International Nuclear Information System (INIS)
Mould, Richard F.
1995-01-01
Purpose/Objective: To explain some of the most useful statistical calculation procedures which are relevant to radiation oncologists and to provide insights on what tests and procedures should be used in various situations such as when survival rates and their associated standard errors have to be determined. To describe some of the problems and pitfalls in clinical trial designs which have to be overcome if a trial is to have the possibility of reaching a successful conclusion. To review methods of computing criteria to quantitatively describe criteria of success (eg. quality of life, long-term survival, cure) of radiation oncology and to suggest possible future statistical improvements in this area. Chi-Squared Test: The chi-squared test is probably the most useful of the tests of statistical significance for the radiation oncologist. Applications will be described, including goodness of fit tests and 2x2 contingency tables which are the simplest of the generalized nxm contingency tables. Degrees of Freedom and P<0.05 for Significance Testing: An Introduction will be given to the meaning of P<0.05 in relation to significance testing and the use of tables of critical values of a test statistic (eg. chi-squared) which are given as a function of degrees of freedom and P-values. Survival Rate Calculations for Grouped and Ungrouped Data: The life-table method (sometimes termed the actuarial method) will be explained for both grouped data (eg. survival times grouped in annual intervals for patients who have died and for those who are still alive or lost to follow-up) and for ungrouped data (when individual survival times are used). The method for ungrouped data is variously termed the Kaplan-Meier or Product Limit method. Logrank Test: This is the most useful test for comparison of the survival experience of two groups of patients and its use will be explained. In part the computation is similar to that for the Kaplan-Meier/Product Limit method
Energy Technology Data Exchange (ETDEWEB)
Mould, Richard F
1995-07-01
Purpose/Objective: To explain some of the most useful statistical calculation procedures which are relevant to radiation oncologists and to provide insights on what tests and procedures should be used in various situations such as when survival rates and their associated standard errors have to be determined. To describe some of the problems and pitfalls in clinical trial designs which have to be overcome if a trial is to have the possibility of reaching a successful conclusion. To review methods of computing criteria to quantitatively describe criteria of success (eg. quality of life, long-term survival, cure) of radiation oncology and to suggest possible future statistical improvements in this area. Chi-Squared Test: The chi-squared test is probably the most useful of the tests of statistical significance for the radiation oncologist. Applications will be described, including goodness of fit tests and 2x2 contingency tables which are the simplest of the generalized nxm contingency tables. Degrees of Freedom and P<0.05 for Significance Testing: An Introduction will be given to the meaning of P<0.05 in relation to significance testing and the use of tables of critical values of a test statistic (eg. chi-squared) which are given as a function of degrees of freedom and P-values. Survival Rate Calculations for Grouped and Ungrouped Data: The life-table method (sometimes termed the actuarial method) will be explained for both grouped data (eg. survival times grouped in annual intervals for patients who have died and for those who are still alive or lost to follow-up) and for ungrouped data (when individual survival times are used). The method for ungrouped data is variously termed the Kaplan-Meier or Product Limit method. Logrank Test: This is the most useful test for comparison of the survival experience of two groups of patients and its use will be explained. In part the computation is similar to that for the Kaplan-Meier/Product Limit method.
The rating reliability calculator
Directory of Open Access Journals (Sweden)
Solomon David J
2004-04-01
Full Text Available Abstract Background Rating scales form an important means of gathering evaluation data. Since important decisions are often based on these evaluations, determining the reliability of rating data can be critical. Most commonly used methods of estimating reliability require a complete set of ratings i.e. every subject being rated must be rated by each judge. Over fifty years ago Ebel described an algorithm for estimating the reliability of ratings based on incomplete data. While his article has been widely cited over the years, software based on the algorithm is not readily available. This paper describes an easy-to-use Web-based utility for estimating the reliability of ratings based on incomplete data using Ebel's algorithm. Methods The program is available public use on our server and the source code is freely available under GNU General Public License. The utility is written in PHP, a common open source imbedded scripting language. The rating data can be entered in a convenient format on the user's personal computer that the program will upload to the server for calculating the reliability and other statistics describing the ratings. Results When the program is run it displays the reliability, number of subject rated, harmonic mean number of judges rating each subject, the mean and standard deviation of the averaged ratings per subject. The program also displays the mean, standard deviation and number of ratings for each subject rated. Additionally the program will estimate the reliability of an average of a number of ratings for each subject via the Spearman-Brown prophecy formula. Conclusion This simple web-based program provides a convenient means of estimating the reliability of rating data without the need to conduct special studies in order to provide complete rating data. I would welcome other researchers revising and enhancing the program.
Starck, Patricia L; Love, Karen; McPherson, Robert
2008-01-01
In recent years, the focus has been on increasing the number of registered nurse (RN) graduates. Numerous states have initiated programs to increase the number and quality of students entering nursing programs, and to expand the capacity of their programs to enroll additional qualified students. However, little attention has been focused on an equally, if not more, effective method for increasing the number of RNs produced-increasing the graduation rate of students enrolling. This article describes a project that undertook the task of compiling graduation data for 15 entry-level programs, standardizing terms and calculations for compiling the data, and producing a regional report on graduation rates of RN students overall and by type of program. Methodology is outlined in this article. This effort produced results that were surprising to program deans and directors and is expected to produce greater collaborative efforts to improve these rates both locally and statewide.
DEFF Research Database (Denmark)
Bille, Trine; Jensen, Søren
2017-01-01
The literature of cultural economics generally finds that an artistic education has no significant impact on artists’ income and careers in the arts. In our research, we have readdressed this question by looking at the artists’ survival in the arts occupations. The results show that an artistic...... education has a significant impact on artists’ careers in the arts and we find important industry differences....
Directory of Open Access Journals (Sweden)
Jan Norum
2017-12-01
Full Text Available Introduction: Acute myocardial infarction (AMI is a potentially deadly disease and significant efforts have been concentrated on improving hospital performance. A 30-day survival rate has become a key quality of care indicator. In Northern Norway, some patients undergoing AMI are directly transferred to the Regional Cardiac Intervention Center at the University Hospital of North Norway in Tromsø. Here, coronary angiography and percutaneous coronary intervention is performed. Consequently, local hospitals may be bypassed in the treatment chain, generating differences in case mix, and making the treatment chain model difficult to interpret. We aimed to compare the treatment chain model with an alternative based on patients’ place of living. Methods: Between 2013 and 2015, a total of 3,155 patients were registered in the Norwegian Patient Registry database. All patients were categorized according to their local hospital’s catchment area. The method of Guo-Romano, with an indifference interval of 0.02, was used to test whether a hospital was an outlier or not. We adjusted for age, sex, comorbidity, and number of prior hospitalizations. Conclusions: We revealed the 30-day AMI survival figure ranging between 88.0% and 93.5% (absolute difference 5.5% using the hospital catchment method. The treatment chain rate ranged between 86.0% and 94.0% (absolute difference 8.0%. The latter figure is the one published as the National Quality of Care Measure in Norway. Local hospitals may get negative attention even though their catchment area is well served. We recommend the hospital catchment method as the first choice when measuring equality of care.
Tank Z-361 dose rate calculations
International Nuclear Information System (INIS)
Richard, R.F.
1998-01-01
Neutron and gamma ray dose rates were calculated above and around the 6-inch riser of tank Z-361 located at the Plutonium Finishing Plant. Dose rates were also determined off of one side of the tank. The largest dose rate 0.029 mrem/h was a gamma ray dose and occurred 76.2 cm (30 in.) directly above the open riser. All other dose rates were negligible. The ANSI/ANS 1991 flux to dose conversion factor for neutrons and photons were used in this analysis. Dose rates are reported in units of mrem/h with the calculated uncertainty shown within the parentheses
Fair and Reasonable Rate Calculation Data -
Department of Transportation — This dataset provides guidelines for calculating the fair and reasonable rates for U.S. flag vessels carrying preference cargoes subject to regulations contained at...
Changing Survival Rate of Infants Born Before 26 Gestational Weeks
Rahman, Asad; Abdellatif, Mohamed; Sharef, Sharef W.; Fazalullah, Muhammad; Al-Senaidi, Khalfan; Khan, Ashfaq A.; Ahmad, Masood; Kripail, Mathew; Abuanza, Mazen; Bataclan, Flordeliza
2015-01-01
Objectives: This study aimed to evaluate the changing survival rate and morbidities among infants born before 26 gestational weeks at the Sultan Qaboos University Hospital (SQUH) in Muscat, Oman. Methods: This retrospective study assessed the mortality and morbidities of all premature infants born alive at 23–26 gestational weeks at SQUH between June 2006 and May 2013. Infants referred to SQUH within 72 hours of birth during this period were also included. Electronic records were reviewed for gestational age, gender, birth weight, maternal age, mode and place of delivery, antenatal steroid administration, morbidity and outcome. The survival rate was calculated and findings were then compared with those of a previous study conducted in the same hospital from 1991 to 1998. Rates of major morbidities were also calculated. Results: A total of 81 infants between 23–26 gestational weeks were admitted to the neonatal unit during the study period. Of these, 58.0% were male and 42.0% were female. Median gestational age was 25 weeks and mean birth weight was 770 ± 150 g. Of the 81 infants, 49 survived. The overall survival rate was 60.5% compared to 41% reported in the previous study. Respiratory distress syndrome (100.0%), retinopathy of prematurity (51.9%), bronchopulmonary dysplasia (34.6%), intraventricular haemorrhage (30.9%) and patent ductus arteriosus (28.4%) were the most common morbidities. Conclusion: The overall survival rate of infants between 23–26 gestational weeks during the study period had significantly improved in comparison to that found at the same hospital from 1991 to 1998. There is a need for the long-term neurodevelopmental follow-up of premature infants. PMID:26357555
Reaction rate calculations via transmission coefficients
International Nuclear Information System (INIS)
Feit, M.D.; Alder, B.J.
1985-01-01
The transmission coefficient of a wavepacket traversing a potential barrier can be determined by steady state calculations carried out in imaginary time instead of by real time dynamical calculations. The general argument is verified for the Eckart barrier potential by a comparison of transmission coefficients calculated from real and imaginary time solutions of the Schroedinger equation. The correspondence demonstrated here allows a formulation for the reaction rate that avoids difficulties due to both rare events and explicitly time dependent calculations. 5 refs., 2 figs
Dose rate calculations for a reconnaissance vehicle
International Nuclear Information System (INIS)
Grindrod, L.; Mackey, J.; Salmon, M.; Smith, C.; Wall, S.
2005-01-01
A Chemical Nuclear Reconnaissance System (CNRS) has been developed by the British Ministry of Defence to make chemical and radiation measurements on contaminated terrain using appropriate sensors and recording equipment installed in a land rover. A research programme is under way to develop and validate a predictive capability to calculate the build-up of contamination on the vehicle, radiation detector performance and dose rates to the occupants of the vehicle. This paper describes the geometric model of the vehicle and the methodology used for calculations of detector response. Calculated dose rates obtained using the MCBEND Monte Carlo radiation transport computer code in adjoint mode are presented. These address the transient response of the detectors as the vehicle passes through a contaminated area. Calculated dose rates were found to agree with the measured data to be within the experimental uncertainties, thus giving confidence in the shielding model of the vehicle and its application to other scenarios. (authors)
Nesting success and survival rates of suburban Olive Thrushes ...
African Journals Online (AJOL)
Reproductive rate, clutch size, nesting success and survival rate of dependent fledglings were estimated from breeding records in the Eastern Cape. These data were used to estimate survival rate of independent fledglings. The estimated adult survival rate in this region was high and the clutch size was small, compared to ...
Biased Brownian dynamics for rate constant calculation.
Zou, G; Skeel, R D; Subramaniam, S
2000-01-01
An enhanced sampling method-biased Brownian dynamics-is developed for the calculation of diffusion-limited biomolecular association reaction rates with high energy or entropy barriers. Biased Brownian dynamics introduces a biasing force in addition to the electrostatic force between the reactants, and it associates a probability weight with each trajectory. A simulation loses weight when movement is along the biasing force and gains weight when movement is against the biasing force. The sampl...
Glass dissolution rate measurement and calculation revisited
Energy Technology Data Exchange (ETDEWEB)
Fournier, Maxime, E-mail: maxime.fournier@cea.fr [CEA, DEN, DTCD, SECM, F-30207, Bagnols sur Cèze (France); Ull, Aurélien; Nicoleau, Elodie [CEA, DEN, DTCD, SECM, F-30207, Bagnols sur Cèze (France); Inagaki, Yaohiro [Department of Applied Quantum Physics & Nuclear Engineering, Kyushu University, Fukuoka, 819-0395 (Japan); Odorico, Michaël [ICSM-UMR5257 CEA/CNRS/UM2/ENSCM, Site de Marcoule, BP17171, F-30207, Bagnols sur Cèze (France); Frugier, Pierre; Gin, Stéphane [CEA, DEN, DTCD, SECM, F-30207, Bagnols sur Cèze (France)
2016-08-01
Aqueous dissolution rate measurements of nuclear glasses are a key step in the long-term behavior study of such waste forms. These rates are routinely normalized to the glass surface area in contact with solution, and experiments are very often carried out using crushed materials. Various methods have been implemented to determine the surface area of such glass powders, leading to differing values, with the notion of the reactive surface area of crushed glass remaining vague. In this study, around forty initial dissolution rate measurements were conducted following static and flow rate (SPFT, MCFT) measurement protocols at 90 °C, pH 10. The international reference glass (ISG), in the forms of powders with different particle sizes and polished monoliths, and soda-lime glass beads were examined. Although crushed glass grains clearly cannot be assimilated with spheres, it is when using the samples geometric surface (S{sub geo}) that the rates measured on powders are closest to those found for monoliths. Overestimation of the reactive surface when using the BET model (S{sub BET}) may be due to small physical features at the atomic scale—contributing to BET surface area but not to AFM surface area. Such features are very small compared with the thickness of water ingress in glass (a few hundred nanometers) and should not be considered in rate calculations. With a S{sub BET}/S{sub geo} ratio of 2.5 ± 0.2 for ISG powders, it is shown here that rates measured on powders and normalized to S{sub geo} should be divided by 1.3 and rates normalized to S{sub BET} should be multiplied by 1.9 in order to be compared with rates measured on a monolith. The use of glass beads indicates that the geometric surface gives a good estimation of glass reactive surface if sample geometry can be precisely described. Although data clearly shows the repeatability of measurements, results must be given with a high uncertainty of approximately ±25%. - Highlights: • Initial dissolution
Scientific periodical publications rating's calculation and analysis
Directory of Open Access Journals (Sweden)
B. E. Nikitin
2017-01-01
Full Text Available The article considers the constructing problem of the food industry journals aggregate ratings. The streamlines of the seventeen magazines on four bibliometric indexes (SCIENCE INDEX, five-year impact factor RISC given the translated version without self-citations, h-index over 10 years and Herfindahl index, which are used in the scientific electronic library elibrary.ru was used as initial data. The statement of the problem refers to multi-criteria decision-making problems. Ranking the journals in these indexes are different from each other because bibliometric indicators account different aspects of the journals. The classical approach to thisproblems solution is based on generalized criterion building in the form of an additive convolution. However, this approach requires adherence to a number of regular conditions that may not always be performed when the practical problems solution. The reductionspossibility of the considered formulation in the form of multi-criteria decision-making tasks to the problem of collective choice. The aggregated ratings of the reporting journals are calculated by using the three social choice rules – Board procedure, Copeland procedures and Kemeny median heuristic procedures. On the basis of Spearman's rank correlation determined the quantitative evaluation of the degree of intimacy built in magazines. In particular, calculated on the basis of procedure, Board and Kemeny median aggregate ratings reporting in the logs coincided. The results showed that the constructed ordering of journals on the basis of social choice rules are in good agreement with the scientific electronic library (eLIBRARY bibliometric indicators.
Data on empirically estimated corporate survival rate in Russia.
Kuzmin, Evgeny A
2018-02-01
The article presents data on the corporate survival rate in Russia in 1991-2014. The empirical survey was based on a random sample with the average number of non-repeated observations (number of companies) for the survey each year equal to 75,958 (24,236 minimum and 126,953 maximum). The actual limiting mean error ∆ p was 2.24% with 99% integrity. The survey methodology was based on a cross joining of various formal periods in the corporate life cycles (legal and business), which makes it possible to talk about a conventionally active time life of companies' existence with a number of assumptions. The empirical survey values were grouped by Russian regions and industries according to the classifier and consolidated into a single database for analysing the corporate life cycle and their survival rate and searching for deviation dependencies in calculated parameters. Preliminary and incomplete figures were available in the paper entitled "Survival Rate and Lifecycle in Terms of Uncertainty: Review of Companies from Russia and Eastern Europe" (Kuzmin and Guseva, 2016) [3]. The further survey led to filtered processed data with clerical errors excluded. These particular values are available in the article. The survey intended to fill a fact-based gap in various fundamental surveys that involved matters of the corporate life cycle in Russia within the insufficient statistical framework. The data are of interest for an analysis of Russian entrepreneurship, assessment of the market development and incorporation risks in the current business environment. A further heuristic potential is achievable through an ability of forecasted changes in business demography and model building based on the representative data set.
Investigation of survival rate of trees planted in agroforestry and ...
African Journals Online (AJOL)
Low survival rate of trees planted during annual planting campaigns is often reported in many parts of the country and there is need to understand why and propose adequate solutions to improve survival rate of trees in plantation. The study was conducted in three sectors of Huye District namely Mukura, Tumba and Ngoma ...
Survival Rate of Limb Replantation in Different Age Groups.
Tatebe, Masahiro; Urata, Shiro; Tanaka, Kenji; Kurahashi, Toshikazu; Takeda, Shinsuke; Hirata, Hitoshi
2017-08-01
Revascularization of damaged limbs/digits is technically feasible, but indications for surgical replantation remain controversial. The authors analyzed the survival rate of upper limb amputations and the associated factors in different age groups. They grouped 371 limb/digit amputees (average age, 44 years; range, 2-85 years) treated in their hospital during the past 10 years into three groups based on age (young, ≤ 15 years, n = 12; adult, 16-64 years, n = 302; elderly, ≥ 65 years, n = 57) and analyzed their injury type (extent of injury and stump status), operation method, presence of medical complications (Charlson comorbidity index), and survival rate. There were 168 replantations, and the overall replantation survival rate was 93%. The Charlson comorbidity index of the replantation patients was 0 in 124 cases; 1 in 32; 2 in 9; and 3 in 3, but it did not show any significant difference in survival rate after replantation. Eight elderly patients (14%) did not opt for replantation. Younger patients tended to undergo replantation, but they had lower success rates due to their severe injury status. The results of this study show that the survival rate of replantation in elderly patients is equal to that in adults. Stump evaluation is important for survival, but the presence of medical complications is not associated with the overall survival rate.
Condon, John R; Zhang, Xiaohua; Baade, Peter; Griffiths, Kalinda; Cunningham, Joan; Roder, David M; Coory, Michael; Jelfs, Paul L; Threlfall, Tim
2014-01-31
National cancer survival statistics are available for the total Australian population but not Indigenous Australians, although their cancer mortality rates are known to be higher than those of other Australians. We aimed to validate analysis methods and report cancer survival rates for Indigenous Australians as the basis for regular national reporting. We used national cancer registrations data to calculate all-cancer and site-specific relative survival for Indigenous Australians (compared with non-Indigenous Australians) diagnosed in 2001-2005. Because of limited availability of Indigenous life tables, we validated and used cause-specific survival (rather than relative survival) for proportional hazards regression to analyze time trends and regional variation in all-cancer survival between 1991 and 2005. Survival was lower for Indigenous than non-Indigenous Australians for all cancers combined and for many cancer sites. The excess mortality of Indigenous people with cancer was restricted to the first three years after diagnosis, and greatest in the first year. Survival was lower for rural and remote than urban residents; this disparity was much greater for Indigenous people. Survival improved between 1991 and 2005 for non-Indigenous people (mortality decreased by 28%), but to a much lesser extent for Indigenous people (11%) and only for those in remote areas; cancer survival did not improve for urban Indigenous residents. Cancer survival is lower for Indigenous than other Australians, for all cancers combined and many individual cancer sites, although more accurate recording of Indigenous status by cancer registers is required before the extent of this disadvantage can be known with certainty. Cancer care for Indigenous Australians needs to be considerably improved; cancer diagnosis, treatment, and support services need to be redesigned specifically to be accessible and acceptable to Indigenous people.
Survival rates of birds of tropical and temperate forests: will the dogma survive?
Karr, J.R.; Nichols, J.D.; Klimkiewicz, M.K.; Brawn, J.D.
1990-01-01
Survival rates of tropical forest birds are widely assumed to be high relative to the survival rates of temperate forest birds. Much life-history theory is based on this assumption despite the lack of empirical data to support it. We provide the first detailed comparison of survival rates of tropical and temperate forest birds based on extensive data bases and modern capture-recapture models. We find no support for the conventional wisdom. Because clutch size is only one component of reproductive rate, the frequently assumed, simple association between clutch size and adult survival rates should not necessarily be expected. Our results emphasize the need to consider components of fecundity in addition to clutch size when comparing the life histories of tropical and temperate birds and suggest similar considerations in the development of vertebrate life-history theory.
Nonsurgical factors of digital replantation and survival rate A metaanalysis
Directory of Open Access Journals (Sweden)
Huawei Yu
2015-01-01
Full Text Available The aim of this metaanalysis was to evaluate the association between nonsurgical factors and survival rate of digital replantation. A computer search of MEDLINE, OVID, EMBASE and CNKI databases was conducted to identify literatures for digital replantation, with the keywords of "digit," "finger" and "replantation" from their inception to June 10, 2014. Based on the inclusion and exclusion criteria, data were extracted independently by two authors using piloted forms. Review Manager 5.2 software was used for data analysis. The effect of some nonsurgical factors (gender, age, amputated finger, injury mechanisms, ischemia time and the way of preservation on the survival rate of digital replantation was assessed. The metaanalysis result suggested that gender and ischemia time had no significant influence on the survival rate of amputation replantation. However, the survival rate of digital replantation of adults was significantly higher than that of children. The guillotine injury of a finger was easier to replant successfully than the crush and avulsion. The little finger was more difficult for replantation than thumb. Survival rate of fingers stored in low temperature was higher than that in common temperature. The present metaanalysis suggested that age, injury mechanism, amputated finger and the way of preservation were significantly associated with the survival rate of digital replantation.
Survival rate of breast cancer patients in Malaysia: a population-based study.
Abdullah, Nor Aini; Wan Mahiyuddin, Wan Rozita; Muhammad, Nor Asiah; Ali, Zainudin Mohamad; Ibrahim, Lailanor; Ibrahim Tamim, Nor Saleha; Mustafa, Amal Nasir; Kamaluddin, Muhammad Amir
2013-01-01
Breast cancer is the most common cancer among Malaysian women. Other than hospital-based results, there are no documented population-based survival rates of Malaysian women for breast cancers. This population- based retrospective cohort study was therefore conducted. Data were obtained from Health Informatics Centre, Ministry of Health Malaysia, National Cancer Registry and National Registration Department for the period from 1st Jan 2000 to 31st December 2005. Cases were captured by ICD-10 and linked to death certificates to identify the status. Only complete data were analysed. Survival time was calculated from the estimated date of diagnosis to the date of death or date of loss to follow-up. Observed survival rates were estimated by Kaplan- Meier method using SPSS Statistical Software version 17. A total of 10,230 complete data sets were analysed. The mean age at diagnosis was 50.6 years old. The overall 5-year survival rate was 49% with median survival time of 68.1 months. Indian women had a higher survival rate of 54% compared to Chinese women (49%) and Malays (45%). The overall 5-year survival rate of breast cancer patient among Malaysian women was still low for the cohort of 2000 to 2005 as compared to survival rates in developed nations. Therefore, it is necessary to enhance the strategies for early detection and intervention.
Survival and maturation rates of the African rodent Mastomys natalensis
DEFF Research Database (Denmark)
Sluydts, Vincent; Crespin, Laurent; Davis, Stephen
2008-01-01
the model fit. On the other hand we showed that maturation rates were correlated negatively with density the previous month and positively to cumulative rainfall over the past three months. Survival estimates of both adults and subadults varied seasonally, with higher estimates during the increase phase......Survival and maturation rates of female Mastomys natalensis were analysed based on a ten-year onthly capture-recapture data set. We investigated whether direct and delayed density dependent and independent (rainfall) variables accounted for the considerable variation in demographic traits....... It was estimated that seasonal and annual covariates accounted for respectively 29 and 26% of the total variation in maturation rates and respectively 17 and 11% of the variation in survival rates. Explaining the between-year differences in maturation rates with annual past rainfall or density did not improve...
Database crime to crime match rate calculation.
Buckleton, John; Bright, Jo-Anne; Walsh, Simon J
2009-06-01
Guidance exists on how to count matches between samples in a crime sample database but we are unable to locate a definition of how to estimate a match rate. We propose a method that does not proceed from the match counting definition but which has a strong logic.
49 CFR 1141.1 - Procedures to calculate interest rates.
2010-10-01
... the portion of the year covered by the interest rate. A simple multiplication of the nominal rate by... 49 Transportation 8 2010-10-01 2010-10-01 false Procedures to calculate interest rates. 1141.1... TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE PROCEDURES TO CALCULATE INTEREST RATES...
Calculating the Rate of Senescence From Mortality Data
DEFF Research Database (Denmark)
Koopman, Jacob J E; Rozing, Maarten P; Kramer, Anneke
2016-01-01
, they do not fit mortality rates at young and old ages. Therefore, we developed a method to calculate senescence rates from the acceleration of mortality directly without modeling the mortality rates. We applied the different methods to age group-specific mortality data from the European Renal Association......, the rate of senescence can be calculated directly from non-modeled mortality rates, overcoming the disadvantages of an indirect estimation based on modeled mortality rates....
Magaji, Bello Arkilla; Moy, Foong Ming; Roslani, April Camilla; Law, Chee Wei
2017-05-18
Colorectal cancer is the third most commonly diagnosed malignancy and the fourth leading cause of cancer-related death globally. It is the second most common cancer among both males and females in Malaysia. The economic burden of colorectal cancer is likely to increase over time owing to its current trend and aging population. Cancer survival analysis is an essential indicator for early detection and improvement in cancer treatment. However, there was a scarcity of studies concerning survival of colorectal cancer patients as well as its predictors. Therefore, we aimed to determine the 1-, 3- and 5-year survival rates, compare survival rates among ethnic groups and determine the predictors of survival among colorectal cancer patients. This was an ambidirectional cohort study conducted at the University Malaya Medical Centre (UMMC) in Kuala Lumpur, Malaysia. All Malaysian citizens or permanent residents with histologically confirmed diagnosis of colorectal cancer seen at UMMC from 1 January 2001 to 31 December 2010 were included in the study. Demographic and clinical characteristics were extracted from the medical records. Patients were followed-up until death or censored at the end of the study (31st December 2010). Censored patients' vital status (whether alive or dead) were cross checked with the National Registration Department. Survival analyses at 1-, 3- and 5-year intervals were performed using the Kaplan-Meier method. Log-rank test was used to compare the survival rates, while Cox proportional hazard regression analysis was carried out to determine the predictors of 5-year colorectal cancer survival. Among 1212 patients, the median survival for colorectal, colon and rectal cancers were 42.0, 42.0 and 41.0 months respectively; while the 1-, 3-, and 5-year relative survival rates ranged from 73.8 to 76.0%, 52.1 to 53.7% and 40.4 to 45.4% respectively. The Chinese patients had the lowest 5-year survival compared to Malay and Indian patients. Based on the 814
Water application rate and frequency affect seedling survival and ...
African Journals Online (AJOL)
Adequate amount of water is critical to successful tree nursery operation among resource-constrained smallholder farmers in Africa. Two experiments were undertaken with the objectives of evaluating effects of water application rate and frequency on seedling growth and survival of Persea americana and Vangueria ...
Survival rates in bankruptcy systems : overlooking the evidence
Couwenberg, Oscar
2001-01-01
Extensive research on bankruptcy still has not made it possible to end the efficiency discussion concerning the need for a reorganization provision in bankruptcy laws. In this paper, I discuss the pervasiveness of asset sales in bankruptcy procedures and the effect it has on survival rates. Without
Assessing the reliability of calculated catalytic ammonia synthesis rates
DEFF Research Database (Denmark)
Medford, Andrew James; Wellendorff, Jess; Vojvodic, Aleksandra
2014-01-01
We introduce a general method for estimating the uncertainty in calculated materials properties based on density functional theory calculations. We illustrate the approach for a calculation of the catalytic rate of ammonia synthesis over a range of transition-metal catalysts. The correlation...... between errors in density functional theory calculations is shown to play an important role in reducing the predicted error on calculated rates. Uncertainties depend strongly on reaction conditions and catalyst material, and the relative rates between different catalysts are considerably better described...
Adult survival and population growth rate in Colorado big brown bats (Eptesicus fuscus)
O'Shea, T.J.; Ellison, L.E.; Stanley, T.R.
2011-01-01
We studied adult survival and population growth at multiple maternity colonies of big brown bats (Eptesicus fuscus) in Fort Collins, Colorado. We investigated hypotheses about survival using information-theoretic methods and mark-recapture analyses based on passive detection of adult females tagged with passive integrated transponders. We constructed a 3-stage life-history matrix model to estimate population growth rate (??) and assessed the relative importance of adult survival and other life-history parameters to population growth through elasticity and sensitivity analysis. Annual adult survival at 5 maternity colonies monitored from 2001 to 2005 was estimated at 0.79 (95% confidence interval [95% CI] = 0.77-0.82). Adult survival varied by year and roost, with low survival during an extreme drought year, a finding with negative implications for bat populations because of the likelihood of increasing drought in western North America due to global climate change. Adult survival during winter was higher than in summer, and mean life expectancies calculated from survival estimates were lower than maximum longevity records. We modeled adult survival with recruitment parameter estimates from the same population. The study population was growing (?? = 1.096; 95% CI = 1.057-1.135). Adult survival was the most important demographic parameter for population growth. Growth clearly had the highest elasticity to adult survival, followed by juvenile survival and adult fecundity (approximately equivalent in rank). Elasticity was lowest for fecundity of yearlings. The relative importances of the various life-history parameters for population growth rate are similar to those of large mammals. ?? 2011 American Society of Mammalogists.
Dose-rate dependent stochastic effects in radiation cell-survival models
International Nuclear Information System (INIS)
Sachs, R.K.; Hlatky, L.R.
1990-01-01
When cells are subjected to ionizing radiation the specific energy rate (microscopic analog of dose-rate) varies from cell to cell. Within one cell, this rate fluctuates during the course of time; a crossing of a sensitive cellular site by a high energy charged particle produces many ionizations almost simultaneously, but during the interval between events no ionizations occur. In any cell-survival model one can incorporate the effect of such fluctuations without changing the basic biological assumptions. Using stochastic differential equations and Monte Carlo methods to take into account stochastic effects we calculated the dose-survival rfelationships in a number of current cell survival models. Some of the models assume quadratic misrepair; others assume saturable repair enzyme systems. It was found that a significant effect of random fluctuations is to decrease the theoretically predicted amount of dose-rate sparing. In the limit of low dose-rates neglecting the stochastic nature of specific energy rates often leads to qualitatively misleading results by overestimating the surviving fraction drastically. In the opposite limit of acute irradiation, analyzing the fluctuations in rates merely amounts to analyzing fluctuations in total specific energy via the usual microdosimetric specific energy distribution function, and neglecting fluctuations usually underestimates the surviving fraction. The Monte Carlo methods interpolate systematically between the low dose-rate and high dose-rate limits. As in other approaches, the slope of the survival curve at low dose-rates is virtually independent of dose and equals the initial slope of the survival curve for acute radiation. (orig.)
SURVIVAL RATE PENYANDANG HIPERTENSI DENGAN KONSUMSI NATRIUM RENDAH TERHADAP KEJADIAN STROKE
Directory of Open Access Journals (Sweden)
Ekowati Rahajeng
2017-01-01
Full Text Available Stroke is the leading cause of death and disability in the world. Several studies have shown that stroke can be prevented through modifiable risk factors. The adequate treatment of hypertension may reduce the risk of stroke. Lifestyle modification such as reducing salt intake in hypertension management have demonstrated lowering blood pressure, enhancing the effectiveness of antihypertension drugs and also reducing stroke risk. This study aims to verify the survival rate of hypertension with lower sodium intake (<2000 mg per day on the incidence of stroke. The study was conducted through a prospective cohort study (4 years of follow-up in 1082 people with confirmed hypertension. Stroke were confirmed by neurologist. The consumption of sodium, sugar and fat were collected through 24-hour dietary recall. Hypertension survival rate was calculated using Life Table Survival analysis. This study has demonstrated evidence of the higher survival rate of hypertension with low sodium intake on the incidence of stroke, with the difference 2-year survival rate is 3 percent higher and 4-year survival rate is 5 percent higher. Sodium consumption of <2000 mg per day in people with hypertension has prevented a 78 percent incidence of stroke. Therefore, the intervention programs to reduce of the consumption of salt or sodium in Indonesia should be prioritized.
Updates to In-Line Calculation of Photolysis Rates
How photolysis rates are calculated affects ozone and aerosol concentrations predicted by the CMAQ model and the model?s run-time. The standard configuration of CMAQ uses the inline option that calculates photolysis rates by solving the radiative transfer equation for the needed ...
Effects of non-surgical factors on digital replantation survival rate: a meta-analysis.
Ma, Z; Guo, F; Qi, J; Xiang, W; Zhang, J
2016-02-01
This study aimed to evaluate the risk factors affecting survival rate of digital replantation by a meta-analysis. A computer retrieval of MEDLINE, OVID, EMBASE, and CNKI databases was conducted to identify citations for digital replantation with digit or finger or thumb or digital or fingertip and replantation as keywords. RevMan 5.2 software was used to calculate the pooled odds ratios. In total, there were 4678 amputated digits in 2641 patients. Gender and ischemia time had no significant influence on the survival rate of amputation replantation (P > 0.05). Age, injured hand, injury type, zone, and the method of preservation the amputated digit significantly influence the survival rate of digital replantation (P < 0.05). Children, right hand, crush, or avulsion and little finger are the risk factors that adversely affect the outcome. Level 5*. © The Author(s) 2015.
Contribution of screening and survival differences to racial disparities in colorectal cancer rates
Lansdorp-Vogelaar, Iris; Kuntz, Karen M.; Knudsen, Amy B.; van Ballegooijen, Marjolein; Zauber, Ann G.; Jemal, Ahmedin
2012-01-01
Background Considerable disparities exist in colorectal cancer (CRC) incidence and mortality rates between blacks and whites in the US. We estimated how much of these disparities could be explained by differences in CRC screening and stage-specific relative CRC survival. Methods We used the MISCAN-Colon microsimulation model to estimate CRC incidence and mortality rates in blacks aged 50 years and older from 1975 to 2007 assuming they had: 1) the same trends in screening rates as whites instead of observed screening rates (incidence and mortality); and 2) the same trends in stage-specific relative CRC survival rates as whites instead of observed (mortality only); and 3) a combination of both. The racial disparities in CRC incidence and mortality rates attributable to differences in screening and/or stage-specific relative CRC survival were then calculated by comparing rates from these scenarios to the observed black rates. Results Differences in screening account for 42% of disparity in CRC incidence and 19% of disparity in CRC mortality between blacks and whites. 36% of the disparity in CRC mortality could be attributed to differences in stage-specific relative CRC survival. Together screening and survival explained a little over 50% of the disparity in CRC mortality between blacks and whites. Conclusion Differences in screening and relative CRC survival are responsible for a considerable proportion of the observed disparities in CRC incidence and mortality rates between blacks and whites. Impact Enabling blacks to achieve equal access to care as whites could substantially reduce the racial disparities in CRC burden. PMID:22514249
Dose Rate Calculations for Rotary Mode Core Sampling Exhauster
Foust, D J
2000-01-01
This document provides the calculated estimated dose rates for three external locations on the Rotary Mode Core Sampling (RMCS) exhauster HEPA filter housing, per the request of Characterization Field Engineering.
Dose Rate Calculations for Rotary Mode Core Sampling Exhauster
International Nuclear Information System (INIS)
FOUST, D.J.
2000-01-01
This document provides the calculated estimated dose rates for three external locations on the Rotary Mode Core Sampling (RMCS) exhauster HEPA filter housing, per the request of Characterization Field Engineering
Calculating stocking rates for game ranches: substitution ratios for ...
African Journals Online (AJOL)
Calculating stocking rates for game ranches: substitution ratios for use in the Mopani ... Reports on a study conducted to quantify the overlap in ungulate resource-use on a game ranch, and to demonstrate how ... AJOL African Journals Online.
Directory of Open Access Journals (Sweden)
Yousef Veisani
2017-02-01
Full Text Available Context Resent reviews have shown that about 18% of all child cancers are leukemia. Track of the survival rate can help researchers improve quality of life of patients through improving screening or discovery of better treatments. Objectives This review aimed at estimating the 5-year survival rates and associated factors of childhood leukemia in Iran. Data Sources We carried out a systematic review through search of relevant studies published in English (PubMed, Scopus, Google scholar, and ISI and Persian databases (Magiran, Medlib, SID, and Iran Medex. Study Selection The study included all epidemiologic studies that estimated survival rate in children with leukemia in Iran during years 2002 to 2015, and a standardized manner was used for extraction of information. Data Extraction The entire text or summary of all searched articles was extracted and then, related articles were selected, and irrelevant ones were excluded. Fixed and random effects models were calculated by the STATA using standard meta-analysis methods. Heterogeneity was assessed by I² statistics. Results The overall 5-year survival rate in patients with childhood leukemia in Iran was 0.65 (95% CI, 0.62 to 0.67, 10 studies, in the acute lymphoblastic leukemia (ALL subtype was 71.0% (95% CI: 68.0 to 74.0, and in the acute myeloid leukemia (AML subtype was 46.0%. Results of the meta analysis showed significant poor survival with relapse (heart rate (HR 1.59, 95% confidence interval (CI 1.27 to 1.98 and white blood count (WBC counts ≥ 50,000 (HR 2.92, 95% CI 1.23 to 4.60. Conclusions The results showed that 5-year survival rates in patients with AML were lower than patients with ALL. The results of this meta analysis strongly support the need for future research, action, and guidance for clinicians to improve health-related quality of life and outcomes for children with leukemia.
Epidemiological Data and Survival Rate of Removable Partial Dentures
Moreno, Amália; Haddad, Marcela Filié; Rocha, Eduardo Passos; Assunção, Wirley Gonçalves; Filho, Humberto Gennari; Santos, Emerson Gomes Dos; Sonego, Mariana Vilela; Santos, Daniela Micheline Dos
2016-01-01
Introduction The use of removable partial denture (RPD) is considered as low-cost and common treatment option to rehabilitate edentulous areas. Aim This study aimed to investigate the epidemiological data of patients rehabilitated with removable partial denture (RPD) in order to assess treatment survival rate and failures. Materials and Methods Epidemiological data and medical records of patients treated with RPD between 2007 and 2012 at the RPD discipline of a Brazilian University (Aracatuba Dental School- UNESP) were evaluated as well as dental records of patients who underwent RPD treatments (fabrication or repairs) between 2000 and 2010. Factors such as gender, age, presence of systemic disease, main complaint, edentulous arch, period and cause of denture replacement and the prosthesis characteristics were recorded. The chi-square test was used to assess the differences between the variables and the Kaplan Meyer to assess the survival of the RPDs evaluated. Results A total of 324 maxillary RPD and 432 mandibular RPD were fabricated. Most of the patients were women aging 41 to 60-year-old. The number of mandibular RPD Kennedy class I (26%) was statistically higher for the maxillary arch (p<.05). There was no association between main complaint to gender or the presence of systemic disease. The lingual plate was the most common major connector used in the mandible (32%). The main reason for altering the design of replaced RPDs were changes during treatment plan. Conclusion The number of patients who require RPD is large; most of RPDs are Kennedy Class I. A good treatment plan is very important for achieving a positive treatment outcome, and it is strictly related to the survival rate. PMID:27437367
Changing Survival Rate of Infants Born Before 26 Gestational Weeks; Single-centre study
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Asad Rahman
2015-08-01
Full Text Available Objectives: This study aimed to evaluate the changing survival rate and morbidities among infants born before 26 gestational weeks at the Sultan Qaboos University Hospital (SQUH in Muscat, Oman. Methods: This retrospective study assessed the mortality and morbidities of all premature infants born alive at 23–26 gestational weeks at SQUH between June 2006 and May 2013. Infants referred to SQUH within 72 hours of birth during this period were also included. Electronic records were reviewed for gestational age, gender, birth weight, maternal age, mode and place of delivery, antenatal steroid administration, morbidity and outcome. The survival rate was calculated and findings were then compared with those of a previous study conducted in the same hospital from 1991 to 1998. Rates of major morbidities were also calculated. Results: A total of 81 infants between 23–26 gestational weeks were admitted to the neonatal unit during the study period. Of these, 58.0% were male and 42.0% were female. Median gestational age was 25 weeks and mean birth weight was 770 ± 150 g. Of the 81 infants, 49 survived. The overall survival rate was 60.5% compared to 41% reported in the previous study. Respiratory distress syndrome (100.0%, retinopathy of prematurity (51.9%, bronchopulmonary dysplasia (34.6%, intraventricular haemorrhage (30.9% and patent ductus arteriosus (28.4% were the most common morbidities. Conclusion: The overall survival rate of infants between 23–26 gestational weeks during the study period had significantly improved in comparison to that found at the same hospital from 1991 to 1998. There is a need for the long-term neurodevelopmental follow-up of premature infants.
Changing Survival Rate of Infants Born Before 26 Gestational Weeks: Single-centre study.
Rahman, Asad; Abdellatif, Mohamed; Sharef, Sharef W; Fazalullah, Muhammad; Al-Senaidi, Khalfan; Khan, Ashfaq A; Ahmad, Masood; Kripail, Mathew; Abuanza, Mazen; Bataclan, Flordeliza
2015-08-01
This study aimed to evaluate the changing survival rate and morbidities among infants born before 26 gestational weeks at the Sultan Qaboos University Hospital (SQUH) in Muscat, Oman. This retrospective study assessed the mortality and morbidities of all premature infants born alive at 23-26 gestational weeks at SQUH between June 2006 and May 2013. Infants referred to SQUH within 72 hours of birth during this period were also included. Electronic records were reviewed for gestational age, gender, birth weight, maternal age, mode and place of delivery, antenatal steroid administration, morbidity and outcome. The survival rate was calculated and findings were then compared with those of a previous study conducted in the same hospital from 1991 to 1998. Rates of major morbidities were also calculated. A total of 81 infants between 23-26 gestational weeks were admitted to the neonatal unit during the study period. Of these, 58.0% were male and 42.0% were female. Median gestational age was 25 weeks and mean birth weight was 770 ± 150 g. Of the 81 infants, 49 survived. The overall survival rate was 60.5% compared to 41% reported in the previous study. Respiratory distress syndrome (100.0%), retinopathy of prematurity (51.9%), bronchopulmonary dysplasia (34.6%), intraventricular haemorrhage (30.9%) and patent ductus arteriosus (28.4%) were the most common morbidities. The overall survival rate of infants between 23-26 gestational weeks during the study period had significantly improved in comparison to that found at the same hospital from 1991 to 1998. There is a need for the long-term neurodevelopmental follow-up of premature infants.
Experiences with leak rate calculations methods for LBB application
International Nuclear Information System (INIS)
Grebner, H.; Kastner, W.; Hoefler, A.; Maussner, G.
1997-01-01
In this paper, three leak rate computer programs for the application of leak before break analysis are described and compared. The programs are compared to each other and to results of an HDR Reactor experiment and two real crack cases. The programs analyzed are PIPELEAK, FLORA, and PICEP. Generally, the different leak rate models are in agreement. To obtain reasonable agreement between measured and calculated leak rates, it was necessary to also use data from detailed crack investigations
Experiences with leak rate calculations methods for LBB application
Energy Technology Data Exchange (ETDEWEB)
Grebner, H.; Kastner, W.; Hoefler, A.; Maussner, G. [and others
1997-04-01
In this paper, three leak rate computer programs for the application of leak before break analysis are described and compared. The programs are compared to each other and to results of an HDR Reactor experiment and two real crack cases. The programs analyzed are PIPELEAK, FLORA, and PICEP. Generally, the different leak rate models are in agreement. To obtain reasonable agreement between measured and calculated leak rates, it was necessary to also use data from detailed crack investigations.
APUAMA: a software tool for reaction rate calculations.
Euclides, Henrique O; P Barreto, Patricia R
2017-06-01
APUAMA is a free software designed to determine the reaction rate and thermodynamic properties of chemical species of a reagent system. With data from electronic structure calculations, the APUAMA determine the rate constant with tunneling correction, such as Wigner, Eckart and small curvature, and also, include the rovibrational level of diatomic molecules. The results are presented in the form of Arrhenius-Kooij form, for the reaction rate, and the thermodynamic properties are written down in the polynomial form. The word APUAMA means "fast" in Tupi-Guarani Brazilian language, then the code calculates the reaction rate on a simple and intuitive graphic interface, the form fast and practical. As program output, there are several ASCII files with tabulated information for rate constant, rovibrational levels, energy barriers and enthalpy of reaction, Arrhenius-Kooij coefficient, and also, the option to the User save all graphics in BMP format.
Benchmark calculations of thermal reaction rates. I - Quantal scattering theory
Chatfield, David C.; Truhlar, Donald G.; Schwenke, David W.
1991-01-01
The thermal rate coefficient for the prototype reaction H + H2 yields H2 + H with zero total angular momentum is calculated by summing, averaging, and numerically integrating state-to-state reaction probabilities calculated by time-independent quantum-mechanical scattering theory. The results are very carefully converged with respect to all numerical parameters in order to provide high-precision benchmark results for confirming the accuracy of new methods and testing their efficiency.
On the relationship between tumour growth rate and survival in non-small cell lung cancer
Directory of Open Access Journals (Sweden)
Hitesh B. Mistry
2017-11-01
Full Text Available A recurrent question within oncology drug development is predicting phase III outcome for a new treatment using early clinical data. One approach to tackle this problem has been to derive metrics from mathematical models that describe tumour size dynamics termed re-growth rate and time to tumour re-growth. They have shown to be strong predictors of overall survival in numerous studies but there is debate about how these metrics are derived and if they are more predictive than empirical end-points. This work explores the issues raised in using model-derived metric as predictors for survival analyses. Re-growth rate and time to tumour re-growth were calculated for three large clinical studies by forward and reverse alignment. The latter involves re-aligning patients to their time of progression. Hence, it accounts for the time taken to estimate re-growth rate and time to tumour re-growth but also assesses if these predictors correlate to survival from the time of progression. I found that neither re-growth rate nor time to tumour re-growth correlated to survival using reverse alignment. This suggests that the dynamics of tumours up until disease progression has no relationship to survival post progression. For prediction of a phase III trial I found the metrics performed no better than empirical end-points. These results highlight that care must be taken when relating dynamics of tumour imaging to survival and that bench-marking new approaches to existing ones is essential.
Efficient calculation of atomic rate coefficients in dense plasmas
Aslanyan, Valentin; Tallents, Greg J.
2017-03-01
Modelling electron statistics in a cold, dense plasma by the Fermi-Dirac distribution leads to complications in the calculations of atomic rate coefficients. The Pauli exclusion principle slows down the rate of collisions as electrons must find unoccupied quantum states and adds a further computational cost. Methods to calculate these coefficients by direct numerical integration with a high degree of parallelism are presented. This degree of optimization allows the effects of degeneracy to be incorporated into a time-dependent collisional-radiative model. Example results from such a model are presented.
Calculation of gamma ray exposure rates from uranium ore bodies
International Nuclear Information System (INIS)
Thomson, J.E.; Wilson, O.J.
1980-02-01
The planning of operations associated with uranium mines often requires that estimates be made of the exposure rates from various ore bodies. A straight-forward method of calculating the exposure rate from an arbitrarily shaped body is presented. Parameters for the calculation are evaluated under the assumption of secular equilibrium of uranium with its daughters and that the uranium is uniformly distributed throughout an average soil mixture. The spectral distribution of the emitted gamma rays and the effect of air attenuation are discussed. Worked examples are given of typical situations encountered in uranium mines
Acute Myeloid Leukemia: analysis of epidemiological profile and survival rate.
de Lima, Mariana Cardoso; da Silva, Denise Bousfield; Freund, Ana Paula Ferreira; Dacoregio, Juliana Shmitz; Costa, Tatiana El Jaick Bonifácio; Costa, Imaruí; Faraco, Daniel; Silva, Maurício Laerte
2016-01-01
To describe the epidemiological profile and the survival rate of patients with acute myeloid leukemia (AML) in a state reference pediatric hospital. Clinical-epidemiological, observational, retrospective, descriptive study. The study included new cases of patients with AML, diagnosed between 2004 and 2012, younger than 15 years. Of the 51 patients studied, 84% were white; 45% were females and 55%, males. Regarding age, 8% were younger than 1 year, 47% were aged between 1 and 10 years, and 45% were older than 10 years. The main signs/symptoms were fever (41.1%), asthenia/lack of appetite (35.2%), and hemorrhagic manifestations (27.4%). The most affected extra-medullary site was the central nervous system (14%). In 47% of patients, the white blood cell (WBC) count was below 10,000/mm(3) at diagnosis. The minimal residual disease (MRD) was less than 0.1%, on the 15th day of treatment in 16% of the sample. Medullary relapse occurred in 14% of cases. When comparing the bone marrow MRD with the vital status, it was observed that 71.42% of the patients with type M3 AML were alive, as were 54.05% of those with non-M3 AML. The death rate was 43% and the main proximate cause was septic shock (63.6%). In this study, the majority of patients were male, white, and older than 1 year. Most patients with WBC count <10,000/mm(3) at diagnosis lived. Overall survival was higher in patients with MRD <0.1%. The prognosis was better in patients with AML-M3. Copyright © 2016 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.
Impact ionisation rate calculations in wide band gap semiconductors
International Nuclear Information System (INIS)
Harrison, D.
1998-09-01
Calculations of band-to-band impact ionisation rates performed in the semi-classical Fermi's Golden Rule approximation are presented here for the semiconductors GaAs, In 0.53 Ga 0.47 As and Si 0.5 Ge 0.5 at 300K. The crystal band structure is calculated using the empirical pseudopotential method. To increase the speed with which band structure data at arbitrary k-vectors can be obtained, an interpolation scheme has been developed. Energies are quadratically interpolated on adapted meshes designed to ensure accuracy is uniform throughout the Brillouin zone, and pseudowavefunctions are quadratically interpolated on a regular mesh. Matrix elements are calculated from the pseudowavefunctions, and include the terms commonly neglected in calculations for narrow band gap materials and an isotropic approximation to the full wavevector and frequency dependent dielectric function. The numerical integration of the rate over all distinct energy and wavevector conserving transitions is performed using two different algorithms. Results from each are compared and found to be in good agreement, indicating that the algorithms are reliable. The rates for electrons and holes in each material are calculated as functions of the k-vector of the impacting carriers, and found to be highly anisotropic. Average rates for impacting carriers at a given energy are calculated and fitted to Keldysh-type expressions with higher than quadratic dependence of the rate on energy above threshold being obtained in all cases. The average rates calculated here are compared to results obtained by other workers, with reasonable agreement being obtained for GaAs, and poorer agreement obtained for InGaAs and SiGe. Possible reasons for the disagreement are investigated. The impact ionisation thresholds are examined and k-space and energy distributions of generated carriers are determined. The role of threshold anisotropy, variation in the matrix elements and the shape of the bands in determining
The calculation of dose rates from rectangular sources
International Nuclear Information System (INIS)
Hartley, B.M.
1998-01-01
A common problem in radiation protection is the calculation of dose rates from extended sources and irregular shapes. Dose rates are proportional to the solid angle subtended by the source at the point of measurement. Simple methods of calculating solid angles would assist in estimating dose rates from large area sources and therefore improve predictive dose estimates when planning work near such sources. The estimation of dose rates is of particular interest to producers of radioactive ores but other users of bulk radioactive materials may have similar interest. The use of spherical trigonometry can assist in determination of solid angles and a simple equation is derived here for the determination of the dose at any distance from a rectangular surface. The solid angle subtended by complex shapes can be determined by modelling the area as a patchwork of rectangular areas and summing the solid angles from each rectangle. The dose rates from bags of thorium bearing ores is of particular interest in Western Australia and measured dose rates from bags and containers of monazite are compared with theoretical estimates based on calculations of solid angle. The agreement is fair but more detailed measurements would be needed to confirm the agreement with theory. (author)
SU-E-T-352: Why Is the Survival Rate Low in Oropharyngeal Squamous Cell Carcinoma?
Energy Technology Data Exchange (ETDEWEB)
Huang, Z; Feng, Y; Rasmussen, K; Rice, J; Stephenson, S; Ferreira, Maria C [East Carolina University, Greenville, NC (United States); Liu, T [Baylor College of Medicine, Houston, TX (United States); Yuh, K [California Institute of Technology, Pasadena, CA (United States); Wang, R; Grecula, J [Case Western Reserve University, Cleveland, OH (United States); Lo, S [The Ohio State University, Columbus, OH (United States); Mayr, N; Yuh, W [University of Washington, Seattle, WA (United States)
2014-06-01
Purpose: Tumors are composed of a large number of clonogens that have the capability of indefinite reproduction. Even when there is complete clinical or radiographic regression of the gross tumor mass after treatment, tumor recurrence can occur if the clonogens are not completely eradicated by radiotherapy. This study was to investigate the colonogen number and its association with the tumor control probability (TCP) in oropharyngeal squamous cell carcinoma (OSCCA). Methods: A literature search was conducted to collect clinical information of patients with OSCCA, including the prescription dose, tumor volume and survival rate. The linear-quadratic (LQ) model was incorporated into TCP model for clinical data analysis. The total dose ranged from 60 to 70 Gy and tumor volume ranged from 10 to 50 cc. The TCP was calculated for each group according to tumor size and dose. The least χ{sup 2} method was used to fit the TCP calculation to clinical data while other LQ model parameters (α, β) were adopted from the literature, due to the limited patient data. Results: A total of 190 patients with T2–T4 OSCCA were included. The association with HPV was not available for all the patients. The 3-year survival rate was about 82% for T2 squamous cell carcinoma and 40% for advanced tumors. Fitting the TCP model to the survival data, the average clonogen number was 1.56×10{sup 12}. For the prescription dose of 70 Gy, the calculated TCP ranged from 40% to 90% when the tumor volume varied from 10 to 50 cc. Conclusion: Our data suggests variation between the clonogen number and TCP in OSCCA. Tumors with larger colonogen number tend to have lower TCP and therefore dose escalation above 70 Gy may be indicated in order to improve the TCP and survival rate. Our result will require future confirmation with a large number of patients.
Effects of sample size on estimates of population growth rates calculated with matrix models.
Directory of Open Access Journals (Sweden)
Ian J Fiske
Full Text Available BACKGROUND: Matrix models are widely used to study the dynamics and demography of populations. An important but overlooked issue is how the number of individuals sampled influences estimates of the population growth rate (lambda calculated with matrix models. Even unbiased estimates of vital rates do not ensure unbiased estimates of lambda-Jensen's Inequality implies that even when the estimates of the vital rates are accurate, small sample sizes lead to biased estimates of lambda due to increased sampling variance. We investigated if sampling variability and the distribution of sampling effort among size classes lead to biases in estimates of lambda. METHODOLOGY/PRINCIPAL FINDINGS: Using data from a long-term field study of plant demography, we simulated the effects of sampling variance by drawing vital rates and calculating lambda for increasingly larger populations drawn from a total population of 3842 plants. We then compared these estimates of lambda with those based on the entire population and calculated the resulting bias. Finally, we conducted a review of the literature to determine the sample sizes typically used when parameterizing matrix models used to study plant demography. CONCLUSIONS/SIGNIFICANCE: We found significant bias at small sample sizes when survival was low (survival = 0.5, and that sampling with a more-realistic inverse J-shaped population structure exacerbated this bias. However our simulations also demonstrate that these biases rapidly become negligible with increasing sample sizes or as survival increases. For many of the sample sizes used in demographic studies, matrix models are probably robust to the biases resulting from sampling variance of vital rates. However, this conclusion may depend on the structure of populations or the distribution of sampling effort in ways that are unexplored. We suggest more intensive sampling of populations when individual survival is low and greater sampling of stages with high
Effects of sample size on estimates of population growth rates calculated with matrix models.
Fiske, Ian J; Bruna, Emilio M; Bolker, Benjamin M
2008-08-28
Matrix models are widely used to study the dynamics and demography of populations. An important but overlooked issue is how the number of individuals sampled influences estimates of the population growth rate (lambda) calculated with matrix models. Even unbiased estimates of vital rates do not ensure unbiased estimates of lambda-Jensen's Inequality implies that even when the estimates of the vital rates are accurate, small sample sizes lead to biased estimates of lambda due to increased sampling variance. We investigated if sampling variability and the distribution of sampling effort among size classes lead to biases in estimates of lambda. Using data from a long-term field study of plant demography, we simulated the effects of sampling variance by drawing vital rates and calculating lambda for increasingly larger populations drawn from a total population of 3842 plants. We then compared these estimates of lambda with those based on the entire population and calculated the resulting bias. Finally, we conducted a review of the literature to determine the sample sizes typically used when parameterizing matrix models used to study plant demography. We found significant bias at small sample sizes when survival was low (survival = 0.5), and that sampling with a more-realistic inverse J-shaped population structure exacerbated this bias. However our simulations also demonstrate that these biases rapidly become negligible with increasing sample sizes or as survival increases. For many of the sample sizes used in demographic studies, matrix models are probably robust to the biases resulting from sampling variance of vital rates. However, this conclusion may depend on the structure of populations or the distribution of sampling effort in ways that are unexplored. We suggest more intensive sampling of populations when individual survival is low and greater sampling of stages with high elasticities.
Calculation method for gamma dose rates from Gaussian puffs
Energy Technology Data Exchange (ETDEWEB)
Thykier-Nielsen, S; Deme, S; Lang, E
1995-06-01
The Lagrangian puff models are widely used for calculation of the dispersion of releases to the atmosphere. Basic output from such models is concentration of material in the air and on the ground. The most simple method for calculation of the gamma dose from the concentration of airborne activity is based on the semi-infinite cloud model. This method is however only applicable for puffs with large dispersion parameters, i.e. for receptors far away from the release point. The exact calculation of the cloud dose using volume integral requires large computer time usually exceeding what is available for real time calculations. The volume integral for gamma doses could be approximated by using the semi-infinite cloud model combined with correction factors. This type of calculation procedure is very fast, but usually the accuracy is poor because only a few of the relevant parameters are considered. A multi-parameter method for calculation of gamma doses is described here. This method uses precalculated values of the gamma dose rates as a function of E{sub {gamma}}, {sigma}{sub y}, the asymmetry factor - {sigma}{sub y}/{sigma}{sub z}, the height of puff center - H and the distance from puff center R{sub xy}. To accelerate the calculations the release energy, for each significant radionuclide in each energy group, has been calculated and tabulated. Based on the precalculated values and suitable interpolation procedure the calculation of gamma doses needs only short computing time and it is almost independent of the number of radionuclides considered. (au) 2 tabs., 15 ills., 12 refs.
Calculation method for gamma dose rates from Gaussian puffs
International Nuclear Information System (INIS)
Thykier-Nielsen, S.; Deme, S.; Lang, E.
1995-06-01
The Lagrangian puff models are widely used for calculation of the dispersion of releases to the atmosphere. Basic output from such models is concentration of material in the air and on the ground. The most simple method for calculation of the gamma dose from the concentration of airborne activity is based on the semi-infinite cloud model. This method is however only applicable for puffs with large dispersion parameters, i.e. for receptors far away from the release point. The exact calculation of the cloud dose using volume integral requires large computer time usually exceeding what is available for real time calculations. The volume integral for gamma doses could be approximated by using the semi-infinite cloud model combined with correction factors. This type of calculation procedure is very fast, but usually the accuracy is poor because only a few of the relevant parameters are considered. A multi-parameter method for calculation of gamma doses is described here. This method uses precalculated values of the gamma dose rates as a function of E γ , σ y , the asymmetry factor - σ y /σ z , the height of puff center - H and the distance from puff center R xy . To accelerate the calculations the release energy, for each significant radionuclide in each energy group, has been calculated and tabulated. Based on the precalculated values and suitable interpolation procedure the calculation of gamma doses needs only short computing time and it is almost independent of the number of radionuclides considered. (au) 2 tabs., 15 ills., 12 refs
RCS Leak Rate Calculation with High Order Least Squares Method
International Nuclear Information System (INIS)
Lee, Jeong Hun; Kang, Young Kyu; Kim, Yang Ki
2010-01-01
As a part of action items for Application of Leak before Break(LBB), RCS Leak Rate Calculation Program is upgraded in Kori unit 3 and 4. For real time monitoring of operators, periodic calculation is needed and corresponding noise reduction scheme is used. This kind of study was issued in Korea, so there have upgraded and used real time RCS Leak Rate Calculation Program in UCN unit 3 and 4 and YGN unit 1 and 2. For reduction of the noise in signals, Linear Regression Method was used in those programs. Linear Regression Method is powerful method for noise reduction. But the system is not static with some alternative flow paths and this makes mixed trend patterns of input signal values. In this condition, the trend of signal and average of Linear Regression are not entirely same pattern. In this study, high order Least squares Method is used to follow the trend of signal and the order of calculation is rearranged. The result of calculation makes reasonable trend and the procedure is physically consistence
Calculation method for gamma-dose rates from spherical puffs
International Nuclear Information System (INIS)
Thykier-Nielsen, S.; Deme, S.; Lang, E.
1993-05-01
The Lagrangian puff-models are widely used for calculation of the dispersion of atmospheric releases. Basic output from such models are concentrations of material in the air and on the ground. The most simple method for calculation of the gamma dose from the concentration of airborne activity is based on semi-infinite cloud model. This method is however only applicable for points far away from the release point. The exact calculation of the cloud dose using the volume integral requires significant computer time. The volume integral for the gamma dose could be approximated by using the semi-infinite cloud model combined with correction factors. This type of calculation procedure is very fast, but usually the accuracy is poor due to the fact that the same correction factors are used for all isotopes. The authors describe a more elaborate correction method. This method uses precalculated values of the gamma-dose rate as a function of the puff dispersion parameter (δ p ) and the distance from the puff centre for four energy groups. The release of energy for each radionuclide in each energy group has been calculated and tabulated. Based on these tables and a suitable interpolation procedure the calculation of gamma doses takes very short time and is almost independent of the number of radionuclides. (au) (7 tabs., 7 ills., 12 refs.)
A Kidney Graft Survival Calculator that Accounts for Mismatches in Age, Sex, HLA, and Body Size.
Ashby, Valarie B; Leichtman, Alan B; Rees, Michael A; Song, Peter X-K; Bray, Mathieu; Wang, Wen; Kalbfleisch, John D
2017-07-07
Outcomes for transplants from living unrelated donors are of particular interest in kidney paired donation (KPD) programs where exchanges can be arranged between incompatible donor-recipient pairs or chains created from nondirected/altruistic donors. Using Scientific Registry of Transplant Recipients data, we analyzed 232,705 recipients of kidney-alone transplants from 1998 to 2012. Graft failure rates were estimated using Cox models for recipients of kidney transplants from living unrelated, living related, and deceased donors. Models were adjusted for year of transplant and donor and recipient characteristics, with particular attention to mismatches in age, sex, human leukocyte antigens (HLA), body size, and weight. The dependence of graft failure on increasing donor age was less pronounced for living-donor than for deceased-donor transplants. Male donor-to-male recipient transplants had lower graft failure, particularly better than female to male (5%-13% lower risk). HLA mismatch was important in all donor types. Obesity of both the recipient (8%-18% higher risk) and donor (5%-11% higher risk) was associated with higher graft loss, as were donor-recipient weight ratios of transplants where both parties were of similar weight (9%-12% higher risk). These models are used to create a calculator of estimated graft survival for living donors. This calculator provides useful information to donors, candidates, and physicians of estimated outcomes and potentially in allowing candidates to choose among several living donors. It may also help inform candidates with compatible donors on the advisability of joining a KPD program. Copyright © 2017 by the American Society of Nephrology.
