Final Technical Progress Report: Development of Low-Cost Suspension Heliostat; December 7, 2011 - December 6, 2012

Energy Technology Data Exchange (ETDEWEB)

Bender, W.

2013-01-01

Final technical progress report of SunShot Incubator Solaflect Energy. The project succeeded in demonstrating that the Solaflect Suspension Heliostat design is viable for large-scale CSP installations. Canting accuracy is acceptable and is continually improving as Solaflect improves its understanding of this design. Cost reduction initiatives were successful, and there are still many opportunities for further development and further cost reduction.

Nuclear research with the electromagnetic probe. Final progress report

Energy Technology Data Exchange (ETDEWEB)

Meziani, Z.E.

1994-10-01

This is the final report on the research carried at Stanford University under contract DE-FG03-88ER40439. All the work accomplished under this grant is reported in the publications listed as part of the Principal Investigator bibliography at the end of this report. In the last few years our research was directed at some of the forefront questions in nuclear physics. We investigated the nuclear medium effects on the intrinsic properties of bound nucleons, specifically the ectromagnetic form factors. For these studies we performed a number of specialized electron scattering experiments with specific sensitivity to nuclear medium effects. At the next level of structure, elementary constituents of matter are quarks and gluons. Defining the energy regime where the quark-gluon description of nuclear systems becomes more relevant than the nucleon-meson description is of great importance in thoroughly understanding the nuclear structure. To explore this transition region, we studied the scaling region in the disintegration of the deuteron, the simplest nuclear system with high energy photons. Finally we focused on the investigation of the nucleon internal spin structure along with the test of the Bjoerken sum rule a fundamental sum rule of QCD.

Nuclear research with the electromagnetic probe. Final progress report

International Nuclear Information System (INIS)

Meziani, Z.E.

1994-10-01

This is the final report on the research carried at Stanford University under contract DE-FG03-88ER40439. All the work accomplished under this grant is reported in the publications listed as part of the Principal Investigator bibliography at the end of this report. In the last few years our research was directed at some of the forefront questions in nuclear physics. We investigated the nuclear medium effects on the intrinsic properties of bound nucleons, specifically the ectromagnetic form factors. For these studies we performed a number of specialized electron scattering experiments with specific sensitivity to nuclear medium effects. At the next level of structure, elementary constituents of matter are quarks and gluons. Defining the energy regime where the quark-gluon description of nuclear systems becomes more relevant than the nucleon-meson description is of great importance in thoroughly understanding the nuclear structure. To explore this transition region, we studied the scaling region in the disintegration of the deuteron, the simplest nuclear system with high energy photons. Finally we focused on the investigation of the nucleon internal spin structure along with the test of the Bjoerken sum rule a fundamental sum rule of QCD

Progress on the SNS target station

International Nuclear Information System (INIS)

Carne, A.

1983-01-01

This review gives progress and modifications covering the last eighteen months, under the five broad areas of target, target assembly, control system, bulk shield and remote handling. Finally a discussion of additional facilities to the SNS is presented

Progress in Development of the ITER Plasma Control System Simulation Platform

Science.gov (United States)

Walker, Michael; Humphreys, David; Sammuli, Brian; Ambrosino, Giuseppe; de Tommasi, Gianmaria; Mattei, Massimiliano; Raupp, Gerhard; Treutterer, Wolfgang; Winter, Axel

2017-10-01

We report on progress made and expected uses of the Plasma Control System Simulation Platform (PCSSP), the primary test environment for development of the ITER Plasma Control System (PCS). PCSSP will be used for verification and validation of the ITER PCS Final Design for First Plasma, to be completed in 2020. We discuss the objectives of PCSSP, its overall structure, selected features, application to existing devices, and expected evolution over the lifetime of the ITER PCS. We describe an archiving solution for simulation results, methods for incorporating physics models of the plasma and physical plant (tokamak, actuator, and diagnostic systems) into PCSSP, and defining characteristics of models suitable for a plasma control development environment such as PCSSP. Applications of PCSSP simulation models including resistive plasma equilibrium evolution are demonstrated. PCSSP development supported by ITER Organization under ITER/CTS/6000000037. Resistive evolution code developed under General Atomics' Internal funding. The views and opinions expressed herein do not necessarily reflect those of the ITER Organization.

Final focus systems for linear colliders

International Nuclear Information System (INIS)

Helm, R.; Irwin, J.

1992-08-01

Final focus systems for linear colliders present many exacting challenges in beam optics, component design, and beam quality. Efforts to resolve these problems as they relate to a new generation of linear colliders are under way at several laboratories around the world. We will outline criteria for final focus systems and discuss the current state of understanding and resolution of the outstanding problems. We will discuss tolerances on alignment, field quality and stability for optical elements, and the implications for beam parameters such as emittance, energy spread, bunch length, and stability in position and energy. Beam-based correction procedures, which in principle can alleviate many of the tolerances, will be described. Preliminary results from the Final Focus Test Beam (FFTB) under construction at SLAC will be given. Finally, we mention conclusions from operating experience at the Stanford Linear Collider (SLC)

Final focus systems for linear colliders

International Nuclear Information System (INIS)

Helm, R.; Irwing, J.

1992-01-01

Final focus systems for linear colliders present many exacting challenges in beam optics, component design, and beam quality. Efforts to resolve these problems as they relate to a new generation of linear colliders are under way at several laboratories around the world. We outline criteria for final focus systems and discuss the current state of understanding and resolution of the outstanding problems. We discuss tolerances on alignment, field quality and stability for optical elements, and the implications for beam parameters such as emittance, energy spread , bunch length, and stability in position and energy. Beam-based correction procedures, which in principle can alleviate many of the tolerances, are described. Preliminary results from the Final Focus Test Beam (FFTB) under construction at SLAC are given. Finally, we mention conclusions from operating experience at the Stanford Linear Collider (SLC). (Author) 16 refs., 4 tabs., 6 figs

ORGANIZATION OF PROGRESS AND ATTENDANCE TRACKING IN THE MOODLE LEARNING MANAGEMENT SYSTEM

Directory of Open Access Journals (Sweden)

A. Scherbyna

2014-04-01

Full Text Available The article considers usage of Moodle learning management system for current progress and attendance tracking of full time students. Evaluation systems, which are used in universities of Ukraine, are analyzed. Their basis in most cases is point accumulation system, which is useful for manual calculation of final grades at the end of the semester, but it is not useful for comparison of current students’ achievements at different subjects or achievements at any time during the semester. Also this system is not useful for putting current grades, because teaches often have to use unusual grade scales which are different from 5-point system. Because of that it is proposed to use mathematically equivalent weighted average grade, which allows to avoid mentioned disadvantages. Questions of implementation of proposed system are considered by means of gradebook of Moodle learning management system. Attendance accounting module is considered and method of using subcourse module for attendance and grades shared data import in course gradebook, where student’s rating is calculated for all disciplines is proposed.

[Geothermal system temperature-depth database and model for data analysis]. 5. quarterly technical progress report

Energy Technology Data Exchange (ETDEWEB)

Blackwell, D.D.

1998-04-25

During this first quarter of the second year of the contract activity has involved several different tasks. The author has continued to work on three tasks most intensively during this quarter: the task of implementing the data base for geothermal system temperature-depth, the maintenance of the WWW site with the heat flow and gradient data base, and finally the development of a modeling capability for analysis of the geothermal system exploration data. The author has completed the task of developing a data base template for geothermal system temperature-depth data that can be used in conjunction with the regional data base that he had already developed and is now implementing it. Progress is described.

Early detection of emphysema progression

DEFF Research Database (Denmark)

Gorbunova, Vladlena; Jacobs, Sander S A M; Lo, Pechin

2010-01-01

Emphysema is one of the most widespread diseases in subjects with smoking history. The gold standard method for estimating the severity of emphysema is a lung function test, such as forced expiratory volume in first second (FEV1). However, several clinical studies showed that chest CT scans offer...... more sensitive estimates of emphysema progression. The standard CT densitometric score of emphysema is the relative area of voxels below a threshold (RA). The RA score is a global measurement and reflects the overall emphysema progression. In this work, we propose a framework for estimation of local...... emphysema progression from longitudinal chest CT scans. First, images are registered to a common system of coordinates and then local image dissimilarities are computed in corresponding anatomical locations. Finally, the obtained dissimilarity representation is converted into a single emphysema progression...

Progress in the ITER electron cyclotron heating and current drive system design

Energy Technology Data Exchange (ETDEWEB)

Omori, Toshimichi, E-mail: toshimichi.omori@iter.org [ITER Organization, Route de Vinon sur Verdon, CS 90 046, 13067 St Paul Lez Durance Cedex (France); Albajar, Ferran; Bonicelli, Tullio; Carannante, Giuseppe; Cavinato, Mario; Cismondi, Fabio [Fusion for Energy, Josep Pla 2, Barcelona 08019 (Spain); Darbos, Caroline [ITER Organization, Route de Vinon sur Verdon, CS 90 046, 13067 St Paul Lez Durance Cedex (France); Denisov, Grigory [Institute of Applied Physics Russian Academy of Sciences, 46 Ulyanov Street, Nizhny Novgorod 603950 (Russian Federation); Farina, Daniela [Istituto di Fisica del Plasma, Association EURATOM-ENEA-CNR, Milano (Italy); Gagliardi, Mario [Fusion for Energy, Josep Pla 2, Barcelona 08019 (Spain); Gandini, Franco; Gassmann, Thibault [ITER Organization, Route de Vinon sur Verdon, CS 90 046, 13067 St Paul Lez Durance Cedex (France); Goodman, Timothy [CRPP, Association EURATOM-Confédération Suisse, EPFL Ecublens, CH-1015 Lausanne (Switzerland); Hanson, Gregory [US ITER Project Office, ORNL, 055 Commerce Park, PO Box 2008, Oak Ridge, TN 37831 (United States); Henderson, Mark A. [ITER Organization, Route de Vinon sur Verdon, CS 90 046, 13067 St Paul Lez Durance Cedex (France); Kajiwara, Ken [Japan Atomic Energy Agency (JAEA), 801-1 Mukoyama, Naka-shi, Ibaraki 311-0193 (Japan); McElhaney, Karen [US ITER Project Office, ORNL, 055 Commerce Park, PO Box 2008, Oak Ridge, TN 37831 (United States); Nousiainen, Risto [Fusion for Energy, Josep Pla 2, Barcelona 08019 (Spain); Oda, Yasuhisa [Japan Atomic Energy Agency (JAEA), 801-1 Mukoyama, Naka-shi, Ibaraki 311-0193 (Japan); Oustinov, Alexander [Institute of Applied Physics Russian Academy of Sciences, 46 Ulyanov Street, Nizhny Novgorod 603950 (Russian Federation); and others

2015-10-15

Highlights: • EC system is designed with an ability to upgrade in power to 28 MW then 40 MW. • The TL is capable of 3 buildings movements; ±15 mm displacements at the worst. • Improved power deposition access injecting 20 MW across nearly the entire plasma. • Ensured nuclear safety by appropriate definition of confinement boundaries. • Proposed I&C architecture for the overall EC plant was successfully reviewed. - Abstract: An electron cyclotron system is one of the four auxiliary plasma heating systems to be installed on the ITER tokamak. The ITER EC system consists of 24 gyrotrons with associated 12 high voltage power supplies, a set of evacuated transmission lines and two types of launchers. The whole system is designed to inject 20 MW of microwave power at 170 GHz into the plasma. The primary functions of the system include plasma start-up, central heating and current drive, and magneto-hydrodynamic instabilities control. The design takes present day technology and extends towards high power CW operation, which represents a large step forward as compared to the present state of the art. The ITER EC system will be a stepping stone to future EC systems for DEMO and beyond. The EC system is faced with significant challenges, which not only includes an advanced microwave system for plasma heating and current drive applications but also has to comply with stringent requirements associated with nuclear safety as ITER became the first fusion device licensed as basic nuclear installations as of 9 November 2012. Since conceptual design of the EC system established in 2007, the EC system has progressed to a preliminary design stage in 2012, and is now moving forward towards a final design. The majority of the subsystems have completed the detailed design and now advancing towards the final design completion.

Progress in the ITER electron cyclotron heating and current drive system design

International Nuclear Information System (INIS)

Omori, Toshimichi; Albajar, Ferran; Bonicelli, Tullio; Carannante, Giuseppe; Cavinato, Mario; Cismondi, Fabio; Darbos, Caroline; Denisov, Grigory; Farina, Daniela; Gagliardi, Mario; Gandini, Franco; Gassmann, Thibault; Goodman, Timothy; Hanson, Gregory; Henderson, Mark A.; Kajiwara, Ken; McElhaney, Karen; Nousiainen, Risto; Oda, Yasuhisa; Oustinov, Alexander

2015-01-01

Highlights: • EC system is designed with an ability to upgrade in power to 28 MW then 40 MW. • The TL is capable of 3 buildings movements; ±15 mm displacements at the worst. • Improved power deposition access injecting 20 MW across nearly the entire plasma. • Ensured nuclear safety by appropriate definition of confinement boundaries. • Proposed I&C architecture for the overall EC plant was successfully reviewed. - Abstract: An electron cyclotron system is one of the four auxiliary plasma heating systems to be installed on the ITER tokamak. The ITER EC system consists of 24 gyrotrons with associated 12 high voltage power supplies, a set of evacuated transmission lines and two types of launchers. The whole system is designed to inject 20 MW of microwave power at 170 GHz into the plasma. The primary functions of the system include plasma start-up, central heating and current drive, and magneto-hydrodynamic instabilities control. The design takes present day technology and extends towards high power CW operation, which represents a large step forward as compared to the present state of the art. The ITER EC system will be a stepping stone to future EC systems for DEMO and beyond. The EC system is faced with significant challenges, which not only includes an advanced microwave system for plasma heating and current drive applications but also has to comply with stringent requirements associated with nuclear safety as ITER became the first fusion device licensed as basic nuclear installations as of 9 November 2012. Since conceptual design of the EC system established in 2007, the EC system has progressed to a preliminary design stage in 2012, and is now moving forward towards a final design. The majority of the subsystems have completed the detailed design and now advancing towards the final design completion.

Progress on HELIAS systems studies

Energy Technology Data Exchange (ETDEWEB)

Warmer, Felix; Beidler, Craig D.; Dinklage, Andreas; Feng, Yuehe; Geiger, Joachim; Schauer, Felix; Turkin, Yuriy; Wolf, Robert; Xanthopoulos, Pavlos [Max-Planck-Institut fuer Plasmaphysik, D-17491 Greifswald (Germany); Kemp, Richard; Knight, Peter; Ward, David [Culham Centre for Fusion Energy, Abingdon, Oxfordshire, OX14 3DB (United Kingdom)

2015-05-01

In order to study and design next-step fusion devices such as DEMO, comprehensive systems codes are commonly employed. For the HELIAS-line, stellarator-specific models have been developed, implemented, and verified within the systems code PROCESS. This systems code ansatz is complemented by self-consistent modeling of plasma scenarios employing a predictive 1-D neoclassical transport code which has been augmented with a model for the edge anomalous transport based on 3-D ITG turbulence simulations. This approach is investigated to ultimately allow one to conduct stellarator system studies, develop design points of HELIAS burning plasma devices, and to facilitate a direct comparison between tokamak and stellarator DEMO and power plant designs. The work reports on the progress towards these goals.

Site safety progress review of spent fuel central interim storage facility. Final report

International Nuclear Information System (INIS)

Gurpinar, A.; Serva, L.; Giuliani

1995-01-01

Following the request of the Czech Power Board (CEZ) and within the scope of the Technical Cooperation Project CZR/9/003, a progress review of the site safety of the Spent Fuel Central Interim Storage Facility (SFCISF) was performed. The review involved the first two stages of the works comprising the regional survey and identification of candidate sites for the underground and surface storage options. Five sites have been identified as a result of the previous works. The following two stages will involved the identification of the preferred candidate sites for the two options and the final site qualification. The present review had the purpose of assessing the work already performed and making recommendations for the next two stages of works

Trends and progress in system identification

CERN Document Server

Eykhoff, Pieter

1981-01-01

Trends and Progress in System Identification is a three-part book that focuses on model considerations, identification methods, and experimental conditions involved in system identification. Organized into 10 chapters, this book begins with a discussion of model method in system identification, citing four examples differing on the nature of the models involved, the nature of the fields, and their goals. Subsequent chapters describe the most important aspects of model theory; the """"classical"""" methods and time series estimation; application of least squares and related techniques for the e

The Michigan high-level radioactive waste program: Final technical progress report

International Nuclear Information System (INIS)

1987-01-01

This report comprises the state of Michigan's final technical report on the location of a proposed high-level radioactive waste disposal site. Included are a list of Michigan's efforts to review the DOE proposal and a detailed report on the application of geographic information systems analysis techniques to the review process

Maryland University sectored isochronous cyclotron (MUSIC): Progress report No. 35

Energy Technology Data Exchange (ETDEWEB)

1986-10-29

Efforts are reported on the installation and checkout of cyclotron components which had been previously fabricated. Final integration of subsystems and major systems leading to internal beam tests is reported near completion. Progress is reported in relation to control system components, focus and steering magnet design, and rf system testing. (LEW)

Final/Progress Report for Instrumentation Grant

International Nuclear Information System (INIS)

None

1997-01-01

The major piece of equipment was a Furnace Model 1000 used during the Nitrate to Ammonia and Ceramic (NAC) process to sinter the ceramic final product. NAC is a new technology to immobilize liquid radioactive waste simulants. The grant also funded related control and measuring equipment

Stratospheric tritium sampling. Final progress report

International Nuclear Information System (INIS)

Mason, A.S.; Oestlund, H.G.

1985-09-01

Stratospheric tritium sampling was part of Project Airstream (sponsored by the US Department of Energy) between 1975 and 1983. Data from the final deployment in November 1983 are reported here, and the results of the 9 years of effort are summarized. 9 refs., 2 figs., 2 tabs

Progress on alternative energy resources

Science.gov (United States)

Couch, H. T.

1982-03-01

Progress in the year 1981 toward the development of energy systems suitable for replacing petroleum products combustion and growing in use to fulfill a near term expansion in energy use is reviewed. Coal is noted to be a potentially heavy pollution source, and the presence of environmentally acceptable methods of use such as fluidized-bed combustion and gasification and liquefaction reached the prototype stage in 1981, MHD power generation was achieved in two U.S. plants, with severe corrosion problems remaining unsolved for the electrodes. Solar flat plate collectors sales amounted to 20 million sq ft in 1981, and solar thermal electric conversion systems with central receivers neared completion. Solar cells are progressing toward DOE goals of $.70/peak W by 1986, while wind energy conversion sales were 2000 machines in 1981, and the industry is regarded as maturing. Finally, geothermal, OTEC, and fusion systems are reviewed.

Design progress of cryogenic hydrogen system for China Spallation Neutron Source

Energy Technology Data Exchange (ETDEWEB)

Wang, G. P.; Zhang, Y.; Xiao, J.; He, C. C.; Ding, M. Y.; Wang, Y. Q.; Li, N.; He, K. [Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, P.R. (China)

2014-01-29

China Spallation Neutron Source (CSNS) is a large proton accelerator research facility with 100 kW beam power. Construction started in October 2011 and is expected to last 6.5 years. The cryogenic hydrogen circulation is cooled by a helium refrigerator with cooling capacity of 2200 W at 20 K and provides supercritical hydrogen to neutron moderating system. Important progresses of CSNS cryogenic system were concluded as follows. Firstly, process design of cryogenic system has been completed including helium refrigerator, hydrogen loop, gas distribution, and safety interlock. Secondly, an accumulator prototype was designed to mitigate pressure fluctuation caused by dynamic heat load from neutron moderation. Performance test of the accumulator has been carried out at room and liquid nitrogen temperature. Results show the accumulator with welding bellows regulates hydrogen pressure well. Parameters of key equipment have been identified. The contract for the helium refrigerator has been signed. Mechanical design of the hydrogen cold box has been completed, and the hydrogen pump, ortho-para hydrogen convertor, helium-hydrogen heat exchanger, hydrogen heater, and cryogenic valves are in procurement. Finally, Hydrogen safety interlock has been finished as well, including the logic of gas distribution, vacuum, hydrogen leakage and ventilation. Generally, design and construction of CSNS cryogenic system is conducted as expected.

Everolimus plus exemestane in postmenopausal patients with HR(+) breast cancer: BOLERO-2 final progression-free survival analysis.

Science.gov (United States)

Yardley, Denise A; Noguchi, Shinzaburo; Pritchard, Kathleen I; Burris, Howard A; Baselga, José; Gnant, Michael; Hortobagyi, Gabriel N; Campone, Mario; Pistilli, Barbara; Piccart, Martine; Melichar, Bohuslav; Petrakova, Katarina; Arena, Francis P; Erdkamp, Frans; Harb, Wael A; Feng, Wentao; Cahana, Ayelet; Taran, Tetiana; Lebwohl, David; Rugo, Hope S

2013-10-01

Effective treatments for hormone-receptor-positive (HR(+)) breast cancer (BC) following relapse/progression on nonsteroidal aromatase inhibitor (NSAI) therapy are needed. Initial Breast Cancer Trials of OraL EveROlimus-2 (BOLERO-2) trial data demonstrated that everolimus and exemestane significantly prolonged progression-free survival (PFS) versus placebo plus exemestane alone in this patient population. BOLERO-2 is a phase 3, double-blind, randomized, international trial comparing everolimus (10 mg/day) plus exemestane (25 mg/day) versus placebo plus exemestane in postmenopausal women with HR(+) advanced BC with recurrence/progression during or after NSAIs. The primary endpoint was PFS by local investigator review, and was confirmed by independent central radiology review. Overall survival, response rate, and clinical benefit rate were secondary endpoints. Final study results with median 18-month follow-up show that median PFS remained significantly longer with everolimus plus exemestane versus placebo plus exemestane [investigator review: 7.8 versus 3.2 months, respectively; hazard ratio = 0.45 (95% confidence interval 0.38-0.54); log-rank P NSAIs. These results further support the use of everolimus plus exemestane in this patient population. ClinicalTrials.gov #NCT00863655.

A Segmented Signal Progression Model for the Modern Streetcar System

Directory of Open Access Journals (Sweden)

Baojie Wang

2015-01-01

Full Text Available This paper is on the purpose of developing a segmented signal progression model for modern streetcar system. The new method is presented with the following features: (1 the control concept is based on the assumption of only one streetcar line operating along an arterial under a constant headway and no bandwidth demand for streetcar system signal progression; (2 the control unit is defined as a coordinated intersection group associated with several streetcar stations, and the control joints must be streetcar stations; (3 the objective function is built to ensure the two-way streetcar arrival times distributing within the available time of streetcar phase; (4 the available time of streetcar phase is determined by timing schemes, intersection structures, track locations, streetcar speeds, and vehicular accelerations; (5 the streetcar running speed is constant separately whether it is in upstream or downstream route; (6 the streetcar dwell time is preset according to historical data distribution or charging demand. The proposed method is experimentally examined in Hexi New City Streetcar Project in Nanjing, China. In the experimental results, the streetcar system operation and the progression impacts are shown to affect transit and vehicular traffic. The proposed model presents promising outcomes through the design of streetcar system segmented signal progression, in terms of ensuring high streetcar system efficiency and minimizing negative impacts on transit and vehicular traffic.

The completed design of the SLC Final Focus System

International Nuclear Information System (INIS)

Murray, J.J.; Brown, K.L.; Fieguth, T.

1987-02-01

The design of the SLC Final Focus System has evolved from its initial conceptual design into its final form. This final design is described including a review of the critical decisions influencing the adoption of particular features. The creation of a feasible design has required that these decisions be tempered by practical considerations such as site constraints, correction of optical errors caused by imperfections, and accommodations requested by engineers and particle detector physicists. As this is the first such system to be built, it is hoped that the experience gained will be useful for the design of future systems

A fuzzy logic expert system for evaluating policy progress towards sustainability goals.

Science.gov (United States)

Cisneros-Montemayor, Andrés M; Singh, Gerald G; Cheung, William W L

2017-12-16

Evaluating progress towards environmental sustainability goals can be difficult due to a lack of measurable benchmarks and insufficient or uncertain data. Marine settings are particularly challenging, as stakeholders and objectives tend to be less well defined and ecosystem components have high natural variability and are difficult to observe directly. Fuzzy logic expert systems are useful analytical frameworks to evaluate such systems, and we develop such a model here to formally evaluate progress towards sustainability targets based on diverse sets of indicators. Evaluation criteria include recent (since policy enactment) and historical (from earliest known state) change, type of indicators (state, benefit, pressure, response), time span and spatial scope, and the suitability of an indicator in reflecting progress toward a specific objective. A key aspect of the framework is that all assumptions are transparent and modifiable to fit different social and ecological contexts. We test the method by evaluating progress towards four Aichi Biodiversity Targets in Canadian oceans, including quantitative progress scores, information gaps, and the sensitivity of results to model and data assumptions. For Canadian marine systems, national protection plans and biodiversity awareness show good progress, but species and ecosystem states overall do not show strong improvement. Well-defined goals are vital for successful policy implementation, as ambiguity allows for conflicting potential indicators, which in natural systems increases uncertainty in progress evaluations. Importantly, our framework can be easily adapted to assess progress towards policy goals with different themes, globally or in specific regions.

Final Performance Progress Report

Energy Technology Data Exchange (ETDEWEB)

Houldin, Joseph [Delaware Valley Industrial Resource Center, Philadelphia, PA (United States); Saboor, Veronica [Delaware Valley Industrial Resource Center, Philadelphia, PA (United States)

2016-03-30

The Accelerator has given the DVIRC an opportunity to get involved in areas of a small and medium-sized manufacturing business that MEP centers typically do not get involved in—the areas of technology development and technical issues. Over the course of the project we’ve come to gain some valuable insights into the market challenges of SMEs, and the market challenges an MEP (such as DVIRC) faces as it seeks to work more deeply and at faster pace on the technology-related aspects of a manufacturing business. For example, while most companies can quantitatively justify investing in an ERP system or a new piece of production equipment, SMEs often struggle with formulating a return-on-investment for advanced technologies. As another example, bringing advanced technology to a company through the individuals interested in the technology (such as engineers or technicians) is not the way to go; as with many MEP services, we need to get to the CEO. And even then, there is a strong reluctance to let outsiders in to these often proprietary areas of the business. As a result of our work in this area, we are now looking more closely at how CEOs that DO invest in advanced technologies justify the investment or make the investment decision. We’ve learned about some of the internal constraints in SMEs that need to be kept in mind as projects get defined and executed—where technical personnel often hinder conversations in this arena rather than contributing value to them. We’ve gained exposure to a new suite of public and private assets that can help us with this work, such as universities and agencies such as NASA. We have also developed relationships with design/engineering companies that can help us as we move more deeply into this area of a company,. Still, defining a technical project takes a huge amount of effort and resources and, once undertaken, has a much longer time trajectory than typical MEP projects. DVIRC field staff and content experts have learned more

Development of Final Running Test System for Digital Systems

Energy Technology Data Exchange (ETDEWEB)

Lee, Kwang-Dae; Lee, Eui-Jong; Lim, Hee-Taek; Kim, Min-Seok [KHNP Central Research Institute, Daejeon (Korea, Republic of)

2016-10-15

In nuclear industry, the newly designed systems to upgrade are qualified to meet IEEE standards and the regulatory guidelines for their functions, performance and reliability requirements. Failure Mode and Effect Analysis, Fault Tree Analysis, and Hazard Analysis have been used to improve the reliability of the control system. To ensure the completeness of the software, the verification and validation processes are carried out during the development process. In spite of the many efforts depending on the analysis and procedures, there are limitations to improve the reliability. The lessons learned from the currently installed system failures show the incompleteness of the final integration test. The current point-to-point and logic-to-logic separate test procedures manually performed by the engineers can cause some procedures missed and have effects on the critical functions. The design processes of the digital systems are met in accordance with the international standards and regulatory guidelines. The lessons learned from the failures of the running digital systems showed the limitations of the current verification and validation efforts. The various improvements and attempts have been considered including the expert review processes and the completeness of the test. In this paper, the Final Running Test Method evaluating the completeness of the digital system using the control patterns and the Test System Architecture are proposed.

Development of Final Running Test System for Digital Systems

International Nuclear Information System (INIS)

Lee, Kwang-Dae; Lee, Eui-Jong; Lim, Hee-Taek; Kim, Min-Seok

2016-01-01

In nuclear industry, the newly designed systems to upgrade are qualified to meet IEEE standards and the regulatory guidelines for their functions, performance and reliability requirements. Failure Mode and Effect Analysis, Fault Tree Analysis, and Hazard Analysis have been used to improve the reliability of the control system. To ensure the completeness of the software, the verification and validation processes are carried out during the development process. In spite of the many efforts depending on the analysis and procedures, there are limitations to improve the reliability. The lessons learned from the currently installed system failures show the incompleteness of the final integration test. The current point-to-point and logic-to-logic separate test procedures manually performed by the engineers can cause some procedures missed and have effects on the critical functions. The design processes of the digital systems are met in accordance with the international standards and regulatory guidelines. The lessons learned from the failures of the running digital systems showed the limitations of the current verification and validation efforts. The various improvements and attempts have been considered including the expert review processes and the completeness of the test. In this paper, the Final Running Test Method evaluating the completeness of the digital system using the control patterns and the Test System Architecture are proposed

Progress on axicell MFTF-B superconducting magnet systems

International Nuclear Information System (INIS)

Wang, S.T.; Kozman, T.A.; Hanson, C.L.; Shimer, D.W.; VanSant, J.H.; Zbasnik, J.

1983-01-01

Since the entire Mirror Fusion Test Facility (MFTF-B) Magnet System was reconfigured from the original A-cell to an axicell design, much progress has been made on the design, fabrication, and installation planning. The axicell MFTF-B magnet array consists of a total of 26 large superconducting main coils. This paper provides an engineering overview of the progress of these coils. Recent studies on the effects of field errors on the plasma at the recircularizing region (transition coils) show that small field errors will generate large displacements of the field lines. These field errors might enhance radial electron heat transport and deteriorate the plasma confinement. Therefore, 16 superconducting trim coils have been designed to correct the coil misalignments. Progress of the trim coils are reported also

Recent progresses in biomedical applications of aptamer-functionalized systems.

Science.gov (United States)

Ding, Fei; Gao, Yangguang; He, Xianran

2017-09-15

Aptamers, known as "chemical antibodies" are screened via a combinational technology of systematic evolution of ligands by exponential enrichment (SELEX). Due to their specific targeting ability, high binding affinity, low immunogenicity and easy modification, aptamer-functionalized systems have been extensively applied in various fields and exhibit favorable results. However, there is still a long way for them to be commercialized, and few aptamer-functionalized systems have yet successfully entered clinical and industrial use. Thus, it is necessary to overview the recent research progresses of aptamer-functionalized systems for the researchers to improve or design novel and better aptamer-functionalized systems. In this review, we first introduce the recent progresses of aptamer-functionalized systems' applications in biosensing, targeted drug delivery, gene therapy and cancer cell imaging, followed by a discussion of the challenges faced with extensive applications of aptamer-functionalized systems and speculation of the future prospects of them. Copyright © 2017 Elsevier Ltd. All rights reserved.

Progress on the data acquisition system at NSCL

International Nuclear Information System (INIS)

Fox, R.; Au, R.; Glynn, T.; Pollack, B.; Vander Mulen, A.

1985-01-01

We report on the progress made in data acquisition software development. Specifically, a unique generalized data routing scheme has been developed which allows user online analysis programs to be safely integrated into the acquisition system without endangering data sent to event recording devices. We describe the structure of the system. Performance is discussed and throughput calculated from it. User experience with the system is also discussed. We show how this routing system may easily be adapted to loosely coupled multiprocessor systems

General method for final focus system design for circular colliders

Directory of Open Access Journals (Sweden)

Riccardo de Maria

2008-03-01

Full Text Available Colliders use final focus systems to reduce the transverse beam sizes at the interaction point in order to increase collision event rates. The maximum focal strength (gradient of the quadrupoles, and the maximum beam size in them, together limit the beam size reduction that is possible. The goal of a final focus system design is to find the best compromise between quadrupole aperture and quadrupole gradient, for the magnet technology that is used. This paper develops a design method that identifies the intrinsic limitations of a final focus system, validates the results of the method against realistic designs, and reports its application to the upgrade of the Large Hadron Collider final focus.

Progressive systemic scleroderma (A case report)

International Nuclear Information System (INIS)

Han, Jung Suh; Kwon, Chung Sik

1974-01-01

This is a report of a rare case of progressive systemic scleroderma involving the skin, lungs, bones, esophagus, duodenum, and colon in a 27 year old Korean female whose chief complaints were generalized edema, knee joint pain, hard and indurated skin lesions on the anterior chest, neck, both upper and lower extremities with loss of pain and touch sensation for one year. A review of literature is submitted

Progressive systemic scleroderma (A case report)

Energy Technology Data Exchange (ETDEWEB)

Han, Jung Suh; Kwon, Chung Sik [Chonnam University College of Medicine, Kwangju (Korea, Republic of)

1974-10-15

This is a report of a rare case of progressive systemic scleroderma involving the skin, lungs, bones, esophagus, duodenum, and colon in a 27 year old Korean female whose chief complaints were generalized edema, knee joint pain, hard and indurated skin lesions on the anterior chest, neck, both upper and lower extremities with loss of pain and touch sensation for one year. A review of literature is submitted.

The stabilisation of final focus system

Indian Academy of Sciences (India)

The StaFF (stabilisation of final focus) system will use interferometers to monitor the relative ... quadrupole magnets will be the most demanding application, where mutual and beam- ... interferometers to measure lines of a geodetic network to record relative motion between two beam ... coupled interferometer design.

Light scattering studies of lower dimensional colloidal particle and critical fluid systems. Final progress report

International Nuclear Information System (INIS)

O'Sullivan, W.J.; Mockler, R.C.

1985-08-01

We have completed a program of small angle scattering Rayleigh linewidth measurements on thin films of a 2,6-lutidine + water mixture. No statistically significant departures from three dimensional dynamic response were seen, although the conditions set by the theory of Calvo and Ferrell were met. We have applied digital image processing to evaluate fractal scale invariance in two dimensional particle aggregates arising from the induced coagulation of colloidal particle monolayer crystals. Our system gives us the capability of calculating the pair correlation function for both small and very large (2 x 10 4 particles) particle clusters. We find evidence of an apparent crossover between kinetic clustering aggregation at small distances (about 20 particle diameters) to percolation or gel/sol transition-behavior at large distances. This is evident in both isolated clusters and in final state ''giant'' aggregates. We are carrying through a parallel program of computer calculations whose motivation is to assess the sensitivity of experimental measures of self similarity to cluster size and image resolution, and to generate efficient algorithms which can be applied to calculate fractal ''critical exponents'' other than the Hausdorff dimension. We have succeeded in measuring the surface tension of a water surface covered by a colloidal particle monolayer crystal, in both its repulsive-dipole and close-packed van der Waals phases

Rooftop PV system. Final technical progress report, Phase II

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-08-01

Under this four-year PV:BONUS Program, ECD and United Solar are developing and demonstrating two new lightweight flexible building integrated Photovoltaic (BIPV) modules specifically designed as exact replacements for conventional asphalt shingles and standing seam metal roofing. These modules can be economically and aesthetically integrated into new residential and commercial buildings, and address the even larger roofing replacement market. The modules are designed to be installed by roofing contractors without special training which minimizes the installation and balance of system costs. The modules will be fabricated from high-efficiency, multiple-junction a-Si alloy solar cells developed by ECD and United Solar. Under the Phase I Program, which ended in March 1994, we developed two different concept designs for rooftop PV modules: (1) the United Solar overlapping (asphalt shingle replacement) shingle-type modules and (2) the ECD metal roof-type modules. We also developed a plan for fabricating, testing and demonstrating these modules. Candidate demonstration sites for our rooftop PV modules were identified and preliminary engineering designs for these demonstrations were developed; a marketing study plan was also developed. The major objectives of the Phase II Program, which started in June 1994 was (1) to develop, test, and qualify these new rooftop modules; (2) to develop mechanical and electrical engineering specifications for the demonstration projects; and (3) to develop a marketing/commercialization plan.

IRIS Final Technical Progress Report

Energy Technology Data Exchange (ETDEWEB)

M. D. Carelli

2003-11-03

OAK-B135 This NERI project, originally started as the Secure Transportable Autonomous Light Water Reactor (STAR-LW) and currently known as the International Reactor Innovative and Secure (IRIS) project, had the objective of investigating a novel type of water-cooled reactor to satisfy the Generation IV goals: fuel cycle sustainability, enhanced reliability and safety, and improved economics. The research objectives over the three-year (1999-2002) program were as follows: First year: Assess various design alternatives and establish main characteristics of a point design; Second year: Perform feasibility and engineering assessment of the selected design solutions; Third year: Complete reactor design and performance evaluation, including cost assessment These objectives were fully attained and actually they served to launch IRIS as a full fledged project for eventual commercial deployment. The program did not terminate in 2002 at the end of the NERI program, and has just entered in its fifth year. This has been made possible by the IRIS project participants which have grown from the original four member, two-countries team to the current twenty members, nine countries consortium. All the consortium members work under their own funding and it is estimated that the value of their in-kind contributions over the life of the project has been of the order of $30M. Currently, approximately 100 people worldwide are involved in the project. A very important constituency of the IRIS project is the academia: 7 universities from four countries are members of the consortium and five more US universities are associated via parallel NERI programs. To date, 97 students have worked or are working on IRIS; 59 IRIS-related graduate theses have been prepared or are in preparation, and 41 of these students have already graduated with M.S. (33) or Ph.D. (8) degrees. This ''final'' report (final only as far as the NERI program is concerned) summarizes the work performed

PV Systems Reliability Final Technical Report.

Energy Technology Data Exchange (ETDEWEB)

Lavrova, Olga [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Flicker, Jack David [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Johnson, Jay [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Armijo, Kenneth Miguel [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gonzalez, Sigifredo [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Schindelholz, Eric John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sorensen, Neil R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Yang, Benjamin Bing-Yeh [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2015-12-01

The continued exponential growth of photovoltaic technologies paves a path to a solar-powered world, but requires continued progress toward low-cost, high-reliability, high-performance photovoltaic (PV) systems. High reliability is an essential element in achieving low-cost solar electricity by reducing operation and maintenance (O&M) costs and extending system lifetime and availability, but these attributes are difficult to verify at the time of installation. Utilities, financiers, homeowners, and planners are demanding this information in order to evaluate their financial risk as a prerequisite to large investments. Reliability research and development (R&D) is needed to build market confidence by improving product reliability and by improving predictions of system availability, O&M cost, and lifetime. This project is focused on understanding, predicting, and improving the reliability of PV systems. The two areas being pursued include PV arc-fault and ground fault issues, and inverter reliability.

Progress Scored in Management Information System at CAS

Institute of Scientific and Technical Information of China (English)

无

2006-01-01

@@ CAS initiative to upgrade its management information system (MIS) is making significant progress. Recently, 116 CAS subordinates have completed their online trial operation of a MIS project at the Academy, called Academia Resource Planning (ARP), marking an important phased achievement of the initiative.

Radioimmunoassay determination of urinary prostaglandins in patients with progressive systemic sclerosis

International Nuclear Information System (INIS)

Ramirez P, P.; Erbessd, M.L.; Mares, G.; Recinos, G.; Graef S, A.; Lavalle, C.

1985-01-01

The results of urinary determinations of E-2 prostaglandines by radioimmunoassay (RIA) in 24-hour urine are presented for three groups: progressive systemic sclerotic patients with normotension and with elevated or normal APR, progressive systemic sclerotic patients with hypertension and with normal or low APR, control group of normal subjects. In a recent report of progressive systemic sclerosis in patients we demonstrated changes in the urine concentratrion of APR levels, sodium excretion and in total blood volume. Based on these findings we felt the need to perform quantifications of E-2 prostaglandines (PGE-2) in 24-hour recently taken urine samples stored at 70 0 and measure the sodium amounts excreted in the urine. We concluded that urinary determination of E-2 prostaglandines was the most suitable for our study as it allowed the establishment of relationships between APR, aldosterone and metabolic sodium balance. (author)

Optimal Tax Depreciation under a Progressive Tax System

NARCIS (Netherlands)

Wielhouwer, J.L.; De Waegenaere, A.M.B.; Kort, P.M.

2000-01-01

The focus of this paper is on the effect of a progressive tax system on optimal tax depreciation. By using dynamic optimization we show that an optimal strategy exists, and we provide an analytical expression for the optimal depreciation charges. Depreciation charges initially decrease over time,

Gallium-67 uptake by the thyroid associated with progressive systemic sclerosis

International Nuclear Information System (INIS)

Sjoberg, R.J.; Blue, P.W.; Kidd, G.S.

1989-01-01

Although thyroidal uptake of gallium-67 has been described in several thyroid disorders, gallium-67 scanning is not commonly used in the evaluation of thyroid disease. Thyroidal gallium-67 uptake has been reported to occur frequently with subacute thyroiditis, anaplastic thyroid carcinoma, and thyroid lymphoma, and occasionally with Hashimoto's thyroiditis and follicular thyroid carcinoma. A patient is described with progressive systemic sclerosis who, while being scanned for possible active pulmonary involvement, was found incidentally to have abnormal gallium-67 uptake only in the thyroid gland. Fine needle aspiration cytology of the thyroid revealed Hashimoto's thyroiditis. Although Hashimoto's thyroiditis occurs with increased frequency in patients with progressive systemic sclerosis, thyroidal uptake of gallium-67 associated with progressive systemic sclerosis has not, to our knowledge, been previously described. Since aggressive thyroid malignancies frequently are imaged by gallium-67 scintigraphy, fine needle aspiration cytology of the thyroid often is essential in the evaluation of thyroidal gallium-67 uptake

Gallium-67 uptake by the thyroid associated with progressive systemic sclerosis

Energy Technology Data Exchange (ETDEWEB)

Sjoberg, R.J.; Blue, P.W.; Kidd, G.S.

1989-01-01

Although thyroidal uptake of gallium-67 has been described in several thyroid disorders, gallium-67 scanning is not commonly used in the evaluation of thyroid disease. Thyroidal gallium-67 uptake has been reported to occur frequently with subacute thyroiditis, anaplastic thyroid carcinoma, and thyroid lymphoma, and occasionally with Hashimoto's thyroiditis and follicular thyroid carcinoma. A patient is described with progressive systemic sclerosis who, while being scanned for possible active pulmonary involvement, was found incidentally to have abnormal gallium-67 uptake only in the thyroid gland. Fine needle aspiration cytology of the thyroid revealed Hashimoto's thyroiditis. Although Hashimoto's thyroiditis occurs with increased frequency in patients with progressive systemic sclerosis, thyroidal uptake of gallium-67 associated with progressive systemic sclerosis has not, to our knowledge, been previously described. Since aggressive thyroid malignancies frequently are imaged by gallium-67 scintigraphy, fine needle aspiration cytology of the thyroid often is essential in the evaluation of thyroidal gallium-67 uptake.

Quantitative application study on the control system of contract progress

International Nuclear Information System (INIS)

Hu Xiaocong; Kang Rujie; Zhan Li

2012-01-01

Quantitative application study on the control system of contract progress, which is based on project management theory and PDCA cycle methods, provides a new way for the contract business management of enterprise, in line with the current situation and the nuclear power enterprise performance management needs. The concept of the system, system development, program design and development of ERP (VBA design) which come from the work experience summary of business managers are convenient and feasible in practical applications. By way of the applications in 2009, 2010, 2011 three-year overhaul contract management and continuous adjustment it has become an important business management tool, which not only effectively guaranteed the contract time and efficiency, but also combines the performance management and contract progress management. This study has provided useful reference for the enterprise management. (authors)

Metaheuristics progress in complex systems optimization

CERN Document Server

Doerner, Karl F; Greistorfer, Peter; Gutjahr, Walter; Hartl, Richard F; Reimann, Marc

2007-01-01

The aim of ""Metaheuristics: Progress in Complex Systems Optimization"" is to provide several different kinds of information: a delineation of general metaheuristics methods, a number of state-of-the-art articles from a variety of well-known classical application areas as well as an outlook to modern computational methods in promising new areas. Therefore, this book may equally serve as a textbook in graduate courses for students, as a reference book for people interested in engineering or social sciences, and as a collection of new and promising avenues for researchers working in this field.

Progressive Systemic sclerosis, manifested like malabsorption syndrome. Case report

International Nuclear Information System (INIS)

Ortiz Piza, Gabriel Jaime; Gonzalez Vasquez, Carlos Mario

2005-01-01

We report the case of a 32 year old woman whose first manifestation of systemic sclerosis was malabsorption syndrome. The small bowel series was the clue to the diagnosis, confirmed by laboratory tests and progression of the disease

Progressive Finland sees progress with nuclear projects

Energy Technology Data Exchange (ETDEWEB)

Dalton, David [NucNet, Brussels (Belgium)

2016-02-15

The Finnish Hanhikivi-1 reactor project is firmly on track and a licence has been granted for construction of a final disposal facility for spent nuclear fuel - the first final repository in the world to enter the construction phase. Significant progress has been made with plans for Finland to build its sixth nuclear reactor unit at Hanhikivi. Fennovoima's licensing manager Janne Liuko said the company expects to receive the construction licence for the Generation III+ Hanhikivi-1 plant in late 2017. The application was submitted to the Finnish Ministry of Employment and the Economy in June 2015.

ESG-CET Final Progress Title

Energy Technology Data Exchange (ETDEWEB)

Don Middleton

2011-10-06

Drawing to a close after five years of funding from DOE's ASCR and BER program offices, the SciDAC-2 project called the Earth System Grid (ESG) Center for Enabling Technologies has successfully established a new capability for serving data from distributed centers. The system enables users to access, analyze, and visualize data using a globally federated collection of networks, computers and software. The ESG software - now known as the Earth System Grid Federation (ESGF) - has attracted a broad developer base and has been widely adopted so that it is now being utilized in serving the most comprehensive multi-model climate data sets in the world. The system is used to support international climate model intercomparison activities as well as high profile U.S. DOE, NOAA, NASA, and NSF projects. It currently provides more than 25,000 users access to more than half a petabyte of climate data (from models and from observations) and has enabled over a 1,000 scientific publications.

Experimental and Theoretical Progress on the GEM Theory

Science.gov (United States)

Brandenburg, J. E.

This paper reports experimental and theoretical progress on the GEM unification theory. In theoretical progress, the derivation of the GEM theory using it in a fully covariant form is achieved based on the principle of self-cancellation of the ZPF EM stress-momentum tensor. This derivation reveals that the final Gravity-EM system obeys a Helmholtz-like equation resembling that governing sound propagation. Finally an improved derivation of the formula for the Newton Gravitation constant is shown, qresulting in the formula G = e2/(4πɛ0 me mp) α exp (-2 (α-.86/σ2…) = 6.673443 x10-11 N-m2 kg-2 that agrees with experimental values to 3 parts per 100,000. Experiments have found parity violating weight reductions in gyroscopes driven by rotating EM fields. These experiments appear to confirm gravity modification using electromagnetism predicted by the GEM theory through the Vacuum Bernoulli Equation.

Progress with the AGR system

International Nuclear Information System (INIS)

Merrett, D.J.

1984-01-01

The AGR programme was initiated in 1965 with the ordering of the Dungeness 'B' reactor, followed by Hinkley point 'B' (1965), Hunterston 'B' (1968), Hartlepool (1970), Heysham I (1970) and the two latest stations at Heysham II and Torness. The paper reviews the achievements and prospects for the AGR system under 6 topic headings. These include: operational experience at Hinkley Point 'B' and Hunterston'B', commissioning of Dungeness 'B', Hartlepool and Heysham I, Heysham II/Torness design, Heysham II/Torness programme and finally future prospects. (U.K.)

Potential of Progressive Construction Systems in Slovakia

Science.gov (United States)

Kozlovska, Maria; Spisakova, Marcela; Mackova, Daniela

2017-10-01

Construction industry is a sector with rapid development. Progressive technologies of construction and new construction materials also called modern methods of construction (MMC) are developed constantly. MMC represent the adoption of construction industrialisation and the use of prefabrication of components in building construction. One of these modern methods is also system Varianthaus, which is based on, insulated concrete forms principle and provides complete production plant for wall, ceiling and roof elements for a high thermal insulation house construction. Another progressive construction system is EcoB, which represents an insulated precast concrete panel based on combination of two layers, insulation and concrete, produced in a factory as a whole. Both modern methods of construction are not yet known and wide-spread in the Slovak construction market. The aim of this paper is focused on demonstration of MMC using potential in Slovakia. MMC potential is proved based on comparison of the selected parameters of construction process - construction costs and construction time. The subject of this study is family house modelled in three material variants - masonry construction (as a representative of traditional methods of construction), Varianthaus and EcoB (as the representatives of modern methods of construction). The results of this study provide the useful information in decision-making process for potential investors of construction.

Work performance and tax compliance in flat and progressive tax systems

NARCIS (Netherlands)

Pantya, Jozsef; Kovacs, Judit; Kogler, C.; Kirchler, Erich

2016-01-01

Different tax systems, and their impact on work motivation and tax compliance are significant issues in contemporary political and economic debates. The proportional feature of a flat tax system is assumed to lead to higher performance, while the fairness of the redistributive progressive tax system

Final Report for File System Support for Burst Buffers on HPC Systems

Energy Technology Data Exchange (ETDEWEB)

Yu, W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Mohror, K. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2017-11-27

Distributed burst buffers are a promising storage architecture for handling I/O workloads for exascale computing. As they are being deployed on more supercomputers, a file system that efficiently manages these burst buffers for fast I/O operations carries great consequence. Over the past year, FSU team has undertaken several efforts to design, prototype and evaluate distributed file systems for burst buffers on HPC systems. These include MetaKV: a Key-Value Store for Metadata Management of Distributed Burst Buffers, a user-level file system with multiple backends, and a specialized file system for large datasets of deep neural networks. Our progress for these respective efforts are elaborated further in this report.

FINAL IMPLEMENTATION AND PERFORMANCE OF THE LHC COLLIMATOR CONTROL SYSTEM

CERN Document Server

Redaelli, S; Masi, A; Losito, R

2009-01-01

The 2008 collimation system of the CERN Large Hadron Collider (LHC) included 80 movable collimators for a total of 316 degrees of freedom. Before beam operation, the final controls implementation was deployed and commissioned. The control system enabled remote control and appropriate diagnostics of the relevant parameters. The collimator motion is driven with time-functions, synchronized with other accelerator systems, which allows controlling the collimator jaw positions with a micrometer accuracy during all machine phases. The machine protection functionality of the system, which also relies on function-based tolerance windows, was also fully validated. The collimator control challenges are reviewed and the final system architecture is presented. The results of the remote system commissioning and the overall performance are discussed.

FOCUS: a fire management planning system -- final report

Science.gov (United States)

Frederick W. Bratten; James B. Davis; George T. Flatman; Jerold W. Keith; Stanley R. Rapp; Theodore G. Storey

1981-01-01

FOCUS (Fire Operational Characteristics Using Simulation) is a computer simulation model for evaluating alternative fire management plans. This final report provides a broad overview of the FOCUS system, describes two major modules-fire suppression and cost, explains the role in the system of gaming large fires, and outlines the support programs and ways of...

Hanford Site pollution prevention progress report; FINAL

International Nuclear Information System (INIS)

BETSCH, M.D.

1999-01-01

The Richland Operations Office (RL) and Office of River Protection (ORP) are pleased to issue the attached Pollution Prevention Progress Report. We have just met the most aggressive waste reduction and A recycling goals to date and are publishing this report to recognize A the site's progress, and to ensure it will sustain success beyond 1 Fiscal Year 2000. This report was designed to inform the been made by RL and ORP in Waste Minimization (WMin) and Pollution Prevention (P2). RL, ORP and their contractors are committed to protecting the environment, and we reiterate pollution prevention should continue to be at the forefront of the environmental cleanup and research efforts. As you read the attached report, we believe you will see a clear demonstration of RL and ORP's outstanding performance as it has been responsible and accountable to the nation, its employees, and the community in which we live and work. commitment that all employees have for environmental stewardship. The report provides useful information about the U.S. Department of Energy's (DOE'S) environmental policy and programs, and contains countless examples of waste minimization projects. This year was the first year our site received the White House Closing the Circle in the category of Affirmative Procurement. This Award recognizes our site for designing a comprehensive strategy for achieving 100 percent purchases of the U.S.Environmenta1 Protection Agency designated recycled items. DOE-Headquarters also acknowledged the site in 1999 for its public outreach efforts in communicating pollution prevention to Hanford Site employees and the community. Our site is truly a recognized leader in outreach as it has kept this title for two consecutive years. In previous years, we received the White House Closing the Circle Honorable Mention in Affirmative Procurement and several other National DOE Awards. Through partnership with the local community and stakeholders, the site and its contractors have a clear

Progress of magnetic-suspension systems and magnetic bearings in the USSR

International Nuclear Information System (INIS)

Kuzin, A.V.

