First-year Engineering Education with the Creative Electrical Engineering Laboratory

Science.gov (United States)

Tsukamoto, Takehiko; Sugito, Tetsumasa; Ozeki, Osamu; Ushiroda, Sumio

The Department of Electrical and Electronic Engineering in Toyota National College of Technology has put great emphasis on fundamental subjects. We introduced the creative electrical engineering laboratory into the first-year engineering education since 1998. The laboratory concentrates on the practice exercise. The final questionnaire of students showed that our first-year education is very effective to promote students motivation and their scholastic ability in engineering.

Results of Waste Transfer and Back-Dilution in Tanks 241-SY-101 and 241-SY-102

International Nuclear Information System (INIS)

Mahoney, L.A.; Antoniak, Z.I.; Barton, W.B.; Conner, J.M.; Kirch, N.W.; Stewart, C.W.; Wells, B.E.

2000-01-01

This report chronicles the process of remediation of the flammable gas hazard in Tank 241-SY-101 (SY-101) by waste transfer and back-dilution from December 18, 1999 through April 2, 2000. A brief history is given of the development of the flammable gas retention and release hazard in this tank, and the transfer and dilution systems are outlined. A detailed narrative of each of the three transfer and dilution campaigns is given to provide structure for the balance of the report. Details of the behavior of specific data are then described, including the effect of transfer and dilution on the waste levels in Tanks SY-101 and SY-102, data from strain gauges on equipment suspended from the tank dome, changes in waste configuration as inferred from neutron and gamma logs, headspace gas concentrations, waste temperatures, and the mixerpump operating performance. Operating data and performance of the transfer pump in SY-101 are also discussed

Hazard evaluation for transfer of waste from tank 241-SY-101 to tank 241-SY-102

International Nuclear Information System (INIS)

SHULTZ, M.V.

1999-01-01

Tank 241-SY-101 (SY-101) waste level growth is an emergent, high priority issue. The purpose of this document is to record the hazards evaluation process and document potential hazardous conditions that could lead to the release of radiological and toxicological material from the proposed transfer of a limited quantity (approximately 100,000 gallons) of waste from SY-101 to 241-SY-102 (SY-102). The results of the hazards evaluation will be compared to the current Tank Waste Remediation System (TWRS) Basis for Interim Operation (HNF-SD-WM-BIO-001, 1998, Revision 1) to identify any hazardous conditions where Authorization Basis (AB) controls may not be sufficient or may not exist. Comparison to LA-UR-92-3196, A Safety Assessment for Proposed Pump Mixing Operations to Mitigate Episodic Gas Releases in Tank 241-SY-101, was also made in the case of transfer pump removal activities. This document is not intended to authorize the activity or determine the adequacy of controls; it is only intended to provide information about the hazardous conditions associated with this activity. The Unreviewed Safety Question (USQ) process will be used to determine the adequacy of controls and whether the proposed activity is within the AB. This hazard evaluation does not constitute an accident analysis

Pragmatic electrical engineering systems and instruments

CERN Document Server

Eccles, William

2011-01-01

Pragmatic Electrical Engineering: Systems and Instruments is about some of the non-energy parts of electrical systems, the parts that control things and measure physical parameters. The primary topics are control systems and their characterization, instrumentation, signals, and electromagnetic compatibility. This text features a large number of completely worked examples to aid the reader in understanding how the various principles fit together.While electric engineers may find this material useful as a review, engineers in other fields can use this short lecture text as a modest introduction

Electrical engineering a pocket reference

CERN Document Server

Schmidt-Walter, Heinz

2007-01-01

This essential reference offers you a well-organized resource for accessing the basic electrical engineering knowledge you need for your work. Whether you're an experienced engineer who appreciates an occasional refresher in key areas, or a student preparing to enter the field, Electrical Engineering: A Pocket Reference provides quick and easy access to fundamental principles and their applications. You also find an extensive collection of time-saving equations that help simplify your daily projects.Supported with more than 500 diagrams and figures, 60 tables, and an extensive index, this uniq

Electrical engineer's reference book

CERN Document Server

Jones, G R

2013-01-01

A long established reference book: radical revision for the fifteenth edition includes complete rearrangement to take in chapters on new topics and regroup the subjects covered for easy access to information.The Electrical Engineer's Reference Book, first published in 1945, maintains its original aims: to reflect the state of the art in electrical science and technology and cater for the needs of practising engineers. Most chapters have been revised and many augmented so as to deal properly with both fundamental developments and new technology and applications that have come to the fore since

Seksuaalisuus ja syöpä : Gynekologista syöpää sairastavan naisen seksuaalisuuden kohtaaminen

OpenAIRE

Mustonen, Niina; Virtanen, Anni

2011-01-01

Tämän opinnäytetyön tarkoituksena on selvittää miten gynekologiseen syöpään sairastuminen ja sen erilaiset hoitomuodot vaikuttavat naisen seksuaalisuuteen. Työn tavoitteena on luoda valmiuksia tuleville hoitoalan ammattilaisille kohdata työssään gynekologista syöpää sairastavan naisen seksuaalisuus. Opinnäytetyön tuotoksena on sähköinen verkkomateriaali syöpäpotilaan seksuaalisuuden kohtaamisesta Tampereen ammattikorkeakoulun opiskelijoille itsenäisen opiskelun tueksi. Työn teoriaosuudess...

The electric power engineering handbook electric power generation, transmission, and distribution

CERN Document Server

Grigsby, Leonard L

2012-01-01

Featuring contributions from worldwide leaders in the field, the carefully crafted Electric Power Generation, Transmission, and Distribution, Third Edition (part of the five-volume set, The Electric Power Engineering Handbook) provides convenient access to detailed information on a diverse array of power engineering topics. Updates to nearly every chapter keep this book at the forefront of developments in modern power systems, reflecting international standards, practices, and technologies. Topics covered include: * Electric Power Generation: Nonconventional Methods * Electric Power Generation

The potential for buoyant displacement gas release events in Tank 241-SY-102 after waste transfer from Tank 241-SY-101

International Nuclear Information System (INIS)

Wells, BE; Meyer, P.E.; Chen, G.

2000-01-01

Tank 241-SY-101 (SY-101) is a double-shell, radioactive waste storage tank with waste that, before the recent transfer and water back-dilution operations, was capable of retaining gas and producing buoyant displacement (BD) gas release events (GREs). Some BD GREs caused gas concentrations in the tank headspace to exceed the lower flammability limit (LFL). A BD GRE occurs when a portion of the nonconvective layer retains enough gas to become buoyant, rises to the waste surface, breaks up, and releases some of its stored gas. The installation of a mixer pump in 1993 successfully mitigated gas retention in the settled solids layer in SY-101 and has since prevented BD GREs. However, operation of the mixer pump over the years caused gas retention in the floating crust layer and a corresponding accelerated waste level growth. The accelerating crust growth trend observed in 1997--98 led to initiation of sequences of waste removal and water back-dilutions in December 1999. Waste is removed from the mixed slurry layer in Tank SY-101 and transferred into Tank 241-Sy-102 (SY-102). Water is then added back to dissolve soluble solids that retain gas. The initial transfer of 89,500 gallons of SY-101 waste, diluted in-line at 0.94:1 by volume with water, to SY-102 was conducted in December 1999. The second transfer of 230,000 gallons of original SY-101 waste, diluted approximately 0.9:1, was completed in January 2000, and the third transfer of 205,500 gallons of original SY-101 waste diluted at 0.9:1 was completed in March 2000

Interactive learning software for electrical engineering subjects ...

African Journals Online (AJOL)

Interactive learning software for electrical engineering subjects using MATLAB and ... Keywords: electrical engineering; MATLAB; graphic user interface (GUI); educational software. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

2012 International Conference on Electrical and Electronics Engineering

CERN Document Server

Chen, Suting; Wei, Zhanming; Xia, Jingming

2014-01-01

Unifying Electrical Engineering and Electronics Engineering is based on the Proceedings of the 2012 International Conference on Electrical and Electronics Engineering (ICEE 2012). This book collects the peer reviewed papers presented at the conference. The aim of the conference is to unify the two areas of Electrical and Electronics Engineering. The book examines trends and techniques in the field as well as theories and applications. The editors have chosen to include the following topics; biotechnology, power engineering, superconductivity circuits, antennas technology, system architectures and telecommunication.

ELECTRICAL TECHNIQUES FOR ENGINEERING APPLICATIONS.

Science.gov (United States)

Bisdorf, Robert J.

1985-01-01

Surface electrical geophysical methods have been used in such engineering applications as locating and delineating shallow gravel deposits, depth to bedrock, faults, clay zones, and other geological phenomena. Other engineering applications include determining water quality, tracing ground water contaminant plumes and locating dam seepages. Various methods and electrode arrays are employed to solve particular geological problems. The sensitivity of a particular method or electrode array depends upon the physics on which the method is based, the array geometry, the electrical contrast between the target and host materials, and the depth to the target. Each of the available electrical methods has its own particular advantages and applications which the paper discusses.

Computer-Aided Engineering for Electric-Drive Vehicle Batteries (CAEBAT)

Science.gov (United States)

Consortium and Partners | Transportation Research | NREL Computer-Aided Engineering for Electric-Drive Vehicle Batteries (CAEBAT) Consortium and Partners Computer-Aided Engineering for Electric -Drive Vehicle Batteries (CAEBAT) Consortium and Partners The Computer-Aided Engineering for Electric

Code of Ethics for Electrical Engineers

Science.gov (United States)

Matsuki, Junya

The Institute of Electrical Engineers of Japan (IEEJ) has established the rules of practice for its members recently, based on its code of ethics enacted in 1998. In this paper, first, the characteristics of the IEEJ 1998 ethical code are explained in detail compared to the other ethical codes for other fields of engineering. Secondly, the contents which shall be included in the modern code of ethics for electrical engineers are discussed. Thirdly, the newly-established rules of practice and the modified code of ethics are presented. Finally, results of questionnaires on the new ethical code and rules which were answered on May 23, 2007, by 51 electrical and electronic students of the University of Fukui are shown.

Computer system requirements specification for 101-SY hydrogen mitigation test project data acquisition and control system (DACS-1)

International Nuclear Information System (INIS)

McNeece, S.G.; Truitt, R.W.

1994-01-01

The system requirements specification for SY-101 hydrogen mitigation test project (HMTP) data acquisition and control system (DACS-1) documents the system requirements for the DACS-1 project. The purpose of the DACS is to provide data acquisition and control capabilities for the hydrogen mitigation testing of Tank SY-101. Mitigation testing uses a pump immersed in the waste, directed at varying angles and operated at different speeds and time durations. Tank and supporting instrumentation is brought into the DACS to monitor the status of the tank and to provide information on the effectiveness of the mitigation test. Instrumentation is also provided for closed loop control of the pump operation. DACS is also capable for being expanded to control and monitor other mitigation testing. The intended audience for the computer system requirements specification includes the SY-101 hydrogen mitigation test data acquisition and control system designers: analysts, programmers, instrument engineers, operators, maintainers. It is intended for the data users: tank farm operations, mitigation test engineers, the Test Review Group (TRG), data management support staff, data analysis, Hanford data stewards, and external reviewers

Christo Beyers-Sy Tydgenote en Geskrifte

African Journals Online (AJOL)

9 Mrt. 1974 ... en dan kyk na die bydrae wat hy, as akadernikus, na- vorser ... In 1908 lewer Beyers 'n lesing getitel 'The origin of .... Brown. Sy was 'n Franse dame,. Mira Rivet, wat Beyers gedurende sy studies in Lon~~n ontmoet het.

Electrical principles and technology for engineering

CERN Document Server

Bird, John

1995-01-01

The aim of this book is to introduce students to the basic electrical and electronic principles needed by technicians in fields such as electrical engineering, electronics and telecommunications. The emphasis is on the practical aspects of the subject, and the author has followed his usual successful formula, incorporating many worked examples and problems (answers supplied) into the learning process.Electrical Principles and Technology for Engineering is John Bird's core text for Further Education courses at BTEC levels N11 and N111 and Advanced GNVQ. It is also designed to provide a comprehe

Waste behavior analysis for tank 241-SY-103

International Nuclear Information System (INIS)

Wilkins, N.E.

1994-01-01

Tank 241-SY-103 is on the Flammable Gas Watch List. The waste in this tank behaves similarly to that in tank 241-Sy-101. Both show slurry growth and periodic surface level drops. However, the surface level drops are much smaller than those in tank 101-SY. A standard hydrogen monitoring system (SHMS) was recently installed in tank 103-SY, and waste auger samples were recently taken. This document covers the characterization results to date for the auger samples, and the behavior of the tank waste during both steady state periods and gas release events

Engineering Electricity Markets for a Decarbonized Energy System

DEFF Research Database (Denmark)

Jenle, Rasmus Ploug; Pallesen, Trine

Decarbonization of the Danish electricity sector has recently been sought achieved through the introduction of a novel retail electricity market, named EcoGrid, designed to create price responsive consumers. By following the market design process undertaken by engineers at the Technical Universit...... of introducing synthetic markets as means of governance.......Decarbonization of the Danish electricity sector has recently been sought achieved through the introduction of a novel retail electricity market, named EcoGrid, designed to create price responsive consumers. By following the market design process undertaken by engineers at the Technical University...... of Denmark, the analysis addresses the question: how do engineers make markets? The answer to this question as presented here is: engineers design control systems. By tracing the origins of EcoGrid, this paper documents the governing of electricity consumers through a ‘synthetic market’, i.e. a market...

SyGuS-Comp 2016: Results and Analysis

Directory of Open Access Journals (Sweden)

Rajeev Alur

2016-11-01

Full Text Available Syntax-Guided Synthesis (SyGuS is the computational problem of finding an implementation f that meets both a semantic constraint given by a logical formula φ in a background theory T, and a syntactic constraint given by a grammar G, which specifies the allowed set of candidate implementations. Such a synthesis problem can be formally defined in SyGuS-IF, a language that is built on top of SMT-LIB. The Syntax-Guided Synthesis Competition (SyGuS-Comp is an effort to facilitate, bring together and accelerate research and development of efficient solvers for SyGuS by providing a platform for evaluating different synthesis techniques on a comprehensive set of benchmarks. In this year's competition we added a new track devoted to programming by examples. This track consisted of two categories, one using the theory of bit-vectors and one using the theory of strings. This paper presents and analyses the results of SyGuS-Comp'16.

Electrical engineering yearbook 95. Data, facts, trends. 14. ed.

International Nuclear Information System (INIS)

Gruetz, A.

1994-01-01

The 'Electrical Engineering Yearbook' in its 14th edition, contains eight chapters with current contributions from reputable expert authors, which give information from practice on the following main subjects: - Communication; -Data networks; - Micro-electronics; - Electromagnetic compatibility; -Overvoltage protection; - VDE guide; - The electrical industry in the German Federal Republic in 1993; - The electricity economy in the German Federal Republic; - Calendar, special dates for electrical engineering, dates of events in 1995. Practical experts again inform their colleagues and interested laymen in the 'Electrical Engineering Yearbook 95' on current data, important circumstances and significant developments . (orig.) [de

Powertrain sizing of electrically supercharged internal combustion engine vehicles

NARCIS (Netherlands)

Murgovski, N.; Marinkov, S.; Hilgersom, D.; de Jager, B.; Steinbuch, M.; Sjöberg, J.

2015-01-01

We assess the concept of electrically supercharged internal combustion engines, where the supercharger, consisting of a compressor and an electric motor, draws electric power from a buffer (a battery or a supercapacitor). In particular, we investigate the scenario of downsizing the engine, while

Engineer/constructor description of work for Tank 241-SY-102 retrieval system, project W-211, initial tank retrieval systems

International Nuclear Information System (INIS)

Rieck, C.A.

1996-02-01

This document provides a description of work for the design and construction of a waste retrieval system for Tank 241-SY-102. The description of work includes a working estimate and schedule, as well as a narrative description and sketches of the waste retrieval system. The working estimate and schedule are within the established baselines for the Tank 241-SY-102 retrieval system. The technical baseline is provided in Functional Design Criteria, WHC-SD-W211-FDC-001, Revision 2

An Operational Standpoint in Electrical Engineering

Directory of Open Access Journals (Sweden)

Frédéric Rotella

2013-12-01

Full Text Available In electrical engineering education exists a major difficulty for first level students, namely the Laplace transform. The question is: does this ubiquitous tool is needed in an electrical engineering course? Our answer is: Obviously, not. Based on an operational standpoint the paper describes some guidelines and results for a primer on handling signals and linear systems without using the Laplace transform. The main advantage is that the operational standpoint leads to simplified proofs for well-known results.

Measuring Technology and Mechatronics Automation in Electrical Engineering

CERN Document Server

2012-01-01

Measuring Technology and Mechatronics Automation in Electrical Engineering includes select presentations on measuring technology and mechatronics automation related to electrical engineering, originally presented during the International Conference on Measuring Technology and Mechanatronics Automation (ICMTMA2012). This Fourth ICMTMA, held at Sanya, China, offered a prestigious, international forum for scientists, engineers, and educators to present the state of the art of measuring technology and mechatronics automation research.

Ultrasonic Examination of Double-Shell Tank 241-SY-103. Examination completed February 2004

International Nuclear Information System (INIS)

Pardini, Allan F.; Posakony, Gerald J.

2004-01-01

COGEMA Engineering Corporation (COGEMA), under a contract from CH2M Hill Hanford Group (CH2M Hill), has performed an ultrasonic nondestructive examination of selected portions of Double-Shell Tank 241-SY-103. The purpose of this examination was to provide information that could be used to evaluate the integrity of the wall of the primary tank. The requirements for the ultrasonic examination of Tank 241-SY-103 were to detect, characterize (identify, size, and locate), and record measurements made of any wall thinning, pitting, or cracks that might be present in the wall of the primary tank. Any measurements that exceed the requirements set forth in the Engineering Task Plan (ETP), RPP-17750 (Jensen 2003) and summarized on page 1 of this document, are reported to CH2M Hill and the Pacific Northwest National Laboratory (PNNL) for further evaluation. Under the contract with CH2M Hill, all data is to be recorded on disk and paper copies of all measurements are provided to PNNL for third-party evaluation. PNNL is responsible for preparing a report that describes the results of the COGEMA ultrasonic examinations

Ultrasonic Examination of Double-Shell Tank 241-SY-102. Examination Completed June 2004

International Nuclear Information System (INIS)

Pardini, Allan F.; Posakony, Gerald J.

2004-01-01

COGEMA Engineering Corporation (COGEMA), under a contract from CH2M Hill Hanford Group (CH2M Hill), has performed an ultrasonic nondestructive examination of selected portions of Double-Shell Tank 241-SY-102. The purpose of this examination was to provide information that could be used to evaluate the integrity of the wall of the primary tank. The requirements for the ultrasonic examination of Tank 241-SY-102 were to detect, characterize (identify, size, and locate), and record measurements made of any wall thinning, pitting, or cracks that might be present in the wall of the primary tank. Any measurements that exceed the requirements set forth in the Engineering Task Plan (ETP), RPP-17750 (Jensen 2003) and/SUMmarized on page 1 of this document, are reported to CH2M Hill and the Pacific Northwest National Laboratory (PNNL) for further evaluation. Under the contract with CH2M Hill, all data is to be recorded on disk and paper copies of all measurements are provided to PNNL for third-party evaluation. PNNL is responsible for preparing a report that describes the results of the COGEMA

78 FR 72552 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2013-12-03

... Airworthiness Directives; General Electric Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA... General Electric Company model GEnx-2B67 and GEnx-2B67B turbofan engines. This AD was prompted by the... certain serial number General Electric Company (GE) model GEnx-2B67 and GEnx-2B67B turbofan engines. The...

Boundary element methods for electrical engineers

CERN Document Server

POLJAK, D

2005-01-01

In the last couple of decades the Boundary Element Method (BEM) has become a well-established technique that is widely used for solving various problems in electrical engineering and electromagnetics. Although there are many excellent research papers published in the relevant literature that describe various BEM applications in electrical engineering and electromagnetics, there has been a lack of suitable textbooks and monographs on the subject. This book presents BEM in a simple fashion in order to help the beginner to understand the very basic principles of the method. It initially derives B

Similarity analysis applied to the design of scaled tests of hydraulic mitigation methods for Tank 241-SY-101

International Nuclear Information System (INIS)

Liljegren, L.M.

1993-02-01

The episodic gas releases from Tank 241-SY-101 (SY-101) pose a potential safety hazard. It is thought that gas releases occur because gases are generated and trapped in layers of settled solids located at the bottom of the tank. This document focuses on issues associated with testing of hydraulic mitigation technologies proposed for SY-101. The basic assumption underlying the concept of hydraulic mitigation is that mobilization or maintained suspension of the solids settled in the bottom of the tank wig prevent gas accumulation. Engineering of hydraulic technologies will require testing to determine the operating parameters required to mobilize the solids and to maintain these solids in suspension. Because full scale testing is extremely expensive (even when possible), scaled tests are needed to assess the merit of the proposed technologies and to provide data for numerical or analytical modeling. This research is conducted to support testing and evaluation of proposed hydraulic mitigation concepts only. The work here is oriented towards determining the jet velocities, nozzle sizes, and other operating parameters required to mobilize the settled solids in SY- 101 and maintain them in suspension

Electrical power cable engineering

CERN Document Server

Thue, William A

2011-01-01

Fully updated, Electrical Power Cable Engineering, Third Edition again concentrates on the remarkably complex design, application, and preparation methods required to terminate and splice cables. This latest addition to the CRC Press Power Engineering series covers cutting-edge methods for design, manufacture, installation, operation, and maintenance of reliable power cable systems. It is based largely on feedback from experienced university lecturers who have taught courses on these very concepts.The book emphasizes methods to optimize vital design and installation of power cables used in the

Electric power substations engineering

CERN Document Server

2003-01-01

This book covers all aspects of substations, from the initial concept to design, automation, operation, and physical and cyber security. Written by members of the Institute of Electrical and Electronic Engineers (IEEE) Power Engineering Society (PES) Substations Committee, each section provides a tutorial and includes references for further reading and study. The authors use photographs and graphics to help the reader understand the material. Exploring the most recent technological developments regarding industry practice and standards, the book provides an extensive overview of substations th

Hazard evaluation for transfer of waste from tank 241-SY-101 to tank 241-SY-102

International Nuclear Information System (INIS)

Shultz, M.V.

1999-01-01

Tank 241-SY-101 waste level growth is an emergent, high priority issue. The purpose of this document is to record the hazards evaluation process and document potential hazardous conditions that could lead to the release of radiological and toxicological material from the proposed transfer of a limited quantity (approximately 100,000 gallons) of waste from Tank 241-SY-101 to Tank 241-SY-102. The results of the hazards evaluation were compared to the current Tank Waste Remediation System (TWRS) Basis for Interim Operation (HNF-SD-WM-BIO-001, 1998, Revision 1) to identify any hazardous conditions where Authorization Basis (AB) controls may not be sufficient or may not exist. Comparison to LA-UR-92-3196, A Safety Assessment for Proposed Pump Mixing Operations to Mitigate Episodic Gas Releases in Tank 241-SY-101, was also made in the case of transfer pump removal activities. Revision 1 of this document deletes hazardous conditions no longer applicable to the current waste transfer design and incorporates hazardous conditions related to the use of an above ground pump pit and overground transfer line. This document is not part of the AB and is not a vehicle for requesting authorization of the activity; it is only intended to provide information about the hazardous conditions associated with this activity. The AB Control Decision process will be used to determine the adequacy of controls and whether the proposed activity is within the AB. This hazard evaluation does not constitute an accident analysis

Desulfurization of dibenzothiophene by Corynebacterium sp. strain SY1

International Nuclear Information System (INIS)

Omori, Toshio; Monna, L.; Saiki, Yuko; Kodama, Tohru

1992-01-01

Strain SY1, identified as a Corynebacterium sp., was isolated on the basis of the ability to utilize dibenzothiophene (DBT) as a sole source of sulfur. Strain SY1 could utilize a wide range of organic and inorganic sulfur compounds, such as DBT sulfone, dimethyl sulfide, dimethyl sulfoxide, dimethyl sulfone, CS 2 , FeS 2 , and even elemental sulfur. Strain SY1 metabolized DBT to dibenzothiophene-5-oxide, DBT sulfone, and 2-hydroxybiphenyl, which was subsequently nitrated to produce at least two different hydroxynitrobiphenyls during cultivation. These metabolites were separated by silica gel column chromatography and identified by nuclear magnetic resonance, UV, and mass spectral techniques. Resting cells of SY1 desulfurized toluenesulfonic acid and released sulfite anion. On the basis of these results, a new DBT degradation pathway is proposed

Die voorsienigheidsleer van Calvyn: Uit sy debatte

Directory of Open Access Journals (Sweden)

Morné Diedericks

2014-09-01

Full Text Available Calvyn se leer van God se voorsienigheid is ongetwyfeld een van die mees kontroversiële onderwerpe van sy teologie. Dit word duidelik in al die debatte waarin Calvyn sy leer oor die voorsienigheid moes verdedig, byvoorbeeld teen Pighius, Bolsec, Bullinger en Castellio. Vyfhonderd jaar later word Calvyn weer in die openbaar oor sy voorsienigheidsleer aangeval deur ’n Suid-Afrikaanse teoloog, Adrio König. Calvyn se antwoord op Castellio in Die verborge voorsienigheid van God is duidelik nie deur König in ag geneem nie. In Calvyn se verdediging van sy voorsienigheidsleer verwerp hy nooit die soewereiniteit van God nie, maar gee ook nie vir God die skuld vir die kwaad nie – ’n beskuldiging wat Castellio en König teen Calvyn inbring. Die troos van God se voorsienigheid lê vir Calvyn juis daarin dat God alle dinge, ook teenspoed en verdrukking, deur sy verborge voorsienigheid beskik met die doel om sy kinders nader na Hom te lei. Calvin’s teaching on providence: From his debates. Calvin’s teaching on God’s providence is without doubt one of the most controversial subjects in his theology. This is clear in all the debates in which Calvin had to defend his teaching on providence, against, for example, Pighius, Bolsec, Bullinger and Castellio. Five hundred years later Calvin has again been publicly attacked on his teaching on providence by a South African theologian, Adrio König. König, however, did not consider Calvin’s response to Castellio in The secret providence of God. In Calvin’s defence of his teaching on providence he in no circumstances denies the sovereignty of God, but also does not give God the blame for any ills that might result – an accusation that Castellio and König levied against him. For Calvin, the consolation of God’s providence rests in the fact that God ordains all things, including adversity and affliction, through his secret providence for the purpose of leading his children closer to him.

Computer-Aided Engineering for Electric-Drive Vehicle Batteries (CAEBAT) |

Science.gov (United States)

Transportation Research | NREL Computer-Aided Engineering for Electric-Drive Vehicle Batteries (CAEBAT) Computer-Aided Engineering for Electric-Drive Vehicle Batteries (CAEBAT) Graphic of a 24-cell (bottom). Images: Courtesy of EC Power NREL's work on the U.S. Department of Energy Computer-Aided

Toimintaterapian mahdollisuudet syöpätautien vuodeosastoilla

OpenAIRE

Nurmi, Mirka; Ohlgren, Sanna; Välimäki, Petra

2011-01-01

Syöpäpotilaiden määrä on kasvanut jatkuvasti ja tulee lisääntymään väistämättä väestön ikääntyessä. On arvioitu, että Suomessa syöpään sairastuu vuonna 2020 yli 33 000 ihmistä, joka on 27 % enemmän kuin vuonna 2008. Mahdollisuus toimia on yksi ihmisen perustarpeista ja syöpään sairastuminen vaikuttaa ihmisen toiminnallisuuteen monilla eri tavoilla. Sairastuminen tai vammautuminen saattaa johtaa tilanteeseen, jossa ihmisen on mahdotonta suoriutua arvostamistaan toiminnoista omassa elämässään. ...

Program For Engineering Electrical Connections

Science.gov (United States)

Billitti, Joseph W.

1990-01-01

DFACS is interactive multiuser computer-aided-engineering software tool for system-level electrical integration and cabling engineering. Purpose of program to provide engineering community with centralized data base for putting in and gaining access to data on functional definition of system, details of end-circuit pinouts in systems and subsystems, and data on wiring harnesses. Objective, to provide instantaneous single point of interchange of information, thus avoiding error-prone, time-consuming, and costly shuttling of data along multiple paths. Designed to operate on DEC VAX mini or micro computer using Version 5.0/03 of INGRES.

241-SY Tank Farm Construction Extent of Condition Review for Tank Integrity

Energy Technology Data Exchange (ETDEWEB)

Barnes, Travis J.; Boomer, Kayle D.; Gunter, Jason R.; Venetz, Theodore J.

2013-07-25

This report provides the results of an extent of condition construction history review for tanks 241-SY-101, 241-SY-102, and 241-SY-103. The construction history of the 241-SY tank farm has been reviewed to identify issues similar to those experienced during tank 241-AY-102 construction. Those issues and others impacting integrity are discussed based on information found in available construction records, using tank 241-AY-102 as the comparison benchmark. In the 241-SY tank farm, the third DST farm constructed, refractory quality and stress relief were improved, while similar tank and liner fabrication issues remained.

Innovative technologies in course Electrical engineering and electronics

Science.gov (United States)

Kuznetsov, E. V.; Kiselev, V. I.; Kulikova, E. A.

2017-11-01

Department of Electrical Engineering and Nondestructive Testing, NRU “MPEI”, has been working on development Electronic Learning Resources (ELRs) in course Electrical Engineering and Electronics for several years. This work have been focused on education intensification and effectiveness while training bachelors in nonelectrical specializations including students from Thermal and Atomic Power Engineering Institute. The developed ELRs are united in a tutorial module consisting of three parts (Electrical Circuits, Electrical Machines, Basics of Electronics): electronic textbook and workbook (ETW); virtual laboratory sessions (VLS); training sessions (ETS); personal tasks (PT); testing system that contains electronic tests in all course subjects and built-in verification of a student’s work results in ETW, VLS, ETS, PT. The report presents samples of different ELRs in html format and MathCAD, MatLAB Simulink applications, copyrighted programs in Java2, Delphi, VB6, C++. The report also contains the experience description, advantages and disadvantages of the new technologies. It is mentioned that ELRs provide new opportunities in course studying.

78 FR 76045 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2013-12-16

... Airworthiness Directives; General Electric Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA... (AD) for General Electric Company (GE) GE90-110B1 and GE90-115B turbofan engines with certain high... turbofan engines with high pressure compressor (HPC) rotor stage 2-5 spools, part numbers (P/Ns) 351-103...

78 FR 50320 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2013-08-19

... Airworthiness Directives; General Electric Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA... Electric Company (GE) model GEnx-2B67B turbofan engines with booster anti-ice (BAI) air duct, part number...-2B67 turbofan engine be removed from the Applicability section of this AD. The commenters noted that...

77 FR 3088 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2012-01-23

... Airworthiness Directives; General Electric Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA... Electric Company (GE) CF34-10E series turbofan engines. This AD was prompted by a report of heavy wear... turbofan engines installed on airplanes of U.S. registry. We also estimate that it will take about 8 work...

Scientific Computing in Electrical Engineering

CERN Document Server

Amrhein, Wolfgang; Zulehner, Walter

2018-01-01

This collection of selected papers presented at the 11th International Conference on Scientific Computing in Electrical Engineering (SCEE), held in St. Wolfgang, Austria, in 2016, showcases the state of the art in SCEE. The aim of the SCEE 2016 conference was to bring together scientists from academia and industry, mathematicians, electrical engineers, computer scientists, and physicists, and to promote intensive discussions on industrially relevant mathematical problems, with an emphasis on the modeling and numerical simulation of electronic circuits and devices, electromagnetic fields, and coupled problems. The focus in methodology was on model order reduction and uncertainty quantification. This extensive reference work is divided into six parts: Computational Electromagnetics, Circuit and Device Modeling and Simulation, Coupled Problems and Multi‐Scale Approaches in Space and Time, Mathematical and Computational Methods Including Uncertainty Quantification, Model Order Reduction, and Industrial Applicat...

Tank SY-101 void fraction instrument functional design criteria

International Nuclear Information System (INIS)

McWethy, L.M.

1994-01-01

This document presents the functional design criteria for design, analysis, fabrication, testing, and installation of a void fraction instrument for Tank SY-101. This instrument will measure the void fraction in the waste in Tank SY-101 at various elevations

77 FR 4650 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2012-01-31

... Airworthiness Directives; General Electric Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA... General Electric Company (GE) CF6-45 and CF6-50 series turbofan engines with certain low-pressure turbine... Compliance We estimate that this AD will affect 387 CF6-45 and CF6-50 series turbofan engines installed on...

78 FR 72567 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2013-12-03

... Airworthiness Directives; General Electric Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA... General Electric Company (GE) GE90-110B1 and -115B turbofan engines. This AD was prompted by multiple... turbofan engines with variable bypass valve (VBV) actuator fuel supply tube, part number (P/N) 2165M22P01...

78 FR 38195 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2013-06-26

... Directives; General Electric Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA), DOT... all General Electric Company (GE) GE90-110B1 and GE90-115B turbofan engines. This emergency AD was.... owners and operators of these GE90-110B1 and GE90-115B turbofan engines. This action was prompted by...

Advances in communication systems and electrical engineering

CERN Document Server

Huang, Xu

2008-01-01

This volume contains contributions from participants in the 2007 International Multiconference of Engineers and Computer Scientists Topics covered include communications theory, communications protocols, network management, wireless networks, telecommunication, electronics, power engineering, control engineering, signal processing, and industrial applications. The book will offer the states of arts of tremendous advances in communication systems and electrical engineering and also serve as an excellent reference work for researchers and graduate students working with/on communication systems a

International conference in electrical engineering and intelligent systems

CERN Document Server

Gelman, Len; Electrical Engineering and Intelligent Systems

2013-01-01

The revised and extended papers collected in this volume represent the cutting-edge of research at the nexus of electrical engineering and intelligent systems. They were selected from well over 1000 papers submitted to the high-profile international World Congress on Engineering held in London in July 2011. The chapters cover material across the full spectrum of work in the field, including computational intelligence, control engineering, network management, and wireless networks. Readers will also find substantive papers on signal processing, Internet computing, high performance computing, and industrial applications.   The Electrical Engineering and Intelligent Systems conference, as part of the 2011 World Congress on Engineering was organized under the auspices of the non-profit International Association of Engineers (IAENG). With more than 30 nations represented on the conference committees alone, the Congress features the best and brightest scientific minds from a multitude of disciplines related to eng...

78 FR 56594 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2013-09-13

... Airworthiness Directives; General Electric Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA... General Electric Company (GE) GE90-76B, -85B, -90B, -94B, -110B1, and - 115B turbofan engines. This AD was...) Applicability This AD applies to General Electric Company (GE): (1) GE90-76B, -85B, -90B, and -94B turbofan...

78 FR 47534 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2013-08-06

... Airworthiness Directives; General Electric Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA... directive (AD) 2013-14-51 for General Electric Company (GE) GE90-110B1 and GE90-115B turbofan engines with... all known U.S. owners and operators of GE90-110B1 and GE90-115B turbofan engines. AD 2013-14-51...

78 FR 24671 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2013-04-26

... Airworthiness Directives; General Electric Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA... certain General Electric Company (GE) CF6-80C2 series turbofan engines. That AD currently requires.../B1F/B2F/B4F/B6F/B7F/D1F turbofan engines with any of the following installed: (1) Fuel tube, part...

78 FR 19983 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2013-04-03

... Airworthiness Directives; General Electric Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA... Electric Company (GE) CF34-8C and CF34-8E turbofan engines with certain part numbers (P/N) of operability...-8E6, and CF34-8E6A1 turbofan engines, with an operability bleed valve (OBV) part number (P/N...

ECTA/DaSy Framework Self-Assessment Comparison Tool

Science.gov (United States)

Center for IDEA Early Childhood Data Systems (DaSy), 2016

2016-01-01

The Self-Assessment Comparison (SAC) Tool is for state Part C and Section 619/Preschool programs to use to assess changes in the implementation of one or more components of the ECTA System Framework and/or subcomponenets of the DaSy Data System Framework. It is a companion to the ECTA/DaSy Framework Self-Assessment. Key features of the SAC are…

Evaluation and suggestions for optional electrical engineering classes curriculum changes in elementary school

OpenAIRE

Štulac, Anja

2014-01-01

The aim of the thesis is to make a survey about teaching of elective subject in the 8th or 9th grade named electrical engineering. The findings could be helpful to teachers of electrical engineering, engineering and technology, physics, as well as for amateur electrical engineering enthusiasts. It is also aimed at those who seek to make changes in the optional electrical engineering course curriculum which represents a plan of work for teachers of this course. It is therefore an important fac...

Convex modeling and sizing of electrically supercharged internal combustion engine powertrain

NARCIS (Netherlands)

Marinkov, S.; Murgovski, N.; de Jager, B.

2016-01-01

This paper investigates a concept of an electrically supercharged internal combustion engine powertrain. A supercharger consists of an electric motor and a compressor. It draws its power from an electric energy buffer (e.g., a battery) and helps the engine during short-duration high-power demands.

Influence of electrical resistivity and machining parameters on electrical discharge machining performance of engineering ceramics.

Science.gov (United States)

Ji, Renjie; Liu, Yonghong; Diao, Ruiqiang; Xu, Chenchen; Li, Xiaopeng; Cai, Baoping; Zhang, Yanzhen

2014-01-01

Engineering ceramics have been widely used in modern industry for their excellent physical and mechanical properties, and they are difficult to machine owing to their high hardness and brittleness. Electrical discharge machining (EDM) is the appropriate process for machining engineering ceramics provided they are electrically conducting. However, the electrical resistivity of the popular engineering ceramics is higher, and there has been no research on the relationship between the EDM parameters and the electrical resistivity of the engineering ceramics. This paper investigates the effects of the electrical resistivity and EDM parameters such as tool polarity, pulse interval, and electrode material, on the ZnO/Al2O3 ceramic's EDM performance, in terms of the material removal rate (MRR), electrode wear ratio (EWR), and surface roughness (SR). The results show that the electrical resistivity and the EDM parameters have the great influence on the EDM performance. The ZnO/Al2O3 ceramic with the electrical resistivity up to 3410 Ω·cm can be effectively machined by EDM with the copper electrode, the negative tool polarity, and the shorter pulse interval. Under most machining conditions, the MRR increases, and the SR decreases with the decrease of electrical resistivity. Moreover, the tool polarity, and pulse interval affect the EWR, respectively, and the electrical resistivity and electrode material have a combined effect on the EWR. Furthermore, the EDM performance of ZnO/Al2O3 ceramic with the electrical resistivity higher than 687 Ω·cm is obviously different from that with the electrical resistivity lower than 687 Ω·cm, when the electrode material changes. The microstructure character analysis of the machined ZnO/Al2O3 ceramic surface shows that the ZnO/Al2O3 ceramic is removed by melting, evaporation and thermal spalling, and the material from the working fluid and the graphite electrode can transfer to the workpiece surface during electrical discharge

THE BLENDED LEARNING OF ELECTRICITY USING LEARNING OBJECTS IN ENGINEERING

Directory of Open Access Journals (Sweden)

Lilia Maria Siqueira

2010-09-01

Full Text Available This work presents a proposal for the blended learning of Electricity education in Engineering, using resources called learning objects. The experience occurred with students enrolled on the Electrical Engineering and Computer Engineering courses at PUCPR University. It made possible the contact with interdisciplinary themes related to the study of electricity and the professional curriculum contents. The learning objects, offered during the semester, were anchored on PUCPR’s proprietary virtual educational environment, called Eureka. The students’ evaluation results showed that the study through learning objects in a virtual environment is significant for learning.

XI Scientific Conference Selected Issues of Electrical Engineering and Electronics (WZEE)

CERN Document Server

Mazur, Damian; Analysis and Simulation of Electrical and Computer Systems

2015-01-01

This book presents the selected results of the XI Scientific Conference Selected Issues of Electrical Engineering and Electronics (WZEE) which was held in Rzeszów and Czarna, Poland on September 27-30, 2013. The main aim of the Conference was to provide academia and industry to discuss and present the latest technological advantages and research results and to integrate the new interdisciplinary scientific circle in the field of electrical engineering, electronics and mechatronics. The Conference was organized by the Rzeszów Division of Polish Association of Theoretical and Applied Electrical Engineering (PTETiS) in cooperation with Rzeszów University of Technology, the Faculty of Electrical and Computer Engineering and Rzeszów University, the Faculty of Mathematics and Natural Sciences.  

Job Prospects for Electrical Engineers.

Science.gov (United States)

Basta, Nicholas

1986-01-01

Discusses the career outlook for electrical/electronics engineers. Explains that the number of bachelor degree graduates continues to rise, along with average starting salaries. Reveals that although the availability of jobs in the computer industry is leveling off, prospects in the robotics and telecommunication fields are growing. (TW)

Electrical circuits in biomedical engineering problems with solutions

CERN Document Server

Keskin, Ali Ümit

2017-01-01

This authored monograph presents a comprehensive and in-depth analysis of electrical circuit theory in biomedical engineering, ideally suited as textbook for a course program. The book contains methods and theory, but the topical focus is placed on practical applications of circuit theory, including problems, solutions and case studies. The target audience primarily comprises researchers and experts in electrical engineering who intend to embark on biomedical applications. The book is also very well suited for graduate students in the field. .

Electric utility engineer`s FGD manual -- Volume 1: FGD process design. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-03-04

Part 1 of the Electric Utility Engineer`s Flue Gas Desulfurization (FGD) Manual emphasizes the chemical and physical processes that form the basis for design and operation of lime- and limestone-based FGD systems applied to coal- or oil-fired steam electric generating stations. The objectives of Part 1 are: to provide a description of the chemical and physical design basis for lime- and limestone-based wet FGD systems; to identify and discuss the various process design parameters and process options that must be considered in developing a specification for a new FGD system; and to provide utility engineers with process knowledge useful for operating and optimizing a lime- or limestone-based wet FGD system.

Status of tank 241-SY-101 data analyses

International Nuclear Information System (INIS)

Anantatmula, R.P.

1992-09-01

The Waste Tank Flammable Gas Stabilization Program was established in 1990 to provide for resolution of a major safety issue identified for 23 of the high-level waste tanks at the Hanford Site. The safety issue involves the production, accumulation, and periodic release from these tanks of flammable gases in concentrations exceeding the lower flammability limits. This document deals primarily with tank 241-SY-101 from the SY Tank Farm. The flammable gas condition has existed for this tank since the tank was first filled in the time period from 1977 to 1980. During a general review of waste tank chemical stability in 1988--1989, this situation was re-examined and, in March 1990, the condition was declared to be an unreviewed safety question. Tank 241-SY-101 was placed under special operating restrictions, and a program of investigation was begun to evaluate the condition and determine appropriate courses of action. This report summarizes the data that have become available on tank 241-SY-101 since it was declared as an unreviewed safety question and updates the information reported in an earlier document (WHC-EP-0517). The report provides a technical basis for use in the evaluation of safety risks of the tank and subsequent resolution of the unreviewed safety question

The fundamentals of electrical engineering for mechatronics

CERN Document Server

Hüning, Felix

2014-01-01

This book covers the basic principles of electrical engineering. The depth of content and presentation is intended for students in the field of mechatronics, especially those with a background in mechanics or mechanical engineering. In addition to theoretical sections and practical applications, the textbook offers numerous practice exercises to apply and deepen the student's learning.

How Engineers Make Markets Organizing Electricity System Decarbonization

DEFF Research Database (Denmark)

Jenle, Rasmus Ploug; Pallesen, Trine

2017-01-01

construction process undertaken by scientists at the Technical University of Denmark, this article shows how engineers have approached the task by designing markets as technical control systems. It is demonstrated that EcoGrid has been designed by modeling a retail electricity market on three different...... conceptions of control systems as found in the discipline of control systems engineering. By tracing the origins of EcoGrid, this article documents the governing of electricity consumers through what we here call a synthetic market, i.e. a market artifact devised to attain goals. These findings about...

Advances in Electrical Engineering and Automation

CERN Document Server

Huang, Xiong

2012-01-01

EEA2011 is an integrated conference concentration its focus on Electrical Engineering and Automation. In the proceeding, you can learn much more knowledge about  Electrical Engineering and Automation of researchers from all around the world. The main role of the proceeding is to be used as an exchange pillar for researchers who are working in the mentioned fields. In order to meet the high quality of Springer, AISC series, the organization committee has made their efforts to do the following things. Firstly, poor quality paper has been refused after reviewing course by anonymous referee experts. Secondly, periodically review meetings have been held around the reviewers about five times for exchanging reviewing suggestions. Finally, the conference organizers had several preliminary sessions before the conference. Through efforts of different people and departments, the conference will be successful and fruitful.  

Electric power engineering in the Taiwan Chinese Republic

International Nuclear Information System (INIS)

Kozlov, V.B.

1992-01-01

The data charaterizing the status and prospects of development of electric power engineering in the Taiwan Chenese Republic are given. The Tainwan electric power consumptions are covered by operation of 56 large electric power plants (nuclear, thermal, hydroelectric ones). The marginal majority (58.1%) of the registered power is generated at thermal power plants. Electric power generation in 1991 amounted to 89639 million kWxh. At that 33878 million kWxh or about 37.9% were produced at NPPs

Knowledge Service Engineering Handbook

CERN Document Server

Kantola, Jussi

2012-01-01

Covering the emerging field of knowledge service engineering, this groundbreaking handbook outlines how to acquire and utilize knowledge in the 21st century. Drawn on the expertise of the founding faculty member of the world's first university knowledge engineering service department, this book describes what knowledge services engineering means and how it is different from service engineering and service production. Presenting multiple cultural aspects including US, Finnish, and Korean, this handbook provides engineering, systemic, industry, and consumer use viewpoints to knowledge service sy

Scientific computing in electrical engineering SCEE 2010

Energy Technology Data Exchange (ETDEWEB)

Michielsen, Bastiaan [Office National d' Etudes et de Recherches Aerospatiales (ONERA), 31 - Toulouse (France); Poirier, Jean-Rene (eds.) [LAPLACE-ENSEEIHT, Toulouse (France)

2012-07-01

Selected from papers presented at the 8th Scientific Computation in Electrical Engineering conference in Toulouse in 2010, the contributions to this volume cover every angle of numerically modelling electronic and electrical systems, including computational electromagnetics, circuit theory and simulation and device modelling. On computational electromagnetics, the chapters examine cutting-edge material ranging from low-frequency electrical machine modelling problems to issues in high-frequency scattering. Regarding circuit theory and simulation, the book details the most advanced techniques for modelling networks with many thousands of components. Modelling devices at microscopic levels is covered by a number of fundamental mathematical physics papers, while numerous papers on model order reduction help engineers and systems designers to bring their modelling of industrial-scale systems within the reach of present-day computational power. Complementing these more specific papers, the volume also contains a selection of mathematical methods which can be used in any application domain. (orig.)

Acceptance Test Report for 241-SY Pump Cradle Hydraulic System

International Nuclear Information System (INIS)

Koons, B.M.

1995-01-01

The purpose of this ATP is to verify that hydraulic system/cylinder procured to replace the cable/winch system on the 101-SY Mitigation Pump cradle assembly fulfills its functional requirements for raising and lowering the cradle assembly between 70 and 90 degrees, both with and without pump. A system design review was performed on the 101-SY Cradle Hydraulic System by the vendor before shipping (See WHC-SD-WM-DRR-045, 241-SY-101 Cradle Hydraulic System Design Review). The scope of this plan focuses on verification of the systems ability to rotate the cradle assembly and any load through the required range of motion

Syed Mahmood Naqvi (27 August 1941 - 04 September 2009)

Digital Repository Service at National Institute of Oceanography (India)

Naqvi, S.W.A.; Rao, Y.J.B.

-1 SYED MAHMOOD NAQVI (1941-2009) Elected Fellow 1986 LIFE, EDUCATION AND FAMILY Being a descendent of Prophet Muhammad's daughter Syeda (hence the title 'Syed') through the 10 lh Shia Imam Ali Naqi (hence the surname 'Naqvi'). Mahmood's roots into science... living, something that he was not used to. He was only moderately educated. However, both he and his father wanted Bhni to obtain ...

Engine-start Control Strategy of P2 Parallel Hybrid Electric Vehicle

Science.gov (United States)

Xiangyang, Xu; Siqi, Zhao; Peng, Dong

2017-12-01

A smooth and fast engine-start process is important to parallel hybrid electric vehicles with an electric motor mounted in front of the transmission. However, there are some challenges during the engine-start control. Firstly, the electric motor must simultaneously provide a stable driving torque to ensure the drivability and a compensative torque to drag the engine before ignition. Secondly, engine-start time is a trade-off control objective because both fast start and smooth start have to be considered. To solve these problems, this paper first analyzed the resistance of the engine start process, and established a physic model in MATLAB/Simulink. Then a model-based coordinated control strategy among engine, motor and clutch was developed. Two basic control strategy during fast start and smooth start process were studied. Simulation results showed that the control objectives were realized by applying given control strategies, which can meet different requirement from the driver.

CDIO – The steam engine powering the electric grid

DEFF Research Database (Denmark)

Træholt, Chresten; Holbøll, Joachim; Thomsen, Ole Cornelius

2011-01-01

In building the new DTU B.Eng programme [1] one of the pilots on the 4’th semester is the Design-build project course in Electric Energy Systems. In this course, which is the last Designbuild course many of the CDIO Syllabus bullets [2] are addressed starting with problem identification and formu......In building the new DTU B.Eng programme [1] one of the pilots on the 4’th semester is the Design-build project course in Electric Energy Systems. In this course, which is the last Designbuild course many of the CDIO Syllabus bullets [2] are addressed starting with problem identification...... and formulation, experimental inquiry and modelling, finally leading to planning and solution. The goal is to acquire the skills that are needed for an engineer within electric power engineering to analyse a given task, define the necessary steps to solve the task, organize him/her self and others and finally...... solve the task with success. The concrete work is built up around a miniaturized electric energy system powered by a steam engine. The system mimics an essential sub-section of a real electric power system. The process is realised with a combination of optional lectures, optional exercises, 3 set...

Yue Joseph Wang named Grant A. Dove Professor of Electrical and Computer Engineering

OpenAIRE

Owczarski, Mark

2009-01-01

Yue Joseph Wang, professor of electrical and computer engineering in the College of Engineering at Virginia Tech, has been named the Grant A. Dove Professor of Electrical and Computer Engineering by the Virginia Tech Board of Visitors.

Tank 241-SY-102, January 2000 Compatibility Grab Samples Analytical Results for the Final Report

International Nuclear Information System (INIS)

BELL, K.E.

2000-01-01

This document is the format IV, final report for the tank 241-SY-102 (SY-102) grab samples taken in January 2000 to address waste compatibility concerns. Chemical, radiochemical, and physical analyses on the tank SY-102 samples were performed as directed in Comparability Grab Sampling and Analysis Plan for Fiscal Year 2000 (Sasaki 1999). No notification limits were exceeded. Preliminary data on samples 2SY-99-5, -6, and -7 were reported in ''Format II Report on Tank 241-SY-102 Waste Compatibility Grab Samples Taken in January 2000'' (Lockrem 2000). The data presented here represent the final results

Systems Engineering of Electric and Hybrid Vehicles

Science.gov (United States)

Kurtz, D. W.; Levin, R. R.

1986-01-01

Technical paper notes systems engineering principles applied to development of electric and hybrid vehicles such that system performance requirements support overall program goal of reduced petroleum consumption. Paper discusses iterative design approach dictated by systems analyses. In addition to obvious peformance parameters of range, acceleration rate, and energy consumption, systems engineering also considers such major factors as cost, safety, reliability, comfort, necessary supporting infrastructure, and availability of materials.

A concept for a bachelor program in electrical engineering

DEFF Research Database (Denmark)

Niemann, Hans Henrik

2011-01-01

The main concept for the Bachelor of Science in Engineering (BScE) in electrical engineering at Technical University of Denmark (DTU) will be described in this paper. A new curriculum was introduced from the start of the autumn semester in 2010. The curriculum was the result of more than one year...... of work with first description of competences followed by a more detailed description of the single main areas. Finally, the new study plan was implemented through a number of courses satisfying some general rules for bachelor study plans.......The main concept for the Bachelor of Science in Engineering (BScE) in electrical engineering at Technical University of Denmark (DTU) will be described in this paper. A new curriculum was introduced from the start of the autumn semester in 2010. The curriculum was the result of more than one year...

First International Conference on Electrical, Electronic and Communications Engineering

CERN Document Server

Vyas, Nalinaksh; Sanei, Saeid; Deb, Kalyanmoy

2017-01-01

The book reports on advanced theories and methods in two related engineering fields: electrical and electronic engineering, and communications engineering and computing. It highlights areas of global and growing importance, such as renewable energy, power systems, mobile communications, security and the Internet of Things (IoT). The contributions cover a number of current research issues, including smart grids, photovoltaic systems, wireless power transfer, signal processing, 4G and 5G technologies, IoT applications, mobile cloud computing and many more. Based on the proceedings of the first International Conference on Emerging Trends in Electrical, Electronic and Communications Engineering (ELECOM 2016), held in Voila Bagatelle, Mauritius from November 25 to 27, 2016, the book provides graduate students, researchers and professionals with a snapshot of the state-of-the-art and a source of new ideas for future research and collaborations.

