraft noise was found to decrease with increasing background noise level, for a range of typical indoor noise levels. Subjective response was found to be highly correlated with the Noise Pollution Level (NPL) measurement scale.

Intelligent Aircraft Damage Assessment, Trajectory Planning, and Decision-Making under Uncertainty

Science.gov (United States)

Lopez, Israel; Sarigul-Klijn, Nesrin

Situational awareness and learning are necessary to identify and select the optimal set of mutually non-exclusive hypothesis in order to maximize mission performance and adapt system behavior accordingly. This paper presents a hierarchical and decentralized approach for integrated damage assessment and trajectory planning in aircraft with uncertain navigational decision-making. Aircraft navigation can be safely accomplished by properly addressing the following: decision-making, obstacle perception, aircraft state estimation, and aircraft control. When in-flight failures or damage occur, rapid and precise decision-making under imprecise information is required in order to regain and maintain control of the aircraft. To achieve planned aircraft trajectory and complete safe landing, the uncertainties in system dynamics of the damaged aircraft need to be learned and incorporated at the level of motion planning. The damaged aircraft is simulated via a simplified kinematic model. The different sources and perspectives of uncertainties in the damage assessment process and post-failure trajectory planning are presented and classified. The decision-making process for an emergency motion planning and landing is developed via the Dempster-Shafer evidence theory. The objective of the trajectory planning is to arrive at a target position while maximizing the safety of the aircraft given uncertain conditions. Simulations are presented for an emergency motion planning and landing that takes into account aircraft dynamics, path complexity, distance to landing site, runway characteristics, and subjective human decision.

Advanced energy systems (APU) for large commercial aircraft

Energy Technology Data Exchange (ETDEWEB)

Westenberger, A.; Bleil, J.; Arendt, M. [Airbus Deutschland GmbH, Hamburg (Germany)

2013-06-01

The intention of using a highly integrated component using on fuel cell technology installed on board of large commercial passenger aircraft for the generation of onboard power for the systems demand during an entire aircraft mission was subject of several studies. The results of these studies have been based on the simulation of the whole system in the context of an aircraft system environment. In front of the work stood the analyses of different fuel cell technologies and the analyses of the aircraft system environment. Today onboard power is provided on ground by an APU and in flight by the main engines. In order to compare fuel cell technology with the today's usual gas turbine operational characteristics have been analysed. A second analysis was devoted to the system demand for typical aircraft categories. The MEA system concept was supposed in all cases. The favourable concept represented an aircraft propelled by conventional engines with starter generator units, providing AC electrical power, covering in total proximately half of the power demand and a component based on fuel cell technology. This component provided electrical DC power, clean potable water, thermal energy at 180 degrees Celsius and nitrogen enriched air for fire suppression and fire extinguishing agent. In opposite of a usual gas turbine based APU, this new unit was operated as the primary power system. (orig.)

Robust Control of an Ill-Conditioned Aircraft

DEFF Research Database (Denmark)

Breslin, S.G.; Tøffner-Clausen, S.; Grimble, M.J.

1996-01-01

A robust controller is designed for a linear model of an Advanced Short Take-Off and Vertical Landing (ASTOVL) aircraft at one operating point.......A robust controller is designed for a linear model of an Advanced Short Take-Off and Vertical Landing (ASTOVL) aircraft at one operating point....

Stability Result For Dynamic Inversion Devised to Control Large Flexible Aircraft

Science.gov (United States)

Gregory, Irene M.

2001-01-01

High performance aircraft of the future will be designed lighter, more maneuverable, and operate over an ever expanding flight envelope. One of the largest differences from the flight control perspective between current and future advanced aircraft is elasticity. Over the last decade, dynamic inversion methodology has gained considerable popularity in application to highly maneuverable fighter aircraft, which were treated as rigid vehicles. This paper is an initial attempt to establish global stability results for dynamic inversion methodology as applied to a large, flexible aircraft. This work builds on a previous result for rigid fighter aircraft and adds a new level of complexity that is the flexible aircraft dynamics, which cannot be ignored even in the most basic flight control. The results arise from observations of the control laws designed for a new generation of the High-Speed Civil Transport aircraft.

Depreciation of aircraft

Science.gov (United States)

Warner, Edward P

1922-01-01

There is a widespread, and quite erroneous, impression to the effect that aircraft are essentially fragile and deteriorate with great rapidity when in service, so that the depreciation charges to be allowed on commercial or private operation are necessarily high.

T1- Thresholds in Black Holes Increase Clinical-Radiological Correlation in Multiple Sclerosis Patients.

Science.gov (United States)

Thaler, Christian; Faizy, Tobias; Sedlacik, Jan; Holst, Brigitte; Stellmann, Jan-Patrick; Young, Kim Lea; Heesen, Christoph; Fiehler, Jens; Siemonsen, Susanne

2015-01-01

Magnetic Resonance Imaging (MRI) is an established tool in diagnosing and evaluating disease activity in Multiple Sclerosis (MS). While clinical-radiological correlations are limited in general, hypointense T1 lesions (also known as Black Holes (BH)) have shown some promising results. The definition of BHs is very heterogeneous and depends on subjective visual evaluation. We aimed to improve clinical-radiological correlations by defining BHs using T1 relaxation time (T1-RT) thresholds to achieve best possible correlation between BH lesion volume and clinical disability. 40 patients with mainly relapsing-remitting MS underwent MRI including 3-dimensional fluid attenuated inversion recovery (FLAIR), magnetization-prepared rapid gradient echo (MPRAGE) before and after Gadolinium (GD) injection and double inversion-contrast magnetization-prepared rapid gradient echo (MP2RAGE) sequences. BHs (BHvis) were marked by two raters on native T1-weighted (T1w)-MPRAGE, contrast-enhancing lesions (CE lesions) on T1w-MPRAGE after GD and FLAIR lesions (total-FLAIR lesions) were detected separately. BHvis and total-FLAIR lesion maps were registered to MP2RAGE images, and the mean T1-RT were calculated for all lesion ROIs. Mean T1 values of the cortex (CTX) were calculated for each patient. Subsequently, Spearman rank correlations between clinical scores (Expanded Disability Status Scale and Multiple Sclerosis Functional Composite) and lesion volume were determined for different T1-RT thresholds. Significant differences in T1-RT were obtained between all different lesion types with highest T1 values in visually marked BHs (BHvis: 1453.3±213.4 ms, total-FLAIR lesions: 1394.33±187.38 ms, CTX: 1305.6±35.8 ms; p1500 ms (Expanded Disability Status Scale vs. lesion volume: rBHvis = 0.442 and rtotal-FLAIR = 0.497, p<0.05; Multiple Sclerosis Functional Composite vs. lesion volume: rBHvis = -0.53 and rtotal-FLAIR = -0.627, p<0.05). Clinical-radiological correlations in MS patients are

F-15 PCA (Propulsion Controlled Aircraft) Simulation Cockpit

Science.gov (United States)

1990-01-01

The F-15 PCA (Propulsion Controlled Aircraft) simulation was used from 1990 to 1993. It was used for the development of propulsion algorithms and piloting techniques (using throttles only) to be used for emergency flight control in the advent of a major flight control system failure on a multi-engine aircraft. Following this program with the Dryden F-15, similiar capabilities were developed for other aircraft, such as the B-720, Lear 24, B-727, C-402, and B-747.

77 FR 45480 - Deductions for Entertainment Use of Business Aircraft

Science.gov (United States)

2012-08-01

... Deductions for Entertainment Use of Business Aircraft AGENCY: Internal Revenue Service (IRS), Treasury... business aircraft for entertainment. These final regulations affect taxpayers that deduct expenses for... section 274 of the Internal Revenue Code (Code) of deductions for the use of business aircraft for...

