Results of surgical treatment versus chemoradiation therapy in oropharyngeal early tumors

Directory of Open Access Journals (Sweden)

Chedid, Helma Maria

2009-03-01

Full Text Available Introduction: The epidermoid carcinoma of the upper aerodigestive tract is diagnosed in approximately 40% of the cases of advanced clinical stages. Objective: To evaluate the disease-free interval in patients with clinical stages I and II epidermoid carcinoma who were submitted to surgery or chemoradiation. Method: Retrospective study of the records of 139 patients treated for oropharyngeal epidermoid carcinoma submitted to treatment with curative intent. Among those patients, 38 were classified with early tumors clinical stages I and II. Twenty-seven (71.1% underwent surgical treatment whereas eleven (28.9% were treated with chemoradiation. The mean age was 56.4 years; 31 cases (81.6% were in men and seven (18.4% were in women. Results: Among the eleven patients who were submitted to chemoradiation, 72.7% obtained locoregional control of the disease and their disease-free survival was of 42%. Among the 27 patients operated, 19 remained in Clinical Stages I and II in the histological report and six underwent postoperative radiation therapy. The disease-free interval for two years was of 70%. Conclusion: The patients submitted to the surgery had a better disease-free interval as compared to those submitted to chemoradiation treatment.

Replication Kits for the papers "Automated Usability Evaluation of Virtual Reality Applications" and "VR Interaction Modalities for the Evaluation of Technical Device Prototypes" submitted to the CHI 2018

OpenAIRE

Harms, Patrick; Holderied, Hanna

2017-01-01

This replication kit contains all necessary data to reproduce the setup and results of both papers 'Automated Usability Evaluation of Virtual Reality Applications' and 'VR Interaction Modalities for the Evaluation of Technical Device Prototypes' as submitted to the CHI 2018. It includes the Unity Projects that show a coffee machine and a copier scene (sometimes refered to as printer scene, as well, as it is an integrated device) that can be interacted with with the help of the four interactio...

Improving early cycle economic evaluation of diagnostic technologies

NARCIS (Netherlands)

Steuten, Lotte Maria Gertruda; Ramsey, Scott D.

2014-01-01

The rapidly increasing range and expense of new diagnostics, compels consideration of a different, more proactive approach to health economic evaluation of diagnostic technologies. Early cycle economic evaluation is a decision analytic approach to evaluate technologies in development so as to

Metabolic evaluation of dairy cows submitted to three different strategies to decrease the effects of negative energy balance in early postpartum

Directory of Open Access Journals (Sweden)

Alejandra M.B García

2011-12-01

Full Text Available In early lactation dairy cattle suffer metabolic alterations caused by negative energy balance, which predisposes to fatty liver and ketosis. The aim of this study was to evaluate the metabolic condition of high yielding dairy cows subjected to three treatments for preventing severe lipomobilization and ketosis in early lactation. Fifty four multiparous Holstein cows yielding >30 L/day were divided into four groups: control (CN= no treatment, glucose precursor (PG= propylene-glycol, hepatic protector (Mp= Mercepton®, and energy supplement with salts of linolenic and linoleic faty acids (Mg-E= Megalac-E®. Treatments were administrated randomly at moment of calving until 8 weeks postpartum. Blood samples were collected on days 1, 7, 14, 21, 28, 35, 42 and 49 postpartum. Body condition score (BCS was evaluated at the same periods and milk yield was recorded at 2nd, 4th, 5th, 6th, 7th, and 8th weeks of lactation. Concentrations of non-esterified fatty acids (NEFA, albumin, AST, ß-hydroxybutyrate (BHBA, cholesterol, glucose, total protein, urea and triglycerides were analyzed in blood samples. Cut-off points for subclinical ketosis were defined when BHBA >1.4 mmol/L and NEFA >0.7 mmol/L. General occurrence of subclinical ketosis was 24% during the period. An ascendant curve of cholesterol and glucose was observed from the 1st to the 8th week of lactation, while any tendency was observed with BHBA and NEFA, although differences among treatments were detected (p<0.05. BCS decreased from a mean of 3.85 at 1st week to 2.53 at 8th week of lactation (p=0.001. Milk yield was higher in the Mg-E group compared with the other treatment groups (p<0.05 Compared with the CN group, the treatments with Mp and PG did not show significant differences in blood biochemistry and milk yield. Cows receiving PG and Mg-E showed higher values of BHBA and NEFA (P<0.05, indicating accentuated lipomobilization. Supplementation with Mg-E also resulted in significant higher

Early economic evaluation of emerging health technologies: protocol of a systematic review

Science.gov (United States)

2014-01-01

Background The concept of early health technology assessment, discussed well over a decade, has now been collaboratively implemented by industry, government, and academia to select and expedite the development of emerging technologies that may address the needs of patients and health systems. Early economic evaluation is essential to assess the value of emerging technologies, but empirical data to inform the current practice of early evaluation is limited. We propose a systematic review of early economic evaluation studies in order to better understand the current practice. Methods/design This protocol describes a systematic review of economic evaluation studies of regulated health technologies in which the evaluation is conducted prior to regulatory approval and when the technology effectiveness is not well established. Included studies must report an economic evaluation, defined as the comparative analysis of alternatives with respect to their associated costs and health consequences, and must evaluate some regulated health technology such as pharmaceuticals, biologics, high-risk medical devices, or biomarkers. We will conduct the literature search on multiple databases, including MEDLINE, EMBASE, the Centre for Reviews and Dissemination Databases, and EconLit. Additional citations will be identified via scanning reference lists and author searching. We suspect that many early economic evaluation studies are unpublished, especially those conducted for internal use only. Additionally, we use a chain-referral sampling approach to identify authors of unpublished studies who work in technology discovery and development, starting out with our contact lists and authors who published relevant studies. Citation screening and full-text review will be conducted by pairs of reviewers. Abstracted data will include those related to the decision context and decision problem of the early evaluation, evaluation methods (e.g., data sources, methods, and assumptions used to

Thromboelastometric evaluation of horses submitted to experimental thrombosis and jugular thrombectomy

Directory of Open Access Journals (Sweden)

Dietrich Pizzigatti

Full Text Available Abstract: Jugular thrombosis in horses occurs commonly in iatrogenic situations, secondary to endotoxemic clinical condition and disseminated vascular coagulation, potentially leading to death. Thus, hemostatic evaluation becomes necessary and extremely important for monitoring the risks of systemic hypercoagulability and for the efficiency of allopathic and surgical treatment. This paper describes the hemostatic behavior in experimental jugular thrombosis of ten healthy equines, subsequently submitted to two thrombectomy techniques and receiving heparin sodium as anti-rethrombosis therapy. These animals were evaluated for 20 days by thromboelastometry (TEM, platelet count, hematocrit and fibrinogen, at four moments: pre-induction to phlebitis (D0-MPF; three days after thrombophlebitis induction (D3-MFM; 6 days after, - moment of thrombophlebitis - (D9-MT; and 54 (D16 and 126 (D19 hours after thrombectomies (PTM. Thrombectomy was performed via a Vollmar Ring (group 1, n=5 and Fogarty catheter (group 2, n=5. All the animals received heparin (150 UI/kg, SC every 12 hours, for ten days after the respective thrombectomies. Through the blood samples were evaluated TEM, activated partial thromboplastin time (aPTT and prothrombin time (PT, dosing of fibrinogen, hematocrit and platelet count at the abovementioned moments. For comparison between groups and moments the t test was applied at 5% significance level. No significant difference was verified between treatment groups at any of the moments. There were reductions in clotting time (CT and clot formation time (CFT, with increase in maximum lysis (ML until the moment D9-MT. Evaluation through INTEM® reagent presented prolongations of CT and CFT with reduction of α angle and ML starting from D16 and D19. Similarly, aPTT presented significant differences between moments pre- (D0, 3 and 9 and post- (D16 and 19 anticoagulant and surgical treatment. The platelet numbers were diminished at moments D16 and

Early Detection of Brain Pathology Suggestive of Early AD Using Objective Evaluation of FDG-PET Scans

Directory of Open Access Journals (Sweden)

James C. Patterson

2011-01-01

Full Text Available The need for early detection of AD becomes critical as disease-modifying agents near the marketplace. Here, we present results from a study focused on improvement in detection of metabolic deficits related to neurodegenerative changes consistent with possible early AD with statistical evaluation of FDG-PET brain images. We followed 31 subjects at high risk or diagnosed with MCI/AD for 3 years. 15 met criteria for diagnosis of MCI, and five met criteria for AD. FDG-PET scans were completed at initiation and termination of the study. PET scans were read clinically and also evaluated objectively using Statistical Parametric Mapping (SPM. Using standard clinical evaluation of the FDG-PET scans, 11 subjects were detected, while 18 were detected using SPM evaluation. These preliminary results indicate that objective analyses may improve detection; however, early detection in at-risk normal subjects remains tentative. Several FDA-approved software packages are available that use objective analyses, thus the capacity exists for wider use of this method for MCI/AD.

Evaluation of rheological behavior and sensory properties of ready to eat salad dressings submitted to irradiation

International Nuclear Information System (INIS)

Gallo, Juliana Maria Altavista Sagretti

2013-01-01

This study evaluated the rheological behavior of 11 salad dressings ready to eat, processed by gamma irradiation, at doses: 3 kGy and 5 kGy. This assessment was made by rheograms traced by measurements of viscosity and shear stress by shear rate. Mathematical parameters obtained from these measures also contributed to the conclusion of the behavior exhibited and for choosing the best mathematical model applicable to them. The measurements were performed on a Brookfield viscometer Model LVDV - III. The Neslab thermal bath was used to maintain ambient temperature during the whole analysis. This study protocol was done in two stages. In step 1, the evaluation was performed soon after the samples have been irradiated when these were close to their dates of manufacture. In phase 2 the samples were reassessed after a period of storage, near the expiration date of their validity. Simultaneously pH measurement was performed to evaluate their stability in the face of treatment and sensory analyzes of two salad dressings were studied, in order to verify the acceptance of these when submitted to irradiation. The shear-thinning behavior was confirmed for all dressings through the mathematical model, the power law, that best model apply to this, in both phases. The irradiation at the absorbed doses studied did not influence this behavior. The results of sensory evaluation indicated good acceptance of irradiated sauces for the tasters. (author)

Rectal dose assessment in patients submitted to high-dose-rate brachytherapy for uterine cervix cancer

International Nuclear Information System (INIS)

Oliveira, Jetro Pereira de; Batista, Delano Valdivino Santos; Bardella, Lucia Helena; Carvalho, Arnaldo Rangel

2009-01-01

Objective: The present study was aimed at developing a thermoluminescent dosimetric system capable of assessing the doses delivered to the rectum of patients submitted to high-dose-rate brachytherapy for uterine cervix cancer. Materials and methods: LiF:Mg,Ti,Na powder was the thermoluminescent material utilized for evaluating the rectal dose. The powder was divided into small portions (34 mg) which were accommodated in a capillary tube. This tube was placed into a rectal probe that was introduced into the patient's rectum. Results: The doses delivered to the rectum of six patients submitted to high-dose-rate brachytherapy for uterine cervix cancer evaluated by means of thermoluminescent dosimeters presented a good agreement with the planned values based on two orthogonal (anteroposterior and lateral) radiographic images of the patients. Conclusion: The thermoluminescent dosimetric system developed in the present study is simple and easy to be utilized as compared to other rectal dosimetry methods. The system has shown to be effective in the evaluation of rectal doses in patients submitted to high-dose-rate brachytherapy for uterine cervix cancer. (author)

Evaluation of Early-Age Concrete Compressive Strength with Ultrasonic Sensors.

Science.gov (United States)

Yoon, Hyejin; Kim, Young Jin; Kim, Hee Seok; Kang, Jun Won; Koh, Hyun-Moo

2017-08-07

Surface wave velocity measurement of concrete using ultrasonic sensors requires testing on only one side of a member. Thus, it is applicable to concrete cast inside a form and is often used to detect flaws and evaluate the compressive strength of hardened concrete. Predicting the in situ concrete strength at a very early stage inside the form helps with determining the appropriate form removal time and reducing construction time and costs. In this paper, the feasibility of using surface wave velocities to predict the strength of in situ concrete inside the form at a very early stage was evaluated. Ultrasonic sensors were used to measure a series of surface waves for concrete inside a form in the first 24 h after placement. A continuous wavelet transform was used to compute the travel time of the propagating surface waves. The cylindrical compressive strength and penetration resistance tests were also performed during the test period. Four mixtures and five curing temperatures were used for the specimens. The surface wave velocity was confirmed to be applicable to estimating the concrete strength at a very early age in wall-like elements. An empirical formula is proposed for evaluating the early-age compressive strength of concrete considering the 95% prediction intervals.

Renal structure and function evaluation of rats from dams that received increased sodium intake during pregnancy and lactation submitted or not to 5/6 nephrectomy.

Science.gov (United States)

Marin, Evelyn Cristina Santana; Balbi, Ana Paula Coelho; Francescato, Heloísa Della Coletta; Alves da Silva, Cleonice Giovanini; Costa, Roberto Silva; Coimbra, Terezila M

2008-01-01

Adult rats submitted to perinatal salt overload presented renin-angiotensin system (RAS) functional disturbances. The RAS contributes to the renal development and renal damage in a 5/6 nephrectomy model. The aim of the present study was to analyze the renal structure and function of offspring from dams that received a high-salt intake during pregnancy and lactation. We also evaluated the influence of the prenatal high-salt intake on the evolution of 5/6 nephrectomy in adult rats. A total of 111 sixty-day-old rat pups from dams that received saline or water during pregnancy and lactation were submitted to 5/6 nephrectomy (nephrectomized) or to a sham operation (sham). The animals were killed 120 days after surgery, and the kidneys were removed for immunohistochemical and histological analysis. Systolic blood pressure (SBP), albuminuria, and glomerular filtration rate (GFR) were evaluated. Increased SBP, albuminuria, and decreased GFR were observed in the rats from dams submitted to high-sodium intake before surgery. However, there was no difference in these parameters between the groups after the 5/6 nephrectomy. The scores for tubulointerstitial lesions and glomerulosclerosis were higher in the rats from the sham saline group compared to the same age control rats, but there was no difference in the histological findings between the groups of nephrectomized rats. In conclusion, our data showed that the high-salt intake during pregnancy and lactation in rats leads to structural changes in the kidney of adult offspring. However, the progression of the renal lesions after 5/6 nephrectomy was similar in both groups.

Early genetic evaluation of open-pollinated Douglas-fir families

Science.gov (United States)

Kurt H. Riitters; David A. Perry

1987-01-01

In a test of early genetic evaluation of the growth potential of 14 families of open-pollinated Douglas-fir (Pseudotsuga menziesii) [Mirb.] Franco), measures of growth and phenology of seedligns grown in a coldframe were correlated with height of saplings in evaluation plantations at 9, 12, and 15 years. fifteen-year height was most strongly...

[Materno-fetal acid-base equilibrium evaluation in parturients submitted to ketamine anesthesia (author's transl)].

Science.gov (United States)

Mauad Filho, F; Meirelles, R S

1975-01-01

In the present work ketamine was used as anesthetic during the labor in order to evaluate the effect of this anesthetic on the binominal fetus-mother. Two groups of parturients and their fetuses, were studied: 1) The experimental group, with 22 parturients and their fetuses submitted to ketamine anesthesia during the labord, and 2) The control group, with 20 parturients and their fetuses without any analgesic treatment during the labor. In 20 cases of the experimental group the anesthetic was injected during the delivery labor and the other two just before it. It were evaluated in the mother's blood the biochemical parameters of the acid-base balance and others collateral effects of the anesthesia; on the fetus's side the same parameters also and the cardiac frequency. The newborn were evaluated by Apgar Score during the first and fifth minutes of life. The incidence of the spontaneous delivery in the experimental group, was 78%; in 22% of these patients the forceps of relief was used. In 22 cases in which Ketamine was applied it were observed, the following events: elevation of the blood pressure (50%), perineum rigidness (18%), dreams and or hallucinations (18%), increase of the cardiac frequency (9%), apneia (4%) and nausea (4%). It was also observed an increase of uterine tonus an abolishment of abdominal press during the delivery labor, studied through the uterine electromyography register. It was noted after the Ketamine application a fall in the pH of the maternal peripherical venous blood, fetal skull blood and the pH of the blood of the umbilical vein. 22% of the newborns, from the experimental group, presented a depression in the first minute of life (Apgar less than or equals to 6). The pCO2 values in the blood of the umbilical artery were higher in the experimental group than in the control one.

Dosimetry of patients submitted to cerebral PET/CT for the diagnosis of mild cognitive impairment

Energy Technology Data Exchange (ETDEWEB)

Santana, Priscila do Carmo; Oliveira, Paulo Marcio Campos de; Bernardes, Felipe Dias; Mamede, Marcelo, E-mail: pridili@gmail.com [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil); Mourao, Arnaldo Prata [Centro Federal de Educacao Tecnologica de Minas Gerais (CEFET), Belo Horizonte, MG (Brazil); Silva, Teogenes Augusto da [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

2014-11-15

Objective: the present study was aimed at evaluating the effective radiation dose in patients submitted to PET/CT for the diagnosis of mild cognitive impairment. Materials and methods: TLD-100 detectors inserted into an Alderson Rando® anthropomorphic phantom were utilized to measure the absorbed dose coming from the CT imaging modality. The anthropomorphic phantoms (male and female adult versions) were submitted to the same technical protocols for patients’ images acquisition. The absorbed dose resulting from the radiopharmaceutical injection was estimated by means of the model proposed by the ICRP publication 106. Results: the effective dose in patients submitted to this diagnostic technique was approximately (5.34 ± 1.99) mSv. Conclusion: optimized protocols for calculation of radioactive activity injected into patients submitted to this diagnostic technique might contribute to reduce the effective radiation dose resulting from PET/CT in the diagnosis of mild cognitive impairment. (author)

Dosimetry of patients submitted to cerebral PET/CT for the diagnosis of mild cognitive impairment

International Nuclear Information System (INIS)

Santana, Priscila do Carmo; Oliveira, Paulo Marcio Campos de; Bernardes, Felipe Dias; Mamede, Marcelo; Mourao, Arnaldo Prata; Silva, Teogenes Augusto da

2014-01-01

Objective: the present study was aimed at evaluating the effective radiation dose in patients submitted to PET/CT for the diagnosis of mild cognitive impairment. Materials and methods: TLD-100 detectors inserted into an Alderson Rando® anthropomorphic phantom were utilized to measure the absorbed dose coming from the CT imaging modality. The anthropomorphic phantoms (male and female adult versions) were submitted to the same technical protocols for patients’ images acquisition. The absorbed dose resulting from the radiopharmaceutical injection was estimated by means of the model proposed by the ICRP publication 106. Results: the effective dose in patients submitted to this diagnostic technique was approximately (5.34 ± 1.99) mSv. Conclusion: optimized protocols for calculation of radioactive activity injected into patients submitted to this diagnostic technique might contribute to reduce the effective radiation dose resulting from PET/CT in the diagnosis of mild cognitive impairment. (author)

Study of the early age cracking of concrete massive structures: effect of the temperature decrease rate, steel reinforcement and construction joints

International Nuclear Information System (INIS)

Briffaut, M.

2010-01-01

At early-age, massive concrete structures (ex. nuclear power plant) are submitted to strains due to the hydration reaction. If they are restrained, crossing cracks can occurs. This cracking may increase significantly the concrete wall permeability. The objectives of this work was to characterize the early age concrete behavior (thermal and endogenous shrinkage, basic and thermal transient creep, mechanical characteristic evolution) as well as develop a new device to study the early age cracking of a concrete structure submitted to restrained shrinkage. The experimental campaign achieved with this new device (called thermal active ring test) and the numerical analysis of the test thanks to finite element simulations allows us to evaluate the coupling between creep and damage, to identify the tensile strength decrease due to construction joints and to quantify the effect of reinforcement on the concrete behaviour. Moreover, with this device, permeability measurements have been performed on a cracked specimen. Finally, numerical simulations of massive structures highlight the influence of boundary conditions for restrained shrinkage and the influence of the coupling between creep and damage on the damage pattern. (author)

Early evaluation and value-based pricing of regenerative medicine technologies.

Science.gov (United States)

Koerber, Florian; Rolauffs, Bernd; Rogowski, Wolf

2013-11-01

Since the first pioneering scientists explored the potential of using human cells for therapeutic purposes the branch of regenerative medicine has evolved to become a mature industry. The focus has switched from 'what can be done' to 'what can be commercialized'. Timely health economic evaluation supports successful marketing by establishing the value of a product from a healthcare system perspective. This article reports results from a research project on early health economic evaluation in collaboration with developers, clinicians and manufacturers. We present an approach to determine an early value-based price for a new treatment of cartilage defects of the knee from the area of regenerative medicine. Examples of using evaluation results for the purpose of business planning, market entry, preparing the coverage decision and managed entry are discussed.

Shared-Reading Volume in Early Childhood Special Education Classrooms

Science.gov (United States)

Dynia, Jaclyn M.; Justice, Laura M.

2015-01-01

This study describes book reading practices occurring in early childhood special education (ECSE) classrooms in comparison to early childhood education (ECE) classrooms. Reading logs submitted by 19 ECSE teachers and 13 ECE teachers over one academic year included all books read in whole class settings; these logs were analyzed to assess the…

Evaluation of early changes of cartilage biomarkers following ...

African Journals Online (AJOL)

Evaluation of early changes of cartilage biomarkers following arthroscopic meniscectomy in young Egyptian adults. ... Asked Questions about PDFs. Alternatively, you can download the PDF file directly to your computer, from where it can be opened using a PDF reader. To download the PDF, click the Download link above.

How to Submit a Risk Management Plan (RMP) to EPA

Science.gov (United States)

RMP*eSubmit software is the only way to submit RMPs. After you have prepared your plan using RMP*eSubmit, you may also re-submit, correct, or withdraw an RMP. Another electronic tool, RMP*Comp, performs the required off-site consequence analysis.

Endometrium evaluation with high-field (3-Tesla) magnetic resonance imaging in patients submitted to uterine leiomyoma embolization

International Nuclear Information System (INIS)

Jacobs, Monica Amadio Piazza; Nasser, Felipe; Zlotnik, Eduardo; Messina, Marcos de Lorenzo; Baroni, Ronaldo Hueb

2013-01-01

To evaluate the endometrial alterations related to embolization of uterine arteries for the treatment of symptomatic uterine leiomyomatosis (pelvic pain and/or uterine bleeding) by means of high-field (3-Tesla) magnetic resonance. This is a longitudinal and prospective study that included 94 patients with a clinical and imaging diagnosis of symptomatic uterine leiomyomatosis, all of them treated by embolization of the uterine arteries. The patients were submitted to evaluations by high-field magnetic resonance of the pelvis before and 6 months after the procedure. Specific evaluations were made of the endometrium on the T2-weighted sequences, and on the T1-weighted sequences before and after the intravenous dynamic infusion of the paramagnetic contrast. In face of these measures, statistical analyses were performed using Student's t test for comparison of the results obtained before and after the procedure. An average increase of 20.9% was noted in the endometrial signal on T2-weighted images obtained after the uterine artery embolization procedure when compared to the pre-procedure evaluation (p=0.0004). In the images obtained with the intravenous infusion of paramagnetic contrast, an average increase of 18.7% was noted in the post-embolization intensity of the endometrial signal, compared to the pre-embolization measure (p<0.035). After embolization of the uterine arteries, there was a significant increase of the endometrial signal on the T2-weighted images and on the post-contrast images, inferring possible edema and increased endometrial flow. Future studies are needed to assess the clinical impact of these findings

Endometrium evaluation with high-field (3-Tesla) magnetic resonance imaging in patients submitted to uterine leiomyoma embolization

Energy Technology Data Exchange (ETDEWEB)

Jacobs, Monica Amadio Piazza [Post-graduation Program in Abdominal Imaging, Hospital Israelita Albert Einstein, São Paulo, SP (Brazil); Nasser, Felipe [Intervention Radiology Department, Hospital Israelita Albert Einstein, São Paulo, SP (Brazil); Zlotnik, Eduardo; Messina, Marcos de Lorenzo [Gynecology and Obstetrics Department, Hospital Israelita Albert Einstein, São Paulo, SP (Brazil); Baroni, Ronaldo Hueb [Magnetic Resonance Unit, Imaging Department, Hospital Israelita Albert Einstein, São Paulo, SP (Brazil)

2013-07-01

To evaluate the endometrial alterations related to embolization of uterine arteries for the treatment of symptomatic uterine leiomyomatosis (pelvic pain and/or uterine bleeding) by means of high-field (3-Tesla) magnetic resonance. This is a longitudinal and prospective study that included 94 patients with a clinical and imaging diagnosis of symptomatic uterine leiomyomatosis, all of them treated by embolization of the uterine arteries. The patients were submitted to evaluations by high-field magnetic resonance of the pelvis before and 6 months after the procedure. Specific evaluations were made of the endometrium on the T2-weighted sequences, and on the T1-weighted sequences before and after the intravenous dynamic infusion of the paramagnetic contrast. In face of these measures, statistical analyses were performed using Student's t test for comparison of the results obtained before and after the procedure. An average increase of 20.9% was noted in the endometrial signal on T2-weighted images obtained after the uterine artery embolization procedure when compared to the pre-procedure evaluation (p=0.0004). In the images obtained with the intravenous infusion of paramagnetic contrast, an average increase of 18.7% was noted in the post-embolization intensity of the endometrial signal, compared to the pre-embolization measure (p<0.035). After embolization of the uterine arteries, there was a significant increase of the endometrial signal on the T2-weighted images and on the post-contrast images, inferring possible edema and increased endometrial flow. Future studies are needed to assess the clinical impact of these findings.

FLT-PET for early response evaluation of colorectal cancer patients with liver metastases

DEFF Research Database (Denmark)

Mogensen, Marie Benzon; Loft, Annika; Aznar, Marianne

2017-01-01

BACKGROUND: Fluoro-L-thymidine (FLT) is a positron emission tomography/computed tomography (PET/CT) tracer which reflects proliferative activity in a cancer lesion. The main objective of this prospective explorative study was to evaluate whether FLT-PET can be used for the early evaluation...... standardised uptake values (SUVmax, SUVmean) were measured. After three cycles of chemotherapy, treatment response was assessed by CT scan based on RECIST 1.1. RESULTS: Thirty-nine consecutive patients were included of which 27 were evaluable. Dropout was mainly due to disease complications. Nineteen patients...... between the response according to RECIST and the early changes in FLT uptake measured as SUVmax(p = 0.24). CONCLUSIONS: No correlation was found between early changes in FLT uptake after the first cycle of treatment and the response evaluated from subsequent CT scans. It seems unlikely that FLT-PET can...

Evaluation of possible associated factors for early childhood caries and severe early childhood caries: a multicenter cross-sectional survey

NARCIS (Netherlands)

Özen, B.; van Strijp, A.J.P.; Özer, L.; Olmus, H.; Genc, A.; Cehreli, S.B.

2016-01-01

Objectives: The present study evaluated associated factors for developing early childhood caries (ECC) and Severe-ECC (S-ECC) in a group of children aged 24–71 months. Potential positive effects of early dental visit on formation of ECC is investigated as well. Study Design: This was a multicenter,

76 FR 12978 - Advisory Committee on the Maternal, Infant and Early Childhood Home Visiting Program Evaluation...

Science.gov (United States)

2011-03-09

... and Early Childhood Home Visiting Program Evaluation will meet for its first session on Wednesday... Administration for Children and Families Advisory Committee on the Maternal, Infant and Early Childhood Home...: Advisory Committee on the Maternal, Infant and Early Childhood Home Visiting Program Evaluation. Date and...

Performance evaluation of early maize genotypes in far western hills of Nepal

OpenAIRE

Hari Kumar Prasai; Ujjawal Kumar Singh Kushwaha; Bishnu Prasad Joshi; Jiban Shrestha

2015-01-01

Initial evaluation trial of maize (early) genotypes was carried out at Regional Agricultural Research Station, Doti, Nepal in 2013 and 2014. Total fourteen and fifteen genotypes of early maize were included in initial evaluation experiment of the year 2013 and 2014 respectively. The experiment was laid out in randomized complete block design (RCBD) with three replications in each year. Out of the tested genotypes, SO3TEY/LN, ZM 423 and SO3TEY-FM (ER) identified as promising from statistical a...

Marital conflict and early adolescents' self-evaluation: the role of parenting quality and early adolescents' appraisals.

Science.gov (United States)

Siffert, Andrea; Schwarz, Beate; Stutz, Melanie

2012-06-01

Cognitive appraisals and family dynamics have been identified as mediators of the relationship between marital conflict and children's adjustment. Surprisingly little research has investigated both meditational processes in the same study. Guided by the cognitive-contextual framework and the spillover hypothesis, the present study integrated factors from both theories early adolescents' appraisals of threat and self-blame, as well as perceived parenting quality as mediators of the link between early adolescents' perception of marital conflict and their self-evaluations (self-esteem and scholastic competence). Analyses were based on the first two waves of an ongoing longitudinal study. Participants were 176 two-parent families, and their early adolescents (50.5% girls) whose mean age was 10.61 years at Time 1 (SD =0.40) and 11.63 years at Time 2 (SD=0.39). Structural equation modeling analyses indicated that parenting quality and early adolescents' perceived threat provided indirect pathways between marital conflict and early adolescents' self-esteem 1 year later when controlling for their initial level of self-esteem. With respect to scholastic competence, only fathers' parenting was an indirect link. Self-blame did not play a role. Implications for understanding the mechanisms by which exposure to marital conflict predicts early adolescents' maladjustment are discussed.

The case for applying an early-lifecycle technology evaluation methodology to comparative evaluation of requirements engineering research

Science.gov (United States)

Feather, Martin S.

2003-01-01

The premise of this paper is taht there is a useful analogy between evaluation of proposed problem solutions and evaluation of requirements engineering research itself. Both of these application areas face the challenges of evaluation early in the lifecycle, of the need to consider a wide variety of factors, and of the need to combine inputs from multiple stakeholders in making thse evaluation and subsequent decisions.

Content Analysis of Papers Submitted to Communications in Information Literacy, 2007-2013

Directory of Open Access Journals (Sweden)

Christopher V. Hollister

2014-07-01

Full Text Available The author conducted a content analysis of papers submitted to the journal, Communications in Information Literacy, from the years 2007-2013. The purpose was to investigate and report on the overall quality characteristics of a statistically significant sample of papers submitted to a single-topic, open access, library and information science (LIS journal. Characteristics of manuscript submissions, authorship, reviewer evaluations, and editorial decisions were illuminated to provide context; particular emphasis was given to the analysis of major criticisms found in reviewer evaluations of rejected papers. Overall results were compared to previously published research. The findings suggest a trend in favor of collaborative authorship, and a possible trend toward a more practice-based literature. The findings also suggest a possible deterioration in some of the skills that are required of LIS authors relative to the preparation of scholarly papers. The author discusses potential implications for authors and the disciplinary literature, recommends directions for future research, and where possible, provides recommendations for the benefit of the greater community of LIS scholars.

Changes in cardiac adrenergic nervous system in patients submitted to transmyocardial laser revascularisation - assessment with I-123-MIBG SPECT

International Nuclear Information System (INIS)

Teresinska, A.; Sliwinski, M.; Konieczna, S.; Szymanska, M.; Hendzel, P.; Juraszynski, Z.; Wojnowski, A.; Debski, A.; Szumilak, B.

2002-01-01

Meta-iodobenzylguanidine [MIBG] is an analogue of guanethidine, which, after labelling with iodine-123, has been used for cardiac neuronal imaging in conditions such as coronary artery disease, myocardial infarction, heart failure, cardiac arrhythmia, diabetes mellitus, heart transplantation. The aim of our program using I-123-Mibg is: 1) to study the range of influence of the laser energy (CO 2 -high power laser) during trans myocardial laser revascularisation [Tml] on cardiac adrenergic nervous system, and 2) to assess if disruption of this system can be one of the mechanisms responsible for clinical improvement observed early after Tml. Methods: The patients with high pre-operative probability of having sole TMLR or TMLR combined with only 1 bypass are studied before the operation for neuronal activity with I-123-MIBG SPECT [MIBG-0]. The patients (if they were operated according to the assumption) are studied postoperatively with I-123-MIBG SPECT as early as possible from clinical point of view [MIBG-early] and 6 months after operation [MIBG-6m]. Up to now, in 27 pts the preoperative and early postoperative (7-39 days, av. 13±7 days) tests were performed and in 15 pts - also MIBG-6m was performed. The group characteristics: 21M (78%); age: 43-76y, av. 64±10y; all the patients in III/IV CCS class; 20 pts (74%) after 1-2 MI; 5 pts (19%) after earlier CABG or PTCA. Registration of I-123-MIBG SPECT images was started 4 hrs after injection of the radiopharmaceutical. All SPECT studies were assessed in 17 segments (seg) of the LV. The bypassed seg and the septal seg were excluded from the assessment (as not submitted to the laser). Results: In 22 studies (32%), the evaluation of MIBG uptake was not possible because of very low heart uptake and/or very high extra cardiac uptake. Finally, 18 of the preoperative, 18 of the early postoperative and 11 of the late postoperative studies were submitted to segmental analysis. In MIBG-0, there were 172 uptake defects in

Brief Report: An Evaluation of an Australian Autism-Specific, Early Intervention Programme

Science.gov (United States)

Paynter, Jessica M.; Riley, Emma P.; Beamish, Wendi; Scott, James G.; Heussler, Helen S.

2015-01-01

There is a relative paucity of evidence examining the effectiveness of early intervention for young children with Autism Spectrum Disorder, in particular those delivered through educationally-based programmes. This study aimed to evaluate the real world effectiveness of a community-based autism-specific early learning and intervention programme in…

78 FR 23936 - Early Retiree Reinsurance Program

Science.gov (United States)

2013-04-23

... operational processes, including those that involve plan sponsors' reporting and submitting of information, in... make available to the plan sponsor an Early Retiree List Response File (up to 7 business days), and a... Reinsurance Program (ERRP) in preparation for the January 1, 2014 program sunset date. These operational...

Evaluation of patients submitted to the arthroscopic treatment of the lateral epicondylitis refractory to the conservative treatment

Directory of Open Access Journals (Sweden)

Fabio Alexandre Martynetz

2013-12-01

Full Text Available Objective: to evaluate the results of the arthroscopic treatment of the lateral epicondylitis. Methods: we evaluated 14 patients (15 elbows submitted to the arthroscopic treatment of the lateral epicondylitis refractory to the conservative treatment, which was realized for a minimum period of 18 months. Beyond the demographic data collection, patients were evaluated according to the arthroscopic classification of Baker et al., the Disabilities of the Arm, Shoulder, and Hand (DASH questionnaire and the Mayo Elbow Performance Score (MEPS. The patients' ages ranged between 23 and 56 years (average 46 years (eight males and six females. Of the 15 elbows, 12 were the dominant and one patient had bilateral lesion. The follow-up after surgery was minimum 24 months and maximum 72 months (average 41 months. Results: we found, according to the arthroscopic classification of Baker et al., two patients with type I lesions, nine with type II lesions and three with type III lesions. We found the following complications: one patient with altered sensitivity in the region of the lateral portal, one with a deficit of ten degrees in length, one with synovial plica and one with synovitis in the lateral compartment. Our score on the DASH questionnaire was minimum of 32 points and maximum of 120 points (average 57 points and the scale of MEPS had a minimum score of 60 points and a maximum of 100 points (average 90 points. Conclusion: the arthroscopic treatment of the lateral epicondylitis, plus insurance, provides satisfactory results.

Performance evaluation of early maize genotypes in far western hills of Nepal

Directory of Open Access Journals (Sweden)

Hari Kumar Prasai

2015-12-01

Full Text Available Initial evaluation trial of maize (early genotypes was carried out at Regional Agricultural Research Station, Doti, Nepal in 2013 and 2014. Total fourteen and fifteen genotypes of early maize were included in initial evaluation experiment of the year 2013 and 2014 respectively. The experiment was laid out in randomized complete block design (RCBD with three replications in each year. Out of the tested genotypes, SO3TEY/LN, ZM 423 and SO3TEY-FM (ER identified as promising from statistical analysis over year. All the tested characters were found statistically significant. Similarly, the coordinated varietal trial of maize (early was also carried out in the same station at 2013 and 2014. Total fourteen genotypes in 2013 and fifteen genotypes in 2015 of maize (early were included in the experiment. The RCB design was applied and the experiment was replicated three times in every year. ZM 627 and ZM 621/Pool -15 genotypes identified as superior next to Arun-2 from the analysis of two year data. All the tested traits were found statistically significant in over year analysis.

Smartphone-based evaluations of clinical placements—a useful complement to web-based evaluation tools

Directory of Open Access Journals (Sweden)

Jesper Hessius

2015-11-01

Full Text Available Purpose: Web-based questionnaires are currently the standard method for course evaluations. The high rate of smartphone adoption in Sweden makes possible a range of new uses, including course evaluation. This study examines the potential advantages and disadvantages of using a smartphone app as a complement to web-based course evaluationsystems. Methods: An iPhone app for course evaluations was developed and interfaced to an existing web-based tool. Evaluations submitted using the app were compared with those submitted using the web between August 2012 and June 2013, at the Faculty of Medicine at Uppsala University, Sweden. Results: At the time of the study, 49% of the students were judged to own iPhones. Over the course of the study, 3,340 evaluations were submitted, of which 22.8% were submitted using the app. The median of mean scores in the submitted evaluations was 4.50 for the app (with an interquartile range of 3.70-5.20 and 4.60 (3.70-5.20 for the web (P=0.24. The proportion of evaluations that included a free-text comment was 50.5% for the app and 49.9% for the web (P=0.80. Conclusion: An app introduced as a complement to a web-based course evaluation system met with rapid adoption. We found no difference in the frequency of free-text comments or in the evaluation scores. Apps appear to be promising tools for course evaluations. web-based course evaluation system met with rapid adoption. We found no difference in the frequency of free-text comments or in the evaluation scores. Apps appear to be promising tools for course evaluations.

Smartphone-based evaluations of clinical placements-a useful complement to web-based evaluation tools.

Science.gov (United States)

Hessius, Jesper; Johansson, Jakob

2015-01-01

Web-based questionnaires are currently the standard method for course evaluations. The high rate of smartphone adoption in Sweden makes possible a range of new uses, including course evaluation. This study examines the potential advantages and disadvantages of using a smartphone app as a complement to web-based course evaluationsystems. An iPhone app for course evaluations was developed and interfaced to an existing web-based tool. Evaluations submitted using the app were compared with those submitted using the web between August 2012 and June 2013, at the Faculty of Medicine at Uppsala University, Sweden. At the time of the study, 49% of the students were judged to own iPhones. Over the course of the study, 3,340 evaluations were submitted, of which 22.8% were submitted using the app. The median of mean scores in the submitted evaluations was 4.50 for the app (with an interquartile range of 3.70-5.20) and 4.60 (3.70-5.20) for the web (P=0.24). The proportion of evaluations that included a free-text comment was 50.5% for the app and 49.9% for the web (P=0.80). An app introduced as a complement to a web-based course evaluation system met with rapid adoption. We found no difference in the frequency of free-text comments or in the evaluation scores. Apps appear to be promising tools for course evaluations. web-based course evaluation system met with rapid adoption. We found no difference in the frequency of free-text comments or in the evaluation scores. Apps appear to be promising tools for course evaluations.

12 CFR 516.110 - Who may submit a written comment?

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Who may submit a written comment? 516.110 Section 516.110 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY APPLICATION PROCESSING PROCEDURES Comment Procedures § 516.110 Who may submit a written comment? Any person may submit a...

A probability evaluation method of early deterioration condition for the critical components of wind turbine generator systems

DEFF Research Database (Denmark)

Hu, Y.; Li, H.; Liao, X

2016-01-01

method of early deterioration condition for critical components based only on temperature characteristic parameters. First, the dynamic threshold of deterioration degree function was proposed by analyzing the operational data between temperature and rotor speed. Second, a probability evaluation method...... of early deterioration condition was presented. Finally, two cases showed the validity of the proposed probability evaluation method in detecting early deterioration condition and in tracking their further deterioration for the critical components.......This study determines the early deterioration condition of critical components for a wind turbine generator system (WTGS). Due to the uncertainty nature of the fluctuation and intermittence of wind, early deterioration condition evaluation poses a challenge to the traditional vibration...

Performance of Commercial Laying Hen Submitted to Different Debeaking Methods

Directory of Open Access Journals (Sweden)

CH Oka

Full Text Available ABSTRACT Among the several factors required in breeding laying hens, debeaking is a factor that interferes with batch performance and affects animal welfare. Thus, the objective of this study was to evaluate three different debeaking procedures and to verify the best technique to be used. For this, the performance of the birds, the incidence of cannibalism, and in rearing phase, the quality of the eggs were evaluated. Dekalb White birds were distributed in a completely randomized design with three treatments, T1 (infrared radiation debeaking T2 (hot blade debeaking and T3 (V debeaking.The data was submitted to Analysis of Variance and compared by Tukey’s test (95%, using statistical software R. The frequencies of mortality and cannibalism were submitted to the Chi-Square test (Software R. It was observed that mortality was lower with IR debeaking in the breeding phase. Already in the rearing phase, the mortality was similar between the debeaking techniques and the cannibalism was null. The final mean weight (g, mean weight gain (g and average daily weight gain in the rearing and egg quality variables were higher for V debeaking when compared to other techniques. It is concluded that V-debeaking provides better bird performance, resistance and shell thickness when compared to the infrared radiations and hot blade debeaking, in addition to subjecting the birds to less stress.

Physiological responses of cacharas Pseudoplatystoma reticulatum submitted to natural anesthetics

Directory of Open Access Journals (Sweden)

Milena Souza dos Santos Sanchez

2014-02-01

Full Text Available The present study the aimed to evaluate the induction time, recovery time and physiological responses of cacharas, Pseudoplatystoma reticulatum, submitted to eugenol and menthol. 42 cacharas were exposed to eugenol 100 mgL-1 (n=14 and menthol 150 mgL-1 (n=14 and the control group (n=14 which were not exposed to any anesthetics. At the time 0 and 24 hours after induction, the bloods of 7 fishes per treatment were collected to measure the hematologic parameters and plasma glucose evaluation. The recovery was conducted in aquariums free of anesthetic, and induction and recovery times were monitored. The results were submitted to analysis of variance (P0.05 for induction time, however the recovery time had a significant reduction (P<0.05 for the menthol 150 mgL-1. There was no treatment effects on hematologic parameters, except for mean corpuscular volume (VCM, which was observed an interaction effect between factors, once fish anesthetized with eugenol showed significant reduction (P<0.05 on VCM 24 hours after anesthesia. Plasma glucose values did not differ at 0 hour after induction. 24 hours after induction, both control group and fishes exposed to eugenol and menthol were significantly reduce in VCM. Eugenol at 100 mgL-1 and menthol at 150 mgL-1 may be safely induced in cachara during biometrics procedures.

29 CFR 4010.13 - Confidentiality of information submitted.

Science.gov (United States)

2010-07-01

... REPORTING AND DISCLOSURE REQUIREMENTS ANNUAL FINANCIAL AND ACTUARIAL INFORMATION REPORTING § 4010.13 Confidentiality of information submitted. In accordance with § 4901.21(a)(3) of this chapter and ERISA section... 29 Labor 9 2010-07-01 2010-07-01 false Confidentiality of information submitted. 4010.13 Section...

A protocol of a cross-sectional study evaluating an online tool for early career peer reviewers assessing reports of randomised controlled trials.

Science.gov (United States)

Chauvin, Anthony; Moher, David; Altman, Doug; Schriger, David L; Alam, Sabina; Hopewell, Sally; Shanahan, Daniel R; Recchioni, Alessandro; Ravaud, Philippe; Boutron, Isabelle

2017-09-15

Systematic reviews evaluating the impact of interventions to improve the quality of peer review for biomedical publications highlighted that interventions were limited and have little impact. This study aims to compare the accuracy of early career peer reviewers who use an innovative online tool to the usual peer reviewer process in evaluating the completeness of reporting and switched primary outcomes in completed reports. This is a cross-sectional study of individual two-arm parallel-group randomised controlled trials (RCTs) published in the BioMed Central series medical journals, BMJ , BMJ Open and Annals of Emergency Medicine and indexed with the publication type 'Randomised Controlled Trial'. First, we will develop an online tool and training module based (a) on the Consolidated Standards of Reporting Trials (CONSORT) 2010 checklist and the Explanation and Elaboration document that would be dedicated to junior peer reviewers for assessing the completeness of reporting of key items and (b) the Centre for Evidence-Based Medicine Outcome Monitoring Project process used to identify switched outcomes in completed reports of the primary results of RCTs when initially submitted. Then, we will compare the performance of early career peer reviewers who use the online tool to the usual peer review process in identifying inadequate reporting and switched outcomes in completed reports of RCTs at initial journal submission. The primary outcome will be the mean number of items accurately classified per manuscript. The secondary outcomes will be the mean number of items accurately classified per manuscript for the CONSORT items and the sensitivity, specificity and likelihood ratio to detect the item as adequately reported and to identify a switch in outcomes. We aim to include 120 RCTs and 120 early career peer reviewers. The research protocol was approved by the ethics committee of the INSERM Institutional Review Board (21 January 2016). The study is based on voluntary

Sensory evaluation of black beans submitted to gamma radiation from Cobalt-60; Avaliacao sensorial de feijao preto submetido a radiacao de Cobalto-60

Energy Technology Data Exchange (ETDEWEB)

Moura, Neila Camargo de; Canniatti-Brazaca, Solange Guidolin; Spoto, Marta Helena Fillet, E-mail: sgcbraza@esalq.usp.b [Escola Superior de Agricultura Luiz de Queiroz (ESALQ/USP), Piracicaba, SP (Brazil). Dept. de Agroindustria, Alimentos e Nutricao; Arthur, Valter [Centro de Energia Nuclear na Agricultura (CENA/USP), Piracicaba, SP (Brazil). Secao de Entomologia e Irradiacao de Alimentos

2005-04-15

The objective of this research was to evaluate the sensory aspects of black beans submitted to gamma radiation from {sup 60}Co. The study involved eight panelists, between 17 to 23 years old, who were selected and trained for the descriptive analysis of appearance, aroma, flavor and texture. The panelists analyzed alterations of appearance, aroma, flavor and texture of non-irradiated and irradiated black beans with doses 2, 4, 6, 8 and 10kGy. The results were analyzed by test F, ANOVA and the Tukey test (5%), with the use of computers and the sensory analysis software Compusense Five and SAS. The results showed that irradiated samples decreased the bitter flavor, accentuated color and brightness and samples non-irradiated dry texture. The radiation treatment is a good method for conservation of black beans in doses evaluated in this study.(author)

Radiological evaluation of early gastric cancer: analysis of 104 cases

International Nuclear Information System (INIS)

Choi, Byung Ihn; Kim, Jae Hyung; Han, Man Chung

1987-01-01

During the two year period from January 1985 to December 1986, 161 cases were confirmed as early gastric cancer by pathologic mapping at Seoul National University Hospital. Among them, the authors reviewed 104 cases of early gastric cancer for the evaluation of diagnostic value of double contrast upper gastrointestinal series. Early gastric cancer was most common in 5th and 6th decade (64%) and male to female ratio was 2:1. Double contrast upper GI series could detect 97 out of 104 cases (93%). Among them, 62 cases were diagnosed as early gastric cancer, 32 as advanced gastric cancer and 3 as benign lesion. Detection rate according to the size was 100% in lesion larger than 2cm and 87% in lesion smaller than 2cm. Predictability of early gastric cancer according to size was 66% in lesion smaller than 3cm and 43% in lesion larger than 3cm. Detection rate according to the location of the tumor was almost similar between gastric body (94%) and antrum (93%), however was very low in anterior wall lesion (70%). Predictability of early gastric cancer was 69% in gastric body lesion, 52% in gastric antral lesion and 44% in greater curvature lesion. Detection rate according to the type of macrospecimen was 100% in type I, III and IIc+III. Type IIb showed the lowest detection rate (75%). Predictability of early gastric cancer was high in type IIc (68%) and low in type I (20%)

Production aspects of broiler breeders submitted to different drinker types

Directory of Open Access Journals (Sweden)

LP Colvero

2014-03-01

Full Text Available The objective of this study was of evaluate the influence of different drinker types on the egg production, water intake, mortality, poultry litter relative humidity, egg weight, eggshell percentage, and egg specific gravity of broiler breeders. The experiment was carried out in a commercial farm with 37- to 44-wk-old broiler breeders. A randomized block experimental design, consisting of two treatments (bell or nipple drinkers with four replicates of 4.000 females each, was applied. Data were submitted to analysis of variance, and means were compared by the test of Student-Newman-Keuls at 5% significance level. Birds submitted to nipple drinkers presented lower water intake (p0.05 of drinker type on egg production or mortality. Poultry litter relative humidity was lower (p<0.05 under the nipple-drinker system. Birds drinking from bell drinkers produced heavier eggs (p<0.05 between weeks 39 and 40. Hens drinking from bell drinkers laid eggs with higher specific gravity and eggshell percentage. It was concluded that nipple drinkers can be used for broiler breeders during lay.

30 CFR 285.607 - How do I submit my SAP?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I submit my SAP? 285.607 Section 285.607... Assessment Plan and Information Requirements for Commercial Leases § 285.607 How do I submit my SAP? You must submit one paper copy and one electronic version of your SAP to MMS at the address listed in § 285.110(a). ...

A Checklist for Submitting Your Risk Management Plan (RMP)

Science.gov (United States)

Important information about 2014 submissions and a checklist to consider in preparing and resubmitting a 5-year update, as required by 40 CFR part 68. Use the RMP*eSubmit software application, which replaced RMP*Submit.

42 CFR 405.809 - Opportunity to submit evidence.

Science.gov (United States)

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Opportunity to submit evidence. 405.809 Section 405.809 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM FEDERAL HEALTH INSURANCE FOR THE AGED AND DISABLED Appeals Under the Medicare Part B Program § 405.809 Opportunity to submit...

Evaluation of flaxseed effects on non-alcoholic fatty liver disease (NAFLD in rabbits submitted to a hypercholesterolemic diet

Directory of Open Access Journals (Sweden)

Caroline Tatim Saad

2014-10-01

Full Text Available Background: The aim of the present study is to evaluate the role of flaxseed in non-alcoholic fatty liver disease, as well as on the lipid profile in rabbits submitted to hypercholesterolemic diet. Subject and Methods: 32 male rabbits, weighing approximately 1.5kg and averaging four months of age, were distributed into three groups. Group 1 received standard food plus 0.5% of cholesterol from dried egg, during 8 weeks. Group 2 obtained the same diet in the first 4 weeks, and 8mg/kg of ground flaxseed was added in the remaining weeks. Lastly, group 3 was fed with the previous group’s increased diet throughout the entire period. In the follow-up, the animals were euthanized, and liver blades were prepared to evaluate the histopathologic study. The evaluation score of NAFLD (ESN, as well as plasma levels of total cholesterol, LDLcholesterol, HDL-cholesterol, triglycerides and body weight, were all determined. Results: Increased levels of total cholesterol were obtained in both groups, with the smallest variation found in G3 (p=0.002. This variation was also found when the levels of LDLcholesterol were assessed (p=0.001. There was a reduction of triglyceride levels at the end of the study in G3 (p=0.008. A variation was noticed between the ESN groups, but the induced reduction was not statistically significant. Conclusion: Further studies are necessary, in order to elucidate the effects of flaxseed in NAFLD as well as in diseases that have risk factors for the development of the disease

Obese patients with type 2 diabetes submitted to banded gastric bypass: greater incidence of dumping syndrome.

Science.gov (United States)

Padoin, Alexandre Vontobel; Galvão Neto, Manoel; Moretto, Myriam; Barancelli, Fabiano; Schroer, Caroline Eckerdt; Mottin, Cláudio Corá

2009-11-01

Dumping syndrome is one of ten most common complications in morbidly obese patients operated. Recent studies in relation to type 2 diabetes mellitus (DM2) in patients submitted to gastric bypass led us to examine the different outcomes in this group of patients. Our objective was to determine the difference in the prevalence of dumping syndrome in patients with DM2 submitted to gastric bypass. In this retrospective study, 49 diabetic and 54 non-diabetic morbidly obese patients were submitted to gastric bypass and followed up at 3, 6, and 12 months after surgery. The occurrence of dumping was determined by the patient's medical chart, where it was considered positive if recorded in at least one of three evaluations. The 103 patients evaluated had a mean BMI of 49.5 +/- 9.3 kg/m(2) and mean age of 38 +/- 9.7 years, with 75.7% being women. The prevalence of dumping syndrome in this population was 24.3%. The prevalence of dumping was greater in patients with DM2 (44.9%) when compared to the control group (5.6%; p DM2 as the only variable associated with dumping syndrome. Dumping syndrome is a common postoperative complication in gastric bypass. Patients with DM2 show a greater postoperative prevalence of dumping.

An evaluation of the Triage Early Warning Score in an urban ...

African Journals Online (AJOL)

2013-12-03

Dec 3, 2013 ... Original Research: An evaluation of the Triage Early Warning Score in an urban accident and emergency department. 69 ... This can potentially improve the gap .... were defined as “discharge within 24 hours of admission,.

Evaluation of entrance surface-skin doses in animals submitted on exams of abdomen in veterinary radiology using Tl dosimetry

International Nuclear Information System (INIS)

Veneziani, G. R.; Matsushima, L. C.; Campos, L. L.; Filho, A. M.