241-SY-101 air lance removal lessons learned

International Nuclear Information System (INIS)

Moore, T.L.; Titzler, P.A.

1994-01-01

An emergency task was undertaken to remove four air lances and one thermocouple (TC) tree from tank 241-SY-101 (SY-101). This resulted from video observation that these pipes were being severely bent during periodic gas release events that regularly occurred every three to four months. At the time, the gas release events were considered to be the number one safety issue within the US Department of Energy (DOE) complex. This emergency removal task was undertaken on an extremely short schedule that required all activities possible to be completed in parallel. This approach and extremely short schedule, while successful, resulted in some undesirable consequences from less than desired time for design, reviews, equipment testing, operations training, and bad weather conditions. These consequences included leakage of liquid waste from the containers to the ground, higher than expected dose rates at the container surface, difficult field operations, and unexpected pipe configuration during removal. In addition, changes to environmental regulations and severe winter weather impacted the packaging and shipping activities required the prepare the removed pipes for storage at the Central Waste Complex (CWC). The purpose of this document is to identify lessons to be learned for future activities. In context of the emergency conditions that existed at the time and the urgency to remove these pipes, their removal was successfully completed under extremely difficult conditions and schedule. The success of the task should not be overshadowed by the desire to identify areas needing improvement and lessons to be learned. Many of the lessons identified in this document have already resulted in improved conduct of operations and engineering

Syed Manzoorul Islam’s Postmodern Tales: A Study

Directory of Open Access Journals (Sweden)

Md Abdul Momen Sarker

2016-10-01

Full Text Available The paper brings into focus how Syed Manzoorul Islam, in his three-decade-long literary career, has mastered a narrative style that sets him apart from many of his Bengali contemporaries. It demonstrates all the traits unique to his storytelling: blurring of boundaries between dream and reality, self-reflexivity, irony, and humor. The research also encapsulates how Syed Islam is different from his contemporary short story writers in terms of constructing plot and character. It foregrounds the author’s capability of developing a diction which is completely his own. The paper discusses the postmodern features prevailing in his stories. It shows us how the author invites the readers to be a part of his discourses. It summarizes the author’s surrealist imagination which creates a world that is strangely familiar and unfamiliar at the same time. Overall, the research analyzes how the postmodern elements relate to the major themes of Syed Manzoorul Islam’s short stories. Keywords: Post-modernism, magic-realism, realism, psychoanalysis, political degeneration

SAFETY ANALYSIS APPROACH TO TANK 241-SY-101 REMEDIATION ACTIVITIES

International Nuclear Information System (INIS)

RYAN, G.W.

2000-01-01

An Unreviewed Safety Question was declared related to the unexplained waste surface level growth in high-level radioactive waste storage Tank 241-SY-101 at the Hanford Site in Richland, Washington. Because the waste surface level in Tank 241-SY-101 was growing in a manner inconsistent with previous behavior, the following issues of concern were recognized: (1) The continually rising surface level had the potential to reach physical encumbrances or limits within the tank (e.g., instrumentation, cameras, established Authorization Basis limits, and the double containment boundary) and the potential to significantly change the consequences of previously analyzed accidents (e.g., flammable gas deflagrations). (2) The presence of new hazards because of significant quantities of flammable gas retained in the crust (e.g., crust collapse gas-release events). (3) The potential to inhibit information gathering related to the existing hazards in the tank (e.g., unable to determine surface level to assess the potential for large gas releases). In response to this situation, a Contractor Project Team, which included Department of Energy representation, was formed to constructively address the issue. The team was responsible for developing and evaluating remediation options and executing the chosen option for remediating the surface level rise issue for Tank 241-SY-101. From an Authorization Basis perspective, the following important aspects will be discussed in this paper: (1) The integrated nature of the Project Team. The team consisted of all the organizations necessary to ensure that the time available to remediate Tank 241-SY-101 was effectively used. Most notable is the connectivity of the Nuclear Safety and Licensing organization with the Engineering, Design, and Operations organizations. (2) The ability of the safety analysis support to adjust to and address evolving Project Team goals and dynamic tank conditions. (3) Due to the urgency to mitigate this developing issue

Research on the Fault Coefficient in Complex Electrical Engineering

Directory of Open Access Journals (Sweden)

Yi Sun

2015-08-01

Full Text Available Fault detection and isolation in a complex system are research hotspots and frontier problems in the reliability engineering field. Fault identification can be regarded as a procedure of excavating key characteristics from massive failure data, then classifying and identifying fault samples. In this paper, based on the fundamental of feature extraction about the fault coefficient, we will discuss the fault coefficient feature in complex electrical engineering in detail. For general fault types in a complex power system, even if there is a strong white Gaussian stochastic interference, the fault coefficient feature is still accurate and reliable. The results about comparative analysis of noise influence will also demonstrate the strong anti-interference ability and great redundancy of the fault coefficient feature in complex electrical engineering.

Stand for testing the electrical race car engine

Science.gov (United States)

Baier, M.; Franiasz, J.; Mierzwa, P.; Wylenzek, D.

2015-11-01

An engine test stand created especially for research of electrical race car is described in the paper. The car is an aim of Silesian Greenpower project whose participants build and test electrical vehicles to take part in international races in Great Britain. The engine test stand is used to test and measure the characteristics of vehicles and their engines. It has been designed particularly to test the electric cars engineered by students of Silesian Greenpower project. The article contains a description how the test stand works and shows its versatility in many areas. The paper presents both construction of the test stand, control system and sample results of conducted research. The engine test stand was designed and modified using PLM Siemens NX 8.5. The construction of the test stand is highly modular, which means it can be used both for testing the vehicle itself or for tests without the vehicle. The test stand has its own wheel, motor, powertrain and braking system with second engine. Such solution enables verifying various concepts without changing the construction of the vehicle. The control system and measurement system are realized by enabling National Instruments product myRIO (RIO - Reconfigurable Input/Output). This controller in combination with powerful LabVIEW environment performs as an advanced tool to control torque and speed simultaneously. It is crucial as far as the test stand is equipped in two motors - the one being tested and the braking one. The feedback loop is realized by an optical encoder cooperating with the rotor mounted on the wheel. The results of tests are shown live on the screen both as a chart and as single values. After performing several tests there is a report generated. The engine test stand is widely used during process of the Silesian Greenpower vehicle design. Its versatility enables powertrain testing, wheels and tires tests, thermal analysis and more.

The effect of dilution on the gas retention behavior of Tank 241-SY- 103 waste

International Nuclear Information System (INIS)

Bredt, P.R.; Tingey, S.M.

1996-01-01

Twenty-five of the 177 underground waste storage tanks on the Hanford Site have been placed on the Flammable Gas watch list. These 25 tanks, containing high-level waste generated during plutonium and uranium processing, have been identified as potentially capable of accumulating flammable gases above the lower flammability limit (Babad et al. 1991). In the case of Tanks 241-SY-101 and 241-SY-103, it has been proposed that diluting the tank waste may mitigate this hazard (Hudson et al. 1995; Stewart et al. 1994). The effect of dilution on the ability of waste from Tank 241-SY-103 to accumulate gas was studied at Pacific Northwest National Laboratory. A similar study has been completed for waste from Tank 241-SY-101 (Bredt et al. 1995). Because of the additional waste-storage volume available in Tank 241-SY-103 and because the waste is assumed to be similar to that currently in Tank 241-SY-101, Tank 241-SY-103 became the target for a demonstration of passive mitigation through in-tank dilution. In 1994, plans for the in-tank dilution demonstration were deferred pending a decision on whether to pursue dilution as a mitigation strategy. However, because Tank 241-SY-103 is an early retrieval target, determination of how waste properties vary with dilution will still be required

Proceedings of seminar on recent trends in generation and utilisation in electrical engineering

International Nuclear Information System (INIS)

1999-01-01

The proceedings of the seminar on recent trends in generation and utilization in electrical engineering is very relevant in the present juncture. The papers have been divided into various sessions corresponding to the different topics of electrical engineering e.g. energy sources; power generation; materials, energy sources, power electronics, UPS and special purpose machines; conservation of energy - variable speed drives and control of P.F.; applications of electrical energy monitoring, protection and lighting; switch-gear, switchyards, control; safety aspects in electrical engineering materials, cables and quality control; applications of computers - expert systems, communication aspects and miscellaneous. Papers relevant to INIS are indexed separately

Legal bases of safety regulations in electrical engineering

Energy Technology Data Exchange (ETDEWEB)

Jeiter, W

1981-12-01

Apart from the governmental regulations the rule for the prevention of accidents 'Electric plants and equipment' must be observed in order to protect the insurants. Actually, all these regulations do not contain any independent instructions. They rather utilize the VDE regulations and refer to them. The laws of electrical safety engineering are strongly influenced by harmonization efforts particularly within the European Communitties.

ATR/OTR-SY Tank Camera Purge System and in Tank Color Video Imaging System

International Nuclear Information System (INIS)

Werry, S.M.

1995-01-01

This procedure will document the satisfactory operation of the 101-SY tank Camera Purge System (CPS) and 101-SY in tank Color Camera Video Imaging System (CCVIS). Included in the CPRS is the nitrogen purging system safety interlock which shuts down all the color video imaging system electronics within the 101-SY tank vapor space during loss of nitrogen purge pressure

76 FR 64844 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2011-10-19

... Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed... General Electric Company (GE) CF6-45 and CF6-50 series turbofan engines with certain low-pressure turbine... series turbofan engines with certain LPT rotor stage 3 disks installed. That AD requires initial and...

78 FR 44899 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2013-07-25

... Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed... Electric Company (GE) GE90-110B1 and -115B turbofan engines. This proposed AD was prompted by multiple...) 2165M22P01, installed on GE90-110B1 and -115B turbofan engines. One of the leaks led to an under cowl engine...

Engineering task plan for steam line ramp calculations

International Nuclear Information System (INIS)

DeSantis, G.N.; Freeman, R.D.

1994-01-01

The purpose of this document is to provide an approved work plan to perform calculations that verify the load limits of a proposed ramp over a steam line at the back side (East side) of SY Farm in support of work package 2W-94-00812/K. The objective of this supporting document is to provide Operations with a set of checked calculations that verify the ramp over the steam line at SY Farm will support a fully loaded concrete mixer truck without affecting the steam line. The calculations will be performed by an engineers from Facility Systems and independently checked and reviewed by another engineer. The calculations may then be added to the work package. If Operations decides to make any configuration changes to the steam line or surrounding area, Operations shall have these changes documented by an Engineering Change Notice (ECN). This ECN can be done by Facility Systems or any other engineering organization at the direction of Operations

78 FR 19628 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2013-04-02

... Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed... Electric Company (GE) GE90-76B, -85B, -90B, -94B, - 110B1, and -115B turbofan engines. This proposed AD was... of stage 1 HPT stator shroud distress resulting in engine removals on airplanes with GE90 turbofan...

77 FR 58471 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2012-09-21

... Airworthiness Directives; General Electric Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA.../P1, GEnx-1B75/P1, GEnx- 2B67, and GEnx-2B67B turbofan engines. This AD requires initial and... this AD will affect 11 GE GEnx turbofan engines installed on airplanes of U.S. registry. We also...

The electric power engineering handbook power systems

CERN Document Server

2012-01-01

Power Systems, Third Edition (part of the five-volume set, The Electric Power Engineering Handbook) covers all aspects of power system protection, dynamics, stability, operation, and control. Under the editorial guidance of L.L. Grigsby, a respected and accomplished authority in power engineering, and section editors Andrew Hanson, Pritindra Chowdhuri, Gerry Sheble, and Mark Nelms, this carefully crafted reference includes substantial new and revised contributions from worldwide leaders in the field. This content provides convenient access to overviews and detailed information on a diverse arr

241-SY-101 DACS instrument problem screen (SCR 448) acceptance test procedure

International Nuclear Information System (INIS)

ERMI, A.M.

1999-01-01

The operability of the 241-SY-101 Data Acquisition and Control System (DACS) to provide proper control and monitoring of the mitigation mixer pump and instrumentation installed in the 241-SY-101 underground storage tank utilizing the [INSTPROB] screen will be systematically evaluated by the performance of this procedure

Isolation and characterization of a plant growth-promoting rhizobacterium, Serratia sp. SY5.

Science.gov (United States)

Koo, So-Yeon; Cho, Kyung-Suk

2009-11-01

The role of plant growth-promoting rhizobacteria (PGPR) in the phytoremediation of heavy-metal-contaminated soils is important in overcoming its limitations for field application. A plant growth-promoting rhizobacterium, Serratia sp. SY5, was isolated from the rhizoplane of barnyard grass (Echinochloa crus-galli) grown in petroleum and heavy-metal-contaminated soil. This isolate has shown capacities for indole acetic acid production and siderophores synthesis. Compared with a non-inoculated control, the radicular root growth of Zea mays seedlings inoculated with SY5 can be increased by 27- or 15.4-fold in the presence of 15 mg-Cd/l or 15 mg-Cu/l, respectively. The results from hydroponic cultures showed that inoculation of Serratia sp. SY5 had a favorable influence on the initial shoot growth and biomass of Zea mays under noncontaminated conditions. However, under Cd-contaminated conditions, the inoculation of SY5 significantly increased the root biomass of Zea mays. These results indicate that Serratia sp. SY5 can serve as a promising microbial inoculant for increased plant growth in heavy-metal-contaminated soils to improve the phytoremediation efficiency.

Biomass gasification for electricity generation with internal combustion engines. Process efficiency

International Nuclear Information System (INIS)

Lesme-Jaén, René; Garcia Faure, Luis; Recio Recio, Angel; Oliva Ruiz, Luis; Pajarín Rodríguez, Juan; Revilla Suarez, Dennis

2015-01-01

Biomass is a renewable source of energy worldwide increased prospects for its potential and its lower environmental impact compared to fossil fuels. By processes and energy conversion technologies it is possible to obtain fuels in solid, liquid and gaseous form from any biomass. The biomass gasification is the thermal conversion thereof into a gas, which can be used for electricity production with the use of internal combustion engines with a certain level of efficiency, which depends on the characteristics of biomass and engines used. In this work the evaluation of thermal and overall efficiency of the gasification in Integrated Forestry Enterprise of Santiago de Cuba, designed to generate electricity from waste from the forest industry is presented. Is a downdraft gasifier reactor, COMBO-80 model and engine manufacturing Hindu (diesel) model Leyland modified to work with producer gas. The evaluation was carried out for different loads (electric power generated) engine from experimental measurements of flow and composition of the gas supplied to the engine. The results show that the motor operates with a thermal efficiency in the range of 20-32% with an overall efficiency between 12-25%. (full text)

Acceptance test procedure, 241-SY-101 Flexible Receiver System, Phase III testing

International Nuclear Information System (INIS)

Ritter, G.A.

1994-01-01

This Acceptance Test Procedure is for the 241-SY-101 Flexible Receiver System, Phase III Testing. This procedure will test the sealing integrity of the Flexible Receiver System to ensure that release of waste and aerosols will be minimized during the removal of the test mixer pump from tank SY-101

Transmission and distribution electrical engineering

CERN Document Server

Bayliss, Colin

2003-01-01

This comprehensive treatment of the theory and practice encountered in the installation and design of transmission and distribution systems for electrical power has been updated and revised to provide the project engineer with all the latest, relevant information to design and specify the correct system for a particular application.Thoroughly updated and revised to include latest developmentsLearn from and Author with extensive experience in managing international projectsFind out the reasoning and implicatons behind the different specifications and methods

Spectrophotometry of the nucleus of the Sy 2 galaxy Markarian 308

International Nuclear Information System (INIS)

Popov, V.N.; Khachikyan, Eh.E.

1980-01-01

The results of spectrophotometry of the Sy2 galaxy Markarian 308 are presented. The profiles of the emission lines [N II] lambda lambda 6583, 6548 A, Hsub(α), [O III] lambda lambda 5007, 4959 A and Hsub(β) are drawn. The electron density, electron temperature, mass and effective volume of the emitting gas are estimated. Markarian 308 shows now less activity compared with other Sy2 galaxies

Hanford's Battle with Nuclear Waste Tank SY-101: Bubbles, Toils, and Troubles

International Nuclear Information System (INIS)

Stewart, Charles W.

2006-01-01

Radioactive waste tank SY-101 is one of 177 big underground tanks that store waste from decades of plutonium production at the Hanford Nuclear Reservation in central Washington State. The chemical reactions and radioactivity in all the tanks make bubbles of flammable gas, mainly hydrogen along with a little methane and ammonia. But SY-101 was the most potent gas producer of all. Every few months the gas built up in the million gallons of extra-thick slurry until it suddenly came up in great rushing ''burps''. A few of the tank's larger burps let off enough gas to make the air space at the top of the tank flammable for a few hours. This flammable gas hazard became a dominating force in DOE nuclear waste management politics in the last two decades of the 20th century. It demanded the toil of scientists, managers, and officials from the time it was filled in 1980, until it was finally declared safe in January 2001. The tank seemed almost a personality--acting with violence and apparent malice, hiding information about itself, deceiving us with false indications, and sometimes lulling us into complacency only to attack in a new way. From 1990 through 1993, SY-101's flammable gas troubles were acknowledged as the highest priority safety issue in the entire DOE complex. Uncontrolled crust growth demanded another high-priority remedial effort from 1998 through April 2000. The direct cost of the bubbles, toils, and troubles was high. Overall, the price of dealing with the real and imagined hazards in SY-101 may have reached $250 million. The indirect cost was also high. Spending all this money fighting SY-101?s safety issues only stirred radioactive waste up and moved it around, but accomplished no cleanup whatever. Worse yet, the flammable gas problem spawned suspicions of a much wider danger that impeded and complicated cleanup in other 176 waste tanks for a decade. The real cleanup job has yet to be done. The SY-101 story is really about the collective experience of

The performance simulation of single cylinder electric power confined piston engine

Science.gov (United States)

Gou, Yanan

2017-04-01

A new type of power plant. i.e, Electric Power Confined Piston Engine, is invented by combining the free piston engine and the crank connecting rod mechanism of the traditional internal combustion engine. Directly using the reciprocating movement of the piston, this new engine converts the heat energy produced by fuel to electrical energy and output it. The paper expounds the working mechanism of ECPE and establishes the kinematics and dynamics equations. Furthermore, by using the analytic method, the ECPE electromagnetic force is solved at load cases. Finally, in the simulation environment of MARLAB, the universal characteristic curve is obtained in the condition of rotational speed n between 1000 r/min and 2400 r/min, throttle opening α between 30% and 100%.

Mixer pump long term operations plan for Tank 241-SY-101 mitigation

International Nuclear Information System (INIS)

Irwin, J.J.

1994-01-01

This document provides the general Operations Plan for performance of the mixer pump long term operations for Tank 241-SY-101 mitigation of gas retention and periodic release in Tank 101-SY. This operations plan will utilize a 112 kW (150 hp) mixing pump to agitate/suspend the particulates in the tank

Advance in technologies of electric power in 2008

International Nuclear Information System (INIS)

Hamada, Kenichi; Maekawa, Fumiaki; Nakamura, Akio

2008-01-01

Ten electric power companies and two related companies reported their advance in technologies. The technologies of nuclear power plants were stated by ten companies, which consisted of introduction of new main control board to Tomari-3 in Hokkaido Electric Power Co., Inc., reduction methods of exposure dose of Higashidori-1 in Tohoku Electric Power, hot water based two-phase flow testing device for pipe thinning test by Tokyo Electric Power Company, Guideline for prevention of piping damage caused by combustion of mixture gases in BWR (the second edition) published by Thermal and Nuclear Power Engineering Society, setting up distributor in the low-pressure turbine of Shika-2 in Hokuriku Electric Power Company, development of rapid estimation method of release radioactivity and application of high density neutron source to nuclear transmutation of nuclear fuel cycle and introduction of new core monitor system by The Kansai Electric Power Co., Inc., upgrade of investigation of the effects of hot waste water and development of detector for dropout parts of cooling system in reactor by Shikoku Electric Power Co., Inc., change of transformer in Sendai-1 by Kyushu Electric Power Co., Inc., and reactor core design for Oma ABWR by J-Power. The Japan Atomic Power Company reported four articles such as development of technologies for established nuclear power plants, promotion of Tsuruga-3 and Tsuruga-4, application of clearance system in Japan and development of future reactors. (S.Y.)

Engine thermomanagement with electrical components for fuel consumption reduction

Energy Technology Data Exchange (ETDEWEB)

Cortona, E.; Onder, C.H.; Guzzella, L. [Swiss Federal Inst. of Technology, Zurich (Switzerland)

2002-09-01

This paper proposes a solution for advanced temperature control of the relevant temperature of a combustion engine. It analyses the possibility of reducing vehicle fuel consumption by improving engine thermomanagement. In conventional applications, combustion engine cooling systems are designed to guarantee sufficient heat removal at full load. The cooling pump is belt-driven by the combustion engine crankshaft, resulting in a direct coupling of engine and cooling pump speeds. It is dimensioned such that it can guarantee adequate performance over the full engine speed range. This causes an excessive flow of cooling fluid at part-load conditions and at engine cold-start. This negatively affects the engine efficiency and, as a consequence, the overall fuel consumption. Moreover, state-of-the-art cooling systems allow the control of the coolant temperature only by expansion thermostats (solid-to-liquid phase wax actuators). The resulting coolant temperature does not permit engine efficiency to be optimized. In this paper, active control of the coolant flow as well as of the coolant temperature has been realized using an electrical cooling pump and an electrically driven valve which controls the flow distribution between the radiator and its bypass. For this purpose, a control-oriented model of the whole cooling system has been derived. Model-based feedforward and feedback controls of coolant temperature and flow have been designed and tested. With the additional actuators and the model-based control scheme, a good performance in terms of fast heat-up and small temperature overshoot has been achieved. The improvements in fuel consumption obtained with the proposed configuration have been verified on a dynamic testbench. Both engine cold-start under stationary engine operation and the European driving cycle MVEG-A with engine cold-start were tested. The fuel consumption reductions achieved during these tests vary between 2.8 and 4.5 per cent, depending on the engine

SY Tank Farm ventilation isolation option risk assessment report

Energy Technology Data Exchange (ETDEWEB)

Powers, T.B.; Morales, S.D.

1994-03-01

The safety of the 241-SY Tank Farm ventilation system has been under extensive scrutiny due to safety concerns associated with tank 101-SY. Hydrogen and other gases are generated and trapped in the waste below the liquid surface. Periodically, these gases are released into the dome space and vented through the exhaust system. This attention to the ventilation system has resulted in the development of several alternative ventilation system designs. The ventilation system provides the primary means of mitigation of accidents associated with flammable gases. This report provides an assessment of various alternatives ventilation system designs.

Diesel Engine Waste Heat Recovery Utilizing Electric Turbocompound Technology

International Nuclear Information System (INIS)

Gerke, Frank G.

2001-01-01

This cooperative program between the DOE Office of Heavy Vehicle Technology and Caterpillar, Inc. is aimed at demonstrating electric turbocompound technology on a Class 8 truck engine. This is a lab demonstration program, with no provision for on-truck testing of the system. The goal is to demonstrate the level of fuel efficiency improvement attainable with the electric turbocompound system. Also, electric turbocompounding adds an additional level of control to the air supply which could be a component in an emissions control strategy

METHODICS, SOFTWARE AND LABORATORY EQUIPMENT FOR AN INNOVATIVE ELECTRICAL ENGINEERING DISCIPLINE

Directory of Open Access Journals (Sweden)

V.S. Petrushin

2016-09-01

Full Text Available Purpose. Development of innovative electrical engineering discipline «Electric Machines in Mechatronic Systems» in order to improve the training of specialists of electrical engineering specialty. Methodology. The proposed project concerns the educational reforms that promote the intensification of the educational process. Results. The structure of interactive educational and training complex, which is a computer learning tool in the form of software and methodical support, as well as data and knowledge bases and consists of functionally related multimedia learning systems, interactive learning, automated control of the learning process. Originality. To offer online training and research facilities, guidelines for laboratory and computational and graphic works. Practical value. Increase the knowledge of students of educational material related to the discipline of innovation «Electric Machines in Mechatronic Systems».

Linear engine development for series hybrid electric vehicles

Science.gov (United States)

Toth-Nagy, Csaba

This dissertation argues that diminishing oil reserves, concern over global climate change, and desire to improve ambient air quality all demand the development of environment-friendly personal transportation. In certain applications, series hybrid electric vehicles offer an attractive solution to reducing fuel consumption and emissions. Furthermore, linear engines are emerging as a powerplant suited to series HEV applications. In this dissertation, a linear engine/alternator was considered as the auxiliary power unit of a range extender series hybrid electric vehicle. A prototype linear engine/alternator was developed, constructed and tested at West Virginia University. The engine was a 2-stroke, 2-cylinder, dual piston, direct injection, diesel engine. Experiment on the engine was performed to study its behavior. The study variables included mass of the translator, amount of fuel injected, injection timing, load, and stroke with operating frequency and mechanical efficiency as the basis of comparison. The linear engine was analyzed in detail and a simple simulation model was constructed to compare the trends of simulation with the experimental data and to expand on the area where the experimental data were lacking. The simulation was based on a simple and analytical model, rather than a detailed and intensely numerical one. The experimental and theoretical data showed similar trends. Increasing translator mass decreased the operating frequency and increased compression ratio. Larger mass and increased compression ratio improved the ability of the engine to sustain operation and the engine was able to idle on less fuel injected into the cylinder. Increasing the stroke length caused the operating frequency to drop. Increasing fueling or decreasing the load resulted in increased operating frequency. This projects the possibility of using the operating frequency as an input for feedback control of the engine. Injection timing was varied to investigate two different

Process Control Plan for Tank 241-SY-101 Surface Level Rise Remediation

International Nuclear Information System (INIS)

ESTEY, S.D.

1999-01-01

The tank 241-SY-101 transfer system was conceived and designed to address the immediate needs presented by rapidly changing waste conditions in tank 241-SY-101. Within the last year or so, the waste in this tank has exhibited unexpected behavior (Rassat et al. 1999) in the form of rapidly increasing crust growth. This growth has been brought about by a rapidly increasing rate of gas entrapment within the crust. It has been conceived that the lack of crust agitation beginning upon the advent of mixer pump operations may have set-up a more consolidated, gas impermeable barrier when compared to a crust regularly broken up by the prior buoyant displacement events within the tank. As a result, a series of level-growth remediation activities have been developed for tank 241-SY-101. The initial activities are also known as near-term crust mitigation. The first activity of near-term mitigation is to perform the small transfer of convective waste from tank 241-SY-101 into tank 241-SY-102. A 100 kgal transfer represents about a 10% volume reduction allowing a 10% water in-tank dilution. Current thinking holds that this should be enough to dissolve nitrite solids in the crust and perhaps largely eliminate gas retention problem in the crust (Raymond 1999). Additional mitigation activities are also planned on less constrained schedules. The net affect of the small transfer and follow-on mitigation activities for tank 241-SY-101 is strongly believed to be the remediation of tank 241-SY-101 as a flammable gas safety concern. The process for remediating the tank will require two or more transfer/dilution cycles. In-tank dilution will begin shortly after the initial transfer and the total dilution required to reach the final state is estimated to be between 250 to 400K gallons. The final state of the waste will not require any active measures to safely store the waste and operation of the mixer pump will no longer be necessary. The remediation activities are centered on a purpose

Design Review Closure Report for the SY-101 Rapid Transfer System

International Nuclear Information System (INIS)

POWELL, W.J.

1999-01-01

The purpose of this report, is to document closure of design review open items, resulting from design reviews conducted for the SY-101 Respond And Pump In Days (RAPID) Transfer System. Results of the various design reviews were documented in the Design Review Report for The SY-101 Rapid Mitigation System, HNF-4519. In that report, twenty-three open items were identified. In this report the 23 items are reviewed and statused

Design Review Closure Report for the SY-101 Rapid Transfer System

Energy Technology Data Exchange (ETDEWEB)

POWELL, W.J.

1999-11-29

The purpose of this report, is to document closure of design review open items, resulting from design reviews conducted for the SY-101 Respond And Pump In Days (RAPID) Transfer System. Results of the various design reviews were documented in the Design Review Report for The SY-101 Rapid Mitigation System, HNF-4519. In that report, twenty-three open items were identified. In this report the 23 items are reviewed and statused.

Recent advances in electrical engineering and control applications

CERN Document Server

Bououden, Sofiane; Zelinka, Ivan

2017-01-01

This book of proceedings includes papers presenting the state of art in electrical engineering and control theory as well as their applications. The topics focus on classical as well as modern methods for modeling, control, identification and simulation of complex systems with applications in science and engineering. The papers were selected from the hottest topic areas, such as control and systems engineering, renewable energy, faults diagnosis—faults tolerant control, large-scale systems, fractional order systems, unconventional algorithms in control engineering, signals and communications. The control and design of complex systems dynamics, analysis and modeling of its behavior and structure is vitally important in engineering, economics and in science generally science today. Examples of such systems can be seen in the world around us and are a part of our everyday life. Application of modern methods for control, electronics, signal processing and more can be found in our mobile phones, car engines, hom...

KEK Engineering Department -activity report FY 2003

International Nuclear Information System (INIS)

2005-03-01

This report includes all kinds of activities of the Engineering Department of KEK from 2002 to 2003 FY. There are fourteen chapters, which contain KEK Prize for engineering, KEK meeting of engineering technologies, Engineering Seminar, COACK (Component Oriented Advanced Control Kernel) for cooperation R and D project, Forum on engineering technologies from 1998 to 2003 FY, Engineering Department Symposium, service trainings, Engineering Department research study, English training, training for professional worker, training for technical expert, report on joint training for technical expert, training for middle school students, and the Engineering Department system and the main events from 1971 to 2003. (S.Y. )

The record of electrical and communication engineering conversazione Tohoku University Volume 63, No. 3

Science.gov (United States)

1995-05-01

English abstracts contained are from papers authored by the research staff of the Research Institute of Electrical Communication and the departments of Electrical Engineering, Electrical Communications, Electronic Engineering, and Information Engineering, Tohoku University, which originally appeared in scientific journals in 1994. The abstracts are organized under the following disciplines: electromagnetic theory; physics; fundamental theory of information; communication theory and systems; signal and image processing; systems control; computers; artificial intelligence; recording; acoustics and speech; ultrasonic electronics; antenna, propagation, and transmission; optoelectronics and optical communications; quantum electronics; superconducting materials and applications; magnetic materials and magnetics; semiconductors; electronic materials and parts; electronic devices and integrated circuits; electronic circuits; medical electronics and bionics; measurements and applied electronics; electric power; and miscellaneous.

CompTIA Security+ Review Guide Exam SY0-301

CERN Document Server

Stewart, James M

2011-01-01

Reinforce your preparation for CompTIA's new Security+ exam with this focused review tool Before you take CompTIA's new Security+ exam SY0-301, reinforce your learning with a thorough review and lots of practice. The new edition of this concise guide helps you do just that. It covers all six domains of exam SY0-301, all exam objectives, and includes a helpful "Exam Essentials" section after each domain to help you zero in on what you need to know for the exam. A companion CD offers additional study tools, including two complete practice exams, over a hundred electronic flashcards, and more.Rev

Criticality safety analysis of Hanford Waste Tank 241-101-SY

International Nuclear Information System (INIS)

Perry, R.T.; Sapir, J.L.; Krohn, B.J.

1993-01-01

As part of a safety assessment for proposed pump mixing operations to mitigate episodic gas releases in Tank 241-101-SY at the Hanford Site, Richland, Washington, a criticality safety analysis was made using the Sn transport code ONEDANT. The tank contains approximately one million gallons of waste and an estimated 910 G of plutonium. the criticality analysis considers reconfiguration and underestimation of plutonium content. The results indicate that Tank SY-101 does not present a criticality hazard. These methods are also used in criticality analyses of other Hanford tanks

77 FR 76977 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2012-12-31

... Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Supplemental notice... proposed airworthiness directive (AD) for certain General Electric Company (GE) CF6-80C2 series turbofan... part 39 to include an AD that would apply to certain GE CF6-80C2 series turbofan engines. That NPRM...

Nucleo electric conversion; an approximation from physics engineering

International Nuclear Information System (INIS)

Suarez Antola, R.

2009-01-01

The main purpose of this article is carry out some aspects of Civil use in produced Energy conversion from nuclear fi sion in electric energy from one point of view of physical engineering,emphasizing in nuclear power reactors and their fuel oil.

Parallel Hybrid Gas-Electric Geared Turbofan Engine Conceptual Design and Benefits Analysis

Science.gov (United States)

Lents, Charles; Hardin, Larry; Rheaume, Jonathan; Kohlman, Lee

2016-01-01

The conceptual design of a parallel gas-electric hybrid propulsion system for a conventional single aisle twin engine tube and wing vehicle has been developed. The study baseline vehicle and engine technology are discussed, followed by results of the hybrid propulsion system sizing and performance analysis. The weights analysis for the electric energy storage & conversion system and thermal management system is described. Finally, the potential system benefits are assessed.

10th International Conference on Scientific Computing in Electrical Engineering

CERN Document Server

Clemens, Markus; Günther, Michael; Maten, E

2016-01-01

This book is a collection of selected papers presented at the 10th International Conference on Scientific Computing in Electrical Engineering (SCEE), held in Wuppertal, Germany in 2014. The book is divided into five parts, reflecting the main directions of SCEE 2014: 1. Device Modeling, Electric Circuits and Simulation, 2. Computational Electromagnetics, 3. Coupled Problems, 4. Model Order Reduction, and 5. Uncertainty Quantification. Each part starts with a general introduction followed by the actual papers. The aim of the SCEE 2014 conference was to bring together scientists from academia and industry, mathematicians, electrical engineers, computer scientists, and physicists, with the goal of fostering intensive discussions on industrially relevant mathematical problems, with an emphasis on the modeling and numerical simulation of electronic circuits and devices, electromagnetic fields, and coupled problems. The methodological focus was on model order reduction and uncertainty quantification.

Stirling engine electric hybrid vehicle propulsion system conceptual design study. Final report

Energy Technology Data Exchange (ETDEWEB)

Dochat, G; Artiles, A; Killough, J; Ray, A; Chen, H S

1978-08-01

Results of a six-month study to characterize a series Stirling engine electric hybrid vehicle propulsion system are presented. The Stirling engine was selected as the heat conversion element to exploit the high efficiency (> .36), low pollution, multi-fuel and quiet operation of this machine. A free-piston Stirling engine driving a linear alternator in a hermatically sealed enclosure was chosen to gain the reliability, long life, and maintenance free characteristics of a sealed unit. The study performs trade off evaluations, selection of engine, battery, motor and inverter size, optimization of components, and develops a conceptual design and characterization of the total propulsion system. The conclusion of the study is that a Stirling engine electric hybrid propulsion system can be used successfully to augment the battery storage of a passenger vehicle and will result in significant savings of petroleum energy over present passenger vehicles. The performance and range augmentation of the hybrid design results in significant improvements over an all electric vehicle. The hybrid will be capable of performing 99% of the passenger vehicle annual trip distribution requirements with extremely low fuel usage. (TFD)

77 FR 48110 - Airworthiness Directives; General Electric Company Turbofan Engines

Science.gov (United States)

2012-08-13

... Company Turbofan Engines AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed... certain General Electric Company (GE) CF6-80C2 series turbofan engines. The existing AD requires... 2000-04-14, Amendment 39-11597 (65 FR 10698, February 29, 2000), for all GE CF6-80C2 series turbofan...

The Macquarie Dictionary, its History and its Editorial Practices Die Macquarie Dictionary, sy geskiedenis en sy redaksionele praktyke

Directory of Open Access Journals (Sweden)

Arthur Delbridge

2012-09-01

Full Text Available

The Macquarie Dictionary, first published in Sydney in 1981, was intended to be the first comprehensive dictionary of Australian English. Now in its third edition it has been widely adopted by institutions and the general community as the national dictionary. This paper traces its development from a difficult birth to its present maturity, from a large set of cards to an electronic database, from a single book to a lexicographic library. The rationale and the methodology are laid out along with an account of the reception given to the dictionary in Australia and internationally.

Keywords: dictionary; lexicography; macquarie dictionary; australianness; australianise; australian english; national dictionaries; phonology; international phonetic alphabet; lexical labels; lexicographic style; language style; colloquial; aboriginal words; electronic database; corpus; citation

Die Macquarie Dictionary wat vir die eerste keer in 1981 in Sydney gepubliseer is, was bedoel om die eerste omvattende woordeboek van Australiese Engels te wees. Die woordeboek wat tans in sy derde uitgawe is, word reeds algemeen deur instansies en die algemene publiek as nasionale woordeboek aanvaar. Hierdie artikel skets sy ontwikkeling vanaf 'n moeilike geboorte tot sy huidige volwassenheid, vanaf 'n groot versameling kaartjies tot 'n elektroniese databasis, vanaf 'n enkele boek tot 'n leksikografiese biblioteek. Die grondbeginsels en metodologie word gegee saam met 'n verslag van die ontvangs wat dit in Australië en internasionaal gekry het.

Sleutelwoorde: woordeboek; leksikografie; macquarie dictionary; australiesheid; australianiseer; australiese engels; nasionale woordeboeke; fonologie; internasionale fonetiese alfabet; leksikale etikette; leksikografiese styl; taalstyl; omgangstaal; aboriginele woorde; elektroniese databasis; korpus; aanhaling

American Physics and the Origins of Electrical Engineering.

Science.gov (United States)

Rosenberg, Robert

1983-01-01

Traces the development of electrical engineering (EE) from its roots of academic physics in the 1890s to a discipline with its own priorities and departmental structure. Includes a description of the first EE course offered at the Massachusetts Institute of Technology (MIT). (JN)

Reference to the Safety Engineering Undergraduate Courses to Improve the Subjects and Contents of the Certified Safety Engineer Qualification and Examination System of China

OpenAIRE

Haibin Qiu; Shanghong Shi; Tingdi Zhao; Yiwei Qiao; Jiangshi Zhang

2013-01-01

The aim of this paper is to recommend that the subjects and contents of certified safety engineers use safety engineering undergraduate curriculum system for reference. Human resources play an important role in accident prevention and loss control. Education on safety engineering develops quickly in China. Moreover, the State Administration of Work Safety and the National Human Resources and Social Security Ministry have implemented a certified safety engineer qualification and examination sy...

Teaching electronics to first-year non-electrical engineering students

OpenAIRE

Dahnoun, Naim

2017-01-01

Teaching electronics is not only for electrical and electronics students but also for mechanical, aerospace, engineering design, civil and engineering mathematics programmes, which are likely to have electronics units as part of their curriculum. To teach electronics for these non-electronic programmes is very challenging in many aspects. First, the electronics unit has to satisfy the learning outcomes for each programme. Second, the student's motivation is normally very low since electronics...

Electrosprayed Heavy Ion and Nanodrop Beams for Surface Engineering and Electrical Propulsion

Science.gov (United States)

2014-09-10

Studies At the macroscale, the surface of a Taylor cone just before ion emission is an equipotential with a normal electric field strength found from...AFRL-OSR-VA-TR-2014-0246 Electrosprayed Heavy Ion and Nanodrop Beams for Surface Engineering M Gamero-Castano UNIVERSITY OF CALIFORNIA IRVINE Final...298 (Re . 8-98) v Prescribed by ANSI Std. Z39.18 1 Electrosprayed Heavy Ion and Nanodrop Beams for Surface Engineering and Electrical Propulsion

76 FR 68634 - Airworthiness Directives; General Electric Company (GE) CF6 Turbofan Engines

Science.gov (United States)

2011-11-07

... Airworthiness Directives; General Electric Company (GE) CF6 Turbofan Engines AGENCY: Federal Aviation... ``(c) This AD applies to * * * and CF6-80A3 turbofan engines with left-hand links * * *.'' to ``(c) This AD applies to * * * and CF6-80A3 turbofan engines, including engines marked on the engine data...

Dictionary of electrical engineering. Power engineering, automation technology, measurement and control technology, mechatronics. English - German; Fachwoerterbuch Elektrotechnik. Energietechnik, Automatisierungstechnik, Mess-, Steuer- und Regelungstechnik, Mechatronik. Englisch - Deutsch

Energy Technology Data Exchange (ETDEWEB)

Heckler, H.

2007-07-01

The foreign-language vocabulary taught at school usually does not cover terms needed during professional life in electrical engineering. This comprehensive dictionary contains more than 60,000 electrotechnical and engineering terms - used in textbooks, manuals, data sheets, whitepapers and international standards. British English and American English spelling differences are identified. Terms used in IEC standards of the International Electrotechnical Commission are marked, allowing the reader to have easy access to the multilingual glossary of the IEC. This book contains the in-house dictionaries of the internationally operating companies Festo, KEB, Phoenix Contact, and Rittal. Topics: - Basic of electrical engineering, - Electrical power engineering, - Mechatronics, - Electrical drive engineering, - Electrical connection technology, - Automation technology, - Safety-related technology, - Information technology, - Measurement and control technology, - Explosion protection - Power plant technology, - Lightning and overvoltage protection. (orig.)

Structural analysis and evaluation of the 241SY101 tank annulus heat-up

International Nuclear Information System (INIS)

Ziada, H.H.

1994-01-01

This document provides the structural analysis (static and thermal loads) of the 241SY101 tank to determine the maximum allowable temperature and rate of heating that could be applied to tank 241SY101 through annulus air heating without detrimental effects to the structural integrity of the concrete and steel liner of the tank

Electric Utility Transmission and Distribution Line Engineering Program

Energy Technology Data Exchange (ETDEWEB)

Peter McKenny

2010-08-31

Economic development in the United States depends on a reliable and affordable power supply. The nation will need well educated engineers to design a modern, safe, secure, and reliable power grid for our future needs. An anticipated shortage of qualified engineers has caused considerable concern in many professional circles, and various steps are being taken nationwide to alleviate the potential shortage and ensure the North American power system's reliability, and our world-wide economic competitiveness. To help provide a well-educated and trained workforce which can sustain and modernize the nation's power grid, Gonzaga University's School of Engineering and Applied Science has established a five-course (15-credit hour) Certificate Program in Transmission and Distribution (T&D) Engineering. The program has been specifically designed to provide working utility engineering professionals with on-line access to advanced engineering courses which cover modern design practice with an industry-focused theoretical foundation. A total of twelve courses have been developed to-date and students may select any five in their area of interest for the T&D Certificate. As each course is developed and taught by a team of experienced engineers (from public and private utilities, consultants, and industry suppliers), students are provided a unique opportunity to interact directly with different industry experts over the eight weeks of each course. Course material incorporates advanced aspects of civil, electrical, and mechanical engineering disciplines that apply to power system design and are appropriate for graduate engineers. As such, target students for the certificate program include: (1) recent graduates with a Bachelor of Science Degree in an engineering field (civil, mechanical, electrical, etc.); (2) senior engineers moving from other fields to the utility industry (i.e. paper industry to utility engineering or project management positions); and (3) regular

Multiple choice questions in electronics and electrical engineering

CERN Document Server

DAVIES, T J

2013-01-01

A unique compendium of over 2000 multiple choice questions for students of electronics and electrical engineering. This book is designed for the following City and Guilds courses: 2010, 2240, 2320, 2360. It can also be used as a resource for practice questions for any vocational course.

The history of fifty years of institute of electrical engineers 1947-1996

International Nuclear Information System (INIS)

1997-07-01

This book starts with the survey of a century of Korea electrical industry. It includes a business of electric power and electrical machinery industry. Next, it deals with the survey of fifty years of Korea institute electrical engineers. Then, it enumerates the articles of association, organization, board members, the role of the administrative organization, study and institute business activities in detail.

Tank 241-SY-101 push mode core sampling and analysis plan

International Nuclear Information System (INIS)

CONNER, J.M.

1998-01-01

This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for push mode core samples from tank 241-SY-101 (SY-101). It is written in accordance with Data Quality Objective to Support Resolution of the Flammable Gas Safety Issue (Bauer 1998), Low Activity Waste Feed Data Quality Objectives (Wiemers and Miller 1997 and DOE 1998), Data Quality Objectives for TWRS Privatization Phase I: Confirm Tank T is an Appropriate Feed Source for Low-Activity Waste Feed Batch X (Certa 1998), and the Tank Safety Screening Data Quality Objective (Dukelow et al. 1995). The Tank Characterization Technical Sampling Basis document (Brown et al. 1998) indicates that these issues apply to tank SY-101 for this sampling event. Brown et al. also identifies high-level waste, regulatory, pretreatment and disposal issues as applicable issues for this tank. However, these issues will not be addressed via this sampling event

Tank 241-SY-102 January 2000 Compatibility Grab Samples Analytical Results for the Final Report [SEC 1 and 2

Energy Technology Data Exchange (ETDEWEB)

BELL, K.E.

2000-05-11

This document is the format IV, final report for the tank 241-SY-102 (SY-102) grab samples taken in January 2000 to address waste compatibility concerns. Chemical, radiochemical, and physical analyses on the tank SY-102 samples were performed as directed in Comparability Grab Sampling and Analysis Plan for Fiscal Year 2000 (Sasaki 1999). No notification limits were exceeded. Preliminary data on samples 2SY-99-5, -6, and -7 were reported in ''Format II Report on Tank 241-SY-102 Waste Compatibility Grab Samples Taken in January 2000'' (Lockrem 2000). The data presented here represent the final results.

Electrical stimulation directs engineered cardiac tissue to an age-matched native phenotype

Directory of Open Access Journals (Sweden)

Richard A Lasher

2012-12-01

Full Text Available Quantifying structural features of native myocardium in engineered tissue is essential for creating functional tissue that can serve as a surrogate for in vitro testing or the eventual replacement of diseased or injured myocardium. We applied three-dimensional confocal imaging and image analysis to quantitatively describe the features of native and engineered cardiac tissue. Quantitative analysis methods were developed and applied to test the hypothesis that environmental cues direct engineered tissue toward a phenotype resembling that of age-matched native myocardium. The analytical approach was applied to engineered cardiac tissue with and without the application of electrical stimulation as well as to age-matched and adult native tissue. Individual myocytes were segmented from confocal image stacks and assigned a coordinate system from which measures of cell geometry and connexin-43 spatial distribution were calculated. The data were collected from 9 nonstimulated and 12 electrically stimulated engineered tissue constructs and 5 postnatal day 12 and 7 adult hearts. The myocyte volume fraction was nearly double in stimulated engineered tissue compared to nonstimulated engineered tissue (0.34 ± 0.14 vs 0.18 ± 0.06 but less than half of the native postnatal day 12 (0.90 ± 0.06 and adult (0.91 ± 0.04 myocardium. The myocytes under electrical stimulation were more elongated compared to nonstimulated myocytes and exhibited similar lengths, widths, and heights as in age-matched myocardium. Furthermore, the percentage of connexin-43-positive membrane staining was similar in the electrically stimulated, postnatal day 12, and adult myocytes, whereas it was significantly lower in the nonstimulated myocytes. Connexin-43 was found to be primarily located at cell ends for adult myocytes and irregularly but densely clustered over the membranes of nonstimulated, stimulated, and postnatal day 12 myocytes. These findings support our hypothesis and reveal

iSyTE 2.0: a database for expression-based gene discovery in the eye

Science.gov (United States)

Kakrana, Atul; Yang, Andrian; Anand, Deepti; Djordjevic, Djordje; Ramachandruni, Deepti; Singh, Abhyudai; Huang, Hongzhan

2018-01-01

Abstract Although successful in identifying new cataract-linked genes, the previous version of the database iSyTE (integrated Systems Tool for Eye gene discovery) was based on expression information on just three mouse lens stages and was functionally limited to visualization by only UCSC-Genome Browser tracks. To increase its efficacy, here we provide an enhanced iSyTE version 2.0 (URL: http://research.bioinformatics.udel.edu/iSyTE) based on well-curated, comprehensive genome-level lens expression data as a one-stop portal for the effective visualization and analysis of candidate genes in lens development and disease. iSyTE 2.0 includes all publicly available lens Affymetrix and Illumina microarray datasets representing a broad range of embryonic and postnatal stages from wild-type and specific gene-perturbation mouse mutants with eye defects. Further, we developed a new user-friendly web interface for direct access and cogent visualization of the curated expression data, which supports convenient searches and a range of downstream analyses. The utility of these new iSyTE 2.0 features is illustrated through examples of established genes associated with lens development and pathobiology, which serve as tutorials for its application by the end-user. iSyTE 2.0 will facilitate the prioritization of eye development and disease-linked candidate genes in studies involving transcriptomics or next-generation sequencing data, linkage analysis and GWAS approaches. PMID:29036527

Glutathione transferase-M2-2 secreted from glioblastoma cell protects SH-SY5Y cells from aminochrome neurotoxicity.

Science.gov (United States)

Cuevas, Carlos; Huenchuguala, Sandro; Muñoz, Patricia; Villa, Monica; Paris, Irmgard; Mannervik, Bengt; Segura-Aguilar, Juan

2015-04-01

U373MG cells are able to take up aminochrome that induces glutathione transferase M2-2 (GSTM2) expression in a concentration-dependent manner where 100 µM aminochrome increases GSTM2 expression by 2.1-fold (P protects SH-SY5Y cells incubated with 10 µM aminochrome. The significant protection provided by U373MG-conditioned medium in SH-SY5Y cells incubated with aminochrome was dependent on GSTM2 internalization into SH-SY5Y cells as evidenced by (i) uptake of (14)C-GSTM2 released from U373MG cells into SH-SY5Y cells, a process inhibited by anti-GSTM2 antiserum; (ii) lack of protection of U373MG-conditioned medium in the presence of anti-GSTM2 antiserum on SH-SY5Y cells treated with aminochrome; and (iii) lack of protection of conditioned medium from U373MGsiGST6 that expresses an siRNA directed against GSTM2 on SH-SY5Y cells treated with aminochrome. In conclusion, our results demonstrated that U373MG cells protect SH-SY5Y cells against aminochrome neurotoxicity by releasing GSTM2 into the conditioned medium and subsequent internalization of GSTM2 into SH-SY5Y cells. These results suggest a new mechanism of protection of dopaminergic neurons mediated by astrocytes by releasing GSTM2 into the intersynaptic space and subsequent internalization into dopaminergic neuron in order to protect these cells against aminochrome neurotoxicity.

Tietoa terveydestä ja miesten yleisimmistä syövistä : Miehen katsastuskortti

OpenAIRE

Haverila, Erika; Karppinen, Tiina

2017-01-01

Suomessa todetaan yli 27 000 syöpää vuodessa ja siihen kuolee yli 10 000 ihmistä. Syövät ovat yleistyneet väestössä ja yleistyvät jatkossakin, koska ikääntyneiden määrä lisääntyy. Syövän riskitekijöitä ovat ikä, periytyvyys, ympäristötekijät sekä elintavat. Elintavoista tupak-ointi, epäterveellinen ravitsemus, alkoholin liikakäyttö, liian vähäinen liikunta, ylipaino sekä liian runsas altistuminen auringonvalolle ovat tärkeimpiä riskitekijöitä. Terveyden edi-stämistä voidaan pitää yksilön pros...

Modeling the dynamic and thermodynamic operation of Stirling engines by means of an equivalent electrical circuit

International Nuclear Information System (INIS)

Cascella, Franco; Sorin, Mikhail; Formosa, Fabien; Teyssedou, Alberto

2017-01-01

Highlights: • A model based on the electrical analogy theory has been developed to predict the operation of a Stirling engine. • The models takes into account the continuity, the momentum and the energy conservation equations. • The model predicts the operating conditions of the RE100 Free piston Stirling engine. • The model is sensible to the modeling of the effects of the machine load. - Abstract: The Stirling engines are inherently efficient; their thermodynamic cycles reach the Carnot efficiency. These technologies are suitable to operate under any low temperature difference between the hot and the cold sources. For these reasons, these engines can be considered as reliable power conversion systems to promote the conversion of low-grade waste heat generated by industrial plants. The need of a model to predict the behavior of these engines is of primary importance. Nevertheless, a great difficulty is encountered in developing such a model since it is not simple to take into account coupled thermodynamic and dynamic effects. This is the main reason why several models make use of electrical analogies to describe Stirling engines (in particular, free-piston machines): by assuming the pressure equivalent to a voltage and the flow rate to an electrical current, a coupled dynamic-thermodynamic analysis of the engine can be performed. In this paper, an electrical circuit whose behavior is equivalent to that of the engine is derived from the electrical analogy theory. To this aim, we propose an electrical analogy model based on the three conservation laws (mass, momentum and energy). Since limited experimental information is available in the open literature, the results obtained with the proposed model are compared with the experimental data collected at the NASA Lewis Research center for a free-piston Stirling engine i.e., the RE-1000 engine.

Photonics education development for electrical engineering students

Science.gov (United States)

Cao, Yang; Luo, Yuan; Liu, Yu; Hu, ZhangFang; Cai, Xuemei

2017-08-01

We describe the contents of an advanced undergraduate course on photonics at School of Electrical Engineering, Chongqing University of Posts and Telecommunications. The main goal of the course is to equip the student with the necessary theoretical and practical knowledge to participate in photonics-related industry and further graduate level study and research if they choose. The prerequisites include college-level physics and higher mathematics which a general engineering student has already had in his/her first and second year college study. Although applications of photonics are ubiquitous such as telecommunications, photonic computing, spectroscopy, military technology, and biophotonics etc. Telecommunication information system application is more emphasized in our course considering about the potential job chances for our students.