Aerodynamics/ACEE: Aircraft energy efficiency

Science.gov (United States)

1981-01-01

An overview is presented of a 10 year program managed by NASA which seeks to make possible the most efficient use of energy for aircraft propulsion and lift as well as provide a technology that can be used by U.S. manufacturers of air transports and engines. Supercritical wings, winglets, vortex drag reduction, high lift, active control, laminar flow control, and aerodynamics by computer are among the topics discussed. Wind tunnel models in flight verification of advanced technology, and the design, construction and testing of various aircraft structures are also described.

Multidisciplinary Techniques and Novel Aircraft Control Systems

Science.gov (United States)

Padula, Sharon L.; Rogers, James L.; Raney, David L.

2000-01-01

The Aircraft Morphing Program at NASA Langley Research Center explores opportunities to improve airframe designs with smart technologies. Two elements of this basic research program are multidisciplinary design optimization (MDO) and advanced flow control. This paper describes examples where MDO techniques such as sensitivity analysis, automatic differentiation, and genetic algorithms contribute to the design of novel control systems. In the test case, the design and use of distributed shape-change devices to provide low-rate maneuvering capability for a tailless aircraft is considered. The ability of MDO to add value to control system development is illustrated using results from several years of research funded by the Aircraft Morphing Program.

Assessment of NDE needs for aging corporate and private aircraft

Science.gov (United States)

Reinhart, Eugene R.

1998-03-01

Considerable attention has been focused on the life extension of ageing military and commercial aircraft by the government and major aircraft fabricators. A vital, but often neglected segment of the aircraft industry is the are of inspecting ageing fleets of corporate and privately-owned aircraft. Many of these aircraft are inspected and maintained by the various FAA-approved repair stations located around the country. Nondestructive inspection (NDI) methods, equipment, and trained inspectors are a key aspect of maintaining these aircraft; however, there are currently several issues that need to be addressed by the private sector NDI community. Personnel training and certification to an accepted standard is critically needed in this industry since experience and capability in NDI can vary considerably between FAA stations and inspectors. Also, the updating of NDI methods are standards is needed. A review of these issues and suggestions for improvement are presented.

Aircraft Anomaly Detection Using Performance Models Trained on Fleet Data

Science.gov (United States)

Gorinevsky, Dimitry; Matthews, Bryan L.; Martin, Rodney

2012-01-01

This paper describes an application of data mining technology called Distributed Fleet Monitoring (DFM) to Flight Operational Quality Assurance (FOQA) data collected from a fleet of commercial aircraft. DFM transforms the data into aircraft performance models, flight-to-flight trends, and individual flight anomalies by fitting a multi-level regression model to the data. The model represents aircraft flight performance and takes into account fixed effects: flight-to-flight and vehicle-to-vehicle variability. The regression parameters include aerodynamic coefficients and other aircraft performance parameters that are usually identified by aircraft manufacturers in flight tests. Using DFM, the multi-terabyte FOQA data set with half-million flights was processed in a few hours. The anomalies found include wrong values of competed variables, (e.g., aircraft weight), sensor failures and baises, failures, biases, and trends in flight actuators. These anomalies were missed by the existing airline monitoring of FOQA data exceedances.

Cycle Counting Methods of the Aircraft Engine

Science.gov (United States)

Fedorchenko, Dmitrii G.; Novikov, Dmitrii K.

2016-01-01

The concept of condition-based gas turbine-powered aircraft operation is realized all over the world, which implementation requires knowledge of the end-of-life information related to components of aircraft engines in service. This research proposes an algorithm for estimating the equivalent cyclical running hours. This article provides analysis…

14 CFR 13.17 - Seizure of aircraft.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Seizure of aircraft. 13.17 Section 13.17... INVESTIGATIVE AND ENFORCEMENT PROCEDURES Legal Enforcement Actions § 13.17 Seizure of aircraft. (a) Under... officer, or a Federal Aviation Administration safety inspector, authorized in an order of seizure issued...

38 CFR 3.363 - Bar to benefits under 38 U.S.C. 1151.

Science.gov (United States)

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Bar to benefits under 38... Purposes § 3.363 Bar to benefits under 38 U.S.C. 1151. (a) Claims subject to this section. This section.... (b) Administrative award, compromises, or settlements, or judgments that bar benefits under 38 U.S.C...

The community response to aircraft noise around six Spanish airports

Science.gov (United States)

Garcia, A.; Faus, L. J.; Garcia, A. M.

1993-06-01

The community response to aircraft noise has been studied through a social survey. A total of 1800 persons living in the vicinity of six major Spanish airports have been interviewed at their homes concerning the environmental quality of the area, dissatisfaction with road traffic noise and aircraft noise, activities interfered with by noise, most disturbing aircraft types, and subjective evaluation of airport impact. All the responses obtained in this survey have been compared with aircraft noise levels corresponding to the residence locations of the people interviewed (values of NEF levels were calculated with the INM model). The results obtained in this work allow one to evaluate the impact of aircraft noise under a wide range of different situations.

Preparation of quality control samples for thyroid hormones T3 and T4 in radioimmunoassay techniques

International Nuclear Information System (INIS)

Ahmed, F.O.A.

2006-03-01

Today, the radioimmunoassay becomes one of the best techniques for quantitative analysis of very low concentration of different substances. RIA is being widely used in medical and research laboratories. To maintain high specificity and accuracy in RIA and other related techniques the quality controls must be introduced. In this dissertation quality control samples for thyroid hormones (Triiodothyronine T3 and Thyroxin T4), using RIA techniques. Ready made chinese T4, T3 RIA kits were used. IAEA statistical package were selected.(Author)

Laser surgery combined with radiotherapy for T1/T2 hypopharyngeal squamous cell carcinomas

International Nuclear Information System (INIS)

Sakamoto, Kikuo; Nakashima, Tadashi

2006-01-01

We analyzed the results and clinical features of 41 patients with T1 or T2 squamous cell carcinoma of the hypopharynx who received the treatment of laser surgery combined with radiotherapy at the Kurume University Hospital between 1989 and 2003. The patients consisted of 38 males and 3 females (mean age: 64 years); T classification was 8 T1 cases and 33 T2 cases. N classification of the patients was 20 N0 cases, 9 N1 cases, 10 N2 cases, and 2 N3 cases. Three were stage I, 17 were stage II, 9 were stage III, and 12 were stage IV. Sub-sites of the tumor were 33 of piriform sinus type, 6 of post-cricoid type and 2 of poterior wall type. The primary disease was treated by laser debulking surgery combined with radiotherapy. Local recurrence was recognized in 4 cases and laryngectomy was performed in 3 cases. As a result, 38 (92.6%) cases were treated by preserving the larynx. All patients could eat a meal from the day following the operation. Tracheostomy was performed in six cases, but the tracheal stoma could be closed in five. The disease-specific 5-year survival rate was 87.7%. The 5-year local control rate was 90.2%. The overall 5-year survival rate was 49.2%. Four patients died of the primary disease (lymph node death: 3, distant metastasis death: 1). This retrospective review indicates that laser debulking surgery combined with radiotherapy is a successful treatment for T1/T2 hypopharyngeal carcinoma. (author)

Aircraft Crash Survival Design Guide. Volume 5. Aircraft Postcrash Survival

Science.gov (United States)

1980-01-01

neck Access door toprille capm enrFuel tank Figue 3. Fangblefiler eckinsalgbelati n. A-j L)n wal Aircraft skin Frangible filler neck Failure plane...This is because a number of major assumptions must be made in the extrapolation: the smoke generated is uniformly distri- buted and is independent

Liens on aircraft with special reference on statutory liens

Directory of Open Access Journals (Sweden)

Janković Svetislav

2014-01-01

Full Text Available The paper examines three types of liens on aircraft: mortgage (as contractual lien, statutory and judicial lien on aircraft. Special attention is paid to statutory liens and its relationship with mortgage and judicial lien on same aircraft. The author highlights the problem of priority of different type of secured creditors due to the fact of existing competition between their interests. This problem is especially enlarged because of simultaneously applying three different source of law: Cape Town Convention 2001, Serbian Law of Air Transport 2011 and Geneva Convention on the Recognition of Rights in Aircraft 1948. Conclusion is that the creditor with statutory lien on aircraft has the biggest priority in realization of his right over other creditors and even creditors secured with mortgage and judicial lien which have priority between themselves in comply with principle 'first in time, first in right'. In order to achieve the ideas of this conclusion in practice it is necessary for courts to use teleological interpretation in applying laws. This is especially because of certain inconsistencies between different legal sources in regard of notion, order of priority and effect of different type of liens on aircraft.

