WorldWideScience

Sample records for submit submit advanced

  1. 15 CFR 711.7 - Where to submit declarations, reports and advance notifications.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Where to submit declarations, reports and advance notifications. 711.7 Section 711.7 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL...

  2. 15 CFR 711.2 - Who submits declarations, reports, and advance notifications.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Who submits declarations, reports, and advance notifications. 711.2 Section 711.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS...

  3. 41 CFR 301-52.14 - What must I do with any travel advance outstanding at the time I submit my travel claim?

    Science.gov (United States)

    2010-07-01

    ... travel advance outstanding at the time I submit my travel claim? 301-52.14 Section 301-52.14 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES... § 301-52.14 What must I do with any travel advance outstanding at the time I submit my travel claim? You...

  4. 41 CFR 102-118.200 - Can a TSP demand advance payment for the transportation charges submitted on a bill of lading...

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Can a TSP demand advance... (gbl) Or Government Transportation Request (gtr) (until Form Retirement) § 102-118.200 Can a TSP demand advance payment for the transportation charges submitted on a bill of lading (including GBL)? No, a TSP...

  5. 7 CFR 701.13 - Submitting requests.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Submitting requests. 701.13 Section 701.13 Agriculture... ADMINISTERED UNDER THIS PART § 701.13 Submitting requests. (a) Subject to the availability of funds, the Deputy Administrator shall provide for an enrollment period for submitting ECP cost-share requests. (b) Requests may be...

  6. How to Submit a Proposal to ONR

    Science.gov (United States)

    2012-08-01

    Click to edit Master title style How   to  Submit  a  Proposal  to  ONR   Navy  Gold  Coast  Small  Business  Procurement...control number. 1. REPORT DATE AUG 2012 2. REPORT TYPE 3. DATES COVERED 00-00-2012 to 00-00-2012 4. TITLE AND SUBTITLE How to Submit a Proposal to

  7. 20 CFR 405.333 - Submitting documents.

    Science.gov (United States)

    2010-04-01

    ... Employees' Benefits SOCIAL SECURITY ADMINISTRATION ADMINISTRATIVE REVIEW PROCESS FOR ADJUDICATING INITIAL DISABILITY CLAIMS Administrative Law Judge Hearing § 405.333 Submitting documents. All documents prepared and... fullest extent practicable and delivered or mailed to the administrative law judge within the time frames...

  8. 31 CFR 103.81 - Submitting requests.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Submitting requests. 103.81 Section 103.81 Money and Finance: Treasury Regulations Relating to Money and Finance FINANCIAL RECORDKEEPING... which the request is made. (b) A request filed by a corporation shall be signed by a corporate officer...

  9. A Checklist for Submitting Your Risk Management Plan (RMP)

    Science.gov (United States)

    Important information about 2014 submissions and a checklist to consider in preparing and resubmitting a 5-year update, as required by 40 CFR part 68. Use the RMP*eSubmit software application, which replaced RMP*Submit.

  10. CATTLE PRODUCTIVE PERFORMANCE EVALUATION CONFINED SUBMITTED IMMUNOCASTRATION

    Directory of Open Access Journals (Sweden)

    J. M. Maluf

    2016-09-01

    Full Text Available In order to evaluate the performance and carcass characteristics of cattle cross breeds ½ Aberdeen Angus x ½Nelore and Nelore confined submitted to immunocastration 218 male animals were used, feedlot, averaging 342 kg, divided into three experimental groups, T1: 117 steers ½ Angus x ½ Nelore no castrated (ANC, T2: 51 Nelore steers uncastrated (NNC and T3: 50 Nellore steers immunocastrated (NIC. The experiment lasted 144 days of confinement. The selection of animals for group formation was according to the individual weight, breed, sex condition and age. For immunocastration it wasused Bopriva® vaccine. The rating was finished according to the parameter used by the meatpacking industry ranging from 1 to 5. The experimental design was completely randomized in three groups. For the analyzes the variables studied statistics were submitted to analysis of variance (ANOVA and Tukey test both at the 5% level of significance. The results showed differences (p <0.01 at various features of productive performance and carcass between treatments. For slaughter weight, the ANC animals were higher (with 582.1 kg to Nelore, regardless of sexual condition, and the NNC were in turn heavier than the NIC, 527.4 and 503.7 respectively. Finally, it observed that the use of immunocastration in Nellore animals provided a decrease in productive performance of confined animals, but provided better finish carcass similar to crossbred (ANC.

  11. [Buccal manifestations in patients submitted to chemotherapy].

    Science.gov (United States)

    Hespanhol, Fernando Luiz; Tinoco, Eduardo Muniz Barretto; Teixeira, Henrique Guilherme de Castro; Falabella, Márcio Eduardo Vieira; Assis, Neuza Maria de Souza Picorelli

    2010-06-01

    Several changes in the oral cavity due to chemotherapy can be observed and can lead to important systemic complications, increasing the time of the patient in hospital and the costs of the treatment as well as affect the quality of life of the patients. The aim of this study was to assess the oral manifestation in patients treated with chemotherapy according to sex, age and tumor type. Data was collected in an oncology hospital in Juiz de Fora, Minas Gerais State, from patients' records that were submitted to oncologic treatment. It was possible to verify that mucositis, associated or not to other type of lesions, was the most common lesion in both sex of all ages (15.5%). Xerostomia and other lesions, such as Candida infection and aphthous lesions, were also present. It is possible to improve the quality of life of the patient during and after anti-neoplastic therapies through a protocol of odontological assistance that includes changes of the oral environment previous to chemotherapy such as profilaxis, caries removal, treatment of periodontal and periapical lesions, oral hygiene instructions, diet orientation and laser therapy. It is very important the insertion of the dentist in the oncologic medical team for the early diagnosis of the oral manifestation and follow-up during treatment time.

  12. 75 FR 41579 - Submitting Airline Data via the Internet

    Science.gov (United States)

    2010-07-16

    ... Transportation 14 CFR Parts 217, 234, 241, et al. Submitting Airline Data via the Internet; Final Rule #0;#0... Submitting Airline Data via the Internet AGENCY: Office of the Secretary, DOT. ACTION: Final rule. SUMMARY..., traffic, operational and consumer data reports electronically via the Internet using the comma separated...

  13. Learning Disability Documentation in Higher Education: What Are Students Submitting?

    Science.gov (United States)

    Sparks, Richard L.; Lovett, Benjamin J.

    2014-01-01

    This study examined the supporting documentation submitted by students with learning disability (LD) diagnoses. The participants were 210 students who were enrolled in a college support program for students with disabilities at a private liberal arts college. Findings showed that although most students submitted a psychoeducational evaluation,…

  14. 7 CFR 28.954 - Costs of submitting samples.

    Science.gov (United States)

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER... Tests § 28.954 Costs of submitting samples. The transportation of samples to a laboratory for testing...

  15. Perioperative fasting time among cancer patients submitted to gastrointestinal surgeries

    OpenAIRE

    Nayara de Castro Pereira; Ruth Natalia Teresa Turrini; Vanessa de Brito Poveda

    2017-01-01

    Abstract OBJECTIVE To identify the length of perioperative fasting among patients submitted to gastrointestinal cancer surgeries. METHOD Retrospective cohort study, developed by consulting the medical records of 128 patients submitted to gastrointestinal cancer surgeries. RESULTS The mean of total length of fasting was 107.6 hours. The total length of fasting was significantly associated with the number of symptoms presented before (p=0.000) and after the surgery (p=0.007), the length of h...

  16. Science Based Governance? EU Food Regulation Submitted to Risk Analysis

    NARCIS (Netherlands)

    Szajkowska, A.; Meulen, van der B.M.J.

    2014-01-01

    Anna Szajkowska and Bernd van der Meulen analyse in their contribution, Science Based Governance? EU Food Regulation Submitted to Risk Analysis, the scope of application of risk analysis and the precautionary principle in EU food safety regulation. To what extent does this technocratic,

  17. 15 CFR 711.5 - Numerical precision of submitted data.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Numerical precision of submitted data. 711.5 Section 711.5 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS...

  18. Teaching undergraduates how to write and submit a research manuscript.

    Science.gov (United States)

    Smith, Linda S

    2004-01-01

    Undergraduate nursing students have long been excluded from performing original theory-based nursing research due to severe time and work constraints. However, without actual research opportunities, students also lack research-writing experiences. This author describes successful strategies for teaching an undergraduate class how to write and submit a manuscript that describes an original research project.

  19. 42 CFR 83.8 - How is a petition submitted?

    Science.gov (United States)

    2010-10-01

    ... HEALTH RESEARCH AND RELATED ACTIVITIES PROCEDURES FOR DESIGNATING CLASSES OF EMPLOYEES AS MEMBERS OF THE... Procedures for Adding Classes of Employees to the Cohort § 83.8 How is a petition submitted? The petitioner(s... NIOSH through direct request (1-800-35-NIOSH) or on the Internet at www.cdc.gov/niosh/ocas. ...

  20. 40 CFR 63.4120 - What reports must I submit?

    Science.gov (United States)

    2010-07-01

    ... organic HAP in waste materials according to § 63.4151(e)(4). You do not need to submit background data... § 63.4151 and, if applicable, the calculation used to determine the mass of organic HAP in waste... CPMS was inoperative, except for zero (low-level) and high-level checks. (7) The date, time, and...

  1. 40 CFR 63.4520 - What reports must I submit?

    Science.gov (United States)

    2010-07-01

    ... waste materials according to § 63.4551(e)(4). You do not need to submit background data supporting these... of § 63.4551; and, if applicable, the calculation used to determine mass of organic HAP in waste... each CPMS was inoperative, except for zero (low-level) and high-level checks. (vii) The date, time, and...

  2. 40 CFR 63.3920 - What reports must I submit?

    Science.gov (United States)

    2010-07-01

    ... waste materials according to § 63.3951(e)(4). You do not need to submit background data supporting these... of § 63.3951; and, if applicable, the calculation used to determine mass of organic HAP in waste... each CPMS was inoperative, except for zero (low-level) and high-level checks. (vii) The date, time, and...

  3. 40 CFR 63.4720 - What reports must I submit?

    Science.gov (United States)

    2010-07-01

    ... HAP in waste materials according to § 63.4751(e)(4). You do not need to submit background data... applicable, the calculation used to determine mass of organic HAP in waste materials according to § 63.4751(e... inoperative, except for zero (low-level) and high-level checks. (vii) The date, time, and duration that each...

  4. 77 FR 66467 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2012-11-05

    ... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public... technology. Written comments should be received within 60 days of this notice. Proposed Project National... exchange, data content and format, data quality assurance, data use, collaborative relationships, advanced...

  5. First paper from Tevatron Run II submitted by CDF collaboration

    CERN Multimedia

    2003-01-01

    "Scientists of the Collider Detector at Fermilab submitted today (March 19) the first scientific publication of Collider Run II to the science journal Physical Review D. The paper titled "Measurement of the Mass Difference m(Ds+)-m(D+) at CDF II" summarizes the results of an analysis carried out by CDF scientists Christoph Paus and Ivan Furic, MIT, describing the mass measurement of particles containing charm quarks" (1 page).

  6. 75 FR 81204 - Notice of Public Information Collection Requirements Submitted to OMB for Review

    Science.gov (United States)

    2010-12-27

    ... and organizational information on NGOs working in international development and humanitarian relief...; ] AGENCY FOR INTERNATIONAL DEVELOPMENT Notice of Public Information Collection Requirements Submitted to OMB for Review SUMMARY: U.S. Agency for International Development (USAID) has submitted the following...

  7. 21 CFR 1.279 - When must prior notice be submitted to FDA?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false When must prior notice be submitted to FDA? 1.279... Imported Food § 1.279 When must prior notice be submitted to FDA? (a) Except as provided in paragraph (c) of this section, you must submit the prior notice to FDA and the prior notice submission must be...

  8. 42 CFR 405.946 - Evidence to be submitted with the redetermination request.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Evidence to be submitted with the redetermination...) Redeterminations § 405.946 Evidence to be submitted with the redetermination request. (a) Evidence submitted with... the contractor's determination and should include any evidence that the party believes should be...

  9. 40 CFR 60.2625 - When must I submit my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... or Before November 30, 1999 Model Rule-Waste Management Plan § 60.2625 When must I submit my waste management plan? You must submit a waste management plan no later than the date specified in table 1 of this...

  10. 40 CFR 62.14585 - When must I submit my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false When must I submit my waste management... Commenced Construction On or Before November 30, 1999 Waste Management Plan § 62.14585 When must I submit my waste management plan? You must submit a waste management plan no later than April 5, 2004. ...

  11. 40 CFR 62.14715 - When must I submit my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false When must I submit my waste management... submit my waste management plan? You must submit the waste management plan no later than April 5, 2004. ... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That...

  12. 40 CFR 60.3011 - When must I submit my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Model Rule-Waste Management Plan § 60.3011 When must I submit my waste management plan? You must submit a waste management plan no later than 60 days following the initial performance test as specified in...

  13. 40 CFR 60.2060 - When must I submit my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Management Plan § 60.2060 When must I submit my waste management plan? You must submit a waste management... Commercial and Industrial Solid Waste Incineration Units for Which Construction Is Commenced After November...

  14. 40 CFR 60.2900 - When must I submit my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Waste Management Plan § 60.2900 When must I submit my waste management plan? You must submit a waste management plan prior to commencing construction, reconstruction, or modification. ...

  15. 21 CFR 803.13 - Do I need to submit reports in English?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Do I need to submit reports in English? 803.13... in English? (a) Yes. You must submit all written or electronic equivalent reports required by this part in English. (b) If you submit any reports required by this part in an electronic medium, that...

  16. 40 CFR 152.93 - Citation of a previously submitted valid study.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Citation of a previously submitted... Data Submitters' Rights § 152.93 Citation of a previously submitted valid study. An applicant may... the citation is necessary. (b) Study previously submitted by another person. If the applicant is not...

  17. 7 CFR 28.46 - Method of submitting samples and types.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Method of submitting samples and types. 28.46 Section... Standards Act Sample Or Type Comparison § 28.46 Method of submitting samples and types. The method of submitting samples and types for comparison shall be the same as that prescribed in this subpart for...

  18. 45 CFR 149.320 - Universe of claims that must be submitted.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Universe of claims that must be submitted. 149.320 Section 149.320 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH... Universe of claims that must be submitted. (a) Claims submitted for an early retiree, as defined in § 149.2...

  19. Analgesia of Epidural Tramadol in Dogs Submitted to Orchiectomy

    OpenAIRE

    de Almeida, Ricardo Miyasaka; Escobar, André [UNESP; Maguilnik, Samara

    2009-01-01

    Epidural tramadol in veterinary medicine has been studied in only a few instances. In this case, 36 dogs submitted to orchiectomy received 6.0 mg/kg of lidocaine combined with 1.0 mg/kg of tramadol, 0.1 mg/kg of morphine or 0.01 ml/kg of 0.9% NaCl by epidural route. Analgesia was assessed at 4, 8, 12, 18 and 24 hours after surgery. There were no differences between morphine and tramadol over the time of evaluation within these groups, and no complementary analgesia was necessary. In the NaCl ...

  20. Performance of Commercial Laying Hen Submitted to Different Debeaking Methods

    Directory of Open Access Journals (Sweden)

    CH Oka

    Full Text Available ABSTRACT Among the several factors required in breeding laying hens, debeaking is a factor that interferes with batch performance and affects animal welfare. Thus, the objective of this study was to evaluate three different debeaking procedures and to verify the best technique to be used. For this, the performance of the birds, the incidence of cannibalism, and in rearing phase, the quality of the eggs were evaluated. Dekalb White birds were distributed in a completely randomized design with three treatments, T1 (infrared radiation debeaking T2 (hot blade debeaking and T3 (V debeaking.The data was submitted to Analysis of Variance and compared by Tukey’s test (95%, using statistical software R. The frequencies of mortality and cannibalism were submitted to the Chi-Square test (Software R. It was observed that mortality was lower with IR debeaking in the breeding phase. Already in the rearing phase, the mortality was similar between the debeaking techniques and the cannibalism was null. The final mean weight (g, mean weight gain (g and average daily weight gain in the rearing and egg quality variables were higher for V debeaking when compared to other techniques. It is concluded that V-debeaking provides better bird performance, resistance and shell thickness when compared to the infrared radiations and hot blade debeaking, in addition to subjecting the birds to less stress.

  1. Perioperative fasting time among cancer patients submitted to gastrointestinal surgeries

    Directory of Open Access Journals (Sweden)

    Nayara de Castro Pereira

    Full Text Available Abstract OBJECTIVE To identify the length of perioperative fasting among patients submitted to gastrointestinal cancer surgeries. METHOD Retrospective cohort study, developed by consulting the medical records of 128 patients submitted to gastrointestinal cancer surgeries. RESULTS The mean of total length of fasting was 107.6 hours. The total length of fasting was significantly associated with the number of symptoms presented before (p=0.000 and after the surgery (p=0.007, the length of hospital stay (p=0.000, blood transfusion (p=0.013, nasogastric tube (p=0.001 and nasojejunal tube (p=0,003, postoperative admission at ICU (p=0.002, postoperative death (p=0.000 and length of preoperative fasting (p=0.000. CONCLUSION The length of fasting is associated with complications that affect the quality of the patients’ postoperative recovery and nurses’ work. The nursing team should be alert to this aspect and being responsible for overseeing the patients’ interest, should not permit the unnecessary extension of fasting.

  2. Degradation studies on plasticized PVC films submited to gamma radiation

    Directory of Open Access Journals (Sweden)

    Vinhas Glória Maria

    2003-01-01

    Full Text Available Poly (vinyl chloride, PVC, is a rigid polymer and for several of its applications must be compounded with plasticizing agents. The plasticizers minimize the dipolar interactions, which exist between the polymer's chains, promoting their mobility. In this work we studied the properties of PVC/plasticizer systems submitted to different doses of gamma radiation. We have used four commercial plasticizers amongt them di(2-ethylhexyl phthalate, DEHP, which is present in a great number of commercial applications. The PVC/plasticizer systems have been studied as films made by the solvent evaporation technique. Irradiated and non-irradiated films have been characterized by viscosimetric analysis, mechanical essays and infrared spectroscopy. The results have shown that the rigid, non plasticized, PVC film presented the greatest degradation index, while among the plasticized films the one which presented the larger degradation index due to chain scission was the DEHP plasticized PVC.

  3. 30 CFR 285.607 - How do I submit my SAP?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I submit my SAP? 285.607 Section 285.607... Assessment Plan and Information Requirements for Commercial Leases § 285.607 How do I submit my SAP? You must submit one paper copy and one electronic version of your SAP to MMS at the address listed in § 285.110(a). ...

  4. 78 FR 13053 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request...

    Science.gov (United States)

    2013-02-26

    ... Department of Justice for enforcement purposes. Non-confidential business information submitted by... 1033, Subpart F). Estimated number of respondents: 16 (total). Frequency of response: Quarterly...

  5. Perioperative fasting time among cancer patients submitted to gastrointestinal surgeries.

    Science.gov (United States)

    Pereira, Nayara de Castro; Turrini, Ruth Natalia Teresa; Poveda, Vanessa de Brito

    2017-05-25

    To identify the length of perioperative fasting among patients submitted to gastrointestinal cancer surgeries. Retrospective cohort study, developed by consulting the medical records of 128 patients submitted to gastrointestinal cancer surgeries. The mean of total length of fasting was 107.6 hours. The total length of fasting was significantly associated with the number of symptoms presented before (p=0.000) and after the surgery (p=0.007), the length of hospital stay (p=0.000), blood transfusion (p=0.013), nasogastric tube (p=0.001) and nasojejunal tube (p=0,003), postoperative admission at ICU (p=0.002), postoperative death (p=0.000) and length of preoperative fasting (p=0.000). The length of fasting is associated with complications that affect the quality of the patients' postoperative recovery and nurses' work. The nursing team should be alert to this aspect and being responsible for overseeing the patients' interest, should not permit the unnecessary extension of fasting. Identificar la duración del ayuno perioperatorio entre los pacientes sometidos a cirugías de cáncer gastrointestinal. Estudio de cohorte retrospectivo, por consulta de los registros médicos de 128 pacientes sometidos a cirugías de cáncer gastrointestinal. La media de la duración total del ayuno fue de 107,6 horas. La duración total del ayuno se asoció significativamente con el número de síntomas presentados antes (p=0,000) y después de la cirugía (p=0,007), la duración de la estancia hospitalaria (p=0,000), transfusión de sangre (p=0,013),tubo nasogástrico (P=0,003), ingreso postoperatorio en la UCI (p=0,002), muerte postoperatoria (p=0,000) y duración del ayuno preoperatorio (p=0,000). La duración del ayuno se asocia con complicaciones que afectan la calidad de la recuperación postoperatoria de los pacientes y el trabajo de enfermería. El equipo de enfermería debe estar alerta en relación a este aspecto y ser responsable de supervisar el interés de los pacientes, no

  6. Reach capacity in older women submitted to flexibility training

    Directory of Open Access Journals (Sweden)

    Elciana de Paiva Lima Vieira

    2015-11-01

    Full Text Available The aim of this study was to analyze the effect of flexibility training on the maximum range of motion levels and reach capacity of older women practitioners of aquatic exercises of the Prev-Quedas project. Participants were divided into two groups: intervention (IG, n = 25, which were submitted to flexibility training program and control (CG, n = 21, in which older women participated only in aquatic exercises. Flexibility training lasted three months with weekly frequency of two days, consisting of stretching exercises involving trunk and lower limbs performed after aquatic exercises. The stretching method used was passive static. Assessment consisted of the functional reach, lateral and goniometric tests. Statistical analysis was performed using the following tests: Shapiro-Wilk normality, ANCOVA, Pearson and Spearman correlations. Significant results for GI in gains of maximum range of motion for the right hip joint (p = 0.0025, however, the same result was not observed in other joints assessed, and there was no improvement in functional and lateral reach capacity for both groups. Significant correlations between reach capacity and range of motion in the trunk, hip and ankle were not observed. Therefore, flexibility training associated with the practice of aquatic exercises promoted increased maximum range of motion only for the hip joint; however, improvement in the reach capacity was not observed. The practice of aquatic exercises alone did not show significant results.

  7. Brazilian Bentonite Submitted to Mild Acid Treatment Under Moderated Conditions

    Science.gov (United States)

    Andrade, C. G. Bastos; Justo, V. F.; Fermino, D. M.; Valenzuela, M. G. S.; Volzone, C.; Valenzuela-Diaz, F. R.

    The present paper presents the study of light green smectite clay, from Paraiba, Brazil, submitted to mild acid attack under moderated conditions. Usually, clays are subjected to treatment with strong inorganic acids at temperatures near the boiling point and at high acid concentrations and then, widely used as bleaching agents. The treatment occurred under bellow boiling temperature and at short times of reaction (90°C, reaction times of 1, 6, 12, 18 and 24 hours in close reactor, concentration of the aqueous solution of hydrochloric acid 1.5 M, clay/acid solution ratio of 1g/10mL). The purpose of these attacks is to reduce the concentration of impurities providing color, with minimal change in the clay minerals structure, aiming at use in products of high value such as cosmetics and polymer/clay nanocomposites. The raw clay and the attacked samples were characterized by X-ray diffraction (XRD), cation exchange capacity (CEC), stereomicroscopy, scanning electron microscopy (SEM) and energy dispersive X-ray detector (EDS).

  8. Quality of life in patients submitted to radical prostatectomy

    Directory of Open Access Journals (Sweden)

    Débora Moura Miranda Goluart

    2014-09-01

    Full Text Available A cross-sectional study with a descriptive analysis of 81 patients submitted to radical prostatectomy (RP. Our objective was to correlate quality of life (QL according to the EORTC-QLQ C30 with age group and time after surgery. Mean age was 65.7 years. Most sought the care of urology, asymptomatic. Some referred former smoking (49.9% and high blood pressure (53.1%. Mean preoperative SBP was 8.4 ng/ml. Most participants were in stages T2c to T3, Gleason ?6 and over a year after surgery. Erectile dysfunction presented in 90.1%, and urinary incontinence in 33.3%. Functional and overall health scales presented high QL indexes, and symptomatology, with low ones. Older adults presented higher QL regarding emotional functioning, financial difficulties and overall health, as well as those with over a year after surgery, regarding cognitive functioning and fatigue. Although QL was not greatly affected, there were differences between age groups and time after surgery. doi: 10.5216/ree.v16i3.21589.

  9. 34 CFR 35.4 - Administrative claim; evidence and information to be submitted.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Administrative claim; evidence and information to be submitted. 35.4 Section 35.4 Education Office of the Secretary, Department of Education TORT CLAIMS AGAINST...) Death. In support of a claim based on death, the claimant may be required to submit the following...

  10. 32 CFR 1621.2 - Duty to report for and submit to induction.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Duty to report for and submit to induction. 1621... SYSTEM DUTY OF REGISTRANTS § 1621.2 Duty to report for and submit to induction. When the Director of Selective Service orders a registrant for induction, it shall be the duty of the registrant to report for...

  11. 30 CFR 250.285 - How do I submit revised and supplemental EPs, DPPs, and DOCDs?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I submit revised and supplemental EPs... supplemental EPs, DPPs, and DOCDs? (a) Submittal. You must submit to the Regional Supervisor any revisions and supplements to approved EPs, DPPs, or DOCDs for approval, whether you initiate them or the Regional Supervisor...

  12. 75 FR 60404 - Information Collection Request Submitted to Office of Management and Budget

    Science.gov (United States)

    2010-09-30

    ...; ] ADMINISTRATIVE CONFERENCE OF THE UNITED STATES Information Collection Request Submitted to Office of Management... United States will submit an Information Collection Request (ICR) to the Office of Management and Budget (OMB) requesting approval for the following collection of information: 3002-0003, Substitute...

  13. 20 CFR 405.331 - Submitting evidence to an administrative law judge.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Submitting evidence to an administrative law judge. 405.331 Section 405.331 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ADMINISTRATIVE REVIEW PROCESS FOR ADJUDICATING INITIAL DISABILITY CLAIMS Administrative Law Judge Hearing § 405.331 Submitting...

  14. 27 CFR 73.31 - May I submit forms electronically to TTB?

    Science.gov (United States)

    2010-04-01

    ... TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) PROCEDURES AND PRACTICES ELECTRONIC SIGNATURES; ELECTRONIC SUBMISSION OF FORMS Electronic Filing of Documents with TTB § 73.31 May I submit forms electronically to TTB? Yes; you may submit an electronic form, instead of a paper form, to satisfy any reporting...

  15. 27 CFR 73.34 - When is an electronically submitted form considered timely filed?

    Science.gov (United States)

    2010-04-01

    ... AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) PROCEDURES AND PRACTICES ELECTRONIC SIGNATURES; ELECTRONIC SUBMISSION OF FORMS Electronic Filing of Documents with TTB § 73.34 When is an electronically submitted form considered timely filed? If you submit a form to our electronic...

  16. 20 CFR 703.203 - Application for security deposit determination; information to be submitted; other requirements.

    Science.gov (United States)

    2010-04-01

    ... determination; information to be submitted; other requirements. 703.203 Section 703.203 Employees' Benefits... AND RELATED STATUTES INSURANCE REGULATIONS Insurance Carrier Security Deposit Requirements § 703.203 Application for security deposit determination; information to be submitted; other requirements. (a) Each...

  17. 13 CFR 126.303 - Where must a concern submit its application and certification?

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Where must a concern submit its application and certification? 126.303 Section 126.303 Business Credit and Assistance SMALL BUSINESS... certification? A concern seeking certification as a HUBZone SBC must submit either an electronic application to...

  18. 40 CFR 60.2755 - When must I submit my waste management plan?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... waste management plan? You must submit the waste management plan no later than the date specified in... Compliance Times for Commercial and Industrial Solid Waste Incineration Units that Commenced Construction On...

  19. 44 CFR 65.15 - List of communities submitting new technical data.

    Science.gov (United States)

    2010-10-01

    ... Program IDENTIFICATION AND MAPPING OF SPECIAL HAZARD AREAS § 65.15 List of communities submitting new... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false List of communities submitting new technical data. 65.15 Section 65.15 Emergency Management and Assistance FEDERAL EMERGENCY...

  20. 76 FR 28192 - Petition for Rulemaking Submitted by the Nuclear Energy Institute

    Science.gov (United States)

    2011-05-16

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION 10 CFR Part 26 Petition for Rulemaking Submitted by the Nuclear Energy Institute AGENCY: Nuclear... rulemaking (PRM) submitted by Anthony R. Pietrangelo, on behalf of the Nuclear Energy Institute (NEI), the...

  1. 20 CFR 661.430 - Under what conditions may the Governor submit a Workforce Flexibility Plan?

    Science.gov (United States)

    2010-04-01

    ... a Workforce Flexibility Plan? 661.430 Section 661.430 Employees' Benefits EMPLOYMENT AND TRAINING... the Governor submit a Workforce Flexibility Plan? (a) A State may submit to the Secretary, and the Secretary may approve, a workforce flexibility (work-flex) plan under which the State is authorized to waive...

  2. 77 FR 28401 - Information Collection Activities: Legacy Data Verification Process (LDVP); Submitted for Office...

    Science.gov (United States)

    2012-05-14

    ... Verification Process (LDVP); Submitted for Office of Management and Budget (OMB) Review; Comment Request ACTION... comments on a collection of information that we will submit to the Office of Management and Budget (OMB... to January 2000 that do not have an assigned API number. This notice announces our intention to...

  3. 36 CFR 1206.86 - What additional materials must I submit with the final narrative report?

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false What additional materials must I submit with the final narrative report? 1206.86 Section 1206.86 Parks, Forests, and Public... narrative report? You must submit the materials determined by the Commission as found in the NHPRC grant...

  4. Course Factors That Motivate Students to Submit End-of-Course Evaluations

    Science.gov (United States)

    Jaquett, Caroline M.; VanMaaren, Victoria G.; Williams, Robert L.

    2017-01-01

    We surveyed students (N = 152) in several sections of an undergraduate educational psychology course to determine what course factors would most motivate them to submit course evaluations. The survey directed students to choose among several pairs of course characteristics as to their relative impact on their decision to submit a course…

  5. 34 CFR 86.6 - When must an IHE submit a drug prevention program certification?

    Science.gov (United States)

    2010-07-01

    ... ABUSE PREVENTION General § 86.6 When must an IHE submit a drug prevention program certification? (a... each part of its drug prevention program, whether in effect or planned; (ii) Provides a schedule to... 34 Education 1 2010-07-01 2010-07-01 false When must an IHE submit a drug prevention program...

  6. 21 CFR 720.7 - Notification of person submitting cosmetic product ingredient statement.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Notification of person submitting cosmetic product... AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY FILING OF COSMETIC PRODUCT INGREDIENT COMPOSITION STATEMENTS § 720.7 Notification of person submitting cosmetic product ingredient statement. When Form FDA...

  7. 77 FR 25104 - Petition for Rulemaking; Submitted by the Natural Resources Defense Council, Inc.

    Science.gov (United States)

    2012-04-27

    ... COMMISSION 10 CFR Part 50 Petition for Rulemaking; Submitted by the Natural Resources Defense Council, Inc... raised in the petition for rulemaking (PRM), PRM-50-102, submitted by the Natural Resources Defense... the NRC's PDR reference staff at 1-800-397-4209, 301-415-4737, or by email to PDR.resource@nrc.gov...

  8. 78 FR 44034 - Petition for Rulemaking Submitted by the Natural Resources Defense Council, Inc.

    Science.gov (United States)

    2013-07-23

    ...; ] NUCLEAR REGULATORY COMMISSION 10 CFR Part 50 Petition for Rulemaking Submitted by the Natural Resources... issues raised in the petition for rulemaking (PRM), PRM-50-100, submitted by the Natural Resources...- 4209, 301-415-4737, or by email to PDR.Resource@nrc.gov . The ADAMS accession number for each document...

  9. AFRICAN MAHOGANY SUBMITTED TO DRIP IRRIGATION AND FERTILIZATION

    Directory of Open Access Journals (Sweden)

    José Alves Júnior

    Full Text Available ABSTRACT African mahogany (Khaya ivorensis A. Chev. is a tree species that has been increasing in Brazilian commercial planting. However, the lack of water and nutrition are great obstacles for crop production. The aim of this study was to evaluate the growth of young mahogany plants submitted to drip irrigation and topdressing. The experimental design was of randomized blocks, with three repetitions in subdivided plots. Treatments consisted of drippers: 1, 2 and 3plt-1; flows: 2, 4 and 8L h-1, and a treatment without irrigation. For topdressing, subplots levels were, as follows: 1 17.5 and 25.2; 2 35.1 and 50.1; 3 52.5 and 75.0; 4 70.0 and 100.2; and 5 87.5 and 125.1 g plant-1 N and K2O, respectively, divided into five bimonthly applications, which started in the 4th month after planting. Plant height, diameter at root collar and at breast height (DBH, and stem height were evaluated. Results showed statistically significant differences (P>0.05 between irrigated and non-irrigated plants. Mean plant height ranged (from 2 to 20 months in field from 0.33 to 3.25 and 2.67m for irrigated and non-irrigated plants, respectively. Mean stem height ranged from 0.23m to 0.87 and 0.71m for irrigated and non-irrigated plants, respectively. Thus, irrigation with 1 dripper per tree and flow of 2L h-1 was able to supply mahogany water requirements in the first two years in field. Trees have not responded to N and K topdressing at the beginning of the cycle.

  10. Surgical site infection in patients submitted to heart transplantation.

    Science.gov (United States)

    Rodrigues, Jussara Aparecida Souza do Nascimento; Ferretti-Rebustini, Renata Eloah de Lucena; Poveda, Vanessa de Brito

    2016-08-29

    to analyze the occurrence and predisposing factors for surgical site infection in patients submitted to heart transplantation, evaluating the relationship between cases of infections and the variables related to the patient and the surgical procedure. retrospective cohort study, with review of the medical records of patients older than 18 years submitted to heart transplantation. The correlation between variables was evaluated by using Fisher's exact test and Mann-Whitney-Wilcoxon test. the sample consisted of 86 patients, predominantly men, with severe systemic disease, submitted to extensive preoperative hospitalizations. Signs of surgical site infection were observed in 9.3% of transplanted patients, with five (62.5%) superficial incisional, two (25%) deep and one (12.5%) case of organ/space infection. There was no statistically significant association between the variables related to the patient and the surgery. there was no association between the studied variables and the cases of surgical site infection, possibly due to the small number of cases of infection observed in the sample investigated. analisar a ocorrência e os fatores predisponentes para infecção de sítio cirúrgico em pacientes submetidos a transplante cardíaco e verificar a relação entre os casos de infecção e as variáveis referentes ao paciente e ao procedimento cirúrgico. estudo de coorte retrospectivo, com exame dos prontuários médicos de pacientes maiores de 18 anos, submetidos a transplante cardíaco. A correlação entre variáveis foi realizada por meio dos testes exato de Fischer e de Mann-Whitney-Wilcoxon. a amostra foi constituída por 86 pacientes, predominantemente homens, com doença sistêmica grave, submetidos a internações pré-operatórias extensas. Apresentaram sinais de infecção do sítio cirúrgico 9,3% dos transplantados, sendo cinco (62,5%) incisionais superficiais, duas (25%) profundas e um (12,5%) caso de infecção de órgão/espaço. Não houve associa

  11. Transcriptional activation in chondrocytes submitted to hydrostatic pressure.

    Science.gov (United States)

    Sironen, R; Elo, M; Kaarniranta, K; Helminen, H J; Lammi, M J

    2000-01-01

    At present, only a little is known about the transcriptional regulation in chondrocytes submitted to various physicomechanical factors known to exist in articular cartilage. Recently, we have investigated the effects of hydrostatic pressure on transcriptional control in chondrocytes using human chondrosarcoma and immortalized chondrocyte cell lines for the experiments. Hydrostatic pressure was applied on the cells in a special computer-controlled, water-filled pressure chamber, where cyclic and static pressures up to 32 MPa can be created. Differential display RT-PCR and probing of cDNA arrays are the methods we have used to study differential gene expression due to hydrostatic pressure. By differential display RT-PCR experiments, we have observed several differentially expressed cDNA bands under continuous 30 MPa hydrostatic pressure, while 30 MPa cyclic pressure at 1 Hz produced much fewer changes. In the first phase of our studies, we have focused on the effects of 30 MPa hydrostatic pressure because it causes a unique hsp70-mediated stress response in immortalized chondrocytes. Differential display RT-PCR screening provided us with several clones that derive from low-abundance mRNAs, such as death-associated protein 3 (DAP3), a nucleotide-binding protein which increases due to interferon-gamma induced cell death; PTZ-17 (or p311), a seizure-related protein; H-NUC, a nuclear DNA binding protein; and one new gene of unknown function. In Northern blots, an induction was confirmed for the new gene, DAP3 and PTZ-17 were down-regulated in some but not in all parallel experiments; however, basal level of H-NUC mRNA was too low to be detected in Northern blots. We then chose to widen our screening to a number of known genes arrayed as cDNA blots. Under 30 MPa continuous hydrostatic pressure, four different time points were chosen (0, 3, 6 and 24 h) for the experiments. The screening of 588 cDNAs showed 15 up-regulated and 6 down-regulated genes. Consistently with our

  12. Nursing diagnoses and interventions in children submitted to cochlear implantation.

    Science.gov (United States)

    Pereira, Patrícia Juliana Santos; Souza, Natália Fernanda Higa de; Almeida, Raissa Janine de; Menezes, Daiane Cabrera; Bom, Gesiane Cristina; Trettene, Armando Dos Santos

    2017-06-12

    Identifying the main nursing diagnoses and interventions in children submitted to cochlear implant in the immediate postoperative period. A cross-sectional study conducted between February and April 2016, considering nursing history (anamnesis and physical examination) and nursing diagnoses (NANDA - International) with their respective interventions (Nursing Intervention Classification - NIC). Descriptive statistical analysis was used to construct the results. A total of 19 children participated in this study. The main nursing diagnoses listed were: impaired verbal communication, impaired skin integrity, risk for infection, risk for falls, and risk for bleeding (n=19; 100%). Regarding the nursing interventions, the following prevailed: Improvement in communication: auditory deficit, Skin surveillance, Protection against infection, Prevention of falls and Precautions against bleeding (n=19; 100%). Nursing diagnoses and interventions related to the cochlear implant postoperative period were related to communication, bleeding control, surgical wound care, infection prevention, comfort and well-being. Identificar os principais diagnósticos e intervenções de enfermagem em crianças submetidas a implante coclear em pós-operatório imediato. Estudo transversal realizado entre fevereiro e abril de 2016. Foram considerados o histórico de enfermagem (anamnese e exame físico) e os diagnósticos de enfermagem (NANDA - Internacional) com suas respectivas intervenções (Nursing Intervention Classification - NIC). Para construção dos resultados utilizou-se da análise estatística descritiva. Participaram do presente estudo 19 crianças. Os principais diagnósticos de enfermagem elencados foram: Comunicação verbal prejudicada, Integridade da pele prejudicada, Risco de infecção, Risco de queda e Risco de sangramento (n=19; 100%). Quanto às intervenções de enfermagem, prevaleceram: Melhora na comunicação: deficit auditivo, Supervisão da pele, Proteção contra

  13. Glucose metabolism in rats submitted to skeletal muscle denervation

    Directory of Open Access Journals (Sweden)

    Wilton Marlindo Santana Nunes

    2005-07-01

    Full Text Available This study analyzed the local and systemic effects of immobilization by denervation of the skeletal muscle on glucose metabolism. The rats were submitted to section of the right paw sciatic nerve. A reduction was observed in glucose uptake by the isolated soleus muscle of the denervated paw after 3 and 7 days, but not after 28 days in relation to the control animals. There was no difference after 3 and 7 days in glucose uptake by the soleus muscle of the opposite intact paw in relation to the control. There was increased glucose uptake in the same paw 28 days after denervation. The rate of glucose removal in response to exogenous insulin after 28 days of denervation was significantly higher than in control animals and those observed after 3 and 7 days of denervation. These results suggest that immobilization by denervation interfered not only in glucose metabolism in the skeletal muscle involved but also in other tissues.O estudo analisou os efeitos locais e sistêmicos da imobilização por desnervação do músculo esquelético sobre o metabolismo glicidico. Ratos foram submetidos à secção do nervo ciático da pata direita. Observou-se redução da captação de glicose pelo músculo sóleo isolado da pata desnervada após 3 e 7 mas não após 28 dias em relação a animais controle. Não houve diferença após 3 e 7 dias na captação de glicose pelo músculo sóleo da pata contralateral intacta em relação ao controle. Houve aumento da captação de glicose nesta mesma pata 28 dias após a desnervação. A taxa de remoção da glicose em resposta à insulina exógena após 28 dias de desnervação foi significantemente superior à do controle e àquelas observadas após 3 e 7 dias da desnervação. Esses resultados sugerem que a imobilização por desnervação interfere não só no metabolismo da glicose no músculo esquelético envolvido como também em outros tecidos.

  14. Survival of Macrobrachium amazonicum embryos submitted to cooling.

    Science.gov (United States)

    Ferreira, Arthur Vinícius Lourenço; Martins, Moisés Fernandes; Martins de Sousa, Míriam Luzia Nogueira; Soares Filho, Aldeney Andrade; Sampaio, Célia Maria de Souza

    2017-06-01

    Cooling techniques have several applications for reproduction in aquaculture. However, few studies have sought to create protocols for cooling and cryopreservation of Macrobrachium amazonicum embryos. Thus, the objective of this work was to verify the survival of M. amazonicum embryos and the correlation between embryonic volume and mortality of M. amazonicum embryos after cooling. Embryo pools were collected from three females and divided into two treatment groups: dimethyl sulfoxide (DMSO) 3% and ethylene glycol (EG) 0.5%, both of them associated with 2 M sucrose. Positive and negative control groups consisted of seawater 10%. Aliquots of 10 µg of embryos were placed in Falcon® tubes containing a cryoprotectant solution and submitted directly to the test temperature of 2°C for 2 and 6 h of cooling. Further analysis of survival and embryonic volume were performed under a stereoscopic microscope. Data were subjected to analysis of variance (ANOVA), and means were compared using the Tukey test at 5%. The highest embryonic survival rate was observed after the shortest storage time for both the DMSO 3% and the 0.5% EG groups, with survival rates of 84.8 ± 3.9 and 79.7 ± 2.8%, respectively. There was a reduction in survival after 24 h, with the DMSO 3% group presenting a survival rate of 71.7 ± 6.6%, and the EG 0.5% group, 66 ± 6.9%. Survival showed a statistically significant difference when compared with the positive controls after 2 h and 24 h of cooling, with 99 ± 0.5% and 95.8 ± 1.5% survival rates, respectively. There was no significant statistical difference in the embryonic volume, but it was possible to observe a change in the appearance of the embryos, from a translucent coloration to an opaque white or brownish coloration, after 24 h in incubators. Thus, it can be concluded that survival is inversely proportional to storage time and that, although there was no change in the embryonic volume after cooling, a change in the appearance of embryos could

  15. Disfunção sexual em pacientes com câncer do colo uterino avançado submetidas à radioterapia exclusiva Sexual dysfunction in patients with advanced cervical cancer submitted to exclusive radiotherapy

    Directory of Open Access Journals (Sweden)

    Bebiana Calisto Bernardo

    2007-02-01

    Full Text Available OBJETIVO: identificar disfunções sexuais em pacientes com câncer de colo uterino submetidas à radioterapia exclusiva pela técnica de braquiterapia de alta taxa de dose. MÉTODOS: foi realizado um estudo descritivo do tipo corte transversal no período de janeiro a junho de 2004. O estudo envolveu 71 pacientes selecionadas de acordo o perfil estabelecido e que vinham sendo seguidas no ambulatório de pélvis do Hospital do Câncer de Pernambuco. Os dados foram coletados a partir de um questionário estruturado, complementado por um exame ginecológico visando investigar queixas de disfunção sexual após a radioterapia. Foi utilizado o programa estatístico Epi-Info 6.04 para processamento e análise dos dados. A análise descritiva foi feita pela média, mediana, valores máximo e mínimo. Para análise bivariada foram realizados os testes de homogeneidade marginal e McNemar, considerando um nível de significância de 5%. RESULTADOS: das complicações ginecológicas identificadas, destacam-se fibrose, estenose e atrofia vaginais (98,6, 76,1 e 71,8% dos casos, respectivamente. As disfunções sexuais identificadas foram: frigidez e falta de lubrificação, de excitação e de orgasmo, que ocorreram em 76,1% dos casos, falta de libido em 40,8% e vaginismo em 5,6% dos casos. CONCLUSÕES: as disfunções sexuais são freqüentes em pacientes com câncer do colo uterino avançado tratadas com radioterapia exclusiva utilizando o protocolo de braquiterapia de alta taxa de dose. Atenção específica deve ser dada à anamnese sexual e ao exame ginecológico durante o acompanhamento destas pacientes.PURPOSE: to identify sexual dysfunctions in patients with cancer of the uterine cervix submitted to exclusive radiotherapy, using the high dose rate (HDR brachytherapy technique. METHODS: a descriptive transversal study from January to June of 2004. The study involved 71 selected patients who had been followed in the pelvis outpatient clinic from the

  16. 21 CFR 803.40 - If I am an importer, what kinds of individual adverse event reports must I submit, when must I...

    Science.gov (United States)

    2010-04-01

    ... adverse event reports must I submit, when must I submit them, and to whom must I submit them? 803.40... (CONTINUED) MEDICAL DEVICES MEDICAL DEVICE REPORTING Importer Reporting Requirements § 803.40 If I am an importer, what kinds of individual adverse event reports must I submit, when must I submit them, and to...

  17. Common statistical and research design problems in manuscripts submitted to high-impact medical journals.

    Science.gov (United States)

    Fernandes-Taylor, Sara; Hyun, Jenny K; Reeder, Rachelle N; Harris, Alex Hs

    2011-08-19

    To assist educators and researchers in improving the quality of medical research, we surveyed the editors and statistical reviewers of high-impact medical journals to ascertain the most frequent and critical statistical errors in submitted manuscripts. The Editors-in-Chief and statistical reviewers of the 38 medical journals with the highest impact factor in the 2007 Science Journal Citation Report and the 2007 Social Science Journal Citation Report were invited to complete an online survey about the statistical and design problems they most frequently found in manuscripts. Content analysis of the responses identified major issues. Editors and statistical reviewers (n = 25) from 20 journals responded. Respondents described problems that we classified into two, broad themes: A. statistical and sampling issues and B. inadequate reporting clarity or completeness. Problems included in the first theme were (1) inappropriate or incomplete analysis, including violations of model assumptions and analysis errors, (2) uninformed use of propensity scores, (3) failing to account for clustering in data analysis, (4) improperly addressing missing data, and (5) power/sample size concerns. Issues subsumed under the second theme were (1) Inadequate description of the methods and analysis and (2) Misstatement of results, including undue emphasis on p-values and incorrect inferences and interpretations. The scientific quality of submitted manuscripts would increase if researchers addressed these common design, analytical, and reporting issues. Improving the application and presentation of quantitative methods in scholarly manuscripts is essential to advancing medical research.

  18. 14 CFR 193.5 - How may I submit safety or security information and have it protected from disclosure?

    Science.gov (United States)

    2010-01-01

    ... SUBMITTED INFORMATION § 193.5 How may I submit safety or security information and have it protected from... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false How may I submit safety or security information and have it protected from disclosure? 193.5 Section 193.5 Aeronautics and Space FEDERAL AVIATION...

  19. 78 FR 42085 - Draft Guidance for Industry on Pediatric Study Plans: Content of and Process for Submitting...

    Science.gov (United States)

    2013-07-15

    ...: Content of and Process for Submitting Initial Pediatric Study Plans and Amended Pediatric Study Plans... Plans: Content of and Process for Submitting Initial Pediatric Study Plans and Amended Pediatric Study... draft guidance for industry entitled ``Pediatric Study Plans: Content of and Process for Submitting...

  20. 77 FR 74019 - Public Information Collection Requirements Submitted to the Office of Management and Budget (OMB...

    Science.gov (United States)

    2012-12-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Medicare & Medicaid Services Public Information Collection Requirements Submitted to the Office of Management and Budget (OMB); Correction AGENCY: Centers for Medicare & Medicaid...

  1. 75 FR 9877 - Public Information Collection Requirement Submitted to Office of Management and Budget (OMB) for...

    Science.gov (United States)

    2010-03-04

    ... From the Federal Register Online via the Government Publishing Office COMMODITY FUTURES TRADING COMMISSION Public Information Collection Requirement Submitted to Office of Management and Budget (OMB) for Review AGENCY: Commodity Futures Trading Commission. ACTION: Notice of Submission of Information...

  2. 77 FR 52035 - Public Information Collection Requirements Submitted to the Office of Management and Budget (OMB...

    Science.gov (United States)

    2012-08-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Medicare & Medicaid Services Public Information Collection Requirements Submitted to the Office of Management and Budget (OMB); Correction AGENCY: Centers for Medicare & Medicaid...

  3. 77 FR 60714 - Information Collection Activities: Legacy Data Verification Process (LDVP); Submitted for Office...

    Science.gov (United States)

    2012-10-04

    ... the information. The subject of this information collection request is the ``Legacy Data Verification... Bureau of Safety and Environmental Enforcement Information Collection Activities: Legacy Data Verification Process (LDVP); Submitted for Office of Management and Budget (OMB) Review; Comment Request ACTION...

  4. 78 FR 56225 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request; Soil...

    Science.gov (United States)

    2013-09-12

    ... AGENCY Information Collection Request Submitted to OMB for Review and Approval; Comment Request; Soil...) for review and approval in accordance with the Paperwork Reduction Act: ``Soil Fumigant Risk... measures necessary for reregistration eligibility for certain soil fumigant chemicals are adequately...

  5. Dosimetry of patients submitted to cerebral PET/CT for the diagnosis of mild cognitive impairment

    Energy Technology Data Exchange (ETDEWEB)

    Santana, Priscila do Carmo; Oliveira, Paulo Marcio Campos de; Bernardes, Felipe Dias; Mamede, Marcelo, E-mail: pridili@gmail.com [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil); Mourao, Arnaldo Prata [Centro Federal de Educacao Tecnologica de Minas Gerais (CEFET), Belo Horizonte, MG (Brazil); Silva, Teogenes Augusto da [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2014-11-15

    Objective: the present study was aimed at evaluating the effective radiation dose in patients submitted to PET/CT for the diagnosis of mild cognitive impairment. Materials and methods: TLD-100 detectors inserted into an Alderson Rando® anthropomorphic phantom were utilized to measure the absorbed dose coming from the CT imaging modality. The anthropomorphic phantoms (male and female adult versions) were submitted to the same technical protocols for patients’ images acquisition. The absorbed dose resulting from the radiopharmaceutical injection was estimated by means of the model proposed by the ICRP publication 106. Results: the effective dose in patients submitted to this diagnostic technique was approximately (5.34 ± 1.99) mSv. Conclusion: optimized protocols for calculation of radioactive activity injected into patients submitted to this diagnostic technique might contribute to reduce the effective radiation dose resulting from PET/CT in the diagnosis of mild cognitive impairment. (author)

  6. 78 FR 72079 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request...

    Science.gov (United States)

    2013-12-02

    ...; Restructuring of the Stationary Source Audit Program (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: The Environmental Protection Agency has submitted an information collection... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION...

  7. 42 CFR 102.60 - Documentation an eligible requester seeking medical benefits must submit.

    Science.gov (United States)

    2010-10-01

    ... HUMAN SERVICES VACCINES SMALLPOX COMPENSATION PROGRAM Required Documentation for Eligible Requesters To... must submit an itemized statement from each health care entity (e.g., clinic, hospital, doctor, or...

  8. Privacy Act System of Records: Invention Reports Submitted to the EPA, EPA-38

    Science.gov (United States)

    Learn about the Invention Reports Submitted to the EPA System, including who is covered in the system, the purpose of data collection, routine uses for the system's records, and other security procedures.

  9. 78 FR 19260 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request...

    Science.gov (United States)

    2013-03-29

    ... additional information about EPA's public docket, visit http://www.epa.gov/dockets . Abstract: EPA will... current members in the party classes are to submit updates and corrections to their current registration...

  10. Summary of Country Reports Submitted to the Energy Efficiency Working Party: October 2011

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The purpose of this summary report is to highlight energy efficiency policy action and planning in IEA member countries submited to the Energy Efficiency Working Party (EEWP) from March to September 2011.

  11. Request for Available Information on Chlorinated Paraffins Submitted as Pre-Manufacture Notices (PMNs)

    Science.gov (United States)

    EPA is requesting new available data on certain chlorinated paraffins in different industries and for different uses, to inform the risk assessments for chlorinated paraffins submitted as Toxic Substances Control Act (TSCA) Premanufacture Notices (PMNs).

  12. 44 CFR 65.4 - Right to submit new technical data.

    Science.gov (United States)

    2010-10-01

    ... a right to request changes to any of the information shown on an effective map that does not impact... community (CEO) or an official designated by the CEO. Should the CEO refuse to submit such a request on...

  13. 78 FR 43880 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request; Notice...

    Science.gov (United States)

    2013-07-22

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Information Collection Request Submitted to OMB for Review and Approval; Comment Request; Notice of Supplemental Distribution of a Registered Pesticide Product AGENCY: Environmental Protection...

  14. Submitting Canine Blood for Prothrombin Time and Partial Thromboplastin Time Determinations

    OpenAIRE

    Smalko, Donna; Johnstone, Ian B.; Crane, Stewart

    1985-01-01

    Practitioners commonly submit samples from dogs for partial thromboplastin time and prothrombin time determinations. Controversy exists as to the necessity for rapid separation of plasma and cells, and submission of the plasma on ice (or frozen). The purpose of this study was to address three questions. First, is it better to submit plasma or is whole blood satisfactory? Second, is it necessary to refrigerate the sample or is maintenance at room temperature (20° C) adequate? Third, does the s...

  15. Peripheral dose measurement in breast cancer patients submitted to Tomotherapy using thermoluminescent dosimeters

    Energy Technology Data Exchange (ETDEWEB)

    Medina A, O.; Medrano S, A. C.; Azorin N, J. [Universidad Autonoma Metropolitana, Unidad Iztapalapa, Av. San Rafael Atlixco 186, Col. Vicentina, 09340 Mexico D. F. (Mexico); Mora G, L. C., E-mail: omedina@xanum.uam.mx [IMSS, Centro Medico Nacional Siglo XXI, Av. Cuauhtemoc 330, 06725 Mexico D. F. (Mexico)

    2015-10-15

    Full text: Thermoluminescence dosimetry (TLD) has been one of the most important techniques in medical radiation applications over many years, creating opportunities of advancing in novel radiotherapy techniques particularly in Tomotherapy with photons. LiF:Mg,Ti TLD is one kind of TLD which can be used in Tomotherapy because of having suitable properties such as good sensitivity, small size and tissue equivalence. Hypo fractionation is a radiotherapeutic technique, widely accepted as an important treatment for breast cancer patients, characterized by high doses at which they are exposed for treatment of cancerous tumors that are irradiated precisely with photons from a helical accelerator and aims to decrease the number of sessions from 3 - 6 weeks to 1 - 3 weeks. Results of measuring the peripheral dose (Pd) in breast cancer patients submitted to Tomotherapy with high-energy photons are presented. (Author)

  16. GUIDELINES: Submitted by the SAGES | SAGES | South African ...

    African Journals Online (AJOL)

    South African Gastroenterology Review. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Vol 5, No 2 (2007) >. Log in or Register to get access to full text downloads.

  17. Supplementation with vitamin A enhances oxidative stress in the lungs of rats submitted to aerobic exercise.

    Science.gov (United States)

    Gasparotto, Juciano; Petiz, Lyvia Lintzmaier; Girardi, Carolina Saibro; Bortolin, Rafael Calixto; de Vargas, Amanda Rodrigues; Henkin, Bernardo Saldanha; Chaves, Paloma Rodrigues; Roncato, Sabrina; Matté, Cristiane; Zanotto-Filho, Alfeu; Moreira, José Cláudio Fonseca; Gelain, Daniel Pens

    2015-12-01

    Exercise training induces reactive oxygen species production and low levels of oxidative damage, which are required for induction of antioxidant defenses and tissue adaptation. This process is physiological and essential to improve physical conditioning and performance. During exercise, endogenous antioxidants are recruited to prevent excessive oxidative stress, demanding appropriate intake of antioxidants from diet or supplements; in this context, the search for vitamin supplements that enhance the antioxidant defenses and improve exercise performance has been continuously increasing. On the other hand, excess of antioxidants may hinder the pro-oxidant signals necessary for this process of adaptation. The aim of this study was to investigate the effects of vitamin A supplementation (2000 IU/kg, oral) upon oxidative stress and parameters of pro-inflammatory signaling in lungs of rats submitted to aerobic exercise (swimming protocol). When combined with exercise, vitamin A inhibited biochemical parameters of adaptation/conditioning by attenuating exercise-induced antioxidant enzymes (superoxide dismutase and glutathione peroxidase) and decreasing the content of the receptor for advanced glycation end-products. Increased oxidative damage to proteins (carbonylation) and lipids (lipoperoxidation) was also observed in these animals. In sedentary animals, vitamin A decreased superoxide dismutase and increased lipoperoxidation. Vitamin A also enhanced the levels of tumor necrosis factor alpha and decreased interleukin-10, effects partially reversed by aerobic training. Taken together, the results presented herein point to negative effects associated with vitamin A supplementation at the specific dose here used upon oxidative stress and pro-inflammatory cytokines in lung tissues of rats submitted to aerobic exercise.

  18. Fluid heating system (SAF®): effects on clinical and biochemistry parameters in dogs submitted to inhalatory anesthesia

    OpenAIRE

    Atayde, Ingrid Bueno; Franco, Leandro Guimarães; Silva,Marco Augusto Machado; Soares, Lorena Karine; Bittencourt, João Bosco; Fioravanti, Maria Clorinda Soares; Borges, Alinne Cardoso; Silva,Luiz Antônio Franco da

    2009-01-01

    PURPOSE: To evaluate and describe immediate effects of the infusion of saline solution heated by SAF® in bitches submitted to halothane anesthesia. METHODS: Thirteen bitches were employed and submitted to elective ovariohysterectomy in acclimatized operating room at 22ºC, allocated in two groups: GI, which received non-heated fluid and GII, which received fluid heated at 37ºC by SAF®. The following parameters were evaluated in 30-minutes intervals (M0, M30, M60 and M90): rectal and cutaneous ...

  19. Dental anomalies in children submitted to antineoplastic therapy

    Directory of Open Access Journals (Sweden)

    Camila Merida Carrillo

    2014-06-01

    Full Text Available Cancer is the third most frequent cause of death in children in Brazil. Early diagnosis and medical advances have significantly improved treatment outcomes, which has resulted in higher survival rates and the management of late side effects has become increasingly important in caring for these patients. Dental abnormalities are commonly observed as late effects of antineoplastic therapy in the oral cavity. The incidence and severity of the dental abnormalities depend on the child's age at diagnosis and the type of chemotherapeutic agent used, as well as the irradiation dose and area. The treatment duration and aggressivity should also be considered. Disturbances in dental development are characterized by changes in shape, number and root development. Enamel anomalies, such as discoloration, opacities and hypoplasia are also observed in these patients. When severe, these abnormalities can cause functional and esthetic sequelae that have an impact on the children's and adolescents' quality of life. General dentists and pediatric dentists should understand these dental abnormalities and how to identify them aiming for early diagnosis and appropriate treatment.

  20. 78 FR 43886 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2013-07-22

    ... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public... the leading causes of death and disability in the United States, accounting for seven of every ten..., resources, partnerships, strategies, and progress toward meeting objectives. Awardees will use the...

  1. 78 FR 70300 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2013-11-25

    ... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public... disease. Domains 3 and 4 include interventions that strengthen systems and resources for early detection... information will be collected and tracked to assure proper disbursement of, and accounting for, funds awarded...

  2. 78 FR 43885 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2013-07-22

    ... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public... the leading causes of death and disability in the United States, accounting for seven of every ten..., resources, partnerships, strategies, and progress toward meeting objectives. Awardees will use the...