Outcomes of chronic dialysis in Korean children with respect to survival rates and causes of death
Chang, Hye Jin; Han, Kyoung Hee; Cho, Min Hyun; Park, Young Seo; Kang, Hee Gyung; Cheong, Hae Il; Ha, Il Soo
2014-01-01
Purpose Adult Korean patients on chronic dialysis have a 9-year survival rate of 50%, with cardiovascular problems being the most significant cause of death. The 2011 annual report of the North American Pediatric Renal Trials and Collaborative Studies group reported 3-year survival rates of 93.4% and relatively poorer survival in younger patients. Methods In this study, we have reviewed data from Korean Pediatric Chronic Kidney Disease Registry from 2002 to 2010 to assess survival rates and c...
Semiclassical Calculation of Reaction Rate Constants for Homolytical Dissociations
Cardelino, Beatriz H.
2002-01-01
There is growing interest in extending organometallic chemical vapor deposition (OMCVD) to III-V materials that exhibit large thermal decomposition at their optimum growth temperature, such as indium nitride. The group III nitrides are candidate materials for light-emitting diodes and semiconductor lasers operating into the blue and ultraviolet regions. To overcome decomposition of the deposited compound, the reaction must be conducted at high pressures, which causes problems of uniformity. Microgravity may provide the venue for maintaining conditions of laminar flow under high pressure. Since the selection of optimized parameters becomes crucial when performing experiments in microgravity, efforts are presently geared to the development of computational OMCVD models that will couple the reactor fluid dynamics with its chemical kinetics. In the present study, we developed a method to calculate reaction rate constants for the homolytic dissociation of III-V compounds for modeling OMCVD. The method is validated by comparing calculations with experimental reaction rate constants.
A New Method to Calculate Internal Rate of Return
Directory of Open Access Journals (Sweden)
azadeh zandi
2015-09-01
Full Text Available A number of methods have been developed to choose the best capital investment projects such as net present value, internal rate of return and etc. Internal rate of return method is probably the most popular method among managers and investors. But despite the popularity there are serious drawbacks and limitations in this method. After decades of efforts made by economists and experts to improve the method and its shortcomings, Magni in 2010 has revealed a new approach that can solves the most of internal rate of return method problems. This paper present a new method which is originated from Magni’s approach but has much more simple calculations and can resolve all the drawbacks of internal rate of return method.
Survival rate of eukaryotic cells following electrophoretic nanoinjection.
Simonis, Matthias; Hübner, Wolfgang; Wilking, Alice; Huser, Thomas; Hennig, Simon
2017-01-25
Insertion of foreign molecules such as functionalized fluorescent probes, antibodies, or plasmid DNA to living cells requires overcoming the plasma membrane barrier without harming the cell during the staining process. Many techniques such as electroporation, lipofection or microinjection have been developed to overcome the cellular plasma membrane, but they all result in reduced cell viability. A novel approach is the injection of cells with a nanopipette and using electrophoretic forces for the delivery of molecules. The tip size of these pipettes is approximately ten times smaller than typical microinjection pipettes and rather than pressure pulses as delivery method, moderate DC electric fields are used to drive charged molecules out of the tip. Here, we show that this approach leads to a significantly higher survival rate of nanoinjected cells and that injection with nanopipettes has a significantly lower impact on the proliferation behavior of injected cells. Thus, we propose that injection with nanopipettes using electrophoretic delivery is an excellent alternative when working with valuable and rare living cells, such as primary cells or stem cells.
Survival rate of eukaryotic cells following electrophoretic nanoinjection
Simonis, Matthias; Hübner, Wolfgang; Wilking, Alice; Huser, Thomas; Hennig, Simon
2017-01-01
Insertion of foreign molecules such as functionalized fluorescent probes, antibodies, or plasmid DNA to living cells requires overcoming the plasma membrane barrier without harming the cell during the staining process. Many techniques such as electroporation, lipofection or microinjection have been developed to overcome the cellular plasma membrane, but they all result in reduced cell viability. A novel approach is the injection of cells with a nanopipette and using electrophoretic forces for the delivery of molecules. The tip size of these pipettes is approximately ten times smaller than typical microinjection pipettes and rather than pressure pulses as delivery method, moderate DC electric fields are used to drive charged molecules out of the tip. Here, we show that this approach leads to a significantly higher survival rate of nanoinjected cells and that injection with nanopipettes has a significantly lower impact on the proliferation behavior of injected cells. Thus, we propose that injection with nanopipettes using electrophoretic delivery is an excellent alternative when working with valuable and rare living cells, such as primary cells or stem cells. PMID:28120926
Empirical rate equation model and rate calculations of hydrogen generation for Hanford tank waste
International Nuclear Information System (INIS)
HU, T.A.
1999-01-01
Empirical rate equations are derived to estimate hydrogen generation based on chemical reactions, radiolysis of water and organic compounds, and corrosion processes. A comparison of the generation rates observed in the field with the rates calculated for twenty eight tanks shows agreement within a factor of two to three
NAC-1 cask dose rate calculations for LWR spent fuel
International Nuclear Information System (INIS)
CARLSON, A.B.
1999-01-01
A Nuclear Assurance Corporation nuclear fuel transport cask, NAC-1, is being considered as a transport and storage option for spent nuclear fuel located in the B-Cell of the 324 Building. The loaded casks will be shipped to the 200 East Area Interim Storage Area for dry interim storage. Several calculations were performed to assess the photon and neutron dose rates. This report describes the analytical methods, models, and results of this investigation
Divided Saddle Theory: A New Idea for Rate Constant Calculation.
Daru, János; Stirling, András
2014-03-11
We present a theory of rare events and derive an algorithm to obtain rates from postprocessing the numerical data of a free energy calculation and the corresponding committor analysis. The formalism is based on the division of the saddle region of the free energy profile of the rare event into two adjacent segments called saddle domains. The method is built on sampling the dynamics within these regions: auxiliary rate constants are defined for the saddle domains and the absolute forward and backward rates are obtained by proper reweighting. We call our approach divided saddle theory (DST). An important advantage of our approach is that it requires only standard computational techniques which are available in most molecular dynamics codes. We demonstrate the potential of DST numerically on two examples: rearrangement of alanine-dipeptide (CH3CO-Ala-NHCH3) conformers and the intramolecular Cope reaction of the fluxional barbaralane molecule.
Comparison between calculation methods of dose rates in gynecologic brachytherapy
International Nuclear Information System (INIS)
Vianello, E.A.; Biaggio, M.F.; D R, M.F.; Almeida, C.E. de
1998-01-01
In treatments with radiations for gynecologic tumors is necessary to evaluate the quality of the results obtained by different calculation methods for the dose rates on the points of clinical interest (A, rectal, vesicle). The present work compares the results obtained by two methods. The Manual Calibration Method (MCM) tri dimensional (Vianello E., et.al. 1998), using orthogonal radiographs for each patient in treatment, and the Theraplan/T P-11 planning system (Thratonics International Limited 1990) this last one verified experimentally (Vianello et.al. 1996). The results show that MCM can be used in the physical-clinical practice with a percentile difference comparable at the computerized programs. (Author)
X particle effect for 6Li reaction rates calculations
International Nuclear Information System (INIS)
Kocak, G.; Balantekin, A. B.
2009-01-01
The inferred primordial 6 L i-7 L i abundances are different from standard big bang nucleosynthesis results, 6 L i is 1000 times larger and 7 L i is 3 times smaller than the big bang prediction. In big bang nucleosynthesis, negatively charged massive X particles a possible solution to explain this primordial Li abundances problem [1]. In this study, we consider only X particle effect for nuclear reactions to obtain S-factor and reaction rates for Li. All S-factors calculated within the Optical Model framework for d(α,γ)6 L i system. We showed that the enhancement effect of massive negatively charged X particle for 6 L i system reaction rate.(author)
The validity of EORTC GBM prognostic calculator on survival of GBM patients in the West of Scotland.
Teo, Mario; Clark, Brian; MacKinnon, Mairi; Stewart, Willie; Paul, James; St George, Jerome
2014-06-01
It is now accepted that the addition of temozolomide to radiotherapy in the treatment of patients with newly diagnosed glioblastoma multiforme (GBM) significantly improves survival. In 2008, a subanalysis of the original study data was performed, and an online "GBM Calculator" was made available on the European Organisation for Research and Treatment of Cancer (EORTC) website allowing users to estimate patients' survival outcomes. We tested this calculator against actual local survival data to validate its use in our patients. Prospectively collected clinical data were analysed on 105 consecutive patients receiving concurrent chemoradiotherapy following surgical treatment of GBM between December 2004 and February 2009. Using the EORTC online calculator, survival outcomes were generated for these patients and compared with their actual survival. The median overall survival for the entire cohort was 15.3 months (range 2.8-50.5 months), with 1-year and 2-year overall survival of 65.7% and 19%, respectively. This is in comparison to the median overall predictive survival of 21.3 months, with 1-year and 2-year survival of 95% and 39.5%, respectively. Case by case analysis also showed that the survival was overestimated in nearly 80% of patients. Subgroup analyses showed similar overestimation of patients' survival, except calculator Model 3 which utilised MGMT status. Use of the EORTC GBM prognostic calculator would have overestimated the survival of the majority of our patients with GBM. Uncertainty exists as to the cause of overestimation in the cohort although local socioeconomic factors might play a role. The different calculator models yielded different outcomes and the "best" predictor of survival for the cohort under study utilised the tumour MGMT status. We would strongly encourage similar local studies of validity testing prior to employing the online prognostic calculator for other population groups.
Benchmark calculations for evaluation methods of gas volumetric leakage rate
International Nuclear Information System (INIS)
Asano, R.; Aritomi, M.; Matsuzaki, M.
1998-01-01
A containment function of radioactive materials transport casks is essential for safe transportation to prevent the radioactive materials from being released into environment. Regulations such as IAEA standard determined the limit of radioactivity to be released. Since is not practical for the leakage tests to measure directly the radioactivity release from a package, as gas volumetric leakages rates are proposed in ANSI N14.5 and ISO standards. In our previous works, gas volumetric leakage rates for several kinds of gas from various leaks were measured and two evaluation methods, 'a simple evaluation method' and 'a strict evaluation method', were proposed based on the results. The simple evaluation method considers the friction loss of laminar flow with expansion effect. The strict evaluating method considers an exit loss in addition to the friction loss. In this study, four worked examples were completed for on assumed large spent fuel transport cask (Type B Package) with wet or dry capacity and at three transport conditions; normal transport with intact fuels or failed fuels, and an accident in transport. The standard leakage rates and criteria for two kinds of leak test were calculated for each example by each evaluation method. The following observations are made based upon the calculations and evaluations: the choked flow model of ANSI method greatly overestimates the criteria for tests ; the laminar flow models of both ANSI and ISO methods slightly overestimate the criteria for tests; the above two results are within the design margin for ordinary transport condition and all methods are useful for the evaluation; for severe condition such as failed fuel transportation, it should pay attention to apply a choked flow model of ANSI method. (authors)
Directory of Open Access Journals (Sweden)
Rafael Maciel-de-Freitas
2008-12-01
Full Text Available Population size and daily survival rates of disease vectors are important determinants of vectorial capacity. A mark-release-recapture experiment was conducted in a dengue endemic urban neighborhood of Rio de Janeiro, Brazil, to estimate population size, survival rate and vectorial capacity of Aedes aegypti females using back-pack aspirators and gravid sticky traps (MosquiTRAP. Estimations of the gravid female population size were different when using data gathered from just the MosquiTRAP (3,505 individuals or aspirator (1,470. However Ae. aegypti survival rates and longevity were similar irrespective of the method of capture. Up to 26.3% of released females would be able to survive for more than 10 days, the length of time of the extrinsic incubation period. Vectorial capacity value ranged between 0.01567 and 0.4215 and the basic reproductive number (R0 was estimated to be between 0.0695 and 1.88.O tamanho populacional e a taxa de sobrevivência de vetores de doenças são importantes componentes da capacidade vetorial. Um experimento de marcação-soltura-recaptura foi conduzido numa área urbana endêmica de dengue no Rio de Janeiro, Brasil, para estimar o tamanho populacional, taxa de sobrevivência diária e capacidade vetorial de fêmeas de Aedes aegypti; para tal, usaram-se aspirador costal e armadilha para fêmeas grávidas de Ae. aegypti (MosquiTRAP. Estimativas do tamanho populacional de fêmeas grávidas foram diferentes quando foram analisados dados coletados apenas na MosquiTRAP (3.505 indivíduos e aspiradores (1.470. Por outro lado, taxas de sobrevivência e longevidade de Ae. aegypti foram semelhantes independentemente do método de captura empregado. Até 26,3% das fêmeas seriam capazes de sobreviver mais do que dez dias, tempo equivalente à duração do período de incubação extrínseco. O cálculo da capacidade vetorial revelou valores entre 0,01567 e 0,4215, e o número básico de reprodução foi estimado entre 0,0695 e
Approaches to proton single-event rate calculations
International Nuclear Information System (INIS)
Petersen, E.L.
1996-01-01
This article discusses the fundamentals of proton-induced single-event upsets and of the various methods that have been developed to calculate upset rates. Two types of approaches are used based on nuclear-reaction analysis. Several aspects can be analyzed using analytic methods, but a complete description is not available. The paper presents an analytic description for the component due to elastic-scattering recoils. There have been a number of studies made using Monte Carlo methods. These can completely describe the reaction processes, including the effect of nuclear reactions occurring outside the device-sensitive volume. They have not included the elastic-scattering processes. The article describes the semiempirical approaches that are most widely used. The quality of previous upset predictions relative to space observations is discussed and leads to comments about the desired quality of future predictions. Brief sections treat the possible testing limitation due to total ionizing dose effects, the relationship of proton and heavy-ion upsets, upsets due to direct proton ionization, and relative proton and cosmic-ray upset rates
Survival and mortality rates among Danes with MS
DEFF Research Database (Denmark)
Brønnum-Hansen, H; Stenager, Egon; Hansen, Thomas
2006-01-01
Long-term survival and trends in overall and cause-specific excess mortality among people with MS have been studied using the Danish Multiple Sclerosis Registry, which contains information about all Danish MS patients since the mid-20th Century. A total of 4254 deaths among approximately 10......,000 people with MS, representing more than 200,000 person-years of observation, have been analysed. Overall, mortality was almost three times higher and life expectancy 10 years less among people with MS than for the general population. However, excess mortality has declined significantly since 1950....
[Survival rate of IPS-Empress 2 all-ceramic crowns and bridges: three year's results].
Zimmer, Doris; Gerds, Thomas; Strub, Jörg R
2004-01-01
The objective of this prospective clinical study was to calculate the survival rate of IPS-Empress2 crowns and fixed partial dentures (FPD) over a three-year period. In 43 patients 27 IPS-Empress2 crowns and 31 fixed partial dentures were adhesively luted. Crowns were placed on premolars and molars and FPDs were inserted in the anterior and premolar area. Abutments were prepared with a circular 1.2 mm wide shoulder. The clinical follow-up examination took place after 6, 12, 24, 36 and 48 months. After a mean of 38 months, the survival rate (Kaplan-Meier) of all-ceramic crowns was 100% and of the three unit FDP 72.4%. There were a total of six complete failures which occurred only with the three-unit IPS-Empress2 FPDs. Three FPDs exhibited fractures of the framework for which the manufacturer's instructions of connector-dimension was not satisfied, and one FPD exhibited an irreparable incomplete veneer fracture. Further two FPDs showed biological failures. The accuracy of fit and esthetics were clinically satisfactory. The three-year results showed the IPS-Empress2-ceramic as an adequate all-ceramic material for single crowns. The use for FPD needs further critical consideration.
Variationally Optimized Free-Energy Flooding for Rate Calculation
McCarty, James; Valsson, Omar; Tiwary, Pratyush; Parrinello, Michele
2015-08-01
We propose a new method to obtain kinetic properties of infrequent events from molecular dynamics simulation. The procedure employs a recently introduced variational approach [Valsson and Parrinello, Phys. Rev. Lett. 113, 090601 (2014)] to construct a bias potential as a function of several collective variables that is designed to flood the associated free energy surface up to a predefined level. The resulting bias potential effectively accelerates transitions between metastable free energy minima while ensuring bias-free transition states, thus allowing accurate kinetic rates to be obtained. We test the method on a few illustrative systems for which we obtain an order of magnitude improvement in efficiency relative to previous approaches and several orders of magnitude relative to unbiased molecular dynamics. We expect an even larger improvement in more complex systems. This and the ability of the variational approach to deal efficiently with a large number of collective variables will greatly enhance the scope of these calculations. This work is a vindication of the potential that the variational principle has if applied in innovative ways.
Variability in nest survival rates and implications to nesting studies
Klett, A.T.; Johnson, D.H.
1982-01-01
We used four reasonably large samples (83-213) of Mallard (Anas platyrhynchos) and Blue-winged Teal (A. discors) nests on an interstate highway right-of-way in southcentral North Dakota to evaluate potential biases in hatch-rate estimates. Twelve consecutive, weekly searches for nests were conducted with a cable-chain drag in 1976 and 1977. Nests were revisited at weekly intervals. Four methods were used to estimate hatch rates for the four data sets: the Traditional Method, the Mayfield Method, and two modifications of the Mayfield Method that are sometimes appropriate when daily mortality rates of nests are not constant. Hatch rates and the average age of nests at discovery declined as the interval between searches decreased, suggesting that mortality rates were not constant in our samples. An analysis of variance indicated that daily mortality rates varied with the age of nests in all four samples. Mortality was generally highest during the early laying period, moderately high during the late laying period, and lowest during incubation. We speculate that this relationship of mortality to nest age might be due to the presence of hens at nests or to differences in the vulnerability of nest sites to predation. A modification of the Mayfield Method that accounts for age-related variation in nest mortality was most appropriate for our samples. We suggest methods for conducting nesting studies and estimating nest success for species possessing similar nesting habits.
Stathopoulos, Panagiotis; Smith, William P
2017-06-01
The aim of this study is to present the survival rates in patients treated for oral cancer with primary surgery in a large district general hospital. We discuss the influence of the most significant prognostic factors on survival and compare our results with larger centres specializing in the management of oral cancer. All patients diagnosed with oral cancer from 1995 to 2006 and were treated in the Department had their details entered prospectively onto a computerized database. Demographic details of patients, type of treatment, pathological stage of tumor (TNM), local and regional recurrence rate, overall survival, disease specific survival and incidence of involved margins were recorded and calculated. Of the 178 patients, 96 (54 %) were alive and free of oral cancer 5 years after surgery. Forty-four patients died of oral cancer (24.7 %) but 38 (21.3 %) died of other causes. The overall survival rate after primary surgery in relation to stage was: I 84 %, II 71 %, III 36 % and IV 28 %. As almost half of our patients presented with advanced cancer and had discouraging survival rates, we emphasize the need for early recognition of the disease. Advanced disease signifies difficulty in obtaining clear margins which actually indicates a higher recurrence rate. 25 % of our patients died of oral cancer within 5 years of surgery which highlights the poor prognosis that recurrence carries after treatment. Effective educational campaign with purpose to raise oral cancer awareness and earlier referral may result in improvement of survival.
One year Survival Rate of Ketac Molar versus Vitro Molar for Occlusoproximal ART Restorations: a RCT
Directory of Open Access Journals (Sweden)
PACHECO Anna Luisa de Brito
2017-11-01
Full Text Available Abstract Good survival rates for single-surface Atraumatic Restorative Treatment (ART restorations have been reported, while multi-surface ART restorations have not shown similar results. The aim of this study was to evaluate the survival rate of occluso-proximal ART restorations using two different filling materials: Ketac Molar EasyMix (3M ESPE and Vitro Molar (DFL. A total of 117 primary molars with occluso-proximal caries lesions were selected in 4 to 8 years old children in Barueri city, Brazil. Only one tooth was selected per child. The subjetcs were randomly allocated in two groups according to the filling material. All treatments were performed following the ART premises and all restorations were evaluated after 2, 6 and 12 months. Restoration survival was evaluated using Kaplan-Meier survival analysis and Log-rank test, while Cox regression analysis was used for testing association with clinical factors (α = 5%. There was no difference in survival rate between the materials tested, (HR = 1.60, CI = 0.98–2.62, p = 0.058. The overall survival rate of restorations was 42.74% and the survival rate per group was Ketac Molar = 50,8% and Vitro Molar G2 = 34.5%. Cox regression test showed no association between the analyzed clinical variables and the success of the restorations. After 12 months evaluation, no difference in the survival rate of ART occluso-proximal restorations was found between tested materials.
Is the rate of metabolic ageing and survival determined by Basal metabolic rate in the zebra finch?
Directory of Open Access Journals (Sweden)
Bernt Rønning
Full Text Available The relationship between energy metabolism and ageing is of great interest because aerobic metabolism is the primary source of reactive oxygen species which is believed to be of major importance in the ageing process. We conducted a longitudinal study on captive zebra finches where we tested the effect of age on basal metabolic rate (BMR, as well as the effect of BMR on the rate of metabolic ageing (decline in BMR with age and survival. Basal metabolic rate declined with age in both sexes after controlling for the effect of body mass, indicating a loss of functionality with age. This loss of functionality could be due to accumulated oxidative damage, believed to increase with increasing metabolic rate, c.f. the free radical theory of ageing. If so, we would expect the rate of metabolic ageing to increase and survival to decrease with increasing BMR. However, we found no effect of BMR on the rate of metabolic ageing. Furthermore, survival was not affected by BMR in the males. In female zebra finches there was a tendency for survival to decrease with increasing BMR, but the effect did not reach significance (P<0.1. Thus, the effect of BMR on the rate of functional deterioration with age, if any, was not strong enough to influence neither the rate of metabolic ageing nor survival in the zebra finches.
Is the rate of metabolic ageing and survival determined by Basal metabolic rate in the zebra finch?
Rønning, Bernt; Moe, Børge; Berntsen, Henrik H; Noreen, Elin; Bech, Claus
2014-01-01
The relationship between energy metabolism and ageing is of great interest because aerobic metabolism is the primary source of reactive oxygen species which is believed to be of major importance in the ageing process. We conducted a longitudinal study on captive zebra finches where we tested the effect of age on basal metabolic rate (BMR), as well as the effect of BMR on the rate of metabolic ageing (decline in BMR with age) and survival. Basal metabolic rate declined with age in both sexes after controlling for the effect of body mass, indicating a loss of functionality with age. This loss of functionality could be due to accumulated oxidative damage, believed to increase with increasing metabolic rate, c.f. the free radical theory of ageing. If so, we would expect the rate of metabolic ageing to increase and survival to decrease with increasing BMR. However, we found no effect of BMR on the rate of metabolic ageing. Furthermore, survival was not affected by BMR in the males. In female zebra finches there was a tendency for survival to decrease with increasing BMR, but the effect did not reach significance (PBMR on the rate of functional deterioration with age, if any, was not strong enough to influence neither the rate of metabolic ageing nor survival in the zebra finches.
Controls on Arctic sea ice from first-year and multi-year ice survival rates
Armour, K.; Bitz, C. M.; Hunke, E. C.; Thompson, L.
2009-12-01
The recent decrease in Arctic sea ice cover has transpired with a significant loss of multi-year (MY) ice. The transition to an Arctic that is populated by thinner first-year (FY) sea ice has important implications for future trends in area and volume. We develop a reduced model for Arctic sea ice with which we investigate how the survivability of FY and MY ice control various aspects of the sea-ice system. We demonstrate that Arctic sea-ice area and volume behave approximately as first-order autoregressive processes, which allows for a simple interpretation of September sea-ice in which its mean state, variability, and sensitivity to climate forcing can be described naturally in terms of the average survival rates of FY and MY ice. This model, used in concert with a sea-ice simulation that traces FY and MY ice areas to estimate the survival rates, reveals that small trends in the ice survival rates explain the decline in total Arctic ice area, and the relatively larger loss of MY ice area, over the period 1979-2006. Additionally, our model allows for a calculation of the persistence time scales of September area and volume anomalies. A relatively short memory time scale for ice area (~ 1 year) implies that Arctic ice area is nearly in equilibrium with long-term climate forcing at all times, and therefore observed trends in area are a clear indication of a changing climate. A longer memory time scale for ice volume (~ 5 years) suggests that volume can be out of equilibrium with climate forcing for long periods of time, and therefore trends in ice volume are difficult to distinguish from its natural variability. With our reduced model, we demonstrate the connection between memory time scale and sensitivity to climate forcing, and discuss the implications that a changing memory time scale has on the trajectory of ice area and volume in a warming climate. Our findings indicate that it is unlikely that a “tipping point” in September ice area and volume will be
Modeling the effect of temperature on survival rate of Salmonella Enteritidis in yogurt.
Szczawiński, J; Szczawińska, M E; Łobacz, A; Jackowska-Tracz, A
2014-01-01
The aim of the study was to determine the inactivation rates of Salmonella Enteritidis in commercially produced yogurt and to generate primary and secondary mathematical models to predict the behaviour of these bacteria during storage at different temperatures. The samples were inoculated with the mixture of three S. Enteritidis strains and stored at 5 degrees C, 10 degrees C, 15 degrees C, 20 degrees C and 25 degrees C for 24 h. The number of salmonellae was determined every two hours. It was found that the number of bacteria decreased linearly with storage time in all samples. Storage temperature and pH of yogurt significantly influenced survival rate of S. Enteritidis (p bacteria was the most dynamic. The natural logarithm of mean inactivation rates of Salmonella calculated from primary model was fitted to two secondary models: linear and polynomial. Equations obtained from both secondary models can be applied as a tool for prediction of inactivation rate of Salmonella in yogurt stored under temperature range from 5 to 25 degrees C; however, polynomial model gave the better fit to the experimental data.
Jung, Min Hee; Oh, Je Hyeok; Kim, Chan Woong; Kim, Sung Eun; Lee, Dong Hoon; Chang, Wen Joen
2015-08-01
We investigated whether visual feedback from an accelerometer device facilitated high-quality chest compressions during an in-hospital cardiac arrest simulation using a manikin. Thirty health care providers participated in an in-hospital cardiac arrest simulation with 1 minute of continuous chest compressions. Chest compressions were performed on a manikin lying on a bed according to visual feedback from an accelerometer feedback device. The manikin and accelerometer recorded chest compression data simultaneously. The simulated patient was deemed to have survived when the chest compression data satisfied all of the preset high-quality chest compression criteria (depth ≥51 mm, rate >100 per minute, and ≥95% full recoil). Survival rates were calculated from the feedback device and manikin data. The survival rate according to the feedback device data was 80%; however, the manikin data indicated a significantly lower survival rate (46.7%; P = .015). The difference between the accelerometer and manikin survival rates was not significant for participants with a body mass index greater than or equal to 20 kg/m(2) (93.3 vs 73.3%, respectively; P = .330); however, the difference in survival rate was significant in participants with body mass index less than 20 kg/m(2) (66.7 vs 20.0%, respectively; P = .025). The use of accelerometer feedback devices to facilitate high-quality chest compression may not be appropriate for lightweight rescuers because of the potential for compression depth overestimation. Clinical Research Information Service (KCT0001449). Copyright © 2015 Elsevier Inc. All rights reserved.
SURVIVAL RATES IN ORAL CANCER PATIENTS – A 10-YEAR RETROSPECTIVE STUDY
Directory of Open Access Journals (Sweden)
Konstantin Tonchev
2016-12-01
Full Text Available Oral cancer is the eighth most common cancer worldwide and presents a serious health problem in countries with higher alcohol consumption and smoking. The aim of the present study was to analyze the survival rates of patients with oral cancer diagnosed at a single center in Bulgaria. The clinical records of patients with oral cancer admitted to the Clinic of Maxillofacial surgery, University Hospital “St. George”, Plovdiv, Bulgaria, from 2004 till 2013 were reviewed. Additional information about follow-up was obtained from the Regional Complex Oncological Centre (RCOC. Data about patient and tumor characteristics – age, sex, site of cancer, stage, degree of differentiation and survival rates were analyzed. The overall 5-year survival rate was 36% while the disease-specific survival rate was 45%. The highest chance for survival was for upper lip (66% while the lowest was for retromolar trigone (0%. Overall survival rate depended also on the stage and grade of differentiation of the tumor. The study confirmed that oral cancer remains serious problem in terms of risk factors, delayed diagnosis, and overall survival rates.
Current evaluation of dose rate calculation - analytical method
International Nuclear Information System (INIS)
Tello, Marcos; Vilhena, Marco Tulio
1996-01-01
The accuracy of the dose calculations based on pencil beam formulas such as Fokker-Plank equations and Fermi equations for charged particle transport are studied and a methodology to solve the Boltzmann transport equation is suggested
Calculation of the decay rate of the proton
International Nuclear Information System (INIS)
Ross, D.A.
1980-01-01
The SU(5) model of Georgi and Glashow is used for these calculations, being the simplist such model and since the point of unification of the strong, weak and electromagnetic interactions is very intensitive to the exact details of the model provided it obeys the desert hypothesis. The broad features of the calculation are common to all models with a dessert between the W-mass and unification
Estimation of survival rates and abundance of green turtles along the U.S. West Coast
National Oceanic and Atmospheric Administration, Department of Commerce — To determine abundance and survival rates of the east Pacific green turtles in the northern most foraging grounds, the turtle research groups at SWFSC have been...
Seasonal survival rates and causes of mortality of Little Owls in Denmark
DEFF Research Database (Denmark)
Thorup, Kasper; Pedersen, Dorthe; Sunde, Peter
2013-01-01
Survival rate is an essential component of population dynamics; therefore, identification of variation in mortality rates and the factors that influence them might be of key importance in understanding why populations increase or decrease. In Denmark, the Little Owl Athene noctua, a species...... the causes of current survival rates, we estimated age- and season-specific survival rates and causes of mortality in Danish Little Owls on the basis of ringed birds 1920–2002, radio tagged adult and juveniles 2005–2008 and nest surveys 2006–2008. We estimate that 32 % of all eggs fledge and survive to 2...... the breeding season. In radio-tagged adults and fledged juveniles, accidents in buildings and other human infrastructures were responsible for two-thirds of all fatalities. Anthropogenic habitats currently comprise the nesting and roosting habitats for the last Danish Little Owls. The accidental deaths...
Survival behavior in the cyclic Lotka-Volterra model with a randomly switching reaction rate
West, Robert; Mobilia, Mauro; Rucklidge, Alastair M.
2018-02-01
We study the influence of a randomly switching reproduction-predation rate on the survival behavior of the nonspatial cyclic Lotka-Volterra model, also known as the zero-sum rock-paper-scissors game, used to metaphorically describe the cyclic competition between three species. In large and finite populations, demographic fluctuations (internal noise) drive two species to extinction in a finite time, while the species with the smallest reproduction-predation rate is the most likely to be the surviving one (law of the weakest). Here we model environmental (external) noise by assuming that the reproduction-predation rate of the strongest species (the fastest to reproduce and predate) in a given static environment randomly switches between two values corresponding to more and less favorable external conditions. We study the joint effect of environmental and demographic noise on the species survival probabilities and on the mean extinction time. In particular, we investigate whether the survival probabilities follow the law of the weakest and analyze their dependence on the external noise intensity and switching rate. Remarkably, when, on average, there is a finite number of switches prior to extinction, the survival probability of the predator of the species whose reaction rate switches typically varies nonmonotonically with the external noise intensity (with optimal survival about a critical noise strength). We also outline the relationship with the case where all reaction rates switch on markedly different time scales.
Survival behavior in the cyclic Lotka-Volterra model with a randomly switching reaction rate.
West, Robert; Mobilia, Mauro; Rucklidge, Alastair M
2018-02-01
We study the influence of a randomly switching reproduction-predation rate on the survival behavior of the nonspatial cyclic Lotka-Volterra model, also known as the zero-sum rock-paper-scissors game, used to metaphorically describe the cyclic competition between three species. In large and finite populations, demographic fluctuations (internal noise) drive two species to extinction in a finite time, while the species with the smallest reproduction-predation rate is the most likely to be the surviving one (law of the weakest). Here we model environmental (external) noise by assuming that the reproduction-predation rate of the strongest species (the fastest to reproduce and predate) in a given static environment randomly switches between two values corresponding to more and less favorable external conditions. We study the joint effect of environmental and demographic noise on the species survival probabilities and on the mean extinction time. In particular, we investigate whether the survival probabilities follow the law of the weakest and analyze their dependence on the external noise intensity and switching rate. Remarkably, when, on average, there is a finite number of switches prior to extinction, the survival probability of the predator of the species whose reaction rate switches typically varies nonmonotonically with the external noise intensity (with optimal survival about a critical noise strength). We also outline the relationship with the case where all reaction rates switch on markedly different time scales.
42 CFR 413.312 - Methodology for calculating rates.
2010-10-01
... Determined Payment Rates for Low-Volume Skilled Nursing Facilities, for Cost Reporting Periods Beginning... routine service cost limits; (ii) A wage index to adjust for area wage differences; and (iii) The most... of rates published in the Federal Register under the authority of § 413.320, CMS announces the wage...
Chest compression rates and survival following out-of-hospital cardiac arrest.
Idris, Ahamed H; Guffey, Danielle; Pepe, Paul E; Brown, Siobhan P; Brooks, Steven C; Callaway, Clifton W; Christenson, Jim; Davis, Daniel P; Daya, Mohamud R; Gray, Randal; Kudenchuk, Peter J; Larsen, Jonathan; Lin, Steve; Menegazzi, James J; Sheehan, Kellie; Sopko, George; Stiell, Ian; Nichol, Graham; Aufderheide, Tom P
2015-04-01
Guidelines for cardiopulmonary resuscitation recommend a chest compression rate of at least 100 compressions/min. A recent clinical study reported optimal return of spontaneous circulation with rates between 100 and 120/min during cardiopulmonary resuscitation for out-of-hospital cardiac arrest. However, the relationship between compression rate and survival is still undetermined. Prospective, observational study. Data is from the Resuscitation Outcomes Consortium Prehospital Resuscitation IMpedance threshold device and Early versus Delayed analysis clinical trial. Adults with out-of-hospital cardiac arrest treated by emergency medical service providers. None. Data were abstracted from monitor-defibrillator recordings for the first five minutes of emergency medical service cardiopulmonary resuscitation. Multiple logistic regression assessed odds ratio for survival by compression rate categories (compression fraction and depth, first rhythm, and study site. Compression rate data were available for 10,371 patients; 6,399 also had chest compression fraction and depth data. Age (mean±SD) was 67±16 years. Chest compression rate was 111±19 per minute, compression fraction was 0.70±0.17, and compression depth was 42±12 mm. Circulation was restored in 34%; 9% survived to hospital discharge. After adjustment for covariates without chest compression depth and fraction (n=10,371), a global test found no significant relationship between compression rate and survival (p=0.19). However, after adjustment for covariates including chest compression depth and fraction (n=6,399), the global test found a significant relationship between compression rate and survival (p=0.02), with the reference group (100-119 compressions/min) having the greatest likelihood for survival. After adjustment for chest compression fraction and depth, compression rates between 100 and 120 per minute were associated with greatest survival to hospital discharge.
Energy Technology Data Exchange (ETDEWEB)
Shim, Yong Woon; Lee, Jong Tae; Yoo, Hyung Sik; Lee, Do Yun; Jun, Pyoung Jun; Chang, So Yong [Yonsei Univ. College of Medicine, Seoul (Korea, Republic of)
1996-06-01
To compare the survival rates of patients with hepatoma using different methods of transcatheter arterial chemoemblization(THAE). Four hundred and eighty three patients with hepatoma diagnosed by biopsy, serum alpha-fetoprotein, abdominal CT scan, abdominal ultrasonography or hepatic angiography were included, but not all had received surgical treatment. They were divided onto two groups according to Child's classification and into subgroups according to different methods of THAE. Five-tear survival rates among these groups were retrospectively compared. The patients were aged between 24 and 85(mean, 58) ; male to female ratio was 324 : 61 for those who received THAE (369 : 87 when only hepatic angiography was considered.). In the group with more than a single episode of chemoembolization, regardless of Child's classification, a better survival rate compared to the other groups with or without concommitant radiotherapy or without chemoembolization was noted. There was no difference in the survival rate of patients with multiple chemoembolization. moreover, no difference in this rate was observed no matter what chemotherapeutic agents, including Adriamycin, Cis-Diaminedichloroplatinum of I-131-Lipiodol, were used. Amortization by gelfoam in conjuction with Adriamycin resulted in no difference in survival rate regardless of frequency of chemoembolization. An improved survival rate was seen when multiple episodes of chemoembolization were applied, but no difference was seen when there was concomitant application of either gelfoam or radiotherapy. Two different chemotherapeutic agents, Adriamycin and Cis-Diaminedichloroplatinum, were used, but there was no difference between them in their effect on survival rates.
Survival and growth rates of juvenile salmonids reared in lowland streams
Directory of Open Access Journals (Sweden)
Golski Janusz
2016-12-01
Full Text Available The aim of this study was to assess the efficiency of propagating juvenile trout, Salmo trutta L. in small lowland streams and to evaluate the impact of the environmental conditions in the streams on the juvenile fish. Brown trout (Salmo trutta fario and sea trout (Salmo trutta trutta early fry fed under controlled conditions were used to stock third-order lowland streams. During summer, fall, and spring catches, fry were counted, measured, and weighed. The following parameters were calculated using the data collected: fry stocking density (ind. m-2; survival; specific mortality rate (SMR; length range; mean specimen length; body weight; mean body weight; specific growth rate (SGR; body condition (Fulton’s index. The ichthyological studies were accompanied by simultaneous analyses of environmental conditions that were performed monthly, and benthic macroinvertebrates were sampled in spring and fall. No differences were observed in the biological parameters analyzed between sea trout and brown trout. Variability in environmental parameters such as temperature, oxygenation, conductivity, and stream width and depth were associated with differentiation in the biological parameters of the fry. The results clearly indicate that the considerable potential of small lowland streams for the propagation of salmonid juvenile stages is currently underexploited.
The survival rate of self-immolators in Kermanshah Province 2010- 2011
Directory of Open Access Journals (Sweden)
Farid Najafi
2013-12-01
Full Text Available Background: Self-immolation is one of the most violent methods of suicide, which is spreading in Iran. The highest rate of deaths due to committing suicide and self-immolation in Iran is observed in Kermanshah province. This research was conducted to study the survival rate and the factors that influence survival among the ones who commit self-immolation in Kermanshah province. Methods: In this study, all the cases who did not survive, as well as all the ones who were hospitalized due to self-immolation in Kermanshah province during 2010 and 2011 were examined. The Kaplan-Meier method was used to estimate the survival function, and in order to do the comparisons, Logrank test and Cox Regression were employed using Stata 12 software. Results: The results indicated that during 2010 and 2011, 343 individuals committed self-immolation in Kermanshah Province, while, 288 (84% were women. Also, it was found that 184 (53% did not survive, the mean and median of survival time in those who committed suicide deliberately, were 33±2.6 and 11±2 days respectively. Estimation of survival rate using Logrank test indicated that survival rate had a significant relationship with age, mental disorders, drug addiction, and TBSA (Total Body Surface Area, while it did not suggest a statistically significant relationship with gender, marital status and cause of injury. After multivariate analysis using Cox regression, only two variables of age and TBSA could remain in the model and the other variables were excluded from the model. Conclusion: The death toll due to self-immolation is very high and the mean and median of survival time among the people who committed self-immolation is very low. Therefore, it is recommended that remedial action be performed quickly without wasting time.
Calculating Outcrossing Rates used in Decision Support Systems for Ships
DEFF Research Database (Denmark)
Nielsen, Ulrik Dam
2008-01-01
Onboard decision support systems (DSS) are used to increase the operational safety of ships. Ideally, DSS can estimate - in the statistical sense - future ship responses on a time scale of the order of 1-3 hours taking into account speed and course changes. The calculations depend on both...... analysis, and the paper derives and describes the main ideas. The concept is illustrated by an example, where the limit state of a non-linear ship response is considered. The results from the parallel system analysis are in agreement with corresponding Monte Carlo simulations. However, the computational...
Calculation of multigroup reaction rates for the Ghana Research ...
African Journals Online (AJOL)
The discrete ordinate spatial model, which pro-vides solution to the differential form of the transport equation by the Carlson-SN (N=4) approach was adopted to solve the Ludwig-Boltzmann multigroup neutron transport equation for this analysis. The results show that for any fissile resonance absorber, the reaction rates ...
Exact comparison of dose rate measurements and calculation of TN12/2 packages
International Nuclear Information System (INIS)
Taniuchi, H.; Matsuda, F.
1998-01-01
Both of dose rate measurements of TN 12/2 package and calculations by Monte Carlo code MORSE in SCALE code system and MCNP were performed to evaluate the difference between the measurement and the calculation and finding out the cause of the difference. The calculated gamma-ray dose rates agreed well with measured ones, but calculated neutron dose rates overestimated more than a factor of 1.7. When considering the cause of the difference and applying the modification into the neutron calculation, the calculated neutron dose rates become to agree well, and the factor decreased to around 1.3. (authors)
Sample size calculation for comparing two negative binomial rates.
Zhu, Haiyuan; Lakkis, Hassan
2014-02-10
Negative binomial model has been increasingly used to model the count data in recent clinical trials. It is frequently chosen over Poisson model in cases of overdispersed count data that are commonly seen in clinical trials. One of the challenges of applying negative binomial model in clinical trial design is the sample size estimation. In practice, simulation methods have been frequently used for sample size estimation. In this paper, an explicit formula is developed to calculate sample size based on the negative binomial model. Depending on different approaches to estimate the variance under null hypothesis, three variations of the sample size formula are proposed and discussed. Important characteristics of the formula include its accuracy and its ability to explicitly incorporate dispersion parameter and exposure time. The performance of the formula with each variation is assessed using simulations. Copyright © 2013 John Wiley & Sons, Ltd.
Secondary standard dosimetry system with automatic dose/rate calculation
International Nuclear Information System (INIS)
Duftschmid, K.E.; Bernhart, J.; Stehno, G.; Klosch, W.
1980-01-01
A versatile and automated secondary standard instrument has been designed for quick and accurate dose/rate measurement in a wide range of radiation intensity and quality (between 1 μR and 100 kR; 0.2 nC/kg - 20C/kg) for protection and therapy level dosimetry. The system is based on a series of secondary standard ionization chambers connected to a precision digital current integrator with microprocessor circuitry for data evaluation and control. Input of measurement parameters and calibration factors stored in an exchangeable memory chip provide computation of dose/rate values in the desired units. The ionization chambers provide excellent long-term stability and energy response and can be used with internal check sources to test validity of calibration. The system is a useful tool particularly for daily measurements in a secondary standard dosimetry laboratory or radiation therapy center. (H.K.)
Dose rate effects on survival of two insect species which commonly infest stored corn
International Nuclear Information System (INIS)
Adem, E.; Uribe, R.M.; Watters, F.L.
1979-01-01
A study of the dose rate effects on survival of two species of insects which commonly infest commercial maize in Mexico was undertaken using 60 Co γ radiation and 1.0 MeV electrons, to determine whether an optimum dose rate exists for the irradiation of grain infested with these insects. Experiments have shown that the effectiveness of γ and electron irradiation were not influenced by dose rates from 10 to 120 Gy/min for 60 Co and 35 to 300 Gy/min for electrons when the insects were irradiated at 2500 Gy. Survival curves for each species are presented for both types of radiation. (author)
Increasing Winter Maximal Metabolic Rate Improves Intrawinter Survival in Small Birds.
Petit, Magali; Clavijo-Baquet, Sabrina; Vézina, François
Small resident bird species living at northern latitudes increase their metabolism in winter, and this is widely assumed to improve their chances of survival. However, the relationship between winter metabolic performance and survival has yet to be demonstrated. Using capture-mark-recapture, we followed a population of free-living black-capped chickadees (Poecile atricapillus) over 3 yr and evaluated their survival probability within and among winters. We also measured the size-independent body mass (M s ), hematocrit (Hct), basal metabolic rate (BMR), and maximal thermogenic capacity (Msum) and investigated how these parameters influenced survival within and among winters. Results showed that survival probability was high and constant both within (0.92) and among (0.96) winters. They also showed that while M s , Hct, and BMR had no significant influence, survival was positively related to Msum-following a sigmoid relationship-within but not among winter. Birds expressing an Msum below 1.26 W (i.e., similar to summer levels) had a winter. Our data therefore suggest that black-capped chickadees that are either too slow or unable to adjust their phenotype from summer to winter have little chances of survival and thus that seasonal upregulation of metabolic performance is highly beneficial. This study is the first to document in an avian system the relationship between thermogenic capacity and winter survival, a proxy of fitness.
Evidence that a Highway Reduces Apparent Survival Rates of Squirrel Gliders
Directory of Open Access Journals (Sweden)
Sarah C. McCall
2010-09-01
Full Text Available Roads and traffic are prominent components of most landscapes throughout the world, and their negative effects on the natural environment can extend for hundreds or thousands of meters beyond the road. These effects include mortality of wildlife due to collisions with vehicles, pollution of soil and air, modification of wildlife behavior in response to noise, creation of barriers to wildlife movement, and establishment of dispersal conduits for some plant and animal species. In southeast Australia, much of the remaining habitat for the squirrel glider, Petaurus norfolcensis, is located in narrow strips of Eucalyptus woodland that is adjacent to roads and streams, as well as in small patches of woodland vegetation that is farther from roads. We evaluated the effect of traffic volume on squirrel gliders by estimating apparent annual survival rates of adults along the Hume Freeway and nearby low-traffic-volume roads. We surveyed populations of squirrel gliders by trapping them over 2.5 years, and combined these data with prior information on apparent survival rates in populations located away from freeways to model the ratio of apparent annual survival rates in both site types. The apparent annual survival rate of adult squirrel gliders living along the Hume Freeway was estimated to be approximately 60% lower than for squirrel gliders living near local roads. The cause of the reduced apparent survival rate may be due to higher rates of mortality and/or higher emigration rates adjacent to the Hume Freeway compared with populations near smaller country roads. Management options for population persistence will be influenced by which of these factors is the primary cause of a reduced apparent survival rate.
Calculation of turnover rates in stable-isotope studies
International Nuclear Information System (INIS)
Wootton, R.; Ford, G.C.; Cheng, K.N.; Halliday, D.
1985-01-01
In a comparison of glucose turnover measured with 2 H-glucose and with 13 C-glucose Tserng and Kalhan used five apparently different equations and obtained conflicting answers. There is, however, no difference in principle between the use of a stable isotope as a tracer and the use of a radioactive isotope, and the rate of appearance of tracee in a steady-state system (the turnover) can therefore be shown to be proportional to the equilibrium dilution of the infused tracer. Because the sensitivity of measurement of this dilution made using a gas chromatograph-mass spectrometer is lower than that made by radioactivity measurement, the contribution to the measured turnover rate due to the infusate cannot be neglected, as it usually is in radioisotope work. A convenient calibration curve to establish this dilution is the mole ratio of the pure infusate against the area ratio for the relevant ions. Tserng and Kalhan's apparently conflicting results for glucose-turnover using 13 C-glucose as the tracer can all be shown to amount to approximately 11.6 μmol min -1 kg -1 . This value is only slightly lower (0.05 2 H-glucose as the tracer and supports the use of 13 C-glucose as an alternative. (author)
Directory of Open Access Journals (Sweden)
M Maghsoodloo
2002-09-01
Full Text Available Introduction: For the time being we have considered that the myocardial infarction is an increasing event in Islamic Republic of Iran and there are many procedures and methods which can help us to diminish the number of death from this ongoing event. The main aim of this research is to determine the survival rate in those patients who have had acute myocardial infarction and the association of it with different variables. Methods and Materials: The present research is a descriptive case-series study which evaluates the 100 cases of acute myocardial infarction who had been admitted in Tehran Emam Khomeini Hospital during the year 1999. Results: The mean age of patients was 57 years. The peak of attack rates was in spring and autumn. Investigating of the past history of these patients reviled that 41 percent had been smokers, 63.5 percent have had the history of previous ischemic heart disease, 41 percent have had hyper cholestrolemia, 34 percent had hypertension, 18 percent had diabetes mellitus, 9 percent had mitral rigurgitation and 9 percent had heart block. The Survival rate in our study has been calculated 68 percent in first 28 days of disease. Conclusion: In our study we concluded that there is significant correlation between survival rate and past history of hypertension, ischemic heart disease, tobacco smoking and clip classification.
Correia, Francisco; Gouveia, Sónia; Felino, António Campos; Costa, Ana Lemos; Almeida, Ricardo Faria
To evaluate the differences between the survival rates of implants placed in patients with no history of periodontal disease (NP) and in patients with a history of chronic periodontal disease (CP). A retrospective cohort study was conducted in which all consenting patients treated with dental implants in a private clinic in Oporto, Portugal, from November 2, 2002 through February 11, 2011 were included. All patients were treated consecutively by the same experimental operator. This study aimed to analyze how the primary outcomes (presence of disease, time of placement, and time of loading) and the secondary outcomes (severity-generalized periodontitis, brand, implant length, prosthesis type, prosthesis metal-ceramic extension) influence the survival rate of dental implants. The survival analysis was performed through the Kaplan-Meier method, and the equality of survival distributions for all groups was tested with the log-rank test with a significance level of .05 for all comparisons. The sample consisted of 202 patients (47% NP and 53% CP) and 689 implants (31% NP and 69% CP). The survival rate in the NP and CP groups showed no statistically significant differences (95.8% versus 93.1%; P ≥ .05). Implants were lost before loading in 54.9% of the cases. The majority of the implants were lost in the first year and stabilized after the second year. Survival rates in the NP and CP patients showed no statistically significant differences when comparing the following factors: subclassification of the disease, implant brands, implant length (short/standard), type of prosthesis, extension of the prosthesis metal-ceramic, and time of placement and loading (P ≥ .05). This work disclosed no statistically significant differences in terms of survival rates when compared with the control group. Placing implants in patients with a history of periodontal disease appears to be viable and safe.
Evaluation of the Survival Rate and Bone Loss of Implants with Various Lengths
Directory of Open Access Journals (Sweden)
AR. Rokn
2006-12-01
Full Text Available Statement of Problem: The replacement of missing teeth with implant-associated restorations has become a widely used treatment modality in recent years. The length of dental implants may be a critical factor in achieving and maintaining osseointegration.Purpose: The aim of this study was to evaluate the survival rate and bone loss of dental implants with different lengthsMaterials and Methods: A retrospective cohort study was performed on 60 ITI-system implants, evenly distributed into three groups including 8, 10 and 12 mm high implants in the posterior segments of both jaws. Demographic information, oral hygiene,cigarette smoking, implant length, duration of implant placement (at least 24 months,bleeding on probing index and pocket probing depth were recorded for all participants.Bone loss was calculated using pre- and post-operative panoramic radiographs.Results: The mean rate of bone loss was different among the three groups and were found to be 0.21 (0.45, 0.3 (0.41 and 0.43 (0.55 mm in the 8, 10, and 12 mm high implants, respectively. Neither mean bone loss nor bleeding on probing index showed significant differences with implant length. A significant correlation was found between implant length and pocket probing depth (P<0.0001.Conclusion: The results of this study suggest that both short (8 mm high and long (10 or 12 mm high implants may be used with nearly equal success rates in the posterior segments of the jaws.
Halliday, Jane; Collins, Veronica; Riley, Merilyn; Youssef, Danielle; Muggli, Evelyne
2009-01-01
With this study we aimed to compare survival rates for children with Down syndrome in 2 time periods, 1 before prenatal screening (1988-1990) and 1 contemporaneous with screening (1998-2000), and to examine the frequency of comorbidities and their influence on survival rates. Record-linkage was performed between the population-based Victorian Birth Defects Register and records of deaths in children up to 15 years of age collected under the auspice of the Consultative Council on Obstetric and Pediatric Mortality and Morbidity. Cases of Down syndrome were coded according to the presence or absence of comorbidities by using the International Classification of Diseases, Ninth Revision classification of birth defects. Kaplan-Meier survival functions and log rank tests for equality of survival distributions were performed. Of infants liveborn with Down syndrome in 1998-2000, 90% survived to 5 years of age, compared with 86% in the earlier cohort. With fetal deaths excluded, the proportion of isolated Down syndrome cases in the earlier cohort was 48.7% compared with 46.1% in the most recent cohort. In 1988-1990 there was at least 1 cardiac defect in 41.1% of cases and in 45.4% in 1998-2000. There was significant variation in survival rates for the different comorbidity groupings in the 1988-1990 cohort, but this was not so evident in the 1998-2000 cohort. Survival of children with Down syndrome continues to improve, and there is an overall survival figure of 90% to at least 5 years of age. It is clear from this study that prenatal screening technologies are not differentially ascertaining fetuses with Down syndrome and additional defects, because there has been no proportional increase in births of isolated cases with Down syndrome.
Improving village poultry’s survival rate through community-based poultry health management
DEFF Research Database (Denmark)
Sodjinou, Epiphane; Henningsen, Arne; Koudande, Olorounto D.
Community-based poultry health management (CBM) is a strategy for village poultry improvement based on the installment of “poultry interest groups” in experimental villages. These groups serve as a channel for the dissemination of village poultry improvement technologies. The use of CBM is due...... to the fact that village poultry farming is practiced in a total or partial scavenging system which gives the impression that all the birds in the village belong to the same flock. Accordingly, actions that target all farmers of the same village may have a larger impact on the village poultry’s survival rate...... than actions that target individual producers. The objective of this study is to assess the impact of CBM on the survival rate of village poultry. Based on data collected on 353 poultry keepers, the study shows that CBM significantly improves the survival rate of village poultry. The adoption...
Improving village poultry's survival rate through community-based poultry health management
DEFF Research Database (Denmark)
Sodjinou, Epiphane; Henningsen, Arne; Koudande, Olorounto Delphin
2012-01-01
Community-based poultry health management (CBM) is a strategy for village poultry improvement based on the installment of “poultry interest groups” in experimental villages. These groups serve as a channel for the dissemination of village poultry improvement technologies. The use of CBM is due...... to the fact that village poultry farming is practiced in a total or partial scavenging system which gives the impression that all the birds in the village belong to the same flock. Accordingly, actions that target all farmers of the same village may have a larger impact on the village poultry's survival rate...... than actions that target individual producers. The objective of this study is to assess the impact of CBM on the survival rate of village poultry. Based on data collected on 353 poultry keepers, the study shows that CBM significantly improves the survival rate of village poultry. The adoption...
[Survival rate for breast cancer in Rabat (Morocco) 2005-2008].
Mechita, Nada Bennani; Tazi, Mohammed Adnane; Er-Raki, Abdelouahed; Mrabet, Mustapha; Saadi, Asma; Benjaafar, Noureddine; Razine, Rachid
2016-01-01
Breast cancer is a public health problem in Morocco. This study aims to estimate the survival rate for patients with breast cancer living in Rabat. We conducted a prognostic study of female patients with breast cancer diagnosed during 2005-2008, living in Rabat and whose data were recorded in the Rabat Cancer Registry. The date of inclusion in this study corresponded with the date on which cancer was histologically confirmed. Survival rate was estimated using the Kaplan-Meier method and the comparison between the different classes of a variable was made using the log rank test. The study of factors associated with survival was performed using the Cox model. During the study period 628 cases of breast cancer were collected. Mortality rate was 19.9%. Overall 1-year survival rate was 97.1%, 89.2% at 3 years and 80.6% at 5 years. In multivariate analysis, breast cancer survival was statistically lower in patients over 70 years of age (p <0.001) with large tumor size (p < 0.001), advanced-stage adenopathies (p = 0.007), metastases (p < 0.001) and not using hormone therapy (p = 0.002). Large tumor size and metastases are poor prognostic factors in breast cancer, hence the need to strengthen screening programs.
Photoionization cross sections and Auger rates calculated by many-body perturbation theory
International Nuclear Information System (INIS)
Kelly, H.P.
1976-01-01
Methods for applying the many body perturbation theory to atomic calculations are discussed with particular emphasis on calculation of photoionization cross sections and Auger rates. Topics covered include: Rayleigh--Schroedinger theory; many body perturbation theory; calculations of photoionization cross sections; and Auger rates
Accurate quantum calculations of the reaction rates for H/D+ CH4
Harrevelt, R. van; Nyman, G.; Manthe, U.
2007-01-01
In previous work [T. Wu, H. J. Werner, and U. Manthe, Science 306, 2227 (2004)], accurate quantum reaction rate calculations of the rate constant for the H+CH4 -> CH3+H-2 reaction have been presented. Both the electronic structure calculations and the nuclear dynamics calculations are converged with
Self-rated health as a predictor of survival among patients with advanced cancer.
Shadbolt, Bruce; Barresi, Jane; Craft, Paul
2002-05-15
Evidence is emerging about the strong predictive relationship between self-rated health (SRH) and survival, although there is little evidence on palliative populations where an accurate prediction of survival is valuable. Thus, the relative importance of SRH in predicting the survival of ambulatory patients with advanced cancer was examined. SRH was compared to clinical assessments of performance status, as well as to quality-of-life measures. By use of a prospective cohort design, 181 patients (76% response rate) with advanced cancer were recruited into the study, resurveyed at 18 weeks, and observed to record deaths. The average age of patients was 62 years (SD = 12). The median survival time was 10 months. SRH was the strongest predictor of survival from baseline. Also, a Cox regression comparing changes in SRH over time yielded hazard ratios suggesting the relative risk (RR) of dying was greater for fair ratings at 18 weeks (approximately 3 times) compared with consistent good or better ratings; the RR was even greater (4.2 and 6.2 times) for poor ratings, especially when ratings were poor at baseline and 18 weeks (31 times). Improvement in SRH over time yielded the lowest RR. SRH is valid, reliable, and responsive to change as a predictor of survival of advanced cancer. These qualities suggest that SRH should be considered as an additional tool by oncologists to assess patients. Similarly, health managers could use SRH as an indicator of disease severity in palliative care case mix. Finally, SRH could provide a key to help us understand the human side of disease and its relationship with medicine.
Aquilino, S A; Shugars, D A; Bader, J D; White, B A
2001-05-01
Failure to replace a single missing posterior tooth may lead to a variety of dental problems, which may ultimately result in tooth loss. However, little is known about the fate of the adjacent teeth if a missing posterior tooth is not replaced. This retrospective study evaluated the survival of teeth adjacent to treated and untreated posterior bounded edentulous spaces. Data were obtained from electronic treatment records from the Kaiser Permanente Dental Care Program, Portland, Ore. A final sample of 317 patients who met the study inclusion criteria was identified. Each bounded edentulous space was placed in 1 of 3 treatment categories: untreated, restored with a fixed partial denture, or restored with a removable partial denture. Subsequent treatment and the status of the teeth adjacent to the bounded edentulous space were followed through December 1999. Ten-year Kaplan-Meier survival estimates were generated for each treatment group, and differences in survival were evaluated with the log-rank chi-square test (alpha=.05). There was a significant difference in survival among the 3 treatment categories (P=.005). Spaces restored with a fixed partial denture had longer 10-year survival estimates (92%) than those that remained untreated (81%). Spaces restored with a removable partial denture had the poorest 10-year survival rate (56%). Under the conditions and selection bias associated with this retrospective study, the survival of teeth adjacent to a single posterior edentulous space was negatively associated with removable partial denture placement compared with no treatment or the use of a fixed partial denture.
International Nuclear Information System (INIS)
Malzoni, Carlos Eduardo
1996-01-01
The surgical treatment of gastric cancer has better long-term survival rates when performed in patients with early gastric cancer. Worse results are obtained in treatment of advanced gastric cancer. Most patients in west centers are treated in advanced stages. A great number of them go through a surgical treatment unable by itself to cure them. the frequent local recurrence caused by failure of the surgical treatment has been keeping poor survival rates in patients with advanced gastric cancer for decades. The desire of improving survival is the reason of the use of adjuvant therapies. This paper achieved the retrospective study of the influence of preoperative radiation therapy (2000 cGy) in long-term survival rates (120 months) of patients with advanced gastric cancer on stages IIIa, IIIb and IV. The possible injuries caused in the liver and kidney were observed also as well as first group was treated by surgical and radiation therapies and the second received surgical treatment only. There was no statistical difference between the two groups when sex, age, race, occurrence of other diseases, nutritional assessment, TNM stage, occurrence of obstruction or bleeding caused by tumor, surgical procedure and hepatic and renal function were considered. Survival rates and changes on hepatic and renal function were statistically compared. The results showed a statistic improvement on the long-term survival rates of stage IIIa patients treated by preoperative radiation therapy. No statistic difference was observed on hepatic or renal function between the groups. No adverse influence of radiation therapy method was detected by the used parameters. There was no statistical difference between the two groups when immediate surgical complications were considered. (author)
31 CFR 356.21 - How are awards at the high yield or discount rate calculated?
2010-07-01
... discount rate calculated? 356.21 Section 356.21 Money and Finance: Treasury Regulations Relating to Money... high yield or discount rate calculated? (a) Awards to submitters. We generally prorate bids at the highest accepted yield or discount rate under § 356.20(a)(2) of this part. For example, if 80.15% is the...
Fronczak, David L.; Andersen, David E.; Hanna, Everett E.; Cooper, Thomas R.
2015-01-01
Several surveys have documented the increasing population size and geographic distribution of Eastern Population greater sandhill cranes Grus canadensis tabida since the 1960s. Sport hunting of this population of sandhill cranes started in 2012 following the provisions of the Eastern Population Sandhill Crane Management Plan. However, there are currently no published estimates of Eastern Population sandhill crane survival rate that can be used to inform harvest management. As part of two studies of Eastern Population sandhill crane migration, we deployed solar-powered global positioning system platform transmitting terminals on Eastern Population sandhill cranes (n = 42) at key concentration areas from 2009 to 2012. We estimated an annual survival rate for Eastern Population sandhill cranes from data resulting from monitoring these cranes by using the known-fates model in the MARK program. Estimated annual survival rate for adult Eastern Population sandhill cranes was 0.950 (95% confidence interval = 0.885–0.979) during December 2009–August 2014. All fatalities (n = 5) occurred after spring migration in late spring and early summer. We were unable to determine cause of death for crane fatalities in our study. Our survival rate estimate will be useful when combined with other population parameters such as the population index derived from the U.S. Fish and Wildlife Service fall survey, harvest, and recruitment rates to assess the effects of harvest on population size and trend and evaluate the effectiveness of management strategies.
Breast cancer survival rates among Seventh-day Adventists and non-Seventh-day Adventists.
Zollinger, T W; Phillips, R L; Kuzma, J W
1984-04-01
Survival rates were compared among 282 Seventh-day Adventists and 1675 other white female cancer cases following diagnosis during the 30-year period, 1946 to 1976, at two California hospitals owned and operated by the Seventh-day Adventist Church. The Adventist women had a more favorable 5-year relative survival pattern than the other women (69.7% vs. 62.9%) as well as a higher probability of not dying of breast cancer. The differences, however, were no longer significant when stage at diagnosis was taken into account. It seems likely that the lower breast cancer death rates reported among Seventh-day Adventist women as compared with the general population result in part from better survival patterns due to earlier diagnosis and treatment.
Bouwer, Gustav; Nardini, Luisa; Duncan, Frances D
2009-04-01
To determine the effect of sublethal doses of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus (HearSNPV) on the metabolic rate of H. armigera, the respiration rates of third instar H. armigera larvae inoculated with sublethal doses of HearSNPV were evaluated. Respiration rates, measured as the rate of CO(2) production (VCO(2)), were recorded daily using closed-system respirometry. By 4 days post-inoculation (dpi), the metabolic rates of LD(25) or LD(75) survivors were significantly higher than that of uninoculated controls. When dose data were pooled, the VCO(2) values of larvae that survived inoculation (0.0288mlh(-1)), the uninoculated controls (0.0250mlh(-1)), and the larvae that did not survive inoculation (0.0199mlh(-1)) differed significantly from one another. At 4dpi, the VCO(2) of the uninoculated controls were significantly lower than the VCO(2) of inoculation survivors, but significantly higher than the VCO(2) of inoculation non-survivors. Inoculation survivors may have had high metabolic rates due to a combination of viral replication, organ damage, and an energy-intensive induced cellular immune response. The high 4dpi metabolic rate of inoculation survivors may reflect an effective immune response and may be seen as the metabolic signature of larvae that are in the process of surviving inoculation with HearSNPV.