1992-01-01

This paper traces the development and progress of magnetic suspension systems and magnetic bearings in the USSR. The paper describes magnetic bearings for turbomachines, magnetic suspension systems for vibration isolation, some special measuring devices, wind tunnels, and other applications. The design, principles of operation, and dynamic characteristics of the system are presented

High-Efficiency Nitride-Based Solid-State Lighting. Final Technical Progress Report

International Nuclear Information System (INIS)

Paul T. Fini; Shuji Nakamura

2005-01-01

In this final technical progress report we summarize research accomplished during Department of Energy contract DE-FC26-01NT41203, entitled ''High-Efficiency Nitride-Based Solid-State Lighting''. Two teams, from the University of California at Santa Barbara (Principle Investigator: Dr. Shuji Nakamura) and the Lighting Research Center at Rensselaer Polytechnic Institute (led by Dr. N. Narendran), pursued the goals of this contract from thin film growth, characterization, and packaging/luminaire design standpoints. The UCSB team initially pursued the development of blue gallium nitride (GaN)-based vertical-cavity surface-emitting lasers, as well as ultraviolet GaN-based light emitting diodes (LEDs). In Year 2, the emphasis shifted to resonant-cavity light emitting diodes, also known as micro-cavity LEDs when extremely thin device cavities are fabricated. These devices have very directional emission and higher light extraction efficiency than conventional LEDs. Via the optimization of thin-film growth and refinement of device processing, we decreased the total cavity thickness to less than 1 (micro)m, such that micro-cavity effects were clearly observed and a light extraction efficiency of over 10% was reached. We also began the development of photonic crystals for increased light extraction, in particular for so-called ''guided modes'' which would otherwise propagate laterally in the device and be re-absorbed. Finally, we pursued the growth of smooth, high-quality nonpolar a-plane and m-plane GaN films, as well as blue light emitting diodes on these novel films. Initial nonpolar LEDs showed the expected behavior of negligible peak wavelength shift with increasing drive current. M-plane LEDs in particular show promise, as unpackaged devices had unsaturated optical output power of ∼ 3 mW at 200 mA drive current. The LRC's tasks were aimed at developing the subcomponents necessary for packaging UCSB's light emitting diodes, and packaging them to produce a white light

Abnormalities of esophageal and gastric emptying in progressive systemic sclerosis

International Nuclear Information System (INIS)

Maddern, G.J.; Horowitz, M.; Jamieson, G.G.; Chatterton, B.E.; Collins, P.J.; Roberts-Thomson, P.

1984-01-01

Gastric and esophageal emptying were assessed using scintigraphic techniques in 12 patients with progressive systemic sclerosis and 22 normal volunteers. Esophageal emptying was significantly delayed in the patient group, with 7 of the 12 patients beyond the normal range. Gastric emptying was slower in patients than in controls, with 9 patients being outside the normal range for solid emptying and 7 patients outside the normal range for liquid emptying. Findings from gastric and esophageal emptying tests generally correlated well with symptoms of dysphagia and gastroesophageal reflux. However, 2 patients with normal emptying studies had symptomatic heartburn, and 2 patients with delay of both solid and liquid gastric emptying gave no history of gastroesophageal reflux. Delayed gastric emptying may be an important factor in the development of upper gastrointestinal symptoms in patients with progressive systemic sclerosis

Abnormalities of esophageal and gastric emptying in progressive systemic sclerosis

Energy Technology Data Exchange (ETDEWEB)

Maddern, G.J.; Horowitz, M.; Jamieson, G.G.; Chatterton, B.E.; Collins, P.J.; Roberts-Thomson, P.

1984-10-01

Gastric and esophageal emptying were assessed using scintigraphic techniques in 12 patients with progressive systemic sclerosis and 22 normal volunteers. Esophageal emptying was significantly delayed in the patient group, with 7 of the 12 patients beyond the normal range. Gastric emptying was slower in patients than in controls, with 9 patients being outside the normal range for solid emptying and 7 patients outside the normal range for liquid emptying. Findings from gastric and esophageal emptying tests generally correlated well with symptoms of dysphagia and gastroesophageal reflux. However, 2 patients with normal emptying studies had symptomatic heartburn, and 2 patients with delay of both solid and liquid gastric emptying gave no history of gastroesophageal reflux. Delayed gastric emptying may be an important factor in the development of upper gastrointestinal symptoms in patients with progressive systemic sclerosis.

RESEARCH PROGRESS AND HARDWARE SYSTEMS AT DIII-D

Energy Technology Data Exchange (ETDEWEB)

PETERSEN,P.I; THE DIII-D TEAM

2003-10-01

OAK-B135 During the last two years significant progress has been made in the scientific understanding of DIII-D plasmas. Much of this progress has been enabled by the addition of new hardware systems. The electron cyclotron (EC) system has been upgraded from 3 MW to 6 MW, by adding three 1 MW gyrotrons with diamond windows and three steerable launchers (PPPL). The new gyrotrons have been tested to 1.0 MW for 5 s. The system has been used to control the 3/2 and 2/1 neoclassical tearing modes and to locally heat the plasma and thereby indirectly control the current density. Electron cyclotron current drive ECCD has been used to directly affect the current density. A Li-beam diagnostic has been brought on-line for measuring the edge current density using Zeeman splitting. A set of 12 coils (1-coils), consisting of six picture frame coils each above and below the midplane, with a capability of 7 kA for 10 s has been installed inside the DIII-D vessel. These coils, along with the existing six C-coils, are used to apply non-axisymmetric fields to the plasma for both exciting and controlling plasma instabilities. The DIII-D digital plasma control system is now used to not just control the shape and location of the plasma but also the electron temperature, density, the NTMs, RWMs, plasma beta and disruption mitigation. Plasma disruption experiments are extended to mitigation of real time detected disruptions on DIII-D.

Final Report of Strongly Interacting Fermion Systems

International Nuclear Information System (INIS)

Wilkins, J. W.

2001-01-01

There has been significant progress in three broad areas: (A) Optical properties, (B) Large-scale computations, and (C) Many-body systems. In this summary the emphasis is primarily on those papers that point to the research plans. At the same time, some important analytic work is not neglected, some of it even appearing in the description of large-scale Computations. Indeed one of the aims of such computations is to give new insights which lead to development of models capable of simple analytic or nearly analytic analysis

Progress in ISOL target-ion source systems

Energy Technology Data Exchange (ETDEWEB)

Koester, U. [Institut Laue Langevin, 6 Rue Jules Horowitz, F-38042 Grenoble Cedex 9 (France); ISOLDE, CERN, CH-1211 Geneve 23 (Switzerland)], E-mail: koester@ill.fr; Arndt, O. [HGF VISTARS and Institut fuer Kernchemie, Johannes-Gutenberg Universitaet Mainz, D-55128 Mainz (Germany); Bouquerel, E.; Fedoseyev, V.N. [ISOLDE, CERN, CH-1211 Geneve 23 (Switzerland); Franberg, H. [ISOLDE, CERN, CH-1211 Geneve 23 (Switzerland); Laboratory for Radio- and Environmental Chemistry, Paul Scherrer Institut, CH-5232 Villigen PSI (Switzerland); Joinet, A. [ISOLDE, CERN, CH-1211 Geneve 23 (Switzerland); Centre d' Etude Spatiale des Rayonnements, 9 Av. du Colonel Roche, F-31028 Toulouse Cedex 4 (France); Jost, C. [HGF VISTARS and Institut fuer Kernchemie, Johannes-Gutenberg Universitaet Mainz, D-55128 Mainz (Germany); Kerkines, I.S.K. [Laboratory of Physical Chemistry, National and Kapodistrian University of Athens, Department of Chemistry, Zografou 157 71, GR (Greece); Cherry L. Emerson Center for Scientific Computation and Department of Chemistry, Emory University, Atlanta, GA 30322 (United States); Kirchner, R. [Gesellschaft fuer Schwerionenforschung, Planckstr. 1, D-64291 Darmstadt (Germany)

2008-10-15

The heart of every ISOL (isotope separation on-line) facility is its target and ion source system. Its efficiency, selectivity and rapidity is decisive for the production of intense and pure ion beams of short-lived isotopes. Recent progress in ISOL target and ion source technology is discussed at the examples of radioactive ion beams of exotic zinc and tin isotopes that were purified by isothermal chromatography and molecular sideband separation respectively. An outlook is given to which other elements these purification methods are applicable.

Progress in ISOL target-ion source systems

International Nuclear Information System (INIS)

Koester, U.; Arndt, O.; Bouquerel, E.; Fedoseyev, V.N.; Franberg, H.; Joinet, A.; Jost, C.; Kerkines, I.S.K.; Kirchner, R.

2008-01-01

The heart of every ISOL (isotope separation on-line) facility is its target and ion source system. Its efficiency, selectivity and rapidity is decisive for the production of intense and pure ion beams of short-lived isotopes. Recent progress in ISOL target and ion source technology is discussed at the examples of radioactive ion beams of exotic zinc and tin isotopes that were purified by isothermal chromatography and molecular sideband separation respectively. An outlook is given to which other elements these purification methods are applicable.

SatisFactory Final System Evaluation Report

OpenAIRE

Sunlight SA

2018-01-01

The present document is a deliverable of the SatisFactory project, funded by the European Commission’s Directorate-General for Research and Innovation (DG RTD), under its Horizon 2020 Research and innovation programme (H2020). The main objective of this deliverable is to report on the SatisFactory Final System Evaluation, with regards to the industrial pilots at COMAU and SUNLIGHT. The evaluation of SatisFactory platform is based on the implementation of the business scenarios where each tool...

Low cost solar array project. Quarterly progress report, January-March, 1981

Energy Technology Data Exchange (ETDEWEB)

1981-01-01

The engineering design, fabrication, assembly, operation, economic analysis, and process support R and D for an Experimental Process System Development Unit (EPSDU) are presented. The civil construction work was completed and the mechanical bid package is in preparation. The electrical design effort is in progress. Parallel efforts which complement the mechanical design are the process flow diagrams and control instrumentation logic for startup operation and shutdown. These are in progress and will identify all process and utility streams, control systems, and flow logic. The data collection system takes the signals from the instrumentation, translates them into engineering units and finally develops a data report which summarizes all key performance parameters. Cleaning procedures have been established to assure a contamination-free product and inspection visits have been made to the fabricators of specialty equipment.

Implementing a Progressive Consumption Tax: Advantages of Adopting the VAT Credit-Method System

OpenAIRE

Grinberg, Itai

2006-01-01

A credit–method value–added tax, a payroll tax, and a business–level wage subsidy can approximate the economic and distributional consequences of a subtraction–method X–tax. Such a credit–method progressive consumption tax has administrative advantages as compared to a subtraction–method progressive consumption tax, once certain political factors are taken into account. Further, unlike a subtraction–method system, a credit–method progressive consumption tax could easily interact with other ta...

[Hepatobiliary System Diseases as the Predictors of Psoriasis Progression].

Science.gov (United States)

Smirnova, S V; Barilo, A A; Smolnikova, M V

2016-01-01

To assess the state of the hepatobiliary system in psoriasis andpsoriatic arthritis in order to establish a causal relationship and to identify clinical and functional predictors of psoriatic disease progression. The study includedpatients with extensive psoriasis vulgaris (n = 175) aged 18 to 66 years old and healthy donors (n = 30), matched by sex and age: Group 1--patients with psoriasis (PS, n = 77), group 2--patients with psoriatic arthritis (PsA, n = 98), group 3--control. The evaluation of functional state of the hepatobiliary system was performed by the analysis of the clinical and anamnestic data and by the laboratory-instrumental methods. We identified predictors of psoriasis: triggers (stress and nutritionalfactor), increased total bilirubin, aspartate aminotransferase, alkaline phosphatase, gamma-glutamyl transferase, eosinophilia, giardiasis, carriers of hepatitis C virus, ductal changes andfocal leisons in the liver, thickening of the walls of the gallbladder detected by ultrasound. Predictors ofpsoriatic arthritis: age over 50 years, dyspeptic complaints, the presence of hepatobiliary system diseases, the positive right hypochondrium syndrome, the clinical symptoms of chronic cholecystitis, excess body weight, high levels of bilirubin, cholesterol and low density lipoprotein, hepatomegaly, non-alcoholic fatty liver disease. High activity of hepatocytes cytolysis, cholestasis, inflammation, metabolic disorders let us considerpsoriatic arthritis as a severe clinical stage psoriatic disease when the hepatobiliary system, in turn, is one of the main target organs in systemic psoriatic process. Non-alcoholic fatty liver disease and chronic cholecystitis are predictors of psoriatic disease progression.

Behavioral-Progress Monitoring Using the Electronic Daily Behavioral Report Card (e-DBRC) System

Science.gov (United States)

Burke, Mack D.; Vannest, Kimberly J.

2008-01-01

In this article, the authors present an overview of a Web-based electronic system for behavioral-progress monitoring. Behavioral-progress monitoring is necessary to evaluate responsiveness to behavioral interventions, the effects of positive behavioral support, and the attainment of individualized education program goals and objectives. The…

Operations-oriented performance measures for freeway management systems : final report.

Science.gov (United States)

2008-12-01

This report describes the second and final year activities of the project titled Using Operations-Oriented Performance Measures to Support Freeway Management Systems. Work activities included developing a prototype system architecture for testi...

ASBESTOS PIPE-INSULATION REMOVAL ROBOT SYSTEM; FINAL

International Nuclear Information System (INIS)

Unknown

2000-01-01

This final topical report details the development, experimentation and field-testing activities for a robotic asbestos pipe-insulation removal robot system developed for use within the DOE's weapon complex as part of their ER and WM program, as well as in industrial abatement. The engineering development, regulatory compliance, cost-benefit and field-trial experiences gathered through this program are summarized

Plant systems/components modularization study. Final report

International Nuclear Information System (INIS)

1977-07-01

The final results are summarized of a Plant Systems/Components Modularization Study based on Stone and Webster's Pressurized Water Reactor Reference Design. The program has been modified to include evaluation of the most promising areas for modular consideration based on the level of the Sundesert Project engineering design completion and the feasibility of their incorporation into the plant construction effort

The Final Focus Test Beam laser referene system

International Nuclear Information System (INIS)

Bressler, V.E.; Ruland, R.E.

1993-05-01

The original design for the SLAC linac included an alignment reference system with 270 diffraction gratings situated along the 3000 meter linac. These gratings have provided SLAC with a global reference line repeatable to within 200 micro meters. For the Final Focus Test Beam, this laser system has been extended and 13 new diffraction gratings have been installed. Improvements targets and the availability of new instruments allows us to evaluate the performance of the laser reference system at the 510 micro meter level. An explanation of the system and the results of our evaluation are presented

Initial Progress Rates as Related to Performance in a Personalized System of Instruction

Science.gov (United States)

Henneberry, John K.

1976-01-01

Discusses research which explored the hypothesis that students who are fast starters in a personalized system of instruction psychology course would perform better and maintain faster course progress rates than slow starters. Findings indicate that students' starting pace is predictive of course performance and subsequent progress rates.…

The progressive tax

OpenAIRE

Estrada, Fernando

2010-01-01

This article describes the argumentative structure of Hayek on the relationship between power to tax and the progressive tax. It is observed throughout its work giving special attention to two works: The Constitution of Liberty (1959) and Law, Legislation and Liberty, vol3; The Political Order of Free People, 1979) Hayek describes one of the arguments most complete information bout SFP progressive tax systems (progressive tax). According to the author the history of the tax progressive system...

Mefloquine improved progressive multifocal leukoencephalopathy in a patient with systemic lupus erythematosus.

Science.gov (United States)

Beppu, Minako; Kawamoto, Michi; Nukuzuma, Souichi; Kohara, Nobuo

2012-01-01

We describe a case of a 67-year-old man with systemic lupus erythematosus who presented with progressive left hemiplegia. Although the cerebral spinal fluid (CSF) polymerase chain reaction (PCR) for the JC virus was negative, a brain biopsy confirmed the diagnosis of progressive multifocal leukoencephalopathy (PML). The tapering of prednisone and the use of cidofovir could not arrest the disease progression. Administration of mefloquine stopped the extension of the lesion, and resulted in obvious clinical improvement. The CSF nested PCR for the JC virus also became negative. This widely used drug should be tried for the treatment of non-HIV PML.

Strongly interacting fermion systems. Progress report, November 15, 1994--November 14, 1995

International Nuclear Information System (INIS)

1994-01-01

This paper is the progress report for the period November 15, 1993 to November 14, 1994 for a program which relates to studies of strongly interacting fermion systems. The author has made significant progress in three areas, which are discussed in the report. These are: (1) optical properties in the open-quotes electronic structure program,close quotes calculating optical properties of quartz and urea; (2) quasi-one-dimensional systems, discussing the tuning of the large-density-wave or Peierls distortion in transition-metal linear chain compounds and the universal subgap optical absorptance of classes of quasi-one-dimensional compounds; and (3) other strongly interaction fermion systems, emphasizing the study of the effect of many-body interactions on the low-temperature properties of metals and superconductors

Cosmological Final Focus Systems

International Nuclear Information System (INIS)

Irwin, J

2004-01-01

We develop the many striking parallels between the dynamics of light streams from distant galaxies and particle beams in accelerator final focus systems. Notably the deflections of light by mass clumps are identical to the kicks arising from the long-range beam-beam interactions of two counter-rotating particle beams (known as parasitic crossings). These deflections have sextupolar as well as quadrupolar components. We estimate the strength of such distortions for a variety of circumstances and argue that the sextupolar distortions from clumping within clusters may be observable. This possibility is enhanced by the facts that (1) the sextupolar distortions of background galaxies is a factor of 5 smaller than the quadrupolar distortion, (2) the angular orientation of the sextupolar and quadrupolar distortions from a mass distribution would be correlated, appearing as a slightly curved image, (3) these effects should be spatially clumped on the sky

Biorefinery Demonstration Project Final Progress Report

Energy Technology Data Exchange (ETDEWEB)

Lee, David [University of Georgia Research Foundation, Inc., Athens, GA (United States)

2015-10-20

In this project we focused on various aspects of biorefinery technology development including algal-biorefinery technology, thermochemical conversion of biomass to bio-oils and biochar; we tested characteristics and applications of biochars and evaluated nutrient cycling with wastewater treatment by the coupling of algal culture systems and anaerobic digestion. Key results include a method for reducing water content of bio-oil through atomized alcohol addition. The effect included increasing the pH and reducing the viscosity and cloud point of the bio-oil. Low input biochar production systems were evaluated via literature reviews and direct experimental work. Additionally, emissions were evaluated and three biochar systems were compared via a life cycle analysis. Attached growth systems for both algal cultivation and algal harvesting were found to be superior to suspended growth cultures. Nutrient requirements for algal cultivation could be obtained by the recycling of anaerobic digester effluents, thus experimentally showing that these two systems could be directly coupled. Twenty-two journal articles and six intellectual property applications resulted from the cumulative work that this project contributed to programmatically.

[The glymphatic system: concept, function and research progresses].

Science.gov (United States)

Wang, Lin-Hui; Wang, Zi-Lan; Chen, Wen-Yue; Chen, Ming-Jia; Xu, Guang-Yin

2018-02-25

The glymphatic system is a cerebrospinal fluid-interstitial fluid exchange system dependent on the water channel aquaporin-4 polarized on astrocyte endfeet, which is proposed to account for the clearance of abnormal proteins (e.g. β-amyloid) and metabolites (e.g. lactate) from the brain. Accumulating studies have revealed that glymphatic activity during sleep and general anesthesia is dramatically enhanced, while its function is significantly damaged during aging, traumatic brain injury, Alzheimer's disease, stroke, and diabetes. The glymphatic hypothesis is a breakthrough in the field of neuroscience recently, which would considerably enhance our comprehension on the cerebrospinal fluid circulation and its role in the maintenance of brain homeostasis. In this review, we briefly introduced the conceptualization of glymphatic system, summarized the recent progresses, and prospected its future investigation and potential clinical application.

Simulation-based expert system for nuclear reactor control and diagnostics. Progress report

International Nuclear Information System (INIS)

Lee, J.C.; Martin, W.R.

1986-01-01

This research concerns the development of artificial intelligence (AI) techniques suitable for application to the diagnostics and control of nuclear power plant systems. The overall objective of the current effort is to build a prototype simulation-based expert system for diagnosing accidents in nuclear reactors. The system is being designed to analyze plant data heuristically using fuzzy logic to form a set of hypotheses about a particular transient. Hypothesis testing, fault magnitude estimation and transient analysis is performed using simulation programs to model plant behavior. An adaptive learning technique has been developed for achieving accurate simulations of plant dynamics using low-order physical models of plant components. The results of the diagnostics and simulation analysis of the plant transient are to be analyzed by an expert system for final diagnoses and control guidance. To date, significant progress has been made toward achieving the primary goals of this project. Based on a critical safety functions approach, an overall design for the nuclear plant expert system has been developed. The methodology for performing diagnostic reasoning on plant signals has been developed and the algorithms implemented and tested. A methodology for utilizing the information contained in the physical models of plant components has also been developed. This work included the derivation of a unique Kalman filtering algorithm for using power plant data to systematically improve on-line simulations through the judicious adjustment of key model parameters. A few simulation models of key plant components have been developed and implemented to demonstrate the method on a realistic accident scenario. The chosen transient is a loss of feed flow exasperated by a stuck open relief valve, similar to the initiating event of the Three Mile Island Unit 2 accident in 1979

Progress in Aluminum Electrolysis Control and Future Direction for Smart Aluminum Electrolysis Plant

Science.gov (United States)

Zhang, Hongliang; Li, Tianshuang; Li, Jie; Yang, Shuai; Zou, Zhong

2017-02-01

The industrial aluminum reduction cell is an electrochemistry reactor that operates under high temperatures and highly corrosive conditions. However, these conditions have restricted the measurement of key control parameters, making the control of aluminum reduction cells a difficult problem in the industry. Because aluminum electrolysis control systems have a significant economic influence, substantial research has been conducted on control algorithms, control systems and information systems for aluminum reduction cells. This article first summarizes the development of control systems and then focuses on the progress made since 2000, including alumina concentration control, temperature control and electrolyte molecular ratio control, fault diagnosis, cell condition prediction and control system expansion. Based on these studies, the concept of a smart aluminum electrolysis plant is proposed. The frame construction, key problems and current progress are introduced. Finally, several future directions are discussed.

Optimal tax depreciation under a progressive tax system

OpenAIRE

Wielhouwer, J.L.; De Waegenaere, A.M.B.; Kort, P.M.

2002-01-01

The focus of this paper is on the effect of a progressive tax system on optimal tax depreciation. By using dynamic optimization we show that an optimal strategy exists, and we provide an analytical expression for the optimal depreciation charges. Depreciation charges initially decrease over time, and after a number of periods the firm enters a steady state where depreciation is constant and equal to replacement investments. This way, the optimal solution trades off the benefits of accelerated...

Beam dynamics in the SLC final focus system

International Nuclear Information System (INIS)

Bambade, P.S.

1987-06-01

The SLC luminosity is reached by colliding beams focused to about 2 μm transverse sizes. The Final Focus System (FFS) must enable, beyond its basic optical design, the detection and correction of errors accumulated in the system. In this paper, after summarizing the design, we review the sensitivity to such errors and the ability to correct them. The overall tuning strategy involves three phases: single beam spot minimization, steering the beams in collision and luminosity optimization with beam-beam effects

Road Transportable Analytical Laboratory (RTAL) system. Quarterly progress report, May 1994--July 1994

International Nuclear Information System (INIS)

1994-01-01

Progress achieved on the development of the RTAL system during the quarter, May 1 through July 31, 1994 is reported. The work included NEPA analysis, drawings, prototype system construction, and on-site prototype demonstration

Probing LINEAR Collider Final Focus Systems in SuperKEKB

CERN Document Server

Thrane, Paul Conrad Vaagen

2017-01-01

A challenge for future linear collider final focus systems is the large chromaticity produced by the final quadrupoles. SuperKEKB will be correcting high levels of chromaticity using the traditional scheme which has been also proposed for the CLIC FFS. We present early simulation results indicating that lowering β*у in the SuperKEKB Low Energy Ring might be possible given on-axis injection and low bunch current, opening the possibility of testing chromaticity correction beyond FFTB level, similar to ILC and approaching that of CLIC. CLIC – Note – 1077

A RECIPE FOR LINEAR COLLIDER FINAL FOCUS SYSTEM DESIGN

International Nuclear Information System (INIS)

Seryi, Andrei

2003-01-01

The design of Final Focus systems for linear colliders is challenging because of the large demagnifications needed to produce nanometer-sized beams at the interaction point. Simple first- and second-order matrix matching have proven insufficient for this task, and minimization of third- and higher-order aberrations is essential. An appropriate strategy is required for the latter to be successful. A recipe for Final Focus design, and a set of computational tools used to implement this approach, are described herein. An example of the use of this procedure is given

[Research progress of co-culture system for constructing vascularized tissue engineered bone].

Science.gov (United States)

Fu, Weili; Xiang, Zhou

2014-02-01

To review the research progress of the co-culture system for constructing vascularized tissue engineered bone. The recent literature concerning the co-culture system for constructing vascularized tissue engineered bone was reviewed, including the selection of osteogenic and endothelial lineages, the design and surface modification of scaffolds, the models and dimensions of the co-culture system, the mechanism, the culture conditions, and their application progress. The construction of vascularized tissue engineered bone is the prerequisite for their survival and further clinical application in vivo. Mesenchymal stem cells (owning the excellent osteogenic potential) and endothelial progenitor cells (capable of directional differentiation into endothelial cell) are considered as attractive cell types for the co-culture system to construct vascularized tissue engineered bone. The culture conditions need to be further optimized. Furthermore, how to achieve the clinical goals of minimal invasion and autologous transplantation also need to be further studied. The strategy of the co-culture system for constructing vascularized tissue engineered bone would have a very broad prospects for clinical application in future.

Research and development on super heat pump energy accumulation system. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1993-06-01

This is the final report on research and development of super heat pump energy accumulation system, which has been carried out from FY 1985 to 1992. It describes outline of the research and development program, R and D results, final evaluation methodology, evaluation of the R and D, proposals for the commercialization, and so on. The super high performance compression heat pumps are technically evaluated for highly efficient type (for heating, and cooling and heating), high temperature type (utilizing high temperature heat source, and low temperature heat source), working fluids (alcohol-based and nonalcohol-based), stainless steel plate fin type heat exchanger, EHD heat exchanger, and so on. The other techniques evaluated include those for chemical heat storage, combined systems, plant simulation, and systemization. The evaluation works are also directed to the economic and environmental aspects. Finally, the R and D themes are proposed to leap over various hurdles, e.g., reliability and economic viability, for the eventual commercialization of the energy accumulation system. (NEDO)

67Gallium lung scans in progressive systemic sclerosis

International Nuclear Information System (INIS)

Baron, M.; Feiglin, D.; Hyland, R.; Urowitz, M.B.; Shiff, B.

1983-01-01

67 Gallium lung scans were performed in 19 patients with progressive systemic sclerosis (scleroderma). Results were expressed quantitatively as the 67 Gallium Uptake Index. The mean total pulmonary 67 Gallium Uptake Index in patients was significantly higher than that in controls (41 versus 25), and 4 patients (21%) fell outside the normal range. There were no clinical or laboratory variables that correlated with the 56 Gallium uptake. Increased pulmonary 67 Gallium uptake in scleroderma may prove useful as an index of pulmonary disease activity

1985. Annual progress report

International Nuclear Information System (INIS)

1986-01-01

This annual progress report of the CEA Protection and Nuclear Safety Institut outlines a description of the progress made in each sections of the Institut Research activities of the different departments include: reactor safety analysis, fuel cycle facilities analysis; and associated safety research programs (criticality, sites, transport ...), radioecology and environmental radioprotection techniques; data acquisition on radioactive waste storage sites; radiation effects on man, studies on radioprotection techniques; nuclear material security including security of facilities, security of nuclear material transport, and monitoring of nuclear material management; nuclear facility decommissioning; and finally the public information [fr

Multi-Point Combustion System: Final Report

Science.gov (United States)

Goeke, Jerry; Pack, Spencer; Zink, Gregory; Ryon, Jason

2014-01-01

A low-NOx emission combustor concept has been developed for NASA's Environmentally Responsible Aircraft (ERA) program to meet N+2 emissions goals for a 70,000 lb thrust engine application. These goals include 75 percent reduction of LTO NOx from CAEP6 standards without increasing CO, UHC, or smoke from that of current state of the art. An additional key factor in this work is to improve lean combustion stability over that of previous work performed on similar technology in the early 2000s. The purpose of this paper is to present the final report for the NASA contract. This work included the design, analysis, and test of a multi-point combustion system. All design work was based on the results of Computational Fluid Dynamics modeling with the end results tested on a medium pressure combustion rig at the UC and a medium pressure combustion rig at GRC. The theories behind the designs, results of analysis, and experimental test data will be discussed in this report. The combustion system consists of five radially staged rows of injectors, where ten small scale injectors are used in place of a single traditional nozzle. Major accomplishments of the current work include the design of a Multipoint Lean Direct Injection (MLDI) array and associated air blast and pilot fuel injectors, which is expected to meet or exceed the goal of a 75 percent reduction in LTO NOx from CAEP6 standards. This design incorporates a reduced number of injectors over previous multipoint designs, simplified and lightweight components, and a very compact combustor section. Additional outcomes of the program are validation that the design of these combustion systems can be aided by the use of Computational Fluid Dynamics to predict and reduce emissions. Furthermore, the staging of fuel through the individually controlled radially staged injector rows successfully demonstrated improved low power operability as well as improvements in emissions over previous multipoint designs. Additional comparison

[Physical properties of f electron systems]: Progress report, February 1987-January 1988

International Nuclear Information System (INIS)

Riseborough, P.S.

1988-01-01

This paper discusses the progress in research on f electron systems. The major properties discussed in this paper are: magnetic properties, transport properties, heavy fermion superconductivity, and photo-emission spectroscopy

Who pays for healthcare in Bangladesh? An analysis of progressivity in health systems financing.

Science.gov (United States)

Molla, Azaher Ali; Chi, Chunhuei

2017-09-06

The relationship between payments towards healthcare and ability to pay is a measure of financial fairness. Analysis of progressivity is important from an equity perspective as well as for macroeconomic and political analysis of healthcare systems. Bangladesh health systems financing is characterized by high out-of-pocket payments (63.3%), which is increasing. Hence, we aimed to see who pays what part of this high out-of-pocket expenditure. To our knowledge, this was the first progressivity analysis of health systems financing in Bangladesh. We used data from Bangladesh Household Income and Expenditure Survey, 2010. This was a cross sectional and nationally representative sample of 12,240 households consisting of 55,580 individuals. For quantification of progressivity, we adopted the 'ability-to-pay' principle developed by O'Donnell, van Doorslaer, Wagstaff, and Lindelow (2008). We used the Kakwani index to measure the magnitude of progressivity. Health systems financing in Bangladesh is regressive. Inequality increases due to healthcare payments. The differences between the Gini coefficient and the Kakwani index for all sources of finance are negative, which indicates regressivity, and that financing is more concentrated among the poor. Income inequality increases due to high out-of-pocket payments. The increase in income inequality caused by out-of-pocket payments is 89% due to negative vertical effect and 11% due to horizontal inequity. Our findings add substantial evidence of health systems financing impact on inequitable financial burden of healthcare and income. The heavy reliance on out-of-pocket payments may affect household living standards. If the government and people of Bangladesh are concerned about equitable financing burden, our study suggests that Bangladesh needs to reform the health systems financing scheme.

Model-based setup assistant for progressive tools

Science.gov (United States)

Springer, Robert; Gräler, Manuel; Homberg, Werner; Henke, Christian; Trächtler, Ansgar

2018-05-01

In the field of production systems, globalization and technological progress lead to increasing requirements regarding part quality, delivery time and costs. Hence, today's production is challenged much more than a few years ago: it has to be very flexible and produce economically small batch sizes to satisfy consumer's demands and avoid unnecessary stock. Furthermore, a trend towards increasing functional integration continues to lead to an ongoing miniaturization of sheet metal components. In the industry of electric connectivity for example, the miniaturized connectors are manufactured by progressive tools, which are usually used for very large batches. These tools are installed in mechanical presses and then set up by a technician, who has to manually adjust a wide range of punch-bending operations. Disturbances like material thickness, temperatures, lubrication or tool wear complicate the setup procedure. In prospect of the increasing demand of production flexibility, this time-consuming process has to be handled more and more often. In this paper, a new approach for a model-based setup assistant is proposed as a solution, which is exemplarily applied in combination with a progressive tool. First, progressive tools, more specifically, their setup process is described and based on that, the challenges are pointed out. As a result, a systematic process to set up the machines is introduced. Following, the process is investigated with an FE-Analysis regarding the effects of the disturbances. In the next step, design of experiments is used to systematically develop a regression model of the system's behaviour. This model is integrated within an optimization in order to calculate optimal machine parameters and the following necessary adjustment of the progressive tool due to the disturbances. Finally, the assistant is tested in a production environment and the results are discussed.

Final Progress Report: SPECT Assay of Radiolabeled Monoclonal Antibodies

International Nuclear Information System (INIS)

Jaszczak, Ronald J.

2004-01-01

During the past project period, we proposed to collaborate closely with DOE's Thomas Jefferson National Accelerator Facility (Jefferson Lab or JLab) to design a compact, ultra-high-resolution, high-sensitivity gamma camera for quantifying brain-tumor distributions of I-131. We also proposed to continue our on-going research in developing and evaluating pinhole collimation for quantitative ultra-high-resolution imaging of I-131-labeled MAbs. We have made excellent progress in accomplishing much of the research related to pinhole collimation. Many of the most significant results have been presented in peer-reviewed journal articles and conference proceedings. We have also made good progress in collaborating with JLab's Detector Group in developing a compact, ultra-high-resolution, gamma camera. A prototype I-131 imager was delivered to Duke on May 28, 2003. Our research results are summarized in the following sections. A. JLAB-DUKE DEDICATED BRAIN-TUMOR IMAGING SYSTEM A.1. Determination of Optimal Collimator Design During the current project period a prototype I-131 dedicated brain imager has been designed and built. Computer simulations and analysis of alternate designs were performed at Duke to determine an optimal collimator design. Collimator response was characterized by spatial resolution and sensitivity. Both geometric (non-penetrative) and penetrative sensitivities were considered in selecting an optimal collimator design. Based on these simulation results, two collimator designs were selected and built by external vendors. Initial imaging results were obtained using these collimators. B. INITIAL DEVELOPMENT OF SPECT RECONSTRUCTION SOFTWARE FOR JLAB-DUKE CAMERA B.1. Modeling Thick Septa and Collimator Holes: Geometrical-Phantom Study A geometrical phantom was designed to illuminate spatial resolution effects. The phantom includes a uniformly attenuating medium that consists of all voxels within an elliptical cylinder that is centered on the axis of rotation

The theory of hadronic systems. Annual progress report

International Nuclear Information System (INIS)

Gibbs, W.R.

1993-01-01

This report briefly discusses progress on the following topics: isospin breaking in the pion-nucleon system; direct capture of pions into deeply bound atomic states; knock out of secondary components in the nucleus; study of the radii of neutron distributions in nuclei; the hadronic double scattering operator; transparency in pion production; asymmetry in pion scattering and charge exchange from polarized nuclei; the mechanism of pion absorption in nuclei; the neutron-proton charge-exchange reaction; modification of the fundamental structure of nucleons in nuclei; and antiproton annihilation in nuclei

Radiology of the hand in progressive systemic sclerosis

Energy Technology Data Exchange (ETDEWEB)

Scutellari, P N; Orzincolo, C; Delli Gatti, I. and others

1986-01-01

Radiographs and xerographs of the hands of 35 patients with progressive systematic sclerosis (PSS), as defined by the ARA, were reviewed. Patients with ''overlap'' syndromes (i.e., mixed connective tissue disease, systemic lupus erythematosus or rheumatoid arthritis) have been excluded. Soft tissue changes included atrophy (hidebound skin), and dystrophic calcifications, particularly in CREST patients (calcinosis, Raynaud phenomenon, esophageal dysmobility, sclerodactily and telangectasia). The most common bony change is resorption of distal phalanges; diffuse osteoporosis is also frequent; the distal interphalangeal and first carpometacarpal joints involvement appear as a distinctive feature of this e....

Plant systems/components modularization study. Final report. [PWR

Energy Technology Data Exchange (ETDEWEB)

1977-07-01

The final results are summarized of a Plant Systems/Components Modularization Study based on Stone and Webster's Pressurized Water Reactor Reference Design. The program has been modified to include evaluation of the most promising areas for modular consideration based on the level of the Sundesert Project engineering design completion and the feasibility of their incorporation into the plant construction effort.

Brayton isotope power system, phase I. Final report

International Nuclear Information System (INIS)

1978-01-01

The Phase I program resulted in the development and ground demonstration of a dynamic power conversion system. The two key contractual objectives of 25% conversion efficiency and 1000 h of endurance testing were successfully met. As a result of the Phase I effort, the BIPS is a viable candidate for further development into a flight system capable of sustained operation in space. It represents the only known dynamic space power system to demonstrate the performance and endurance coupled with the simplicity necessary for reliable operation. This final report follows thirty-five monthly reports. For expediency, it makes liberal use of referenced documents which have been submitted to DOE during the course of the program

Development of a Learning Progression for the Formation of the Solar System

Science.gov (United States)

Plummer, Julia D.; Palma, Christopher; Flarend, Alice; Rubin, KeriAnn; Ong, Yann Shiou; Botzer, Brandon; McDonald, Scott; Furman, Tanya

2015-01-01

This study describes the process of defining a hypothetical learning progression (LP) for astronomy around the big idea of "Solar System formation." At the most sophisticated level, students can explain how the formation process led to the current Solar System by considering how the planets formed from the collapse of a rotating cloud of…

The tumor macroenvironment and systemic regulation of breast cancer progression.

Science.gov (United States)

Castaño, Zafira; Tracy, Kristin; McAllister, Sandra S

2011-01-01

Breast cancer is the most common malignancy among women worldwide and is the most common cause of death for women between 35 and 50 years of age. Women with breast cancer are at risk of developing metastases for their entire lifetime and, despite local and systemic therapies, approximately 30% of breast cancer patients will relapse (Jemal et al., 2010). Nearly all breast cancer related deaths are due to metastatic disease, even though metastasis is considered to be an inefficient process. In some cases, tumor cells disseminate from primary sites at an early stage, but remain indolent for protracted periods of time before becoming overt, life-threatening tumors. Little is known about the mechanisms that cause these indolent tumors to grow into malignant disease. Because of this gap in our understanding, we are unable to predict which breast cancer patients are likely to experience disease relapse or develop metastases years after treatment of their primary tumor. A better understanding of the mechanisms and signals involved in the exit of tumor cells from dormancy would not only allow for more accurate selection of patients that would benefit from systemic therapy, but could also lead to the development of more targeted therapies to inhibit the signals that promote disease progression. In this review, we address the systemic, or "macroenvironmental", contribution to tumor initiation and progression and what is known about how a pro-tumorigenic systemic environment is established.

Progress in integrated energy-economy-environment model system development

International Nuclear Information System (INIS)

Yasukawa, Shigeru; Mankin, Shuichi; Sato, Osamu; Tadokoro, Yoshihiro; Nakano, Yasuyuki; Nagano, Takao

1987-11-01

The Integrated Energy-Economy-Environment Model System has been developed for providing analytical tools for the system analysis and technology assessments in the field of nuclear research and development. This model system consists of the following four model groups. The first model block installs 5 models and can serve to analyze and generate long-term scenarios on economy-energy-environment evolution. The second model block installs 2 models and can serve to analyze the structural transition phenomena in energy-economy-environment interactions. The third model block installs 2 models and can handle power reactor installation strategy problem and long-term fuel cycle analysis. The fourth model block installs 5 models and codes and can treats cost-benefit-risk analysis and assessments. This report describes mainly the progress and the outlines of application of the model system in these years after the first report on the research and development of the model system (JAERI-M 84 - 139). (author)

Placement of effective work-in-progress limits in route-specific unit-based pull systems

NARCIS (Netherlands)

Ziengs, N.; Riezebos, J.; Germs, R.

2012-01-01

Unit-based pull systems control the throughput time of orders in a production system by limiting the number of orders on the shop floor. In production systems where orders can follow different routings on the shop floor, route-specific pull systems that control the progress of orders on the shop

LANL environmental restoration site ranking system: System description. Final report

International Nuclear Information System (INIS)

Merkhofer, L.; Kann, A.; Voth, M.

1992-01-01

The basic structure of the LANL Environmental Restoration (ER) Site Ranking System and its use are described in this document. A related document, Instructions for Generating Inputs for the LANL ER Site Ranking System, contains detailed descriptions of the methods by which necessary inputs for the system will be generated. LANL has long recognized the need to provide a consistent basis for comparing the risks and other adverse consequences associated with the various waste problems at the Lab. The LANL ER Site Ranking System is being developed to help address this need. The specific purpose of the system is to help improve, defend, and explain prioritization decisions at the Potential Release Site (PRS) and Operable Unit (OU) level. The precise relationship of the Site Ranking System to the planning and overall budget processes is yet to be determined, as the system is still evolving. Generally speaking, the Site Ranking System will be used as a decision aid. That is, the system will be used to aid in the planning and budgetary decision-making process. It will never be used alone to make decisions. Like all models, the system can provide only a partial and approximate accounting of the factors important to budget and planning decisions. Decision makers at LANL will have to consider factors outside of the formal system when making final choices. Some of these other factors are regulatory requirements, DOE policy, and public concern. The main value of the site ranking system, therefore, is not the precise numbers it generates, but rather the general insights it provides

LANL environmental restoration site ranking system: System description. Final report

Energy Technology Data Exchange (ETDEWEB)

Merkhofer, L.; Kann, A.; Voth, M. [Applied Decision Analysis, Inc., Menlo Park, CA (United States)

1992-10-13

The basic structure of the LANL Environmental Restoration (ER) Site Ranking System and its use are described in this document. A related document, Instructions for Generating Inputs for the LANL ER Site Ranking System, contains detailed descriptions of the methods by which necessary inputs for the system will be generated. LANL has long recognized the need to provide a consistent basis for comparing the risks and other adverse consequences associated with the various waste problems at the Lab. The LANL ER Site Ranking System is being developed to help address this need. The specific purpose of the system is to help improve, defend, and explain prioritization decisions at the Potential Release Site (PRS) and Operable Unit (OU) level. The precise relationship of the Site Ranking System to the planning and overall budget processes is yet to be determined, as the system is still evolving. Generally speaking, the Site Ranking System will be used as a decision aid. That is, the system will be used to aid in the planning and budgetary decision-making process. It will never be used alone to make decisions. Like all models, the system can provide only a partial and approximate accounting of the factors important to budget and planning decisions. Decision makers at LANL will have to consider factors outside of the formal system when making final choices. Some of these other factors are regulatory requirements, DOE policy, and public concern. The main value of the site ranking system, therefore, is not the precise numbers it generates, but rather the general insights it provides.

Simulated coal gas MCFC power plant system verification. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-07-30

The objective of the main project is to identify the current developmental status of MCFC systems and address those technical issues that need to be resolved to move the technology from its current status to the demonstration stage in the shortest possible time. The specific objectives are separated into five major tasks as follows: Stack research; Power plant development; Test facilities development; Manufacturing facilities development; and Commercialization. This Final Report discusses the M-C power Corporation effort which is part of a general program for the development of commercial MCFC systems. This final report covers the entire subject of the Unocal 250-cell stack. Certain project activities have been funded by organizations other than DOE and are included in this report to provide a comprehensive overview of the work accomplished.

Recent Progress on Data-Based Optimization for Mineral Processing Plants

Directory of Open Access Journals (Sweden)

Jinliang Ding

2017-04-01

Full Text Available In the globalized market environment, increasingly significant economic and environmental factors within complex industrial plants impose importance on the optimization of global production indices; such optimization includes improvements in production efficiency, product quality, and yield, along with reductions of energy and resource usage. This paper briefly overviews recent progress in data-driven hybrid intelligence optimization methods and technologies in improving the performance of global production indices in mineral processing. First, we provide the problem description. Next, we summarize recent progress in data-based optimization for mineral processing plants. This optimization consists of four layers: optimization of the target values for monthly global production indices, optimization of the target values for daily global production indices, optimization of the target values for operational indices, and automation systems for unit processes. We briefly overview recent progress in each of the different layers. Finally, we point out opportunities for future works in data-based optimization for mineral processing plants.

Model validation studies of solar systems, Phase III. Final report

Energy Technology Data Exchange (ETDEWEB)

Lantz, L.J.; Winn, C.B.

1978-12-01

Results obtained from a validation study of the TRNSYS, SIMSHAC, and SOLCOST solar system simulation and design are presented. Also included are comparisons between the FCHART and SOLCOST solar system design programs and some changes that were made to the SOLCOST program. Finally, results obtained from the analysis of several solar radiation models are presented. Separate abstracts were prepared for ten papers.

Competence in the musculoskeletal system: assessing the progression of knowledge through an undergraduate medical course.

Science.gov (United States)

Basu, Subhashis; Roberts, Chris; Newble, David I; Snaith, Michael

2004-12-01

Professional bodies have expressed concerns that medical students lack appropriate knowledge in musculoskeletal medicine despite its high prevalence of use within the community. Changes in curriculum and teaching strategies may be contributing factors to this. There is little evidence to evaluate the degree to which these concerns are justified. To design and evaluate an assessment procedure that tests the progress of medical students in achieving a core level of knowledge in musculoskeletal medicine during the course. A stratified sample of 136 volunteer students from all 5 years of the medical course at Sheffield University. The progress test concept was adapted to provide a cross-sectional view of student knowledge gain during each year of the course. A test was devised which aimed to provide an assessment of competence set at the standard required of the newly qualified doctor in understanding basic and clinical sciences relevant to musculoskeletal medicine. The test was blueprinted against internal and external guidelines. It comprised 40 multiple-choice and extended matching questions administered by computer. Six musculoskeletal practitioners set the standard using a modified Angoff procedure. Test reliability was 0.6 (Cronbach's alpha). Mean scores of students increased from 41% in Year 1 to 84% by the final year. Data suggest that, from a baseline score in Year 1, there is a disparate experience of learning in Year 2 that evens out in Year 3, with knowledge progression becoming more consistent thereafter. All final year participants scored above the standard predicted by the Angoff procedure. This short computer-based test was a feasible method of estimating student knowledge acquisition in musculoskeletal medicine across the undergraduate curriculum. Tested students appear to have acquired a satisfactory knowledge base by the end of the course. Knowledge gain seemed relatively independent of specialty-specific clinical training. Proposals from specialty

Plasma exchange in progressive systemic sclerosis

Directory of Open Access Journals (Sweden)

Mohammad Bagher Owlia

2015-10-01

Full Text Available Systemic sclerosis (SSc is an autoimmune systemic disease of unknown etiology. Present treatment modalities have limited impact on clinical/ laboratory outcomes. For the first time in our center, we used plasma exchange (PEx in a rather young woman with recent onset but progressive SSc. She is a 39-year-old woman with a recent history of skin stiffness, Raynaud’s phenomenon, nail fold capillary changes and newly diagnosis of SSc presented to us due to worsening her clinical symptoms even after initiation of routine remedies such as low dose oral prednisolone, Ca-channel blockers, azathioprine and pentoxyfylline. After obtaining written consent, interdisciplinary discussion with experts in this field and agreement we started a series of plasma exchange with FFP replacement for her. A dramatic clinical response was observed in respect to Raynaud’s phenomenon, skin stiffness, tendon rub after three sessions of PEx. Her modified Rodnan skin score (MRSS dropped from 36 (before commencement of therapy to 28 in day 4 and 18 in day 20 after 15 sessions of PEx. In conclusion PEx could significantly modify the course of SSc as observed in our case study. Elimination of culprit immune mediators/cytokines/autoantibodies could be the possible mechanism of action of PEx. 

Homelessness Outcome Reporting Normative Framework: Systems-Level Evaluation of Progress in Ending Homelessness

Science.gov (United States)

Austen, Tyrone; Pauly, Bernie

2012-01-01

Homelessness is a serious and growing issue. Evaluations of systemic-level changes are needed to determine progress in reducing or ending homelessness. The report card methodology is one means of systems-level assessment. Rather than solely establishing an enumeration, homelessness report cards can capture pertinent information about structural…

Overview of Progress on the EU DEMO Reactor Magnet System Design

NARCIS (Netherlands)

Zani, L.; Bayer, C.; biancolini, M.E.; Bonifetto, R.; Nijhuis, Arend; Yagotintsev, K.

2016-01-01

The DEMO reactor is expected to be the first application of fusion for electricity generation in the near future. To this aim, conceptual design activities are progressing in Europe (EU) under the lead of the EUROfusion Consortium in order to drive on the development of the major tokamak systems. In

The spectrum of progressive derecho formation environments

Science.gov (United States)

Guastini, Corey T.

Progressive derechos are severe mesoscale convective systems that often form east of the Rocky Mountains during the warm season (May--August) and cause, by definition, straight-line wind damage along paths upwards of 400 km long. This study develops a subjective, seven-category classification scheme that spans the spectrum of progressive derecho formation environments from those dominated by robust upper-level ridges to those characterized by vigorous upper-level troughs. A climatology of 256 progressive derecho events is created for 1996--2013 and is categorized according to the developed classification scheme. Derecho initiation-relative composites are constructed for each of the seven groups using 0.5° Climate Forecast System Reanalysis data to document the environmental characteristics unique to each group as well as those shared among them. Finally, two in-depth case studies and five cursory case studies provide examples of the seven categories and reveal important nuances in mesoscale dynamic and thermodynamic structure inherent to all derecho cases. Results of the climatology show progressive derecho activity increases from 1 May through 1 July before decreasing again through the end of August and follows a northward trend in latitude from 1 May through 1 August before shifting slightly southward through the end of the warm season. Upslope flow in the vicinity of the Rocky Mountains initiates 28 percent of progressive derechos, upper-level troughs initiate 20 percent, 47 percent form in benign synoptic environments, and 5 percent are unclassifiable. Composite results show all progressive derecho initiation environments are marked by a long axis of instability caused by the overlap of high atmospheric moisture content and steep midlevel lapse rates, but the relative positions and strengths of upper-level troughs and ridges are crucial in determining how the instability axis develops and what its orientation in space will be. Case studies reveal instability

Ultraviolet irradiation of nucleic acids and related compounds. Final progress report

International Nuclear Information System (INIS)

Wang, S.Y.

1976-01-01

Progress is reported on the following research projects: photohydration of pyrimidine derivatives; thymine dimerization; uv-induced formation of pyrimidinyl radicals; formation of a coupled product by irradiation of 5-bromouracil derivatives; studies on pyrimidine adducts; molecular aggregates-puddle formation hypothesis of pyrimidine photodimerization; and topochemical studies of structures of dimers and of crystalline arrangements

Laser surveillance system (LASSY)

International Nuclear Information System (INIS)

Boeck, H.; Hammer, J.

1988-01-01

The development progress during the reporting period 1988 of the laser surveillance system of spent fuel pools is summarized. The present engineered system comes close to a final version for field application as all technical questions have been solved in 1988. 14 figs., 1 tab. (Author)

48 CFR 32.503-3 - Initiation of progress payments and review of accounting system.

Science.gov (United States)

2010-10-01

... payments and review of accounting system. 32.503-3 Section 32.503-3 Federal Acquisition Regulations System... on Costs 32.503-3 Initiation of progress payments and review of accounting system. (a) For... review (within the last 12 months) to be (1) reliable, competent, and capable of satisfactory performance...

Progress and Challenges in Developing Aptamer-Functionalized Targeted Drug Delivery Systems

Directory of Open Access Journals (Sweden)

Feng Jiang

2015-10-01

Full Text Available Aptamers, which can be screened via systematic evolution of ligands by exponential enrichment (SELEX, are superior ligands for molecular recognition due to their high selectivity and affinity. The interest in the use of aptamers as ligands for targeted drug delivery has been increasing due to their unique advantages. Based on their different compositions and preparation methods, aptamer-functionalized targeted drug delivery systems can be divided into two main categories: aptamer-small molecule conjugated systems and aptamer-nanomaterial conjugated systems. In this review, we not only summarize recent progress in aptamer selection and the application of aptamers in these targeted drug delivery systems but also discuss the advantages, challenges and new perspectives associated with these delivery systems.