  3. 76 FR 76165 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2011-12-06

    ... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public... States, accounting for seven of every ten deaths and affecting the quality of life of 90 million... plan, objectives, activities, partnerships, resources, and progress. CDC plans to collect the required...

  4. 76 FR 33305 - Public Information Collection Requirements Submitted to the Office of Management and Budget (OMB...

    Science.gov (United States)

    2011-06-08

    ... HUMAN SERVICES Centers for Medicare & Medicaid Services Public Information Collection Requirements Submitted to the Office of Management and Budget (OMB); Correction AGENCY: Centers for Medicare & Medicaid... Requirements (45 CFR Part 154)'' that was published in the Federal Register on June 1, 2011 (76 FR 31613). FOR...

  5. 78 FR 4413 - Public Information Collection Requirements Submitted to the Office of Management and Budget (OMB...

    Science.gov (United States)

    2013-01-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Medicare & Medicaid Services Public Information Collection Requirements Submitted to the Office of Management and Budget (OMB); Extension of Comment Period AGENCY: Centers for...

  6. A brief history of and an analysis of manuscripts submitted to West ...

    African Journals Online (AJOL)

    A brief history of and an analysis of manuscripts submitted to West African. Journal of Medicine. June 2001 —- May 2002. *0. G. Ajao ... 1978 under the title of “West African Medical Journal and. Nigerian Medical and Dental Practitioner”. .... Abuja State House Clinic l(0.5%) 0. LUTH, Lagos 3(1.5%) l(l.l%). Nigerian lnstitute of.

  7. 76 FR 34995 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2011-06-15

    ... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public... techniques or other forms of information technology. Written comments should be received within 60 days of... Intervention. The overall goal of this study component is to describe relationships among mode of cessation...

  8. 22 CFR 304.4 - Administrative claim; evidence and information to be submitted.

    Science.gov (United States)

    2010-04-01

    ... and the claimant is self-employed, documentary evidence showing the amount of earnings actually lost... any diminished earning capacity. In addition, the claimant may be required to submit to a physical or..., a written statement from his employer showing actual time lost from employment, whether he is a full...

  9. 24 CFR 17.4 - Administrative claim; evidence and information to be submitted.

    Science.gov (United States)

    2010-04-01

    ...-employed, documentary evidence showing the amount of earnings actually lost; (6) Any other evidence or... earning capacity. In addition, the claimant may be required to submit to a physical or mental examination... from his employer showing actual time lost from employment, whether he is a full- or part-time employee...

  10. 77 FR 42181 - Polychlorinated Biphenyls (PCBs); Disposition of Request Submitted Under TSCA Section 21

    Science.gov (United States)

    2012-07-18

    .... SUMMARY: This document announces EPA's reasons for denying a request submitted by the Basel Action Network... visible at all times in the building and returned upon departure. II. Overview On April 11, 2012, EPA received a request from the Basel Action Network, the Sierra Club, and the Center for Biological Diversity...

  11. 77 FR 60333 - Verification of Statements of Account Submitted by Cable Operators and Satellite Carriers

    Science.gov (United States)

    2012-10-03

    ... Copyright Office 37 CFR Part 201 Verification of Statements of Account Submitted by Cable Operators and... Statements of Account and royalty payments that are deposited with the Office by cable operators and... request for comments concerning a new regulation that will allow copyright owners to audit the Statements...

  12. 78 FR 23766 - Proposed Data Collections Submitted for Extension of Public Comment Period

    Science.gov (United States)

    2013-04-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Extension of Public Comment Period Proposed Project Assessment and Monitoring of Breastfeeding-Related...

  13. 20 CFR 10.336 - What are the time frames for submitting bills?

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false What are the time frames for submitting bills? 10.336 Section 10.336 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF...' COMPENSATION ACT, AS AMENDED Medical and Related Benefits Medical Bills § 10.336 What are the time frames for...

  14. 75 FR 36120 - Proposed Information Collection Request Submitted for Public Comment and Recommendations; Program...

    Science.gov (United States)

    2010-06-24

    ... abandoned or deactivated coal mines, notification by the operator; requirements). Once submitted and... Coal Mines) ACTION: Notice. SUMMARY: The Department of Labor, as part of its continuing effort to... underground or in places where there is a fire or explosion hazard. Under the Mine Act and Sec. 75.1702, coal...

  15. 75 FR 57826 - Notice of Public Meeting and Opportunity To Submit Written Comments Concerning the Administration...

    Science.gov (United States)

    2010-09-22

    ... of Public Meeting and Opportunity To Submit Written Comments Concerning the Administration's Review... Guidelines for Multinational Enterprises (MNE), is soliciting written comments and will hold a public meeting concerning the Administration's review of the U.S. NCP. The key question is whether the current structure and...

  16. 30 CFR 210.102 - What production reports must I submit?

    Science.gov (United States)

    2010-07-01

    ... MANAGEMENT FORMS AND REPORTS Production Reports-Oil and Gas § 210.102 What production reports must I submit? (a) Form MMS-4054, Oil and Gas Operations Report. If you operate a Federal or Indian onshore or OCS oil and gas lease or federally approved unit or communitization agreement that contains one or more...

  17. 75 FR 53310 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2010-08-31

    ...., community-associated C. difficile cases) sites will administer a health interview. Remnant stool specimens from cases testing positive for C. difficile toxin will be submitted to reference laboratories for... 15 minutes. An estimated total of 500 CDI Surveillance Health Interviews (HI) will need to be...

  18. 21 CFR 803.20 - How do I complete and submit an individual adverse event report?

    Science.gov (United States)

    2010-04-01

    ... Requirements for Individual Adverse Event Reports § 803.20 How do I complete and submit an individual adverse... individual reports of adverse events. If you are a health professional or consumer, you may use the FDA Form...) If you are a user facility, importer, or manufacturer, you do not have to report an adverse event if...

  19. 77 FR 28375 - Adequacy Status of the Submitted 2008 and 2022 VOC and NOX

    Science.gov (United States)

    2012-05-14

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Adequacy Status of the Submitted 2008 and 2022 VOC and NOX Motor Vehicle Emissions Budgets for... VOC (tons per NOX (tons per summer day) summer day) Year 2008 MVEBs for the Boston- 17.8 37.2...

  20. Effect on osmotic fragility of red blood cells of whole blood submitted ...

    African Journals Online (AJOL)

    Whole body vibration (WBV) exercises in oscillating platforms (OP) have emerged in sports and in the rehabilitation procedures of clinical disorders. The aim of this work was to verify the effects of vibrations on the osmotic fragility (OF) of red blood cells (RBC) isolated from whole blood submitted to OP. Heparinized blood ...

  1. 76 FR 70484 - Agency Information Collection Activities: Submitted for Office of Management and Budget Review...

    Science.gov (United States)

    2011-11-14

    ... Office of Natural Resources Revenue Agency Information Collection Activities: Submitted for Office of Management and Budget Review; Comment Request AGENCY: Office of Natural Resources Revenue, Interior. ACTION... beneficiaries. The ONRR performs the minerals revenue management functions for the Secretary and assists the...

  2. 77 FR 12612 - Agency Information Collection Activities: Submitted for Office of Management and Budget Review...

    Science.gov (United States)

    2012-03-01

    ... Office of Natural Resources Revenue Agency Information Collection Activities: Submitted for Office of Management and Budget Review; Comment Request AGENCY: Office of Natural Resources Revenue, Interior. ACTION... the minerals revenue management functions for the Secretary and assists the Secretary in carrying out...

  3. 76 FR 70486 - Agency Information Collection Activities: Submitted for Office of Management and Budget Review...

    Science.gov (United States)

    2011-11-14

    ... Office of Natural Resources Revenue Agency Information Collection Activities: Submitted for Office of Management and Budget Review; Comment Request AGENCY: Office of Natural Resources Revenue, Interior. ACTION... information from Indian beneficiaries. The ONRR performs the minerals revenue management functions for the...

  4. 76 FR 46651 - Petition for Rulemaking Submitted by the California Association of Marriage and Family Therapists

    Science.gov (United States)

    2011-08-03

    ... COMMISSION 10 CFR Part 26 Petition for Rulemaking Submitted by the California Association of Marriage and... Riemersma, on behalf of the California Association of Marriage and Family Therapists (the petitioner... the Code of Federal Regulations (10 CFR) 26.187(b) to add marriage and family therapists as substance...

  5. 42 CFR 137.132 - How does the Indian Tribe submit a final offer?

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false How does the Indian Tribe submit a final offer? 137.132 Section 137.132 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Final Offer § 137...

  6. 42 CFR 137.131 - When should a final offer be submitted?

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false When should a final offer be submitted? 137.131 Section 137.131 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Final Offer § 137.131 When should...

  7. 27 CFR 73.32 - May I electronically sign forms I submit electronically to TTB?

    Science.gov (United States)

    2010-04-01

    ... AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) PROCEDURES AND PRACTICES ELECTRONIC SIGNATURES; ELECTRONIC SUBMISSION OF FORMS Electronic Filing of Documents with TTB § 73.32 May I electronically sign forms I submit electronically to TTB? You may electronically sign the electronic form you...

  8. 17 CFR 232.311 - Documents submitted in paper under cover of Form SE.

    Science.gov (United States)

    2010-04-01

    ... section, may be filed up to six business days prior to, or on the date of filing of, the electronic format... EXCHANGE COMMISSION REGULATION S-T-GENERAL RULES AND REGULATIONS FOR ELECTRONIC FILINGS Preparation of Electronic Submissions § 232.311 Documents submitted in paper under cover of Form SE. Form SE (§§ 239.64, 249...

  9. 78 FR 63501 - Request To Submit a Two-Part Application-Northwest Medical Isotopes, LLC

    Science.gov (United States)

    2013-10-24

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Request To Submit a Two-Part Application--Northwest Medical Isotopes, LLC AGENCY: Nuclear...-99 and its decay product, technetium-99m, in nuclear medicine procedures. Northwest Medical Isotopes...

  10. 20 CFR 429.104 - What evidence do I need to submit with my claim?

    Science.gov (United States)

    2010-04-01

    ... claim? 429.104 Section 429.104 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ADMINISTRATIVE CLAIMS... evidence or information: (1) A written report from your attending physician or dentist setting forth the... required to submit to a physical or mental examination by a physician employed or designated by SSA. If you...

  11. 40 CFR 63.1574 - What notifications must I submit and when?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 12 2010-07-01 2010-07-01 true What notifications must I submit and..., Catalytic Reforming Units, and Sulfur Recovery Units Notifications, Reports, and Records § 63.1574 What... incinerator-waste heat boiler to burn the exhaust gases from a catalyst regenerator. (iv) Procedures and...

  12. 77 FR 42314 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2012-07-18

    ... culture at that mine. Data collection for this project had previously taken place between the dates of... previous data collection, some trends are beginning to emerge. These include safety culture characteristic... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public...

  13. 34 CFR 461.10 - What documents must a State submit to receive a grant?

    Science.gov (United States)

    2010-07-01

    ... BASIC GRANT PROGRAM How Does a State Apply for a Grant? § 461.10 What documents must a State submit to... fund accounting procedures as may be necessary to ensure proper disbursement of, and accounting for... adult basic education programs, including programs for adults with limited English proficiency, will not...

  14. Infection by Cryptosporidium parvum in renal patients submitted to renal transplant or hemodialysis

    Directory of Open Access Journals (Sweden)

    Chieffi Pedro Paulo

    1998-01-01

    Full Text Available The frequency of infection by Cryptosporidium parvum was determined in two groups of renal patients submitted to immunosuppression. One group consisted of 23 renal transplanted individuals, and the other consisted of 32 patients with chronic renal insufficiency, periodically submitted to hemodialysis. A third group of 27 patients with systemic arterial hypertension, not immunosuppressed, was used as control. During a period of 18 months all the patients were submitted to faecal examination to detect C. parvum oocysts, for a total of 1 to 6 tests per patient. The results showed frequencies of C. parvum infection of 34.8%, 25% and 17.4%, respectively, for the renal transplanted group, the patients submitted to hemodialysis and the control group. Statistical analysis showed no significant differences among the three groups even though the frequency of C. parvum infection was higher in the transplanted group. However, when the number of fecal samples containing C. parvum oocysts was taken in account, a significantly higher frequency was found in the renal transplanted group.

  15. 30 CFR 254.53 - Submitting a response plan developed under State requirements.

    Science.gov (United States)

    2010-07-01

    ...) Identify a qualified individual and require immediate communication between that person and appropriate... you submitted the plan to the State; (5) If the plan received formal approval, the name of the approving organization, the date of approval, and a copy of the State agency's approval letter if one was...

  16. Analysis of final year DVM research projects submitted to the Faculty ...

    African Journals Online (AJOL)

    This study analyzed the intellectual output of the undergraduate final year students. research projects submitted to the Faculty of Veterinary Medicine, Usmanu Danfodiyo University, Sokoto, from 1994 to 2004. The findings of the study show that a total of 194 research projects were produced within the period under study.

  17. 76 FR 18554 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2011-04-04

    ...-New-National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), Centers for... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public... for Disease Control and Prevention (CDC) will publish periodic summaries of proposed projects. To...

  18. 77 FR 40888 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2012-07-11

    ...)--Reinstatement with change--National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public... for Disease Control and Prevention (CDC) will publish periodic summaries of proposed projects. To...

  19. 75 FR 20849 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2010-04-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public... indicated. Other variables for segmentation may include, but not be limited to, geography, language, and...

  20. 78 FR 33094 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2013-06-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public... geography, population size, or urbanicity. Fourth, this information can help guide communities in their...

  1. 78 FR 12772 - Information Collection Activities: Oil and Gas Production Requirements; Submitted for Office of...

    Science.gov (United States)

    2013-02-25

    ... Requirements; Submitted for Office of Management and Budget (OMB) Review; Comment Request ACTION: 30-day Notice... Federal Oil and Gas Royalty Management Act (FOGRMA), 30 U.S.C. 1751(a), grants authority to the Secretary.... 108, we revised what read `API @ 60 F' to now read as `API @ 14.73 PSI & 60 F'; and in Block No. 109...

  2. 78 FR 41059 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request...

    Science.gov (United States)

    2013-07-09

    .... 2060-0297) to the Office of Management and Budget (OMB) for review and approval in accordance with the... American Petroleum Institute (API), represents most of the manufacturers of baseline gasoline, baseline.... Voluminous Tier 1 data for gasoline and diesel fuel were submitted by API and others in 1997. Tier 1 data...

  3. 76 FR 81960 - Agency Information Collections Activities: Submitted for Office of Management and Budget (OMB...

    Science.gov (United States)

    2011-12-29

    ... metals. This information will help guide future water-supply development and well- water testing. It will... other trace metals in Private Bedrock Wells of south-eastern New Hampshire. DATES: You must submit... the number of private wells containing raw-water concentrations of uranium and other trace metals...

  4. 34 CFR 86.4 - What are the procedures for submitting a drug prevention program certification?

    Science.gov (United States)

    2010-07-01

    ... Education DRUG AND ALCOHOL ABUSE PREVENTION General § 86.4 What are the procedures for submitting a drug...-0522) (Authority: 20 U.S.C. 1145g) [55 FR 33581, Aug. 16, 1990, as amended at 61 FR 66226, Dec. 17...

  5. 77 FR 11544 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2012-02-27

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public.... Multi-component approaches may include a combination of clinic services, sexuality education programs...

  6. 24 CFR 3.225 - Educational institutions eligible to submit transition plans.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Educational institutions eligible to submit transition plans. 3.225 Section 3.225 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR...

  7. 40 CFR 60.2195 - What information must I submit prior to initial startup?

    Science.gov (United States)

    2010-07-01

    ... initial startup? 60.2195 Section 60.2195 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY..., 2001 Recordkeeping and Reporting § 60.2195 What information must I submit prior to initial startup? You... startup. (a) The type(s) of waste to be burned. (b) The maximum design waste burning capacity. (c) The...

  8. 40 CFR 60.2953 - What information must I submit prior to initial startup?

    Science.gov (United States)

    2010-07-01

    ... initial startup? 60.2953 Section 60.2953 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... initial startup? You must submit the information specified in paragraphs (a) through (e) of this section prior to initial startup. (a) The type(s) of waste to be burned. (b) The maximum design waste burning...

  9. 77 FR 52341 - Information Collection Activity: Subpart C, Pollution Prevention and Control; Submitted for...

    Science.gov (United States)

    2012-08-29

    ... fishing caused by OCS oil and gas exploration, development, and production activities; The lessee or... Trash and Debris (Sec. 250.300) that was inadvertently submitted under BOEM. Once OMB approves this ICR... Respondents: Potential respondents comprise Federal oil, gas, or sulphur lessees and/or operators. Estimated...

  10. 30 CFR 250.468 - What well records am I required to submit?

    Science.gov (United States)

    2010-07-01

    ... OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Drilling Operations... drilling operations in the GOM OCS Region, you must submit form MMS-133, Well Activity Report, to the District Manager on a weekly basis. (c) For drilling operations in the Pacific or Alaska OCS Regions, you...

  11. 76 FR 28191 - Petition for Rulemaking Submitted by Mr. Erik Erb and 91 Cosigners

    Science.gov (United States)

    2011-05-16

    ... rulemaking (PRM) submitted by Erik Erb, the petitioner, and 91 cosigners, in the planned ``Quality Control... publicly available documents related to the petition using the following methods: NRC's Public Document... in accessing the documents located in ADAMS, contact the NRC's PDR reference staff at 1-800-397-4209...

  12. 78 FR 56226 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request; Motor...

    Science.gov (United States)

    2013-09-12

    ...), Motor Vehicle and Engine Compliance Program Fees (Renewal) (EPA ICR No.2080.05, OMB Control No. 2060... AGENCY Information Collection Request Submitted to OMB for Review and Approval; Comment Request; Motor... to respond to a collection of information unless it displays a currently valid OMB control number...

  13. 37 CFR 2.54 - Requirements for drawings submitted on paper.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Requirements for drawings submitted on paper. 2.54 Section 2.54 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN TRADEMARK CASES Drawing § 2.54 Requirements for...

  14. 75 FR 48346 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2010-08-10

    ... diseases, cholera and other vibrio illnesses, Listeria, babesiosis, brucellosis, Harmful Algal Bloom... Possible Human Rabies Patient Info 50 1 15/60 13 Waterborne Diseases Outbreak Form 57 1 20/60 19 Cholera... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public...

  15. 30 CFR 250.288 - When and how must I submit the Conceptual Plan?

    Science.gov (United States)

    2010-07-01

    ... you have decided on the general concept(s) for development and before you begin engineering design of... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When and how must I submit the Conceptual Plan? 250.288 Section 250.288 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR...

  16. 78 FR 70302 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2013-11-25

    ...) plans to continue to assess its customers' satisfaction with the content, quality and relevance of the... usefulness, general satisfaction with available services and products, and suggestions for improvement of... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public...

  17. 76 FR 51981 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2011-08-19

    ... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public... because of a false sense of improvement in the occupational injury rates. It also increases the misdirection of scarce safety and health resources because hazardous workplaces are not appropriately...

  18. 77 FR 65893 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2012-10-31

    ..., smallpox, typhus, or yellow fever or having been exposed to any such disease is in the incubation period... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public... for Disease Control and Prevention (CDC) will publish periodic summaries of proposed projects. To...

  19. 40 CFR 63.7550 - What reports must I submit and when?

    Science.gov (United States)

    2010-07-01

    ... fuel, you must submit the calculation of TSM input, using Equation 6 of § 63.7530, that demonstrates that your source is still within its maximum TSM input level established during the previous... the calculation of TSM emission rate using Equation 10 of § 63.7530 that demonstrates that your source...

  20. 76 FR 67201 - Information Collection Activities: Oil and Gas Production Safety Systems; Submitted for Office of...

    Science.gov (United States)

    2011-10-31

    ... Production Safety Systems; Submitted for Office of Management and Budget (OMB) Review; Comment Request ACTION... the paperwork requirements in the regulations under Subpart H, ``Oil and Gas Production Safety Systems... H, Oil and Gas Production Safety Systems. Abstract: The Outer Continental Shelf (OCS) Lands Act, as...

  1. 76 FR 50748 - Information Collection Activity: Production Safety Systems, Revision of a Collection; Submitted...

    Science.gov (United States)

    2011-08-16

    ... in the regulations under ``Oil and Gas Production Safety Systems'' (OMB No. 1010-0059). DATES: Submit... 250, subpart H, Oil and Gas Production Safety Systems. OMB Control Number: 1010-0059. Abstract: The... public at large. Facility Production Safety System Applications are subject to cost recovery, and BOEMRE...

  2. 77 FR 11125 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2012-02-24

    ... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public...-known childhood conditions, such as Down syndrome, fetal alcohol syndrome, and neural tube defects, and... materials and prevention messaging about congenital CMV. The information collection activities will consist...

  3. 77 FR 16483 - Petition for Rulemaking Submitted by the Natural Resources Defense Council, Inc.

    Science.gov (United States)

    2012-03-21

    ...; ] NUCLEAR REGULATORY COMMISSION 10 CFR Part 50 Petition for Rulemaking Submitted by the Natural Resources... Natural Resources Defense Council, Inc. (NRDC or the petitioner), in the rulemaking process. The... establish station blackout (SBO) mitigation strategies and resources. The NRC determined that the issues...

  4. 13 CFR 108.2005 - Contents of plan submitted by SSBICs.

    Science.gov (United States)

    2010-01-01

    ... extent of the demand in such areas for Low-Income Investments and any factors or trends that may affect... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Contents of plan submitted by SSBICs. 108.2005 Section 108.2005 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW...

  5. Bond strength of resin-resin interfaces contaminated with saliva and submitted to different surface treatments

    DEFF Research Database (Denmark)

    Furuse, Adilson Yoshio; da Cunha, Leonardo Fernandes; Benetti, Ana Raquel

    2007-01-01

    of silane and adhesive system. Resin cylinders were placed over the treated surfaces. The specimens were stored in water or ethanol. Shear bond strength tests were performed and the mode of failure was evaluated. Data were submitted to two-way ANOVA and Dunnett T3 test. Contamination of resin...

  6. 41 CFR 301-52.6 - How do I submit a travel claim?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false How do I submit a travel claim? 301-52.6 Section 301-52.6 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES ARRANGING FOR TRAVEL SERVICES, PAYING TRAVEL EXPENSES, AND...

  7. 41 CFR 301-52.7 - When must I submit my travel claim?

    Science.gov (United States)

    2010-07-01

    ... travel claim? 301-52.7 Section 301-52.7 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES ARRANGING FOR TRAVEL SERVICES, PAYING TRAVEL EXPENSES, AND CLAIMING REIMBURSEMENT 52-CLAIMING REIMBURSEMENT § 301-52.7 When must I submit my travel...

  8. 78 FR 26775 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request...

    Science.gov (United States)

    2013-05-08

    ...; Distribution of Offsite Consequence Analysis Information Under the Clean Air Act (CAA) (Renewal) AGENCY... submitted an information collection request (ICR), Distribution of Offsite Consequence Analysis Information..., referencing Docket ID Number, EPA-HQ- OAR-2003-0073 to (1) EPA online using www.regulations.gov (our preferred...

  9. 78 FR 43878 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request; NESHAP...

    Science.gov (United States)

    2013-07-22

    ...: Submit your comments, referencing Docket ID Number EPA-HQ- OECA-2012-0687, to: (1) EPA online, using www... respondents to make ICR estimates consistent with the economic impact analysis, which contains the most recent information on existing and new sources. Based on the analysis, an average of 96 existing and 8.7 new sources...

  10. 76 FR 28788 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2011-05-18

    ... self-reported back and upper extremity pain among 960 employees performing delivery operations in 72... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public... a high level of acceptability to target employees and initial high effectiveness in reducing MSD...

  11. Low-level laser effects on bacterial cultures submitted to heat stress

    Science.gov (United States)

    Gonçalves, E. M.; Guimarães, O. R.; Geller, M.; Paoli, F.; Fonseca, A. S.

    2016-06-01

    Low-level lasers have been used worldwide to treat a number of diseases, pain relief, and wound healing. Some studies demonstrated that low-level laser radiations induce effects depending on the physiological state and DNA repair mechanisms of cells. In this work we evaluated the effects of low-level red and infrared lasers on Escherichia coli cells deficient in SOS responses submitted to heat stress. Exponential and stationary E. coli cultures of wild type (AB1157), RecA deficient (AB2463) and LexA deficient (AB2494), both SOS response deficient, were exposed to low-level red and infrared lasers at different fluences and submitted to heat stress (42 °C, 20 min). After that, cell survival and morphology were evaluated. Previous exposure to red, but not infrared lasers, increases survival fractions and decreases the area ratios of E. coli AB1157 cells submitted to heat stress. Our research suggests that a low-level red laser increases cell viability and protects cells from morphological alteration in E. coli cultures submitted to heat stress depending on laser wavelength and SOS response.

  12. Discussion of submitted posters for Section 2.3 (Rangeland Germplasm Resources)

    Science.gov (United States)

    As part of the IX International Rangeland Congress held in Rosario, Argentina, a total of 70 posters from 17 countries were submitted to Section 2.3 (Rangeland Germplasm Resources). These posters documented research conducted in five major regions of the world: South America, North America, Africa...

  13. 78 FR 64526 - Information Collection Activities: Sulphur Operations; Submitted for Office of Management and...

    Science.gov (United States)

    2013-10-29

    ...; 134E1700D2 EEEE500000 ET1SF0000.DAQ000] Information Collection Activities: Sulphur Operations; Submitted for Office of Management and Budget (OMB) Review; Comment Request ACTION: 30-day Notice. SUMMARY: To comply... regulations under Subpart P, Sulphur Operations. This notice also provides the public a second opportunity to...

  14. 78 FR 14763 - Notice of Public Information Collection Requirements Submitted to OMB for Review

    Science.gov (United States)

    2013-03-07

    ...; ] AGENCY FOR INTERNATIONAL DEVELOPMENT Notice of Public Information Collection Requirements Submitted to... information collection to OMB for review and clearance under the Paperwork Reduction Act of 1995, Public Law... International Development must collect information as part of the Public-Private Partnerships Opportunity...

  15. 77 FR 24210 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2012-04-23

    ... necessary control measures with respect to conveyances (e.g., airplanes, cruise ships, trucks, etc... HUMAN SERVICES Centers for Disease Control and Prevention Proposed Data Collections Submitted for Public... for Disease Control and Prevention (CDC) will publish periodic summaries of proposed projects. To...

  16. Dermatologic Lesions Submitted to an Oral and Maxillofacial Pathology Biopsy Service: An Analysis of 2487 Cases.

    Science.gov (United States)

    Reddy, Rekha; Davidova, Liya; Bhattacharyya, Indraneel; Cohen, Donald M; Islam, Mohammed N; Fitzpatrick, Sarah G

    2018-01-16

    Skin lesions are often submitted to oral and maxillofacial pathology practices. The purpose of this study is to evaluate the frequency, distribution, variability, and composition of dermatologic lesions within a large oral and maxillofacial pathology biopsy service. An IRB-approved retrospective search of skin lesions diagnosed at University of Florida oral and maxillofacial pathology biopsy service between 1994 and 2015 was performed. 2487 cases were included in the study. Gender was reported in 2466 cases, of which 59% were male and 41% female. Age was provided in 2367 cases and ranged from 2 weeks to 96 years with an average of 55 years. Location was indicated in 2473 cases. Lips were the most common (41.7%), followed by face (25.3%), neck (7.4%), nose (6.5%), periorbital (5.3%), ear (4.1%), and scalp (3.8%). Of the 2487 cases, five diagnoses (actinic keratosis/cheilitis, intradermal nevus, epidermal inclusion cyst, seborrheic keratosis, and basal cell carcinoma) constituted 84.4% of the cases. 69 of 2487 cases (2.8%) resulted in dermatopathologic consultation prior to final reporting. Skin lesions accounted for ~ 1.0% of all lesions submitted to an oral and maxillofacial pathology biopsy service. This study found a large variation in the dermatologic lesions submitted to an oral pathology biopsy service. Although most were routine in complexity, dermatopathology consultation was an important tool in the diagnosis of the more challenging cases. This study may help pathologists gain a better understanding of the frequency and variability of dermatologic lesions submitted to an oral and maxillofacial pathology biopsy service and promote more interdisciplinary consultation within the field. This study evaluated the incidence and scope of dermatologic lesions submitted to a large oral and maxillofacial pathology biopsy service over a long time period. A wide scope of lesions was found, and dermatopathology consultation was important to quality assurance.

  17. 25 CFR 900.9 - May the Secretary require an Indian tribe or tribal organization to submit any other information...

    Science.gov (United States)

    2010-04-01

    ... organization to submit any other information beyond that identified in § 900.8? 900.9 Section 900.9 Indians... Proposal Contents § 900.9 May the Secretary require an Indian tribe or tribal organization to submit any other information beyond that identified in § 900.8? No. ...

  18. 78 FR 17197 - Adequacy Status of Motor Vehicle Emissions Budgets in Submitted Ozone Maintenance Plan for San...

    Science.gov (United States)

    2013-03-20

    ... AGENCY Adequacy Status of Motor Vehicle Emissions Budgets in Submitted Ozone Maintenance Plan for San... Redesignation Request and Maintenance Plan'') are adequate for transportation conformity purposes. The San Diego Redesignation Request and Ozone Maintenance Plan was submitted to EPA on December 28, 2012 by the California Air...

  19. 13 CFR 126.616 - What requirements must a joint venture satisfy to submit an offer on a HUBZone contract?

    Science.gov (United States)

    2010-01-01

    ... must a joint venture satisfy to submit an offer on a HUBZone contract? A joint venture may submit an offer on a HUBZone contract if the joint venture meets all of the following requirements: (a) HUBZone joint venture. A qualified HUBZone SBC may enter into a joint venture with another qualified HUBZone SBC...

  20. 7 CFR 1412.34 - Submitting production evidence for establishing direct payment yields for oilseeds and pulse crops.

    Science.gov (United States)

    2010-01-01

    ... oilseeds and pulse crops. (a)(1) Reports of production evidence must be submitted when the owner elects to...-peril crop insurance loss adjustment settlement; or (vii) Other production evidence determined... 7 Agriculture 10 2010-01-01 2010-01-01 false Submitting production evidence for establishing...

  1. 23 CFR Appendix A to Part 1240 - Adjustment Procedures for State-Submitted Information (Calendar Years 1996 and 1997)

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Adjustment Procedures for State-Submitted Information (Calendar Years 1996 and 1997) A Appendix A to Part 1240 Highways NATIONAL HIGHWAY TRAFFIC SAFETY... 1240—Adjustment Procedures for State-Submitted Information (Calendar Years 1996 and 1997) A. In States...

  2. 19 CFR 149.6 - Entry and entry summary documentation and Importer Security Filing submitted via a single...

    Science.gov (United States)

    2010-04-01

    ... Security Filing submitted via a single electronic transmission. 149.6 Section 149.6 Customs Duties U.S... submitted via a single electronic transmission. If the Importer Security Filing is filed pursuant to § 149.2 of this part via the same electronic transmission as entry or entry/entry summary documentation...

  3. 41 CFR 102-118.500 - How does my agency handle a volunary refund submitted by a TSP?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How does my agency handle a volunary refund submitted by a TSP? 102-118.500 Section 102-118.500 Public Contracts and... Information for All Claims § 102-118.500 How does my agency handle a volunary refund submitted by a TSP? (a...

  4. 17 CFR 1.54 - Contract market rules submitted to and approved or not disapproved by the Secretary of Agriculture.

    Science.gov (United States)

    2010-04-01

    ... submitted to and approved or not disapproved by the Secretary of Agriculture. 1.54 Section 1.54 Commodity... Secretary of Agriculture. Notwithstanding any provision of these rules, any bylaw, rule, regulation, or resolution of a contract market that was submitted to the Secretary of Agriculture pursuant or § 1.38(a) or...

  5. 20 CFR 667.120 - What planning information must a State submit in order to receive a formula grant?

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What planning information must a State submit... INVESTMENT ACT Funding § 667.120 What planning information must a State submit in order to receive a formula grant? Each State seeking financial assistance under WIA sections 127 (youth) or 132 (adults and...

  6. Experience of families of children and adolescents submitted to Hematopoietic Stem Cell Transplantation

    Directory of Open Access Journals (Sweden)

    Verônica de Azevedo Mazza

    2016-12-01

    Full Text Available A descriptive study with a qualitative approach to describe how families of children and adolescents submitted to Hematopoietic Stem Cell Transplantation went through this experience. We conducted semi-structured interviews with 16 relatives of children and adolescents submitted to transplantation between December of 2014 to March of 2015 at the bone marrow transplantation service at a university hospital located at the South of Brazil. We analyzed the data with steps described by Creswell, with the support of the software IRAMUTEQ. From this analysis, the emerging categories were: the mother as an active subject in the transplantation process; family experience with the transplantation; transplantation impact for the child and/or adolescent; and, transplantation: from fear to hope. Considering our results, it is possible to ponderate about the care provided by the nursing team, becoming indispensable for these professionals to plan assistance focused not only on the patient but the whole family nucleus.

  7. Color and opacity of composites protected with surface sealants and submitted to artificial accelerated aging.

    Science.gov (United States)

    Aguilar, Fabiano Gamero; Roberti Garcia, Lucas da Fonseca; Cruvinel, Diogo Rodrigues; Sousa, Ana Beatriz Silva; de Carvalho Panzeri Pires-de-Souza, Fernanda

    2012-01-01

    To evaluate the color similarity, stability and opacity of composites (TPH, Charisma, and Concept, shade A2) protected with surface sealants (Fortify Plus and Biscover) and cyanoacrylate (Super Bonder). Forty specimens of each composite were made and separated into 4 groups (n=10) according to the surface protection: GI - without sealant; GII - cyanoacrylate; GIII - Fortify Plus; GIV - Biscover. Color and opacity readings were taken before and after Artificial Acelerated Aging (AAA) and the values obtained for color stability were submitted to statistical analysis by 2-way ANOVA and Bonferroni's test (Pcolor similarity were submitted to 1-way ANOVA and Tukey's test (Pcolor similarity among them. All composites presented color alteration after AAA with clinically unacceptable values. Protected groups presented lower opacity variation after AAA, in comparison with the control goup. SEM evaluation demonstrated that AAA increased the surface irregularities in all of the studied groups. Surface sealants were not effective in maintaining composite color, but were able to maintain opacity.

  8. Effect of postpolymerization method on the color stability of composite resins submitted to ultraviolet aging.

    Science.gov (United States)

    Santos, Paulo Henrique dos; Souza, Fernando Isquierdo de; Guedes, Ana Paula Albuquerque; Pavan, Sabrina

    2012-06-01

    The aim of this research was to evaluate the effect of postpolymerization method on the color stability of resin-based composites. Samples of direct and indirect restorative materials were polymerized with two photo-curing units (Visio photo-curing oven system and LED Elipar Freelight 2). All samples were submitted to an initial chromatic analysis using a spectrometer and submitted to ultraviolet-accelerated artificial aging. The direct material showed less color change than the indirect material, independent of the photo-activation method used. Samples photo cured with the LED system showed less change than those photo cured with the Visio system. The postpolymerization oven did not improve the color stability of direct and indirect resin-based composites.

  9. Experiments on heat pipes submitted to strong accelerations; Experimentation de caloducs soumis a de fortes accelerations

    Energy Technology Data Exchange (ETDEWEB)

    Labuthe, A. [Dassault Aviation, 92 - Saint Cloud (France)

    1996-12-31

    In order to evaluate the possibility to use heat pipes as efficient heat transfer devices in aircrafts, a study of their behaviour during strong accelerations is necessary. This study has been jointly carried out by the Laboratory of Thermal Studies of Poitiers (France) and Dassault Aviation company. It is based on a series of tests performed with an experimental apparatus that uses the centrifugal effect to simulate the acceleration fields submitted to the heat pipe. Un-priming - priming cycles have been performed under different power and acceleration levels and at various functioning temperatures in order to explore the behaviour of heat pipes: rate of un-priming and re-priming, functioning in blocked mode etc.. This preliminary study demonstrates the rapid re-priming of the tested heat pipes when submitted to favourable acceleration situations and the possibility to use them under thermosyphon conditions despite the brief unfavourable acceleration periods encountered. (J.S.)

  10. Performance of layers submitted to different forced-molting methods and different temperatures

    Directory of Open Access Journals (Sweden)

    S Sgavioli

    2011-09-01

    Full Text Available This study was carried out to evaluate the performance and egg quality of laying hens, in their second laying cycle submitted to different forced-molting methods and three environmental temperatures. Six hundred layers were distributed in a completely randomized experimental design with 15 treatments with five replicates of eight birds each, according to 5x3 factorial arrangement (molting methods vs. temperatures. The following forced-molting methods were applied: 90%, 70%, 50% dietary alfalfa inclusion, addition of 2,800 ppm zinc, and feed fasting. Temperatures were: 20 ºC, 27 ºC and 35 ºC. At the end of each period of the second laying cycle, bird performance and egg quality were evaluated. Data were submitted to analysis of variance and means were compared by orthogonal and polynomial contrasts. The highest alfalfa inclusion level (90% alfalfa and 10% basal diet proved to be efficient as compared to the other methods, independently of temperature.

  11. Think.Check.Submit.: the campaign helping researchers navigate the scholarly communication landscape

    Directory of Open Access Journals (Sweden)

    Helen Dobson

    2016-11-01

    Full Text Available As the number of new publishers and journals increases, so does the emergence of deceptive or ‘predatory’ publishers. Inexperienced researchers, particularly those in the developing world, are known to be vulnerable to spam e-mails inviting them to submit papers to journals with no discernible reputation. Think.Check.Submit. is a collective response to this problem from cross-industry stakeholders. The campaign provides clear and simple guidance to help researchers make informed choices about their publications. The resources can also be used by librarians responsible for developing researchers’ knowledge of the scholarly communication landscape or disseminated by industry groups working to support researchers in their publishing.

  12. BODY IMAGE, ANXIETY AND DEPRESSION IN WOMEN SUBMITTED TO BARIATRIC SURGERY

    OpenAIRE

    Almeida,Sebastião de Sousa

    2015-01-01

    The impact of overweight and bariatric surgery can lead to psychological complications, such as: anxiety and depression and Body Image disorders. This study evaluated symptoms of anxiety and depression and body image in women submitted to bariatric surgery. Fifty women responded to Beck anxiety inventory (BAI), Beck depression inventory (BDI) and the figure rating scale (FRS) before and four months after bariatric surgery. Anthropometric evaluation was performed to obtain the Body Mass Index ...

  13. Sodium bicarbonate as prevention of metabolic acidosis in sheep submitted to experimental ruminal acidosis

    OpenAIRE

    Laskoski, Luciane M.; Muraro, Lívia S.; Santana Júnior, Marinho S.; Carvalho, Mariana B.; Freitas, Silvio H.; Dória, Renata G.S.; Santos, Marcelo D.; Dittrich, Rosangela Locatelli

    2014-01-01

    The aim of this study was to evaluate the preventive effect of sodium bicarbonate on systemic acidosis due to ruminal acidosis, which was induced by ingestion of concentrate after prolonged fasting. Fourteen sheep were divided into three experimental groups: control group (Cg), with four sheep, submitted to fasting without development of ruminal acidosis; no-treated group (NTg), with five sheep with rumen acidosis without preventive treatment; and treated group (Tg), with five sheep with rume...

  14. Charring rate determination of wood pine profiles submitted to high temperatures

    OpenAIRE

    Fonseca, E.M.M.; Barreira, Luísa

    2009-01-01

    The wood material presents an increasing use for structural engineering applications in buildings and other specials engineering production. To assess safety rules, this type of elements should have sufficient mechanical resistance to guarantee the design loads. Wood is a natural material and is submitted to many constantly changing influences. The high wood vulnerability, due accidental conditions, requires rigorous thermal and mechanical assessment. The combustion and the ...

  15. Requirements for ethics committee review for studies submitted to Implementation Science

    Directory of Open Access Journals (Sweden)

    Mittman Brian

    2011-03-01

    Full Text Available Abstract The requirement for ethics review of studies submitted to Implementation Science has been unclear. Therefore, in this editorial, we set out our requirements for ethics committee review of experimental and non-experimental studies. For any study that meets the criteria of human subject research (which includes research on healthcare providers, irrespective of study design, we will require proof of either satisfactory ethics committee review or of the granting of an official exemption or waiver.

  16. Evaluation of blood glucose in type II diabetic patients submitted to local anesthesia with different vasoconstrictors

    OpenAIRE

    MELLO, Renan Pollettini de; Ramacciato, Juliana Cama; PERUZZO, Daiane Cristine; Vicentini,Carllini Barroso; Bergamaschi,Cristiane de Cássia; Motta,Rogério Heládio Lopes

    2016-01-01

    ABSTRACT Objective: In the dental clinic, the use of local anesthetics containing vasoconstrictors in diabetic patients are still controversial raising some doubts. Thus, the objective of this randomized crossover clinical trial was to evaluate blood glucose, pulse oximetry and heart rate of type 2 diabetic patients when submitted to local anesthesia using prilocaine 3% associated to felypressin 0,03UI / ml (G1) and 2% lidocaine associated to epinephrine 1: 100,000 (G2). Methods: The sample...

  17. Calcium and calcium magnesium carbonate specimens submitted as urinary tract stones.

    Science.gov (United States)

    Gault, M H; Chafe, L; Longerich, L; Mason, R A

    1993-02-01

    Of 8,129 specimens submitted as urinary stones from 6,095 patients, 67 from 15 patients were predominantly calcium carbonate or calcium magnesium carbonate (dolomite) by infrared analysis. Detailed study of 1 man and 4 women who submitted 3 or more such specimens showed that all were of aragonite calcium carbonate crystal form in 2 women and all calcite in the man. All 3 patients had a long history of nephrolithiasis preceding submission of calcium carbonate stones. There was frequent and often painful spontaneous passage of many small stones. Medullary sponge kidney was reported in 2 patients. Specimens submitted by the other 2 women included dolomite and quartz artifacts. Of the other 10 patients 4 had calcite and 1 had aragonite (possibly true stones). Five patients had artifacts with dolomite in 3 and mixed specimens in 2. True calcium carbonate kidney stones and calcium carbonate artifacts may be difficult to distinguish, and dolomite and quartz artifacts may require x-ray diffraction for clear-cut diagnosis.

  18. Spiders (Araneae) Found in Bananas and Other International Cargo Submitted to North American Arachnologists for Identification.

    Science.gov (United States)

    Vetter, Richard S; Crawford, Rodney L; Buckle, Donald J

    2014-11-01

    Spiders found in international cargo brought into North America are sometimes submitted to arachnologists for identification. Often, these spiders are presumed to be of medical importance because of size or a submitter's familiarity with a toxic spider genus from the continent of origin. Starting in 2006, requests were made for spiders found in international cargo brought into North America, in addition to the specimens from similar cargo shipments already in our museum collections. This was an ad hoc study that allowed us to focus on spiders of concern to the discoverer. We identified 135 spiders found in international cargo. A key for the most common species is provided. The most frequently submitted spiders were the pantropical huntsman spider, Heteropoda venatoria (L.) (Sparassidae), and the redfaced banana spider, Cupiennius chiapanensis Medina Soriano (Ctenidae). Spiders of medical importance were rare. The most common cargo from which spiders were submitted was bananas with most specimens coming from Central America, Ecuador, or Colombia. Lack of experience with nonnative fauna caused several experienced American arachnologists to misidentify harmless ctenid spiders (C. chiapanensis, spotlegged banana spider, Cupiennius getazi Simon) as highly toxic Phoneutria spiders. These misidentifications could have led to costly, unwarranted prophylactic eradication measures, unnecessary employee health education, heightened employee anxiety and spoilage when perishable goods are left unloaded due to safety concerns. © 2014 Entomological Society of America.

  19. Performance of children at risk for reading difficulties submitted to an intervention program.

    Science.gov (United States)

    Silva, Nathane Sanches Marques; Crenitte, Patrícia Abreu Pinheiro

    To assess the applicability of an intervention program to children at risk for reading disabilities. This experimental study compared 10 children at risk for reading difficulty submitted to a phonological decoding intervention program (study group) with 10 other children at risk for reading difficulty not submitted to the program (control group). The intervention program was based on two international studies. It comprised 24 sessions: the first 12 sessions were conducted with groups of two to three children, whereas the others were performed individually. The sessions lasted 50 minutes and were held twice a week. Statistical analysis was conducted using the Student's t-test and the Wilcoxon Signed-Rank test. Children at risk for reading difficulties submitted to the phonological decoding intervention program showed statistically significant improvement at post-assessment in the performance of the following skills: letter naming; phoneme-grapheme relationship; phonological awareness; phonological working memory for non-words; phonological working memory for digits in direct order; alphabet recognition in sequence; writing under dictation of words and pseudowords; reading of words and pseudowords. The phonological decoding intervention program showed applicability to improve the prerequisite skills of reading and writing of children at risk for reading disabilities.

  20. Obese patients with type 2 diabetes submitted to banded gastric bypass: greater incidence of dumping syndrome.

    Science.gov (United States)

    Padoin, Alexandre Vontobel; Galvão Neto, Manoel; Moretto, Myriam; Barancelli, Fabiano; Schroer, Caroline Eckerdt; Mottin, Cláudio Corá

    2009-11-01

    Dumping syndrome is one of ten most common complications in morbidly obese patients operated. Recent studies in relation to type 2 diabetes mellitus (DM2) in patients submitted to gastric bypass led us to examine the different outcomes in this group of patients. Our objective was to determine the difference in the prevalence of dumping syndrome in patients with DM2 submitted to gastric bypass. In this retrospective study, 49 diabetic and 54 non-diabetic morbidly obese patients were submitted to gastric bypass and followed up at 3, 6, and 12 months after surgery. The occurrence of dumping was determined by the patient's medical chart, where it was considered positive if recorded in at least one of three evaluations. The 103 patients evaluated had a mean BMI of 49.5 +/- 9.3 kg/m(2) and mean age of 38 +/- 9.7 years, with 75.7% being women. The prevalence of dumping syndrome in this population was 24.3%. The prevalence of dumping was greater in patients with DM2 (44.9%) when compared to the control group (5.6%; p dumping syndrome. Dumping syndrome is a common postoperative complication in gastric bypass. Patients with DM2 show a greater postoperative prevalence of dumping.

  1. News from the Library: Share your work, submit your thesis to CDS!

    CERN Multimedia

    CERN Library

    2011-01-01

    Are you a student paid by CERN, using CERN equipment or advised by CERN staff and you are currently writing a thesis? Then you should know that you are welcome to submit your final work to the CERN Document Server (CDS), where it will be made available by Open Access.   This is the most efficient way of sharing your work within the community - your thesis will certainly find a much greater audience than if you follow the advice of certain dubious publishing companies (see the article Free access to science... but at what cost? published in this issue). At the same time, you ensure long-term storage of your file. All theses qualify, from bachelor to PhD, and any language is accepted. You simply go to CDS and submit your work. If your thesis was written some years ago it is still not too late to submit it; it will then get a new life on CDS! More information here. CERN Theses collection here. If you have any questions or submission problems, please do not hesitate to contact Catherine Cart. ...

  2. Time influence of mechanical ventilation on functional independence in patients submitted to cardiac surgery: literature review

    Directory of Open Access Journals (Sweden)

    André Luiz Cordeiro

    Full Text Available Abstract Introduction: Patients submitted to cardiovascular surgery present motor and respiratory complications mainly due to high surgery manipulation and the use of mechanical ventilation. Reducing the weaning start time and disconnecting patient's ventilation system prematurely can decrease the pulmonary complications and hospitalization time. Motor complications are the most relevant as they have a direct effect on functional independence provoked by immobility time. Objectives : Identify if mechanical ventilation time has an impact on functional capacity on patients submitted to cardiac surgery in order to contribute to the establishment of reliable evidence to practice through this patient's profile. Materials and methods : Original articles were analyzed, published between 2000 and 2014, which focused on the influence of mechanical ventilation time concerning the functional independence on patients submitted to cardiac surgery, contained in the following electronic database: Scielo, BIREME (LILACS, PubMed e CAPES. Results : It was observed that the length of stay in the intensive care unit in cardiac surgery was influenced directly by CPB, VM and pulmonary dysfunction. Functional independence was compromised in patients with longer duration of mechanical ventilation, postoperative pain and prolonged bed rest. It was also found that there is no consensus on the protocol for improved functional capacity. Conclusion : There is a functional decline in patients undergoing cardiac surgery, especially those at increased length of stay in mechanical ventilation, reflecting a direct and negative impact on their functional independence and quality of life.

  3. Effect of racial crossing on the scrotum-testicular biometry in sheep submitted to scrotal insulation

    Directory of Open Access Journals (Sweden)

    Antônio F.S. Lisboa-Neto

    Full Text Available ABSTRACT: The objective of this study was to evaluate the effect of the racial crossing on scrotum-testicular biometric characteristics of four sheep Santa Ines and four crossbred (Santa Ines x Dorper submitted to scrotal insulation, following the return of these characteristics to values previously reported. For this, two measurements were made regarding the scrotal circumference (SC, length (L and testicular width (W before treatments. The testicular volume (V was calculated by the formula V=2 [(r2 x π x H]. The pouches were made with double-layer plastic, internally lined with cotton, and fixed around the spermatic funiculus and scrotum with adhesive tape and bandage remaining in this position for seven days. Measurements were made every seven days, totaling 15 measurements throughout the experiment. The data were submitted to analysis of variance (ANOVA to a randomized block design with two blocks, 15 treatments and four replications. The variables analyzed were subjected to Dunnett test at 5% probability, to compare the values obtained before and after insulation. For comparison between the breeds, the variables were submitted to Tukey test at 5% probability. All animals studied suffered significant influence (P<0.05 after scrotal insulation, but Santa Ines returned to the values previously observed in a shorter period than the crossbred. In summary, sheep Santa Ines have a higher resistance than crossbred animals when subjected to thermal stress induced by scrotal insulation.

  4. Authorship affiliations in original articles submitted to the International Journal of Tuberculosis and Lung Disease.

    Science.gov (United States)

    Plaisant, A; Pierard, C; Beyers, N; Chan-Yeung, M; Enarson, D A

    2010-12-01

    To ascertain whether the first (principal) and last (senior) authors of articles are affiliated to an organisation belonging to the study country in an analysis of high- and upper-middle-income countries, and low- and lower-middle-income countries. Prospective review of all original articles (n = 911) submitted to the International Journal of Tuberculosis and Lung Disease (IJTLD) from June 2006 to May 2008. In 81% of the submitted articles both the first and the last authors were affiliated to the country of the study. Slightly more articles from low (10%) than from lower-middle-income, high- and upper-middle-income countries (all 4%) had neither the first author nor the last author affiliated to the study country. For 17% of articles from low-income countries the senior author was not from the study country. Although acceptance of articles for publication in the IJTLD is not dependent on this criterion, we find that a substantial proportion of authors from low- and middle-income countries were listed as principal and senior authors in articles submitted.

  5. Tensile strength of glass fiber posts submitted to different surface treatments.

    Science.gov (United States)

    Faria, Maria Isabel A; Gomes, Érica Alves; Messias, Danielle Cristine; Silva Filho, João Manoel; Souza Filho, Celso Bernardo; Paulino, Silvana Maria

    2013-01-01

    The aim of this in vitro study was to evaluate the tensile strength of glass fiber posts submitted to different surface treatments. Forty-eight maxillary canines had their crowns sectioned and root canals endodontically treated. The roots were embedded in acrylic resin and distributed into 3 groups according to the surface treatment: Group I: the posts were treated with silane agent for 30 s and adhesive; Group II: the posts were cleaned with alcohol before treatment with silane agent and adhesive; Group III: the posts were submitted to conditioning with 37% phosphoric acid for 30 s before treatment with silane agent and adhesive. Each group was divided into 2 subgroups for adhesive polymerization or not before insertion into the canal: A - adhesive was not light cured and B - adhesive was light cured. All posts were cemented with Panavia F and the samples were subjected to tensile strength test in a universal testing machine at crosshead speed of 1 mm/min. Data were submitted to one-way ANOVA and Tukey's test at 5% significance level. There was statistically significant difference (p0.05). It was concluded that the products used for cleaning the posts influenced the retention regardless of adhesive light curing.

  6. Swimming does not alter nociception threshold in obese rats submitted to median nerve compression.

    Science.gov (United States)

    Coradini, Josinéia Gresele; Kunz, Regina Inês; Kakihata, Camila Mayumi Martin; Errero, Tatiane Kamada; Bonfleur, Maria Lúcia; Ribeiro, Lucinéia de Fátima Chasko; Brancalhão, Rose Meire Costa; Bertolini, Gladson Ricardo Flor

    2015-01-01

    We, herein, analyzed the effect of swimming on nociception threshold and peripheral nerve regeneration in lean and obese rats submitted to median nerve compression. To induce obesity, newborn male Wistar rats received injections of monosodium glutamate (MSG), whereas the control (CTL) group received saline. The animals were separated into 6 groups; control and obese (CTL and MSG), control and obese with lesion (CTL LES and MSG LES), and control and obese with lesion submitted to physical exercise (CTL LES PE and MSG LES PE). Median nerve compression reduced nociception threshold in CTL LES and MSG LES rats. Swimming effectively altered nociception only in CTL LES PE animals. Lean and obese animals displayed histological differences, when compared to sedentary animals, and exercise improved axon regeneration in both groups. The brain-derived neurotrophic factor and GAP 43 protein expression was greater in animals submitted to nervous compression without alteration by exercise. In conclusion, swimming, a conservative treatment for peripheral nerve lesions, was not able to improve the nociception threshold in obese rats.

  7. 40 CFR 35.4145 - How much time do my group or other interested groups have to submit a TAG application to EPA?

    Science.gov (United States)

    2010-07-01

    ... announcing that EPA has received an LOI. This second 30-day period begins on the day after the first 30-day period § 35.4115 describes ends. EPA will only accept applications from groups that submitted an LOI... submitted an LOI of the new deadline for submitting TAG applications. (c) EPA will not accept other...

  8. 30 CFR 285.611 - What information must I submit with my SAP to assist MMS in complying with NEPA and other...

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What information must I submit with my SAP to... Assessment Plan § 285.611 What information must I submit with my SAP to assist MMS in complying with NEPA and other relevant laws? (a) You must submit with your SAP detailed information to assist MMS in complying...

  9. Final Progress Report submitted via the DOE Energy Link (E-Link) in June 2009 [Collaborative Research: Decadal-to-Centennial Climate & Climate Change Studies with Enhanced Variable and Uniform Resolution GCMs Using Advanced Numerical Techniques

    Energy Technology Data Exchange (ETDEWEB)

    Fox-Rabinovitz, Michael S. [Univ. of Quebec (Canada); Cote, Jean [Univ. of Quebec (Canada)

    2009-10-09

    The joint U.S-Canadian project has been devoted to: (a) decadal climate studies using developed state-of-the-art GCMs (General Circulation Models) with enhanced variable and uniform resolution; (b) development and implementation of advanced numerical techniques; (c) research in parallel computing and associated numerical methods; (d) atmospheric chemistry experiments related to climate issues; (e) validation of regional climate modeling strategies for nested- and stretched-grid models. The variable-resolution stretched-grid (SG) GCMs produce accurate and cost-efficient regional climate simulations with mesoscale resolution. The advantage of the stretched grid approach is that it allows us to preserve the high quality of both global and regional circulations while providing consistent interactions between global and regional scales and phenomena. The major accomplishment for the project has been the successful international SGMIP-1 and SGMIP-2 (Stretched-Grid Model Intercomparison Project, phase-1 and phase-2) based on this research developments and activities. The SGMIP provides unique high-resolution regional and global multi-model ensembles beneficial for regional climate modeling and broader modeling community. The U.S SGMIP simulations have been produced using SciDAC ORNL supercomputers. The results of the successful SGMIP multi-model ensemble simulations of the U.S. climate are available at the SGMIP web site (http://essic.umd.edu/~foxrab/sgmip.html) and through the link to the WMO/WCRP/WGNE web site: http://collaboration.cmc.ec.gc.ca/science/wgne. Collaborations with other international participants M. Deque (Meteo-France) and J. McGregor (CSIRO, Australia) and their centers and groups have been beneficial for the strong joint effort, especially for the SGMIP activities. The WMO/WCRP/WGNE endorsed the SGMIP activities in 2004-2008. This project reflects a trend in the modeling and broader communities to move towards regional and sub-regional assessments and

  10. Delayed CTD data submitted by INIDEP ranging from 11/26/1984 - 10/16/1989 (NODC Accession 0039468)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD data were collected in the South Atlantic aboard the Oca Balda from 26 November 1984 to 16 October 1989. These data were submitted to NODC by the INSTITUTO...

  11. 78 FR 61349 - Information Collection Being Submitted for Review and Approval to the Office of Management and...

    Science.gov (United States)

    2013-10-03

    ...: [email protected] . To submit your PRA comments by email send them to: [email protected] mailto: [email protected] conflicts. Federal Communications Commission. Marlene H. Dortch, Secretary, Office of the Secretary, Office...

  12. 20 CFR 645.415 - What planning information must a State submit in order to receive a formula grant?

    Science.gov (United States)

    2010-04-01

    ... TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING WELFARE-TO-WORK GRANTS State Formula Grants Administration § 645.415 What planning information must a State submit in order to receive a...

  13. Extending eScience Provenance with User-Submitted Semantic Annotations

    Science.gov (United States)

    Michaelis, J.; Zednik, S.; West, P.; Fox, P. A.; McGuinness, D. L.

    2010-12-01

    eScience based systems generate provenance of their data products, related to such things as: data processing, data collection conditions, expert evaluation, and data product quality. Recent advances in web-based technology offer users the possibility of making annotations to both data products and steps in accompanying provenance traces, thereby expanding the utility of such provenance for others. These contributing users may have varying backgrounds, ranging from system experts to outside domain experts to citizen scientists. Furthermore, such users may wish to make varying types of annotations - ranging from documenting the purpose of a provenance step to raising concerns about the quality of data dependencies. Semantic Web technologies allow for such kinds of rich annotations to be made to provenance through the use of ontology vocabularies for (i) organizing provenance, and (ii) organizing user/annotation classifications. Furthermore, through Linked Data practices, Semantic linkages may be made from provenance steps to external data of interest. A desire for Semantically-annotated provenance has been motivated by data management issues in the Mauna Loa Solar Observatory’s (MLSO) Advanced Coronal Observing System (ACOS). In ACOS, photomoeter-based readings are taken of solar activity and subsequently processed into final data products consumable by end users. At intermediate stages of ACOS processing, factors such as evaluations by human experts and weather conditions are logged, which could impact data product quality. If such factors are linked via user-submitted annotations to provenance, it could be significantly beneficial for other users. Likewise, the background of a user could impact the credibility of their annotations. For example, an annotation made by a citizen scientist describing the purpose of a provenance step may not be as reliable as a similar annotation made by an ACOS project member. For this work, we have developed a software package that

  14. POSTOPERATIVE EFFECT OF PHYSICAL THERAPY RELATED TO FUNCTIONAL CAPACITY AND RESPIRATORY MUSCLE STRENGTH IN PATIENTS SUBMITTED TO BARIATRIC SURGERY

    OpenAIRE

    OLIVEIRA, Josélia Jucirema Jarschel de; FREITAS, Alexandre Coutinho Teixeira de; ALMEIDA, Andréa Adriana de

    2016-01-01

    ABSTRACT Background: Respiratory physiotherapy plays an important role preventing complications in bariatric surgery. Aim: To assess the effects of out-patient physiotherapy during post-operative period through respiratory pressures and functional capacity in individuals submitted to bariatric surgery. Method: A prospective longitudinal and controlled study was done in adults with body mass index (BMI) equal or greater than 40 kg/m², who have been submitted to bariatric surgery. They were ...

