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Sample records for sunny kim phd

  1. The Ten Thousand Kims

    CERN Document Server

    Baek, Seung Ki; Kim, Beom Jun; 10.1088/1367-2630/13/7/073036

    2011-01-01

    In the Korean culture the family members are recorded in special family books. This makes it possible to follow the distribution of Korean family names far back in history. It is here shown that these name distributions are well described by a simple null model, the random group formation (RGF) model. This model makes it possible to predict how the name distributions change and these predictions are shown to be borne out. In particular, the RGF model predicts that, for married women entering a collection of family books in a certain year, the occurrence of the most common family name "Kim" should be directly proportional the total number of married women with the same proportionality constant for all the years. This prediction is also borne out to high degree. We speculate that it reflects some inherent social stability in the Korean culture. In addition, we obtain an estimate of the total population of the Korean culture down to year 500 AD, based on the RGF model and find about ten thousand Kims.

  2. The ten thousand Kims

    Science.gov (United States)

    Baek, Seung Ki; Minnhagen, Petter; Kim, Beom Jun

    2011-07-01

    In Korean culture, the names of family members are recorded in special family books. This makes it possible to follow the distribution of Korean family names far back in history. It is shown here that these name distributions are well described by a simple null model, the random group formation (RGF) model. This model makes it possible to predict how the name distributions change and these predictions are shown to be borne out. In particular, the RGF model predicts that for married women entering a collection of family books in a certain year, the occurrence of the most common family name 'Kim' should be directly proportional to the total number of married women with the same proportionality constant for all the years. This prediction is also borne out to a high degree. We speculate that it reflects some inherent social stability in the Korean culture. In addition, we obtain an estimate of the total population of the Korean culture down to the year 500 AD, based on the RGF model, and find about ten thousand Kims.

  3. Prof. Il-Hoi Kim: a tribute.

    Science.gov (United States)

    Huys, Rony

    2016-10-11

    Prof. Il-Hoi Kim was born during the Korean War on 28 February 1952 in Buan, North Jeolla Province (South Korea), near the coast of the Yellow Sea whose tidal flats would become one of his favourite sampling grounds during his scientific career. From an early age he developed an intense interest in natural history in general and marine biology in particular. He obtained his B.Sc. in 1974 at the Department of Biology Education, Gongju National College of Education. Between 1974 and 1976 he was conscripted into the South Korean military during which he progressed to the rank of lieutenant of artillery in the Reserve Officers' Training Corps (ROTC). After his graduation in 1980 at the Department of Zoology, Seoul National University, Il-Hoi Kim moved to the Department of Biology, Gangneung-Wonju National University on the East Sea coast where he was first appointed lecturer (1981) before taking up the position of assistant professor (1983), associate professor (1987) and full professor (1993). In 1985 he had previously completed his Ph.D. dissertation on Korean barnacles at Seoul National University under the supervision of the late Prof. Hoon Soo Kim, a pioneer in marine invertebrate taxonomy and renowned as the father of carcinology in Korea.

  4. A Sunny Boy——Ethan Ruan

    Institute of Scientific and Technical Information of China (English)

    李成民

    2011-01-01

    He is not perfect. He wasn’t a good student and he is not the most handsome boy around.But Taiwanese actor Ethan Ruan(阮经天)has his own charm (魅力):he is sporty; he is sunny;he works hard.

  5. Organ transplantation: A Sunni Islamic perspective

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    Mohammed Albar

    2012-01-01

    Full Text Available This paper reviews the standpoints of Muslim jurists within the Sunni tradition on organ transplantation. Muslim jurists allowed different forms of bone grafts (autograft, allograft and xenograft for widely broken bones. Ibn Sina in 1037 discussed this subject in Al-Kanoon 1000 years ago. In 1959, the Muftis of Egypt and Tunisia allowed, under specific conditions, corneal transplants from dead persons. Thereafter, many fatwas (jurisprudence on organ trans-plantation have been issued from different parts of the Muslim world. In Amman, Jordan, the International Islamic Jurist Council recognized brain-death as a recognized sign of death in Islam in October 1986. This paved the way for organ transplantation from brain-dead persons, which started immediately in Saudi Arabia. In 1990 and 2003, the International Islamic Fiqh Academy (IIFA and the Islamic Fiqh Academy (IFA issued important fatwas on organ transplantation. By the end of 2008, more than 3600 organs were transplanted from brain-dead persons in Saudi Arabia.

  6. An explicit construction of sunny nonexpansive retractions in Banach spaces

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    Simeon Reich

    2005-10-01

    Full Text Available An explicit algorithmic scheme for constructing the unique sunny nonexpansive retraction onto the common fixed point set of a nonlinear semigroup of nonexpansive mappings in a Banach space is analyzed and a proof of convergence is given.

  7. The Specter of Sunni Military Mobilization in Lebanon

    Science.gov (United States)

    2013-11-01

    2013. 41 Syria Regional Refugee Response, UNHCR , accessed November 12, 2013, http://data.unhcr.org/syrianrefugees/regional.php. 16 increasingly...categories of Sunni militants in Lebanon: those with roots in the refugee Palestinian communities, and those with roots in the international Salafi...of civil war in 1975. The roughly 300,000 Palestinians living in refugee camps are overwhelmingly Sunni.3 Since the heyday of the Palestinian

  8. Dissimulation in Sunni Islam and Morisco Taqiyya

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    Stewart, Devin

    2013-12-01

    Full Text Available This study provides an outline of the religious doctrine of taqiyya or dissimulation in Sunni Islam, drawing on Qur’ānic commentaries, hadīth compilations, legal manuals, and ethical treatises. Moriscos and the North African jurists who advised them had access to discussions of taqiyya and the closely connected legal dispensation of coercion (ikrāh through these sources, many of which were wellknown in al-Andalus before the Reconquista, and some of which continued to be popular afterwards. Attention to this material helps one to interpret the 1504 fatwā of Ibn Abī Jum’a al-Wahrānī to the Moriscos and in particular his discussion of blasphemy under coercion.Este trabajo ofrece un resumen de la doctrina religiosa de taqiyya o disimulación en el islam sunní, recurriendo a comentarios del Qur’ān, compendios de ḥadīṯ, obras de ley islámica y tratados de principios éticos. En las fuentes andaluces antes de la conquista cristiana aparecen discusiones acerca del concepto de taqiyya y del de coerción (ikrāh, ambos exenciones legales, y algunas de ellas continuaron estando a disposición de los moriscos y de los juristas norteafricanos que les aconsejaban. El análisis de estos materiales facilita la interpretación de la fatwā que Ibn Abī Ȳum’a al-Wahrānī envió a los moriscos en el ano 1504 y particularmente la comprensión de su tratamiento de la blasfemia bajo coacción.

  9. On the Methodology of Research of Sunni-Shiite Relations

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    Olga Sergeevna Chikrizova

    2015-12-01

    Full Text Available The article is devoted to methodological aspects of analysis of confrontation between two biggest trends in Islam - Sunnism and Shiism. It’s extremely important to study Sunni-Shiite relations on the modern stage because they reflect geopolitical and geostrategic rivalry in the region and change of interstate alliances’ configuration. After “the Arab spring” in the Middle East some conflicts have flared up (Iraq, Syria, Yemen, and one of the reasons of all the conflicts is a confrontation between Sunnis and Shiites. Moreover, some more hot spots are brewing, in which the representatives of two major trends in Islam will face (Lebanon, Saudi Arabia, Bahrain. In order to find ways to settle these conflicts we need to learn profoundly the origins, nature and characteristics of Sunni-Shiite relations, and it also determines the relevance of this article’s topic. Using comparative method, historicism, problem-chronological method and quantitative methods of analysis, the author indicates six periods of Sunni-Shiite antagonism, during which the contradictions between two trends had gradually shifted from domestic to international level, and then to global level. Comparing foreign policy practice of Sunni and Shiite states at the present stage, the author proves that nowadays the struggle between Sunnis and Shiites for the implementation of models of the Islamic world’s development takes place. These models are global, they are aimed at the unification of the Islamic world. However they are based on completely different visions of this world’s configuration, particularly in the region of the Middle East.

  10. PEMIKIRAN ISLAM DALAM PERSPEKTIF SUNNI DAN SYI’AH

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    Muh. Shohibul Itmam

    2013-09-01

    Full Text Available THE ISLAMIC THINKING IN SUNNI AND SYI’AH PERSPECTIVES. This paper attempts to describe the problems associated with Islam in particular with regard to Sunni and Syi’ah teachings. The number of  streams that developed in Islam today has resulted Islam got claims from various clerical community, such as terrorism and others, resulting in the ruination image of  Islam in the constellation of  the religions of  man. As the flow and the teachings of  the most dominating civilization of  the world religions, Sunni and Syiah, including the Wahhabi, are necessary to clarify the existence or clarified the diversity in the constellation of  Islam, considering the number of streams that are currently claiming truth on themselves. Iran as the country becoming a reference in the world of  developing Syi’ah should be used as a reference in the study of  understanding associated with Sunni and Syi’ah. From this country, the world of  Islam knows the concept ofgoverning “Wilayatul Faqih”. The concept was pioneered by the government of Imam Khomeini who became known after Islamic Revolution in Iran 1979 and continues to be developed up to now. Every year Iran is celebrated with a huge demonstration with the slogan in Persian, “Islam Pyruz ast, ast Nabud Istikbar”, Islam is victorious, crushed the vanity of the islam enemy. keywords: Islam, Sunni, Syi’ah, Perspective, Differences, Similarities. Tulisan ini mencoba mengurai persoalan yang berhubungan dengan Islam secara khusus yang berkaitan dengan ajaran Sunni dan Syi’ah. Banyaknya aliran yang berkembang dalam Islam dewasa ini telah mengakibatkan Islam mendapat klaim dari berbagai komunitas agamawan, seperti teroris dan lainnya, yang mengakibatkan redupnya citra Islam dalam percaturan agama-agama manusia. Sebagai aliran dan ajaran yang paling mendominasi peradaban agama dunia, Sunni dan  Syi’ah,  termasuk  Wahabi,  perlu  memperjelas  eksistensinya atau diperjelas

  11. The Sunni Spring: Counter-Attack in the War for Islamic Civilization

    Science.gov (United States)

    2012-12-06

    and the Arab Spring is a continuation of this civilizational crisis. To reconcile the rise of exclusivist Sunni Islamism in the Middle East and...variety of subtle differences from Sunni Islam and the Salafist does not fail to notice them. Salafis are exclusivists . Those who do not share their

  12. Kim Dotcomi kättemaks / Andy Greenberg

    Index Scriptorium Estoniae

    Greenberg, Andy

    2013-01-01

    Skandaalne Internetimagnaat Kim Schmitz, rohkem tuntud kui Kim Dotcom, on veendunud, et tema loodud failivahetusprogrammi Megauploadi mahavõtmisega ja autoriõiguste rikkumise süüdistusega tehti talle liiga ning ta on asunud raevukalt vastulöögile USA valitsuse vastu

  13. Kim Dotcomi kättemaks / Andy Greenberg

    Index Scriptorium Estoniae

    Greenberg, Andy

    2013-01-01

    Skandaalne Internetimagnaat Kim Schmitz, rohkem tuntud kui Kim Dotcom, on veendunud, et tema loodud failivahetusprogrammi Megauploadi mahavõtmisega ja autoriõiguste rikkumise süüdistusega tehti talle liiga ning ta on asunud raevukalt vastulöögile USA valitsuse vastu

  14. Insoo Kim Berg and Solution-Focused Therapy.

    Science.gov (United States)

    West, John D.; Bubenzer, Donald L.; Smith, Jeffrey M.; Hamm, Terri L.

    1997-01-01

    Interview with Insoo Kim Berg, a leading theoretician in solution-based therapy. She is joined by Steve de Shazer, a colleague. They discuss the evolution of her work and its application to various populations. (MKA)

  15. Ambient bioaerosol particle dynamics observed during haze and sunny days in Beijing.

    Science.gov (United States)

    Wei, Kai; Zou, Zhuanglei; Zheng, Yunhao; Li, Jing; Shen, Fangxia; Wu, Chang-Yu; Wu, Yusheng; Hu, Min; Yao, Maosheng

    2016-04-15

    The chemical characteristics of airborne particulate matter (PM) have been extensively studied; however, little information exists for its biological components (bioaerosol) especially during a haze event in mega cities. Herein, we studied the bioaerosol (fluorescent particle) dynamics on both haze and sunny days in Beijing from Dec. 2013 to March 2014 by employing a widely used real-time bioaerosol sensor-ultraviolet aerodynamic particle spectrometer (UV-APS). Firstly, we studied the fluorescent particle (BioPM) concentration and size distributions during three independent haze and three independent sunny days. Secondly, we investigated BioPM dynamics over a two-week long monitoring period which included consecutive haze days and alternated sunny days. In addition, we analyzed bacterial community structures and endotoxin levels in the air samples using pyrosequencing and Limulus amebocyte lysate (LAL) method, respectively. More than 6-fold higher fluorescent particle concentrations up to 5×10(5)/m(3) with peaks at night or early dawn were detected at the time of haze occurrences than those observed on sunny days. When the haze episode progressed for 3-5days, the BioPM concentrations were observed to decrease to the levels that were typically observed on sunny days. In general, ozone levels were found to be elevated at noon, while BioPM, NOx and relative humidity were reduced. Gene sequence analysis revealed no significant difference in abundances and community structures for top 13 bacterial genera between haze and sunny days, yet about twice higher endotoxin levels (12.4EU/m(3)) were detected on haze days than on sunny days. The results here facilitate a better understanding of atmospheric fluorescent particle dynamics including those under haze events.

  16. Coenite seiklused ja Kim Ki-duki huumor / Merit Kask

    Index Scriptorium Estoniae

    Kask, Merit

    2007-01-01

    60-nda Cannes'i filmifestivali filme : Ethan ja Joel Coen'i "Pole maad vanadele meestele" ("No Country for Old Men" ; Ameerika Ühendriigid), Kim Ki-duki "Hingetõmme" ("Soom"/"Breath" ; Lõuna-Korea) ja Raphael Nadjari "Tehilim" (Prantsusmaa - Iisrael - Ameerika Ühendriigid)

  17. Prikljutshenija Koenov i jumor Kim Ki-duka / Merit Kask

    Index Scriptorium Estoniae

    Kask, Merit

    2007-01-01

    60-nda Cannes'i filmifestivali filme : Ethan ja Joel Coen'i "Pole maad vanadele meestele" ("No Country for Old Men" ; Ameerika Ühendriigid), Kim Ki-duki "Hingetõmme" ("Soom"/"Breath" ; Lõuna-Korea) ja Raphael Nadjari "Tehilim" (Prantsusmaa - Iisrael - Ameerika Ühendriigid)

  18. Coenite seiklused ja Kim Ki-duki huumor / Merit Kask

    Index Scriptorium Estoniae

    Kask, Merit

    2007-01-01

    60-nda Cannes'i filmifestivali filme : Ethan ja Joel Coen'i "Pole maad vanadele meestele" ("No Country for Old Men" ; Ameerika Ühendriigid), Kim Ki-duki "Hingetõmme" ("Soom"/"Breath" ; Lõuna-Korea) ja Raphael Nadjari "Tehilim" (Prantsusmaa - Iisrael - Ameerika Ühendriigid)

  19. Prikljutshenija Koenov i jumor Kim Ki-duka / Merit Kask

    Index Scriptorium Estoniae

    Kask, Merit

    2007-01-01

    60-nda Cannes'i filmifestivali filme : Ethan ja Joel Coen'i "Pole maad vanadele meestele" ("No Country for Old Men" ; Ameerika Ühendriigid), Kim Ki-duki "Hingetõmme" ("Soom"/"Breath" ; Lõuna-Korea) ja Raphael Nadjari "Tehilim" (Prantsusmaa - Iisrael - Ameerika Ühendriigid)

  20. Semantic Annotation Framework For Intelligent Information Retrieval Using KIM Architecture

    Directory of Open Access Journals (Sweden)

    Sanjay Kumar Malik

    2010-11-01

    Full Text Available Due to the explosion of information/knowledge on the web and wide use of search engines for desiredinformation,the role of knowledge management(KM is becoming more significant in an organization.Knowledge Management in an Organization is used to create ,capture, store, share, retrieve and manageinformation efficiently. The semantic web, an intelligent and meaningful web, tend to provide a promisingplatform for knowledge management systems and vice versa, since they have the potential to give eachother the real substance for machine-understandable web resources which in turn will lead to anintelligent, meaningful and efficient information retrieval on web. Today,the challenge for web communityis to integrate the distributed heterogeneous resources on web with an objective of an intelligent webenvironment focusing on data semantics and user requirements. Semantic Annotation(SA is being widelyused which is about assigning to the entities in the text and links to their semantic descriptions. Varioustools like KIM, Amaya etc may be used for semantic Annotation.In this paper, we introduce semantic annotation as one of the key technology in an intelligent webenvironment , then revisit and review, discuss and explore about Knowledge Management and SemanticAnnotation. A Knowledge Management Framework and a Framework for Semantic Annotation andSemantic Search with Knowledge Base(GATE and Ontology have been presented. Then KIM Annotationplatform architecture including KIM Ontology(KIMO, KIM Knowledge Base and KIM front ends havebeen highlighted. Finally, intelligent pattern search and concerned GATE framework with a KIMAnnotation Example have been illiustrated towards an intelligent information retrieval

  1. PhD Dissertations

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2003-12-01

    Full Text Available Report of PhD Dissertations. Guido Antonioli Conservator pacis et iustitie. La signoria di Taddeo Pepoli a Bologna (1337-1347, Tesi di dottorato di ricerca in Filologia romanza e cultura medievale (XIII ciclo, Università degli Studi di Bologna, 2001   Elisabetta Filippini «In vassallatico episcopi permanere debent». Rapporti vassallatici e concessioni beneficiali dei vescovi di Cremona fra X e XIII secolo, Tesi di dottorato di Ricerca in Storia Medievale (XV ciclo, Università Cattolica del Sacro Cuore di Milano, 2003   Marco Meschini, Innocenzo III e il "negotium pacis et fidei" in Linguadoca tra il 1198 e il 1215, Tesi di dottorato di ricerca in Storia medievale, Università Cattolica del Sacro Cuore, 2003   Fabrizio Ricciardelli The Politics of Exclusion in Florence (1215-1434, thesis submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy in History, University of Warwick, Department of History, April 2003 Renata Salvarani Baptizare pueros et decimas dare. Cura delle anime, strutturazione ecclesiastica e organizzazione delle campagne in area gardesana fra VIII e XIII secolo (diocesi di Brescia, Verona, Mantova e Trento, Tesi di dottorato in Storia medievale (XV ciclo, Università Cattolica del Sacro Cuore di Milano, 2002-2003   Vito Sibilio Le parole della prima crociata, Tesi di dottorato di ricerca in Storia dei centri delle vie e della cultura dei pellegrinaggi nel medioevo euromediterraneo, Università degli studi di Lecce, 2003

  2. PhD Dissertations

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2000-06-01

    Full Text Available Report of PhD Dissertations.   Miguel Calleja Puerta El conde Suero Vermúdez, su parentela y su entorno social. La aristocracia leonesa en los siglos XI y XII, Tesis de doctorado en Historia, Universidad de Oviedo (España, 2000   Adele Cilento Potere e monachesimo nella Calabria bizantina: relazioni e interferenze (secc. IX-XI, Tesi di dottorato di ricerca in Storia medievale (X ciclo, Università degli Studi di Torino, 2000   Amedeo De Vincentiis Firenze e i signori. Sperimentazioni istituzionali e modelli di regime nelle signorie fiorentine degli Angioini (fine XIII - metà XIV secolo, Tesi di dottorato di ricerca in Storia medioevale (XI ciclo, Università degli Studi di Milano, 1999   Marco Folin Il sistema politico di un antico Stato italiano: i ducati estensi nella prima Età moderna (1452-1598, Tesi di dottorato di ricerca in Storia, Scuola Normale superiore di Pisa, 2000   Barbara Frale Guardiani del Santuario. Le radici orientali del processo contro l’ordine del Tempio (1128 - 1314, Tesi di dottorato di ricerca in Storia sociale d’Europa (XI ciclo, Università "Ca’ Foscari" di Venezia, 2000

  3. PhD Dissertations

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2003-06-01

    Full Text Available Reporto of PhD Dissertations.   Mario Dalle Carbonare Società, potere e clientele nell’Irlanda altomedievale (secoli V-IX, Tesi di dottorato di ricerca in Storia sociale europea, Università "Ca' Foscari" di Venezia, 2003 Vieri Mazzoni La legislazione antighibellina e la politica oligarchica della Parte Guelfa di Firenze nel secondo Trecento (1347-1378, Tesi di dottorato di ricerca in Storia Medievale (ciclo XII, Università degli Studi di Firenze   Alma Poloni Pisa dalle origini del movimento popolare alla discesa di Ludovico il Bavaro. I gruppi dirigenti cittadini tra continuità e trasformazione, Tesi di dottorato di ricerca in Storia dell'Europa nel medioevo, Università degli studi di Pisa, 2003   Andrea Puglia Potere marchionale, amministrazione del territorio, società locali dalla morte di Ugo di Tuscia a Guelfo VI di Baviera (1001-1160, Tesi di dottorato di ricerca in Storia medievale, Università degli studi di Milano, 2003

  4. PhD Dissertations

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2010-06-01

    Full Text Available Report of PhD dissertations. Andrea Brugnoli Una storia locale: l’organizzazione del territorio veronese nel medioevo: trasformazioni della realtà e schemi notarili (IX-metà XII secolo, Tesi di dottorato di ricerca in Scienze Storiche e Antropologiche (XXII ciclo, Università degli Studi di Verona, 2010   Luca Filangieri Famiglie e gruppi dirigenti a Genova (secoli XII-metà XIII, Tesi di dottorato di ricerca in Storia medievale (XXII ciclo, Università degli Studi di Firenze, 2010   Jakub Kujawi ski Wernakularna kolekcja historiograficzna z rękopisu francuskiego nr 688 z Biblioteki Narodowej w Paryżu. Studium źródłoznawcze (La raccolta dei volgarizzamenti delle opere storiografiche nel manoscritto francese 688 della Biblioteca Nazionale di Parigi, Tesi di dottorato, Università “Adam Mickiewicz”, Facoltà di Storia, Pozna, a.a. 2009/2010   Marta Longhi I signori “de Radicata”. Strategie di affermazione familiare e patrimoniale nel Piemonte dei secoli XII-XIV, Tesi di dottorato di ricerca in Istituzioni, Società, Religioni dal Tardo Antico alla fine del Medioevo (XX ciclo, Università di Torino, 2008

  5. PhD Dissertations

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2004-06-01

    Full Text Available Report of PhD Dissertations. Francesco Barone Istituzioni, società ed economia a Catania nel tardo medioevo (XIV-XV secolo, Tesi di dottorato in Storia medievale (XVI ciclo, Università degli Studi di Firenze, 2004   Laura Berti Ceroni Il territorio e le strutture di Cesarea e Classe tra tarda antichità e alto medioevo in rapporto con Ravenna, Tesi di dottorato di ricerca in Storia e Informatica, Università degli studi di Bologna, 2002-2003.   Marco Bicchierai Poppi dalla signoria dei conti Guidi al vicariato del Casentino (1360-1480, Tesi di dottorato in Storia medievale (XIV ciclo, Università degli Studi di Firenze, 2004   Emanuela Garimberti Spatiosa ad habitandum loca. Luoghi e identità nella Historia Langobardorum di Paolo Diacono, Tesi di dottorato in Storia medievale (XV ciclo, Università degli Studi di Bologna, 2004   Lorenzo Tanzini Sistemi normativi e pratiche istituzionali a Firenze dalla fine del XIII all’inizio del XV secolo, Tesi di dottorato di ricerca in Storia medievale (XVI ciclo, Università degli Studi di Firenze, 2004   Stefania Tarquini Pellegrinaggio e asseto urbano di Roma, Tesi di dottorato di ricerca in Storia dei centri, delle vie e della cultura dei pellegrinaggi nel Medioevo euro mediterraneo (XV ciclo, Università degli studi di Lecce, 2003

  6. Status of the KIMS-NaI experiment

    CERN Document Server

    Kim, Kyungwon

    2015-01-01

    KIMS-NaI is a direct detection experiment searching for Weakly Interacting Massive Particles (WIMP) via their scattering off of nuclei in a NaI(Tl) crystal. The KIMS-NaI collaboration has carried out tests of six crystals in the Yangyang underground laboratory in order to develope low-background NaI(Tl) crystals. Studies of internal backgrounds crystals have been performed with the goal of reducing backgrounds levels to 1 dru at 2 keV. Pulse shape discrimination (PSD) capabilities were also investigated for distinguishing between WIMP nuclear recoil signals and electron recoil backgrounds. The PSD analysis was applied to underground data with one low background NaI(Tl) detector and the evaluation of WIMP mass limit is ongoing.

  7. Verification of tropical cyclone using the KIAPS Integration Model (KIM)

    Science.gov (United States)

    Lim, S.; Seol, K. H.

    2015-12-01

    The Korea Institute of Atmospheric Prediction Systems (KIAPS) is a government funded non-profit research and development institute located in Seoul, South Korea. KIAPS is developing the Global Model, a backbone for the next-generation operational global numerical weather prediction (NWP) system with three-phase plans; Establishment and R&D Planning (2011-2013), Test Model Development (2014-2016), and Operational Model Development (2017-2019). As a second-phase, we have beta version of KIAPS Integration Model (KIM) that can produce reasonable global forecasting. Using the KIM model, we are evaluating the tropical cyclone forecast in the global model. To objectively provide a best estimate of the storm's central position, we use the Geophysical Fluid Dynamics Laboratory (GFDL) vortex tracker, widely used in tracker algorithms. It gives the track and intensity of the storm throughout the duration of the forecast based on its algorithm. As a verification tool, we use the Model Evaluation Tool - Tropical Cyclone (MET-TC), which produces statistical evaluation. We expect these results give the statue of ability for the tropical cyclone forecast with KIM model.

  8. Perspektif Kim Knott tentang Insider-Outsider dalam Studi Agama

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    Sujiat Zubaidi Saleh

    2016-03-01

    Full Text Available Contemporary discourse of religious studies indicates many fields of study in understanding religion. Religious spectrum not only relates with credo, faith, worldview, theology and etcetera but expanding in various aspect (cultural and historical side. The cultural and historical aspects in a certain point give some problems in academic field. Kim Knott based on those matters tries to give a new shot in analyzing religion based on the issued aspects. Looking at how complicated is it Kim Knott maps it into two religious approaches. First is the hardship situation to make such a clear gap between religious and not-religious territory and second is the complicated problem in relation with religion as tradition and religion as faith. This article elucidates a viewpoint of Kim Knott as a “new outline” on religious studies. Knott attempts to eliminate the subjective intentions by using two basic perspectives of methodology: insider and outsider. He has classified the concept of inter-connection between social and religious role into four elements: pure participant, researcher as participant, participant as researcher and pure researcher. However, this concept remains an important problem concerning to standard of objectivity. Knott’s approach tries to place researcher on the margin of appreciation as a border line between insider-outsider.

  9. 'Defending our honour': Authenticity and the framing of resistance in the Iraqi Sunni town of Falluja

    NARCIS (Netherlands)

    Meijer, R.

    2004-01-01

    In April 2004 a revolt broke out against the American occupation in the Iraqi Sunni town of Falluja. Besides a military confrontation, it was also a war of words how to conceptualise the clash of interests and values of the indigenous population in opposition to those of the American occupation. At

  10. An Interview with Sunny Hansen: Pioneer and Innovator in Counseling and Career Development

    Science.gov (United States)

    Skovholt, Thomas S.; Hage, Sally M.; Kachgal, Mera M.; Gama, Elizabeth Pinheiro

    2007-01-01

    During her 45-year career, Sunny Hansen was a pioneer and innovator in counseling and career development. She has lived the holistic life about which she writes and teaches. In this interview, she discussed the major influences on her life, the evolution of her professional career from English and journalism teacher to counselor and counselor…

  11. Multilingual Language and Literacy Practices and Social Identities in Sunni Madrassahs in Mauritius: A Case Study

    Science.gov (United States)

    Owodally, Ambarin Mooznah Auleear

    2011-01-01

    This study analyzes the connections among multilingual language practices, multilingual literacy practices, and social identities in two Sunni madrassahs in Mauritius. The study is framed by sociolinguistic and poststructuralist perspectives on language and identity, and social practice views of literacy. Data collection and analysis involved…

  12. Sunni Islam: What Students Need to Know. Footnotes. Volume 15, Number 1

    Science.gov (United States)

    Calvert, John

    2010-01-01

    It is the mark of a great world religion to accommodate different outlooks and sensibilities. Quite often, these differences are manifested in terms of formal divisions within the faith. In Islam, the major split is between Sunni and the various forms of Shiism, though other divisions also exist. This essay, excerpted from the book "Divisions…

  13. Industrial PhD report: Sustainable Innovation

    DEFF Research Database (Denmark)

    Olesen, Gitte Gylling Hammershøj

    2011-01-01

    Erhvervs PhD rapport udarbejdet i tilknytning til Erhvervs PhD kurset der er obligatorisk for Erhvervs PhD studerende. Rapporten omhandler relationer melllem den akademiske verden og industrien i sammenhæng med PhD projektet, betragtet og analyseret gennem teori om bæredygtig innovation....

  14. Industrial PhD report: Sustainable Innovation

    DEFF Research Database (Denmark)

    Olesen, Gitte Gylling Hammershøj

    2011-01-01

    Erhvervs PhD rapport udarbejdet i tilknytning til Erhvervs PhD kurset der er obligatorisk for Erhvervs PhD studerende. Rapporten omhandler relationer melllem den akademiske verden og industrien i sammenhæng med PhD projektet, betragtet og analyseret gennem teori om bæredygtig innovation....

  15. Enesekaitsesituatsioonides vahetu sunni kasutamine vanglas. Karistusõiguslik ja haldusõiguslik analüüs / Anneli Soo, Kaidi Tarros

    Index Scriptorium Estoniae

    Soo, Anneli, 1984-

    2015-01-01

    Vanglaametniku poolt vahetu sunni kasutamisest enese või teise isiku kaitseks. Vahetu sunni kasutamise nõuetest vangistusõiguses, vanglaamentiku vastutuse välistamise tingimustest karistusseadustiku (KarS) alusel ning distsiplinaarvastutusest ja riigivastutusest. Asjakohasest kohtupraktikast

  16. Enesekaitsesituatsioonides vahetu sunni kasutamine vanglas. Karistusõiguslik ja haldusõiguslik analüüs / Anneli Soo, Kaidi Tarros

    Index Scriptorium Estoniae

    Soo, Anneli, 1984-

    2015-01-01

    Vanglaametniku poolt vahetu sunni kasutamisest enese või teise isiku kaitseks. Vahetu sunni kasutamise nõuetest vangistusõiguses, vanglaamentiku vastutuse välistamise tingimustest karistusseadustiku (KarS) alusel ning distsiplinaarvastutusest ja riigivastutusest. Asjakohasest kohtupraktikast

  17. PhD Dissertations

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2005-06-01

    Full Text Available Report of PhD Dissertations. Federica Cengarle Le investiture feudali di Filippo Maria Visconti (1412-1447, Tesi di dottorato di ricerca in Storia medievale, Università degli Studi di Milano, 2005 Silvia Coazzin Liberi domini totius castri. L'aristocrazia rurale "minore" nel Senese e nella Toscana meridionale. Forme di egemonia, assetto sociale e patrimoniale di lignaggi, famiglie e gruppi consortili di castello (secc. XI-XIV, Tesi di dottorato di ricerca in Storia medievale, Università degli studi di Firenze, 2005 Maria Elena Cortese Signori e castelli. Famiglie aristocratiche, dominati signorili e trasformazioni insediative nel comitatus fiorentino (fine X-metà XII secolo, Tesi di dottorato di ricerca in Storia medievale, Università degli studi di Firenze, 2005 Patrizia Meli Gabriele Malaspina marchese di Fosdinovo: il condottiero ed il politico, Tesi di dottorato di ricerca in Storia medievale, Università degli studi di Firenze, 2005 Federica Pessotto La Morea franca. Economia e istituzioni tra Oriente e Occidente nei secoli XIII e XIV, Tesi di dottorato di ricerca in Istituzioni, Società e Religioni dal Tardoantico alla fine del Medioevo, Università degli studi di Torino, 2003 Lorenzo Pubblici Dal Caucaso al Mar d’Azov. L’impatto dell’invasione mongola nella Caucasia fra nomadismo e civiltà sedentaria (1204-1395, Tesi di dottorato di ricerca in Storia medievale, Università degli studi di Firenze, 2005 [01/05] Riccardo Rao "Comunia". Risorse collettive e patrimoniali dei maggiori comuni subalpini (secoli XII - inizio XIV, Tesi di dottorato di ricerca in Storia medioevale, Università degli Studi di Milano, 2005 Alessandro Soddu Feudalesimo e potere signorile in Sardegna nei secoli XI-XIV.  La signoria territoriale dei Malaspina, Tesi di dottorato di ricerca in Storia, Università "Pompeu Fabra" di Barcellona, 2004

  18. PhD Dissertations

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2002-06-01

    Full Text Available Report of PhD dissertation. Laura Baietto Una politica per le città. Rapporti fra papato, vescovi e comuni nell'Italia centro-settentrionale da Innocenzo III a Gregorio IX, Tesi di dottorato di ricerca in Storia Medievale, Università degli Studi di Torino, 2002   Giuseppe Banfo Compresenze e sovrapposizioni di poteri territoriali di qualità diversa tra X e XIII: il caso del basso Monferrato, Tesi di dottorato di ricerca in Storia medievale, Università degli Studi di Torino, 2002   Francesca Dell'Acqua La vetrata tra l'età tardo imperiale e l'altomedioevo: le fonti, l'archeologia, Tesi di Perfezionamento in Storia dell'Arte Medievale, Scuola Normale Superiore di Pisa, 2001   Primo Giovanni Embriaco I vescovi di Albenga e gli sviluppi signorili nella Liguria occidentale (secoli XI-XIII, Tesi di dottorato di ricerca in Storia medievale, Università degli Studi di Torino, 2001   Antonella Ghignoli Documenti e proprietà altomedievali. Fondamenti e problemi dell'esegesi storica delle fonti documentarie nello specchio della tradizione delle carte pisane dei secoli VIII-XI, Tesi di dottorato di ricerca in Storia medievale, Università degli Studi di Firenze, 2002   Vito Loré Espansione monastica e mutamenti politici. La Trinità di Cava nei suoi rapporti con i sovrani longobardi e normanni e con l'aristocrazia territoriale. Secoli XI-XII, Tesi di dottorato di ricerca in Storia medievale, Università degli Studi di Firenze, 2002   Rosaria Stracuzzi Messina nel '400, Tesi di dottorato di ricerca in Storia medievale, Università degli Studi di Palermo, 2001   Stefania Tamburini Le "portate" ecclesiastiche nel piviere di San Giovanni in Firenze nel 1427. Spunti per una riflessione sul patrimonio ecclesiastico della diocesi fiorentina,Tesi di dottorato di ricerca in Storia e informatica, Università degli Studi di Bologna, 2001

  19. Anmeldelse af Kim Wind Andersen: Overblik over selskabers underskudsfremførsel

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2011-01-01

    Artiklen anmelder Kim Wind Andersen: Overblik over selskabers underskudsfremførsel (Thomson Reuters Professional, 2010)......Artiklen anmelder Kim Wind Andersen: Overblik over selskabers underskudsfremførsel (Thomson Reuters Professional, 2010)...

  20. PhD Dissertations

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2004-12-01

    Full Text Available Report of PhD Dissertations. Massimo Della Misericordia Divenire comunità. Comuni rurali, poteri signorili, identità sociali in Valtellina e nella montagna lombarda nel tardo medioevo, Tesi di dottorato in Storia medievale (XIV ciclo, Università degli Studi di Torino, 2003   Mariano Dell’Omo Il monastero di S. Liberatore alla Maiella centro dell’irradiazione di Montecassino nell’Abruzzo medievale e moderno. Contributo alla storia dell’organizzazione patrimoniale e della civiltà monastica cassinese nell’Italia centrale attraverso i documenti di S. Liberatore conservati nell’Archivio di Montecassino. Introduzione storica, paleografica e archivistica. Edizione dei documenti più antichi (†798-1000 e regesti di quelli posteriori (1005-1735, Tesi di dottorato in Storia Ecclesiastica, Facoltà di Storia Ecclesiastica, Pontificia Università Gregoriana di Roma,  2004   Giulia Lorenzoni Conquistare e governare la città. Forme di potere e istituzioni nel primo anno della signoria viscontea a Bologna (ottobre 1350-novembre 1351, Tesi di dottorato in Storia medievale (XVI ciclo, Università degli Studi di Bologna, 2004   Federica Monteleone Il viaggio di Carlo Magno in Terra Santa. Un’esperienza di pellegrinaggio nella tradizione europea occidentale, Tesi di dottorato di ricerca in Storia dei centri, delle vie e della cultura dei pellegrinaggi nel Medioevo euro mediterraneo (XV ciclo   Francesca Pucci Donati Fra teorie mediche e pratica quotidiana: i calendari dietetici dell’Occidente latino altomedievale (secoli IX-XI, Tesi di dottorato di ricerca in Storia medievale (XV ciclo, Università degli studi di Bologna, 2004 Alberto Ricciardi L’Epistolario di Lupo di Ferrières come fonte per la storia degli intellettuali nell’età di Carlo il Calvo, Tesi di dottorato in Storia medievale (XV ciclo, Università degli Studi di Bologna, 2004   Francesco Paolo Terlizzi I trattati dell'Anonimo Normanno: ricerche di ecclesiologia, Tesi

  1. Chang Sei Kim's Activities on Public Health in Colonial Korea

    Directory of Open Access Journals (Sweden)

    Park Yunjae

    2006-12-01

    Full Text Available After graduating from Severance Medical College in 1916, Chang Sei Kim went to Shanghai to work as a missionary in a adventist hospital. The establishment of the Korean Provisional Government led him to participate in the independence movement. Educating nurses to assist the forthcoming war for independence, he seemed to realize the fact that the health of Koreans would be a key factor for achieving independence. He left for the U.S. to conduct comprehensive research on medicine. Chang Sei Kim was the first Korean to receive a Ph. D. degree of Public Health, graduating from the Johns Hopkins School of Hygiene and Public Health in 1925. He then gained an opportunity to work for Korea as a professor at Severance Medical College. His objective was the 'Reconstruction of the Korean People In Terms of Physical Constitution.' He pointed out that Koreans' weak state of health was a major reason for Korea's colonization. To gain independence, he emphasized that the Korean people should receive education on public health in order to improve the primitive conditions of sanitation. There is little doubt that Chang Sei Kim's ideas developed Heungsadan's views on medicine in terms of its stress on cultivation of ability, especially considering the fact that he was a member of the organization. As a member of the colonized who could not participate in the developing official policy, Chang Sei Kim was not able to implement his ideas fully, because an individual or a private organization could not carry out policy on public health as large a scale as the government did. Never giving up his hopes for Korean independence, he rejected requests to assume official posts in the Government-General. That was why he was particularly interested in the Self-Governing Movement in 1920s Korea. If the movement had attained its goal, he might have worked for the enhancement of sanitary environment as a director of Sanitary Department. His application for funding to establish

  2. Tubular kidney injury molecule-1 (KIM-1) in human renal disease

    NARCIS (Netherlands)

    van Timmeren, M. M.; van den Heuvel, M. C.; Bailly, V.; Bakker, S. J. L.; van Goor, H.; Stegeman, C. A.

    2007-01-01

    KIM-1, a transmembrane tubular protein with unknown function, is undetectable in normal kidneys, but is markedly induced in experimental renal injury. The KIM-1 ectodomain is cleaved, detectable in urine, and reflects renal damage. KIM-1 expression in human renal biopsies and its correlation with ur

  3. Kim C. Sturgess. Shakespeare and the American Nation.

    Directory of Open Access Journals (Sweden)

    Jean‑Louis Claret

    2006-04-01

    Full Text Available The front page of Kim C Sturgess’s recent book entitled Shakespeare and the American Nation is particularly mind‑teasing insofar as it represents the famous Droeshout engraving of the bard (it illustrated the front‑page of the 1623 edition of Shakespeare’s works standing out against a background that superimposes the head of the Statue of Liberty on the spangled banner. The starting point of Sturgess’s 234‑page demonstration endorsed by Cambridge University Press is a paradox that the Britis...

  4. The Political Economy of Sunni-Shi’ah Conflict in Sampang Madura

    Directory of Open Access Journals (Sweden)

    Masdar Hilmy

    2015-06-01

    Full Text Available Many overlooked the fact that politico-economic factors played an important role behind the 2011 and 2012 Sunni-Shi’ah conflict in Sampang Madura. Some, however, argue that the Sunni-Shi’ah conflict was merely driven by theological factors. The major roots of the conflict thus were therefore the internal dimensions of religious beliefs as contained in its doctrines. As a result, the conflict can only be explained in terms of religious and theological framework. This assumption is commonly shared by the majority of Madurese Muslims by arguing that the island of Madura cannot host the believers of non-Sunni. In the aftermath of the conflict, the community of Shi’ah has been forced to seek refuge outside of the land of Madura. By doing so, many observers and the Madurese Muslims tends to have treated political and economic factors as peripheral that exacerbated the escalation of conflict. This article, however, argues vice-versa that it is not theology, but politics and economy, which mainly steered the conflict. Theology played a role in exacerbating the escalation of conflict. During the conflict, religious and theological arguments were deployed as a mobilizing force in order to justify the conflict. Furthermore, the existence of Shi’ah community in Sampang is regarded by the mainstream Sunni community as a threat to their long domination over the socio-political structure in that region. The paper, thus, perceives the conflict as the way the local elites maintain the established mode of production. This paper is qualitative research that employs political-economy as its main approach in analyzing the data. [Para pengamat banyak tidak melihat aktor politik dan ekonomi di balik konflik Sunni dan Syiah 2011 dan 2012 di Sampang Madura. Para peneliti bahkan beranggapan bahwa konflik Sunni-Syiah itu dilatari oleh faktor teologis. Ini artinya bahwa tiap kelompok memegang sistem kepercayaan yang berbeda. Akar utama dari konflik itu pada

  5. Inter-religious feelings of Sunni and Alevi Muslim minorities : The role of religious commitment and host national identification

    OpenAIRE

    Martinovic, Borja; Verkuyten, Maykel

    2016-01-01

    This paper examines inter-religious attitudes from the perspective of Muslim minorities living in Western Europe. We examine both Sunni and Alevi Muslims of Turkish origin living in Germany and the Netherlands, and focus on their global feelings towards multiple religious out-groups (Christians, Jews, Muslim out-group, and non-believers). We hypothesize that Sunnis would dislike religious out-groups more than Alevis, and that these group differences in religious out-group feelings can be expl...

  6. Sexualidad violenta en el cine de Kim Ki-duk

    Directory of Open Access Journals (Sweden)

    Daniel Muñoz Ruiz

    2011-07-01

    Full Text Available En sus más de 110 años de vida el cine ha representado la sexualidad humana en todas sus modalidades y desde los más variados puntos de vista. El cine de Kim Ki-duk ha sorprendido y escandalizado al público por su crudeza y, a veces, excesiva violencia. El director surcoreano ha explorado a lo largo de su filmografía el tema del sexo siempre desde puntos de vista dramáticos y hasta truculentos. En sus películas la mayoría de las relaciones sexuales carecen de amor y afecto. Nunca son placenteras. La violación, la prostitución, la violencia de género y las frustraciones sexuales son temas recurrentes en su cine.

  7. Global Policing and the Case of Kim Dotcom

    Directory of Open Access Journals (Sweden)

    Darren Palmer

    2013-11-01

    Full Text Available In early 2012, 76 heavily armed police conducted a raid on a house in Auckland, New Zealand. The targets were Kim Dotcom, a German national with a NZ residency visa, and several colleagues affiliated with Megaupload, an online subscription-based peer-to-peer (P2P file sharing facility. The alleged offences involved facilitating unlawful file sharing and United States federal criminal copyright violations. Following the raid, several court cases provide valuable insights into emerging ‘global policing’ practices (Bowling and Sheptycki 2012 based on communications between sovereign enforcement agencies.  This article uses these cases to explore the growth of ‘extraterritorial’ police powers that operate ‘across borders’ (Nadelmann 1993 as part of several broader transformations of global policing in the digital age.

  8. Prediction of Potential Distribution of Quadrastichus erythrinae Kim in China

    Institute of Scientific and Technical Information of China (English)

    Zhang; Junzhong; Liu; Jianhong; Yang; Liying; Dan; Wenli

    2014-01-01

    Based on Maxent niche model and combined with ArcGIS,the suitable area range for Quadrastichus erythrinae Kim in China was predicted in the paper.The results showed that high suitable area for Q. erythrinae in China included most northeast coastal areas of Hainan Island,partial southern coastal area of Guangdong Province,partial northwestern coastal area and partial southeast coastal area of Taiwan Island; moderate suitable area included partial area of Hainan,some contiguous areas of Guangxi and Guangdong,most areas of Guangdong,partial area of Fujian and Taiwan; low suitable area included partial area from northwestern coast to inland of Hainan Island,west coastal area of Taiwan Island,most area in Guangxi,partial areas in Guangdong,Fujian and Yunnan.

  9. Microsatellite diversity delineates genetic relationships of Shia and Sunni Muslim populations of Uttar Pradesh, India.

    Science.gov (United States)

    Eaaswarkhanth, Muthukrishnan; Dubey, Bhawna; Ramakodi Meganathan, Poorlin; Noor, Sabahat; Haque, Ikramul

    2009-08-01

    In this study we characterize the genetic diversity and relationships between the Shia and Sunni Muslim populations of North India and geographically targeted neighboring and global populations. We examined a number of parameters of population genetic and forensic interest based on the allele frequencies from 15 autosomal STR loci (D8S1179, D21S11, D7S820, CSF1PO, D19S433, VWA, TPOX, D18S51, D3S1358, THO1, D13S317, D16S539, D2S1338, D5S818, and FGA). All the studied loci were consistent with Hardy-Weinberg equilibrium, except loci D18S51 and FGA for both Muslim populations, even after applying the Bonferroni correction. The combined power of exclusion and combined power of discrimination values for all 15 STR loci were 0.9999 and >0.99999, respectively, in both Muslim populations. Gene diversity values ranged from 0.6784 (TPOX) to 0.9027 (FGA) for Shia Muslims and from 0.7152 (CSF1PO) to 0.9120 (D18S51) for Sunni Muslims. The observed heterozygosity (H(o)) ranged from 0.5833 (D18S51) to 0.8595 (VWA) in Shia Muslims and from 0.6818 (CSF1PO) to 0.8333 (D21S11) in Sunni Muslims and was lower than the expected heterozygosity (H(e)) for 11 out of the 15 STRs typed. We analyzed the genetic affinities of the Shia and Sunni Muslim populations with their geographically closest neighboring North Indian, Middle Eastern, East Asian, and European populations using distance-based methods, including neighbor-joining trees and multidimensional scaling. In addition, we estimated the genetic contribution of the putative parental populations included in the analysis to the Shia and Sunni Muslim gene pool using admixture analysis. Although we observed a certain degree of genetic contribution from Iran to both Muslim populations, the results of the phylogenetic analyses based on autosomal STRs suggest genetic relatedness with some of the geographically closest neighboring Hindu religious populations.

  10. Izvori o riječkim povijesnim novinama 1813. - 1918.

    Directory of Open Access Journals (Sweden)

    Lea Lazzarich

    2009-11-01

    Full Text Available Nedostatak cjelovitog pregleda riječkih povijesnih novina u razdoblju od početaka novinskog tiska u Rijeci 1813. do 1918. godine prouzročio je brojne probleme u istraživanju riječke povijesti, i to kako pojedinih događaja tako i općih okolnosti. Takvo je stanje rezultiralo potrebom komparativnog analiziranja raspoloživih izvora o riječkim povijesnim novinama i, slijedom toga, izrade sustavnog pregleda svih objavljenih naslova u navedenom razdoblju. Tijekom stvaranja takvog pregleda izvori (pod tim se pojmom ovdje podrazumijevaju radovi, ponajprije bibliografije, koji se bave riječkim povijesnim novinama su sustavno i komparativno analizirani te su provjereni podaci o svakom naslovu, ali i sami naslovi koji nisu transparentno navedeni u svim izvorima, s ciljem stvaranja popisa novina prema definiciji i obilježjima. Time je osigurana platforma za daljnji rad i riješen barem dio nedoumica u istraživanju riječkih povijesnih novina. Doprinos istraživanja su novi, dopunjeni i često izmijenjeni podaci o naslovu, impresumu ili periodičnosti pojedinih novina (uz napomenu da se periodičnost nerijetko mijenjala tijekom godina, koji su od ključne važnosti kako u knjižničarskom tako i u povijesnoistraživačkom smislu. Ne prejudicira se da je istraživanje konačno i zatvoreno, već se naglašava nužnost daljnjeg propitivanja podataka o pojedinim povijesnim novinama, uzimajući pritom u obzir činjenicu da je posljednje sustavno istraživanje provođeno prije pedesetak godina.

  11. Tasawuf Sunni Ala Sirhindi : “Kawin Paksa” Monisme dan Teologi Asy’Ariyah

    Directory of Open Access Journals (Sweden)

    Muhsin Labib

    2012-06-01

    Full Text Available Abstract : The term monism or wahdah al-wujūd has a long story in Islamic Mysticism or Sufism. It is such that is considered to be the soul of Sufism, an sich. It means that without wahdah al-wujūd, there would be no further discussion on Islamic Mysticism. Besides, the theory of wahdah al-wujūd is rooted in Shi’ite Islam, yet never found in the theology of Ash’arian or any other Sunni tradition. It is very important to have an awareness of what the author has termed ‘failed cloning’ between monism in Shi’ite and dualism in Sunni traditions established by Sirhindi. This is an attempt to uncover the weakness and/or weaknesses of Sirhindi’s methodology, that criticized wahdah al-wujūd and his subsequent misunderstanding of it. Moreover, Sirhindi seemed somewhat confused over the disciplines of mysticism, philosophy, theology and jurisprudence in his arguments and accordingly his mystical construction. To criticize wahdah al-wujūd without having a basic understanding of Ibn ‘Arabi’s works is a fault. Moreover, the construction of mystical dimension of wahdah al-wujūd of Ibn ‘Arabi which had staunchly strengthened and defended by Shadruddin Shirazi (Mulla Sadra is very difficult to break through by anyone who does not have basic knowledge of either. Thus, Sirhindi should have learned from him (Mulla Sadra before he criticized Ibn ‘Arabi and his concept wahdah al-wujūd.Keywords :  Tasawuf of Sunni, Sirhindi, Monism, Theology of Asy’AriyahAbstrak : Istilah monisme atau wahdah al-wujūd memiliki kisah yang panjang dalam Mistisisme Islam atau Sufisme. Ia dianggap menjadi jiwa sufisme, an sich, yang berarti bahwa tanpa wahdah al-wujūd, tak akan ada diskusi lebih lanjut mengenai Mistisisme Islam. Selain itu, teori yang berakar dalam tradisi syiah islam, belum pernah ditemukan dalam teologi Asy’ariyah atau dalam tradisi sunni lainnya. Penting untuk memiliki kesadaran terhadap apa yang penulis sebut sebagai

  12. Determinants of Hypovitaminosis D in Pregnant Women and Their Newborns in a Sunny Region

    Directory of Open Access Journals (Sweden)

    Roya Kelishadi

    2013-01-01

    Full Text Available Introduction. This study aims to assess the factors associated with 25-hydroxy vitamin D (25(OHD levels in pregnant women and their newborns in a sunny region. Materials and Methods. This cross-sectional study was conducted in 2012 in Isfahan, Iran. It comprised 100 nulliparous singleton pregnant women, selected by random cluster sampling. Laboratory tests were assessed before delivery in mothers and after delivery in their infants’ umbilical cord blood. The P for trend of variables was assessed across the air quality index (AQI quartiles. The associations of AQI and 25(OHD were assessed by multiple linear regression after adjustment for age, body mass index, and dietary intake. Results. Sera of 98 mothers and an equal number of newborns were analyzed. The median (interquartile range, IQR of serum 25(OHD of mothers and neonates was 15.1(12.6, 18.2 ng/mL in mothers and 15.7(12.0, 18.1 ng/mL in neonates, respectively. AQI had an inverse association with serum 25(OHD (Beta = −0.58, P=0.04. The corresponding figure was also inverse and significant for newborns (Beta (SE= −0.51(0.04, P=0.01. Conclusion. The independent inverse association of 25(OHD with air quality can explain the high prevalence of hypovitaminosis D in pregnant women living in this sunny region.

  13. Vitamin D deficiency/insufficiency from childhood to adulthood: Insights from a sunny country

    Science.gov (United States)

    Haimi, Motti; Kremer, Richard

    2017-01-01

    Vitamin D is known to be a key regulator of bone metabolism and is associated with muscle strength. Vitamin D deficiency is widely prevalent worldwide. In adults, vitamin D deficiency has been implicated in numerous health conditions including osteoporosis, cancer, diabetes, and autoimmune diseases. Considerable changes have occurred in lifestyles and childhood activities in the past years. Studies have shown that the children population is at high risks of vitamin D deficiency. The objective of this study was to learn about the extent of vitamin D deficiency in children worldwide and especially in sunny country like Israel. In this article we reviewed the extent and severity of vitamin D deficiency worldwide and especially in Israel, through a very comprehensive review of previous reports and research studies done during the last years. We found reports on vitamin D deficiency in children, which was associated with metabolic syndromes and obesity. It was more prevalent in children who spend less time on outdoor activities, in obese children, and in cases when there was imbalance between nutritional intakes and requirements. Vitamin D deficiency is common even in children living in sunny places like Israel. Health professionals should be aware of the fact that although vitamin D deficiency is prevalent in the elderly population, it is also common in children, and can be associated with different illnesses. We encourage supplementation of vitamin D to special populations (pregnant and lactating women, infants, and high risk groups). We also encourage implementation of international food fortification programs.

  14. Moral institutionalization of Sunny Sports%阳光体育运动的道德制度化

    Institute of Scientific and Technical Information of China (English)

    高晶; 徐勤儿; 佟双艳

    2012-01-01

      The authors clarified concepts such as change of the moral system of Sunny Sports, probed into the ori-enting value, adjusting value and operable value possessed by the moral system of Sunny Sports. On such a basis, the authors analyzed the feasibility and practicability of the moral institutionalization of Sunny Sports from the per-spectives of traditional customs in China, relevant moral systems for school physical education abroad, and realistic needs for developing Sunny Sports, pointed out that the moral institutionalization of Sunny Sports is an important measure for realizing students’ self discipline in sports morals, needed by assuring the effectiveness of college Sunny Sports, and lastly put forward basic ways to the moral institutionalization of Sunny Sports, namely, to estab-lish a good sports moral conception in schools, to form a good sports moral atmosphere;to specify basic principles for the moral institutionalization of Sunny Sports; to perfect school education supervision system, to establish a principal responsibility system.%  对阳光体育运动道德制度变化等概念进行梳理,探讨了阳光体育运动道德制度具有的导向作用、调节作用和可操作性。在此基础上,从我国传统习俗、国外相关的学校体育道德制度和开展阳光体育运动现实需要的角度分析阳光体育运动道德制度化的可行性和实用性,指出阳光体育道德制度化是实现学生主体体育道德自律的重要举措,是保障高校阳光体育运动实效性的需要。最后提出阳光体育运动体育道德制度化的基本路径,即在学校中树立良好的体育道德观念,形成良好的体育道德风气;明确阳光体育运动道德制度化的基本原则;完善学校教育督导制度,建立校长问责机制。

  15. Urbanism PhD Research 2008 - 2010

    NARCIS (Netherlands)

    Van der Hoeven, F.D.; Brand, N.; Van der Burg, L.; Çalışkan, O.; Tan, E.R.; Wang, C.-Y.; Zhou, J.

    2009-01-01

    To ensure the quality of the Ph.D. research the Department introduced a special procedure for periodic evaluation: after a period of nine months the potential Ph.D. candidates are asked to present their research design, theoretical framework and methodological approach to the members of the Departme

  16. A PHD in histone language

    Science.gov (United States)

    Chandrika, Nulu Naga Prafulla; Sundaravelpandian, Kalaipandian; Schmidt, Wolfgang

    2013-01-01

    Post-translational modifications of core histones are important for various DNA-templated processes such as transcription and repair. We recently reported that the ALFIN LIKE 6 (AL6) gene, identified in a forward genetic screen, is critical for phosphate deficiency-induced root hair formation and several other processes associated with the regulation of cellular phosphate homeostasis. AL6 contains a Plant Homeo Domain (PHD) finger that can bind to trimethylated lysine 4 of histone H3 (H3K4me3). Homozygous mutants defective in AL6 expression form very short root hairs under phosphate-deficient conditions, presumably caused by altered expression of putative primary and secondary down-stream targets of AL6. In this Addendum, we speculate about possible roles of AL6, H3K4 trimethylation and other chromatin modifications in the adaptation of plants to low phosphate availability. PMID:23531693

  17. SunnyTALEN: a second-generation TALEN system for human genome editing.

    Science.gov (United States)

    Sun, Ning; Bao, Zehua; Xiong, Xiong; Zhao, Huimin

    2014-04-01

    Transcription activator-like effector nucleases (TALENs) have rapidly emerged as a powerful genome editing tool. The site-specific DNA double-strand breaks generated by TALENs in the human chromosome can induce homologous recombination or non-homologous end joining, resulting in desired genetic modifications. In this study, we report the development of a TALEN variant, SunnyTALEN, with >2.5-fold improved genome editing efficacy in human cells. The corresponding scaffold increases the rate of genetic modification at all the 13 tested loci of human genome and is compatible with heterodimer TALEN architectures. This enhanced and high-efficiency TALEN variant represents a novel second-generation TALEN system and has great potential for biological and therapeutic applications.

  18. Tracing the historical and ideological roots of ISIS: Shi’ite or Sunni?

    Directory of Open Access Journals (Sweden)

    Makrum Makrum

    2016-12-01

    Full Text Available This article describes a comprehensive study of ISIS (the Islamic States of Iraq and Syiria by examining both their historical and ideological roots, Shi’ite or Sunni – including their patterns and terror motives and also by mapping their doctrinal understanding that they adopt. The data stem from various studies, books and news that are widely spread in mass media by literature study (library research. This study was inspired by the emergence of ISIS which in recent years has shocked the world for their savagery and ferocity in committing the murder. Moreover, their leader (Abu Bakr al-Baghdadi has declared himself as the caliph and called on Muslims worldwide to join them. That issue has been a controversy across the Muslim world; many Muslim groups accepted and joined the ISIS, while others rejected its presence. Based on these library research results, it can be inferred that, historically ISIS has existed since 2004 and the origin of ISIS cannot be separated from the existence of Tawhid wa alJihad. In terms of doctrine, the concept of shared leadership of ISIS tends to lead to Sunnis, although al-Baghdadi himself does not meet the criteria to be appointed as caliph. Personally, al-Baghdadi does not posses the leadership capacity required as a caliph, based on one of the caliph’s criteria, that is ‘adalah (justice that he does not have. Artikel ini, dengan menggunakan pendekatan kualitatif, mengkaji akar sejarah dan ideologi ISIS, Syi’ah atau Sunni –termasuk di dalamnya pola dan motif teror–, kemudian memetakan paham doktrinal yang mereka anut agar diperoleh kajian yang komprehensif tentang ISIS. Data diperoleh dari studi kepustakaan (library research yang berasal dari berbagai hasil penelitian, buku, dan berita-berita di media massa. Penulisannya terinspirasi oleh kemunculan ISIS yang pada beberapa tahun terakhir telah menghebohkan masyarakat dunia, karena kebiadaban dan keganasannya dalam melakukan pembunuhan. Selain dari itu

  19. A tiny membrane defending 'us' against 'them': Arabic Internet debate about hymenorraphy in Sunni Islamic law.

    Science.gov (United States)

    Eich, Thomas

    2010-10-01

    In the Sunni Arab world, hymen repair has become a subject of considerable controversy due to a public statement of Egypt's Mufti Guma a in 2007. This paper analyses Guma a's position and the ensuing public debate about it as a means to study the larger conceptions of virginity and the hymen in Middle Eastern societies. In line with critical feminist studies it is shown that supporters as well as critics of the operation rely heavily on patriarchal arguments, views and rhetoric. Both share the societal vision that sexuality can only be lived out licitly in the framework of marriage and both agree that this ideal is in crisis. Where the two sides disagree is over the way in which this ideal should be protected, which derives from their conceptualisation of creation in general and female nature in particular. As a result, debate about hymen repair is not only not transforming social structures but is perpetuating them.

  20. [Is there vitamin D deficiency in children in a sunny Mediterranean city?].