Progressive reduction of the thermal wall system by modal analysis

Energy Technology Data Exchange (ETDEWEB)

Mokhtari, A.; Meslem, A.; Bounif, A.; Kadi, L. [Universite des Sciences et de la Technologie, Oran (Algeria)

1993-12-31

A reduction method of thermal systems called ``progress`` using the modal Analysis is presented. It allows to do, at each time of simulation, a synthesis information in the system evolution. Consequently, the limited number of descriptive and significant parameters (proper modes), can produce some extremely useful indication about dynamic evolution. However this method can eliminate proper modes of which the energetic contribution will be neglected or amortized. Some examples were studied, showing the efficiency of this method by reducing the computing time, as well as, having high precision on predicted dynamic response over time of simulation. (Authors). 4 refs., 4 figs.

Recent Progresses in Incorporating Human Land-Water Management into Global Land Surface Models Toward Their Integration into Earth System Models

Science.gov (United States)

Pokhrel, Yadu N.; Hanasaki, Naota; Wada, Yoshihide; Kim, Hyungjun

2016-01-01

The global water cycle has been profoundly affected by human land-water management. As the changes in the water cycle on land can affect the functioning of a wide range of biophysical and biogeochemical processes of the Earth system, it is essential to represent human land-water management in Earth system models (ESMs). During the recent past, noteworthy progress has been made in large-scale modeling of human impacts on the water cycle but sufficient advancements have not yet been made in integrating the newly developed schemes into ESMs. This study reviews the progresses made in incorporating human factors in large-scale hydrological models and their integration into ESMs. The study focuses primarily on the recent advancements and existing challenges in incorporating human impacts in global land surface models (LSMs) as a way forward to the development of ESMs with humans as integral components, but a brief review of global hydrological models (GHMs) is also provided. The study begins with the general overview of human impacts on the water cycle. Then, the algorithms currently employed to represent irrigation, reservoir operation, and groundwater pumping are discussed. Next, methodological deficiencies in current modeling approaches and existing challenges are identified. Furthermore, light is shed on the sources of uncertainties associated with model parameterizations, grid resolution, and datasets used for forcing and validation. Finally, representing human land-water management in LSMs is highlighted as an important research direction toward developing integrated models using ESM frameworks for the holistic study of human-water interactions within the Earths system.

Radiation chemistry of hydrocarbon and alkyl halide systems. Progress report, August 1, 1982-July 31, 1983

International Nuclear Information System (INIS)

Hanrahan, R.J.

1983-01-01

Experimental work was in progress during the past year on three systems: investigation of gas phase OH radical reactions using the pulse radiolysis method; studies of the radiolytic oxidation of propane; and an investigation of photochemistry and mass spectrometry of CF 3 I-CH 3 I mixtures. In addition, data analysis and interpretation of previously obtained results on H 2 /CO systems was under way. Progress made in these areas is described

Progress towards extreme attitude testing with Magnetic Suspension and Balance Systems

Science.gov (United States)

Britcher, Colin P.; Parker, David H.

1988-01-01

Progress is reported in a research effort aimed towards demonstration of the feasibility of suspension and aerodynamic testing of models at high angles of attack in wind tunnel Magnetic Suspension and Balance Systems. Extensive modifications, described in this paper, have been made to the Southampton University suspension system in order to facilitate this work. They include revision of electromagnet configuration, installation of all-new position sensors and expansion of control system programs. An angle of attack range of 0 to 90 deg is expected for axisymmetric models. To date, suspension up to 80 deg angle of attack has been achieved.

Recent progress and development of building vibration control systems in Japan

International Nuclear Information System (INIS)

Izumi, Masanori

1989-01-01

Japan is on a seismically active zone. The people are frequently shaken, and there is good reason to develop vibration control systems. Ministries and major construction companies have contributed to the progress of the technology. An example is the Fast Breeder Reactor (FBR) Research project, which may be equipped with a base-isolation system. Rubber bearings will be standardized and base-isolated buildings will be designed and constructed easily on good ground in the near future. But one needs time to realize a building with an active control system, which is effective in potentially destructive earthquakes

Insulation Progress since the Mid-1950s

Science.gov (United States)

Timmerhaus, K. D.

Storage vessel and cryostat design for modern cryogenic systems has become rather routine as the result of the wide use of and application of cryogenic fluids. Such vessels for these fluids range in size from 1 L flasks used in the laboratory for liquid nitrogen to the more than 200,000 m3 double-walled tanks used for temporary storage of liquefied natural gas before being transported overseas to their final destination. These storage vessels for cryogenic fluids range in type from low-performance containers insulated with rigid foam or fibrous insulation to high-performance containers insulated with evacuated multilayer insulations. The overriding factors in the type of container selected normally are of economics and safety. This paper will consider various insulation concepts used in such cryogenic storage systems and will review the progress that has been made over the past 50 years in these insulation systems.

Building Construction Progress Monitoring Using Unmanned Aerial System (uas), Low-Cost Photogrammetry, and Geographic Information System (gis)

Science.gov (United States)

Bognot, J. R.; Candido, C. G.; Blanco, A. C.; Montelibano, J. R. Y.

2018-05-01

Monitoring the progress of building's construction is critical in construction management. However, measuring the building construction's progress are still manual, time consuming, error prone, and impose tedious process of analysis leading to delays, additional costings and effort. The main goal of this research is to develop a methodology for building construction progress monitoring based on 3D as-built model of the building from unmanned aerial system (UAS) images, 4D as-planned model (with construction schedule integrated) and, GIS analysis. Monitoring was done by capturing videos of the building with a camera-equipped UAS. Still images were extracted, filtered, bundle-adjusted, and 3D as-built model was generated using open source photogrammetric software. The as-planned model was generated from digitized CAD drawings using GIS. The 3D as-built model was aligned with the 4D as-planned model of building formed from extrusion of building elements, and integration of the construction's planned schedule. The construction progress is visualized via color-coding the building elements in the 3D model. The developed methodology was conducted and applied from the data obtained from an actual construction site. Accuracy in detecting `built' or `not built' building elements ranges from 82-84 % and precision of 50-72 %. Quantified progress in terms of the number of building elements are 21.31% (November 2016), 26.84 % (January 2017) and 44.19 % (March 2017). The results can be used as an input for progress monitoring performance of construction projects and improving related decision-making process.

COE-INES report on research and education activities. Final report

International Nuclear Information System (INIS)

2008-03-01

Research and education activities on innovative nuclear energy systems to solve safety, radioactive waste and proliferation problems simultaneously, were summarized as a final report of COE-INES program. CANDLE (Constant Axial shape of Neutron flux, nuclide densities and power shape During Life of Energy producing reactor), lead-bismuth cooled fast reactors, small long-life reactors and water-cooled thorium breeding reactors were studies as innovative nuclear reactors. Experimental study of hydrogen system with carbon dioxide zero emission was progressed. Basic research on micro/nano-scale separation/transmutation of actinide nuclides and long-life fission products was conducted. Research on nuclear energy and social involvement was also conducted. (J.P.N.)

Method and system for progressive mesh storage and reconstruction using wavelet-encoded height fields

Science.gov (United States)

Baxes, Gregory A. (Inventor); Linger, Timothy C. (Inventor)

2011-01-01

Systems and methods are provided for progressive mesh storage and reconstruction using wavelet-encoded height fields. A method for progressive mesh storage includes reading raster height field data, and processing the raster height field data with a discrete wavelet transform to generate wavelet-encoded height fields. In another embodiment, a method for progressive mesh storage includes reading texture map data, and processing the texture map data with a discrete wavelet transform to generate wavelet-encoded texture map fields. A method for reconstructing a progressive mesh from wavelet-encoded height field data includes determining terrain blocks, and a level of detail required for each terrain block, based upon a viewpoint. Triangle strip constructs are generated from vertices of the terrain blocks, and an image is rendered utilizing the triangle strip constructs. Software products that implement these methods are provided.

Prediction of Curve Progression in Idiopathic Scoliosis: Validation of the Sanders Skeletal Maturity Staging System.

Science.gov (United States)

Sitoula, Prakash; Verma, Kushagra; Holmes, Laurens; Gabos, Peter G; Sanders, James O; Yorgova, Petya; Neiss, Geraldine; Rogers, Kenneth; Shah, Suken A

2015-07-01

Retrospective case series. This study aimed to validate the Sanders Skeletal Maturity Staging System and to assess its correlation to curve progression in idiopathic scoliosis. The Sanders Skeletal Maturity Staging System has been used to predict curve progression in idiopathic scoliosis. This study intended to validate that initial study with a larger sample size. We retrospectively reviewed 1100 consecutive patients with idiopathic scoliosis between 2005 and 2011. Girls aged 8 to 14 years (skeletal age and scoliosis curve magnitude were followed to skeletal maturity (Risser stage 5 or fully capped Risser stage 4), curve progression to 50° or greater, or spinal fusion. Patients with nonidiopathic curves were excluded. There were 161 patients: 131 girls (12.3 ± 1.2 yr) and 30 boys (13.9 ± 1.1 yr). The distribution of patients within Sanders stage (SS) 1 through 7 was 7, 28, 41, 45, 7, 31, and 2 patients, respectively; modified Lenke curve types 1 to 6 were 26, 12, 63, 5, 38, and 17 patients, respectively. All patients in SS2 with initial Cobb angles of 25° or greater progressed, and patients in SS1 and SS3 with initial Cobb angles of 35° or greater progressed. Similarly, all patients with initial Cobb angles of 40° or greater progressed except those in SS7. Conversely, none of the patients with initial Cobb angles of 15° or less or those in SS5, SS6, and SS7 with initial Cobb angles of 30° or less progressed. Predictive progression of 67%, 50%, 43%, 27%, and 60% was observed for subgroups SS1/30°, SS2/20°, SS3/30°, SS4/30°, and SS6/35° respectively. This larger cohort shows a strong predictive correlation between SS and initial Cobb angle for probability of curve progression in idiopathic scoliosis. 3.

Hot Gas Conditioning: Recent Progress with Larger-Scale Biomass Gasification Systems; Update and Summary of Recent Progress

Energy Technology Data Exchange (ETDEWEB)

Stevens, D. J.

2001-09-01

As a result of environmental and policy considerations, there is increasing interest in using renewable biomass resources as feedstock for power, fuels, and chemicals and hydrogen. Biomass gasification is seen as an important technology component for expanding the use of biomass. Advanced biomass gasification systems provide clean products that can be used as fuel or synthesis gases in a variety of environmentally friendly processes. Advanced end-use technologies such as gas turbines or synthesis gas systems require high quality gases with narrowly defined specifications. Other systems such as boilers may also have fuel quality requirements, but they will be substantially less demanding. The gas product from biomass gasifiers contains quantities of particulates, tars, and other constituents that may exceed these specified limits. As a result, gas cleaning and conditioning will be required in most systems. Over the past decade, significant research and development activities have been conducted on the topic of gas cleanup and conditioning. This report provides an update of efforts related to large-scale biomass gasification systems and summarizes recent progress. Remaining research and development issues are also summarized.

Development of indigenous irradiator - current progress and challenges

International Nuclear Information System (INIS)

Anwar A Rahman; Mohd Arif Hamzah; Muhd Nor Atan; Aznor Hassan; Fadil Ismail; Julia A Karim; Rosli Darmawan

2009-01-01

The development of indigenous irradiator is one of Prototype Development Center main project to support Nuclear Malaysia services. Three (3) projects have been identified and currently the status is in final stage of design. There are some issues and challenges encountered, which delayed the project progress. The paper will discuss the current progress of development and challenges faced in designing the irradiator. (Author)

Final disposal of radioactive wastes

Energy Technology Data Exchange (ETDEWEB)

Kroebel, R [Kernforschungszentrum Karlsruhe G.m.b.H. (Germany, F.R.). Projekt Wiederaufarbeitung und Abfallbehandlung; Krause, H [Kernforschungszentrum Karlsruhe G.m.b.H. (Germany, F.R.). Abt. zur Behandlung Radioaktiver Abfaelle

1978-08-01

This paper discusses the final disposal possibilities for radioactive wastes in the Federal Republic of Germany and the related questions of waste conditioning, storage methods and safety. The programs in progress in neighbouring CEC countries and in the USA are also mentioned briefly. The autors conclude that the existing final disposal possibilities are sufficiently well known and safe, but that they could be improved still further by future development work. The residual hazard potential of radioactive wastes from fuel reprocessing after about 1000 years of storage is lower that of known inorganic core deposits.

Progress and challenges to the global waste management system.

Science.gov (United States)

Singh, Jagdeep; Laurenti, Rafael; Sinha, Rajib; Frostell, Björn

2014-09-01

Rapid economic growth, urbanization and increasing population have caused (materially intensive) resource consumption to increase, and consequently the release of large amounts of waste to the environment. From a global perspective, current waste and resource management lacks a holistic approach covering the whole chain of product design, raw material extraction, production, consumption, recycling and waste management. In this article, progress and different sustainability challenges facing the global waste management system are presented and discussed. The study leads to the conclusion that the current, rather isolated efforts, in different systems for waste management, waste reduction and resource management are indeed not sufficient in a long term sustainability perspective. In the future, to manage resources and wastes sustainably, waste management requires a more systems-oriented approach that addresses the root causes for the problems. A specific issue to address is the development of improved feedback information (statistics) on how waste generation is linked to consumption. © The Author(s) 2014.

China's health care system reform: Progress and prospects.

Science.gov (United States)

Li, Ling; Fu, Hongqiao

2017-07-01

This paper discusses the progress and prospects of China's complex health care reform beginning in 2009. The Chinese government's undertaking of systemic reform has achieved laudable achievements, including the expansion of social health insurance, the reform of public hospitals, and the strengthening of primary care. An innovative policy tool in China, policy experimentation under hierarchy, played an important role in facilitating these achievements. However, China still faces gaps and challenges in creating a single payer system, restructuring the public hospitals, and establishing an integrated delivery system. Recently, China issued the 13th 5-year plan for medical reform, setting forth the goals, policy priorities, and strategies for health reform in the following 5 years. Moreover, the Chinese government announced the "Healthy China 2030" blueprint in October 2016, which has the goals of providing universal health security for all citizens by 2030. By examining these policy priorities against the existing gaps and challenges, we conclude that China's health care reform is heading in the right direction. To effectively implement these policies, we recommend that China should take advantage of policy experimentation to mobilize bottom-up initiatives and encourage innovations. Copyright © 2017 John Wiley & Sons, Ltd.

Plutonium Protection System (PPS). Volume 2. Hardware description. Final report

International Nuclear Information System (INIS)

Miyoshi, D.S.

1979-05-01

The Plutonium Protection System (PPS) is an integrated safeguards system developed by Sandia Laboratories for the Department of Energy, Office of Safeguards and Security. The system is designed to demonstrate and test concepts for the improved safeguarding of plutonium. Volume 2 of the PPS final report describes the hardware elements of the system. The major areas containing hardware elements are the vault, where plutonium is stored, the packaging room, where plutonium is packaged into Container Modules, the Security Operations Center, which controls movement of personnel, the Material Accountability Center, which maintains the system data base, and the Material Operations Center, which monitors the operating procedures in the system. References are made to documents in which details of the hardware items can be found

Final Progress Report for Collaborative Research: Aging of Black Carbon during Atmospheric Transport: Understanding Results from the DOE’s 2010 CARES and 2012 ClearfLo Campaigns

Energy Technology Data Exchange (ETDEWEB)

Mazzoleni, Claudio [Michigan Technological Univ., Houghton, MI (United States); Subramanian, R. [Carnegie Mellon Univ., Pittsburgh, PA (United States)

2016-08-31

Over the course of this project, we have analyzed data and samples from the Carbonaceous Aerosol and Radiative Effects Study (CARES) and the Clear air for London (ClearfLo) campaign, as well as conducted or participated in laboratory experiments designed to better understand black carbon mixing state and climate-relevant properties. The laboratory campaigns took place at the Pacific Northwest National Laboratory and Carnegie Mellon University to study various climate-relevant aerosol properties of different sources of soot mixing with secondary organic aerosol precursors. Results from some of these activities were summarized in the previous progress report. This final report presents the manuscripts that have been published (many in the period since the last progress report), lists presentations at different conferences based on grant-related activities, and presents some results that are likely to be submitted for publication in the near future.

131I albumin of patients carrying progressive systemic sclerosis study

International Nuclear Information System (INIS)

Cossermelli, W.; Carvalho, N.; Papaleo Netto, M.

1974-01-01

131 I albumin metabolic changes were studied in 14 female patients with progressive systemic sclerosis. A statistical study of the gathered data disclosed increased distribution and turnover half-life and diminished turnover rate of radioactive substance. Since T/2 of turnover and turnover rate are the result produced by the albumin synthesis and degradation, they are probably lowered during active disease causing hypoalbuminemia. The aminoacids also are probably absorbed by other protein like the gammaglobuline synthesis [pt

Progress report on a fully automatic Gas Tungsten Arc Welding (GTAW) system development

Energy Technology Data Exchange (ETDEWEB)

Daumeyer, G.J. III

1994-12-01

A plan to develop a fully automatic gas tungsten arc welding (GTAW) system that will utilize a vision-sensing computer (which will provide in-process feedback control) is presently in work. Evaluations of different technological aspects and system design requirements continue. This report summaries major activities in the plan`s successful progress. The technological feasibility of producing the fully automated GTAW system has been proven. The goal of this process development project is to provide a production-ready system within the shortest reasonable time frame.

FINAL Progress Report DOE Grant DE-FG02-04ER15587

Energy Technology Data Exchange (ETDEWEB)

Mullins, Charles Buddie [Univ. of Texas, Austin, TX (United States)

2016-11-03

Catalysis Program - Viviane Schwartz Program Manager This Final Report discusses several archival journal articles that have been published that present and discuss the results that were discovered through this DOE grant.

1984-85 ISN progress report

International Nuclear Information System (INIS)

1985-01-01

This progress report ISN 1984-1985 deals with the following subjects: nuclear physics theory, peripheral and intermediate energy physics, characteristics of reaction mechanisms in heavy ion collisions, nuclear structure, fundamental interactions, experimental methods and new instrumentation, some interdisciplinary research activities and technical activities, the SARA cyclotron and finally, technology transfer and valorisation [fr

TLR5 signaling, commensal microbiota and systemic tumor promoting inflammation: the three parcae of malignant progression.

Science.gov (United States)

Rutkowski, Melanie R; Conejo-Garcia, Jose R

2015-08-01

We have reported that TLR5-mediated recognition of commensal microbiota modulates systemic tumor-promoting inflammation and malignant progression of tumors at distal locations. Approximately 7-10% of the general population harbors a deleterious single nucleotide polymorphism in TLR5, implicating a novel role for genetic variation during the initiation and progression of cancer.

Design, Fabrication, and Certification of Advanced Modular PV Power Systems Final Technical Progress Report

International Nuclear Information System (INIS)

Minyard, G.

1998-01-01

This report describes the overall accomplishments and benefits of Solar Electric Specialties Co. (SES) under this Photovoltaic Manufacturing Technology (PVMaT) subcontract. SES addressed design issues related to their modular autonomous PV power supply (MAPPS) and a mobile photogenset. MAPPS investigations included gel-cell batteries mounted horizontally; redisgn of the SES power supply; modified battery enclosure for increased safety and reduced cost; programmable, interactive battery charge controllers; and UL and FM listings. The photogenset systems incorporate generators, battery storage, and PV panels for a mobile power supply. The unit includes automatic oil-change systems for the propane generators, collapsible array mounts for the PV enclosure, and internal stowage of the arrays. Standardizing the products resulted in product lines of MAPPS and Photogensets that can be produced more economically and with shorter lead times, while increasing product quality and reliability. Product assembly and quality control have also been improved and streamlined with the development of standardized assembly processes and QC testing procedures. SES offers the UL-listed MAPPS at about the same price as its previous non-standardized, unlisted products

Advanced turbine systems program. Final report, August 3, 1993--August 31, 1996

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-12-31

Six tasks were approved under the Advanced Turbine Systems (ATS) extension program. The six tasks include the following: Task 5.0 -- Market Study. The objective of the market study task is to focus on distributed generation prospects for an industrial ATS, using the Allison ATS family as the primary gas turbine systems. Task 6.0 -- Gas Fired Advanced Turbine System (GFATS) Definition and Analysis. Task 8.01 -- Castcool{reg_sign} Blades Fabrication Process Development. Task 8.04 -- ATS Low Emission Combustion System. Task 8.07 -- Ceramic Vane Design and Evaluation. Task 9.0 -- Program Management. Each of these tasks is described, progress is discussed, and results are given.

A conceptual design of Final Focus Systems for linear colliders

International Nuclear Information System (INIS)

Brown, K.L.

1987-06-01

Linear colliders are a relatively recent development in the evolution of particle accelerators. This report discusses some of the approaches that have been considered for the design of Final Focus Systems to demagnify the beam exiting from a linac to the small size suitable for collisions at the interaction point. The system receiving the most attention is the one adopted for the SLAC Linear Collider. However, the theory and optical techniques discussed should be applicable to the design efforts for future machines

Hydrogen storage - are we making progress?

International Nuclear Information System (INIS)

Blair, L.; Milliken, J.; Satyapal, S.

2004-01-01

'Full text:' The efficient storage of hydrogen in compact, lightweight systems that allow greater than 300-mile range has been identified as one of the major technical challenges facing the practical commercialization of fuel cell power systems for light-duty vehicles. Following the hydrogen vision announced by President Bush in his 2003 State of the Union address, the U.S. Department of Energy issued a Grand Challenge, soliciting ideas from universities, national laboratories, and industry. DOE's National Hydrogen Storage Project, an aggressive and innovative research program focused on materials R and D, will be launched in Fiscal Year 2005. An intensive effort is also underway in the private sector, both in the U.S. and abroad, to meet the challenging on-board hydrogen storage requirements. A historical perspective of hydrogen storage research and development will be provided and the current DOE technical targets for hydrogen storage systems will be discussed. The state-of-the-art in hydrogen storage will be summarized and recent progress assessed. Finally future research directions and areas of technical emphasis will be described. (author)

Progress in triboluminescence-based smart optical sensor system

International Nuclear Information System (INIS)

Olawale, David O.; Dickens, Tarik; Sullivan, William G.; Okoli, Okenwa I.; Sobanjo, John O.; Wang, Ben

2011-01-01

Extensive research work has been done in recent times to apply the triboluminescence (TL) phenomenon for damage detection in engineering structures. Of particular note are the various attempts to apply it in the detection of impact damages in composites and aerospace structures. This is because TL-based sensor systems have a great potential for wireless, in-situ and distributed (WID) structural health monitoring when fully developed. This review article highlights development and the current state-of-the-art in the application of TL-based sensor systems. The underlying mechanisms believed to be responsible for triboluminescence, particularly in zinc sulfide manganese, a highly triboluminescent material, are discussed. The challenges militating against the full exploitation and field application of TL sensor systems are also identified. Finally, viable solutions and approaches to address these challenges are enumerated. - Highlights: → The underlying mechanisms believed to be responsible for triboluminescence. → State-of-the-art in the development and application of TL-based sensor systems. → The challenges militating against the full exploitation and field application of TL sensor systems are identified. → Viable solutions and approaches to address these challenges are enumerated.

Technical progress report

International Nuclear Information System (INIS)

1996-01-01

This report summarizes experimental and theoretical work in basic nuclear physics carried out between October 1, 1995, the closing of our last Progress Report, and September 30, 1996 at the Nuclear Physics Laboratory of the University of Colorado, Boulder, under contracts DE-FG03-93ER-40774 and DE-FG03-95ER-40913 with the United States Department of Energy. The experimental contract supports broadly-based experimental research in intermediate energy nuclear physics. This report includes results from studies of Elementary Systems involving the study of the structure of the nucleon via polarized high-energy positron scattering (the HERMES experiment) and lower energy pion scattering from both polarized and unpolarized nucleon targets. Results from pion- and kaon-induced reactions in a variety of nuclear systems are reported under the section heading Meson Reactions; the impact of these and other results on understanding the nucleus is presented in the Nuclear Structure section. In addition, new results from scattering of high-energy electrons (from CEBAF/TJNAF) and pions (from KEK) from a broad range of nuclei are reported in the section on Incoherent Reactions. Finally, the development and performance of detectors produced by the laboratory are described in the section titled Instrumentation

Esophageal function scintigraphy as parameter for organ involvement of progressive systemic scleroderma

International Nuclear Information System (INIS)

Leisner, B.; Koenig, G.; Hundegger, K.; Luderschmidt, C.

1986-01-01

Involvement of internal organs such as lungs, heart and kidneys, is a life-threatening complication in progressive systemic scleroderma (PSS). However, the earliest and the most frequent internal manifestation of PSS is that of esophageal dysfunction. This study was undertaken to determine whether the new, sensitive and noninvasive esphageal function scintigraphy (EFS) enables us to identify patients likely to develop pulmonary interstitial fibrosis. 131 patients with PSS of different clinical types and courses underwent EFS. The esophageal clearance of a sup(99m)Tc-tagged 15 ml water bolus was measured. In normals, 91 +- 4.8% of the maximal rate were cleared from the ROI comprising the whole esophagus 10 sec after T max was reached. For comparison, chest X-rays and pulmonary function data were used. In the presence of interstitial lung disease EFS gave normal results in four patients only (sensitivity, 89%). All cases with either severely impaired lung function or signs of fibrosis on X-ray films showed esophageal clearance values below 40%. Moreover, esophageal motility disorders were seen in 32 among 43 patients with normal lung function. There was a correlationi between the stage and progression (reflected by unspecific signs of inflammation) and the incidence and severity of both lung function impairment and esophageal dysfunction. In conclusion, functional scintigraphy proved to be a very sensitive diagnostic procedure in the screening for internal manifestations of progressive systemic scleroderma. (Author)

Measurement of observables in the pion-nucleon system and investigation of charge symmetry in 3H and 3He: Progress report, March 1, 1986-February 28, 1987

International Nuclear Information System (INIS)

Sadler, M.E.

1987-03-01

This report describes the progress made in the past year in the pion scattering programs in which Abilene Christian University is collaborating. The measurements include (1) a complete set of observables in the pion-nucleon system in the momentum interval 400 to 700 MeV/e, (2) differential cross sections at low energy for pion-nucleon charge exchange, and (3) elastic and inelastic scattering of π +- on 3 H and 3 He. Highlights of the progress in 1986 to 87 include (1) first measurement of the spin rotation parameters A and R for π +- p → π +- p scattering at 427 to 657 MeV/e, for which the principal investigator received support from Associated Western Universities (AWU) and ACU for sabbatical leave in Los Alamos, (2) final publication of the data for the differential cross sections and analyzing powers for π +- p elastic scattering at 378 to 687 MeV/c, (3) final publication of forward-angle differential cross sections for π - p → π 0 n at 101 to 147 MeV/c, and (4) continued development of analysis capabilities on the ACU VAX-11/785, including full implementation of the LAMPF Q system MAPPER and DISSPLA graphics software. TEDI and TEX word processing and the associated hardware to utilize the software. The experiments are conducted at the Clinton P. Anderson Meson Physics Facility at Los Alamos (LAMPF). The experiments are performed in collaboration with UCLA, George Washington University, LAMPF Groups MP-4, MP-10 and MP-13, and Catholic University. 37 refs., 13 figs., 1 tab

Los Angeles-Gateway Freight Advanced Traveler Information System : final system design and architecture for FRATIS prototype.

Science.gov (United States)

2013-05-01

This Final Architecture and Design report has been prepared to describe the structure and design of all the system : components for the LA-Gateway FRATIS Demonstration Project. More specifically, this document provides: : Detailed descriptions of...

Physiologic abnormalities of cardiac function in progressive systemic sclerosis with diffuse scleroderma

International Nuclear Information System (INIS)

Follansbee, W.P.; Curtiss, E.I.; Medsger, T.A. Jr.; Steen, V.D.; Uretsky, B.F.; Owens, G.R.; Rodnan, G.P.

1984-01-01

To investigate cardiopulmonary function in progressive systemic sclerosis with diffuse scleroderma, we studied 26 patients with maximal exercise and redistribution thallium scans, rest and exercise radionuclide ventriculography, pulmonary-function testing, and chest roentgenography. Although only 6 patients had clinical evidence of cardiac involvement, 20 had abnormal thallium scans, including 10 with reversible exercise-induced defects and 18 with fixed defects (8 had both). Seven of the 10 patients who had exercise-induced defects and underwent cardiac catheterization had normal coronary angiograms. Mean resting left ventricular ejection fraction and mean resting right ventricular ejection fraction were lower in patients with post-exercise left ventricular thallium defect scores above the median (59 +/- 13 per cent vs. 69 +/- 6 per cent, and 36 +/- 12 per cent vs. 47 +/- 7 per cent, respectively). The authors conclude that in progressive systemic sclerosis with diffuse scleroderma, abnormalities of myocardial perfusion are common and appear to be due to a disturbance of the myocardial microcirculation. Both right and left ventricular dysfunction appear to be related to this circulatory disturbance, suggesting ischemically mediated injury

Progress in real-time feedback control systems in RFX

Energy Technology Data Exchange (ETDEWEB)

Barana, O.; Luchetta, A. E-mail: adriano.luchetta@igi.cnr.it; Manduchi, G.; Taliercio, C

2004-06-01

Major modifications of the RFX load assembly and power supplies are in progress to allow extensive active control schemes, such as equilibrium and plasma position control and innovative control of the MHD modes. The digital control system is implemented in VME64 using a distributed architecture. The use of a 'stable' operating system that is likely to survive some generations of processors can help coping with evolution of technology. PowerPC and Pentium processors were thus considered as candidates and tested and the first one has been selected due to the better performance in floating point computation. Wind River VxWorks has been chosen as real-time operating system. 100 Mbit switched Ethernet has been evaluated for real-time communication by using the user datagram protocol (UDP). Measurements have been executed on a prototype system to assess data transfer latency, jitter and reliability and the results confirm that the solution is suitable for the application. The paper describes in detail the reasons for the choice in the hardware components. Results from several tests comparing the performance of different solutions are also provided.

A Dynamic Alignment System for the Final Focus Test Beam

International Nuclear Information System (INIS)

Ruland, R.E.; Bressler, V.E.; Fischer, G.; Plouffe, D.; SLAC

2005-01-01

The Final Focus Test Beam (FFTB) was conceived as a technological stepping stone on the way to the next linear collider. Nowhere is this more evident than with the alignment subsystems. Alignment tolerances for components prior to beam turn are almost an order of magnitude smaller than for previous projects at SLAC. Position monitoring systems which operate independent of the beam are employed to monitor motions of the components locally and globally with unprecedented precision. An overview of the FFTB alignment system is presented herein

Activity Progress report 1982-1985

International Nuclear Information System (INIS)

1986-01-01

This reports gives a summary of all activities of the Elementary Particle Physics Department at Saclay between the beginning of 1982 and the end of 1985. The experiments in progress or in preparation are presented by subject. The main technical studies and achievements are also described. Finally lists of publications and information concerning Department organization are given [fr

Progress of the AVNG System - Attribute Verification System with Information Barriers for Mass Isotopics Measurements

International Nuclear Information System (INIS)

Budnikov, D.; Bulatov, M.; Jarikhine, I.; Lebedev, B.; Livke, A.; Modenov, A.; Morkin, A.; Razinkov, S.; Tsaregorodtsev, D.; Vlokh, A.; Yakovleva, S.; Elmont, T.H.; Langner, D.C.; MacArthur, D.W.; Mayo, D.R.; Smith, M.K.; Luke, S.J.

2005-01-01

An attribute verification system (AVNG) with information barriers for mass and isotopics measurements has been designed and its fabrication is nearly completed. The AVNG is being built by scientists at the Russian Federal Nuclear Center-VNIIEF, with support of Los Alamos National Laboratory (LANL) and Lawrence Livermore National Laboratory (LLNL). Such a system could be used to verify the presence of several unclassified attributes of classified material with no classified information release. The system is comprised of a neutron multiplicity counter and gamma-spectrometry system based on a high purity germanium gamma detector (nominal relative efficiency @ 1332 keV 50%) and digital gamma-ray spectrometer DSPEC PLUS . The neutron multiplicity counter is a three ring counter with 164 3 He tubes. The system was designed to measure prototype containers 491 mm in diameter and 503 mm high. This paper provides a brief history of the project and documents the progress of this effort with drawings and photographs.

[RESEARCH PROGRESS OF PERIPHERAL NERVE SURGERY ASSISTED BY Da Vinci ROBOTIC SYSTEM].

Science.gov (United States)

Shen, Jie; Song, Diyu; Wang, Xiaoyu; Wang, Changjiang; Zhang, Shuming

2016-02-01

To summarize the research progress of peripheral nerve surgery assisted by Da Vinci robotic system. The recent domestic and international articles about peripheral nerve surgery assisted by Da Vinci robotic system were reviewed and summarized. Compared with conventional microsurgery, peripheral nerve surgery assisted by Da Vinci robotic system has distinctive advantages, such as elimination of physiological tremors and three-dimensional high-resolution vision. It is possible to perform robot assisted limb nerve surgery using either the traditional brachial plexus approach or the mini-invasive approach. The development of Da Vinci robotic system has revealed new perspectives in peripheral nerve surgery. But it has still been at the initial stage, more basic and clinical researches are still needed.

Gastric emptying abnormalities in progressive systemic sclerosis

International Nuclear Information System (INIS)

Sridhar, K.; Magyar, L.; Lange, R.; McCallum, R.W.

1985-01-01

The authors studied gastric emptying (GE) in patients with peripheral manifestations of progressive systemic sclerosis (PSS) using a radionuclide method. 18 patients underwent esophageal manometry and a GE study using chicken liver labeled in vivo with Tc-99m sulfur colloid as a marker of solid emptying. GE was also measured in 13 normal volunteers. 4 PSS patients with normal esophageal motility also had normal GE. The GE of 14 PSS patients with abnormal esophageal motility was significantly (p < 0.05) delayed; with 67.4% retention of isotope after 2 hours compared to 49.8 in normals. The authors conclude that GE of solids is slow in approximately 2/3 of PSS patients with abnormal esophageal motility but is normal if the esophagus is uninvolved; Delayed GE may contribute to the severity of gastroesophageal reflux in PSS patients and the degree of dysphasgia; and Metoclopramide accelerates GE in PSS patients and should have a valuable therapeutic role

IS THE POLISH TAX SYSTEM PROGRESSIVE? ANALYSIS OF THE TAX BURDEN DEPENDING ON THE TYPE OF EMPLOYMENT

OpenAIRE

Piwowarski, Radosław

2016-01-01

Most of European Union countries apply progressive personal income taxes (PIT). This is the result of the vertical equity principle application, which allows for redistributive fiscal policy. In Poland the mixed system it adopted. Beside the tax payment based on the traditional progressive tax scale, since 2004 self-employed person being non-agricultural entrepreneur may choose tax payment according to 19% flat rate tax. The aim of the study is to analyze the progressiveness of the Polish tax...

Making Progress: The Use of Multiple Progress Reports to Enhance Advertising Students' Media Plan Term Projects

Science.gov (United States)

Kritz, Gary H.; Lozada, Hector R.; Long, Mary M.

2007-01-01

Since the AACSB mandates that students demonstrate effective oral and written communication skills, it is imperative that business professors do what is necessary to improve such skills. The authors investigate whether the use of using multiple progress reports in an Advertising class project improves the final product. The data results show that…

Nuclear Physics Laboratory, University of Colorado, Final Progress Report 14 February 2004

International Nuclear Information System (INIS)

Kinney, E.R.

2004-01-01

OAK-B135 The results and progress of research funded by DOE grant number DOE-FG03-95ER40913 at the University of Colorado at Boulder is described. Includes work performed at the HERMES experiment at DESY to study the quark structure of the nucleon and the hadronization process in nuclei, as well as hadronic reactions studied at LAMPF, KEK, and Fermilab

Experimental research progress on passive safety systems of Chinese advanced PWR

International Nuclear Information System (INIS)

Xiao Zejun; Zhuo Wenbin; Zheng Hua; Chen Bingde; Zong Guifang; Jia Dounan

2003-01-01

TMI and Chernobyl accidents, having pronounced impact on nuclear industries, triggered the governments as well as interested institutions to devote much attention to the safety of nuclear power plant and public's requirements on nuclear power plant safety were also going to be stricter and stricter. It is obvious that safety level of an ordinary light water reactor is no longer satisfactory to these requirements. Recently, the safety authorities have recommended the implementation of passive system to improve the safety of nuclear reactors. Passive safety system is one of the main differences between Chinese advanced PWR and other conventional PWR. The working principle of passive safety system is to utilize the gravity, natural convection (natural circulation) and stored energy to implement the system's safety function. Reactors with passive safety systems are not only safer, but also more economical. The passive safety system of Chinese advanced PWR is composed of three independent systems, i.e. passive containment cooling system, passive residual heat removal system and passive core makeup tank injection system. This paper is a summary of experimental research progress on passive containment cooling system, passive residual heat removal system and passive core makeup tank injection system

Can a poverty-reducing and progressive tax and transfer system hurt the poor?

Science.gov (United States)

Higgins, Sean; Lustig, Nora

2016-09-01

To analyze anti-poverty policies in tandem with the taxes used to pay for them, comparisons of poverty before and after taxes and transfers are often used. We show that these comparisons, as well as measures of horizontal equity and progressivity, can fail to capture an important aspect: that a substantial proportion of the poor are made poorer (or non-poor made poor) by the tax and transfer system. We illustrate with data from seventeen developing countries: in fifteen, the fiscal system is poverty-reducing and progressive, but in ten of these at least one-quarter of the poor pay more in taxes than they receive in transfers. We call this fiscal impoverishment, and axiomatically derive a measure of its extent. An analogous measure of fiscal gains of the poor is also derived, and we show that changes in the poverty gap can be decomposed into our axiomatic measures of fiscal impoverishment and gains.

Tokamak poloidal field systems. Progress report, January 1-December 31, 1979

International Nuclear Information System (INIS)

Rogers, J.D.

1980-05-01

Work is reported on the development of superconducting tokamak poloidal field systems (TPFS). Progress is discussed on the design of a 20 MJ, 50 kA, 7.5 T superconducting pulsed energy storage coil operated in a 1 to 2 s bipolar mode from +7.5 T to -7.5 T in 1982. Conductor development for the coil is presented. A facility that uses a traction motor energy transfer system to test coils in the 20 to 100 MJ energy range is discussed. Current interrupter development and testing for protection and energy transfer circuits are also presented. The 400 kJ METS coil test preparation is under way

Recent Progress in Stability and Stabilization of Systems with Time-Delays

Directory of Open Access Journals (Sweden)

Magdi S. Mahmoud

2017-01-01

Full Text Available This paper overviews the research investigations pertaining to stability and stabilization of control systems with time-delays. The prime focus is the fundamental results and recent progress in theory and applications. The overview sheds light on the contemporary development on the linear matrix inequality (LMI techniques in deriving both delay-independent and delay-dependent stability results for time-delay systems. Particular emphases will be placed on issues concerned with the conservatism and the computational complexity of the results. Key technical bounding lemmas and slack variable introduction approaches will be presented. The results will be compared and connections of certain delay-dependent stability results are also discussed.

A progress report on the g-2 storage ring magnet system

International Nuclear Information System (INIS)

Bunce, G.; Cullen, J.; Danby, G.

1995-01-01

The 3.1 GeV muon storage ring for the g-2 experiment at Brookhaven National Laboratory hat three large solenoid magnets that form a continuous 1.451 tesla storage ring dipole with an average beam bond radius of 7.1 metors. In addition to the three storage ring solenoids, there is an inflector dipole with nested dipole coils that create very little stray magnetic field. A superconducting shield on the infractor gets rid of most of the remaining stray flux. This paper reports on the progress made on the storage ring solenoid magnet system and the inflector as of June 1995. The results of cryogenic system tests are briefly reported

International research progress of CFD application in analysis of nuclear power system

International Nuclear Information System (INIS)

Li Linsen; Wang Kan; Song Xiaoming

2009-01-01

This paper introduces the latest international research progress of CFD application in nuclear reactor system analysis. CFD method has been applied to a few 3-D single phase transient simulations, including flow field modeling of the reactor cores, assemblies, and vessel plenums. On the other hand, CFD method applied to reactor system still needs further validation and benchmarking, meanwhile,the application of CFD also needs to be studied, including the setup of the Best Practice Guidelines (BPG). Furthermore, CFD codes are used to couple with thermal-hydraulic system codes or neutronic codes. Eventually, in two phase field and turbulence modeling, CFD codes are still being developed. (authors)

Columbia River system operation review. Final environmental impact statement

International Nuclear Information System (INIS)

1995-11-01

This Appendix C of the Final Environmental Impact Statement for the Columbia River System discusses impacts on andromous fish and juvenile fish transportation. The principal andromous fish in the Columbia basin include salmonid species (Chinook, coho, and sockeye salmon, and steelhead) and nonsalmoinid andromous species (sturgeon, lamprey, and shad). Major sections in this document include the following: background, scope and process; affected environment for salmon and steelhead, shaded, lamprey, sturgeon; study methods; description of alternatives: qualitative and quantitative findings

TARGET 2 and Settlement Finality

Directory of Open Access Journals (Sweden)

Ivan MANGATCHEV

2011-03-01

Full Text Available This article examines how TARGET 2 as system implements the idea of settlement finality regulated by Directive 98/26 EC of the European parliament and of the Council of 19 May 1998 on settlement finality in payment and securities settlement systems (Settlement Finality Directive and Directive 2009/44/EC of the European parliament and of the Council of 6 May 2009 amending Directive 98/26/EC on settlement finality in payment and securities settlement systems and Directive 2002/47/EC on financial collateral arrangements as regards linked systems and credit claims (Directive 2009/44/EC. As the title of the arti and finality of the settlement in this system.

Research progress of free space coherent optical communication

Science.gov (United States)

Tan, Zhenkun; Ke, Xizheng

2018-02-01

This paper mainly introduces the research progress of free space coherent optical communication in Xi'an University of Technology. In recent years, the research on the outer modulation technology of the laser, free-space-to-fiber coupling technique, the design of transmitting and receiving optical antenna, adaptive optical technology with or without wave-front sensor, automatic polarization control technology, frequency stabilization technology, heterodyne detection technology and high speed signal processing technology. Based on the above related research, the digital signal modulation, transmission, detection and data recovery are realized by the heterodyne detection technology in the free space optical communication system, and finally the function of smooth viewing high-definition video is realized.

78 FR 32427 - Notice of Issuance of Final Determination Concerning Multifunctional Digital Imaging Systems

Science.gov (United States)

2013-05-30

... multifunctional digital imaging systems for purposes of U.S. Government procurement. DATES: The final... Determination Concerning Multifunctional Digital Imaging Systems AGENCY: U.S. Customs and Border Protection... country of origin of certain multifunctional digital imaging systems. Based upon the facts presented, CBP...

Progress update on cryogenic system for ARIEL E-linac at TRIUMF

International Nuclear Information System (INIS)

Koveshnikov, A.; Bylinskii, I.; Hodgson, G.; Yosifov, D.

2014-01-01

TRIUMF is involved in a major upgrade. The Advanced Rare IsotopeE Laboratory (ARIEL) has become a fully funded project in July 2010. A 10 mA 50 MeV SRF electron linac (e-linac) operating CW at 1.3 GHz is the key component of this initiative. This machine will serve as a second independent photo-fission driver for Rare Isotope Beams (RIB) production at TRIUMF's Isotope Separator and Accelerator (ISAC) facility. The cryogens delivery system requirements are driven by the electron accelerator cryomodule design [1, 2]. Since commencement of the project in 2010 the cryogenic system of e-linac has moved from the conceptual design phase into engineering design and procurement stage. The present document summarizes the progress in cryogenic system development and construction. Current status of e-linac cryogenic system including details of LN 2 storage and delivery systems, and helium subatmospheric (SA) system is presented. The first phase of e-linac consisting of two cryomodules, cryogens storage, delivery, and distribution systems, and a 600 W class liquid helium cryoplant is scheduled for installation and commissioning by year 2014

Improved Barriers to Turbine Engine Fragments: Final Annual Report

National Research Council Canada - National Science Library

Shockey, Donald

2002-01-01

This final annual technical report describes the progress rnade during year 4 of the SPI International Phase II effort to develop a computational capability for designing lightweight fragment barriers...

New imaging systems in nuclear medicine. Technical progress report, July 1, 1975--March 15, 1976

International Nuclear Information System (INIS)

Brownell, G.L.

1976-01-01

This progress report covers four areas: development of positron instrumentation, development of NUMEDICS computer system and software, application of cyclotron-produced isotopes ( 11 C, 68 Ga, 13 N, 15 O, and 82 Rb), and application of the NUMEDICS computer system in nuclear medicine. The development of transverse section positron imaging has had a significant impact and a positron camera was designed specifically for transverse section imaging of heart and lungs. The computer net (NUMEDICS II) is progressing rapidly in design and software development. Clinical studies have demonstrated the feasibility of measuring cerebral blood flow using a variety of positron emitting radiopharmaceuticals and oxygen utilization using 15 O 2 . Rubidium-82 also appears to be a promising agent for measurement of cerebral blood flow

/sup 131/I albumin study of patients carrying progressive systemic sclerosis

Energy Technology Data Exchange (ETDEWEB)

Cossermelli, W; Carvalho, N; Papaleo Netto, M [Sao Paulo Univ. (Brazil). Centro de Medicina Nuclear

1974-05-01

/sup 131/I albumin metabolic changes were studied in 14 female patients with progressive systemic sclerosis. A statistical study of the gathered data disclosed increased distribution and turnover half-life and diminished turnover rate of radioactive substance. Since T/2 of turnover and turnover rate are the result produced by the albumin synthesis and degradation, they are probably lowered during active disease causing hypoalbuminemia. The aminoacids also are probably absorbed by other protein like the gammaglobuline synthesis.

78 FR 21389 - Notice of Issuance of Final Determination Concerning Certain Ultrasound Systems

Science.gov (United States)

2013-04-10

... following series of tests and system adjustments are performed: Electrical safety testing of the components... devices (printer etc.). An electrical safety test is then performed on the system's final configuration... boards assembled in Malaysia were important to the function of the oscilloscopes and the U.S. firmware...

Recent Progress on Flexible Triboelectric Nanogenerators for SelfPowered Electronics.

Science.gov (United States)

Hinchet, Ronan; Seung, Wanchul; Kim, Sang-Woo

2015-07-20

Recently, smart systems have met with large success. At the origin of the internet of things, they are a key driving force for the development of wireless, sustainable, and independent autonomous smart systems. In this context, autonomy is critical, and despite all the progress that has been made in low-power electronics and batteries, energy harvesters are becoming increasingly important. Thus, harvesting mechanical energy is essential, as it is widespread and abundant in our daily life environment. Among harvesters, flexible triboelectric nanogenerators (TENGs) exhibit good performance, and they are easy to integrate, which makes them perfect candidates for many applications and, therefore, crucial to develop. In this review paper, we first introduce the fundamentals of TENGs, including their four basic operation modes. Then, we discuss the different improvement parameters. We review some progress made in terms of performance and integration that have been possible through the understanding of each operation mode and the development of innovative structures. Finally, we present the latest trends, structures, and materials in view of future improvements and applications. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Performance of stratified thermal-storage system for Oliver Springs Elementary School. Progress report

Energy Technology Data Exchange (ETDEWEB)

Reid, R.L.; Bedinger, A.F.G.

1981-01-01

A progress report is given on the performance of a stratified thermal storage system coupled with a heat recovery refrigeration machine designed to provide space heating, cooling and service water heating. Water storage tanks utilizing a flexible membrane to resist temperature blending will be used as the thermal storage element. The two design goals of the heat recovery and thermal energy storage system are (1) to minimize the need to purchase energy for space heating and cooling and water heating and (2) to minimize electrical demand. An automatic data acquisition system will be used for system performance and data gathering. Data collection is expected to begin in September, 1981.

The Connection between the Thought of Progress and Philosophical Thinking in the West Case Study: Descartes’ Thought System

Directory of Open Access Journals (Sweden)

Seyed Mustafa Shahraeeni

2015-03-01

Full Text Available Thought of progress has been considered as one of the presuppositions of the West modernity. Having accepted this idea, we should regard it as one of the bases and foundations of early modern philosophy, and consider Descartes, known as the father of modern philosophy, as having a major role in its formation. There is a strong relationship between the West philosophical thought and the change of the idea of progress to one of the undisputed facts of the west civilization, and this issue can be seen clearly in Descartes thought system better than anywhere else. The present paper intends to show the leading position of Descartes’ thought system in the institutionalization of the concept of progress in the West philosophical system in three main parts: 1. Authority fighting and its relation with Cartesian’s Doubt, 2. The genuineness of the worldly life in Descartes’ thought system, and 3. Establishing the foundation of modern science. This article is based on the modern forerunners’ change of opinion about the philosophy mission in the world. It  makes attempt to demonstrate in order to achieve the thought of progress, some prerequisites are necessary; and these prerequisite, though not exclusively, in their best and most complete form are generally achieved in the West philosophical thought and are particularly accomplished in Descartes’ philosophy.

Experimental verification of a progressive damage model for composite laminates based on continuum damage mechanics. M.S. Thesis Final Report

Science.gov (United States)

Coats, Timothy William

1994-01-01

Progressive failure is a crucial concern when using laminated composites in structural design. Therefore the ability to model damage and predict the life of laminated composites is vital. The purpose of this research was to experimentally verify the application of the continuum damage model, a progressive failure theory utilizing continuum damage mechanics, to a toughened material system. Damage due to tension-tension fatigue was documented for the IM7/5260 composite laminates. Crack density and delamination surface area were used to calculate matrix cracking and delamination internal state variables, respectively, to predict stiffness loss. A damage dependent finite element code qualitatively predicted trends in transverse matrix cracking, axial splits and local stress-strain distributions for notched quasi-isotropic laminates. The predictions were similar to the experimental data and it was concluded that the continuum damage model provided a good prediction of stiffness loss while qualitatively predicting damage growth in notched laminates.

Enabling health systems transformation: what progress has been made in re-orienting health services?

Science.gov (United States)

Wise, Marilyn; Nutbeam, Don

2007-01-01

The Ottawa Charter has been remarkably influential in guiding the development of the goals and concepts of health promotion, and in shaping global public health practice in the past 20 years. However, of the five action areas identified in the Ottawa Charter, it appears that there has been little systematic attention to the challenge of re-orienting health services, and less than optimal progress in practice. The purposes of re-orienting health services as proposed in the Ottawa Charter were to achieve a better balance in investment between prevention and treatment, and to include a focus on population health outcomes alongside the focus on individual health outcomes. However, there is little evidence that a re-orientation of health services in these terms has occurred systematically anywhere in the world. This is in spite of the fact that direct evidence of the need to re-orient health services and of the potential benefits of doing so has grown substantially since 1986. Patient education, preventive care (screening, immunisation), and organisational and environmental changes by health organisations have all been found to have positive health and environmental outcomes. However, evidence of effectiveness has not been sufficient, on its own, to sway community preferences and political decisions. The lack of progress points to the need for significant re-thinking of the approaches we have adopted to date. The paper proposes a number of ways forward. These include working effectively in partnership with the communities we want to serve to mobilise support for change, and to reinforce this by working more effectively at influencing broader public opinion through the media. The active engagement of clinical health professionals is also identified as crucial to achieving sustainable change. Finally we recognize that by working in partnership with like-minded advocacy organizations, the IUHPE could put its significant knowledge and experience to work in leading action to

Demonstration of a Small Modular Biopower System Using Poultry Litter-Final Report

Energy Technology Data Exchange (ETDEWEB)

John Reardon; Art Lilley

2004-06-15

On-farm conversion of poultry litter into energy is a unique market connected opportunity for commercialization of small modular bioenergy systems. The United States Department of Energy recognized the need in the poultry industry for alternative litter management as an opportunity for bioenergy. The DOE created a relevant topic in the December 2000 release of the small business innovative research (SBIR) grant solicitation. Community Power Corporation responded to this solicitation by proposing the development of a small modular gasification and gas cleanup system to produce separate value streams of clean producer gas and mineral rich solids. This phase II report describes our progress in the development of an on-farm litter to energy system.