  15. What happens to medical articles submitted in Spanish that are not accepted for publication?

    Science.gov (United States)

    Matías-Guiu, J A; García-Ramos, R; Castellanos, M; Martínez-Vila, E; Matías-Guiu, J

    2013-05-01

    The fate of manuscripts submitted and subsequently rejected by Spanish-language journals is unknown. The present study was designed to determine whether or not articles submitted to Neurología are published following rejection, and if so, where. We searched Medline in late April 2012 and also analysed all manuscripts rejected by Neurología between October 2004 and April 2012 according to that journal's two databases. In that period, 1277 articles were submitted to the journal. Of the 271 manuscripts rejected by Neurología, 54 articles (19.9%) were published in other journals. Neurology journals published 31 of the manuscripts (57.4%); 43 manuscripts (79.6%) appeared in Spanish-language journals. Of the rejected manuscripts, 24.1% of the originals, 8.3% of the letters to the editor, 28.9% of the case reports, 22.6% of the reviews and 6.3% of the images were published. Authors with three previously published articles on the same topic managed to publish their manuscripts in 34% of the cases, compared to only 11.8% of authors with fewer published articles (P < .0001). Of the total manuscripts rejected between 2004 and 2010, 24.8% were eventually published. The median time lapse between article submission and publication was 13 months (range, 2-59 months). Manuscripts rejected by Neurología are often published in other journals, but this scenario is not as common as in English-language journals. In the case of Neurología, the editor's decision to reject an article is more significant than it would be in an English-language journal because the author will have fewer additional possibilities of having the manuscript published. Copyright © 2012 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

  16. Surgical risk index and surgical site infection in postpartum women submitted to cesarean section.

    Directory of Open Access Journals (Sweden)

    Luana Machado Chianca

    2015-01-01

    Full Text Available Backgound and Objectives: Considering the use of active surveillance assists in infection identification and the need for studies that use Surgical Risk Index (SRI for assessment of Surgical Site Infection (SSI in cesareans, this study aims to determine the incidence of SSI and analyze the applicability of SRI in the prediction of SSI in women in the postpartum period after being submitted to a cesarean section at a university hospital between April 2012 and March of 2013. Methods: Prospective cohort study. Information notifying SSI by active surveillance was collected daily from the medical records. After hospital discharge, the mothers were contacted through telephone calls to identify infection criteria within 30 days after the cesarean. Descriptive and comparative analyses were performed. The chi-square test was used to compare groups. Results: 737 cesareans were performed. Telephone contact was achieved with 507 (68.8% women up to 30 days postpartum, with loss of follow-up of 230 cases (31.2%. The medical consultation in the post-partum period occurred with 188 (37.08% women, with whom telephone contact was obtained, on average, 17.28 days (SD=8.39 after delivery. It was verified that 21 patients met the criteria for SSI, with a 4.14% rate. A total of 12 cases (57.1% were classified as superficial SSI, 5 (23.8% as deep and 4 (19.1% as infection of organs and cavities. The SRI and its risk variables were not associated with SSI in patients submitted to cesarean sections. Conclusion: The SRI and the risk variables included in this index were not associated to SSI in patients submitted to cesarean sections. KEYWORDS: Cesarean Section; Surgical Wound Infection; Epidemiological Surveillance; Infection Control; Risk Index; Disease Notification.

  17. Lipid profiles of follicular fluid from cows submitted to ovarian superstimulation.

    Science.gov (United States)

    Santos, P H; Fontes, P K; Franchi, F F; Nogueira, M F G; Belaz, K R A; Tata, A; Eberlin, M N; Sudano, M J; Barros, C M; Castilho, A C S

    2017-05-01

    Ovarian superstimulation with exogenous gonadotropins has been extensively used to produce in vivo-derived embryos for embryo transfer in cattle. This process modifies the antral follicle microenvironment and affects oocyte and embryo quality as well the differentiation of granulosa cells. Lipids play significant roles in the cell, such as energy storage, cell structure, and fine-tuning of the physical properties and functions of biological membranes. The phospholipid (PL) contents as well as the effects of superstimulatory treatments on the PL profile of follicular fluid from cows, however, remain unknown. Therefore, to gain insight into the effects of superstimulation with follicle-stimulating hormone (FSH; P-36 protocol) or FSH combined with equine chorionic gonadotropin (eCG; P-36/eCG protocol) on the profile and abundance of PL from cows submitted or not submitted to superstimulatory protocols, were treated with these two superstimulatory protocols. As a control, non-superstimulated cows were only submitted to estrous synchronization. The follicular fluid was aspirated, the remaining cells removed and the follicular fluid stored at -80 °C until extraction. The lipid screening was performed by matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) and this technique allowed the identification of sphingomyelins (SM) and phosphatidylcholines (PC) and phosphoethanolamines (PE). The relative abundance of the ions observed in the three experimental groups was analyzed by multivariate and univariate statistical models. The phospholipid SM (16:0) and PC (36:4) and/or PC (34:1) were less (P cows compared to the control. In summary, ovarian superstimulation seems to modulate the PL content of bovine follicular fluid with a significant increase in PC (34:2), which jointly with others PC and SM, seems to offer a suitable biomarker involved with reproductive processes successful as ovary superstimulation response and embryo development. Copyright

  18. Microhardness and Roughness of Infiltrated White Spot Lesions Submitted to Different Challenges.

    Science.gov (United States)

    Neres, É Y; Moda, M D; Chiba, E K; Briso, Alf; Pessan, J P; Fagundes, T C

    A white spot lesion is the first clinical sign of a caries lesion and represents mineral loss from the enamel subsurface. The purpose of this study was to evaluate the microhardness and surface roughness of white spot lesions after application of a resin infiltrant and subjection to different challenges. Caries-like lesions were induced in bovine enamel discs (n=50), and the specimens were randomly divided into five study groups (n=10): demineralized enamel (negative control, G1), infiltrated enamel (G2), infiltrated enamel submitted to brushing (G3), infiltrated enamel submitted to pH cycling (G4), and infiltrated enamel submitted to artificial aging (G5). Half of each enamel surface was used as its own positive control. Roughness data were analyzed using the Kruskal-Wallis test followed by the Dunn test. Results from microhardness were analyzed by two-way analysis of variance, followed by the Tukey test for multiple comparisons. The level of significance was set at 5%. Microhardness and roughness values obtained from the test side of the specimens were significantly lower compared with the sound enamel for all groups. Microhardness values obtained for G2, G3, and G5 were not significantly different. Values found for G1 were significantly lower compared with those for G2, G3, and G5. The lowest microhardness values were observed for G4, which was significantly different from the other groups. Surface roughness was not significantly different between G2 and G3. The resin infiltrant presented superiority over the unprotected white spot lesions, as they were more resistant to mechanical and aging challenges. However, resin infiltration was not able to reestablish the properties of sound enamel and was not resistant to a new cariogenic challenge.

  19. On the low vibration modes observed in a sphere submitted to a tangential contact force.

    Science.gov (United States)

    De Billy, M

    2006-12-01

    In this paper we discuss the existence of translational and rotational displacements of a sphere submitted to a tangential contact force. On the basis of the Bogdanov and Skvortsov's works [A.N. Bogdanov, A.T. Skvortsov, Sov. Phys. Acoust. 38 (1992) 224-226.] the dispersion equation has been established and solved for any value of the frequency in the case of the linear approximation. The present experimental analysis confirms that it exists two branches: an upper branch associated to the translation of the sphere and a lower branch characteristic of the rotation of the bead.

  20. Socio-demographic, clinical and laboratory profile of patients submitted to hemodialysis

    OpenAIRE

    Cristina Trevizan Telles; Taise Dobner; Gabriela Pomatti; Felipe Brock; Luiz Antonio Bettinelli

    2014-01-01

    The aim of the study was to characterize the patients with Chronic Kidney Disease submitted to hemodialysis in Rio Grande do Sul, Brazil, regarding the socio-demographic, clinical and laboratory characteristics. It is a cross-sectional study with 90 hemodialysis patients made in July and August 2013, through interviews. The results showed that 77.8% of the patients were male, with average age of 53.52 years and 66.7% were married. The average of schooling was 6.61 years; the Unified Health Sy...

  1. How to Select a Journal to Submit and Publish Your Biomedical Paper?

    Directory of Open Access Journals (Sweden)

    Farhad Shokraneh

    2012-03-01

    Full Text Available Introduction: selection of journal for publication purpose is one of concerns of biomedical researchers. They apply various criteria to choose appropriate journal. Here, we have tried to collect main criteria biomedical researchers use to select a journal to submit their work. Methods: we collected these criteria through focus group conversations with researchers during our careers, feedbacks from participants of our scientific writing workshops and non-systematic reviewing of some related literature. Results: we have presented a summative and informative guidance in selection of biomedical journals for biomedical paper submission and publication. Conclusion: Categorized criteria as a mnemonic tool for authors may help the authors in journal selection process.

  2. Neocortical and olfactory bulb activity, in armadillos submitted to covering with soil.

    Science.gov (United States)

    Affanni, J M; Casanave, E B; García Samartino, L; Ferrari, R

    1986-11-01

    Armadillos were submitted to an experimental condition in which their head and thorax were covered by a layer of soil 30 cm high. In this condition the electrical activity of the neocortex and of the olfactory bulbs was studied. Neocortical activity did not show signs of damage remaining without gross changes before, during and after the covering with soil. The olfactory bulbs showed a great decrease of bursting sinusoidal activity which almost instantaneously reversed when the soil was removed. The mechanisms of these changes are discussed.

  3. Incidence of Dientamoeba fragilis in faecal samples submitted for routine microbiological analysis.

    Science.gov (United States)

    Windsor, J J; Rafay, A M; Shenoy, A K; Johnson, E H

    1998-09-01

    Over a six-month period, 857 faecal samples were submitted to the Department of Microbiology and Immunology at Sultan Qaboos University Hospital in Oman, for routine microbiological examination. All samples were stained using the Gomori trichrome method. Trophozoites of Dientamoeba fragilis were detected in 41 (5.1%) patients, making it the most common enteropathogen found in the study. Of the patients with pure D. fragilis infection, 83% had abdominal pain, the duration of which varied from one month to two years. The use of permanently stained smears allowed detection of D. fragilis for the first time in the Sultanate of Oman.

  4. Oxidative stress in carotid arteries of patients submitted to carotid endarterectomy. The role of aging process.

    Science.gov (United States)

    Lucas, Márcio Luís; Carraro, Cristina Campos; Belló-Klein, Adriane; Kalil, Antônio Nocchi; Aerts, Newton

    2016-08-01

    To evaluated the role of oxidative stress on aging process in patients submitted to carotid endarterectomy. Twenty patients were divided into two groups: older group (≥ 70 years old); and the younger group (aging is associated with increased concentrations of oxygen species and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity as so as nitrite reduction in human carotid artery specimens. Maybe therapies that block NADPH oxidase activity and enhance nitrite stores would be a good strategy to reduce the effect of oxidative stress in arterial aging.

  5. Plagiarism in submitted manuscripts: incidence, characteristics and optimization of screening-case study in a major specialty medical journal.

    Science.gov (United States)

    Higgins, Janet R; Lin, Feng-Chang; Evans, James P

    2016-01-01

    Plagiarism is common and threatens the integrity of the scientific literature. However, its detection is time consuming and difficult, presenting challenges to editors and publishers who are entrusted with ensuring the integrity of published literature. In this study, the extent of plagiarism in manuscripts submitted to a major specialty medical journal was documented. We manually curated submitted manuscripts and deemed an article contained plagiarism if one sentence had 80 % of the words copied from another published paper. Commercial plagiarism detection software was utilized and its use was optimized. In 400 consecutively submitted manuscripts, 17 % of submissions contained unacceptable levels of plagiarized material with 82 % of plagiarized manuscripts submitted from countries where English was not an official language. Using the most commonly employed commercial plagiarism detection software, sensitivity and specificity were studied with regard to the generated plagiarism score. The cutoff score maximizing both sensitivity and specificity was 15 % (sensitivity 84.8 % and specificity 80.5 %). Plagiarism was a common occurrence among manuscripts submitted for publication to a major American specialty medical journal and most manuscripts with plagiarized material were submitted from countries in which English was not an official language. The use of commercial plagiarism detection software can be optimized by selecting a cutoff score that reflects desired sensitivity and specificity.

  6. [Analysis of the dumping syndrome on morbid obese patients submitted to Roux en Y gastric bypass].

    Science.gov (United States)

    Loss, Angelo Bustani; de Souza, Antônio Augusto Peixoto; Pitombo, Cid Araújo; Milcent, Marcel; Madureira, Fernando Athaíde Veloso

    2009-10-01

    The objective of this research was to determine the real prevalence and characteristics of dumping syndrome in a series of cases submitted to laparoscopic Roux-en-Y gastric bypass for morbid obesity. We assessed dumping symptoms in 34 patients who had undergone that procedure; they filled a questionnaire, which included the dumping clinical diagnosis score proposed by Sigstad. regarding patients' complaints, dumping prevalence was 44%. This number increased to 76% when applying the Sigstad's score. The most frequent symptoms were 'need for lying down' (88%), fatigue (69%) and sleepiness (69%). Only 28% of the dumpers felt incapable of performing everyday activities. There was no difference in weight loss percentage between dumpers and non-dumpers. The Sigstad score is an usefull tool for the diagnostic of dumping, but a critic vision must be adopted when using in patients submitted to the Roux en Y gastric bypass. The dumping syndrome was frequent in this group, although usually under-diagnosed; it neither hampers patients' everyday activities considerably, nor helps in the weight-loosing process.

  7. Establishment of peritoneal liquid electrophoretogram from healthy horses and horses submitted to experimentally induced intestinal obstruction

    Directory of Open Access Journals (Sweden)

    A.F.S. Nogueira

    2014-06-01

    Full Text Available The initial inflammatory stages of the colic syndrome include changes known as acute phase response. The aim of this study was to contribute with the establishment of reference values concerning the electrophoretogram of peritoneal liquid from healthy horses and horses submitted to experimentally induced intestinal obstruction. Twenty-one horses were allotted in four groups: duodenal obstruction (DG, ileum obstruction (IG, left-dorsal colon obstruction (MG, and control group (CG. Peritoneal liquid was sampled before obtruction (T0, with 3 hours of obstruction (T3 and 6, 30, 102 and 174 hours after desobstructing (T6, T30, T102 and T174, respectively. Total protein levels were determined by the biuret method and protein fractions were obtained by SDS-PAGE electrophoresis. The acute phase proteins (APP identified were Immunoglobulin-A, ceruloplasmin, transferrin, albumin, α1-antitrypsin, heavy and light chains of immunoglobulin-G, haptoglobin, α1-acid glycoprotein and a still unnamed protein, which was called P24. There was no difference (P>0.3 in protein levels among groups, although a significant difference (P>0.05 was observed between distinct experimental moments in each group evidencing a higher response of the APP in the obstructed groups. The APP fractioning of the peritoneal liquid was standardized to establish a standard curve for healthy equines and those submitted to induced intestinal obstruction. Moreover, it was verified that the SDS-PAGE electrophoresis was sensitive and effective to help diagnose abdominal inflammatory processes.

  8. Effect of cement types on the tensile strength of metallic crowns submitted to thermocycling

    Directory of Open Access Journals (Sweden)

    Consani Simonides

    2003-01-01

    Full Text Available The relationship between metallic cast crowns and tensile strength according to cement types submitted to thermocycling was studied. Seventy-two metallic crowns were cast with Verabond II Ni-Cr alloy and cemented in standardized preparations with 10º tapering. Three types of finishing line (45-degree chamfered, 20-degree bevel shoulder and right shoulder were made with diamond burs on bovine teeth. Twenty-four metallic crowns in each group were randomly subdivided into three subgroups of 8 samples each according to the cement used: SS White zinc phosphate cement, Vitremer resin-modified glass ionomer cement, and Rely X resin cement and were submitted to thermocycling. Retention was evaluated according to tensile load required to displace the metallic cast crowns from tooth preparations with an Instron testing machine. ANOVA and Tukey's test showed a statistically significant difference among luting materials, with greater results for Rely X resin cement (24.9 kgf followed by SS White zinc phosphate cement (13.3 kgf and Vitremer resin-modified glass ionomer cement (10.1 kgf. The finishing line types did not influence the tensile resistance of the crowns fixed with the three cements. Increased tensile resistance of metallic crowns fixed on bovine teeth was obtained with resin cement, independent of the finishing line types.

  9. Color stability of maxillofacial silicone with nanoparticle pigment and opacifier submitted to disinfection and artificial aging

    Science.gov (United States)

    Filié Haddad, Marcela; Coelho Goiato, Marcelo; Micheline Dos Santos, Daniela; Moreno, Amália; Filipe D'Almeida, Nuno; Alves Pesqueira, Aldiéris

    2011-09-01

    The purpose of this study was to evaluate the color stability of a maxillofacial elastomer with the addition of a nanoparticle pigment and/or an opacifier submitted to chemical disinfection and artificial aging. Specimens were divided into four groups (n = 30): group I: silicone without pigment or opacifier, group II: ceramic powder pigment, group III: Barium sulfate (BaSO4) opacifier, and group IV: ceramic powder and BaSO4 opacifier. Specimens of each group (n = 10) were disinfected with effervescent tablets, neutral soap, or 4% chlorhexidine gluconate. Disinfection was done three times a week during two months. Afterward, specimens were submitted to different periods of artificial aging. Color evaluation was initially done, after 60 days (disinfection period) and after 252, 504, and 1008 h of artificial aging with aid of a reflection spectrophotometer. Data were analyzed by three-way ANOVA and Tukey test (α = 0.05). The isolated factor disinfection did not statistically influence the values of color stability among groups. The association between pigment and BaSO4 opacifier (GIV) was more stable in relationship to color change (▵E). All values of ▵E obtained, independent of the disinfectant and the period of artificial aging, were considered acceptable in agreement with the norms presented in literature.

  10. Color and opacity of composites protected with surface sealants and submitted to artificial accelerated aging

    Science.gov (United States)

    Aguilar, Fabiano Gamero; Roberti Garcia, Lucas da Fonseca; Cruvinel, Diogo Rodrigues; Sousa, Ana Beatriz Silva; de Carvalho Panzeri Pires-de-Souza, Fernanda

    2012-01-01

    Objectives: To evaluate the color similarity, stability and opacity of composites (TPH, Charisma, and Concept, shade A2) protected with surface sealants (Fortify Plus and Biscover) and cyanoacrylate (Super Bonder). Methods: Forty specimens of each composite were made and separated into 4 groups (n=10) according to the surface protection: GI - without sealant; GII - cyanoacrylate; GIII - Fortify Plus; GIV - Biscover. Color and opacity readings were taken before and after Artificial Acelerated Aging (AAA) and the values obtained for color stability were submitted to statistical analysis by 2-way ANOVA and Bonferroni’s test (P<.05). The values acquired for color similarity were submitted to 1-way ANOVA and Tukey’s test (P<.05). The specimen sufaces were compared before and after AAA using Scanning Electronic Microscopy (SEM). Results: Studied composites did not present the same values for the coordinates L*, a* and b * before AAA, indicating that there was no color similarity among them. All composites presented color alteration after AAA with clinically unacceptable values. Protected groups presented lower opacity variation after AAA, in comparison with the control goup. SEM evaluation demonstrated that AAA increased the surface irregularities in all of the studied groups. Conclusion: Surface sealants were not effective in maintaining composite color, but were able to maintain opacity. PMID:22229004

  11. Quality of life of women submitted to myocardial revascularization surgery in a public hospital

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    Rafaela Melo de Oliveira

    2010-09-01

    Full Text Available Objective: To analyze the sociodemografic profile, risck factors and the quality of life of women submitted to myocardial revascularization surgery. Methods: We conducted a qualitative study by applying a questionnaire on lifestyle and risk factors and an interview with four guiding questions to 15 revascularized inpatients of cardiology units of a referral public hospital and who had no manifestations of depression prior to surgery. Results: The patients profile showed that 9 (60% were Caucasian, 8 (54% had incomplete primary education, 4(27% were housewives, 9 (60% lived in urban area, 10 (67% were married, all had a family income lower than three minimum wages and 4(27% had only two kids. From the content analysis of the interviews, the following categories aroused: religiosity, disruption with everyday life, family and quality of life. Conclusion: We found out that the knowledge about the psychosocial structure of each patient helps in the treatment of the individual submitted to myocardial revascularization. By identifying the lifestyle and risk factors, women promote self-knowledge, which can avoid habits that lead to cardiovascular diseases. We suggest the development of strategies for prevention and health promotion involving the patients and their families so that there is an extension of hospital care at home and a betteradaptation to the new condition.

  12. Bond strength of resin-resin interfaces contaminated with saliva and submitted to different surface treatments

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    Adilson Yoshio Furuse

    2007-12-01

    Full Text Available The purpose of this study was to investigate the effect of different surface treatments on shear bond strength of saliva-contaminated resin-resin interfaces. Flat resin surfaces were fabricated. In the control group, no contamination or surface treatment was performed. The resin surfaces of the experimental groups were contaminated with saliva and air-dried, and then submitted to: (G1 rinsing with water and drying; (G2 application of an adhesive system; (G3 rinsing and drying, abrasion with finishing disks, etching and application of adhesive system; (G4 rinsing and drying, etching, application of silane and adhesive system. Resin cylinders were placed over the treated surfaces. The specimens were stored in water or ethanol. Shear bond strength tests were performed and the mode of failure was evaluated. Data were submitted to two-way ANOVA and Dunnett T3 test. Contamination of resin-resin interfaces with saliva significantly reduced shear strength, especially after prolonged storage (p<0.05. Similar values to the original bond strength were obtained after abrasion and application of adhesive (G3 or etching and application of silane and adhesive (G4. If contamination occurs, a surface treatment is required to guarantee an adequate interaction between the resin increments.

  13. A morphometric study of the intestinal mucosa of rats submitted to omentoenteropexy

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    Pedro Muñoz Fernandez

    2011-12-01

    Full Text Available CONTEXT: The omentoenteropexy technique was developed as an alternative method for intestinal neovascularization, due to the angiogenic properties of factors from the omentum. OBJECTIVES: This study investigated changes in intestinal villi heights and crypts depths due to surgical techniques: seromiotomy with and without omentoenteropexy. METHOD: Thirty rats were operated on, after being divided into three groups, namely GI, GII and GIII with 10 rats each. In the GI rats were submitted to omentoenteropexy; rats in GII were submitted only to a seromiotomy, and in the GIII only laparotomy. Sixty days after the first surgery, the animals were sacrificed and a segment of intestine was removed for histology using Masson's trichrome technique and morphometric study of intestinal mucosa. RESULTS: The histological findings showed that seromiotomy with or without omentoenteropexy increased the length of intestinal villi when compared with GIII (only laparotomy (analysis of variance: P = 0.0068; GI 38.88 ± 4.17; GII 39.41± 6.33; GIII 31.85 ± 5.56; GI = GII P>0.05; GII>GIII PGIII P<0.001. CONCLUSION: No differences were demonstrated in relation to crypt depths between the groups (P = 0.60. Ongoing studies are being set forth by our group to add more data on the role of omentopexy as a tool to promote neovascularization and intestinal mucosal growth.

  14. Effect of ionizing radiation on the taste function of patients submitted to head and neck radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Amaro Ilidio Vespasiano [Universidade Estadual de Campinas (UNICAMP), SP (Brazil); Galante, Celio [Santa Casa de Misericordia de Belo Horizonte, MG (Brazil). Div. de Radioterapia; Manzi, Flavio Ricardo, E-mail: manzi@pucminas.b [Pontificia Universidade Catolica de Minas Gerais (PUC-MG), Belo Horizonte, MG (Brazil)

    2011-09-15

    Objective: to evaluate the effects of ionizing radiation on the taste function in patients submitted to radiotherapy in the head and neck region. Materials and methods: twenty patients diagnosed with head and neck tumors and undergoing treatment in the Division of Radiotherapy at Santa Casa de Misericordia de Belo Horizonte, MG, Brazil, were selected. For their taste function testing, four solutions were manipulated with salt (NaCl), sugar (sucrose), citric acid (for acidity), and urea (for bitterness), at three different (low, medium and high) concentrations. Weekly tests were performed during the first three weeks of radiotherapy, with random administration of the solutions (three drops each) respecting the order of their concentration levels (low, medium and high). After the application of each solution, the patient reported which flavor he/she tasted. Results: a statistically significant difference was observed in the loss of taste function as the results in the 1st and 4th weeks of treatment were compared, with salty solution at the three concentration levels, with the sweet solution at low and medium concentrations, and with the sour and bitter solutions, only at low concentration. Conclusion: ionizing radiation alters the taste function of patients submitted to head and neck radiotherapy. (author)

  15. Content Analysis of Papers Submitted to Communications in Information Literacy, 2007-2013

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    Christopher V. Hollister

    2014-07-01

    Full Text Available The author conducted a content analysis of papers submitted to the journal, Communications in Information Literacy, from the years 2007-2013. The purpose was to investigate and report on the overall quality characteristics of a statistically significant sample of papers submitted to a single-topic, open access, library and information science (LIS journal. Characteristics of manuscript submissions, authorship, reviewer evaluations, and editorial decisions were illuminated to provide context; particular emphasis was given to the analysis of major criticisms found in reviewer evaluations of rejected papers. Overall results were compared to previously published research. The findings suggest a trend in favor of collaborative authorship, and a possible trend toward a more practice-based literature. The findings also suggest a possible deterioration in some of the skills that are required of LIS authors relative to the preparation of scholarly papers. The author discusses potential implications for authors and the disciplinary literature, recommends directions for future research, and where possible, provides recommendations for the benefit of the greater community of LIS scholars.

  16. Evaluation of anatomical and functional changes esophageal stump of patients with advanced megaesophagus submitted to subtotal laparoscopic esophagectomy Avaliação das alterações anatômicas e funcionais do coto esofágico de pacientes portadores de megaesôfago avançado submetidos à esofagectomia subtotal laparoscópica

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    Júverson Alves Terra Júnior

    2012-09-01

    Full Text Available PURPOSE: Evaluate anatomical and functional changes of the esophageal stump and gastric fundus of patients with advanced megaesophagus, submitted to laparoscopic subtotal esophagectomy. METHODS: Twenty patients with advanced megaesophagus, previously submitted to a videolaparoscopic subtotal esophagectomy , were evaluated. Were conducted: radiological evaluation of the stump esophagus with transposed stomach, electromanometric, endoscopic examination and histopathology of the esophageal stump and gastric fundus, without making gastric tube or pyloroplasty. RESULTS: It was observed that the average height and pressure of the anastomosis, in the electromanometric evaluation, were 23.45cm (±1.84cm and 7.55mmHg (±5.65mmHg. In patients with megaesophagus III, the pressure of the anastomosis was 10.91mmHg (±6.33mmHg, and pressure from the UES, 31.89mmHg (±14.64mm Hg, were significantly higher than those in grade IV. The pathological evaluation detected mild esophagitis in 35% of patients, moderate in 20% and acanthosis glicogenica in 45%. The examination of the gastric fundus showed that 50% of patients were infected with Helicobacter pylori. Chronic gastritis occurred in 95% of the patients. CONCLUSIONS: The laparoscopic esophagectomy shown to be effective in the treatment of advanced achalasia. The cervical level anastomosis protects the esophageal stump from the aggression resulted from gastric reflux after the esophagectomy.OBJETIVO: Avaliar as alterações anatômicas e funcionais do coto esofágico e fundo gástrico de pacientes com megaesôfago avançado, submetidos à esofagectomia subtotal laparoscópica. MÉTODOS: Vinte pacientes com megaesôfago avançado, previamente submetidos à esofagectomia subtotal videolaparoscópica, foram avaliados. Foram realizados: avaliação radiológica do coto esofágico com o estômago transposto, eletromanometria endoscopia e exame histopatológico do coto esofágico e fundo gástrico,sem fazer tubo g

  17. Young modulus variation of a brickwork masonry element submitted to high temperatures

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    Maciá, M. E.

    2013-03-01

    Full Text Available In order to understand the thermal behavior of the masonry elements submitted to high temperatures we need to know the variation of their thermal properties with regard to the temperature. Submitted to high temperatures clay brick masonry presents thermomechanical effects (as the variation of Young's modulus, the thermal expansion of the unit and the mortar, spalling, losses of resistance … as well as variation of the properties of the material as result of its degradation. In this article the variation of the module of elasticity of the unit and the mortar is described with regard to high temperatures according to the state of the knowledge. In this article is also exposed the results obtained from the experimental program carried out on elements of clay brick masonry submitted to high temperatures in order to observe the variation of Young's module related to temperature.

    La definición del comportamiento térmico de los elementos de fábrica sometidos a la acción del fuego requiere del conocimiento de la variación de sus propiedades termomecánicas con respecto a la temperatura. Ante las altas temperaturas la fábrica cerámica presenta efectos termomecánicos, como la variación del módulo de Young entre otros, así como la variación de las propiedades del material debidas a la degradación del mismo. En este artículo se describe la variación del módulo de elasticidad de la pieza y el mortero con respecto a altas temperaturas según el estado del conocimiento y se exponen los resultados obtenidos del programa experimental llevado a cabo sobre elementos de fábrica sometidos a altas temperaturas con el fin de observar la variación del módulo de Young con respecto a la temperatura.

  18. Resistance Mechanisms of Peltophorum dubium (Sprengel Taubert Submitted to Flood Conditions

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    Lara Siqueira Oliveira Carvalho

    Full Text Available ABSTRACT Peltophorum dubium (Sprengel Taubert seedlings were submitted to 60 days of flooding, with and without Ca+. During this period, growth, root anatomy and chlorophyll content were analyzed. The relative growth rates (RGR of roots and shoots were higher in non-flooded plants. The flooded treatments, with and without Ca+, have affected the roots growth but did not affect the shoot and the stem diameter. The anatomy analysis showed thickening of the sclerenchyma in 15 and 60 days in the flooded treatments with and without Ca+, and the vessel diameter was smaller at 45 days. The chlorophyll content differed, however it was not statistically significant. The results indicate that Peltophorum dubium as candidate specie for reforestation in areas subjected to continuous flooding for up to 60 days, since no mortality was observed.

  19. Listeria monocytogenes biofilm production on food packaging materials submitted to physical treatment

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    Patrizia Centorame

    2017-10-01

    Full Text Available Listeria monocytogenes (L.m. is an agent of serious foodborne illness. It is a major concern for the food industry, since microorganism, growing in biofilms is protected against cleaning and disinfection and is difficult to eradicate. Aim of this study was to develop a protocol to assess the ability of two flexible packaging materials, named HGP40 and GND35, submitted to corona discharge treatment, to limit the production of L.m. biofilm at 12±1°C. Two strains were selected for this study: L.m ATCC 7644 and L. m. EURL 12MOB098LM isolated from dairy products. Results suggest that both L.m. strains were able to form biofilm on packaging materials tested. The differences on HGP40 and GND35s treated and not treated surfaces were not statistically significant.

  20. Does a previous surgical experience interfere on psychic stress in patients submitted to major surgery?

    Science.gov (United States)

    Alberti, Luiz Ronaldo; Daian, Márcia Rodrigues; Petroianu, Andy

    2014-01-01

    to evaluate the impact of stress in patients undergoing major surgeries under general anesthesia, relating their physical and psychic reactions to the different stages of stress. we studied 100 adult patients of both genders, who were divided into two groups: Group 1 - 22 patients without experience with surgery; Group 2 - 78 patients previously submitted to medium and major surgery. To investigate the stress, we used the Inventory of Stress Symptoms for Adults, developed by Lipp, the day before the procedure and two days and seven days after the operation. The comparison of groups with respect to gender, pain, and percentage of stress were performed using the Chi-square test, and for the age variable the Student's t test was used. Differences were considered significant at pdisorders.

  1. How to Submit a Revision and Tips on Being a Good Peer-Reviewer

    Science.gov (United States)

    Kotsis, Sandra V.; Chung, Kevin C.

    2014-01-01

    Many instructional guides have been published on how to write scientific papers. Likewise, many published articles have focused on the reasons why submitted manuscripts are rejected. However, fewer publications have been presented to guide authors on how to address reviewers’ comments in a manuscript revision. Even fewer papers counsel authors on how to deal with a rejection decision. In this paper, we will present a literature review on the strategies to get a paper accepted, despite an initial unfavorable review. We will share our experience on addressing reviewers’ comments to get a paper accepted and published. Finally, we will discuss the process of peer-review and offer tips on how to be an effective peer-reviewer. PMID:24675196

  2. Simplified Analytical Methods to Analyze Lock Gates Submitted to Ship Collisions and Earthquakes

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    Buldgen Loic

    2015-09-01

    Full Text Available This paper presents two simplified analytical methods to analyze lock gates submitted to two different accidental loads. The case of an impact involving a vessel is first investigated. In this situation, the resistance of the struck gate is evaluated by assuming a local and a global deforming mode. The super-element method is used in the first case, while an equivalent beam model is simultaneously introduced to capture the overall bending motion of the structure. The second accidental load considered in this paper is the seismic action, for which an analytical method is presented to evaluate the total hydrodynamic pressure applied on a lock gate during an earthquake, due account being taken of the fluid-structure interaction. For each of these two actions, numerical validations are presented and the analytical results are compared to finite-element solutions.

  3. FPIV study of gas entrainment by a hollow cone spray submitted to variable density

    Energy Technology Data Exchange (ETDEWEB)

    Prosperi, B. [UMR CNRS/INPT-UPS 5502, Institut de Mecanique des Fluides de Toulouse, Toulouse (France); P GS AD INCAS, Siemens VDO Automotive, 1, av Paul Ourliac, BP 1149, Toulouse (France); Delay, G.; Bazile, R. [UMR CNRS/INPT-UPS 5502, Institut de Mecanique des Fluides de Toulouse, Toulouse (France); Helie, J.; Nuglish, H.J. [P GS AD INCAS, Siemens VDO Automotive, 1, av Paul Ourliac, BP 1149, Toulouse (France)

    2007-08-15

    The gas entrainment in a hollow cone spray submitted to variable density is studied experimentally in order to better understand the effect on mixture formation. Particle image velocimetry on fluorescent tracers, associated with a specific processing of the instantaneous velocity fields have been applied to obtain measurement in the close vicinity of the spray edge. In the ''quasi-steady'' region of the spray, important effect of the ambient density on the mass flow rate of entrained gas (m{sub e}) have been pointed out. The axial evolution of m{sub e} is in good agreement with an integral model that takes the momentum exchange between phases into account. (orig.)

  4. Non-pharmacological measures in preterm newborns submitted to arterial puncture

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    Gleicia Martins de Melo

    Full Text Available ABSTRACT Objective: to assess pain in preterm newborns and to compare the neonatal and therapeutic variables with the total scores of the Neonatal Facial Coding System of preterm newborns submitted to arterial puncture exposed to music and 25% oral glucose. Method: a comparative study with 48 recordings of preterm newborns - Group 1, music (26; Group 2, glucose 25% (22 - individually analyzed by three trained nurses, after Kappa of at least 80%. Results: the variables and the pain scores of the groups did not present statistical significance (p < 0.05 according to the Neonatal Facial Coding System. 80.8% of the preterm infants in Group 1 had a higher quantitative score ≥ 3 in the neonatal variables (gender, type of delivery, and therapeutic variables (type of oxygen therapy, place of hospitalization, type of puncture. Conclusion: There was no difference when comparing the music and glucose 25% groups and the variables studied.

  5. Pain in preterm newborns submitted to music and 25% glucose intervention

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    Gleicia Martins de Melo

    2017-01-01

    Full Text Available to compare the pain response of preterm newborns submitted to arterial puncture who received musical intervention with those who received 25% glucose intervention. Methods: randomized, double-blind clinical trial; the sample consisted of 48 videos of preterm infants of the experimental group (music, n= 6, who listened to music for 10 minutes, and the control group (25% glucose, n=22, who received 25% glucose two minutes before puncture. The pain was evaluated by the Neonatal Facial Coding System at moments: Baseline, Treatment, Painful, Recovery 1 and Recovery 2. Results: there were similarities between groups at the moments Baseline, Recovery 1 and 2. A statistically significant difference was observed at the moment Treatment (p=0.014, Painful (p=0.029 for the control group. Conclusion: 25% glucose differed from music when comparing the pain response in the Treatment and Painful moments. Brazilian Registry of Clinical Trials: UTN: U1111-1123-4821.

  6. [Histopathological analysis of organs submitted by legal medicine experts in Baojii City: 358 forensic identification cases].

    Science.gov (United States)

    Dong, Du-xuan; Shi, Ping-xia; Li, Yun-li; Tian, San-hu; Yang, Jia; Gao, Gang; Zheng, Yun; Jia, Le; Ju, Hong-ya; Sun, Lu-ying; Chen, Ni; Wang, Xiao-bao

    2014-08-01

    To analyze pathological characteristics of organs recovered during forensic autopsy submitted by legal medicine experts. From Baoji city, 358 cases of forensic autopsy specimens from a series of routine exams were collected. And histopathological diagnoses were reviewed. Majority of the 358 cases were young men. The major causes of death were trauma, sudden death and poisoning. The cause of death was determined with histology in 250 cases. No typical histological changes were noted in 101 cases. The tissue autolysis and decomposition were present in 7 cases. The major pathological diagnosis was cardiovascular disease, followed by diseases in respiratory, nervous, and digestive systems. Forensic autopsy with its professional characteristics, is different from regular autopsy. When diagnosing cause of death by histopathological examination, pathologists should collaborate with legal medicine experts to know the details of the cases, circumstances surrounding the death, and specific forensic pathological characteristics.

  7. Autonomic dysfunction of rat jejunum submitted to cold ischemic preservation is prevented by heparin.

    Science.gov (United States)

    Taha, M O; Fraga, M M; Guimarães, F A; Jurkiewicz, A; Caricati-Neto, A

    2006-01-01

    Previous studies suggest that cold ischemic preservation (CIP) employed in small bowel transplantation promotes loss of intestinal motility due to severe lesions in autonomic enteric nerves. This autonomic dysfunction may be prevented by antioxidant agents. In this work, we investigated whether preservation with heparin prevented autonomic dysfunction of rat jejunum submitted to CIP for a long time. Jejunal segments (2 cm) of Wistar rats (12 to 16 weeks old) were preserved at 4 degrees C in Ringer's lactate solution without (-) or with (+) 100 UI/mL heparin (H). After preservation for 12 hours, H+ and H- preparations were mounted in parallel in isolated organ baths containing 10 mL Tyrode's solution at 37 degrees C for the study of neurogenic contractions evoked by electrical field stimulation (EFS; 10-30 Hz, 1-ms duration, 60 V) or by stimulation of nicotinic (NIC) or muscarinic (carbachol, CCh) cholinoceptors. The effects of NIC (hexamethonium, HEX) and muscarinic (atropine, ATR) antagonists were studied on these contractions. Contractions induced by EFS (30 Hz) were four times greater in H+ (1.02 +/- 0.12 g) versus H- (0.26 +/- 0.07 g), while contractions induced by NIC (1 mmol/L) were also four times higher in H+ (1.07 +/- 0.10 g) than H- (0.25 +/- 0.09 g) preparations. In addition, contractions induced by CCh (1 mmol/L) were two times higher in H+ (1.21 +/- 0.13 g) than in H- (0.65 +/- 0.10 g). EFS, NIC, and CCh contractions were inhibited by pretreatment of jejunum with HEX or ATR (1 mumol/L/30 min), in H+ and H-. These results indicated that addition of heparin to a preservation solution attenuated the autonomic dysfunction of rat jejunum submitted to CIP for a long time.

  8. Atenolol attenuates autonomic dysfunction of rat jejunum submitted to cold ischemic preservation.

    Science.gov (United States)

    Taha, M O; Fraga, M M; Guimarães, F A; Jurkiewicz, A; Caricati-Neto, A

    2006-01-01

    In vitro studies have demonstrated that cold ischemic preservation (CIP) employed in small bowel transplantation produces loss of intestinal motility due to severe lesions of autonomic enteric nerves and that this autonomic dysfunction is attenuated by antioxidant agents. In this work, we investigated whether preservation with atenolol attenuated autonomic dysfunction of rat jejunum submitted to long-term CIP. Jejunal segments (2 cm) of Wistar rats (12 to 16 weeks old) were surgically isolated and preserved at 4 degrees C in Ringer's lactate solution without (-) or with (+) 1 mumol/L atenolol (AT). After preservation for 12 hours, AT+ and AT- preparations were mounted in parallel in isolated organ baths containing 10 mL Tyrode's solution at 37 degrees C for the study of neurogenic contractions evoked by electrical field stimulation (EFS; 10 to 30 Hz, 1-ms duration, 60 V) or by stimulation with nicotinic (nicotine, NIC) or muscarinic (carbachol, CCh) cholinoceptor agents as well as nicotine (hexamethonium, HEX) and muscarinic (atropine, ATR) antagonists. Contractions induced by EFS (30 Hz) were 46% higher in AT+ (0.38 +/- 0.02 g) than AT- (0.26 +/- 0.01 g), while contractions induced by NIC (1 mmol/L) were 84% higher in AT+ (0.46 +/- 0.03 g) than in AT- (0.25 +/- 0.02 g). In addition, contractions induced by CCh (1 mmol/L) were 34% higher in AT+ (0.87 +/- 0.06 g) than in AT- (0.65 +/- 0.08 g). EFS-, NIC-, and CCh-induced contractions were inhibited by pretreatment of jejunum with HEX or ATR (1 mumol/30 min), in AT+ and AT-. These results suggest that addition of atenolol in the preservation solution attenuated autonomic dysfunction of rat jejunum submitted to long-term CIP.

  9. Prevalence of Bordetella pertussis and Bordetella parapertussis in Samples Submitted for RSV Screening

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    Walsh, Paul

    2008-08-01

    Full Text Available BACKGROUND: The clinical presentation of Bordetella pertussis can overlap with that of respiratory syncytial virus (RSV; however, management differs.HYPOTHESIS: First, the prevalence of B. pertussis is less than 2% among patients screened for RSV, and second the prevalence of B. parapertussis is also less than 2% among these patients.METHODS: Nasal washings submitted to a clinical laboratory for RSV screening were tested for B. pertussis and B. parapertussis, using species-specific real-time polymerase chain reaction (PCR assays. These were optimized to target conserved regions within a complement gene and the CarB gene, respectively. A Bordetella spp. genus-specific real-time PCR assay was designed to detect the Bhur gene of B. pertussis, B. parapertussis, and B. bronchiseptica. RSV A and B subtypes were tested by reverse transcription-PCR.RESULTS: Four hundred and eighty-nine clinical samples were tested. There was insufficient material to complete testing for one B. pertussis, 10 RSV subtype A, and four RSV subtype B assays. Bordetella pertussis was detected in 3/488 (0.6% (95% CI 0.1% to 1.8%, while B. parapertussis was detected in 5/489 (1.0% (95% CI 0.3% to 2.4%. Dual infection of B. pertussis with RSV and of B. parapertussis with RSV occurred in two and in three cases respectively. RSV was detected by PCR in 127 (26.5%.CONCLUSION: The prevalence of B. pertussis in nasal washings submitted for RSV screening was less than 2%. The prevalence of parapertussis may be higher than 2%. RSV with B. pertussis and RSV with B. parapertussis coinfection do occur.

  10. Tissue responses to postoperative laser therapy in diabetic rats submitted to excisional wounds.

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    Cristiano de Loura Santana

    Full Text Available In a previous study about low-level laser therapy biomodulation on a full-thickness burn model we showed that single and fractionated dose regimens increased wound healing and leukocyte influx similarly when compared with untreated control. In order to verify if this finding would be similar in an impaired wound model, we investigated the effect of single and multiple irradiations on wound closure rate, type of inflammatory infiltrate, myofibroblasts, collagen deposition, and optical retardation of collagen in diabetic rats. Female Wistar rats in the same estrous cycle had diabetes induced with streptozotocin and an 8-mm excisional wound performed with a punch. The experimental groups were: control group--untreated ulcer; single-dose group--ulcer submitted to single dose of diode laser therapy (λ = 660 ± 2 nm; P = 30 mW; energy density: 4 J/cm2 and fractionated-dose group--ulcer submitted to 1 J/cm2 laser therapy on Days 1, 3, 8, and 10. The ulcers were photographed on the experimental days and after euthanasia tissue samples were routinely processed for histological and immunohistochemistry analyses. Independently of the energy density, laser therapy accelerated wound closure by approximately 40% in the first three days in comparison to the control group. Laser therapy increased acute inflammatory infiltrate until Day 3. Both laser groups exhibited more myofibroblasts and better collagen organization than the control group. The findings demonstrate that low-level laser therapy in the immediate postoperative period can enhance the tissue repair process in a diabetes model. Similar effects were achieved with laser therapy applied a single time with an energy density of 4 J/cm2 and applied four times with an energy density of 1 J/cm2. The application of laser therapy in the inflammatory phase was the most important factor to the enhancement of the tissue repair process.

  11. Tissue responses to postoperative laser therapy in diabetic rats submitted to excisional wounds.

    Science.gov (United States)

    de Loura Santana, Cristiano; Silva, Daniela de Fátima Teixeira; Deana, Alessandro Melo; Prates, Renato Araujo; Souza, Amanda Pires; Gomes, Mariana Teixeira; de Azevedo Sampaio, Brunna Pileggi; Shibuya, Josiane Ferraretto; Bussadori, Sandra Kalil; Mesquita-Ferrari, Raquel Agnelli; Fernandes, Kristianne Porta Santos; França, Cristiane Miranda

    2015-01-01

    In a previous study about low-level laser therapy biomodulation on a full-thickness burn model we showed that single and fractionated dose regimens increased wound healing and leukocyte influx similarly when compared with untreated control. In order to verify if this finding would be similar in an impaired wound model, we investigated the effect of single and multiple irradiations on wound closure rate, type of inflammatory infiltrate, myofibroblasts, collagen deposition, and optical retardation of collagen in diabetic rats. Female Wistar rats in the same estrous cycle had diabetes induced with streptozotocin and an 8-mm excisional wound performed with a punch. The experimental groups were: control group--untreated ulcer; single-dose group--ulcer submitted to single dose of diode laser therapy (λ = 660 ± 2 nm; P = 30 mW; energy density: 4 J/cm2) and fractionated-dose group--ulcer submitted to 1 J/cm2 laser therapy on Days 1, 3, 8, and 10. The ulcers were photographed on the experimental days and after euthanasia tissue samples were routinely processed for histological and immunohistochemistry analyses. Independently of the energy density, laser therapy accelerated wound closure by approximately 40% in the first three days in comparison to the control group. Laser therapy increased acute inflammatory infiltrate until Day 3. Both laser groups exhibited more myofibroblasts and better collagen organization than the control group. The findings demonstrate that low-level laser therapy in the immediate postoperative period can enhance the tissue repair process in a diabetes model. Similar effects were achieved with laser therapy applied a single time with an energy density of 4 J/cm2 and applied four times with an energy density of 1 J/cm2. The application of laser therapy in the inflammatory phase was the most important factor to the enhancement of the tissue repair process.

  12. [Effects of parenteral glutamine in patients submitted to bone marrow transplantation].

    Science.gov (United States)

    Gómez Candela, C; Castillo, R; de Cos, A I; Iglesias, C; Martín, M C; Aguado, M J; Ojeda, E

    2006-01-01

    Bone marrow transplantation (BMT) is a therapy used for hematologic malignancies and solid tumors. Associated chemotherapy and radiotherapy to which these patients are submitted induce secondary effects, with a high metabolic stress. Glutamine is considered a conditionally essential amino acid, and has been shown effective in severe catabolic states. The aim of the study was to assess the effect of parenteral nutrition (PN) therapy supplemented with glutamine on duration of nutritional support in a group of patients with BMT. We have also analyzed associated complications, the nutritional status, the clinical course at 6 months, differences as to type of transplantation, and oral ingestion capability. This is a phase IV, randomized, double blind, and parallel clinical trial, done at a single center. The study was performed on 49 patients, 29% male and 71% female patients, with ages between 21-63 years, distributed in 3 diagnostic groups (leukemia, lymphoma, and solid tumors), and admitted to the Hematology Department of our Hospital. Fifty percent of the patients in each group have received PN supplemented with glutamine (0.4 g/kg/day of L-alanine-L-glutamine), and the other 50% have received standard PN. we have not found significant differences nor at the beginning nor at the end of the study between both groups with regards to studied variables. PN is and effective therapy for maintenance of the nutritional status in patients submitted to a therapy with a, highly catabolic effect such as BMT. Although we have not been able to show the efficacy of glutamine supplementation in this study with the used dose, it does have been effective in other reports.

  13. Clinical evaluation of patients submitted to osteogenic distraction in the lower limb at a university hospital

    Directory of Open Access Journals (Sweden)

    Francisco Macruz Baltazar Sampaio

    Full Text Available ABSTRACT OBJECTIVE: To evaluate the clinical characteristics from patients submitted to osteogenic distraction to correct bone gap at a university hospital. METHODS: Retrospective transversal study, with a convenience sample, from 2000 to 2012, evaluating clinical aspects of patients treated, submitted to osteogenic distraction (bone transport with Ilizarov's external fixation device. The chi-squared, Fisher's, and Mann-Whitney's U tests were used with a 5% level of significance (p < 0.05. RESULTS: 33 patients were studied, of whom 28 men (84.8%. The more frequent age was from 21 to 40 years. Most patients were from the metropolitan region of the capital (57.6%. The leg was the most affected limb (75.8%, and the left side was the most affected (66.7%. The most common cause was infected pseudoarthrosis (75.8%. The most common bone transportation type was bifocal (75.8%. Mean previous surgery at others institutions were 2.62 (1.93 standard deviation, and mean surgeries after treatment were 1.89 (1.29 standard deviation. Ilizarov's external fixation device was used for 1.94 years (1.34 mean deviation, from one to six years. The most common complications were pin infection (57.6%, equinus (30.3%, deep infection (24.2%, and shortening (21.2%. CONCLUSION: Osteogenic distraction for bone gaps were more frequent in young adults, men, in the leg, with bifocal transportation, after several previous surgeries, treated for a mean of two years, with many complications (infections were the most common.

  14. PHYSIOLOGICAL QUALITY OF Araucaria angustifolia (Bertol. Kuntze SEEDS SUBMITTED TO DIFFERENT STORAGE CONDITIONS AND ESCARIFICATION

    Directory of Open Access Journals (Sweden)

    Álvaro Valente Caçola

    2010-08-01

    Full Text Available The seeds of Araucaria angustifolia (Bertol. Kuntze are recalcitrants and, therefore, they lose rapidly the viability after the harvest, limiting their use for nursery production of seedlings. This work was carried out to investigate the effects of cold storage duration, conservation method, and escarification on germination and vigour of seeds of Araucaria angustifolia. The seeds were cold stored (0-1oC/90-95% RH for 0, 60, 120, and 180 days, under normal air condictions (NA, modified atmosphere (MA, and controlled atmosphere (CA storage. For each cold storage duration, after removal from cold storage, the seeds were submitted or not to scarification (by cutting a small portion of the apical seed tegument, avoiding the damage of the endosperm, letting the germinate in a chamber with controlled environment, in plastic trays filled with vermiculite, for 60 days. The experiment followed the completely randomized factorial design (4x3x2, with four cold storage durations (0, 60, 120, and 180 days, three storage methods (NA, MA, and CA, with or without escarification, and four replicates. There was a good preservation of physiological quality for seeds submitted to different conservation methods in cold storage along the 180-day period. However, there was a faster germination and initial growth of seedlings for seeds left in cold storage for 60 days than in seeds assessed at harvest or left in cold storage for 120-180 days. The NA storage of seeds in perfurated plastic bags was as efficient as MA and CA storage to preserve seeds quality. Seeds scarification increased vigor and promoted seedlings initial growth of Araucaria angustifolia after being removed from cold storage.

  15. Detection of vancomycin-resistant enterococci (VRE in stool specimens submitted for Clostridium difficile toxin testing

    Directory of Open Access Journals (Sweden)

    Sevim Özsoy

    Full Text Available Abstract The aim of this study was to determine the association between Clostridium difficile (C. difficile and vancomycin-resistant Enterococcus (VRE and efficacy of screening stools submitted for C. difficile toxin assay for prevalence of VRE. Between April 2012 and February 2014, 158 stool samples submitted for C. difficile toxin to the Marmara University Microbiology Laboratory, were included in the study. Stool samples were analyzed by enzyme immuno assay test; VIDAS (bioMerieux, France for Toxin A&B. Samples were inoculated on chromID VRE (bioMerieux, France and incubated 24 h at 37 °C. Manuel tests and API20 STREP (bioMerieux, France test were used to identify the Enterococci species. After the species identification, vancomycin and teicoplanin MIC's were performed by E test and molecular resistance genes for vanA vs vanB were detected by polymerase chain reaction (PCR. Of the 158 stool samples, 88 were toxin positive. The prevalence of VRE was 17%(n:19 in toxin positives however, 11.4% in toxin negatives(n:70. All VRE isolates were identified as Enterococcus faecium. These results were evaluated according to Fischer's exact chi-square test and p value between VRE colonization and C. difficile toxin positivity was detected 0.047 (p < 0.05. PPV and NPV were 79% and 47% respectively. In our study, the presence of VRE in C. difficile toxin positives is statistically significant compared with toxin negatives (p < 0.05. Screening for VRE is both additional cost and work load for the laboratories. Therefore VRE screening among C. difficile toxin positive samples, will be cost effective for determination of high risk patients in the hospitals especially for developing countries.

  16. Second neoplasms in adult patients submitted to haematopoietic stem cell transplantation.

    Science.gov (United States)

    Torrent, Anna; Ferrá, Christelle; Morgades, Mireia; Jiménez, María-José; Sancho, Juan-Manuel; Vives, Susana; Batlle, Montserrat; Moreno, Miriam; Xicoy, Blanca; Oriol, Albert; Ibarra, Gladys; Ribera, Josep-Maria

    2017-09-02

    Patients submitted to haematopoietic stem cell transplantation (HSCT) are at increased risk of late complications, such as second neoplasm (SN). The incidence and risk factors of SN in patients receiving HSCT at a single centre were analysed. The follow-up of adult patients who received a first HSCT (autologous [auto-HSCT] or allogeneic [allo-HSCT]) between January 2000 and December 2015 was reviewed. We collected their demographic characteristics, the primary disease and type of HSCT, and analysed the cumulative incidence of SN and their risk factors. Of 699 transplanted patients (auto-HSCT, n=451; allo-HSCT, n=248), 42 (6%) developed SN (17 haematological and 25 solid), 31 post-auto-HSCT and 11 post-allo-HSCT. Haematologic SN were more frequent after auto-HSCT than after allo-HSCT. The median time between HSCT and SN was 4.09 years [range 0.07-13.15], with no differences between auto-HSCT and allo-HSCT. The cumulative incidence of SN was 5% (95% CI 3-6) at 5 years, 7% (95% CI 5-10) at 10 years and 11% (95% CI 8-15) at 15 years, without differences according to the type of HSCT. Only the age over 40 years correlated with an increased risk of SN. In this series, the incidence of post-HSCT SN was similar to that previously described. Patients submitted to an auto-HSCT showed a higher frequency of haematologic SN. A higher incidence of SN was detected in patients older than 40 at the time of HSCT. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

  17. Marginal adaptation of class V composite restorations submitted to thermal and mechanical cycling

    Directory of Open Access Journals (Sweden)

    Denise Sa Maia CASSELLI

    2013-01-01

    Full Text Available Objective This study evaluated the effect of the margin location and an adhesive system on the marginal adaptation of composite restorations. Material and Methods Class V cavities were prepared in bovine teeth with the gingival margin on the dentin and the incisal margin on the enamel. The cavities were restored with a micro-hybrid composite resin using an etch-and-rinse [Single Bond 2 (SB] or a self-etching adhesive [Clearfil SE Bond (CL]. After finishing and polishing the restorations, epoxy replicas were prepared. The marginal adaptation was analyzed using scanning electronic microscopy (SEM, 500 x magnification. The higher gap width in each margin was recorded (T0. After the first evaluation, the samples were submitted to thermal cycling (2,000 cycles of 5°C±2°C followed by 55°C±2°C – T1 and mechanical cycling (100,000 cycles of 50 kN and 2 Hz – T2. Replicas of samples were rebuilt after each cycling and analyzed under SEM. The data were submitted to Mann-Whitney, Wilcoxon and Friedman testing (α=0.05. Results The SB presented higher gaps in the dentin than the enamel, while there was no difference between the substrate for the CL. In the dentin, the CL showed better marginal sealing than the SB. The opposite occurred in the enamel. There were no significant differences between the baseline, thermal and mechanical cycling for any experimental condition. Conclusions The outcomes of the present study showed that the adhesive system and margin location have an important effect on the marginal adaptation of composite restorations.

  18. Comparison of pregnancy rate between heifers, primiparous and multiparous Nellore submitted to artificial insemination fixed time

    Directory of Open Access Journals (Sweden)

    Gustavo Fernandes Grillo

    2015-10-01

    Full Text Available ABSTRACT. Grillo G.F., Guimarães A.L.L., Couto S.R.B., Abidu-Figueiredo M. & Palhano H.B. [Comparison of pregnancy rate between heifers, primiparous and multiparous Nellore submitted to artificial insemination fixed time.] Comparação da taxa de prenhez entre novilhas, primíparas e múltíparas da raça Nelore submetidas à inseminação artificial em tempo fixo. Revista Brasileira de Medicina Veterinária, 37(3:193-197, 2015. Departamento de Biologia Animal, Universidade Federal Rural do Rio de Janeiro, Rodovia BR 465, Km 7, Seropédica, RJ 23890-000, Brasil. Email: helcimarpalhano@gmail.com The aim of this study was evaluate the reproductive performance of cows from Nelore in a program fixed time artificial insemination (TAI pregnancy rates by comparing the categories of heifers, primiparous and multiparous. For the experiment, we used the Nellore females belonging to the same herd on property located in the coastal lowlands of the state of Rio de Janeiro, kept on pasture divided into three groups and submitted to the same synchronization protocol for TAI (D0- 2,0 mg of estradiol benzoate + bovine intravaginal device with 1.0g progesterone, D8- implant removal + 250μg of cloprostenol + 300 IU eCG, D9- 1.0 mg.of Bz. estradiol, D10- IATF. The groups were divided according to rank, in group I, n=150 heifers, group II, n=150 primiparous group III, n=181 multiparous all with body condition score (BCS with 1-5 scale ≥ 2,0. The overall pregnancy rate was 86% (129:150, 45.3% (41:150 and 76.8% (139:181 to groups I, II and III, respectively. Data were analyzed by chi-square test and the results indicated a statistically significant difference (P <0.05 between groups I and II and between groups II and III, with no difference between groups I and III. Therefore it was concluded that primiparous Nellore cows, showed poor reproductive performance in TAI program used when you compare to heifers and multiparous of the same race, which affected the

  19. 41 CFR 102-74.470 - What information must persons or organizations submit so that Federal agencies may consider their...

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What information must persons or organizations submit so that Federal agencies may consider their application for a permit? 102... Use of Public Buildings Application for Permit § 102-74.470 What information must persons or...

  20. 13 CFR 127.506 - May a joint venture submit an offer on an EDWOSB or WOSB requirement?

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false May a joint venture submit an offer on an EDWOSB or WOSB requirement? 127.506 Section 127.506 Business Credit and Assistance SMALL... project manager responsible for the performance of the contract; (d) The joint venture must perform the...

  1. 42 CFR 137.351 - Is a Self-Governance Tribe required to submit construction project progress and financial reports...

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Is a Self-Governance Tribe required to submit..., DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction Roles of Self-Governance Tribe in Establishing and Implementing Construction Project Agreements § 137.351 Is a Self-Governance Tribe required to...

  2. 75 FR 32673 - Finding of Failure To Submit Section 110 State Implementation Plans for Interstate Transport for...

    Science.gov (United States)

    2010-06-09

    ... Street, Kansas City, Kansas 66101-2907, (913) 551-7606. Monica Morales, Leader, Air Quality Planning... Mariana Islands, and Guam. Michael McGown, Manager, State and Tribal Air Alaska, Idaho, Oregon, Programs.... Instead, it would require states to develop, adopt, and submit SIPs to meet the requirements of section...

  3. 42 CFR 423.272 - Review and negotiation of bid and approval of plans submitted by potential Part D sponsors.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Review and negotiation of bid and approval of plans... and negotiation of bid and approval of plans submitted by potential Part D sponsors. (a) Review and negotiation regarding information, terms and conditions. CMS reviews the information filed under § 423.265(c...

  4. 76 FR 30707 - Information Collections Being Submitted for Review and Approval to the Office of Management and...