    Science.gov (United States)

    Togo, A; Espadas Maciá, D; Blanes Segura, S; Sivó Díaz, N; Villalba Martínez, C

    2016-03-01

    Despite the increasing interest in vitamin D functions, new cases of deficiency have been reported in sunny regions where optimal levels are expected. The aim of this study was to analyze 25-hydroxivitamin D levels in children younger than 2 years admitted for acute mild diseases in a tertiary hospital in Valencia and its relationship with factors that can be associated with its deficiency. This one year prospective and observational study was conducted on 169 children admitted for acute mild diseases. 25-hydroxivitamin D levels were analyzed. A standardized physical examination and structured interviews to the parents were performed. Children were classified into two groups, according to 25-hydroxivitamin D levels (cut-off 30 ng/mL). A total of 169 children were included, with a median age of 9 months, being more prevalent Caucasians (75.7%) and youger than one year old (79.3%). Almost one quarter (24.3%) of the children had 25-hydroxivitamin D levels 30 ng/mL were associated with vitamin D prophylaxis during the first year, in children of a Caucasian mother, and those who did not wear a hijab. No statistical differences were found in diet characteristics (P=.65). Prophylaxis was given to 47% of the breastfed children younger than one year. In Valencia, Spain, 25-hydroxivitamin D levels lower than 30 ng/mL were found in a quarter of the children younger than two years. Our results emphasize the importance of vitamin D prophylaxis during the first year of life, even in sunny Mediterranean regions. Copyright © 2015 Asociación Española de Pediatría. Published by Elsevier España, S.L.U. All rights reserved.

  1. Inter-religious feelings of Sunni and Alevi Muslim minorities : The role of religious commitment and host national identification

    NARCIS (Netherlands)

    Martinovic, Borja; Verkuyten, Maykel

    2016-01-01

    This paper examines inter-religious attitudes from the perspective of Muslim minorities living in Western Europe. We examine both Sunni and Alevi Muslims of Turkish origin living in Germany and the Netherlands, and focus on their global feelings towards multiple religious out-groups (Christians, Jew

  2. Book Review: Schmidt, Garbi (2004) Islam in Urban America: Sunni Muslims in Chicago, Philadelphia: Temple University Press. ISBN-1592132235

    OpenAIRE

    Ben Moussa, Mohamed

    2007-01-01

    Garbi Schmidt’s Islam in Urban America: Sunni Muslims in Chicago is an invaluable contribution to ethnographic research about Islam and Muslims in the West. It provides an insightful perspective on Muslims’ life in the United States and refutes some of the most common stereotypes about Muslims.

  3. On some results of Bump-Choie and Choie-Kim

    CERN Document Server

    Hundley, Joseph

    2011-01-01

    This paper is motivated by a 2001 paper of Choie and Kim and a 2006 paper of Bump and Choie. The paper of Choie and Kim extends an earlier result of Bol for elliptic modular forms to the setting of Siegel and Jacobi forms. The paper of Bump and Choie provides a representation theoretic interpretation of the phenomenon, and shows how a natural generalization of Choie and Kim's result on Siegel modular forms follows from a natural conjecture regarding (g,K)-modules. In this paper, it is shown that the conjecture of Bump and Choie follows from work of Boe. A second proof which is along the lines of the proof given by Bump and Choie in the genus 2 case is also included, as is a similar treatment of the result of Choie and Kim on Jacobi forms.

  4. ATLAS PhD Grant Scheme

    CERN Multimedia

    2016-01-01

    In this #CERNandSociety video, the 3 PhD students, awarded the ATLAS PhD Grant in 2015, talk about their research work within the ATLAS Collaboration and how this experience has shaped their future. Find out more about the ATLAS PhD Grant Scheme: cern.ch/ATLASPhDGrant This programme is just one of the many #CERNandSociety projects at CERN. Find out more and how you can be involved: http://cern.ch/go/pBt7

  5. Brenda K. Edwards, PhD

    Science.gov (United States)

    Brenda K. Edwards, PhD, has been with the Surveillance Research Program (SRP) and its predecessor organizations at the National Cancer Institute (NCI) since 1989, serving as SRP’s Associate Director from 1990-2011.

  6. Biomedical PhD education - an international perspective

    DEFF Research Database (Denmark)

    Mulvany, Michael J.

    2013-01-01

    The PhD, otherwise known as the doctor of philosophy or Dr. Phil., is an internationally recognized degree, indicating that the PhD graduate has received training in research under supervision. Traditionally, the PhD was the route to an academic career, with most successful PhD graduates receivin...

  7. What PhD students really want

    CERN Document Server

    Mao, Minnie

    2010-01-01

    The road to becoming an astronomer is exciting, but often fraught with danger and conflicting messages. A PhD student is inundated with catch-phrases such as "publish or perish" and "it's not about the quantity, but the quality of work". How do we know which advice to follow? How can we publish copious amounts of quality work in only three years so as to maximize our success in the future? How do we even know what "good quality" really is? With only a short time to prepare ourselves for the big wide world of Astronomy, what is the best way for a PhD student to maximize their research and ultimately maximize their success as a real astronomer? The PhD students of today are the astronomers of tomorrow, but their journey depends on a positive work environment in which they can thrive and improve. Here I present the results of a survey of current PhD students on how they believe they can maximize their success in science. I find that PhD students in Australia expect to write more papers during their PhD than is e...

  8. Hypovitaminosis D in a sunny country: time trends, predictors, and implications for practice guidelines.

    Science.gov (United States)

    Hoteit, Maha; Al-Shaar, Laila; Yazbeck, Cynthia; Bou Sleiman, Maria; Ghalayini, Tala; Fuleihan, Ghada El-Hajj

    2014-07-01

    The aim of the current study is to investigate the prevalence of hypovitaminosis D in Lebanese subjects, its robust predictors, evaluate the relationship between 25 hydroxy vitamin D [25(OH)D] and parathyroid hormone levels, and derive desirable vitamin D levels, based on a large hospital laboratory database spanning all age groups. Data from a large representative digitized database of 9147 subjects, mostly outpatients, evaluated between 2000-2004 and 2007-2008, in whom information on age, gender, service, and time of the year, was analyzed. The PTH-25(OH)D relationship was studied in a subset of 657 adult subjects, in whom such data were available. At a 25(OH)D cut-off ofhypovitaminosis D ranged between 58% and 62% in pediatric subjects, 44% and 60% in adults, and 41% and 62% in elderly, in the 2 study periods. At a cut-off Hypovitaminosis D is prevalent in our sunny country, even using a conservative population-derived cut-off of 20 ng/ml, and thus the need for a public health strategy for supplementation.

  9. The Militarization of Mass Incapacitation and Torture during the Sunni Insurgency and American Occupation of Iraq

    Directory of Open Access Journals (Sweden)

    John L. Hagan

    2016-11-01

    Full Text Available While scholars and journalists have focused important attention on the recent militarization of intensive policing and imprisonment policies in the United States, there is little reciprocal recognition of how militarized versions of these policies were also exported for use in the occupation of Iraq. Intensive policing and imprisonment enabled the American-led and Shia-dominated Iraq Ministries of Defense and Interior along with U.S. forces to play significant roles in the ethnic cleansing and displacement of Arab Sunnis from Baghdad neighborhoods, and in their disproportionate detention in military- and militia-operated facilities, of which the Abu Ghraib prison is only the best known. The failure of American authorities alone and working with Iraq’s government to intervene in stopping the use of police and prisons as places of torture is a violation of U.N.-invoked and U.S.-ratified treaties, and thereby subject to prosecution. Such prosecutions have imported into international law the concept of “joint criminal enterprise” anticipated by the criminologist Donald Cressey and incorporated in the American Racketeer Influenced and Corrupt Organizations (RICO statutes used to convict organized criminals. We elaborate how the concept of joint criminal enterprise can be used to understand and possibly prosecute a chain of command responsibility for the use of policing and prisons as sites of torture in Iraq. We analyze the previously neglected international consequences of U.S. policing, prison, and mass incapacitation strategies with links to American criminology.

  10. Manifestation of malnutrition among Sunni Muslim Girls of Delhi (6-12 years

    Directory of Open Access Journals (Sweden)

    Astha Bansal

    2013-04-01

    Full Text Available Background: Obesity and undernutrition are the opposite extremes on the scale of adiposity, both of which are the manifestation of malnutrition .Childhood obesity are a global epidemic involving both developed and developing countries. It is a state of over-nutrition with long term complications such as dyslipidemia, hypertension, and coronary artery disease and type-2 diabetes. Underweight is the result of under nutrition and conceptualized in term of thinness which is also an important problem among children of developing countries like India, leading to reduction in growth and development of every body organ especially the Central Nervous System. Long term under-nutrition causes failure in linear growth (height of the child. Objective: To assess the nutritional status among Sunni Muslim girls based on recently developed body mass index (BMI cutoff points for children and adolescents. Methods The study subjects were selected form educational institutes of Delhi, India. A total of 370 girls aged 6-12 years were measured and included in the present study. Height and weight were measured and BMI was computed using standard formula. New age and sex specific international cutoff points were utilized to assess nutritional status. Result: In general the mean BMI increased with increasing age. The overall prevalence of thinness, normal weight and overweight were 38.37%, 50% and 11.62% respectively. Present study finds the nutritional stress among girls as evident from the thinness/underweight prevalent among them.

  11. Manifestation of malnutrition among Sunni Muslim Girls of Delhi (6-12 years

    Directory of Open Access Journals (Sweden)

    Astha Bansal

    2013-04-01

    Full Text Available Background: Obesity and undernutrition are the opposite extremes on the scale of adiposity, both of which are the manifestation of malnutrition. Childhood obesity is a global epidemic involving both developed and developing countries. It is a state of over-nutrition with long term complications such as dyslipidemia, hypertension, and coronary artery disease and type-2 diabetes. Underweight is the result of under nutrition and conceptualized in term of thinness which is also an important problem among children of developing countries like India, leading to reduction in growth and development of every body organ especially the Central Nervous System. Long term under-nutrition causes failure in linear growth (height of the child. Objective: To assess the nutritional status among Sunni Muslim girls based on recently developed body mass index (BMI cut-off points for children and adolescents. Methods: The study subjects were selected from educational institutes of Delhi, India. A total of 370 girls aged 6-12 years were measured and included in the present study. Height and weight were measured and BMI was computed using standard formula. New age and sex specific international cut-off points were utilized to assess nutritional status. Result: In general, the mean BMI increased with increasing age. The overall prevalence of thinness, normal weight and overweight were 38.37%, 50% and 11.62%, respectively. Present study finds the nutritional stress among girls as evident from the thinness/underweight prevalent among them.

  12. Bony manifestation of rickets in a sunny city - a case report from Yazd, Iran

    Directory of Open Access Journals (Sweden)

    Mohammadhosain Afrand

    2014-02-01

    Full Text Available Rickets is disease that occurs in growing bones in which defective mineralization occurs in both the bone and the cartilage of the epiphyseal growth plate, resulting in the retardation of growth and skeletal deformities. Rickets is more common in areas with less sunlight. However, this case report presents a case of the bony manifestation of rickets with the intake of vitamin D supplements in Yazd, a city in central Iran that has sunshine almost every day. A patient was referred to an out-patient general pediatric clinic for deformities of the legs and growth disturbance, with his height far below the normal range. The changes that were most evident in his X-rays were the bowing of the long bones of the legs and forearms and the cupping of the wrist metaphyseal region. In summary, we present a patient with bony manifestation of rickets despite living in a sunny area and taking vitamin D supplements. Thus, it is important to remember that rickets is still a common disease among children in Iran. More studies of this issue should be conducted, including the identification of abnormal cases and rescheduling vitamin D supplementation programs

  13. Bony manifestation of rickets in a sunny city - a case report from Yazd, Iran

    Directory of Open Access Journals (Sweden)

    Mohammadhosain Afrand

    2014-01-01

    Full Text Available Rickets is disease that occurs in growing bones in which defective mineralization occurs in both the bone and the cartilage of the epiphyseal growth plate, resulting in the retardation of growth and skeletal deformities. Rickets is more common in areas with less sunlight. However, this case report presents a case of the bony manifestation of rickets with the intake of vitamin D supplements in Yazd, a city in central Iran that has sunshine almost every day. A patient was referred to an out-patient general pediatric clinic for deformities of the legs and growth disturbance, with his height far below the normal range. The changes that were most evident in his X-rays were the bowing of the long bones of the legs and forearms and the cupping of the wrist metaphyseal region. In summary, we present a patient with bony manifestation of rickets despite living in a sunny area and taking vitamin D supplements. Thus, it is important to remember that rickets is still a common disease among children in Iran. More studies of this issue should be conducted, including the identification of abnormal cases and rescheduling vitamin D supplementation programs.

  14. Making Muslim babies: IVF and gamete donation in Sunni versus Shi'a Islam.

    Science.gov (United States)

    Inhorn, Marcia C

    2006-12-01

    Medical anthropological research on science, biotechnology, and religion has focused on the "local moral worlds" of men and women as they make difficult decisions regarding their health and the beginnings and endings of human life. This paper focuses on the local moral worlds of infertile Muslims as they attempt to make, in the religiously correct fashion, Muslim babies at in vitro fertilization (IVF) clinics in Egypt and Lebanon. As early as 1980, authoritative fatwas issued from Egypt's famed Al-Azhar University suggested that IVF and similar technologies are permissible as long as they do not involve any form of third-party donation (of sperm, eggs, embryos, or uteruses). Since the late 1990s, however, divergences in opinion over third-party gamete donation have occurred between Sunni and Shi'ite Muslims, with Iran's leading ayatollah permitting gamete donation under certain conditions. This Iranian fatwa has had profound implications for the country of Lebanon, where a Shi'ite majority also seeks IVF services. Based on three periods of ethnographic research in Egyptian and Lebanese IVF clinics, this paper explores official and unofficial religious discourses surrounding the practice of IVF and third-party donation in the Muslim world, as well as the gender implications of gamete donation for Muslim marriages.

  15. Making muslim babies: Ivf and gamete donation in sunni versus shi’a islam

    Science.gov (United States)

    2006-01-01

    Medical anthropological research on science, biotechnology, and religion has focused on the “local moral worlds” of men and women as they make difficult decisions regarding their health and the beginnings and endings of human life. This paper focuses on the local moral worlds of infertile Muslims as they attempt to make, in the religiously correct fashion, Muslim babies at in vitro fertilization (IVF) clinics in Egypt and Lebanon. As early as 1980, authoritative fatwas issued from Egypt’s famed Al-Azhar University suggested that IVF and similar technologies are permissible as long as they do not involve any form of third-party donation (of sperm, eggs, embryos, or uteruses). Since the late 1990s, however, divergences in opinion over third-party gamete donation have occurred between Sunni and Shi’ite Muslims, with Iran’s leading ayatollah permitting gamete donation under certain conditions. This Iranian fatwa has had profound implications for the country of Lebanon, where a Shi’ite majority also seeks IVF services. Based on three periods of ethnographic research in Egyptian and Lebanese IVF clinics, this paper explores official and unofficial religious discourses surrounding the practice of IVF and third-party donation in the Muslim world, as well as the gender implications of gamete donation for Muslim marriages. PMID:17051430

  16. Kim model for flux-pinning-induced stress in a long cylindrical superconductor

    Science.gov (United States)

    Zeng, Jun; Wang, Xiaogui; Wu, Huaping; Xue, Feng; Zhu, Jun

    2016-07-01

    In this work, the flux-pinning-induced stress distribution in a circular cylinder of high-temperature superconductors is studied by adopting the Kim critical state model to describe the relationship between the magnetic flux density and induced current. Based on the plane strain approach, the analytic expressions of the radial and hoop stress in the cylinder are derived for the zero-field cooling and field cooling magnetization processes. It is shown that the stress distributions depend on the activation processes and the values of the dimensionless parameter p in the Kim model, and the overall maximums of the stresses appear at or near the center of the cylinder where cracking may be most likely initiated. In addition, the Kim model has wider applicability than the Bean model, and the influence of p on the stress depends on the activation process. Generally speaking, these results may be useful for understanding the magnetoelastic problem in practical application of bulk superconductors.

  17. [The medical treatment of Kim Phúc at the BG Unfallklinik Ludwigshafen].

    Science.gov (United States)

    Kiefer, J; Daigeler, A; Lehnhardt, M

    2012-08-01

    The Vietnam War was a military conflict in Vietnam during the Cold War that followed the First Indochina War. This war was fought between North Vietnam, supported by its communist allies, and the government of South Vietnam, supported by the USA and other anti-communist countries. Kim Phúc is the child depicted in the Pulitzer Prize winning photograph taken on June 8, 1972 by AP photographer Nick Út. The iconic photo shows her at about nine years of age running naked on a road amid the chaos after being severely burned by a napalm attack. After 14 months of hospital stay and 17 surgical procedures Kim Phúc was able to return home. Since then, she was used as a propaganda symbol by the communist government of Vietnam. To continue her studies, Kim was granted permission to move to Cuba where she met her future husband. However, the sequelae of her burn wounds affected her everyday life enormously. In 1984, with the support of the international aid organization "terre des hommes" and the German magazine "STERN", Kim Phúc got the opportunity to meet and get treated by Professor Zellner. Professor Peter Rudolph Zellner was the first chief of the Department of Hand, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, and one of the founder members of the German Society of Plastic Surgeons. The reconstructive surgeries provide Kim Phúc an almost normal life. Later on, she was involved in international aid organizations; she was named a UNESCO Goodwill Ambassador and she was awarded several honorary Doctorates of Law. Kim Phúc became a Canadian citizen. Today, she lives with her husband and two children in Ontario, Canada. © Georg Thieme Verlag KG Stuttgart · New York.

  18. Dramaturgi Citra Pemimpin Korea Utara Kim Jong Un dalam Film The Interview Produksi Columbia Pictures

    OpenAIRE

    2016-01-01

    This study titled “Dramaturgy of the image of North Korean leader Kim Jong Un in the film The Interview”. The duration of The Interview film is 112 minutes told a story about the murder plan North Korean leader Kim Jong Un by intelligence services, the United States 'CIA' through two media workers that Dave Skylark and Aaron Rapoport, which is a host and producer of the program infotainment show in United States named Skylark Tonight. This study uses analysis of Erving Goffman Dramaturgy pers...

  19. Lessons learned from 15 years of KIMS and 5 years of ACROSTUDY

    DEFF Research Database (Denmark)

    Luger, Anton; Feldt-Rasmussen, Ulla; Abs, Roger;

    2011-01-01

    BACKGROUND: Pharmacoepidemiological surveys provide a valuable contribution to the continued monitoring of drug-related effects in patients with rare disorders. One of the earliest examples of this type of survey is KIGS (Pfizer International Growth Study Database), which has monitored the safety...... and effectiveness of growth hormone (GH) therapy in GH-deficient children since its inception in 1987. Following closely in the footsteps of KIGS is KIMS (Pfizer International Metabolic Database). As of 2009, KIMS has been collecting data on the long-term safety and clinical outcomes of GH replacement in GH...

  20. Urinary KIM-1 and AQP-1 in patients with clear renal cell carcinoma: Potential noninvasive biomarkers

    Directory of Open Access Journals (Sweden)

    Mijušković Mirjana

    2016-01-01

    Full Text Available Background/Aim. Kidney injury molecule-1 (KIM-1 and aquaporin-1 (AQP-1 are potential early urinary biomarkers of clear renal cell carcinoma (cRCC. The aim of this study was to ascertain relationship between the urine concentrations KIM-1 and AQP-1 with tumor size, grade, pT stage and type of operation (radical or partial nephrectomy in patients with cRCC. Methods. Urinary concentrations of urinary KIM-1 (uKIM-1 and urinary AQP-1 (uAQP-1 were determined by commercially available ELISA kits. The analysis included 40 patients undergoing partial or radical nephrectomy for cRCC and 40 age- and sex-matched healthy adult volunteers. Results. The median preoperative concentrations of KIM-1 in the cRCC group [0.724 ± 1.120 ng/mg urinary creatinine (Ucr] were significantly greater compared with controls (healthy volunteers (0.210 ± 0.082 ng/mgUcr (p = 0.0227. Postoperatively, uKIM-1 concentration decreased significantly to control values (0.177 ± 0.099 ng/mgUcr vs 0.210 ± 0.082 ng/mgUcr, respectively. The size, grade and stage of tumor were correlated positively with preoperative uKIM-1 concentrations. Contrary to these results, concentrations of uAQP-1 in the cRCC group were significantly lower (0.111 ± 0.092 ng/mgUcr compared with the control group (0.202 ± 0.078 ng/mgUcr (p = 0.0014. Postoperatively, the concentrations of uAQP-1 increased progressively up to control values, approximately. We find no significant correlation between preoperative uAQP-1 concentrations and tumor size, grade and stage. Conclusion. uKIM-1 was found to be a reliable diagnostic marker of cRCC, based on its significantly increased values before and decreased values after the nephrectomy. [Projekat Ministarstva nauke Republike Srbije, br. III41018

  1. PREVALENCE OF NEURAL TUBE DEFECTS IN KIMS KARAD, 2012-2013 EFFECTIVENESS AND IMPACT OF PRENATAL DIAGNOSIS

    Directory of Open Access Journals (Sweden)

    Sanjaykumar

    2014-11-01

    Full Text Available : OBJECTIVE: To determine Prevalence of NEURAL TUBE DEFECT in tertiary care center (KIMS Karad during July 2012-July 2013. MATERIAL AND METHODS: Patients referred to KIMS as NTD, Booked Patients diagnosed in KIMS as having neural tube defect based on ultrasound findings. RESULTS: Total prevalence of neural tube defect in KIMS from July 2012-July 2013 was 8.2/1000 births. Prevalence of different types of NTD-Anencephaly was 2.8 and spina bifida was 7.4. CONCLUSION: Aim of this study is to create awareness of NTD in order to prevent NTD by measures like periconceptional folic acid supplementation.

  2. ATLAS PhD Grants 2015

    CERN Multimedia

    Marcelloni De Oliveira, Claudia

    2015-01-01

    ATLAS PHd Grants - We are excited to announce the creation of a dedicated grant scheme (thanks to a donation from Fabiola Gianotti and Peter Jenni following their award from the Fundamental Physics Prize foundation) to encourage young and high-caliber doctoral students in particle physics research (including computing for physics) and permit them to obtain world class exposure, supervision and training within the ATLAS collaboration. This special PhD Grant is aimed at graduate students preparing a doctoral thesis in particle physics (incl. computing for physics) to spend one year at CERN followed by one year support also at the home Institute.

  3. Arhitektuurimuuseum vaatab Aasiasse / Kim Sung Hong ; intervjueerinud Karin Hallas-Murula

    Index Scriptorium Estoniae

    Kim Sung Hong

    2009-01-01

    Näituse kuraatori Kim Sung Hongiga 21. aprillini Eesti Arhitektuurimuuseumis avatud Lõuna-Korea kaasaegse arhitektuuri näitusest "Megacity network" ("Megalinna võrgustik"), Korea arhitektuurist, arhitektidest, muinsuskaitsest ja avalikust ruumist. Näituse kujundas Hwang Doo Jin

  4. Kim 3: an Ultra-faint Star Cluster in the Constellation of Centaurus

    CERN Document Server

    Kim, Dongwon; Mackey, Dougal; Da Costa, Gary S; Milone, Antonino P

    2015-01-01

    We report the discovery of an ultra-faint star cluster in the constellation of Centaurus. This new stellar system, Kim 3, features a half light radius of $r_{h}=2.29^{+1.28}_{-0.52}$ pc and a total luminosity of $M_{V}=+0.7\\pm0.3$. Approximately 26 stars are identified as candidate member stars down to four magnitudes below the main-sequence turn-off, which makes Kim 3 the least luminous star cluster known to date. The compact physical size and extreme low luminosity place it close to faint star clusters in the size-luminosity plane. The stellar population of Kim 3 appears to be relatively young ($9.5^{+3.0}_{-1.7}$ Gyr) and metal-poor ([Fe/H]$=-1.6^{+0.45}_{-0.30}$) at a heliocentric distance of $15.14^{+1.00}_{-0.28}$ kpc. The cluster lacks a well-defined center and a small but prominent group of stars consistent with the Kim 3 isochrone is present approximately 9.7 pc in projection south of the cluster center. Both are signs of the cluster being in the final stage of tidal disruption.

  5. Ever Searching for Better Living——Tan Sri Lee Kim Yew and his CHHB Group

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Visionary Entrepreneur There have been many spectacular feats and achievements by Malaysians in the last two decade,but none as uneXpected and hard-fought as the rise of Tan Sri Lee Kim Yew,Group Managing Director and Founder of CHHB.

  6. A Misleading Review of Response Bias: Comment on McGrath, Mitchell, Kim, and Hough (2010)

    Science.gov (United States)

    Rohling, Martin L.; Larrabee, Glenn J.; Greiffenstein, Manfred F.; Ben-Porath, Yossef S.; Lees-Haley, Paul; Green, Paul; Greve, Kevin W.

    2011-01-01

    In the May 2010 issue of "Psychological Bulletin," R. E. McGrath, M. Mitchell, B. H. Kim, and L. Hough published an article entitled "Evidence for Response Bias as a Source of Error Variance in Applied Assessment" (pp. 450-470). They argued that response bias indicators used in a variety of settings typically have insufficient data to support such…

  7. Lõuna-Korea teatel võib Kim peagi surra / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2009-01-01

    Viidates Lõuna-Korea ja Hiina luureandmetele, väidab Lõuna-Korea meedia, et Põhja-Korea liidril Kim Jong-ilil on kõhunäärmevähk ja talle pole antud elada rohkem kui 5 aastat. Põhja-Korea valitsejadünastia

  8. Dlaczego Korea?czycy z P??nocy akceptuj? w?adz? Kim?w?

    OpenAIRE

    Zdenkowska, Marcelina

    2016-01-01

    Celem artyku?u jest przedstawienie dw?ch popularnych teorii dotycz?cych problemu w?adzy w Korei P??nocnej. Analizie zostan? poddane tezy: konfucjanistyczna i nacjonalistyczna. Podj?te tu rozwa?ania maj? na celu odpowiedzie? na pytanie dlaczego Korea?czycy z P??nocy akceptuj? w?adz? Kim?w? Marcelina Zdenkowska

  9. KIM 3: An Ultra-faint Star Cluster in the Constellation of Centaurus

    Science.gov (United States)

    Kim, Dongwon; Jerjen, Helmut; Mackey, Dougal; Da Costa, Gary S.; Milone, Antonino P.

    2016-04-01

    We report the discovery of an ultra-faint star cluster in the constellation of Centaurus. This new stellar system, Kim 3, features a half-light radius of {r}h={2.29}-0.52+1.28 pc and a total luminosity of MV = +0.7 ± 0.3. Approximately 26 stars are identified as candidate member stars down to four magnitudes below the main-sequence turn-off, which makes Kim 3 the least luminous star cluster known to date. The compact physical size and extreme low luminosity place it close to faint star clusters in the size-luminosity plane. The stellar population of Kim 3 appears to be relatively young ({9.5}-1.7+3.0 Gyr) and metal-poor ([Fe/H]\\quad =\\quad -{1.6}-0.30+0.45) at a heliocentric distance of {15.14}-0.28+1.00 kpc. The cluster lacks a well-defined center, and a small but prominent group of stars consistent with the Kim 3 isochrone is present approximately 9.7 pc in projection south of the cluster center. Both are signs of the cluster being in the final stage of tidal disruption.

  10. Arhitektuurimuuseum vaatab Aasiasse / Kim Sung Hong ; intervjueerinud Karin Hallas-Murula

    Index Scriptorium Estoniae

    Kim Sung Hong

    2009-01-01

    Näituse kuraatori Kim Sung Hongiga 21. aprillini Eesti Arhitektuurimuuseumis avatud Lõuna-Korea kaasaegse arhitektuuri näitusest "Megacity network" ("Megalinna võrgustik"), Korea arhitektuurist, arhitektidest, muinsuskaitsest ja avalikust ruumist. Näituse kujundas Hwang Doo Jin

  11. Lõuna-Korea teatel võib Kim peagi surra / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2009-01-01

    Viidates Lõuna-Korea ja Hiina luureandmetele, väidab Lõuna-Korea meedia, et Põhja-Korea liidril Kim Jong-ilil on kõhunäärmevähk ja talle pole antud elada rohkem kui 5 aastat. Põhja-Korea valitsejadünastia

  12. Migrant Writing in Quebec : Female Mobility in Kim Thúy’s Ru

    NARCIS (Netherlands)

    den Toonder, Jeanette; Averis, Kate; Hollis-Touré, Isabel

    2016-01-01

    This chapter presents the experience of mobility as one of duality, an experience of both rupture and continuity as expressed in the poetic prose of Kim Thúy, resident in Quebec since her departure from her native Vietnam at ten years of age. Describing an experience of fragmented simultaneity that

  13. From isolated GH deficiency to multiple pituitary hormone deficiency: an evolving continuum - a KIMS analysis

    DEFF Research Database (Denmark)

    Klose, M.; Jonsson, B.; Abs, R.;

    2009-01-01

    with organic AO-GHD, who were GH naive prior to entry into the Pfizer International Metabolic Database (KIMS; 283 (7%) IGHD, 3827 MPHD). The effect of GH replacement after 2 years was assessed in those with available follow-up data (133 IGHD, 2207 MPHD), and development of new deficiencies in those...

  14. The first clinical treatment with kilovoltage intrafraction monitoring (KIM): A real-time image guidance method

    Energy Technology Data Exchange (ETDEWEB)

    Keall, Paul J., E-mail: paul.keall@sydney.edu.au; O’Brien, Ricky; Huang, Chen-Yu [Radiation Physics Laboratory, Sydney Medical School, University of Sydney, Camperdown, New South Wales 2006 (Australia); Aun Ng, Jin [Radiation Physics Laboratory, Sydney Medical School, University of Sydney, Camperdown, New South Wales 2006, Australia and School of Physics, University of Sydney, Camperdown, New South Wales 2006 (Australia); Colvill, Emma [Radiation Physics Laboratory, Sydney Medical School, University of Sydney, Camperdown, New South Wales 2006, Australia and Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, New South Wales 2065 (Australia); Rugaard Poulsen, Per; Fledelius, Walther [Department of Oncology, Aarhus University Hospital, 8000 Aarhus C, Denmark and Institute of Clinical Medicine, Aarhus University, 8000 Aarhus C (Denmark); Juneja, Prabhjot; Booth, Jeremy T. [School of Physics, University of Sydney, Camperdown, New South Wales 2006, Australia and Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, New South Wales 2065 (Australia); Simpson, Emma; Bell, Linda; Alfieri, Florencia; Eade, Thomas; Kneebone, Andrew [Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, New South Wales 2065 (Australia)

    2015-01-15

    Purpose: Kilovoltage intrafraction monitoring (KIM) is a real-time image guidance method that uses widely available radiotherapy technology, i.e., a gantry-mounted x-ray imager. The authors report on the geometric and dosimetric results of the first patient treatment using KIM which occurred on September 16, 2014. Methods: KIM uses current and prior 2D x-ray images to estimate the 3D target position during cancer radiotherapy treatment delivery. KIM software was written to process kilovoltage (kV) images streamed from a standard C-arm linear accelerator with a gantry-mounted kV x-ray imaging system. A 120° pretreatment kV imaging arc was acquired to build the patient-specific 2D to 3D motion correlation. The kV imager was activated during the megavoltage (MV) treatment, a dual arc VMAT prostate treatment, to estimate the 3D prostate position in real-time. All necessary ethics, legal, and regulatory requirements were met for this clinical study. The quality assurance processes were completed and peer reviewed. Results: During treatment, a prostate position offset of nearly 3 mm in the posterior direction was observed with KIM. This position offset did not trigger a gating event. After the treatment, the prostate motion was independently measured using kV/MV triangulation, resulting in a mean difference of less than 0.6 mm and standard deviation of less than 0.6 mm in each direction. The accuracy of the marker segmentation was visually assessed during and after treatment and found to be performing well. During treatment, there were no interruptions due to performance of the KIM software. Conclusions: For the first time, KIM has been used for real-time image guidance during cancer radiotherapy. The measured accuracy and precision were both submillimeter for the first treatment fraction. This clinical translational research milestone paves the way for the broad implementation of real-time image guidance to facilitate the detection and correction of geometric and

  15. What My Ph.D. Taught Me

    Science.gov (United States)

    Levenstein, Jessica

    2013-01-01

    The author started in the Ph.D. program in comparative literature at Princeton in 1992, a year after she graduated from college. She fell in love with mythology and the classical traditions and find herself teaching literature. In the remainder of her time at Princeton, she precepted for four or five more classes, got the chance to join the…

  16. Retention of prolyl hydroxylase PHD2 in the cytoplasm prevents PHD2-induced anchorage-independent carcinoma cell growth

    Energy Technology Data Exchange (ETDEWEB)

    Jokilehto, Terhi [Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku (Finland); Turku Graduate School of Biomedical Sciences, Turku (Finland); Hoegel, Heidi [Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku (Finland); Heikkinen, Pekka [Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku (Finland); Turku Graduate School of Biomedical Sciences, Turku (Finland); Rantanen, Krista [Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku (Finland); Elenius, Klaus [Department of Oncology and Radiotherapy, University of Turku and Turku University Hospital, Turku (Finland); Department of Medical Biochemistry and Genetics, University of Turku and Turku University Hospital, Turku (Finland); Sundstroem, Jari [Department of Pathology, University of Turku and Turku University Hospital, Turku (Finland); Jaakkola, Panu M. [Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku (Finland); Department of Oncology and Radiotherapy, University of Turku and Turku University Hospital, Turku (Finland)

    2010-04-15

    Cellular oxygen tension is sensed by a family of prolyl hydroxylases (PHD1-3) that regulate the degradation of hypoxia-inducible factors (HIF-1{alpha} and -2{alpha}). The PHD2 isoform is considered as the main downregulator of HIF in normoxia. Our previous results have shown that nuclear translocation of PHD2 associates with poorly differentiated tumor phenotype implying that nuclear PHD2 expression is advantageous for tumor growth. Here we show that a pool of PHD2 is shuttled between the nucleus and the cytoplasm. In line with this, accumulation of wild type PHD2 in the nucleus was detected in human colon adenocarcinomas and in cultured carcinoma cells. The PHD2 isoforms showing high nuclear expression increased anchorage-independent carcinoma cell growth. However, retention of PHD2 in the cytoplasm inhibited the anchorage-independent cell growth. A region that inhibits the nuclear localization of PHD2 was identified and the deletion of the region promoted anchorage-independent growth of carcinoma cells. Finally, the cytoplasmic PHD2, as compared with the nuclear PHD2, less efficiently downregulated HIF expression. Forced HIF-1{alpha} or -2{alpha} expression decreased and attenuation of HIF expression increased the anchorage-independent cell growth. However, hydroxylase-inactivating mutations in PHD2 had no effect on cell growth. The data imply that nuclear PHD2 localization promotes malignant cancer phenotype.

  17. Urinary Kidney Injury Molecule-1 (KIM-1 in Early Diagnosis of Acute Kidney Injury in Pediatric Critically Ill

    Directory of Open Access Journals (Sweden)

    Irma Lestari Paramastuty

    2016-04-01

    Full Text Available Acute kidney injury (AKI often associated with a high hospital morbi-mortality rate in the intensive care unit patients. Kidney injury molecule-1 (KIM-1, has many characteristics of ideal biomarker for kidney injury. The aim of this study was to compared the temporal pattern of elevation urinary KIM-1 level following critically ill children with SCr as standart biomarker of AKI. Prospective analytic observational study was conducted during October to March 2014 in the Saiful Anwar General Hospital and Physiology Laboratory Brawijaya University. There were 13 critically ill as subjects. SCr and KIM-1 levels from all subjects were measured three times ( at admission, after 1st and 6th hour. Subjects were devided into AKI - non-AKI groups by SCr level and survivor - non survivor group at the and of the observations. Results showed that there were significantly increased levels of KIM-1 in the AKI and non-AKI and survivor-non survivor group at time point. However, we found that delta KIM-1 at time point increased significant in non AKI group and survivor group. KIM-1 at admission can diagnosed AKI in critically ill children. We conclude that urinary KIM-1 is a sensitive non-invasive biomarker to diagnosed acute kidney injury in critically ill children. Increase level of KIM-1 by time shows protective and good outcome in critically ill children.

  18. Innovate Culture of Police Barrack, Cultivate Sunny Attitude%创新警营文化培育阳光心态

    Institute of Scientific and Technical Information of China (English)

    王红霞

    2012-01-01

    Sunny Policeman" is the core and basis of "Sunny Action". How to become a "Sunny Policeman" with sunny attitude is an important issue for our public security field. So based on practical work in police station, Dunhafang police station of Xinghualing branch,Taiyuan Public Security Bureau did research on it actively, innovated thinking and released a series of new measures which aimed to cultivate policemen' s sunny attitude by culture of police barrack.%在“阳光行动”中,“阳光警察”是核心,是基础,而警察如何具备阳光心态成长为“阳光警察”,是当前我省公安队伍所面临的一个重大课题。为此,太原市公安局杏花岭分局敦化坊派出所积极探索,创新思路,在结合公安派出所工作实际的基础上,因地制宜,推出了一系列创新举措,以特色警营文化来培育民警的阳光心态。

  19. PhD Students' Work Conditions and Study Environment in University- and Industry-Based PhD Programmes

    Science.gov (United States)

    Kolmos, A.; Kofoed, L. B.; Du, X. Y.

    2008-01-01

    During the last 10 years, new models of funding and training PhD students have been established in Denmark in order to integrate industry into the entire PhD education. Several programmes have been conducted where it is possible to co-finance PhD scholarships or to become an employee as an industrial PhD in a company. An important question is what…

  20. Experimental study for Yuen-Kim protocol of quantum key distribution with unconditional secure

    OpenAIRE

    Hirota, O.; Kato, K; Sohma, M.

    2002-01-01

    In this report, we simulate practical feature of Yuen-Kim protocol for quantum key distribution with unconditional secure. In order to demonstrate them experimentally by intensity modulation/direct detection(IMDD) optical fiber communication system, we use simplified encoding scheme to guarantee security for key information(1 or 0). That is, pairwise M-ary intensity modulation scheme is employed. Furthermore, we give an experimental implementation of YK protocol based on IMDD.

  1. ATLAS PhD Grant Scholarship Programme

    CERN Multimedia

    Abha Eli Phoboo

    2014-01-01

    On 11 February, the first recipients of the ATLAS PhD Grant were presented with a certificate by the programme’s selection committee. The three scholars - Lailin Xu of China, Josefina Alconada of Argentina and Gagik Vardanyan of Armenia - were delighted at being able to continue their PhD programmes at CERN.   With certificates, from left: Lailin Xu, Josefina Alconada, and Gagik Vardanyan. The selection committee members, from left: IFAE Barcelona’s Martine Bosman, Fabiola Gianotti, Peter Jenni and from CERN HR James Purvis. (Image: ATLAS/Claudia Marcelloni). Former ATLAS spokespersons Peter Jenni and Fabiola Gianotti started the fund with the Fundamental Physics Prize award money they received last year. Both have used the entirety of their prizes for educational and humanitarian programmes. "We wanted to do something for students who are working on ATLAS, in particular those who otherwise could not come here and actually see the detector they are working on,&am...

  2. PhD students share their work

    CERN Multimedia

    Joannah Caborn Wengler

    2012-01-01

    Last week, the second Doctoral Student Assembly gave students in the final stages of their PhD at CERN the chance to meet and present their work.   On 9 May, 24 students who are completing their PhD under the CERN Doctoral Student Programme were joined by their CERN supervisors and some of their university supervisors at an event organised by HR and the Technical Students Committee (TSC). After an address by the Director-General Rolf Heuer and short presentations by Ingrid Haug from HR and TSC Chair Stephan Russenschuck, the students presented their work in a poster session. Held in a packed Council Chamber, the event was a great opportunity for the doctoral students to get to know each other and to share their work in fields as diverse as radiation protection, computing, physics and engineering.

  3. PhD competences of food studies

    Directory of Open Access Journals (Sweden)

    Chelo Gonzalez-Martinez

    2014-10-01

    Full Text Available In European Higher Education, learning outcomes and competences have been used sometimes with different meanings and sometimes with the same meaning. But both terms have been more commonly used to refer to knowledge, understanding and abilities a student must demonstrate at the end of a learning experience.  Their use is a consequence of the paradigm shift of the Bologna Process to a learner centered education environment. The definition of standards of competences (or learning outcomes for the PhD degree is thus a need for the quality assurance of this degree. In this work, subject-specific and generic competences for the PhD in Food Science and Technology and their alignment with the European Qualifications Framework (EQF level descriptors for quality assurance purposes have been identified.

  4. Living in the hands of God. English Sunni e-fatwas on (non-)voluntary euthanasia and assisted suicide.

    Science.gov (United States)

    Van den Branden, Stef; Broeckaert, Bert

    2011-02-01

    Ever since the start of the twentieth century, a growing interest and importance of studying fatwas can be noted, with a focus on Arabic printed fatwas (Wokoeck 2009). The scholarly study of end-of-life ethics in these fatwas is a very recent feature, taking a first start in the 1980s (Anees 1984; Rispler-Chaim 1993). Since the past two decades, we have witnessed the emergence of a multitude of English fatwas that can easily be consulted through the Internet ('e-fatwas'), providing Muslims worldwide with a form of Islamic normative guidance on a huge variety of topics. Although English online fatwas do provide guidance for Muslims and Muslim minorities worldwide on a myriad of topics including end-of-life issues, they have hardly been studied. This study analyses Islamic views on (non-)voluntary euthanasia and assisted suicide as expressed in English Sunni fatwas published on independent--i.e. not created by established organisations--Islamic websites. We use Tyan's definition of a fatwa to distinguish between fatwas and other types of texts offering Islamic guidance through the Internet. The study of e-fatwas is framed in the context of Bunt's typology of Cyber Islamic Environments (Bunt 2009) and in the framework of Roy's view on the virtual umma (Roy 2002). '(Non-)voluntary euthanasia and assisted suicide' are defined using Broeckaert's conceptual framework on treatment decisions at the end of life (Broeckaert 2008). We analysed 32 English Sunni e-fatwas. All of the e-fatwas discussed here firmly speak out against every form of active termination of life. They often bear the same structure, basing themselves solely on Quranic verses and prophetic traditions, leaving aside classical jurisprudential discussions on the subject. In this respect they share the characteristics central in Roy's typology of the fatwa in the virtual umma. On the level of content, they are in line with the international literature on Islamic end-of-life ethics. English Sunni e-fatwas make

  5. Ecological evaluation of proposed dredged material from Wilmington Harbor and Military Ocean Terminal, Sunny Point, North Carolina

    Energy Technology Data Exchange (ETDEWEB)

    Ward, J.A.; Pinza, M.R.; Barrows, M.E.; Word, J.Q. [Battelle/Marine Sciences Lab., Sequim, WA (US)

    1993-07-01

    This report is intended to provide information required to address potential ecological effects of the proposed disposal of Wilmington Harbor and Military Ocean Terminal, Sunny Point (MOTSU), North Carolina, sediments in the ocean. The report is divided into five sections. Section 1.0 is the introduction containing a brief overview of the study and the study objectives. Section 2.0 describes the methods and materials used for sample collection, processing, toxicological and bioaccumulation testing, physical/chemical analysis of sediments and tissues, data analysis, and quality assurance procedures. Section 3.0 presents the results of field collections, sediment chemistry, toxicological testing, and tissue chemistry resulting from bioaccumulation exposures. Section 4.0 presents a discussion of the results and summary conclusions concerning the acceptability of the Wilmington Harbor and MOTSU dredged material for ocean disposal. Section 5.0 lists the literature cited in support of this document. A series of appendixes contain detailed data listings.

  6. Phenotypic characterization of OmpX, an Ail homologue of Yersinia pestis KIM.

    Science.gov (United States)

    Kolodziejek, Anna M; Sinclair, Dylan J; Seo, Keun S; Schnider, Darren R; Deobald, Claudia F; Rohde, Harold N; Viall, Austin K; Minnich, Scott S; Hovde, Carolyn J; Minnich, Scott A; Bohach, Gregory A

    2007-09-01

    The goal of this study was to characterize the Yersinia pestis KIM OmpX protein. Yersinia spp. provide a model for studying several virulence processes including attachment to, and internalization by, host cells. For Yersinia enterocolitica and Yersinia pseudotuberculosis, Ail, YadA and Inv, have been implicated in these processes. In Y. pestis, YadA and Inv are inactivated. Genomic analysis of two Y. pestis strains revealed four loci with sequence homology to Ail. One of these genes, designated y1324 in the Y. pestis KIM database, encodes a protein designated OmpX. The mature protein has a predicted molecular mass of 17.47 kDa, shares approximately 70 % sequence identity with Y. enterocolitica Ail, and has an identical homologue, designated Ail, in the Y. pestis CO92 database. The present study compared the Y. pestis KIM6(+) parental strain with a mutant derivative having an engineered disruption of the OmpX structural gene. The parental strain (and a merodiploid control strain) expressed OmpX at 28 and 37 degrees C, and the protein was detectable throughout all phases of growth. OmpX was required for efficient adherence to, and internalization by, cultured HEp-2 cell monolayers and conferred resistance to the bactericidal effect of human serum. Deletion of ompX resulted in a significantly reduced autoaggregation phenotype and loss of pellicle formation in vitro. These results suggest that Y. pestis OmpX shares functional homology with Y. enterocolitica Ail in adherence, internalization into epithelial cells and serum resistance.

  7. Kim Jong IL and North Korea: The Leader and the System

    Science.gov (United States)

    2006-03-01

    bo rn d = di ed (f) = fe m al e Fi gu re 4 . T he K im F am ily . n o TE : C om pi le d by a ut ho r. 17 • Song Hye Rim: mother of Kim Jong...Madeleine Albright with Bill Woodward, Madam Secretary, New York: Miramax Books, 2003, p. 465. 20. Cited in Oh and Hassig, North Korea, p. 91. 21. Some...12. 28. Albright, with Woodward, Madam Secretary, pp. 462, 467. 29. For a more detailed analysis of North Korean intentions, see Andrew Scobell

  8. Pursuit of the Ph.D.

    Directory of Open Access Journals (Sweden)

    Scott P. Kerlin

    1995-11-01

    Full Text Available he thesis is put forward that changes in public policy which originally promoted broad access to higher education are leading to the diminished likelihood that minorities, those from low-income backgrounds and females in underrepresented disciplines will pursue, or be able to complete, the doctorate. By reviewing a wide range of research literature and statistical reports on the status of doctoral education in the U.S. & Canada, a detailed sociological portrait of those who pursue the Ph.D. is presented. Recommendations are given for further research on doctoral education, particularly in areas of attrition,retention, student indebtedness, social stratification, and post-doctoral career plans.

  9. New Synthesis Route for PHD Polyols

    OpenAIRE

    Peshkov, Vladimir; Evtimova, Rozeta; Herzog, Michael; Behrendt, Gerhard

    2011-01-01

    The synthesis of polyurea dispersion polyols (PHD) was developed using a new route via depolymerization of polyurethane polyureas by a mixture of at least two glycols in the presence of a consumable catalyst, i. e. a secondary aliphatic amine. On this way such polyols were produced with a particle size distribution with a maximum in the 120 to 400 nanometer region with hydroxyl numbers of 180 to 300 mg KOH/g being optically clear and highly reactive. The exact adjustment of the ethylene oxide...

  10. 33 CFR 334.450 - Cape Fear River and tributaries at Sunny Point Army Terminal, Brunswick County, N.C.; restricted...

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Cape Fear River and tributaries... AND RESTRICTED AREA REGULATIONS § 334.450 Cape Fear River and tributaries at Sunny Point Army Terminal, Brunswick County, N.C.; restricted area. (a) The area. That portion of Cape Fear River due west of the main...

  11. Cloudy with a Chance of Sarcasm or Sunny with High Expectations: Using Best Practice Language to Strengthen Positive Behavior Intervention and Support Efforts

    Science.gov (United States)

    Holloman, Hal; Yates, Peggy H.

    2013-01-01

    What's the forecast in your classroom? Are you forecasting cloudy with a chance of sarcasm or sunny with high expectations? A teacher's Language of Practice holds the key to creating a climate of mutual respect in our schools. This article will explore the power and promise of "teacher language," and how it can be used to…

  12. The relationship between vitamin D status and muscle strength in young healthy adults from sunny climate countries currently living in the northeast of Scotland.

    Science.gov (United States)

    Jamil, N A; Gray, S R; Fraser, W D; Fielding, S; Macdonald, H M

    2017-04-01

    The current study examined the relationship between vitamin D status and muscle strength in young healthy adults: residents (>6 months) and newcomers (0-3 months), originally from sunny climate countries but currently living in the northeast of Scotland. Our longitudinal data found a positive, albeit small, relationship between vitamin D status and knee extensor isometric strength.

  13. Understanding Non-Traditional PhD Students Habitus--Implications for PhD Programmes

    Science.gov (United States)

    Naidoo, Devika

    2015-01-01

    Against the background of vast changes in doctoral education and the emergence of non-traditional doctoral programmes, this paper investigates the habitus of non-traditional PhD students at a South African university. Bourdieu's conceptual tool of habitus informed the study. In-depth and open-ended interviews were conducted with 10 non-traditional…

  14. Kim e a literatura colonial de língua inglesa

    Directory of Open Access Journals (Sweden)

    Vanderlei J. Zacchi

    2016-01-01

    Full Text Available Kim é não apenas um dos livros mais importantes de Rudyard Kipling, mas ocupa também posição de destaque na literatura de língua inglesa. Foi lançado em 1901, quando a Índia, onde se passa o romance, era ainda uma possessão britânica e doze anos após Kipling, tendo nascido na Índia, haver migrado para a Inglaterra. As relações entre os personagens orientais e britânicos no romance sugerem uma visão estereotipada das diferenças raciais e culturais. A aná- lise dessas relações será feita, em primeiro lugar, a partir de uma contextualização da literatura colonial de língua inglesa. Kim se insere numa segunda etapa dessa literatura, na qual predominava um ponto de vista predominantemente britânico e que buscava afirmar a legitimidade do império. E, em segundo lugar, a partir do conceito de orientalismo, conforme desenvolvido por Edward Said (1995. Esse conceito demonstra como os ocidentais fazem uso de sínteses e estereótipos para descrever o Oriente e conceber visões autorizadas sobre ele. Palavras-chave: Rudyard Kipling; literatura colonial; orientalismo

  15. Molecular Cloning of phd1 and Comparative Analysis of phd1, 2, and 3 Expression in Xenopus laevis

    Directory of Open Access Journals (Sweden)

    Dandan Han

    2012-01-01

    Full Text Available Intensive gene targeting studies in mice have revealed that prolyl hydroxylase domain proteins (PHDs play important roles in murine embryonic development; however, the expression patterns and function of these genes during embryogenesis of other vertebrates remain largely unknown. Here we report the molecular cloning of phd1 and systematic analysis of phd1, phd2, and phd3 expression in embryos as well as adult tissues of Xenopus laevis. All three phds are maternally provided during Xenopus early development. The spatial expression patterns of phds genes in Xenopus embryos appear to define a distinct synexpression group. Frog phd2 and phd3 showed complementary expression in adult tissues with phd2 transcription levels being high in the eye, brain, and intestine, but low in the liver, pancreas, and kidney. On the contrary, expression levels of phd3 are high in the liver, pancreas, and kidney, but low in the eye, brain, and intestine. All three phds are highly expressed in testes, ovary, gall bladder, and spleen. Among three phds, phd3 showed strongest expression in heart.

  16. Research Collaboration and Commercialization: The PhD Candidate Perspective

    Science.gov (United States)

    Dooley, Lawrence; Kenny, Breda

    2015-01-01

    This paper explores PhD students' perceptions of their entrepreneurial and commercial capabilities, their attitude towards university supports and the extent to which they engage in external collaboration. The study concentrated on current PhD researchers at one university in Ireland as a unit of analysis and provides encouraging evidence from the…

  17. Tracking the PhD Students' Daily Computer Use

    Science.gov (United States)

    Sim, Kwong Nui; van der Meer, Jacques

    2015-01-01

    This study investigated PhD students' computer activities in their daily research practice. Software that tracks computer usage (Manic Time) was installed on the computers of nine PhD students, who were at their early, mid and final stage in doing their doctoral research in four different discipline areas (Commerce, Humanities, Health Sciences and…

  18. The Importance of Having a Ph.D., Career Advice

    Science.gov (United States)

    A presentation on the importance of having a PhD to motivate Initiative to Maximize Student Diversity Program (IMSD) undergrads towards conducting research, pursuing careers in the biomedical field, applying to grad school, and getting a Ph.D., based upon ARS scientist's experiences as a student, a ...

  19. Biomedical PhD education - an international perspective

    DEFF Research Database (Denmark)

    Mulvany, Michael J.

    2013-01-01

    tenured university positions. However, over the past 20–30 years, and particularly the past 10 years, the situation has changed dramatically. Governments in many countries have invested massively in PhD education, believing that trained researchers will contribute to the ‘knowledge society’, and thus...... increase the competitiveness of their countries in the future economies of the world. Thus, only a small fraction of PhD graduates now end up in academic research. Yet, the PhD remains a research degree, and indeed, institutions have become heavily dependent on PhD students for their research output...... during their PhD studies. The purpose of this article is to explore how this seeming paradox is being addressed in biomedicine and to show that far from being inconsistent that the two aspects are in fact complementary. The article is based on the author’s experience as Head of Aarhus Graduate School...

  20. ['Sandwich PhD': considerations for a successful experience abroad].

    Science.gov (United States)

    Salvetti, Marina de Goes; Bueno, Mariana; Gastaldo, Denise; Kimura, Amélia Fumiko; Pimenta, Cibele Andrucioli de Mattos

    2013-03-01

    International PhD internship, named "Sandwich PhD" in Brazil is an opportunity to improve research abilities, to become known in academic area and to establish and/or increase work opportunities in an international context. In this article, we describe key factors regarding the planning and development of the "Sandwich PhD" as experienced by professors and students involved in the collaboration between the School of Nursing, University of São Paulo and Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Canada. We also present the participation of PhD students' network as an alternative to the "Sandwich PhD". An international experience, when well-planned and developed correctly, promotes students' personal and professional development and favors the internationalization of Brazilian graduate programs and research groups.

  1. Lessons learned from 15 years of KIMS and 5 years of ACROSTUDY

    DEFF Research Database (Denmark)

    Luger, Anton; Feldt-Rasmussen, Ulla; Abs, Roger

    2011-01-01

    BACKGROUND: Pharmacoepidemiological surveys provide a valuable contribution to the continued monitoring of drug-related effects in patients with rare disorders. One of the earliest examples of this type of survey is KIGS (Pfizer International Growth Study Database), which has monitored the safety......, pharmacoepidemiological surveys such as KIMS and ACROSTUDY provide valuable information on the safety and effectiveness of treatment with GH replacement and pegvisomant in the real world.......-deficient adults for 15 years. Approximately 5 years ago, the ACROSTUDY database was established to monitor the long-term safety and effectiveness of pegvisomant in patients with acromegaly. CONCLUSIONS: By collecting data on the treatment of relatively rare conditions in routine clinical practice...

  2. Vapor-liquid phase equilibria of water modelled by a Kim-Gordon potential

    Energy Technology Data Exchange (ETDEWEB)

    Maerzke, K A; McGrath, M J; Kuo, I W; Tabacchi, G; Siepmann, J I; Mundy, C J

    2009-03-16

    Gibbs ensemble Monte Carlo simulations were carried out to investigate the properties of a frozen-electron-density (or Kim-Gordon, KG) model of water along the vapor-liquid coexistence curve. Because of its theoretical basis, such a KG model provides for seamless coupling to Kohn-Sham density functional theory for use in mixed quantum mechanics/molecular mechanics (QM/MM) implementations. The Gibbs ensemble simulations indicate rather limited transferability of such a simple KG model to other state points. Specifically, a KG model that was parameterized by Barker and Sprik to the properties of liquid water at 300 K, yields saturated vapor pressures and a critical temperature that are significantly under- and over-estimated, respectively.

  3. Lengua, escritura y arraigo en la obra de Kim Thúy

    Directory of Open Access Journals (Sweden)

    Lidia González Menéndez

    2014-04-01

    Full Text Available The writing of Kim Thúy, Quebec au thor originally from Vietnam, represents a place of attachment against exile. The protagonist in Ru(2009, her first work, rebuilds herself and builds her relationship with others in an autobiographical story where the tragic journey of the boat people articulates an almost intimate personal chronicle, which does not focus on exile but on rebirth and reconciliation. À toi(2011, which was written in tandem with Pascal Janovjak, author of Swiss nationality and French-Slovakian descent, is a hybrid work mixing epistolary novel and correspondence between writers across an ocean and six time zones. Even while staging the nomadism and exile of the co-authors, this work highlights the roots and represents writing as a celebration of words.

  4. KIM-1、CC16在急性肾/肺损伤临床诊断中的意义%The significance of KIM-1 、CC16 in acute kidney injury and acute lung injure

    Institute of Scientific and Technical Information of China (English)

    申晓丽; 周巧玲; 王祺

    2014-01-01

    目的 观察肾损伤分子-1(kidney injury molecule 1,KIM-1)与Clara细胞分泌蛋白(Clara cell secretionprotein,CCSP/CC16)在急性肾损伤(Acute Kidney Injury,AKI)合并急性肺损伤(Acute Lung Injury,ALI)患者体内的变化,探讨其在急性肾/肺损伤临床诊断中的意义.方法 入选本院确诊为AKI的患者纳入AKI组(25例),确诊为ALI的患者纳入ALI组(15例),确诊为AKI合并ALI的患者纳入AKI+ALI组(25例),与之年龄、性别、民族相匹配的非吸烟健康志愿者作为正常对照组(23例),采用酶联免疫吸附法(enzyme-linked immunosorbent assay,ELISA)检测尿液KIM-1、尿液CC16和血浆KIM-1、血浆CC16的水平,用比色法检测尿N-乙酰-β-D-氨基葡萄糖苷酶(N-acetyl-beta-D-glucosaminidase,NAG),整理四组所有研究资料利用统计学方法进行综合分析.结果 与正常非吸烟对照组相比,AKI组的尿NAG酶、尿KIM-1、血浆KIM-1和血浆CC16水平均显著升高,差异有统计学意义(P<0.05);ALI组的尿CC16和血浆CC16水平均显著升高,差异有统计学意义(P <0.05);AKI+ALI组的尿NAG酶、尿KIM-1、血浆KIM-1、尿CC16和血浆CC16水平均显著升高,差异有统计学意义(P<0.05).直线相关分析显示:AKI患者的尿KIM-1水平与尿NAG呈显著正相关关系(r=0.493,P<0.01),血浆KIM-1水平与尿NAG无直线相关关系(r =0.276,P>0.05).ALI患者的尿CC16、血浆CC16与氧合指数均呈显著负相关关系(r=0.460,P<0.01;r=0.468,P<0.01).AKI合并ALI患者的尿KIM-1、血浆KIM-1与尿CC16、血浆CC16均呈显著正相关关系(P<0.05).ROC曲线分析提示:在AKI诊断中,尿KIM-1曲线下面积为0.781(95% CI:0.688 ~0.875,P<0.01);血浆KIM-1曲线下面积为0.988(95% CI:0.000~1.000,P<0.01);尿NAG酶曲线下面积为0.798 (95%CI:0.708~0.888,P<0.01).在ALI诊断中,尿CC16曲线下面积为1.000(95% CI:1.000 ~1.000,P<0.01);血浆CC16曲线面积为0.849(95% CI:0.764~0.935,P<0.01).结论 AKI时尿NAG、尿KIM

  5. Launching a Geoscience Career: Insights Gained from MS PHD'S Beyond the PhD

    Science.gov (United States)

    Guzman, W. I.; Johnson, A.; Williamson Whitney, V.; Jansma, P. E.; Huggans, M. J.; Ricciardi, L.

    2013-05-01

    The Beyond the PhD (B-PhD) Professional Development Program is the newest addition to the Minorities Striving and Pursuing Higher Degrees of Success (MS PHD'S®) Professional Development Program in Earth System Science. This exciting new program is designed to facilitate the development of a new community of underrepresented minority (URM) doctoral candidates and recent doctorate degree recipients in Earth system science (ESS)-related fields. Building upon MS PHD'S extensive professional development activities provided to URM undergraduate and graduate students, B-PhD's vision is to encourage and support URM doctoral students and early career PhD's in becoming part of the global workforce. (Since its inception in 2003, MSPHD'S supports 213 participants of which 42 have achieved the doctoral degree and another 71 are enrolled in doctoral programs.) By providing customized support and advocacy for participants, B-PhD facilitates smoother and informed transitions from graduate school to postdoctoral and tenure-track positions, as well as other "first" jobs in academia, government, industry, and non-profit organizations. In 2011, the first conference for 18 doctoral candidate and recent graduates was hosted at the University of Texas at Arlington's (UTA) College of Science. Using a format of guest speakers, brown bag discussions, and interactive breakout sessions, participants engaged in sessions entitled "Toolkits for Success in Academia, Business and Industry, Federal Government and Non-Profits", "Defining Short, Mid and Long Term Career Goals", "Accessing and Refining Skill Sets and Other Door Openers", "International Preparation and Opportunities", "Paying it Forward/Lifting as You Climb", and "Customized Strategies for Next Steps". This presentation will discuss outcomes from this pilot project, the use of social media to track and support ongoing B-PhD activities, and objectives for future B-PhD workshops.