Inhalation toxicology. I., Design of a small-animal test system, II. Determination of the relative toxic hazards of 75 aircraft cabin materials.

Science.gov (United States)

1977-01-01

In an effort to further the cause of increased safety for those who ride in commercial aircraft, this paper presents a detailed description of the genesis of a small-scale, laboratory test system that utilizes small animals to evaluate the relative t...

Energy optimization analysis of the more electric aircraft

Science.gov (United States)

Liu, Yitao; Deng, Junxiang; Liu, Chao; Li, Sen

2018-02-01

The More Electric Aircraft (MEA) underlines the utilization of the electrical power to drive the non-propulsive aircraft systems. The critical features of the MEA including no-bleed engine architecture and advanced electrical system are introduced. Energy and exergy analysis is conducted for the MEA, and comparison of the effectiveness and efficiency of the energy usage between conventional aircraft and the MEA is conducted. The results indicate that one of the advantages of the MEA architecture is the greater efficiency gained in terms of reduced fuel consumption.

Weed detection using unmanned aircraft vehicles

Directory of Open Access Journals (Sweden)

Pflanz, Michael

2014-03-01

Full Text Available In contrast to agricultural remote sensing technologies, which are based on images from satellites or manned aircrafts, photogrammetry at low altitude from unmanned aircraft vehicles lead to higher spatial resolution, real-time processing and lower costs. Moreover multicopter aircrafts are suitable vehicles to perform precise path or stationary flights. In terms of vegetation photogrammetry this minimises motion blur and provide better image overlapping for stitching and mapping procedures. Through improved image analyses and through the recent increase in the availability of powerful batteries, microcontrollers and multispectral cameras, it can be expected in future that spatial mapping of weeds from low altitudes will be promoted. A small unmanned aircraft vehicle with a modified RGB camera was tested taking images from agricultural fields. A microcopter with six rotors was applied. The hexacopter in particular is GPS controlled and operates within predefined areas at given altitudes (from 5 to 10 m. Different scenarios of photogrammetrically weed detection have been carried out regarding to variable altitude, image resolution, weed and crop growth stages. First experiences with microcopter showed a high potential for site-specific weed control. Images analyses with regards to recognition of weed patches can be used to adapt herbicide applications to varying weed occurrence across a field.

Unmanned Aircraft Systems: The Road to Effective Integration

National Research Council Canada - National Science Library

Petrock, Christopher T; Huizenga, Thomas D

2006-01-01

...) sharing airspace with manned assets. There have been at least two recent collisions between unmanned and rotary-wing aircraft at lower altitudes in Iraq, as well as numerous near misses with fixed-wing aircraft at higher altitudes...

ViDiT-CACTUS: an inexpensive and versatile library preparation and sequence analysis method for virus discovery and other microbiology applications.

Science.gov (United States)

Verhoeven, Joost Theo Petra; Canuti, Marta; Munro, Hannah J; Dufour, Suzanne C; Lang, Andrew S

2018-04-19

High-throughput sequencing (HTS) technologies are becoming increasingly important within microbiology research, but aspects of library preparation, such as high cost per sample or strict input requirements, make HTS difficult to implement in some niche applications and for research groups on a budget. To answer these necessities, we developed ViDiT, a customizable, PCR-based, extremely low-cost (90% coverage), and the characterization and functional profiling of the complete microbial diversity (bacteria, archaea, viruses) within a deep-sea carnivorous sponge. ViDiT-CACTUS demonstrated its validity in a wide range of microbiology applications and its simplicity and modularity make it easily implementable in any molecular biology laboratory, towards various research goals.

Coarse to fine aircraft detection from front-looking infrared images

Science.gov (United States)

Lin, Jin; Tan, Yihua; Tian, Jinwen

2018-03-01

Due to the weak feature and wide angle of long-distance aircraft targeting in the parking apron from front-looking infrared images, there are always false alarms in aircraft targeting detection. This leads to relatively poor reliability for detection results. In this paper, we present a scene-driven coarse-to-fine aircraft target detection method. First, we preprocess the image by combining the sharpened and enhanced images. Second, the region of interest (ROI) is segmented by using the local mean variance of the image and a series of subsequent processing. Then, target candidate areas are located by using the feature of local marginal distributions. Lastly, aircrafts can be detected accurately by a novel aircraft shape filter. Experiments on three infrared image sequences have shown that the presented method is effective and robust in detecting long-distance aircraft from front-looking infrared images and can also improve the reliability of the detection results.

76 FR 6525 - Airworthiness Directives; Cessna Aircraft Company (Type Certificate Previously Held by Columbia...

Science.gov (United States)

2011-02-07

... Airworthiness Directives; Cessna Aircraft Company (Type Certificate Previously Held by Columbia Aircraft... following new AD: 2011-03-04 Cessna Aircraft Company (Type Certificate Previously Held by Columbia Aircraft... the following Cessna Aircraft Company (type certificate previously held by Columbia Aircraft...

Improvement of Aircraft Crash Effective Areas for Koeberg Nuclear Power Plant

International Nuclear Information System (INIS)

Momoti, S.; Dongmo, G.B.; Combrink, Y.

2017-01-01

Probabilistic Safety Assessment (PSA): Tool for determining safe functioning of nuclear power plant to meet regulatory requirements; One of the inputs to the PSA are the frequency and consequences of an aircraft crash. Overview: Frequency of Aircraft Crash; Effective Area of an Aircraft Crashing into Koeberg - Aviation Categories, - Shielding of sensitive target buildings; Impact of refining the Effective AreaFrequency of Aircraft Crash

Aircraft Fire Protection Laboratory

Data.gov (United States)

Federal Laboratory Consortium — The Navy Aircraft Protection Laboratory provides complete test support for all Navy air vehicle fire protection systems.The facility allows for the simulation of a...

The Impact of Rising Temperatures on Aircraft Takeoff Performance

Science.gov (United States)

Coffel, E.; Horton, R. M.; Thompson, T. R.

2017-12-01

Steadily rising mean and extreme temperatures as a result of climate change will likely impact the air transportation system over the coming decades. As air temperatures rise at constant pressure, air density declines, resulting in less lift generation by an aircraft wing at a given airspeed and potentially imposing a weight restriction on departing aircraft. This study presents a general model to project future weight restrictions across a fleet of aircraft with different takeoff weights operating at a variety of airports. We construct performance models for five common commercial aircraft and 19 major airports around the world and use projections of daily temperatures from the CMIP5 model suite under the RCP 4.5 and RCP 8.5 emissions scenarios to calculate required hourly weight restriction. We find that on average, 10-30% of annual flights departing at the time of daily maximum temperature may require some weight restriction below their maximum takeoff weights, with mean restrictions ranging from 0.5 to 4% of total aircraft payload and fuel capacity by mid- to late century. Both mid-sized and large aircraft are affected, and airports with short runways and high tempera- tures, or those at high elevations, will see the largest impacts. Our results suggest that weight restriction may impose a non-trivial cost on airlines and impact aviation operations around the world and that adaptation may be required in aircraft design, airline schedules, and/or runway lengths.