    Science.gov (United States)

    2011-05-26

    ... personally identifiable information derived from a customer's relationship with a provider of... COMMISSION Information Collections Being Submitted for Review and Approval to the Office of Management and... Management and Budget, via fax at 202-395-5167 or via e-mail to [email protected] and to the...

  5. 75 FR 68094 - Partial Grant and Partial Denial of Clean Air Act Waiver Application Submitted by Growth Energy...

    Science.gov (United States)

    2010-11-04

    ... Ethanol Content of Gasoline to 15 Percent; Decision of the Administrator; Notice #0;#0;Federal Register... Application Submitted by Growth Energy To Increase the Allowable Ethanol Content of Gasoline to 15 Percent...: Table of Contents I. Executive Summary MY2007 and Newer Light-Duty Motor Vehicles Durability/Long-Term...

  6. The Problem of Untested Sexual Assault Kits: Why Are Some Kits Never Submitted to a Crime Laboratory?

    Science.gov (United States)

    Patterson, Debra; Campbell, Rebecca

    2012-01-01

    Victims of sexual assault are often advised to seek postassault medical care to have a forensic exam, which includes evidence collection (termed a "sexual assault kit" [SAK]). After the exam, law enforcement personnel are supposed to submit the SAK to a crime laboratory for analysis. However, recent media reports suggest that in many communities…

  7. 78 FR 20164 - Self-Regulatory Organizations; NYSE Arca, Inc.; Response to Comments Submitted After the Issuance...

    Science.gov (United States)

    2013-04-03

    ... the exercise of redemption rights. C. Availability of Particular Copper Brands In comments submitted... concerning the availability of particular brands of copper, much less the availability of particular brands... (discussing the availability of the Trust's copper); and id. at 75486-87 (discussing the Commission's findings...

  8. Analysis of expressed sequence tags from Musa acuminata ssp. burmannicoides, var. Calcutta 4 (AA) leaves submitted to temperature stresses

    NARCIS (Netherlands)

    Santos, C.R.; Martins, N.F.; Horberg, H.M.; Almeida, E.R.P.; Coelho, M.C.F.; Togawa, R.; Silva, F.R.; Caetano, A.R.; Miller, R.N.G.; Souza, M.T.

    2005-01-01

    In order to discover genes expressed in leaves of Musa acuminata ssp. burmannicoides var. Calcutta 4 (AA), from plants submitted to temperature stress, we produced and characterized two full-length enriched cDNA libraries. Total RNA from plants subjected to temperatures ranging from 5°C to 25°C and

  9. 77 FR 43075 - Information Collection Submitted for Review and Approval to the Office of Management and Budget

    Science.gov (United States)

    2012-07-23

    ..., as amended. Total Annual Burden: 6,000 hours. Total Annual Cost: N/A. Privacy Impact Assessment: N/A. Nature and Extent of Confidentiality: Respondents are not being asked to submit confidential information... shape, depreciation reserve) required to verify the calculation of the carrier's depreciation expenses...

  10. 78 FR 68082 - Information Collection Activities: Oil and Gas Well-Workover Operations; Submitted for Office of...

    Science.gov (United States)

    2013-11-13

    ... to displace kill- weight fluids to an underbalanced state; submit detailed written procedures with... stands of drill pipe or workover string and drill collars that may be pulled prior to filling the hole..., actuations, inspections, and crew drills of the BOP system components and risers in the operations log during...

  11. 76 FR 3887 - Notice of Public Information Collection(s) Being Submitted for Review and Approval to the Office...

    Science.gov (United States)

    2011-01-21

    ... compatibility problems associated with reception of programming that is not scrambled or encrypted programming... information collection request (ICR) submitted to OMB: (1) Go to the Web page http://reginfo.gov/public/do/PRAMain , (2) look for the section of the Web page called ``Currently Under Review'', (3) click on the...

  12. 42 CFR 102.51 - Documentation a smallpox vaccine recipient must submit to be deemed eligible by the Secretary.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Documentation a smallpox vaccine recipient must..., DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX COMPENSATION PROGRAM Required Documentation To Be Deemed Eligible § 102.51 Documentation a smallpox vaccine recipient must submit to be deemed eligible by...

  13. 30 CFR 250.192 - What reports and statistics must I submit relating to a hurricane, earthquake, or other natural...

    Science.gov (United States)

    2010-07-01

    ... relating to a hurricane, earthquake, or other natural occurrence? 250.192 Section 250.192 Mineral Resources... statistics must I submit relating to a hurricane, earthquake, or other natural occurrence? (a) You must... tropical storm, or an earthquake. Statistics include facilities and rigs evacuated and the amount of...

  14. 76 FR 80884 - The Department of Commerce will submit to the Office of Management and Budget (OMB) for clearance...

    Science.gov (United States)

    2011-12-27

    ... Administration (NOAA). Title: Deep Seabed Mining Regulations for Exploration Licenses. OMB Control Number: 0648... licenses under the Deep Seabed Hard Mineral Resources Act. Any persons seeking a license must submit... Constitution Avenue NW., Washington, DC 20230 (or via the Internet at [email protected] ). Written comments and...

  15. 49 CFR Appendix B to Part 564 - Information To Be Submitted for Long Life Replaceable Light Sources of Limited Definition

    Science.gov (United States)

    2010-10-01

    .... 108 when substituted for an unmodified light source. If the Associate Administrator seeks public.... (e) Information submitted under this section is made available by NHTSA for public inspection as soon..., etc. V. Wiring Harness Connector to Bulb Base Interchangeability Dimensions and Tolerances A. Maximum...

  16. 20 CFR 266.6 - Information to be submitted by a representative payee-applicant; face-to-face interview.

    Science.gov (United States)

    2010-04-01

    ... representative payee-applicant; face-to-face interview. 266.6 Section 266.6 Employees' Benefits RAILROAD... be submitted by a representative payee-applicant; face-to-face interview. Before the Board selects a... listed in § 266.4 of this part. An employee of the Board may also conduct a face-to-face interview with...

  17. 76 FR 75894 - Information Collection Activities: Pipelines and Pipeline Rights-of-Way; Submitted for Office of...

    Science.gov (United States)

    2011-12-05

    ... application if using unbonded flexible pipe. 1007(a)(4)(i)(D) Provide results of third party IVA review in 40 your pipeline application if using unbonded flexible pipe. 1007(a)(4)(ii) Provide specified information... removed from service. 1007(a)(4) Submit required documentation for unbonded 150 flexible pipe. 1000-1019...

  18. 76 FR 8300 - Finding of Failure To Submit State Implementation Plan Revisions for Particulate Matter, PM-10...

    Science.gov (United States)

    2011-02-14

    ... AGENCY 40 CFR Part 52 Finding of Failure To Submit State Implementation Plan Revisions for Particulate Matter, PM-10, Maricopa County (Phoenix) PM-10 Nonattainment Area, AZ AGENCY: Environmental Protection... a state implementation plan (SIP) submittal required under the Clean Air Act (CAA or Act) for the...

  19. 30 CFR 285.615 - What other reports or notices must I submit to MMS under my approved SAP?

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    2010-07-01

    ... MMS under my approved SAP? 285.615 Section 285.615 Mineral Resources MINERALS MANAGEMENT SERVICE... CONTINENTAL SHELF Plans and Information Requirements Activities Under An Approved Sap § 285.615 What other reports or notices must I submit to MMS under my approved SAP? (a) You must notify MMS in writing within...

  20. 33 CFR 149.15 - What is the process for submitting alterations and modifications affecting the design and...

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false What is the process for submitting alterations and modifications affecting the design and construction of a deepwater port? 149.15...) DEEPWATER PORTS DEEPWATER PORTS: DESIGN, CONSTRUCTION, AND EQUIPMENT General § 149.15 What is the process...

  1. 33 CFR 150.820 - When must a written report of casualty be submitted, and what must it contain?

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false When must a written report of casualty be submitted, and what must it contain? 150.820 Section 150.820 Navigation and Navigable Waters... this section serves as the notice required under § 150.815. (d) The operator will ensure that the...

  2. 75 FR 31434 - Notice of Public Information Collection(s) Being Submitted for Review and Approval to the Office...

    Science.gov (United States)

    2010-06-03

    ...) look for the section of the web page called ``Currently Under Review'', (3) click on the downward...) click the ``Submit'' button to the right of the ``Select Agency'' box, and (6) when the list of FCC ICRs currently under review appears, look for the title of this ICR (or its OMB Control Number, if there is one...

  3. 76 FR 5158 - Notice of Public Information Collection(s) Being Submitted for Review and Approval to the Office...

    Science.gov (United States)

    2011-01-28

    ... its OMB Control Number, if there is one) and then click on the ICR Reference Number to view detailed...'', (3) click on the downward-pointing arrow in the ``Select Agency'' box below the ``Currently Under... the ``Select Agency'' box, (5) click the ``Submit'' button to the right of the ``Select Agency'' box...

  4. 77 FR 66823 - Freedom of Information Act Request for Papers Submitted to DARPA for the 2011 100 Year Starship...

    Science.gov (United States)

    2012-11-07

    ... of the Secretary Freedom of Information Act Request for Papers Submitted to DARPA for the 2011 100... to DARPA should be withheld in response to a request received by DARPA under the Freedom of..., 2012. ADDRESSES: Send written comments concerning this Freedom of Information Act request by email to...

  5. Peer-review and editorial process of the Ethiopian Medical Journal: ten years assessment of the status of submitted manuscripts.

    Science.gov (United States)

    Enquselassie, Fikre

    2013-04-01

    The Ethiopian Medical Journal (EMJ) is a peer-reviewed journal, now 50 years old. Many medical journals, including EMJ, follow a peer review system that has evolved from the 18th century process for reviewing submitted manuscripts. However, not much is known about peer review and editorial processes by many authors who submit manuscripts to the EMJ. To describe procedures related to EMJ peer-review and editorial decision making and asses the status of manuscripts submitted to the journal in the ten year period between 2001 and 2010. All the minutes of the editorial board meetings of the ten years period 2001-2010 and relevant documents were reviewed. The minutes have details including date of submission, dates to and from reviewers, date of decision, number of assigned peer reviewers and comments given by reviewers for each submitted manuscript. The length of time took in the processes and the decision made (accepted or rejected) for each submitted manuscript was calculated from the dates. All submitted manuscripts passed through three stages: internal per-review by an editorial board member, external peer review by selected reviewers and final editing stage by an assigned editorial member. A total of 615 manuscripts were submitted to EMJ in the ten years period 2001-2010. Five hundred and one (82.7%) manuscripts were accepted for publication by peer reviewers, while 74 (12.2%) were rejected and 31 (5.1%) were withdrawn. Acceptance was lowest among original articles (81.3%) followed by teaching or review articles (84.3%) and case reports (89.3%). Thirty-two (8.4%) manuscripts were accepted within 6 months following submission and 50% were accepted within in one year of submission. About 6% of manuscripts were delayed for more than two years with a maximum delay of 43 months. Even though, there is a decline trend on the delay of processing manuscripts, EMJ has long to go in order to improve the quality of the journal and shorten the slow peer review process

  6. Iliac artery myointimal hyperplasia in rabbits submitted to angioplasty and treated with Moringa oleifera

    Directory of Open Access Journals (Sweden)

    Jânio Cipriano Rolim

    Full Text Available Objective: to assess post-angioplasty myointimal hyperplasia in iliac artery of rabbits treated with extract of Moringa oleifera leaves. Methods : we conducted a randomized trial in laboratory animals for five weeks of follow-up, developed in the Vivarium of Pharmaceutical Technology Laboratory of the Universidade Federal da Paraíba. We used rabbits from the New Zealand breed, subjected to a hypercholesterolemic diet and angioplasty of the external iliac artery, randomized into two groups: M200 Group (n=10 - rabbits treated with 200mg/kg/day of Moringa oleifera leaves extract orally; SF group (n=10 - rabbits treated with 0.9% saline orally. After five weeks, the animals were euthanized and the iliac arteries prepared for histology. Histological sections were analyzed by digital morphometry. Statistical analysis was performed using the Student's t test. The significance level was 0.05. Results : there was no significant difference in myointimal hyperplasia between M200 and SF groups when comparing the iliac arteries submitted to angioplasty. Conclusion : there was no difference of myointimal hyperplasia between groups treated with saline and Moringa oleifera after angioplasty.

  7. Stress on external hexagon and Morse taper implants submitted to immediate loading.

    Science.gov (United States)

    Odo, Caroline H; Pimentel, Marcele J; Consani, Rafael L X; Mesquita, Marcelo F; Nóbilo, Mauro A A

    2015-01-01

    This study aimed to evaluate the stress distribution around external hexagon (EH) and Morse taper (MT) implants with different prosthetic systems of immediate loading (distal bar (DB), casting technique (CT), and laser welding (LW)) by using photoelastic method. Three infrastructures were manufactured on a model simulating an edentulous lower jaw. All models were composed by five implants (4.1 mm × 13.0 mm) simulating a conventional lower protocol. The samples were divided into six groups. G1: EH implants with DB and acrylic resin; G2: EH implants with titanium infrastructure CT; G3: EH implants with titanium infrastructure attached using LW; G4: MT implants with DB and acrylic resin; G5: MT implants with titanium infrastructure CT; G6: MT implants with titanium infrastructure attached using LW. After the infrastructures construction, the photoelastic models were manufactured and a loading of 4.9 N was applied in the cantilever. Five pre-determined points were analyzed by Fringes software. Data showed significant differences between the connection types (p < 0.0001), and there was no significant difference among the techniques used for infrastructure. The reduction of the stress levels was more influenced by MT connection (except for CT). Different bar types submitted to immediate loading not influenced stress concentration.

  8. Socio-demographic, clinical and laboratory profile of patients submitted to hemodialysis

    Directory of Open Access Journals (Sweden)

    Cristina Trevizan Telles

    2014-09-01

    Full Text Available The aim of the study was to characterize the patients with Chronic Kidney Disease submitted to hemodialysis in Rio Grande do Sul, Brazil, regarding the socio-demographic, clinical and laboratory characteristics. It is a cross-sectional study with 90 hemodialysis patients made in July and August 2013, through interviews. The results showed that 77.8% of the patients were male, with average age of 53.52 years and 66.7% were married. The average of schooling was 6.61 years; the Unified Health System assisted 86.7% of the cases. The average time of hemodialysis was 42.99 months. The most frequent etiology of the disease was systemic hypertension, 36.7%. The most used medicine were vitamins and minerals. Most laboratory exams were within the standards of reference. The data of the study can subside discussions among the health professionals involved in order to improve assistance and provide a better quality of life to the patient.

  9. Cannabidiol improves lung function and inflammation in mice submitted to LPS-induced acute lung injury.

    Science.gov (United States)

    Ribeiro, A; Almeida, V I; Costola-de-Souza, C; Ferraz-de-Paula, V; Pinheiro, M L; Vitoretti, L B; Gimenes-Junior, J A; Akamine, A T; Crippa, J A; Tavares-de-Lima, W; Palermo-Neto, J

    2015-02-01

    We have previously shown that the prophylactic treatment with cannabidiol (CBD) reduces inflammation in a model of acute lung injury (ALI). In this work we analyzed the effects of the therapeutic treatment with CBD in mice subjected to the model of lipopolysaccharide (LPS)-induced ALI on pulmonary mechanics and inflammation. CBD (20 and 80 mg/kg) was administered (i.p.) to mice 6 h after LPS-induced lung inflammation. One day (24 h) after the induction of inflammation the assessment of pulmonary mechanics and inflammation were analyzed. The results show that CBD decreased total lung resistance and elastance, leukocyte migration into the lungs, myeloperoxidase activity in the lung tissue, protein concentration and production of pro-inflammatory cytokines (TNF and IL-6) and chemokines (MCP-1 and MIP-2) in the bronchoalveolar lavage supernatant. Thus, we conclude that CBD administered therapeutically, i.e. during an ongoing inflammatory process, has a potent anti-inflammatory effect and also improves the lung function in mice submitted to LPS-induced ALI. Therefore the present and previous data suggest that in the future cannabidiol might become a useful therapeutic tool for the attenuation and treatment of inflammatory lung diseases.

  10. Financial analysis of diabetic patients hospitalizations submitted to lower limb amputation in a public hospital

    Directory of Open Access Journals (Sweden)

    Renata Santos Silva

    2015-03-01

    Full Text Available This study is a documental descriptive analysis which aimed to verify the cost established in 2006, in relation to the hospitalization of 21 diabetic patients submitted to the lower limb amputation in a public hospital and the value transferred by the Unified Health System (SUS regarding this procedure. Among the studied patients, 57.14% were female and 42.86% male, aged 40 to 90 years. The time of diagnosis varied from 5 to 25 years. The average of hospitalization was 14 days per patient. The cost to the hospital was R$ 99,455.74, average cost per patient was R$ 4,735.98. The total amount transferred by SUS to the hospital was R$ 27,740.15, a cost 3.6 times lower than the hospital costs. The SUS transferring is in accordance with the predetermined values for its table of procedure. Prevention is the only alternative to reduce the rate of amputation and improve survival of diabetes patients. It is necessary an early diagnosis and better control of diabetes mellitus with appropriate government and institutional policies.

  11. Diagnoses and clinical outcomes associated with surgically amputated feline digits submitted to multiple veterinary diagnostic laboratories.

    Science.gov (United States)

    Wobeser, B K; Kidney, B A; Powers, B E; Withrow, S J; Mayer, M N; Spinato, M T; Allen, A L

    2007-05-01

    Amputation is commonly performed in an attempt to both treat and diagnose conditions affecting the digits of cats. The records of multiple veterinary diagnostic laboratories were searched to identify submissions of amputated digits from cats. Eighty-five separate submissions were reviewed for diagnosis, age, sex, limb of origin, and digits affected; and the original submitting clinics were surveyed to determine clinical outcome. The Kaplan-Meier product-limit method was used to determine the disease-free interval and survival time. Neoplastic disease was identified in 63 of 85 submissions, with exclusively inflammatory lesions composing the other 22 cases. In 60 (95.2%) of the neoplastic cases, a malignant tumor was identified. Squamous cell carcinoma was the most commonly identified malignant tumor (n = 15; 23.8%) and was associated with a median survival time of 73 days. Other diagnoses included fibrosarcoma (n = 14; 22.2%); adenocarcinoma, likely metastases of a primary pulmonary neoplasm (n = 13; 20.6%); osteosarcoma (n = 5; 7.9%); mast cell tumor (n = 4; 6.3%); hemangiosarcoma (n = 5; 7.9%); malignant fibrous histiocytoma (n = 2; 3.2%); giant cell tumor of bone (n = 2; 3.2%); and hemangioma (n = 2; 3.2%). Giant cell tumor of bone has not been previously described in the digits of cats. Various neoplasms can occur in the digits of cats, and submission of the amputated digit for histopathologic diagnosis is essential to determine the histogenesis and predict the clinical outcome.

  12. Evaluation of nectar of kiwi (Actinidia deliciosa) submitted to gamma radiation

    Energy Technology Data Exchange (ETDEWEB)

    Harder, Marcia N C.; Toledo, Tais C.F. de; Ferreira, Andrea C.P.; Arthur, Valter [Centro de Energia Nuclear na Agricultura (CENA), Piracicaba, SP (Brazil). Lab. de Irradiacao de Alimentos e Radioentomologia]. E-mails: mnharder@cena.usp.br; tcftoled@cena.usp.br; andrea@dtr.com.br; arthur@cena.usp.br; Spoto, Marta H.F. [Escola Superior de Agricultura Luiz de Queiroz(ESALQ/USP), Piracicaba, SP (Brazil)]. E-mail: mhfspoto@esalq.usp.br

    2007-07-01

    The kiwi is an exotic fruit, it is pertaining the Actinidaceae family, possesses high nutritional value, being rich mainly in vitamin C and fibers, calcium, iron and phosphorus, what turns it a good nutritious option, presenting an important associated attribute the quality of the fruits and the flavor, what be comes it a fruit with great acceptance in the consuming markets, mainly children. The irradiation is an excellent method of conservation, as well as an accomplice to reinforce the action of other applied processes with the same purpose. The objective of this work was to formulate a sweetened drink, no alcoholic, starting from the kiwi (Actinidia deliciosa), to submit its at the gamma radiation for source of Co{sup 60} with doses of: 0 (control); 0.5; 1.0 and 2.0 kGy in a tax of dose of 0.712 kGy/hour, and subsequent physiochemical and sensorial analyses for detection of possible alterations provoked by the radiation. It is possible to conclude that the radiation in the doses used did not promote significant alterations in the physiochemical and sensorial characteristics of the kiwi nectar. (author)

  13. Findings From the INANE Survey on Student Papers Submitted to Nursing Journals.

    Science.gov (United States)

    Kennedy, Maureen Shawn; Newland, Jamesetta A; Owens, Jacqueline K

    Nursing students are often encouraged or required to submit scholarly work for consideration for publication but most manuscripts or course assignment papers do not meet journal standards and consume valuable resources from editors and peer reviewers. The International Academy of Nursing Editors (INANE) is a group of nurse editors and publishers dedicated to promoting best practices in publishing in the nursing literature. In August 2014, editors at INANE's annual meeting voiced frustrations over multiple queries, poorly written student papers, and lack of proper behavior in following through. This article describes the findings of a survey distributed to INANE members to seek feedback about submissions by students. Fifty-three (53) members responded to an online anonymous survey developed by the INANE Student Papers Work Group. Data were analyzed using descriptive statistics for Likert-type questions and content analysis of open-ended questions. Quantitative data revealed that most editors reported problems with student papers across all levels of graduate programs. Six themes emerged from the qualitative data: submissions fail to follow author guidelines; characteristics of student submissions; lack of professional behavior from students; lack of professional behavior from faculty; editor responses to student submissions; and faculty as mentors. These themes formed the basis for recommendations and strategies to improve student scholarly writing. Overall, editors endorsed supporting new scholars in the publication process but faculty engagement was integral to student success. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Bond strength of self-adhesive resin cements to composite submitted to different surface pretreatments

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    Victor Hugo dos Santos

    2014-02-01

    Full Text Available Objectives Extensively destroyed teeth are commonly restored with composite resin before cavity preparation for indirect restorations. The longevity of the restoration can be related to the proper bonding of the resin cement to the composite. This study aimed to evaluate the microshear bond strength of two self-adhesive resin cements to composite resin. Materials and Methods Composite discs were subject to one of six different surface pretreatments: none (control, 35% phosphoric acid etching for 30 seconds (PA, application of silane (silane, PA + silane, PA + adhesive, or PA + silane + adhesive (n = 6. A silicone mold containing a cylindrical orifice (1 mm2 diameter was placed over the composite resin. RelyX Unicem (3M ESPE or BisCem (Bisco Inc. self-adhesive resin cement was inserted into the orifices and light-cured. Self-adhesive cement cylinders were submitted to shear loading. Data were analyzed by two-way ANOVA and Tukey's test (p < 0.05. Results Independent of the cement used, the PA + Silane + Adhesive group showed higher microshear bond strength than those of the PA and PA + Silane groups. There was no difference among the other treatments. Unicem presented higher bond strength than BisCem for all experimental conditions. Conclusions Pretreatments of the composite resin surface might have an effect on the bond strength of self-adhesive resin cements to this substrate.

  15. Sex differences in brain cholinergic activity in MSG-obese rats submitted to exercise.

    Science.gov (United States)

    Sagae, Sara Cristina; Grassiolli, Sabrina; Raineki, Charlis; Balbo, Sandra Lucinei; Marques da Silva, Ana Carla

    2011-11-01

    Obesity is an epidemic disease most commonly caused by a combination of increased energy intake and lack of physical activity. The cholinergic system has been shown to be involved in the regulation of food intake and energy expenditure. Moreover, physical exercise promotes a reduction of fat pads and body mass by increasing energy expenditure, but also influences the cholinergic system. The aim of this study is to evaluate the interaction between physical exercise (swimming) and central cholinergic activity in rats treated with monosodium glutamate (MSG, a model for obesity) during infancy. Our results show that MSG treatment is able to induce obesity in male and female rats. Specifically, MSG-treated rats presented a reduced body mass and nasoanal length, and increased perigonadal and retroperitoneal fat pads in relation to the body mass. Physical exercise was able to reduce body mass in both male and female rats, but did not change the fat pads in MSG-treated rats. Increased food intake was only seen in MSG-treated females submitted to exercise. Cholinergic activity was increased in the cortex of MSG-treated females and physical exercise was able to reduce this activity. Thalamic cholinergic activity was higher in sedentary MSG-treated females and exercised MSG-treated males. Hypothalamic cholinergic activity was higher in male and female MSG-treated rats, and was not reduced by exercise in the 2 sexes. Taken together, these results show that MSG treatment and physical exercise have different effects in the cholinergic activity of males and females.

  16. Bone-implant contact around crestal and subcrestal dental implants submitted to immediate and conventional loading.

    Science.gov (United States)

    Pontes, Ana Emília Farias; Ribeiro, Fernando Salimon; Iezzi, Giovanna; Pires, Juliana Rico; Zuza, Elizangela Partata; Piattelli, Adriano; Marcantonio, Elcio

    2014-01-01

    The present study aims to evaluate the influence of apicocoronal position and immediate and conventional loading in the percentage of bone-implant contact (BIC). Thus, 36 implants were inserted in the edentulous mandible from six dogs. Three implants were installed in each hemimandible, in different positions in relation to the ridge: Bone Level (at crestal bone level), Minus 1 (one millimeter apical to crestal bone), and Minus 2 (two millimeters apical to crestal bone). In addition, each hemimandible was submitted to a loading protocol: immediate (prosthesis installed 24 hours after implantation) or conventional (prosthesis installed 120 days after implantation). Ninety days after, animals were killed, and implant and adjacent tissues were prepared for histometric analysis. BIC values from immediate loaded implants were 58.7%, 57.7%, and 51.1%, respectively, while conventional loaded implants were 61.8%, 53.8%, and 68.4%. Differences statistically significant were not observed among groups (P = 0.10, ANOVA test). These findings suggest that different apicocoronal positioning and loading protocols evaluated did not interfere in the percentage of bone-implant contact, suggesting that these procedures did not jeopardize osseointegration.

  17. Does a previous surgical experience interfere on psychic stress in patients submitted to major surgery?

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    Luiz Ronaldo Alberti

    Full Text Available OBJECTIVE: to evaluate the impact of stress in patients undergoing major surgeries under general anesthesia, relating their physical and psychic reactions to the different stages of stress. METHODS: we studied 100 adult patients of both genders, who were divided into two groups: Group 1 - 22 patients without experience with surgery; Group 2 - 78 patients previously submitted to medium and major surgery. To investigate the stress, we used the Inventory of Stress Symptoms for Adults, developed by Lipp, the day before the procedure and two days and seven days after the operation. The comparison of groups with respect to gender, pain, and percentage of stress were performed using the Chi-square test, and for the age variable the Student's t test was used. Differences were considered significant at p<0.05. RESULTS: the groups were not homogeneous as for the overall percentage of stress on the three measurements. G1 had decreased postoperative stress, whilst in G2 it increased. Psychological symptoms of stress prevailed in both groups. CONCLUSION: previous surgery reduced preoperative stress but did not affect postoperative emotional disorders.

  18. Analysis of the surface deformation of dental implants submitted to pullout and insertion test

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    Mariana Lima da Costa Valente

    2014-01-01

    Full Text Available Objective: The aim of the present study was to evaluate the possible deformations in the surface of dental implants submitted to pullout and insertion test in polyurethane synthetic bone, using scanning electron microscopy. Material and Methods: Four different types of implants were used: Master Screw, Master Porous, Master Conect AR and Master Conect Conical (n = 8. These implants were into the femoral head synthetic bone (Synbone and removed through the pullout test, performed with a universal testing machine (EMIC MEM 2000. All the screws, before and after the mechanical tests, were micro structurally analyzed in a Scanning Electron Microscope (SEM - Zeiss EVO50, utilizing a magnification of 35 times. The results were subjected to ANOVA and Tukey tests (α =0.05. Results: Only the Master Conect Conical and Master Porous implants presented statistically significant difference to pullout and maximum deformation (P = 0.014 and P = 0.009, respectively. The SEM images did not show morphological changes of the implants when compared before and after the mechanical tests. Conclusion: We concluded that Master Porous presented higher pullout resistance, suggesting a greater primary stability.

  19. Chicken Meat Submitted to Gamma Radiation and Packed with or without Oxygen

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    K Pelicia

    2015-06-01

    Full Text Available The objective of this study was to evaluate the effects on gamma radiation levels on the physical and microbiological characteristics of chicken breast meat. A completely randomized experimental design in a 4x2x3 factorial arrangement was adopted. Treatments consisted of four radiation concentrations (0, 2, 4, or 8kGy, two package sealing methods (with or without vacuum, and three storage times (01, 07, or 14 days, with ten replicates each, totaling 240 chicken breast fillets. Packaging and radiation had no influence (p>0.05 on chicken breast meat pH, water retention capacity, or presence of Salmonella spp. Breast fillets not submitted to radiation and vacuum packed presented higher water retention capacity (p<0.05 than those radiated at 4kGy and vacuum packed. Drip loss in fillets radiated at 8kGy and not vacuum packed was higher (p<0.05 than in non-radiated and non-vacuum packed fillets; however, both were not different from the other treatments. Coliform presence increased with storage time in non-radiated samples; however, when these were vacuum-packed, their development was slower. The results of the present experiment suggest that the use of a low radiation dose (2kGy, combined with vacuum packing, may minimize the harmful effects of storage on chicken breast fillets.

  20. [Long-term adverse effects on bladder filling phase in males submitted to the pelvic radiotherapy].

    Science.gov (United States)

    Méndez-Rubio, Santiago; Salinas-Casado, Jesús; Vírseda-Chamorro, Miguel; Esteban-Fuertes, Manuel; Menéndez-Sánchez, Pablo; Moreno-Sierra, Jesús

    2015-09-01

    To describe and quantify the long-term adverse effects on filling phase of lower urinary tract function in males submitted to radiotherapy. We performed a retrospective comparative study on a cohort of 99 men undergoing EBRT a mean of 4.7 years before for clinically localized prostate, rectum or colon neoplasia, and another cohort formed by 97 men over 50 years who did not undergo radiotherapy. Cystometric bladder capacity and bladder capacity at first voiding desire were significantly lower in the radiotherapy group. Univariate analysis showed that the radiotherapy group evinced a risk to present a diminished compliance of 3.5 times more and 9.3 times more to find stress urinary incontinence, but we did not found increased risk for detrusor overactivity. In multivariate analysis the history of radical surgery acted as a confounding factor in the risk of stress urinary incontinence, but not to suffer diminished bladder compliance. The main long-term adverse effect of pelvic radiotherapy on male bladder function during filling is the increased risk of low bladder compliance.

  1. Reproductive efficiency of asymptomatic Theileria equi carriers mares submitted to an embryo transfer program

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    Luciana L. Bezerra

    2015-03-01

    Full Text Available This study aimed to assess and evaluate the effects of Theileria equi infection on embryonic recovery, gestation and early embryonic loss. Thirteen Mangalarga Marchador Theileria equi positive donors (diagnosed through nested-PCR and 40 embryos receptors were used. Donors were submitted to two embryo collections in two consecutive estrous cycles (GId; after, the same mares were treated with imidocarb dipropionate (1.2mg/kg IM. in order to collect more embryos in two more estrous cycles (GIId. Receptors were divided into two groups (control and with treated with 20 animals each, where one group was the control (GIr and the other one (GIIr treated with 1.2mg/kg IM of imidocarb dipropionate assessing the gestation rate at 15, 30, 45 and 60 days. After 52 embryo collections, the embryonic recovery rates were 53.84% (14/26 and 65.38% (17/26 (p> 0.05 for GId and GIId, respectively. The gestation rate was 70% (14/20 (p>0.05 at 15, 30, 45 and 60 days in group GIr and for GIIr was 85% (17/20 (p>0.05 at 15 days, 80% (16/20 (p>0.05 at 30, 45 and 60 days. The treatment with imidocarb dipropionate did not cause significant improvement in the reproductive efficiency at an ET program.

  2. Modeling the methane hydrate formation in an aqueous film submitted to steady cooling

    Energy Technology Data Exchange (ETDEWEB)

    Avendano-Gomez, J.R. [ESIQIE, Laboratorio de Ingenieria Quimica Ambiental, Mexico (Mexico). Inst. Politecnico Nacional; Garcia-Sanchez, F. [Laboratorio de Termodinamica, Mexico (Mexico). Inst. Mexicano del Petroleo; Gurrola, D.V. [UPIBI, Laboratorio de Diseno de Plantas, Mexico (Mexico). Inst. Politecnico Nacional

    2008-07-01

    Gas hydrates, or clathrate hydrates, are ice-like compounds that results from the kinetic process of crystallization of an aqueous solution supersaturated with a dissolved gas. This paper presented a model that took into account two factors involved in the hydrate crystallization, notably the stochastic nature of crystallization that causes sub-cooling and the heat resulting from the exothermic enthalpy of hydrate formation. The purpose of this study was to model the thermal evolution inside a hydrate forming system which was submitted to an imposed steady cooling. The study system was a cylindrical thin film of aqueous solution at 19 Mpa. The study involved using methane as the hydrate forming molecule. It was assumed that methane was homogeneously dissolved in the aqueous phase. Ethane hydrate was formed through a kinetic process of nucleation and crystallization. In order to predict the onset time of nucleation, the induction time needed to be considered. This paper discussed the probability of nucleation as well as the estimation of the rate of nucleation. It also presented the mathematical model and boundary conditions. These included assumptions and derivation of the model; boundary conditions; initial conditions; and numerical solution of the model equation. It was concluded that the heat source must be considered when investigating crystallization effects. 34 refs., 2 tabs., 2 figs.

  3. How the scientific community reacts to newly submitted preprints: article downloads, Twitter mentions, and citations.

    Science.gov (United States)

    Shuai, Xin; Pepe, Alberto; Bollen, Johan

    2012-01-01

    We analyze the online response to the preprint publication of a cohort of 4,606 scientific articles submitted to the preprint database arXiv.org between October 2010 and May 2011. We study three forms of responses to these preprints: downloads on the arXiv.org site, mentions on the social media site Twitter, and early citations in the scholarly record. We perform two analyses. First, we analyze the delay and time span of article downloads and Twitter mentions following submission, to understand the temporal configuration of these reactions and whether one precedes or follows the other. Second, we run regression and correlation tests to investigate the relationship between Twitter mentions, arXiv downloads, and article citations. We find that Twitter mentions and arXiv downloads of scholarly articles follow two distinct temporal patterns of activity, with Twitter mentions having shorter delays and narrower time spans than arXiv downloads. We also find that the volume of Twitter mentions is statistically correlated with arXiv downloads and early citations just months after the publication of a preprint, with a possible bias that favors highly mentioned articles.

  4. How the scientific community reacts to newly submitted preprints: article downloads, Twitter mentions, and citations.

    Directory of Open Access Journals (Sweden)

    Xin Shuai

    Full Text Available We analyze the online response to the preprint publication of a cohort of 4,606 scientific articles submitted to the preprint database arXiv.org between October 2010 and May 2011. We study three forms of responses to these preprints: downloads on the arXiv.org site, mentions on the social media site Twitter, and early citations in the scholarly record. We perform two analyses. First, we analyze the delay and time span of article downloads and Twitter mentions following submission, to understand the temporal configuration of these reactions and whether one precedes or follows the other. Second, we run regression and correlation tests to investigate the relationship between Twitter mentions, arXiv downloads, and article citations. We find that Twitter mentions and arXiv downloads of scholarly articles follow two distinct temporal patterns of activity, with Twitter mentions having shorter delays and narrower time spans than arXiv downloads. We also find that the volume of Twitter mentions is statistically correlated with arXiv downloads and early citations just months after the publication of a preprint, with a possible bias that favors highly mentioned articles.

  5. The action of demineralized bovine bone matrix on bone neoformation in rats submitted to experimental alcoholism

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    R.L. Buchaim

    2013-06-01

    Full Text Available The objective of this study was to evaluate whether demineralized bovine bone (Gen-ox® alters bone neoformation in rats submitted to alcoholism. Forty male rats were separated into two groups of 20 rats and distributed as follows: Group E1, which received 25% ethanol and a surgical cavity filled only by a blood clot, and Group E2, which received 25% ethanol and a surgical cavity filled with Gen-ox®. The animals were euthanized at 10, 20, 40 and 60 days after surgery and necropsy was performed. The histomorphological and histometric analyses of the area of connective tissue and bone neoformation showed that the reorganization of the bone marrow and full repair of the surgical cavity in Group E1 occurred more quickly than in Group E2. It was also noted that in the final period the animals in Group E2 showed areas of connective tissue and thick bone trabeculae around the particles of the implant. It can be concluded that the use of Gen-ox® delayed the process of bone repair in alcoholic rats, although it can be used as filling material because it shows osteoconductive activity, as evidenced by bone tissue formation around the graft particles.

  6. Parasitic Infections Based on 320 Clinical Samples Submitted to Hanyang University, Korea (2004-2011)

    Science.gov (United States)

    Choi, Sung-Chul; Lee, Soo-Young; Song, Hyun-Ouk; Ryu, Jae-Sook

    2014-01-01

    We analyzed 320 clinical samples of parasitic infections submitted to the Department of Environmental Biology and Medical Parasitology, Hanyang University from January 2004 to June 2011. They consisted of 211 nematode infections, 64 trematode or cestode infections, 32 protozoan infections, and 13 infections with arthropods. The nematode infections included 67 cases of trichuriasis, 62 of anisakiasis (Anisakis sp. and Pseudoterranova decipiens), 40 of enterobiasis, and 24 of ascariasis, as well as other infections including strongyloidiasis, thelaziasis, loiasis, and hookworm infecions. Among the cestode or trematode infections, we observed 27 cases of diphyllobothriasis, 14 of sparganosis, 9 of clonorchiasis, and 5 of paragonimiasis together with a few cases of taeniasis saginata, cysticercosis cellulosae, hymenolepiasis, and echinostomiasis. The protozoan infections included 14 cases of malaria, 4 of cryptosporidiosis, and 3 of trichomoniasis, in addition to infections with Entamoeba histolytica, Entamoeba dispar, Entamoeba coli, Endolimax nana, Giardia lamblia, and Toxoplasma gondii. Among the arthropods, we detected 6 cases of Ixodes sp., 5 of Phthirus pubis, 1 of Sarcoptes scabiei, and 1 of fly larva. The results revealed that trichuriasis, anisakiasis, enterobiasis, and diphyllobothriasis were the most frequently found parasitosis among the clinical samples. PMID:24850969

  7. Behavioral profile of Macrobrachium rosenbergii in mixed and monosex culture submitted to shelters of different colors

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    Daniele Bezerra Santos

    2015-07-01

    Full Text Available Current research analyzed the behavioral activities of Macrobrachium rosenbergii and its preference for colored shelters in male monosex, female monosex and mixed culture. Ten shrimps m-2 were maintained in eight 250-L aquaria. Three artificial shelters, colored red, black and orange, were placed in each aquarium. Four aquaria were maintained in light/dark photoperiod respectively between 6h00 am and 6h00 pm and between 6h00 pm and 6h00 am, whereas the other four aquaria were submitted to an inverted photoperiod. The animals were observed for 30 days by Focal Animal Method for 15 minutes, with instantaneous recording every 60 seconds, at six different instances within the light and dark phases. Preference for black shelters occurred in male monosex and mixed cultures, whereas red and orange shelters were the preference of female monosex. M. rosenbergii kept in the shelter mostly during the light phase in male monosex and mixed populations. Results suggest that black, red and orange shelters may improve the animals' well-being in the culture since aggressive encounters would decrease, especially during the light phase.

  8. Iliac artery myointimal hyperplasia in rabbits submitted to angioplasty and treated with Moringa oleifera.

    Science.gov (United States)

    Rolim, Jânio Cipriano; Nogueira, Manoel Ricardo Sena; Lima, Paulo Roberto da Silva; Bandeira, Francisco Chavier Vieira; Pordeus, Mizael Armando Abrantes; Castro, Aldemar Araújo; Pitta, Guilherme Benjamin; Diniz, Margareth de Fátima Formiga Melo; Pereira, Adamastor Humberto

    2016-02-01

    to assess post-angioplasty myointimal hyperplasia in iliac artery of rabbits treated with extract of Moringa oleifera leaves. we conducted a randomized trial in laboratory animals for five weeks of follow-up, developed in the Vivarium of Pharmaceutical Technology Laboratory of the Universidade Federal da Paraíba. We used rabbits from the New Zealand breed, subjected to a hypercholesterolemic diet and angioplasty of the external iliac artery, randomized into two groups: M200 Group (n=10) - rabbits treated with 200mg/kg/day of Moringa oleifera leaves extract orally; SF group (n=10) - rabbits treated with 0.9% saline orally. After five weeks, the animals were euthanized and the iliac arteries prepared for histology. Histological sections were analyzed by digital morphometry. Statistical analysis was performed using the Student's t test. The significance level was 0.05. there was no significant difference in myointimal hyperplasia between M200 and SF groups when comparing the iliac arteries submitted to angioplasty. there was no difference of myointimal hyperplasia between groups treated with saline and Moringa oleifera after angioplasty.

  9. Use of flunixin meglumine in Santa Inês ewes submitted to laparoscopic and transcervical insemination

    Directory of Open Access Journals (Sweden)

    Renato Travassos Beltrame

    2014-10-01

    Full Text Available The objective of this work was to evaluate the use of flunixim meglumine in Santa Ines ewes submitted to artificial insemination (AI. Forty-four Santa Inês ewes were synchronized and inseminated at fixed times, by the transcervical or laparoscopic route, between 52 and 58 hours after sponge removal. The ewes were split into two treatment groups, to receive intramuscular injections of 2 mL of saline (control treatment or 2.2 mg/kg flunixin meglumine (FM treatment, twice a day between days 9 and 19 after AI. The pregnancy diagnosis was performed by ultrasound 30 days after the AI. The chi-square test was used to compare the pregnancy rate between the control and flunixin meglumine treatment and between type of insemination, while the t-test, at 5% probability was used to compare the average weight and body condition, using the SAS statistical software. Flunixin meglumine was not effect in increasing the pregnancy rate in Santa Ines ewes undergoing laparoscopic and transcervical insemination.

  10. Leaf anatomy of emerald grass submitted to quantitative application of herbicides

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    Renata Pereira Marques

    2016-08-01

    Full Text Available The aim of this work was to evaluate the selectivity of herbicides applied in post-emergence on Zoysia japonica Steud (Poaceae and determine associations with the leaf anatomy of this grass. The experimental design was randomized blocks with four replications. The treatments were the application of the herbicides bentazon (720 g ha-1, nicosulfuron (50 g ha-1, halosulfuron (112.5 g ha-1, oxadiazon (875 g ha-1 and 2.4-D (698 g ha-1, plus a control treatment without herbicide application. Phytotoxicity was assessed every seven days after application (DAA of the herbicides until the symptoms disappeared. Foliar anatomical analyses of the leaves in the collected grass were conducted until the 35th DAA. The quantitative characters of the keel and wing region of the blade of Z. japonica were assessed, as well as the biometric characters, which were submitted to an analysis of variance F test, and the averages were compared by Tukey’s test at a probability of 5%. The values of the anatomical characters of the foliar blade were tested by cluster analysis. The application of herbicides did not negatively influence the height of the plants but did reduce their dry mass. Toxic symptoms disappeared after 21 DAA, with the only symptoms of injury observed in plants treated with the herbicides oxadiazon and nicosulfuron. In addition, the cluster analysis indicated the formation of a unique discriminatory group. Thus, the results show that the herbicides applied to Z. japonica were selective for the species.

  11. How the Scientific Community Reacts to Newly Submitted Preprints: Article Downloads, Twitter Mentions, and Citations

    Science.gov (United States)

    Shuai, Xin; Pepe, Alberto; Bollen, Johan

    2012-01-01

    We analyze the online response to the preprint publication of a cohort of 4,606 scientific articles submitted to the preprint database arXiv.org between October 2010 and May 2011. We study three forms of responses to these preprints: downloads on the arXiv.org site, mentions on the social media site Twitter, and early citations in the scholarly record. We perform two analyses. First, we analyze the delay and time span of article downloads and Twitter mentions following submission, to understand the temporal configuration of these reactions and whether one precedes or follows the other. Second, we run regression and correlation tests to investigate the relationship between Twitter mentions, arXiv downloads, and article citations. We find that Twitter mentions and arXiv downloads of scholarly articles follow two distinct temporal patterns of activity, with Twitter mentions having shorter delays and narrower time spans than arXiv downloads. We also find that the volume of Twitter mentions is statistically correlated with arXiv downloads and early citations just months after the publication of a preprint, with a possible bias that favors highly mentioned articles. PMID:23133597

  12. Sodium bicarbonate as prevention of metabolic acidosis in sheep submitted to experimental ruminal acidosis

    Directory of Open Access Journals (Sweden)

    Luciane M. Laskoski

    2014-09-01

    Full Text Available The aim of this study was to evaluate the preventive effect of sodium bicarbonate on systemic acidosis due to ruminal acidosis, which was induced by ingestion of concentrate after prolonged fasting. Fourteen sheep were divided into three experimental groups: control group (Cg, with four sheep, submitted to fasting without development of ruminal acidosis; no-treated group (NTg, with five sheep with rumen acidosis without preventive treatment; and treated group (Tg, with five sheep with rumen acidosis and preventively treated with sodium bicarbonate. Assessments of ruminal pH and arterial hemogasometry were performed for 48 hours after ingestion of the concentrate. There was a reduction in the ruminal pH in all groups, whereas the Cg showed a reduction only after 24 hours. A reduction in the arterial pH, bicarbonate and base excess in all groups was also noted, indicating systemic metabolic acidosis, but the NTg presented the greatest alteration. It is concluded that sodium bicarbonate prevents systemic metabolic acidosis, reducing its severity in sheep subjected to ruminal acidosis.

  13. Germination and growth of white oat genotypes seedlings submitted to salt stress

    Directory of Open Access Journals (Sweden)

    Fabiana Carrett Timm

    2015-10-01

    Full Text Available The white oat is a winter crop used in succession to rice cultivation, subject to salt stress due to the accumulation of salts in the soil, especially in the southern Rio Grande do Sul. The objective of this work was to evaluate the seed germination, initial growth of the nine genotypes seedling of white oat and to identify contrasting genotypes, well as to identify the genotypes contrasting to character for salt tolerance character. For this, the genotypes were submitted to different salt concentrations (0, 25, 50, 75 and 100 mM de NaCl per liter of water, being analyzed the following variables: percentage of germination, first counting germination, index germination speed, length, shoots and roots dry mass of seedlings. The results may imply that seed germination that the percentage of germination was slightly decreased compared to the shoot growth and roots that have been greatly reduced with increasing salt concentrations. The root length and shoot length is in promising variables in the separation of genotypes in relation to different salt concentrations, allowing you to select two contrasting genotypes to salinity, the (URS 22 characterized as tolerant and (UPF 16 as sensitive.

  14. Bone-Implant Contact around Crestal and Subcrestal Dental Implants Submitted to Immediate and Conventional Loading

    Directory of Open Access Journals (Sweden)

    Ana Emília Farias Pontes

    2014-01-01

    Full Text Available The present study aims to evaluate the influence of apicocoronal position and immediate and conventional loading in the percentage of bone-implant contact (BIC. Thus, 36 implants were inserted in the edentulous mandible from six dogs. Three implants were installed in each hemimandible, in different positions in relation to the ridge: Bone Level (at crestal bone level, Minus 1 (one millimeter apical to crestal bone, and Minus 2 (two millimeters apical to crestal bone. In addition, each hemimandible was submitted to a loading protocol: immediate (prosthesis installed 24 hours after implantation or conventional (prosthesis installed 120 days after implantation. Ninety days after, animals were killed, and implant and adjacent tissues were prepared for histometric analysis. BIC values from immediate loaded implants were 58.7%, 57.7%, and 51.1%, respectively, while conventional loaded implants were 61.8%, 53.8%, and 68.4%. Differences statistically significant were not observed among groups (P=0.10, ANOVA test. These findings suggest that different apicocoronal positioning and loading protocols evaluated did not interfere in the percentage of bone-implant contact, suggesting that these procedures did not jeopardize osseointegration.

  15. Wood quality of Eucalyptus grandis dominant and average trees submitted to drying

    Directory of Open Access Journals (Sweden)

    Joel Telles de Souza

    2012-03-01

    Full Text Available This study determined, in trees of dominant and average diameter, the influence of air seasoning followed by kiln drying in the sawn wood quality of 14 years old stand of Eucalyptus grandis W. Hill ex Maiden, located in Capivari do Sul municipality, state of Rio Grande do Sul. The sampling of trees was performed after a pilot inventory on the basis of the dominant and average diameter at breast height (DBH. After cutting down the trees, there were selected the logs located between the DBH and 25% of commercial height. The logs were then sawn using into boards that were submitted to air seasoning from green up to 18% of moisture content, followed by kiln drying until 13% of moisture content. End checking and board crook were evaluate after sawing, following air seasoning and kiln drying. The results indicate that, both for dominant and average trees, end checking and board crook were not influenced by different wood process stage. However, the contrast between dominant and average trees shows that the magnitude of defects is higher in the average trees.

  16. Relationship of age to outcome and clinicopathologic findings in men submitted to radical prostatectomy

    Directory of Open Access Journals (Sweden)

    Athanase Billis

    2005-12-01

    Full Text Available OBJECTIVE: It is controversial whether age is associated with higher grade and worse outcome. Some studies have not found age to be related to outcome nor younger age to be associated with better response to therapy. MATERIALS AND METHODS: The study population consisted of 27 patients aged 55 years or younger and 173 patients 56 years or older submitted to radical prostatectomy. The variables studied were preoperative PSA, time to PSA progression following radical prostatectomy and pathologic findings in surgical specimens: Gleason score, Gleason predominant grade, positive surgical margins, tumor extent, extraprostatic extension (pT3a, and seminal vesicle invasion (pT3b. RESULTS: Comparing patients aged 55 years or younger and 56 years or older, there was no statistically significant difference for all variables studied: preoperative PSA (p = 0.4417, Gleason score (p = 0.3934, Gleason predominant grade (p = 0.2653, tumor extent (p = 0.1190, positive surgical margins (p = 0.8335, extraprostatic extension (p = 0.3447 and seminal vesicle invasion (p > 0.9999. During the study period, 44 patients (22% developed PSA progression. No difference was found in the time to biochemical progression between men aged 55 years or younger and 56 years or older. CONCLUSION: Our findings suggest that age alone do not influence the biological aggressiveness of prostate cancer.

  17. Evaluation of entrance surface-skin doses in animals submitted on exams of abdomen in veterinary radiology using Tl dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Veneziani, G. R.; Matsushima, L. C.; Campos, L. L. [Instituto de Pesquisas Energeticas e Nucleares, Gerencia de Metrologia das Radiacoes / CNEN, Av. Lineu Prestes 2242, Cidade Universitaria, 05508-000 Sao Paulo (Brazil); Filho, A. M., E-mail: venezianigr@gmail.com [Centro Universitario de Rio Petro - UNIRP, Rodovia Br 153 (Transbrasiliana), Km. 69 Sao Jose do Rio Preto, Sao Paulo (Brazil)

    2014-08-15

    The radiation protection has recently gained considerable attention in human medicine. In veterinary medicine has been some advances in radiodiagnostic and therapy for domestic animal like dogs and cats. It is notable the increase of the costs with domestic animals that are considered, by many people in the whole world, like members of family. However, an important parameter that must be taken into account is the increasing use of computed tomography and other equipment s that uses ionizing radiation, which may lead to comparatively high exposure of critical organs. The radiation dose is determined by the balance between therapeutic benefit and possible damage to surrounding normal tissues. This study aimed the evaluation of entrance surface-skin doses in dogs submitted to radiodiagnostic procedures of abdomen using the technique of thermoluminescent dosimetry (TLD). The radiation doses were measured using thermoluminescent dosimeters of LiF:Mg,Ti (TLD 100) and a dog phantom made with a plastic container, proportional to the dog size, fulfilled with water. (Author)

  18. 21 CFR 803.11 - What form should I use to submit reports of individual adverse events and where do I obtain these...

    Science.gov (United States)

    2010-04-01

    ... REPORTING General Provisions § 803.11 What form should I use to submit reports of individual adverse events... individual adverse events and where do I obtain these forms? 803.11 Section 803.11 Food and Drugs FOOD AND... submit all reports of individual adverse events on FDA MEDWATCH Form 3500A or in an electronic equivalent...

  19. 25 CFR 1000.50 - What must a Tribe/Consortium seeking a planning grant submit in order to meet the planning phase...

    Science.gov (United States)

    2010-04-01

    ... submit in order to meet the planning phase requirements? 1000.50 Section 1000.50 Indians OFFICE OF THE... seeking a planning grant submit in order to meet the planning phase requirements? A Tribe/Consortium must... the Tribe/Consortium is free from material audit exceptions. In order to meet this requirement, a...

  20. 24 CFR 1000.506 - If the TDHE is the recipient, must it submit its monitoring evaluation/results to the Indian tribe?

    Science.gov (United States)

    2010-04-01

    ... it submit its monitoring evaluation/results to the Indian tribe? 1000.506 Section 1000.506 Housing... the recipient, must it submit its monitoring evaluation/results to the Indian tribe? Yes. The Indian tribe as the grant beneficiary must receive a copy of the monitoring evaluation/results so that it can...

  1. Peer review comments on drug trials submitted to medical journals differ depending on sponsorship, results and acceptance: a retrospective cohort study

    NARCIS (Netherlands)

    Lent, M. van; Hout, J. in't; Out, H.J.

    2015-01-01

    OBJECTIVE: During peer review, submitted manuscripts are scrutinised by independent experts to assist journal editors in their decision-making and to help improve the quality of articles. In this retrospective cohort study, peer review comments for drug trials submitted to medical journals were

  2. Moxidectin residues in tissues of lambs submitted to three endoparasite control programs.

    Science.gov (United States)

    Fernandes, Maria Angela Machado; Gilaverte, Susana; Bianchi, Michele Dell; da Silva, Claudio José Araujo; Molento, Marcelo Beltrão; Reyes, Felix Guillermo Reyes; Monteiro, Alda Lucia Gomes

    2017-10-01

    The indiscriminate and continuous use of anthelmintic drugs has promoted the selection of resistant parasites population, the presence of drug residues in food products, and heavy environmental contamination. The aim of the present study was to determine the presence of antiparasitic drug residues in 42-days old lamb serum and tissues, submitted to three endoparasite control programs: preventive treatment (PT) using moxidectin (MOX) at every 28days; selective treatment (FEC) using MOX when fecal egg count was greater than or equal to 700; and selective treatment (FMC), using MOX when FAMACHA/FMC score was 3 and above. For this purpose, MOX residues were quantified in serum, muscle, fat, liver and kidney. Lambs were slaughtered when reaching 30kg of body weight, and after a 28-day MOX withdrawal period. Before slaughter, blood was collected to determine the concentration of MOX in serum. Tissues and organ samples were collected at slaughter. The quantitation of MOX residues was performed using liquid chromatography tandem mass spectrometry (LC-MS/MS). From the 756 tissue samples analyzed, only one sample of fat from the PT group showed residue levels (586.3μg/kg) above the maximum residue limit (MRL) of 500μg/kg. No treated lambs presented traces of MOX residues in fat and liver, suggesting possible environmental contamination. In conclusion, all weaned lambs, produced in continuous grazing and subjected to gastrointestinal parasite control programs via selective (FEC and FMC) or preventive (PT) treatment, displayed a low risk (<1%) of MOX residues above the MRL in muscle, fat, kidney, and liver. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Geochemical and Mineralogical Changes in Compacted MX-80 Bentonite Submitted to Heat and Water Gradients

    Energy Technology Data Exchange (ETDEWEB)

    Gomez-Espina, R.; Villar, M. V.

    2010-05-01

    A 20-cm high column of MX80 bentonite compacted at dry density 1.70 g/cm{sup 3} with an initial water content of 16 percent was submitted to heating and hydration by opposite ends for 496 days (TH test). The temperature at the bottom of the column was set at 140 degree centigrade and on top at 30 degree centigrade, and deionised water was injected on top at a pressure of 0.01 MPa. Upon dismantling water content, dry density, mineralogy, specific surface area, cation exchange capacity, content of exchangeable cations, and concentration of soluble salts and pH of aqueous extracts were determined in different positions along the bentonite column. The pore water composition was modelled with a geochemical software. The test tried to simulate the conditions of an engineered barrier in a deep geological repository for high-level radioactive waste. The water intake and distribution of water content and dry density along the bentonite were conditioned by the thermal gradient. Liquid water did not penetrate into the column beyond the area in which the temperature was higher than 100 degree centigrade. A convection cell was formed above this area, and liquid water loaded with ions evaporated towards cooler bentonite as it reached the area where the temperature was too high. In this area precipitation of mineral phases took place, Advection, interlayer exchange and dissolution/precipitation processes conditioned the composition of the pore water along the column. In most of the column the pore water was Na-SO{sub 4} {sup 2}- type, and changed to Na-Cl near the heater. TH treatment did not cause significant changes in the smectite content or the other mineral phases of the bentonite. (Author) 41 refs.

  4. Buccal cells submitted to three different storage conditions before DNA extraction

    Directory of Open Access Journals (Sweden)

    Fernanda Nedel

    2009-04-01

    Full Text Available This study evaluated quantitatively and qualitatively the effect of the storage time of samples before the application of the cell lysis solution (CLS for extracting DNA from buccal cells (BC. BC from the upper and lower gutter region were collected from 5 volunteers using special cytobrushes (Gentra, totaling 3 collections for each individual. In the control group (n=10, CLS was applied soon after BC collection. In the other two groups, samples were stored at room temperature (n=10 or at 4°C (n=10. After CLS application, DNA was extracted according to the manufacturer's instructions (Puregene DNA Buccal Cell Kit; Gentra Systems, Inc.. The DNA obtained was evaluated by two calibrated blind examiners using spectrophotometry and analysis of DNA bands (0.8% agarose gel electrophoresis. The obtained data were submitted to one-way ANOVA. The means and standard deviations for DNA extracted under immediate, room temperature and cooling temperature conditions were 3.5 ± 0.7, 3.0 ± 0.6 and 4.1 ± 1.8 µg, respectively (p=0.385. No significant differences were found in relation to the amount of DNA for the different storage conditions. However, in the visual analysis of the DNA bands, no trace of DNA degradation was detected when CSL was applied soon after DNA collection, while DNA bands with degradation could be observed in the other groups. Within the limitations of the study, it may be concluded that CLS should be applied soon after DNA collection in order to obtain high-quality DNA from BC.

  5. Content of reserves, vegetative vigor and yield of grapevines submitted to two harvests per vegetative cycle

    Directory of Open Access Journals (Sweden)

    Anzanello Rafael

    2015-04-01

    Full Text Available This study evaluated the content of reserves in the branches and assessed the vegetative vigor and yield of Niagara Branca, Niagara Rosada and Concord grapevines submitted to two harvests per vegetative cycle. The plants were subjected to a winter pruning (WP performed by means of a short pruning, and to a green pruning (GP at the end of spring performed by pruning branches from the fourth bud above the last grape cluster. The treatments included Control 1 (WP on 07-20-07/no GP, Control 2 (WP on 0-22-07/no GP, T1 (WP on 07-20-07/GP on 11-15-07, T2 (WP on 07-20-07/GP on 12-17- 07, T3 (WP on 08-22-07/GP on 11-15-07 and T4 (WP on 08-22-07/GP on 12-17-07. The variables evaluated included grapevine production for the two crops, the leaf area index (LAI throughout the vegetative cycle, and the content of reserves in the branches in the following stages: 2007 WP, first crop flowering, GP on 11-15-07, GP on 12-17-07, post-harvest of first and second crop, and 2008 WP. The WP associated to GP allowed to obtain two harvests in all cultivars being more effective in the T3. The shoots emitted by GP caused changes in the LAI and affected the dynamic of synthesis/ consumption of reserves in the branches of the grapevines. In plants with GP, there was reduction in the content of reserves at the end of the crop cycle compared to control plants. The pruning management to obtain two annual crops increased the annual production, but reduced the level of reserves of the grapevines.