2014-08-01

The radiation protection has recently gained considerable attention in human medicine. In veterinary medicine has been some advances in radiodiagnostic and therapy for domestic animal like dogs and cats. It is notable the increase of the costs with domestic animals that are considered, by many people in the whole world, like members of family. However, an important parameter that must be taken into account is the increasing use of computed tomography and other equipment s that uses ionizing radiation, which may lead to comparatively high exposure of critical organs. The radiation dose is determined by the balance between therapeutic benefit and possible damage to surrounding normal tissues. This study aimed the evaluation of entrance surface-skin doses in dogs submitted to radiodiagnostic procedures of abdomen using the technique of thermoluminescent dosimetry (TLD). The radiation doses were measured using thermoluminescent dosimeters of LiF:Mg,Ti (TLD 100) and a dog phantom made with a plastic container, proportional to the dog size, fulfilled with water. (Author)

Evaluation of entrance surface-skin doses in animals submitted on exams of abdomen in veterinary radiology using Tl dosimetry

Energy Technology Data Exchange (ETDEWEB)

Veneziani, G. R.; Matsushima, L. C.; Campos, L. L. [Instituto de Pesquisas Energeticas e Nucleares, Gerencia de Metrologia das Radiacoes / CNEN, Av. Lineu Prestes 2242, Cidade Universitaria, 05508-000 Sao Paulo (Brazil); Filho, A. M., E-mail: venezianigr@gmail.com [Centro Universitario de Rio Petro - UNIRP, Rodovia Br 153 (Transbrasiliana), Km. 69 Sao Jose do Rio Preto, Sao Paulo (Brazil)

2014-08-15

The radiation protection has recently gained considerable attention in human medicine. In veterinary medicine has been some advances in radiodiagnostic and therapy for domestic animal like dogs and cats. It is notable the increase of the costs with domestic animals that are considered, by many people in the whole world, like members of family. However, an important parameter that must be taken into account is the increasing use of computed tomography and other equipment s that uses ionizing radiation, which may lead to comparatively high exposure of critical organs. The radiation dose is determined by the balance between therapeutic benefit and possible damage to surrounding normal tissues. This study aimed the evaluation of entrance surface-skin doses in dogs submitted to radiodiagnostic procedures of abdomen using the technique of thermoluminescent dosimetry (TLD). The radiation doses were measured using thermoluminescent dosimeters of LiF:Mg,Ti (TLD 100) and a dog phantom made with a plastic container, proportional to the dog size, fulfilled with water. (Author)

Casemix and rehabilitation: evaluation of an early discharge scheme.

Science.gov (United States)

Brandis, S

2000-01-01

This paper presents a case study of an early discharge scheme funded by casemix incentives and discusses limitations of a casemix model of funding whereby hospital inpatient care is funded separately from care in other settings. The POSITIVE Rehabilitation program received 151 patients discharged early from hospital in a twelve-month period. Program evaluation demonstrates a 40.9% drop in the average length of stay of rehabilitation patients and a 42.6% drop in average length of stay for patients with stroke. Other benefits of the program include a high level of patient satisfaction, improved carer support and increased continuity of care. The challenge under the Australian interpretation of a casemix model of funding is ensuring the viability of services that extend across acute hospital, non-acute care, and community and home settings.

Bond strength of resin-resin interfaces contaminated with saliva and submitted to different surface treatments

DEFF Research Database (Denmark)

Furuse, Adilson Yoshio; da Cunha, Leonardo Fernandes; Benetti, Ana Raquel

2007-01-01

of silane and adhesive system. Resin cylinders were placed over the treated surfaces. The specimens were stored in water or ethanol. Shear bond strength tests were performed and the mode of failure was evaluated. Data were submitted to two-way ANOVA and Dunnett T3 test. Contamination of resin...

30 CFR 218.580 - When do I submit Form MMS-4444?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When do I submit Form MMS-4444? 218.580 Section 218.580 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE... Correspondence § 218.580 When do I submit Form MMS-4444? Initially, you must submit MMS Form-4444 by November 29...

Detailed evaluation of ET-RR-2 neutronic design: approach to criticality

International Nuclear Information System (INIS)

Ashoub, N.; Amin, E.

2000-01-01

The ET-RR-2 safety analysis evaluation effort included the assessment of the reactor core nuclear design parameters. The present work complements the previous effort of neutronic calculations using NCNSRC computer code packages. This paper is the first in comprehensive neutronic calculation assessment up to the equilibrium core. It deals with evaluation of neutronic calculation submitted during the early phase of the licensing process; namely the proposal to assemble the first critical core, calculation of power peaking factor and determination of detailed energy group flux distribution in the core particularly in the cobalt irradiation position. The neutronic design criteria are examined qualitatively and quantitatively in the present paper

Retrospective evaluation of positional movements of patients with prostate cancer submitted to IGRT (radiotherapy guided by image)

International Nuclear Information System (INIS)

Rocha, N.K.S.; Filipov, D.; Soboll, D.S.

2017-01-01

It is a retrospective study that analyzed positional fluctuations of 29 patients submitted to prostate radiotherapy, using IGRT. The minimum and maximum averages of the lateral, longitudinal and vertical displacements were calculated, obtaining a general average of the displacements that remained close to zero and one the most evident variation between the lateral and vertical axes

Exercise through a cardiac rehabilitation program attenuates oxidative stress in patients submitted to coronary artery bypass grafting.

Science.gov (United States)

Taty Zau, José Francisco; Costa Zeferino, Rodrigo; Sandrine Mota, Nádia; Fernandes Martins, Gerez; Manoel Serra, Salvador; Bonates da Cunha, Therezil; Medeiros Lima, Daniel; Bragança Pereira, Basilio de; Matos do Nascimento, Emília; Filho, Danilo Wilhelm; Curi Pedrosa, Rozangela; Pedrosa, Roberto Coury

2018-12-01

Cardiovascular disease is the main cause of morbidity and mortality in the world and oxidative stress has been implicated in the pathogenesis. Cardiac rehabilitation in patients with coronary artery disease submitted to coronary artery bypass grafting may prevent cardiovascular events probably through the attenuation of oxidative stress. The aim of this study was to evaluate the benefits of a cardiac rehabilitation program in the control of the systemic oxidative stress. The studied population consisted of 40 patients, with chronic stable coronary artery disease submitted to coronary artery bypass grafting, who attended a cardiac rehabilitation program. Biomarkers of oxidative stress were evaluated in the blood of these patients at different moments. After the onset of cardiac rehabilitation, there was a significant and progressive decrease in thiobarbituric acid reactive substances levels and protein carbonyls, an initial increase and subsequent decrease in superoxide dismutase, catalase and glutathione peroxidase activities. Also, a progressive increase of uric acid, while ferric reducing antioxidant power levels increased only at the end of the cardiac rehabilitation and a tendency to increase of glutathione contents. The results suggest that regular exercise through a cardiac rehabilitation program can attenuate oxidative stress in chronic coronary artery disease patients submitted to coronary artery bypass grafting.

33 CFR 160.210 - Methods for submitting an NOA.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Methods for submitting an NOA... Conditions, and Certain Dangerous Cargos § 160.210 Methods for submitting an NOA. (a) Submission to the... the NVMC web site at http://www.nvmc.uscg.gov; (ii) Electronic submission of Extensible Markup...

Causes of mortality of wild birds submitted to the Charles Darwin Research Station, Santa Cruz, Galapagos, Ecuador from 2002-2004.

Science.gov (United States)

Gottdenker, Nicole L; Walsh, Timothy; Jiménez-Uzcátegui, Gustavo; Betancourt, Franklin; Cruz, Marilyn; Soos, Catherine; Miller, R Eric; Parker, Patricia G

2008-10-01

Necropsy findings were reviewed from wild birds submitted to the Charles Darwin Research Station, Santa Cruz Island, Galápagos Archipelago between 2004 and 2006. One hundred and ninety cases from 27 different species were submitted, and 178 of these cases were evaluated grossly or histologically. Trauma and trauma-related deaths (n=141) dominated necropsy submissions. Infectious causes of avian mortality included myiasis due to Philornis sp. (n=6), avian pox (n=1), and schistosomosis (n=1).

Evaluation of nectar of kiwi (Actinidia deliciosa) submitted to gamma radiation

International Nuclear Information System (INIS)

Harder, Marcia N C.; Toledo, Tais C.F. de; Ferreira, Andrea C.P.; Arthur, Valter

2007-01-01

The kiwi is an exotic fruit, it is pertaining the Actinidaceae family, possesses high nutritional value, being rich mainly in vitamin C and fibers, calcium, iron and phosphorus, what turns it a good nutritious option, presenting an important associated attribute the quality of the fruits and the flavor, what be comes it a fruit with great acceptance in the consuming markets, mainly children. The irradiation is an excellent method of conservation, as well as an accomplice to reinforce the action of other applied processes with the same purpose. The objective of this work was to formulate a sweetened drink, no alcoholic, starting from the kiwi (Actinidia deliciosa), to submit its at the gamma radiation for source of Co 60 with doses of: 0 (control); 0.5; 1.0 and 2.0 kGy in a tax of dose of 0.712 kGy/hour, and subsequent physiochemical and sensorial analyses for detection of possible alterations provoked by the radiation. It is possible to conclude that the radiation in the doses used did not promote significant alterations in the physiochemical and sensorial characteristics of the kiwi nectar. (author)

Evaluation of nectar of kiwi (Actinidia deliciosa) submitted to gamma radiation

Energy Technology Data Exchange (ETDEWEB)

Harder, Marcia N C.; Toledo, Tais C.F. de; Ferreira, Andrea C.P.; Arthur, Valter [Centro de Energia Nuclear na Agricultura (CENA), Piracicaba, SP (Brazil). Lab. de Irradiacao de Alimentos e Radioentomologia]. E-mails: mnharder@cena.usp.br; tcftoled@cena.usp.br; andrea@dtr.com.br; arthur@cena.usp.br; Spoto, Marta H.F. [Escola Superior de Agricultura Luiz de Queiroz(ESALQ/USP), Piracicaba, SP (Brazil)]. E-mail: mhfspoto@esalq.usp.br

2007-07-01

The kiwi is an exotic fruit, it is pertaining the Actinidaceae family, possesses high nutritional value, being rich mainly in vitamin C and fibers, calcium, iron and phosphorus, what turns it a good nutritious option, presenting an important associated attribute the quality of the fruits and the flavor, what be comes it a fruit with great acceptance in the consuming markets, mainly children. The irradiation is an excellent method of conservation, as well as an accomplice to reinforce the action of other applied processes with the same purpose. The objective of this work was to formulate a sweetened drink, no alcoholic, starting from the kiwi (Actinidia deliciosa), to submit its at the gamma radiation for source of Co{sup 60} with doses of: 0 (control); 0.5; 1.0 and 2.0 kGy in a tax of dose of 0.712 kGy/hour, and subsequent physiochemical and sensorial analyses for detection of possible alterations provoked by the radiation. It is possible to conclude that the radiation in the doses used did not promote significant alterations in the physiochemical and sensorial characteristics of the kiwi nectar. (author)

30 CFR 218.560 - How do I submit Form MMS-4444?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I submit Form MMS-4444? 218.560 Section... Correspondence § 218.560 How do I submit Form MMS-4444? A copy of Form MMS-4444 and instructions may be obtained from MMS. It will also be posted on the MMS Web site. Submit the completed, signed form to the address...

Effects of mild running on substantia nigra during early neurodegeneration.

Science.gov (United States)

Almeida, Michael F; Silva, Carolliny M; Chaves, Rodrigo S; Lima, Nathan C R; Almeida, Renato S; Melo, Karla P; Demasi, Marilene; Fernandes, Tiago; Oliveira, Edilamar M; Netto, Luis E S; Cardoso, Sandra M; Ferrari, Merari F R

2018-06-01

Moderate physical exercise acts at molecular and behavioural levels, such as interfering in neuroplasticity, cell death, neurogenesis, cognition and motor functions. Therefore, the aim of this study is to analyse the cellular effects of moderate treadmill running upon substantia nigra during early neurodegeneration. Aged male Lewis rats (9-month-old) were exposed to rotenone 1mg/kg/day (8 weeks) and 6 weeks of moderate treadmill running, beginning 4 weeks after rotenone exposure. Substantia nigra was extracted and submitted to proteasome and antioxidant enzymes activities, hydrogen peroxide levels and Western blot to evaluate tyrosine hydroxylase (TH), alpha-synuclein, Tom-20, PINK1, TrkB, SLP1, CRMP-2, Rab-27b, LC3II and Beclin-1 level. It was demonstrated that moderate treadmill running, practiced during early neurodegeneration, prevented the increase of alpha-synuclein and maintained the levels of TH unaltered in substantia nigra of aged rats. Physical exercise also stimulated autophagy and prevented impairment of mitophagy, but decreased proteasome activity in rotenone-exposed aged rats. Physical activity also prevented H 2 O 2 increase during early neurodegeneration, although the involved mechanism remains to be elucidated. TrkB levels and its anterograde trafficking seem not to be influenced by moderate treadmill running. In conclusion, moderate physical training could prevent early neurodegeneration in substantia nigra through the improvement of autophagy and mitophagy.

30 CFR 210.101 - Who must submit production reports?

Science.gov (United States)

2010-07-01

... MANAGEMENT FORMS AND REPORTS Production Reports-Oil and Gas § 210.101 Who must submit production reports? (a... operator number. To obtain an operator number, refer to the MMS Minerals Production Reporter Handbook for... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Who must submit production reports? 210.101...

Fracture resistance of teeth submitted to several internal bleaching protocols.

Science.gov (United States)

Leonardo, Renato de Toledo; Kuga, Milton Carlos; Guiotti, Flávia Angélica; Andolfatto, Carolina; Faria-Júnior, Norberto Batista de; Campos, Edson Alves de; Keine, Kátia Cristina; Dantas, Andrea Abi Rached

2014-03-01

The aim of this study was to evaluate the fracture resistance of teeth submitted to several internal bleaching protocols using 35% hydrogen peroxide (35HP), 37% carbamide peroxide (37CP), 15% hydrogen peroxide with titanium dioxide nanoparticles (15HPTiO2) photoactivated by LED-laser or sodium perborate (SP). After endodontic treatment, fifty bovine extracted teeth were divided into five groups (n = 10): G1-unbleached; G2-35HP; G3-37CP; G4-15HPTiO2 photoactivated by LED-laser and G5-SP. In the G2 and G4, the bleaching protocol was applied in 4 sessions, with 7 days intervals between each session. In the G3 and G5, the materials were kept in the pulp teeth for 21 days, but replaced every 7 days. After 21 days, the teeth were subjected to compressive load at a cross head speed of 0.5 mm/min, applied at 135° to the long axis of the root using an eletromechanical testing machine, until teeth fracture. The data were submitted to ANOVA and Tukey tests (α = 5%). The 35HP, 37CP, 15HPTiO2 and SP showed similar fracture resistance teeth reduction (p > 0.05). All bleaching treatments reduced the fracture resistance compared to unbleached teeth (p endodontically-treated teeth, but there were no differences between each other. There are several internal bleaching protocols using hydrogen peroxide in different concentrations and activation methods. This study evaluated its effects on fracture resistance in endodontically-treated teeth.

40 CFR 60.2900 - When must I submit my waste management plan?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Waste Management Plan § 60.2900 When must I submit my waste management plan? You must submit a waste management plan prior to commencing construction, reconstruction, or modification. ...

40 CFR 62.14715 - When must I submit my waste management plan?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 8 2010-07-01 2010-07-01 false When must I submit my waste management... submit my waste management plan? You must submit the waste management plan no later than April 5, 2004. ... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That...

76 FR 9583 - Draft Guidance for Industry on Clinical Pharmacogenomics: Premarketing Evaluation in Early Phase...

Science.gov (United States)

2011-02-18

... final version of the guidance, submit either electronic or written comments on the draft guidance by... electronic access to the guidance document. Submit electronic comments on the draft guidance to http://www... body tissue or fluid (e.g., blood, plasma, cerebrospinal fluid). Drug response results from the...

40 CFR 60.2060 - When must I submit my waste management plan?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Management Plan § 60.2060 When must I submit my waste management plan? You must submit a waste management... Commercial and Industrial Solid Waste Incineration Units for Which Construction Is Commenced After November...

45 CFR 2523.110 - Can Federal agencies submit multiple applications?

Science.gov (United States)

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false Can Federal agencies submit multiple applications? 2523.110 Section 2523.110 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION... AMERICORPS PROGRAM ASSISTANCE § 2523.110 Can Federal agencies submit multiple applications? No. The...

40 CFR 60.3011 - When must I submit my waste management plan?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Model Rule-Waste Management Plan § 60.3011 When must I submit my waste management plan? You must submit a waste management plan no later than 60 days following the initial performance test as specified in...

40 CFR 62.14585 - When must I submit my waste management plan?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 8 2010-07-01 2010-07-01 false When must I submit my waste management... Commenced Construction On or Before November 30, 1999 Waste Management Plan § 62.14585 When must I submit my waste management plan? You must submit a waste management plan no later than April 5, 2004. ...

[Buccal manifestations in patients submitted to chemotherapy].

Science.gov (United States)

Hespanhol, Fernando Luiz; Tinoco, Eduardo Muniz Barretto; Teixeira, Henrique Guilherme de Castro; Falabella, Márcio Eduardo Vieira; Assis, Neuza Maria de Souza Picorelli

2010-06-01

Several changes in the oral cavity due to chemotherapy can be observed and can lead to important systemic complications, increasing the time of the patient in hospital and the costs of the treatment as well as affect the quality of life of the patients. The aim of this study was to assess the oral manifestation in patients treated with chemotherapy according to sex, age and tumor type. Data was collected in an oncology hospital in Juiz de Fora, Minas Gerais State, from patients' records that were submitted to oncologic treatment. It was possible to verify that mucositis, associated or not to other type of lesions, was the most common lesion in both sex of all ages (15.5%). Xerostomia and other lesions, such as Candida infection and aphthous lesions, were also present. It is possible to improve the quality of life of the patient during and after anti-neoplastic therapies through a protocol of odontological assistance that includes changes of the oral environment previous to chemotherapy such as profilaxis, caries removal, treatment of periodontal and periapical lesions, oral hygiene instructions, diet orientation and laser therapy. It is very important the insertion of the dentist in the oncologic medical team for the early diagnosis of the oral manifestation and follow-up during treatment time.

Early evaluation of coronary artery bypass grafts: CT or selective angiography

International Nuclear Information System (INIS)

Wilson, P.C.; Gutierrez, O.; Moss, A.

1984-01-01

A prospective study was performed in 27 patients to compare the value of computed tomography and selective angiography in assessing coronary artery graft patency in the early post-operative period. The sensitivity of CT to graft patency was 85% with no falsely patent determinations. Dynamic CT was not found useful in predicting graft stenosis. There were no complications associated with CT studies, and two related to selective angiography. It is concluded that CT is the procedure of choice for graft evaluation in the early post-operative period; but that angiography is mandatory for the assessment of late symptom recurrence. A review is made of the results described in previous series. (orig.)

Results Evaluation in Reduction Rhinoplasty

Directory of Open Access Journals (Sweden)

Arima, Lisandra Megumi

2011-01-01

Full Text Available Introduction: Final results evaluation after rhinoplasty is a not a topic widely studied from the patient's viewpoint. Objective:Evaluate the satisfaction of the patients submitted to reduction rhinoplasty, from the questionnaire Rhinoplasty Outcomes Evaluation (ROE. Method: Longitudinal study, retrospective cut type, of the preoperative and postoperative satisfaction. The sample was composed by 28 patients who were submitted to rhinoplasty and answered the ROE questionnaire. Three variables were obtained: satisfaction note that the patient had with his/her image before the surgery; note of satisfaction with the current appearance; the difference of the average satisfaction notes between postoperative and preoperative approaches. Results: The postoperative note was higher than the preoperative in all patients. We noticed a difference between the average of the postoperative and preoperative of 48.3 (p75 considered to be an excellent outcome (67.9%. Conclusions: The ROE questionnaire is a helpful tool to show the satisfaction of the patient submitted to reduction rhinoplasty. About 92% of the patients submitted to reduction rhinoplasty consider the postoperative result to be good or excellent.

40 CFR 60.2625 - When must I submit my waste management plan?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... or Before November 30, 1999 Model Rule-Waste Management Plan § 60.2625 When must I submit my waste management plan? You must submit a waste management plan no later than the date specified in table 1 of this...

21 CFR 803.13 - Do I need to submit reports in English?

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Do I need to submit reports in English? 803.13... in English? (a) Yes. You must submit all written or electronic equivalent reports required by this part in English. (b) If you submit any reports required by this part in an electronic medium, that...

Report of early site suitability evaluation of the potential repository site at Yucca Mountain, Nevada

International Nuclear Information System (INIS)

Younker, J.L.; Andrews, W.B.; Fasano, G.A.; Herrington, C.C.; Mattson, S.R.; Murray, R.C.; Ballou, L.B.; Revelli, M.A.; Ducharme, A.R.; Shephard, L.E.; Dudley, W.W.; Hoxie, D.T.; Herbst, R.J.; Patera, E.A.; Judd, B.R.; Docka, J.A.; Rickertsen, L.D.

1992-01-01

This study evaluated the technical suitability of Yucca Mountain, Nevada, as a potential site for a mined geologic repository for the permanent disposal of radioactive waste. The evaluation was conducted primarily to determine early in the site characterization program if there are any features or conditions at the site that indicate it is unsuitable for repository development. A secondary purpose was to determine the status of knowledge in the major technical areas that affect the suitability of the site. This early site suitability evaluation (ESSE) was conducted by a team of technical personnel at the request of the Associate Director of the US Department of Energy (DOE) Office of Geologic Disposal, a unit within the DOE's Office of Civilian Radioactive Waste Management. The Yucca Mountain site has been the subject of such evaluations for over a decade. In 1983, the site was evaluated as part of a screening process to identify potentially acceptable sites. The site was evaluated in greater detail and found suitable for site characterization as part of the Environmental Assessment (EA) (DOE, 1986) required by the Nuclear Waste Policy Act of 1982 (NWPA). Additional site data were compiled during the preparation of the Site Characterization Plan (SCP) (DOE, 1988a). This early site suitability evaluation has considered information that was used in preparing both-documents, along with recent information obtained since the EA and SCP were published. This body of information is referred to in this report as ''current information'' or ''available evidence.''

Parent Early Evaluation of Kids: PEEK Outreach Training Project. Final Report.

Science.gov (United States)

Squires, Jane; Twombly, Liz; Yockelson, Sue

This report describes achievements and activities of the Parent Early Evaluation of Kids (PEEK) Outreach Project at the University of Oregon. This project focused on assisting state agencies, regional and tribal entities, and local health and education programs to develop comprehensive, low-cost systems for child-find and referral. Rural and inner…

40 CFR 167.90 - Where to obtain and submit forms.

Science.gov (United States)

2010-07-01

... establishments not found at the same location as their company headquarters, must submit applications and reports... establishments not found at the same location as their company headquarters to be submitted by the company headquarters to the Regional Office having jurisdiction over the State in which the company headquarters is...

A tool for early workstation design for small and medium enterprises evaluated in five cases

NARCIS (Netherlands)

Hallbeck, M.S.; Bosch, T.; Rhijn, J.W.van; Krause, F.; Looze, M.P.de; Vink, P.

2010-01-01

Five case studies on production line design were described to study the effect of an early design support tool. Based on these case studies, the simple, interactive, real-time, medium-fidelity, mixed-reality methodology was not only found to be a good early design stage evaluative tool for

Evaluation and Referral of Children With Signs of Early Puberty.

Science.gov (United States)

Kaplowitz, Paul; Bloch, Clifford

2016-01-01

Concerns about possible early pubertal development are a common cause for referral to pediatric medical subspecialists. Several recent studies have suggested that onset of breast and/or pubic hair development may be occurring earlier than in the past. Although there is a chance of finding pathology in girls with signs of puberty before 8 years of age and in boys before 9 years of age, the vast majority of these children with signs of apparent puberty have variations of normal growth and physical development and do not require laboratory testing, bone age radiographs, or intervention. The most common of these signs of early puberty are premature adrenarche (early onset of pubic hair and/or body odor), premature thelarche (nonprogressive breast development, usually occurring before 2 years of age), and lipomastia, in which girls have apparent breast development which, on careful palpation, is determined to be adipose tissue. Indicators that the signs of sexual maturation may represent true, central precocious puberty include progressive breast development over a 4- to 6-month period of observation or progressive penis and testicular enlargement, especially if accompanied by rapid linear growth. Children exhibiting these true indicators of early puberty need prompt evaluation by the appropriate pediatric medical subspecialist. Therapy with a gonadotropin-releasing hormone agonist may be indicated, as discussed in this report. Copyright © 2016 by the American Academy of Pediatrics.

30 CFR 253.40 - What OSFR evidence must I submit to MMS?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What OSFR evidence must I submit to MMS? 253.40... § 253.40 What OSFR evidence must I submit to MMS? (a) You must submit to MMS: (1) A single demonstration... unaltered Form MMS-1016; (3) MMS forms that identify your COFs (Form MMS-1021, Form MMS-1022), and the...

39 CFR 912.7 - Evidence and information to be submitted.

Science.gov (United States)

2010-07-01

... bearing on either the responsibility of the United States for the death or the damages claimed. (b... and information to be submitted. (a) Death. In support of a claim based on death, the claimant may be required to submit the following evidence or information: (1) An authenticated death certificate or other...

31 CFR 375.12 - How do I submit an offer?

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false How do I submit an offer? 375.12 Section 375.12 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL... way for any unauthorized tender submissions or for any delays, errors, or omissions in submitting...

10 CFR 14.23 - Evidence and information to be submitted.

Science.gov (United States)

2010-01-01

... and death. (8) Any other evidence or information which may have a bearing on either the responsibility... Procedures and Requirements § 14.23 Evidence and information to be submitted. (a) Death. In support of a claim based on death, the claimant may be required to submit the following evidence or information: (1...

76 FR 26223 - Petition for Rulemaking Submitted by Thomas Popik

Science.gov (United States)

2011-05-06

... Rulemaking Submitted by Thomas Popik AGENCY: Nuclear Regulatory Commission. ACTION: Petition for rulemaking... filed with the NRC by Thomas Popik. The petition was docketed by the NRC on March 15, 2011, and has been... received a petition for rulemaking on March 14, 2011 (PRM- 50-96). The petition was submitted by Mr. Thomas...

Evaluating an Enrichment Program in Early Childhood: A Multi-Methods Approach

Science.gov (United States)

van Aswegen, Christa; Pendergast, Donna

2015-01-01

This article reports on the evaluation of one topic in an enrichment program designed for children in their early years of learning. The program is responsive to an increased understanding of the benefits for very young children of programs that not only take advantage of the sensitive periods for learning but that also assist parents to a take a…

Early Evaluation of Response Using 18F-FDG PET Influences Management in Gastrointestinal Stromal Tumor Patients Treated with Neoadjuvant Imatinib.

Science.gov (United States)

Farag, Sheima; Geus-Oei, Lioe-Fee de; van der Graaf, Winette T; van Coevorden, Frits; Grunhagen, Dirk; Reyners, Anna K L; Boonstra, Pieter A; Desar, Ingrid; Gelderblom, Hans; Steeghs, Neeltje

2018-02-01

18 F-FDG PET has previously been proven effective as an early way to evaluate the response of gastrointestinal stromal tumors (GISTs) to imatinib treatment. However, it is unclear whether early evaluation of response affects treatment decisions in GIST patients treated with neoadjuvant intent. Methods: We retrospectively scored changes in management based on early evaluation of response by 18 F-FDG PET in patients in the Dutch GIST registry treated with neoadjuvant imatinib. Results: Seventy 18 F-FDG PET scans were obtained for 63 GIST patients to evaluate for an early response to neoadjuvant imatinib. The scans led to a change in management in 27.1% of the patients. Change in management correlated strongly with lack of metabolic response ( P PET for early evaluation of response often results in a change of management in GIST patients harboring the non- KIT exon 11 mutation and should be considered the standard of care in GIST patients treated with neoadjuvant intent. © 2018 by the Society of Nuclear Medicine and Molecular Imaging.

44 CFR 65.4 - Right to submit new technical data.

Science.gov (United States)

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Right to submit new technical... IDENTIFICATION AND MAPPING OF SPECIAL HAZARD AREAS § 65.4 Right to submit new technical data. (a) A community has..., other than those initiatedby FEMA, must be made in writing by the Chief Executive Officer of the...

37 CFR 2.54 - Requirements for drawings submitted on paper.

Science.gov (United States)

2010-07-01

... submitted on paper. 2.54 Section 2.54 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK... drawings submitted on paper. The drawing must meet the requirements of § 2.52. In addition, in a paper submission, the drawing should: (a) Be on non-shiny white paper that is separate from the application; (b) Be...

15 CFR 325.14 - Submitting reports.

Science.gov (United States)

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Submitting reports. 325.14 Section 325.14 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE MISCELLANEOUS REGULATIONS EXPORT TRADE CERTIFICATES...

Bleaching agent action on color stability, surface roughness and microhardness of composites submitted to accelerated artificial aging.

Science.gov (United States)

Rattacaso, Raphael Mendes Bezerra; da Fonseca Roberti Garcia, Lucas; Aguilar, Fabiano Gamero; Consani, Simonides; de Carvalho Panzeri Pires-de-Souza, Fernanda

2011-04-01

The purpose of this study was to evaluate the bleaching agent action on color stability, surface roughness and microhardness of composites (Charisma, Filtek Supreme and Heliomolar - A2) submitted to accelerated artificial aging (AAA). A Teflon matrix (12 x 2 mm) was used to fabricate 18 specimens (n=6) which, after polishing (Sof-Lex), were submitted to initial color reading (ΔE), Knoop microhardness (KHN) (50 g/15 s load) and roughness (R(a)) (cut-off 0.25 mm) tests. Afterwards, the samples were submitted to AAA for 384 hours and new color, microhardness and roughness readings were performed. After this, the samples were submitted to daily application (4 weeks) of 16% Carbamide Peroxide (NiteWhite ACP) for 8 hours and kept in artificial saliva for 16 hours. New color, microhardness and roughness readings were made at the end of the cycle, and 15 days after bleaching. Comparison of the ΔE means (2-way ANOVA, Bonferroni, P<.05) indicated clinically unacceptable color alteration for all composites after AAA, but without significant difference. Statistically significant increase in the KHN values after AAA was observed, but without significant alterations 15 days after bleaching. For R(a) there was no statistically significant difference after AAA and 15 days after bleaching. The alterations promoted by the bleaching agent and AAA are material dependent.

Evaluation of toxicity reduction of sodium dodecyl sulfate submitted to electron beam radiation

Science.gov (United States)

Romanelli, M. F.; Moraes, M. C. F.; Villavicencio, A. L. C. H.; Borrely, S. I.

2004-09-01

Surfactants, as detergent active substances, are an important source of pollution causing biological adverse effects to aquatic organisms. Several data have been showing ecological disturbance due to the high concentration of surfactants on receiving waters and on wastewater treatment plants. Ionizing radiation has been proved as an effective technology to decompose organic substances and few papers have included ecotoxicological aspects. This paper shows the reduction of acute toxicity of a specific surfactant, sodium dodecyl sulfate (SDS), when diluted in distilled water and submitted to electron beam radiation. The study included two test-organisms, the marine bacteria Vibrio fischeri and the crustacean Daphnia similis. Radiation processing resulted in an important acute toxicity removal for both assays, which can be summarized between 70% and 96%, using 3.0, 6.0, 9.0 and 12.0 kGy as radiation doses. Nevertheless, lower doses demonstrated better effect than 9.0 and 12.0 kGy and the bacterium assay was more sensitive to SDS than crustacean assay.

A randomized controlled trial evaluating early versus traditional oral feeding after colorectal surgery

Directory of Open Access Journals (Sweden)

Ahmet Dag

2011-01-01

Full Text Available OBJECTIVE: This prospective randomized clinical study was conducted to evaluate the safety and tolerability of early oral feeding after colorectal operations. METHODS: A total of 199 patients underwent colorectal surgery and were randomly assigned to early feeding (n = 99 or a regular diet (n = 100. Patients’ characteristics, diagnoses, surgical procedures, comorbidity, bowel movements, defecation, nasogastric tube reinsertion, time of tolerance of solid diet, complications, and length of hospitalization were assessed. RESULTS: The two groups were similar in terms of gender, age, diagnosis, surgical procedures, and comorbidity. In the early feeding group, 85.9% of patients tolerated the early feeding schedule. Bowel movements (1.7±0.89 vs. 3.27±1.3, defecation (3.4±0.77 vs. 4.38±1.18 and time of tolerance of solid diet (2.48±0.85 vs. 4.77±1.81 were significantly earlier in the early feeding group. There was no change between the groups in terms of nasogastric tube reinsertion, overall complication or anastomotic leakage. Hospitalization (5.55±2.35 vs. 9.0±6.5 was shorter in the early feeding group. CONCLUSIONS: The present study indicated that early oral feeding after elective colorectal surgery was not only well tolerated by patients but also affected the postoperative outcomes positively. Early postoperative feeding is safe and leads to the early recovery of gastrointestinal functions.

Probabilistic thinking to support early evaluation of system quality: through requirement analysis

NARCIS (Netherlands)

Rajabali Nejad, Mohammadreza; Bonnema, Gerrit Maarten

2014-01-01

This paper focuses on coping with system quality in the early phases of design where there is lack of knowledge about a system, its functions or its architect. The paper encourages knowledge based evaluation of system quality and promotes probabilistic thinking. It states that probabilistic thinking

Reproductive efficiency of asymptomatic Theileria equi carriers mares submitted to an embryo transfer program

Directory of Open Access Journals (Sweden)

Luciana L. Bezerra

2015-03-01

Full Text Available This study aimed to assess and evaluate the effects of Theileria equi infection on embryonic recovery, gestation and early embryonic loss. Thirteen Mangalarga Marchador Theileria equi positive donors (diagnosed through nested-PCR and 40 embryos receptors were used. Donors were submitted to two embryo collections in two consecutive estrous cycles (GId; after, the same mares were treated with imidocarb dipropionate (1.2mg/kg IM. in order to collect more embryos in two more estrous cycles (GIId. Receptors were divided into two groups (control and with treated with 20 animals each, where one group was the control (GIr and the other one (GIIr treated with 1.2mg/kg IM of imidocarb dipropionate assessing the gestation rate at 15, 30, 45 and 60 days. After 52 embryo collections, the embryonic recovery rates were 53.84% (14/26 and 65.38% (17/26 (p> 0.05 for GId and GIId, respectively. The gestation rate was 70% (14/20 (p>0.05 at 15, 30, 45 and 60 days in group GIr and for GIIr was 85% (17/20 (p>0.05 at 15 days, 80% (16/20 (p>0.05 at 30, 45 and 60 days. The treatment with imidocarb dipropionate did not cause significant improvement in the reproductive efficiency at an ET program.

Evaluation of early efficacy endpoints for proof-of-concept trials.

Science.gov (United States)

Chen, Cong; Sun, Linda; Li, Chih-Lin

2013-03-11

A Phase II proof-of-concept (POC) trial usually uses an early efficacy endpoint other than a clinical endpoint as the primary endpoint. Because of the advancement in bioscience and technology, which has yielded a number of new surrogate biomarkers, drug developers often have more candidate endpoints to choose from than they can handle. As a result, selection of endpoint and its effect size as well as choice of type I/II error rates are often at the center of heated debates in design of POC trials. While optimization of the trade-off between benefit and cost is the implicit objective in such a decision-making process, it is seldom explicitly accounted for in practice. In this research note, motivated by real examples from the oncology field, we provide practical measures for evaluation of early efficacy endpoints (E4) for POC trials. We further provide optimal design strategies for POC trials that include optimal Go-No Go decision criteria for initiation of Phase III and optimal resource allocation strategies for conducting multiple POC trials in a portfolio under fixed resources. Although oncology is used for illustration purpose, the same idea developed in this research note also applies to similar situations in other therapeutic areas or in early-stage drug development in that a Go-No Go decision has to rely on limited data from an early efficacy endpoint and cost-effectiveness is the main concern.

Pullout bond strength of fiber posts luted to different depths and submitted to artificial aging.

Science.gov (United States)

Macedo, V C; Souza, N A Y; Faria e Silva, A L; Cotes, C; da Silva, C; Martinelli, M; Kimpara, E T

2013-01-01

The extension of fiber post cementation often does not seem to influence the fracture resistance of restorations. This study evaluated the effects of cementation depths on the retention of fiber posts submitted to artificial aging. One hundred and sixty bovine incisors were selected to assess post retention. Following endodontic treatment, the canals were flared with diamonds burs. Postholes were prepared in lengths of 5 or 10 mm, after which fiber posts were relined with composite resin and luted with RelyX ARC or RelyX Unicem. The samples were then submitted to thermal and/or mechanical cycling before testing their pullout bond strengths. Absence of cycling was used as a control. The results of each cement were submitted to two-way and post hoc Tukey tests (α=0.05). Independent of the aging protocol, a depth of 10 mm showed higher pullout bond strength than did 5 mm, except for RelyX Unicem without cycling. For RelyX ARC, thermomechanical cycling resulted in lower values than in the absence of cycling. Mechanical cycling alone promoted the highest bond strength when the posts were luted with RelyX Unicem. The effect of artificial aging on the pullout bond strength is dependent on the type of material and the depth.

FLT-PET for early response evaluation of colorectal cancer patients with liver metastases: a prospective study.

Science.gov (United States)

Mogensen, Marie Benzon; Loft, Annika; Aznar, Marianne; Axelsen, Thomas; Vainer, Ben; Osterlind, Kell; Kjaer, Andreas

2017-12-01

Fluoro-L-thymidine (FLT) is a positron emission tomography/computed tomography (PET/CT) tracer which reflects proliferative activity in a cancer lesion. The main objective of this prospective explorative study was to evaluate whether FLT-PET can be used for the early evaluation of treatment response in colorectal cancer patients (CRC) with liver metastases. Patients with metastatic CRC having at least one measurable (>1 cm) liver metastasis receiving first-line chemotherapy were included. A FLT-PET/CT scan was performed at baseline and after the first treatment. The maximum and mean standardised uptake values (SUV max , SUV mean ) were measured. After three cycles of chemotherapy, treatment response was assessed by CT scan based on RECIST 1.1. Thirty-nine consecutive patients were included of which 27 were evaluable. Dropout was mainly due to disease complications. Nineteen patients (70%) had a partial response, seven (26%) had stable disease and one (4%) had progressive disease. A total of 23 patients (85%) had a decrease in FLT uptake following the first treatment. The patient with progressive disease had the highest increase in FLT uptake in SUV max . There was no correlation between the response according to RECIST and the early changes in FLT uptake measured as SUV max (p = 0.24). No correlation was found between early changes in FLT uptake after the first cycle of treatment and the response evaluated from subsequent CT scans. It seems unlikely that FLT-PET can be used on its own for the early response evaluation of metastatic CRC.

28 CFR 54.225 - Educational institutions eligible to submit transition plans.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Educational institutions eligible to submit transition plans. 54.225 Section 54.225 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED... Coverage § 54.225 Educational institutions eligible to submit transition plans. (a) Application. This...

Evaluation of the fuel-element assembly non-hermeticity at its early stage

International Nuclear Information System (INIS)

Bliznyakova, V.A.; Shevel', V.N.; Ostapenko, V.I.

1983-01-01

The given paper deals with control of the fuel-element assembly shell state at the early stage of failure development. Technique for the fuel-element assembly shell state evaluation are described. A method for assembly failure detection, used at WWR of the Institute for Nuclear Research is described also

Burn! How implicit and explicit evaluation predict early adolescents' "hot sauce" aggression towards classroom peers

NARCIS (Netherlands)

Lansu, T.A.M.

2018-01-01

The current study examined to what extent early adolescents' implicit and explicit evaluations of a classmate predict (a) their own aggressive behavior toward that classmate and (b) their classmate's aggressive behavior toward them. Implicit and explicit peer evaluations were assessed among 148

Beyond institutional capacity: political motivation and parliamentary behaviour in the early warning system

NARCIS (Netherlands)

Gattermann, K.; Hefftler, C.

2015-01-01

The Early Warning System gives national parliaments the right to intervene in European Union policy-making. This article investigates their incentives to submit reasoned opinions. It analyses the reactions of 40 parliamentary chambers to 411 draft legislative acts between 1 January 2010 and 31

Hypoparathyroidism after total thyroidectomy: prospective evaluation and relation with early hypocalcemia.

Science.gov (United States)

D'Alessandro, Nicola; Tramutola, Giuseppe; Fasano, Giovanni Michele; Gilio, Francesco; Iside, Giovanni; Izzo, Maria Lucia; Loffredo, Andrea; Pici, Mariano; Pinto, Margherita; Tramontano, Salvatore; Citro, Giuseppe

2016-01-01

Definitive hypoparathyrodism (hypo-PTH) represents one of the most dangerous complication after total thyroidectomy. Partial or total lesion or accidental removal of parathyroid glands is an unpredictable adverse event, although real incidence is not well defined, such as management of this deficit. We started a prospective evaluation of patients treated with total thyroidectomy in our centre, to identify incidence of hypo-PTH, symptomatic or not, in relation to incidence of early postoperative hypocalcemia in our experience. We prospectively evaluated 177 patients treated for benign and malign pathology, measuring calcium before surgery and calcium and PTH at least three months after surgery. Postoperative hypocalcemia was observed in 37.3% of cases. Eight patients (4.5% of cohort) presented low level of PTH, at mean follow-up of 9.1 months. Positive predictive value for postoperative hypocalcemia was 12.1%, while negative predictive was 95.4%; confirming high sensitivity (100%) and low specificity (65.4%) for detecting hypo-PTH. All patients with late hypo-PTH presented hypocalcemia on early analysis, while no case with normal postoperative calcemia accounted with hypo-PTH: this may indicate calcemia as valid prognostic factor of good gland production, when is in the range. Moreover, isolated analysis is too limited to determine real predictability. Technical standardization represents the best method for prevention of hypo-PTH. Early hypocalcemia is a prognostic factor, even with a low specificity, of deficit of PTH-production. This observation must be related to other known prognostic factors. Postoperative normal calcemia should be a positive prognostic factor of an acceptable PTHfunction, supported by large cohorts. Hypocalcemia, Parathormone, Thyroidectomy.

25 CFR 533.2 - Time for submitting management contracts and amendments.

Science.gov (United States)

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Time for submitting management contracts and amendments. 533.2 Section 533.2 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR MANAGEMENT CONTRACT PROVISIONS APPROVAL OF MANAGEMENT CONTRACTS § 533.2 Time for submitting management contracts and...

Intraoperative neurophysiological responses in epileptic patients submitted to hippocampal and thalamic deep brain stimulation.

Science.gov (United States)

Cukiert, Arthur; Cukiert, Cristine Mella; Argentoni-Baldochi, Meire; Baise, Carla; Forster, Cássio Roberto; Mello, Valeria Antakli; Burattini, José Augusto; Lima, Alessandra Moura

2011-12-01

Deep brain stimulation (DBS) has been used in an increasing frequency for treatment of refractory epilepsy. Acute deep brain macrostimulation intraoperative findings were sparsely published in the literature. We report on our intraoperative macrostimulation findings during thalamic and hippocampal DBS implantation. Eighteen patients were studied. All patients underwent routine pre-operative evaluation that included clinical history, neurological examination, interictal and ictal EEG, high resolution 1.5T MRI and neuropsychological testing. Six patients with temporal lobe epilepsy were submitted to hippocampal DBS (Hip-DBS); 6 patients with focal epilepsy were submitted to anterior thalamic nucleus DBS (AN-DBS) and 6 patients with generalized epilepsy were submitted to centro-median thalamic nucleus DBS (CM-DBS). Age ranged from 9 to 40 years (11 males). All patients were submitted to bilateral quadripolar DBS electrode implantation in a single procedure, under general anesthesia, and intraoperative scalp EEG monitoring. Final electrode's position was checked postoperatively using volumetric CT scanning. Bipolar stimulation using the more proximal and distal electrodes was performed. Final standard stimulation parameters were 6Hz, 4V, 300μs (low frequency range: LF) or 130Hz, 4V, 300μs (high frequency range: HF). Bilateral recruiting response (RR) was obtained after unilateral stimulation in all patients submitted to AN and CM-DBS using LF stimulation. RR was widespread but prevailed over the fronto-temporal region bilaterally, and over the stimulated hemisphere. HF stimulation led to background slowing and a DC shift. The mean voltage for the appearance of RR was 4V (CM) and 3V (AN). CM and AN-DBS did not alter inter-ictal spiking frequency or morphology. RR obtained after LF Hip-DBS was restricted to the stimulated temporal lobe and no contralateral activation was noted. HF stimulation yielded no visually recognizable EEG modification. Mean intensity for initial

Early Nonresponse in the Antipsychotic Treatment of Acute Mania : A Criterion for Reconsidering Treatment? Results From an Individual Patient Data Meta-Analysis

NARCIS (Netherlands)

Welten, Carlijn C M; Koeter, Maarten W J; Wohlfarth, Tamar D; Storosum, Jitschak G; van den Brink, Wim; Gispen-de Wied, Christine C; Leufkens, Hubert G M; Denys, Damiaan A J P

OBJECTIVE: To investigate whether early nonresponse to antipsychotic treatment of acute mania predicts treatment failure and, if so, to establish the best definition or criterion of an early nonresponse. DATA SOURCES: Short-term efficacy studies assessing antipsychotics that were submitted to the

EVALUATION OF EARLY ISCHEMIC CHANGES IN STROKE PATIENTS TREATED WITH THROMBOLYTIC THERAPY

OpenAIRE

Kolevski Goran; Korneti-Pekevska Kostandina

2016-01-01

Introduction:The aim of this study is to evaluate early brain ischemic changes on CT scan in stroke patients in correlation with the clinical outcome, as well as to evaluate if there is prognostic and predictive features that can be used. Patients and methods: We examined 20 patients with acute ischemic stroke, from which 12 were male and 8 were female, at the age from 47 to 76 years. Results: The hyperdense medial artery (HMA) sign was present in 10 (50%) patients. Concerning the ASPECTS s...

[Meiotic abnormalities of oocytes from patients with endometriosis submitted to ovarian stimulation].

Science.gov (United States)

Barcelos, Ionara Diniz Evangelista Santos; Vieira, Rodolpho Cruz; Ferreira, Elisa Melo; Araújo, Maria Cristina Picinato Medeiros de; Martins, Wellington de Paula; Ferriani, Rui Alberto; Navarro, Paula Andrea de Albuquerque Salles

2008-08-01

to evaluate the meiotic spindle and the chromosome distribution of in vitro mature oocytes from stimulated cycles of infertile women with endometriosis, and with male and/or tubal infertility factors (Control Group), comparing the rates of in vitro maturation (IVM) between the two groups evaluated. fourteen patients with endometriosis and eight with male and/or tubal infertility factors, submitted to ovarian stimulation for intracytoplasmatic sperm injection have been prospectively and consecutively selected, and formed a Study and Control Group, respectively. Immature oocytes (46 and 22, respectively, from the Endometriosis and Control Groups) were submitted to IVM. Oocytes presenting extrusion of the first polar corpuscle were fixed and stained for microtubules and chromatin evaluation through immunofluorescence technique. Statistical analysis has been done by the Fisher's exact test, with statistical significance at pControl Groups, respectively). The chromosome and meiotic spindle organization was observed in 18 and 11 oocytes from the Endometriosis and Control Groups, respectively. In the Endometriosis Group, eight oocytes (44.4%) presented themselves as normal metaphase II (MII), three (16.7%) as abnormal MII, five (27.8%) were in telophase stage I and two (11.1%) underwent parthenogenetic activation. In the Control Group, five oocytes (45.4%) presented themselves as normal MII, three (27.3%) as abnormal MII, one (9.1%) was in telophase stage I and two (18.2%) underwent parthenogenetic activation. There was no significant difference in meiotic anomaly rate between the oocytes in MII from both groups. the present study data did not show significant differences in the IVM or in the meiotic anomalies rate between the IVM oocytes from stimulated cycles of patients with endometriosis, as compared with controls. Nevertheless, they have suggested a delay in the outcome of oocyte meiosis I from patients with endometriosis, shown by the higher proportion of oocytes in

20 CFR 10.801 - How are medical bills to be submitted?

Science.gov (United States)

2010-04-01

... employees, except for treatment and supplies provided by nursing homes, shall be supported by medical... separate bill shall be submitted when the employee is discharged from treatment or monthly, if treatment for the work-related condition is necessary for more than 30 days. (1)(i) Hospitals shall submit...

40 CFR 152.93 - Citation of a previously submitted valid study.

Science.gov (United States)

2010-07-01

... Data Submitters' Rights § 152.93 Citation of a previously submitted valid study. An applicant may demonstrate compliance for a data requirement by citing a valid study previously submitted to the Agency. The... the original data submitter, the applicant may cite the study only in accordance with paragraphs (b...

30 CFR 210.104 - Must I submit these production reports electronically?

Science.gov (United States)

2010-07-01

... MINERALS REVENUE MANAGEMENT FORMS AND REPORTS Production Reports-Oil and Gas § 210.104 Must I submit these... Production Reporter Handbook for the most current reporting options, instructions, and security measures. The... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Must I submit these production reports...

27 CFR 73.31 - May I submit forms electronically to TTB?

Science.gov (United States)

2010-04-01

... TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) PROCEDURES AND PRACTICES ELECTRONIC SIGNATURES; ELECTRONIC SUBMISSION OF FORMS Electronic Filing of Documents with TTB § 73.31 May I submit forms electronically to TTB? Yes; you may submit an electronic form, instead of a paper form, to satisfy any reporting...

An Evaluation of the Research Evidence on the Early Start Denver Model

Science.gov (United States)

Baril, Erika M.; Humphreys, Betsy P.

2017-01-01

The Early Start Denver Model (ESDM) has been gaining popularity as a comprehensive treatment model for children ages 12 to 60 months with autism spectrum disorders (ASD). This article evaluates the research on the ESDM through an analysis of study design and purpose; child participants; setting, intervention agents, and context; density and…

Methods for evaluating a mature substance abuse prevention/early intervention program.

Science.gov (United States)

Becker, L R; Hall, M; Fisher, D A; Miller, T R

2000-05-01

The authors describe methods for work in progress to evaluate four workplace prevention and/or early intervention programs designed to change occupational norms and reduce substance abuse at a major U.S. transportation company. The four programs are an employee assistance program, random drug testing, managed behavioral health care, and a peer-led intervention program. An elaborate mixed-methods evaluation combines data collection and analysis techniques from several traditions. A process-improvement evaluation focuses on the peer-led component to describe its evolution, document the implementation process for those interested in replicating it, and provide information for program improvement. An outcome-assessment evaluation examines impacts of the four programs on job performance measures (e.g., absenteeism, turnover, injury, and disability rates) and includes a cost-offset and employer cost-savings analysis. Issues related to using archival data, combining qualitative and quantitative designs, and working in a corporate environment are discussed.

Degradation study of Durolon polycarbonate submitted to gamma radiation

International Nuclear Information System (INIS)

Miranda, A.; Sciani, V.

1992-01-01

The effect of gamma radiation from a cobalt 60 source in the 27000 Durolon polycarbonate irradiated with doses between 0,2 and 1000 kGy at 25 0 C was analyzed. For this reason the samples was submitted to the mechanical assay of tension, deformation and hardness and optical assay of transmittance. The obtained results show a good mechanical stability of the polycarbonate, when it was submitted to gamma irradiation in doses up to 20 kGy. (C.G.C.). 05 refs., 04 figs

31 CFR 103.81 - Submitting requests.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Submitting requests. 103.81 Section 103.81 Money and Finance: Treasury Regulations Relating to Money and Finance FINANCIAL RECORDKEEPING... which the request is made. (b) A request filed by a corporation shall be signed by a corporate officer...

Applying the PCXMC software for dose assessment in patients submitted to abdomen and pelvis X-ray examinations

International Nuclear Information System (INIS)

Oliveira, V.L.S.; Silva, T.A. da

2009-01-01

The PCXMC R computational methodology was applied as a evaluation tool of the organ doses in patients submitted to different X-ray conventional diagnoses examinations. Simulations were made based in x-ray parameters and exposure geometry of three patient of same age group in an Emergency Hospital of the metropolitan area of Belo Horizonte city. Contributions to the effective dose from critical organs were evaluated and analyzed in terms of patient height and weight for the examinations of abdomen and pelvis. (author)

Genetic evaluation for TOR1-A (DYT1 in Brazilian patients with dystonia

Directory of Open Access Journals (Sweden)

Carlos Henrique F. Camargo

2014-10-01

Full Text Available Several genes have been mapped in families or in sporadic cases of dystonia. TOR1-A (DYT1 gene was linked to isolated dystonia. Objective To associate clinical information of patients with dystonia with the TOR1-A gene mutations. Method Eighty-eight patients with dystonia in cervical area (focal, segmental, multifocal and generalized were recruited at Movement Disorders Clinic of Hospital de Clínicas of the Federal University of Paraná between June of 2008 and June of 2009. They were submitted to the clinical evaluation. DNA was extract from blood and submitted at analysis to TOR1-A mutations by PCR according standard protocols. Results Two patients had c.907GAGdel mutation on TOR1-A gene. These patients, with familial history of dystonia, started his symptoms by legs and had secondary generalization. Conclusion We can suggest that analysis for TOR1-A mutations should be performed only in patients with early onset, generalized and familial dystonia.