  6. Italia-Netherland PhD Program: the I.O. PhD Research Program.

    Science.gov (United States)

    Bellissima, Valentina; Borghesi, Alessandro; Bozzetti, Valentina; Dessì, Angelica; Fabiano, Adele; Risso, Francesco M; Salvo, Vincenzo; Satriano, Angela; Silvagni, Davide; Varrica, Alessandro; van Bel, Frank; Visser, Gerard H A; Vles, Hans Js; Zimmermann, Luc J I; Gavilanes, Antonio D W; Gazzolo, Diego

    2011-10-01

    In the framework of long-term scientific collaboration among the founder members coming from Holland and Italy there was a growing consensus to activate a philosophical doctorate (PhD) program, involving young Italian researchers in the field of perinatal medicine, neonatology and pediatrics. The aims were to promote excellence in research, offering to young Italian physicians the opportunity to maturate an International research experience leading to PhD degree, and to promote human and technological improvement energies in perinatal, neonatal and pediatrics research. Thus, an official collaboration among the Dutch Universities from Maastricht and Utrecht and the Italian Children's Hospital from Alessandria, has been activated on March 1st 2010, finalized to the PhD program. The experimental phase included the selection of projects and relative candidates after an interview-selection focusing on their scientific attitudes and the availability on their research projects. Candidates' selection started on May 2010 and on September 29th ten projects and candidates have been approved by the scientific commission. Research topics included: perinatal asphyxia, aging and the origin of adulthood neurodegenerative disease, neuroprotective strategies, biochemical pulmonology, intrauterine growth retardation and perinatal teratology. To date, all projects have been approved by local Ethics Committee from the University/Hospital of origin of the candidates. Five manuscripts have been published and/or submitted to international Journals regarding pneumology, perinatal asphyxia and teratology, whilst about 60-70% of data regarding clinical studies have already been collected.

  7. Logistički kontroling u savremenim logističkim sistemima / Logistic controlling in modern logistic systems

    Directory of Open Access Journals (Sweden)

    Aleksandar Cakić

    2003-01-01

    Full Text Available U raduje data definicija logističkog kontrolinga u logističkim sistemima Prikazane su njegove osnovne funkcije, kao i mesto i uloga u upravljanju savremenim logističkim sistemima. Pregledno je prikazano kako pojedini autori definišu pojam i funkcije logističkog kontrolinga u savremenim logističkim sistemima. / In this paper a definition of logistic controlling in logistic systems has been given. The basic functions of logistic controlling are shown as well as its place and role in managing modern logistic systems. It is clearly shown how some other authors define the notion and the functions of logistic controlling in modern logistic systems.

  8. The impact of silicon solar cell architecture and cell interconnection on energy yield in hot & sunny climates

    KAUST Repository

    Haschke, Jan

    2017-03-23

    Extensive knowledge of the dependence of solar cell and module performance on temperature and irradiance is essential for their optimal application in the field. Here we study such dependencies in the most common high-efficiency silicon solar cell architectures, including so-called Aluminum back-surface-field (BSF), passivated emitter and rear cell (PERC), passivated emitter rear totally diffused (PERT), and silicon heterojunction (SHJ) solar cells. We compare measured temperature coefficients (TC) of the different electrical parameters with values collected from commercial module data sheets. While similar TC values of the open-circuit voltage and the short circuit current density are obtained for cells and modules of a given technology, we systematically find that the TC under maximum power-point (MPP) conditions is lower in the modules. We attribute this discrepancy to additional series resistance in the modules from solar cell interconnections. This detrimental effect can be reduced by using a cell design that exhibits a high characteristic load resistance (defined by its voltage-over-current ratio at MPP), such as the SHJ architecture. We calculate the energy yield for moderate and hot climate conditions for each cell architecture, taking into account ohmic cell-to-module losses caused by cell interconnections. Our calculations allow us to conclude that maximizing energy production in hot and sunny environments requires not only a high open-circuit voltage, but also a minimal series-to-load-resistance ratio.

  9. 2. mednarodna konferenca My PhD = 2nd My phd International Conference

    Directory of Open Access Journals (Sweden)

    Armand Faganel

    2008-09-01

    Full Text Available The article presents the organization of the second My phd InternationalConference organized in June in Bratislava. The organizer Friedrich Ebert Foundation is a German non-profit organization. During the conference young researchers from various fields dealt with the issue of ‘New Europe’ and the challenges of sustainable development. The conference was also an opportunity for young researchers to meet new colleagues and exchange their views. The interest was very big since only 40 percent of the applicants were accepted. Another interesting thing was the competitive approach towards the conference, which means that only the best articles will be published in the conference proceedings.

  10. Question Utilization in Solution-Focused Brief Therapy: A Recursive Frame Analysis of Insoo Kim Berg's Solution Talk

    Science.gov (United States)

    Cotton, Jeffrey

    2010-01-01

    Recursive frame analysis (RFA) was used to conduct a single case investigation of Insoo Kim Berg's question utilization talk in a solution-focused brief therapy (SFBT) session. Due to the lack of process research that explores how SFBT questions facilitate change, the author investigated how Berg's solution language influenced a client to respond…

  11. Language and Family Dispersion: North Korean Linguist Kim Su-gyŏng and the Korean War

    Directory of Open Access Journals (Sweden)

    Ryuta Itagaki

    2017-03-01

    Full Text Available This article analyzes the unpublished memoir of Kim Su-gyŏng (1918–2000, a linguist who was active in North Korea from the mid-1940s until the late 1960s, and situates his account of his experience of the Korean War within the context of his linguistic essays and correspondence. In doing so, the article considers the role that the personal and the social play in language, utilizing Saussure’s theoretical framework, with which Kim himself was well versed. Kim wrote his memoirs in the 1990s to his family, from whom he had become separated during the Korean War and who now lived in Toronto. In this text, he writes in “personal” language that reveals his uncertainty and his feelings for his family, but then immediately negates these feelings through the use of “social” language, which resonates with his interpretation of the linguistic thesis that Josef Stalin developed during the Korean War on language and national identity. For Kim, the relationship between language and nation was not at all self-evident, but something that he idealized in response to the dispersal of his family. By offering a reflexive reading of a memoir written by a North Korean linguist, this article makes a breakthrough in the investigation of North Korean wartime academic history, which has not risen above the level of analyzing articles in the field of linguistics that were published at the time.

  12. Brenda K. Edwards, PhD | DCCPS/NCI/NIH

    Science.gov (United States)

    Brenda K. Edwards, PhD, has been with the Surveillance Research Program (SRP) and its predecessor organizations at the National Cancer Institute (NCI) since 1989, serving as SRP’s Associate Director from 1990-2011.

  13. Meet EPA Scientist Michael Nye, Ph.D.

    Science.gov (United States)

    Michael Nye, Ph.D., is a social scientist who studies natural risk, socio-demographic change and sustainable behavior. Prior to joining EPA, he worked for the UK Environment Agency in flood risk management and emergency preparedness

  14. ebibliographical compilation of phd theses produced at the faculty of ...

    African Journals Online (AJOL)

    USER

    2015-06-01

    Jun 1, 2015 ... This paper attempts to provide a systematic list of Ph.D theses produced by the. Faculty of Science ... field of library and information science the concept of bibliography .... Information System (GIS) in Kano State,. Nigeria.

  15. Meet EPA Engineer Shawn Ryan, Ph.D.

    Science.gov (United States)

    Shawn Ryan, Ph.D. is a chemical engineer at EPA's National Homeland Security Research Center. He has worked at EPA for 12 years, nine of which have been devoted to leading research to support decontamination and consequence management.

  16. Meet EPA Scientist Tim Shafer, Ph.D.

    Science.gov (United States)

    Tim Shafer earned his bachelor’s degree in biology and chemistry from Hope College in Holland, MI, in 1986 and his Ph.D. in pharmacology and environmental toxicology from Michigan State University in 1991.

  17. Meet EPA Scientist Susan Yee, Ph.D.

    Science.gov (United States)

    Susan Yee, Ph.D., is an ecologist at EPA's Gulf Ecology Division. She is working on the Puerto Rico Sustainable Communities program, developing decision support tools to evaluate how alternative decisions impact coastal ecosystem goods and services

  18. Meet EPA Chemist Quincy Teng, Ph.D.

    Science.gov (United States)

    EPA research chemist Quincy Teng, Ph.D., focuses on the application of metabolomics—a relatively new, specialized field of biochemistry focused on studying small molecules known as metabolites—on environmental and life sciences.

  19. Vertical changes in the probability distribution of downward irradiance within the near-surface ocean under sunny conditions

    Science.gov (United States)

    Gernez, Pierre; Stramski, Dariusz; Darecki, Miroslaw

    2011-07-01

    Time series measurements of fluctuations in underwater downward irradiance, Ed, within the green spectral band (532 nm) show that the probability distribution of instantaneous irradiance varies greatly as a function of depth within the near-surface ocean under sunny conditions. Because of intense light flashes caused by surface wave focusing, the near-surface probability distributions are highly skewed to the right and are heavy tailed. The coefficients of skewness and excess kurtosis at depths smaller than 1 m can exceed 3 and 20, respectively. We tested several probability models, such as lognormal, Gumbel, Fréchet, log-logistic, and Pareto, which are potentially suited to describe the highly skewed heavy-tailed distributions. We found that the models cannot approximate with consistently good accuracy the high irradiance values within the right tail of the experimental distribution where the probability of these values is less than 10%. This portion of the distribution corresponds approximately to light flashes with Ed > 1.5?, where ? is the time-averaged downward irradiance. However, the remaining part of the probability distribution covering all irradiance values smaller than the 90th percentile can be described with a reasonable accuracy (i.e., within 20%) with a lognormal model for all 86 measurements from the top 10 m of the ocean included in this analysis. As the intensity of irradiance fluctuations decreases with depth, the probability distribution tends toward a function symmetrical around the mean like the normal distribution. For the examined data set, the skewness and excess kurtosis assumed values very close to zero at a depth of about 10 m.

  20. Structural insight into histone recognition by the ING PHD fingers.

    Science.gov (United States)

    Champagne, Karen S; Kutateladze, Tatiana G

    2009-05-01

    The Inhibitor of Growth (ING) tumor suppressors are implicated in oncogenesis, control of DNA damage repair, cellular senescence and apoptosis. All members of the ING family contain unique amino-terminal regions and a carboxy-terminal plant homeodomain (PHD) finger. While the amino-terminal domains associate with a number of protein effectors including distinct components of histone deacetylase (HDAC) and histone acetyltransferase (HAT) complexes, the PHD finger binds strongly and specifically to histone H3 trimethylated at lysine 4 (H3K4me3). In this review we describe the molecular mechanism of H3K4me3 recognition by the ING1-5 PHD fingers, analyze the determinants of the histone specificity and compare the biological activities and structures within subsets of PHD fingers. The atomic-resolution structures of the ING PHD fingers in complex with a H3K4me3 peptide reveal that the histone tail is bound in a large and deep binding site encompassing nearly one-third of the protein surface. An extensive network of intermolecular hydrogen bonds, hydrophobic and cation-pi contacts, and complementary surface interactions coordinate the first six residues of the H3K4me3 peptide. The trimethylated Lys4 occupies an elongated groove, formed by the highly conserved aromatic and hydrophobic residues of the PHD finger, whereas the adjacent groove accommodates Arg2. The two grooves are connected by a narrow channel, the small size of which defines the PHD finger's specificity, excluding interactions with other modified histone peptides. Binding of the ING PHD fingers to H3K4me3 plays a critical role in regulating chromatin acetylation. The ING proteins function as tethering molecules that physically link the HDAC and HAT enzymatic complexes to chromatin. In this review we also highlight progress recently made in understanding the molecular basis underlying biological and tumorigenic activities of the ING tumor suppressors.

  1. SCREENING OF PRESCHOOL CHILDREN FOR BLOOD LEAD LEVELS AT KIMS HOSPITAL

    Directory of Open Access Journals (Sweden)

    Chandrakala

    2014-03-01

    Full Text Available OBJECTIVE: to screen preschool children for blood lead level with an objective to estimate ZPP levels among preschool children attending OPD and admitted to wards and to confirm blood lead levels in children whose ZPP is>_35ugm/dl. METHODS: hospital based descriptive study conducted at KIMS, BANGALORE from 1st July 2007 to 31st July 2008. 100 preschool children aged between 1 to 6 years who came to OPD and were admitted, were chosen randomly. Data was collected in a simple questionnaire which included demographic, clinical, investigations. Venous blood, 2 ml was drawn and estimated for ZPP. If ZPP >_ 35ugm/dl, then blood samples were estimated for blood lead levels. The data collected in this study was analyzed statistically using chi square test and standard normal variate (Z test for proportions. RESULTS: Out of 100 children, 37% of them had ZPP > 35 ugm/dl .Among these 20% had blood level more >10ugm/dl. Socio economic status affects lead exposure with poor socio economic status group being most prone for lead absorption. Among the 20% who had blood lead levels >10 ugm/dl, 15% of them belonged to urban area and 5% belonged to rural area. Location of the house of children in this study was observed that in industrial area were 85%, mechanic factory were 7%, battery factory were 3%, automobile and cottage industry were 2% . Among 100 children, 57 had hemoglobin % of > 10 gm and 43 were anemic having hemoglobin <10 gm%. CONCLUSION: As lead poisoning patients can be asymptomatic or symptomatic with only vague presentations, screening of blood lead levels should be made as a routine investigation. Awareness should be created regarding the sources of lead, its exposure and potential health effects

  2. Sunny Norton Sound

    Science.gov (United States)

    2002-01-01

    A clear day over Norton Sound in the Bering Sea allowed SeaWiFS to capture this image of the phytoplankton bloom off the coast of Alaska. Credit: Provided by the SeaWiFS Project, NASA/Goddard Space Flight Center, and ORBIMAGE

  3. Surgical technique for single-port laparoscopy in huge ovarian tumors: SW Kim's technique and comparison to laparotomy.

    Science.gov (United States)

    Kim, Jeong Sook; Lee, In Ok; Eoh, Kyung Jin; Chung, Young Shin; Lee, Inha; Lee, Jung-Yun; Nam, Eun Ji; Kim, Sunghoon; Kim, Young Tae; Kim, Sang Wun

    2017-03-01

    This study aimed to introduce a method to remove huge ovarian tumors (≥15 cm) intact with single-port laparoscopic surgery (SPLS) using SW Kim's technique and to compare the surgical outcomes with those of laparotomy. Medical records were retrospectively reviewed for patients who underwent either SPLS (n=21) with SW Kim's technique using a specially designed 30×30-cm(2)-sized 3XL LapBag or laparotomy (n=22) for a huge ovarian tumor from December 2008 to May 2016. Perioperative surgical outcomes were compared. In 19/21 (90.5%) patients, SPLS was successfully performed without any tumor spillage or conversion to multi-port laparoscopy or laparotomy. There was no significant difference in patient characteristics, including tumor diameter and total operation time, between both groups. The postoperative hospital stay was significantly shorter for the SPLS group than for the laparotomy group (median, 2 [1 to 5] vs. 4 [3 to 17] days; Phuge ovarian tumors.

  4. A KIM-compliant potfit for fitting sloppy interatomic potentials: Application to the EDIP model for silicon

    CERN Document Server

    Wen, Mingjian; Brommer, Peter; Elliott, Ryan S; Sethna, James P; Tadmor, Ellad B

    2016-01-01

    Fitted interatomic potentials are widely used in atomistic simulations thanks to their ability to compute the energy and forces on atoms quickly. However, the simulation results crucially depend on the quality of the potential being used. Force matching is a method aimed at constructing reliable and transferable interatomic potentials by matching the forces computed by the potential as closely as possible, with those obtained from first principles calculations. The potfit program is an implementation of the force-matching method that optimizes the potential parameters using a global minimization algorithm followed by a local minimization polish. We extended potfit in two ways. First, we adapted the code to be compliant with the KIM Application Programming Interface (API) standard (part of the Knowledgebase of Interatomic Models Project). This makes it possible to use potfit to fit many KIM potential models, not just those prebuilt into the potfit code. Second, we incorporated the geodesic Levenberg--Marquardt...

  5. The Production Rate and Employment of Ph.D. Astronomers

    CERN Document Server

    Metcalfe, Travis S

    2007-01-01

    In an effort to promote self-regulation of the astronomy job market, I examine the supply of, and demand for, astronomers over time. On the supply side, I document the production rate of Ph.D. astronomers from 1970 to 2006 using the UMI Dissertation Abstracts database, along with data from other independent sources. I compare the long-term trends in Ph.D. production with federal astronomy research funding over the same time period, and I demonstrate that additional funding is correlated with higher subsequent Ph.D. production. On the demand side, I monitor the changing patterns of employment using statistics about the number and types of jobs advertised in the AAS Job Register from 1984 to 2006. Finally, I assess the sustainability of the job market by normalizing this demand by the annual Ph.D. production. The most recent data suggest that there are now annual advertisements for about one postdoctoral job, half a faculty job, and half a research/support position for every new domestic Ph.D. recipient in astr...

  6. The Production Rate and Employment of Ph.D. Astronomers

    Science.gov (United States)

    Metcalfe, Travis S.

    2008-02-01

    In an effort to encourage self-regulation of the astronomy job market, I examine the supply of, and demand for, astronomers over time. On the supply side, I document the production rate of Ph.D. astronomers from 1970 to 2006 using the UMI Dissertation Abstracts database, along with data from other independent sources. I compare the long-term trends in Ph.D. production with federal astronomy research funding over the same time period, and I demonstrate that additional funding is correlated with higher subsequent Ph.D. production. On the demand side, I monitor the changing patterns of employment using statistics about the number and types of jobs advertised in the AAS Job Register from 1984 to 2006. Finally, I assess the sustainability of the job market by normalizing this demand by the annual Ph.D. production. The most recent data suggest that there are now annual advertisements for about one postdoctoral job, half a faculty job, and half a research/support position for every new domestic Ph.D. recipient in astronomy and astrophysics. The average new astronomer might expect to hold up to 3 jobs before finding a steady position.

  7. A KIM-compliant potfit for fitting sloppy interatomic potentials: application to the EDIP model for silicon

    Science.gov (United States)

    Wen, Mingjian; Li, Junhao; Brommer, Peter; Elliott, Ryan S.; Sethna, James P.; Tadmor, Ellad B.

    2017-01-01

    Fitted interatomic potentials are widely used in atomistic simulations thanks to their ability to compute the energy and forces on atoms quickly. However, the simulation results crucially depend on the quality of the potential being used. Force matching is a method aimed at constructing reliable and transferable interatomic potentials by matching the forces computed by the potential as closely as possible, with those obtained from first principles calculations. The potfit program is an implementation of the force-matching method that optimizes the potential parameters using a global minimization algorithm followed by a local minimization polish. We extended potfit in two ways. First, we adapted the code to be compliant with the KIM Application Programming Interface (API) standard (part of the Knowledgebase of Interatomic Models project). This makes it possible to use potfit to fit many KIM potential models, not just those prebuilt into the potfit code. Second, we incorporated the geodesic Levenberg-Marquardt (LM) minimization algorithm into potfit as a new local minimization algorithm. The extended potfit was tested by generating a training set using the KIM environment-dependent interatomic potential (EDIP) model for silicon and using potfit to recover the potential parameters from different initial guesses. The results show that EDIP is a ‘sloppy model’ in the sense that its predictions are insensitive to some of its parameters, which makes fitting more difficult. We find that the geodesic LM algorithm is particularly efficient for this case. The extended potfit code is the first step in developing a KIM-based fitting framework for interatomic potentials for bulk and two-dimensional materials. The code is available for download via https://www.potfit.net.

  8. Evaluation of medium-range weather forecasts about Korea Institute of Atmospheric Prediction Systems (KIAPS) Integrated Model System (KIM)

    Science.gov (United States)

    Lee, J.; Seol, K. H.

    2015-12-01

    The Korea Institute of Atmospheric Prediction Systems (KIAPS) is a government funded non-profit research and development institute located in Seoul, South Korea. KIAPS was established in 2011 by the Korea Meteorological Administration, KIAPS' primary sponsor. KIAPS is developing the KIAPS Integrated Model System (KIM), a backbone for the next-generation operational global numerical weather prediction (NWP) system. The KIM will be a unified model that can be used for global modeling as well as local areas, particularly optimized to topographic and meteorological features of the Korean Peninsula. We have been completed developing major model components based on KIAPS own research and release the KIAPS beta version model on September 2014. We evaluated the results of KIM by using verification system developed KIAPS, it is composed of standard verification score based on WMO report. The system consists of four parts: verification against analysis, observations, vertical verification and quantitative precipitation forecasts. The results of verification against analysis, we found that increase of error for temperature under 700 hPa. In case of MSLP, poor performance except for tropical region is represented, and the increase of error for geopotential height is shown in tropical region. For verification against observations, positive bias is represented for upper level geopotential height, for low level wind speed in tropical region in summer, for all level wind speed in Northern Hemisphere in winter, and for specific humidity in Northern Hemisphere in summer. As previously stated about the result against analysis, cold bias for low level temperature is shown in Northern Hemisphere in summer. In case of verification for rain about KIM, the model value is underestimated in heavy rain category in summer, on the contrary, that is overestimated in heavy rain category in winter. Overall, there is overestimation in ocean for all models. Our findings indicate that continuing

  9. A new record of Cleantioides emarginata Kwon & Kim,1992 (Crustacea, Isopoda, Valvifera) from Changjiang River estuary, China

    Institute of Scientific and Technical Information of China (English)

    LIU Wenliang; Gary C.B.POORE

    2013-01-01

    At present,descriptions of Cleantioides emarginata Kwon & Kim,1992 have been limited to the type locality of Pusan,Korea.In this study,we discovered this species in the Changjiang (Yangtze) River estuary,China.This represents an extension of the known geographical range of C.emarginata.In addition,we present information of a colour pattern not previously described,along with details on the estuarine habitat of the species.

  10. North Korean Leadership Dynamics and Decision-making under Kim Jong-un: A First Year Assessment

    Science.gov (United States)

    2013-09-01

    nuclear deterrent” up for discussion unless it is in the context of Korean Peninsula-wide denuclearization —code for securing a peace treaty with the...achieve denuclearization on the Korean Peninsula. This latter point of describ- ing its nuclear capability as necessary to achieve denuclearization is an...ar- gument that Pyongyang never made under Kim Jong-il. Instead, North Korea claimed it would need a nuclear deterrent until denuclearization had

  11. Tesi di dottorato PhD Dissertations

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2000-06-01

    Full Text Available

    Segnalazione di tesi di dottorato.

     

    Miguel Calleja Puerta

    El conde Suero Vermúdez, su parentela y su entorno social. La aristocracia leonesa en los siglos XI y XII, Tesis de doctorado en Historia, Universidad de Oviedo (España, 2000

     

    Adele Cilento

    Potere e monachesimo nella Calabria bizantina: relazioni e interferenze (secc. IX-XI, Tesi di dottorato di ricerca in Storia medievale (X ciclo, Università degli Studi di Torino, 2000

     

    Amedeo De Vincentiis

    Firenze e i signori. Sperimentazioni istituzionali e modelli di regime nelle signorie fiorentine degli Angioini (fine XIII - metà XIV secolo, Tesi di dottorato di ricerca in Storia medioevale (XI ciclo, Università degli Studi di Milano, 1999

     

    Marco Folin

    Il sistema politico di un antico Stato italiano: i ducati estensi nella prima Età moderna (1452-1598, Tesi di dottorato di ricerca in Storia, Scuola Normale superiore di Pisa, 2000

     

    Barbara Frale

    Guardiani del Santuario. Le radici orientali del processo contro l’ordine del Tempio (1128 - 1314, Tesi di dottorato di ricerca in Storia sociale d’Europa (XI ciclo, Università "Ca’ Foscari" di Venezia, 2000

    Report of PhD Dissertations.

     

    Miguel Calleja Puerta

    El conde Suero Vermúdez, su parentela y su entorno social. La aristocracia leonesa en los siglos XI y XII, Tesis de doctorado en Historia, Universidad de Oviedo (España, 2000

     

    Adele Cilento

    Potere e monachesimo nella Calabria bizantina: relazioni e interferenze (secc. IX-XI, Tesi di dottorato di ricerca in Storia medievale (X ciclo, Università degli Studi di Torino, 2000

     

    Amedeo De Vincentiis

    Firenze e

  12. Dido3 PHD Modulates Cell Differentiation and Division

    Directory of Open Access Journals (Sweden)

    Jovylyn Gatchalian

    2013-07-01

    Full Text Available Death Inducer Obliterator 3 (Dido3 is implicated in the maintenance of stem cell genomic stability and tumorigenesis. Here, we show that Dido3 regulates the expression of stemness genes in embryonic stem cells through its plant homeodomain (PHD finger. Binding of Dido3 PHD to histone H3K4me3 is disrupted by threonine phosphorylation that triggers Dido3 translocation from chromatin to the mitotic spindle. The crystal structure of Dido3 PHD in complex with H3K4me3 reveals an atypical aromatic-cage-like binding site that contains a histidine residue. Biochemical, structural, and mutational analyses of the binding mechanism identified the determinants of specificity and affinity and explained the inability of homologous PHF3 to bind H3K4me3. Together, our findings reveal a link between the transcriptional control in embryonic development and regulation of cell division.

  13. An analysis of Ph.D. examiners' reports in engineering

    Science.gov (United States)

    Prieto, Elena; Holbrook, Allyson; Bourke, Sid

    2016-03-01

    In recent years, there have been increasing calls for an overall transformation of the nature of engineering Ph.D. programs and the way theses are assessed. There exists a need to understand the examination process to ensure the best quality outcome for candidates in engineering. The work we present in this paper uses data collected between 2003 and 2010 for a total of 1220 Australian Ph.D. theses by analysing examiner reports. Our analysis indicates that Ph.D. theses in engineering, N = 106, differ considerably from those in other fields in areas such as gender of candidates and examiners and the examiners' geographical location. We also found that assessment areas such as significance and contribution of the thesis, publications arising from the thesis, breadth, depth and recency of the literature review and communication and editorial correctness are areas in which the proportion of text of engineering examiners' comments differs significantly from other fields.

  14. Mid-Career PhD Physicists: Academia & Beyond

    Science.gov (United States)

    White, Susan

    2017-01-01

    What jobs do mid-career PhD physicists hold? In a first-ever study, we collected data in 2011 from over 1,500 physics PhD recipients from the classes of 1996, 1997, 2000, and 2001. About 45% of the physics PhD recipients in these classes immediately took jobs that were not temporary, and over 40% accepted postdocs. How does taking a postdoc affect mid-career employment? What is the relationship between first job (after any postdocs) and mid-career employment? How do physicists' actual jobs compare with what they thought they would be doing when they graduated? Using our initial employment and mid-career data, I will answer these questions and more.

  15. Enhancing the skills of PhD supervisors facing internationalization

    DEFF Research Database (Denmark)

    Bøgelund, Pia

    2013-01-01

    This research started out due to some institutional changes at a department at Aalborg University as regards supervision of PhD students. For various reasons the department suddenly got a large intake of PhD students in 2008, many of which came with an international background. After a period...... of time staff members of the department began to look very frustrated. Not only did they feel burdened with the large intake, they also struggled with the task of facilitating the transition of international students to become independent scholars. The situation led to the creation of a more general...... interview study within the faculty, and an inquiry into the field of cross-cultural supervision with the purpose of enhancing the skills of PhD supervisors. As is often the case with cross-cultural exchange and inquiry, the study ended up by being just as informative on the supervision cultures and settings...

  16. Lactobacillus curvatus WiKim38 isolated from kimchi induces IL-10 production in dendritic cells and alleviates DSS-induced colitis in mice.

    Science.gov (United States)

    Jo, Sung-Gang; Noh, Eui-Jeong; Lee, Jun-Young; Kim, Green; Choi, Joo-Hee; Lee, Mo-Eun; Song, Jung-Hee; Chang, Ji-Yoon; Park, Jong-Hwan

    2016-07-01

    Probiotics such as lactobacilli and bifidobacteria have healthpromoting effects by immune modulation. In the present study, we examined the immunomodulatory properties of Lactobacillus curvatus WiKim38, which was newly isolated from baechu (Chinese cabbage) kimchi. The ability of L. curvatus WiKim38 to induce cytokine production in bone marrow-derived dendritic cells (BMDCs) was determined by enzyme-linked immunosorbent assay. To evaluate the molecular mechanisms underlying L. curvatus Wikim38-mediated IL-10 production, Western blot analyses and inhibitor assays were performed. Moreover, the in vivo anti-inflammatory effects of L. curvatus WiKim38 were examined in a dextran sodium sulfate (DSS)-induced colitis mouse model. L. curvatus WiKim38 induced significantly higher levels of IL-10 in BMDCs compared with that induced by LPS. NF-κB and ERK were activated by L. curvatus WiKim38, and an inhibitor assay revealed that these pathways were required for L. curvatus WiKim38-induced production of IL-10 in BMDCs. An in vivo experiment showed that oral administration of L. curvatus WiKim38 increased the survival rate of mice with DSS-induced colitis and improved clinical signs and histopathological severity in colon tissues. Taken together, these results indicate that L. curvatus Wikim38 may have health-promoting effects via immune modulation, and may thus be applicable for therapy of various inflammatory diseases.

  17. Drug screening in urine by cloned enzyme donor immunoassay (CEDIA) and kinetic interaction of microparticles in solution (KIMS): a comparative study.

    Science.gov (United States)

    Schwettmann, Lutz; Külpmann, Wolf-Rüdiger; Vidal, Christian

    2006-01-01

    Two commercially available drug-screening assays were evaluated: the Roche kinetic interaction of microparticles in solution (KIMS) assay and the Microgenics cloned enzyme donor immunoassay (CEDIA). Urine samples from known drug-abuse patients were analyzed for amphetamines, barbiturates, benzodiazepines, benzoylecgonine, cannabinoids, LSD, methadone and opiates. Samples with discordant findings for the two assays were analyzed by gas chromatography/mass spectrometry (GC/MS) or gas chromatography/electron capture detection (GC/ECD). Amphetamines showed 96.0% concordant results, with two false positive findings by CEDIA, three by KIMS and a further two false negatives by KIMS. Barbiturates showed 99.4% concordant results, with one false negative by KIMS. Benzodiazepines showed 97.4% concordant results, with two false negatives by KIMS (cutoff 100 microg/L, CEDIA cutoff 300 microg/L). Benzoylecgonine showed 17.8% concordant positive and 82.2% concordant negative results and no false finding by either assay. Cannabinoids showed 99.3% concordant results, with one sample negative by KIMS at a cutoff of 50 microg/L and positive by CEDIA (cutoff 25 microg/L). For LSD, 6.7% of findings were not in agreement. Methadone showed 97.5% concordant results, with two false positives by CEDIA, and one false positive and one false negative by KIMS. Opiates showed 96.9% concordant results, with no false KIMS results, but four false positives by CEDIA. The results indicate that the agreement of the CEDIA and KIMS results for the eight drugs is rather good (93.3-100%).

  18. PhD Dissertations Tesi di dottorato

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2004-06-01

    Full Text Available

    Report of PhD Dissertations.

    Francesco Barone

    Istituzioni, società ed economia a Catania nel tardo medioevo (XIV-XV secolo, Tesi di dottorato in Storia medievale (XVI ciclo, Università degli Studi di Firenze, 2004

     

    Laura Berti Ceroni

    Il territorio e le strutture di Cesarea e Classe tra tarda antichità e alto medioevo in rapporto con Ravenna, Tesi di dottorato di ricerca in Storia e Informatica, Università degli studi di Bologna, 2002-2003.

     

    Marco Bicchierai

    Poppi dalla signoria dei conti Guidi al vicariato del Casentino (1360-1480, Tesi di dottorato in Storia medievale (XIV ciclo, Università degli Studi di Firenze, 2004

     

    Emanuela Garimberti

    Spatiosa ad habitandum loca. Luoghi e identità nella Historia Langobardorum di Paolo Diacono, Tesi di dottorato in Storia medievale (XV ciclo, Università degli Studi di Bologna, 2004

     

    Lorenzo Tanzini

    Sistemi normativi e pratiche istituzionali a Firenze dalla fine del XIII all’inizio del XV secolo, Tesi di dottorato di ricerca in Storia medievale (XVI ciclo, Università degli Studi di Firenze, 2004

     

    Stefania Tarquini

    Pellegrinaggio e asseto urbano di Roma, Tesi di dottorato di ricerca in Storia dei centri, delle vie e della cultura dei pellegrinaggi nel Medioevo euro mediterraneo (XV ciclo, Università degli studi di Lecce, 2003

    Segnalazione di tesi di dottorato.

    Francesco Barone

    Istituzioni, società ed economia a Catania nel tardo medioevo (XIV-XV secolo, Tesi di dottorato in Storia medievale (XVI ciclo, Università degli Studi di Firenze, 2004

     

    Laura Berti Ceroni

  19. PhD Dissertations Tesi di dottorato

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2004-12-01

    Full Text Available

    Report of PhD Dissertations.

    Massimo Della Misericordia

    Divenire comunità. Comuni rurali, poteri signorili, identità sociali in Valtellina e nella montagna lombarda nel tardo medioevo, Tesi di dottorato in Storia medievale (XIV ciclo, Università degli Studi di Torino, 2003

     

    Mariano Dell’Omo

    Il monastero di S. Liberatore alla Maiella centro dell’irradiazione di Montecassino nell’Abruzzo medievale e moderno. Contributo alla storia dell’organizzazione patrimoniale e della civiltà monastica cassinese nell’Italia centrale attraverso i documenti di S. Liberatore conservati nell’Archivio di Montecassino. Introduzione storica, paleografica e archivistica. Edizione dei documenti più antichi (†798-1000 e regesti di quelli posteriori (1005-1735, Tesi di dottorato in Storia Ecclesiastica, Facoltà di Storia Ecclesiastica, Pontificia Università Gregoriana di Roma,  2004

     

    Giulia Lorenzoni

    Conquistare e governare la città. Forme di potere e istituzioni nel primo anno della signoria viscontea a Bologna (ottobre 1350-novembre 1351, Tesi di dottorato in Storia medievale (XVI ciclo, Università degli Studi di Bologna, 2004

     

    Federica Monteleone

    Il viaggio di Carlo Magno in Terra Santa. Un’esperienza di pellegrinaggio nella tradizione europea occidentale, Tesi di dottorato di ricerca in Storia dei centri, delle vie e della cultura dei pellegrinaggi nel Medioevo euro mediterraneo (XV ciclo

     

    Francesca Pucci Donati

    Fra teorie mediche e pratica quotidiana: i calendari dietetici dell’Occidente latino altomedievale (secoli IX-XI, Tesi di dottorato di ricerca in Storia medievale (XV ciclo, Università degli studi di Bologna, 2004

    Alberto Ricciardi

    L’Epistolario di Lupo

  20. PhD Dissertations Tesi di dottorato

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2002-06-01

    Full Text Available

    Report of PhD dissertation.

    Laura Baietto

    Una politica per le città. Rapporti fra papato, vescovi e comuni nell'Italia centro-settentrionale da Innocenzo III a Gregorio IX, Tesi di dottorato di ricerca in Storia Medievale, Università degli Studi di Torino, 2002

     

    Giuseppe Banfo

    Compresenze e sovrapposizioni di poteri territoriali di qualità diversa tra X e XIII: il caso del basso Monferrato, Tesi di dottorato di ricerca in Storia medievale, Università degli Studi di Torino, 2002

     

    Francesca Dell'Acqua

    La vetrata tra l'età tardo imperiale e l'altomedioevo: le fonti, l'archeologia, Tesi di Perfezionamento in Storia dell'Arte Medievale, Scuola Normale Superiore di Pisa, 2001

     

    Primo Giovanni Embriaco

    I vescovi di Albenga e gli sviluppi signorili nella Liguria occidentale (secoli XI-XIII, Tesi di dottorato di ricerca in Storia medievale, Università degli Studi di Torino, 2001

     

    Antonella Ghignoli

    Documenti e proprietà altomedievali. Fondamenti e problemi dell'esegesi storica delle fonti documentarie nello specchio della tradizione delle carte pisane dei secoli VIII-XI, Tesi di dottorato di ricerca in Storia medievale, Università degli Studi di Firenze, 2002

     

    Vito Loré

    Espansione monastica e mutamenti politici. La Trinità di Cava nei suoi rapporti con i sovrani longobardi e normanni e con l'aristocrazia territoriale. Secoli XI-XII, Tesi di dottorato di ricerca in Storia medievale, Università degli Studi di Firenze, 2002

     

    Rosaria Stracuzzi

    Messina nel '400, Tesi di dottorato di ricerca in Storia medievale, Università degli Studi di Palermo, 2001

     

    Stefania Tamburini

  1. First International Student Obtains His PhD at CAS

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ Mr. Ghulam Rasul, the first international student formally enrolled by the Graduate University of CAS (GUCAS) has received his PhD degree this summer after having passed his dissertation defense on May 21 at the CAS Institute of Atmospheric Physics (IAP).

  2. Supervising the PhD: A Guide to Success.

    Science.gov (United States)

    Delamont, Sara; Atkinson, Paul; Parry, Odette

    This handbook is a practical guide for the novice and experienced supervisor of Ph.D. students focusing on the British system. The book is organized to follow the progress of a student from starting out to a career after the viva voce examination. The chapters are: (1) "A Most Persuasive Piece of Argument"; (2) "Caught and Held by a…

  3. Peer Mentorship and Transformational Learning: PhD Student Experiences

    Science.gov (United States)

    Preston, Jane P.; Ogenchuk, Marcella J.; Nsiah, Joseph K.

    2014-01-01

    The purpose of the paper is to describe our peer mentorship experiences and explain how these experiences fostered transformational learning during our PhD graduate program in educational administration. As a literature backdrop, we discuss characteristics of traditional forms of mentorship and depict how our experiences of peer mentorship was…

  4. Richard Mazurchuk, PhD | Division of Cancer Prevention

    Science.gov (United States)

    Dr. Richard Mazurchuk received a BS in Physics and MS and PhD in Biophysics from SUNY Buffalo. His research focused on developing novel multi-modality imaging techniques, contrast (enhancing) agents and methods to assess the efficacy of experimental therapeutics. |

  5. Theo Thole as a PhD ''student''

    NARCIS (Netherlands)

    vanDuijnen, PT

    1997-01-01

    Thee Thole's Ph.D. work was the basis for the Direct Reaction Field method for incorporating a semi-classical ''solvent'' in quantum chemical calculations. The early stages of his work and later progress is reviewed and a typical example of his analytical and programming skills, so far unpublished,

  6. How Broad Liberal Arts Training Produces Phd Economists: Carleton's Story

    Science.gov (United States)

    Bourne, Jenny; Grawe, Nathan D.

    2015-01-01

    Several recent studies point to strong performance in economics PhD programs of graduates from liberal arts colleges. While every undergraduate program is unique and the likelihood of selection bias combines with small sample sizes to caution against drawing strong conclusions, the authors reflect on their experience at Carleton College to…

  7. PhD by Publication: A Student's Perspective

    Directory of Open Access Journals (Sweden)

    Peter Kanowski

    2008-01-01

    Full Text Available This article presents the first author's experiences as an Australian doctoral student undertaking a PhD by publication in the arena of the social sciences. She published nine articles in refereed journals and a peer-reviewed book chapter during the course of her PhD. We situate this experience in the context of current discussion about doctoral publication practices, in order to inform both postgraduate students and academics in general. The article discusses recent thinking about PhD by publication and identifies the factors that students should consider prior to adopting this approach, in terms of university requirements, supervisors' attitudes, the research subject matter, intellectual property, capacity and working style, and issues of co-authorship. It then outlines our perceptions of the advantages and disadvantages of undertaking a PhD by publication. We suggest that, in general, the advantages outweigh the disadvantages. We conclude by reflecting on how the first author's experiences relate to current discussions about fostering publications by doctoral students.

  8. Ph.d. report nº1

    DEFF Research Database (Denmark)

    Hernandez, Lorenzo Banos

    The following report serves as an introduction to the Ph.d subject "Control system Modeling of the Wave Star Energy's Power Take-O". The device studied belongs to the Wave Energy field, which forms part of the renewable hydro Power generation sector. In Denmark, following the succesful course...

  9. Proceedings of the ICTSS 2012 PhD Workshop - Preface

    DEFF Research Database (Denmark)

    Nielsen, Brian; Weise, Carsten

    2012-01-01

    , theoretic, and practical challenges of testing software systems, including communication protocols, services, distributed platforms, middleware, embedded systems, and security infrastructures. The aims of the ICTSS Doctoral Workshop is to provide a forum for PhD students to present preliminary results...

  10. PhD thesis: The relationship between expertise and creativity

    DEFF Research Database (Denmark)

    Boysen, Mikkel Snorre Wilms

    2015-01-01

    I Ph.d. projektet undersøges sammenhænge mellem ekspertise og kreativitet via et eksperiment, hvor eksperter og novicer laver musik ved computer. Musikken vurderes efterfølgende af en række fokusgrupper. Studiet peger overraskende på, at novicer på linje med eksperter er i stand til at skabe musi...

  11. Ph.D Afhandling: Restaurering verus instaurering og transstaurering

    DEFF Research Database (Denmark)

    Bech-Nielsen, Grith

    2012-01-01

    Ph.d. afhandlingen udforsker holdningen som arkitektfagligt instrument. Fagudøverens "holdning" til værdisætning af arkitektoniske kulturarvsobjekter og til arkitektonisk intervention heri fungerer aktuelt som et anerkendt og konstituerende beslutningsinstrument i praksisnære processer og sammenh...

  12. PhD Dissertations Tesi di dottorato

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2005-12-01

    Full Text Available Report of PhD Dissertations.Anna Airò La scrittura delle regole. Politica e istituzioni a Taranto nel Quattrocento, Tesi di dottorato di ricerca in Storia medievale, Università degli studi di Firenze, 2005 Pasquale Arfé La Clavis Physicae II (316-529 di Honorius Augustodunensis. Studio ed edizione critica, Tesi di dottorato in Storia della filosofia medievale, Università degli Studi di Napoli "L'Orientale", 2005 Alessandro Azzimonti Scrittura agiografica e strutture di potere nell'Italia centro-settentrionale (X-XII secolo, Tesi di dottorato di ricerca in Forme del sapere storico dal medioevo alla contemporaneità, Università degli Studi di Trieste, 2004 Domenico Cerami Il "Confine conteso". Uomini, istituzioni, culture a Monteveglio tra VIII-XII secolo, Tesi di dottorato di ricerca in Storia Medievale, Università degli studi di Bologna, 2005 Federica Chilà Ostaggi. Uno strumento di pacificazione e governo tra i secoli VIII e XII, Tesi di dottorato di ricerca in Istituzioni, società, religioni dal Tardo Antico alla fine del Medioevo, Università degli Studi di Torino, 2004 Enrico Faini Firenze nei secoli X-XIII: economia e società, Tesi di dottorato di ricerca in Storia medievale, Università degli studi di Firenze, 2005Alessio FioreStrutture e pratiche del potere signorile in area umbro-marchigiana (secoli XI-XIII, Tesi di dottorato ricerca in Storia, Università degli studi di Pisa, 2004Giampaolo FrancesconiTra Riforma, vescovo e clientes. Camaldoli e le società locali (secoli XI-XIII, Tesi di dottorato di ricerca in Storia medievale, Università degli studi di Firenze, 2005 [09/05] Giuseppe Gardoni "Episcopus et potestas". Vescovi e società a Mantova nella prima metà del Duecento, Tesi di dottorato di ricerca in Storia del Cristianesimo e delle Chiese (antichità, medioevo, età moderna, Università degli Studi di Padova, 2005 Nicola Mancassola La gestione delle campagne tra Langobardia e Romània in età carolingia e post

  13. Muusikauudised : Lu : k ja Jäääär koos laval. Britney Spears tegutseb. Lenny Kravitz ja Mick Jagger. Kim Wilde

    Index Scriptorium Estoniae

    2001-01-01

    Tartus Sõbra majas toimunud kontserdist. Videost "Britney: The video". Heliplaatidest: "Britney", "The Best of Pink Floyd", "Lenny", Mick Jagger "Goddess In The Doorway", "The Very Best Of Kim Wilde"

  14. Muusikauudised : Lu : k ja Jäääär koos laval. Britney Spears tegutseb. Lenny Kravitz ja Mick Jagger. Kim Wilde

    Index Scriptorium Estoniae

    2001-01-01

    Tartus Sõbra majas toimunud kontserdist. Videost "Britney: The video". Heliplaatidest: "Britney", "The Best of Pink Floyd", "Lenny", Mick Jagger "Goddess In The Doorway", "The Very Best Of Kim Wilde"

  15. The Key Indicator Method for Manual Handling Operations (KIM-MHO - evaluation of a new method for the assessment of working conditions within a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Gebhardt Hansjürgen

    2010-11-01

    Full Text Available Abstract Background Upper extremity musculoskeletal symptoms and disorders are common in the working population. The economic and social impact of such disorders is considerable. Long-time, dynamic repetitive exposure of the hand-arm system during manual handling operations (MHO alone or in combination with static and postural effort are recognised as causes of musculoskeletal symptoms and disorders. The assessment of these manual work tasks is crucial to estimate health risks of exposed employees. For these work tasks, a new method for the assessment of the working conditions was developed by the Federal Institute for Occupational Safety and Health (BAuA and released as a draft in the year 2007. The draft of the so-called Key Indicator Method for Manual Handling Operations (KIM-MHO was developed in analogy with the existing KIM for Lifting/Holding/Carrying (KIM-LHC and Pulling/Pushing (KIM-PP of loads. The KIM-MHO is designed to fill the gap existing in risk assessment of manual work processes, since the existing KIMs deal only with manual handling of loads. This research project focused on the following: - Examination of the validity of workplace assessment with the KIM-MHO comparing expert ratings with the results of the observations. - Examination of the objectivity of workplace assessment with the KIM-MHO applied by different examiners. - Examination of the criterion validity of the risk assessment provided by KIM-MHO with respect to the association between exposure and the occurrence and prevalence of health related outcomes. Methods/Design To determine the objectivity and validity of workplace assessment, the KIM-MHO is applied by occupational health and safety officers at different workplaces involving manual handling operations. To determine the criterion validity of risk assessment, a survey of employees at different workplaces takes place with standardised questionnaires and interviews about symptoms in the neck and upper extremities

  16. A STUDY ON BACTERIAL CONTAMINATION OF CELL PHONES OF HEALTH CARE WORKERS (HCW AT KIMS HOSPITAL, AMALAPURAM

    Directory of Open Access Journals (Sweden)

    Padmaja

    2014-04-01

    Full Text Available A random 100 samples of cell phones of HCWs workers and Doctors working in various wards, OPDs and laboratories, Blood Bank, Causality, ICU of KIMS Hospital were subjected to bacterial analysis by conventional methods to know about the Bacterial contamination of the cell phones from July 2011 to December 2011. The commonest organism isolated from the contaminated cell phone is MRSA - 20%, followed by MSSA - 5%, CONS - 10 %, Micrococcus - 15 %. The obvious observation is none of the doctors’ cell phones are contaminated. In the present study, the contamination rate is compared to the controlled group consisting patients, relatives attending in OPD’s and not working in health care setting.

  17. New Nordic Exceptionalism: Jeuno JE Kim and Ewa Einhorn's The United Nations of Norden and other realist utopias

    Directory of Open Access Journals (Sweden)

    Mathias Danbolt

    2016-11-01

    Full Text Available At the 2009 Nordic Culture Forum summit in Berlin that centered on the profiling and branding of the Nordic region in a globalized world, one presenter stood out from the crowd. The lobbyist Annika Sigurdardottir delivered a speech that called for the establishment of “The United Nations of Norden”: A Nordic union that would gather the nations and restore Norden's role as the “moral superpower of the world.” Sigurdardottir's presentation generated such a heated debate that the organizers had to intervene and reveal that the speech was a performance made by the artists Jeuno JE Kim and Ewa Einhorn. This article takes Kim and Einhorn's intervention as a starting point for a critical discussion of the history and politics of Nordic image-building. The article suggests that the reason Kim and Einhorn's speech passed as a serious proposal was due to its meticulous mimicking of two discursive formations that have been central to the debates on the branding of Nordicity over the last decades: on the one hand, the discourse of “Nordic exceptionalism,” that since the 1960s has been central to the promotion of a Nordic political, socio-economic, and internationalist “third way” model, and, on the other hand, the discourse on the “New Nordic,” that emerged out of the New Nordic Food-movement in the early 2000s, and which has given art and culture a privileged role in the international re-fashioning of the Nordic brand. Through an analysis of Kim and Einhorn's United Nations of Norden (UNN-performance, the article examines the historical development and ideological underpinnings of the image of Nordic unity at play in the discourses of Nordic exceptionalism and the New Nordic. By focusing on how the UNN-project puts pressure on the role of utopian imaginaries in the construction of Nordic self-images, the article describes the emergence of a discursive framework of New Nordic Exceptionalism.

  18. Report on visit from Prof. Kim Lutzen: Friday, 6 November 1998, Korolinska Institute (dept of nursing Stockholm, Sweden

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    Kim Lutzen

    1999-01-01

    Full Text Available Prof. Kim Lutzen contacted the Department of Advanced Nursing Sciences, Unisa, via the Department's Web Page. Prof. Lutzen is the Chair of the Department of Nursing, which offers undergraduate, master and doctoral programmes. This Department of Nursing is situated within the Karolinska Institute, which comprises 29 Departments of Health Sciences, including a number of Medical Departments, Dentistry, Occupational Therapy, Physiotherapy, and Nursing. Prof. Lutzen emphasised that there is no Swedish phrase similar to "nursing science", consequently this t e n seems to be somewhat unfamiliar to the Swedish nurses. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

  19. Analiza parametra translucencije staklokeramike izrađene različitim tehnološkim postupcima

    OpenAIRE

    Ledić, Karla; Majnarić, Igor; MILARDOVIĆ ORTOLAN, Slađana; Špalj, Stjepan; Štefančić, Sanja; Mehulić, Ketij

    2015-01-01

    Svrha: Analizirati parametar translucencije (TP vrijednosti) staklokeramika izrađenih različitim tehnološkim postupcima te ispitati kako na TP vrijednosti utječu korozivna sredstva. Materijali i metode: Izrađena su po tri uzorka IPS e.max keramike (Ivoclar Vivadent, Schaan, Lihtenštajn) u trima bojama (A2, C2 i B3) s trima različitim tehnologijama izrade (slojevanje – e.max Ceram Dentin; toplo-tlačna tehnika – e.max Press; strojno – e.max CAD). Uzorci su bili u obliku pločica dimenzija 10 mm ...

  20. A Density Functional Approach to Polarizable Models: A Kim-Gordon-Response Density Interaction Potential for Molecular Simulations

    Energy Technology Data Exchange (ETDEWEB)

    Tabacchi, G; Hutter, J; Mundy, C

    2005-04-07

    A combined linear response--frozen electron density model has been implemented in a molecular dynamics scheme derived from an extended Lagrangian formalism. This approach is based on a partition of the electronic charge distribution into a frozen region described by Kim-Gordon theory, and a response contribution determined by the instaneous ionic configuration of the system. The method is free from empirical pair-potentials and the parameterization protocol involves only calculations on properly chosen subsystems. They apply this method to a series of alkali halides in different physical phases and are able to reproduce experimental structural and thermodynamic properties with an accuracy comparable to Kohn-Sham density functional calculations.

  1. Undertaking Individual Transdisciplinary PhD Research for Sustainable Development: Case Studies from South Africa

    Science.gov (United States)

    van Breda, John; Musango, Josephine; Brent, Alan

    2016-01-01

    Purpose: This paper aims to improve the understanding of individual transdisciplinary PhD research in a developing country context, focusing on three individual PhD case studies in South Africa. Design/Methodology/Approach: Multiple-case method was used, and three completed transdisciplinary PhD research efforts undertaken at the Stellenbosch…

  2. Undertaking Individual Transdisciplinary PhD Research for Sustainable Development: Case Studies from South Africa

    Science.gov (United States)

    van Breda, John; Musango, Josephine; Brent, Alan

    2016-01-01

    Purpose: This paper aims to improve the understanding of individual transdisciplinary PhD research in a developing country context, focusing on three individual PhD case studies in South Africa. Design/Methodology/Approach: Multiple-case method was used, and three completed transdisciplinary PhD research efforts undertaken at the Stellenbosch…

  3. Differing estrogen activities in the organic phase of air particulate matter collected during sunny and foggy weather in a Chinese city detected by a recombinant yeast bioassay

    Science.gov (United States)

    Wang, Jingxian; Xie, Ping; Xu, Ying; Kettrup, Antonius; Schramm, Karl-Werner

    Total air suspended particles (PM 100) collected from an urban location near a traffic line in Wuhan, China, were examined for estrogen using a recombinant yeast bioassay. Wuhan, located at the central part of China, is the fourth biggest city in China with 7 million populations. Today, Wuhan has developed into the biggest city and the largest traveling center of central China, becoming one of the important bases of industry, education and research. Wuhan is right at the confluent point of Yangzi River, the third longest river in the world, and its largest distributary Hanjiang, with mountains and more than 100 lakes in downtown area. Therefore, by its unique landscape, Wuhan has formed clear four seasons with relatively long winter and summer and short spring and autumn. Foggy weather usually happen in early spring. The yeast line used in this assay stably expresses human estrogen receptor-alpha. Weak but clear estrogenic activities were detected in the organic phase of crude extracts of air particle materials (APM) in both sunny and foggy weather by 0.19-0.79 μg E2/g PM 100 which were statistically significantly elevated relative to the blank control responding from 20% to 50% of the maximum E2 response, and the estrogenic activity was much higher in foggy weather than in sunny weather. The estrogenic activities in the sub-fractions from chromatographic separation of APM sampled in foggy days were also determined. The results indicated that the responses of the fractions were obviously higher than the crude extracts. Since there is no other large pollution source nearby, the estrogenic material was most likely from vehicle emissions, house heating sources and oil fumes of house cooking. The GC/MS analysis of the PM 100 collected under foggy weather showed that there were many phenol derivatives, oxy-PAHs and resin acids which have been reported as environmental estrogens. These results of the analysis of estrogenic potency in sunny and foggy weather in a

  4. Helen Kim as New Woman and Collaborator: A Comprehensive Assessment of Korean Collaboration under Japanese Colonial Rule

    Directory of Open Access Journals (Sweden)

    AhRan Ellie Bae

    2017-02-01

    Full Text Available Although almost seventy years has passed since Korea's liberation from Japanese rule, the issue of collaboration still haunts Korea today. Attempts to resolve this issue have tended to focus attention on the traitorous actions of "collaborators" without considering the gray areas that surround their actions such as the circumstances that influenced the accused to commit their alleged traitorous acts and the intentions that drove their decisions. Helen Kim, as a "new woman" and an educator, valued the necessity of providing education for women. Yet, her efforts to realize this goal, to the contrary, forced her into actions that would later be used to construct a reputation as a Japanese collaborator. Korea's nationalist historiography has a tendency to polarize this issue by categorizing a "collaborator" as either a traitor or a patriot. However, when we take a closer look at these collaborators' lives, we discover that most collaboration happened in gray areas where it is often difficult to clearly draw a line between treason and collaboration. Helen Kim's case suggests that the issue of collaboration cannot be fully explained by nationalist historiography's framework and we must give attention to these gray areas. Through her story I hope to complicate the issue of collaboration by raising questions that address the gray areas that surround the actions of "collaborators." In doing so, I hope to challenge the nationalist historiography's propensity to oversimplify this issue and present a more nuanced understanding of it.

  5. Recovery from a Financial Meltdown: The Political Economy of Crisis Management under the Kim Dae-Jung Administration

    Directory of Open Access Journals (Sweden)

    Shalendra D. Sharma

    2002-12-01

    Full Text Available In Korea, the IMF-supported program, approved in late 1997, focused on financial sector restructuring, corporate governance, capital account liberalization, labor market reforms and trade liberalization. As in Thailand, it soon became clear that the IMF program underestimated the severity and deIn Korea, the IMF-supported program, approved in late 1997, focused on financial sector restructuring, corporate governance, capital account liberalization, labor market reforms and trade liberalization. As in Thailand, it soon became clear that the IMF program underestimated the severity and depth of the crisis. It fell upon the newly-elected government of Kim Dae-Jung to deal with both the crisis and the IMF. This paper illustrates how the Kim Dae-Jung administration deftly dealt with the grave challenges it faced. Korea's remarkable economic recovery, is in large measure, due to the government's prudent handling of the numerous economic challenges it faced. This paper examines the Korean government's management of the crisis-documenting both its achievements and the challenges ahead.

  6. The spring has arrived: traditional wild vegetables gathered by Yarsanis (Ahl-e Haqq and Sunni Muslims in Western Hawraman, SE Kurdistan (Iraq

    Directory of Open Access Journals (Sweden)

    Andrea Pieroni

    2016-11-01

    Full Text Available Kurdistan represents a crucial region in the Middle East for understanding patterns of human evolution in the use of food plants and especially wild vegetables as well as for assessing the influences of the major, surrounding bio-cultural macro-area. In this research, an ethnobotanical filed study focusing on wild vegetables traditionally gathered and consumed during the spring was conducted in a few villages of the Western Hawraman area, in South Kurdistan (Iraq, both among Sunni Muslims and Yarsanis (Ahl-e Haqq, the latter of which represent followers of a tiny, threatened, ancient monotheistic religion. Through interviews with 25 elderly informants, the folk uses of 34 botanical and mycological taxa were recorded. A few of the recorded species have never, or very rarely, been described in the ethnobotanical literature of the Middle East and for some of them (most notably Allium koelzii, Bongardia chrysogonum, Dorema aucheri, and Johrenia aromatica their sensory chemistry and nutraceutical properties are largely unknown. No differences were found between the folk taxa mentioned by Sunni Muslims and those reported by Yarsanis. The high cultural value and consumption of raw young shoots of Imperata cylindrica should be further investigated considering the history of the development of agriculture in the area, as explanations for the domestication of wild grasses have never considered the hypothesis of gastronomic appreciation of their young aerial parts. Moreover, some of the most mentioned vegetables are also considered food-medicines. A comparison with all the pre-existing food ethnobotanical literature of the Middle East shows that the most culturally salient wild vegetables recorded in the Hawraman area are shared with Arabic, Turkish, Caucasian, and especially Persian food heritages. These findings suggest that investigating the ethnobiology of Kurdistan is more than ever urgent in order to document folk plant uses at a crucial crossroad of

  7. “阳光行动”的主题内涵与实践价值%Theme Contents of "Sunny Actions" and Practical Value

    Institute of Scientific and Technical Information of China (English)

    吴敏

    2011-01-01

    The contents of "Sunny Actions" carried out by Shanxi public security could be analyzed from semantic level,academic level and practical operation.Its practical values could be defined that the "Sunny Actions" necessarily provides the effective way for achieving the "one aim,5 demands" raised by Minister Meng Jianzhu and "1+8" blueprint drafted by Public Security Department;necessarily provides reliable protection for Shanxi leapfrog development for transformation;necessarily does active contributions to making police work adapt to the new expectations and demands from the people.%山西公安系统正在开展的"阳光行动",其内涵可以从语义层面、学术层面和实践操作三个层面来进行分析。而其实践价值可以归纳为:必然能为实现孟建柱部长提出的"一个目标、五项要求"和省公安厅制定的"1+8"规划蓝图提供有效途径;必然能为山西的转型跨越发展提供可靠保障;必然能为公安工作适应时代呼唤、回应人民群众的新期望和新要求作出积极贡献。

  8. Soybean GmPHD-type transcription regulators improve stress tolerance in transgenic Arabidopsis plants.

    Directory of Open Access Journals (Sweden)

    Wei Wei

    Full Text Available BACKGROUND: Soybean [Glycine max (L. Merr.] is one of the most important crops for oil and protein resource. Improvement of stress tolerance will be beneficial for soybean seed production. PRINCIPAL FINDINGS: Six GmPHD genes encoding Alfin1-type PHD finger protein were identified and their expressions differentially responded to drought, salt, cold and ABA treatments. The six GmPHDs were nuclear proteins and showed ability to bind the cis-element "GTGGAG". The N-terminal domain of GmPHD played a major role in DNA binding. Using a protoplast assay system, we find that GmPHD1 to GmPHD5 had transcriptional suppression activity whereas GmPHD6 did not have. In yeast assay, the GmPHD6 can form homodimer and heterodimer with the other GmPHDs except GmPHD2. The N-terminal plus the variable regions but not the PHD-finger is required for the dimerization. Transgenic Arabidopsis plants overexpressing the GmPHD2 showed salt tolerance when compared with the wild type plants. This tolerance was likely achieved by diminishing the oxidative stress through regulation of downstream genes. SIGNIFICANCE: These results provide important clues for soybean stress tolerance through manipulation of PHD-type transcription regulator.

  9. Club of Bologna International Best PhD Prize 2012

    Directory of Open Access Journals (Sweden)

    Marco Fiala

    2012-06-01

    Full Text Available The Club of Bologna, in collaboration with UNACOMA, will be awarding a prize for the best PhD theses on subjects related to agricultural machinery design and development. Up to ten theses will be selected and the best five of these will have the chance of being presented during the annual Club of Bologna meeting that will be held from 9 to 10 November 2012, on occasion of the EIMA. The authors of the best three PhD theses will also receive a cash prize. The winners will be guests in Bologna of UNACOMA who will cover travelling expenses and hotel accommodation for 2 nights. They will also meet farm machinery manufacturers attending the international trade fair. The winners of the Club of Bologna Prize 2012 will be announced here. Application forms and further information can be downloaded from the Club of Bologna website (http://www.clubofbologna.org/.