Exploring location influences on firm survival rates using parametric duration models
Manzato, G.G.; Arentze, T.A.; Timmermans, H.J.P.; Ettema, D.F.; Timmermans, H.J.P.; Vries, de B.
2010-01-01
Using parametric duration models applied to an office firm dataset, we carried out an exploratory study about the location influences on firm survival rates. Amongst the variables included, we found that accessibility to infrastructure supply, regional effects, demographic and economic aspects, and
Exploring location influences on firm survival rates using parametric duration models
Manzato, G.G.; Arentze, T.A.; Timmermans, H.J.P.; Ettema, D.F.
2011-01-01
Using parametric duration models applied to an office firm dataset, we carried out an exploratory study about the location influences on firm survival rates. Amongst the variables included, we found that accessibility to infrastructure supply, regional effects, demographic and economic aspects, and
Exploration of location influences on firm survival rates using parametric duration models
Manzato, G.G.; Arentze, T.A.; Timmermans, H.J.P.; Ettema, D.F.
2011-01-01
This study explored the influences of location on business firm survival rates with the use of parametric duration models applied to a data set. Of the variables included, those found to be the most significant were accessibility to infrastructure supply, regional effects, demographic and economic
Contribution of screening and survival differences to racial disparities in colorectal cancer rates
I. Lansdorp-Vogelaar (Iris); K.M. Kuntz (Karen); A.B. Knudsen (Amy); M. van Ballegooijen (Marjolein); A. Zauber (Ann); A. Jemal (Ahmedin)
2012-01-01
textabstractBackground: Considerable disparities exist in colorectal cancer (CRC) incidence and mortality rates between blacks and whites in the United States. We estimated how much of these disparities could be explained by differences in CRC screening and stage-specific relative CRC survival.
A method for studying post-fledging survival rates using data from ringing recoveries
Thomson, D.L.; Baillie, S.R.; Peach, W.J.
1999-01-01
We present a method for studying post-fledging survival rates from data on national ringing recoveries. The approach extends the classical two-age-class models of Brownie et al. (1985) to include a third age-class of birds ringed as nestlings. The models can incorporate age-class-specific and
Blacquiere, T.
2010-01-01
Imidacloprid is a commonly used systemic insecticide which can induce several sublethal effects. Previous research has not shown any increased mortality in bees that were fed with sublethal doses. However, there is very little research conducted with the focus on survival rate of honeybees in the
38 CFR 3.24 - Improved pension rates-Surviving children.
2010-07-01
... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Improved pension rates-Surviving children. 3.24 Section 3.24 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3.24 Improved pension...
estimated glomerular filtration rate and risk of survival in acute stroke
African Journals Online (AJOL)
2014-03-03
Mar 3, 2014 ... ESTIMATED GLOMERULAR FILTRATION RATE AND RISK OF SURVIVAL IN ACUTE STROKE. E. I. Okaka, MBBS, FWACP, F. A. Imarhiagbe, MBChB, FMCP, F. E. Odiase, MBBS, FMCP, O. C. A. Okoye, MBBS, FWACP,. Department of Medicine, University of Benin Teaching Hospital, Benin City, Nigeria.
Survival rates in the Czech Republic of introduced plants known as wool aliens
Czech Academy of Sciences Publication Activity Database
Pyšek, Petr
2005-01-01
Roč. 7, - (2005), s. 567-576 ISSN 1387-3547 R&D Projects: GA ČR(CZ) GA526/00/1443 Institutional research plan: CEZ:AV0Z60050516 Keywords : wool aliens * survival rate * naturalization Subject RIV: EF - Botanics
Oral cancer incidence and survival rates in the Republic of Ireland, 1994-2009.
LENUS (Irish Health Repository)
Ali, Hala
2016-12-20
Oral cancer is a significant public health problem world-wide and exerts high economic, social, psychological, and physical burdens on patients, their families, and on their primary care providers. We set out to describe the changing trends in incidence and survival rates of oral cancer in Ireland between 1994 and 2009.
Dental implant survival rate in well-controlled diabetic patients. A systematic review.
Directory of Open Access Journals (Sweden)
Heber Arbildo
2015-12-01
Full Text Available Background: Dental implants have now become one of the most popular options for replacing a missing tooth. On the other hand, diabetes mellitus is a systemic disease that affects a large part of the population and is generally considered an absolute or relative contraindication to implant therapy. Aim: To determine the survival rate of dental implants in controlled diabetic patients through a systematic review. Material and methods: A systematic search in Pubmed, SciELO and RedALyC databases was performed. The selection criteria were: studies published in the last 10 years, with at least 20 controlled diabetic patients, reporting survival rate and number of implants placed, with follow-up periods equal to or longer than 1 year, including a control group of healthy patients. Methodological quality was analyzed with the follwing scales: Jadad and Downs & Black’s CMQ. Results: Three articles with a follow-up period between 1 and 12 years were analyzed. The overall survival rate of dental implants in diabetic controlled patients was 97.43%. Conclusion: The reviewed literature suggests that survival rate of dental implants in well-controlled diabetic patients is similar to non-diabetic patients.
38 CFR 3.10 - Dependency and indemnity compensation rate for a surviving spouse.
2010-07-01
... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Dependency and indemnity... OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3.10 Dependency and indemnity compensation rate for a surviving spouse. (a) General...
Effect of Bacillus subtilis on the growth and survival rate of shrimp ...
African Journals Online (AJOL)
The effect ofBacillus subtilis, isolated from digestive tract of Macrobrachium rosenbergii was investigated on growth and survival rate of Litopenaeus vannamei during 60 days of culture. Sixteen aquaria with four replicates were used for treatments and controls. Treatment groups were consisted of Bacillus subtilis, isolated ...
The effect of chemical weapons incineration on the survival rates of Red-tailed Tropicbirds
Schreiber, E.A.; Schenk, G.A.; Doherty, P.F.
2001-01-01
In 1992, the Johnston Atoll Chemical Agent Disposal System (JACADS) began incinerating U.S. chemical weapons stockpiles on Johnston Atoll (Pacific Ocean) where about 500,000 seabirds breed, including Red-tailed Tropicbirds (Phaethon rubricauda). We hypothesized that survival rates of birds were lower in those nesting downwind of the incinerator smokestack compared to those upwind, and that birds might move away from the area. From 1992 - 2000 we monitored survival and movements between areas upwind and downwind from the JACADS facility. We used a multi-strata mark recapture approach to model survival, probability of recapture and movement. Probability of recapture was significantly higher for birds in downwind areas (owing to greater recapture effort) and thus was an important 'nuisance' parameter to take into account in modeling. We found no differences in survival between birds nesting upwind ( 0.8588) and downwind (0.8550). There was no consistent difference in movement rates between upwind or downwind areas from year to year: differences found may be attributed to differing vegetation growth and human activities between the areas. Our results suggest that JACADS has had no documentable influence on the survival and year to year movement of Red-tailed Tropicbirds.
International Nuclear Information System (INIS)
Lu, J.; Zhang, X.; Zhao, X.
2000-01-01
Relativistic discrete-variational local density functional calculations on endohedral Gd rate at C 60 , La rate at C 60 ,Gd rate at C 74 , and La rate at C 74 are performed. All the C 60 - and C 74 -derived levels are lowered upon endohedral Gd and La doping. Both the Gd (4f 7 5d 1 6s 2 ) and La (5d 1 6s 2 ) atoms only donate their two 6s valence electrons to the cages, leaving behind their 5d electrons when they are placed at the cage centers. Compared with large-band-gap C 60 , small-band-gap C 74 and Gd (La)-metallofullerenes have strong both electron-donating and electron-accepting characters, and the calculated ionization potentials and electron affinities for them agree well with the available experimental data. (orig.)
Powell, L.A.; Conroy, M.J.; Hines, J.E.; Nichols, J.D.; Krementz, D.G.
2000-01-01
Biologists often estimate separate survival and movement rates from radio-telemetry and mark-recapture data from the same study population. We describe a method for combining these data types in a single model to obtain joint, potentially less biased estimates of survival and movement that use all available data. We furnish an example using wood thrushes (Hylocichla mustelina) captured at the Piedmont National Wildlife Refuge in central Georgia in 1996. The model structure allows estimation of survival and capture probabilities, as well as estimation of movements away from and into the study area. In addition, the model structure provides many possibilities for hypothesis testing. Using the combined model structure, we estimated that wood thrush weekly survival was 0.989 ? 0.007 ( ?SE). Survival rates of banded and radio-marked individuals were not different (alpha hat [S_radioed, ~ S_banded]=log [S hat _radioed/ S hat _banded]=0.0239 ? 0.0435). Fidelity rates (weekly probability of remaining in a stratum) did not differ between geographic strata (psi hat=0.911 ? 0.020; alpha hat [psi11, psi22]=0.0161 ? 0.047), and recapture rates ( = 0.097 ? 0.016) banded and radio-marked individuals were not different (alpha hat [p_radioed, p_banded]=0.145 ? 0.655). Combining these data types in a common model resulted in more precise estimates of movement and recapture rates than separate estimation, but ability to detect stratum or mark-specific differences in parameters was week. We conducted simulation trials to investigate the effects of varying study designs on parameter accuracy and statistical power to detect important differences. Parameter accuracy was high (relative bias [RBIAS] inference from this model, study designs should seek a minimum of 25 animals of each marking type observed (marked or observed via telemetry) in each time period and geographic stratum.
Graft survival rate of renal transplantation during a period of 10 years in Iran
Directory of Open Access Journals (Sweden)
Fatemeh Shahbazi
2015-01-01
Full Text Available Background: Kidney transplantation is a preferred treatment for many patients with end-stage renal disease (ESRD and is far more profitable than hemodialysis. Analyzing renal transplantation data can help to evaluate the effectiveness of transplantation interventions. The aim of this study was to determine the organ survival rate after kidney transplantation during a period of 10 years (March 2001-March 2011 among transplanted patients in Arak, Markazi Province, Iran. Materials and Methods: In this historical cohort study, all recipients of kidney transplantation from Arak, Markazi Province, Iran who had medical records in Valiasr Hospital and "charity for kidney patients" of Arak, Markazi Province, Iran during a period of 10 years from March 2001 to March 2011 were included. Data collected by using checklists were completed from patients′ hospital records. Kaplan-Meier method was used to determine the graft cumulative survival rate, log-rank test to compare survival curves in subgroups, and Cox regression model to define the hazard ratio and for ruling out the intervening factors. Statistical analysis was conducted by Statistical Package for the Social Sciences (SPSS 20 and Stata 11. Results: Mean duration of follow-up was 55.43 ± 42.02 months. By using the Kaplan-Meier method, the cumulative probability of graft survival at 1, 3, 5, 7, and 10 years was 99.1, 97.7, 94.3, 85.7, and 62.1%, respectively. The number of dialysis by controlling the effect of other variables had a significant association with the risk of graft failure [hazard ratios and 95% confidence interval (CI: 1.47 (1.02-2.13]. Conclusion: This study showed that the graft survival rate was satisfactory in this community and was similar to the results of single-center studies in the world. Dialysis time after transplantation was a significant predictor of survival in the recipients of kidney transplantation that should be considered.
40 CFR 75.83 - Calculation of Hg mass emissions and heat input rate.
2010-07-01
... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Calculation of Hg mass emissions and... (CONTINUED) AIR PROGRAMS (CONTINUED) CONTINUOUS EMISSION MONITORING Hg Mass Emission Provisions § 75.83 Calculation of Hg mass emissions and heat input rate. The owner or operator shall calculate Hg mass emissions...
Calculation of radiation dose rate arisen from radionuclide contained in building materials
International Nuclear Information System (INIS)
Lai Tien Thinh; Nguyen Hao Quang
2008-01-01
This paper presents some results that we used MCNP5 program to calculate radiation dose rate arisen from radionuclide in building materials. Since then, the limits of radionuclide content in building materials are discussed. The calculation results by MCNP are compared with those calculated by analytical method. (author)
A Systemic Review of Autologous Fat Grafting Survival Rate and Related Severe Complications
Directory of Open Access Journals (Sweden)
Nan-Ze Yu
2015-01-01
Full Text Available Objective: Clinical application of autologous fat grafting (AFG is quickly expanding. Despite the widely acceptance, long-term survival rate (SR of AFG remains a question not yet solved. Meanwhile, although rare, severe complications related to AFG including vision loss, stroke even death could be seen in the literature. Data Sources: A comprehensive research of PubMed database to June 2013 was performed according to guidelines of the American Society of Plastic Surgeons Fat Graft Task Force Assessment Methodology. Articles were screened using predetermined inclusion and exclusion criteria. Study Selection: Data collected included patient characteristics, surgical technique, donor site, recipient site, graft amount, and quantified measurement methods. Patient cohorts were pooled, and SR was calculated. All the severe complications were also summarized according to the different clinical characteristics. Results: Of 550 articles, 16 clinical articles and 10 animal studies met the inclusion criteria and provided quantified measurement methods. Totally, 596 patients were included. SR varied from 34% to 82% in breast and 30-83% in the facial area. Nude mice were applied to investigate human fat grafting SR (38.3-52.5% after 15 weeks. Rabbits were commonly used to study animal AFG SR (14.00-14.56% after 1-year. Totally, 21 severe complications were reported, including death (2, stroke (10, vision loss (11, 8 of which accompanied with stroke, sepsis (3, multiple abscess (1 and giant fat necrotic cyst (2. Ten of these complications happened within 10 years. Conclusions: There is no unified measurement method to evaluate fat graft SR until now and no clinical evidence to show better SR according to different donor and recipient cite. Body mass index change between pre- and postoperation may be the bias factor in evaluating fat SR. Fat embolisms of the ophthalmic artery and the middle cerebral artery are the most severe complication of AFG and still lack
International Nuclear Information System (INIS)
Szczawinska, M.
1981-01-01
The purpose of this paper is to define the effect of irradiation upon the survival rate of non-sporing bacteria (Staphylococcus aureus, Salmonella typhimurium, Escherichia coli, Pseudomonas fluorescens) during basic methods of meat preservation. The bacteria were irradiated in broth by X-rays at a dose that destroyed about 90% of the bacteria (D 10 ). The survival rate of unirradiated and irradiated bacteria during cooling and freezing, in solutions of sodium chloride, nitrates and liquid smoke, was defined. The number of microorganisms was determined directly after irradiation as well as 1, 3, 7, 14, 21 and 28 days after irradiation. The effect of irradiation upon heat resistance of the examined species of bacteria was also defined. The microorganisms were heated in broth, at 70 0 C for 1, 2 and 5 minutes. The obtained results were subjected to statistical analysis. On the basis of the research results, a faster dying rate of irradiated populations of S. aureus and E. coli during any type of preservation treatment, the lack of any reaction to irradiation regarding the survival rate of S. typhimurium, and the lack of any effect of irradiation upon the rate of deterioration of P. fluorescens during freezing and storage in a solution with 10% addition of NaCI, were observed. On the other hand, a pronounced effect of irradiation upon the lowering of the heat resistance of the bacteria, as well as delayed growth in other variants of the experiment, was determined. (author)
The calculation of coolant leak rate through the cracks using RELAP5 code
International Nuclear Information System (INIS)
Krungeleviciute, V.; Kaliatka, A.
2001-01-01
For reason to choose method of leak detection first of all it is necessary to perform evaluating thermal-hydraulic calculations. These calculations allow to determine flow rate of discharged coolant. For coolant leak rate calculations through possible cracks in Ignalina NPP pipes SQUIRT and RELAP5 thermal-hydraulic codes were used. SQUIRT is well known as computer program that predicts the leakage for cracked pipes in NPP. As this code calculates only water (at subcooled or saturated conditions) leak rate, RELAP5 code model, that calculates water and steam leak rate, was created. For model validation comparison of SQUIRT, RELAP5 and experimental results was performed. Analysis shows RELAP5 code model suitability for calculations of leak through through-wall cracks in pipes. (author)
Energy Technology Data Exchange (ETDEWEB)
HU TA
2009-10-26
Assess the steady-state flammability level at normal and off-normal ventilation conditions. The hydrogen generation rate was calculated for 177 tanks using the rate equation model. Flammability calculations based on hydrogen, ammonia, and methane were performed for 177 tanks for various scenarios.
Directory of Open Access Journals (Sweden)
Jannelle Couret
Full Text Available Many environmental factors, biotic and abiotic interact to influence organismal development. Given the importance of Aedes aegypti as a vector of human pathogens including dengue and yellow fever, understanding the impact of environmental factors such as temperature, resource availability, and intraspecific competition during development is critical for population control purposes. Despite known associations between developmental traits and factors of diet and density, temperature has been considered the primary driver of development rate and survival. To determine the relative importance of these critical factors, wide gradients of conditions must be considered. We hypothesize that 1 diet and density, as well as temperature influence the variation in development rate and survival, 2 that these factors interact, and this interaction is also necessary to understand variation in developmental traits. Temperature, diet, density, and their two-way interactions are significant factors in explaining development rate variation of the larval stages of Ae. aegypti mosquitoes. These factors as well as two and three-way interactions are significantly associated with the development rate from hatch to emergence. Temperature, but not diet or density, significantly impacted juvenile mortality. Development time was heteroskedastic with the highest variation occurring at the extremes of diet and density conditions. All three factors significantly impacted survival curves of experimental larvae that died during development. Complex interactions may contribute to variation in development rate. To better predict variation in development rate and survival in Ae. aegypti, factors of resource availability and intraspecific density must be considered in addition, but never to the exclusion of temperature.
Survival and Complication Rate of Radiation Therapy in Stage I and II Carcinoma of uterine Cervix
International Nuclear Information System (INIS)
Ma, Sun Young; Cho, Heung Lea; Sohn, Seung Chang
1995-01-01
Purpose : To analyze survival rate and late rectal and bladder complication for patients with stage with stage I and II carcinoma of uterine cervix treated by radiation alone or combined with chemotherapy. Materials and Methods : Between November 1984 and December 1993, 127 patients with stage I and II carcinoma of uterine cervix treated by radiation alone or combined therapy of radiation and chemotherapy. Retrospective analysis for survival rate was carried out on eligible 107 patients and review for complication was possible in 91 patients. The median follow-up was 47 months (range 3-118) and the median age of patients was 56 years (range 31-76). 26 patients were stage IB by FIGO classification. 40 were stage IIA and 41 were stage IIB. 86 cases were treated by radiation alone and 21 were treated by radiation and chemotherapy. 101 patients were treated with intracavitary radiation therapy (ICRT), of these, 80 were received low dose rate (LDR) ICRT and 21 were received high dose rate (HDR) ICRT. Of the patients who received LDR ICRT, 63 were treated by 1 intracavitary insertion and 17 were underwent 2 insertions. And we evaluated the external radiation dose and midline shield. Results : Acturial survival rate at 5 years was 92% for stage IB, 75% for stage IIA, 53% for stage IIB and 69% in all patients. Grade 1 rectal complications were developed in 20 cases(22%), grade 2 were in 22 cases (24%), 22 cases (24%) of grade 1 urinary complications and 17 cases (19%) of grade 2 urinary complications were observed But no patients had severe complications that needed surgical management or admission care. Maximum bladder dose for the group of patients with urinary complications was higher than that for the patients without urinary complications(7608cGy v 6960cGy, p<0.01). Maximum rectal dose for the group of patients with rectal complications was higher than that for the patients without urinary complications (7041cGy v 6269cGy, p<0.01). While there was no significant
Investigating Rates of Hunting and Survival in Declining European Lapwing Populations.
Directory of Open Access Journals (Sweden)
Guillaume Souchay
Full Text Available Understanding effects of harvest on population dynamics is of major interest, especially for declining species. European lapwing Vanellus vanellus populations increased from the 1960s until the 1980s and declined strongly thereafter. About 400,000 lapwings are harvested annually and it is thus of high conservation relevance to assess whether hunting was a main cause for the observed changes in lapwing population trends. We developed a multi-event cause-specific mortality model which we applied to a long-term ring-recovery data set (1960-2010 of > 360,000 records to estimate survival and cause-specific mortalities. We found no temporal change in survival over the last 50 years for first-year (FY and older birds (after first-year; AFY originating from different ringing areas. Mean survival was high, around 0.60 and 0.80 for FY and AFY individuals, respectively. The proportion of total mortality due to hunting was <0.10 over the study period and the estimated proportion of harvested individuals (kill rate was <0.05 in each year. Our result of constant survival indicates that demographic processes other than survival were responsible for the pronounced change in lapwing population trends in the 1980s. Our findings lend support to the hypothesis that hunting was not a significant contributor to the large-scale decline of lapwing populations. To halt the ongoing decline of European lapwing populations management should focus on life history stages other than survival (e.g. productivity. Further analyses are required to investigate the contribution of other demographic rates to the decline of lapwings and to identify the most efficient conservation actions.
Calculation methods for dissolution rate of multicomponent alloys during electrochemical machining
International Nuclear Information System (INIS)
Dikusar, A.I.; Petrenko, V.I.; Dikusar, G.K.; Ehngel'gardt, G.R.; Michukova, N.Yu.
1981-01-01
The possibility of theoretical calculation of metal dissolution rate during electrochemical mashining is considered. Two calculation techniques are compared at the example of two-component W-Re, Ni-W, Mo-Re alloys, namely: ''charge superposition'' and ''weight percents''. It is concluded that the technique of ''charge superposition'' is the only grounded calculation technique of specific rates of dissolution for alloys [ru
International Nuclear Information System (INIS)
Kuga, Hirotaka; Nishihara, Kazuyoshi; Matsunaga, Hiroaki; Suehara, Nobuhiro; Abe, Yuji; Ihara, Takaaki; Iwashita, Toshimitsu; Mitsuyama, Shoshu
2006-01-01
The purpose of this study was to evaluate the efficiency of intraoperative radiotherapy (IORT) combined with surgical resection. Subjects were consecutive 69 patients with pancreatic cancer treated with surgery alone (n=31) or surgical resection combined with IORT (n=38) in a 13 year period between 1991 and 2003. We evaluated the effects of IORT against local recurrence of cancer and patients' survival, retrospectively. Furthermore, clinicopathological factors affecting the 5-year survival rate in the two groups were comparatively investigated. The IORT group showed a significantly lower local recurrence rate of cancer than that in the surgery alone group (7.8% and 22.6%, respectively; p<0.05). The 5-year survival probability in the IORT group was significantly higher than that in the surgery alone group (29.9% and 3.4%, respectively; p<0.05). According to the Japanese classification of pancreatic cancer, cancers located in the pancreas body or tail, no local residual cancer post operative procedure (R0), low grade local cancer progression (t1, 2), and low grade intrapancreatic neural invasion (ne0, 1) were significantly better prognostic factors in the IORT group than those in the surgery alone group. There were no significant differences between the both groups in the 5-year survival rate in terms of the sex of the patients, cancer of the pancreas head, histological type, more than R1, the presence of lymph node involvement, ne2-3, and clinical stages. IORT is a useful intraoperative adjuvant therapy for pancreatic cancer, when the curative resection is achieved. Our data have suggested that IORT suppresses the local recurrence of cancer and provides the significant survival benefit for those patients. (author)
Jaramillo-López, P F; Ramírez, M I; Pérez-Salicrup, D R
2015-03-01
Community-based small-scale reforestation practices have been proposed as an alternative to low-efficiency massive reforestations conducted by external agents. These latter conventional reforestations are often carried out in soils that have been seriously degraded and this has indirectly contributed to the introduction of non-native species and/or acceptance of very low seedling survival rates. Bokashi is a fermented soil organic amendment that can be made from almost any available agricultural byproduct, and its beneficial effects in agriculture have been reported in various contexts. Here, we report the results of a community-based small-scale experimental reforestation where the provenance of pine seedlings (local and commercial) and the use of Bokashi as a soil amendment were evaluated. Bokashi was prepared locally by members of a small rural community in central Mexico. Almost two years after the establishment of the trial, survival rates for the unamended and amended local trees were 97-100% while survival of the commercial trees from unamended and amended treatments were 87-93%. Consistently through time, local and commercial seedlings planted in Bokashi-amended soils were significantly taller (x̅ = 152 cm) than those planted in unamended soils (̅x = 86 cm). An unplanned infection by Cronartium quercuum in the first year of the experiment was considered as a covariable. Infected seedlings showed malformations but this did not affect survival and growth rates. Bokashi amendment seems as an inexpensive, locally viable technology to increase seedling survival and growth and to help recover deforested areas where soils have been degraded. This allows local stakeholders to see more rapid results while helping them to maintain their interest in conservation activities. Copyright © 2014 Elsevier Ltd. All rights reserved.
Longevity of anterior resin-bonded bridges: survival rates of two tooth preparation designs.
Abuzar, M; Locke, J; Burt, G; Clausen, G; Escobar, K
2018-04-16
Significant developments have occurred in the design of resin-bonded bridges (RBB) over the past two decades. They are commonly used as an alternative treatment option for a single missing tooth. The longevity of these bridges needs to be further investigated to evaluate long-term outcomes for this option to remain relevant. A cohort of patients who received anterior resin-bonded bridges (ARBB) over two decades was studied retrospectively. Longevity of 206 ARBB was assessed using Kaplan-Meier probability estimates. The two modified tooth preparation designs investigated were: (A) mesial and distal vertical grooves only; and (B) one proximal groove adjacent to the pontic and two palatal grooves. Age and gender of the patient cohort were also recorded. Overall survival rate of ARBB was 98% at 5 years, 97.2% at 10 years, and 95.1% from 12 years till 21 years. Survival curves showed minor differences when compared for the two designs, age groups and gender of ARBB recipients. Differences in the proportion of surviving bridges for design A (95.96%) and design B (98.13%) were not statistically significant (Fisher's exact test). Anterior RBB with described tooth preparation designs demonstrate a high survival rate. © 2018 Australian Dental Association.
Daily survival rate and habitat characteristics of nests of Wilson's Plover
Zinsser, Elizabeth; Sanders, Felicia J.; Gerard, Patrick D.; Jodice, Patrick G.R.
2017-01-01
We assessed habitat characteristics and measured daily survival rate of 72 nests of Charadrius wilsonia (Wilson's Plover) during 2012 and 2013 on South Island and Sand Island on the central coast of South Carolina. At both study areas, nest sites were located at slightly higher elevations (i.e., small platforms of sand) relative to randomly selected nearby unused sites, and nests at each study area also appeared to be situated to enhance crypsis and/or vigilance. Daily survival rate (DSR) of nests ranged from 0.969 to 0.988 among study sites and years, and the probability of nest survival ranged from 0.405 to 0.764. Flooding and predation were the most common causes of nest failure at both sites. At South Island, DSR was most strongly related to maximum tide height, which suggests that flooding and overwash may be common causes of nest loss for Wilson's Plovers at these study sites. The difference in model results between the 2 nearby study sites may be partially due to more-frequent flooding at Sand Island because of some underlying yet unmeasured physiographic feature. Remaining data gaps for the species include regional assessments of nest and chick survival and habitat requirements during chick rearing.
Annual survival rates of adult and immature eastern population tundra swans
Nichols, J.D.; Bart, J.; Limpert, R.J.; Sladen, William J. L.; Hines, J.E.
1992-01-01
Tundra swans (Cygnus columbianus ) of the eastern population were neckbanded in Maryland, North Carolina, and Alaska from 1966 through 1990. These swans were resighted and recaptured during autumn, winter, and spring, 1966-1990. Although the original motivation for this study involved swan movements, we wanted to use the resulting data to test hypotheses about sources of variation in swan survival rates. Recaptures of legbanded and neckbanded swans permitted us to estimate neckband loss rates, which were found to vary with age and sex of swans, and number of years since initial application. Estimates of annual neckband retention rate ranged from about 0.50 for adult male swans greater than or equal to 2 years after initial neckbanding to > 0.96 for immature swans and adult females the first year following neckbanding. This variation in neckband loss rates prevented the simple correction of survival estimates to account for such loss. Consequently, we developed a series of multinomial models parameterized with survival, sighting, and neckband retention probabilities for use with the recapture and resighting data.
Survival and reproductive rate of mites in relation to resistance of their barn swallow hosts.
Møller, A P
2000-08-01
Parasite resistance may act via a number of different mechanisms that regulate or control the survival and the reproductive rate of parasites. Observations and experiments were used to test for effects of host resistance on parasite survival and rate of reproduction. Natural levels of infestation of barn swallow Hirundo rustica nests by the tropical fowl mite Ornithonyssus bursa were positively related to brood size, inversely related to the length of the outermost tail feathers of male nest owners (a secondary sexual character) and affected by time of reproduction by the host. A mite inoculation experiment, in which 50 adult mites were introduced into nests during the laying period of the host, was used to test for differential survival and reproduction of mites as a function of host resistance. The relationship between survival and reproduction of parasites, male tail length and host resistance was investigated. There was a negative relationship between mite numbers per nest after fledging of nestlings and male tail length. This relationship was mainly caused by a reduction in the number of mites in the first and second nymph stage with increasing tail length of male hosts, implying a reduction in rate of reproduction of mites. The proportion of mites that had recently fed was inversely related to tail length of male hosts. The proportion of nymph stages was positively related to the proportion of mites that had recently had a blood meal. Parasite resistance of barn swallows to the tropical fowl mite thus appeared to act through increased mortality rate of adult and nymph stages of mites, and through reduced reproductive rates of mites on resistant hosts. This is the first study demonstating a direct relationship between fitness components of a parasite and the expression of a secondary sexual character of a host.
Laugerman, Marcia; Shelley, Mack; Rover, Diane; Mickelson, Steve
2015-01-01
This study uses a unique synthesized set of data for community college students transferring to engineering by combining several cohorts of longitudinal data along with transcript-level data, from both the Community College and the University, to measure success rates in engineering. The success rates are calculated by developing Kaplan-Meier…
Audit Calculations of LBLOCA for Ulchin Unit 1 and 2 Power Up rate
Energy Technology Data Exchange (ETDEWEB)
Kang, Donggu; Huh, Byunggil; Yoo, Seunghunl; Yang, Chaeyong; Seul, Kwangwon [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)
2013-05-15
The KINS-Realistic Evaluation Model (KINS-REM) was developed for the independent audit calculation in 1991, and the code accuracy and statistical method have been improved. To support the licensing review and to confirm the validity of licensee's calculation, regulatory auditing calculations have been also conducted. Currently, the modification of Ulchin 1 and 2 operating license for 4.5% power up rate is under review. In this study, the regulatory audit calculation for LBLOCA of Ulchin Unit 1 and 2 with 4.5% power up rate was performed by applying KINS-REM. In this study, the regulatory audit calculation for LBLOCA of Ulchin Unit 1 and 2 with 4.5% power up rate was performed by applying KINS-REM. It is confirmed that the analysis results of LBLOCA for Ulchin 1 and 2 power up rate meets the PCT acceptance criteria.
Sakamoto, Y
2002-01-01
In the prevention of nuclear disaster, there needs the information on the dose equivalent rate distribution inside and outside the site, and energy spectra. The three dimensional radiation transport calculation code is a useful tool for the site specific detailed analysis with the consideration of facility structures. It is important in the prediction of individual doses in the future countermeasure that the reliability of the evaluation methods of dose equivalent rate distribution and energy spectra by using of Monte Carlo radiation transport calculation code, and the factors which influence the dose equivalent rate distribution outside the site are confirmed. The reliability of radiation transport calculation code and the influence factors of dose equivalent rate distribution were examined through the analyses of critical accident at JCO's uranium processing plant occurred on September 30, 1999. The radiation transport calculations including the burn-up calculations were done by using of the structural info...
Dadaci, Mehmet; Ince, Bilsev; Altuntas, Zeynep; Bitik, Ozan; Kamburoglu, Haldun Onuralp; Uzun, Hakan
2016-01-01
The fingertip is the most frequently injured and amputated segment of the hand. There are controversies about defining clear indications for microsurgical replantation. Many classification systems have been proposed to solve this problem. No previous study has simultaneously correlated different classification systems with replant survival rate. The aim of the study is to compare the outcomes of fingertip replantations according to Tamai and Yamano classifications. 34 consecutive patients who underwent fingertip replantation between 2007 and 2014 were retrospectively reviewed with respect to the Tamai and Yamano classifications. The medical charts from record room were reviewed. The mean age of the patients was 36.2 years. There were 30 men and 4 women. All the injuries were complete amputations. Of the 34 fingertip amputations, 19 were in Tamai zone 2 and 15 were in Tamai zone 1. When all the amputations were grouped in reference to the Yamano classification, 6 were type 1 guillotine, 8 were type 2 crush and 20 were type 3 crush avulsions. Of the 34 fingertips, 26 (76.4%) survived. Ten (66.6%) of 15 digits replanted in Tamai zone 1 and 16 (84.2%) of 19 digits replanted in Tamai zone 2 survived. There were no replantation failures in Yamano type 1 injuries (100%) and only two failed in Yamano type 2 (75%). Replantation was successful in 14 of 20 Yamano type 3 injuries, but six failed (70%). The percentage of success rates was the least in the hybridized groups of Tamai zone 1-Yamano type 2 and Tamai zone 1-Yamano type 3. Although clinically distinct, the survival rates between the groups were not statistically significantly different. The level and mechanism of injury play a decisive role in the success of fingertip replantation. Success rate increases in proximal fingertip amputations without crush injury.
Directory of Open Access Journals (Sweden)
Mehmet Dadaci
2016-01-01
Full Text Available Background: The fingertip is the most frequently injured and amputated segment of the hand. There are controversies about defining clear indications for microsurgical replantation. Many classification systems have been proposed to solve this problem. No previous study has simultaneously correlated different classification systems with replant survival rate. The aim of the study is to compare the outcomes of fingertip replantations according to Tamai and Yamano classifications. Materials and Methods: 34 consecutive patients who underwent fingertip replantation between 2007 and 2014 were retrospectively reviewed with respect to the Tamai and Yamano classifications. The medical charts from record room were reviewed. The mean age of the patients was 36.2 years. There were 30 men and 4 women. All the injuries were complete amputations. Of the 34 fingertip amputations, 19 were in Tamai zone 2 and 15 were in Tamai zone 1. When all the amputations were grouped in reference to the Yamano classification, 6 were type 1 guillotine, 8 were type 2 crush and 20 were type 3 crush avulsions. Results: Of the 34 fingertips, 26 (76.4% survived. Ten (66.6% of 15 digits replanted in Tamai zone 1 and 16 (84.2% of 19 digits replanted in Tamai zone 2 survived. There were no replantation failures in Yamano type 1 injuries (100% and only two failed in Yamano type 2 (75%. Replantation was successful in 14 of 20 Yamano type 3 injuries, but six failed (70%. The percentage of success rates was the least in the hybridized groups of Tamai zone 1-Yamano type 2 and Tamai zone 1-Yamano type 3. Although clinically distinct, the survival rates between the groups were not statistically significantly different. Conclusions: The level and mechanism of injury play a decisive role in the success of fingertip replantation. Success rate increases in proximal fingertip amputations without crush injury.
Mehmet Dadaci; Bilsev Ince; Zeynep Altuntas; Ozan Bitik; Haldun Onuralp Kamburoglu; Hakan Uzun
2016-01-01
Background: The fingertip is the most frequently injured and amputated segment of the hand. There are controversies about defining clear indications for microsurgical replantation. Many classification systems have been proposed to solve this problem. No previous study has simultaneously correlated different classification systems with replant survival rate. The aim of the study is to compare the outcomes of fingertip replantations according to Tamai and Yamano classifications. Materials a...
Retrospective analysis of survival rates and marginal bone loss on short implants in the mandible.
Draenert, Florian G; Sagheb, Keyvan; Baumgardt, Katharina; Kämmerer, Peer W
2012-09-01
Short implants have become an interesting alternative to bone augmentation in dental implantology. Design of shorter implants and longer surveillance times are a current research issue. The goal of this study was to show the survival rates of short implants below 9 mm in the partly edentulous mandibular premolar and molar regions with fixed prosthetics. Marginal vertical and 2D bone loss was evaluated additionally. Different implant designs are orientationally evaluated. A total of 247 dental implants with fixed prosthetics (crowns and bridges) in the premolar and molar region of the mandible were evaluated; 47 implants were 9 mm or shorter. Patient data were evaluated to acquire implant survival rates, implant diameter, gender and age. Panoramic X-rays were analysed for marginal bone loss. Average surveillance time was 1327 days. Cumulative survival rate (CSR) of short implants was 98% (1 implants lost) compared to 94% in the longer implants group without significance. Thirty-five of the short implants were Astratech (0 losses) and 12 were Camlog Screw Line Promote Plus (1 loss). Early vertical and two-dimensional marginal bone loss was not significantly different in short and regular length implant group with an average of 0.6 mm and 0.7 mm(2) in short implants over the observation period. Within the limitations of this study, we conclude that short implants with a length of 9 mm or less have equal survival rates compared with longer implants over the observation period of 1-3 years. © 2011 John Wiley & Sons A/S.
Directory of Open Access Journals (Sweden)
Chris Bambey Guure
2012-01-01
Full Text Available The survival function of the Weibull distribution determines the probability that a unit or an individual will survive beyond a certain specified time while the failure rate is the rate at which a randomly selected individual known to be alive at time will die at time (. The classical approach for estimating the survival function and the failure rate is the maximum likelihood method. In this study, we strive to determine the best method, by comparing the classical maximum likelihood against the Bayesian estimators using an informative prior and a proposed data-dependent prior known as generalised noninformative prior. The Bayesian estimation is considered under three loss functions. Due to the complexity in dealing with the integrals using the Bayesian estimator, Lindley’s approximation procedure is employed to reduce the ratio of the integrals. For the purpose of comparison, the mean squared error (MSE and the absolute bias are obtained. This study is conducted via simulation by utilising different sample sizes. We observed from the study that the generalised prior we assumed performed better than the others under linear exponential loss function with respect to MSE and under general entropy loss function with respect to absolute bias.
Directory of Open Access Journals (Sweden)
Ceyda Ozçakır Tomruk
2016-01-01
Full Text Available The aim of this study was to assess the prevalence of sinus-lifting procedures and survival rates of implants placed in the posterior maxilla. This retrospective chart review examined consecutive patients with tooth/teeth loss in the posterior maxilla between 2008 and 2012 treated with sinus lift, when needed, and implant insertion. Demographic variables, health status, residual alveolar bone height, augmentation types, the implant position, diameter and height, and implant failure, prosthesis types, and the marginal bone loss were recorded. The study included 302 patients at a mean age of 5.2 years, who received a total of 609 dental implants. A total of 380 (62.3% implants were inserted in native areas, 203 (33.3% ones in external sinus-lifted areas and 26 (4.4% ones in internal lifted areas. The survival rate in native or internal lifted areas were 100% and 95.6% in external sinus lifted ones (10 implant failures/203 implants. Almost half of the implants were examined radiologically with a mean duration of 30 months and the mean marginal bone loss was 0.64 ± 1.2 mm. The results showed that the survival rates of native bone and the internal sinus lifting were slightly higher than that of external sinus lifting. Implants placed with sinus augmentation exhibited more marginal bone loss than implants in native bone.
Weiser, Emily L.; Lanctot, Richard B.; Brown, Stephen C.; Gates, H. River; Bentzen, Rebecca L.; Bêty, Joël; Boldenow, Megan L.; English, Willow B.; Franks, Samantha E.; Koloski, Laura; Kwon, Eunbi; Lamarre, Jean-Francois; Lank, David B.; Liebezeit, Joseph R.; McKinnon, Laura; Nol, Erica; Rausch, Jennie; Saalfeld, Sarah T.; Senner, Nathan R.; Ward, David H.; Woodard, Paul F.; Sandercock, Brett K.
2018-01-01
Many Arctic shorebird populations are declining, and quantifying adult survival and the effects of anthropogenic factors is a crucial step toward a better understanding of population dynamics. We used a recently developed, spatially explicit Cormack–Jolly–Seber model in a Bayesian framework to obtain broad-scale estimates of true annual survival rates for 6 species of shorebirds at 9 breeding sites across the North American Arctic in 2010–2014. We tested for effects of environmental and ecological variables, study site, nest fate, and sex on annual survival rates of each species in the spatially explicit framework, which allowed us to distinguish between effects of variables on site fidelity versus true survival. Our spatially explicit analysis produced estimates of true survival rates that were substantially higher than previously published estimates of apparent survival for most species, ranging from S = 0.72 to 0.98 across 5 species. However, survival was lower for the arcticolasubspecies of Dunlin (Calidris alpina arcticola; S = 0.54), our only study taxon that migrates through the East Asian–Australasian Flyway. Like other species that use that flyway, arcticola Dunlin could be experiencing unsustainably low survival rates as a result of loss of migratory stopover habitat. Survival rates of our study species were not affected by timing of snowmelt or summer temperature, and only 2 species showed minor variation among study sites. Furthermore, although previous reproductive success, predator abundance, and the availability of alternative prey each affected survival of one species, no factors broadly affected survival across species. Overall, our findings of few effects of environmental or ecological variables suggest that annual survival rates of adult shorebirds are generally robust to conditions at Arctic breeding sites. Instead, conditions at migratory stopovers or overwintering sites might be driving adult survival rates and should be the
Papaspyridakos, Panos; Mokti, Muizzaddin; Chen, Chun-Jung; Benic, Goran I; Gallucci, German O; Chronopoulos, Vasilios
2014-10-01
The treatment of mandibular edentulism with implant fixed complete dental prostheses (IFCDPs) is a routinely used treatment option. The study aims to report the implant and prosthodontic survival rates associated with IFCDPs for the edentulous mandible after an observation period of a minimum 5 years. An electronic MEDLINE/PubMED search was conducted to identify randomized controlled clinical trials and prospective studies with IFCDPs for the edentulous mandible. Clinical studies with at least 5-year follow-up were selected. Pooled data were statistically analyzed and cumulative implant- and prosthesis survival rates were calculated by meta-analysis, regression, and chi-square statistics. Implant-related and prosthesis-related factors were identified and their impact on survival rates was assessed. Seventeen prospective studies, including 501 patients and 2,827 implants, were selected for meta-analysis. The majority of the implants (88.5% of all placed implants) had been placed in the interforaminal area. Cumulative implant survival rates for rough surface ranged from 98.42% (95% confidence interval [CI]: 97.98-98.86) (5 years) to 96.86% (95% CI: 96.00-97.73) (10 years); smooth surface implant survival rates ranged from 98.93% (95% CI: 98.38-99.49) (5 years) to 97.88% (95% CI: 96.78-98.98) (10 years). The prosthodontic survival rates for 1-piece IFCDPs ranged from 98.61% (95% CI: 97.80-99.43) (5 years) to 97.25% (95% CI: 95.66-98.86) (10 years). Treatment with mandibular IFCDPs yields high implant and prosthodontic survival rates (more than 96% after 10 years). Rough surface implants exhibited cumulative survival rates similar to the smooth surface ones (p > .05) in the edentulous mandible. The number of supporting implants and the antero-posterior implant distribution had no influence (p > .05) on the implant survival rate. The prosthetic design and veneering material, the retention type, and the loading protocol (delayed, early, and immediate) had no
FABGEN, a transient power-generation and isotope birth rate calculator
International Nuclear Information System (INIS)
Roland, H.C.
1975-04-01
A description is given of the FABGEN program, a fast-running program for calculating fuel element power-generation rates and selected fission product birth rates in a known neutron flux as functions of time. A first forward difference calculation is used, and the time step is one day. Provisions are made for including various fuel element lengths, variation of thermal flux with time, and use of different fertile isotopes. Five different fission products may be specified for birth-rate calculations. A daily summary may be output, or totals by days may be accumulated for final output. (U.S.)
Energy Technology Data Exchange (ETDEWEB)
El-Maaref, A.A., E-mail: ahmed.maaref@azhar.edu.eg; Saddeek, Y.B.; Abou halaka, M.M.
2017-02-15
Highlights: • Fine-structure calculations of sulfurlike Mn have been performed using configuration interaction technique, CI. • The relativistic effects, Breit-Pauli Hameltonian, have been correlated to the CI calculations. • Excitation rates by electron impact of the Mn X ion have been evaluated up to ionization potential. - Abstract: Fine-structure calculations of energies and transition parameters have been performed using the configuration interaction technique (CI) as implemented in CIV3 code for sulfurlike manganese, Mn X. The calculations are executed in an intermediate coupling scheme using the Breit-Pauli Hamiltonian. As well as, energy levels and oscillator strengths are calculated using LANL code, where the calculations by LANL have been used to estimate the accuracy of the present CI calculations. The calculated energy levels, oscillator strengths, and lifetimes are in reasonable agreement with the published experimental and theoretical values. Electron impact excitation rates of the transitions emit soft X-ray and extreme ultraviolet (EUV) wavelengths have been evaluated. The level population densities are calculated using the collisional radiative model (CRM), as well. The collisional excitation rates and collision strengths have been calculated in the electron temperature range ≤ the ionization potential, ∼1–250 eV.
International Nuclear Information System (INIS)
Saur, H.B.; Lerch, H.; Schober, O.
1996-01-01
Results of survival rates in differentiated thyroid carcinoma and comparison with a review of literature are given. Four hundred and sixty-four patients with differentiated cancer of the thyroid (354 female, 110 male, range: 6 to 84 years, median: 46.8 years; 275 patients with papillary and 190 with follicular cancer) were analyzed retrospectively. All patients were treated with ablative doses of radioiodine after thyroidectomy including compartment oriented lymphadenectomy in 27 patients. All patients passed an individual systematic follow-up according to risk: 'Low risk' pT≤3NxM0 vs. 'high risk' pT4 and/or M1. Early postoperative radiation was not included even in patients with local invasion (pT4). The corrected 5- and 10-year survival rates for papillary cancer are 0.91 and 0.91, for follicular cancer 0.94 resp. 0.78 (p=0.55), age (≤40 years 0.96 and 0.96, >40 years 0.90 and 0.80; p=0.008), gender (female 0.93 and 0.92, male 0.90 and 0.70; p=0.06) and invasion/distant metastases (pT4 and/or M1 0.83 and 0.71, other 0.97 and 0.97; p=0.0001). A systematic follow-up with an individually adapted standardized scheme is associated with high survival rates in patients with differentiated cancer of the thyroid. Early diagnosis of recurrences, locoregional lymph node and distant metastases with early surgical treatment including compartment oriented lymphadenectomy and radioiodine therapy yield high survival even without external radiation. (orig./MG) [de
2011-04-12
... consistently the term ``regular hours.'' The term ``regular hours'' refers to the hours during regular working... during non-overtime and non-holiday hours of operation. Official establishments and official egg products.... FSIS developed proposed formulas in consultation with a private accounting firm to determine the rates...
Nair, D. R.
2017-12-01
The purpose of this project was to determine the effect of two mutated oncogenes on the survival rate from invasive breast carcinoma when in comparison to the mutation of a single oncogene on the survival rate. An oncogene is defined as a gene, that when mutated, can lead to cancer. The two oncogenes used in this project were human epidermal growth factor receptor 2 (HER2) and c-myc (MYC). HER2 and MYC are both oncogenes that contribute to the formation of cancer. HER2 proteins are receptors on breast cells, and when the HER2 gene is mutated, there is an overexpression of HER2 protein on the breast cell. This makes the breast cells proliferate uncontrollably. MYC is a gene that codes for a transcription factor that plays a role in cell cycle progression. The overexpression of MYC also leads to the proliferation of cells. I hypothesized that if there is a mutation in both the MYC and HER2 genes, then the survival rate of invasive breast carcinoma patients will be lower compared to patients with the mutations of only MYC or HER2. To test this hypothesis, we conducted individual gene searches in CBioPortal for HER2 in the datasets from the studies titled TCGA Nature 2012, TCGA Cell 2015, and TCGA Provisional. We conducted individual gene searches in CBioPortal for MYC in the same datasets. The survival rate data was then exported and analyzed for patients with mutations of either HER2 or MYC and with mutations of both genes. To determine the cases that had both HER2 and MYC mutations, we found the overlapping cases in both HER2 and MYC groups for all three datasets. We calculated the median of the survival data for cases where either HER2 or MYC was mutated and cases where both MYC and HER2 were mutated. From the first dataset, the median of MYC data was 95.53, HER2 data was 95.83, and both HER2 and MYC data was 91.24. In the second dataset, the median of MYC data was 92.17 , HER2 data was 93.5, and both HER2 and MYC data was 87.95 . In the third dataset, the median
It isn't like this on TV: Revisiting CPR survival rates depicted on popular TV shows.
Portanova, Jaclyn; Irvine, Krystle; Yi, Jae Yoon; Enguidanos, Susan
2015-11-01
Public perceptions of cardiopulmonary resuscitation (CPR) can be influenced by the media. Nearly two decades ago, a study found that the rates of survival following CPR were far higher in popular TV shows than actual rates. In recent years, major strides toward enhanced education and communication around life sustaining interventions have been made. This study aimed to reassess the accuracy of CPR portrayed by popular medical TV shows. Additionally, we sought to determine whether these shows depicted discussions of care preferences and referenced advance directives. Three trained research assistants independently coded two leading medical dramas airing between 2010 and 2011, Grey's Anatomy and House. Patient characteristics, CPR survival rates, and goals of care discussions were recorded. CPR was depicted 46 times in the 91 episodes, with a survival rate of 69.6%. Among those immediately surviving following CPR, the majority (71.9%) survived to hospital discharge and 15.6% died before discharge. Advance directive discussions only occurred for two patients, and preferences regarding code status (8.7%), intubation (6.5%) and feeding (4.3%) rarely occurred. Both popular TV shows portrayed CPR as more effective than actual rates. Overall, the shows portrayed an immediate survival rate nearly twice that of actual survival rates. Inaccurate TV portrayal of CPR survival rates may misinform viewers and influence care decisions made during serious illness and at end of life. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
The influence of disturbance events on survival and dispersal rates of Florida box turtles
Dodd, C.K.; Ozgul, A.; Oli, M.K.
2006-01-01
Disturbances have the potential to cause long-term effects to ecosystem structure and function, and they may affect individual species in different ways. Long-lived vertebrates such as turtles may be at risk from such events, inasmuch as their life histories preclude rapid recovery should extensive mortality occur. We applied capture–mark–recapture models to assess disturbance effects on a population of Florida box turtles (Terrapene carolina bauri) on Egmont Key, Florida, USA. Near the midpoint of the study, a series of physical disturbances affected the island, from salt water overwash associated with several tropical storms to extensive removal of nonindigenous vegetation. These disturbances allowed us to examine demographic responses of the turtle population and to determine if they affected dispersal throughout the island. Adult survival rates did not vary significantly either between sexes or among years of the study. Survival rates did not vary significantly between juvenile and adult turtles, or among years of the study. Furthermore, neither adult nor juvenile survival rates differed significantly between pre- and post-disturbance. However, dispersal rates varied significantly among the four major study sites, and dispersal rates were higher during the pre-disturbance sampling periods compared to post-disturbance. Our results suggest few long-term effects on the demography of the turtle population. Florida box turtles responded to tropical storms and vegetation control by moving to favorable habitats minimally affected by the disturbances and remaining there. As long as turtles and perhaps other long-lived vertebrates can disperse to non-disturbed habitat, and high levels of mortality do not occur in a population, a long life span may allow them to wait out the impact of disturbance with potentially little effect on long-term population processes.
Relativistic quasiparticle random-phase approximation calculation of total muon capture rates
International Nuclear Information System (INIS)
Marketin, T.; Paar, N.; Niksic, T.; Vretenar, D.
2009-01-01
The relativistic proton-neutron quasiparticle random phase approximation (pn-RQRPA) is applied in the calculation of total muon capture rates on a large set of nuclei from 12 C to 244 Pu, for which experimental values are available. The microscopic theoretical framework is based on the relativistic Hartree-Bogoliubov (RHB) model for the nuclear ground state, and transitions to excited states are calculated using the pn-RQRPA. The calculation is fully consistent, i.e., the same interactions are used both in the RHB equations that determine the quasiparticle basis, and in the matrix equations of the pn-RQRPA. The calculated capture rates are sensitive to the in-medium quenching of the axial-vector coupling constant. By reducing this constant from its free-nucleon value g A =1.262 by 10% for all multipole transitions, the calculation reproduces the experimental muon capture rates to better than 10% accuracy.
Directory of Open Access Journals (Sweden)
R. Belabbas
2016-12-01
Full Text Available A higher litter size at birth has been reported in female rabbits from a Synthetic line than in those of the Local Algerian population. The aim of this work was to analyse whether this difference in litter size was due to a higher ovulation rate and/or embryonic survival rate in Synthetic line than in Local Algerian population. In total, 24 multiparous female rabbits from Synthetic line and 23 from Local population were used in this experiment. Litter size at birth was recorded up to the first 3 parities. Litter size was 20% higher in Synthetic line than Local population. At their 4th gestation, the females were euthanized at 72 h post coitum. Synthetic line females had 50% more ova and embryos than those of Local population (+4.42 ova and +3.92 embryos, respectively. Synthetic line displayed a lower percentage of normal embryos and a larger number of unfertilized oocytes than Local population (–2.81% and +0.64 oocytes, respectively, but differences were not relevant. Synthetic line showed a lesser embryonic stage of development at 72 h post coitum, showing a higher percentage of early morulae (31.50 vs. 8.50% and a lower percentage of compact morulae (51.45 vs. 78.65% than Local population. No relevant difference was found for early embryonic survival rate between Synthetic line and Local population. In conclusion, the difference in litter size was mainly due to a higher ovulation rate in the Synthetic line, allowing more embryos to develop in this line.
Energy Technology Data Exchange (ETDEWEB)
Shapiro, A; Lin, B I [Cincinnati Univ., Ohio (USA). Dept. of Chemical and Nuclear Engineering; Windham, J P; Kereiakes, J G
1976-07-01
..gamma.. flux density and dose rate distributions have been calculated about implantable californium-252 sources for an infinite tissue medium. Point source flux densities as a function of energy and position were obtained from a discrete-ordinates calculation, and the flux densities were multiplied by their corresponding kerma factors and added to obtain point source dose rates. The point dose rates were integrated over the line source to obtain line dose rates. Container attenuation was accounted for by evaluating the point dose rate as a function of platinum thickness. Both primary and secondary flux densities and dose rates are presented. The agreement with an independent Monte Carlo calculation was excellent. The data presented should be useful for the design of new source configurations.
Suksaphar, Warattama; Banomyong, Danuchit; Jirathanyanatt, Titalee; Ngoenwiwatkul, Yaowaluk
2018-02-01
The aim of the present study was to compare the survival rates against fracture of premolar endodontically treated teeth (ETT) restored with resin composite or crowns and to identify risk factors associated with the fracture. Data from dental records and radiographs of premolar ETT with postendodontic restorations (ie, resin composite or crowns) were collected between 2012 and 2016 and selected following selected inclusion and exclusion criteria. Tooth location, type of restoration, number of proximal contacts, and amount of tooth surface loss were recorded. The incidence and restorability of postendodontic fractures were identified. Survival rates against fracture of the 2 restoration types were calculated using Kaplan-Meier survival analysis. Any potential factors associated with fractures were identified using Cox proportional hazards models. The survival rate against fracture of ETT restored with crowns (95.1%) was higher than resin composite (77.0%). ETT restored with resin composite with 1 or 2 tooth surface losses and 2 proximal contacts had a high survival rate of 88.5% that was not significantly different from ETT with crowns. A higher incidence of restorability after fracture was observed in teeth restored with resin composite than crowns. The type of restoration and number of proximal contacts were identified as potential risk factors associated with fracture incidence. The survival rate against fracture of ETT restored with crowns was higher than resin composite. However, ETT with 1 or 2 tooth surface losses and 2 proximal contacts and restored with resin composite showed a high survival rate that was comparable with ETT restored with crowns. Copyright © 2017 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
Modeling for Dose Rate Calculation of the External Exposure to Gamma Emitters in Soil
International Nuclear Information System (INIS)
Allam, K. A.; El-Mongy, S. A.; El-Tahawy, M. S.; Mohsen, M. A.
2004-01-01
Based on the model proposed and developed in Ph.D thesis of the first author of this work, the dose rate conversion factors (absorbed dose rate in air per specific activity of soil in nGy.hr - 1 per Bq.kg - 1) are calculated 1 m above the ground for photon emitters of natural radionuclides uniformly distributed in the soil. This new and simple dose rate calculation software was used for calculation of the dose rate in air 1 m above the ground. Then the results were compared with those obtained by five different groups. Although the developed model is extremely simple, the obtained results of calculations, based on this model, show excellent agreement with those obtained by the above-mentioned models specially that one adopted by UNSCEAR. (authors)
Distorted wave approach to calculate Auger transition rates of ions in metals
Energy Technology Data Exchange (ETDEWEB)
Deutscher, Stefan A. E-mail: sad@utk.edu; Diez Muino, R.; Arnau, A.; Salin, A.; Zaremba, E
2001-08-01
We evaluate the role of target distortion in the determination of Auger transition rates for multicharged ions in metals. The required two electron matrix elements are calculated using numerical solutions of the Kohn-Sham equations for both the bound and continuum states. Comparisons with calculations performed using plane waves and hydrogenic orbitals are presented.
International Nuclear Information System (INIS)
Quade, U.
1994-01-01
Neutron- und Gamma dose rate calculations were performed for the storage containers filled with plutonium nitrate of the MOX fabrication facility of Siemens. For the particle transport calculations the Monte Carlo Code MCNP 4.2 was used. The calculated results were compared with experimental dose rate measurements. It can be stated that the choice of the code system was appropriate since all aspects of the many facettes of the problem were well reproduced in the calculations. The position dependency as well as the influence of the shieldings, the reflections and the mutual influences of the sources were well described by the calculations for the gamma and for the neutron dose rates. However, good agreement with the experimental results on the gamma dose rates could only be reached when the lead shielding of the detector was integrated into the geometry modelling of the calculations. For some few cases of thick shieldings and soft gamma ray sources the statistics of the calculational results were not sufficient. In such cases more elaborate variance reduction methods must be applied in future calculations. Thus the MCNP code in connection with NGSRC has been proven as an effective tool for the solution of this type of problems. (orig./HP) [de
A modified Gaussian integration method for thermal reaction rate calculation in U- and Pu-isotopes
International Nuclear Information System (INIS)
Bosevski, T.; Fredin, B.
1966-01-01
An advanced multi-group cell calculations a lot of data information is very often necessary, and hence the data administration will be elaborate, and the spectrum calculation will be time consuming. We think it is possible to reduce the necessary data information by using an effective reaction rate integration method well suited for U- and Pu-absorptions (author)
THIDA: code system for calculation of the exposure dose rate around a fusion device
International Nuclear Information System (INIS)
Iida, Hiromasa; Igarashi, Masahito.
1978-12-01
A code system THIDA has been developed for calculation of the exposure dose rates around a fusion device. It consists of the following: one- and two-dimensional discrete ordinate transport codes; induced activity calculation code; activation chain, activation cross section, radionuclide gamma-ray energy/intensity and gamma-ray group constant files; and gamma ray flux to exposure dose rate conversion coefficients. (author)
The correlation schemes in calculations of the rate constants of some radiation chemical reactions
International Nuclear Information System (INIS)
Zagorets, P.A.; Shostenko, A.G.; Kim, V.
1983-01-01
The various correlation relationships of the evaluation of the rate constants of radiation chemical reactions of addition, abstraction and isomerization were considered. It was shown that neglection of the influence of solvent can result in errors in calculations of rate constants equalling two orders in magnitude. Several examples of isokinetic relationship are given. The methods of calculation of transmission coefficient of reaction addition have been discussed. (author)
Yamazaki, Hiroki; Lai, Yu-Chang; Tateno, Morihiro; Setoguchi, Asuka; Goto-Koshino, Yuko; Endo, Yasuyuki; Nakaichi, Munekazu; Tsujimoto, Hajime; Miura, Naoki
2017-01-01
We tested the hypotheses that hypoxic stimulation enhances growth potentials of canine lymphoma cells by activating hypoxia-inducible factor 1α (HIF-1α), and that the hypoxia-activated prodrug (TH-302) inhibits growth potentials in the cells. We investigated how hypoxic culture affects the growth rate, chemoresistance, and invasiveness of canine lymphoma cells and doxorubicin (DOX)-resistant lymphoma cells, and influences of TH-302 on survival rate of the cells under hypoxic conditions. Our results demonstrated that hypoxic culture upregulated the expression of HIF-1α and its target genes, including ATP-binding cassette transporter B1 (ABCB1), ATP-binding cassette transporter G2 (ABCG2), platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), and survivin, and enhanced the growth rate, DOX resistance, and invasiveness of the cells. Additionally, TH-302 decreased the survival rate of the cells under hypoxic condition. Our studies suggest that hypoxic stimulation may advance the tumorigenicity of canine lymphoma cells, favoring malignant transformation. Therefore, the data presented may contribute to the development of TH-302-based hypoxia-targeting therapies for canine lymphoma.
Moustakas, Aristides; Evans, Matthew R
2015-02-28
Plant survival is a key factor in forest dynamics and survival probabilities often vary across life stages. Studies specifically aimed at assessing tree survival are unusual and so data initially designed for other purposes often need to be used; such data are more likely to contain errors than data collected for this specific purpose. We investigate the survival rates of ten tree species in a dataset designed to monitor growth rates. As some individuals were not included in the census at some time points we use capture-mark-recapture methods both to allow us to account for missing individuals, and to estimate relocation probabilities. Growth rates, size, and light availability were included as covariates in the model predicting survival rates. The study demonstrates that tree mortality is best described as constant between years and size-dependent at early life stages and size independent at later life stages for most species of UK hardwood. We have demonstrated that even with a twenty-year dataset it is possible to discern variability both between individuals and between species. Our work illustrates the potential utility of the method applied here for calculating plant population dynamics parameters in time replicated datasets with small sample sizes and missing individuals without any loss of sample size, and including explanatory covariates.
A calculation of the surface recombination rate constant for hydrogen isotopes on metals
International Nuclear Information System (INIS)
Baskes, M.J.
1980-01-01
The surface recombination rate constant for hydrogen isotopes on a metal has been calculated using a simple model whose parameters may be determined by direct experimental measurements. Using the experimental values for hydrogen diffusivity, solubility, and sticking coefficient at zero surface coverage a reasonable prediction of the surface recombination constant may be made. The calculated recombination constant is in excellent agreement with experiment for bcc iron. A heuristic argument is developed which, along with the rate constant calculation, shows that surface recombination is important in those metals in which hydrogen has an exothermic heat of solution. (orig.)
International Nuclear Information System (INIS)
Sunder, S.; Shoesmith, D.W.; Kolar, M.; Leneveu, D.M.
1998-01-01
Calculation of used nuclear fuel dissolution rates in a geological disposal vault requires a knowledge of the redox conditions in the vault. For redox conditions less oxidizing than those causing UO 2 oxidation to the U 3 O 7 , stage, a thermodynamically-based model is appropriate. For more oxidizing redox conditions a kinetic or an electrochemical model is needed to calculate these rates. The redox conditions in a disposal vault will be affected by the radiolysis of groundwater by the ionizing radiation associated with the fuel. Therefore, we have calculated the alpha-, beta- and gamma-dose rates in water in contact with the reference used fuel in the Canadian Nuclear Fuel Waste Management Program (CNFWMP) as a function of cooling time. Also, we have determined dissolution rates of UO 2 fuel as a function of alpha and gamma dose rates from our electrochemical measurements. These room-temperature rates are used to calculate the dissolution rates of used fuel at 100 o C, the highest temperature expected in a container in the CNFWMP, as a function of time since emplacement. It is shown that beta radiolysis of water will be the main cause of oxidation of used CANDU fuel in a failed container. The use of a kinetic or an electrochemical corrosion model, to calculate fuel dissolution rates, is required for a period of ∼1000 a following emplacement of copper containers in the geologic disposal vault envisaged in the CNFWMP. Beyond this time period a thermodynamically-based model adequately predicts the fuel dissolution rates. The results presented in this paper can be adopted to calculate used fuel dissolution rates for other used UO 2 fuels in other waste management programs. (author)
Reexamining the Dissolution of Spent Fuel: A Comparison of Different Methods for Calculating Rates
International Nuclear Information System (INIS)
Hanson, Brady D.; Stout, Ray B.