Damage assessment of nuclear containment against aircraft crash

Energy Technology Data Exchange (ETDEWEB)

Iqbal, Mohd Ashraf, E-mail: iqbal_ashraf@rediffmail.com; Sadique, Md. Rehan, E-mail: rehan.sadique@gmail.com; Bhargava, Pradeep, E-mail: bhpdpfce@iitr.ac.in; Bhandari, N.M., E-mail: nmbcefce@iitr.ac.in

2014-10-15

Highlights: • Damage assessment of nuclear containment is studied against aircraft crash. • Four impact locations have been identified at the outer containment shell. • The mid of the total height has been found to be most vulnerable location. • The crown of dome has been found to be the strongest location. • Phantom F4 caused more localized and severe damage compared to other aircrafts. - Abstract: The behavior of nuclear containment structure has been studied against aircraft crash with an emphasis on the influence of strike location. The impact locations identified on the BWR Mark III type nuclear containment structure are mid-height, junction of dome and cylinder, crown of dome and arc of dome. The containment at each of the above locations has been impacted normally by Phantom F-4, Boeing 707-320 and Airbus A320 aircrafts. The loading of the aircraft has been assigned through the corresponding reaction-time response curve. ABAQUS/Explicit finite element code has been used to carry out the three-dimensional numerical simulations. The concrete damaged plasticity model was used to simulate the behavior of concrete while the behavior of steel reinforcement was incorporated using the Johnson–Cook elasto-viscoplastic material model. The mid-height of containment has been found to experience most severe deformation against each aircraft. Phantom F4 has been found to be most disastrous at each location. The results have been compared with those of the available studies with respect to the containment deformation.

75 FR 8427 - Civil Supersonic Aircraft Panel Discussion

Science.gov (United States)

2010-02-24

... entitled, ``State of the Art of Supersonics Aircraft Technology--What has progressed in science since 1973... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Civil Supersonic Aircraft Panel Discussion AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of meeting participation...

Comprehensive analysis of transport aircraft flight performance

Science.gov (United States)

Filippone, Antonio

2008-04-01

This paper reviews the state-of-the art in comprehensive performance codes for fixed-wing aircraft. The importance of system analysis in flight performance is discussed. The paper highlights the role of aerodynamics, propulsion, flight mechanics, aeroacoustics, flight operation, numerical optimisation, stochastic methods and numerical analysis. The latter discipline is used to investigate the sensitivities of the sub-systems to uncertainties in critical state parameters or functional parameters. The paper discusses critically the data used for performance analysis, and the areas where progress is required. Comprehensive analysis codes can be used for mission fuel planning, envelope exploration, competition analysis, a wide variety of environmental studies, marketing analysis, aircraft certification and conceptual aircraft design. A comprehensive program that uses the multi-disciplinary approach for transport aircraft is presented. The model includes a geometry deck, a separate engine input deck with the main parameters, a database of engine performance from an independent simulation, and an operational deck. The comprehensive code has modules for deriving the geometry from bitmap files, an aerodynamics model for all flight conditions, a flight mechanics model for flight envelopes and mission analysis, an aircraft noise model and engine emissions. The model is validated at different levels. Validation of the aerodynamic model is done against the scale models DLR-F4 and F6. A general model analysis and flight envelope exploration are shown for the Boeing B-777-300 with GE-90 turbofan engines with intermediate passenger capacity (394 passengers in 2 classes). Validation of the flight model is done by sensitivity analysis on the wetted area (or profile drag), on the specific air range, the brake-release gross weight and the aircraft noise. A variety of results is shown, including specific air range charts, take-off weight-altitude charts, payload-range performance

Enabling alternate fuels for commercial aircraft

OpenAIRE

Daggett, D.

2010-01-01

The following reports on the past four years of work to examine the feasibility, sustainability and economic viability of developing a renewable, greenhouse-gas-neutral, liquid biofuel for commercial aircraft. The sharp increase in environmental concerns, such as global warming, as well as the volatile price fluctuations of fossil fuels, has ignited a search for alternative transportation fuels. However, commercial aircraft can not use present alternative fuels that are designed for ground...

Aircraft gas turbine engine vibration diagnostics

OpenAIRE

Stanislav Fábry; Marek Češkovič

2017-01-01

In the Czech and Slovak aviation are in service elderly aircrafts, usually produced in former Soviet Union. Their power units can be operated in more efficient way, in case of using additional diagnostic methods that allow evaluating their health. Vibration diagnostics is one of the methods indicating changes of rotational machine dynamics. Ground tests of aircraft gas turbine engines allow vibration recording and analysis. Results contribute to airworthiness evaluation and making corrections...

A Rapid Synthetic Method for the Preparation of Two Tris-Cobalt(III) Compounds.

Science.gov (United States)

Jackman, Donald C.; Rillema, D. Paul

1989-01-01

Reports a method of preparation for tris(ethylenediamine)cobalt(III) and tris(2,2'-bipyridine)cobalt(III) that will shorten the preparation time by approximately 3 hours. Notes the time for synthesis and isolation of compound one was 1 hour (yield 38 percent) while compound two took 50 minutes (yield 71%). (MVL)

Congestion Pricing for Aircraft Pushback Slot Allocation

Science.gov (United States)

Zhang, Yaping

2017-01-01

In order to optimize aircraft pushback management during rush hour, aircraft pushback slot allocation based on congestion pricing is explored while considering monetary compensation based on the quality of the surface operations. First, the concept of the “external cost of surface congestion” is proposed, and a quantitative study on the external cost is performed. Then, an aircraft pushback slot allocation model for minimizing the total surface cost is established. An improved discrete differential evolution algorithm is also designed. Finally, a simulation is performed on Xinzheng International Airport using the proposed model. By comparing the pushback slot control strategy based on congestion pricing with other strategies, the advantages of the proposed model and algorithm are highlighted. In addition to reducing delays and optimizing the delay distribution, the model and algorithm are better suited for use for actual aircraft pushback management during rush hour. Further, it is also observed they do not result in significant increases in the surface cost. These results confirm the effectiveness and suitability of the proposed model and algorithm. PMID:28114429

Congestion Pricing for Aircraft Pushback Slot Allocation.

Science.gov (United States)

Liu, Lihua; Zhang, Yaping; Liu, Lan; Xing, Zhiwei

2017-01-01

In order to optimize aircraft pushback management during rush hour, aircraft pushback slot allocation based on congestion pricing is explored while considering monetary compensation based on the quality of the surface operations. First, the concept of the "external cost of surface congestion" is proposed, and a quantitative study on the external cost is performed. Then, an aircraft pushback slot allocation model for minimizing the total surface cost is established. An improved discrete differential evolution algorithm is also designed. Finally, a simulation is performed on Xinzheng International Airport using the proposed model. By comparing the pushback slot control strategy based on congestion pricing with other strategies, the advantages of the proposed model and algorithm are highlighted. In addition to reducing delays and optimizing the delay distribution, the model and algorithm are better suited for use for actual aircraft pushback management during rush hour. Further, it is also observed they do not result in significant increases in the surface cost. These results confirm the effectiveness and suitability of the proposed model and algorithm.

Congestion Pricing for Aircraft Pushback Slot Allocation.

Directory of Open Access Journals (Sweden)

Lihua Liu

Full Text Available In order to optimize aircraft pushback management during rush hour, aircraft pushback slot allocation based on congestion pricing is explored while considering monetary compensation based on the quality of the surface operations. First, the concept of the "external cost of surface congestion" is proposed, and a quantitative study on the external cost is performed. Then, an aircraft pushback slot allocation model for minimizing the total surface cost is established. An improved discrete differential evolution algorithm is also designed. Finally, a simulation is performed on Xinzheng International Airport using the proposed model. By comparing the pushback slot control strategy based on congestion pricing with other strategies, the advantages of the proposed model and algorithm are highlighted. In addition to reducing delays and optimizing the delay distribution, the model and algorithm are better suited for use for actual aircraft pushback management during rush hour. Further, it is also observed they do not result in significant increases in the surface cost. These results confirm the effectiveness and suitability of the proposed model and algorithm.