  10. Iranian PhD student wins human-rights prize

    Science.gov (United States)

    Cartwright, Jon

    2013-11-01

    A physicist imprisoned in Iran while on a break from his PhD studies in the US has been awarded a human-rights prize. Omid Kokabee, who had been based at the University of Texas in Austin, has been given the Andrei Sakharov Prize from the American Physical Society (APS) for "his courage in refusing to use his physics knowledge to work on projects that he deemed harmful to humanity, in the face of extreme physical and psychological pressure".

  11. Ph.d. om interne sociale medier : Det sociale intranet

    DEFF Research Database (Denmark)

    Madsen, Vibeke Thøis

    2017-01-01

    Det sociale intranet eller interne sociale medier vækker drømme hos virksomheder, som ser en mulighed for at involvere og engagere medarbejderne. Det sociale intranet bliver opfattet som en genvej til mere innovative og effektive virksomheder. En ny ph.d. om medarbejderne som kommunikatører på...... interne sociale medier viser imidlertid, at virksomheder kæmper med at skabe en aktiv og levende kommunikation på det sociale intranet...

  12. Critical issues in PhD training for biomedical scientists.

    Science.gov (United States)

    Juliano, R L; Oxford, G S

    2001-10-01

    The rapidly changing world of modern biomedical research is raising important new issues for traditional PhD training programs and is creating concern among young PhD scientists about their futures. Specifically, the United States is producing substantially more biomedical PhDs than can be accommodated in professional positions that truly require the PhD as a credential. The "surplus" PhD population is being relegated to poorly paid, unstable, and increasingly unsatisfying jobs. In addition, many current graduate and postdoctoral training programs may not be adequately preparing young scientists for the more complex, more quantitative biological science of the future. Finally, many current graduate training programs are not attracting a sufficient portion of the most talented young people in the nation. To ameliorate these problems in the training and early career paths of basic biomedical scientists, the authors make specific recommendations, such as urging (1) that graduate trainees should be supported exclusively by competitive individual fellowships, training grants, or institutional funds and not by RO1s or similar research awards; (2) that graduate and postdoctoral stipends be increased so that they provide a reasonable living wage; and (3) that research-intensive academic institutions create a career path for biomedical PhDs other than that designed for the traditional tenure-track, grant-funded principal investigator and faculty member. They conclude that it is in the interest of faculty and institutions to make these and other drastic changes because the current system is both inherently unfair and self-destructive.

  13. The multisensor PHD filter: II. Erroneous solution via Poisson magic

    Science.gov (United States)

    Mahler, Ronald

    2009-05-01

    The theoretical foundation for the probability hypothesis density (PHD) filter is the FISST multitarget differential and integral calculus. The "core" PHD filter presumes a single sensor. Theoretically rigorous formulas for the multisensor PHD filter can be derived using the FISST calculus, but are computationally intractable. A less theoretically desirable solution-the iterated-corrector approximation-must be used instead. Recently, it has been argued that an "elementary" methodology, the "Poisson-intensity approach," renders FISST obsolete. It has further been claimed that the iterated-corrector approximation is suspect, and in its place an allegedly superior "general multisensor intensity filter" has been proposed. In this and a companion paper I demonstrate that it is these claims which are erroneous. The companion paper introduces formulas for the actual "general multisensor intensity filter." In this paper I demonstrate that (1) the "general multisensor intensity filter" fails in important special cases; (2) it will perform badly in even the easiest multitarget tracking problems; and (3) these rather serious missteps suggest that the "Poisson-intensity approach" is inherently faulty.

  14. Urinary KIM-1, NGAL and L-FABP for the diagnosis of AKI in patients with acute coronary syndrome or heart failure undergoing coronary angiography.

    Science.gov (United States)

    Torregrosa, Isidro; Montoliu, Carmina; Urios, Amparo; Andrés-Costa, María Jesús; Giménez-Garzó, Carla; Juan, Isabel; Puchades, María Jesús; Blasco, María Luisa; Carratalá, Arturo; Sanjuán, Rafael; Miguel, Alfonso

    2015-11-01

    Acute kidney injury (AKI) is a common complication after coronary angiography. Early biomarkers of this disease are needed since increase in serum creatinine levels is a late marker. To assess the usefulness of urinary kidney injury molecule-1 (uKIM-1), neutrophil gelatinase-associated lipocalin (uNGAL) and liver-type fatty acid-binding protein (uL-FABP) for early detection of AKI in these patients, comparing their performance with another group of cardiac surgery patients. Biomarkers were measured in 193 patients, 12 h after intervention. In the ROC analysis, AUC for KIM-1, NGAL and L-FABP was 0.713, 0.958 and 0.642, respectively, in the coronary angiography group, and 0.716, 0.916 and 0.743 in the cardiac surgery group. Urinary KIM-1 12 h after intervention is predictive of AKI in adult patients undergoing coronary angiography, but NGAL shows higher sensitivity and specificity. L-FABP provides inferior discrimination for AKI than KIM-1 or NGAL in contrast to its performance after cardiac surgery. This is the first study showing the predictive capacity of KIM-1 for AKI after coronary angiography. Further studies are still needed to answer relevant questions about the clinical utility of biomarkers for AKI in different clinical settings.

  15. New Nordic Exceptionalism: Jeuno JE Kim and Ewa Einhorn’s 'The United Nations of Norden' and Other Realist Utopias

    DEFF Research Database (Denmark)

    Danbolt, Mathias

    2016-01-01

    that have been central to the debates on the branding of Nordicity over the last decades: on the one hand, the discourse of “Nordic exceptionalism,” that since the 1960s has been central to the promotion of a Nordic political, socio-economic, and internationalist “third way” model, and, on the other hand......, the discourse on the “New Nordic,” that emerged out of the New Nordic Food-movement in the early 2000s, and which has given art and culture a privileged role in the international re-fashioning of the Nordic brand. Through an analysis of Kim and Einhorn’s United Nations of Norden (UNN)-performance, the article...

  16. The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts

    Directory of Open Access Journals (Sweden)

    Anna Kuchnio

    2015-08-01

    Full Text Available Several questions about the role of the oxygen sensor prolyl-hydroxylase 2 (PHD2 in cancer have not been addressed. First, the role of PHD2 in metastasis has not been studied in a spontaneous tumor model. Here, we show that global PHD2 haplodeficiency reduced metastasis without affecting tumor growth. Second, it is unknown whether PHD2 regulates cancer by affecting cancer-associated fibroblasts (CAFs. We show that PHD2 haplodeficiency reduced metastasis via two mechanisms: (1 by decreasing CAF activation, matrix production, and contraction by CAFs, an effect that surprisingly relied on PHD2 deletion in cancer cells, but not in CAFs; and (2 by improving tumor vessel normalization. Third, the effect of concomitant PHD2 inhibition in malignant and stromal cells (mimicking PHD2 inhibitor treatment is unknown. We show that global PHD2 haplodeficiency, induced not only before but also after tumor onset, impaired metastasis. These findings warrant investigation of PHD2’s therapeutic potential.

  17. Applied PhD Research in a Work-Based Environment: An Activity Theory-Based Analysis

    Science.gov (United States)

    Granata, S. N.; Dochy, F.

    2016-01-01

    Activity theory is used to compare PhD undertaken at university, that is, academic PhD, with PhD performed in collaboration with industry, that is, semi-industrial PhD. The research is divided into a literature review and a case study. Semi-industrial and academic PhD are modelled as activity systems, and differences are highlighted in terms of…

  18. Leonard F. Peltier, MD, PhD, 1920-2003.

    Science.gov (United States)

    Reckling, Frederick W; Lo Vecchio, Janolyn G; Reckling, JoAnn B

    2004-05-01

    Leonard F. Peltier, MD, PhD, was an orthopaedic surgeon, academician, administrator, laboratory investigator, historian, and mentor. His career spanned nearly six decades, beginning with graduate education at the University of Minnesota (UM) under the auspices of Owen H. Wangensteen, MD, PhD. In addition to obtaining a PhD in physiology in the UM Graduate School, he completed general and orthopaedic surgery residencies and attained board certification in each specialty. He served in the US Army Occupation Force Medical Corps in Germany just after World War II. In 1957, at 37 years old, he assumed the chairmanship of the orthopaedic training program at the University of Kansas. In 1971, he couldn't resist the opportunity to become one of the founding members of the "start-up" University of Arizona College of Medicine, accepting an appointment as chair of the new orthopaedic training program, where he remained until his retirement in 1990. He took clinical problems to the laboratory, and made important scientific contributions, particularly in the area of fat embolism and in using calcium sulfate (plaster of Paris) to fill bone defects. He served on governing boards of national professional organizations and presided over the American Association for the Surgery of Trauma from 1980-1981. Throughout his career, he was fascinated by, and published extensively in, the history of medicine arena. Known fondly as "the professor" to many of his residents and colleagues, he had a pragmatic, honest, upbeat, and often humorous approach to life's challenges, valuing personal integrity above other virtues. He explored various eclectic interests far beyond his professional contributions while maintaining his family as a central priority. With his exemplary productivity and interests in the surgical and laboratory sciences, history of medicine, appreciation of fine arts, and perceptive and effective interactions with family, friends, patients, and colleagues, the memory of Leonard

  19. MS PHD'S Professional Development Program: A Scientific Renaissance in Cyberspace

    Science.gov (United States)

    Powell, J. M.; Williamson, V. A.; Griess, C. A.; Pyrtle, A. J.

    2004-12-01

    This study is a component of a four-year investigation of MS PHD'S Professional Development Program's virtual community through the lenses of underrepresented minority students in Earth system science and engineering fields. In this presentation, the development, assessment and projected utilization of the ongoing study will be discussed. The overall goal of this study is to examine the effectiveness of virtual team building methods and understand how the development of a communal cyberinfrastructure acts as an integral part of the emergence of a Scientific Renaissance. The exemplar, Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science (MS PHD'S), provides professional development experiences to facilitate the advancement of students of color achieving outstanding Earth system careers. Undergraduate and graduate students are supported through access to scientific conferences, mentorship and virtual community building. Framed by critical theory, this ethnographic exploration uses a mixed methods research design to record, observe, and analyze both the processes and products of the website, listserv and synchronous web-based dialogue. First, key findings of the formative evaluation and annual reports of the successfully implemented 2003 MS PHD'S Pilot Project are presented. These findings inform future evaluations of the use of technological resources and illustrate how this public space provides peer support and enriched research opportunities. Quantitative methods such as statistical analysis, academic and professional tracking and evaluative tools for scientific content and competency are complimented by qualitative methods that include observations, heuristic case studies and focus group interviews. The findings of this ongoing investigation will provide insight on how national organizations, higher education practitioners, community-based support systems and underrepresented minorities in the sciences promote diversity by developing

  20. Expanded radio art as PhD practice

    OpenAIRE

    Hall, M.

    2015-01-01

    Radio After Radio: Redefining Radio Art in the Light of New Media Technology through Expanded Practice is the title of my PhD practice based research. This paper focuses on the extended boundaries of radio art, considering how radio art might be defined in relation to sound art, music, and media art. Mapping the shifting parameters of radio art in the digital era has prompted a consideration of how radio can be seen to be moving from being a predominantly shared "live" event to one consumed "...

  1. Hrvoje Tomić, PhD in Technical Sciences

    Directory of Open Access Journals (Sweden)

    Siniša Mastelić Ivić

    2010-12-01

    Full Text Available Hrvoje Tomić defended his PhD thesis Geospatial Data Analysis for the Purpose of Real Estate Valuation in Urban Areas at the Faculty of Geodesy, University of Zagreb, on November 15, 2010. His mentor was Prof. Dr. Siniša Mastelić Ivić, and the other two members of the Grading and Defence Committee were Assist. Prof. Dr. Vlado Cetl and Prof. Dr. Goran Poljanec from the Faculty of Civil Engineering, University of Zagreb.

  2. Exploring PHD fingers and H3K4me0 interactions with molecular dynamics simulations and binding free energy calculations: AIRE-PHD1, a comparative study.

    Directory of Open Access Journals (Sweden)

    Dimitrios Spiliotopoulos

    Full Text Available PHD fingers represent one of the largest families of epigenetic readers capable of decoding post-translationally modified or unmodified histone H3 tails. Because of their direct involvement in human pathologies they are increasingly considered as a potential therapeutic target. Several PHD/histone-peptide structures have been determined, however relatively little information is available on their dynamics. Studies aiming to characterize the dynamic and energetic determinants driving histone peptide recognition by epigenetic readers would strongly benefit from computational studies. Herein we focus on the dynamic and energetic characterization of the PHD finger subclass specialized in the recognition of histone H3 peptides unmodified in position K4 (H3K4me0. As a case study we focused on the first PHD finger of autoimmune regulator protein (AIRE-PHD1 in complex with H3K4me0. PCA analysis of the covariance matrix of free AIRE-PHD1 highlights the presence of a "flapping" movement, which is blocked in an open conformation upon binding to H3K4me0. Moreover, binding free energy calculations obtained through Molecular Mechanics/Poisson-Boltzmann Surface Area (MM/PBSA methodology are in good qualitative agreement with experiments and allow dissection of the energetic terms associated with native and alanine mutants of AIRE-PHD1/H3K4me0 complexes. MM/PBSA calculations have also been applied to the energetic analysis of other PHD fingers recognizing H3K4me0. In this case we observe excellent correlation between computed and experimental binding free energies. Overall calculations show that H3K4me0 recognition by PHD fingers relies on compensation of the electrostatic and polar solvation energy terms and is stabilized by non-polar interactions.

  3. AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome.

    Science.gov (United States)

    Gaetani, Massimiliano; Matafora, Vittoria; Saare, Mario; Spiliotopoulos, Dimitrios; Mollica, Luca; Quilici, Giacomo; Chignola, Francesca; Mannella, Valeria; Zucchelli, Chiara; Peterson, Pärt; Bachi, Angela; Musco, Giovanna

    2012-12-01

    Mutations in autoimmune regulator (AIRE) gene cause autoimmune polyendocrinopathy candidiasis ectodermal dystrophy. AIRE is expressed in thymic medullary epithelial cells, where it promotes the expression of peripheral-tissue antigens to mediate deletional tolerance, thereby preventing self-reactivity. AIRE contains two plant homeodomains (PHDs) which are sites of pathological mutations. AIRE-PHD fingers are important for AIRE transcriptional activity and presumably play a crucial role in the formation of multimeric protein complexes at chromatin level which ultimately control immunological tolerance. As a step forward the understanding of AIRE-PHD fingers in normal and pathological conditions, we investigated their structure and used a proteomic SILAC approach to assess the impact of patient mutations targeting AIRE-PHD fingers. Importantly, both AIRE-PHD fingers are structurally independent and mutually non-interacting domains. In contrast to D297A and V301M on AIRE-PHD1, the C446G mutation on AIRE-PHD2 destroys the structural fold, thus causing aberrant AIRE localization and reduction of AIRE target genes activation. Moreover, mutations targeting AIRE-PHD1 affect the formation of a multimeric protein complex at chromatin level. Overall our results reveal the importance of AIRE-PHD domains in the interaction with chromatin-associated nuclear partners and gene regulation confirming the role of PHD fingers as versatile protein interaction hubs for multiple binding events.

  4. Understanding internal backgrounds in NaI(Tl) crystals toward a 200 kg array for the KIMS-NaI experiment

    Energy Technology Data Exchange (ETDEWEB)

    Adhikari, P.; Adhikari, G.; Oh, S.Y. [Sejong University, Department of Physics, Seoul (Korea, Republic of); Choi, S.; Joo, H.W.; Kim, K.W.; Kim, S.K. [Seoul National University, Department of Physics and Astronomy, Seoul (Korea, Republic of); Ha, C.; Jeon, E.J.; Kang, W.G.; Kim, H.O.; Kim, N.Y.; Lee, H.S.; Lee, J.H.; Lee, M.H.; Leonard, D.S.; Li, J.; Olsen, S.L.; Park, H.K.; Park, K.S.; So, J.H.; Yoon, Y.S. [Institute for Basic Science, Center for Underground Physics, Daejeon (Korea, Republic of); Hahn, I.S. [Ewha Womans University, Department of Science Education, Seoul (Korea, Republic of); Kim, H.J. [Kyungpook National University, Department of Physics, Daegu (Korea, Republic of); Kim, Y.D. [Sejong University, Department of Physics, Seoul (Korea, Republic of); Institute for Basic Science, Center for Underground Physics, Daejeon (Korea, Republic of); Kim, Y.H. [Institute for Basic Science, Center for Underground Physics, Daejeon (Korea, Republic of); Korea Research Institute of Standards and Science, Daejeon (Korea, Republic of); Park, H.S. [Korea Research Institute of Standards and Science, Daejeon (Korea, Republic of)

    2016-04-15

    The Korea Invisible Mass Search (KIMS) collaboration has developed low-background NaI(Tl) crystals that are suitable for the direct detection of WIMP dark matter. Building on experience accumulated during the KIMS-CsI programs, the KIMS-NaI experiment will consist of a 200 kg NaI(Tl) crystal array surrounded by layers of shielding structures and will be operated at the Yangyang underground laboratory. The goal is to provide an unambiguous test of the DAMA/LIBRA annual modulation signature. Measurements of six prototype crystals show progress in the reduction of internal contamination from radioisotopes. Based on our understanding of these measurements, we expect to achieve a background level in the final detector configuration that is less than 1 count/day/keV/kg for recoil energies around 2 keV. The annual modulation sensitivity for the KIMS-NaI experiment shows that an unambiguous 7σ test of the DAMA/LIBRA signature would be possible with a 600 kg year exposure with this system. (orig.)

  5. Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Kidney Injury Molecule 1 (KIM1) in patients with diabetic nephropathy: a cross-sectional study and the effects of lisinopril

    DEFF Research Database (Denmark)

    Nielsen, S E; Schjoedt, K J; Astrup, A S

    2010-01-01

    Our aim was to evaluate the markers of tubulointerstitial damage, neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule1 (KIM1) in Type 1 diabetic patients with different levels of albuminuria and in control subjects. In addition, the effect of renoprotective treatment...... on urinary NGAL was evaluated in diabetic nephropathy....

  6. Social Status Construction of the Kim Families ’ in Xiuning County%休宁金氏宗族社会地位构建

    Institute of Scientific and Technical Information of China (English)

    朱玉荣

    2014-01-01

    徽州是典型的宗族社会,等级门第观念较严格,社会地位高低是宗族能否立足的重要凭证,因此,提高宗族的社会地位是宗族赋予族众的使命。休宁金氏宗族传承千年,世代以忠孝显名。通过对《休宁金氏族谱》进行研究可知,金氏宗族构建社会地位的方式主要有进行宗族管理、获得社会认同和官府认同等三方面。%Huizhou was a typical clan society .obsession of hierarchy here was stricter .So ,it was important to improve the clan’s social status ,which was the families’ mission .The Kim families in Xiuning County had been inherited for more than one thousand years .They were famous for their loyalty and filial piety .To build social status ,the Kim families made unre-mitting efforts .According to The Kim Families’ documents ,we can know that the Kim families built their social status by clan managing ,obtaining social identity and official recognition .

  7. Reduction of proteinuria in adriamycin-induced nephropathy is associated with reduction of renal kidney injury molecule (Kim-1) over time

    NARCIS (Netherlands)

    Kramer, Andrea B.; van Timmeren, Mirjan M.; Schuurs, Theo A.; Vaidya, Vishal S.; Bonventre, Joseph V.; van Goor, Harry; Navis, Gerjan

    2009-01-01

    Kramer AB, van Timmeren MM, Schuurs TA, Vaidya VS, Bonventre JV, van Goor H, Navis G. Reduction of proteinuria in adriamycin-induced nephropathy is associated with reduction of renal kidney injury molecule (Kim-1) over time. Am J Physiol Renal Physiol 296: F1136-F1145, 2009. First published February

  8. Understanding internal backgrounds of NaI(Tl) crystals toward a 200~kg array for the KIMS-NaI experiment

    CERN Document Server

    Adhikari, P; Choi, S; Ha, C; Hahn, I S; Jeon, E J; Joo, H W; Kang, W G; Kim, H J; Kim, H O; Kim, K W; Kim, N Y; Kim, S K; Kim, Y D; Kim, Y H; Lee, H S; Lee, J H; Lee, M H; Leonard, D S; Li, J; Oh, S Y; Olsen, S L; Park, H K; Park, H S; Park, K S; So, J H; Yoon, Y S

    2015-01-01

    The Korea Invisible Mass Search (KIMS) collaboration has developed low-background NaI(Tl) crystals that are suitable for the direct detection of WIMP dark matter. With experience built on the KIMS-CsI programs, the KIMS-NaI experiment will consist of a 200~kg NaI(Tl) crystal array surrounded by layers of shielding structures and will be operated at the Yangyang underground laboratory. The goal is to provide an unambiguous test of the DAMA/LIBRA's annual modulation signature. Measurements of six prototype crystals show progress in the reduction of internal contaminations of radioisotopes. Based on our understanding of these measurements, we expect to achieve a background level in the final detector configuration that is less than 1~count/day/keV/kg for recoil energies around 2~keV. The annual modulation sensitivity for the KIMS-NaI experiment shows that an unambiguous 7$\\sigma$ test of the DAMA/LIBRA signature would be possible with a 600~kg$\\cdot$year exposure with this system.

  9. VALIDATION OF COOKING TIMES AND TEMPERATURES FOR THERMAL INACTIVATION OF YERSINIA PESTIS STRAINS KIM5 AND CDC-A1112 IN GROUND BEEF

    Science.gov (United States)

    The thermal stability of Yersinia pestis inoculated into retail ground beef (25 per cent fat) and heated in a temperature-controlled water bath or cooked on commercial grills was evaluated. Irradiated ground beef (3-g portions) was inoculated with ca. 6.7 log10 CFU/g of Y. pestis strain KIM5 and hea...

  10. The Exploration on the Positive Psychological Assessment Indicator of "Sunny Physical Culture" on Campus%高校“阳光体育运动”的积极心理评价指标探索

    Institute of Scientific and Technical Information of China (English)

    严军锋

    2012-01-01

    文章根据心理学相关理论与研究,结合高校"阳光体育运动"的评价现状认为,现阶段的有关高校"阳光体育运动"的评价缺乏对大学生积极心理层面的指标研究。文章详细介绍了流畅状态与锻炼承诺的理论及两者在大众锻炼领域的应用现状,结合高校"阳光体育运动"认为流畅状态与锻炼承诺可以作为高校"阳光体育运动"的心理评价指标,两者可以反映高校"阳光体育运动"心理层面的价值。%Based on the related theory and the studies,the paper indicates that the recent assessment of "Sunny Physical Culture" is in great lack of the study into the psychological indicator in the dimension of the positive mind.The paper fully introduces the notion of smooth statement and training commitment as well as the application of the two in the public physical training,combined with the perspective that "Sunny Physical Culture" argues that smooth statement and training commitment could work as the indicators of psychological assessment of "Sunny Physical Culture" on campus.Both of the indicators can reflect the true value of "Sunny Physical Culture" in the psychological dimension.

  11. I-determinants for a successful PhD or postdoctoral outcome.

    Science.gov (United States)

    Sørensen, Henrik Toft

    2016-01-01

    Many resources are invested in research training, but very little literature exists on predictors for a successful PhD and postdoctoral training outcome. A PhD program has two overall objectives: to extend knowledge about a hopefully important health topic and to provide extensive training to improve the PhD student's skills through learning research methods and collaboration. A substantial number of PhD students may run into some kind of problem in the course of their PhD program. In this article, some determinants all starting with an "I" and indicative of a good PhD outcome are reported. The successful PhD student can be described as having an Interest in the PhD program, an Incentive for the program, and an Idea of what he or she wants to investigate, showing Initiative, and having high personal Integrity and good Interpersonal relationships. When these so-called I-determinants are present, the likelihood of success in a PhD program is high. More evidence is available for selection of candidates for postdoctoral appointments since it is known that the postdoctoral candidate has completed a PhD program, published papers in peer-reviewed journals, and received awarded grants. However, other characteristics determine a successful transition of the postdoctoral candidate into a research leader. These determinants are Identity, Independence and Image, Implementation ability in terms of being able to implement decisions and projects, working with Innovative and Important topics, having In-depth knowledge of the research topic, being Interactive and Integrated with the scientific community, and Internationally oriented. In conclusion, regardless of the framework of research, the personal characteristics of a researcher play a very important role in the quality of research. Application of some of the principles mentioned in this article might allow decision to reach a more evidence-based way to recruit PhD students and postdoctorals.

  12. VizieR Online Data Catalog: Spitzer/IRS survey of Class II objects in Orion A. I. (Kim+, 2016)

    Science.gov (United States)

    Kim, K. H.; Watson, D. M.; Manoj, P.; Forrest, W. J.; Furlan, E.; Najita, J.; Sargent, B.; Hernandez, J.; Calvet, N.; Adame, L.; Espaillat, C.; Megeath, S. T.; Muzerolle, J.; McClure, M. K.

    2016-10-01

    We present 319 Class II disks observed with Spitzer/IRS in the Orion A star-forming region. We described the Spitzer/IRS and IRTF/SpeX observations and data reduction process in Kim+ (2013, J/ApJ/769/149). The Orion A objects in this paper were selected based on the identification of young stars with disks by IRAC/Two Micron All Sky Survey (2MASS) color-color diagrams (Megeath+ 2012, J/AJ/144/192). We observed them using Spitzer/IRS during campaigns 36, 39, 40, and 44 between 2006 November and 2007 October. To this group we added 16 additional objects (5 in the ONC; 11 in L1641) that were reclassified as Class II from Class 0/I sources observed in the Orion A protostar survey by C. Poteet et al. (2016, in preparation); 14 of these 16 were observed during campaigns 39 and 40, but 2 sources were observed in campaign 56 (see table 1). Of our IRS targets observed in both SL and LL modules in Orion A with Spitzer/IRS, we observed 120 at near-IR (0.8-2.4um) wavelengths with the medium-resolution spectrograph SpeX, on the NASA IRTF on Mauna Kea during the 2010A, 2011A, and 2011B semesters (see table 3). (9 data files).

  13. Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science (MS PHD'S) Beyond the PhD Professional Development Program: A Pilot Project

    Science.gov (United States)

    Johnson, A.; Jearld, A.; Williamson Whitney, V.; Huggans, M.; Ricciardi, L.; Thomas, S. H.; Jansma, P. E.

    2012-12-01

    In 2011 the Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science (MS PHD'S)® initiative launched its newest activity entitled the MS PHD'S "Beyond the PhD (B-PhD) Professional Development Program." This exciting new program was designed to facilitate the development of a new community of underrepresented minority (URM) doctoral candidates and recent doctorate degree recipients in Earth system science (ESS)-related fields. The MS PHD'S B-PhD provides customized support and advocacy for MS PHD'S B-PhD participants in order to facilitate smoother and informed transitions from graduate school, to postdoctoral and tenure-track positions, as well as other "first" jobs in government, industry, and non-profit organizations. In November 2011 the first cohort of MS PHD'S B-PhD participants engaged in intensive sessions on the following topics: "Toolkits for Success for Academia, Business/Industry, Federal Government and Non-Profits", "Defining Short, Mid and Long Term Career Goals", "Accessing and Refining Skill Sets and Other Door Openers", "International Preparation and Opportunities", "Paying it Forward/Lifting as You Climb", and "Customized Strategies for Next Steps". This pilot event, which was hosted by the University of Texas at Arlington's (UTA) College of Science, also provided opportunities for participants to serve as guest lecturers in the UTA's Colleges of Science and Engineering and included one-on-one discussions with MS PHD'S B-PhD mentors and guest speakers who are well established within their individual ESS fields. Insights regarding opportunities, challenges and obstacles commonly faced by URMs within the ESS fields, as well as strategies for success were shared by MS PHD'S B-PhD mentors and guest speakers. Survey results indicate that MS PHD'S B-PhD participants appreciated not only the material covered during this pilot activity, but also appreciated the opportunity to become part of a community of young URM ESS

  14. Research(er) at Home: Auto/Ethnography of (My) PhD

    Science.gov (United States)

    Benová, Kamila

    2014-01-01

    This article deals with the PhD phase of tertiary higher education (in Slovakia), which is here considered as the specific phase of the academic career. It tries to answer the question: what is the PhD, in the context of research, theoretically and methodologically approached as a critical ethnography of higher education. It is focused on the…

  15. Enhancing the Industrial PhD Programme as a Policy Tool for University-Industry Cooperation

    Science.gov (United States)

    Roolaht, Tõnu

    2015-01-01

    The changing role of universities in society includes the increasing expectation that academic institutions should engage in collaboration with companies. Industrial PhD programmes are educational tools for building bridges between the academic sector and industry. In these programmes, the PhD student studies and carries out research while being…

  16. Enhancing the Industrial PhD Programme as a Policy Tool for University-Industry Cooperation

    Science.gov (United States)

    Roolaht, Tõnu

    2015-01-01

    The changing role of universities in society includes the increasing expectation that academic institutions should engage in collaboration with companies. Industrial PhD programmes are educational tools for building bridges between the academic sector and industry. In these programmes, the PhD student studies and carries out research while being…

  17. Intercultural PhD Supervision: Exploring the Hidden Curriculum in a Social Science Faculty Doctoral Programme

    Science.gov (United States)

    Kidman, Joanna; Manathunga, Catherine; Cornforth, Sue

    2017-01-01

    International knowledge markets rely heavily on a ready supply of highly mobile doctoral students, many of whom are from the global South, to bring in revenue. The supervision of these PhD students, however, can reproduce neo-colonial knowledge relations, often in subtle ways. In settler nations, international PhD students may find that they are…

  18. Creating Entrepreneurial Networks: Academic Entrepreneurship, Mobility and Collaboration during PhD Education

    Science.gov (United States)

    Bienkowska, Dzamila; Klofsten, Magnus

    2012-01-01

    Network-building activities of PhD students are an important area of study in furthering our understanding of academic entrepreneurship. This paper focuses on PhD students' participation in network-building activities defined as mobility and collaboration, as well as own interest in and perceived grade of support for commercialisation from various…

  19. Searching for "A Third Space": A Creative Pathway towards International PhD Students' Academic Acculturation

    Science.gov (United States)

    Elliot, Dely Lazarte; Baumfield, Vivienne; Reid, Kate

    2016-01-01

    Undertaking a PhD is a challenging endeavour. Pursuing a doctoral education in a "foreign" context tends to increase the demands of this intellectual venture. The nature of research-based PhD programmes, often characterised by a lack of formal curricula where academic supervision lasts several years, may add another layer of complexity.…

  20. Self-efficacy is related to PhD completion time: possible tool for interventions

    NARCIS (Netherlands)

    Bouma, Esther

    2015-01-01

    Every two years the University of Groningen evaluates PhD' satisfaction concerning education and working environment. The goal is to create an environment in which PhD's can develop the necessary research skills for their projects as well as finish these projects in time. At Dutch universities most

  1. The Undergraduate Origins of PhD Economists: The Berkeley Experience

    Science.gov (United States)

    Olney, Martha L.

    2015-01-01

    The University of California, Berkeley sends more undergraduate students to economics PhD programs than any other public university. While this fact is surely a function of its size, there may be lessons from the Berkeley experience that others could adopt. To investigate why Berkeley generates so many economics PhD students, the author convened…

  2. Problems Should Be Paid Attention to Develop Winter Sunny Sports in Universities%高校冬季开展阳光体育运动应注意的问题

    Institute of Scientific and Technical Information of China (English)

    张娉婷

    2013-01-01

    开展“阳光体育运动”对增进学生体质与身心健康具有重要的作用,是新时期加强高校体育教学工作的战略措施。冬季体育的教育观念和冬季体育教学的目标对高校冬季阳光体育运动开展起主导作用,高校冬季开展阳光体育运动应注意将阳光体育运动目标与高校体育教育目标有机的结合,把握好校园体育基础设施条件硬件与体育文化软件的建设,处理好阳光体育运动与学校体育的关系,需要建立长效机制,制定长远的战略发展规划,从法规、制度和管理等不同的层面为其提供保障。%Developing sunny sports plays an important role in improving the physical and mental health of students , is a measure to strengthen physical education in universities during new period .The educational i-dea of winter sports and the goal of winter sports teaching have a leading function to develop winter sunny sports in universities .Developing winter sunny sports in universities should pay attention to combine the goal of sunny sports with the goal of physical education , grasp the construction of campus's sports facilities of hardware and physical culture of software , deal well with the relationship between sunny sports and sports in universities , and need to establish a long-effect mechanism , make a long-term strategic developing plan , and provide protection from the laws , regulations and management and other different aspects .

  3. The Virtual Observatory Powered PhD Thesis

    CERN Document Server

    Zolotukhin, Ivan

    2010-01-01

    The Virtual Observatory has reached sufficient maturity for its routine scientific exploitation by astronomers. To prove this statement, here I present a brief description of the complete VO-powered PhD thesis entitled "Galactic and extragalactic research with modern surveys and the Virtual Observatory" comprising 4 science cases covering various aspects of astrophysical research. These comprize: (1) homogeneous search and measurement of main physical parameters of Galactic open star clusters in huge multi-band photometric surveys; (2) study of optical-to-NIR galaxy colors using a large homogeneous dataset including spectroscopy and photometry from SDSS and UKIDSS; (3) study of faint low-mass X-ray binary population in modern observational archives; (4) search for optical counterparts of unidentified X-ray objects with large positional uncertainties in the Galactic Plane. All these projects make heavy use of the VO technologies and tools and would not be achievable without them. So refereed papers published i...

  4. PHD2: from hypoxia regulation to disease progression.

    Science.gov (United States)

    Meneses, Ana M; Wielockx, Ben

    2016-01-01

    Oxygen represents one of the major molecules required for the development and maintenance of life. An adequate response to hypoxia is therefore required for the functioning of the majority of living organisms and relies on the activation of the hypoxia-inducible factor (HIF) pathway. HIF prolyl hydroxylase domain-2 (PHD2) has long been recognized as the major regulator of this response, controlling a myriad of outcomes that range from cell death to proliferation. However, this enzyme has been associated with more pathways, making the role of this protein remarkably complex under distinct pathologies. While a protective role seems to exist in physiological conditions such as erythropoiesis; the picture is more complex during pathologies such as cancer. Since the regulation of this enzyme and its closest family members is currently considered as a possible therapy for various diseases, understanding the different particular roles of this protein is essential.

  5. On M. Mueter's Ph.D. Thesis on Cheeger deformations

    CERN Document Server

    Ziller, Wolfgang

    2009-01-01

    These are notes of a talk I gave in a seminar at the University of Pennsylvania summarizing results in the Ph.D. thesis of Michael Mueter obtained under the direction of Wolfgang Meyer at the University of Muenster. His thesis on "Kruemmungserhoehende Deformationen mittels Gruppenaktionen" examines in detail curvature properties of so called Cheeger deformations. Such deformations have been a crucial ingredient in non-negative and positive curvature constructions. His thesis contains a wealth of interesting properties of such deformations, but since it was never published, is only known to a few experts. I have no intention to publish these notes, but post them as a service to the public. A scanned version of his thesis (written in German) is available on my homepage.

  6. PhD Thesis: Functional Textiles in Hospital Interiors

    DEFF Research Database (Denmark)

    Mogensen, Jeppe Emil

    consists of a collection of 5 peer-reviewed papers, and an extended summary. The project is overall related to the construction of new Danish hospitals, where the design concept healing architecture is intro- duced in a national context, representing the vision of a promoted healing process of hospitalised...... of plastic, vinyl and steel. These materials also dominate the new hospitals, designed and constructed these years, and despite the increased focus on the design concept healing architecture, the rational requirements of ef cient cleaning and maintenance still seems to direct the interior design of hospital...... of this PhD project has been to explore the possibilities and design qualities of using these materials in hospital inte- rior design. Relating to both technical and aesthetic aspects of using functional textiles in hospitals, the project seeks to integrate these aspects, departing from the overall research...

  7. Researcher Profile: An Interview with Jodi Letkiewicz, Ph.D.

    Directory of Open Access Journals (Sweden)

    Jodi Letkiewicz

    2014-12-01

    Full Text Available Jodi Letkiewicz, Ph.D., is an assistant professor of finance at York University in Toronto, Ontario. She teaches in the Certified Financial Planner® Core Curriculum program preparing undergraduate students for the Canadian CFP® certification and conducts research in several areas of personal finance and consumer decision-making, including behavioral aspects influencing the decision to seek financial help, how personality traits affect financial decision-making, and the financial state of young adults, including the impact student loans have on overall well-being and financial milestones early in their adult life. Dr. Letkiewicz’s goal is to increase financial well-being in the general public, which she hopes to accomplish through teaching, research, and community outreach.

  8. Attitude of PhD Students Towards Academic Dishonesty

    Directory of Open Access Journals (Sweden)

    Vilija Grincevičienė

    2011-04-01

    Full Text Available The article describes the problem of academic dishonesty. Looking over the results of research done in foreign countries (the USA, Romania, Poland, it is possible to assert that the ethics of a scientist is a topical problem nowadays not only in Lithuania but also all over the world. The results of pilot research show that although in all curricula, textbooks and other sources it is declared that each researcher or a team must keep to certain ethics rules, not everything goes well. Respondents were first year PhD students of Vilnius Gediminas Technical University (N=51. Taking into account the results, more attention should be paid to the analysis and correction of the situation.

  9. Analysis list: ph-d [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ph-d Cell line,Embryo + dm3 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/target/p...h-d.1.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/target/ph-d.5.tsv http://dbarchive.biosciencedbc.jp.../kyushu-u/dm3/target/ph-d.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/colo/ph-d.Cell_line.tsv,http://dbarchive.bioscience...dbc.jp/kyushu-u/dm3/colo/ph-d.Embryo.tsv http://dbarchive.bioscience...dbc.jp/kyushu-u/dm3/colo/Cell_line.gml,http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/colo/Embryo.gml ...

  10. The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A

    Directory of Open Access Journals (Sweden)

    Inmaculada Segura

    2016-03-01

    Full Text Available Neuronal function is highly sensitive to changes in oxygen levels, but how hypoxia affects dendritic spine formation and synaptogenesis is unknown. Here we report that hypoxia, chemical inhibition of the oxygen-sensing prolyl hydroxylase domain proteins (PHDs, and silencing of Phd2 induce immature filopodium-like dendritic protrusions, promote spine regression, reduce synaptic density, and decrease the frequency of spontaneous action potentials independently of HIF signaling. We identified the actin cross-linker filamin A (FLNA as a target of PHD2 mediating these effects. In normoxia, PHD2 hydroxylates the proline residues P2309 and P2316 in FLNA, leading to von Hippel-Lindau (VHL-mediated ubiquitination and proteasomal degradation. In hypoxia, PHD2 inactivation rapidly upregulates FLNA protein levels because of blockage of its proteasomal degradation. FLNA upregulation induces more immature spines, whereas Flna silencing rescues the immature spine phenotype induced by PHD2 inhibition.

  11. Multi-Target Detection from Full-Waveform Airborne Laser Scanner Using Phd Filter

    Science.gov (United States)

    Fuse, T.; Hiramatsu, D.; Nakanishi, W.

    2016-06-01

    We propose a new technique to detect multiple targets from full-waveform airborne laser scanner. We introduce probability hypothesis density (PHD) filter, a type of Bayesian filtering, by which we can estimate the number of targets and their positions simultaneously. PHD filter overcomes some limitations of conventional Gaussian decomposition method; PHD filter doesn't require a priori knowledge on the number of targets, assumption of parametric form of the intensity distribution. In addition, it can take a similarity between successive irradiations into account by modelling relative positions of the same targets spatially. Firstly we explain PHD filter and particle filter implementation to it. Secondly we formulate the multi-target detection problem on PHD filter by modelling components and parameters within it. At last we conducted the experiment on real data of forest and vegetation, and confirmed its ability and accuracy.

  12. Solar Spectral and Module Temperature Influence on the Outdoor Performance of Thin Film PV Modules Deployed on a Sunny Inland Site

    Directory of Open Access Journals (Sweden)

    G. Nofuentes

    2013-01-01

    Full Text Available This work aims at analysing the influence of both module temperature and solar spectrum distribution on the outdoor performance of the following thin film technologies: hydrogenated amorphous silicon (a-Si:H, cadmium telluride (CdTe, copper indium gallium selenide sulfide (CIGS, and hydrogenated amorphous silicon/hydrogenated microcrystalline silicon hetero-junction (a-Si:H/μc-Si:H. A 12-month experimental campaign carried out in a sunny inland site in which a module of each one of these technologies was tested and measured outdoors has provided the necessary empirical data. Results show that module temperature exerts a limited influence on the performance of the tested a-Si:H, CdTe, and a-Si:H/μc-Si:H modules. In contrast, the outdoor behaviour of the CIGS module is the most affected by its temperature. Blue-rich spectra enhance the outdoor behaviour of the a-Si:H and a-Si:H/μc-Si:H modules while it is the other way round for the CIGS module. However, the CdTe specimen shows little sensitivity to the solar spectrum distribution. Anyway, spectral effects are scarcely relevant on an annual basis, ranging from gains for the CIGS module (1.5% to losses for the a-Si:H module (1.0%. However, the seasonal impact of the spectrum shape is more noticeable in these two materials; indeed, spectral issues may cause performance gains or losses of up to some 4% when winter and summer periods are considered.

  13. Prolyl-4-hydroxylase 3 (PHD3 expression is downregulated during epithelial-to-mesenchymal transition.

    Directory of Open Access Journals (Sweden)

    Trenton L Place

    Full Text Available Prolyl-4-hydroxylation by the intracellular prolyl-4-hydroxylase enzymes (PHD1-3 serves as a master regulator of environmental oxygen sensing. The activity of these enzymes is tightly tied to tumorigenesis, as they regulate cell metabolism and angiogenesis through their control of hypoxia-inducible factor (HIF stability. PHD3 specifically, is gaining attention for its broad function and rapidly accumulating array of non-HIF target proteins. Data from several recent studies suggest a role for PHD3 in the regulation of cell morphology and cell migration. In this study, we aimed to investigate this role by closely examining the relationship between PHD3 expression and epithelial-to-mesenchymal transition (EMT; a transcriptional program that plays a major role in controlling cell morphology and migratory capacity. Using human pancreatic ductal adenocarcinoma (PDA cell lines and Madin-Darby Canine Kidney (MDCK cells, we examined the correlation between several markers of EMT and PHD3 expression. We demonstrated that loss of PHD3 expression in PDA cell lines is highly correlated with a mesenchymal-like morphology and an increase in cell migratory capacity. We also found that induction of EMT in MDCK cells resulted in the specific downregulation of PHD3, whereas the expression of the other HIF-PHD enzymes was not affected. The results of this study clearly support a model by which the basal expression and hypoxic induction of PHD3 is suppressed by the EMT transcriptional program. This may be a novel mechanism by which migratory or metastasizing cells alter signaling through specific pathways that are sensitive to regulation by O2. The identification of downstream pathways that are affected by the suppression of PHD3 expression during EMT may provide important insight into the crosstalk between O2 and the migratory and metastatic potential of tumor cells.

  14. MATLAB simulation software used for the PhD thesis "Acquisition of Multi-Band Signals via Compressed Sensing

    DEFF Research Database (Denmark)

    2014-01-01

    MATLAB simulation software used for the PhD thesis "Acquisition of Multi-Band Signals via Compressed Sensing......MATLAB simulation software used for the PhD thesis "Acquisition of Multi-Band Signals via Compressed Sensing...

  15. Kim Scott’s Fiction within Western Australian Life-Writing: Voicing the Violence of Removal and Displacement

    Directory of Open Access Journals (Sweden)

    Cornelis Martin Renes

    2013-01-01

    Full Text Available It is nowadays evident that the West’s civilising, eugenic zeal have had a devastating impact on all aspects of the Indigenous-Australian community tissue, not least the lasting trauma of the Stolen Generations. The latter was the result of the institutionalisation, adoption, fostering, virtual slavery and sexual abuse of thousands of mixed-descent children, who were separated at great physical and emotional distances from their Indigenous kin, often never to see them again. The object of State and Federal policies of removal and mainstream absorption and assimilation between 1930 and 1970, these lost children only saw their plight officially recognised in 1997, when the Bringing Them Home report was published by the Federal government. The victims of forced separation and migration, they have suffered serious trans-generational problems of adaptation and alienation in Australian society, which have been not only documented from the outside in the aforementioned report but also given shape from the inside of and to Indigenous-Australian literature over the last three decades. The following addresses four Indigenous Western-Australian writers within the context of the Stolen Generations, and deals particularly with the semi-biographical fiction by the Nyoongar author Kim Scott, which shows how a very liminal hybrid identity can be firmly written in place yet. Un-writing past policies of physical and ‘epistemic’ violence on the Indigenous Australian population, his fiction addresses a way of approaching Australianness from an Indigenous perspective as inclusive, embracing transculturality within the nation-space.

  16. Concept development of "compassion fatigue" in clinical nurses: Application of Schwartz-Barcott and Kim's hybrid model

    Directory of Open Access Journals (Sweden)

    Mahdieh Sabery

    2017-06-01

    Full Text Available Compassion fatigue is not a new concept in nursing; yet, it is not well known and there is no fixed clear definition of the term. The ambiguity surrounding how to define compassion fatigue has challenged its measurement and evaluation. Thus, any attempt to determine attributes of this underdeveloped concept and studying it in a new socio-cultural context requires concept development. The purpose of this study is to clarify the concept of compassion fatigue through concept development and to produce a vivid and tentative definition of this concept in clinical practice. Concept development was conducted using a three-step hybrid concept analysis including theoretical, fieldwork, and final analysis phases according to Schwartz-Barcott and Kim's method. We reviewed and analyzed 48 articles that met the inclusion criteria. Following, the first author conducted 13 interviews with clinical nurses followed by an inductive content analysis. Finally, a comprehensive definition of compassion fatigue in nurses was attained. Compassion fatigue in nurses can be explained as a cumulative and progressive process of absorption of the patient’s pain and suffering formed from the sympathetic and caring interactions with the patients and their families. The physical, emotional, intellectual, spiritual, social, and organizational consequences of compassion fatigue are so extensive that they threaten the existential integrity of the nurse. Context-based variables (culture, family, and community such as personality features like devotion behaviors and commitment towards the patient, exposure to multiple stressors, organizational challenges, and lack of self-care are factors associated with an increased risk of compassion fatigue. Concept development of compassion fatigue is the first step in the protection of nurses against the destructive consequences of compassion fatigue and to improve quality of care.

  17. Epidermal or dermal specific knockout of PHD-2 enhances wound healing and minimizes ischemic injury.

    Directory of Open Access Journals (Sweden)

    Andrew S Zimmermann

    Full Text Available INTRODUCTION: Hypoxia-inducible factor (HIF-1α, part of the heterodimeric transcription factor that mediates the cellular response to hypoxia, is critical for the expression of multiple angiogenic growth factors, cell motility, and the recruitment of endothelial progenitor cells. Inhibition of the oxygen-dependent negative regulator of HIF-1α, prolyl hydroxylase domain-2 (PHD-2, leads to increased HIF-1α and mimics various cellular and physiological responses to hypoxia. The roles of PHD-2 in the epidermis and dermis have not been clearly defined in wound healing. METHODS: Epidermal and dermal specific PHD-2 knockout (KO mice were developed in a C57BL/6J (wild type background by crossing homozygous floxed PHD-2 mice with heterozygous K14-Cre mice and heterozygous Col1A2-Cre-ER mice to get homozygous floxed PHD-2/heterozygous K14-Cre and homozygous floxed PHD-2/heterozygous floxed Col1A2-Cre-ER mice, respectively. Ten to twelve-week-old PHD-2 KO and wild type (WT mice were subjected to wounding and ischemic pedicle flap model. The amount of healing was grossly quantified with ImageJ software. Western blot and qRT-PCR was run on protein and RNA from primary cells cultured in vitro. RESULTS: qRT-PCR demonstrated a significant decrease of PHD-2 in keratinocytes and fibroblasts derived from tissue specific KO mice relative to control mice (*p<0.05. Western blot analysis showed a significant increase in HIF-1α and VEGF protein levels in PHD-2 KO mice relative to control mice (*p<0.05. PHD-2 KO mice showed significantly accelerated wound closure relative to WT (*p<0.05. When ischemia was analyzed at day nine post-surgery in a flap model, the PHD-2 tissue specific knockout mice showed significantly more viable flaps than WT (*p<0.05. CONCLUSIONS: PHD-2 plays a significant role in the rates of wound healing and response to ischemic insult in mice. Further exploration shows PHD-2 KO increases cellular levels of HIF-1α and this increase leads to the

  18. Analysis of PhD study at the Medical Faculty, University of Ljubljana, in the years 1995–2010

    Directory of Open Access Journals (Sweden)

    Danijel Petrovič

    2012-12-01

    Full Text Available Besides teaching, research is one of the main activities of the Faculty of Medicine of the University of Ljubljana. Since 1995, the PhD study at the Faculty of Medicine has been organized via the Biomedicine university programme. The authors performed the analysis of the quality of Biomedicine PhD study at the Faculty of Medicine between the years 1995 and 2010. The authors were interested in the number of PhD students that started and finished their PhD studies and how successful PhD students were during that period (how many papers they wrote on the topic of the PhD and what was the impact factor of the papers. In the 15-year period from 1995–2010, 702 students started the Biomedicine PhD programme, while 652 students completed it. Most PhD students (70.7 % have written one SCI paper related to the thesis. Finally, the medium impact factor of the SCI paper related to the PhD thesis was 2.6. We may conclude that the quality of PhD theses evaluated according to the impact factor of the SCI papers related to the theses is solid, however our strength should be aimed toward the continuous increase of quality. In this regard, PhD candidates, mentors as well as the commission for the evaluation of PhD theses must do their homework diligently.

  19. Commentary on "Otolaryngology-head and neck surgery physician workforce issues an analysis for future specialty planning" by Kim, Cooper, and Kennedy.

    Science.gov (United States)

    Pryor, Shannon P; Brodsky, Linda; Chandrasekhar, Sujana S; Zaretsky, Lauren; Taylor, Duane J; Yaremchuk, Kathleen L; Pillsbury, Harold C

    2012-02-01

    An impending physician shortage has been projected. The article by Kim, Cooper, and Kennedy, titled "Otolaryngology-Head and Neck Surgery Physician Workforce Issues: An Analysis for Future Specialty Planning," is an attempt to evaluate and address this potential shortage as it applies to otolaryngology. The authors of this comment have concerns about the article's assumptions, design, and recommendations. Kim et al attempt to extrapolate data from other specialties and other countries to the US otolaryngology workforce, use that data in modeling methods without demonstrated validity, and based on their analysis, they recommend drastic changes to otolaryngologic training and practice in the United States. Particularly troublesome are (1) the emphasis placed on gender and part-time work and (2) the measurement of productivity defined as hours worked per week. Before redefining our specialty, more thorough and systematic data acquisition and review are necessary to meet the needs of our patients now and in the future.

  20. Seventy Years' Dance-Life of Kim Chun-heung(Abstract)%金千兴《心韶金千兴舞乐七十年》节选

    Institute of Scientific and Technical Information of China (English)

    金千兴; 奚治茹

    2011-01-01

    This paper,through retrospection of Kim Chun-heung's career as Korean traditional musical dance master,introduces the establishment of Korean National Music since the founding of South Korea,Kim Chun-heung Classical Dance Institute as well as Korean Masks%本文通过韩国著名传统乐舞大师金千兴先生艺术生涯的回顾,介绍了韩国建国后其大韩国乐的创建以及金千兴古典舞蹈研究所、韩国假面具保存会的开设,并通过金千兴先生恢复韩国传统宫中舞的经历介绍了韩国传统舞蹈及其保护的情况。

  1. Evaluation of objectivity, reliability and criterion validity of the key indicator method for manual handling operations (KIM-MHO), draft 2007.

    Science.gov (United States)

    Klußmann, André; Gebhardt, Hansjürgen; Rieger, Monika; Liebers, Falk; Steinberg, Ulf

    2012-01-01

    Upper extremity musculoskeletal symptoms and disorders are common in the working population. The economic and social impact of such disorders is considerable. Long-time, dynamic repetitive exposure of the hand-arm system during manual handling operations (MHO) alone or in combination with static and postural effort are recognised as causes of musculoskeletal symptoms and disorders. The assessment of these manual work tasks is crucial to estimate health risks of exposed employees. For these work tasks, a new method for the assessment of the working conditions was developed and a validation study was performed. The results suggest satisfying criterion validity and moderate objectivity of the KIM-MHO draft 2007. The method was modified and evaluated again. It is planned to release a new version of KIM-MHO in spring 2012.

  2. Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu) among Agricultural Communities in Sri Lanka.

    Science.gov (United States)

    De Silva, Pallagae Mangala C S; Mohammed Abdul, Khaja Shameem; Eakanayake, Eakanayake M D V; Jayasinghe, Sudheera Sammanthi; Jayasumana, Channa; Asanthi, Hewa Bandulage; Perera, Hettiarachigae S D; Chaminda, Gamage G Tushara; Chandana, Ediriweera P S; Siribaddana, Sisira H

    2016-09-01

    Chronic Kidney Disease of uncertain etiology (CKDu) is an emerging epidemic among farming communities in rural Sri Lanka. Victims do not exhibit common causative factors, however, histopathological studies revealed that CKDu is a tubulointerstitial disease. Urine albumin or albumin-creatinine ratio is still being used as a traditional diagnostic tool to identify CKDu, but accuracy and prevalence data generated are questionable. Urinary biomarkers have been used in similar nephropathy and are widely recognised for their sensitivity, specificity and accuracy in determining CKDu and early renal injury. However, these biomarkers have never been used in diagnosing CKDu in Sri Lanka. Male farmers (n = 1734) were recruited from 4 regions in Sri Lanka i.e. Matara and Nuwara Eliya (farming locations with no CKDu prevalence) and two CKDu emerging locations from Hambantota District in Southern Sri Lanka; Angunakolapelessa (EL1) and Bandagiriya (EL2). Albuminuria (ACR ≥ 30mg/g); serum creatinine based estimation of glomerular filtration rate (eGFR); creatinine normalized urinary kidney injury molecule (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) were measured. Fourteen new CKDu cases (18%) from EL1 and nine CKDu cases (9%) from EL2 were recognized for the first time from EL1, EL2 locations, which were previously considered as non-endemic of the disease and associated with persistent albuminuria (ACR ≥ 30mg/g Cr). No CKDu cases were identified in non-endemic study locations in Matara (CM) and Nuwara Eliya (CN). Analysis of urinary biomarkers showed urinary KIM-1 and NGAL were significantly higher in new CKDu cases in EL1 and EL2. However, we also reported significantly higher KIM-1 and NGAL in apparently healthy farmers in EL 1 and EL 2 with comparison to both control groups. These observations may indicate possible early renal damage in absence of persistent albuminuria and potential capabilities of urinary KIM-1 and NGAL in early detection of renal injury

  3. Can You Anchor a Shimmering Nation State via Regional Indigenous Roots? Kim Scott talks to Anne Brewster about That Deadman Dance

    Directory of Open Access Journals (Sweden)

    Anne Brewster

    2011-10-01

    Full Text Available This interview focuses mainly on Kim Scott’s new novel That Deadman Dance which won the regional Commonwealth Writers Prize (Southeast Asian and Pacific region and the Miles Franklin Award. The topics of conversation include Scott’s involvement in the Noongar language project (and the relationship of this project to the novel, the novel itself, the challenges of writing in English, the resistance paradigm and indigenous sovereignty and nationalism.

  4. Beaudrie, Sara, Ducar, Cynthia, & Potowski, Kim (2014). Heritage language teaching: Research and practice. New York State, New York: McGraw Hill.

    OpenAIRE

    Florencia Henshaw

    2015-01-01

    This review introduces readers to Heritage language teaching: Research and practice, by Sara Beaudrie, Cynthia Ducar, and Kim Potowski, which is part of the “Directions in Second Language Learning” series. This handbook offers a comprehensive overview of key concepts, research findings, and pedagogical strategies to better meet the needs of heritage learners, and it underscores the importance of sociolinguistic issues and phenomena in heritage language instruction.

  5. Beaudrie, Sara, Ducar, Cynthia, & Potowski, Kim (2014. Heritage language teaching: Research and practice. New York State, New York: McGraw Hill.

    Directory of Open Access Journals (Sweden)

    Florencia Henshaw

    2015-12-01

    Full Text Available This review introduces readers to Heritage language teaching: Research and practice, by Sara Beaudrie, Cynthia Ducar, and Kim Potowski, which is part of the “Directions in Second Language Learning” series. This handbook offers a comprehensive overview of key concepts, research findings, and pedagogical strategies to better meet the needs of heritage learners, and it underscores the importance of sociolinguistic issues and phenomena in heritage language instruction.

  6. I-determinants for a successful PhD or postdoctoral outcome

    Directory of Open Access Journals (Sweden)

    Sørensen HT

    2016-08-01

    Full Text Available Henrik Toft Sørensen1–3 1Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus N, Denmark; 2Department of Health Research and Policy, 3Stanford’s Center for Advanced Study in Behavioral Sciences, Stanford University, Stanford, CA, USA Abstract: Many resources are invested in research training, but very little literature exists on predictors for a successful PhD and postdoctoral training outcome. A PhD program has two overall objectives: to extend knowledge about a hopefully important health topic and to provide extensive training to improve the PhD student’s skills through learning research methods and collaboration. A substantial number of PhD students may run into some kind of problem in the course of their PhD program. In this article, some determinants all starting with an “I” and indicative of a good PhD outcome are reported. The successful PhD student can be described as having an Interest in the PhD program, an Incentive for the program, and an Idea of what he or she wants to investigate, showing Initiative, and having high personal Integrity and good Interpersonal relationships. When these so-called I-determinants are present, the likelihood of success in a PhD program is high. More evidence is available for selection of candidates for postdoctoral appointments since it is known that the postdoctoral candidate has completed a PhD program, published papers in peer-reviewed journals, and received awarded grants. However, other characteristics determine a successful transition of the postdoctoral candidate into a research leader. These determinants are Identity, Independence and Image, Implementation ability in terms of being able to implement decisions and projects, working with Innovative and Important topics, having In-depth knowledge of the research topic, being Interactive and Integrated with the scientific community, and Internationally oriented. In conclusion, regardless of the framework of research, the

  7. Soybean GmPHD-Type Transcription Regulators Improve Stress Tolerance in Transgenic Arabidopsis Plants

    OpenAIRE

    Wei Wei; Jian Huang; Yu-Jun Hao; Hong-Feng Zou; Hui-Wen Wang; Jing-Yun Zhao; Xue-Yi Liu; Wan-Ke Zhang; Biao Ma; Jin-Song Zhang; Shou-Yi Chen

    2009-01-01

    BACKGROUND: Soybean [Glycine max (L.) Merr.] is one of the most important crops for oil and protein resource. Improvement of stress tolerance will be beneficial for soybean seed production. PRINCIPAL FINDINGS: Six GmPHD genes encoding Alfin1-type PHD finger protein were identified and their expressions differentially responded to drought, salt, cold and ABA treatments. The six GmPHDs were nuclear proteins and showed ability to bind the cis-element "GTGGAG". The N-terminal domain of GmPHD play...

  8. KIMS, CEDIA, and HS-CEDIA immunoassays are inadequately sensitive for detection of benzodiazepines in urine from patients treated for chronic pain.

    Science.gov (United States)

    Darragh, Alicia; Snyder, Marion L; Ptolemy, Adam S; Melanson, Stacy

    2014-01-01

    Patients treated for chronic pain may frequently undergo urine drug testing to monitor medication compliance and detect undisclosed prescribed or illicit drug use. Due to the increasing use and abuse of benzodiazepines, this class of medications is often included in drug screening panels. However, immunoassay-based methods lack the requisite sensitivity for detecting benzodiazepine use in this population primarily due to their poor cross-reactivity with several major urinary benzodiazepine metabolites. A High Sensitivity Cloned Enzyme Donor Immunoassay (HS-CEDIA), in which beta-glucuronidase is added to the reagent, has been shown to perform better than traditional assays, but its performance in patients treated for chronic pain is not well characterized. To determine the diagnostic accuracy of HS-CEDIA, as compared to the Cloned Enzyme Donor Immunoassay (CEDIA) and Kinetic Interaction of Microparticles in Solution (KIMS) screening immunoassays and liquid chromatography-tandem mass spectrometry (LC-MS/MS), for monitoring benzodiazepine use in patients treated for chronic pain. A study of the diagnostic accuracy of urine benzodiazepine immunoassays. The study was conducted at an academic tertiary care hospital with a clinical laboratory that performs urine drug testing for monitoring medication compliance in pain management. A total of 299 urine specimens from patients treated for chronic pain were screened for the presence of benzodiazepines using the HS-CEDIA, CEDIA, and KIMS assays. The sensitivity and specificity of the screening assays were determined using the LC-MS/MS results as the reference method. Of the 299 urine specimens tested, 141 (47%) confirmed positive for one or more of the benzodiazepines/metabolites by LC-MS/MS. All 3 screens were 100% specific with no false-positive results. The CEDIA and KIMS sensitivities were 55% (78/141) and 47% (66/141), respectively. Despite the relatively higher sensitivity of the HS-CEDIA screening assay (78%; 110

  9. The Virtual Observatory Powered PhD Thesis

    Science.gov (United States)

    Zolotukhin, I. Yu.