2004-01-01
Dissolution rates for spent fuel have typically been reported in terms of a rate normalized to the surface area of the specimen. Recent evidence has shown that neither the geometric surface area nor that measured with BET accurately predicts the effective surface area of spent fuel. Dissolution rates calculated from results obtained by flowthrough tests were reexamined comparing the cumulative releases and surface area normalized rates. While initial surface area is important for comparison of different rates, it appears that normalizing to the surface area introduces unnecessary uncertainty compared to using cumulative or fractional release rates. Discrepancies in past data analyses are mitigated using this alternative method
Directory of Open Access Journals (Sweden)
Nunak Nafiqoh
2011-12-01
Full Text Available This study examined the effect of two Lactobacillus bacteria on protease activity and growth rate of Litopenaeus vannamei. An experiment was conducted to examine protease activity and growth rate. The experiment consisted of two treatment tanks, the first tank was provided with artemia immersed in 2.6 x 1016 cfu/mL of bacteria solution, the second tank served as the control tank. After 20 days, the L. vannamei in the tank that received Lactobacillus have significantly different in growth, survival rate and protease activity (P<0.05 compared to the control, but no significant difference between Lactobacillus casei and Lactobacillus plantarum treatments. Within the digestive organ, protease activity of hepatopancreas and stomach demonstrated significant higher activity (P<0.05 compared to the intestine.
Calculation of nuclide inventory, decay power, activity and dose rates for spent nuclear fuel
International Nuclear Information System (INIS)
Haakansson, Rune
2000-03-01
The nuclide inventory was calculated for a BWR and a PWR fuel element, with burnups of 38 and 55 MWd/kg uranium for the BWR fuel, and 42 and 60 MWd/kg uranium for the PWR fuel. The calculations were performed for decay times of up to 300,000 years. Gamma and neutron dose rates have been calculated at a distance of 1 m from a bare fuel element and outside the spent fuel canister. The calculations were performed using the CASMO-4 code
HLW disposal by fission reactors; calculation of trans-mutation rate and recycle
International Nuclear Information System (INIS)
Mulyanto
1997-01-01
Transmutation of MA (Minor actinide) and LLFPS (long-lived fission products) into stable nuclide or short-lived isotopes by fission reactors seem to become an alternative technology for HLW disposal. in this study, transmutation rate and recycle calculation were developed in order to evaluate transmutation characteristics of MA and LLFPs in the fission reactors. inventory of MA and LLFPs in the transmutation reactors were determined by solving of criticality equation with 1-D cylindrical geometry of multigroup diffusion equations at the beginning of cycle (BOC). transmutation rate and burn-up was determined by solving of depletion equation. inventory of MA and LLFPs was calculated for 40 years recycle. From this study, it was concluded that characteristics of MA and LLFPs in the transmutation reactors can be evaluated by recycle calculation. by calculation of transmutation rate, performance of fission reactor for transmutation of MA or LLFPs can be discussed
Ruslim, S. K.; Purwoto, G.; Widyahening, I. S.; Ramli, I.
2017-08-01
To evaluate the characteristics and overall survival rates of early stage cervical cancer (FIGO IB-IIA) patients who receive definitive radiation therapy and those who are prescribed adjuvant postoperative radiation and to conduct a factors analysis of the variables that affect the overall survival rates in both groups of therapy. The medical records of 85 patients with cervical cancer FIGO stages IB-IIA who were treated at the Department of Radiotherapy of Cipto Mangunkusumo Hospital were reviewed and analyzed to determine their overall survival and the factors that affected it between a definitive radiation group and an adjuvant postoperative radiation group. There were 25 patients in the definitive radiation and 60 patients in the adjuvant radiation group. The overall survival rates in the adjuvant radiation group at years one, two, and three were 96.7%, 95%, and 93.3%, respectively. Negative lymph node metastasis had an average association with overall survival (p 12 g/dl was a factor with an average association with the overall survival (p cervical cancer FIGO stage IB-IIA patients who received definitive radiation or adjuvant postoperative radiation. Negative lymph node metastasis had an effect on the overall survival rate in the adjuvant postoperative radiation group, while a preradiation Hb level >12 g/dl tended to affect the overall survival in the definitive radiation group patients.
Preliminary calculations on the cooling rate of the Renca batholit, Sierra de San Luis, Argentina
International Nuclear Information System (INIS)
Lopez de Luchi, M.G.; Ostera, H.A.; Linares, E; Rosello, E.A
2001-01-01
Cooling rates can be used to constrain the unroofing history of plutonic-metamorphic system. Geocronological cooling rates (Spear and Parrish, 1996) can be unravelled using age calculations on minerals that were open systems and subsequently passed through their closure temperatures (Dodson, 1973) during cooling. Several age determinations on different minerals are needed in order to accurately constrain the cooling path of a pluton (Hodges 1991, Spear and Parrish, 1996 and references therein). Isotopic open-system behaviour in minerals can be modelled as volume diffusion process (Hodges, 1991 and references therein), which depends on the cooling rate of the whole system. We present the first results on the calculation of the cooling rate of the Renca batholith on the basis of the combination of both thermometric calculations and available crystallization and cooling ages (au)
Qureshi, Adnan I; Chughtai, Morad; Bah, Elhadj Ibrahima; Barry, Moumié; Béavogui, Kézély; Loua, Tokpagnan Oscar; Malik, Ahmed A
2015-02-01
Anecdotal reports suggesting that survival rates among hospitalized patients with Ebola virus disease in Guinea are higher than the 29.2% rate observed in the current epidemic in West Africa. Survival after symptom onset was determined using Kaplan Meier survival methods among patients with confirmed Ebola virus disease treated in Conakry, Guinea from March 25, 2014, to August 5, 2014. We analyzed the relationship between survival and patient factors, including demographics and clinical features. Of the 70 patients analyzed [mean age ± standard deviation (SD), 34 ± 14.1; 44 were men], 42 were discharged alive with a survival rate among hospitalized patients of 60% (95% confidence interval, 41.5-78.5%). The survival rate was 28 (71.8%) among 39 patients under 34 years of age, and 14 (46.7%) among 30 patients aged 35 years or greater (p = 0.034). The rates of myalgia (3 of 42 versus 7 of 28, p = 0.036) and hiccups (1 of 42 versus 5 of 28, p = 0.023) were significantly lower among patients who survived. Our results provide insights into a cohort of hospitalized patients with Ebola virus disease in whom survival is prominently higher than seen in other cohorts of hospitalized patients.
Basic survival needs and access to medicines--coming to grips with TRIPS: conversion + calculation.
Van Puymbroeck, Rudolf V
2010-01-01
"Access to medicines" is a broad concept. After a review of three authoritative frameworks that help to identify its constitutive components, this essay summarizes the actual situation on the ground in low- and middle-income countries on the basis of recent empirical work. An analysis of survey data from 36 countries concluded that developing countries should promote generic medicines as a key policy option for improving access to medicines. Taking an international perspective to that recommendation, this essay reviews the World Trade Organization's Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) and, particularly, how this agreement has been applied in practice. As shown by the experience of Thailand, Brazil, and the Philippines, in order to deal effectively with international pressures for an excessive application of the TRIPS Agreement, some sort of conversion experience appears to be required, which then leads to a switch from a private enterprise, supply-driven approach to a public health vision that insists on universal and affordable access. But moral conviction is not sufficient. In order to muster and sustain the political will to face down international forces, civil society and government offices must be able and ready to show the costs and other adverse consequences of the TRIPS-based model for medicines. This calculation needs to reach beyond the health sector and calls for new alliances, nationally as well as internationally. © 2010 American Society of Law, Medicine & Ethics, Inc.
Takemine, S.; Rikimaru, A.; Takahashi, K.
The rice is one of the staple foods in the world High quality rice production requires periodically collecting rice growth data to control the growth of rice The height of plant the number of stem the color of leaf is well known parameters to indicate rice growth Rice growth diagnosis method based on these parameters is used operationally in Japan although collecting these parameters by field survey needs a lot of labor and time Recently a laborsaving method for rice growth diagnosis is proposed which is based on vegetation cover rate of rice Vegetation cover rate of rice is calculated based on discriminating rice plant areas in a digital camera image which is photographed in nadir direction Discrimination of rice plant areas in the image was done by the automatic binarization processing However in the case of vegetation cover rate calculation method depending on the automatic binarization process there is a possibility to decrease vegetation cover rate against growth of rice In this paper a calculation method of vegetation cover rate was proposed which based on the automatic binarization process and referred to the growth hysteresis information For several images obtained by field survey during rice growing season vegetation cover rate was calculated by the conventional automatic binarization processing and the proposed method respectively And vegetation cover rate of both methods was compared with reference value obtained by visual interpretation As a result of comparison the accuracy of discriminating rice plant areas was increased by the proposed
Implementation of Online Promethee Method for Poor Family Change Rate Calculation
Aji, Dhady Lukito; Suryono; Widodo, Catur Edi
2018-02-01
This research has been done online calculation of the rate of poor family change rate by using Preference Ranking Method of Organization Of Enrichment Evaluation (PROMETHEE) .This system is very useful to monitor poverty in a region as well as for administrative services related to poverty rate. The system consists of computer clients and servers connected via the internet network. Poor family residence data obtained from the government. In addition, survey data are inputted through the client computer in each administrative village and also 23 criteria of input in accordance with the established government. The PROMETHEE method is used to evaluate the value of poverty and its weight is used to determine poverty status. PROMETHEE output can also be used to rank the poverty of the registered population of the server based on the netflow value. The poverty rate is calculated based on the current poverty rate compared to the previous poverty rate. The rate results can be viewed online and real time on the server through numbers and graphs. From the test results can be seen that the system can classify poverty status, calculate the poverty rate change rate and can determine the value and poverty ranking of each population.
Implementation of Online Promethee Method for Poor Family Change Rate Calculation
Directory of Open Access Journals (Sweden)
Lukito Aji Dhady
2018-01-01
Full Text Available This research has been done online calculation of the rate of poor family change rate by using Preference Ranking Method of Organization Of Enrichment Evaluation (PROMETHEE .This system is very useful to monitor poverty in a region as well as for administrative services related to poverty rate. The system consists of computer clients and servers connected via the internet network. Poor family residence data obtained from the government. In addition, survey data are inputted through the client computer in each administrative village and also 23 criteria of input in accordance with the established government. The PROMETHEE method is used to evaluate the value of poverty and its weight is used to determine poverty status. PROMETHEE output can also be used to rank the poverty of the registered population of the server based on the netflow value. The poverty rate is calculated based on the current poverty rate compared to the previous poverty rate. The rate results can be viewed online and real time on the server through numbers and graphs. From the test results can be seen that the system can classify poverty status, calculate the poverty rate change rate and can determine the value and poverty ranking of each population.
A comparison of measured and calculated values of air kerma rates from 137Cs in soil
Directory of Open Access Journals (Sweden)
V. P. Ramzaev
2015-01-01
Full Text Available In 2010, a study was conducted to determine the air gamma dose rate from 137Cs deposited in soil. The gamma dose rate measurements and soil sampling were performed at 30 reference plots from the south-west districts of the Bryansk region (Russia that had been heavily contaminated as a result of the Chernobyl accident. The 137Cs inventory in the top 20 cm of soil ranged from 260 kBq m–2 to 2800 kBq m–2. Vertical distributions of 137Cs in soil cores (6 samples per a plot were determined after their sectioning into ten horizontal layers of 2 cm thickness. The vertical distributions of 137Cs in soil were employed to calculate air kerma rates, K, using two independent methods proposed by Saito and Jacob [Radiat. Prot. Dosimetry, 1995, Vol. 58, P. 29–45] and Golikov et al. [Contaminated Forests– Recent Developments in Risk Identification and Future Perspective. Kluwer Academic Publishers, 1999. – P. 333–341]. A very good coincidence between the methods was observed (Spearman’s rank coefficient of correlation = 0.952; P<0.01; on average, a difference between the kerma rates calculated with two methods did not exceed 3%. The calculated air kerma rates agreed with the measured dose rates in air very well (Spearman’s coefficient of correlation = 0.952; P<0.01. For large grassland plots (n=19, the measured dose rates were on average 6% less than the calculated kerma rates. The tested methods for calculating the air dose rate from 137Cs in soil can be recommended for practical studies in radiology and radioecology.
International Nuclear Information System (INIS)
Qin, H.L.; Xue, J.M.; Lai, J.N.; Wang, J.Y.; Zhang, W.M.; Miao, Q.; Yan, S.; Zhao, W.J.; He, F.; Gu, H.Y.; Wang, Y.G.
2006-01-01
In order to investigate the influence of ion energy on the germination and survival rates, water-imbibed Arabidopsis seeds were irradiated with protons in atmosphere. The ion fluence used in this experiment was in the range of 4 x 10 9 -1 x 10 14 ions/cm 2 . The ion energy is from 1.1 MeV to 6.5 MeV. According to the structure of the seed and TRIM simulation, the ions with the energy of 6.5 MeV can irradiate the shoot apical meristem directly whereas the ions with the energy of 1.1 MeV cannot. The results showed that both the germination and survival rates decrease while increasing the ion fluence, and the fluence-respond curve for each energy has different character. Besides the shoot apical meristem (SAM), which is generally considered as the main radiobiological target, the existence of a secondary target around SAM is proposed in this paper
International Nuclear Information System (INIS)
Xiao Yanni; Tang Sanyi
2008-01-01
Models of biological control have a long history of theoretical development that have focused on the interaction of a parasitoid and its host. The host-parasitoid systems have identified several important and general factors affecting the long-term dynamics of interacting populations. However, much less is known about how the initial densities of host-parasitoid populations affect the biological control as well as the stability of host-parasitoid systems. To do this, the classical Nicholson-Bailey model with host self-regulation and parasitoid intergenerational survival rate is used to uncover the effect of initial densities on the successful biological control. The results indicate that the simplest Nicholson-Bailey model has various coexistence with a wide range of parameters, including boundary attractors where the parasitoid population is absent and interior attractors where host-parasitoid coexists. The final stable states of host-parasitoid populations depend on their initial densities as well as their ratios, and those results are confirmed by basins of attraction of initial densities. The results also indicate that the parasitoid intergenerational survival rate increases the stability of the host-parasitoid systems. Therefore, the present research can help us to further understand the dynamical behavior of host-parasitoid interactions, to improve the classical biological control and to make management decisions
Modeling the effect of temperature on survival rate of Listeria monocytogenes in yogurt.
Szczawiński, J; Szczawińska, M E; Łobacz, A; Jackowska-Tracz, A
2016-01-01
The aim of the study was to (i) evaluate the behavior of Listeria monocytogenes in a commercially produced yogurt, (ii) determine the survival/inactivation rates of L. monocytogenes during cold storage of yogurt and (iii) to generate primary and secondary mathematical models to predict the behavior of these bacteria during storage at different temperatures. The samples of yogurt were inoculated with the mixture of three L. monocytogenes strains and stored at 3, 6, 9, 12 and 15°C for 16 days. The number of listeriae was determined after 0, 1, 2, 3, 5, 7, 9, 12, 14 and 16 days of storage. From each sample a series of decimal dilutions were prepared and plated onto ALOA agar (agar for Listeria according to Ottaviani and Agosti). It was found that applied temperature and storage time significantly influenced the survival rate of listeriae (pbacteria was found in the samples stored at 6°C (D-10 value = 243.9 h), whereas the highest reduction in the number of the bacteria was observed in the samples stored at 15°C (D-10 value = 87.0 h). The number of L. monocytogenes was correlated with the pH value of the samples (pyogurt stored under temperature range from 3 to 15°C, however, the polynomial model gave a better fit to the experimental data.
Energy Technology Data Exchange (ETDEWEB)
Qin, H.L. [Key Laboratory of Heavy Ion Physics, MOE, Peking University, Beijing 100871 (China); Xue, J.M. [Key Laboratory of Heavy Ion Physics, MOE, Peking University, Beijing 100871 (China); Lai, J.N. [Key Laboratory of Heavy Ion Physics, MOE, Peking University, Beijing 100871 (China); Wang, J.Y. [Key Laboratory of Heavy Ion Physics, MOE, Peking University, Beijing 100871 (China); Zhang, W.M. [Key Laboratory of Heavy Ion Physics, MOE, Peking University, Beijing 100871 (China); Miao, Q. [Key Laboratory of Heavy Ion Physics, MOE, Peking University, Beijing 100871 (China); Yan, S. [Key Laboratory of Heavy Ion Physics, MOE, Peking University, Beijing 100871 (China); Zhao, W.J. [Key Laboratory of Heavy Ion Physics, MOE, Peking University, Beijing 100871 (China); He, F. [School of Life Science, Peking University, Beijing 100871 (China); Gu, H.Y. [School of Life Science, Peking University, Beijing 100871 (China); Wang, Y.G. [Key Laboratory of Heavy Ion Physics, MOE, Peking University, Beijing 100871 (China)]. E-mail: ygwang@pku.edu.cn
2006-04-15
In order to investigate the influence of ion energy on the germination and survival rates, water-imbibed Arabidopsis seeds were irradiated with protons in atmosphere. The ion fluence used in this experiment was in the range of 4 x 10{sup 9}-1 x 10{sup 14} ions/cm{sup 2}. The ion energy is from 1.1 MeV to 6.5 MeV. According to the structure of the seed and TRIM simulation, the ions with the energy of 6.5 MeV can irradiate the shoot apical meristem directly whereas the ions with the energy of 1.1 MeV cannot. The results showed that both the germination and survival rates decrease while increasing the ion fluence, and the fluence-respond curve for each energy has different character. Besides the shoot apical meristem (SAM), which is generally considered as the main radiobiological target, the existence of a secondary target around SAM is proposed in this paper.
International Nuclear Information System (INIS)
Lee, Ching-Chih; Hung, Shih-Kai; Huang, Tze-Ta; Lee, Moon-Sing; Su, Yu-Chieh; Chou, Pesus; Hsiao, Shih-Hsuan; Chiou, Wen-Yen; Lin, Hon-Yi; Chien, Sou-Hsin
2011-01-01
Positive correlation between caseload and outcome has previously been validated for several procedures and cancer treatments. However, there is no information linking caseload and outcome of nasopharyngeal carcinoma (NPC) treatment. We used nationwide population-based data to examine the association between physician case volume and survival rates of patients with NPC. Between 1998 and 2000, a total of 1225 patients were identified from the Taiwan National Health Insurance Research Database. Survival analysis, the Cox proportional hazards model, and propensity score were used to assess the relationship between 10-year survival rates and physician caseloads. As the caseload of individual physicians increased, unadjusted 10-year survival rates increased (p < 0.001). Using a Cox proportional hazard model, patients with NPC treated by high-volume physicians (caseload ≥ 35) had better survival rates (p = 0.001) after adjusting for comorbidities, hospital, and treatment modality. When analyzed by propensity score, the adjusted 10-year survival rate differed significantly between patients treated by high-volume physicians and patients treated by low/medium-volume physicians (75% vs. 61%; p < 0.001). Our data confirm a positive volume-outcome relationship for NPC. After adjusting for differences in the case mix, our analysis found treatment of NPC by high-volume physicians improved 10-year survival rate
International Nuclear Information System (INIS)
Ran Xinze; Yan Yongtang; Cheng Tianmin; Li Yuan; Wei Shuqing
1996-01-01
The effects of combined radiation-burn injury on survival rate of allogeneic skin grafts and immune reaction were studied in rats with combined injury of 3-8 Gy 60 Co γ-ray irradiation plus 15% total body surface area full thickness burn induced by exposure to a 5 kw bromotungsten lamp. The allogeneic skin was transplanted 24 hours after injury. It was found that all the skin grafts failed to survive in 10 days and the immune reaction significantly increased in the early stage of burn injury. But the immune reaction was obviously suppressed by the combined radiation-burn injury. The survival rates of skin grafts were 20% and 30% in the combined injury of burn plus 3 and 4 Gy irradiation respectively. When the radiation doses increased to 5,6 and 8 Gy, the survival rates elevated to 69%, 88% and 100% respectively (in the group of 8 Gy, bone marrow transplantation was conducted before receiving skin graft). At day 30 post-transplantation the survival rates were still 36%, 42% and 100% respectively. Compared with burn group, there was a significant difference in survival rate when the radiation doses were higher than 5 Gy. These results indicate that the survival rate of the allogeneic skin graft increases concurrently with the increase in radiation dose and decreases with the elapse of the post-transplantation time
Survival, fidelity, and recovery rates of white-winged doves in Texas
Collier, Bret A.
2012-03-12
Management of migratory birds at the national level has historically relied on regulatory boundaries for definition of harvest restrictions and estimation of demographic parameters. Most species of migratory game birds are not expanding their ranges, so migratory corridors are approximately fixed. White-winged doves (Zenaida asiatica), however, have undergone significant variation in population structure with marked range expansion occurring in Texas, and range contraction in Arizona, during the last 30 years. Because >85% of white-winged dove harvest in the United States (approx. 1.3 million annually) now occurs in Texas, information on vital rates of expanding white-winged dove populations is necessary for informed management. We used band recovery and mark-recapture data to investigate variation in survival and harvest across 3 geographic strata for white-winged doves banded in the pre-hunting season in Texas during 2007-2010. We banded 60,742 white-winged doves, recovered 2,458 bands via harvest reporting, and recaptured 455 known-age birds between 2007 and 2010. The best supporting model found some evidence for geographic differences in survival rates among strata (A-C) in both hatch-year (juvenile; A = 0.205 [SE = 0.0476], B = 0.213 [SE = 0.0278], C = 0.364 [SE = 0.0254]) and after-hatch year (adult; A = 0.483 [SE = 0.0775], B = 0.465 [SE = 0.0366], C = 0.538 [SE = 0.251]) birds. White-winged doves had a low probability of moving among strata (0.009) or being recaptured (0.002) across all strata. Harvest recovery rates were concordant with estimates for other dove species, but were variable across geographic strata. Based on our results, harvest management strategies for white-winged doves in Texas and elsewhere should consider differences in population vital rates among geographic strata. © 2012 The Wildlife Society.
Apostolopoulos, Peter; Darby, Ivan
2017-04-01
Ridge preservation is any procedure that takes place at the time of, or shortly after an extraction, to minimise resorption of the ridge and maximise bone formation within the socket. The aim of this project is to investigate the outcome of implant treatment following ridge preservation and compare it to an ungrafted implant control group. Following ethics approval, an electronic and manual search of patient records was conducted, and appropriate cases of implant placement following a ridge preservation procedure were identified. Forty-two patients with 51 implants at ridge-preserved sites were examined by one author (PA) with the following parameters assessed at each implant: pocket probing depth, bleeding on probing, presence/absence of plaque and radiographic bone loss. Clinical and radiographic findings were compared to an ungrafted implant control group and analysed by years in function. There was a 100% survival rate of implants in ridge-preserved sites. In the majority of cases, ridge preservation was performed in the anterior maxilla with a flap raised and the use of deproteinised bovine bone mineral and collagen membrane materials. The mean time in function was 31 (±24) months with a range of 2-102 months. Differences in the mean PPD, BOP, plaque index and radiographic bone loss were not statistically significant between implants at ridge-preserved or ungrafted sites. The overall success rate was around 58% for ungrafted implants and around 51% for implants in ridge-preserved sites. However, this difference was not statistically significant. In this retrospective study, implant placement at ridge-preserved sites was a predictable procedure that led to very high survival rates and similar success rates to implant placement at ungrafted sites. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Directory of Open Access Journals (Sweden)
Zahra Rampisheh
2015-09-01
Full Text Available Background: Breast cancer is the most common female cancer worldwide. Survival rate of breast cancer, especially as an indicator of the successful implementation of screening, diagnosis and treatment programs, has been at the center of attention of public health experts Material and Methods: In a survival study, the records of breast cancer cases in cancer registry system of Bushehr Province were extracted during 2001, March to 2013, September. These records were linked and matched with records of death registry system. After determining patients, status regarding being alive or dead, survival analysis was done. Life table, Kaplan-Mayer analysis, log rank and Breslow tests were used for computing and comparing survival rates. Results: In 300 recorded breast cancer cases, mean and standard deviation of age was 51.26±13.87. Survival rates were 95, 88, 78, 73 and 68 percent since the first year through the fifth year, respectively. Mean survival was 87.20 months (95% CI= 81.28- 93.12. There was no significant difference in mean survival regarding age and different geographical areas. Conclusion: Although survival rates of registered breast cancer patients in Bushehr Province are similar to other provinces, they are far from those of developed countries. This situation demands more extensive efforts regarding public education and improving the process of diagnosis, treatment and care of patients especially during first two years after diagnosis.
Calculation of heat rating and burn-up for test fuel pins irradiated in DR 3
International Nuclear Information System (INIS)
Bagger, C.; Carlsen, H.; Hansen, K.
1980-01-01
A summary of the DR 3 reactor and HP1 rig design is given followed by a detailed description of the calculation procedure for obtaining linear heat rating and burn-up values of fuel pins irradiated in HP1 rigs. The calculations are carried out rather detailed, especially regarding features like end pellet contribution to power as a function of burn-up, gamma heat contributions, and evaluation of local values of heat rating and burn-up. Included in the report is also a description of the fast flux- and cladding temperature calculation techniques currently used. A good agreement between measured and calculated local burn-up values is found. This gives confidence to the detailed treatment of the data. (author)
International Nuclear Information System (INIS)
2002-01-01
Calculations with the quadratic lineal model for medium rate using the equation dose-effect. Several calculations for system of low dose rate brachytherapy plus teletherapy, calculations for brachytherapy with medium dose rate together with teletherapy, dose for fraction and the one numbers of fractions in medium rate
Large-scale calculations of the beta-decay rates and r-process nucleosynthesis
Energy Technology Data Exchange (ETDEWEB)
Borzov, I N; Goriely, S [Inst. d` Astronomie et d` Astrophysique, Univ. Libre de Bruxelles, Campus Plaine, Bruxelles (Belgium); Pearson, J M [Inst. d` Astronomie et d` Astrophysique, Univ. Libre de Bruxelles, Campus Plaine, Bruxelles (Belgium); [Lab. de Physique Nucleaire, Univ. de Montreal, Montreal (Canada)
1998-06-01
An approximation to a self-consistent model of the ground state and {beta}-decay properties of neutron-rich nuclei is outlined. The structure of the {beta}-strength functions in stable and short-lived nuclei is discussed. The results of large-scale calculations of the {beta}-decay rates for spherical and slightly deformed nuclides of relevance to the r-process are analysed and compared with the results of existing global calculations and recent experimental data. (orig.)
Calculation of the ingestion critical dose rate for the Goiania radioactive waste repository
International Nuclear Information System (INIS)
Passos, E.M. dos; Martin Alves, A.S. De
1994-01-01
The calculation results of the critical distance for the ingestion dose rate due to a hypothetical Cs-137 release from the Abadia de Goias repository are shown. The work is based on the pathway repository-aquifer-well food chain. The calculations were based upon analytical models for the migration of radioisotopes through the aquifer and for its transfer from well water to food. (author)
International Nuclear Information System (INIS)
Hoefler, A.; Grebner, H.
1992-01-01
Calculations of leak opening and leak rate for through cracks in piping components have been performed. The analyses are pre- or mostly post-calculations to experiments performed at the HDR facility under PWR operating conditions. Piping components under consideration are small diameter straight pipes with circumferential cracks, pipe bends with longitudinal or circumferential cracks and pipe branches with weldment cracks. The component are loaded by internal pressure and opening as well as closing bending moment. The finite element method and two-phase flow leak rate programs are used for the calculations. Results of the analyses are presented as J-integral values, crack opening displacements and areas and leak rates as well as comparisons to the experimental results. 6 refs., 16 figs., 2 tabs
Comparison of leak opening and leak rate calculations to HDR experimental results
International Nuclear Information System (INIS)
Grebner, H.; Hoefler, A.; Hunger, H.
1993-01-01
During the last years a number of calculations of leak opening and leak rate for through cracks in piping components have been performed. Analyses are pre- or mostly post-calculations to experiments performed at the HDR facility under PWR operating conditions. Piping components under consideration were small diameter straight pipes with circumferential cracks, pipe bends with longitudinal or circumferential cracks and pipe branches with weldment cracks. The components were loaded by internal pressure and opening as well as closing bending moment. The finite element method and two-phase flow leak rate programs were used for the calculations. Results of the analyses are presented as J-integral values, crack opening displacements and areas and leak rates as well as comparisons to the experimental results
Calculation of the gamma-dose rate from a continuously emitted plume
International Nuclear Information System (INIS)
Huebschmann, W.; Papadopoulos, D.
1975-06-01
A computer model is presented which calculates the long term gamma dose rate caused by the radioactive off-gas continuously emitted from a stack. The statistical distribution of the wind direction and velocity and of the stability categories is taken into account. The emitted activity, distributed in the atmosphere according to this statistics, is assumed to be concentrated at the mesh points of a three-dimensional grid. The grid spacing and the integration limits determine the accuracy as well as the computer time needed. When calculating the dose rate in a given wind direction, the contribution of the activity emitted into the neighbouring sectors is evaluated. This influence is demonstrated in the results, which are calculated with a error below 3% and compared to the dose rate distribution curves of the submersion model and the model developed by K.J. Vogt. (orig.) [de
Relativistic QRPA Calculation of β-Decay Rates of r-process Nuclei
International Nuclear Information System (INIS)
Marketin, T.; Paar, N.; Niksic, T.; Vretenar, D.; Ring, P.
2009-01-01
A systematic, fully self-consistent calculation of β-decay rates is presented, based on a microscopic theoretical framework. Analysis is performed on a large number of nuclei from the valley of β stability towards the neutron drip-line. Nuclear ground state is determined using the Relativistic Hartree-Bogoliubov (RHB) model with density-dependent meson-nucleon coupling constants. Transition rates are calculated within the proton-neutron relativistic quasiparticle RPA (pn-RQRPA) using the same interaction that was used in the RHB equations.
American Society for Testing and Materials. Philadelphia
1989-01-01
1.1 This practice covers the providing of guidance in converting the results of electrochemical measurements to rates of uniform corrosion. Calculation methods for converting corrosion current density values to either mass loss rates or average penetration rates are given for most engineering alloys. In addition, some guidelines for converting polarization resistance values to corrosion rates are provided. 1.2 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard.
Calculation of dose-rate conversion factors for external exposure to photons and electrons
International Nuclear Information System (INIS)
Kocher, D.C.
1978-01-01
Methods are presented for the calculation of dose-rate conversion factors for external exposure to photon and electron radiation from radioactive decay. A dose-rate conversion factor is defined as the dose-equivalent rate per unit radionuclide concentration. Exposure modes considered are immersion in contaminated air, immersion in contaminated water, and irradiation from a contaminated ground surface. For each radiation type and exposure mode, dose-rate conversion factors are derived for tissue-equivalent material at the body surface of an exposed individual. In addition, photon dose-rate conversion factors are estimated for 22 body organs. The calculations are based on the assumption that the exposure medium is infinite in extent and that the radionuclide concentration is uniform. The dose-rate conversion factors for immersion in contaminated air and water then follow from the requirement that all of the energy emitted in the radioactive decay is absorbed in the infinite medium. Dose-rate conversion factors for ground-surface exposure are calculated at a reference location above a smooth, infinite plane using the point-kernel integration method and known specific absorbed fractions for photons and electrons in air
International Nuclear Information System (INIS)
Cowley, S.C.; Kulsrud, R.M.
1989-11-01
We calculate the fusion reaction rates in molecules of hydrogen isotopes. The rates are calculated analytically (for the first time) as an asymptotic expansion in the ratio of the electron mass to the reduced mass of the nucleii. The fusion rates of the P-D, D-D, and D-T reactions are given for a variable electron mass by a simple analytic formula. However, we do not know any mechanism by which a sufficiently localized electron in solid can have an 'effective mass' large enough to explain the result of Fleischman and Pons (FP). This calculation indicates that P-D rates should exceed D-D rates for D-D fusion rates less than approximately 10 -23 per molecule per second. The D-D fusion rate is enhanced by a factor of 10 5 at 10,000 degree K if the excited vibrational states are populated with a Boltzmann distribution and the rotational excitations suppressed. The suggestion that experimental results could be explained by bombardment of cold deuterons by kilovolt deuterons is shown to be an unlikely from an energetic point of view. 12 refs., 3 figs., 1 tab
National Oceanic and Atmospheric Administration, Department of Commerce — The projectâs objective is to document movement patterns and survival rates of Chinook salmon, steelhead, green sturgeon, and other fish from several sources in...
Yamazaki, Seiya; Arakawa, Hikaru; Maekawa, Kenji; Hara, Emilio Satoshi; Noda, Kinji; Minakuchi, Hajime; Sonoyama, Wataru; Matsuka, Yoshizo; Kuboki, Takuo
2013-07-01
This study aimed to compare the survival rates of remaining teeth between implant-supported fixed dentures (IFDs) and removable partial dentures (RPDs) in patients with large edentulous cases. The second goal was to assess the risk factors for remaining tooth loss. The study subjects were selected among those who received prosthodontic treatment at Okayama University Dental Hospital for their edentulous space exceeding at least four continuous missing teeth. Twenty-one patients were included in the IFD group and 82 patients were included in the RPD group. Survival rates of remaining teeth were calculated in three subcategories: (1) whole remaining teeth, (2) adjacent teeth to intended edentulous space, and (3) opposing teeth to intended edentulous space. The ten-year cumulative survival rate of the whole remaining teeth was significantly higher in the IFD group (40.0%) than in the RPD group (24.4%). On the other hand, there was no significant difference between two groups in the survival rate of teeth adjacent or opposing to intended edentulous space. A Cox proportional hazard analysis revealed that RPD restoration and gender (male) were the significant risk factors for remaining tooth loss (whole remaining teeth). These results suggest that IFD treatment can reduce the incidence of remaining tooth loss in large edentulous cases. Copyright © 2013 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.
International Nuclear Information System (INIS)
Horas, Jorge A; Olguin, Osvaldo R; Rizzotto, Marcos G
2005-01-01
We model the heterogeneous response to radiation of multicellular tumour spheroids assuming position- and volume-dependent radiosensitivity. We propose a method to calculate the overall radiosensitivity parameters to obtain the surviving fraction of tumours. A mathematical model of a spherical tumour with a hypoxic core and a viable rim which is a caricature of a real tumour is constructed. The model is embedded in a two-compartment linear-quadratic (LQ) model, assuming a mixed bivariated Gaussian distribution to attain the radiosensitivity parameters. Ergodicity, i.e., the equivalence between ensemble and volumetric averages is used to obtain the overall radiosensitivities for the two compartments. We obtain expressions for the overall radiosensitivity parameters resulting from the use of both a linear and a nonlinear dependence of the local radiosensitivity with position. The model's results are compared with experimental data of surviving fraction (SF) for multicellular spheroids of different sizes. We make one fit using only the smallest spheroid data and we are able to predict the SF for the larger spheroids. These predictions are acceptable particularly using bounded sensitivities. We conclude with the importance of taking into account the contribution of clonogenic hypoxic cells to radiosensitivity and with the convenience of using bounded local sensitivities to predict overall radiosensitivity parameters
International Nuclear Information System (INIS)
Klasen, M.; Kramer, G.
2009-08-01
We perform next-to-leading order calculations of the single-diffractive and non-diffractive cross sections for dijet production in proton-antiproton collisions at the Tevatron. By comparing their ratio to the data published by the CDF collaboration for two different center-of-mass energies, we deduce the rapidity-gap survival probability as a function of the momentum fraction of the parton in the antiproton. Assuming Regge factorization, this probability can be interpreted as a suppression factor for the diffractive structure function measured in deep-inelastic scattering at HERA. In contrast to the observations for photoproduction, the suppression factor in protonantiproton collisions depends on the momentum fraction of the parton in the Pomeron even at next-to-leading order. (orig.)
DEFF Research Database (Denmark)
Simone, Angela; Kolarik, Jakub; Iwamatsu, Toshiya
2011-01-01
occupants, it is reasonable to consider both the exergy flows in building and those within the human body. Until now, no data have been available on the relation between human-body exergy consumption rates and subjectively assessed thermal sensation. The objective of the present work was to relate thermal...... sensation data, from earlier thermal comfort studies, to calculated human-body exergy consumption rates. The results show that the minimum human body exergy consumption rate is associated with thermal sensation votes close to thermal neutrality, tending to the slightly cool side of thermal sensation....... Generally, the relationship between air temperature and the exergy consumption rate, as a first approximation, shows an increasing trend. Taking account of both convective and radiative heat exchange between the human body and the surrounding environment by using the calculated operative temperature, exergy...
Directory of Open Access Journals (Sweden)
Zhihong Feng
2017-01-01
Full Text Available We aimed to investigate the efficacy of four severity-of-disease scoring systems in predicting the 28-day survival rate among patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD requiring emergency care. Clinical data of patients with AECOPD who required emergency care were recorded over 2 years. APACHE II, SAPS II, SOFA, and MEDS scores were calculated from severity-of-disease indicators recorded at admission and compared between patients who died within 28 days of admission (death group; 46 patients and those who did not (survival group; 336 patients. Compared to the survival group, the death group had a significantly higher GCS score, frequency of comorbidities including hypertension and heart failure, and age (P<0.05 for all. With all four systems, scores of age, gender, renal inadequacy, hypertension, coronary heart disease, heart failure, arrhythmia, anemia, fracture leading to bedridden status, tumor, and the GCS were significantly higher in the death group than the survival group. The prediction efficacy of the APACHE II and SAPS II scores was 88.4%. The survival rates did not differ significantly between APACHE II and SAPS II (P=1.519. Our results may guide triage for early identification of critically ill patients with AECOPD in the emergency department.
Survival Rate and Growth of Fighting Fish Larvae (Betta splendens Regan Fed on Various Live Foods
Directory of Open Access Journals (Sweden)
T. Budiardi
2007-01-01
Full Text Available Larval of fighting fish (Betta splendens Regan requires precise live foods for its growth and survival. In this experiment, fish larvae were fed on either Paramecium + Artemia, Paramecium + Artemia + Tubifex, Paramecium + Moina, or Paramecium + Moina + Tubifex. The fish were fed Paramecium from day-2 till day-7 after hatching. There after, the live food was changed according to the treatments till day-28. Results showed that fish fed on Paramecium + Artemia significantly had the highest total length (12.63 mm than other treatments (11.86 mm. On the other hand, survival rate of fish had no significant affected by the treatments. Keywords: fighting fish, Betta splendens, Paramecium, Moina, Artemia, Tubifex, larvae ABSTRAK Larva ikan betta (Betta splendens Regan membutuhkan jenis pakan alami yang tepat bagi kelangsungan hidup dan pertumbuhannya. Pada penelitian ini, larva ikan diberi pakan berupa Paramecium + Artemia, Paramecium + Artemia + Tubifex, Paramecium + Moina, atau Paramecium + Moina + Tubifex. Ikan diberi pakan pakan berupa Paramecium dari hari ke-2 hingga hari ke-7. Setelah itu, pemberian pakan alami diubah berdasarkan masing-masing perlakuan hingga hari ke-28. Hasil penelitian menunjukkan bahwa ikan yang diberi pakan Paramecium + Artemia memiliki tubuh secara signifikan lebih panjang (12,63 mm dibandingkan perlakuan lainnya (11,86 mm. Sementara itu, kelangsungan hidup tidak dipengatuhi oleh perlakuan. Kata kunci: ikan betta, Betta splendens, Paramecium, Moina, Artemia, Tubifex, larva
Outpatient-shopping behavior and survival rates in newly diagnosed cancer patients.
Chiou, Shang-Jyh; Wang, Shiow-Ing; Liu, Chien-Hsiang; Yaung, Chih-Liang
2012-09-01
To evaluate the appropriateness of the definition of outpatient-shopping behavior in Taiwanese patients. Linked study of 3 databases (Taiwan Cancer Registry, National Health Insurance [NHI] claim database, and death registry database). Outpatient shopping behavior was defined as making at least 4 or 5 physician visits to confirm a cancer diagnosis. We analyzed patient-related factors and the 5-year overall survival rate of the outpatient-shopping group compared with a nonshopping group. Using the household registration database and NHI database, we determined the proportion of outpatient shopping, characteristics of patients who did and did not shop for outpatient therapy, time between diagnosis and start of regular treatment, and medical service utilization in the shopping versus the nonshopping group. Patients with higher incomes were significantly more likely to shop for outpatient care. Patients with higher comorbidity scores were 1.4 times more likely to shop for outpatient care than patients with lower scores. Patients diagnosed with more advanced cancer were more likely to shop than those who were not. Patients might be more trusting of cancer diagnoses given at higher-level hospitals. The nonshopping groups had a longer duration of survival over 5 years. Health authorities should consider charging additional fees after a specific outpatient- shopping threshold is reached to reduce this behavior. The government may need to reassess the function of the medical sources network by shrinking it from the original 4 levels to 2 levels, or by enhancing the referral function among different hospital levels.
Axelrod, David
2017-01-01
This paper describes how the discount rate used in present value calculations expresses the preference for sustainability in decision making, and its implication for sustainable economic growth. In essence, the lower the discount rate, the greater the regard for the future, and the more likely we choose behaviors that lead to long-term sustainability. The theoretical framework combines behavioral economics and holonomics, which involve limitations of regard for the future due to constraints o...
Panthere V2: Multipurpose Simulation Software for 3D Dose Rate Calculations
Penessot, Gaël; Bavoil, Éléonore; Wertz, Laurent; Malouch, Fadhel; Visonneau, Thierry; Dubost, Julien
2017-09-01
PANTHERE is a multipurpose radiation protection software developed by EDF to calculate gamma dose rates in complex 3D environments. PANTHERE takes a key role in the EDF ALARA process, enabling to predict dose rates and to organize and optimize operations in high radiation environments. PANTHERE is also used for nuclear waste characterization, transport of nuclear materials, etc. It is used in most of the EDF engineering units and their design service providers and industrial partners.
Yang, Huan; Goudeli, Eirini; Hogan, Christopher J.
2018-04-01
In gas phase synthesis systems, clusters form and grow via condensation, in which a monomer binds to an existing cluster. While a hard-sphere equation is frequently used to predict the condensation rate coefficient, this equation neglects the influences of potential interactions and cluster internal energy on the condensation process. Here, we present a collision rate theory-molecular dynamics simulation approach to calculate condensation probabilities and condensation rate coefficients. We use this approach to examine atomic condensation onto 6-56-atom Au and Mg clusters. The probability of condensation depends upon the initial relative velocity (v) between atom and cluster and the initial impact parameter (b). In all cases, there is a well-defined region of b-v space where condensation is highly probable, and outside of which the condensation probability drops to zero. For Au clusters with more than 10 atoms, we find that at gas temperatures in the 300-1200 K range, the condensation rate coefficient exceeds the hard-sphere rate coefficient by a factor of 1.5-2.0. Conversely, for Au clusters with 10 or fewer atoms and for 14- and 28-atom Mg clusters, as cluster equilibration temperature increases, the condensation rate coefficient drops to values below the hard-sphere rate coefficient. Calculations also yield the self-dissociation rate coefficient, which is found to vary considerably with gas temperature. Finally, calculations results reveal that grazing (high b) atom-cluster collisions at elevated velocity (>1000 m s-1) can result in the colliding atom rebounding (bounce) from the cluster surface or binding while another atom dissociates (replacement). The presented method can be applied in developing rate equations to predict material formation and growth rates in vapor phase systems.
Calculation of radiation dose rates from a spent nuclear fuel shipping cask
International Nuclear Information System (INIS)
Chen, S.Y.; Yuan, Y.C.
1988-01-01
Radiation doses from a spent nuclear fuel cask are usually from various phases of operations during handling, shipping, and storage of the casks. Assessment of such doses requires knowledge of external radiation dose rates at various locations surrounding a cask. Under current practices, dose rates from gamma photons are usually estimated by means of point- or line-source approaches incorporating the conventional buildup factors. Although such simplified approaches may at times be easy to use, their accuracy has not been verified. For example, those simplified methods have not taken into account influencing factors such as the geometry of the cask and the presence of the ground surface, and the effects of these factors on the calculated dose rates are largely unknown. Moreover, similar empirical equations for buildup factors currently do not exist for neutrons. The objective of this study is to use a more accurate approach in calculating radiation dose rates for both neutrons and gamma photons from a spent fuel cask. The calculation utilizes the more sophisticated transport method and takes into account the geometry of the cask and the presence of the ground surface. The results of a detailed study of dose rates in the near field (within 20 meters) are presented and, for easy application, the cask centerline dose rates are fitted into empirical equations at cask centerline distances up to 2000 meters from the surface of the cask
International Nuclear Information System (INIS)
Nishimura, Yasumasa; Hosotani, Ryo; Shibamoto, Yuta; Kokubo, Masaki; Kanamori, Shuichi; Sasai, Keisuke; Hiraoka, Masahiro; Ohshio, Gakuji; Imamura, Masayuki; Takahashi, Masaji; Abe, Mitsuyuki
1997-01-01
Purpose: Clinical results of intraoperative radiotherapy (IORT) and/or external beam radiotherapy (EBRT) for both resectable and unresectable pancreatic cancer were analyzed. Methods and Materials: Between 1980 and 1995, 332 patients with pancreatic cancer were treated with surgery and/or radiation therapy (RT). Of the 332 patients, 157 patients were treated with surgical resection of pancreatic tumor, and the remaining 175 patients had unresectable pancreatic tumors. Among the 157 patients with resected pancreatic cancer, 62 patients were not treated with RT, while 40 patients were treated with EBRT alone (mean RT dose; 46.3 Gy) and 55 patients with IORT (25.2 Gy) ± EBRT (44.0 Gy). On the other hand, among the 175 patients with unresectable pancreatic cancer, 58 patients were not treated with RT, 46 patients were treated with EBRT alone (39.2 Gy), and the remaining 71 patients with IORT (29.3 Gy) ± EBRT (41.2 Gy). Results: For 87 patients with curative resection, the median survival times (MSTs) of the no-RT, the EBRT, and the IORT ± EBRT groups were 10.4, 13.0, and 15.5 months, respectively, without significant difference. For 70 patients with non curative resection, the MSTs of the no-RT, the EBRT, and the IORT ± EBRT groups were 5.3, 8.7, and 6.5 months, respectively. When the EBRT and the IORT ± EBRT groups were combined, the survival rate was significantly higher than that of the no RT group for non curatively resected pancreatic cancers (log rank test; p = 0.028). The 2-year survival probability of the IORT ± EBRT group (16%) was higher than that of the EBRT group (0%). For unresectable pancreatic cancer, the MSTs of 52 patients without distant metastases were 6.7 months for palliative surgery alone, 7.6 months for EBRT alone, and 8.2 months for IORT ± EBRT. The survival curve of the IORT ± EBRT group was significantly better than that of the no-RT group (p 2 years) were obtained by IORT ± EBRT for non curatively resected and unresectable pancreatic
Pruksakorn, Dumnoensun; Phanphaisarn, Areerak; Arpornchayanon, Olarn; Uttamo, Nantawat; Leerapun, Taninnit; Settakorn, Jongkolnee
2015-12-01
Osteosarcoma is a common and aggressive primary malignant bone tumor occurring in children and adolescents. It is one of the most aggressive human cancers and the most common cause of cancer-associated limb loss. As treatment in Thailand has produced a lower survival rate than in developed countries; therefore, this study identified survival rate and the poor prognostic factors of osteosarcoma in Northern Thailand. The retrospective cases of osteosarcoma, diagnosis between 1 January 1996 and 31 December 2013, were evaluated. Five and ten year overall survival rates were analyzed using time-to-event analysis. Potential prognostic factors were identified by multivariate regression analysis. There were 208 newly diagnosed osteosarcomas during that period, and 144 cases met the criteria for analysis. The majority of the osteosarcoma cases (78.5%) were aged 0-24 years. The overall 5- and 10-year survival rates were 37.9% and 33.6%, respectively. Presence of metastasis at initial examination, delayed and against treatment co-operation, and axial skeletal location were identified as independent prognostic factors for survival, with hazard ratios of 4.3, 2.5 and 3.8, and 3.1, respectively. This osteosarcoma cohort had a relatively poor overall survival rate. The prognostic factors identified would play a critical role in modifying survival rates of osteosarcoma patients; as rapid disease recognition, a better treatment counselling, as well as improving of chemotherapeutic regimens were found to be important in improving the overall survival rate in Thailand. Copyright © 2015 Elsevier Ltd. All rights reserved.
International Nuclear Information System (INIS)
Ni Zhipeng; Wang Liangbin; Li Jiangang; Chen Zhiyou; Zhang Yong; Wang Futang
2008-01-01
An electromagnetic calculation and the parameters of the magnet system of the magnetically confined plasma rocket were established. By using ANSYS code, it was found that the leakage rate depends on the current intensity of the magnet and the change of the magnet position.
Zinth, Jennifer
2018-01-01
Federal requirements stipulate that states and local education agencies annually calculate and report an Adjusted Cohort Graduation Rate, disaggregated by student group. The ACGR includes all students who graduate from high school in four years with a regular high school diploma, plus all students with the most significant cognitive disabilities…
39 CFR 3010.23 - Calculation of percentage change in rates.
2010-07-01
... DOMINANT PRODUCTS Rules for Applying the Price Cap § 3010.23 Calculation of percentage change in rates. (a... Postal Service billing determinants. The Postal Service shall make reasonable adjustments to the billing determinants to account for the effects of classification changes such as the introduction, deletion, or...
20 CFR 10.216 - How is the pay rate for COP calculated?
2010-04-01
... for COP purposes is equal to the employee's regular “weekly” pay (the average of the weekly pay over... occurred during the 45-day period are to be reflected in the weekly pay determination. (b) The weekly pay... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false How is the pay rate for COP calculated? 10...
Results of Propellant Mixing Variable Study Using Precise Pressure-Based Burn Rate Calculations
Stefanski, Philip L.
2014-01-01
A designed experiment was conducted in which three mix processing variables (pre-curative addition mix temperature, pre-curative addition mixing time, and mixer speed) were varied to estimate their effects on within-mix propellant burn rate variability. The chosen discriminator for the experiment was the 2-inch diameter by 4-inch long (2x4) Center-Perforated (CP) ballistic evaluation motor. Motor nozzle throat diameters were sized to produce a common targeted chamber pressure. Initial data analysis did not show a statistically significant effect. Because propellant burn rate must be directly related to chamber pressure, a method was developed that showed statistically significant effects on chamber pressure (either maximum or average) by adjustments to the process settings. Burn rates were calculated from chamber pressures and these were then normalized to a common pressure for comparative purposes. The pressure-based method of burn rate determination showed significant reduction in error when compared to results obtained from the Brooks' modification of the propellant web-bisector burn rate determination method. Analysis of effects using burn rates calculated by the pressure-based method showed a significant correlation of within-mix burn rate dispersion to mixing duration and the quadratic of mixing duration. The findings were confirmed in a series of mixes that examined the effects of mixing time on burn rate variation, which yielded the same results.
P-cadherin expression and survival rate in oral squamous cell carcinoma:an immunohistochemical study
Directory of Open Access Journals (Sweden)
Laino Gregorio
2005-06-01
Full Text Available Abstract Background P-cadherin (P-cad is a transmembrane molecule involved in the cell-cell adhesion and similar to E-cadherin (E-cad, but less investigated in oncology, especially in in vivo studies. Aims of the present study were to assess the prevalence of P-cad expression in oral squamous cell carcinoma (OSCC and to verify whether P-cad can be considered a marker of prognosis in patients with OSCC. Methods In a retrospective study, a cohort of 67 OSCC patients was investigated for P-cad expression and its cellular localization by immunohistochemistry; some respective healthy margins of resection were similarly investigated as standard controls. After grouping for P-cad expression, OSCCs were statistically analyzed for the variables age, gender, histological grading (G, TNM, Staging, and overall survival rate. Univariate and multivariate analyses were performed. Results 37 cases (55.2% of OSCC showed membranous/cytoplasmic positivity for P-cad, whereas 30 (44.8 % were negative. Although with some differences in membranous vs cytoplasmic localization of P-cad in OSCC with different G, no statistical association was found between P-cad expression and any variables considered at baseline. In terms of prognostic significance, P-cad non expression was found to have an independent association with poorer overall survival rate than P-cad expressing group (P = 0.056; moreover, among P-cad +ve patients the best prognosis was for those OSCC with membranous (P Conclusion On the basis of these results, it is possible to suggest P-cad as an early marker of poor prognosis. The abnormal or lack of P-cad expression could constitute an hallmark of aggressive biological behavior in OSCC
Relativistic QRPA calculation of β-decay rates of r-process nuclei
International Nuclear Information System (INIS)
Marketin, T.; Paar, N.; Niksic, T.
2009-01-01
The rapid neutron-capture process (r-process) is responsible for the creation of many nuclei heavier than iron. To describe the r-process, precise data is needed on a large number of neutron-rich nuclei, most of which are not experimentally reachable. One crucial parameter in modeling the nucleosynthesis are the half-lives of the nuclei through which the r-process runs. Therefore, it is of great importance to develop a reliable predictive model which can be applied to the decay of exotic nuclei. A fully self-consistent calculation of β-decay rates is presented, based on a microscopic theoretical framework. Nuclear ground state is determined using the Relativistic Hartree-Bogoliubov (RHB) model with density-dependent meson-nucleon coupling constants. Momentum dependent terms are also included to improve the density of single-particle states around the Fermi level via an increase of the effective nucleon mass [1]. Transition rates are calculated within the proton-neutron relativistic quasiparticle RPA using the same interaction that was used in the RHB equations. In this way no additional parameters are introduced in the RPA calculation. Weak interaction rates are calculated using the current-current formalism previously employed in the study of other astrophysically significant weak processes [2,3], which systematically includes the contributions of forbidden transitions. This theoretical framework will be utilized to study the contributions of forbidden transitions to the total decay rate in several mass regions. We will compare the calculated half-lives for several isotopic chains with previous calculations and experimental data and discuss possible improvements to the model.(author)
Chloroquine Improves Survival and Hematopoietic Recovery After Lethal Low-Dose-Rate Radiation
International Nuclear Information System (INIS)
Lim Yiting; Hedayati, Mohammad; Merchant, Akil A.; Zhang Yonggang; Yu, Hsiang-Hsuan M.; Kastan, Michael B.; Matsui, William; DeWeese, Theodore L.
2012-01-01
Purpose: We have previously shown that the antimalarial agent chloroquine can abrogate the lethal cellular effects of low-dose-rate (LDR) radiation in vitro, most likely by activating the ataxia-telangiectasia mutated (ATM) protein. Here, we demonstrate that chloroquine treatment also protects against lethal doses of LDR radiation in vivo. Methods and Materials: C57BL/6 mice were irradiated with a total of 12.8 Gy delivered at 9.4 cGy/hour. ATM null mice from the same background were used to determine the influence of ATM. Chloroquine was administered by two intraperitoneal injections of 59.4 μg per 17 g of body weight, 24 hours and 4 hours before irradiation. Bone marrow cells isolated from tibia, fibula, and vertebral bones were transplanted into lethally irradiated CD45 congenic recipient mice by retroorbital injection. Chimerism was assessed by flow cytometry. In vitro methylcellulose colony-forming assay of whole bone marrow cells and fluorescence activated cell sorting analysis of lineage depleted cells were used to assess the effect of chloroquine on progenitor cells. Results: Mice pretreated with chloroquine before radiation exhibited a significantly higher survival rate than did mice treated with radiation alone (80% vs. 31%, p = 0.0026). Chloroquine administration before radiation did not affect the survival of ATM null mice (p = 0.86). Chloroquine also had a significant effect on the early engraftment of bone marrow cells from the irradiated donor mice 6 weeks after transplantation (4.2% vs. 0.4%, p = 0.015). Conclusion: Chloroquine administration before radiation had a significant effect on the survival of normal but not ATM null mice, strongly suggesting that the in vivo effect, like the in vitro effect, is also ATM dependent. Chloroquine improved the early engraftment of bone marrow cells from LDR-irradiated mice, presumably by protecting the progenitor cells from radiation injury. Chloroquine thus could serve as a very useful drug for protection
Directory of Open Access Journals (Sweden)
Chou Pesus
2011-08-01
Full Text Available Abstract Background Positive correlation between caseload and outcome has previously been validated for several procedures and cancer treatments. However, there is no information linking caseload and outcome of nasopharyngeal carcinoma (NPC treatment. We used nationwide population-based data to examine the association between physician case volume and survival rates of patients with NPC. Methods Between 1998 and 2000, a total of 1225 patients were identified from the Taiwan National Health Insurance Research Database. Survival analysis, the Cox proportional hazards model, and propensity score were used to assess the relationship between 10-year survival rates and physician caseloads. Results As the caseload of individual physicians increased, unadjusted 10-year survival rates increased (p p = 0.001 after adjusting for comorbidities, hospital, and treatment modality. When analyzed by propensity score, the adjusted 10-year survival rate differed significantly between patients treated by high-volume physicians and patients treated by low/medium-volume physicians (75% vs. 61%; p Conclusions Our data confirm a positive volume-outcome relationship for NPC. After adjusting for differences in the case mix, our analysis found treatment of NPC by high-volume physicians improved 10-year survival rate.
Increased survival rate by local release of diclofenac in a murine model of recurrent oral carcinoma
Directory of Open Access Journals (Sweden)
Will OM
2016-10-01
Full Text Available Olga Maria Will,1,* Nicolai Purcz,2,* Athena Chalaris,3 Carola Heneweer,4,5 Susann Boretius,1 Larissa Purcz,2 Lila Nikkola,6 Nureddin Ashammakhi,6 Holger Kalthoff,7 Claus-Christian Glüer,1 Jörg Wiltfang,2 Yahya Açil,2 Sanjay Tiwari1 1Section Biomedical Imaging, Clinic for Radiology and Neuroradiology, MOIN CC, 2Department of Oral and Maxillofacial Surgery, University Hospital Schleswig-Holstein, 3Institute of Biochemistry, Christian-Albrechts-Universität zu Kiel, 4Clinic for Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel, 5Institute for Diagnostic and Interventional Radiology, University Hospital Cologne, Cologne, Germany; 6Department of Biomedical Engineering, Tampere University of Technology, Tampere, Finland; 7Institute for Experimental Cancer Research, University Hospital Schleswig-Holstein, Kiel, Germany *These authors contributed equally to this work Abstract: Despite aggressive treatment with radiation and combination chemotherapy following tumor resection, the 5-year survival rate for patients with head and neck cancer is at best only 50%. In this study, we examined the therapeutic potential of localized release of diclofenac from electrospun nanofibers generated from poly(d,l-lactide-co-glycolide polymer. Diclofenac was chosen since anti-inflammatory agents that inhibit cyclooxygenase have shown great potential in their ability to directly inhibit tumor growth as well as suppress inflammation-mediated tumor growth. A mouse resection model of oral carcinoma was developed by establishing tumor growth in the oral cavity by ultrasound-guided injection of 1 million SCC-9 cells in the floor of the mouth. Following resection, mice were allocated into four groups with the following treatment: 1 no treatment, 2 implanted scaffolds without diclofenac, 3 implanted scaffolds loaded with diclofenac, and 4 diclofenac given orally. Small animal ultrasound and magnetic resonance imaging were utilized for longitudinal
Directory of Open Access Journals (Sweden)
Guang-ming CHEN
2011-08-01
Full Text Available Objective To explore the effect of continuous hemofiltration(CHF on internal environment and survival rate of severe heatstroke dogs with shock.Methods Sixteen healthy male dogs were randomly divided into heatshock group(HS group,n=8 and continuous hemofiltration group(CHF group,n=8.Severe heatstroke model was established by applying high temperature to whole body,and then the animals were removed from the heating cabin as soon as they presented manifestations of shock.Dogs of HS group were put into an ordinary environment,while dogs of CHF group received CHF treatment.The core temperature(Tc,mean arterial pressure(MAP,blood gas analysis,serum electrolytes and survival rate of dogs in two groups were observed.Results The time from heat exposure to shock was 107.0±28.5min and 111.4±22.2min in HS group and CHF group respectively(t=-0.354,P=0.729.The Tc in CHF group declined to normal level 15 to 30 minitues after CHF treatment,while the Tc in HS group remained at a level higher than that before heat exposure at 90min after shock.The Tc of two groups showed significant difference at each time point after shock(P < 0.01.The MAP of both groups was obviously lowered than that before heatstroke.The MAP of CHF group raised gradually 30 min after treatment,while the MAP of HS group rose very slowly,and it was significantly lower than that of CHF group at each time point after 45min(P < 0.05,P < 0.01.All the dogs in both groups manifested hyperventilation and respiratory alkalosis when shock appeared.After shock,respiratory alkalosis in HS group gradually became metabolic acidosis,with some animals manifested combined metabolic and respiratory acidosis because of respiratory decompensation,while the blood gas levels in CHF group recovered to normal gradually.The blood gas levels of two groups showed significant difference at each time point after shock(P < 0.05,P < 0.01.Hypernatremia,hyperchloraemia and hyperpotassaemia were found in all animals of both
Calculation of expected rates of fisheries‐induced evolution in data‐poor situations
DEFF Research Database (Denmark)
Andersen, Ken Haste
2010-01-01
A central part of an impact assessment of the evolutionary effects of fishing is a calculation of the expected rates of fishing induced by current fishing practice and an evaluation of how alternative fishing patterns may reduce evolutionary impacts of fishing. Here a general size-based framework...... for modeling the demography of fish based on size-based prescriptions of natural mortality, growth, and fishing is presented. Life history theory is used to reduce the necessary parameter set by utilizing relations between parameters making the framework particularly well suited for data-poor situations where...... only the size at maturation or the asymptotic size is known. The framework is applied to perform the modeling part of an evolutionary impact assessment using basic quantitative genetics to calculated expected rates of evolution on size at maturation, growth rate, and investment in gonads. A sensitivity...
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Olivier Le Gac
2015-02-01
Full Text Available The aim of this chart review was to obtain an objective, quantitative assessment of the clinical performance of an implant line used in an implantological office setting. Implants with hydrophilic (INICELL and hydrophobic (TST; both: Thommen Medical AG, Grenchen, Switzerland enossal surfaces were compared and the cumulative implant survival rate was calculated. The data of 1063 patients that received 2918 implants (1337 INICELL, 1581 TST was included. The average follow up time was 2.1 (1.1–5.4 years for INICELL and 4.5 (1.3–5.9 years for TST implants (Thommen Medical AG, Switzerland. In the reported period 7 implants with INICELL (0.5% and 23 TST implants (1.5% failed. This difference was statistically significant. The analysis of cases treated and followed up in a single implantological office for 6 years confirmed the very good clinical outcome that was achieved with both used implant lines. Within the limitations of this retrospective analysis, the overall early failure rate of the hydrophilic implants was significantly lower than that of hydrophobic implants. The use of hydrophilic implants allows the clinician to obtain less early failures, hence the interest of an up-to-date surface for the daily work of an implant practice.
Gac, Olivier Le; Grunder, Ueli
2015-02-05
The aim of this chart review was to obtain an objective, quantitative assessment of the clinical performance of an implant line used in an implantological office setting. Implants with hydrophilic (INICELL) and hydrophobic (TST; both: Thommen Medical AG, Grenchen, Switzerland) enossal surfaces were compared and the cumulative implant survival rate was calculated. The data of 1063 patients that received 2918 implants (1337 INICELL, 1581 TST) was included. The average follow up time was 2.1 (1.1-5.4) years for INICELL and 4.5 (1.3-5.9) years for TST implants (Thommen Medical AG, Switzerland). In the reported period 7 implants with INICELL (0.5%) and 23 TST implants (1.5%) failed. This difference was statistically significant. The analysis of cases treated and followed up in a single implantological office for 6 years confirmed the very good clinical outcome that was achieved with both used implant lines. Within the limitations of this retrospective analysis, the overall early failure rate of the hydrophilic implants was significantly lower than that of hydrophobic implants. The use of hydrophilic implants allows the clinician to obtain less early failures, hence the interest of an up-to-date surface for the daily work of an implant practice.
DEFF Research Database (Denmark)
Blom, M T; Warnier, M J; Bardai, A
2013-01-01
) had comparable survival to ER (75% vs. 78%, OR 0.9 [95% CI: 0.6-1.3]) and to hospital admission (56% vs. 57%, OR 1.0 [0.7-1.4]). However, survival to hospital discharge was significantly lower among OPD patients (21% vs. 33%, OR 0.6 [0.4-0.9]). Multivariate regression analysis among patients who were...... with obstructive pulmonary disease (OPD) have a lower survival rate after OHCA than non-OPD patients. METHODS: We performed a community-based cohort study of 1172 patients with non-traumatic OHCA with ECG-documented VT/VF between 2005 and 2008. We compared survival to emergency room (ER), to hospital admission...... admitted to hospital (OPD: n=100, no OPD: n=561) revealed that OPD was an independent determinant of reduced 30-day survival rate (39% vs. 59%, adjusted OR 0.6 [0.4-1.0, p=0.035]). CONCLUSION: OPD-patients had lower survival rates after OHCA than non-OPD patients. Survival to ER and to hospital admission...