Nifedipine and thallium-201 myocardial perfusion in progressive systemic sclerosis

International Nuclear Information System (INIS)

Kahan, A.; Devaux, J.Y.; Amor, B.

1986-01-01

Heart disease in patients with progressive systemic sclerosis may be due in part to myocardial ischemia caused by a disturbance of the coronary microcirculation. To determine whether abnormalities of myocardial perfusion in this disorder are potentially reversible, we evaluated the effect of the coronary vasodilator nifedipine on myocardial perfusion assessed by thallium-201 scanning in 20 patients. Thallium-201 single-photon-emission computerized tomography was performed under control conditions and 90 minutes after 20 mg of oral nifedipine. The mean (+/- SD) number of left ventricular segments with perfusion defects decreased from 5.3 +/- 2.0 to 3.3 +/- 2.2 after nifedipine (P = 0.0003). Perfusion abnormalities were quantified by a perfusion score (0 to 2.0) assigned to each left ventricular segment and by a global perfusion score (0 to 18) for the entire left ventricle. The mean perfusion score in segments with resting defects increased from 0.97 +/- 0.24 to 1.26 +/- 0.44 after nifedipine (P less than 0.00001). The mean global perfusion score increased from 11.2 +/- 1.7 to 12.8 +/- 2.4 after nifedipine (P = 0.003). The global perfusion score increased by at least 2.0 in 10 patients and decreased by at least 2.0 in only 1. These observations reveal short-term improvement in thallium-201 myocardial perfusion with nifedipine in patients with progressive systemic sclerosis. The results are consistent with a potentially reversible abnormality of coronary vasomotion in this disorder, but the long-term therapeutic effects of nifedipine remain to be determined

Chemical Profiles of Microalgae with Emphasis on Lipids: Final Report

Energy Technology Data Exchange (ETDEWEB)

Benemann, J. R.; Tillett, D. M.; Suen, Y.; Hubbard, J.; Tornabene, T. G.

1986-02-01

This final report details progress during the third year of this subcontract. The overall objective of this subcontract was two fold: to provide the analytical capability required for selecting microalgae strains with high energy contents and to develop fundamental knowledge required for optimizing the energy yield from microalgae cultures. The progress made towards these objectives during this year is detailed in this report.

Progress in switching technology for METS systems

International Nuclear Information System (INIS)

Honig, E.M.; Swannack, C.E.; Warren, R.W.; Whitaker, D.H.

1977-01-01

Three distinct sets of switching requirements have emerged from design optimization studies of large superconducting magnetic energy storage systems, such as the METS system to power the adiabatic plasma compression field in the proposed theta-pinch SFTR. Extremely low joule loss cryogenic disconnects are required between storage coils in the liquid helium environment to allow charging the coils in series over a prolonged time, then to isolate the coils for parallel fast discharging into the load. Another switch must break the current in the series charging loop and absorb the energy from the stray inductance. This action will allow the subsequent opening of the cryogenic disconnects under near zero current condition. The current now has been transferred to the many paralleled circuits, each containing a high current, high voltage interrupter. The opening and arc commutation of the interrupter starts the energy transfer into the load. The primary activities associated with cryogenic disconnect have been testing and development of contact materials, configurations, and closing forces for carrying 26 kA with a resistance less than 40 nΩ, and development of an actuating system that is both reliable and fast acting in a liquid helium environment. The charging loop switch will include a continuous duty switch and a vacuum interrupter. The continuous duty switch resistance can be an order of magnitude larger than that of the cryogenic disconnect because it does not present a refrigeration load. The HVDC interrupter must break 26 kA and withstand 60 kV during the energy transfer time of 700 μs. Testing in progress already has shown successful interruption using single vacuum interrupters up to 31 kA and 66 kV

Beam-based alignment and tuning procedures for e+e- collider final focus systems

International Nuclear Information System (INIS)

Bulos, F.; Burke, D.; Helm, R.; Irwin, J.; Odian, A.; Roy, G.; Ruth, R.; Yamamoto

1991-01-01

For future linear colliders, with very small emittances and beam sizes and demanding tolerances on final focus system alignment and magnet errors, it becomes increasingly important to use the beam as a diagnostic tool. The authors report here procedures they have identified and will be implemented in the Final Focus Test Beam at SLAC incorporating (1) quadrupole strength changes, (2) central orbit modifications, (3) spot size measurements, and (4) beam stability monitoring

The Tourism–Development Nexus in sub-Saharan Africa: Progress ...

African Journals Online (AJOL)

The Tourism–Development Nexus in sub-Saharan Africa: Progress and Prospects. ... discussed concerning the impacts of differentiated kinds of tourism: tourism and ... finally, questions around tourism, climate change and the green economy.

Mycophenolate mofetil combined with systemic corticosteroids prevents progression to chronic recurrent inflammation and development of 'sunset glow fundus' in initial-onset acute uveitis associated with Vogt-Koyanagi-Harada disease.

Science.gov (United States)

Abu El-Asrar, Ahmed M; Dosari, Mona; Hemachandran, Suhail; Gikandi, Priscilla W; Al-Muammar, Abdulrahman

2017-02-01

To evaluate the effectiveness and safety of mycophenolate mofetil (MMF) as first-line therapy combined with systemic corticosteroids in initial-onset acute uveitis associated with Vogt-Koyanagi-Harada (VKH) disease. This prospective study included 38 patients (76 eyes). The main outcome measures were final visual acuity, corticosteroid-sparing effect, progression to chronic recurrent granulomatous uveitis and development of complications, particularly 'sunset glow fundus'. The mean follow-up period was 37.0 ± 29.3 (range 9-120 months). Visual acuity of 20/20 was achieved by 93.4% of the eyes. Corticosteroid-sparing effect was achieved in all patients. The mean interval between starting treatment and tapering to 10 mg or less daily was 3.8 ± 1.3 months (range 3-7 months). Twenty-two patients (57.9%) discontinued treatment without relapse of inflammation. The mean time observed off of treatment was 28.1 ± 19.6 months (range 1-60 months). None of the eyes progressed to chronic recurrent granulomatous uveitis. The ocular complications encountered were glaucoma in two eyes (2.6%) and cataract in five eyes (6.6%). None of the eyes developed 'sunset glow fundus', and none of the patients developed any systemic adverse events associated with the treatment. Use of MMF as first-line therapy combined with systemic corticosteroids in patients with initial-onset acute VKH disease prevents progression to chronic recurrent granulomatous inflammation and development of 'sunset glow fundus'. © 2016 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

Disposal Systems Evaluation Framework (DSEF) Version 1.0 - Progress Report

Energy Technology Data Exchange (ETDEWEB)

Sutton, Mark [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Blink, James A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Fratoni, Massimiliano [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Greenberg, Harris R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Halsey, William G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wolery, Thomas J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2011-06-03

The Disposal Systems Evaluation Framework (DSEF) is being developed at Lawrence Livermore National Laboratory to formalize the development and documentation of repository conceptual design options for each waste form and environment combination. This report summarizes current status and plans for the remainder of FY11 and for FY12. This progress report defines the architecture and interface parameters of the DSEF Excel workbook, which contains worksheets that link to each other to provide input and document output from external codes such that concise comparisons between fuel cycles, disposal environments, repository designs and engineered barrier system materials can be performed. Collaborations between other Used Fuel Disposition Campaign work packages and US Department of Energy / Nuclear Energy campaigns are clearly identified. File naming and configuration management is recommended to allow automated abstraction of data from multiple DSEF runs.

[Research programs in radiotherapy]. DOE final report, 1996

International Nuclear Information System (INIS)

DeNardo, S.J.

1996-01-01

Results which have not yet been published in detail are reported here on the following associated studies: Progress in the area of macrocyclic chelates for targeted therapy; Progress in biologic activation with radioimmunoconjugate therapy: Association of molecular receptor increase and tumor response in ChL6/L6 protocol patients; Progress in genetically engineered Lym-1 single chain molecules; Progress in analysis of molecular genetic coded messages to enhance tumor response; Progress on development and validation of planar imaging for therapy planning systems; Progress in development of a 3-D treatment planning system using SPECT; Progress in development of methods to evaluate enhancement of tumor penetration in a murine model; and Progress in clinical applications

[Research programs in radiotherapy]. DOE final report, 1996

Energy Technology Data Exchange (ETDEWEB)

DeNardo, S.J.

1996-12-31

Results which have not yet been published in detail are reported here on the following associated studies: Progress in the area of macrocyclic chelates for targeted therapy; Progress in biologic activation with radioimmunoconjugate therapy: Association of molecular receptor increase and tumor response in ChL6/L6 protocol patients; Progress in genetically engineered Lym-1 single chain molecules; Progress in analysis of molecular genetic coded messages to enhance tumor response; Progress on development and validation of planar imaging for therapy planning systems; Progress in development of a 3-D treatment planning system using SPECT; Progress in development of methods to evaluate enhancement of tumor penetration in a murine model; and Progress in clinical applications.

Opportunities for Collaborative Adaptive Management Progress: Integrating Stakeholder Assessments into Progress Measurement

Directory of Open Access Journals (Sweden)

Jim Berkley

2013-12-01

There are differences among stakeholders in the indicators they consider as relevant to the assessment of progress. Elucidating these differences can provide useful information about system components and relationships that are important to public support of a CAM program and progress. One of the sources of differences in progress assessments among stakeholders comes from their diverse perceptions about the desired and current states of the social-ecological systems. Stakeholder behavior can be inconsistent between group and individual settings. Individually they may make plans, based on their assessments, that do not conform to the group plan because of their unique interests and preferences. The results of this study need to be further tested. The framework should be used through multiple cycles to determine whether the information gathered with this approach results in additional progress as compared with past approaches. In particular, it would be helpful to test whether gathering such information resulted in a decrease in stakeholders electing to go outside of the CAM process to get their needs met.

SPEAR 3 Upgrade Project: The Final Year

International Nuclear Information System (INIS)

Hettel, R

2004-01-01

During April, 2003, the SPEAR 2 storage ring, which served the high energy physics community from 1972 to 1987, and the synchrotron radiation community for an additional 15 years, was removed from its shielding tunnel in order to install the new 3-GeV, 500-mA SPEAR 3 light source. From May to November, SSRL will excavate the tunnel floor and pour a new concrete floor, and then install pre-assembled girders holding magnets, copper vacuum chambers, PEP-II-style rf cavities, and beam line front end components. At the same time, power supply, instrumentation and control, and other ancillary systems will be configured, leading to a commissioning period beginning in November 2003. The progress of accelerator component implementation and installation during the final year of the project will be reviewed

Beam-based alignment and tuning procedures for e+e- collider final focus systems

International Nuclear Information System (INIS)

Bulos, F.; Burke, D.; Helm, R.; Irwin, J.; Odian, A.; Roy, G.; Ruth, R.; Yamamoto, N.

1991-05-01

For future linear colliders, with very small emittances and beam sizes and demanding tolerances on final focus system alignment and magnet errors, it becomes increasingly important to use the beam as a diagnostic tool. We report here procedures we have identified and will be implemented in the Final Focus Test Beam at SLAC incorporating (1) quadrupole strength changes, (2) central orbit modifications, (3) spot size measurements, and (4) beam stability monitoring. 3 refs., 4 figs., 3 tabs

Disruption of spatial organization and interjoint coordination in Parkinson's disease, progressive supranuclear palsy, and multiple system atrophy.

Science.gov (United States)

Leiguarda, R; Merello, M; Balej, J; Starkstein, S; Nogues, M; Marsden, C D

2000-07-01

Patients with basal ganglia diseases may exhibit ideomotor apraxia. To define the nature of the impairment of the action production system, we studied a repetitive gesture of slicing bread by three-dimensional computergraphic analysis in eight nondemented patients with Parkinson's disease in the "on" state, five with progressive supranuclear palsy and four with multiple system atrophy. Two patients with Parkinson's disease and two with progressive supranuclear palsy showed ideomotor apraxia for transitive movements on standard testing. A Selspott II system was used for kinematic analysis of wrist trajectories and angular motions of the shoulder and elbow joints. Patients with Parkinson's disease, progressive supranuclear palsy, and even some with multiple system atrophy exhibited kinematic deficits in the spatial precision of movement and velocity-curvature relationships; in addition, they failed to maintain proper angle/angle relationships and to apportion their relative joint amplitudes normally. Spatial disruption of wrist trajectories was more severe in patients with ideomotor apraxia. We posit that the basal ganglia are part of the parallel parieto-frontal circuits devoted to sensorimotor integration for object-oriented behavior. The severity and characteristics of spatial abnormalities of a transitive movement would therefore depend on the location and distribution of the pathologic process within these circuits.

System composition and operation of exposure dose registration and control system (Final report)

International Nuclear Information System (INIS)

1978-01-01

Since November, 1976, the committee concerning the investigation of exposure dose registration and control system for employees in nuclear industries has discussed on the exposure dose registration and control system, issued the interim report (outline) in April, 1977, and continued to investigate the details organizing the working group. Here, the final report is presented. It describes first on the definition of the terms used and the basic concept of the exposure dose registration and control system, in which the name of that organization is decided as ''Central Registration Office for Radiation Works'', Radiation Influence Association, the foundational juridical person. Next, the works to be performed in the Center and nuclear energy enterprises are explained. The items concerning the business management at the time of practical execution are the major part of the report, and are over 22 items. These include the registration business, the official reporting business, inquiry and answer business about career, change and revision, and computer processing system. As the temporary measures for transfer ring to the new system, 10 items are also provided. Supplementary explanation of 9 important items is given in the appendix. (Wakatsuki, Y.)

PFBC HGCU Test Facility. Technical progress report No. 24, Third quarter, CY 1995

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-10-01

This is the twenty-fourth and final Technical Progress Report submitted to the Department of Energy (DOE) in connection with the cooperative agreement between the DOE and Ohio Power Company for the Tidd PFBC Hot Gas Clean Up Test Facility. This report covers the work completed during the Third Quarter of CY 1995. All activity this quarter was directed toward the completion of the program final report. A draft copy of the final report was forwarded to DOE during this quarter, and DOE submitted their comments on the report to AEPSC. DOE requested that Westinghouse write an appendix to the report covering the performance of the fail-safe regenerator devices during Tad operation, and Westinghouse subsequently prepared the appendix. Additional DOE comments were incorporated into the report, and it will be issued in camera-ready form by the end of October, 1995, which is the program end date. Appendix 1 presents the results of filter candle posttest examination by Westinghouse performed on selected filter candles following final shutdown of the system.

Progress update on cryogenic system for ARIEL E-linac at TRIUMF

Energy Technology Data Exchange (ETDEWEB)

Koveshnikov, A.; Bylinskii, I.; Hodgson, G.; Yosifov, D. [TRIUMF, Vancouver, BC, V6T 2A3 (Canada)

2014-01-29

TRIUMF is involved in a major upgrade. The Advanced Rare IsotopeE Laboratory (ARIEL) has become a fully funded project in July 2010. A 10 mA 50 MeV SRF electron linac (e-linac) operating CW at 1.3 GHz is the key component of this initiative. This machine will serve as a second independent photo-fission driver for Rare Isotope Beams (RIB) production at TRIUMF's Isotope Separator and Accelerator (ISAC) facility. The cryogens delivery system requirements are driven by the electron accelerator cryomodule design [1, 2]. Since commencement of the project in 2010 the cryogenic system of e-linac has moved from the conceptual design phase into engineering design and procurement stage. The present document summarizes the progress in cryogenic system development and construction. Current status of e-linac cryogenic system including details of LN{sub 2} storage and delivery systems, and helium subatmospheric (SA) system is presented. The first phase of e-linac consisting of two cryomodules, cryogens storage, delivery, and distribution systems, and a 600 W class liquid helium cryoplant is scheduled for installation and commissioning by year 2014.

75 FR 11002 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Final Rule

Science.gov (United States)

2010-03-10

... Waste Management System; Identification and Listing of Hazardous Waste; Final Rule AGENCY: Environmental... and specific types of management of the petitioned waste, the quantities of waste generated, and waste... wastes. This final rule responds to a petition submitted by Valero to delist F037 waste. The F037 waste...

Final design and status of the NSLS vacuum system

International Nuclear Information System (INIS)

Schuchman, J.C.

1982-01-01

We describe the final system, as built, reasons for changes and the general status of the NSLS. The NSLS is a dedicated facility for the purpose of producing synchrotron radiation. It consists of an electron linac-booster injector system, and two storage rings, one for uv research and the other for x-ray research. (Synchrotron radiation is produced by accelerating electrons in the storage rings.) The design current and energies are 1000 ma at 700 MeV for the vuv ring and 500 ma at 2.5 GeV for the x-ray ring. A total of 44 experimental beam ports are available for use. Since each beam port may be divided into two or more experimentall beam lines, it is quite plausible to have upward of 100 simultaneously operating beam lines

Recent progress of China HCCB TBM tritium system

Energy Technology Data Exchange (ETDEWEB)

Luo, Deli, E-mail: luodeli2005@hotmail.com; Huang, Guoqiang; Huang, Zhiyong; Qin, Cheng; Song, Jiangfeng; He, Kanghao; Chen, Chang’an; Zhang, Guikai; Fu, Jun; Yao, Yong; An, Yongtao

2016-11-01

Highlights: • Comparing with our previous design, improvements have been made according to the up-to-date experiments and simulations: (1) The palladium alloy tube in the previous design is now removed in the upgraded one and the cryogenic molecular sieve bed is replaced by the getter bed to reduce tritium inventory; (2) Hot metal reduction bed is relocated from T-Plant to Port Cell; (3) TAS is now integrated into TES. • The proposed coolant purification is based on catalytic oxidation and molecular sieve bed adsorption for tritium removal, as well as hot metal adsorption for the elimination of non-tritium gaseous impurities. Some operation parameters and functional components are improved. The interface with the high pressure HCS and other plant systems was incorporated taking into account of the requirement from the ITER port management group meetings. - Abstract: China tritium system including Tritium Extraction System (TES) with Tritium Accountancy System (TAS) integrated in and Coolant Purification System (CPS), which is subordinate to Helium Coolant System (HCS), is of great importance for China Helium Cooled Ceramic Breeder Test Blanket Module (CN HCCB TBM). The purge gas (99.9% He + 0.1% H{sub 2}) carrying Q{sub 2}O (Q = H, D, T) and Q{sub 2} from Li{sub 4}SiO{sub 4} ceramic breeder flows through the reduction bed where Q{sub 2}O is reduced into Q{sub 2} and then absorbed by the getter bed. The HT/HTO ratio and the total tritium are determined by TAS. Catalytic oxidation combines with molecular sieve absorption and hot metal purification are applied to remove tritium and other impurities in helium coolant. A loop including depressurization, helium-sweeping assisted thermal desorption, and cold trapping for the regeneration of saturated molecular sieve bed until the concentration of the desorbed Q{sub 2}O is reduced to an acceptable level. This paper introduces the recent progress of China tritium system including updated conceptual designs of TES and

Low-dose fractionated radiotherapy and concomitant chemotherapy for recurrent or progressive glioblastoma. Final report of a pilot study

Energy Technology Data Exchange (ETDEWEB)

Balducci, M.; Diletto, B.; Chiesa, S.; D' Agostino, G.R.; Gambacorta, M.A.; Ferro, M.; Valentini, V. [Catholic University of the Sacred Heart, Department of Radiation Oncology, Rome (Italy); Colosimo, C. [Catholic University of the Sacred Heart, Department of Radiology, Rome (Italy); Maira, G.; Anile, C. [Catholic University of the Sacred Heart, Department of Neurosurgery, Rome (Italy)

2014-04-15

Evaluated in this study were the feasibility and the efficacy of concurrent low dose fractionated radiotherapy (LD-FRT) and chemotherapy as palliative treatment for recurrent/progressive glioblastoma multiforme (GBM). Eligible patients had recurrent or progressive GBM, Karnofsky performance status ≥70, prior surgery, and standard radiochemotherapy treatment. Recurrence/progression disease during temozolomide (TMZ) received cisplatin (CDDP; 30 mg/m{sup 2} on days 1, 8, 15), fotemustine (FTM; 40 mg/m{sup 2} on days 2, 9, 16), and concurrent LD-FRT (0.3 Gy twice daily); recurrence/progression after 4 months from the end of adjuvant TMZ were treated by TMZ (150/200 mg/m{sup 2} on days 1-5) concomitant with LD-FRT (0.4 Gy twice daily). Primary endpoints were safety and toxicity. A total of 32 patients were enrolled. Hematologic toxicity G1-2 was observed in 18.7% of patients and G3-4 in 9.4%. One patient (3.1%) had complete response, 3 (9.4%) had partial response, 8 (25%) had stable disease for at least 8 weeks, while 20 patients (62.5%) experienced progressive disease. The clinical benefit was 37.5%. Median progression-free survival (PFS) and overall survival (OS) were 5 and 8 months, respectively. Survival rate at 12 months was of 27.8%. LD-FRT and chemotherapy for recurrent/progressive GBM have a good toxicity profile and clinical outcomes, even though further investigation of this novel palliative treatment approach is warranted. (orig.)

Tokamak poloidal field systems. Progress report, January 1-December 31, 1980

International Nuclear Information System (INIS)

Rogers, J.D.

1981-03-01

Work is reported on the development of superconducting tokamak poloidal field system (TPFS) program. Progress is discussed on the design of the 20 MJ, 50 kA, 7.5 T superconducting pulsed energy storage coil to be operated in a bipolar mode from +7.5 T to -7.5 T in an energy transfer period of 1.5 to 5 s in 1982 followed by extensive cyclic testing. The facility to conduct the tests uses a traction motor energy transfer system and a nonconducting dewar. Status of the hardware development for the TPFS program is presented. Current interrupter development and testing for protection and energy transfer circuits are also presented. The 400 kJ METS coil test results are given

TRICARE revision to CHAMPUS DRG-based payment system, pricing of hospital claims. Final rule.

Science.gov (United States)

2014-05-21

This Final rule changes TRICARE's current regulatory provision for inpatient hospital claims priced under the DRG-based payment system. Claims are currently priced by using the rates and weights that are in effect on a beneficiary's date of admission. This Final rule changes that provision to price such claims by using the rates and weights that are in effect on a beneficiary's date of discharge.

Final report for the 'Melt-Vessel Interactions' Project. European Union R and TD Program 4th Framework. MVI project final research report

International Nuclear Information System (INIS)

Sehgal, B.R.; Dinh, T.N.; Nourgaliev, R.R.; Bui, V.A.; Green, J.; Kolb, G.; Karbojian, A.; Theerthan, S.A.; Gubaidulline, A.; Bonnet, J.M.; Rouge, S.; Narcoux, M.; Liegeois, A.; Turland, B.D.; Dobson, G.P.; Siccama, A.; Ikonen, K.; Parozzi, F.; Kolev, N.; Caira, M.

1999-04-01

The Melt Vessel Interaction (MVI) project is concerned with the consequences of the interactions that a core melt, generated during a postulated severe accident in a light water reactor, may have with the pressure vessel. In particular, the issues concerned with the failure of the vessel bottom head are the focus of the research. The specific objectives of the project are to obtain data and develop validated models, which could be applied to prototypic plants, and accident conditions, for resolution of issues related to the melt vessel interactions. The project work has been performed by nine partners having varied responsibility. The work included a large number of experiments, with simulant materials, whose observations and results are employed, respectively, to understand the physical mechanisms and to develop validated models. Applications to the prototypic geometry and conditions have also been performed. This report is volume 1 of the Final Report for the Project, in which a summary of the progress achieved in the experimental program is provided. We have, however, included some aspects of the modeling activities. Volume 2 of the Final report describes the progress achieved in the modeling program. The progress achieved in the experimental and modeling parts of the Project has led to the resolution of some of the issues of melt vessel interaction. Considerable progress was also achieved towards resolution of the remaining issues

MULTIPLE PROJECTIONS SYSTEM (MPS) - USER'S MANUAL VERSION 1.0

Science.gov (United States)

The report is a user's manual for version 1.0 of the Multiple Projections Systems (MPS), a computer system that can perform "what if" scenario analysis and report the final results (i.e., Rate of Further Progress - ROP - inventories) to EPA (i.e., the Aerometric Information Retri...

[Progressive visual agnosia].

Science.gov (United States)

Sugimoto, Azusa; Futamura, Akinori; Kawamura, Mitsuru

2011-10-01

Progressive visual agnosia was discovered in the 20th century following the discovery of classical non-progressive visual agnosia. In contrast to the classical type, which is caused by cerebral vascular disease or traumatic injury, progressive visual agnosia is a symptom of neurological degeneration. The condition of progressive visual loss, including visual agnosia, and posterior cerebral atrophy was named posterior cortical atrophy (PCA) by Benson et al. (1988). Progressive visual agnosia is also observed in semantic dementia (SD) and other degenerative diseases, but there is a difference in the subtype of visual agnosia associated with these diseases. Lissauer (1890) classified visual agnosia into apperceptive and associative types, and it in most cases, PCA is associated with the apperceptive type. However, SD patients exhibit symptoms of associative visual agnosia before changing to those of semantic memory disorder. Insights into progressive visual agnosia have helped us understand the visual system and discover how we "perceive" the outer world neuronally, with regard to consciousness. Although PCA is a type of atypical dementia, its diagnosis is important to enable patients to live better lives with appropriate functional support.

Renal diagnostic nuclear medicine procedures in progressive systemic scleroderma (PSS)

Energy Technology Data Exchange (ETDEWEB)

Ammari, B.; Hotze, A.; Gruenwald, F.; Biersack, H.J.; Blitz, H.; Kuester, W.; Kreysel, H.W.

1989-02-01

The involvement of kidneys in progressive systemic scleroderma (PSS) is one of the most frequent causes of death in this disease. Using clinical criteria and laboratory tests only the frequency of kidney involvement would be clearly underestimated. Invasive diagnostic procedures such as biopsy and angiography can not be applied in those patients. Nuclear medicine techniques (hippurate clearance, DMSA-scan), however, offer non invasive and sensitive methods in the diagnosis of renal involvement in PSS patients. In our study 46 of 76 patients (60%) revealed pathologic findings. The mentioned diagnostic techniques show a high sensitivity and are in agreement with pathological findings described in PSS.

Renal diagnostic nuclear medicine procedures in progressive systemic scleroderma (PSS)

International Nuclear Information System (INIS)

Ammari, B.; Hotze, A.; Gruenwald, F.; Biersack, H.J.; Blitz, H.; Kuester, W.; Kreysel, H.W.

1989-01-01

The involvement of kidneys in progressive systemic scleroderma (PSS) is one of the most frequent causes of death in this disease. Using clinical criteria and laboratory tests only the frequency of kidney involvement would be clearly underestimated. Invasive diagnostic procedures such as biopsy and angiography can not be applied in those patients. Nuclear medicine techniques (hippurate clearance, DMSA-scan), however, offer non invasive and sensitive methods in the diagnosis of renal involvement in PSS patients. In our study 46 of 76 patients (60%) revealed pathologic findings. The mentioned diagnostic techniques show a high sensitivity and are in agreement with pathological findings described in PSS. (orig.) [de

Total System Performance Assessment Sensitivity Analyses for Final Nuclear Regulatory Commission Regulations

International Nuclear Information System (INIS)

Bechtel SAIC Company

2001-01-01

This Letter Report presents the results of supplemental evaluations and analyses designed to assess long-term performance of the potential repository at Yucca Mountain. The evaluations were developed in the context of the Nuclear Regulatory Commission (NRC) final public regulation, or rule, 10 CFR Part 63 (66 FR 55732 [DIRS 156671]), which was issued on November 2, 2001. This Letter Report addresses the issues identified in the Department of Energy (DOE) technical direction letter dated October 2, 2001 (Adams 2001 [DIRS 156708]). The main objective of this Letter Report is to evaluate performance of the potential Yucca Mountain repository using assumptions consistent with performance-assessment-related provisions of 10 CFR Part 63. The incorporation of the final Environmental Protection Agency (EPA) standard, 40 CFR Part 197 (66 FR 32074 [DIRS 155216]), and the analysis of the effect of the 40 CFR Part 197 EPA final rule on long-term repository performance are presented in the Total System Performance Assessment--Analyses for Disposal of Commercial and DOE Waste Inventories at Yucca Mountain--Input to Final Environmental Impact Statement and Site Suitability Evaluation (BSC 2001 [DIRS 156460]), referred to hereafter as the FEIS/SSE Letter Report. The Total System Performance Assessment (TSPA) analyses conducted and documented prior to promulgation of the NRC final rule 10 CFR Part 63 (66 FR 55732 [DIRS 156671]), were based on the NRC proposed rule (64 FR 8640 [DIRS 101680]). Slight differences exist between the NRC's proposed and final rules which were not within the scope of the FEIS/SSE Letter Report (BSC 2001 [DIRS 156460]), the Preliminary Site Suitability Evaluation (PSSE) (DOE 2001 [DIRS 155743]), and supporting documents for these reports. These differences include (1) the possible treatment of ''unlikely'' features, events and processes (FEPs) in evaluation of both the groundwater protection standard and the human-intrusion scenario of the individual

Final progress report

International Nuclear Information System (INIS)

Blann, M.

1978-01-01

A summary is given of the main contributions made under the subject contract. A list of publications resulting therefrom, conference addresses, and contributed papers is appended. Titles of Ph.D. theses, M.S. theses, and the names of students doing the work are also summarized

Progressive taxation and the subjective well-being of nations.

Science.gov (United States)

Oishi, Shigehiro; Schimmack, Ulrich; Diener, Ed

2012-01-01

Using data from the Gallup World Poll, we examined whether progressive taxation is associated with increased levels of subjective well-being. Consistent with Rawls's theory of justice, our results showed that progressive taxation was positively associated with the subjective well-being of nations. However, the overall tax rate and government spending were not associated with the subjective well-being of nations. Furthermore, controlling for the wealth of nations and income inequality, we found that respondents living in a nation with more-progressive taxation evaluated their lives as closer to the best possible life and reported having more positive and less negative daily experiences than did respondents living in a nation with less-progressive taxation. Finally, we found that the association between more-progressive taxation and higher levels of subjective well-being was mediated by citizens' satisfaction with public goods, such as education and public transportation.

Instrumentation of dynamic gas pulse loading system. Technical progress report, first quarter 1992

Energy Technology Data Exchange (ETDEWEB)

Mohaupt, H.

1992-04-14

The overall goal of this work is to further develop and field test a system of stimulating oil and gas wells, which increases the effective radius of the well bore so that more oil can flow into it, by recording pressure during the gas generation phase in real time so that fractures can be induced more predictably in the producing formation. Task 1: Complete the laboratory studies currently underway with the prototype model of the instrumentation currently being studied. Task 2: Perform field tests of the model in the Taft/Bakersfield area, utilizing operations closest to the engineers working on the project, and optimize the unit for various conditions encountered there. Task 3: Perform field test of the model in DGPL jobs which are scheduled in the mid-continent area, and optimize the unit for downhole conditions encountered there. Task 4: Analyze and summarize the results achieved during the complete test series, documenting the steps for usage of downhole instrumentation in the field, and compile data specifying use of the technology by others. Task 5: Prepare final report for DOE, and include also a report on the field tests completed. Describe and estimate the probability of the technology being commercialized and in what time span. The project has made substantial technical progress, though we are running about a month behind schedule. Expenditures are in line with the schedule. Increased widespread interest in the use of DGPL stimulation has kept us very busy. The computer modeling and test instrumentation developed under this program is already being applied to commercial operations.

Tracking Clean Energy Progress 2013

Energy Technology Data Exchange (ETDEWEB)

NONE

2013-06-01

Tracking Clean Energy Progress 2013 (TCEP 2013) examines progress in the development and deployment of key clean energy technologies. Each technology and sector is tracked against interim 2020 targets in the IEA Energy Technology Perspectives 2012 2°C scenario, which lays out pathways to a sustainable energy system in 2050. Stark message emerge: progress has not been fast enough; large market failures are preventing clean energy solutions from being taken up; considerable energy efficiency remains untapped; policies need to better address the energy system as a whole; and energy-related research, development and demonstration need to accelerate. Alongside these grim conclusions there is positive news. In 2012, hybrid-electric vehicle sales passed the 1 million mark. Solar photovoltaic systems were being installed at a record pace. The costs of most clean energy technologies fell more rapidly than anticipated.

Fusion-reactor physics and technology studies. Progress report, December 1, 1982-June 30, 1983

International Nuclear Information System (INIS)

Kulcinski, G.L.; Emmert, G.A.; Maynard, C.W.

1983-01-01

The work performed during the past fiscal year (1983) was directed almost entirely towards the MARS project. This tandem mirror reactor design study is due to be finished in September of 1983 and a final report will be issued at that time. The present report mainly covers progress made after the interim report and is meant to supplement information in UCRL-53333. The areas covered in this present report are: (1) blanket design improvements; (2) end cell neutronics; (3) RF heating systems; (4) economic optimization of blanket; (5) plasma startup; (6) Li 17 Pb 83 corrosion; (7) double walled steam generator analysis; and (8) tritium system

Progress in JT-60 joint research

International Nuclear Information System (INIS)

Kimura, Haruyuki; Kikuchi, Mitsuru; Inutake, Masaaki

2007-01-01

It consists of five chapters; 1) introduction, 2) management system of joint plan and researches, 3) progress of joint researches, 4) results of researches and 5) summary. The second chapter stated the structure of management system of JT-60 joint researches, progress of management of the JT-60 experimental theme system, invitation the public to joint researches and selection of the subjects. The progress of joint researches contained the number of subjects, research members and organizations, change of joint research fields, remote control system of experiments, analysis code group, and number of reports. The main results of researches such as development of operation without center solenoid, Magneto-Hydro-Dynamics (MHD) control by electron cyclotron wave, plasma-wall interaction, application of laser technologies to plasma measurement, and comparison between tokamak and helical are reported. (S.Y.)

Freight Advanced Traveler Information System (FRATIS) - Dallas-Fort Worth (DFW) prototype : final report.

Science.gov (United States)

This is the Final Report for the FRATIS Dallas-Fort Worth DFW prototype system. The FRATIS prototype in : DFW consisted of the following components: optimization algorithm, terminal wait time, route specific : navigation/traffic/weather, and advanced...

Abiraterone acetate for patients with metastatic castration-resistant prostate cancer progressing after chemotherapy

DEFF Research Database (Denmark)

Sternberg, Cora N; Castellano, Daniel; Daugaard, Gedske

2014-01-01

, development of sustained side-effects, or abiraterone acetate becoming available in the respective country. The primary outcome was the number of adverse events arising during study treatment and within 30 days of discontinuation. Efficacy measures (time to prostate-specific antigen [PSA] progression and time......BACKGROUND: In the final analysis of the phase 3 COU-AA-301 study, abiraterone acetate plus prednisone significantly prolonged overall survival compared with prednisone alone in patients with metastatic castration-resistant prostate cancer progressing after chemotherapy. Here, we present the final...... analysis of an early-access protocol trial that was initiated after completion of COU-AA-301 to enable worldwide preapproval access to abiraterone acetate in patients with metastatic castration-resistant prostate cancer progressing after chemotherapy. METHODS: We did a multicentre, open-label, early...

Four centuries on from Bacon: progress in building health research systems to improve health systems?

Science.gov (United States)

Hanney, Stephen R; González-Block, Miguel A

2014-09-23

In 1627, Francis Bacon's New Atlantis described a utopian society in which an embryonic research system contributed to meeting the needs of the society. In this editorial, we use some of the aspirations described in New Atlantis to provide a context within which to consider recent progress in building health research systems to improve health systems and population health. In particular, we reflect on efforts to build research capacity, link research to policy, identify the wider impacts made by the science, and generally build fully functioning research systems to address the needs identified. In 2014, Health Research Policy and Systems has continued to publish one-off papers and article collections covering a range of these issues in both high income countries and low- and middle-income countries. Analysis of these contributions, in the context of some earlier ones, is brought together to identify achievements, challenges and possible ways forward. We show how 2014 is likely to be a pivotal year in the development of ways to assess the impact of health research on policies, practice, health systems, population health, and economic benefits.We demonstrate how the increasing focus on health research systems will contribute to realising the hopes expressed in the World Health Report, 2013, namely that all nations would take a systematic approach to evaluating the outputs and applications resulting from their research investment.

Radiation chemistry of hydrocarbon and alkyl halide systems. Interim progress report, June 1, 1984-July 31, 1985

International Nuclear Information System (INIS)

Hanrahan, R.J.

1985-01-01

Experimental work in progress includes studies of gas phase OH radical reaction using argon sensitized pulse radiolysis and studies of the radiolytic oxidation of butane. Work on interpretation of results, writing, and revision of manuscripts is still in progress on several investigations including studies of the photochemistry and mass spectrometry of CF3I-CH3I mixtures; an investigation of the radiolytic oxidation of propane; and certain parts of the study of radiolytic reactions in the H 2 - CO system. Work on experimental aspects of the radiolytic oxidation of butane nearing completion. It appears that the results do parallel the propane system as we anticipated, with major products being the C 4 alcohols and olefins

Progress in fusion technology at SWIP

Energy Technology Data Exchange (ETDEWEB)

Duan, X.R., E-mail: duanxr@swip.ac.cn; Chen, J.M.; Feng, K.M.; Liu, X.; Li, B.; Wu, J.H.; Wang, X.Y.; Zheng, P.F.; Wang, Y.Q.; Wang, P.H.; Liu, Yong

2016-11-01

Highlights: • Dispersion strengthened CLF-1 steel, vanadium alloys and tungsten alloys are developed. • The HCCB TBM conceptual design, development of functional materials such as Li{sub 4}SiO{sub 4} pebbles and Be pebbles are in progress. • A full size prototype shield block has been fabricated and passed ITER qualification. • Advanced divertor for a new tokamak are designed and analyzed. • GIS and GDC have entered the engineering design phase. - Abstract: The fusion research activities at Southwestern Institute of Physics (SWIP) include the HL-2A & HL-2M tokamak programs, fusion reactor design and materials, along with key fusion technologies including R&D on ITER procurement packages. This paper presents the progress of fusion technology at SWIP, including the ITER first wall and blanket, Chinese helium cooled ceramic breeder test blanket module (HCCB–TBM) for ITER, gas injection system and gas discharge cleaning system, as well as the recent activities on reactor materials and R&D related to advanced divertor. The final design for ITER first wall and blanket shielding blocks allocated to SWIP have been completed, and were validated by recent tests. Major manufacturing technologies, such as forging, deep drilling, explosion bonding and deep laser welding, have been successfully demonstrated. Furthermore, the conceptual design of CN–HCCB–TBM has been completed, the related materials’ preparation, mock-up manufacturing and tests have been implemented. The tungsten divertor has been studied with various bonding and coating technologies. Meanwhile, highlights of functional material for TBM, oxides and carbides dispersion strengthened (ODS, CDS) reduced activation ferritic/martensitic (RAFM) steel, vanadium and tungsten alloys are also presented.

Shock stability in systems that change type. Final grant report to the Department of Energy

International Nuclear Information System (INIS)

Keyfitz, B.L.

1995-01-01

The aim of the original project was to investigate systems of conservation laws that change type. Progress was made on this problem. During the last period of the grant, the author began an investigation of a multidimensional system related to Mach reflection which goes beyond the original work proposed. This has been fruitful direction in which to apply expertise on change of type. Some basic theoretical results have been found

Progress Report for Period Ending December 1961. Department of Reactor Physics

Energy Technology Data Exchange (ETDEWEB)

Tell, B [ed.

1962-08-15

This is the second Progress Report from the Department for Reactor Physics of Aktiebolaget Atomenergi, which is issued for the information of institutions and persons interested in the progress of the work. In this report the activities of the General Physics Section have been included, since this section nowadays belongs to the department. This is merely an informal progress report, and the results and data presented must be taken as preliminary. Final results will be submitted for publication either in the regular technical journals or as monographs in the series AE-reports.

Midwives and obstetric nurses in the Brazilian Unified Health System and Primary Health Care: for a systemic and progressive incorporation

OpenAIRE

Armando Henrique Norman; Charles Dalcanale Tesser

2015-01-01

The objective of this paper is to present a proposal for a gradual and systemic incorporation of midwives and obstetric nurses into the Brazilian Unified Health System (SUS) and Primary Health Care (PHC). The proposal was born from contact with the British experience, based on midwives, which is briefly described. In Brazil, these professionals would progressively take over the prenatal, delivery and postpartum care for pregnant women of usual risk in a region, in partnership with the PHC tea...

Progressive multifocal leukoencephalopathy restricted to the posterior fossa in a patient with systemic lupus erythematosus

Energy Technology Data Exchange (ETDEWEB)

Goncalves, Fabricio Guimaraes; Lamb, Leslie; Del Carpio-O' Donovan, Raquel, E-mail: goncalves.neuroradio@gmail.com [McGill University Health Center Montreal General Hospital (Canada)

2011-11-15

Progressive multifocal leukoencephalopathy is a neurological infectious disease caused by the John Cunningham polyoma virus (JCV), an opportunistic agent with worldwide distribution. This disease is frequently seen in immunosuppressed patients and rarely associated with systemic lupus erythematosus. In the central nervous system PML demyelinating lesions occur in the supratentorial compartment. The authors describe a rare case of PML secondary to SLE treatment with atypical presentation restricted to the posterior fossa (author)

Progressive multifocal leukoencephalopathy restricted to the posterior fossa in a patient with systemic lupus erythematosus

International Nuclear Information System (INIS)

Goncalves, Fabricio Guimaraes; Lamb, Leslie; Del Carpio-O'Donovan, Raquel

2011-01-01

Progressive multifocal leukoencephalopathy is a neurological infectious disease caused by the John Cunningham polyoma virus (JCV), an opportunistic agent with worldwide distribution. This disease is frequently seen in immunosuppressed patients and rarely associated with systemic lupus erythematosus. In the central nervous system PML demyelinating lesions occur in the supratentorial compartment. The authors describe a rare case of PML secondary to SLE treatment with atypical presentation restricted to the posterior fossa (author)

Heavy-ion interactions of deformed nuclei. Progress report and final report, January 1, 1985-December 31, 1985

International Nuclear Information System (INIS)

Oberacker, V.E.

1985-09-01

This Progress Report describes the main topics that were investigated during the reporting period: (1) a new microscopic approach (many-body theory with two-center shell model basis) to the calculation of heavy-ion interaction potentials, primarily for heavy systems; (2) dynamic alignment of deformed nuclei during heavy-ion collisions; (3) the role of shell effects, static deformation and dynamic alignment in heavy-ion fusion reactions; (4) giant nuclear quasimolecules and the positron problem. The proposed research has direct relevance to experimental programs supported by DOE, e.g. the Holifield Heavy-Ion Research Facility (HHIRF) at Oak Ridge, the ATLAS accelerator at Argonne National Laboratory, the Double MP Tandem at Brookhaven and some of the smaller University-based accelerators. A discussion of a review article on Coulomb fission is presented. 36 refs., 7 figs

Operational experience with optical matching in the SLC Final Focus System

International Nuclear Information System (INIS)

Bambade, P.; Burchat, P.; Burke, D.

1989-01-01

In the SLC Final Focus System, all components of transverse phase-space and the couplings between them must be controlled to minimize the beam size at the interaction point. After summarizing the experimental algorithm and the on-line tuning programs, we present a consistent set of measurements and describe our present understanding of the various contributions to this beam size. 17 refs., 9 figs

Comparative efficiency of final endodontic cleansing procedures in removing a radioactive albumin from root canal systems

International Nuclear Information System (INIS)

Cecic, P.A.; Peters, D.D.; Grower, M.F.

1984-01-01

Fifty-six teeth were initially instrumented, with the use of seven irrigants or irrigant combinations, and filled with radioactive albumin. The study then showed the relative ability of three final endodontic procedures (copious reirrigation with saline solution, drying with paper points, and reassuring patency of the canal with the final instrument) to remove the albumin. Even after copious irrigation, each additional procedure removed statistically significant amounts of albumin. Alternating an organic solvent and an inorganic solvent did appear to leave the canal system in the optimal condition for final cleansing procedures. The study then correlated the relative efficiency of irrigation alone versus instrumentation plus irrigation in removing the remaining albumin from the canal systems. Reinstrumentation plus copious irrigation removed significantly more albumin than copious irrigation alone

Interim evaluation report of the mutually operable database systems by different computers; Denshi keisanki sogo un'yo database system chukan hyoka hokokusho

Energy Technology Data Exchange (ETDEWEB)

NONE

1989-03-01

This is the interim report on evaluation of the mutually operable database systems by different computers. The techniques for these systems fall into four categories of those related to (1) dispersed data systems, (2) multimedia, (3) high reliability, and (4) elementary techniques for mutually operable network systems. The techniques for the category (1) include those for vertically dispersed databases, database systems for multiple addresses in a wide area, and open type combined database systems, which have been in progress generally as planned. Those for the category (2) include the techniques for color document inputting and information retrieval, meaning compiling, understanding highly overlapping data, and controlling data centered by drawings, which have been in progress generally as planned. Those for the category (3) include the techniques for improving resistance of the networks to obstruction, and security of the data in the networks, which have been in progress generally as planned. Those for the category (4) include the techniques for rule processing for development of protocols, protocols for mutually connecting the systems, and high-speed, high-function networks, which have been in progress generally as planned. It is expected that the original objectives are finally achieved, because the development programs for these categories have been in progress generally as planned. (NEDO)

Predicting progress in Picture Exchange Communication System (PECS) use by children with autism.

Science.gov (United States)

Pasco, Greg; Tohill, Christina

2011-01-01

The Picture Exchange Communication System (PECS) is a widely used communication intervention for non-verbal children with autism spectrum disorder. Findings for the benefits of PECS have almost universally been positive, although there is very limited information about the characteristics of PECS users that determine the amount of progress that they are likely to make. To explore the utility of using children's developmental age to predict the subsequent degree of progress using PECS. In a retrospective study, 23 non-verbal 5- and 6-year-old children with autism spectrum disorder attending a special school were assessed to determine their highest level of PECS ability. They were then allocated to one of two groups depending on whether or not they had mastered PECS phase III. All participants had been assessed using the Psycho-Educational Profile-Revised (PEP-R) on entry to the school and before being introduced to PECS. Total developmental age scores were examined to determine whether they accurately predicted membership of the two PECS ability groups. All the 16 children who had mastered PECS phase III had total developmental age scores of 16 months or above, whilst six of the seven children who had not progressed beyond phase III scored below 16 months--the other child had a score of 16 months. The assessment of the developmental level of potential PECS users may provide valuable predictive information for speech-and-language therapists and other professionals in relation to the likely degree of progress and in setting realistic and achievable targets. © 2010 Royal College of Speech & Language Therapists.

Improved methods for water shutoff. Final technical progress report, October 1, 1997--September 30, 1998

Energy Technology Data Exchange (ETDEWEB)

Seright, R.S.; Liang, J.T.; Schrader, R.; Hagstrom, J. II; Liu, J.; Wavrik, K.

1998-10-01

In the United States, more than 20 billion barrels of salt water are produced each year during oilfield operations. A tremendous economic incentive exists to reduce water production if that can be accomplished without significantly sacrificing hydrocarbon production. This three-year research project had three objectives. The first objective was to identify chemical blocking agents that will (a) during placement, flow readily through fractures without penetrating significantly into porous rock and with screening out or developing excessive pressure gradients and (b) at a predictable and controllable time, become immobile and resistant breakdown upon exposure to moderate to high pressure gradients. The second objective was to identify schemes that optimize placement of the above blocking agents. The third objective was to explain why gels and other chemical blocking agents reduce permeability to one phase (e.g., water) more than that to another phase (e.g., oil or gas). The authors also wanted to identify conditions that maximize this phenomenon. This project consisted of three tasks, each of which addressed one of the above objectives. This report describes work performed during the third and final period of the project. During this three-year project, they: (1) Developed a procedure and software for sizing gelant treatments in hydraulically fractured production wells; (2) Developed a method (based on interwell tracer results) to determine the potential for applying gel treatments in naturally fractured reservoirs; (3) Characterized gel properties during extrusion through fractures; (4) Developed a method to predict gel placement in naturally fractured reservoirs; (5) Made progress in elucidating the mechanism for why some gels can reduce permeability to water more than that to oil; (6) Demonstrated the limitations of using water/oil ratio diagnostic plots to distinguish between channeling and coning; and (7) Proposed a philosophy for diagnosing and attacking water

A Multimedia Tutorial for Charged-Particle Beam Dynamics. Final report

International Nuclear Information System (INIS)

Silbar, Richard R.

1999-01-01

In September 1995 WhistleSoft, Inc., began developing a computer-based multimedia tutorial for charged-particle beam dynamics under Phase II of a Small Business Innovative Research grant from the U.S. Department of Energy. In Phase I of this project (see its Final Report) we had developed several prototype multimedia modules using an authoring system on NeXTStep computers. Such a platform was never our intended target, and when we began Phase II we decided to make the change immediately to develop our tutorial modules for the Windows and Macintosh microcomputer market. This Report details our progress and accomplishments. It also gives a flavor of the look and feel of the presently available and upcoming modules

A Multimedia Tutorial for Charged-Particle Beam Dynamics. Final report

Energy Technology Data Exchange (ETDEWEB)

Silbar, Richard R.

1999-07-26

In September 1995 WhistleSoft, Inc., began developing a computer-based multimedia tutorial for charged-particle beam dynamics under Phase II of a Small Business Innovative Research grant from the U.S. Department of Energy. In Phase I of this project (see its Final Report) we had developed several prototype multimedia modules using an authoring system on NeXTStep computers. Such a platform was never our intended target, and when we began Phase II we decided to make the change immediately to develop our tutorial modules for the Windows and Macintosh microcomputer market. This Report details our progress and accomplishments. It also gives a flavor of the look and feel of the presently available and upcoming modules.

Merit-Based Incentive Payment System: Meaningful Changes in the Final Rule Brings Cautious Optimism.

Science.gov (United States)

Manchikanti, Laxmaiah; Helm Ii, Standiford; Calodney, Aaron K; Hirsch, Joshua A

2017-01-01

The Medicare Access and CHIP Reauthorization Act of 2015 (MACRA) eliminated the flawed Sustainable Growth Rate (SGR) act formula - a longstanding crucial issue of concern for health care providers and Medicare beneficiaries. MACRA also included a quality improvement program entitled, "The Merit-Based Incentive Payment System, or MIPS." The proposed rule of MIPS sought to streamline existing federal quality efforts and therefore linked 4 distinct programs into one. Three existing programs, meaningful use (MU), Physician Quality Reporting System (PQRS), value-based payment (VBP) system were merged with the addition of Clinical Improvement Activity category. The proposed rule also changed the name of MU to Advancing Care Information, or ACI. ACI contributes to 25% of composite score of the four programs, PQRS contributes 50% of the composite score, while VBP system, which deals with resource use or cost, contributes to 10% of the composite score. The newest category, Improvement Activities or IA, contributes 15% to the composite score. The proposed rule also created what it called a design incentive that drives movement to delivery system reform principles with the inclusion of Advanced Alternative Payment Models (APMs).Following the release of the proposed rule, the medical community, as well as Congress, provided substantial input to Centers for Medicare and Medicaid Services (CMS),expressing their concern. American Society of Interventional Pain Physicians (ASIPP) focused on 3 important aspects: delay the implementation, provide a 3-month performance period, and provide ability to submit meaningful quality measures in a timely and economic manner. The final rule accepted many of the comments from various organizations, including several of those specifically emphasized by ASIPP, with acceptance of 3-month reporting period, as well as the ability to submit non-MIPS measures to improve real quality and make the system meaningful. CMS also provided a mechanism for

An assessment of the impact of trauma systems consultation on the level of trauma system development.

Science.gov (United States)

Winchell, Robert J; Ball, Jane W; Cooper, Gail F; Sanddal, Nels D; Rotondo, Michael F

2008-11-01

Studies have shown that trauma systems decrease morbidity and mortality after injury. Despite these findings, overall progress in system development has been slow and inconsistent. The American College of Surgeons Committee on Trauma (COT) has developed a process to provide expert consultation to facilitate regional trauma system development. This study evaluated the progress that occurred after COT consultation visits in six regional systems. All six trauma systems undergoing COT consultation between January 1, 2004 and September 1, 2006 were included in the study. Using a set of 16 objective indicators, preconsultation status was retrospectively assessed by members of the original consultation team using data from the final consultation reports. Postconsultation status was assessed by directed telephone conference, conducted by members of the original consultation team with current key representatives from each system. Progress was assessed by comparing changes in both aggregate and individual indicator scores. This study showed a statistically significant increase in aggregate indicator scores after consultation. The largest gains were seen in systems with the longest time interval between the two assessments. Individual indicators related to system planning and quality assurance infrastructure showed the most improvement. Little or no change was seen in indicators related to system funding. The COT consultation process appears to be effective in facilitating regional trauma system development. In this short-term followup study, progress was seen primarily in areas related to planning and system design. Consultation was not effective in helping systems secure stable funding.