    2010-12-01

    The Virtual Observatory has reached sufficient maturity for its routine scientific exploitation by astronomers. To prove this statement, here I present a brief description of the complete VO-powered PhD thesis entitled “Galactic and extragalactic research with modern surveys and the Virtual Observatory” comprising 4 science cases covering various aspects of astrophysical research. These comprize: (1) homogeneous search and measurement of main physical parameters of Galactic open star clusters in huge multi-band photometric surveys; (2) study of optical-to-NIR galaxy colors using a large homogeneous dataset including spectroscopy and photometry from SDSS and UKIDSS; (3) study of faint low-mass X-ray binary population in modern observational archives; (4) search for optical counterparts of unidentified X-ray objects with large positional uncertainties in the Galactic Plane. All these projects make heavy use of the VO technologies and tools and would not be achievable without them. So refereed papers published in the frame of this thesis can undoubtedly be added to the growing list of VO-based research works.

  10. The JIM interview. Art Levinson, PhD.

    Science.gov (United States)

    Levinson, A

    1997-06-01

    In the early 1980s several prominent scientists left the hallowed halls of respected universities seeking to exploit the revolution occurring in biology in an environment devoid of the bureaucratic and political confines of academia. The emergence of the biotechnology industry has been marked by both spectacular failures and success stories. Genentech was founded in 1976 by biochemist Herbert Boyer and venture capitalist Robert Swanson and went public in 1980. In 1995 Genentech merged with Roche Holdings Ltd., of Basel Switzerland. Distinguished from other biotech companies by the varied array of products it has brought to market, Genentech has also developed a unique corporate culture embodying many traditional academic values. Just as Genentech went public in 1980, Arthur D. Levinson, PhD, finished a post-doctoral appointment in Michael Bishop's lab at the University of California, San Francisco. Despite the disapproval of colleagues, he joined the fledgling company as a senior scientist. Working his way though the ranks, Levinson became Vice President of Research Technology in 1989 and was named President and CEO in 1995. Interviewed at the sprawling corporate headquarters in South San Francisco, Levinson reflected on the process of high risk science, the benefits of the private sector, and the changing relationship between biotech companies and the academic world.

  11. Middle School Sports Teaching Reform Based on the "Sunny Sports"%“阳光体育运动”背景下中学体育教学改革探究

    Institute of Scientific and Technical Information of China (English)

    陈晓利; 游贵兵; 高卫民; 郝宏钟

    2011-01-01

    青少年是祖国的未来,民族的希望,他们的身体健康关系到国家未来的竞争力,但我国青少年的体质健康状况却不容乐观。为了改善青少年的体质健康状况,2007年4月,教育部、国家体育总局、共青团中央在全国范围内全面启动了"阳光体育运动"。"阳光体育运动"是国家在新时期促进中学生身心健康发展的战略性举措,包含了很多与时俱进的教育思想和理念,对传统体育教学带来巨大挑战,传统体育教学势必要进行相应改革以适应"阳光体育运动"的开展。文章采用文献资料法和逻辑分析法,指出了传统体育教学存在的问题,并以"阳光体育运动"为背景提出了相应改革措施。%Teenagers are the future of one country and the hope of one nation.Their physical quality affects the competitive power of one country.However,the physical quality of China's teenagers is not so good.In order to improve the physical quality of teenagers,in April 2007,the Ministry of Education,State General Administration of Sports and the Central Committee of the Communist Youth League launched Sunny Sports nationwide.Sunny Sports is a national strategic movement to promote physical and mental health of middle school student.It reflects many latest education ideas and philosophy.Thus,traditional sports teaching must be reformed in order to meet the development of Sunny Sports.By using methods of literature review and logical analysis,the paper pointed out the problems of traditional sports teaching and offered some reform measures based on the Sunny Sports.

  12. Improved Bearings-Only Multi-Target Tracking with GM-PHD Filtering

    Science.gov (United States)

    Zhang, Qian; Song, Taek Lyul

    2016-01-01

    In this paper, an improved nonlinear Gaussian mixture probability hypothesis density (GM-PHD) filter is proposed to address bearings-only measurements in multi-target tracking. The proposed method, called the Gaussian mixture measurements-probability hypothesis density (GMM-PHD) filter, not only approximates the posterior intensity using a Gaussian mixture, but also models the likelihood function with a Gaussian mixture instead of a single Gaussian distribution. Besides, the target birth model of the GMM-PHD filter is assumed to be partially uniform instead of a Gaussian mixture. Simulation results show that the proposed filter outperforms the GM-PHD filter embedded with the extended Kalman filter (EKF) and the unscented Kalman filter (UKF). PMID:27626423

  13. Role of PHD fingers and COOH-terminal 30 amino acids in AIRE transactivation activity.

    Science.gov (United States)

    Meloni, Alessandra; Incani, Federica; Corda, Denise; Cao, Antonio; Rosatelli, Maria Cristina

    2008-02-01

    Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare autosomic autoimmune disease resulting from the defective function of a gene codifying for a transcription factor named autoimmune regulation (AIRE). The AIRE protein contains several domains among which two PHD fingers involved in the transcriptional activation. We investigated the function of the two PHD finger domains and the COOH terminal portion of AIRE by using several mutated constructs transfected in mammalian cells and a luciferase reporter assay. The results predict that the second PHD as well as the COOH terminal regions have marked transactivational properties. The COOH terminal region contains the fourth LXXLL and the PXXPXP motifs which play a critical role in mediating the transactivation capacity of the AIRE protein. Our study provides a definition of the role of the PHD fingers in transactivation and identifies a new transactivation domain of the AIRE protein localized in the COOH terminal region.

  14. Actualization of the PhD Students' Intercultural Research Competencies in Global Society

    Directory of Open Access Journals (Sweden)

    Inga Dailidiene

    2013-12-01

    Full Text Available globalization is changing the qualitative characteristics of society, affecting both the life and mentality of people. In relevance to globalization, higher education is gaining new dimensions as well. Bologna and Lisbon documents guide and obligate each country to create integrated and harmonious international space of higher education in Europe. phd studies are considered as integral in the higher education structure; therefore, internationalization is a significant imperative for phd studies development. In the process of internationalization, the need for students’ intercultural competencies is widely recognized. Firstly, we suppose that the impact of globalization on internationalization still remains underestimated. Globalization makes internationalization not only more intense, but also qualitatively different. Secondly, there is a lack of systemic analysis on the development of intercultural research competencies in phd studies. We relate the need for intercultural research competencies to the following critical and rhetorical question: ‘Are today’s phd students ready to solve tomorrow’s global problems?’

  15. A New Venture in Graduate Education: Co-Op Ph.D. Programme in Chemical Engineering.

    Science.gov (United States)

    Fahidy, Thomas Z.

    1980-01-01

    Describes a cooperative Ph.D. program at the University of Waterloo, Ontario, Canada, in which industrial and governmental employers participate with the Department of Chemical Engineering in training chemical engineers. (CS)

  16. Doc of prophage P1 is inhibited by its antitoxin partner Phd through fold complementation

    DEFF Research Database (Denmark)

    Garcia-Pino, Abel; Christensen-Dalsgaard, Mikkel; Wyns, Lode

    2008-01-01

    evolutionary origin for the phd/doc operon. Doc induces growth arrest of Escherichia coli cells in a reversible manner, by targeting the protein synthesis machinery. Moreover, Doc activates the endogenous E. coli RelE mRNA interferase but does not require this or any other known chromosomal toxin......Prokaryotic toxin-antitoxin modules are involved in major physiological events set in motion under stress conditions. The toxin Doc (death on curing) from the phd/doc module on phage P1 hosts the C-terminal domain of its antitoxin partner Phd (prevents host death) through fold complementation....... This Phd domain is intrinsically disordered in solution and folds into an alpha-helix upon binding to Doc. The details of the interactions reveal the molecular basis for the inhibitory action of the antitoxin. The complex resembles the Fic (filamentation induced by cAMP) proteins and suggests a possible...

  17. PhD Wang Xingchu,A Successful Leader of A High-tech Company Reform

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ PhD Wang Xingchu was born in 1962. He is the Board Chairman of Shanghai Biotechnology Industrial Garden Coalition Development Co., Ltd. and the General Manager of Shanghai Hua Xin High-Biotechnology Co., Ltd.

  18. Improved Bearings-Only Multi-Target Tracking with GM-PHD Filtering

    Directory of Open Access Journals (Sweden)

    Qian Zhang

    2016-09-01

    Full Text Available In this paper, an improved nonlinear Gaussian mixture probability hypothesis density (GM-PHD filter is proposed to address bearings-only measurements in multi-target tracking. The proposed method, called the Gaussian mixture measurements-probability hypothesis density (GMM-PHD filter, not only approximates the posterior intensity using a Gaussian mixture, but also models the likelihood function with a Gaussian mixture instead of a single Gaussian distribution. Besides, the target birth model of the GMM-PHD filter is assumed to be partially uniform instead of a Gaussian mixture. Simulation results show that the proposed filter outperforms the GM-PHD filter embedded with the extended Kalman filter (EKF and the unscented Kalman filter (UKF.

  19. Trends in landscape research and landscape planning : implications for PhD students

    NARCIS (Netherlands)

    Tress, G.; Tress, B.; Fry, G.; Antrop, M.

    2005-01-01

    This chapter introduces the contents of the book through an analysis of current trends in landscape research and landscape planning and a discussion of the consequences of these trends for PhD students.

  20. Articulating Expectations for PhD Candidature upon Commencement: Ensuring Supervisor/Student "Best Fit"

    Science.gov (United States)

    Moxham, Lorna; Dwyer, Trudy; Reid-Searl, Kerry

    2013-01-01

    The journey towards completion of a PhD is a bumpy one for many. One of the major factors that influence successful and on-time thesis completion is the relationship that the PhD candidate has with her or his supervisor. This paper presents results from research undertaken using a 12-item survey to collect data from a purposive sample: PhD…

  1. Skill development in collaborative research projects: A comparison between PhD students in multi-actor research programs and in traditional trajectories

    NARCIS (Netherlands)

    Wardenaar, T.; Belder, R.; de Goede, M.E.E; Horlings, E.; van den Besselaar, P.

    2014-01-01

    The growing number of PhD students has spurred debates about the societal relevance of PhD training trajectories. The academic labour market does not provide enough jobs and many PhD graduates will have a career outside academia. It has been questioned whether current PhD training trajectories are s

  2. Skill development in collaborative research projects: A comparison between PhD students in multi-actor research programs and in traditional trajectories

    NARCIS (Netherlands)

    Wardenaar, T.; Belder, R.; de Goede, M.E.E; Horlings, E.; van den Besselaar, P.

    2014-01-01

    The growing number of PhD students has spurred debates about the societal relevance of PhD training trajectories. The academic labour market does not provide enough jobs and many PhD graduates will have a career outside academia. It has been questioned whether current PhD training trajectories are s

  3. MS PHD'S: Effective Strategies for the Retention and Advancement of URM Students in ESS

    Science.gov (United States)

    Escalera, J.; Burgess, A. K.; Pace, L.; Scott, O.; Strickland, J.; Johnson, A.; Williamson Whitney, V.; Ithier-Guzman, W.

    2012-12-01

    The Minorities Striving and Pursuing Higher Degrees of Success (MS PHD'S) Professional Development Program in Earth system science (ESS) is a model initiative for improving the retention of underrepresented minority (URM) students in STEM fields. Entering its ninth cohort, MS PHD'S remains committed to helping URM undergraduate and graduate students achieve outstanding careers in ESS. MS PHD'S facilitates URM student achievement through a three-phase program designed to increase student exposure to the ESS community. By engaging in a series of professional development and skill building exercises, peer-to-peer community building activities, participation in scientific society conferences and workshops, mentoring by URM and other scientists, and a virtual community, URM students gain the confidence and support necessary to achieve their academic goals and enter the ESS workforce. Since its inception, MS PHD'S continues to support 189 participants. Of these 189 participants, 35 have advanced from undergraduate and graduate academic pathways to completion of their PhD and another 60 are currently enrolled in doctoral programs. MS PHD'S maintains close ties with program alumni to further support retention, inclusivity, and broadening participation of URM students and graduates in STEM activities. Its model is built on reengaging alumni to become mentors and leaders for each new cohort as well as facilitating valuable opportunities for alumni to advance in their ESS related academic and professional career pathways.

  4. Structure of human Sp140 PHD finger: an atypical fold interacting with Pin1.

    Science.gov (United States)

    Zucchelli, Chiara; Tamburri, Simone; Quilici, Giacomo; Palagano, Eleonora; Berardi, Andrea; Saare, Mario; Peterson, Pärt; Bachi, Angela; Musco, Giovanna

    2014-01-01

    Sp140 is a nuclear leukocyte-specific protein involved in primary biliary cirrhosis and a risk factor in chronic lymphocytic leukemia. The presence of several chromatin related modules such as plant homeodomain (PHD), bromodomain and SAND domain suggests a role in chromatin-mediated regulation of gene expression; however, its real function is still elusive. Herein we present the solution structure of Sp140-PHD finger and investigate its role as epigenetic reader in vitro. Sp140-PHD presents an atypical PHD finger fold which does not bind to histone H3 tails but is recognized by peptidylprolyl isomerase Pin1. Pin1 specifically binds to a phosphopeptide corresponding to the L3 loop of Sp140-PHD and catalyzes cis-trans isomerization of a pThr-Pro bond. Moreover co-immunoprecipitation experiments demonstrate FLAG-Sp140 interaction with endogenous Pin1 in vivo. Overall these data include Sp140 in the list of the increasing number of Pin1 binders and expand the regulatory potential of PHD fingers as versatile structural platforms for diversified interactions. © 2013 FEBS.

  5. Solution NMR structure and histone binding of the PHD domain of human MLL5.

    Directory of Open Access Journals (Sweden)

    Alexander Lemak

    Full Text Available Mixed Lineage Leukemia 5 (MLL5 is a histone methyltransferase that plays a key role in hematopoiesis, spermatogenesis and cell cycle progression. In addition to its catalytic domain, MLL5 contains a PHD finger domain, a protein module that is often involved in binding to the N-terminus of histone H3. Here we report the NMR solution structure of the MLL5 PHD domain showing a variant of the canonical PHD fold that combines conserved H3 binding features from several classes of other PHD domains (including an aromatic cage along with a novel C-terminal α-helix, not previously seen. We further demonstrate that the PHD domain binds with similar affinity to histone H3 tail peptides di- and tri-methylated at lysine 4 (H3K4me2 and H3K4me3, the former being the putative product of the MLL5 catalytic reaction. This work establishes the PHD domain of MLL5 as a bone fide 'reader' domain of H3K4 methyl marks suggesting that it may guide the spreading or further methylation of this site on chromatin.

  6. Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle.

    Science.gov (United States)

    Suhara, Tomohiro; Hishiki, Takako; Kasahara, Masataka; Hayakawa, Noriyo; Oyaizu, Tomoko; Nakanishi, Tsuyoshi; Kubo, Akiko; Morisaki, Hiroshi; Kaelin, William G; Suematsu, Makoto; Minamishima, Yoji Andrew

    2015-09-15

    Loss of prolyl hydroxylase 2 (PHD2) activates the hypoxia-inducible factor-dependent hypoxic response, including anaerobic glycolysis, which causes large amounts of lactate to be released from cells into the circulation. We found that Phd2-null mouse embryonic fibroblasts (MEFs) produced more lactate than wild-type MEFs, as expected, whereas systemic inactivation of PHD2 in mice did not cause hyperlacticacidemia. This unexpected observation led us to hypothesize that the hypoxic response activated in the liver enhances the Cori cycle, a lactate-glucose carbon recycling system between muscle and liver, and thereby decreases circulating lactate. Consistent with this hypothesis, blood lactate levels measured after a treadmill or lactate tolerance test were significantly lower in Phd2-liver-specific knockout (Phd2-LKO) mice than in control mice. An in vivo (13)C-labeled lactate incorporation assay revealed that the livers of Phd2-LKO mice produce significantly more glucose derived from (13)C-labeled lactate than control mice, suggesting that blockade of PHD2 in the liver ameliorates lactic acidosis by activating gluconeogenesis from lactate. Phd2-LKO mice were resistant to lactic acidosis induced by injection of a lethal dose of lactate, displaying a significant elongation of survival. Moreover, oral administration of a PHD inhibitor improved survival in an endotoxin shock mice model. These data suggest that PHD2 is a potentially novel drug target for the treatment of lactic acidosis, which is a serious and often fatal complication observed in some critically ill patients.

  7. From Doctoral Student To Faculty Member: PhD. Project Alumni’s Evaluation Of Their Preparedness

    Directory of Open Access Journals (Sweden)

    Bill N. Schwartz

    2012-03-01

    Full Text Available In response to the important issues regarding diversity in business schools and corporate America, the KPMG Foundation established the PhD Project. The PhD Project helps business professionals and recent college graduates earn doctoral degrees in business disciplines and join business school faculty. While the PhD Project has helped increase the number of minority faculty members in business schools, it may be helpful to gather insights from the recent PhD alumni who have received support from the PhD Project. Our study examines attitudes about preparedness of PhD Project alums for their first faculty position after completing their PhD program. Results show that PhD Project alumni and majority PhD alumni (alumni not associated with the PhD Project felt they were prepared for their first faculty position, but they were not significantly different in their evaluation in most respects. However, to our surprise, majority PhD alumni felt they were better prepared for research than PhD Project alumni. This difference was significant and further analyses showed that younger faculty and those in the ethnic majority were better prepared for research. Both groups considered themselves well prepared for research and teaching. Neither group was as optimistic about being prepared for service responsibilities and the academic climate or politics of an academic career. Our findings show that the PhD Project is necessary to help ensure that minority faculty members are adequately prepared for research and their academic careers.

  8. Preparing for Graduate-Level Training in Professional Psychology: Comparisons across Clinical PhD, Counseling PhD, and Clinical PsyD Programs

    Science.gov (United States)

    Karazsia, Bryan T.; Smith, Lena

    2016-01-01

    In the present study, faculty who teach in clinical and counseling doctor of philosophy (PhD) or doctor of psychology (PsyD) programs completed surveys regarding preferences for prospective student preparations to graduate programs. Faculty expectations of minimum and ideal undergraduate training were highest for scientific methods, though…

  9. Preparing for Graduate-Level Training in Professional Psychology: Comparisons across Clinical PhD, Counseling PhD, and Clinical PsyD Programs

    Science.gov (United States)

    Karazsia, Bryan T.; Smith, Lena

    2016-01-01

    In the present study, faculty who teach in clinical and counseling doctor of philosophy (PhD) or doctor of psychology (PsyD) programs completed surveys regarding preferences for prospective student preparations to graduate programs. Faculty expectations of minimum and ideal undergraduate training were highest for scientific methods, though…

  10. Professional Socialization for the Ph.D.: An Exploration of Career and Professional Development Preparedness and Readiness for Ph.D. Candidates

    Science.gov (United States)

    Helm, Matt; Campa, Henry, III; Moretto, Kristin

    2012-01-01

    This study sought to uncover the career readiness and professional development needs of Ph.D. students at a large, Midwestern research university. Findings indicate that career goals of graduate students change over time, skill preparation for academic and non-academic careers continues to be inadequate for many students and professional…

  11. Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu among Agricultural Communities in Sri Lanka.

    Directory of Open Access Journals (Sweden)

    Pallagae Mangala C S De Silva

    2016-09-01

    Full Text Available Chronic Kidney Disease of uncertain etiology (CKDu is an emerging epidemic among farming communities in rural Sri Lanka. Victims do not exhibit common causative factors, however, histopathological studies revealed that CKDu is a tubulointerstitial disease. Urine albumin or albumin-creatinine ratio is still being used as a traditional diagnostic tool to identify CKDu, but accuracy and prevalence data generated are questionable. Urinary biomarkers have been used in similar nephropathy and are widely recognised for their sensitivity, specificity and accuracy in determining CKDu and early renal injury. However, these biomarkers have never been used in diagnosing CKDu in Sri Lanka. Male farmers (n = 1734 were recruited from 4 regions in Sri Lanka i.e. Matara and Nuwara Eliya (farming locations with no CKDu prevalence and two CKDu emerging locations from Hambantota District in Southern Sri Lanka; Angunakolapelessa (EL1 and Bandagiriya (EL2. Albuminuria (ACR ≥ 30mg/g; serum creatinine based estimation of glomerular filtration rate (eGFR; creatinine normalized urinary kidney injury molecule (KIM-1 and neutrophil gelatinase-associated lipocalin (NGAL were measured. Fourteen new CKDu cases (18% from EL1 and nine CKDu cases (9% from EL2 were recognized for the first time from EL1, EL2 locations, which were previously considered as non-endemic of the disease and associated with persistent albuminuria (ACR ≥ 30mg/g Cr. No CKDu cases were identified in non-endemic study locations in Matara (CM and Nuwara Eliya (CN. Analysis of urinary biomarkers showed urinary KIM-1 and NGAL were significantly higher in new CKDu cases in EL1 and EL2. However, we also reported significantly higher KIM-1 and NGAL in apparently healthy farmers in EL 1 and EL 2 with comparison to both control groups. These observations may indicate possible early renal damage in absence of persistent albuminuria and potential capabilities of urinary KIM-1 and NGAL in early detection of renal

  12. A PHD-polycomb repressive complex 2 triggers the epigenetic silencing of FLC during vernalization.

    Science.gov (United States)

    De Lucia, Filomena; Crevillen, Pedro; Jones, Alexandra M E; Greb, Thomas; Dean, Caroline

    2008-11-04

    Vernalization, the acceleration of flowering by winter, involves cold-induced epigenetic silencing of Arabidopsis FLC. This process has been shown to require conserved Polycomb Repressive Complex 2 (PRC2) components including the Su(z)12 homologue, VRN2, and two plant homeodomain (PHD) finger proteins, VRN5 and VIN3. However, the sequence of events leading to FLC repression was unclear. Here we show that, contrary to expectations, VRN2 associates throughout the FLC locus independently of cold. The vernalization-induced silencing is triggered by the cold-dependent association of the PHD finger protein VRN5 to a specific domain in FLC intron 1, and this association is dependent on the cold-induced PHD protein VIN3. In plants returned to warm conditions, VRN5 distribution changes, and it associates more broadly over FLC, coincident with significant increases in H3K27me3. Biochemical purification of a VRN5 complex showed that during prolonged cold a PHD-PRC2 complex forms composed of core PRC2 components (VRN2, SWINGER [an E(Z) HMTase homologue], FIE [an ESC homologue], MSI1 [p55 homologue]), and three related PHD finger proteins, VRN5, VIN3, and VEL1. The PHD-PRC2 activity increases H3K27me3 throughout the locus to levels sufficient for stable silencing. Arabidopsis PHD-PRC2 thus seems to act similarly to Pcl-PRC2 of Drosophila and PHF1-PRC2 of mammals. These data show FLC silencing involves changed composition and dynamic redistribution of Polycomb complexes at different stages of the vernalization process, a mechanism with greater parallels to Polycomb silencing of certain mammalian loci than the classic Drosophila Polycomb targets.

  13. Increased EPO Levels Are Associated With Bone Loss in Mice Lacking PHD2 in EPO-Producing Cells.

    Science.gov (United States)

    Rauner, Martina; Franke, Kristin; Murray, Marta; Singh, Rashim Pal; Hiram-Bab, Sahar; Platzbecker, Uwe; Gassmann, Max; Socolovsky, Merav; Neumann, Drorit; Gabet, Yankel; Chavakis, Triantafyllos; Hofbauer, Lorenz C; Wielockx, Ben

    2016-10-01

    The main oxygen sensor hypoxia inducible factor (HIF) prolyl hydroxylase 2 (PHD2) is a critical regulator of tissue homeostasis during erythropoiesis, hematopoietic stem cell maintenance, and wound healing. Recent studies point toward a role for the PHD2-erythropoietin (EPO) axis in the modulation of bone remodeling, even though the studies produced conflicting results. Here, we used a number of mouse strains deficient of PHD2 in different cell types to address the role of PHD2 and its downstream targets HIF-1α and HIF-2α in bone remodeling. Mice deficient for PHD2 in several cell lineages, including EPO-producing cells, osteoblasts, and hematopoietic cells (CD68:cre-PHD2(f/f) ) displayed a severe reduction of bone density at the distal femur as well as the vertebral body due to impaired bone formation but not bone resorption. Importantly, using osteoblast-specific (Osx:cre-PHD2(f/f) ) and osteoclast-specific PHD2 knock-out mice (Vav:cre- PHD2(f/f) ), we show that this effect is independent of the loss of PHD2 in osteoblast and osteoclasts. Using different in vivo and in vitro approaches, we show here that this bone phenotype, including the suppression of bone formation, is directly linked to the stabilization of the α-subunit of HIF-2, and possibly to the subsequent moderate induction of serum EPO, which directly influenced the differentiation and mineralization of osteoblast progenitors resulting in lower bone density. Taken together, our data identify the PHD2:HIF-2α:EPO axis as a so far unknown regulator of osteohematology by controlling bone homeostasis. Further, these data suggest that patients treated with PHD inhibitors or EPO should be monitored with respect to their bone status. © 2016 American Society for Bone and Mineral Research.

  14. PhD students’ expectations from their supervisors: A qualitative content analysis

    Directory of Open Access Journals (Sweden)

    SH Rimaz

    2015-03-01

    Full Text Available Introduction: Quality of research in PhD programs increases if supervisors become aware of students' expectations from them. This qualitative study aimed to explore expectations of PhD students from their supervisors was done.   Methods: This qualitative content analysis study was conducted on 22 graduated PhD students of Iran University of Medical Sciences, in 2014. The samples were purposefully selected and interviewed. All interviews were recorded and transcribed verbatim.   Results: After analyzing and coding data, it was found that PhD students have four main expectations from their supervisors. These expectations consist of scientific support including help with selection of subject, preparation and registration of proposal, data collection and support for writing and examination of the thesis. Developing scientific skills and help with preparing manuscripts were other expectations. Emotional-social support with five categories including relationship between supervisor-student, general expectations of supervisor, supervisor personality characteristics, needed emotional skills and social activities related to thesis and finally providing adequate resources including financial support and access to facilities inside and outside the university were among the other expectations.   Conclusion: PhD students need to scientific, emotional, social and material supports from their supervisors in the process of performing thesis. These expectations should be told to supervisors.

  15. Predicting the "graduate on time (GOT)" of PhD students using binary logistics regression model

    Science.gov (United States)

    Shariff, S. Sarifah Radiah; Rodzi, Nur Atiqah Mohd; Rahman, Kahartini Abdul; Zahari, Siti Meriam; Deni, Sayang Mohd

    2016-10-01

    Malaysian government has recently set a new goal to produce 60,000 Malaysian PhD holders by the year 2023. As a Malaysia's largest institution of higher learning in terms of size and population which offers more than 500 academic programmes in a conducive and vibrant environment, UiTM has taken several initiatives to fill up the gap. Strategies to increase the numbers of graduates with PhD are a process that is challenging. In many occasions, many have already identified that the struggle to get into the target set is even more daunting, and that implementation is far too ideal. This has further being progressing slowly as the attrition rate increases. This study aims to apply the proposed models that incorporates several factors in predicting the number PhD students that will complete their PhD studies on time. Binary Logistic Regression model is proposed and used on the set of data to determine the number. The results show that only 6.8% of the 2014 PhD students are predicted to graduate on time and the results are compared wih the actual number for validation purpose.

  16. MS PHD'S: A Synergistic Model for Diversifying the Earth Science Community

    Science.gov (United States)

    Ricciardi, L.; Johnson, A.; Williamson Whitney, V.; Ithier-Guzman, W.; Braxton, L.; Johnson, A.

    2013-05-01

    The Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science (MS PHD'S) program focuses on increasing the number of underrepresented minorities (URM) receiving advanced degrees in Earth system sciences (ESS). Subscribing to Aristotle's philosophy that the "whole is greater than the sum of its parts", MS PHD'S uses a synergistic model of tiered mentoring practices, successful minority scientist role models, peer-to-peer community building activities, professional development training techniques, networking opportunities, and state of the art virtual communication tools to facilitate the retention and advancement of underrepresented ESS scientists. Using a three-phase program structure supported by a virtual community, URM students in ESS are afforded opportunities to establish mentoring relationships with successful scientists, build meaningful ties with URM peers and future colleagues, strengthen oral and written communication skills, engage in networking opportunities within premier scientific venues, and maintain continuity of networks formed through program participation. Established in 2003, MS PHD'S is now in its ninth cohort. From the original cohort of 24 participants, the program has grown to support 213 participants. Of these 213 participants, 42 have obtained the doctorate and are employed within the ESS workforce. Another 71 are enrolled in doctoral programs. Looking to the future with the purpose of continually furthering its synergistic philosophy, MS PHD'S has developed a new initiative, Beyond the PhD, designed to support and advance the representation of URM scientists within a global workforce.

  17. Oxygen-dependent ATF-4 stability is mediated by the PHD3 oxygen sensor.

    Science.gov (United States)

    Köditz, Jens; Nesper, Jutta; Wottawa, Marieke; Stiehl, Daniel P; Camenisch, Gieri; Franke, Corinna; Myllyharju, Johanna; Wenger, Roland H; Katschinski, Dörthe M

    2007-11-15

    The activating transcription factor-4 (ATF-4) is translationally induced under anoxic conditions, mediates part of the unfolded protein response following endoplasmic reticulum (ER) stress, and is a critical regulator of cell fate. Here, we identified the zipper II domain of ATF-4 to interact with the oxygen sensor prolyl-4-hydroxylase domain 3 (PHD3). The PHD inhibitors dimethyloxalylglycine (DMOG) and hypoxia, or proteasomal inhibition, all induced ATF-4 protein levels. Hypoxic induction of ATF-4 was due to increased protein stability, but was independent of the ubiquitin ligase von Hippel-Lindau protein (pVHL). A novel oxygen-dependent degradation (ODD) domain was identified adjacent to the zipper II domain. Mutations of 5 prolyl residues within this ODD domain or siRNA-mediated down-regulation of PHD3, but not of PHD2, was sufficient to stabilize ATF-4 under normoxic conditions. These data demonstrate that PHD-dependent oxygen-sensing recruits both the hypoxia-inducible factor (HIF) and ATF-4 systems, and hence not only confers adaptive responses but also cell fate decisions.

  18. Interoperability in digital electrocardiography: harmonization of ISO/IEEE x73-PHD and SCP-ECG.

    Science.gov (United States)

    Trigo, Jesús D; Chiarugi, Franco; Alesanco, Alvaro; Martínez-Espronceda, Miguel; Serrano, Luis; Chronaki, Catherine E; Escayola, Javier; Martínez, Ignacio; García, José

    2010-11-01

    The ISO/IEEE 11073 (x73) family of standards is a reference frame for medical device interoperability. A draft for an ECG device specialization (ISO/IEEE 11073-10406-d02) has already been presented to the Personal Health Device (PHD) Working Group, and the Standard Communications Protocol for Computer-Assisted ElectroCardioGraphy (SCP-ECG) Standard for short-term diagnostic ECGs (EN1064:2005+A1:2007) has recently been approved as part of the x73 family (ISO 11073-91064:2009). These factors suggest the coordinated use of these two standards in foreseeable telecardiology environments, and hence the need to harmonize them. Such harmonization is the subject of this paper. Thus, a mapping of the mandatory attributes defined in the second draft of the ISO/IEEE 11073-10406-d02 and the minimum SCP-ECG fields is presented, and various other capabilities of the SCP-ECG Standard (such as the messaging part) are also analyzed from an x73-PHD point of view. As a result, this paper addresses and analyzes the implications of some inconsistencies in the coordinated use of these two standards. Finally, a proof-of-concept implementation of the draft x73-PHD ECG device specialization is presented, along with the conversion from x73-PHD to SCP-ECG. This paper, therefore, provides recommendations for future implementations of telecardiology systems that are compliant with both x73-PHD and SCP-ECG.

  19. Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2)

    Energy Technology Data Exchange (ETDEWEB)

    McDonough,M.; Li, V.; Flashman, E.; Chowdhury, R.; Mohr, C.; Lienard, B.; Zondlo, J.; Oldham, N.; Clifton, I.; et al.

    2006-01-01

    Cellular and physiological responses to changes in dioxygen levels in metazoans are mediated via the posttranslational oxidation of hypoxia-inducible transcription factor (HIF). Hydroxylation of conserved prolyl residues in the HIF-{alpha} subunit, catalyzed by HIF prolyl-hydroxylases (PHDs), signals for its proteasomal degradation. The requirement of the PHDs for dioxygen links changes in dioxygen levels with the transcriptional regulation of the gene array that enables the cellular response to chronic hypoxia; the PHDs thus act as an oxygen-sensing component of the HIF system, and their inhibition mimics the hypoxic response. We describe crystal structures of the catalytic domain of human PHD2, an important prolyl-4-hydroxylase in the human hypoxic response in normal cells, in complex with Fe(II) and an inhibitor to 1.7 Angstroms resolution. PHD2 crystallizes as a homotrimer and contains a double-stranded {beta}-helix core fold common to the Fe(II) and 2-oxoglutarate-dependant dioxygenase family, the residues of which are well conserved in the three human PHD enzymes (PHD 1-3). The structure provides insights into the hypoxic response, helps to rationalize a clinically observed mutation leading to familial erythrocytosis, and will aid in the design of PHD selective inhibitors for the treatment of anemia and ischemic disease.

  20. GM-PHD Filter Combined with Track-Estimate Association and Numerical Interpolation

    Directory of Open Access Journals (Sweden)

    Jinguang Chen

    2015-01-01

    Full Text Available For the standard Gaussian mixture probability hypothesis density (GM-PHD filter, the number of targets can be overestimated if the clutter rate is too high or underestimated if the detection rate is too low. These problems seriously affect the accuracy of multitarget tracking for the number and the value of measurements and clutters cannot be distinguished and recognized. Therefore, we proposed an improved GM-PHD filter to tackle these problems. Firstly, a track-estimate association was implemented in the filtering process to detect and remove false-alarm targets. Secondly, a numerical interpolation technique was used to compensate the missing targets caused by low detection rate. At the end of this paper, simulation results were presented to demonstrate the proposed GM-PHD algorithm is more effective in estimating the number and state of targets than the previous ones.

  1. Low immediate scientific yield of the PhD among medical doctors

    DEFF Research Database (Denmark)

    Fosbol, Emil L.; Fosbøl, Philip Loldrup; Rerup, Sofie

    2016-01-01

    Background: We studied the scientific yield of the medical PhD program at all Danish Universities.Methods: We undertook a retrospective observational study. Three PhD schools in Denmark were included in order to evaluate the postdoctoral research production over more than 18 years through....... Scientific activity over time was assessed independently of author-rank and inactivity was measured relative to the date of graduation. Factors associated with inactivity were identified using multivariable logistic regression. 88.6 % of the PhD theses were conducted in internal medicine vs. 11.......12 (IQR 0.61-1.99) papers per year. About 2/3 of the graduates became inactive after 1 year and approximately 21 % of the graduates remained active during the whole follow-up. Female gender was associated with inactivity: adjusted odds ratio 1.59 (95 % confidence interval 1.24-2.05).Conclusions...

  2. Science PhD career preferences: levels, changes, and advisor encouragement.

    Directory of Open Access Journals (Sweden)

    Henry Sauermann

    Full Text Available Even though academic research is often viewed as the preferred career path for PhD trained scientists, most U.S. graduates enter careers in industry, government, or "alternative careers." There has been a growing concern that these career patterns reflect fundamental imbalances between the supply of scientists seeking academic positions and the availability of such positions. However, while government statistics provide insights into realized career transitions, there is little systematic data on scientists' career preferences and thus on the degree to which there is a mismatch between observed career paths and scientists' preferences. Moreover, we lack systematic evidence whether career preferences adjust over the course of the PhD training and to what extent advisors exacerbate imbalances by encouraging their students to pursue academic positions. Based on a national survey of PhD students at tier-one U.S. institutions, we provide insights into the career preferences of junior scientists across the life sciences, physics, and chemistry. We also show that the attractiveness of academic careers decreases significantly over the course of the PhD program, despite the fact that advisors strongly encourage academic careers over non-academic careers. Our data provide an empirical basis for common concerns regarding labor market imbalances. Our results also suggest the need for mechanisms that provide PhD applicants with information that allows them to carefully weigh the costs and benefits of pursuing a PhD, as well as for mechanisms that complement the job market advice advisors give to their current students.

  3. Do PhD supervisors play a role in bridging academic cultures?

    DEFF Research Database (Denmark)

    Elliot, Dely; Kobayashi, Sofie

    , we strongly argue that PhD supervisors also have a significant part to play in facilitating successful transition of their PhD students to a new academic culture. Literature in doctoral education recognises the importance of ‘pastoral care’ in the supervisory bond for nurturing students’ overall...... learning, e.g. confidence and capacity-building in preparation for independent research (Cotterall, 2013; Wright, 2003). Pastoral care arguably includes supervisors’ efforts to facilitate the transition to the new learning environment. Yet, more in-depth examination of this aspect of the supervisory...

  4. The oxygen sensor PHD3 limits glycolysis under hypoxia via direct binding to pyruvate kinase

    Institute of Scientific and Technical Information of China (English)

    Nan Chen; Oliver Rinner; Dominika Czernik; Katarzyna J Nytko; Dan Zheng; Daniel P Stiehl; Nicola Zamboni; Matthias Gstaiger; Christian Frei

    2011-01-01

    @@ Dear Editor, Oxygen levels are critical for cellular physiology.Under low oxygen (hypoxia),cells increase glycolysis while limiting mitochondrial oxidative metabolism.Such adaptation is largely mediated by the transcription factors HIF,which accumulate under hypoxia [1,2].Prolyl hydroxylase domain proteins (PHD) function as cellular oxygen sensors and target HIF for subsequent degradation under normoxia [2].The PHD/HIF pathway is conserved in Drosophila,where a single prolyl hydroxylase,Fatiga,has been characterized.We have previously reported that Fatiga regulates cellular growth rates in a HIF-independent manner,yet mechanisms remained elusive [3].

  5. Empirical Essays on the Labor Market Outcomes of PhD Graduates

    DEFF Research Database (Denmark)

    Pedersen, Heidi Skovgaard

    During the past decade, policy makers have accentuated the need for more PhDs to drive innovation and use their research skills to push the technological frontier. The public sector in Denmark has financially supported a doubling of the number of enrolled PhD students based on a strong belief...... that PhDs accelerate growth. A major objective has been to direct more PhDs to the industry to use their skills to monetize knowledge. However, we have limited evidence on how PhDs are absorbed into the labor market, how the market values PhD labor, and how PhDs value the possibility to work...

  6. Top tips for PhD thesis examination: nurse clinicians, researchers and novices.

    Science.gov (United States)

    Cleary, Michelle; Horsfall, Jan; Hunt, Glenn E

    2012-01-01

    Interestingly, there are very few guidelines in the literature to assist novice nurse PhD examiners. In this paper, we aim to provide information to nurses, researchers or early career academics who have little experience in assessing a university thesis. The article provides background information about recent changes in the university sector; overviews some research on experienced examiners views; presents factors that differentiate between high and low quality PhD theses; and outlines some pointers that may be useful when marking at the doctoral level. Copyright © 2011 Elsevier Ltd. All rights reserved.

  7. Education of MSc and PhD Students in Fluid Power and Mechatronics at DTU

    DEFF Research Database (Denmark)

    Conrad, Finn

    1996-01-01

    The paper deals with education of MSc and PhD students in engineering areas fluid power and mechatronics at the Technical Univ of Denmark, DTU, Lyngby. The new education structure and programs for MSc and PhD students adapted to the change and development of technologies. Focus is on two of twenty...... engineering profilies:(1) Engineeing Design and Product Development and (2)Control Engineering which give possibilitie for specialisation in fluid power and mechatronics design and productdevelopment. Synthesis, design and self-learning competency have a high priority taking the importance of training...

  8. The role of PHD2 mutations in the pathogenesis of erythrocytosis

    Directory of Open Access Journals (Sweden)

    Gardie B

    2014-07-01

    of EPO transcription. The α subunits of the hypoxia-inducible transcription factor are hydroxylated by three prolyl hydroxylase domain (PHD enzymes, which belong to the iron and 2-oxoglutarate-dependent oxygenase superfamily. Sequence analysis of the genes encoding the PHDs in patients with erythrocytosis has revealed heterozygous germline mutations only occurring in Egl nine homolog 1 (EGLN1, also known as PHD2, the gene that encodes PHD2. To date, 24 different EGLN1 mutations comprising missense, frameshift, and nonsense mutations have been described. The phenotypes associated with the patients carrying these mutations are fairly homogeneous and typically limited to erythrocytosis with normal to elevated EPO. However, exceptions exist; for example, there is one case with development of concurrent paraganglioma (PHD2-H374R. Analysis of the erythrocytosis-associated PHD2 missense mutations has shown heterogeneous results. Structural studies reveal that mutations can affect different domains of PHD2. Some are close to the hypoxia-inducible transcription factor α/2-oxoglutarate or the iron binding sites for PHD2. In silico studies demonstrate that the mutations do not always affect fully conserved residues. In vitro and in cellulo studies showed varying effects of the mutations, ranging from mild effects to severe loss of function. The exact mechanism of a potential tumor-suppressor role for PHD2 still needs to be elucidated. A knockin mouse model expressing the first reported PHD2-P317R mutation recapitulates the phenotype observed in humans (erythrocytosis with inappropriately normal serum EPO levels and demonstrates that haploinsufficiency and partial deregulation of PHD2 is sufficient to cause erythrocytosis. Keywords: PHD2, EGLN1, HIF, hypoxia, erythropoietin, erythrocytosis

  9. Experimental study for Yuen-Kim protocol of quantum key distribution with unconditional secure Bell's Theorem Without Inequalities for two Maximally Entangled Particles

    CERN Document Server

    Hirota, O; Sohma, M; Li Ming Wei; Tang, Z L; Liao, C C

    2002-01-01

    In this report, we simulate practical feature of Yuen-Kim protocol for quantum key distribution with unconditional secure. In order to demonstrate them experimentally by intensity modulation/direct detection(IMDD) optical fiber communication system, we use simplified encoding scheme to guarantee security for key information(1 or 0). That is, pairwise M-ary intensity modulation scheme is employed. Furthermore, we give an experimental implementation of YK protocol based on IMDD. A proof of Bell's theorem without inequalities for two maximally entangled particles is proposed using the technique of quantum teleportation. It follows Hardy's arguments for a non-maximally entangled state with the help of two auxiliary particles without correlation. The present proof can be tested by measurements with 100% probability.

  10. The Benefits of Publishing Systematic Quantitative Literature Reviews for PhD Candidates and Other Early-Career Researchers

    Science.gov (United States)

    Pickering, Catherine; Byrne, Jason

    2014-01-01

    Universities increasingly expect students to publish during a PhD candidature because it benefits the candidate, supervisor, institution, and wider community. Here, we describe a method successfully used by early-career researchers including PhD candidates to undertake and publish literature reviews--a challenge for researchers new to a field. Our…

  11. PhD Crisis Discourse: A Critical Approach to the Framing of the Problem and Some Australian "Solutions"

    Science.gov (United States)

    Cuthbert, Denise; Molla, Tebeje

    2015-01-01

    A feature of HE reform discourse is the tendency to construct the rationale for reform in terms of averting calamity and risk. We refer to this risk talk as "crisis discourse." This study examines the formulation of PhD crisis discourse internationally and in Australia. We find that a key feature of PhD crisis discourse is that…

  12. Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Regulates Chondrocyte Differentiation and Secondary Ossification in Mice

    Science.gov (United States)

    Cheng, Shaohong; Aghajanian, Patrick; Pourteymoor, Sheila; Alarcon, Catrina; Mohan, Subburaman

    2016-01-01

    Endochondral ossification plays an important role in the formation of the primary ossification centers (POCs) and secondary ossification centers (SOCs) of mammalian long bones. However, the molecular mechanisms that regulate POC and SOC formation are different. We recently demonstrated that Prolyl Hydroxylase Domain-containing Protein 2 (Phd2) is a key mediator of vitamin C effects on bone. We investigated the role of Phd2 on endochondral ossification of the epiphyses by conditionally deleting the Phd2 gene in osteoblasts and chondrocytes. We found that the deletion of Phd2 in osteoblasts did not cause changes in bone parameters in the proximal tibial epiphyses in 5 week old mice. In contrast, deletion of Phd2 in chondrocytes resulted in increased bone mass and bone formation rate (normalized to tissue volume) in long bone epiphyses, indicating that Phd2 expressed in chondrocytes, but not osteoblasts, negatively regulates secondary ossification of epiphyses. Phd2 deletion in chondrocytes elevated mRNA expression of hypoxia-inducible factor (HIF) signaling molecules including Hif-1α, Hif-2α, Vegfa, Vegfb, and Epo, as well as markers for chondrocyte hypertrophy and mineralization such as Col10, osterix, alkaline phosphatase, and bone sialoprotein. These data suggest that Phd2 expressed in chondrocytes inhibits endochondral ossification at the epiphysis by suppressing HIF signaling pathways. PMID:27775044

  13. A Networked Pathway to the PhD: The African-Norwegian Case of Productive Learning Cultures

    Science.gov (United States)

    Hattingh, Annemarie; Lillejord, Solvi

    2011-01-01

    How do PhD students become socialised into the professional world of academic work? This article pays attention to a "networked" support pathway towards a PhD. The network constitutes an international research collaboration through a programme called Productive Learning Cultures (PLC) (2002-2011) between Norway and seven countries,…

  14. Effects of PhD examination stress on allopregnanolone and cortisol plasma levels and peripheral benzodiazepine receptor density.

    NARCIS (Netherlands)

    Droogleever Fortuyn, H.A.; Broekhoven, F. van; Span, P.N.; Backstrom, T.; Zitman, F.G.; Verkes, R.J.

    2004-01-01

    Peripheral benzodiazepine receptor (PBR) density in blood platelets and plasma allopregnanolone concentration in humans were determined following acute stress as represented by PhD examination. Fifteen healthy PhD students participated. Heart rate, blood pressure, plasma allopregnanolone, plasma cor

  15. Publishing and Learning Writing for Publication in English: Perspectives of NNES PhD Students in Science

    Science.gov (United States)

    Huang, Ju Chuan

    2010-01-01

    Publication in international journals has become a prerequisite to PhD graduation. This study thus provides a framework for understanding the learning of writing skills and publishing practices of nonnative English-speaking PhD students by investigating their perceptions of publishing and learning to write for publication. Findings show that these…

  16. Changes of urinary L-FABP, KIM-1, NGAL and serum cystatin C in diabetic nephropathy and its clinical value%尿L-FABP、KIM-1、NGAL和血清cystatin C在糖尿病肾病中的变化及意义

    Institute of Scientific and Technical Information of China (English)

    梁雅灵; 杨茂君; 李衍辉; 黎秋晗; 黄炜; 徐勇

    2016-01-01

    Objective To investigate the changes of urinary liver-type fatty acid binding protein (L-FABP),kidney injury molecule-1 (KIM-1),neutrophil gelatinase-associated lipocalin (NGAL) and serum cystatin C in diabetic nephropathy and its clinical value.Methods A total of 118 patients diagnosed with type 2 diabetes in the Department of Endocrinology of Affiliated Hospital of Sichuan Medical University from October 2011 to October 2012 were recruited in this study.According to their urinary albumin-to-creatinine ratio(UACR),patients were divided into normal albuminuria group(n =45),microalbuminuria group (n =42),and macroalbuminuria group (n =43).A total of 41 healthy subjects were enrolled as normal control group(n =41).Enzyme-linked immunosorbent assays were used to measure the levels of urinary L-FABP,KIM-1 and NGAL.Turbidimetric inhibition immuno-assay was used to measure the expression of serum cystatin C.All the urinary indicators were adjusted by the level of urine creatinine.Changes of biomarkers in each group and their crrelations between UACR,eGFR were also compared.Results Compared with normal control group,urinary L-FABP and serum cystatin C were significantly increased in diabetic groups (x2 =77.959,104.003,all P < 0.05);urinary KIM-1 was also significantly increased (x2 =29.711,P < 0.05).Urinary NGAL was increased in microalbuminuria group and macroalbuminuria group compared with normal control group and normal albuminuria group(x2 =23.833,P < 0.05),but there were no significant difference between normal albuminuria group and normal control group.Urinary L-FABP,KIM-1,NGAL and serum cystatin C were positively correlated with UACR (r =0.719,0.427,0.327,0.726,all P < 0.01);while L-FABP and serum cystatin C were negatively correlated with eGFR (r =-0.301,-0.791,all P < 0.01).Conclusion Urinary L-FABP,KIM-1,NGAL and serum cystatin C are increased in early diabetic nephropathy,while urinary L-FABP and serum cystatin C may be the better biomarkers to

  17. The prevalence of musculoskeletal disorders and occupational risk factors in Kashan SAIPA automobile industry workers by key indicator method (KIM, 1390

    Directory of Open Access Journals (Sweden)

    2012-05-01

    Full Text Available Introduction: work related musculoskeletal disorders are the most wide spread type of occupational diseases among workers. Awkward body postures during work and manual material handling are among the most important risk factors of musculoskeletal disorders in different jobs. Due to importance of recognizing these factors prevalence and risk factor of work related musculoskeletal disorders, this research was aimed to study the among employees of Kashan City’s Saipa automobile industry in 2011. .Material and Method: This study is a descriptive-cross sectional study conducted among workers with manual material handling 37 activities and 84 work duties. To recognize musculoskeletal disorders, body map questionnaire was applied and occupational risk factors were evaluated using Key Index Method (KIM. Data was analyzed using SPSS and Excel software. .Result: Highest prevalence of musculoskeletal disorders was in low and upper back region (%92. Based on the results from KIM, workers in the installing the tire, shuttle-aided fitting of seat, and engine work station had higher risk level with the scores of 66, 52 and 52, respectively. Risk level among three individuals (%3.6 was at 1, 40 (%47.6 at 2, 38 (%45.2 risk level 3, and 3 (%3.6 at 4. .Conclusion: Awkward body posture, improper twisting and flexion of low back were major risk factor among worker doing manual material handling tasks. Regarding the high prevalence of musculoskeletal disorders, appropriate ergonomic interventions such as engineering and organization interactions can reduce this risk factors (posture, heavy load, duration, workplace conditions as much as the risk level reach to an acceptable level.

  18. THE ENTROPY OF A KIM BLACK HOLE AND THE NERNST THEOREM%Kim黑洞熵与能斯特定理

    Institute of Scientific and Technical Information of China (English)

    赵仁; 张丽春

    2001-01-01

    We start with Klein-Gordon equation on the background of the Kim black hole and calculate the free energy and entropy of a scalar field by the brick-wall method. It is shown that the entropy is not only related to the area of an outer horizon but also is a function of inner horizon's area. Taking some appr oximation, we can obtain that the entropy only is proportional to the area of an outer horizon. Further more, the entropy expressed by location parameter of the outer and inner horizon approaches zero, when the radiation temperature of a black hole approaches zero. This satisfies the Nernst theorem. It can be taken as Planck absolute entropy of a black hole.%从Kim 时空背景下的 Klein-Gordon 方程出发,利用 brick-wall 方法计算标量场的自由能和熵.得到标量场的熵不仅与黑洞的外视界面积有关,而且也是内视界面积的函数.所得结论,当取某种近似时,可得到熵只与外视界面积成正比的关系.并且表明,用内外视界位置参量表达的熵,在黑洞辐射温度趋于绝对零度时,黑洞的熵也趋于零,它满足能斯特定理,可视为黑洞的普朗克绝对熵.

  19. Transcriptional analysis of kidneys during repair from AKI reveals possible roles for NGAL and KIM-1 as biomarkers of AKI-to-CKD transition.

    Science.gov (United States)

    Ko, Gang Jee; Grigoryev, Dmitry N; Linfert, Douglas; Jang, Hye Ryoun; Watkins, Tonya; Cheadle, Chris; Racusen, Lorraine; Rabb, Hamid

    2010-06-01

    Acute kidney injury (AKI) is being increasingly shown to be a risk factor for chronic kidney disease (CKD), but little is known about the possible mechanistic links. We hypothesized that analysis of the genomic signature in the repair stage after AKI would reveal pathways that could link AKI and CKD. Unilateral renal pedicle clamping for 45 min was performed in male C57BL/6J mice. Mice were euthanized at 3, 10, and 28 days after ischemia-reperfusion injury (IRI). Total RNA was isolated from kidney and analyzed using an Illumina mouse array. Among 24,600 tested genes, 242, 146, and 46 genes were upregulated at days 3, 10, and 28 after IRI, and 85, 35, and 0 genes were downregulated, respectively. Gene ontology analysis showed that gene expression changes were primarily related to immune and inflammatory pathways both early and late after AKI. The most highly upregulated genes late after AKI were hepatitis A virus cellular receptor 1 (Havcr1) and lipocalin 2 (Lcn2), which code for kidney injury molecule-1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL), respectively. This was unexpected since they are both primarily potential biomarkers of the early stage of AKI. Furthermore, increases observed in gene expression in amiloride binding protein 1, vascular cell adhesion molecule-1, and endothelin 1 could explain the salt-sensitive hypertension that can follow AKI. These data suggested that 1) persistent inflammation and immune responses late after AKI could contribute to the pathogenesis of CKD, 2) late upregulation of KIM-1 and NGAL could be a useful marker for sustained renal injury after AKI, and 3) hypertension-related gene changes could underlie mechanisms for persistent renal and vascular injury after AKI.

  20. Factors Affecting Timely Completion of a PhD: A Complex Systems Approach

    Science.gov (United States)

    Pitchforth, Jegar; Beames, Stephanie; Thomas, Aleysha; Falk, Matthew; Farr, Charisse; Gasson, Susan; Thamrin, Sri Astuti; Mengersen, Kerrie

    2012-01-01

    Completing a PhD on time is a complex process, influenced by many interacting factors. In this paper we take a Bayesian Network approach to analyzing the factors perceived to be important in achieving this aim. Focusing on a single research group in Mathematical Sciences, we develop a conceptual model to describe the factors considered to be…

  1. Factors Influencing International PhD Students to Study Physics in Australia

    Science.gov (United States)

    Choi, Serene H.-J.; Nieminen, Timo A.; Townson, Peter

    2012-01-01

    Since physics research is an activity of an active international community, international visits are a common way for physicists to share scientific knowledge and skills. International mobility of physicists is also important for PhD physics study and research training. We investigated personal and social factors that influenced the decision for…

  2. International Students' Motivation to Pursue and Complete a Ph.D. in the U.S.

    Science.gov (United States)

    Zhou, Ji

    2015-01-01

    This study explores what motivates 19 international students to pursue a Ph.D. at a public research university in the U.S. and, more importantly, what motivates them to persist despite unsatisfying socialization. Based on value-expectancy achievement motivation theory, four motivations emerged: intrinsic interest in research, intrinsic interest in…

  3. Constructing an Institutional Identity in University Tea Rooms: The International PhD Student Experience

    Science.gov (United States)

    Fotovatian, Sepideh; Miller, Jenny

    2014-01-01

    This case study profiles eight international PhD students and describes the process of the construction and negotiation of their social and institutional identities in an Australian university. Audio-recorded informal conversations of the students highlight the role of social membership, staffroom interactions and language in the construction of…

  4. Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis.

    Science.gov (United States)

    Madsen, Chris D; Pedersen, Jesper T; Venning, Freja A; Singh, Lukram Babloo; Moeendarbary, Emad; Charras, Guillaume; Cox, Thomas R; Sahai, Erik; Erler, Janine T

    2015-10-01

    Cancer-associated fibroblasts (CAFs) interact with tumour cells and promote growth and metastasis. Here, we show that CAF activation is reversible: chronic hypoxia deactivates CAFs, resulting in the loss of contractile force, reduced remodelling of the surrounding extracellular matrix and, ultimately, impaired CAF-mediated cancer cell invasion. Hypoxia inhibits prolyl hydroxylase domain protein 2 (PHD2), leading to hypoxia-inducible factor (HIF)-1α stabilisation, reduced expression of αSMA and periostin, and reduced myosin II activity. Loss of PHD2 in CAFs phenocopies the effects of hypoxia, which can be prevented by simultaneous depletion of HIF-1α. Treatment with the PHD inhibitor DMOG in an orthotopic breast cancer model significantly decreases spontaneous metastases to the lungs and liver, associated with decreased tumour stiffness and fibroblast activation. PHD2 depletion in CAFs co-injected with tumour cells similarly prevents CAF-induced metastasis to lungs and liver. Our data argue that reversion of CAFs towards a less active state is possible and could have important clinical implications.

  5. Career Aspirations and Career Outcomes for Solar and Space Physics Ph.D

    Science.gov (United States)

    Moldwin, M.; Morrow, C. A.

    2013-12-01

    Results from a recent graduate student survey found unsurprisingly that Solar and Space Physics (S&SP) Ph.D. graduate students almost all aspire to have research careers in Solar and Space Physics. This study reports on the research career outcomes over the last decade for S&SP Ph.Ds. We used publication of peer-reviewed articles as the indicator for persistence in a research career. We found that nearly two-thirds (64%) of Ph.D.s who graduated between 2001 to 2009 published refereed-papers four or more years after their Ph.D., while 17% of Ph.D.s never published another paper beyond the year they received their Ph.D. The remaining 19% of Ph.Ds, stopped publishing within three-years of receiving their Ph.D. We found that though there is statistically no difference on persistence of publishing research between graduates of the largest programs compared to all other programs, there are significant differences between programs. We also found there was no gender differences in any of the persistence data (i.e., men and women stop or continue publishing at the same rates). Graduate programs, faculty advisors and potential graduate students can use these data for career planning. This study suggests that a significant majority of S&SP Ph.D.s (77%) find post-doctoral research positions and a majority (56%) find research careers beyond their post-doc.

  6. Competitive binding of a benzimidazole to the histone-binding pocket of the Pygo PHD finger.

    Science.gov (United States)

    Miller, Thomas C R; Rutherford, Trevor J; Birchall, Kristian; Chugh, Jasveen; Fiedler, Marc; Bienz, Mariann

    2014-12-19

    The Pygo-BCL9 complex is a chromatin reader, facilitating β-catenin-mediated oncogenesis, and is thus emerging as a potential therapeutic target for cancer. Its function relies on two ligand-binding surfaces of Pygo's PHD finger that anchor the histone H3 tail methylated at lysine 4 (H3K4me) with assistance from the BCL9 HD1 domain. Here, we report the first use of fragment-based screening by NMR to identify small molecules that block protein-protein interactions by a PHD finger. This led to the discovery of a set of benzothiazoles that bind to a cleft emanating from the PHD-HD1 interface, as defined by X-ray crystallography. Furthermore, we discovered a benzimidazole that docks into the H3K4me specificity pocket and displaces the native H3K4me peptide from the PHD finger. Our study demonstrates the ligandability of the Pygo-BCL9 complex and uncovers a privileged scaffold as a template for future development of lead inhibitors of oncogenesis.

  7. Three new students selected for the ATLAS PhD Grant Scheme

    CERN Multimedia

    Antonella Del Rosso

    2016-01-01

    Initiated in 2013, the ATLAS PhD Grant Scheme aims to enable young, talented and motivated students to work on part of their PhD thesis at CERN. The collaboration has just selected the three students who will start their theses in 2016.   The three students who received the ATLAS grant, which will cover part of their PhD studies. From left to right: Ruth Jacobs (Germany), Artem Basalaev (Russia), Nedaa B I Asbah (Palestine). The ATLAS PhD Grant Scheme was made possible thanks to a large donation by former ATLAS spokespersons Fabiola Gianotti and Peter Jenni, who started the fund with money from the Fundamental Physics Prize they received in 2013. Applications are handled by CERN HR, via this link. The aim of the initiative is to offer a unique educational opportunity to students within the ATLAS collaboration and to give them the possibility to continue their career in particle physics. Selected candidates receive a stipend allowing them to spend one year at CERN, followed by one year at their h...

  8. PhD and the Manager's Dream: Professionalising the Students, the Degree and the Supervisors?

    Science.gov (United States)

    Matos, Frederico

    2013-01-01

    This article has two main aims: to analyse relevant literature on the doctoral degree, and to assess whether recent funding changes in the UK have changed the nature of the PhD in the social sciences in a research-intensive and prestigious UK university. Data were collected at BlueSkies University where interviews with social sciences PhD…

  9. Ph.D. Thesis: Quantum Field Theory and Gravity in Causal Sets

    CERN Document Server

    Sverdlov, Roman

    2009-01-01

    This is is a copy of dissertation that I have submitted in defense of my ph.d. thesis, with some minor changes that I have made since then. The goal of the project is to generalize matter fields and their Lagrangians from regular space time to causal sets.

  10. Ph.D. Thesis: Quantum Field Theory and Gravity in Causal Sets

    Science.gov (United States)

    Sverdlov, Roman

    2009-05-01

    This is is a copy of dissertation that I have submitted in defense of my ph.d. thesis, with some minor changes that I have made since then. The goal of the project is to generalize matter fields and their Lagrangians from regular space time to causal sets.