Engineering electrical properties of graphene: chemical approaches

International Nuclear Information System (INIS)

Kim, Yong-Jin; Kim, Yuna; Hong, Byung Hee; Novoselov, Konstantin

2015-01-01

To ensure the high performance of graphene-based devices, it is necessary to engineer the electrical properties of graphene with enhanced conductivity, controlled work function, opened or closed bandgaps, etc. This can be performed by various non-covalent chemical approaches, including molecular adsorption, substrate-induced doping, polymerization on graphene, deposition of metallic thin films or nanoparticles, etc. In addition, covalent approaches such as the substitution of carbon atoms with boron or nitrogen and the functionalization with hydrogen or fluorine are useful to tune the bandgaps more efficiently, with better uniformity and stability. In this review, representative examples of chemically engineered graphene and its device applications will be reviewed, and remaining challenges will be discussed. (topical review)

Perception of Leadership in Electrical Engineering Students, UTHM

Science.gov (United States)

Saari, Farrah Atikah Binti; Ghani, Nor Aslasiah Binti

2015-01-01

Demand for graduates with leadership skills more in priority to meet the needs of human resources. Hence, this study was undertaken to investigate the level of leadership skills among students in Electrical Engineering at University Tun Hussein Onn Malaysia. Descriptive study carried out to evaluate student leadership. The study sample consisted…

Electrical engineering research support for FDOT Traffic Statistics Office

Science.gov (United States)

2010-03-01

The aim of this project was to provide electrical engineering support for the telemetered traffic monitoring sites (TTMSs) operated by the Statistics Office of the Florida Department of Transportation. This project was a continuation of project BD-54...

Ontsporing van die regstaatsbegrip en sy konsekwensies vir die afrikanervolk

Directory of Open Access Journals (Sweden)

N. G.S. Van der Walt

1966-03-01

Full Text Available Die opvatting van die suiwere regstaat bring sy vraagstukke mee wanneer dit in verband gebring word met die leer van die soewereiniteit in eie kring. Laasgenoemde leer wortel in die geloof dat God die mens roep tot diens aan Hom, en dat die mens vry moet wees om ten opsigte van alle lewensaspekte God na die hoogste mate te kan dien. Hierdie verskeidenheid van aspekte is deur dr. A. Kuyper en sy volgelinge gesistemati- seer tot menslike verbande en lewenskringe, elk met ’n be- paalde sfeer waarin ander kringe nie mag inmeng nie. Elkeen is dan soewerein binne sy eie kring. Met verwysing na die staat is dan gespreek van die staatstaak as synde die hand- hawing van die reg, en omdat die staat in toenemende mate hom veral in die latere tyd ook besig gehou het met bedrywig- hede wat nouliks as van juridiese aard beskou kan word, is daar die onderskeid gemaak tussen die primêre en sekundêre taak van die staat. Die sistematiek van die wetsidee, deur prof. Dooyeweerd ontwikkel, waar die staat sy bestemmingsfunksie in die regsaspek vind, het vanselfsprekend geen plek vir so 'n dualistiese staatstaak nie, en die oplossing is deur sommige daarin gesoek om sulke staatsoptrede te vertolk as hebbende wel betrekking op die regsgemeenskap of die regsverkeer. Staatsondernemings soos paaie, spoorweë, spellingreëling, ens. word dan beskou as noodsaaklik vir die instandhouding van die regsgemeenskap en regsverkeer. Tereg wys A. M. Donner1 daarop dat so ’n vertolking eintlik neerkom op ’n oorspanning van die regsbegrip. Hy self sien dan die staatstaak in vrede- of orde-handhawing, wat in die eerste plaas wel regshandha- wing veronderstel. Onder orde word dan alles verstaan wat noodsaaklik is vir die gladde verkeer in die ontwikkelingsgang van die regsgemeenskap. Die wese van die staat het dan vol- gens hom te doen met reg, maar sy taak is meer as suiwere regshandhawing. Wat onrus verwek en die orde versteur, moet uit die openbare lewe verwyder word, en die

Research Capabilities Directed to all Electric Engineering Teachers, from an Alternative Energy Model

Directory of Open Access Journals (Sweden)

Víctor Hugo Ordóñez Navea

2017-08-01

Full Text Available The purpose of this work was to contemplate research capabilities directed to all electric engineering teachers from an alternative energy model intro the explanation of a semiconductor in the National Training Program in Electricity. Some authors, such as. Vidal (2016, Atencio (2014 y Camilo (2012 point out to technological applications with semiconductor electrical devices. In this way; a diagnostic phase is presented, held on this field research as a descriptive type about: a how to identify the necessities of alternative energies, and b The research competences in the alternatives energies of researcher from a solar cell model, to boost and innovate the academic praxis and technologic ingenuity. Themselves was applied a survey for a group of 15 teachers in the National Program of Formation in electricity to diagnose the deficiencies in the research area of alternatives energies. The process of data analysis was carried out through descriptive statistic. Later the conclusions are presented the need to generate strategies for stimulate and propose exploration of alternatives energies to the development of research competences directed to the teachers of electrical engineering for develop the research competences in the enforcement of the teachers exercise for the electric engineering, from an alternative energy model and boost the technologic research in the renewal energies field.

International symposium on Electron-magnetic fields in mechatronics, electrical and electronique engineering

CERN Document Server

Krawczyk, Andrzej; Dolezel, Ivo

2008-01-01

Includes contributions on electromagnetic fields in electrical engineering which intends at joining theory and practice. This book helps the world-wide electromagnetic community, both academic and engineering, in understanding electromagnetism itself and its application to technical problems.

101-SY waste sample speed of sound/rheology testing for sonic probe program

International Nuclear Information System (INIS)

Cannon, N.S.

1994-01-01

One problem faced in the clean-up operation at Hanford is that a number of radioactive waste storage tanks are experiencing a periodic buildup and release of potentially explosive gases. The best known example is Tank 241-SY-101 (commonly referred to as 101-SY) in which hydrogen gas periodically built up within the waste to the point that increased buoyancy caused a roll-over event, in which the gas was suddenly released in potentially explosive concentrations (if an ignition source were present). The sonic probe concept is to generate acoustic vibrations in the 101-SY tank waste at nominally 100 Hz, with sufficient amplitude to cause the controlled release of hydrogen bubbles trapped in the waste. The sonic probe may provide a potentially cost-effective alternative to large mixer pumps now used for hydrogen mitigation purposes. Two important parameters needed to determine sonic probe effectiveness and design are the speed of sound and yield stress of the tank waste. Tests to determine these parameters in a 240 ml sample of 101-SY waste (obtained near the tank bottom) were performed, and the results are reported

Scenario Based E-Learning in Electrical Engineering Education

Science.gov (United States)

Tambunan, Hamonangan; Dalimunte, Amirhud; Silitonga, Marsangkap

2017-01-01

The scenario based e-learning in Electrical Engineering Education Learning (EEEL) was developed by covering the scope and characteristics of all subjects and the competence unit of graduates in the field of pedagogy, professional, social and personality, with url addresed http://jpte-ft-unimed.edu20.org. The scenario incorporates the concept of…

An Interactive Computer Aided Electrical Engineering Education Package.

Science.gov (United States)

Cavati, Cicero Romao

This paper describes an educational package to help the learning process. A case study is presented of an energy distribution course in the Electrical Engineering Department at the Federal University of Espirito Santo (UFES). The advantages of the developed package are shown by comparing it with the traditional academic book. This package presents…

Autophagy regulates chlorpyrifos-induced apoptosis in SH-SY5Y cells

International Nuclear Information System (INIS)

Park, Jae Hyeon; Lee, Jeong Eun; Shin, In Chul; Koh, Hyun Chul

2013-01-01

Recent studies have shown that up-regulation of autophagy may be a tractable therapeutic intervention for clearing disease-causing proteins, including α-synuclein, ubiquitin, and other misfolded or aggregated proteins in pesticide-induced neurodegeneration. In a previous study, we reported that chlorpyrifos (CPF)-induced mitochondria-dependent apoptosis is mediated through reactive oxygen species in SH-SY5Y cells. In this study, we explored a novel pharmacotherapeutic approach to prevent CPF neurotoxicity involving the regulation of autophagy. We investigated the modulation of CPF-induced apoptosis according to autophagy regulation. We found that CPF induced apoptosis in SH-SY5Y cells, as demonstrated by the activation of caspase-3 and nuclear condensation. In addition, we observed that cells treated with CPF underwent autophagic cell death by monitoring the expression of LC3-II and p62. Pretreatment with the autophagy inducer rapamycin significantly enhanced the cell viability of CPF-exposed cells, and the enhancement of cell viability was partially due to alleviation of CPF-induced apoptosis via a decrease in levels of cleaved caspase-3. Specifically, rapamycin pretreatment decreased Bax and increased Bcl-2 expression in mitochondria. In addition, rapamycin significantly decreased cytochrome c release in from mitochondria into the cytosol. However, pretreatment of cells with the autophagy inhibitor, 3-methyladenine (3MA), remarkably increased CPF toxicity in these cells; this with correlated with increased expression of Bax and decreased expression of Bcl-2 in mitochondria. Our results suggest that CPF-induced cytotoxicity is modified by autophagy regulation and that rapamycin protects against CPF-induced apoptosis by enhancing autophagy. Pharmacologic induction of autophagy by rapamycin may be a useful treatment strategy in neurodegenerative disorders. - Highlights: ► Chlorpyrifos (CPF) is cytotoxic to SH-SY5Y cells ► CPF-induced cytotoxicity is mediated by

Autophagy regulates chlorpyrifos-induced apoptosis in SH-SY5Y cells

Energy Technology Data Exchange (ETDEWEB)

Park, Jae Hyeon [Department of Pharmacology, College of Medicine, Hanyang University (Korea, Republic of); Hanyang Biomedical Research Institute, Seoul (Korea, Republic of); Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul (Korea, Republic of); Lee, Jeong Eun [Department of Pharmacology, College of Medicine, Hanyang University (Korea, Republic of); Hanyang Biomedical Research Institute, Seoul (Korea, Republic of); Shin, In Chul [Department of Pharmacology, College of Medicine, Hanyang University (Korea, Republic of); Koh, Hyun Chul, E-mail: hckoh@hanyang.ac.kr [Department of Pharmacology, College of Medicine, Hanyang University (Korea, Republic of); Hanyang Biomedical Research Institute, Seoul (Korea, Republic of); Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul (Korea, Republic of)

2013-04-01

Recent studies have shown that up-regulation of autophagy may be a tractable therapeutic intervention for clearing disease-causing proteins, including α-synuclein, ubiquitin, and other misfolded or aggregated proteins in pesticide-induced neurodegeneration. In a previous study, we reported that chlorpyrifos (CPF)-induced mitochondria-dependent apoptosis is mediated through reactive oxygen species in SH-SY5Y cells. In this study, we explored a novel pharmacotherapeutic approach to prevent CPF neurotoxicity involving the regulation of autophagy. We investigated the modulation of CPF-induced apoptosis according to autophagy regulation. We found that CPF induced apoptosis in SH-SY5Y cells, as demonstrated by the activation of caspase-3 and nuclear condensation. In addition, we observed that cells treated with CPF underwent autophagic cell death by monitoring the expression of LC3-II and p62. Pretreatment with the autophagy inducer rapamycin significantly enhanced the cell viability of CPF-exposed cells, and the enhancement of cell viability was partially due to alleviation of CPF-induced apoptosis via a decrease in levels of cleaved caspase-3. Specifically, rapamycin pretreatment decreased Bax and increased Bcl-2 expression in mitochondria. In addition, rapamycin significantly decreased cytochrome c release in from mitochondria into the cytosol. However, pretreatment of cells with the autophagy inhibitor, 3-methyladenine (3MA), remarkably increased CPF toxicity in these cells; this with correlated with increased expression of Bax and decreased expression of Bcl-2 in mitochondria. Our results suggest that CPF-induced cytotoxicity is modified by autophagy regulation and that rapamycin protects against CPF-induced apoptosis by enhancing autophagy. Pharmacologic induction of autophagy by rapamycin may be a useful treatment strategy in neurodegenerative disorders. - Highlights: ► Chlorpyrifos (CPF) is cytotoxic to SH-SY5Y cells ► CPF-induced cytotoxicity is mediated by

An assessment of the dilution required to mitigate Hanford tank 241-SY-101

International Nuclear Information System (INIS)

Hudson, J.D.; Bredt, P.R.; Felmy, A.R.; Stewart, C.W.; Tingey, J.M.; Trent, D.S.; Barney, G.S.; Herting, D.L.; Larrick, A.P.; Reynolds, D.A.

1995-02-01

A group of experts from PNL and WHC convened November 2 and 3, 1994, to screen the current state of knowledge about dilution and reach a consensus on the minimum dilution ratio that will achieve passive mitigation of Tank 241-SY-101 wastes and the dilution ratio that would satisfy the given cross-site transfer criteria with reasonable assurance. The panel evaluated the effects of dilution on the parameters important in gas generation, retention, and release and reached the following conclusions, which are deduced from the existing body of data, experience, and analyses: (1) Dissolution of solids is the single most important aspect of mitigation by dilution. We are confident that diluting until nitrates, nitrites, and aluminum salts are dissolved will mitigate Hanford flammable gas tanks; (2) Sufficient solids dissolution can be achieved in Tank 241-SY-101 at a dilution ratio of 1:1, which will result in a average specific gravity of approximately 1.35. It is likely that a 0.5:1 dilution will also mitigate 241-SY-101, but the current uncertainty is too high to recommend this dilution ratio; (3) The recommended dilution requires a diluent with at least 2 molar free hydroxide, because aluminum probably precipitates at lower hydroxide concentrations. The transfer criteria for Tank 241-SY-101 waste were also evaluated. These criteria have been specified as solids content ≤30% (volume), viscosity ≤30% cP and density <1.5 g/mL. (1) Solids content is the limiting criterion if it is defined as volume fraction of settled solids. A 1:1 dilution will satisfy this criterion at nominal premixing conditions in Tank 241-SY-101; however, analysis of Window E core samples suggests that up to 1.5:1 might be required. If the solids content is interpreted simply as solids volume fraction no further dilution is necessary, because Tank 241-SY-101 waste (excluding the crust) is already below 30%; (2) Bulk density is the next limiting criterion and is met at 0.4:1 dilution

Electrical Power Grid Delivery Dynamic Analysis: Using Prime Mover Engines to Balance Dynamic Wind Turbine Output

Energy Technology Data Exchange (ETDEWEB)

Diana K. Grauer; Michael E. Reed

2011-11-01

This paper presents an investigation into integrated wind + combustion engine high penetration electrical generation systems. Renewable generation systems are now a reality of electrical transmission. Unfortunately, many of these renewable energy supplies are stochastic and highly dynamic. Conversely, the existing national grid has been designed for steady state operation. The research team has developed an algorithm to investigate the feasibility and relative capability of a reciprocating internal combustion engine to directly integrate with wind generation in a tightly coupled Hybrid Energy System. Utilizing the Idaho National Laboratory developed Phoenix Model Integration Platform, the research team has coupled demand data with wind turbine generation data and the Aspen Custom Modeler reciprocating engine electrical generator model to investigate the capability of reciprocating engine electrical generation to balance stochastic renewable energy.

241-SY-101 mixer pump lifetime expectancy. Final report

International Nuclear Information System (INIS)

Shaw, C.P.

1995-01-01

The purpose of WHC-SD-WM-TI-726, Rev. 0 241-SY-101 Mixer Pump Lifetime Expectancy is to determine a best estimate of the mean lifetime of non-repairable (located in the waste) essential features of the hydrogen mitigation mixer pump presently installed in 101-SY. The estimated mean lifetime is 9.1 years. This report does not demonstrate operation of the entire pump assembly within the Tank Farm ''safety envelope''. It was recognized by the Defense Nuclear Facilities Safety Board (DNFSB) this test pump was not specifically designed for long term service in tank 101-SY. In June 95 the DNFSB visited Hanford and ask the question, ''how long will this test pump last and how will the essential features fail?'' During the 2 day meeting with the DNFSB it was discussed and defined within the meeting just exactly what essential features of the pump must operate. These essential features would allow the pump to operate for the purpose of extending the window for replacement. Operating with only essential features would definitely be outside the operating safety envelope and would require a waiver. There are three essential features: 1. The pump itself (i.e. the impeller and motor) must operate 2. Nozzles and discharges leg must remain unplugged 3. The pump can be re-aimed, new waste targeted, even if manually

Syed Manzoorul Islam's Postmodern Tales: A Study

Science.gov (United States)

Sarker, Md Abdul Momen; Talukder, Tusar

2016-01-01

The paper brings into focus how Syed Manzoorul Islam, in his three-decade-long literary career, has mastered a narrative style that sets him apart from many of his Bengali contemporaries. It demonstrates all the traits unique to his storytelling: blurring of boundaries between dream and reality, self-reflexivity, irony, and humor. The research…

Modification and tuning of diesel bus engine for biogas electricity production

Directory of Open Access Journals (Sweden)

Sittiboon Siripornakarachai

2007-11-01

Full Text Available This study is to convert and tune a bus diesel engine for electricity production in a farm using biogas as fuel. The engine under study is a Hino K-13CTI 13,000 cc 24 valve turbocharged engine coupled to a 3 phase 4 pole induction motor to produce electricity at 50 Hz. Modifications include an addition of biogas carburetor for air-fuel mixing, replacing the fuel injection system with spark ignition system, reduction of compression ratio from the original 16:1 to 8:1 using a cylinder head spacer, and modification of the turbocharger waste gate so the boost pressure can be adjusted. When the induction motor is synchronized to the power grid, the running speed of the engine is 1,500 rpm. Optimal engine efficiency was achieved at 28.6% by setting the lambda factor at 1.097, ignition timing at 54o before top dead center, and the turbocharger boost at 56 kPa. With this setting, the generator power output is 134.20 kilowatt with emission of CO and NOX being 1,154 and 896 ppm respectively.

241-SY-101 data acquisition and control system (DACS) remote operator interface operational test report

International Nuclear Information System (INIS)

ERMI, A.M.

1999-01-01

The readiness of the upgraded 241-SY-101 Data Acquisition and Control System (DACS) to provide proper control and monitoring of the mixer pump and instrumentation in tank 241-SY-101 was evaluated by the performance of OTP-440-001. Results of the OTP are reported here

Elementary mathematical and computational tools for electrical and computer engineers using Matlab

CERN Document Server

Manassah, Jamal T

2013-01-01

Ideal for use as a short-course textbook and for self-study Elementary Mathematical and Computational Tools for Electrical and Computer Engineers Using MATLAB fills that gap. Accessible after just one semester of calculus, it introduces the many practical analytical and numerical tools that are essential to success both in future studies and in professional life. Sharply focused on the needs of the electrical and computer engineering communities, the text provides a wealth of relevant exercises and design problems. Changes in MATLAB's version 6.0 are included in a special addendum.

Tank 241-SY-103 tank characterization plan. Revision 1

International Nuclear Information System (INIS)

Homi, C.S.

1995-01-01

This document is a plan that identifies the information needed to address relevant issues concerning short-term and long-term safe storage and long-term management of Single-Shell Tank (SST) 241-SY-103

Paracrine Maturation and Migration of SH-SY5Y Cells by Dental Pulp Stem Cells.

Science.gov (United States)

Gervois, P; Wolfs, E; Dillen, Y; Hilkens, P; Ratajczak, J; Driesen, R B; Vangansewinkel, T; Bronckaers, A; Brône, B; Struys, T; Lambrichts, I

2017-06-01

Neurological disorders are characterized by neurodegeneration and/or loss of neuronal function, which cannot be adequately repaired by the host. Therefore, there is need for novel treatment options such as cell-based therapies that aim to salvage or reconstitute the lost tissue or that stimulate host repair. The present study aimed to evaluate the paracrine effects of human dental pulp stem cells (hDPSCs) on the migration and neural maturation of human SH-SY5Y neuroblastoma cells. The hDPSC secretome had a significant chemoattractive effect on SH-SY5Y cells as shown by a transwell assay. To evaluate neural maturation, SH-SY5Y cells were first induced toward neuronal cells, after which they were exposed to the hDPSC secretome. In addition, SH-SY5Y cells subjected to the hDPSC secretome showed increased neuritogenesis compared with nonexposed cells. Maturated cells were shown to increase immune reactivity for neuronal markers compared with controls. Ultrastructurally, retinoic acid (RA) signaling and subsequent exposure to the hDPSC secretome induced a gradual rise in metabolic activity and neuronal features such as multivesicular bodies and cytoskeletal elements associated with cellular communication. In addition, electrophysiological recordings of differentiating cells demonstrated a transition toward a neuronal electrophysiological profile based on the maximum tetrodotoxin (TTX)-sensitive, Na + current. Moreover, conditioned medium (CM)-hDPSC-maturated SH-SY5Y cells developed distinct features including, Cd 2+ -sensitive currents, which suggests that CM-hDPSC-maturated SH-SY5Y acquired voltage-gated Ca 2+ channels. The results reported in this study demonstrate the potential of hDPSCs to support differentiation and recruitment of cells with neuronal precursor characteristics in a paracrine manner. Moreover, this in vitro experimental design showed that the widely used SH-SY5Y cell line can improve and simplify the preclinical in vitro research on the molecular

Electrical engineering yearbook 1994. 13. ed. Jahrbuch Elektrotechnik '94; Daten, Fakten, Trends

Energy Technology Data Exchange (ETDEWEB)

Gruetz, A. (ed.)

1993-01-01

The book gives a current view of the wide field of electrical engineering and electronics. Contents: Fuzzing logic; neural networks; data systems; electromagnetic radiation; electric motors of advanced technology; DIN VDE 0100; construction regulations for power transmission systems. The appendix contains the VDE guide, statistical data of the German electric power industry and electricity supply industry, technical units, and a calendar. (orig.)

Level maintenance for Tank 101-SY mitigation-by-mixing test. Revision 2

International Nuclear Information System (INIS)

Larsen, D.C.

1994-01-01

The Phase A, Phase B and Full Scale testing portions of the Mitigation-By-Mixing Test have demonstrated the effectiveness of the Mixer Pump to maintain the waste in tank 101-SY in the desired mitigated state. The operation of the 101-SY Mixer Pump for short periods of time results in a controlled release of hydrogen gas in concentrations well below the established safety limits. Additionally, it has been shown that operation of the pump on a regular schedule minimizes the historical generation rate of hydrogen inventory in the waste. Generation of hydrogen inventory is exhibited by waste level growth. The primary objective of this procedure is to maintain the waste level in tank 241-SY-101 within the safe operating range as defined by the Safety Assessment and the Test Plan. The secondary objective is to operate the pump on a schedule that maximizes its useful lifespan and prevents the formation of obstructions in the normal flow path of the pump

A survey of available information on gas generation in tank 241-SY-101: Hanford Tank Safety Project

International Nuclear Information System (INIS)

Strachan, D.M.; Reynolds, D.A.; Siemer, D.D.; Wallace, R.W.

1991-03-01

As a result of a concerted effort to determine the chemical and physical mechanisms underlying the generation and episodic release of gases from tank 241-SY-101, more commonly known as tank 101-SY, the Tank Waste Science Panel has been established at the Pacific Northwest Laboratory. Four of the members of this panel met to screen the available information on tank 101-SY and provide to the remaining members a shortened list of references that could be used to assess the mechanisms underlying the generation and episodic release of gases from tank 101-SY. This document is the result of this preliminary screening of information for the Tank Waste Science Panel and was provided to the Panel members at their first meeting. 14 refs., 3 tabs

Hysterosalpingo-foam sonography (HyFoSy): Tolerability, safety and the occurrence of pregnancy post-procedure.

Science.gov (United States)

Tanaka, Keisuke; Chua, Jackie; Cincotta, Robert; Ballard, Emma L; Duncombe, Gregory

2018-02-01

Fallopian tube patency testing is an essential part of infertility evaluation. Hysterosalpingo-contrast sonography (HyCoSy) has been described as reliable, well tolerated and safe compared to other modalities such as laparoscopy and a dye test or hysterosalpingography. Limited availability of the previously used contrast has led to the introduction of a foam contrast agent as an alternative. To assess the tolerability, safety and occurrence of pregnancy post-procedure of hysterosalpingo-foam sonography (HyFoSy). A retrospective cohort study of women who had a HyFoSy at Queensland Ultrasound for Women from March 2013 to February 2015. A questionnaire was sent to their referring doctor to identify any complications or subsequent pregnancies with or without artificial reproductive technology (ART) within six months of the HyFoSy. Of 200 women, four cases were abandoned due to difficulty introducing the intracervical catheter, severe discomfort or a vasovagal episode. Response from referring doctors for 155 women reported no post-procedural complication. One hundred and eleven women were followed up for at least six months. Twenty-four out of 59 women (40.7%) who had ART and 24 out of 52 women (46.2%) who did not have ART conceived. Fifty percent of women who were nulligravida at the time of investigation, found to have at least one patent fallopian tube, whose partner had a normal semen analysis, spontaneously conceived within the time of follow up. HyFoSy is well tolerated and safe. A preponderance of pregnancies in the first month after HyFoSy suggests that a therapeutic effect may exist. © 2017 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

Operability test procedure [Tank] 241-SY-101 equipment removal system

International Nuclear Information System (INIS)

Mast, J.C.

1994-01-01

The 241-SY-101 equipment removal system (ERS) consists of components, equipment, instrumentation and procedures that will provide the means to disconnect, retrieve, contain, load and transport the Mitigation Pump Assembly (MPA) from waste Tank 241-SY-101 to the Central Waste Complex (CWC). The Operability Test Procedure (OTP) will test the interfaces between ERS components and will rehearse the procedure for MPA removal and transportation to the extent they can be mocked-up at the CTF (Cold Test Facility). At the conclusion of the OTP, the ERS components and equipment will be removed from the CTF, entered into the Component Based Recall System (CBRS), and stored until needed for actual MPA removal and transportation

A Discussion of SY-101 Crust Gas Retention and Release Mechanisms

International Nuclear Information System (INIS)

Mendoza, D.P.; Mahoney, L.A.; Gauglitz, P.A.; Rassat, S.D.; Caley, S.M.

1999-01-01

The flammable gas hazard in Hanford waste tanks was made an issue by the behavior of double-shell Tank (DST) 241-SY-101 (SY-101). Shortly after SY-101 was filled in 1980, the waste level began rising periodically, due to the generation and retention of gases within the slurry, and then suddenly dropping as the gases were released. An intensive study of the tank's behavior revealed that these episodic releases posed a safety hazard because the released gas was flammable, and, in some cases, the volume of gas released was sufficient to exceed the lower flammability limit (LFL) in the tank headspace (Alleinann et al. 1993). A mixer pump was installed in SY-101 in late 1993 to prevent gases from building up in the settled solids layer, and the large episodic gas releases have since ceased (Allemann et al. 1994; Stewart et al. 1994; Brewster et al. 1995). However, the surface level of SY-101 has been increasing since at least 1995, and in recent months the level growth has shown significant and unexpected acceleration. Based on a number of observations and measurements, including data from the void fraction instrument (VFI), we have concluded that the level growth is caused largely by increased gas retention in the floating crust. In September 1998, the crust contained between about 21 and 43% void based on VFI measurements (Stewart et al. 1998). Accordingly, it is important to understand the dominant mechanisms of gas retention, why the gas retention is increasing, and whether the accelerating level increase will continue, diminish or even reverse. It is expected that the retained gas in the crust is flammable, with hydrogen as a major constituent. This gas inventory would pose a flammable gas hazard if it were to release suddenly. In May 1997, the mechanisms of bubble retention and release from crust material were the subject of a workshop. The evaluation of the crust and potential hazards assumed a more typical void of roughly 15% gas. It could be similar to

A Discussion of SY-101 Crust Gas Retention and Release Mechanisms

Energy Technology Data Exchange (ETDEWEB)

SD Rassat; PA Gauglitz; SM Caley; LA Mahoney; DP Mendoza

1999-02-23

The flammable gas hazard in Hanford waste tanks was made an issue by the behavior of double-shell Tank (DST) 241-SY-101 (SY-101). Shortly after SY-101 was filled in 1980, the waste level began rising periodically, due to the generation and retention of gases within the slurry, and then suddenly dropping as the gases were released. An intensive study of the tank's behavior revealed that these episodic releases posed a safety hazard because the released gas was flammable, and, in some cases, the volume of gas released was sufficient to exceed the lower flammability limit (LFL) in the tank headspace (Allemann et al. 1993). A mixer pump was installed in SY-101 in late 1993 to prevent gases from building up in the settled solids layer, and the large episodic gas releases have since ceased (Allemann et al. 1994; Stewart et al. 1994; Brewster et al. 1995). However, the surface level of SY-101 has been increasing since at least 1995, and in recent months the level growth has shown significant and unexpected acceleration. Based on a number of observations and measurements, including data from the void fraction instrument (VFI), we have concluded that the level growth is caused largely by increased gas retention in the floating crust. In September 1998, the crust contained between about 21 and 43% void based on VFI measurements (Stewart et al. 1998). Accordingly, it is important to understand the dominant mechanisms of gas retention, why the gas retention is increasing, and whether the accelerating level increase will continue, diminish or even reverse. It is expected that the retained gas in the crust is flammable, with hydrogen as a major constituent. This gas inventory would pose a flammable gas hazard if it were to release suddenly. In May 1997, the mechanisms of bubble retention and release from crust material were the subject of a workshop. The evaluation of the crust and potential hazards assumed a more typical void of roughly 15% gas. It could be similar to

Design analysis supporting 101-SY Water Decon System

International Nuclear Information System (INIS)

Cleveland, K.J.

1995-01-01

This document contains the results of stress analysis and component sizing for the 101-SY mitigation pump, Water Decon System. Calculations included are a stress analysis of the High Pressure Manifold, the threaded connection on the Yoke Water Connector and a sizing of an air receiver tank

IEEE [Institute of Electrical and Electronics Engineers] standards and nuclear software quality engineering

International Nuclear Information System (INIS)

Daughtrey, T.

1988-01-01

Significant new nuclear-specific software standards have recently been adopted under the sponsorship of the American Nuclear Society and the American Society of Mechanical Engineers. The interest of the US Nuclear Regulatory Commission has also been expressed through their issuance of NUREG/CR-4640. These efforts all indicate a growing awareness of the need for thorough, referenceable expressions of the way to build in and evaluate quality in nuclear software. A broader professional perspective can be seen in the growing number of software engineering standards sponsored by the Institute of Electrical and Electronics Engineers (IEEE) Computer Society. This family of standards represents a systematic effort to capture professional consensus on quality practices throughout the software development life cycle. The only omission-the implementation phase-is treated by accepted American National Standards Institute or de facto standards for programming languages

Nuclear electric propulsion mission engineering study. Volume 2: Final report

Science.gov (United States)

1973-01-01

Results of a mission engineering analysis of nuclear-thermionic electric propulsion spacecraft for unmanned interplanetary and geocentric missions are summarized. Critical technologies associated with the development of nuclear electric propulsion (NEP) are assessed, along with the impact of its availability on future space programs. Outer planet and comet rendezvous mission analysis, NEP stage design for geocentric and interplanetary missions, NEP system development cost and unit costs, and technology requirements for NEP stage development are studied.

Electric engineering introduction

International Nuclear Information System (INIS)

An, Byeong Won; Eom, Sang Ho

1999-03-01

It is divided into nine chapters, which includes electricity theory such as structure of material and current, nature of electricity, static, magnetic force and magnetic attraction, attraction of current and a storage battery, electric circuit on a direct current circuit, single phase circuit and 3-phase current circuit electricity machine like DC generator, DC motor, alternator, electric transformer, single-phase induction motor, 3-phase induction motor, synchronous motor, synchro electric machine, semiconductor such as diode, transistor, FET, UJT, silicon symmetrical switch, electronic circuit like smoothing circuit and Bistable MV. circuit, automatic control, measurement of electricity, electric application and safety.

SH-SY5Y human neuroblastoma cell line: in vitro cell model of dopaminergic neurons in Parkinson's disease.

Science.gov (United States)

Xie, Hong-rong; Hu, Lin-sen; Li, Guo-yi

2010-04-20

To evaluate the human neuroblastoma SH-SY5Y cell line as an in vitro model of dopaminergic (DAergic) neurons for Parkinson's disease (PD) research and to determine the effect of differentiation on this cell model. The data of this review were selected from the original reports and reviews related to SH-SY5Y cells published in Chinese and foreign journals (Pubmed 1973 to 2009). After searching the literature, 60 articles were selected to address this review. The SH-SY5Y cell line has become a popular cell model for PD research because this cell line posses many characteristics of DAergic neurons. For example, these cells express tyrosine hydroxylase and dopamine-beta-hydroxylase, as well as the dopamine transporter. Moreover, this cell line can be differentiated into a functionally mature neuronal phenotype in the presence of various agents. Upon differentiation, SH-SY5Y cells stop proliferating and a constant cell number is subsequently maintained. However, different differentiating agents induce different neuronal phenotypes and biochemical changes. For example, retinoic acid induces differentiation toward a cholinergic neuronal phenotype and increases the susceptibility of SH-SY5Y cells to neurotoxins and neuroprotective agents, whereas treatment with retinoic acid followed by phorbol ester 12-O-tetradecanoylphorbol-13-acetate results in a DAergic neuronal phenotype and decreases the susceptibility of cells to neurotoxins and neuroprotective agents. Some differentiating agents also alter kinetics of 1-methyl-4-phenyl-pyridinium (MPP(+)) uptake, making SH-SY5Y cells more similar to primary mesencephalic neurons. Differentiated and undifferentiated SH-SY5Y cells have been widely used as a cell model of DAergic neurons for PD research. Some differentiating agents afford SH-SY5Y cells with more potential for studying neurotoxicity and neuroprotection and are thus more relevant to experimental PD research.

Labor supply of engineers and scientists for nuclear electric utilities, 1987-1992

International Nuclear Information System (INIS)

Blair, L.M.

1988-01-01

An assessment of the adequacy of the supply of health physicists, nuclear engineers, and other engineers for the nuclear electric utility industry is based on job openings for scientists and engineers in broader nuclear-power-related fields, which include engineering and design, manufacturing, fabrication, supporting services, and government. In assessing the likely adequacy of labor supplies for commercial nuclear power job openings over the next 5 yr, consideration has been given to competing sources of labor demands, including nuclear energy research and development activities, nuclear defense, and the total US economy, and to the likely supply of new graduates. In particular, over the last 3 yr, the number of degrees awarded and enrollments in nuclear engineering programs have declined 12 and 14%, respectively, and in health physics programs, 5 and 14%, respectively. For health physics and nuclear engineers, tight labor market conditions (i.e. labor supplies and demand balanced at relatively high salaries) are expected over the next 5 yr because of declining enrollments and slowly growing employment levels plus job replacement needs. The commercial nuclear power field is expected to face tight labor markets for electrical and materials engineers because of strong competing demands in the economy. Other engineering occupations are likely to have adequate supplies for the nuclear power field but at salaries that continue to be relatively higher than salaries for other professional occupations

Development of educational complex on electrical engineering, electronics and microcon-trollers on modeling in TINA software

Directory of Open Access Journals (Sweden)

Vladimir A. Alekhin

2017-01-01

Full Text Available The study of electrical engineering, electronics and microcontrollers in accordance with federal state educational standards requires from students the practical mastering of experimental methods for the study of electrical circuits and electronic circuits, the formation of competences and skills in the calculation of electrical circuits and electronic circuits. The modern development of information educational technologies, the widespread use of a variety of computer facilities by students in reducing teaching hours for the study of disciplines make it necessary to create new multimedia training complexes, using computer simulation of electrical circuits, electronic circuits and microcontrollers in the lecture process and in the laboratory and practical exercises. The purpose of the research was a comparative analysis of various computer simulation programs in terms of their accessibility, ease of development and efficiency of use by lecturers and students in the educational process, and the creation and testing of a training complex for the electrical engineering, electronics and microcontrollers using the selected modeling environment.The problems associated with the need to purchase licensed software were discussed and a comparative analysis of the following computer modeling programs for electrical circuits and electronic circuits was performed: NI Multisim, Micro-Cap, Proteus VSM, OrCAD, TINA. The research method included the study of these modeling and design programs, writing of teaching aids and conducting of training sessions with students. The cost of licenses for the software application in computer classes and on students’ home computers was estimated. As a result, the conclusion was confirmed about the advisability of using the free student program of computer modeling TINA-TI and the TINACloud environment from DesignSoft for the teaching of electrical engineering and electronics.The new software product TINACloud uses cloud

The 1984 eclipse of the symbiotic binary SY Muscae

Science.gov (United States)

Kenyon, S. J.; Michalitisianos, A. G.; Lutz, J. H.; Kafatos, M.

1985-01-01

Data from IUE spectra obtained with the 10 x 20-arcsec aperture on May 13, 1984, and optical spectrophotometry obtained with an SIT vidicon on the 1.5-m telescope at CTIO on April 29-May 1, 1984, are reported for the symbiotic binary SY Mus. The data are found to be consistent with a model of a red-giant secondary of 60 solar radii which completely eclipses the hot primary every 627 d but only partially eclipses the 75-solar-radius He(+) region surrounding the primary. The distance to SY Mus is estimated as 1.3 kpc. It is suggested that the large Balmer decrement in eclipse, with (H-alpha)/(H-beta) = 8.3 and (H-beta)/(H-gamma) = 1.5, is associated with an electron density of about 10 to the 10th/cu cm.

Dynamic Analysis of Electrical Power Grid Delivery: Using Prime Mover Engines to Balance Dynamic Wind Turbine Output

Energy Technology Data Exchange (ETDEWEB)

Diana K. Grauer

2011-10-01

This paper presents an investigation into integrated wind + combustion engine high penetration electrical generation systems. Renewable generation systems are now a reality of electrical transmission. Unfortunately, many of these renewable energy supplies are stochastic and highly dynamic. Conversely, the existing national grid has been designed for steady state operation. The research team has developed an algorithm to investigate the feasibility and relative capability of a reciprocating internal combustion engine to directly integrate with wind generation in a tightly coupled Hybrid Energy System. Utilizing the Idaho National Laboratory developed Phoenix Model Integration Platform, the research team has coupled demand data with wind turbine generation data and the Aspen Custom Modeler reciprocating engine electrical generator model to investigate the capability of reciprocating engine electrical generation to balance stochastic renewable energy.

The Electrical Engineering Curriculum at the Technical University of Denmark - Options in Microelectronics

DEFF Research Database (Denmark)

Bruun, Erik; Nielsen, Lars Drud

1997-01-01

This paper describes the modular structure of the engineering curriculum at the Technical University of Denmark. The basic requirements for an electrical engineering curriculum are presented and different possibilities for specialization in microelectronics and integrated circuit design...

Fate of Zinc and Silver Engineered Nanoparticles in Sewerage Networks

Science.gov (United States)

Engineered zinc oxide (ZnO) and silver (Ag) nanoparticles (NPs) used in consumer products are largely released into the environment through the wastewater stream. Limited information is available regarding the transformations they undergo during their transit through sewerage sy...

UFISA: electric facility engineering for the service of emergy market

International Nuclear Information System (INIS)

Gutierrez Zapico, A.

1997-01-01

UFISA is the engineering company with the experience of UNION ELECTRICA FENOSA S.A. It activity began in 1990. This company offers to national and international markets the services for energy consumers and for the electricity costumers. (Author)

241-SY-101 data acquisition and control system (DACS) operator interface upgrade operational test report

International Nuclear Information System (INIS)

ERMI, A.M.

1999-01-01

This procedure provides instructions for readiness of the first portion of the upgraded 241-SY-101 Data Acquisition and Control System (DACS) computer system to provide proper control and monitoring of the mitigation mixer pump and instrumentation installed in the 241-SY-101 underground storage tank will be systematically evaluated by the performance of this procedure

Progress of Journal‘Advanced Technology of Electrical Engineering and Energy’

Institute of Scientific and Technical Information of China (English)

QIN Jie; LIN Liang-zhen; QI Zhi-ping; MA Yu-huan; SHEN Guo-liao; JING Bo-hong

2009-01-01

The paper has introduced the Journal 'Advanced Technology of Electrical Engineering and Energy', presented its main journal evaluation indexes. The result indicates that the journal has made great progress in recent years. It gives much info. about the journal to authors.

PSA results for Hanford high level waste Tank 101-SY

Energy Technology Data Exchange (ETDEWEB)

MacFarlane, D.R.; Bott, T.F.; Brown, L.F.; Stack, D.W. [Los Alamos National Lab., NM (United States); Kindinger, J.; Deremer, R.K.; Medhekar, S.R.; Mikschl, T.J. [PLG, Inc., Newport Beach, CA (United States)

1993-10-01

Los Alamos National Laboratory has performed a comprehensive probabilistic safety assessment (PSA) that includes consideration of external events for the weapons-production wastes stored in tank number 241-SY-101, commonly known as Tank 101-SY, as configured in December 1992. This tank, which periodically releases (``burps``) a gaseous mixture of hydrogen, nitrous oxide, ammonia, and nitrogen, was analyzed because of public safety concerns associated with the potential for release of radioactive tank contents should this gas mixture be ignited during one of the burps. In an effort to mitigate the burping phenomenon, an experiment is underway in which a large pump has been inserted into the tank to determine if pump-induced circulation of the tank contents will promote a slow, controlled release of the gases. This PSA for Tank 101-SY, which did not consider the pump experiment or future tank-remediation activities, involved three distinct tasks. First, the accident sequence analysis identified and quantified those potential accidents whose consequences result in tank material release. Second, characteristics and release paths for the airborne and liquid radioactive source terms were determined. Finally, the consequences, primarily onsite and offsite potential health effects resulting from radionuclide release, were estimated, and overall risk curves were constructed. An overview of each of these tasks and a summary of the overall results of the analysis are presented in the following sections.

PSA results for Hanford high level waste Tank 101-SY

International Nuclear Information System (INIS)

MacFarlane, D.R.; Bott, T.F.; Brown, L.F.; Stack, D.W.; Kindinger, J.; Deremer, R.K.; Medhekar, S.R.; Mikschl, T.J.

1993-01-01

Los Alamos National Laboratory has performed a comprehensive probabilistic safety assessment (PSA) that includes consideration of external events for the weapons-production wastes stored in tank number 241-SY-101, commonly known as Tank 101-SY, as configured in December 1992. This tank, which periodically releases (''burps'') a gaseous mixture of hydrogen, nitrous oxide, ammonia, and nitrogen, was analyzed because of public safety concerns associated with the potential for release of radioactive tank contents should this gas mixture be ignited during one of the burps. In an effort to mitigate the burping phenomenon, an experiment is underway in which a large pump has been inserted into the tank to determine if pump-induced circulation of the tank contents will promote a slow, controlled release of the gases. This PSA for Tank 101-SY, which did not consider the pump experiment or future tank-remediation activities, involved three distinct tasks. First, the accident sequence analysis identified and quantified those potential accidents whose consequences result in tank material release. Second, characteristics and release paths for the airborne and liquid radioactive source terms were determined. Finally, the consequences, primarily onsite and offsite potential health effects resulting from radionuclide release, were estimated, and overall risk curves were constructed. An overview of each of these tasks and a summary of the overall results of the analysis are presented in the following sections

Dictionary electrical engineering. German-English, English-German. 3. ed.

International Nuclear Information System (INIS)

Petersen, Hans-Joachim

2017-01-01

This dictionary facilitates correct handling of technical terms in electrical engineering. The essential enlargement of vocabulary in this edition offers a well-founded basis of the electrotechnical terms for education as well as for everyday use. An appendix with frequently used phrases complements this dictionary together with the ''International System of Units''. [de

Seymour (Sy) Epstein (1924-2016).

Science.gov (United States)

O'Brien, Edward; O'Brien, Jean; Waters, Everett

2018-01-01

Presents an obituary for Seymour (Sy) Epstein, who passed away in Amherst on May 20, 2016. Epstein was a significant voice in personality psychology for more than six decades. His wide-ranging, programmatic research addressed cognitive mediation of classical conditioning, stress and coping, the self-concept, drive, conflict, and psychopathology. His research on aggregation strongly influenced the person-situation debate. His most important contribution was his decades-long development of an integrated personality theory, culminating in his magnum opus, Cognitive-Experiential Theory (Oxford University Press, 2014). (PsycINFO Database Record (c) 2018 APA, all rights reserved).

sY116, a human Y-linked polymorphic STS

Indian Academy of Sciences (India)

linked STS, showed different electrophoretic mobilities in three males, two infertile and one fertile. A study of this STS among 35 other normal males showed that this locus is polymorphic. sY116 has a poly A-rich stretch whose instability ...

Compressed air piping, 241-SY-101 hydraulic pump retrieval trailer

International Nuclear Information System (INIS)

Wilson, T.R.

1994-01-01

The following Design Analysis was prepared by the Westinghouse Hanford Company to determine pressure losses in the compressed air piping installed on the hydraulic trailer for the 241-SY-101 pump retrieval mission

Engineering and Design: Reliability Analysis of Navigation Lock and Dam Mechanical and Electrical Equipment

National Research Council Canada - National Science Library

Beranek, Dwight

2001-01-01

This engineer technical letter (ETL) provides guidance for assessing the reliability of mechanical and electrical systems of navigation locks and dams and for establishing an engineering basis for major rehabilitation investment decisions...

The electric power engineering handbook power system stability and control

CERN Document Server

Grisby, Leonard L

2012-01-01

With contributions from worldwide leaders in the field, Power System Stability and Control, Third Edition (part of the five-volume set, The Electric Power Engineering Handbook) updates coverage of recent developments and rapid technological growth in essential aspects of power systems. Edited by L.L. Grigsby, a respected and accomplished authority in power engineering, and section editors Miroslav Begovic, Prabha Kundur, and Bruce Wollenberg, this reference presents substantially new and revised content. Topics covered include: * Power System Protection * Power System Dynamics and Stability *

Morphological Differentiation Towards Neuronal Phenotype of SH-SY5Y Neuroblastoma Cells by Estradiol, Retinoic Acid and Cholesterol

OpenAIRE

Teppola, Heidi; Sarkanen, Jertta-Riina; Jalonen, Tuula O.; Linne, Marja-Leena

2015-01-01

Human SH-SY5Y neuroblastoma cells maintain their potential for differentiation and regression in culture conditions. The induction of differentiation could serve as a strategy to inhibit cell proliferation and tumor growth. Previous studies have shown that differentiation of SH-SY5Y cells can be induced by all-trans-retinoic-acid (RA) and cholesterol (CHOL). However, signaling pathways that lead to terminal differentiation of SH-SY5Y cells are still largely unknown. The goal of this study was...

Morphological Differentiation Towards Neuronal Phenotype of SH-SY5Y Neuroblastoma Cells by Estradiol, Retinoic Acid and Cholesterol

OpenAIRE

Teppola, Heidi; Sarkanen, Jertta-Riina; Jalonen, Tuula; Linne, Marja-Leena

2016-01-01

Human SH-SY5Y neuroblastoma cells maintain their potential for differentiation and regression in culture conditions. The induction of differentiation could serve as a strategy to inhibit cell proliferation and tumor growth. Previous studies have shown that differentiation of SH-SY5Y cells can be induced by all-trans-retinoic-acid (RA) and cholesterol (CHOL). However, signaling pathways that lead to terminal differentiation of SH-SY5Y cells are still largely unknown. The goal of this study was...

Hydrogen Peroxide Toxicity Induces Ras Signaling in Human Neuroblastoma SH-SY5Y Cultured Cells

Directory of Open Access Journals (Sweden)

Jirapa Chetsawang

2010-01-01

Full Text Available It has been reported that overproduction of reactive oxygen species occurs after brain injury and mediates neuronal cells degeneration. In the present study, we examined the role of Ras signaling on hydrogen peroxide-induced neuronal cells degeneration in dopaminergic neuroblastoma SH-SY5Y cells. Hydrogen peroxide significantly reduced cell viability in SH-SY5Y cultured cells. An inhibitor of the enzyme that catalyzes the farnesylation of Ras proteins, FTI-277, and a competitive inhibitor of GTP-binding proteins, GDP-beta-S significantly decreased hydrogen peroxide-induced reduction in cell viability in SH-SY5Y cultured cells. The results of this study might indicate that a Ras-dependent signaling pathway plays a role in hydrogen peroxide-induced toxicity in neuronal cells.

Oxidative stress response in SH-SY5Y cells exposed to short-term 1800 MHz radiofrequency radiation.

Science.gov (United States)

Marjanovic Cermak, Ana Marija; Pavicic, Ivan; Trosic, Ivancica

2018-01-28

The exact mechanism that could explain the effects of radiofrequency (RF) radiation exposure at non-thermal level is still unknown. Increasing evidence suggests a possible involvement of reactive oxygen species (ROS) and development of oxidative stress. To test the proposed hypothesis, human neuroblastoma cells (SH-SY5Y) were exposed to 1800 MHz short-term RF exposure for 10, 30 and 60 minutes. Electric field strength within Gigahertz Transverse Electromagnetic cell (GTEM) was 30 V m -1 and specific absorption rate (SAR) was calculated to be 1.6 W kg -1 . Cellular viability was measured by MTT assay and level of ROS was determined by fluorescent probe 2',7'-dichlorofluorescin diacetate. Concentrations of malondialdehyde and protein carbonyls were used to assess lipid and protein oxidative damage and antioxidant activity was evaluated by measuring concentrations of total glutathione (GSH). After radiation exposure, viability of irradiated cells remained within normal physiological values. Significantly higher ROS level was observed for every radiation exposure time. After 60 min of exposure, the applied radiation caused significant lipid and protein damage. The highest GSH concentration was detected after 10 minute-exposure. The results of our study showed enhanced susceptibility of SH-SY5Y cells for development of oxidative stress even after short-term RF exposure.

Principles and software realization of a multimedia course on theoretical electrical engineering based on enterprise technology

Directory of Open Access Journals (Sweden)

Penev Krasimir

2003-01-01

Full Text Available The Department of Theoretical Electrical Engineering (TEE of Technical University of Sofia has been developing interactive enterprise-technologies based course on Theoretical Electrical Engineering. One side of the project is the development of multimedia teaching modules for the core undergraduate electrical engineering courses (Circuit Theory and Electromagnetic Fields and the other side is the development of Software Architecture of the web site on which modules are deployed. Initial efforts have been directed at the development of multimedia modules for the subject Electrical Circuits and on developing the web site structure. The objective is to develop teaching materials that will enhance lectures and laboratory exercises and will allow computerized examinations on the subject. This article outlines the framework used to develop the web site structure, the Circuit Theory teaching modules, and the strategy of their use as teaching tool.

Starting the aircraft engines and gas-turbine drive by means of electric starter

Directory of Open Access Journals (Sweden)

І.М. Іщенко

2004-04-01

Full Text Available  In the article the questions of the starting the aircraft engines and gas-turbine drive by means of electric starter is considered. In the same way in the article are determined the main requirements to steady-state converter for feeding electric starter.

Electrical, electronics, and digital hardware essentials for scientists and engineers

CERN Document Server

Lipiansky, Ed

2012-01-01

A practical guide for solving real-world circuit board problems Electrical, Electronics, and Digital Hardware Essentials for Scientists and Engineers arms engineers with the tools they need to test, evaluate, and solve circuit board problems. It explores a wide range of circuit analysis topics, supplementing the material with detailed circuit examples and extensive illustrations. The pros and cons of various methods of analysis, fundamental applications of electronic hardware, and issues in logic design are also thoroughly examined. The author draws on more than tw

Theory of semiconductor junction devices a textbook for electrical and electronic engineers

CERN Document Server

Leck, J H

1967-01-01

Theory of Semiconductor Junction Devices: A Textbook for Electrical and Electronic Engineers presents the simplified numerical computation of the fundamental electrical equations, specifically Poisson's and the Hall effect equations. This book provides the fundamental theory relevant for the understanding of semiconductor device theory. Comprised of 10 chapters, this book starts with an overview of the application of band theory to the special case of semiconductors, both intrinsic and extrinsic. This text then describes the electrical properties of conductivity, semiconductors, and Hall effe

SenSyF Experience on Integration of EO Services in a Generic, Cloud-Based EO Exploitation Platform

Science.gov (United States)

Almeida, Nuno; Catarino, Nuno; Gutierrez, Antonio; Grosso, Nuno; Andrade, Joao; Caumont, Herve; Goncalves, Pedro; Villa, Guillermo; Mangin, Antoine; Serra, Romain; Johnsen, Harald; Grydeland, Tom; Emsley, Stephen; Jauch, Eduardo; Moreno, Jose; Ruiz, Antonio

2016-08-01

SenSyF is a cloud-based data processing framework for EO- based services. It has been pioneer in addressing Big Data issues from the Earth Observation point of view, and is a precursor of several of the technologies and methodologies that will be deployed in ESA's Thematic Exploitation Platforms and other related systems.The SenSyF system focuses on developing fully automated data management, together with access to a processing and exploitation framework, including Earth Observation specific tools. SenSyF is both a development and validation platform for data intensive applications using Earth Observation data. With SenSyF, scientific, institutional or commercial institutions developing EO- based applications and services can take advantage of distributed computational and storage resources, tailored for applications dependent on big Earth Observation data, and without resorting to deep infrastructure and technological investments.This paper describes the integration process and the experience gathered from different EO Service providers during the project.