Uranium reactions with water vapor. Final progress report

International Nuclear Information System (INIS)

Condon, J.B.; Cristy, S.S.; Kirkpatrick, J.R.

1983-01-01

The reaction kinetics and ion microprobe mass analyzer (IMMA) depth-profile data for water-oxygen-uranium reaction is explained in terms of the perfusive-precipitation model. This model is reviewed extensively enough to deal with this interacting, 3-element reaction system. The model, based on simultaneous diffusion and product precipitation, can be applied to several systems in a parameterless fashion. It is applied to the uranium-water reaction in the absence and presence of the oxygen inhibitor. The results of the calculations of the model are compared to the experimental rates and the IMMA depth profiles obtained when 18 O-labeled water is used. The predictions are excellent for the pressure dependence of the rates, the activation energies for both the oxygen-poisoned and oxygen-free reactions, the absolute rates for the oxygen-poisoned case, and the IMMA depth profiles. The prediction of the absolute rate for the oxygen-free case is only within a factor of five due to the approximations made for the thermodynamics of the product layer that fixes the oxygen activity. Comparison of the model to experimental data for other metal-oxidation systems such as iron, silicon, copper, zirconium with oxygen, and thorium with water, is also presented to lend credibility to the modeling technique

Final report for the 'Melt-Vessel Interactions' Project. European Union R and TD Program 4th Framework. MVI project final research report

Energy Technology Data Exchange (ETDEWEB)

Sehgal, B.R.; Dinh, T.N.; Nourgaliev, R.R.; Bui, V.A.; Green, J.; Kolb, G.; Karbojian, A.; Theerthan, S.A.; Gubaidulline, A. [Royal Inst. of Tech., Stockholm (Sweden). Div. of Nuclear Power Safety; Helle, M.; Kymaelaeinen, O.; Tuomisto, H. [IVO Power Engineering Ltd., Vantaa (Finland); Bonnet, J.M.; Rouge, S.; Narcoux, M.; Liegeois, A. [CEA - Grenoble (France); Turland, B.D.; Dobson, G.P. [AEA Technology plc, Dorchester (United Kingdom); Siccama, A. [ECN Nuclear Research, Petten (Netherlands); Ikonen, K. [VTT Energy, Helsinki (Finland); Parozzi, F. [ENEL - SRI/PAM/GRA, Segrate, MI (Italy); Kolev, N. [Siemens AG, Erlangen (Germany); Caira, M. [Univ. of Roma (Italy)

1999-04-01

The Melt Vessel Interaction (MVI) project is concerned with the consequences of the interactions that a core melt, generated during a postulated severe accident in a light water reactor, may have with the pressure vessel. In particular, the issues concerned with the failure of the vessel bottom head are the focus of the research. The specific objectives of the project are to obtain data and develop validated models, which could be applied to prototypic plants, and accident conditions, for resolution of issues related to the melt vessel interactions. The project work has been performed by nine partners having varied responsibility. The work included a large number of experiments, with simulant materials, whose observations and results are employed, respectively, to understand the physical mechanisms and to develop validated models. Applications to the prototypic geometry and conditions have also been performed. This report is volume 1 of the Final Report for the Project, in which a summary of the progress achieved in the experimental program is provided. We have, however, included some aspects of the modeling activities. Volume 2 of the Final report describes the progress achieved in the modeling program. The progress achieved in the experimental and modeling parts of the Project has led to the resolution of some of the issues of melt vessel interaction. Considerable progress was also achieved towards resolution of the remaining issues.

Progress Check Module; Basic Electricity and Electronics Individualized Learning System. Progress Check Booklet.

Science.gov (United States)

Bureau of Naval Personnel, Washington, DC.

The Progress Check Booklet is designed to be used by the student working in the programed course to determine if he has mastered the concepts in the course booklets on: electrical current; voltage; resistance; measuring current and voltage in series circuits; relationships of current, voltage, and resistance; parellel circuits; combination…

Positron ring system using anger-type detectors. Progress report, January 1-December 31, 1986

International Nuclear Information System (INIS)

Muehllehner, G.

1986-09-01

The design of a new multislice system consisting of six position-sensitive area detectors has been completed, and the system is now in the final assembly phase. This system will be able to reconstruct a volume 50 cm in diameter and 10 cm long with equal resolution of 4 to 5 mm in all directions. The system achieves high sensitivity through a large acceptance angle which is made possible through the use of three-dimensional reconstruction algorithms

Progress in EEG-Based Brain Robot Interaction Systems

Directory of Open Access Journals (Sweden)

Xiaoqian Mao

2017-01-01

Full Text Available The most popular noninvasive Brain Robot Interaction (BRI technology uses the electroencephalogram- (EEG- based Brain Computer Interface (BCI, to serve as an additional communication channel, for robot control via brainwaves. This technology is promising for elderly or disabled patient assistance with daily life. The key issue of a BRI system is to identify human mental activities, by decoding brainwaves, acquired with an EEG device. Compared with other BCI applications, such as word speller, the development of these applications may be more challenging since control of robot systems via brainwaves must consider surrounding environment feedback in real-time, robot mechanical kinematics, and dynamics, as well as robot control architecture and behavior. This article reviews the major techniques needed for developing BRI systems. In this review article, we first briefly introduce the background and development of mind-controlled robot technologies. Second, we discuss the EEG-based brain signal models with respect to generating principles, evoking mechanisms, and experimental paradigms. Subsequently, we review in detail commonly used methods for decoding brain signals, namely, preprocessing, feature extraction, and feature classification, and summarize several typical application examples. Next, we describe a few BRI applications, including wheelchairs, manipulators, drones, and humanoid robots with respect to synchronous and asynchronous BCI-based techniques. Finally, we address some existing problems and challenges with future BRI techniques.

Progress report of the CEC project Rodos system development. Period: 1 september 92-31 august 93

International Nuclear Information System (INIS)

Marchand, O.

1994-01-01

Within the context of the Radioprotection program of the CEC, the RODOS project (Real-time On-line DecisiOn Support system) aims at the development of a decision support system for nuclear emergencies. RODOS involves 22 research teams, divided in 4 sub-projects: 'Meteorology and Atmospheric Dispersion, 'System Development', 'Decision Aiding Techniques'. The fourth sub-project is a Joint Study Project of the Agreement between CEC ad the CIS republics. EDF is working in the 'System Development' sub-project and namely in the 'training' group. This group aims at the creation of a specific training course for health physics managers, based on RODOS. This note reproduces the progress report of the 'Development System' project. The reporting period is: September 92 - August 93. Progress bas been made within the reporting period in the: - development of data assimilation methods incorporating both monitoring data and model predictions for obtaining consistent pictures of the environmental contamination and the source term ; - improvement and extension of the modules ATSTEP-CORA (atmospheric dispersion and deposition), EMERSIM (simulation of emergency actions), ECOAMOR (exposure pathways and dose calculation) and FRODO (simulation of relocation and agricultural countermeasures) ; - preparation of training courses using RODOS as illustrative tool ; - extension of the functions of the RODOS operating system OSY, in particular of RoGIS, its geographical information system. (author). 2 figs

Interim evaluation report of the mutually operable database systems by different computers; Denshi keisanki sogo un'yo database system chukan hyoka hokokusho

Energy Technology Data Exchange (ETDEWEB)

NONE

1989-03-01

This is the interim report on evaluation of the mutually operable database systems by different computers. The techniques for these systems fall into four categories of those related to (1) dispersed data systems, (2) multimedia, (3) high reliability, and (4) elementary techniques for mutually operable network systems. The techniques for the category (1) include those for vertically dispersed databases, database systems for multiple addresses in a wide area, and open type combined database systems, which have been in progress generally as planned. Those for the category (2) include the techniques for color document inputting and information retrieval, meaning compiling, understanding highly overlapping data, and controlling data centered by drawings, which have been in progress generally as planned. Those for the category (3) include the techniques for improving resistance of the networks to obstruction, and security of the data in the networks, which have been in progress generally as planned. Those for the category (4) include the techniques for rule processing for development of protocols, protocols for mutually connecting the systems, and high-speed, high-function networks, which have been in progress generally as planned. It is expected that the original objectives are finally achieved, because the development programs for these categories have been in progress generally as planned. (NEDO)

Orion Absolute Navigation System Progress and Challenges

Science.gov (United States)

Holt, Greg N.; D'Souza, Christopher

2011-01-01

The Orion spacecraft is being designed as NASA's next-generation exploration vehicle for crewed missions beyond Low-Earth Orbit. The navigation system for the Orion spacecraft is being designed in a Multi-Organizational Design Environment (MODE) team including contractor and NASA personnel. The system uses an Extended Kalman Filter to process measurements and determine the state. The design of the navigation system has undergone several iterations and modifications since its inception, and continues as a work-in-progress. This paper seeks to benchmark the current state of the design and some of the rationale and analysis behind it. There are specific challenges to address when preparing a timely and effective design for the Exploration Flight Test (EFT-1), while still looking ahead and providing software extensibility for future exploration missions. The primary measurements in a Near-Earth or Mid-Earth environment consist of GPS pseudorange and deltarange, but for future explorations missions the use of star-tracker and optical navigation sources need to be considered. Discussions are presented for state size and composition, processing techniques, and consider states. A presentation is given for the processing technique using the computationally stable and robust UDU formulation with an Agee-Turner Rank-One update. This allows for computational savings when dealing with many parameters which are modeled as slowly varying Gauss-Markov processes. Preliminary analysis shows up to a 50% reduction in computation versus a more traditional formulation. Several state elements are discussed and evaluated, including position, velocity, attitude, clock bias/drift, and GPS measurement biases in addition to bias, scale factor, misalignment, and non-orthogonalities of the accelerometers and gyroscopes. Another consideration is the initialization of the EKF in various scenarios. Scenarios such as single-event upset, ground command, pad alignment, cold start are discussed as are

48 CFR 2052.211-71 - Technical progress report.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Technical progress report... Technical progress report. As prescribed at 2011.104-70(b), the contracting officer shall insert the... solicitation. Technical Progress Report (JAN 1993) The contractor shall provide a monthly Technical Progress...

In vessel core melt progression phenomena

International Nuclear Information System (INIS)

Courtaud, M.

1993-01-01

For all light water reactor (LWR) accidents, including the so called severe accidents where core melt down can occur, it is necessary to determine the amount and characteristics of fission products released to the environment. For existing reactors this knowledge is used to evaluate the consequences and eventual emergency plans. But for future reactors safety authorities demand decrease risks and reactors designed in such a way that fission products are retained inside the containment, the last protective barrier. This requires improved understanding and knowledge of all accident sequences. In particular it is necessary to be able to describe the very complex phenomena occurring during in vessel core melt progression because they will determine the thermal and mechanical loads on the primary circuit and the timing of its rupture as well as the fission product source term. On the other hand, in case of vessel failure, knowledge of the physical and chemical state of the core melt will provide the initial conditions for analysis of ex-vessel core melt progression and phenomena threatening the containment. Finally a good understanding of in vessel phenomena will help to improve accident management procedures like Emergency Core Cooling System water injection, blowdown and flooding of the vessel well, with their possible adverse effects. Research and Development work on this subject was initiated a long time ago and is still in progress but now it must be intensified in order to meet the safety requirements of the next generation of reactors. Experiments, limited in scale, analysis of the TMI 2 accident which is a unique source of global information and engineering judgment are used to establish and assess physical models that can be implemented in computer codes for reactor accident analysis

Progress in Childhood Vaccination Data in Immunization Information Systems - United States, 2013-2016.

Science.gov (United States)

Murthy, Neil; Rodgers, Loren; Pabst, Laura; Fiebelkorn, Amy Parker; Ng, Terence

2017-11-03

In 2016, 55 jurisdictions in 49 states and six cities in the United States* used immunization information systems (IISs) to collect and manage immunization data and support vaccination providers and immunization programs. To monitor progress toward achieving IIS program goals, CDC surveys jurisdictions through an annual self-administered IIS Annual Report (IISAR). Data from the 2013-2016 IISARs were analyzed to assess progress made in four priority areas: 1) data completeness, 2) bidirectional exchange of data with electronic health record systems, 3) clinical decision support for immunizations, and 4) ability to generate childhood vaccination coverage estimates. IIS participation among children aged 4 months through 5 years increased from 90% in 2013 to 94% in 2016, and 33 jurisdictions reported ≥95% of children aged 4 months through 5 years participating in their IIS in 2016. Bidirectional messaging capacity in IISs increased from 25 jurisdictions in 2013 to 37 in 2016. In 2016, nearly all jurisdictions (52 of 55) could provide automated provider-level coverage reports, and 32 jurisdictions reported that their IISs could send vaccine forecasts to providers via Health Level 7 (HL7) messaging, up from 17 in 2013. Incremental progress was made in each area since 2013, but continued effort is needed to implement these critical functionalities among all IISs. Success in these priority areas, as defined by the IIS Functional Standards (1), bolsters clinicians' and public health practitioners' ability to attain high vaccination coverage in pediatric populations, and prepares IISs to develop more advanced functionalities to support state/local immunization services. Success in these priority areas also supports the achievement of federal immunization objectives, including the use of IISs as supplemental sampling frames for vaccination coverage surveys like the National Immunization Survey (NIS)-Child, reducing data collection costs, and supporting increased precision

Progress in application of hybrid numerical simulation methods to magnetic confinement systems. Annual report

International Nuclear Information System (INIS)

Morse, R.L.

1979-06-01

Hybrid codes have been developed to simulate high density, high β confined plasmas. The major areas of application have been end plugging and heating of linear confinement systems. In particular, significant progress has been made in understanding the role of line and recombination radiation in recent experiments which showed large increases in energy confinement times from the use of solid end plugs. Another accomplishment is the conception and theoretical analysis of an efficient, low frequency, axial heating method which we believe could significantly increase the attractiveness of linear systems as reactors

Comment Response on the Final Report: Peer Review of the Total System Performance Assessment-Viability Assessment (TSPA-VA)

International Nuclear Information System (INIS)

Pendleton, M. W.

1999-01-01

The Management and Operating Contractor established a Performance Assessment Peer Review Panel (hereinafter ''the Panel'') at the request of the U.S. Department of Energy Yucca Mountain Site Characterization Office. The objectives of the peer review were to provide: (1) A formal, independent evaluation and critique of Viability Assessment of a Repository at Yucca Mountain: Total System Performance Assessment, Volume 3 (DOE 1998a; hereinafter ''Total System Performance Assessment-Viability Assessment'') that was conducted in support of the Viability Assessment of a Repository at Yucca Mountain (DOE 1998b). (2) Suggestions for improvements as the U.S. Department of Energy prepares to develop the documentation for a Total System Performance Assessment to support a potential License Application. The Panel conducted a phased review over a two-year period to observe the development and, ultimately, to review the Total System Performance Assessment-Viability Assessment (DOE 1998a). During the development of the Total System Performance Assessment-Viability Assessment (DOE 1998a), the Panel submitted three Interim Reports (Whipple et al., 1997a, 1997b, and 1998) to the Management and Operating Contractor with recommendations and comments on the process models, model abstractions, and draft documentation for the Total System Performance Assessment-Viability Assessment (DOE 1998a). The Panel's Final Report Total System Performance Assessment Peer Review Panel (Whipple et al. 1999; hereinafter ''Final Report'') on the Total System Performance Assessment-Viability Assessment (DOE 1998a) is based primarily on the completed Total System Performance Assessment-Viability Assessment (DOE 1998a), the Total System Performance Assessment-Viability Assessment (TSPA-VA) Analyses Technical Basis Document (CRWMS M and O 1998), and the cited references. The Final Report (Whipple et al. 1999) includes the major points from the three Interim Reports (Whipple et al. 1997a, 1997b, and 1998

Radiation chemistry of hydrocarbon and alkyl halide systems. Progress report, August 1, 1977--August 1, 1978

International Nuclear Information System (INIS)

Hanrahan, R.J.

1978-01-01

Progress of experimental work is reported on pulse radiolysis of simple alkyl halides in the gas phase, gas phase radiolysis of CHF 3 -CH 3 I mixtures, gamma radiolysis of the system CO/H 2 , and improvements in equipment and facilities

Studies of heavy fermion systems: Progress report, July 1, 1986-December 31, 1988

International Nuclear Information System (INIS)

Stewart, G.R.

1988-01-01

Major projects put forward in the original proposal were: radiation damage studies of the heavy fermion superconductors UBe 13 and UPt 3 ; chemical substitution experiments, including CeCu/sub 6-x/M/sub x/; high magnetic field specific heat measurements; search for new heavy fermion systems (HFS). A summary of results on these projects will be discussed first, followed by additional work done during the contract period - some of which is still in progress

Radiation Hardened Telerobotic Dismantling System Development Final Report CRADA No. TC-1340-96

Energy Technology Data Exchange (ETDEWEB)

Smith, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Lightman, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2017-09-27

This project was a collaborative effort between the University of California, LLNL and RedZone Robotics, Inc. for the development of radiation-hardened telerobotic dismantling systems for use in applications such as nuclear facility remediation, nuclear accident response, and Chemobyltype remediation. The project supported the design, development, fabrication and testing of a Ukrainian robotic systems. The project was completed on time and within budget. All deliverables were completed. The final project deliverables were consistent with the plans developed in the original project with the exception that the fabricated systems remained in Ukraine.

SOFC/TEG hybrid mCHP system. Final report

Energy Technology Data Exchange (ETDEWEB)

2012-03-15

The starting point for this project have been the challenge has been to develop a cost effective solution with long term stability. This is where a focused effort in a strong consortium covering material research, module development and manufacture as well as device design and optimization can make a real difference. In March 2010 the SOFTEG phase II project was initiated and a cooperation organization was established to implement the project as a development and demonstration project involving the staff from all project partners. The project is now completed with excellent and documented outcome. The final results by Alpcon have been demonstration as a TEG-based mCHP system calls CHP Dual Engine Power System, which will be applicable as both a standalone TEG-CHP hybrid system, but also as an auxiliary power unit and power booster for the SOFC system. However the SOFC system cannot cover the household's heat demand alone so it is necessary to combine a SOFC system together with a water heater/boiler system to cover the peak heat demand of a residential house or a complex building. The SOFTEG project partners achieved significant results that mainly can be outlined as following: 1) University of Aarhus has improved the thermal stability of ZnSb by optimizing the concentration of Nano composite material. 2) The grain size and its influence on the sintering process by spark plasma method are investigated by Aarhus University, but further work seems to be necessary. 3) The TE material is going to commercialization by Aarhus University. 4) Aalborg University has prepared simulation tools for complex thermoelectric simulation in non-steady state condition. 5) The new type DCDC interleaved converter using the MPPT system for optimal power tracing is designed, build and tested by Aalborg University in cooperation with Alpcon. This task is included overall system design, control system implementation and power electronic control design. 6) Full scale practical

Annual progress report

International Nuclear Information System (INIS)

Russek, A.

1975-06-01

Progress has been made in calculation of cross-sections for dielectronic and radiative recombination when hot electrons are incident on partially stripped impurity ions. Calculations were completed for the cases of 1 keV and 10 keV electrons incident on ions of arbitrary Z with ionization state consistent with a 1 keV plasma temperature. It was found that dielectronic recombination dominates radiative recombination by a factor of 100 at 1 keV incident electron energy to a factor of 1000 at 10 keV incident electron energy. The work is now being extended to other plasma temperatures and is being improved by more accurate calculation of the matrix elements involved. Progress was also made in the calculation of accurate bremsstrahlung and higher order radiative processes which also occur when hot electrons are incident on partially stripped impurity ions. Formal expressions for the matrix elements have been obtained for cross-sections in a fully relativistic partial wave analysis for bremsstrahlung radiation both with and without electron excitation of the target ion. Final evaluation now awaits the evaluation of the relativistic radial integrals involved in these matrix elements. (U.S.)

Therapeutic advances in multiple system atrophy and progressive supranuclear palsy.

Science.gov (United States)

Poewe, Werner; Mahlknecht, Philipp; Krismer, Florian

2015-09-15

Multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) are relentlessly progressive neurodegenerative diseases leading to severe disability and ultimately death within less than 10 y. Despite increasing efforts in basic and clinical research, effective therapies for these atypical parkinsonian disorders are lacking. Although earlier small clinical studies in MSA and PSP mainly focused on symptomatic treatment, advances in the understanding of the molecular underpinnings of these diseases and in the search for biomarkers have paved the way for the first large and well-designed clinical trials aiming at disease modification. Targets of intervention in these trials have included α-synuclein inclusion pathology in the case of MSA and tau-related mechanisms in PSP. Since 2013, four large randomized, placebo-controlled, double-blind disease-modification trials have been completed and published, using rasagiline (MSA), rifampicin (MSA), tideglusib (PSP), or davunetide (PSP). All of these failed to demonstrate signal efficacy with regard to the primary outcome measures. In addition, two randomized, placebo-controlled, double-blind trials have studied the efficacy of droxidopa in the symptomatic treatment of neurogenic orthostatic hypotension, including patients with MSA, with positive results in one trial. This review summarizes the design and the outcomes of these and other smaller trials published since 2013 and attempts to highlight priority areas of future therapeutic research in MSA and PSP. © 2015 International Parkinson and Movement Disorder Society. © 2015 International Parkinson and Movement Disorder Society.

Expanded studies of linear collider final focus systems at the Final Focus Test Beam

International Nuclear Information System (INIS)

Tenenbaum, P.G.

1995-12-01

In order to meet their luminosity goals, linear colliders operating in the center-of-mass energy range from 3,50 to 1,500 GeV will need to deliver beams which are as small as a few Manometers tall, with x:y aspect ratios as large as 100. The Final Focus Test Beam (FFTB) is a prototype for the final focus demanded by these colliders: its purpose is to provide demagnification equivalent to those in the future linear collider, which corresponds to a focused spot size in the FFTB of 1.7 microns (horizontal) by 60 manometers (vertical). In order to achieve the desired spot sizes, the FFTB beam optics must be tuned to eliminate aberrations and other errors, and to ensure that the optics conform to the desired final conditions and the measured initial conditions of the beam. Using a combination of incoming-beam diagnostics. beam-based local diagnostics, and global tuning algorithms, the FFTB beam size has been reduced to a stable final size of 1.7 microns by 70 manometers. In addition, the chromatic properties of the FFTB have been studied using two techniques and found to be acceptable. Descriptions of the hardware and techniques used in these studies are presented, along with results and suggestions for future research

Expanded studies of linear collider final focus systems at the Final Focus Test Beam

Energy Technology Data Exchange (ETDEWEB)

Tenenbaum, Peter Gregory [Stanford Univ., CA (United States)

1995-12-01

In order to meet their luminosity goals, linear colliders operating in the center-of-mass energy range from 3,50 to 1,500 GeV will need to deliver beams which are as small as a few Manometers tall, with x:y aspect ratios as large as 100. The Final Focus Test Beam (FFTB) is a prototype for the final focus demanded by these colliders: its purpose is to provide demagnification equivalent to those in the future linear collider, which corresponds to a focused spot size in the FFTB of 1.7 microns (horizontal) by 60 manometers (vertical). In order to achieve the desired spot sizes, the FFTB beam optics must be tuned to eliminate aberrations and other errors, and to ensure that the optics conform to the desired final conditions and the measured initial conditions of the beam. Using a combination of incoming-beam diagnostics. beam-based local diagnostics, and global tuning algorithms, the FFTB beam size has been reduced to a stable final size of 1.7 microns by 70 manometers. In addition, the chromatic properties of the FFTB have been studied using two techniques and found to be acceptable. Descriptions of the hardware and techniques used in these studies are presented, along with results and suggestions for future research.

Columbia River system operation review. Final environmental impact statement. Appendix J, recreation

International Nuclear Information System (INIS)

1995-11-01

This Appendix J of the Final Environmental Impact Statement for the Columbia River System discusses impacts on the recreational activities in the region. Major sections include the following: scope and processes; recreation in the Columbia River Basin today - by type, location, participation, user characteristics, factors which affect usage, and managing agencies; recreation analysis procedures and methodology; and alternatives and their impacts

Columbia River System Operation Review : Final Environmental Impact Statement, Appendix J: Recreation.

Energy Technology Data Exchange (ETDEWEB)

Columbia River System Operation Review (U.S.)

1995-11-01

This Appendix J of the Final Environmental Impact Statement for the Columbia River System discusses impacts on the recreational activities in the region. Major sections include the following: scope and processes; recreation in the Columbia River Basin today - by type, location, participation, user characteristics, factors which affect usage, and managing agencies; recreation analysis procedures and methodology; and alternatives and their impacts.

Measuring and reporting on decommissioning progress

International Nuclear Information System (INIS)

Lange, B.A.

2006-01-01

One of the challenges facing AECL, as well as other organizations charged with the responsibility of decommissioning nuclear facilities, is the means by which to measure and report on decommissioning progress to various audiences which, in some cases, may only have a peripheral knowledge or understanding of the complexities associated with the decommissioning process. The reporting and measurement of decommissioning progress is important for a number of reasons, i.e., It provides a vehicle by which to effectively communicate the nature of the decommissioning process; It ensures that stakeholders and shareholders are provided with a transparent and understandable means for assessing value for money; It provides a means by which to integrate the planning, measurement, and operational aspects of decommissioning One underlying reason behind the challenge of reporting decommissioning progress lies in the fact that decommissioning programs are generally executed over periods of time that far exceed those generally associated with typical design and build projects. For example, a decommissioning program could take decades to complete in which case progress on the order of a few percent in any one year might be typical. However, such progress may appear low compared to that seen with more typical projects that can be completed in a matter of years. As a consequence, AECL undertook to develop a system by which to measure decommissioning progress in a straightforward, meaningful, and understandable fashion. The system is not rigorously objective, and there are subjective aspects that are necessitated by the need to keep the system readily understandable. It is also important to note that while the system is simple in concept, there is, nonetheless, significant effort involved in generating and updating the parameters used as input, and in the actual calculations. (author)

Columbia River System Operation Review : Final Environmental Impact Statement, Main Report Exhibits.

Energy Technology Data Exchange (ETDEWEB)

Columbia River System Operation Review (U.S.)

1995-11-01

This Volume is a part of the Final Environmental Impact Statement (EIS) for the Columbia River System. This volume contains technical exhibits of cultural resources and commentary on the (System Operation Review) SOR process. The Confederated Tribes of the Umatilla Indian Reservation comment is the majority of the material in the volume, in the Consultation Plan, Identification of trust resources; Criteria for the selection of a System Operating Strategy; comment on rights protection and implementation of Federal Trust responsibility; analysis of the draft EIS. Comment by other Native American Tribes and groups is also included: Confederated Tribes of the Colville Reservation; Kootenai Tribe of Idaho; Spokane Tribe of Indians; Coeur d` Alene tribe.

Columbia River system operation review: Final environmental impact statement. Main report exhibits

International Nuclear Information System (INIS)

1995-11-01

This Volume is a part of the Final Environmental Impact Statement (EIS) for the Columbia River System. This volume contains technical exhibits of cultural resources and commentary on the (System Operation Review) SOR process. The Confederated Tribes of the Umatilla Indian Reservation comment is the majority of the material in the volume, in the Consultation Plan, Identification of trust resources; Criteria for the selection of a System Operating Strategy; comment on rights protection and implementation of Federal Trust responsibility; analysis of the draft EIS. Comment by other Native American Tribes and groups is also included: Confederated Tribes of the Colville Reservation; Kootenai Tribe of Idaho; Spokane Tribe of Indians; Coeur d' Alene tribe

Final design of a free-piston hydraulic advanced Stirling conversion system

Science.gov (United States)

Wallace, D. A.; Noble, J. E.; Emigh, S. G.; Ross, B. A.; Lehmann, G. A.

1991-01-01

Under the US Department of Energy's (DOEs) Solar Thermal Technology Program, Sandia National Laboratories is evaluating heat engines for solar distributed receiver systems. The final design is described of an engineering prototype advanced Stirling conversion system (ASCS) with a free-piston hydraulic engine output capable of delivering about 25 kW of electric power to a utility grid. The free-piston Stirling engine has the potential for a highly reliable engine with long life because it has only a few moving parts, has noncontacting bearings, and can be hermetically sealed. The ASCS is designed to deliver maximum power per year over a range of solar input with a design life of 30 years (60,000 h). The system includes a liquid Nak pool boiler heat transport system and a free-piston Stirling engine with high-pressure hydraulic output, coupled with a bent axis variable displacement hydraulic motor and a rotary induction generator.

Final design of a free-piston hydraulic advanced Stirling conversion system

Science.gov (United States)

Wallace, D. A.; Noble, J. E.; Emigh, S. G.; Ross, B. A.; Lehmann, G. A.

Under the US Department of Energy's (DOEs) Solar Thermal Technology Program, Sandia National Laboratories is evaluating heat engines for solar distributed receiver systems. The final design is described of an engineering prototype advanced Stirling conversion system (ASCS) with a free-piston hydraulic engine output capable of delivering about 25 kW of electric power to a utility grid. The free-piston Stirling engine has the potential for a highly reliable engine with long life because it has only a few moving parts, has noncontacting bearings, and can be hermetically sealed. The ASCS is designed to deliver maximum power per year over a range of solar input with a design life of 30 years (60,000 h). The system includes a liquid Nak pool boiler heat transport system and a free-piston Stirling engine with high-pressure hydraulic output, coupled with a bent axis variable displacement hydraulic motor and a rotary induction generator.

Progression following neoadjuvant systemic chemotherapy may not be a contraindication to a curative approach for colorectal carcinomatosis.

Science.gov (United States)

Passot, Guillaume; Vaudoyer, Delphine; Cotte, Eddy; You, Benoit; Isaac, Sylvie; Noël Gilly, François; Mohamed, Faheez; Glehen, Olivier

2012-07-01

The objective of this retrospective study was to evaluate the influence of neoadjuvant systemic chemotherapy on patients with colorectal carcinomatosis before a curative procedure. Peritoneal carcinomatosis (PC) from colorectal cancer may be treated with a curative intent by cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). The role of perioperative systemic chemotherapy for this particular metastatic disease remains unclear. One hundred twenty patients with PC from colorectal cancer were consecutively treated by 131 procedures combining CRS with HIPEC. The response to neoadjuvant systemic chemotherapy was assessed on data from previous explorative surgery and/or radiological imaging. Ninety patients (75%) were treated with neoadjuvant systemic chemotherapy in whom 32 (36%) were considered to have responded, 19 (21%) had stable disease, and 19 (21%) developed diseases progression. Response could not be evaluated in 20 patients (22%). On univariate analysis, the use of neoadjuvant systemic chemotherapy had a significant positive prognostic influence (P = 0.042). On multivariate analysis, the completeness of CRS and the use of adjuvant systemic chemotherapy were the only significant prognostic factors (P systemic chemotherapy had no significant prognostic impact with median survival of 31.4 months in patients showing disease progression. In patients with PC from colorectal cancer without extraperitoneal metastases, failure of neoadjuvant systemic chemotherapy should not constitute an absolute contraindication to a curative procedure combining CRS and HIPEC.

Evaluation of quatitative scintigraphic method in diagnosis of esophagic involvement of Progressive Systemic Sclerosis

International Nuclear Information System (INIS)

Von Muehlen, C.A.

1985-01-01

Twenty patients with Progressive Systemic Sclerosis are studied by scintigraphic methodology. The esophageal transit method is used for liquid and solid meals. The results are compared with the ones of a control group, without or not gastrintestinal problems but without autoimmune diasese. 99 sup(m)Tc-sulfurcolloid is used as labelling compound. The studies were done in supine and orthostatical position. (M.A.C.) [pt

Coal to SNG: Technical progress, modeling and system optimization through exergy analysis

International Nuclear Information System (INIS)

Li, Sheng; Ji, Xiaozhou; Zhang, Xiaosong; Gao, Lin; Jin, Hongguang

2014-01-01

Highlights: • Technical progresses of coal to SNG technologies are reported. • The entire coal to SNG system is modeled. • Coupling between SNG production and power generation is investigated. • Breakthrough points for further energy saving are determined. • System performance is optimized based on the first and second laws of thermodynamics. - Abstract: For both energy security and CO 2 emission reduction, synthetic natural gas (SNG) production from coal is an important path to implement clean coal technologies in China. In this paper, an overview of the progress of coal to SNG technologies, including the development of catalysts, reactor designs, synthesis processes, and systems integration, is provided. The coal to SNG system is modeled, the coupling between SNG production and power generation is investigated, the breakthrough points for further energy savings are determined, and the system performance is optimized based on the first and the second laws of thermodynamics. From the viewpoint of the first law of thermodynamics, the energy conversion efficiency of coal to SNG system can reach 59.8%. To reduce the plant auxiliary power, the breakthrough points are the development of low-energy-consumption oxygen production technology and gas purification technology or seeking new oxidants for coal gasification instead of oxygen. From the viewpoint of the second law of thermodynamics, the major exergy destruction in a coal to SNG system occurs in the coal gasification unit, SNG synthesis unit and the raw syngas cooling process. How to reduce the exergy destruction in these units is the key to energy savings and system performance enhancement. The conversion ratio of the first SNG synthesis reactor and the split ratio of the recycle gas are key factors that determine the performance of both the SNG synthesis process and the whole plant. A “turning point” phenomenon is observed: when the split ratio is higher than 0.90, the exergy destruction of the SNG

Progress in the integration of the ITER plant systems in auxiliary buildings

International Nuclear Information System (INIS)

Kotamäki, M.; Cordier, J.-J.; Kuehn, I.; Perrin, J.-L.; Sweeney, S.; Villedary, B.

2016-01-01

Highlights: • Usage of 3D CAD model in ITER configuration management presented. • 3D CAD models efficient in configuration and interface management. • Costly and schedule delaying changes avoided with proper interface management. • ITER buildings construction progressing. - Abstract: The ITER Tokamak machine is located in the center of Tokamak complex buildings consisting of Tokamak, Diagnostic, and Tritium buildings. Around the Tokamak complex there are over 30 auxiliary buildings housing various plant systems serving the Tokamak machine either directly or indirectly. The layout and space allocation of each auxiliary building and plant systems housed by the building are represented in the so-called Configuration Management Models (CMM). These are light 3D CAD models that define the required space envelope and the physical interfaces between the systems and the buildings and in-between the systems. The paper describes the CMM and interface management processes of the ITER auxiliary buildings and plant systems, and discusses the preparations for the plant installation phase. In addition, the current baseline configuration of the ITER plant systems in auxiliary buildings is described together with the recent developments in the configuration of different systems, as well as the current status of the construction of the buildings.

Progress in the integration of the ITER plant systems in auxiliary buildings

Energy Technology Data Exchange (ETDEWEB)

Kotamäki, M., E-mail: miikka.kotamaki@iter.org; Cordier, J.-J.; Kuehn, I.; Perrin, J.-L.; Sweeney, S.; Villedary, B.

2016-11-01

Highlights: • Usage of 3D CAD model in ITER configuration management presented. • 3D CAD models efficient in configuration and interface management. • Costly and schedule delaying changes avoided with proper interface management. • ITER buildings construction progressing. - Abstract: The ITER Tokamak machine is located in the center of Tokamak complex buildings consisting of Tokamak, Diagnostic, and Tritium buildings. Around the Tokamak complex there are over 30 auxiliary buildings housing various plant systems serving the Tokamak machine either directly or indirectly. The layout and space allocation of each auxiliary building and plant systems housed by the building are represented in the so-called Configuration Management Models (CMM). These are light 3D CAD models that define the required space envelope and the physical interfaces between the systems and the buildings and in-between the systems. The paper describes the CMM and interface management processes of the ITER auxiliary buildings and plant systems, and discusses the preparations for the plant installation phase. In addition, the current baseline configuration of the ITER plant systems in auxiliary buildings is described together with the recent developments in the configuration of different systems, as well as the current status of the construction of the buildings.

Coal-fired MHD test progress at the Component Development and Integration Facility

International Nuclear Information System (INIS)

Hart, A.T.; Rivers, T.J.; Alsberg, C.M.; Filius, K.D.

1992-01-01

The Component Development and Integration Facility (CDIF) is a Department of Energy test facility operated by MSE, Inc. In the fall of 1984, a 50-MW t , pressurized, slag rejecting coal-fired combustor (CFC) replaced the oil-fired combustor in the test train. In the spring of 1989, a coal-fired precombustor was added to the test hardware, and current controls were installed in the spring of 1990. In the fall of 1990, the slag rejector was installed. MSE test hardware activities included installing the final workhorse channel and modifying the coalfired combustor by installing improved design and proof-of-concept (POC) test pieces. This paper discusses the involvement of this hardware in test progress during the past year. Testing during the last year emphasized the final workhorse hardware testing. This testing will be discussed. Facility modifications and system upgrades for improved operation and duration testing will be discussed. In addition, this paper will address long-term testing plans

NONLINEAR DYNAMICAL SYSTEMS - Final report

Energy Technology Data Exchange (ETDEWEB)

Philip Holmes

2005-12-31

This document is the final report on the work completed on DE-FG02-95ER25238 since the start of the second renewal period: Jan 1, 2001. It supplements the annual reports submitted in 2001 and 2002. In the renewal proposal I envisaged work in three main areas: Analytical and topological tools for studying flows and maps Low dimensional models of fluid flow Models of animal locomotion and I describe the progess made on each project.

Grid-Competitive Residential and Commercial Fully Automated PV Systems Technology: Final technical Report, August 2011

Energy Technology Data Exchange (ETDEWEB)

Brown, Katie E.; Cousins, Peter; Culligan, Matt; Jonathan Botkin; DeGraaff, David; Bunea, Gabriella; Rose, Douglas; Bourne, Ben; Koehler, Oliver

2011-08-26

Under DOE's Technology Pathway Partnership program, SunPower Corporation developed turn-key, high-efficiency residential and commercial systems that are cost effective. Key program objectives include a reduction in LCOE values to 9-12 cents/kWh and 13-18 cents/kWh respectively for the commercial and residential markets. Target LCOE values for the commercial ground, commercial roof, and residential markets are 10, 11, and 13 cents/kWh. For this effort, SunPower collaborated with a variety of suppliers and partners to complete the tasks below. Subcontractors included: Solaicx, SiGen, Ribbon Technology, Dow Corning, Xantrex, Tigo Energy, and Solar Bridge. SunPower's TPP addressed nearly the complete PV value chain: from ingot growth through system deployment. Throughout the award period of performance, SunPower has made progress toward achieving these reduced costs through the development of 20%+ efficient modules, increased cell efficiency through the understanding of loss mechanisms and improved manufacturing technologies, novel module development, automated design tools and techniques, and reduced system development and installation time. Based on an LCOE assessment using NREL's Solar Advisor Model, SunPower achieved the 2010 target range, as well as progress toward 2015 targets.

IRIS International Reactor Innovative and Secure Final Technical Progress Report

International Nuclear Information System (INIS)

Carelli, M.D.

2003-01-01

OAK-B135 This NERI project, originally started as the Secure Transportable Autonomous Light Water Reactor (STAR-LW) and currently known as the International Reactor Innovative and Secure (IRIS) project, had the objective of investigating a novel type of water-cooled reactor to satisfy the Generation IV goals: fuel cycle sustainability, enhanced reliability and safety, and improved economics. The research objectives over the three-year (1999-2002) program were as follows: First year: Assess various design alternatives and establish main characteristics of a point design; Second year: Perform feasibility and engineering assessment of the selected design solutions; Third year: Complete reactor design and performance evaluation, including cost assessment These objectives were fully attained and actually they served to launch IRIS as a full fledged project for eventual commercial deployment. The program did not terminate in 2002 at the end of the NERI program, and has just entered in its fifth year. This has been made possible by the IRIS project participants which have grown from the original four member, two-countries team to the current twenty members, nine countries consortium. All the consortium members work under their own funding and it is estimated that the value of their in-kind contributions over the life of the project has been of the order of $30M. Currently, approximately 100 people worldwide are involved in the project. A very important constituency of the IRIS project is the academia: 7 universities from four countries are members of the consortium and five more US universities are associated via parallel NERI programs. To date, 97 students have worked or are working on IRIS; 59 IRIS-related graduate theses have been prepared or are in preparation, and 41 of these students have already graduated with M.S. (33) or Ph.D. (8) degrees. This ''final'' report (final only as far as the NERI program is concerned) summarizes the work performed in the first four

Efficient progressive taxes and education subsidies

NARCIS (Netherlands)

van Ewijk, C.; Tang, P.J.G.

2001-01-01

Progressive income taxes moderate wage demands by trade unions and thereby reduce unemployment, but alsothey reduce incentives to acquire skills and lower productivity of workers. The optimal response of the governmentto this dilemma is to choose a system of progressive taxes and to (partly)

Information Loss from Technological Progress

International Nuclear Information System (INIS)

Townsend, P D

2014-01-01

Progress in electronics and optics offers faster computers, and rapid communication via the internet that is matched by ever larger and evolving storage systems. Instinctively one assumes that this must be totally beneficial. However advances in software and storage media are progressing in ways which are frequently incompatible with earlier systems and the economics and commercial pressures rarely guarantee total compatibility with earlier systems. Instead, the industries actively choose to force the users to purchase new systems and software. Thus we are moving forward with new technological variants that may have access to only the most recent systems and we will have lost earlier alternatives. The reality is that increased processing speed and storage capacity are matched by an equally rapid decline in the access and survival lifetime of older information. This pattern is not limited to modern electronic systems but is evident throughout history from writing on stone and clay tablets to papyrus and paper. It is equally evident in image systems from painting, through film, to magnetic tapes and digital cameras. In sound recording we have variously progressed from wax discs to vinyl, magnetic tape and CD formats. In each case the need for better definition and greater capacity has forced the earlier systems into oblivion. Indeed proposed interactive music systems could similarly relegate music CDs to specialist collections. The article will track some of the examples and discuss the consequences as well as noting that this information loss is further compounded by developments in language and changes in cultural views of different societies

Information Loss from Technological Progress

Science.gov (United States)

Townsend, P. D.

2014-12-01

Progress in electronics and optics offers faster computers, and rapid communication via the internet that is matched by ever larger and evolving storage systems. Instinctively one assumes that this must be totally beneficial. However advances in software and storage media are progressing in ways which are frequently incompatible with earlier systems and the economics and commercial pressures rarely guarantee total compatibility with earlier systems. Instead, the industries actively choose to force the users to purchase new systems and software. Thus we are moving forward with new technological variants that may have access to only the most recent systems and we will have lost earlier alternatives. The reality is that increased processing speed and storage capacity are matched by an equally rapid decline in the access and survival lifetime of older information. This pattern is not limited to modern electronic systems but is evident throughout history from writing on stone and clay tablets to papyrus and paper. It is equally evident in image systems from painting, through film, to magnetic tapes and digital cameras. In sound recording we have variously progressed from wax discs to vinyl, magnetic tape and CD formats. In each case the need for better definition and greater capacity has forced the earlier systems into oblivion. Indeed proposed interactive music systems could similarly relegate music CDs to specialist collections. The article will track some of the examples and discuss the consequences as well as noting that this information loss is further compounded by developments in language and changes in cultural views of different societies.

Measuring progress of the global sea level observing system

Science.gov (United States)

Woodworth, Philip L.; Aarup, Thorkild; Merrifield, Mark; Mitchum, Gary T.; Le Provost, Christian

Sea level is such a fundamental parameter in the sciences of oceanography geophysics, and climate change, that in the mid-1980s, the Intergovernmental Oceanographic Commission (IOC) established the Global Sea Level Observing System (GLOSS). GLOSS was to improve the quantity and quality of data provided to the Permanent Service for Mean Sea Level (PSMSL), and thereby, data for input to studies of long-term sea level change by the Intergovernmental Panel on Climate Change (IPCC). It would also provide the key data needed for international programs, such as the World Ocean Circulation Experiment (WOCE) and later, the Climate Variability and Predictability Programme (CLIVAR).GLOSS is now one of the main observation components of the Joint Technical Commission for Oceanography and Marine Meteorology (JCOMM) of IOC and the World Meteorological Organization (WMO). Progress and deficiencies in GLOSS were presented in July to the 22nd IOC Assembly at UNESCO in Paris and are contained in the GLOSS Assessment Report (GAR) [IOC, 2003a].

ITER neutral beam system

International Nuclear Information System (INIS)

Mondino, P.L.; Di Pietro, E.; Bayetti, P.

1999-01-01

The Neutral Beam (NB) system for the International Thermonuclear Experimental Reactor (ITER) has reached a high degree of integration with the tokamak and with the rest of the plant. Operational requirements and maintainability have been considered in the design. The paper considers the integration with the tokamak, discusses design improvements which appear necessary and finally notes R and D progress in key areas. (author)

Progress of ITER vacuum vessel

Energy Technology Data Exchange (ETDEWEB)

Ioki, K., E-mail: Kimihiro.Ioki@iter.org [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-lez-Durance (France); Bayon, A. [F4E, c/ Josep Pla, No. 2, Torres Diagonal Litoral, Edificio B3, E-08019 Barcelona (Spain); Choi, C.H.; Daly, E.; Dani, S.; Davis, J.; Giraud, B.; Gribov, Y.; Hamlyn-Harris, C.; Jun, C.; Levesy, B. [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-lez-Durance (France); Kim, B.C. [NFRI, 52 Yeoeundong Yuseonggu, Daejeon 305-333 (Korea, Republic of); Kuzmin, E. [NTC “Sintez”, Efremov Inst., 189631 Metallostroy, St. Petersburg (Russian Federation); Le Barbier, R.; Martinez, J.-M. [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-lez-Durance (France); Pathak, H. [ITER-India, A-29, GIDC Electronic Estate, Sector 25, Gandhinagar 382025 (India); Preble, J. [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-lez-Durance (France); Sa, J.W. [NFRI, 52 Yeoeundong Yuseonggu, Daejeon 305-333 (Korea, Republic of); Terasawa, A.; Utin, Yu. [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-lez-Durance (France); and others

2013-10-15

Highlights: ► This covers the overall status and progress of the ITER vacuum vessel activities. ► It includes design, R and D, manufacturing and approval process of the regulators. ► The baseline design was completed and now manufacturing designs are on-going. ► R and D includes ISI, dynamic test of keys and lip-seal welding/cutting technology. ► The VV suppliers produced full-scale mock-ups and started VV manufacturing. -- Abstract: Design modifications were implemented in the vacuum vessel (VV) baseline design in 2011–2012 for finalization. The modifications are mostly due to interface components, such as support rails and feedthroughs for the in-vessel coils (IVC). Manufacturing designs are being developed at the domestic agencies (DAs) based on the baseline design. The VV support design was also finalized and tests on scale mock-ups are under preparation. Design of the in-wall shielding (IWS) has progressed, considering the assembly methods and the required tolerances. Further modifications are required to be consistent with the DAs’ manufacturing designs. Dynamic tests on the inter-modular and stub keys to support the blanket modules are being performed to measure the dynamic amplification factor (DAF). An in-service inspection (ISI) plan has been developed and R and D was launched for ISI. Conceptual design of the VV instrumentation has been developed. The VV baseline design was approved by the agreed notified body (ANB) in accordance with the French Nuclear Pressure Equipment Order procedure.

Progress of ITER vacuum vessel

International Nuclear Information System (INIS)

Ioki, K.; Bayon, A.; Choi, C.H.; Daly, E.; Dani, S.; Davis, J.; Giraud, B.; Gribov, Y.; Hamlyn-Harris, C.; Jun, C.; Levesy, B.; Kim, B.C.; Kuzmin, E.; Le Barbier, R.; Martinez, J.-M.; Pathak, H.; Preble, J.; Sa, J.W.; Terasawa, A.; Utin, Yu.

2013-01-01

Highlights: ► This covers the overall status and progress of the ITER vacuum vessel activities. ► It includes design, R and D, manufacturing and approval process of the regulators. ► The baseline design was completed and now manufacturing designs are on-going. ► R and D includes ISI, dynamic test of keys and lip-seal welding/cutting technology. ► The VV suppliers produced full-scale mock-ups and started VV manufacturing. -- Abstract: Design modifications were implemented in the vacuum vessel (VV) baseline design in 2011–2012 for finalization. The modifications are mostly due to interface components, such as support rails and feedthroughs for the in-vessel coils (IVC). Manufacturing designs are being developed at the domestic agencies (DAs) based on the baseline design. The VV support design was also finalized and tests on scale mock-ups are under preparation. Design of the in-wall shielding (IWS) has progressed, considering the assembly methods and the required tolerances. Further modifications are required to be consistent with the DAs’ manufacturing designs. Dynamic tests on the inter-modular and stub keys to support the blanket modules are being performed to measure the dynamic amplification factor (DAF). An in-service inspection (ISI) plan has been developed and R and D was launched for ISI. Conceptual design of the VV instrumentation has been developed. The VV baseline design was approved by the agreed notified body (ANB) in accordance with the French Nuclear Pressure Equipment Order procedure

A collaboration on development of requirements and guidelines for proliferation resistance of future nuclear system in the IAEA INPRO

International Nuclear Information System (INIS)

Oh, Keun Bae; Lee, Kwang Seok; Kim, Hyun Jun; Jeong, Ik; Yang, Myung Seung; Ko, Won Il

2003-10-01

This study surveyed and analyzed the existing activities and international status concerning proliferation resistance of nuclear energy systems, reviewed the features of proliferation resistance, and derived the requirements of future innovative nuclear energy systems. In IAEA INPRO, guidance for the evaluation of innovative nuclear reactors and fuel cycles on proliferation resistance was finalized through collaboration of member countries including Korea in reviewing technological status and developing the methodology for evaluation of proliferation resistance. This report, first, describes the progress of INPRO and the participation status of Korea in the project, and briefly summarizes the report of phase IA of INPRO. Next, features of proliferation resistance of nuclear systems, collaboration in the GIF and the INPRO for development of requirements and guidelines for proliferation resistance, and the final result of guidance for the evaluation of proliferation resistance were described. Finally, this study proposed measures for participation of further progress of the INPRO

Diffuse damage to central nervous system in progressive rheumatoid arthritis complicated by cerebral hermorrhage after radioisotope cisternography

International Nuclear Information System (INIS)

Tarnowska-Dziduszko, E.; Lazarowicz, J.

1980-01-01

Presented case reveals unusual reaction of central nervous system in the course of progressive rheumatoid arthritis and cerebral hemorrhage as a rare complication after radioisotope investigation of cerebro-spinal fluid spaces. Female, 58 years old which was treated for 22 years for progressive rheumatoid arthritis developed during last 3 years of life a psychoorganic syndrome with temporal epilepsy and slight left sided hemiparesis. After radioisotope cisternography appeared decerebration followed by death. On autopsy the hemorrhagic foci were found in left cerebral hemisphere and in the brain stem. Histological finding was generalized severe damage to interstitial vessels diagnosed as fibrinotic, necrotizing degeneration of capillary and arteriolar wall, significant proliferation of microglia in the white matter and brain stem. Chronic inflammatory infiltrates were present in leptomeninges. Pathogenesis of findings in connection with progressive rheumatoid arthritis and complications due to cisternography is discussed. (author)

High-energy physics at Tufts University. Progress report, August 1, 1982-July 31, 1983

International Nuclear Information System (INIS)

1983-01-01

Progress on the following topics is described: neutrino-deuterium interactions; anti pN interactions; K/sub s/ 0 /K/sub s/ 0 π - p interactions at 300 GeV/c; phi phi final states in 400 GeV/c pp; Fermilab Tevatron MPS proposals; nu D-physics proposed using HBC with internal calorimeter; Talloires neutrino workshop; photoproduction of charmed particles; streamer chamber study of anti K* 0 (890); Soudan-II nucleon decay program; CCD-detector study; optical resolution study; measuring hardware systems and data links; hadronic production of chi mesons; high-p/sub t/ inelastic hadronic reactions; and theoretical investigations

Steam generation: fossil-fired systems: utility boilers; industrial boilers; boiler auxillaries; nuclear systems: boiling water; pressurized water; in-core fuel management; steam-cycle systems: condensate/feedwater; circulating water; water treatment

International Nuclear Information System (INIS)

Anon.