  11. Winning the PhD Game: Evocative Playing of Snakes and Ladders

    Science.gov (United States)

    Dickie, Carolyn

    2011-01-01

    The purpose of this paper is to describe a qualitative approach to developing an understanding of the lived experiences of PhD students. Rather than relying on textbook reports and theories about studying a higher degree by research, by allowing the students' voices to be heard, explicit and conscious research can be used to generate appropriate…

  12. The New Debate: The PhD versus the MFA Degree.

    Science.gov (United States)

    Barranger, Milly S.; And Others

    1986-01-01

    Introduces and includes "The Ritz Bar or ABD: In Defense of the MFA," in which Peter Garvie defends the professionalism of the MFA degree in theatre, and "The PhD in Theatre--A Vanishing Degree?" Richard Hornby's discussion of the importance of the doctoral degree as the standard teaching degree. (PD)

  13. At the MLA, a Ph.D. Candidate Navigates the Jobs Gantlet

    Science.gov (United States)

    Patton, Stacey

    2012-01-01

    It's the night before one of Javier Jimenez's big job interviews at the Modern Language Association (MLA) meeting. The 35-year-old graduate student, who is scheduled to earn his Ph.D. in comparative literature this spring from the University of California at Berkeley, is trying to ward off anxiety and abdominal pains. The mystique of the MLA, the…

  14. The Future of Rhetoric in English Department Ph.D. Programs.

    Science.gov (United States)

    Clark, Suzanne

    1995-01-01

    Offers a utopian vision of what the place of rhetoric should be in a department that thinks of itself as literary. Argues that a Ph.D. in English that encompasses both literature and rhetoric works because it is really a degree in rhetoric. (TB)

  15. Career-Self Management and Entrepreneurship: An Experience with PhD Students

    Science.gov (United States)

    Pinto, Joana Carneiro; do Ceu Taveira, Maria; Sa, Elisabete

    2012-01-01

    Introduction: This study presents an experience developed with PhD students aimed to analyze the extent to which career self-management should be approached along with entrepreneurship issues to promote students' career development. Method: An intervention group who attended a Career Self-Management Seminar (EG1), a comparison group who attended…

  16. From Student to Scholar: The Academic Library and Social Sciences PhD Students' Transformation

    Science.gov (United States)

    Fleming-May, Rachel; Yuro, Lisa

    2009-01-01

    Although research concerning the information-seeking behavior of academic library users is abundant, few studies have focused specifically on PhD students. This oversight has had an impact on librarians' ability to effectively market services such as information literacy instruction and research assistance to doctoral students. In order to…

  17. Regulating Emotions and Aiming for a Ph.D.: Excerpts from "Anthropology Matters"

    Science.gov (United States)

    Hovland, Ingie

    2012-01-01

    In this article I will present a range of experiences of graduate socialisation that have been discussed in past articles in the journal "Anthropology Matters". These are the experiences of social anthropology Ph.D. students in the United Kingdom. The overarching theme for the article is "regulating emotions", and the excerpts…

  18. PhD versus DSW: A Critique of Trends in Social Work Doctoral Education

    Science.gov (United States)

    Howard, Tyriesa

    2016-01-01

    Social work educators are in a phase of reintroducing the doctor of social work (DSW) degree and refining distinctions between PhD and DSW doctoral programs. This article examines how the two options have been prey to a noticeable "seesaw of precedence", resulting in a debatable history of social work's approach to doctoral education…

  19. Temporary contracts : Effect on job satisfaction and personal lives of recent PhD graduates

    NARCIS (Netherlands)

    Waaijer, C.J.F.; Belder, R.; Sonneveld, H.; Van, Bochove C.A.; Van, der Weijden I.C.M.

    2017-01-01

    In this study, we assess the effects of temporary employment on job satisfaction and the personal lives of recent PhD graduates. Temporary employment is becoming increasingly prevalent in many sectors, but has been relatively common in academia, especially for early career scientists. Labor market

  20. Regulating Emotions and Aiming for a Ph.D.: Excerpts from "Anthropology Matters"

    Science.gov (United States)

    Hovland, Ingie

    2012-01-01

    In this article I will present a range of experiences of graduate socialisation that have been discussed in past articles in the journal "Anthropology Matters". These are the experiences of social anthropology Ph.D. students in the United Kingdom. The overarching theme for the article is "regulating emotions", and the excerpts…

  1. The Impact of Publishing during PhD Studies on Career Research Publication, Visibility, and Collaborations

    Science.gov (United States)

    Horta, Hugo; Santos, João M.

    2016-01-01

    This study analyzes the impact that publishing during the period of PhD study has on researchers' future knowledge production, impact, and co-authorship. The analysis is based on a representative sample of PhDs from all fields of science working in Portugal. For each researcher in the dataset, we compiled a lifetime publication record and…

  2. A model perception on the independence of PhD students in ...

    African Journals Online (AJOL)

    Amy Stambach

    It is familiar that PhD students from University of Rwanda (UR) are used to ... from the beginning of doctoral studies until the successful completion by .... completion of a research degree and one shall have taken an approved and certified course on ... In addition to the supervisors, an adviser or advisers may be proposed to ...

  3. The Focus and Substance of Formative Comment Provided by PhD Examiners

    Science.gov (United States)

    Holbrook, Allyson; Bourke, Sid; Fairbairn, Hedy; Lovat, Terence

    2014-01-01

    In practice and process PhD examination is distinctive, reflecting the high expectations of students whose learning has been directed to their becoming researchers. This article builds on previous research on the examination of Australian theses that revealed that examiners in Science (n?=?542) and Education (n?=?241) provide a substantial…

  4. International Students' Motivation to Pursue and Complete a Ph.D. in the U.S.

    Science.gov (United States)

    Zhou, Ji

    2015-01-01

    This study explores what motivates 19 international students to pursue a Ph.D. at a public research university in the U.S. and, more importantly, what motivates them to persist despite unsatisfying socialization. Based on value-expectancy achievement motivation theory, four motivations emerged: intrinsic interest in research, intrinsic interest in…

  5. Completing a PhD by Publication: A Review of Australian Policy and Implications for Practice

    Science.gov (United States)

    Jackson, Denise

    2013-01-01

    There is increasing impetus for higher-degree-by-research students to publish during candidature. Research performance, including higher degree completions and publication output, commonly determines university funding, and doctorates with publishing experience are better positioned for a career in softening academic labour markets. The PhD by…

  6. Regulating Emotions and Aiming for a Ph.D.: Excerpts from "Anthropology Matters"

    Science.gov (United States)

    Hovland, Ingie

    2012-01-01

    In this article I will present a range of experiences of graduate socialisation that have been discussed in past articles in the journal "Anthropology Matters". These are the experiences of social anthropology Ph.D. students in the United Kingdom. The overarching theme for the article is "regulating emotions", and the excerpts presented illustrate…

  7. COMPARISON OF HEDGES IN M.A. THESES AND PH.D. DISSERTATIONS IN ELT

    Directory of Open Access Journals (Sweden)

    Çağla ATMACA

    2016-08-01

    Full Text Available Writers use some textual devices like hedges and boosters in order to contribute to their textual voice. Differences between M.A. theses and Ph.D. dissertations in English Language Teaching (ELT Department in terms of hedges in Turkish context seem to be an overlooked area. Thus, this paper aims to find the similarities and differences between M.A. theses and Ph.D. dissertations about English Language Teaching in terms of hedges. For this purpose, 10 M.A. theses and 10 Ph.D. dissertations were randomly chosen. Data were analyzed and categorized on the basis of contextual features with the help of content analysis. Various hedging tools emerged as a result of content analysis and it was found that hedges used in the Ph.D. dissertations nearly double those in the M.A. theses. Moreover, modals -followed by passivization- are the leading form of hedging while nouns have the least frequency of hedging type, which could explain some of the differences between novice and experienced writers. In the light of these findings, important implications are drawn for graduate and postgraduate students to enhance their writing skills and be familiar with the principles of academic writing for their future career.

  8. Ability, academic climate, and going abroad for work or pursuing a PhD

    NARCIS (Netherlands)

    Bertrand-Cloodt, D.A.M.; Cörvers, F.; Heijke, J.A.M.

    2014-01-01

    We investigate whether a creaming off of highly able students from Dutch universities is taking place. Therefore, we examine the relation between ability and the destination of recent graduates of Dutch universities. Students can choose to continue their academic career by investing in a PhD degree

  9. Ability, academic climate, and going abroad for work or pursuing a PhD

    NARCIS (Netherlands)

    Bertrand - Cloodt, Danielle; Cörvers, Frank; Heijke, Hans

    We investigate whether highly able students are being creamed off from Dutch universities. Therefore, we examine the relation between ability and the destination of recent graduates of Dutch universities. Students can choose to continue their academic career by investing in a PhD degree instead of

  10. Learning Opportunities in PhD Supervisory Talks: A Social Constructionist Perspective

    Science.gov (United States)

    Tian, Wenwen; Singhasiri, Wareesiri

    2016-01-01

    Although PhD supervision has been recognised as an educative process and a complex pedagogy for decades, there is little research into on-site pedagogic processes. Informed by social constructionism and a Foucauldian approach, this qualitative case study explores how learning opportunities were created by analysing both a supervisor's verbal…

  11. Ensuring PhD development of responsible conduct of research behaviors: who's responsible?

    Science.gov (United States)

    Titus, Sandra L; Ballou, Janice M

    2014-03-01

    The importance of public confidence in scientific findings and trust in scientists cannot be overstated. Thus, it becomes critical for the scientific community to focus on enhancing the strategies used to educate future scientists on ethical research behaviors. What we are lacking is knowledge on how faculty members shape and develop ethical research standards with their students. We are presenting the results of a survey with 3,500 research faculty members. We believe this is the first report on how faculty work with and educate their PhD students on basic research standards. Specifically, we wanted to determine whether individual faculty members, who are advisors or mentors, differ in how they implemented components of responsible conduct of research (RCR) with their PhD students. Mentors were more likely than advisors or supervisors to report working with all of their PhDs, who graduated in the last 5 years, on the 17 recognized critical components of RCR training and research skill development. We also found about half of the faculty members believe RCR is an institutional responsibility versus a faculty responsibility. Less than a quarter have had opportunities to participate in faculty training to be a better mentor, advisor, or research teacher, and about one third of faculty did not or could not remember whether they had guidelines related to their responsibilities to PhD students. We discuss the implications of our findings and focus on ways that PhD research mentoring can be enhanced.

  12. Ability, academic climate, and going abroad for work or pursuing a PhD

    NARCIS (Netherlands)

    Bertrand-Cloodt, D.A.M.; Cörvers, F.; Heijke, J.A.M.

    2014-01-01

    We investigate whether a creaming off of highly able students from Dutch universities is taking place. Therefore, we examine the relation between ability and the destination of recent graduates of Dutch universities. Students can choose to continue their academic career by investing in a PhD degree

  13. The first recipients of the ATLAS PhD Grant Scholarship Programme 2014

    CERN Multimedia

    Marcelloni, Claudia

    2014-01-01

    First recipients of the ATLAS PhD Grant Scholarship 2014 : With certificates, Lailin Xu, Josefina Alconada, and Gagik Vardanyan. The selection committee members, IFAE Barcelona’s Martine Bosman, Fabiola Gianotti, Peter Jenni and from CERN HR James PurvisProgramme: Lailin Xu, Josefina Alconada, and Gagik Vardanyan

  14. "The Day All of the Different Parts of Me Can Come Along": Intersectionality and U.S. Third World Feminism in the Poetry of Pat Parker and Willyce Kim.

    Science.gov (United States)

    Van Ausdall, Mimi Iimuro

    2015-01-01

    This article brings to light the poetry of Pat Parker and Willyce Kim, two key figures within the 1970s and '80s women in print movement. While Parker and Kim have been rightly placed within African-American and Asian-American histories, respectively, and working-class and lesbian-feminist literary histories, their work is most fully understood within the context of U.S. Third World Feminism. Through close readings of poetic form and content in addition to engagement with current debates about intersectionality as a methodology, the article links Kim and Parker's works to central contributions of U.S. Third World Feminism such as intersectionality and power across and within difference that continue to influence feminist theory today.

  15. Exploring challenges of the reproductive health PhD curriculum: A qualitative research

    Directory of Open Access Journals (Sweden)

    Sh Kohan

    2016-07-01

    Full Text Available Introduction: Enhancing the quality and dynamicity of higher education programs requires continuous evaluation of curriculums. Reproductive health PhD program was established in 2006 in Iran while recommending that its curriculum be evaluated by assessing graduates’ performance in workplace and surveying students, faculty members and managers. This study aimed to explore challenges of the curriculum of reproductive health PhD program. Methods: Employing a qualitative content analysis approach and using purposive and sometimes opportunistic sampling, experiences and viewpoints of 33 graduates and students of reproductive health PhD program, educational managers and reproductive health board members about the curriculum of reproductive health PhD program were collected through individual interviews and notes in 2014-15. Data were transcribed and important expressions were coded. Classification of similar codes led to preliminary categories. Five main categories were extracted by further classifications. Results: The five main categories included inadequacy of course topics and contents, challenges of student education, failure in realizing curriculum goals, long research period, and ambiguity in graduates’ professional status were appeared; each of these included various subcategories. Conclusion: Results showed that the curriculum of reproductive health PhD program required revisions to meet the program’s mission and designing courses such as sexual health and reinforcing the clinical nature of the program were necessary. Moreover, the results emphasized that the establishment of an independent educational department of reproductive health for managing higher education affairs and greater supervision of the reproductive health board on educational affairs was necessary. Furthermore, reproductive health specialists should be employed in different positions to meet society’s reproductive health needs.

  16. [Research misconduct: Knowledge, actions and attitudes of PhD candidates].

    Science.gov (United States)

    Hofmann, Bjørn; Holm, Søren

    2016-09-01

    BACKGROUND Increasing attention is being paid to research misconduct in academic journals and in the media, but we know relatively little about its extent or attitudes to research misconduct, or how these are changing. This study therefore aims to investigate PhD candidates' knowledge, own actions and attitudes to specific forms of research misconduct.MATERIAL AND METHOD In autumn 2015, an anonymous questionnaire survey was distributed to all participants in the introductory course for PhD candidates at the Faculty of Medicine at the University of Oslo.RESULTS Altogether 77 PhD candidates (79 %) responded to the questionnaire. A total of 62 % conducted clinical research and 25 % conducted basic research. Around one in four had heard about serious forms of research misconduct in the previous year, and around 4 % were aware of various forms of serious research misconduct in their own department in the previous year. Compared to earlier studies, an increasing number (16 %) responded that they had been subjected to unethical pressure with regard to inclusion or order of authors. Approximately two-thirds were uncertain of whether their department had written policies for academic conduct. One-third of PhD candidates did not disassociate themselves from actions that are generally viewed as scientific misconduct. One-tenth thought it acceptable to falsify or fabricate data in order to expedite publication, one-fifth did not object to taking the credit for others' ideas, and almost half did not believe it was wrong to attempt a number of methods of analysis until one arrived at a significant answer.INTERPRETATION PhD candidates at the Faculty of Medicine were aware of research misconduct, both generally and from their own department. They themselves reported some type of scientific misconduct, and a large majority were uncertain of their department's guidelines. Some of the candidates also accepted several forms of research misconduct.

  17. Skill development in collaborative research projects: A comparison between PhD students in multi-actor research programs and in traditional trajectories

    OpenAIRE

    Wardenaar, T.; Belder, R.; de Goede, M.E.E; Horlings, E.; van den Besselaar, P.

    2014-01-01

    The growing number of PhD students has spurred debates about the societal relevance of PhD training trajectories. The academic labour market does not provide enough jobs and many PhD graduates will have a career outside academia. It has been questioned whether current PhD training trajectories are still adequate and collaborative research projects are introduced as alternative trajectories. Such trajectories can support the development of a broader set of skills, but might have adverse effect...

  18. 尿NGAL、KIM-1、L-FABP水平在脓毒症急性肾损伤早期诊断中的临床意义

    Institute of Scientific and Technical Information of China (English)

    许建宁; 徐玉辉; 蓝海兵

    2015-01-01

    目的 探讨尿NGAL、KIM-1、L-FABP水平在脓毒症急性肾损伤(AKI)早期诊断中的临床意义.方法 前瞻性的收集综合ICU的脓毒症患者91例,其中38例合并AKI,通过检测患者尿NGAL、KIM-1、L-FABP水平及血肌酐及尿素氨水平变化,对尿NGAL、KIM-1、L-FABP水平与血肌酐及尿素氮进行相关性分析,通过绘制受试者工作特征曲线(ROC),计算尿NGAL、KIM-1、L-FABP水平在早期诊断脓毒症合并AKI中的敏感性及特异性.结果 观察组患者与对照组相比,尿NGAL、L-FABP水平在诊断前48 h即出现显著升高(P<0.05),尿KIM-1水平在在诊断前24 h即出现显著升高(P<0.05);尿NGAL、KIM-1、L-FABP水平与血肌酐、尿素氮呈正相关性;ROC曲线分析发现,诊断前24h,尿NGAL、L-FABP水平在诊断脓毒症合并AKI时具有较高的敏感性及特异性,诊断前0h,尿KIM-1水平在诊断脓毒症合并AKI时具有较高的敏感性及特异性.结论 尿NGAL、KIM-1、L-FABP水平均在脓毒症早期出现显著升高,可以作为脓毒症AKI早期诊断的指标.

  19. Does working with industry come at a price? A study of doctoral candidates’ performance in collaborative vs. non-collaborative Ph.D. projects

    NARCIS (Netherlands)

    Salimi, Negin; Bekkers, Rudi; Frenken, Koen

    2015-01-01

    Collaborative Ph.D. projects between university and industry constitute an important aspect of university–industry collaboration, yet has remained under-researched thus far. The specific question this paper asks is how collaborative Ph.D. projects perform compared to non-collaborative Ph.D. projects

  20. PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192.

    Science.gov (United States)

    Moser, Sandra C; Bensaddek, Dalila; Ortmann, Brian; Maure, Jean-Francois; Mudie, Sharon; Blow, J Julian; Lamond, Angus I; Swedlow, Jason R; Rocha, Sonia

    2013-08-26

    PHD1 belongs to the family of prolyl-4-hydroxylases (PHDs) that is responsible for posttranslational modification of prolines on specific target proteins. Because PHD activity is sensitive to oxygen levels and certain byproducts of the tricarboxylic acid cycle, PHDs act as sensors of the cell's metabolic state. Here, we identify PHD1 as a critical molecular link between oxygen sensing and cell-cycle control. We show that PHD1 function is required for centrosome duplication and maturation through modification of the critical centrosome component Cep192. Importantly, PHD1 is also required for primary cilia formation. Cep192 is hydroxylated by PHD1 on proline residue 1717. This hydroxylation is required for binding of the E3 ubiquitin ligase SCF(Skp2), which ubiquitinates Cep192, targeting it for proteasomal degradation. By modulating Cep192 levels, PHD1 thereby affects the processes of centriole duplication and centrosome maturation and contributes to the regulation of cell-cycle progression. Copyright © 2013 The Authors. Published by Elsevier Inc. All rights reserved.

  1. The status of PhD education in economic, social, and administrative sciences between 2005 and 2008.

    Science.gov (United States)

    Farley, Joel F; Wang, Chi-Chuan; Blalock, Susan J

    2010-09-10

    To describe the funding, education, enrollment, and graduation patterns from economic, social, and administrative sciences PhD programs in colleges and schools of pharmacy in the United States. Economic, social, and administrative sciences PhD programs were identified from the American Association of Colleges of Pharmacy (AACP) Web site. A 41-item online survey instrument was sent to the director of graduate studies of each identified program. Only programs offering a PhD degree were included in the study. Of the 26 programs surveyed, 20 (77%) provided useable responses to the survey instrument. Approximately 91% of PhD programs guarantee funding to incoming students with an average commitment of 2.9 years. On average, students were paid a stipend of $18,000 per year for commitments to research and teaching assistantships, each averaging approximately 2 years in length. Programs admitted an average of 3.5 students per year and graduated approximately 85% of entering students. The majority of students are non-US citizens and accept positions in either academic or industrial positions after graduation. Most economic, social, and administrative sciences PhD programs guarantee funding to incoming PhD candidates. Programs offering funding packages significantly below the average may be at a competitive disadvantage. It is unclear whether the number of students graduating from PhD programs is adequate to fulfill academic and industrial needs.

  2. Substrate preference of the HIF-prolyl hydroxylase-2 (PHD2) and substrate-induced conformational change.

    Science.gov (United States)

    Pektas, Serap; Knapp, Michael J

    2013-09-01

    HIF prolyl-4-hydroxylase 2 (PHD2) is a non-heme Fe, 2-oxoglutarate (2OG) dependent dioxygenase that regulates the hypoxia inducible transcription factor (HIF) by hydroxylating two conserved prolyl residues in N-terminal oxygen degradation domain (NODD) and C-terminal oxygen degradation domain (CODD) of HIF-1α. Prior studies have suggested that the substrate preference of PHD2 arises from binding contacts with the β2β3 loop of PHD2. In this study we tested the substrate selectivity of PHD2 by kinetic competition assays, varied ionic strength, and global protein flexibility using amide H/D exchange (HDX). Our results revealed that PHD2 preferred CODD by 20-fold over NODD and that electrostatics influenced this effect. Global HDX monitored by mass spectrometry indicated that binding of Fe(II) and 2OG stabilized the overall protein structure but the saturating concentrations of either NODD or CODD caused an identical change in protein flexibility. These observations imply that both substrates stabilize the β2β3 loop to the same extent. Under unsaturated substrate conditions NODD led to a higher HDX rate than CODD due to its lower binding affinity to PHD2. Our results suggest that loop closure is the dominant contributor to substrate selectivity in PHD2.

  3. 尿KIM-1对心脏术后急性肾损伤的早期诊断价值

    Institute of Scientific and Technical Information of China (English)

    余春俊; 龚明辉; 谭劲淘; 涂星强; 王涛; 邹小明

    2014-01-01

    目的:评估尿肾损伤分子1(KIM-1)在心脏术后急性肾损伤(AKI)早期诊断中的应用价值。方法通过计算机检索Medline、Cochrane图书馆、EMBASE、Web of Science Database、Elsevier Science Direct Database、 CNKI、VIP数据库、万方数据库,查阅KIM-1早期诊断心脏术后AKI的临床试验,采用诊断精确性研究的质量评估方法(QUADAS)评价文献质量,Stata12.0和Meta-Disc1.4软件进行数据分析。结果共纳入9篇符合标准的诊断性研究,QUADAS得分均﹥9分,Spearman异质性检验r=0.622、 P=0.074,发表偏倚Egger线性回归法定量分析P=0.001;敏感性分析的合并敏感度为0.87(95%CI为0.81~0.92)、P=0.5776、I2=0,特异度为0.78(95%CI为0.74~0.81)、P=0.000、I2=87.1%,阳性似然比为4.07(95%CI为2.70~7.12)、P=0.000、I2=78.2%,阴性似然比为0.19(95%CI为0.13~0.28)、P=0.7303、I2=0.0%,诊断比值比为28.03(95%CI为15.95~49.27)、P=0.8640、I2=0,汇总受试者工作曲线下面积(AUC)为0.9155。结论尿KIM-1在心脏术后(6~12h)诊断AKI的准确性较高。

  4. Urinary Vitamin D Binding Protein and KIM-1 Are Potent New Biomarkers of Major Adverse Renal Events in Patients Undergoing Coronary Angiography.

    Directory of Open Access Journals (Sweden)

    Lyubov Chaykovska

    Full Text Available Vitamin-D-binding protein (VDBP is a low molecular weight protein that is filtered through the glomerulus as a 25-(OH vitamin D 3/VDBP complex. In the normal kidney VDBP is reabsorbed and catabolized by proximal tubule epithelial cells reducing the urinary excretion to trace amounts. Acute tubular injury is expected to result in urinary VDBP loss. The purpose of our study was to explore the potential role of urinary VDBP as a biomarker of an acute renal damage.We included 314 patients with diabetes mellitus or mild renal impairment undergoing coronary angiography and collected blood and urine before and 24 hours after the CM application. Patients were followed for 90 days for the composite endpoint major adverse renal events (MARE: need for dialysis, doubling of serum creatinine after 90 days, unplanned emergency rehospitalization or death.Increased urine VDBP concentration 24 hours after contrast media exposure was predictive for dialysis need (no dialysis: 113.06 ± 299.61 ng/ml, n = 303; need for dialysis: 613.07 ± 700.45 ng/ml, n = 11, Mean ± SD, p<0.001, death (no death during follow-up: 121.41 ± 324.45 ng/ml, n = 306; death during follow-up: 522.01 ± 521.86 ng/ml, n = 8; Mean ± SD, p<0.003 and MARE (no MARE: 112.08 ± 302.00 ng/ml, n = 298; MARE: 506.16 ± 624.61 ng/ml, n = 16, Mean ± SD, p<0.001 during the follow-up of 90 days after contrast media exposure. Correction of urine VDBP concentrations for creatinine excretion confirmed its predictive value and was consistent with increased levels of urinary Kidney Injury Molecule-1 (KIM-1 and baseline plasma creatinine in patients with above mentioned complications. The impact of urinary VDBP and KIM-1 on MARE was independent of known CIN risk factors such as anemia, preexisting renal failure, preexisting heart failure, and diabetes.Urinary VDBP is a promising novel biomarker of major contrast induced nephropathy-associated events 90 days after contrast media exposure.

  5. 山西公安机关开展“阳光行动”的文化思考%Cultural Thinking on "Sunny Action" Carried by Shanxi Public Security Organs

    Institute of Scientific and Technical Information of China (English)

    张兆端

    2011-01-01

    Sunny Action" is cultural "brand" project for promoting the level of public security management and work,which needs pushing of soft power of public security culture.The cultural idea of carrying out "sunny Action" is "people-oriented".At present,in order to strengthen cultural soft power,public security organs should stress the police's professional ethics construction,cultivate police's core values,create learning-typed public security organs,build learning-typed public security force,better police public relation,establish police's good image,construct harmonious police camps,close police's interpersonal relationships,carry out police's cultural and sports activities,enrich police's spiritual life,implement the measures of better treatment to police,improve the police's enthusiasm to the work.%"阳光行动"是提升公安队伍管理和公安工作水平的文化"品牌"工程,开展"阳光行动"需要公安文化软实力助推。开展"阳光行动"的文化理念是"以人为本"。当前,公安机关加强文化"软实力"建设,应当抓好几项重点工作:加强人民警察职业道德建设,培育人民警察核心价值观念;创建学习型公安机关,打造学习型公安队伍;搞好警察公共关系,树立警察良好形象;构建和谐警营,密切警察人际关系;开展群众性警察文体活动,丰富警察精神生活;落实从优待警措施,提高警察工作积极性。

  6. Publication rate and PhD enrolment following a medical pre-graduate research programme

    DEFF Research Database (Denmark)

    Skovgaard, Marlene; Okkels, Niels; Christensen, Mette Krogh;

    2015-01-01

    INTRODUCTION: In the 1990s, the publication and PhD recruitment rates following the Danish pre-graduate research programme (PGRP) in medicine were 54% and 33%, respectively. Updated estimates are unknown. METHODS: All medical students enrolled in the PGRP at the Faculty of Medicine, Aarhus......, PGRP completion time and years in medical school at the time of PGRP initiation. Supervisors were described by sex, title, position and affiliation. Calculations were tested by the chi-squared test; p ...: Fast completion of the PGRP and early enrolment in the programme were associated with scientific publishing and PhD recruitment. The publication rate has remained stable over time. FUNDING: Authors were funded by their individual affiliations. TRIAL REGISTRATION: not relevant....

  7. Publication ethics from the perspective of PhD students of health sciences: a limited experience.

    Science.gov (United States)

    Arda, Berna

    2012-06-01

    Publication ethics, an important subtopic of science ethics, deals with determination of the misconducts of science in performing research or in the dissemination of ideas, data and products. Science, the main features of which are secure, reliable and ethically obtained data, plays a major role in shaping the society. As long as science maintains its quality by being based on reliable and ethically obtained data, it will be possible to maintain its role in shaping the society. This article is devoted to the presentation of opinions of PhD candidate students in health sciences in Ankara concerning publication ethics. The data obtained from 143 PhD students from the fields of medicine, dentistry, pharmacy and veterinary reveal limited but unique experiences. It also shows that plagiarism is one of the worst issues in the publication ethics from the perspective of these young academics.

  8. The use of a Virtual Community to Complement the MS PHD'S Professional Development Program

    Science.gov (United States)

    Nieves, I. U.; Brown, D. C.; Bailey, K.; Easley, R.; Johnson, A.; Ithier, W.; Powell, J. M.; Whitney, V. W.; Pyrtle, A. J.

    2005-12-01

    The aim of the Minorities Striving and Pursuing Higher Degrees of Success in Earth System Sciencer Professional Development Program (MS PHD'S PDP) is to provide professional and mentoring experiences that facilitate the advancement of minorities committed to achieving outstanding Earth system science and engineering careers. The MS PHD'S PDP is structured in three phases that are connected by engagement in virtual community building activities, allowing for continuous peer to peer and mentor to mentee interactions. These activities occur through the use of the MSPHD'S website forum and web cam dialogues. In addition, the virtual community provides the personal and professional support necessary to ensure the success of the students. Examples of interactions within the MSPHD'S PDP virtual community will be presented.

  9. Examining the British PhD viva: opening new doors or scarring for life?

    Science.gov (United States)

    Carter, Bernie; Whittaker, Karen

    2009-01-01

    The PhD viva -- regardless of its format -- has the potential to be a significant rite of passage for the student. It is an experience that can resonate for months or years afterwards. Part of the challenge is that for everyone involved -- student, supervisory team and examiners -- a degree of end-point uncertainty exists. These ambiguities and tensions are perhaps an inherent part of any examination but are particularly characteristic of the examination of the individual and unique body of work that constitutes the doctoral thesis. In recent years, increased attention has been placed on the processes that surround the examination, aiming to increase transparency, consistency and fairness. However, the process of examining a student and their thesis remains challenging and is surrounded by different agendas, ideologies and practices. This paper examines some of the issues surrounding the PhD viva, primarily focusing on the British viva whilst weaving in commentary about the Australian system.

  10. Protein interactions of the MLL PHD fingers modulate MLL target gene regulation in human cells.

    Science.gov (United States)

    Fair, K; Anderson, M; Bulanova, E; Mi, H; Tropschug, M; Diaz, M O

    2001-05-01

    The PHD fingers of the human MLL and Drosophila trx proteins have strong amino acid sequence conservation but their function is unknown. We have determined that these fingers mediate homodimerization and binding of MLL to Cyp33, a nuclear cyclophilin. These two proteins interact in vitro and in vivo in mammalian cells and colocalize at specific nuclear subdomains. Overexpression of the Cyp33 protein in leukemia cells results in altered expression of HOX genes that are targets for regulation by MLL. These alterations are suppressed by cyclosporine and are not observed in cell lines that express a mutant MLL protein without PHD fingers. These results suggest that binding of Cyp33 to MLL modulates its effects on the expression of target genes.

  11. Publication rate and PhD enrolment following a medical pre-graduate research programme

    DEFF Research Database (Denmark)

    Skovgaard, Marlene; Okkels, Niels; Christensen, Mette Krogh;

    2015-01-01

    INTRODUCTION: In the 1990s, the publication and PhD recruitment rates following the Danish pre-graduate research programme (PGRP) in medicine were 54% and 33%, respectively. Updated estimates are unknown. METHODS: All medical students enrolled in the PGRP at the Faculty of Medicine, Aarhus......% of the overall 224 papers, and 90% were original articles. Publication was positively associated with completion of the PGRP in related to enrolment in the PGRP after fewer years in medical school. CONCLUSIONS......: Fast completion of the PGRP and early enrolment in the programme were associated with scientific publishing and PhD recruitment. The publication rate has remained stable over time. FUNDING: Authors were funded by their individual affiliations. TRIAL REGISTRATION: not relevant....

  12. The training, careers, and work of Ph.D. physical scientists: Not simply academic

    Science.gov (United States)

    Smith, Steven J.; Pedersen-Gallegos, Liane; Riegle-Crumb, Catherine

    2002-11-01

    We present an in-depth portrait of the training, careers, and work of recent Ph.D. physical scientists. Use of specialized training varies widely, with about half often using knowledge of their Ph.D. specialty area in their jobs. The use of specialized training does not, however, correlate with job satisfaction. In this and other important measures, there are relatively few differences between "academics" and "nonacademics." Important job skills for all employment sectors include writing, oral presentation, management, data analysis, designing projects, critical thinking, and working in an interdisciplinary context. Rankings given by respondents of graduate training in some of these skill areas were significantly lower than the importance of these skills in the workplace. We also found that the rated quality of graduate training varies relatively little by department or advisor. Finally, although nonacademic aspirations among graduate students are fairly common, these do not appear to be well supported while in graduate school.

  13. Phd study of reliability and validity: One step closer to a standardized music therapy assessment model

    DEFF Research Database (Denmark)

    Jacobsen, Stine Lindahl

    The paper will present a phd study concerning reliability and validity of music therapy assessment model “Assessment of Parenting Competences” (APC) in the area of families with emotionally neglected children. This study had a multiple strategy design with a philosophical base of critical realism...... and pragmatism. The fixed design for this study was a between and within groups design in testing the APCs reliability and validity. The two different groups were parents with neglected children and parents with non-neglected children. The flexible design had a multiple case study strategy specifically...... of the theoretical understanding of the clientgroup. Furthermore, a short describtion of the specific assessment protocol and analysis procedures of APC will be a part of the presentation. The phd study sought to explore how to develop measures of parenting competences in looking at autonomy relationship...

  14. Study on the Muon Background in the Underground Laboratory of KIMS%KIMS地下实验中μ子本底的研究

    Institute of Scientific and Technical Information of China (English)

    朱敬军; S.S.Myung; M.J.Lee; S.C.Kim; S.K.Kim; J.I.Lee; Y.D.Kim; M.J.Hwang; Y.J.Kwon; I.S.Hahn; H.J.Kim; 康克军; 李元景; 李金; J.W.Kwak; H.Bhang; S.Y.Kim; H.S.Lee; J.Lee

    2005-01-01

    KIMS是寻找和研究暗物质WIMP的实验组.在WIMP寻找实验中,μ子是十分重要的一种本底.我们对地下700m深的Yangyang实验室内的μ子通量进行了测量.介绍了μ子探测器的结构和性能测试.描述了对μ子入射位置和角度分布的分析,并进行了蒙特卡罗模拟.实验室内的μ子通量测量值为(7.0±0.4)×10-8/s/cm2/sr.%KIMS is a group aiming at the search for WIMP. In WIMP search experiment, the muon is one important background. We measure the muon flux in Yangyang laboratory where is located at 700m underground. The structure and performance test of muon detector is described. The analysis on muon hit position and angle distribution has been performed. The simulations of muon flux have been done. The muon flux in the laboratory is found to be about (7.0±0.4)×10-8/s/cm2/sr.

  15. Evaluation of KIMS immunoassays on a cobas c 501 analyzer for drugs of abuse and ethyl glucuronide testing in urine for forensic abstinence control.

    Science.gov (United States)

    Neukamm, Merja A; Bahrami, Arsham; Auwärter, Volker; Mehne, Felix M P; Höss, Eva

    2016-12-26

    For the medico-psychological assessment (MPA) during driving licence re-granting in Germany, abstinence control including urine samples is required. In these programmes, even small amounts of markers for drug or alcohol abuse have to be detected. Thus, the concentrations of the target compounds are very low, and, in consequence, the sensitivity of the applied screening method has to be much higher than for clinical use. Modified drugs of abuse and ethyl glucuronide immunoassays on a Roche cobas c 501 analyzer were evaluated for precision, accuracy, onboard calibration stability, cross reactivity, sensitivity, and specificity using authentic urine samples. Precision (intra-day and inter-day relative standard deviation (RSD) and accuracy (bias) at three concentrations were 12% or lower for all parameters. The calibrations remained stable (deviations amphetamines (21 days). Satisfactory cross reactivity was determined for the relevant analytes and also for several new psychoactive substances (NPS). The sensitivity was 100% for all parameters except methadone metabolite EDDP (92%) and fully met the sensitivity criteria for MPA urine testing. The presented kinetic interaction of microparticles in a solution (KIMS) immunoassays on a cobas c 501 thus provide a new method to reliably detect drug or alcohol consumption in abstinence control programmes requiring high sensitivity. Copyright © 2016 John Wiley & Sons, Ltd.

  16. Bucharest PhD Training School : Modern Aspects of Quantum Field Theory and Applications

    CERN Document Server

    2015-01-01

    Bucharest 2015 – Modern Aspects of Quantum Field Theory is part of the CERN – SEENET-MTP PhD Training Program, which consists of a number of seminars in theoretical high energy Physics. This is the second seminar organized by this Program. Here are some photos from this event held in Bucharest between 8-14 November 2015. The previous seminar was organized in Belgrade, under the name Belgrade 2015 - Supergravity.

  17. News from TRI’s Country Networks of PhD Theses Writers

    Directory of Open Access Journals (Sweden)

    Alex P. Schmid

    2014-06-01

    Full Text Available The Terrorism Research Initiative (TRI seeks to improve the quality of research on terrorism and counter-terrorism as well as related research on political violence and armed conflict. One instrument is TRI’s annual award for the best doctoral dissertation in this field. Another is the maintenance of national or regional networks of post-graduate students working on their PhD theses.

  18. Including systematic reviews in PhD programmes and candidatures in nursing - 'Hobson's choice'?

    Science.gov (United States)

    Olsson, Cecilia; Ringnér, Anders; Borglin, Gunilla

    2014-03-01

    Nowadays, gathering and synthesising evidence, i.e. conducting systematic reviews, is considered an important part of any health service research endeavour. Reviewing the literature, however suggest that it is not yet common that PhD students/doctoral candidates publish systematic reviews or even include a high quality review of the literature as a part of their PhD programme or candidature. Implying that systematic reviewing skills might not be acquired by going through an education on a postgraduate level. Additionally, scholars debating systematic reviews 'to be or not to be' as a part of research training seem to be sparse, especially within the field of nursing. In this issue for debate, we would like to propose that the absence of systematic reviews' in this context might severely hamper the 'up and coming' researchers as well as the research conducted. We envisage that this lack can have a negative impact on international nursing practice, and therefore propose that systematic reviews should be considered, whenever appropriate, as a mandatory part of any PhD programme or candidature. We believe that abilities in systematic reviewing will be a sought after research skills in the near future. Including systematic reviews would promote i) refined, well-grounded adequate research questions, ii) PhDs with broad and elevated methodological skills, iii) an increased level of evidence based nursing praxis. However, to make this a reality, supervisors, PhD students, and candidates would need to understand the value of this kind of research activity. Finally, lobbying University faculty boards and grant providers that are not inclined to view literature reviews as 'proper' research or as an important part of health service research, needs to be put on the agenda.

  19. PHD fingers in human diseases: Disorders arising from misinterpreting epigenetic marks

    Energy Technology Data Exchange (ETDEWEB)

    Baker, Lindsey A. [Rockefeller University, Laboratory of Chromatin Biology and Epigenetics, 1230 York Avenue, Box 78, New York, NY 10065 (United States); Allis, C. David [Rockefeller University, Laboratory of Chromatin Biology and Epigenetics, 1230 York Avenue, Box 78, New York, NY 10065 (United States)], E-mail: alliscd@rockefeller.edu; Wang, Gang G. [Rockefeller University, Laboratory of Chromatin Biology and Epigenetics, 1230 York Avenue, Box 78, New York, NY 10065 (United States)], E-mail: gwang@rockefeller.edu

    2008-12-01

    Histone covalent modifications regulate many, if not all, DNA-templated processes, including gene expression and DNA damage response. The biological consequences of histone modifications are mediated partially by evolutionarily conserved 'reader/effector' modules that bind to histone marks in a modification- and context-specific fashion and subsequently enact chromatin changes or recruit other proteins to do so. Recently, the Plant Homeodomain (PHD) finger has emerged as a class of specialized 'reader' modules that, in some instances, recognize the methylation status of histone lysine residues, such as histone H3 lysine 4 (H3K4). While mutations in catalytic enzymes that mediate the addition or removal of histone modifications (i.e., 'writers' and 'erasers') are already known to be involved in various human diseases, mutations in the modification-specific 'reader' proteins are only beginning to be recognized as contributing to human diseases. For instance, point mutations, deletions or chromosomal translocations that target PHD fingers encoded by many genes (such as recombination activating gene 2 (RAG2), Inhibitor of Growth (ING), nuclear receptor-binding SET domain-containing 1 (NSD1) and Alpha Thalassaemia and Mental Retardation Syndrome, X-linked (ATRX)) have been associated with a wide range of human pathologies including immunological disorders, cancers, and neurological diseases. In this review, we will discuss the structural features of PHD fingers as well as the diseases for which direct mutation or dysregulation of the PHD finger has been reported. We propose that misinterpretation of the epigenetic marks may serve as a general mechanism for human diseases of this category. Determining the regulatory roles of histone covalent modifications in the context of human disease will allow for a more thorough understanding of normal and pathological development, and may provide innovative therapeutic strategies

  20. Nam obeshtshajut peregrev / Kim Kosmatshov

    Index Scriptorium Estoniae

    Kosmatshov, Kim

    2006-01-01

    Ajakirjas The Economist ilmunud artiklist, milles käsitletakse Eesti ja Läti majandusedu ning viidatakse võimalikele ohtudele tulevikus. Peamiseks probleemiks nimetatakse mõlema riigi puhul inflatsiooni kasvu

  1. Nam obeshtshajut peregrev / Kim Kosmatshov

    Index Scriptorium Estoniae

    Kosmatshov, Kim

    2006-01-01

    Ajakirjas The Economist ilmunud artiklist, milles käsitletakse Eesti ja Läti majandusedu ning viidatakse võimalikele ohtudele tulevikus. Peamiseks probleemiks nimetatakse mõlema riigi puhul inflatsiooni kasvu

  2. "PhD Comics" author Jorge Cham on the power of procrastination

    CERN Document Server

    Stefania Pandolfi

    2015-01-01

    From Tuesday, 22 to Friday, 25 September, Jorge Cham visited CERN. The PHD Movie 2 was screened in the Main Auditorium  and the cartoonist also took part in one of the Researchers' Night events.    Jorge Cham in the CERN Control Centre. On the first day, the author of the comic strip Piled Higher and Deeper (PhD Comics) visited the CERN Control Centre, the Synchrocyclotron, the CMS Service Cavern and the ATLAS control room. On Thursday, he had a busy afternoon, starting with signing copies of his books and then giving a talk entitled “The Power of Procrastination” in a packed Main Auditorium. He made the audience laugh by narrating his experience as a graduate student in robotics at Stanford University, recounting how he started drawing PhD Comics and how it rapidly became popular in universities all over the world. He then analysed the frustrations and anxieties commonly experienced by any graduate student, causing...

  3. Management of Stress and Anxiety Among PhD Students During Thesis Writing: A Qualitative Study.

    Science.gov (United States)

    Bazrafkan, Leila; Shokrpour, Nasrin; Yousefi, Alireza; Yamani, Nikoo

    2016-01-01

    Today, postgraduate students experience a variety of stresses and anxiety in different situations of academic cycle. Stress and anxiety have been defined as a syndrome shown by emotional exhaustion and reduced personal goal achievement. This article addresses the causes and different strategies of coping with this phenomena by PhD students at Iranian Universities of Medical Sciences. The study was conducted by a qualitative method using conventional content analysis approach. Through purposive sampling, 16 postgraduate medical sciences PhD students were selected on the basis of theoretical sampling. Data were gathered through semistructured interviews and field observations. Six hundred fifty-four initial codes were summarized and classified into 4 main categories and 11 subcategories on the thematic coding stage dependent on conceptual similarities and differences. The obtained codes were categorized under 4 themes including "thesis as a major source of stress," "supervisor relationship," "socioeconomic problem," and "coping with stress and anxiety." It was concluded that PhD students experience stress and anxiety from a variety of sources and apply different methods of coping in effective and ineffective ways. Purposeful supervision and guidance can reduce the cause of stress and anxiety; in addition, coping strategy must be in a thoughtful approach, as recommended in this study.

  4. A move-step analysis of the concluding chapters in computer science PhD theses

    Directory of Open Access Journals (Sweden)

    Carmen Soler-Monreal

    2016-11-01

    Full Text Available This paper describes how computer science doctoral writers construct the closing chapters of their PhD theses. The data are drawn from the chapters playing a concluding role of 48 PhD theses defended at the University of Glasgow from 2008 to 2014. The analysis applied a qualitative-quantitative approach. The titles of the concluding chapters of the theses were first examined and also their divisions into sections and sub-sections. Then the chapters were subjected to a move-step analysis: Move 1 (M1 “Revisiting the study”; Move 2 (M2 “Consolidating research space”; Move 3 (M3 “Proposing practical applications and implications”, Move 4 (M4 “Recommending future work” and Move 5 (M5 “Recapitulating the study”. The results revealed that most of the computer science PhD theses have one final concluding chapter with three main moves: M1, M2 and M4. The most frequent steps are “reviewing the work carried out” and “summarizing the specific work reported in every thesis chapter” in M1, “presenting results and contributions”, “answering the initial research questions or hypotheses”, and “making claims” in M2, and “acknowledging limitations” and “suggesting further research” in M4. Movestep patterns appear in recurrent cycles throughout the concluding chapters. Several suggestions for pedagogical purposes are provided.

  5. Pioneering women in American mathematics the pre-1940 PhD's

    CERN Document Server

    Green, Judy

    2008-01-01

    More than 14 percent of the PhD's awarded in the United States during the first four decades of the twentieth century went to women, a proportion not achieved again until the 1980s. This book is the result of a study in which the authors identified all of the American women who earned PhD's in mathematics before 1940, and collected extensive biographical and bibliographical information about each of them. By reconstructing as complete a picture as possible of this group of women, Green and LaDuke reveal insights into the larger scientific and cultural communities in which they lived and worked. The book contains an extended introductory essay, as well as biographical entries for each of the 228 women in the study. The authors examine family backgrounds, education, careers, and other professional activities. They show that there were many more women earning PhD's in mathematics before 1940 than is commonly thought. Extended biographies and bibliographical information are available from the companion website fo...

  6. Research Career Persistence for Solar and Space Physics PhD

    Science.gov (United States)

    Moldwin, Mark B.; Morrow, Cherilynn

    2016-06-01

    Results from a recent graduate student survey found unsurprisingly that Solar and Space Physics (S&SP) PhD graduate students almost all aspire to have research careers in Solar and Space Physics. This study reports on the research career persistence over the first decade of the new millennium for S&SP PhDs. We used publication of science citation indexed articles as the indicator for persistence in a research career. We found that nearly two thirds (64%) of PhDs who graduated between 2001 and 2009 published refereed papers in 2012 or 2013, while 17% of PhDs never published another paper beyond the year they received their PhD. The remaining 19% of PhDs stopped publishing within three years of receiving their PhD. We found no gender difference between research persistence. We also found that though there is statistically no difference on persistence of publishing research between graduates of the largest programs compared to all other programs, there are significant differences between individual programs. This study indicates that a majority of S&SP PhDs find research careers but that a significant fraction pursue careers where publishing in science citation indexed journals is not required. Graduate programs, advisors, and potential graduate students can use these data for career planning and developing mentoring programs that meet the career outcomes of all of their graduates.

  7. Advancing Minorities and Women to the PhD in Physics and Astronomy

    Science.gov (United States)

    Stassun, Keivan

    2017-01-01

    We briefly review the current status of underrepresented minorities in physics and astronomy: The underrepresentation of Black-, Hispanic-, and Native-Americans is an order of magnitude problem. We then describe the Fisk-Vanderbilt Masters-to-PhD Bridge program as a successful model for addressing this problem. Since 2004 the program has admitted 110 students, 90% of them underrepresented minorities (50% female), with a retention rate of 90%. The program has become the top producer of African American master's degrees in physics, and is now one of the top producers of minority PhDs in astronomy, materials science, and physics. We summarize the main features of the program including its core strategies: (1) replacing the GRE in admissions with indicators that are better predictive of long-term success, (2) partnering with a minority-serving institution for student training through collaborative research, and (3) using the master's degree as a deliberate stepping stone to the PhD. We show how misuse of the GRE in graduate admissions may by itself in large part explain the ongoing underrepresentation of minorities in PhD programs, and we describe our alternate methods to identify talented individuals most likely to succeed. We describe our mentoring model and toolkit which may be utilized to enhance the success of all PhD students.

  8. Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

    Directory of Open Access Journals (Sweden)

    Javier Rodriguez

    2016-03-01

    Full Text Available Amino acid hydroxylation is a post-translational modification that regulates intra- and inter-molecular protein-protein interactions. The modifications are regulated by a family of 2-oxoglutarate- (2OG dependent enzymes and, although the biochemistry is well understood, until now only a few substrates have been described for these enzymes. Using quantitative interaction proteomics, we screened for substrates of the proline hydroxylase PHD3 and the asparagine hydroxylase FIH, which regulate the HIF-mediated hypoxic response. We were able to identify hundreds of potential substrates. Enrichment analysis revealed that the potential substrates of both hydroxylases cluster in the same pathways but frequently modify different nodes of signaling networks. We confirm that two proteins identified in our screen, MAPK6 (Erk3 and RIPK4, are indeed hydroxylated in a FIH- or PHD3-dependent mechanism. We further determined that FIH-dependent hydroxylation regulates RIPK4-dependent Wnt signaling, and that PHD3-dependent hydroxylation of MAPK6 protects the protein from proteasomal degradation.

  9. ISO/IEEE 11073 PHD message generation toolkit to standardize healthcare device.

    Science.gov (United States)

    Lim, Joon-Ho; Park, Chanyong; Park, Soo-Jun; Lee, Kyu-Chul

    2011-01-01

    As senior population increases, various healthcare devices and services are developed such as fall detection device, home hypertension management service, and etc. However, to vitalize healthcare devices and services market, standardization for interoperability between device and service must precede. To achieve the standardization goal, the IEEE 11073 Personal Health Device (PHD) group has been standardized many healthcare devices, but until now there are few devices compatible with the PHD standard. One of main reasons is that it isn't easy for device manufactures to implement standard communication module by analyzing standard documents of over 600 pages. In this paper, we propose a standard message generation toolkit to easily standardize existing non-standard healthcare devices. The proposed toolkit generates standard PHD messages using inputted device information, and the generated messages are adapted to the device with the standard state machine file. For the experiments, we develop a reference H/W, and test the proposed toolkit with three healthcare devices: blood pressure, weighting scale, and glucose meter. The proposed toolkit has an advantage that even if the user doesn't know the standard in detail, the user can easily standardize the non-standard healthcare devices.

  10. PhD students' experiences of thesis supervision in Malaysia: managing relationships in the midst of institutional change

    National Research Council Canada - National Science Library

    Krauss, Steven Eric; Ismail, Ismi Arif

    2010-01-01

    Despite the plethora of studies that have been conducted on PhD supervision, little qualitative investigation has been conducted with a diverse, non-Western sample of doctoral students in an attempt...

  11. National, inter-institutional, graduate modules – blended learning approaches for PhD education in Ireland

    OpenAIRE

    Cosgrave, Michael; Murphy, Orla

    2012-01-01

    This paper is a case study that describes the design and delivery of national PhD lectures with 40 PhD candidates in Digital Arts and Humanities in Ireland simultaneously to four remote locations, in Trinity College Dublin, in University College Cork, in NUI Maynooth and NUI Galway. Blended learning approaches were utilized to augment traditional teaching practices combining: face-to-face engagement, video-conferencing to multiple sites, social media lecture delivery support – a live blog and...

  12. Biomedical Science Ph.D. Career Interest Patterns by Race/Ethnicity and Gender.

    Directory of Open Access Journals (Sweden)

    Kenneth D Gibbs

    Full Text Available Increasing biomedical workforce diversity remains a persistent challenge. Recent reports have shown that biomedical sciences (BMS graduate students become less interested in faculty careers as training progresses; however, it is unclear whether or how the career preferences of women and underrepresented minority (URM scientists change in manners distinct from their better-represented peers. We report results from a survey of 1500 recent American BMS Ph.D. graduates (including 276 URMs that examined career preferences over the course of their graduate training experiences. On average, scientists from all social backgrounds showed significantly decreased interest in faculty careers at research universities, and significantly increased interest in non-research careers at Ph.D. completion relative to entry. However, group differences emerged in overall levels of interest (at Ph.D. entry and completion, and the magnitude of change in interest in these careers. Multiple logistic regression showed that when controlling for career pathway interest at Ph.D. entry, first-author publication rate, faculty support, research self-efficacy, and graduate training experiences, differences in career pathway interest between social identity groups persisted. All groups were less likely than men from well-represented (WR racial/ethnic backgrounds to report high interest in faculty careers at research-intensive universities (URM men: OR 0.60, 95% CI: 0.36-0.98, p = 0.04; WR women: OR: 0.64, 95% CI: 0.47-0.89, p = 0.008; URM women: OR: 0.46, 95% CI: 0.30-0.71, p<0.001, and URM women were more likely than all other groups to report high interest in non-research careers (OR: 1.93, 95% CI: 1.28-2.90, p = 0.002. The persistence of disparities in the career interests of Ph.D. recipients suggests that a supply-side (or "pipeline" framing of biomedical workforce diversity challenges may limit the effectiveness of efforts to attract and retain the best and most

  13. Computer tool of the local and remote acquisition of data and the evaluation of grid-connected photovoltaic systems for Control Units of the family Sunny Boy; Programa de monitorizacion remota de instalaciones fotovoltaicas conectadas a red: desarrollo de una plicacion informatica para el control de los sistemas de adquisicion de datos suny data control y suny data control plus

    Energy Technology Data Exchange (ETDEWEB)

    Sidrach-de-Cardona, M.; Carretero, J.; Roman, F.; Garcia, J. D.; Mora-Lopez, L.; Garcia Caballero, J. C.

    2004-07-01

    We present a computer tool that allows the local and remote acquisition of data and the evaluation of grid-connected photovoltaic systems that have inverters and Control Units of the family Sunny Boy. The system is developed in Delphi. This application represents a new point of view in the systems of data acquisition and supposes a substantial improvement regarding the existent ones. It allows the control of the photovoltaic facilities reducing the time of evaluation of the data. (Author)

  14. The Protective Effect of the Ethanol Leaf Extract of Andrographis Paniculata on Cisplatin-Induced Acute Kidney Injury in Rats Through nrf2/KIM-1 Signalling Pathway.

    Science.gov (United States)

    Adeoye, Bisi Olajumoke; Asenuga, Ebunoluwa Racheal; Oyagbemi, Ademola Adetokunbo; Omobowale, Temidayo Olutayo; Adedapo, Adeolu A

    2017-09-12

    The ethanol leaf extract of Andrographis paniculata was used to ameliorate the renal toxicity induced by cisplatin in 28 rats divided into four groups of seven rats per group. Group A received normal saline for the duration of the experiment. Group B animals were treated with cisplatin (10 mg/kg i.p) on day 1 and 3 days after received normal saline for the next 7 days while groups C and D animals also received 10 mg/kg dose of cisplatin on day 1 but after 3 days were then respectively treated with 200 and 400 mg/kg doses of the extract of Andrographis paniculata for the remaining 7 days through oral administration. Serum chemistry was used for the determination of markers of oxidative stress, anti-oxidant enzymes, serum biomarkers etc. Histopathology and immunohistochemistry were also carried out. Results showed that all oxidative stress markers assayed were significantly increased in group B animals but reverse is the case for groups C and D. On the other hand, antioxidant enzymes assayed experienced significant increase for groups C and D while these parameters experienced significant decrease for group B animals. Histopathology showed severe infiltration of inflammatory cells into renal tissues of group B animals whereas for groups C and D animals, only moderate glomerular degeneration was noted. In immunohistochemistry, while there is higher expression of KIM-1 for group B, there was a lower expression in groups C and D. Again, there was lower expression of Nrf2 for group B but higher expressions in groups C and D animals. © Georg Thieme Verlag KG Stuttgart · New York.

  15. Factors that facilitate or inhibit interest of domestic students in the engineering PhD: A mixed methods study

    Science.gov (United States)

    Howell Smith, Michelle C.

    Given the increasing complexity of technology in our society, the United States has a growing demand for a more highly educated technical workforce. Unfortunately, the proportion of United States citizens earning a PhD in engineering has been declining and there is concern about meeting the economic, national security and quality of life needs of our country. This mixed methods sequential exploratory instrument design study identified factors that facilitate or inhibit interest in engineering PhD programs among domestic engineering undergraduate students in the United States. This study developed a testable theory for how domestic students become interested in engineering PhD programs and a measure of that process, the Exploring Engineering Interest Inventory (EEII). The study was conducted in four phases. The first phase of the study was a qualitative grounded theory exploration of interest in the engineering PhD. Qualitative data were collected from domestic engineering students, engineering faculty and industry professional who had earned a PhD in engineering. The second phase, instrument development, developed the Exploring Engineering Interest Inventory (EEII), a measurement instrument designed with good psychometric properties to test a series of preliminary hypotheses related to the theory generated in the qualitative phase. In the third phase of the study, the EEII was used to collect data from a larger sample of junior and senior engineering majors. The fourth phase integrated the findings from the qualitative and quantitative phases. Four factors were identified as being significant influences of interest in the engineering PhD: Personal characteristics, educational environment, misperceptions of the economic and personal costs, and misperceptions of engineering work. Recommendations include increasing faculty encouragement of students to pursue an engineering PhD and programming to correct the misperceptions of the costs of the engineering PhD and the

  16. Building Better Bridges: An Evaluation of The Bridge to the Ph.D. Program

    Science.gov (United States)

    Ellyn Sanderson, Robyn; Lobel, Caroline; Agueros, Marcel A.; Anderson, Vanessa; Ash, Summer; Purdie-Vaughns, Valerie; Romero-Canyas, Rainer; Walker, Erica

    2016-01-01

    Columbia University's Bridge to the Ph.D. in the Natural Sciences Program is increasing the number of underrepresented scholars entering graduate programs and equipping them to succeed in these programs. In a given year, three to five Bridge participants are hired as full-time Columbia University research assistants for up to two years. Now in its seventh year, the Program supports seven participants, and its alumni (including five astronomers) have gone on to Ph.D. programs across the country. Although to date fewer than 40 people have participated in the Program, a number too small for an exclusively statistical evaluation of its effectiveness, we are collecting invaluable longitudinal data on the career progressions of underrepresented aspiring scientists across the natural sciences. At least a dozen Bridge alumni will earn their Ph.D. in the next two-three years, and we will then learn much more about the impact that the Bridge Program has had on our participants' trajectories. Among other things, we hope to use these data to determine the Program's effectiveness in developing feelings of self-efficacy and participants' confidence in their ability to succeed in doctoral programs, to measure the rate at which Bridge alumni successfully complete doctoral programs relative to their peers, and to identify the aspects of the Program that participants find most helpful to their progress at different stages of their paths to and through doctoral programs. Here we describe the data we have already obtained as part of our on-going study, and preliminary results from our analysis.

  17. An interdepartmental Ph.D. program in computational biology and bioinformatics: the Yale perspective.

    Science.gov (United States)

    Gerstein, Mark; Greenbaum, Dov; Cheung, Kei; Miller, Perry L

    2007-02-01

    Computational biology and bioinformatics (CBB), the terms often used interchangeably, represent a rapidly evolving biological discipline. With the clear potential for discovery and innovation, and the need to deal with the deluge of biological data, many academic institutions are committing significant resources to develop CBB research and training programs. Yale formally established an interdepartmental Ph.D. program in CBB in May 2003. This paper describes Yale's program, discussing the scope of the field, the program's goals and curriculum, as well as a number of issues that arose in implementing the program. (Further updated information is available from the program's website, www.cbb.yale.edu.)

  18. Training of young researchers and PhD supervisors for the future

    DEFF Research Database (Denmark)

    Kolmos, Anette

    2004-01-01

    If Europe is to develop an integrated knowledge society and ERA, the research practice has to be developed. Further development of the research practice can among others take place through training of young researchers, which is not only based on the principles of apprenticeship, but a training...... which contributes to break down the usual ways of thinking and to incorporate both intercultural and interdisciplinary principles, and a valued orientation towards trade and industry. The PhD supervisors should also be trained so that light is thrown on the aims, methods and contents of the supervision...

  19. Synthesis of the PhD thesis "Anti-money laundering and counter terrorism financing management"

    Directory of Open Access Journals (Sweden)

    Camelia Popa

    2013-03-01

    Full Text Available As a whole, this PhD thesis follows three research lines, namely: (1 the conceptual line - concerns the definition of the money laundering and terrorism financing phenomenon, the processes, mechanisms, stages and instruments of the laundering of illegally obtained fund; (2 the estimative line aimed at measuring the size of money laundering phenomenon, the economic, social and security effects and consequences; (3 the line of an awareness of the need to prevent and fight against the effects arising from money laundering processes, the national and international efforts taken until present nation- and worldwide and the future measures required to diminish the consequences of this scourge.