Evaluation of capillary pore size characteristics in high-strength concrete at early ages

International Nuclear Information System (INIS)

Igarashi, Shin-ichi; Watanabe, Akio; Kawamura, Mitsunori

2005-01-01

The quantitative scanning electron microscope-backscattered electron (SEM-BSE) image analysis was used to evaluate capillary porosity and pore size distributions in high-strength concretes at early ages. The Powers model for the hydration of cement was applied to the interpretation of the results of image analysis. The image analysis revealed that pore size distributions in concretes with an extremely low water/binder ratio of 0.25 at early ages were discontinuous in the range of finer capillary pores. However, silica-fume-containing concretes with a water/binder ratio of 0.25 had larger amounts of fine pores than did concretes without silica fume. The presence of larger amounts of fine capillary pores in the concretes with silica fume may be responsible for greater autogenous shrinkage in the silica-fume-containing concretes at early ages

Evaluation of regulatory processes affecting nuclear power plant early site approval and standardization

International Nuclear Information System (INIS)

1983-12-01

This report presents the results of a survey and evaluation of existing federal, state and local regulatory considerations affecting siting approval of power plants in the United States. Those factors that may impede early site approval of nuclear power plants are identified, and findings related to the removal of these impediments and the general improvement of the approval process are presented. A brief evaluation of standardization of nuclear plant design is also presented

40 CFR 63.8818 - What reports must I submit and when?

Science.gov (United States)

2010-07-01

... other daily calibration checks. (f) The compliance report for a new or reconstructed flame lamination... not included in the list submitted with the Notification of Compliance Status in § 63.8816(h) (1), an... approved a different schedule for submission of reports under § 63.10(a), you must submit each compliance...

Color and opacity of composites protected with surface sealants and submitted to artificial accelerated aging.

Science.gov (United States)

Aguilar, Fabiano Gamero; Roberti Garcia, Lucas da Fonseca; Cruvinel, Diogo Rodrigues; Sousa, Ana Beatriz Silva; de Carvalho Panzeri Pires-de-Souza, Fernanda

2012-01-01

To evaluate the color similarity, stability and opacity of composites (TPH, Charisma, and Concept, shade A2) protected with surface sealants (Fortify Plus and Biscover) and cyanoacrylate (Super Bonder). Forty specimens of each composite were made and separated into 4 groups (n=10) according to the surface protection: GI - without sealant; GII - cyanoacrylate; GIII - Fortify Plus; GIV - Biscover. Color and opacity readings were taken before and after Artificial Acelerated Aging (AAA) and the values obtained for color stability were submitted to statistical analysis by 2-way ANOVA and Bonferroni's test (P<.05). The values acquired for color similarity were submitted to 1-way ANOVA and Tukey's test (P<.05). The specimen sufaces were compared before and after AAA using Scanning Electronic Microscopy (SEM). Studied composites did not present the same values for the coordinates L*, a* and b * before AAA, indicating that there was no color similarity among them. All composites presented color alteration after AAA with clinically unacceptable values. Protected groups presented lower opacity variation after AAA, in comparison with the control goup. SEM evaluation demonstrated that AAA increased the surface irregularities in all of the studied groups. Surface sealants were not effective in maintaining composite color, but were able to maintain opacity.

Early Prediction and Evaluation of Breast Cancer Response to Neoadjuvant Chemotherapy Using Quantitative DCE-MRI

Directory of Open Access Journals (Sweden)

Alina Tudorica

2016-02-01

Full Text Available The purpose is to compare quantitative dynamic contrast-enhanced (DCE magnetic resonance imaging (MRI metrics with imaging tumor size for early prediction of breast cancer response to neoadjuvant chemotherapy (NACT and evaluation of residual cancer burden (RCB. Twenty-eight patients with 29 primary breast tumors underwent DCE-MRI exams before, after one cycle of, at midpoint of, and after NACT. MRI tumor size in the longest diameter (LD was measured according to the RECIST (Response Evaluation Criteria In Solid Tumors guidelines. Pharmacokinetic analyses of DCE-MRI data were performed with the standard Tofts and Shutter-Speed models (TM and SSM. After one NACT cycle the percent changes of DCE-MRI parameters Ktrans (contrast agent plasma/interstitium transfer rate constant, ve (extravascular and extracellular volume fraction, kep (intravasation rate constant, and SSM-unique τi (mean intracellular water lifetime are good to excellent early predictors of pathologic complete response (pCR vs. non-pCR, with univariate logistic regression C statistics value in the range of 0.804 to 0.967. ve values after one cycle and at NACT midpoint are also good predictors of response, with C ranging 0.845 to 0.897. However, RECIST LD changes are poor predictors with C = 0.609 and 0.673, respectively. Post-NACT Ktrans, τi, and RECIST LD show statistically significant (P < .05 correlations with RCB. The performances of TM and SSM analyses for early prediction of response and RCB evaluation are comparable. In conclusion, quantitative DCE-MRI parameters are superior to imaging tumor size for early prediction of therapy response. Both TM and SSM analyses are effective for therapy response evaluation. However, the τi parameter derived only with SSM analysis allows the unique opportunity to potentially quantify therapy-induced changes in tumor energetic metabolism.

Preliminary early evaluation of radiation acute syndrome severity in an animal model

International Nuclear Information System (INIS)

Gimenez, J.C.; Nasazzi, N.B.; Taja, M.R.; Nagle, C.; Dubner, D.; Di Rizzio, C.

1992-01-01

To improve the knowledge of Radiation Acute Syndrome radiopathological picture, whole body x-rays irradiation at 2Gy of a primate (Cebus apella paraguayanus) used as model has been performed. Early evaluations of clinical symptoms and dose and damage biological indicators have shown that this primate has given out similar responses to those of man. (author)

Preliminary early evaluation of radiation acute syndrome severity in an animal model

Energy Technology Data Exchange (ETDEWEB)

Gimenez, J.C.; Nasazzi, N.B.; Taja, M.R. [Comision Nacional de Energia Atomica, (Argentina); Nagle, C. [Centro de Educacion Medica e Investigaciones Clinicas (Argentina); Dubner, D. [Comision Nacional de Energia Atomica, (Argentina); Di Rizzio, C. [Academia Nacional de Medicina (Argentina)

1992-07-01

To improve the knowledge of Radiation Acute Syndrome radiopathological picture, whole body x-rays irradiation at 2Gy of a primate (Cebus apella paraguayanus) used as model has been performed. Early evaluations of clinical symptoms and dose and damage biological indicators have shown that this primate has given out similar responses to those of man. (author)

Framework for evaluating public health surveillance systems for early detection of outbreaks: recommendations from the CDC Working Group.

Science.gov (United States)

Buehler, James W; Hopkins, Richard S; Overhage, J Marc; Sosin, Daniel M; Tong, Van

2004-05-07

The threat of terrorism and high-profile disease outbreaks has drawn attention to public health surveillance systems for early detection of outbreaks. State and local health departments are enhancing existing surveillance systems and developing new systems to better detect outbreaks through public health surveillance. However, information is limited about the usefulness of surveillance systems for outbreak detection or the best ways to support this function. This report supplements previous guidelines for evaluating public health surveillance systems. Use of this framework is intended to improve decision-making regarding the implementation of surveillance for outbreak detection. Use of a standardized evaluation methodology, including description of system design and operation, also will enhance the exchange of information regarding methods to improve early detection of outbreaks. The framework directs particular attention to the measurement of timeliness and validity for outbreak detection. The evaluation framework is designed to support assessment and description of all surveillance approaches to early detection, whether through traditional disease reporting, specialized analytic routines for aberration detection, or surveillance using early indicators of disease outbreaks, such as syndromic surveillance.

Inguinodynia in patients submitted to conventional inguinal hernioplasty.

Science.gov (United States)

Dias, Bruno Garcia; Santos, Marcelo Protásio Dos; Chaves, Ana Barbara DE Jesus; Willis, Mariana; Gomes, Marcio Couto; Andrade, Fernandes Tavares; Melo, Valdinaldo Aragão DE; Santos, Paulo Vicente Dos

2017-01-01

to evaluate the incidence of chronic pain and its impact on the quality of life of patients submitted to inguinal hernioplasty using the Lichtenstein technique. this was a descriptive, cross-sectional study of patients operated under spinal anesthesia from February 2013 to February 2015 and who had already completed six postoperative months. We questioned patients about the presence of chronic inguinal pain and, if confirmed, invited them to a consultation in which we assessed the pain and its impact on quality of life. out of 158 patients submitted to the procedure, we identified 7.6% as having inguinodynia. Of these, there was an impact on the quality of life in 25%. the incidence of inguinodynia after hernioplasty with repercussion in quality of life was similar to the one of found in the world literature. avaliar a incidência de dor crônica e o seu impacto na qualidade de vida de pacientes submetidos à hernioplastia inguinal pela técnica de Lichtenstein. trata-se de estudo transversal descritivo, de pacientes operados de hérnia inguinal pela técnica de Lichtenstein sob anestesia raquidiana, no período de fevereiro de 2013 a fevereiro de 2015, e que já haviam completado seis meses de pós-operatório. Os pacientes foram questionados sobre a presença de dor inguinal crônica e, caso confirmada, convidados a uma consulta na qual foi feita análise da qualidade da dor e seu impacto na qualidade de vida. do total de 158 pacientes submetidos ao procedimento, 7,6% foram identificados como portadores de inguinodinia. Destes, houve impacto na qualidade de vida em 25%. observou-se incidência de inguinodinia pós-hernioplastia com repercussão na qualidade de vida semelhante à literatura mundial.

Profile of patients submitted to gastroplasty in the university hospital of Maringá - Paraná State during 2008-2009 - doi: 10.4025/actascihealthsci.v35i2.12019

Directory of Open Access Journals (Sweden)

Kazuyuki Hashimoto

2013-06-01

Full Text Available This study evaluated the profile of patients submitted to gastroplasty in the University Hospital of Maringá during 2008-2009. Clinical charts were analyzed to obtain clinical and laboratory data of all patients with morbid obesity submitted to gastroplasty. During the study period, 28 surgeries were performed, 57% of the patients lived in Maringá, 82% female, 40 years average age, with mean body mass index (BMI of 46.7kg m-2. It was verified that 39% of the patients maintained an usual non-hypocaloric diet, 25% had quoted dietary reeducation, 36% were sedentary, and 29% practiced some physical activity, and remaining 1/3 of patients presented no data about lifestyle. Regarding associated pathologies, 79% were hypertensive, and 71% of patients presented fasting glucose above 100 mg dL-1, but only 12 of them had diagnosis of Type 2 diabetes mellitus. The hospital stay length was 4 days for 89% of the patients, and 11% had surgery complications. In this group of subjects, there was a clear preponderance of females and high prevalence of other pathologies. Identifying the profile of obese patients contributes to more effective decision-making and emphasizes the crucial role of multidisciplinary approach to health promotion and prevention of early and late complications of morbid obesity and gastroplasty.

75 FR 8364 - Proposed Data Collections Submitted for Public Comment and Recommendations

Science.gov (United States)

2010-02-24

... on proposed data collection projects, the Centers for Disease Control and Prevention (CDC) will... data base containing identifying death record information submitted annually to NCHS by all the State...] Proposed Data Collections Submitted for Public Comment and Recommendations In compliance with the...

30 CFR 254.7 - How do I submit my response plan to the MMS?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I submit my response plan to the MMS... do I submit my response plan to the MMS? You must submit the number of copies of your response plan that the appropriate MMS regional office requires. If you prefer to use improved information technology...

Microhardness and Roughness of Infiltrated White Spot Lesions Submitted to Different Challenges.

Science.gov (United States)

Neres, É Y; Moda, M D; Chiba, E K; Briso, Alf; Pessan, J P; Fagundes, T C

A white spot lesion is the first clinical sign of a caries lesion and represents mineral loss from the enamel subsurface. The purpose of this study was to evaluate the microhardness and surface roughness of white spot lesions after application of a resin infiltrant and subjection to different challenges. Caries-like lesions were induced in bovine enamel discs (n=50), and the specimens were randomly divided into five study groups (n=10): demineralized enamel (negative control, G1), infiltrated enamel (G2), infiltrated enamel submitted to brushing (G3), infiltrated enamel submitted to pH cycling (G4), and infiltrated enamel submitted to artificial aging (G5). Half of each enamel surface was used as its own positive control. Roughness data were analyzed using the Kruskal-Wallis test followed by the Dunn test. Results from microhardness were analyzed by two-way analysis of variance, followed by the Tukey test for multiple comparisons. The level of significance was set at 5%. Microhardness and roughness values obtained from the test side of the specimens were significantly lower compared with the sound enamel for all groups. Microhardness values obtained for G2, G3, and G5 were not significantly different. Values found for G1 were significantly lower compared with those for G2, G3, and G5. The lowest microhardness values were observed for G4, which was significantly different from the other groups. Surface roughness was not significantly different between G2 and G3. The resin infiltrant presented superiority over the unprotected white spot lesions, as they were more resistant to mechanical and aging challenges. However, resin infiltration was not able to reestablish the properties of sound enamel and was not resistant to a new cariogenic challenge.

21 CFR 720.7 - Notification of person submitting cosmetic product ingredient statement.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Notification of person submitting cosmetic product... AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY FILING OF COSMETIC PRODUCT INGREDIENT COMPOSITION STATEMENTS § 720.7 Notification of person submitting cosmetic product ingredient statement. When Form FDA...

Experiments on heat pipes submitted to strong accelerations; Experimentation de caloducs soumis a de fortes accelerations

Energy Technology Data Exchange (ETDEWEB)

Labuthe, A [Dassault Aviation, 92 - Saint Cloud (France)

1997-12-31

In order to evaluate the possibility to use heat pipes as efficient heat transfer devices in aircrafts, a study of their behaviour during strong accelerations is necessary. This study has been jointly carried out by the Laboratory of Thermal Studies of Poitiers (France) and Dassault Aviation company. It is based on a series of tests performed with an experimental apparatus that uses the centrifugal effect to simulate the acceleration fields submitted to the heat pipe. Un-priming - priming cycles have been performed under different power and acceleration levels and at various functioning temperatures in order to explore the behaviour of heat pipes: rate of un-priming and re-priming, functioning in blocked mode etc.. This preliminary study demonstrates the rapid re-priming of the tested heat pipes when submitted to favourable acceleration situations and the possibility to use them under thermosyphon conditions despite the brief unfavourable acceleration periods encountered. (J.S.)

Experiments on heat pipes submitted to strong accelerations; Experimentation de caloducs soumis a de fortes accelerations

Energy Technology Data Exchange (ETDEWEB)

Labuthe, A. [Dassault Aviation, 92 - Saint Cloud (France)

1996-12-31

In order to evaluate the possibility to use heat pipes as efficient heat transfer devices in aircrafts, a study of their behaviour during strong accelerations is necessary. This study has been jointly carried out by the Laboratory of Thermal Studies of Poitiers (France) and Dassault Aviation company. It is based on a series of tests performed with an experimental apparatus that uses the centrifugal effect to simulate the acceleration fields submitted to the heat pipe. Un-priming - priming cycles have been performed under different power and acceleration levels and at various functioning temperatures in order to explore the behaviour of heat pipes: rate of un-priming and re-priming, functioning in blocked mode etc.. This preliminary study demonstrates the rapid re-priming of the tested heat pipes when submitted to favourable acceleration situations and the possibility to use them under thermosyphon conditions despite the brief unfavourable acceleration periods encountered. (J.S.)

Early Primary Endoscopic Realignment of Posterior Urethral Injury- Evaluation and Follow-Up

Directory of Open Access Journals (Sweden)

Prasad Mylarappa

2013-07-01

Full Text Available Background: The management of complete orpartial posterior urethral disruption is contro-versial and much debate continues regarding theimmediate, early and delayed definitive therapy.Objective: We report our institutional experi-ence and long term result of early endoscopicrealignment of traumatic posterior urethral in-jury. Method and Materials: Between Septem-ber 1996 and March 2012, ninety six men witheither complete (84 or partial (12 posteriorurethral injury secondary to blunt trauma (11or pelvic fractures (85, presented to our insti-tution and these patients underwent immediatesuprapubic cystostomy followed by early pri-mary endoscopic realignment done 3-8 daysafter injury. Result: Seventy four patients(92.5% were continent after catheter removal.Urethral stricture was seen in seventy two pa-tients (90% of which fifty patients (69.4%had simple urethral stricture who were managedby urethral dilatation on outpatient basis. Four-teen patients (19.4% developed short stric-tures which were successfully treated with vi-sual internal urethrotomy. Eight patients(11.1% required anastomotic urethroplasty fordense stricture. Potency was retained in sev-enty five patients (93.75%. Urinary flow mea-surements at follow-up evaluation were satis-factory.Conclusion:Early primary endoscopic realign-ment in our experience reduces time to spon-taneous voiding, decrease the need for majorreconstructive surgery and long term supra pub-lic urinary diversion.

Alternative Student Growth Measures for Teacher Evaluation: Implementation Experiences of Early-Adopting Districts. REL 2015-093

Science.gov (United States)

McCullough, Moira; English, Brittany; Angus, Megan Hague; Gill, Brian

2015-01-01

Alternative student growth measures for teacher evaluation: Implementation experiences of early-adopting districts: State requirements to include student achievement growth in teacher evaluations are prompting the development of alternative ways to measure growth in grades and subjects not covered by state assessments. These alternative growth…

Oral-motor and electromyographic characterization of patients submitted to open a nd closed reductions of mandibular condyle fracture.

Science.gov (United States)

Silva, Amanda Pagliotto da; Sassi, Fernanda Chiarion; Andrade, Claudia Regina Furquim de

To characterize the oral-motor system of adults with mandibular condyle facture comparing the performance of individuals submitted to open reduction with internal fixation (ORIF) and closed reduction with mandibulomaxillary fixation (CRMMF). Study participants were 26 adults divided into three groups: G1 - eight individuals submitted to ORIF for correction of condyle fracture; G2 - nine individuals submitted to CRMMF for correction of condyle fracture; CG - nine healthy volunteers with no alterations of the orofacial myofunctional system. All participants underwent the same clinical protocol: assessment of the orofacial myofunctional system; evaluation of the mandibular range of motion; and surface electromyography (sEMG) of the masticatory muscles. Results indicated that patients with condyle fractures from both groups presented significant differences compared with those from the control group in terms of mobility of the oral-motor organs, mastication, and deglutition. Regarding the measures obtained for mandibular movements, participants with facial fractures from both groups showed significant differences compared with those from the control group, indicating greater restrictions in mandibular motion. As for the analysis of sEMG results, G1 patients presented more symmetrical masseter activation during the task of maximal voluntary teeth clenching. Patients with mandibular condyle fractures present significant deficits in posture, mobility, and function of the oral-motor system. The type of medical treatment does not influence the results of muscle function during the first six months after fracture reduction. Individuals submitted to ORIF of the condyle fracture present more symmetrical activation of the masseter muscle.

Early herding practices revealed through organic residue analysis of pottery from the early Neolithic rock shelter of Mala Triglavca, Slovenia

Directory of Open Access Journals (Sweden)

Lucija Šoberl

2008-12-01

Full Text Available A collection of pottery from the early Neolithic site of Mala Triglavca was analysed with the aim of obtaining insights into vessel use and early animal domestication and husbandry practices in the Adriatic region. Total lipid extracts were submitted to gas chromatography (GC, GC-mass spectrometry (GC-MS and GC-combustion-isotope ratio MS (GC-C-IRMS in order to obtain molecular and stable carbon isotope signatures as the basis for determining the nature and origins of the residues. The extracts were dominated by degraded animal fats. The majority (70% of the total lipid extracts displayed intact triacylglycerol distributions attributable to ruminant adipose and dairy fats, which were subsequently confirmed through C16:0 and C18:0 fatty acid δ13C values.

49 CFR Appendix II to Part 805 - Employees Required To Submit Statements

Science.gov (United States)

2010-10-01

...—Employees Required To Submit Statements Statements of employment and financial interests are required of the... 49 Transportation 7 2010-10-01 2010-10-01 false Employees Required To Submit Statements II...) Office of the managing director: (1) Legislative affairs officer. (2) Program analysis officer. (d...

A Preliminary Evaluation of Reach: Training Early Childhood Teachers to Support Children's Social and Emotional Development

Science.gov (United States)

Conners-Burrow, Nicola A.; Patrick, Terese; Kyzer, Angela; McKelvey, Lorraine

2017-01-01

This paper describes the development, implementation and preliminary evaluation of the Reaching Educators and Children (REACH) program, a training and coaching intervention designed to increase the capacity of early childhood teachers to support children's social and emotional development. We evaluated REACH with 139 teachers of toddler and…

Public health policy decisions on medical innovations: what role can early economic evaluation play?

Science.gov (United States)

Hartz, Susanne; John, Jürgen

2009-02-01

Our contribution aims to explore the different ways in which early economic data can inform public health policy decisions on new medical technologies. A literature research was conducted to detect methodological contributions covering the health policy perspective. Early economic data on new technologies can support public health policy decisions in several ways. Embedded in horizon scanning and HTA activities, it adds to monitoring and assessment of innovations. It can play a role in the control of technology diffusion by informing coverage and reimbursement decisions as well as the direct public promotion of healthcare technologies, leading to increased efficiency. Major problems include the uncertainty related to economic data at early stages as well as the timing of the evaluation of an innovation. Decision-makers can benefit from the information supplied by early economic data, but the actual use in practice is difficult to determine. Further empirical evidence should be gathered, while the use could be promoted by further standardization.

Is Something Better than Nothing? An Evaluation of Early Childhood Programs in Cambodia

Science.gov (United States)

Rao, Nirmala; Sun, Jin; Pearson, Veronica; Pearson, Emma; Liu, Hongyun; Constas, Mark A.; Engle, Patrice L.

2012-01-01

This study evaluated the relative effectiveness of home-based, community-based, and state-run early childhood programs across Cambodia. A total of 880 five-year-olds (55% girls) from 6 rural provinces in Cambodia attending State Preschools, Community Preschools, Home-Based Programs, or no programs were assessed twice using the Cambodian…

An Attempt of Early Detection of Poor Outcome after Whiplash

Science.gov (United States)

Laporte, Sebastien; Wang, Danping; Lecompte, Jennyfer; Blancho, Sophie; Sandoz, Baptiste; Feydy, Antoine; Lindberg, Pavel; Adrian, Julien; Chiarovano, Elodie; de Waele, Catherine; Vidal, Pierre-Paul

2016-01-01

The main concern with whiplash is that a large proportion of whiplash patients experience disabling symptoms or whiplash-associated disorders (WAD) for months if not years following the accident. Therefore, identifying early prognostic factors of WAD development is important as WAD have widespread clinical and economic consequences. In order to tackle that question, our study was specifically aimed at combining several methods of investigation in the same WAD patients at the acute stage and 6 months later. Our longitudinal, open, prospective, multi-center study included 38 whiplash patients, and 13 healthy volunteers matched for age, gender, and socio-economic status with the whiplash group. Whiplash patients were evaluated 15–21 days after road accident, and 6 months later. At each appointment, patients underwent a neuropsychological evaluation, a full clinical neurological examination, neurophysiological and postural tests, oto-neurological tests, cervical spine cord magnetic resonance imaging (MRI) with tractography (DTI). At 6 months, whiplash patients were categorized into two subgroups based on the results of the Diagnostic and Statistical Manual of Mental Disorders as having either favorable or unfavorable progression [an unfavorable classification corresponding to the presence of post-concussion symptom (PCS)] and we searched retrospectively for early prognostic factors of WAD predicting the passage to chronicity. We found that patients displaying high level of catastrophizing at the acute stage and/or post-traumatic stress disorder associated with either abnormalities in head or trunk kinematics, abnormal test of the otolithic function and at the Equitest or a combination of these syndromes, turned to chronicity. This study suggests that low-grade whiplash patients should be submitted as early as possible after the trauma to neuropsychological and motor control tests in a specialized consultation. In addition, they should be evaluated by a neuro

Influence of artificial accelerated aging on dimensional stability of acrylic resins submitted to different storage protocols.

Science.gov (United States)

Garcia, Lucas da Fonseca Roberti; Roselino, Lourenço de Moraes Rego; Mundim, Fabrício Mariano; Pires-de-Souza, Fernanda de Carvalho Panzeri; Consani, Simonides

2010-08-01

The aim of this study was to evaluate the influence of artificial accelerated aging on dimensional stability of two types of acrylic resins (thermally and chemically activated) submitted to different protocols of storage. One hundred specimens were made using a Teflon matrix (1.5 cm x 0.5 mm) with four imprint marks, following the lost-wax casting method. The specimens were divided into ten groups, according to the type of acrylic resin, aging procedure, and storage protocol (30 days). GI: acrylic resins thermally activated, aging, storage in artificial saliva for 16 hours, distilled water for 8 hours; GII: thermal, aging, artificial saliva for 16 hours, dry for 8 hours; GIII: thermal, no aging, artificial saliva for 16 hours, distilled water for 8 hours, GIV: thermal, no aging, artificial saliva for 16 hours, dry for 8 hours; GV: acrylic resins chemically activated, aging, artificial saliva for 16 hours, distilled water for 8 hours; GVI: chemical, aging, artificial saliva for 16 hours, dry for 8 hours; GVII: chemical, no aging, artificial saliva for 16 hours, distilled water for 8 hours; GVIII: chemical, no aging, artificial saliva for 16 hours, dry for 8 hours GIX: thermal, dry for 24 hours; and GX: chemical, dry for 24 hours. All specimens were photographed before and after treatment, and the images were evaluated by software (UTHSCSA - Image Tool) that made distance measurements between the marks in the specimens (mm), calculating the dimensional stability. Data were submitted to statistical analysis (two-way ANOVA, Tukey test, p= 0.05). Statistical analysis showed that the specimens submitted to storage in water presented the largest distance between both axes (major and minor), statistically different (p artificial accelerated aging and storage period influenced these alterations.

28 CFR 14.4 - Administrative claims; evidence and information to be submitted.

Science.gov (United States)

2010-07-01

... bearing on either the responsibility of the United States for the death or the damages claimed. (b... submitted. (a) Death. In support of a claim based on death, the claimant may be required to submit the following evidence or information: (1) An authenticated death certificate or other competent evidence...

20 CFR 669.510 - What planning documents must an NFJP grantee submit?

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What planning documents must an NFJP grantee submit? 669.510 Section 669.510 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... Accountability, Planning and Waiver Provision § 669.510 What planning documents must an NFJP grantee submit? Each...

What Good’s a Text? Textuality, Orality, and Mathematical Astronomy in Early Imperial China

OpenAIRE

Morgan, Daniel Patrick

2014-01-01

Article submitted to Archives internationales d'histoire des sciences; International audience; This paper examines a 226 ce debate on li 曆 mathematical astronomy at the Cao-Wei (226–265) court as a case study in the role of orality and person-to-person exchange in the transmission of astronomical knowledge in early imperial China. The li- and mathematics-related manuscripts to have come down to us from the early imperial period often suffer from textual corruption, the form that this corrupti...

40 CFR 60.2755 - When must I submit my waste management plan?

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... waste management plan? You must submit the waste management plan no later than the date specified in... Compliance Times for Commercial and Industrial Solid Waste Incineration Units that Commenced Construction On...

30 CFR 250.468 - What well records am I required to submit?

Science.gov (United States)

2010-07-01

... OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Drilling Operations...) You must submit copies of logs or charts of electrical, radioactive, sonic, and other well-logging... drilling operations in the GOM OCS Region, you must submit form MMS-133, Well Activity Report, to the...

45 CFR 35.4 - Administrative claims; evidence and information to be submitted.

Science.gov (United States)

2010-10-01

... bearing on either the responsibility of the United States for the death or the damages claimed. (b... information to be submitted. (a) Death. In support of a claim based on death, the claimant may be required to submit the following evidence or information: (1) An authenticated death certificate or other competent...

Color stability of maxillofacial silicone with nanoparticle pigment and opacifier submitted to disinfection and artificial aging.

Science.gov (United States)

Filié Haddad, Marcela; Coelho Goiato, Marcelo; Micheline Dos Santos, Daniela; Moreno, Amália; Filipe D'almeida, Nuno; Alves Pesqueira, Aldiéris

2011-09-01

The purpose of this study was to evaluate the color stability of a maxillofacial elastomer with the addition of a nanoparticle pigment and∕or an opacifier submitted to chemical disinfection and artificial aging. Specimens were divided into four groups (n = 30): group I: silicone without pigment or opacifier, group II: ceramic powder pigment, group III: Barium sulfate (BaSO(4)) opacifier, and group IV: ceramic powder and BaSO(4) opacifier. Specimens of each group (n = 10) were disinfected with effervescent tablets, neutral soap, or 4% chlorhexidine gluconate. Disinfection was done three times a week during two months. Afterward, specimens were submitted to different periods of artificial aging. Color evaluation was initially done, after 60 days (disinfection period) and after 252, 504, and 1008 h of artificial aging with aid of a reflection spectrophotometer. Data were analyzed by three-way ANOVA and Tukey test (α = 0.05). The isolated factor disinfection did not statistically influence the values of color stability among groups. The association between pigment and BaSO(4) opacifier (GIV) was more stable in relationship to color change (△E). All values of △E obtained, independent of the disinfectant and the period of artificial aging, were considered acceptable in agreement with the norms presented in literature.

Organising, Providing and Evaluating Technical Training for Early Career Researchers: A Case Study

Science.gov (United States)

van Besouw, Rachel M.; Rogers, Katrine S.; Powles, Christopher J.; Papadopoulos, Timos; Ku, Emery M.

2013-01-01

This paper considers the importance of providing technical training opportunities for Early Career Researchers (ECRs) worldwide through the case study of a MATLAB training programme, which was proposed, organised, managed and evaluated by a team of five ECRs at the University of Southampton. The effectiveness of the programme in terms of the…

12 CFR 793.4 - Administrative claims; evidence and information to be submitted.

Science.gov (United States)

2010-01-01

... evidence or information which may have a bearing on the responsibility of the United States for the death... GOVERNMENT Procedures § 793.4 Administrative claims; evidence and information to be submitted. (a) Death. In support of a claim based on death, the claimant may be required to submit the following evidence or...

Evaluation of buckling on containment metallic vessels

International Nuclear Information System (INIS)

Silveira, Renato Campos da; Mattar Neto, Miguel

2000-01-01

The buckling analysis represents one of the most important aspects of the structural projects of nuclear power plants containment metallic vessels and in this work the Case N-284-1 ASME Code is used for evaluation of those structures submitted to this failure mode. From the stress analysis, performed by using finite element method on discrete structures with shell elements, the procedure of the Code Case are applied to the evaluation of the containment metallic vessel of the Angra 2 nuclear power plant submitted to the own weight, seismic loads and uplift in case of accident. A study of pressure vessel reinforced by rings submit ed to the external pressure. Conclusions and commentaries are established based on the obtained results

18 CFR 154.302 - Previously submitted material.

Science.gov (United States)

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Previously submitted material. 154.302 Section 154.302 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... concurrently with the rate change filing. There must be furnished to the Director, Office of Energy Market...

Evaluation of the early enhancement of coronary atherosclerotic plaque by contrast-enhanced MR angiography

Energy Technology Data Exchange (ETDEWEB)

Li Tao [Department of Radiology, The General Hospital of Chinese People' s Armed Police Forces, Number 69, Yong Ding Road, Hai Dian District, Beijing (China); Department of Radiology, Chinese People' s Liberation Army General Hospital, Number 28, Fu Xing Road, Hai Dian District, Beijing (China); Zhao Xihai [Department of Radiology, Chinese People' s Liberation Army General Hospital, Number 28, Fu Xing Road, Hai Dian District, Beijing (China); Liu Xin [Paul C. Lauterbur Biomedical Imaging Center, Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Science, Shenzhen 518067 (China); Gao Jianhua [Department of Radiology, The General Hospital of Chinese People' s Armed Police Forces, Number 69, Yong Ding Road, Hai Dian District, Beijing (China); Zhao Shaohong [Department of Radiology, Chinese People' s Liberation Army General Hospital, Number 28, Fu Xing Road, Hai Dian District, Beijing (China); Li Xin; Zhou Weihua [Department of Radiology, The General Hospital of Chinese People' s Armed Police Forces, Number 69, Yong Ding Road, Hai Dian District, Beijing (China); Cai Zulong [Department of Radiology, Chinese People' s Liberation Army General Hospital, Number 28, Fu Xing Road, Hai Dian District, Beijing (China); Zhang Weiguo [Cardiovascular and Neurological Consulting Institute, 6771 San Fernando, Irving, TX 75039 (United States); Yang Li, E-mail: Yangli301@yahoo.com [Department of Radiology, Chinese People' s Liberation Army General Hospital, Number 28, Fu Xing Road, Hai Dian District, Beijing (China)

2011-10-15

Purpose: To evaluate the early enhancement of coronary atherosclerotic plaque using contrast-enhanced MR angiography (CE-MRA) and investigate the association between unstable angina pectoris (UAP) and early enhancement of the plaque. Methods: Forty-one patients presenting with angina pectoris and demonstrating single-vessel disease with non-calcified plaque and significant coronary stenosis ({>=}50%) on CTA were consecutively recruited for coronary CE-MRA. Contrast-to-noise ratio of the culprit plaque guided by CTA was measured on a cross-sectional multi-planar reconstruction image of the plaque on both pre- and post-CE-MRA. A 50% increasing of CNR was defined as plaque enhancement. The association between early enhancement of the plaques and UAP was analyzed. Results: Thirty-seven non-calcified plaques with significant coronary stenosis were detected in the 37 patients on MRA. 4 subjects were excluded because coronary atherosclerotic plaques were inadequate for identification on MRA. Of the 37 patients, 18 patients had UAP and other 19 patients presented stable angina pectoris (SAP). Of the 37 plaques on CE-MRA, 13 and 24 plaques presented early enhancement and no enhancement, respectively. Of the 13 early-enhanced plaques, 11 (85%) and 2 (15%) were found in the patients with UAP and SAP, respectively (p < 0.01). Of the 37 patients, 11 (61%) with UAP and 2 (11%) with SAP had early-enhanced plaques, respectively (p < 0.01). Conclusion: CE-MRA allows detection of early enhancement of coronary atherosclerotic plaque. The early enhancement is common in unstable angina and could be a sign of vulnerability.

Evaluating the Significance of Viscoelasticity in Diagnosing Early-Stage Liver Fibrosis with Transient Elastography.

Science.gov (United States)

Zhao, Jingxin; Zhai, Fei; Cheng, Jun; He, Qiong; Luo, Jianwen; Yang, Xueping; Shao, Jinhua; Xing, Huichun

2017-01-01

Transient elastography quantifies the propagation of a mechanically generated shear wave within a soft tissue, which can be used to characterize the elasticity and viscosity parameters of the tissue. The aim of our study was to combine numerical simulation and clinical assessment to define a viscoelastic index of liver tissue to improve the quality of early diagnosis of liver fibrosis. This is clinically relevant, as early fibrosis is reversible. We developed an idealized two-dimensional axisymmetric finite element model of the liver to evaluate the effects of different viscoelastic values on the propagation characteristics of the shear wave. The diagnostic value of the identified viscoelastic index was verified against the clinical data of 99 patients who had undergone biopsy and routine blood tests for staging of liver disease resulting from chronic hepatitis B infection. Liver stiffness measurement (LSM) and the shear wave attenuation fitting coefficient (AFC) were calculated from the ultrasound data obtained by performing transient elastography. Receiver operating curve analysis was used to evaluate the reliability and diagnostic accuracy of LSM and AFC. Compared to LSM, the AFC provided a higher diagnostic accuracy to differentiate early stages of liver fibrosis, namely F1 and F2 stages, with an overall specificity of 81.48%, sensitivity of 83.33% and diagnostic accuracy of 81.82%. AFC was influenced by the level of LSM, ALT. However, there are no correlation between AFC and Age, BMI, TBIL or DBIL. Quantification of the viscoelasticity of liver tissue provides reliable measurement to identify and differentiate early stages of liver fibrosis.

Evaluation of Oral Mucositis Occurrence in Oncologic Patients under Antineoplastic Therapy Submitted to the Low-Level Laser Coadjuvant Therapy.

Science.gov (United States)

Leite Cavalcanti, Alessandro; José de Macêdo, Dário; Suely Barros Dantas, Fernanda; Dos Santos Menezes, Karla; Filipe Bezerra Silva, Diego; Alves de Melo Junior, William; Fabia Cabral Cavalcanti, Alidianne

2018-04-24

Low-level laser therapy has been widely used in treating many conditions, including oral mucositis. The purpose of this study was to evaluate the occurrence of oral mucositis in patients undergoing antineoplastic therapy submitted to preventive and therapeutic treatment with low-level laser therapy. This cross-sectional study was carried out with 51 children and adolescents of both sexes with malignant neoplasias who developed oral mucositis and underwent low-level laser therapy. Data were collected on sex, age, type and degree of neoplasia, region affected, and remission time. 64.7% of the patients were male and were between 3 and 6 years of age (39.2%). Acute lymphoid leukemia was the most frequent neoplasm (37.3%). Regarding the maximum oral mucositis, grade 2 (41.2%) was predominant, with jugal mucosa (29.9%) and tongue (17.7%) being the most affected regions. The majority of cases presented lesion remission time between 4 and 7 days (44.0%). Most patients were young, male, and diagnosed with acute lymphoid leukemia. Predominance of grade 2 oral mucositis was observed, with jugal mucosa and tongue being the most affected regions, with the majority of cases presenting lesion remission time between 4 and 7 days. Low-level laser therapy has been shown to be an essential therapy in the prevention and treatment of these lesions, since it is a non-invasive and low-cost method.

75 FR 60404 - Information Collection Request Submitted to Office of Management and Budget

Science.gov (United States)

2010-09-30

... [OMB Control Number: 3002-0003] Information Collection Request Submitted to Office of Management and... United States will submit an Information Collection Request (ICR) to the Office of Management and Budget (OMB) requesting approval for the following collection of information: 3002-0003, Substitute...

76 FR 75894 - Information Collection Activities: Pipelines and Pipeline Rights-of-Way; Submitted for Office of...

Science.gov (United States)

2011-12-05

...) Submit repair report 3 1008(f) Submit report of pipeline failure analysis...... 30 1008(g) Submit plan of... usual and customary business practice; required burden is minimal to make available to BSEE. Estimated... and provide your total capital and startup cost components or annual operation, maintenance, and...

24 CFR 3282.354 - Submittal of false information or refusal to submit information.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Submittal of false information or... ENFORCEMENT REGULATIONS Primary Inspection Agencies § 3282.354 Submittal of false information or refusal to submit information. The submittal of false information or the refusal to submit information required...

27 CFR 73.34 - When is an electronically submitted form considered timely filed?

Science.gov (United States)

2010-04-01

... AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) PROCEDURES AND PRACTICES ELECTRONIC SIGNATURES; ELECTRONIC SUBMISSION OF FORMS Electronic Filing of Documents with TTB § 73.34 When is an electronically submitted form considered timely filed? If you submit a form to our electronic...

34 CFR 97.123 - Early termination of research support: Evaluation of applications and proposals.

Science.gov (United States)

2010-07-01

... PROTECTION OF HUMAN SUBJECTS Federal Policy for the Protection of Human Subjects (Basic ED Policy for Protection of Human Research Subjects) § 97.123 Early termination of research support: Evaluation of... the protection of the rights and welfare of human subjects (whether or not the research was subject to...

Simplified Analytical Methods to Analyze Lock Gates Submitted to Ship Collisions and Earthquakes

Directory of Open Access Journals (Sweden)

Buldgen Loic

2015-09-01

Full Text Available This paper presents two simplified analytical methods to analyze lock gates submitted to two different accidental loads. The case of an impact involving a vessel is first investigated. In this situation, the resistance of the struck gate is evaluated by assuming a local and a global deforming mode. The super-element method is used in the first case, while an equivalent beam model is simultaneously introduced to capture the overall bending motion of the structure. The second accidental load considered in this paper is the seismic action, for which an analytical method is presented to evaluate the total hydrodynamic pressure applied on a lock gate during an earthquake, due account being taken of the fluid-structure interaction. For each of these two actions, numerical validations are presented and the analytical results are compared to finite-element solutions.

[Analysis of the otorhinolaryngological doctoral theses submitted in Spain between 1976 and 2005].

Science.gov (United States)

de Diego, Juan Ignacio; Prim, María Pilar

2008-01-01

The importance of otorhinolaryngology as a separate branch of medicine has grown in the last decades. The objective of this work is to analyze the doctoral theses in ENT presented in Spain between 1976 and 2005. The TESEO database was searched for theses on otorhinolaryngology produced in Spain between 1976 and 2005. The search criteria used were the terms "Otorhinolaryngology," "Ear, nose, and throat surgery," "Hearing physiology," "Vestibular physiology," "Hearing physics," and "Bioacoustics". 468 theses were found (15.6 theses/year). Of these, 343 (73.6 %) were submitted by otorhinolaryngologists. The Universities of Valencia (Estudi General) (49), Complutense of Madrid (42), Salamanca (39), Barcelona (35), and Autònoma of Barcelona (31) accounted for most of the theses. The name of the supervisor was listed in 376 of the 468 theses (80.4 %); 286 of them had only 1 supervisor (76.1 %) and 90 had 2 (23.9 %). The most frequent topics were otology and audiology (35.1 %). Otorhinolaryngology in Spain has produced a similar number of theses as other areas of knowledge evaluated. The supervision of theses has tended to be shared in the most recent years studied. The number of theses submitted each year did not have only academic influences but also non-academic reasons.

7 CFR 28.954 - Costs of submitting samples.

Science.gov (United States)

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Costs of submitting samples. 28.954 Section 28.954 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER...

Web Based Application for Early Detection of Vitamin and Mineral Deficiency

Directory of Open Access Journals (Sweden)

Nina Sevani

2016-10-01

Full Text Available Deficiency of vitamin and mineral as part of micronutrient deficiency may lower human productivity. In general, lack of public understanding about micronutrient, limited number of nutritionist, time and cost, became the reason for people reluctant to meet nutritionist. The use of web-based computer application can be implemented to overcome the difficulty to get nutritionist’s services. Using the application, user can detect and check their micronutrient condition independently. User can submit their physical condition by answering questions from the application. Using forward chaining inference, data from user will be proceed using certainty factor method. The application’s output are the possible type of micronutrient’s deficiency and the weight that shown the level of confidence of the result. The evaluation process shown that the application functioning properly in line with the expectation. Beside helping people to make early detection independenly, the presence of the application is also expected to increase public awareness about the importance of micronutrient in their life.   

Evaluation of selected maps used in early school education in Poland and proposal of a new solution

Directory of Open Access Journals (Sweden)

Słomska Katarzyna

2017-07-01

Full Text Available The author presents criteria of evaluation and assumption for early school education maps. Attention was payed to needs and perceptual possibilities of map users and cartographic correctness of maps. Main criteria of map evaluation – content and form of a map – have their unique attributes. In case of the first criterion they are accuracy and currency, classification of content and usability. Second criterion consist of: composition, colours, labels on the map and readability. Materials commissioned by Ministry of National Education were evaluated on the said criteria basis. Evaluation of maps for early school education revealed their flaws, among which absence of a scale can be named. Afterwards assumptions were developed and used to prepare own proposal of a map. Achieving maximum readability was a priority. Other assumptions concerned graphic balance, classification and hierarchy of content, simplicity of elaboration, usage of readable typefaces and adjustment of transmission to the age of users.

Early hospital discharge and early puerperal complications.

Science.gov (United States)

Ramírez-Villalobos, Dolores; Hernández-Garduño, Adolfo; Salinas, Aarón; González, Dolores; Walker, Dilys; Rojo-Herrera, Guadalupe; Hernández-Prado, Bernardo

2009-01-01

To evaluate the association between time of postpartum discharge and symptoms indicative of complications during the first postpartum week. Women with vaginal delivery at a Mexico City public hospital, without complications before the hospital discharge, were interviewed seven days after delivery. Time of postpartum discharge was classified as early (25 hours). The dependent variable was defined as the occurrence and severity of puerperal complication symptoms. Out of 303 women, 208 (68%) were discharged early. However, women with early discharge and satisfactory prenatal care had lower odds of presenting symptoms in early puerperium than women without early discharge and inadequate prenatal care (OR 0.36; 95% confidence intervals = 0.17-0.76). There was no association between early discharge and symptoms of complications during the first postpartum week; the odds of complications were lower for mothers with early discharge and satisfactory prenatal care.

Development, evaluation, and utility of a peer evaluation form for online teaching.

Science.gov (United States)

Gaskamp, Carol D; Kintner, Eileen

2014-01-01

Formative assessment of teaching by peers is an important component of quality improvement for educators. Teaching portfolios submitted for promotion and tenure are expected to include peer evaluations. Faculty resources designed for peer evaluation of classroom teaching are often inadequate for evaluating online teaching. The authors describe development, evaluation, and utility of a new peer evaluation form for formative assessment of online teaching deemed relevant, sound, feasible, and beneficial.

[Evaluation and analysis of monitoring and early warning functions of the occupational disease reporting system in China].

Science.gov (United States)

Zhu, Xiaojun; Li, Tao; Liu, Mengxuan

2015-06-01

To evaluate the monitoring and early warning functions of the occupational disease reporting system right now in China, and to analyze their influencing factors. An improved audit tool (ODIT) was used to score the monitoring and early warning functions with a total score of 10. The nine indices were completeness of information on the reporting form, coverage of the reporting system, accessibility of criteria or guidelines for diagnosis, education and training for physicians, completeness of the reporting system, statistical methods, investigation of special cases, release of monitoring information, and release of early warning information. According to the evaluation, the occupational disease reporting system in China had a score of 5.5 in monitoring existing occupational diseases with a low score for release of monitoring information; the reporting system had a score of 6.5 in early warning of newly occurring occupational diseases with low scores for education and training for physicians as well as completeness of the reporting system. The occupational disease reporting system in China still does not have full function in monitoring and early warning. It is the education and participation of physicians from general hospitals in the diagnosis and treatment of occupational diseases and suspected occupational diseases that need to be enhanced. In addition, the problem of monitoring the incidence of occupational diseases needs to be solved as soon as possible.

Nutritional assessment methods as predictors of postoperative mortality in gastric cancer patients submitted to gastrectomy

Directory of Open Access Journals (Sweden)

Aline Kirjner Poziomyck

Full Text Available ABSTRACT Objectives: to determine the nutritional evaluation method that best predicts mortality in 90 days of patients submitted to gastrectomy for gastric cancer. Methods: we conducted a prospective study with 44 patients with gastric cancer, stages II to IIIa, of whom nine were submitted to partial gastrectomy, 34 to total gastrectomy, and one to esophago-gastrectomy. All patients were nutritionally evaluated through the same protocol, up to 72h after hospital admission. The parameters used were Patient-Generated Subjective Global Assessment (PGSGA, classical anthropometry, current weight and height, percentage of weight loss (%WL and body mass index (BMI. We also measured the thickness of the thumb adductor muscle (TAM in both hands, dominant hand (TAMD and non-dominant hand (TAMND, as well as the calculated the prognostic nutritional index (PNI. The laboratory profile included serum levels of albumin, erythrocytes, hemoglobin, hematocrit, leukocytes, and total lymphocytes count (TLC. Results: of the 44 patients studied, 29 (66% were malnourished by the subjective method, 15 being grade A, 18 grade B and 11 grade C. Cases with PGSGA grade B and TAMD 10.2±2.9 mm were significantly associated with higher mortality. The ROC curves (95% confidence interval of both PGSGA and TAMD thickness reliably predicted mortality at 30 and 90 days. No laboratory method allowed predicting mortality at 90 days. Conclusion: PGSGA and the TAMD thickness can be used as preoperative parameters for risk of death in patients undergoing gastrectomy for gastric cancer.

Colour stability of temporary restorations with different thicknesses submitted to artificial accelerated aging.

Science.gov (United States)

Silame, F D J; Tonani, R; Alandia-Roman, C C; Chinelatti, M; Panzeri, H; Pires-de-Souza, F C P

2013-12-01

This study evaluated the colour stability of temporary prosthetic restorations with different thicknesses submitted to artificial accelerated aging. The occlusal surfaces of 40 molars were grinded to obtain flat enamel surfaces. Twenty acrylic resin specimens [Polymethyl methacrylate (Duralay) and Bis-methyl acrylate (Luxatemp)] were made with two different thicknesses, 0.5 mm and 1.0 mm. Temporary restorations were fixed on enamel and CIE L*a*b* colour parameters of each specimen were assessed before and after artificial accelerated aging. All groups showed colour alterations above the clinically acceptable limit. Luxatemp showed the lowest colour alteration regardless its thickness and Duralay showed the greatest alteration with 0.5 mm.

Presentations and documents submitted to the 26. meeting, NEA Headquarters

International Nuclear Information System (INIS)

2014-05-01

The NEA's nuclear data evaluation co-operation activities involve the following evaluation projects: ENDF (United States), JENDL (Japan), ROSFOND/BROND (Russia), JEFF (other Data Bank member countries) and CENDL (China) in close co-operation with the Nuclear Data Section of the International Atomic Energy Agency (IAEA). The working party was established to promote the exchange of information on nuclear data evaluations, measurements, nuclear model calculations, validation, and related topics, and to provide a framework for co-operative activities between the participating projects. The working party assesses nuclear data improvement needs and addresses these needs by initiating joint evaluation and/or measurement efforts. This document is a compilation of the available Presentations (slides) and documents (reports) submitted to the 26. WPEC meeting: Summary record of the previous meeting, May 2013; Membership and observers - May 2014 (Participation, Informal discussions on criteria defining an 'evaluation project'); 25. Anniversary of WPEC and brief overview of WPEC history; Reports on experimental activities: Europe, Japan, USA, Russia (no presentation available), China; Brief progress reports from the evaluation projects: ENDF, JEFF, JENDL, BROND/ROSFOND (no presentation available), CENDL, IAEA, TENDL; Status of subgroups: Subgroup 27: Prompt photon production from fission products (no presentation available), Subgroup 28: Processing of covariance data, Subgroup 31: Meeting nuclear data needs for advanced reactors, Subgroup 33: Methods and issues for the combined use of integral experiments and covariance data, Subgroup 34: Coordinated evaluation of Pu-239 in the resonance region, Subgroup 35: Scattering angular distribution in the fast energy range (no presentation available), Subgroup 36: Reporting and usage of experimental data for evaluation in the resolved resonance region, Subgroup 37: Improved fission product yield evaluation methodologies, Subgroup 38: A

Investigating Key Psychometric Properties of the French Version of the Early Years Evaluation-Teacher Assessment

Science.gov (United States)

Laurie, Robert; Sloat, Elizabeth

2016-01-01

This research investigates key psychometric properties of the French Early Years Evaluation-Teacher Assessment measure designed to systematically assess kindergarten children across five social and academic developmental domains: awareness of self and environment, social skills and behaviour, cognitive abilities, language and communication, and…

Report of the evaluation by the Ad Hoc Review Committee on advance science research. Result evaluation, interim evaluation, in-advance evaluation in fiscal year 2003

International Nuclear Information System (INIS)

2003-11-01

The Research Evaluation Committee, which consisted of 13 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Advanced Science Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the accomplishments of the research completed in Fiscal Year 2002, the accomplishments of the research started in Fiscal Year 2001, and the adequacy of the programs of the research to be started in Fiscal Year 2004 at Advanced Science Research Center of JAERI. The Ad Hoc Review Committee consisted of nine specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from May to July 2003. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on June 24, 2003, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on August 4, 2003. This report describes the result of the evaluation by the Ad Hoc Review Committee on Advanced Science Research. (author)

Report of the evaluation by the Ad Hoc Review Committee on Advance Science Research. Result evaluation, interim evaluation, in-advance evaluation in fiscal year 2002

Energy Technology Data Exchange (ETDEWEB)

NONE

2002-11-01

The Research Evaluation Committee, which consisted of 13 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Advanced Science Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the accomplishments of the research completed in Fiscal Year 2001, the accomplishments of the research started in Fiscal Year 2000, and the adequacy of the programs of the research to be started in Fiscal Year 2003 at Advanced Science Research Center of JAERI. The Ad Hoc Review Committee consisted of eight specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from May to July 2002. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on June 4, 2002, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on August 5, 2002. This report describes the result of the evaluation by the Ad Hoc Review Committee on Advanced Science Research. (author)

Monitoring and Evaluation of an Early Childhood Development Programme: Implications for Leadership and Management

Science.gov (United States)

Hodgson, Sarah; Papatheodorou, Theodora; James, Mary

2014-01-01

The article aims to discuss preliminary findings from a participatory monitoring and evaluation (M&E) framework, used in a community-based early childhood development (ECD) programme in KwaZulu-Natal South Africa, and their implications for leadership and management. The purposes of the M&E were for LETCEE, the implementing organization,…

49 CFR 655.49 - Refusal to submit to a drug or alcohol test.

Science.gov (United States)

2010-10-01

... 49 Transportation 7 2010-10-01 2010-10-01 false Refusal to submit to a drug or alcohol test. 655... TRANSIT ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PREVENTION OF ALCOHOL MISUSE AND PROHIBITED DRUG USE IN TRANSIT OPERATIONS Types of Testing § 655.49 Refusal to submit to a drug or alcohol test. (a) Each...

Colour stability of denture teeth submitted to different cleaning protocols and accelerated artificial aging.

Science.gov (United States)

Freire, T S; Aguilar, F G; Garcia, L da Fonseca Roberti; Pires-de-Souza, F de Carvalho Panzeri

2014-03-01

Acrylic resin is widely used for artificial teeth manufacturing due to several important characteristics; however, this material do not present acceptable colour stability over the course of time. This study evaluated the effect of different cleaning protocols and accelerated artificial aging on colour stability of denture teeth made of acrylic resin. Sixty denture teeth in dark and light shades were used, and separated according to the treatment to which they were submitted. Results demonstrated that colour stability of artificial teeth is influenced by the cleaning solution and artificial aging, being dark teeth more susceptible to colour alteration than lighter ones.

Evaluation of early atherosclerotic findings in women with polycystic ovary syndrome

Directory of Open Access Journals (Sweden)

Mohammadi Afshin

2011-10-01

Full Text Available Background Polycystic ovary syndrome (PCOS is the most common endocrinopathy in women of childbearing age, and it seems better to consider it as an ovarian manifestation of metabolic syndrome. The aim of the current study was to evaluate early atherosclerotic findings in patients with PCOS. Methods We enrolled 46 women with PCOS and 45 normal control subjects who were referred to our hospital's endocrinology outpatient clinic. Carotid intima media thickness (CIMT and flow-mediated dilatation (FMD were performed in both cases and matched controls. Results Patients with PCOS showed an increased mean CIMT (0.63 ± 0.16 mm when compared with the control subjects (0.33 ± 0.06 mm. This difference was statistically significant (p = 0.001. The mean FMD in young patients with PCOS was 10.07 ± 1.2%, while it was 6.5 ± 2.06% in normal subjects. This difference was also statistically significant (p = 0.001. Conclusion Our findings suggest that PCOS is related with early atherosclerotic findings.