Probabilistic assessment of NPP safety under aircraft impact

International Nuclear Information System (INIS)

Birbraer, A.N.; Roleder, A.J.; Arhipov, S.B.

1999-01-01

Methodology of probabilistic assessment of NPP safety under aircraft impact is described below. The assessment is made taking into account not only the fact of aircraft fall onto the NPP building, but another casual parameters too, namely an aircraft class, velocity and mass, as well as point and angle of its impact with the building structure. This analysis can permit to justify the decrease of the required structure strength and dynamic loads on the NPP equipment. It can also be especially useful when assessing the safety of existing NPP. (author)

Review of Idealized Aircraft Wake Vortex Models

Science.gov (United States)

Ahmad, Nashat N.; Proctor, Fred H.; Duparcmeur, Fanny M. Limon; Jacob, Don

2014-01-01

Properties of three aircraft wake vortex models, Lamb-Oseen, Burnham-Hallock, and Proctor are reviewed. These idealized models are often used to initialize the aircraft wake vortex pair in large eddy simulations and in wake encounter hazard models, as well as to define matched filters for processing lidar observations of aircraft wake vortices. Basic parameters for each vortex model, such as peak tangential velocity and circulation strength as a function of vortex core radius size, are examined. The models are also compared using different vortex characterizations, such as the vorticity magnitude. Results of Euler and large eddy simulations are presented. The application of vortex models in the postprocessing of lidar observations is discussed.

Inerting Aircraft Fuel Systems Using Exhaust Gases

Science.gov (United States)

Hehemann, David G.

2002-01-01

Our purpose in this proposal was to determine the feasibility of using carbon dioxide, possibly obtained from aircraft exhaust gases as a substance to inert the fuel contained in fuel tanks aboard aircraft. To do this, we decided to look at the effects carbon dioxide has upon commercial Jet-A aircraft fuel. In particular, we looked at the solubility of CO2 in Jet-A fuel, the pumpability of CO2-saturated Jet-A fuel, the flashpoint of Jet-A fuel under various mixtures of air and CO2, the static outgassing of CO2-Saturated Jet-A fuel and the dynamic outgassing of Jet-A fuel during pumping of Jet-A fuel.

Combined effect of rapid nitriding and plastic deformation on the surface strength, toughness and wear resistance of steel 38CrMoAlA

DEFF Research Database (Denmark)

Wang, B.; Lv, Z.A.; Zhou, Z.A.

2015-01-01

The combined treatment of pressurized gas nitriding and cold rolling is proposed as a new approach to rapid preparation of a strong and tough nitrided layer for steel 38CrMoAlA. The microstructural characteristics and properties of the modified surface layer in comparison with those of the conven......The combined treatment of pressurized gas nitriding and cold rolling is proposed as a new approach to rapid preparation of a strong and tough nitrided layer for steel 38CrMoAlA. The microstructural characteristics and properties of the modified surface layer in comparison with those...

26 x 6.6 radial-belted aircraft tire performance

Science.gov (United States)

Davis, Pamela A.; Martinson, Veloria J.; Yager, Thomas J.; Stubbs, Sandy M.

1991-01-01

Preliminary results from testing of 26 x 6.6 radial-belted and bias-ply aircraft tires at NASA Langley's Aircraft Landing Dynamics Facility (ALDF) are reviewed. The 26 x 6.6 tire size evaluation includes cornering performance tests throughout the aircraft ground operational speed range for both dry and wet runway surfaces. Static test results to define 26 x 6.6 tire vertical stiffness properties are also presented and discussed.

Copycats in Pilot Aircraft-Assisted Suicides after the Germanwings Incident

Directory of Open Access Journals (Sweden)

Tanja Laukkala

2018-03-01

Full Text Available Aircraft-assisted pilot suicide is a rare but serious phenomenon. The aim of this study was to evaluate changes in pilot aircraft-assisted suicide risks, i.e., a copycat effect, in the U.S. and Germany after the Germanwings 2015 incident in the French Alps. Aircraft-assisted pilot suicides were searched in the U.S. National Transportation Safety Board (NTSB accident investigation database and in the German Bundestelle für Flugunfalluntersuchung (BFU Reports of Investigation database five years before and two years after the deliberate crash of the Germanwings flight into the French Alps in 2015. The relative risk (RR of the aircraft-assisted pilot suicides was calculated. Two years after the incident, three out of 454 (0.66% fatal incidents were aircraft-assisted suicides compared with six out of 1292 (0.46% in the prior five years in the NTSB database. There were no aircraft-assisted pilot suicides in the German database during the two years after or five years prior to the Germanwings crash. The relative aircraft-assisted pilot suicide risk for the U.S. was 1.4 (95% CI 0.3–4.2 which was not statistically significant. Six of the pilots who died by suicide had told someone of their suicidal intentions. We consider changes in the rate to be within a normal variation. Responsible media coverage of aircraft incidents is important due to the large amount of publicity that these events attract.

Copycats in Pilot Aircraft-Assisted Suicides after the Germanwings Incident

Science.gov (United States)

Vuorio, Alpo; Bor, Robert; Budowle, Bruce; Navathe, Pooshan; Pukkala, Eero; Sajantila, Antti

2018-01-01

Aircraft-assisted pilot suicide is a rare but serious phenomenon. The aim of this study was to evaluate changes in pilot aircraft-assisted suicide risks, i.e., a copycat effect, in the U.S. and Germany after the Germanwings 2015 incident in the French Alps. Aircraft-assisted pilot suicides were searched in the U.S. National Transportation Safety Board (NTSB) accident investigation database and in the German Bundestelle für Flugunfalluntersuchung (BFU) Reports of Investigation database five years before and two years after the deliberate crash of the Germanwings flight into the French Alps in 2015. The relative risk (RR) of the aircraft-assisted pilot suicides was calculated. Two years after the incident, three out of 454 (0.66%) fatal incidents were aircraft-assisted suicides compared with six out of 1292 (0.46%) in the prior five years in the NTSB database. There were no aircraft-assisted pilot suicides in the German database during the two years after or five years prior to the Germanwings crash. The relative aircraft-assisted pilot suicide risk for the U.S. was 1.4 (95% CI 0.3–4.2) which was not statistically significant. Six of the pilots who died by suicide had told someone of their suicidal intentions. We consider changes in the rate to be within a normal variation. Responsible media coverage of aircraft incidents is important due to the large amount of publicity that these events attract. PMID:29534475

The effect of excitation and preparation pulses on nonslice selective 2D UTE bicomponent analysis of bound and free water in cortical bone at 3T

Energy Technology Data Exchange (ETDEWEB)

Li, Shihong [Department of Radiology, University of California, San Diego, California 92103-8226 (United States); Department of Radiology, Hua Dong Hospital, Fudan University, Shanghai 200040 (China); Yancheng Medical College, Jiangsu (China); The First People' s Hospital of Yancheng City, Jiangsu 224005 (China); Chang, Eric Y.; Chung, Christine B. [VA San Diego Healthcare System, San Diego, California 92161 and Department of Radiology, University of California, San Diego, California 92103-8226 (United States); Bae, Won C.; Du, Jiang, E-mail: jiangdu@ucsd.edu [Department of Radiology, University of California, San Diego, California 92103-8226 (United States); Hua, Yanqing [Department of Radiology, Hua Dong Hospital, Fudan University, Shanghai 200040 (China); Zhou, Yi [The First People' s Hospital of Yancheng City, Jiangsu 224005 (China)