Nuclear electric propulsion mission engineering study. Volume 1: Executive summary

Science.gov (United States)

1973-01-01

Results of a mission engineering analysis of nuclear-thermionic electric propulsion spacecraft for unmanned interplanetary and geocentric missions are summarized. Critical technologies associated with the development of nuclear electric propulsion (NEP) are assessed. Outer planet and comet rendezvous mission analysis, NEP stage design for geocentric and interplanetary missions, NEP system development cost and unit costs, and technology requirements for NEP stage development are studied. The NEP stage design provides both inherent reliability and high payload mass capability. The NEP stage and payload integration was found to be compatible with the space shuttle.

Tank characterization report for double-shell tank 241-SY-103

International Nuclear Information System (INIS)

Conner, J.M.

1996-01-01

This document summarizes the information on the historical uses, present status, and the sampling and analysis results of waste stored in tank 241-SY-103. This report supports the requirements of Tri-Party Agreement Milestone M-44 09

Work plan for upgrade of SY-101 Hydrogen Mitigation Test Project Data Acquisition and Control Systemm (DACS-1)

International Nuclear Information System (INIS)

Truitt, R.W.

1994-08-01

The purpose of this effort is to upgrade the existing DACS-1 used for control and data acquisition in support of the hydrogen mitigation program for tank 101-SY. The planned upgrades will enhance the system capabilities to support additional mitigation projects and improve the system operability by implementing changes identified during operation of the system to date. Once the upgrades have been implemented, the DACS-1 system should operate as it did prior to the upgrade, but with greatly increased speed and capability. No retraining of Test Engineers will be required; the upgrade is designed to be transparent to those who operate it, with only a noticeable increase in the speed of the system. This work plan defines the tasks required for implementing the upgrade. It identifies deliverables, responsible organizations and individuals, interfaces, and schedule. This upgrade effort employs system engineering principles wherever applicable

Cradle-to-gate greenhouse gas emissions of battery electric and internal combustion engine vehicles in China

International Nuclear Information System (INIS)

Qiao, Qinyu; Zhao, Fuquan; Liu, Zongwei; Jiang, Shuhua; Hao, Han

2017-01-01

Highlights: •Cradle-to-gate greenhouse gas emissions of internal combustion engine and battery electric vehicles are compared. •Greenhouse gas emissions of battery electric vehicles are 50% higher than internal combustion engine vehicles. •Traction battery production causes about 20% greenhouse gas emissions increase. •10% variations of curb weight, electricity and Li-ion battery production affect the results by 7%, 4% and 2%. •Manufacturing technique improvement, vehicle recycling and energy structure optimization are major mitigation opportunities. -- Abstract: Electric drive vehicles are equipped with totally different propulsion systems compared with conventional vehicles, for which the energy consumption and cradle-to-gate greenhouse gas emissions associated with vehicle production could substantially change. In this study, the life cycle energy consumption and greenhouse gas emissions of vehicle production are compared between battery electric and internal combustion engine vehicles in China’s context. The results reveal that the energy consumption and greenhouse gas emissions of a battery electric vehicle production range from 92.4 to 94.3 GJ and 15.0 to 15.2 t CO 2 eq, which are about 50% higher than those of an internal combustion engine vehicle, 63.5 GJ and 10.0 t CO 2 eq. This substantial change can be mainly attributed to the production of traction batteries, the essential components for battery electric vehicles. Moreover, the larger weight and different weight distribution of materials used in battery electric vehicles also contribute to the larger environmental impact. This situation can be improved through the development of new traction battery production techniques, vehicle recycling and a low-carbon energy structure.

Simulation of a heavy-duty diesel engine with electrical turbocompounding system using operating charts for turbocharger components and power turbine

International Nuclear Information System (INIS)

Katsanos, C.O.; Hountalas, D.T.; Zannis, T.C.

2013-01-01

Highlights: • A diesel model was developed using charts for turbocharger and power turbine. • The maximum value of bsfc improvement is 4.1% at 100% engine load. • The generated electric power ranges from 23 kW to 62 kW. • Turbocharger turbine efficiency decreases slightly with the power turbine speed. • Turbocompounding increases the average pressure value in the exhaust manifold. - Abstract: In diesel engines, approximately 30–40% of the energy supplied by the fuel is rejected to the ambience through exhaust gases. Therefore, there is a potentiality for further considerable increase of diesel engine efficiency with the utilization of exhaust gas heat and its conversion to mechanical or electrical energy. In the present study, the operational behavior of a heavy-duty (HD) diesel truck engine equipped with an electric turbocompounding system is examined on a theoretical basis. The electrical turbocompounding configuration comprised of a power turbine coupled to an electric generator, which is installed downstream to the turbocharger (T/C) turbine. A diesel engine simulation model has been developed using operating charts for both turbocharger and power turbine. A method for introducing the operating charts into the engine model is described thoroughly. A parametric analysis is conducted with the developed simulation tool, where the varying parameter is the rotational speed of power turbine shaft. In this study, the interaction between the power turbine and the turbocharged diesel engine is examined in detail. The effect of power turbine speed on T/C components efficiencies, power turbine efficiency, exhaust pressure and temperature, engine boost pressure and air to fuel ratio is evaluated. In addition, theoretical results for the potential impact of electrical turbocompounding on the generated electric power, net engine power and relative improvement of brake specific fuel consumption (bsfc) are provided. The critical evaluation of the theoretical

Tank characterization report for double-shell tank 241-SY-103

International Nuclear Information System (INIS)

Hansen, D.R.

1996-01-01

This document summarizes the information on the historical uses, present status, and the sampling and analysis results of waste stored in Tank 241-SY-103. This report supports the requirements of the Tri-Party Agreement Milestone M-44-09

New trends for non-ferrous metals in the electrical engineering industry

International Nuclear Information System (INIS)

Singer, R.F.

1989-01-01

The non-ferrous metals copper, aluminium and nickel are of major importance to the electrical engineering industry. Copper is used for magnet wire, underground cable and overhead contact wire, and aluminium is important for overhead power transmission lines. Nickel alloys are employed as gas turbine blades in power generation. An important new trend in the conductor area is rapid solidification for improved combinations of strength and conductivity. Another new trend is the Conform continuous extrusion process which can decrease cost and increase quality. New high temperature superconductors might change the conductor market completely, but only on the long run. Nickel base blading materials will see considerable improvements from oxide dispersion strengthening and directional solidification. In summary, non-ferrous materials technology for electrical engineering applications is on the move and considerable improvements can be expected within the next decade. (orig.) [de

LS1: electrical engineering upgrades and consolidation

International Nuclear Information System (INIS)

Duval, F.

2012-01-01

3 different types of activities are planned by the Engineering Department Electrical Engineering (EN-EL) Group for the first long shut down (LS1). First, the consolidation of EN-EL's ageing infrastructure elements. It is part of a 15- year programme aiming at increasing the reliability and availability of the power distribution network. Secondly, the maintenance of the accelerators infrastructure. In addition to the usual periodic operations and those delayed until LS1, the group will address more demanding activities like the replacement campaigns for irradiated cables and non-radiation resistant fibres as well as the removal of unused cables in particularly overcrowded areas. Thirdly, a vast amount of user copper and optical fibre cabling requests: EN-EL estimates that only 50% of LS1 requests are currently known. The main activities will be EN-EL's contributions to the R2E project, BE-BI upgrade projects, and the RF upgrade project in SPS BA3

syNErgy: A Case Study in Workforce Curriculum Development

Science.gov (United States)

Killingsworth, John; Grosskopf, Kevin R.

2013-01-01

With high unemployment and structural changes to industry, workforce development in the United States is a growing concern. Many semiskilled workers lack knowledge, skills, and abilities to be competitive for reemployment to green jobs. Nebraska's syNErgy research grant was introduced to address the training needs of unemployed and underemployed…

Acceptance Test Procedure: SY101 air pallet system

International Nuclear Information System (INIS)

Koons, B.M.

1995-01-01

The purpose of this test procedure is to verify that the system(s) procured to load the SY-101 Mitigation Test Pump package fulfills its functional requirements. It will also help determine the man dose expected due to handling of the package during the actual event. The scope of this procedure focuses on the ability of the air pallets and container saddles to carry the container package from the new 100 foot concrete pad into 2403-WD where it will be stored awaiting final disposition. This test attempts to simulate the actual event of depositing the SY-101 hydrogen mitigation test pump into the 2403-WD building. However, at the time of testing road modifications required to drive the 100 ton trailer into CWC were not performed. Therefore a flatbed trailer will be use to transport the container to CWC. The time required to off load the container from the 100 ton trailer will be recorded for man dose evaluation on location. The cranes used for this test will also be different than the actual event. This is not considered to be an issue due to minimal effects on man dose

Development of Servo Motor Trainer for Basic Control System in Laboratory of Electrical Engineering Control System Faculty of Engineering Universitas Negeri Surabaya

Science.gov (United States)

Endryansyah; Wanarti Rusimamto, Puput; Ridianto, Adam; Sugiarto, Hariyadi

2018-04-01

In the Department of Electrical Engineering FT Unesa, there are 3 majors: S1 Electrical Engineering Education, S1 Electrical Engineering, and D3 Electrical Engineering. Courses the Basic System Settings go to in the curriculum of the three programs. Team lecturer college of basic system settings seek learning innovation, focused on the development of trainer to student practicum at the laboratory of systems control. Trainer developed is a servo motor along with the lab module that contains a wide variety of theories about the servo motor and guide the practicum. This research type is development research using methods Research & development (R & D). In which the steps are applied in this study is as follows: pay attention to the potential and existing problems, gather information and study the literature, design the product, validate the design, revise the design, a limited trial. The results of the validation of learning device in the form of modules and trainer obtained as follows: score validation of learning device is 3,64; score validation lab module Servo Motor is 3,47; and questionnaire responses of students is 3,73. The result of the whole validation value is located in the interval >of 3.25 s/d 4 with the category of “Very Valid”, so it can be concluded that all instruments have a level of validity “Very Valid” and worthy of use for further learning.

Morphological Differentiation Towards Neuronal Phenotype of SH-SY5Y Neuroblastoma Cells by Estradiol, Retinoic Acid and Cholesterol.

Science.gov (United States)

Teppola, Heidi; Sarkanen, Jertta-Riina; Jalonen, Tuula O; Linne, Marja-Leena

2016-04-01

Human SH-SY5Y neuroblastoma cells maintain their potential for differentiation and regression in culture conditions. The induction of differentiation could serve as a strategy to inhibit cell proliferation and tumor growth. Previous studies have shown that differentiation of SH-SY5Y cells can be induced by all-trans-retinoic-acid (RA) and cholesterol (CHOL). However, signaling pathways that lead to terminal differentiation of SH-SY5Y cells are still largely unknown. The goal of this study was to examine in the RA and CHOL treated SH-SY5Y cells the additive impacts of estradiol (E2) and brain-derived neurotrophic factor (BDNF) on cell morphology, cell population growth, synaptic vesicle recycling and presence of neurofilaments. The above features indicate a higher level of neuronal differentiation. Our data show that treatment for 10 days in vitro (DIV) with RA alone or when combined with E2 (RE) or CHOL (RC), but not when combined with BDNF (RB), significantly (p differentiation.

Syöpäpotilaiden toiveet hoitoympäristöstä päiväsairaalassa

OpenAIRE

Mäki, Saara; Ojalainen, Kati

2015-01-01

Tämän opinnäytetyön tarkoituksena oli selvittää syöpäpotilaiden toiveita päiväsairaalan fyysisestä hoitoympäristöstä. Tavoitteena oli saada selville ideaali päiväsairaalatila, jossa potilaat kokevat olonsa mahdollisimman turvalliseksi ja miellyttäväksi. Tämän opinnäytetyön tuloksia voidaan hyödyntää suunnitellessa uuden syöpäsairaalan päiväosastojen hoitotiloja. Opinnäytetyö on toteutettu yhteistyössä Helsingin ja Uudenmaan sairaanhoitopiirin HYKS :in Syöpäkeskuksen kanssa. Tämän opinnäyt...

Electrical Engineering | Classification | College of Engineering & Applied

Science.gov (United States)

Engineering Concentration on Ergonomics M.S. Program in Computer Science Interdisciplinary Concentration on Energy Doctoral Programs in Engineering Non-Degree Candidate Departments Biomedical Engineering Biomedical Engineering Industry Advisory Council Civil & Environmental Engineering Civil &

The SH-SY5Y cell line in Parkinson's disease research: a systematic review.

Science.gov (United States)

Xicoy, Helena; Wieringa, Bé; Martens, Gerard J M

2017-01-24

Parkinson's disease (PD) is a devastating and highly prevalent neurodegenerative disease for which only symptomatic treatment is available. In order to develop a truly effective disease-modifying therapy, improvement of our current understanding of the molecular and cellular mechanisms underlying PD pathogenesis and progression is crucial. For this purpose, standardization of research protocols and disease models is necessary. As human dopaminergic neurons, the cells mainly affected in PD, are difficult to obtain and maintain as primary cells, current PD research is mostly performed with permanently established neuronal cell models, in particular the neuroblastoma SH-SY5Y lineage. This cell line is frequently chosen because of its human origin, catecholaminergic (though not strictly dopaminergic) neuronal properties, and ease of maintenance. However, there is no consensus on many fundamental aspects that are associated with its use, such as the effects of culture media composition and of variations in differentiation protocols. Here we present the outcome of a systematic review of scientific articles that have used SH-SY5Y cells to explore PD. We describe the cell source, culture conditions, differentiation protocols, methods/approaches used to mimic PD and the preclinical validation of the SH-SY5Y findings by employing alternative cellular and animal models. Thus, this overview may help to standardize the use of the SH-SY5Y cell line in PD research and serve as a future user's guide.

Software Packages to Support Electrical Engineering Virtual Lab

Directory of Open Access Journals (Sweden)

Manuel Travassos Valdez

2012-03-01

Full Text Available The use of Virtual Reality Systems (VRS, as a learning aid, encourages the creation of tools that allow users/students to simulate educational environments on a computer. This article presents a way of building a VRS system with Software Packages to support Electrical Engineering Virtual Laboratories to be used in a near future in the teaching of the curriculum unit of Circuit Theory. The steps required for the construction of a project are presented in this paper. The simulation is still under construction and intends to use a three-dimensional virtual environment laboratory electric measurement, which will allow users/students to experiment and test the modeled equipment. Therefore, there are still no links available for further examination. The result may demonstrate the future potential of applications of Virtual Reality Systems as an efficient and cost-effective learning system.

Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research.

Science.gov (United States)

Cheung, Yuen-Ting; Lau, Way Kwok-Wai; Yu, Man-Shan; Lai, Cora Sau-Wan; Yeung, Sze-Chun; So, Kwok-Fai; Chang, Raymond Chuen-Chung

2009-01-01

Human neuroblastoma SH-SY5Y is a dopaminergic neuronal cell line which has been used as an in vitro model for neurotoxicity experiments. Although the neuroblastoma is usually differentiated by all-trans-retinoic acid (RA), both RA-differentiated and undifferentiated SH-SY5Y cells have been used in neuroscience research. However, the changes in neuronal properties triggered by RA as well as the subsequent responsiveness to neurotoxins have not been comprehensively studied. Therefore, we aim to re-evaluate the differentiation property of RA on this cell line. We hypothesize that modulation of signaling pathways and neuronal properties during RA-mediated differentiation in SH-SY5Y cells can affect their susceptibility to neurotoxins. The differentiation property of RA was confirmed by showing an extensive outgrowth of neurites, increased expressions of neuronal nuclei, neuron specific enolase, synaptophysin and synaptic associated protein-97, and decreased expression of inhibitor of differentiation-1. While undifferentiated SH-SY5Y cells were susceptible to 6-OHDA and MPP+, RA-differentiation conferred SH-SY5Y cells higher tolerance, potentially by up-regulating survival signaling, including Akt pathway as inhibition of Akt removed RA-induced neuroprotection against 6-OHDA. As a result, the real toxicity cannot be revealed in RA-differentiated cells. Therefore, undifferentiated SH-SY5Y is more appropriate for studying neurotoxicity or neuroprotection in experimental Parkinson's disease research.

Operational experience in mitigating flammable gas releases from Hanford Site Tank 241-SY-101

International Nuclear Information System (INIS)

Lentsch, J.W.; Babad, H.; Kirch, N.W.

1995-01-01

Flammable gases consisting of hydrogen, nitrous oxide, ammonia, and methane are periodically released from Hanford Site waste tank 241-SY-101 at concentrations above the flammable limit. A large mixer pump installed in the tank in 1993 has effectively mitigated this problem by continuously releasing small amounts of the flammable gases at the rate they are generated. Tank 241-SY-101 is also equipped with multiple high-sensitivity gas monitoring systems and level detection systems to measure the quantity of gas that is retained in and released from the waste

Yksityisen syöpäsairaalan tietoturvakartoitus

OpenAIRE

Kitunen, Martti

2014-01-01

Tämän opinnäytetyön aiheena oli kartoittaa yksityisen syöpäsairaalan tietoturvallisuutta. Työssä haluttiin tuoda esille tietoturvallisuutta sairaalan näkökulmasta. Tutkimuksen teoriaosuudessa osuudessa perehdyttiin tietoturvan osa-alueisiin ja -käsitteisiin. Työssä tarkasteltiin tietoturvallisuuden merkitystä yrityksille, sekä mahdollisia tietoturvauhkia. Lisäksi käytiin läpi tietoturvan arviointiin käytettäviä teknisiä ratkaisuja. Tutkimuksen tavoitteena oli kartoittaa Docrateen tietotur...

State of R and D of radioactive waste disposal (5). R and D of low level radioactive waste disposal. Engineered barrier: evaluation of barrier materials

International Nuclear Information System (INIS)

Hironaga, Michihiko

2008-01-01

The Central Research Institute of Electric Power Industry (CRIEPI) has researched and developed the long-term durability evaluation of engineered barrier materials for the facility of sub-surface disposal at intermediate depth. The important functions of engineered barrier are mechanical stability of construction, low hydraulic conductivity and diffusivity, and absorption of nuclide. A natural barrier plays an important part in nuclide transfer. Some examples of researches on the engineered barrier with cement and bentonite are reported. They contained the leaching test of hardened cement paste using X-ray microanalysis, relation between the dissociation rate of montmorillonite and pH from 15 to 70 deg C, and the mechanism of gas permeability of dense bentonite. The results of leaching test showed that the modified underground water leached smaller amount of ions than the ion exchanged water. The sediment was found on the surface of hardened paste. The dissociation rate of smectite under alkaline conditions showed almost the same values as neutral conditions at 15 deg C. (S.Y.)

Tank SY-102 waste retrieval assessment: Rheological measurements and pump jet mixing simulations

International Nuclear Information System (INIS)

Onishi, Y.; Shekarriz, R.; Recknagle, K.P.

1996-09-01

Wastes stored in Hanford Tank 241-SY-102 are planned to be retrieved from that tank and transferred to 200 East Area through the new pipeline Replacement Cross Site Transfer System (RCSTS). Because the planned transfer of this waste will use the RCSTS, the slurry that results from the mobilization and retrieval operations must meet the applicable waste acceptance criteria for this system. This report describes results of the second phase (the detailed assessment) of the SY-102 waste retrieval study, which is a part of the efforts to establish a technical basis for mobilization of the slurry, waste retrieval, and slurry transport. Hanford Tank 241-SY-102 is located in the SY Tank Farm in the Hanford Site's 200 West Area. It was built in 1977 to serve as a feed tank for 242-S Evaporator/Crystallizer, receiving supernatant liquid from S, SX, T, and U tank farms. Since 1981, the primary sources of waste have been from 200 West Area facilities, e.g., T-Plant decontamination operations, Plutonium Finishing Plant operations, and the 222-S Laboratory. It is the only active-service double-shell tank (DST) in the 200 West Area and is used as the staging tank for cross-site transfers to 200 East Area DSTs. The tank currently stores approximately 470 kL (125 kgal) of sludge wastes from a variety of sources including the Plutonium Finishing Plant, T-Plant, and the 222-S Laboratory. In addition to the sludge, approximately twice this amount (about 930 kL) of dilute, noncomplexed waste forms a supernatant liquid layer above the sludge

Matlab for electrical and computer engineering students and professionals with Simulink

CERN Document Server

Priemer, Roland

2013-01-01

This book combines the teaching of the MATLAB#65533; programming language with the presentation and development of carefully selected electrical and computer engineering (ECE) fundamentals. This is what distinguishes it from other books concerned with MATLAB#65533;: it is directed specifically to ECE concerns.

Microstructure and phase transformations in laser clad CrxSy/Ni coating on H13 steel

Science.gov (United States)

Lei, Yiwen; Sun, Ronglu; Tang, Ying; Niu, Wei

2015-03-01

Laser cladding was carried out onto H13 steel with preplaced NiCrBSi+Ni/MoS2 powders using CO2 laser under the optimized experimental parameters of laser power 2 kW, scanning velocity 6 mm/s and laser beam diameter 3 mm. An X-ray diffractometer and scanning electron microscope with energy dispersive spectroscopy were applied to analyze the microstructure and phase compositions of the coating. Thermodynamic calculation was performed with Thermo-Calc software on the basis of a commercially available Ni-based Alloys' database. The experimental results show that MoS2 decomposed and S reacted with Cr to form nonstoichiometric CrxSy during the laser cladding process. The coating consists of spherical CrxSy particles, primary γ-Ni dendrite, interdendritic eutectic (γ-Ni+NiMo) and precipitated NiMo. The precipitated NiMo was fine and uniformly distributed in primary γ-Ni dendrite. The calculated results and experimental data indicate that the solidification process in the coating during laser cladding process was liquid→liquid+CrxSy→ liquid+CrxSy+γ-Ni→liquid+CrxSy+γ-Ni+ eutectic (γ-Ni+NiMo). A solid state phase transformation (fine and uniformly distributed NiMo precipitated from γ-Ni) occurred after the solidification process. The calculations agree well with the experimental data and it is helpful to understand the phase transformation and microstructure evolution in the coating.

The Nigerian Society of Engineers (Electrical Division). National Workshop on Energy Conservation in Buildings. Proceedings

International Nuclear Information System (INIS)

Esan, A. A.

2000-03-01

This is a combined proceedings of the two national workshops held in Abuja and Lagos, by the Electrical Division of the Nigerian Society of Engineers. We wish to thank the Nigerian Society of Engineers for making available this document

Electrical Maxwell Demon and Szilard Engine Utilizing Johnson Noise, Measurement, Logic and Control

Science.gov (United States)

Kish, Laszlo Bela; Granqvist, Claes-Göran

2012-01-01

We introduce a purely electrical version of Maxwell's demon which does not involve mechanically moving parts such as trapdoors, etc. It consists of a capacitor, resistors, amplifiers, logic circuitry and electronically controlled switches and uses thermal noise in resistors (Johnson noise) to pump heat. The only types of energy of importance in this demon are electrical energy and heat. We also demonstrate an entirely electrical version of Szilard's engine, i.e., an information-controlled device that can produce work by employing thermal fluctuations. The only moving part is a piston that executes work, and the engine has purely electronic controls and it is free of the major weakness of the original Szilard engine in not requiring removal and repositioning the piston at the end of the cycle. For both devices, the energy dissipation in the memory and other binary informatics components are insignificant compared to the exponentially large energy dissipation in the analog part responsible for creating new information by measurement and decision. This result contradicts the view that the energy dissipation in the memory during erasure is the most essential dissipation process in a demon. Nevertheless the dissipation in the memory and information processing parts is sufficient to secure the Second Law of Thermodynamics. PMID:23077525

Electrical Maxwell demon and Szilard engine utilizing Johnson noise, measurement, logic and control.

Directory of Open Access Journals (Sweden)

Laszlo Bela Kish

Full Text Available We introduce a purely electrical version of Maxwell's demon which does not involve mechanically moving parts such as trapdoors, etc. It consists of a capacitor, resistors, amplifiers, logic circuitry and electronically controlled switches and uses thermal noise in resistors (Johnson noise to pump heat. The only types of energy of importance in this demon are electrical energy and heat. We also demonstrate an entirely electrical version of Szilard's engine, i.e., an information-controlled device that can produce work by employing thermal fluctuations. The only moving part is a piston that executes work, and the engine has purely electronic controls and it is free of the major weakness of the original Szilard engine in not requiring removal and repositioning the piston at the end of the cycle. For both devices, the energy dissipation in the memory and other binary informatics components are insignificant compared to the exponentially large energy dissipation in the analog part responsible for creating new information by measurement and decision. This result contradicts the view that the energy dissipation in the memory during erasure is the most essential dissipation process in a demon. Nevertheless the dissipation in the memory and information processing parts is sufficient to secure the Second Law of Thermodynamics.

Electrical Maxwell demon and Szilard engine utilizing Johnson noise, measurement, logic and control.

Science.gov (United States)

Kish, Laszlo Bela; Granqvist, Claes-Göran

2012-01-01

We introduce a purely electrical version of Maxwell's demon which does not involve mechanically moving parts such as trapdoors, etc. It consists of a capacitor, resistors, amplifiers, logic circuitry and electronically controlled switches and uses thermal noise in resistors (Johnson noise) to pump heat. The only types of energy of importance in this demon are electrical energy and heat. We also demonstrate an entirely electrical version of Szilard's engine, i.e., an information-controlled device that can produce work by employing thermal fluctuations. The only moving part is a piston that executes work, and the engine has purely electronic controls and it is free of the major weakness of the original Szilard engine in not requiring removal and repositioning the piston at the end of the cycle. For both devices, the energy dissipation in the memory and other binary informatics components are insignificant compared to the exponentially large energy dissipation in the analog part responsible for creating new information by measurement and decision. This result contradicts the view that the energy dissipation in the memory during erasure is the most essential dissipation process in a demon. Nevertheless the dissipation in the memory and information processing parts is sufficient to secure the Second Law of Thermodynamics.

Laboratory testing of ozone oxidation of Hanford Site waste from Tank 241-SY-101

International Nuclear Information System (INIS)

Delegard, C.H.; Stubbs, A.M.; Bolling, S.D.

1993-01-01

Ozone was investigated as a reagent to oxidize and destroy organic species present in simulated and genuine waste from Hanford Site Tank 241-SY-101 (Tank 101-SY). Two high-shear mixing apparatus were tested to perform the gas-to-solution mass transfer necessary to achieve efficient use of the ozone reagent. Oxidations of nitrite (to form nitrate) and organic species were observed. The organics oxidized to form carbonate and oxalate as well as nitrate and nitrogen gas from nitrogen associated with the organic. oxidations of metal species also were observed directly or inferred by solubilities. The chemical reaction stoichiometries were consistent with reduction of one oxygen atom per ozone molecule. Acetate, oxalate, and formate were found to comprise about 40% of the genuine waste's total organic carbon (TOC) concentration. Ozonation was found to be chemically feasible for destroying organic species (except oxalate) present in the wastes in Tank 101-SY. The simulated waste formulation used in these studies credibly modelled the ozonation behavior of the genuine waste

Acceptance test procedure, 241-SY-101/241-C-106 shot loading system

International Nuclear Information System (INIS)

Ostrom, M.J.

1994-01-01

This Acceptance Test Procedure is for the 241-SY-101/241-C-106 Shot Loading System. The procedure will test the components of the Shot Loading System and its capability of adequately loading shot into the annular space of the Container. The loaded shot will provide shielding as required for transporting and storage of a contaminated pump after removal from the tank. This test serves as verification that the SLS is acceptable for use in the pump removal operations for Tanks 241-SY-101, 241-C-106 and 241-AY-102. The pump removal operation for these three tanks will be performed by two different organizations with different equipment, but the Shot Loading System will be compatible between the two operations

A Case Study of Designing an E-learning Electrical Engineering Course

Directory of Open Access Journals (Sweden)

Sameer Hanna Khader

2012-08-01

Full Text Available Abstract: This paper presents a case study of designing an e-learning course in the field of electrical engineering- Industrial automation program at Palestine Polytechnic University. The applied methodology consisting of few stages starting with formulating the major course objectives, extracting topics outcomes, design the appropriate teaching tools and storyboard, and as final stage the evaluation system is designed. On other hand, an information communication technology (ICT questionnaire has been designed and targeting attended in the course students with purpose evaluating student ICT knowledge, knowledge leveling, and treatment their weaknesses. The designed topics are modified according to feedback evaluation obtained from students throughout designed for this purpose questionnaire. The observed weaknesses in course topics have been eliminated and finally the modified course was uploaded to the university e-learning platform. Electrical engineering core course with 300 level was carried out for department students, where the obtained results shows significant enhancement in teaching and learning performances of both course instructors and students.

The effects of heating and dilution on the rheological and physical properties of Tank 241-SY-101 waste

International Nuclear Information System (INIS)

Tingey, J.M.; Bredt, P.R.; Shade, E.H.

1994-10-01

Of the 177 high-level waste underground storage tanks at the Hanford Site, 25 have been identified as being potentially capable of generating and releasing flammable gas. Tank 241-SY-101 has exhibited periodic releases of gas, and in some cases the gas released has exceeded the lower flammable gas limit. The components of the released gas from Tank 241-SY-101 are hydrogen, nitrous oxide, nitrogen, ammonia, carbon monoxide, and methane. A mitigation strategy that may effectively reduce the retention and release of these gases and the release of flammable gases is dilution coupled with eating of the tank wastes. The purpose of this work was to determine changes in rheological and physical properties caused by heating and dilution of actual 241-SY-101 waste. In May and December 1991, following periodic gas releases, samples of the waste in Tank 241-SY-101 were obtained. Current work quantified the effects of heating coupled with NaOH dilution of a combination of waste samples from Tank 241-SY-101 characteristic of a non-convective layer. The experimental approach and results of this heating and dilution study on Tank 241-SY-101 waste samples are described in Sections 2 and 3, respectively. In Section 3.1, a discussion of the rheological properties of the waste as a function of shearing forces, volume percent dilution, and temperature is presented. In Section 3.2, the physical properties of the waste dilutions are described, including the densities of the slurry, filtered solids, and filtrate; the settling behavior; and the percent filtered solids in the composite sample and each of the composite dilutions. A brief discussion of the results and uncertainties is given is Section 3.3. The conclusions of this investigation are reported in Section 4

The Secretome of Bone Marrow and Wharton Jelly Derived Mesenchymal Stem Cells Induces Differentiation and Neurite Outgrowth in SH-SY5Y Cells

Directory of Open Access Journals (Sweden)

Ana O. Pires

2014-01-01

Full Text Available The goal of this study was to determine and compare the effects of the secretome of mesenchymal stem cells (MSCs isolated from human bone-marrow (BMSCs and the Wharton jelly surrounding the vein and arteries of the umbilical cord (human umbilical cord perivascular cells (HUCPVCs on the survival and differentiation of a human neuroblastoma cell line (SH-SY5Y. For this purpose, SH-SY5Y cells were differentiated with conditioned media (CM from the MSCs populations referred above. Retinoic acid cultured cells were used as control for neuronal differentiated SH-SY5Y cells. SH-SY5Y cells viability assessment revealed that the secretome of BMSCs and HUCPVCs, in the form of CM, was able to induce their survival. Moreover, immunocytochemical experiments showed that CM from both MSCs was capable of inducing neuronal differentiation of SH-SY5Y cells. Finally, neurite lengths assessment and quantitative real-time reverse-transcription polymerase chain reaction (RT-PCR analysis demonstrated that CM from BMSCs and HUCPVCs differently induced neurite outgrowth and mRNA levels of neuronal markers exhibited by SH-SY5Y cells. Overall, our results show that the secretome of both BMSCs and HUCPVCs was capable of supporting SH-SY5Y cells survival and promoting their differentiation towards a neuronal phenotype.

The Integration of Gasification Systems with Gas Engine to Produce Electrical Energy from Biomass

Science.gov (United States)

Siregar, K.; Alamsyah, R.; Ichwana; Sholihati; Tou, S. B.; Siregar, N. C.

2018-05-01

The need for energy especially biomass-based renewable energy continues to increase in Indonesia. The objective of this research was to design downdraft gasifier machine with high content of combustible gas on gas engine. Downdraft gasifier machine was adjusted with the synthetic gas produced from biomass. Besides that, the net energy ratio, net energy balance, renewable index, economic analysis, and impact assessment also been conducted. Gas engine that was designed in this research had been installed with capacity of 25 kW with diameter and height of reactor were 900 mm and 1000 mm respectively. The method used here were the design the Detailed Engineering Design (DED), assembly, and performance test of gas engine. The result showed that gas engine for biomass can be operated for 8 hours with performance engine of 84% and capacity of 25 kW. Net energy balance, net energy ratio, and renewable index was 30 MJ/kWh-electric; 0.89; 0.76 respectively. The value of GHG emission of Biomass Power Generation is 0.03 kg-CO2eq/MJ. Electrical production cost for Biomass Power Generation is about Rp.1.500,/kWh which is cheaper than Solar Power Generation which is about of Rp. 3.300,-/kWh.

Acceptance test procedure for SY Tank Farm replacement exhauster unit

Energy Technology Data Exchange (ETDEWEB)

Becken, G.W.

1994-12-16

The proper functioning of a new 241-SY Tank Farm replacement exhauster will be acceptance tested, to establish operability and to provide an operational baseline for the equipment. During this test, a verification of all of the alarm and control circuits associated with the exhaust, which provide operating controls and/or signals to local and remote alarm/annunciator panels, shall be performed. Test signals for sensors that provide alarms, warnings, and/or interlocks will be applied to verify that alarm, warning, and interlock setpoints are correct. Alarm and warning lights, controls, and local and remote readouts for the exhauster will be verified to be adequate for proper operation of the exhauster. Testing per this procedure shall be conducted in two phases. The first phase of testing, to verify alarm, warning, and interlock setpoints primarily, will be performed in the MO-566 Fab Shop. The second phase of testing, to verify proper operation and acceptable interface with other tank farm systems, will be conducted after the exhauster and all associated support and monitoring equipment have been installed in the SY Tank Farm. The exhauster, which is mounted on a skid and which will eventually be located in the SY tank farm, receives input signals from a variety of sensors mounted on the skid and associated equipment. These sensors provide information such as: exhauster system inlet vacuum pressure; prefilter and HEPA filter differential pressures; exhaust stack sampler status; exhaust fan status; system status (running/shut down); and radiation monitoring systems status. The output of these sensors is transmitted to the exhauster annunciator panel where the signals are displayed and monitored for out-of-specification conditions.

Protective Effect of Edaravone Against Aβ25-35-Induced Mitochondrial Oxidative Damage in SH-SY5Y Cells.

Science.gov (United States)

Zhang, G-L; Zhang, L; Guo, Y-Y; Ma, Z-L; Wang, H-Y; Li, T; Liu, J; Du, Y; Yao, L; Li, T-T; Du, J-M

2017-05-20

Amyloid-β (Aβ)-induced oxidative stress plays an important role in the pathogenesis of Alzheimer's disease (AD). Recent studies show that Aβ accumulation may lead to mitochondrial oxidative damage. In the present study, we investigated the protective effect of edaravone on mitochondrial damage in SH-SY5Y cells treated with Aβ25-35. SH-SY5Y cells were pre-treated with 20, 40 or 80 μM edaravone before treatment with 25 μM Aβ25-35. After 24h cell culture, cellular apoptosis, intracellular reactive oxygen species (ROS), mitochondrial membrane potential (ΔΨm), ATP levels and mitochondrial morphology were evaluated. SH-SY5Y cells exposed to Aβ25-35 had high levels of apoptosis and ROS; loss of ΔΨm, decreased ATP levels and presence of mitochondrial swelling. However, these effects were significantly inhibited by edaravone pre-treatment. These results indicate that edaravone prevents mitochondria oxidative damage caused by Aβ in SH-SY5Y cells, which suggests that it may have potential clinical application in AD therapy.

Short Chemical Ischemia Triggers Phosphorylation of eIF2α and Death of SH-SY5Y Cells but not Proteasome Stress and Heat Shock Protein Response in both SH-SY5Y and T98G Cells.

Science.gov (United States)

Klacanova, Katarina; Pilchova, Ivana; Klikova, Katarina; Racay, Peter

2016-04-01

Both translation arrest and proteasome stress associated with accumulation of ubiquitin-conjugated protein aggregates were considered as a cause of delayed neuronal death after transient global brain ischemia; however, exact mechanisms as well as possible relationships are not fully understood. The aim of this study was to compare the effect of chemical ischemia and proteasome stress on cellular stress responses and viability of neuroblastoma SH-SY5Y and glioblastoma T98G cells. Chemical ischemia was induced by transient treatment of the cells with sodium azide in combination with 2-deoxyglucose. Proteasome stress was induced by treatment of the cells with bortezomib. Treatment of SH-SY5Y cells with sodium azide/2-deoxyglucose for 15 min was associated with cell death observed 24 h after treatment, while glioblastoma T98G cells were resistant to the same treatment. Treatment of both SH-SY5Y and T98G cells with bortezomib was associated with cell death, accumulation of ubiquitin-conjugated proteins, and increased expression of Hsp70. These typical cellular responses to proteasome stress, observed also after transient global brain ischemia, were not observed after chemical ischemia. Finally, chemical ischemia, but not proteasome stress, was in SH-SY5Y cells associated with increased phosphorylation of eIF2α, another typical cellular response triggered after transient global brain ischemia. Our results showed that short chemical ischemia of SH-SY5Y cells is not sufficient to induce both proteasome stress associated with accumulation of ubiquitin-conjugated proteins and stress response at the level of heat shock proteins despite induction of cell death and eIF2α phosphorylation.

Syömishäiriökuntoutujien hoitopolku : Peruskouluikäisten psykofyysinen fysioterapia Tampereen kaupungilla

OpenAIRE

Mäenrinta, Ellen

2015-01-01

Syömishäiriöt ovat yleisiä nuorten psykiatrisia sairauksia ja useimmiten uhkaavat nuoren normaalia kehitystä. Fysioterapia voi kuulua syömishäiriötä sairastava lapsen tai nuoren hoitoon jo heti alusta alkaen yhteistyössä moniammatillisen tiimin kanssa. Fysioterapia toteutetaan psykofyysisestä näkökulmasta yksilön omien tarpeiden ja tavoitteiden mukaisesti. Fysioterapiassa käsitellään muun muassa sairastuneen vääristyneitä kokemuksia omasta kehostaan, kielteistä suhtautumista omaan ulkonäkööns...

Ortoreksia : Oppitunti syömishäiriöistä yläkoulun 9.-luokkalaisille

OpenAIRE

Suvanto, Minna; Tanninen, Milla

2015-01-01

Elinympäristömme luo ihmisille helposti monenlaisia paineita. Sekä kauneudelle että terveydelle kuin ulkonäöllekin on luotu tietynlaiset ihanteet ja esikuvia on tarjolla paljon kaikenikäisille. Samalla ravitsemussuositukset muuttuvat jatkuvasti vallitsevan ajan myötä. Syömishäiriöt ovat käsitteenä melko yleisiä. Tunnetuimmat niistä ovat anoreksia, bulimia ja BED. Tämä opinnäytetyö käsittelee kyseisten syömishäiriöiden peruspiirteitä, etiologiaa ja parantumisvaiheita. Varsinaiseksi aiheeks...

Historical trends in tank 241-SY-101 waste temperatures and levels

International Nuclear Information System (INIS)

Antoniak, Z.I.

1993-09-01

The gas release and fluctuating level of the waste in tank 241-SY-101 have prompted more detailed interest in its historical behavior, in hopes of achieving a better understanding of its current status. To examine the historical behavior, essentially all of the tank waste temperature and level data record has been retrieved, examined, and plotted in various ways. To aid in interpreting the data, the depth of the non-convective waste layer was estimated by using a least-squares Chebyshev approximation to the temperatures. This report documents the retrieval critical examination, and graphic presentation of 241-SY-101 temperature and waste level histories. The graphic presentations clearly indicate a tank cooling trend that has become precipitous since late 1991. The plots also clearly show the decreasing frequency of waste gas release events, increasing height of the non-convective layer, and larger level drops per event

Alternatives to electrical cogeneration: The direct application of steam engines

International Nuclear Information System (INIS)

Phillips, W.C.

1993-01-01

Although small to medium sized industrial facilities are aware of electrical cogeneration, often they are too small for it to be economically justifiable. The direct application of steam turbine power to equipment formerly powered by electric motors, can allow them to use steam capacity to reduce electrical demand and consumption, bypassing cogeneration. Cogeneration converts the heat energy of steam into circular mechanical motion and then converts the circular mechanical motion into electricity. Each conversion entails a loss of energy due to friction and other conversion losses. A substantial amount of the generated electricity is then converted back into circular motion with electric motors, again incurring energy losses. Directly applying the mechanical motion of turbines eliminates both the motion-to-electricity (generator) and the electricity-to-motion (motor) conversion losses. Excess steam capacity during the summer is not unusual for facilities that use steam to provide winter heating. Similarly, most of these facilities experience a large electrical demand peak during the cooling season due to the electricity needed to operate centrifugal chillers. Steam capacity via a turbine to power the chillers can allow the boilers to operate at a higher loading while reducing electrical consumption and demand precisely those periods when demand reduction is most needed. In facilities where the steam generating capacity is sufficient, air compressors provide an appropriate year-round application for turbine power. This paper is the result of an on-going project by the Energy Division, State of North Carolina, Department of Economic and Community Development, in conjunction with the University of North Carolina at Charlotte. The objective of this project is to educate the operating engineers and managers of small to medium sized manufacturing facilities on the technical application and economic justification of steam turbine power

SyPRID sampler: A large-volume, high-resolution, autonomous, deep-ocean precision plankton sampling system

Science.gov (United States)

Billings, Andrew; Kaiser, Carl; Young, Craig M.; Hiebert, Laurel S.; Cole, Eli; Wagner, Jamie K. S.; Van Dover, Cindy Lee

2017-03-01

The current standard for large-volume (thousands of cubic meters) zooplankton sampling in the deep sea is the MOCNESS, a system of multiple opening-closing nets, typically lowered to within 50 m of the seabed and towed obliquely to the surface to obtain low-spatial-resolution samples that integrate across 10 s of meters of water depth. The SyPRID (Sentry Precision Robotic Impeller Driven) sampler is an innovative, deep-rated (6000 m) plankton sampler that partners with the Sentry Autonomous Underwater Vehicle (AUV) to obtain paired, large-volume plankton samples at specified depths and survey lines to within 1.5 m of the seabed and with simultaneous collection of sensor data. SyPRID uses a perforated Ultra-High-Molecular-Weight (UHMW) plastic tube to support a fine mesh net within an outer carbon composite tube (tube-within-a-tube design), with an axial flow pump located aft of the capture filter. The pump facilitates flow through the system and reduces or possibly eliminates the bow wave at the mouth opening. The cod end, a hollow truncated cone, is also made of UHMW plastic and includes a collection volume designed to provide an area where zooplankton can collect, out of the high flow region. SyPRID attaches as a saddle-pack to the Sentry vehicle. Sentry itself is configured with a flight control system that enables autonomous survey paths to low altitudes. In its verification deployment at the Blake Ridge Seep (2160 m) on the US Atlantic Margin, SyPRID was operated for 6 h at an altitude of 5 m. It recovered plankton samples, including delicate living larvae, from the near-bottom stratum that is seldom sampled by a typical MOCNESS tow. The prototype SyPRID and its next generations will enable studies of plankton or other particulate distributions associated with localized physico-chemical strata in the water column or above patchy habitats on the seafloor.

Acquisition and reduction of data obtained from Tank 101-SY in-situ ball rheometer

International Nuclear Information System (INIS)

Shepard, C.L.; Chieda, M.A.; Kirihara, L.J.

1994-12-01

Development of the ball rheometer to measure rheological properties and density of the waste in Hanford Tank 241-SY-101 will be completed around September 1994. Since the ball rheometer project began, a mixer pump has been installed in this tank, and by all accounts this pump has been very successful at mitigating the flammable gas problem associated with Tank 101-SY. Present plans now call for the use of mixer pumps in several other tanks. The ball rheometer will serve as a diagnostic tool for judging the effectiveness of mixing in Tank 101-SY and others and will be one of few in-situ probes available for diagnostic measurements. The in-situ data collection strategy and the methods of data analysis and reduction are presented in this final report concerning this instrument. It is believed that a generalized Bingham fluid model (Herschel-Bulkley fluid model) may be useful for describing at least some of the waste contained in Tank 101-SY, and data obtained in the tank will initially be reduced using this fluid model. The single largest uncertainty in the determination of the drag force on the ball is the drag force which will be experienced by the cable attached to the ball. This drag can be a substantial fraction of the total drag when the ball is deep within the tank. Careful accounting of the cable drag will be important in the reduction of the data. The data collection strategy allows the determination of the waste fluid rheology both in the undisturbed state and after it has been disturbed by the ball. Fluid density will be measured at regular intervals

Transport of Tank 241-SY-101 Waste Slurry: Effects of Dilution and Temperature on Critical Pipeline Velocity

International Nuclear Information System (INIS)

KP Recknagle; Y Onishi

1999-01-01

This report presents the methods and results of calculations performed to predict the critical velocity and pressure drop required for the two-inch pipeline transfer of solid/liquid waste slurry from underground waste storage Tank 241-SY-101 to Tank 241-SY- 102 at the Hanford Site. The effects of temperature and dilution on the critical velocity were included in the analysis. These analyses show that Tank 241-SY-101 slurry should be diluted with water prior to delivery to Tank 241-SY-102. A dilution ratio of 1:1 is desirable and would allow the waste to be delivered at a critical velocity of 1.5 ft/sec. The system will be operated at a flow velocity of 6 ft/sec or greater therefore, this velocity will be sufficient to maintain a stable slurry delivery through the pipeline. The effect of temperature on the critical velocity is not a limiting factor when the slurry is diluted 1:1 with water. Pressure drop at the critical velocity would be approximately two feet for a 125-ft pipeline (or 250-ft equivalent straight pipeline). At 6 ft/sec, the pressure drop would be 20 feet over a 250-ft equivalent straight pipeline

Neuroprotective Effects of Germinated Brown Rice against Hydrogen Peroxide Induced Cell Death in Human SH-SY5Y Cells

Directory of Open Access Journals (Sweden)

Shahid Iqbal

2012-08-01

Full Text Available The neuroprotective and antioxidative effects of germinated brown rice (GBR, brown rice (BR and commercially available γ-aminobutyric acid (GABA against cell death induced by hydrogen peroxide (H₂O₂ in human neuroblastoma SH-SY5Y cells have been investigated. Results show that GBR suppressed H₂O₂-mediated cytotoxicity and induced G0/G1 phase cell cycle arrest in SH-SY5Y cells. Moreover, GBR reduced mitochondrial membrane potential (MMP and prevented phosphatidylserine (PS translocation in SH-SY5Y cells, key features of apoptosis, and subsequent cell death. GBR exhibited better neuroprotective and antioxidative activities as compared to BR and GABA. These results indicate that GBR possesses high antioxidative activities and suppressed cell death in SH-SY5Y cells by blocking the cell cycle re-entry and apoptotic mechanisms. Therefore, GBR could be developed as a value added functional food to prevent neurodegenerative diseases caused by oxidative stress and apoptosis.

A Route for Polymer Nanocomposites with Engineered Electrical Conductivity and Percolation Threshold

Directory of Open Access Journals (Sweden)

Lawrence T. Drzal

2010-02-01

Full Text Available Polymer nanocomposites with engineered electrical properties can be made by tuning the fabrication method, processing conditions and filler’s geometric and physical properties. This work focuses on investigating the effect of filler’s geometry (aspect ratio and shape, intrinsic electrical conductivity, alignment and dispersion within the polymer, and polymer crystallinity, on the percolation threshold and electrical conductivity of polypropylene based nanocomposites. The conductive reinforcements used are exfoliated graphite nanoplatelets, carbon black, vapor grown carbon fibers and polyacrylonitrile carbon fibers. The composites are made using melt mixing followed by injection molding. A coating method is also employed to improve the nanofiller’s dispersion within the polymer and compression molding is used to alter the nanofiller’s alignment.

Active and Collaborative Learning in an Introductory Electrical and Computer Engineering Course

Science.gov (United States)

Kotru, Sushma; Burkett, Susan L.; Jackson, David Jeff

2010-01-01

Active and collaborative learning instruments were introduced into an introductory electrical and computer engineering course. These instruments were designed to assess specific learning objectives and program outcomes. Results show that students developed an understanding comparable to that of more advanced students assessed later in the…

The Syed temporary interstitial iridium gynaecological implant: an inverse planning system

International Nuclear Information System (INIS)

Fung, Albert Y.C.

2002-01-01

Patients with advanced gynaecological cancer are often treated with a temporary interstitial implant using the Syed template and Ir-192 ribbons at the Memorial Sloan-Kettering Cancer Center. Urgency in planning is great. We created a computerized inverse planning system for the Syed temporary gynaecological implant, which optimized the ribbon strengths a few seconds after catheter digitization. Inverse planning was achieved with simulated annealing. We discovered that hand-drawn target volumes had drawbacks; hence instead of producing a grid of points based on target volume, the optimization points were generated directly from the catheter positions without requiring an explicit target volume. Since all seeds in the same ribbon had the same strength, the minimum doses were located at both ends of the implant. Optimization points generated at both ends ensured coverage of the whole implant. Inverse planning took only a few seconds, and generated plans that provide a good starting point for manual improvement. (author)

Progress of the Computer-Aided Engineering of Electric Drive Vehicle Batteries (CAEBAT) (Presentation)

Energy Technology Data Exchange (ETDEWEB)

Pesaran, A. A.; Han, T.; Hartridge, S.; Shaffer, C.; Kim, G. H.; Pannala, S.

2013-06-01

This presentation, Progress of Computer-Aided Engineering of Electric Drive Vehicle Batteries (CAEBAT) is about simulation and computer-aided engineering (CAE) tools that are widely used to speed up the research and development cycle and reduce the number of build-and-break steps, particularly in the automotive industry. Realizing this, DOE?s Vehicle Technologies Program initiated the CAEBAT project in April 2010 to develop a suite of software tools for designing batteries.

Electrically conductive ceramics and new joining technology for applications in HTR engineering

International Nuclear Information System (INIS)

Hille, Carmen; Lippmann, Wolfgang; Hurtado, Antonio

2012-01-01

Ceramic constructional components are quite extensively required for operation of high-temperature nuclear reactors. Functional ceramics, in addition to constructional ceramics, are increasingly coming into the focus of research. Ceramic materials are predestined for use at high temperatures and in corrosive atmospheres. Modification of silicon carbide (SiC) by targeted doping, for instance, produces a suitable material for the production of heating conductors and thermoelectric generators. As a construction material, silicon carbide (SiC) is especially interesting due to its very good thermal, mechanical and radiological properties. SiC, furthermore, performs well when activated by neutron irradiation, with the induced activation subsiding after only a few hours (). This property vector makes it an ideal starting material for use in a wide range of functional elements in high-temperature power engineering, particularly in high-temperature nuclear reactor engineering (e.g. V/HTR) including thermochemical plants for hydrogen generation or Synfuel production. In principle, it is possible to produce all-ceramic assemblies consisting of a thermoelectric generator and a sensor that can provide reliable measurement signals under extreme conditions in the high-temperature range without external power supply. This paper explains the feasibility of laser-joining such modified non-oxide ceramics, how to make electrically conductive joints, and thus, how to design complex assemblies. The parameters required for an optimal laser process to join ceramic materials were determined in extensive preliminary experiments. These investigations focused on the specific electrical resistances and optical properties. Specifically developed brazing fillers were fine-tuned so that the joints of the ceramics improved in terms of their physical interactions, chemical reactions and ability to bond or key chemically and mechanically with the ceramic surfaces. Thereby, the electrical

Electrically conductive ceramics and new joining technology for applications in HTR engineering

Energy Technology Data Exchange (ETDEWEB)

Hille, Carmen, E-mail: carmen.hille@ilkdresden.de [Dresden University of Technology (TU Dresden), Institute of Power Engineering, Chair of Hydrogen Technology and Nuclear Power Engineering, George-Baehr-Str. 3b, D-01062 Dresden (Germany); Lippmann, Wolfgang, E-mail: wolfgang.lippmann@tu-dresden.de [Dresden University of Technology (TU Dresden), Institute of Power Engineering, Chair of Hydrogen Technology and Nuclear Power Engineering, George-Baehr-Str. 3b, D-01062 Dresden (Germany); Hurtado, Antonio, E-mail: antonio.hurtado@tu-dresden.de [Dresden University of Technology (TU Dresden), Institute of Power Engineering, Chair of Hydrogen Technology and Nuclear Power Engineering, George-Baehr-Str. 3b, D-01062 Dresden (Germany)

2012-10-15

Ceramic constructional components are quite extensively required for operation of high-temperature nuclear reactors. Functional ceramics, in addition to constructional ceramics, are increasingly coming into the focus of research. Ceramic materials are predestined for use at high temperatures and in corrosive atmospheres. Modification of silicon carbide (SiC) by targeted doping, for instance, produces a suitable material for the production of heating conductors and thermoelectric generators. As a construction material, silicon carbide (SiC) is especially interesting due to its very good thermal, mechanical and radiological properties. SiC, furthermore, performs well when activated by neutron irradiation, with the induced activation subsiding after only a few hours (). This property vector makes it an ideal starting material for use in a wide range of functional elements in high-temperature power engineering, particularly in high-temperature nuclear reactor engineering (e.g. V/HTR) including thermochemical plants for hydrogen generation or Synfuel production. In principle, it is possible to produce all-ceramic assemblies consisting of a thermoelectric generator and a sensor that can provide reliable measurement signals under extreme conditions in the high-temperature range without external power supply. This paper explains the feasibility of laser-joining such modified non-oxide ceramics, how to make electrically conductive joints, and thus, how to design complex assemblies. The parameters required for an optimal laser process to join ceramic materials were determined in extensive preliminary experiments. These investigations focused on the specific electrical resistances and optical properties. Specifically developed brazing fillers were fine-tuned so that the joints of the ceramics improved in terms of their physical interactions, chemical reactions and ability to bond or key chemically and mechanically with the ceramic surfaces. Thereby, the electrical

Teaching Complicated Conceptual Knowledge with Simulation Videos in Foundational Electrical Engineering Courses

Science.gov (United States)

Chen, Baiyun; Wei, Lei; Li, Huihui

2016-01-01

Building a solid foundation of conceptual knowledge is critical for students in electrical engineering. This mixed-method case study explores the use of simulation videos to illustrate complicated conceptual knowledge in foundational communications and signal processing courses. Students found these videos to be very useful for establishing…

Mathematics for electric engineers. Complex numbers; Mathematiques pour l`electricien. Nombres complexes

Energy Technology Data Exchange (ETDEWEB)

Rouxel, C. [Conservatoire National des Arts et Metiers (CNAM), 75 - Paris (France)

1999-05-01

Complex numbers are widely used in electrical engineering. This article is divided into 5 parts dealing successively with: the cartesian form of complex numbers (definition, conjugated complex numbers, graphical representation); the trigonometrical form of complex numbers (module and argument, trigonometrical form, exponential notation, multiplication and division of two complex numbers); Moivre and Euler formulae; applications (square root and second degree equation, n. roots, plan rotation and similarity); cissoidal transformation (definition, properties, applications to electricity: complex impedance in permanent sinusoidal regime, transfer function of a linear system in permanent regime, study of an example). (J.S.)