Evaluation of Oral Mucositis Occurrence in Oncologic Patients under Antineoplastic Therapy Submitted to the Low-Level Laser Coadjuvant Therapy

Directory of Open Access Journals (Sweden)

Alessandro Leite Cavalcanti

2018-04-01

Full Text Available Low-level laser therapy has been widely used in treating many conditions, including oral mucositis. The purpose of this study was to evaluate the occurrence of oral mucositis in patients undergoing antineoplastic therapy submitted to preventive and therapeutic treatment with low-level laser therapy. This cross-sectional study was carried out with 51 children and adolescents of both sexes with malignant neoplasias who developed oral mucositis and underwent low-level laser therapy. Data were collected on sex, age, type and degree of neoplasia, region affected, and remission time. 64.7% of the patients were male and were between 3 and 6 years of age (39.2%. Acute lymphoid leukemia was the most frequent neoplasm (37.3%. Regarding the maximum oral mucositis, grade 2 (41.2% was predominant, with jugal mucosa (29.9% and tongue (17.7% being the most affected regions. The majority of cases presented lesion remission time between 4 and 7 days (44.0%. Most patients were young, male, and diagnosed with acute lymphoid leukemia. Predominance of grade 2 oral mucositis was observed, with jugal mucosa and tongue being the most affected regions, with the majority of cases presenting lesion remission time between 4 and 7 days. Low-level laser therapy has been shown to be an essential therapy in the prevention and treatment of these lesions, since it is a non-invasive and low-cost method.

Evaluating surveillance strategies for the early detection of low pathogenicity avian influenza infections.

Science.gov (United States)

Comin, Arianna; Stegeman, Arjan; Marangon, Stefano; Klinkenberg, Don

2012-01-01

In recent years, the early detection of low pathogenicity avian influenza (LPAI) viruses in poultry has become increasingly important, given their potential to mutate into highly pathogenic viruses. However, evaluations of LPAI surveillance have mainly focused on prevalence and not on the ability to act as an early warning system. We used a simulation model based on data from Italian LPAI epidemics in turkeys to evaluate different surveillance strategies in terms of their performance as early warning systems. The strategies differed in terms of sample size, sampling frequency, diagnostic tests, and whether or not active surveillance (i.e., routine laboratory testing of farms) was performed, and were also tested under different epidemiological scenarios. We compared surveillance strategies by simulating within-farm outbreaks. The output measures were the proportion of infected farms that are detected and the farm reproduction number (R(h)). The first one provides an indication of the sensitivity of the surveillance system to detect within-farm infections, whereas R(h) reflects the effectiveness of outbreak detection (i.e., if detection occurs soon enough to bring an epidemic under control). Increasing the sampling frequency was the most effective means of improving the timeliness of detection (i.e., it occurs earlier), whereas increasing the sample size increased the likelihood of detection. Surveillance was only effective in preventing an epidemic if actions were taken within two days of sampling. The strategies were not affected by the quality of the diagnostic test, although performing both serological and virological assays increased the sensitivity of active surveillance. Early detection of LPAI outbreaks in turkeys can be achieved by increasing the sampling frequency for active surveillance, though very frequent sampling may not be sustainable in the long term. We suggest that, when no LPAI virus is circulating yet and there is a low risk of virus introduction

Evaluating surveillance strategies for the early detection of low pathogenicity avian influenza infections.

Directory of Open Access Journals (Sweden)

Arianna Comin

Full Text Available In recent years, the early detection of low pathogenicity avian influenza (LPAI viruses in poultry has become increasingly important, given their potential to mutate into highly pathogenic viruses. However, evaluations of LPAI surveillance have mainly focused on prevalence and not on the ability to act as an early warning system. We used a simulation model based on data from Italian LPAI epidemics in turkeys to evaluate different surveillance strategies in terms of their performance as early warning systems. The strategies differed in terms of sample size, sampling frequency, diagnostic tests, and whether or not active surveillance (i.e., routine laboratory testing of farms was performed, and were also tested under different epidemiological scenarios. We compared surveillance strategies by simulating within-farm outbreaks. The output measures were the proportion of infected farms that are detected and the farm reproduction number (R(h. The first one provides an indication of the sensitivity of the surveillance system to detect within-farm infections, whereas R(h reflects the effectiveness of outbreak detection (i.e., if detection occurs soon enough to bring an epidemic under control. Increasing the sampling frequency was the most effective means of improving the timeliness of detection (i.e., it occurs earlier, whereas increasing the sample size increased the likelihood of detection. Surveillance was only effective in preventing an epidemic if actions were taken within two days of sampling. The strategies were not affected by the quality of the diagnostic test, although performing both serological and virological assays increased the sensitivity of active surveillance. Early detection of LPAI outbreaks in turkeys can be achieved by increasing the sampling frequency for active surveillance, though very frequent sampling may not be sustainable in the long term. We suggest that, when no LPAI virus is circulating yet and there is a low risk of virus

Infection by Cryptosporidium parvum in renal patients submitted to renal transplant or hemodialysis

Directory of Open Access Journals (Sweden)

Chieffi Pedro Paulo

1998-01-01

Full Text Available The frequency of infection by Cryptosporidium parvum was determined in two groups of renal patients submitted to immunosuppression. One group consisted of 23 renal transplanted individuals, and the other consisted of 32 patients with chronic renal insufficiency, periodically submitted to hemodialysis. A third group of 27 patients with systemic arterial hypertension, not immunosuppressed, was used as control. During a period of 18 months all the patients were submitted to faecal examination to detect C. parvum oocysts, for a total of 1 to 6 tests per patient. The results showed frequencies of C. parvum infection of 34.8%, 25% and 17.4%, respectively, for the renal transplanted group, the patients submitted to hemodialysis and the control group. Statistical analysis showed no significant differences among the three groups even though the frequency of C. parvum infection was higher in the transplanted group. However, when the number of fecal samples containing C. parvum oocysts was taken in account, a significantly higher frequency was found in the renal transplanted group.

HRCT in the evaluation and diagnosis of the early/active pulmonary tuberculosis

International Nuclear Information System (INIS)

Tan Gao; Liu Xueguo; Zhang Qingwen; Wang Ying; Li Zhanjun; Zhang Cuiyun; Wang Jian; He Yanli; Hong Guobin

2003-01-01

Objective: To evaluate the HRCT findings of early/active pulmonary tuberculosis before and after antituberculous chemotherapy. Methods: One hundred tuberculous patients were studied prospectively and they were divided into 2 groups according to the history. The diagnosis of early active pulmonary tuberculosis was based on positive acid-fast bacilli in sputum (75 patients) and changes on serial radiographs obtained during treatment (25 patients). The correlation between pathology and imaging was done in the lungs from the cadavers of five other patients who died of pulmonary tuberculosis. Results: Comparing with the presence of other HRCT findings, the presence of centrilobular lesions (93.0%), tree-in-bud appearance (76.0%), and wall thickening of bronchioles (70.0%) were most common signs in both the first group consisting of 66 patients with newly diagnosed pulmonary tuberculosis and the second group consisting of 34 patients with recent reactivation of pulmonary tuberculosis at examination by HRCT, and there was significant difference between the presence of those signs and other signs (P<0.001). Conclusion: Centrilobular lesion appeared to be the most commonly seen characteristic HRCT features of early active tuberculosis, and it may be helpful to the diagnosis and (or ) differential diagnosis if combined with other commonly seen characteristic HRCT features as well as clinical information

Early warning systems and rapid response to the deteriorating patient in hospital: A realist evaluation.

Science.gov (United States)

McGaughey, Jennifer; O'Halloran, Peter; Porter, Sam; Trinder, John; Blackwood, Bronagh

2017-12-01

To test the Rapid Response Systems programme theory against actual practice components of the Rapid Response Systems implemented to identify those contexts and mechanisms which have an impact on the successful achievement of desired outcomes in practice. Rapid Response Systems allow deteriorating patients to be recognized using Early Warning Systems, referred early via escalation protocols and managed at the bedside by competent staff. Realist evaluation. The research design was an embedded multiple case study approach of four wards in two hospitals in Northern Ireland which followed the principles of Realist Evaluation. We used various mixed methods including individual and focus group interviews, observation of nursing practice between June-November 2010 and document analysis of Early Warning Systems audit data between May-October 2010 and hospital acute care training records over 4.5 years from 2003-2008. Data were analysed using NiVivo8 and SPPS. A cross-case analysis highlighted similar patterns of factors which enabled or constrained successful recognition, referral and response to deteriorating patients in practice. Key enabling factors were the use of clinical judgement by experienced nurses and the empowerment of nurses as a result of organizational change associated with implementation of Early Warning System protocols. Key constraining factors were low staffing and inappropriate skill mix levels, rigid implementation of protocols and culturally embedded suboptimal communication processes. Successful implementation of Rapid Response Systems was dependent on adopting organizational and cultural changes that facilitated staff empowerment, flexible implementation of protocols and ongoing experiential learning. © 2017 John Wiley & Sons Ltd.

49 CFR 807.110 - Self-evaluation.

Science.gov (United States)

2010-10-01

... 49 Transportation 7 2010-10-01 2010-10-01 false Self-evaluation. 807.110 Section 807.110... TRANSPORTATION SAFETY BOARD § 807.110 Self-evaluation. (a) The agency shall, by April 9, 1987, evaluate its... participate in the self-evaluation process by submitting comments (both oral and written). (c) The agency...

18 CFR 344.2 - Manner of submitting quotations.

Science.gov (United States)

2010-04-01

... quotations. 344.2 Section 344.2 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE INTERSTATE COMMERCE ACT FILING QUOTATIONS FOR U.S. GOVERNMENT SHIPMENTS AT REDUCED RATES § 344.2 Manner of submitting quotations. (a) The quotation or tender...

Analysis of suspected wildlife crimes submitted for forensic examinations in Scotland.

Science.gov (United States)

Millins, Caroline; Howie, Fiona; Everitt, Charles; Shand, Michael; Lamm, Catherine

2014-09-01

This study describes the occurrence of suspected wildlife crimes submitted for forensic examination in Scotland in 2010. The study aims were to determine which types of crimes were committed, which species were targeted, and the outcome of investigations, in order to assess the contribution of forensic examinations in the prosecution of wildlife crimes. Information on suspected wildlife crimes submitted between January 1 and December 31, 2010 to the SAC Consulting: Veterinary Services Disease Surveillance Centers, Science and Advice for Scottish Agriculture, and to the University of Glasgow, was used. The location of suspected crimes, the species targeted, cause of death, and types of the 188 submitted wildlife crimes were summarized. More information regarding cases involving birds were submitted than cases involving mammals, and included 114 raptors, 14 waterfowl, and 22 "other bird species." Mammal cases (n = 38) included 12 badgers, 8 foxes, 7 deer, 4 hares, and 7 "other mammals." The cause of death was determined in 124 suspected crimes; malicious or accidental trauma was the most likely cause of death in 72, and 33 were poisoned. Forensic evidence supporting criminal activity was found in 53 cases, and poisoning was the most frequent crime recorded. At least five individuals were successfully prosecuted, representing 2.7 % of submissions. It was challenging to track cases from submission through to prosecution and laboratories conducting forensic investigations were often not informed of the outcome of prosecutions or court decisions.

78 FR 69690 - Draft Guidance for Industry: Considerations for the Design of Early-Phase Clinical Trials of...

Science.gov (United States)

2013-11-20

... (referred to collectively as CGT products) with recommendations to assist in designing early-phase clinical... Fishers Lane, Rm. 1061, Rockville, MD 20852. Submit written requests for single copies of the draft... 20852-1448. Send one self-addressed adhesive label to assist the office in processing your request. The...

Arterial hypertension and associated factors in patients submitted to myocardial revascularization

Directory of Open Access Journals (Sweden)

Flávia Cortez Colósimo

2015-04-01

Full Text Available OBJECTIVE To identify the prevalence of arterial hypertension and associated factors in patients submitted to myocardial revascularization. METHOD Cross-sectional study using the database of a hospital in São Paulo (SP, Brazil containing 3010 patients with coronary artery disease submitted to myocardial revascularization. A multiple logistic regression was performed to identify variables independently associated with hypertension (statistical significance: p1.3: (OR=1.37;CI:1.09-1.72. CONCLUSION A high prevalence of arterial hypertension and association with both non-modifiable and modifiable factors was observed.

Stress analysis in pipelines submitted to internal pressure - and temperature transients

International Nuclear Information System (INIS)

Mansur, T.R.

1981-08-01

Experimental determination of the structural behaviour of a thermal-hydraulic loop, when submitted to simultaneous fast change of pressure and temperature, was performed. For this, electrical strain-gages were positioned at some critical points in order to measure the deformation conditions of the structure. The study of the kinetics of the deformation revealed the presence of important transient stresses, mainly from thermal origin. After this transient behaviour, the structure is submitted to a thermal stress, which is shown to be strongly dependent on the degree of restraint of the structure. (Author) [pt

Automated multivariate analysis of multi-sensor data submitted online: Real-time environmental monitoring.

Science.gov (United States)

Eide, Ingvar; Westad, Frank

2018-01-01

A pilot study demonstrating real-time environmental monitoring with automated multivariate analysis of multi-sensor data submitted online has been performed at the cabled LoVe Ocean Observatory located at 258 m depth 20 km off the coast of Lofoten-Vesterålen, Norway. The major purpose was efficient monitoring of many variables simultaneously and early detection of changes and time-trends in the overall response pattern before changes were evident in individual variables. The pilot study was performed with 12 sensors from May 16 to August 31, 2015. The sensors provided data for chlorophyll, turbidity, conductivity, temperature (three sensors), salinity (calculated from temperature and conductivity), biomass at three different depth intervals (5-50, 50-120, 120-250 m), and current speed measured in two directions (east and north) using two sensors covering different depths with overlap. A total of 88 variables were monitored, 78 from the two current speed sensors. The time-resolution varied, thus the data had to be aligned to a common time resolution. After alignment, the data were interpreted using principal component analysis (PCA). Initially, a calibration model was established using data from May 16 to July 31. The data on current speed from two sensors were subject to two separate PCA models and the score vectors from these two models were combined with the other 10 variables in a multi-block PCA model. The observations from August were projected on the calibration model consecutively one at a time and the result was visualized in a score plot. Automated PCA of multi-sensor data submitted online is illustrated with an attached time-lapse video covering the relative short time period used in the pilot study. Methods for statistical validation, and warning and alarm limits are described. Redundant sensors enable sensor diagnostics and quality assurance. In a future perspective, the concept may be used in integrated environmental monitoring.

1 CFR 457.110 - Self-evaluation.

Science.gov (United States)

2010-01-01

... 1 General Provisions 1 2010-01-01 2010-01-01 false Self-evaluation. 457.110 Section 457.110... PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL CAPITAL PLANNING COMMISSION § 457.110 Self-evaluation. (a... organizations representing handicapped persons, to participate in the self-evaluation process by submitting...

[Early diagnosis and prognosis evaluation of Bell palsy with blink reflex ].

Science.gov (United States)

Xie, Dan-dan; Li, Xiao-song; Liu, Yuan-yuan

2014-11-01

To determine the value of blink reflex in early diagnosis and prognosis evaluation of Bell palsy. Blink reflex and facial nerve conduction were examined in 58 patients with Bell palsy within one week after symptom onset. The patients without response of R1 , R2 and R2 ' waves were classified as complete efferent retardarce (Group A, 30 cases), and those with response of R1 , R2 and R2 ' waves were classified as incomplete efferent anomalies (Group B, 28 cases). The clinical outcomes after three months of systemic therapy were evaluated using the House-Blackmann (H-B) scale. Efferent anomalies of blink reflex occurred in ail of the 58 patients. Abnormal results of facial nerve conduction appeared in 23 (39. 7%) patients. The three months therapy was effective in 93% patients in Group B and 70% patients in Group A (PBell palsy.

22 CFR 711.110 - Self-evaluation.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Self-evaluation. 711.110 Section 711.110 Foreign... CORPORATION § 711.110 Self-evaluation. (a) The agency shall, by September 6, 1989, evaluate its current... participate in the self-evaluation process by submitting comments (both oral and written). (c) The agency...

20 CFR 365.110 - Self-evaluation.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Self-evaluation. 365.110 Section 365.110... § 365.110 Self-evaluation. (a) The agency shall, by December 27, 1989, evaluate its current policies and... self-evaluation process by submitting comments (both oral and written). (c) The agency shall, until at...

29 CFR 100.510 - Self-evaluation.

Science.gov (United States)

2010-07-01

... 29 Labor 2 2010-07-01 2010-07-01 false Self-evaluation. 100.510 Section 100.510 Labor Regulations... § 100.510 Self-evaluation. (a) The agency shall, by September 6, 1989, evaluate its current policies and... participate in the self-evaluation process by submitting comments (both oral and written). (c) The agency...

19 CFR 201.110 - Self-evaluation.

Science.gov (United States)

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Self-evaluation. 201.110 Section 201.110 Customs... Commission § 201.110 Self-evaluation. (a) The agency shall, by April 9, 1987, evaluate its current policies... in the self-evaluation process by submitting comments (both oral and written). (c) The agency shall...

Surgical site infection in patients submitted to heart transplantation.

Science.gov (United States)

Rodrigues, Jussara Aparecida Souza do Nascimento; Ferretti-Rebustini, Renata Eloah de Lucena; Poveda, Vanessa de Brito

2016-08-29

to analyze the occurrence and predisposing factors for surgical site infection in patients submitted to heart transplantation, evaluating the relationship between cases of infections and the variables related to the patient and the surgical procedure. retrospective cohort study, with review of the medical records of patients older than 18 years submitted to heart transplantation. The correlation between variables was evaluated by using Fisher's exact test and Mann-Whitney-Wilcoxon test. the sample consisted of 86 patients, predominantly men, with severe systemic disease, submitted to extensive preoperative hospitalizations. Signs of surgical site infection were observed in 9.3% of transplanted patients, with five (62.5%) superficial incisional, two (25%) deep and one (12.5%) case of organ/space infection. There was no statistically significant association between the variables related to the patient and the surgery. there was no association between the studied variables and the cases of surgical site infection, possibly due to the small number of cases of infection observed in the sample investigated. analisar a ocorrência e os fatores predisponentes para infecção de sítio cirúrgico em pacientes submetidos a transplante cardíaco e verificar a relação entre os casos de infecção e as variáveis referentes ao paciente e ao procedimento cirúrgico. estudo de coorte retrospectivo, com exame dos prontuários médicos de pacientes maiores de 18 anos, submetidos a transplante cardíaco. A correlação entre variáveis foi realizada por meio dos testes exato de Fischer e de Mann-Whitney-Wilcoxon. a amostra foi constituída por 86 pacientes, predominantemente homens, com doença sistêmica grave, submetidos a internações pré-operatórias extensas. Apresentaram sinais de infecção do sítio cirúrgico 9,3% dos transplantados, sendo cinco (62,5%) incisionais superficiais, duas (25%) profundas e um (12,5%) caso de infecção de órgão/espaço. Não houve associa

17 CFR 145.9 - Petition for confidential treatment of information submitted to the Commission.

Science.gov (United States)

2010-04-01

... may summarily reject the submitter's request for confidential treatment with leave to the submitter to... treatment of information submitted to the Commission. 145.9 Section 145.9 Commodity and Securities Exchanges... treatment of information submitted to the Commission. (a) Purpose. This section provides a procedure by...

78 FR 63501 - Request To Submit a Two-Part Application-Northwest Medical Isotopes, LLC

Science.gov (United States)

2013-10-24

... new accident precursors are created by allowing an applicant to submit a construction permit... certain regulatory requirements, which, if granted, would allow the submittal of a construction permit... facility applicants subject to 10 CFR 51.20(b) \\1\\ may submit the information required for a construction...

An attempt of early detection of poor outcome after whiplash

Directory of Open Access Journals (Sweden)

Sebastien LAPORTE

2016-10-01

Full Text Available The main concern with whiplash is that a large proportion of whiplash patients experience disabling symptoms or whiplash associated disorders (WAD for months if not years following the accident. Therefore, identifying early prognostic factors of WAD development is important as WAD have widespread clinical and economic consequences.In order to tackle that question, our study was specifically aimed at combining several methods of investigation in the same WAD patients at the acute stage and six months later. Our longitudinal, open, prospective, multi-center study included 38 whiplash patients, and 13 healthy volunteers matched for age, gender, and socio-economic status with the whiplash group. Whiplash patients were evaluated 15 to 21 days after road accident, and 6 months later. At each appointment, patients underwent a neuropsychological evaluation, a full clinical neurological examination, neurophysiological and postural tests, oto-neurological tests, cervical spine cord Magnetic Resonance Imaging (MRI with tractography (DTI. At 6-month, whiplash patients were categorized into two subgroups based on the results of the Diagnostic and Statistical Manual of Mental Disorders as having either favourable or unfavourable progression (an unfavourable classification corresponding to the presence of Post-Concussion Symptom PCS and we searched retrospectively for early prognostic factors of WAD predicting the passage to chronicity. We found that patients displaying high level of catastrophizing at the acute stage and /or post-traumatic stress disorder associated with either abnormalities in head or trunk kinematics, abnormal test of the otolithic function and at the Equitest or a combination of these syndromes, turned to chronicity. That is, the association of a neuropsychological disorder with a somatic one was sufficient to explain the passage to chronicity. This study suggests that low-grade whiplash patients should be submitted as early as possible

[Pathological neocortical findings in patients with medication-resistant medial temporal lobe epilepsy submitted to surgery].

Science.gov (United States)

Estupiñán-Díaz, B; Morales-Chacón, L M; Lorigados-Pedre, L; García-Maeso, I; Bender-del Busto, J E; Trápaga-Quincoses, O; Hidalgo-Portal, L; García-Navarro, M E; Sánchez-Coroneaux, A; Orozco-Suárez, S

The dual pathology consisting of hippocampal sclerosis plus focal cortical dysplasia (FCD) is often reported in patients with medication-resistant medial temporal lobe epilepsy (MTLE). To determine the histopathological changes that take place in the neocortex of patients with medication-resistant MTLE submitted to surgery and to evaluate the relation between the histopathological changes, pathological background and the clinical course of patients who had received surgical treatment. Tissue obtained by en bloc resection from the neocortex of 18 patients with MTLE refractory to medical treatment was processed histologically and a tailored temporal lobectomy was performed with electrocorticography. Dual pathology was diagnosed in 13 patients (72.2%). Imaging studies confirmed the existence of mesial sclerosis of the temporal in 100% of cases and there was no evidence of neocortical lesions. Histologically, 46.15% and 38.46% of the patients were diagnosed as belonging to FCD type 1a and FCD type 1b, respectively. Only one patient presented FCD type 2a. A statistically significant relation was found between the presence of dual pathology and the existence of an early precipitating injury (p = 0.04). One year after surgery, 72.7% (8/11) patients with dual pathology were classified as belonging to Engel class I. In patients with MTLE there are microscopic FCD-type alterations in the neocortex. There is an association between these alterations and the existence of an initial precipitating injury. Complete resection of the epileptogenic area, which is guaranteed by the lobectomy tailored by electrocorticography, allows patients to enjoy a favourable post-surgical progression one year after surgery.

Survival and ultrastructural features of peach palm (Bactris gasipaes, Kunth) somatic embryos submitted to cryopreservation through vitrification.

Science.gov (United States)

Heringer, Angelo Schuabb; Steinmacher, Douglas André; Schmidt, Éder Carlos; Bouzon, Zenilda Laurita; Guerra, Miguel Pedro

2013-10-01

Bactris gasipaes (Arecaceae), also known as peach palm, was domesticated by Amazonian Indians and is cultivated for its fruit and heart-of-palm, a vegetable grown in the tree's inner core. Currently, the conservation of this species relies on in situ conditions and field gene banks. Complementary conservation strategies, such as those based on in vitro techniques, are indicated in such cases. To establish an appropriate cryopreservation protocol, this study aimed to evaluate the ultrastructural features of B. gasipaes embryogenic cultures submitted to vitrification and subsequent cryogenic temperatures. Accordingly, somatic embryo clusters were submitted to Plant Vitrification Solution 3 (PVS3). In general, cells submitted to PVS3 had viable cell characteristics associated with apparently many mitochondria, prominent nucleus, and preserved cell walls. Cells not incubated in PVS3 did not survive after the cryogenic process in liquid nitrogen. The best incubation time for the vitrification technique was 240 min, resulting in a survival rate of 37 %. In these cases, several features were indicative of quite active cell metabolism, including intact nuclei and preserved cell walls, an apparently many of mitochondria and lipid bodies, and the presence of many starch granules and condensed chromatin. Moreover, ultrastructure analysis revealed that overall cellular structures had been preserved after cryogenic treatment, thus validating the use of vitrification in conjunction with cryopreservation of peach palm elite genotypes, as well as wild genotypes, which carry a rich pool of genes that must be conserved.

Anthropometric and clinical profiles of post-bariatric patients submitted to procedures in plastic surgery.

Science.gov (United States)

Rosa, Simone Corrêa; Macedo, Jefferson Lessa Soares DE; Casulari, Luiz Augusto; Canedo, Lucas Ribeiro; Marques, João Vitor Almeida

2018-01-01

to evaluate the profile of patients submitted to post-bariatric plastic surgery at the North Wing Regional Hospital, Brasília, DF. we conducted a prospective, descriptive and analytical study of patients submitted to Roux-en-Y gastroplasty, and subsequently to plastic surgery, from January 2011 to December 2016. We assessed body mass index before gastroplasty and after surgery plastic surgery, postoperative complications and comorbidities. we studied 139 patients (130 women and nine men), with a mean age of 41 years, who underwent 233 operations. The mean BMI at the time of plastic surgery was 27.44kg/m2. The mean weight loss was 47.02kg and the mean maximum BMI was 45.17kg/m2. The mean time between bariatric surgery and plastic surgery was 42 months. The most important co-morbidities before plastic surgery were arterial hypertension (11.5%), arthropathy (5.4%), diabetes mellitus (5%) and metabolic syndrome (4.3%) (pprofile of post-bariatric patients who underwent plastic surgery was similar to that reported in the literature, except for the low rate of associated surgeries and postoperative complications. Plastic surgery in post-bariatric patients has led to an improvement in the quality of life in most of these patients.

The evidence of the rugoscopy effectiveness as a human identification method in patients submitted to rapid palatal expansion.

Science.gov (United States)

Barbieri, Ana A; Scoralick, Raquel A; Naressi, Suely C M; Moraes, Mari E L; Daruge, Eduardo; Daruge, Eduardo

2013-01-01

The objective of this study was to demonstrate the effectiveness of rugoscopy as a human identification method, even when the patient is submitted to rapid palatal expansion, which in theory would introduce doubt. With this intent, the Rugoscopic Identity was obtained for each subject using the classification formula proposed by Santos based on the intra-oral casts made before and after treatment from patients who were subjected to palatal expansion. The casts were labeled with the patients' initials and randomly arranged for studying. The palatine rugae kept the same patterns in every case studied. The technical error of the intra-evaluator measurement provided a confidence interval of 95%, making rugoscopy a reliable identification method for patients who were submitted to rapid palatal expansion, because even in the presence of intra-oral changes owing to the use of palatal expanders, the palatine rugae retained the biological and technical requirements for the human identification process. © 2012 American Academy of Forensic Sciences.

A Cooperative Plan to Establish an Early Childhood Center for the Invention, Demonstration, and Evaluation of Innovative Practices in Early Childhood Education. Final Report.

Science.gov (United States)

Irondequoit Central School District 3, Rochester, NY.

In 1968 an upstate New York School district, acting on behalf of nine school districts, planned and established an Early Childhood Center. This evaluative report of a 2-year demonstration preschool, modeled on the British Infant School, describes the open classroom arrangement and its effect on the center's children, teachers, and student…

Early-onset behavioral and neurochemical deficits in the genetic mouse model of phenylketonuria.

Science.gov (United States)

Fiori, Elena; Oddi, Diego; Ventura, Rossella; Colamartino, Marco; Valzania, Alessandro; D'Amato, Francesca Romana; Bruinenberg, Vibeke; van der Zee, Eddy; Puglisi-Allegra, Stefano; Pascucci, Tiziana

2017-01-01

Phenylketonuria (PKU) is one of the most common human inborn errors of metabolism, caused by phenylalanine hydroxylase deficiency, leading to high phenylalanine and low tyrosine levels in blood and brain causing profound cognitive disability, if untreated. Since 1960, population is screened for hyperphenylalaninemia shortly after birth and submitted to early treatment in order to prevent the major manifestations of the disease. However, the dietetic regimen (phenylalanine free diet) is difficult to maintain, and despite the recommendation to a strict and lifelong compliance, up to 60% of adolescents partially or totally abandons the treatment. The development and the study of new treatments continue to be sought, taking advantage of preclinical models, the most used of which is the PAHenu2 (BTBR ENU2), the genetic murine model of PKU. To date, adult behavioral and neurochemical alterations have been mainly investigated in ENU2 mice, whereas there are no clear indications about the onset of these deficiencies. Here we investigated and report, for the first time, a comprehensive behavioral and neurochemical assay of the developing ENU2 mice. Overall, our findings demonstrate that ENU2 mice are significantly smaller than WT until pnd 24, present a significant delay in the acquisition of tested developmental reflexes, impaired communicative, motor and social skills, and have early reduced biogenic amine levels in several brain areas. Our results extend the understanding of behavioral and cerebral abnormalities in PKU mice, providing instruments to an early preclinical evaluation of the effects of new treatments.

Early and late oral features of chronic graft-versus-host disease

Directory of Open Access Journals (Sweden)

Alessandra Oliveira Ferrari Gomes

2014-01-01

Full Text Available Background: Chronic graft-versus-host disease is a serious complication of allogeneic hematopoietic cell transplantation, and the mouth is one of the affected sites. Objective: The aim of this study was to evaluate the oral features of this disease after hematopoietic cell transplantation. Methods: This was a cross-sectional multicenter study that enrolled patients submitted to transplantation. Oral evaluations used the National Institutes of Health criteria, salivary flow rates, and the range of mouth opening. Pain and xerostomia were evaluated through a visual analogue scale. Patients were divided into two groups based on the transplantation time (up to one year and more than one year. Results: Of the 57 evaluated recipients, 44 had chronic graft-versus-host disease: ten (22.72% in the group with less than one year after transplantation, and 34 (77.27% in the group with more than one year after transplantation. Lichenoid/hyperkeratotic plaques, erythematous lesions, xerostomia, and hyposalivation were the most commonly reported oral features. Lichenoid/hyperkeratotic plaques were significantly more common in patients within the first year after the transplant. The labial mucosa was affected more in the first year. No significant changes occurred in the frequency of xerostomia, hyposalivation, and reduced mouth opening regarding time after transplantation. Conclusion: Oral chronic graft-versus-host disease lesions were identified early in the course of the disease. The changes observed in salivary gland function and in the range of mouth opening were not correlated with the time after transplantation.

Evaluation of the attentional capacities and working memory of early and late blind persons.

Science.gov (United States)

Pigeon, Caroline; Marin-Lamellet, Claude

2015-02-01

Although attentional processes and working memory seem to be significantly involved in the daily activities (particularly during navigating) of persons who are blind and who use these abilities to compensate for their lack of vision, few studies have investigated these mechanisms in this population. The aim of this study is to evaluate the selective, sustained and divided attention, attentional inhibition and switching and working memory of blind persons. Early blind, late blind and sighted participants completed neuropsychological tests that were designed or adapted to be achievable in the absence of vision. The results revealed that the early blind participants outperformed the sighted ones in selective, sustained and divided attention and working memory tests, and the late blind participants outperformed the sighted participants in selective, sustained and divided attention. However, no differences were found between the blind groups and the sighted group in the attentional inhibition and switching tests. Furthermore, no differences were found between the early and late blind participants in this set of tests. These results suggest that early and late blind persons can compensate for the lack of vision by an enhancement of the attentional and working memory capacities. Copyright © 2014 Elsevier B.V. All rights reserved.

41 CFR 105-50.402 - Reports submitted to the Office of Management and Budget.

Science.gov (United States)

2010-07-01

... Office of Management and Budget. 105-50.402 Section 105-50.402 Public Contracts and Property Management... submitted to the Office of Management and Budget. Copies of the foregoing reports will be submitted by the Administrator to the Office of Management and Budget not later than March 30 of each year. ...

Alberta Learning: Early Development Instrument Pilot Project Evaluation.

Science.gov (United States)

Meaney, Wanda; Harris-Lorenze, Elayne

The Early Development Instrument (EDI) was designed by McMaster University to measure the outcomes of childrens early years as they influence their readiness to learn at school. The EDI was piloted in several Canadian cities in recent years through two national initiatives. Building on these initiatives, Alberta Learning piloted the EDI as a…

Evaluation of Pacific Islands Early Childhood Caries Prevention Project: Republic of the Marshall Islands.

Science.gov (United States)

Milgrom, Peter; Tut, Ohnmar K

2009-01-01

This communication reports an outcomes evaluation of the Pacific Islands Early Childhood Caries Prevention Project. The evaluation includes children in three conditions: a) topical fluoride varnish three times per school year; b) varnish plus twice-per-day toothbrushing; and c) intervention 2 plus three-times-per-day xylitol containing gummy bear snacks at school and home visits to encourage parental involvement. For this evaluation, groups 2 and 3 have been combined. One year after project implementation, mean decayed, extracted, or filled primary teeth was 10.3 [standard deviation (SD)= 4.3] teeth for group 1, and 8.2 (SD = 4.0) teeth for the combination of groups 2 and 3 (P 0.05). Evaluation confirms the outcome of a program including both in-school twice-daily toothbrushing with fluoridated toothpaste and frequent applications of fluoride varnish.

Evaluating the Social Validity of the Early Start Denver Model: A Convergent Mixed Methods Study

Science.gov (United States)

Ogilvie, Emily; McCrudden, Matthew T.

2017-01-01

An intervention has social validity to the extent that it is socially acceptable to participants and stakeholders. This pilot convergent mixed methods study evaluated parents' perceptions of the social validity of the Early Start Denver Model (ESDM), a naturalistic behavioral intervention for children with autism. It focused on whether the parents…

Report of early site suitability evaluation of the potential repository site at Yucca Mountain, Nevada; Yucca Mountain Site Characterization Project

Energy Technology Data Exchange (ETDEWEB)

Younker, J.L.; Andrews, W.B.; Fasano, G.A.; Herrington, C.C.; Mattson, S.R.; Murray, R.C. [Science Applications International Corp., Las Vegas, NV (United States); Ballou, L.B.; Revelli, M.A. [Lawrence Livermore National Lab., CA (United States); Ducharme, A.R.; Shephard, L.E. [Sandia National Labs., Albuquerque, NM (United States); Dudley, W.W.; Hoxie, D.T. [Geological Survey, Denver, CO (United States); Herbst, R.J.; Patera, E.A. [Los Alamos National Lab., NM (United States); Judd, B.R. [Decision Analysis Co., Portola Valley, CA (United States); Docka, J.A.; Rickertsen, L.D. [Weston Technical Associates, Washington, DC (United States)

1992-01-01

This study evaluated the technical suitability of Yucca Mountain, Nevada, as a potential site for a mined geologic repository for the permanent disposal of radioactive waste. The evaluation was conducted primarily to determine early in the site characterization program if there are any features or conditions at the site that indicate it is unsuitable for repository development. A secondary purpose was to determine the status of knowledge in the major technical areas that affect the suitability of the site. This early site suitability evaluation (ESSE) was conducted by a team of technical personnel at the request of the Associate Director of the US Department of Energy (DOE) Office of Geologic Disposal, a unit within the DOE`s Office of Civilian Radioactive Waste Management. The Yucca Mountain site has been the subject of such evaluations for over a decade. In 1983, the site was evaluated as part of a screening process to identify potentially acceptable sites. The site was evaluated in greater detail and found suitable for site characterization as part of the Environmental Assessment (EA) (DOE, 1986) required by the Nuclear Waste Policy Act of 1982 (NWPA). Additional site data were compiled during the preparation of the Site Characterization Plan (SCP) (DOE, 1988a). This early site suitability evaluation has considered information that was used in preparing both-documents, along with recent information obtained since the EA and SCP were published. This body of information is referred to in this report as ``current information`` or ``available evidence.``

10 CFR 4.510 - Self-evaluation.

Science.gov (United States)

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Self-evaluation. 4.510 Section 4.510 Energy NUCLEAR... Programs or Activities Conducted by the U.S. Nuclear Regulatory Commission § 4.510 Self-evaluation. (a) The... representing handicapped persons, to participate in the self-evaluation process by submitting comments (both...

22 CFR 530.110 - Self-evaluation.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Self-evaluation. 530.110 Section 530.110 Foreign... PROGRAMS OR ACTIVITIES CONDUCTED BY THE BROADCASTING BOARD OF GOVERNORS § 530.110 Self-evaluation. (a) The... representing handicapped persons, to participate in the self-evaluation process by submitting comments (both...

20 CFR 703.105 - Copies of forms of policies to be submitted with application.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Copies of forms of policies to be submitted... REGULATIONS Authorization of Insurance Carriers § 703.105 Copies of forms of policies to be submitted with... of the Office copies of the forms of policies which the applicant proposes to issue in writing...

Evaluating Post-Radiotherapy Laryngeal Function with Laryngeal Videostroboscopy in Early Stage Glottic Cancer

Directory of Open Access Journals (Sweden)

Ariel E. Marciscano

2017-06-01

Full Text Available ObjectiveDysphonia is common among patients with early stage glottic cancer. Laryngeal videostroboscopy (LVS has not been routinely used to assess post-radiotherapy (RT voice changes. We hypothesized that LVS would demonstrate improvement in laryngeal function after definitive RT for early-stage glottic cancer.Study designBlinded retrospective review of perceptual voice and stroboscopic parameters for patients with early glottic cancer and controls.SettingHigh-volume, single-institution academic medical center.Subjects and methodsFifteen patients underwent RT for Tis-T2N0M0 glottic cancer and were evaluated with serial LVS exams pre- and post-RT. Stroboscopic assessment included six parameters: vocal fold (VF vibration, VF mobility, erythema/edema, supraglottic compression, glottic closure, and secretions. Grade, roughness, breathiness, asthenia, strain (GRBAS voice perceptual scale was graded in tandem with LVS score. Assessments were grouped by time interval from RT: pre-RT, 0–4, 4–12, and >12 months post-RT.Results60 LVS exams and corresponding GRBAS assessments were reviewed. There were significant improvements in ipsilateral VF motion (P = 0.03 and vibration (P = 0.001 and significant worsening in contralateral VF motion (P < 0.001 and vibration (P = 0.008 at >12 months post-RT. Glottic closure significantly worsened, most prominent >12 months post-RT (P = 0.01. Composite GRBAS scores were significantly improved across all post-RT intervals.ConclusionLVS proved to be a robust tool for assessing pre- and post-RT laryngeal function. We observed post-RT improvement in ipsilateral VF function, a decline in contralateral VF function, and decreased glottic closure. These results demonstrate that LVS can detect meaningful changes in VF and glottic function and support its use for post-RT evaluation of glottic cancer patients.

Evaluation of quantitative sacroiliac scintigraphy for the early detection of sacroiliitis

International Nuclear Information System (INIS)

Prakash, S.; Malaviya, A.N.; Gopinath, P.G.; Bhargava, S.; Mehra, N.K.

1983-01-01

Quantitative sacroliac scintigraphy (QSS) was evaluated for the detection of sacroiliac (SI) joint disease before the appearance of radiographic/changes. QSS with fractional quantitation was done in 13 age- and sexmatched controls and 28 patients with different grades of radiographic sacroliitis. The SI index of each joint was considered separately. The mean SI index values in patients with grade I radiographic sacroiliitis (1.54) and HLA-B27 positive patients with low back pain (1.50) were significantly (P 0.05). Thus a large overlap between the normal and abnormal ranges of sacroiliac ratios limits the utility of quantitative sacroiliac scintigraphy for the early diagnosis of sacroiliac joint disease. (orig.)

49 CFR 551.63 - May a foreign manufacturer submit a designation by email or facsimile?

Science.gov (United States)

2010-10-01

... email or facsimile? 551.63 Section 551.63 Transportation Other Regulations Relating to Transportation... foreign manufacturer submit a designation by email or facsimile? No, the statute requires designation... designation documents submitted via email or facsimile, as they do not satisfy this requirement. ...

Early evaluation of the effects of chemotherapy with longitudinal FDG small-animal PET in human testicular cancer xenografts: early flare response does not reflect refractory disease

Energy Technology Data Exchange (ETDEWEB)

Aide, Nicolas [GRECAN, EA 1772, IFR 146 ICORE, Caen University, Bioticla Unit, Caen (France); Francois Baclesse Comprehensive Cancer Centre, Nuclear Medicine Department, Caen (France); Centre Francois Baclesse, Service de Medecine Nucleaire, Caen Cedex 5 (France); Poulain, Laurent; Briand, Melanie; Dutoit, Soizic; Labiche, Alexandre; Gauduchon, Pascal [GRECAN, EA 1772, IFR 146 ICORE, Caen University, Bioticla Unit, Caen (France); Allouche, Stephane [University Hospital, Biochemistry Department, Caen (France); Ngo-Van Do, Aurelie; Nataf, Valerie; Talbot, Jean-Noel; Montravers, Francoise [Tenon Hospital and University Pierre et Marie Curie (Paris 6), LIMP, Paris (France); Batalla, Alain [Francois Baclesse Comprehensive Cancer Centre, Medical Physics Unit, Caen (France)

2009-03-15

We aimed to evaluate the usefulness of FDG PET in the early prediction of the effects of chemotherapy on human testicular cancer xenografts. Nude rats bearing subcutaneous human embryonal carcinoma xenografts received either cisplatin (5 mg/kg) or saline serum. Small-animal PET studies were performed on days 0, 2, 4 and 7 and compared to immunochemistry studies, flow cytometry studies and hexokinase assays. Cisplatin treatment resulted in biphasic FDG uptake evolution: a peak was observed on day 2, followed by a marked decrease on day 7 despite an insignificant change in tumour volume. Similarly, a peak in cyclin A immunostaining was observed on days 2 and 4, followed by a significant decrease on day 7. Flow cytometry showed that the cyclin A peak was not related to increased cell proliferation but was due to a transient S and G{sub 2}/M cell cycle arrest. A marked increase in cell apoptosis was observed from day 2 to day 7. GLUT-1 showed a significant decrease on day 7. Macrophagic infiltrate remained stable except for an increase observed on day 7. In control tumours, continuous growth was observed, all immunostaining markers remaining stable over time. Hexokinase activity was significantly lower on day 7 in treated tumours than in controls. FDG PET may be useful in the early evaluation of treatment in patients with testicular cancer. In our model, a very early increased [{sup 18}F]-FDG uptake was related to a transient cell cycle arrest and early stage apoptosis but did not reveal refractory disease. (orig.)

Multiscale Alterations in Sugar Cane Bagasse and Straw Submitted to Alkaline Deacetylation

Energy Technology Data Exchange (ETDEWEB)

Lima, Cleilton S. [Brazilian Bioethanol Science and Technology Laboratory (CTBE), Brazilian Center for Research in Energy and Materials (CNPEM), 13083-970 Campinas, São Paulo, Brazil; Department of Biotechnology, Engineering College of Lorena, University of São Paulo, 12602-810 Lorena, São Paulo, Brazil; Rabelo, Sarita C. [Brazilian Bioethanol Science and Technology Laboratory (CTBE), Brazilian Center for Research in Energy and Materials (CNPEM), 13083-970 Campinas, São Paulo, Brazil; Ciesielski, Peter N. [Biosciences Center, National Renewable Energy Laboratory, 15013 Denver West Parkway, Golden, Colorado 80401, United States; Roberto, Inês C. [Department of Biotechnology, Engineering College of Lorena, University of São Paulo, 12602-810 Lorena, São Paulo, Brazil; Rocha, George J. M. [Department of Biotechnology, Engineering College of Lorena, University of São Paulo, 12602-810 Lorena, São Paulo, Brazil; Driemeier, Carlos [Brazilian Bioethanol Science and Technology Laboratory (CTBE), Brazilian Center for Research in Energy and Materials (CNPEM), 13083-970 Campinas, São Paulo, Brazil

2018-01-31

Alkaline deacetylation has emerged as a promising chemistry for pretreatments performed prior to enzymatic saccharification of lignocellulosic biomass. This process avoids complex pressurized reactors and opens new opportunities for lignin covalorization. In this work, we evaluate the chemical and morphological response of sugar cane bagasse and straw submitted to alkaline treatments. Alkaline solutions for deacetylation (0.4% w/w NaOH, 70 degrees C, 3 h) as well as proximal conditions (0.1-0.7% NaOH, 55-85 degrees C, 1-5 h) chosen by 23 experimental design were evaluated. The deacetylation treatment removes ~90% of the acetyl groups and 20-30% of the lignin from both bagasse and straw, while removal of ~20% of the xylan and glucan is observed in straw, but not in bagasse. Considering nanoscale structural alterations, neither cellulose cocrystallization (evaluated by X-ray diffraction) nor formation of lignin aggregates (evaluated by thermoporometric signature) are observed after the alkaline conditions, in contrast to observations after hydrothermal treatments. Furthermore, calorimetric thermoporometry as well as scanning and transmission electron microscopies show substantial introduction of nanoscale porosity and loosening of the tissue and cell wall structures, indicating desirable mechanical weakening and gains in enzyme accessibility. These results provide fundamental and practical knowledge for biorefineries based on alkaline deacetylation of sugar cane bagasse and straw.

45 CFR 606.10 - Self-evaluation.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false Self-evaluation. 606.10 Section 606.10 Public... § 606.10 Self-evaluation. (a) The Foundation shall, within one year of the effective date of this part... with handicaps, to participate in the self-evaluation process by submitting comments (both oral and...

Evaluation of the Early Childhood Oral Health Impact Scale in an Australian preschool child population.

Science.gov (United States)

Arrow, P; Klobas, E

2015-09-01

Early childhood caries has significant impacts on children and their families. The Early Childhood Oral Health Impact Scale (ECOHIS) is an instrument for capturing the complex dimensions of preschool children's oral health. This study aimed to evaluate the reliability and validity of the instrument among Australian preschool children. Parents/children dyads (n = 286) participating in a treatment trial on early childhood caries completed the scale at baseline, and 33 parents repeated the questionnaire 2-3 weeks later. The validity and reliability of the ECOHIS was determined using tests for convergent and discriminant validity, internal reliability of the instrument and test-retest reliability. Scale impacts were strongly correlated with global oral health ratings (Spearman's correlations; r = 0.51, total score; r = 0.43, child impact; and r = 0.49, family impact; p child and the family domains, respectively. Test-retest reliability was 0.92, 0.89 and 0.78 for the total, child and family domains, respectively. The scale demonstrated acceptable validity and reliability for assessing the impact of early childhood caries among Australian preschool children. © 2015 Australian Dental Association.

29 CFR 551.5 - Information to be submitted.

Science.gov (United States)

2010-07-01

... employees compensated under the plan, including information as to the types of goods delivered, their points... application of the plan which are relied upon to support a finding that the plan has the general purpose and... 29 Labor 3 2010-07-01 2010-07-01 false Information to be submitted. 551.5 Section 551.5 Labor...

30 CFR 285.601 - When am I required to submit my plans to MMS?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When am I required to submit my plans to MMS... Information Requirements § 285.601 When am I required to submit my plans to MMS? Your plan submission...) You must provide sufficient data and information with your COP for MMS to complete the needed reviews...

Evaluation of indicators for the early selection of the height character in Musa spp.

Directory of Open Access Journals (Sweden)

Lourdes García Rodríguez

2004-10-01

Full Text Available In the plant breeding programs attended by Biotechnology and using the induction of mutations becomes necessary to work with big populations of plants to guarantee bigger possibilities to be successful in the work. For what to have a selection system that allows to carry out the same one in acclimatization phase would allow to shorten the outlines of improvement and to diminish the population’s size notably to evaluate in field phase, what would bear to diminish the expenses in the whole process of studies clones them. With the aim of determining possible morphological indicators that could be used as markers for the selection of low bearing in the clones of the FHIA were studied in conditions of acclimatization different cultivars and banana mutants, being evaluated several morphological characters as: the height of the plant, number of leaves, long and wide of the penultimate emitted leaf, as well as the long of their petiole and the distance between two serial leaves. It was also evaluated the height of the plants under conditions in vitro when they were subcultivate in a culture medium with different concentration of AG3. The results indicate that inside the evaluated morphological characters, those that more early allowed to distinguish among plants of low bearing were: the long of the petiole and the height of the plants and that the moment of the selection should be to the 60 days. Not differences were observed between genotypes when they were subcultivate in the culture medium enriched with AG3. Key words: banana, early selection, low bearing, morphological markers, plantain

Evaluation of physiotherapy in a prospective cohort of early axial spondyloarthritis. Data from the DESIR cohort.

Science.gov (United States)

Escalas, Cécile; Dalichampt, Marie; Dougados, Maxime; Poiraudeau, Serge

2016-03-01

To evaluate the effect of physiotherapy on functional limitation in an observational cohort of early axial spondyloarthritis. prospective population-based cohort study. 708 patients with early axial spondyloarthritis between 2007 and 2010 naive of TNF blockers. early physiotherapy defined by at least eight supervised sessions of physical therapy during the first six months. the primary outcome was functional improvement defined by a relative improvement of at least 20% in BASFI at six months. Secondary outcomes were improvement in BASFI at one and two years and ASAS20 response criteria at six months. a propensity score of having physiotherapy was developed and multivariate analysis using propensity score weighting were used to assess the effect of physiotherapy on outcome. Overall, 166 (24%) patients had physiotherapy during the first six months. After using propensity score weighting, there was no functional improvement on the primary outcome in patients treated with early physical therapy (relative risk [IC95%]: 1.15 [0.91-1.45]). No differences were observed on secondary outcomes (relative risk [IC95%]: 0.94 [0.80-1.11]). It seems there is no functional benefit for patients with early spondyloarthritis to be treated early by physiotherapy in daily practice, even though the efficacy of physiotherapy has been shown in several randomized controlled studies. Copyright © 2015 Société française de rhumatologie. Published by Elsevier SAS. All rights reserved.

The early emergence of sociomoral evaluation: infants prefer prosocial others.

Science.gov (United States)

Van de Vondervoort, Julia W; Hamlin, J Kiley

2018-04-01

Humans readily evaluate third-parties' prosocial and antisocial acts. Recent evidence reveals that this tendency emerges early in development-even preverbal infants selectively approach prosocial others and avoid antisocial ones. Rather than reflecting attraction toward or away from low-level characteristics of the displays or simple behavioral rules, infants are sensitive to characteristics of both the agents and recipients of prosocial and antisocial acts. Specifically, infants' preferences require that the recipients of positive and negative acts be social agents with clear unfulfilled goals, who have not previously harmed others. In addition, prosocial and antisocial agents must act intentionally, in the service of positive and negative goals. It is an open question whether these prosocial preferences reflect self-interested and/or moral concerns. Copyright © 2017 Elsevier Ltd. All rights reserved.

A longitudinal evaluation of Treponema pallidum PCR testing in early syphilis

Directory of Open Access Journals (Sweden)

Shields Matt

2012-12-01

Full Text Available Abstract Background Syphilis is a growing public health problem among men who have sex with men (MSM globally. Rapid and accurate detection of syphilis is vital to ensure patients and their contacts receive timely treatment and reduce ongoing transmission. Methods We evaluated a PCR assay for the diagnosis of Treponema pallidum using swabs of suspected early syphilis lesions in longitudinally assessed MSM. Results We tested 260 MSM for T pallidum by PCR on 288 occasions: 77 (26.7% had early syphilis that was serologically confirmed at baseline or within six weeks, and 211 (73.3% remained seronegative for syphilis. Of 55 men with primary syphilis, 49 were PCR positive, giving a sensitivity of 89.1% (95% CI: 77.8%-95.9% and a specificity of 99.1% (95% CI: 96.5%-99.9%. Of 22 men with secondary syphilis, 11 were PCR positive, giving a sensitivity of 50% (95% CI: 28.2%-71.8% and a specificity of 100% (95% CI: 66.4%-71.8%. Of the 77 syphilis cases, 43 (56% were HIV positive and the sensitivity and specificity of the PCR test did not vary by HIV status. The PCR test was able to detect up to five (10% primary infections that were initially seronegative, including one HIV positive man with delayed seroconversion to syphilis (72 to 140 days and one HIV positive man who did not seroconvert to syphilis over 14 months follow-up. Both men had been treated for syphilis within a week of the PCR test. Conclusions T pallidum PCR is a potentially powerful tool for the early diagnosis of primary syphilis, particularly where a serological response has yet to develop.

[Non-verbal communication of patients submitted to heart surgery: from awaking after anesthesia to extubation].

Science.gov (United States)

Werlang, Sueli da Cruz; Azzolin, Karina; Moraes, Maria Antonieta; de Souza, Emiliane Nogueira

2008-12-01

Preoperative orientation is an essential tool for patient's communication after surgery. This study had the objective of evaluating non-verbal communication of patients submitted to cardiac surgery from the time of awaking from anesthesia until extubation, after having received preoperative orientation by nurses. A quantitative cross-sectional study was developed in a reference hospital of the state of Rio Grande do Sul, Brazil, from March to July 2006. Data were collected in the pre and post operative periods. A questionnaire to evaluate non-verbal communication on awaking from sedation was applied to a sample of 100 patients. Statistical analysis included Student, Wilcoxon, and Mann Whittney tests. Most of the patients responded satisfactorily to non-verbal communication strategies as instructed on the preoperative orientation. Thus, non-verbal communication based on preoperative orientation was helpful during the awaking period.