Dose rates from a C-14 source using extrapolation chamber and MC calculations
International Nuclear Information System (INIS)
Borg, J.
1996-05-01
The extrapolation chamber technique and the Monte Carlo (MC) calculation technique based on the EGS4 system have been studied for application for determination of dose rates in a low-energy β radiation field e.g., that from a 14 C source. The extrapolation chamber measurement method is the basic method for determination of dose rates in β radiation fields. Applying a number of correction factors and the stopping power ratio, tissue to air, the measured dose rate in an air volume surrounded by tissue equivalent material is converted into dose to tissue. Various details of the extrapolation chamber measurement method and evaluation procedure have been studied and further developed, and a complete procedure for the experimental determination of dose rates from a 14 C source is presented. A number of correction factors and other parameters used in the evaluation procedure for the measured data have been obtained by MC calculations. The whole extrapolation chamber measurement procedure was simulated using the MC method. The measured dose rates showed an increasing deviation from the MC calculated dose rates as the absorber thickness increased. This indicates that the EGS4 code may have some limitations for transport of very low-energy electrons. i.e., electrons with estimated energies less than 10 - 20 keV. MC calculations of dose to tissue were performed using two models: a cylindrical tissue phantom and a computer model of the extrapolation chamber. The dose to tissue in the extrapolation chamber model showed an additional buildup dose compared to the dose in the tissue model. (au) 10 tabs., 11 ills., 18 refs
Shell model calculations for levels and transition rates in 204Pb and 206Pb
International Nuclear Information System (INIS)
Wang, D.; McEllistrem, M.T.
1990-01-01
Level energies and decay rates of both negative and positive parity levels of 206,204 Pb have been calculated through mixed-configuration shell model calculations using the modified surface delta interaction (MSDI), the Schiffer-True central interaction, and another two-body interaction. These calculations were all carried out with a full six-orbit neutron hole space. The predicted low-lying levels with the MSDI are in excellent agreement with experiments, accounting for the energies, spins, and parities of essentially all levels below 3 MeV excitation energy except known particle-hole collective excitations in both nuclei. Almost all calculated E2 and M1 transition rates are consistent with measured branching ratios for γ-ray decay of excited levels. The comparison of the observed and calculated levels demonstrates the important role played by the neutron-hole i 13/2 configuration in the levels of 204 Pb and 206 Pb, and interprets an apparent discrepancy over the character and energy spacings of 0 + levels in 204 Pb
Clouvas, A; Antonopoulos-Domis, M; Silva, J
2000-01-01
The dose rate conversion factors D/sub CF/ (absorbed dose rate in air per unit activity per unit of soil mass, nGy h/sup -1/ per Bq kg/sup -1/) are calculated 1 m above ground for photon emitters of natural radionuclides uniformly distributed in the soil. Three Monte Carlo codes are used: 1) The MCNP code of Los Alamos; 2) The GEANT code of CERN; and 3) a Monte Carlo code developed in the Nuclear Technology Laboratory of the Aristotle University of Thessaloniki. The accuracy of the Monte Carlo results is tested by the comparison of the unscattered flux obtained by the three Monte Carlo codes with an independent straightforward calculation. All codes and particularly the MCNP calculate accurately the absorbed dose rate in air due to the unscattered radiation. For the total radiation (unscattered plus scattered) the D/sub CF/ values calculated from the three codes are in very good agreement between them. The comparison between these results and the results deduced previously by other authors indicates a good ag...
Energy Technology Data Exchange (ETDEWEB)
Wrede, D E; Dawalibi, H [King Faisal Specialist Hospital and Research Centre, Department of Medical Physics. Riyadh (Saudi Arabia)
1980-01-01
A simple mathematical algorithm is derived from experimental data for dose rates from /sup 137/Cs sources in a finite tissue equivalent medium corresponding to the female pelvis. An analytical expression for a point source of /sup 137/Cs along with a simple numerical integration routine allows for rapid as well as accurate dose rate calculations at points of interest for gynecologic insertions. When compared with theoretical models assuming an infinite unit density medium, the measured dose rates are found to be systematically lower at distances away from a single source; 5 per cent at 2 cm and 10 per cent at 7 cm along the transverse axis. Allowance in the program for print out of dose rates from individual sources to a given point and the feature of source strength modification allows for optimization in terms of increasing the difference in dose rate between reference treatment points and sensitive structures such as the bladder, rectum and colon.
International Nuclear Information System (INIS)
Wrede, D.E.; Dawalibi, H.
1980-01-01
A simple mathematical algorithm is derived from experimental data for dose rates from 137 Cs sources in a finite tissue equivalent medium corresponding to the female pelvis. An analytical expression for a point source of 137 Cs along with a simple numerical integration routine allows for rapid as well as accurate dose rate calculations at points of interest for gynecologic insertions. When compared with theoretical models assuming an infinite unit density medium, the measured dose rates are found to be systematically lower at distances away from a single source; 5 per cent at 2 cm and 10 per cent at 7 cm along the transverse axis. Allowance in the program for print out of dose rates from individual sources to a given point and the feature of source strength modification allows for optimization in terms of increasing the difference in dose rate between reference treatment points and sensitive structures such as the bladder, rectum and colon. (Auth.)
Preliminary calculations of release rates from spent fuel in a tuff repository
International Nuclear Information System (INIS)
Apted, M.J.; O'Connell, W.J.; Lee, K.H.; MacIntyre, A.T.; Ueng, T.S.; Pigford, T.H.; Lee, W.W.L.
1991-01-01
Time-dependent release rates of Tc-99, I-129, Cs-135, and Np-237 have been calculated for wet-drip and moist-continuous release modes from the engineered barrier system of a potential nuclear waste repository in unsaturated tuff, representative of a possible repository at Yucca Mountain in southern Nevada. We describe the modes of water contact and of release of dissolved radionuclides to the surrounding intact rock, and the corresponding calculational models. We list the parameter values adopted, and then present numerical results, conclusions, and recommendations. 21 refs., 5 figs., 2 tabs
Oral cancer incidence and survival rates in the Republic of Ireland, 1994-2009.
Ali, Hala; Sinnott, Sarah-Jo; Corcoran, Paul; Deady, Sandra; Sharp, Linda; Kabir, Zubair
2016-12-20
Oral cancer is a significant public health problem world-wide and exerts high economic, social, psychological, and physical burdens on patients, their families, and on their primary care providers. We set out to describe the changing trends in incidence and survival rates of oral cancer in Ireland between 1994 and 2009. National data on incident oral cancers [ICD 10 codes C01-C06] were obtained from the National Cancer Registry Ireland from 1994 to 2009. We estimated annual percentage change (APC) in oral cancer incidence during 1994-2009 using joinpoint regression software (version 4.2.0.2). The lifetime risk of oral cancer to age 79 was estimated using Irish incidence and population data from 2007 to 2009. Survival rates were also examined using Kaplan-Meier curves and Cox proportional hazard models to explore the influence of several demographic/lifestyle covariates with follow-up to end 2012. Data were obtained on 2,147 oral cancer incident cases. Men accounted for two-thirds of oral cancer cases (n = 1,430). Annual rates in men decreased significantly during 1994-2001 (APC = -4.8 %, 95 % CI: -8.7 to -0.7) and then increased moderately (APC = 2.3 %, 95 % CI: -0.9 to 5.6). In contrast, annual incidence increased significantly in women throughout the study period (APC = 3.2 %, 95 % CI: 1.9 to 4.6). There was an elevated risk of death among oral cancer patients who were: older than 60 years of age; smokers; unemployed or retired; those living in the most deprived areas; and those whose tumour was sited in the base of the tongue. Being married and diagnosed in more recent years were associated with reduced risk of death. Oral cancer increased significantly in both sexes between 1999 and 2009 in Ireland. Our analyses demonstrate the influence of measured factors such as smoking, time of diagnosis and age on observed trends. Unmeasured factors such as alcohol use, HPV and dietary factors may also be contributing to increased trends. Several of
Comparison of measured and calculated reaction rate distributions in an scwr-like test lattice
Energy Technology Data Exchange (ETDEWEB)
Raetz, Dominik, E-mail: dominik.raetz@psi.ch [Paul Scherrer Institut, CH-5232 Villigen PSI (Switzerland); Jordan, Kelly A., E-mail: kelly.jordan@psi.ch [Paul Scherrer Institut, CH-5232 Villigen PSI (Switzerland); Murphy, Michael F., E-mail: mike.murphy@psi.ch [Paul Scherrer Institut, CH-5232 Villigen PSI (Switzerland); Perret, Gregory, E-mail: gregory.perret@psi.ch [Paul Scherrer Institut, CH-5232 Villigen PSI (Switzerland); Chawla, Rakesh, E-mail: rakesh.chawla@psi.ch [Paul Scherrer Institut, CH-5232 Villigen PSI (Switzerland); Ecole Polytechnique Federale de Lausanne (EPFL), CH-1015 Lausanne, EPFL (Switzerland)
2011-04-15
High resolution gamma-ray spectroscopy measurements were performed on 61 rods of an SCWR-like fuel lattice, after irradiation in the central test zone of the PROTEUS zero-power research reactor at the Paul Scherrer Institute in Switzerland. The derived reaction rates are the capture rate in {sup 238}U (C{sub 8}) and the total fission rate (F{sub tot}), and also the reaction rate ratio C{sub 8}/F{sub tot}. Each of these has been mapped rod-wise on the lattice and compared to calculated results from whole-reactor Monte Carlo simulations with MCNPX. Ratios of calculated to experimental values (C/E's) have been assessed for the C{sub 8}, F{sub tot} and C{sub 8}/F{sub tot} distributions across the lattice. These C/E's show excellent agreement between the calculations and the measurements. For the {sup 238}U capture rate distribution, the 1{sigma} level in the comparisons corresponds to an uncertainty of {+-}0.8%, while for the total fission rate the corresponding value is {+-}0.4%. The uncertainty for C{sub 8}/F{sub tot}, assessed as a reaction rate ratio characterizing each individual rod position in the test lattice, is significantly higher at {+-}2.2%. To determine the reproducibility of these results, the measurements were performed twice, once in 2006 and again in 2009. The agreement between these two measurement sets is within the respective statistical uncertainties.
Energy Technology Data Exchange (ETDEWEB)
Simone, Angela; Kolarik, Jakub; Olesen, Bjarne W. [ICIEE/BYG, Technical University of Denmark (Denmark); Iwamatsu, Toshiya [Faculty of Urban Environmental Science, Tokyo Metropolitan University (Japan); Asada, Hideo [Architech Consulting Co., Tokyo (Japan); Dovjak, Mateja [Faculty of Civil and Geodetic Engineering, University of Ljubljana (Slovenia); Schellen, Lisje [Eindhoven University of Technology, Faculty of Architecture Building and Planning (Netherlands); Shukuya, Masanori [Laboratory of Building Environment, Tokyo City University, Yokohama (Japan)
2011-01-15
Application of the exergy concept to research on the built environment is a relatively new approach. It helps to optimize climate conditioning systems so that they meet the requirements of sustainable building design. As the building should provide a healthy and comfortable environment for its occupants, it is reasonable to consider both the exergy flows in building and those within the human body. Until now, no data have been available on the relation between human-body exergy consumption rates and subjectively assessed thermal sensation. The objective of the present work was to relate thermal sensation data, from earlier thermal comfort studies, to calculated human-body exergy consumption rates. The results show that the minimum human body exergy consumption rate is associated with thermal sensation votes close to thermal neutrality, tending to the slightly cool side of thermal sensation. Generally, the relationship between air temperature and the exergy consumption rate, as a first approximation, shows an increasing trend. Taking account of both convective and radiative heat exchange between the human body and the surrounding environment by using the calculated operative temperature, exergy consumption rates increase as the operative temperature increases above 24 C or decreases below 22 C. With the data available so far, a second-order polynomial relationship between thermal sensation and the exergy consumption rate was established. (author)
Directory of Open Access Journals (Sweden)
Julian A Tyne
Full Text Available Reliable population estimates are critical to implement effective management strategies. The Hawai'i Island spinner dolphin (Stenella longirostris is a genetically distinct stock that displays a rigid daily behavioural pattern, foraging offshore at night and resting in sheltered bays during the day. Consequently, they are exposed to frequent human interactions and disturbance. We estimated population parameters of this spinner dolphin stock using a systematic sampling design and capture-recapture models. From September 2010 to August 2011, boat-based photo-identification surveys were undertaken monthly over 132 days (>1,150 hours of effort; >100,000 dorsal fin images in the four main resting bays along the Kona Coast, Hawai'i Island. All images were graded according to photographic quality and distinctiveness. Over 32,000 images were included in the analyses, from which 607 distinctive individuals were catalogued and 214 were highly distinctive. Two independent estimates of the proportion of highly distinctive individuals in the population were not significantly different (p = 0.68. Individual heterogeneity and time variation in capture probabilities were strongly indicated for these data; therefore capture-recapture models allowing for these variations were used. The estimated annual apparent survival rate (product of true survival and permanent emigration was 0.97 SE ± 0.05. Open and closed capture-recapture models for the highly distinctive individuals photographed at least once each month produced similar abundance estimates. An estimate of 221 ± 4.3 SE highly distinctive spinner dolphins, resulted in a total abundance of 631 ± 60.1 SE, (95% CI 524-761 spinner dolphins in the Hawai'i Island stock, which is lower than previous estimates. When this abundance estimate is considered alongside the rigid daily behavioural pattern, genetic distinctiveness, and the ease of human access to spinner dolphins in their preferred resting habitats, this
Effects of pond salinization on survival rate of amphibian hosts infected with the chytrid fungus.
Stockwell, Michelle Pirrie; Storrie, Lachlan James; Pollard, Carla Jean; Clulow, John; Mahony, Michael Joseph
2015-04-01
The chytrid fungus Batrachochytrium dendrobatidis has been implicated in the decline and extinction of amphibian populations worldwide, but management options are limited. Recent studies show that sodium chloride (NaCl) has fungicidal properties that reduce the mortality rates of infected hosts in captivity. We investigated whether similar results can be obtained by adding salt to water bodies in the field. We increased the salinity of 8 water bodies to 2 or 4 ppt and left an additional 4 water bodies with close to 0 ppt and monitored salinity for 18 months. Captively bred tadpoles of green and golden bell frog (Litoria aurea) were released into each water body and their development, levels of B. dendrobatidis infection, and survival were monitored at 1, 4, and 12 months. The effect of salt on the abundance of nontarget organisms was also investigated in before and after style analyses. Salinities remained constant over time with little intervention. Hosts in water bodies with 4 ppt salt had a significantly lower prevalence of chytrid infection and higher survival, following metamorphosis, than hosts in 0 ppt salt. Tadpoles in the 4 ppt group were smaller in length after 1 month in the release site than those in the 0 and 2 ppt groups, but after metamorphosis body size in all water bodies was similar . In water bodies with 4 ppt salt, the abundance of dwarf tree frogs (Litoria fallax), dragonfly larvae, and damselfly larvae was lower than in water bodies with 0 and 2 ppt salt, which could have knock-on effects for community structure. Based on our results, salt may be an effective field-based B. dendrobatidis mitigation tool for lentic amphibians that could contribute to the conservation of numerous susceptible species. However, as in all conservation efforts, these benefits need to be weighed against negative effects on both target and nontarget organisms. © 2014 Society for Conservation Biology.
Rate maximum calculation of Dpa in CNA-II pressure vessel
International Nuclear Information System (INIS)
Mascitti, J. A
2012-01-01
The maximum dpa rate was calculated for the reactor in the following state: fresh fuel, no Xenon, a Boron concentration of 15.3 ppm, critical state, its control rods in the criticality position, hot, at full power (2160 MW). It was determined that the maximum dpa rate under such conditions is 3.54(2)x10 12 s -1 and it is located in the positions corresponding to θ=210 o in the azimuthal direction, and z=20 cm and -60 cm respectively in the axial direction, considering the calculation mesh centered at half height of the fuel element (FE) active length. The dpa rate spectrum was determined as well as the contribution to it for 4 energy groups: a thermal group, two epithermal groups and a fast one. The maximum dpa rate considering the photo-neutrons production from (γ, n) reaction in the heavy water of coolant and moderator was 3.93(4)x10 12 s -1 that is 11% greater than the obtained without photo-neutrons. This verified significant difference between both cases, suggest that photo-neutrons in large heavy water reactors such as CNA-II should not be ignored. The maximum DPA rate in the first mm of the reactor pressure vessel was calculated too and it was obtained a value of 4.22(6)x10 12 s -1 . It should be added that the calculation was carried out with the reactor complete accurate model, with no approximations in spatial or energy variables. Each value has, between parentheses, a percentage relative error representing the statistical uncertainty due to the probabilistic Monte Carlo method used to estimate it. More representative values may be obtained with this method if equilibrium burn-up distribution is used (author)
Stanley, Thomas R.; Aldridge, Cameron L.; Joanne Saher,; Theresa Childers,
2015-01-01
The Gunnison Sage-Grouse (Centrocercus minimus) is a species of conservation concern and is a candidate for listing under the U.S. Endangered Species Act because of substantial declines in populations from historic levels. It is thought that loss, fragmentation, and deterioration of sagebrush (Artemisia spp.) habitat have contributed to the decline and isolation of this species into seven geographically distinct subpopulations. Nest survival is known to be a primary driver of demography of Greater Sage-Grouse (C. urophasianus), but no unbiased estimates of daily nest survival rates (hereafter nest survival) exist for Gunnison Sage-Grouse or published studies identifying factors that influence nest survival. We estimated nest survival of Gunnison Sage-Grouse for the western portion of Colorado's Gunnison Basin subpopulation, and assessed the effects and relative importance of local- and landscape-scale habitat characteristics on nest survival. Our top performing model was one that allowed variation in nest survival among areas, suggesting a larger landscape-area effect. Overall nest success during a 38-day nesting period (egg-laying plus incubation) was 50% (daily survival rate; SE = 0.982 [0.003]), which is higher than previous estimates for Gunnison Sage-Grouse and generally higher than published for the closely related Greater Sage-Grouse. We did not find strong evidence that local-scale habitat variables were better predictors of nest survival than landscape-scale predictors, nor did we find strong evidence that any of the habitat variables we measured were good predictors of nest survival. Nest success of Gunnison Sage-Grouse in the western portion of the Gunnison Basin was higher than previously believed.
Flouri, Irini; Markatseli, Theodora E; Voulgari, Paraskevi V; Boki, Kyriaki A; Papadopoulos, Ioannis; Settas, Loukas; Zisopoulos, Dimitrios; Skopouli, Fotini N; Iliopoulos, Alexios; Bertsias, George K; Geborek, Pierre; Drosos, Alexandros A; Boumpas, Dimitrios T; Sidiropoulos, Prodromos
2014-02-01
To compare effectiveness, drug survival, and safety between infliximab, adalimumab, and etanercept, in a nationwide cohort of rheumatoid arthritis (RA) patients. This study is a prospective cohort study of 1208 active RA patients. Effectiveness, drug survival, and serious adverse events during entire follow-up (median 2.9 years) were monitored. EULAR and CDAI responses were comparable between the three agents (EULAR good/moderate responses at 12 months ranged 76-79%). At 12 months, 15-23% achieved remission. For adalimumab and etanercept, adjusted hazard rate (HR) for EULAR/ACR remission (reference: infliximab) was 2.7 and 2.1 (95% confidence interval was 1.7-4.1 and 1.3-3.4, respectively); males (HR 1.6; 1.1-2.4), use of glucocorticoids (HR 2.0; 1.3-3.0), and swollen joint count >7 (HR 0.36; 0.24-0.55) were independent predictors. Five-year drug survival was 31%, 43%, and 49% for infliximab, adalimumab, and etanercept, respectively (p = 0.010). Infliximab was associated with significantly more withdrawals due to adverse events. Disease activity, CRP, and use of glucocorticoids predicted efficacy-related drug survival; age, use of methotrexate, and prior DMARDs failures predicted safety-related survival. Risk for serious infections was lower with adalimumab (odds ratio [OR] 0.62; 0.38-1.00) or etanercept (OR 0.39; 0.21-0.72) than infliximab, independent of the effects of age (OR 1.65; 1.37-2.00 per 10 years), tender joint count >10 (OR 1.86; 1.21-2.86), and glucocorticoids >35mg/week (OR 1.83; 1.12-2.99). Response rates were comparable among anti-TNF agents. Overall, 5-year drug survival was below 50%, with infliximab demonstrating increased safety-related discontinuations. Remission rates are low in clinical practice. Strategies to increase effectiveness and long-term survival of anti-TNF agents in RA are needed. Copyright © 2014 Elsevier Inc. All rights reserved.
Draper, E. S.; Zeitlin, J.; Fenton, A. C.; Weber, T.; Gerrits, J.; Martens, G.; Misselwitz, B.; Breart, G.
Objective: To investigate the variation in the survival rate and the mortality rates for very preterm infants across Europe. Design: A prospective birth cohort of very preterm infants for 10 geographically defined European regions during 2003, followed to discharge home from hospital. Participants:
Calculation of the soft error rate of submicron CMOS logic circuits
International Nuclear Information System (INIS)
Juhnke, T.; Klar, H.
1995-01-01
A method to calculate the soft error rate (SER) of CMOS logic circuits with dynamic pipeline registers is described. This method takes into account charge collection by drift and diffusion. The method is verified by comparison of calculated SER's to measurement results. Using this method, the SER of a highly pipelined multiplier is calculated as a function of supply voltage for a 0.6 microm, 0.3 microm, and 0.12 microm technology, respectively. It has been found that the SER of such highly pipelined submicron CMOS circuits may become too high so that countermeasures have to be taken. Since the SER greatly increases with decreasing supply voltage, low-power/low-voltage circuits may show more than eight times the SER for half the normal supply voltage as compared to conventional designs
Decay heat rates calculated using ORIGEN-S and CINDER10 with common data libraries
International Nuclear Information System (INIS)
Brady, M.C.; Hermann, O.W.; Beard, C.A.; Bohnhoff, W.J.; England, T.R.
1991-01-01
A set of two benchmark problems were proposed as part of an international comparison of decay heat codes. Problem specifications included explicit fission-yield, decay and capture data libraries to be used in the calculations. This paper describes the results obtained using these common data to perform the benchmark calculations with two popular depletion codes, ORIGEN-S and CINDER10. Short descriptions of the methods used by each of these codes are also presented. Results from other contributors to the international comparison are discussed briefly. This comparison of decay heat codes using common data libraries demonstrates that discrepant results in calculated decay heat rates are the result of differences in the nuclear data input to the codes and not the method of solution. 15 refs., 2 figs., 8 tabs
International Nuclear Information System (INIS)
Oishi, Koji; Minami, Kiyoshi; Ikeda, Yujiro; Kosako, Kazuaki; Nakamura, Tomoo
1991-01-01
A concrete assembly was irradiated by D-T neutrons for 10 h, and dose rate measurement one day after shutdown has been carried out in order to provide a guide line for selection studies of low activation concrete. The experimental results were analyzed by the two dimensional calculation code DOT3.5 with its related nuclear data library GICX40 based on ENDF/B-III, however disagreement between experiment and calculation was observed in the deeper detector positions. Calculations were also performed using the nuclear data library based on ENDF/B-IV, and agreement within experimental errors was obtained at all detector positions. Selection studies for low activation concrete were performed using this nuclear data library. As a result, it was found that limestone concrete exhibited excellent properties as a low activation concrete in fusion facilities. (orig.)
Extended calculations of energies, transition rates, and lifetimes for F-like Kr XXVIII
Zhang, C. Y.; Si, R.; Yao, K.; Gu, M. F.; Wang, K.; Chen, C. Y.
2018-02-01
The excitation energies, lifetimes, wavelengths and E1, E2, M1 and M2 transition rates for the lowest 389 levels of the 2l7, 2l63l‧, 2l64l‧, and 2l65l‧ configurations from second-order many-body perturbation theory (MBPT) calculations, and the results for the lowest 200 states of the 2l7, 2l63l‧, and 2l64l‧ configurations from multi-configuration Dirac-Hartree-Fock (MCDHF) calculations in F-like Kr XXVIII are presented in this work. The relative differences between our two sets of level energies are mostly within 0.005% for the lowest 200 levels. Comparisons are made with experimental and other available theoretical results to assess the reliability and accuracy of the present calculations. We believe them to be the most complete and accurate results for Kr XXVIII at present.
Hredzák, R; Ostró, A; Zdilová, Viera; Maracek, I; Kacmárik, J
2006-03-01
The aim of the study was to determine the relationship between the rate of cooling of eight-cell mouse embryos to the temperature of liquid nitrogen (-196 degrees C) and their developmental capacity after thawing on the basis of their ability to leave the zona pellucida ('hatching') during in vitro culturing. Eight-cell embryos were obtained from superovulated female mice and divided into three experimental and one control group. Embryos from the experimental groups were cryopreserved by the vitrification method using ethylene glycol as cryoprotectant. The vitrification protocols used in the study differed in the rate of cooling of the cryoprotectant solution. Embryos from the first group were frozen in conventional 0.25-ml plastic straws, those from the second group in pipetting 'tips', and embryos from the third group, placed in vitrification solution, were introduced dropwise directly into liquid nitrogen. The control group of embryos was cultured in vitro without freezing in a culturing medium in an environment consisting of 95% air and 5% CO2. The developmental capacity of thawed embryos was assessed on the basis of their ability to leave the zona pellucida ('hatching') after three days of in vitro culturing. In the control group 95.1% of embryos 'hatched'. A significantly higher number of embryos that 'hatched' after thawing was observed in the group introduced dropwise directly into liquid nitrogen (60.0%) compared to the group frozen in pipetting 'tips' (37.9%). The group frozen in straws yielded significantly the lowest proportion of 'hatching' embryos (8.1%). These results showed that increasing cooling rates during vitrification of embryos improved their survival.
Calculation of hydrogen outgassing rate of LHD by recombination limited model
International Nuclear Information System (INIS)
Akaishi, K.; Nakasuga, M.
2002-04-01
To simulate hydrogen outgassing in the plasma vacuum vessel of LHD, the recombination limited model is presented, where the time evolution of hydrogen concentration in the wall of the plasma vacuum vessel is described by a one-dimensional diffusion equation. The hydrogen outgassing rates when the plasma vacuum vessel is pumped down at room temperature and baked at 100 degC are calculated as a function of pumping time. The calculation shows that the hydrogen outgassing rate of the plasma vacuum vessel can be reduced at least by one order of magnitude due to pumping and baking. This prediction is consistent with the recent result of outgassing reduction observed in the pumping-down and baking of the plasma vacuum vessel in LHD. (author)
External dose-rate conversion factors for calculation of dose to the public
Energy Technology Data Exchange (ETDEWEB)
1988-07-01
This report presents a tabulation of dose-rate conversion factors for external exposure to photons and electrons emitted by radionuclides in the environment. This report was prepared in conjunction with criteria for limiting dose equivalents to members of the public from operations of the US Department of Energy (DOE). The dose-rate conversion factors are provided for use by the DOE and its contractors in performing calculations of external dose equivalents to members of the public. The dose-rate conversion factors for external exposure to photons and electrons presented in this report are based on a methodology developed at Oak Ridge National Laboratory. However, some adjustments of the previously documented methodology have been made in obtaining the dose-rate conversion factors in this report. 42 refs., 1 fig., 4 tabs.
Results of a bench mark test on the crack opening and leak rate calculation
International Nuclear Information System (INIS)
Grebner, H.
1995-01-01
Results of a bench mark test on the standard problem calculation of crack opening and leak rate in piping components are presented. The bench mark test is based on two experiments performed in phase III of the German HDR safety program. The pipe sections considered in these experiments were a straight pipe with an 80 mm diameter containing a circumferential wall penetrating crack and a pipe branch DN 100/DN 25 with a crack in the weldment between the nozzle and the main pipe. Both test pieces were made of austenitic steel and were loaded by internal pressure and bending moment. For the evaluation of the crack opening either analytical methods or estimation schemes or the finite element method were used, while leak rates were calculated by means of two-phase flow methods. The compilation of the results shows very large scatter bands in general, with deviations between calculated and measured values of up to some one hundred percent. Reasons for this behaviour are uncertainties in the measured data and their evaluation as well as the different methods of calculation and their uncertainties. (author)
Preliminary results on food consumption rates for off-site dose calculation of nuclear power plants
International Nuclear Information System (INIS)
Lee, Gab Bock; Chung, Yang Geun; Bang, Sun Young; Kang, Duk Won
2005-01-01
The Internal dose by food consumption mostly account for radiological dose of public around nuclear power plants(NPP). But, food consumption rate applied to off-site dose calculation in Korea which is the result of field investigation around Kori NPP by the KAERI in 1988. is not reflected of the latest dietary characteristics. The Ministry of Health and Welfare Affairs has investigated the food and nutrition of nations every 3 years based on the Law of National Health Improvement. To update the food consumption rates of the maximum individual, the analysis of the national food investigation results and field surveys around nuclear power plant sites have been carried out
Assessments of fluid friction factors for use in leak rate calculations
Energy Technology Data Exchange (ETDEWEB)
Chivers, T.C. [Berkeley Technology Centre, Glos (United Kingdom)
1997-04-01
Leak before Break procedures require estimates of leakage, and these in turn need fluid friction to be assessed. In this paper available data on flow rates through idealized and real crack geometries are reviewed in terms of a single friction factor k It is shown that for {lambda} < 1 flow rates can be bounded using correlations in terms of surface R{sub a} values. For {lambda} > 1 the database is less precise, but {lambda} {approx} 4 is an upper bound, hence in this region flow calculations can be assessed using 1 < {lambda} < 4.
Swigris, Jeffrey J.; Swick, Jeff; Wamboldt, Frederick S.; Sprunger, David; du Bois, Roland; Fischer, Aryeh; Cosgrove, Gregory P.; Frankel, Stephen K.; Fernandez-Perez, Evans R.; Kervitsky, Dolly; Brown, Kevin K.
2009-01-01
Background: In patients with idiopathic pulmonary fibrosis (IPF), our objectives were to identify predictors of abnormal heart rate recovery (HRR) at 1 min after completion of a 6-min walk test (6MWT) [HRR1] and 2 min after completion of a 6MWT (HRR2), and to determine whether abnormal HRR predicts mortality. Methods: From 2003 to 2008, we identified IPF patients who had been evaluated at our center (n = 76) with a pulmonary physiologic examination and the 6MWT. We used logistic regression to identify predictors of abnormal HRR, the product-limit method to compare survival in the sample stratified on HRR, and Cox proportional hazards analysis to estimate the prognostic capability of abnormal HRR. Results: Cutoff values were 13 beats for abnormal HRR1 and 22 beats for HRR2. In a multivariable model, predictors of abnormal HRR1 were diffusing capacity of the lung for carbon monoxide (odds ratio [OR], 0.4 per 10% predicted; 95% confidence interval [CI], 0.2 to 0.7; p = 0.003), change in heart rate from baseline to maximum (OR, 0.9; 95% CI, 0.8 to 0.97; p = 0.01), and having a right ventricular systolic pressure > 35 mm Hg as determined by transthoracic echocardiogram (OR, 12.7; 95% CI, 2.0 to 79.7; p = 0.01). Subjects with an abnormal HRR had significantly worse survival than subjects with a normal HRR (for HRR1, p = 0.0007 [log-rank test]; for HRR2, p = 0.03 [log-rank test]); these results held for the subgroup of 30 subjects without resting pulmonary hypertension (HRR1, p = 0.04 [log-rank test]). Among several candidate variables, abnormal HRR1 appeared to be the most potent predictor of mortality (hazard ratio, 5.2; 95% CI, 1.8 to 15.2; p = 0.004). Conclusion: Abnormal HRR after 6MWT predicts mortality in IPF patients. Research is needed to confirm these findings prospectively and to examine the mechanisms of HRR in IPF patients. PMID:19395579
Effect of Different Medium on Survival Rate and Growth of Chironomus sp. Larvae
Directory of Open Access Journals (Sweden)
. Widanarni
2007-07-01
Full Text Available In the ornamental fish and fish for food culture, feeding by natural feed is very suitable since they are easy to digest and their size is suitable with to larval mouth. One of natural foods is blood worm Chironomus sp. larvae that has high protein content (till 65.2% of protein. Until now, blood worm is obtained from nature and their stock depends on the weather. That problem may be overcome by culturing blood worm in appropriate culture medium. Naturally, Chironomus sp. grows well in the water containing sago waste. This study was carried out to examine the growth of Chironomus sp. reared in the medium containing mud, solid sago waste, solid tapioca wastes and water with no waste in depth of 0.5 cm. After 35-day rearing, survival rate of Chironomus sp was different among the treatments, while growth in length was similar. The best survival rate, 58.93% was obtained in the media containing solid sago waste. Keywords: Chironomus, blood worm, sago waste, tapioca waste ABSTRAK Dalam usaha budidaya ikan hias maupun ikan konsumsi, pemberian pakan alami sangat cocok karena mudah dicerna dan sesuai dengan bukaan mulut larva. Salah satu contoh pakan alami adalah Chironomus sp. (blood worm yang mempunyai kandungan protein mencapai 65,2%. Selama ini cacing darah diperoleh dari alam dan suplainya tergantung pada kondisi musim. Hal ini mungkin dapat diatasi dengan membudidayakan cacing darah dengan media yang sesuai sebagai tempat hidupnya. Secara alami, Chironomus sp. dapat tumbuh dan berkembang dengan baik pada limbah sagu. Penelitian ini dilakukan untuk mengetahui pertumbuhan Chironomus sp. yang dipelihara pada media berupa lumpur, limbah sagu padat, limbah tapioka padat dan air tanpa limbah dengan ketebalan media 0,5 cm. Setelah 35 hari masa pemeliharaan, diketahui bahwa penggunaan media limbah padat sagu, limbah padat tapioka, lumpur dan air tanpa limbah pada pemeliharaan Chironomus sp. masing-masing menghasilkan tingkat
2013-01-08
... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Quarterly IRS Interest Rates... the public of the quarterly Internal Revenue Service interest rates used to calculate interest on... beginning January 1, 2013, the interest rates for [[Page 1223
Calculation of neutron and gamma-ray flux-to-dose-rate conversion factors
International Nuclear Information System (INIS)
Kwon, S.G.; Lee, S.Y.; Yook, C.C.
1981-01-01
This paper presents flux-to-dose-rate conversion factors for neutrons and gamma rays based on the American National Standard Institute (ANSI) N666. These data are used to calculate the dose rate distribution of neutron and gamma ray in radiation fields. Neutron flux-to-dose-rate conversion factors for energies from 2.5 x 10 -8 to 20 MeV are presented; the corresponding energy range for gamma rays is 0.01 to 15 MeV. Flux-to-dose-rate conversion factors were calculated, under the assumption that radiation energy distribution has nonlinearity in the phantom, have different meaning from those values obtained by monoenergetic radiation. Especially, these values were determined with the cross section library. The flux-to-dose-rate conversion factors obtained in this work were in a good agreement to the values presented by ANSI. Those data will be useful for the radiation shielding analysis and the radiation dosimetry in the case of continuous energy distributions. (author)
Calculation of nuclear-spin-relaxation rate for spin-polarized atomic hydrogen
International Nuclear Information System (INIS)
Ahn, R.M.C.; Eijnde, J.P.H.W.V.; Verhaar, B.J.
1983-01-01
Approximations introduced in previous calculations of spin relaxation for spin-polarized atomic hydrogen are investigated by carrying out a more exact coupled-channel calculation. With the exception of the high-temperature approximation, the approximations turn out to be justified up to the 10 -3 level of accuracy. It is shown that at the lowest temperatures for which experimental data are available, the high-temperature limit underestimates relaxation rates by a factor of up to 2. For a comparison with experimental data it is also of interest to pay attention to the expression for the atomic hydrogen relaxation rates in terms of transition amplitudes for two-particle collisions. Discrepancies by a factor of 2 among previous derivations of relaxation rates are pointed out. To shed light on these discrepancies we present two alternative derivations in which special attention is paid to identical-particle aspects. Comparing with experiment, we find our theoretical volume relaxation rate to be in better agreement with measured values than that obtained by other groups. The theoretical surface relaxation rate, however, still shows a discrepancy with experiment by a factor of order 50
Arbib, Zouhayr; de Godos Crespo, Ignacio; Corona, Enrique Lara; Rogalla, Frank
2017-06-01
Microalgae culture in high rate algae ponds (HRAP) is an environmentally friendly technology for wastewater treatment. However, for the implementation of these systems, a better understanding of the oxygenation potential and the influence of climate conditions is required. In this work, the rates of oxygen production, consumption, and exchange with the atmosphere were calculated under varying conditions of solar irradiance and dilution rate during six months of operation in a real scale unit. This analysis allowed determining the biological response of these dynamic systems. The rates of oxygen consumption measured were considerably higher than the values calculated based on the organic loading rate. The response to light intensity in terms of oxygen production in the bioreactor was described with one of the models proposed for microalgae culture in dense concentrations. This model is based on the availability of light inside the culture and the specific response of microalgae to this parameter. The specific response to solar radiation intensity showed a reasonable stability in spite of the fluctuations due to meteorological conditions. The methodology developed is a useful tool for optimization and prediction of the performance of these systems.
Calculation of fluence rate distributions in a pre design clinical facility for BNCT at the LFR
International Nuclear Information System (INIS)
Peeters, T.T.J.M.; Freudenreich, W.E.
1995-12-01
In a previous study [1], it was demonstrated that the creation of a thermal neutron facility for clinical BNCT in the LFR is feasible. Monte Carlo calculations had shown that the neutron fluence rates and gamma dose rates at the detector position of a model representing a first outline of a clinical facility met all requirements that are necessary for clinical BNCT. In order to gain more information about the neutron fluence rates at several positions, a second step is required. Calculations have been performed for the free beam and for a tumour bearing phantom at 5 cm and 10 cm distance from the irradiation window. Due to thermalization and back scattering, the thermal fluence rates in the tumour at 5 and 10 cm distance from the bismuth shield appeared to be approximately twice as high as the thermal fluence rates in the free beam at the corresponding positions of 5 to 6 cm and 10 to 11 cm from the irradiation window. (orig.)
Survival analysis approach to account for non-exponential decay rate effects in lifetime experiments
Energy Technology Data Exchange (ETDEWEB)
Coakley, K.J., E-mail: kevincoakley@nist.gov [National Institute of Standards and Technology, 325 Broadway, Boulder, CO 80305 (United States); Dewey, M.S.; Huber, M.G. [National Institute of Standards and Technology, 100 Bureau Drive, Stop 8461, Gaithersburg, MD 20899 (United States); Huffer, C.R.; Huffman, P.R. [North Carolina State University, 2401 Stinson Drive, Box 8202, Raleigh, NC 27695 (United States); Triangle Universities Nuclear Laboratory, 116 Science Drive, Box 90308, Durham, NC 27708 (United States); Marley, D.E. [National Institute of Standards and Technology, 100 Bureau Drive, Stop 8461, Gaithersburg, MD 20899 (United States); North Carolina State University, 2401 Stinson Drive, Box 8202, Raleigh, NC 27695 (United States); Mumm, H.P. [National Institute of Standards and Technology, 100 Bureau Drive, Stop 8461, Gaithersburg, MD 20899 (United States); O' Shaughnessy, C.M. [University of North Carolina at Chapel Hill, 120 E. Cameron Ave., CB #3255, Chapel Hill, NC 27599 (United States); Triangle Universities Nuclear Laboratory, 116 Science Drive, Box 90308, Durham, NC 27708 (United States); Schelhammer, K.W. [North Carolina State University, 2401 Stinson Drive, Box 8202, Raleigh, NC 27695 (United States); Triangle Universities Nuclear Laboratory, 116 Science Drive, Box 90308, Durham, NC 27708 (United States); Thompson, A.K.; Yue, A.T. [National Institute of Standards and Technology, 100 Bureau Drive, Stop 8461, Gaithersburg, MD 20899 (United States)
2016-03-21
In experiments that measure the lifetime of trapped particles, in addition to loss mechanisms with exponential survival probability functions, particles can be lost by mechanisms with non-exponential survival probability functions. Failure to account for such loss mechanisms produces systematic measurement error and associated systematic uncertainties in these measurements. In this work, we develop a general competing risks survival analysis method to account for the joint effect of loss mechanisms with either exponential or non-exponential survival probability functions, and a method to quantify the size of systematic effects and associated uncertainties for lifetime estimates. As a case study, we apply our survival analysis formalism and method to the Ultra Cold Neutron lifetime experiment at NIST. In this experiment, neutrons can escape a magnetic trap before they decay due to a wall loss mechanism with an associated non-exponential survival probability function.
Survival analysis approach to account for non-exponential decay rate effects in lifetime experiments
International Nuclear Information System (INIS)
Coakley, K.J.; Dewey, M.S.; Huber, M.G.; Huffer, C.R.; Huffman, P.R.; Marley, D.E.; Mumm, H.P.; O'Shaughnessy, C.M.; Schelhammer, K.W.; Thompson, A.K.; Yue, A.T.
2016-01-01
In experiments that measure the lifetime of trapped particles, in addition to loss mechanisms with exponential survival probability functions, particles can be lost by mechanisms with non-exponential survival probability functions. Failure to account for such loss mechanisms produces systematic measurement error and associated systematic uncertainties in these measurements. In this work, we develop a general competing risks survival analysis method to account for the joint effect of loss mechanisms with either exponential or non-exponential survival probability functions, and a method to quantify the size of systematic effects and associated uncertainties for lifetime estimates. As a case study, we apply our survival analysis formalism and method to the Ultra Cold Neutron lifetime experiment at NIST. In this experiment, neutrons can escape a magnetic trap before they decay due to a wall loss mechanism with an associated non-exponential survival probability function.
International Nuclear Information System (INIS)
Gomes, Renato G.; Rebello, Wilson F.; Vellozo, Sergio O.; Junior, Luis M.; Vital, Helio C.; Rusin, Tiago; Silva, Ademir X.
2013-01-01
MCNPX simulations have been performed in order to calculate dose rates as well as spectra along the four experimental channels of the gamma irradiating facility at the Technology Center of the Brazilian Army (CTEx). Safety, operational and research requirements have led to the need to determine both the magnitude and spectra of the leaking gamma fluxes. The CTEx experimental facility is cavity type with a moveable set of 28 horizontally positioned rods, filled with Cesium-137 chloride and doubly encased in stainless steel that yields an approximately plane 42 kCi-source that provides a maximum dose rate of about 1.5 kG/h into two irradiating chambers. The channels are intended for irradiation tests outside facility. They would allow larger samples to be exposed to lower gamma dose rates under controlled conditions. Dose rates have been calculated for several positions inside the channels as well as at their exits. In addition, for purposes related to the safety of operators and personnel, the angles submitted by the exiting beams have also been evaluated as they spread when leaving the channels. All calculations have been performed by using a computational model of the CTEx facility that allows its characteristics and operation to be accurately simulated by using the Monte Carlo Method. Virtual dosimeters filled with Fricke (ferrous sulfate) were modeled and positioned throughout 2 vertical channels (top and bottom) and 2 horizontal ones (front and back) in order to map dose rates and gamma spectrum distributions. The calculations revealed exiting collimated beams in the order of tenths of Grays per minute as compared to the maximum 25 Gy / min dose rate in the irradiator chamber. In addition, the beams leaving the two vertical channels were found to exhibit a widespread cone-shaped distribution with aperture angle ranging around 85 deg. The data calculated in this work are intended for use in the design of optimized experiments (better positioning of samples and
Firms Started As Franchises Have Lower Survival Rates Than Independent Small Business Startups
Timothy Bates
1994-01-01
Aspiring entrepreneurs choosing to become franchisees certainly expect to improve their chances of survival during the turbulent early years of business startup and operation. Alignment with a franchiser parent company offers the franchisee managerial assistance, access to financial capital, and access to markets via the right to utilize the parent company trademark. This study examines survival patterns among franchise and nonfranchise small firms started between 1984 and 1987: survival thro...
Hinson, K R; Benson, E P; Zungoli, P A; Bridges, W C; Ellis, B R
2016-12-01
Few studies have addressed the efficacy of insecticides used against eggs and first-instar nymphs of the bed bug, Cimex lectularius L. (Hemiptera: Cimicidae). Insect eggs are often resistant to insecticides; therefore, information on which products are effective is important. We evaluated the efficacy of four commonly used insecticide sprays applied directly to bed bug eggs. We also evaluated the efficacy of these insecticides to first-instar nymphs exposed to residuals resulting from directly spraying eggs. Temprid SC (beta-cyfluthrin, imidacloprid) was the most effective insecticide at preventing egg hatch (13% hatch rate) for pyrethroid-resistant, field-strain (Jersey City) bed bugs compared with a control (water [99% hatch rate]), Bedlam (MGK-264, sumithrin [84% hatch rate]), Demand CS (lambda-cyhalothrin [91% hatch rate]), and Phantom SC (chlorfenapyr [95% hatch rate]). Demand CS and Temprid SC were most effective at preventing egg hatch (0%) for an insecticide-susceptible (Harold Harlan) strain, followed by Bedlam (28%). Phantom SC produced a hatch rate similar to the control (97% and 96%, respectively). Harold Harlan-strain nymphs showed 100% survival for the control but 0% survival for Bedlam and Phantom SC. Jersey City-strain nymphs showed 100% survival for the control, 99% survival for Bedlam, 0% survival for Demand CS, 4% survival for Phantom SC, and 38% survival for Temprid SC. Demand CS was less effective at preventing hatch (91% hatch rate) of Jersey City-strain nymphs but was the only product to kill all nymphs (0% survival). One of the least effective products for preventing Jersey City-strain egg hatch (Phantom SC, 95% hatch rate) was the second most effective at killing nymphs, leaving only six of 141 alive. These findings indicate that survival of directly sprayed eggs and residually exposed, first-instar nymphs varies by strain, life stage, and product used. © The Authors 2016. Published by Oxford University Press on behalf of Entomological
Survival Rates of Juvenile Salmonids Passing Through the Bonneville Dam and Spillway in 2008
Energy Technology Data Exchange (ETDEWEB)
Ploskey, Gene R.; Weiland, Mark A.; Faber, Derrek M.; Deng, Zhiqun; Johnson, Gary E.; Hughes, James S.; Zimmerman, Shon A.; Monter, Tyrell J.; Cushing, Aaron W.; Wilberding, Matthew C.; Durham, Robin E.; Townsend, R. L.; Skalski, J. R.; Buchanan, Rebecca A.; Kim, Jina; Fischer, Eric S.; Meyer, Matthew M.; McComas, Roy L.; Everett, Jason
2009-12-28
This report describes a 2008 acoustic telemetry survival study conducted by the Pacific Northwest National Laboratory for the Portland District of the U.S. Army Corps of Engineers. The study estimated the survival of juvenile Chinook salmon and steelhead passing Bonneville Dam (BON) and its spillway. Of particular interest was the relative survival of smolts detected passing through end spill bays 1-3 and 16-18, which had deep flow deflectors immediately downstream of spill gates, versus survival of smolts passing middle spill bays 4-15, which had shallow flow deflectors.
International Nuclear Information System (INIS)
Matijevic, M.; Grgic, D.; Jecmenica, R.
2016-01-01
This paper presents comparison of the Krsko Power Plant simplified Spent Fuel Pool (SFP) dose rates using different computational shielding methodologies. The analysis was performed to estimate limiting gamma dose rates on wall mounted level instrumentation in case of significant loss of cooling water. The SFP was represented with simple homogenized cylinders (point kernel and Monte Carlo (MC)) or cuboids (MC) using uranium, iron, water, and dry-air as bulk region materials. The pool is divided on the old and new section where the old one has three additional subsections representing fuel assemblies (FAs) with different burnup/cooling time (60 days, 1 year and 5 years). The new section represents the FAs with the cooling time of 10 years. The time dependent fuel assembly isotopic composition was calculated using ORIGEN2 code applied to the depletion of one of the fuel assemblies present in the pool (AC-29). The source used in Microshield calculation is based on imported isotopic activities. The time dependent photon spectra with total source intensity from Microshield multigroup point kernel calculations was then prepared for two hybrid deterministic-stochastic sequences. One is based on SCALE/MAVRIC (Monaco and Denovo) methodology and another uses Monte Carlo code MCNP6.1.1b and ADVANTG3.0.1. code. Even though this model is a fairly simple one, the layers of shielding materials are thick enough to pose a significant shielding problem for MC method without the use of effective variance reduction (VR) technique. For that purpose the ADVANTG code was used to generate VR parameters (SB cards in SDEF and WWINP file) for MCNP fixed-source calculation using continuous energy transport. ADVATNG employs a deterministic forward-adjoint transport solver Denovo which implements CADIS/FW-CADIS methodology. Denovo implements a structured, Cartesian-grid SN solver based on the Koch-Baker-Alcouffe parallel transport sweep algorithm across x-y domain blocks. This was first
Resolving an ostensible inconsistency in calculating the evaporation rate of sessile drops.
Chini, S F; Amirfazli, A
2017-05-01
This paper resolves an ostensible inconsistency in the literature in calculating the evaporation rate for sessile drops in a quiescent environment. The earlier models in the literature have shown that adapting the evaporation flux model for a suspended spherical drop to calculate the evaporation rate of a sessile drop needs a correction factor; the correction factor was shown to be a function of the drop contact angle, i.e. f(θ). However, there seemed to be a problem as none of the earlier models explicitly or implicitly mentioned the evaporation flux variations along the surface of a sessile drop. The more recent evaporation models include this variation using an electrostatic analogy, i.e. the Laplace equation (steady-state continuity) in a domain with a known boundary condition value, or known as the Dirichlet problem for Laplace's equation. The challenge is that the calculated evaporation rates using the earlier models seemed to differ from that of the recent models (note both types of models were validated in the literature by experiments). We have reinvestigated the recent models and found that the mathematical simplifications in solving the Dirichlet problem in toroidal coordinates have created the inconsistency. We also proposed a closed form approximation for f(θ) which is valid in a wide range, i.e. 8°≤θ≤131°. Using the proposed model in this study, theoretically, it was shown that the evaporation rate in the CWA (constant wetted area) mode is faster than the evaporation rate in the CCA (constant contact angle) mode for a sessile drop. Copyright © 2016 Elsevier B.V. All rights reserved.
Bayesian Analysis for Dynamic Generalized Linear Latent Model with Application to Tree Survival Rate
Directory of Open Access Journals (Sweden)
Yu-sheng Cheng
2014-01-01
Full Text Available Logistic regression model is the most popular regression technique, available for modeling categorical data especially for dichotomous variables. Classic logistic regression model is typically used to interpret relationship between response variables and explanatory variables. However, in real applications, most data sets are collected in follow-up, which leads to the temporal correlation among the data. In order to characterize the different variables correlations, a new method about the latent variables is introduced in this study. At the same time, the latent variables about AR (1 model are used to depict time dependence. In the framework of Bayesian analysis, parameters estimates and statistical inferences are carried out via Gibbs sampler with Metropolis-Hastings (MH algorithm. Model comparison, based on the Bayes factor, and forecasting/smoothing of the survival rate of the tree are established. A simulation study is conducted to assess the performance of the proposed method and a pika data set is analyzed to illustrate the real application. Since Bayes factor approaches vary significantly, efficiency tests have been performed in order to decide which solution provides a better tool for the analysis of real relational data sets.
Aksoy, Alper; Gungor, Melike; Sir, Emin
2017-01-01
The purpose of this study was to compare the results of fingertip replantations without (artery anastomosis only replantations) and with venous anastomosis (replantations in which both arterial and palmar venous anastomoses were performed). Also, distribution of the veins used for anastomosis was analyzed retrospectively. First 53 digits (47 patients) received only arterial anastomosis (group 1). For relieving venous congestion, external bleeding method was used. Last 41 digits (38 patients) received both arterial and palmar venous anastomoses without external bleeding (group 2). There was statistical significance of the survival rate between group 1 [77.3% (41/53)] and group 2 [92.6% (38/41)] (P = 0.039). Venous congestion was encountered at 10 digits in group 1 (all underwent necrosis totally) and at 3 digits in group 2 (both were moderate and could be salvaged partially) (P = 0.094, no statistical significance). There was statistical significance of the mean operation time for single-fingertip replantation between group 1 (80 ± 7.8 minutes) and group 2 (105 ± 14.5 minutes) (P replantations with palmar venous anastomosis have simpler postoperative care and lower drawbacks as compared with artery anastomosis-only replantations.
The combined effect of individual and neighborhood socioeconomic status on cancer survival rates.
Directory of Open Access Journals (Sweden)
Chun-Ming Chang
Full Text Available BACKGROUND: This population-based study investigated the relationship between individual and neighborhood socioeconomic status (SES and mortality rates for major cancers in Taiwan. METHODS: A population-based follow-up study was conducted with 20,488 cancer patients diagnosed in 2002. Each patient was traced to death or for 5 years. The individual income-related insurance payment amount was used as a proxy measure of individual SES for patients. Neighborhood SES was defined by income, and neighborhoods were grouped as living in advantaged or disadvantaged areas. The Cox proportional hazards model was used to compare the death-free survival rates between the different SES groups after adjusting for possible confounding and risk factors. RESULTS: After adjusting for patient characteristics (age, gender, Charlson Comorbidity Index Score, urbanization, and area of residence, tumor extent, treatment modalities (operation and adjuvant therapy, and hospital characteristics (ownership and teaching level, colorectal cancer, and head and neck cancer patients under 65 years old with low individual SES in disadvantaged neighborhoods conferred a 1.5 to 2-fold higher risk of mortality, compared with patients with high individual SES in advantaged neighborhoods. A cross-level interaction effect was found in lung cancer and breast cancer. Lung cancer and breast cancer patients less than 65 years old with low SES in advantaged neighborhoods carried the highest risk of mortality. Prostate cancer patients aged 65 and above with low SES in disadvantaged neighborhoods incurred the highest risk of mortality. There was no association between SES and mortality for cervical cancer and pancreatic cancer. CONCLUSIONS: Our findings indicate that cancer patients with low individual SES have the highest risk of mortality even under a universal health-care system. Public health strategies and welfare policies must continue to focus on this vulnerable group.
Energy Technology Data Exchange (ETDEWEB)
Nordenfors, C
1999-02-01
To determine dose rate in a gamma radiation field, based on measurements with a semiconductor detector, it is necessary to know how the detector effects the field. This work aims to describe this effect with Monte Carlo simulations and calculations, that is to identify the detector response function. This is done for a germanium gamma detector. The detector is normally used in the in-situ measurements that is carried out regularly at the department. After the response function is determined it is used to reconstruct a spectrum from an in-situ measurement, a so called unfolding. This is done to be able to calculate fluence rate and dose rate directly from a measured (and unfolded) spectrum. The Monte Carlo code used in this work is EGS4 developed mainly at Stanford Linear Accelerator Center. It is a widely used code package to simulate particle transport. The results of this work indicates that the method could be used as-is since the accuracy of this method compares to other methods already in use to measure dose rate. Bearing in mind that this method provides the nuclide specific dose it is useful, in radiation protection, since knowing what the relations between different nuclides are and how they change is very important when estimating the risks
Calculating in situ degradation rates of hydrocarbon compounds in deep waters of the Gulf of Mexico.
Thessen, Anne E; North, Elizabeth W
2017-09-15
Biodegradation is an important process for hydrocarbon weathering that influences its fate and transport, yet little is known about in situ biodegradation rates of specific hydrocarbon compounds in the deep ocean. Using data collected in the Gulf of Mexico below 700m during and after the Deepwater Horizon oil spill, we calculated first-order degradation rate constants for 49 hydrocarbons and inferred degradation rate constants for an additional 5 data-deficient hydrocarbons. Resulting calculated (not inferred) half-lives of the hydrocarbons ranged from 0.4 to 36.5days. The fastest degrading hydrocarbons were toluene (k=-1.716), methylcyclohexane (k=-1.538), benzene (k=-1.333), and C1-naphthalene (k=-1.305). The slowest degrading hydrocarbons were the large straight-chain alkanes, C-26 through C-33 (k=-0.0494 through k=-0.007). Ratios of C-18 to phytane supported the hypothesis that the primary means of degradation in the subsurface was microbial biodegradation. These degradation rate constants can be used to improve models describing the fate and transport of hydrocarbons in the event of an accidental deep ocean oil spill. Copyright © 2017 Elsevier Ltd. All rights reserved.
Error rate of automated calculation for wound surface area using a digital photography.
Yang, S; Park, J; Lee, H; Lee, J B; Lee, B U; Oh, B H
2018-02-01
Although measuring would size using digital photography is a quick and simple method to evaluate the skin wound, the possible compatibility of it has not been fully validated. To investigate the error rate of our newly developed wound surface area calculation using digital photography. Using a smartphone and a digital single lens reflex (DSLR) camera, four photographs of various sized wounds (diameter: 0.5-3.5 cm) were taken from the facial skin model in company with color patches. The quantitative values of wound areas were automatically calculated. The relative error (RE) of this method with regard to wound sizes and types of camera was analyzed. RE of individual calculated area was from 0.0329% (DSLR, diameter 1.0 cm) to 23.7166% (smartphone, diameter 2.0 cm). In spite of the correction of lens curvature, smartphone has significantly higher error rate than DSLR camera (3.9431±2.9772 vs 8.1303±4.8236). However, in cases of wound diameter below than 3 cm, REs of average values of four photographs were below than 5%. In addition, there was no difference in the average value of wound area taken by smartphone and DSLR camera in those cases. For the follow-up of small skin defect (diameter: <3 cm), our newly developed automated wound area calculation method is able to be applied to the plenty of photographs, and the average values of them are a relatively useful index of wound healing with acceptable error rate. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
A comparative study of different methods for calculating electronic transition rates
Kananenka, Alexei A.; Sun, Xiang; Schubert, Alexander; Dunietz, Barry D.; Geva, Eitan
2018-03-01
We present a comprehensive comparison of the following mixed quantum-classical methods for calculating electronic transition rates: (1) nonequilibrium Fermi's golden rule, (2) mixed quantum-classical Liouville method, (3) mean-field (Ehrenfest) mixed quantum-classical method, and (4) fewest switches surface-hopping method (in diabatic and adiabatic representations). The comparison is performed on the Garg-Onuchic-Ambegaokar benchmark charge-transfer model, over a broad range of temperatures and electronic coupling strengths, with different nonequilibrium initial states, in the normal and inverted regimes. Under weak to moderate electronic coupling, the nonequilibrium Fermi's golden rule rates are found to be in good agreement with the rates obtained via the mixed quantum-classical Liouville method that coincides with the fully quantum-mechanically exact results for the model system under study. Our results suggest that the nonequilibrium Fermi's golden rule can serve as an inexpensive yet accurate alternative to Ehrenfest and the fewest switches surface-hopping methods.
Small groups, large profits: Calculating interest rates in community-managed microfinance
DEFF Research Database (Denmark)
Rasmussen, Ole Dahl
2012-01-01
Savings groups are a widely used strategy for women’s economic resilience – over 80% of members worldwide are women, and in the case described here, 72.5%. In these savings groups it is common to see the interest rate on savings reported as "20-30% annually". Using panel data from 204 groups...... in Malawi, I show that the right figure is likely to be at least twice this figure. For these groups, the annual return is 62%. The difference comes from sector-wide application of a non-standard interest rate calculations and unrealistic assumptions about the savings profile in the groups. As a result......, it is impossible to compare returns in savings groups with returns elsewhere. Moreover, the interest on savings is incomparable to the interest rate on loans. I argue for the use of a standardized comparable metric and suggest easy ways to implement it. Developments of new tools and standard along these lines...
Short-term survival and mortality rates in a retrospective study of colic in 1588 Danish horses
DEFF Research Database (Denmark)
Christophersen, Mogens Teken; Dupont, Nana Hee; Berg-Sørensen, Kristina S.
2014-01-01
Background: Outcomes of colic treatment are of great interest to clinicians, horse owners and insurers. One commonly used criterion of success is the overall short-term survival rate. This is used as to compare treatments and to measure quality of veterinary care, but may be biased by demographic...... the countries, which may bias the outcomes. This study indicates that qualitative interview studies on owners ’ attitudes towards animal suffering and euthanasia need to be conducted. Our opinion is that survival rates are not valid as sole indicators of quality of care in colic treatment due to selection bias...
Radiological dose rate calculations for the International Thermonuclear Experimental Reactor (ITER)
International Nuclear Information System (INIS)
Khater, H.Y.; Santoro, R.T.
1996-01-01
Two-dimensional biological dose rates were calculated at different locations outside the International Thermonuclear Experimental Reactor (ITER) design. An 18 degree sector of the reactor was modeled in r-θ geometry. The calculations were performed for three different pulsing scenarios. This included a single pulse of 1000 s duration, 10 pulses of 1000 s duration with a 50% duty factor, and 9470 pulses of 1000 s duration with a 50% duty factor for a total fluence of 0.3 MW.a/m 2 . The dose rates were calculated as a function of toroidal angle at locations in the space between the toroidal field (TF) coils and cryostat, and in the space between the cryostat and the biological shield. The two-dimensional results clearly showed the toroidal effect, which is dominated by contribution from the activation of the cryostat and the biological shield. After one pulse, full access to the machine is possible within a few hours following shutdown. After 10 pulses, full access is also possible within the first day following shutdown. At the end of the Basic Performance Phase (BPP), full access is possible at any of the locations considered after one week following shutdown. 5 refs., 5 figs., 2 tabs
Experimental validation of calculated capture rate for nucleus involved in fuel cycle
International Nuclear Information System (INIS)
Benslimane-Bouland, A.
1997-01-01
This work has been realized in the framework of the estimation of actinides and fission products nuclear data for the today and future reactors. The first part presents the existing integral experiments for the calculated capture rate and the methods used in the design of reactor cores calculation formulary. The second part is devoted to the interpretation of three specific irradiation experiments which allow the evaluation of the today knowledge on studied data and their associated uncertainties. The last part presents a synthesis of results and the statistical methods used for the adjustment of data bases. This work shows that, in spite of the reactors Physics progresses on the knowledge of uranium and plutonium capture cross sections, uncertainties remain for minor actinides. (A.L.B.)
Directory of Open Access Journals (Sweden)
John G Blake
Full Text Available Knowledge of survival rates of Neotropical landbirds remains limited, with estimates of apparent survival available from relatively few sites and species. Previously, capture-mark-recapture models were used to estimate apparent survival of 31 species (30 passerines, 1 Trochilidae from eastern Ecuador based on data collected from 2001 to 2006. Here, estimates are updated with data from 2001-2012 to determine how additional years of data affect estimates; estimates for six additional species are provided. Models assuming constant survival had highest support for 19 of 31 species when based on 12 years of data compared to 27 when based on six; models incorporating effects of transients had the highest support for 12 of 31 species compared to four when based on 12 and six years, respectively. Average apparent survival based on the most highly-supported model (based on model averaging, when appropriate was 0.59 (± 0.02 SE across 30 species of passerines when based on 12 years and 0.57 (± 0.02 when based on six. Standard errors of survival estimates based on 12 years were approximately half those based on six years. Of 31 species in both data sets, estimates of apparent survival were somewhat lower for 13, somewhat higher for 17, and remained unchanged for one; confidence intervals for estimates based on six and 12 years of data overlapped for all species. Results indicate that estimates of apparent survival are comparable but more precise when based on longer-term data sets; standard error of the estimates was negatively correlated with numbers of captures (rs = -0.72 and recaptures (rs = -0.93, P<0.001 in both cases. Thus, reasonable estimates of apparent survival may be obtained with relatively few years of data if sample sizes are sufficient.