1982-01-01

A survey of development in steam generation is presented. First, fossil-fired systems are described. Progress in the design of utility and industrial boilers as well as in boiler auxiliaries is traced. Improvements in coal pulverizers, burners that cut pollution and improve efficiency, fans, air heaters and economisers are noted. Nuclear systems are then described, including the BWR and PWR reactors, in-core fuel management techniques are described. Finally, steam-cycle systems for fossil-fired and nuclear power plants are reviewed. Condensate/feedwater systems, circulating water systems, cooling towers, and water treatment systems are discussed

Progress in control and data acquisition for the ITER neutral beam test facility

Energy Technology Data Exchange (ETDEWEB)

Luchetta, Adriano, E-mail: adriano.luchetta@igi.cnr.it [Consorzio RFX, Euratom-ENEA Association, Padova (Italy); Manduchi, Gabriele; Taliercio, Cesare; Soppelsa, Anton [Consorzio RFX, Euratom-ENEA Association, Padova (Italy); Paolucci, Francesco; Sartori, Filippo [Fusion for Energy, Barcelona (Spain); Barbato, Paolo; Capobianco, Roberto; Breda, Mauro; Molon, Federico; Moressa, Modesto; Polato, Sandro; Simionato, Paola; Zampiva, Enrico [Consorzio RFX, Euratom-ENEA Association, Padova (Italy)

2013-10-15

Highlights: ► An ion source experiment, referred to as SPIDER, is under construction in the ITER neutral beam test facility. ► The progress in designing and testing the SPIDER control and data acquisition system is reported. ► An original approach is proposed in using ITER CODAC and non-ITER CODAC technology. -- Abstract: SPIDER, the ion source test bed in the ITER neutral beam test facility, is under construction and its operation is expected to start in 2014. Control and data acquisition for SPIDER are undergoing final design. SPIDER CODAS, as the control and data acquisition system is referred to, is requested to manage 25 plant units, to acquire 1000 analogue signals with sampling rates ranging from a few S/s to 10 MS/s, to acquire images with up to 100 frames per second, to operate with long pulses lasting up to 1 h, and to sustain 200 MB/s data throughput into the data archive with an annual data storage amount of up to 50 TB. SPIDER CODAS software architecture integrates three open-source software frameworks each addressing specific system requirements. Slow control exploits the synergy among EPICS and Siemens S7 programmable controllers. Data handling is by MDSplus a data-centric framework that is geared towards the collection and organization of scientific data. Diagnostics based on imaging drive the design of data throughput and archive size. Fast control is implemented by using MARTe, a data-driven, object-oriented, real-time environment. The paper will describe in detail the progress of the system hardware and software architecture and will show how the software frameworks interact to provide the functions requested by SPIDER CODAS. The paper will focus on how the performance requirements can be met with the described SPIDER CODAS architecture, describing the progress achieved by carrying out prototyping activities.

Progress in control and data acquisition for the ITER neutral beam test facility

International Nuclear Information System (INIS)

Luchetta, Adriano; Manduchi, Gabriele; Taliercio, Cesare; Soppelsa, Anton; Paolucci, Francesco; Sartori, Filippo; Barbato, Paolo; Capobianco, Roberto; Breda, Mauro; Molon, Federico; Moressa, Modesto; Polato, Sandro; Simionato, Paola; Zampiva, Enrico

2013-01-01

Highlights: ► An ion source experiment, referred to as SPIDER, is under construction in the ITER neutral beam test facility. ► The progress in designing and testing the SPIDER control and data acquisition system is reported. ► An original approach is proposed in using ITER CODAC and non-ITER CODAC technology. -- Abstract: SPIDER, the ion source test bed in the ITER neutral beam test facility, is under construction and its operation is expected to start in 2014. Control and data acquisition for SPIDER are undergoing final design. SPIDER CODAS, as the control and data acquisition system is referred to, is requested to manage 25 plant units, to acquire 1000 analogue signals with sampling rates ranging from a few S/s to 10 MS/s, to acquire images with up to 100 frames per second, to operate with long pulses lasting up to 1 h, and to sustain 200 MB/s data throughput into the data archive with an annual data storage amount of up to 50 TB. SPIDER CODAS software architecture integrates three open-source software frameworks each addressing specific system requirements. Slow control exploits the synergy among EPICS and Siemens S7 programmable controllers. Data handling is by MDSplus a data-centric framework that is geared towards the collection and organization of scientific data. Diagnostics based on imaging drive the design of data throughput and archive size. Fast control is implemented by using MARTe, a data-driven, object-oriented, real-time environment. The paper will describe in detail the progress of the system hardware and software architecture and will show how the software frameworks interact to provide the functions requested by SPIDER CODAS. The paper will focus on how the performance requirements can be met with the described SPIDER CODAS architecture, describing the progress achieved by carrying out prototyping activities

Creating a dashboard to track progress toward IOM recommendations for the future of nursing.

Science.gov (United States)

Spetz, Joanne; Bates, Timothy; Chu, Lela; Lin, Jessica; Fishman, Nancy W; Melichar, Lori

2013-01-01

This article explains the process used to identify and develop a set of data used to track national progress toward the recommendations of the Institute of Medicine Committee for the Future of Nursing. The data are presented in a dashboard format to visually summarize information and quickly measure progress. The approach selected by the research team is outlined, the criteria for selecting candidate metrics are detailed, the process for seeking external guidance is described, and the final dashboard measures are presented. Finally, the methods for data collection for each metric are explicated, to guide states and local regions in the collection of their own data.

Conceptual design main progress of EAST Articulated Maintenance Arm (EAMA) system

Energy Technology Data Exchange (ETDEWEB)

Shi, Shanshuang, E-mail: shiss@ipp.ac.cn [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Laboratory of Intelligent Machines, Lappeenranta University of Technology (Finland); Song, Yuntao; Cheng, Yong [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Villedieu, Eric; Bruno, Vincent [CEA-IRFM, F-13108 Saint-Paul-Lez-Durance (France); Feng, Hansheng [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Wu, Huapeng [Laboratory of Intelligent Machines, Lappeenranta University of Technology (Finland); Wang, Peng [State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Hao, Zhiwei; Li, Yang; Wang, Kun; Pan, Hongtao [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China)

2016-03-15

Highlights: • EAST Articulated Maintenance Arm (EAMA) system is being collaboratively developed by ASIPP and CEA-IRFM. • Conceptual design for a 3-DOF wrist end effector with gripper has been finished. • Kinematic design can reach 90% of the workspace inside EAST tokamak vessel. • A prototype of EAMA arm segment has been built to validate the design. - Abstract: EAST articulated maintenance arm (EAMA) system is being collaboratively developed by ASIPP and CEA-IRFM for the purpose of remote inspection and simple maintenance operations in EAST vacuum vessel during physical experiments without breaking the ultra-high vacuum condition. The EAMA system design is based on a similar articulated inspection arm robot successfully demonstrated in Tore Supra in 2008. In order to better meet EAST configurations and maintenance requirements, optimized mechanisms and dimensions are considered for EAMA robot as upgrades. Besides, the segmented arm is equipped with a 3-DOF wrist end effector and gripper for gripping operation as well as inspection. Some calculations and simulations on statics, kinematics and workspace of EAMA have been presented to validate the feasibility. This paper introduces the overall design of the EAMA robot and presents implementation progress.

Conceptual design main progress of EAST Articulated Maintenance Arm (EAMA) system

International Nuclear Information System (INIS)

Shi, Shanshuang; Song, Yuntao; Cheng, Yong; Villedieu, Eric; Bruno, Vincent; Feng, Hansheng; Wu, Huapeng; Wang, Peng; Hao, Zhiwei; Li, Yang; Wang, Kun; Pan, Hongtao

2016-01-01

Highlights: • EAST Articulated Maintenance Arm (EAMA) system is being collaboratively developed by ASIPP and CEA-IRFM. • Conceptual design for a 3-DOF wrist end effector with gripper has been finished. • Kinematic design can reach 90% of the workspace inside EAST tokamak vessel. • A prototype of EAMA arm segment has been built to validate the design. - Abstract: EAST articulated maintenance arm (EAMA) system is being collaboratively developed by ASIPP and CEA-IRFM for the purpose of remote inspection and simple maintenance operations in EAST vacuum vessel during physical experiments without breaking the ultra-high vacuum condition. The EAMA system design is based on a similar articulated inspection arm robot successfully demonstrated in Tore Supra in 2008. In order to better meet EAST configurations and maintenance requirements, optimized mechanisms and dimensions are considered for EAMA robot as upgrades. Besides, the segmented arm is equipped with a 3-DOF wrist end effector and gripper for gripping operation as well as inspection. Some calculations and simulations on statics, kinematics and workspace of EAMA have been presented to validate the feasibility. This paper introduces the overall design of the EAMA robot and presents implementation progress.

Characterize and Model Final Waste Formulations and Offgas Solids from Thermal Treatment Processes - FY-98 Final Report for LDRD 2349

Energy Technology Data Exchange (ETDEWEB)

Kessinger, Glen Frank; Nelson, Lee Orville; Grandy, Jon Drue; Zuck, Larry Douglas; Kong, Peter Chuen Sun; Anderson, Gail

1999-08-01

The purpose of LDRD #2349, Characterize and Model Final Waste Formulations and Offgas Solids from Thermal Treatment Processes, was to develop a set of tools that would allow the user to, based on the chemical composition of a waste stream to be immobilized, predict the durability (leach behavior) of the final waste form and the phase assemblages present in the final waste form. The objectives of the project were: • investigation, testing and selection of thermochemical code • development of auxiliary thermochemical database • synthesis of materials for leach testing • collection of leach data • using leach data for leach model development • thermochemical modeling The progress toward completion of these objectives and a discussion of work that needs to be completed to arrive at a logical finishing point for this project will be presented.

Quantitative MRI study of progressive cerebral atrophy in multiple system atrophy

International Nuclear Information System (INIS)

Konagaya, Masaaki; Matsuoka, Yukihiko; Konagaya, Yoko

2002-01-01

We investigated cerebral atrophy in multiple system atrophy (MSA) by quantitative analysis of MRI. The subjects were 28 patients with MSA (14 striato-nigral degeneration; SND, 14 olivo-ponto-cerebellar atrophy; OPCA. 106 MRI examinations were performed totally) and 85 normal persons for control. The ratios of the ventral pons to the infratentorial space in the sagittal section, the putamen, cerebrum, frontal lobe and parietal and occipital lobes to the intracranial space in the horizontal section, and the temporal lobe to the intracranial space in the coronal section were measured. In the early stage of the disease, OPCA showed significant atrophy of the ventral pons compared with SND, and conversely, SND demonstrated significantly smaller putamen than that in OPCA. According to the progression of the disease, the atrophy of these neural tissues progressed, which resulted in so significant differences between SND and OPCA. The cerebral atrophy was observed in 17 MSA patients. The atrophy of the frontal lobe was much frequent and prominent to that in the temporal lobe and parietal and occipital lobes. SND showed higher incidence of the cerebral atrophy than OPCA in the early stage of the disease. In long period follow-up cases, one case showed cerebral atrophy in earlier stage, and another case in late stage. We indicated the involvement of the cerebral hemispheres in MSA, especially the frontal lobe. (author)

Quantitative MRI study of progressive cerebral atrophy in multiple system atrophy

Energy Technology Data Exchange (ETDEWEB)

Konagaya, Masaaki; Matsuoka, Yukihiko [Suzuka National Hospital, Suzuka, Mie (Japan); Konagaya, Yoko [JR Tokai General Hospital, Nagoya (Japan)

2002-02-01

We investigated cerebral atrophy in multiple system atrophy (MSA) by quantitative analysis of MRI. The subjects were 28 patients with MSA (14 striato-nigral degeneration; SND, 14 olivo-ponto-cerebellar atrophy; OPCA. 106 MRI examinations were performed totally) and 85 normal persons for control. The ratios of the ventral pons to the infratentorial space in the sagittal section, the putamen, cerebrum, frontal lobe and parietal and occipital lobes to the intracranial space in the horizontal section, and the temporal lobe to the intracranial space in the coronal section were measured. In the early stage of the disease, OPCA showed significant atrophy of the ventral pons compared with SND, and conversely, SND demonstrated significantly smaller putamen than that in OPCA. According to the progression of the disease, the atrophy of these neural tissues progressed, which resulted in so significant differences between SND and OPCA. The cerebral atrophy was observed in 17 MSA patients. The atrophy of the frontal lobe was much frequent and prominent to that in the temporal lobe and parietal and occipital lobes. SND showed higher incidence of the cerebral atrophy than OPCA in the early stage of the disease. In long period follow-up cases, one case showed cerebral atrophy in earlier stage, and another case in late stage. We indicated the involvement of the cerebral hemispheres in MSA, especially the frontal lobe. (author)

The development of KMRR schedule and progress control system (KSPCS) for the master schedule of KMRR project

International Nuclear Information System (INIS)

Choi, Chang Woong; Lee, Tae Joon; Kim, Joon Yun; Cho, Yun Ho; Hah, Jong Hyun

1993-07-01

This report was to development the computerized schedule and progress control system for the master schedule of KMRR project with ARTEMIS 7000/386 CM (Ver. 7.4.2.) based on project management theory (PERT/CPM, PDM, and S-curve). This system has been efficiently used for KMRR master schedule and will be utilized for the detail scheduling of KMRR project. (Author) 23 refs., 26 figs., 52 tabs

The development of KMRR schedule and progress control system (KSPCS) for the master schedule of KMRR project

Energy Technology Data Exchange (ETDEWEB)

Choi, Chang Woong; Lee, Tae Joon; Kim, Joon Yun; Cho, Yun Ho; Hah, Jong Hyun [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

1993-07-01

This report was to development the computerized schedule and progress control system for the master schedule of KMRR project with ARTEMIS 7000/386 CM (Ver. 7.4.2.) based on project management theory (PERT/CPM, PDM, and S-curve). This system has been efficiently used for KMRR master schedule and will be utilized for the detail scheduling of KMRR project. (Author) 23 refs., 26 figs., 52 tabs.

Inertial confinement fusion driver enhancements: Final focusing systems and compact heavy-ion driver designs

International Nuclear Information System (INIS)

Bieri, R.L.

1991-01-01

Required elements of an inertial confinement fusion power plant are modeled and discussed. A detailed analysis of two critical elements of candidate drivers is done, and new component designs are proposed to increase the credibility and feasibility of each driver system. An analysis of neutron damage to the final elements of a laser focusing system is presented, and multilayer -- dielectric mirrors are shown to have damage lifetimes which axe too short to be useful in a commercial power plant. A new final-focusing system using grazing incidence metal mirrors to protect sensitive laser optics is designed and shown to be effective in extending the lifetime of the final focusing system. The reflectivities and damage limits of grazing incidence metal mirrors are examined in detail, and the required mirror sizes are shown to be compatible with the beam sizes and illumination geometries currently envisioned for laser drivers. A detailed design and analysis is also done for compact arrays of superconducting magnetic quadrupoles, which are needed in a multi-beam heavy-ion driver. The new array model is developed in more detail than some previous conceptual designs and models arrays which are more compact than arrays scaled from existing single -- quadrupole designs. The improved integrated model for compact arrays is used to compare the effects of various quadrupole array design choices on the size and cost of a heavy-ion driver. Array design choices which significantly affect the cost of a heavy-ion driver include the choice of superconducting material and the thickness of the collar used to support the winding stresses. The effect of these array design choices on driver size and cost is examined and the array model is used to estimate driver cost savings and performance improvements attainable with aggressive quadrupole array designs with high-performance superconductors

Progress of Space Charge Research on Oil-Paper Insulation Using Pulsed Electroacoustic Techniques

Directory of Open Access Journals (Sweden)

Chao Tang

2016-01-01

Full Text Available This paper focuses on the space charge behavior in oil-paper insulation systems used in power transformers. It begins with the importance of understanding the space charge behavior in oil-paper insulation systems, followed by the introduction of the pulsed electrostatic technique (PEA. After that, the research progress on the space charge behavior of oil-paper insulation during the recent twenty years is critically reviewed. Some important aspects such as the environmental conditions and the acoustic wave recovery need to be addressed to acquire more accurate space charge measurement results. Some breakthroughs on the space charge behavior of oil-paper insulation materials by the research team at the University of Southampton are presented. Finally, future work on space charge measurement of oil-paper insulation materials is proposed.

Progress of data processing system in JT-60 utilizing the UNIX-based workstations

International Nuclear Information System (INIS)

Sakata, Shinya; Kiyono, Kimihiro; Oshima, Takayuki; Sato, Minoru; Ozeki, Takahisa

2007-07-01

JT-60 data processing system (DPS) possesses three-level hierarchy. At the top level of hierarchy is JT-60 inter-shot processor (MSP-ISP), which is a mainframe computer, provides communication with the JT-60 supervisory control system and supervises the internal communication inside the DPS. The middle level of hierarchy has minicomputers and the bottom level of hierarchy has individual diagnostic subsystems, which consist of the CAMAC and VME modules. To meet the demand for advanced diagnostics, the DPS has been progressed in stages from a three-level hierarchy system, which was dependent on the processing power of the MSP-ISP, to a two-level hierarchy system, which is decentralized data processing system (New-DPS) by utilizing the UNIX-based workstations and network technology. This replacement had been accomplished, and the New-DPS has been started to operate in October 2005. In this report, we describe the development and improvement of the New-DPS, whose functions were decentralized from the MSP-ISP to the UNIX-based workstations. (author)

Progress of R and D on seismic emergency information system

International Nuclear Information System (INIS)

2000-09-01

After the Great Hansin-Awaji Earthquake Disaster occurred in 1995, the Science and Technology Agency commenced 'Frontier Research Program on Earthquake' in FY1996. As a part of this research program, four-year program on 'Research on Real-time Earthquake Information Transmission' has been carried out at JAERI since FY1997. Through the experience of the above earthquake disaster, the importance of accurate and prompt seismic information transmission immediately after the occurrence of the earthquake has been recognized from the viewpoint of disaster mitigation. Under this circumstance, the main activity in Real-time Earthquake Information Transmission Research at JAERI has been placed on the development of a seismic emergency information system. In order to respond to the above R and D, Seismic Emergency Information System Research Team was organized in JAERI in FY1998. In the meantime a part of this R and D program is performed under the coordinated research between JAERI and NIED(National Research Institute for Science and Disaster Prevention). This report describes the recent progress of R and D until FY1999. In the R and D, estimation techniques of hypocenter, fault and earthquake motion parameters, in which the latest results in the field of earthquake engineering were involved, were developed. Until the end of FY1999, the main part of the system, in which the above estimation techniques are introduced, is completed. By this system the seismic information is being transmitted using E-mail and homepage through the inter-net. In addition the databases on the estimated earthquake motion parameter distribution under scenario earthquakes and the surface soil amplification function around JAERI-Tokai site are prepared to examine the applicability of the system. (author)

Gradual progression of intrapulmonary lymph nodes associated with usual interstitial pneumonia in progressive systemic sclerosis on chest radiographs and CT

Energy Technology Data Exchange (ETDEWEB)

Ohm, Joon Young; Chung, Myung Hee; Kim, Seon Mun [The Catholic Univ. of Korea, Seoul (Korea, Republic of); Kim, Yong Hyun [The Catholic Univ. of Korea, Bucheon (Korea, Republic of)

2012-10-15

A 40 year old female visited the clinic for evaluation of Raynaud's phenomenon for a period of four years. The initial chest radiograph showed a fine reticular density and ground glass opacity with lower lobe predominance. These findings are consistent interstitial fibrosis. Additionally, high resolution CT showed multiple, small, coexisting nodular opacities, ranging from 3 to 7 mm in size in both lungs. These nodules grew up to 1.5 cm and showed moderate enhancement. Because of the rareness of intrapulmonary lymph node in patient of progressive systemic sclerosis, we couldn't exclude the possibility of malignancy. These nodules are turned out to be intrapulmonary lymph nodes on video assisted thoracoscopic lung biopsy.

Determination of lactic acid level in systemic liquids in children with progressive encephalopathies.

Science.gov (United States)

Marszał, Elzbieta; Wojaczyńska-Stanek, Katarzyna; Pietruszewski, Jerzy; Emich-Widera, Ewa; Bielińska-Bujniewicz, Eugenia

2002-03-01

This article reports the results of research into the activities of lactic acid concentrations in the body fluids of children with progressive encephalopathies (PE) in comparison to patients with non-progressive encephalopathies (NPE) and those with non-progressive encephalopathies with concomitant epilepsy (NPEE). The study was designed to determine whether there is difference between the serum and CSF lactic acid concentrations in children with progressive encephalopathies (PE), static (non-progressive) encephalopathies (NPE) and non progressive encephalopathies with concomitant epilepsy (NPEE), and whether the clinical status correlates with the concentration of these biochemical markers in children with PE. The assessment involved 138 children of both sexes, whose age ranged between 8 months and 15 years, diagnosed and treated in the Neurology Department at the Pediatric Clinic of the Silesian Medical Academy in Katowice between 1995 and 1997. Lactate concentrations were determined in serum and cerebro-spinal fluid and analyzed statistically. The findings showed higher serum and CSF concentrations in children with PE than in patients who manifested non-progressive forms of encephalopathy. The degree of clinical symptom aggravation in PE children was likewise analyzed and compared to the values of lactate concentrations in body fluids; however, no correlation was found between these parameters. Children with progressive encephalopathies present higher lactate concentrations in serum and cerebrospinal fluid than patients with static (non-progressive) encephalopathy.

The development and progress of XeCl Excimer laser system

Science.gov (United States)

Zhang, Yongsheng; Ma, Lianying; Wang, Dahui; Zhao, Xueqing; Zhu, Yongxiang; Hu, Yun; Qian, Hang; Shao, Bibo; Yi, Aiping; Liu, Jingru

2015-05-01

A large angularly multiplexed XeCl Excimer laser system is under development at the Northwest Institute of Nuclear Technology (NINT). It is designed to explore the technical issues of uniform and controllable target illumination. Short wavelength, uniform and controllable target illumination is the fundamental requirement of high energy density physics research using large laser facility. With broadband, extended light source and multi-beam overlapping techniques, rare gas halide Excimer laser facility will provide uniform target illumination theoretically. Angular multiplexing and image relay techniques are briefly reviewed and some of the limitations are examined to put it more practical. The system consists of a commercial oscillator front end, three gas discharge amplifiers, two electron beam pumped amplifiers and the optics required to relay, encode and decode the laser beam. An 18 lens array targeting optics direct and focus the laser in the vacuum target chamber. The system is operational and currently undergoing tests. The total 18 beams output energy is more than 100J and the pulse width is 7ns (FWHM), the intensities on the target will exceed 1013W/cm2. The aberration of off-axis imaging optics at main amplifier should be minimized to improve the final image quality at the target. Automatic computer controlled alignment of the whole system is vital to efficiency and stability of the laser system, an array of automatic alignment model is under test and will be incorporated in the system soon.

Progress in design and integration of the ITER Electron Cyclotron H and CD system

International Nuclear Information System (INIS)

Darbos, C.; Henderson, M.; Albajar, F.; Bigelow, T.; Bonicelli, T.; Chavan, R.; Denisov, G.G.; Fasel, D.; Heidinger, R.; Hogge, J.P.; Kobayashi, N.; Piosczyk, B.; Rao, S.L.; Rasmussen, D.; Saibene, G.; Sakamoto, K.; Takahashi, K.; Thumm, M.

2009-01-01

The Electron Cyclotron system for ITER is an in-kind procurement shared between five parties and the total installed power will be 24 MW, corresponding to a nominal injected power of 20 MW to the plasma, with a possible upgrade up to 48 MW (corresponding to 40 MW injected). Some critical issues have been raised and changes are proposed to simplify these procurements and to facilitate the integration into ITER. The progress in the design and the integration of the EC system into the whole project is presented in this paper, as well as some issues still under studies and some recommendations made by external expert committees.

Systems study 'Alternative Entsorgung'. Final report. Technical annex 6

International Nuclear Information System (INIS)

1984-08-01

In the conditioning plant, fuel elements which have been stored for ten years are loaded into transport containers, unloaded, identified and welded into a dry storage box. The dry store barrel is introduced into a final storage container, which, after being closed, is packed in lost shielding. This so-called final storage barrel is finally placed in a transport container and leaves the conditioning plant in this form by rail for transport to the final storage mine. The fuel element method of treatment 'packing of three complete fuel elements' was used as the reference process. In addition, the method of treatment 'fuel elements dismantled into fuel rods' was also examined. The handling of fuel elements and secondary waste treatment in the reference process are described in detail. (orig./HP) [de

Design progress of the ITER vacuum vessel sectors and port structures

International Nuclear Information System (INIS)

Utin, Yu.; Ioki, K.; Alekseev, A.; Bachmann, Ch.; Cho, S.; Chuyanov, V.; Jones, L.; Kuzmin, E.; Morimoto, M.; Nakahira, M.; Sannazzaro, G.

2007-01-01

Recent progress of the ITER vacuum vessel (VV) design is presented. As the ITER construction phase approaches, the VV design has been improved and developed in more detail with the focus on better performance, improved manufacture and reduced cost. Based on achievements of manufacturing studies, design improvement of the typical VV Sector (no. 1) has been nearly finalized. Design improvement of other sectors is in progress-in particular, of the VV Sectors no. 2 and no. 3 which interface with tangential ports for the neutral beam (NB) injection. For all sectors, the concept for the in-wall shielding has progressed and developed in more detail. The design progress of the VV sectors has been accompanied by the progress of the port structures. In particular, design of the NB ports was advanced with the focus on the beam-facing components to handle the heat input of the neutral beams. Structural analyses have been performed to validate all design improvements

76 FR 16534 - Hazardous Waste Management System Identification and Listing of Hazardous Waste; Final Exclusion

Science.gov (United States)

2011-03-24

... Waste Management System Identification and Listing of Hazardous Waste; Final Exclusion AGENCY...) on a one-time basis from the lists of hazardous waste, a certain solid waste generated at its Mt... waste is [[Page 16535

Demonstration of a Small Modular BioPower System Using Poultry Litter; FINAL

International Nuclear Information System (INIS)

John P. Reardon; Art Lilley; Jim Wimberly; Kingsbury Browne; Kelly Beard; Jack Avens

2002-01-01

The purpose of this project was to assess poultry grower residue, or litter (manure plus absorbent biomass), as a fuel source for Community Power Corporation's small modular biopower system (SMB). A second objective was to assess the poultry industry to identify potential ''on-site'' applications of the SMB system using poultry litter residue as a fuel source, and to adapt CPC's existing SMB to generate electricty and heat from the poultry litter biomass fuel. Bench-scale testing and pilot testing were used to gain design information for the SMB retrofit. System design approach for the Phase II application of the SMB was the goal of Phase I testing. Cost estimates for an onsite poultry litter SMB were prepared. Finally, a market estimate was prepared for implementation of the on-farm SMB using poultry litter

Systemic Inflammation in Progressive Multiple Sclerosis Involves Follicular T-Helper, Th17- and Activated B-Cells and Correlates with Progression

DEFF Research Database (Denmark)

Romme Christensen, Jeppe; Börnsen, Lars; Ratzer, Rikke

2013-01-01

with disease progression, using flow cytometry and gene expression analysis of CD4(+) and CD8(+)T-cells, B-cells, monocytes and dendritic cells. Furthermore, gene expression of cerebrospinal fluid cells was studied. Flow cytometry studies revealed increased frequencies of ICOS(+)TFH-cells in peripheral blood...... increased in PPMS and SPMS. In the analysis of B-cells, we found a significant increase of plasmablasts and DC-SIGN(+) and CD83(+)B-cells in SPMS. ICOS(+)TFH-cells and DC-SIGN(+)B-cells correlated with disease progression in SPMS patients. Gene expression analysis of peripheral blood cell subsets...... substantiated the flow cytometry findings by demonstrating increased expression of IL21, IL21R and ICOS in CD4(+)T-cells in progressive MS. Cerebrospinal fluid cells from RRMS and progressive MS (pooled SPMS and PPMS patients) had increased expression of TFH-cell and plasmablast markers. In conclusion...

Impedimetric biosensors for medical applications current progress and challenges

CERN Document Server

Rushworth, Jo V; Goode, Jack A; Pike, Douglas J; Ahmed, Asif; Millner, Paul

2014-01-01

In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric biosensors and the principles of electrochemical impedance spectroscopy. Next, the current state-of-the art in terms of the science and technology underpinning impedance-based biosensors is reviewed in detail. The layer-by-layer construction of impedimetric sensors is described, including the design of electrodes, their nano-modification, transducer surface functionalization and the attachment of different bioreceptors. The current challenges of translating lab-based biosensor platforms into commercially-available devices that function with real patient samples at the POC are presented; this includes a consideration of systems integration, microfluidics and biosensor regeneration. The final section of this monograph ...

Progress and Prospects of CRISPR/Cas Systems in Insects and Other Arthropods

Directory of Open Access Journals (Sweden)

Dan Sun

2017-09-01

Full Text Available Clustered regularly interspaced short palindromic repeats (CRISPR and the CRISPR-associated gene Cas9 represent an invaluable system for the precise editing of genes in diverse species. The CRISPR/Cas9 system is an adaptive mechanism that enables bacteria and archaeal species to resist invading viruses and phages or plasmids. Compared with zinc finger nucleases and transcription activator-like effector nucleases, the CRISPR/Cas9 system has the advantage of requiring less time and effort. This efficient technology has been used in many species, including diverse arthropods that are relevant to agriculture, forestry, fisheries, and public health; however, there is no review that systematically summarizes its successful application in the editing of both insect and non-insect arthropod genomes. Thus, this paper seeks to provide a comprehensive and impartial overview of the progress of the CRISPR/Cas9 system in different arthropods, reviewing not only fundamental studies related to gene function exploration and experimental optimization but also applied studies in areas such as insect modification and pest control. In addition, we also describe the latest research advances regarding two novel CRISPR/Cas systems (CRISPR/Cpf1 and CRISPR/C2c2 and discuss their future prospects for becoming crucial technologies in arthropods.

Beyond Therapy Dogs: Coordinating Large-Scale Finals Week Activities

Science.gov (United States)

Flynn, Holly

2017-01-01

Finals week activities have become increasingly popular in academic libraries in the last few years, but what is a library to do when it is not allowed to have therapy dogs? This column examines a progression of increasingly popular activities at Michigan State University Libraries. Included is an assessment of what makes them popular, our…

Biomedical Computing Technology Information Center (BCTIC): Final progress report, March 1, 1986-September 30, 1986

International Nuclear Information System (INIS)

1987-01-01

During this time, BCTIC packaged and disseminated computing technology and honored all requests made before September 1, 1986. The final month of operation was devoted to completing code requests, returning submitted codes, and sending out notices of BCTIC's termination of services on September 30th. Final BCTIC library listings were distributed to members of the active mailing list. Also included in the library listing are names and addresses of program authors and contributors in order that users may have continued support of their programs. The BCTIC library list is attached

The hypocretin/orexin system in sleep disorders: preclinical insights and clinical progress.

Science.gov (United States)

Chow, Matthew; Cao, Michelle

2016-01-01

Much of the understanding of the hypocretin/orexin (HCRT/OX) system in sleep-wake regulation came from narcolepsy-cataplexy research. The neuropeptides hypocretin-1 and -2/orexin-A and -B (HCRT-1 and -2/OX-A and -B, respectively), as we know, are intimately involved in the regulation wakefulness. The HCRT/OX system regulates sleep-wake control through complex interactions between monoaminergic/cholinergic (wake-promoting) and gamma-aminobutyric acid-ergic (sleep-promoting) neuronal systems. Deficiency of HCRT/OX results in loss of sleep-wake control or stability with consequent unstable transitions between wakefulness to nonrapid eye movement and rapid eye movement sleep. This manifests clinically as abnormal daytime sleepiness with sleep attacks and cataplexy. Research on the development of HCRT/OX agonists and antagonists for the treatment of sleep disorders has dramatically increased with the US Food and Drug Administration approval of the first-in-class dual HCRT/OX receptor antagonist for the treatment of insomnia. This review focuses on the origin, mechanisms of HCRT/OX receptors, clinical progress, and applications for the treatment of sleep disorders.

Vibrating-Wire, Supercooled Liquid Water Content Sensor Calibration and Characterization Progress

Science.gov (United States)

King, Michael C.; Bognar, John A.; Guest, Daniel; Bunt, Fred

2016-01-01

NASA conducted a winter 2015 field campaign using weather balloons at the NASA Glenn Research Center to generate a validation database for the NASA Icing Remote Sensing System. The weather balloons carried a specialized, disposable, vibrating-wire sensor to determine supercooled liquid water content aloft. Significant progress has been made to calibrate and characterize these sensors. Calibration testing of the vibrating-wire sensors was carried out in a specially developed, low-speed, icing wind tunnel, and the results were analyzed. The sensor ice accretion behavior was also documented and analyzed. Finally, post-campaign evaluation of the balloon soundings revealed a gradual drift in the sensor data with increasing altitude. This behavior was analyzed and a method to correct for the drift in the data was developed.

Design optimization of the International Linear Collider Final Focus System with a long L*

CERN Document Server

Plassard, Fabien

This Master's Thesis work has been done in the Aerospace Engineering master's programme framework and carried out at the European Organization for Nuclear Research (CERN). It was conducted under the 500 GeV e-e+ International Linear Collider (ILC) study and focused on the design and performance optimization of the Final Focus System (FFS). The purpose of the final focus system of the future linear colliders (ILC and CLIC) is to demagnify the beam to the required transverse size at the interaction point (IP). The FFS is designed for a flat-beam in a compact way based on a local chromaticity correction which corrects both horizontal and vertical chromaticities simultaneously. An alternative FFS configuration based on the traditional scheme with two dedicated chromatic correction sections for horizontal and vertical chromaticities and a long L * option has been developed. A longer free space between the last quadrupole and the IP allows to place the last quadrupole on a stable ground, with fewer engineering ...

Laser Shot Peening System Final Report CRADA No. TC-1369-96

Energy Technology Data Exchange (ETDEWEB)

Stuart, B. C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Harris, F. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2017-09-27

This CRADA project was established with a primary goal to develop a laser shot peening system which could operate at production throughput rates and produce the desired depth and intensity of induced shots. The first objective was to understand all parameters required for acceptable peening, including pulse energy, pulse temporal format, pulse spatial format, sample configuration and tamping mechanism. The next objective was to demonstrate the technique on representative samples and then on representative parts. The final objective was to implement the technology into a meaningful industrial peen.

Medicare Program: Hospital Outpatient Prospective Payment and Ambulatory Surgical Center Payment Systems and Quality Reporting Programs; Short Inpatient Hospital Stays; Transition for Certain Medicare-Dependent, Small Rural Hospitals Under the Hospital Inpatient Prospective Payment System; Provider Administrative Appeals and Judicial Review. Final rule with comment period; final rule.

Science.gov (United States)

2015-11-13

This final rule with comment period revises the Medicare hospital outpatient prospective payment system (OPPS) and the Medicare ambulatory surgical center (ASC) payment system for CY 2016 to implement applicable statutory requirements and changes arising from our continuing experience with these systems. In this final rule with comment period, we describe the changes to the amounts and factors used to determine the payment rates for Medicare services paid under the OPPS and those paid under the ASC payment system. In addition, this final rule with comment period updates and refines the requirements for the Hospital Outpatient Quality Reporting (OQR) Program and the ASC Quality Reporting (ASCQR) Program. Further, this document includes certain finalized policies relating to the hospital inpatient prospective payment system: Changes to the 2-midnight rule under the short inpatient hospital stay policy; and a payment transition for hospitals that lost their status as a Medicare-dependent, small rural hospital (MDH) because they are no longer in a rural area due to the implementation of the new Office of Management and Budget delineations in FY 2015 and have not reclassified from urban to rural before January 1, 2016. In addition, this document contains a final rule that finalizes certain 2015 proposals, and addresses public comments received, relating to the changes in the Medicare regulations governing provider administrative appeals and judicial review relating to appropriate claims in provider cost reports.

The Center for Space Telemetering and Telecommunications Systems

Science.gov (United States)

Horan, S.; DeLeon, P.; Borah, D.; Lyman, R.

2003-01-01

This report comprises the final technical report for the research grant 'Center for Space Telemetering and Telecommunications Systems' sponsored by the National Aeronautics and Space Administration's Goddard Space Flight Center. The grant activities are broken down into the following technology areas: (1) Space Protocol Testing; (2) Autonomous Reconfiguration of Ground Station Receivers; (3) Satellite Cluster Communications; and (4) Bandwidth Efficient Modulation. The grant activity produced a number of technical reports and papers that were communicated to NASA as they were generated. This final report contains the final summary papers or final technical report conclusions for each of the project areas. Additionally, the grant supported students who made progress towards their degrees while working on the research.

Maintaining the uranium resources data system and assessing the 1991 US uranium potential resources. Final report

Energy Technology Data Exchange (ETDEWEB)

McCammon, R.B. [Geological Survey, Reston, VA (United States); Finch, W.I.; Grundy, W.D.; Pierson, C.T. [Geological Survey, Denver, CO (United States)

1992-12-31

The Energy Information Administration`s (EIA) Uranium Resource Assessment Data (URAD) System contains information on potential resources (undiscovered) of uranium in the United States. The purpose of this report is: (1) to describe the work carried out to maintain and update the URAD system; (2)to assess the 1991 U.S. uranium potential resources in various cost categories; and (3) to describe the progress that has been made to automate the generation of the assessment reports and their subsequent transmittal by diskette.

Radiation damage and waste management options for the sombrero final focus system and neutron dumps

International Nuclear Information System (INIS)

Reyes, S.; Latkowski, J.F.; Meier, W.R.; Reyes, S.

2000-01-01

Previous studies of the safety and environmental aspects of the SOMBRERO inertial fusion energy (IFE) power plant design did not completely address the issues associated with the final focus system. While past work calculated neutron fluences for a grazing incidence metal mirror (GIMM) and a final focus mirror, scattering off of the final optical component was not included, and thus, fluences in the final focus mirror were significantly underestimated. In addition, past work did not consider neutron-induced gamma-rays. Finally, power plant lifetime waste volumes may have been underestimated as neutron activation of the neutron dumps and building structure were not addressed. In the present work, a modified version of the SOMBRERO target building is presented where a significantly larger open solid-angle fraction (5%) is used to enhance beam smoothing of a diode-pumped solid-state laser (DPSSL). The GIMMs are replaced with transmissive fused silica wedges and have been included in three-dimensional neutron and photon transport calculations. This work shows that a power plant with a large open solid-angle fraction, needed for beam smoothing with a DPSSL, is acceptable from tritium breeding, and neutron activation points-of-view. (authors)

Progress risk assessment of oral premalignant lesions with saliva miRNA analysis

International Nuclear Information System (INIS)

Yang, Ya; Li, Yue-xiu; Yang, Xi; Jiang, Long; Zhou, Zuo-jun; Zhu, Ya-qin

2013-01-01

Oral cancer develops through multi-stages: from normal to mild (low grade) dysplasia (LGD), moderate dysplasia, and severe (high grade) dysplasia (HGD), to carcinoma in situ (CIS) and finally invasive oral squamous cell carcinomas (OSCC). Clinical and histological assessments are not reliable in predicting which precursor lesions will progress. The aim of this study was to assess the potential of a noninvasive approach to assess progress risk of oral precancerous lesions. We first used microRNA microarray to profile progressing LGD oral premaligant lesions (OPLs) from non-progressing LGD OPLs in order to explore the possible microRNAs deregulated in low grade OPLs which later progressed to HGD or OSCC. We then used RT-qPCR to detect miRNA targets from the microarray results in saliva samples of these patients. We identified a specific miRNA signature that is aberrantly expressed in progressing oral LGD leukoplakias. Similar expression patterns were detected in saliva samples from these patients. These results show promise for using saliva miRNA signature for monitoring of cancer precursor lesions and early detection of disease progression

Progress in linear optics, non-linear optics and surface alignment of liquid crystals

Science.gov (United States)

Ong, H. L.; Meyer, R. B.; Hurd, A. J.; Karn, A. J.; Arakelian, S. M.; Shen, Y. R.; Sanda, P. N.; Dove, D. B.; Jansen, S. A.; Hoffmann, R.

We first discuss the progress in linear optics, in particular, the formulation and application of geometrical-optics approximation and its generalization. We then discuss the progress in non-linear optics, in particular, the enhancement of a first-order Freedericksz transition and intrinsic optical bistability in homeotropic and parallel oriented nematic liquid crystal cells. Finally, we discuss the liquid crystal alignment and surface effects on field-induced Freedericksz transition.

Columbia River System Operation Review final environmental impact statement. Appendix I: Power

International Nuclear Information System (INIS)

1995-11-01

The System Operation Review (SOR) is a study and environmental compliance process being used by the three Federal agencies to analyze future operations of the system and river use issues. The goal of the SOR is to achieve a coordinated system operation strategy for the river that better meets the needs of all river users. This technical appendix addresses only the effects of alternative system operating strategies for managing the Columbia River system. This appendix discusses the work performed by the SOR Power Work Group. The Power Work Group (PWG) had several major responsibilities: first, to determine the effects of each of the various system operating strategies (SOS) on the Northwest regional power system; second, given these effects, to determine what, if any, actions are required to meet forecasted regional energy consumption; and finally, to estimate the cost for serving the forecasted regional energy consumption. The Northwest regional power system consists of Federal and non-Federal hydroelectric power projects (hydropower or hydro projects) on the main stem of the Columbia and Snake Rivers, numerous smaller hydro projects on other river reaches, and a number of thermal plants (coal, nuclear and combustion turbines)

Systemic Chemotherapy for Progression of Brain Metastases in Extensive-Stage Small Cell Lung Cancer

Directory of Open Access Journals (Sweden)

Nagla Abdel Karim

2015-01-01

Full Text Available Lung cancer is the most common cause of cancer related mortality in men and women. Approximately 15% of lung cancers are small cell type. Chemotherapy and radiation are the mainstay treatments. Currently, the standard chemotherapy regimen includes platinum/etoposide. For extensive small cell lung cancer, irinotecan and cisplatin have also been used. Patients with relapsed small cell lung cancer have a very poor prognosis, and the morbidity increases with brain metastases. Approximately 10%–14% of small cell lung cancer patients exhibit brain metastases at the time of diagnosis, which increases to 50%–80% as the disease progresses. Mean survival with brain metastases is reported to be less than six months, thus calling for improved regimens. Here we present a case series of patients treated with irinotecan for progressive brain metastases in small cell lung cancer, which serves as a reminder of the role of systemic chemotherapy in this setting.

Advanced Fuel Cycle Initiative University Fellowship Program. Final Progress Report

International Nuclear Information System (INIS)

Dixon, Cathy

2012-01-01

2004-2011 Final Report for AFCI University Fellowship Program. The goal of this effort was to be supportive of university students and university programs - particularly those students and programs that will help to strengthen the development of nuclear-related fields. The program also supported the stability of the nuclear infrastructure and developed research partnerships that are helping to enlarge the national nuclear science technology base. In this fellowship program, the U.S. Department of Energy sought master's degree students in nuclear, mechanical, or chemical engineering, engineering/applied physics, physics, chemistry, radiochemistry, or fields of science and engineering applicable to the AFCI/Gen IV/GNEP missions in order to meet future U.S. nuclear program needs. The fellowship program identified candidates and selected full time students of high-caliber who were taking nuclear courses as part of their degree programs. The DOE Academic Program Managers encouraged fellows to pursue summer internships at national laboratories and supported the students with appropriate information so that both the fellows and the nation's nuclear energy objectives were successful.

Basic concept of common reactor physics code systems. Final report of working party on common reactor physics code systems (CCS)

International Nuclear Information System (INIS)

2004-03-01

A working party was organized for two years (2001-2002) on common reactor physics code systems under the Research Committee on Reactor Physics of JAERI. This final report is compilation of activity of the working party on common reactor physics code systems during two years. Objectives of the working party is to clarify basic concept of common reactor physics code systems to improve convenience of reactor physics code systems for reactor physics researchers in Japan on their various field of research and development activities. We have held four meetings during 2 years, investigated status of reactor physics code systems and innovative software technologies, and discussed basic concept of common reactor physics code systems. (author)

Progress report 1986-1987 Department of Physics

International Nuclear Information System (INIS)

1988-01-01

This progress report 1986-1987 deals with the first two years operation of the TANDAR electrostatic accelerator and also describes the research work in the following fields: nuclear physics (nuclear structure, nuclear reactions, intermediate energies, applied nuclear physics); solid state physics (crystallography and phase transitions, Mossbauer spectroscopy, condensed matter theory, crystals growth, instrumentation); atomic physics and computational physics. Finally, the staff, a list of publications and activities related to international agencies is included [es

Final analysis and design of a thermal protection system for 8-foot HTST combustor

Science.gov (United States)

Moskowitz, S.

1973-01-01

The cylindrical shell combustor with T-bar supports in the 8-foot HTST at the NASA-Langley Research Center encountered vibratory fatigue cracking over a period of 50-250 tunnel tests within a limited range of the required operating envelope. A preliminary design study provided several suitable thermal protection system designs for the combustor, one of which was a two-pass regenerative type air-cooled omega-shaped segment liner. A final design layout of the omega segment liner was prepared and analyzed for steady-state and transient conditions. The design of a support system for the fuel spray bar assembly was also included. Detail drawings suitable for fabrication purposes were also prepared. Liner design problems defined during the preliminary study included (1) the ingress of gas into the attachment bulb section of the omega segment, (2) the large thermal gradient along the leg of the omega bulb attachment section and, (3) the local peak metal temperature at the radius between the liner ID and the leg of the bulb attachment. These were resolved during the final design task. Analyses of the final design of the omega segment liner indicated that all design goals were met and the design provided the capability of operating over the required test envelope with a life expectancy substantially above the goal of 1500 cycles.

Development and applications of photosensitive device systems to studies of biological and organic materials. Progress report

International Nuclear Information System (INIS)

1984-01-01

The purpose was to develop and improve appropriate experimental techniques to the point where they could be applied to specific classes of biological problems. Progress is reported in the following areas: (1) area detectors; (2) x-ray diffraction studies of membranes; (3) electron transfer in loosely coupled systems; (4) bioluminescence and fluorescence; and (5) sonoluminescence

Tank Waste Remediation System, Hanford Site, Richland, Washington. Final Environmental Impact Statement. Volume IV

International Nuclear Information System (INIS)

1996-08-01

This document, Volume 4, describes the current safety concerns associated with the tank waste and analyzes the potential accidents and associated potential health effects that could occur under the alternatives included in this Tank Waste Remediation System (TWRS) Final Environmental Impact Statement (EIS) for the Hanford Site, Richland, Washington

Hydrologic resources management program, FY 1998 progress report; FINAL

International Nuclear Information System (INIS)

Benedict, F.C.; Criss, R.E.; Davisson, M.L.; Eaton, G.F.; Hudson, G.B.; Kenneally, J.M.; Rose, T.P.; Smith, D.

1999-01-01

This report presents the results from FY 1998 technical studies conducted by Lawrence Livermore National Laboratory (LLNL) as part of the Hydrology and Radionuclide Migration Program (HRMP) and Underground Test Area (UGTA) project. The HRMP is sponsored by Defense Programs (DP) of the U.S. Department of Energy, Nevada Operations Office (DOE/NV), and supports DP operations at the Nevada Test Site (NTS) through studies of radiochemistry and resource management related to the defense programs mission. Other participating organizations include the Los Alamos National Laboratory (LANL), the United States Geological Survey (USGS), the Desert Research Institute (DRI) of the University of Nevada, the United States Environmental Protection Agency (EPA), and Bechtel-Nevada (BN). The UGTA project is an Environmental Management (EM) activity of DOE/NV that supports a Federal Facilities Agreement and Consent Order between the Department of Energy, the Department of Defense, and the State of Nevada. UGTA's primary function is to address the legacy release of hazardous constituents at the Nevada Test Site, the Tonopah Test Range, and off-Nevada Test Site underground nuclear testing areas. Participating contractors include LLNL (Earth and Environmental Sciences Directorate, Analytical and Nuclear Chemistry Division), LANL, DRI, USGS, BN, HSI-GeoTrans, and IT Corporation. The FY 1998 HRMP and UGTA annual progress report follows the organization and contents of our FY 1997 report (Smith et al., 1998), and includes our results from CY 1997-1998 technical studies of radionuclide migration and isotope hydrology at the Nevada Test Site. During FY 1998, LLNL continued its efforts under the HRMP to pursue a technical agenda relevant to the science-based stockpile stewardship program at DOE/NV. Support to UGTA in FY 1998 included efforts to quantitatively define the radionuclide source term residual from underground nuclear weapons testing and the derivative solution, or hydrologic source

Advanced Turbine Systems (ATS) program conceptual design and product development. Quarterly progress report, December 1, 1995--February 29, 1996

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-06-01

This report describes the overall program status of the General Electric Advanced Gas Turbine Development program, and reports progress on three main task areas. The program is focused on two specific products: (1) a 70-MW class industrial gas turbine based on the GE90 core technology, utilizing a new air cooling methodology; and (2) a 200-MW class utility gas turbine based on an advanced GE heavy-duty machine, utilizing advanced cooling and enhancement in component efficiency. The emphasis for the industrial system is placed on cycle design and low emission combustion. For the utility system, the focus is on developing a technology base for advanced turbine cooling while achieving low emission combustion. The three tasks included in this progress report are on: conversion to a coal-fueled advanced turbine system, integrated program plan, and design and test of critical components. 13 figs., 1 tab.

Design and development of progressive tool for manufacturing washer

Science.gov (United States)

Annigeri, Ulhas K.; Raghavendra Ravi Kiran, K.; Deepthi, Y. P.

2017-07-01

In a progressive tool the raw material is worked at different station to finally fabricate the component. A progressive tool is a lucrative tool for mass production of components. A lot of automobile and other transport industries develop progressive tool for the production of components. The design of tool involves lot of planning and the same amount of skill of process planning is required in the fabrication of the tool. The design also involves use of thumb rules and standard elements as per experience gained in practice. Manufacturing the press tool is a laborious task as special jigs and fixtures have to be designed for the purpose. Assembly of all the press tool elements is another task where use of accurate measuring instruments for alignment of various tool elements is important. In the present study, design and fabrication of progressive press tool for production of washer has been developed and the press tool has been tried out on a mechanical type of press. The components produced are to dimensions.

Fused Silica Final Optics for Inertial Fusion Energy: Radiation Studies and System-Level Analysis

International Nuclear Information System (INIS)

Latkowski, Jeffery F.; Kubota, Alison; Caturla, Maria J.; Dixit, Sham N.; Speth, Joel A.; Payne, Stephen A.

2003-01-01

The survivability of the final optic, which must sit in the line of sight of high-energy neutrons and gamma rays, is a key issue for any laser-driven inertial fusion energy (IFE) concept. Previous work has concentrated on the use of reflective optics. Here, we introduce and analyze the use of a transmissive final optic for the IFE application. Our experimental work has been conducted at a range of doses and dose rates, including those comparable to the conditions at the IFE final optic. The experimental work, in conjunction with detailed analysis, suggests that a thin, fused silica Fresnel lens may be an attractive option when used at a wavelength of 351 nm. Our measurements and molecular dynamics simulations provide convincing evidence that the radiation damage, which leads to optical absorption, not only saturates but that a 'radiation annealing' effect is observed. A system-level description is provided, including Fresnel lens and phase plate designs

Biobehavioral Influences on Cancer Progression

Science.gov (United States)

Costanzo, Erin S.; Sood, Anil K.; Lutgendorf, Susan K.

2010-01-01

Synopsis This review focuses on the contributions of stress-related behavioral factors to cancer growth and metastasis and the biobehavioral mechanisms underlying these relationships. We describe behavioral factors that are important in modulation of the stress response and the pivotal role of neuroendocrine regulation in the downstream alteration of physiological pathways relevant to cancer control, including the cellular immune response, inflammation, and tumor angiogenesis, invasion, and cell-signaling pathways. Consequences for cancer progression and metastasis, as well as quality of life, are delineated. Finally, behavioral and pharmacological interventions for cancer patients with the potential to alter these biobehavioral pathways are discussed. PMID:21094927

Neuroimaging classification of progression patterns in glioblastoma: a systematic review.