Characterization of the novel dimethyl sulfide-degrading bacterium Alcaligenes sp. SY1 and its biochemical degradation pathway

Energy Technology Data Exchange (ETDEWEB)

Sun, Yiming; Qiu, Jiguo; Chen, Dongzhi; Ye, Jiexu; Chen, Jianmeng, E-mail: jchen@zjut.edu.cn

2016-03-05

Highlights: • A novel efficient DMS-degrading bacterium Alcaligenes sp. SY1 was identified. • A RSM was applied to optimize incubation condition of Alcaligenes sp. SY1. • SIP was applied as C{sup 13} labelled DMS to trace intermediates during DMS degradation. • Kinetics of DMS degradation via batch experiment was revealed. • Carbon and sulfur balance were analyzed during DMS degradation process. - Abstract: Recently, the biodegradation of volatile organic sulfur compounds (VOSCs) has become a burgeoning field, with a growing focus on the reduction of VOSCs. The reduction of VOSCs encompasses both organic emission control and odor control. Herein, Alcaligenes sp. SY1 was isolated from active sludge and found to utilize dimethyl sulfide (DMS) as a growth substrate in a mineral salt medium. Response surface methodology (RSM) analysis was applied to optimize the incubation conditions. The following conditions for optimal degradation were identified: temperature 27.03 °C; pH 7.80; inoculum salinity 0.84%; and initial DMS concentration 1585.39 μM. Under these conditions, approximately 99% of the DMS was degraded within 30 h of incubation. Two metabolic compounds were detected and identified by gas chromatography–mass spectrometry (GC–MS): dimethyl disulfide (DMDS) and dimethyl trisulfide (DMTS). The DMS degradation kinetics for different concentrations were evaluated using the Haldane–Andrews model and the pseudo first-order model. The maximum specific growth rate and degradation rate of Alcaligenes sp. SY1 were 0.17 h{sup −1} and 0.63 gs gx{sup −1} h{sup −1}. A possible degradation pathway is proposed, and the results suggest that Alcaligenes sp. SY1 has the potential to control odor emissions under aerobic conditions.

Electrically polarized PLLA nanofibers as neural tissue engineering scaffolds with improved neuritogenesis.

Science.gov (United States)

Barroca, Nathalie; Marote, Ana; Vieira, Sandra I; Almeida, Abílio; Fernandes, Maria H V; Vilarinho, Paula M; da Cruz E Silva, Odete A B

2018-07-01

Tissue engineering is evolving towards the production of smart platforms exhibiting stimulatory cues to guide tissue regeneration. This work explores the benefits of electrical polarization to produce more efficient neural tissue engineering platforms. Poly (l-lactic) acid (PLLA)-based scaffolds were prepared as solvent cast films and electrospun aligned nanofibers, and electrically polarized by an in-lab built corona poling device. The characterization of the platforms by thermally stimulated depolarization currents reveals a polarization of 60 × 10 -10 C cm -2 that is stable on poled electrospun nanofibers for up to 6 months. Further in vitro studies using neuroblastoma cells reveals that platforms' polarization potentiates Retinoic Acid-induced neuronal differentiation. Additionally, in differentiating embryonic cortical neurons, poled aligned nanofibers further increased neurite outgrowth by 30% (+70 μm) over non-poled aligned nanofibers, and by 50% (+100 μm) over control conditions. Therefore, the synergy of topographical cues and electrical polarization of poled aligned nanofibers places them as promising biocompatible and bioactive platforms for neural tissue regeneration. Given their long lasting induced polarization, these PLLA poled nanofibrous scaffolds can be envisaged as therapeutic devices of long shelf life for neural repair applications. Copyright © 2018 Elsevier B.V. All rights reserved.

Engineering electrodynamics electric machine, transformer, and power equipment design

CERN Document Server

Turowski, Janusz

2013-01-01

Due to a huge concentration of electromagnetic fields and eddy currents, large power equipment and systems are prone to crushing forces, overheating, and overloading. Luckily, power failures due to disturbances like these can be predicted and/or prevented.Based on the success of internationally acclaimed computer programs, such as the authors' own RNM-3D, Engineering Electrodynamics: Electric Machine, Transformer, and Power Equipment Design explains how to implement industry-proven modeling and design techniques to solve complex electromagnetic phenomena. Considering recent progress in magneti

Acceptance test report for the 241-SY-101 Flexible Receiver Gamma Detector System

International Nuclear Information System (INIS)

Dowell, J.L.

1995-01-01

This Acceptance Test Report is for the 241-SY-101 Flexible Receiver Gamma Detector System. This test verified that the data logger and data converter for the gamma detector system functions as intended

Fire protection electrical engineering

International Nuclear Information System (INIS)

Oh, Jung Min

2000-03-01

This book concentrates of electricity with current, voltage, power, ohms law, access of resistance, electrolytic analysis and battery, static on frictional electricity and electrostatic induction, coulomb's law, Gauss's law, condenser and capacity, magmatism on magnetic field and magnetic line of force, magnetic circuit, electromagnetic force, electromotive current, basic alternating current circuit, circuit network analysis, three-phase current, non-sinusoidal alternating current, transient phenomena, semiconductor, electric measurement on measurement over resistance, power, power rate and circuit tester, automatic control on introduction, term, classification, foundation of sequence control, logic circuit and basic logic circuit and electric equipment.

Equivalent electrical network model approach applied to a double acting low temperature differential Stirling engine

International Nuclear Information System (INIS)

Formosa, Fabien; Badel, Adrien; Lottin, Jacques

2014-01-01

Highlights: • An equivalent electrical network modeling of Stirling engine is proposed. • This model is applied to a membrane low temperate double acting Stirling engine. • The operating conditions (self-startup and steady state behavior) are defined. • An experimental engine is presented and tested. • The model is validated against experimental results. - Abstract: This work presents a network model to simulate the periodic behavior of a double acting free piston type Stirling engine. Each component of the engine is considered independently and its equivalent electrical circuit derived. When assembled in a global electrical network, a global model of the engine is established. Its steady behavior can be obtained by the analysis of the transfer function for one phase from the piston to the expansion chamber. It is then possible to simulate the dynamic (steady state stroke and operation frequency) as well as the thermodynamic performances (output power and efficiency) for given mean pressure, heat source and heat sink temperatures. The motion amplitude especially can be determined by the spring-mass properties of the moving parts and the main nonlinear effects which are taken into account in the model. The thermodynamic features of the model have then been validated using the classical isothermal Schmidt analysis for a given stroke. A three-phase low temperature differential double acting free membrane architecture has been built and tested. The experimental results are compared with the model and a satisfactory agreement is obtained. The stroke and operating frequency are predicted with less than 2% error whereas the output power discrepancy is of about 30%. Finally, some optimization routes are suggested to improve the design and maximize the performances aiming at waste heat recovery applications

Oil Coking Prevention Using Electric Water Pump for Turbo-Charge Spark-Ignition Engines

Directory of Open Access Journals (Sweden)

Han-Ching Lin

2014-01-01

Full Text Available Turbocharger has been widely implemented for internal combustion engine to increase an engine's power output and reduce fuel consumption. However, its operating temperature would rise to 340°C when engine stalls. This higher temperature may results in bearing wear, run-out, and stick, due to oil coking and insufficient lubrication. In order to overcome these problems, this paper employs Electric Water Pump (EWP to supply cool liquid to turbocharger actively when the engine stalls. The system layout, operating timing, and duration of EWP are investigated for obtaining optimal performance. The primarily experimental results show that the proposed layout and control strategy have a lower temperature of 100°C than the conventional temperature 225°C.

A Model for the Development of a CDIO Based Curriculum in Electrical Engineering

DEFF Research Database (Denmark)

Bruun, Erik; Kjærgaard, Claus

2011-01-01

This paper deals with a model providing a structured method for engineering curriculum design. The model is developed to show the major influencers on the curriculum design and the relations between the influencers. These influencers are identified as the engineering science, the business...... environment, the university environment, and the teachers and students. Each of them and their influence on the curriculum is described and the sources of information about the influencers are discussed. The CDIO syllabus has been defined as part of the basis for the Bachelor of Engineering programs...... at the Technical University of Denmark and this gives a strong direct impact of the university environment on the resulting curriculum in electrical engineering. The resulting Bachelor of Engineering curriculum is presented and it is discussed how it complies with the model for curriculum development. The main...

MacSyFinder: a program to mine genomes for molecular systems with an application to CRISPR-Cas systems.

Directory of Open Access Journals (Sweden)

Sophie S Abby

Full Text Available Biologists often wish to use their knowledge on a few experimental models of a given molecular system to identify homologs in genomic data. We developed a generic tool for this purpose.Macromolecular System Finder (MacSyFinder provides a flexible framework to model the properties of molecular systems (cellular machinery or pathway including their components, evolutionary associations with other systems and genetic architecture. Modelled features also include functional analogs, and the multiple uses of a same component by different systems. Models are used to search for molecular systems in complete genomes or in unstructured data like metagenomes. The components of the systems are searched by sequence similarity using Hidden Markov model (HMM protein profiles. The assignment of hits to a given system is decided based on compliance with the content and organization of the system model. A graphical interface, MacSyView, facilitates the analysis of the results by showing overviews of component content and genomic context. To exemplify the use of MacSyFinder we built models to detect and class CRISPR-Cas systems following a previously established classification. We show that MacSyFinder allows to easily define an accurate "Cas-finder" using publicly available protein profiles.MacSyFinder is a standalone application implemented in Python. It requires Python 2.7, Hmmer and makeblastdb (version 2.2.28 or higher. It is freely available with its source code under a GPLv3 license at https://github.com/gem-pasteur/macsyfinder. It is compatible with all platforms supporting Python and Hmmer/makeblastdb. The "Cas-finder" (models and HMM profiles is distributed as a compressed tarball archive as Supporting Information.

Stirling engines for low-temperature solar-thermal-electric power generation

Science.gov (United States)

der Minassians, Artin

This dissertation discusses the design and development of a distributed solar-thermal-electric power generation system that combines solar-thermal technology with a moderate-temperature Stirling engine to generate electricity. The conceived system incorporates low-cost materials and utilizes simple manufacturing processes. This technology is expected to achieve manufacturing cost of less than $1/W. Since solar-thermal technology is mature, the analysis, design, and experimental assessment of moderate-temperature Stirling engines is the main focus of this thesis. The design, fabrication, and test of a single-phase free-piston Stirling engine prototype is discussed. This low-power prototype is designed and fabricated as a test rig to provide a clear understanding of the Stirling cycle operation, to identify the key components and the major causes of irreversibility, and to verify corresponding theoretical models. As a component, the design of a very low-loss resonant displacer piston subsystem is discussed. The displacer piston is part of a magnetic circuit that provides both a required stiffness and actuation forces. The stillness is provided by a magnetic spring, which incorporates an array of permanent magnets and has a very linear stiffness characteristic that facilitates the frequency tuning. In this prototype, the power piston is not mechanically linked to the displacer piston and forms a mass-spring resonating subsystem with the engine chamber gas spring and has resonant frequency matched to that of the displacer. The fabricated engine prototype is successfully tested and the experimental results are presented and discussed. Extensive experimentation on individual component subsystems confirms the theoretical models and design considerations, providing a sound basis for higher power Stirling engine designs for residential or commercial deployments. Multi-phase Stirling engine systems are also considered and analyzed. The modal analysis of these machines proves

Electricity Theory

International Nuclear Information System (INIS)

Gong, Ha Soung

2006-12-01

The text book composed of five parts, which are summary of this book, arrangement of electricity theory including electricity nad magnetism, a direct current, and alternating current. It has two dictionary electricity terms for a synonym. The last is an appendix. It is for preparing for test of officer, electricity engineer and fire fighting engineer.

SCEE 2008 book of abstracts. The 7. international conference on scientific computing in electrical engineering (SCEE 2008)

Energy Technology Data Exchange (ETDEWEB)

Roos, J.; Costa, L.R.J. (ed.)

2008-09-15

SCEE is an international conference series dedicated to Scientific Computing in Electrical Engineering. The 7th International Conference on Scientific Computing in Electrical Engineering (SCEE 2008) in Espoo, Finland, is organized by the Helsinki University of Technology (TKK); Faculty of Electronics, Communications and Automation (ECA); Department of Radio Science and Engineering (RAD); Circuit Theory Group. (SCEE 2008 web site: http://www.ct.tkk.fi/scee2008/). The aim of the SCEE 2008 conference is to bring together scientists from academia and industry with the goal of intensive discussions on modeling and numerical simulation of electronic circuits and of electromagnetic fields. The conference is mainly directed towards mathematicians and electrical engineers. The SCEE 2008 conference has the following four main topics: 1. Computational Electromagnetics (CE), 2. Circuit Simulation (CS), 3. Coupled Problems (CP), 4. Mathematical and Computational Methods (CM). The selection of abstracts in this book was carried out by the Program Committee; each abstract was reviewed by two or three reviewers. The authors of all accepted abstracts were invited to submit an extended full paper, which will be reviewed as well. The accepted full papers will later on be published in a separate post-conference book

241-SY Double Shell Tanks (DST) Integrity Assessment Report

International Nuclear Information System (INIS)

JENSEN, C.E.

1999-01-01

This report presents the results of the integrity assessment of the 241-SY double-shell tank farm facility located in the 200 West Area of the Hanford Site. The assessment included the design evaluation and integrity examinations of the tanks and concluded that the facility is adequately designed, is compatible with the waste, and is fit for use. Recommendations including subsequent examinations, are made to ensure the continued safe operation of the tanks

Effort to increase an engine performance using electrical ignition system for motor vehicle

Directory of Open Access Journals (Sweden)

I Wayan Bandem Adnyana

2012-11-01

Full Text Available Increasing engine performances using electrical ignition system on motor vehicle. In accordance with the development oftechnology, improvisation of automotive is created in order to increase the performance of engine. The method to increase thisperformance has been done by modify the ignition system, where the conventional method of ignition system which uses contactbreaker substituted by using capacitor. The improvisation of ignition system has been tested by increasing the speed and load onstationary condition. Results show that the improvisation of ignition system by using capacitor increases the effective power andreduce the specific fuel consumption of engine and reduce the gas emission of CO.

Antihypoxic effect of miR-24 in SH-SY5Y cells under hypoxia via downregulating expression of neurocan

Energy Technology Data Exchange (ETDEWEB)

Sun, Xingyuan, E-mail: sunxingyuan@sina.com; Ren, Zhanjun; Pan, Yunzhi; Zhang, Chenxin

2016-09-02

Hypoxia-induced apoptosis-related mechanisms involved in the brain damage following cerebral ischemia injury. A subset of the small noncoding microRNA (miRNAs) is regulated by tissue oxygen levels, and miR-24 was found to be activated by hypoxic conditions. However, the roles of miR-24 and its target gene in neuron are not well understood. Here, we validated miRNA-24 is down-regulated in patients with cerebral infarction. Hypoxia suppressed the expression of miR-24, but increased the expression of neurocan in both mRNA and protein levels in SH-SY5Y cells. MiR-24 mimics reduced the expression of neurocan, suppressed cell apoptosis, induced cell cycle progression and cell proliferation in SH-SY5Y cells under hypoxia. By luciferase reporter assay, neurocan is validated a direct target gene of miR-24. Furthermore, knockdown of neurocan suppressed cell apoptosis, induced cell cycle progression and cell proliferation in SH-SY5Y cells under hypoxia. Taken together, miR-24 overexpression or silencing of neurocan shows an antihypoxic effect in SH-SY5Y cells. Therefore, miR-24 and neurocan play critical roles in neuron cell apoptosis and are potential therapeutic targets for ischemic brain disease. - Highlights: • miR-24 and neurocan play critical roles in neuron cell apoptosis. • miR-24 and neurocan are potential therapeutic targets for ischemic brain disease. • Antihypoxic effect of miR-24 and neurocan in SH-SY5Y cells.

Salicin from Willow Bark can Modulate Neurite Outgrowth in Human Neuroblastoma SH-SY5Y Cells.

Science.gov (United States)

Wölfle, Ute; Haarhaus, Birgit; Kersten, Astrid; Fiebich, Bernd; Hug, Martin J; Schempp, Christoph M

2015-10-01

Salicin from willow bark has been used throughout centuries in China and Europe for the treatment of pain, headache, and inflammatory conditions. Recently, it could be demonstrated that salicin binds and activates the bitter taste receptor TAS2R16. Studies on rodent tissues showed the general expression of bitter taste receptors (TAS2Rs) in rodent brain. Here, we demonstrate the expression of hTAS2R16 in human neuronal tissues and the neuroblastoma cell line SH-SY5Y. The functionality was analyzed in the neuroblastoma cell line SH-SY5Y after stimulation with salicin, a known TAS2R16 agonist. In this setting salicin induced in SH-SY5Y cells phosphorylation of ERK and CREB, the key transcription factor of neuronal differentiation. PD98059, an inhibitor of the ERK pathway, as well as probenecid, a TAS2R16 antagonist, inhibited receptor phosphorylation as well as neurite outgrowth. These data show that salicin might modulate neurite outgrowth by bitter taste receptor activation. Copyright © 2015 John Wiley & Sons, Ltd.

Identification and classification of genes regulated by phosphatidylinositol 3-kinase- and TRKB-mediated signalling pathways during neuronal differentiation in two subtypes of the human neuroblastoma cell line SH-SY5Y.

Science.gov (United States)

Nishida, Yuichiro; Adati, Naoki; Ozawa, Ritsuko; Maeda, Aasami; Sakaki, Yoshiyuki; Takeda, Tadayuki

2008-10-28

SH-SY5Y cells exhibit a neuronal phenotype when treated with all-trans retinoic acid (RA), but the molecular mechanism of activation in the signalling pathway mediated by phosphatidylinositol 3-kinase (PI3K) is unclear. To investigate this mechanism, we compared the gene expression profiles in SK-N-SH cells and two subtypes of SH-SY5Y cells (SH-SY5Y-A and SH-SY5Y-E), each of which show a different phenotype during RA-mediated differentiation. SH-SY5Y-A cells differentiated in the presence of RA, whereas RA-treated SH-SY5Y-E cells required additional treatment with brain-derived neurotrophic factor (BDNF) for full differentiation. After exposing cells to a PI3K inhibitor, LY294002, we identified 386 genes and categorised these genes into two clusters dependent on the PI3K signalling pathway during RA-mediated differentiation in SH-SY5Y-A cells. Transcriptional regulation of the gene cluster, including 158 neural genes, was greatly reduced in SK-N-SH cells and partially impaired in SH-SY5Y-E cells, which is consistent with a defect in the neuronal phenotype of these cells. Additional stimulation with BDNF induced a set of neural genes that were down-regulated in RA-treated SH-SY5Y-E cells but were abundant in differentiated SH-SY5Y-A cells. We identified gene clusters controlled by PI3K- and TRKB-mediated signalling pathways during the differentiation of two subtypes of SH-SY5Y cells. The TRKB-mediated bypass pathway compensates for impaired neural function generated by defects in several signalling pathways, including PI3K in SH-SY5Y-E cells. Our expression profiling data will be useful for further elucidation of the signal transduction-transcriptional network involving PI3K or TRKB.

Mathematical Modeling of Hybrid Electrical Engineering Systems

Directory of Open Access Journals (Sweden)

A. A. Lobaty

2016-01-01

Full Text Available A large class of systems that have found application in various industries and households, electrified transportation facilities and energy sector has been classified as electrical engineering systems. Their characteristic feature is a combination of continuous and discontinuous modes of operation, which is reflected in the appearance of a relatively new term “hybrid systems”. A wide class of hybrid systems is pulsed DC converters operating in a pulse width modulation, which are non-linear systems with variable structure. Using various methods for linearization it is possible to obtain linear mathematical models that rather accurately simulate behavior of such systems. However, the presence in the mathematical models of exponential nonlinearities creates considerable difficulties in the implementation of digital hardware. The solution can be found while using an approximation of exponential functions by polynomials of the first order, that, however, violates the rigor accordance of the analytical model with characteristics of a real object. There are two practical approaches to synthesize algorithms for control of hybrid systems. The first approach is based on the representation of the whole system by a discrete model which is described by difference equations that makes it possible to synthesize discrete algorithms. The second approach is based on description of the system by differential equations. The equations describe synthesis of continuous algorithms and their further implementation in a digital computer included in the control loop system. The paper considers modeling of a hybrid electrical engineering system using differential equations. Neglecting the pulse duration, it has been proposed to describe behavior of vector components in phase coordinates of the hybrid system by stochastic differential equations containing generally non-linear differentiable random functions. A stochastic vector-matrix equation describing dynamics of the

Neuroprotective Effect of Arctigenin via Upregulation of P-CREB in Mouse Primary Neurons and Human SH-SY5Y Neuroblastoma Cells

Science.gov (United States)

Zhang, Nan; Wen, Qingping; Ren, Lu; Liang, Wenbo; Xia, Yang; Zhang, Xiaodan; Zhao, Dan; Sun, Dong; Hu, Yv; Hao, Haiguang; Yan, Yaping; Zhang, Guangxian; Yang, Jingxian; Kang, Tingguo

2013-01-01

Arctigenin (Arc) has been shown to act on scopolamine-induced memory deficit mice and to provide a neuroprotective effect on cultured cortical neurons from glutamate-induced neurodegeneration through mechanisms not completely defined. Here, we investigated the neuroprotective effect of Arc on H89-induced cell damage and its potential mechanisms in mouse cortical neurons and human SH-SY5Y neuroblastoma cells. We found that Arc prevented cell viability loss induced by H89 in human SH-SY5Y cells. Moreover, Arc reduced intracellular beta amyloid (Aβ) production induced by H89 in neurons and human SH-SY5Y cells, and Arc also inhibited the presenilin 1(PS1) protein level in neurons. In addition, neural apoptosis in both types of cells, inhibition of neurite outgrowth in human SH-SY5Y cells and reduction of synaptic marker synaptophysin (SYN) expression in neurons were also observed after H89 exposure. All these effects induced by H89 were markedly reversed by Arc treatment. Arc also significantly attenuated downregulation of the phosphorylation of CREB (p-CREB) induced by H89, which may contribute to the neuroprotective effects of Arc. These results demonstrated that Arc exerted the ability to protect neurons and SH-SY5Y cells against H89-induced cell injury via upregulation of p-CREB. PMID:24025424

Neuroprotective Effect of Arctigenin via Upregulation of P-CREB in Mouse Primary Neurons and Human SH-SY5Y Neuroblastoma Cells

Directory of Open Access Journals (Sweden)

Tingguo Kang

2013-09-01

Full Text Available Arctigenin (Arc has been shown to act on scopolamine-induced memory deficit mice and to provide a neuroprotective effect on cultured cortical neurons from glutamate-induced neurodegeneration through mechanisms not completely defined. Here, we investigated the neuroprotective effect of Arc on H89-induced cell damage and its potential mechanisms in mouse cortical neurons and human SH-SY5Y neuroblastoma cells. We found that Arc prevented cell viability loss induced by H89 in human SH-SY5Y cells. Moreover, Arc reduced intracellular beta amyloid (Aβ production induced by H89 in neurons and human SH-SY5Y cells, and Arc also inhibited the presenilin 1(PS1 protein level in neurons. In addition, neural apoptosis in both types of cells, inhibition of neurite outgrowth in human SH-SY5Y cells and reduction of synaptic marker synaptophysin (SYN expression in neurons were also observed after H89 exposure. All these effects induced by H89 were markedly reversed by Arc treatment. Arc also significantly attenuated downregulation of the phosphorylation of CREB (p-CREB induced by H89, which may contribute to the neuroprotective effects of Arc. These results demonstrated that Arc exerted the ability to protect neurons and SH-SY5Y cells against H89-induced cell injury via upregulation of p-CREB.

Electrical performances of pyroelectric bimetallic strip heat engines describing a Stirling cycle

Science.gov (United States)

Arnaud, A.; Boughaleb, J.; Monfray, S.; Boeuf, F.; Cugat, O.; Skotnicki, T.

2015-12-01

This paper deals with the analytical modeling of pyroelectric bimetallic strip heat engines. These devices are designed to exploit the snap-through of a thermo-mechanically bistable membrane to transform a part of the heat flowing through the membrane into mechanical energy and to convert it into electric energy by means of a piezoelectric layer deposited on the surface of the bistable membrane. In this paper, we describe the properties of these heat engines in the case when they complete a Stirling cycle, and we evaluate the performances (available energy, Carnot efficiency...) of these harvesters at the macro- and micro-scale.

GLOBE and the Earth SySTEM Model in Teacher Preparation

Science.gov (United States)

Jabot, M.; Moore, J.; Dorofy, P.

2017-12-01

This presentation will share the growing body of work linking ArcMap and GLOBE and the Earth SySTEM approach in the development of preservice teachers. Our work is linking the power of ArcMap with the vast database of GLOBE in a unique way that links the power of geospatial technologies in shaping the planning for and delivery of science instruction in the P-5 classroom.

Identification and classification of genes regulated by phosphatidylinositol 3-kinase- and TRKB-mediated signalling pathways during neuronal differentiation in two subtypes of the human neuroblastoma cell line SH-SY5Y

OpenAIRE

Nishida, Yuichiro; Adati, Naoki; Ozawa, Ritsuko; Maeda, Aasami; Sakaki, Yoshiyuki; Takeda, Tadayuki

2008-01-01

Abstract Background SH-SY5Y cells exhibit a neuronal phenotype when treated with all-trans retinoic acid (RA), but the molecular mechanism of activation in the signalling pathway mediated by phosphatidylinositol 3-kinase (PI3K) is unclear. To investigate this mechanism, we compared the gene expression profiles in SK-N-SH cells and two subtypes of SH-SY5Y cells (SH-SY5Y-A and SH-SY5Y-E), each of which show a different phenotype during RA-mediated differentiation. Findings SH-SY5Y-A cells diffe...

Design basis and requirements for 241-SY modular exhauster mechanical installation

International Nuclear Information System (INIS)

Kriskovich, J.R.

1994-01-01

A new ventilation system is being installed to serve as the K-1 primary exhauster. The existing K-1 primary exhauster will then become the backup. This ventilation system services waste tanks 241-SY-101, 102 and 103. The nominal flow rate through the ventilation system is 1,000 cfm. The new ventilation system will contain a moisture eliminator, a heater, a prefilter, two stages of HEPA filtration, an exhaust fan, a stack and stack sampling system. The purpose of this document is to serve as the design and functional requirements for the mechanical installation of the new 241-SY modular exhauster. The mechanical installation will include modifying the existing ductwork (i.e., installing a ''T'' to connect the new exhauster to the existing system), modifying the existing condensate drain lines to accommodate the new lines associated with the new exhauster, a maintenance platform near the stack of the new exhauster, guy wires and guy wire footings to support the stack of the new exhauster, as well as other miscellaneous tasks associated with the mechanical installation design effort

Regulation of nicotinic receptor subtypes following chronic nicotinic agonist exposure in M10 and SH-SY5Y neuroblastoma cells

DEFF Research Database (Denmark)

Warpman, U; Friberg, L; Gillespie, A

1998-01-01

investigated in human neuroblastoma SH-SY5Y cells (expressing alpha3, alpha5, beta2, and beta4 nAChR subunits). Nicotine exhibited a 14 times lower affinity for the nAChRs in SH-SY5Y cells as compared with M10 cells, whereas epibatidine showed similar affinities for the nAChRs expressed in the two cell lines...

Project of the Year Submittal SY-101 Surface Level Rise Remediation Project

International Nuclear Information System (INIS)

BAUER, R.E.

2001-01-01

CH2M HILL Hanford Group is pleased to nominate the SY-101 Surface Level Rise Remediation Project (SLRRP) for the Project Management Institute's consideration as International Project of the Year for 2001. We selected this project as being our best recent example of effective project management, having achieved and exceeded our client's expectations in resolving urgent safety issues related to the storage of high level nuclear waste. In reflection, we consider the SY-101 SLRRP to be a prime example of safe and effective project delivery. The pages that follow present the tools and techniques employed to manage this complex and technically challenging project. Our objective in submitting this nomination is twofold--to share the lessons we have learned with other organizations, and to honor the men and women who contributed to this endeavor. It was by their diligent effort that the successes we relate here were accomplished 10 months ahead of schedule and one million dollars below the authorized budget

Virtual reality as a new trend in mechanical and electrical engineering education

Directory of Open Access Journals (Sweden)

Kamińska Dorota

2017-12-01

Full Text Available In their daily practice, academics frequently face lack of access to modern equipment and devices, which are currently in use on the market. Moreover, many students have problems with understanding issues connected to mechanical and electrical engineering due to the complexity, necessity of abstract thinking and the fact that those concepts are not fully tangible. Many studies indicate that virtual reality can be successfully used as a training tool in various domains, such as development, health-care, the military or school education. In this paper, an interactive training strategy for mechanical and electrical engineering education shall be proposed. The prototype of the software consists of a simple interface, meaning it is easy for comprehension and use. Additionally, the main part of the prototype allows the user to virtually manipulate a 3D object that should be analyzed and studied. Initial studies indicate that the use of virtual reality can contribute to improving the quality and efficiency of higher education, as well as qualifications, competencies and the skills of graduates, and increase their competitiveness in the labour market.

Virtual reality as a new trend in mechanical and electrical engineering education

Science.gov (United States)

Kamińska, Dorota; Sapiński, Tomasz; Aitken, Nicola; Rocca, Andreas Della; Barańska, Maja; Wietsma, Remco

2017-12-01

In their daily practice, academics frequently face lack of access to modern equipment and devices, which are currently in use on the market. Moreover, many students have problems with understanding issues connected to mechanical and electrical engineering due to the complexity, necessity of abstract thinking and the fact that those concepts are not fully tangible. Many studies indicate that virtual reality can be successfully used as a training tool in various domains, such as development, health-care, the military or school education. In this paper, an interactive training strategy for mechanical and electrical engineering education shall be proposed. The prototype of the software consists of a simple interface, meaning it is easy for comprehension and use. Additionally, the main part of the prototype allows the user to virtually manipulate a 3D object that should be analyzed and studied. Initial studies indicate that the use of virtual reality can contribute to improving the quality and efficiency of higher education, as well as qualifications, competencies and the skills of graduates, and increase their competitiveness in the labour market.

Study of hydrogen engine for a hybrid electric vehicle. 1; Hybrid denki jidoshayo suiso engine ni kansuru kenkyu. 1

Energy Technology Data Exchange (ETDEWEB)

Iguchi, T.; Numata, T. Hiruma, M.; Yamane, K.; Nakajima, Y.; Furuhama, S. [Musashi Institute of Technology, Tokyo (Japan); Takagi, Y. [Nissan Motor Co. Ltd., Tokyo (Japan)

1998-10-15

Study was made on application of a hydrogen engine to series hybrid electric vehicle (SHEV). Power of 20kW (for steady driving of a vehicle of 1t in total weight on flat road surface at 100km/h), and NOx emission concentration equivalent to that of EZEV (equivalent zero emission vehicle) were used as target performance. One of the merits of using a hydrogen engine for HEV is that conventional high-reliability gasoline engines can be used as hydrogen engines only by a bit of modification. A modified conventional 4-cylinder 4-cycle gasoline engine was used for this study. Hydrogen gas was continuously supplied through an intake manifold for premixed combustion by spark ignition. Brake thermal efficiency was improved from 30.5% to 35.5% by use of a high compression ratio and reduction of friction loss. NOx emission concentration could be controlled within 10ppm by ultra-lean combustion even at excess air ratios over 2.5. Both high efficiency and low emission were achieved at the same time around 3000rpm in engine revolution. 4 refs., 12 figs., 1 tab.

Java Based Symbolic Circuit Solver For Electrical Engineering Curriculum

Directory of Open Access Journals (Sweden)

Ruba Akram Amarin

2012-11-01

Full Text Available The interactive technical electronic book, TechEBook, currently under development at the University of Central Florida (UCF, introduces a paradigm shift by replacing the traditional electrical engineering course with topic-driven modules that provide a useful tool for engineers and scientists. The TechEBook comprises the two worlds of classical circuit books and interactive operating platforms such as iPads, laptops and desktops. The TechEBook provides an interactive applets screen that holds many modules, each of which has a specific application in the self learning process. This paper describes one of the interactive techniques in the TechEBook known as Symbolic Circuit Solver (SymCirc. The SymCirc develops a versatile symbolic based linear circuit with a switches solver. The solver works by accepting a Netlist and the element that the user wants to find the voltage across or current on, as input parameters. Then it either produces the plot or the time domain expression of the output. Frequency domain plots or Symbolic Transfer Functions are also produced. The solver gets its input from a Web-based GUI circuit drawer developed at UCF. Typical simulation tools that electrical engineers encounter are numerical in nature, that is, when presented with an input circuit they iteratively solve the circuit across a set of small time steps. The result is represented as a data set of output versus time, which can be plotted for further inspection. Such results do not help users understand the ultimate nature of circuits as Linear Time Invariant systems with a finite dimensional basis in the solution space. SymCirc provides all simulation results as time domain expressions composed of the basic functions that exclusively include exponentials, sines, cosines and/or t raised to any power. This paper explains the motivation behind SymCirc, the Graphical User Interface front end and how the solver actually works. The paper also presents some examples and

Atractylenolide-I Protects Human SH-SY5Y Cells from 1-Methyl-4-Phenylpyridinium-Induced Apoptotic Cell Death

Directory of Open Access Journals (Sweden)

Sandeep Vasant More

2017-05-01

Full Text Available Oxidative stress and apoptosis are the major mechanisms that induce dopaminergic cell death. Our study investigates the protective effects of atractylenolide-I (ATR-I on 1-methyl-4-phenylpyridinium (MPP+-induced cytotoxicity in human dopaminergic SH-SY5Y cells, as well as its underlying mechanism. Our experimental data indicates that ATR-I significantly inhibits the loss of cell viability induced by MPP+ in SH-SY5Y cells. To further unravel the mechanism, we examined the effect of ATR-I on MPP+-induced apoptotic cell death characterized by an increase in the Bax/Bcl-2 mRNA ratio, the release of cytochrome-c, and the activation of caspase-3 leading to elevated levels of cleaved poly(ADP-ribose polymerase (PARP resulting in SH-SY5Y cell death. Our results demonstrated that ATR-I decreases the level of pro-apoptotic proteins induced by MPP+ and also restored Bax/Bcl-2 mRNA levels, which are critical for inducing apoptosis. In addition, ATR-I demonstrated a significant increase in the protein expression of heme-oxygenase in MPP+-treated SH-SY5Y cells. These results suggest that the pharmacological effect of ATR-I may be, at least in part, caused by the reduction in pro-apoptotic signals and also by induction of anti-oxidant protein.

101-SY Dome pressure issues surrounding mitigation pump decontamination during removal

International Nuclear Information System (INIS)

Shaw, S.W.

1995-01-01

This document addresses issues related to use of the spraywands and ring used to decontaminate the mitigation pump installed in 101-SY. It has been determined that use of the wands will influence tank dome pressures as a function of ventilation system configuration, spray drop size, rinse water temperature, and rate at which spraywand flows are established

Identification and classification of genes regulated by phosphatidylinositol 3-kinase- and TRKB-mediated signalling pathways during neuronal differentiation in two subtypes of the human neuroblastoma cell line SH-SY5Y

Directory of Open Access Journals (Sweden)

Sakaki Yoshiyuki

2008-10-01

Full Text Available Abstract Background SH-SY5Y cells exhibit a neuronal phenotype when treated with all-trans retinoic acid (RA, but the molecular mechanism of activation in the signalling pathway mediated by phosphatidylinositol 3-kinase (PI3K is unclear. To investigate this mechanism, we compared the gene expression profiles in SK-N-SH cells and two subtypes of SH-SY5Y cells (SH-SY5Y-A and SH-SY5Y-E, each of which show a different phenotype during RA-mediated differentiation. Findings SH-SY5Y-A cells differentiated in the presence of RA, whereas RA-treated SH-SY5Y-E cells required additional treatment with brain-derived neurotrophic factor (BDNF for full differentiation. After exposing cells to a PI3K inhibitor, LY294002, we identified 386 genes and categorised these genes into two clusters dependent on the PI3K signalling pathway during RA-mediated differentiation in SH-SY5Y-A cells. Transcriptional regulation of the gene cluster, including 158 neural genes, was greatly reduced in SK-N-SH cells and partially impaired in SH-SY5Y-E cells, which is consistent with a defect in the neuronal phenotype of these cells. Additional stimulation with BDNF induced a set of neural genes that were down-regulated in RA-treated SH-SY5Y-E cells but were abundant in differentiated SH-SY5Y-A cells. Conclusion We identified gene clusters controlled by PI3K- and TRKB-mediated signalling pathways during the differentiation of two subtypes of SH-SY5Y cells. The TRKB-mediated bypass pathway compensates for impaired neural function generated by defects in several signalling pathways, including PI3K in SH-SY5Y-E cells. Our expression profiling data will be useful for further elucidation of the signal transduction-transcriptional network involving PI3K or TRKB.

Integrated electric circuit engineering system in LSI design center, Konami Kogyo Co. Ltd

Energy Technology Data Exchange (ETDEWEB)

Kamitsuki, Kagehiko; Tanaka, Tomiaki

1988-08-26

Development of the integrated engineering system is presented which designs and manufactures the hardwares, softwares and cases of electronic game products with LSI integratedly as an experiment. The system is intended to reduce the number of each development of the parts, to verify each other by comparing each parts with the product concept during the development, to reduce modifications, and to shorten development periods. The main subsystems are an electric circuit CAD for LSI designs and a mechanical CAD for case or printed circuit board designs. The LSI development period has been shortened up to one month by a larger capacity computer and higher speed simulator, and the electric circuit engineering system capable of keeping step with the software development has been approximately completed. In the future, the system will be intended to introduce an expert system or a visual system capable of predicting the final product during a logical design period. (10 figs, 1 photo)

Benefit using reasonable regulations in USA, how to skill up on professional engineers, apply international code, standard, and regulation

International Nuclear Information System (INIS)

Turner, S.L.; Morokuzu, Muneo; Amano, Osamu

2005-01-01

The reasonable regulations in USA consist of a graduated approach and a risk informed approach (RIA). RIA rationalizes the regulations on the basis of data of operations etc. PSA (Probabilistic Safety Assessment), a general method of RIA, is explained in detail. The benefits of nuclear power plant using RIA are increase of the rate of operation, visualization of risk, application of design standard and design, cost down of nuclear fuel cycle, waste, production and operation, and safety. RIA is supported by the field data, code, standard, regulation and professional engineers. The effects of introduction of RIA are explained. In order to introduce RIA in Japan, all the parties concerned such as the regulation authorities, the electric power industries, makers, universities, have to understand it and work together. A part of scientific society is stated. (S.Y.)

Acquisition and reduction of data obtained from tank 101-SY in-situ ball rheometer

International Nuclear Information System (INIS)

Shepard, C.L.; Chieda, M.A.; Kirihara, L.J.; Phillips, J.R.; Shekarriz, A.; Terrones, G.; Abbott, J.; Unal, C.; Pasamehmetoglu, K.O.; Graham, A.

1995-02-01

Development of the ball rheometer to measure rheological properties and density of the waste in Hanford Tank 241-SY-101 will be completed around September 1994. This instrument is expected to provide the first-of-its-kind in-situ measurements of the fluid properties of the waste contained within this tank. A mixer pump has been installed in this tank, and this pump has been very successful at mitigating the flammable gas problem associated with Tank 101-SY. The ball rheometer will serve as a diagnostic tool for judging the effectiveness of mixing in Tank 101-SY and others and will be one of few in-situ probes available for diagnostic measurements. Based on experiments performed at Los Alamos National Laboratory and Pacific Northwest Laboratory, it is believed that a generalized Bingham fluid model (Herschel-Bulkley fluid model) may be useful for describing at least some of the waste contained in Tank 101-SY, and data obtained in the tank will initially be reduced using this fluid model. The single largest uncertainty in the determination of the drag force on the ball is the drag force which will be experienced by the cable attached to the ball. This drag can be a substantial fraction of the total drag when the ball is deep within the tank. It is expected that the fluid properties may be history dependent, thus rheological properties of the undisturbed fluid may be different from the same properties after the fluid has been disturbed by passage of the ball. The data collection strategy allows the determination of the waste fluid rheology both in the undisturbed state and after it has been disturbed by the ball. Unlike the rheological parameters, measurement of density requires no model for its interpretation; however, the effects of yield stress may need to be accounted for. This measurement can be made with fairly good accuracy and may provide the most useful data in determination of mixer pump effectiveness

Work plan for transition of SY-101 hydrogen mitigation test project data acquisition and control system (DACS-1)

International Nuclear Information System (INIS)

McClees, J.; Truitt, R.W.

1994-01-01

The purpose of this effort is to transfer operating and maintenance responsibility for the 241-SY-101 data acquisition and control system (DACS-1) from Los Alamos National Laboratory to Westinghouse Hanford Company. This work plan defines the tasks required for a successful turnover. It identifies DACS-1 transition, deliverables, responsible organizations and individuals, interfaces, cost, and schedule. The transition plan will discuss all required hardware, software, documentation, maintenance, operations, and training for use at Hanford Waste Tank 241-SY-101. The transfer of responsibilities for DACS-1 to WHC is contingent on final approval of applicable Acceptance for Beneficial Use documentation by Waste Tank Operations. The DACS-1 was designed to provide data monitoring, display, and storage for Tank 241-SY-101. The DACS-1 also provides alarm and control of all the hydrogen mitigation testing systems, as well as ancillary systems and equipment (HVAC, UPS, etc.) required to achieve safe and reliable operation of the testing systems in the tank

Engine-integrated solid oxide fuel cells for efficient electrical power generation on aircraft

Science.gov (United States)

Waters, Daniel F.; Cadou, Christopher P.

2015-06-01

This work investigates the use of engine-integrated catalytic partial oxidation (CPOx) reactors and solid oxide fuel cells (SOFCs) to reduce fuel burn in vehicles with large electrical loads like sensor-laden unmanned air vehicles. Thermodynamic models of SOFCs, CPOx reactors, and three gas turbine (GT) engine types (turbojet, combined exhaust turbofan, separate exhaust turbofan) are developed and checked against relevant data and source material. Fuel efficiency is increased by 4% and 8% in the 50 kW and 90 kW separate exhaust turbofan systems respectively at only modest cost in specific power (8% and 13% reductions respectively). Similar results are achieved in other engine types. An additional benefit of hybridization is the ability to provide more electric power (factors of 3 or more in some cases) than generator-based systems before encountering turbine inlet temperature limits. A sensitivity analysis shows that the most important parameters affecting the system's performance are operating voltage, percent fuel oxidation, and SOFC assembly air flows. Taken together, this study shows that it is possible to create a GT-SOFC hybrid where the GT mitigates balance of plant losses and the SOFC raises overall system efficiency. The result is a synergistic system with better overall performance than stand-alone components.

Identifying and Investigating Difficult Concepts in Engineering Mechanics and Electric Circuits. Research Brief

Science.gov (United States)

Streveler, Ruth; Geist, Monica; Ammerman, Ravel; Sulzbach, Candace; Miller, Ronald; Olds, Barbara; Nelson, Mary

2007-01-01

This study extends ongoing work to identify difficult concepts in thermal and transport science and measure students' understanding of those concepts via a concept inventory. Two research questions provided the focal point: "What important concepts in electric circuits and engineering mechanics do students find difficult to learn?" and…

Simulation of a hot air engine for a generation of electricity using biogas for Tanzania rural application

International Nuclear Information System (INIS)

Mkiramweni, L.L.N.; Msaki, P.; Mshoro, I.B.

2007-01-01

At the moment, about 80% of the rural population in Tanzania lacks grid electricity. As a result, up to 90% of energy requirements in rural areas are met by firewood and hence causing deforestation. In the present paper, the authors are advocating the application of biogas to generate electricity in rural areas to minimise deforestation. Preliminary study conducted has shown that the power required in rural areas is about 10kW for household and small economic activities. As such, the authors have investigated the possibility of applying a hot air engine using biogas as a source of energy to generate electricity. The study involved simulation of hot air engine using a Stirling Numerical Analysis Program (SNAP) with use modifiable code. In the exercise, the performance of the simulated engine was assessed with helium, hydrogen and air as working media. Reheat loss and pressure losses were also assessed for varies range of engine power and efficiency. It has been observed that with helium and hydrogen as working gas, the power output could easily reach 10kW, which is sufficient for rural household application. However, with air the engine could realise only 4kW under similar conditions. It has further been observed that air has bigger and more viscous molecular with lower thermal conductivity and heat capacity, which results in higher losses. This implies that a relatively bigger engine need be employed for running with air. However, high initial cost will be offset by the reduction in operating cost, since air is freely available. For proper operation of the engine heater temperature should be maintained above 630(deg)C, which is realizable with biogas having a flame temperature of about 870(deg)C. (author)

Electric Engines to Gas

International Nuclear Information System (INIS)

Novoa, M.G.

1996-01-01

Environmental pollution and specially air pollution, it is produced in a wide range by exhaust gases of internal combustion engines, those which are used to generate energy. Direct use of fossil combustibles as petroleum derivatives and coal produces large quantities of harmful elements to ecology equilibrium. Whit the objective of reducing this pollutant load has been development thermoelectric plants whit turbine to gas or to steam, those which are moved by internal combustion engines. Gas engines can burn most of available gases, as both solid waste and wastewater treatment plants biogas, propane gas, oil-liquefied gas or natural gas. These gases are an alternative and clean energy source, and its efficiency in internal combustion engines is highest compared whit other combustibles as gasoline-motor or diesel

Electric circuit theory applied electricity and electronics

CERN Document Server

Yorke, R

1981-01-01

Electric Circuit Theory provides a concise coverage of the framework of electrical engineering. Comprised of six chapters, this book emphasizes the physical process of electrical engineering rather than abstract mathematics. Chapter 1 deals with files, circuits, and parameters, while Chapter 2 covers the natural and forced response of simple circuit. Chapter 3 talks about the sinusoidal steady state, and Chapter 4 discusses the circuit analysis. The fifth chapter tackles frequency response of networks, and the last chapter covers polyphase systems. This book will be of great help to electrical

A comparison of hydrogen-fueled fuel cells and combustion engines for electric utility applications

International Nuclear Information System (INIS)

Schoenung, S.M.

2000-01-01

Hydrogen-fueled systems have been proposed for a number of stationary electric generation applications including remote power generation, load management, distribution system peak shaving, and reliability or power quality enhancement. Hydrogen fueling permits clean, low pollution operation. This is particularly true for systems that use hydrogen produced from electrolysis, rather than the reforming of hydrocarbon fuels. Both fuel cells and combustion engines are suitable technologies for using hydrogen in many electric utility applications. This paper presents results from several studies performed for the U.S. Department of Energy Hydrogen Program. A comparison between the two technologies shows that, whereas fuel cells are somewhat more energy efficient, combustion engine technology is less expensive. In this paper, a comparison of the two technologies is presented, with an emphasis on distributed power and power quality applications. The special case of a combined distributed generation I hydrogen refueling station is also addressed. The comparison is made on the basis of system costs and benefits, but also includes a comparison of technology status: power ratings and response time. A discussion of pollutant emissions and pollutant control strategies is included. The results show those electric utility applications for which each technology is best suited. (author)

Generation of net electric power with a tokamak reactor under foreseeable physical and engineering conditions

International Nuclear Information System (INIS)

Hiwatari, R.; Asaoka, Y.; Okano, K.; Yoshida, T.; Tomabechi, K.

2004-01-01

This study reveals for the first time the plasma performance required for a tokamak reactor to generate net electric power under foreseeable engineering conditions. It was found that the reference plasma performance of the ITER inductive operation mode with β N = 1.8, HH = 1.0, andf nGW 0.85 had sufficient potential to achieve the electric break-even condition (net electric power P e net = 0MW) under the following engineering conditions: machine major radius 6.5m ≤ R p ≤ 8.5m, the maximum magnetic field on TF coils B tmax = 16 T, thermal efficiency η e 30%, and NBI system efficiency η NBI = 50%. The key parameters used in demonstrating net electric power generation in tokamak reactors are β N and fη GW . ≥ 3.0 is required for P e net ∼ 600MW with fusion power P f ∼ 3000MW. On the other hand, fη GW ≥ 1.0 is inevitable to demonstrate net electric power generation, if high temperatures, such as average temperatures of T ave > 16 keV, cannot be selected for the reactor design. To apply these results to the design of a tokamak reactor for demonstrating net electric power generation, the plasma performance diagrams on the Q vs P f (energy multiplication factor vs fusion power) space for several major radii (i.e. 6.5, 7.5, and 8.5 m) were depicted. From these figures, we see that a design with a major radius R p ∼ 7.5m seems preferable for demonstrating net electric power generation when one aims at early realization of fusion energy. (author)

Caspase Activation of p21-Activated Kinase 2 Occurs During Cisplatin-Induced Apoptosis of SH-SY5Y Neuroblastoma Cells and in SH-SY5Y Cell Culture Models of Alzheimer’s and Parkinson’s Disease

Directory of Open Access Journals (Sweden)

Jerry W. Marlin

2010-04-01

Full Text Available p21-activated kinase 2 (PAK-2 appears to have a dual function in the regulation of cell survival and cell death. Activation of full-length PAK-2 by the p21 G-proteins Rac or Cdc42 stimulates cell survival. However, PAK-2 is unique among the PAK family because it is also activated through proteolytic cleavage by caspase 3 or similar caspases to generate the constitutively active PAK-2p34 fragment. Caspase activation of PAK-2 correlates with the induction of apoptosis in response to many stimuli and recombinant expression of PAK-2p34 has been shown to stimulate apoptosis in several human cell lines. Here, we show that caspase activation of PAK-2 also occurs during cisplatin-induced apoptosis of SH-SY5Y neuroblastoma cells as well as in SH-SY5Y cell culture models for Alzheimer’s and Parkinson’s disease. Inhibition of mitochondrial complex I or of ubiquitin/proteasome-mediated protein degradation, which both appear to be involved in Parkinson’s disease, induce apoptosis and caspase activation of PAK-2 in SH-SY5Y cells. Overexpression of the amyloid precursor protein, which results in accumulation and aggregation of β-amyloid peptide, the main component of β-amyloid plaques in Alzheimer’s disease, also induces apoptosis and caspase activation of PAK-2 in SH-SY5Y cells. Expression of the PAK-2 regulatory domain inhibits caspase-activated PAK-2p34 and prevents apoptosis in 293T human embryonic kidney cells, indicating that caspase activation of PAK-2 is directly involved in the apoptotic response. This is the first evidence that caspase activation of PAK-2 correlates with apoptosis in cell culture models of Alzheimer’s and Parkinson’s disease and that selective inhibition of caspase-activated PAK-2p34 could prevent apoptosis.