  6. Publication outcome of abstracts submitted to the American Academy of Ophthalmology meeting.

    Science.gov (United States)

    Mimouni, Michael; Krauthammer, Mark; Abualhasan, Hamza; Badarni, Hanan; Imtanis, Kamal; Allon, Gilad; Berkovitz, Liron; Blumenthal, Eytan Z; Mimouni, Francis B; Amarilyo, Gil

    2018-01-01

    Abstracts submitted to meetings are subject to less rigorous peer review than full-text manuscripts. This study aimed to explore the publication outcome of abstracts presented at the American Academy of Ophthalmology (AAO) annual meeting. Abstracts presented at the 2008 AAO meeting were analyzed. Each presented abstract was sought via PubMed to identify if it had been published as a full-text manuscript. The publication outcome, journal impact factor (IF), and time to publication were recorded. A total of 690 abstracts were reviewed, of which 39.1% were subsequently published. They were published in journals with a median IF of 2.9 (range 0-7.2) and a median publication time of 426 days (range 0-2,133 days). A quarter were published in the journal Ophthalmology, with a shorter time to publication (median 282 vs. 534 days, p =0.003). Oral presentations were more likely to be published than poster presentations (57.8% vs. 35.9%, p <0.001) and in journals with higher IFs (3.2 vs. 2.8, p =0.02). Abstracts describing rare diseases had higher publication rates (49.4% vs. 38.0%, p =0.04) and were published in higher IF journals (3.7 vs. 2.9, p =0.03), within a shorter period of time (358 vs. 428 days, p =0.03). In multivariate analysis, affiliation with an institute located in the United States ( p =0.002), abstracts describing rare diseases ( p =0.03), and funded studies ( p =0.03) were associated with publication in higher IF journals. Almost 40% of abstracts were published. Factors that correlated with publication in journals with higher IF were a focus on rare diseases, affiliation with a US institute, and funding.

  7. Characterization of Conventional and High-Translucency Y-TZP Dental Ceramics Submitted to Air Abrasion.

    Science.gov (United States)

    Tostes, Bhenya Ottoni; Guimarães, Renato Bastos; Noronha-Filho, Jaime Dutra; Botelho, Glauco Dos Santos; Guimarães, José Guilherme Antunes; Silva, Eduardo Moreira da

    2017-01-01

    This study evaluated the effect of air-abrasion on t®m phase transformation, roughness, topography and the elemental composition of three Y-TZP (Yttria-stabilized tetragonal zirconia polycrystal) dental ceramics: two conventional (Lava Frame and IPS ZirCad) and one with high-translucency (Lava Plus). Plates obtained from sintered blocks of each ceramic were divided into four groups: AS (as-sintered); 30 (air-abrasion with 30 mm Si-coated Al2O3 particles); 50 (air-abrasion with 50 mm Al2O3 particles) and 150 (air-abrasion with 150 mm Al2O3 particles). After the treatments, the plates were submitted to X-ray diffractometry; 3-D profilometry and SEM/EDS. The AS surfaces were composed of Zr and t phases. All treatments produced t®m phase transformation in the ceramics. The diameter of air-abrasion particles influenced the roughness (150>50>30>AS) and the topography. SEM analysis showed that the three treatments produced groove-shaped microretentions on the ceramic surfaces, which increased with the diameter of air-abrasion particles. EDS showed a decrease in Zr content along with the emergence of O and Al elements after air-abrasion. Presence of Si was also detected on the plates air-abraded with 30 mm Si-coated Al2O3 particles. It was concluded that irrespective of the type and diameter of the particles, air-abrasion produced t®m phase transformation, increased the roughness and changed the elemental composition of the three Y-TZP dental ceramics. Lava Plus also behaved similarly to the conventional Y-TZP ceramics, indicating that this high translucency ceramic could be more suitable to build monolithic ceramic restorations in the aesthetic restorative dentistry field.

  8. Properties of dental resins submitted to pH catalysed hydrolysis.

    Science.gov (United States)

    Cilli, Renato; Pereira, Jose Carlos; Prakki, Anuradha

    2012-12-01

    This study evaluated the surface microhardness (SM) and roughness (SR) alterations of dental resins submitted to pH catalysed degradation regimens. Thirty discs of each TPH Spectrum (Dentsply), Z100 (3M-ESPE), or an unfilled experimental bis-GMA/TEGDMA resin were fabricated, totaling 90 specimens. Each specimen was polymerized for 40 s, finished, polished, and individually stored in deionized water at 37 °C for 7 days. Specimens were randomly assigned to the following pH solutions: 1.0, 6.9 or 13, and for SM or SR evaluations (n = 5). Baseline Knoop-hardness of each specimen was obtained by the arithmetic mean of five random micro-indentations. For SR, mean baseline values were obtained by five random surface tracings (R(a)). Specimens were then soaked in one of the following storage media at 37 °C: (1) 0.1 M, pH 1.0 HCl, (2) 0.1 N, pH 13.0 NaOCl, and (3) deionized water (pH 6.9). Solutions were replaced daily. Repeated SM and SR measurements were performed at the 3-, 7- and 14-day storage time intervals. For each test and resin, data were analysed by two-way ANOVA followed by Tukey's test (α = 0.05). There was significant decrease in SM and increase in SR values of composites after storage in alkaline medium. TPH and Z100 presented similar behaviour for SM and SR after immersion in the different media, whereas unfilled resin values showed no significant change. Hydrolytic degradation of resin composites seems to begin with the silanized inorganic particles and therefore depend on their composition. To accelerate composite hydrolysis and produce quick in vitro microstructural damage, alkaline medium appears to be more suitable than acidic medium. Contemporary resin composite properties seem to withstand neutral and acidic oral environments tolerably well. Copyright © 2012 Elsevier Ltd. All rights reserved.

  9. THE ACTION OF AVOCADO OIL ON THE LIPIDOGRAM OF WISTAR RATS SUBMITTED TO PROLONGED ANDROGENIC STIMULUM.

    Science.gov (United States)

    de Souza Abboud, Renato; Alves Pereira, Vivian; Soares da Costa, Carlos Alberto; Teles Boaventura, Gilson; Alves Chagas, Mauricio

    2015-08-01

    the abuse of steroid hormones administered in chronic form may cause alterations in the lypidic profile, conveying na increase in the levels of LDL, and reduction in the levels of HDL. In average, 53.44% of the lypidic composition of the avocado core is composed of oleic acid (which is a phytosterol) and the study of the hypolipemiating effect of these substances has been performed aiming at the prevention and control of dislypidemias. to assess the potential hypolipemiant power of the avocado oil on the lypidogram of adult male Wistar rats submitted to prolonged androgenic hiperestimulation. twenty eight Wistar rats were divided in 4 groups of 7 animals: the control group (CG); Avocado Oil Group (AOG) fed with a staple based on Avocado Oil; Induced Grupo (IG); and the Induced Grupo fed with a staple based on Avocado Oil (AOIG). The inducing was performed through surgery to subcutaneously implant sillicon pellets suffed with 1 ml of testosterone propionate which were replaced at every 4 weeks. VLDL (AOIG: 28.14 ± 4.45; IG:36.83 ± 5.56 mg/ml); Triglicerides (AOIG: 140.07 ± 22.66; IG: 187.2 ± 27 mg/ml); HDL (AOIG: 40, 67 ± 1.2; GI: 35.09 ± 0.8; AOG: 32.31 ± 2.61 e CG: 32.36 ± 4.93 mg/ml) Testosterone (AOIG:1.42 ± 0.46; GI: 2.14 ± 0.88; AOG: 2.97 ± 1.34 e CG:1.86 ± 0.79 ng/ml). avocado Oil exerted a direct regulating effect on the lypidic profile, acting efficiently on animals submmited to androgenic stimulation through a prolonged period. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  10. "Metabolism of Odontoblast-like cells submitted to transdentinal irradiation with blue and red LED".

    Science.gov (United States)

    Almeida, Leopoldina de Fátima Dantas de; Basso, Fernanda Gonçalves; Turrioni, Ana Paula Silveira; de-Souza-Costa, Carlos Alberto; Hebling, Josimeri

    2017-11-01

    The present study evaluated the trans-dentinal effect of light emitting diodes (LEDs) irradiation on the metabolism of odontoblast-like cells. Seventy-two dentin discs (0.2mm thick) were obtained from human molar teeth. MDPC-23 cells (20,000 cells/disc) were seeded on the pulpal side of the discs using DMEM, supplemented with 10% fetal bovine serum (FBS). After 12h, the culture medium was replaced with DMEM containing 0.5% FBS. After additional 12h, blue (455±10nm) or red (630±10nm) LEDs were used at irradiances of 80 and 40mW/cm(2), respectively, to irradiate the occlusal side of the discs. The energy doses were fixed at 2 or 4J/cm(2). Cell viability, alkaline phosphatase activity (ALP), total protein production and collagen synthesis were evaluated 72h after irradiation. Data were submitted to Kruskal-Wallis and Mann-Whitney tests (α=0.05). Red light promoted proliferative effects at the energy dose of 4J/cm(2). Conversely, cell cultures irradiated with 2J/cm(2) emitted by the blue light showed reduced viability. ALP production was stimulated by red light in comparison with blue light at 4J/cm(2). Total protein production was reduced after exposure to blue light at 4J/cm(2), while no effect was observed on collagen production. Irradiation with red LED at 4J/cm(2) bio-stimulated the viability of odontoblast-like cells, whilst blue light had unfavorable effects on the cellular metabolism. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Effect of maternal exercise on biochemical parameters in rats submitted to neonatal hypoxia-ischemia.

    Science.gov (United States)

    Marcelino, Thiago Beltram; de Lemos Rodrigues, Patrícia Idalina; Miguel, Patrícia Maidana; Netto, Carlos Alexandre; Pereira Silva, Lenir Orlandi; Matté, Cristiane

    2015-10-05

    Pregnancy is a critical period for brain metabolic programming, being affected by individual environment, such as nutrition, stress, and physical exercise. In this context, we previously reported a cerebral antioxidant upregulation and mitochondrial biogenesis in the offspring delivered from exercised mothers, which could provide neuroprotection against neonatal insults. Hypoxia-ischemia (HI) encephalopathy is one of the most studied models of neonatal brain injury; disrupting motor, cognitive, and learning abilities. Physiopathology includes oxidative stress, allied to mitochondria energy production failure, glutamatergic excitotoxicity, and cell death. In this study we evaluated the effect of maternal swimming during pregnancy on offspring׳s brain oxidative status evaluated fourteen days after HI stablishment. Swimming exercise was performed by female adult rats one week before and during pregnancy, in controlled environment. Their offspring was submitted to HI on postnatal day 7, and the brain samples for biochemical assays were obtained in the weaning. Contrary to our expectations, maternal exercise did not prevent the oxidative alterations observed in brain from HI-rats. In a general way, we found a positive modulation in the activities of antioxidant enzymes, measured two weeks after HI, in hippocampus, striatum, and cerebellum of pups delivered from exercised mothers. Reactive species levels were modulated differently in each structure evaluated. Considering the scenery presented, we concluded that HI elicited a neurometabolic adaptation in both brain hemispheres, particularly in hippocampus, parietal cortex, and cerebellum; while striatum appears to be most damaged. The protocol of aerobic maternal exercise was not enough to fully prevent HI-induced brain damages. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. Study of surface alterations of composite and ionomeric materials submitted to simulation of a high cariogenic challenge

    Directory of Open Access Journals (Sweden)

    VIEIRA Alexandre Rezende

    1999-01-01

    Full Text Available We evaluated the surface of composite resins and glass-ionomer cements in a situation of high cariogenic challenge. Based on seventy-five standard test specimens of one glass-ionomer cement (Chelon Fil - ESPE, one resin-modified glass-ionomer (Vitremer - 3M, two polyacid-modified composite (VariGlass and Dyract - Dentsply and one composite resin (Heliomolar - Vivadent, submitted to fourteen days of demineralization and remineralization cycling to simulate a high cariogenic challenge, the erosive aspects of the surface of the materials were assessed. All of the samples were evaluated by scanning electronic microscope and compared with another five test specimens of each material, prepared in the same way and serving as control. All of the materials studied suffered erosive action by the media, with different characteristics due to the different compositions, after being submitted to in vitro simulation of a high cariogenic challenge.

  13. Validation of an educative manual for patients with head and neck cancer submitted to radiation therapy 1

    Science.gov (United States)

    da Cruz, Flávia Oliveira de Almeida Marques; Ferreira, Elaine Barros; Vasques, Christiane Inocêncio; da Mata, Luciana Regina Ferreira; dos Reis, Paula Elaine Diniz

    2016-01-01

    Abstract Objective: develop the content and face validation of an educative manual for patients with head and neck cancer submitted to radiation therapy. Method: descriptive methodological research. The Theory of Psychometrics was used for the validation process, developed by 15 experts in the theme area of the educative manual and by two language and publicity professionals. A minimum agreement level of 80% was considered to guarantee the validity of the material. Results: the items addressed in the assessment tool of the educative manual were divided in three blocks: objectives, structure and format, and relevance. Only one item, related to the sociocultural level of the target public, obtained an agreement rate manual proposed were attended to. This can contribute to the understanding of the therapeutic process the head and neck cancer patient is submitted to during the radiation therapy, besides supporting clinical practice through the nursing consultation. PMID:27305178

  14. Resulting alterations at the level of testes and semen in dogs submitted to vincristine sulphate administra tion

    OpenAIRE

    Carlos Roberto Daleck; Paulo Henrique Franceschini; João Guilherme Padilha Filho; Antonio Carlos Alessi; Joaquim Mansano Garcia; Maria Izabel Mello Martins; João Moreira da Costa Neto

    1995-01-01

    Sperm analysis and testicular histological studies were performed before and after vincristine sulphate treatment, in fourteen male dogs. In group I (n = 8), unilateral orchiectomy was carried out before and after mitostatic treatment, and testicular and epididymal biopsies were examined histologically. All histological examinations showed a slight to moderate degeneration of testicular tissue. In group II (n = 6) semen was collected and was submitted to laboratorial analysis. After vincristi...

  15. Physicochemical characteristics and sensory profile of honey samples from stingless bees (Apidae: Meliponinae) submitted to a dehumidification process.

    Science.gov (United States)

    Carvalho, Carlos A L; Sodré, Geni S; Fonseca, Antonio A O; Alves, Rogério M O; Souza, Bruno A; Clarton, Lana

    2009-03-01

    This study was conducted to evaluate the effect of a dehumidification process on the physicochemical and sensory characteristics of stingless-bee honey. Melipona scutellaris and M. quadrifasciata honey samples were submitted to a dehumidification process and to physicochemical (reducing sugars, apparent sucrose, moisture, diastatic activity, hydroxymethylfurfural, ash, pH, acidity, and electric conductivity) and sensory evaluations (fluidity, color, aroma, crystallization,flavor,and acceptability). The results indicated that the dehumidification process does not interfere with honey quality and acceptability.

  16. Maximum entropy, fractal dimension and lacunarity in quantification of cellular rejection in myocardial biopsy of patients submitted to heart transplantation

    Energy Technology Data Exchange (ETDEWEB)

    Neves, L A [Universidade Estadual Paulista, IGCE, DEMAC, Rio Claro, SP (Brazil); Oliveira, F R; Peres, F A [Faculdade de Tecnologia de Sao Jose do Rio Preto, Sao Jose do Rio Preto, SP (Brazil); Moreira, R D; Moriel, A R; De Godoy, M F [Faculdade de Medicina de Sao Jose do Rio Preto, FAMERP, Sao Jose do Rio Preto, SP (Brazil); Murta Junior, L O, E-mail: laneves@rc.unesp.br [Universidade de Sao Paulo, FFCLRP, Depto Computacao e Matematica, Ribeirao Preto (Brazil)

    2011-03-01

    This paper presents a method for the quantification of cellular rejection in endomyocardial biopsies of patients submitted to heart transplant. The model is based on automatic multilevel thresholding, which employs histogram quantification techniques, histogram slope percentage analysis and the calculation of maximum entropy. The structures were quantified with the aid of the multi-scale fractal dimension and lacunarity for the identification of behavior patterns in myocardial cellular rejection in order to determine the most adequate treatment for each case.

  17. Chemical and morphological characterization of sugarcane bagasse submitted to a delignification process for enhanced enzymatic digestibility

    Directory of Open Access Journals (Sweden)

    Rezende Camila

    2011-11-01

    Full Text Available Abstract Background In recent years, biorefining of lignocellulosic biomass to produce multi-products such as ethanol and other biomaterials has become a dynamic research area. Pretreatment technologies that fractionate sugarcane bagasse are essential for the successful use of this feedstock in ethanol production. In this paper, we investigate modifications in the morphology and chemical composition of sugarcane bagasse submitted to a two-step treatment, using diluted acid followed by a delignification process with increasing sodium hydroxide concentrations. Detailed chemical and morphological characterization of the samples after each pretreatment condition, studied by high performance liquid chromatography, solid-state nuclear magnetic resonance, diffuse reflectance Fourier transformed infrared spectroscopy and scanning electron microscopy, is reported, together with sample crystallinity and enzymatic digestibility. Results Chemical composition analysis performed on samples obtained after different pretreatment conditions showed that up to 96% and 85% of hemicellulose and lignin fractions, respectively, were removed by this two-step method when sodium hydroxide concentrations of 1% (m/v or higher were used. The efficient lignin removal resulted in an enhanced hydrolysis yield reaching values around 100%. Considering the cellulose loss due to the pretreatment (maximum of 30%, depending on the process, the total cellulose conversion increases significantly from 22.0% (value for the untreated bagasse to 72.4%. The delignification process, with consequent increase in the cellulose to lignin ratio, is also clearly observed by nuclear magnetic resonance and diffuse reflectance Fourier transformed infrared spectroscopy experiments. We also demonstrated that the morphological changes contributing to this remarkable improvement occur as a consequence of lignin removal from the sample. Bagasse unstructuring is favored by the loss of cohesion between

  18. Molecular mass distribution and epitopes of the beta lactoglobulin submitted to hydrolysis pre-transglutaminase treatment

    Energy Technology Data Exchange (ETDEWEB)

    Villas-Boas, M.B.; Zollner, R.L.; Netto, F.M. [Universidade Estadual de Campinas (UNICAMP), SP (Brazil); Paes Leme, A.F. [Laboratorio Nacional de Luz Sincrotron (LNLS), Campinas, SP (Brazil); Benede, S.; Molina, E. [Universidad Autonoma de Madrid (Spain)

    2012-07-01

    Full text: The {beta}-Lactoglobulin ({beta}-Lg) is a whey protein with important nutritional proper ties but very resistant to pepsin digestion and consequently highly antigenic. This protein can be modified by transglutaminase (TG) although it is required a pretreatment to increase their susceptibility to the TG action. In the present study the hydrolysis pre-TG treatment was used to improve the TG accessibility on {beta}-Lg and the MM distribution and antigenic fragments were evaluated. For pre-TG treatment, the {beta}-Lg (Davisco Inc.) was hydrolyzed with bromelain (3% of {beta}-Lg w/w in distilled water; 25 U enzyme g{sup 1} of substrate, pH 7.5, 240 min) and then polymerized by TG (7% hydrolysate, 10U TG g{sup 1} protein, 50 C/180 min). The samples were evaluated by SDS-PAGE/tricine and by RP-nanoUPLC (nanoAcquity UPLC, Waters) coupled with nano-electrospray tandem mass spectrometry on a Q-Tof Ultima API mass spectrometer (MicroMass/Waters) at LNBio. The products were also submitted to pepsin digestion and the peptide identification was performed by RP-HPLC-tandem mass spectrometry (RP-HPLC-MS/MS, Brucker) with support from CIAL. The {beta}-Lg hydrolysed by bromelain and polymerized by TG had a broad MM distribution. The intact mass analysis indicated that the non modified {beta}Lg -A showed 18.362 Da and the non modified {beta}Lg -B 18.274 Da, which is in agreement with the theoretical corresponding masses. The use of bromelain pre-TG treatment resulted in polymers with MM from 61.052 to 67.654 Da, although some non modified protein was still present. In addition, the non modified {beta}-Lg showed fragments that present high antigenicity (such as Leu{sub 95} - Leu{sub 104}, Asp{sub 95} - Phe{sub 105}, Tyr{sub 42} - Leu{sub 54}, lle{sub 29} - Val{sub 41}), previously identified as IgE-binding epitopes. After hydrolysis following by TG treatment the fragment Tyr{sub 42} - Leu{sub 54} was still present, however the other fragments that were observed in the non

  19. 71 FR 2900 - Notice of Public Information Collection Requirements Submitted to OMB for Review

    Science.gov (United States)

    2006-01-18

    ...U.S. Agency for International Development (USAID) has submitted the following information collections to OMB for review and clearance under the Paperwork Reduction Act of 1995, Public Law 104-13. Comments regarding this information collection are best assured of having their full effect if received within 30 days of this notification. Comments should be sent via email to David-- [email protected] or fax to 202-395-7285. Copies of submission may be obtained by calling (202) 712-1365. Supplementary Information: OMB Number: OMB 0412-NEW. Form Number: N/A. Title: Minority Serving Institution Database. Type of Submission: New Information Collection. Purpose: The U.S. Agency for International Development (USAID) requests comment on its proposal to expand its existing automated Extranet database to include voluntary registration of U.S. Minority Serving Institutions (MSIs). The existing application, the Small Business Resource Database (SBRD) was placed into production at the beginning of Fiscal Year 2004. Small and Small and Disadvantaged Business interested in pursuing contracts with USAID may register with the Agency on a voluntary basis. These data are then made available via a secure Extranet conduit to Agency Program, Technical and Contact Officers worldwide. The Agency experienced a significant improvement in the amount of contracting with these entities in Fiscal Year 2004, versus USAID's performance in 2003, and in comparison to the averages for the Executive Branch of the Federal government. The Agency's performance in this regard is published at the following URL: http:// www.sba.gov/GC/goals/Goaling-Report-08-21-2005.pdf. USAID proposes to capture the voluntary registration of Minority Serving Institutions (MSIs), who may be interested in pursuing grants with USAID in furtherance of the Agency's international development initiatives. The existing SBRD application, and the Extranet conduit for disseminating these data within USAID would be utilized for this

  20. Validation of an educative manual for patients with head and neck cancer submitted to radiation therapy.

    Science.gov (United States)

    Cruz, Flávia Oliveira de Almeida Marques da; Ferreira, Elaine Barros; Vasques, Christiane Inocêncio; Mata, Luciana Regina Ferreira da; Reis, Paula Elaine Diniz Dos

    2016-06-14

    develop the content and face validation of an educative manual for patients with head and neck cancer submitted to radiation therapy. descriptive methodological research. The Theory of Psychometrics was used for the validation process, developed by 15 experts in the theme area of the educative manual and by two language and publicity professionals. A minimum agreement level of 80% was considered to guarantee the validity of the material. the items addressed in the assessment tool of the educative manual were divided in three blocks: objectives, structure and format, and relevance. Only one item, related to the sociocultural level of the target public, obtained an agreement rate publicidade. Foi considerado o índice de concordância de, no mínimo, 80% para se garantir a validação do material. os itens abordados no instrumento de avaliação do manual educativo foram divididos em três blocos: objetivos, estrutura e apresentação, e relevância. Apenas um item, relacionado ao nível sociocultural do público-alvo, obteve índice de concordância publicidad. Fue considerado un índice de concordancia que fuese, por lo menos, de 80%, para garantizar la validación del material. los ítems abordados en el instrumento de evaluación del manual educativo fueron divididos en tres bloques: objetivos, estructura y presentación, y relevancia. Apenas un ítem, relacionado al nivel sociocultural del público-objetivo, obtuvo un índice de concordancia <80%, habiendo sido reformulado con base en las sugestiones de los participantes. Todos los otros ítems fueron considerados adecuados y/o totalmente adecuados en los tres bloques propuestos: objetivos (92,38%), estructura y presentación (89,74%), y relevancia (94,44%). el manual educativo propuesto fue considerado válido en lo que se refiere al contenido y a la apariencia. Se sugiere que puede contribuir para la comprensión del proceso terapéutico, al cual el paciente con cáncer de cabeza y cuello es sometido al

  1. EFFECT OF SIZE OF INTESTINAL DIVERSIONS IN OBESE PATIENTS WITH METABOLIC SYNDROME SUBMITTED TO GASTRIC BYPASS.

    Science.gov (United States)

    Ramos, Rafael Jacques; Mottin, Cláudio Corá; Alves, Letícia Biscaino; Benzano, Daniela; Padoin, Alexandre Vontobel

    There is no consensus on the ideal size of intestinal loops in gastric bypass of bariatric surgeries. To evaluate the metabolic outcome of patients submitted to gastric bypass with alimentary and biliopancreatic loops of different sizes. Was conducted a retrospective cohort study in diabetic obese patients (BMI≥35 kg/m2) with metabolic syndrome submitted to gastric bypass. The patients were divided into three groups according to the size of the intestinal loop: group 1, biliopancreatic limb 50 cm length and alimentary limb 100 cm length; group 2 , biliopancreatic limb 50 cm length and alimentary limb 150 cm length; and group 3, biliopancreatic limb 100 cm length and alimentary limb 150 cm length. The effect of gastric bypass with different sizes of intestinal loops in relation to the parameters that define metabolic syndrome was determined. Sixty-three patients were evaluated, and they had a mean age of 44.7±9.4 years. All were diabetics, with 62 (98.4%) being hypertensive and 51 (82.2%) dyslipidemic. The three groups were homogeneous in relation to the variables. In 24 months, there was a remission of systemic arterial hypertension in 65% of patients in group 1, 62.5% in group 2 and 68.4% in group 3. Remission of diabetes occurred in 85% of patients in group 1, 83% in group 2 and 84% in group 3. There was no statistical difference in %LEW between the groups, and waist measurements decreased in a homogeneous way in all groups. The size of loops also had no influence on the improvement in dyslipidemia. Variation in size of intestinal loops does not appear to influence improvement in metabolic syndrome in this group of patients. Não há consenso sobre o tamanho ideal das alças intestinais no bypass gástrico em Y-de-Roux em cirurgias bariátricas. Avaliar os desfechos metabólicos de pacientes submetidos ao bypass gástrico com alça intestinal alimentar e biliopancreática de tamanhos diferentes. Realizou-se coorte retrospectiva em pacientes obesos (IMC≥35 kg

  2. Torque undergone by assemblies of single-domain magnetic nanoparticles submitted to a rotating magnetic field

    Science.gov (United States)

    Carrey, J.; Hallali, N.

    2016-11-01

    In the last 10 years, it has been shown in various types of experiments that it is possible to induce biological effects in cells using the torque generated by magnetic nanoparticles submitted to an alternating or a rotating magnetic field. In biological systems, particles are generally found under the form of assemblies because they accumulate at the cell membrane, are internalized inside lysosomes, or are synthesized under the form of beads containing several particles. The torque undergone by assemblies of single-domain magnetic nanoparticles has not been addressed theoretically so far and is the subject of the present article. The results shown in the present article have been obtained using kinetic Monte Carlo simulations, in which thermal activation is taken into account, so the torque undergone by ferromagnetic and superparamagnetic nanoparticles could both be simulated. The first system under study is a single ferromagnetic particle with its easy axis in the plane of the rotating magnetic field. Then, elements adding complexity to the problem are introduced progressively and the properties of the resulting system presented and analyzed: random anisotropy axes, thermal activation, assemblies, and finally magnetic interactions. The most complex studied systems are particularly relevant for applications and are assemblies of interacting superparamagnetic nanoparticles with randomly oriented anisotropy axes. Whenever it is possible, analytical equations describing the torque properties are provided, as well as their domain of validity. Although the properties of an assembly naturally derive from those of single particles, it is shown here that several of them were unexpected and are particularly interesting with regard to the maximization of torque amplitude in biological applications. In particular, it is shown that, in a given range of parameters, the torque of an assembly increases dramatically in the direction perpendicular to the plane of the rotating

  3. Clostridium difficile infection in Chilean patients submitted to hematopoietic stem cell transplantation

    Directory of Open Access Journals (Sweden)

    Javier Pilcante

    2015-12-01

    Full Text Available ABSTRACT Introduction: Patients submitted to hematopoietic stem cell transplantation have an increased risk of Clostridium difficile infection and multiple risk factors have been identi- fied. Published reports have indicated an incidence from 9% to 30% of transplant patients however to date there is no information about infection in these patients in Chile. Methods: A retrospective analysis was performed of patients who developed C. difficile infection after hematopoietic stem cell transplantations from 2000 to 2013. Statistical analysis used the Statistical Package for the Social Sciences software. Results: Two hundred and fifty patients were studied (mean age: 39 years; range: 17-69, with 147 (59% receiving allogeneic transplants and 103 (41% receiving autologous trans- plants. One hundred and ninety-two (77% patients had diarrhea, with 25 (10% cases of C. difficile infection being confirmed. Twenty infected patients had undergone allogeneic trans- plants, of which ten had acute lymphoblastic leukemia, three had acute myeloid leukemia and seven had other diseases (myelodysplastic syndrome, chronic myeloid leukemia, severe aplastic anemia. In the autologous transplant group, five patients had C. difficile infection; two had multiple myeloma, one had amyloidosis, one had acute myeloid leukemia and one had germinal carcinoma. The overall incidence of C. difficile infection was 4% within the first week, 6.4% in the first month and 10% in one year, with no difference in overall survival between infected and non-infected groups (72.0% vs. 67.6%, respectively; p-value = 0.56. Patients infected after allogeneic transplants had a slower time to neutrophil engraftment compared to non-infected patients (17.5 vs. 14.9 days, respectively; p-value = 0.008. In the autologous transplant group there was no significant difference in the neutrophil engraftment time between infected and non-infected patients (12.5 days vs. 11.8 days, respectively; p

  4. Proline content and protein patterns in Eucalyptus grandis shoots submitted to high and low temperature shocks

    Directory of Open Access Journals (Sweden)

    Gustavo M. Souza

    2004-07-01

    Full Text Available Proline content and protein patterns changes in response to temperature shocks of both acclimated and non acclimated E. grandis shoots cultivated in vitro were investigated. Analysis of soluble proteins through SDS-PAGE and proline were carried out after 12h at 12ºC (cold acclimation or 33ºC (heat acclimation, and immediately after temperature shocks at 41ºC and 0ºC. Analyses were also performed 24h after the temperature shocks (recovery period. Temperature treatment at 0ºC did not change soluble protein patterns both in acclimatized and non acclimatized plants, whereas cold temperature induced high proline levels, which kept relatively high after recovery period. Three novel, probably HSPs, proteins (90.5, 75 and 39 kDa were observed in both acclimated and non acclimated plants submitted to high temperatures. Plants exposed at 41ºC were able to recover from heat shocks after 24h, whereas they did not recover completely from cold shocks. The effect of the acclimation period on the recovering (homeostasis varied depending on the parameter evaluated, and type and duration of the temperature shock.As respostas às mudanças de temperatura de plantas aclimatadas e não aclimatadas de E. grandis cultivadas in vitro foram avaliadas considerando alterações dos níveis de prolina e proteínas solúveis totais. Análises de proteínas solúveis através de SDS-PAGE e prolina foram realizadas após 12h a 12ºC (aclimatação ao frio ou a 33ºC (aclimatação ao calor, e imediatamente depois dos choques térmicos a 41ºC e 0ºC. Análises também foram realizadas após um período de 24h depois dos choques térmicos (período de recuperação. O tratamento de temperatura a 0ºC não alterou o padrão de proteínas nas plantas aclimatadas e não aclimatadas, entretanto a temperatura baixa induziu altos níveis de prolina, que se mantiveram relativamente altos após o período de recuperação. Três novas proteínas (90,5, 75 e 39 kDa, provavelmente

  5. Resultados obtidos em mulheres portadoras de endometriose pélvica avançada e mulheres com ligadura tubária, submetidas a ICSI: análise comparativa Outcome of women with advanced pelvic endometriosis and women with tubal sterilization submitted to ICSI: a comparative analysis

    Directory of Open Access Journals (Sweden)

    Tsutomu Aoki

    2005-10-01

    exibem chances de implantação e gestação semelhantes àquelas do grupo TUB.PURPOSE: comparative analysis of the outcome of women with advanced pelvic endometriosis and women with tubal sterilization submitted to intracytoplasmic sperm injection (ICSI. METHODS: ninety-three infertile women, with normal menstrual cycle, without hormonal or surgical treatment during 12 months, body mass index of 20-25, ovaries with no tumors or cysts were included in the present study and divided into two groups: tubal sterilization (TUB, 39 women, and endometriosis (EDT, 54 women with III-EDT and IV-EDT, undergoing ovulatory induction using r-FSH and ICSI. Clinical and laboratorial data were compared. chi2, Fisher, Student's t, and Mann-Whitney tests were employed. RESULTS: lower estradiol levels (2,243.1 vs 1,666.3; p=0.001 and lower number of follicles per patient (16.9 vs 13.9, p=0.001 were noted in EDT group, in spite of more units of r-FSH (1,775.6 vs 1,998.6; p=0.007, for TUB and EDT, respectively. There were no differences in the rates of retrieved oocyte (69 vs 73.5%; p=0.071 as well as in normal fertilization rates (83.7 vs 81.7%; p=0.563, for TUB and EDT, respectively. However, lower number of top quality preembryos were obtained in patients from EDT group (36.5 vs 24.8%, TUB and EDT, respectively; p=0.005. Total pregnancy (41.0 vs 42.6%; p=0.950 and implantation rates (13.9 vs 14.5%; p=0.905 were not different when groups TUB and EDT were compared. CONCLUSIONS: ovaries of women from EDT group seem to be less responsive to ovulatory induction with r-FSH. EDT seems to impair the mean number of follicles and top quality preembryos with no impairment of retrieved oocyte and fertilization rates. However, once obtained, preembryos from EDT patients are able to exhibit similar implantation potential and pregnancy when compared with patients from TUB group.

  6. Causes of mortality of wild birds submitted to the Charles Darwin Research Station, Santa Cruz, Galapagos, Ecuador from 2002-2004.

    Science.gov (United States)

    Gottdenker, Nicole L; Walsh, Timothy; Jiménez-Uzcátegui, Gustavo; Betancourt, Franklin; Cruz, Marilyn; Soos, Catherine; Miller, R Eric; Parker, Patricia G

    2008-10-01

    Necropsy findings were reviewed from wild birds submitted to the Charles Darwin Research Station, Santa Cruz Island, Galápagos Archipelago between 2004 and 2006. One hundred and ninety cases from 27 different species were submitted, and 178 of these cases were evaluated grossly or histologically. Trauma and trauma-related deaths (n=141) dominated necropsy submissions. Infectious causes of avian mortality included myiasis due to Philornis sp. (n=6), avian pox (n=1), and schistosomosis (n=1).

  7. Culture results from milk samples submitted to veterinary diagnostic laboratories from August 2003 to December 2006 in New Zealand.

    Science.gov (United States)

    Petrovski, K R; Williamson, N B; Lopez-Villalobos, N; Parkinson, T J; Tucker, I G

    2011-11-01

    To determine the pattern of isolation of major mastitis-causing organisms isolated from milk samples submitted to five veterinary diagnostic laboratories in New Zealand. The culture results of 25,288 milk samples that were collected from dairy cows throughout New Zealand from August 2003 to December 2006 and submitted to a group of veterinary diagnostic laboratories were assembled, reviewed and summarised. Logistic regression was used to analyse the effect of year, region (i.e. North vs South Island), and season on the probability of isolating the two most common organisms. The most commonly isolated mastitis causing organisms from all samples were: Streptococcus uberis (23.6%), Staphylococcus aureus (23.5%), coagulase-negative staphylococci (CNS; 7.2%), Strep. dysgalactiae (6.2%), Bacillus spp. (4.0%), and coliforms (3.7%). The percentage of samples with isolates of Strep. uberis or Staph. aureus was affected by island, year and season (pculture of milk samples submitted to diagnostic laboratories in New Zealand, has changed significantly over the last 40 years, with a substantial increase in the percentage of isolates that are Strep. uberis and a decrease in isolates of Strep. agalactiae. There is a clear seasonal pattern to the isolation of both Strep. uberis and Staph. aureus, particularly the former. Knowledge of the aetiological agents causing bovine mastitis on a farm is of value in determining the choice of treatment. This dataset shows that, although there is seasonal pattern to the isolation of mastitis-causing organisms in New Zealand, both Strep. uberis and Staph. aureus are isolated throughout the year, so bacteriology is of value in determining aetiology even in late winter/early spring.

  8. Free-roaming and surrendered dogs and cats submitted to a humane shelter in Wellington , New Zealand , 1999--2006.

    Science.gov (United States)

    Rinzin, K; Stevenson, Ma; Probert, Dw; Bird, Rg; Jackson, R; French, Np; Weir, Ja

    2008-12-01

    To describe submissions of dogs and cats to an animal welfare shelter over a 6-year period, and to evaluate the association between the numbers of dogs and cats submitted per square kilometre, human population density, and standardised measures of socioeconomic deprivation. Details of free-roaming and surrendered dogs and cats presented to the Wellington shelter of the Society for the Prevention of Cruelty to Animals (SPCA) for the period 01 July 1999 to 28 February 2006 were recorded in a relational database. Data were plotted as counts of animals presented to the shelter each month as a function of calendar time. Kernel-smoothing techniques were used to describe the spatial distribution of capture location. The association between the number of dogs and cats submitted per square kilometre, human population density (both estimated at the mesh-block level), and mesh-block socioeconomic deprivation index were quantified using the Pearson product-moment correlation coefficient (r). The data comprised submission details for 3,709 dogs and 13,563 cats. There was a progressive decline in the number of dogs and cats submitted to the shelter over the study period, and a marked seasonal variation in submissions of cats. Submission density of dogs and cats was positively associated with human population density (Pearson's r=0.12; 95% CI=0.06-0.20 and 0.39; 95% CI=0.33-0.45, respectively) and socioeconomic deprivation (Pearson's r=0.12; 95% CI=0.05- 0.19 for both dogs and cats). Active approaches to free-roaming cat control by the Wellington SPCA should focus on the period June to September, prior to the feline breeding season, in population-dense and socioeconomically deprived areas. Composite analyses of submission details from all animal shelters in the Wellington region should allow factors associated with the distribution of free-roaming dogs and cats to be more precisely estimated.

  9. JOURNAL CLUB: Plagiarism in Manuscripts Submitted to the AJR: Development of an Optimal Screening Algorithm and Management Pathways.

    Science.gov (United States)

    Taylor, Donna B

    2017-04-01

    The objective of this study was to investigate the incidence of plagiarism in a sample of manuscripts submitted to the AJR using CrossCheck, develop an algorithm to identify significant plagiarism, and formulate management pathways. A sample of 110 of 1610 (6.8%) manuscripts submitted to AJR in 2014 in the categories of Original Research or Review were analyzed using CrossCheck and manual assessment. The overall similarity index (OSI), highest similarity score from a single source, whether duplication was from single or multiple origins, journal section, and presence or absence of referencing the source were recorded. The criteria outlined by the International Committee of Medical Journal Editors were the reference standard for identifying manuscripts containing plagiarism. Statistical analysis was used to develop a screening algorithm to maximize sensitivity and specificity for the detection of plagiarism. Criteria for defining the severity of plagiarism and management pathways based on the severity of the plagiarism were determined. Twelve manuscripts (10.9%) contained plagiarism. Nine had an OSI excluding quotations and references of less than 20%. In seven, the highest similarity score from a single source was less than 10%. The highest similarity score from a single source was the work of the same author or authors in nine. Common sections for duplication were the Materials and Methods, Discussion, and abstract. Referencing the original source was lacking in 11. Plagiarism was undetected at submission in five of these 12 articles; two had been accepted for publication. The most effective screening algorithm was to average the OSI including quotations and references and the highest similarity score from a single source and to submit manuscripts with an average value of more than 12% for further review. The current methods for detecting plagiarism are suboptimal. A new screening algorithm is proposed.

  10. Influence of finishing/polishing on color stability and surface roughness of composites submitted to accelerated artificial aging

    Directory of Open Access Journals (Sweden)

    Gustavo Da Col dos Santos Pinto

    2013-01-01

    Full Text Available Aim: To assess the influence of finishing/polishing procedure on color stability (ΔE and surface roughness (Ra of composites (Heliomolar and Tetric - color A2 submitted to accelerated artificial aging (AAA. Materials and Methods : Sixty test specimens were made of each composite (12 mm × 2 mm and separated into six groups (n = 10, according to the type of finishing/polishing to which they were submitted: C, control; F, tip 3195 F; FF, tip 3195 FF; FP, tip 3195 F + diamond paste; FFP, tip 3195 FF + diamond paste; SF, Sof-Lex discs. After polishing, controlled by an electromechanical system, initial color (spectrophotometer PCB 6807 BYK GARDNER and Ra (roughness meter Surfcorder SE 1700, cut-off 0.25 mm readings were taken. Next, the test specimens were submitted to the AAA procedure (C-UV Comexim for 384 hours, and at the end of this period, new color readings and R a were taken. Results: Statistical analysis [2-way analysis of variance (ANOVA, Bonferroni, P < 0.05] showed that all composites demonstrated ΔE alteration above the clinically acceptable limits, with the exception of Heliomolar composite in FP. The greatest ΔE alteration occurred for Tetric composite in SF (13.38 ± 2.10 statistically different from F and FF (P < 0.05. For Ra , Group F showed rougher samples than FF with statistically significant difference (P < 0.05. Conclusion: In spite of the surface differences, the different finishing/polishing procedures were not capable of providing color stability within the clinically acceptable limits.

  11. Growth analysis partitioning of assimilate in tomato plants cv. Micro-Tom submitted to nitrogen and pyraclostrobin

    Directory of Open Access Journals (Sweden)

    Emanuela Garbin Martinazzo

    2015-10-01

    Full Text Available This work aimed at comparing the growth and partitioning of assimilate in tomato plants cv. Micro-Tom subjected to nitrogen and pyraclostrobin. This substance favors the development of chloroplasts and the synthesis of chlorophyll. Tomato plants were submitted to the treatments: T1, complete nutrient solution without pyraclostrobin, T2, complete nutrient solution + pyraclostrobin, T3, ½ strength nutrient solution without N pyraclostrobin and T4, ½ strength nutrient solution N + pyraclostrobin. Plants were collected at regular intervals of seven days after transplantation throughout the crop cycle, with dry mass and leaf area being determined. From the primary data, growth analysis was carried out to calculate total dry matter (Wt, the instantaneous rates of dry matter production (Ct, relative growth (Rw e net assimilation (Ea, leaf area (Af, production rates (Ca and relative growth of leaf area index (Ra and leaf weight (Fw specific leaf area (Sa the dry matter partitioning between organs and number (Nfr and fresh fruit weight (Wfr. Plants of T1 showed higher Wt, Ct and Wfr compared to those of other treatments. However, the T2 plants exhibited similar Nfr to T1 plants, being superior to others. Also allocated on the total dry matter and at the end of the cycle, a higher percentage of dry matter in the seafood compared to T3 and T4 plants. Also they allocated relative to the total dry matter and at the end of the cycle, a higher percentage in fruits of plants to T3 and T4. The association between nitrogen and pyraclostrobin changes the growth and assimilated partition on tomato plants cv. Micro – Tom, and those submitted to ½ dose of nitrogen have a higher total dry matter and less final percentage of total dry matter in fruits , comparatively to those submitted to the association ½ dose of nitrogen and pyraclostrobin.

  12. Physiological response of invasive mussel Limnoperna fortunei (Dunker, 1857) (Bivalvia: Mytilidae) submitted to transport and experimental conditions.

    Science.gov (United States)

    Cordeiro, N I S; Andrade, J T M; Montresor, L C; Luz, D M R; Araújo, J M; Martinez, C B; Pinheiro, J; Vidigal, T H D A

    2017-03-01

    Successful animal rearing under laboratory conditions for commercial processes or laboratory experiments is a complex chain that includes several stressors (e.g., sampling and transport) and incurs, as a consequence, the reduction of natural animal conditions, economic losses and inconsistent and unreliable biological results. Since the invasion of the bivalve Limnoperna fortunei (Dunker, 1857) in South America, several studies have been performed to help control and manage this fouling pest in industrial plants that use raw water. Relatively little attention has been given to the laboratory rearing procedure of L. fortunei, its condition when exposed to a stressor or its acclimation into laboratory conditions. Considering this issue, the aims of this study are to (i) investigate L. fortunei physiological responses when submitted to the depuration process and subsequent air transport (without water/dry condition) at two temperatures, based on glycogen concentrations, and (ii) monitor the glycogen concentrations in different groups when maintained for 28 days under laboratory conditions. Based on the obtained results, depuration did not affect either of the groups when they were submitted to approximately eight hours of transport. The variation in glycogen concentration among the specimens that were obtained from the field under depurated and non-depurated conditions was significant only in the first week of laboratory growth for the non-depurated group and in the second week for the depurated group. In addition, the tested temperature did not affect either of the groups that were submitted to transport. The glycogen concentrations were similar to those of the specimens that were obtained from the field in third week, which suggests that the specimens acclimated to laboratory conditions during this period of time. Thus, the results indicate that the air transport and acclimation time can be successfully incorporated into experimental studies of L. fortunei. Finally

  13. LBNL 2011 Inter-Laboratory Comparison for Laboratories Submitting Specular Data to the International Glazings Database (IGDB)

    Energy Technology Data Exchange (ETDEWEB)

    Jonsson, Jacob C. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2012-08-01

    Laboratories that submit data to the International Glazings Database (IGDB) have to participate in an inter-laboratory comparison (ILC) every four years. This is a procedure that allow both contributors and database maintainers to confirm that the measurement capabilities of the laboratories are of high quality. All laminate and applied film samples are manufactured using the same batch of clear glass to allow for an investigation of the accuracy in the Optics 5 laminate deconstruction process. The IGDB contains optical information in the wavelength region between 300-2500 nm where transmittance as well as reflectance for both the front and the back surface is recorded. In addition to that emissivity, obtained through measurement of reflectance between 5 and 25 m, is recorded for both the front and back surface. The goal for submitters is to pass within the tolerances dictated by NFRC document 302 which states that transmittances should be within 1% and reflectance/emissivity withing 2%. As an organizing entity LBNL aims to educate and help submitters troubleshoot any issues that give rise to systematic errors. The ILC is a living ILC and does not necessarily contain the first result submitted by a lab. As errors are found submitters are encouraged to correct procedures or update equipment so that they are allowed to submit data to the IGDB. The risk of this practice is that if any of the recommended solutions introduces new systematic errors this will start to influence the average. Therefore this report tries to highlight the recommendations made so that they can be challenged.

  14. Resulting alterations at the level of testes and semen in dogs submitted to vincristine sulphate administra tion

    Directory of Open Access Journals (Sweden)

    Carlos Roberto Daleck

    1995-03-01

    Full Text Available Sperm analysis and testicular histological studies were performed before and after vincristine sulphate treatment, in fourteen male dogs. In group I (n = 8, unilateral orchiectomy was carried out before and after mitostatic treatment, and testicular and epididymal biopsies were examined histologically. All histological examinations showed a slight to moderate degeneration of testicular tissue. In group II (n = 6 semen was collected and was submitted to laboratorial analysis. After vincristine treatment, middle piece and tail abnormalities were found. However, as physical and morphological abnormalities showed to be reversible, vincristine sulphate therapy may be used in such species.

  15. Evaluation "in situ" of tag formation in dental enamel submitted to microabrasion technique. Effect of two etching times.

    Science.gov (United States)

    Hoeppner, Márcio G; Mauro, Silvio J; Alexandre, Rodrigo S; Sundefeld, Maria L M M; Sundfeld, Renato H

    2010-01-01

    The objective of this study was to analyze the formation of resin tags on enamel surfaces submitted or not to enamel microabrasion technique. Thirteen undergraduate dental students received removable acrylic palatal appliances on which four sections from intact premolars were fixed, measuring 4.0 mm x 4.0 mm. Two sections received the application of a microabrasive system and the remaining sections did not receive any surface treatment. The patients were instructed to wear the acrylic palatal appliances for 4 months during the day. After this time, the sections were etched with 37% phosphoric acid for 15 seconds (sections 1 and 2) and 60 seconds (sections 3 and 4), followed by adhesive system and composite resin applications. All the sections were prepared for light microscopy analysis to observe the degree of resin penetration (x400). The results were submitted to a three-way analysis of variance with a significance level of 5%. The difference between groups was verified by the Tukey test, at a significance level of 5%. The results showed that microabraded enamel required a longer period of acid etching for longer resin tags.

  16. ERK is involved in the reorganization of somatosensory cortical maps in adult rats submitted to hindlimb unloading.

    Directory of Open Access Journals (Sweden)

    Erwan Dupont

    Full Text Available Sensorimotor restriction by a 14-day period of hindlimb unloading (HU in the adult rat induces a reorganization of topographic maps and receptive fields. However, the underlying mechanisms are still unclear. Interest was turned towards a possible implication of intracellular MAPK signaling pathway since Extracellular-signal-Regulated Kinase 1/2 (ERK1/2 is known to play a significant role in the control of synaptic plasticity. In order to better understand the mechanisms underlying cortical plasticity in adult rats submitted to a sensorimotor restriction, we analyzed the time-course of ERK1/2 activation by immunoblot and of cortical reorganization by electrophysiological recordings, on rats submitted to hindlimb unloading over four weeks. Immunohistochemistry analysis provided evidence that ERK1/2 phosphorylation was increased in layer III neurons of the somatosensory cortex. This increase was transient, and parallel to the changes in hindpaw cortical map area (layer IV. By contrast, receptive fields were progressively enlarged from 7 to 28 days of hindlimb unloading. To determine whether ERK1/2 was involved in cortical remapping, we administered a specific ERK1/2 inhibitor (PD-98059 through osmotic mini-pump in rats hindlimb unloaded for 14 days. Results demonstrate that focal inhibition of ERK1/2 pathway prevents cortical reorganization, but had no effect on receptive fields. These results suggest that ERK1/2 plays a role in the induction of cortical plasticity during hindlimb unloading.

  17. Mechanical properties of one and two-step fluoridated orthodontic resins submitted to different pH cycling regimes

    Directory of Open Access Journals (Sweden)

    Paula Passalini

    2010-06-01

    Full Text Available The aim of this study is to assess the in vitro shear bond strength and adhesive remnant index (ARI of one and two-step fluoridated orthodontic resins under conditions that simulate high cariogenic challenge. Edgewise brackets for maxillary central incisors were randomly bonded to 80 bovine incisors, using either TransbondTM Plus Color Change orthodontic resin and a self-etching primer adhesive (G1; n = 40 or Orthodontic Fill Magic with a conventional acid-etch technique (G2; n = 40. Each group of resin (n = 10 was divided into: immediate shear (A- pre-cycling control, immersion in artificial remineralizing saliva (neutral saliva for 14 days (B- post-cycling control and pH cycling with high cariogenic challenge (C- acid saliva with pH 5.5 and D- acid saliva with pH 4.5. After 14 days of pH cycling, the shear bond strength and ARI were evaluated. Considering the shear bond strength, TransbondTM Plus Color Change resin was stronger than Orthodontic Fill Magic when it was submitted to high cariogenic challenge (p < 0.05. Also TransbondTM Plus Color Change resin showed better adhesion to enamel than Orthodontic Fill Magic, in all situations evaluated (p < 0.05. It could be concluded that TransbondTM Plus Color Change resin presented better shear bond strength and adhesive remnant index when submitted to high cariogenic challenge, in comparison with Orthodontic Fill Magic.

  18. Preliminary assays for lemongrass essential oil ecotoxicological test in D. similis and C. silvestrii submitted to gamma radiation

    Energy Technology Data Exchange (ETDEWEB)

    Gimiliani, Giovana T.; Rogero, Sizue O.; Rogero, Jose R., E-mail: gtgimiliani@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Cruz, Aurea S. [Instituto Adolfo Lutz, Sao Paulo, SP (Brazil). Culturas Celulares

    2011-07-01

    Pharmaceutical products are of great interest in ecotoxicological studies due to being found some of these products in the superficial waters and sediments, water and sewage treatment effluents. It was verified an increase of insect repellent chemical products in the aquatic environment because of the increase of diseases transmitted by mosquitoes like dengue. As these compounds show toxicity, the use of essential oils natural products with repellent properties is increasing and the literature about the impact in the aquatic environment is scarce. The hydric frame would suffer natural radiation and radiations from energy generation nuclear plants impacts fall out of tests and nuclear accidents. There is no universal definition of environmental protection and there are few studies on radiation effects in the aquatic environment. In this study was determined the lemon grass essential oil toxicity level as well as the lethal dose of ionizing radiation, LD{sub 50}, in aquatic organisms. Cytotoxicity test was performed by in vitro neutral red uptake method in NCTC clone L929 cell line. In the LD{sub 50} test aquatic organisms were submitted to gamma radiation. The essential oil of lemongrass Cymbopogon flexuosus showed cytotoxicity index IC{sub 50} about 50{mu}g.mL{sup -1}. The LD{sub 50} for Daphnia similis was 242 Gy and Ceriodaphnia silvestrii about 525 Gy. Studies will be continued with acute and chronic ecotoxicological tests of lemongrass essential oil in natural organisms and in organisms submitted to gamma radiation, utilizing the results obtained in this work. (author)

  19. Structural characterization of annatto seeds (Bixa orellana) by transmission and scanning electron microscopy submitted to gamma radiation for dormancy break

    Energy Technology Data Exchange (ETDEWEB)

    Harder, Marcia N.C.; Nogueira, Neusa L.; Arthur, Valter; Rossi, Monica L.; Rodriguez, Adriana P.M. [Centro de Energia Nuclear na Agricultura (CENA/USP), Piracicaba, SP (Brazil)]. E-mails: mnharder@cena.usp.br; nogueira@cena.usp.br; arthur@cena.usp.br; mnicalr@cena.usp.br; riana@cena.usp.br

    2007-07-01

    The annatto (Bixa orellana) is the only species of the Bixaceae family. From the seeds an important food colorant is obtained, bixin, for the industry and domestic use. More recently studies have focused more extensively in medicinal purpose of the species. Due to structural and physiologic characteristics, the seeds have low germination rate, around 30 %. The irradiation of seeds with gamma radiation can promote the increase and/or acceleration of germination, better plant development and productivity, among other aspects. The radiation doses used for this purpose should not cause genetic modifications in the organism, hence experimentation is needed to define the appropriate doses. Absence of research done annatto related to the use of the irradiation aiming at the increase of germination rates lead to the structural characterization of the annatto seeds submitted to gamma radiation through transmission (TEM) and scanning electron microscopy (SEM). The objective of this study was to verify the effect of radiation on the seeds structures during the process of dormancy break. Dry seeds and seeds immersed in distilled water for 24 hours were submitted to gamma radiation from source of Co{sup 60} type Gammacell-220 at CENA/USP, at doses 100 Gy. After irradiation the seeds were processed for TEM and SEM. Preliminary results, showed structural modifications in the seeds. (author)

  20. PEEP-ZEEP technique: cardiorespiratory repercussions in mechanically ventilated patients submitted to a coronary artery bypass graft surgery

    Directory of Open Access Journals (Sweden)

    Auler José

    2011-09-01

    Full Text Available Abstract Background The PEEP-ZEEP technique is previously described as a lung inflation through a positive pressure enhancement at the end of expiration (PEEP, followed by rapid lung deflation with an abrupt reduction in the PEEP to 0 cmH2O (ZEEP, associated to a manual bilateral thoracic compression. Aim To analyze PEEP-ZEEP technique's repercussions on the cardio-respiratory system in immediate postoperative artery graft bypass patients. Methods 15 patients submitted to a coronary artery bypass graft surgery (CABG were enrolled prospectively, before, 10 minutes and 30 minutes after the technique. Patients were curarized, intubated, and mechanically ventilated. To perform PEEP-ZEEP technique, saline solution was instilled into their orotracheal tube than the patient was reconnected to the ventilator. Afterwards, the PEEP was increased to 15 cmH2O throughout 5 ventilatory cycles and than the PEEP was rapidly reduced to 0 cmH2O along with manual bilateral thoracic compression. At the end of the procedure, tracheal suction was accomplished. Results The inspiratory peak and plateau pressures increased during the procedure (p Conclusion The PEEP-ZEEP technique seems to be safe, without alterations on hemodynamic variables, produces elevated expiratory flow and seems to be an alternative technique for the removal of bronchial secretions in patients submitted to a CABG.

  1. Restoring sinus rhythm in patients with previous pacemaker implantation submitted to cardiac surgery and concomitant surgical ablation of atrial fibrillation.

    Science.gov (United States)

    Marques, Marta P; Melo, João Q; Knaut, Michel; Alfieri, Ottavio; Benussi, Stefano; Williams, Mathew R; Hornero, Fernando

    2008-04-01

    Some patients submitted to cardiac surgery have concomitant atrial fibrillation and a previously implanted pacemaker. Because it is unknown if there is any potential for these patients to reassume a regular rate sinus rhythm after ablation of atrial fibrillation, we reviewed the results of all patients with pacemaker enrolled in the Registry of Atrial Fibrillation. Thirty-six patients were included in this study. Twenty-six had valve disease, seven had coronary disease and three had congenital heart disease. They were submitted concomitantly to ablation of atrial fibrillation using biatrial approaches (seven patients), left sided (27), or right sided (three patients). Thirty-three hospital survivors had a mean follow-up of 18 months, and a maximum of 25 months. At 1 year (n=21), patients' rhythm was sinus non-pacing dependent (52%), sinus pacing-dependent (14%), and atrial fibrillation (14%). At 2 years (n=14), patients' rhythm was sinus non-pacing dependent (57%) and atrial fibrillation (43%). The only factor that may have had impact on the recovery of sinus rhythm at 1 year was the small size of the left atrium (p=0.05). We conclude that in a significant number of patients, having a pacemaker before surgery does not preclude sinus rhythm recovery after a cardiac operation and ablation for concomitant atrial fibrillation.

  2. Lactated Ringer's solution or 0.9% sodium chloride as fluid therapy in pigeons (Columba livia submitted to humerus osteosynthesis

    Directory of Open Access Journals (Sweden)

    Adriano B. Carregaro

    2015-01-01

    Full Text Available The study aimed to compare the effects of intraosseous infusion of lactated Ringer's and 0.9% sodium chloride solutions on the electrolytes and acid-base balance in pigeons submitted to humerus osteosynthesis. Eighteen pigeons were undergoing to isoflurane anesthesia by an avalvular circuit system. They were randomly assigned into two groups (n=9 receiving lactated Ringer's solution (LR or 0.9% sodium chloride (SC, in a continuous infusion rate of 20mL/kg/h, by using an intraosseous catheter into the tibiotarsus during 60-minute anesthetic procedure. Heart rate (HR, and respiratory rate (RR were measured every 10 min. Venous blood samples were collected at 0, 30 and 60 minutes to analyze blood pH, PvCO2, HCO3 -, Na+ and K+. Blood gases and electrolytes showed respiratory acidosis in both groups during induction, under physical restraint. This acidosis was evidenced by a decrease of pH since 0 min, associated with a compensatory response, observed by increasing of HCO3 - concentration, at 30 and 60 min. It was not observed any changes on Na+ and K+ serum concentrations. According to the results, there is no reason for choosing one of the two solutions, and it could be concluded that both fluid therapy solutions do not promote any impact on acid-base balance and electrolyte concentrations in pigeons submitted to humerus osteosynthesis.

  3. Study of tensiometric properties, microbiological and collagen content in nile tilapia skin submitted to different sterilization methods.