2014-02-15

Purpose: The purpose of this study was to investigate the effect of excitation, fat saturation, long T2 saturation, and adiabatic inversion pulses on ultrashort echo time (UTE) imaging with bicomponent analysis of bound and free water in cortical bone for potential applications in osteoporosis. Methods: Six bovine cortical bones and six human tibial midshaft samples were harvested for this study. Each bone sample was imaged with eight sequences using 2D UTE imaging at 3T with half and hard excitation pulses, without and with fat saturation, long T2 saturation, and adiabatic inversion recovery (IR) preparation pulses. Single- and bicomponent signal models were utilized to calculate the T2{sup *}s and/or relative fractions of short and long T2{sup *}s. Results: For all bone samples UTE T2{sup *} signal decay showed bicomponent behavior. A higher short T2{sup *} fraction was observed on UTE images with hard pulse excitation compared with half pulse excitation (75.6% vs 68.8% in bovine bone, 79.9% vs 73.2% in human bone). Fat saturation pulses slightly reduced the short T2{sup *} fraction relative to regular UTE sequences (5.0% and 2.0% reduction, respectively, with half and hard excitation pulses for bovine bone, 6.3% and 8.2% reduction, respectively, with half and hard excitation pulses for human bone). Long T2 saturation pulses significantly reduced the long T2{sup *} fraction relative to regular UTE sequence (18.9% and 17.2% reduction, respectively, with half and hard excitation pulses for bovine bone, 26.4% and 27.7% reduction, respectively, with half and hard excitation pulses for human bone). With IR-UTE preparation the long T2{sup *} components were significantly reduced relative to regular UTE sequence (75.3% and 66.4% reduction, respectively, with half and hard excitation pulses for bovine bone, 87.7% and 90.3% reduction, respectively, with half and hard excitation pulses for human bone). Conclusions: Bound and free water T2{sup *}s and relative fractions can

The effect of excitation and preparation pulses on nonslice selective 2D UTE bicomponent analysis of bound and free water in cortical bone at 3T

International Nuclear Information System (INIS)

Li, Shihong; Chang, Eric Y.; Chung, Christine B.; Bae, Won C.; Du, Jiang; Hua, Yanqing; Zhou, Yi

2014-01-01

Purpose: The purpose of this study was to investigate the effect of excitation, fat saturation, long T2 saturation, and adiabatic inversion pulses on ultrashort echo time (UTE) imaging with bicomponent analysis of bound and free water in cortical bone for potential applications in osteoporosis. Methods: Six bovine cortical bones and six human tibial midshaft samples were harvested for this study. Each bone sample was imaged with eight sequences using 2D UTE imaging at 3T with half and hard excitation pulses, without and with fat saturation, long T2 saturation, and adiabatic inversion recovery (IR) preparation pulses. Single- and bicomponent signal models were utilized to calculate the T2 * s and/or relative fractions of short and long T2 * s. Results: For all bone samples UTE T2 * signal decay showed bicomponent behavior. A higher short T2 * fraction was observed on UTE images with hard pulse excitation compared with half pulse excitation (75.6% vs 68.8% in bovine bone, 79.9% vs 73.2% in human bone). Fat saturation pulses slightly reduced the short T2 * fraction relative to regular UTE sequences (5.0% and 2.0% reduction, respectively, with half and hard excitation pulses for bovine bone, 6.3% and 8.2% reduction, respectively, with half and hard excitation pulses for human bone). Long T2 saturation pulses significantly reduced the long T2 * fraction relative to regular UTE sequence (18.9% and 17.2% reduction, respectively, with half and hard excitation pulses for bovine bone, 26.4% and 27.7% reduction, respectively, with half and hard excitation pulses for human bone). With IR-UTE preparation the long T2 * components were significantly reduced relative to regular UTE sequence (75.3% and 66.4% reduction, respectively, with half and hard excitation pulses for bovine bone, 87.7% and 90.3% reduction, respectively, with half and hard excitation pulses for human bone). Conclusions: Bound and free water T2 * s and relative fractions can be assessed using UTE bicomponent

Heterocyclic aromatic amines in domestically prepared chicken and fish from Singapore Chinese households.

Science.gov (United States)

Salmon, C P; Knize, M G; Felton, J S; Zhao, B; Seow, A

2006-04-01

Chicken and fish samples prepared by 42 Singapore Chinese in their homes were obtained. Researchers were present to collect data on raw sample weight, cooking time, maximum cooking surface temperature, and cooked sample weight. Each participant prepared one pan-fried fish sample and two pan-fried chicken samples, one marinated, one not marinated. The cooked samples were analyzed for five heterocyclic aromatic amine (HAA) mutagens, including MeIQx (2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline); 4,8-DiMeIQx (2-amino-3,4,8-trimethylimidazo[4,5-f]quinoxaline); 7,8-DiMeIQx (2-amino-3,7,8-trimethylimidazo[4,5-f]quinoxaline); PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine), and IFP (2-amino-(1,6-dimethylfuro[3,2-e]imidazo[4,5-b])pyridine). A paired Student's t-test showed that marinated chicken had lower concentrations of PhIP (pchicken, and also that weight loss due to cooking was less in marinated chicken than in non-marinated chicken (pchicken (pchicken (pchicken (pchicken (pchicken (p<0.05). This study provides new information on HAA content in the Singapore Chinese diet.

Aircraft family design using enhanced collaborative optimization

Science.gov (United States)

Roth, Brian Douglas

Significant progress has been made toward the development of multidisciplinary design optimization (MDO) methods that are well-suited to practical large-scale design problems. However, opportunities exist for further progress. This thesis describes the development of enhanced collaborative optimization (ECO), a new decomposition-based MDO method. To support the development effort, the thesis offers a detailed comparison of two existing MDO methods: collaborative optimization (CO) and analytical target cascading (ATC). This aids in clarifying their function and capabilities, and it provides inspiration for the development of ECO. The ECO method offers several significant contributions. First, it enhances communication between disciplinary design teams while retaining the low-order coupling between them. Second, it provides disciplinary design teams with more authority over the design process. Third, it resolves several troubling computational inefficiencies that are associated with CO. As a result, ECO provides significant computational savings (relative to CO) for the test cases and practical design problems described in this thesis. New aircraft development projects seldom focus on a single set of mission requirements. Rather, a family of aircraft is designed, with each family member tailored to a different set of requirements. This thesis illustrates the application of decomposition-based MDO methods to aircraft family design. This represents a new application area, since MDO methods have traditionally been applied to multidisciplinary problems. ECO offers aircraft family design the same benefits that it affords to multidisciplinary design problems. Namely, it simplifies analysis integration, it provides a means to manage problem complexity, and it enables concurrent design of all family members. In support of aircraft family design, this thesis introduces a new wing structural model with sufficient fidelity to capture the tradeoffs associated with component

Analysis of Automated Aircraft Conflict Resolution and Weather Avoidance

Science.gov (United States)

Love, John F.; Chan, William N.; Lee, Chu Han

2009-01-01

This paper describes an analysis of using trajectory-based automation to resolve both aircraft and weather constraints for near-term air traffic management decision making. The auto resolution algorithm developed and tested at NASA-Ames to resolve aircraft to aircraft conflicts has been modified to mitigate convective weather constraints. Modifications include adding information about the size of a gap between weather constraints to the routing solution. Routes that traverse gaps that are smaller than a specific size are not used. An evaluation of the performance of the modified autoresolver to resolve both conflicts with aircraft and weather was performed. Integration with the Center-TRACON Traffic Management System was completed to evaluate the effect of weather routing on schedule delays.

Parameterized Flight Mission for Secondary Power Requirement Estimations of Commercial Transport Aircraft

OpenAIRE

Lampl, Thomas; Muschkorgel, Sandra; Hornung, Mirko;

2018-01-01

The trend towards More-Electric Aircraft (MEA) and the introduction of new system technologies lead to considerable changes at the system level of commercial transport aircraft. Because the number of systems and power requirements are increasing, the consideration and integration of aircraft systems in early aircraft design phases is important. The objective of this contribution is to develop a characteristic flight mission with modelled aircraft systems to estimate the secondary power requir...