  20. Twenty of China's best physics PhD students visited CERN

    CERN Multimedia

    2006-01-01

    Twenty of the top physics PhD students in China were honoured with the 'E=mc2 to modern science' Einstein Award and received a three week tour of major laboratories in Germany and Switzerland, including CERN, DESY and the Max Planck Institute. The Einstein Award is co-sponsored by the German and Swiss Embassies in celebration of the 'Year of Physics' in 2005. For many years, Germany, Switzerland and China have been involved in numerous areas of scientific research and cooperation.

  1. The first Italian doctorate (PhD Course) in Physics Education Research

    Science.gov (United States)

    Michelini, Marisa; Santi, Lorenzo

    2008-05-01

    The first PhD Italian course in Physics Education Research in Udine aims to qualify young researchers and teachers coming from all the Italian groups of research in the field. It becomes a context for developing research projects carried out following parallel research lines on: Teaching/Learning paths for didactic innovation, cognitive research, ICT for strategies to overcome conceptual knots in physics; E-learning for personalization; d) Computer on-line experiments and modelling; e) Teacher formation and training; f) Informal learning in science.

  2. Graduate and Ph.D. Course on Design and Manufacture of Micro Mechanical Systems

    DEFF Research Database (Denmark)

    Hansen, Hans Nørgaard; De Grave, Arnaud

    2011-01-01

    at the Department of Mechanical Engineering at the Technical University of Denmark. This paper describes the framework of the course that has been applied both at graduate and Ph.D. level. The current structure of the course as well as the pedagogical approach and some examples of final projects will be presented...... it is now well known that micro/nanotechnology is not only a matter of downscaling applications and methods from the macro scale, and therefore an in-depth understanding and knowledge of product and process characteristics at this scale is necessary. Based on this challenge, a new course was developed...

  3. Inhibition of PHD3 by salidroside promotes neovascularization through cell–cell communications mediated by muscle-secreted angiogenic factors

    Science.gov (United States)

    Zhang, Jing; Kasim, Vivi; Xie, Yu-Dan; Huang, Can; Sisjayawan, Julita; Dwi Ariyanti, Agnes; Yan, Xue-Song; Wu, Xiao-Yan; Liu, Cai-Ping; Yang, Li; Miyagishi, Makoto; Wu, Shou-Rong

    2017-01-01

    Therapeutic angiogenesis has been considered as a potential strategy for treating peripheral artery diseases including hind-limb ischemia (HLI); however, no effective drug-based treatment is currently available. Here we showed that intramuscular administration of salidroside, an active compound of Chinese herb Rhodiola, could robustly enhance blood perfusion recovery by promoting neovascularization in HLI mice. We revealed that salidroside promoted skeletal muscle cell migration and paracrine function through inhibiting the transcriptional level of prolyl-hydroxylase domain 3 (PHD3) without affecting PHD1 and PHD2. Paracrine signals from salidroside-treated skeletal muscle cells enhanced endothelial and smooth muscle cells migration, while inhibition of FGF2/FGF2R and PDGF-BB/PDGFR-β pathways abolished this effect, as well as neovascularization in HLI mice. Furthermore, we elucidated that salidroside inhibition on PHD3 might occur through estrogen receptor alpha (ERα). Together, our findings highlights the potential application of salidroside as a novel pharmalogical inhibitor of ERα/PHD3 axis for therapeutic angiogenesis in HLI diseases. PMID:28266625

  4. A theoretical model for calculation of molecular stopping power. Ph.D. Thesis

    Science.gov (United States)

    Xu, Y. J.

    1984-01-01

    A modified local plasma model is established. The Gordon-Kim's molecular charged density model is employed to obtain a formula to evaluate the stopping power of many useful molecular systems. The stopping power of H2 and He gas was calculated for incident proton energy ranging from 100 keV to 2.5 MeV. The stopping power of O2, N2, and water vapor was also calculated for incident proton energy ranging from 40 keV. to 2.5 MeV. Good agreement with experimental data was obtained. A discussion of molecular effects leading to department from Bragg's rule is presented. The equipartition rule and the effect of nuclear momentum recoiling in stopping power are also discussed.

  5. Next gen PhD a guide to career paths in science

    CERN Document Server

    Sinche, Melanie V

    2016-01-01

    For decades, top scientists in colleges and universities pursued a clear path to success: enroll in a prestigious graduate program, conduct research, publish papers, complete the PhD, pursue postdoctoral work. With perseverance and a bit of luck, a tenure-track professorship awaited at the end. In today s academic job market, this scenario represents the exception. As the number of newly conferred science PhDs keeps rising, the number of tenured professorships remains stubbornly stagnant. Only 14 percent of those with PhDs in science occupy tenure-track positions five years after completing their degree. Next Gen PhD provides a frank and up-to-date assessment of the current career landscape facing science PhDs. Nonfaculty careers once considered Plan B are now preferred by the majority of degree holders, says Melanie Sinche. An upper-level science degree is a prized asset in the eyes of many employers, and a majority of science PhDs build rewarding careers both inside and outside the university. A certified ...

  6. Home healthcare settop-box for senior chronic care using ISO/IEEE 11073 PHD standard.

    Science.gov (United States)

    Lim, Joon-Ho; Park, Chanyong; Park, Soo-Jun

    2010-01-01

    As the number of seniors with chronic disease increases, the need of home healthcare settop-box is increased to manage their chronic disease in their home environment. Using the home healthcare settop-box, the patients can regularly check their health data, and finally, it can lead the decrease of medical expenses. For the home healthcare settop-box, the most important factor is the standard compatibility, which can interoperate with standard devices of any other companies. In this paper, we propose a home healthcare settop-box using ISO/IEEE 11073 PHD standard. It collects health data according to the PHD standard, and provides a chronic-care service based on the collected data. The proposed settop-box is connected with 3 devices of weigh scale, blood pressure monitor, and glucose meter, and tested at 10 homes for a month. Lastly, the proposed settop-box can be used for various healthcare services such as Google Health and Telemedicine Services using a healthcare platform server.

  7. First ‘Gentner Doktor’ finishes PhD at CERN

    CERN Multimedia

    Jordan Juras

    2011-01-01

    In 2007, the CERN Doctoral Student Programme saw the addition of the Gentner Doctoral Student Programme, named in honour of the celebrated nuclear physicist, Wolfgang Gentner. Four years later, on 22 June 2011, Marcel Schuh finished his PhD with a thesis in the field of accelerator technology and became the very first ‘Gentner Doktor’.   Marcel Schuh, first 'Gentner Doktor', celebrates completing his PhD. (Photo by Carsten P. Welsch) Marcel Schuh became a Gentner student in April 2008, after completing a physics degree in 2007 at the University of Heidelberg. His thesis allowed him to gain exposure to CERN and the LHC, as he worked on monitoring and control systems for trigger and readout electronics on the ALICE detector at the LHC. With the support of university supervisor, Carsten P. Welsch, Schuh applied for a Gentner Doctoral Studentship on the Superconducting Proton Linac (SPL) project. “My task was to evaluate whether dedicated higher order mode (HOM) coupler...

  8. Columbia's Bridge to the Ph.D. Program: A research-focused initiative facilitating the transition to graduate school

    Science.gov (United States)

    Agüeros, Marcel A.

    2015-01-01

    Columbia University's Bridge to the Ph.D. in the Natural Sciences Program aims to enhance the participation of students from underrepresented groups in Ph.D. programs. To achieve this, the Bridge Program provides an intensive research, coursework, and mentoring experience to post-baccalaureates seeking to strengthen their graduate school applications and to prepare for the transition into graduate school. To date, 20 Bridge Program alumni --- including four in astronomy --- have gone on to Ph.D. programs at Columbia, the University of Michigan, Johns Hopkins, the University of Washington, Albert Einstein, Yale, and SUNY-Albany, among others. In this talk, I will touch on some of the connections between Pre-MAP and the Bridge Program, and particularly how my involvement in the former prepared me to lead the latter.

  9. Short Hairpin RNA Silencing of PHD-2 Improves Neovascularization and Functional Outcomes in Diabetic Wounds and Ischemic Limbs.

    Directory of Open Access Journals (Sweden)

    Kevin J Paik

    Full Text Available The transcription factor hypoxia-inducible factor 1-alpha (HIF-1α is responsible for the downstream expression of over 60 genes that regulate cell survival and metabolism in hypoxic conditions as well as those that enhance angiogenesis to alleviate hypoxia. However, under normoxic conditions, HIF-1α is hydroxylated by prolyl hydroxylase 2, and subsequently degraded, with a biological half-life of less than five minutes. Here we investigated the therapeutic potential of inhibiting HIF-1α degradation through short hairpin RNA silencing of PHD-2 in the setting of diabetic wounds and limb ischemia. Treatment of diabetic mouse fibroblasts with shPHD-2 in vitro resulted in decreased levels of PHD-2 transcript demonstrated by qRT-PCR, higher levels of HIF-1α as measured by western blot, and higher expression of the downstream angiogenic genes SDF-1 and VEGFα, as measured by qRT-PCR. In vivo, shPHD-2 accelerated healing of full thickness excisional wounds in diabetic mice compared to shScr control, (14.33 ± 0.45 days vs. 19 ± 0.33 days and was associated with an increased vascular density. Delivery of shPHD-2 also resulted in improved perfusion of ischemic hind limbs compared to shScr, prevention of distal digit tip necrosis, and increased survival of muscle tissue. Knockdown of PHD-2 through shRNA treatment has the potential to stimulate angiogenesis through overexpression of HIF-1α and upregulation of pro-angiogenic genes downstream of HIF-1α, and may represent a viable, non-viral approach to gene therapy for ischemia related applications.

  10. The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers.

    Directory of Open Access Journals (Sweden)

    Nada Lallous

    Full Text Available The human UHRF1 protein (ubiquitin-like containing PHD and RING finger domains 1 has emerged as a potential cancer target due to its implication in cell cycle regulation, maintenance of DNA methylation after replication and heterochromatin formation. UHRF1 functions as an adaptor protein that binds to histones and recruits histone modifying enzymes, like HDAC1 or G9a, which exert their action on chromatin. In this work, we show the binding specificity of the PHD finger of human UHRF1 (huUHRF1-PHD towards unmodified histone H3 N-terminal tail using native gel electrophoresis and isothermal titration calorimetry. We report the molecular basis of this interaction by determining the crystal structure of huUHRF1-PHD in complex with the histone H3 N-terminal tail. The structure reveals a new mode of histone recognition involving an extra conserved zinc finger preceding the conventional PHD finger region. This additional zinc finger forms part of a large surface cavity that accommodates the side chain of the histone H3 lysine K4 (H3K4 regardless of its methylation state. Mutation of Q330, which specifically interacts with H3K4, to alanine has no effect on the binding, suggesting a loose interaction between huUHRF1-PHD and H3K4. On the other hand, the recognition appears to rely on histone H3R2, which fits snugly into a groove on the protein and makes tight interactions with the conserved aspartates D334 and D337. Indeed, a mutation of the former aspartate disrupts the formation of the complex, while mutating the latter decreases the binding affinity nine-fold.

  11. The Road to Become a Legitimate Scholar: A Case Study of International PhD Students in Science and Engineering

    Directory of Open Access Journals (Sweden)

    Pia Bøgelund

    2015-11-01

    Full Text Available The purpose of the doctoral education process is to create and legitimize scholarly researchers. This transformation, from student to scholar, is widely discussed in the literature. However, recent rapid changes in university culture have resulted in less time for supervision, stricter completion deadlines, and a greater focus on efficiency and productivity. This has had an impact on this transition process, and this impact has not been widely studied. The aim of this article is to understand the consequences of the current trends for PhD students and the education of PhD students in general. The article is based on interviews with 14 international students from two different research programs at the Faculty of Engineering and Science at Aalborg University in Denmark. The case of international PhD students in a western setting is singled out as a challenging case for becoming a legitimate scholar, since they face the additional challenge of becoming socialised into their new foreign setting. Overall, the study concludes that the transition process of doctoral students is affected by the way different supervisors deal with current university trends and how PhD students fit or do not fit into their knowledge production practices. The study identifies matches or mismatches in a knowledge production perspective, quality of contact, and degree of independence of the PhD student as factors that influence whether a transition process can be marked as sound, troublesome, or lacking. Finally, the study identifies an overall risk of neglecting the more interdependent types of international PhD students. Suggestions are given as how to address this risk.

  12. LHC Report: Cloudy with sunny spells

    CERN Multimedia

    Lionel Herblin & Mike Lamont for the LHC team

    2015-01-01

    The LHC is continuing its 25 ns intensity ramp-up and has now reached 1465 bunches per beam. Performance is reasonable and the experiments have seen some long fills with steadily increasing luminosity delivery rates. Some now familiar issues continue to make life interesting.   The image shows the heat load evolution as measured in specially equipped dipoles. (Image: Giovanni Iadarola). Top frame: energy and intensity. Middle frame: measured heat load in W/m. Bottom frame: heat load normalised to total beam intensity. One of the key challenges of 2015 was always expected to be electron clouds. The two scrubbing runs that were performed in the summer successfully qualified the LHC for up to around 1500 bunches. However, the final phase of the scrubbing, which saw the move from regular 25 ns beam to the doublet beam, proved difficult, and the scrubbing team concluded that the machine was not yet well-enough scrubbed for the doublets to be used effectively. The 25 ...

  13. A sunny spell at the Pension Fund

    CERN Multimedia

    Association du personnel

    2006-01-01

    It is always nice to receive good news, especially at this time. That of the disappearance of the Organization's debt to the Pension Fund, by a Council decision in June, was a relief to us. That of the very good return in 2005 (+12.4%) on the Fund's investments only partly reassured us after carefully reading the last report by the actuary. In his last editorial (CERN Bulletin 27/28), the Director-General considers that "the news from the Pension Fund is good". We are not so optimistic.

  14. Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis

    DEFF Research Database (Denmark)

    Madsen, Chris D; Pedersen, Jesper Thorhauge; Venning, Freja A;

    2015-01-01

    Cancer-associated fibroblasts (CAFs) interact with tumour cells and promote growth and metastasis. Here, we show that CAF activation is reversible: chronic hypoxia deactivates CAFs, resulting in the loss of contractile force, reduced remodelling of the surrounding extracellular matrix and......, which can be prevented by simultaneous depletion of HIF-1α. Treatment with the PHD inhibitor DMOG in an orthotopic breast cancer model significantly decreases spontaneous metastases to the lungs and liver, associated with decreased tumour stiffness and fibroblast activation. PHD2 depletion in CAFs co...

  15. Customizing Process to Align with Purpose and Program: The 2003 MS PHD'S in Ocean Sciences Program Evaluative Case Study

    Science.gov (United States)

    Williamson, V. A.; Pyrtle, A. J.

    2004-12-01

    How did the 2003 Minorities Striving and Pursuing Higher Degrees of Success (MS PHD'S) in Ocean Sciences Program customize evaluative methodology and instruments to align with program goals and processes? How is data captured to document cognitive and affective impact? How are words and numbers utilized to accurately illustrate programmatic outcomes? How is compliance with implicit and explicit funding regulations demonstrated? The 2003 MS PHD'S in Ocean Sciences Program case study provides insightful responses to each of these questions. MS PHD'S was developed by and for underrepresented minorities to facilitate increased and sustained participation in Earth system science. Key components of this initiative include development of a community of scholars sustained by face-to-face and virtual mentoring partnerships; establishment of networking activities between and among undergraduate, graduate, postgraduate students, scientists, faculty, professional organization representatives, and federal program officers; and provision of forums to address real world issues as identified by each constituent group. The evaluative case study of the 2003 MS PHD'S in Ocean Sciences Program consists of an analysis of four data sets. Each data set was aligned to document progress in the achievement of the following program goals: Goal 1: The MS PHD'S Ocean Sciences Program will successfully market, recruit, select, and engage underrepresented student and non-student participants with interest/ involvement in Ocean Sciences; Goal 2: The MS PHD'S Ocean Sciences Program will provide meaningful engagement for participants as determined by quantitative analysis of user-feedback; Goal 3: The MS PHD'S Ocean Sciences Program will provide meaningful engagement for participants as determined by qualitative analysis of user-feedback, and; Goal 4: The MS PHD'S Ocean Sciences Program will develop a constituent base adequate to demonstrate evidence of interest, value, need and sustainability in

  16. Are MS in Economics Programs in Departments That Also Have a PhD Program in Economics Different from Their Counterparts?

    Science.gov (United States)

    Milkman, Martin I.; Marjadi, Riza; McCoy, James P.

    2016-01-01

    This is the first article that compares terminal master's degree programs in economics from universities that have a PhD program in economics with those that do not offer PhD programs in economics. The authors compare these differences based on surveys in 2002 and 2012. They examine differences in general program characteristics, department…

  17. Serving Many Masters: The PhD on the Labour Market, the Everlasting Need of Inequality, and the Premature Death of Humboldt.

    Science.gov (United States)

    Enders, Jurgen

    2002-01-01

    Surveyed German doctoral degree holders to examine the processes and outcomes of doctoral training and their impact on subsequent careers and work affiliations. Found a positive outcome of the Ph.D. on the labor market, and that selection for doctoral training is biased by social origin while later career attainment among Ph.D. holders is not. (EV)

  18. Are MS in Economics Programs in Departments That Also Have a PhD Program in Economics Different from Their Counterparts?

    Science.gov (United States)

    Milkman, Martin I.; Marjadi, Riza; McCoy, James P.

    2016-01-01

    This is the first article that compares terminal master's degree programs in economics from universities that have a PhD program in economics with those that do not offer PhD programs in economics. The authors compare these differences based on surveys in 2002 and 2012. They examine differences in general program characteristics, department…

  19. Optimization of Intracellular Transportation of Gene Therapeutic DNA in Small Cell Lung Cancer (Ph.d.)

    DEFF Research Database (Denmark)

    Cramer, Frederik

    2013-01-01

    -viral delivery system, to the nuclei of the SCLC cells. As a result, the gene therapy expression obtained is too low to have any clinical relevance. We have at the Department of Radiation Biology developed a transcriptionally targeting suicide gene therapy system which is built on a double stranded DNA plasmid...... framework. One of the most significant barriers for efficient plasmid transport however, is the nuclear envelope that compartmentalizes the transcriptional machinery from the translational in a human cell. As only a small fraction of plasmids is able to breach the nuclear envelope and gain access...... to the transcriptional machinery many attempts have been made to improve nuclear translocation of therapeutic plasmids in order to gain a better gene therapy outcome. The aim of this PhD project was to investigate if the intracellular translocation of our gene therapeutic system could be optimized in SCLC cells...

  20. Frizzled to finance: one PhD's path from a Drosophila lab to Wall Street.

    Science.gov (United States)

    Taylor, Job

    2016-06-01

    An equity research analyst's job is to determine whether the price of a stock is likely to go up or down. For science-based businesses, particularly biotechnology companies, a PhD in the life sciences can be very helpful in making this determination. I transitioned from a postdoc position to working in equity research. Here I present information on how I made the transition, an overview of the day-to-day activities of an analyst, and thoughts on how to prepare to look for a job in finance. There are significant positives to working on Wall Street, including exposure to cutting-edge clinical/translational research, access to some of the best scientists in the world, a dynamic work environment, and compensation that generally exceeds academic salaries. This comes at the cost of some independence and the satisfaction of being able to call oneself a scientist.

  1. Developing PhD Nurse Scientists: Do Bachelor of Science in Nursing Honors Programs Help?

    Science.gov (United States)

    Neuberger, Geri B

    2016-10-01

    The critical need for more nurses with research doctoral degrees to replace vacancies among retiring nursing faculty and nurse administrators is identified. The Future of Nursing report recommends that the number of nurses with PhD degrees double by 2020. Encouraging nursing students to begin doctoral education early in their careers is essential to meeting this goal now and in the future. One method to promote early enrollment into doctoral education is participation in a bachelor of science in nursing (BSN) honors program. We describe the recruitment and application process, mentor selection, scholarly activities, and publication of final manuscripts for one such program. The success of one BSN honors program in enabling graduation with university honors and encouraging enrollment and graduation with doctoral degrees is described. The development of more BSN Honors programs and enhancement of activities of current programs are recommended. [J Nurs Educ. 2016;55(10):579-582.]. Copyright 2016, SLACK Incorporated.

  2. PHD--an automatic mail server for protein secondary structure prediction.

    Science.gov (United States)

    Rost, B; Sander, C; Schneider, R

    1994-02-01

    By the middle of 1993, > 30,000 protein sequences has been listed. For 1000 of these, the three-dimensional (tertiary) structure has been experimentally solved. Another 7000 can be modelled by homology. For the remaining 21,000 sequences, secondary structure prediction provides a rough estimate of structural features. Predictions in three states range between 35% (random) and 88% (homology modelling) overall accuracy. Using information about evolutionary conservation as contained in multiple sequence alignments, the secondary structure of 4700 protein sequences was predicted by the automatic e-mail server PHD. For proteins with at least one known homologue, the method has an expected overall three-state accuracy of 71.4% for proteins with at least one known homologue (evaluated on 126 unique protein chains).

  3. Introduction to EU Grants and Fellowships for PhD students and early Post-docs

    Directory of Open Access Journals (Sweden)

    Epp Julia

    2013-04-01

    Full Text Available This talk is based on the presentation “Introduction to EU Grants and Fellowships for PhD students and early Post-docs” and aims at informing young scientists about individual funding schemes in FP7 Specific Programmes “People” and “Ideas”. It also aims at encouraging young scientists employed at Max Planck Institutes in the “Regional Cluster Bavaria”, or scientists who wish to come to Max Planck Institutes which are part of the cluster, to benefit from the support of the Regional EU Office Bavaria, whose consultants can give valuable administrative and tailor-made internal advice to add on the success of a competitive scientific proposal.

  4. Researcher Profile: An Interview with Sonya Britt, Ph.D., CFP, AFC

    Directory of Open Access Journals (Sweden)

    Sonya Britt

    2013-08-01

    Full Text Available Sonya Britt, Ph.D., CFP, AFC graduated from Texas Tech University in 2010 with a doctorate in Personal Financial Planning. Her first two degrees are from Kansas State University in Personal Financial Planning (B.S. and Marriage and Family Therapy (M.S.. and she was the founding president of the Financial Therapy Association and recently retired from the board as past-president. She currently serves on the board of the American Council on Consumer Interests association. Sonya is an associate editor for the Journal of Family and Economic Issues and on the editorial board of the Journal of Financial Therapy and on the international scientific board of the Italian Journal of Sociology of Education.

  5. Researcher Profile: An Interview with John E. Grable, Ph.D., CFP(R

    Directory of Open Access Journals (Sweden)

    John Grable

    2014-08-01

    Full Text Available John E. Grable, Ph.D., CFP(R teaches and conducts research in the Certified Financial Planner(TM Board of Standards undergraduate and graduate programs at the University of Georgia. Prior to entering the academic profession, he worked as a pension/benefits administrator and later as a Registered Investment Advisor in an asset management firm. He served as the founding editor for the Journal of Personal Finance and as the co-founding editor of the Journal of Financial Therapy. His research interests include financial risk-tolerance assessment, psychophysiological economics, and financial planning help-seeking behavior. Dr. Grable has published nearly 100 peer-reviewed papers, co-authored two financial planning textbooks, and co-edited a financial planning and counseling scales book. He currently writes a quarterly column for the Journal of Financial Service Professionals, serves as academic consultant to the Journal of Financial Planning, and chair the CFP Board Council on Education.

  6. Preliminary and Partial Inventory of PhD Theses and their Authors

    Directory of Open Access Journals (Sweden)

    Coordinators TRI's National Network

    2013-04-01

    Full Text Available The mission statement of the Terrorism Research Initiative (TRI is “Enhancing Security through Collaborative Research”. TRI has been encouraging young scholars who are in the process of writing their PhD theses to link up and collaborate with fellow researchers in their own countries. As a result, post-graduate students have begun to interact for their own mutual benefit and for the good of the wider research community. In fact, in a number of cases several senior, post-doctoral scholars have also joined TRI’s national networks of those studying terrorism, political violence and armed conflict, and ways to prevent and counter such threats to human security. 

  7. Fundraising for Accelerated Study for the PhD in Nursing: A Community Partnership.

    Science.gov (United States)

    Starck, Patricia L

    2015-01-01

    This article describes fundraising strategies by a School of Nursing to support a post-master's accelerated (3-year) PhD degree program. A sample proposal to solicit funds is included, as well as a contract that students sign before accepting the scholarship and agreeing to teach for 3 years or repay the money. The first campaign raised $2.3 million for ten students, and the second campaign raised $1.3 million for six students. One useful marketing strategy is to show the impact of an investment in educating ten doctoral students who will become faculty and teach 100 additional students per year, who will then become professionals caring for thousands of patients during their careers. Over a 10 year period, the impact of an accelerated program is enormous, with 660 students taught who in their lifetime will care for 2.4 million patients. The article also discusses motivation and mind sets for giving to promote success in fundraising.

  8. Researcher Profile: An Interview with Virginia Solis Zuiker, Ph.D.

    Directory of Open Access Journals (Sweden)

    Virginia Solis Zuiker

    2015-12-01

    Full Text Available Virginia Solis Zuiker is an Associate Professor in the Department of Family Social Science at the University of Minnesota. She teaches courses on personal and family finance, family financial counseling, family resource management, economic perspectives of families, and family decision-making. Her scholarly research focus is in the area of economic well-being of families with particular interest in self-employment and family-owned businesses. Her research focuses on the Hispanic family life and she is the author of “Hispanic Self-Employment in the Southwest: Rising Above the Threshold of Poverty,” (Garland Publishing, 1997. She received her B.S. from the University of North Texas, an M.S. from Texas Tech University, and a Ph.D. from The Ohio State University. She served three years on the Board of Directors for the Association of Financial Counseling and Planning Education.

  9. Factors Influencing the Degree Progress of International PhD Students from Africa: An Exploratory Study

    Directory of Open Access Journals (Sweden)

    Almoustapha Oumarou Soumana

    2017-05-01

    Full Text Available In recent decades some countries of the Middle East have offered facilities to attract international students to pursue their higher education within their higher education institutions. The purpose of this study is to understand the difficulties faced by these students while conducting their studies abroad, and in doing so, to broaden the awareness of the challenges they face to complete their research. The participants of this qualitative study are international PhD students studying at a Middle Eastern public university. The university has reported increasing enrollment of international students, particularly from Africa in the last few years. Data were collected using a set of semi-structured interviews that drew out information on critical incidents that characterized the kind of difficulties students had faced in their studies. The data collected was further analyzed using a qualitative software package, NVivo (QSR International, 11. Six main themes came out from the content analysis of the interviews, which are the role of the adviser, student features, funding issues, family engagement, research and psychological obstacles which provide a holistic picture of student perspectives on the factors that influence degree progress. While these students might have faced difficulties mentioned in existing literature, this study argues that the participants have indicated experiencing psychological obstacles that were not described in earlier studies, such as the state of mind they were in as a result of being worried for family members due to war or violence in their home countries, and drop in currency exchange rates and difficulties in acquiring money due to international sanctions imposed against their countries. This study provides important thoughts on the factors that impact the degree progress of international PhD students from Africa, while at the same time revealing a serious gap in the advisers’ role which can contribute to the

  10. Interview with the expert: William E. Collins, Ph.D. Interviewed by Vicki Glaser.

    Science.gov (United States)

    Collins, William E

    2009-10-01

    William Collins, Ph.D., received his B.S. and M.Sc. degrees in entomology from Michigan State University. He completed his Ph.D. at Rutgers University in two years, just before being inducted into the Army to serve in the Korean War. He was assigned to Fort Detrick at the Biological Warfare Research Laboratories and after three years returned to Rutgers as an extension entomologist. He accepted a position in 1959 with the U.S. Public Health Service, with which he has worked for the last 50 years. In 1963, the Public Health Service laboratory moved to Atlanta and Dr. Collins' group began working with non-human primates following the discovery that monkey malarias were transmissible to humans. Parasites from monkeys or apes isolated in Asia, South America, and Africa were sent to the laboratory in Chamblee, Georgia, where they were adapted and transmitted to laboratory-maintained primates and their life cycles described and characterized. Transmissions to human volunteers were also attempted. In 1973, the laboratory operation was transferred to the CDC, and the emphasis changed from the study of monkey malaria in monkeys to that of human malaria in monkeys. During the last 25 to 30 years, different isolates of human malaria parasites have been adapted to New World monkeys to characterize the isolates for the development and testing of drugs and vaccines. Dr. Collins' task has been to identify and choose the best combination of vector-parasite-host combinations for testing each vaccine candidate. He has co-authored more than 450 manuscripts and has been awarded the U.S. Public Health Service Superior Service Award, The Joseph A. LaPrince Medal for Malariology from the American Society of Tropical Medicine and Hygiene, The Distinguished Service Award of the Department of Health and Human Services, the William Watson Medal of Excellence from the Centers for Disease Control and Prevention, and the Hoogstraal Medal from the American Committee of Medical Entomology.

  11. PhD Students' Experiences of Thesis Supervision in Malaysia: Managing Relationships in the Midst of Institutional Change

    Science.gov (United States)

    Krauss, Steven Eric; Ismail, Ismi Arif

    2010-01-01

    Despite the plethora of studies that have been conducted on PhD supervision, little qualitative investigation has been conducted with a diverse, non-Western sample of doctoral students in an attempt to understand how the supervisory relationship is experienced. In response, eighteen students from diverse, non-Western backgrounds studying at one…

  12. Now or Later?: An Empirical Investigation of When and Why Students Apply to Clinical Psychology PhD Programs

    Science.gov (United States)

    Zimak, Eric H.; Edwards, Katie M.; Johnson, Shannon M.; Suhr, Julie

    2011-01-01

    This study used a national sample of PhD students in clinical psychology (N = 1,034) to explore when students decided to pursue their graduate degree, reasons for their decisions, and associated satisfaction. Results indicated that immediately after completing their undergraduate degree, 57% of current graduate students reported postponing…

  13. PhD Topic Arrangement in "D"iscourse Communities of Engineers and Social Sciences/Humanities

    Science.gov (United States)

    Hasrati, Mostafa; Street, Brian

    2009-01-01

    This article is the result of a grounded theory investigation into the ways PhD topics are assigned by supervisors in engineering and selected by students in the social sciences/humanities in UK universities, broadly referred to as "topic arrangement", which can be regarded as one aspect of academic socialisation into academic Discourse…

  14. Who Am I versus Who Can I Become? Exploring Women's Science Identities in STEM Ph.D. Programs

    Science.gov (United States)

    Szelényi, Katalin; Bresonis, Kate; Mars, Matthew M.

    2016-01-01

    This article explores the science identities of 21 women STEM Ph.D. students at three research universities in the United States. Following a narrative approach, the findings depict five salient science identities, including those of a) academic, b) entrepreneurial, c) industrial, and d) policy scientist and e) scientist as community educator. Our…

  15. Who Am I versus Who Can I Become? Exploring Women's Science Identities in STEM Ph.D. Programs

    Science.gov (United States)

    Szelényi, Katalin; Bresonis, Kate; Mars, Matthew M.

    2016-01-01

    This article explores the science identities of 21 women STEM Ph.D. students at three research universities in the United States. Following a narrative approach, the findings depict five salient science identities, including those of a) academic, b) entrepreneurial, c) industrial, and d) policy scientist and e) scientist as community educator. Our…

  16. Learning to Write a Research Article: Ph.D. Students' Transitions toward Disciplinary Writing Regulation

    Science.gov (United States)

    Castello, Montserrat; Inesta, Anna; Corcelles, Mariona

    2013-01-01

    This paper presents a study designed from a socially situated and activity theory perspective aimed at gaining a deeper understanding of how Ph.D. students regulate their academic writing activity. Writing regulation is a complex activity of a highly situated and social nature, involving cyclical thought-action-emotion dynamics and the…

  17. On the Importance of PhD Institute in Establishing a Long-Term Research Career in Astronomy

    CERN Document Server

    Gibson, B K; Vassiliadis, E; Sevenster, M N; Jones, D H; Thornberry, R K; Gibson, Brad K.; Buxton, Michelle; Vassiliadis, Emanuel; Sevenster, Maartje N.; Thornberry, Rebecca K.

    1999-01-01

    We have examined the success rates of 19 American, Canadian, Australian, and Dutch graduate programs in producing astronomers. A 20-year baseline was considered (1975-1994), incorporating 897 PhD recipients. The major conclusion from our study is that the fraction of PhD graduates still involved in astronomical research is surprisingly insensitive to the institutional source of one's PhD. With few exception, 55-75% of graduates, regardless of PhD source, remain active in the astronomical research community. While it remains true that graduates of so-called ``prestigious'' programs preferentially populate the same, it is also clear that an abundance of opportunities exist at smaller ``non-prestigious'' institutions, liberal arts colleges, government, and industry. The latter, of course, generally carry enhanced administrative and/or teaching duties, but, on the other hand, do not entirely preclude a role in the research community. A Kepler-Meier survival analysis of two disparate institutes demonstrates that `...

  18. PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression

    Energy Technology Data Exchange (ETDEWEB)

    Rajakumara, Eerappa; Wang, Zhentian; Ma, Honghui; Hu, Lulu; Chen, Hao; Lin, Yan; Guo, Rui; Wu, Feizhen; Li, Haitao; Lan, Fei; Shi, Yujiang Geno; Xu, Yanhui; Patel, Dinshaw J.; Shi, Yang (MSKCC); (Constellation); (Fudan); (Tsinghua)

    2011-08-29

    Histone methylation occurs on both lysine and arginine residues, and its dynamic regulation plays a critical role in chromatin biology. Here we identify the UHRF1 PHD finger (PHD{sub UHRF1}), an important regulator of DNA CpG methylation, as a histone H3 unmodified arginine 2 (H3R2) recognition modality. This conclusion is based on binding studies and cocrystal structures of PHD{sub UHRF1} bound to histone H3 peptides, where the guanidinium group of unmodified R2 forms an extensive intermolecular hydrogen bond network, with methylation of H3R2, but not H3K4 or H3K9, disrupting complex formation. We have identified direct target genes of UHRF1 from microarray and ChIP studies. Importantly, we show that UHRF1's ability to repress its direct target gene expression is dependent on PHD{sub UHRF1} binding to unmodified H3R2, thereby demonstrating the functional importance of this recognition event and supporting the potential for crosstalk between histone arginine methylation and UHRF1 function.

  19. Assessment Procedures of Norwegian PhD Theses as Viewed by Examiners from the USA, the UK and Sweden

    Science.gov (United States)

    Kyvik, Svein

    2014-01-01

    This article focuses on the assessment procedures of Norwegian PhD theses as viewed by external members of evaluation committees from three countries with different examination systems; the USA, the UK and Sweden. Their viewpoints give useful information not only on the pros and cons with the Norwegian system, but also on the strengths and…

  20. Now or Later?: An Empirical Investigation of When and Why Students Apply to Clinical Psychology PhD Programs

    Science.gov (United States)

    Zimak, Eric H.; Edwards, Katie M.; Johnson, Shannon M.; Suhr, Julie

    2011-01-01

    This study used a national sample of PhD students in clinical psychology (N = 1,034) to explore when students decided to pursue their graduate degree, reasons for their decisions, and associated satisfaction. Results indicated that immediately after completing their undergraduate degree, 57% of current graduate students reported postponing…

  1. Quality Indicators and Expected Outcomes for Social Work PhD Programs: Perceptions of Social Work Students, Faculty, and Administrators

    Science.gov (United States)

    Petr, Christopher G.; Harrington, Donna; Kim, Kyeongmo; Black, Beverly; Cunningham-Williams, Renee M.; Bentley, Kia J.

    2015-01-01

    This article presents and discusses the results of a national survey of social work PhD students, faculty, and administrators (n = 416), conducted by the Group for the Advancement of Doctoral Education in Social Work (GADE), in December 2012. The survey was undertaken to inform the updating of GADE's 2003 "Guidelines for Quality in Social…

  2. De-Colonising International Collaboration: The University of Kwazulu-Natal-Mauritius Institute of Education Cohort PhD Programme

    Science.gov (United States)

    Samuel, Michael Anthony; Mariaye, Hyleen

    2014-01-01

    This paper explores the setting up of the partnership across the Mauritian and South African higher education contexts with respect to the development of a postgraduate PhD doctoral studies programme. The Mauritian Institute of Education (MIE) aims to develop staffing capacities through engagement with doctoral studies, especially in the context…

  3. Trends in Ph.D. Productivity and Diversity in Top-50 U.S. Chemistry Departments: An Institutional Analysis

    Science.gov (United States)

    Laursen, Sandra L.; Weston, Timothy J.

    2014-01-01

    The education of doctoral chemists contributes to the chemical research enterprise and thus to innovation as an engine of the economy. This quantitative analysis describes trends in the production and diversity of chemistry Ph.D. degrees in the top-50 U.S. Ph.D.-granting departments in the past two decades. Time series data for individual…

  4. Multimodal Identity Texts as Mediational Spaces in Researching Ph.D. Students' Critical Teacher-Researcher Selves

    Science.gov (United States)

    Valencia, Marlon; Herath, Sreemali

    2015-01-01

    This paper analyses how two Ph.D. students used multimodal identity texts (MMITs) to document their research journeys as they engaged in their doctoral studies. Drawing on qualitative data collected from multiple pre-service teacher preparation programmes in Chile and Sri Lanka, two bi-national researchers (a Colombian-Canadian and a Sri…

  5. A Study on Changes of Supervision Model in Universities and Fostering Creative PhD Students in China

    DEFF Research Database (Denmark)

    Luo, Lingling; Zhou, Chunfang; Zhang, Song

    2015-01-01

    This paper aims to explore the changes of supervision model in higher education in relation to fostering creative Ph.D. students in China. The changes are being made from the traditional Apprentice Master Model (AMM) to the modern Collaborative Cohort Model (CCM). According to the results of the ...

  6. The "Academic" Qualities of Practice: What Are the Criteria for a Practice-based PhD?

    Science.gov (United States)

    Winter, Richard; Griffiths, Morwenna; Green, Kath

    2000-01-01

    A questionnaire to Ph.D. examiners across disciplines explored criteria appropriate for evaluating practice-based doctoral dissertations, in particular by collecting a core vocabulary of terms. Negative criteria included the lack of: intellectual grasp, coherence, engagement with the literature, originality, and generalizability, along with…

  7. Device interoperability and authentication for telemedical appliance based on the ISO/IEEE 11073 Personal Health Device (PHD) Standards.

    Science.gov (United States)

    Caranguian, Luther Paul R; Pancho-Festin, Susan; Sison, Luis G

    2012-01-01

    In this study, we focused on the interoperability and authentication of medical devices in the context of telemedical systems. A recent standard called the ISO/IEEE 11073 Personal Health Device (X73-PHD) Standards addresses the device interoperability problem by defining common protocols for agent (medical device) and manager (appliance) interface. The X73-PHD standard however has not addressed security and authentication of medical devices which is important in establishing integrity of a telemedical system. We have designed and implemented a security policy within the X73-PHD standards. The policy will enable device authentication using Asymmetric-Key Cryptography and the RSA algorithm as the digital signature scheme. We used two approaches for performing the digital signatures: direct software implementation and use of embedded security modules (ESM). The two approaches were evaluated and compared in terms of execution time and memory requirement. For the standard 2048-bit RSA, ESM calculates digital signatures only 12% of the total time for the direct implementation. Moreover, analysis shows that ESM offers more security advantage such as secure storage of keys compared to using direct implementation. Interoperability with other systems was verified by testing the system with LNI Healthlink, a manager software that implements the X73-PHD standard. Lastly, security analysis was done and the system's response to common attacks on authentication systems was analyzed and several measures were implemented to protect the system against them.

  8. Standard-compliant real-time transmission of ECGs: harmonization of ISO/IEEE 11073-PHD and SCP-ECG.

    Science.gov (United States)

    Trigo, Jesús D; Chiarugi, Franco; Alesanco, Alvaro; Martínez-Espronceda, Miguel; Chronaki, Catherine E; Escayola, Javier; Martínez, Ignacio; García, José

    2009-01-01

    Ambient assisted living and integrated care in an aging society is based on the vision of the lifelong Electronic Health Record calling for HealthCare Information Systems and medical device interoperability. For medical devices this aim can be achieved by the consistent implementation of harmonized international interoperability standards. The ISO/IEEE 11073 (x73) family of standards is a reference standard for medical device interoperability. In its Personal Health Device (PHD) version several devices have been included, but an ECG device specialization is not yet available. On the other hand, the SCP-ECG standard for short-term diagnostic ECGs (EN1064) has been recently approved as an international standard ISO/IEEE 11073-91064:2009. In this paper, the relationships between a proposed x73-PHD model for an ECG device and the fields of the SCP-ECG standard are investigated. A proof-of-concept implementation of the proposed x73-PHD ECG model is also presented, identifying open issues to be addressed by standards development for the wider interoperability adoption of x73-PHD standards.

  9. Kant en los problemas de filosofía de la mente contemporánea entre D. Davidson y J. Kim: un argumento a favor del Monismo Anómalo

    OpenAIRE

    Martínez Gómez, José Nicolás

    2016-01-01

    El Monismo Anómalo que Donald Davidson postuló como posible derrotero a propósito de los problemas latentes en filosofía de la mente contemporánea ha sido víctima de serias críticas, en especial aquellas planteadas por Jaegwon Kim. Sin embargo, una lectura que incluya las referencia que Davidson hizo del proyecto que Kant desarrolló en la Tercera Antinomia de la Razón Pura puede servir para ofrecer una lectura a favor de su proyecto.

  10. Kim Brandt, Kingdom of Beauty: Mingei and the Politics of Folk Art in Imperial Japan (Le royaume de la beauté : le Mingei et la politique de l’art populaire dans le Japon impérial

    OpenAIRE

    Sablé-Denans, Nadia

    2014-01-01

    L’exposition proposée par le Musée du quai Branly en 2008-2009 sur les objets et l’esthétique mingei a donné l’occasion de parcourir les derniers ouvrages parus sur le sujet. La monographie de Kim Brandt, professeure associée en histoire japonaise à l’Université Columbia, mérite sa place parmi ces lectures. Chronologiquement organisé, Kingdom of Beauty expose l’histoire du mouvement pour les Arts populaires de ses origines, dans les années 1920, à la fin de la Seconde Guerre mondiale, en lien...

  11. MS PHD'S: Bridging the Gap of Academic and Career Success Through Educational and Professional Development for Minorities

    Science.gov (United States)

    Brown, D.; Vargas, W.; Padilla, E.; Strickland, J.; Echols, E.; Johnson, A.; Williamson Whitney, V.; Ithier-Guzman, W.; Ricciardi, L.; Johnson, A.; Braxton, L.

    2011-12-01

    Historically, there has been a lack of ethnic and gender diversity in the geo-sciences. The Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science (MS PHD'S) Professional Development Program provides a bridge to young scientists of diverse backgrounds who in turn will impact many. In a process of 3 phases, the program introduces the students to the scientific community through participation in professional and society meetings and networking with scientists and personnel within federal agencies, academic institutions and STEM-based industries. The program builds confidence, offers role models for professional development and provides students support during their education. Upon completion, students achieve a high level of self-actualization and self-esteem combined with individual growth. They become part of a community that continuously provides support and security to each other. This support is tangible through the mentor/mentee relationships which will help with individual growth throughout the mentoring cycle. Having role models and familiar faces to whom mentees can relate to will encourage our students to succeed in the STEM's field. To date, 159 students have participated in the program: 26 have successfully completed their PhD and 56 are currently enrolled in the PhD programs nationwide. The MS PHD'S Program creates a forum of diverse peoples by diverse peoples with diverse interest and strength, where the ongoing goal is to continually raise the bar for each individual. MS PHD'S establishes a nurturing goal-oriented environment for the geo scientist of the future who in turn will make profound contributions on a local, national and global scale. To conclude, MSPHD'S not only bridges the gap of unrepresented minorities in STEM careers, but also generates educational approaches to make the earth system sciences available to more, impacting all.

  12. On Films Directed by Ki-duk Kim and Dual Cultural Context in Criticism%金基德电影及批评的二元文化语境

    Institute of Scientific and Technical Information of China (English)

    裴媛媛

    2015-01-01

    By adopting symbolic signs in his independent films, Ki-duk Kim combines mysteries in Eastern culture and rational reflection in Western culture. He aims at the western European market, and attempts to impose Eastern cultural elements to the Westerners, causing a wide range of criticism made by criticizers in his own country. By an analysis of the films directed by Ki-duk Kim, it is proposed that the dual cultural context makes it possible that people can expect the co-existence of multi-cultural elements.%金基德的独立电影通常采用符号化的象征手法,将东方文化的神性感知与西方文化的理性反思融合在一起。他立足于西欧市场,试图把东方文化元素贩卖到西方去,这看似一种国际视野,却惹来本土批论家的一片唏嘘。综观金基德的电影创作及批评接受,二元文化语境的双重叙事,为实现多元文化的通约共存,提供了一种理论预设和期待可能性。

  13. Addiction protein Phd of plasmid prophage P1 is a substrate of the ClpXP serine protease of Escherichia coli.

    OpenAIRE

    Lehnherr, H; Yarmolinsky, M B

    1995-01-01

    Plasmid-encoded addiction genes augment the apparent stability of various low copy number bacterial plasmids by selectively killing plasmid-free (cured) segregants or their progeny. The addiction module of plasmid prophage P1 consists of a pair of genes called phd and doc. Phd serves to prevent host death when the prophage is retained and, should retention mechanisms fail, Doc causes death on curing. Doc acts as a cell toxin to which Phd is an antidote. In this study we show that host mutants...

  14. Eberhard Widmann (Stefan Meyer Institute, Vienna) and Silke Federmann (Ph.D. Student from Vienna in the CERN-Austrian Ph.D. program) together with a microwave cavity developed by Silke at CERN. The cavity will be used for the first time to look for spin-flip transitions of antihydrogen atoms later this year.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    Eberhard Widmann (Stefan Meyer Institute, Vienna) and Silke Federmann (Ph.D. Student from Vienna in the CERN-Austrian Ph.D. program) together with a microwave cavity developed by Silke at CERN. The cavity will be used for the first time to look for spin-flip transitions of antihydrogen atoms later this year.

  15. Tracking Multiple Video Targets with an Improved GM-PHD Tracker

    Directory of Open Access Journals (Sweden)

    Xiaolong Zhou

    2015-12-01

    Full Text Available Tracking multiple moving targets from a video plays an important role in many vision-based robotic applications. In this paper, we propose an improved Gaussian mixture probability hypothesis density (GM-PHD tracker with weight penalization to effectively and accurately track multiple moving targets from a video. First, an entropy-based birth intensity estimation method is incorporated to eliminate the false positives caused by noisy video data. Then, a weight-penalized method with multi-feature fusion is proposed to accurately track the targets in close movement. For targets without occlusion, a weight matrix that contains all updated weights between the predicted target states and the measurements is constructed, and a simple, but effective method based on total weight and predicted target state is proposed to search the ambiguous weights in the weight matrix. The ambiguous weights are then penalized according to the fused target features that include spatial-colour appearance, histogram of oriented gradient and target area and further re-normalized to form a new weight matrix. With this new weight matrix, the tracker can correctly track the targets in close movement without occlusion. For targets with occlusion, a robust game-theoretical method is used. Finally, the experiments conducted on various video scenarios validate the effectiveness of the proposed penalization method and show the superior performance of our tracker over the state of the art.

  16. Tracking Multiple Video Targets with an Improved GM-PHD Tracker.

    Science.gov (United States)

    Zhou, Xiaolong; Yu, Hui; Liu, Honghai; Li, Youfu

    2015-12-03

    Tracking multiple moving targets from a video plays an important role in many vision-based robotic applications. In this paper, we propose an improved Gaussian mixture probability hypothesis density (GM-PHD) tracker with weight penalization to effectively and accurately track multiple moving targets from a video. First, an entropy-based birth intensity estimation method is incorporated to eliminate the false positives caused by noisy video data. Then, a weight-penalized method with multi-feature fusion is proposed to accurately track the targets in close movement. For targets without occlusion, a weight matrix that contains all updated weights between the predicted target states and the measurements is constructed, and a simple, but effective method based on total weight and predicted target state is proposed to search the ambiguous weights in the weight matrix. The ambiguous weights are then penalized according to the fused target features that include spatial-colour appearance, histogram of oriented gradient and target area and further re-normalized to form a new weight matrix. With this new weight matrix, the tracker can correctly track the targets in close movement without occlusion. For targets with occlusion, a robust game-theoretical method is used. Finally, the experiments conducted on various video scenarios validate the effectiveness of the proposed penalization method and show the superior performance of our tracker over the state of the art.

  17. A barley PHD finger transcription factor that confers male sterility by affecting tapetal development.

    Science.gov (United States)

    Fernández Gómez, José; Wilson, Zoe A

    2014-08-01

    Controlling pollen development is of major commercial importance in generating hybrid crops and selective breeding, but characterized genes for male sterility in crops are rare, with no current examples in barley. However, translation of knowledge from model species is now providing opportunities to understand and manipulate such processes in economically important crops. We have used information from regulatory networks in Arabidopsis to identify and functionally characterize a barley PHD transcription factor MALE STERTILITY1 (MS1), which expresses in the anther tapetum and plays a critical role during pollen development. Comparative analysis of Arabidopsis, rice and Brachypodium genomes was used to identify conserved regions in MS1 for primer design to amplify the barley MS1 gene; RACE-PCR was subsequently used to generate the full-length sequence. This gene shows anther-specific tapetal expression, between late tetrad stage and early microspore release. HvMS1 silencing and overexpression in barley resulted in male sterility. Additionally, HvMS1 cDNA, controlled by the native Arabidopsis MS1 promoter, successfully complemented the homozygous ms1 Arabidopsis mutant. These results confirm the conservation of MS1 function in higher plants and in particular in temperate cereals. This has provided the first example of a characterized male sterility gene in barley, which presents a valuable tool for the future control of male fertility in barley for hybrid development.

  18. ANALYSIS OF METHODICAL DEFECTS IN PHD AND DOCTORAL THESIS ON ECONOMICS

    Directory of Open Access Journals (Sweden)

    R. D. Gutgarts

    2016-01-01

    Full Text Available The aim of the article is to consider the most typical defectswhich can be found in PhD and doctoral dissertations on economic sciences. The research is based on a work experience of the author as the member of dissertation council, the reviewer and the opponent of dissertation works.Methods. The methods of the analysis, comparison, and generalization are used while researching the problem.Results and scientific novelty. The miscalculations and errors in master’s and doctoral dissertations on economics which have methodical nature and not depend on a specific subject of work are disclosed and systematized. In particular, the following questions concerning the process of work are studied out on specific examples: work with information sources, Internet resources; options of correct and incorrect use o tools of information technologies; applied problems of results of scientific research, etc.Practical significance of the publication consists, firstly, in recommendations of the author concerning leveling and elimination of common defects of dissertation works and scientific articles; secondly, in the proposal of the general and methodical plan for introduction of training standards in a postgraduate study.

  19. What Does It Take? Auto/biography as Performative PhD Thesis

    Directory of Open Access Journals (Sweden)

    Sally Berridge

    2008-05-01

    Full Text Available Recently I completed a performative (creative PhD in the School of Creative Communication (now the Faculty of Design and Creative Practice at the University of Canberra, Australia, where such doctorates were established only in 2002. Since I completed in 2006, I have been contemplating some process issues that emerged during my three and a half year's studies. While conferring with fellow students and colleagues at three universities in England, I found that the many of the problems they encountered were similar and so were not due uniquely to the innovative phase that I encountered, but were part of a wider scenario. At my university, the requirements for a creative doctorate are a creative component (equivalent to about 60,000 words and a theoretical component (exegesis of about 30,000 words. The physical outcome of my thesis is two artist's books: one, Tissue, is autobiographical, while questioning the nature of autobiography, memory and identity. The other, Re-Picturing My Life, is the theoretical component, examining several paradigms including issues of methodology; the value of art as research; theories of memory, identity, autobiography, and human interactions with objects. I have placed some of my text/images in this paper to provide a taste of the work in my thesis. My paper reflects on performative work in the context of academic research, and the resilience, determination and sense of humour needed to complete a doctorate successfully in this valuable area of endeavour. URN: urn:nbn:de:0114-fqs0802451

  20. Healing in forgiveness: A discussion with Amanda Lindhout and Katherine Porterfield, PhD

    Directory of Open Access Journals (Sweden)

    Katherine A. Porterfield

    2014-09-01

    Full Text Available In 2008, Amanda Lindhout was kidnapped by a group of extremists while traveling as a freelance journalist in Somalia. She and a colleague were held captive for more than 15 months, released only after their families paid a ransom. In this interview, Amanda discusses her experiences in captivity and her ongoing recovery from this experience with Katherine Porterfield, Ph.D. a clinical psychologist at the Bellevue/NYU Program for Survivors of Torture. Specifically, Amanda describes the childhood experiences that shaped her thirst for travel and knowledge, the conditions of her kidnapping, and her experiences after she was released from captivity. Amanda outlines the techniques that she employed to survive in the early aftermath of her capture, and how these coping strategies changed as her captivity lengthened. She reflects on her transition home, her recovery process, and her experiences with mental health professionals. Amanda's insights provide an example of resilience in the face of severe, extended trauma to researchers, clinicians, and survivors alike. The article ends with an discussion of the ways that Amanda's coping strategies and recovery process are consistent with existing resilience literature. Amanda's experiences as a hostage, her astonishing struggle for physical and mental survival, and her life after being freed are documented in her book, co-authored with Sara Corbett, A House in the Sky.

  1. Integrating emerging areas of nursing science into PhD programs.

    Science.gov (United States)

    Henly, Susan J; McCarthy, Donna O; Wyman, Jean F; Stone, Patricia W; Redeker, Nancy S; McCarthy, Ann Marie; Alt-White, Anna C; Dunbar-Jacob, Jacqueline; Titler, Marita G; Moore, Shirley M; Heitkemper, Margaret M; Conley, Yvette P

    2015-01-01

    The Council for the Advancement of Nursing Science aims to "facilitate and recognize life-long nursing science career development" as an important part of its mission. In light of fast-paced advances in science and technology that are inspiring new questions and methods of investigation in the health sciences, the Council for the Advancement of Nursing Science convened the Idea Festival for Nursing Science Education and appointed the Idea Festival Advisory Committee to stimulate dialogue about linking PhD education with a renewed vision for preparation of the next generation of nursing scientists. Building on the 2010 American Association of Colleges of Nursing Position Statement "The Research-Focused Doctoral Program in Nursing: Pathways to Excellence," Idea Festival Advisory Committee members focused on emerging areas of science and technology that impact the ability of research-focused doctoral programs to prepare graduates for competitive and sustained programs of nursing research using scientific advances in emerging areas of science and technology. The purpose of this article is to describe the educational and scientific contexts for the Idea Festival, which will serve as the foundation for recommendations for incorporating emerging areas of science and technology into research-focused doctoral programs in nursing. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Empirical Essays on the Labor Market Outcomes of PhD Graduates

    DEFF Research Database (Denmark)

    Pedersen, Heidi Skovgaard

    that PhDs accelerate growth. A major objective has been to direct more PhDs to the industry to use their skills to monetize knowledge. However, we have limited evidence on how PhDs are absorbed into the labor market, how the market values PhD labor, and how PhDs value the possibility to work...... in the private sector. The dissertation investigates determinants of labor market decisions among recent cohorts of PhDs in Denmark to assess how the increasing number of PhDs is absorbed into the economy. Based on econometric models, it examines what factors trigger individual career decisions and supply...... opportunities. The researcher career path has surely evolved as society’s visions for PhDs’ utility in the search for knowledge, and this has led to more diverse career paths. The dissertation sheds light on how career choices are formed in the current labor market structure that new PhDs encounter early...

  3. Improving Doctoral Success by Matching PhD Students with Supervisors

    Directory of Open Access Journals (Sweden)

    Antònia Darder

    2016-02-01

    Full Text Available A key aspect of the effective supervision of PhD research is the supervisor-student relationship. This interaction is affected by the characteristics and needs of students and institutional conditions, as well as the skills, attitudes, and roles of supervisors and their supervisory styles. When supervision is carried out at a distance, it entails an additional challenge, mainly concerning interaction. The purpose of this study is to improve the research process, supervision, and design of virtual environments in order to support this supervision. The study identifies the supervisory relationships that affect doctoral research conducted at a distance from the student’s academic institution. It also describes how students and their supervisors perceived the characteristics of supervision and the skills and attitudes students perceived in and expected from their supervisors. For data collection, semistructured interviews were used. The results indicate important differences between supervisors’ perceptions concerning their own role and students’ needs regarding supervision, and they demonstrate the importance of attending to student needs and, on the part of supervisors, exercising responsibility in the development of research competencies in students, as is the case of independence of criteria and autonomy.

  4. The postgraduate students’ (masters, PhD metaphors about education of statistic

    Directory of Open Access Journals (Sweden)

    Colak Serap

    2016-01-01

    Full Text Available Statistics is an important part of our life when it comes to economy, education, sport, politics and research. Research is a primary job for the ones pursuing academic career and statistics is one of the basic components of a research. Metaphor is used as an equivalent to figurative expression (‘mecaz’ in Turkish language. Study group is composed of 19 females (age 27.7 and 40 males (age 30.85 - 59 students in total. Demographic information of participants was collected. Participants were provided with questionnaire in order to assess their metaphorical creation whereby they were asked to fill in the sentence - “statistics is like/ similar to …, because…” - with metaphor. The study has collected total of 59 metaphors in 6 categories. The most created metaphor is in ‘discovering/ revealing’ category. 42.5% of Master’s students and 25% of PhD students are in this category. Metaphors created by graduate students are representing their views about statistics course and hence their view about importance of research. The category ‘discovering/ revealing’, the one with the most created metaphor of this study, is the main concept of science. Consequently, good knowledge of statistics is needed for graduate students to conduct research.

  5. Why undertake a pilot in a qualitative PhD study? Lessons learned to promote success.

    Science.gov (United States)

    Wray, Jane; Archibong, Uduak; Walton, Sean

    2017-01-23

    Background Pilot studies can play an important role in qualitative studies. Methodological and practical issues can be shaped and refined by undertaking pilots. Personal development and researchers' competence are enhanced and lessons learned can inform the development and quality of the main study. However, pilot studies are rarely published, despite their potential to improve knowledge and understanding of the research. Aim To present the main lessons learned from undertaking a pilot in a qualitative PhD study. Discussion This paper draws together lessons learned when undertaking a pilot as part of a qualitative research project. Important methodological and practical issues identified during the pilot study are discussed including access, recruitment, data collection and the personal development of the researcher. The resulting changes to the final study are also highlighted. Conclusion Sharing experiences of and lessons learned in a pilot study enhances personal development, improves researchers' confidence and competence, and contributes to the understanding of research. Implications for practice Pilots can be used effectively in qualitative studies to refine the final design, and provide the researcher with practical experience to enhance confidence and competence.

  6. Training in psychodiagnostic testing in APA-approved PsyD and PhD clinical psychology programs.

    Science.gov (United States)

    Piotrowski, C; Zalewski, C

    1993-10-01

    Fifty-one percent (N = 80) of directors of doctoral PhD and PsyD programs in clinical psychology, accredited by the American Psychological Association (APA), responded to a survey on assessment training. The study was a replication of an earlier survey by Piotrowski and Keller (1984b) on instruction, practices, and attitudes on testing. Our findings indicated that training emphasis in assessment coursework has changed very little over the past decade. Intelligence testing was emphasized in most programs, followed by objective and projective personality assessment. However, training in behavioral assessment techniques was required in only half of the responding programs. There were no significant differences between PhD and PsyD programs concerning required coursework in assessment. Factors that influence the perennial importance of testing in the clinical core curriculum are discussed.

  7. Training PhD Physicists for Industrial Careers: The Industrial Leadership in Physics Program at Georgetown University.

    Science.gov (United States)

    van Keuren, Edward

    2009-03-01

    The Physics department at Georgetown University has a unique PhD level graduate program designed to prepare PhD physicists for positions in high-tech business. Launched in 2001, the Industrial Leadership in Physics (ILP) graduate program combines training in technical subjects and business topics with a focus on group learning, communication skills, and practical work experience. Some highlights of the program include a modular curriculum in fundamental physics, centered on solid-state physics, instrumentation, problem solving and computer modeling; a year-long apprenticeship at the site of an industrial partner chosen to match the interests of the student and coursework in the McDonough School of Business at Georgetown. This presentation will give an overview of the program.

  8. Crystal structure of PHD domain of UHRF1 and insights into recognition of unmodified histone H3 arginine residue 2

    Institute of Scientific and Technical Information of China (English)

    Lulu Hu; Ze Li; Ping Wang; Yan Lin; Yanhui Xu

    2011-01-01

    Dear Editor,UHRF1 (ubiquitin-like,containing plant homeodomain (PHD) and RING finger domains,1),also known as ICBP90 in human and NP95 in mouse,is a critical regulator of maintenance of CpG DNA methylation through targeting de novo DNA methyltransferase (DNMT1) to hemimethylated replication forks;its ablation leads to genomic hypomethylation and cell cycle arrest [1,2].