    Science.gov (United States)

    Alves, Ana Paula Negreiros Nunes; Lima Júnior, Edmar Maciel; Piccolo, Nelson Sarto; de Miranda, Marcelo José Borges; Lima Verde, Maria Elisa Quezado; Ferreira Júnior, Antônio Ernando Carlos; de Barros Silva, Paulo Goberlânio; Feitosa, Victor Pinheiro; de Bandeira, Tereza Jesus Pinheiro Gomes; Mathor, Monica Beatriz; de Moraes, Manoel Odorico

    2018-01-29

    Tissue bioengineering development is a global concern and different materials are studied and created to be safe, effective and with low cost. Nile Tilapia skin had shown its biological potential as covers for the burn wound. This study evaluates the tilapia skin histological, collagen properties and tensiometric resistance, after treatment by different sterilization methods. Tilapia skin samples were submitted to two sterilization processes: (1) chemical, which consisted in two 2% chlorhexidin baths, followed by sequential baths in increasing glycerol concentrations; and (2) radiation, when glycerolized skin samples were submitted to gamma radiation at 25, 30 and 50 kGy. Microscopic analyzes were performed through Haematoxylin-eosin and Picrosirius Red under polarized light. For tensiometric analysis, traction tests were performed. Glycerol treated skin presented a discrete collagen fibers disorganization within the deep dermis, while irradiated skin did not show any additional change. Throughout the steps of chemical sterilization, there was a higher proportion of collagen with red/yellow birefringence (type I) in the skin samples up to the first bath in chlorhexidin, when compared to samples after the first two glycerol baths (P skin, there was a larger total collagen preservation when using until 30 kGy (P Tilapia skin without altering its microscopic or tensiometric characteristics.

  4. Ethical considerations in malaria research proposal review: empirical evidence from 114 proposals submitted to an Ethics Committee in Thailand.

    Science.gov (United States)

    Adams, Pornpimon; Prakobtham, Sukanya; Limphattharacharoen, Chanthima; Vutikes, Pitchapa; Khusmith, Srisin; Pengsaa, Krisana; Wilairatana, Polrat; Kaewkungwal, Jaranit

    2015-09-14

    Malaria research is typically conducted in developing countries in areas of endemic disease. This raises specific ethical issues, including those related to local cultural concepts of health and disease, the educational background of study subjects, and principles of justice at the community and country level. Research Ethics Committees (RECs) are responsible for regulating the ethical conduct of research, but questions have been raised whether RECs facilitate or impede research, and about the quality of REC review itself. This study examines the review process for malaria research proposals submitted to the Ethics Committee of the Faculty of Tropical Medicine at Mahidol University, Thailand. Proposals for all studies submitted for review from January 2010 to December 2014 were included. Individual REC members' reviewing forms were evaluated. Ethical issues (e.g., scientific merit, risk-benefit, sample size, or informed-consent) raised in the forms were counted and analysed according to characteristics, including study classification/design, use of specimens, study site, and study population. All 114 proposals submitted during the study period were analysed, comprising biomedical studies (17 %), drug trials (13 %), laboratory studies (24 %) and epidemiological studies (46 %). They included multi-site (13 %) and international studies (4 %), and those involving minority populations (28 %), children (17 %) and pregnant women (7 %). Drug trials had the highest proportion of questions raised for most ethical issues, while issues concerning privacy and confidentiality tended to be highest for laboratory and epidemiology studies. Clarifications on ethical issues were requested by the ethics committee more for proposals involving new specimen collection. Studies involving stored data and specimens tended to attract more issues around privacy and confidentiality. Proposals involving minority populations were more likely to raise issues than those that did not

  5. The postural control can be optimized by the first movement initiation condition encountered when submitted to muscle fatigue.

    Science.gov (United States)

    Monjo, Florian; Forestier, Nicolas

    2017-08-01

    We investigated whether and how the movement initiation condition (IC) encountered during the early movements performed following focal muscle fatigue affects the postural control of discrete ballistic movements. For this purpose, subjects performed shoulder flexions in a standing posture at maximal velocity under two movement IC, i.e., in self-paced conditions and submitted to a Stroop-like task in which participants had to trigger fast shoulder flexions at the presentation of incongruent colors. Shoulder flexion kinematics, surface muscle activity of focal and postural muscles as well as center-of-pressure kinematics were recorded. The initial IC and the order in which subjects were submitted to these two conditions were varied within two separate experimental sessions. IC schedule was repeated before and after fatigue protocols involving shoulder flexors. The aim of this fatigue procedure was to affect acceleration-generating capacities of focal muscles. In such conditions, the postural muscle activity preceding and accompanying movement execution is expected to decrease. Following fatigue, when subjects initially moved in self-paced conditions, postural muscle activity decreased and scaled to the lower focal peak acceleration. This postural strategy then transferred to the Stroop-like task. In contrast, when subjects initially moved submitted to the Stroop-like task, postural muscle activity did not decrease and this transferred to self-paced movements. Regarding the center-of-pressure peak velocity, which is indicative of the efficiency of the postural actions generated in stabilizing posture, no difference appeared between the two sessions post-fatigue. This highlights an optimization of the postural actions when subjects first moved in self-paced conditions, smaller postural muscle activation levels resulting in similar postural consequences. In conclusion, the level of neuromuscular activity associated with the postural control is affected and can be

  6. Reporting of ethical review of clinical research submitted to the Journal of the American Academy of Dermatology.

    Science.gov (United States)

    Perkins, Alexis C; Choi, Joanna Mimi; Kimball, Alexa B

    2007-02-01

    In recent years there has been an increasing focus on human subject protection and on documentation of ethical review in published clinical research. The JAAD clearly states in its instructions to authors, which adhere to the guidelines set forth by the International Committee of Medical Journal Editors, "studies involving live human subjects must have been approved by the author's Institutional Review Board or its equivalent." To determine what proportion of prospective studies on human subjects submitted to the clinical trials and therapeutics section lacked mention of review by an ethics board and to determine the outcome of these manuscripts. We reviewed 150 prospective studies submitted from July 1, 2004 to January 16, 2006 to a single associate editor, who receives the majority of reports requiring ethics board review. Of 150 prospective studies, 36% (n = 54) had no mention of ethics review or consent, whereas 15% (n = 22) mentioned consent but not ethics review. Forty-two papers were returned asking for ethics information, and of these, 48% were resubmitted with confirmation of ethics review, 22% were withdrawn, 12% were never resubmitted, 12% responded that ethical review was not obtained, and 7% were clarified as exempt from review. Of the 150 papers, 45% were from US authors and 55% were from international authors. Sixty-seven percent of US papers and 35% of international papers included ethics board information (P

  7. 76 FR 31320 - Commission Information Collection Activities (FERC-725B); Comment Request; Submitted for OMB Review

    Science.gov (United States)

    2011-05-31

    ... legal personnel. \\11\\ Based on the aggregate cost of an IBM advanced data protection server. The... remotely via the Internet through FERC's homepage using the ``eLibrary'' link. For user assistance, contact...

  8. 76 FR 19333 - Commission Information Collection Activities (FERC-725B); Comment Request; Submitted for OMB Review

    Science.gov (United States)

    2011-04-07

    ... advanced data protection server. The reporting burden includes the total time, effort, or financial... comments may be viewed, printed or downloaded remotely via the Internet through FERC's homepage using the...

  9. The value of superpower-submitted INDCs in cooperative and non-cooperative action scenarios: economic impact, dynamic risk, and temperature rise

    Science.gov (United States)

    Augustin, C. M.

    2015-12-01

    As the 2015 Paris climate talks near, policy discussions are focused on "intended nationally determined contributions" (INDCs) submitted in advance of the discussions. As the major global emitters - specifically the United States and China - have already submitted their INDCs, we have a point of comparison for evaluating the relative potential impacts of the proposed targets. By applying integrated assessment models to robust, publicly available data sets,we aim to evaluate the interplay between climate change and economic development, comment on emissions reduction scenarios in cooperative and non-cooperative situations, and assess the dynamic risks of multiple regional emissions scenarios. We use both the RICE model and the C-ROADS model to examine alternative regional outcomes for emissions, climate change, and damages,under different reduction scenarios, including a scenario where geo-engineering plays a prominent role. These simulators allow us to vary emissions, population, and economic levels in China and the United States specifically to comment on the international climate risk impact of actors working jointly - or not - toward a global climate goal. In a complementary piece of analysis we seek to understand the value judgments, trade-offs, and regional policies that would lead to favorable climate finance flows. To reach an international sample of industry decision-makers, we propose a novel application of a standard discrete-choice survey methodology. A conjoint analysis requires a participant to chose between combinations of attributes and identify trade-offs while allowing the researcher to determine the relative importance of each individual attribute by mathematically assessing the impact each attribute could have on total item utility. As climate policy negotiations will consist of allocation of scarce resources and rejection of certain attributes, a conjoint analysis is an ideal tool for evaluating policy outcomes. This research program seeks to

  10. Tuberculosis patients submitted to supervised treatment. Ribeirão Preto-São Paulo-Brazil. 1998 and 1999.

    Science.gov (United States)

    Hino, Paula; dos Santos, Claudia Benedita; Villa, Tereza Cristina Scatena; Muniz, Jordana Nogueira; Monroe, Aline Aparecida

    2005-01-01

    This study presents a survey conducted among 132 Tuberculosis patients submitted to Supervised Treatment between 01/1998 and 12/1999, with a view to describing epidemiological aspects, according to the gender, (final) treatment result and HIV immunology result variables. The number of patients covered by Supervised Treatment rose from 19% to 30%. For each of these years, 64% and 71% of the patients were male, while 89% and 77% evolved towards cure. The rate of abandonment increased from 7% to 10%, while 4% and 10% of the patients died of Tuberculosis. The Tb/HIV co-infection represented 22% and 42% of the cases. The obtained results disclosed a tendency towards the gradual amplification of Supervised Treatment and its implementation implied.

  11. Productivity and production efficiency of cows of different genetic groups submitted to cultivated pastures during pre or postpartum

    Directory of Open Access Journals (Sweden)

    Ricardo Zambarda Vaz

    2014-10-01

    Full Text Available We assessed through the weight of cows and calves up to weaning at 90 days and the reproductive performance from pregnancy to weaning, the productivity and efficiency of 94 Charolais (CH, Nellore (NE, ½CH ½NE e ½NE ½CH cows submitted the following feeding systems: cows kept on native pasture (NP; cows kept on cultivated pasture (CP, composed of oat (Avena sativa, ryegrass (Lollium multiflorum and clover (Trifolium vesiculosum from July 15 to September 15 and the remainder of the trial on natural pasture (CPN; and cows kept on cultivated pasture during September 15 to November 15, and the remainder on native pasture (NPC. Cows kept on CP produced 22.6% more calves than cows kept exclusively on NP, and were more efficient (P.05, being higher than the purebreds in productivity and production efficiency

  12. Experimental assessment of the surface temperature of copper electrodes submitted to an electric arc in air at atmospheric pressure

    Energy Technology Data Exchange (ETDEWEB)

    Landfried, R; Leblanc, T; Andlauer, R; Teste, Ph, E-mail: teste@lgep.supelec.fr [Laboratoire de Genie Electrique de Paris : SUPELEC - CNRS - Universites Paris VI et Paris XI - Plateau de Moulon - 91192 Gif sur Yvette Cedex (France)

    2011-01-01

    This paper concerns the assessment of the surface temperature of copper electrodes submitted to an electric arc in a non stationary regime in air. An infrared camera is used to measure the decrease of the temperature surface just after a controlled and very fast arc extinction. In the first part, the experimental method is described. In the second part, results are presented for 60-70 A with an electric arc duration in the range 3-4 ms. The temperature decrease after the arc extinction allows to reach an assessment of the surface temperature just at the arc switching off. In the present experimental conditions the mean temperatures reached for copper cathodes and anodes are in the range 750-850 deg. C.

  13. An analysis of the titles of papers submitted to the UK REF in 2014: authors, disciplines, and stylistic details.

    Science.gov (United States)

    Hudson, John

    2016-01-01

    In 2014 over 52,000 academics submitted >155,500 journal articles in 36 different disciplines for assessment in the UK's four-year Research Evaluation Framework (the REF). In this paper the characteristics of the titles of these papers are assessed. Although these varied considerably between the disciplines, the main findings were that: (i) the lengths of the titles increased with the number of authors in almost all disciplines, (ii) the use of colons and question marks tended to decline with increasing author numbers-although there were a few disciplines, such as economics, where the reverse was evident, (iii) papers published later on in the 4-year period tended to have more authors than those published earlier, and (iv), in some disciplines, the numbers of subsequent citations to papers were higher when the titles were shorter and when they employed colons but lower when they used question marks.

  14. Assessment of facial profile changes in Class I biprotrusion adolescent subjects submitted to orthodontic treatment with extractions of four premolars

    Directory of Open Access Journals (Sweden)

    Claudia Trindade Mattos

    2012-06-01

    Full Text Available OBJECTIVE: To evaluate cephalometric changes in tooth and profile position in young adolescent individuals with Class I biprotrusion submitted to orthodontic treatment with extractions of four first premolars. METHODS: Pre and posttreatment lateral cephalometric radiographs from 20 patients with Class I biprotrusion malocclusion were used to evaluate the following measurements: nasolabial angle, distance from lips to E line, distance from lips, incisors, tip of the nose and soft tissue pogonion to Sy line. RESULTS: All measurements showed significant changes after treatment (p<0.05, except the distance from lips and soft tissue pogonion to Sy line. There was a positive correlation between the retraction of incisors and the change of upper and lower lips (0.803/0.925; p<0.001. CONCLUSION: The profile retrusion observed occurred more due to nose growth than to lips retraction. The response from soft tissues to incisors retraction showed a great variability.

  15. Depressive symptoms and cognitive deficits in a cancer patient submitted to chemotherapy with 5-Fluoracil: A case report

    Directory of Open Access Journals (Sweden)

    Sara Mota Borges Bottino

    Full Text Available ABSTRACT Cognitive deficits in cancer patients can be related to depression, anxiety, and the side effects of treatments such as fatigue. In this case report, we described an elderly patient with rectal adenocarcinoma, which presented depressive symptoms and memory complaints after treatment with 5-Fluoracil and Leucovorin. Depressive symptoms improved after two months but cognitive and functional impairment worsened suggesting the diagnosis of mild dementia. Structural and functional brain changes were seen on neuroimaging exams. Rivastigmine was introduced up to 12 mg/day, and after a one-year follow up the patient remained stable. Cognitive deficits can be a consequence of cancer therapies and a protocol to investigate deficits cognitive could be useful to the diferential diagnosis and management of elderly cancer patients submitted to chemotherapy.

  16. Survey of editors and reviewers of high-impact psychology journals: statistical and research design problems in submitted manuscripts.

    Science.gov (United States)

    Harris, Alex; Reeder, Rachelle; Hyun, Jenny

    2011-01-01

    The authors surveyed 21 editors and reviewers from major psychology journals to identify and describe the statistical and design errors they encounter most often and to get their advice regarding prevention of these problems. Content analysis of the text responses revealed themes in 3 major areas: (a) problems with research design and reporting (e.g., lack of an a priori power analysis, lack of congruence between research questions and study design/analysis, failure to adequately describe statistical procedures); (b) inappropriate data analysis (e.g., improper use of analysis of variance, too many statistical tests without adjustments, inadequate strategy for addressing missing data); and (c) misinterpretation of results. If researchers attended to these common methodological and analytic issues, the scientific quality of manuscripts submitted to high-impact psychology journals might be significantly improved.

  17. [Analysis of evaluation process of research projects submitted to the Fondo de Investigación Sanitaria, Spain].

    Science.gov (United States)

    Prieto Carles, C; Gómez-Gerique, J; Gutiérrez Millet, V; Veiga de Cabo, J; Sanz Martul, E; Mendoza Hernández, J L

    2000-10-07

    At the present time it seems very clear that research improvement is both an unquestionable fact and the right way to develop technological innovation, services and patents. However, such improvement and corresponding finances needs to be done under fine and rigorous evaluation process as an assessment tool under which all the research projects applying to a public or private call for proposals should be submitted to assure a coherence point according to the investment to be made. At this end, the main target of this work has been focused to analysis and study the evaluation process traditionally made by Fondo de Investigación Sanitaria (FIS) as well as to propose most adequate modifications. A sample of 431 research projects corresponding to year 1998 proposal was analysed. The evaluation from FIS and ANEP (National Evaluation and Prospective Agency) was evaluated and scored (evaluation quality) in its main contents by 3 independent evaluators, the showed results submitted to a comparative frame between these agencies at indoor (FIS) and outdoor (FIS/ANEP) level. FIS evaluation had 20 commissions or areas of knowledge. The analysis indoor (FIS) clearly showed that evaluation quality was correlated to the assigned commission (F = 3.71; p < 0.001) and to the time last of the researched proposal (F = 3.42; p < 0.05) but no related to the evaluator. On the other hand, the quality of ANEP evaluation showed a correlated dependency of the three mentioned facts. In all terms, the ANEP evaluation was better than FIS for the three years time projects, but in did not show significant differences in one or two years time projects. In all cases, the evaluation with final results as negative (financing denied) showed an average quality higher than positive evaluation. The obtained results advice about the convenience of making some changes in the evaluative structure and to review the sort of FIS technical commissions focusing an improvement of the evaluation process.

  18. Evaluating laboratory request forms submitted to haematology and blood transfusion departments at a hospital in Northwest Nigeria

    Directory of Open Access Journals (Sweden)

    Feyisayo Jegede

    2016-02-01

    Full Text Available Background: The laboratory request form (LRF is a communication link between laboratories, requesting physicians and users of laboratory services. Inadequate information or errors arising from the process of filling out LRFs can significantly impact the quality of laboratory results and, ultimately, patient outcomes.Objective: We assessed routinely-submitted LRFs to determine the degree of correctness, completeness and consistency.Methods: LRFs submitted to the Department of Haematology (DH and Blood Transfusion Services (BTS of Aminu Kano Teaching Hospital in Kano, Nigeria, between October 2014 and December 2014, were evaluated for completion of all items on the forms. Performance in four quality indicator domains, including patient identifiers, test request details, laboratory details and physician details, was derived as a composite percentage.Results: Of the 2084 LRFs evaluated, 999 were from DH and 1085 from BTS. Overall, LRF completeness was 89.5% for DH and 81.2% for BTS. Information on patient name, patient location and laboratory number were 100% complete for DH, whereas only patient name was 100% complete for BTS. Incomplete information was mostly encountered on BTS forms for physician’s signature (60.8% and signature of laboratory receiver (63.5%. None of the DH and only 9.4% of BTS LRFs met all quality indicator indices.Conclusion: The level of completion of LRFs from these two departments was suboptimal. This underscores the need to review and redesign the LRF, improve on training and communication between laboratory and clinical staff and review specimen rejection practices.

  19. A comparison of detomidine in combination with saline, morphine or methadone in horses submitted to experimental oral stimuli

    Directory of Open Access Journals (Sweden)

    Rafael Costa Guilhen

    2015-12-01

    Full Text Available This study aimed to compare the sedative and cardiopulmonary effects of detomidine in combination with saline, morphine or methadone and to determine whether the addition of these opioids increases the degree of sedation in horses submitted to experimental oral stimuli. In a blinded, randomized, experimental study, six adult mares were evaluated using a crossover design with at least 15 days between trials: 10?g/kg detomidine in combination with saline (D/SAL, 0.1mg/kg morphine (D/ MORPH or 0.1mg/kg methadone (D/METH. The degree of sedation, response to oral stimuli and cardiopulmonary parameters were monitored for 120 minutes. Parametric data were analyzed using the ANOVA and Tukey’s tests, and non- parametric data were analyzed with the Kruskal-Wallis and Friedman’s tests with the post-Dunn test (P<0.05. The degree of sedation was significantly greater for the D/SAL than for the D/MORPH and D/METH treatments at 30 min. The horses´ responses to the oral stimuli decreased significantly following all treatments at 5 and 30 min from baseline values. The heart rate, respiratory rate, arterial pH and blood gas variables were all similar among the treatment groups. Mean arterial blood pressure was significantly higher in the D/MORPH group when compared with the D/SAL group between 75 and 120 min. It was concluded that all treatments provided sedative effects with mild cardiopulmonary changes. However the addition of morphine or methadone to detomidine did not improve the degree of sedation in horses submitted to experimental oral stimuli.

  20. Effects of orofacial myofunctional therapy on masticatory function in individuals submitted to orthognathic surgery: a randomized trial.

    Science.gov (United States)

    Prado, Daniela Galvão de Almeida; Berretin-Felix, Giédre; Migliorucci, Renata Resina; Bueno, Mariana da Rocha Salles; Rosa, Raquel Rodrigues; Polizel, Marcela; Teixeira, Isadora Ferraz; Gavião, Maria Beatriz Duarte

    2018-02-01

    The esthetic and functional results of orthognathic surgery of severe dentofacial deformities are predictable, however there are differences regarding the effects on stomatognathic system. The aim was to investigate the effects of orofacial myofunctional therapy (OMT) on the masticatory function in individuals with dentofacial deformity submitted to orthognathic surgery (OGS). Forty-eight individuals (18-40 years) were evaluated, 14 undergoing OMT (treated group-TG), 10 without this treatment (untreated group-UTG) and 24 in a control group with normal occlusion; for clinical aspects the data of an individual was missed (n=46). Chewing was performed using the Expanded protocol of orofacial myofunctional evaluation with scores (OMES-E). Muscle tone and mobility were also analyzed before (P0), three (P1) and six months (P2) after OGS. Surface electromyography of the masseter and temporalis muscles was performed, considering the parameters amplitude and duration of act and cycle, and the number of masticatory cycles. The OMT consisted of ten therapeutic sessions along the postoperative period. The results were compared using parametric and non-parametric tests. TG showed higher scores in P1 and P2 than P0; for the masticatory type the scores in P2 were significantly higher than P0. In addition, the proportion of individuals with adequate tone of lower lip and adequate tongue mobility for TG increased significantly from P1 and P2 in relation to P0. The EMG results showed a decrease in act and cycle duration in P2 in relation to P0 and P1 for the TG; furthermore the values were close to controls. An increase in the number of cycles from P0 to P2 was also observed, indicating faster chewing, which may be attributed to an improvement of balanced occlusion associated with OMT. There were positive effects of OMT on the clinical and electromyography aspects of chewing in individual submitted to orthognathic surgery.

  1. Effect of Erythrina velutina and Erythrina mulungu in rats submitted to animal models of anxiety and depression

    Directory of Open Access Journals (Sweden)

    M.D. Ribeiro

    2006-02-01

    Full Text Available Erythrina velutina (EV and Erythrina mulungu (EM, popularly used in Brazil as tranquilizing agents, were studied. The effects of acute and chronic oral treatment with a water:alcohol extract of EV (7:3, plant grounded stem bark; acute = 100, 200, 400 mg/kg; chronic = 50, 100, 200 mg/kg were evaluated in rats (N = 11-12 submitted to the elevated T-maze (for avoidance and escape measurements model of anxiety. This model was selected for its presumed capacity to elicit specific subtypes of anxiety disorders recognized in clinical practice: avoidance has been related to generalized anxiety and escape to panic. Additionally, animals were treated with the same doses of EV and EM (water:alcohol 7:3, inflorescence extract and submitted to the forced swim test for the evaluation of antidepressant activity (N = 7-10. Both treatment regimens with EV impaired elevated T-maze avoidance latencies, without altering escape, in a way similar to the reference drug diazepam (avoidance 1, mean ± SEM, acute study: 131.1 ± 45.5 (control, 9.0 ± 3.3 (diazepam, 12.7 ± 2.9 (200 mg/kg, 28.8 ± 15.3 (400 mg/kg; chronic study: 131.7 ± 46.9 (control, 35.8 ± 29.7 (diazepam, 24.4 ± 10.4 (50 mg/kg, 29.7 ± 11.5 (200 mg/kg. Neither EV nor EM altered measurements performed in the forced swim test, in contrast to the reference drug imipramine that significantly decreased immobility time after chronic treatment. These results were not due to motor alterations since no significant effects were detected in an open field. These observations suggest that EV exerts anxiolytic-like effects on a specific subset of defensive behaviors which have been associated with generalized anxiety disorder.

  2. An epidemiologic study of antimicrobial resistance of Staphylococcus species isolated from equine samples submitted to a diagnostic laboratory.

    Science.gov (United States)

    Adams, Ronita; Smith, Jackie; Locke, Stephen; Phillips, Erica; Erol, Erdal; Carter, Craig; Odoi, Agricola

    2018-02-05

    Antimicrobial resistance limits traditional treatment options and increases costs. It is therefore important to estimate the magnitude of the problem so as to provide empirical data to guide control efforts. The aim of this study was to investigate the burden and patterns of antimicrobial resistance (AMR) among equine Staphylococcus samples submitted to the University of Kentucky Veterinary Diagnostic Laboratory (UKVDL) from 1993 to 2009. Retrospective data of 1711 equine Staphylococcus samples submitted to the UKVDL during the time period 1993 to 2009 were included in the study. Antimicrobial susceptibility testing, that included 16 drugs, were performed using cultures followed by the Kirby-Bauer disk diffusion susceptibility test. The proportion of resistant isolates by animal breed, species of organism, sample source, and time period were computed. Chi-square and Cochran-Armitage trend tests were used to identify significant associations and temporal trends, respectively. Logistic regression models were used to investigate predictors of AMR and multidrug resistance (MDR). A total of 66.3% of the isolates were resistant to at least one antimicrobial, most of which were Staphylococcus aureus (77.1%), while 25.0% were MDR. The highest level of resistance was to penicillins (52.9%). Among drug classes, isolates had the highest rate of AMR to at least one type of β-lactams (49.2%), followed by aminoglycosides (30.2%). Significant (p resistance to up to 12 antimicrobials, AMR profiles featuring single antimicrobials such as penicillin were more common than those with multiple antimicrobials. Demographic factors were significant predictors of AMR and MDR. The fact that some isolates had resistance to up to 12 of the 16 antimicrobials assessed is quite concerning. To address the high levels of AMR and MDR observed in this study, future studies will need to focus on antimicrobial prescription practices and education of both practitioners and animal owners on judicious

  3. 76 FR 14400 - Proposed Data Collections Submitted for Public Comment and Recommendations

    Science.gov (United States)

    2011-03-16

    ... sitting for a long period of time (e.g., during air travel); having a leg or foot injury; having a family member who has had a DVT; taking birth control pills; or getting older; and certain groups could not... people of all races and ages. Many of the acquired risks such as obesity, advanced age, air travel...

  4. Study of rat hepatocytes in primary culture submitted to hypoxia and reoxygenation: action of the cytoprotectors prostaglandin E1, superoxide dismutase, allopurinol and verapamil.

    Science.gov (United States)

    Andrade Jr, Dahir Ramos de; Andrade, Dahir Ramos de; Santos, Sânia Alves Dos

    2009-01-01

    Exposure of hepatocytes to pathological conditions in a microenvironment of hypoxia and reoxygenation is very frequent in hepatic diseases. Several substances present perspectives for cytoprotective action on hepatocyte submitted to reoxygenation after hypoxia and simple hypoxia. We research therapeutic options for hepatocytes submitted to hypoxia and hypoxia + reoxygenation injury. Primary culture of rat hepatocytes was submitted to hypoxia (2 hours) plus reoxygenation (2 hours) and simple hypoxia (4 hours) in the presence or the absence of cytoprotectors. The hepatocyte lesion was evaluated by functional criteria through percentage of lactate dehydrogenase released and cell viability. The effects of the cytoprotectors prostaglandin E1 3 etag/mL, superoxide dismutase 80 microg/mL, allopurinol 20 microM and verapamil 10-4 M were studied in this model of injury. Reoxygenation after hypoxia induced more significant lesion in cultured hepatocytes compared to simple hypoxia, detected by analysis of functional criteria. There was a significant reduction of percentage of lactate dehydrogenase released and a significant increase of percentage of cell viability in the hypoxia + reoxygenation + cytoprotectors groups compared to hypoxia + reoxygenation groups. Prostaglandin E1, superoxide dismutase and verapamil also protected the group submitted to simple hypoxia, when evaluated by functional criteria. We conclude that reoxygenation after hypoxia significantly increased the lesion of cultured rat hepatocytes when compared to simple hypoxia. Prostaglandin E1, superoxide dismutase, allopurinol and verapamil acted as cytoprotectors to the rat cultured hepatocytes submitted to hypoxia + reoxygenation in vitro. The substances prostaglandin E1, superoxide dismutase and verapamil protected hepatocytes submitted to simple hypoxia on the basis of all the criteria studied in this experimental model.

  5. Microwave Integrated Circuit Amplifier Designs Submitted to Qorvo for Fabrication with 0.09-micron High Electron Mobility Transistors (HEMTs) using 2-mil Gallium Nitride (GaN) on Silicon Carbide (SiC)

    Science.gov (United States)

    2016-03-01

    ARL-TN-0743 ● MAR 2016 US Army Research Laboratory Microwave Integrated Circuit Amplifier Designs Submitted to Qorvo for...originator. ARL-TN-0743 ● MAR 2016 US Army Research Laboratory Microwave Integrated Circuit Amplifier Designs Submitted to Qorvo...To) October 2015–January 2016 4. TITLE AND SUBTITLE Microwave Integrated Circuit Amplifier Designs Submitted to Qorvo for Fabrication with 0.09

  6. Study of influence on harvesting point in Brazilian Tommy Atkins mangoes submitted to gamma radiation

    Science.gov (United States)

    Sabato, S. F.; Cruz, J. N.; Rela, P. R.; Broisler, P. O.

    2009-07-01

    Brazil is a great producer of tropical fruits including mangoes. Among several purposes gamma radiation can be applied as phytosanitary treatment. This is well studied in scientific papers and more recently demonstrated through commercial advances like bilateral protocols established between India and USA. The whole experiment evolved two parts where each of them used fruits from different maturity stages (stages 2 and 3). This experiment was carried out with around 300 fruits in each part of the study. The main objective was to get the experience close to commercial conditions. The irradiation was realized in Multipurpose Cobalt-60 source belonging to IPEN-CNEN/SP (developed in house by own technology). The absorbed doses were 0.2, 0.5 and 0.75 kGy. After irradiation all fruits were kept at 12 °C in acclimatized chamber during 14 days. After this period the fruits were brought to environmental conditions (25 °C) for around 14 more days of duration. These conditions were established to simulate the exportation conditions from Brazil to distant countries. Physical-chemical analysis (pH, titrable acidity, total soluble solids (°Brix) and texture) as well as visual observation (mass loss, rotting, internal and skin color) were evaluated. The results from this experiment could demonstrate that the characteristics of the mangoes are more dependent on time and temperature storage rather than irradiation.

  7. Problem of work on a high energy synchrotron submitted to large radiation dose

    CERN Document Server

    Gouiran, R

    1975-01-01

    Firstly, organic components have to be surveyed and eventually exchanged; secondly, work done by the staff in radioactive areas should be strictly controlled and minimized. To reach these goals radiation and radioactivity should not only be measured but also predicted years in advance. Radiation doses are computed, measured and predicted according to the proton loss pattern around the accelerator. A correlation scheme of doses versus accelerator operation is then deduced to predict the dose on any sensitive part of the accelerator. In the same way a radioactive pattern is computed, measured and accurately predicted in terms of dose rate. Work on the accelerator is studied in detail in order to forecast its duration and the corresponding dose absorbed by the staff. With these methods, it is easy now not only to predict the fate of the equipment and the doses to be received by the staff, but also to organize the work accordingly and possibly to program the accelerator operation (proton intensity and proton uses...

  8. Clinical laboratories collaborate to resolve differences in variant interpretations submitted to ClinVar.

    Science.gov (United States)

    Harrison, Steven M; Dolinsky, Jill S; Knight Johnson, Amy E; Pesaran, Tina; Azzariti, Danielle R; Bale, Sherri; Chao, Elizabeth C; Das, Soma; Vincent, Lisa; Rehm, Heidi L

    2017-10-01

    Data sharing through ClinVar offers a unique opportunity to identify interpretation differences between laboratories. As part of a ClinGen initiative, four clinical laboratories (Ambry, GeneDx, Partners Healthcare Laboratory for Molecular Medicine, and University of Chicago Genetic Services Laboratory) collaborated to identify the basis of interpretation differences and to investigate if data sharing and reassessment resolve interpretation differences by analyzing a subset of variants. ClinVar variants with submissions from at least two of the four participating laboratories were compared. For a subset of identified differences, laboratories documented the basis for discordance, shared internal data, independently reassessed with the American College of Medical Genetics and Genomics-Association for Molecular Pathology (ACMG-AMP) guidelines, and then compared interpretations. At least two of the participating laboratories interpreted 6,169 variants in ClinVar, of which 88.3% were initially concordant. Laboratories reassessed 242/724 initially discordant variants, of which 87.2% (211) were resolved by reassessment with current criteria and/or internal data sharing; 12.8% (31) of reassessed variants remained discordant owing to differences in the application of the ACMG-AMP guidelines. Participating laboratories increased their overall concordance from 88.3 to 91.7%, indicating that sharing variant interpretations in ClinVar-thereby allowing identification of differences and motivation to resolve those differences-is critical to moving toward more consistent variant interpretations.Genet Med advance online publication 09 March 2017.

  9. Cytopathologic evaluation of patients submitted to radiotherapy for uterine cervix cancer

    Directory of Open Access Journals (Sweden)

    Cátia Martins Leite Padilha

    Full Text Available Summary Cervical cancer is an important public health problem. Pap smear is the leading strategy of screening programs for cervical cancer worldwide. However, delayed diagnosis leads to more aggressive and less effective treatments. Patients with uterine cervix malignancies who are referred for radiotherapy have advanced-stage disease, which results in high rates of locoregional recurrence. The use of radiotherapy as a treatment for cervical cancer causes morphological changes in neoplastic and non-neoplastic epithelial cells, as well as in stromal cells, which make it difficult to diagnose the residual lesion, resulting in a dilemma in cytopathological routine. Based on the difficulties of cytopathologic evaluation for the follow-up of patients treated with radiotherapy for cervical cancer, our objective was to describe the actinic cytopathic effects. Our paper was based on a structured review including the period from June 2015 to April 2016, aiming at an exploratory-descriptive study. Bibliographic investigations were carried out through selection and analysis of articles, list of authors and keywords, selection of new articles focused on the analysis of bibliographic references to previously selected documents, as well as textbooks of recognized merit. The most incident actinic cytopathological alterations as described in the literature are: cellular gigantism, nuclear and cytoplasmic vacuolization, dyskeratosis, bi- and multinucleated (B/M cells, macro and multiple nucleoli, anisokaryosis, anisonucleolosis and nuclear pyknosis. To date, a protocol has not been established that can precisely differentiate the morphological characteristics between benign cells with actinic effects from recurrent malignant cells on post-radiotherapy smears.

  10. Assessing the Eventual Publication of Clinical Trial Abstracts Submitted to a Large Annual Oncology Meeting.

    Science.gov (United States)

    Massey, Paul R; Wang, Ruibin; Prasad, Vinay; Bates, Susan E; Fojo, Tito

    2016-03-01

    Despite the ethical imperative to publish clinical trials when human subjects are involved, such data frequently remain unpublished. The objectives were to tabulate the rate and ascertain factors associated with eventual publication of clinical trial results reported as abstracts in the Proceedings of the American Society of Clinical Oncology (American Society of Clinical Oncology). Abstracts describing clinical trials for patients with breast, lung, colorectal, ovarian, and prostate cancer from 2009 to 2011 were identified by using a comprehensive online database (http://meetinglibrary.asco.org/abstracts). Abstracts included reported results of a treatment or intervention assessed in a discrete, prospective clinical trial. Publication status at 4-6 years was determined by using a standardized search of PubMed. Primary outcomes were the rate of publication for abstracts of randomized and nonrandomized clinical trials. Secondary outcomes included factors influencing the publication of results. A total of 1,075 abstracts describing 378 randomized and 697 nonrandomized clinical trials were evaluated. Across all years, 75% of randomized and 54% of nonrandomized trials were published, with an overall publication rate of 61%. Sample size was a statistically significant predictor of publication for both randomized and nonrandomized trials (odds ratio [OR] per increase of 100 participants = 1.23 [1.11-1.36], p oncology trials are not published. The data show that 4-6 years after appearing as abstracts, 39% of oncology clinical trials remain unpublished. Larger sample size and advanced trial phase were associated with eventual publication; among randomized trials, an industry-affiliated author or a cooperative group increased likelihood of publication. Unfortunately, we found that, despite widespread recognition of the problem and the creation of central data repositories, timely publishing of oncology clinical trials results remains unsatisfactory. ©AlphaMed Press.

  11. SERUM VITAMIN B12, IRON AND FOLIC ACID DEFICIENCIES IN OBESE INDIVIDUALS SUBMITTED TO DIFFERENT BARIATRIC TECHNIQUES.

    Science.gov (United States)

    Silva, Rafaella de Andrade; Malta, Flávia Monteiro França; Correia, Maria Flora Ferreira Sampaio Carvalho; Burgos, Maria Goretti Pessoa de Araújo

    Different surgical techniques to combat obesity combine malabsorption with restrictive procedures and can lead to metabolic problems, such as micronutrient deficiencies. Assess vitamin B12, iron and folic acid deficiencies associated with the lifestyle of obese individuals having been submitted to different bariatric techniques. A retrospective analysis was performed using the electronic charts of patients submitted to bariatric surgery involving adjustable gastric banding and Roux-en-Y gastric bypass at the São João Hospital Center in the city of Porto, Portugal, between 2005 and 2010. The following data were collected: surgical technique, sex, age, marital status, serum concentrations of vitamin B12, iron and folic acid and postoperative lifestyle. A 5% significance level was used for the statistical analysis (pvitamina B12, ferro e ácido fólico e fatores associados ao estilo de vida de obesos submetidos a diferentes técnicas cirúrgicas. Análise retrospectiva dos prontuários eletrônicos de pacientes submetidos à cirurgia bariátrica pelas técnicas de banda gástrica ajustável e bypass gástrico em Y-de-Roux, no Centro Hospitalar de São João, E.P.E., Porto - Portugal, no período de 2005-2010. Foram coletadas: técnica cirúrgica, sexo, idade, estado civil, concentrações séricas de vitamina B12, ferro e ácido fólico e o estilo de vida no pós-operatório. Para análise estatística foi utilizado nível de significância de 5% (pvitamina B12 (16,9%) e do ácido fólico (4,5%). A ingestão de bebida alcoólica de leve-moderada, a adesão à dieta e o uso de polivitamínicos reduziu a frequência, mas não evitou a carência de micronutrientes. A deficiência de vitamina B12, ferro e ácido fólico foi observada durante o primeiro e o segundo anos após as duas técnicas avaliadas, sendo mais frequente nos pacientes submetidos ao bypass gástrico.

  12. Ozone Therapy on Rats Submitted to Subtotal Nephrectomy: Role of Antioxidant System

    Directory of Open Access Journals (Sweden)

    José Luis Calunga

    2005-01-01

    rectal administrations produced a delay in the advance of the disease, protecting the kidneys against vascular, hemorheological, and oxidative mechanisms. This behavior suggests ozone therapy has a protective effect on renal tissue by downregulation of the oxidative stress shown in CRF.

  13. Ozone Therapy on Rats Submitted to Subtotal Nephrectomy: Role of Antioxidant System

    Science.gov (United States)

    Calunga, José Luis; Zamora, Zullyt B.; Borrego, Aluet; del Río, Sarahí; Barber, Ernesto; Menéndez, Silvia; Hernández, Frank; Montero, Teresita; Taboada, Dunia

    2005-01-01

    administrations produced a delay in the advance of the disease, protecting the kidneys against vascular, hemorheological, and oxidative mechanisms. This behavior suggests ozone therapy has a protective effect on renal tissue by downregulation of the oxidative stress shown in CRF. PMID:16192672

  14. 20 CFR 1002.115 - Is the employee required to report to or submit a timely application for reemployment to his or...

    Science.gov (United States)

    2010-04-01

    ... submit a timely application for reemployment to his or her pre-service employer upon completing the... reemployment to his or her pre-service employer upon completing the period of service in the uniformed services... employer of his or her intent to return to the employment position by either reporting to work or...

  15. A Study on Evaluation of the Biology Projects Submitted to the TUBITAK Secondary Education Research Projects Contest from the Bursa Region

    Science.gov (United States)

    Zeren Özer, Dilek; Güngör, Sema Nur; Özkan, Muhlis

    2015-01-01

    This study evaluates, through the employment of scientific methods and techniques, a total of 107 Biology projects submitted by secondary education students to the Bursa Region Coordinatorship of TUBITAK (a region which encompasses the municipalities of Afyonkarahisar, Balikesir, Bilecik, Canakkale, Eskisehir, Kutahya, and Yalova). The projects…

  16. The Impact of Support Services on Students' Test Anxiety and/or Their Ability to Submit Assignments: A Focus on Vision Impairment and Intellectual Disability

    Science.gov (United States)

    Datta, Poulomee; Talukdar, Joy

    2017-01-01

    This study investigated the influence of the support services on the test anxiety of students and/or their ability to submit assignments in each of the two disability groups, those with vision impairment and those with intellectual disability, who were placed in specialist and mainstream educational settings in South Australia. Interviews were…

  17. 21 CFR 803.42 - If I am an importer, what information must I submit in my individual adverse event reports?

    Science.gov (United States)

    2010-04-01

    ... submit in my individual adverse event reports? 803.42 Section 803.42 Food and Drugs FOOD AND DRUG... individual adverse event reports? You must include the following information in your report, if the... of birth; (3) Patient gender; and (4) Patient weight. (b) Adverse event or product problem (Form...

  18. 21 CFR 803.32 - If I am a user facility, what information must I submit in my individual adverse event reports?

    Science.gov (United States)

    2010-04-01

    ... submit in my individual adverse event reports? 803.32 Section 803.32 Food and Drugs FOOD AND DRUG... individual adverse event reports? You must include the following information in your report, if reasonably...) Patient gender; and (4) Patient weight. (b) Adverse event or product problem (Form 3500A, Block B). You...

  19. 23 CFR Appendix B to Part 1240 - Procedures for Missing or Inadequate State-Submitted Information (Calendar Years 1996 and 1997)

    Science.gov (United States)

    2010-04-01

    ... Information (Calendar Years 1996 and 1997) B Appendix B to Part 1240 Highways NATIONAL HIGHWAY TRAFFIC SAFETY... 1240—Procedures for Missing or Inadequate State-Submitted Information (Calendar Years 1996 and 1997) A... years 1996 and 1997, State seat belt use rates for calendars year 1996 and 1997 will be estimated based...

  20. 40 CFR Table 18 to Subpart G of... - Information for Waste Management Units To Be Submitted With Notification of Compliance Status a,b

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Information for Waste Management Units... Subpart G of Part 63—Information for Waste Management Units To Be Submitted With Notification of Compliance Status a,b Waste management unit identification c Description d Wastewater stream(s) received or...

  1. Arachnids submitted as suspected brown recluse spiders (Araneae: Sicariidae): Loxosceles spiders are virtually restricted to their known distributions but are perceived to exist throughout the United States.

    Science.gov (United States)

    Vetter, Richard S

    2005-07-01

    An Internet offer was made to identify any spider in the United States perceived to be a brown recluse spider, Loxosceles reclusa Gertsch & Mulaik (Sicariidae). In total, 1,773 arachnids from 49 states represented three orders (Araneae, Solifugae, and Opiliones) and the identifiable spiders (Araneae) consisted of 38 families, 88 genera, and 158 recognizable species. Participants from states at least half within the known brown recluse distribution submitted Loxosceles spiders 32- 89% of the time, except Louisiana and Mississippi with no submissions. From 25 of 29 states completely or almost completely outside of the range of Loxosceles spiders, no recluse spiders were submitted. Only two discoveries of brown recluses and two of the worldwide tramp species Loxosceles rufescens (Dufour) were submitted from nonendemic Loxosceles areas. States on distribution margins of brown recluse or other native Loxosceles spiders were intermediate in their Loxosceles submissions. This study showed that 1) the general public perceives brown recluses to occur over wide-ranging areas of the United States; and 2) brown recluses are frequently submitted from endemic states and almost never from nonendemic states, and therefore are virtually limited to their known distributions. This study corroborates opinions that diagnosis of brown recluse spider bites is best restricted to areas historically supporting proven, widespread populations of Loxosceles spiders.

  2. How to Contribute to the Development of a Global Understanding of Corporate Governance? Reflections from Submitted and Published Articles in CGIR

    NARCIS (Netherlands)

    Zattoni, Alessandro; Van Ees, Hans

    Manuscript Type: Review Research Question/Issue: The article starts as a reflection on the criteria that articles submitted to CGIR should respect in order to pass the screening and referee procedures. Beyond that, the article explores the characteristics of all articles, and particularly of best

  3. 41 CFR 102-34.335 - How do I submit information to the General Services Administration (GSA) for the Federal Fleet...

    Science.gov (United States)

    2010-07-01

    ... (Continued) FEDERAL MANAGEMENT REGULATION PERSONAL PROPERTY 34-MOTOR VEHICLE MANAGEMENT Federal Fleet Report... Orders. In addition, the Office of Management and Budget (OMB) requires agency Fleet Managers and budget... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How do I submit...

  4. 30 CFR 285.700 - What reports must I submit to MMS before installing facilities described in my approved SAP, COP...

    Science.gov (United States)

    2010-07-01

    ... installing facilities described in my approved SAP, COP, or GAP? 285.700 Section 285.700 Mineral Resources... § 285.700 What reports must I submit to MMS before installing facilities described in my approved SAP... in your approved COP (§ 285.632(a)) and, when required by this part, your SAP (§ 285.614(b)) or GAP...

  5. 41 CFR 102-74.145 - What information must a Federal agency submit to GSA after the agency has identified a need for...

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What information must a... public building? 102-74.145 Section 102-74.145 Public Contracts and Property Management Federal Property... Facility Management Asset Services § 102-74.145 What information must a Federal agency submit to GSA after...

  6. Efficiency of five chemical protective clothing materials against nano and submicron aerosols when submitted to mechanical deformations.

    Science.gov (United States)

    Ben Salah, Mehdi; Hallé, Stéphane; Tuduri, Ludovic

    2016-01-01

    Due to their potential toxicity, the use of nanoparticles in the workplace is a growing concern. Some studies indicate that nanoparticles can penetrate the skin and lead to adverse health effects. Since chemical protective clothing is the last barrier to protect the skin, this study aims to better understand nanoparticle penetration behaviour in dermal protective clothing under mechanical deformation. For this purpose, five of the most common types of fabrics used in protective clothing, one woven and four nonwoven, were chosen and submitted to different simulated exposure conditions. They were tested against polydispersed NaCl aerosols having an electrical-mobility diameter between 14 and 400 nm. A bench-scale exposure setup and a sampling protocol was developed to measure the level of penetration of the aerosols through the material samples of disposable coveralls and lab coat, while subjecting them to mechanical deformations to simulate the conditions of usage in the workplace. Particle size distribution of the aerosol was determined upstream and downstream using a scanning mobility particle sizer (SMPS). The measured efficiencies demonstrated that the performances of nonwoven materials were similar. Three nonwovens had efficiencies above 99%, while the woven fabric was by far, the least effective. Moreover, the results established that mechanical deformations, as simulated for this study, did not have a significant effect on the fabrics' efficiencies.

  7. Oral Glutamine Is Superior Than Oral Glucose to Promote Glycemia Recovery in Mice Submitted to Insulin-Induced Hypoglycemia

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    Amanda Nunes Santiago

    2013-01-01

    Full Text Available The effect of the oral administration of blood glucose precursors on glycemia recovery and liver glucose production in fasted mice subjected to insulin-induced hypoglycemia (IIH was investigated. IIH was obtained with increasing doses (from 0.5 to 2.0 U·kg−1 of intraperitoneal regular insulin where glycemia was evaluated from 0 to 300 min after insulin injection. The dose of 1.0 U·kg−1 showed the best results, that is, a clear glycemia recovery phase without convulsions or deaths. Thus, this dose was used in all experiments. Afterwards, mice submitted to IIH received orally by gavage: saline (control group, glucose (100 mg·kg−1, glycerol (100 mg·kg−1, lactate (100 mg·kg−1, alanine (100 mg·kg−1, or glutamine (100 mg·kg−1. It was observed that glutamine was more effective in promoting glycemia recovery if compared with glucose, lactate, glycerol, or alanine. In agreement with these results, the best performance in terms of liver glucose production was obtained when glutamine was used as glucose precursors. These results open perspectives for clinical studies to investigate the impact of oral administration of gluconeogenic amino acids to promote glycemia recovery during hypoglycemia.

  8. Three-dimensional dental arch changes of patients submitted to orthodontic-surgical treatment for correction of Class II malocclusion

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    Adriano Porto Peixoto

    2014-08-01

    Full Text Available INTRODUCTION: This study assessed the three-dimensional changes in the dental arch of patients submitted to orthodontic-surgical treatment for correction of Class II malocclusions at three different periods. METHODS: Landmarks previously identified on upper and lower dental casts were digitized on a three-dimensional digitizer MicroScribe-3DX and stored in Excel worksheets in order to assess the width, length and depth of patient's dental arches. RESULTS: During orthodontic preparation, the maxillary and mandibular transverse dimensions measured at the premolar regions were increased and maintained throughout the follow-up period. Intercanine width was increased only in the upper arch during orthodontic preparation. Maxillary arch length was reduced during orthodontic finalization, only. Upper and lower arch depths were stable in the study periods. Differences between centroid and gingival changes suggested that upper and lower arch premolars buccaly proclined during the pre-surgical period. CONCLUSIONS: Maxillary and mandibular dental arches presented transverse expansion at premolar regions during preoperative orthodontic preparation, with a tendency towards buccal tipping. The transverse dimensions were not altered after surgery. No sagittal or vertical changes were observed during the follow-up periods.

  9. Validation of the Brazilian version of the Expanded Prostate Cancer Index Composite (EPIC for patients submitted to radical prostatectomy

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    Enaury Alves

    2013-06-01

    Full Text Available Objectives Validation of the Expanded Prostate Cancer Index Composite (EPIC questionnaire translated to Portuguese. This is an evaluation tool of the effects of treatment on quality of life of patients with prostate cancer. Materials and Methods In order to translate and validate, several recommended methodological techniques in the literature were included: initial translation, synthesis of translation, board committee review and back translation. Sample included 40 patients with localized prostate cancer submitted to surgical retropubic radical prostatectomy from 2008 to 2010. Results The internal consistency analysis of the scales of the questionnaire resulted in alpha Cronbach coefficients “very good” (> 0.9 and “good” (> 0.8 to 8 of 14 domains. The higher coefficients (0.94 were assigned to sexual score, subscales incontinence and sexual function. Post-operatory follow-up ranged from 3 to 35 months, median 18.7 months. Conclusions The Brazilian version of EPIC is reliable and valid, and is a useful tool to evaluate the impact of retropubic radical prostatectomy on quality of life of Brazilian patients with localized prostate cancer, in national and internationals studies.

  10. Analysis of expressed sequence tags from Musa acuminata ssp. burmannicoides, var. Calcutta 4 (AA) leaves submitted to temperature stresses.

    Science.gov (United States)

    Santos, C M R; Martins, N F; Hörberg, H M; de Almeida, E R P; Coelho, M C F; Togawa, R C; da Silva, F R; Caetano, A R; Miller, R N G; Souza, M T

    2005-05-01

    In order to discover genes expressed in leaves of Musa acuminata ssp. burmannicoides var. Calcutta 4 (AA), from plants submitted to temperature stress, we produced and characterized two full-length enriched cDNA libraries. Total RNA from plants subjected to temperatures ranging from 5 degrees C to 25 degrees C and from 25 degrees C to 45 degrees C was used to produce a COLD and a HOT cDNA library, respectively. We sequenced 1,440 clones from each library. Following quality analysis and vector trimming, we assembled 2,286 sequences from both libraries into 1,019 putative transcripts, consisting of 217 clusters and 802 singletons, which we denoted Musa acuminata assembled expressed sequence tagged (EST) sequences (MaAES). Of these MaAES, 22.87% showed no matches with existing sequences in public databases. A global analysis of the MaAES data set indicated that 10% of the sequenced cDNAs are present in both cDNA libraries, while 42% and 48% are present only in the COLD or in the HOT libraries, respectively. Annotation of the MaAES data set categorized them into 22 functional classes. Of the 2,286 high-quality sequences, 715 (31.28%) originated from full-length cDNA clones and resulted in a set of 149 genes.

  11. Hyperbaric oxygen in skeletal muscle of rats submitted to total acute left hindlimb ischemia: A research report.

    Science.gov (United States)

    da Silva, Luis Gustavo Campos; Dalio, Marcelo Bellini; Joviliano, Edwaldo Edner; Feres, Omar; Piccinato, Carlos Eli

    2015-01-01

    Determine the effect of hyperbaric oxygen treatment in skeletal muscle of rats submitted to total acute left hindlimb ischemia. An experimental study was designed using 48 Wistar rats divided into four groups (n = 12): Control; Ischemia (I)--total hindlimb ischemia for 270 minutes; Hyperbaric oxygen treatment during ischemia (HBO2)--total hindlimb ischemia for 270 minutes and hyperbaric oxygen during the first 90 minutes; Pre-treatment with hyperbaric oxygen (PHBO2)--90 minutes of hyperbaric oxygen treatment before total hindlimb ischemia for 270 minutes. Skeletal muscle injury was evaluated by measuring levels of aspartate aminotransferase (AST), lactate dehydrogenase (LDH), total creatine phosphokinase (CPK); muscular malondialdehyde (MDA), muscular glycogen, and serum ischemia-modified albumin (IMA). AST was significantly higher in I, HBO2 and PHBO2 compared with control (P = .001). There was no difference in LDH. CPK was significantly higher in I, HBO2 and PHBO2, compared with control (p = .014). MDA was significantly higher in PHBO2, compared with other groups (p = .042). Glycogen was significantly decreased in I, HBO2 and PHBO2, compared with control (p < .001). Hyperbaric oxygen treatment in acute total hindlimb ischemia exerted no protective effect on muscle injury, regardless of time of application. When applied prior to installation of total ischemia, hyperbaric oxygen treatment aggravated muscle injury.

  12. The number of articles submitted to the Journal of the Faculty of Medicine experienced a dramatic increase

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    Franklin Escobar-Córdoba

    2017-06-01

    Full Text Available The Journal of the Faculty of Medicine of Universidad Nacional de Colombia has undergone important changes in the past years; the amount of articles submitted for initiating the editorial process has increased, in the same manner as the amount of articles received in English language, and the rejection rate, which is now around 40%. The number of international authors has also grown, thus demonstrating that the publication has achieved greater visibility and recognition. In this context, the following articles have been selected for the first issue of Volume 69 of the Journal of the Faculty of Medicine: “Is parricide a stable phenomenon? An analysis of parricide offenders in a forensic hospital” (1 is a study written by an important group of Brazilian authors, who demonstrate their expertise in one of the crimes that causes most social upheaval due to its broad implications. Parricide immediately attracts attention as it is easily linked to the presence of a mental disorder, which is actually corroborated by this study, since it shows that most parricides are young adult males, who have a low level of education, are single, with no criminal history and schizophrenic; in addition, few cases show antisocial personality disorders.

  13. Degree of conversion and molecular weight of one denture base and three reline resins submitted to post-polymerization treatments

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    Vanessa Migliorini Urban

    2007-06-01

    Full Text Available The effect of post-polymerization treatments (MW-microwave irradiation and WB-water-bath on the degree of conversion (DC of three reline resins (Ufi Gel hard-U, Kooliner-K, and Tokuso Rebase Fast-T and one denture base resin (Lucitone 550-L, submitted to two polymerization cycles (LS-short and LL-long, was evaluated by using FT-Raman spectroscopy (n = 5. The molecular weight (Mw of the powder of all materials and of K polymerized specimens (control; MW; and WB; n = 3 was analyzed using GPC. DC data were analyzed using Kruskal-Wallis test (a = .05. For control specimens, there were no significant differences between U (68% and LL (77% and among LL, K (81%, and T (84%. LS (92% had the highest DC (P < 0.05. Only material K exhibited an increased DC after WB (P < 0.05. All powders had Mw from 4.0 x 10(5 to 6.5 x 10(5 and narrow Mw distributions (2.1 to 3.6. Polymerization and post-polymerization produced K specimens with Mw similar to that of K powder.

  14. Er:YAG laser evaluation of smear layer removal from flattened root canals submitted to rotary instrumentation

    Science.gov (United States)

    Heredia Seixas, Fabio; Brugnera, Aldo, Jr.; Gariba Silva, Ricardo; Capelli, Alexandre; Zanello Guerisoli, Danilo M.; Djalma Pecora, Jesus

    2003-06-01

    This study evaluated smear layer removal of 40 mesio-distal flattened root canals after rotary instrumentation. Teeth were divided into 4 goups: Group 1: 2.5% sodium hypochlorite was used as an irrigating solution; Group 2: instrumented as Group 1 followed by Er:YAG laser irradiation (140mJ input/10Hz, withdrawn at 2mm/s from the apical to the cervical region touching the buccal wall; the procedure was then repeated for the lingual wall); Group 3: instrumented as Group 1 and followed by Er:YAG laser irradiation (250mJ input/10Hz, in the same way as described for Group 2) and Group 4: instrumented as Group 1 and alternated with 17% EDTA. Teeth were then split longitudinally and prepared for examination under the scanning electron microscope. Scores from 1 to 4 were given to the fotomicrographs by three independent evaluators, and these data were submitted to statistical analysis. Teeth where alternated 17% EDTA was used (Group 4) showed less amount of smear layer, followed by the group irradiated with 250mJ input/10Hz (Group 3), the group irradiated with 140mJ input/10Hz(Group 2) and the group where only sodium hypochlorite was used (Group 1). The apical third presented more smear layer than the middle third (p<00.1)

  15. Nutritional value of Lemna valdiviana Phil (Araceae submitted to different concentrations of fertilization with excrement of birds

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    Graça Maria de Oliveira França

    2009-09-01

    Full Text Available The lemnaceas are aquatic plants with great potential for use as raw material in the production of fish feed because they have a high nutritional value. The objective of this study was to evaluate the chemical composition and nutritional quality of Lemna valdiviana submitted to different rates of fertilization with bird excrement. The experiment was conducted in a completely randomized design with three repetitions. The treatments were: Control (without fertilizer; T1 – 150g.m-3, T2 – 300g.m-3 and T3 – 450g.m-3 of fresh excrement, distributed in a single dose to fertilize the L. valdiviana. The dose that provided the best nutritional quality of L. valdiviana was 450g.m-3, with a crude protein content of 19.66% in the dry matter, a fiber content of 13.06%, and 0.26% of P, 1.63% of N, 0.37% of Na and 1.22% of Ca in the dry mass. The levels achieved in this study indicate that L. valdiviana may be considered a good quality of raw material to be used in other experiments as a nutritional supplement for fish diet.

  16. The effects of coconut oil supplementation on the body composition and lipid profile of rats submitted to physical exercise.

    Science.gov (United States)

    Resende, Nathália M; Félix, Henrique R; Soré, Murillo R; M M, Aníbal; Campos, Kleber E; Volpato, Gustavo T

    2016-05-13

    This study aims to verify the effects of coconut oil supplementation (COS) in the body composition and lipid profile of rats submitted to physical exercise. The animals (n=6 per group) were randomly assigned to: G1=Sedentary and Non-supplemented (Control Group), G2=Sedentary and Supplemented, G3=Exercised and Non-supplemented and G4=Exercised and Supplemented. The COS protocol used was 3 mL/Kg of body mass by gavage for 28 days. The physical exercise was the vertical jumping training for 28 days. It was determined the body mass parameters, Lee Index, blood glucose and lipid profile. The COS did not interfere with body mass, but the lean body mass was lower in G3 compared to G2. The final Lee Index classified G1 and G2 as obese (>30g/cm). The lipid profile showed total cholesterol was decreased in G3, LDL-c concentration was decreased in G2, triglycerides, VLDL-c and HDL-c concentrations were increased in G2 and G4 in relation to G1 and G3. The COS decreased LDL-c/HDL-c ratio. In conclusion, the COS associated or not to physical exercise worsen others lipid parameters, like triglycerides and VLDL-c level, showing the care with the use of lipid supplements.

  17. Performance of Chicks Submitted to Fasting Post-Hatching and with Maltodextrine Supplementing to Diet as Hydrating and Energetic Additive

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    CA Machado

    Full Text Available ABSTRACT This study aimed to evaluate the effect of maltodextrin on performance of chicks passed through four fasting periods. A completely randomized design was performed, consisting of three treatments (1 - control, 2 - 4% saccharose; 3-4% maltodextrin 20 and four fasting periods after hatching (0, 12, 24 and 36 hours with four replications, totaling 1920 birds of both sexes. The studied variables were: water intake in the first 12 hours, average food intake, average body weight and real feed conversion. Data was submitted to analysis of variance and means were compared with each other by Dunnett test at 5% significance. The use of additives and imposing of different fasting periods did not influence the performance at 42 days old. Therefore, fasted chicks consumed significantly more water. At 7 days old, chicks fasted showed higher body weight and higher feed intake, however, the viability did not suffer any influence, the weight remained higher after 21days with the fast imposition and there was no influence on other variables. There was no effect of fasting on broiler chiken's performance at 42 days old. The inclusion of sucrose and maltodextrin to drinking water stimulated the chick´s water intake and provided higher viability after seven days old.