5th International Conference on Electrical Engineering and Automatic Control

CERN Document Server

Yao, Yufeng

2016-01-01

On the basis of instrument electrical and automatic control system, the 5th International Conference on Electrical Engineering and Automatic Control (CEEAC) was established at the crossroads of information technology and control technology, and seeks to effectively apply information technology to a sweeping trend that views control as the core of intelligent manufacturing and life. This book takes a look forward into advanced manufacturing development, an area shaped by intelligent manufacturing. It highlights the application and promotion of process control represented by traditional industries, such as the steel industry and petrochemical industry; the technical equipment and system cooperative control represented by robot technology and multi-axis CNC; and the control and support of emerging process technologies represented by laser melting and stacking, as well as the emerging industry represented by sustainable and intelligent life. The book places particular emphasis on the micro-segments field, such as...

A discussion on the safety classification of the tank 241-SY-101 mixer pump

International Nuclear Information System (INIS)

Van Vleet, R.J.

1997-01-01

An analysis, consistent with the methodology used in the draft TWRS FSAR (HNF-SD-WM-SAR-067), is presented to show that the classification of the mixer pump in tank 241-SY-101 should be safety significant

The effect of dilution on the gas-retention behavior of Tank 241-SY-101 waste

International Nuclear Information System (INIS)

Bredt, P.R.; Tingey, S.M.; Shade, E.H.

1995-09-01

The effect of dilution on gas retention in waste from Tank 241-SY-101 was investigated. A composite sample was prepared from material collected during the Window ''C'' and Window ''E'' sampling events. The composite contained material from both the convective and nonconvective layer in the proportions existing in the tank. Operation of the mixer pump in Tank 241-SY-101 has homogenized the tank material, and dilution of the current waste would require additional mixing; therefore, no attempt was made to use unhomogenized tank waste to prepare the composite. The composite was diluted with 2 M NaOH at ratios of 0.5:1, 0.75: 1, 1:1, and 3:1 per volume (2 M NaOH:tank waste)

Acetaldehyde Induces Cytotoxicity of SH-SY5Y Cells via Inhibition of Akt Activation and Induction of Oxidative Stress

Directory of Open Access Journals (Sweden)

Tingting Yan

2016-01-01

Full Text Available Excessive alcohol consumption can lead to brain tissue damage and cognitive dysfunction. It has been shown that heavy drinking is associated with an earlier onset of neurodegenerative diseases such as Alzheimer’s disease. Acetaldehyde, the most toxic metabolite of ethanol, is speculated to mediate the brain tissue damage and cognitive dysfunction induced by the chronic excessive consumption of alcohol. However, the exact mechanisms by which acetaldehyde induces neurotoxicity are not totally understood. In this study, we investigated the cytotoxic effects of acetaldehyde in SH-SY5Y cells and found that acetaldehyde induced apoptosis of SH-SY5Y cells by downregulating the expression of antiapoptotic Bcl-2 and Bcl-xL and upregulating the expression of proapoptotic Bax. Acetaldehyde treatment led to a significant decrease in the levels of activated Akt and cyclic AMP-responsive element binding protein (CREB. In addition, acetaldehyde induced the activation of p38 mitogen-activated protein kinase (MAPK while inhibiting the activation of extracellular signal-regulated kinases (ERKs, p44/p42MAPK. Meanwhile, acetaldehyde treatment caused an increase in the production of reactive oxygen species and elevated the oxidative stress in SH-SY5Y cells. Therefore, acetaldehyde induces cytotoxicity of SH-SY5Y cells via promotion of apoptotic signaling, inhibition of cell survival pathway, and induction of oxidative stress.

Design basis and requirements for 241-SY Modular Exhauster concrete pad and retaining wall

International Nuclear Information System (INIS)

Kriskovich, J.R.

1994-01-01

The purpose of this document is to serve as the design and functional requirements for a concrete pad for the new 241-SY Modular Exhauster and for a retaining wall to be built near the new ventilation systems

Engineering electric and magnetic dipole coupling in arrays of dielectric nanoparticles

Science.gov (United States)

Li, Jiaqi; Verellen, Niels; Van Dorpe, Pol

2018-02-01

Dielectric nanoparticles with both strong electric and magnetic dipole (ED and MD) resonances offer unique opportunities for efficient manipulation of light-matter interactions. Here, based on numerical simulations, we show far-field diffractive coupling of the ED and MD modes in a periodic rectangular array. By using unequal periodicities in the orthogonal directions, each dipole mode is separately coupled and strongly tuned. With this method, the electric and magnetic response of the dielectric nanoparticles can be deliberately engineered to accomplish various optical functionalities. Remarkably, an ultra-sharp MD resonance with sub-10 nm linewidth is achieved with a large enhancement factor for the magnetic field intensity on the order of ˜103. Our results will find useful applications for the detection of chemical and biological molecules as well as the design of novel photonic metadevices.

A Study of Second-Year Engineering Students' Alternative Conceptions about Electric Potential, Current Intensity and Ohm's Law

Science.gov (United States)

Periago, M. Cristina; Bohigas, Xavier

2005-01-01

The aim of this research was to evaluate and analyse second-year industrial engineering and chemical engineering students prior knowledge of conceptual aspects of "circuit theory". Specifically, we focused on the basic concepts of electric potential and current intensity and on the fundamental relationship between them as expressed by Ohm's law.…

SyZyGy: A straight interferometric spacecraft system for gravity wave observations

International Nuclear Information System (INIS)

Estabrook, F.B.; Armstrong, J.W.; Tinto, Massimo; Folkner, William

2003-01-01

We consider a spaceborne gravitational wave (GW) detector formed by three spacecraft in a linear array, coherently exchanging laser beams and using the data combinations of time-delay interferometry (TDI). We previously showed how the measured time series of Doppler shifts in the six one-way laser links between spacecraft pairs in a general unequal-arm triangular configuration can be combined, using TDI, to exactly cancel the otherwise overwhelming phase noise of the lasers while retaining sensitivity to GWs. Here we apply TDI, unfolding the general triangular configuration, to the special case of a linear array of three spacecraft. We show that such an array ('SyZyGy') has, compared with an equilateral triangle GW detector of the same scale, a degraded (but non-zero) sensitivity at low frequencies [f -4 -10 -1 Hz). SyZyGy with ∼1 light-second scale could, for the same instrumental assumptions as LISA, make observations in this intermediate frequency GW band with 5σ sensitivity to sinusoidal waves ≅2.5x10 -23 in a year's integration

Electric field engineering using quantum-size-effect-tuned heterojunctions

KAUST Repository

Adinolfi, V.

2013-07-03

A quantum junction solar cell architecture was recently reported that employs colloidal quantum dots (CQDs) on each side of the p-n junction. This architecture extends the range of design opportunities for CQD photovoltaics, since the bandgap can be tuned across the light-absorbing semiconductor layer via control over CQD size, employing solution-processed, room-temperature fabricated materials. We exploit this feature by designing and demonstrating a field-enhanced heterojunction architecture. We optimize the electric field profile within the solar cell through bandgap engineering, thereby improving carrier collection and achieving an increased open circuit voltage, resulting in a 12% improvement in power conversion efficiency.

The Competence Readiness of the Electrical Engineering Vocational High School Teachers in Manado towards the ASEAN Economic Community Blueprint in 2025

Directory of Open Access Journals (Sweden)

Fid Jantje Tasiam

2017-08-01

Full Text Available This paper presents the competence readiness of the electrical engineering vocational high school teachers in Manado towards ASEAN Economic Community blueprint in 2025. The objective of this study is to get the competencies readiness description of the electrical engineering vocational high school teachers in Manado towards ASEAN Economic Community blueprint in 2025. Method used quantitative and qualitative approach which the statistical analysis in quantitative and the inductive analysis used in qualitative. There were 46 teachers of the electrical engineering vocational high school in Manado observed. The results have shown that the competencies readiness of the electrical engineering vocational high school teachers in Manado such as: pedagogical, professional, personality, and social were 13.04%, 19.56%, 19.56%, and 19.56% respectively. The results were still far from the focus of the ASEAN economic community blueprint in 2025, so they need to be improved through in-house training, internship programs, school partnerships, distance learning, tiered training and special training, short courses in educational institutions, internal coaching by schools, discussion of educational issues, workshops, research and community service, textbook writing, learning media making, and the creation of technology and art.

Business | College of Engineering & Applied Science

Science.gov (United States)

& Environmental Engineering TA Online Application Civil & Environmental Engineering Research in Computer Science - FAQ's Computer Science TA Online Application Ph.D. Program in Computer Science Electrical Engineering Electrical Engineering TA Online Application Electrical Engineering Research

Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism.

Science.gov (United States)

Song, Ju-Xian; Choi, Mandy Yuen-Man; Wong, Kavin Chun-Kit; Chung, Winkie Wing-Yan; Sze, Stephen Cho-Wing; Ng, Tzi-Bun; Zhang, Kalin Yan-Bo

2012-01-21

Two active compounds, baicalein and its glycoside baicalin were found in the dried root of Scutellaria baicalensis Georgi, and reported to be neuroprotective in vitro and in vivo. This study aims to evaluate the protective effects of baicalein on the rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to parkinsonism. Cell viability and cytotoxicity were determined by MTT assay. The degree of nuclear apoptosis was evaluated with a fluorescent DNA-binding probe Hoechst 33258. The production of reactive oxidative species (ROS) and loss of mitochondrial membrane potential (ΔΨm) were determined by fluorescent staining with DCFH-DA and Rhodanmine 123, respectively. The expression of Bax, Bcl-2, cleaved caspase-3 and phosphorylated ERK1/2 was determined by the Western blots. Baicalein significantly increased viability and decreased rotenone-induced death of SH-SY5Y cells in a dose-dependent manner. Pre- and subsequent co-treatment with baicalein preserved the cell morphology and attenuated the nuclear apoptotic characteristics triggered by rotenone. Baicalein antagonized rotenone-induced overproduction of ROS, loss of ΔΨm, the increased expression of Bax, cleaved caspase-3 and phosphorylated ERK1/2 and the decreased expression of Bcl-2. The antioxidative effect, mitochondrial protection and modulation of anti-and pro-apoptotic proteins are related to the neuroprotective effects of baicalein against rotenone induced cell death in SH-SY5Y cells.

CompTIA security+ review guide exam SY0-401

CERN Document Server

Stewart , James M

2014-01-01

Focused review for the CompTIA Security+ certification exam The CompTIA Security+ certification offers tremendous opportunities for IT professionals. For those who want to take their careers to the next level, CompTIA Security+ Review Guide: Exam SY0-401 is here to serve as a great resource for certification preparation. This concise, focused guide is easy to use and is organized by each exam objective for quick review and reinforcement of key topics. You'll find information on network security, compliance and operational security, and threats and vulnerabilities. Additionally, this indispensa

Wind pumps for agriculture: Cost and environmental benefits (comparisons with electric and combustion engine driven pumps)

International Nuclear Information System (INIS)

Piccoli, F.

1991-01-01

After describing initial and running costs of a group of wind-pumps, the author calculates and compares, as far as agricultural and zootechnical purposes are concerned, the costs for each cubic meter of water extracted through wind-powered, electric and internal-combustion engines. The comparisons clearly show, under adequate wind conditions, that wind-pumps are economically more suitable than electric and motor pumps with similar delivery heads

Liberalization of electricity markets and energy security

International Nuclear Information System (INIS)

Yajima, Masayuki

2004-01-01

Liberalization of electricity markets begun in England in 1990 and became the trends of the times. Its effects on the energy security and atomic power generation are discussed. On the effects on energy security, change of construction of fuel of power generation, decrease of fuel feed by high efficiency of power generation, decrease of fuel stock by pressure of cost-cutting, increase of import rate of electricity, increase of power consumption with decrease of power cost, flexibility of supply contract, diversification of service, international cooperation on energy security and mutual dependence relation by international investment are discussed. On the effects of liberalization on the electricity markets, characteristics of nuclear power generation, risk of investment, effects of introduction of competition on development of the existing and new nuclear power generation, relation between development of nuclear power generation and market failure and what the government should do for development of nuclear power generation are discussed. (S.Y.)

Pre-exposure to 50 Hz magnetic fields modifies menadione-induced genotoxic effects in human SH-SY5Y neuroblastoma cells.

Directory of Open Access Journals (Sweden)

Jukka Luukkonen

Full Text Available BACKGROUND: Extremely low frequency (ELF magnetic fields (MF are generated by power lines and various electric appliances. They have been classified as possibly carcinogenic by the International Agency for Research on Cancer, but a mechanistic explanation for carcinogenic effects is lacking. A previous study in our laboratory showed that pre-exposure to ELF MF altered cancer-relevant cellular responses (cell cycle arrest, apoptosis to menadione-induced DNA damage, but it did not include endpoints measuring actual genetic damage. In the present study, we examined whether pre-exposure to ELF MF affects chemically induced DNA damage level, DNA repair rate, or micronucleus frequency in human SH-SY5Y neuroblastoma cells. METHODOLOGY/PRINCIPAL FINDINGS: Exposure to 50 Hz MF was conducted at 100 µT for 24 hours, followed by chemical exposure for 3 hours. The chemicals used for inducing DNA damage and subsequent micronucleus formation were menadione and methyl methanesulphonate (MMS. Pre-treatment with MF enhanced menadione-induced DNA damage, DNA repair rate, and micronucleus formation in human SH-SY5Y neuroblastoma cells. Although the results with MMS indicated similar effects, the differences were not statistically significant. No effects were observed after MF exposure alone. CONCLUSIONS: The results confirm our previous findings showing that pre-exposure to MFs as low as 100 µT alters cellular responses to menadione, and show that increased genotoxicity results from such interaction. The present findings also indicate that complementary data at several chronological points may be critical for understanding the MF effects on DNA damage, repair, and post-repair integrity of the genome.

Pre-exposure to 50 Hz magnetic fields modifies menadione-induced genotoxic effects in human SH-SY5Y neuroblastoma cells.

Science.gov (United States)

Luukkonen, Jukka; Liimatainen, Anu; Höytö, Anne; Juutilainen, Jukka; Naarala, Jonne

2011-03-23

Extremely low frequency (ELF) magnetic fields (MF) are generated by power lines and various electric appliances. They have been classified as possibly carcinogenic by the International Agency for Research on Cancer, but a mechanistic explanation for carcinogenic effects is lacking. A previous study in our laboratory showed that pre-exposure to ELF MF altered cancer-relevant cellular responses (cell cycle arrest, apoptosis) to menadione-induced DNA damage, but it did not include endpoints measuring actual genetic damage. In the present study, we examined whether pre-exposure to ELF MF affects chemically induced DNA damage level, DNA repair rate, or micronucleus frequency in human SH-SY5Y neuroblastoma cells. Exposure to 50 Hz MF was conducted at 100 µT for 24 hours, followed by chemical exposure for 3 hours. The chemicals used for inducing DNA damage and subsequent micronucleus formation were menadione and methyl methanesulphonate (MMS). Pre-treatment with MF enhanced menadione-induced DNA damage, DNA repair rate, and micronucleus formation in human SH-SY5Y neuroblastoma cells. Although the results with MMS indicated similar effects, the differences were not statistically significant. No effects were observed after MF exposure alone. The results confirm our previous findings showing that pre-exposure to MFs as low as 100 µT alters cellular responses to menadione, and show that increased genotoxicity results from such interaction. The present findings also indicate that complementary data at several chronological points may be critical for understanding the MF effects on DNA damage, repair, and post-repair integrity of the genome.

Conversion of Low Quality Waste Heat to Electric Power with Small-Scale Organic Rankine Cycle (ORC) Engine/Generator Technology

Science.gov (United States)

2016-08-01

efficiency by reducing energy consumption associated with electrical generation and reduces greenhouse gas emissions by increasing electrical generating...integrated system fuel economy test conditions This computation requires prediction of fuel consumption over baseline and integrated system load...EW-201251) Conversion of Low Quality Waste Heat to Electric Power with Small-Scale Organic Rankine Cycle (ORC) Engine/Generator Technology

In Shop Acceptance Test Report for the SY Farm Annulus Leak Detectors

International Nuclear Information System (INIS)

SMITH, S.G.

1999-01-01

The following test report was written for the SY tank farm annulus leak detectors. The test plan used was HNF-4546, Revision 1. The purpose of the test plan was to test the ENRAF series 854 ATG with SPU II card prior to installation. The test plan set various parameters and verifies the gauge and alarms functionality

PROF. ULRICH GERHARD LAUTS (1787— 1865). In sy studie „De ...

African Journals Online (AJOL)

Test

In sy studie „De beteekenis van 1813 voor Nederlands geestelijke beschaving"') het die .... af te lê. Daarna het hulle hul eed nog weer bevestig om trou te bly aan ..... L. 'n ver dedigende skrywe aan die Minister gestuur na aanleiding van 'n twis met die militêre geneesheer („Rijksarchief," Dept. van Marine. Prof. U. G..

Dibutyryl cyclic AMP induces differentiation of human neuroblastoma SH-SY5Y cells into a noradrenergic phenotype.

Science.gov (United States)

Kume, Toshiaki; Kawato, Yuka; Osakada, Fumitaka; Izumi, Yasuhiko; Katsuki, Hiroshi; Nakagawa, Takayuki; Kaneko, Shuji; Niidome, Tetsuhiro; Takada-Takatori, Yuki; Akaike, Akinori

2008-10-10

Dibutyryl cyclic AMP (dbcAMP) and retinoic acid (RA) have been demonstrated to be the inducers of morphological differentiation in SH-SY5Y cells, a human catecholaminergic neuroblastoma cell line. However, it remains unclear whether morphologically differentiated SH-SY5Y cells by these compounds acquire catecholaminergic properties. We focused on the alteration of tyrosine hydroxylase (TH) expression and intracellular content of noradrenaline (NA) as the indicators of functional differentiation. Three days treatment with dbcAMP (1mM) and RA (10microM) induced morphological changes and an increase of TH-positive cells using immunocytochemical analysis in SH-SY5Y cells. The percentage of TH-expressing cells in dbcAMP (1mM) treatment was larger than that in RA (10microM) treatment. In addition, dbcAMP increased intracellular NA content, whereas RA did not. The dbcAMP-induced increase in TH-expressing cells is partially inhibited by KT5720, a protein kinase A (PKA) inhibitor. We also investigated the effect of butyrate on SH-SY5Y cells, because dbcAMP is enzymatically degraded by intracellular esterase, thereby resulting in the formation of butyrate. Butyrate induced the increase of NA content at lower concentrations than dbcAMP, although the increase in TH-expressing cells by butyrate was smaller than that by dbcAMP. The dbcAMP (1mM)- and butyrate (0.3mM)-induced increase in NA content was completely suppressed by alpha-methyl-p-tyrosine (1mM), an inhibitor of TH. These results suggest that dbcAMP induces differentiation into the noradrenergic phenotype through both PKA activation and butyrate.

Curcumin Attenuated Bupivacaine-Induced Neurotoxicity in SH-SY5Y Cells Via Activation of the Akt Signaling Pathway.

Science.gov (United States)

Fan, You-Ling; Li, Heng-Chang; Zhao, Wei; Peng, Hui-Hua; Huang, Fang; Jiang, Wei-Hang; Xu, Shi-Yuan

2016-09-01

Bupivacaine is widely used for regional anesthesia, spinal anesthesia, and pain management. However, bupivacaine could cause neuronal injury. Curcumin, a low molecular weight polyphenol, has a variety of bioactivities and may exert neuroprotective effects against damage induced by some stimuli. In the present study, we tested whether curcumin could attenuate bupivacaine-induced neurotoxicity in SH-SY5Y cells. Cell injury was evaluated by examining cell viability, mitochondrial damage and apoptosis. We also investigated the levels of activation of the Akt signaling pathway and the effect of Akt inhibition by triciribine on cell injury following bupivacaine and curcumin treatment. Our findings showed that the bupivacaine treatment could induce neurotoxicity. Pretreatment of the SH-SY5Y cells with curcumin significantly attenuated bupivacaine-induced neurotoxicity. Interestingly, the curcumin treatment increased the levels of Akt phosphorylation. More significantly, the pharmacological inhibition of Akt abolished the cytoprotective effect of curcumin against bupivacaine-induced cell injury. Our data suggest that pretreating SH-SY5Y cells with curcumin provides a protective effect on bupivacaine-induced neuronal injury via activation of the Akt signaling pathway.

Soil structure interaction analysis for the Hanford Site 241-SY-101 double-shell waste storage tanks

International Nuclear Information System (INIS)

Giller, R.A.; Weiner, E.O.

1991-09-01

The 241-SY-101 tank is a double-shell waste storage tank buried in the 241-SY tank farm in the 200 West Area of the Hanford Site. This analysis addresses the effects of seismic soil-structure interaction on the tank structure and includes a parametric soil-structure interaction study addressing three configurations: two-dimensional soil structure, a two-dimensional structure-soil-structure, and a three-dimensional soil-structure interaction. This study was designed to determine an optimal method for addressing seismic-soil effects on underground storage tanks. The computer programs calculate seismic-soil pressures on the double-shell tank walls and and seismic acceleration response spectra in the tank. The results of this soil-structure interaction parametric study as produced by the computer programs are given in terms of seismic soil pressures and response spectra. The conclusions of this soil-structure interaction evaluation are that dynamically calculated soil pressures in the 241-SY-101 tank are significantly reduce from those using standard hand calculation methods and that seismic evaluation of underground double-shell waste storage tanks must consider soil-structure interaction effects in order to predict conservative structural response. Appendixes supporting this study are available in Volume 2 of this report

Hire a Milwaukee Engineer | College of Engineering & Applied Science

Science.gov (United States)

Electrical Engineering Instructional Laboratories Student Resources Industrial & Manufacturing Engineering Industrial & Manufacturing Engineering Academic Programs Industrial & Manufacturing Engineering Major Industrial & Manufacturing Engineering Minor Industrial & Manufacturing Engineering

UV time-dependent emission in SY Muscae

International Nuclear Information System (INIS)

Michalitsianos, A.G.; Kafatos, M.

1982-01-01

Ultraviolet spectra acquired with the International Ultraviolet Explorer (IUE) of SY Mus = HD 10036 on 20 September 1980 and 11 June 1981 indicate a substantial enhancement of UV emission over a nine month period. The general UV flux level appears to have increased by approximately one order of magnitude between the first and second observing epochs. The strong ultraviolet continuum evident throughout the entire IUE spectral range lambdalambda1200-3200 A on 11 June 1981 is closely approximated by a star with Tsub(eff) = 40,000 K, where previously on 20 September 1980 the continuum distribution presented a more complex structure that is possibly explained by a combination of thermal emission from an early type main sequence star, and nebular recombination emission (Michalitsianos et al. 1981). (Auth.)

Dual education and industrial cooperation in electrical engineering

Science.gov (United States)

Váradiné Szarka, A.

2016-11-01

Dual education in higher education is a new system in Hungary introduced by Mercedes Benz with cooperation of Kecskemet College. In the new system companies support certain number of students and provide them strong practical education in their field. Students applying successfully for dual education study together with non-dual students at the university, so they go through the same university courses as their non-dual colleagues, but while non-dual students’ academic year includes 2×14 weeks active semester and 2×6 weeks exam session, all over 40 weeks, dual students have 48 working weeks including study at the university and practicing at the company. The main question of the success which one is the most effective model to be applied. This paper summarises 2 models of dual education with their advantages and disadvantages and also it presents practical realization at the University of Debrecen with special attention to measurement and instrumentation. Dual education in BSc level electrical engineering course cooperates with 6 multinational companies of the region in four specialization. Dual education also has great impact to the modernisation of engineering education. Detailed study of dual education in field of instrumentation and measurement is provided in the paper.

Neurotoxicity of "ecstasy" and its metabolites in human dopaminergic differentiated SH-SY5Y cells.

Science.gov (United States)

Ferreira, Patrícia Silva; Nogueira, Tiago Bernandes; Costa, Vera Marisa; Branco, Paula Sério; Ferreira, Luísa Maria; Fernandes, Eduarda; Bastos, Maria Lourdes; Meisel, Andreas; Carvalho, Félix; Capela, João Paulo

2013-02-04

"Ecstasy" (3,4-methylenedioxymethamphetamine or MDMA) is a widely abused recreational drug, reported to produce neurotoxic effects, both in laboratory animals and in humans. MDMA metabolites can be major contributors for MDMA neurotoxicity. This work studied the neurotoxicity of MDMA and its catechol metabolites, α-methyldopamine (α-MeDA) and N-methyl-α-methyldopamine (N-Me-α-MeDA) in human dopaminergic SH-SY5Y cells differentiated with retinoic acid and 12-O-tetradecanoyl-phorbol-13-acetate. Differentiation led to SH-SY5Y neurons with higher ability to accumulate dopamine and higher resistance towards dopamine neurotoxicity. MDMA catechol metabolites were neurotoxic to SH-SY5Y neurons, leading to caspase 3-independent cell death in a concentration- and time-dependent manner. MDMA did not show a concentration- and time-dependent death. Pre-treatment with the antioxidant and glutathione precursor, N-acetylcysteine (NAC), resulted in strong protection against the MDMA metabolites' neurotoxicity. Neither the superoxide radical scavenger, tiron, nor the inhibitor of the dopamine (DA) transporter, GBR 12909, prevented the metabolites' toxicity. Cells exposed to α-MeDA showed an increase in intracellular glutathione (GSH) levels, which, at the 48 h time-point, was not dependent in the activity increase of γ-glutamylcysteine synthetase (γ-GCS), revealing a possible transient effect. Importantly, pre-treatment with buthionine sulfoximine (BSO), an inhibitor of γ-GCS, prevented α-MeDA induced increase in GSH levels, but did not augment this metabolite cytotoxicity. Even so, BSO pre-treatment abolished NAC protective effects against α-MeDA neurotoxicity, which were, at least partially, due to GSH de novo synthesis. Inversely, pre-treatment of cells with BSO augmented N-Me-α-MeDA-induced neurotoxicity, but only slightly affected NAC neuroprotection. In conclusion, MDMA catechol metabolites promote differential toxic effects to differentiated dopaminergic human SH-SY

Electrifying white biotechnology: engineering and economic potential of electricity-driven bio-production.

Science.gov (United States)

Harnisch, Falk; Rosa, Luis F M; Kracke, Frauke; Virdis, Bernardino; Krömer, Jens O

2015-03-01

The production of fuels and chemicals by electricity-driven bio-production (i.e., using electric energy to drive biosynthesis) holds great promises. However, this electrification of white biotechnology is particularly challenging to achieve because of the different optimal operating conditions of electrochemical and biochemical reactions. In this article, we address the technical parameters and obstacles to be taken into account when engineering microbial bioelectrochemical systems (BES) for bio-production. In addition, BES-based bio-production processes reported in the literature are compared against industrial needs showing that a still large gap has to be closed. Finally, the feasibility of BES bio-production is analysed based on bulk electricity prices. Using the example of lysine production from sucrose, we demonstrate that there is a realistic market potential as cost savings of 8.4 % (in EU) and 18.0 % (in US) could be anticipated, if the necessary yields can be obtained. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Application of diagnostic system for diesel engines in nuclear power plant

International Nuclear Information System (INIS)

Yoshinaga, Takeshi

2004-01-01

The diagnostic system for diesel engines makes a diagnosis of secular change and abnormal indications of diesel engines (DG) by combination of characteristic analysis of engine, lubricating oil, fuel oil, and cooling water. The principles of diagnostic system for DG, results of confirmation of the efficiency and the maintenance plan for DG in the Japan Atomic Power Company are described. DG in the company is classified to a safety device in order to supply the power source to the Emergency Core Cooling System etc., when the power source in the plant is lost, for example, at lightning struck. Characteristics of DG, outline of the diagnostic system for DG, diagnostic technologies such as engine signature analysis, chemical analysis of samples, temperature measurement, degradation mode of DG, and training in the company are stated. (S.Y.)

The Competence Readiness of the Electrical Engineering Vocational High School Teachers in Manado towards the ASEAN Economic Community Blueprint in 2025

OpenAIRE

Fid Jantje Tasiam; Djoko Kustono; Purnomo Purnomo; Hakkun Elmunsyah

2017-01-01

This paper presents the competence readiness of the electrical engineering vocational high school teachers in Manado towards ASEAN Economic Community blueprint in 2025. The objective of this study is to get the competencies readiness description of the electrical engineering vocational high school teachers in Manado towards ASEAN Economic Community blueprint in 2025. Method used quantitative and qualitative approach which the statistical analysis in quantitative and the inductive analysis use...

Improving the engineering-and-economical performance of ore-thermal electric furnaces in the smelting of silicomanganese

Science.gov (United States)

Kondrashov, V. P.; Pogrebisskiy, M. Ya; Lykov, A. G.; Rabinovich, V. L.; Bulgakov, A. S.

2018-02-01

Ways of increase of ore-heating electric furnaces, used for production of silicomanganese, engineering-and-economical performance are analyzed. Questions of data of the electric, thermal and technological modes of the furnace functioning collecting and processing for use in operation of an advanced control system of the furnace providing increase in technical and economic efficiency of technological process and an adaptability to quality of burden stock are considered.

Influence of thermodynamic mechanism of inter- facial adsorption on purifying air-conditioning engineering under intensification of electric field

Directory of Open Access Journals (Sweden)

Chen Yun-Yu

2016-12-01

Full Text Available As a kind of mass transfer process as well as the basis of separating and purifying mixtures, interfacial adsorption has been widely applied to fields like chemical industry, medical industry and purification engineering in recent years. Influencing factors of interfacial adsorption, in addition to the traditional temperature, intensity of pressure, amount of substance and concentration, also include external fields, such as magnetic field, electric field and electromagnetic field, etc. Starting from the point of thermodynamics and taking the Gibbs adsorption as the model, the combination of energy axiom and the first law of thermodynamics was applied to boundary phase, and thus the theoretical expression for the volume of interface absorption under electric field as well as the mathematical relationship between surface tension and electric field intensity was obtained. In addition, according to the obtained theoretical expression, the volume of interface absorption of ethanol solution under different electric field intensities and concentrations was calculated. Moreover, the mechanism of interfacial adsorption was described from the perspective of thermodynamics and the influence of electric field on interfacial adsorption was explained reasonably, aiming to further discuss the influence of thermodynamic mechanism of interfacial adsorption on purifying air-conditioning engineering under intensification of electric field.

One-step transvaginal three-dimensional hysterosalpingo-foam sonography (3D-HyFoSy) confirmation test for Essure® follow-up: a multicenter study.

Science.gov (United States)

Zizolfi, B; Lazzeri, L; Franchini, M; Di Spiezio Sardo, A; Nappi, C; Piccione, E; Exacoustos, C

2018-01-01

To evaluate, in patients who underwent Fallopian-tube sterilization by hysteroscopic insertion of an Essure® device, the feasibility and accuracy of three-dimensional (3D) transvaginal sonography (TVS) to check the position of the device and 3D hysterosalpingo-foam sonography (3D-HyFoSy) using contrast-enhanced gel foam to assess consequent tubal occlusion. This was a prospective multicenter study conducted from June 2012 to July 2014 in four Italian centers, which included 50 women who underwent hysteroscopic Essure microinsert placement in a total of 95 Fallopian tubes. Placement of the microinserts was performed in an outpatient setting following standard procedure recommendations. All patients underwent transvaginal 3D-HyFoSy and hysterosalpingography (HSG) approximately 12-14 weeks after the procedure. The position of the devices was first checked on 3D-TVS and classified according to specific criteria (Positions A, B, C and D). Then, 3D-HyFoSy with ExEm® gel foam as the ultrasound contrast agent was performed to confirm tubal occlusion by the absence of contrast agent within the tubes and/or around the ovaries. To evaluate the feasibility of 3D-HyFoSy, consecutive volume acquisitions were performed while injecting the gel foam. After sonographic evaluation, women underwent HSG to assess the success of sterilization, as standard methodology. Side effects and pain evoked during and after 3D-HyFoSy and HSG were evaluated using a numeric pain rating scale. On 3D-TVS, 10 devices (10.5%) were in Position A, two (2.1%) in Position B, 59 (62.1%) in Position C and 24 (25.3%) in Position D. During 3D-HyFoSy, tubal occlusion was observed in 89 of 95 tubes (93.7%). In the six cases in which the passage of the contrast was observed, one device (16.7%) was in Position B, one device (16.7%) in Position D and four devices (66.7%) were found to lie in Position C. Tubal patency was confirmed at HSG with a concordance rate of 100%. The mean pain score associated with 3D-HyFoSy

Design and implementation of an internet-based electrical engineering laboratory.

Science.gov (United States)

He, Zhenlei; Shen, Zhangbiao; Zhu, Shanan

2014-09-01

This paper describes an internet-based electrical engineering laboratory (IEE-Lab) with virtual and physical experiments at Zhejiang University. In order to synthesize the advantages of both experiment styles, the IEE-Lab is come up with Client/Server/Application framework and combines the virtual and physical experiments. The design and workflow of IEE-Lab are introduced. The analog electronic experiment is taken as an example to show Flex plug-in design, data communication based on XML (Extensible Markup Language), experiment simulation modeled by Modelica and control terminals' design. Crown Copyright © 2014. Published by Elsevier Ltd. All rights reserved.

Electrical Engineering in Los Alamos Neutron Science Center Accelerator

Energy Technology Data Exchange (ETDEWEB)

Silva, Michael James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2017-11-30

The field of electrical engineering plays a significant role in particle accelerator design and operations. Los Alamos National Laboratories LANSCE facility utilizes the electrical energy concepts of power distribution, plasma generation, radio frequency energy, electrostatic acceleration, signals and diagnostics. The culmination of these fields produces a machine of incredible potential with uses such as isotope production, neutron spallation, neutron imaging and particle analysis. The key isotope produced in LANSCE isotope production facility is Strontium-82 which is utilized for medical uses such as cancer treatment and positron emission tomography also known as PET scans. Neutron spallation is one of the very few methods used to produce neutrons for scientific research the other methods are natural decay of transuranic elements from nuclear reactors. Accelerator produce neutrons by accelerating charged particles into neutron dense elements such as tungsten imparting a neutral particle with kinetic energy, this has the benefit of producing a large number of neutrons as well as minimizing the waste generated. Utilizing the accelerator scientist can gain an understanding of how various particles behave and interact with matter to better understand the natural laws of physics and the universe around us.

Neurotoxicity Induced by Bupivacaine via T-Type Calcium Channels in SH-SY5Y Cells

Science.gov (United States)

Wen, Xianjie; Xu, Shiyuan; Liu, Hongzhen; Zhang, Quinguo; Liang, Hua; Yang, Chenxiang; Wang, Hanbing

2013-01-01

There is concern regarding neurotoxicity induced by the use of local anesthetics. A previous study showed that an overload of intracellular calcium is involved in the neurotoxic effect of some anesthetics. T-type calcium channels, which lower the threshold of action potentials, can regulate the influx of calcium ions. We hypothesized that T-type calcium channels are involved in bupivacaine-induced neurotoxicity. In this study, we first investigated the effects of different concentrations of bupivacaine on SH-SY5Y cell viability, and established a cell injury model with 1 mM bupivacaine. The cell viability of SH-SY5Y cells was measured following treatment with 1 mM bupivacaine and/or different dosages (10, 50, or 100 µM) of NNC 55-0396 dihydrochloride, an antagonist of T-type calcium channels for 24 h. In addition, we monitored the release of lactate dehydrogenase, cytosolic Ca2+ ([Ca2+]i), cell apoptosis and caspase-3 expression. SH-SY5Y cells pretreated with different dosages (10, 50, or 100 µM) of NNC 55-0396 dihydrochloride improved cell viability, reduced lactate dehydrogenase release, inhibited apoptosis, and reduced caspase-3 expression following bupivacaine exposure. However, the protective effect of NNC 55-0396 dihydrochloride plateaued. Overall, our results suggest that T-type calcium channels may be involved in bupivacaine neurotoxicity. However, identification of the specific subtype of T calcium channels involved requires further investigation. PMID:23658789

Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism

Directory of Open Access Journals (Sweden)

Song Ju-Xian

2012-01-01

Full Text Available Abstract Background Two active compounds, baicalein and its glycoside baicalin were found in the dried root of Scutellaria baicalensis Georgi, and reported to be neuroprotective in vitro and in vivo. This study aims to evaluate the protective effects of baicalein on the rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to parkinsonism. Methods Cell viability and cytotoxicity were determined by MTT assay. The degree of nuclear apoptosis was evaluated with a fluorescent DNA-binding probe Hoechst 33258. The production of reactive oxidative species (ROS and loss of mitochondrial membrane potential (ΔΨm were determined by fluorescent staining with DCFH-DA and Rhodanmine 123, respectively. The expression of Bax, Bcl-2, cleaved caspase-3 and phosphorylated ERK1/2 was determined by the Western blots. Results Baicalein significantly increased viability and decreased rotenone-induced death of SH-SY5Y cells in a dose-dependent manner. Pre- and subsequent co-treatment with baicalein preserved the cell morphology and attenuated the nuclear apoptotic characteristics triggered by rotenone. Baicalein antagonized rotenone-induced overproduction of ROS, loss of ΔΨm, the increased expression of Bax, cleaved caspase-3 and phosphorylated ERK1/2 and the decreased expression of Bcl-2. Conclusion The antioxidative effect, mitochondrial protection and modulation of anti-and pro-apoptotic proteins are related to the neuroprotective effects of baicalein against rotenone induced cell death in SH-SY5Y cells.

Neurotoxicity induced by bupivacaine via T-type calcium channels in SH-SY5Y cells.

Directory of Open Access Journals (Sweden)

Xianjie Wen

Full Text Available There is concern regarding neurotoxicity induced by the use of local anesthetics. A previous study showed that an overload of intracellular calcium is involved in the neurotoxic effect of some anesthetics. T-type calcium channels, which lower the threshold of action potentials, can regulate the influx of calcium ions. We hypothesized that T-type calcium channels are involved in bupivacaine-induced neurotoxicity. In this study, we first investigated the effects of different concentrations of bupivacaine on SH-SY5Y cell viability, and established a cell injury model with 1 mM bupivacaine. The cell viability of SH-SY5Y cells was measured following treatment with 1 mM bupivacaine and/or different dosages (10, 50, or 100 µM of NNC 55-0396 dihydrochloride, an antagonist of T-type calcium channels for 24 h. In addition, we monitored the release of lactate dehydrogenase, cytosolic Ca(2+ ([Ca2+]i, cell apoptosis and caspase-3 expression. SH-SY5Y cells pretreated with different dosages (10, 50, or 100 µM of NNC 55-0396 dihydrochloride improved cell viability, reduced lactate dehydrogenase release, inhibited apoptosis, and reduced caspase-3 expression following bupivacaine exposure. However, the protective effect of NNC 55-0396 dihydrochloride plateaued. Overall, our results suggest that T-type calcium channels may be involved in bupivacaine neurotoxicity. However, identification of the specific subtype of T calcium channels involved requires further investigation.

Safety evaluation for adding water to tank 101-SY

International Nuclear Information System (INIS)

Clinton, R.

1994-01-01

This document provides a new water limit for Tank 241-SY-101. The original limit was set at 9600 gallons. The new limit is now 20,000 gallons. There are various activities that require the use of additional water to the tank. The main activity is the removal of the temporary mixer pump. This requires a large amount of water which will exceed the original limit. Also, other activities such as flushing, adding a viscometer, and adding a void fraction meter requires additional water. The new limit safely incorporates these activities and allows room for more future activities

Safety equipment list for the 241-SY-101 RAPID mitigation project

Energy Technology Data Exchange (ETDEWEB)

MORRIS, K.L.

1999-06-29

This document provides the safety classification for the safety (safety class and safety RAPID Mitigation Project. This document is being issued as the project SEL until the supporting authorization basis documentation, this document will be superseded by the TWRS SEL (LMHC 1999), documentation istlralized. Upon implementation of the authorization basis significant) structures, systems, and components (SSCS) associated with the 241-SY-1O1 which will be updated to include the information contained herein.

Safety equipment list for the 241-SY-101 RAPID mitigation project

International Nuclear Information System (INIS)

Morris, K.L.

1999-01-01

This document provides the safety classification for the safety (safety class and safety RAPID Mitigation Project. This document is being issued as the project SEL until the supporting authorization basis documentation, this document will be superseded by the TWRS SEL (LMHC 1999), documentation istlralized. Upon implementation of the authorization basis significant) structures, systems, and components (SSCS) associated with the 241-SY-1O1 which will be updated to include the information contained herein

Electric and Plug-In Hybrid Electric Fleet Vehicle Testing | Transportation

Science.gov (United States)

Research | NREL Electric and Plug-In Hybrid Electric Fleet Vehicle Evaluations Electric and Plug-In Hybrid Electric Fleet Vehicle Evaluations How Electric and Plug-In Hybrid Electric Vehicles plugging the vehicle into an electric power source. PHEVs are powered by an internal combustion engine that

Palmitic acid induces neurotoxicity and gliatoxicity in SH-SY5Y human neuroblastoma and T98G human glioblastoma cells

Directory of Open Access Journals (Sweden)

Yee-Wen Ng

2018-04-01

Full Text Available Background Obesity-related central nervous system (CNS pathologies like neuroinflammation and reactive gliosis are associated with high-fat diet (HFD related elevation of saturated fatty acids like palmitic acid (PA in neurons and astrocytes of the brain. Methods Human neuroblastoma cells SH-SY5Y (as a neuronal model and human glioblastoma cells T98G (as an astrocytic model, were treated with 100–500 µM PA, oleic acid (OA or lauric acid (LA for 24 h or 48 h, and their cell viability was assessed by 3-(4,5-dimetylthiazol-2-yl-2,5-diphenyltetrazolium bromide (MTT assay. The effects of stable overexpression of γ-synuclein (γ-syn, a neuronal protein recently recognized as a novel regulator of lipid handling in adipocytes, and transient overexpression of Parkinson’s disease (PD α-synuclein [α-syn; wild-type (wt and its pathogenic mutants A53T, A30P and E46K] in SH-SY5Y and T98G cells, were also evaluated. The effects of co-treatment of PA with paraquat (PQ, a Parkinsonian pesticide, and leptin, a hormone involved in the brain-adipose axis, were also assessed. Cell death mode and cell cycle were analyzed by Annexin V/PI flow cytometry. Reactive oxygen species (ROS level was determined using 2′,7′-dichlorofluorescien diacetate (DCFH-DA assay and lipid peroxidation level was determined using thiobarbituric acid reactive substances (TBARS assay. Results MTT assay revealed dose- and time-dependent PA cytotoxicity on SH-SY5Y and T98G cells, but not OA and LA. The cytotoxicity was significantly lower in SH-SY5Y-γ-syn cells, while transient overexpression of wt α-syn or its PD mutants (A30P and E46K, but not A53T modestly (but still significantly rescued the cytotoxicity of PA in SH-SY5Y and T98G cells. Co-treatment of increasing concentrations of PQ exacerbated PA’s neurotoxicity. Pre-treatment of leptin, an anti-apoptotic adipokine, did not successfully rescue SH-SY5Y cells from PA-induced cytotoxicity—suggesting a mechanism of PA

Energy production systems engineering

CERN Document Server

Blair, Thomas Howard

2017-01-01

Energy Production Systems Engineering presents IEEE, Electrical Apparatus Service Association (EASA), and International Electrotechnical Commission (IEC) standards of engineering systems and equipment in utility electric generation stations. Electrical engineers that practice in the energy industry must understand the specific characteristics of electrical and mechanical equipment commonly applied to energy production and conversion processes, including the mechanical and chemical processes involved, in order to design, operate and maintain electrical systems that support and enable these processes. To aid this understanding, Energy Production Systems Engineeringdescribes the equipment and systems found in various types of utility electric generation stations. This information is accompanied by examples and practice problems. It also addresses common issues of electrical safety that arise in electric generation stations.

Structural analysis of multiport riser 5A installation on tank 241SY101

Energy Technology Data Exchange (ETDEWEB)

Strehlow, J.P.

1994-09-16

The Tank 101-SY multiport riser assembly in the 241-SY-101 waste tank will replace the existing 42 inch riser with four smaller ports. Each smaller port can be used independently to access the tank interior with equipment and instruments needed to mitigate the concentration of hydrogen in the tank. This document provides a design report on the structural evaluation of the multiport riser assembly as well as its anchorage. The multiport riser assembly is a steel structure installed directly above the 42-inch riser and sealed at the existing riser flange. The assembly is structurally supported by the concrete pad placed around the 42 inch riser. The multiport riser assembly will provide two 8-inch penetrations, one 12-inch penetration and one 24-inch penetration. Each penetration will have a shielding plate. These penetrations will be used to insert equipment such as a sonic probe into the tank. In addition to normal loads, non-reactor Safety Class 1 structures, systems and components are to withstand the effects of extreme environmental loads including Design Basis Earthquake (DBE), Design Basis Wind (DBW), Design Basis Flood, Volcanic Eruptions and other abnormal loads considered on a case by case basis. Non-reactor Safety Class 2, 3 and 4 structures, systems and components are those that are not Safety Class 1 and are respectively specified as onsite safety related, occupational safety related and non-safety related items. The 241-SY-101 tank is considered as a non-reactor Safety Class 1 structure. The multiport riser assembly is considered as a non-reactor Safety Class 2 structure since it serves to contain the radioactive and toxic materials under normal operating conditions. However, the pressure relief doors provided on the assembly are considered as Safety Class 1 structures.

Progress toward mitigation of flammable gas Tank 241-SY-101

International Nuclear Information System (INIS)

Lentsch, J.W.; Babad, H.; Hanson, C.E.; Kirch, N.W.

1994-01-01

The mixing pump installed in Hanford Site tank 241-SY-101 has been shown to be effective in releasing flammable gases in a controlled manner. This controlled release of gas prevents the accumulation and episodic release above flammable limits. More work needs to be done to optimize the pumping operation, and to evaluate the long-term effects of mixing so as to assure that no undesirable changes have occurred to the waste. Other alternative mitigation concepts are still being evaluated as a backup to mixing

Clustering analysis of questionnaire for Ph.D. studies in Electrical and Information Engineering in Europe

DEFF Research Database (Denmark)

Papadourakis, George M.; Christinaki, Eirini; Hatzi, Panagiota

2013-01-01

The ELLEIEC ERASMUS thematic network was running from October 2008 to September 2011. This project deals with several aspects linked to Lifelong Learning in Electrical and Information Engineering in Europe. Within this project, Task 4 is dedicated to “Implementation issues across EIE”. The idea...

Modulation of chemotherapy-induced cytotoxicity in SH-SY5Y neuroblastoma cells by caffeine and chlorogenic acid.

Science.gov (United States)

Hall, Susan; Anoopkumar-Dukie, Shailendra; Grant, Gary D; Desbrow, Ben; Lai, Richard; Arora, Devinder; Hong, Yinna

2017-06-01

Chemotherapy is an important treatment modality for malignancy but is limited by significant toxicity and it susceptibility to numerous drug interactions. While the interacting effects with medications are well known, there is limited evidence on the interaction with commonly consumed food and natural products. The aim of this study was to evaluate the bioactive constituents of coffee (caffeine and chlorogenic acid) on the cytotoxicity of doxorubicin, gemcitabine, and paclitaxel in vitro. Pretreatment with caffeine (100 nM and 10 μM) sensitized SH-SY5Y cells to doxorubicin-induced toxicity and increased apoptosis and sensitized PC3 cells to gemcitabine-induced toxicity. Pretreatment with 10 μM caffeine decreased total cell reactive oxygen species (ROS) production but increased mitochondrial ROS production. In contrast, caffeine (10 nM and 10 μM) protected cells against gemcitabine-induced toxicity and apoptosis. Similarly, 1 μM and 10 μM caffeine protected cells against paclitaxel-induced toxicity and mitochondrial ROS production. Chlorogenic acid had no effect on chemotherapy-induced toxicity in SH-SY5Y cells. In conclusion, this study provides preliminary evidence that caffeine, not chlorogenic acid, modulates the cytotoxicity of doxorubicin, gemcitabine, and paclitaxel in SH-SY5Y cells via different mechanisms.

Analysis of the Catecholaminergic Phenotype in Human SH-SY5Y and BE(2-M17 Neuroblastoma Cell Lines upon Differentiation.

Directory of Open Access Journals (Sweden)

Roberta Filograna

Full Text Available Human cell lines are often used to investigate cellular pathways relevant for physiological or pathological processes or to evaluate cell toxicity or protection induced by different compounds, including potential drugs. In this study, we analyzed and compared the differentiating activities of three agents (retinoic acid, staurosporine and 12-O-tetradecanoylphorbol-13-acetate on the human neuroblastoma SH-SY5Y and BE(2-M17 cell lines; the first cell line is largely used in the field of neuroscience, while the second is still poorly characterized. After evaluating their effects in terms of cell proliferation and morphology, we investigated their catecholaminergic properties by assessing the expression profiles of the major genes involved in catecholamine synthesis and storage and the cellular concentrations of the neurotransmitters dopamine and noradrenaline. Our results demonstrate that the two cell lines possess similar abilities to differentiate and acquire a neuron-like morphology. The most evident effects in SH-SY5Y cells were observed in the presence of staurosporine, while in BE(2-M17 cells, retinoic acid induced the strongest effects. Undifferentiated SH-SY5Y and BE(2-M17 cells are characterized by the production of both NA and DA, but their levels are considerably higher in BE(2-M17 cells. Moreover, the NAergic phenotype appears to be more pronounced in SH-SY5Y cells, while BE(2-M17 cells have a more prominent DAergic phenotype. Finally, the catecholamine concentration strongly increases upon differentiation induced by staurosporine in both cell lines. In conclusion, in this work the catecholaminergic phenotype of the human BE(2-M17 cell line upon differentiation was characterized for the first time. Our data suggest that SH-SY5Y and BE(2-M17 represent two alternative cell models for the neuroscience field.

Analysis of the Catecholaminergic Phenotype in Human SH-SY5Y and BE(2)-M17 Neuroblastoma Cell Lines upon Differentiation.

Science.gov (United States)

Filograna, Roberta; Civiero, Laura; Ferrari, Vanni; Codolo, Gaia; Greggio, Elisa; Bubacco, Luigi; Beltramini, Mariano; Bisaglia, Marco

2015-01-01

Human cell lines are often used to investigate cellular pathways relevant for physiological or pathological processes or to evaluate cell toxicity or protection induced by different compounds, including potential drugs. In this study, we analyzed and compared the differentiating activities of three agents (retinoic acid, staurosporine and 12-O-tetradecanoylphorbol-13-acetate) on the human neuroblastoma SH-SY5Y and BE(2)-M17 cell lines; the first cell line is largely used in the field of neuroscience, while the second is still poorly characterized. After evaluating their effects in terms of cell proliferation and morphology, we investigated their catecholaminergic properties by assessing the expression profiles of the major genes involved in catecholamine synthesis and storage and the cellular concentrations of the neurotransmitters dopamine and noradrenaline. Our results demonstrate that the two cell lines possess similar abilities to differentiate and acquire a neuron-like morphology. The most evident effects in SH-SY5Y cells were observed in the presence of staurosporine, while in BE(2)-M17 cells, retinoic acid induced the strongest effects. Undifferentiated SH-SY5Y and BE(2)-M17 cells are characterized by the production of both NA and DA, but their levels are considerably higher in BE(2)-M17 cells. Moreover, the NAergic phenotype appears to be more pronounced in SH-SY5Y cells, while BE(2)-M17 cells have a more prominent DAergic phenotype. Finally, the catecholamine concentration strongly increases upon differentiation induced by staurosporine in both cell lines. In conclusion, in this work the catecholaminergic phenotype of the human BE(2)-M17 cell line upon differentiation was characterized for the first time. Our data suggest that SH-SY5Y and BE(2)-M17 represent two alternative cell models for the neuroscience field.

Electric wiring domestic

CERN Document Server

Coker, A J

1992-01-01

Electric Wiring: Domestic, Tenth Edition, is a clear and reliable guide to the practical aspects of domestic electric wiring. Intended for electrical contractors, installation engineers, wiremen and students, its aim is to provide essential up to date information on modern methods and materials in a simple, clear, and concise manner. The main changes in this edition are those necessary to bring the work into line with the 16th Edition of the Regulations for Electrical Installations issued by the Institution of Electrical Engineers. The book begins by introducing the basic features of domestic

Tank 241-SY-101 surface level rise remediation test and evaluation plan for transfer system

International Nuclear Information System (INIS)

BAUER, R.E.

1999-01-01

The purpose of this testing and evaluation plan (TEP) is to provide the high level guidance on testing requirements for ensuring that the equipment and systems to be implemented for remediation of the SY-101 waste level rise USQ are effective

Engineering Topological Surface State of Cr-doped Bi2Se3 under external electric field

Science.gov (United States)

Zhang, Jian-Min; Lian, Ruqian; Yang, Yanmin; Xu, Guigui; Zhong, Kehua; Huang, Zhigao

2017-03-01

External electric field control of topological surface states (SSs) is significant for the next generation of condensed matter research and topological quantum devices. Here, we present a first-principles study of the SSs in the magnetic topological insulator (MTI) Cr-doped Bi2Se3 under external electric field. The charge transfer, electric potential, band structure and magnetism of the pure and Cr doped Bi2Se3 film have been investigated. It is found that the competition between charge transfer and spin-orbit coupling (SOC) will lead to an electrically tunable band gap in Bi2Se3 film under external electric field. As Cr atom doped, the charge transfer of Bi2Se3 film under external electric field obviously decreases. Remarkably, the band gap of Cr doped Bi2Se3 film can be greatly engineered by the external electric field due to its special band structure. Furthermore, magnetic coupling of Cr-doped Bi2Se3 could be even mediated via the control of electric field. It is demonstrated that external electric field plays an important role on the electronic and magnetic properties of Cr-doped Bi2Se3 film. Our results may promote the development of electronic and spintronic applications of magnetic topological insulator.