  9. Supporting Education PhD and DEd Students to Become Confident Academic Writers: An Evaluation of Thesis Writers' Circles

    Science.gov (United States)

    Larcombe, Wendy; McCosker, Anthony; O'Loughlin, Kieran

    2007-01-01

    This paper critically evaluates the pilot of a Thesis Writers' Circles program offered to Education PhD and DEd students at the University of Melbourne in semester 2, 2005. The analysis focuses on the needs of those students that were felt to be well-met by this model of support. Broadly, the paper identifies two distinct but inter-related themes:…

  10. A biographical note on Max Friedrich (1856-1887), Wundt's first PhD student in experimental psychology.

    Science.gov (United States)

    Domanski, Cezary W

    2004-01-01

    This article unveils some previously unknown facts about the short life of Max Friedrich (1856-1887), the author in 1881 of the first PhD dissertation on experimental psychology, written under the supervision of Wilhelm Wundt: "On the Duration of Apperception for Simple and Complex Visual Stimuli." The article describes Friedrich's family background and life, professional career as a teacher, and works in psychology and mathematics.

  11. Simulation Programs for Ph.D. Study of Analysis, Modeling and Optimum Design of Solar Domestic Hot Water Systems

    DEFF Research Database (Denmark)

    Qin, Lin

    1999-01-01

    The design of solar domestic hot water system is a complex process, due to characteristics inherent in solar heating technology. Recently, computer simulation has become a widely used technique to improve the understanding of the thermal processes in such systems. This report presents the detailed...... programs or units that were developed in the Ph.D study of " Analysis, Modeling and Optimum Design of Solar Domestic Hot Water Systems"....

  12. Industrial Ph.D. Programs for the Strengthening of the Industry’s Production of Innovation in Colombia

    Directory of Open Access Journals (Sweden)

    Jorge Celis

    2016-09-01

    Full Text Available Today’s firms face a new global economy powered by knowledge rather than physical resources and natural raw materials. Universities are crucial actors in ensuring economic development, not only by training highly qualified human capital, but also by producing new knowledge with innovation potential. University–industry research collaborations (UICs have been increaingly recognized as an innovation mode. Highly qualified people, mainly at Ph.D. level, are fundamental for the increase of the knowledge pool from which firms and society as a whole can benefit in terms of the production of innovation. The demand for more specialized researchers in business/industry has led to new versions of doctoral programs, such as Industrial Ph.D. Programs (IPPs, which are well-established in a number of countries. After using an analytical international and comparative education methodology, we have found that the cooperation with industry to develop Ph.D. programs in Colombia is relatively weak and requires to be enhanced. In this paper, we argue for the alignment of the so-called third academic mission of economic development with the traditional academic missions of teaching and research through the implementation of IPPs as a mechanism for strengthening the innovation process of firms and country’s economic growth.

  13. Using Communicative Action Theory to Analyse Relationships Between Supervisors and Phd Students in a Technical University in Sweden

    Directory of Open Access Journals (Sweden)

    Michael Christie

    2013-04-01

    Full Text Available In this paper the authors use the theory of communicative action (Habermas, 1984-6 to analyse problematic relationships that can occur between supervisors and PhD students, between co-supervisors and between the students themselves. In a situation where power is distributed unequally, instrumental and strategic action on the part of either party can complicate and disturb efficacious relationships. We use Flanagan’s critical incident technique (Flanagan, 1954 to analyse twenty-five incidents that are told from a supervisor perspective and twentyfive from a PhD student perspective. The analysis reveals that a large proportion of incidents involved power struggles. Other categories include lack of professional or emotional support and poor communication. Rational dialogue based on Habermasian principles might have avoided many of these problems. The analysis concludes with some practical suggestions as to how the use of communicative action theory and critical incident technique can improve supervision, supervision training and the PhD process.

  14. Adaptive Measurement Partitioning Algorithm for a Gaussian Inverse Wishart PHD Filter that Tracks Closely Spaced Extended Targets

    Directory of Open Access Journals (Sweden)

    P. Li

    2017-06-01

    Full Text Available Use of the Gaussian inverse Wishart probability hypothesis density (GIW-PHD filter has demonstrated promise as an approach to track an unknown number of extended targets. However, when targets of various sizes are spaced closely together and performing maneuvers, estimation errors will occur because measurement partitioning algorithms fail to provide the correct partitions. Specifically, the sub-partitioning algorithm fails to handle cases in which targets are of different sizes, while other partitioning approaches are sensitive to target maneuvers. This paper presents an improved partitioning algorithm for a GIW-PHD filter in order to solve the above problems. The sub-partitioning algorithm is improved by considering target extension information and by employing Mahalanobis distances to distinguish among measurement cells of different sizes. Thus, the improved approach is not sensitive to either differences in target sizes or target maneuvering. Simulation results show that the use of the proposed partitioning approach can improve the tracking performance of a GIW-PHD filter when target are spaced closely together.

  15. QGIS TimeManager and how the QGIS community helped me make a great leap forward in visualizing tracking data for my PhD project

    DEFF Research Database (Denmark)

    Nielsen, Søren Zebitz

    2015-01-01

    This blog post is the story how collaboration with the QGIS developer community made me able to produce some much needed visualizations of pedestrian tracking data for my ongoing PhD project.......This blog post is the story how collaboration with the QGIS developer community made me able to produce some much needed visualizations of pedestrian tracking data for my ongoing PhD project....

  16. English summary of chapters in PhD Thesis 'Landscape transformations. A new paradigm for working with the synergy of physical and abstract landscapes

    DEFF Research Database (Denmark)

    Munck Petersen, Rikke

    2011-01-01

    English summary of chapters in PhD Thesis 'Landscape transformations. A new paradigm for working with the synergy of physical and abstract landscapes in relation to the ICAR-CORA Prize 2011......English summary of chapters in PhD Thesis 'Landscape transformations. A new paradigm for working with the synergy of physical and abstract landscapes in relation to the ICAR-CORA Prize 2011...

  17. Living in 'Sunny Woods'; Wohnen in Sunny Woods - Zuerich Hoengg

    Energy Technology Data Exchange (ETDEWEB)

    Naef, R.; Widmer, P.

    2003-07-01

    This final report for the Swiss Federal Office of Energy (SFOE) takes a look at the results of a study made on the energy-efficiency of an apartment house with six maisonette apartments built on a south-facing slope in Zurich, Switzerland. The report describes the construction and the building services installations of this zero-energy building which features buried conduits for air-preheating, individual solar-thermal and photovoltaic installations and air/water heat pumps. The performance of these installations is commented on and differences in performance between individual apartments are examined. The architectural design of the building, which won both Swiss and European solar prizes, is described and commented on. The monitoring systems employed and the results obtained for the various components of the building technical services including vacuum solar collectors and thin-film photovoltaics are presented and commented on.

  18. Objectives and Assessment of the NMSU Physics Ph.D. program

    Science.gov (United States)

    Zollner, Stefan

    2012-03-01

    New Mexico State University (NMSU) in Las Cruces, NM, is accredited by the Higher Learning Commission (HLC) and a member of the North Central Association of Colleges and Schools (NCA). As part of our continuous accreditation, the physics department annually assesses its progress towards goals and objectives. Our academic goals include the development of skills pertinent to solving advanced problems in physics, a mastery of advanced concepts in physics, an in-depth knowledge of one or more subfields, and develop the ability to conduct original research in a specialization. These goals are supported by objectives, including scientific expertise, advanced training, experimental training, communication skills, and technical know-how. We measure one direct student learning outcome, the ability to solve advanced problems in general physics subjects. The instrument for this measurement is our written physics comprehensive (Ph.D. candidacy) exam, which is administered by an examination committee consisting of all faculty members. We report annually on the percentage of students passing the exam in the various areas (QM, mechanics, E&M, Stat. Mech.). Ineffective preparation of our students in one area would show up by unusually low scores in that area. Since the problems are written and graded by all faculty (not just by those who taught the class), this provides an independent assessment of student learning and also evidence by other professionals skilled in the field. Our examinations are similar to published exams at other institutions. The results of the exam provide feedback to the course instructors, to the students, and to the department head who schedules instructors and courses. In some cases, retaking a course has been a condition of passing the exam for a student. (I acknowledge the efforts of Gary Kyle, who has managed our assessment for many years, and of the entire NMSU physics faculty for contributing to this process.)

  19. Main Tendencies in Preparing PhD Dissertations in Social Sciences and Humanities in Turkey

    Directory of Open Access Journals (Sweden)

    Yusuf Alpaydın

    2014-12-01

    Full Text Available Turkish doctorate programs are mainly composed of course work, preliminary examination, and dissertation stages. In these stages, naturally, several traditions and approaches are followed in different universities and graduate institutes. In this study, it is aimed to identify the main tendencies in preparing PhD dissertations in humanities and social sciences and to analyze the current situation in terms of production of academic knowledge and academic institutionalization in Turkey. Towards, the preparation processes for preliminary examinations and their contents, the procedures for the selection of advisors, dissertation subjects and research methodologies, and rationale for the study subjects, preference of research methodologies and academic writing techniques, and lastly relations with advisors and dissertation committee members are chosen for investigation. Quantitative methodology and survey technique has been used in the study to reach people who have completed their doctoral study on humanities and social sciences in 2011, 2012 and 2013 years in ten Turkish Universities that have given most doctoral graduates in social sciences. 405 people have responded the questionnaire form. The results indicate that the main motive behind selecting dissertation topics is related to career advancement, i.e securing a good position within the university system. Study found that systematic literature review is the most used research methodology and the reading-noting of all related sources than starting to write according to the materials is the most used academic writing technique in dis- sertations. Also, it is found that 1/3 of the participants had no chance to choose his/her advisors. Most of them perceived their relationship with their advisors positively, while admitting that the rate of advisors who actively contributed to the writing process is only 45 %.

  20. An interview with Robert S. Lane, Ph.D. Interviewed by Vicki Glaser.

    Science.gov (United States)

    Lane, Robert S

    2010-03-01

    Dr. Robert Lane received a B.A. degree in psychology from the University of California at Berkeley (UCB), an M.A. degree in biology at San Francisco State College, and a Ph.D. in entomology at UCB. While employed as a California State public health biologist he began his long-standing studies of the biology of ticks and the ecology and epidemiology of tick-borne disease agents. In 1984, Dr. Lane joined the faculty of UCB as a medical entomologist, a position he has held until the present. The diseases he and his many co-workers have investigated include Colorado tick fever, human granulocytic anaplasmosis, relapsing fever, Rocky Mountain spotted fever, tularemia, and particularly Lyme disease. Findings from these studies have elucidated the basic transmission cycles of and risk factors for spotted fever-group rickettsiae and Lyme disease spirochetes in the far western United States. Bob is a Fellow of both the California Academy of Sciences and the American Association for the Advancement of Science, a recipient of a UCB Biology Faculty Research Award and the C.W. Woodworth Award from the Pacific Branch of the Entomological Society of America, and a member of the Council for the International Congresses of Entomology. Also, he has served as president of the Acarological Society of America, the International Northwestern Conference on Diseases in Nature Communicable to Man, the Northern California Parasitologists, and the Society for Vector Ecology, as well as the Chair of Section D (Medical/Veterinary Entomology), Entomological Society.

  1. The significance of urine microscopy and urinary kidney injury molecular 1 and neutrophil gelatinase associated lipocalin in patients with primary kidney disease complicated with acute tubular interstitial lesion%尿沉渣联合尿KIM-1、NGAL在诊断原发性肾脏病合并急性肾小管间质病变中的意义

    Institute of Scientific and Technical Information of China (English)

    刘亚红; 苑丽华

    2015-01-01

    目的 观察原发性慢性肾脏病(CKD)合并急性肾小管间质病变(ATIL)时尿沉渣积分情况和尿肾损伤因子1(KIM-1)、中性粒细胞明胶酶相关脂质运载蛋白(NGAL)水平的变化,以期早期、准确发现ATIL.方法 经临床和病理确诊为CKD并发ATIL病例52例,对照组为无急性肾损伤(AKI)的原发性CKD患者33例,15例健康人为正常对照组.比较三组尿KIM-1、NGAL水平与尿沉渣积分的不同.结果 ①三组的尿KIM-1、NGAL水平和尿沉渣积分相比较,原发性CKD并发ATIL患者均高于其他两组(P<0.05),无AKI的CKD患者高于健康对照组(P<0.05);②尿KIM-1、NGAL水平与尿沉渣评分呈正相关(r=0.711,0.683,P<0.05),三者又均与CKD患者的ATIL严重程度呈正相关(r=0.892,0.735,0.745,P<0.05);③N-乙酰-β-D-氨基葡萄糖苷酶(NAG)、视黄醇结合蛋白(RBP)和α1-微球蛋白(α1-MG)尚在正常范围的患者尿KIM-1、NGAL水平已有升高,肾脏组织病理证实存在不同程度的ATIL;④尿KIM-1、NGAL、光抑素C(CysC)、NAG诊断ATIL的ROC曲线下面积大于尿RBP、α1-MG.尿沉渣诊断ATIL的受试者工作(ROC)曲线下面积为84%.尿KIM-1、NGAL联合尿沉渣积分诊断ATIL的准确性达100%.结论 尿沉渣联合尿KIM-1、NGAL可作为诊断原发性CKD并发ATIL的早期、无创、敏感的指标.%Objectives We explored urinary sediment scoring on the basis of the number of renal tubular epithelial cells and granular casts and the urinary level of KIM-1 and NGAL in patients with primary and chronic kidney disease (CKD) complicated with acute tubular interstitial lesion(ATIL),in order to find tubular interstitial injury early and accurately.Methods Data of 52 cases of primary CKD with ATIL and of 33 cases of CKD without acute kidney injury (AKI)admitted to Second Affiliated Hospital of Xingtai Medical College from February 2012 to February 2013 were analyzed.Urinary sediment scoring on the basis of the number of renal tubular epithelial

  2. A cross-language study on citation practice in PhD theses

    Directory of Open Access Journals (Sweden)

    Carmen Soler Monreal

    2011-12-01

    Full Text Available Citation practice provides justification for arguments and allows a writer to indicate a rhetorical gap for her/his research and adopt a tone of authority. Claims must be supported with evidence, and writers must demonstrate an understanding of approaches and knowledge in their fields of specialisation, in order to persuade the examiners that the thesis is worthy of the award of a doctorate (Thompson, 2005b. Candidates need to keep the adequate interpersonal relationship with the immediate audience (the examiners. They have to evaluate the previous research in an area of study and to be respectful with previous claims from authorities in the disciplines. They also need to position themselves in relation to other disciplinary members and highlight their individual claims. This paper investigates contrastively how interactional resources of citation and, in particular reporting verbs, are deployed in the literature review chapters of PhD theses written in English and in Spanish.El uso de citas y referencias proporciona una justificación para la argumentaci��n y permite al académico identificar un hueco o espacio retórico donde situar su investigación y adoptar cierto tono de autoridad. Las hipótesis o afirmaciones científicas deben apoyarse en evidencias, y los investigadores deben demostrar un buen conocimiento de los enfoques de su campo de especialización, para así persuadir a los miembros del tribunal examinador de la tesis de que ésta es digna de merecer el doctorado (Thompson, 2005b. Los doctorandos necesitan mantener una relación interpersonal apropiada con su audiencia (el tribunal examinador. Asimismo, necesitan evaluar la literatura de su área de estudio y ser respetuosos con las afirmaciones sobre investigaciones previas de autoridades de la disciplina. Necesitan adoptar una postura ante los miembros de la comunidad científica a la vez que enfatizan sus propias afirmaciones. En este trabajo se lleva a cabo un estudio

  3. Career Outcomes for Astronomy Ph.D. Graduates of the University of Texas at Austin: The Next Generation

    Science.gov (United States)

    Dinerstein, Harriet L.

    2011-01-01

    Sixteen years ago I conducted a survey of the career trajectories and outcomes of 78 individuals who earned Ph.D.s from the Department of Astronomy at the University of Texas at Austin during the period 1984-1995 (Dinerstein, H. 1996, AAS, 189.0501). In the current poster I extend these statistics up to the present, adding 68 Ph.D. recipients from 1996-2010. This is a sufficiently large sample to search for secular trends such as possible changes in duration of the postdoctoral stage, redistribution of demographics among different kinds of long-term positions, and the emergence of new categories of astronomy-related employment. The picture is less discouraging than one might expect. As of 2010, about 75% of the Texas graduates 7 - 14 years past the Ph.D. are still doing astronomy, and most of those in non-astronomical careers left the field by choice (and often have had considerable success in their alternate careers). Of those 6 years or less past the Ph.D., 50% were in postdoctoral positions and less than 10% had left astronomy. Recent reconsiderations of the employment market (Metcalfe, T.S. 2008, PASP, 120, 229; Seth, A. 2009, Astro2010: The Astronomy and Astrophysics Decadal Survey, Position Paper No. 51) make the point that a typical astronomer who ultimately achieves a permanent position will have held two or three prior temporary positions; this was equally true three decades ago. There has been notable growth nationwide in the number of astronomers employed as faculty at small liberal arts colleges and other undergraduate-centered institutions, a trend that to some degree was anticipated by the University of Texas cohort, which included a number of students for whom this was their personal goal. In a world where job certainty is no longer so prevalent, motivated and resourceful astronomers are finding ways to remain active members of our community.

  4. MS PHD'S: A Successful Model Promoting Inclusion, Preparation and Engagement of Underrepresented Minorities within the Geosciences Workforce

    Science.gov (United States)

    Padilla, E.; Scott, O.; Strickland, J. T.; Ricciardi, L.; Guzman, W. I.; Braxton, L.; Williamson, V.; Johnson, A.

    2015-12-01

    According to 2014 findings of the National Research Council, geoscience and related industries indicate an anticipated 48,000 blue-collar, scientific, and managerial positions to be filled by underrepresented minority (URM) workers in the next 15 years. An Information Handling Services (IHS) report prepared for the American Petroleum Institute forecasts even greater numbers estimating upward of 408,000 opportunities for URM workers related to growth in accelerated development of oil, gas and petroleum industries. However, many URM students lack the training in both the hard sciences and craft skills necessary to fill these positions. The Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science (MS PHD'S) Professional Development Program uses integrative and holistic strategies to better prepare URM students for entry into all levels of the geoscience workforce. Through a three-phase program of mentoring, community building, networking and professional development activities, MS PHD'S promotes collaboration, critical thinking, and soft skills development for participants. Program activities expose URM students to education, training and real-life geoscience workforce experiences while maintaining a continuity of supportive mentoring and training networks via an active virtual community. MS PHD'S participants report increased self-confidence and self-efficacy in pursuing geoscience workforce goals. To date, the program supports 223 participants of who 57, 21 and 16 have received Doctorate, Masters and Baccalaureate degrees respectively and are currently employed within the geoscience and related industries workforce. The remaining 129 participants are enrolled in undergraduate and graduate programs throughout the U.S. Geographic representation of participants includes 35 states, the District of Columbia, Puerto Rico and two international postdoctoral appointments - one in Saudi Arabia and the other in France.

  5. What makes good science? Information literacy seminars as a means to stimulate reflection among PhD students

    OpenAIRE

    Andreassen, Helene N.; Østvand, Lene

    2016-01-01

    Conference: Creating Knowledge VIII Organizers: NordINFOLIT Reykjavík, 2.-3. June 2016 In addition to the demanding task of writing a thesis, PhD students face the challenge of balancing the roles as “good scientists” and “good academics”, which in some cases might conflict (Carter, 2015). They are expected to carry out a laborious research project where they are responsible for keeping in line with the norms and values of research ethics, all while building the foundation for their ...

  6. For the greater good of science: The place of research data in information literacy teaching for PhD students

    OpenAIRE

    Andreassen, Helene N.; Østvand, Lene

    2016-01-01

    Presentation held at the European Conference on Information Literacy (ECIL). Arranged by Hacettepe University, Zagreb University, & ALCU. Held in Praha, 10.10.16 - 13.10.16. In addition to the demanding task of writing a thesis, PhD students face the challenge of balancing the roles as “good scientists” and “good academics”, which in some cases might conflict (Carter, 2015). They are expected to carry out a laborious research project where they are responsible for keeping in line with the ...

  7. Intrinsic product polarization and branch ratio in the S(1D, 3P)+HD reaction on three electronic states

    Science.gov (United States)

    Li, Lin; Dong, Shunle

    2016-09-01

    The intrinsic product polarization and intramolecular isotope effect of the S(1D, 3P)+HD reaction have been investigated on both the lowest singlet state (1A‧) and the triplet state (3A‧ and 3A″) potential energy surfaces by using quasi-classical trajectory and quantum mechanical methods. The calculations indicate that intramolecular isotope effects are different on the three electronic states. The stereodynamics study shows that the P(θr) distributions, P(ϕr) distributions, and polarization-dependent differential cross sections (PDDCSs) (00) are sensitive to mass factor and the product angular momentum vectors are not only aligned but also oriented.

  8. Research And Development For Capacity Building In TVET: The International PhD Programme Between UTHM And ITB Germany

    Directory of Open Access Journals (Sweden)

    Jailani M.Y.

    2009-08-01

    Full Text Available The Ninth Malaysia Plan, which is one step on the way to achieve Vision 2020, features a separate section on Technical and Vocational Education and Training (TVET. It assigns responsibilities for TVET teacher education at the various levels to specific institutions such as polytechnics and community colleges. Malaysia will also face significant challenge as the country is set to become industrialized. Strategic knowledge and skill have to be the basic form of capital to position Malaysia towards industrialization. The education system especially in TVET must yield K-workers to push Malaysia into the K-economy. The Malaysian government has been dedicated to reform the education system and to place Malaysia into a world-class education hub. One critical strategy taken by the government is to implement the National Dual Training System (NDTS. Universiti Tun Hussein Onn Malaysia (UTHM has been the key institution that strives to fulfil the national objective. UTHM offers and supply qualified TVET professionals at the academic levels of Bachelor, Master, and PhD programme to enrich the human capital of the nation. Due to the active international involvement and excellence recognition of UTHM as a TVET provider, a cross country research project involving UTHM from Malaysia, Universitat Autonoma de Barcelona (UAB from Spain, The Institute Technik und Bildung (ITB, Universität Bremen from Germany and Vocational Education Development Centre (VEDC Malang, Universitas Pendidikan Indonesia (UPI Bandung and Technical Education Development Centre (TEDC Bandung from Indonesia has agreed to partnership cooperation on a research project funded by the European Union Asia Link project headed by ITB. The research is focus on the development of trans-national standards of teacher training, their accreditation as well as the development of curricula. To strengthen the international collaboration, UTHM has taken an innovative initiative to work closely with the

  9. The experience of international nursing students studying for a PhD in the U.K: A qualitative study

    Science.gov (United States)

    2011-01-01

    Background Educating nurses to doctoral level is an important means of developing nursing capacity globally. There is an international shortage of doctoral nursing programmes, hence many nurses seek their doctorates overseas. The UK is a key provider of doctoral education for international nursing students, however, very little is known about international doctoral nursing students' learning experiences during their doctoral study. This paper reports on a national study that sought to investigate the learning expectations and experiences of overseas doctoral nursing students in the UK. Methods Semi-structured qualitative interviews were conducted in 2008/09 with 17 international doctoral nursing students representing 9 different countries from 6 different UK universities. Data were analysed thematically. All 17 interviewees were enrolled on 'traditional' 3 year PhD programmes and the majority (15/17) planned to work in higher education institutions back in their home country upon graduation. Results Studying for a UK PhD involved a number of significant transitions, including adjusting to a new country/culture, to new pedagogical approaches and, in some cases, to learning in a second language. Many students had expected a more structured programme of study, with a stronger emphasis on professional nursing issues as well as research - akin to the professional doctorate. Students did not always feel well integrated into their department's wider research environment, and wanted more opportunities to network with their UK peers. A good supervision relationship was perceived as the most critical element of support in a doctoral programme, but good relationships were sometimes difficult to attain due to differences in student/supervisor expectations and in approaches to supervision. The PhD was perceived as a difficult and stressful journey, but those nearing the end reflected positively on it as a life changing experience in which they had developed key professional and

  10. Simulation programs for ph.D. study of analysis, modeling and optimum design of solar domestic hot water systems

    Energy Technology Data Exchange (ETDEWEB)

    Lin Qin

    1998-12-31

    The design of solar domestic hot water (DHW) systems is a complex process, due to characteristics inherent in the solar heating technology. Recently, computer simulation has become a widely used technique to improve the understanding of the thermal processes in such systems. One of the main objects of the Ph.D. study of `Analysis, Modelling and optimum Design of Solar Domestic Hot Water Systems` is to develop and verify programs for carrying out the simulation and evaluation of the dynamic performance of solar DHW systems. During this study, simulation programs for hot water distribution networks and for certain types of solar DHW systems were developed. (au)

  11. Identifying most important skills for PhD students in Food Science and Technology: a comparison between industry and academic stakeholders

    Directory of Open Access Journals (Sweden)

    Chelo González-Martínez

    2015-10-01

    Full Text Available Nowadays, there is an increasing need of new skills for PhD students to face the future labour market prospects. PhD graduates must have qualities attractive not only in academia but also outside, in both manufacture and service-oriented enterprises, in small innovative companies, and in the civil services and public administration, among others. To know what the needs of these future employees are, is of great importance to be able to improve their personal and academic formation. The aim of this work was, in the framework of the EC-funded ISEKI_Food 4 network, to evaluate the most desirable specific and soft skills that PhD students should acquire by the end of their doctoral studies. To this aim, several surveys were conducted and sent to the different stakeholders (academia and food industry partners in order to collect the information needed. Results showed that competences related to research skills and techniques, research management, personal effectiveness and communication skills were considered to be the most valuable skills to be acquired by our PhD students to meet the future needs of the labour market.  The importance of these skills was appreciated differently, depending on the stakeholder. To sum up, some recommendations to integrate such valuable skills into the curricula of the PhD student are given.

  12. Pro Isomerization in MLL1 PHD3-Bromo Cassette Connects H3K4me Readout to CyP33 and HDAC-Mediated Repression

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Zhanxin; Song, Jikui; Milne, Thomas A.; Wang, Gang G.; Li, Haitao; Allis, C. David; Patel, Dinshaw J. (MSKCC); (Rockefeller)

    2010-09-13

    The MLL1 gene is a frequent target for recurrent chromosomal translocations, resulting in transformation of hematopoietic precursors into leukemia stem cells. Here, we report on structure-function studies that elucidate molecular events in MLL1 binding of histone H3K4me3/2 marks and recruitment of the cyclophilin CyP33. CyP33 contains a PPIase and a RRM domain and regulates MLL1 function through HDAC recruitment. We find that the PPIase domain of CyP33 regulates the conformation of MLL1 through proline isomerization within the PHD3-Bromo linker, thereby disrupting the PHD3-Bromo interface and facilitating binding of the MLL1-PHD3 domain to the CyP33-RRM domain. H3K4me3/2 and CyP33-RRM target different surfaces of MLL1-PHD3 and can bind simultaneously to form a ternary complex. Furthermore, the MLL1-CyP33 interaction is required for repression of HOXA9 and HOXC8 genes in vivo. Our results highlight the role of PHD3-Bromo cassette as a regulatory platform, orchestrating MLL1 binding of H3K4me3/2 marks and cyclophilin-mediated repression through HDAC recruitment.

  13. The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers.

    Science.gov (United States)

    Klein, Brianna J; Piao, Lianhua; Xi, Yuanxin; Rincon-Arano, Hector; Rothbart, Scott B; Peng, Danni; Wen, Hong; Larson, Connie; Zhang, Xi; Zheng, Xia; Cortazar, Michael A; Peña, Pedro V; Mangan, Anthony; Bentley, David L; Strahl, Brian D; Groudine, Mark; Li, Wei; Shi, Xiaobing; Kutateladze, Tatiana G

    2014-01-30

    The histone lysine demethylase KDM5B regulates gene transcription and cell differentiation and is implicated in carcinogenesis. It contains multiple conserved chromatin-associated domains, including three PHD fingers of unknown function. Here, we show that the first and third, but not the second, PHD fingers of KDM5B possess histone binding activities. The PHD1 finger is highly specific for unmodified histone H3 (H3K4me0), whereas the PHD3 finger shows preference for the trimethylated histone mark H3K4me3. RNA-seq analysis indicates that KDM5B functions as a transcriptional repressor for genes involved in inflammatory responses, cell proliferation, adhesion, and migration. Biochemical analysis reveals that KDM5B associates with components of the nucleosome remodeling and deacetylase (NuRD) complex and may cooperate with the histone deacetylase 1 (HDAC1) in gene repression. KDM5B is downregulated in triple-negative breast cancer relative to estrogen-receptor-positive breast cancer. Overexpression of KDM5B in the MDA-MB 231 breast cancer cells suppresses cell migration and invasion, and the PHD1-H3K4me0 interaction is essential for inhibiting migration. These findings highlight tumor-suppressive functions of KDM5B in triple-negative breast cancer cells and suggest a multivalent mechanism for KDM5B-mediated transcriptional regulation. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  14. The Histone-H3K4-Specific Demethylase KDM5B Binds to Its Substrate and Product through Distinct PHD Fingers

    Directory of Open Access Journals (Sweden)

    Brianna J. Klein

    2014-01-01

    Full Text Available The histone lysine demethylase KDM5B regulates gene transcription and cell differentiation and is implicated in carcinogenesis. It contains multiple conserved chromatin-associated domains, including three PHD fingers of unknown function. Here, we show that the first and third, but not the second, PHD fingers of KDM5B possess histone binding activities. The PHD1 finger is highly specific for unmodified histone H3 (H3K4me0, whereas the PHD3 finger shows preference for the trimethylated histone mark H3K4me3. RNA-seq analysis indicates that KDM5B functions as a transcriptional repressor for genes involved in inflammatory responses, cell proliferation, adhesion, and migration. Biochemical analysis reveals that KDM5B associates with components of the nucleosome remodeling and deacetylase (NuRD complex and may cooperate with the histone deacetylase 1 (HDAC1 in gene repression. KDM5B is downregulated in triple-negative breast cancer relative to estrogen-receptor-positive breast cancer. Overexpression of KDM5B in the MDA-MB 231 breast cancer cells suppresses cell migration and invasion, and the PHD1-H3K4me0 interaction is essential for inhibiting migration. These findings highlight tumor-suppressive functions of KDM5B in triple-negative breast cancer cells and suggest a multivalent mechanism for KDM5B-mediated transcriptional regulation.

  15. Arabidopsis MALE STERILITY1 encodes a PHD-type transcription factor and regulates pollen and tapetum development.

    Science.gov (United States)

    Ito, Takuya; Nagata, Noriko; Yoshiba, Yoshu; Ohme-Takagi, Masaru; Ma, Hong; Shinozaki, Kazuo

    2007-11-01

    The Arabidopsis thaliana MALE STERILITY1 (MS1) gene encodes a nuclear protein with Leu zipper-like and PHD-finger motifs and is important for postmeiotic pollen development. Here, we examined MS1 function using both cell biological and molecular biological approaches. We introduced a fusion construct of MS1 and a transcriptional repression domain (MS1-SRDX) into wild-type Arabidopsis, and the transgenic plants showed a semisterile phenotype similar to that of ms1. Since the repression domain can convert various kinds of transcriptional activators to dominant repressors, this suggested that MS1 functioned as a transcriptional activator. The Leu zipper-like region and the PHD motif were required for the MS1 function. Phenotypic analysis of the ms1 mutant and the MS1-SRDX transgenic Arabidopsis indicated that MS1 was involved in formation of pollen exine and pollen cytosolic components as well as tapetum development. Next, we searched for MS1 downstream genes by analyzing publicly available microarray data and identified 95 genes affected by MS1. Using a transgenic ms1 plant showing dexamethasone-inducible recovery of fertility, we further examined whether these genes were immediately downstream of MS1. From these results, we discuss a role of MS1 in pollen and tapetum development and the conservation of MS1 function in flowering plants.

  16. Novel perspectives on the PHD-HIF oxygen sensing pathway in cardioprotection mediated by IPC and RIPC

    Directory of Open Access Journals (Sweden)

    Silvia eMartin-Puig

    2015-05-01

    Full Text Available Reperfusion of ischemic cardiac tissue is the standard treatment for improving clinical outcome following myocardial infarction but is inevitably associated with ischemia-reperfusion injury (IRI. Ischemic myocardial injury can be alleviated by exposing the heart to brief episodes of sublethal ischemia-reperfusion prior to the ischemic insult, a phenomenon that has been termed ischemic preconditioning (IPC. Similarly, remote IPC (RIPC is defined as transient episodes of ischemia at a distant site before a subsequent prolonged injury of the target organ. In this setting, adaptive responses to hypoxia/ischemia in peripheral tissues include the release of soluble factors that have the potential to protect cardiomyocytes remotely. Oxygen fluctuation is a hallmark of insufficient tissue perfusion and ischemic episodes. Emerging evidence indicates that prolyl hydroxylase oxygen sensors (PHDs and hypoxia-inducible transcription factors (HIFs are critical regulators of IPC and RIPC. In this minireview, we discuss recent findings concerning the role of the PHD-HIF axis in IPC and RIPC-mediated cardioprotection and examine molecular pathways and cell types that might be involved. We also appraise the therapeutic value of targeting the PHD-HIF axis to enhance cardiac tolerance against IRI.

  17. Too Many PhD Graduates or Too Few Academic Job Openings: The Basic Reproductive Number R0 in Academia.

    Science.gov (United States)

    Larson, Richard C; Ghaffarzadegan, Navid; Xue, Yi

    2014-01-01

    The academic job market has become increasingly competitive for PhD graduates. In this note, we ask the basic question of 'Are we producing more PhDs than needed?' We take a systems approach and offer a 'birth rate' perspective: professors graduate PhDs who later become professors themselves, an analogue to how a population grows. We show that the reproduction rate in academia is very high. For example, in engineering, a professor in the US graduates 7.8 new PhDs during his/her whole career on average, and only one of these graduates can replace the professor's position. This implies that in a steady state, only 12.8% of PhD graduates can attain academic positions in the USA. The key insight is that the system in many places is saturated, far beyond capacity to absorb new PhDs in academia at the rates that they are being produced. Based on the analysis, we discuss policy implications.

  18. Integrating clinical medicine into biomedical graduate education to promote translational research: strategies from two new PhD programs.

    Science.gov (United States)

    Smith, Carolyn L; Jarrett, Marcia; Bierer, S Beth

    2013-01-01

    For several decades, a barrier has existed between research and clinical medicine, making it difficult for aspiring scientists to gain exposure to human pathophysiology and access to clinical/translational research mentors during their graduate training. In 2005, the Howard Hughes Medical Institute announced the Med Into Grad initiative to support graduate programs that integrate clinical knowledge into PhD biomedical training, with the goal of preparing a new cadre of translational researchers to work at the interface of the basic sciences and clinical medicine. Two institutions, Baylor College of Medicine and the Cleveland Clinic/Case Western Reserve University, developed new PhD programs in translational biology and/or molecular medicine. These programs teach the topics and skills that today's translational researchers must learn and expose students to clinical medicine. In this article, the authors compare and contrast the history, implementation, and evaluation of the Translational Biology and Molecular Medicine program at Baylor College of Medicine and the Molecular Medicine program at the Cleveland Clinic/Case Western Reserve University. The authors also demonstrate the feasibility of creating a multidisciplinary graduate program in molecular medicine that integrates pathophysiology and clinical medicine without extending training time. They conclude with a discussion of the similarities in training approaches that exist despite the fact that each program was independently developed and offer observations that emerged during their collaboration that may benefit others who are considering developing similar programs.

  19. Oral biology in middle age: a history of the University at Buffalo Oral Biology PhD Program.

    Science.gov (United States)

    Scannapieco, F A

    2014-05-01

    In 1960, the first Department of Oral Biology in the United States dedicated to the conduct of research, graduate biomedical research education, and the provision of basic oral science education for the DDS curriculum was established at the University at Buffalo. In 1963, the Department organized the first PhD Program in Oral Biology in the United States. This PhD program has produced a large cadre of oral health researchers, many of whom have gone on to make major contributions to dental research and education. This article provides a brief history of the program, the context within which the program was organized and developed, and a description of some of the many faculty, students, and fellows associated with the program. Additionally, to celebrate the 50th anniversary of this program, a symposium, entitled "The Oral Microbiome, Immunity and Chronic Disease", was held on June 12-14, 2013, in Buffalo, New York. The proceedings are published online in Advances in Dental Research (2014, Vol. 26).

  20. Novel perspectives on the PHD-HIF oxygen sensing pathway in cardioprotection mediated by IPC and RIPC.

    Science.gov (United States)

    Martin-Puig, Silvia; Tello, Daniel; Aragonés, Julián

    2015-01-01

    Reperfusion of ischemic cardiac tissue is the standard treatment for improving clinical outcome following myocardial infarction but is inevitably associated with ischemia-reperfusion injury (IRI). Ischemic myocardial injury can be alleviated by exposing the heart to brief episodes of sublethal ischemia-reperfusion prior to the ischemic insult, a phenomenon that has been termed ischemic preconditioning (IPC). Similarly, remote IPC (RIPC) is defined as transient episodes of ischemia at a distant site before a subsequent prolonged injury of the target organ. In this setting, adaptive responses to hypoxia/ischemia in peripheral tissues include the release of soluble factors that have the potential to protect cardiomyocytes remotely. Oxygen fluctuations is a hallmark of insufficient tissue perfusion and ischemic episodes. Emerging evidence indicates that prolyl hydroxylase oxygen sensors (PHDs) and hypoxia-inducible transcription factors (HIFs) are critical regulators of IPC and RIPC. In this review, we discuss recent findings concerning the role of the PHD-HIF axis in IPC and RIPC-mediated cardioprotection and examine molecular pathways and cell types that might be involved. We also appraise the therapeutic value of targeting the PHD-HIF axis to enhance cardiac tolerance against IRI.

  1. Spanish production of PhD Thesis in the field of guidance on TESEO database (2001-2012

    Directory of Open Access Journals (Sweden)

    Ferreira-Villa, Camino

    2013-04-01

    Full Text Available The objective of this research is to analyse the scientific production in PhD Thesis about guidance in Spain from 2001 to 2012. The data have been recollected on the TESEO database belonging to the Ministry of Education, Culture and Sport. It has realized a content analysis of the titles, keywords and abstracts and it has assessed of them their productivity, the general and methodological features and the subjects that have been studied. It has been obtained ninety PhD Thesis in relation to the field of guidance over the last ten years that have studied mainly curriculum and career development. El objetivo de este estudio es analizar la producción científica en Tesis Doctorales sobre orientación en España entre 2001 y 2012. Los datos han sido recogidos a través de la Base de datos TESEO del Ministerio de Educación, Cultura y Deporte. Se ha realizado un análisis de contenido de los títulos, descriptores y resúmenes, valorando la productividad del área, las principales características generales y metodológicas y las temáticas estudiadas. Se han obtenido noventa Tesis Doctorales relacionadas con el ámbito de la orientación en los últimos diez años que han estudiado principalmente aspectos sobre el currículum y el desarrollo vocacional.

  2. Ajateenistusest, ausalt! / Kim Järvepõld

    Index Scriptorium Estoniae

    Järvepõld, Kim

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke, 9. apr. 2007, lk. 7. Autor leiab, et põhiseaduslik nõue, mille järgi on kõik Eesti kodanikud kohustatud osa võtma riigikaitsest, pole vastavuses tegeliku olukorraga, ning arvab, et kohustuslik ajateenistus tuleb kaotada või viia kooskõlla põhiseadusega

  3. Ajateenistusest, ausalt! / Kim Järvepõld

    Index Scriptorium Estoniae

    Järvepõld, Kim

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke, 9. apr. 2007, lk. 7. Autor leiab, et põhiseaduslik nõue, mille järgi on kõik Eesti kodanikud kohustatud osa võtma riigikaitsest, pole vastavuses tegeliku olukorraga, ning arvab, et kohustuslik ajateenistus tuleb kaotada või viia kooskõlla põhiseadusega

  4. Retarderi na teškim vozilima

    Directory of Open Access Journals (Sweden)

    Joško Rapanić

    2012-10-01

    Full Text Available The objective of all the braking systems fitted in vehicles isto reduce the speed, as well as to keep them at a standstill. Inorder to increase the active road traffic safety, the experts inthe leading vehicle manufacturer companies are trying from day to day to find a more efficient solution of the highest possiblequality. Braking problems, i.e. problems of stopping the vehiclesare closely related to time, forces, momentum, mass andother physical quantities. This is best seen in the braking ofheavy duty vehicles, trucks, buses, where the braking efficacyis questionable due to high inertia forces caused by heavyweight and more recently relatively high speeds. Such vehiclesare fitted with system of brakes that operate on compressed airor combination of pneumatics and hydraulics, since the driverhas not got enough power to achieve appropriate braking effect.However, the biggest problems occur by trucks runningdownhill, when the braking system is operated continuously fora longer period of time. This causes heating and overheating ofthe system elements ("fading", thus reducing the braking effect.In extreme cases, particularly if the system is poorly maintained,it can eventually fail completely.Because of the mentioned reasons for difficulties in brakingof trucks, such vehicles have been recently fitted with anauxiliary slow-down system. This system is completely independentfromthe main one on the wheels and is used exclusivelyfor slowing down or for maintaining of speed.

  5. MICROBIOLOGICAL STUDY OF CSOM AT KIMS - AMALAPURAM

    Directory of Open Access Journals (Sweden)

    Nagaraja

    2016-01-01

    Full Text Available BACKGROUND In India, Chronic Suppurative Otitis Media (CSOM is a major public-health problem with a high-prevalence rate. Several organisms have been implicated in the causation of CSOM, posing a challenge to the management. This is further complicated by the problem of emerging antibiotic-resistant bacterial strains. OBJECTIVE We undertook the present study to identify the causative organisms in CSOM and their susceptibility patterns to antibiotics in a rural teaching hospital in South India. METHODS A total number of 100 ear swabs were bacteriologically investigated for the present study. All the swabs collected from patients with clinical diagnosis of CSOM visiting the ENT outpatient department of a rural teaching hospital from December 2014 to May 2015. All these are new patients who did not have recent treatment with antibiotics either locally or systemically. Another group of 30 ear swabs were collected from healthy individuals with no history of ear discharged for control study. RESULTS Of the 100 patients, 45 were males. Out of 100 swabs cultured, 95% were culture positive and 5% were culture negative. Of the culture positive cases, 70% were aerobes, 25% were anaerobes and 5% sterile. Further, of the 99% culture positive cases, gram positive isolates were 22(31.42% and gram negative isolates were 48(68.57%. The isolated organisms were Pseudomonas aeruginosa (n=26; 37.15%, Staphylococcus aureus (n=15; 21.43%, Klebsiella pneumonia (n=12; 17.15%, Proteus spp. (n=6; 8.57%, Escherichia coli (n=4; 5.72%, Coagulase Negative Staphylococcus (n=5; 7.14%, Streptococcus pyogenes (n=1; 1%, Streptococcus pneumoniae (n=1; 1%, Bacteroides (n=13; 52%, peptostreptococcus (n=11; 44% and Fusobacterium (n=1; 4%. When antibiotic susceptibility was assessed, organisms were most susceptible to amikacin, followed by g the Antibiotics tested for sensitivity of the Isolates Amikacin stands first followed by Gentamicin and Ciprofloxacin. CONCLUSION CSOM is a serious condition, which is the most common cause of hearing loss, especially in the developing world. In our study, Pseudomonas aeruginosa was the most common causative organism, and amikacin seemed to be the most effective antibiotic with low resistance rates.

  6. Erythropoietin inhibits HIF-1α expression via upregulation of PHD-2 transcription and translation in an in vitro model of hypoxia-ischemia.

    Science.gov (United States)

    Souvenir, Rhonda; Flores, Jerry J; Ostrowski, Robert P; Manaenko, Anatol; Duris, Kamil; Tang, Jiping

    2014-02-01

    Hypoxia inducible factor (HIF)-1α is the central transcriptional factor for the regulation of oxygen-associated genes in response to hypoxia. Erythropoietin (EPO), a hematopoietic growth factor, increases oxygen availability during hypoxia/ischemia and is associated with neuroprotection following hypoxia-ischemia in laboratory models of stroke. However, EPO has failed to translate in a clinical setting. Thus, it is critical to elucidate the key players in EPO-induced neuroprotection. Our preliminary studies have shown that EPO, as a downstream gene of HIF, inhibits HIF-1α in a dose-dependent manner in an in vitro model of hypoxia-ischemia. This study is designed to elucidate the primary mediator of EPO-induced HIF-1α inhibition and subsequent cell survival/neuroprotection. Oxygen and glucose deprivation (OGD) of nerve growth factor-differentiated rat pheochromocytoma (PC-12) cells were used to model hypoxia-ischemia in an in vitro environment. The profile of HIF-1α, HIF-2α and prolyl hydroxylase domain 2 (PHD-2) expression; HIF-1α and prolyl hydroxylase (PHD-2) mRNA levels; matrix metalloproteinase (MMP)-9; and cell death was evaluated in the presence and absence of either EPO or PHD-2 inhibitor during OGD. Our findings showed that EPO treatment resulted in an increase in PHD-2 transcription and translation, inhibition of HIF-1α expression, reactive oxygen species formation, and MMP-9 activity, resulting in increased cell survival after OGD. We also observed that EPO-induced cell survival/neuroprotection was reversed by siRNA silencing of PHD-2. This led to the conclusion that PHD-2 is a key mediator of EPO-induced HIF-1α inhibition and subsequent neuroprotection in an in vitro model of hypoxia-ischemia.

  7. The Role of Gender in the Employment, Career Perception and Research Performance of Recent PhD Graduates from Dutch Universities

    OpenAIRE

    Cathelijn J F Waaijer; Sonneveld, Hans; Buitendijk, Simone E.; van Bochove, Cornelis A.; van der Weijden, Inge C. M.

    2016-01-01

    Recent decades have seen a sharp increase in the number of female PhD graduates in the Netherlands. Currently, the share of females among newly graduated PhDs is almost on par with that of males. A considerable body of scientific studies has investigated the role of gender in the academic workplace. However, the role of gender in the careers of all PhD graduates, including those outside academia, has been studied less. In this study, we investigate gender differences in type of job, occupatio...

  8. Something going on in Milan: a review of the 4th International PhD Student Cancer Conference.

    Science.gov (United States)

    Segré, C

    2010-01-01

    The 4th International PhD Student Cancer Conference was held at the IFOM-IEO-Campus in Milan from 19-21 May 2010 http://www.semm.it/events_researchPast.phpThe Conference covered many topics related to cancer, from basic biology to clinical aspects of the disease. All attendees presented their research, by either giving a talk or presenting a poster. This conference is an opportunity to introduce PhD students to top cancer research institutes across Europe.THE CORE PARTICIPANTING INSTITUTES INCLUDED: European School of Molecular Medicine (SEMM)-IFOM-IEO Campus, MilanBeatson Institute for Cancer Research (BICR), GlasgowCambridge Research Institute (CRI), Cambridge, UKMRC Gray Institute of Radiation Biology (GIROB), OxfordLondon Research Institute (LRI), LondonPaterson Institute for Cancer Research (PICR), ManchesterThe Netherlands Cancer Institute (NKI), Amsterdam'You organizers have crushed all my prejudices towards Italians. Congratulations, I enjoyed the conference immensely!' Even if it might have sounded like rudeness for sure this was supposed to be a genuine compliment (at least, that's how we took it), also considering that it was told by a guy who himself was the fusion of two usually antithetical concepts: fashion style and English nationality.The year 2010 has marked an important event for Italian research in the international scientific panorama: the European School of Molecular Medicine (SEMM) had the honour to host the 4th International PhD Student Cancer Conference, which was held from 19-21 May 2010 at the IFOM-IEO-Campus (http://www.semm.it/events_researchPast.php) in Milan.The conference was attended by more than one hundred students, coming from a selection of cutting edge European institutes devoted to cancer research. The rationale behind it is the promotion of cooperation among young scientists across Europe to debate about science and to exchange ideas and experiences. But that is not all, it is also designed for PhD students to get in touch

  9. Effects of BmKIM on sodium current of isolated cardiomyocytes, transmembrane action potential and aconitine induced arrhythmia in vivo in rabbits%东亚钳蝎毒素多肽对家兔心室肌细胞钠电流和在体动作电位的影响以及抗心律失常作用研究

    Institute of Scientific and Technical Information of China (English)

    王腾; 黄从新; 江洪; 唐其柱; 杨波; 李庚山

    2009-01-01

    目的 探讨基因表达得到重组的东亚钳蝎毒素多肽(BmKXM)对家兔单个心室肌细胞钠电流(INa)和在体动作电位的影响,以及对抗乌头碱诱发的心律失常电活动的作用.方法 用酶解法分离家兔心室肌细胞,全细胞膜片钳技术记录所需INa.采用浮置式玻璃微电极记录在体心肌细胞跨膜动作电位,并监测体表心电图.结果 (1)BmKIM 能明显抑制心肌细胞INa,使INa的电流-电压(I-V)曲线显著上移,但I-V曲线的形态没有发生改变.BmKIM使失活曲线显著左移,50%的INa失活电压分别由用药前的(-70.8±2.6)mV变为(-84.84±3.5)mV(P<0.05).在BmKIM作用下,心肌细胞INa失活后恢复时间明显延长,用药前快、慢恢复时间常数(Tf和Ts)分别是(28.9±6.1)ms和(107±21.6)me,给予BmKIM后,τf和τs分别是(54.2±7.9)ms(P<0.05)和(211.1±34.6)ms(P<0.01).(2)BmKIM 能明显改变记录在体心肌细胞跨膜动作电位时程(APD)和幅度(APA)以及最大上升速率(Vmax),使APD50和APD90都明显缩短,APA和Vmax显著减小.心电图上表现为QT间期缩短,心率明显加快.(3)乌头碱能明显触发后除极,诱发室件心动过速(室速),动作电位上表现为早期后除极和(或)延迟后除极.相对心电图上表现为插入性室性早搏或尖端扭转型室速(发生率为77.8%).BmKIM能明显降低乌头碱诱发的心律失常发生率(22.2%,P<0.01),更不能触发室速.结论 BmKIM对兔的心室肌细胞,INa有明显的抑制作用,这种抑制作用是通过与失活态的钠通道结合而发挥生理学效应,BmKIM 可抑制形成动作电位的钠离子内流,对抗乌头碱所致的心律失常发生,为开发具有选择性直接针对钠通道的阻滞剂BmKIM的应用前景打下基础.%Objective To investigate the effects of recombinant BmKIM (poly-peptide derived from Asian Scorpion Buthus martensi Karsch) on the sodium current (INa) of isolated ventricular myocytes,transmembrane action potential and aconitine induced

  10. 丁宁对阵韩国削球选手金景娥的技战术效果研究%Study on Technical and Tactical Effect of DING Ning While Fighting with KIM Kyungah

    Institute of Scientific and Technical Information of China (English)

    郭德兵

    2012-01-01

    运用文献资料法、数理统计法、专家访谈法、录像观察法、乒乓球技战术三段指标评估等方法,对我国优秀乒乓球运动员丁宁对阵韩国削球选手金景娥的比赛录像视频进行了技战术效果的统计分析。结果显示:丁宁在发球抢和接发球抢攻段中技战术运用效果欠佳,主要表现在三、五板和二、四板球的衔接不够流畅;在相持段中整体的技战术运用的较为灵活、多样,并取得了良好的效果,但在处理对搓的过渡球及多回合的相持球上耐心和信心都有待提高。%By using the method of literature review, mathematical statistics, expert interview, video observation and the table tennis three sections of index evaluation, this paper studies the Chinese excellent table tennis player DING Ning's technical and tactical effect of chopping technique when against Kim Kyungah. The result shows that DING Ning' s spiral, placement and the treatment of neutral ball in serves snatches and receive -attack seg- ment are unconscionable. The changes of DING Ning' s loops ( spin speed ) in rally part gain control over the game and the effect is good. However, the psychological compressive capacity needs to be improved.

  11. Urinary tubular protein-based biomarkers in the rodent model of cisplatin nephrotoxicity: a comparative analysis of serum creatinine, renal histology, and urinary KIM-1, NGAL, and NAG in the initiation, maintenance, and recovery phases of acute kidney injury.

    Science.gov (United States)

    Sinha, Vikash; Vence, Luis M; Salahudeen, Abdulla K

    2013-03-01

    Several biomarkers are becoming available for the early detection of acute kidney injury (AKI), but few have been directly compared. To compare urinary kidney injury molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL), and N-acetyl glucosaminidase (NAG) against serum creatinine and renal histological score in the initiation, maintenance, and recovery phases of cisplatin (CP)-induced AKI. Sprague-Dawley rats (300-350 g) were injected once through their tail veins with CP (CP group) at 5.5 mg/kg or with same volume of normal saline vehicle (Control group). Rats were euthanized at 2, 4, 6, 12, and 24 hours, and on days 2, 3, 6, and 10 (n = 12 in the CP group and n = 6 in the Control group at each time point), and urine, blood, and kidney samples were analyzed. A significant increase in serum creatinine was noted by day 3 in the CP group versus Control group [1.46 (0.12) vs 0.28 (0.03) mg/dL; mean (SE); P CP group. Urinary kidney injury molecule-1 levels were significantly higher at 24 hours in the CP group than in the Control group [48.26 (13.13) vs 8.21 (3.31) pg/mg creatinine; P CP than in the Control group [NAG, 8.19 (0.82) vs 3.48 (0.40) pg/mg creatinine, P G 0.05; NGAL, 2911.80 (368.10) vs 1412.60 (250.20) pg/mg creatinine, P CP to discern the time course and pattern of expression.

  12. 博士论文选题研究%Research on Topic Selection of Ph.D. Thesis

    Institute of Scientific and Technical Information of China (English)

    夏庆霖; 赵鹏大

    2011-01-01

    Through statistically analyzing the topics of 102 Ph.D. thesis, the article advances the mare principles ror tnesis topic selection, such as frontier, application, innovation, challenge and feasibility. Finally, a new idea is proposed that thesis topic selection will be written into the guide of recruit students as an important reform item.%本文通过对102篇博士论文选题的统计分析,提出博士论文选题应遵循前沿性、应用性、创新性、挑战性和可行性五大原则,以及以选题为指南的博士生招生改革思路。

  13. Book review of "The Ethics of Coercion in Mass Casualty Medicine" by Griffin Trotter MD, PhD

    Directory of Open Access Journals (Sweden)

    Singh Sonal

    2007-10-01

    Full Text Available Abstract Public health ethics is neither taught widely in medical schools or schools of public health in the US or around the world. It is not surprising that health care professionals are particularly challenged when faced with ethical questions which extend beyond safeguarding the interests of their individual patients to matters that affect overall public good. The perceived threat of terror after September 11 2007, the anthrax attacks and the Katrina debacle are recent circumstances which may result in coercion. These have piqued the interest of medical professionals and the general public on public health ethics. The Ethics of Coercion in Mass Casualty Medicine written by Griffin Trotter MD, PhD attempts to fill a timely void in this area by examining the ethics of coercion in times of public health disasters.

  14. [Comment on "Meeting Ph.D. Graduates' needs in a changing global environment"] Challenges to fostering interdisciplinary graduate education

    Science.gov (United States)

    Kock, Beaudry

    C. Susan Weiler's article ("Meeting Ph.D. graduates' needs in a changing global environment," Eos, 55(13), 149, 151) calling for more care and attention to interdisciplinary graduate education illuminated an important and neglected issue. Weiler makes the excellent point that for society to manage complex natural systems effectively, it is imperative that we establish stronger connections between science and public policy. However, as a nation, the United States lacks the institutional research culture to foster this. Nor are we training sufficient numbers of professionals with the skills to make these connections; and when the small number of truly interdisciplinary scientists emerge annually into the workforce, there are few positions that fit them.I echo Weiler's call for increased interdisciplinary collaboration, and the necessary training to support this increase. However, there are some fundamental obstacles her article does not explore.

  15. A PHD in histone language: on the role of histone methylation in plant responses to phosphate deficiency.

    Science.gov (United States)

    Chandrika, Nulu Naga Prafulla; Sundaravelpandian, Kalaipandian; Schmidt, Wolfgang

    2013-06-01

    Post-translational modifications of core histones are important for various DNA-templated processes such as transcription and repair. We recently reported that the ALFIN LIKE 6 (AL6) gene, identified in a forward genetic screen, is critical for phosphate deficiency-induced root hair formation and several other processes associated with the regulation of cellular phosphate homeostasis. AL6 contains a Plant Homeo Domain (PHD) finger that can bind to trimethylated lysine 4 of histone H3 (H3K4me3). Homozygous mutants defective in AL6 expression form very short root hairs under phosphate-deficient conditions, presumably caused by altered expression of putative primary and secondary down-stream targets of AL6. In this Addendum, we speculate about possible roles of AL6, H3K4 trimethylation and other chromatin modifications in the adaptation of plants to low phosphate availability.

  16. The National Institute of Nursing Research Graduate Partnerships Program (NINR-GPP): an opportunity for PhD students.

    Science.gov (United States)

    Engler, Mary B; Austin, Joan K; Grady, Patricia

    2014-01-01

    The Institutional Graduate Partnerships Program (GPP) offered by the National Institute of Nursing Research (NINR) provides an exceptional opportunity for students who are enrolled in any PhD program in nursing across the nation to complete dissertation research on the premier research campus of the National Institutes of Health, Bethesda, MD. The goal of this doctoral fellowship program, which is up to 3 years in length, is to train promising doctoral students in basic and clinical research. This knowledge and skill set is necessary for the next generation of nurse scientists to ultimately conduct translational research. In this article, the authors describe the program, eligibility requirements, application procedures, and selection criteria for NINR-supported GPP nursing students. Also provided are tips for interested students and outcomes of current and former NINR-supported GPP students (NINR-GPP).

  17. Literature Review of Advantages and Disadvantages of Pre-planned Construction Projects 2013 PhD Conference

    DEFF Research Database (Denmark)

    Larsen, Jesper Kranker; Ussing, Lene Faber; Brunø, Thomas Ditlev

    2013-01-01

    a linear positive impact on the construction projects´ chances to meet budget and quality, and to reduce duration and risk in the project process. Gaps associated with pre-planning and construction projects were found by the review, and the problem should be further studied by a trend analysis to validate......The construction industry’s focus on pre-planning, with its advantages and disadvantages, has not been investigated in a literature review which gives a state of art understanding of the topic. The aim of the paper is to review related papers, to fulfill gaps in the literature which could...... be researched further in a Ph.D. project. The review model is conducted on papers, which all support an input, processing and output stage. 561 journal papers were found, and by the processing stages 95 A-papers were categorized in six correlated themes. The main finding of the review was that pre-planning has...

  18. Gender differential item functioning on a national field-specific test: The case of PhD entrance exam of TEFL in Iran

    Directory of Open Access Journals (Sweden)

    Alireza Ahmadi

    2016-01-01

    Full Text Available Differential Item Functioning (DIF exists when examinees of equal ability from different groups have different probabilities of successful performance in a certain item. This study examined gender differential item functioning across the PhD Entrance Exam of TEFL (PEET in Iran, using both logistic regression (LR and one-parameter item response theory (1-p IRT models. The PEET is a national test consisting of a centralized written examination designed to provide information on the eligibility of PhD applicants of TEFL to enter PhD programs. The 2013 administration of this test provided score data for a sample of 999 Iranian PhD applicants consisting of 397 males and 602 females. First, the data were subjected to DIF analysis through logistic regression (LR model. Then, to triangulate the findings, a 1-p IRT procedure was applied. The results indicated (1 more items flagged for DIF by LR than by 1-p IRT (2 DIF cancellation (the number of DIF items were equal for both males and females, as revealed through LR, (3 equal number of uniform and non-uniform DIF, as tracked via LR, and (4 female superiority in the test performance, as revealed via IRT analysis. Overall, the findings of the study indicated that PEET suffers from DIF. As such, test developers and policymakers (like NOET & MSRT are recommended to take these findings into serious consideration and exercise care in fair test practice by dedicating effort to more unbiased test development and decision making.

  19. Implementation of an Education-Focused PhD Program in Anatomy and Cell Biology at Indiana University: Lessons Learned and Future Challenges

    Science.gov (United States)

    Brokaw, James J.; O'Loughlin, Valerie D.

    2015-01-01

    In 2008, the Indiana University School of Medicine, in collaboration with the School of Education, admitted its first student to a newly approved PhD program in Anatomy and Cell Biology focusing on educational research rather than biomedical research. The goal of the program is twofold: (1) to provide students with extensive training in all of the…

  20. Eco-Driven Chemical Research in the Boundary Between Academia and Industry. PhD Students' Views on Science and Society

    Science.gov (United States)

    Sjöström, Jesper

    2013-10-01

    This paper examines and discusses the views on science and society held among PhD students working in two different industrially and environmentally driven research programmes in the broad area of green chemistry. It is based on thirteen in-depth interviews. The analysis shows three main ways of handling the situation as "post-academic" PhD student: (1) the student sees the PhD work mainly as a job and does not reflect about his/her research or the research funding, (2) the student is satisfied with the post-academic situation, accepts the established innovation policy discourse and is sceptical to traditional academic research, and (3) the student sees collaborative research programmes as a way to get funding, which can be used for secretly done basic research. Most PhD students either emphasise usefulness—in line with the dominating research policy discourse—or they adopt the positivistic view of science as objective and independent of the surrounding society. However, there are only a few signs of "double problematisation", that is a critical view where both disciplinary-oriented and industry-dependent research are problematised.