Bond strength of resin-resin interfaces contaminated with saliva and submitted to different surface treatments

Directory of Open Access Journals (Sweden)

Adilson Yoshio Furuse

2007-12-01

Full Text Available The purpose of this study was to investigate the effect of different surface treatments on shear bond strength of saliva-contaminated resin-resin interfaces. Flat resin surfaces were fabricated. In the control group, no contamination or surface treatment was performed. The resin surfaces of the experimental groups were contaminated with saliva and air-dried, and then submitted to: (G1 rinsing with water and drying; (G2 application of an adhesive system; (G3 rinsing and drying, abrasion with finishing disks, etching and application of adhesive system; (G4 rinsing and drying, etching, application of silane and adhesive system. Resin cylinders were placed over the treated surfaces. The specimens were stored in water or ethanol. Shear bond strength tests were performed and the mode of failure was evaluated. Data were submitted to two-way ANOVA and Dunnett T3 test. Contamination of resin-resin interfaces with saliva significantly reduced shear strength, especially after prolonged storage (p<0.05. Similar values to the original bond strength were obtained after abrasion and application of adhesive (G3 or etching and application of silane and adhesive (G4. If contamination occurs, a surface treatment is required to guarantee an adequate interaction between the resin increments.

14 CFR 193.5 - How may I submit safety or security information and have it protected from disclosure?

Science.gov (United States)

2010-01-01

... SUBMITTED INFORMATION § 193.5 How may I submit safety or security information and have it protected from... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false How may I submit safety or security information and have it protected from disclosure? 193.5 Section 193.5 Aeronautics and Space FEDERAL AVIATION...

How to submit an ATIP request | IDRC - International Development ...

International Development Research Centre (IDRC) Digital Library (Canada)

Corporations, businesses, and organizations with a Canadian presence have the right to make an access to Information request. Please note that an applicant may be charged additional search fees and/or preparation fees in regards to a request they have submitted under the Access to Information Act.

15 CFR 711.5 - Numerical precision of submitted data.

Science.gov (United States)

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Numerical precision of submitted data. 711.5 Section 711.5 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS...

Imaging evaluation of post pancreatic surgery

International Nuclear Information System (INIS)

Scialpi, Michele; Scaglione, Mariano; Volterrani, Luca; Lupattelli, Luciano; Ragozzino, Alfonso; Romano, Stefania; Rotondo, Antonio

2005-01-01

The role of several imaging techniques in patients submitted to pancreatic surgery with special emphasis to single-slice helical computed tomography (CT) and multidetector-row CT (MDCT) was reviewed. Several surgical options may be performed such as Whipple procedure, distal pancreatectomy, central pancreatectomy, and total pancreatectomy. Ultrasound examination may be used to detect peritoneal fluid in the early post-operative period as well as lesion recurrence in long-term follow-up. Radiological gastrointestinal studies has a major role in evaluation of intestinal functionality. In spite of the advent of other imaging modalities, CT is the most effective after pancreatic surgery. On post-operative CT, the most common findings were small fluid peritoneal or pancreatic collections, stranding of the mesenteric fat with perivascular cuffing, reactive adenopathy and pneumobilia. In addition, CT may demonstrate early (leakage of anastomosis, pancreatico-jejunal fistula, haemorrage, acute pancreatitis of the remnant pancreas, peritonitis), and late (chronic fistula, abscess, aneurysms, anastomotic bilio-digestive stenosis, perianastomotic ulcers, biloma, and intra-abdominal bleeding) surgical complications. In the follow-up evaluation, CT may show tumor recurrence, liver and lymph nodes metastasis. Magnetic resonance may be used as alternative imaging modality to CT, when renal insufficiency or contrast sensitivity prevents the use of iodinated i.v. contrast material or when the biliary tree study is primarily requested. The knowledge of the type of surgical procedures, the proper identification of the anastomoses as well as the normal post-operative imaging appearances are essential for an accurate detection of the complications and recurrent disease

Imaging evaluation of post pancreatic surgery

Energy Technology Data Exchange (ETDEWEB)

Scialpi, Michele [Department of Radiology, ' Santissima Annunziata' Hospital, Via Bruno 1, I-74100 Taranto (Italy)]. E-mail: michelescialpi@libero.it; Scaglione, Mariano [Department of Radiology, ' A. Cardarelli' Hospital, I-80131 Naples (Italy); Volterrani, Luca [Institute of Radiology, University of Siena, I-53100 Siena (Italy); Lupattelli, Luciano [Institute of Radiology, University of Perugia, I-06122 Perugia (Italy); Ragozzino, Alfonso [Department of Radiology, ' A. Cardarelli' Hospital, I-80131 Naples (Italy); Romano, Stefania [Department of Radiology, ' A. Cardarelli' Hospital, I-80131 Naples (Italy); Rotondo, Antonio [Section of Radiology, Department ' Magrassi-Lanzara' , Second University, I-80138 Naples (Italy)

2005-03-01

The role of several imaging techniques in patients submitted to pancreatic surgery with special emphasis to single-slice helical computed tomography (CT) and multidetector-row CT (MDCT) was reviewed. Several surgical options may be performed such as Whipple procedure, distal pancreatectomy, central pancreatectomy, and total pancreatectomy. Ultrasound examination may be used to detect peritoneal fluid in the early post-operative period as well as lesion recurrence in long-term follow-up. Radiological gastrointestinal studies has a major role in evaluation of intestinal functionality. In spite of the advent of other imaging modalities, CT is the most effective after pancreatic surgery. On post-operative CT, the most common findings were small fluid peritoneal or pancreatic collections, stranding of the mesenteric fat with perivascular cuffing, reactive adenopathy and pneumobilia. In addition, CT may demonstrate early (leakage of anastomosis, pancreatico-jejunal fistula, haemorrage, acute pancreatitis of the remnant pancreas, peritonitis), and late (chronic fistula, abscess, aneurysms, anastomotic bilio-digestive stenosis, perianastomotic ulcers, biloma, and intra-abdominal bleeding) surgical complications. In the follow-up evaluation, CT may show tumor recurrence, liver and lymph nodes metastasis. Magnetic resonance may be used as alternative imaging modality to CT, when renal insufficiency or contrast sensitivity prevents the use of iodinated i.v. contrast material or when the biliary tree study is primarily requested. The knowledge of the type of surgical procedures, the proper identification of the anastomoses as well as the normal post-operative imaging appearances are essential for an accurate detection of the complications and recurrent disease.

77 FR 56853 - Submission for OMB Review; Comment Request: Process Evaluation of the Early Independence Award...

Science.gov (United States)

2012-09-14

... respondents is estimated at $9,774. There are no Capital Costs to report. A.12.1--Annualized Estimate of Hour... Collection: Title: Process Evaluation of the Early Independence Award (EIA) Program. Type of Information.... Type of Respondents: Applicants, reviewers, and awardees. The annual reporting burden is as follows...

Evaluating probabilistic dengue risk forecasts from a prototype early warning system for Brazil

Science.gov (United States)

Lowe, Rachel; Coelho, Caio AS; Barcellos, Christovam; Carvalho, Marilia Sá; Catão, Rafael De Castro; Coelho, Giovanini E; Ramalho, Walter Massa; Bailey, Trevor C; Stephenson, David B; Rodó, Xavier

2016-01-01

Recently, a prototype dengue early warning system was developed to produce probabilistic forecasts of dengue risk three months ahead of the 2014 World Cup in Brazil. Here, we evaluate the categorical dengue forecasts across all microregions in Brazil, using dengue cases reported in June 2014 to validate the model. We also compare the forecast model framework to a null model, based on seasonal averages of previously observed dengue incidence. When considering the ability of the two models to predict high dengue risk across Brazil, the forecast model produced more hits and fewer missed events than the null model, with a hit rate of 57% for the forecast model compared to 33% for the null model. This early warning model framework may be useful to public health services, not only ahead of mass gatherings, but also before the peak dengue season each year, to control potentially explosive dengue epidemics. DOI: http://dx.doi.org/10.7554/eLife.11285.001 PMID:26910315

48 CFR 225.7703-3 - Evaluating offers.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Evaluating offers. 225... Iraq or Afghanistan 225.7703-3 Evaluating offers. (a) Evaluate offers submitted in response to... Afghanistan, as follows: (1) If the low offer is an offer of a product or service from Iraq or Afghanistan...

News from the Library: Share your work, submit your thesis to CDS!

CERN Multimedia

CERN Library

2011-01-01

Are you a student paid by CERN, using CERN equipment or advised by CERN staff and you are currently writing a thesis? Then you should know that you are welcome to submit your final work to the CERN Document Server (CDS), where it will be made available by Open Access.   This is the most efficient way of sharing your work within the community - your thesis will certainly find a much greater audience than if you follow the advice of certain dubious publishing companies (see the article Free access to science... but at what cost? published in this issue). At the same time, you ensure long-term storage of your file. All theses qualify, from bachelor to PhD, and any language is accepted. You simply go to CDS and submit your work. If your thesis was written some years ago it is still not too late to submit it; it will then get a new life on CDS! More information here. CERN Theses collection here. If you have any questions or submission problems, please do not hesitate to contact Catherine Cart. ...

Detection of early osteoarthritis in the centrodistal joints of Icelandic horses: Evaluation of radiography and low-field magnetic resonance imaging.

Science.gov (United States)

Ley, C J; Björnsdóttir, S; Ekman, S; Boyde, A; Hansson, K

2016-01-01

Validated noninvasive detection methods for early osteoarthritis (OA) are required for OA prevention and early intervention treatment strategies. To evaluate radiography and low-field magnetic resonance imaging (MRI) for the detection of early stage OA osteochondral lesions in equine centrodistal joints using microscopy as the reference standard. Prospective imaging of live horses and imaging and microscopy of cadaver tarsal joints. Centrodistal (distal intertarsal) joints of 38 Icelandic research horses aged 27-29 months were radiographed. Horses were subjected to euthanasia approximately 2 months later and cadaver joints examined with low-field MRI. Osteochondral joint specimens were classified as negative or positive for OA using light microscopy histology or scanning electron microscopy. Radiographs and MRIs were evaluated for osteochondral lesions and results compared with microscopy. Forty-two joints were classified OA positive with microscopy. Associations were detected between microscopic OA and the radiography lesion categories; mineralisation front defect (Pradiography and low-field MRI pooled lesion categories, but radiography was often superior when individual lesion categories were compared. Early stage centrodistal joint OA changes may be detected with radiography and low-field MRI. Detection of mineralisation front defects in radiographs may be a useful screening method for detection of early OA in centrodistal joints of young Icelandic horses. © 2015 EVJ Ltd.

36 CFR 1206.86 - What additional materials must I submit with the final narrative report?

Science.gov (United States)

2010-07-01

... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false What additional materials must I submit with the final narrative report? 1206.86 Section 1206.86 Parks, Forests, and Public... narrative report? You must submit the materials determined by the Commission as found in the NHPRC grant...

78 FR 72099 - Agency Information Collection Activities: Submitted for Office of Management and Budget Review...

Science.gov (United States)

2013-12-02

... January 2, 2014 for the assurance of consideration. ADDRESSES: Submit comments to the Office of... submitted is subject to subsequent audit and adjustment. A. Federal Oil and Gas Valuation Regulations The... allow or not allow one or both of the relief options . . . (d) If a State decides in advance . . . that...

Early evaluation of renal hemodynamic alterations in type I diabetes mellitus with duplex ultrasound

Directory of Open Access Journals (Sweden)

Saif Aasem

2010-01-01

Full Text Available To evaluate the role of renal duplex ultrasonography in the detection of early alte-ration of renal blood flow in type I diabetic patients, we studied with duplex ultrasound 32 patients with type I diabetes mellitus (19 males, 13 females, age range 8-19 years and 35 age and sex-matched controls. The resistivity indices (RIs and pulsatility indices (PIs of the main renal as well as intra-renal arteries were calculated. Compared with the healthy control subjects, diabetic patients had significantly higher resistivity indices (RIs in the intrarenal (segmental, arcuate and interlobar ar-teries (P= 0.001. The study, also revealed a significantly positive correlation between the RIs in the intrarenal arteries in diabetics and the albumin/creatinine ratio (r= 0.54, 0.52 and 0.51 respectively, glycated hemoglobin (r= 0.61, 0.59 and 0.63 respectively, as well as the estimated GFR (e-GFR (r= 0.53, 0.51 and 0.57 respectively. We conclude that the current study documented early intra-renal hemodynamic alterations in the form of pathologically elevated intrarenal RIs. This denotes the potential usefulness of duplex evaluation of the intrarenal arteries, as a noninvasive procedure, for monitoring type 1 diabetic patients to predict those at risk of diabetic nephropathy.

Employment and educational outcomes in early intervention programmes for early psychosis: a systematic review.

Science.gov (United States)

Bond, G R; Drake, R E; Luciano, A

2015-10-01

Young adults with early psychosis want to pursue normal roles - education and employment. This paper summarises the empirical literature on the effectiveness of early intervention programmes for employment and education outcomes. We conducted a systematic review of employment/education outcomes for early intervention programmes, distinguishing three programme types: (1) those providing supported employment, (2) those providing unspecified vocational services and (3) those without vocational services. We summarised findings for 28 studies. Eleven studies evaluated early intervention programmes providing supported employment. In eight studies that reported employment outcomes separately from education outcomes, the employment rate during follow-up for supported employment patients was 49%, compared with 29% for patients receiving usual services. The two groups did not differ on enrolment in education. In four controlled studies, meta-analysis showed that the employment rate for supported employment participants was significantly higher than for control participants, odds ratio = 3.66 [1.93-6.93], p < 0.0001. Five studies (four descriptive and one quasi-experimental) of early intervention programmes evaluating unspecified vocational services were inconclusive. Twelve studies of early intervention programmes without vocational services were methodologically heterogeneous, using diverse methods for evaluating vocational/educational outcomes and precluding a satisfactory meta-analytic synthesis. Among studies with comparison groups, 7 of 11 (64%) reported significant vocational/education outcomes favouring early intervention over usual services. In early intervention programmes, supported employment moderately increases employment rates but not rates of enrolment in education. These improvements are in addition to the modest effects early programmes alone have on vocational/educational outcomes compared with usual services.

76 FR 67729 - Information Collection Being Submitted for Review and Approval to the Office of Management and...

Science.gov (United States)

2011-11-02

... operators submit this form to local franchising authorities or the Commission, in situations where the FCC... changes in external costs. Cable operators submit FCC Form 1240 to their respective local franchising...

EVALUATION OF SYMMETRIC DIMETHYLARGININE AS AN EARLY BIOMARKER OF CHRONIC KIDNEY DISEASE IN CAPTIVE CHEETAHS (ACINONYX JUBATUS).

Science.gov (United States)

Lamglait, Benjamin; Vandenbunder-Beltrame, Marielle

2017-09-01

Symmetric dimethylarginine (SDMA) has been shown to be a valuable biomarker for early detection of chronic kidney disease (CKD) in canine and feline patients. Recognition of early (subclinical) kidney disease would be of value in cheetahs (Acinonyx jubatus) as prevalence of CKD is relatively high in this species in captivity. Fifty-eight banked serum and plasma samples from seven adult cheetahs that died of CKD were analyzed for creatinine, urea, and SDMA. A marked increase in SDMA was noted on five of the tested cheetahs earlier than the rise of serum creatinine and urea (estimated 8-35 mo; mean 21.4 mo; median 22 mo). SDMA appears as an early biomarker to evaluate renal function for the diagnosis of CKD in cheetahs regardless of the cause of this disease.

Clinical Leaders for the Future: Evaluation of the Early Clinical Careers Fellowship Pilot Programme

OpenAIRE

Pearson, Pauline; Machin, Alison; Rae, Anne

2010-01-01

The aim of this study was to systematically evaluate key features (contexts), activities (mechanisms) and outcomes of the Early Clinical Career Fellowships Pilot. In Scotland and across the United Kingdom (UK) the number of nurses likely to retire is set to double between 2005 and 2015 - equivalent to a quarter of all nurses. There is a need to build leadership capacity within the existing workforce in order to maintain the quality of service provision.

Evaluation of the attentional capacities and working memory of early and late blind persons

OpenAIRE

PIGEON, Caroline; MARIN-LAMELLET, Claude

2015-01-01

Although attentional processes and working memory seem to be significantly involved in the daily activities (particularly during navigating) of persons who are blind and who use these abilities to compensate for their lack of vision, few studies have investigated these mechanisms in this population. The aim of this study is to evaluate the selective, sustained and divided attention, attentional inhibition and switching and working memory of blind persons. Early blind, late blind and sighted p...

13 CFR 120.830 - Reports a CDC must submit.

Science.gov (United States)

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Reports a CDC must submit. 120.830 Section 120.830 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Development... each new associate and staff, a Statement of Personal History (for use by non-bank lenders and CDCs...

42 CFR 1008.11 - Who may submit a request.

Science.gov (United States)

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false Who may submit a request. 1008.11 Section 1008.11 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OIG... advisory opinion regarding an existing arrangement or one which the requestor in good faith specifically...

78 FR 63183 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request; Mobile...

Science.gov (United States)

2013-10-23

... promulgated under SNAP require that Motor Vehicle Air Conditioners (MVACs) retrofitted to use a SNAP... Request Submitted to OMB for Review and Approval; Comment Request; Mobile Air Conditioner Retrofitting... Environmental Protection Agency has submitted an information collection request (ICR), Mobile Air Conditioner...

Automated multivariate analysis of multi-sensor data submitted online: Real-time environmental monitoring.

Directory of Open Access Journals (Sweden)

Ingvar Eide

Full Text Available A pilot study demonstrating real-time environmental monitoring with automated multivariate analysis of multi-sensor data submitted online has been performed at the cabled LoVe Ocean Observatory located at 258 m depth 20 km off the coast of Lofoten-Vesterålen, Norway. The major purpose was efficient monitoring of many variables simultaneously and early detection of changes and time-trends in the overall response pattern before changes were evident in individual variables. The pilot study was performed with 12 sensors from May 16 to August 31, 2015. The sensors provided data for chlorophyll, turbidity, conductivity, temperature (three sensors, salinity (calculated from temperature and conductivity, biomass at three different depth intervals (5-50, 50-120, 120-250 m, and current speed measured in two directions (east and north using two sensors covering different depths with overlap. A total of 88 variables were monitored, 78 from the two current speed sensors. The time-resolution varied, thus the data had to be aligned to a common time resolution. After alignment, the data were interpreted using principal component analysis (PCA. Initially, a calibration model was established using data from May 16 to July 31. The data on current speed from two sensors were subject to two separate PCA models and the score vectors from these two models were combined with the other 10 variables in a multi-block PCA model. The observations from August were projected on the calibration model consecutively one at a time and the result was visualized in a score plot. Automated PCA of multi-sensor data submitted online is illustrated with an attached time-lapse video covering the relative short time period used in the pilot study. Methods for statistical validation, and warning and alarm limits are described. Redundant sensors enable sensor diagnostics and quality assurance. In a future perspective, the concept may be used in integrated environmental monitoring.

Application evaluation of MR diffusion weighted imaging in the diagnosis and differential diagnosis of early prostate cancer

International Nuclear Information System (INIS)

Shen Junkang; Lu Yanli; Yang Yi; Zhao Wenlu; Jiang Zhen; Zhang Caiyuan; Ma Qi; Zhang Yongsheng; Shan Yuxi

2014-01-01

Objective: To evaluate the value of diffusion weighted imaging (DWI) in the diagnosis and differential diagnosis of early prostate cancer. Methods: The data of 106 patients [35 with early prostate cancer (PCa), 55 with benign prostatic hyperplasia (BPH) and 16 with prostatitis] were retrospectively analyzed, who underwent T 2 WI, DWI, and T 2 WI + DWI examination and all patients were confirmed by pathology. The data obtained from T 2 WI, DWI, and a combination of T 2 WI and DWI were scored and compared with pathological findings. The receiver operating characteristic (ROC) curves were analyzed for the area under the curve (Az) using Z test. Specificities, sensitivities and accuracies of the three protocols to diagnose PCa were evaluated. The ADC values of each prostate lesion were measured and compared with ANOVA test. Results: DWI missed 7 in 35 early prostate cancer, misdiagnosed 2 in 55 BPH, and 11 in 16 prostatitis. The Az values of T 2 WI, DWI, and T 2 WI + DWI for the detection of early prostate cancer were 0.846, 0.874, and 0.947, respectively. There was significant differences between T 2 WI + DWI and T 2 WI alone (Z=3.262, P=0.001), and between T 2 WI + DWI and DWI alone (Z=2.402, P=0.016). There was no significant difference between T 2 WI alone and DWI alone (Z=0.630, P=0.528). The sensitivities, specificities, and accuracies of T 2 WI, DWI, and a combination of T 2 WI and DWI for the detection of early prostate cancer were 51.43% (18/35), 80.00% (28/35), and 85.71% (30/35); 90.14% (64/71), 81.69% (58/71), and 88.73% (63/71); 77.36% (82/106), 81.13% (86/106), and 87.74% (93/106) respectively. The ADC values for detecting early PCa, BPH, and prostatitis were (723 ± 183) ×10 -3 , (1 381 ± 117) × 10 -3 , and (957 ± 175) × 10 -3 mm 2 /s.These ADC values showed statistical significance (F=131.94, P<0.01) among the three groups and also reached statistical significance between each two groups. Conclusions: DWI is valuable in detecting early prostate

48 CFR 1352.213-71 - Instructions for submitting quotations under the simplified acquisition threshold-non-commercial.

Science.gov (United States)

2010-10-01

... submitting quotations under the simplified acquisition threshold-non-commercial. 1352.213-71 Section 1352.213... quotations under the simplified acquisition threshold—non-commercial. As prescribed in 48 CFR 1313.302-1-70, insert the following provision: Instructions for Submitting Quotations Under the Simplified Acquisition...

Macronutrients accumulation and growth of pineapple cultivars submitted to aluminum stress

Directory of Open Access Journals (Sweden)

Mauro F. C. Mota

Full Text Available ABSTRACT The objective was to determine the growth and accumulation of macronutrients of two pineapple cultivars submitted to different concentrations of aluminum (Al. For this, a study was conducted in plastic pots containing 4 L of nutrient solution, in a randomized block design, in a 2 x 5 factorial scheme, corresponding to two pineapple cultivars (‘IAC Fantástico’ and ‘Vitória’ and five Al concentrations (0, 21.6, 43.2, 64.8 and 86.4 mg of Al plant-1, with four replicates. The following variables were evaluated: root length, dry matter of root, stem and leaf, stem diameter, number of leaves, chlorophyll content and accumulation of macronutrients at 60 days after treatment. The cv. ‘Vitória’ showed a linear decrease in chlorophyll content, root dry matter, root length and accumulation of N, P, K, Ca and Mg in most plant components promoted by the increase of Al concentration in the nutrient solution. The cv. ‘IAC Fantástico’ had lower total dry matter, stem dry matter, stem diameter and accumulation of N, Ca and Mg. However, the evaluated characteristics were not influenced by the increase of Al concentration, showing greater tolerance of this cultivar to Al in nutrient solution.

A Critical Review of Personal Statements Submitted by Dermatology Residency Applicants

Directory of Open Access Journals (Sweden)

Jeannette Olazagasti

2014-01-01

Full Text Available Background. A strong personal statement is deemed favorable in the overall application review process. However, research on the role of personal statements in the application process is lacking. Objective. To determine if personal statements from matched applicants differ from unmatched applicants. Methods. All dermatology residency applications (n=332 submitted to UC Davis Dermatology in the year of 2012 were evaluated. Two investigators identified the characteristics and recurring themes of content present in the personal statements. Then, both investigators individually evaluated the content of these personal statements in order to determine if any of the defined themes was present. Chi-square, Fisher’s exact, and reliability tests were used. Results. The following themes were emphasized more often by the matched applicants than the unmatched applicants as their reasons for going into dermatology are to study the cutaneous manifestations of systemic disease (33.8% versus 22.8%, to contribute to the literature gap (8.3% versus 1.1%, and to study the pathophysiology of skin diseases (8.3% versus 2.2%; P≤0.05 for all. Conclusion. The prevalence of certain themes in personal statements of dermatology applicants differs according to match status; nevertheless, whether certain themes impact match outcome needs to be further elucidated.

40 CFR 63.4910 - What notifications must I submit?

Science.gov (United States)

2010-07-01

..., accuracy, and completeness of the report. Such certifications must also comply with the requirements of 40... need to submit copies of any test reports. (i) Mass fraction of organic HAP for one coating, for one... mass of organic HAP contained in the waste materials for which you are claiming an allowance in...

Rectal dose assessment in patients submitted to high-dose-rate brachytherapy for uterine cervix cancer; Avaliacao da dose no reto em pacientes submetidas a braquiterapia de alta taxa de dose para o tratamento do cancer do colo uterino

Energy Technology Data Exchange (ETDEWEB)

Oliveira, Jetro Pereira de [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Faculdade de Medicina; Rosa, Luiz Antonio Ribeiro da [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil)], e-mail: lrosa@ird.gov.br; Batista, Delano Valdivino Santos; Bardella, Lucia Helena [Instituto Nacional de Cancer (INCA), Rio de Janeiro, RJ (Brazil). Unit of Medical Physics; Carvalho, Arnaldo Rangel [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil). Lab. of Thermoluminescent Dosimetry

2009-03-15

Objective: The present study was aimed at developing a thermoluminescent dosimetric system capable of assessing the doses delivered to the rectum of patients submitted to high-dose-rate brachytherapy for uterine cervix cancer. Materials and methods: LiF:Mg,Ti,Na powder was the thermoluminescent material utilized for evaluating the rectal dose. The powder was divided into small portions (34 mg) which were accommodated in a capillary tube. This tube was placed into a rectal probe that was introduced into the patient's rectum. Results: The doses delivered to the rectum of six patients submitted to high-dose-rate brachytherapy for uterine cervix cancer evaluated by means of thermoluminescent dosimeters presented a good agreement with the planned values based on two orthogonal (anteroposterior and lateral) radiographic images of the patients. Conclusion: The thermoluminescent dosimetric system developed in the present study is simple and easy to be utilized as compared to other rectal dosimetry methods. The system has shown to be effective in the evaluation of rectal doses in patients submitted to high-dose-rate brachytherapy for uterine cervix cancer. (author)

CD68+ cell count, early evaluation with PET and plasma TARC levels predict response in Hodgkin lymphoma.

Science.gov (United States)

Cuccaro, Annarosa; Annunziata, Salvatore; Cupelli, Elisa; Martini, Maurizio; Calcagni, Maria L; Rufini, Vittoria; Giachelia, Manuela; Bartolomei, Francesca; Galli, Eugenio; D'Alò, Francesco; Voso, Maria T; Leone, Giuseppe; Giordano, Alessandro; Larocca, Luigi M; Hohaus, Stefan

2016-03-01

Early response evaluation with [(18) F]fluordeoxyglucose (FDG) positron emission tomography after 2 cycles of chemotherapy (interim PET) has been indicated as the strongest predictor for outcome in classical Hodgkin lymphoma (HL). We studied the prognostic role of the number of tumor-infiltrating CD68+ cells and of the plasma levels of TARC (thymus and activation-regulated chemokine) in the context of interim PET in 102 patients with classical HL treated with Adriamycin, Bleomycin, Vinblastine, Dacarbazine (ABVD). After 2 ABVD cycles, interim PET according to Deauville criteria was negative (score 0-3) in 85 patients and positive (score 4-5) in 15 patients (2 patients technically not evaluable). TARC levels were elevated in 89% of patients at diagnosis, and decreased after 2 cycles in 82% of patients. Persistently elevated TARC levels in 18% of patients were significantly associated with a positive PET result (P = 0.007). Strong predictors for progression-free survival (PFS) were a negative interim PET (85% vs. 28%, P evaluation had no prognostic role. In multivariate analysis, interim PET, CD68+ cell counts and presence of B-symptoms were independently associated with PFS. We conclude that although TARC levels are a biomarker for early response evaluation, they cannot substitute for interim PET as outcome predictor in HL. The evaluation of CD68 counts and B-symptoms at diagnosis may help to identify low-risk patients regardless positive interim PET. © 2016 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

Early Pseudoprogression following Chemoradiotherapy in Glioblastoma Patients: The Value of RANO Evaluation

Directory of Open Access Journals (Sweden)

Paulo Linhares

2013-01-01

Full Text Available Introduction. The aim of this study was to determine the frequency of pseudoprogression in a cohort of glioblastoma (GBM patients following radiotherapy/temozolomide (RT/TMZ by comparing Macdonald criterial to Response Assessment in Neuro-Oncology (RANO criteria. The impact on prognosis and survival analysis was also studied. Materials and Methods. All patients receiving RT/TMZ for newly diagnosed GBM from January 2005 to December 2009 were retrospectively evaluated, and demographic, clinical, radiographic, treatment, and survival data were reviewed. Updated RANO criteria were used for the evaluation of the pre-RT and post-RT MRI and compared to classic Macdonald criteria. Survival data was evaluated using the Kaplan-Meier and log-rank analysis. Results and Discussion. 70 patients were available for full radiological response assessment. Early progression was confirmed in 42 patients (60% according to Macdonald criteria and 15 patients (21% according to RANO criteria. Pseudoprogression was identified in 10 (23.8% or 2 (13.3% patients in Macdonald and RANO groups, respectively. Cumulative survival of pseudoprogression group was higher than that of true progression group and not statistically different from the non-progressive disease group. Conclusion. In this cohort, the frequency of pseudoprogression varied between 13% and 24%, being overdiagnosed by older Macdonald criteria, which emphasizes the importance of RANO criteria and new radiological biomarkers for correct response evaluation.

Effect of ionizing radiation on the taste function of patients submitted to head and neck radiotherapy

International Nuclear Information System (INIS)

Silva, Amaro Ilidio Vespasiano; Galante, Celio

2011-01-01

Objective: to evaluate the effects of ionizing radiation on the taste function in patients submitted to radiotherapy in the head and neck region. Materials and methods: twenty patients diagnosed with head and neck tumors and undergoing treatment in the Division of Radiotherapy at Santa Casa de Misericordia de Belo Horizonte, MG, Brazil, were selected. For their taste function testing, four solutions were manipulated with salt (NaCl), sugar (sucrose), citric acid (for acidity), and urea (for bitterness), at three different (low, medium and high) concentrations. Weekly tests were performed during the first three weeks of radiotherapy, with random administration of the solutions (three drops each) respecting the order of their concentration levels (low, medium and high). After the application of each solution, the patient reported which flavor he/she tasted. Results: a statistically significant difference was observed in the loss of taste function as the results in the 1st and 4th weeks of treatment were compared, with salty solution at the three concentration levels, with the sweet solution at low and medium concentrations, and with the sour and bitter solutions, only at low concentration. Conclusion: ionizing radiation alters the taste function of patients submitted to head and neck radiotherapy. (author)

Effect of ionizing radiation on the taste function of patients submitted to head and neck radiotherapy

Energy Technology Data Exchange (ETDEWEB)

Silva, Amaro Ilidio Vespasiano [Universidade Estadual de Campinas (UNICAMP), SP (Brazil); Galante, Celio [Santa Casa de Misericordia de Belo Horizonte, MG (Brazil). Div. de Radioterapia; Manzi, Flavio Ricardo, E-mail: manzi@pucminas.b [Pontificia Universidade Catolica de Minas Gerais (PUC-MG), Belo Horizonte, MG (Brazil)

2011-09-15

Objective: to evaluate the effects of ionizing radiation on the taste function in patients submitted to radiotherapy in the head and neck region. Materials and methods: twenty patients diagnosed with head and neck tumors and undergoing treatment in the Division of Radiotherapy at Santa Casa de Misericordia de Belo Horizonte, MG, Brazil, were selected. For their taste function testing, four solutions were manipulated with salt (NaCl), sugar (sucrose), citric acid (for acidity), and urea (for bitterness), at three different (low, medium and high) concentrations. Weekly tests were performed during the first three weeks of radiotherapy, with random administration of the solutions (three drops each) respecting the order of their concentration levels (low, medium and high). After the application of each solution, the patient reported which flavor he/she tasted. Results: a statistically significant difference was observed in the loss of taste function as the results in the 1st and 4th weeks of treatment were compared, with salty solution at the three concentration levels, with the sweet solution at low and medium concentrations, and with the sour and bitter solutions, only at low concentration. Conclusion: ionizing radiation alters the taste function of patients submitted to head and neck radiotherapy. (author)

An analysis of the titles of papers submitted to the UK REF in 2014: authors, disciplines, and stylistic details

OpenAIRE

Hudson, John

2016-01-01

In 2014 over 52,000 academics submitted >155,500 journal articles in 36 different disciplines for assessment in the UK?s four-year Research Evaluation Framework (the REF). In this paper the characteristics of the titles of these papers are assessed. Although these varied considerably between the disciplines, the main findings were that: (i) the lengths of the titles increased with the number of authors in almost all disciplines, (ii) the use of colons and question marks tended to decline with...

Pressure vessels supported in the soil submitted to axissymetrical loads

International Nuclear Information System (INIS)

Gouvea, J.P. de; Bevilacqua, L.

1982-01-01

A pressure vessel, spherical segment or vertical cylinder, is supported in the soil and submitted to axissymetrical loads. The soil is considered as a semi-infinite elastic solid and the support as a lattice. The method of rigidity is used. (E.G.) [pt

41 CFR 301-75.205 - Is the interviewee required to submit a travel claim to us?

Science.gov (United States)

2010-07-01

... required to submit a travel claim to us? 301-75.205 Section 301-75.205 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES AGENCY RESPONSIBILITIES 75... reimbursed, then he or she must submit a travel claim in accordance with your agency procedures in order to...

20 CFR 641.310 - May the Governor delegate responsibility for developing and submitting the State Plan?

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false May the Governor delegate responsibility for developing and submitting the State Plan? 641.310 Section 641.310 Employees' Benefits EMPLOYMENT AND TRAINING... developing and submitting the State Plan, provided that any such delegation is consistent with State law and...

Cardioprotective effects of early and late aerobic exercise training in experimental pulmonary arterial hypertension.

Science.gov (United States)

Moreira-Gonçalves, Daniel; Ferreira, Rita; Fonseca, Hélder; Padrão, Ana Isabel; Moreno, Nuno; Silva, Ana Filipa; Vasques-Nóvoa, Francisco; Gonçalves, Nádia; Vieira, Sara; Santos, Mário; Amado, Francisco; Duarte, José Alberto; Leite-Moreira, Adelino F; Henriques-Coelho, Tiago

2015-11-01

Clinical studies suggest that aerobic exercise can exert beneficial effects in pulmonary arterial hypertension (PAH), but the underlying mechanisms are largely unknown. We compared the impact of early or late aerobic exercise training on right ventricular function, remodeling and survival in experimental PAH. Male Wistar rats were submitted to normal cage activity (SED), exercise training in early (EarlyEX) and in late stage (LateEX) of PAH induced by monocrotaline (MCT, 60 mg/kg). Both exercise interventions resulted in improved cardiac function despite persistent right pressure-overload, increased exercise tolerance and survival, with greater benefits in EarlyEX+MCT. This was accompanied by improvements in the markers of cardiac remodeling (SERCA2a), neurohumoral activation (lower endothelin-1, brain natriuretic peptide and preserved vascular endothelial growth factor mRNA), metabolism and mitochondrial oxidative stress in both exercise interventions. EarlyEX+MCT provided additional improvements in fibrosis, tumor necrosis factor-alpha/interleukin-10 and brain natriuretic peptide mRNA, and beta/alpha myosin heavy chain protein expression. The present study demonstrates important cardioprotective effects of aerobic exercise in experimental PAH, with greater benefits obtained when exercise training is initiated at an early stage of the disease.

Estimation for aerial detection effectiveness with cooperation efficiency factors of early-warning aircraft in early-warning detection SoS under BSC framework

Science.gov (United States)

Zhu, Feng; Hu, Xiaofeng; He, Xiaoyuan; Guo, Rui; Li, Kaiming; Yang, Lu

2017-11-01

In the military field, the performance evaluation of early-warning aircraft deployment or construction is always an important problem needing to be explored. As an effective approach of enterprise management and performance evaluation, Balanced Score Card (BSC) attracts more and more attentions and is studied more and more widely all over the world. It can also bring feasible ideas and technical approaches for studying the issue of the performance evaluation of the deployment or construction of early-warning aircraft which is the important component in early-warning detection system of systems (SoS). Therefore, the deep explored researches are carried out based on the previously research works. On the basis of the characteristics of space exploration and aerial detection effectiveness of early-warning detection SoS and the cardinal principle of BSC are analyzed simply, and the performance evaluation framework of the deployment or construction of early-warning aircraft is given, under this framework, aimed at the evaluation issue of aerial detection effectiveness of early-warning detection SoS with the cooperation efficiency factors of the early-warning aircraft and other land based radars, the evaluation indexes are further designed and the relative evaluation model is further established, especially the evaluation radar chart being also drawn to obtain the evaluation results from a direct sight angle. Finally, some practical computer simulations are launched to prove the validity and feasibility of the research thinking and technologic approaches which are proposed in the paper.

24 CFR 220.821 - Items to be filed on submitting claim.

Science.gov (United States)

2010-04-01

... filed on submitting claim. Within 30 days after the filing of the notice of intention to file claim, or... principal of the mortgage indebtedness; (h) All records, ledger cards, documents, books, papers and accounts...

Acceptance rate and reasons for rejection of manuscripts submitted to Veterinary Radiology & Ultrasound during 2012.

Science.gov (United States)

Lamb, Christopher R; Mai, Wilfried

2015-01-01

Better understanding of the reasons why manuscripts are rejected, and recognition of the most frequent manuscript flaws identified by reviewers, should help submitting authors to avoid these pitfalls. Of 219 manuscripts submitted to Veterinary Radiology & Ultrasound in 2012, none (0%) was accepted without revision, four (2%) were withdrawn by the authors, 99 (45%) were accepted after revision, and 116 (53%) were rejected. All manuscripts for which minor revision was requested, and 73/86 (85%) manuscripts for which major revision was requested, were ultimately accepted. Acceptance rate was greater for retrospective studies and for manuscripts submitted from countries in which English was the primary language. The prevalences of flaws in manuscripts were poor writing (62%), deficiencies in data (60%), logical or methodological errors (28%), content not suitable for Veterinary Radiology & Ultrasound (26%), and lack of new or useful knowledge (25%). Likelihood of manuscript rejection was greater for lack of new or useful knowledge and content not suitable than for other manuscript flaws. The lower acceptance rate for manuscripts from countries in which English was not the primary language was associated with content not suitable and not poor writing. Submitting authors are encouraged to do more to recognize and address manuscript flaws before submission, for example by internal review. Specifically, submitting authors should express clearly the potential added value of their study in the introduction section of their manuscript, describe completely their methods and results, and consult the Editor-in-Chief if they are uncertain whether their subject matter would be suitable for the journal. © 2014 American College of Veterinary Radiology.

Fertilizing properties of farm manure submitted to methane fermentation, according to pot tests

Energy Technology Data Exchange (ETDEWEB)

Kuzelewski, L; Pentkowski, A

1962-01-01

In order to compare the fertilizing properties of the ordinary farm manure stored and fermented in dung hills with those of the manure submitted to CH/sub 4/ fermentation, pot tests with oats and potatoes were carried out. Investigation showed that: N losses taking place during CH/sub 4/ fermentation are much smaller than those from manure fermented in dung-hills. Because of different fermentation processes, the losses of solid matter in the CH/sub 4/ fermentation were greater than in manure fermented and stored in dung-hills. Although the manure submitted to CH/sub 4/ fermentation contained more N, its effect on crops was almost identical with the effect of ordinary manure. Experiments have shown that it is not necessary to cover with soil the manure submitted to the CH/sub 4/ fermentation after spreading it. Whether it was covered with soil or not, there was no difference in crop yield. Manure fermenting in O-free atmosphere may contain products harmful to plants, but they oxidize quickly on exposure to the atmosphere. 53 references.

20 CFR 266.12 - Effect of matters or actions submitted or taken by legal guardian, etc.

Science.gov (United States)

2010-04-01

... taken by legal guardian, etc. 266.12 Section 266.12 Employees' Benefits RAILROAD RETIREMENT BOARD... submitted or taken by legal guardian, etc. All matters and actions in connection with an annuity submitted or taken by the guardian or other person legally vested with the care of the person or estate of an...

Financial analysis of diabetic patients hospitalizations submitted to lower limb amputation in a public hospital

Directory of Open Access Journals (Sweden)

Renata Santos Silva

2015-03-01

Full Text Available This study is a documental descriptive analysis which aimed to verify the cost established in 2006, in relation to the hospitalization of 21 diabetic patients submitted to the lower limb amputation in a public hospital and the value transferred by the Unified Health System (SUS regarding this procedure. Among the studied patients, 57.14% were female and 42.86% male, aged 40 to 90 years. The time of diagnosis varied from 5 to 25 years. The average of hospitalization was 14 days per patient. The cost to the hospital was R$ 99,455.74, average cost per patient was R$ 4,735.98. The total amount transferred by SUS to the hospital was R$ 27,740.15, a cost 3.6 times lower than the hospital costs. The SUS transferring is in accordance with the predetermined values for its table of procedure. Prevention is the only alternative to reduce the rate of amputation and improve survival of diabetes patients. It is necessary an early diagnosis and better control of diabetes mellitus with appropriate government and institutional policies.

30 CFR 210.204 - How do I submit facility data?

Science.gov (United States)

2010-07-01

... 210.204 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT FORMS AND REPORTS Production and Royalty Reports-Solid Minerals § 210.204 How do I submit facility... stockpile inventory. (3) You must include in your facility data all production processed in the facility...

Radiofrequency ablation of liver cancer: early evaluation of therapeutic response with contrast-enhanced ultrasonography

International Nuclear Information System (INIS)

Choi, Dong Gil; Lim, Hyo K.; Lee, Won Jae; Kim, Seung Hoon; Kim, Min Ju; Kim, Seung Kwon; Jang, Kyung Mi; Lee, Ji Yeon; Lim, Jae Hoon

2004-01-01

The early assessment of the therapeutic response after percutaneous radiofrequency (RF) ablation is important, in order to correctly decide whether further treatment is necessary. The residual unablated tumor is usually depicted on contrast-enhanced multiphase helical computed tomography (CT) as a focal enhancing structure during the arterial and portal venous phases. Contrast-enhanced color Doppler and power Doppler ultrasonography (US) have also been used to detect residual tumors. Contrast-enhanced gray-scale US, using a harmonic technology which has recently been introduced, allows for the detection of residual tumors after ablation, without any of the blooming or motion artifacts usually seen on contrast-enhanced color or power Doppler US. Based on our experience and reports in the literature, we consider that contrast-enhanced gray-scale harmonic US constitutes a reliable alternative to contrast-enhanced multiphase CT for the early evaluation of the therapeutic response to RF ablation for liver cancer. This technique was also useful in targeting any residual unablated tumors encountered during additional ablation

Evaluation of medial and lateral meniscus thicknesses in early osteoarthritis of the knee with magnetic resonance imaging

International Nuclear Information System (INIS)

Bamac, B.; Ozdemir, S.; Colak, T.; Ozbek, A.; Sarisoy, Hasan T.; Akansel, G.

2006-01-01

To evaluate early changes occurring in both medial and lateral meniscus thickness from the knees of patients with osteoarthritis (Oa). We conducted this study in the Department of Anatomy and Division of Radiology, Faculty of Medicine, Klucel University, Klucel, Turkey during the period 2004 to 2005. In this study, we measured the thickness of the medial and lateral meniscus in a group of 36 (50 knees) consecutive patients with chronic knee pain, and clinical findings of early Oa, and 10 (20 knees) control subjects using MRI. The thickness of the posterior horn of the medial meniscus and anterior horn of the lateral meniscus were significantly higher in the Oa patients compared with the control subjects. This study showed that meniscal degeneration in early stage Oa is not evenly distributed in the knee. Thickening of the menisci in some areas may occur due to their own localization and biomechanics. (author)

Plagiarism in submitted manuscripts: incidence, characteristics and optimization of screening-case study in a major specialty medical journal.

Science.gov (United States)

Higgins, Janet R; Lin, Feng-Chang; Evans, James P

2016-01-01

Plagiarism is common and threatens the integrity of the scientific literature. However, its detection is time consuming and difficult, presenting challenges to editors and publishers who are entrusted with ensuring the integrity of published literature. In this study, the extent of plagiarism in manuscripts submitted to a major specialty medical journal was documented. We manually curated submitted manuscripts and deemed an article contained plagiarism if one sentence had 80 % of the words copied from another published paper. Commercial plagiarism detection software was utilized and its use was optimized. In 400 consecutively submitted manuscripts, 17 % of submissions contained unacceptable levels of plagiarized material with 82 % of plagiarized manuscripts submitted from countries where English was not an official language. Using the most commonly employed commercial plagiarism detection software, sensitivity and specificity were studied with regard to the generated plagiarism score. The cutoff score maximizing both sensitivity and specificity was 15 % (sensitivity 84.8 % and specificity 80.5 %). Plagiarism was a common occurrence among manuscripts submitted for publication to a major American specialty medical journal and most manuscripts with plagiarized material were submitted from countries in which English was not an official language. The use of commercial plagiarism detection software can be optimized by selecting a cutoff score that reflects desired sensitivity and specificity.

78 FR 72139 - Forms Submitted to the Office of Management and Budget for Extension of Clearance

Science.gov (United States)

2013-12-02

... SELECTIVE SERVICE SYSTEM Forms Submitted to the Office of Management and Budget for Extension of Clearance AGENCY: Selective Service System. ACTION: Notice. The following forms have been submitted to the Office of Management and Budget (OMB) for extension of clearance in compliance with the Paperwork Reduction Act (44 U.S.C. Chapter 35): SSS FOR...

An Evaluation of Early Education Based on Physical Environmental Guidelines

Directory of Open Access Journals (Sweden)

Donna J. Satterlee

2015-05-01

Full Text Available The integration of environmental policies with political support for action on these policies is of prime significance for mobilization and progression of improving indoor environments. However, state licensing agencies and local county ordinances for child care centers do not universally follow these policies and standards. As a result, most early childhood educational programs operate without proper indoor environments. Indoor air quality, temperature, ventilation, daylighting, and acoustics are crucial factors for educational settings in early childhood education. This study documents the physical environment in early childhood education centers in three counties in Maryland. Results indicate that building performance and indoor air quality standards vary according to the socioeconomic status of children who attend early childhood programs, and environmental factors correlate with educational achievement (as measured by kindergarten readiness scores.

Family group interventions in an early psychosis program: A re-evaluation of practice after 10 years of service delivery.

Science.gov (United States)

Day, Kate; Starbuck, Rachael; Petrakis, Melissa

2017-08-01

The role of family in supporting service users in coping with illness and engaging in relapse prevention in early psychosis is important. Taking on this caring though is stressful and challenging, and it has been found that support and information for carers assists in their coping and reduces isolation. To evaluate the current utility of a psychoeducation group program in a public adult mental health service, for the families of people experiencing early psychosis. A purpose-designed pre- and post-intervention questionnaire was administered to quantitatively measure group participants' changes in perceptions of their understanding of mental illness and its treatment through attending the group. Additional qualitative items were used to determine other knowledge, benefits and any critical feedback. The group program continues to result in highly significant improvements in family members' understanding of psychosis, recovery, medications, relapse prevention and substance co-morbidities. Additional feedback reaffirmed previous findings that family members find group peer support valuable and that this reduces isolation and the experience of stigma. The current evaluation, conducted following 10 years of early psychosis group work, found there to be efficacy in family peer support groups and that it is important to provide family interventions in public early psychosis mental health services.

22 CFR 506.5 - Review and evaluation.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Review and evaluation. 506.5 Section 506.5 Foreign Relations BROADCASTING BOARD OF GOVERNORS PART-TIME CAREER EMPLOYMENT PROGRAM § 506.5 Review and evaluation. The part-time career employment program will be reviewed through semiannual reports submitted by...

Prevention and early intervention of anxiety problems in young children: A pilot evaluation of Cool Little Kids Online

Directory of Open Access Journals (Sweden)

Amy J. Morgan

2016-05-01

Full Text Available Anxiety disorders are common, debilitating, and begin early in life. Early intervention to prevent anxiety disorders in children who are at risk could have long-term impact. The ‘Cool Little Kids’ parenting group program has previously been shown to be efficacious in preventing anxiety disorders in temperamentally inhibited young children. Wider dissemination of the program could be achieved with an internet-based delivery platform, affording greater accessibility and convenience for parents. The aim of this study was to evaluate ‘Cool Little Kids Online’, a newly developed online version of the existing parenting group program. Fifty-one parents of children aged 3–6 years were recruited to evaluate the online program's acceptability and preliminary efficacy in reducing inhibited young children's anxiety problems. Parents were randomized to receive either a clinician-supported version or an unsupported version of the program. Parents had 10 weeks to access the program and completed questionnaires at baseline and post-intervention. Both groups showed medium-to-large reductions in children's anxiety symptoms, emotional symptoms, number of child anxiety diagnoses, and improvements in life interference from anxiety. The effect of clinician support was inconsistent and difficult to interpret. Parents reported high levels of satisfaction with the program. These encouraging results indicate that the online version is acceptable and useful for parents with temperamentally inhibited young children. Cool Little Kids Online may be a promising direction for improving access to an evidence-based prevention and early intervention program for child anxiety problems. A large randomized trial is warranted to further evaluate efficacy.

41 CFR 105-50.401 - Reports submitted to the Congress.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Reports submitted to the Congress. 105-50.401 Section 105-50.401 Public Contracts and Property Management Federal Property... Congress. (a) The Administrator of General Services will furnish annually to the respective Committees on...

13 CFR 108.2004 - Contents of application submitted by SSBICs.

Science.gov (United States)

2010-01-01

... the amount of Regulatory Capital it intends to raise after December 21, 2000, and the amount of... MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Requirements and Procedures for Operational Assistance Grants to... increase in its Regulatory Capital since December 21, 2000. (b) Plan. An SSBIC must submit a plan...

41 CFR 102-192.100 - How do we submit our annual mail management report to GSA?

Science.gov (United States)

2010-07-01

... management report to GSA? If your agency is a large agency, as defined in § 102-192.35, you must submit... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How do we submit our annual mail management report to GSA? 102-192.100 Section 102-192.100 Public Contracts and Property...

Evaluation of Elecsys Syphilis Assay for Routine and Blood Screening and Detection of Early Infection

OpenAIRE

Kremastinou, J.; Polymerou, V.; Lavranos, D.; Aranda Arrufat, A.; Harwood, J.; Mart?nez Lorenzo, M. J.; Ng, K. P.; Queiros, L.; Vereb, I.; Cusini, M.

2016-01-01

Treponema pallidum infections can have severe complications if not diagnosed and treated at an early stage. Screening and diagnosis of syphilis require assays with high specificity and sensitivity. The Elecsys Syphilis assay is an automated treponemal immunoassay for the detection of antibodies against T. pallidum. The performance of this assay was investigated previously in a multicenter study. The current study expands on that evaluation in a variety of diagnostic settings and patient popul...

Does ECG influence the conception rate Nelore cows presenting different body condition scores submitted to the same timed-AI protocol?

OpenAIRE

Erika Aline Ribeiro Dias; Rubens Paes de Arruda; Roni Aprecido Videschi; Hugo Borges Graff; Alessandra de Moraes Sousa; Fabio Morato Monteiro; Enilson Geraldo Ribeiro; Janaina Torres Carreira; Halim Atique Netto; Rogério Fonseca Guimarães Peres; Leticia Zoccolaro Oliveira

2013-01-01

The aim of this study was to evaluate the conception rate (CR) of multiparous Nelore cows presenting different body condition scores (BCS), which were submitted to the same Timed-AI protocol with equine chorionic gonadotrophin (eCG). A total of 1574 cows were inseminated, between 40 and 50 days postpartum. During insemination (timed-AI), all data regarding to bull (n=8), inseminator (n=3) and BCS (1 to 5) were recorded. The pregnancy diagnosis was performed, by ultrasonography, 40 days after ...

20 CFR 416.803 - Evaluation of evidence.

Science.gov (United States)

2010-04-01

..., BLIND, AND DISABLED Determination of Age § 416.803 Evaluation of evidence. Generally, the highest.... Among the documents which may be submitted for such purpose are: school record, census record, Bible or...

Evaluation of phototherapy in the differentiation of mesenchymal stem cells in the tissue repair of rats submitted to a hyperlipidemic diet

Science.gov (United States)

Oliveira, C. R. B.; Santos, L. S.; Silva, V. D. U.; Vitória, L. A.; Rodriguez, T. T.; Marques, A. M. C.; Xavier, F. C. A.; Ramalho, L.

2018-04-01

Obese people present a greater risk of developing other systemic diseases and comorbidities such as compromising the tissue repair process. Laser phototherapy can contribute to this repair by improving cellular functions, since stem cells may play an important role in repair due to their pluripotent potential. In this way, the influence of Laser Phototherapy (LP) was evaluated in the tissue repair of rats submitted to a hyperlipid diet through CD49 immunostaining for adipose stem cells. Forty-eight Wistar albinus rats were divided into two experimental groups: Standard Diet (SD) and Hyperlipid Diet (HD) for 20 weeks. After this period, excisional dorsal cutaneous wounds of 1 cm2 were made. The groups were subdivided into control and laser, the laser groups were irradiated (Diode Laser of Gallium and Aluminum Arsenide, λ660nm, 40mW, 6J / cm2) immediately after the surgery and every 48 hours. A group of rats were killed on day 7 and the other group on day 14 and the specimens processed by the immunohistochemical technique. The SD group presented antibodies marked with moderate to intense intensity, whereas in the HD group the weak staining for the time of 14 days prevailed. The irradiation protocol employed had no influence on the CD49 marker when compared to the control and irradiated groups over the same period. According to the methodology used and the results obtained it is concluded that laser light does not influence the recruitment of adipoderivative stem cells for the tissue repair process.