Human neuroblastoma SH-SY5Y cells show increased resistance to hyperthermic stress after differentiation, associated with elevated levels of Hsp72.

Science.gov (United States)

Cheng, Lesley; Smith, Danielle J; Anderson, Robin L; Nagley, Phillip

2011-01-01

Terminally differentiated neurones in the central nervous system need to be protected from stress. We ask here whether differentiation of progenitor cells to neurones is accompanied by up-regulation of Hsp72, with acquisition of enhanced thermotolerance. Human neuroblastoma SH-SY5Y cells were propagated in an undifferentiated form and subsequently differentiated into neurone-like cells. Thermotolerance tests were carried out by exposure of cells to various temperatures, monitoring nuclear morphology as index of cell death. Abundance of Hsp72 was measured in cell lysates by western immunoblotting. The differentiation of SH-SY5Y cells was accompanied by increased expression of Hsp72. Further, in both cell states, exposure to mild hyperthermic stress (43°C for 30 min) increased Hsp72 expression. After differentiation, SH-SY5Y cells were more resistant to hyperthermic stress compared to their undifferentiated state, correlating with levels of Hsp72. Stable exogenous expression of Hsp72 in SH-SY5Y cells (transfected line 5YHSP72.1, containing mildly elevated levels of Hsp72), led to enhanced resistance to hyperthermic stress. Hsp72 was found to be inducible in undifferentiated 5YHSP72.1 cells; such heat-treated cells displayed enhanced thermotolerance. Treatment of cells with KNK437, a suppressor of Hsp72 induction, resulted in acute thermosensitisation of all cell types tested here. Hsp72 has a major role in the enhanced hyperthermic resistance acquired during neuronal differentiation of SH-SY5Y cells. These findings model the requirement in intact organisms for highly differentiated neurones to be specially protected against thermal stress.

Conversion of Low Quality Waste Heat to Electric Power with Small-Scale Organic Rankine Cycle (ORC) Engine/Generator Technology

Science.gov (United States)

2016-06-01

block (expander) that allows gas expansion and converts the energy into rotational work, • an electric induction generator driven from the power block...is in the form of waste heat – thermal energy emitted via hot exhaust and heat removal systems associated with engine and other electric generator ...than 250 ºC), improves energy efficiency by reducing energy consumption associated with electrical generation and reduces greenhouse gas emissions

Electric power generation

International Nuclear Information System (INIS)

Pinske, J.D.

1981-01-01

Apart from discussing some principles of power industry the present text deals with the different ways of electric power generation. Both the conventional methods of energy conversion in heating and water power stations and the facilities for utilizing regenerative energy sources (sun, wind, ground heat, tidal power) are considered. The script represents the essentials of the lecture of the same name which is offered to the students of the special subject 'electric power engineering' at the Fachhochschule Hamburg. It does not require any special preliminary knowledge except for the general principles of electrical engineering. It is addressing students of electrical engineering who have passed their preliminary examination at technical colleges and universities. Moreover, it shall also be of use for engineers who want to obtain a quick survey of the structure and the operating characteristics of the extremely different technical methods of power generation. (orig.) [de

Fundamentals of electro-engineering I

International Nuclear Information System (INIS)

Rapsik, M.; Smola, M.; Bohac, M.; Mucha, M.

2004-01-01

This is the text-book of the fundamentals of electro-engineering. It contains the following chapters: (1) Selected terms in electro-engineering; (2) Fundamental electric values; (3) Energy and their transformations; (4) Water, hydro-energy and hydro-energetic potential of the Slovak Republic; (5) Nuclear power engineering; (6) Conventional thermal power plants; (7) Heating and cogeneration of electric power and heat production; (8) Equipment of electricity supply system; (9) Measurements in electro-engineering ; (10) Regulation of frequency and voltage, electric power quality

Safety Evaluation for Packaging 101-SY Hydrogen Mitigation Mixer Pump package

International Nuclear Information System (INIS)

Carlstrom, R.F.

1994-01-01

This Safety Evaluation for Packaging (SEP) provides analysis and considered necessary to approve a one-time transfer of the 101-SY Hydrogen Mitigation Mixer Pump (HMMP). This SEP will demonstrate that the transfer of the HMMP in a new shipping container will provide an equivalent degree of safety as would be provided by packages meeting US Department of Transportation (DOT)/US Nuclear Regulatory Commission (NRC) requirements. This fulfills onsite, transportation requirements implemented by WHC-CM-2-14

Safety Evaluation for Packaging 101-SY Hydrogen Mitigation Mixer Pump package

Energy Technology Data Exchange (ETDEWEB)

Carlstrom, R.F.

1994-10-05

This Safety Evaluation for Packaging (SEP) provides analysis and considered necessary to approve a one-time transfer of the 101-SY Hydrogen Mitigation Mixer Pump (HMMP). This SEP will demonstrate that the transfer of the HMMP in a new shipping container will provide an equivalent degree of safety as would be provided by packages meeting US Department of Transportation (DOT)/US Nuclear Regulatory Commission (NRC) requirements. This fulfills onsite, transportation requirements implemented by WHC-CM-2-14.

Enhanced Electrical Integration of Engineered Human Myocardium via Intramyocardial versus Epicardial Delivery in Infarcted Rat Hearts.

Directory of Open Access Journals (Sweden)

Kaytlyn A Gerbin

Full Text Available Cardiac tissue engineering is a promising approach to provide large-scale tissues for transplantation to regenerate the heart after ischemic injury, however, integration with the host myocardium will be required to achieve electromechanical benefits. To test the ability of engineered heart tissues to electrically integrate with the host, 10 million human embryonic stem cell (hESC-derived cardiomyocytes were used to form either scaffold-free tissue patches implanted on the epicardium or micro-tissue particles (~1000 cells/particle delivered by intramyocardial injection into the left ventricular wall of the ischemia/reperfusion injured athymic rat heart. Results were compared to intramyocardial injection of 10 million dispersed hESC-cardiomyocytes. Graft size was not significantly different between treatment groups and correlated inversely with infarct size. After implantation on the epicardial surface, hESC-cardiac tissue patches were electromechanically active, but they beat slowly and were not electrically coupled to the host at 4 weeks based on ex vivo fluorescent imaging of their graft-autonomous GCaMP3 calcium reporter. Histologically, scar tissue physically separated the patch graft and host myocardium. In contrast, following intramyocardial injection of micro-tissue particles and suspended cardiomyocytes, 100% of the grafts detected by fluorescent GCaMP3 imaging were electrically coupled to the host heart at spontaneous rate and could follow host pacing up to a maximum of 300-390 beats per minute (5-6.5 Hz. Gap junctions between intramyocardial graft and host tissue were identified histologically. The extensive coupling and rapid response rate of the human myocardial grafts after intramyocardial delivery suggest electrophysiological adaptation of hESC-derived cardiomyocytes to the rat heart's pacemaking activity. These data support the use of the rat model for studying electromechanical integration of human cardiomyocytes, and they

Electrical installation calculations advanced

CERN Document Server

Kitcher, Christopher

2013-01-01

All the essential calculations required for advanced electrical installation workThe Electrical Installation Calculations series has proved an invaluable reference for over forty years, for both apprentices and professional electrical installation engineers alike. The book provides a step-by-step guide to the successful application of electrical installation calculations required in day-to-day electrical engineering practiceA step-by-step guide to everyday calculations used on the job An essential aid to the City & Guilds certificates at Levels 2 and 3For apprentices and electrical installatio

A proteomic analysis of the interactions between poly(L-lactic acid nanofibers and SH-SY5Y neuronal-like cells

Directory of Open Access Journals (Sweden)

Ana Marote

2016-11-01

Full Text Available Poly (L-lactic acid (PLLA is a biodegradable and biocompatible polymer that has been put forward as a promising material for therapeutic approaches aiming to restore neuronal function. The topographic cues present in PLLA-based scaffolds, defined by the technique used in their preparation, have been shown to play a role on the cellular behavior of adherent cells. Even though this interaction has been shown to influence the regenerative output of the scaffold, there is a lack of studies addressing this response at the proteomic level. Hence, this work focuses on the effect of electrospun PLLA-based nanofibers on the proteome, cellular processes and signaling pathways of SH-SY5Y neuroblastoma cells. It also further explores how these molecular mediators might influence cell proliferation and differentiation upon in vitro culture. For that, mass spectrometry followed by bioinformatics analysis was firstly performed and further complemented with Western blot, cell viability and imaging assays. Results show that PLLA nanofibers differentially activate and inhibit specific cellular functions and signaling pathways related to cell division, apoptosis, actin remodeling, among others. These ultimately block cellular proliferation and induce morphological rearrangements through cytoskeleton remodeling, adaptations that turn cells more prone to differentiate. In synthesis, PLLA nanofibers shift the SH-SY5Y cells proteome towards a state more responsive to differentiation-inductive cues such as the retinoic acid. Unveiling cells responses to nanomaterials is an important step to increase the tools available for their manipulation and potentiate their use in neural tissue engineering. Further studies should be performed to compare the effects of other topographic cues on cellular behavior.

Effect of gear shift and engine start losses on control strategies for hybrid electric vehicles

NARCIS (Netherlands)

Ngo, V.; Hofman, T.; Steinbuch, M.; Serrarens, A.

2012-01-01

In this paper, energetic loss models in the events of shifting gear and starting engine in a parallel Hybrid Electric Vehicle equipped with an Automated Manual Transmission (AMT) will be introduced. The optimal control algorithm for the start-stop, power split and gear shift problem based on Dynamic

Application of the Stirling engine driven with cryogenic exergy of LNG (liquefied natural gas) for the production of electricity

International Nuclear Information System (INIS)

Szczygieł, Ireneusz; Stanek, Wojciech; Szargut, Jan

2016-01-01

LNG (liquefied natural gas) delivered by means of sea-ships is pressurized and then regasified before its introduction to the system of pipelines. The utilization of cryogenic exergy of LNG for electricity production without combustion of any its portion is analyzed. For the conversion of LNG cryogenic exergy into electricity, the Stirling engine is proposed to be applied. The theoretical thermodynamic model of Stirling engine has been applied. This model is used to investigate the influence of pinch temperature in heat exchangers, engine compression ratio and dead volumes ratios on the thermodynamic parameters of the Stirling engine. The results of simulation represent the input data for investigations of thermodynamic performance of the proposed system. In order to evaluate the thermodynamic performance of the proposed process, an exergy analysis has been applied. The exergy efficiency and influence of design and operational parameters on exergy losses are determined for each of the proposed system configurations. The obtained results represent the background for advanced exergy-based analyses, including thermo-ecological cost. - Highlights: • Application of Stirling engine in LNG regasification. • Thermodynamic model of Stirling engine for cryogenic exergy recovery is applied. • Sensitivity analysis of operational parameters on system behaviour is applied. • Exergy analysis is conducted.

Semisynthesis of SY-1 for investigation of breast cancer stem cell selectivity of C-ring-modified salinomycin analogues.

Science.gov (United States)

Huang, Xiaoli; Borgström, Björn; Månsson, Linda; Persson, Lo; Oredsson, Stina; Hegardt, Cecilia; Strand, Daniel

2014-07-18

Salinomycin, a naturally occurring polyether ionophore was recently found to selectively reduce the proportion of CD44(+)/CD24(-) cells, a phenotype associated with breast cancer stem cells. Subsequent studies from our group showed that chemical modification of the allylic C20 hydroxyl of salinomycin, located at the C-ring, can enhance the activity of derivatives against breast cancer cells over 5-fold compared to the native structure. Access to C-ring-modified salinomycin analogues is thus of interest from both a mechanistic and a synthetic perspective. Here, we report efficient strategies for gram scale synthesis of the natural product SY-1 (20-deoxy salinomycin), and a saturated analogue, 18,19-dihydro SY-1, for a comparative in vitro investigation of the biological profiles of these compounds with that of salinomycin. Across several assays, the deoxygenated structures required higher concentrations to elicit similar cellular responses to that of salinomycin. Similarly to salinomycin, SY-1 or 18,19-dihydro SY-1 treatment was found to reduce the proportion of CD44(+)/CD24(-) cells with essentially complete selectivity up to ∼IC25. Importantly, the proportion of CD44(+)/CD24(-) cells showed a pronounced U-shaped dose response curve for salinomycin and its derivatives, but not for paclitaxel. The concentration for maximum response in this assay followed differences in IC50 for salinomycin and its analogues, which emphasizes the importance of taking concentration dependence into account when comparing effects on the CD44(+)/CD24(-) phenotype. Small differences in the global conformation within the triad of compounds investigated together with differences in activity across assays emphasize the importance of substitution at C20 for the activity of salinomycin and its derivatives.

Comparison of ORC Turbine and Stirling Engine to Produce Electricity from Gasified Poultry Waste

Directory of Open Access Journals (Sweden)

Franco Cotana

2014-08-01

Full Text Available The Biomass Research Centre, section of CIRIAF, has recently developed a biomass boiler (300 kW thermal powered, fed by the poultry manure collected in a nearby livestock. All the thermal requirements of the livestock will be covered by the heat produced by gas combustion in the gasifier boiler. Within the activities carried out by the research project ENERPOLL (Energy Valorization of Poultry Manure in a Thermal Power Plant, funded by the Italian Ministry of Agriculture and Forestry, this paper aims at studying an upgrade version of the existing thermal plant, investigating and analyzing the possible applications for electricity production recovering the exceeding thermal energy. A comparison of Organic Rankine Cycle turbines and Stirling engines, to produce electricity from gasified poultry waste, is proposed, evaluating technical and economic parameters, considering actual incentives on renewable produced electricity.

AutoCAD electrical 2013 for electrical control designers

CERN Document Server

Tickoo, Sham; CADCIM Technologies

2013-01-01

The AutoCAD Electrical 2013 for Electrical Control Designers textbook has been written to assist the engineering students and the practicing designers learn the application of various AutoCAD Electrical tools and options for creating electrical control designs. After reading this textbook, the users will be able to create professional electrical-control drawings easily and effectively. Moreover, the users will be able to automate various control engineering tasks such as building circuits, numbering wires, creating bills of materials, and many more. The textbook takes the users across a wide spectrum of electrical control drawings through progressive examples and numerous illustrations and exercises, thereby making it an ideal guide for both the novice and the advanced users. Salient Features of the Textbook Consists of 14 chapters that are organized in a pedagogical sequence covering various tools and features of AutoCAD Electrical such as schematic drawings, parametric and non-parametric PLC modules, Circu...

Army symposium: Electrical energy engineering today; Wehrtechnisches Symposium: Moderne elektrische Energietechnik

Energy Technology Data Exchange (ETDEWEB)

Busse, H. (ed.) [Bundesakademie fuer Wehrverwaltung und Wehrtechnik, Mannheim (Germany). Fachgebiet Elektrotechnik und Elektroenergiewesen

2000-05-01

This symposium was held in Mannheim on May 20/21, 2000. All aspects of energy engineering were discussed, including electrochemical energy sources like accumulator batteries and fuel cells. The proceedings volume contains 26 papers which reflect the state of the art and current trends in electrical energy engineering in the German army. [German] Das Wehrtechnische Symposium 'Moderne elektrische Energietechnik' wurde von der Lehrabteilung Wehrtechnik der Bundesakademie fuer Wehrverwaltung und Wehrtechnik in Mannheim in der Zeit vom 20.05.-21.05.2000 durchgefuehrt. Das Programm enthaelt die aktuellen Themen der elektrischen Energietechnik. Die elektroschemischen Energiequellen (Batterien und Brennstoffzellen) wurden in das Programm integriert. Dadurch konnte das gesamte Spektrum der Energietechnik vielschichtig dargestellt und in der Diskussion unter z.T. sehr verschiedenen Gesichtspunkten beleuchtet werden. Die im vorliegenden Tagungsband abgedruckten 26 Skripte wurden weder gekuerzt noch ergaenzt. Sie zeigen insgesamt den aktuellen Stand und die erfolgversprechenden Entwicklungstendenzen der elektrischen Energietechnik in der Bundeswehr auf. (orig.)

Innovation in electric power technologies in 2009

International Nuclear Information System (INIS)

Ohfusa, Takahiro; Hayasaka, Eiji; Ino, Hiroyuki

2010-01-01

This is a report of the title by Tokyo Electric Power Company, Kansai Electric Power Co., Inc, Tohoku Electric Power and other nine enterprises in Japan. The outline is as follows. Tokyo Electric Power Company stated pipe thinning by the hot water based two-phase flow testing device, development of technologies for corrosion protection of nuclear reactor using titanium oxide, evaluation of fatigue damage by EBSD, and study of duty on the nuclear power plant. Japan Atomic Power Company (JAPC) stated the mechanism of decrease in exposure dose of the primary coolant system by zinc infusion, outline of Air Operated Valve Intelligent Diagnostic Analysis System (AVIDAS) and the grand packing system, development of SAPLS, the automatic search program of fuel position for design of PWR related core, development of compact containment water reactor (CCR) and FBR cycle system, investigation of the chain destruction of active fault under consideration of dynamic interaction of active faults and decommissioning of Tokai Nuclear Power Plant. Electric Power Development Company reported construction of the Oma Nuclear Power Plant, a future nuclear plant in Oma, Aomori. The reactor will be capable of using 100% MOX fuel core (MOX-ABWR). The operation will start November 2014. (S.Y.)

Fullerenes and fullerides - a kay to the advanced technologies of the 21st century in electrical engineering

International Nuclear Information System (INIS)

Trzaska, Z.

2001-01-01

Structures, properties, and methods of manufacturing of fullerenes as well as fullerides are described in the paper. These quite new materials known since beginning of the last decade represent the third crystallographic phase of the carbon and they belong to the nanostructural particles. They have been established during the past decade and awarded by the Nobel prize in 1996. The fullerene C 60 appears as a typical representative of this very large class od new nanostructural materials. Their possibilities and potential applications in the field of electrical engineering have been discussed. Because of many characteristic and useful properties of the fullerenes and fullerides their competition with respect to some materials frequently up-to-date used in the practice is proved. Examples of potential fields of applications, such as superconductors, electronic devices, effective measuring transducers of non-electric signals are also presented. Taking into account the high efficiency of the electric arc method which is widely used for manufacturing the fullerenes at the commercial level a prediction has been made that the dissemination of these new materials in the future industry creates a very good basis for a development of small and medium enterprises in the domain of electrical engineering. (author)

Advance of technological innovations of electric power in 2012

International Nuclear Information System (INIS)

Mayumi, Akihiko; Tanaka, Masanori; Takebe, Toshiro

2013-01-01

Twelve companies in Japan reported on the technological innovations in 2012. The Japan Atomic Power Company mainly studied five projects; (1) control of wall thinning of the secondary system in PWR by injection of molybdic acid, (2) application of pipe test method using electromagnetic acoustic resonance to existing equipment, (3) developed high performance Co-60 crud removal resin for Tsuruga Power Station Unit 2, (4) improvement of technology for safety of core in FBR, and (5) improvement of technology for coolant of FBR by dispersing nano-particles in liquid sodium metal. Tokyo Electric Power Company developed mainly three projects; (1) the support for the mental health care activities by industry protection staff at the Fukushima Daiichi and Daini Nuclear Power Plant, (2) laboratory test method using non-radioactive cesium for performance of decontamination reagent, and (3) decontamination effects estimation code (DeConEP). Hokuriku Electric Power Company reported the operations management measures in accordance with the safety enhancement measures to Shika nuclear power station. Other nine reports are published by Hokkaido Electric Power Co., Inc. Tohoku Electric Power Co., Inc. Chubu Electric Power Co., Inc., The Kansai Electric Power Co., Inc., The Chugoku Electric Power Co., Inc., Shikoku Electric Power Co., Inc., Kyushu Electric Power Co., Inc., Okinawa Electric Power Company Inc. and J-Power. (S.Y.)

Electric business in the world (the first)

International Nuclear Information System (INIS)

Takai, Mikio

2009-01-01

It consists of three chapters such as the energy and electricity in the world, the nuclear power generation in the world and each country. The first chapter includes the energy demand of each country in 2007 and for the future and estimation of electric power demand in the world, introduction of photovoltaic (PV) power generation, Emission Trading, and The Third Energy Package proposed by The European Commission in 2007. The second chapter states the conditions of nuclear power plants and construction plans in the world. The third chapter explains the nuclear power generation situation in US, England, France, German, Sweden, Korea, China, Russia and Eastern Europe. The consumption of energy in the world and each area, consumption of energy and increasing rate of each energy source, the change of electric power resources in the world, change of PV in each country, price of PV in EU under FIT system, the main regulations for emission trading in EU, and the nuclear power generation plants in the world on 31 December 2007 are illustrated. (S.Y.)

Electrical conduction in (Na0⋅ 125Bi0⋅ 125 Ba0⋅ 65Ca0⋅)(Nd0 ...

Indian Academy of Sciences (India)

Home; Journals; Bulletin of Materials Science; Volume 29; Issue 1. Electrical conduction in (Na0.125Bi0.125Ba0.65Ca0.1)(Nd0.065Ti0.87Nb0.065)O3 ceramic. Syed Mahboob G Prasad G S Kumar. Ceramics and Glasses Volume 29 Issue 1 February 2006 pp 35-41 ...

Electrical installation calculations basic

CERN Document Server

Kitcher, Christopher

2013-01-01

All the essential calculations required for basic electrical installation workThe Electrical Installation Calculations series has proved an invaluable reference for over forty years, for both apprentices and professional electrical installation engineers alike. The book provides a step-by-step guide to the successful application of electrical installation calculations required in day-to-day electrical engineering practice. A step-by-step guide to everyday calculations used on the job An essential aid to the City & Guilds certificates at Levels 2 and 3Fo

System design description for SY-101 hydrogen mitigation test project data acquisition and control system (DACS-1)

International Nuclear Information System (INIS)

Truitt, R.W.; Pounds, T.S.; Smith, S.O.

1994-01-01

This document describes the hardware subsystems of the data acquisition and control system (DACS) used in mitigation tests conducted on waste tank SY-101 at the Hanford Nuclear Reservation. The system was designed and implemented by Los Alamos National Laboratory (LANL) and supplied to Westinghouse Hanford Company (WHC). The mitigation testing uses a pump immersed in the waste tank, directed at certain angles and operated at different speeds and time durations. The SY-101 tank has experienced recurrent periodic gas releases of hydrogen, nitrous oxide, ammonia, and (recently discovered) methane. The hydrogen gas represents a danger, as some of the releases are in amounts above the lower flammability limit (LFL). These large gas releases must be mitigated. Several instruments have been added to the tank to monitor the gas compositions, the tank level, the tank temperature, and other parameters. A mixer pump has been developed to stir the tank waste to cause the gases to be released at a slow rate. It is the function of the DACS to monitor those instruments and to control the mixer pump in a safe manner. During FY93 and FY94 the mixer pump was installed with associated testing operations support equipment and a mitigation test project plan was implemented. These activities successfully demonstrated the mixer pump's ability to mitigate the SY-101 tank hydrogen gas hazard

[Resistance of Lactobacillus casei subsp. casei SY13 and Lactobacillus delbrueckii subsp. bulgaricus LJJ to reactive oxygen species].

Science.gov (United States)

Zhang, Shuwen; Lv, Jiaping; Menghe, Bilige; Zhang, Heping; Zhang, Liyu; Song, Jinhui; Wang, Zhifei

2009-02-01

We evaluated antioxidative effect of two antioxidative strains, isolated from the traditional fermented dairy products. Both intact cells and cell-free extract of Lactobacillus casei subsp. casei SY13 and Lactobacillus delbrueckii subsp. bulgaricus LJJ were used to study the inhibited effect of linoleic acid peroxidation, the ability of scavenging 1,1-diphenyl-2-picrylhydrazyl radical, hydroxyl radical, superoxide anion radical,the ability of tolerancing hydrogen peroxide and the chelating capacity of ferrous ion and reducting activity. Lactobacillus casei subsp. casei SY13 and Lactobacillus delbrueckii subsp. bulgaricus LJJ demonstrated highest inhibition on linoleic acid peroxidation by 62.95% and 66.16%, respectively. The cell-free extract showed excellent scavenging superoxide anion and hydroxyl radicals activity. However, the intact cells of Lactobacillus delbrueckii subsp. bulgaricus LJJ scavenging superoxide and hydroxyl radicals capacity were not detected. The intact cells of Lactobacillus casei subsp. casei SY13 and Lactobacillus delbrueckii subsp. bulgaricus LJJ on 1,1-diphenyl-2-picrylhydrazyl radical scavenging ability and chelating ferrous ion capacity were superior to cell-free extract. The highest reduced activety was equivalent to 305 micromol/L and 294 micromol/L L-cysteine. Two latobacilli strains had good antioxidant capacity. As potential probiotics, it can be used in future.

Acceptance test report, 241-SY-101 Flexible Receiver System, Phase 3 testing

International Nuclear Information System (INIS)

Ritter, G.A.

1995-01-01

This document summarizes the results of the phase 3 acceptance test of the 241-SY-101 Flexible Receiver System (FRS). The purpose of this acceptance test is to verify the sealing integrity of the FRS to ensure that the release of waste and aerosols will be minimized during the removal of the test mixer pump from Tank 241-SY-101. The FRS is one of six major components of the Equipment Removal System, which has been designed to retrieve, transport, and store the mixer pump. This acceptance test was performed at the 306E Facility in the 300 area from January 10, 1995 to January 17, 1995. The Phase 3 test consisted of two parts. Part one was a water leak test of the seal between the blast shield and mock load distribution frame (LDF) to ensure that significant contamination of the pump pit and waste interaction with the aluminum impact-limiting material under the LDF are prevented during the pump removal operation. The second part of this acceptance test was an air leak test of the assembled flexible receiver system. The purpose of this test was to verify that the release of hazardous aerosols will be minimized if the tank dome pressure becomes slightly positive during the decontamination of the mixer pump

Long-term security of electrical and control engineering equipment in nuclear power stations to withstand a loss of coolant accident

International Nuclear Information System (INIS)

Mueller, H.

1996-01-01

Electrical and control engineering equipment, which has to function even after many years of operation in the event of a fault in a saturated steam atmosphere of 160 C maximum, is essential in nuclear power stations in order to control a loss of coolant accident. The nuclear power station operators have, for this purpose, developed verification strategies for groups of components, by means of which it is ensured that the electrical and control engineering components are capable of dealing with a loss of coolant accident even at the end of their planned operating life. (orig.) [de

Experimental analysis of diffusion absorption refrigerator driven by electrical heater and engine exhaust gas

Directory of Open Access Journals (Sweden)

Mohamed Izzedine Serge ADJIBADE

2017-09-01

Full Text Available This work presents an experimental study of H20-NH3-H2 diffusion absorption refrigeration under two types of energy sources, i.e. the conventional electric energy from grid (electric and exhaust gas from internal combustion engine. Dynamic method is used to evaluate the behavior of the components of the system for both energy sources. Results obtained show that the performance of each component under different types of energy sources is almost coherent. For the generator, the electrical heater system requires more time to warm up, around three minutes, compared to the 40 s for system running with exhaust gas. For the evaporator, the decreasing rate is higher for the exhaust gas source and it took only about two hours to reach steady-state while for the electrical heat, the steady-state is reached after about seven hours of operation. For both energy sources, the evaporation temperature stabilizes to 3 °C and the minimum temperature to boil off ammonia is around 140 °C.

Neuroprotective Effect of Ginkgolide B on Bupivacaine-Induced Apoptosis in SH-SY5Y Cells

Science.gov (United States)

Li, Le; Zhang, Qing-guo; Lai, Lu-ying; Wen, Xian-jie; Zheng, Ting; Cheung, Chi-wai; Zhou, Shu-qin; Xu, Shi-yuan

2013-01-01

Local anesthetics are used routinely and effectively. However, many are also known to activate neurotoxic pathways. We tested the neuroprotective efficacy of ginkgolide B (GB), an active component of Ginkgo biloba, against ROS-mediated neurotoxicity caused by the local anesthetic bupivacaine. SH-SY5Y cells were treated with different concentrations of bupivacaine alone or following preincubation with GB. Pretreatment with GB increased SH-SY5Y cell viability and attenuated intracellular ROS accumulation, apoptosis, mitochondrial dysfunction, and ER stress. GB suppressed bupivacaine-induced mitochondrial depolarization and mitochondria complex I and III inhibition and increased cleaved caspase-3 and Htra2 expression, which was strongly indicative of activation of mitochondria-dependent apoptosis with concomitantly enhanced expressions of Grp78, caspase-12 mRNA, protein, and ER stress. GB also improved ultrastructural changes indicative of mitochondrial and ER damage induced by bupivacaine. These results implicate bupivacaine-induced ROS-dependent mitochondria, ER dysfunction, and apoptosis, which can be attenuated by GB through its antioxidant property. PMID:24228138

Composition, preparation, and gas generation results from simulated wastes of Tank 241-SY-101

International Nuclear Information System (INIS)

Bryan, S.A.; Pederson, L.R.

1994-08-01

This document reviews the preparation and composition of simulants that have been developed to mimic the wastes temporarily stored in Tank 241-SY-101 at Hanford. The kinetics and stoichiometry of gases that are generated using these simulants are also compared, considering the roles of hydroxide, chloride, and transition metal ions; the identities of organic constituents; and the effects of dilution, radiation, and temperature. Work described in this report was conducted for the Flammable Gas Safety Program at Pacific Northwest Laboratory, (a) whose purpose is to develop information that is necessary to mitigate potential safety hazards associated with waste tanks at the Hanford Site. The goal of this research and of related efforts at the Georgia Institute of Technology (GIT), Argonne National Laboratory (ANL), and Westinghouse Hanford Company (WHC) is to determine the thermal and thermal/radiolytic mechanisms by which flammable and other gases are produced in Hanford wastes, emphasizing those stored in Tank 241-SY-101. A variety of Tank 241-SY-101 simulants have been developed to date. The use of simulants in laboratory testing activities provides a number of advantages, including elimination of radiological risks to researchers, lower costs associated with experimentation, and the ability to systematically alter simulant compositions to study the chemical mechanisms of reactions responsible for gas generation. The earliest simulants contained the principal inorganic components of the actual waste and generally a single complexant such as N-(2-hydroxyethyl) ethylenediaminetriacetic acid (HEDTA) or ethylenediaminetriacetic acid (EDTA). Both homogeneous and heterogeneous compositional forms were developed. Aggressive core sampling and analysis activities conducted during Windows C and E provided information that was used to design new simulants that more accurately reflected major and minor inorganic components

Sharing data between mobile devices, connected vehicles, and infrastructure task 3: system requirements specifications (SyRS) final.

Science.gov (United States)

2016-07-14

This report describes the system requirements specifications (SyRS) for the use of mobile devices in a connected vehicle environment. Specifically, it defines the different types of requirements (functional, interface, performance, security, data, an...

Differentiated Human SH-SY5Y Cells Provide a Reductionist Model of Herpes Simplex Virus 1 Neurotropism.

Science.gov (United States)

Shipley, Mackenzie M; Mangold, Colleen A; Kuny, Chad V; Szpara, Moriah L

2017-12-01

Neuron-virus interactions that occur during herpes simplex virus (HSV) infection are not fully understood. Neurons are the site of lifelong latency and are a crucial target for long-term suppressive therapy or viral clearance. A reproducible neuronal model of human origin would facilitate studies of HSV and other neurotropic viruses. Current neuronal models in the herpesvirus field vary widely and have caveats, including incomplete differentiation, nonhuman origins, or the use of dividing cells that have neuropotential but lack neuronal morphology. In this study, we used a robust approach to differentiate human SH-SY5Y neuroblastoma cells over 2.5 weeks, producing a uniform population of mature human neuronal cells. We demonstrate that terminally differentiated SH-SY5Y cells have neuronal morphology and express proteins with subcellular localization indicative of mature neurons. These neuronal cells are able to support a productive HSV-1 infection, with kinetics and overall titers similar to those seen in undifferentiated SH-SY5Y cells and the related SK-N-SH cell line. However, terminally differentiated, neuronal SH-SY5Y cells release significantly less extracellular HSV-1 by 24 h postinfection (hpi), suggesting a unique neuronal response to viral infection. With this model, we are able to distinguish differences in neuronal spread between two strains of HSV-1. We also show expression of the antiviral protein cyclic GMP-AMP synthase (cGAS) in neuronal SH-SY5Y cells, which is the first demonstration of the presence of this protein in nonepithelial cells. These data provide a model for studying neuron-virus interactions at the single-cell level as well as via bulk biochemistry and will be advantageous for the study of neurotropic viruses in vitro IMPORTANCE Herpes simplex virus (HSV) affects millions of people worldwide, causing painful oral and genital lesions, in addition to a multitude of more severe symptoms such as eye disease, neonatal infection, and, in rare

Hybrid Turbine Electric Vehicle

Science.gov (United States)

Viterna, Larry A.

1997-01-01

Hybrid electric power trains may revolutionize today's ground passenger vehicles by significantly improving fuel economy and decreasing emissions. The NASA Lewis Research Center is working with industry, universities, and Government to develop and demonstrate a hybrid electric vehicle. Our partners include Bowling Green State University, the Cleveland Regional Transit Authority, Lincoln Electric Motor Division, the State of Ohio's Department of Development, and Teledyne Ryan Aeronautical. The vehicle will be a heavy class urban transit bus offering double the fuel economy of today's buses and emissions that are reduced to 1/10th of the Environmental Protection Agency's standards. At the heart of the vehicle's drive train is a natural-gas-fueled engine. Initially, a small automotive engine will be tested as a baseline. This will be followed by the introduction of an advanced gas turbine developed from an aircraft jet engine. The engine turns a high-speed generator, producing electricity. Power from both the generator and an onboard energy storage system is then provided to a variable-speed electric motor attached to the rear drive axle. An intelligent power-control system determines the most efficient operation of the engine and energy storage system.

Measuring Temporal Resolution (Release of Masking) with a Hughson-Westlake Up-Down Instead of a Békèsy-Tracking Procedure.

Science.gov (United States)

Rhebergen, Koenraad S; van Esch, Thamar E M; Dreschler, Wouter A

2015-06-01

A temporal resolution test in addition to the pure-tone audiogram may be of great clinical interest because of its relevance in speech perception and expected relevance in hearing aid fitting. Larsby and Arlinger developed an appropriate clinical test, but this test uses a Békèsy-tracking procedure for estimating masked thresholds in stationary and interrupted noise to assess release of masking (RoM) for temporal resolution. Generally the Hughson-Westlake up-down procedure is used in the clinic to measure the pure-tone thresholds in quiet. A uniform approach will facilitate clinical application and might be appropriate for RoM measurements as well. Because there is no golden standard for measuring the RoM in the clinic, we examine in the present study the Hughson-Westlake up-down procedure to measure the RoM and compare the results with the Békèsy-tracking procedure. The purpose of the current study was to examine the differences between a Békèsy-tracking procedure and the Hughson-Westlake up-down procedure for estimating masked thresholds in stationary and interrupted noise to assess RoM. RoM is assessed in eight normal-hearing (NH) and ten hearing-impaired (HI) listeners through both methods. Results from both methods are compared with each other and with predicted thresholds from a model. Wilcoxon signed-rank tests, paired t tests. Some differences between the two methods were found. We used a model to quantify the results of the two measurement procedures. The results of the Hughson-Westlake procedure were clearly better in agreement with the model than the results of the Békèsy-tracking procedure. Furthermore, the Békèsy-tracking procedure showed more spread in the results of the NH listeners than the Hughson-Westlake procedure. The Hughson-Westlake procedure seems to be an applicable alternative for measuring RoM for temporal resolution in the clinical audiological practice. American Academy of Audiology.

A Review of the Responses of Two- and Three-Dimensional Engineered Tissues to Electric Fields

Science.gov (United States)

Hronik-Tupaj, Marie

2012-01-01

The application of external biophysical signals is one approach to tissue engineering that is explored less often than more traditional additions of exogenous biochemical and chemical factors to direct cell and tissue outcomes. The study of bioelectromagnetism and the field of electrotherapeutics have evolved over the years, and we review biocompatible electric stimulation devices and their successful application to tissue growth. Specifically, information on capacitively coupled alternating current, inductively coupled alternating current, and direct current devices is described. Cell and tissue responses from the application of these devices, including two- and three-dimensional in vitro studies and in vivo studies, are reviewed with regard to cell proliferation, adhesion, differentiation, morphology, and migration and tissue function. The current understanding of cellular mechanisms related to electric stimulation is detailed. The advantages of electric stimulation are compared with those pf other techniques, and areas in which electric fields are used as an adjuvant therapy for healing and regeneration are discussed. PMID:22046979

Twice electric field poling for engineering multiperiodic Hex-PPLN microstructures

Science.gov (United States)

Pagliarulo, Vito; Gennari, Oriella; Rega, Romina; Mecozzi, Laura; Grilli, Simonetta; Ferraro, Pietro

2018-05-01

Satellite bulk ferroelectric domains were observed everywhere around the larger main inverted ferroelectric domains when a Twice Electric Field Poling (TEFP) process is applied on a z-cut lithium niobate substrate. TEFP approach can be very advantageous for engineering multiperiodic poled microstructures in ferroelectrics. In fact, it is very difficult in the experimental practice to avoid underpoling and/or overpoling when structures with different sizes are requested in the same crystal. TEFP was applied to photoresist patterned crystal with 100 μm period and then a second EP step, with a ten-times smaller periodicity of 10 μm, was accomplished on the same sample. The intriguing fact is that the shorter 10 μm pattern disappeared everywhere except that around the larger satellite ferroelectric domains. The formation of this double-periodicity in the reversed ferroelectric domains occurs very easily and in repeatedly way. We have experimentally investigated the formation of such HePPLN structures by an interference microscopy in digital holography (DH) modality. The reported results demonstrate the possibility of fabricating multi-periodic structures and open the way to investigate the possibility to achieve hierarchical PPLN structures by multiple subsequent electric poling processes.

CompTIA Security+ Deluxe Study Guide Exam SY0-301

CERN Document Server

Dulaney, Emmett

2011-01-01

Get a host of extras with this Deluxe version including a Security Administration Simulator!  Prepare for CompTIA's new Security+ exam SY0-301 with this Deluxe Edition of our popular CompTIA Security+ Study Guide, 5th Edition. In addition to the 100% coverage of all exam essentials and study tools you'll find in the regular study guide, the Deluxe Edition gives you over additional hands-on lab exercises and study tools, three additional practice exams, author videos, and the exclusive Security Administration simulator. This book is a CompTIA Recommended product. Provides 100% coverage of all e

Emulsion-core and polyelectrolyte-shell nanocapsules: biocompatibility and neuroprotection against SH-SY5Y cells

International Nuclear Information System (INIS)

Piotrowski, Marek; Szczepanowicz, Krzysztof; Jantas, Danuta; Leśkiewicz, Monika; Lasoń, Władysław; Warszyński, Piotr

2013-01-01

The emulsion-core and polyelectrolyte-coated nanocapsules, designed as water-insoluble neuroprotective drug delivery system, were synthesized using layer-by-layer saturation method. The isopropyl myristate was used as oil phase and docusate sodium salt as emulsifier. For the polyelectrolyte shell preparation, synthetic polyelectrolytes, cationic (PDADMAC, PAH, and PLL) and anionic (PGA) were used. The particle size and zeta potential of nanocapsules were characterized by the dynamic light scattering. The average size of synthesized nanocapsules ranged from ∼80 to ∼100 nm. Zeta potential values ranged from less than approximately −30 mV for the polyanion layers to greater than approximately +30 mV for the polycation layers. Biocompatibilities of the synthesized nanocarriers were evaluated against SH-SY5Y human neuroblastoma cells using various biochemical assays. The results obtained show that synthesized nanocapsules coated with PLL and PGA were nontoxic to SH-SY5Y cells, and they were used as nanocarriers for model neuroprotective drug (a calpain inhibitor MDL 28170). The neuroprotective action of the encapsulated MDL 28170 against hydrogen peroxide-induced oxidative stress cytotoxicity was evaluated in the same cell line. The results showed that nanoencapsulated form of MDL 28170 were biocompatible and protected SH-SY5Y cells against the H 2 O 2 (0.5 mM/24 h)-induced damage in 20–40 times lower concentrations than those of the same drug added directly to the culture medium. These data suggest that the nanoscale carriers of neuroprotective drugs might serve as novel promising therapeutic agents for oxidative stress-related neurodegenerative processes

Emulsion-core and polyelectrolyte-shell nanocapsules: biocompatibility and neuroprotection against SH-SY5Y cells

Energy Technology Data Exchange (ETDEWEB)

Piotrowski, Marek, E-mail: ncpiotro@cyf-kr.edu.pl; Szczepanowicz, Krzysztof [Polish Academy of Sciences, Jerzy Haber Institute of Catalysis and Surface Chemistry (Poland); Jantas, Danuta; Leśkiewicz, Monika; Lasoń, Władysław [Polish Academy of Sciences, Institute of Pharmacology (Poland); Warszyński, Piotr [Polish Academy of Sciences, Jerzy Haber Institute of Catalysis and Surface Chemistry (Poland)

2013-11-15

The emulsion-core and polyelectrolyte-coated nanocapsules, designed as water-insoluble neuroprotective drug delivery system, were synthesized using layer-by-layer saturation method. The isopropyl myristate was used as oil phase and docusate sodium salt as emulsifier. For the polyelectrolyte shell preparation, synthetic polyelectrolytes, cationic (PDADMAC, PAH, and PLL) and anionic (PGA) were used. The particle size and zeta potential of nanocapsules were characterized by the dynamic light scattering. The average size of synthesized nanocapsules ranged from ∼80 to ∼100 nm. Zeta potential values ranged from less than approximately −30 mV for the polyanion layers to greater than approximately +30 mV for the polycation layers. Biocompatibilities of the synthesized nanocarriers were evaluated against SH-SY5Y human neuroblastoma cells using various biochemical assays. The results obtained show that synthesized nanocapsules coated with PLL and PGA were nontoxic to SH-SY5Y cells, and they were used as nanocarriers for model neuroprotective drug (a calpain inhibitor MDL 28170). The neuroprotective action of the encapsulated MDL 28170 against hydrogen peroxide-induced oxidative stress cytotoxicity was evaluated in the same cell line. The results showed that nanoencapsulated form of MDL 28170 were biocompatible and protected SH-SY5Y cells against the H{sub 2}O{sub 2} (0.5 mM/24 h)-induced damage in 20–40 times lower concentrations than those of the same drug added directly to the culture medium. These data suggest that the nanoscale carriers of neuroprotective drugs might serve as novel promising therapeutic agents for oxidative stress-related neurodegenerative processes.

Integrated Studies of Electric Propulsion Engines during Flights in the Earth's Ionosphere

Science.gov (United States)

Marov, M. Ya.; Filatyev, A. S.

2018-03-01

Fifty years ago, on October 1, 1966, the first Yantar satellite laboratory with a gas plasma-ion electric propulsion was launched into orbit as part of the Yantar Soviet space program. In 1966-1971, the program launched a total of four laboratories with thrusters operating on argon, nitrogen, and air with jet velocities of 40, 120, and 140 km/s, respectively. These space experiments were the first to demonstrate the long-term stable operation of these thrusters, which exceed chemical rocket engines in specific impulse by an order of magnitude and provide effective jet charge compensation, under the conditions of a real flight at altitudes of 100-400 km. In this article, we have analyzed the potential modern applications of the scientific results obtained by the Yantar space program for the development of air-breathing electric propulsion that ensure the longterm operation of spacecraft in very low orbits.

Differential Expression of Tyrosine Hydroxylase Protein and Apoptosis-Related Genes in Differentiated and Undifferentiated SH-SY5Y Neuroblastoma Cells Treated with MPP+

OpenAIRE

Khwanraj, Kawinthra; Phruksaniyom, Chareerut; Madlah, Suriyat; Dharmasaroja, Permphan

2015-01-01

The human neuroblastoma SH-SY5Y cell line has been used as a dopaminergic cell model for Parkinson's disease research. Whether undifferentiated or differentiated SH-SY5Y cells are more suitable remains controversial. This study aims to evaluate the expression of apoptosis-related mRNAs activated by MPP+ and evaluate the differential expression of tyrosine hydroxylase (TH) in undifferentiated and retinoic acid- (RA-) induced differentiated cells. The western blot results showed a gradual decre...

Overexpression of tissue-nonspecific alkaline phosphatase increases the expression of neurogenic differentiation markers in the human SH-SY5Y neuroblastoma cell line.

Science.gov (United States)

Graser, Stephanie; Mentrup, Birgit; Schneider, Doris; Klein-Hitpass, Ludger; Jakob, Franz; Hofmann, Christine

2015-10-01

Patients suffering from the rare hereditary disease hypophosphatasia (HPP), which is based on mutations in the ALPL gene, tend to develop central nervous system (CNS) related issues like epileptic seizures and neuropsychiatric illnesses such as anxiety and depression, in addition to well-known problems with the mineralization of bones and teeth. Analyses of the molecular role of tissue-nonspecific alkaline phosphatase (TNAP) in transgenic SH-SY5Y(TNAPhigh) neuroblastoma cells compared to SH-SY5Y(TNAPlow) cells indicate that the enzyme influences the expression levels of neuronal marker genes like RNA-binding protein, fox-1 homolog 3 (NEUN) and enolase 2, gamma neuronal (NSE) as well as microtubule-binding proteins like microtubule-associated protein 2 (MAP2) and microtubule-associated protein tau (TAU) during neurogenic differentiation. Fluorescence staining of SH-SY5Y(TNAPhigh) cells reveals TNAP localization throughout the whole length of the developed projection network and even synapsin Ι co-localization with strong TNAP signals at some spots at least at the early time points of differentiation. Additional immunocytochemical staining shows higher MAP2 expression in SH-SY5Y(TNAPhigh) cells and further a distinct up-regulation of tau and MAP2 in the course of neurogenic differentiation. Interestingly, transgenic SH-SY5Y(TNAPhigh) cells are able to develop longer cellular processes compared to control cells after stimulation with all-trans retinoic acid (RA). Current therapies for HPP prioritize improvement of the bone phenotype. Unraveling the molecular role of TNAP in extraosseous tissues, like in the CNS, will help to improve treatment strategies for HPP patients. Taking this rare disease as a model may also help to dissect TNAP's role in neurodegenerative diseases and even improve future treatment of common pathologies. Copyright © 2015 Elsevier Inc. All rights reserved.

Pregnancy outcome after hystero-salpingo-contrast-sonography (HyCoSy versus hysterosalpingography (HSG using different contrast media

Directory of Open Access Journals (Sweden)

Emad M. Siam

2011-12-01

Conclusion: The pregnancy rates after performing HyCoSy using the proposed homogenously mixed saline and water are nearly the same as those following HSG using different contrast media with inherent advantage of avoiding exposure to radiation.

Battery systems engineering

CERN Document Server

Rahn, Christopher D

2012-01-01

A complete all-in-one reference on the important interdisciplinary topic of Battery Systems Engineering Focusing on the interdisciplinary area of battery systems engineering, this book provides the background, models, solution techniques, and systems theory that are necessary for the development of advanced battery management systems. It covers the topic from the perspective of basic electrochemistry as well as systems engineering topics and provides a basis for battery modeling for system engineering of electric and hybrid electric vehicle platforms. This original

Ras-MAPK signaling in differentiating SH-SY5Y human neuroblastoma cells

OpenAIRE

Olsson, Anna-Karin

2000-01-01

Neuroblastoma is a malignant childhood cancer, originating from sympathetic neuroblasts of the peripheral nervous system. Neuroblastoma is a heterogenous group of tumours, while some are highly malignant others can spontaneosly mature into a more benign form or regress. Less than half of the patients survive and this statistics has improved only modestly over the past 20 years. SH-SY5Y is a human neuroblastoma cell line established from a highly malignant tumour. The cells have retained a ca...

Simulation models of a drive with an asynchronous electric engine for students of electrical engineering faculties

Directory of Open Access Journals (Sweden)

Romanenko N. G.

2017-10-01

Full Text Available the application of virtual laboratories will allow to show different transition processes, as well as to carry out experiments that are very expensive in real electrical machines’ labs, for example, to calculate the energy costs in electric drives. Models of non-regulation asynchronous drive and frequency-regulated asynchronous electric drive are examined in this article. The author has calculated and compared the energy losses of these systems with various types of loads and this lets us to evaluate work processes of many technical devices.

Evaluation Program on the Implementation of Industrial Apprenticeship (Prakerin) in Electrical Engineering

Science.gov (United States)

Maulana, I.; Sumarto; Nurafiati, P.; Puspita, R. H.

2018-02-01

This research aims to find out the evaluation program of the Industrial apprenticeship (Prakerin) in electrical engineering. This research includes on four variables of CIPP. (1). Context (a). programme planning (b). design. (2). Input (a). readiness of students (b). performance of vocational education teachers (c). Facilities and infrastructure, (3). process (a). performance students (b). performance mentors, (4). Product (a). readiness of student work. This research is a type of program evaluation research with Stake model approach. Data collection methods used are questionnaires with closed questions and frequently asked questions.

The Secretome of Bone Marrow and Wharton Jelly Derived Mesenchymal Stem Cells Induces Differentiation and Neurite Outgrowth in SH-SY5Y Cells

OpenAIRE

Ana O. Pires; Andreia Neves-Carvalho; Nuno Sousa; António J. Salgado

2014-01-01

The goal of this study was to determine and compare the effects of the secretome of mesenchymal stem cells (MSCs) isolated from human bone-marrow (BMSCs) and the Wharton jelly surrounding the vein and arteries of the umbilical cord (human umbilical cord perivascular cells (HUCPVCs)) on the survival and differentiation of a human neuroblastoma cell line (SH-SY5Y). For this purpose, SH-SY5Y cells were differentiated with conditioned media (CM) from the MSCs populations referred above. Retinoic ...

Selection of strategy for electric power engineering development in Russia for period up to 2015

International Nuclear Information System (INIS)

Khainson, Ya.I.; Mirkovskaya, R.E.; Artem'eva, N.Yu.

1993-01-01

The result of studies, in which an attempt to select a number of real versions for development of electric power engineering for the period up to 2015, as well as to evaluate, compare and select essentially stable trends is made, are discussed. It is shown that these trends remain actual even under market economics conditions. The necessity is emphasized for creation and introduction of new generation of units and electric power plants ecologically clean, reliable and operating in wide unit capacity range. Special attention should be paid to creation of new types of NPPs, underground NPPs as well as low-and intermediate-capacity NPPs necessary for many regions of the country

Correlation between electrical, mechanical and chemical properties of fresh and used aircraft engine oils

Science.gov (United States)

Gajewski, Juliusz B.; Głogowski, Marek J.; Paszkowski, Maciej; Czarnik-Matusewicz, Bogusława

2011-06-01

In this paper the results are presented of measurements of electrical, mechanical and chemical properties of fresh and used aircraft engine oils. Oils were used in a four-stroke aircraft engine and their samples were taken after the 50-hour work of the engine. The resistivity, permittivity and viscosity of oils were measured as a function of temperature. Additionally, some measurements of the absorbance spectra and size of particles contained in the oils were carried out. The significant reduction in the resistivity of the used Total oil was observed. The relative permittivity of both used oils was slightly increased. The oil's relative viscosity depends on temperature of oil and given time that elapsed from the very first moment when the shear force was applied in a rheometer. The results obtained allowed one to identify more precisely the chemical and physico-chemical interactions occurring in the tested samples, as compared with a typical infrared spectroscopy.

Correlation between electrical, mechanical and chemical properties of fresh and used aircraft engine oils

International Nuclear Information System (INIS)

Gajewski, Juliusz B; Glogowski, Marek J; Paszkowski, Maciej; Czarnik-Matusewicz, Boguslawa

2011-01-01

In this paper the results are presented of measurements of electrical, mechanical and chemical properties of fresh and used aircraft engine oils. Oils were used in a four-stroke aircraft engine and their samples were taken after the 50-hour work of the engine. The resistivity, permittivity and viscosity of oils were measured as a function of temperature. Additionally, some measurements of the absorbance spectra and size of particles contained in the oils were carried out. The significant reduction in the resistivity of the used Total oil was observed. The relative permittivity of both used oils was slightly increased. The oil's relative viscosity depends on temperature of oil and given time that elapsed from the very first moment when the shear force was applied in a rheometer. The results obtained allowed one to identify more precisely the chemical and physico-chemical interactions occurring in the tested samples, as compared with a typical infrared spectroscopy.

Analysis of the 241SY101 pump removal trailer and the 241SY101 strongback

International Nuclear Information System (INIS)

Coverdell, B.L.