Science.gov (United States)

Piper, Rory J; Senthil, Keerthi K; Yan, Jiun-Lin; Price, Stephen J

2018-03-30

Our primary objective was to report the current neuroimaging classification systems of spatial patterns of progression in glioblastoma. In addition, we aimed to report the terminology used to describe 'progression' and to assess the compliance with the Response Assessment in Neuro-Oncology (RANO) Criteria. We conducted a systematic review to identify all neuroimaging studies of glioblastoma that have employed a categorical classification system of spatial progression patterns. Our review was registered with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) registry. From the included 157 results, we identified 129 studies that used labels of spatial progression patterns that were not based on radiation volumes (Group 1) and 50 studies that used labels that were based on radiation volumes (Group 2). In Group 1, we found 113 individual labels and the most frequent were: local/localised (58%), distant/distal (51%), diffuse (20%), multifocal (15%) and subependymal/subventricular zone (15%). We identified 13 different labels used to refer to 'progression', of which the most frequent were 'recurrence' (99%) and 'progression' (92%). We identified that 37% (n = 33/90) of the studies published following the release of the RANO classification were adherent compliant with the RANO criteria. Our review reports significant heterogeneity in the published systems used to classify glioblastoma spatial progression patterns. Standardization of terminology and classification systems used in studying progression would increase the efficiency of our research in our attempts to more successfully treat glioblastoma.

[Progress in molecular biology of a semi-mangrove, Millettia pinnata].

Science.gov (United States)

Huang, Jianzi; Zhang, Wanke; Huang, Rongfeng; Zheng, Yizhi

2015-04-01

Millettia pinnata L. is a leguminous tree with great potential in biodiesel applications and also a typical semi-mangrove. In this review, we presented several aspects about the recent research progress in molecular biology of M. pinnata. We descrived several types of molecular markers used to assess the genetic diversity and phylogeny of this species, genome and transcriptome analyses based on high-throughput sequencing platform accomplished for this species, and several gene and genomic sequences of this species isolated for further research. Finally, based on the current research progress, we proposed some orientations for future molecular biology research on M. pinnata.

Conceptual design of bend, compression, and final focus components of ILSE [Induction Linac System Experiment

International Nuclear Information System (INIS)

Lee, E.P.; Fong, C.; Mukherjee, S.; Thur, W.

1989-03-01

The Induction Linac System Experiment (ILSE) includes a 180/degree/ bend system, drift compression line and a final focus, which test the analogous features of a heavy ion driver for inertial fusion. These components are novel in their transport of a space-charge-dominated ion beam with large head-to-tail velocity tilt. Their conceptual design is presented, including calculations of the beam envelope, momentum dispersion, and engineering design of magnets, vacuum system, diagnostics, alignment, and support. 3 refs., 5 figs

Reactor Primary Coolant System Pipe Rupture Study. Progress report No. 32, July--December 1974

International Nuclear Information System (INIS)

1975-03-01

The pipe rupture study is designed to extend the understanding of failure-causing mechanisms and to provide improved capability for evaluating reactor piping systems to minimize the probability of failures. Following a detailed review to determine the effort most needed to improve nuclear system piping (Phase I), analytical and experimental efforts (Phase II) were started in 1965. This progress report summarizes the recent accomplishments of a broad program in (a) basic fatigue studies focused on Elastic/Plastic ASME Code Design Rules, (b) at-reactor tests of the effect of primary coolant environment on the fatigue behavior of piping steels, and (c) studies directed at quantifying weld sensitization in T-304 stainless steel. (auth)

Analytical approach to chromatic correction in the final focus system of circular colliders

Directory of Open Access Journals (Sweden)

Yunhai Cai

2016-11-01

Full Text Available A conventional final focus system in particle accelerators is systematically analyzed. We find simple relations between the parameters of two focus modules in the final telescope. Using the relations, we derive the chromatic Courant-Snyder parameters for the telescope. The parameters are scaled approximately according to (L^{*}/β_{y}^{*}δ, where L^{*} is the distance from the interaction point to the first quadrupole, β_{y}^{*} the vertical beta function at the interaction point, and δ the relative momentum deviation. Most importantly, we show how to compensate its chromaticity order by order in δ by a traditional correction module flanked by an asymmetric pair of harmonic multipoles. The method enables a circular Higgs collider with 2% momentum aperture and illuminates a path forward to 4% in the future.

Final Technical Progress Report

Energy Technology Data Exchange (ETDEWEB)

J.Y. Hwang; R.C. Greenlund

2002-12-31

Michigan Technological University has demonstrated major inroads in establishing the viability of utilizing aluminum smelting by-product waste materials in lightweight concrete product applications. The research identified key elements of producing various forms of lightweight concrete products through utilizing various procedures and mixture components with the by-product materials. A process was developed through pilot plant testing that results in additional aluminum recovery at finer sizes, a clean returnable salt product through spray drying technology, and a low-salt-content oxide product with enough aluminum metal content that it can be used to form lightweight cementitious mixtures. Having three distinct products aids in generating favorable process economics. Revenue projections from aluminum recovery and salt recovery are enough to cover processing costs and create a cost-free oxide product to market for lightweight concrete applications. This supply side commercialization strategy offers aluminum by-product recyclers a potentially no cost product, which has been demonstrated through this project to create desirable and marketable lightweight concrete products of various forms. Environmental benefits to the public are tremendous. At best, all dross and salt cake materials have the potential to be completely recycled and utilized. At worst, disposal sites would see a reduced amount of material: a post processed oxide product with little salt and no hydrogen sulfide or ammonia gas generating capability, which, if isolated from high alkali conditions, would pose no reactivity concerns. The US aluminum industry has historically, along with the steel industry, been a leader in recycling metal. The findings from this project, increased metal recovery, improved salt recycling, and demonstrated end uses for oxide residues, will go a long way in helping the aluminum industry obtain 100% material utilization and zero discharge.

Maryland University sectored isochronous cyclotron (MUSIC): Progress report No. 8

Energy Technology Data Exchange (ETDEWEB)

1966-07-10

Progress is reported in the area of acquiring a magnet frame, coils, and magnet handling equipment. Progress is also reported in relation to the design of the rf system. A detailed account is given of magnet system measurements and rf system studies, as well as studies of the amplifier chain. (LEW)

Pregnancy-induced progression of keratoconus.

Science.gov (United States)

Bilgihan, Kamil; Hondur, Ahmet; Sul, Sabahattin; Ozturk, Sertac

2011-09-01

To report eyes with keratoconus that progressed during pregnancy. Seven eyes of 4 patients with progression of keratoconus during pregnancy were included in this study. The mean age of patients and the mean follow-up duration were 29.3 years and 39 months, respectively. Progressive keratoconus was documented with changes in refraction, corneal topography, and rigid gas-permeable lens fitting pattern. Patients with accompanying systemic and ocular diseases associated with keratoconus, uncontrolled atopic disease, and eye rubbing were excluded. Mean increase in spherical equivalent refraction and simulated keratometry values were 1.4 ± 1.1 and 1.1 ± 0.8 diopters, respectively. In eyes wearing rigid gas-permeable lenses, increase in corneal apical touch and decrease in the base curve radius of the best-fitting contact lens were observed. Hormonal changes during pregnancy may affect corneal biomechanics negatively, and pregnancy may be a previously unrecognized risk factor for progression of keratoconus. To our knowledge, this is the first study showing pregnancy-induced keratoconus progression in patients with no accompanying disease.

Shippingport Station Decommissioning Project (SSDP). A progress report

International Nuclear Information System (INIS)

Mullee, G.R.; Usher, J.M.

1986-01-01

The Shippingport Atomic Power Station was shutdown in October, 1982 by the Plant Operator, Duquesne Light Company, for decommissioning by the US Department of Energy. The planning for decommissioning was completed in September, 1983. In September, 1984 operational responsibility for the station was transferred to the DOE's Decommissioning Operations Contractor - the General Electric Company (assisted by an integrated subcontractor, MK Ferguson Company). Significant accomplishments to date include the completion of all prerequisites for decommissioning, the removal of asbestos from plant systems, loading of irradiated reactor components into the reactor vessel for shipment, the commencement of electrical deactivations and the commencement of piping/component removal. Decontamination and waste processing are progressing in support of the project schedule. The reactor vessel will be shipped as one piece on a barge for burial at Hanford, Washington. The final release of the site is scheduled for April, 1990. A technology transfer program is being utilized to disseminate information about the project

The remuneration system and motivation of employees

OpenAIRE

MATEJOVÁ, Petra

2013-01-01

The remuneration system and motivation of employees are very important part of every company. It is very resisting in how the system is adjusted and if it works not only for company, but for employees as well. The remuneration system together with motivation of employees are better matching with all the processes in company, which are in progress in the company, the final result can be taken for the employees as bigger motivation for the work and they will be worked more effectively, which is...

Solar heating system installed at Telex Communications, Inc. , Blue Earth, Minnesota. Final report

Energy Technology Data Exchange (ETDEWEB)

McEver, William S.

1979-10-26

The final results are summarized of a contract for space heating a 97,000 square foot building which houses administrative offices, assembly areas and warehouse space. Information is also provided on system description, test data, major problems and resolutions, performance, operation and maintenance manual, manufacturer's literature, and as-built drawings. The system began delivering space heating in February 1978. The Telex solar system is composed of four main subsystems; they are the solar collectors, controls, thermal storage and heat distribution. The ITC/Solar Mark III collector was used. The collector array consists of 10 rows of 36 collectors each. The control subsystem controls the operation of the system pumps and control valves. Thermal storage for the system is provided by a 20,000 gallon water storage tank located inside the building. Heating is accomplished by water-to-air heat exchangers and controlled by thermostats.

Progress in markets for grid-connected PV systems in the built environment

International Nuclear Information System (INIS)

Haas, R.

2004-01-01

In the last decade of the twentieth century a wide variety of promotion strategies increased the market penetration of small grid-connected PV systems world-wide. The objective of this paper is to assess the impact of these promotion strategies on the market for and on the economic performance of small grid-connected PV systems. The most important conclusions of this analysis are: Pure cost-effectiveness is not crucial for private customers. Affordability is rather what counts. Non-monetary issues play an important role for a substantial increase in market deployment. Comprehensive accompanied information and education activities are also important along with financial incentives. There are still considerable barriers in the market: on the one hand transparent and competitive markets exist in only a few countries; on the other hand non-monetary transaction costs still represent a major barrier. Progress with respect to cost reduction has been achieved, but mainly for non-module components. (author)

Review of Recent Progress of Plasmonic Materials and Nano-Structures for Surface-Enhanced Raman Scattering

Directory of Open Access Journals (Sweden)

Alan X. Wang

2015-05-01

Full Text Available Surface-enhanced Raman scattering (SERS has demonstrated single-molecule sensitivity and is becoming intensively investigated due to its significant potential in chemical and biomedical applications. SERS sensing is highly dependent on the substrate, where excitation of the localized surface plasmons (LSPs enhances the Raman scattering signals of proximate analyte molecules. This paper reviews research progress of SERS substrates based on both plasmonic materials and nano-photonic structures. We first discuss basic plasmonic materials, such as metallic nanoparticles and nano-rods prepared by conventional bottom-up chemical synthesis processes. Then, we review rationally-designed plasmonic nano-structures created by top-down approaches or fine-controlled synthesis with high-density hot-spots to provide large SERS enhancement factors (EFs. Finally, we discuss the research progress of hybrid SERS substrates through the integration of plasmonic nano-structures with other nano-photonic devices, such as photonic crystals, bio-enabled nanomaterials, guided-wave systems, micro-fluidics and graphene.

Does lowering cholesterol have an impact on the progression of aortic stenosis?

DEFF Research Database (Denmark)

Greve, A.M.; Wachtell, K.

2008-01-01

reviews the pathophysiological mechanisms of calcific AS, reviews current clinical trials of statin use in aortic stenosis and reports on on-going trials, evaluating whether cholesterol lowering therapy can slow disease progression in different populations. Finally, we review if computerized tomography...

EPA's information management system for tracking reasonable further progress. Report for October 1992-May 1993

Energy Technology Data Exchange (ETDEWEB)

Barnard, W.R.; Monroe, C.C.; Dean, T.A.

1993-01-01

The paper describes operating characteristics of a personal-computer (PC)-based Reasonable Further Progress (RFP) tracking system developed for use by EPA to evaluate the progress that nonattainment areas are making toward meeting a 15% volatile organic compound (VOC) reduction specified in the Clean Air Act Amendments (CAAA) of 1990. Details of the program's capabilities, file handling, reporting, and graphics are reported. In order to track the emission reductions resulting from these strategies, emissions reported in the RFP projection inventories will be compared with actual emissions reported in periodic adjusted-base inventories, that are also required by the CAAA. However, the comparison will take place a number of years in the future.

2004 Progress Report

Energy Technology Data Exchange (ETDEWEB)

Batistoni, Paola; De Marco, Francesco; Pieroni, Leonardo [ed.

2005-07-01

Fusion research is undertaken all over the world with the objective of realising an environmentally responsible source of energy with essentially unlimited and widely distributed fuel reserves. The results of the worldwide efforts made in recent years are now embodied in ITER, the International Thermonuclear Experimental Reactor, designed to produce at least 500 MW of fusion power with a power gain of ten. ITER will test for the first time the interaction of fusion plasma physics with power station technology. In this international framework, during 2004 Fusion Technical and Scientific Unit of ENEA obtained important results in several keys areas. At the Frascati Tokamak Upgrade the lower hybrid microwave system was fully exploited to study the generation and control of the plasma current, and the electron cyclotron heating system reached full power (1.5 MW). With the simultaneous injection of the two waves, good energy confinement regimes with internal transport barriers were obtained at the highest plasma densities ever achieved. Advanced scenario regimes were also addressed in the activities of ENEA at JET. The engineering design of the IGNITOR machine was finalised, and significant progress was made in understanding the plasma physics regimes. Among the technology activities, the qualification of the deposition process of a copper liner on carbon fibre composite (CFC) hollow tiles may be mentioned as the most important achievement. This innovative pre brazed casting process is a competitive candidate for the fabrication of the CFCbased ITER divertor components. ENEA participated in the European activity for the definition and production on an industrial scale of an advanced Nb3Sn strand for the ITER superconducting central solenoid and toroidal field coils. Contributions were also made to the design of the final conductor layout and the characterisation tests. Inertial fusion studies continued along the previous lines, namely, the study of the implosion

2004 Progress Report

International Nuclear Information System (INIS)

Batistoni, Paola; De Marco, Francesco; Pieroni, Leonardo

2005-01-01

Fusion research is undertaken all over the world with the objective of realising an environmentally responsible source of energy with essentially unlimited and widely distributed fuel reserves. The results of the worldwide efforts made in recent years are now embodied in ITER, the International Thermonuclear Experimental Reactor, designed to produce at least 500 MW of fusion power with a power gain of ten. ITER will test for the first time the interaction of fusion plasma physics with power station technology. In this international framework, during 2004 Fusion Technical and Scientific Unit of ENEA obtained important results in several keys areas. At the Frascati Tokamak Upgrade the lower hybrid microwave system was fully exploited to study the generation and control of the plasma current, and the electron cyclotron heating system reached full power (1.5 MW). With the simultaneous injection of the two waves, good energy confinement regimes with internal transport barriers were obtained at the highest plasma densities ever achieved. Advanced scenario regimes were also addressed in the activities of ENEA at JET. The engineering design of the IGNITOR machine was finalised, and significant progress was made in understanding the plasma physics regimes. Among the technology activities, the qualification of the deposition process of a copper liner on carbon fibre composite (CFC) hollow tiles may be mentioned as the most important achievement. This innovative pre brazed casting process is a competitive candidate for the fabrication of the CFCbased ITER divertor components. ENEA participated in the European activity for the definition and production on an industrial scale of an advanced Nb3Sn strand for the ITER superconducting central solenoid and toroidal field coils. Contributions were also made to the design of the final conductor layout and the characterisation tests. Inertial fusion studies continued along the previous lines, namely, the study of the implosion

Research on hidden variable theories: A review of recent progresses

Energy Technology Data Exchange (ETDEWEB)

Genovese, Marco [Istituto Elettrotecnico Nazionale Galileo Ferraris, Strada delle Cacce 91, 10135 Torino (Italy)]. E-mail: genovese@ien.it

2005-07-01

Quantum Mechanics (QM) is one of the pillars of modern physics: an impressive amount of experiments have confirmed this theory and many technological applications are based on it. Nevertheless, at one century since its development, various aspects concerning its very foundations still remain to be clarified. Among them, the transition from a microscopic probabilistic world into a macroscopic deterministic one and quantum non-locality. A possible way out from these problems would be if QM represents a statistical approximation of an unknown deterministic theory. This review is addressed to present the most recent progresses on the studies related to hidden variable theories (HVT), both from an experimental and a theoretical point of view, giving a larger emphasis to results with a direct experimental application. More in details, the first part of the review is a historical introduction to this problem. The Einstein-Podolsky-Rosen argument and the first discussions about HVT are introduced, describing the fundamental Bell's proposal for a general experimental test of every local HVT and the first attempts to realise it. The second part of the review is devoted to elucidate the recent progresses toward a conclusive Bell inequalities experiment obtained with entangled photons and other physical systems. Finally, the last sections are targeted to shortly discuss non-local HVT.

CHL1 is involved in human breast tumorigenesis and progression

Energy Technology Data Exchange (ETDEWEB)

He, Li-Hong [Medical Department of Breast Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Ma, Qin [Department of Oncology, The General Hospital of Tianjin Medical University, Tianjin (China); Shi, Ye-Hui [Medical Department of Breast Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Ge, Jie; Zhao, Hong-Meng [Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Breast Surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Li, Shu-Fen [Medical Department of Breast Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Tong, Zhong-Sheng, E-mail: 83352162@qq.com [Medical Department of Breast Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China)

2013-08-23

Highlights: •CHL1 is down-regulation in breast cancer tissues. •Down-regulation of CHL1 is related to high grade. •Overexpression of CHL1 inhibits breast cancer cell proliferation and invasion in vitro. •CHL1 deficiency induces breast cancer cell proliferation and invasion both in vitro and in vivo. -- Abstract: Neural cell adhesion molecules (CAM) play important roles in the development and regeneration of the nervous system. The L1 family of CAMs is comprised of L1, Close Homolog of L1 (CHL1, L1CAM2), NrCAM, and Neurofascin, which are structurally related trans-membrane proteins in vertebrates. Although the L1CAM has been demonstrated play important role in carcinogenesis and progression, the function of CHL1 in human breast cancer is limited. Here, we found that CHL1 is down-regulated in human breast cancer and related to lower grade. Furthermore, overexpression of CHL1 suppresses proliferation and invasion in MDA-MB-231 cells and knockdown of CHL1 expression results in increased proliferation and invasion in MCF7 cells in vitro. Finally, CHL1 deficiency promotes tumor formation in vivo. Our results may provide a strategy for blocking breast carcinogenesis and progression.

CHL1 is involved in human breast tumorigenesis and progression

International Nuclear Information System (INIS)

He, Li-Hong; Ma, Qin; Shi, Ye-Hui; Ge, Jie; Zhao, Hong-Meng; Li, Shu-Fen; Tong, Zhong-Sheng

2013-01-01

Highlights: •CHL1 is down-regulation in breast cancer tissues. •Down-regulation of CHL1 is related to high grade. •Overexpression of CHL1 inhibits breast cancer cell proliferation and invasion in vitro. •CHL1 deficiency induces breast cancer cell proliferation and invasion both in vitro and in vivo. -- Abstract: Neural cell adhesion molecules (CAM) play important roles in the development and regeneration of the nervous system. The L1 family of CAMs is comprised of L1, Close Homolog of L1 (CHL1, L1CAM2), NrCAM, and Neurofascin, which are structurally related trans-membrane proteins in vertebrates. Although the L1CAM has been demonstrated play important role in carcinogenesis and progression, the function of CHL1 in human breast cancer is limited. Here, we found that CHL1 is down-regulated in human breast cancer and related to lower grade. Furthermore, overexpression of CHL1 suppresses proliferation and invasion in MDA-MB-231 cells and knockdown of CHL1 expression results in increased proliferation and invasion in MCF7 cells in vitro. Finally, CHL1 deficiency promotes tumor formation in vivo. Our results may provide a strategy for blocking breast carcinogenesis and progression

Research on hidden variable theories: A review of recent progresses

International Nuclear Information System (INIS)

Genovese, Marco

2005-01-01

Quantum Mechanics (QM) is one of the pillars of modern physics: an impressive amount of experiments have confirmed this theory and many technological applications are based on it. Nevertheless, at one century since its development, various aspects concerning its very foundations still remain to be clarified. Among them, the transition from a microscopic probabilistic world into a macroscopic deterministic one and quantum non-locality. A possible way out from these problems would be if QM represents a statistical approximation of an unknown deterministic theory. This review is addressed to present the most recent progresses on the studies related to hidden variable theories (HVT), both from an experimental and a theoretical point of view, giving a larger emphasis to results with a direct experimental application. More in details, the first part of the review is a historical introduction to this problem. The Einstein-Podolsky-Rosen argument and the first discussions about HVT are introduced, describing the fundamental Bell's proposal for a general experimental test of every local HVT and the first attempts to realise it. The second part of the review is devoted to elucidate the recent progresses toward a conclusive Bell inequalities experiment obtained with entangled photons and other physical systems. Finally, the last sections are targeted to shortly discuss non-local HVT

Tc-99m-bicisate (ECD)-brain-SPECT in rapidly progressive dementia

International Nuclear Information System (INIS)

Marienhagen, J.; Eilles, C.; Weingaertner, U.; Blaha, L.; Zerr, I.; Poser, S.

1999-01-01

We present a 61-year-old male patient with progressive dementia. A brain SPECT with Tc-99m-bicisate was performed for confirmation of clinically suspected Alzheimer-dementia. At the time of the SPECT-investigation marked apraxia and aphasia besides severe dementia were present. Electrophysiological as well as anatomical neuroimaging findings showed non-diagnostic alterations. SPECT revealed distinct perfusion defects, which made Alzheimer Dementia unlikely. The further course of the patient was determined by rapidly progressive deterioration with development of akinetic mutism. Thereafter, increased levels of neuron-specific enolase as well as 14-3-3 proteins were found in the cerebro-spinal fluid (CSF). The patient finally died with signs of cerebral decortication. Due to the clinical course and the CSF-findings the patient's final diagnosis was Creutzfeld-Jakob-disease, nevertheless no autopsy was performed. The presented case report underscores the clinical utility of perfusion brain SPECT in the differential diagnosis of dementias. (orig.) [de

Progress in the RAMI analysis of a conceptual LHCD system for DEMO

Science.gov (United States)

Mirizzi, F.

2014-02-01

Reliability, Availability, Maintainability and Inspectability (RAMI) concepts and techniques, that acquired great importance during the first manned space missions, have been progressively extended to industrial, scientific and consumer equipments to assure them satisfactory performances and lifetimes. In the design of experimental facilities, like tokamaks, mainly aimed at demonstrating validity and feasibility of scientific theories, RAMI analysis has been often left aside. DEMO, the future prototype fusion reactors, will be instead designed for steadily delivering electrical energy to commercial grids, so that the RAMI aspects will assume an absolute relevance since their initial design phases. A preliminary RAMI analysis of the LHCD system for the conceptual EU DEMO reactor is given in the paper.

Progress in the RAMI analysis of a conceptual LHCD system for DEMO

International Nuclear Information System (INIS)

Mirizzi, F.

2014-01-01

Reliability, Availability, Maintainability and Inspectability (RAMI) concepts and techniques, that acquired great importance during the first manned space missions, have been progressively extended to industrial, scientific and consumer equipments to assure them satisfactory performances and lifetimes. In the design of experimental facilities, like tokamaks, mainly aimed at demonstrating validity and feasibility of scientific theories, RAMI analysis has been often left aside. DEMO, the future prototype fusion reactors, will be instead designed for steadily delivering electrical energy to commercial grids, so that the RAMI aspects will assume an absolute relevance since their initial design phases. A preliminary RAMI analysis of the LHCD system for the conceptual EU DEMO reactor is given in the paper

Contributions of Behavioral Systems Science to Leadership for a New Progressive Movement.

Science.gov (United States)

Mattaini, Mark A; Aspholm, Roberto

2016-05-01

We argue in this paper that we are in the midst of a period in which fundamental global change will be required if societies and many species, perhaps even our own, are to survive. The realities are inescapable, and the potential implications are likely to affect nearly every dimension of human life in the USA and globally. Current trends are discouraging and will be extraordinarily difficult to shift, given global structural realities. It is hard to imagine a time when effective leadership is more necessary or will be more challenging. Our thesis here is that behavioral systems science can contribute in meaningful ways to shaping and sustaining such leadership, leadership required to advance a new progressive movement.

The AP600 advanced simplified nuclear power plant. Results of the test program and progress made toward final design approval

International Nuclear Information System (INIS)

Bruschi, H.J.

1996-01-01

At the 1994 Pacific Basin Conference, Mr. Bruschi presented a paper describing the AP600, Westinghouse's advanced light water reactor design with passive safety features. Since then, a rigorous test program was completed and AP600 became the most thoroughly tested advanced reactor system design in history. Westinghouse is now well on its way toward receiving Final Design Approval from the U.S. Nuclear Regulatory Commission for AP600. In this paper, the results of the test program will be discussed and an update on prospects for building the plant will be covered. (author)

The AP600 advanced simplified nuclear power plant. Results of the test program and progress made toward final design approval

Energy Technology Data Exchange (ETDEWEB)

Bruschi, H.J. [Westinghouse Electric Corp., Pittsburgh, PA (United States)

1996-10-01

At the 1994 Pacific Basin Conference, Mr. Bruschi presented a paper describing the AP600, Westinghouse`s advanced light water reactor design with passive safety features. Since then, a rigorous test program was completed and AP600 became the most thoroughly tested advanced reactor system design in history. Westinghouse is now well on its way toward receiving Final Design Approval from the U.S. Nuclear Regulatory Commission for AP600. In this paper, the results of the test program will be discussed and an update on prospects for building the plant will be covered. (author)

Electron beam final focus system for Thomson scattering at ELBE

Energy Technology Data Exchange (ETDEWEB)

Krämer, J.M., E-mail: jmkr@danfysik.dk [Danfysik A/S, Gregersensvej 8, 2630 Taastrup (Denmark); Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiation Physics, Bautzner Landstrasse 400, 01328 Dresden (Germany); Technische Universität Dresden, 01069 Dresden (Germany); Budde, M.; Bødker, F. [Danfysik A/S, Gregersensvej 8, 2630 Taastrup (Denmark); Irman, A.; Jochmann, A. [Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiation Physics, Bautzner Landstrasse 400, 01328 Dresden (Germany); Kristensen, J.P. [Danfysik A/S, Gregersensvej 8, 2630 Taastrup (Denmark); Lehnert, U.; Michel, P. [Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiation Physics, Bautzner Landstrasse 400, 01328 Dresden (Germany); Schramm, U. [Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiation Physics, Bautzner Landstrasse 400, 01328 Dresden (Germany); Technische Universität Dresden, 01069 Dresden (Germany)

2016-09-11

The design of an electron beam final focus system (FFS) aiming for high-flux laser-Thomson backscattering X-ray sources at ELBE is presented. A telescope system consisting of four permanent magnet based quadrupoles was found to have significantly less chromatic aberrations than a quadrupole doublet or triplet as commonly used. Focusing properties like the position of the focal plane and the spot size are retained for electron beam energies between 20 and 30 MeV by adjusting the position of the quadrupoles individually on a motorized stage. The desired ultra-short electron bunches require an increased relative energy spread up to a few percent and, thus, second order chromatic effects must be taken into account. We also present the design and test results of the permanent magnet quadrupoles. Adjustable shunts allow for correction of the field strength and compensation of deviations in the permanent magnet material. For a beam emittance of 13 mm mrad, we predict focal spot sizes of about 40 μm (rms) and divergences of about 10 mrad using the FFS.

Electron beam final focus system for Thomson scattering at ELBE

CERN Document Server

Krämer, J.M.; Bødker, F.; Irman, A.; .Jochmann A.; Kristensen, J.P.; Lehnert U., HZDR; Michel, P.; Schrammb, U.; 10.1016/j.nima.2015.10.067

2016-01-01

The design of an electron beam final focus system (FFS) aiming for high-flux laser-Thomson backscattering X-ray sources at ELBE is presented. A telescope system consisting of four permanent magnet based quadrupoles was found to have significantly less chromatic aberrations than a quadrupole doublet or triplet as commonly used. Focusing properties like the position of the focal plane and the spot size are retained for electron beam energies between 20 and 30 MeV by adjusting the position of the quadrupoles individually on a motorized stage. The desired ultra-short electron bunches require an increased relative energy spread up to a few percent and, thus, second order chromatic effects must be taken into account. We also present the design and test results of the permanent magnet quadrupoles. Adjustable shunts allow for correction of the field strength and compensation of deviations in the permanent magnet material. For a beam emittance of 13 mm mrad, we predict focal spot sizes of about 40 μm (rms) and diverg...

Electron Beam Final Focus System For Thomson Scattering At Elbe

CERN Document Server

Krämer, J.M.; Bødkera, F.; Irman, A.; Jochmann, A.; Kristensena, J.P.; Lehnert, U.; Michel, P.; Schramm, U.; 10.1016/j.nima.2015.10.067

2016-01-01

The design of an electron beam final focus system (FFS) aiming for high-flux laser-Thomson backscattering X-ray sources at ELBE is presented. A telescope system consisting of four permanent magnet based quadrupoles was found to have significantly less chromatic aberrations than a quadrupole doublet or triplet as commonly used. Focusing properties like the position of the focal plane and the spot size are retained for electron beam energies between 20 and 30 MeV by adjusting the position of the quadrupoles individually on a motorized stage. The desired ultra-short electron bunches require an increased relative energy spread up to a few percent and, thus, second order chromatic effects must be taken into account. We also present the design and test results of the permanent magnet quadrupoles. Adjustable shunts allow for correction of the field strength and compensation of deviations in the permanent magnet material. For a beam emittance of 13 mm mrad, we predict focal spot sizes of about 40 μm (rms) and diverg...

Final focus system tuning studies towards Compact Linear Collider feasibility

Science.gov (United States)

Marin, E.; Latina, A.; Tomás, R.; Schulte, D.

2018-01-01

In this paper we present the latest results regarding the tuning study of the baseline design of the final focus system of the Compact Linear Collider (CLIC-FFS). CLIC aims to provide collisions to the experiments at a luminosity above 1034 c m-2 s-1 . In order to deliver such luminosity in a single pass machine, the vertical beam size at the interaction point (IP) is reduced to about 1 nm, which imposes unprecedented tuning difficulties to the system. In previous studies, 90% of the machines reached 90% of the nominal luminosity at the expense of 18 000 luminosity measurements, when considering beam position monitor errors and transverse misalignments of magnets for a single beam case. In the present study, additional static imperfections as, roll misalignments, strength v2.epss are included. Moreover both e- and e+ beamlines are properly simulated. A new tuning procedure based on linear and nonlinear knobs is implemented to effectively cure the most relevant beam size aberrations at the IP. The obtained results for single and double beam studies under solely static imperfections are presented.

Acoustic Resonance Spectroscopy (ARS) Munition Classification System enhancements. Final report

Energy Technology Data Exchange (ETDEWEB)

Vela, O.A.; Huggard, J.C.

1997-09-18

Acoustic Resonance Spectroscopy (ARS) is a non-destructive evaluation technology developed at the Los Alamos National Laboratory (LANL). This technology has resulted in three generations of instrumentation, funded by the Defense Special Weapons Agency (DSWA), specifically designed for field identification of chemical weapon (CW) munitions. Each generation of ARS instrumentation was developed with a specific user in mind. The ARS1OO was built for use by the U.N. Inspection Teams going into Iraq immediately after the Persian Gulf War. The ARS200 was built for use in the US-Russia Bilateral Chemical Weapons Treaty (the primary users for this system are the US Onsite Inspection Agency (OSIA) and their Russian counterparts). The ARS300 was built with the requirements of the Organization for the Prohibition of Chemical Weapons (OPCW) in mind. Each successive system is an improved version of the previous system based on learning the weaknesses of each and, coincidentally, on the fact that more time was available to do a requirements analysis and the necessary engineering development. The ARS300 is at a level of development that warrants transferring the technology to a commercial vendor. Since LANL will supply the computer software to the selected vendor, it is possible for LANL to continue to improve the decision algorithms, add features where necessary, and adjust the user interface before the final transfer occurs. This paper describes the current system, ARS system enhancements, and software enhancements. Appendices contain the Operations Manual (software Version 3.01), and two earlier reports on enhancements.

Development and fabrication of a dragline training system. Technical progress report, No. 1 (phase 1 final report)

Energy Technology Data Exchange (ETDEWEB)

Voss, William J.

1979-09-17

As a result of the task analysis and revision to the plan of instruction, certain desirable characteristics were recommended to be added to the dragline trainer. These essentially would provide for a high quality feedback and hard copy record of the trainee's performance. It was recommended that the trainer be able to produce and/or sense and record: drag and hoist over-spooling, dragchain/cone contact, bucket shock, bucket stall, lateral boom stress, tight lining, excessive rapid braking and reaction times to internal/external alarms. In addition, data such as cycle time, bucket position, yardage moved and cycles completed should be recorded and records printed. With the exception of drag chain and cone contact indications, these characteristics can be implemented in the computer program. In some cases, such as bucket stall and external alarms it will require instructor initiative to activate specific trainer scenario and reaction time measurements. It should be noted that these additional features, however desirable, add significantly to the required computer capability. Both processor cycle time and memory availability could be restraints. A faster, and larger system could accommodate these added features but at an increase in cost for the computer system. A study is in process and specific recommendations will result.

Development, Demonstration, and Field Testing of Enterprise-Wide Distributed Generation Energy Management System: Final Report

Energy Technology Data Exchange (ETDEWEB)

Greenberg, S.; Cooley, C.

2005-01-01

This report details progress on subcontract NAD-1-30605-1 between the National Renewable Energy Laboratory and RealEnergy (RE), the purpose of which is to describe RE's approach to the challenges it faces in the implementation of a nationwide fleet of clean cogeneration systems to serve contemporary energy markets. The Phase 2 report covers: utility tariff risk and its impact on market development; the effect on incentives on distributed energy markets; the regulatory effectiveness of interconnection in California; a survey of practical field interconnection issues; trend analysis for on-site generation; performance of dispatch systems; and information design hierarchy for combined heat and power.

Progress on Protection Strategies to Mitigate the Impact of Renewable Distributed Generation on Distribution Systems

Directory of Open Access Journals (Sweden)

Mohamad Norshahrani

2017-11-01

Full Text Available The benefits of distributed generation (DG based on renewable energy sources leads to its high integration in the distribution network (DN. Despite its well-known benefits, mainly in improving the distribution system reliability and security, there are challenges encountered from a protection system perspective. Traditionally, the design and operation of the protection system are based on a unidirectional power flow in the distribution network. However, the integration of distributed generation causes multidirectional power flows in the system. Therefore, the existing protection systems require some improvement or modification to address this new feature. Various protection strategies for distribution system have been proposed so that the benefits of distributed generation can be fully utilized. This paper reviews the current progress in protection strategies to mitigate the impact of distributed generation in the distribution network. In general, the reviewed strategies in this paper are divided into: (1 conventional protection systems and (2 modifications of the protection systems. A comparative study is presented in terms of the respective benefits, shortcomings and implementation cost. Future directions for research in this area are also presented.

Superconducting quadrupoles for the SLC final focus

International Nuclear Information System (INIS)

Erickson, R.; Fieguth, T.; Murray, J.J.

1987-01-01

The final focus system of the SLC will be upgraded by replacing the final quadrupoles with higher gradient superconducting magnets positioned closer to the interaction point. The parameters of the new system have been chosen to be compatible with the experimental detectors with a minimum of changes to other final focus components. These parameter choices are discussed along with the expected improvement in SLC performance

Superconducting quadrupoles for the SLC final focus

International Nuclear Information System (INIS)

Erickson, R.; Fieguth, T.; Murray, J.J.

1987-01-01

The final focus system of the SLC will be upgraded by replacing the final quadrupoles with higher gradient supperconducting magnets positioned closer to the interaction point. The parameters of the new system have been chosen to be compatible with the experimental detectors with a minimum of changes to other final focus components. These parameter choices are discussed along with the expected improvement in SLC performance

Recent progress on the Los Alamos Aurora ICF [inertial confinement fusion] laser system

International Nuclear Information System (INIS)

Rosocha, L.A.; Blair, L.S.

1987-01-01

Aurora is the Los Alamos short-pulse, high-power, krypton-fluoride laser system. It serves as an end-to-end technology demonstration prototype for large-scale ultraviolet laser systems for short wavelength inertial confinement fusion (ICF) investigations. The system is designed to employ optical angular multiplexing and serial amplification by electron-beam-driven KrF laser amplifiers to deliver stacked, 248-nm, 5-ns duration multikilojoule laser pulses to ICF-relevant targets. This paper presents a summary of the Aurora system and a discussion of the progress achieved in the construction and integration of the laser system. We concentrate on the main features of the following major system components: front-end lasers, amplifier train, multiplexer, optical relay train, demultiplexer, and the associated optical alignment system. During the past year, two major construction and integration tasks have been accomplished. The first task is the demonstration of 96-beam multiplexing and amplified energy extraction, as evidenced by the integrated operation of the front end, the multiplexer (12-fold and 8-fold encoders), the optical relay train, and three electron-beam-driven amplifiers. The second task is the assembly and installation of the demultiplexer optical hardware, which consists of over 300 optical components ranging in size from several centimeters square to over a meter square. 13 refs., 13 figs

Progress and challenges in the development and qualification of multi-level multi-physics coupled methodologies for reactor analysis

International Nuclear Information System (INIS)

Ivanov, K.; Avramova, M.

2007-01-01

Current trends in nuclear power generation and regulation as well as the design of next generation reactor concepts along with the continuing computer technology progress stimulate the development, qualification and application of multi-physics multi-scale coupled code systems. The efforts have been focused on extending the analysis capabilities by coupling models, which simulate different phenomena or system components, as well as on refining the scale and level of detail of the coupling. This paper reviews the progress made in this area and outlines the remaining challenges. The discussion is illustrated with examples based on neutronics/thermohydraulics coupling in the reactor core modeling. In both fields recent advances and developments are towards more physics-based high-fidelity simulations, which require implementation of improved and flexible coupling methodologies. First, the progresses in coupling of different physics codes along with the advances in multi-level techniques for coupled code simulations are discussed. Second, the issues related to the consistent qualification of coupled multi-physics and multi-scale code systems for design and safety evaluation are presented. The increased importance of uncertainty and sensitivity analysis are discussed along with approaches to propagate the uncertainty quantification between the codes. The incoming OECD LWR Uncertainty Analysis in Modeling (UAM) benchmark is the first international activity to address this issue and it is described in the paper. Finally, the remaining challenges with multi-physics coupling are outlined. (authors)

Progress and challenges in the development and qualification of multi-level multi-physics coupled methodologies for reactor analysis

Energy Technology Data Exchange (ETDEWEB)

Ivanov, K.; Avramova, M. [Pennsylvania State Univ., University Park, PA (United States)

2007-07-01

Current trends in nuclear power generation and regulation as well as the design of next generation reactor concepts along with the continuing computer technology progress stimulate the development, qualification and application of multi-physics multi-scale coupled code systems. The efforts have been focused on extending the analysis capabilities by coupling models, which simulate different phenomena or system components, as well as on refining the scale and level of detail of the coupling. This paper reviews the progress made in this area and outlines the remaining challenges. The discussion is illustrated with examples based on neutronics/thermohydraulics coupling in the reactor core modeling. In both fields recent advances and developments are towards more physics-based high-fidelity simulations, which require implementation of improved and flexible coupling methodologies. First, the progresses in coupling of different physics codes along with the advances in multi-level techniques for coupled code simulations are discussed. Second, the issues related to the consistent qualification of coupled multi-physics and multi-scale code systems for design and safety evaluation are presented. The increased importance of uncertainty and sensitivity analysis are discussed along with approaches to propagate the uncertainty quantification between the codes. The incoming OECD LWR Uncertainty Analysis in Modeling (UAM) benchmark is the first international activity to address this issue and it is described in the paper. Finally, the remaining challenges with multi-physics coupling are outlined. (authors)

One System Integrated Project Team Progress in Coordinating Hanford Tank Farms and the Waste Treatment Plant

International Nuclear Information System (INIS)

Skwarek, Raymond J.; Harp, Ben J.; Duncan, Garth M.

2013-01-01

The One System Integrated Project Team (IPT) was formed at the Hanford Site in late 2011 as a way to improve coordination and itegration between the Hanford Tank Waste Treatment and Immobilization Plant (WTP) and the Tank Operations Contractor (TOC) on interfaces between the two projects, and to eliminate duplication and exploit opportunities for synergy. The IPT is composed of jointly staffed groups that work on technical issues of mutal interest, front-end design and project definition, nuclear safety, plant engineering system integration, commissioning, planning and scheduling, and environmental, safety, health and quality (ESH&Q) areas. In the past year important progress has been made in a number of areas as the organization has matured and additional opportunities have been identified. Areas covered in this paper include: Support for development of the Office of Envirnmental Management (EM) framework document to progress the Office of River Protection's (ORP) River Protection Project (RPP) mission; Stewardship of the RPP flowsheet; Collaboration with Savannah River Site (SRS), Savannah River National Laboratory (SRNL), and Pacific Northwest National Laboratory (PNNL); Operations programs integration; and, Further development of the waste acceptance criteria

A simulation of 'schedule-cost' progress monitoring system in nuclear power project management

International Nuclear Information System (INIS)

Song Haitao; Huang Zhongping; Zhang Zemin; Wang Zikai

2010-01-01

The objective of project management is to find the optimal balance between progress and cost according to the project requirements. Traditional method always manages progress and cost separately. However, domestic and international experience indicated that the interactions between these two factors are crucial in the project implementation. Modern project managers have to manage and maintain a 'Progress - Cost' joint control framework. Such a model is applied into a sub-project of a nuclear power project using Simulink in this paper. It helps to identify and correct the deviations of the project. Earned Value Management is used by the project manager to quantify the cost of the project and progress of implementation. The budget plan value, actual value, earned value are three important parameters to measure cost and progress of the project. The experimental results illustrated that the method gives a more comprehensive performance evaluation of the project. (authors)

Tax System in Poland – Progressive or Regressive?

Directory of Open Access Journals (Sweden)

Jacek Tomkiewicz

2016-03-01

Full Text Available Purpose: To analyse the impact of the Polish fiscal regime on the general revenue of the country, and specifically to establish whether the cumulative tax burden borne by Polish households is progressive or regressive.Methodology: On the basis of Eurostat and OECD data, the author has analysed fiscal regimes in EU Member States and in OECD countries. The tax burden of households within different income groups has also been examined pursuant to applicable fiscal laws and data pertaining to the revenue and expenditure of households published by the Central Statistical Office (CSO.Conclusions: The fiscal regime in Poland is regressive; that is, the relative fiscal burden decreases as the taxpayer’s income increases.Research Implications: The article contributes to the on-going discussion on social cohesion, in particular with respect to economic policy instruments aimed at the redistribution of income within the economy.Originality: The author presents an analysis of data pertaining to fiscal policies in EU Member States and OECD countries and assesses the impact of the legal environment (fiscal regime and social security system in Poland on income distribution within the economy. The impact of the total tax burden (direct and indirect taxes, social security contributions on the economic situation of households from different income groups has been calculated using an original formula.

[Research progress on a nanodrug delivery system for prevention and control of dental caries and periodontal diseases].

Science.gov (United States)

Yaling, Jiang; Mingye, Feng; Lei, Cheng

2017-02-01

Dental caries and periodontal diseases are common chronic infectious diseases that cause serious damage to oral health. Bacteria is the primary factor leading to such conditions. As a dental plaque control method, chemotherapeutic agents face serious challenges in dental care because of the specific physiological and anatomical characteristics of the oral cavity. Nanodrug delivery system is a series of new drug delivery systems at nanoscale, and it can target cells, promote sustainedrelease effects, and enhance biodegradation. This review focuses on research progress on nanodrug delivery systems for prevention and control of dental caries and periodontal diseases.

Progress in nanophotonics 1

CERN Document Server

Ohtsu, Motoichi

2011-01-01

This book focuses on the recent progress in nanophotonics technology to be used to develop novel nano-optical devices, fabrication technology, and security systems. It begins with a review of the concept of dressed photons and applications to devices, fabrication, and systems; principles and applications. Further topics include: DNA process for quantum dot chain, photon enhanced emission microscopy, near field spectroscopy of metallic nanostructure, self-organized fabrication of composite semiconductor quantum dots, formation of metallic nanostructure, and nanophotonic information systems with

[Charles Darwin and the problem of evolutionary progress].

Science.gov (United States)

Iordanskiĭ, N N

2010-01-01

According to Ch. Darwin's evolutionary theory, evolutionary progress (interpreted as morpho-physiological progress or arogenesis in recent terminology) is one of logical results of natural selection. At the same time, natural selection does not hold any factors especially promoting evolutionary progress. Darwin emphasized that the pattern of evolutionary changes depends on organism nature more than on the pattern of environment changes. Arogenesis specificity is determined by organization of rigorous biological systems - integral organisms. Onward progressive development is determined by fundamental features of living organisms: metabolism and homeostasis. The concept of social Darwinism differs fundamentally from Darwin's ideas about the most important role of social instincts in progress of mankind. Competition and selection play secondary role in socio-cultural progress of human society.

Comparative Study of the Tuning Performances of the Nominal and Long L* CLIC Final Focus System at √s = 380 GeV

CERN Document Server

Plassard, F; Marin, E; Tomás, R

2017-01-01

Mitigation of static imperfections for emittance preservation is one of the most important and challenging tasks faced by the Compact Linear Collider (CLIC) beam delivery system. A simulation campaign has been performed to recover the nominal luminosity by means of different alignment procedures. The state of the art of the tuning studies is drawn up. Comparative studies of the tuning performances and a tuning-based final focus system design optimization for two L options are presented. The effectiveness of the tuning techniques applied to these different lattices will be decisive for the final layout of the CLIC final focus system at √s = 380 GeV.

Progress of JPDR decommissioning project

International Nuclear Information System (INIS)

Kiyota, M.; Yanagihara, S.

1995-01-01

The Japan Power Demonstration Reactor (JPDR) decommissioning project is progressively achieving its final goal; the project will be finished by March 1996 to release the JPDR's site into unrestricted use in a green field condition. The new techniques which developed or improved in R and D, the first phase of this program, have been successfully applied to the actual dismantling activities. Some decommissioning wastes have been managed as the first case of onsite shallow land burial based on the new regulatory frame of radioactive waste management. The experiences and the data obtained from the JPDR dismantling activities are expected to contribute to future decommissioning of commercial nuclear power plants. (author)

The Pennsylvania State University Light Water Ultra-Safe Plant Concept: 3rd quarter progress report

International Nuclear Information System (INIS)

Klevans, E.

1987-01-01

Progress in the Ultra Safe study has substantially increased since the last report. The search for pressurizing pump turbine component information is now complete and a final plant layout for detailed evaluation has been chosen. Significant results for the normal operation performance of the Ultra Safe pressurizing technique are included. The plan of attack for the evaluation of the Ultra Safe shutdown scenario and natural circulation capability is discussed. This process is expected to be the next key area for analysis. The reactor design is complete including a change to alleviate the need for a soluble boron system. Material on the reactor building layout is also provided

[Specificities of the logopenic variant of primary progressive aphasia].

Science.gov (United States)

Magnin, E; Teichmann, M; Martinaud, O; Moreaud, O; Ryff, I; Belliard, S; Pariente, J; Moulin, T; Vandel, P; Démonet, J-F

2015-01-01

The logopenic variant of primary progressive aphasia is a syndrome with neuropsychological and linguistic specificities, including phonological loop impairment for which diagnosis is currently mainly based on the exclusion of the two other variants, semantic and nonfluent/agrammatic primary progressive aphasia. The syndrome may be underdiagnosed due (1) to mild language difficulties during the early stages of the disease or (2) to being mistaken for mild cognitive impairment or Alzheimer's disease when the evaluation of episodic memory is based on verbal material and (3) finally, it is not uncommon that the disorders are attributed to psychiatric co-morbidities such as, for example, anxiety. Moreover, compared to other variants of primary progressive aphasia, brain abnormalities are different. The left temporoparietal junction is initially affected. Neuropathology and biomarkers (cerebrospinal fluid, molecular amyloid nuclear imaging) frequently reveal Alzheimer's disease. Consequently this variant of primary progressive aphasia does not fall under the traditional concept of frontotemporal lobar degeneration. These distinctive features highlight the utility of correct diagnosis, classification, and use of biomarkers to show the neuropathological processes underlying logopenic primary progressive aphasia. The logopenic variant of primary progressive aphasia is a specific form of Alzheimer's disease frequently presenting a rapid decline; specific linguistic therapies are needed. Further investigation of this syndrome is needed to refine screening, improve diagnostic criteria and better understand the epidemiology and the biological mechanisms involved. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Experimental Program Final Technical Progress Report: 15 February 2007 to 30 September 2012

Energy Technology Data Exchange (ETDEWEB)

Kinney, Edward R. [University of Colorado, Boulder, CO

2014-09-12

This is the final technical report of the grant DE-FG02-04ER41301 to the University of Colorado at Boulder entitled "Intermediate Energy Nuclear Physics" and describes the results of our funded activities during the period 15 February 2007 to 30 September 2012. These activities were primarily carried out at Fermilab, RHIC, and the German lab DESY. Significant advances in these experiments were carried out by members of the Colorado group and are described in detail.

Superplastic forming and diffusion bonding: Progress and trends

Directory of Open Access Journals (Sweden)

Zhiqiang Li

2015-01-01

Full Text Available This paper summarized recent progress in metal superplasticity and the application of Superplastic Forming/Diffusion Bonding (SPF/DB or SPF/Welding in typical structures. Various aerospace components such as three dimensional lattice structures made by SPF/DB have been demonstrated. In addition, some newly developed technologies, such as melt droplet spreading/thermo-mechanical forming (MDS/TMF, were also included. Finally, the future potential of SPF/DB technology was predicted.

Final focus test beam

International Nuclear Information System (INIS)

1991-03-01

This report discusses the following: the Final Focus Test Beam Project; optical design; magnets; instrumentation; magnetic measurement and BPM calibration; mechanical alignment and stabilization; vacuum system; power supplies; control system; radiation shielding and personnel protection; infrastructure; and administration

Progress Toward Heavy Ion IFE

International Nuclear Information System (INIS)

Meier, W.R.; Logan, B.G.; Waldron, W.L.; Sabbi, G.L.; Callahan-Miller, D.A.; Peterson, P.F.; Goodin, D.T.

2002-01-01

Successful development of Heavy Ion Fusion (HIF) will require scientific and technology advances in areas of targets, drivers and chambers. Design work on heavy ion targets indicates that high gain (60-130) may be possible with a -3-6 MJ driver depending on the ability to focus the beams to small spot sizes. Significant improvements have been made on key components of heavy ion drivers, including sources, injectors, insulators and ferromagnetic materials for long-pulse induction accelerator cells, solid-state pulsers, and superconducting quadrupole magnets. The leading chamber concept for HIF is the thick-liquid-wall HYLEE-II design, which uses an array of flibe jets to protect chamber structures from x-ray, debris, and neutron damage. Significant progress has been made in demonstrating the ability to create and control the types of flow needed to form the protective liquid blanket. Progress has also been made on neutron shielding for the final focus magnet arrays with predicted lifetimes now exceeding the life of the power plant. Safety analyses have been completed for the HYLEE-II design using state-of-the-art codes. Work also continues on target fabrication and injection for HE. A target injector experiment capable of > 5 Hz operation has been designed and construction will start in 2002. Methods for mass production of hohlraum targets are being evaluated with small-scale experiments and analyses. Progress in these areas will be reviewed

Progress toward heavy-ion IFE

International Nuclear Information System (INIS)

Meier, W.R.; Logan, B.G.; Waldron, W.L.; Sabbi, G.-L.; Callahan, D.A.; Peterson, P.F.; Goodin, D.T.