48 CFR 652.219-73 - Mentor Requirements and Evaluation.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Mentor Requirements and... Mentor Requirements and Evaluation. As prescribed in 619.202-70(o)(2), insert the following clause: Mentor Requirements and Evaluation (APR 2004) (a) Mentor and protégé firms shall submit an evaluation to...

48 CFR 1052.219-75 - Mentor Requirements and Evaluation.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Mentor Requirements and... Mentor Requirements and Evaluation. As prescribed in DTAR 1019.202-70, insert the following clause: Mentor Requirements and Evaluation (JAN 2000) (a) Mentor and protégé firms shall submit an evaluation to...

Alterations in the hypothalamic–pituitary–thyroid axis in animals submitted to early-life trauma

Directory of Open Access Journals (Sweden)

Tania Diniz Machado

2017-09-01

Full Text Available Introduction: Changes in maternal care can affect offspring’s thyroid hormone T3 levels. Pups from highly caring mothers have higher levels of thyroid hormone T3. In humans, physical abuse in childhood is related to lower levels of T3 in adolescence. This study aimed at verifying if early-life trauma in rodents is correlated with T3 levels in adulthood. Methods: From the second day of life, litters of Wistar rats were subjected to reduced nesting material (Early–Life Stress-ELS or standard care (Controls. In adult life, the animals were chronically exposed to standard diet or standard diet + palatable diet and plasma T3 levels were measured before and after the exposition to diet. Results: Thyroid hormone T3 levels in adult life correlated negatively with the licking and grooming (LG scores in the ELS group. This correlation disappeared when the animals had the opportunity to choose between two diets chronically. Conclusion: The adverse environment affected maternal behavior and caused marks on the metabolism of the intervention group (T3, which were reverted by chronic palatable food consumption. Keywords: Trauma; T3; stress

Radiation dose evaluation in patients submitted to conventional radiological examinations

International Nuclear Information System (INIS)

Tilly Junior, Joao G.

1997-01-01

This work presents the results of the evaluation of radiation dose delivered to the patients undergoing conventional radiological procedures. Based in the realized measurement some indicators are settled to quantitative appraisal of the radiological protection conditions offered to the population. Data assessment was done in the county of Curitiba, in Parana State, Brazil, from 12/95 to 04/96, in ten rooms of three different institutions, under 101 patients, adults with 70 ± 10 kg, during real examinations of chest PA, chest LAT and abdomen AP. (author)

Chromium Toxicity Test for Fall Chinook Salmon (Oncorhynchus tshawytscha) Using Hanford Site Groundwater: Onsite Early Life-Stage Toxicity Evaluation

International Nuclear Information System (INIS)

Patton, Gregory W; Dauble, Dennis D; Chamness, Mickie A; Abernethy, Cary S; McKinstry, Craig A

2001-01-01

The objective of this study was to evaluate site-specific effects for early life-stage (eyed eggs to free swimming juveniles) fall chinook salmon that might be exposed to hexavalent chromium from Hanford groundwater sources. Our exposure conditions included hexavalent chromium obtained from Hanford groundwater wells near the Columbia River, Columbia River water as the diluent, and locally adapted populations of fall chinook salmon. This report describes both a 96-hr pretest using rainbow trout eggs and an early life-stage test beginning with chinook salmon eggs

Item-Level and Construct Evaluation of Early Numeracy Curriculum-Based Measures

Science.gov (United States)

Lee, Young-Sun; Lembke, Erica; Moore, Douglas; Ginsburg, Herbert P.; Pappas, Sandra

2012-01-01

The present study examined the technical adequacy of curriculum-based measures (CBMs) of early numeracy. Six 1-min early mathematics tasks were administered to 137 kindergarten and first-grade students, along with an omnibus test of early mathematics. The CBM measures included Count Out Loud, Quantity Discrimination, Number Identification, Missing…

30 CFR 210.202 - How do I submit sales summaries?

Science.gov (United States)

2010-07-01

... documents from your own records. You do not need to re-format them before submitting them to us: Data... washing costs Monthly Monthly Not Required Monthly Monthly Not Required (v) Transportation costs Monthly... Management, Solid Minerals and Geothermal Compliance and Asset Management, P.O. Box 25165, MS 390G1, Denver...

13 CFR 108.2005 - Contents of plan submitted by SSBICs.

Science.gov (United States)

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Contents of plan submitted by... Operational Assistance. The SSBIC must describe how it plans to use its grant funds to provide Operational... types of Operational Assistance it proposes to provide, and how it plans to provide the Operational...

Evaluation of rheological behavior and sensory properties of ready to eat salad dressings submitted to irradiation; Avaliacao do comportamento reologico e das propriedades sensoriais de molhos comerciais para salada tratados por irradiacao

Energy Technology Data Exchange (ETDEWEB)

Gallo, Juliana Maria Altavista Sagretti

2013-08-01

This study evaluated the rheological behavior of 11 salad dressings ready to eat, processed by gamma irradiation, at doses: 3 kGy and 5 kGy. This assessment was made by rheograms traced by measurements of viscosity and shear stress by shear rate. Mathematical parameters obtained from these measures also contributed to the conclusion of the behavior exhibited and for choosing the best mathematical model applicable to them. The measurements were performed on a Brookfield viscometer Model LVDV - III. The Neslab thermal bath was used to maintain ambient temperature during the whole analysis. This study protocol was done in two stages. In step 1, the evaluation was performed soon after the samples have been irradiated when these were close to their dates of manufacture. In phase 2 the samples were reassessed after a period of storage, near the expiration date of their validity. Simultaneously pH measurement was performed to evaluate their stability in the face of treatment and sensory analyzes of two salad dressings were studied, in order to verify the acceptance of these when submitted to irradiation. The shear-thinning behavior was confirmed for all dressings through the mathematical model, the power law, that best model apply to this, in both phases. The irradiation at the absorbed doses studied did not influence this behavior. The results of sensory evaluation indicated good acceptance of irradiated sauces for the tasters. (author)

Evaluating Indicators and Life Cycle Inventories for Processes in Early Stages of Technical Readiness

Energy Technology Data Exchange (ETDEWEB)

Tan, Eric C [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Smith, Raymond [U.S. Environmental Protection Agency (EPA); Ruiz-Mercado, Gerardo [U.S. Environmental Protection Agency (EPA)

2017-11-01

This presentation examines different methods for analyzing manufacturing processes in the early stages of technical readiness. Before developers know much detail about their processes, it is valuable to apply various assessments to evaluate their performance. One type of assessment evaluates performance indicators to describe how closely processes approach desirable objectives. Another type of assessment determines the life cycle inventories (LCI) of inputs and outputs for processes, where for a functional unit of product, the user evaluates the resources used and the releases to the environment. These results can be compared to similar processes or combined with the LCI of other processes to examine up-and down-stream chemicals. The inventory also provides a listing of the up-stream chemicals, which permits study of the whole life cycle. Performance indicators are evaluated in this presentation with the U.S. Environmental Protection Agency's GREENSCOPE (Gauging Reaction Effectiveness for ENvironmental Sustainability with a multi-Objective Process Evaluator) methodology, which evaluates processes in four areas: Environment, Energy, Economics, and Efficiency. The method develops relative scores for indicators that allow comparisons across various technologies. In this contribution, two conversion pathways for producing cellulosic ethanol from biomass, via thermochemical and biochemical routes, are studied. The information developed from the indicators and LCI can be used to inform the process design and the potential life cycle effects of up- and down-stream chemicals.

Quality of Impressions and Work Authorizations Submitted by Dental Students Supervised by Prosthodontists and General Dentists.

Science.gov (United States)

Imbery, Terence A; Diaz, Nicholas; Greenfield, Kristy; Janus, Charles; Best, Al M

2016-10-01

Preclinical fixed prosthodontics is taught by Department of Prosthodontics faculty members at Virginia Commonwealth University School of Dentistry; however, 86% of all clinical cases in academic year 2012 were staffed by faculty members from the Department of General Practice. The aims of this retrospective study were to quantify the quality of impressions, accuracy of laboratory work authorizations, and most common errors and to determine if there were differences between the rate of errors in cases supervised by the prosthodontists and the general dentists. A total of 346 Fixed Prosthodontic Laboratory Tracking Sheets for the 2012 academic year were reviewed. The results showed that, overall, 73% of submitted impressions were acceptable at initial evaluation, 16% had to be poured first and re-evaluated for quality prior to pindexing, 7% had multiple impressions submitted for transfer dies, and 4% were rejected for poor quality. There were higher acceptance rates for impressions and work authorizations for cases staffed by prosthodontists than by general dentists, but the differences were not statistically significant (p=0.0584 and p=0.0666, respectively). Regarding the work authorizations, 43% overall did not provide sufficient information or had technical errors that delayed prosthesis fabrication. The most common errors were incorrect mountings, absence of solid casts, inadequate description of margins for porcelain fused to metal crowns, inaccurate die trimming, and margin marking. The percentages of errors in cases supervised by general dentists and prosthodontists were similar for 17 of the 18 types of errors identified; only for margin description was the percentage of errors statistically significantly higher for general dentist-supervised than prosthodontist-supervised cases. These results highlighted the ongoing need for faculty development and calibration to ensure students receive the highest quality education from all faculty members teaching fixed

Experimental test on aluminium rod submitted to a laminar water flow

International Nuclear Information System (INIS)

Britto Aghina, L.O. de; Cruz, J.R.B.

1986-06-01

The result obtained from a experiment with an aluminium rod submitted to a laminar water flow is compared to the result predicted by empirical correlations used in the vibration analysis of the RPR reactor fuel rods. (L.C.J.A.)

Radiological Evaluation of Strategic Structures in Patients with Mild Cognitive Impairment and Early Alzheimer’s Disease

International Nuclear Information System (INIS)

Nesteruk, Tomasz; Nesteruk, Marta; Styczyńska, Maria; Barcikowska-Kotowicz, Maria; Walecki, Jerzy

2016-01-01

The aim of the study was to evaluate the diagnostic value of two measurement techniques in patients with cognitive impairment – automated volumetry of the hippocampus, entorhinal cortex, parahippocampal gyrus, posterior cingulate gyrus, cortex of the temporal lobes and corpus callosum, and fractional anisotropy (FA) index measurement of the corpus callosum using diffusion tensor imaging. A total number of 96 patients underwent magnetic resonance imaging study of the brain – 33 healthy controls (HC), 33 patients with diagnosed mild cognitive impairment (MCI) and 30 patients with Alzheimer’s disease (AD) in early stage. The severity of the dementia was evaluated with neuropsychological test battery. The volumetric measurements were performed automatically using FreeSurfer imaging software. The measurements of FA index were performed manually using ROI (region of interest) tool. The volumetric measurement of the temporal lobe cortex had the highest correct classification rate (68.7%), whereas the lowest was achieved with FA index measurement of the corpus callosum (51%). The highest sensitivity and specificity in discriminating between the patients with MCI vs. early AD was achieved with the volumetric measurement of the corpus callosum – the values were 73% and 71%, respectively, and the correct classification rate was 72%. The highest sensitivity and specificity in discriminating between HC and the patients with early AD was achieved with the volumetric measurement of the entorhinal cortex – the values were 94% and 100%, respectively, and the correct classification rate was 97%. The highest sensitivity and specificity in discriminating between HC and the patients with MCI was achieved with the volumetric measurement of the temporal lobe cortex – the values were 90% and 93%, respectively, and the correct classification rate was 92%. The diagnostic value varied depending on the measurement technique. The volumetric measurement of the atrophy proved to be

Radiation induced early delayed changes in mice brain: a 1h MRS and behavioral evaluation study

International Nuclear Information System (INIS)

Gupta, Mamta; Rana, Poonam; Haridas, Seenu; Manda, Kailash; Hemanth Kumar, B.S.; Khushu, Subash

2014-01-01

Radiation induced CNS injury can be classified as acute, early delayed and late delayed. Most of the studies suggest that acute injury is reversible whereas early delayed and late delayed injury is irreversible leading to metabolic and cognitive impairment. Extensive research has been carried out on cranial radiation induced early and late delayed changes, there are no reports on whole body radiation induced early and delayed changes. The present study was designed to observe early delayed effects of radiation during whole body radiation exposure. A total of 20 C57 male mice were divided in two groups of 10 animals each. One group was exposed to a dose of 5 Gy whole body radiation through Tele 60 Co irradiation facility with source operating at 2.496 Gy/min, while other group served as sham irradiated control. Behavioral and MR spectroscopy was carried out 3 months post irradiation. Behavioral parameters such as locomotor activity and working memory were evaluated first then followed by MR spectroscopy at 7T animal MRI system. For MRS, voxel was localised in the cortex-hippocampus region of mouse brain. MR spectra were acquired using PRESS sequence, FID was processed using LC model for quantitation. The data showed impaired cognitive functions and altered metabolite levels during early delayed phase of whole body radiation induced injury. In behavioural experiments, there was a significant impairment in the cognitive as well as exploratory functions at 3 months post irradiation in irradiated group as compared to controls. MRS results explained changes in mI, glutamine and glx levels in irradiated animals compared to controls. Altered mI level has been found to be associated with reduced cognitive abilities in many brain disorders including MCI and Alzheimer's disease. The findings of this study suggest that whole body radiation exposure may have long lasting effect on the cognitive performance. (author)

Behaviour of a reactor PWR containment submitted to an external explosion

International Nuclear Information System (INIS)

Barbe, B.; Avet-Flancard, R.; Perrot, J.; Berriaud, C.; Dulac, J.

1981-01-01

The aims of this study are to obtain experimental data and theoretical evaluation of the transient field pressure existing on importants buildings of the plant. The knowledge of the pressure loading permits then to predict the structure mechanical behaviour. For this purpose the cylindrical reactor building and the parallelepipedic fuel building have been modelized to a 1/40 scale. These models were realized as carefully as possible with prestressing in the thickness of microconcrete walls and were submitted to incident shock waves obtained by T.N.T. explosions. Several characteristics explosion directions have been tested. Experimental data were recorded with pressure and displacement transducers and also by accelerometers. The results show that: 1) the geometrical dihedral between reactor and fuel building induces local overpressures five times the incident pressures; 2) no apparent damage occurred on the structure, for the range of field pressure tested so far; this may related to only small effects of resonances. Simultaneously a tridimensional, acoustic code has been developed an conveniently correlates experimental data. (orig./HP)

Prediction and evaluation method of wind environment in the early design stage using BIM-based CFD simulation

International Nuclear Information System (INIS)

Lee, Sumi; Song, Doosam

2010-01-01

Drastic urbanization and manhattanization are causing various problems in wind environment. This study suggests a CFD simulation method to evaluate wind environment in the early design stage of high-rise buildings. The CFD simulation of this study is not a traditional in-depth simulation, but a method to immediately evaluate wind environment for each design alternative and provide guidelines for design modification. Thus, the CFD simulation of this study to evaluate wind environments uses BIM-based CFD tools to utilize building models in the design stage. This study examined previous criteria to evaluate wind environment for pedestrians around buildings and selected evaluation criteria applicable to the CFD simulation method of this study. Furthermore, proper mesh generation method and CPU time were reviewed to find a meaningful CFD simulation result for determining optimal design alternative from the perspective of wind environment in the design stage. In addition, this study is to suggest a wind environment evaluation method through a BIM-based CFD simulation.

30 CFR 285.905 - When must I submit my decommissioning application?

Science.gov (United States)

2010-07-01

... application? 285.905 Section 285.905 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Decommissioning Decommissioning Applications § 285.905 When must I submit my decommissioning application? You must...

Mid-term evaluation of the Climate Change Action Fund: Technology Early Action Measures (TEAM) block

International Nuclear Information System (INIS)

2001-11-01

To assist Canada in meeting its commitments under the Kyoto Protocol for the reduction of greenhouse gas emissions, the Government of Canada established the Climate Change Action Fund (CCAF) in 1998. Under the CCAF umbrella, the Technology Early Action Measures (TEAM) Block was initially allocated 60 million dollars over a three-year period for the provision of cost-shared support to speed up the development and deployment of cost-effective near market-ready greenhouse gases emission reducing technologies. The main avenues adopted by TEAM in its mandate were: supporting technology development and deployment, overcoming obstacles to technology development and deployment, and piloting technology transfer to developing countries and countries in transition. A mid-term evaluation of its performance to date was conducted. It proved to be too early for an adequate assessment of the extent to which the projects sponsored by TEAM demonstrated technical success in reducing greenhouse gases emissions, considering the time-consuming tasks required for the development and negotiation of technology projects. Most projects to date have not moved beyond the early stages benchmark. It was determined that the expected outcomes will be achieved. The innovative approach selected by TEAM, building on existing programs, appeared to be very effective. Findings and recommendations were discussed in this report

18 CFR 35.5 - Rejection of material submitted for filing.

Science.gov (United States)

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Rejection of material submitted for filing. 35.5 Section 35.5 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... that fails to comply with this Part may be rejected by the Director of the Office of Energy Market...

Citation analysis of doctoral theses submitted to the department of ...

African Journals Online (AJOL)

This is a bibliometric study carried out on eighty doctoral theses submitted to the Department of Library, Archival and Information Studies at the University of Ibadan, with the aim of determining the characteristics of citations in the theses. Most of the citations were to journals and books. Majority of the sources cited were old.

Performance of calves submitted to protocols using extruded or ground starter

Directory of Open Access Journals (Sweden)

Amália Saturnino Chaves

2014-10-01

Full Text Available Feed processing can affect rumen development in new born calves, and potentially define animal performance. Two feed management systems, extruded starter (Ruter with possible early weaning and ground starter (control, were evaluated in thirty-two Holstein calves (16 females and 16 males. Animals were randomly assigned to the treatments using a randomized block design with birth weight as a covariate. They were weaned when starter intake reached 800 g for two consecutive days. Twenty-one days after the weaning, males were slaughtered and the stomach compartments were isolated. Rumen and omasum fragments were processed for morphological evaluation. Animal performance, clinical condition and stomach compartment weight did not differ between the treatments (P> 0.05, despite weaning weight of animals receiving extruded starter being 5.68% higher than the control animals. Extruded starter stimulated cell proliferation of the ruminal epithelium (P <0.05, but did not affect the dimensions of the papillary rumen and omasum mitotic index (MI. The Ruter feeding system was potentially beneficial for weight gain and morphofunctional rumen development in lactating animals; however, this treatment did not allow early weaning as proposed by the feeding system.

Developing an inventor support service which performs early stage market and manufacturing evaluations. Final report

Energy Technology Data Exchange (ETDEWEB)

1991-10-01

American businesses are learning the difficult high cost lesson of ignoring production and market factors (producibility, unit product cost (UPC), marketability, etc) during the engineering design phase of product development. Studies have shown that the Japanese spend three times as long as Americans in the design feasibility and decision process of new product introductions and one third the amount of time in the implementation of those products. There is a 20 to 1 cost benefit on effort applied in the design phase versus the production phase of the product life cycle. The number one goal of this project was to establish an organization that has, as one of its purposes, the providing of services responsive to the needs of independent inventors. The number two goal was to demonstrate the value of providing marketing and manufacturing counsel at an early stage in the product development process. The first study goal was met by providing the materials and information necessary to establish an evaluation team and an organization to handle such evaluations. The second study goal was met by demonstrating the impact of early market analysis and manufacturing considerations on product design and therefore on the description of the invention for four different inventions. These inventions were selected at various stages of development. Regardless of stage of development, the marketing and manufacturing reviews resulted in significant changes in design and/or market positioning.

Developing an inventor support service which performs early stage market and manufacturing evaluations. [Final Report

Energy Technology Data Exchange (ETDEWEB)

1991-10-01

American businesses are learning the difficult high cost lesson of ignoring production and market factors (producibility, unit product cost (UPC), marketability, etc) during the engineering design phase of product development. Studies have shown that the Japanese spend three times as long as Americans in the design feasibility and decision process of new product introductions and one third the amount of time in the implementation of those products. There is a 20 to 1 cost benefit on effort applied in the design phase versus the production phase of the product life cycle. The number one goal of this project was to establish an organization that has, as one of its purposes, the providing of services responsive to the needs of independent inventors. The number two goal was to demonstrate the value of providing marketing and manufacturing counsel at an early stage in the product development process. The first study goal was met by providing the materials and information necessary to establish an evaluation team and an organization to handle such evaluations. The second study goal was met by demonstrating the impact of early market analysis and manufacturing considerations on product design and therefore on the description of the invention for four different inventions. These inventions were selected at various stages of development. Regardless of stage of development, the marketing and manufacturing reviews resulted in significant changes in design and/or market positioning.

Trends in the number and the quality of trial protocols involving children submitted to a French Institutional Review Board

Directory of Open Access Journals (Sweden)

Isabelle Gautier

2017-08-01

Full Text Available Abstract Background There is a great need for high quality clinical research for children. The European Pediatric Regulation aimed to improve the quality of clinical trials in order to increase the availability of treatments for children. The main purpose of this study was to assess the evolution of both the number and the quality of pediatric trial protocols that were submitted to a French Institutional Review Board (IRB00009118 before and after the initiation of the EU Pediatric Regulation. Methods All protocols submitted to the IRB00009118 between 2003 and 2014 and conducting research on subjects under eighteen years of age were eligible. The quality of randomized clinical trials was assessed according to the guidelines developed by the Enhancing the QUAlity and Transparency Of health Research (EQUATOR Network and ranked using the Jadad score. Results Out of 622 protocols submitted to the Institutional Review Board (IRB, 21% (133/622 included children. Among these 133 pediatric protocols, the number of submitted pediatric protocols doubled between the two studied periods. From 2003 to 2008, 47 protocols including 21 institutionally sponsored were submitted to the IRB and from 2009 until 2014, 86 protocols including 48 institutionally sponsored were submitted. No significant trend was observed on the quality of RCTs. The overall median score of RCTs on the Jadad scale was high (3.5, 70.0% of protocols had a Jadad score ≥ 3, and 30.0% had a score < 3. Conclusion Following the EU Pediatric Regulation, the number of pediatric protocols submitted to the IRB00009118 tends to increase, but no change was noticed regarding their quality.

[Evaluation of risk factors of falls in early postmenopausal women].

Science.gov (United States)

Nahas, Eliana Aguiar Petri; Omodei, Michelle Sako; Cangussu, Luciana Mendes; Nahas-Neto, Jorge

2013-11-01

It was to evaluate the frequency and the risk factors of falls in early postmenopausal women. A cross-sectional study was conducted on 358 women (age: 45-65 years and amenorrhea >12 months) with time since menopause fall was identified as an unexpected unintentional change in position which causes an individual to remain in a lower level in relation to the initial position. The history of self-reported falls during the previous 24 months, and clinical and anthropometric data (body mass index (BMI) and waist circumference (WC)) and bone densitometric measures were analyzed. For statistical analysis, c² trend test and the logistic regression method (odds ratio (OR)) were used for the comparison between groups of women with and without falls. Of the 358 women, 48.0% (172/358) had a history of falls and 17.4% (30/172) had fractures. The fall occurred indoors (at home) in 58.7% (101/172). The mean age was 53.7 ± 6.5 years, time since menopause 5.8 ± 3.5 years, BMI 28.3 ± 4.6 kg/m² and WC 89.0 ± 11.4 cm. There were differences as the occurrence of smoking and diabetes, with greater frequency among fallers vs. non-fallers, 25.6 versus 16.1% and 12.8 versus 5.9%, respectively (prisk of falls in the presence of influential variables, it was observed that risk increased with current smoking status (OR 1.93; 95%CI 1.01-3.71), whereas other clinical and anthropometric variables did not influence this risk. In early postmenopausal women there was higher frequency of falls. Current smoking was clinical indicators of risk for falls. With the recognition of factors for falling, preventive measures become important, as the orientation of abolishing smoking.

Survivors of early childhood trauma: evaluating a two-dimensional diagnostic model of the impact of trauma and neglect

Directory of Open Access Journals (Sweden)

Marleen Wildschut

2014-04-01

Full Text Available Background: A two-dimensional diagnostic model for (complex trauma-related and personality disorders has been proposed to assess the severity and prognosis of the impact of early childhood trauma and emotional neglect. An important question that awaits empirical examination is whether a distinction between trauma-related disorders and personality disorders reflects reality when focusing on survivors of early childhood trauma. And, is a continuum of trauma diagnoses a correct assumption and, if yes, what does it look like? Objective: We describe the design of a cross-sectional cohort study evaluating this two-dimensional model of the impact of trauma and neglect. To provide the rationale of our study objectives, we review the existing literature on the impact of early childhood trauma and neglect on trauma-related disorders and personality disorders. Aims of the study are to: (1 quantify the two-dimensional model and test the relation with trauma and neglect; and (2 compare the two study groups. Method: A total of 200 consecutive patients referred to two specific treatment programs (100 from a personality disorder program and 100 from a trauma-related disorder program in the north of Holland will be included. Data are collected at the start of treatment. The assessments include all DSM-5 trauma-related and personality disorders, and general psychiatric symptoms, trauma history, and perceived emotional neglect. Discussion: The results will provide an evaluation of the model and an improvement of the understanding of the relationship between trauma-related disorders and personality disorders and early childhood trauma and emotional neglect. This may improve both diagnostic as well as indication procedures. We will discuss possible strengths and limitations of the design.

Wear resistance of AISI 304 stainless steel submitted to low temperature plasma carburizing

Directory of Open Access Journals (Sweden)

Marcos Antônio Barcelos

Full Text Available Abstract Despite the AISI 304 stainless steel has high corrosion/oxidation resistance, its tribological properties are poor, being one of the barriers for use in severe wear applications. Thus, there is a wide field for studying technologies that aim to increase the surface hardness and wear resistance of this material. In this work, hardness and wear resistance for AISI 304 stainless steel submitted to the thermochemical treatment by low temperature plasma carburizing (LTPC in a fixed gas mixture composition of 93% H2 and 7% CH4 are presented. Through the evaluation of the carburizing layers, it was possible to observe a substantial improvement in tribological properties after all temperature and time of treatment. This improvement is directly related to the increase of the process variables; among them temperature has a stronger influence on the wear resistance obtained using LTPC process.

Evaluation of F8-TNF-α in Models of Early and Progressive Metastatic Osteosarcoma

Directory of Open Access Journals (Sweden)

Bernhard Robl

2017-06-01

Full Text Available The targeted delivery of tumor necrosis factor-α (TNF-α with antibodies specific to splice isoforms of fibronectin [e.g., F8-TNF, specific to the extra-domain A (EDA domain of fibronectin] has already shown efficacy against experimental sarcomas but has not yet been investigated in orthotopic sarcomas. Here, we investigated F8-TNF in a syngeneic K7 M2–derived orthotopic model of osteosarcoma as a treatment against pulmonary metastases, the most frequent cause of osteosarcoma-related death. Immunofluorescence on human osteosarcoma tissue confirmed the presence of EDA in primary tumors (PTs as well as metastases. In mice, the efficacy of F8-TNF against PTs and early pulmonary metastases was evaluated. Intratibial PT growth was not affected by F8-TNF, yet early micrometastases were reduced possibly due to an F8-TNF–dependent attraction of pulmonary CD4+, CD8+, and natural killer cells. Furthermore, immunofluorescence revealed stronger expression of EDA in early pulmonary metastases compared with PT tissue. To study progressing pulmonary metastases, a hind limb amputation model was established, and the efficacy of F8-TNF, alone or combined with doxorubicin, was investigated. Despite the presence of EDA in metastases, no inhibition of progressive metastatic growth was detected. No significant differences in numbers of CD4+ or CD8+ cells or F4/80+ and Ly6G+ myeloid-derived cells were observed, although a strong association between metastatic growth and presence of pulmonary Ly6G+ myeloid-derived cells was detected. In summary, these findings demonstrate the potential of F8-TNF in activating the immune system and reducing early metastatic growth yet suggest a lack of efficacy of F8-TNF alone or combined with doxorubicin against progressing osteosarcoma metastases.

Evaluation of F8-TNF-α in Models of Early and Progressive Metastatic Osteosarcoma.

Science.gov (United States)

Robl, Bernhard; Botter, Sander Martijn; Boro, Aleksandar; Meier, Daniela; Neri, Dario; Fuchs, Bruno

2017-06-01

The targeted delivery of tumor necrosis factor-α (TNF-α) with antibodies specific to splice isoforms of fibronectin [e.g., F8-TNF, specific to the extra-domain A (EDA) domain of fibronectin] has already shown efficacy against experimental sarcomas but has not yet been investigated in orthotopic sarcomas. Here, we investigated F8-TNF in a syngeneic K7 M2-derived orthotopic model of osteosarcoma as a treatment against pulmonary metastases, the most frequent cause of osteosarcoma-related death. Immunofluorescence on human osteosarcoma tissue confirmed the presence of EDA in primary tumors (PTs) as well as metastases. In mice, the efficacy of F8-TNF against PTs and early pulmonary metastases was evaluated. Intratibial PT growth was not affected by F8-TNF, yet early micrometastases were reduced possibly due to an F8-TNF-dependent attraction of pulmonary CD4 + , CD8 + , and natural killer cells. Furthermore, immunofluorescence revealed stronger expression of EDA in early pulmonary metastases compared with PT tissue. To study progressing pulmonary metastases, a hind limb amputation model was established, and the efficacy of F8-TNF, alone or combined with doxorubicin, was investigated. Despite the presence of EDA in metastases, no inhibition of progressive metastatic growth was detected. No significant differences in numbers of CD4 + or CD8 + cells or F4/80 + and Ly6G + myeloid-derived cells were observed, although a strong association between metastatic growth and presence of pulmonary Ly6G + myeloid-derived cells was detected. In summary, these findings demonstrate the potential of F8-TNF in activating the immune system and reducing early metastatic growth yet suggest a lack of efficacy of F8-TNF alone or combined with doxorubicin against progressing osteosarcoma metastases. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

30 CFR 285.611 - What information must I submit with my SAP to assist MMS in complying with NEPA and other...

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What information must I submit with my SAP to... Assessment Plan § 285.611 What information must I submit with my SAP to assist MMS in complying with NEPA and other relevant laws? (a) You must submit with your SAP detailed information to assist MMS in complying...

40 CFR 8.8 - Comprehensive environmental evaluation.

Science.gov (United States)

2010-07-01

... conduct of scientific research and on other existing uses and values; (10) An identification of gaps in... evaluation. (a) Preparation of a CEE. Unless a PERM or an IEE has been submitted and determined to meet the... evaluate the CEE to determine if the CEE meets the requirements under Article 8 and Annex I to the Protocol...

Dual influences of early-life maternal deprivation on histone deacetylase activity and recognition memory in rats.

Science.gov (United States)

Albuquerque Filho, Manoel Osório; de Freitas, Betânia Souza; Garcia, Rebeca Carvalho Lacerda; Crivelaro, Pedro Castilhos de Freitas; Schröder, Nadja; de Lima, Maria Noêmia Martins

2017-03-06

Exposure to stress early in life may negatively impact nervous system functioning, including increasing the proneness to learning and memory impairments later in life. Maternal deprivation, a model of early-life stress, hinders memory in adult rats and lessens brain-derived neurotrophic factor (BDNF) levels in the hippocampus in a very heterogeneous way among individuals. The main goal of the present study was to investigate the possible epigenetic modulation underlying recognition memory impairment and reduced BDNF levels in the hippocampus of adult maternally deprived rats. We also evaluated the potential ameliorating properties of the histone deacetylase (HDAC) inhibitor, sodium butyrate, on memory deficits and BDNF changes related to maternal deprivation. Maternally deprived animals were categorized as 'inferior learners' and 'superior learners' according to their performance in object recognition memory task in comparison to controls. Results indicated that HDAC activity was higher in individuals submitted to maternal deprivation with the worst cognitive performance (inferior learners). Acute administration of sodium butyrate increased histone H3 acetylation and BDNF levels, and restored recognition memory in maternally deprived animals with the worst cognitive performance. Moreover, we also showed that there is a positive correlation between BDNF levels and memory performance. Taken together, the results indicated that HDAC inhibitors could be considered as a possible therapeutic agent to improve cognitive performance in inferior learners. Further studies need to be conducted for a better comprehension of the mechanisms related to persistent alterations observed in adult life induced by early stressful circumstances and those leading to resilience. Copyright © 2017 IBRO. Published by Elsevier Ltd. All rights reserved.

PHYSICAL-CHEMICAL QUALITY OF MANGO ‘Ubá’ (Mangifera indica L. FRUITS SUBMITTED TO IMPACT MECHANICAL DAMAGE AT HARVEST

Directory of Open Access Journals (Sweden)

ANÁLIA LÚCIA VIEIRA PACHECO

Full Text Available ABSTRACT The objective of this study was to evaluate the quality of ‘Ubá’ mango fruit submitted to mechanical damage. The fruits were harvested in the 2012/2013 harvest, and let to drop once on a flat, hard surface, simulating the harvesting process of ‘Ubá’ mango, which is to drop all the fruits of a plant when they are physiologically mature. Treatments consisted of different drop heights (zero, one, two, three, four and five meters, totaling six treatments. After the fall, the fruits were submitted to ripening, and then evaluated for fresh mass loss (FML, presence of external lesions (PEL, presence of internal lesions (PIL, soluble solids content (SS,titratable acidity (TA, pH, SS/TA ratio and vitamin C. There was no difference between fresh weight loss of the dropped fruits and control. Regarding the presence of external and internal lesions, damage in fruits due to drop height tends to increase. The fruits that were not dropped presented higher SS content than the others, while those that fell from a height of 5 m had the vitamin C content reduced by 27.78% compared to control. The decrease in SS content and vitamin C was influenced by damage caused by the impact. It is concluded that mechanical damage caused by the impact interferes in the main attributes of quality of fruits and pulp of “Ubá” mango.

Toward an African-Christian Demonology: The Demonologies of African Traditional Religion, African Christianity, and Early Christianity in Dialogue

Directory of Open Access Journals (Sweden)

Moscicke, Hans

2017-11-01

Full Text Available Christian interactions with the spirit-world of African traditional religion (ATR have remained problematic due, in part, to the failure of Christian missionaries to understand in detail the cosmology of ATR and the angelologies and demonologies of early Christianity. In this article I suggest a way beyond this impasse. I first survey the shape of cosmology and demonology in ATR, and then examine African Christianitys variegated responses to these traditional beliefs. Finally, I submit that a retrieval of the early Christian mythological narrative about demons and its associated cosmology could help theologians accommodate the spirit-world of ATR within a truly African-Christian theology.

Early life seizures in female rats lead to anxiety-related behavior and abnormal social behavior characterized by reduced motivation to novelty and deficit in social discrimination.

Science.gov (United States)

Castelhano, Adelisandra Silva Santos; Ramos, Fabiane Ochai; Scorza, Fulvio Alexandre; Cysneiros, Roberta Monterazzo

2015-03-01

Previously, we demonstrated that male Wistar rats submitted to neonatal status epilepticus showed abnormal social behavior characterized by deficit in social discrimination and enhanced emotionality. Taking into account that early insult can produce different biological manifestations in a gender-dependent manner, we aimed to investigate the social behavior and anxiety-like behavior in female Wistar rats following early life seizures. Neonate female Wistar rats at 9 days postnatal were subject to pilocarpine-induced status epilepticus and the control received saline. Behavioral tests started from 60 days postnatal and were carried out only during the diestrus phase of the reproductive cycle. In sociability test experimental animals exhibited reduced motivation for social encounter and deficit in social discrimination. In open field and the elevated plus maze, experimental animals showed enhanced emotionality with no changes in basal locomotor activity. The results showed that female rats submitted to neonatal status epipepticus showed impaired social behavior, characterized by reduced motivation to novelty and deficit in social discrimination in addition to enhanced emotionality.

Report of the evaluation by the Ad Hoc Review Committee on Materials Science Research. Ex-post evaluation in fiscal year 2003

International Nuclear Information System (INIS)

2004-06-01

The Research Evaluation Committee, which consisted of 13 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Materials Science Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the adequacy of the R and D results achieved for five years until Fiscal Year 2002 at Department of Materials Science in Tokai Research Establishment of JAERI. The Ad Hoc Review Committee consisted of eight specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from October 2003 to February 2004. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on November 14, 2003, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on March 8, 2004. This report describes the result of the evaluation by the Ad Hoc Review Committee on Materials Science Research. (author)

Report of the evaluation by the Ad Hoc Review Committee on Computational Science and Engineering. Result evaluation in fiscal year 2000

International Nuclear Information System (INIS)

2001-06-01

The Research Evaluation Committee, which consisted of 14 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Computational Science and Engineering in accordance with the 'Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the R and D accomplishments achieved for five years from Fiscal Year 1995 to Fiscal Year 1999 at Center for Promotion of Computational Science and Engineering of JAERI. The Ad Hoc Review Committee consisted of seven specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from December 2000 to March 2001. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on December 27, 2000, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on March 16, 2001. This report describes the result of the evaluation by the Ad Hoc Review Committee on Computational Science and Engineering. (author)

Clinical and radiographic evaluation of early loaded narrow-diameter implants

DEFF Research Database (Denmark)

Maiorana, Carlo; King, Paul; Quaas, Sebastian

2015-01-01

OBJECTIVE: To evaluate the clinical reliability of narrow implants placed in a one-stage procedure and early loaded in the upper and lower incisor region. MATERIAL AND METHODS: This is a prospective, single-arm, multicenter study in which patients with missing natural dentition in upper lateral a...... be considered as a valid solution in the treatment of the localized narrow bony defects in the anterior area with reduced spaces between the natural teeth....... healing period. Clinical and radiographic checks were performed at implant placement, loading, and at the 6, 12, 24, and 36 months follow-up visits. RESULTS: A total of 69 subjects with 97 implants have been included in this study. From surgery to 36 months follow-up, 5.6% of the implants showed bone loss...... loss between loading and the 1-year follow-up visit (Galindo-Moreno et al. 2012). This finding, associated with a stable probing pocket depth and a stable crown-gingiva distance, using a one-stage surgical procedure helps to maintain the integrity of the peri-implant soft tissues. Narrow implants can...

Directory of AFRL/HEA Technical Publications Submitted to DTIC from 1969 to 2007

National Research Council Canada - National Science Library

Bell, Herbert H; Casey, Elizabeth P

2007-01-01

...) has submitted technical publications to the Defense Technical Information Center (DTIC) documenting the unique research and development efforts conducted by this organization to improve warfighter training...

LNG Safety Assessment Evaluation Methods

Energy Technology Data Exchange (ETDEWEB)

Muna, Alice Baca [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); LaFleur, Angela Christine [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2015-05-01

Sandia National Laboratories evaluated published safety assessment methods across a variety of industries including Liquefied Natural Gas (LNG), hydrogen, land and marine transportation, as well as the US Department of Defense (DOD). All the methods were evaluated for their potential applicability for use in the LNG railroad application. After reviewing the documents included in this report, as well as others not included because of repetition, the Department of Energy (DOE) Hydrogen Safety Plan Checklist is most suitable to be adapted to the LNG railroad application. This report was developed to survey industries related to rail transportation for methodologies and tools that can be used by the FRA to review and evaluate safety assessments submitted by the railroad industry as a part of their implementation plans for liquefied or compressed natural gas storage ( on-board or tender) and engine fueling delivery systems. The main sections of this report provide an overview of various methods found during this survey. In most cases, the reference document is quoted directly. The final section provides discussion and a recommendation for the most appropriate methodology that will allow efficient and consistent evaluations to be made. The DOE Hydrogen Safety Plan Checklist was then revised to adapt it as a methodology for the Federal Railroad Administration’s use in evaluating safety plans submitted by the railroad industry.

Psychometric evaluation of the general health questionnaire-12 and Rosenberg self-esteem scale in Hungarian and Slovak early adolescents

NARCIS (Netherlands)

Sarkova, M.; Nagyova, I.; Katreniakova, Z.; Geckova, A.M.; Orosova, O.; Middel, B.; van Dijk, J.P.; van den Heuvel, W.

2006-01-01

The reliability and factor structure of the General Health Questionnaire-12 (GHQ-12) and the Rosenberg Self-Esteem scale (RSE) were evaluated in samples of Hungarian and Slovak early adolescents. The principal component analyses support the two-factor solution for GHQ-12 with subscales

Emergency evacuation/transportation plan update: Traffic model development and evaluation of early closure procedures. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1993-10-28

Prolonged delays in traffic experienced by Laboratory personnel during a recent early dismissal in inclement weather, coupled with reconstruction efforts along NM 502 east of the White Rock Wye for the next 1 to 2 years, has prompted Los Alamos National Laboratory (LANL) to re-evaluate and improve the present transportation plan and its integration with contingency plans maintained in other organizations. Facilities planners and emergency operations staff need to evaluate the transportation system`s capability to inefficiently and safely evacuate LANL under different low-level emergency conditions. A variety of potential procedures governing the release of employees from the different technical areas (TAs) requires evaluation, perhaps with regard to multiple emergency-condition scenarios, with one or more optimal procedures ultimately presented for adoption by Lab Management. The work undertaken in this project will hopefully lay a foundation for an on-going, progressive transportation system analysis capability. It utilizes microscale simulation techniques to affirm, reassess and validate the Laboratory`s Early Dismissal/Closure/Delayed Opening Plan. The Laboratory is required by Federal guidelines, and compelled by prudent practice and conscientious regard for the welfare of employees and nearby residents, to maintain plans and operating procedures for evacuation if the need arises. The tools developed during this process can be used outside of contingency planning. It is anticipated that the traffic models developed will allow site planners to evaluate changes to the traffic network which could better serve the normal traffic levels. Changes in roadway configuration, control strategies (signalization and signing), response strategies to traffic accidents, and patterns of demand can be modelled using the analysis tools developed during this project. Such scenarios typically are important considerations in master planning and facilities programming.

Report of the evaluation by the Ad Hoc Review Committee on Health Physics. Result evaluation in fiscal year 2000

International Nuclear Information System (INIS)

2001-06-01

The Research Evaluation Committee, which consisted of 14 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Health Physics in accordance with the 'Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the R and D accomplishments achieved for five years from Fiscal Year 1995 to Fiscal Year 1999 at Department of Health Physics in Tokai Research Establishment and at related departments in other Establishments of JAERI. The Ad Hoc Review Committee consisted of six specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from October 2000 to January 2001. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on October 10, 2000, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on March 16, 2001. This report describes the result of the evaluation by the Ad Hoc Review Committee on Health Physics. (author)

Discussion of submitted posters for Section 2.3 (Rangeland Germplasm Resources)

Science.gov (United States)

As part of the IX International Rangeland Congress held in Rosario, Argentina, a total of 70 posters from 17 countries were submitted to Section 2.3 (Rangeland Germplasm Resources). These posters documented research conducted in five major regions of the world: South America, North America, Africa...

15 CFR 711.2 - Who submits declarations, reports, and advance notifications.

Science.gov (United States)

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Who submits declarations, reports, and advance notifications. 711.2 Section 711.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS...

40 CFR 63.6009 - What notifications must I submit and when?

Science.gov (United States)

2010-07-01

... National Emissions Standards for Hazardous Air Pollutants: Rubber Tire Manufacturing Notifications, Reports... this subpart. (d) If you are required to conduct a performance test, you must submit a notification of intent to conduct a performance test at least 60 calendar days before the performance test is scheduled...

LHCb Early Career Scientist Awards

CERN Multimedia

Patrick Koppenburg for the LHCb Collaboration

2016-01-01

On 15 September 2016, the LHCb collaboration awarded the first set of prizes for outstanding contributions of early career scientists.   From left to right: Guy Wilkinson (LHCb spokesperson), Sascha Stahl, Kevin Dungs, Tim Head, Roel Aaij, Conor Fitzpatrick, Claire Prouvé, Patrick Koppenburg (chair of committee) and Sean Benson. Twenty-five nominations were submitted and considered by the committee, and 5 prizes were awarded to teams or individuals for works that had a significant impact within the last year. The awardees are: Roel Aaij, Sean Benson, Conor Fitzpatrick, Rosen Matev and Sascha Stahl for having implemented and commissioned the revolutionary changes to the LHC Run-2 high-level-trigger, including the first widespread deployment of real-time analysis techniques in High Energy Physics;   Kevin Dungs and Tim Head for having launched the Starterkit initiative, a new style of software tutorials based on modern programming methods. “Starterkit is a group of ph...

25 CFR 516.2 - When may a person to whom this part applies give testimony, make a statement or submit to interview?

Science.gov (United States)

2010-04-01

... testimony, make a statement or submit to interview? 516.2 Section 516.2 Indians NATIONAL INDIAN GAMING... whom this part applies give testimony, make a statement or submit to interview? (a) No person to whom... regulation, shall provide testimony, make a statement or submit to interview. (b) Whenever a subpoena...

Evaluation of CASP8 model quality predictions

KAUST Repository

Cozzetto, Domenico; Kryshtafovych, Andriy; Tramontano, Anna

2009-01-01

established a prediction category to evaluate their performance in 2006. In 2008 the experiment was repeated and its results are reported here. Participants were invited to infer the correctness of the protein models submitted by the registered automatic

Prevalence of gallstones in 1,229 patients submitted to surgical laparoscopic treatment of GERD and esophageal achalasia: associated cholecystectomy was a safe procedure.

Science.gov (United States)

Sallum, Rubens Antonio Aissar; Padrão, Eduardo Messias Hirano; Szachnowicz, Sergio; Seguro, Francisco C B C; Bianchi, Edno Tales; Cecconello, Ivan

2015-01-01

Association between esophageal achalasia/ gastroesophageal reflux disease (GERD) and cholelithiasis is not clear. Epidemiological data are controversial due to different methodologies applied, the regional differences and the number of patients involved. Results of concomitant cholecistectomy associated to surgical treatment of both diseases regarding safety is poorly understood. To analyze the prevalence of cholelithiasis in patients with esophageal achalasia and gastroesophageal reflux submitted to cardiomyotomy or fundoplication. Also, to evaluate the safety of concomitant cholecistectomy. Retrospective analysis of 1410 patients operated from 2000 to 2013. They were divided into two groups: patients with GERD submitted to laparocopic hiatoplasty plus Nissen fundoplication and patients with esophageal achalasia to laparoscopic cardiomyotomy plus partial fundoplication. It was collected epidemiological data, specific diagnosis and subgroups, the presence or absence of gallstones, surgical procedure, operative and clinical complications and mortality. All groups/subgroups were compared. From 1,229 patients with GERD or esophageal achalasia, submitted to laparoscopic cardiomyotomy or fundoplication, 138 (11.43%) had cholelitiasis, occurring more in females (2.38:1) with mean age of 50,27 years old. In 604 patients with GERD, 79 (13,08%) had cholelitiasis. Lower prevalence occurred in Barrett's esophagus patients 7/105 (6.67%) (p=0.037). In 625 with esophageal achalasia, 59 (9.44%) had cholelitiasis, with no difference between chagasic and idiopathic forms (p=0.677). Complications of patients with or without cholecystectomy were similar in fundoplication and cardiomyotomy (p=0.78 and p=1.00).There was no mortality or complications related to cholecystectomy in this series. Prevalence of cholelithiasis was higher in patients submitted to fundoplication (GERD). Patients with chagasic or idiopatic forms of achalasia had the same prevalence of cholelithiasis. Gallstones

Adaptação transcultural e consistência interna do Early Trauma Inventory (ETI Early Trauma Inventory (ETI: cross-cultural adaptation and internal consistency

Directory of Open Access Journals (Sweden)

Marcelo Feijó de Mello

2010-04-01

Full Text Available As experiências traumáticas precoces são um fator de risco preditivo de problemas psicopatológicos futuros. O Early Trauma Inventory (ETI é um instrumento que avalia em indivíduos adultos experiências traumáticas ocorridas antes dos 18 anos de idade. Tal instrumento foi traduzido, transculturalmente adaptado e sua consistência interna foi avaliada. Vítimas de violência que preencheram os critérios de inclusão e exclusão foram submetidas a uma entrevista diagnóstica (SCID-I e ao ETI. Foram incluídos 91 pacientes com o transtorno do estresse pós-traumático (TEPT. O alfa de Cronbach nos diferentes domínios variou de 0,595-0,793, e o escore total foi de 0,878. A maior parte dos itens nos vários domínios, com exceção do abuso emocional, apresentou índices de correlação interitem entre 0,51-0,99. A versão adaptada foi útil tanto na clínica quanto na pesquisa. Apresentou boa consistência interna e na correlação interitem. O ETI é um instrumento válido, com boa consistência para se avaliar a presença de história de traumas precoces em indivíduos adultos.Early life stress is a strong predictor of future psychopathology during adulthood. The Early Trauma Inventory (ETI was developed to detect the presence and impact of traumatic experiences that occurred up to 18 years of age. The ETI was translated and cross-culturally adapted and had its consistency evaluated. Victims of violence that met the inclusion and exclusion criteria were submitted to SCID-I and ETI. Ninety-one patients with post-traumatic stress disorder (PTSD were included. Cronbach's alpha in the different domains varied from 0.595 to 0.793, and the total score was 0.878. Except for emotional abuse, most of the various domains displayed inter-item correlation rates of 0.51 to 0.99. The adapted version was useful for clinical and research purposes and showed good internal consistency and inter-item correlation. The ETI is a valid instrument with good

Aiming for a simpler early arthritis MRI protocol

DEFF Research Database (Denmark)

Stomp, Wouter; Krabben, Annemarie; van der Heijde, Désirée

2015-01-01

PURPOSE: To evaluate whether intravenous gadolinium (Gd) contrast administration can be eliminated when evaluating synovitis and tenosynovitis in early arthritis patients, thereby decreasing imaging time, cost, and invasiveness. MATERIALS AND METHODS: Wrist MRIs of 93 early arthritis patients wer...

Vrancea early warning system for Bucharest and industrial objectives

International Nuclear Information System (INIS)

Ionescu, C.; Marmureanu, A.; Grigore, A.; Tataru, D.

2005-01-01

Romania is an earthquake prone area and it is of crucial importance to obtain quantitative information needed for seismic risk mitigation and related public policies and seismic safety measures. The most damaging earthquakes in Romania concentrate in the Vrancea region, located at the sharp bend of the Eastern Carpathians Arc, in a well confined focal volume at intermediate depths between 60 km and 200 km.Vrancea earthquakes are documented for at least a millennium (since 985 a.c.) and represent very peculiar characteristics. They are a permanent threat for large urban areas on the Romanian territory and extended areas in Europe. Bucharest is among the cities mostly affected by destructive earthquakes. The early warning system in Romania is to provide individuals and communities exposed to disaster risk given by strong Vrancea earthquakes, with accurate information about an impending hazard as early as possible, to act in a timely and appropriate manner to reduce probability of suffering, personal damage, death and property losses. The purpose of this early system is to issue messages at sites of interest before the destructive seismic energy arrives. Early warning system is a technological instrument to detect, monitor and submit warnings/alerts. It needs to become part of a management information system for decision - making in the context of national institutional frameworks for disaster management and as a part of national and local strategies for disaster risk reduction. (authors)

Effect of Erythrina velutina and Erythrina mulungu in rats submitted to animal models of anxiety and depression

Directory of Open Access Journals (Sweden)

M.D. Ribeiro

2006-02-01

Full Text Available Erythrina velutina (EV and Erythrina mulungu (EM, popularly used in Brazil as tranquilizing agents, were studied. The effects of acute and chronic oral treatment with a water:alcohol extract of EV (7:3, plant grounded stem bark; acute = 100, 200, 400 mg/kg; chronic = 50, 100, 200 mg/kg were evaluated in rats (N = 11-12 submitted to the elevated T-maze (for avoidance and escape measurements model of anxiety. This model was selected for its presumed capacity to elicit specific subtypes of anxiety disorders recognized in clinical practice: avoidance has been related to generalized anxiety and escape to panic. Additionally, animals were treated with the same doses of EV and EM (water:alcohol 7:3, inflorescence extract and submitted to the forced swim test for the evaluation of antidepressant activity (N = 7-10. Both treatment regimens with EV impaired elevated T-maze avoidance latencies, without altering escape, in a way similar to the reference drug diazepam (avoidance 1, mean ± SEM, acute study: 131.1 ± 45.5 (control, 9.0 ± 3.3 (diazepam, 12.7 ± 2.9 (200 mg/kg, 28.8 ± 15.3 (400 mg/kg; chronic study: 131.7 ± 46.9 (control, 35.8 ± 29.7 (diazepam, 24.4 ± 10.4 (50 mg/kg, 29.7 ± 11.5 (200 mg/kg. Neither EV nor EM altered measurements performed in the forced swim test, in contrast to the reference drug imipramine that significantly decreased immobility time after chronic treatment. These results were not due to motor alterations since no significant effects were detected in an open field. These observations suggest that EV exerts anxiolytic-like effects on a specific subset of defensive behaviors which have been associated with generalized anxiety disorder.

¹⁸F-FDG PET/CT-based early treatment response evaluation of nanoparticle-assisted photothermal cancer therapy

DEFF Research Database (Denmark)

Norregaard, Kamilla; Jørgensen, Jesper T.; Simón, Marina

2017-01-01

Within the field of nanoparticle-assisted photothermal cancer therapy, focus has mostly been on developing novel heat-generating nanoparticles with the right optical and dimensional properties. Comparison and evaluation of their performance in tumor-bearing animals are commonly assessed by changes...... in tumor volume; however, this is usually a late-occurring event. This study implements 2-deoxy-2-[F-18]fluoro-D-glucose positron emission tomography imaging to perform early evaluation of the treatment outcome of photothermal therapy. Silica-gold nanoshells (NS) are administered intravenously to nude mice...

Analysis of final year DVM research projects submitted to the Faculty ...

African Journals Online (AJOL)

This study analyzed the intellectual output of the undergraduate final year students. research projects submitted to the Faculty of Veterinary Medicine, Usmanu Danfodiyo University, Sokoto, from 1994 to 2004. The findings of the study show that a total of 194 research projects were produced within the period under study.