1995-09-01

The purpose of the calculations contained in the attached appendix is to determine the vibrational stability of the following combination (The Combination); shipping container, strongback and trailer. The vibrational stability of The Combination will be determined with the shipping container and strongback in the upright position. If the natural frequency of The Combination coincides with the input frequency and no damping is present, resonance will occur. The result of this is that the natural frequency of the Combination must be calculated as well as the input frequency. The input frequency in this case is caused by wind. Due to their geometrical complexity the upper and lower hydraulic clevises were analyzed for structural adequacy by using finite-element analysis (FEA). The FEA software COSMOS/M version 1.70 was used to model the upper and lower hydraulic clevis. All designs are in accordance with Standard Architectural-Civil Design Criteria, Design Loads for Facilities (DOE-RL 1989) and are safety class 3. The design and fabrication of each component is in accordance with American Institute of Steel Construction, Manual of Steel Construction, (AISC, 1989). The analyses contained in this document reflects the as-built condition of the 241SY101 hydraulic trailer

Dielectric materials for electrical engineering

CERN Document Server

Martinez-Vega, Juan

2013-01-01

Part 1 is particularly concerned with physical properties, electrical ageing and modeling with topics such as the physics of charged dielectric materials, conduction mechanisms, dielectric relaxation, space charge, electric ageing and life end models and dielectric experimental characterization. Part 2 concerns some applications specific to dielectric materials: insulating oils for transformers, electrorheological fluids, electrolytic capacitors, ionic membranes, photovoltaic conversion, dielectric thermal control coatings for geostationary satellites, plastics recycling and piezoelectric poly

Canadian conference on electrical and computer engineering proceedings. Congres canadien en genie electrique et informatique

Energy Technology Data Exchange (ETDEWEB)

Bhargava, V K [ed.

1993-01-01

A conference was held on the subject of electrical and computer engineering. Papers were presented on the subjects of artificial intelligence, video, signal processing, radar, power electronics, neural networks, control, computer systems, transportation electronics, software tools, error control coding, electrothermal phenomena, performance evaluation of computer systems, wireless communication, satellite communication, very large scale integration, parallel processing, pattern recognition, telephony, graphs and algorithms, multimedia, broadcast systems, remote sensing, computer networks, modulation and coding, robotics, computer architecture, spread spectrum, image processing, microwave circuits, biomedical engineering, specification and verification, image restoration, communications networks, computer-aided design, drives, energy systems, expert systems, and optics. Separate abstracts have been prepared for 56 papers from the conference.

Probabilistic safety assessment for Hanford high-level waste tank 241-SY-101

Energy Technology Data Exchange (ETDEWEB)

MacFarlane, D.R.; Bott, T.F.; Brown, L.F.; Stack, D.W. [Los Alamos National Lab., NM (United States); Kindinger, J.; Deremer, R.K.; Medhekar, S.R.; Mikschl, T.J. [PLG, Inc., Newport Beach, CA (United States)

1994-05-01

Los Alamos National Laboratory (Los Alamos) is performing a comprehensive probabilistic safety assessment (PSA), which will include consideration of external events for the 18 tank farms at the Hanford Site. This effort is sponsored by the Department of Energy (DOE/EM, EM-36). Even though the methodology described herein will be applied to the entire tank farm, this report focuses only on the risk from the weapons-production wastes stored in tank number 241-SY-101, commonly known as Tank 101-SY, as configured in December 1992. This tank, which periodically releases ({open_quotes}burps{close_quotes}) a gaseous mixture of hydrogen, nitrous oxide, ammonia, and nitrogen, was analyzed first because of public safety concerns associated with the potential for release of radioactive tank contents should this gas mixture be ignited during one of the burps. In an effort to mitigate the burping phenomenon, an experiment is being conducted in which a large pump has been inserted into the tank to determine if pump-induced circulation of the tank contents will promote a slow, controlled release of the gases. At the Hanford Site there are 177 underground tanks in 18 separate tank farms containing accumulated liquid/sludge/salt cake radioactive wastes from 50 yr of weapons materials production activities. The total waste volume is about 60 million gal., which contains approximately 120 million Ci of radioactivity.

Probabilistic safety assessment for Hanford high-level waste tank 241-SY-101

International Nuclear Information System (INIS)

MacFarlane, D.R.; Bott, T.F.; Brown, L.F.; Stack, D.W.; Kindinger, J.; Deremer, R.K.; Medhekar, S.R.; Mikschl, T.J.

1994-05-01

Los Alamos National Laboratory (Los Alamos) is performing a comprehensive probabilistic safety assessment (PSA), which will include consideration of external events for the 18 tank farms at the Hanford Site. This effort is sponsored by the Department of Energy (DOE/EM, EM-36). Even though the methodology described herein will be applied to the entire tank farm, this report focuses only on the risk from the weapons-production wastes stored in tank number 241-SY-101, commonly known as Tank 101-SY, as configured in December 1992. This tank, which periodically releases (open-quotes burpsclose quotes) a gaseous mixture of hydrogen, nitrous oxide, ammonia, and nitrogen, was analyzed first because of public safety concerns associated with the potential for release of radioactive tank contents should this gas mixture be ignited during one of the burps. In an effort to mitigate the burping phenomenon, an experiment is being conducted in which a large pump has been inserted into the tank to determine if pump-induced circulation of the tank contents will promote a slow, controlled release of the gases. At the Hanford Site there are 177 underground tanks in 18 separate tank farms containing accumulated liquid/sludge/salt cake radioactive wastes from 50 yr of weapons materials production activities. The total waste volume is about 60 million gal., which contains approximately 120 million Ci of radioactivity

Acceptance test report, 241-SY-101 Flexible Receiver System, Phase 1 testing

International Nuclear Information System (INIS)

Ritter, G.A.

1995-01-01

This document summarizes the results of the Phase 1 acceptance test of the 241-SY-101 Flexible Receiver System (FRS). This acceptance test consisted of a pressure-decay/leak test of the containment bag to verify that the seams along the length of the bag had been adequately sealed. The sealing integrity of the FRS must be verified to ensure that the release of waste and aerosols will be minimized during the removal of the test mixer pump from Tank 241-SY-101. The FRS is one of six major components of the Equipment Removal System, which has been designed to retrieve, transport, and store the mixer pump. This acceptance test was performed at Lancs Industries in Kirkland, Washington on January 17, 1995. The bag temperature-compensated pressure loss of 575 Pa was below the acceptance criteria of 625 Pa and the test results were therefore found to be acceptable. The bag manufacturer estimates that 80--90% of the pressure loss is attributed to leakage around the bag inflation valve where the pressure gage was connected. A leak detector was applied over the entire bag during the pre-tests and no leakage was found. Furthermore, the leak rate corresponding to this pressure loss is very small when compared to the acceptable leak rate of the completely assembled FRS. The sealing integrity of the assembled FRS is verified in Phase 3 testing

Effect of graphene oxide on undifferentiated and retinoic acid-differentiated SH-SY5Y cells line

Science.gov (United States)

Lv, Min; Zhang, Yujie; Liang, Le; Wei, Min; Hu, Wenbing; Li, Xiaoming; Huang, Qing

2012-06-01

Graphene oxide (GO), has created an unprecedented opportunity for development and application in biology, due to its abundant functional groups and well water solubility. Recently, the potential toxicity of GO in the environment and in humans has garnered more and more attention. In this paper, we systematically studied the cytotoxicity of GO nanosheets via examining the effect of GO on the morphology, viability and differentiation of a human neuroblastoma SH-SY5Y cell line, which was an ideal model used to study neuronal disease in vitro. The results suggested that GO had no obvious cytotoxicity at low concentration (cells exhibited dose- and time-dependent decreases at high concentration (>=80 μg mL-1). Moreover, GO did not induce apoptosis. Very interestingly, GO significantly enhanced the differentiation of SH-SY5Y induced-retinoic acid (RA) by evaluating neurite length and the expression of neuronal marker MAP2. These data provide a promising application for neurodegenerative diseases.

Protective effect of Pycnogenol in human neuroblastoma SH-SY5Y cells following acrolein-induced cytotoxicity.

Science.gov (United States)

Ansari, Mubeen A; Keller, Jeffrey N; Scheff, Stephen W

2008-12-01

Oxidative stress is one of the hypotheses involved in the etiology of Alzheimer's disease (AD). Considerable attention has been focused on increasing the intracellular glutathione (GSH) levels in many neurodegenerative diseases, including AD. Pycnogenol (PYC) has antioxidant properties and stabilizes intracellular antioxidant defense systems including glutathione levels. The present study investigated the protective effects of PYC on acrolein-induced oxidative cell toxicity in cultured SH-SY5Y neuroblastoma cells. Decreased cell survival in SH-SY5Y cultures treated with acrolein correlated with oxidative stress, increased NADPH oxidase activity, free radical production, protein oxidation/nitration (protein carbonyl, 3-nitrotyrosine), and lipid peroxidation (4-hydroxy-2-nonenal). Pretreatment with PYC significantly attenuated acrolein-induced cytotoxicity, protein damage, lipid peroxidation, and cell death. A dose-response study suggested that PYC showed protective effects against acrolein toxicity by modulating oxidative stress and increasing GSH. These findings provide support that PYC may provide a promising approach for the treatment of oxidative stress-related neurodegenerative diseases such as AD.

Strategic Sustainable Electric Power Energy for Ethiopia:- Electric ...

African Journals Online (AJOL)

Mengesha

Present trend in electrical engineering education; ... (EERS) USA plans to reduce its electric energy ... at the distribution center, step-down to low voltage. (400 V .... Ethiopian market and in use [13]. .... involved in the teaching EEPCo students.

Power Requirements Determined for High-Power-Density Electric Motors for Electric Aircraft Propulsion

Science.gov (United States)

Johnson, Dexter; Brown, Gerald V.

2005-01-01

Future advanced aircraft fueled by hydrogen are being developed to use electric drive systems instead of gas turbine engines for propulsion. Current conventional electric motor power densities cannot match those of today s gas turbine aircraft engines. However, if significant technological advances could be made in high-power-density motor development, the benefits of an electric propulsion system, such as the reduction of harmful emissions, could be realized.

Enhanced growth of neural networks on conductive cellulose-derived nanofibrous scaffolds

International Nuclear Information System (INIS)

Kuzmenko, Volodymyr; Kalogeropoulos, Theodoros; Thunberg, Johannes; Johannesson, Sara; Hägg, Daniel; Enoksson, Peter; Gatenholm, Paul

2016-01-01

The problem of recovery from neurodegeneration needs new effective solutions. Tissue engineering is viewed as a prospective approach for solving this problem since it can help to develop healthy neural tissue using supportive scaffolds. This study presents effective and sustainable tissue engineering methods for creating biomaterials from cellulose that can be used either as scaffolds for the growth of neural tissue in vitro or as drug screening models. To reach this goal, nanofibrous electrospun cellulose mats were made conductive via two different procedures: carbonization and addition of multi-walled carbon nanotubes. The resulting scaffolds were much more conductive than untreated cellulose material and were used to support growth and differentiation of SH-SY5Y neuroblastoma cells. The cells were evaluated by scanning electron microscopy and confocal microscopy methods over a period of 15 days at different time points. The results showed that the cellulose-derived conductive scaffolds can provide support for good cell attachment, growth and differentiation. The formation of a neural network occurred within 10 days of differentiation, which is a promising length of time for SH-SY5Y neuroblastoma cells. - Highlights: • The conductive scaffolds for neural tissue engineering are derived from cellulose. • The scaffolds are used to support growth and differentiation of SH-SY5Y cells. • Distinctive cell differentiation occurs within 10 days on conductive scaffolds. • Electrical conductivity and nanotopography improve neural network formation.

COOPERATIVE MODE OF ELECTRIC MOTOR AND INTERNAL COMBUSTION ENGINE OPERATION IN THE CONVERSION HYBRID CAR

Directory of Open Access Journals (Sweden)

V. Dvadnenko

2016-12-01

Full Text Available In the given article the authors proposed a method to control the car, which is converted into a hybrid one. The electric motor and combustion engine operate alternately in the car. They proposed a device for implementing this method and a circuit design for the device in question. They also calculated the dynamics of the vehicle under the joint acceleration.

Assessment of the potential for ammonium nitrate formation and reaction in Tank 241-SY-101

International Nuclear Information System (INIS)

Pederson, L.R.; Bryan, S.A.

1994-08-01

Two principal scenarios by which ammonium nitrate may be formed were considered: (a) precipitation of ammonium nitrate in the waste, and (b) ammonium nitrate formation via the gas phase reaction of ammonia and nitrogen dioxide. The first of these can be dismissed because ammonium ions, which are necessary for ammonium nitrate precipitation, can exist only in negligibly small concentrations in strongly alkaline solutions. Gas phase reactions between ammonia, nitrogen dioxide, and water vapor in the gas phase represent the most likely means by which ammonium nitrate aerosols could be formed in Tank 241-SY-101. Predicted ammonium nitrate formation rates are largely controlled by the concentration of nitrogen dioxide. This gas has not been detected among those gases vented from the wastes using Fourier Transform Infrared Spectrometry (FTIR) or mass spectrometry. While detection limits for nitrogen dioxide have not been established experimentally, the maximum concentration of nitrogen dioxide in the gas phase in Tank 241-SY-101 was estimated at 0.1 ppm based on calculations using the HITRAN data base and on FTIR spectra of gases vented from the wastes. At 50 C and with 100 ppm ammonia also present, less than one gram of ammonium nitrate per year is estimated to be formed in the tank. To date, ammonium nitrate has not been detected on HEPA filters in the ventilation system, so any quantity that has been formed in the tank must be quite small, in good agreement with rate calculations. The potential for runaway exothermic reactions involving ammonium nitrate in Tank 241-SY-101 is minimal. Dilution by non-reacting waste components, particularly water, would prevent hazardous exothermic reactions from occurring within the waste slurry, even if ammonium nitrate were present. 41 refs

System Design Description for the SY-101 Hydrogen Mitigation Test Project Data Acquisition and Control System (DACS-1)

Energy Technology Data Exchange (ETDEWEB)

ERMI, A.M.

2000-01-24

This document describes the hardware and software of the computer subsystems for the Data Acquisition and Control System (DACS) used in mitigation tests conducted on waste tank 241-SY-101 at the Hanford Nuclear Reservation.

Characterization of hybrid lighting systems of the Electrical Engineering Building in the Industrial University of Santander

Science.gov (United States)

Galvis, D.; Exposito, C.; Osma, G.; Amado, L.; Ordóñez, G.

2016-07-01

This paper presents an analysis of hybrid lighting systems of Electrical Engineering Building in the Industrial University of Santander, which is a pilot of green building for warm- tropical conditions. Analysis of lighting performance of inner spaces is based on lighting curves obtained from characterization of daylighting systems of these spaces. A computation tool was made in Excel-Visual Basic to simulate the behaviour of artificial lighting system considering artificial control system, user behaviour and solar condition. Also, this tool allows to estimate the electrical energy consumption of the lighting system for a day, a month and a year.

Current Status and Issues of Nuclear Engineering Research and Educational Facilities in Universities

International Nuclear Information System (INIS)

2004-01-01

It is important to discuss about nuclear engineering research and educational facilities in universities after new educational foundation. 12 universities investigated issues and a countermeasure of them. The results of a questionnaire survey, issues and countermeasure are shown in this paper. The questionnaire on the future nuclear researches, development of education, project, maintenance of nuclear and radioactive facilities and accelerator, control of uranium in subcritical test facilities, use of new corporation facilities, the fixed number of student, number of graduate, student experiments, themes of experiments and researches, the state of educational facilities are carried out. The results of questionnaire were summarized as followings: the fixed number of student (B/M/D) on nuclear engineering, exercise of reactor, education, themes, educational and research facilities, significance of nuclear engineering education in university and proposal. (S.Y.)

Stable Operation and Electricity Generating Characteristics of a Single-Cylinder Free Piston Engine Linear Generator: Simulation and Experiments

Directory of Open Access Journals (Sweden)

Huihua Feng

2015-01-01

Full Text Available We present a novel design of a single-cylinder free piston engine linear generator (FPELG incorporating a linear motor as a rebound device. A systematic simulation model of this FPELG system was built containing a kinematic and dynamic model of the piston and mover, a magneto-electric model of the linear generator, a thermodynamic model of the single-cylinder engine, and a friction model between the piston ring and cylinder liner. Simulations were performed to understand the relationships between pre-set motor parameters and the running performance of the FPELG. From the simulation results, it was found that a motor rebound force with a parabolic profile had clear advantages over a force with a triangular profile, such as a higher running frequency and peak cylinder pressure, faster piston motion, etc. The rebound position and the amplitude of rebound force were also determined by simulations. The energy conversion characteristics of the generator were obtained from our FPELG test rig. The parameters of intake pressure, motor frequency, and load resistance were varied over certain ranges, and relationships among these three parameters were obtained. The electricity-generating characteristic parameters include output power and system efficiency, which can measure the quality of matching the controllable parameters. The output power can reach 25.9 W and the system efficiency can reach 13.7%. The results in terms of matching parameters and electricity-generating characteristics should be useful to future research in adapting these engines to various operating modes.

Newnes electrical pocket book

CERN Document Server

Reeves, E A

2013-01-01

Newnes Electrical Pocket Book, Twenty-first Edition, provides engineers with convenient access to various facts, tables, and formulae relating to the particular branch of engineering being dealt with. In the case of electrical engineering, it is essential that the engineer have a clear understanding of the methods by which the various formulae are derived to ensure that any particular formulae is applicable to the conditions being considered. The first section of the Pocket Book is devoted to the theoretical groundwork upon which all the practical applications are based. This covers symbols,

Electric distribution systems

CERN Document Server

Sallam, A A

2010-01-01

"Electricity distribution is the penultimate stage in the delivery of electricity to end users. The only book that deals with the key topics of interest to distribution system engineers, Electric Distribution Systems presents a comprehensive treatment of the subject with an emphasis on both the practical and academic points of view. Reviewing traditional and cutting-edge topics, the text is useful to practicing engineers working with utility companies and industry, undergraduate graduate and students, and faculty members who wish to increase their skills in distribution system automation and monitoring."--

Lack of Prenylated Proteins, Autophagy Impairment and Apoptosis in SH-SY5Y Neuronal Cell Model of Mevalonate Kinase Deficiency

Directory of Open Access Journals (Sweden)

Paola Maura Tricarico

2017-03-01

Full Text Available Background/Aims: Mevalonate Kinase Deficiency (MKD, is a hereditary disease due to mutations in mevalonate kinase gene (MVK. MKD has heterogeneous clinical phenotypes: the correlation between MVK mutations and MKD clinical phenotype is still to be fully elucidated. Deficiency of prenylated proteins has been hypothesized as possible MKD pathogenic mechanism. Based on this hypothesis and considering that neurologic impairment characterizes Mevalonic Aciduria (MA, the most severe form of MKD, we studied the effects of I268T and N301T MVK mutations on protein prenylation, autophagy and programmed cell death in SH-SY5Y neuroblastoma cell lines. Methods: SH-SY5Y cells were transiently transfected, with the pCMV-6 plasmid containing MVK wild type and the two mutated sequences. Protein prenylation levels were evaluated using GFP-RhoA-F to assess farnesylation, and GFP-RhoA to evaluate geranylgeranylation; autophagy was measured by evaluating LC3 and p62 protein levels, while Annexin V-FITC and Propidium Iodide staining allowed apoptosis detection. Results: MVK mutants’ over-expression causes decreased levels of farnesylation and geranylgeranylation, and also increased LC3 lipidation in SH-SY5Y, with concomitant p62 accumulation. Treatment with bafilomycin A1 (an inhibitor of vacuolar H+-ATPase, a late autophagy inhibitor further increase LC3-II and p62 levels, suggesting that degradation of autophagolysosome could be impaired. SH-SY5Y, with both MVK mutants, showed apoptosis increase; the presence of N301T associated with augmented cell death. Conclusions: We hypothesize that mevalonate pathway impairment causes alteration of farnesylation and geranylgeranylation proteins and alteration of the autophagic flux; these changes can induce apoptosis, possibly more relevant in the presence of N301T mutation.

Lack of Prenylated Proteins, Autophagy Impairment and Apoptosis in SH-SY5Y Neuronal Cell Model of Mevalonate Kinase Deficiency.

Science.gov (United States)

Tricarico, Paola Maura; Romeo, Alessandra; Gratton, Rossella; Crovella, Sergio; Celsi, Fulvio

2017-01-01

Mevalonate Kinase Deficiency (MKD), is a hereditary disease due to mutations in mevalonate kinase gene (MVK). MKD has heterogeneous clinical phenotypes: the correlation between MVK mutations and MKD clinical phenotype is still to be fully elucidated. Deficiency of prenylated proteins has been hypothesized as possible MKD pathogenic mechanism. Based on this hypothesis and considering that neurologic impairment characterizes Mevalonic Aciduria (MA), the most severe form of MKD, we studied the effects of I268T and N301T MVK mutations on protein prenylation, autophagy and programmed cell death in SH-SY5Y neuroblastoma cell lines. SH-SY5Y cells were transiently transfected, with the pCMV-6 plasmid containing MVK wild type and the two mutated sequences. Protein prenylation levels were evaluated using GFP-RhoA-F to assess farnesylation, and GFP-RhoA to evaluate geranylgeranylation; autophagy was measured by evaluating LC3 and p62 protein levels, while Annexin V-FITC and Propidium Iodide staining allowed apoptosis detection. MVK mutants' over-expression causes decreased levels of farnesylation and geranylgeranylation, and also increased LC3 lipidation in SH-SY5Y, with concomitant p62 accumulation. Treatment with bafilomycin A1 (an inhibitor of vacuolar H+-ATPase, a late autophagy inhibitor) further increase LC3-II and p62 levels, suggesting that degradation of autophagolysosome could be impaired. SH-SY5Y, with both MVK mutants, showed apoptosis increase; the presence of N301T associated with augmented cell death. We hypothesize that mevalonate pathway impairment causes alteration of farnesylation and geranylgeranylation proteins and alteration of the autophagic flux; these changes can induce apoptosis, possibly more relevant in the presence of N301T mutation. © 2017 The Author(s)Published by S. Karger AG, Basel.

Neuroprotective effects of Salvia aristata Aucher ex Benth. on hydrogen peroxide induced apoptosis in SH-SY5Y neuroblastoma cells

Directory of Open Access Journals (Sweden)

M. A. Esmaeili

2015-08-01

Full Text Available Background and objectives: Oxidative stress is implicated in the neuronal damage associated with Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, amyotropic lateral sclerosis and cerebral ischemic stroke. The present work was designed to establish the neuroprotective effects of Salvia aristata extract on H2O2-induced apoptosis in human dopaminergic SH-SY5Y cells. Methods: The total phenol and flavonoids contents of the plant extracts were quantified by colorimetric methods. The antioxidant activity was assessed using DPPH free radicals scavenging activity assay, and the neuroprotective effect on H2O2-induced oxidative stress was also investigated using human dopaminergic SH-SY5Y cells by MTT assay and western blotting techniques. Results: The highest scavenging activity was found for methanol extract of S. aristata roots (85.28 ± 2.61 μg/mL, with the highest total phenolic and flavonoids content (90.28 mg total phenols as gallic acid and 250.12 mg total flavonoids as rutin, respectively. Our results also, showed that H2O2-induced cytotoxicity in SH-SY5Y cells was suppressed by treatment with S. aristata. Moreover, S. aristata root extract was effective in attenuating the disruption of mitochondrial membrane potential and apoptotic cell death has induced by H2O2.  S. aristata suppressed the down-regulation of Bcl-2, upregulation of Bax, and the release of mitochondrial cytochrome c to cytosol. In addition, S. aristata attenuated caspase-3, and -9 activation, and eventually protected the cells against H2O2-induced apoptosis. Conclusion: Theresults of the present study suggest that treatment of SH-SY5Y cells with S. aristata could block H2O2-induced apoptosis by regulating Bcl-2 family members and by suppressing caspase cascade activation.

Sodium sulfur electric vehicle battery engineering program final report, September 2, 1986--June 15, 1993

Energy Technology Data Exchange (ETDEWEB)

NONE

1993-06-01

In September 1986 a contract was signed between Chloride Silent Power Limited (CSPL) and Sandia National Laboratories (SNL) entitled ``Sodium Sulfur Electric Vehicle Battery Engineering Program``. The aim of the cost shared program was to advance the state of the art of sodium sulfur batteries for electric vehicle propulsion. Initially, the work statement was non-specific in regard to the vehicle to be used as the design and test platform. Under a separate contract with the DOE, Ford Motor Company was designing an advanced electric vehicle drive system. This program, called the ETX II, used a modified Aerostar van for its platform. In 1987, the ETX II vehicle was adopted for the purposes of this contract. This report details the development and testing of a series of battery designs and concepts which led to the testing, in the US, of three substantial battery deliverables.

Békésy's contributions to our present understanding of sound conduction to the inner ear.

Science.gov (United States)

Puria, Sunil; Rosowski, John J

2012-11-01

In our daily lives we hear airborne sounds that travel primarily through the external and middle ear to the cochlear sensory epithelium. We also hear sounds that travel to the cochlea via a second sound-conduction route, bone conduction. This second pathway is excited by vibrations of the head and body that result from substrate vibrations, direct application of vibrational stimuli to the head or body, or vibrations induced by airborne sound. The sensation of bone-conducted sound is affected by the presence of the external and middle ear, but is not completely dependent upon their function. Measurements of the differential sensitivity of patients to airborne sound and direct vibration of the head are part of the routine battery of clinical tests used to separate conductive and sensorineural hearing losses. Georg von Békésy designed a careful set of experiments and pioneered many measurement techniques on human cadaver temporal bones, in physical models, and in human subjects to elucidate the basic mechanisms of air- and bone-conducted sound. Looking back one marvels at the sheer number of experiments he performed on sound conduction, mostly by himself without the aid of students or research associates. Békésy's work had a profound impact on the field of middle-ear mechanics and bone conduction fifty years ago when he received his Nobel Prize. Today many of Békésy's ideas continue to be investigated and extended, some have been supported by new evidence, some have been refuted, while others remain to be tested. Copyright © 2012 Elsevier B.V. All rights reserved.

The Systemic Sclerosis Questionnaire (SySQ): Validation of the translation of the original German version into Spanish and its relationship to the disease and to quality of life.

Science.gov (United States)

Cruz-Domínguez, Maria Pilar; Casarrubias-Ramírez, Moisés; Gasca-Martínez, Victor; Maldonado García, Cindy; Carranza-Muleiro, Rosa Angélica; Medina, Gabriela; García-Collinot, Grettel; Montes-Cortes, Daniel Hector

2017-12-11

Translation, transculturation and validity of the self-administered questionnaire for functionality (Systemic Sclerosis Questionnaires [SySQ]) for use in Spanish patients with systemic sclerosis and its relationship to the severity of the disease and to quality of life. We conducted an observational analytical study to perform a cross-cultural validation of the self-administered questionnaire on functionality in scleroderma. The validity of the form and content was evaluated by an expert panel. The method included: a) adaptation into Spanish of the construct for translation and back translation, and transculturation; b) internal consistency with the SySQ (Cronbach's alpha), and c) reproducibility was assessed taking into account all occasions in which the test was performed with Cohen's kappa. Additionally, we calculated the Spearman correlation coefficient with the Medsger severity scale, Health Assessment Questionnaire score and SF-36 score. We included 70 patients with systemic sclerosis: age 17-78 (51±12) years, 65 (93%) were women, diffuse/limited subtype 64/36%, disease duration of 0.5-40 years. Optimal internal consistency for all categories of the final version of SySQ (Cronbach's α of 0.961) and intraobserver reliability in 2 tests over a 2-week interval (Cohen's kappa coefficient 0.618) and optimal interobserver reliability in 2 tests on the same day (Cohen's kappa coefficient 0.911). Moderate correlation between functionality by SySQ and by Health Assessment Questionnaire (r=0.573, P<.0001). Inverse correlation between SySQ and quality of life mental health domain SF-36 (r=-0.435, P<.001) and physical domain SF-36 (r=-0.638, P<.001). Medsger severity scale (tendon, heart, lung, vascular) also showed significant correlation with SySQ. SySQ in this validated Spanish version is a suitable instrument to measure functional status in patients with systemic sclerosis. Reduced functionality is related to greater tendon and peripheral vascular involvement and

The Neuroprotective Effects of Brazilian Green Propolis on Neurodegenerative Damage in Human Neuronal SH-SY5Y Cells

Directory of Open Access Journals (Sweden)

Junjun Ni

2017-01-01

Full Text Available Oxidative stress and synapse dysfunction are the major neurodegenerative damage correlated to cognitive impairment in Alzheimer’s disease (AD. We have found that Brazilian green propolis (propolis improves the cognitive functions of mild cognitive impairment patients living at high altitude; however, mechanism underlying the effects of propolis is unknown. In the present study, we investigated the effects of propolis on oxidative stress, expression of brain-derived neurotrophic factor (BDNF, and activity-regulated cytoskeleton-associated protein (Arc, the critical factors of synapse efficacy, using human neuroblastoma SH-SY5Y cells. Pretreatment with propolis significantly ameliorated the hydrogen peroxide- (H2O2- induced cytotoxicity in SH-SY5Y cells. Furthermore, propolis significantly reduced the H2O2-generated reactive oxygen species (ROS derived from mitochondria and 8-oxo-2′-deoxyguanosine (8-oxo-dG, the DNA oxidative damage marker but significantly reversed the fibrillar β-amyloid and IL-1β-impaired BDNF-induced Arc expression in SH-SY5Y cells. Furthermore, propolis significantly upregulated BDNF mRNA expression in time- and dose-dependent manners. In addition, propolis induced Arc mRNA and protein expression via phosphoinositide-3 kinase (PI3K. These observations strongly suggest that propolis protects from the neurodegenerative damage in neurons through the properties of various antioxidants. The present study provides a potential molecular mechanism of Brazilian green propolis in prevention of cognitive impairment in AD as well as aging.

Integrated powertrain control for hybrid electric vehicles with electric variable transmission

NARCIS (Netherlands)

Kessels, J.T.B.A.; Foster, D.L.; Bosch, van den P.P.J.

2009-01-01

The electric variable transmission (EVT) offers a powersplit for hybrid electric vehicles by integrating two motor/ generator sets into one electric machine. This double rotor concept implements a continuously variable transmission between the engine and the driveline, including the possibility for

Latest Progress of Fault Detection and Localization in Complex Electrical Engineering

Science.gov (United States)

Zhao, Zheng; Wang, Can; Zhang, Yagang; Sun, Yi

2014-01-01

In the researches of complex electrical engineering, efficient fault detection and localization schemes are essential to quickly detect and locate faults so that appropriate and timely corrective mitigating and maintenance actions can be taken. In this paper, under the current measurement precision of PMU, we will put forward a new type of fault detection and localization technology based on fault factor feature extraction. Lots of simulating experiments indicate that, although there are disturbances of white Gaussian stochastic noise, based on fault factor feature extraction principal, the fault detection and localization results are still accurate and reliable, which also identifies that the fault detection and localization technology has strong anti-interference ability and great redundancy.

Performance and driveline analyses of engine capacity in range extender engine hybrid vehicle

Science.gov (United States)

Praptijanto, Achmad; Santoso, Widodo Budi; Nur, Arifin; Wahono, Bambang; Putrasari, Yanuandri

2017-01-01

In this study, range extender engine designed should be able to meet the power needs of a power generator of hybrid electrical vehicle that has a minimum of 18 kW. Using this baseline model, the following range extenders will be compared between conventional SI piston engine (Baseline, BsL), engine capacity 1998 cm3, and efficiency-oriented SI piston with engine capacity 999 cm3 and 499 cm3 with 86 mm bore and stroke square gasoline engine in the performance, emission prediction of range extender engine, standard of charge by using engine and vehicle simulation software tools. In AVL Boost simulation software, range extender engine simulated from 1000 to 6000 rpm engine loads. The highest peak engine power brake reached up to 38 kW at 4500 rpm. On the other hand the highest torque achieved in 100 Nm at 3500 rpm. After that using AVL cruise simulation software, the model of range extended electric vehicle in series configuration with main components such as internal combustion engine, generator, electric motor, battery and the arthemis model rural road cycle was used to simulate the vehicle model. The simulation results show that engine with engine capacity 999 cm3 reported the economical performances of the engine and the emission and the control of engine cycle parameters.

A contribution to the practical realization of aging management of electrical and control engineering according KTA 1403

International Nuclear Information System (INIS)

Disco, S.; Kaflowski, G.; Waber, P.

2011-01-01

The contribution is an exemplary demonstration of the practical aging management according KTA 1403. Aging management is aimed to insure sufficient availability of safety systems to control all design-based accidents and to avoid a significant increase of systematic failures. The special features of electrical and control engineering are identified. The implementation of aging management is actually stepwise realized as pilot project in the NPP Grafenrheinfeld (KKG). The pilot project is supposed to optimize the procedures. A deterministic quantitative evaluation of only restricted to few components of the electrical and control systems. For most components of the electrical and control systems a probabilistic experience-based evaluation without identification or quantification of materials damage mechanisms is performed using the AREVA software tool COMSY-ELT.

DOES ELECTRIC CAR PRODUCE EMISSIONS?

Directory of Open Access Journals (Sweden)

Vladimír RIEVAJ

2017-03-01

Full Text Available This article focuses on the comparison of the amount of emissions produced by vehicles with a combustion engine and electric cars. The comparison, which is based on the LCA factor results, indicates that an electric car produces more emissions than a vehicle with combustion engine. The implementation of electric cars will lead to an increase in the production of greenhouse gases.

Presenilin-1 mutations alter K+ currents in the human neuroblastoma cell line, SH-SY5Y

DEFF Research Database (Denmark)

Plant, Leigh D; Boyle, John P; Thomas, Natasha M

2002-01-01

Mutations in presenilin 1 (PS1) are the major cause of autosomal dominant Alzheimer's disease. We have measured the voltage-gated K+ current in the human neuroblastoma cell line SH-SY5Y using whole-cell patch-clamp. When cells were stably transfected to over-express PS1, no change in K+ current...

Electricity

CERN Document Server

Basford, Leslie

2013-01-01

Electricity Made Simple covers the fundamental principles underlying every aspect of electricity. The book discusses current; resistance including its measurement, Kirchhoff's laws, and resistors; electroheat, electromagnetics and electrochemistry; and the motor and generator effects of electromagnetic forces. The text also describes alternating current, circuits and inductors, alternating current circuits, and a.c. generators and motors. Other methods of generating electromagnetic forces are also considered. The book is useful for electrical engineering students.

Free-Piston Stirling Engines

Science.gov (United States)

Shaltens, Richard K.

1989-01-01

Engines promise cost-effective solar-power generation. Report describes two concepts for Stirling-engine systems for conversion of solar heat to electrical energy. Recognized most promising technologies for meeting U.S. Department of Energy goals for performance and cost for terrestrial electrical-energy sources.

Thermocouple module halt failure acceptance test procedure for Tank 241-SY-101 DACS-1

International Nuclear Information System (INIS)

Ermi, A.M.

1997-01-01

The readiness of the Tank 241-SY-101 Data Acquisition and Control System (DACS-1) to provide monitoring and alarms for a halt failure of any thermocouple module will be tested during the performance of this procedure. Updated DACS-1 ''1/0 MODULE HEALTH STATUS'', ''MININ1'', and ''MININ2'' screens, which now provide indication of thermocouple module failure, will also be tested as part of this procedure

Self-Regulated Learning Strategies of Engineering College Students While Learning Electric Circuit Concepts with Enhanced Guided Notes

Science.gov (United States)

Lawanto, Oenardi; Santoso, Harry

2013-01-01

The current study evaluated engineering college students' self-regulated learning (SRL) strategies while learning electric circuit concepts using enhanced guided notes (EGN). Our goal was to describe how students exercise SRL strategies and how their grade performance changes after using EGN. Two research questions guided the study: (1) To what…

Interdisciplinary Team-Teaching Experience for a Computer and Nuclear Energy Course for Electrical and Computer Engineering Students

Science.gov (United States)

Kim, Charles; Jackson, Deborah; Keiller, Peter

2016-01-01

A new, interdisciplinary, team-taught course has been designed to educate students in Electrical and Computer Engineering (ECE) so that they can respond to global and urgent issues concerning computer control systems in nuclear power plants. This paper discusses our experience and assessment of the interdisciplinary computer and nuclear energy…

Study on vibration behaviors of engineered barrier system

Energy Technology Data Exchange (ETDEWEB)

Mikoshiba, Tadashi; Ogawa, Nobuyuki; Minowa, Chikahiro [National Research Inst. for Earth Science and Disaster Prevention, Tsukuba, Ibaraki (Japan)

1999-02-01

Small engineered barrier model was mode and tested by vibrating with the random wave and the real earthquake wave. The wave observed at Kamaishi (N-S, N-W), Iwate Prefecture, in September 6, 1993, and Kobe (N-S) etc. were used as the real earthquake waves. The trial overpack showed non-linear characteristics (soft spring) by vibrating with the random wave. The pressure and acceleration of trial overpack and constraint container increased with increasing the vibration level of the real earthquake wave. The trial overpack moved the maximum 1.7 mm of displacement and 16 mm subsidence. The results showed both waves rocked the trialpack. (S.Y.)

Ten essential skills for electrical engineers

CERN Document Server

Dorr, Barry

2014-01-01

Engineers know that, as in any other discipline, getting a good job requires practical, up-to-date skills. An engineering degree provides a broad set of fundamentals. Ten Essential Skills applies those fundamentals to practical tasks required by employers. Written in a user-friendly, no-nonsense format, the book reviews practical skills using the latest tools and techniques, and features a companion website with interview practice problems and advanced material for readers wishing to pursue additional skills. With this book, aspiring and current engineers may approach job interviews confident

A comparison of genotyping-by-sequencing analysis methods on low-coverage crop datasets shows advantages of a new workflow, GB-eaSy.

Science.gov (United States)

Wickland, Daniel P; Battu, Gopal; Hudson, Karen A; Diers, Brian W; Hudson, Matthew E

2017-12-28

Genotyping-by-sequencing (GBS), a method to identify genetic variants and quickly genotype samples, reduces genome complexity by using restriction enzymes to divide the genome into fragments whose ends are sequenced on short-read sequencing platforms. While cost-effective, this method produces extensive missing data and requires complex bioinformatics analysis. GBS is most commonly used on crop plant genomes, and because crop plants have highly variable ploidy and repeat content, the performance of GBS analysis software can vary by target organism. Here we focus our analysis on soybean, a polyploid crop with a highly duplicated genome, relatively little public GBS data and few dedicated tools. We compared the performance of five GBS pipelines using low-coverage Illumina sequence data from three soybean populations. To address issues identified with existing methods, we developed GB-eaSy, a GBS bioinformatics workflow that incorporates widely used genomics tools, parallelization and automation to increase the accuracy and accessibility of GBS data analysis. Compared to other GBS pipelines, GB-eaSy rapidly and accurately identified the greatest number of SNPs, with SNP calls closely concordant with whole-genome sequencing of selected lines. Across all five GBS analysis platforms, SNP calls showed unexpectedly low convergence but generally high accuracy, indicating that the workflows arrived at largely complementary sets of valid SNP calls on the low-coverage data analyzed. We show that GB-eaSy is approximately as good as, or better than, other leading software solutions in the accuracy, yield and missing data fraction of variant calling, as tested on low-coverage genomic data from soybean. It also performs well relative to other solutions in terms of the run time and disk space required. In addition, GB-eaSy is built from existing open-source, modular software packages that are regularly updated and commonly used, making it straightforward to install and maintain

The Integration of Gasification Systems with Gas Engine by Developing Wet Tar Scrubbers and Gas Filter to Produce Electrical Energy from Biomass

Directory of Open Access Journals (Sweden)

Siregar Kiman

2018-01-01

Full Text Available The need for energy especially biomass-based renewable energy continues to increase in Indonesia. The objective of this research was to design downdraft gasifier machine with high content of combustible gas on gas engine. Downdraft gasifier machine was adjusted with the synthetic gas produced from biomass. Besides that, the net energy ratio, net energy balance, renewable index, economic analysis and impact assessment also been conducted. Gas engine that was designed in this research had been installed with capacity of 25 kW with diameter and height of reactorwere 900 mm and 1 000 mm respectively. The method used here werethe design the Detailed Engineering Design, assembly, and performance test of gas engine. The result showed that gas engine for biomass can be operated for 8 h with performance engine of 84 % and capacity of 25 kW. Net energy balance, net energy ratio, and renewable index was 30 MJ/kW h electric; 0.89; 0.76 respectively. The value of GHG emission of Biomass Power Generation is 0.03 kg-CO2 eq per MJ. Electrical production cost for Biomass Power Generation is about IDR 1 500 per kW h which is cheaper than solar power generation which is about of IDR 3 300 per kW h.

Electrical circuit theory and technology

CERN Document Server

Bird, John

2014-01-01

This much-loved textbook explains the principles of electrical circuit theory and technology so that students of electrical and mechanical engineering can master the subject. Real-world situations and engineering examples put the theory into context. The inclusion of worked problems with solutions help you to learn and further problems then allow you to test and confirm you have fully understood each subject. In total the book contains 800 worked problems, 1000 further problems and 14 revision tests with answers online. This an ideal text for foundation and undergraduate degree students and those on upper level vocational engineering courses, in particular electrical and mechanical. It provides a sound understanding of the knowledge required by technicians in fields such as electrical engineering, electronics and telecommunications. This edition has been updated with developments in key areas such as semiconductors, transistors, and fuel cells, along with brand new material on ABCD parameters and Fourier's An...

Electric machine for hybrid motor vehicle

Science.gov (United States)

Hsu, John Sheungchun

2007-09-18

A power system for a motor vehicle having an internal combustion engine and an electric machine is disclosed. The electric machine has a stator, a permanent magnet rotor, an uncluttered rotor spaced from the permanent magnet rotor, and at least one secondary core assembly. The power system also has a gearing arrangement for coupling the internal combustion engine to wheels on the vehicle thereby providing a means for the electric machine to both power assist and brake in relation to the output of the internal combustion engine.

Blow molding electric drives of Mechanical Engineering

Science.gov (United States)

Bukhanov, S. S.; Ramazanov, M. A.; Tsirkunenko, A. T.

2018-03-01

The article considers the questions about the analysis of new possibilities, which gives the use of adjustable electric drives for blowing mechanisms of plastic production. Thus, the use of new semiconductor converters makes it possible not only to compensate the instability of the supply network by using special dynamic voltage regulators, but to improve (correct) the power factor. The calculation of economic efficiency in controlled electric drives of blowing mechanisms is given. On the basis of statistical analysis, the calculation of the reliability parameters of the regulated electric drives’ elements under consideration is given. It is shown that an increase in the reliability of adjustable electric drives is possible both due to overestimation of the electric drive’s installed power, and in simpler schemes with pulse-vector control.

Electrically conductive gold nanoparticle-chitosan thermosensitive hydrogels for cardiac tissue engineering

Energy Technology Data Exchange (ETDEWEB)

Baei, Payam [Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran (Iran, Islamic Republic of); Cardiovascular Engineering Laboratory, Faculty of Biomedical Engineering, Amirkabir University of Technology (Tehran Polytechnic), Tehran (Iran, Islamic Republic of); Jalili-Firoozinezhad, Sasan [Department of Biomedicine and Surgery, University Hospital Basel, University of Basel, Hebelstrasse 20, CH-4031 Basel (Switzerland); Department of Bioengineeringand IBB - Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa (Portugal); Rajabi-Zeleti, Sareh [Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran (Iran, Islamic Republic of); Tafazzoli-Shadpour, Mohammad [Cardiovascular Engineering Laboratory, Faculty of Biomedical Engineering, Amirkabir University of Technology (Tehran Polytechnic), Tehran (Iran, Islamic Republic of); Baharvand, Hossein, E-mail: Baharvand@royaninstitute.org [Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran (Iran, Islamic Republic of); Department of Developmental Biology, University of Science and Culture, ACECR, Tehran (Iran, Islamic Republic of); Aghdami, Nasser, E-mail: Nasser.Aghdami@royaninstitute.org [Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran (Iran, Islamic Republic of)

2016-06-01

Injectable hydrogels that resemble electromechanical properties of the myocardium are crucial for cardiac tissue engineering prospects. We have developed a facile approach that uses chitosan (CS) to generate a thermosensitive conductive hydrogel with a highly porous network of interconnected pores. Gold nanoparticles (GNPs) were evenly dispersed throughout the CS matrix in order to provide electrical cues. The gelation response and electrical conductivity of the hydrogel were controlled by different concentrations of GNPs. The CS-GNP hydrogels were seeded with mesenchymal stem cells (MSCs) and cultivated for up to 14 days in the absence of electrical stimulations. CS-GNP scaffolds supported viability, metabolism, migration and proliferation of MSCs along with the development of uniform cellular constructs. Immunohistochemistry for early and mature cardiac markers showed enhanced cardiomyogenic differentiation of MSCs within the CS-GNP compared to the CS matrix alone. The results of this study demonstrate that incorporation of nanoscale electro-conductive GNPs into CS hydrogels enhances the properties of myocardial constructs. These constructs could find utilization for regeneration of other electroactive tissues. - Highlights: • Thermosensitive electro-conductive hydrogels were prepared from CS and GNPs. • Gelation time and conductivity were tuned by varying concentration of GNPs. • CS-2GNP with gelation time of 25.7 min and conductivity of 0.13 S·m{sup −1} was selected for in vitro studies. • CS-2GNP supported active metabolism, migration and proliferation of MSCs. • Expression of cardiac markers increased about two-fold in CS-2GNP compared to CS.

Electrically conductive gold nanoparticle-chitosan thermosensitive hydrogels for cardiac tissue engineering

International Nuclear Information System (INIS)

Baei, Payam; Jalili-Firoozinezhad, Sasan; Rajabi-Zeleti, Sareh; Tafazzoli-Shadpour, Mohammad; Baharvand, Hossein; Aghdami, Nasser

2016-01-01

Injectable hydrogels that resemble electromechanical properties of the myocardium are crucial for cardiac tissue engineering prospects. We have developed a facile approach that uses chitosan (CS) to generate a thermosensitive conductive hydrogel with a highly porous network of interconnected pores. Gold nanoparticles (GNPs) were evenly dispersed throughout the CS matrix in order to provide electrical cues. The gelation response and electrical conductivity of the hydrogel were controlled by different concentrations of GNPs. The CS-GNP hydrogels were seeded with mesenchymal stem cells (MSCs) and cultivated for up to 14 days in the absence of electrical stimulations. CS-GNP scaffolds supported viability, metabolism, migration and proliferation of MSCs along with the development of uniform cellular constructs. Immunohistochemistry for early and mature cardiac markers showed enhanced cardiomyogenic differentiation of MSCs within the CS-GNP compared to the CS matrix alone. The results of this study demonstrate that incorporation of nanoscale electro-conductive GNPs into CS hydrogels enhances the properties of myocardial constructs. These constructs could find utilization for regeneration of other electroactive tissues. - Highlights: • Thermosensitive electro-conductive hydrogels were prepared from CS and GNPs. • Gelation time and conductivity were tuned by varying concentration of GNPs. • CS-2GNP with gelation time of 25.7 min and conductivity of 0.13 S·m"−"1 was selected for in vitro studies. • CS-2GNP supported active metabolism, migration and proliferation of MSCs. • Expression of cardiac markers increased about two-fold in CS-2GNP compared to CS.

Engineering approach to model and compute electric power markets settlements

International Nuclear Information System (INIS)

Kumar, J.; Petrov, V.

2006-01-01

Back-office accounting settlement activities are an important part of market operations in Independent System Operator (ISO) organizations. A potential way to measure ISO market design correctness is to analyze how well market price signals create incentives or penalties for creating an efficient market to achieve market design goals. Market settlement rules are an important tool for implementing price signals which are fed back to participants via the settlement activities of the ISO. ISO's are currently faced with the challenge of high volumes of data resulting from the increasing size of markets and ever-changing market designs, as well as the growing complexity of wholesale energy settlement business rules. This paper analyzed the problem and presented a practical engineering solution using an approach based on mathematical formulation and modeling of large scale calculations. The paper also presented critical comments on various differences in settlement design approaches to electrical power market design, as well as further areas of development. The paper provided a brief introduction to the wholesale energy market settlement systems and discussed problem formulation. An actual settlement implementation framework and discussion of the results and conclusions were also presented. It was concluded that a proper engineering approach to this domain can yield satisfying results by formalizing wholesale energy settlements. Significant improvements were observed in the initial preparation phase, scoping and effort estimation, implementation and testing. 5 refs., 2 figs

Structural synthesis of electrical engineering complex’ control system of a plant for plastic shaping of the ceramic mixture

Directory of Open Access Journals (Sweden)

Galitskov Stanislav

2017-01-01

Full Text Available Production of ceramic bricks with the required strength imposes significant restrictions on the process control of plastic shaping of the ceramic mixture in the auger extruder. It is due to several factors. Firstly, the certain nonstationarity of rheological properties of the source raw materials necessitates the automatic task-oriented changes in combinations of such values as shear rate, ceramic mixture moisture and vacuum pressure in the vacuum chamber of the extruder. To solve this problem it is necessary to maintain a coordinated control of the relevant automatic control systems of the electrical engineering complex. The second problem is the lack of technical tools to measure the values of shear rate in the pressure head of the extruder. And finally, the third factor is a necessity for monitoring and modeling of operating steps in brick production – from shaping to finished product output, that is a necessity to assess the impact of drying and firing processes on the possibility to make bricks of specified strength. The paper considers structural synthesis of the electrical engineering complex’ control system for plastic shaping of the ceramic mixture, including the problem of coordinated control: of the vacuum pump’ electrical drive, of the solenoid valve for water dosing, of the belt feeder’ electrical drives, of the mixer and the auger, as well as the use of digital observers of technological controlled coordinates and models in further phases of brick production.

Effect of ellagic acid on proliferation, cell adhesion and apoptosis in SH-SY5Y human neuroblastoma cells.

Science.gov (United States)

Fjaeraa, Christina; Nånberg, Eewa

2009-05-01

Ellagic acid, a polyphenolic compound found in berries, fruits and nuts, has been shown to possess growth-inhibiting and apoptosis promoting activities in cancer cell lines in vitro. The objective of this study was to investigate the effect of ellagic acid in human neuroblastoma SH-SY5Y cells. In cultures of SH-SY5Y cells incubated with ellagic acid, time- and concentration-dependent inhibitory effects on cell number were demonstrated. Ellagic acid induced cell detachment, decreased cell viability and induced apoptosis as measured by DNA strand breaks. Ellagic acid-induced alterations in cell cycle were also observed. Simultaneous treatment with all-trans retinoic acid did not rescue the cells from ellagic acid effects. Furthermore, the results suggested that pre-treatment with all-trans retinoic acid to induce differentiation and cell cycle arrest did not rescue the cells from ellagic acid-induced cell death.

Materials science and engineering for electric power generation - success by cooperation

International Nuclear Information System (INIS)

Schmatjko, K.J.; Tenckhoff, E.

1994-01-01

Successful R and D cooperation relies on the coincidence of a general priority for the respective field of research and a strategic relevance of the results for the industrial partner. These two aspects are compared by a portfolio technique for R and D on advanced materials in electric power engineering. The approach is exemplified by tasks in research, development and processing of materials with improved high-temperature performance. Higher operation temperatures result in more efficient steam and gas turbines and fuel cells, and by this they are an essential contribution to environmental integrity. Also, this point of view makes clear that the driving force of materials development is the application, integrating future requirements and the visions from research. (orig.) [de

JNK signaling pathway regulates sorbitol-induced Tau proteolysis and apoptosis in SH-SY5Y cells by targeting caspase-3.

Science.gov (United States)

Olivera Santa-Catalina, Marta; Caballero Bermejo, Montaña; Argent, Ricardo; Alonso, Juan C; Centeno, Francisco; Lorenzo, María J

2017-12-15

Growing evidence suggests that Diabetes Mellitus increases the risk of developing Alzheimer's disease. It is well known that hyperglycemia, a key feature of Diabetes Mellitus, may induce plasma osmolarity disturbances. Both hyperglycemia and hyperosmolarity promote the altered post-translational regulation of microtubule-associated protein Tau. Interestingly, abnormal hyperphosphorylation and cleavage of Tau have been proven to lead to the genesis of filamentous structures referred to as neurofibrillary tangles, the main pathological hallmark of Alzheimer's disease. We have previously described that hyperosmotic stress induced by sorbitol promotes Tau proteolysis and apoptosis in SH-SY5Y cells via caspase-3 activation. In order to gain insights into the regulatory mechanisms of such processes, in this work we explored the intracellular signaling pathways that regulate these events. We found that sorbitol treatment significantly enhanced the activation of conventional families of MAPK in SH-SY5Y cells. Tau proteolysis was completely prevented by JNK inhibition but not affected by either ERK1/2 or p38 MAPK blockade. Moreover, inhibition of JNK, but not ERK1/2 or p38 MAPK, efficiently prevented sorbitol-induced apoptosis and caspase-3 activation. In summary, we provide evidence that JNK signaling pathway is an upstream regulator of hyperosmotic stress-induced Tau cleavage and apoptosis in SH-SY5Y through the control of caspase-3 activation. Copyright © 2017 Elsevier Inc. All rights reserved.

46 CFR 112.50-5 - Electric starting.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Electric starting. 112.50-5 Section 112.50-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Diesel and Gas Turbine Engine Driven Generator Sets § 112.50-5 Electric starting...

The view of the geotechnical engineering on the radioactive waste disposal