Aircraft parameter estimation

Indian Academy of Sciences (India)

With the evolution of high performance modern aircraft and spiraling developmental and experimental costs, the importance of flight validated databases for flight control design applications and for flight simulators has increased significantly in the recent past. Ground-based and in-flight simulators are increasingly used not ...

Corrosion Sensor Development for Condition-Based Maintenance of Aircraft

Directory of Open Access Journals (Sweden)

Gino Rinaldi

2012-01-01

Full Text Available Aircraft routinely operate in atmospheric environments that, over time, will impact their structural integrity. Material protection and selection schemes notwithstanding, recurrent exposure to chlorides, pollution, temperature gradients, and moisture provide the necessary electrochemical conditions for the development and profusion of corrosion in aircraft structures. For aircraft operators, this becomes an important safety matter as corrosion found in a given aircraft must be assumed to be present in all of that type of aircraft. This safety protocol and its associated unscheduled maintenance requirement drive up the operational costs of the fleet and limit the availability of the aircraft. Hence, there is an opportunity at present for developing novel sensing technologies and schemes to aid in shifting time-based maintenance schedules towards condition-based maintenance procedures. In this work, part of the ongoing development of a multiparameter integrated corrosion sensor is presented. It consists of carbon nanotube/polyaniline polymer sensors and commercial-off-the-shelf sensors. It is being developed primarily for monitoring environmental and material factors for the purpose of providing a means to more accurately assess the structural integrity of aerospace aluminium alloys through fusion of multiparameter sensor data. Preliminary experimental test results are presented for chloride ion concentration, hydrogen gas evolution, humidity variations, and material degradation.

Improving aircraft accident forecasting for an integrated plutonium storage facility

International Nuclear Information System (INIS)

Rock, J.C.; Kiffe, J.; McNerney, M.T.; Turen, T.A.

1998-06-01

Aircraft accidents pose a quantifiable threat to facilities used to store and process surplus weapon-grade plutonium. The Department of Energy (DOE) recently published its first aircraft accident analysis guidelines: Accident Analysis for Aircraft Crash into Hazardous Facilities. This document establishes a hierarchy of procedures for estimating the small annual frequency for aircraft accidents that impact Pantex facilities and the even smaller frequency of hazardous material released to the environment. The standard establishes a screening threshold of 10 -6 impacts per year; if the initial estimate of impact frequency for a facility is below this level, no further analysis is required. The Pantex Site-Wide Environmental Impact Statement (SWEIS) calculates the aircraft impact frequency to be above this screening level. The DOE Standard encourages more detailed analyses in such cases. This report presents three refinements, namely, removing retired small military aircraft from the accident rate database, correcting the conversion factor from military accident rates (accidents per 100,000 hours) to the rates used in the DOE model (accidents per flight phase), and adjusting the conditional probability of impact for general aviation to more accurately reflect pilot training and local conditions. This report documents a halving of the predicted frequency of an aircraft impact at Pantex and points toward further reductions

49 CFR 173.172 - Aircraft hydraulic power unit fuel tank.

Science.gov (United States)

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Aircraft hydraulic power unit fuel tank. 173.172... Class 1 and Class 7 § 173.172 Aircraft hydraulic power unit fuel tank. Aircraft hydraulic power unit fuel tanks containing a mixture of anhydrous hydrazine and monomethyl hydrazine (M86 fuel) and designed...

CALCULATION OF CATALYTIC REACTIVITY FOR PREPARING DICHLORODIMETHYLSILANE UTILIZING PRE- AND POST-MODIFIED 24T AlCl3/ZSM-5

Directory of Open Access Journals (Sweden)

Wenyuan Xu

Full Text Available Dichlorodimethylsilane is the most important raw material for the preparation of organic silicon materials. Currently, the preparation of dichlorodimethylsilane is mainly based on disproportionation method. This method can turn wastes (by-products into treasures but the mechanism is still indeterminate. In this study, MP2/6-311++G (3df, 2pd basis set was used to study the mechanism of the disproportionation for producing dichlorodimethylsilane. Dichlorodimethylsilane is catalyzed by 24T cluster AlCl3/ZSM-5 catalyst and modified by (AlCl2+, and (BCl2+. The calculation results show that the rate-determining step is the reaction of the catalyst with trimethylchlorosilane . The activation energy of the rate-determining step of main reaction is: 393.83, 427.73, and 527.61 kJ mol-1, respectively. The structure analysis, activation energy analysis and LOL analysis for different catalysts all show that the catalytic effect of unmodified AlCl3/ZSM-5 is better.

Preparation of rT3 in human serum ria kit

International Nuclear Information System (INIS)

Zhang Peixuan; Han Shiquan; Zhang Liling

1991-02-01

A method for the measurement of rT 3 in serum by radioimmunoassay is presented. The double antibody plus polyethylene glycol was used as separating reagent. The method is simple, precise and sensitive. Serum rT 3 values of normal (n = 61) were 47.7 ± 11.34 x 10 -8 g/L (X-bar ± SD). Patients with hyperthyroidism (n = 8) serum rT 3 values were 272.2 ± 91.1 x 10 -8 g/L (X-bar ± SD) and patients with hypothyroidism (n = 2) serum rT 3 values were 11.4 ± 8.3 x 10 -8 g/L (X-bar ± SD). It appears to be a useful diagnostic procedure for thyroid diseases

Optimised Sound Absorbing Trim Panels for the Reduction of Aircraft Cabin Noise

NARCIS (Netherlands)

Hannink, M.H.C.; Wijnant, Ysbrand H.; de Boer, Andries; Ivanov, N.I.; Crocker, M.J.

2004-01-01

The EU project FACE (Friendly Aircraft Cabin Environment) aims to improve the environmental comfort in aircraft cabins. As part of this project, this paper focuses on the reduction of noise in aircraft cabins. For modern aircraft flying at cruise conditions, this cabin noise is known to be dominated

Fiscal 1999 research report on long-term energy technology strategy. Basic research on industrial technology strategy (Individual technology strategy). Aerospace technology field (Aircraft technology field); 1999 nendo choki energy gijutsu senryaku nado ni kansuru chosa hokokusho. Sangyo gijutsu senryaku sakutei kiban chosa (bun'yabetsu gijutsu senryaku (kokuki gijutsu bun'ya))

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-03-01

This report summarizes the fiscal 1999 basic research result on industrial technology strategy of an aircraft technology field. In an aircraft field, since the major theme is application of new technologies to new airframe development, with joining in international cooperative development of aircraft, Japanese initiative development of airframes based on the domestic market demands and profitability should be started as early as possible. Because there is no airframe development by only one country including U.S.A., Japan is profitable to unite with some overseas companies, and invest selectively in specific leading fields. Positive technical support to safety, reliability, comfort and environment harmony are also important. More important theme than establishment of elementary technologies is preparation of an integrated flight demonstration system to expand application chances of development results, and preparation of various test facilities for tests required during development activities. Application of information technologies to the whole aircraft industry, and organic cooperation between the private and public sectors are also important. (NEDO)

Comparative Analysis of Conventional Electronic and OZ Concept Displays for Aircraft Energy Management

Science.gov (United States)

Baker, Erik Reese

A repeated-measures, within-subjects design was conducted on 58 participant pilots to assess mean differences on energy management situation awareness response time and response accuracy between a conventional electronic aircraft display, a primary flight display (PFD), and an ecological interface design aircraft display, the OZ concept display. Participants were associated with a small Midwestern aviation university, including student pilots, flight instructors, and faculty with piloting experience. Testing consisted of observing 15 static screenshots of each cockpit display type and then selecting applicable responses from 27 standardized responses for each screen. A paired samples t-test was computed comparing accuracy and response time for the two displays. There was no significant difference in means between PFD Response Time and OZ Response Time. On average, mean PFD Accuracy was significantly higher than mean OZ Accuracy (MDiff = 13.17, SDDiff = 20.96), t(57) = 4.78, p performance differences were not operationally remarkable. There was no significant correlation between PFD Response Time and PFD Accuracy, but there was a significant correlation between OZ Response Time and OZ Accuracy, r (58) = .353, p performing as well as experienced professional pilots on dynamic flight tasks with the OZ display. A demographic questionnaire and a feedback survey were included in the trial. An equivalent three-quarters majority of participants rated the PFD as "easy" and the OZ as "confusing", yet performance accuracy and response times between the two displays were not operationally different.