Simpson, Matthew J; Baker, Ruth E
2015-09-07
Unlike standard applications of transport theory, the transport of molecules and cells during embryonic development often takes place within growing multidimensional tissues. In this work, we consider a model of diffusion on uniformly growing lines, disks, and spheres. An exact solution of the partial differential equation governing the diffusion of a population of individuals on the growing domain is derived. Using this solution, we study the survival probability, S(t). For the standard non-growing case with an absorbing boundary, we observe that S(t) decays to zero in the long time limit. In contrast, when the domain grows linearly or exponentially with time, we show that S(t) decays to a constant, positive value, indicating that a proportion of the diffusing substance remains on the growing domain indefinitely. Comparing S(t) for diffusion on lines, disks, and spheres indicates that there are minimal differences in S(t) in the limit of zero growth and minimal differences in S(t) in the limit of fast growth. In contrast, for intermediate growth rates, we observe modest differences in S(t) between different geometries. These differences can be quantified by evaluating the exact expressions derived and presented here.
Benchmarking of MCNP for calculating dose rates at an interim storage facility for nuclear waste.
Heuel-Fabianek, Burkhard; Hille, Ralf
2005-01-01
During the operation of research facilities at Research Centre Jülich, Germany, nuclear waste is stored in drums and other vessels in an interim storage building on-site, which has a concrete shielding at the side walls. Owing to the lack of a well-defined source, measured gamma spectra were unfolded to determine the photon flux on the surface of the containers. The dose rate simulation, including the effects of skyshine, using the Monte Carlo transport code MCNP is compared with the measured dosimetric data at some locations in the vicinity of the interim storage building. The MCNP data for direct radiation confirm the data calculated using a point-kernel method. However, a comparison of the modelled dose rates for direct radiation and skyshine with the measured data demonstrate the need for a more precise definition of the source. Both the measured and the modelled dose rates verified the fact that the legal limits (<1 mSv a(-1)) are met in the area outside the perimeter fence of the storage building to which members of the public have access. Using container surface data (gamma spectra) to define the source may be a useful tool for practical calculations and additionally for benchmarking of computer codes if the discussed critical aspects with respect to the source can be addressed adequately.
Quantum chemical and conventional TST calculations of rate constants for the OH + alkane reaction
International Nuclear Information System (INIS)
Bravo-Perez, Graciela; Alvarez-Idaboy, J. Raul; Jimenez, Annia Galano; Cruz-Torres, Armando
2005-01-01
Reactions of OH with methane, ethane, propane, i-butane, and n-butane have been modeled using ab initio (MP2) and hybrid DFT (BHandHLYP) methods, and the 6-311G(d,p) basis set. Furthermore, single-point calculations at the CCSD(T) level were carried out at the optimized geometries. The rate constants have been calculated using the conventional transition-state theory (CTST). Arrhenius equations are proposed in the temperature range of 250-650 K. Hindered Internal Rotation partition functions calculations were explicitly carried out and included in the total partition functions. These corrections showed to be relevant in the determination of the pre-exponential parameters, although not so important as in the NO 3 + alkane reactions [G. Bravo-Perez, J.R. Alvarez-Idaboy, A. Cruz-Torres, M.E. Ruiz, J. Phys. Chem. A 106 (2002) 4645]. The explicit participation of the tunnel effect has been taken into account. The calculated rate coefficients provide a very good agreement with the experimental data. The best agreement for the overall alkane + OH reactions seemed to occur when the BHandHLYP geometries and partition functions are used. For propane and i-butane, in addition to the respective secondary and tertiary H-abstraction channels, the primary one has been considered. These pathways are confirmed to be significant in spite of the large differences in activation energies between primary and secondary or primary and tertiary channels, respectively of propane and i-butane reactions and should not be disregarded
Directory of Open Access Journals (Sweden)
Miguel Mies
2012-06-01
Full Text Available Tridacnid clams are conspicuous inhabitants of Indo-Pacific coral reefs and are traded and cultivated for the aquarium and food industries. In the present study, daily growth rates of larvae of the giant clam Tridacna crocea were determined in the laboratory during the first week of life. Adults were induced to spawn via intra-gonadal serotonin injection through the byssal orifice. After spawning oocytes were collected, fertilized and kept in 3 L glass beakers and raceways treated with antibiotics to avoid culture contamination. Larvae were fed twice with the microalga Isochrysis galbana and zooxanthellae were also offered twice during the veliger stage (days 4 and 6. Larval length was measured using a digitizing tablet coupled to a microcomputer. Larval mortality was exponential during the first 48 hours of life declining significantly afterwards. Mean growth rate was 11.3 μm day-1, increasing after addition of symbionts to 18.0 μm day-1. Survival increased to ca. 75% after the addition of zooxanthellae. The results describe the growth curve for T. crocea larvae and suggest that the acquisition of symbionts by larvae may be useful for larval growth and survival even before larvae have attained metamorphosis.Bivalves tridacnídeos são habitantes conspícuos dos recifes da região do Indo-Pacífico e são cultivados e comercializados para os mercados alimentício e aquarista. No estudo apresentado foram determinadas as taxas de crescimento diário durante a primeira semana de vida da larva do bivalve ornamental Tridacna crocea. As matrizes foram induzidas à desova por meio de uma injeção intragonadal de serotonina realizada através do orifício bissal. Após desova, ovócitos foram coletados, fertilizados e mantidos em béqueres de vidro e tanques de fluxo contínuo tratados com antibióticos para evitar contaminação. Larvas foram alimentadas em duas ocasiões com a microalga Isochrysis galbana e zooxantelas foram oferecidas também por
Calculation of the effective environmental dose rate for ESR and luminescence dating
International Nuclear Information System (INIS)
Brennan, B.J.
2001-01-01
The determination of the age of a sample using luminescence and ESR dating techniques requires knowledge of the sample's average effective environmental dose rate due to natural radiation sources (alpha, beta, gamma, and cosmic), and age estimates can never be more accurate than the estimate of this dose rate. The estimation process is often complicated by spatial and temporal inhomogeneities in the distribution of natural radiation sources. This paper discusses applications of radiation physics in modelling the effects of these inhomogeneities to ensure accurate estimation of the average dose rate for the sample. For natural alpha, beta, and gamma sources, 'dose point kernels' are employed in calculations using an assumed model for the spatial and temporal dependence of source concentrations. These three types of radiation have rather different penetration properties, with their typical effective ranges being multiples of 10 micrometre, 1 mm, and 100 mm respectively. For each type of radiation, applications are discussed where spatial inhomogeneity in the distribution of sources around and in a sample has a serious effect on the average dose rate to the sample. In some cases, (e.g. gamma dose estimation in 'lumpy' environments) lack of detailed knowledge precludes accurate modelling of the site for a particular sample, but useful statistical information can still be obtained. Temporal variation of radioactive source concentrations is usually coupled with spatial effects and can arise from processes such as parent-daughter disequilibrium, uptake or leaching of sources, or variation in burial depth or water saturation. Again, calculations based non a known or assumed history can be employed to obtain a time-averaged dose rate for a sample. The accuracy with which these calculations can reflect the true environmental dose rate is limited principally by the reliability of the model assumed, which in turn depends on the state of knowledge of the site and its history
Calculating the dim light melatonin onset: the impact of threshold and sampling rate.
Molina, Thomas A; Burgess, Helen J
2011-10-01
The dim light melatonin onset (DLMO) is the most reliable circadian phase marker in humans, but the cost of assaying samples is relatively high. Therefore, the authors examined differences between DLMOs calculated from hourly versus half-hourly sampling and differences between DLMOs calculated with two recommended thresholds (a fixed threshold of 3 pg/mL and a variable "3k" threshold equal to the mean plus two standard deviations of the first three low daytime points). The authors calculated these DLMOs from salivary dim light melatonin profiles collected from 122 individuals (64 women) at baseline. DLMOs derived from hourly sampling occurred on average only 6-8 min earlier than the DLMOs derived from half-hourly saliva sampling, and they were highly correlated with each other (r ≥ 0.89, p 30 min from the DLMO derived from half-hourly sampling. The 3 pg/mL threshold produced significantly less variable DLMOs than the 3k threshold. However, the 3k threshold was significantly lower than the 3 pg/mL threshold (p < .001). The DLMOs calculated with the 3k method were significantly earlier (by 22-24 min) than the DLMOs calculated with the 3 pg/mL threshold, regardless of sampling rate. These results suggest that in large research studies and clinical settings, the more affordable and practical option of hourly sampling is adequate for a reasonable estimate of circadian phase. Although the 3 pg/mL fixed threshold is less variable than the 3k threshold, it produces estimates of the DLMO that are further from the initial rise of melatonin.
Directory of Open Access Journals (Sweden)
A Roozbehi
2012-10-01
Full Text Available Background & Aim: The preserving embryos, the risk of multiple pregnancies, the existence of factors in stimulated uterine cycle, are important forces in perfecting embryo cryopreservation. The aim of current study was to assess Survival, Fertilization and Developmental Rates (SRs, FRs, DRs of the mouse oocytes and embryos using cryotop and low concentrated cryoprotectants solutions. Methods: Mouse C57BL/6 oocytes and embryos were collected. Oocytes SRs, FRs, DRs were recorded after cryotop-vitrification/ warming. As well as comparing fresh oocytes and embryos, the data obtained from experimental groups (exp. applying 1.25, 1.0, and 0.75 Molar (M CPAs were analyzed in comparison to those of exp. adopting 1.5 M CPAs (largely-used concentration of EthylenGlycol (EG and Dimethylsulphoxide (DMSO. Results: The data of oocytes exposed to 1.25 M CPAs were in consistency with those exposed to 1.5 M and control group in terms of SR, FR and DR. As fewer concentrations were applied, the more decreased SRs, FRs and DRs were obtained from other experimental groups. The results of embryos were exposed to 1.25 M and 1.0 M was close to those vitrified with 1.5 M and fresh embryos. The results of 0.75 M concentrated CPAs solutions were significantly lower than those of control, 1.5 M and 1.0 M treated groups. Conclusion: CPAs limited reduction to 1.25 M and 1.0 M instead of using 1.5 M, for oocyte and embryo cryotop-vitrification procedure may be a slight adjustment.
Verification of the calculation program for brachytherapy planning system of high dose rate (PLATO)
International Nuclear Information System (INIS)
Almansa, J.; Alaman, C.; Perez-Alija, J.; Herrero, C.; Real, R. del; Ososrio, J. L.
2011-01-01
In our treatments are performed brachytherapy high dose rate since 2007. The procedures performed include gynecological intracavitary treatment and interstitial. The treatments are performed with a source of Ir-192 activity between 5 and 10 Ci such that small variations in treatment times can cause damage to the patient. In addition the Royal Decree 1566/1998 on Quality Criteria in radiotherapy establishes the need to verify the monitor units or treatment time in radiotherapy and brachytherapy. All this justifies the existence of a redundant system for brachytherapy dose calculation that can reveal any abnormality is present.
Comparison of calculated and measured soil-gas radon concentration and radon exhalation rate
International Nuclear Information System (INIS)
Neznal, Martin; Neznal, Matej; Jiranek, Martin
2000-01-01
The computer model RADON2D for WINDOWS, which makes it possible to estimate the radon exhalation rate from the ground surface and the distribution of soil-gas radon concentration, was tested using a large set of experimental data coming from four reference areas located in regions with different geological structure. A good agreement between calculated and experimental data was observed. In the majority of cases, a correct description of the real situation was obtained using non-modified experimental input data. (author)
Preliminary Calculations of Shutdown Dose Rate for the CTS Diagnostics System
DEFF Research Database (Denmark)
Klinkby, Esben Bryndt; Nonbøl, Erik; Lauritzen, Bent
2015-01-01
DTU and IST 2 are partners in the design of a collective Thomson Scattering (CTS) diagnostics for ITER through a contract with F4E. The CTS diagnostic utilizes probing radiation of ~60 GHz emitted into the plasma and, using a mirror, collects the scattered radiation by an array of receivers. Having...... on supplying input which affect the system design. Examples include: - Heatloads on plasma facing mirrors and preliminary stress and thermal analysis - Port plug cooling requirements and it's dependence on system design (in particular blanket cut-out) - Shutdown dose-rate calculations (relative analysis...
Approximate techniques for calculating gamma ray dose rates in nuclear power plants
International Nuclear Information System (INIS)
Lahti, G.P.
1986-01-01
Although today's computers have made three-dimensional discrete ordinates transport codes a virtual reality, there is still a need for approximate techniques for estimating radiation environments. This paper discusses techniques for calculating gamma ray dose rates in nuclear power plants where Compton scattering is the dominant attenuation mechanism. The buildup factor method is reviewed; its use and misuse are discussed. Several useful rules-of-thumb are developed. The paper emphasizes the need for understanding the fundamental physics and draws heavily on the old, classic references
Accurate Bit Error Rate Calculation for Asynchronous Chaos-Based DS-CDMA over Multipath Channel
Kaddoum, Georges; Roviras, Daniel; Chargé, Pascal; Fournier-Prunaret, Daniele
2009-12-01
An accurate approach to compute the bit error rate expression for multiuser chaosbased DS-CDMA system is presented in this paper. For more realistic communication system a slow fading multipath channel is considered. A simple RAKE receiver structure is considered. Based on the bit energy distribution, this approach compared to others computation methods existing in literature gives accurate results with low computation charge. Perfect estimation of the channel coefficients with the associated delays and chaos synchronization is assumed. The bit error rate is derived in terms of the bit energy distribution, the number of paths, the noise variance, and the number of users. Results are illustrated by theoretical calculations and numerical simulations which point out the accuracy of our approach.
Calculation of Rates of 4p–4d Transitions in Ar II
Directory of Open Access Journals (Sweden)
Alan Hibbert
2017-02-01
Full Text Available Recent experimental work by Belmonte et al. (2014 has given rates for some 4p–4d transitions that are significantly at variance with the previous experimental work of Rudko and Tang (1967 recommended in the NIST tabulations. To date, there are no theoretical rates with which to compare. In this work, we provide such theoretical data. We have undertaken a substantial and systematic configuration interaction calculation, with an extrapolation process applied to ab initio mixing coefficients, which gives energy differences in agreement with experiment. The length and velocity forms give values that are within 10%–15% of each other. Our results are in sufficiently close agreement with those of Belmonte et al. that we can confidently recommend that their results are much more accurate than the early results of Rudko and Tang, and should be adopted in place of the latter.
Effects of non-implantation factors on survival rate of microbe irradiated by low-energy N+
International Nuclear Information System (INIS)
Yang Tianyou; Chen Linhai; Qin Guangyong; Li Zongwei; Su Mingjie; Wang Yanping; Chang Shenghe; Huo Yuping; Li Zongyi
2006-01-01
The effects of non-implantation factors, such as drying, vacuum and the staying time of the E.coli LE392 culture, on survival rate of E.coli LE392 were studied when E.coli LE392 was irradiated by the low-energy N + . The results show that the survival rate of E.coli LE392 does not reduce steadily all the time but rapidly drops sometime during drying. The survival rate of E.coli LE392 declines sharply as the samples are placed in vacuum, then falls in distinctively with increasing of time. the tolerance of E.coli LE392 towards vacuum increasingly strengthens when the E.coli LE392 culture is placed at room temperature. Preparing the culture in batchs can ensure the consistency of the irradiated samples and avoid errors caused by the inconsistent samples. When the non-implantation factors are controlled, E.coli is implanted by 30 kev N + of 1 x 10 14 cm -2 and 3 x 10 15 cm -2 , respectively. And the results show no difference in the E.coli's survival rates between batchs at the same dose. (authors)
International Nuclear Information System (INIS)
Wang Shuyang; Li Jinghua; Jiang Boling
2014-01-01
In this study, three kinds of alfalfa including Zhonglan 1, BC-04-477 and Ta Cheng were treated with different doses of "1"2C"6"+ (75 keV) heavy ion radiation, and then the influence of survival rate, catalase (CAT) and peroxidase (POD) activity of M1 with low temperature stress were tested. The results showed that under the condition of 400 Gy radiation dose, the survival rate and CAT activity of Zhonglan 1 under low temperature stress have increased by 33.3%, 56.3% respectively compared with those of the control group, while there was no difference in POD activity between those two groups. The survival rate, CAT and POD activity of BC-04-477 treated with low temperature have been improved by 33.3%, 69.2%, 5.1% respectively compared with those of the control group when the radiation dose was 400 Gy. Compared with those of the control group, the survival rate, CAT and POD activity of Ta Cheng under low temperature stress have been improved by 25%, 26%,22.8% respectively when the radiation dose was 800 Gy. These results indicate that the viability and the cold resistance ability of Zhong Lan 1, BC-04-477 and Ta Cheng can be improved by "1"2C"6"+ radiation. (authors)
Influence of the cavity-size on the survival rate of proximal ART restorations in primary molars
Kemoli, A.M.; van Amerongen, W.E.
2009-01-01
Aim. To evaluate the influence of the size of proximal cavities on the survival rate of the atraumatic restorative treatment (ART) restorations. Design. A total of 804 children, aged 6-8 years, from a low socio-economic community, with an ART restorable proximal carious lesion in their primary
Directory of Open Access Journals (Sweden)
Hao-Sheng Chang
2015-03-01
Conclusion: The overall survival rate of dental implants with overdenture rehabilitation was 95.3% (91.3% in maxillae vs. 96.4% in mandibles within the past 20 years. With careful treatment planning, implant-supported overdenture is an interesting treatment alternative with better esthetic, retention, stability, and good hygienic maintenance for patients with severe ridge resorption.
Magma addition rates in continental arcs: New methods of calculation and global implications
Ratschbacher, B. C.; Paterson, S. R.
2017-12-01
The transport of mass, heat and geochemical constituents (elements and volatiles) from the mantle to the atmosphere occurs via magma addition to the lithosphere. Calculation of magma addition rates (MARs) in continental arcs based on exposed proportions of igneous arc rocks is complex and rarely consistently determined. Multiple factors influence MAR calculations such as crust versus mantle contributions to magmas, a change in MARs across the arc and with depths throughout the arc crustal column, `arc tempos' with periods of high and low magmatic activity, the loss of previous emplaced arc rocks by subsequent magmatism and return to the mantle, arc migration, variations in the intrusive versus extrusive additions and evolving arc widths and thicknesses during tectonism. All of these factors need to be considered when calculating MARs.This study makes a new attempt to calculate MARs in continental arcs by studying three arc sections: the Famatinian arc, Argentina, the Sierra Nevada batholith, California and the Coast Mountain batholith, Washington and British Columbia. Arcs are divided into fore-arc, main arc and back arc sections and `boxes' with a defined width, length and thickness spanning upper middle and lower crustal levels are assigned to each section. Representative exposed crustal slices for each depth are then used to calculate MARs based on outcrop proportions for each box. Geochemical data is used to infer crustal recycling percentages and total thickness of the arc. Preliminary results show a correlation between MARs, crustal thicknesses and magmatic flare-up durations. For instance, the Famatinian arc shows a strong decrease in MARs between the main arc section (9.4 km3/Ma/arc-km) and the fore-arc (0.61 km3/Ma/arc-km) and back-arc (1.52 km3/Ma/arc-km) regions and an increase in the amount of magmatism with depth.Global MARs over geologic timescales have the potential to investigate mantle melt generation rates and the volatile outgassing contribution
Direct calculation of ice homogeneous nucleation rate for a molecular model of water
Haji-Akbari, Amir; Debenedetti, Pablo G.
2015-01-01
Ice formation is ubiquitous in nature, with important consequences in a variety of environments, including biological cells, soil, aircraft, transportation infrastructure, and atmospheric clouds. However, its intrinsic kinetics and microscopic mechanism are difficult to discern with current experiments. Molecular simulations of ice nucleation are also challenging, and direct rate calculations have only been performed for coarse-grained models of water. For molecular models, only indirect estimates have been obtained, e.g., by assuming the validity of classical nucleation theory. We use a path sampling approach to perform, to our knowledge, the first direct rate calculation of homogeneous nucleation of ice in a molecular model of water. We use TIP4P/Ice, the most accurate among existing molecular models for studying ice polymorphs. By using a novel topological approach to distinguish different polymorphs, we are able to identify a freezing mechanism that involves a competition between cubic and hexagonal ice in the early stages of nucleation. In this competition, the cubic polymorph takes over because the addition of new topological structural motifs consistent with cubic ice leads to the formation of more compact crystallites. This is not true for topological hexagonal motifs, which give rise to elongated crystallites that are not able to grow. This leads to transition states that are rich in cubic ice, and not the thermodynamically stable hexagonal polymorph. This mechanism provides a molecular explanation for the earlier experimental and computational observations of the preference for cubic ice in the literature. PMID:26240318
Heart rate calculation from ensemble brain wave using wavelet and Teager-Kaiser energy operator.
Srinivasan, Jayaraman; Adithya, V
2015-01-01
Electroencephalogram (EEG) signal artifacts are caused by various factors, such as, Electro-oculogram (EOG), Electromyogram (EMG), Electrocardiogram (ECG), movement artifact and line interference. The relatively high electrical energy cardiac activity causes EEG artifacts. In EEG signal processing the general approach is to remove the ECG signal. In this paper, we introduce an automated method to extract the ECG signal from EEG using wavelet and Teager-Kaiser energy operator for R-peak enhancement and detection. From the detected R-peaks the heart rate (HR) is calculated for clinical diagnosis. To check the efficiency of our method, we compare the HR calculated from ECG signal recorded in synchronous with EEG. The proposed method yields a mean error of 1.4% for the heart rate and 1.7% for mean R-R interval. The result illustrates that, proposed method can be used for ECG extraction from single channel EEG and used in clinical diagnosis like estimation for stress analysis, fatigue, and sleep stages classification studies as a multi-model system. In addition, this method eliminates the dependence of additional synchronous ECG in extraction of ECG from EEG signal process.
Verification of the LWRARC code for light-water-reactor afterheat rate calculations
International Nuclear Information System (INIS)
Murphy, B.D.
1998-02-01
This report describes verification studies carried out on the LWRARC (Light-Water-Reactor Afterheat Rate Calculations) computer code. The LWRARC code is proposed for automating the implementation of procedures specified in Draft Revision 1 of the U.S. Nuclear Regulatory Commission (NRC) Regulatory Guide 3.54, open-quotes Spent-Fuel Heat Generation in an Independent Spent-Fuel Storage Installation,close quotes which gives guidelines on the calculation of decay heat for spent nuclear fuel. Draft Regulatory Guide 3.54 allows one to estimate decay-heat values by means of a table lookup procedure with interpolation performed between table-entry values. The tabulated values of the relevant parameters span ranges that are appropriate for spent fuel from a boiling-water reactor (BWR) or a pressurized-water reactor (PWR), as the case may be, and decay-heat rates are obtained for spent fuel whose properties are within those parameter limits. In some instances, where these limits are either exceeded or where they approach critical regions, adjustments are invoked following table lookup. The LWRARC computer code is intended to replicate the manual process just described. In the code, the table lookup is done by entering a database and carrying out interpolations. The code then determines if adjustments apply, and, if this is the case, adjustment factors are calculated separately. The manual procedures in the Draft Regulatory Guide have been validated (i.e., they produce results that are good estimates of reality). The work reported in this document verifies that the LWRARC code replicates the manual procedures of the Draft Regulatory Guide, and that the code, taken together with the Draft Regulatory Guide, can support both verification and validation processes
ESTIMATION OF FLEXIBILITY OF AN ORGANIZATION ON THE GROUND OF THE CALCULATION OF PROFIT MARGIN RATE
Directory of Open Access Journals (Sweden)
Olga Gennadevna Rybakova
2016-12-01
Full Text Available The article deals with the problem of the flexibility of an organization as the ability to adapt effectively to the external environment. The authors have identified and investigated different approaches to estimating the flexibility of an organization on the ground of flexibility grading, calculation of the general index of flexibility as well as the calculation of flexibility’s ranking score. We have identified the advantages and disadvantages of these approaches. A new method of the estimation of an organization’s flexibility on the ground of the calculation of relative profit margin has been developed. This method is the multifunctional assessment tool of enterprise’s functionability in the current context of difficult and volatile economic environment. It allows in the early stage to identify negative trends in the production and financial figures and thus, it enables the organizational leadership to take steps in advance in order to avert a crisis in its activity. Keeping the profit margin at the same rate at the forced contraction of output, because of the negative impact of external factors, will confirm that the organization has adapted to the external environment and, therefore, it is flexible. The organization can be considered with margin rate beginning to low up to zero value as an organization with an insufficient level of flexibility that is at the “zone of crisis” and it is characterized by the depletion of reserved funds and reduction of current assets. Loss-maker is nonflexible and the presence of loss means that the organization has an evident sign of crisis and it can be bankrupt.
A simple algebraic cancer equation: calculating how cancers may arise with normal mutation rates
Directory of Open Access Journals (Sweden)
Shibata Darryl
2010-01-01
Full Text Available Abstract Background The purpose of this article is to present a relatively easy to understand cancer model where transformation occurs when the first cell, among many at risk within a colon, accumulates a set of driver mutations. The analysis of this model yields a simple algebraic equation, which takes as inputs the number of stem cells, mutation and division rates, and the number of driver mutations, and makes predictions about cancer epidemiology. Methods The equation [p = 1 - (1 - (1 - (1 - udkNm ] calculates the probability of cancer (p and contains five parameters: the number of divisions (d, the number of stem cells (N × m, the number of critical rate-limiting pathway driver mutations (k, and the mutation rate (u. In this model progression to cancer "starts" at conception and mutations accumulate with cell division. Transformation occurs when a critical number of rate-limiting pathway mutations first accumulates within a single stem cell. Results When applied to several colorectal cancer data sets, parameter values consistent with crypt stem cell biology and normal mutation rates were able to match the increase in cancer with aging, and the mutation frequencies found in cancer genomes. The equation can help explain how cancer risks may vary with age, height, germline mutations, and aspirin use. APC mutations may shorten pathways to cancer by effectively increasing the numbers of stem cells at risk. Conclusions The equation illustrates that age-related increases in cancer frequencies may result from relatively normal division and mutation rates. Although this equation does not encompass all of the known complexity of cancer, it may be useful, especially in a teaching setting, to help illustrate relationships between small and large cancer features.
Zhao, Yu; Li, Yang; Mao, Shuangshuang; Sun, Wei; Yao, Rui
2015-11-02
Three-dimensional (3D) cell printing technology has provided a versatile methodology to fabricate cell-laden tissue-like constructs and in vitro tissue/pathological models for tissue engineering, drug testing and screening applications. However, it still remains a challenge to print bioinks with high viscoelasticity to achieve long-term stable structure and maintain high cell survival rate after printing at the same time. In this study, we systematically investigated the influence of 3D cell printing parameters, i.e. composition and concentration of bioink, holding temperature and holding time, on the printability and cell survival rate in microextrusion-based 3D cell printing technology. Rheological measurements were utilized to characterize the viscoelasticity of gelatin-based bioinks. Results demonstrated that the bioink viscoelasticity was increased when increasing the bioink concentration, increasing holding time and decreasing holding temperature below gelation temperature. The decline of cell survival rate after 3D cell printing process was observed when increasing the viscoelasticity of the gelatin-based bioinks. However, different process parameter combinations would result in the similar rheological characteristics and thus showed similar cell survival rate after 3D bioprinting process. On the other hand, bioink viscoelasticity should also reach a certain point to ensure good printability and shape fidelity. At last, we proposed a protocol for 3D bioprinting of temperature-sensitive gelatin-based hydrogel bioinks with both high cell survival rate and good printability. This research would be useful for biofabrication researchers to adjust the 3D bioprinting process parameters quickly and as a referable template for designing new bioinks.
Gibson, Thomas W G; Brisson, Brigitte A; Sears, William
2005-07-01
To determine the survival rates of dogs and cats that underwent surgical treatment for traumatic diaphragmatic hernia within 24 hours of admission and determine whether timing of surgery affected perioperative survival rate. Retrospective study. 63 dogs and 29 cats treated surgically for traumatic diaphragmatic hernia. Medical records were reviewed to evaluate associations between perioperative survival rates and variables including timing of surgery in relation to admission and acute versus chronic diaphragmatic hernia. Among the 92 animals, 82 (89.1%) were discharged alive after surgery. Sixty-four (69.6%) patients received surgical intervention within 12 hours of admission, and 84 (91.3%) received surgical intervention within 24 hours of admission. Median time from admission to discharge was 4 days (2 to 33 days). Data for acute cases (68 dogs and cats) were analyzed separately. Sixty-three (92.6%) patients with acute diaphragmatic hernia received surgical intervention within 24 hours of admission to the hospital, and 59 (93.7%) of these patients were discharged alive. Twenty-nine (42.6%) patients with acute diaphragmatic hernia received surgical intervention within 24 hours of trauma, and 26 of 29 (89.7%) patients were discharged alive. An overall acute and chronic perioperative survival rate of 89.7% was observed in dogs and cats that received surgical intervention within 24 hours of admission. Results in 68 dogs and cats that underwent surgery within 24 hours of admission suggested that early surgical intervention for acute diaphragmatic hernia was associated with good perioperative survival rates.
Sandfort, Veit; Johnson, Alistair E W; Kunz, Lauren M; Vargas, Jose D; Rosing, Douglas R
2018-01-01
We sought to evaluate the association of prolonged elevated heart rate (peHR) with survival in acutely ill patients. We used a large observational intensive care unit (ICU) database (Multiparameter Intelligent Monitoring in Intensive Care III [MIMIC-III]), where frequent heart rate measurements were available. The peHR was defined as a heart rate >100 beats/min in 11 of 12 consecutive hours. The outcome was survival status at 90 days. We collected heart rates, disease severity (simplified acute physiology scores [SAPS II]), comorbidities (Charlson scores), and International Classification of Diseases (ICD) diagnosis information in 31 513 patients from the MIMIC-III ICU database. Propensity score (PS) methods followed by inverse probability weighting based on the PS was used to balance the 2 groups (the presence/absence of peHR). Multivariable weighted logistic regression was used to assess for association of peHR with the outcome survival at 90 days adjusting for additional covariates. The mean age was 64 years, and the most frequent main disease category was circulatory disease (41%). The mean SAPS II score was 35, and the mean Charlson comorbidity score was 2.3. Overall survival of the cohort at 90 days was 82%. Adjusted logistic regression showed a significantly increased risk of death within 90 days in patients with an episode of peHR ( P < .001; odds ratio for death 1.79; confidence interval, 1.69-1.88). This finding was independent of median heart rate. We found a significant association of peHR with decreased survival in a large and heterogenous cohort of ICU patients.
Directory of Open Access Journals (Sweden)
Andi Nikhlani
2017-07-01
Full Text Available ABSTRACT The survival rate of blue swimming crabs and the larval metamorphosis processes are still low in hatcheries. The objective of this study was to evaluate the effects of different phytoecdysteroids doses on both the survival and the rate of Blue swimmer crab larvae metamorphosis. The study consisted of four different phytoecdysteroids treatments, namely: control (0 mg/100 g of feed, 1 mg/100 g of feed, 2 mg/100 g of feed, and 4 mg/100 g of feed. Each treatment was replicated three times. The survival rate of the larvae was analyzed through analysis of variance, while the rate of larval metamorphosis was descriptively analyzed. The results showed that the dose of phytoecdysteroid of 2 mg/100 g of artificial feed resulted in the highest survival and the fastest metamorphosis speed of crab larvae for zoea-2 and zoea-3, and the dose of 4 mg/100 g of artificial feed for stadia megalopa and crablet. Keywords: phytoecdysteroids, survival rate, metamorphosis, blue swimming crab ABSTRAK Kelangsungan hidup rajungan dalam pembenihan masih rendah, dan proses metamorfosis larva masih lambat. Tujuan penelitian ini adalah untuk mengevaluasi pengaruh pemberian fitoekdisteroid dosis berbeda terhadap kelangsungan hidup dan kecepatan metamorfosis larva rajungan. Penelitian ini terdiri atas empat perlakuan dosis fitoekdisteroid yang berbeda, yaitu: kontrol (0 mg/100 g pakan, 1 mg/100 g pakan, 2 mg/100 g pakan, dan 4 mg/100 g pakan dengan masing-masing perlakuan dilakukan tiga kali ulangan. Kelangsungan hidup larva dianalisis menggunakan analisis sidik ragam, sedangkan kecepatan metamorfosis larva dianalisis secara deskriptif. Hasil penelitian menunjukkan bahwa dosis fitoekdisteroid sebanyak 2 mg/100 g pakan buatan menghasilkan kelangsungan hidup tertinggi dan proses metamorfosis larva rajungan tercepat untuk stadia zoea-2 dan zoea-3, serta dosis 4 mg/100 g pakan buatan untuk stadia megalopa dan crablet. Kata kunci: fitoekdisteroid, kelangsungan
Dose Rate Experiment at JET for Benchmarking the Calculation Direct One Step Method
International Nuclear Information System (INIS)
Angelone, M.; Petrizzi, L.; Pillon, M.; Villari, R.; Popovichev, S.
2006-01-01
, experimental background data and dose rate, the latter collected during some operation free days in the early phase of the 2006 JET campaign, are compared with the same quantities calculated using the D1S approach. The impact of key parameters (geometrical model, materials impurities, different sets of cross sections) to the calculated dose rates is discussed as well. (author)
Houshyari, Mohammad; Hajalikhani, Farzaneh; Rakhsha, Afshin; Hajian, Parastoo
2015-03-25
In adults, malignant glioma (high-grade glioma) is one of the most common brain tumors. In spite of different types of treatment, the outcome is still not likely to be favorable. The aim of this study was to determine the difference between survival rate in adult patients with high grade glioma treated by radiotherapy only and those treated by a combination of radiotherapy and nitrosurea-based chemotherapy. This study was conducted using the records of 48 patients with grade 3 or 4 of glial brain tumor referred to the radiation-oncology ward of Shohada-e-Tajrish Hospital in Tehran, Iran from 2005 to 2012. The patients had undergone radiotherapy alone or adjuvant chemoradiation with nitrosourea. The median survival of patients after receiving the different types of treatment were evaluated using the Kaplan-Meier method and the log -rank exam. Data were analyzed using univariate analysis for median survival regarding to the patients' age, gender, extent of surgery, Karnofsky performance status (KPS) with the Kaplan-Meier method, and the log-rank exam. We used the Cox-model for multivariate analysis. Records of 48 patients were studied (34 men and 14 women). The mean survival were 18 months for men and 15.2 months for women (P=0.05). Around 58% (28 patients) were more than 50 years old, and 42% (20 patients) were less than 50, and mean survival for the two age groups were 13 and 20 months, respectively (P<0.001). Then, the patients were divided into three groups according to the extent of surgery, i.e., excisional biopsy (11 patients), stereotactic biopsy (22 patients), and resection (15 patients), and the mean survival for the three groups were 14.7, 17.3, and 18.8 months, respectively. There was no significant statistical difference for mean survival between the three groups (P=0.23). The KPS was greater than 70% in 23 patients and less than 70% in 21 patients, and the mean survival for the former and latter groups were 17.6 and 16 months, respectively (P=0
Late development of homoeothermy in mink (Mustela vison) kits - a strategy for maximum survival rate
DEFF Research Database (Denmark)
Tauson, A-H; Chwalibog, André; Tygesen, M P
2006-01-01
and after the experiments and evaporative water losses (EWL) were calculated. When exposed to L temperature, single kits responded with a very low HE until 29 days of age, and groups of kits until 14 days of age. It was not until they reached an age of approximately 6 weeks that single kits showed a clear...... thermoregulatory response to the L temperature by increased HE, whereas groups of kits showed increased HE from 29th day onwards. When kept at H temperature, HE was low initially, but all kits showed elevated HE at 8 days of age, and the metabolic rate was similar for single kits and kits huddling in groups....... Evaporative water losses was higher among single than among groups of kits and slightly lower but more variable for animals at L than at H temperature. It was concluded that mink kits develop functional homoeothermy at an age of close to 6 weeks and that the failure of very young kits to thermoregulate...
DEFF Research Database (Denmark)
Aarestrup, Kim; Baktoft, Henrik; Thorstad, EB
2015-01-01
The marine migration of post-spawning anadromous fish remains poorly understood. The present study examined survival and progression rates of anadromous brown trout Salmo trutta L. after spawning (kelts) during downriver, fjord, and sea migration. Kelts (n = 49) were captured in the Danish River...... completing the reach within 4 d, suggesting that the kelts spent limited time foraging after returning to the fjord. The total survival during the entire marine migration, including the fjord, was a minimum of 29%. Our study provides data that are important for management of anadromous brown trout...
Directory of Open Access Journals (Sweden)
Rutchanee Chotikachinda
2008-10-01
Full Text Available Effects of dietary inactive yeast cell wall on growth performance, survival rate, and immune parameters in pacific white shrimp (Litopenaeus vannamei was investigated. Three dosages of inactive yeast cell wall (0, 1, and 2 g kg-1 were tested in three replicate groups of juvenile shrimps with an average initial weight of 7.15±0.05 g for four weeks. There was no significant difference in final weight, survival rate, specific growth rate, feed conversion ratio, feed intake, protein efficiency ratio, and apparent net protein utilization of each treatments. However, different levels of inactive yeast cell wall showed an effect on certain immune parameters (p<0.05. Total hemocyte counts, granular hemocyte count, and bacterial clearance were better in shrimp fed diets supplemented with 1 and 2 g kg-1 inactive yeast cell wall as compared with thecontrol group.
Forward flux sampling calculation of homogeneous nucleation rates from aqueous NaCl solutions.
Jiang, Hao; Haji-Akbari, Amir; Debenedetti, Pablo G; Panagiotopoulos, Athanassios Z
2018-01-28
We used molecular dynamics simulations and the path sampling technique known as forward flux sampling to study homogeneous nucleation of NaCl crystals from supersaturated aqueous solutions at 298 K and 1 bar. Nucleation rates were obtained for a range of salt concentrations for the Joung-Cheatham NaCl force field combined with the Extended Simple Point Charge (SPC/E) water model. The calculated nucleation rates are significantly lower than the available experimental measurements. The estimates for the nucleation rates in this work do not rely on classical nucleation theory, but the pathways observed in the simulations suggest that the nucleation process is better described by classical nucleation theory than an alternative interpretation based on Ostwald's step rule, in contrast to some prior simulations of related models. In addition to the size of NaCl nucleus, we find that the crystallinity of a nascent cluster plays an important role in the nucleation process. Nuclei with high crystallinity were found to have higher growth probability and longer lifetimes, possibly because they are less exposed to hydration water.
Woods, P.F.
1985-01-01
The survival and growth rates of rainbow trout (Salmo gairdnieri) were concurrently measured with selected limnological characteristics in nine small (surface area Gasterosteus aculeatus) also influenced survival of rainbow trout but their effects were overshadowed by winterkill. Predictive capability was also reduced because of inconsistencies in rankings generated by each of the four limnological variables chosen as indicators of potential biological productivity. A lake ranked low in productivity by one variable was commonly ranked high in productivity by another variable. The survivability of rainbow trout stocked in lakes such as these nine may be a more important indicator of potential biomass production than are indicators of lake fertility. Assessments of a lake 's susceptibility to winterkill and the degree of competition with threespine stickleback are suggested as important topics for additional research. (Author 's abstract)
Tahir, M Ramzan; Tran, Quang X; Nikulin, Mikhail S
2017-05-30
We studied the problem of testing a hypothesized distribution in survival regression models when the data is right censored and survival times are influenced by covariates. A modified chi-squared type test, known as Nikulin-Rao-Robson statistic, is applied for the comparison of accelerated failure time models. This statistic is used to test the goodness-of-fit for hypertabastic survival model and four other unimodal hazard rate functions. The results of simulation study showed that the hypertabastic distribution can be used as an alternative to log-logistic and log-normal distribution. In statistical modeling, because of its flexible shape of hazard functions, this distribution can also be used as a competitor of Birnbaum-Saunders and inverse Gaussian distributions. The results for the real data application are shown. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.
Effects of Water Replacement rate on Growth and Survival of the ...
African Journals Online (AJOL)
The influence of frequency of water replacement on growth performance and survival of the Nile tilapia,Oreochromis niloticus fry of mean 1.14g + 0.00 of the same brood stock reared in a static culture was investigated in the laboratory over a period of forty-two days. There were five treatments namely, treatment A = daily ...
Do pathological fractures influence survival and local recurrence rate in bony sarcomas?
Bramer, J. A. M.; Abudu, A. A.; Grimer, R. J.; Carter, S. R.; Tillman, R. M.
2007-01-01
The influence of pathological fracture on surgical management, local recurrence and survival was established in patients with high grade, localised, extremity osteosarcoma (n=484), chondrosarcoma (n=130) and Ewing's sarcoma (n=156). Limb salvage was possible in 79% of patients with a fracture
Implications of imprecision in kinetic rate data for photochemical model calculations
Energy Technology Data Exchange (ETDEWEB)
Stewart, R W; Thompson, A M [National Aeronautics and Space Administration, Greenbelt, MD (United States). Goddard Space Flight Center
1998-12-31
Evaluation of uncertainties in photochemical model calculations is of great importance to scientists performing assessment modeling. A major source of uncertainty is the measurement imprecision inherent in photochemical reaction rate data that modelers rely on. A rigorous method of evaluating the impact of data imprecision on computational uncertainty is the study of error propagation using Monte Carlo techniques. There are two problems with the current implementation of the Monte Carlo method. First, there is no satisfactory way of accounting for the variation of imprecision with temperature in 1, 2, or 3D models; second, due to its computational expense, it is impractical in 3D model studies. These difficulties are discussed. (author) 4 refs.
Implications of imprecision in kinetic rate data for photochemical model calculations
Energy Technology Data Exchange (ETDEWEB)
Stewart, R.W.; Thompson, A.M. [National Aeronautics and Space Administration, Greenbelt, MD (United States). Goddard Space Flight Center
1997-12-31
Evaluation of uncertainties in photochemical model calculations is of great importance to scientists performing assessment modeling. A major source of uncertainty is the measurement imprecision inherent in photochemical reaction rate data that modelers rely on. A rigorous method of evaluating the impact of data imprecision on computational uncertainty is the study of error propagation using Monte Carlo techniques. There are two problems with the current implementation of the Monte Carlo method. First, there is no satisfactory way of accounting for the variation of imprecision with temperature in 1, 2, or 3D models; second, due to its computational expense, it is impractical in 3D model studies. These difficulties are discussed. (author) 4 refs.
International Nuclear Information System (INIS)
Boccaccini, L.V.
1986-07-01
To take advantages of the semi-implicit computer models - to solve the two phase flow differential system - a proper averaging procedure is also needed for the source terms. In fact, in some cases, the correlations normally used for the source terms - not time averaged - fail using the theoretical time step that arises from the linear stability analysis used on the right handside. Such a time averaging procedure is developed with reference to the bubbly flow regime. Moreover, the concept of mass that must be exchanged to reach equilibrium from a non-equilibrium state is introduced to limit the mass transfer during a time step. Finally some practical calculations are performed to compare the different correlations for the average mass transfer rate developed in this work. (orig.) [de
Helium release rates and ODH calculations from RHIC magnet cooling line failure
Energy Technology Data Exchange (ETDEWEB)
Liaw, C.J.; Than, Y.; Tuozzolo, J.
2011-03-28
A catastrophic failure of the magnet cooling lines, similar to the LHC superconducting bus failure incident, could discharge cold helium into the RHIC tunnel and cause an Oxygen Deficiency Hazard (ODH) problem. A SINDA/FLUINT{reg_sign} model, which simulated the 4.5K/4 atm helium flowing through the magnet cooling system distribution lines, then through a line break into the insulating vacuum volumes and discharging via the reliefs into the RHIC tunnel, had been developed. Arc flash energy deposition and heat load from the ambient temperature cryostat surfaces are included in the simulations. Three typical areas: the sextant arc, the Triplet/DX/D0 magnets, and the injection area, had been analyzed. Results, including helium discharge rates, helium inventory loss, and the resulting oxygen concentration in the RHIC tunnel area, are reported. Good agreement had been achieved when comparing the simulation results, a RHIC sector depressurization test measurement, and some simple analytical calculations.
The simplified convergence rate calculation for salt grit backfilled caverns in rock salt
International Nuclear Information System (INIS)
Navarro, Martin
2013-03-01
Within the research and development project 3609R03210 of the German Federal Ministry for the Environment, Nature Conservation and Nuclear Safety, different methods were investigated, which are used for the simplified calculation of convergence rates for mining cavities in salt rock that have been backfilled with crushed salt. The work concentrates on the approach of Stelte and on further developments based on this approach. The work focuses on the physical background of the approaches. Model specific limitations are discussed and possibilities for further development are pointed out. Further on, an alternative approach is presented, which implements independent material laws for the convergence of the mining cavity and the compaction of the crushed salt backfill.
Systematic comparison of ISOLDE-SC yields with calculated in-target production rates
International Nuclear Information System (INIS)
Lukic, S.; Gevaert, F.; Kelic, A.; Ricciardi, M.V.; Schmidt, K.H.; Yordanov, O.
2006-02-01
Recently, a series of dedicated inverse-kinematics experiments performed at GSI, Darmstadt, has brought an important progress in our understanding of proton and heavy-ion induced reactions at relativistic energies. The nuclear reaction code ABRABLA that has been developed and benchmarked against the results of these experiments has been used to calculate nuclide production cross sections at different energies and with different targets and beams. These calculations are used to estimate nuclide production rates by protons in thick targets, taking into account the energy loss and the attenuation of the proton beam in the target, as well as the low-energy fission induced by the secondary neutrons. The results are compared to the yields of isotopes of various elements obtained from different targets at CERN-ISOLDE with 600 MeV protons, and the overall extraction efficiencies are deduced. The dependence of these extraction efficiencies on the nuclide half-life is found to follow a simple pattern in many different cases. A simple function is proposed to parameterize this behavior in a way that quantifies the essential properties of the extraction efficiency for the element and the target - ion-source system in question. (orig.)
Directory of Open Access Journals (Sweden)
Kukuh Nirmala
2013-11-01
Full Text Available Heavy metals are serious pollutants of the aquatic environment because of their environmental persistence and ability to be accumulated by aquatic organisms. Oreochromis niloticus exposed to 0, 0.16, 0.5, and 1.0 ppm Hg for 30 days. The aim of this study was to determine the influence of mercury in water on survival rate, growth rates, hematological, and histological parameters of Oreochromis niloticus. This study was conducted from Mei to June 2009. The experimental design was arranged in completely randomized design with four treatments and three replications. Stock density was 8 fish/aquarium with mean initial body weight was 15.70±1.13 g. Growth and survival rates of test fish were decreased with increasing the Hg concentration. Red blood cell (RBC count, haematocrit content, and haemoglobin content decreased when compared to the control. The number of white blood cells (WBC increased in mercuric treated fish. The results are statistically significant at p<0.05 level. Keywords:mercury, survival and growth rate, hematology, histopathology, Oreochromis niloticus
International Nuclear Information System (INIS)
Hu, T.A.
2007-01-01
Assess the steady-state flammability level at normal and off-normal ventilation conditions. The methodology of flammability analysis for Hanford tank waste is developed. The hydrogen generation rate model was applied to calculate the gas generation rate for 177 tanks. Flammability concentrations and the time to reach 25% and 100% of the lower flammability limit, and the minimum ventilation rate to keep from 100 of the LFL are calculated for 177 tanks at various scenarios.
van der Heijden, R T; Heijnen, J J; Hellinga, C; Romein, B; Luyben, K C
1994-01-05
Measurements provide the basis for process monitoring and control as well as for model development and validation. Systematic approaches to increase the accuracy and credibility of the empirical data set are therefore of great value. In (bio)chemical conversions, linear conservation relations such as the balance equations for charge, enthalpy, and/or chemical elements, can be employed to relate conversion rates. In a pactical situation, some of these rates will be measured (in effect, be calculated directly from primary measurements of, e.g., concentrations and flow rates), as others can or cannot be calculated from the measured ones. When certain measured rates can also be calculated from other measured rates, the set of equations, the accuracy and credibility of the measured rates can indeed be improved by, respectively, balancing and gross error diagnosis. The balanced conversion rates are more accurate, and form a consistent set of data, which is more suitable for further application (e.g., to calculate nonmeasured rates) than the raw measurements. Such an approach has drawn attention in previous studies. The current study deals mainly with the problem of mathematically classifying the conversion rates into balanceable and calculable rates, given the subset of measured rates. The significance of this problem is illustrated with some examples. It is shown that a simple matrix equation can be derived that contains the vector of measured conversion rates and the redundancy matrix R. Matrix R plays a predominant role in the classification problem. In supplementary articles, significance of the redundancy matrix R for an improved gross error diagnosis approach will be shown. In addition, efficient equations have been derived to calculate the balanceable and/or calculable rates. The method is completely based on matrix algebra (principally different from the graph-theoretical approach), and it is easily implemented into a computer program. (c) 1994 John Wiley & Sons
Controls on Arctic sea ice from first-year and multi-year survival rates
Energy Technology Data Exchange (ETDEWEB)
Hunke, Jes [Los Alamos National Laboratory
2009-01-01
The recent decrease in Arctic sea ice cover has transpired with a significant loss of multi year ice. The transition to an Arctic that is populated by thinner first year sea ice has important implications for future trends in area and volume. Here we develop a reduced model for Arctic sea ice with which we investigate how the survivability of first year and multi year ice control the mean state, variability, and trends in ice area and volume.
Directory of Open Access Journals (Sweden)
Vukajlović Filip N.
2017-01-01
Full Text Available The present study was undertaken to determine survival rate of Plodia interpunctella (Hübner, 1813, reared on different mechanical states of Vizija winter wheat cultivar and Raša winter rye cultivar, previously infested with different beetle pests. Wheat was previously infested with Rhyzopertha dominica, Sitophilus granarius, Oryzaephilus surinamensis and Cryptolestes ferrugineus, while rye was infested only with O. surinamensis. Kernels were tested in three different mechanical states: (A whole undamaged kernels; (B kernels already damaged by pests and (C original storage kernels (mixture of B and C type. No P. interpunctella adult emerged on wheat kernels, while 36 adults developed on rye kernels. The highest abundance reached beetle species who fed with a mixture of kernels damaged by pests and whole undamaged kernels. Development and survival rate of five different storage insect pests depends on type of kernels and there exist significant survivorship correlations among them.
Jones, Samuel B; Burnett, William C; Coile, Nancy C; Mabry, Tom J; Betkouski, M F
1979-01-01
Sesquiterpene lactone glaucolide-A from Vernonia, incorporated in the rearing diets of five species of Lepidoptera, significantly reduced the rate of growth of larvae of the southern armyworm, Spodoptera eridania; fall armyworm, S. frugiperda; and yellowstriped armyworm, S. ornithogalli. Quantitative feeding tests demonstrated that decreased feeding levels and reduced growth resulted from ingestion of a sesquiterpene lactone. Ingestion of glaucolide-A increased the number of days to pupation in four of the species. In the southern armyworm, it significantly reduced pupal weight. Glaucolide-A decidedly reduced percentage of survival of southern and fall armyworms. Yellow woollybear, Diacrisia virginica, and cabbage looper, Trichoplusia ni, larvae were essentially uneffected by the ingestion of the sesquiterpene lactone. Sesquiterpene lactones adversely affect growth rate and survival of certain insects that feed upon plants containing them. They apparently function as defensive products, screening out a portion of the potential herbivores.
International Nuclear Information System (INIS)
Shao Chunlin; Gui Qifu; Yu Zengliang
1995-01-01
The main characteristic of the low energy ions mutation is its mass deposition effect. Basing on the theory of 'double strand breaking' and the 'mass deposition effect', the authors suggests that the mass deposition products can repair or further damage the double strand breaking of DNA. According to this consideration the dose effect model of the survival rate of organism irradiated by low energy of N + ion beam is deduced as: S exp{-p[αφ + βφ 2 -Rφ 2 exp(-kφ)-Lφ 3 exp(-kφ)]}, which can be called 'mass effect model'. In the low energy ion beam mutation, the dose effects of many survival rates that can not be imitated by previous models are successfully imitated by this model. The suitable application fields of the model are also discussed
Energy Technology Data Exchange (ETDEWEB)
van Beuningen, D.; Streffer, C.; Bertholdt, G.
1981-09-01
After neutron and X-ray irradiation and combined X-ray irradiation and hyperthermia (3 hours, 42/sup 0/C), the survival rate of human melanoma cells was measured by means of the colony formation test and compared to the formation of micronuclei. Neutrons had a stronger effect on the formation of micronuclei than the combination of X-rays and hyperthermia. X-rays had the lowest effect. The dose effect curve showed a break at that dose level at which a reduction of cells was observed in the cultures. A good relation between survival rate and formation of micronuclei was found for the X-ray irradiation, but not for the neutron irradiation and the combined treatment. These observations are discussed. At least for X-rays, the micronucleus test has turned out to be a good screening method for the radiosensitivity of a biologic system.
Sherbini, S; Tamasanis, D; Sykes, J; Porter, S W
1986-12-01
A program was developed to calculate the exposure rate resulting from airborne gases inside a reactor containment building. The calculations were performed at the location of a wall-mounted area radiation monitor. The program uses Monte Carlo techniques and accounts for both the direct and scattered components of the radiation field at the detector. The scattered component was found to contribute about 30% of the total exposure rate at 50 keV and dropped to about 7% at 2000 keV. The results of the calculations were normalized to unit activity per unit volume of air in the containment. This allows the exposure rate readings of the area monitor to be used to estimate the airborne activity in containment in the early phases of an accident. Such estimates, coupled with containment leak rates, provide a method to obtain a release rate for use in offsite dose projection calculations.
Zembic, Anja; Tahmaseb, Ali; Jung, Ronald E; Wismeijer, Daniel
2017-07-01
To assess implant survival rates and peri-implant bone loss of 2 titanium-zirconium implants supporting maxillary overdentures at 1 year of loading. Twenty maxillary edentulous patients (5 women and 15 men) being dissatisfied with their complete dentures were included. In total, 40 diameter-reduced titanium-zirconium implants were placed in the anterior maxilla. Local guided bone regeneration (GBR) was allowed if the treatment did not compromise implant stability. Following 3 to 5 months of healing, implant-supported overdentures were inserted on two ball anchors. Implants and overdentures were assessed at 1, 2, 4, and 8 weeks after implant insertion and 2, 4, and 12 months after insertion of overdentures (baseline). Standardized radiographs were taken at implant loading and 1 year. Implant survival rates and bone loss were the primary outcomes. Nineteen patients (1 dropout) with 38 implants were evaluated at a mean follow-up of 1.1 years (range 1.0-1.7 years). One implant failed resulting in an implant survival rate of 97.3%. There was a significant peri-implant bone loss of the implants at 1 year of function (mean, 0.7 mm, SD = 1.1 mm; median: 0.48 mm, IQR = 0.56 mm). There was a high 1-year implant survival rate for edentulous patients receiving 2 maxillary implants and ball anchors as overdenture support. However, several implants exhibited an increased amount of bone loss of more than 2 mm. Overdentures supported by 2 maxillary implants should thus be used with caution as minimally invasive treatment for specific patients encountering problems with their upper dentures until more long-term data is available. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Juarez-Moreno, Karla; Mejía-Ruiz, Claudio Humberto; Díaz, Fernando; Reyna-Verdugo, Horacio; Re, Ana Denisse; Vazquez-Felix, Edgar F; Sánchez-Castrejón, Edna; Mota-Morales, Josué D; Pestryakov, Alexey; Bogdanchikova, Nina
2017-02-01
White spot syndrome virus (WSSV) is highly lethal and contagious in shrimps; its outbreaks causes an economic crisis for aquaculture. Several attempts have been made to treat this disease; however, to date, there is no effective cure. Because of their antimicrobial activities, silver nanoparticles (AgNPs) are the most studied nanomaterial. Although the antiviral properties of AgNPs have been studied, their antiviral effect against viral infection in aquaculture has not been reported. The AgNPs tested herein are coated with polyvinylpyrrolidone (PVP) and possess multiple international certifications for their use in veterinary and human applications. The aim of this work was to evaluate the survival rate of juvenile white shrimps (Litopenaeus vannamei) after the intramuscular administration of AgNPs. For this, different concentrations of metallic AgNPs and PVP alone were injected into the organisms. After 96 h of administration, shrimp survival was more than 90% for all treatments. The oxygen consumption routine rate and total hemocyte count remained unaltered after AgNP injection, reflecting no stress caused. We evaluated whether AgNPs had an antiviral effect in shrimps infected with WSSV. The results revealed that the survival rate of WSSV-infected shrimps after AgNP administration was 80%, whereas the survival rate of untreated organisms was only 10% 96 h after infection. These results open up the possibility to explore the potential use of AgNPs as antiviral agents for the treatment of diseases in aquaculture organisms, particularly the WSSV in shrimp culture. Copyright © 2016 Elsevier Ltd. All rights reserved.
2013-06-24
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2012-03-27
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2011-07-13
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2010-04-19
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2013-10-23
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2010-06-30
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2012-09-27
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2010-09-27
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2011-10-19
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2012-01-17
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2013-04-04
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2010-01-05
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2011-01-13
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2012-06-26
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2011-04-13
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Directory of Open Access Journals (Sweden)
Jessica Porcelan
2012-01-01
Full Text Available Caenorhabditis elegans unc-13 mutants express decreased neuronal activity and thus are a good model strain for examining defective nervous systems. These unc-13 mutants as well as wild type N2 strains, show rapid mortality when under oxidative stress. However, the antioxidant vitamin E may prolong survival in unc-13 mutant and N2 strains under oxidative stress. The addition of vitamin E to organisms under oxidative stress has a protective effect in both N2 and unc-13 C. elegans strains. Interestingly, vitamin E resulted in a greater increase in survival rate in N2 worms than with unc-13 mutant worms. While both strains displayed lower mortality rates with the addition of vitamin E, this finding suggests that vitamin E more efficiently increases survival rates of C. elegans with typical nervous system function. The efficacy of vitamin E implies that use of antioxidants may lessen the damage caused by oxidative stress in both N2 and mutant worms.
Directory of Open Access Journals (Sweden)
M. I. Volkova
2014-11-01
Full Text Available Objective: to analyze the impact of surgical volume on functional results and cardiospecific survival rates in patients with clinically localized renal carcinoma.Subjects and methods. Four hundred and fifty-three patients with pT1–3aN0M0 renal cell carcinoma and normally functioning secondkidney who had undergone radical nephrectomy (n = 226 (49.9 % or kidney resection (n = 227 (50.1 % were selected for the investigation. The patient groups who had undergone different-volume operations were matched for gender, age, body mass index (BMI, side of involvement, tumor sizes, and baseline glomerular filtration rate (GFR (p > for all. The median baseline Charlson index and the rate of ASA classes III–IV operative risk were significantly higher in candidates for radical nephrectomy (p < 0.05 for all, the rate of diseases affecting kidney function, pT1a category, and G1 anaplasia were higher in the kidney resection group (p < 0.0001. The median follow-up was 50 (12–224 months.Results. Within 28 days postsurgery, the rate of acute renal dysfunction (ARD was 36.2 %. The independent risk factors of ARD were kidney resection (risk ratio (RR = 0.210; 95 % confidence interval (CI 0.115–0.288; р < 0.0001 and ischemia time (RR = 0.012; 95 % CI 0.004–0.021; p = 0.004. The degree of ARD after kidney resection was significantly lower than that following radical nephrectomy (p < 0.0001. In the late postoperative period, the incidence of chronic kidney disease (CKD Stage ≥ III was 38.4 %. Its independent risk factors were low baseline GFR (RR = 0.003; 95 % CI 0.002–0.005; p < 0.0001, radical nephrectomy (RR = 0.195; 95 % CI 0.093–0.298; p < 0.0001, and ARD (RR = 0.281; 95 % CI 0.187–0.376; p = 0.0001. Ten-year specific and cardiospecific survival rates in all the patients were 98.5 and 94.9 %, respectively, and unrelated to surgical volume. The independent predictors of poor cardiospecific survival were BMI, Charlson index, and ASA risk
Directory of Open Access Journals (Sweden)
M. I. Volkova
2014-01-01
Full Text Available Objective: to analyze the impact of surgical volume on functional results and cardiospecific survival rates in patients with clinically localized renal carcinoma.Subjects and methods. Four hundred and fifty-three patients with pT1–3aN0M0 renal cell carcinoma and normally functioning secondkidney who had undergone radical nephrectomy (n = 226 (49.9 % or kidney resection (n = 227 (50.1 % were selected for the investigation. The patient groups who had undergone different-volume operations were matched for gender, age, body mass index (BMI, side of involvement, tumor sizes, and baseline glomerular filtration rate (GFR (p > for all. The median baseline Charlson index and the rate of ASA classes III–IV operative risk were significantly higher in candidates for radical nephrectomy (p < 0.05 for all, the rate of diseases affecting kidney function, pT1a category, and G1 anaplasia were higher in the kidney resection group (p < 0.0001. The median follow-up was 50 (12–224 months.Results. Within 28 days postsurgery, the rate of acute renal dysfunction (ARD was 36.2 %. The independent risk factors of ARD were kidney resection (risk ratio (RR = 0.210; 95 % confidence interval (CI 0.115–0.288; р < 0.0001 and ischemia time (RR = 0.012; 95 % CI 0.004–0.021; p = 0.004. The degree of ARD after kidney resection was significantly lower than that following radical nephrectomy (p < 0.0001. In the late postoperative period, the incidence of chronic kidney disease (CKD Stage ≥ III was 38.4 %. Its independent risk factors were low baseline GFR (RR = 0.003; 95 % CI 0.002–0.005; p < 0.0001, radical nephrectomy (RR = 0.195; 95 % CI 0.093–0.298; p < 0.0001, and ARD (RR = 0.281; 95 % CI 0.187–0.376; p = 0.0001. Ten-year specific and cardiospecific survival rates in all the patients were 98.5 and 94.9 %, respectively, and unrelated to surgical volume. The independent predictors of poor cardiospecific survival were BMI, Charlson index, and ASA risk
Experimental validation of calculated capture rate for nucleus involved in fuel cycle
International Nuclear Information System (INIS)
Benslimane-Bouland, A.
1997-09-01
The framework of this study was the evaluation of the nuclear data requirements for Actinides and Fission Products applied to current nuclear reactors as well as future applications. This last item includes extended irradiation campaigns, 100 % Mixed Oxide fuel, transmutation or even incineration. The first part of this study presents different types of integral measurements which are available for capture rate measurements, as well as the methods used for reactor core calculation route design and nuclear data library validation. The second section concerns the analysis of three specific irradiation experiments. The results have shown the extent of the current knowledge on nuclear data as well as the associated uncertainties. The third and last section shows both the coherency between all the results, and the statistical method applied for nuclear data library adjustment. A relevant application of this method has demonstrated that only specifically chosen integral experiments can be of use for the validation of nuclear data libraries. The conclusion is reached that even if co-ordinated efforts between reactor and nuclear physicists have made possible a huge improvement in the knowledge of capture cross sections of the main nuclei such as uranium and plutonium, some improvements are currently necessary for the minor actinides (Np, Am and Cm). Both integral and differential measurements are recommended to improve the knowledge of minor actinide cross sections. As far as integral experiments are concerned, a set of criteria to be followed during the experimental conception have been defined in order to both reduce the number of required calculation approximations, and to increase as much as possible the maximum amount of extracted information. (author)
Rachmawati, D.; Samidjan, I.