  18. Factors impacting successfully competing for research funding: an analysis of applications submitted to the Plastic Surgery Foundation.

    Science.gov (United States)

    Hume, Keith M; Giladi, Aviram M; Chung, Kevin C

    2015-02-01

    Federal research funding is decreasing, forcing specialty organizations to have an increasingly important position in developing and fostering research. As the research and innovation arm of the American Society of Plastic Surgeons, The Plastic Surgery Foundation has a key role in supporting promising plastic surgery research. Understanding the grant review process and factors that contribute to funding well-written grant funding applications is essential for aspiring academic surgeons. All research grant applications submitted to The Plastic Surgery Foundation in 2012 and 2013 were evaluated. Each reviewer comment was assessed independently by two study team members and classified into key weakness categories. The chi-square test was used to compare results between funded and unfunded grants. Linear regression identified which critique elements corresponded to changes in scores, and logistic regression identified elements that predicted funding. The authors analyzed 1764 comments from 240 applications. Of these, 55 received funding. Funded grants had significantly fewer reviewer comments in four of five weakness categories. As expected, funded grants received better (lower) scores. Concerns in the categories of plan for execution and other elements/grantsmanship significantly affected score and odds of funding. Ensuring that a grant addresses all required elements is important for receiving a low reviewer score. Our study demonstrates that plan for execution and grantsmanship influence reviewer scoring more than others. Investigators must clearly address items associated with conducting their experiments and performing the analysis. Investigators must also give equal attention to elements of overall quality and completeness to optimize chances of funding.

  19. Physicochemical characteristics and sensory profile of honey samples from stingless bees (Apidae: Meliponinae submitted to a dehumidification process

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    Carlos A.L. Carvalho

    2009-03-01

    Full Text Available This study was conducted to evaluate the effect of a dehumidification process on the physicochemical and sensory characteristics of stingless-bee honey. Melipona scutellaris and M. quadrifasciata honey samples were submitted to a dehumidification process and to physicochemical (reducing sugars, apparent sucrose, moisture, diastatic activity, hydroxymethylfurfural, ash, pH, acidity, and electric conductivity and sensory evaluations (fluidity, color, aroma, crystallization,flavor,and acceptability. The results indicated that the dehumidification process does not interfere with honey quality and acceptability.Este estudo foi conduzido com o objetivo de avaliar o efeito do processo de desumidificação sobre as características físico-químicas e sensoriais do mel das abelhas sem ferrão. Amostras de méis de Melipona scutellaris e M. quadrifasciata foram submetidas ao processo de desumidificação, passando em seguida por avaliações físico-químicas (açúcares redutores, sacarose aparente, umidade, atividade diastásica, hidroximetilfurfural, cinzas, pH, acidez e condutividade elétrica e sensoriais (fluidez, cor, aroma, cristalização, sabor e aceitabilidade. Os resultados indicaram que o processo de desumidificação não interfere na qualidade e aceitabilidade do mel.

  20. Lectin receptors distribution in the surface membrane of Trypanosoma cruzi blood forms collected from mice submitted to specific treatment

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    Gilberto Fontes

    1991-09-01

    Full Text Available The author investigated the distribution of lectin receptors on Trypanosoma cruzi blood forms collected from mice inoculated with, respectively, the drug-resistant and drug-sensitive strains VL-10 and CL, and treated with the two standard active nitroheterocyclic compounds nifurtimox and benznidazole used for treatment of human Chagas' disease. Blood trypomastigotes purified in Fycoll-Hypaque were incubated with fluorescein-labelled lectins Con A, WGA, EE, WFA, TPA and PNA and then microscopically examined. Neither qualitative or quantitative differences in the fluorescence intensity could be detected between parasites from VL-10 and CL strains submitted or not to treatment. The results suggest that both strains do not differ in their surface membrane carbohydrate moieties. Moreover, the rapid clearance of blood forms the drug-sensitive strain in animals treated with singlo doses of both compounds is not likely to depend on membrane alterations expressed by changes in the carbohydrate components. furthermore, resistance or sensitivity to drugs is not apparently related to carbohydrate distribution on T. cruzi blood forms.

  1. Quality of life and self-esteem in patients submitted to surgical treatment of skin carcinomas: long-term results.

    Science.gov (United States)

    Maciel, Paula Curitiba; Veiga-Filho, Joel; Carvalho, Marcelo Prado; Fonseca, Fernando Elias Martins; Ferreira, Lydia Masako; Veiga, Daniela Francescato

    2014-01-01

    Cancer is a multifactorial disease and skin carcinomas are the most common type of cancer. Assessing quality of life and self-esteem outcomes in skin cancer patients is important because these are indicators of the results of the treatment, translating how patients face their lives and their personal relationships. To assess the late impact of the surgical treatment of head and/or neck skin carcinomas on quality of life and self-esteem of the patients. Fifty patients with head or neck skin carcinomas were enrolled. Their age ranged between 30 and 75 years, 27 were men and 23 were women. Patients were assessed with regard to quality of life and self-esteem, preoperatively and five years postoperatively. Validated instruments were used: the MOS 36-item Short-form Health Survey (SF-36) and the Rosenberg Self-esteem/EPM-UNIFESP Scale. The Wilcoxon signed-rank test was used for the statistical analysis. Twenty-two patients completed the five-year follow-up, 54.5% women and 45.5% men. Compared to the preoperative assessment, patients had an improvement in mental health (p=0.011) and in self-esteem (p=0.002). There was no statistical difference with regard to the other domains of the SF-36. Patients submitted to surgical treatment of skin carcinoma improved mental health and self-esteem in the late postsurgical testing.

  2. In vitro evaluation of human dental enamel surface roughness bleached with 35% carbamide peroxide and submitted to abrasive dentifrice brushing

    Directory of Open Access Journals (Sweden)

    Worschech Claudia Cia

    2003-01-01

    Full Text Available The aim of this in vitro study was to evaluate the surface roughness of human enamel bleached with 35% carbamide peroxide at different times and submitted to different superficial cleaning treatments: G1 - not brushed; G2 - brushed with fluoride abrasive dentifrice; G3 - brushed with a non-fluoride abrasive dentifrice; G4 - brushed without dentifrice. Sixty fragments of human molar teeth with 4 x 4 mm were obtained using a diamond disc. The specimens were polished with sandpaper and abrasive pastes. A perfilometer was used to measure roughness average (Ra values of the initial surface roughness and at each 7-day-interval after the beginning of treatment. The bleaching was performed on the surface of the fragments for 1 hour a week, and the surface cleaning treatment for 3 minutes daily. The samples were stored in individual receptacles with artificial saliva. Analysis of variance and the Tukey test revealed significant differences in surface roughness values for G2 and G3, which showed an increase in roughness over time; G1 and G4 showed no significant roughness differences. The bleaching with 35% carbamide peroxide did not alter the enamel surface roughness, but when the bleaching treatment was performed combined with brushing with abrasive dentifrices, there was a significant increase in roughness values.

  3. The effects of coconut oil supplementation on the body composition and lipid profile of rats submitted to physical exercise

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    NATHÁLIA M. RESENDE

    2016-06-01

    Full Text Available This study aims to verify the effects of coconut oil supplementation (COS in the body composition and lipid profile of rats submitted to physical exercise. The animals (n=6 per group were randomly assigned to: G1=Sedentary and Non-supplemented (Control Group, G2=Sedentary and Supplemented, G3=Exercised and Non-supplemented and G4=Exercised and Supplemented. The COS protocol used was 3 mL/Kg of body mass by gavage for 28 days. The physical exercise was the vertical jumping training for 28 days. It was determined the body mass parameters, Lee Index, blood glucose and lipid profile. The COS did not interfere with body mass, but the lean body mass was lower in G3 compared to G2. The final Lee Index classified G1 and G2 as obese (>30g/cm. The lipid profile showed total cholesterol was decreased in G3, LDL-c concentration was decreased in G2, triglycerides, VLDL-c and HDL-c concentrations were increased in G2 and G4 in relation to G1 and G3. The COS decreased LDL-c/HDL-c ratio. In conclusion, the COS associated or not to physical exercise worsen others lipid parameters, like triglycerides and VLDL-c level, showing the care with the use of lipid supplements.

  4. Pharyngeal Residue and Aspiration and the Relationship with Clinical/Nutritional Status of Patients with Oropharyngeal Dysphagia Submitted to Videofluoroscopy.

    Science.gov (United States)

    Oliveira, D L; Moreira, E A M; de Freitas, M B; Gonçalves, J de A; Furkim, A M; Clavé, P

    2017-01-01

    The aim of this study was to investigate the association between the videofluoroscopic (VFS) signs of impaired efficacy (pharyngeal residue) and safety (aspiration) swallowing and the clinical/nutritional status of patients with suspect of dysphagia. A cross-sectional study was conducted with patients submitted to videofluoroscopy. Data of 76 patients were analyzed between March 2011 and December 2014. The clinical history and VFS exams of patients ≥ 38 years were retrospectively analyzed. 88% patients presented Oropharyngeal Dysphagia (OD), 44.7% presented laryngeal penetration and 32% presented aspiration. 78% patients presented pharyngeal residue. Aspiration was associated with Head Neck Cancer (HNC) [Prevalence Ratio (PR): 2.27, p = 0.028] and cardiovascular disease (PR 1.96, p = 0.027). Underweight [Body Mass Index Underweight patients with OD had a higher prevalence rate of pharyngeal residue than those normally nourished (100% vs. 78%) (PR 1.34, p = 0.011). Pharyngeal residue was associated with male sex (PR 1.32, p = 0.040), neurodegenerative disease (PR 1.57, p = 0.021), stroke (PR 1.62, p = 0.009), cerebral palsy (PR 1.76, p = 0.006) and HNC (PR 1.73, p = 0.002). In the present study, neurologic diseases, HNC, male sex and underweight were associated to impaired swallowing efficacy. Underweight, independently of the other variables, was not associated with impaired swallowing safety.

  5. [Evaluation of changes made in the peri-operative care in patients submitted to elective abdominal surgery].

    Science.gov (United States)

    Walczewski, Mayra da Rosa Martins; Justino, Ariane Zanetta; Walczewski, Eduardo André Bracci; Coan, Tatiane

    2012-04-01

    To evaluate the results of the introduction of new measures to accelerate the postoperative recovery of patients undergoing elective abdominal surgery. We observed 162 patients and interviewed them on two distinct periods: the first between October to December 2009 (n = 81) comprised patients who underwent conventional perioperative monitoring (pre-intervention) and the second between March and May 2010 (n = 81), formed by a new group of patients, submitted to the new protocol of perioperative monitoring. Data collection in the two periods occurred without the knowledge of the professionals in the service. The variables were: indication for preoperative nutritional support, duration of fasting, post-operative volume of hydration, use of catheters and drains, length of stay and postoperative morbidity. when comparing the two periods we observed a decrease of 2.5 hours in the time of preoperative fasting (p = 0.0002) in the post-intervention group. As for the reintroduction of oral diet, there was no difference between the two periods (p = 0.0007). When considering the patients without postoperative complications, there was a significantly decreased length of stay (p = 0.001325). There was a reduction of approximately 50% in antibiotic use in the post-intervention group (p = 0.00001). The adoption of multidisciplinary perioperative measures is feasible within our reality, and although there was no statistically significant changes in the present study, it may improve morbidity and reduce length of stay in general surgery.

  6. Analysis of Dental Enamel Surface Submitted to Fruit Juice Plus Soymilk by Micro X-Ray Fluorescence: In Vitro Study

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    Janaína Salmos Brito

    2016-01-01

    Full Text Available Objective. This paper aimed to analyze the in vitro industrialized fruit juices effect plus soy to establish the erosive potential of these solutions. Materials and Methods. Seventy bovine incisors were selected after being evaluated under stereomicroscope. Their crowns were prepared and randomly divided into 7 groups, using microhardness with allocation criteria. The crowns were submitted to the fruit juice plus soy during 15 days, twice a day. The pH values, acid titration, and Knoop microhardness were recorded and the specimens were evaluated using X-ray microfluorescence (µXRF. Results. The pH average for all juices and after 3 days was significantly below the critical value for dental erosion. In average, the pH value decreases 14% comparing initial time and pH after 3 days. Comparing before and after, there was a 49% microhardness decrease measured in groups (p<0.05. Groups G1, G2, G5, and G6 are above this average. The analysis by μXRF showed a decrease of approximately 7% Ca and 4% P on bovine crowns surface. Florida (FL statistical analysis showed a statistically significant 1 difference between groups. Thus, a tooth chance to suffer demineralization due to industrialized fruit juices plus soy is real.

  7. Renal Development and Blood Pressure in Offspring from Dams Submitted to High-Sodium Intake during Pregnancy and Lactation

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    Terezila M. Coimbra

    2012-01-01

    Full Text Available Exposure to an adverse environment in utero appears to programme physiology and metabolism permanently, with long-term consequences for health of the fetus or offspring. It was observed that the offspring from dams submitted to high-sodium intake during pregnancy present disturbances in renal development and in blood pressure. These alterations were associated with lower plasma levels of angiotensin II (AII and changes in renal AII receptor I (AT1 and mitogen-activated protein kinase (MAPK expressions during post natal kidney development. Clinical and experimental evidence show that the renin-angiotensin system (RAS participates in renal development. Many effects of AII are mediated through MAPK pathways. Extracellular signal-regulated protein kinases (ERKs play a pivotal role in cellular proliferation and differentiation. In conclusion, high-sodium intake during pregnancy and lactation can provoke disturbances in renal development in offspring leading to functional and structural alterations that persist in adult life. These changes can be related at least in part with the decrease in RAS activity considering that this system has an important role in renal development.

  8. Tier2 Submit Software

    Science.gov (United States)

    Download this tool for Windows or Mac, which helps facilities prepare a Tier II electronic chemical inventory report. The data can also be exported into the CAMEOfm (Computer-Aided Management of Emergency Operations) emergency planning software.

  9. Qualidade de pequis fatiados e inteiros submetidos ao congelamento Quality of whole and sliced pequi submitted to freezing

    Directory of Open Access Journals (Sweden)

    Brígida Monteiro Vilas Boas

    2012-05-01

    Full Text Available O trabalho foi realizado com o objetivo de avaliar a qualidade de pequis inteiros e fatiados submetidos ao congelamento por ar forçado durante 12 meses de armazenamento. Os frutos foram selecionados, lavados, sanitizados, descascados, branqueados, resfriados, fatiados e mantidos inteiros, acondicionados em saco de polietileno de baixa densidade, congelados em túnel de congelamento com ar forçado por 6 horas (-18°C e armazenados em congelador doméstico a -18°C (±2°C, por 12 meses. A cada três meses, foram realizadas as seguintes análises: pH, acidez titulável, sólidos solúveis, firmeza, valores L*, a*, b*, h° e C*, carotenoides totais, β-caroteno, vitamina C, índice de peróxidos, coliformes a 35°C e a 45°C e pesquisa de Salmonella sp. O congelamento do pequi inteiro é mais efetivo em preservar os teores de sólidos solúveis e vitamina C e os valores L* e b* quando comparado com o do pequi fatiado. O tempo de armazenamento de 12 meses determina redução nos valores a*, b*, C* e de firmeza e nos teores de sólidos solúveis, carotenoides totais, β-caroteno e vitamina C em pequi congelado, independentemente do corte usado. O pequi congelado não sofre o processo de rancificação oxidativa nem alterações no pH, nos teores de acidez titulável e na tonalidade de cor (h°. Pequis congelados, na forma inteira e fatiada, são considerados seguros microbiologicamente durante 12 meses de armazenamento, não oferecendo riscos à saúde dos consumidores, desde que obedecidas à cadeia de frio e às boas práticas de fabricação.This research was carried out aiming to evaluate the quality of pequi fruit (whole and sliced after forced-air freezing storage during 12 months. The fruits were submitted to treatments as follows: selecting, washing, sanitizing, peeling, blanching, cooling, and slicing or not. After that, the fruits were storage using low density polyethylene bags and submitted to forced-air freezing (-18°C for 6 hours and

  10. Modeling of tri-chloro-fluoro-methane hydrate formation in a w/o emulsion submitted to steady cooling

    Energy Technology Data Exchange (ETDEWEB)

    Avendano-Gomez, Juan Ramon; Limas-Ballesteros, Roberto [Laboratorio de Investigacion en Ingenieria Quimica Ambiental, SEPI-ESIQIE, Instituto Politecnico Nacional, Unidad Profesional Adolfo Lopez Mateos, Zacatenco, Edificio 8, 3. piso 07738, Mexico DF (Mexico); Garcia-Sanchez, Fernando [Laboratorio de Termodinamica, Programa de Ingenieria Molecular, Instituto Mexicano del Petroleo, Eje Central Lazaro Cardenas 152, 07730 Mexico DF (Mexico)

    2006-05-15

    The aim of this work is to study the modeling of the thermal evolution inside an hydrate forming system which is submitted to an imposed steady cooling. The study system is a w/o emulsion where the formulation considers the CCl{sub 3}F as the hydrate forming molecule dissolved in the oil phase. The hydrate formation occurs in the aqueous phase of the emulsion, i.e. in the dispersed phase. The model equation is based on the resolution of the continuity equation in terms of a heat balance for the dispersed phase. The crystallization of the CCl{sub 3}F hydrate occurs at supercooling conditions (T{sub c}

  11. Analysis of the ecotoxicity data submitted within the framework of the REACH Regulation. Part 3. Experimental sediment toxicity assays.

    Science.gov (United States)

    Cesnaitis, Romanas; Sobanska, Marta A; Versonnen, Bram; Sobanski, Tomasz; Bonnomet, Vincent; Tarazona, Jose V; De Coen, Wim

    2014-03-15

    For the first REACH registration deadline, companies have submitted registrations with relevant hazard and exposure information for substances at the highest tonnage level (above 1000 tonnes per year). At this tonnage level, information on the long-term toxicity of a substance to sediment organisms is required. There are a number of available test guidelines developed and accepted by various national/international organisations, which can be used to investigate long-term toxicity to sediment organisms. However instead of testing, registrants may also use other options to address toxicity to sediment organisms, e.g. weight of evidence approach, grouping of substances and read-across approaches, as well as substance-tailored exposure-driven testing. The current analysis of the data provided in ECHA database focuses on the test methods applied and the test organisms used in the experimental studies to assess long-term toxicity to sediment organisms. The main guidelines used for the testing of substances registered under REACH are the OECD guidelines and OSPAR Protocols on Methods for the Testing of Chemicals used in the Offshore Oil Industry: "Part A: A Sediment Bioassay using an Amphipod Corophium sp." explaining why one of the mostly used test organisms is the marine amphipod Corophium sp. In total, testing results with at least 40 species from seven phyla are provided in the database. However, it can be concluded that the ECHA database does not contain a high enough number of available experimental data on toxicity to sediment organisms for it to be used extensively by the scientific community (e.g. for development of non-testing methods to predict hazards to sediment organisms). © 2013.

  12. [Evaluation of grip strength in normal and obese Wistar rats submitted to swimming with overload after median nerve compression].

    Science.gov (United States)

    Coradinia, Josinéia Gresele; Kakihata, Camila Mayumi Martin; Kunz, Regina Inês; Errero, Tatiane Kamada; Bonfleur, Maria Lúcia; Bertolini, Gladson Ricardo Flor

    2015-01-01

    To verify the functionality through muscle grip strength in animals with obesity induced by monosodium glutamate (MSG) and in control animals, which suffered compression of the right median nerve, and treated with swimming with overload. During the first five days of life, neonatal Wistar rats received subcutaneous injections of MSG. The control group received a hypertonic saline solution. Forty-eight rats were divided into six groups: G1 (control); G2 (control + injury); G3 (control + injury + swimming); G4 (obese); G5 (obese + injury); G6 (obese + injury + swimming). The animals in groups G2, G3, G5 and G6 were submitted to compression of the median nerve and G3 and G6 groups were treated, after injury, with swimming exercise with load for three weeks. The swimming exercise had a progressive duration, according to the week, of 20, 30 and 40minutes. Muscle strength was assessed using a grip strength meter preoperatively and on the 3rd, 7th, 14th and 21st days after surgery. The results were expressed and analyzed using descriptive and inferential statistics. When the grip strength was compared among assessments regardless of group, in the second assessment the animals exhibited lower grip strength. G1 and G4 groups had greater grip strength, compared to G2, G3, G4 and G6. The swimming exercise with overload has not been effective in promoting improvement in muscle grip strength after compression injury of the right median nerve in control and in obese-MSG rats. Copyright © 2013 Elsevier Editora Ltda. All rights reserved.

  13. Evaluation of the micro-mechanical strength of resin bonded-dentin interfaces submitted to short-term degradation strategies.

    Science.gov (United States)

    Feitosa, Victor P; Sauro, Salvatore; Watson, Timothy F; Correr, Américo B; Osorio, Raquel; Toledano, Manuel; Correr-Sobrinho, Lourenço; Sinhoreti, Mário Alexandre C

    2012-11-01

    The aim of this study was to evaluate the microtensile bond strength (μTBS) and confocal micropermeability of resin bonded-dentin specimens created using two representative two-step/self-etch adhesives submitted to short-term period degradation strategies such as simulated pulpal pressure, thermo- or mechanical-cycling challenges. Clearfil SE Bond (CSE) and Silorane adhesive (SIL) were bonded to flat deep dentin from seventy extracted human molars and light-cured for 10 s. Composite build-ups were constructed using with Filtek Z350 XT and Filtek P90 respectively. The specimens of each adhesive group were subjected to three different accelerated aging methods: (1) thermo-cycling challenge (5000 cycles); (2) mechanical-cycling load (200,000 cycles); (3) experiment and (4) conventional method for simulated pulpal pressure (20 cm H₂O). Control resin-bonded specimens were stored in distilled water for 24 h. μTBS and confocal microscopy (CLSM) micropermeability evaluation were performed and the results were analyzed using Two-way ANOVA and Tukey's tests (α=0.05). The CLSM evaluation revealed micro-cracks within the Silorane-bonded dentin subsequent to mechanical-cycling load, whereas, the simulated pulpal pressure induced evident micropermeability in both bonding agents. Mechanical loading provides discernible bonding degradation in a short-term period in resin-bonded dentin created using two-step/self-etch adhesives. However, simulated pulpal pressure may reduce the sealing ability of self-etch adhesives causing greater water uptake within the resin-dentin interface. Copyright © 2012 Elsevier Ltd. All rights reserved.

  14. Prophylaxis with nasal decolonization in patients submitted to total knee and hip arthroplasty: systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    David Sadigursky

    Full Text Available ABSTRACT Despite the evolution of the total knee and hip arthroplasty surgery, high postoperative complication rates in the short and long term still persist. Infection is one of the most challenging complications; due to its gravity and treatment difficulties, prophylaxis protocols have been created to decrease its incidence. The objective of this study was to evaluate the impact of the prophylaxis protocol for methicillin-resistant Staphylococcus aureus decolonization of the nares in patients previously identified by swab cultures, who were to be submitted to a total joint arthroplasty. A systematic review with meta-analysis was conducted, following the PRISMA-2015 protocol, using the descriptors: “arthroplasty” and “nasal decolonization,” or “joint arthroplasty” and “decolonization,” or “joint arthroplasty” and “nasal decolonization,” for final selection of four observational studies from 79 references identified. This study included a total sample of 10,179 patients, divided in two groups: the control group (4788 patients and intervention group (5391 patients. It was observed that the intervention group, in which prophylaxis with nasal decolonization was used, 59 (1.09% of the patients developed a surgical site infection, while in the control group there were 86 cases of surgical site infection (1.79%. This trend repeated itself in all articles, showing no publication biases, forming a homogeneous sample. The use of a prophylaxis protocol for decolonization of methicillin-resistant Staphylococcus aureus, reduced surgical site infection cases by approximately 39%.

  15. Acute Changes in Creatine Kinase Serum Levels in Adults Submitted a Static Stretching and Maximal Strength Test

    Directory of Open Access Journals (Sweden)

    M.G. Bara Filho

    2008-01-01

    Full Text Available Strength and flexibility are common components of a training program and their maximal values are obtained through specific tests. However, little information about the damage effect of these training procedures in a skeletal muscle is known. Objective: To verify a serum CK changes 24 h after a sub maximal stretching routine and after the static flexibility and maximal strength tests. Methods: the sample was composed by 14 subjects (man and women, 28 ± 6 yr. physical education students. The volunteers were divided in a control group (CG and experimental group (EG that was submitted in a stretching routine (EG-ST, in a maximal flexibility static test (EG-FLEX and in 1-RM test (EG-1-RM, with one week interval among tests. The anthropometrics characteristics were obtained by digital scale with stadiometer (Filizola, São Paulo, Brasil, 2002. The blood samples were obtained using the IFCC method with reference values 26-155 U/L. The De Lorme and Watkins technique was used to access maximal maximal strength through bench press and leg press. The maximal flexibility test consisted in three 20 seconds sets until the point of maximal discomfort. The stretching was done in normal movement amplitude during 6 secons. Results: The basal and post 24 h CK values in CG and EG (ST; Flex and 1 RM were respectively 195,0 ± 129,5 vs. 202,1 ± 124,2; 213,3 ± 133,2 vs. 174,7 ± 115,8; 213,3 ± 133,2 vs. 226,6 ± 126,7 e 213,3 ± 133,2 vs. 275,9 ± 157,2. It was only observed a significant difference (p = 0,02 in the pre and post values inGE-1RM. Conclusion: only maximal strength dynamic exercise was capable to cause skeletal muscle damage.

  16. Spreading depression is facilitated in adult rats previously submitted to short episodes of malnutrition during the lactation period

    Directory of Open Access Journals (Sweden)

    A.P. Rocha-de-Melo

    1997-05-01

    Full Text Available Lactating rat dams were submitted to short episodes (1, 2 or 3 weeks of nutritional restriction by receiving the "regional basic diet" (RBD, with 8% protein of low-income human populations of Northeast Brazil. Their pups were then studied regarding the developmental effects on body and brain weights. When the rats reached adulthood, cortical susceptibility to the phenomenon of spreading depression (SD was evaluated by performing electrophysiological recordings on the surface of the cerebral cortex. SD was elicited at 20-min intervals by applying 2% KCl for 1 min to a site on the frontal cortex and its occurrence was monitored at 2 sites in the parietal region by recording the electrocorticogram and the slow potential change of SD. When compared to control rats fed a commercial diet with 23% protein, early malnourished rats showed deficits in body and brain weights (10% to 60% and 3% to 15%, respectively, as well as increases in velocity of SD propagation (10% to 20%. These effects were directly related to the duration of maternal dietary restriction, with pups malnourished for 2 or 3 weeks presenting more intense weight and SD changes than those malnourished for 1 week. The effects of 1-week restrictions on SD were less evident in the pups malnourished during the second week of lactation and were more evident in pups receiving the RBD during the third week. The results indicate that short episodes of early malnutrition during the suckling period can affect body and brain development, as well as the cortical susceptibility to SD during adulthood. The data also suggest that the third week of lactation is the period during which the brain is most sensitive to malnutrition, concerning the effects on SD

  17. Endometrium evaluation with high-field (3-Tesla) magnetic resonance imaging in patients submitted to uterine leiomyoma embolization

    Energy Technology Data Exchange (ETDEWEB)

    Jacobs, Monica Amadio Piazza [Post-graduation Program in Abdominal Imaging, Hospital Israelita Albert Einstein, São Paulo, SP (Brazil); Nasser, Felipe [Intervention Radiology Department, Hospital Israelita Albert Einstein, São Paulo, SP (Brazil); Zlotnik, Eduardo; Messina, Marcos de Lorenzo [Gynecology and Obstetrics Department, Hospital Israelita Albert Einstein, São Paulo, SP (Brazil); Baroni, Ronaldo Hueb [Magnetic Resonance Unit, Imaging Department, Hospital Israelita Albert Einstein, São Paulo, SP (Brazil)

    2013-07-01

    To evaluate the endometrial alterations related to embolization of uterine arteries for the treatment of symptomatic uterine leiomyomatosis (pelvic pain and/or uterine bleeding) by means of high-field (3-Tesla) magnetic resonance. This is a longitudinal and prospective study that included 94 patients with a clinical and imaging diagnosis of symptomatic uterine leiomyomatosis, all of them treated by embolization of the uterine arteries. The patients were submitted to evaluations by high-field magnetic resonance of the pelvis before and 6 months after the procedure. Specific evaluations were made of the endometrium on the T2-weighted sequences, and on the T1-weighted sequences before and after the intravenous dynamic infusion of the paramagnetic contrast. In face of these measures, statistical analyses were performed using Student's t test for comparison of the results obtained before and after the procedure. An average increase of 20.9% was noted in the endometrial signal on T2-weighted images obtained after the uterine artery embolization procedure when compared to the pre-procedure evaluation (p=0.0004). In the images obtained with the intravenous infusion of paramagnetic contrast, an average increase of 18.7% was noted in the post-embolization intensity of the endometrial signal, compared to the pre-embolization measure (p<0.035). After embolization of the uterine arteries, there was a significant increase of the endometrial signal on the T2-weighted images and on the post-contrast images, inferring possible edema and increased endometrial flow. Future studies are needed to assess the clinical impact of these findings.

  18. Effect of chemical disinfectants on the transverse strength of heat-polymerized acrylic resins submitted to mechanical and chemical polishing.

    Science.gov (United States)

    Orsi, Iara Augusta; Andrade, Vanessa Gomes

    2004-10-01

    Immersion in chemical solutions used for cleansing and disinfecting prostheses can decrease the strength of denture base resins, making them more prone to fracture during use. The purpose of this study was to assess the effect of immersion in different chemical disinfectants for varying time periods on the transverse strength of 3 mechanically or chemically polished heat-polymerized acrylic resins. A total of 630 rectangular specimens (65 x 10 x 3 mm), 210 per resin (Classico, Lucitone 550, and QC-20), were fabricated. One side of each specimen was not polished and the other was either mechanically (n=300) or chemically (n=300) polished, and immersed for 10, 20, 30, 45, or 60 minutes in either 1%, 2.5%, or 5.25% sodium hypochlorite or 2% glutaraldehyde. Mechanically polished (n=15) and chemically polished (n=15) control specimens were immersed only in distilled water. The transverse strength (N/mm 2 ) was tested for failure in a universal testing machine, at a crosshead speed of 5 mm/min. Data were statistically analyzed using 2-way ANOVA and Student t test. Multiple comparisons were performed using Tukey and Scheffe tests (alpha=.05). There was significant difference (P resins. No significant differences were observed between resins submitted to both types of polishing or between different immersion periods (10 to 60 minutes), disinfectants, or interaction. Lucitone 550 resin presented the greatest transverse strength values with both types of polishing. Among the mechanically and chemically polished specimens, transverse strength was not affected after immersion in the disinfectants for the immersion periods tested (10 to 60 minutes). Chemically polished control and experimental (immersed in all solutions) QC-20 specimens showed significant differences in transverse strength values.

  19. Antimicrobial susceptibility of bacteria isolated from neonatal foal samples submitted to a New Zealand veterinary pathology laboratory (2004 to 2013).

    Science.gov (United States)

    Toombs-Ruane, L J; Riley, C B; Kendall, A T; Hill, K E; Benschop, J; Rosanowski, S M

    2016-03-01

    To describe antimicrobial susceptibility, and identify antimicrobial resistance (AMR), in bacteria isolated from New Zealand foals. A database search was performed of submissions to a veterinary pathology laboratory between April 2004 and December 2013 for bacterial culture of samples from foals foals were examined, and 127 bacterial isolates were cultured from 64 (63%) foals. Of the 127 isolates, 32 (25%) were Streptococcus spp., 30 (24%) were Staphylococcus spp., 12 (10%) were Enterococcus spp. and 26 (21%) were Escherichia coli. Of 83 Gram-positive isolates, 57 (69%) were susceptible to penicillin. Over all isolates, 92/126 (73%) were susceptible to gentamicin and 117/126 (93%) to enrofloxacin; 62/82 (76%) of Gram-positive, and 22/42 (52%) of Gram-negative bacteria were susceptible to ceftiofur; 53/81 (65%) of Gram-positive, and 23/44 (52%) of Gram-negative bacteria were susceptible to tetracycline; 59/82 (72%) of Gram-positive, and 23/44 (43%) of Gram-negative bacteria were susceptible to trimethoprim-sulfonamide. Of 126 isolates, 33 (26%) had MDR; >1 isolate with MDR was cultured from 24/64 (38%) foals, and ≥2 isolates with MDR were recovered from 8/64 (13%) foals. Multi-drug resistance, including resistance to commonly used antimicrobials, was found in bacterial isolates from foals in New Zealand. The results of this study are of concern from a treatment perspective as they indicate a potential for antimicrobial treatment failure. For future surveillance of AMR and the creation of national guidelines, it is important to record more data on samples submitted for bacterial culture.

  20. Compressibilidade de um Argissolo Amarelo distrocoeso submetido a diferentes manejos Compressibility of an Ultisol submitted to different managements

    Directory of Open Access Journals (Sweden)

    Veronildo S. Oliveira

    2011-05-01

    Full Text Available O objetivo deste trabalho foi avaliar a compressibilidade de um Argissolo Amarelo distrocoeso submetido a diferentes sistemas de manejo sob cultivo de cana-de-açúcar. O experimento foi realizado em áreas da Usina Triunfo Industrial, AL, onde se avaliaram os manejos: MA - mata nativa; MSI - manejo sem irrigação; MCI - manejo com irrigação e MCV - manejo com fertirrigação (vinhaça. Todas as áreas estudadas, exceto no MA, vêm utilizando o preparo convencional do solo com uso de grades pesadas. As amostras de solo foram coletadas nas profundidades de 0-20 e 20-40 cm. Trincheiras foram abertas nas quatro áreas de manejo em estudo, quando amostras de solo indeformadas foram retiradas com auxílio de aneis metálicos de 6,4 cm diâmetro e 2,5 cm de altura em cada profundidade. Após coletadas, as amostras foram saturadas e submetidas a sucções de 0,1 a 10 kPa; 50, 500 e 1500 kPa, levadas à prensa mecânica e realizado o ensaio de compressibilidade. A partir dos dados obtidos determinou-se a tensão de preconsolidação (σp das diversas amostras ensaiadas, cujos resultados foram submetidos à análise de regressão para a variável tensão de preconsolidação, em função da sucção matricial do solo. Em todos os manejos, a profundidade de 0-20 cm mostrou ser a mais susceptível à compactação em relação à profundidade de 20-40 cm; o manejo MCV alterou o comportamento compressivo do solo em ambas as profundidades (0-20 e 20-40 cm e a capacidade de suporte do solo foi maior em todos os manejos, nas camadas de 20-40 cm.The objective of this paper was to evaluate the compressibility of an Ultisol submitted to different managements of sugarcane cultivation. The investigation was carried out at Triunfo Mill, in the State of Alagoas, Brazil. The testing area was composed by four distinct sub-areas: a preserved forest (NF, an area without irrigation (MWOI, an irrigated area (MWI, and an area with vinasse (MWV. All investigated areas

  1. Effects of supplementation with L-glutamine and L-alanine in the body composition of rats submitted to resistance exercise

    Directory of Open Access Journals (Sweden)

    Audrey Yule Coqueiro

    Full Text Available Abstract We investigated the effects of glutamine and alanine supplementation on body composition of rats submitted to resistance exercise. Wistar rats were submitted to eight-week of resistance exercise, which consisted of climbing a ladder with progressive loads (25–100% of body weight. In the last 21 days of training, animals were supplemented with L-glutamine and L-alanine, as a dipeptide or in their free form (DIP, GLN + ALA and ALA groups, or water (SED and CTRL groups. RE attenuated body weight gain and lipid contents of CTRL group (p < 0.05 vs. SED and DIP supplementation promoted an increase in tibialis muscle weight, as well as in protein content (p < 0.05 vs. CTRL. Taken together, our data indicated that resistance exercise improves body composition and dipeptide potentiated the muscle hypertrophic effect.

  2. Nestin down-regulation of cortical radial glia is delayed in rats submitted to recurrent status epilepticus during early postnatal life

    OpenAIRE

    Carla Alessandra Scorza; Ricardo Mario Arida; Fulvio Alexandre Scorza; Esper Abrão Cavalheiro; Maria da Graça Naffah-Mazzacoratti

    2009-01-01

    OBJECTIVE: Nestin is temporarily expressed in several tissues during development and it is replaced by other protein types during cell differentiation process. This unique property allows distinguishing between undifferentiated and differentiated cells. This study was delineated to analyze the temporal pattern of nestin expression in cortical radial glial cells of rats during normal development and of rats submitted to recurrent status epilepticus (SE) in early postnatal life (P). METHOD: Exp...

  3. "Will steroids kill me if I use them once?" A qualitative analysis of inquiries submitted to the Danish anti-doping authorities

    OpenAIRE

    Christiansen, Ask Vest; Bojsen-Møller, Jens

    2012-01-01

    Background: The Danish strategy for fighting the use of anabolic androgenic steroids in fitness centres is likely the most comprehensive of its sort in the world. It is instituted in the national anti doping organisation, Anti Doping Denmark (ADD), and consists of doping controls, educational campaigns, and anonymous counselling through a web-based email service. Aim and method: Inquiries that were submitted to ADD's web-based counselling service over an 18 month period were explored with the...

  4. Evaluation of phenotypic parameters of the mononuclear peripheral blood cells through flow cytometry from dogs submitted to irradiation of head and neck

    Energy Technology Data Exchange (ETDEWEB)

    Toledo, Janine Muniz; Siqueira, Savio Lana; Campos, Tarcisio P. Ribeiro; Valenca, Patricia de Lima Falcao [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Programa de Pos-Graduacao em Ciencias e Tecnicas Nucleares]. E-mails: janine.toledo@gmail.com; savio.siqueira@ig.com.br; campos@nuclear.ufmg.br; patricia.falcao@yahoo.com.br

    2007-07-01

    The present paper addresses the investigation of the phenotypic parameters applying stimulation markers and cell immunosuppression markers in an animal model, through a flux cytometer, with the goal of looking for a future monitoring of the immunologic response of patients submitted to radiotherapy. Five dogs were submitted to low dose radiation, 2, 4 and 6 Gy at a protocol of head and neck. Samples of peripheral blood (PBMC) were collected before and after irradiation, and 2, 18h and 30d. Such samples were separated and were submitted to surface markers with monoclonal antibody anti-CD5, anti-CD4, anti-IgM, anti- CD14, anti-MHCII, anti-CTLA-4 and anti-IL-2R. The PBMCs were evaluated by flow cytometry. The following alterations were observed: reduction of the T-cell in circulation (CD5) and of the subpopulation CD4, reduction of the stimulation receptor and cellular interaction (MHC2) and from IL-2R, increasing of the expression CTLA-4. It was proved that the peripheral circulated cells during an in locus irradiation are morphological modified and therefore has its function redefined. Such results show the relevance of knowing the personal immune response of each patient through the investigation of the phenotype patter of their peripheral cell lineage. The quality of life of the patient can be improved and irradiation protocols may be altering in according to the personal immune response picture. (author)

  5. Contribution of industry funded post-marketing studies to drug safety: survey of notifications submitted to regulatory agencies

    Science.gov (United States)

    Prugger, Christof; Doshi, Peter; Ostrowski, Kerstin; Witte, Thomas; Hüsgen, Dieter; Keil, Ulrich

    2017-01-01

    Objectives To investigate the practice of post-marketing studies in Germany during a three year period and to evaluate whether these trials meet the aims specified in the German Medicinal Products Act. Design Survey of notifications submitted to German regulatory agencies before post-marketing studies were carried out, 2008-10. Setting Notifications obtained through freedom of information requests to the three authorities responsible for registering post-marketing studies in Germany. Main outcome measures Descriptive statistics of post-marketing studies, including the products under study, intended number of patients, intended number of participating physicians, proposed remunerations, study plan and protocol, and availability of associated scientific publications and reports on adverse drug reactions. Results Information was obtained from 558 studies, with a median of 600 (mean 2331, range 2-75 000) patients and 63 (270, 0-7000) participating physicians per study. The median remuneration to physicians per patient was €200 (€441, €0-€7280) (£170, £0-£6200; $215, $0-$7820), with a total remuneration cost of more than €217m for 558 studies registered over the three year period. The median remuneration per participating physician per study was €2000 (mean €19 424), ranging from €0 to €2 080 000. There was a broad range of drugs and non-drug products, of which only a third represented recently approved drugs. In many notifications, data, information, and results were, by contract, strictly confidential and the sole property of the respective sponsor. No single adverse drug reaction report could be identified from any of the 558 post-marketing studies. Less than 1% of studies could be verified as published in scientific journals. Conclusions Post-marketing studies are not improving drug safety surveillance. Sample sizes are generally too small to allow the detection of rare adverse drug reactions, and many participating physicians are

  6. POSTOPERATIVE EFFECT OF PHYSICAL THERAPY RELATED TO FUNCTIONAL CAPACITY AND RESPIRATORY MUSCLE STRENGTH IN PATIENTS SUBMITTED TO BARIATRIC SURGERY.

    Science.gov (United States)

    Oliveira, Josélia Jucirema Jarschel de; Freitas, Alexandre Coutinho Teixeira de; Almeida, Andréa Adriana de

    Respiratory physiotherapy plays an important role preventing complications in bariatric surgery. To assess the effects of out-patient physiotherapy during post-operative period through respiratory pressures and functional capacity in individuals submitted to bariatric surgery. A prospective longitudinal and controlled study was done in adults with body mass index (BMI) equal or greater than 40 kg/m², who have been submitted to bariatric surgery. They were divided into two groups: intervention-group, who performed out-patient physiotherapy twice a week, from thirty to sixty days after surgery; and the control-group, who only followed home instructions. Both groups were evaluated before surgery and sixty days after surgery through manovacuometry, six-minute walk test and the Borg Scale of perceived exertion. Twenty participants were included the intervention-group and twenty-three in the control-group. Both groups had significant and similar weight loss after surgery. The manovacuometry presented no differences comparing pre- and post-surgery and in the comparison between the groups. The result of the six-minute walk test for the intervention-group increased by 10.1% in the post-operative period in relation to pre-. The Borg scale of perceived exertion in the intervention-group in pre-surgery decreased by 13.5% in the post-surgery compared to pre-surgery. In the control-group there was no difference comparing pre- and post-operative values, as in the comparison with the intervention-group. The low-intensity exercise program, carried out between the 30th and the 60th day after bariatric surgery provided better functional capacity; did not change respiratory muscle strength; and improved the perceived exertion rate. A fisioterapia respiratória tem papel importante na prevenção das complicações da cirurgia bariátrica. Avaliar os efeitos da fisioterapia ambulatorial no pós-operatório através das pressões respiratórias e da capacidade funcional dos indiv

  7. Manifestações bucais em pacientes submetidos à quimioterapia Buccal manifestations in patients submitted to chemotherapy

    Directory of Open Access Journals (Sweden)

    Fernando Luiz Hespanhol

    2010-06-01

    Full Text Available Em decorrência da quimioterapia, alterações na cavidade oral podem ser observadas e levar a complicações sistêmicas importantes, podendo aumentar o tempo de internação hospitalar, os custos do tratamento e afetar diretamente a qualidade de vida dos pacientes. Este trabalho teve como objetivo realizar uma pesquisa em um hospital de oncologia da cidade de Juiz de Fora (MG, sendo realizado através de coleta de dados nos prontuários de pacientes que estiveram em tratamento oncológico, onde foram avaliadas as prevalências das manifestações orais em relação ao sexo, idade e tipo de tumor. Verificou-se que a mucosite foi a manifestação mais incidente em ambos os sexos em todas as faixas etárias (15,5%. A xerostomia e as demais lesões, como candidíase e lesões aftosas, também estiveram presentes. É possível melhorar a qualidade de vida antes, durante e após as terapias antineoplásicas através de um protocolo de atendimento odontológico que inclua medidas de condicionamento do meio bucal prévia à quimioterapia, como profilaxia, remoção de cáries, tratamento periodontal e de focos periapicais, orientação para higiene oral e dieta, e ainda laserterapia. É importante a inserção do dentista na equipe oncológica para o diagnóstico precoce das manifestações bucais e acompanhamento no período de tratamento.Several changes in the oral cavity due to chemotherapy can be observed and can lead to important systemic complications, increasing the time of the patient in hospital and the costs of the treatment as well as affect the quality of life of the patients. The aim of this study was to assess the oral manifestation in patients treated with chemoterapy according to sex, age and tumor type. Data was collected in an oncology hospital in Juiz de Fora, Minas Gerais State, from patients' records that were submitted to oncologic treatment. It was possible to verify that mucositis, associated or not to other type of lesions

  8. Delayed CTD and XBT data assembled and submitted by the Canada Department of Fisheries and Oceans (DFO) for the Global Temperature-Salinity Profile Program (GTSPP), dates range from 06/08/1979 - 05/25/2010 (NODC Accession 0065272)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Integrated Science Data Management (ISDM) office processes oceanographic profiles for the world oceans and submits these data to the Global Temperature and...

  9. XBT data collected by the Commonwealth Scientific Industrial Research Organization (CSIRO), and submitted to the Global Temperature-Salinity Profile Program (GTSPP), dates range from February 01, 2011 to December 31, 2011 (NODC Accession 0086084)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Physical data were collected using XBT profiles in the Indian Ocean from February 01, 2011 to December 31, 2011. Data were collected and submitted by the Australian...

  10. XBT data collected by the Australian Bureau of Meteorology (ABOM), and submitted to the Global Temperature-Salinity Profile Program (GTSPP), dates range from January 05, 2010 to January 04, 2011 (NODC Accession 0072587)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Physical data were collected using XBT profiles in the Indian Ocean from January 05, 2010 to January 04, 2011. Data were collected and submitted by the Australian...

  11. XBT data collected by the Australian Bureau of Meteorology (ABOM), and submitted to the Global Temperature-Salinity Profile Program (GTSPP), dates range from January 04, 2011 to December 29, 2011 (NODC Accession 0087991)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Physical data were collected using XBT profiles in the Indian Ocean from January 04, 2011 to December 29, 2011. Data were collected and submitted by the Australian...

  12. The Economics of Climate Change in Kenya: Final Report submitted in advance of COP15

    Energy Technology Data Exchange (ETDEWEB)

    Downing, Tom; Watkiss, Paul; Dyszynski, Jillian; Butterfield, Ruth; Devisscher, Tahia; Pye, Steve; Droogers, Peter; Ali, Basra; Harding, Brian; Tas, Adriaan; Blois, Mark de; Tadege, Abebe; Hunt, Alistair; Taylor, Tim; Bouma, Menno; Kovats, Sari; Maitima, Joseph; Mugatha, Simon; Kariuki, Patrick; Mariene, Lea; Worden, Jeff; Western, David; Waruingi, Lucy; Brown, Sally; Kebede, Abiy; Nicholls, Robert; Lager, Bo; Otiende, Brian; Chambwera, Muyeye; Birch, Tom; Mutimba, Stephen; Sang, Joan

    2009-12-15

    Existing climate variability has significant economic costs in Kenya. Periodic floods and droughts (extremes) cause major macro-economic costs and reductions in economic growth. Future climate change will lead to additional and potentially very large economic costs. These are uncertain. However, aggregate models indicate additional net economic costs (on top of existing climate variability) could be equivalent to a loss of almost 3% of GDP each year by 2030 in Kenya. Costs include potential threats to coastal zones (sea-level rise), health burdens, energy demand, infrastructure, water resources, agriculture and loss of ecosystem services. The study has addressed the potential impacts and economic costs in these sectors. These highlight the importance of preparing for future climate change. While it is difficult to predict effects with confidence, there is a need to plan robust strategies to prepare for the future, rather than using uncertainty as a reason for inaction. Adaptation can reduce the economic costs of climate change but it has a cost. The costs of adaptation are still emerging. A number of categories of adaptation have been identified that relate to the balance between development and climate change. An initial estimate of immediate needs for addressing current climate as well as preparing for future climate change for Kenya is USD 500 million/year (for 2012). The cost of adaptation by 2030 will increase: an upper estimate of the cost is likely to be in the range of USD 1 to 2 billion/year. The study has also prioritised early adaptation across the sectors. These studies demonstrate that adaptation has potentially very large benefits in reducing present and future damages. However, while adaptation reduces damages, it does not remove them entirely. Residual impacts in Kenya, particularly for some regions and groups are expected and need to be managed. The analysis has considered future emissions for Kenya, consistent with planned development. Emissions of greenhouse gases (GHG) could double between 2005 and 2030. Moreover, plans across the economy could 'lock-in' Kenya into a higher emission pathway. The study has investigated a low carbon alternative pathway. This finds that a large number of 'no regrets' options that would enhance economic growth, as well as allowing further access to international carbon credits. They also have economic benefits from greater energy security and diversity, reduced air pollution, reduced environmental impacts. The study estimates energy related emission savings of 22% could be achieved by 2020, relative to the baseline, even for a small selection of options. Over 80% of these options can be realized at net negative cost. When carbon credits are included, this amount is likely to be even higher. Overall, because of its location, availability of resources and socio-economic conditions, the study concludes that there are significant economic benefits for Kenya in following a low carbon development path, as well as large environmental and social benefits. The study has outlined a number of recommendations and future priorities

  13. Favorable Long-term Outcome in Patients Submitted to Liver Transplantation After Downstaging of Hepatocellular Carcinoma According to a Brazilian Selection Protocol.

    Science.gov (United States)

    Massarollo, P C B; Coppini, A Z; Salzedas-Netto, A A; Coelho, F F; Minami, T; Gonzalez, A M

    2016-09-01

    In October 2008, the Brazilian Ministry of Health authorized listing of downstaged hepatocellular carcinoma (HCC) for liver transplantation, according to a standardized protocol. The aim of this study was to compare the outcome of patients submitted to liver transplantation after downstaging of HCC with the results other standard indications in Brazil. We conducted a retrospective analysis of 2,667 adult 1st elective deceased-donor liver transplantations registered at the database of the Transplant Notification Center of the São Paulo State Health Secretariat. These cases are classified into 3 groups: "cirrhosis," including 1,709 patients transplanted because of end-stage liver disease; "Milan-HCC," including 873 HCC patients initially meeting the Milan criteria; and "downstaging" group, including 85 HCC patients submitted to tumor downstaging to the Milan criteria before liver transplantation. One-, 3-, 5-, and 6-year patients survivals were, respectively, 82.7%, 72.0%, 66.1%, and 66.1%, in the "downstaging" group and 76.7%, 68.4%, 63.9%, and 63.5% in the "Milan-HCC" group (P = .483). At the same time intervals, patient survivals were 67.8%, 62.9%, 60.9%, and 60.2% in the "cirrhosis" group. These probabilities were significantly lower than those of both "downstaging" (P = .047) and "Milan-HCC" (P = .001) groups. Patients submitted to liver transplantation after downstaging of HCC, according to a Brazilian selection protocol, present long-term outcomes similar to HCC patients initially within the Milan criteria and better survival than recipients with end-stage liver disease. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Association of oxidative stress and DNA damage with grafting time in patients with multiple myeloma and lymphoma submitted to autologous hematopoietic stem cell transplantation

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    Thayna Nogueira dos Santos

    Full Text Available ABSTRACT The aim of the study was to investigate the association between oxidative stress and DNA damage with grafting time in patients submitted to autologous hematopoietic stem-cell transplantation (HSCT. The study included 37 patients submitted to autologous HSCT diagnosed with Multiple Myeloma (MM and lymphoma (Hodgkin’s and non-Hodgkin’s. Biomarkers of oxidative stress and DNA damage index (DI were performed at baseline (pre-CR of the disease and during the conditioning regimen (CR, one day after the HSCT, ten days after HSCT and twenty days after HSCT, as well as in the control group consisting of 30 healthy individuals. The outcomes showed that both groups of patients had an hyperoxidative state with high DI when compared to baseline and to the control group and that the CR exacerbated this condition. However, after the follow-up period of the study, this picture was re-established to the baseline levels of each pathology. The study patients with MM showed a mean grafting time of 10.75 days (8 to 13 days, with 10.15 days (8 to 15 days for the lymphoma patients. In patients with MM, there was a negative correlation between the grafting time and the basal levels of GPx (r = -0.54; p = 0.034, indicating that lower levels of this important enzyme are associated with a longer grafting time. For the DI, the correlation was a positive one (r = 0.529; p = 0.030. In the group with lymphoma, it was observed that the basal levels of NOx were positively correlated with grafting time (r = 0.4664, p = 0.032. The data indicate the potential of these biomarkers as predictors of toxicity and grafting time in patients with MM and Lymphomas submitted to autologous HSCT.

  15. Study Design and Evaluation of Risk Minimization Measures: A Review of Studies Submitted to the European Medicines Agency for Cardiovascular, Endocrinology, and Metabolic Drugs.

    Science.gov (United States)

    Mazzaglia, Giampiero; Straus, Sabine M J; Arlett, Peter; da Silva, Daniela; Janssen, Heidi; Raine, June; Alteri, Enrica

    2017-11-09

    Studies measuring the effectiveness of risk minimization measures (RMMs) submitted by pharmaceutical companies to the European Medicines Agency are part of the post-authorization regulatory requirements and represent an important source of data covering a range of medicinal products and safety-related issues. Their objectives, design, and the associated regulatory outcomes were reviewed, and conclusions were drawn that may support future progress in risk minimization evaluation. Information was obtained from risk management plans, study protocols, clinical study reports, and assessment reports of 157 medicinal products authorized for cardiovascular, endocrinology, and metabolic indications. We selected observational studies measuring, as outcomes of interest, the relationship between the RMMs in place and (1) implementation measures, such as clinical knowledge or physicians` compliance to recommendations contained in the RMMs; and (2) occurrence or reduced severity of the adverse drug reactions for which the RMMs were required. Of 59 eligible studies (24 completed, 35 ongoing), 44 assessed implementation measures, whereas only 15 assessed safety outcomes (1 study as a single endpoint and 14 studies with other endpoints). Fifty-one studies used non-experimental designs and 25 studies employed electronic healthcare databases for analysis. Of the 24 completed studies, 17 were considered satisfactory and supported immediate regulatory decision making, 6 were considered inconclusive and required new evaluations, and 1 was terminated early because new safety restrictions were required, thereby necessitating a new evaluation. Compliance with agreed deadlines was considered acceptable in 21 of 24 completed studies; the average time for a submission was 37 months (standard deviation ± 17), with differences observed by type of data source employed. Three important gaps in the evaluation plans of RMMs were identified: lack of early feedback on implementation, limited

  16. PHYSICAL-CHEMICAL QUALITY OF MANGO ‘Ubá’ (Mangifera indica L. FRUITS SUBMITTED TO IMPACT MECHANICAL DAMAGE AT HARVEST

    Directory of Open Access Journals (Sweden)

    ANÁLIA LÚCIA VIEIRA PACHECO

    Full Text Available ABSTRACT The objective of this study was to evaluate the quality of ‘Ubá’ mango fruit submitted to mechanical damage. The fruits were harvested in the 2012/2013 harvest, and let to drop once on a flat, hard surface, simulating the harvesting process of ‘Ubá’ mango, which is to drop all the fruits of a plant when they are physiologically mature. Treatments consisted of different drop heights (zero, one, two, three, four and five meters, totaling six treatments. After the fall, the fruits were submitted to ripening, and then evaluated for fresh mass loss (FML, presence of external lesions (PEL, presence of internal lesions (PIL, soluble solids content (SS,titratable acidity (TA, pH, SS/TA ratio and vitamin C. There was no difference between fresh weight loss of the dropped fruits and control. Regarding the presence of external and internal lesions, damage in fruits due to drop height tends to increase. The fruits that were not dropped presented higher SS content than the others, while those that fell from a height of 5 m had the vitamin C content reduced by 27.78% compared to control. The decrease in SS content and vitamin C was influenced by damage caused by the impact. It is concluded that mechanical damage caused by the impact interferes in the main attributes of quality of fruits and pulp of “Ubá” mango.

  17. Quality of life of women submitted to myocardial revascularization surgery in a public hospital - doi:10.5020/18061230.2010.p237

    Directory of Open Access Journals (Sweden)

    Rafaela Melo de Oliveira

    2012-01-01

    Full Text Available Objective: To analyze the sociodemografic profile, risck factors and the quality of life of women submitted to myocardial revascularization surgery. Methods: We conducted a qualitative study by applying a questionnaire on lifestyle and risk factors and an interview with four guiding questions to 15 revascularized inpatients of cardiology units of a referral public hospital and who had no manifestations of depression prior to surgery. Results: The patients profile showed that 9 (60% were Caucasian, 8 (54% had incomplete primary education, 4(27% were housewives, 9 (60% lived in urban area, 10 (67% were married, all had a family income lower than three minimum wages and 4(27% had only two kids. From the content analysis of the interviews, the following categories aroused: religiosity, disruption with everyday life, family and quality of life. Conclusion: We found out that the knowledge about the psychosocial structure of each patient helps in the treatment of the individual submitted to myocardial revascularization. By identifying the lifestyle and risk factors, women promote self-knowledge, which can avoid habits that lead to cardiovascular diseases. We suggest the development of strategies for prevention and health promotion involving the patients and their families so that there is an extension of hospital care at home and a better adaptation to the new condition.

  18. Positive predictive values of Breast Imaging Reporting and Data System (BI-RADS® categories 3, 4 and 5 in breast lesions submitted to percutaneous biopsy

    Directory of Open Access Journals (Sweden)

    Gustavo Machado Badan

    2013-07-01

    Full Text Available Objective To evaluate the BI-RADS as a predictive factor of suspicion for malignancy in breast lesions by correlating radiological with histological results and calculating the positive predictive value for categories 3, 4 and 5 in a breast cancer reference center in the city of São Paulo. Materials and Methods Retrospective, analytical and cross-sectional study including 725 patients with mammographic and/or sonographic findings classified as BI-RADS categories 3, 4 and 5 who were referred to the authors' institution to undergo percutaneous biopsy. The tests results were reviewed and the positive predictive value was calculated by means of a specific mathematical equation. Results Positive predictive values found for categories 3, 4 and 5 were respectively the following: 0.74%, 33.08% and 92.95%, for cases submitted to ultrasound-guided biopsy, and 0.00%, 14.90% and 100% for cases submitted to stereotactic biopsy. Conclusion The present study demonstrated high suspicion for malignancy in lesions classified as category 5 and low risk for category 3. As regards category 4, the need for systematic biopsies was observed.

  19. A non-randomized comparative study using different doses of acyclovir to prevent herpes simplex reactivation in patients submitted to autologous stem cell transplantation

    Directory of Open Access Journals (Sweden)

    Angelo Atalla

    Full Text Available The reactivation of Herpes Simplex virus (HSV occurs in 70% to 80% of patients submitted to autologous stem cell transplantation (ASCT; it increases the severity of chemotherapy-induced mucositis. Therefore, the use of acyclovir in ASCT patients is considered standard practice. However, the minimum dose needed to prevent reactivation is a matter of debate. We compared two doses of acyclovir in a non-randomized fashion in 59 patients submitted to ASCT: 32 patients received a dose of 125 mg/m² IV every six hours and the subsequent 27 patients received a dose of 60 mg/m² IV every six hours. Viral excretion was evaluated through weekly viral culture of oral swabs. Grade 4 mucositis was more frequent in Group 1 (p= 0.03. The reactivation rates in Groups 1 and 2 were 9% and 4%, respectively (p= 0.62, 95% confidence interval -7 - 18. Prophylaxis with reduced doses of intravenous acyclovir seems to be as effective as a higher dose in inhibiting HSV reactivation, with a significant reduction in cost. Prospective randomized studies are needed to confirm our conclusions.