30 CFR 210.105 - May I submit these production reports manually?

Science.gov (United States)

2010-07-01

... addressed to Minerals Management Service, P.O. Box 17110, Denver, Colorado 80217-0110; or (2) Special... 30 Mineral Resources 2 2010-07-01 2010-07-01 false May I submit these production reports manually? 210.105 Section 210.105 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR...

20 CFR 645.415 - What planning information must a State submit in order to receive a formula grant?

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What planning information must a State submit in order to receive a formula grant? 645.415 Section 645.415 Employees' Benefits EMPLOYMENT AND... Grants Administration § 645.415 What planning information must a State submit in order to receive a...

Audit of the autoantibody test, EarlyCDT®-lung, in 1600 patients: an evaluation of its performance in routine clinical practice.

Science.gov (United States)

Jett, James R; Peek, Laura J; Fredericks, Lynn; Jewell, William; Pingleton, William W; Robertson, John F R

2014-01-01

EarlyCDT(®)-Lung may enhance detection of early stage lung cancer by aiding physicians in assessing high-risk patients through measurement of biological markers (i.e., autoantibodies). The test's performance characteristics in routine clinical practice were evaluated by auditing clinical outcomes of 1613 US patients deemed at high risk for lung cancer by their physician, who ordered the EarlyCDT-Lung test for their patient. Clinical outcomes for all 1613 patients who provided HIPAA authorization are reported. Clinical data were collected from each patient's treating physician. Pathology reports when available were reviewed for diagnostic classification. Staging was assessed on histology, otherwise on imaging. Six month follow-up for the positives/negatives was 99%/93%. Sixty-one patients (4%) were identified with lung cancer, 25 of whom tested positive by EarlyCDT-Lung (sensitivity=41%). A positive EarlyCDT-Lung test on the current panel was associated with a 5.4-fold increase in lung cancer incidence versus a negative. Importantly, 57% (8/14) of non-small cell lung cancers detected as positive (where stage was known) were stage I or II. EarlyCDT-Lung has been extensively tested and validated in case-control settings and has now been shown in this audit to perform in routine clinical practice as predicted. EarlyCDT-Lung may be a complementary tool to CT for detection of early lung cancer. Copyright © 2013 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

Early postoperative repair status after rotator cuff repair cannot be accurately classified using questionnaires of patient function and isokinetic strength evaluation.

Science.gov (United States)

Colliver, Jessica; Wang, Allan; Joss, Brendan; Ebert, Jay; Koh, Eamon; Breidahl, William; Ackland, Timothy

2016-04-01

This study investigated if patients with an intact tendon repair or partial-thickness retear early after rotator cuff repair display differences in clinical evaluations and whether early tendon healing can be predicted using these assessments. We prospectively evaluated 60 patients at 16 weeks after arthroscopic supraspinatus repair. Evaluation included the Oxford Shoulder Score, 11-item version of the Disabilities of the Arm, Shoulder and Hand, visual analog scale for pain, 12-item Short Form Health Survey, isokinetic strength, and magnetic resonance imaging (MRI). Independent t tests investigated clinical differences in patients based on the Sugaya MRI rotator cuff classification system (grades 1, 2, or 3). Discriminant analysis determined whether intact repairs (Sugaya grade 1) and partial-thickness retears (Sugaya grades 2 and 3) could be predicted. No differences (P repair was intact. The ability to discriminate between groups was enhanced with up to 5 variables entered; however, only 87% of the partial-retear group and 36% of the intact-repair group were correctly classified. No differences in clinical scores existed between patients stratified by the Sugaya MRI classification system at 16 weeks. An intact repair or partial-thickness retear could not be accurately predicted. Our results suggest that correct classification of healing in the early postoperative stages should involve imaging. Copyright © 2016 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

EARLY ENTRANCE COPRODUCTION PLANT

Energy Technology Data Exchange (ETDEWEB)

John S. Abughazaleh; Mushtaq Ahmed; Ashok Anand; John H. Anderson; Charles Benham; Fred D. Brent; Thomas E. Chance; William K. Davis; Raymond F. Drnevich; Larry Hall; Ming He; Stephen A. Lang; David Mintner; Wendy Moore; Jimmy O. Ong; George Potoczniak; Adela G. Sanchez; Charles H. Schrader; Lalit S. Shah; Kalapi D. Sheth; Phil J. Shires; Rae Song

2001-05-17

The overall objective of this project is the three-phase development of an Early Entrance Coproduction Plant (EECP) that produces at least one product from at least two of the following three categories: Electric power (or heat); Fuels; and Chemicals. The objective is to have these products produced by technologies capable of using synthesis gas derived from coal and/or some other carbonaceous feedstock, such as petroleum coke. The objective of Phase I was to determine the feasibility and define the concept for the EECP located at a specific site and to develop a Research, Development, and Testing (RD and T) Plan for implementation in Phase II. This objective has now been accomplished. A specific site, Motiva Refinery in Port Arthur, Texas, has been selected as the location best suited for the EECP. The accomplishments of Phase I are discussed in detail in this Phase I Concept Report. A RD and T Plan and a preliminary project financing plan have been developed and are submitted separately from this report.

Early food for future health: a randomized controlled trial evaluating the effect of an eHealth intervention aiming to promote healthy food habits from early childhood.

Science.gov (United States)

Helle, Christine; Hillesund, Elisabet Rudjord; Omholt, Mona Linge; Øverby, Nina Cecilie

2017-09-20

Childhood overweight and obesity is a global public health challenge. Primary prevention initiatives targeting parents have been called for to encourage a positive feeding environment and healthy eating habits that may lay a good foundation for future health. At the same time, there is a need for interventions which combine accessibility and scalability with cost effectiveness. Today's parents are extensive Internet-users, but only a few randomized controlled trials have investigated the use of Internet to promote healthy eating habits in early childhood. In Early Food for Future Health we have developed and will evaluate an Internet-based tool for parents of children between 6 and 12 months, aiming to increase knowledge about infant nutrition and foster protective feeding behavior. During springtime 2016, parents of children aged between 3 and 5 months were recruited through Norwegian child health centres and announcements on Facebook. After completing the baseline questionnaire, 718 parents were individually randomized to intervention- or control group. The intervention group received monthly emails with links to an age-appropriate web-site when their child was between 6 and 12 months. The control group received ordinary care from the child health centres. The data-collection is ongoing. All participants will be followed up at ages 12 and possibly 24 and 48 months, with questionnaires relating to eating behaviour and feeding practices, food variety and diet quality. Providing guidance and counseling to parents of infants is an important task for health authorities and the public child health services. Early Food for Future health is an intervention focusing on promoting early healthy food-habits which may prevent childhood overweight and obesity. If proven to be effective, Early Food for Future Health can be used by parents and public health nurses for supplementary guidance on feeding practices and diet. This study has the potential to provide greater

Dental bleaching on teeth submitted to enamel microabrasion 30 years ago-a case report of patients' compliance during bleaching treatment.

Science.gov (United States)

Sundfeld, Daniel; Pavani, Caio Cesar; Schott, Timm Cornelius; Machado, Lucas Silveira; Pini, Núbia Inocêncya Pavesi; Bertoz, André Pinheiro de Magalhães; Sundfeld, Renato Herman

2018-04-20

The present dental bleaching case report describes a new method that precisely quantifies the daily wearing-times of the bleaching product by inserting a microsensor in the acetate custom tray. The bleaching efficacy was also discussed since the patient was previously submitted to enamel microabrasion. The patient was submitted to enamel microabrasion in 1987, and bleaching treatment was performed in 2005. In 2017, re-bleaching was executed using 10% peroxide carbamide. The electronic microsensor, TheraMon (TheraMon® microelectronic system; Sales Agency Gschladt, Hargelsberg, Austria), was embedded in the labial region of the upper and lower acetate trays to evaluate the wearing-times of the acetate trays/bleaching product. The patient was instructed to wear the tray for 6 to 8 h/day while sleeping. After 24 days of bleaching treatment, the data obtained from the TheraMon electronic devices was collected and interpreted. The patient did not entirely follow the bleaching treatment as recommended, as there was no evidence of use of the upper and lower trays for some days; additionally, the bleaching product was used for shorter and longer periods than was instructed. The TheraMon microeletronic device precisely measured the wearing-times of the acetate tray/bleaching product during the bleaching treatment. Teeth submitted to enamel microabrasion presented with a healthy clinical appearance after 30 years. Measuring the length and frequency of use of an acetate tray/bleaching product can be important to clinicians and patients for obtaining a controlled and adequate bleaching treatment.

Clinical role of early dynamic FDG-PET/CT for the evaluation of renal cell carcinoma

Energy Technology Data Exchange (ETDEWEB)

Nakajima, Reiko; Abe, Koichiro; Sakai, Shuji [Tokyo Women' s Medical University, Department of Diagnostic Imaging and Nuclear Medicine, Tokyo (Japan); Kondo, Tsunenori; Tanabe, Kazunari [Tokyo Women' s Medical University, Department of Urology, Tokyo (Japan)

2016-06-15

We studied the usefulness of early dynamic (ED) and whole-body (WB) FDG-PET/CT for the evaluation of renal cell carcinoma (RCC). One hundred patients with 107 tumours underwent kidney ED and WB FDG-PET/CT. We visually and semiquantitatively evaluated the FDG accumulation in RCCs in the ED and WB phases, and compared the accumulation values with regard to histological type (clear cell carcinoma [CCC] vs. non-clear cell carcinoma [N-CCC]), the TNM stage (high stage [3-4] vs. low stage [1-2]), the Fuhrman grade (high grade [3-4] vs. low grade [1-2]) and presence versus absence of venous (V) and lymphatic (Ly) invasion. In the ED phase, visual evaluation revealed no significant differences in FDG accumulation in terms of each item. However, the maximum standardized uptake value and tumour-to-normal tissue ratios were significantly higher in the CCCs compared to the N-CCCs (p < 0.001). In the WB phase, in contrast, significantly higher FDG accumulation (p < 0.001) was found in RCCs with a higher TNM stage, higher Furman grade, and the presence of V and Ly invasion in both the visual and the semiquantitative evaluations. ED and WB FDG-PET/CT is a useful tool for the evaluation of RCCs. (orig.)

Evaluation of early and late complications in patients with congenital lobar emphysema: A 12 year experience

Directory of Open Access Journals (Sweden)

Nazem Masood

2010-01-01

Full Text Available Background: Congenital lobar emphysema (CLE is characterised by over distension of one lobe and pressure on the adjacent lobe and mediastinum. In this study, we review the pathological results of our paediatric patients with CLE, highlighting the early and late complications that occurred in these patients. Patients and Methods: In a prospective study from 1996 to 2008, we evaluated 30 patients with CLE diagnosis. Variables collected included sex, age at the time of diagnosis, radiological diagnostic method, type of treatment, pathological analysis, surgical findings and early postoperative complications. Parents were asked to refer to our clinic for follow-up and evaluation of late complications. Results: Thirty patients and males accounted for majority of the study population (n = 20, 67%. The mean age of male and female patients (at admission was 7.2 ± 2.3 and 4.7 ± 1.2 months respectively (P = not significant. The main diagnostic method was chest x-ray (CXR in all patients. Abnormal bronchial cartilage was found in 71% of patients. The most affected lobe was left upper lobe (50%. Associated anomalies were seen in four patients. Early postoperative periodhadtwo cases of pneumothoraces. At six month follow up, five (25% males and four females (40% had delayed weight gain. Permanent oxygen dependency was seen in two patients. Twenty- six patients underwent thoracotomy. Mortality rate was 13%. Base deficit at the time of admission was greater in those patients who eventually died, (-8.6 ± 1.2 versus -3.1 ± 0.4 (P = 0.0003. There were two deaths in the bilobar involvement group and two in the unilobar involvement group (P = 0.07, near significant. Conclusion: This study confirms that the number of affected lobes and base deficit at the time of admission were associated with significantly increased mortality.

EARLY CHILDHOOD MENTAL HEALTH CONSULTATION: AN EVALUATION OF EFFECTIVENESS IN A RURAL COMMUNITY.

Science.gov (United States)

Vuyk, M Alexandra; Sprague-Jones, Jessica; Reed, Christie

2016-01-01

Little research has been done to evaluate the effectiveness of early childhood mental health consultation (ECMHC) in rural, applied settings. In this mixed-methods study, we evaluated an approach to ECMHC used in rural Southwest Kansas with individualized services for childcare providers. Twenty-nine home-based and center-based childcare providers completed measures on provider growth, perceptions of child outcomes, and satisfaction with sessions. In total, 162 data points were collected and analyzed using multilevel growth models. In addition, 16 providers participated in qualitative interviews. Both home-based and center-based providers reported very high satisfaction with consultation sessions which increased with time, although home-based providers showed significantly higher satisfaction than did center-based providers. Provider growth, encompassing personal well-being, scheduling and transitions, connections with parents, and positive discipline strategies increased significantly over time. Child outcomes, encompassing prosocial behavior, resilience, and overall well-being also improved significantly in providers' perception. ECMHC as conducted in Southwest Kansas appears to have a positive effect on childcare providers and the children in their care. © 2015 Michigan Association for Infant Mental Health.

20 CFR 667.120 - What planning information must a State submit in order to receive a formula grant?

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What planning information must a State submit in order to receive a formula grant? 667.120 Section 667.120 Employees' Benefits EMPLOYMENT AND... INVESTMENT ACT Funding § 667.120 What planning information must a State submit in order to receive a formula...

Report of the evaluation by the Ad Hoc Review Committee on Information Technology. In-advance evaluation in fiscal year 2000

International Nuclear Information System (INIS)

2001-06-01

The Research Evaluation Committee, which consisted of 14 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Information Technology in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the adequacy of the R and D programs pertaining to the establishment and utilization of the Information Technology Based Laboratory (ITBL) to be implemented for five years starting in Fiscal Year 2001 at Center for Promotion of Computational Science and Engineering and Department of Environmental Sciences of JAERI. The Ad Hoc Review Committee consisted of eight specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from February to March 2001. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on February 9, 2001, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on March 16, 2001. This report describes the result of the evaluation by the Ad Hoc Review Committee on Information Technology. (author)

Report of the evaluation by the Ad Hoc Review Committee on Nuclear Safety Research. Result evaluation in fiscal year 2000

International Nuclear Information System (INIS)

2001-06-01

The Research Evaluation Committee, which consisted of 14 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Nuclear Safety Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the R and D accomplishments achieved for five years from Fiscal Year 1995 to Fiscal Year 1999 at Department of Reactor Safety Research, Department of Fuel Cycle Safety Research, Department of Environmental Safety Research and Department of Safety Research Technical Support in Tokai Research Establishment at JAERI. The Ad Hoc Review Committee consisted of 11 specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from December 2000 to February 2001. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on December 11, 2000, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on March 16, 2001. This report describes the result of the evaluation by the Ad Hoc Review Committee on Nuclear Safety Research. (author)

5th environmental report submitted by the Hessian Government

International Nuclear Information System (INIS)

1992-01-01

The 5th environmental report submitted by the Hessian Government informs about the success of environmental policies in the period under review and discuss the future tasks and targets with emphasis on I) environmental quality in Hesse (A. Nature and ladscape, B. water, C. air, D. noise, E. chemicals, industrial monitoring, F. wastes, G. pollutants in the food chain, H. radioactivity and radiation protection), II) selected instruments and points of main effort, III) work and environment; Appendix. (BBR) [de

34 CFR 656.10 - What combined application may an institution submit?

Science.gov (United States)

2010-07-01

... LANGUAGE AND AREA STUDIES OR FOREIGN LANGUAGE AND INTERNATIONAL STUDIES How Does One Apply for a Grant... 34 Education 3 2010-07-01 2010-07-01 false What combined application may an institution submit? 656.10 Section 656.10 Education Regulations of the Offices of the Department of Education (Continued...

40 CFR 63.9350 - What reports must I submit and when?

Science.gov (United States)

2010-07-01

... new or reconstructed affected source that must meet the emission limitation, you must submit a... there is no deviation from the applicable emission limitation and the CEMS or CPMS was not out-of... reconstructed engine test cell/stand during the reporting period. (3) A summary of the total duration of the...

30 CFR 210.55 - May I submit this royalty report manually?

Science.gov (United States)

2010-07-01

... to Minerals Management Service, P.O. Box 5810, Denver, Colorado 80217-5810; or (2) Special courier or... 30 Mineral Resources 2 2010-07-01 2010-07-01 false May I submit this royalty report manually? 210.55 Section 210.55 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS...

Disfagia orofaríngea em pacientes submetidos à entubação orotraqueal Oropharyngeal dysphagia in patients submitted to orotracheal intubation

Directory of Open Access Journals (Sweden)

Michele Ramos Grigio Kunigk

2007-12-01

Full Text Available OBJETIVO: Detectar e caracterizar as alterações da fase oral e faríngea da deglutição, bem como verificar a ocorrência de penetração e aspiração laríngeas em pacientes submetidos à entubação orotraqueal. MÉTODOS: O estudo incluiu 30 adultos internados na unidade de tratamento intensivo do Hospital Estadual Mário Covas, que receberam entubação orotraqueal no período de 40 horas a 15 dias. Todos foram submetidos, por duas vezes, à avaliação endoscópica da deglutição, na primeira e segunda semanas, após a extubação, sendo observadas as alterações da fase oral e faríngea da deglutição e a presença de penetração e aspiração laríngeas. RESULTADOS: Na primeira avaliação, as alterações da fase oral estiveram presentes em 19(63,3% pacientes e, na segunda, em 12(40%.As alterações da fase faríngea ocorreram na primeira avaliação em 27(90% pacientes e, na segunda, em 8(26,7%. A penetração e a aspiração laríngeas foram detectadas nas duas avaliações, sendo diferentes para cada consistência e volume testados. CONCLUSÃO: A população submetida à entubação orotraqueal após a extubação apresenta alterações das fases oral e faríngea da deglutição caracterizadas por uma variedade de comprometimentos e acompanhadas de penetração e aspiração laríngeas.PURPOSE: To detect and characterize alterations in the oropharyngeal phase of swallowing as well as to verify the occurrence of laryngeal penetration and aspiration in patients submitted to invasive mechanical ventilation. METHODS: The study consisted of 30 individuals hospitalized in the intensive care unit of the Mario Covas State Hospital, who received invasive mechanical ventilation. They were all submitted twice to endoscopic evaluation for swallowing disorders in the first and second week after extubation. Alterations were observed in the oro-pharyngeal phase of swallowing and also the presence of penetration and laryngeal aspiration

Tit-For-Tat Strategy for Increasing Medical Student Evaluation Response Rates

Directory of Open Access Journals (Sweden)

Matthew G. Malone

2017-12-01

Full Text Available Introducation It is essential for faculty to receive feedback on their teaching for the purpose of improvement as well as promotion. It can be challenging to motivate students to provide feedback to preceptors and fill out evaluation forms when not a clerkship requirement. Furthermore, there is concern that making the evaluations a requirement can compromise the quality of the feedback. The objective of this study was to identify an increase in the number of faculty and resident evaluations completed by students rotating through their Emergency Medicine clerkship following the implementation of a tit-for-tat incentive strategy. Method Prior to the implementation of Tit-for-Tat, students rotating through their emergency medicine clerkship were asked to fill out evaluations of residents and faculty members with whom they worked. These were encouraged but voluntary. Beginning in the 2014–2015 academic year, a tit-for-tat strategy was employed whereby students had to complete a resident or faculty evaluation in order to view the student assessment completed by that resident or faculty preceptor. Results Students submitted 1101 evaluations in the control, with a mean of 3.60 evaluations completed per student and 3.77 evaluations received per preceptor. Following the implementation of tit-for-tat, students submitted 2736 evaluations, with a mean of 8.19 evaluations completed per student and 7.52 evaluations received per preceptor. Both the increase in evaluations completed per student and evaluations received per preceptor were statistically significant with p-value <0.001. Conclusion The tit-for-tat strategy significantly increased the number of evaluations submitted by students rotating through their emergency medicine clerkship. This has served as an effective tool to increase the overall number of evaluations completed, the number of evaluations each instructor received on average and the proportion of students that completed evaluations

Toward an African-Christian Demonology: The Demonologies of African Traditional Religion, African Christianity, and Early Christianity in Dialogue

OpenAIRE

Moscicke, Hans

2017-01-01

Christian interactions with the spirit-world of African traditional religion (ATR) have remained problematic due, in part, to the failure of Christian missionaries to understand in detail the cosmology of ATR and the angelologies and demonologies of early Christianity. In this article I suggest a way beyond this impasse. I first survey the shape of cosmology and demonology in ATR, and then examine African Christianitys variegated responses to these traditional beliefs. Finally, I submit that ...

Summary of Country Reports Submitted to the Energy Efficiency Working Party: October 2011

Energy Technology Data Exchange (ETDEWEB)

NONE

2011-07-01

The purpose of this summary report is to highlight energy efficiency policy action and planning in IEA member countries submited to the Energy Efficiency Working Party (EEWP) from March to September 2011.

Privacy Act System of Records: Invention Reports Submitted to the EPA, EPA-38

Science.gov (United States)

Learn about the Invention Reports Submitted to the EPA System, including who is covered in the system, the purpose of data collection, routine uses for the system's records, and other security procedures.

Evaluation of disorder predictions in CASP9

KAUST Repository

Monastyrskyy, Bohdan; Fidelis, Krzysztof; Moult, John; Tramontano, Anna; Kryshtafovych, Andriy

2011-01-01

is an important issue. CASP has been assessing the state of the art in predicting disorder regions from amino acid sequence since 2002. Here, we present the results of the evaluation of the disorder predictions submitted to CASP9. The assessment is based

Subarachnoid hemorrhage: Early evaluation and optimization of management

NARCIS (Netherlands)

Germans, M.R.

2015-01-01

A subarachnoid hemorrhage (SAH) is a life-threatening disease that was first described in the 18th century, but it took until the early 20th century until the term "spontaneous subarachnoid hemorrhage" was introduced by the English neurologist Sir Charles P. Symonds. Nowadays, the term spontaneous

48 CFR 752.219-71 - Mentor requirements and evaluation.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Mentor requirements and....219-71 Mentor requirements and evaluation. As prescribed in AIDAR 719.273-11(b), insert the following clause: Mentor Requirements and Evaluation (July 13, 2007) (a) Mentor and Protégé firms shall submit an...

77 FR 42314 - Proposed Data Collections Submitted for Public Comment and Recommendations

Science.gov (United States)

2012-07-18

... characteristics of the work environment, such as the norms, rules, and common understandings that influence employees' perceptions of the importance that the organization places on safety. NIOSH requests OMB approval...] Proposed Data Collections Submitted for Public Comment and Recommendations In compliance with the...

75 FR 33614 - Adequacy Status of the Submitted 2009 PM2.5

Science.gov (United States)

2010-06-14

... that transportation activities will not produce new air quality violations, worsen existing violations... the Submitted 2009 PM 2.5 Motor Vehicle Emission Budgets for Transportation Conformity Purposes for..., PM 2.5 nonattainment areas to be adequate for transportation conformity purposes. The transportation...

Evaluation of severity and indication for surgery in acute pancreatitis on the basis of CT in the early stage

International Nuclear Information System (INIS)

Cho, Keishouku; Nakasaku, Osamu; Kim, Jung-hyo; Hatakeyama, Gen

1985-01-01

Acute pancreatitis clinically manifests various degrees of severity. In the present study, we performed a retrospective study on 32 cases of acute pancreatitis and examined the evaluation of severity and indication for surgery in acute pancreatitis on the basis of computed tomography (CT) at the early stage (about 48 hours after onset). CT in the early stage of acute pancreatitis permits objective determination of the extent of lesion enlargement. The cases could be classified into three grades, severe, moderate, and mild, as determined by CT. It was concluded, therefore, that in the early stage CT was very useful as an indicator for emergency surgery and a helpful guide to early judgement. Emergency surgery was performed on seven of nine cases in which pancreatitis was judged to be severe on the basis of abdominal CT and clinical findings. Of the seven, four had infection in the early stage (within 48 hours after onset). Three of the four had MOF complications and died. Two of three patients without infection were relieved. The pancreatitic lesion of the cases with infection was severe as assessed via CT and the CT score was especially high. Infection in the early stage of acute pancreatitis was thus thought to be a seriouns aggravating factor. A. severe (CT score ≥ 6: surgical therapy). B. moderate (CT score = 4,5: medical therapy possible). C. mild (CT score ≤ 3: medical therapy). (author)

Fluorodeoxyglucose positron emission tomography-computed tomography in evaluation of pelvic and para-aortic nodal involvement in early stage and operable cervical cancer: comparison with surgicopathological findings

International Nuclear Information System (INIS)

Bansal, Vandana; Damania, Kaizad; Sharma, Anshu Rajnish

2011-01-01

Nodal metastases in cervical cancer have prognostic implications. Imaging is used as an adjunct to clinical staging for evaluation of nodal metastases. Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) has an advantage of superior resolution of its CT component and detecting nodal disease based on increased glycolytic activity rather than node size. But there are limited studies describing its limitations in early stage cervical cancers. We have done meta-analysis with an objective to evaluate the efficacy of FDG PET/CT and its current clinical role in early stage and operable cervical cancer. Studies in which FDG PET/CT was performed before surgery in patients with early stage cervical cancers were included for analysis. PET findings were confirmed with histopathological diagnosis rather than clinical follow-up. The current data suggest that FDG PET/CT is suboptimal in nodal staging in early stage cervical cancer

Conformal radiation therapy of localized prostate cancer: acute tolerance and early evaluation of effectiveness

International Nuclear Information System (INIS)

Zierhut, D.; Flentje, M.; Sroka-Perez, G.; Rudat, V.; Engenhart-Cabillic, R.; Wannenmacher, M.

1997-01-01

Aim: In a prospective trial early effectiveness and acute toxicity of conformal 3D-planned radiotherapy for localized prostate cancer was quantified using dose-volume-histogramms and evaluated with respect of treatment technique. Results: Eleven patients (of 32) had none, 15 mild (RTOG grade 1) and 6 moderate symptoms (RTOG grade 2, mainly diarrhoea, dysuria and polyuria). Acute complications leading to treatment interruption did not occur. In 16 patients symptoms disappeared within 6 weeks after radiotherapy. Only 2 men had symptoms which lasted longer than 3 months and were endoscopically examined. Up to now no late complications were detected. Incidence and severity of toxicity was significantly (p [de

EVALUATION OF EARLY ISCHEMIC CHANGES IN STROKE PATIENTS TREATED WITH THROMBOLYTIC THERAPY

Directory of Open Access Journals (Sweden)

Kolevski Goran

2016-07-01

Full Text Available Introduction:The aim of this study is to evaluate early brain ischemic changes on CT scan in stroke patients in correlation with the clinical outcome, as well as to evaluate if there is prognostic and predictive features that can be used. Patients and methods: We examined 20 patients with acute ischemic stroke, from which 12 were male and 8 were female, at the age from 47 to 76 years. Results: The hyperdense medial artery (HMA sign was present in 10 (50% patients. Concerning the ASPECTS score, 5 patients (25% had normal score of 10 points, while 7 patients (35% had score of 7 points. 12 patients (60% had unfavorable outcome, while 8 patients (40% had favorable outcome. Our statistical analysis shows that age of more than 65 years, presence of 2 or more risk-factors, ASPECTS score of 7 and presence of HMA sign were all statistically significant predictors of unfavorable outcome in examined patients (p<0.05 each. The presence of the hyperdense medial artery sign was the most significant single predictor for unfavorable clinical outcome (p=0.0042, p<0.05. Conclusion:The presence of HMA sign is the most significant single predictor for unfavorable clinical outcome.

Report of the evaluation by the Ad Hoc Review Committee on Materials Science Research. In-advance evaluation in fiscal year 2002

Energy Technology Data Exchange (ETDEWEB)

NONE

2002-11-01

The Research Evaluation Committee, which consisted of 13 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Materials Science Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the adequacy of the R and D programs to be implemented for five years starting in Fiscal Year 2003 at Department of Materials Science in Tokai Research Establishment of JAERI. The Ad Hoc Review Committee consisted of eight specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from April 2002 to August 2002. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on June 5th, 2002, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on August 5th, 2002. This report describes the result of the evaluation by the Ad Hoc Review Committee on Materials Science Research. (author)

Report of the evaluation by the Ad Hoc Review Committee on Materials Science Research. In-advance evaluation in fiscal year 2002

Energy Technology Data Exchange (ETDEWEB)

NONE

2002-11-01

The Research Evaluation Committee, which consisted of 13 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Materials Science Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the adequacy of the R and D programs to be implemented for five years starting in Fiscal Year 2003 at Department of Materials Science in Tokai Research Establishment of JAERI. The Ad Hoc Review Committee consisted of eight specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from April 2002 to August 2002. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on June 5th, 2002, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on August 5th, 2002. This report describes the result of the evaluation by the Ad Hoc Review Committee on Materials Science Research. (author)

Report of the evaluation by the ad hoc review committee on radiation application research. In-advance evaluation in fiscal year 2001

International Nuclear Information System (INIS)

2001-11-01

The Research Evaluation Committee, which consisted of 13 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Radiation Application Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the adequacy of the R and D programs to be implemented for five years starting in Fiscal Year 2002 at Department of Material Development, at Department of Ion-Beam-Applied Biology and at Advanced Radiation Technology Center in Takasaki Radiation Chemistry Research Establishment of JAERI. The Ad Hoc Review Committee consisted of ten specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from May to July 2001. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on June 25, 2001, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on July 12, 2001. This report describes the result of the evaluation by the Ad Hoc Review Committee on Radiation Application Research. (author)

Evaluation of the observation of breast glands condition in mammographic early detection programme

International Nuclear Information System (INIS)

Kleszczewska, J.; Zomer-Drozda, J.; Tarlowska, L.; Romejko, M.

1993-01-01

The results of mammography tests were evaluated for 542 female employees of higher schools during an observation continued over 1 to 7.5 years, and they were compared with the results of the first test. Among 22 cancers detected and confirmed by macroscopic examination, mammography result turned out to be false negative in 2 cases. A positive error occurred in 7 cases. Cancer developed during observation in 8 women, that is, in 4 women from the group of 365 who earlier had correct mammography results (1.1%) and another 4 in the group of 154 women originally showing benign changes in their breast glands (2.6%). This work confirms the importance of regular checkups in the mammographic early detection programme. (author)

Teaching Evaluation Is Very Necessary at Institutions of Higher Education

Science.gov (United States)

Daren, Huang

2009-01-01

Government supervision over the quality of higher education by means of evaluations, examinations and verifications, or accreditations is a common international practice in terms of monitoring and controlling the quality of higher education. Many countries stipulate by law that institutions of higher education must submit to evaluation by the…

Evaluation of early imaging response criteria in glioblastoma multiforme

International Nuclear Information System (INIS)

Gladwish, Adam; Koh, Eng-Siew; Hoisak, Jeremy; Lockwood, Gina; Millar, Barbara-Ann; Mason, Warren; Yu, Eugene; Laperriere, Normand J; Ménard, Cynthia

2011-01-01

Early and accurate prediction of response to cancer treatment through imaging criteria is particularly important in rapidly progressive malignancies such as Glioblastoma Multiforme (GBM). We sought to assess the predictive value of structural imaging response criteria one month after concurrent chemotherapy and radiotherapy (RT) in patients with GBM. Thirty patients were enrolled from 2005 to 2007 (median follow-up 22 months). Tumor volumes were delineated at the boundary of abnormal contrast enhancement on T1-weighted images prior to and 1 month after RT. Clinical Progression [CP] occurred when clinical and/or radiological events led to a change in chemotherapy management. Early Radiologic Progression [ERP] was defined as the qualitative interpretation of radiological progression one month post-RT. Patients with ERP were determined pseudoprogressors if clinically stable for ≥6 months. Receiver-operator characteristics were calculated for RECIST and MacDonald criteria, along with alternative thresholds against 1 year CP-free survival and 2 year overall survival (OS). 13 patients (52%) were found to have ERP, of whom 5 (38.5%) were pseudoprogressors. Patients with ERP had a lower median OS (11.2 mo) than those without (not reached) (p < 0.001). True progressors fared worse than pseudoprogressors (median survival 7.2 mo vs. 19.0 mo, p < 0.001). Volume thresholds performed slightly better compared to area and diameter thresholds in ROC analysis. Responses of > 25% in volume or > 15% in area were most predictive of OS. We show that while a subjective interpretation of early radiological progression from baseline is generally associated with poor outcome, true progressors cannot be distinguished from pseudoprogressors. In contrast, the magnitude of early imaging volumetric response may be a predictive and quantitative metric of favorable outcome

Using a logic model to evaluate the Kids Together early education inclusion program for children with disabilities and additional needs.

Science.gov (United States)

Clapham, Kathleen; Manning, Claire; Williams, Kathryn; O'Brien, Ginger; Sutherland, Margaret

2017-04-01

Despite clear evidence that learning and social opportunities for children with disabilities and special needs are more effective in inclusive not segregated settings, there are few known effective inclusion programs available to children with disabilities, their families or teachers in the early years within Australia. The Kids Together program was developed to support children with disabilities/additional needs aged 0-8 years attending mainstream early learning environments. Using a key worker transdisciplinary team model, the program aligns with the individualised package approach of the National Disability Insurance Scheme (NDIS). This paper reports on the use of a logic model to underpin the process, outcomes and impact evaluation of the Kids Together program. The research team worked across 15 Early Childhood Education and Care (ECEC) centres and in home and community settings. A realist evaluation using mixed methods was undertaken to understand what works, for whom and in what contexts. The development of a logic model provided a structured way to explore how the program was implemented and achieved short, medium and long term outcomes within a complex community setting. Kids Together was shown to be a highly effective and innovative model for supporting the inclusion of children with disabilities/additional needs in a range of environments central for early childhood learning and development. The use of a logic model provided a visual representation of the Kids Together model and its component parts and enabled a theory of change to be inferred, showing how a coordinated and collaborative approached can work across multiple environments. Copyright © 2016 Elsevier Ltd. All rights reserved.

Evaluation of Histopathological Changes in Control Biopsies Which Taken 48 Sessions after NBUVB Phototherapy for Early-Stage Mycosis Fungoides

Directory of Open Access Journals (Sweden)

Ebru Zemheri

2012-01-01

Full Text Available Background. There are not many studies investigating histomorphological changes in 48 sessions in patients with early-stage MF after narrowband UVB (NBUVB treatment. Our purpose is to evaluate histological features of phototherapy after 48 sessions and determine which parameters are more reliable for controlling skin biopsies. Methods. Biopsies of 32 patients with early stage of MF, who were treated with NBUVB phototherapy, were histologically evaluated before and after the treatments, including epidermotropism, stratum corneum, epidermal thickness, dermal infiltration, papillary dermal fibrosis, vascular alterations, and other dermal changes. We discuss the histomorphological effects of NBUVB phototherapy on skin biopsies by comparing the responders with nonresponders, with before and after the treatment. Results. 9 patients (28% did not give any response to treatment. Alleviation in epidermotropism, increases in parakeratosis and normal keratosis, perivascular infiltration, and melanophages, decrease in the lichenoid/patchy lichenoid infiltration pattern after the treatment was statistically significant. Comparing by response, normalization of stratum corneum and epidermis, orthohyperkeratosis, decrease in linearly arranged cells, the lichenoid/patchy lichenoid infiltration, the loss of inflammation were statistically significant in responders group. Conclusion. We detected a significant decrease in linearly arranged cells after phototherapy, indicating that it is an “important diagnostic parameter" in evaluation of therapeutic response.

Evaluating Two Oral Health Video Interventions with Early Head Start Families

Directory of Open Access Journals (Sweden)

Lynn B. Wilson

2013-01-01

Full Text Available Poor oral health in early childhood can have long-term consequences, and parents often are unaware of the importance of preventive measures for infants and toddlers. Children in rural, low-income families suffer disproportionately from the effects of poor oral health. Participants were 91 parents of infants and toddlers enrolled in Early Head Start (EHS living in rural Hawai'i, USA. In this quasi-experimental design, EHS home visitors were assigned to use either a didactic or family-centered video with parents they served. Home visitors reviewed short segments of the assigned videos with parents over an eight-week period. Both groups showed significant prepost gains on knowledge and attitudes/behaviors relating to early oral health as well as self-reported changes in family oral health routines at a six-week followup. Controlling for pretest levels, parents in the family-centered video group showed larger changes in attitudes/behaviors at posttest and a higher number of positive changes in family oral health routines at followup. Results suggest that family-centered educational videos are a promising method for providing anticipatory guidance to parents regarding early childhood oral health. Furthermore, establishing partnerships between dental care, early childhood education, and maternal health systems offers a model that broadens potential reach with minimal cost.

Microcephaly and Zika virus: Neuroradiological aspects, clinical findings and a proposed framework for early evaluation of child development.

Science.gov (United States)

Cicuto Ferreira Rocha, Nelci Adriana; de Campos, Ana Carolina; Cicuto Ferreira Rocha, Fellipe; Pereira Dos Santos Silva, Fernanda

2017-11-01

As the recent outbreak of microcephaly cases caused by Zika virus has been declared a global health emergency, providing assessment guidelines for multidisciplinary teams providing early developmental screening and stimulation to infants with microcephaly is much needed. Thus, the aim of this manuscript is to provide an overview on what is known about neuroradiological aspects and clinical findings in infants with microcephaly caused by Zika virus and to propose a framework for early evaluation of child development. The keywords "Zika virus" and "microcephaly" were searched in PubMed database for articles published from incept to May 2017. These texts were reviewed, and the ones addressing neuroradiological and clinical findings in infants were selected. Recommendations for early assessment were made based on the International Classification of Functionality Disability and Health (ICF) model. The database search yielded 599 publications and 36 were selected. The studies detected microcephaly with diffuse brain malformations and calcifications, ventriculomegaly, optic nerve hypoplasia, macular atrophy, cataracts, impaired visual and hearing function, arthrogryposis, spasticity, hyperreflexia, irritability, tremors, and seizures, but very little is known about early development. Early assessments were described based on the ICF domains (Body Function and Structures, Activities and Participation and Contextual factors). Studies published showed abnormal brain, optic, neurologic and orthopedic findings, but very little is known about other aspects of functioning in infants with microcephaly caused by Zika virus. The biopsychosocial model based on the ICF paradigm provides an adequate framework to describe the condition of the infant with microcephaly receiving rehabilitative efforts to minimize disability. Efforts towards early identification of developmental delays should be taken within the first six months of life. Copyright © 2017 Elsevier Inc. All rights reserved.

75 FR 1790 - Proposed Data Collections Submitted for Public Comment and Recommendations

Science.gov (United States)

2010-01-13

... projected needs for training. NCHS also asks individual candidates for training to submit an application... respondents, including through the use of automated collection techniques or other forms of information... Statistics Training Application, (OMB No. 0920-0217 exp. 7/ 31/2010)--Extension--National Center for Health...

First paper from Tevatron Run II submitted by CDF collaboration

CERN Multimedia

2003-01-01

"Scientists of the Collider Detector at Fermilab submitted today (March 19) the first scientific publication of Collider Run II to the science journal Physical Review D. The paper titled "Measurement of the Mass Difference m(Ds+)-m(D+) at CDF II" summarizes the results of an analysis carried out by CDF scientists Christoph Paus and Ivan Furic, MIT, describing the mass measurement of particles containing charm quarks" (1 page).

A systematic review evaluating the role of nurses and processes for delivering early mobility interventions in the intensive care unit.

Science.gov (United States)

Krupp, Anna; Steege, Linsey; King, Barbara

2018-04-19

To investigate processes for delivering early mobility interventions in adult intensive care unit patients used in research and quality improvement studies and the role of nurses in early mobility interventions. A systematic review was conducted. Electronic databases PubMED, CINAHL, PEDro, and Cochrane were searched for studies published from 2000 to June 2017 that implemented an early mobility intervention in adult intensive care units. Included studies involved progression to ambulation as a component of the intervention, included the role of the nurse in preparing for or delivering the intervention, and reported at least one patient or organisational outcome measure. The System Engineering Initiative for Patient Safety (SEIPS) model, a framework for understanding structure, processes, and healthcare outcomes, was used to evaluate studies. 25 studies were included in the final review. Studies consisted of randomised control trials, prospective, retrospective, or mixed designs. A range of processes to support the delivery of early mobility were found. These processes include forming interdisciplinary teams, increasing mobility staff, mobility protocols, interdisciplinary education, champions, communication, and feedback. Variation exists in the process of delivering early mobility in the intensive care unit. In particular, further rigorous studies are needed to better understand the role of nurses in implementing early mobility to maintain a patient's functional status. Copyright © 2018 Elsevier Ltd. All rights reserved.

Evaluating the Use of Remote Sensing Data in the USAID Famine Early Warning Systems Network

Science.gov (United States)

Brown, Molly E.; Brickley, Elizabeth B.

2011-01-01

The US Agency for International Development (USAID) s Famine Early Warning System Network (FEWS NET) provides monitoring and early warning support to decision makers responsible for responding to food insecurity emergencies on three continents. FEWS NET uses satellite remote sensing and ground observations of rainfall and vegetation in order to provide information on drought, floods and other extreme weather events to decision makers. Previous research has presented results from a professional review questionnaire with FEWS NET expert end-users whose focus was to elicit Earth observation requirements. The review provided FEWS NET operational requirements and assessed the usefulness of additional remote sensing data. Here we analyzed 1342 food security update reports from FEWS NET. The reports consider the biophysical, socioeconomic, and contextual influences on the food security in 17 countries in Africa from 2000-2009. The objective was to evaluate the use of remote sensing information in comparison with other important factors in the evaluation of food security crises. The results show that all 17 countries use rainfall information, agricultural production statistics, food prices and food access parameters in their analysis of food security problems. The reports display large scale patterns that are strongly related to history of the FEWS NET program in each country. We found that rainfall data was used 84% of the time, remote sensing of vegetation 28% of the time, and gridded crop models 10%, reflecting the length of use of each product in the regions. More investment is needed in training personnel on remote sensing products to improve use of data products throughout the FEWS NET system.

Clinical profile and response to treatment of patients with pituitary adenomas submitted to radiotherapy

International Nuclear Information System (INIS)

Moraes, Paulo Lazaro de; Freire, Geison Moreira; Dias, Rodrigo Souza; Segreto, Roberto Araujo; Segreto, Helena Regina Comodo; Abucham Filho, Julio Zaki

2008-01-01

Objective: to evaluate the clinical profile of patients with pituitary adenoma and their response to radiotherapy. Material and method: retrospective study with 22 patients with diagnosis of pituitary adenoma which were submitted to radiotherapy between March 2004 and December 2008. Patients' characteristics such as gender, age, clinical presentation, surgical approach, immunohistochemistry profile, dose of radiation and the response to therapy were analyzed using hormonal dosages and imaging exams. Results: the median age was 51 years and equally distributed in both genders. The tumors were divided according to the Hardy's classification: 27.5% had grade II, 27.5% had grade III and 45% had grade IV. The main symptoms presented by patients at diagnosis were visual impairment in 77% of cases, headache in 68%, amenorrhea and acromegaly in 27% and galactorrhoea in 4.5%. Transphenoidal surgery was performed in 21 patients and only 1 patient was submitted to transcranial approach; 91% of cases had partial resection. Concerning to immunohistochemistry, the expression of ACTH was the most frequent, being present in 41% of cases. The patients were treated in megavoltage equipment mostly with 6 MV linear accelerator. The total radiation dose was 45 Gy in 68% of patients and a dose of 50.4 Gy in 13% of cases. Three-dimensional planning was used in 20 patients. The median follow-up was 41 months. Laboratory and imaging improvement were observed in 73% of patients, stability in 22.5%, and worsening in 4.5%. Conclusion: the results show good rates of response and control of pituitary adenomas by radiation in the first four years after treatment. Considering it has a slow response to treatment, there is a high chance of improvement in results later during the follow-up. (author)

Evaluation of bone repair in the femur of rats submitted to laser therapy in different wavelengths: An image segmentation method of analysis

Science.gov (United States)

Queiroga, A. S.; Sousa, F. B.; Araújo, J. M. S.; Santos, S. D.; Sousa, C. D'f. S.; Quintans, T. C.; Almeida, T. P.; Nonaka, C. F. W.; Batista, L. V.; Limeira Junior, F. A.

2008-09-01

The aim of this study was to histologically assess the effect of laser therapy (LILT, 660 and 780 nm) on the repair of standardized bone defects on the femur of Wistar albinus rats. The sample was composed of 12 Wistar albinus young adult rats of both genders. Three randomized groups were studied: group I (control, n = 4), group II (LILT, 660 nm, n = 4), and group III (LILT, 780 nm, n = 4). Samples were prepared using a bone defect on the left-side femur surface of the animals, with a total dimension of approximately 3 mm3. Groups II and III were irradiated every 48 h from the second application, where the first dose was given immediately after surgery and the second application came 24 h after surgery. The irradiations were applied transcutaneously at four points around the wound for 14 days. At each point, a dose of 50 J/cm2 (2 J) was given ( s ˜ 0.04 cm2, 40 mW) and the total dose per session was 200 J/cm2 (8 J). The sacrifices were made 15 days after surgery and the specimens were routinely processed to wax, serially cut, stained with an H&E stain, and analyzed under light microscopy. The images were submitted to morphometric analysis using the image segmentation method using the K-means algorithm. The data obtained through the morphometric analysis were submitted to statistical analysis using the Tukey test. The results showed that the group treated with laser therapy in the infrared spectrum resulted in an increase in the repair of bone defects when compared with the group treated with the laser in the red spectrum and control group, which, in turn, had a very similar pattern of repair. A statistical significance ( p spectrum produced a positive biomodulation effect on the repair of bone defects in the femur of rats.

Sustainability Evaluation of Retrofitting and Renovation of Buildings in Early Stages

DEFF Research Database (Denmark)

Jensen, Per Anker; Maslesa, Esmir; Gohardani, Navid

2013-01-01

research results and ideas for the development of a tool, which can be used as decision support for renovation projects in early stages. The research is part of the Eracobuild project ACES – “A concept for promotion of sustainable retrofitting and renovation in early stages” with participants from Denmark...

Report of the evaluation by the Ad Hoc Review Committee on High-Temperature Engineering and Research. Result evaluation in fiscal year 2000

International Nuclear Information System (INIS)

2001-06-01

The Research Evaluation Committee, which consisted of 14 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on High-Temperature Engineering and Research in accordance with the 'Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the R and D accomplishments achieved for five years from Fiscal Year 1995 to Fiscal Year 1999 at Department of HTTR Project and Department of Advanced Nuclear Heat Technology in Oarai Research Establishment of JAERI. The Ad Hoc Review Committee consisted of nine specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from December 2000 to February 2001. The evaluation was performed on the basis of the materials submitted in advanced and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on December 8, 2000, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on March 16, 2001. This report describes the result of the evaluation by the Ad Hoc Review Committee on High-Temperature Engineering and Research. (author)

Clinical role of early dynamic FDG-PET/CT for the evaluation of renal cell carcinoma.

Science.gov (United States)

Nakajima, Reiko; Abe, Koichiro; Kondo, Tsunenori; Tanabe, Kazunari; Sakai, Shuji

2016-06-01

We studied the usefulness of early dynamic (ED) and whole-body (WB) FDG-PET/CT for the evaluation of renal cell carcinoma (RCC). One hundred patients with 107 tumours underwent kidney ED and WB FDG-PET/CT. We visually and semiquantitatively evaluated the FDG accumulation in RCCs in the ED and WB phases, and compared the accumulation values with regard to histological type (clear cell carcinoma [CCC] vs. non-clear cell carcinoma [N-CCC]), the TNM stage (high stage [3-4] vs. low stage [1-2]), the Fuhrman grade (high grade [3-4] vs. low grade [1-2]) and presence versus absence of venous (V) and lymphatic (Ly) invasion. In the ED phase, visual evaluation revealed no significant differences in FDG accumulation in terms of each item. However, the maximum standardized uptake value and tumour-to-normal tissue ratios were significantly higher in the CCCs compared to the N-CCCs (p PET/CT is a useful tool for the evaluation of RCCs. • ED and WB FDG-PET/ CT helps to assess patients with RCC • ED FDG-PET/CT enabled differentiation between CCC and N-CCC • FDG accumulation in the WB phase reflects tumour aggressiveness • Management of RCC is improved by ED and WB FDG-PET/CT.

41 CFR 301-52.7 - When must I submit my travel claim?

Science.gov (United States)

2010-07-01

... travel claim? 301-52.7 Section 301-52.7 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES ARRANGING FOR TRAVEL SERVICES, PAYING TRAVEL EXPENSES, AND CLAIMING REIMBURSEMENT 52-CLAIMING REIMBURSEMENT § 301-52.7 When must I submit my travel...

76 FR 28192 - Petition for Rulemaking Submitted by the Nuclear Energy Institute

Science.gov (United States)

2011-05-16

... NUCLEAR REGULATORY COMMISSION 10 CFR Part 26 [Docket No. PRM-26-5; NRC-2010-0304] Petition for Rulemaking Submitted by the Nuclear Energy Institute AGENCY: Nuclear Regulatory Commission. ACTION: Petition... Anthony R. Pietrangelo, on behalf of the Nuclear Energy Institute (NEI), the petitioner, in the planned...

15 CFR 711.7 - Where to submit declarations, reports and advance notifications.

Science.gov (United States)

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Where to submit declarations, reports and advance notifications. 711.7 Section 711.7 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL...

17 CFR 1.54 - Contract market rules submitted to and approved or not disapproved by the Secretary of Agriculture.

Science.gov (United States)

2010-04-01

... submitted to and approved or not disapproved by the Secretary of Agriculture. 1.54 Section 1.54 Commodity... Secretary of Agriculture. Notwithstanding any provision of these rules, any bylaw, rule, regulation, or resolution of a contract market that was submitted to the Secretary of Agriculture pursuant or § 1.38(a) or...

The pilot evaluation for the National Evaluation System in South Africa – A diagnostic review of early childhood development

Directory of Open Access Journals (Sweden)

Margot Davids

2015-10-01

Full Text Available Policymaking in many instances does not follow proper diagnosis of a problem using evidence to justify why particular decisions have been taken. This article describes findings of a diagnostic review of existing challenges facing early childhood development (ECD in South Africa. The review is part of the government’s attempt to use information to drive policy in strategic areas. It is part of the role that the Presidency is seeking to play in ensuring government programmes are evaluated to ensure that money that is spent is spent on programmes that have an impact and that there is value for money. This article summarises the key findings of the diagnostic review that was conducted of policy, services and coordination.The results reveal that a broader definition of ECD programmes is needed to cover all aspects of children’s development, growth and health, from conception to the foundation phase of schooling. Many elements of comprehensive ECD support and services are already in place and some are performing well. However, there are important gaps. Key ECD strategies for the future are identified. The diagnostic evaluation used a variety of methods, including desktop analysis, interviews and data analysis. Issues emerged around how to link the evaluation with other processes in the involved departments. A particular challenge was how to handle the transition to implementation of the findings, as responsibility shifted from the steering committee to the departments. The process worked well despite past challenges with coordination across government.

DIMENSIONAL BEHAVIOR OF THE WOOD OF SAPWOOD AND HEARTWOOD FOR ANALYSIS OF IMAGE SUBMITTED IN DIFFERENT TEMPERATURES

Directory of Open Access Journals (Sweden)

Dimas Agostinho da Silva

2003-01-01

Full Text Available The objective of this work was to verify the dimensional behavior of heartwood woodand sapwood submitted to different temperatures. It was evaluated volumetric, sectional and lineardimension reduction in heartwood and sapwood of Hymeneae courbaril L submitted to finaltemperatures of 200º, 300º, 400º, 500º, 600º, 700º, 800º and 900°C, in an electric kiln with mediumrate of heating of 1.3ºC/minute. For the measurement of the dimensions, accomplished before andafter the thermal treatments, an image analyzer (Midro-Videomat Zeiss was used. It was obtained,with base in the individual readings accomplished in the image analyzer, the rates of longitudinal andtraverse linear, longitudinal and traverse sectional and volumetric reduction. The results showed thattem- perature increase of 1000C, average reduction rate reached 2.55% and 4.24%, 5.95% and 7.21% and 8.36% in the longitudinal and traverse linear dimensions, longitudinal and traverse sectional andvolumetric, respectively, for heartwood. For sapwood the values were, respectively, 2.64% and 5.02%,6.70% and 8.17% and 9.15%. For both sapwood and heartwood the largest reduction rates occurredin temperatures between 300º and 5000C. The heartwood presented larger resistance to the action ofthe temperature, however its thermal decomposition was more pronounced than that of sapwood inthe temperature range of 200-300 0C. This behavior is similar to that of lignin in relation to cellulose.