2002-01-01

Successful development of heavy-ion fusion (HIF) will require scientific and technology advances in areas of targets, drivers and chambers. Design work on heavy-ion targets indicates that high gain (60-130) may be possible with a ∼3-6 MJ driver depending on the ability to focus the beams to small spot sizes. Significant improvements have been made on key components of heavy-ion drivers, including sources, injectors, insulators and ferromagnetic materials for long-pulse induction accelerator cells, solid-state pulsers, and superconducting quadrupole magnets. The leading chamber concept for HIF is the thick-liquid-wall HYLIFE-II design, which uses an array of flibe jets to protect chamber structures from X-ray, debris, and neutron damage. Significant progress has been made in demonstrating the ability to create and control the types of flow needed to form the protective liquid blanket. Progress has also been made on neutron shielding for the final focus magnet arrays with predicted lifetimes now exceeding the life of the power plant. Safety analyses have been completed for the HYLIFE-II design using state-of-the-art codes. Work also continues on target fabrication and injection for HIF. A target injector experiment capable of >5 Hz operation has been designed and construction will start in 2002. Methods for mass-production of hohlraum targets are being evaluated with small-scale experiments and analyses. Progress in these areas will be reviewed

Constructing Potential Energy Surfaces for Polyatomic Systems: Recent Progress and New Problems

Directory of Open Access Journals (Sweden)

J. Espinosa-Garcia

2012-01-01

Full Text Available Different methods of constructing potential energy surfaces in polyatomic systems are reviewed, with the emphasis put on fitting, interpolation, and analytical (defined by functional forms approaches, based on quantum chemistry electronic structure calculations. The different approaches are reviewed first, followed by a comparison using the benchmark H + CH4 and the H + NH3 gas-phase hydrogen abstraction reactions. Different kinetics and dynamics properties are analyzed for these reactions and compared with the available experimental data, which permits one to estimate the advantages and disadvantages of each method. Finally, we analyze different problems with increasing difficulty in the potential energy construction: spin-orbit coupling, molecular size, and more complicated reactions with several maxima and minima, which test the soundness and general applicability of each method. We conclude that, although the field of small systems, typically atom-diatom, is mature, there still remains much work to be done in the field of polyatomic systems.

[Progress in microalgae culture system for biodiesel combined with reducing carbon dioxide emission].

Science.gov (United States)

Su, Hongyang; Zhou, Xuefei; Xia, Xuefen; Sun, Zhen; Zhang, Yalei

2011-09-01

Wastewater resources, CO2 emission reduction and microalgae biodiesel are considered as current frontier fields of energy and environmental researches. In this paper, we reviewed the progress in system of microalgae culture for biodiesel production by wastewater and stack gas. Multiple factors including microalgal species, nutrition, culture methods and photobioreactor, which were crucial to the cultivation of microalgae for biodiesel production, were discussed in detail. A valuable culture system of microalgae for biodiesel production or other high value products combined with the treatment of wastewater by microalgae was put forward through the optimizations of algal species and culture technology. The culture system coupled with the treatment of wastewater, the reduction of CO2 emission with the cultivation of microalgae for biodiesel production will reduce the production cost of microalgal biofuel production and the treatment cost of wastewater simultaneously. Therefore, it would be a promising technology with important environmental value, social value and economic value to combine the treatment of wastewater with the cultivation of microalgae for biodiesel production.

Biogas Opportunities Roadmap Progress Report

Energy Technology Data Exchange (ETDEWEB)

None, None

2015-12-01

In support of the Obama Administration's Climate Action Plan, the U.S. Department of Energy, the U.S. Environmental Protection Agency, and U.S. Department of Agriculture jointly released the Biogas Opportunities Roadmap Progress Report, updating the federal government's progress to reduce methane emissions through biogas systems since the Biogas Opportunities Roadmap was completed by the three agencies in July 2014. The report highlights actions taken, outlines challenges and opportunities, and identifies next steps to the growth of a robust biogas industry.

48 CFR 32.605 - Final decisions.

Science.gov (United States)

2010-10-01

... REQUIREMENTS CONTRACT FINANCING Contract Debts 32.605 Final decisions. (a) The contracting officer shall issue a final decision as required by 33.211 if— (1) The contracting officer and the contractor are unable... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Final decisions. 32.605...

Progress of the research and development on the geological disposal technology of HLW with aid of the industry/university collaboration system and fixed term researcher system

International Nuclear Information System (INIS)

Yamada, Fumitaka; Sonobe, Hitoshi; Igarashi, Hiroshi

2008-02-01

In Japan Atomic Energy Agency (JAEA), various systems associated with the collaboration with industries and universities on the Nuclear Fuel Cycle and the Postdoctoral Fellow system, etc. are enacted. These systems have been operated considering the needs of JAEA's program, industry and academia, resultantly contributed, for example, to basic research and the project development. The activities under these collaboration systems contain personal exchanges, the publication of the accomplishments and utilization of those, in research and development concerning geological disposal technology of high-level radioactive waste (HLW). These activities have progressed in Power Reactor and Nuclear Fuel Development Corporation (PNC) and Japan Nuclear Cycle Development Institute (JNC), which are the successive predecessors of JAEA, through JAEA. The accomplishments from these systems have been not only published as papers in journals and individual technical reports but also integrated into the project reports, accordingly contributed to the advancement of the national program on the geological disposal of HLW. In this report, the progress of the research and development under these systems was investigated from the beginning of the operation of the systems. The contribution to the research and development on geological disposal technology of HLW was also studied. On the basis of these studies, the future utilization of the systems of the collaboration was also discussed from the view point of the management of research and development program. A CD-ROM is attached as an appendix. (J.P.N.)

Rankine cycle generators using geothermal fluids. Final progress report

Energy Technology Data Exchange (ETDEWEB)

1981-01-01

The Rankine Cycle generator was delivered and installed at Gila Hot Springs. Trial runs were made at that time, using Freon 12 as the expansion fluid. These tests showed that the boiler capacity was inadequate. It could not extract enough heat to generate sufficient volumes of Freon gas at the heat and pressure necessary to operate the system at an acceptable level. Increasing and decreasing the flow of hot water had a direct influence on efficiency, but it was not a linear relationship. Added amounts of hot water increased the power very little, but raised the water temperature at the discharge point. This implied that the heat exchange capacity of the boiler was saturated. The reverse was found in the condenser system. There was little increase in pressure of the condenser when we switched from static to run mode. Efficiency was maintained even when the cold water flow was reduced as much as 40%. The tests using Freon 12 resulted in the conclusion that the boiler volume needs to be increased and/or the configuration changed to radically increase its efficiency.

Practical reliability and uncertainty quantification in complex systems : final report.

Energy Technology Data Exchange (ETDEWEB)

Grace, Matthew D.; Ringland, James T.; Marzouk, Youssef M. (Massachusetts Institute of Technology, Cambridge, MA); Boggs, Paul T.; Zurn, Rena M.; Diegert, Kathleen V. (Sandia National Laboratories, Albuquerque, NM); Pebay, Philippe Pierre; Red-Horse, John Robert (Sandia National Laboratories, Albuquerque, NM)

2009-09-01

The purpose of this project was to investigate the use of Bayesian methods for the estimation of the reliability of complex systems. The goals were to find methods for dealing with continuous data, rather than simple pass/fail data; to avoid assumptions of specific probability distributions, especially Gaussian, or normal, distributions; to compute not only an estimate of the reliability of the system, but also a measure of the confidence in that estimate; to develop procedures to address time-dependent or aging aspects in such systems, and to use these models and results to derive optimal testing strategies. The system is assumed to be a system of systems, i.e., a system with discrete components that are themselves systems. Furthermore, the system is 'engineered' in the sense that each node is designed to do something and that we have a mathematical description of that process. In the time-dependent case, the assumption is that we have a general, nonlinear, time-dependent function describing the process. The major results of the project are described in this report. In summary, we developed a sophisticated mathematical framework based on modern probability theory and Bayesian analysis. This framework encompasses all aspects of epistemic uncertainty and easily incorporates steady-state and time-dependent systems. Based on Markov chain, Monte Carlo methods, we devised a computational strategy for general probability density estimation in the steady-state case. This enabled us to compute a distribution of the reliability from which many questions, including confidence, could be addressed. We then extended this to the time domain and implemented procedures to estimate the reliability over time, including the use of the method to predict the reliability at a future time. Finally, we used certain aspects of Bayesian decision analysis to create a novel method for determining an optimal testing strategy, e.g., we can estimate the 'best' location to

Progression and prognosis in multiple system atrophy: an analysis of 230 Japanese patients.

Science.gov (United States)

Watanabe, Hirohisa; Saito, Yufuko; Terao, Shinichi; Ando, Tetsuo; Kachi, Teruhiko; Mukai, Eiichiro; Aiba, Ikuko; Abe, Yuji; Tamakoshi, Akiko; Doyu, Manabu; Hirayama, Masaaki; Sobue, Gen

2002-05-01

We investigated the disease progression and survival in 230 Japanese patients with multiple system atrophy (MSA; 131 men, 99 women; 208 probable MSA, 22 definite; mean age at onset, 55.4 years). Cerebellar dysfunction (multiple system atrophy-cerebellar; MSA-C) predominated in 155 patients, and parkinsonism (multiple system atrophy-parkinsonian; MSA-P) in 75. The median time from initial symptom to combined motor and autonomic dysfunction was 2 years (range 1-10). Median intervals from onset to aid-requiring walking, confinement to a wheelchair, a bedridden state and death were 3, 5, 8 and 9 years, respectively. Patients manifesting combined motor and autonomic involvement within 3 years of onset had a significantly increased risk of not only developing advanced disease stage but also shorter survival (P bedridden state, P bedridden state (P = 0.03) and death (P bedridden state and survival were no worse. Gender was not associated with differences in worsening of function or survival. On MRI, a hyperintense rim at the lateral edge of the dorsolateral putamen was seen in 34.5% of cases, and a 'hot cross bun' sign in the pontine basis (PB) in 63.3%. These putaminal and pontine abnormalities became more prominent as MSA-P and MSA-C features advanced. The atrophy of the cerebellar vermis and PB showed a significant correlation particularly with the interval following the appearance of cerebellar symptoms in MSA-C (r = 0.71, P r = 0.76 and P < 0.01, respectively), but the relationship between atrophy and functional status was highly variable among the individuals, suggesting that other factors influenced the functional deterioration. Atrophy of the corpus callosum was seen in a subpopulation of MSA, suggesting hemispheric involvement in a subgroup of MSA patients. The present study suggested that many factors are involved in the progression of MSA but, most importantly, the interval from initial symptom to combined motor and autonomic dysfunction can predict functional

Next Generation Risk Assessment: Incorporation of Recent Advances in Molecular, Computational, and Systems Biology (Final Report)

Science.gov (United States)

EPA announced the release of the final report, Next Generation Risk Assessment: Incorporation of Recent Advances in Molecular, Computational, and Systems Biology. This report describes new approaches that are faster, less resource intensive, and more robust that can help ...

Severity score system for progressive myelopathy: development and validation of a new clinical scale

Directory of Open Access Journals (Sweden)

R.M. Castilhos

2012-07-01

Full Text Available Progressive myelopathies can be secondary to inborn errors of metabolism (IEM such as mucopolysaccharidosis, mucolipidosis, and adrenomyeloneuropathy. The available scale, Japanese Orthopaedic Association (JOA score, was validated only for degenerative vertebral diseases. Our objective is to propose and validate a new scale addressing progressive myelopathies and to present validating data for JOA in these diseases. A new scale, Severity Score System for Progressive Myelopathy (SSPROM, covering motor disability, sphincter dysfunction, spasticity, and sensory losses. Inter- and intra-rater reliabilities were measured. External validation was tested by applying JOA, the Expanded Disability Status Scale (EDSS, the Barthel index, and the Osame Motor Disability Score. Thirty-eight patients, 17 with adrenomyeloneuropathy, 3 with mucopolysaccharidosis I, 3 with mucopolysaccharidosis IV, 2 with mucopolysaccharidosis VI, 2 with mucolipidosis, and 11 with human T-cell lymphotropic virus type-1 (HTLV-1-associated myelopathy participated in the study. The mean ± SD SSPROM and JOA scores were 74.6 ± 11.4 and 12.4 ± 2.3, respectively. Construct validity for SSPROM (JOA: r = 0.84, P < 0.0001; EDSS: r = -0.83, P < 0.0001; Barthel: r = 0.56, P < 0.002; Osame: r = -0.94, P < 0.0001 and reliability (intra-rater: r = 0.83, P < 0.0001; inter-rater: r = 0.94, P < 0.0001 were demonstrated. The metric properties of JOA were similar to those found in SSPROM. Several clinimetric requirements were met for both SSPROM and JOA scales. Since SSPROM has a wider range, it should be useful for follow-up studies on IEM myelopathies.

Adaptive pulse amplitude pulse width control of systems subject to Coulomb and viscous friction

NARCIS (Netherlands)

Wijdeven, van de J.J.M.; Singh, T.

2003-01-01

The focus of this paper is on adaptive controlof maneuvering rigid bodies in the presence offriction. The paper describes a simple techniquewhich include Pulse Amplitude and Pulse Widthmodulation to progressively move the system tothe desired final position. To account for uncertaintyin estimated

Drift compression and final focus systems for heavy ion inertial fusion

Energy Technology Data Exchange (ETDEWEB)

de Hoon, Michiel Jan Laurens [Univ. of California, Berkeley, CA (United States)

2001-01-01

Longitudinal compression of space-charge dominated beams can be achieved by imposing a head-to-tail velocity tilt on the beam. This tilt has to be carefully tailored, such that it is removed by the longitudinal space-charge repulsion by the time the beam reaches the end of the drift compression section. The transverse focusing lattice should be designed such that all parts of the beam stay approximately matched, while the beam smoothly expands transversely to the larger beam radius needed in the final focus system following drift compression. In this thesis, several drift compression systems were designed within these constraints, based on a given desired pulse shape at the end of drift compression systems were designed within these constraints, based on a given desired pulse shape at the end of drift compression. The occurrence of mismatches due to a rapidly increasing current was analyzed. In addition, the sensitivity of drift compression to errors in the initial velocity tilt and current profile was studied. These calculations were done using a new computer code that accurately calculates the longitudinal electric field in the space-charge dominated regime.

Response: Progress Takes Time.

Science.gov (United States)

Rist, Marilee C.

1984-01-01

Although declining enrollment and administrative seniority have hampered efforts to eliminate sex discrimination in employment practices in three Long Island, New York, school systems (Commack, Smithtown, and Bay Shore), progress is being made. Because of the Reagan administration's lack of support for affirmative action, however, litigation…

Battery‐Supercapacitor Hybrid Devices: Recent Progress and Future Prospects

Science.gov (United States)

Zuo, Wenhua; Li, Ruizhi; Zhou, Cheng; Xia, Jianlong

2017-01-01

Design and fabrication of electrochemical energy storage systems with both high energy and power densities as well as long cycling life is of great importance. As one of these systems, Battery‐supercapacitor hybrid device (BSH) is typically constructed with a high‐capacity battery‐type electrode and a high‐rate capacitive electrode, which has attracted enormous attention due to its potential applications in future electric vehicles, smart electric grids, and even miniaturized electronic/optoelectronic devices, etc. With proper design, BSH will provide unique advantages such as high performance, cheapness, safety, and environmental friendliness. This review first addresses the fundamental scientific principle, structure, and possible classification of BSHs, and then reviews the recent advances on various existing and emerging BSHs such as Li‐/Na‐ion BSHs, acidic/alkaline BSHs, BSH with redox electrolytes, and BSH with pseudocapacitive electrode, with the focus on materials and electrochemical performances. Furthermore, recent progresses in BSH devices with specific functionalities of flexibility and transparency, etc. will be highlighted. Finally, the future developing trends and directions as well as the challenges will also be discussed; especially, two conceptual BSHs with aqueous high voltage window and integrated 3D electrode/electrolyte architecture will be proposed. PMID:28725528

Power systems development facility. Quarterly technical progress report, January 1, 1994--March 31, 1994

Energy Technology Data Exchange (ETDEWEB)

1994-07-01

This quarterly technical progress report summarizes work completed during the last quarter of the Second Budget Period, January 1 through March 31, 1994, entitled {open_quotes}Hot Gas Cleanup Test Facility for Gasification and Pressurized Combustion.{close_quotes} The objective of this project is to evaluate hot gas particulate control technologies using coal-derived gas streams. This will entail the design, construction, installation, and use of a flexible test facility which can operate under realistic gasification and combustion conditions. The major particulate control device issues to be addressed include the integration of the particulate control devices into coal utilization systems, on-line cleaning techniques, chemical and thermal degradation of components, fatigue or structural failures, blinding, collection efficiency as a function of particle size, and scale-up of particulate control systems to commercial size.

Progressive outer retinal necrosis syndrome in the course of systemic lupus erythematosus.

Science.gov (United States)

Turno-Kręcicka, A; Tomczyk-Socha, M; Zimny, A

2016-12-01

Progressive outer retinal necrosis syndrome (PORN) is a severe clinical variant of necrotizing herpetic chorioretinitis, which occurs almost exclusively in patients with advanced acquired immunodeficiency syndrome (AIDS). To date, only a few cases of PORN have been reported in patients, mostly among those who were immunocompromised. To our knowledge, only one case of PORN in a patient with systemic lupus erythematosus (SLE) has been described. We report the case of a 44-year old HIV-negative patient with lupus nephritis, whom was being treated by mycophenolate mophetil (MMF), arechin and prednisone. After 14 months of MMF therapy, the patient revealed PORN symptoms; and several months later, the patient developed Type B primary central nervous system lymphoma (PCNSL). PORN is usually compared to acute retinal necrosis (ARN) syndrome, because of having the same causative agent: varicella zoster virus (VZV). There are also some similarities in clinical findings. Our observation supports the hypothesis that PORN symptoms in HIV-negative patients can be an intermediate form between ARN and PORN, and can vary according to the patient's immune status. © The Author(s) 2016.

Experimental and Theoretical Progress of Linear Collider Final Focus Design and ATF2 Facility

CERN Document Server

Seryi, Andrei; Zimmermann, Frank; Kubo, Kiyoshi; Kuroda, Shigeru; Okugi, Toshiyuki; Tauchi, Toshiaki; Terunuma, Nobuhiro; Urakawa, Junji; White, Glen; Woodley, Mark; Angal-Kalinin, Deepa

2014-01-01

In this brief overview we will reflect on the process of the design of the linear collider (LC) final focus (FF) optics, and will also describe the theoretical and experimental efforts on design and practical realisation of a prototype of the LC FF optics implemented in the ATF2 facility at KEK, Japan, presently being commissioned and operated.

Foundations for Improvements to Passive Detection Systems - Final Report

International Nuclear Information System (INIS)

Labov, S E; Pleasance, L; Sokkappa, P; Craig, W; Chapline, G; Frank, M; Gronberg, J; Jernigan, J G; Johnson, S; Kammeraad, J; Lange, D; Meyer, A; Nelson, K; Pohl, B; Wright, D; Wurtz, R

2004-01-01

This project explores the scientific foundation and approach for improving passive detection systems for plutonium and highly enriched uranium in real applications. Sources of gamma-ray radiation of interest were chosen to represent a range of national security threats, naturally occurring radioactive materials, industrial and medical radiation sources, and natural background radiation. The gamma-ray flux emerging from these sources, which include unclassified criticality experiment configurations as surrogates for nuclear weapons, were modeled in detail. The performance of several types of gamma-ray imaging systems using Compton scattering were modeled and compared. A mechanism was created to model the combine sources and background emissions and have the simulated radiation ''scene'' impinge on a model of a detector. These modeling tools are now being used in various projects to optimize detector performance and model detector sensitivity in complex measuring environments. This study also developed several automated algorithms for isotope identification from gamma-ray spectra and compared these to each other and to algorithms already in use. Verification testing indicates that these alternative isotope identification algorithms produced less false positive and false negative results than the ''GADRAS'' algorithms currently in use. In addition to these algorithms that used binned spectra, a new approach to isotope identification using ''event mode'' analysis was developed. Finally, a technique using muons to detect nuclear material was explored

Light particle emission measurements in heavy ion reactions: Progress report, June 1, 1988--May 31, 1989

International Nuclear Information System (INIS)

Petitt, G.A.

1989-01-01

We have completed another successful year of experimental work at the Heavy Ion Research Facility (HHIRF) and at Georgia State University (GSU). Since submitting our previous progress report we have completed our paper on neutron emission from products of the reaction 58 Ni + 165 Ho and it has been submitted to Physical Review C. Some of the details of these results are discussed below. We have installed the Vaxstation computer system for which we received supplemental funding from DOE during 1988-89 and it is being used to analyze the Ni + Ho data using the codes Pace and a modified version of Lilita, both of which we have been able to transfer to our Vaxstation systems from the Vax at ORNL with very minimal modification. The Exabyte tape drive which we ordered with the computer system was finally delivered at the end of January after months of delays. It is now being used to scan data tapes from our experiment to study neutron-neutron and neutron-charged-particle momentum correlations using the reaction 32 S + 197 Au at 25 MeV/nucleon. This data analysis can now proceed at a fast pace. Finally, we have continued our developmental work on the Hili detector system at ORNL, and have participated in experiments to study the predictions of the Dyabatic Dynamics model of particle emission using the Ni + Ni system and the HILI detector system

High energy experimental physics. Progress report and renewal proposal

International Nuclear Information System (INIS)

Rosen, J.; Miller, D.

1985-01-01

Technical progress is summarized for activities in these areas: study of charm particle production in hadronic collisions (data analysis); large-aperture multiparticle spectrometer; TEV I debuncher ring profile monitor; beta source monochromatizer; final reduction of data from pp and p anti p elastic scattering; high energy elastic scattering and cross section review; consequences of the Auberson-Kinoshita-Martin theorem for the nuclear slope parameter; planning and final design of the elastic scattering and total cross section experiment at the Tevatron Collider; a D-zero pp project and photoproduction experiment; lepton production in heavy-ion collisions; prompt gamma and massive lepton-pair production apparatus; and spin physics with the Fermilab polarized beam facility

The hypocretin/orexin system in sleep disorders: preclinical insights and clinical progress

Directory of Open Access Journals (Sweden)

Chow M

2016-03-01

Full Text Available Matthew Chow, Michelle CaoDepartment of Psychiatry and Behavioral Sciences, Division of Sleep Medicine, Stanford University School of Medicine, Stanford, CA, USAAbstract: Much of the understanding of the hypocretin/orexin (HCRT/OX system in sleep–wake regulation came from narcolepsy–cataplexy research. The neuropeptides hypocretin-1 and -2/orexin-A and -B (HCRT-1 and -2/OX-A and -B, respectively, as we know, are intimately involved in the regulation wakefulness. The HCRT/OX system regulates sleep–wake control through complex interactions between monoaminergic/cholinergic (wake-promoting and gamma-aminobutyric acid-ergic (sleep-promoting neuronal systems. Deficiency of HCRT/OX results in loss of sleep–wake control or stability with consequent unstable transitions between wakefulness to nonrapid eye movement and rapid eye movement sleep. This manifests clinically as abnormal daytime sleepiness with sleep attacks and cataplexy. Research on the development of HCRT/OX agonists and antagonists for the treatment of sleep disorders has dramatically increased with the US Food and Drug Administration approval of the first-in-class dual HCRT/OX receptor antagonist for the treatment of insomnia. This review focuses on the origin, mechanisms of HCRT/OX receptors, clinical progress, and applications for the treatment of sleep disorders.Keywords: hypocretin, orexin, narcolepsy, insomnia, orexin antagonist, orexin agonist

Metaheuristics progress as real problem solvers

CERN Document Server

Nonobe, Koji; Yagiura, Mutsunori

2005-01-01

Metaheuristics: Progress as Real Problem Solvers is a peer-reviewed volume of eighteen current, cutting-edge papers by leading researchers in the field. Included are an invited paper by F. Glover and G. Kochenberger, which discusses the concept of Metaheuristic agent processes, and a tutorial paper by M.G.C. Resende and C.C. Ribeiro discussing GRASP with path-relinking. Other papers discuss problem-solving approaches to timetabling, automated planograms, elevators, space allocation, shift design, cutting stock, flexible shop scheduling, colorectal cancer and cartography. A final group of methodology papers clarify various aspects of Metaheuristics from the computational view point.

Improving the Efficient of Ernie Turner Center. Final Progress Report

Energy Technology Data Exchange (ETDEWEB)

Fredeen, Amy

2011-03-21

The objective of this project was to complete the specifications and drawings for a variable speed kitchen exhaust system and the boiler heating system which when implemented will improve the heating efficiency of the building. The design work was focused in two key areas: kitchen ventilation and heating for the Ernie Turner Center building (ETC). RSA completed design work and issued a set of 100% drawings. RSA also worked with a cost estimator to put together a detailed cost estimate for the project. The design components are summarized.

Decontamination Systems Information and Research Program. Quarterly technical progress report, January 1--March 31, 1993

Energy Technology Data Exchange (ETDEWEB)

1993-04-01

This reports reports the progress/efforts performed on six technical projects: 1. systematic assessment of the state of hazardous waste clean-up technologies; 2. site remediation technologies (SRT):drain- enhanced soil flushing for organic contaminants removal; 3. SRT: in situ bio-remediation of organic contaminants; 4. excavation systems for hazardous waste sites: dust control methods for in-situ nuclear waste handling; 5. chemical destruction of polychlorinated biphenyls; and 6. development of organic sensors: monolayer and multilayer self-assembled films for chemical sensors.

Discovering biological progression underlying microarray samples.

Directory of Open Access Journals (Sweden)

Peng Qiu

2011-04-01

Full Text Available In biological systems that undergo processes such as differentiation, a clear concept of progression exists. We present a novel computational approach, called Sample Progression Discovery (SPD, to discover patterns of biological progression underlying microarray gene expression data. SPD assumes that individual samples of a microarray dataset are related by an unknown biological process (i.e., differentiation, development, cell cycle, disease progression, and that each sample represents one unknown point along the progression of that process. SPD aims to organize the samples in a manner that reveals the underlying progression and to simultaneously identify subsets of genes that are responsible for that progression. We demonstrate the performance of SPD on a variety of microarray datasets that were generated by sampling a biological process at different points along its progression, without providing SPD any information of the underlying process. When applied to a cell cycle time series microarray dataset, SPD was not provided any prior knowledge of samples' time order or of which genes are cell-cycle regulated, yet SPD recovered the correct time order and identified many genes that have been associated with the cell cycle. When applied to B-cell differentiation data, SPD recovered the correct order of stages of normal B-cell differentiation and the linkage between preB-ALL tumor cells with their cell origin preB. When applied to mouse embryonic stem cell differentiation data, SPD uncovered a landscape of ESC differentiation into various lineages and genes that represent both generic and lineage specific processes. When applied to a prostate cancer microarray dataset, SPD identified gene modules that reflect a progression consistent with disease stages. SPD may be best viewed as a novel tool for synthesizing biological hypotheses because it provides a likely biological progression underlying a microarray dataset and, perhaps more importantly, the

Status of system 80+ design certification

International Nuclear Information System (INIS)

Matzie, R.A.

1992-01-01

This paper reports that 1991 was a year of great progress in the design certification process for ABB Combustion Engineering Nuclear Power's 1300 MWe evolutionary advanced light water reactor (ALWR) plant, System 80+. As the next generation of nuclear power plants move toward final design approval by the U.S. Nuclear Regulatory Commission (NRC), elements of the design process that emphasize operation and maintenance have become the focus. For System 80+, licensing under the new design certification process is now concentrated on operational support, human engineering, plant layout, and computer-aided engineering

Laser Fusion Program at LASL. Progress report, July 1--December 31, 1977

International Nuclear Information System (INIS)

Skoberne, F.

1978-12-01

Progress in the development of high-energy short-pulse CO 2 laser systems for fusion research is reported. Among the achievements discussed are an increase in on-target energy of the Two-Beam System to 375 J per beam; operation of one Eight-Beam System module at the design point of 1.2 kJ at a power of > 2 TW; and the on-schedule development of our 100- to 200-TW laser Antares. Target designs based on the LASNEX code incorporating new theoretical insights are described, culminating in a double-shell exploding-pusher target that attains a high degree of symmetry through hot-electron transport in an exploding outer shell. Studies of laser light absorption are outlined, which confirmed that the values for CO 2 are nearly identical to those obtained with Nd:glass lasers. Unique diagnostics are described, which allow one to measure properties of x-ray emission not previously accessible, and which provide absorption data of sufficient accuracy for direct comparison with theory. Finally, various feasibility and systems studies are summarized, such as the successful modeling of short-pulse amplification in large three-pass CO 2 laser amplifiers, as verified experimentally

Laser Fusion Program at LASL. Progress report, July 1--December 31, 1977

Energy Technology Data Exchange (ETDEWEB)

Skoberne, F. (comp.)

1978-12-01

Progress in the development of high-energy short-pulse CO/sub 2/ laser systems for fusion research is reported. Among the achievements discussed are an increase in on-target energy of the Two-Beam System to 375 J per beam; operation of one Eight-Beam System module at the design point of 1.2 kJ at a power of > 2 TW; and the on-schedule development of our 100- to 200-TW laser Antares. Target designs based on the LASNEX code incorporating new theoretical insights are described, culminating in a double-shell exploding-pusher target that attains a high degree of symmetry through hot-electron transport in an exploding outer shell. Studies of laser light absorption are outlined, which confirmed that the values for CO/sub 2/ are nearly identical to those obtained with Nd:glass lasers. Unique diagnostics are described, which allow one to measure properties of x-ray emission not previously accessible, and which provide absorption data of sufficient accuracy for direct comparison with theory. Finally, various feasibility and systems studies are summarized, such as the successful modeling of short-pulse amplification in large three-pass CO/sub 2/ laser amplifiers, as verified experimentally.

Recent progress in sensor-enhanced health information systems - slowly but sustainably.

Science.gov (United States)

Marschollek, Michael

2009-12-01

The use of health-enabling technologies is regarded as one important means to face some of the challenges which accompany the demographic change with an expected rise in multi-morbidity and an increased need of care. A precondition for the sensible use of these technologies is their integration in existing information system structures, and - preferably - the enhancement of these into sensor-enhanced health information systems (seHIS). The aim of this review is to report on recent progress in seHIS, and thus to identify relevant areas of research that have to be addressed to provide patient-centered services in a semantically interoperable environment. A literature search in PubMed/Medline was combined with a manual search of papers (n = 1004) in three prominent health/medical informatics journals and one biomedical engineering journal starting from the year 2007. Despite a multitude of papers that present advanced systems using health-enabling technologies, only few papers could be identified that explicitly describe the design of seHIS or the integration of health-enabling technologies into health information systems. Recurring statements emphasise the importance of the following areas of research: patient-centered care using all available sources of information, data security, the stringent use of data representation and device connectivity standards, and adequate methods for data fusion and diagnostic analysis. There is a broad range of research in health-enabling technologies, often focused on specific diseases. The transition from current institution-centered health information systems to person-centered seHIS will be gradual, yet unavoidable for tapping the full potential of health-enabling technologies. seHIS is a growing field of research, and many ambitious challenges are still open. This literature review gives a brief outline of the most frequently mentioned research foci.

Progression og innovation – hvordan kan de to begreber berige hinanden og universitetsundervisning?

DEFF Research Database (Denmark)

Jensen, Tine Lynfort

2014-01-01

berige hinanden på universiteterne generelt. In the article, the concepts of innovation and progression are linked to one another based on the author’s experiences with teaching innovation to humanistic students. In particular, there is a focus on competency assessment as a foundation...... bidrager til progressionen i undervisningsforløb. Der præsenteres en udviklet model med afsæt i denne form for undervisning, hvor progressionsbegrebet søges forstået og forklaret på tre niveauer. Slutteligt diskuteres, hvorledes innovation og progression som begreber og som undervisningsaktiviteter kan...... for this interrelation as the student’s awareness of their own resources contributes to progression in courses of study. A newly developed model is presented in the article. The concept of progression is understood and explained in the context of innovation teaching at three levels. Finally, it is discussed how...

What is the Integral in Integral Education? From Progressive Pedagogy to Integral Pedagogy

Directory of Open Access Journals (Sweden)

Tom Murray

2009-06-01

Full Text Available Integrally-informed educational approaches have much in common withprogressive (including reform, alternative, holistic, and transformative approaches, andshare many of the same values. One function of the integral approach is to provide anoverarching model within which to coordinate different progressive methods. Thoughintegral adds much more than that, descriptions of integral education sometimes soundlike progressive educational principles recast with new terminology. This essay attemptsto clarify what the integral approach adds over and above progressive educationaltheories. After an overview of progressive pedagogical principles, the integral approachis discussed in terms of integral as a model, a method, a community, and a developmentalstage. Integral as a type of consciousness or developmental level is elaborated upon asconsisting of construct-awareness, ego-awareness, relational-awareness, and systemawareness,all important to the educational process. Finally, challenges and supportsystems for realizing integral education are discussed.

Does More Progressive Tax Make Tax Discipline Weaker?

OpenAIRE

Tatiana Damjanovic

2005-01-01

This paper investigates the relationship between the disparity in tax base and tax collection. I address the tax collection problem with traditional industrial organization approach. Thus, I model the "tax minimization" industry where the supplier helps taxpayers to avoid their tax liability. I find that lower income inequality as well as a less progressive tax code may result in a smaller number of tax payers committing to their tax duties. Finally, I question the reduction in the highest ta...

Climate Reanalysis: Progress and Future Prospects

Science.gov (United States)

Gelaro, Ron

2018-01-01

Reanalysis is the process whereby an unchanging data assimilation system is used to provide a consistent reprocessing of observations, typically spanning an extended segment of the historical data record. The process relies on an underlying model to combine often-disparate observations in a physically consistent manner, enabling production of gridded data sets for a broad range of applications including the study of historical weather events, preparation of climatologies, business sector development and, more recently, climate monitoring. Over the last few decades, several generations of reanalyses of the global atmosphere have been produced by various operational and research centers, focusing more or less on the period of regular conventional and satellite observations beginning in the mid to late twentieth century. There have also been successful efforts to extend atmospheric reanalyses back to the late nineteenth and early twentieth centuries, using mostly surface observations. Much progress has resulted from (and contributed to) advancements in numerical weather prediction, especially improved models and data assimilation techniques, increased computing capacity, the availability of new observation types and efforts to recover and improve the quality of historical ones. The recent extension of forecast systems that allow integrated modeling of meteorological, oceanic, land surface, and chemical variables provide the basic elements for coupled data assimilation. This has opened the door to the development of a new generation of coupled reanalyses of the Earth system, or integrated Earth system analyses (IESA). Evidence so far suggests that this approach can improve the analysis of currently uncoupled components of the Earth system, especially at their interface, and lead to increased predictability. However, extensive analysis coupling as envisioned for IESA, while progressing, still presents significant challenges. These include model biases that can be

MINIMARS conceptual design: Final report

International Nuclear Information System (INIS)

Lee, J.D.

1986-09-01

This volume contains the following sections: (1) fueling systems; (2) blanket; (3) alternative blanket concepts; (4) halo scraper/direct converter system study and final conceptual design; (5) heat-transport and power-conversion systems; (6) tritium systems; (7) minimars air detritiation system; (8) appropriate radiological safety design criteria; and (9) cost estimate

Tumour model with intrusive morphology, progressive phenotypical heterogeneity and memory

Science.gov (United States)

Atangana, Abdon; Alqahtani, Rubayyi T.

2018-03-01

The model of a tumour, taking into account invasive morphology, progressive phenotypical heterogeneity and also memory, is developed and analyzed in this paper. Three models are investigated: first we consider the model describing the proliferation concentrates in proximity of tumour boundaries, in which the oxygen levels are pronounced. Then we consider the model where the oxygen around the tumour is considered to be unchanged by the vascular system. Finally, we investigate the model of growth of tumours using the concept of non-local operators with the Mittag-Leffler kernel. We provide the numerical solution using the extended 3/8 Simpson method for the new trends of fractional integration for the proliferation concentrates in the proximity of the tumour model. Then we provide the exact solutions of the Gompertz model with three different fractional differentiations involving power law, exponential decay law and the Mittag-Leffler law.

Progress in Development of an Airborne Turbulence Detection System

Science.gov (United States)

Hamilton, David W.; Proctor, Fred H.

2006-01-01

Aircraft encounters with turbulence are the leading cause of in-flight injuries (Tyrvanas 2003) and have occasionally resulted in passenger and crew fatalities. Most of these injuries are caused by sudden and unexpected encounters with severe turbulence in and around convective activity (Kaplan et al 2005). To alleviate this problem, the Turbulence Prediction and Warning Systems (TPAWS) element of NASA s Aviation Safety program has investigated technologies to detect and warn of hazardous in-flight turbulence. This effort has required the numerical modeling of atmospheric convection: 1) for characterizing convectively induced turbulence (CIT) environments, 2) for defining turbulence hazard metrics, and 3) as a means of providing realistic three-dimensional data sets that can be used to test and evaluate turbulence detection sensors. The data sets are being made available to industry and the FAA for certification of future airborne turbulence-detection systems (ATDS) with warning capability. Early in the TPAWS project, a radar-based ATDS was installed and flight tested on NASA s research aircraft, a B-757. This ATDS utilized new algorithms and hazard metrics that were developed for use with existing airborne predictive windshear radars, thus avoiding the installation of new hardware. This system was designed to detect and warn of hazardous CIT even in regions with weak radar reflectivity (i.e. 5-15 dBz). Results from an initial flight test of the ATDS were discussed in Hamilton and Proctor (2002a; 2002b). In companion papers (Proctor et al 2002a; 2002b), a numerical simulation of the most significant encounter from that flight test was presented. Since the presentation of these papers a second flight test has been conducted providing additional cases for examination. In this paper, we will present results from NASA s flight test and a numerical model simulation of a turbulence environment encountered on 30 April 2002. Progress leading towards FAA certification of

Commercial LFCM vitrification technology. Quarterly progress report, October-December 1984

Energy Technology Data Exchange (ETDEWEB)

Burkholder, H.C.; Jarrett, J.H. (comps.)

1985-07-01

This report is the first in a series of quarterly reports compiled by the Nuclear Waste Treatment Program Office at Pacific Northwest Laboratory to document progress on commercial liquid-fed ceramic melter (LFCM) vitrification technology. Progress in the following technical subject areas during the first quarter of FY 1985 is discussed: pretreatment systems, melting process chemistry, glass development and characterization, feed preparation and transfer systems, melter systems, canister filling and handling systems, off-gas systems, process/product modeling and control, and supporting studies. 33 figs., 12 tabs.

Principles for system level electrochemistry

Science.gov (United States)

Thaller, L. H.

1986-01-01

The higher power and higher voltage levels anticipated for future space missions have required a careful review of the techniques currently in use to preclude battery problems that are related to the dispersion characteristics of the individual cells. Not only are the out-of-balance problems accentuated in these larger systems, but the thermal management considerations also require a greater degree of accurate design. Newer concepts which employ active cooling techniques are being developed which permit higher rates of discharge and tighter packing densities for the electrochemical components. This paper will put forward six semi-independent principles relating to battery systems. These principles will progressively address cell, battery and finally system related aspects of large electrochemical storage systems.

A final focus system for the Next Linear Collider

International Nuclear Information System (INIS)

Zimmermann, F.; Brown, K.; Emma, P.; Helm, R.; Irwin, J.; Tenenbaum, P.; Wilson, P.

1995-06-01

The final focus of the Next Linear Collider (NLC) demagnifies electron and positron beams of 250--750 GeV energy down to a transverse size of about 2.5 x 350 nm 2 at the interaction point (IP). The basic layout, momentum bandwidth, vibration tolerances, wakefield effects, and the tunability of the proposed final focus design are discussed. Also a perspective is given on the crab cavity and on effects of the solenoid field in the interaction region

Columbia River System Operation Review final environmental impact statement. Appendix T: Comments and responses

International Nuclear Information System (INIS)

1995-11-01

The System Operation Review (SOR) is a study and environmental compliance process being used by the three Federal agencies to analyze future operations of the system and river use issues. The goal of the SOR is to achieve a coordinated system operation strategy for the river that better meets the needs of all river users. This technical appendix addresses only the effects of alternative system operating strategies for managing the Columbia River system. This appendix documents the public and agency review of the SOR Draft EIS and how the SOR agencies used the review to formulate the FINAL EIS. The appendix includes a summary of the review process, a discussion of the nature of the comments, a list of all commentors, reproductions of comment letters, and responses to all comments. Changes in the EIS text in response to comments are noted in the responses

Systems study 'Alternative Entsorgung'. Final report. Technical annex 10

International Nuclear Information System (INIS)

Hartje, B.; Kronschnabel, H.; Mueller, W.F.W.

1984-01-01

There is an investigation whether accessibility can be produced to fuel elements stored in a salt mine. All solutions of the problem were followed up until the technically best one was found. Two conditions must be fulfilled for access to the final storage barrel: - There must be a climate which is suitable for people. The Mining Order is the basis for this. - The pit building must be fixed, in the convergence in the salt mine should not lead to it becoming impossible to reach part of the mine. Due to heat-producing waste, rock temperatures are caused in the salt mine, in which mining is no longer possible. Building on the idea of cooling the whole final storage area using concentric sections, the amount of heat to be removal was first estimated. Cooling of the whole final storage area proved to be technically unjustifiable and uninteresting at present. (orig./HP) [de

Electron-beam-fusion progress report, January--June 1976

International Nuclear Information System (INIS)

1976-10-01

Research progress is reported for the following areas: (1) Proto I, (2) Proto II, (3) EBFA, (4) power flow, (5) contract progress reports, (6) progress in the Sandia program, (7) repetitively operated pulse generator development, (8) electron beam power from inductive storage, (9) fusion target design, (10) beam physics research, (11) power flow, (12) heavy ion fusion, (13) particle beam source development, (14) beam target interaction and target response studies, (15) diagnostic development, and (16) hybrid systems

Recovery of valuable chlorosilane intermediates by a novel waste conversion process. Technical report for phase IIIA (final) and phase IIIB (progress)

Energy Technology Data Exchange (ETDEWEB)

Anderson, K.E.

1998-10-01

From July 1994 through May 1998, direct process residue (DPR) hydrogenolysis has been studied in the laboratory, at a small Pilot Plant, and finally at a larger Pilot Plant within Dow Corning`s Carrollton, Kentucky plant. The system reacts filtered DPR with monomer at high temperature and pressure. The process demonstrates DPR conversion up to 86%. The reaction product contains high concentrations of valuable monomers such as dimethyldichlorosilane and methyldichlorosilane. A larger DPR hydrogenolysis reactor based on these results is being designed for operation in Europe at Dow Corning`s Barry, Wales site.

The final checkpoint. Cancer as an adaptive evolutionary mechanism

Directory of Open Access Journals (Sweden)

Rumena Petkova

2016-05-01

Full Text Available The mechanisms for identification of DNA damage and repair usually manage DNA damage very efficiently. If damaged cells manage to bypass the checkpoints where the integrity of the genome is assessed and the decisions whether to proceed with the cell cycle are made, they may evade the imperative to stop dividing and to die. As a result, cancer may develop. Warding off the potential sequence-altering effects of DNA damage during the life of the individual or the existence span of the species is controlled by a set of larger checkpoints acting on a progressively increasing scale, from systematic removal of damaged cells from the proliferative pool by means of repair of DNA damage/programmed cell death through ageing to, finally, cancer. They serve different purposes and act at different levels of the life cycle, safeguarding the integrity of the genetic backup of the individual, the genetic diversity of the population, and, finally, the survival of the species and of life on Earth. In the light of the theory that cancer is the final checkpoint or the nature's manner to prevent complex organisms from living forever at the expense of genetic stagnation, the eventual failure of modern anti-cancer treatments is only to be expected. Nevertheless, the medicine of today and the near future has enough potential to slow down the progression to terminal cancer so that the life expectancy and the quality of life of cancer-affected individuals may be comparable to those of healthy aged individuals.

Final focus nomenclature

International Nuclear Information System (INIS)

Erickson, R.

1986-01-01

The formal names and common names for all devices in the final focus system of the SLC are listed. The formal names consist of a device type designator, microprocessor designator, and a four-digit unit number

Idea Bank: Progress through Incentives: How One Music Program Helps Students Progress to Higher Levels of Musicianship

Science.gov (United States)

Boyd, Joshua

2013-01-01

Students are motivated when they have a constant system of rewards. They have a desire to please others and be recognized. It was with this idea in mind that the Smokey Road Middle School Band in Newman, Georgia, started using the "Power in the Progress System" in 2011. This system, created by H. Dwight Satterwhite, a professor of music…

Progressive multiple sclerosis: from pathogenic mechanisms to treatment.

Science.gov (United States)

Correale, Jorge; Gaitán, María I; Ysrraelit, María C; Fiol, Marcela P

2017-03-01

During the past decades, better understanding of relapsing-remitting multiple sclerosis disease mechanisms have led to the development of several disease-modifying therapies, reducing relapse rates and severity, through immune system modulation or suppression. In contrast, current therapeutic options for progressive multiple sclerosis remain comparatively disappointing and challenging. One possible explanation is a lack of understanding of pathogenic mechanisms driving progressive multiple sclerosis. Furthermore, diagnosis is usually retrospective, based on history of gradual neurological worsening with or without occasional relapses, minor remissions or plateaus. In addition, imaging methods as well as biomarkers are not well established. Magnetic resonance imaging studies in progressive multiple sclerosis show decreased blood-brain barrier permeability, probably reflecting compartmentalization of inflammation behind a relatively intact blood-brain barrier. Interestingly, a spectrum of inflammatory cell types infiltrates the leptomeninges during subpial cortical demyelination. Indeed, recent magnetic resonance imaging studies show leptomeningeal contrast enhancement in subjects with progressive multiple sclerosis, possibly representing an in vivo marker of inflammation associated to subpial demyelination. Treatments for progressive disease depend on underlying mechanisms causing central nervous system damage. Immunity sheltered behind an intact blood-brain barrier, energy failure, and membrane channel dysfunction may be key processes in progressive disease. Interfering with these mechanisms may provide neuroprotection and prevent disability progression, while potentially restoring activity and conduction along damaged axons by repairing myelin. Although most previous clinical trials in progressive multiple sclerosis have yielded disappointing results, important lessons have been learnt, improving the design of novel ones. This review discusses mechanisms involved

Decontamination Systems Information and Research Program. Quarterly technical progress report, January 1--March 31, 1994

Energy Technology Data Exchange (ETDEWEB)

1994-05-01

West Virginia University (WVU) and the US DOE Morgantown Energy Technology Center (METC) entered into a Cooperative Agreement on August 29, 1992 entitled ``Decontamination Systems Information and Research Programs.`` Stipulated within the Agreement is the requirement that WVU submit to METC a series of Technical Progress Reports on a quarterly basis. This report comprises the first Quarterly Technical Progress Report for Year 2 of the Agreement. This report reflects the progress and/or efforts performed on the sixteen (16) technical projects encompassed by the Year 2 Agreement for the period of January 1 through March 31, 1994. In situ bioremediation of chlorinated organic solvents; Microbial enrichment for enhancing in-situ biodegradation of hazardous organic wastes; Treatment of volatile organic compounds (VOCs) using biofilters; Drain-enhanced soil flushing (DESF) for organic contaminants removal; Chemical destruction of chlorinated organic compounds; Remediation of hazardous sites with steam reforming; Soil decontamination with a packed flotation column; Use of granular activated carbon columns for the simultaneous removal of organics, heavy metals, and radionuclides; Monolayer and multilayer self-assembled polyion films for gas-phase chemical sensors; Compact mercuric iodide detector technology development; Evaluation of IR and mass spectrometric techniques for on-site monitoring of volatile organic compounds; A systematic database of the state of hazardous waste clean-up technologies; Dust control methods for insitu nuclear and hazardous waste handling; Winfield Lock and Dam remediation; and Socio-economic assessment of alternative environmental restoration technologies.

Progression of trunk imbalance in adolescent idiopathic scoliosis with a thoracolumbar/lumbar curve: is it predictable at the initial visit?

Science.gov (United States)

Hwang, Chang Ju; Lee, Choon Sung; Lee, Dong-Ho; Cho, Jae Hwan

2017-11-01

OBJECTIVE Progression of trunk imbalance is an important finding during follow-up of patients with adolescent idiopathic scoliosis (AIS). Nevertheless, no factors that predict progression of trunk imbalance have been identified. The purpose of this study was to identify parameters that predict progression of trunk imbalance in cases of AIS with a structural thoracolumbar/lumbar (TL/L) curve. METHODS This study included 105 patients with AIS and a structural TL/L curve who were followed up at an outpatient clinic. Patients with trunk imbalance (trunk shift ≥ 20 mm) at the initial visit were excluded. All patients were followed up for more than 2 years. Patients were divided into the following groups according to progression of trunk imbalance: 1) Group P, trunk shift ≥ 20 mm at the final visit and degree of progression ≥ 10 mm; and 2) Group NP, trunk shift imbalance with progression ≥ 10 mm at the final visit (Group P). Multivariate logistic regression analysis identified a lower Risser grade (p = 0.002) and a greater initial AVR (p = 0.020) as predictors of progressive trunk imbalance. A change in LEV tilt during follow-up was associated with trunk imbalance (p = 0.001). CONCLUSIONS Risser grade and AVR measured at the initial visit may predict progression of trunk imbalance. Surgeons should consider the risk of progressive trunk imbalance if patients show skeletal immaturity and a greater AVR at the initial visit.

Sulfur dioxide allowances. Trading and technological progress

International Nuclear Information System (INIS)

Kumar, Surender; Managi, Shunsuke

2010-01-01

The US Clean Air Act Amendments introduce an emissions trading system to regulate SO 2 emissions. This study finds that changes in SO 2 emissions prices are related to innovations induced by these amendments. We find that electricity-generating plants are able to increase electricity output and reduce emissions of SO 2 and NO x from 1995 to 2007 due to the introduction of the allowance trading system. However, compared to the approximate 8% per year of exogenous technological progress, the induced effect is relatively small, and the contribution of the induced effect to overall technological progress is about 1-2%. (author)

Final focus nomenclature

Energy Technology Data Exchange (ETDEWEB)

Erickson, R.

1986-08-08

The formal names and common names for all devices in the final focus system of the SLC are listed. The formal names consist of a device type designator, microprocessor designator, and a four-digit unit number. (LEW)

Progress Report on the Construction of SOLEIL

CERN Document Server

Level, Marie Paule; Brunelle, Pascale; Chaput, Roger; Dael, Antoine; Denard, Jean-Claude; Filhol, Jean-Marc; Godefroy, Jean-Marie; Herbeaux, Christian; Le Roux, V; Marchand, Patrick; Nadji, Amor; Nadolski, Laurent S; Nagaoka, Ryutaro; Tordeux, M A

2005-01-01

This paper reports the progress achieved in the construction of the accelerators of SOLEIL. Started in January 2002, the construction comes near to its end and the installation of the equipment on the site has begun from September 2004 and shall be completed within one year. The progress on the LINAC and Booster are reported separately, therefore this paper will focus more particularly on the Storage Ring: Dedicated measuring benches have been built to perform the magnetic measurements on all the magnets and the results of measurements have been analysed in term of particle dynamics behaviour in order to prepare the operating point for the commissioning. The status of innovative developments engaged from the beginning as super-conducting RF cavities, NEG coated vacuum chambers and BPMs digital electronics will be described. The construction of the first 6 insertion devices is also well advanced and will be reported. Finally, the machine impedance budget was further evaluated with consequently, still some modi...

Markers, Cofactors and Staging Systems in the Study of HIV Disease Progression: A Review

Directory of Open Access Journals (Sweden)

MC Portela

1997-07-01

Full Text Available This paper is aimed at providing a comprehensive review of markers, cofactors and staging systems used for HIV disease, focusing on some aspects that nowadays could even be considered historical, and advancing in current issues such as the prognostic value of viral load measurements, viral genotypic and phenotypic characterization, and new HIV disease treatment protocols. CD4+ cell values, combined with the new viral markers mentioned are promising as a parsimonious predictor set for defining both severity and progression. An adequate predictor of patient resource use for planning purposes still needs to be defined

Emerging drugs for primary progressive multiple sclerosis.

Science.gov (United States)

Narayan, Ram Narendra; Forsthuber, Thomas; Stüve, Olaf

2018-04-24

The identification of effective therapies for progressive forms of multiple sclerosis (MS) has remains a priority and challenge for the global MS community. Despite a few proposed mechanisms, a more complete understanding of the mechanisms involved in the pathogenesis of these MS phenotypes, animal models that incorporate these pathogenic characteristics, novel trial designs, drug repurposing strategies, and new models of collaboration between clinical and basic science personnel may be required in identifying effective therapies. Areas covered: Here, we review the current knowledge on putative pathogenic mechanisms in primary progressive MS (PPMS). Also, the rationale and outcomes of key phase II or III trial initiatives in PPMS are summarized. Future perspectives are outlined. Expert opinion: The recent approval of ocrelizumab is a major milestone forward in the therapy of PPMS. One reason for success of this drug is appropriate patient selection. The ultimate goal in PPMS therapy should be the reversal of disability, and the arrest of disease progression. Our current understanding of PPMS suggests that a combination of immune-modulatory, myelin-restorative, and neuro-regenerative therapies particularly early in the disease course would be a reasonable strategy. Finally, selection of appropriate patients, selection of appropriate outcomes and monitoring therapy is again crucial for success of therapeutic strategies.