  20. Evaluation of opening pattern and bone neoformation at median palatal suture area in patients submitted to surgically assisted rapid maxillary expansion (SARME through cone beam computed tomography

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    Daniel Gomes SALGUEIRO

    2015-08-01

    Full Text Available AbstractSurgically assisted rapid maxillary expansion (SARME is the treatment of choice to adult patients even with severe transversal maxillary discrepancies. However, the adequate retention period to achieve the bone remodeling, thus assuring treatment stability, is controversial.Objective To evaluate the opening pattern and bone neoformation process at the midpalatal suture in patients submitted to surgically assisted (SARME through cone beam computed tomography (CBCT.Material and Methods Fourteen patients were submitted to SARME through subtotal Le Fort I osteotomy. Both the opening pattern and the mean bone density at midpalatal suture area to evaluate bone formation were assessed pre- and post-operatively (15, 60 and 180 days through CBCT.Results Type I opening pattern (from anterior to posterior nasal spine occurred in 12 subjects while type II opening pattern (from anterior nasal spine to transverse palatine suture occurred in 2 individuals. The 180-day postoperative mean (PO 180 of bone density value was 49.9% of the preoperative mean (Pre value.Conclusions The opening pattern of midpalatal suture is more related to patients’ age (23.9 years in type I and 33.5 years in type II and surgical technique. It was not possible to observe complete bone formation at midpalatal suture area at the ending of the retention period studied (180 days.

  1. Late follow-up of patients submitted to subtotal splenectomy: late clinical, laboratory, imaging and functional with preservation of the upper splenic pole

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    Andy Petroianu

    2008-09-01

    Full Text Available objective: To evaluate the follow-up of patients submitted to splenectomy with preservation of the upper splenic pole. Methods: All patients undergoing subtotal splenectomy were invited to be reviewed. A total of 86 patients submitted to this surgery were studied. The procedure was performed due to one of the following conditions: portal hypertension due to schistosomiasis (n = 43, trauma (n = 31, Gaucher’s disease (n = 4, myeloid hepatosplenomegaly due to myelofibrosis (n = 3, splenomegalic retarded growth and sexual development (n = 2, severe pain due to splenic ischemia (n = 2 and pancreatic cystadenoma (n = 1. All patients underwent hematologic tests, immunological assessment, abdominal ultrasonography, computed tomography (CT, scintigraphy and endoscopy. Rresults: Increased white blood cell and platelet counts were the only hematological abnormalities. No immune deficit was found. Esophageal varices were still present in patients who underwent surgery because of portal hypertension, but none had a re-bleeding event. The ultrasonography, tomography and scintigraphy confirmed the presence of functional splenic remnants without significant size alteration. Conclusions: Subtotal splenectomy seems to be a safe procedure that can be useful to treat conditions involving the spleen. The functions of the splenic remnants are preserved during long periods of time.

  2. Longitudinal study of the indirect immunofluorescence and complement fixation tests for diagnosis of chagas' disease in immunosuppressed patients submitted to renal transplantation

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    José Fernando de Castro Figueiredo

    1993-12-01

    Full Text Available Clinical and serological follow-up of 7 patients submitted to renal transplantation and presenting positive serological reactions to Chagas 'disease before immunossupression did not show significant changes in indirect immunofluorescence and complement fixation titres for Chagas ' disease, or signs and symptoms indicating exacerbation of the disease during follow- up. In addition, 18 of 66 recipients of renal transplants considered to be non-chagasic before immunosuppression showed at least one positive result to the indirect immunofluorescence test for Chagas ' disease during the study period. The results suggest that the immunosuppression State induced in chagasic patients submitted to renal transplant did notpromoted exacerbation of the chronic infection in these patients and not interfere with the serological response of chronic chagasics, thus permitting the use of these serologic reactions for diagnostic purposes in these cases. However, the positive results ofthe indirect immunofluorescence test in non- chagasic patients indicate the needforjudicious interpretation ofthe indirect immunofluorescence test for the diagnosis of Chagas' disease in renal transplanted patients.

  3. Trashepatic left gastric vein embolization in the treatment of recurrent hemorrhaging in patients with schistosomiasis previously submitted to non-derivative surgery

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    Paulo Fernandes Saad

    2012-12-01

    Full Text Available CONTEXT: Non-derivative surgical techniques are the treatment of choice for the control of upper digestive tract hemorrhages after schistosomotic portal hypertension. However, recurrent hemorrhaging due to gastroesophagic varices is frequent. OBJECTIVE: To evaluate the outcome of treatment based on embolization of the left gastric vein to control the reoccurrence of hemorrhages caused by gastroesophagic varices in patients with schistosomiasis previously submitted to non-derivative surgery. METHODS: Rates of reoccurrence of hemorrhages and the qualitative and quantitative reduction of gastroesophagic varices in patients undergoing transhepatic embolization of the left gastric vein between December 1999 and January 2009 were studied based on medical charts and follow-up reports. RESULTS: Seven patients with a mean age of 39.3 years underwent percutaneous transhepatic embolization of the left gastric vein. The mean time between azigoportal disconnections employed in combination with splenectomy and the percutaneous approach was 8.4 ± 7.3 years, and the number of episodes of digestive hemorrhaging ranged from 1 to 7 years. No episodes of reoccurrence of hemorrhaging were found during a follow-up period which ranged from 6 months to 7 years. Endoscopic postembolization studies revealed reductions in gastroesophagic varices in all patients compared to preembolization endoscopy. CONCLUSIONS: Percutaneous transhepatic embolization of the left gastric vein in patients with schistosomiasis previously submitted to surgery resulted in a decrease in gastroesophagic varices and was shown to be effective in controlling hemorrhage reoccurrence.

  4. In vitro evaluation of the effect of different polishing techniques on the surface roughness of composite resins submitted to at-home and in-office bleaching procedures.

    Science.gov (United States)

    de Oliveira Lima, Michele; Catelan, Anderson; Hernandes, Natália Maria Pinto; Giorgi, Maria Cecília Caldas; Ambrosano, Gláucia Maria Bovi; Lima, Débora Alves Nunes Leite

    2015-01-01

    Bleaching agents may affect the properties of dental materials. The aim of this study was to evaluate the effect of different polishing techniques on the surface roughness of composite resins submitted to the at-home and in-office bleaching treatment. Disc-shaped specimens were carried out of nanofilled and microhybrid composites (n = 10). Finishing step was performed after light curing (L1) and polishing after 24 h with two systems (L2). Then, specimens were submitted to the home or in-office bleaching procedures, and roughness was re-evaluated (L3). The surface roughness (Ra) readings were measured at L1, L2, and L3 times using a profilometer. Data were statistically analyzed by multiple-way analysis of variance and Tukey test (α = 0.05). The polishing procedures decreased Ra for both composites compared to baseline values (L1). The roughness of specimens polished with jiffy did not present significant difference after polishing step (L2) and bleaching treatment (L3). However, the groups polished with Sof-Lex discs had increase on the Ra values after bleaching. The polishing is an important procedure to reduce the roughness of dental restorations and composite surface polished with jiffy system improved the degradation resistance to the bleaching agents compared to Sof-Lex discs.

  5. Rhamdia quelen (Quoy & Gaimard, 1824, submitted to a stressful condition: effect of dietary addition of the essential oil of Lippia alba on metabolism, osmoregulation and endocrinology

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    Carine de Freitas Souza

    Full Text Available ABSTRACT The aim of this study was to evaluate the effect of the essential oil of Lippia alba (EOLA as a feed additive on ionoregulatory and metabolic parameters and pituitary hormones expression in silver catfish, Rhamdia quelen , submitted to a stressful condition (stocking density of 10.6 kg m-3 and limited space. Fish were fed with different concentrations of EOLA (0.0 - control, 0.25 and 0.50 mL kg food-1 for 20 days. Metabolic parameters were not affected by the diet, with the exception of alanine aminotransferase, which was higher in the liver of fish fed 0.50 mL EOLA kg food-1. Plasma ions and activity of H+-ATPase did not change, but fish fed 0.25 mL EOLA kg food-1 presented higher Na+/K+-ATPase activity. Somatolactin expression in the pituitary was higher in the fish fed 0.25 mL EOLA kg food -1, but the expression of growth hormone and prolactin did not change. Therefore, dietary EOLA does not exert a protective effect in R. quelen submitted to a stressful situation because it did not alter most measured parameters. The use of 0.25 mL EOLA kg food-1 seems to be more suitable than 0.50 mL EOLA kg food-1 since the latter may be related to liver damage.

  6. Peer review comments on drug trials submitted to medical journals differ depending on sponsorship, results and acceptance: a retrospective cohort study.

    Science.gov (United States)

    van Lent, Marlies; IntHout, Joanna; Out, Henk Jan

    2015-09-30

    During peer review, submitted manuscripts are scrutinised by independent experts to assist journal editors in their decision-making and to help improve the quality of articles. In this retrospective cohort study, peer review comments for drug trials submitted to medical journals were analysed to investigate whether there is a relation between the content of these comments and sponsorship, direction of results and decision about acceptance. Descriptive content analysis of reviewer comments made on manuscripts on drug trials submitted to eight medical journals (January 2010-April 2012). For each manuscript, the number of reviewers, decision about acceptance, sponsorship and direction of results were extracted. Reviewer comments were classified using a predefined checklist. Reviewer reports for 246 manuscripts were assessed. Industry-sponsored trials were more likely to receive comments about lack of novelty (8.9%) than industry-supported (2.5%) and non-industry trials (6.1%, overall p=0.038). Non-industry trials more often received comments about poor experimental design (69.7%) than industry-supported (58.8%) and industry-sponsored trials (52.9%, overall p=0.019). Non-industry trials were also more likely to receive comments regarding inappropriate statistical analyses (28.4%) than industry-supported (23.5%) and industry-sponsored trials (15.1%, overall p=0.006). Manuscripts with negative results were more likely to receive comments about inappropriate conclusions (29.3%) than those with positive results (18.9%, p=0.010). Rejected manuscripts had more often received comments on the research question not being clinically relevant (7.8%) than accepted manuscripts (1.6%, p=0.002), and also on lack of novelty (8.3% vs 2.6%, p=0.008) and poor experimental design (68.6% vs 50.5%, pinfluence the nature of comments other than appropriateness of the conclusion. Manuscript acceptance was primarily related to the research question and methodological robustness of studies

  7. Characteristics and fate of orthodontic articles submitted for publication: An exploratory study of the American Journal of Orthodontics and Dentofacial Orthopedics.

    Science.gov (United States)

    Farjo, Nadia; Turpin, David L; Coley, R Yates; Feng, Jianying

    2015-06-01

    In this study, we aimed to give insight into the article review process by investigating the characteristics and the fate of manuscripts submitted to the American Journal of Orthodontics and Dentofacial Orthopedics (AJO-DO). The following information was obtained for original articles submitted to the AJO-DO in 2008: (1) for rejected articles: the reasons for rejection and the journal of subsequent publication when applicable; (2) for accepted articles: the number of revisions and the time elapsed to publication; and (3) for all articles: study topic, study design, area of origin, and statistically significant findings. Findings were reported using descriptive statistics, the chi-square test for equality of proportions, and multiple regression where appropriate. Post-hoc pair-wise tests were checked against the Bonferroni correction to account for multiple testing. Of the 440 original articles submitted to AJO-DO in 2008, 116 (26%) were accepted and published an average of 21 months (SD, 5 months) after acceptance. Rejected articles totaled 324 (74%), with 137 (42%) finding subsequent publication an average of 22 months (SD, 11 months) after rejection by the AJO-DO. The top 3 reasons for rejection by the AJO-DO were (1) poor study design (59% of rejected articles), (2) outdated or unoriginal topic (42%), and (3) inappropriate for the AJO-DO's audience (27%). Manuscripts rejected for poor study design had the least success for subsequent publication, whereas those rejected as inappropriate for the AJO-DO had the highest rate of publication elsewhere. Area of origin was significantly associated with acceptance by the AJO-DO, with articles from United States and Canada most likely to be accepted (P Articles from countries with the lowest publication rate in the AJO-DO had the highest publication rate elsewhere. The presence of statistically significant findings was shown to be significantly associated with acceptance by the AJO-DO (P = 0.013) but not with

  8. Sensory evaluation of black beans submitted to gamma radiation from Cobalt-60; Avaliacao sensorial de feijao preto submetido a radiacao de Cobalto-60

    Energy Technology Data Exchange (ETDEWEB)

    Moura, Neila Camargo de; Canniatti-Brazaca, Solange Guidolin; Spoto, Marta Helena Fillet, E-mail: sgcbraza@esalq.usp.b [Escola Superior de Agricultura Luiz de Queiroz (ESALQ/USP), Piracicaba, SP (Brazil). Dept. de Agroindustria, Alimentos e Nutricao; Arthur, Valter [Centro de Energia Nuclear na Agricultura (CENA/USP), Piracicaba, SP (Brazil). Secao de Entomologia e Irradiacao de Alimentos

    2005-04-15

    The objective of this research was to evaluate the sensory aspects of black beans submitted to gamma radiation from {sup 60}Co. The study involved eight panelists, between 17 to 23 years old, who were selected and trained for the descriptive analysis of appearance, aroma, flavor and texture. The panelists analyzed alterations of appearance, aroma, flavor and texture of non-irradiated and irradiated black beans with doses 2, 4, 6, 8 and 10kGy. The results were analyzed by test F, ANOVA and the Tukey test (5%), with the use of computers and the sensory analysis software Compusense Five and SAS. The results showed that irradiated samples decreased the bitter flavor, accentuated color and brightness and samples non-irradiated dry texture. The radiation treatment is a good method for conservation of black beans in doses evaluated in this study.(author)

  9. The data submitted by the United Kingdom to the United Nations Scientific Committee on the Effects of Atomic Radiation for the 1977 report to the General Assembly

    CERN Document Server

    Taylor, F E; Webb, G A M

    1976-01-01

    The United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) was established by the General Assembly in 1955 to report on the exposure of man to ionising radiation. In the subsequent twenty years the Committee has covered most aspects of the subject with repeated reviews of the levels of exposure from fallout due to weapons testing. The Committee is currently preparing a further report on doses from all sources and an evaluation of their biological effects. This is expected to be published in 1977. To aid it in compiling this report the Committee requested Member States of the UN to submit national data on a wide range of sources of exposure. The Board was asked by the Foreign and Commonwealth Office to collate the information requested from the United Kingdom. Data were available in the scientific literature on some topics, such as medical irradiation and environmental radioactivity. On some other topics, particularly occupational exposure, data have been collected but seldom publishe...

  10. Desenvolvimento de tambaqui submetido a períodos de privação alimentar Growth of tambaqui submitted to different feed deprivation periods

    Directory of Open Access Journals (Sweden)

    Daniel Rabello Ituassú

    2004-12-01

    Full Text Available O objetivo deste trabalho foi avaliar o efeito da privação alimentar em parâmetros de crescimento e composição corporal de juvenis de tambaqui (Colossoma macropomum. Em um delineamento inteiramente casualizado, 180 juvenis pesando 75,68±8,62 g foram distribuídos em 12 tanques de 180 L e submetidos a quatro períodos de privação (0, 14, 21 e 28 dias. A massa média dos peixes ao final do período de privação alimentar foi menor à medida que o tempo de privação aumentou. Ao final do experimento, somente peixes submetidos a 14 dias de privação alcançaram a massa dos peixes alimentados sem restrição. O fator de condição não revelou diferenças significativas entre tratamentos ao final do período de privação ou ao final do experimento. As taxas de crescimento específico e o índice hepatossomático foram similares entre todos os tratamentos. Os peixes submetidos à privação exibiram os maiores valores de consumo diário de ração e os menores valores de eficiência alimentar. As porcentagens de umidade e proteína corporal foram maiores quanto maior o tempo de privação, mas não houve variações significativas dos níveis de extrato etéreo. Juvenis de tambaqui apresentam crescimento compensatório quando submetidos à privação alimentar.The objective of this study was to evaluate the effect of feed deprivation on juvenile tambaqui (Colossoma macropomum growth parameters and body composition. In a complete randomized design, one hundred and eighty fishes, weighting 75.68±8.62 g were maintained in twelve 180-L tanks and submitted to four feed deprivation periods (0, 14, 21 and 28 days. Average fish weight at the end of feed deprivation period tended to be lower as deprivation period increased. At the end of the experiment only the fishes submitted to 14 days of feed deprivation attained similar weight to fish fed without restriction. Condition factor did not show any differences among treatments at the final of the

  11. CO{sub 2} emission quotas submitted to public examination; Les quotas d'emissions de CO{sub 2} soumis a l'examen public

    Energy Technology Data Exchange (ETDEWEB)

    Lepetit, V

    2006-06-15

    Since June 26, 2006, the national plan of allocation of CO{sub 2} quotas for the 2008-2012 era (PNAQ 2) is submitted to the public examination. This text proposes to diminish by 2% the CO{sub 2} quotas allocated to the industry and to energy companies between 2008 and 2012. NGOs and companies strongly criticize this text but for opposite reasons: NGOs claim for more severity while industrialists consider that the efforts requested are too high. Among the critics, the optional measure of the PNAQ 2 plan of putting up 10% of the CO{sub 2} quotas to auction has received a mitigated acceptance. Short paper. (J.S.)

  12. Behavior in vitro of the dentin-enamel junction in human premolars submitted to high temperatures: prediction of the maximum temperature based on logistic regression analysis.

    Science.gov (United States)

    Mejía, C; Herrera, A; Sánchez, A I; Moreno, S; Moreno, F

    2016-07-01

    The aim of the study was to provide scientific evidence that would permit DEJ separation to be used as a parameter to estimate the temperature to which burnt, carbonized or incinerated cadavers or human remains had been subjected. A descriptive pseudo-experimental study was carried out in vitro using cone beam tomography to determine the physical behavior of the dentine-enamel junction in 60 human premolars submitted to high temperatures (200°C, 400°C, 600°C, 800°C and 1000°C). Spearman's concordance and correlation index was used to determine the relationship between longitudinal separation of the dentine-enamel junction (mm) and temperature (°C) and a simple linear regression model developed to show that once micro- and macrostructural changes are initiated in the enamel and dentine. The dentine-enamel junction begins to separate from the cervical towards the occlusal as temperature increases.

  13. A descriptive analysis of the antimicrobial susceptibility of mastitis-causing bacteria isolated from samples submitted to commercial diagnostic laboratories in New Zealand (2003-2006).

    Science.gov (United States)

    Petrovski, K R; Laven, R A; Lopez-Villalobos, N

    2011-03-01

    To describe the antimicrobial susceptibility of mastitis-causing bacteria isolated from milk samples submitted to commercial laboratories over a period of 40 months. The records of reported results of milk samples submitted by veterinary practitioners to five commercial veterinary laboratories in the North and South Islands of New Zealand, between August 2003 and December 2006 were reviewed. Logistic regression was used to analyse the effect of year, island, and the interaction of year and antimicrobial on the probability of antimicrobial susceptibility for each pathogen and antimicrobial combination, where the causative bacteria had >1,000 susceptibility tests in total and the antimicrobials was tested on >500 isolates. A total of 9,262 isolates were included in this study, with an average of nearly seven susceptibility tests per isolate, totalling 62,918 tests. Streptococcus uberis isolates demonstrated high overall susceptibility (>90.0%) to the majority of antimicrobial agents except ampicillin (81.7%), lincomycin (85.3%), trimethoprim/sulphonamide combination (88.6%), and, as expected, aminoglycosides (penicillin (73.1%), and streptomycin (71.7%). No antimicrobial was effective against all Staph. aureus isolates. Minor changes were found in the overall susceptibility of the main mastitis-causing bacteria between 2003 and 2006. The antimicrobial agents intended for treatment of bovine mastitis currently available in New Zealand generally demonstrated good in-vitro efficacy against streptococci and staphylococci, with the exception of aminoglycosides. Analysis of the results of antimicrobial susceptibility of bacterial isolates from milk samples from dairy cows in New Zealand provides useful data for surveillance purposes, and a baseline for identifying changes in antimicrobial sensitivity in this population. However, the variation in antimicrobial susceptibility between individual isolates means that these data are of limited value when determining treatment of

  14. The effects of a high dosage of creatine and caffeine supplementation on the lean body mass composition of rats submitted to vertical jumping training

    Directory of Open Access Journals (Sweden)

    Carneiro-Junior Miguel A

    2011-03-01

    Full Text Available Abstract Background The influences of creatine and caffeine supplementation associated with power exercise on lean body mass (LBM composition are not clear. The purpose of this research was to determine whether supplementation with high doses of creatine and caffeine, either solely or combined, affects the LBM composition of rats submitted to vertical jumping training. Methods Male Wistar rats were randomly divided into 8 groups: Sedentary (S or Exercised (E [placebo (Pl, creatine (Cr, caffeine (Caf or creatine plus caffeine (CrCaf]. The supplemented groups received creatine [load: 0.430 g/kg of body weight (BW for 7 days; and maintenance: 0.143 g/kg of BW for 35 days], caffeine (15 mg/kg of BW for 42 days or creatine plus caffeine. The exercised groups underwent a vertical jump training regime (load: 20 - 50% of BW, 4 sets of 10 jumps interspersed with 1 min resting intervals, 5 days/wk, for 6 weeks. LBM composition was evaluated by portions of water, protein and fat in the rat carcass. Data were submitted to ANOVA followed by the Tukey post hoc test and Student's t test. Results Exercised animals presented a lower carcass weight (10.9%; P = 0.01, as compared to sedentary animals. However, no effect of supplementation was observed on carcass weight (P > 0.05. There were no significant differences among the groups (P > 0.05 for percentage of water in the carcass. The percentage of fat in the group SCr was higher than in the groups SCaf and ECr (P Conclusions High combined doses of creatine and caffeine does not affect the LBM composition of either sedentary or exercised rats, however, caffeine supplementation alone reduces the percentage of fat. Vertical jumping training increases the percentages of water and protein and reduces the fat percentage in rats.

  15. Clinical impact of recovery room on post-operative walking performance in elderly patients submitted to hip surgery: a real-world analysis.

    Science.gov (United States)

    Conti, Duccio; Ballo, Piercarlo; Salucci, Laura; Benvenuti, Enrico; Metrangolo, Lorena; Barucci, Riccardo; Giulietti, Chiara; Giardini, Sante; Boccalini, Rossana; Santoro, Giovanni Maria; Sarti, Armando

    2017-12-02

    Strategies aimed at favouring functional recovery after surgery for hip fracture may be of clinical importance. To test the clinical utility of a recovery room (RR) in terms of postoperative walking performance in an elderly population submitted to hip fracture surgery. Postoperative walking performance at rollator was assessed in 242 consecutive orthogeriatric patients able to follow the institutional physiotherapy protocol starting on day 1 after hip surgery. Group 1 (n = 186, age 86.0 ± 9.3 years, 24.7% male) was admitted to the RR for postoperative monitoring, whereas Group 2 (n = 56, age 85.2 ± 5.7 years, 23.2% male) was directly admitted to the ward. The best performance observed during the first three postoperative days was considered. Group 1 showed a better walking performance than Group 2, with a 50% lower probability of walking  10 m (relative risk 2.10, p = 0.0005). Multivariable analysis confirmed a favourable independent effect of the RR stay on walking performance (β = 0.205, p = 0.005). Admission to the RR in elderly patients submitted to hip fracture surgery could have an independent beneficial effect on postoperative walking functional recovery. This beneficial effect could probably depend on the possibility of ensuring a more rapid management of postoperative issues CONCLUSIONS: These findings support the clinical utility of a RR implementation in facilities where hip surgery in elderly subjects is routinely performed.

  16. Lipid peroxidation and total radical-trapping potential of the lungs of rats submitted to chronic and sub-chronic stress

    Directory of Open Access Journals (Sweden)

    Torres R.L.

    2004-01-01

    Full Text Available Exposure to stress induces a cluster of physiological and behavioral changes in an effort to maintain the homeostasis of the organism. Long-term exposure to stress, however, has detrimental effects on several cell functions such as the impairment of antioxidant defenses leading to oxidative damage. Oxidative stress is a central feature of many diseases. The lungs are particularly susceptible to lesions by free radicals and pulmonary antioxidant defenses are extensively distributed and include both enzymatic and non-enzymatic systems. The aim of the present study was to determine lipid peroxidation and total radical-trapping potential (TRAP changes in lungs of rats submitted to different models of chronic stress. Adult male Wistar rats weighing 180-230 g were submitted to different stressors (variable stress, N = 7 or repeated restraint stress for 15 (N = 10 or 40 days (N = 6 and compared to control groups (N = 10 each. Lipid peroxidation levels were assessed by thiobarbituric acid reactive substances (TBARS, and TRAP was measured by the decrease in luminescence using the 2-2'-azo-bis(2-amidinopropane-luminol system. Chronic variable stress induced a 51% increase in oxidative stress in lungs (control group: 0.037 ± 0.002; variable stress: 0.056 ± 0.007, P < 0.01. No difference in TBARS was observed after chronic restraint stress, but a significant 57% increase in TRAP was presented by the group repeatedly restrained for 15 days (control group: 2.48 ± 0.42; stressed: 3.65 ± 0.16, P < 0.05. We conclude that different stressors induce different effects on the oxidative status of the organism.

  17. 78 FR 48152 - Notice Inviting Publishers To Submit Tests for a Determination of Suitability for Use in the...

    Science.gov (United States)

    2013-08-07

    ... published in the Federal Register, in text or Adobe Portable Document Format (PDF). To use PDF you must have... . Specifically, through the advanced search feature at this site, you can limit your search to documents... Secretary for Policy and Strategic Initiatives, Delegated Authority to Perform the Functions and Duties of...

  18. Synthesis of the investment program proposals submitted by RTE to CRE's approval; Synthese des propositions de programme d'investissement soumises par RTE a l'approbation de la CRE

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    Conformably to the French law from February 10, 2000, the French commission of electricity regulation (CRE) must proceed to the examination of the proposals submitted by the electricity transportation network (RTE) for the approval of its 2002 investments program devoted to the power grid. The main lines of the proposals submitted by RTE are described in this document: 1 - strategy of grid development (methodology, interconnections), 2 - methods of evaluation and selection of regional projects (replacement and development projects), 3 - main projects retained (main transportation network and interconnections, regional networks, remote control and safety systems), 4 - program financing plan. (J.S.)

  19. Disfagia orofaríngea em pacientes submetidos à entubação orotraqueal Oropharyngeal dysphagia in patients submitted to orotracheal intubation

    Directory of Open Access Journals (Sweden)

    Michele Ramos Grigio Kunigk

    2007-12-01

    Full Text Available OBJETIVO: Detectar e caracterizar as alterações da fase oral e faríngea da deglutição, bem como verificar a ocorrência de penetração e aspiração laríngeas em pacientes submetidos à entubação orotraqueal. MÉTODOS: O estudo incluiu 30 adultos internados na unidade de tratamento intensivo do Hospital Estadual Mário Covas, que receberam entubação orotraqueal no período de 40 horas a 15 dias. Todos foram submetidos, por duas vezes, à avaliação endoscópica da deglutição, na primeira e segunda semanas, após a extubação, sendo observadas as alterações da fase oral e faríngea da deglutição e a presença de penetração e aspiração laríngeas. RESULTADOS: Na primeira avaliação, as alterações da fase oral estiveram presentes em 19(63,3% pacientes e, na segunda, em 12(40%.As alterações da fase faríngea ocorreram na primeira avaliação em 27(90% pacientes e, na segunda, em 8(26,7%. A penetração e a aspiração laríngeas foram detectadas nas duas avaliações, sendo diferentes para cada consistência e volume testados. CONCLUSÃO: A população submetida à entubação orotraqueal após a extubação apresenta alterações das fases oral e faríngea da deglutição caracterizadas por uma variedade de comprometimentos e acompanhadas de penetração e aspiração laríngeas.PURPOSE: To detect and characterize alterations in the oropharyngeal phase of swallowing as well as to verify the occurrence of laryngeal penetration and aspiration in patients submitted to invasive mechanical ventilation. METHODS: The study consisted of 30 individuals hospitalized in the intensive care unit of the Mario Covas State Hospital, who received invasive mechanical ventilation. They were all submitted twice to endoscopic evaluation for swallowing disorders in the first and second week after extubation. Alterations were observed in the oro-pharyngeal phase of swallowing and also the presence of penetration and laryngeal aspiration

  20. Reproductive performance of sows submitted to intrauterine insemination Desempenho reprodutivo de matrizes suínas inseminadas pela técnica intrauterina

    Directory of Open Access Journals (Sweden)

    Éder Batalha Araújo

    2009-08-01

    Full Text Available The objective of this study was to evaluate the reproductive performance of sows artificially inseminated by the intrauterine (IAIU technique. The experiment was arranged in a randomized complete block design, with 300 sows being distributed in five insemination techniques: control, intra-cervical (IAIC with 3x10(9 spermatozoa/100 mL; intrauterine (IAIU with 1x10(9 spermatozoa/100 mL; intrauterine with com 1x10(9 spermatozoa/50 mL; intrauterine with 5x10(8 spermatozoa/100 mL; and intrauterine com 5x10(8 spermatozoa/50 mL. The sows submitted to intrauterine insemination presented a farrowing rate of 90.8% and return to estrus rate of 9.2%, which did not differ from the rates obtained by the intra-cervical technique (90.0% and 10.0%, respectively. Total litter size did not differ between the techniques, with the means being from 11.4 to 11.9 piglets at farrowing. Although 4.6% of the sows submitted to intrauterine artificial insemination had difficulty with pipette insertion into the cervix, 100% of them were inseminated. When evaluating semen backflow, no difference was found between the intra-cervical and intrauterine insemination techniques. However, total semen backflow was higher in sows submitted to inter-cervical insemination. No difference was found in the presence of blood between the two methods evaluated. Hence, any of the intrauterine insemination techniques can substitute inter-cervical artificial insemination without damaging the reproductive performance of the animals.Um experimento foi realizado com o objetivo de avaliar o desempenho reprodutivo de matrizes suínas inseminadas pela técnica intrauterina (IAIU. Em um delineamento inteiramente casualizado, 300 fêmeas foram distribuídas em cinco técnicas de inseminação: controle - intracervical (IAIC com 3x10(9 espermatozoides/100 mL; intrauterina (IAIU com 1x10(9 espermatozoides/100 mL; intrauterina com 1x10(9 espermatozoides/50 mL; intrauterina com 5x10(8 espermatozoides/100 m

  1. Ethical issues of informed consent in malaria research proposals submitted to a research ethics committee in Thailand: a retrospective document review.

    Science.gov (United States)

    Adams, Pornpimon; Prakobtham, Sukanya; Limpattaracharoen, Chanthima; Suebtrakul, Sumeth; Vutikes, Pitchapa; Khusmith, Srisin; Wilairatana, Polrat; Adams, Paul; Kaewkungwal, Jaranit

    2017-08-14

    The informed-consent process should be one of meaningful information exchange between researchers and study participants. One of the responsibilities of research ethics committees is to oversee appropriate informed consent. The committee must consider various matters before deciding whether the process is appropriate, including the adequacy and completeness of the written information provided to study participants, and the process of obtaining informed consent. This study aimed to identify, quantitatively and qualitatively, consent-related issues in different types of malaria proposals submitted to the Faculty of Tropical Medicine, Ethics Committee. This study reviewed proposal documentation submitted to two panels of the Ethics Committee of the Faculty of Tropical Medicine, Mahidol University, from 2011 to 2015. The documentation included proposals, notifications to researchers of review outcomes and ethical issues of concern to committee members. Each element of the informed-consent process was identified and analyzed by study classification, design, and specimen use, including whether the study involved a vulnerable population. Summative content analysis was used to analyze patterns of common issues raised in reviews. Of the 112 proposals reviewed, 63 required an informed consent process. All researchers proposed communicating with their study participants; however, about two-thirds needed to improve their explanations of study procedures (study activities and specimen/data-collection process) to participants. About 40% of the proposals attracted comments on informed-consent process elements--risk and discomfort, vulnerable status, and compensation. Studies that planned to collect or use new/linked specimens raised more issues around informed consent than studies using linked data/records. Studies that involved vulnerable populations raised more issues than those that did not. The committee usually asked researchers to clarify, elaborate, revise, or paraphrase

  2. CHANGES IN OSMOTIC AND IONIC INDICATORS IN Ananas comosus (L. cv. MD GOLD PRE-TREATED WITH PHYTOHORMONES AND SUBMITTED TO SALINE MEDIUM

    Directory of Open Access Journals (Sweden)

    YURI LIMA MELO

    Full Text Available ABSTRACT The aim of this study was to evaluate the effect of NaCl on the hydroponic culture of cv. MD Gold pineapple pretreated with the phytohormones naphthaleneacetic acid (NAA and 6-benzylaminopurine (BAP using indicators of water stress and osmotic adjustment. Pineapple seedlings from saline treatments in the absence (-NB and presence (+NB of the phytohormones during the in vitro culture were grown in Hoagland & Arnon (1950 nutrient solution in the absence and presence of different NaCl concentrations (50; 100 and 150 mM for 10 days in a greenhouse. Plants obtained from in vitro culture pretreated with phytoregulators (+NB showed distinct physiological responses compared to non-treated plants (-NB in relation to dry mass (DM in roots, electrolyte leakage (EL and Na+ and K+ concentrations in leaves and roots, and also regarding soluble sugars (TSS, free amino acids (TFAA and proline (PRO concentrations in leaves. Additionally, salt treatments induced similar responses in -NB and +NB plants, however differing in relation to intensity and the studied organs. The presence of NaCl in the solution reduced leaf DM in the -NB treatment, the leaf relative water content in -NB and +NB, and root RWC only in the -NB treatment. High levels of NaCl increased leaf EL in the +NB treatment. Potassium levels decreased with the increase of NaCl concentrations in nutrient solution for leaves and roots submitted to -NB treatment and for roots submitted to +NB treatment. Leaf potassium levels increased in +NB treatment regardless of salt treatment. No ionic toxic effects were identified except for roots subjected to 150 mM NaCl solution both for -NB and +NB conditions. TSS concentrations decreased with increasing NaCl concentration in leaves for both -NB and +NB treatments. Furthermore, TFAA and PRO showed increased levels in leaves subjected to saline stress, being more expressive in -NB treatment. In conclusion, pretreatment with growth regulators in pineapple

  3. Static balance and function in children with cerebral palsy submitted to neuromuscular block and neuromuscular electrical stimulation: study protocol for prospective, randomized, controlled trial.

    Science.gov (United States)

    Kazon, Soráia; Grecco, Luanda A C; Pasini, Hugo; Corrêa, João C F; Christovão, Thaluanna C L; de Carvalho, Paulo de Tarsocamillo; Giannasi, Lilian Chrystiane; Lucareli, Paulo R G; de Oliveira, Luis Vicente Franco; Salgado, Afonso Shiguemi Inoue; Sampaio, Luciana M M; Oliveira, Claudia S

    2012-05-16

    The use of botulinum toxin A (BT-A) for the treatment of lower limb spasticity is common in children with cerebral palsy (CP). Following the administration of BT-A, physical therapy plays a fundamental role in potentiating the functionality of the child. The balance deficit found in children with CP is mainly caused by muscle imbalance (spastic agonist and weak antagonist). Neuromuscular electrical stimulation (NMES) is a promising therapeutic modality for muscle strengthening in this population. The aim of the present study is to describe a protocol for a study aimed at analyzing the effects of NMES on dorsiflexors combined with physical therapy on static and functional balance in children with CP submitted to BT- A. Protocol for a prospective, randomized, controlled trial with a blinded evaluator. Eligible participants will be children with cerebral palsy (Levels I, II and III of the Gross Motor Function Classification System) between five and 12 years of age, with independent gait with or without a gait-assistance device. All participants will receive BT-A in the lower limbs (triceps surae). The children will then be randomly allocated for either treatment with motor physical therapy combined with NMES on the tibialis anterior or motor physical therapy alone. The participants will be evaluated on three occasions: 1) one week prior to the administration of BT-A; 2) one week after the administration of BT-A; and 3) four months after the administration of BT-A (end of intervention). Spasticity will be assessed by the Modified Ashworth Scale and Modified Tardieu Scale. Static balance will be assessed using the Medicapteurs Fusyo pressure platform and functional balance will be assessed using the Berg Balance Scale. The aim of this protocol study is to describe the methodology of a randomized, controlled, clinical trial comparing the effect of motor physical therapy combined with NMES on the tibialis anterior muscle or motor physical therapy alone on static and

  4. Static balance and function in children with cerebral palsy submitted to neuromuscular block and neuromuscular electrical stimulation: Study protocol for prospective, randomized, controlled trial

    Directory of Open Access Journals (Sweden)

    Kazon Soráia

    2012-05-01

    Full Text Available Abstract Background The use of botulinum toxin A (BT-A for the treatment of lower limb spasticity is common in children with cerebral palsy (CP. Following the administration of BT-A, physical therapy plays a fundamental role in potentiating the functionality of the child. The balance deficit found in children with CP is mainly caused by muscle imbalance (spastic agonist and weak antagonist. Neuromuscular electrical stimulation (NMES is a promising therapeutic modality for muscle strengthening in this population. The aim of the present study is to describe a protocol for a study aimed at analyzing the effects of NMES on dorsiflexors combined with physical therapy on static and functional balance in children with CP submitted to BT- A. Methods/Design Protocol for a prospective, randomized, controlled trial with a blinded evaluator. Eligible participants will be children with cerebral palsy (Levels I, II and III of the Gross Motor Function Classification System between five and 12 years of age, with independent gait with or without a gait-assistance device. All participants will receive BT-A in the lower limbs (triceps surae. The children will then be randomly allocated for either treatment with motor physical therapy combined with NMES on the tibialis anterior or motor physical therapy alone. The participants will be evaluated on three occasions: 1 one week prior to the administration of BT-A; 2 one week after the administration of BT-A; and 3 four months after the administration of BT-A (end of intervention. Spasticity will be assessed by the Modified Ashworth Scale and Modified Tardieu Scale. Static balance will be assessed using the Medicapteurs Fusyo pressure platform and functional balance will be assessed using the Berg Balance Scale. Discussion The aim of this protocol study is to describe the methodology of a randomized, controlled, clinical trial comparing the effect of motor physical therapy combined with NMES on the tibialis anterior

  5. Thermal conditioning during the first week on performance, heart morphology and carcass yield of broilers submitted to heat stress - doi: 10.4025/actascianimsci.v35i3.18707

    Directory of Open Access Journals (Sweden)

    Felipe Eduardo dos Santos Marques

    2013-07-01

    Full Text Available This study aimed to assess the influence of thermal conditioning during the first week, and to verify the effect of this, upon the heat challenge by the end of the productive period on performance, heart morphology and carcass yield. A total of 980 Ross male broiler chicks randomly assigned according to a completely randomized design with 4 treatment and 8 replications totaling 32 experimental units. The treatments consisted of different temperature ranges in the first week of life: thermal comfort temperature, temperature below the comfort zone, temperature above the comfort zone and thermal oscillation. At 35 days of age four replicates of each treatment were submitted or not to heat stress in last week's rearing (27 and 32°C. Animals submitted to thermal conditioning in the first week of life showed no adaptation to heat capable of increasing production and carcass characteristics when submitted to chronic heat stress during the final rearing period. Metabolic disorders such as ascites syndrome and sudden death syndrome can occur in both broilers reared above the temperature of thermal comfort in the first week, as those submitted to heat stress from 35 days of age, considering the heart morphometric analysis performed on these birds.  

  6. Preliminary study of radiographic technique x doses in patients submitted to standard radiographic exams; Observacoes preliminares da relacao entre tecnica radiografica e doses em pacientes submetidos a exames radiograficos convencionais

    Energy Technology Data Exchange (ETDEWEB)

    Tilly Junior, Joao G. [Secretaria de Estado da Saudedo Parana, Curitiba, PR (Brazil); Ghilardi Netto, Thomaz [Sao Paulo Univ., Ribeirao Preto, SP (Brazil). Centro de Instrumentacao e Dosimetria das Radiacoes

    1996-12-31

    An evaluation of entrance skin dose in patients submitted to actual examinations, arising from present radiographic procedure in 10 rooms in Curitiba, PR, Brazil between December/95 and April/96 is presented. The basis for extensive studies, on local or regional level, is outlined 3 refs., 2 figs.

  7. English Grammar Problems Seen in the Original Articles Submitted for Publication in Annals of Abbasi Shaheed Hospital and Karachi Medical and Dental College.

    Science.gov (United States)

    Aziz, Sina; Kashif, Mehwash; Aijaz, Maaziya

    2016-08-01

    To find out the frequency and type of English Grammar problems in original articles, submitted for publication in Annals of Abbasi Shaheed Hospital, Karachi. Across-sectional study. Department of Annals of Abbasi Shaheed Hospital and Karachi Medical and Dental College in January 2015. The study evaluated 28 original research articles, published in Annals of Abbasi Shaheed Hospital and Karachi Medical and Dental College during January 2013 to December 2014, for the English language mistakes in the manuscripts. The researchers evaluated English grammar problems in the manuscripts and recorded the details on a predesigned proforma. The data was analysed on SPSS version 19.0. The categorical variables were computed as percentage. It has been observed that all the manuscripts evaluated for English grammar mistakes, demonstrated language mistakes. The mean of mistakes in June 2014 was 14.6 ±2.26, while for December 2014 is 20.5 ±4.76. The mean for the year 2013 issues was 1 ±6.18 for June issue and 13.3 ±3.0 for December issue, respectively. The number of mistakes identified in the manuscripts in descending order included punctuation marks, use of inappropriate tense and voice, use of articles (a, an, the), use of prepositions, wordiness (excessive words), long sentences, spelling mistakes, flow of thought process, incomplete sentences, and frequent use of abbreviations. Alarge number of manuscripts revealed inappropriate use of punctuation marks followed by tenses, active and passive voices.

  8. A Proposal submitted to Biological Systems Science Division of DOE requesting Participant Support Costs for the Fifth International Conference on Polar and Alpine Microbiology

    Energy Technology Data Exchange (ETDEWEB)

    Priscu, John [Montana State Univ., Bozeman, MT (United States)

    2012-11-20

    The 5th International Conference on Polar and Alpine Microbiology (PAM5) was held in Big Sky, Montana (USA) from 8-12 September 2013. This meeting is a continuation of the highly successful meetings previously held in Rovaniemi, Finland (2004), Innsbruck, Austria (2006), Banff, Canada (2008) and Ljubljana, Slovenia (2011), which brought together leading international researchers and students in this field. The objectives of the Big Sky meeting were to bring together scientists, students and professionals to discuss all aspects of cold-adapted microorganisms and the roles they play in polar and alpine environments, to understand the role of these organisms in our search for life on other icy worlds, to address recent developments, and to exchange ideas and experiences on an international scale. The conference provided a multi-disciplinary forum to explore emerging areas in the field and as always, will have a wealth of opportunities for the exchange of ideas and building of collaborations. Funds were requested to help defray registration fees and travel costs of 13 early career scientists. Distribution of the funds were based on the quality of the abstracts submitted.

  9. Total training load may explain similar strength gains and muscle hypertrophy seen in aged rats submitted to resistance training and anabolic steroids.

    Science.gov (United States)

    Krause Neto, Walter; de Assis Silva, Wellington; Polican Ciena, Adriano; Bocalini, Danilo; Aparecido Baptista Nucci, Ricardo; Alberto Anaruma, Carlos; Florencio Gama, Eliane

    2017-08-17

    This study aimed to quantify training parameters and analyze the morphological response of aged muscles submitted to resistance training and anabolic steroids. Aged Wistar rats were divided into groups: C - initial control; CF - final control; CAS - control with anabolic steroid, RT - resistance training, and RTA - resistance training with anabolic steroid. Maximum carried load, absolute and relative loads increased significantly in RT and RTA. RTA demonstrated greater relative load than RT. Average total volume, total climbing volume, relative total volume, relative total climbing volume, and mean climbing volume were similar between groups RT and RTA. For soleus, CAS, RT, and RTA enlarged cross-sectional area of type I fibers and nuclear ratio. As for type II fibers, RTA was higher than C and CF. For plantaris, RT and RTA showed significant increases in myofibers type I compared to C and CF. For type II fibers, RTA showed a significant increase compared to C and CF. Regarding the nuclear ratio, RT and RTA showed a higher ratio than C, CF, and CAS. Our results demonstrated that both RT and RTA were not different among the analyzed morphological parameters. This fact can be explained by the absence of differences found in the training variables analyzed.

  10. A Study on the Directed Living Non-Related Donor Kidney Transplantation Submitted to the Hospital Transplant Ethics Committee at the National Kidney and Transplant Institute.

    Science.gov (United States)

    Suguitan, G; Arakama, M-H I; Danguilan, R

    2017-03-01

    In the latter part of 2009, the Department of Health of the Philippines prohibited kidney transplantation with non-related kidney donors. Hence, the National Kidney and Transplant Institute created a Hospital Transplant Ethics Committee. This study describes directed non-related kidney donation at the National Kidney and Transplant Institute. This retrospective study reviewed the profiles of recipients and directed living non-related kidney transplant donors submitted to the Hospital Transplant Ethics Committee. A total 74 recipients and donors were reviewed by the Hospital Transplant Ethics Committee in 2014. Donors initiated the talks about being a donor (75%) to repay the good deeds that were done by the recipient for them or their families; examples of which are: sometime in their lives they needed financial assistance for hospitalization for their relatives and it was the patient who paid the hospital bill; or because they pitied the recipient, whom they found to be a good person, thus they would want to give one of their kidneys. Seventy-four (100%) said that they were not expecting anything in return for this act but wanted to be of help to the recipient. Of these 74 cases, 70 cases (95%) were approved and the others were disapproved. With a Hospital Transplant Ethics Committee in place, directed kidney donation is a valuable tool as an additional source of kidney donor without violating any ethical issues. Copyright © 2016. Published by Elsevier Inc.

  11. A preliminary study of hardness and modulus of elasticity in sheep mandibles submitted to distraction osteogenesis and low-level laser therapy.

    Science.gov (United States)

    Freddo, Angelo-Luiz; Hübler, Roberto; de Castro-Beck, Carlos-Afonso; Heitz, Cláiton; de Oliveira, Marília-Gerhardt

    2012-01-01

    To investigate the quality of newly formed bone in sheep mandibles submitted to distraction osteogenesis and low-level laser therapy (LLLT), based on hardness and modulus of elasticity values. The ideal moment for laser application (during the latency/activation period vs. during the bone consolidation period) was also evaluated. Computed tomography imaging was used to assess relapse as a result of early device removal. Extraoral distraction devices were placed in five sheep so as to achieve 1.5 cm of lengthened bone in 60 days. Distraction devices were removed 50, 40, and 33 days after surgery. Four animals were treated with LLLT, at different times, and one was used as control (no LLLT). When applied during the bone consolidation period, LLLT caused an increase in hardness and modulus of elasticity values. On the other hand, animals irradiated with LLLT during the latency/activation period presented a delay in bone healing. A period of consolidation of 13 days (early device removal) was associated with relapse. Nanoindentation tests were able to detect slight abnormalities in bone metabolism and proved to be important tools for the assessment of bone quality following distraction osteogenesis. LLLT provided increased benefits when applied during the bone consolidation period, once it promoted an increase in hardness and modulus of elasticity values. According to our results, the bone consolidation period should be of at least 3 weeks, so as to prevent relapse.

  12. X-ray microtomography in the micromorphologic characterization of soil submitted to different management; Microtomografia de raios-X na caracterizacao micromorfologica de solo submetido a diferentes manejos

    Energy Technology Data Exchange (ETDEWEB)

    Passoni, Sabrina

    2013-07-01

    The X-ray computed microtomography (CT) represents a non-invasive technique that can be used with success to analyze physical properties by the soil scientists without destroying the structure of the soil. The technique has as advantage over conventional methods the characterization of the soil porous system in three dimensions, which allow morphological property analyses such as connectivity and tortuosity of the pores. However, as the soil is a non-homogeneous and complex system, the CT technique needs specific methodologies for digital image processing, mainly during the segmentation procedure. The objectives of this work were: 1) to develop a methodology for microtomographic digital image processing; 2) to characterize the soil structure by using micromorphology analysis of samples submitted to non-tillage and conventional systems collected in three distinct layers (0-10, 10-20 and 20-30 cm); and 3) to identify possible changes in the porous system of the soil analyzed due to the effect of different management systems. The use of the CT technique and the procedures adopted for microtomographic digital image processing show to be efficient for the micromorphologic characterization of soil porous system. Soil under non-tillage system presented the best results from the agricultural point of view regarding porosity, total number of pores, connectivity and tortuosity in comparison to the conventional tillage. (author)

  13. WEIGHT LOSS AND NUTRITIONAL ANEMIA IN PATIENTS SUBMITTED TO ROUX-EN-Y GASTRIC BYPASS ON USE OF VITAMIN AND MINERAL SUPPLEMENTATION

    Science.gov (United States)

    RAMOS, Natalia Maria Coutinho Pinheiro de Jesus; MAGNO, Fernanda Cristina Carvalho Mattos; COHEN, Larissa; ROSADO, Eliane Lopes; CARNEIRO, João Régis Ivar

    2015-01-01

    Background Obesity is a chronic disease with high growth in population and bariatric surgery is currently considered the most effective treatment for weight reduction; on the other hand, nutritional deficiencies are observed after this procedure. Aim To analyze weight loss progression and nutritional anemia in patients submitted to Roux-en-Y gastric bypass on use of vitamin and mineral supplementation. Methods Retrospective analysis of 137 patients of both sexes, aged between 18-60 years, using supplemental multivitamins and minerals, were included; personal information, anthropometric and laboratory data in the preoperative, 12, 24, 36 and 48 months postoperatively were collected. Results Postoperatively, in both sexes, occurred weight loss compared to the pre-operative weight gain at 48 months and maintenance of body mass index. There was a decrease in the percentage of excess weight loss at 48 months postoperatively compared to the time of 12, 24 and 36 months in men and decreased at 48 postoperative months compared to the time of 24 months in females. There was a decreased in serum ferritin in both sexes and increased serum iron at 48 months postoperatively in males. There was a decreased in vitamin B12 and folic acid increased serum at 48 postoperative months in females. Conclusions Surgical treatment was effective for reducing weight, body mass index reduction and achievement of success in the late postoperative period along with multivitamin and mineral supplementation on prevention of serious nutritional deficiencies and anemia. PMID:25861069

  14. Time-dependent analysis of nociception and anxiety-like behavior in rats submitted to persistent inflammation of the temporomandibular joint.

    Science.gov (United States)

    do Nascimento, Glauce Crivelaro; Leite-Panissi, Christie Ramos Andrade

    2014-02-10

    Temporomandibular disorder (TMD) is prevalent in dental clinics and can involve problems with the masticatory muscles or the temporomandibular joints (TMJ). The pain of TMD is frequently associated with inflammation in the TMJs, but it's etiology is considered to be multifactorial and includes biologic, behavioral, environmental, social, emotional and cognitive factors. The purpose of this investigation was to evaluate the anxiety-like behavior in rats exposed to temporomandibular inflammation via injection of Freund's Adjuvant (CFA) with the elevated plus maze (EPM) and light/dark box (LDB) tests and to evaluate nociceptive behavior with the von Frey test at different periods. Moreover, this study measured TMJ inflammation using plasma extravasation (Evans blue test) and the intraarticular infiltration of polymorphonuclear neutrophils (myeloperoxidase quantification). The results showed that rats that were submitted to TMJ inflammation exhibited a decreased number of entries into the open arms of the EPM and a decrease in the time spent in the light compartment and in the number of transitions in the LDB. Additionally, the number of entries in closed arms in the EPM, used as indicator of locomotor activity, did not alter between treatments. Furthermore, increases in mechanical sensitivity and increases in plasma extravasation in the joint tissue occurred throughout the inflammation process, along with an increase in myeloperoxidase in the synovial fluid of TMJ. Our results suggest that the temporomandibular inflammation induced by CFA produced anxiety-like behaviors in rats and induced nociceptive behavior across different periods of inflammation. Copyright © 2013 Elsevier Inc. All rights reserved.

  15. Espasmo hemifacial: resultados do tratamento cirúrgico em 14 casos Hemifacial spasm: report of 14 cases submitted to surgical treatment

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    Rui R. D. Carvalho

    1973-06-01

    Full Text Available Quatorze pacientes com espasmo hemifacial foram submetidos a exploração cirúrgica e neurolise do 7º par craniano no ângulo ponto-cerebelar. Em 7 pacientes havia indubitável compressão do nervo facial por alça anômala da artéria cerebelar anterior e inferior sendo que um paciente também apresentava malformação de Arnold-Chiari. Em um paciente havia aracnoidite envolvendo o nervo. Em 6 outros, o nervo achava-se aparentemente livre. Houve alívio imediato e duradouro do espasmo em 10 pacientes, 2 permaneceram inalterados e um apresentou recidiva após 10 meses. Houve um óbito no pós-operatório imediato, conseqüente a traumatismo craniano por queda do paciente.Fourteen patients with hemifacial spasm were submitted to surgical exposure and neurolysis of the seventh nerve at the cerebellopontine angle. Seven patients had an anomalous anterior inferior cerebellar artery pulsating on the nerve, being present in one patient also Arnold-Chiari malformation. Another patient had chronic arachnoiditis involving the facial nerve. In 6 patients no abnormalities were found in the posterior fossa. There was complete relief of the spasm in 10 patients, 2 were unchanged, 1 had recurrence 10 months later and 1 died in the post-operative period due to head injury sustained during a fall.

  16. Neuropsychological and quality of life assessment in patients with Parkinson's disease submitted to bilateral deep brain stimulation in the subthalamic nucleus

    Directory of Open Access Journals (Sweden)

    Alessandra Shenandoa Heluani

    Full Text Available ABSTRACT Deep brain stimulation (DBS has been widely used to control motor symptoms and improve quality of life in patients with Parkinsons disease (PD. Recently, DBS in the subthalamic nucleus (STN has become the preferred target for patients with mixed motor symptoms. Despite resultant motor and quality of life improvements, the procedure has been associated with cognitive decline, mainly in language skills, and also with psychiatric symptoms. Objective: To evaluate the influence of DBS in the STN on cognition, mood and quality of life. Methods: We studied 20 patients with PD submitted to DBS in the STN from May 2008 to June 2012 with an extensive battery of cognitive tests including memory, language, praxis, executive functions and attention assessments; the Parkinson's Disease Quality of Life Questionnaire (PDQ-39; and the Hospital Anxiety and Depression Scale (HAD, were applied both before and after the surgery. Data was analyzed using SPSS version 17.0 and results compared using the paired Student's t test. Results: A total of 20 patients with pre and post-operative assessments were included. A statistically significant improvement was found in total score and on subscales of mobility, activities of daily living and emotional well-being from the PDQ-39 (P=0.009, 0.025, 0.001 and 0.034, respectively. No significant difference was found on the cognitive battery or mood scale. Conclusion: DBS in the SNT improved quality of life in PD with no negative impact on cognitive skills and mood.

  17. Valeriana officinalis L. for conscious sedation of patients submitted to impacted lower third molar surgery: A randomized, double-blind, placebo-controlled split-mouth study

    Directory of Open Access Journals (Sweden)

    Marcos Luciano Pimenta Pinheiro

    2014-01-01

    Full Text Available Introduction: Anxiety is one of the components of patient stress in the dental office and is recognized as one of the main factors that negatively affect treatment. The control of anxiety can be performed through conscious sedation, for which benzodiazepine is the drug of choice in dental practice, however present side-effects. Objective: The objective of the following study is to evaluate the efficacy of Valeriana officinalis L. (Valerian for control of anxiety during the third molar surgery. Materials and Methods: A single oral dose of either Valerian (100 mg or placebo was randomly administered 1 h before each surgical procedure to 20 volunteers between 17 and 31 years of age. Anxiety level was assessed by physiological parameters (blood pressure and heart rate [HR] and the observation of signs. Descriptive analysis, Chi-square test, Friedman test, Wilcoxon test and effect size test were performed (P < 0.05. Results: According to the researcher′s (80% and surgeon′s (75% evaluations, the patients treated with Valerian were calmer and more relaxed during surgery. Valerian had a greater effect on the maintenance of systolic blood pressure and HR after surgery. Conclusion: Valerian was more effective at controlling anxiety than a placebo when used for the conscious sedation of adult patients submitted to impacted lower third molar surgery.

  18. Morphologic analysis, by means of scanning electron microscopy, of the effect of Er: YAG laser on root surfaces submitted to scaling and root planing

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    Theodoro Letícia Helena

    2002-01-01

    Full Text Available The purpose of this study was to morphologically evaluate, by means of scanning electron microscopy, the effects of Er:YAG laser on the treatment of root surfaces submitted to scaling and root planing with conventional periodontal instruments. Eighteen root surfaces (n = 18, which had been previously scaled and planed, were assigned to 3 groups (n = 6. The control Group (G1 received no further treatment; Group 2 (G2 was irradiated with Er:YAG laser (2.94 mum, with 47 mJ/10 Hz, in a focused mode with air/water spray during 15 s and with 0.57 J/cm² of fluency per pulse; Group 3 (G 3 was irradiated with Er:YAG laser (2.94 mum, with 83 mJ/10 Hz, in a focused mode with air/water spray during 15 s and with 1.03 J/cm² of fluency per pulse. We concluded that the parameters adopted for Group 3 removed the smear layer from the root surface, exposing the dentinal tubules. Although no fissures, cracks or carbonized areas were observed, an irregular surface was produced by Er:YAG laser irradiation. Thus, the biocompatibility of the irradiated root surface, within the periodontal healing process, must be assessed.

  19. Vertiginous Symptoms and Objective Measures of Postural Balance in Elderly People with Benign Paroxysmal Positional Vertigo Submitted to the Epley Maneuver.

    Science.gov (United States)

    Silva, Camila Nicácio da; Ribeiro, Karyna Myrelly O B de Figueiredo; Freitas, Raysa Vanessa de Medeiros; Ferreira, Lidiane Maria de Britho Macedo; Guerra, Ricardo Oliveira

    2016-01-01

    Introduction Benign Paroxysmal Positional Vertigo (BPPV) is one of the most common and treatable causes of peripheral vestibular vertigo in adults. Its incidence increases with age, eventually leading to disability and a decreased quality of life. Objective The research aims to assess short-term effects of Otolith Repositioning Maneuver (ORM) on dizziness symptoms, quality of life, and postural balance in elderly people with Benign Paroxysmal Positional Vertigo. Methods A quasi-experimental study, which evaluated 14 elderly people that underwent the Otolith Repositioning Maneuver and reevaluation after one week. The authors performed statistical analysis by descriptive analysis of central tendency and dispersion; for pre- and post-treatment conditions, the authors used the Wilcoxon test. Results All aspects of the Dizziness Handicap Inventory (physical, functional, emotional, and total scores) as well as the Visual Analogue Scale (VAS) decreased after therapy (p Benign Paroxysmal Positional Vertigo submitted to Otolith Repositioning Maneuver. However, most of the participants did not overcome Benign Paroxysmal Positional Vertigo and not all aspects of postural balance improved. Therefore, a longer follow-up period and a multidisciplinary team are required to establish comprehensive care for elderly patients with dizziness complaints.

  20. Decreased Bone Mineral Density in Patients Submitted to Kidney Transplantation Is Related to Age, Body Mass Index, Time on Dialysis, and Hyperparathyroidism

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    Miguel Madeira

    2014-01-01

    Full Text Available Background. Renal transplantation (Tx influences bone mineral density (BMD by several mechanisms. The main objective of this study was to correlate BMD and risk factors associated with bone loss in patients submitted to kidney Tx. Methods. We evaluated 88 individuals after renal Tx (median time = 31.5 months since Tx. All of them sustained glomerular filtration rate ≥60 mL/min/1.73 m2. BMD was measured by dual-energy X-ray absorptiometry (DXA, Prodigy-GE. Calcium, phosphate, albumin, creatinine, and intact parathormone (PTH were measured at the same time. All statistical tests were two-sided and P value less than 0.05 were accepted as significant for all analyses in this study. Results. Serum PTH was raised in 42% patients, but corrected calcium was normal in 83 patients. No fragility fracture was reported, but the overall prevalence of osteoporosis was 27.6% and lower than expected BMD (Z-score ≤ −2.0 SD was observed in 28.4%. Patients with lower than expected BMD had higher PTH levels. Conclusions. Older age, lower body mass index (BMI, longer time on dialysis, and elevated PTH levels were identified as the main factors associated with lower BMD.