2018-04-01
The purpose of this study was to determine the effect of adding phytase enzyme in the feed on digestibility of feed, efficiency of feed utilization, relative growth rate and survival rate of Common carp (Cyprinus carpio). Fish samples in this research were Common carp with an average - weight of 3.34 ± 0,16 g/fish. The treatments were adding the phytase enzyme in the feed with the different level of doses. Those were A (0 U kg-1 feed), B (500 U kg-1 feed), C (1.000 U kg-1 feed g) and D (1.500 U kg-1 feed). Observation was conducted on digestibility of protein (ADCP), digestibility of phosphor (ADCF), efficiency of feed utilization (EFU), relative growth rate (RGR), protein efficiency ratio (PER), feed conversion ratio (FCR), survival rate (SR) and water quality parameters. The results show that the addition of phytase enzyme significantly (P0.05) affected on SR of common carp. Based on results, it was concluded that optimum doses of phytase enzyme feed in terms of digestibility of feed, efficiency utilization of Feed and growth rate of Common carp ranges from 943 to 1100 U kg-1 feed
Avolio, Alfonso W; Agnes, Salvatore; Cillo, Umberto; Lirosi, Maria C; Romagnoli, Renato; Baccarani, Umberto; Zamboni, Fausto; Nicolini, Daniele; Donataccio, Matteo; Perrella, Alessandro; Ettorre, Giuseppe M; Romano, Marina; Morelli, Nicola; Vennarecci, Giovanni; de Waure, Chiara; Fagiuoli, Stefano; Burra, Patrizia; Cucchetti, Alessandro
2012-03-01
Optimization of donor-recipient match is one of the exciting challenges in liver transplantation. Using algorithms obtained by the Italian D-MELD study (5256 liver transplants, 21 Centers, 2002-2009 period), a web-based survival calculator was developed. The calculator is available online at the URL http://www.D-MELD.com. The access is free. Registration and authentication are required. The website was developed using PHP scripting language on HTML platform and it is hosted by the web provider Aruba.it. For a given donor (expressed by donor age) and for three potential recipients (expressed by values of bilirubin, creatinine, INR, and by recipient age, HCV, HBV, portal thrombosis, re-transplant status), the website calculates the patient survival at 90days, 1year, 3years, and allows the identification of possible unsustainable matches (i.e. donor-recipient matches with predicted patient survival less than 50% at 5 years). This innovative approach allows the selection of the best recipient for each referred donor, avoiding the allocation of a high-risk graft to a high-risk recipient. The use of the D-MELD.com website can help transplant surgeons, hepatologists, and transplant coordinators in everyday practice of matching donors and recipients, by selecting the more appropriate recipient among various candidates with different prognostic factors. © 2012 The Authors. Transplant International © 2012 European Society for Organ Transplantation.
Gupta, Digant; Patel, Kamal; Lis, Christopher G
2015-09-04
We have previously reported that higher patient satisfaction (PS) with service quality is associated with favorable survival outcomes in a variety of cancers. However, we argued that patients with greater satisfaction might be the ones with better self-rated health (SRH), a recognized predictor of cancer survival. We therefore investigated whether SRH can supersede patient satisfaction as a predictor of survival in prostate cancer. Nine hundred seventeen prostate cancer treated at four Cancer Treatment Centers of America(®) hospitals between July 2011 and March 2013. PS was measured on a 7-point scale ranging from "completely dissatisfied" to "completely satisfied". SRH was measured on a 7-point scale ranging from "very poor" to "excellent". Both were dichotomized into two categories: top box response (7) versus all others (1-6). Patient survival was the primary end point. Cox regression was used to evaluate the association between PS and survival controlling for covariates. The response rate for this study was 72%. Majority of patients (n = 517) had stage II disease. Seven hundred eighty-seven (85.8%) patients were "completely satisfied". Three hundred nineteen (34.8%) patients had "excellent" SRH. There was a weak but significant correlation between satisfaction and SRH (Kendall's tau b = 0.18; p < 0.001). On univariate analysis, "completely satisfied" patients had a significantly lower risk of mortality (HR = 0.46; 95% CI: 0.25-0.85; p = 0.01). Similarly, patients with "excellent" SRH had a significantly lower risk of mortality (HR = 0.25; 95% CI: 0.11-0.58; p = 0.001). On multivariate analysis, SRH was found to be a significant predictor of survival (HR = 0.31; 95% CI: 0.12-0.79; p = 0.01) while patient satisfaction was not (HR = 0.76; 95% CI: 0.40-1.5; p = 0.40). SRH supersedes patient satisfaction with service quality as a predictor of survival in prostate cancer. SRH should be used as a control variable in analyses involving patient satisfaction as a
DEFF Research Database (Denmark)
Draper, Elizabeth S; Zeitlin, Jennifer; Fenton, Alan C
2008-01-01
OBJECTIVE: To investigate the variation in the survival rate and the mortality rates for very preterm infants across Europe. DESIGN: A prospective birth cohort of very preterm infants for ten geographically defined European regions during 2003 followed to discharge home from hospital. PARTICIPANTS......: All deliveries from 22+0 to 31+6 weeks gestation. MAIN OUTCOME MEASURE: All outcomes of pregnancy by gestational age group, including termination of pregnancy for congenital anomalies and other reasons, ante-partum stillbirth, intra-partum stillbirth, labour ward death, death after admission...
Marquardt, Pascal; Strub, Jörg Rudolf
2006-04-01
The aim of this prospective clinical study was to evaluate the survival rates of IPS Empress 2 (Ivoclar Vivadent) all-ceramic crowns and fixed partial dentures (FPDs) after an observation period of up to 5 years. Forty-three patients (19 women and 24 men) were included in this study. The patients were treated with a total of 58 adhesive bonded IPS Empress 2 restorations. A total of 27 single crowns were placed on molars and premolars, and 31 three-unit FPDs were placed in the anterior and premolar regions. Clinical follow-up examinations took place at 6, 12, 24, 36, 48, and 60 months after insertion. Statistical analysis of the data was calculated using the Kaplan-Meier method. Results of the 50-month analysis (interquartile range, 33 to 61 months) showed that the survival rate was 100% for crowns and 70% for FPDs. Six failures that occurred exclusively in the three-unit FPDs were observed. Framework fractures were recorded in three FPD units where the connector dimensions did not meet the manufacturer specifications. Only one FPD exhibited an irreparable partial veneer fracture, and 2 FPDs showed evidence of biologic failures. The accuracy of fit and esthetic parameters were clinically satisfactory for crowns and FPDs. The results of this 5-year clinical evaluation suggest that IPS Empress 2 ceramic is an appropriate material for the fabrication of single crowns. Because of the reduced survival rates, strict conditions should be considered before the use of IPS Empress 2 material for the fabrication of three-unit FPDs.
Energy Technology Data Exchange (ETDEWEB)
Wang, Zhi [State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu 610041 (China); Department of Bone and Joint Surgery, The affiliated hospital of Luzhou Medical College, Luzhou 646000 (China); Qing, Quan [Sichuan College of Traditional Chinese Medicine, Mianyang 621000 (China); Regenerative Medicine Research Center, West China Hospital of Sichuan University, Chengdu 610041 (China); Chen, Xi; Liu, Cheng-Jun; Luo, Jing-Cong [State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu 610041 (China); Hu, Jin-Lian [Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hong Kong (China); Qin, Ting-Wu, E-mail: tingwuqin@hotmail.com [State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu 610041 (China)
2016-12-01
Highlights: • The shapes of tenocytes varied when seeded on different surface of scaffolds. • Tenocytes were flat on smooth surface and spindle on micro-grooved surface. • Tenocytes were ellipse or spindle on porous surface. • Tenocytes got varying adhesion shape and elongation index on varying surfaces. • The tenocyte survival on porous surface was superior to the other two groups. - Abstract: The purpose of this study was to investigate the effects of scaffold surface morphology on cell adhesion and survival rate in vitreous cryopreservation of tenocyte-scaffold constructs. Tenocytes were obtained from tail tendons of rats. Polydimethylsiloxane (PDMS) was used to fabricate three types of scaffolds with varying surface morphological characteristics, i.e., smooth, micro-grooved, and porous surfaces, respectively. The tenocytes were seeded on the surfaces of the scaffolds to form tenocyte-scaffold constructs. The constructs were cryopreserved in a vitreous cryoprotectant (CPA) with a multi-step protocol. The cell adhesion to scaffolds was observed with electronic scanning microscopy (SEM). The elongation index of the living tenocytes and ratio of live/dead cell number were examined based on a live/dead dual fluorescent staining technique, and the survival rate of tenocytes was studied with flow cytometry (FC). The results showed the shapes of tenocytes varied between the different groups: flat or polygonal (on smooth surface), spindle (on micro-grooved surface), and spindle or ellipse (on porous surface). After thawing, the porous surface got the most living tenocytes and a higher survival rate, suggesting its potential application for vitreous cryopreservation of engineered tendon constructs.
International Nuclear Information System (INIS)
Hinton, T.G.; Coughlin, D.P.; Marsh, L.C.; Yi, Yi; Winn, R.
2004-01-01
A renewed international interest in the effects on biota from low dose rate irradiation has recently occurred. Much of that interest is centered on the relevance of previously accepted dose rate guidelines (e.g. 10 mGy d -1 for aquatic biota) suggested by the ICRP and IAEA. All parties concerned seem to agree that additional data are needed on population level impacts from chronic low-level exposures to radionuclides. Using a Low Dose Rate Irradiation Facility (LoDIF), we conducted an experiment on the fecundity, fertility and hatchling survival of Japanese Rice Fish (medaka, Oryzias latipes). Fish were exposed externally to 137 Cs from juvenile through adulthood at mean dose rates of 3.5, 35 and 350 mGy d -1 . Fish were bred at maturity and the following endpoints were examined: 1) the number of eggs produced; 2) the percent of eggs that hatched; and 3) the survival of hatchlings 20-days post hatch. The influence of gender was examined by breeding irradiated males with control females; control males with irradiated females; irradiated males with irradiated females; and control males with control females. The data contribute to our understanding the impacts of low dose rate irradiation. (author)
Cappon, Giacomo; Marturano, Francesca; Vettoretti, Martina; Facchinetti, Andrea; Sparacino, Giovanni
2018-05-01
The standard formula (SF) used in bolus calculators (BCs) determines meal insulin bolus using "static" measurement of blood glucose concentration (BG) obtained by self-monitoring of blood glucose (SMBG) fingerprick device. Some methods have been proposed to improve efficacy of SF using "dynamic" information provided by continuous glucose monitoring (CGM), and, in particular, glucose rate of change (ROC). This article compares, in silico and in an ideal framework limiting the exposition to possibly confounding factors (such as CGM noise), the performance of three popular techniques devised for such a scope, that is, the methods of Buckingham et al (BU), Scheiner (SC), and Pettus and Edelman (PE). Using the UVa/Padova Type 1 diabetes simulator we generated data of 100 virtual subjects in noise-free, single-meal scenarios having different preprandial BG and ROC values. Meal insulin bolus was computed using SF, BU, SC, and PE. Performance was assessed with the blood glucose risk index (BGRI) on the 9 hours after meal. On average, BU, SC, and PE improve BGRI compared to SF. When BG is rapidly decreasing, PE obtains the best performance. In the other ROC scenarios, none of the considered methods prevails in all the preprandial BG conditions tested. Our study showed that, at least in the considered ideal framework, none of the methods to correct SF according to ROC is globally better than the others. Critical analysis of the results also suggests that further investigations are needed to develop more effective formulas to account for ROC information in BCs.
Calculations for energies, transition rates, and lifetimes in Al-like Kr XXIV
Zhang, C. Y.; Si, R.; Liu, Y. W.; Yao, K.; Wang, K.; Guo, X. L.; Li, S.; Chen, C. Y.
2018-05-01
Using the second-order many-body perturbation theory (MBPT) method, a complete and accurate data set of excitation energies, lifetimes, wavelengths, and electric dipole (E1), magnetic dipole (M1), electric quadrupole (E2), and magnetic quadrupole (M2) line strengths, transition rates, and oscillator strengths for the lowest 880 levels arising from the 3l3 (0 ≤ l ≤ 2), 3l2 4l‧ (0 ≤ l ≤ 2, 0 ≤l‧ ≤ 3), 3s2 5 l (0 ≤ l ≤ 4), 3p2 5 l (0 ≤ l ≤ 1), and 3s3p5 l (0 ≤ l ≤ 4) configurations in Al-like Kr XXIV is provided. Comparisons are made with available experimental and theoretical results. Our calculated energies are expected to be accurate enough to facilitate identifications of observed lines involving the n = 4 , 5 levels. The complete data set is also useful for modeling and diagnosing fusion plasma.
Effect of temperature on growth, survival and respiratory rate of larval allis shad Alosa alosa
Directory of Open Access Journals (Sweden)
Hundt M.
2015-01-01
Full Text Available Prior species distribution models identified temperature as one of the most important environmental variables defining the present and future distribution of anadromous allis shad (Alosa alosa. The current study analysed effects of temperature on the recruitment-potential of allis shad by investigating growth and survival at 16, 20, 24 and 28 °C during a ten day rearing trial and by measuring mass-specific respiration. Highest growth in length was at 28 °C; growth at 16 °C was minimal. At the end of the rearing-period, no significant differences in survival between tested rearing-temperatures were found. Exposure to temperatures of 13 to 30 °C and subsequent measurement of mass-specific respiration revealed tolerance of temperatures up to 30 °C and a lower temperature limitation close to 16 °C. After acclimatization of larvae to temperatures ranging from 16−28 °C for 10 days, Q10-values of mass-specific respiration indicated a high adaptive capacity to increasing temperatures, but also the ability to adapt to temperatures as low as 16 °C. Our results indicate that the predicted temperature sensitivity of A. alosa cannot be explained by a direct physiological relationship. The obtained results can help to improve predictive modelling and the conservation of allis shad throughout its current distribution range.
Effect of Salinity Adaptation Technique on Survival and Growth Rate of Patin Catfish, Pangasius sp.
Directory of Open Access Journals (Sweden)
K. Nirmala
2007-01-01
Full Text Available This study was carried out to determine the effect of salinity adaptation techniques on growth and survival of patin catfish Pangasius sp. fry. Fry of 1.5-2.0 inch in length were reared in the water with different of the initial salinity of 1, 2, 3, 4 and 5 ppt. Salinity was then daily increased by duplicated the initial water salinity until fish died. The results of study showed that fry could survive by initial salinity adaptation of 1 ppt and then increasing the salinity by 1 ppt/day to reach 27 ppt. In the other treatments, all fry died after the salinity reach 18-25 ppt. Keywords: patin catfish, Pangasius, adaptation, salinity ABSTRAK Penelitian ini bertujuan untuk mengetahui pengaruh teknik adaptasi salinitas terhadap pertumbuhan dan kelangsungan hidup benih ikan patin Pangasius sp. Benih patin ukuran 1,5-2 inci dipelihara pada salinitas awal berbeda, yaitu 1, 2, 3, 4 dan 5 ppt. Salinitas air pemeliharaan ditingkatkan kelipatan dari salinitas awal setiap hari hingga ikan mati. Hasil penelitian menunjukkan bahwa adaptasi salinitas awal 1 ppt dan peningkatan sebesar 1ppt/hari menyebabkan ikan dapat bertahan hidup sampai pada salinitas 27 ppt. Pada perlakuan lainnya, benih ikan mengalami kematian masal ketika salinitas mencapai 18-25 ppt. Kata kunci: ikan patin, Pangasius, adaptasi, salinitas
Directory of Open Access Journals (Sweden)
Ranna Chou
2014-01-01
Full Text Available We investigated the influence of maternal salt restriction during mating or gestation on birth rate and offspring growth in Dahl salt-sensitive rats (DS. DS were divided into 5 groups: DS fed a low-salt (0.3% NaCl, w/w (DS-low or high-salt (4% NaCl, w/w diet (DS-high during mating and DS-high or DS-low during gestation, and DS fed regular chow (0.75% NaCl, w/w (DS-regular throughout mating and gestation. During the unspecified periods, the rats were given regular chow. DS-low during mating delivered fewer infants than high-salt mothers (P<0.05. The birth rate on regular chow was 87%. Six out of 11 DS-low rats during pregnancy produced pups while the rats fed a high-salt diet all delivered pups (P<0.025. The pup survival rate was 67% for high-salt mothers during mating and 54% for mothers on a low-salt diet. The pup survival rate was 95% for mothers on a high-salt diet during pregnancy and 64% for mothers on a low-salt diet (P<0.0001. Seven out of 8 DS-regular rats during mating delivered 59 neonates. However, 66% of the neonates survived. A low-salt diet during mating or pregnancy lowers birth rate and the neonates from low-salt mothers during pregnancy were more likely to die than those from high-salt mothers.
DEFF Research Database (Denmark)
van Harrevelt, Rob; Honkala, Johanna Karoliina; Nørskov, Jens Kehlet
2005-01-01
Quantum-mechanical calculations of the reaction rate for dissociative adsorption of N-2 on stepped Ru(0001) are presented. Converged six-dimensional quantum calculations for this heavy-atom reaction have been performed using the multiconfiguration time-dependent Hartree method. A potential...
45 CFR 261.36 - Do welfare reform waivers affect the calculation of a State's participation rates?
2010-10-01
..., DEPARTMENT OF HEALTH AND HUMAN SERVICES ENSURING THAT RECIPIENTS WORK What Are the Work Activities and How Do They Count? § 261.36 Do welfare reform waivers affect the calculation of a State's participation rates... 45 Public Welfare 2 2010-10-01 2010-10-01 false Do welfare reform waivers affect the calculation...
DEFF Research Database (Denmark)
Draper, Elizabeth S; Zeitlin, Jennifer; Fenton, Alan C
2008-01-01
OBJECTIVE: To investigate the variation in the survival rate and the mortality rates for very preterm infants across Europe. DESIGN: A prospective birth cohort of very preterm infants for ten geographically defined European regions during 2003 followed to discharge home from hospital. PARTICIPANTS...... to directly compare international statistics for mortality in very preterm infants, data collection needs to be standardised. We believe that the standard point of comparison should be using all those infants alive at the onset of labour as the denominator for comparisons of mortality rates for very preterm...... for NIC. For babies rates to discharge from NIC for very preterm deliveries and in the timing of death across the MOSAIC regions. In order...
International Nuclear Information System (INIS)
Paschoa, A.S.; Baptista, G.B.
1977-01-01
A method for the calculation of upper limit internal alpha dose rates to aquatic organisms is presented. The mean alpha energies per disintegration of radionuclides of interest are listed to be used in standard methodologies to calculate dose to aquatic biota. As an application, the upper limits for the alpha dose rates from 239 Pu to the total body of plankton are estimated based on data available in open literature [pt
International Nuclear Information System (INIS)
Lee, Heon; Jin, Gong Yong; Han, Young Min; Chung, Gyung Ho; Lee, Yong Chul; Kwon, Keun Sang; Lynch, David
2012-01-01
Purpose: We retrospectively compared the survival rate in patients with non-small-cell lung cancer (NSCLC) treated with radiofrequency ablation (RFA), surgery, or chemotherapy according to lung cancer staging. Materials and Methods: From 2000 to 2004, 77 NSCLC patients, all of whom had WHO performance status 0–2 and were >60 years old, were enrolled in a cancer registry and retrospectively evaluated. RFA was performed on patients who had medical contraindications to surgery/unsuitability for surgery, such as advanced lung cancer or refusal of surgery. In the RFA group, 40 patients with inoperable NSCLC underwent RFA under computed tomography (CT) guidance. These included 16 patients with stage I to II cancer and 24 patients with stage III to IV cancer who underwent RFA in an adjuvant setting. In the comparison group (n = 37), 13 patients with stage I to II cancer underwent surgery; 18 patients with stage III to IV cancer underwent chemotherapy; and 6 patients with stage III to IV cancer were not actively treated. The survival curves for RFA, surgery, and chemotherapy in these patients were calculated using Kaplan–Meier method. Results: Median survival times for patients treated with (1) surgery alone and (2) RFA alone for stage I to II lung cancer were 33.8 and 28.2 months, respectively (P = 0.426). Median survival times for patients treated with (1) chemotherapy alone and (2) RFA with chemotherapy for stage III to IV cancer were 29 and 42 months, respectively (P = 0.03). Conclusion: RFA can be used as an alternative treatment to surgery for older NSCLC patients with stage I to II inoperable cancer and can play a role as adjuvant therapy with chemotherapy for patients with stage III to IV lung cancer.
Dose-rate effects on the cell cycle and survival of S3 HeLa and V79 cells
International Nuclear Information System (INIS)
Mitchell, J.B.; Bedford, J.S.; Bailey, S.M.
1979-01-01
The effects of continuous irradiation at different dose rates on the cell cycle and on cell survival were studied using synchronized S3 HeLa and V79 cells. The minimum dose rate necessary to stop cell division was found to be approximately 23 rad/hr for HeLa cells and 270 rad/hr for V79 cells. For dose rates that stop cell division, cells progress through G 1 and S, with a small delay in the S phase, and are blocked in G 2 . Appreciable mitotic accumulation was observed for HeLa cells at dose rates which stopped cell division. By comparison, much less mitotic accumulation was observed for V79 cells over a range of dose rates from 37 to 270 rad/hr. Minimum mitotic delays for a variety of dose rates were determined for both cell lines. S3 HeLa cells are much more sensitive in this respect than V79 cells; however, it appeared that for higher dose rates the minimum mitotic delay in HeLa cells asymptotically approached a value of about 35 hr. In addition to the qualitative differences observed for the two cell lines in regard to mitotic accumulation, HeLa cells accumulated for prolonged periods in the presence of colcemid while V79 cells were blocked for only a few hours, HeLa cells show a dramatic effect of redistribution of cells into sensitive phases of the cell cycle during exposure, which was reflected in the survival curves at low dose rate. More cell killing per unit dose was observed at 37 than at 74 rad/hr
International Nuclear Information System (INIS)
Estrela-Lima, Alessandra; Araújo, Márcio SS; Costa-Neto, João M; Teixeira-Carvalho, Andréa; Barrouin-Melo, Stella M; Cardoso, Sergio V; Martins-Filho, Olindo A; Serakides, Rogéria; Cassali, Geovanni D
2010-01-01
The immune system plays an important role in the multifactorial biologic system during the development of neoplasias. However, the involvement of the inflammatory response in the promotion/control of malignant cells is still controversial, and the cell subsets and the mechanisms involved are poorly investigated. The goal of this study was to characterize the clinical-pathological status and the immunophenotyping profile of tumor infiltrating lymphocytes and their association with the animal survival rates in canine mammary carcinomas. Fifty-one animals with mammary carcinomas, classified as carcinomas in mixed tumors-MC-BMT = 31 and carcinomas-MC = 20 were submitted to systematic clinical-pathological analysis (tumor size; presence of lymph node and pulmonary metastasis; clinical stage; histological grade; inflammatory distribution and intensity as well as the lymphocytic infiltrate intensity) and survival rates. Twenty-four animals (MC-BMT = 16 and MC = 8) were elected to the immunophenotypic study performed by flow cytometry. Data analysis demonstrated that clinical stage II-IV and histological grade was I more frequent in MC-BMT as compared to MC. Univariate analysis demonstrated that the intensity of inflammation (moderate/intense) and the proportion of CD4 + (≥ 66.7%) or CD8 + T-cells (<33.3%) were not associated with worse survival rate. Multivariate analysis demonstrated that only lymphocytic infiltrate intensity ≥ 600 (P = 0.02) remained as independent prognostic factor. Despite the clinical manifestation, the lymphocytes represented the predominant cell type in the tumor infiltrate. The percentage of T-cells was higher in animals with MC-BMT without metastasis, while the percentage of B-lymphocytes was greater in animals with metastasized MC-BMT (P < 0.05). The relative percentage of CD4 + T-cells was significantly greater in metastasized tumors (both MC-BMT and MC), (P < 0.05) while the proportion of CD8 + T-cells was higher in MC-BMT without
International Nuclear Information System (INIS)
Kozak, Kevin R.; Hamidi, Maryam; Manning, Matthew; Moody, John S.
2012-01-01
Purpose: This study examines the management and outcomes of muscle-invasive bladder cancer in the United States. Methods and Materials: Patients with muscle-invasive bladder cancer diagnosed between 1988 and 2006 were identified in the Surveillance, Epidemiology, and End Results (SEER) database. Patients were classified according to three mutually exclusive treatment categories based on the primary initial treatment: no local management, radiotherapy, or surgery. Overall survival was assessed with Kaplan-Meier analysis and Cox models based on multiple factors including treatment utilization patterns. Results: The study population consisted of 26,851 patients. Age, sex, race, tumor grade, histology, and geographic location were associated with differences in treatment (all p < 0.01). Patients receiving definitive radiotherapy tended to be older and have less differentiated tumors than patients undergoing surgery (RT, median age 78 years old and 90.6% grade 3/4 tumors; surgery, median age 71 years old and 77.1% grade 3/4 tumors). No large shifts in treatment were seen over time, with most patients managed with surgical resection (86.3% for overall study population). Significant survival differences were observed according to initial treatment: median survival, 14 months with no definitive local treatment; 17 months with radiotherapy; and 43 months for surgery. On multivariate analysis, differences in local utilization rates of definitive radiotherapy did not demonstrate a significant effect on overall survival (hazard ratio, 1.002; 95% confidence interval, 0.999–1.005). Conclusions: Multiple factors influence the initial treatment strategy for muscle-invasive bladder cancer, but definitive radiotherapy continues to be used infrequently. Although patients who undergo surgery fare better, a multivariable model that accounted for patient and tumor characteristics found no survival detriment to the utilization of definitive radiotherapy. These results support continued
International Nuclear Information System (INIS)
Eida, Koichiro
1986-01-01
So far there is still considerable disagreement as to the evaluation of the pre- and postoperative irradiation effects on the survival rate of the patients with esophageal carcinoma. From April 1973 to December 1983, 138 cases of thoracic esophageal carcinoma were surgically operated upon at our Department; 68 cases were irradiated and 70 cases were not irradiated prior to the surgical operation. Followup study was done and its result has been reported in this communication. A few cases treated by pre-operative irradiation survived longer than the expected longevity in spite of their low curative operation rates. Prognosis was better in the cases with well differentiated squamous cell carcinoma, when marked or good responses to pre-operative irradiation with the calculated total dose of 30 Gy were recorded. There were differences in responsibility in the various histological types of esophageal carcinomas; good response in the group of well differentiated squamous carcinoma, less marked response in the groups of moderately and poorly differentiated squamous carcinomas, minor response in the types of undifferentiated and unclassifed carcinomas. From our observation it seems reasonable to say that prognosis of the patients with pre- and postoperative irradiation was better than that of those who received postoperative irradiation only. (author)
Hoseinifar, Seyed Hossein; Zare, Parviz; Kolangi Miandare, Hamed
2015-01-01
The present study investigates the effects of different routes of inulin administration as prebiotic on gut microbiota and survival rate of Indian white shrimp post-larvae. Four hundred and fifty Indian white shrimp post-larvae (PL1) were stocked in nine tanks. The tanks were assigned into three treatments: feeding with inulin-treated (110 mg L(-1)) Artemia nauplii (I-T), feeding with inulin-enriched (110 mg L(-1)) Artemia nauplii (I-E) and control which repeated triplicates. Feeding trial was performed until PL11 stage and then gut microbiota was studied using culture based method. Also, survival rate was calculated at the end of feeding trial. Our results showed that feeding on inulin enriched or treated Artemia nauplii had no significant effect on total viable culturable autochthonous bacteria and Vibrio spp. levels of the gut microbiota (p > 0.05). However, a remarkable increase of lactic acid bacteria levels (LAB) was observed in I-E treatment (p shrimp post-larvae (p shrimp but determination the mode of action of prebiotic on various aspects of shrimp larviculture merit further research.
Madeddu, M; Mosca, F; Abdel Sayed, A; Zaniboni, L; Mangiagalli, M G; Colombo, E; Cerolini, S
2016-08-01
The aim of the present trial was to study the effect of different freezing rates on the survival of cryopreserved rooster semen packaged in straws. Slow and fast freezing rates were obtained keeping straws at different distances in the vapor above the surface of the nitrogen during freezing. Adult Lohmann roosters (n=27) were used. Two experiments were conducted. In Experiment 1, semen was packaged in straws and frozen comparing the distances of 1, 3 and 5cm in nitrogen vapor above the surface of the liquid nitrogen. In Experiment 2, the distances of 3, 7 and 10cm above the surfaces of the liquid nitrogen were compared. Sperm viability, motility and progressive motility and the kinetic variables were assessed in fresh and cryopreserved semen samples. The recovery rates after freezing/thawing were also calculated. In Experiment 1, there were no significant differences among treatments for all semen quality variables. In Experiment 2, the percentage of viable (46%) and motile (22%) sperm in cryopreserved semen was greater when semen was placed 3cm compared with 7 and 10cm in the vapor above the surface of the liquid nitrogen. The recovery rate of progressive motile sperm after thawing was also greater when semen was stored 3cm in the vapor above the surface of the liquid nitrogen. More rapid freezing rates are required to improve the survival of rooster sperm after cryopreservation and a range of distances from 1 to 5cm in nitrogen vapor above the surface of the liquid nitrogen is recommended for optimal sperm viability. Copyright © 2016 Elsevier B.V. All rights reserved.
Directory of Open Access Journals (Sweden)
Schreiber, E. A.
2004-06-01
Full Text Available Annual survival and dispersal rates of adult and juvenile red-tailed tropicbirds were examined in connection with exposure to heavy metals. From 1990-2000 the incineration of a U.S. stockpile of chemical weapons stored at Johnston Atoll exposed nesting tropicbirds to increased levels of human disturbance, smoke stack emissions and potential leaks. Using a multi-state mark-recapture modeling approach, birds nesting in this site (downwind of the plant were compared to those nesting in a reference site (upwind of the plant with less human disturbance, no exposure to smoke stack emissions or other potential incineration emissions. We did not find any difference in survival of adults or juveniles when comparing the two sites. Adult breeding dispersal rates did not differ between the sites but we did find differences in the age-specific natal dispersal rates. Birds fledged from downwind areas were less likely to return to their natal area to nest and more likely to immigrate to the upwind area than vice-versa. This asymmetry in emigration rates is believed to be due to differing vegetation densities and has implications for vegetation management in relation to tropicbird nest success and population size.
Direct quantum mechanical calculation of the F + H{sub 2} {yields} HF + H thermal rate constant
Energy Technology Data Exchange (ETDEWEB)
Moix, Marc [Computer Simulation and Modeling (COSMO) Lab, Parc Cientific de Barcelona, Josep Samitier 5, 08028 Barcelona (Spain); Institut de Quimica Teorica i Computacional de la UB (IQTCUB), Universitat de Barcelona (Spain); Huarte-Larranaga, Fermin [Computer Simulation and Modeling (COSMO) Lab, Parc Cientific de Barcelona, Josep Samitier 5, 08028 Barcelona (Spain); Institut de Quimica Teorica i Computacional de la UB (IQTCUB), Universitat de Barcelona (Spain)], E-mail: fhuarte@pcb.ub.es
2008-07-03
Accurate full-dimensional quantum mechanical thermal rate constant values have been calculated for the F+H{sub 2}{yields}HF+H reaction on the Stark-Werner ab initio potential energy surface. These calculations are based on a flux correlation functions and employ a rigorous statistical sampling scheme to account for the overall rotation and the MCTDH scheme for the wave packet propagation. Our results shed some light on discrepancies on the thermal rate found for previous flux correlation based calculations with respect to accurate reactive scattering results. The resonance pattern of the all-J cumulative reaction probability is analyzed in terms of the partial wave contributions.
Effects of high dose rate gamma radiation on survival and reproduction of Biomphalaria glabrata
International Nuclear Information System (INIS)
Cantinha, Rebeca S.; Nakano, Eliana; Silva, Luanna R.S.
2009-01-01
Ionizing radiations are known as mutagenic agents, causing lethality and infertility. This characteristic has motivated its application on animal biological control. In this context, the freshwater snail Biomphalaria glabrata can be considered an excellent experimental model to study effects of ionizing radiations on lethality and reproduction. This work was designed to evaluate effects of 60 Co gamma radiation at high dose rate (10.04 kGy/h) on B. glabrata. For this purpose, adult snails were selected and exposed to doses ranging from 20 to 100 Gy, with 10 Gy intervals; one group was kept as control. There was not effect of dose rate in the lethality of gamma radiation; the value of 64,3 Gy of LD 50 obtained in our study was similar to that obtained by other authors with low dose rates. Nevertheless, our data suggest that there was a dose rate effect in the reproduction. On all dose levels, radiation improved the production of embryos for all exposed individuals. However, viability indexes were below 6% and, even 65 days after irradiation, fertility was not recovered. These results are not in agreement with other studies using low dose rates. Lethality was obtained in all groups irradiated, and the highest doses presented percentiles of dead animals above 50%. The results demonstrated that doses of 20 and 30 Gy were ideal for population control of B. glabrata. Further studies are needed; nevertheless, this research evidenced great potential of high dose rate gamma radiation on B. glabrata reproductive control. (author)
Effects of high dose rate gamma radiation on survival and reproduction of Biomphalaria glabrata
Energy Technology Data Exchange (ETDEWEB)
Cantinha, Rebeca S.; Nakano, Eliana [Instituto Butantan, Sao Paulo, SP (Brazil). Lab. de Parasitologia], e-mail: rebecanuclear@gmail.com, e-mail: eliananakano@butantan.gov.br; Borrely, Sueli I. [Instituto de Pesquisas Energeticas e Nucleares (IPEN-CNEN/SP), Sao Paulo, SP (Brazil). Centro de Tecnologia das Radiacoes], e-mail: sborrely@ipen.br; Amaral, Ademir; Melo, Ana M.M.A. [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Dept. de Energia Nuclear. Grupo de Estudos em Radioprotecao e Radioecologia (GERAR)], e-mail: amaral@ufpe.br; Silva, Luanna R.S. [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Dept. de Biofisica e Radiobiologia. Lab. de Radiobiologia], e-mail: amdemelo@hotmail.com, e-mail: luannaribeiro_lua@hotmail.com
2009-07-01
Ionizing radiations are known as mutagenic agents, causing lethality and infertility. This characteristic has motivated its application on animal biological control. In this context, the freshwater snail Biomphalaria glabrata can be considered an excellent experimental model to study effects of ionizing radiations on lethality and reproduction. This work was designed to evaluate effects of {sup 60}Co gamma radiation at high dose rate (10.04 kGy/h) on B. glabrata. For this purpose, adult snails were selected and exposed to doses ranging from 20 to 100 Gy, with 10 Gy intervals; one group was kept as control. There was not effect of dose rate in the lethality of gamma radiation; the value of 64,3 Gy of LD{sub 50} obtained in our study was similar to that obtained by other authors with low dose rates. Nevertheless, our data suggest that there was a dose rate effect in the reproduction. On all dose levels, radiation improved the production of embryos for all exposed individuals. However, viability indexes were below 6% and, even 65 days after irradiation, fertility was not recovered. These results are not in agreement with other studies using low dose rates. Lethality was obtained in all groups irradiated, and the highest doses presented percentiles of dead animals above 50%. The results demonstrated that doses of 20 and 30 Gy were ideal for population control of B. glabrata. Further studies are needed; nevertheless, this research evidenced great potential of high dose rate gamma radiation on B. glabrata reproductive control. (author)
MO-D-213-07: RadShield: Semi- Automated Calculation of Air Kerma Rate and Barrier Thickness
International Nuclear Information System (INIS)
DeLorenzo, M; Wu, D; Rutel, I; Yang, K
2015-01-01
Purpose: To develop the first Java-based semi-automated calculation program intended to aid professional radiation shielding design. Air-kerma rate and barrier thickness calculations are performed by implementing NCRP Report 147 formalism into a Graphical User Interface (GUI). The ultimate aim of this newly created software package is to reduce errors and improve radiographic and fluoroscopic room designs over manual approaches. Methods: Floor plans are first imported as images into the RadShield software program. These plans serve as templates for drawing barriers, occupied regions and x-ray tube locations. We have implemented sub-GUIs that allow the specification in regions and equipment for occupancy factors, design goals, number of patients, primary beam directions, source-to-patient distances and workload distributions. Once the user enters the above parameters, the program automatically calculates air-kerma rate at sampled points beyond all barriers. For each sample point, a corresponding minimum barrier thickness is calculated to meet the design goal. RadShield allows control over preshielding, sample point location and material types. Results: A functional GUI package was developed and tested. Examination of sample walls and source distributions yields a maximum percent difference of less than 0.1% between hand-calculated air-kerma rates and RadShield. Conclusion: The initial results demonstrated that RadShield calculates air-kerma rates and required barrier thicknesses with reliable accuracy and can be used to make radiation shielding design more efficient and accurate. This newly developed approach differs from conventional calculation methods in that it finds air-kerma rates and thickness requirements for many points outside the barriers, stores the information and selects the largest value needed to comply with NCRP Report 147 design goals. Floor plans, parameters, designs and reports can be saved and accessed later for modification and recalculation
MO-D-213-07: RadShield: Semi- Automated Calculation of Air Kerma Rate and Barrier Thickness
Energy Technology Data Exchange (ETDEWEB)
DeLorenzo, M [Oklahoma University Health Sciences Center, Oklahoma City, OK (United States); Wu, D [University of Oklahoma Health Sciences Center, Oklahoma City, Ok (United States); Rutel, I [University of Oklahoma Health Science Center, Oklahoma City, OK (United States); Yang, K [Massachusetts General Hospital, Boston, MA (United States)
2015-06-15
Purpose: To develop the first Java-based semi-automated calculation program intended to aid professional radiation shielding design. Air-kerma rate and barrier thickness calculations are performed by implementing NCRP Report 147 formalism into a Graphical User Interface (GUI). The ultimate aim of this newly created software package is to reduce errors and improve radiographic and fluoroscopic room designs over manual approaches. Methods: Floor plans are first imported as images into the RadShield software program. These plans serve as templates for drawing barriers, occupied regions and x-ray tube locations. We have implemented sub-GUIs that allow the specification in regions and equipment for occupancy factors, design goals, number of patients, primary beam directions, source-to-patient distances and workload distributions. Once the user enters the above parameters, the program automatically calculates air-kerma rate at sampled points beyond all barriers. For each sample point, a corresponding minimum barrier thickness is calculated to meet the design goal. RadShield allows control over preshielding, sample point location and material types. Results: A functional GUI package was developed and tested. Examination of sample walls and source distributions yields a maximum percent difference of less than 0.1% between hand-calculated air-kerma rates and RadShield. Conclusion: The initial results demonstrated that RadShield calculates air-kerma rates and required barrier thicknesses with reliable accuracy and can be used to make radiation shielding design more efficient and accurate. This newly developed approach differs from conventional calculation methods in that it finds air-kerma rates and thickness requirements for many points outside the barriers, stores the information and selects the largest value needed to comply with NCRP Report 147 design goals. Floor plans, parameters, designs and reports can be saved and accessed later for modification and recalculation
Hot-electron-mediated desorption rates calculated from excited-state potential energy surfaces
DEFF Research Database (Denmark)
Olsen, Thomas; Gavnholt, Jeppe; Schiøtz, Jakob
2009-01-01
We present a model for desorption induced by (multiple) electronic transitions [DIET (DIMET)] based on potential energy surfaces calculated with the delta self-consistent field extension of density-functional theory. We calculate potential energy surfaces of CO and NO molecules adsorbed on variou...
International Nuclear Information System (INIS)
Vergnaud, T.; Bourdet, L.; Gonnord, J.; Nimal, J.C.; Champion, G.
1984-01-01
Conception of a reactor building requires large openings in the primary concrete shield for a postulated loss-of-coolant accident. Through these openings neutrons escape and produce dose rates in several parts of the reactor building. Some calculations using ANISN, DOT and essentially TRIPOLI-2 codes allow to compute the neutron dose rates at several places such as reactor containment operating floor and containment annulus. Some complementary shields are provided and the instrumentations are placed in area where the dose rate is lower. Comparisons are presented between measurements and calculations
Survival of tumor bearing mice by sequencing of low dose rate (LDR) neutron and photon radiation
International Nuclear Information System (INIS)
Onomura, C.I.; Feola, J.M.; Maruyama, Y.
1984-01-01
Cf-252 neutron radiation (NT) has been shown to be effective therapy for bulky, hypoxic human tumor and to produce consistent rapid clearance and 5 year cures. NT has been found to be more or less effective depending upon the schedule in which it is used and upon mixing with photon radiation. In an effort to study this scheduling and photon effect, LSA tumor was irradiated in vivo in a hypoxic, advanced state, in different schedules in combination of NT with Co-60 photons. The LSA lymphoma of C57BL/ym mice represents an accurate system to assess dose-response of tumor cells in vivo. Mean survival time was used as endpoint. A high RBE for LDR Cf-252 NT was observed with a RBE(n) of -- 5.0. The effect was not greatly sensitive to sequence in which photons were used. Comparison studies were also tested relative to LDR Cs-137 photon radiation. The results support the high efficacy of LDR NT for destruction of hypoxic tumor in vivo
Directory of Open Access Journals (Sweden)
Naoko Isomura
Full Text Available Natural hybridization of corals in the Indo-Pacific has been considered rather rare. However, field studies have observed many corals with intermediate interspecific or unusual morphologies. Given that the existence of F1 hybrids with intermediate interspecific morphologies has been proven in the Caribbean, hybrids may also inhabit the Indo-Pacific and occur more frequently than expected. In this study, we focused on two morphologically different species, Acropora florida and A. intermedia, and performed crossing experiments at Akajima Island, Japan. Results showed that these species could hybridize in both directions via eggs and sperm, but that fertilization rates significantly differed according to which species provided eggs. These results are similar to those reported from the Caribbean. Although all embryos developed normally to the planular larval stage, the developmental processes of some hybrid embryos were delayed by approximately 1 h compared with conspecific embryos, suggesting that fertilization occurred 1 h later in interspecific crosses than in intraspecific crosses. More successful hybridization could occur under conditions with low numbers of conspecific colonies. Additionally, a comparison of survival rates between hybrid and intraspecific larvae revealed that intra- and interspecific larvae produced from eggs of A. florida survived for significantly longer than those produced from eggs of A. intermedia. Considering these data, under specific conditions, hybrids can be expected to be produced and survive in nature in the Pacific. Furthermore, we identified one colony with intermediate morphology between A. florida and A. intermedia in the field. This colony was fertilized only by eggs of A. florida, with high fertilization rates, suggesting that this colony would be a hybrid of these two species and might be backcrossed.
Survival rates and lifetime reproduction of breeding male Cooper’s Hawks in Wisconsin, 1980-2005
Rosenfield, Robert N.; Bielefeldt, John; Rosenfield, Laura J.; Booms, Travis L.; Bozek, Michael A.
2009-01-01
There are few published data on annual survival and no reports of lifetime reproduction for breeding Cooper's Hawks (Accipiter cooperii). Breeding males (n = 105) in central and southeastern Wisconsin had an annual mortality rate of 19%, or a survival rate of 81% for birds ≤10 years of age. We did not detect significant differences in mortality rates between urban and rural habitats, nor between the earlier 13 years and later 13 years of this study. Male Cooper's Hawks produced from zero to 32 nestlings during their lifetimes. Body mass or size appeared unrelated to annual survivorship and lifetime reproduction, although lifetime reproduction was correlated strongly with longevity of breeding males. Fifteen of 66 males (23%) produced most (53%) of the nestlings. Our studies occurred in an area where breeding populations may be increasing with some of the highest reported productivity indices and nesting densities for this species. Habitat used for nesting on our Wisconsin study areas may be less important for survivorship and lifetime reproduction than acquisition of a nesting area in which a male will breed throughout his life.
El-Reshaid, Wael; Al-Disawy, Hanan; Nassef, Hossameldeen; Alhelaly, Usama
2016-09-01
Peritonitis is a common complication in patients undergoing continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD). In this retrospective study, peritonitis rates and patient survival of 180 patients on CAPD and 128 patients on APD were compared in the period from January 2005 to December 2014 at Al-Nafisi Center in Kuwait. All patients had prophylactic topical mupirocin at catheter exit site. Patients on CAPD had twin bag system with Y transfer set. The peritonitis rates were 1 in 29 months in CAPD and 1 in 38 months in APD (p peritonitis free patients over 10-year period in CAPD and APD were 49 and 60%, respectively (p peritonitis was 10.25 ± 3.1 months in CAPD compared to 16.1 ± 4 months in APD (p peritonitis was 13.1 ± 1 and 14 ± 1.4 months respectively (p = 0.3) whereas in peritonitis free patients it was 15 ± 1.4 months in CAPD and 23 ± 3.1 months in APD (p = 0.025). APD had lower incidence rate of peritonitis than CAPD. Patient survival was better in APD than CAPD in peritonitis free patients but was similar in patients who had peritonitis.
Daily survival rates for nests of Black Skimmers from a core breeding area of the Southeastern USA
Brooks, Gillian L.; Sanders, Felicia J.; Gerard, Patrick D.; Jodice, Patrick G.R.
2014-01-01
Little is known about the reproductive success of Black Skimmers (Rynchops niger) throughout the southeastern USA where availability of undisturbed beaches for nesting is limited. Daily survival rates (DSR) of nests were examined at three nesting sites in Cape Romain National Wildlife Refuge (CRNWR), South Carolina, USA, 2009–2010. The percent of successful nests (n = 346 nests) ranged from 42–69% among colony sites when data were pooled across both years. The DSR of nests was primarily related to colony site, predation risk, height of high tide, and clutch size. Predation and overwash were the principal causes of identifiable nest loss, each accounting for ∼33% of nest failures during the two study years. Because of the challenges of resighting skimmer chicks, we were not able to measure chick survival effectively and therefore accurate measures of productivity remain elusive. High variability in nest success among sites within close proximity to each other (stressors such as tropical storms or food availability. Although time-intensive techniques to control predators do exist, management options to limit flooding and overwash are far more limited. Conservation of Black Skimmers in the southeastern USA would benefit from coordinated, multi-state efforts to measure nest and chick survival.
Directory of Open Access Journals (Sweden)
Marlen Martinez-Gutierrez
Full Text Available BACKGROUND: It has been reported that treatment of DENV-infected cultures with Lovastatin (LOV, can affect viral assembly. The objective of this study was to evaluate the effect of LOV on the survival rate and viremia levels of DENV-2-infected AG129 mice. METHODOLOGY/PRINCIPAL FINDINGS: Mice were inoculated with 1 × 10(6 plaque-forming units (PFU/ml of DENV-2 and treated with LOV (200 mg/kg/day. Pre-treatment with one or three doses of LOV increased the survival rate compared to untreated mice (7.3 and 7.1 days, respectively, compared to 4.8 days. Viremia levels also decreased by 21.8% compared to untreated mice, but only in the group administered three doses prior to inoculation. When LOV was administered after viral inoculation, the survival rate increased (7.3 days in the group treated at 24 hpi, 6.8 days in the group treated at 48 hpi and 6.5 days in the group treated with two doses compared to the untreated group (4.8 days. Interestingly, the serum viral titer increased by 24.6% in mice treated at 48 hpi with a single dose of LOV and by 21.7% in mice treated with two doses (at 24 and 48 hpi of LOV compared to untreated mice. Finally histopathological changes in the liver and spleen in infected and untreated mice included massive extramedullary erythropoiesis foci and inflammatory filtration, and these characteristics were decreased or absent in LOV-treated mice. CONCLUSIONS/SIGNIFICANCE: Our results suggest that the effect of LOV on viremia depends on the timing of treatment and on the number of doses administered. We observed a significant increase in the survival rate in both schemes due to a delay in the progression of the disease. However, the results obtained in the post-treatment scheme must be handled carefully because this treatment scheme increases viremia and we do not know how this increase could affect disease progression in humans.
38 CFR 3.23 - Improved pension rates-Veterans and surviving spouses.
2010-07-01
... and World War I veterans. The applicable maximum annual rate payable to a Mexican border period or World War I veteran under this section shall be increased by the amount specified in 38 U.S.C. 1521(g...(d)) (3) Veterans who are housebound. (Authority: 38 U.S.C. 1521(e)) (4) Two veterans married to one...
Survival, fidelity, and recovery rates of white-winged doves in Texas
Collier, Bret A.; Kremer, Shelly R.; Mason, Corey D.; Peterson, Markus J.; Calhoun, Kirby W.
2012-01-01
the last 30 years. Because >85% of white-winged dove harvest in the United States (approx. 1.3 million annually) now occurs in Texas, information on vital rates of expanding white-winged dove populations is necessary for informed management. We used band
Growth rates and post-release survival of captive neonate timber rattlesnakes Crotalus horridus
Richard N. Conner; D. Craig Rudolph; Daniel Saenz; Richard R. Schaefer; Shirley J. Burgdorf
2003-01-01
The need for conservation and management of rare species is becoming increasingly important as wildlife species and their habitat continue to decline. Translocation of wild captured adults to augment and reintroduce populations has been successfully used for some endangered avian species (see Carrie et al. 1999; Rudolph et al. 1992). In general, success rates for...
Effect of Formalin on the Hatching Rate of eggs and Survival of ...
African Journals Online (AJOL)
Michael Horsfall
1, and 1000 mgl-1 of formalin resulted in total egg mortality (0% hatching rate). In the definitive ... treatment of fish disease, particularly fungi, as in this study, where it effectively reduced fungi on eggs and larvae of ... salmon held for spawning).
Lung deposition of sub-micron aerosols calculated as a function of age and breathing rate
International Nuclear Information System (INIS)
James, A.C.
1978-01-01
Experimental measurements of lung deposition and especially of regional deposition, of aerosols in the sub-micron size range have been so few that it is worthwhile establishing a method of calculation. A computer routine has therefore been developed to calculate aerosol deposition in successive bronchial and bronchiolar generations of the Weibel 'A' model of human lung for the sub-micron size range where deposition occurs solely by diffusion. This model can be scaled to represent lungs at various ages and vital capacities. Some calculated results are presented here and compared with measurements of lung deposition made under carefully controlled conditions in humans. (author)
Opfermann, Krisha J; Wahlquist, Amy; Watkins, John; Kohler, Matthew; Jenrette, Joseph
2012-03-01
To evaluate whether Point A asymmetry in low dose-rate (LDR) brachytherapy is associated with local control (LC), disease-free survival (DFS) and/or overall survival (OS). A retrospective analysis of disease control and survival outcomes was conducted for patients who underwent LDR brachytherapy for advanced cervical cancer. Institutional protocol entailed concurrent chemotherapy and whole pelvis radiotherapy (WPRT) over 5 weeks, followed by placement of Fletcher-Suit tandem and colpostat applicators at weeks 6 and 8. Objective Point A doses, 80-85 Gy, were accomplished by placement of Cesium-137 (Cs-137) sources. Cox proportional hazards regression models were used to assess associations between disease control and survival endpoints with variables of interest. The records of 50 patients with FIGO stage IB1-IVA cervical cancer undergoing LDR brachytherapy at our institution were identified. Thirty of these patients had asymmetry > 2.5%, and 11 patients had asymmetry > 5%. At a median survivor follow-up of 20.25 months, 15 patients had experienced disease failure (including 5 cervical/vaginal apex only failures and 2 failures encompassing the local site). Right/left dose asymmetry at Point A was associated with statistically significantly inferior LC (p = 0.035) and inferior DFS (p = 0.011) for patients with mean Point A dose of > 80 Gy. Insufficient evidence existed to conclude an association with OS. LDR brachytherapy may be associated with clinically significant dose asymmetry. The present study demonstrates that patients with Point A asymmetry have a higher risk of failure for DFS and LC.
Interaction Cross Sections and Survival Rates for Proposed Solar System Member Planet Nine
Li, Gongjie; Adams, Fred C.
2016-05-01
Motivated by the report of a possible new planetary member of the solar system, this work calculates cross sections for interactions between passing stars and this proposed Planet Nine. Evidence for the new planet is provided by the orbital alignment of Kuiper belt objects, and other solar system properties, which suggest a Neptune-mass object on an eccentric orbit with a semimajor axis {a}9 ≈ 400-1500 au. With such a wide orbit, Planet Nine has a large interaction cross section and is susceptible to disruption by passing stars. Using a large ensemble of numerical simulations (several million) and Monte Carlo sampling, we calculate the cross sections for different classes of orbit-altering events: (A) scattering the planet into its proposed orbit from a smaller orbit, (B) ejecting it from the solar system from its current orbit, (C) capturing the planet from another system, and (D) capturing a free-floating planet. Results are presented for a range of orbital elements with planetary mass {m}9 = 10 M ⊕. Removing Planet Nine from the solar system is the most likely outcome. Specifically, we obtain ejection cross sections {σ }{int} ˜ 5 × 106 au2 (5 × 104 au2) for environments corresponding to the birth cluster (field). With these cross sections, Planet Nine is likely to be ejected if the Sun resides within its birth cluster longer than Δt ≳ 100 Myr. The probability of ejecting Planet Nine due to passing field stars is ≲3% over the age of the Sun. Probabilities for producing the inferred Planet Nine orbit are low (≲5%).
Ariyati, R. W.; Rejeki, S.; Bosma, R. H.
2018-02-01
Blue swimming crab is targeted by commercial fisheries because of the high economic value, good taste, and attractive colors. As a result, the stock is overexploited and fisherman catch market also juveniles. The most sustainable solution would be to stop fishing for commercial trade and to culture this crab from brood to market size. This study aimed to find the best feed and stocking density for the on-growing of crablets. In 20 tanks juvenile crabs with a carapace width±1 cm were stocked in three densities; 40, 60 and 80 crablets / m2, and fed ad-libitum twice a day with either trash fish or pellets of shrimp feed, for 8 weeks. The circular (ᴓ 1.6 m x 1 m) tanks with 1 m3 of water were aerated, and temperature, salinity, dissolved oxygen and pH recorded daily. In the end, growth and survival rates were determined. In general, feeding the crablets at a density of 40 m-2 gave the highest growth. For crablest fed with pellets, the density of 40 m-2 gave significantly better growth than 80 m-2. The crablets at a density 40 m-2 having a fish diet with the density 40 m-2 grew better than 60 and 80 m-2. There was no significant difference between fed used among different densities. The lower densities resulted in higher survival, either on crablets fed with pellets or fish. But, crablets fed the fish diet and cultured in the lowest density (40 m-2) had the highest survival rate.
International Nuclear Information System (INIS)
Abramova, N.V.
1978-01-01
The effect of the continuous monochromatic coherent laser radiation on the survival rate of Saccharomyces cerevisiae of strain 14 is studied. The effect of laser radiation is judged by the change in the survival rate of the yeast culture before and after the irradiation. The decrease of the number of the yeast cells in the initial moments of the irradiation was observed as a result of the laser irradiation. Then the rapid decrease of the number of cells with time changes into their constant number. It is established that the low-energy coherent radiation decreases the survival rate by 30-40%
Liu, Dapeng
2017-01-10
Reaction rate coefficients for the reaction of hydroxyl (OH) radicals with nine large branched alkanes (i.e., 2-methyl-3-ethyl-pentane, 2,3-dimethyl-pentane, 2,2,3-trimethylbutane, 2,2,3-trimethyl-pentane, 2,3,4-trimethyl-pentane, 3-ethyl-pentane, 2,2,3,4-tetramethyl-pentane, 2,2-dimethyl-3-ethyl-pentane, and 2,4-dimethyl-3-ethyl-pentane) are measured at high temperatures (900-1300 K) using a shock tube and narrow-line-width OH absorption diagnostic in the UV region. In addition, room-temperature measurements of six out of these nine rate coefficients are performed in a photolysis cell using high repetition laser-induced fluorescence of OH radicals. Our experimental results are combined with previous literature measurements to obtain three-parameter Arrhenius expressions valid over a wide temperature range (300-1300 K). The rate coefficients are analyzed using the next-nearest-neighbor (N-N-N) methodology to derive nine tertiary (T003, T012, T013, T022, T023, T111, T112, T113, and T122) site-specific rate coefficients for the abstraction of H atoms by OH radicals from branched alkanes. Derived Arrhenius expressions, valid over 950-1300 K, are given as (the subscripts denote the number of carbon atoms connected to the next-nearest-neighbor carbon): T003 = 1.80 × 10-10 exp(-2971 K/T) cm3 molecule-1 s-1; T012 = 9.36 × 10-11 exp(-3024 K/T) cm3 molecule-1 s-1; T013 = 4.40 × 10-10 exp(-4162 K/T) cm3 molecule-1 s-1; T022 = 1.47 × 10-10 exp(-3587 K/T) cm3 molecule-1 s-1; T023 = 6.06 × 10-11 exp(-3010 K/T) cm3 molecule-1 s-1; T111 = 3.98 × 10-11 exp(-1617 K/T) cm3 molecule-1 s-1; T112 = 9.08 × 10-12 exp(-3661 K/T) cm3 molecule-1 s-1; T113 = 6.74 × 10-9 exp(-7547 K/T) cm3 molecule-1 s-1; T122 = 3.47 × 10-11 exp(-1802 K/T) cm3 molecule-1 s-1.
DEFF Research Database (Denmark)
Vegge, Tejs
2004-01-01
The dissociation of molecular hydrogen on a Mgs0001d surface and the subsequent diffusion of atomic hydrogen into the magnesium substrate is investigated using Density Functional Theory (DFT) calculations and rate theory. The minimum energy path and corresponding transition states are located usi...... to be rate-limiting for the ab- and desorption of hydrogen, respectively. Zero-point energy contributions are found to be substantial for the diffusion of atomic hydrogen, but classical rates are still found to be within an order of magnitude at room temperature.......The dissociation of molecular hydrogen on a Mgs0001d surface and the subsequent diffusion of atomic hydrogen into the magnesium substrate is investigated using Density Functional Theory (DFT) calculations and rate theory. The minimum energy path and corresponding transition states are located using...
Directory of Open Access Journals (Sweden)
Muharijadi Atmomarsono
2015-06-01
Full Text Available Instead of culturing tiger shrimp that is frequently burdened by mass mortality, whiteleg shrimp (Litopenaeus vannamei is then considered as an alternative commodity in Indonesian brackishwater ponds. To prevent the whiteleg shrimp from diseases, different probiotic bacteria were tested in completely randomized design experiment using nine 250 m2 experimental ponds stocked with 10 PLs of whiteleg shrimp fry/m2. Three treatments were applied, namely A alternate use of probiotic bacteria RICA-1, RICA-2, RICA-3; B alternate use of probiotic bacteria RICA-4, RICA-5, RICA-3, and C control (without probiotic bacteria; each with three replications. After 11-week application, the results showed that the best survival rate of whiteleg shrimp was achieved by treatment B 98.83% and the best production was achieved by treatment A (23.52 kg/250 m2. However, there were no significant differences (P>0.05 among the three treatments tested for the shrimp survival rate. The whiteleg shrimp production in treatment A and B were signicantly better (P<0.05 than that in treatment C (control. These high shrimp production in treatment A and B were mainly caused by the capability of the applied probiotics in controlling some water quality variables and Vibrio numbers.
Directory of Open Access Journals (Sweden)
Hakan Kocoglu
2016-01-01
Full Text Available Purpose. In this study we tried to determine the association between body-mass index (BMI, survival rate, and the stage of tumor at the time of diagnosis in patients with gastric cancer. Methods. A total of 270 gastric cancer patients’ hospital records were retrospectively evaluated. Patients were grouped according to their BMI at the time of tumor diagnosis. Tumor stages at admission were compared according to their BMI values. Results. There were no differences in OS among BMI subgroups (p=0.230. The percent of patients with stage III tumor was significantly higher in nonobese while the percent of stage IV tumor was surprisingly higher in obese patients (p was 0.011 and 0.004, resp.. Percent of patients who did not have any surgical intervention was significantly lower in overweight and obese patients than normal and/or underweight patients. Conclusions. At the time of diagnosis, obese patients had significantly higher percent of stage IV tumor than nonobese patients. Despite of that, there were no differences in survival rates among BMI subgroups. Our study results are consistent with “obesity paradox” in gastric cancer patients. We also did not find any relationship between BMI and localization of gastric tumor.
Energy Technology Data Exchange (ETDEWEB)
Robinson, R C [Atlantic Nuclear Services Ltd. (Canada); Tran, F [Ontario Hydro, Pickering, ON (Canada). Pickering Generating Station
1996-12-31
A homogenization methodology for calculation of reactivity device incremental cross-sections has been developed using reaction rate conservation (RRC). A heterogeneous transport calculation of flux was utilised to produce the homogenized cross-sections for a finite difference two group diffusion code. The RRC cross-sections have been shown to improve significantly the prediction of reactivity worth for stainless steel adjuster rods installed in Pickering NGS reactors. (author). 10 refs., 3 tabs., 6 figs.
International Nuclear Information System (INIS)
Bondars, Kh.Ya.; Lapenas, A.A.
1981-01-01
We adapted or used on ES EhVM, operating under the control of OS ES, the currently most common algorithms for calculating neutron spectra from measured reaction rates. These programs, together with the neutron cross-section and spectrum libraries, are part of the computerized information system SAIPS. The present article descibes the basic mathematical concepts used in the algorithms of the SAIPS calculation programs
Dose-rate models for human survival after exposure to ionizing radiation
International Nuclear Information System (INIS)
Jones, T.D.; Morris, M.D.; Young, R.W.
1987-01-01
This paper reviews new estimates of the LD 50 in man by Mole and by Rotblat, the biological processes contributing to hematologic death, the collection of animal experiments dealing with hematologic death, and the use of regression analysis to make new estimates of human mortality based on all relevant animal studies. Regression analysis of animal mortality data has shown that mortality is dependent strongly on dose rate, species, body weight, and time interval over which the exposure is delivered. The model has predicted human LD 50 s of 194, 250, 310, and 360 rad to marrow when the exposure time is a minute, an hour, a day, and a week, respectively
Dose-rate models for human survival after exposure to ionizing radiation
International Nuclear Information System (INIS)
Jones, T.D.; Morris, M.D.; Young, R.W.
1986-01-01
This paper reviews new estimates of the L 50 in man by Mole and by Rotblat, the biological processes contributing to hematologic death, the collection of animal experiments dealing with hematologic death, and the use of regression analysis to make new estimates of human mortality based on all relevant animal studies. Regression analysis of animal mortality data has shown that mortality is dependent strongly on dose rate, species, body weight, and time interval over which the exposure is delivered. The model has predicted human LD 50 s of 194, 250, 310, and 360 rad to marrow when the exposure time is a minute, an hour, a day, and a week, respectively
Calculation of the external dose rate in the spent fuel pool for the case to use compact racks
International Nuclear Information System (INIS)
Passos, E.M. dos; Alves, A.S.M.
1988-01-01
The possible introduction of compact racks in the spent fuel pool of the Angra 1 Nuclear Power Plant largely inreases its storage capacity, but originates an increase of the gamma radiation sources. The precise evaluation of the effects of the adoption of this option on the external gamma dose rates and also on the thickness of the concrete shielding requires the utilization of sofisticated computer codes (QAD, ANISN), which allow the calculation of the gamma dose rates through thick shielding walls. This paper describes the utilized methodology for the calculation of the modified pool shieldings, showing the obtained results for the Angra 1 NPP case. The gamma dose rate was calculated with the point Kernel model, first analytically, and later through utilization of the tridimensional multigroup QAD computer code. (author) [pt
International Nuclear Information System (INIS)
Riahi, R.; Ben Lakhdar, Z.; Teulet, Ph.; Gleizes, A.
2006-01-01
The weighted total cross-sections (WTCS) theory is used to calculate electron impact excitation, ionization and dissociation cross-sections and rate coefficients of OH, H 2 , OH + , H 2 + , OH - and H 2 - diatomic molecules in the temperature range 1500-15000 K. Calculations are performed for H 2 (X, B, C), OH(X, A, B), H 2 + (X), OH + (X, a, A, b, c), H 2 - (X) and OH - (X) electronic states for which Dunham coefficients are available. Rate coefficients are calculated from WTCS assuming Maxwellian energy distribution functions for electrons and heavy particles. One and 2 temperatures (θ e and θ g respectively for electron and heavy particles kinetic temperatures) results are presented and fitting parameters (a, b and c) are given for each reaction rate coefficient: k(θ) a(θ b )exp(-c/θ). (authors)
Rezaei Hachesu, Peyman; Moftian, Nazila; Dehghani, Mahsa; Samad Soltani, Taha
2017-06-25
Background: Data mining, a new concept introduced in the mid-1990s, can help researchers to gain new, profound insights and facilitate access to unanticipated knowledge sources in biomedical datasets. Many issues in the medical field are concerned with the diagnosis of diseases based on tests conducted on individuals at risk. Early diagnosis and treatment can provide a better outcome regarding the survival of lung cancer patients. Researchers can use data mining techniques to create effective diagnostic models. The aim of this study was to evaluate patterns existing in risk factor data of for mortality one year after thoracic surgery for lung cancer. Methods: The dataset used in this study contained 470 records and 17 features. First, the most important variables involved in the incidence of lung cancer were extracted using knowledge discovery and datamining algorithms such as naive Bayes, maximum expectation and then, using a regression analysis algorithm, a questionnaire was developed to predict the risk of death one year after lung surgery. Outliers in the data were excluded and reported using the clustering algorithm. Finally, a calculator was designed to estimate the risk for one-year post-operative mortality based on a scorecard algorithm. Results: The results revealed the most important factor involved in increased mortality to be large tumor size. Roles for type II diabetes and preoperative dyspnea in lower survival were also identified. The greatest commonality in classification of patients was Forced expiratory volume in first second (FEV1), based on levels of which patients could be classified into different categories. Conclusion: Development of a questionnaire based on calculations to diagnose disease can be used to identify and fill knowledge gaps in clinical practice guidelines. Creative Commons Attribution License
Survival of tumor cells after proton irradiation with ultra-high dose rates
International Nuclear Information System (INIS)
Auer, Susanne; Hable, Volker; Greubel, Christoph; Drexler, Guido A; Schmid, Thomas E; Belka, Claus; Dollinger, Günther; Friedl, Anna A
2011-01-01
Laser acceleration of protons and heavy ions may in the future be used in radiation therapy. Laser-driven particle beams are pulsed and ultra high dose rates of >10 9 Gy s -1 may be achieved. Here we compare the radiobiological effects of pulsed and continuous proton beams. The ion microbeam SNAKE at the Munich tandem accelerator was used to directly compare a pulsed and a continuous 20 MeV proton beam, which delivered a dose of 3 Gy to a HeLa cell monolayer within < 1 ns or 100 ms, respectively. Investigated endpoints were G2 phase cell cycle arrest, apoptosis, and colony formation. At 10 h after pulsed irradiation, the fraction of G2 cells was significantly lower than after irradiation with the continuous beam, while all other endpoints including colony formation were not significantly different. We determined the relative biological effectiveness (RBE) for pulsed and continuous proton beams relative to x-irradiation as 0.91 ± 0.26 and 0.86 ± 0.33 (mean and SD), respectively. At the dose rates investigated here, which are expected to correspond to those in radiation therapy using laser-driven particles, the RBE of the pulsed and the (conventional) continuous irradiation mode do not differ significantly
Dose-rate models for human survival after exposure to ionizing radiation
Energy Technology Data Exchange (ETDEWEB)
Jones, T.D.; Morris, M.D.; Young, R.W.