Deep surface rolling for fatigue life enhancement of laser clad aircraft aluminium alloy

Energy Technology Data Exchange (ETDEWEB)

Zhuang, W., E-mail: wyman.zhuang@dsto.defence.gov.au [Aerospace Division, Defence Science and Technology Organisation, 506 Lorimer Street, Fishermans Bend, Victoria 3207 (Australia); Liu, Q.; Djugum, R.; Sharp, P.K. [Aerospace Division, Defence Science and Technology Organisation, 506 Lorimer Street, Fishermans Bend, Victoria 3207 (Australia); Paradowska, A. [Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW 2232 (Australia)

2014-11-30

Highlights: • Deep surface rolling as a post-repair enhancement technology was applied to the laser cladded 7075-T651 aluminium alloy specimens that simulated corrosion damage blend-out repair. • The residual stresses induced by the deep surface rolling process were measured. • The deep surface rolling process can introduce deep and high magnitude compressive residual stresses beyond the laser clad and substrate interface. • Spectrum fatigue test showed the fatigue life was significantly increased by deep surface rolling. - Abstract: Deep surface rolling can introduce deep compressive residual stresses into the surface of aircraft metallic structure to extend its fatigue life. To develop cost-effective aircraft structural repair technologies such as laser cladding, deep surface rolling was considered as an advanced post-repair surface enhancement technology. In this study, aluminium alloy 7075-T651 specimens with a blend-out region were first repaired using laser cladding technology. The surface of the laser cladding region was then treated by deep surface rolling. Fatigue testing was subsequently conducted for the laser clad, deep surface rolled and post-heat treated laser clad specimens. It was found that deep surface rolling can significantly improve the fatigue life in comparison with the laser clad baseline repair. In addition, three dimensional residual stresses were measured using neutron diffraction techniques. The results demonstrate that beneficial compressive residual stresses induced by deep surface rolling can reach considerable depths (more than 1.0 mm) below the laser clad surface.

Deep surface rolling for fatigue life enhancement of laser clad aircraft aluminium alloy

International Nuclear Information System (INIS)

Zhuang, W.; Liu, Q.; Djugum, R.; Sharp, P.K.; Paradowska, A.

2014-01-01

Highlights: • Deep surface rolling as a post-repair enhancement technology was applied to the laser cladded 7075-T651 aluminium alloy specimens that simulated corrosion damage blend-out repair. • The residual stresses induced by the deep surface rolling process were measured. • The deep surface rolling process can introduce deep and high magnitude compressive residual stresses beyond the laser clad and substrate interface. • Spectrum fatigue test showed the fatigue life was significantly increased by deep surface rolling. - Abstract: Deep surface rolling can introduce deep compressive residual stresses into the surface of aircraft metallic structure to extend its fatigue life. To develop cost-effective aircraft structural repair technologies such as laser cladding, deep surface rolling was considered as an advanced post-repair surface enhancement technology. In this study, aluminium alloy 7075-T651 specimens with a blend-out region were first repaired using laser cladding technology. The surface of the laser cladding region was then treated by deep surface rolling. Fatigue testing was subsequently conducted for the laser clad, deep surface rolled and post-heat treated laser clad specimens. It was found that deep surface rolling can significantly improve the fatigue life in comparison with the laser clad baseline repair. In addition, three dimensional residual stresses were measured using neutron diffraction techniques. The results demonstrate that beneficial compressive residual stresses induced by deep surface rolling can reach considerable depths (more than 1.0 mm) below the laser clad surface

Cosmic radiation and airline pilots: Exposure pattern as a function of aircraft type

Energy Technology Data Exchange (ETDEWEB)

Tveten, U.; Haldorsen, T.; Reitan, J

2000-07-01

The project presented here has been carried out as part of an epidemiological project on Norwegian aircraft personnel, entitled 'Exposure to low level ionising radiation and incidence of cancer in airline pilots and crew'. The purpose of the main project is to determine if there may be a relationship between exposure to cosmic radiation at aircraft cruising altitudes and the incidence of cancer. The methodology used as basis for estimating the radiation exposures is presented. The information used as basis for the dose estimations comes from a variety of sources: the files at the Personnel Licensing Section and the Aviation Medical Section of Norwegian Aviation Administration, the route tables of Scandinavian Airlines System (SAS), large amounts of expert information contributed by members of the Pilot's Associations in Norway and a couple of non-Norwegian pilots and from other members of the staff of SAS and other airlines. The estimation for each pilot was based on individual information of annual block hours and an estimated doserate for each type of aircraft. The latter was estimated as a weighted average of CARI-estimated doses on a selection of routes flown by the airplanes in the different time periods. The project includes all pilots that have been licensed in Norway since 1946. These pilots have been flying a large variety of different types of aircraft and routes. The cosmic radiation intensity is a function of altitude in the atmosphere and, less markedly, of geographical latitude and of the intensity of the radiation from the sun (quantified as the heliocentric potential). Different types of aircraft fly at different altitudes and are used for different purposes (passenger traffic, cargo, air photography, preparation of maps etc) and used on different routes. The end results of the project described in this article are radiation exposures per block hour for each type of aircraft, and for each individual year (the differences between years

Molecular Cloning and Characterization of a P38-Like Mitogen-Activated Protein Kinase from Echinococcus granulosus.

Science.gov (United States)

Lü, Guodong; Li, Jing; Zhang, Chuanshan; Li, Liang; Bi, Xiaojuan; Li, Chaowang; Fan, Jinliang; Lu, Xiaomei; Vuitton, Dominique A; Wen, Hao; Lin, Renyong

2016-12-01

Cystic echinococcosis (CE) treatment urgently requires a novel drug. The p38 mitogen-activated protein kinases (MAPKs) are a family of Ser/Thr protein kinases, but still have to be characterized in Echinococcus granulosus . We identified a 1,107 bp cDNA encoding a 368 amino acid MAPK protein (Egp38) in E. granulosus . Egp38 exhibits 2 distinguishing features of p38-like kinases: a highly conserved T-X-Y motif and an activation loop segment. Structural homology modeling indicated a conserved structure among Egp38, EmMPK2, and H. sapiens p38α, implying a common binding mechanism for the ligand domain and downstream signal transduction processing similar to that described for p38α. Egp38 and its phosphorylated form are expressed in the E. granulosus larval stages vesicle and protoscolices during intermediate host infection of an intermediate host. Treatment of in vitro cultivated protoscolices with the p38-MAPK inhibitor ML3403 effectively suppressed Egp38 activity and led to significant protoscolices death within 5 days. Treatment of in vitro-cultivated protoscolices with TGF-β1 effectively induced Egp38 phosphorylation. In summary, the MAPK, Egp38, was identified in E. granulosus , as an anti-CE drug target and participates in the interplay between the host and E. granulosus via human TGF-β1.

Wide Body Aircraft Demand Potential at Washington National Airport,

Science.gov (United States)

1977-09-01

the city-pair markets. Probably the most important feature of FA-7 is the fact that it allows for investigation of the behavior of airlines to changes...FINANCIAL INFORMfATION YLIGHTS BY AIRCRAFT TPE ~.4/J \\ FUEL COSUMED PASSENGERS UARRIED BY TOA IR F FLIGHITS TOTAL AIRCRAFT USAGE coded data. Sample...the various levels of operations. Similar behavior can be identified in the simultaneous increase of both types of aircraft at Dulles. Tables lAthrough