Early evaluation of patient risk for substantial weight gain during olanzapine treatment for schizophrenia, schizophreniform, or schizoaffective disorder

Directory of Open Access Journals (Sweden)

Hardy Thomas A

2008-09-01

Full Text Available Abstract Background To make well informed treatment decisions for their patients, clinicians need credible information about potential risk for substantial weight gain. We therefore conducted a post-hoc analysis of clinical trial data, examining early weight gain as a predictor of later substantial weight gain. Methods Data from 669 (Study 1 and 102 (Study 2 olanzapine-treated patients diagnosed with schizophrenia, schizophreniform, or schizoaffective disorder were analyzed to identify and validate weight gain cut-offs at Weeks 1–4 that were predictive of substantial weight gain (defined as an increase of ≥ 5, 7, 10 kg or 7% of baseline weight after approximately 30 weeks of treatment. Baseline characteristics alone, baseline characteristics plus weight change from baseline to Weeks 1, 2, 3 or 4, and weight change from baseline to Weeks 1, 2, 3, or 4 alone were evaluated as predictors of substantial weight gain. Similar analyses were performed to determine BMI increase cut-offs at Weeks 1–4 of treatment that were predictive of substantial increase in BMI (1, 2 or 3 kg/m2 increase from baseline. Results At Weeks 1 and 2, predictions based on early weight gain plus baseline characteristics were more robust than those based on early weight gain alone. However, by Weeks 3 and 4, there was little difference between the operating characteristics associated with these two sets of predictors. The positive predictive values ranged from 30.1% to 73.5%, while the negative predictive values ranged from 58.1% to 89.0%. Predictions based on early BMI increase plus baseline characteristics were not uniformly more robust at any time compared to those based on early BMI increase alone. The positive predictive values ranged from 38.3% to 83.5%, while negative predictive values ranged from 42.1% to 84.7%. For analyses of both early weight gain and early BMI increase, results for the validation dataset were similar to those observed in the primary dataset

Bone-Implant Contact around Crestal and Subcrestal Dental Implants Submitted to Immediate and Conventional Loading

Directory of Open Access Journals (Sweden)

Ana Emília Farias Pontes

2014-01-01

Full Text Available The present study aims to evaluate the influence of apicocoronal position and immediate and conventional loading in the percentage of bone-implant contact (BIC. Thus, 36 implants were inserted in the edentulous mandible from six dogs. Three implants were installed in each hemimandible, in different positions in relation to the ridge: Bone Level (at crestal bone level, Minus 1 (one millimeter apical to crestal bone, and Minus 2 (two millimeters apical to crestal bone. In addition, each hemimandible was submitted to a loading protocol: immediate (prosthesis installed 24 hours after implantation or conventional (prosthesis installed 120 days after implantation. Ninety days after, animals were killed, and implant and adjacent tissues were prepared for histometric analysis. BIC values from immediate loaded implants were 58.7%, 57.7%, and 51.1%, respectively, while conventional loaded implants were 61.8%, 53.8%, and 68.4%. Differences statistically significant were not observed among groups (P=0.10, ANOVA test. These findings suggest that different apicocoronal positioning and loading protocols evaluated did not interfere in the percentage of bone-implant contact, suggesting that these procedures did not jeopardize osseointegration.

Evaluated neutronic file for indium

International Nuclear Information System (INIS)

Smith, A.B.; Chiba, S.; Smith, D.L.; Meadows, J.W.; Guenther, P.T.; Lawson, R.D.; Howerton, R.J.

1990-01-01

A comprehensive evaluated neutronic data file for elemental indium is documented. This file, extending from 10 -5 eV to 20 MeV, is presented in the ENDF/B-VI format, and contains all neutron-induced processes necessary for the vast majority of neutronic applications. In addition, an evaluation of the 115 In(n,n') 116m In dosimetry reaction is presented as a separate file. Attention is given in quantitative values, with corresponding uncertainty information. These files have been submitted for consideration as a part of the ENDF/B-VI national evaluated-file system. 144 refs., 10 figs., 4 tabs

Report of the evaluation by the Ad Hoc Review Committee on Nuclear Safety Research. Result evaluation in fiscal year 2000

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-06-01

The Research Evaluation Committee, which consisted of 14 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Nuclear Safety Research in accordance with the Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the R and D accomplishments achieved for five years from Fiscal Year 1995 to Fiscal Year 1999 at Department of Reactor Safety Research, Department of Fuel Cycle Safety Research, Department of Environmental Safety Research and Department of Safety Research Technical Support in Tokai Research Establishment at JAERI. The Ad Hoc Review Committee consisted of 11 specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from December 2000 to February 2001. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on December 11, 2000, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on March 16, 2001. This report describes the result of the evaluation by the Ad Hoc Review Committee on Nuclear Safety Research. (author)

Weight gain in newborns submitted to skin-to-skin contact

Directory of Open Access Journals (Sweden)

Ana Karine da Costa Monteiro Souza

Full Text Available ABSTRACT Purpose: to compare the weight gain among newborns submitted to the kangaroo method and those not submitted to it, and to analyze the factors that may influence this gain: length of hospital stay, gestational age, corrected gestational age, birth weight, weight on the first day of follow-up, duration of gastric tube feeding, duration of oral feeding, and type of diet. Methods: a cross-sectional, quantitative study, with 86 newborns divided into two groups: group 1, with 48 neonates undergoing skin-to-skin contact and Group 2, 38 newborns who did not have this contact. Weights were recorded until hospital discharge. Results: a greater weight gain in Group 1, a longer time of hospitalization in Group 2, and a significant difference in weight gain related to the type of diet in Group 2. Conclusion: skin-to-skin contact has a positive influence on weight gain and length of hospital stay of newborns. The use of an infant formula does not influence weight gain for dyads who experienced skin-to-skin contact. Gestational age, corrected gestational age, birth weight, weight on the first day of follow-up, duration of gastric tube feeding, duration of oral feeding are not correlated with weight gain.

77 FR 70828 - Proposed Extension of Information Collection Requests Submitted for Public Comment

Science.gov (United States)

2012-11-27

... DEPARTMENT OF LABOR Employee Benefits Security Administration Proposed Extension of Information Collection Requests Submitted for Public Comment AGENCY: Employee Benefits Security Administration... collection requirements and provide the requested data in the desired format. The Employee Benefits Security...

78 FR 30333 - Proposed Extension of Information Collection Requests Submitted for Public Comment

Science.gov (United States)

2013-05-22

... DEPARTMENT OF LABOR Employee Benefits Security Administration Proposed Extension of Information Collection Requests Submitted for Public Comment AGENCY: Employee Benefits Security Administration... collection requirements and provide the requested data in the desired format. The Employee Benefits Security...

Early Childhood Development and E-Learning in Africa: The Early Childhood Development Virtual University Programme

Science.gov (United States)

Pence, Alan

2007-01-01

This article explores the development and evaluation of the graduate-level Early Childhood Development Virtual University (ECDVU) programme in Sub-Saharan Africa from 2001 through to 2004. It outlines the history of the ECDVU and the establishing of a Sub-Saharan programme for future leaders in the early childhood field guided by the key principle…

[Evaluation of quality of service in Early Intervention: A systematic review].

Science.gov (United States)

Jemes Campaña, Inmaculada Concepción; Romero-Galisteo, Rita Pilar; Labajos Manzanares, María Teresa; Moreno Morales, Noelia

2018-06-07

Early Intervention (EI), as a paediatric service, has the duty of quantifying the results and the quality of its services provided. The accessibility of valid and reliable tools allows professionals to evaluate the quality of these services. The aim of this study is to review the scientific literature on tools used to measure the methodological and service quality in EI. A search was made in different databases: Medline (from PubMed), Web of Science, PsycINFO, Cochrane, Scopus, ERIC and Scielo. The methodological quality of the studies was tested using the COSMIN scale. A total of 13 manuscripts met the criteria to be included in this review. Ten of them received a "good" or "reasonable" score based on the COSMIN scale. Despite its importance, there is no consensus among authors on the measurement of service quality in EI. It is often the family of the children attended in EI that are considered the target to study, although the opinion of professionals carries more weight and completes the information. Copyright © 2018. Publicado por Elsevier España, S.L.U.

Evaluation of KFB-funded research on transport systems

Energy Technology Data Exchange (ETDEWEB)

Boyce, D.; Knudsen, T.; Wegener, M.

1999-09-01

This report presents an evaluation of two research projects on transport systems, which have been financed fully or partially by KFB. The projects are: l. Systems analysis of transport markets at the Division of Transport and Location Analysis in the Department of Infrastructure and Planning of the Royal Institute of Technology, Stockholm; and 2. Planning, analysis and management in traffic networks - optimization models and methods at the Division of Optimization in the Department of Mathematics at Linkoeping University. The evaluation seeks to examine the scientific quality of the research and its relevance to the academic world and society. The two project teams prepared a self-assessment of their research activities and submitted copies of relevant publications. The evaluation committee visited both institutions and engaged the teams in discussions of their results and methodology. These visits occurred on June 1 and 2, 1999. This report is based on the self-assessments of the teams, the materials submitted and the meetings with the project teams. The evaluation and recommendations presented in the report are those of the reviewers and do not necessarily represent the views of KFB

34 CFR 35.4 - Administrative claim; evidence and information to be submitted.

Science.gov (United States)

2010-07-01

... the interval between injury and death. (8) Any other evidence or information which may have a bearing...) Death. In support of a claim based on death, the claimant may be required to submit the following evidence or information: (1) An authenticated death certificate or other competent evidence showing cause...

75 FR 80861 - Agency Forms Submitted for OMB Review, Request for Comments

Science.gov (United States)

2010-12-23

... collection techniques or other forms of information technology. Comments to RRB or OIRA must contain the OMB..., information needed to ensure secure system access from employers who voluntarily opt to use the RRB's Internet... (RRB) is submitting five (5) Information Collection Requests (ICR) to the Office of Information and...

40 CFR 355.21 - In what format should the information be submitted?

Science.gov (United States)

2010-07-01

... (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS EMERGENCY PLANNING AND NOTIFICATION Emergency Planning How to Comply § 355.21 In what format should the information be submitted? EPA... 40 Protection of Environment 27 2010-07-01 2010-07-01 false In what format should the information...

21 CFR 803.32 - If I am a user facility, what information must I submit in my individual adverse event reports?

Science.gov (United States)

2010-04-01

... elements of FDA Form 3500A: (a) Patient information (Form 3500A, Block A). You must submit the following...) Device information (Form 3500A, Block D). You must submit the following: (1) Brand name; (2) Type of...

The procedures used to review safety analysis reports for packagings submitted to the US Department of Energy for certification

International Nuclear Information System (INIS)

Popper, G.F.; Raske, D.T.; Turula, P.

1988-01-01

This paper presents an overview of the procedures used at the Argonne National Laboratory (ANL) to review Safety Analysis Reports for Packagings (SARPs) submitted to the US Department of Energy (DOE) for issuance of a Certificate of Compliance. Prior to certification and shipment of a packaging for the transport of radioactive materials, a SARP must be prepared describing the design, contents, analyses, testing, and safety features of the packaging. The SARP must be reviewed to ensure that the specific packaging meets all DOE orders and federal regulations for safe transport. The ANL SARP review group provides an independent review and evaluation function for the DOE to ensure that the packaging meets all the prescribed requirements. This review involves many disciplines and includes evaluating the general information, drawings, construction details, operating procedures, maintenance and test programs, and the quality assurance plan for compliance with requirements. 14 refs., 6 figs

Quantitative Evaluation of Tumor Early Response to a Vascular-Disrupting Agent with Dynamic PET.

Science.gov (United States)

Guo, Ning; Zhang, Fan; Zhang, Xiaomeng; Guo, Jinxia; Lang, Lixin; Kiesewetter, Dale O; Niu, Gang; Li, Quanzheng; Chen, Xiaoyuan

2015-12-01

The purpose of this study is to evaluate the early response of tumors to a vascular-disrupting agent (VDA) VEGF121/recombinant toxin gelonin (rGel) using dynamic [(18)F]FPPRGD2 positron emission tomography (PET) and kinetic parameter estimation. Two tumor xenograft models: U87MG (highly vascularized) and A549 (moderately vascularized), were selected, and both were randomized into treatment and control groups. Sixty-minute dynamic PET scans with [(18)F]FPPRGD2 that targets to integrin αvβ3 were performed at days 0 (baseline), 1, and 3 since VEGF121/rGel treatment started. Dynamic PET-derived binding potential (BPND) and parametric maps were compared with tumor uptake (%ID/g) and the static PET image at 1 h after the tracer administration. The growth of U87MG tumor was obviously delayed upon VEGF121/rGel treatment. A549 tumor was not responsive to the same treatment. BPND of treated U87MG tumors decreased significantly at day 1 (p dynamic PET with [(18)F]FPPRGD2 shows advantages in distinguishing effective from ineffective treatment during the course of VEGF121/rGel therapy at early stage and is therefore more sensitive in assessing therapy response than static PET.

Stability of fault submitted to fluid injections

Science.gov (United States)

Brantut, N.; Passelegue, F. X.; Mitchell, T. M.

2017-12-01

Elevated pore pressure can lead to slip reactivation on pre-existing fractures and faults when the coulomb failure point is reached. From a static point of view, the reactivation of fault submitted to a background stress (τ0) is a function of the peak strength of the fault, i.e. the quasi-static effective friction coefficient (µeff). However, this theory is valid only when the entire fault is affected by fluid pressure, which is not the case in nature, and during human induced-seismicity. In this study, we present new results about the influence of the injection rate on the stability of faults. Experiments were conducted on a saw-cut sample of westerly granite. The experimental fault was 8 cm length. Injections were conducted through a 2 mm diameter hole reaching the fault surface. Experiments were conducted at four different order magnitudes fluid pressure injection rates (from 1 MPa/minute to 1 GPa/minute), in a fault system submitted to 50 and 100 MPa confining pressure. Our results show that the peak fluid pressure leading to slip depends on injection rate. The faster the injection rate, the larger the peak fluid pressure leading to instability. Wave velocity surveys across the fault highlighted that decreasing the injection-rate leads to an increase of size of the fluid pressure perturbation. Our result demonstrate that the stability of the fault is not only a function of the fluid pressure requires to reach the failure criterion, but is mainly a function of the ratio between the length of the fault affected by fluid pressure and the total fault length. In addition, we show that the slip rate increases with the background effective stress and with the intensity of the fluid pressure pertubation, i.e. with the excess shear stress acting on the part of the fault pertubated by fluid injection. Our results suggest that crustal fault can be reactivated by local high fluid overpressures. These results could explain the "large" magnitude human-induced earthquakes

Fetal dose determination in patients with breast cancer submitted to radiotherapy

International Nuclear Information System (INIS)

Melo, H.C.; Roesler, I.C.; Leon, E.

1985-01-01

The exposure that the fetus receive during radiotherapy treatment for patients with breast cancer submitted to cobalt 60 and linear accelerator of 6 MV is studied. Measurements with a rando-Alderson Phantom and ionization chamber for each individualized irradiation field, at the body level where the fetus is localized during the several stages of pregnancy, are made. (M.A.C.) [pt

24 CFR 266.115 - Program monitoring and evaluation.

Science.gov (United States)

2010-04-01

... AUTHORITIES HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Housing Finance Agency Requirements § 266.115 Program monitoring and evaluation. (a) HFA certifications... under this part, basic underwriting and closing information must be submitted in a format specified by...

14 CFR 120.11 - Refusal to submit to a drug or alcohol test by a Part 61 certificate holder.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Refusal to submit to a drug or alcohol test...: CERTIFICATION AND OPERATIONS DRUG AND ALCOHOL TESTING PROGRAM Individuals Certificated Under Parts 61, 63, and 65 § 120.11 Refusal to submit to a drug or alcohol test by a Part 61 certificate holder. (a) This...

14 CFR 120.15 - Refusal to submit to a drug or alcohol test by a Part 65 certificate holder.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Refusal to submit to a drug or alcohol test...: CERTIFICATION AND OPERATIONS DRUG AND ALCOHOL TESTING PROGRAM Individuals Certificated Under Parts 61, 63, and 65 § 120.15 Refusal to submit to a drug or alcohol test by a Part 65 certificate holder. (a) This...

14 CFR 120.13 - Refusal to submit to a drug or alcohol test by a Part 63 certificate holder.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Refusal to submit to a drug or alcohol test...: CERTIFICATION AND OPERATIONS DRUG AND ALCOHOL TESTING PROGRAM Individuals Certificated Under Parts 61, 63, and 65 § 120.13 Refusal to submit to a drug or alcohol test by a Part 63 certificate holder. (a) This...

Quality of life in patients submitted to radical prostatectomy

OpenAIRE

Débora Moura Miranda Goluart; Mário Alfredo Silveira Miranzi; Paulo Eduardo Nunes Goulart

2014-01-01

A cross-sectional study with a descriptive analysis of 81 patients submitted to radical prostatectomy (RP). Our objective was to correlate quality of life (QL) according to the EORTC-QLQ C30 with age group and time after surgery. Mean age was 65.7 years. Most sought the care of urology, asymptomatic. Some referred former smoking (49.9%) and high blood pressure (53.1%). Mean preoperative SBP was 8.4 ng/ml. Most participants were in stages T2c to T3, Gleason ?6 and over a year after surgery. Er...

Clinical Evaluation of Brain Perfusion SPECT with Brodmann Areas Mapping in Early Diagnosis of Alzheimer's Disease.

Science.gov (United States)

Valotassiou, Varvara; Papatriantafyllou, John; Sifakis, Nikolaos; Tzavara, Chara; Tsougos, Ioannis; Psimadas, Dimitrios; Fezoulidis, Ioannis; Kapsalaki, Eftychia; Hadjigeorgiou, George; Georgoulias, Panagiotis

2015-01-01

Early diagnosis of Alzheimer's disease (AD) based on clinical criteria alone may be problematic, while current and future treatments should be administered earlier in order to be more effective. Thus, various disease biomarkers could be used for early detection of AD. We evaluated brain perfusion with 99mTc-HMPAO single photon emission computed tomography (SPECT) and Brodmann areas (BAs) mapping in mild AD using an automated software (NeuroGam) for the semi-quantitative evaluation of perfusion in BAs and the comparison with the software's normal database. We studied 34 consecutive patients with mild AD: 9 men, 25 women, mean age 70.9 ± 8.1 years, mean Mini-Mental State Examination 22.6 ± 2.5. BAs 25L, 25R, 38L, 38R, 28L, 28R, 36L, and 36R had the lower mean perfusion values, while BAs 31L, 31R, 19R, 18L, 18R, 17L, and 17R had the higher mean values. Compared with healthy subjects of the same age, perfusion values in BAs 25L, 25R, 28R, 28L, 36L, and 36R had the greatest deviations from the healthy sample, while the lowest deviations were found in BAs 32L, 32R, 19R, 24L, 17L, 17R, 18L, and 18R. A percentage of ≥94% of patients had perfusion values more than -2SDs below the mean of healthy subjects in BAs 38R, 38L, 36L, 36R, 23L, 23R, 22L, 44L, 28L, 28R, 25L, and 25R. The corresponding proportion was less than 38% for BAs 11L, 19R, 32L, 32R, 18L, 18R, 24L, and 17R. In conclusion, brain SPECT studies with automated perfusion mapping could be useful as an ancillary tool in daily practice, revealing perfusion impairments in early AD.

Scientific writing seminar for early-stage investigators in substance abuse research.

Science.gov (United States)

Guydish, Joseph; Masson, Carmen; Flentje, Annesa; Shopshire, Michael; Sorensen, James L

2016-01-01

There is little information on how to increase the scientific writing productivity of early-stage investigators in the addictions field. A scientific writing seminar is presented in this article, aiming to encourage manuscript writing and dissemination of addiction research, and outcomes are reported for 14 years of the seminar. In 14 years, there were 113 postdoctoral fellow enrollments in a 6-month writing seminar. Records of submission and publication rates of manuscripts were collected for 14 cohorts. Of the 113 participant enrollments, 97 (86%) submitted a manuscript for publication, and 87 participants (77%) published their manuscript. A scientific writing seminar may benefit writing productivity, but more research is needed to compare this training model with other existing models.

The Maritime Declaration of Health (MDH) as a tool to detect maritime traffic-related health risks: analysis of MDH forms submitted to Spanish ports, October 2014 to March 2015.

Science.gov (United States)

López-Gigosos, Rosa M; Segura, Marina; Díez-Díaz, Rosa M; Ureña, Isabel; Urzay, David; Guillot, Patricia; Guerra-Neira, Ana; Rivera, Almudena; Pérez-Cobaleda, Ángeles; Martín, Ascensión; Nuñez-Torrón, María; Alvarez, Begoña; Faraco, Mar; Barrera, José M; Calvo, María J; Gallegos, José; Bermejo, Antonio; Aramburu, Carmen; Dávila, Miguel; Carreras, Fernando; Neipp, Rosemarie; Mariscal, Alberto

2017-06-15

The international maritime traffic of people and goods has often contributed to the spread of pathogens affecting public health. The Maritime Declaration of Health (MDH), according to the International Health Regulations (IHR) (2005), is a document containing data related to the state of health on board a ship during passage and on arrival at port. It is a useful tool for early detection of public health risks. The main objective of our study was to evaluate compliance with the model provided in the IHR, focusing on the format and degree of completion of MDH forms received at Spanish ports. We reviewed the content of 802 MDH forms submitted to nine Spanish ports between October 2014 and March 2015. Study results show that 22% of MDH forms presented did not comply with the recommended model and 39% were incomplete. The proportion of cargo ships with correct and complete MDH forms was lower than passenger ships; thus, the nine health questions were answered less frequently by cargo ships than passenger ships (63% vs 90%, p value < 0.001). The appropriate demand and usage of MDH forms by competent authorities should improve the quality of the document as a tool and improve risk assessment. This article is copyright of The Authors, 2017.

Preliminary Evaluation of a Social Skills Training and Facilitated Play Early Intervention Programme for Extremely Shy Young Children in China

Science.gov (United States)

Li, Yan; Coplan, Robert J.; Wang, Yuemin; Yin, Jingtong; Zhu, Jingjing; Gao, Zhuqing; Li, Linhui

2016-01-01

The goal of this study was to provide a preliminary evaluation of a social skills and facilitated play early intervention programme to promote social interaction, prosocial behaviours and socio-communicative skills among young extremely shy children in China. Participants were a sample of n = 16 extremely shy young children attending kindergarten…

Evaluation of residue-residue contact predictions in CASP9

KAUST Repository

Monastyrskyy, Bohdan; Fidelis, Krzysztof; Tramontano, Anna; Kryshtafovych, Andriy

2011-01-01

This work presents the results of the assessment of the intramolecular residue-residue contact predictions submitted to CASP9. The methodology for the assessment does not differ from that used in previous CASPs, with two basic evaluation measures

New treatment of early fetal chylothorax

DEFF Research Database (Denmark)

Nygaard, Ulrikka; Sundberg, Karin; Nielsen, Henriette Svarre

2007-01-01

OBJECTIVE: To evaluate OK-432, a preparation of Streptococcus pyogenes, in the treatment of early fetal chylothorax. METHODS: A prospective study of all fetuses (n=7) with persistent early chylothorax (gestational ages 16-21 weeks) referred to the tertiary center of fetal medicine in Denmark in 2...

21 CFR 1.402 - What are the requirements for submitting an appeal?

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false What are the requirements for submitting an appeal? 1.402 Section 1.402 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL GENERAL ENFORCEMENT REGULATIONS Administrative Detention of Food for Human or Animal...

41 CFR 301-52.6 - How do I submit a travel claim?

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false How do I submit a travel claim? 301-52.6 Section 301-52.6 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES ARRANGING FOR TRAVEL SERVICES, PAYING TRAVEL EXPENSES, AND...

77 FR 5858 - Agency Forms Submitted for OMB Review, Request for Comments

Science.gov (United States)

2012-02-06

... Regulatory Affairs (OIRA), Office of Management and Budget (OMB). Our ICR describes the information we seek... requiring an applicant to submit documentary evidence of marriage are prescribed in 20 CFR 219.30. In the absence of documentary evidence, the RRB needs to determine if a valid marriage existed between a spouse...

78 FR 18633 - Agency Forms Submitted for OMB Review, Request for Comments

Science.gov (United States)

2013-03-27

... Affairs (OIRA), Office of Management and Budget (OMB). Our ICR describes the information we seek to... requiring an applicant to submit documentary evidence of marriage are prescribed in 20 CFR 219.30. In the absence of documentary evidence, the RRB needs to determine if a valid marriage existed between a spouse...

78 FR 6150 - Agency Forms Submitted for OMB Review, Request for Comments

Science.gov (United States)

2013-01-29

... home addresses of all employees hired within the last year (new-hires). Form BA-6a, Form BA-6 Address... RAILROAD RETIREMENT BOARD Agency Forms Submitted for OMB Review, Request for Comments Summary: In... collection techniques or other forms of information technology. Comments to the RRB or OIRA must contain the...

10 CFR 1014.4 - Administrative claims; evidence and information to be submitted.

Science.gov (United States)

2010-01-01

... between injury and death. (8) Any other evidence or information that may have a bearing on either the.... (a) Death. In support of a claim based on death, the claimant may be required to submit the following evidence or information: (1) An authenticated death certificate or other competent evidence showing the...

75 FR 382 - Proposed Data Collections Submitted for Public Comment and Recommendations

Science.gov (United States)

2010-01-05

... Clearance Officer, 1600 Clifton Road NE., MS-D74, Atlanta, Georgia 30333; comments may also be sent by e... voluntarily submit these reports to CDC at variable frequencies, either weekly or monthly. CDC then calculates... cost to respondents other than their time. Estimate of Annualized Burden Hours Average Number of Number...

75 FR 48346 - Proposed Data Collections Submitted for Public Comment and Recommendations

Science.gov (United States)

2010-08-10

... plans and instrument, call 404-639-5960 and send comments to Maryam I. Daneshvar, CDC Reports Clearance... voluntarily submit these reports to CDC at variable frequencies, either weekly or monthly. CDC then calculates... reported annually is different for each. There is no cost to respondents other than their time. Estimated...

20 CFR 668.710 - What planning documents must an INA grantee submit?

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What planning documents must an INA grantee... Planning/Funding Process § 668.710 What planning documents must an INA grantee submit? Each grantee... participant services and expenditures covering the two-year planning cycle. We will, in consultation with the...

Pre and post operative facial angles in patients submitted to rhinoplasty

Directory of Open Access Journals (Sweden)

Soccol, Andréa T

2008-09-01

Full Text Available Introduction: Parameters used in facial aesthetic surgeries are currently based on POWELL and HUMPHREYS (1. These authors have formulated suitable relations between the face and the nose, and defined the face angles. Objective: To compare pre and pos-operative nasolabial, nasofrontal, nasomental and nasofacial angles in patients submitted to rhinoseptoplasty. Method: Prospective analysis of 37 patients submitted to rhinoplasty, with an average of 30±11 years of age, being 13 (36% men and 24 (64% women. The nasolabial, nasofrontal, nasomental and nasofacial angles were measured and compared, before and after the surgery, in profile pictures. Results: An average increase of 8.6o in the nasolabial angle was observed, of 8.5o in the nasofrontal and reduction of 2.3o in the nasofacial angle, and all the measures presented a statistically significant difference between the pre and pos-operative period. The nasomental angle increased, on average, 1.6o, a difference without statistical importance. Conclusions: The nasolabial and nasofrontal angles increase significantly after rhinoseptoplasty, while the nasofacial angle diminishes. There was no significant alteration in the nasomental angle with the accomplishment of the surgery.

Evaluation of continuing education of family health strategy teams for the early identification of suspected cases of cancer in children.

Science.gov (United States)

Costa, Ana Maria Aranha Magalhaes; Magluta, Cynthia; Gomes Junior, Saint Clair

2017-09-07

This study evaluated the influence of continuing education of family health strategy teams by the Ronald McDonald Institute program on the early diagnosis of cancer in children and adolescents. The study applied Habicht's model to evaluate the adequacy and plausibility of continuing education by using as outcome the number of children with suspected cancer who were referred to the hospital of references in the 1 year before and 1 year after intervention and the number of patients referred by intervention group and control group family health strategy teams. Medical records from each hospital of reference were used to collect information of suspect cases of cancer. Descriptive analyses were performed using frequencies and mean values. Chi-square tests were used to assess statistically significant differences between the groups and periods by using p-values family health strategy teams that underwent the intervention referred 3.6 times more number of children to hospital of references than did the control group. Only the intervention group showed an increase in the number of confirmed cases. This evaluation of a continuing education program for early identification of pediatric cancer showed that the program was adequate in achieving the established goals and that the results could be attributed to the program.

[Evaluation of quality of life in school children with a history of early severe malnutrition].

Science.gov (United States)

De Grandis, E S; Armelini, P A; Cuestas, E

2014-12-01

Severe malnutrition in young children may lead to long-term complications, in particular learning and psychosocial disorders linked to health related quality of life (HRQOL). The aim of this study was to evaluate HRQOL in children whit a history of severe malnutrition before 2 years of life, expecting to find lower scores in these patients. A comparative study was performed on schoolchildren between 5 and 12 years with a history of early severe malnutrition, excluding those with chronic diseases. The Controls were healthy siblings of patients. The sample size was estimated as 26 subjects per group (Total=52). Sociodemographic variables were recorded and the HRQOL was assessed with PedsQL4.0. Chi square and Student t test were applied. Significance level: Psocial dimension: 88.80±3.05 vs 95.71±1.52 (P<.0001), and school dimension: 74.58±3.80 vs 85.00±3.51 (P<.0001). Patients with a history of early severe malnutrition, showed significantly lower HRQOL scores compared with controls. Copyright © 2013 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

Evaluation of the Ramazzini Foundation Study of Methanol in Rats

Science.gov (United States)

Evaluation of the Ramazzini Foundation Study of Methanol in Rats: A Comparison of Diagnoses by the RF Study Pathologist and a Recent NTP Review Team, summarized by George Cruzan and submitted to the Methanol Institute

Late follow-up of patients submitted to subtotal splenectomy: late clinical, laboratory, imaging and functional with preservation of the upper splenic pole

Directory of Open Access Journals (Sweden)

Andy Petroianu

2008-09-01

Full Text Available objective: To evaluate the follow-up of patients submitted to splenectomy with preservation of the upper splenic pole. Methods: All patients undergoing subtotal splenectomy were invited to be reviewed. A total of 86 patients submitted to this surgery were studied. The procedure was performed due to one of the following conditions: portal hypertension due to schistosomiasis (n = 43, trauma (n = 31, Gaucher’s disease (n = 4, myeloid hepatosplenomegaly due to myelofibrosis (n = 3, splenomegalic retarded growth and sexual development (n = 2, severe pain due to splenic ischemia (n = 2 and pancreatic cystadenoma (n = 1. All patients underwent hematologic tests, immunological assessment, abdominal ultrasonography, computed tomography (CT, scintigraphy and endoscopy. Rresults: Increased white blood cell and platelet counts were the only hematological abnormalities. No immune deficit was found. Esophageal varices were still present in patients who underwent surgery because of portal hypertension, but none had a re-bleeding event. The ultrasonography, tomography and scintigraphy confirmed the presence of functional splenic remnants without significant size alteration. Conclusions: Subtotal splenectomy seems to be a safe procedure that can be useful to treat conditions involving the spleen. The functions of the splenic remnants are preserved during long periods of time.

γ-Herpesvirus load as surrogate marker of early death in HIV-1 lymphoma patients submitted to high dose chemotherapy and autologous peripheral blood stem cell transplantation.

Directory of Open Access Journals (Sweden)

Chiara Pratesi

Full Text Available Autologous stem cell transplantation (ASCT is a feasible procedure for human immunodeficiency virus-1 (HIV-1 lymphoma patients, whose underlying disease and intrinsic HIV-1- and ASCT-associated immunodeficiency might increase the risk for γ-herpesvirus load persistence and/or reactivation. We evaluated this hypothesis by investigating the levels of Epstein-Barr virus (EBV- and Kaposi sarcoma-associated herpesvirus (KSHV-DNA levels in the peripheral blood of 22 HIV-1-associated lymphoma patients during ASCT, highlighting their relationship with γ-herpesvirus lymphoma status, immunological parameters, and clinical events. EBV-DNA was detected in the pre-treatment plasma and peripheral blood mononuclear cells (PBMCs of 12 (median 12,135 copies/mL and 18 patients (median 417 copies/10(6 PBMCs, respectively; the values in the two compartments were correlated (r = 0.77, p = 0.0001. Only EBV-positive lymphomas showed detectable levels of plasma EBV-DNA. After debulking chemotherapy, plasma EBV-DNA was associated with lymphoma chemosensitivity (p = 0.03 and a significant higher mortality risk by multivariate Cox analysis adjusted for EBV-lymphoma status (HR, 10.46, 95% CI, 1.11-98.32, p = 0.04. After infusion, EBV-DNA was detectable in five EBV-positive lymphoma patients who died within six months. KSHV-DNA load was positive in only one patient, who died from primary effusion lymphoma. Fluctuations in levels of KSHV-DNA reflected the patient's therapy and evolution of his underlying lymphoma. Other γ-herpesvirus-associated malignancies, such as multicentric Castleman disease and Kaposi sarcoma, or end-organ complications after salvage treatment were not found. Overall, these findings suggest a prognostic and predictive value of EBV-DNA and KSHV-DNA, the monitoring of which could be a simple, complementary tool for the management of γ-herpesvirus-positive lymphomas in HIV-1 patients submitted to ASCT.

Test Review for Preschool-Wide Evaluation Tool (PreSET) Manual: Assessing Universal Program-Wide Positive Behavior Support in Early Childhood

Science.gov (United States)

Rodriguez, Billie Jo

2013-01-01

The Preschool-Wide Evaluation Tool (PreSET; Steed & Pomerleau, 2012) is published by Paul H. Brookes Publishing Company in Baltimore, MD. The PreSET purports to measure universal and program-wide features of early childhood programs' implementation fidelity of program-wide positive behavior intervention and support (PW-PBIS) and is,…

Evaluation of production and gamma radiation effects in pasta enriched with brown flaxseed bagasse (Linum usitatissimum L.)

International Nuclear Information System (INIS)

Oliveira, Marcia Lage de; Arthur, Valter; Oliveira, Ana Claudia Sampaio; Polesi, Luiz Fernando; Silva, Lucia Cristina Aparecida Santos; Jesus, Jose Paulo de

2013-01-01

Flat pasta was produced using eggs, wheat flour added with brown flaxseed bagasse in 0,20% and 40% proportions. The pasta obtained in 20% and 40% proportions were irradiated with 20kGy and submitted to evaluation through determinations of moisture, acidity, ph., chemical composition and baking test. Utilizing the same proportions it was also produced pasta with the flaxseed bagasse flour irradiated with 10kGy and submitted to the same evaluations. Found values for different kinds of pasta, for moisture, acidity and ph. can be considered normal within the range of acceptation. (author)

Evaluation of production and gamma radiation effects in pasta enriched with brown flaxseed bagasse (Linum usitatissimum L.)

Energy Technology Data Exchange (ETDEWEB)

Oliveira, Marcia Lage de; Arthur, Valter; Oliveira, Ana Claudia Sampaio, E-mail: mlageoli@hotmail.com, E-mail: arthur@cena.usp.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Polesi, Luiz Fernando; Silva, Lucia Cristina Aparecida Santos [Centro de Energia Nuclear na Agricultura (CENA/USP), Piracicaba, SP (Brazil); Jesus, Jose Paulo de [Universidade de Sao Paulo (ESALQ/USP), Piracicaba, SP (Brazil). Escola Superior de Agricultura Luiz de Queiroz; Oliveira, Andrea Lage de [Universidade Federal de Sao Carlos (UFSCAR), Araras, SP (Brazil)

2013-07-01

Flat pasta was produced using eggs, wheat flour added with brown flaxseed bagasse in 0,20% and 40% proportions. The pasta obtained in 20% and 40% proportions were irradiated with 20kGy and submitted to evaluation through determinations of moisture, acidity, ph., chemical composition and baking test. Utilizing the same proportions it was also produced pasta with the flaxseed bagasse flour irradiated with 10kGy and submitted to the same evaluations. Found values for different kinds of pasta, for moisture, acidity and ph. can be considered normal within the range of acceptation. (author)

Evaluation and Assessment in Early Social Science

Science.gov (United States)

Hus, Vlasta; Matjašic, Jasmina

2017-01-01

Authenticity is an important element in the newer models of teaching, evaluation and assessment. Due to the fact that it is quite unclear how authentic evaluation and assessment should be implemented into practice, teachers still cling too much to traditional forms of knowledge evaluation and assessment. First, some basic theoretical facts on…

Evaluation of early endoscopic realignment of post-traumatic complete posterior urethral rupture

Directory of Open Access Journals (Sweden)

Yaser M Abdelsalam

2013-01-01

Full Text Available Introduction: to report our experience with 41 patients treated by early endoscopic realignment of complete post-traumatic rupture urethra. Materials and Methods: The study includes patients presented to our institute, between May 2004 and April 2009, with post-traumatic complete posterior urethral disruption. Preoperative retrograde urethrography, voiding cystourethrography and abdominopelvic CT were performed to evaluate the urethral defect length, the bladder neck competence, the prostate position, and the extent of the pelvic hematoma. Within the first week after trauma, antegrade and retrograde urethroscopy were performed to identify both urethral ends and insert urethral catheter. Patients were followed up by pericatheter retrograde urethrogram monthly postoperatively till catheter removal on disappearance of extravasation. Retrograde urethrography, voiding cystourethrography and urethroscopy were performed 1 month after the removal of the catheter. Follow-up abdominal ultrasound and uroflowmetry monthly till 6 months, bimonthly till 1 year, and every 3 months thereafter were encouraged. Urinary continence and postoperative erectile dysfunction were assessed by direct patient interview. Results: Forty one patients in the age group 17-61 years (mean 37.9 were treated. Patients were followed up for 12-36 months (mean 17 months. Complete healing of the urethra occurred in 18 patients (43.9%. Passable urethral stricture developed in 15 patients (36.6%. Complete urethral obstruction occurred in eight patients (19.5%. Conclusions: Early endoscopic realignment for complete posterior urethral rupture is a feasible technique with no or minimal intraoperative complications. The technique is successful as the definitive line of therapy in reasonable number of patients and seems to render further future interventions for inevitable urethral stricture easier.

Report of the evaluation by the ad hoc review committee on advanced photon and synchrotron radiation research. In-advance evaluation in fiscal year 2001

International Nuclear Information System (INIS)

2001-11-01

The Research Evaluation Committee, which consisted of 13 members from outside of the Japan Atomic Energy Research Institute (JAERI), set up an Ad Hoc Review Committee on Advanced Photon and Synchrotron Radiation Research in accordance with the 'Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations in order to evaluate the adequacy of the R and D programs to be implemented for five years starting in Fiscal Year 2002 at Advanced Photon Research Center and at Synchrotron Radiation Research Center in Kansai Research Establishment of JAERI. The Ad Hoc Review Committee consisted of ten specialists from outside of JAERI. The Ad Hoc Review Committee conducted its activities from May to July 2001. The evaluation was performed on the basis of the materials submitted in advanced and of the oral presentations made at the Ad Hoc Review Committee meeting which was held on June 21, 2001, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Ad Hoc Review Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on July 12, 2001. This report describes the result of the evaluation by the Ad Hoc Review Committee on Advanced Photon and Synchrotron Radiation Research. (author)

77 FR 5850 - Notice of Random Assignment Study To Evaluate Workforce Investment Act Adult and Dislocated...

Science.gov (United States)

2012-02-06

... evaluation, the evaluation team, led by researchers from Mathematica and its subcontractor MDRC, submitted... anyone to services to which they would not have referred them in the absence of the study. The study...

Use of X - Rays for the evaluation of internal damages provoked by corn seed drying and the effect of those damages upon the seeds quality

International Nuclear Information System (INIS)

Obando Flor, Ebert Pepe; Moreira de Carvalho, Maria Laene

2002-01-01

The work was conducted in the seed analysis laboratory of the department of agriculture and forest sciences of the Universidade Federal de Lavras (Federal University of Lavras. MG), over the period 1999 - 2000. Aiming to evaluate the efficiency of utilization of X - rays in the identification of the several types of internal damages provoked by corn seed drying to high temperatures as well as the effect of those damages upon the physiological quality of stored seeds, lots of the cultivars AG1143 and BR 106 were submitted to drying at the temperature of 50 degrades Celsius. The lots were divided into two categories according to the presence or not of internal damages visible with the naked eye submitted to the X - ray test (for 45 at 25 Kvp of radiation intensity) afterwards. They were separated into three sub lots. CDVCDRX (with visual damages and detected by X - ray) SDVSDRX (without visual damages and with damages detected by X ray). The sub lots were evaluated in their physiological quality by viability and vigor tests. The results showed the efficiency of X ray in detecting internal damages of drying not observed by visual analysis. The vigor of corn seeds with internal drying damages is affected in several manners, depending on the cultivars, evaluation time and sort of damage internal damages of drying detected by the radiographical analysis in spite of not affecting early viability, when they occurs in the two directions horizontal and vertical (Double damage) decrease the vigor of seeds after storage

Epidural phlebography - Its diagnostic value in the evaluation of lumbar discal hernia when compared with radiculography

International Nuclear Information System (INIS)

Santos, M.B. dos

1987-01-01

The objective of this study was to compare two neuroradiological methods used in the diagnosis of lumbar discal hernia-radiculography and epidural phlebography - as the result of the evaluation of 36 patients submitted to both procedures at the X-ray Diagnostic Service of the University Hospital of the University of Rio de Janeiro. The results of both examinations to which all the patients were submitted, were compared with the surgical reports (laminectomy) to which some of the patients were submitted. In this way it was possible to determine the sensitivity and the specificity of both methods. From these comparative study it could be verified that the procedures evaluated have a similar potentiality for the diagnosis of discal hernia. The analysis of other aspects of the two procedures showed that phlebography is more expensive, more difficult to interpret and to perform than radiculography. In terms of complications or side effects that may occur during or after the exams these can be more severe and may happen more oftern in the case of radiculography. In conclusion, we recommend radiculography as the method of choice for initial evaluation of a patient suspect of discal hernia. Phlebography should only be initially used for the evaluation of patients who refuse to submit themselves to lumbar puncture for the radiculography. In those patients where discal hernia is strongly suspected and the radiculography proves to be normal, the epidural radiculography could be used, without greater chances, however, of supplying more information that could benefit the patien in clarifying this clinical condition. (Author) [pt

Gross and histological evaluation of early lesions of navicular bone and deep digital flexor tendon in horses

Directory of Open Access Journals (Sweden)

Komosa Marcin

2014-03-01

Full Text Available The study aimed at evaluation of pathological lesions on flexor surface of navicular bone and deep digital flexor tendon in horses graded in standard X-ray examination as 2 (fair. The evaluation was performed on fifteen horses (6-9 years of age. Analysis procedure involved examining navicular bones on X-ray pictures, post-slaughter preparation of navicular bones from the hoof capsule, macroscopic evaluation of fibrocartilage on flexor surface, and analysis of histologic preparations. In horses with navicular bones graded as 2, early pathological changes have already developed, even if such horses were not lame. The pathological changes included fibrillation and disruption of deep digital flexor tendon surface, loss of fibrocartillage in sagittal ridge area of navicular bone, thinning of subchondral bone on its flexor surface, and fibromyxoid changes in chondroid matrix. In terms of clinical relevance, more studies are needed to understand the sequence of changes in a better way.

Review of early assessment models of innovative medical technologies.

Science.gov (United States)

Fasterholdt, Iben; Krahn, Murray; Kidholm, Kristian; Yderstræde, Knud Bonnet; Pedersen, Kjeld Møller

2017-08-01

Hospitals increasingly make decisions regarding the early development of and investment in technologies, but a formal evaluation model for assisting hospitals early on in assessing the potential of innovative medical technologies is lacking. This article provides an overview of models for early assessment in different health organisations and discusses which models hold most promise for hospital decision makers. A scoping review of published studies between 1996 and 2015 was performed using nine databases. The following information was collected: decision context, decision problem, and a description of the early assessment model. 2362 articles were identified and 12 studies fulfilled the inclusion criteria. An additional 12 studies were identified and included in the review by searching reference lists. The majority of the 24 early assessment studies were variants of traditional cost-effectiveness analysis. Around one fourth of the studies presented an evaluation model with a broader focus than cost-effectiveness. Uncertainty was mostly handled by simple sensitivity or scenario analysis. This review shows that evaluation models using known methods assessing cost-effectiveness are most prevalent in early assessment, but seems ill-suited for early assessment in hospitals. Four models provided some usable elements for the development of a hospital-based model. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.

There is an association between disease location and gestational age at birth in newborns submitted to surgery due to necrotizing enterocolitis.

Science.gov (United States)

Feldens, Letícia; Souza, João C K de; Fraga, José C

2017-08-30

To evaluate if there are differences regarding disease location and mortality of necrotizing enterocolitis, according to the gestational age at birth, in newborns submitted to surgery due to enterocolite. A historical cohort study of 198 newborns submitted to surgery due to necrotizing enterecolitis in a tertiary hospital, from November 1991 to December 2012. The newborns were divided into different categories according to gestational age (<30 weeks, 30-33 weeks and 6 days, 34-36 weeks and 6 days, and ≥37 weeks), and were followed for 60 days after surgery. The inclusion criterion was the presence of histological findings of necrotizing enterocolitis in the pathology. Patients with single intestinal perforation were excluded. The jejunum was the most commonly affected site in extremely premature infants (p=0.01), whereas the ileum was the most commonly affected site in premature infants (p=0.002), and the colon in infants born at term (p<0.001). With the increasing gestational age, it was observed that intestinal involvement decreased for the ileum and the jejunum (decreasing from 45% to 0% and from 5% to 0%, respectively), with a progressive increase in colon involvement (0% to 84%). Total mortality rate was 45.5%, and no statistical difference was observed in the mortality at different gestational ages (p=0.287). In newborns submitted to surgery due to necrotizing enterocolitis, the disease in extremely preterm infants was more common in the jejunum, whereas in preterm infants, the most affected site was the ileum, and in newborns born close to term, it was the colon. No difference in mortality was observed according to the gestational age at birth. Copyright © 2017 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

The value of superpower-submitted INDCs in cooperative and non-cooperative action scenarios: economic impact, dynamic risk, and temperature rise

Science.gov (United States)

Augustin, C. M.

2015-12-01

As the 2015 Paris climate talks near, policy discussions are focused on "intended nationally determined contributions" (INDCs) submitted in advance of the discussions. As the major global emitters - specifically the United States and China - have already submitted their INDCs, we have a point of comparison for evaluating the relative potential impacts of the proposed targets. By applying integrated assessment models to robust, publicly available data sets,we aim to evaluate the interplay between climate change and economic development, comment on emissions reduction scenarios in cooperative and non-cooperative situations, and assess the dynamic risks of multiple regional emissions scenarios. We use both the RICE model and the C-ROADS model to examine alternative regional outcomes for emissions, climate change, and damages,under different reduction scenarios, including a scenario where geo-engineering plays a prominent role. These simulators allow us to vary emissions, population, and economic levels in China and the United States specifically to comment on the international climate risk impact of actors working jointly - or not - toward a global climate goal. In a complementary piece of analysis we seek to understand the value judgments, trade-offs, and regional policies that would lead to favorable climate finance flows. To reach an international sample of industry decision-makers, we propose a novel application of a standard discrete-choice survey methodology. A conjoint analysis requires a participant to chose between combinations of attributes and identify trade-offs while allowing the researcher to determine the relative importance of each individual attribute by mathematically assessing the impact each attribute could have on total item utility. As climate policy negotiations will consist of allocation of scarce resources and rejection of certain attributes, a conjoint analysis is an ideal tool for evaluating policy outcomes. This research program seeks to

75 FR 72847 - Agency Forms Submitted for OMB Review, Request for Comments

Science.gov (United States)

2010-11-26

... Form RRB W-4P annually. The completion time for Form RRB W-4P varies depending on individual circumstances. The estimated average(s) for Form RRB W-4P is 39 minutes for recordkeeping, 24 minutes for...: 3220-0149. Form(s) submitted: RRB-W-4P, Withholding Certificate for Railroad Retirement Monthly Annuity...

Early Functional Abilities

DEFF Research Database (Denmark)

Lorentzen, Jakob; Poulsen, Ingrid

2005-01-01

Early Functional Abilities (EFA), - en skala til evaluering af behandlingsforløb af svært hjerneskadede patienter i forbindelse med tidlig rehabilitering. Formål At monitorere og dokumentere rehabiliteringsforløbet for svært hjerneskadede patienter, hvor funktionsniveauet endnu ikke kan registreres...

14 CFR 330.31 - What data must air carriers submit concerning ASMs or RTMs?

Science.gov (United States)

2010-01-01

... combination passenger/cargo carrier, you must have submitted your August 2001 total completed ASM report to... correct an error that you document to the Department, you must not alter the ASM or RTM reports you...

Longitudinal follow-up to evaluate speech disorders in early-treated patients with infantile-onset Pompe disease.

Science.gov (United States)

Zeng, Yin-Ting; Hwu, Wuh-Liang; Torng, Pao-Chuan; Lee, Ni-Chung; Shieh, Jeng-Yi; Lu, Lu; Chien, Yin-Hsiu

2017-05-01

Patients with infantile-onset Pompe disease (IOPD) can be treated by recombinant human acid alpha glucosidase (rhGAA) replacement beginning at birth with excellent survival rates, but they still commonly present with speech disorders. This study investigated the progress of speech disorders in these early-treated patients and ascertained the relationship with treatments. Speech disorders, including hypernasal resonance, articulation disorders, and speech intelligibility, were scored by speech-language pathologists using auditory perception in seven early-treated patients over a period of 6 years. Statistical analysis of the first and last evaluations of the patients was performed with the Wilcoxon signed-rank test. A total of 29 speech samples were analyzed. All the patients suffered from hypernasality, articulation disorder, and impairment in speech intelligibility at the age of 3 years. The conditions were stable, and 2 patients developed normal or near normal speech during follow-up. Speech therapy and a high dose of rhGAA appeared to improve articulation in 6 of the 7 patients (86%, p = 0.028) by decreasing the omission of consonants, which consequently increased speech intelligibility (p = 0.041). Severity of hypernasality greatly reduced only in 2 patients (29%, p = 0.131). Speech disorders were common even in early and successfully treated patients with IOPD; however, aggressive speech therapy and high-dose rhGAA could improve their speech disorders. Copyright © 2016 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

78 FR 19725 - Merchant Mariner Medical Evaluation Program

Science.gov (United States)

2013-04-02

... DEPARTMENT OF HOMELAND SECURITY Coast Guard [Docket No. USCG-2013-0089] Merchant Mariner Medical... the comment, if submitted on behalf of an association, business, labor union, etc.). You may review a... evaluation, noting advantages and disadvantages of the different systems. We would also be interested in...

Continuity, Support, Togetherness and Trust: Findings from an Evaluation of a University-Administered Early Professional Development Programme for Teachers in England

Science.gov (United States)

McIntyre, Joanna; Hobson, Andrew J.; Mitchell, Nick

2009-01-01

This article discusses the evaluation of a unique university-based early professional development (EPD) programme in England that enabled newly and recently qualified teachers to have continued contact with their initial teacher preparation provider. The programme was designed to enhance the induction, EPD and retention of beginning teachers of…

Assessment of facial profile changes in Class I biprotrusion adolescent subjects submitted to orthodontic treatment with extractions of four premolars

Directory of Open Access Journals (Sweden)

Claudia Trindade Mattos

2012-06-01

Full Text Available OBJECTIVE: To evaluate cephalometric changes in tooth and profile position in young adolescent individuals with Class I biprotrusion submitted to orthodontic treatment with extractions of four first premolars. METHODS: Pre and posttreatment lateral cephalometric radiographs from 20 patients with Class I biprotrusion malocclusion were used to evaluate the following measurements: nasolabial angle, distance from lips to E line, distance from lips, incisors, tip of the nose and soft tissue pogonion to Sy line. RESULTS: All measurements showed significant changes after treatment (p<0.05, except the distance from lips and soft tissue pogonion to Sy line. There was a positive correlation between the retraction of incisors and the change of upper and lower lips (0.803/0.925; p<0.001. CONCLUSION: The profile retrusion observed occurred more due to nose growth than to lips retraction. The response from soft tissues to incisors retraction showed a great variability.

76 FR 2418 - Proposed Information Collection Request Submitted for Public Comment and Recommendations...

Science.gov (United States)

2011-01-13

... needed by OSHA to carry out enforcement and intervention activities to provide workers a safe and healthy... current data available, and to comment on their accuracy or appropriateness in today's workplace situation... about submitting personal information such as social security numbers and date of birth. Although all...

Characteristics of low back pain in adolescent patients with early-stage spondylolysis evaluated using a detailed visual analogue scale.

Science.gov (United States)

Sugiura, Shiro; Aoki, Yasuchika; Toyooka, Takeshi; Shiga, Tetsuo; Otsuki, Kazumi; Aikawa, Emi; Oyama, Takato; Kitoh, Kazuhisa; Chikako, Sakaida; Takata, Yuka; Ishizaki, Tohru; Omori, Yasutaka; Kiguchi, Yasumi; Takata, Akito; Kote, Ayako; Nakanishi, Yasuko; Matsushita, Yukio; Suzuki, Takane; Mori, Chisato; Takahashi, Kazuhisa; Nishikawa, Satoru

2015-01-01

Retrospective comparative cohort study. To elucidate the characteristics of low back pain (LBP) in adolescent patients with early-stage spondylolysis (ESS). ESS is a common cause of acute LBP in adolescents. When treating patients with ESS, early diagnosis is important; however, early diagnosis is difficult without magnetic resonance imaging. Adolescent patients (n = 77) with acute LBP showing no pathological findings on plain radiography were included (<1 m after onset). Patients were divided into ESS and nonspecific LBP (NS-LBP) groups by conducting magnetic resonance imaging; patients showing no pathological findings that explain the cause of LBP were classified as NS-LBP. LBP was evaluated using a traditional visual analogue scale (VAS; 0-10 cm), Oswestry Disability Index, and a detailed VAS scoring system in which pain is independently evaluated in 3 different postural situations (in motion, standing, and sitting); the values were compared between the 2 groups. Of 77 patients, 41 (mean age: 14.6 yr; 33 adolescent boys/8 adolescent girls) had ESS and 36 (mean age: 14.3 yr; 20 adolescent boys/16 adolescent girls) were considered to have NS-LBP. Respective traditional VAS and Oswestry Disability Index scores were 4.9, 16.1 in the ESS group, and 6.2, 26.3 in the NS-LBP group. Both scores were significantly higher in the NS-LBP group. The results of the detailed VAS revealed that the ESS group showed significantly greater pain intensity while in motion than while standing or sitting (4.2, 2.0, and 2.0, respectively), whereas the NS-LBP group showed similar pain intensities in all 3 postural situations (5.3, 4.0, and 4.9, respectively). This study revealed that LBP characteristics may provide important information for distinguishing ESS from other low back disorders. Because early diagnosis is essential for the treatment of ESS, MRI examination is recommended for patients showing severe pain in motion, but less pain when standing or sitting.