1986-01-01
This paper reviews new estimates of the L/sub 50/ in man by Mole and by Rotblat, the biological processes contributing to hematologic death, the collection of animal experiments dealing with hematologic death, and the use of regression analysis to make new estimates of human mortality based on all relevant animal studies. Regression analysis of animal mortality data has shown that mortality is dependent strongly on dose rate, species, body weight, and time interval over which the exposure is delivered. The model has predicted human LD/sub 50/s of 194, 250, 310, and 360 rad to marrow when the exposure time is a minute, an hour, a day, and a week, respectively.
Point kernel technique for calculating dose rates due to cobalt-60 hot particles
International Nuclear Information System (INIS)
Thornhill, M.J.; McCarthy, J.T.; Morrissette, R.R.; Leach, B.N.
1989-01-01
This paper reports on a computer code called BETA that has been developed by health physicists at the Vermont Yankee Nuclear Power Station which accounts for the mass and size of hot particles of Cobalt-60, and therefore corrects the Loevinger-based dose calculation for self-absorption
42 CFR 419.32 - Calculation of prospective payment rates for hospital outpatient services.
2010-10-01
... outpatient services furnished in 1999 would have equaled the base expenditure target calculated in § 419.30... inpatient market basket percentage increase applicable under section 1886(b)(3)(B)(iii) of the Act reduced... 1, 2001 and before April 1, 2001, by the hospital inpatient market basket percentage increase...
Data and software for calculating neutron spectra from measured reaction rates
International Nuclear Information System (INIS)
Berzonis, M.A.; Bonbars, Kh.Ya.
1981-01-01
The information system SAIPS is presented, which allows the automated calculation of neutron spectra and the use of cross section libraries on EC type computers. The following programmes can be applied: SAND II, WINDOWS, CRYSTAL BALL, RFSP JUEL, etc. The system includes both cross section libraries established by means of the code mentioned and libraries recommended by several laboratories. (author)
Window Energy Rating System and Calculation of Energy Performance of Windows
DEFF Research Database (Denmark)
Laustsen, Jacob Birck; Svendsen, Svend
The goal of reducing the energy consumption in buildings is the background for the introduction of an energy rating system of fenestration products in Denmark. The energy rating system requires that producers declare, among other things, the heat loss coefficient, U, and the total solar energy...... development, e.g. when the resulting effects of a reduced frame area are evaluated....
NCLB Implementation Report: State Approaches for Calculating High School Graduation Rates.
Swanson, Christopher B.
This review investigated the state accountability Workbooks provisionally approved and publicly reported by the U.S. Department of Education (DOE) as of June 2003. These documents were obtained from the DOE Web site. This report examines state definitions of high school graduation rates and strategies for constructing graduation rate indicators. A…
Directory of Open Access Journals (Sweden)
Muhammad Junaidi
2015-02-01
Full Text Available ABSTRACT The development of lobster farming in floating net cage in Ekas Bay caused an environmental degradation such as decrease water quality due to some aquaculture wastes. The purposes of this study were to determine the status of water quality and their effect on growth and survival rate of lobster reared in floating net cages (FNC in the Ekas Bay, West Nusa Tenggara Province. Water sample collection and handling referred to the APHA (1992. Analyses of water quality data were conducted using Principal Component Analysis. Determination of the water quality status of Ekas Bay was performed with STORET system. Multivariate analyses were used to determine the relationship between water quality, growth, and survival rate of lobster reared in FNC. Results showed that Ekas Bay water quality status was categorized in class C (medium contaminated, which exceeded some quality standard parameters such as ammonia (0.3 mg/l, nitrate (0.008 mg/l, and phosphate (0.015 mg/l. During lobster farming activities feeding with trash fish for 270 days, we obtained daily growth rate of 0.74% (lower than normal growth rate of 0.86%, survival rate of 66% (lower than normal survival rate of 86.7%, and feed conversion ratio of 11.15. Ammonia was found as a dominant factor reducing growth and survival rate of lobster reared in FNC. Keywords: water quality, lobsters, growth, survival, Ekas Bay
International Nuclear Information System (INIS)
Kokoouline, V.; Richardson, W.
2014-01-01
Uncertainties in theoretical calculations may include: • Systematic uncertainty: Due to applicability limits of the chosen model. • Random: Within a model, uncertainties of model parameters result in uncertainties of final results (such as cross sections). • If uncertainties of experimental and theoretical data are known, for the purpose of data evaluation (to produce recommended data), one should combine two data sets to produce the best guess data with the smallest possible uncertainty. In many situations, it is possible to assess the accuracy of theoretical calculations because theoretical models usually rely on parameters that are uncertain, but not completely random, i.e. the uncertainties of the parameters of the models are approximately known. If there are one or several such parameters with corresponding uncertainties, even if some or all parameters are correlated, the above approach gives a conceptually simple way to calculate uncertainties of final cross sections (uncertainty propagation). Numerically, the statistical approach to the uncertainty propagation could be computationally expensive. However, in situations, where uncertainties are considered to be as important as the actual cross sections (for data validation or benchmark calculations, for example), such a numerical effort is justified. Having data from different sources (say, from theory and experiment), a systematic statistical approach allows one to compare the data and produce “unbiased” evaluated data with improved uncertainties, if uncertainties of initial data from different sources are available. Without uncertainties, the data evaluation/validation becomes impossible. This is the reason why theoreticians should assess the accuracy of their calculations in one way or another. A statistical and systematic approach, similar to the described above, is preferable.
DEFF Research Database (Denmark)
Stevens, Thomas; Lu, HY
2009-01-01
Understanding loess sedimentation rates is crucial for constraining past atmospheric dust dynamics, regional climatic change and local depositional environments. However, the derivation of loess sedimentation rates is complicated by the lack of available methods for independent calculation......) the influences on sediment grain-size and accumulation; and (ii) their relationship through time and across the depositional region. This uncertainty has led to the widespread use of assumptions concerning the relationship between sedimentation rate and grain-size in order to derive age models and climate...... reconstructions. To address this uncertainty, detailed independent age models, based on optically stimulated luminescence dating, undertaken at 10 to 40 cm intervals at five sections across the Loess Plateau in China, have been used to calculate sedimentation rates and make comparisons with grain-size changes...
Brausch, Kathryn A; Anderson, Todd A; Smith, Philip N; Maul, Jonathan D
2010-11-01
Incorporation of carbon nanomaterials into industrial and consumer products is increasing, yet their impact on aquatic ecosystems alone and in chemical mixtures is largely unknown. Carbon nanomaterials may be found in the aquatic environment as mixtures with pesticides because of their proposed use in agriculture as smart delivery systems and nanosensors. The interaction effects of a functionalized fullerene ([1,2-methanofullerene C₆₀]-61-carboxylic acid) (fC₆₀) at 52.8 µg/L and the hydrophobic pesticides bifenthrin and tribufos were examined. The test organism was Daphnia magna, and response variables included 48-h survival, reproduction (bifenthrin, 70-d; tribufos, 21-d), and 10-d growth. Both pesticides reduced D. magna survival and reproduction (p bifenthrin acute toxicity but did not significantly affect chronic endpoints or growth (p > 0.05). Median lethal concentrations (LC50s), median inhibition concentrations (IC50s) for days surviving, and IC50s for reproduction were 0.86, 0.55, and 0.49 µg/L for bifenthrin; 0.22, 0.39, and 0.77 µg/L for fC₆₀-bifenthrin mix; 6.63, 9.89, and 5.79 µg/L for tribufos; and 9.17, 8.17, and 6.59 µg/L for fC₆₀-tribufos mix. Mixtures did not affect instantaneous growth rate (p > 0.05). These results suggest that fC₆₀ had little effect on pesticide chronic toxicity but influenced acute toxicity. Given the widespread application of nanotechnology, the influence of nanomaterials on environmental contaminants is an important consideration. Thus, our results may be useful in the development and use of nanotechnology in agricultural practices. © 2010 SETAC.
Directory of Open Access Journals (Sweden)
Michelle Pirrie Stockwell
Full Text Available The amphibian chytrid fungus Batrachochytrium dendrobatidis is a recently emerged pathogen that causes the infectious disease chytridiomycosis and has been implicated as a contributing factor in the global amphibian decline. Since its discovery, research has been focused on developing various methods of mitigating the impact of chytridiomycosis on amphibian hosts but little attention has been given to the role of antifungal agents that could be added to the host's environment. Sodium chloride is a known antifungal agent used routinely in the aquaculture industry and this study investigates its potential for use as a disease management tool in amphibian conservation. The effect of 0-5 ppt NaCl on the growth, motility and survival of the chytrid fungus when grown in culture media and its effect on the growth, infection load and survivorship of infected Peron's tree frogs (Litoria peronii in captivity, was investigated. The results reveal that these concentrations do not negatively affect the survival of the host or the pathogen. However, concentrations greater than 3 ppt significantly reduced the growth and motility of the chytrid fungus compared to 0 ppt. Concentrations of 1-4 ppt NaCl were also associated with significantly lower host infection loads while infected hosts exposed to 3 and 4 ppt NaCl were found to have significantly higher survival rates. These results support the potential for NaCl to be used as an environmentally distributed antifungal agent for the prevention of chytridiomycosis in susceptible amphibian hosts. However, further research is required to identify any negative effects of salt exposure on both target and non-target organisms prior to implementation.
International Nuclear Information System (INIS)
Jones, J.A.
1980-03-01
Radioactive material may be discharged to atmosphere in small quantities during the normal operation of a nuclear installation as part of a considered waste management practice. Estimates of the individual and collective dose equivalent rates resulting from such a discharge are required in a number of contexts: for example, in assessing compliance with dose limits, in estimating the radiological impact of the discharge and as an input into optimisation studies. The suite of programs which has been developed to undertake such calculations is made up of a number of independent modules one of which, ESCLOUD, is described in this report. The ESCLOUD program evaluates, as a function of distance and direction from the release point, the air concentration, deposition rate and external β and γ doses from airborne and deposited activity. The air concentration and deposition rate can be used as input to other modules for calculating inhalation and ingestion doses. (author)
Effect of clearcutting operations on the survival rate of a small mammal.
Directory of Open Access Journals (Sweden)
Martín A H Escobar
Full Text Available Clearcutting is a common timber harvesting technique that represents a significant and abrupt change in habitat conditions for wildlife living in industrial forests. Most research on this type of impact has focused on comparing populations or communities in mature forests/plantations and the resulting clearcut stands. However, this approach does not separate the effect of changes in habitat attributes from direct mortality produced by the intensive use of heavy machinery required for cutting down trees and dragging them to a road. Because knowing the fate of individuals after a disturbance is important for modelling landscape-scale population dynamics in industrial forests, we conducted a study in South-Central Chile to understand the short-term response to clearcutting operations of the long-haired Akodont (Abrothrix longipillis, a forest specialist mouse. Between 2009 and 2013 we radiotracked a total of 51 adult male Akodonts, before, during and after the clearcutting of the pine plantations in which they lived. A minimum of 52.4% of the individuals died as a direct cause of the timbering operations, being crushed by vehicles or logs during logging operations. Our observations suggest that, instead of fleeing the area, the response of long-haired Akodonts to the approaching machinery is to hide under the forest litter or in burrows, which exposes them to a serious risk of death. The real mortality rate associated to clearcutting may be higher than that estimated by us because of some methodological biases (i.e. individuals with crushed radiotransmitters not recorded and the fact that additional mortality sources may affect the population in the weeks following logging operations (e.g., higher exposure to predation, effects of site preparation for the new plantation, etc.
Effect of oxaliplatin on the survival rate of human Y79 cells after down-regulation of Mcl-1
Directory of Open Access Journals (Sweden)
Lu Zhou
2017-12-01
Full Text Available AIM: To study the effect of oxaliplatin on the survival rate of Y79 after down-regulation of Mcl-1 by SiRNA. METHODS: Y79 cells were cultured in RPMI1640. The cultured cells were stimulated with 0.25μmol/L of oxaliplatin. The expression of Mcl-1 protein was detected by Western blot after 6, 16 and 24h respectively. Cells in logarithmic phase were collected and used for single-cell suspension. Then they were transfected with empty plasmid, Mcl-1-homo-991, Mcl-1-homo-1114 and Mcl-1-homo-1235. After 6h, fluorescence microscope was used to observe the transfection efficiency and the optimal one was selected. The cells were divided into Group A and transfected with empty plasmids. The cells transfected with Mcl-1 were divided into Group B and Group C. Group A and Group C were treated with 0.25μmol/L oxaliplatin for stimulating induction, and the apoptotic rate was compared after 24h.RESULTS: The expression of Mcl-1 in Y79 stimulated by oxaliplatin was the most after 24h of culture. Mcl-1-homo-991 significantly inhibited the expression of Mcl-1 in Y79 after transfection. There was no significant difference in the apoptosis rate in Group A(11.1%±1.2%and in the control group(6.1%±0.6%(P>0.05. The apoptotic rate of Group C(49.2%±2.7%was significantly higher than that of Group B(20.8%±1.9%. At the same time, the apoptotic rates of these two groups were significantly higher than those of Group A and control group, the difference was statistically significant(PCONCLUSION:Downregulation of Mcl-1 by siRNA can reduce the drug resistance of Y79, thereby enhancing the apoptosis of Y79, and reducing the survival rate of Y79.
The problem of reactivity and reaction-rate calculations for mixed graphite lattices
International Nuclear Information System (INIS)
Pitcher, H.H.W.
1963-05-01
The dependence of reactor physics quantities, such as η f and Pu239/U235 fission ratio, in a single cell on the environment of the cell, and the relationship of the reactivity of a mixed lattice to the reactivity of its components, in graphite-moderated reactors are investigated. In a particular case, a mixed lattice fuelled with uranium at 0 and 3000 MWD/Te showed at 8 cm. pitch a small but appreciable change (∼ 1%) in cell quantities, and at 25 cm. pitch a smaller change. It is found that the present method of calculating lattice reactivity, ignoring intercell effects, is probably adequate for standard-pitch metal-fuelled graphite-moderated systems. More general mixed-lattice systems, particularly if accurate values of cell quantities are required, may need special calculation techniques; these are discussed, and techniques adequate for most systems are presented. (author)
International Nuclear Information System (INIS)
Esteve Sanchez, S.; Martinez Albaladejo, M.; Garcia Fuentes, J. D.; Bejar Navarro, M. J.; Capuz Suarez, B.; Moris de Pablos, R.; Colmenares Fernandez, R.
2015-01-01
We assessed the reliability of the program with 80 patients in the usual points of prescription of each pathology. The average error of the calculation points is less than 0.3% in 95% of cases, finding the major differences in the axes of the applicators (maximum error -0.798%). The program has proved effective previously testing him with erroneous dosimetry. Thanks to the implementation of this program is achieved by the calculation of the dose and part of the process of quality assurance program in a few minutes, highlighting the case of HDR prostate due to having a limited time. Having separate data sheet allows each institution to its protocols modify parameters. (Author)
A fracture- mechanics calculation of crack growth rate for a gas turbine blade
International Nuclear Information System (INIS)
Mirzaei, M.; Karimi, R.
2002-01-01
The existence of thermo-mechanical stresses, due to the frequent start-ups and shutdowns of gas turbines. Combined with high working temperatures may cause creep and fatigue failure of the blades. This paper describes a fracture-mechanics life assessment of a gas turbine blade. Initially, the distributions of thermal and mechanical stresses were obtained by using the finite element method. Accordingly; the crack modeling was performed in a high stress region at the suction side surface of the blade. Several crack growth increments were observed and the related crack tip parameters were calculated. Finally; the creep-fatigue crack growth in each cycle was calculated and the total number of start-stop cycles was determined
International Nuclear Information System (INIS)
Phillips, R.L.; London, E.D.; Links, J.M.; Cascella, N.G.
1990-01-01
A program was developed to align positron emission tomography images from multiple studies on the same subject. The program allowed alignment of two images with a fineness of one-tenth the width of a pixel. The indications and effects of misalignment were assessed in eight subjects from a placebo-controlled double-blind crossover study on the effects of cocaine on regional cerebral metabolic rates for glucose. Visual examination of a difference image provided a sensitive and accurate tool for assessing image alignment. Image alignment within 2.8 mm was essential to reduce variability of measured cerebral metabolic rates for glucose. Misalignment by this amount introduced errors on the order of 20% in the computed metabolic rate for glucose. These errors propagate to the difference between metabolic rates for a subject measured in basal versus perturbed states
Automated Discovery of New Chemical Reactions and Accurate Calculation of Their Rates
2015-06-02
chemistry calculations are run. The product matrices P are obtained and converted to block structure by simple linear algebra operations...in the system, i.e. 0 , =∑ ji ija Usually in elementary reactions |aij|ɛ since the change by two implies a significant chemical process, for...instance, formation or rupture of a double bond in a single elementary step. After applying the reaction matrix A, the product matrix P can then be
International Nuclear Information System (INIS)
Li Chunjuan; Liu Yi'na; Zhang Weihua; Wang Zhiqiang
2014-01-01
The manganese bath method for measuring the neutron emission rate of radionuclide sources requires corrections to be made for emitted neutrons which are not captured by manganese nuclei. The Monte Carlo particle transport code MCNP was used to simulate the manganese bath system of the standards for the measurement of neutron source intensity. The correction factors were calculated and the reliability of the model was demonstrated through the key comparison for the radionuclide neutron source emission rate measurements organized by BIPM. The uncertainties in the calculated values were evaluated by considering the sensitivities to the solution density, the density of the radioactive material, the positioning of the source, the radius of the bath, and the interaction cross-sections. A new method for the evaluation of the uncertainties in Monte Carlo calculation was given. (authors)
International Nuclear Information System (INIS)
Grebner, H.; Hoefler, A.; Hunger, H.
1991-01-01
In this paper calculations to experiments on leak opening and leak rates of piping components are presented. The experiments are performed at the HDR-facility at Karlstein/Germany and up to now straight pipes and pipe branches were considered. Numerical and experimental results are compared. (author)
International Nuclear Information System (INIS)
Cota, P.L.
1987-01-01
The used methods for calculating the rate and area of sedimentation are based in techniques of graphical resolution. The solution of the problem by a mathematical resolution, using computational methods, is more fast and more accuracy. The comparison between the results from this methods and the conventional method is shown. (E.G.) [pt
Feenstra, K Anton; Peter, Christine; Scheek, Ruud M; van Gunsteren, Wilfred F; Mark, Alan E
Three methods for calculating nuclear magnetic resonance cross-relaxation rates from molecular dynamics simulations of small flexible molecules have been compared in terms of their ability to reproduce relaxation data obtained experimentally and to produce consistent descriptions of the system. The
Directory of Open Access Journals (Sweden)
Dahi M
2015-02-01
Full Text Available Background and Objective: Cardiopulmonary resuscitation (CPR is performed in order to restore the functioning of two most important body organs the heart and brain. The present study was performed to investigate the effect of retraining of nurses on CPR success rate and short-term and long-term CPR survival. Materials and Method: The study population of the present quasi-experimental study consisted of all nurses of Taleghani Hospital affiliated with Shahid Beheshti University, Tehran, Iran, in 2011. The study subjects (n = 400 were selected using convenience and purposive sampling method. The patient survival rate during the first 24 hours (short-term survival and discharge from the hospital (long-term survival after CPR were reported. Then, the study subjects, in groups of 20, participated in CPR training courses. Short-term (24 hours and long-term (discharge from hospital in good mental status survival subsequent to CPR were reevaluated and compared with pre-training results. Data were analyzed using SPSS software version 20, and t-test and chi-square test. Results: Retraining promoted CPR success rates. This increase in the short-term success rate was not significant, but the increase in long-term success rate was statistically significant (P = 0.007. Conclusion: Periodic retraining of nurses may improve CPR success rate particularly long-term survival or discharge from hospital. Therefore, further studies on long-term success of CPR considering confounding factors are recommended
Directory of Open Access Journals (Sweden)
Elrifadah Elrifadah
2016-10-01
Full Text Available This study Aims to Determine the effect of different variations on survival seed cicada goldfish. The method used in this study is completely randomized design with 3 treatments (A = 3%, B = 5%, and C = 7% and three replications. From these results Obtained survival rate to 83.0% Obtained treatment A, B Obtained 88.33% and 80.0% Obtained C treatment. Then the results of analysis of variance accept the hypothesis Ho that the percentage variation of different cicada extract (3%, 5% and 7% did not Affect the survival rate of seedlings goldfish. During the last condition of water quality research support for seed viability parameters goldfish.
Calculation of astrophysical S-factor and reaction rate in 12C(p, γ)13N reaction
Moghadasi, A.; Sadeghi, H.; Pourimani, R.
2018-02-01
The 12C(p, γ)13N reaction is the first process in the CNO cycle. Also it is a source of low-energy solar neutrinos in various neutrino experiments. Therefore, it is of high interest to gain data of the astrophysical S-factor in low energies. By applying Faddeev's method, we calculated wave functions for the bound state of 13N. Then the cross sections for resonance and non-resonance were calculated through using Breit-Wigner and direct capture cross section formulae, respectively. After that, we calculated the total S-factor and compared it with previous experimental data, revealing a good agreement altogether. Then, we extrapolated the S-factor in zero energy and the result was 1.32 ± 0.19 (keV.b). In the end, we calculated reaction rate and compared it with NACRE data.
Calculation on cosmic-ray muon exposure rate in non-walled concrete buildings
International Nuclear Information System (INIS)
Fujitaka, Kazunobu; Abe, Siro
1984-01-01
Computer simulations on the exposure indoors from cosmic ray muons were practiced in the framework of non-scattering and non-cascade assumptions. The model buildings were two-dimensional, rectangular, and were made of a normal concrete. A stratified structure was assumed in each building, where no mezzanine was considered. Walls were not taken into account yet. The distributions of the exposure rates in 26-story buildings were illustrated in contour maps for various sets of parameters. All of them gave basically archlike patterns. Analyses of the results showed that the exposure rate is affected most largely by the floor board thickness. The ceiling height would be an insignificant factor for short buildings. The min/max ratio of the muon exposure rate in a moderate size building was estimated to be more than 0.7. (author)
Directory of Open Access Journals (Sweden)
Alena JEŽKOVÁ
2008-11-01
Full Text Available The objective of this study was to determine the relationship between calving year and season, parity, number of AI, day of lactation, milk production in the 1st 100 lactation days or diseases occurrence (retained placenta, endometritis or cysts, sperm motility (SM during 30, 60 and 90 minutes of the cervical mucus survival test, cervical mucus crystallization (CMC and their infl uence on days to fi rst insemination (interval, open days (SP, inseminations number for pregnancy (index, and pregnancy rates (PR in Holstein cows (n=284. Signifi cant differences of interval, SP and index were detected also in relation to number of AI and day of lactation (P < 0.001. Cows without reproduction diseases (healthy had better results of interval, SP (P < 0.01, index and PR. Pregnancy rate of healthy cows was by 11.43% higher, but without statistical signifi cance. The higher results of PR (62.74% were discovered in relation to ferny-like crystallization of cervical mucus (P < 0.001. CMC affected results of cervical mucus survival test, the highest motility of sperms after the 60 and 90 minutes was assumed in the case of club moss – ferny (14.80% and 7.96% and ferny-like crystallization (13.82% and 8.47% with statistical signifi cance (P < 0.05. The choice of these characteristics and defi nition of their relations allows assuming their using for detailed study and determination of the cows´ biological ability to conceive, the one of the main components of effi ciency of cows´ reproduction.
Koller, Kristian M; Mackley, Heath B; Liu, Jason; Wagner, Henry; Talamo, Giampaolo; Schell, Todd D; Pameijer, Colette; Neves, Rogerio I; Anderson, Bryan; Kokolus, Kathleen M; Mallon, Carol A; Drabick, Joseph J
2017-01-02
There is a growing body of evidence supporting the synergistic roles of radiotherapy and immunotherapy in the treatment of malignancy. Published case studies of the abscopal effect have been reported with the use of ipilimumab and radiotherapy in metastatic melanoma, but evidence supporting the routine use of this combination of therapy is limited. We conducted a retrospective analysis to evaluate patients treated with ipilimumab for advanced melanoma at a single institution from May 2011 to June 2015. Patients were grouped into those who had received concurrent radiotherapy while on ipilimumab (Ipi-RT), and those who did not. We then evaluated the treatment response following completion of ipilimumab. A total of 101 patients received ipilimumab in the prespecified time frame. 70 received Ipi-RT and 31 received ipilimumab without concurrent radiotherapy. Median overall survival (OS) was significantly increased in the concurrent Ipi-RT arm at 19 months vs. 10 months for ipilimumab alone (p = 0.01). Median progression free survival (PFS) was marginally increased in the Ipi-RT group compare with the ipilimumab alone group (5 months vs. 3 months, p = 0.20). Rates of complete response (CR) were significantly increased in the Ipi-RT group vs. ipilimumab alone (25.7% vs. 6.5%; p = 0.04), and rates of overall response (OR) in the groups were 37.1% vs. 19.4% (p = 0.11). No increase in toxicities was observed in the Ipi-RT group compare with ipilimumab alone. Prospective trials are needed to further clarify the role of radiotherapy with ipilimumab, but these encouraging preliminary observations suggest that this combination can induce more durable responses to immunotherapy.
Status of the fuel stress and failure rate calculations at KFA
International Nuclear Information System (INIS)
Bongartz, K.
1980-11-01
In this report a new model for calculating stresses in the SiC layer of TRISO coated particles is presented. The gain in computer time with respect to the Walther model used up to now is a factor of 100. The restrictions of this model are - application is only possible to TRISO particles and not BISO which can be handled with the Walther model as well, the SiC layer is regarded as rigid: in fact, its Young's modulus is higher by a factor of 10 as compared to that of the Pyrocarbon layers. (orig.) [de
Multiconfiguration Dirac-Hartree-Fock calculations of energy levels and radiative rates of Fe VII
Li, Yang; Xu, Xiaokai; Li, Bowen; Jönsson, Per; Chen, Ximeng
2018-06-01
Detailed calculations are performed for 134 fine-structure levels of the 3p63d2, 3p63d4s, 3p53d3 and 3p63d4p configurations in Fe VII using the multiconfiguration Dirac-Hartree-Fock (MCDHF) and relativistic configuration interaction (RCI) methods. Important electron correlation effects are systematically accounted for through active space (AS) expansions. Our results compare well with experimental measurements, emphasizing the importance of a careful treatment of electron correlation, and provide some missing data in the NIST atomic database. The data obtained are expected to be useful in astrophysical applications, particularly for the research of the solar coronal plasma.
Shell-model calculations of beta-decay rates for s- and r-process nucleosyntheses
International Nuclear Information System (INIS)
Takahashi, K.; Mathews, G.J.; Bloom, S.D.
1985-01-01
Examples of large-basis shell-model calculations of Gamow-Teller β-decay properties of specific interest in the astrophysical s- and r- processes are presented. Numerical results are given for: (1) the GT-matrix elements for the excited state decays of the unstable s-process nucleus 99 Tc; and (2) the GT-strength function for the neutron-rich nucleus 130 Cd, which lies on the r-process path. The results are discussed in conjunction with the astrophysics problems. 23 refs., 3 figs
The inclusion of shadowing effect in the reaction-rates calculation
International Nuclear Information System (INIS)
Monteiro, M.A.M.
1990-03-01
A method for the Resonance Integral calculation in the fuel and moderator regions is presented including the Shadowing effect. This effect appears due to the presence of several fuel rods in a infinite moderator region. The method is based on the approximations to the J (ζ, β) function and theirs partial derivatives in relation to β. The dependence of the Resonance Integral in the J (ζ, β) comes from the rational approximation to the neutron escape probability. The final results are obtained in a very simple and fast way, and show the good accuracy of the method. (author)
Variational RRKM calculation of thermal rate constant for C–H bond fission reaction of nitro methane
Directory of Open Access Journals (Sweden)
Afshin Taghva Manesh
2017-02-01
Full Text Available The present work provides quantitative results for the rate constants of unimolecular C–H bond fission reactions in the nitro methane at elevated temperatures up to 2000 K. In fact, there are three different hydrogen atoms in the nitro methane. The potential energy surface for each C–H bond fission reaction of nitro methane was investigated by ab initio calculations. The geometry and vibrational frequencies of the species involved in this process were optimized at the MP2 level of theory, using the cc-pvdz basis set. Since C–H bond fission channel is a barrierless reaction, we have used variational RRKM theory to predict rate coefficients. By means of calculated rate coefficients at different temperatures, the Arrhenius expression of the channel over the temperature range of 100–2000 K is k(T = 5.9E19∗exp(−56274.6/T.
User's guide to SERICPAC: A computer program for calculating electric-utility avoided costs rates
Energy Technology Data Exchange (ETDEWEB)
Wirtshafter, R.; Abrash, M.; Koved, M.; Feldman, S.
1982-05-01
SERICPAC is a computer program developed to calculate average avoided cost rates for decentralized power producers and cogenerators that sell electricity to electric utilities. SERICPAC works in tandem with SERICOST, a program to calculate avoided costs, and determines the appropriate rates for buying and selling of electricity from electric utilities to qualifying facilities (QF) as stipulated under Section 210 of PURA. SERICPAC contains simulation models for eight technologies including wind, hydro, biogas, and cogeneration. The simulations are converted in a diversified utility production which can be either gross production or net production, which accounts for an internal electricity usage by the QF. The program allows for adjustments to the production to be made for scheduled and forced outages. The final output of the model is a technology-specific average annual rate. The report contains a description of the technologies and the simulations as well as complete user's guide to SERICPAC.
Directory of Open Access Journals (Sweden)
Mohammed S. Al-Jawad
2017-11-01
Full Text Available Multilateral wells require a sophisticated type of well model to be applied in reservoir simulators to represent them. The model must be able to determine the flow rate of each fluid and the pressure throughout the well. The production rate calculations are very important because they give an indication about some main issues associated with multi-lateral wells such as one branch may produce water or gas before others, no production rate from one branch, and selecting the best location of a new branch for development process easily. This paper states the way to calculate production rate of each branch of a multilateral well-using multi-segment well model. The pressure behaviour of each branch is simulated dependent on knowing its production rate. This model has divided a multi-lateral well into an arbitrary number of segments depending on the required degree of accuracy and run time of the simulator. The model implemented on a field example (multi-lateral well HF-65ML in Halfaya Oil Field/Mishrif formation. The production rate and pressure behaviour of each branch are simulated during the producing interval of the multilateral well. The conclusion is that production rate of the main branch is slightly larger than a lateral branch.
Calculating second derivatives of population growth rates for ecology and evolution
Shyu, E.; Caswell, H.
2014-01-01
Second derivatives of the population growth rate measure the curvature of its response to demographic, physiological or environmental parameters. The second derivatives quantify the response of sensitivity results to perturbations, provide a classification of types of selection and provide one way
International Nuclear Information System (INIS)
Nabi, Jameel-Un
2010-01-01
An accurate estimate of the neutrino cooling rates is required in order to study the various stages of stellar evolution of massive stars. Neutrino losses from proto-neutron stars play a crucial role in deciding whether these stars would be crushed into black holes or explode as supernovae. Both pure leptonic and weak-interaction processes contribute to the neutrino energy losses in stellar matter. At low temperatures and densities, the characteristics of the early phase of presupernova evolution, cooling through neutrinos produced via the weak interaction, are important. Proton-neutron quasi-particle random phase approximation (pn-QRPA) theory has recently been used with success for the calculation of stellar weak-interaction rates of fp-shell nuclide. The lepton-to-baryon ratio (Y e ) during early phases of stellar evolution of massive stars changes substantially, mainly due to electron captures on 56 Ni. The stellar matter is transparent to the neutrinos produced during the presupernova evolution of massive stars. These neutrinos escape the site and assist the stellar core in maintaining a lower entropy. Here, an expanded calculation of weak-interaction-mediated neutrino and antineutrino cooling rates due to 56 Ni in stellar matter using the pn-QRPA theory is presented. This detailed scale is appropriate for interpolation purposes and is of greater utility for simulation codes. The calculated rates are compared with earlier calculations. During the relevant temperature and density regions of stellar matter the reported rates show few differences compared with the shell model rates and might contribute in fine-tuning of the lepton-to-baryon ratio during the presupernova phases of stellar evolution of massive stars.
Directory of Open Access Journals (Sweden)
Chun-Ming Chang
Full Text Available BACKGROUND: Positive results between caseloads and outcomes have been validated in several procedures and cancer treatments. However, there is limited information available on the combined effects of surgeon and hospital caseloads. We used nationwide population-based data to explore the association between surgeon and hospital caseloads and survival rates for major cancers. METHODOLOGY: A total of 11,677 patients with incident cancer diagnosed in 2002 were identified from the Taiwan National Health Insurance Research Database. Survival analysis, the Cox proportional hazards model, and propensity scores were used to assess the relationship between 5-year survival rates and different caseload combinations. RESULTS: Based on the Cox proportional hazard model, cancer patients treated by low-volume surgeons in low-volume hospitals had poorer survival rates, and hazard ratios ranged from 1.3 in head and neck cancer to 1.8 in lung cancer after adjusting for patients' demographic variables, co-morbidities, and treatment modality. When analyzed using the propensity scores, the adjusted 5-year survival rates were poorer for patients treated by low-volume surgeons in low-volume hospitals, compared to those treated by high-volume surgeons in high-volume hospitals (P<0.005. CONCLUSIONS: After adjusting for differences in the case mix, cancer patients treated by low-volume surgeons in low-volume hospitals had poorer 5-year survival rates. Payers may implement quality care improvement in low-volume surgeons.
Calculations of the Auger deexcitation rate of dtμ within the muonic quasimolecule (dtμ)dee
Armour, E. A. G.; Lewis, D. M.; Hara, S.
1992-12-01
A key process in muon-catalyzed fusion is the deexcitation of dtμ within the resonant muonic quasimolecule (dtμ)dee, by emission of an Auger electron. The dtμ in the quasimolecule is initially in a weakly bound excited state with J=1 and v=1. Calculations are carried out of the rate of the dominant transition to the state with J=0 and v=1. Use is made of the dipole matrix element obtained for this transition by Scrinzi and Szalewicz [Phys. Rev. A 39, 2855 (1989)]. Full account is taken of the molecular nature of the quasimolecule. The continuum electronic wave functions for the Auger electron for all four contributing symmetries, i.e., Σ+g, Σ+u, Πu, and Πg, are first obtained by a two-center Coulomb calculation and a static-exchange calculation, extended to include dipole polarization. Comparison is then made with the results of a calculation in which the Σ+μ and Πu wave functions are obtained as in a previous paper by Armour and Lewis [J. Phys. B 23, L25 (1990)] and the Σ+g and Πg wave functions are obtained by the Kohn method. There are significant differences between the contributions from the individual symmetries, but the overall values for the deexcitation rate are all of the same order of magnitude as the results of earlier calculations.
Bi, Ran; Liu, Peng
2016-03-31
RNA-Sequencing (RNA-seq) experiments have been popularly applied to transcriptome studies in recent years. Such experiments are still relatively costly. As a result, RNA-seq experiments often employ a small number of replicates. Power analysis and sample size calculation are challenging in the context of differential expression analysis with RNA-seq data. One challenge is that there are no closed-form formulae to calculate power for the popularly applied tests for differential expression analysis. In addition, false discovery rate (FDR), instead of family-wise type I error rate, is controlled for the multiple testing error in RNA-seq data analysis. So far, there are very few proposals on sample size calculation for RNA-seq experiments. In this paper, we propose a procedure for sample size calculation while controlling FDR for RNA-seq experimental design. Our procedure is based on the weighted linear model analysis facilitated by the voom method which has been shown to have competitive performance in terms of power and FDR control for RNA-seq differential expression analysis. We derive a method that approximates the average power across the differentially expressed genes, and then calculate the sample size to achieve a desired average power while controlling FDR. Simulation results demonstrate that the actual power of several popularly applied tests for differential expression is achieved and is close to the desired power for RNA-seq data with sample size calculated based on our method. Our proposed method provides an efficient algorithm to calculate sample size while controlling FDR for RNA-seq experimental design. We also provide an R package ssizeRNA that implements our proposed method and can be downloaded from the Comprehensive R Archive Network ( http://cran.r-project.org ).
Energy Technology Data Exchange (ETDEWEB)
Halama, Arthur; Kamerdzhiev, Vsevolod; Boehme, Christian; Srinivasan, Sudharsan [Forschungszentrum Juelich, IKP-4 (Germany)
2016-07-01
The institute of Nuclear Physics 4(IKP-4) of the Research Center Juelich (FZJ) is in charge of building and commissioning the High Energy Storage Ring (HESR) within the international Facility for Antiproton and Ion Research (FAIR) at Darmstadt. Simulations and numerical calculations were performed to characterize the initial beam position pickup design. Capacitive couplings of the electrodes and the behavior of the electrical equivalent circuit were investigated. This made room for changes to the design and performance increase. A prototype of the BPM pickup was constructed and tested on a dedicated test bench. Preliminary results will be presented. In order to gain higher signal levels and higher sensitivity, another suggested design was characterized as well and put into comparison.
Concept for calculating dose rates from activated groundwater at accelerator sites
Prolingheuer, N; Vanderborght, J; Schlögl, B; Nabbi, R; Moormann, R
Licensing of particle accelerators requires the proof that the groundwater outside of the site will not be significantly contaminated by activation products formed below accelerator and target. In order to reduce the effort for this proof, a site independent simplified but conservative method is under development. The conventional approach for calculation of activation of soil and groundwater is shortly described on example of a site close to Forschungszentrum Juelich, Germany. Additionally an updated overview of a data library for partition coefficients for relevant nuclides transported in the aquifer at the site is presented. The approximate model for transport of nuclides with ground water including exemplary results on nuclide concentrations outside of the site boundary and of resulting effective doses is described. Further applications and developments are finally outlined.
International Nuclear Information System (INIS)
Berzonis, M.A.; Bondars, H.Ya.
1981-08-01
A brief description of the SAIPS software and the basic principles of its application is given. SAIPS contains programs needed to unfold spectra, libraries of neutron cross sections and reference spectra, and software for automatic calculation and for system maintenance. SAIPS offers the possibility of determining the reliability of an unfolded neutron spectrum and of planning measurements and calculations by varying different factors: the errors in the reaction rates, the errors in the cross sections used, the detector assembly, the unfolding programs, etc. SAIPS runs on the ES 1022 computer
International Nuclear Information System (INIS)
Pereira, W.S.; Moraes, S.R.; Cavalcante, J.J.V.; Pinto, C.E.C.; Kelecom, A.
2017-01-01
Areas of increased radiation may expose biota to radiation doses greater than the world averages, and depending on the magnitude of the exposure causing biota damage. The region of the municipality of Caldas, MG, BR is considered a region of increased natural radioactivity. The present work aims to evaluate the exposure of biota to natural radionuclides in the region of Caldas, MG. In order to evaluate the biota exposure in the region, the concentrations of the natural radionuclides U nat , 226 Ra, 210 Pb and 232 Th and 228 Ra were evaluated in two species of fishes: lambari (Astymax spp.) And traíra (Hoplias spp.). The dose rates of the analyzed fish were: for Astymax spp of 0.08 μGy d -1 and for Hoplias spp of 0.12 μGy∙d -1 . With these dose rate values no measurable deleterious effects are expected in the species studied
Stuebe, Alison M; Jegier, Briana J; Schwarz, Eleanor Bimla; Green, Brittany D; Reinhold, Arnold G; Colaizy, Tarah T; Bogen, Debra L; Schaefer, Andrew J; Jegier, Jamus T; Green, Noah S; Bartick, Melissa C
2017-12-01
We sought to determine the impact of changes in breastfeeding rates on population health. We used a Monte Carlo simulation model to estimate the population-level changes in disease burden associated with marginal changes in rates of any breastfeeding at each month from birth to 12 months of life, and in rates of exclusive breastfeeding from birth to 6 months of life. We used these marginal estimates to construct an interactive online calculator (available at www.usbreastfeeding.org/saving-calc ). The Institutional Review Board of the Cambridge Health Alliance exempted the study. Using our interactive online calculator, we found that a 5% point increase in breastfeeding rates was associated with statistically significant differences in child infectious morbidity for the U.S. population, including otitis media (101,952 cases, 95% confidence interval [CI] 77,929-131,894 cases) and gastrointestinal infection (236,073 cases, 95% CI 190,643-290,278 cases). Associated medical cost differences were $31,784,763 (95% CI $24,295,235-$41,119,548) for otitis media and $12,588,848 ($10,166,203-$15,479,352) for gastrointestinal infection. The state-level impact of attaining Healthy People 2020 goals varied by population size and current breastfeeding rates. Modest increases in breastfeeding rates substantially impact healthcare costs in the first year of life.
Ji, Woong Bae; Hong, Kwang Dae; Kim, Jung-Sik; Joung, Sung-Yup; Um, Jun Won; Min, Byung-Wook
2018-01-01
FOLFOX chemotherapy is widely used as an adjuvant treatment for advanced colon cancer. The duration of adjuvant chemotherapy is usually set to 6 months, which is based on a former study of 5-fluorouracil/leucovorin chemotherapy. However, the FOLFOX regimen is known to have complications, such as peripheral neuropathy. The aim of this study was to compare the survival rates and complications experienced by patients receiving either 4 or 6 months of FOLFOX chemotherapy. Retrospective data analysis was performed for stage II and III patients who underwent radical resection of colon cancer. We compared the 5-year survival rates and the occurrence of complications in patients who completed only 8 cycles of FOLFOX chemotherapy with patients who completed 12 cycles of chemotherapy. Among 188 patients who underwent adjuvant FOLFOX chemotherapy for stage II or III colon cancer, 83 (44.1%) completed 6 months of FOLFOX chemotherapy and 64 (34.0%) patients discontinued after 4 months of chemotherapy. The 5-year overall survival and disease-free survival rates did not show a significant difference. Patients in the 6-month group had peripheral neuropathy more frequently (p = 0.028). Five-year overall and disease-free survival were not significantly different between the 2 groups. Large-scale prospective studies are necessary for the analysis of complications and survival rates. © 2017 S. Karger AG, Basel.
International Nuclear Information System (INIS)
Kuwabara, Yoichi; Tamaki, Nagara; Nakata, Tomoaki; Yamashina, Shohei; Yamazaki, Junichi
2011-01-01
The goals of this meta-analysis were to determine survival rates in patients with heart failure (HF) assessed by 123 I-metaiodobenzylguanidine (MIBG) imaging results using recently published studies and to determine the prognostic value of 123 I-MIBG imaging. We reviewed published cohort studies carried out in Japan that compared the prognosis of patients with their 123 I-MIBG activity quantified as late heart-to-mediastinum ratio (H/M) or washout rate by performing a PubMed search for articles in English up to December 2006. Studies were selected if they analyzed a clearly defined lethal outcome (cardiovascular death) using life tables to estimate the odds ratio at 24 months after enrollment. Of 158 articles related to cardiac 123 I-MIBG, seven referred to studies that met the inclusion criteria: 5 evaluated H/M via 123 I-MIBG in a total of 866 patients and 4 calculated washout rate in a total of 491 patients. A low H/M indicated a high risk of cardiac death: pooled odds ratio, 5.2; 95% confidence interval (CI) of 3.1-5.7. A high washout was also associated with lethal events with a pooled odds ratio of 2.8 (CI: 1.6-5.0). The association between washout and cardiac death was heterogeneous (Chi-square=11.0, P 123 I-MIBG studies conducted in Japan indicated that both a decreased cardiac 123 I-MIBG activity (H/M) and an increased washout rate are indicative of a poor prognosis in patients with chronic heart failure. (author)
International Nuclear Information System (INIS)
Baksi, Soham; Green, Chris
2007-01-01
We specify formulas for computing the rate of decline in economy-wide energy intensity by aggregating its two determinants-technical efficiency improvements in the various sectors of the economy, and shifts in economic activity among these sectors. The formulas incorporate the interdependence between sectoral shares, and establish a one-to-one relation between sectoral output and energy shares. This helps to eliminate future energy intensity decline scenarios which involve implausible values of either sectoral share. An illustrative application of the formulas is provided, using within-sector efficiency improvement estimates suggested by Lightfoot-Green and Harvey
Development of DUST: A computer code that calculates release rates from a LLW disposal unit
International Nuclear Information System (INIS)
Sullivan, T.M.
1992-01-01
Performance assessment of a Low-Level Waste (LLW) disposal facility begins with an estimation of the rate at which radionuclides migrate out of the facility (i.e., the disposal unit source term). The major physical processes that influence the source term are water flow, container degradation, waste form leaching, and radionuclide transport. A computer code, DUST (Disposal Unit Source Term) has been developed which incorporates these processes in a unified manner. The DUST code improves upon existing codes as it has the capability to model multiple container failure times, multiple waste form release properties, and radionuclide specific transport properties. Verification studies performed on the code are discussed
Song, Jeong Ah; Kim, Hee Joo; Hong, Seong Keun; Lee, Dong Hoon; Lee, Sang Won; Song, Chang Seon; Kim, Ki Taek; Choi, In Soo; Lee, Joong Bok; Park, Seung Yong
2016-02-01
Influenza viruses cause acute respiratory disease. Because of the high genetic variability of viruses, effective vaccines and antiviral agents are limited. Considering the fact that the site of influenza virus entry is the mucosa of the upper respiratory tract, probiotics that can enhance mucosal immunity as well as systemic immunity could be an important source of treatment against influenza infection. Mice were fed with Lactobacillus rhamnosus M21 or skim milk and were challenged with influenza virus. The resulting survival rate, lung inflammation, and changes in the cytokine and secretory immunoglobulin A (sIgA) levels were examined. Because of infection (influenza virus), all the mice in the control group and 60% of the mice in the L. rhamnosus M21 group died; however, the remaining 40% of the mice fed with L. rhamnosus M21 survived the infection. Pneumonia was severe in the control group but moderate in the group treated with L. rhamnosus M21. Although there were no significant changes in the proinflammatory cytokines in the lung lysates of mice collected from both groups, levels of interferon-γ and interleukin-2, which are representative cytokines of type I helper T cells, were significantly increased in the L. rhamnosus M21-treated group. An increase in sIgA as well as the diminution of inflammatory cells in bronchoalveolar lavage fluid was also observed in the L. rhamnosus M21-treated group. These results demonstrate that orally administered L. rhamnosus M21 activates humoral as well as cellular immune responses, conferring increased resistance to the host against influenza virus infection. Copyright © 2014. Published by Elsevier B.V.
Owlia, P; Vasei, M; Goliaei, B; Nassiri, I
2011-04-01
The interests in journal impact factor (JIF) in scientific communities have grown over the last decades. The JIFs are used to evaluate journals quality and the papers published therein. JIF is a discipline specific measure and the comparison between the JIF dedicated to different disciplines is inadequate, unless a normalization process is performed. In this study, normalized impact factor (NIF) was introduced as a relatively simple method enabling the JIFs to be used when evaluating the quality of journals and research works in different disciplines. The NIF index was established based on the multiplication of JIF by a constant factor. The constants were calculated for all 54 disciplines of biomedical field during 2005, 2006, 2007, 2008 and 2009 years. Also, ranking of 393 journals in different biomedical disciplines according to the NIF and JIF were compared to illustrate how the NIF index can be used for the evaluation of publications in different disciplines. The findings prove that the use of the NIF enhances the equality in assessing the quality of research works produced by researchers who work in different disciplines. Copyright © 2010 Elsevier Inc. All rights reserved.
A comparison of reaction rate calculations using Endf/B-VII with critical assembly measurements
International Nuclear Information System (INIS)
Wilkerson, C.; Mac Innes, M.; Barr, D.; Trellue, H.; MacFarlane, R.; Chadwick, M.
2008-01-01
We present critical assembly reaction rate data, and modeling of the same using the recently released Endf/B-VII library. While some of the experimental measurements were performed as long as 50 years ago, the results have not been widely used/available outside of Los Alamos. Over the years, a variety of target foils were fabricated and placed in differing neutron spectrum/fluence environments within critical assemblies. Neutron-induced reactions such as (n,γ), (n,2n), and (n,f) on these targets were measured, typically referenced to 235 U(n,f) or 239 Pu(n,f). Because the cross section for the latter reactions are now well known, these experiments provide a rich data set for testing evaluated cross sections. Due to the large variety of critical assemblies that were historically available at Los Alamos, it was possible to make measurements in spectral environments ranging from hard (Pu Jezebel, center of Pu Flattop) through intermediate (Big Ten) to degraded (reflector region of Flattop). This broad range of configurations allows us to test both the cross section magnitudes and their energy dependencies. We will present data, along with reaction rate predictions using primarily MCNP5 in conjunction with Endf/B-VII, for a number of target nuclei, including iridium, isotopes of uranium (e.g., 233, 235, 237, 238), neptunium (237), plutonium (239), and americium (241). (authors)
International Nuclear Information System (INIS)
Tsuboi, A.
1982-01-01
The effects of 60 Co γ-rays on cell clonogenicity and cell proliferation were examined in NRK cells in exponential and plateau growth phases during and after irradiation at various dose rates. The typical dese rate effect for the survival responses was observed between acute irradiation and continuous irradiation at dose rates of 9.6-44 rads/h. Similar dose rate effect for the perturbation of the proliferation was observed in exponentially growing cells during irradiation. Some differences were found in survival when the cells were exposed to γ-rays at 9.6 rads/h or at 13.7 rads/h. The survival curves of exponential phase cells irradiated at these dose rates showed a shape different from that observed in plateau phase cells. Namely, a steady state of survival appeared around an accumulated dose of 1000 rads (dose-rate of 9.6 rads/h) and an accumulated dose of 1500 rads (dose-rate of 13.7 rads/h) in the exponential phase cells, while such a steady state of survival was not detected in plateau phase cells after similar conditions of irradiation. Moreover, the extrapolation number of the survival curve was much larger at the lower dose rate in exponential phase cells, in contrast to a value of the unity oberved in plateau phase cells, The radiosensitivity of plateau phase cells was somewhat lower compared to exponential phase cells over the range of accumulated doses at the dose rates used. These differences in cellular responses to the radiation between the two phases could be explained by changes in cell proliferation, the redistribution of the cell cycle compartments and the repair capacity of cellular damage during irradiation. (author)
International Nuclear Information System (INIS)
Gibson, J.A.B.
1978-06-01
This report is a brief survey of the methods used for calculating the dose rate from deposited fallout and includes improvements in the computing techniques. The changes consist of (a) the use of a more exact allowance for weathering (b) the calculation doses to mid-month rather than end of each month (c) the inclusion of the contribution from Nb-95 in a more exact way to allow for its build-up and decay with time (d) the use of a more precise method for estimating the dose prior to 1954. The result is to increase the calculated total γ-ray dose from 1951 to 1976 by 17% from 153 to 179 mrad in air at 1 m with an increase of 11% in the beta-ray dose. The annual levels for natural γ and β radiation are 12 and 62 mrad respectively. (author)
International Nuclear Information System (INIS)
Sievers, Juergen; Heckmann, Klaus; Blaesius, Christoph
2015-06-01
For the demonstration of break preclusion for pressure retaining components in nuclear power plants, the nuclear safety standard KTA 3206 determines also the requirements for the leak-before-break verification. For this procedure, it has to be ensured that a wall-penetrating crack is subcritical with respect to instable growth, and that the resulting leakage under stationary operation conditions can be detected by a leak detection system. Within the scope of the project 3613R01332 analyses with respect to conservative estimates of the leak rates in case of detections regarding break preclusion were performed by means of leak rate models being available at GRS. For this purpose, conservative assumptions in the procedure were quantified by comparative calculations concerning selected leak rate experiments and the requirements regarding the determination of leak rates indicated in the KTA 3206 were verified and specified. Moreover, the models were extended and relevant recommendations for the calculation procedure were developed. During the investigations of leak rate tests the calculation methods were validated, qualified by means of both examples indicated in KTA 3206 and applied to a postulated leak accident in the cooling circuit of a PWR. For the calculation of leak rates several simplified solution methods which are included in the GRS program WinLeck were applied, and for the simulation of a leak accident the large-scale programs ANSYS Mechanical and ATHLET (thermohydraulics program developed by GRS) were used. When applying simplified methods for the calculation of leak rates using the limiting curve for the friction factor which has been derived during the project and which is included in the KTA 3206 attention has to be paid to the fact that in case of small flow lengths the entrance loss can dominate compared to the friction loss. However, the available data do not suffice in order to make a quantitative statement with respect to limits of applicability
Brugger, Markus; Assmann, R W; Forkel-Wirth, Doris; Menzel, Hans Gregor; Roesler, Stefan; Vincke, Helmut H
2005-01-01
Radiation protection of the personnel who will perform interventions in the LHC Beam Cleaning Insertions is mandatory and includes the design of equipment and the establishment of work procedures. Residual dose rates due to activated equipment are expected to reach significant values such that any maintenance has to be planned and optimized in advance. Three-dimensional maps of dose equivalent rates at different cooling times after operation of the LHC have been calculated with FLUKA. The simulations are based on an explicit calculation of induced radioactivity and of the transport of the radiation from the radioactive decay. The paper summarizes the results for the Beam Cleaning Insertions and discusses the estimation of individual and collective doses received by personnel during critical interventions, such as the exchange of a collimator or the installation of Phase 2. The given examples outline the potential and the need to optimize, in an iterative way, the design of components as well as the layout of ...
Directory of Open Access Journals (Sweden)
Xiao Qinghua
2016-03-01
Full Text Available Based on energy theory, energy release rate (EER and local energy release rate (LEER, a new index called FERR (Fractional Energy Release Rate is proposed, and this method can not only evaluate the risk of rock burst, but also can point out the location of high risk and the scale of rockburst. The FERR index is applied to the TBM assembling tunnel in Jinping Hydro Power Station II to evaluate the scale and intensity of rockburst, as well as the location where rockburst occurs. With FDM method adopted, the energy release rate of 3 excavation plans are calculated and the scale and risk of rockburst is evaluated, and the location of high risk of rockburst is also mapped. With FERR used in the evaluation, the rockburst is nicely controlled which ensured the safety and construction schedule of the project.
Directory of Open Access Journals (Sweden)
Stephen Carstens
2008-11-01
Full Text Available Companies tend to outsource transport to fleet management companies to increase efficiencies if transport is a non-core activity. The provision of fleet management services on contract introduces a certain amount of financial risk to the fleet management company, specifically fixed rate maintenance contracts. The quoted rate needs to be sufficient and also competitive in the market. Currently the quoted maintenance rates are based on the maintenance specifications of the manufacturer and the risk management approach of the fleet management company. This is usually reflected in a contingency that is included in the quoted maintenance rate. An alternative methodology for calculating the average maintenance cost for a vehicle fleet is proposed based on the actual maintenance expenditures of the vehicles and accepted statistical techniques. The proposed methodology results in accurate estimates (and associated confidence limits of the true average maintenance cost and can beused as a basis for the maintenance quote.
Semiclassical calculation of ionisation rate for Rydberg helium atoms in an electric field
International Nuclear Information System (INIS)
Wang De-Hua
2011-01-01
The ionisation of Rydberg helium atoms in an electric field above the classical ionisation threshold has been examined using the semiclassical method, with particular emphasis on discussing the influence of the core scattering on the escape dynamics of electrons. The results show that the Rydberg helium atoms ionise by emitting a train of electron pulses. Unlike the case of the ionisation of Rydberg hydrogen atom in parallel electric and magnetic fields, where the pulses of the electron are caused by the external magnetic field, the pulse trains for Rydberg helium atoms are created through core scattering. Each peak in the ionisation rate corresponds to the contribution of one core-scattered combination trajectory. This fact further illustrates that the ionic core scattering leads to the chaotic property of the Rydberg helium atom in external fields. Our studies provide a simple explanation for the escape dynamics in the ionisation of nonhydrogenic atoms in external fields. (atomic and molecular physics)
On the symmetric α-stable distribution with application to symbol error rate calculations
Soury, Hamza
2016-12-24
The probability density function (PDF) of the symmetric α-stable distribution is investigated using the inverse Fourier transform of its characteristic function. For general values of the stable parameter α, it is shown that the PDF and the cumulative distribution function of the symmetric stable distribution can be expressed in terms of the Fox H function as closed-form. As an application, the probability of error of single input single output communication systems using different modulation schemes with an α-stable perturbation is studied. In more details, a generic formula is derived for generalized fading distribution, such as the extended generalized-k distribution. Later, simpler expressions of these error rates are deduced for some selected special cases and compact approximations are derived using asymptotic expansions.
First Lattice Calculation of the QED Corrections to Leptonic Decay Rates
Giusti, D.; Lubicz, V.; Tarantino, C.; Martinelli, G.; Sachrajda, C. T.; Sanfilippo, F.; Simula, S.; Tantalo, N.
2018-02-01
The leading-order electromagnetic and strong isospin-breaking corrections to the ratio of Kμ 2 and πμ 2 decay rates are evaluated for the first time on the lattice, following a method recently proposed. The lattice results are obtained using the gauge ensembles produced by the European Twisted Mass Collaboration with Nf=2 +1 +1 dynamical quarks. Systematic effects are evaluated and the impact of the quenched QED approximation is estimated. Our result for the correction to the tree-level Kμ 2/πμ 2 decay ratio is -1.22 (16 )%, to be compared to the estimate of -1.12 (21 )% based on chiral perturbation theory and adopted by the Particle Data Group.
International Nuclear Information System (INIS)
Lee, Gyeong Geun; Lee, Yong Bok; Kim, Min Chul; Kwon, Junh Yun
2012-01-01
Neutron irradiation to reactor pressure vessel (RPV) steels causes a decrease in fracture toughness and an increase in yield strength while in service. It is generally accepted that the growth of point defect cluster (PDC) and copper rich precipitate (CRP) affects radiation hardening of RPV steels. A number of models have been proposed to account for the embrittlement of RPV steels. The rate theory based modeling mathematically described the evolution of radiation induced microstructures of ferritic steels under neutron irradiation. In this work, we compared the rate theory based modeling calculation with the surveillance test results of Korean Light Water Reactors (LWRs)
International Nuclear Information System (INIS)
Stiller, W.
1985-01-01
A classical collision theory is used to describe thermal bimolecular rate coefficeints for reaction between positive and negative ions and polar molecules in a carrier gas. Special attention is paid to ion-molecule reaction in which proton transfer occurs. These reactions play an important role in terrestrial plasma devices, in ionosphere, in planetary atmospheres and in interstellar matter. The equilibrium rate coefficients of the reactions are calculated based on a microscopic reactive cross section derived from a long distance polar molecule-ion potential. The results are compared with experimental values of afterglow measurements. (D.Gy.)
International Nuclear Information System (INIS)
Jarvis, O.N.; Sadler, G.; Avery, A.; Verschuur, K.A.
1988-01-01
The gamma-radiation dose-rates inside the JET vacuum vessel due to induced radioactivity were measured at intervals throughout the 1986 period of operation, and the decay gamma energy spectrum was measured during the subsequent lengthy shutdown. The dose-rates were found to be in good agreement with values calculated using the neutron yield records compiled from the time-resolved neutron yield monitor responses for individual discharges. This result provides strong support for the reliability of the neutron yield monitor calibration. (author)
Directory of Open Access Journals (Sweden)
Vivi Endar Herawati
2015-10-01
Full Text Available Daphnia magna is a potential feed for fish. The aim of this research was to find the best treatment and effect of D. magna culture addition from fermented organic fertilizer, to growth and survival rate of Oreochromis niloticus larvae. There were five treatments, each with three repetitions used in the study. All treatments used chicken dung, and different combinations of rice bran, coconut oilcake waste and tilapia larvae. Feeding on tilapia was given by ad libitum method for five times a day until 14 days. Water quality during the research was maintained at temperature 28–29°C, DO 0.3 ppm and pH 8.1–8.2. Observed variables include relative growth rate, survival rate, food consumption rate and water quality. Our results showed that D. magna cultured by fermented organic fertilizer for tilapia larvae (O. niloticus had high significant effect (p < 0.01 on the relative growth rate and survival rate. Treatment of D. magna cultured by 1.2 g/L chicken manure, 0.9 g/L rice bran and 0.3 g/L coconut oilcake showed the highest value on the relative growth rate (10.86%; survival rate (98.46% and food consumption at first week (106.43% and second week (152.76%.
International Nuclear Information System (INIS)
Medley, S.S.; Darrow, D.S.; Roquemore, A.L.
2005-01-01
A change in the response of the neutron detectors on the National Spherical Torus Experiment occurred between the 2002-2003 and 2004 experimental run periods. An analysis of this behavior by investigating the neutron diagnostic operating conditions and comparing measured and TRANSP-calculated neutron rates is presented. Also a revised procedure for cross calibration of the neutron scintillator detectors with the fission chamber detectors was implemented that delivers good agreement amongst the measured neutron rates for all neutron detectors and all run periods. For L-mode discharges, the measured and TRANSP-calculated neutron rates now match closely for all run years. For H-mode discharges over the entire 2002-2004 period, the 2FG scintillator and fission chamber measurements match each other but imply a neutron deficit of 11.5% relative to the TRANSP-calculated neutron. The results of this report impose a modification on all of the previously used calibration factors for the entire neutron detector suite over the 2002-2004 period. A tabular summary of the new calibration factors is provided including certified calibration factors for the 2005 run
Zarrouk, Anis; Romdhane, Mohamed Salah; Espinosa, Free
2018-03-01
Patella ferruginea is the most endangered marine invertebrate of western Mediterranean rocky shores. After a study of one of its most important populations in the Zembra Archipelago National Park (Tunisia), a new protocol for the translocation of the species (size: 4-8 cm) was adopted. The first translocation was made in June 2014 in the same archipelago, where 94 specimens were moved from Zembretta to Zembra Island and marked (62 protected by cages, 20 with no cages and 60 as controls). The second translocation was performed in August 2014 (110 specimens) from Zembra to La Galite Island (185 km away). High mortality was registered during transport. The remaining individuals (39) were marked and placed in cages on the rocky shores of Galite Island, then monitored until November 2015. Growth and survival rates were measured in both translocated and control populations. The highest mortality rates were observed during the initial three days after translocation, especially for individuals with no cage protection. After a 697-day survey on Zembra Island, survival rates of 58%, 25% and 85% were observed for cage, no-cage and control populations, respectively. After a 457-day survey on La Galite Island, the survival rate was 18%. Limpets>6 cm in size had the highest survival rate among Zembra-translocated populations, whereas translocated limpets of 4-6 cm in size showed the highest survival rate in La Galite. The growth rates for both translocated populations were higher than the rate observed for controls. Our translocation experiment shows the importance of cage protection and initial limpet size for survival.